Ursodeoxycholic acid in the treatment of primary sclerosing cholangitis.
Ursodeoxycholic acid treatment used in the management of primary sclerosing cholangitis leads to a rapid improvement in liver enzymes and is well tolerated in most patients. Fatigue and pruritus also showed an improvement, even if not significant compared with placebo, in some 50% of cases. Results of the investigations also showed that liver transplantation may be postponed in primary sclerosing cholangitis treated with ursodeoxycholic acid.
Stiehl
A
A
Medizinische Universitätsklinik, Heidelberg, Germany.
D002756:Cholagogues and Choleretics / Q000627:therapeutic use*; D015209:Cholangitis, Sclerosing / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008099:Liver / Q000473:pathology; D014580:Ursodeoxycholic Acid / Q000627:therapeutic use*
D002756:Cholagogues and Choleretics; D014580:Ursodeoxycholic Acid