Specific IgE against milk allergens in children with insulin dependent diabetes mellitus.
Cow's milk has been considered as a possible trigger of the autoimmune response that destroys pancreatic B-cells, thus causing insulin dependent diabetes mellitus. We investigated 46 children with IDDM. In this group we showed an increased total IgE in 58.6% of cases and the presence of specific IgE antibodies induced by milk allergens in 32.5% of cases. These results suggests that antibodies probably play an important role in IDDM pathogenesis.
Boznański
A
A
Department of Pediatrics and Allergology, Medical Academy of Wrocław.
Pirogowicz
I
I
Wasik
R
R
Barg
E
E
Hebrowska
A
A
D000293:Adolescent; D000485:Allergens; D000818:Animals; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D008297:Male; D008892:Milk / Q000276:immunology*
D000485:Allergens; D007073:Immunoglobulin E