[The molecular genetic and biological aspects of the ecology of pathogenic Leptospira (Leptospira interrogans)].
The results of recent investigations on the application of some genotyping methods (genomic fingerprinting, analysis of restriction length fragment polymorphism of DNA, etc.), made in order to study the population structure of pathogenic leptospires and to evaluate their intraspecies heterogeneity with regard to their main ecological features, are reviewed. New data on the use of PRC-based amplification test systems for the study of specific features of host persistence of leptospires are presented. The relative role of the parasitic and saprophytic phases of existence for populations of pathogenic leptospires belonging to different intraspecies taxa is discussed.
Anan'ina
Iu V
IuV
D000818:Animals; D004269:DNA, Bacterial / Q000235:genetics; D004463:Ecology; D016680:Genome, Bacterial; D007921:Leptospira interrogans / Q000145:classification / Q000235:genetics* / Q000472:pathogenicity*; D016133:Polymerase Chain Reaction; D012703:Serotyping
D004269:DNA, Bacterial
Molekuliarno-geneticheskie i biologicheskie aspekty ékologii patogennykh leptospir (Leptospira interrogans).