title: The effect of exogenous somatotropin on lactation performance of first-litter sows.
abstract: To determine the effect of exogenous porcine somatotropin (ST) on lactation performance of sows, 24 first-litter sows were injected daily at 0800 with either 10 mg of recombinant ST or an equivalent volume of buffer between d 8 and 39 of lactation. Litter size was standardized to six (n = 2), seven (n = 8), eight (n = 6), or 10 (n = 8) pigs within each pair of sows by fostering pigs within a few days after parturition. Milk yield and composition of sows given ST was similar at all stages of lactation to that of control sows. Combining treatment data revealed that the milk yield of sows was related linearly (P < .01) to litter size and was described with the following equation: MY = 1.03 (+/- .71) + .899 (+/- .102) LS (n = 24, r2 = .78), where MY is average milk yield (kilograms/day) of sows over 4 to 7, 11 to 14, 18 to 21, 25 to 32, and 32 to 39 d of lactation and LS is number of pigs in the litter. The body temperature of sows increased (P < .05) in response to administration of ST. Plasma IGF-I and glucose were increased (P < .05) by ST, but plasma urea concentrations were lower (P < .05) in ST-treated sows. Sows treated with ST lost more backfat (P < .05) during lactation, but neither voluntary feed intake nor body weight loss was significantly (P > .05) affected by ST. These data indicate that a 10-mg daily injection of ST from d 8 to 39 of lactation alters metabolism but does not increase milk production in lactating first-litter sows.
authors.affiliation: Victorian Institute of Animal Science, Werribee, Australia.
authors.forename: M S
authors.initials: MS
authors.lastname: Toner
authors.forename: R H
authors.initials: RH
authors.lastname: King
authors.forename: F R
authors.initials: FR
authors.lastname: Dunshea
authors.forename: H
authors.initials: H
authors.lastname: Dove
authors.forename: C S
authors.initials: CS
authors.lastname: Atwood
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D001831:Body Temperature / Q000502:physiology; D001835:Body Weight / Q000502:physiology; D004305:Dose-Response Relationship, Drug; D005260:Female; D013006:Growth Hormone / Q000494:pharmacology*; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D007774:Lactation / Q000187:drug effects* / Q000502:physiology; D016014:Linear Models; D008098:Litter Size; D008892:Milk / Q000378:metabolism; D013552:Swine / Q000378:metabolism / Q000502:physiology*; D014508:Urea / Q000097:blood
chemical_list: D001786:Blood Glucose; D007334:Insulin-Like Growth Factor I; D014508:Urea; D013006:Growth Hormone