title: Inflammatory involvement of the hypophysis in Tolosa-Hunt syndrome.
abstract: We report a case of painful ophthalmoplegia (Tolosa-Hunt syndrome), which was complicated with diabetes insipidus (DI) and pituitary-adrenal axis hypofunction. A 42-year-old man hospitalized for left orbital pain and impairment of left cranial nerves III, IV, V, VI, developed diabetes insipidus during the corticosteroid treatment. Neuroimaging studies disclosed a thickened, highly contrast-enhanced pituitary stalk, swollen pituitary gland and widened left cavernous sinus up to the superior orbital fissure, which were accompanied by diabetes insipidus and hypofunction of the pituitary-adrenal axis. These were indicative of an extension of granulomatous inflammation of the cavernous sinus to the pituitary portal system and the gland itself.
authors.affiliation: Department of Neurology, Fukushima Medical College.
authors.forename: C
authors.initials: C
authors.lastname: Hida
authors.forename: T
authors.initials: T
authors.lastname: Yamamoto
authors.forename: K
authors.initials: K
authors.lastname: Endo
authors.forename: Y
authors.initials: Y
authors.lastname: Tanno
authors.forename: T
authors.initials: T
authors.lastname: Saito
authors.forename: T
authors.initials: T
authors.lastname: Tsukamoto
mesh_terms: D000328:Adult; D006801:Humans; D007249:Inflammation / Q000175:diagnosis / Q000209:etiology / Q000378:metabolism; D008297:Male; D009886:Ophthalmoplegia / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism; D010900:Pituitary Diseases / Q000175:diagnosis / Q000209:etiology* / Q000378:metabolism