title: Propranolol 4- and 5-hydroxylation and N-desisopropylation by cloned human cytochrome P4501A1 and P4501A2.
authors.affiliation: Department of Medicine, University of Melbourne, Austin.
authors.forename: M S
authors.initials: MS
authors.lastname: Ching
authors.forename: N
authors.initials: N
authors.lastname: Bichara
authors.forename: C L
authors.initials: CL
authors.lastname: Blake
authors.forename: H
authors.initials: H
authors.lastname: Ghabrial
authors.forename: R H
authors.initials: RH
authors.lastname: Tukey
authors.forename: R A
authors.initials: RA
authors.lastname: Smallwood
mesh_terms: D019388:Cytochrome P-450 CYP1A2 / Q000737:chemistry / Q000378:metabolism*; D019389:Cytochrome P-450 CYP2D6 / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D006900:Hydroxylation; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism*; D008968:Molecular Conformation; D011433:Propranolol / Q000031:analogs & derivatives* / Q000378:metabolism*
chemical_list: C012878:N-desisopropylpropranolol; C001422:4-hydroxypropranolol; D011433:Propranolol; D019388:Cytochrome P-450 CYP1A2; D019389:Cytochrome P-450 CYP2D6