Case report: ranitidine-induced bradycardia in a patient with dextrocardia.
Although rare, bradycardia and other cardiac arrhythmias have been associated with the use of H2-receptor antagonists. Ranitidine is among the most frequently prescribed drugs. In this article, the authors observed a ranitidine-mediated sinus bradycardia in a man with dextrocardia (situs inversus) who had acute bleeding from a duodenal ulcer. The bradycardia was resolved after ranitidine was discontinued.
Yang
J
J
Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Russell
D A
DA
Bourdeau
J E
JE
D000005:Abdomen / Q000000981:diagnostic imaging; D000328:Adult; D000897:Anti-Ulcer Agents / Q000009:adverse effects*; D001774:Blood Chemical Analysis; D001919:Bradycardia / Q000139:chemically induced*; D003914:Dextrocardia / Q000150:complications*; D004381:Duodenal Ulcer / Q000150:complications* / Q000628:therapy; D004562:Electrocardiography; D016145:Endoscopy, Digestive System; D006403:Hematologic Tests; D006635:Histamine H2 Antagonists / Q000009:adverse effects*; D006801:Humans; D008297:Male; D013902:Radiography, Thoracic; D011899:Ranitidine / Q000009:adverse effects*; D014463:Ultrasonography
D000897:Anti-Ulcer Agents; D006635:Histamine H2 Antagonists; D011899:Ranitidine