Topical fluconazole therapy of Candida keratitis.
A prospective clinical trial of topical fluconazole solution (2 mg/ml) was undertaken in six consecutive eyes of microbiologically proven Candida keratitis with abscess formation. All eyes responded well to the medical therapy. Average duration required for healing was 22.6 +/- 2.3 days. The findings of our study suggest that topical fluconazole is a safe and effective antifungal drug for the management of Candida keratitis with deep abscess.
Panda
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Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Sharma
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N
Angra
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SK
D000038:Abscess / Q000188:drug therapy; D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D002177:Candidiasis / Q000188:drug therapy*; D002648:Child; D003316:Corneal Diseases / Q000188:drug therapy; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D007634:Keratitis / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D016896:Treatment Outcome
D015725:Fluconazole