Invasive vulvar carcinoma in two women infected with human immunodeficiency virus.
This report presents two HIV-infected women who developed invasive squamous cell carcinoma of the vulva. One patient was diagnosed with Stage II vulvar cancer 4 years after surgical excision of VIN. This patient underwent a hemivulvectomy and external-beam radiation therapy, but has subsequently developed recurrent vulvar cancer. The other patient was diagnosed with stage IV invasive vulvar cancer 1 year after the diagnosis of VIN and died of invasive vulvar cancer 11 months later. VIN should be considered a serious condition in HIV-infected women and clinicians should be careful to examine the vulva and perianal region in all HIV-infected women.
Wright
T C
TC
Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.
Koulos
J P
JP
Liu
P
P
Sun
X W
XW
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D002278:Carcinoma in Situ / Q000150:complications / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000473:pathology* / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D012086:Reoperation; D014846:Vulvar Neoplasms / Q000150:complications* / Q000473:pathology* / Q000601:surgery