Genetic analysis of a common oligogenic trait with quantitative correlates: summary of GAW9 results.
The statistical genetic analyses of a simulated data set for Genetic Analysis Workshop 9 Problem 2 are summarized. A diverse set of methods are evaluated with regard to the success with which they were able to determine the mode of inheritance and locate the genes underlying an oligogenically determined disease and four related quantitative traits.
Blangero
J
J
Department of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78228-0147, USA.
D002874:Chromosome Mapping; D003198:Computer Simulation; D030342:Genetic Diseases, Inborn / Q000235:genetics*; D008040:Genetic Linkage; D005838:Genotype; D006801:Humans; D008957:Models, Genetic; D010641:Phenotype; D013223:Statistics as Topic