A novel fucosyltetrahexosylceramide in plerocercoids of the parasite Spirometra erinacei.
This glycosphingolipid was tentatively designated as GalSEGLx, in which the carbohydrate structure is characterized by an additional galactose molecule attached to the reducing-end galactose of SEGLx [Gal beta-4 (Fuc alpha-3) Glc beta-3 Gal beta Cer], which was previously determined by us [Kawakami, Y., Nakamura, K., Kojima, H., Suzuki, M., Inagaki, F., Suzuki, A., Sonoki, S., Uchida, A., Murata, Y. & Tamai, Y. (1993) J. Biochem. 114, 677-683], through a beta 1-6 linkage. The ceramide contained sphinganine and 4D-hydroxysphinganine in an about equimolar ratio, and a non-hydroxy fatty acid with carbon atoms ranging from 16 to 28, 26:0, 28:0 and 28:1 being major components. Based on the finding that a novel carbohydrate structure. Gal beta-4 Glc beta-3 Gal, was commonly found in glycosphingolipids from the parasite, S. erinacei, we here propose the terms, spirometo series, for this core structure series, and spirometosides, for glycosphingolipids having this carbohydrate structure.
Kawakami
Y
Y
Department of Environmental Biology, Azabu University, Kanagawa, Japan.
Nakamura
K
K
Kojima
H
H
Suzuki
M
M
Inagaki
F
F
Suzuki
A
A
Ikuta
J
J
Uchida
A
A
Murata
Y
Y
Tamai
Y
Y
D000818:Animals; D002240:Carbohydrate Sequence; D002849:Chromatography, Gas; D005227:Fatty Acids / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry; D006028:Glycosphingolipids / Q000737:chemistry*; D006601:Hexoses / Q000032:analysis; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D008969:Molecular Sequence Data; D017421:Sequence Analysis; D013146:Spirometra / Q000737:chemistry*
D005227:Fatty Acids; D006028:Glycosphingolipids; D006601:Hexoses; C101337:fucosyltetrahexosylceramide