title: [Prevalence of viral hepatitis in candidates for orthopedic surgery].
abstract: OBJECTIVE
  To study the prevalence of positive serology results for hepatitis B and C viruses among patients scheduled for elective orthopedic surgery, to establish risk groups and to assess the economic cost involved in testing patients in such groups.
  
  
  METHODS
  We performed a retrospective study of 1090 preoperative charts for patients awaiting elective orthopedic surgery between November 1993 and January 1995. Variables recorded were age, sex, physical status, history of alcoholism or addiction to injected drugs, associated disease (liver disease, chronic kidney failure and hemodialysis, and coagulation disorders), history of blood products transfusion, preoperative liver enzymes and blood levels of AcVHC and AgVHB as determined by enzyme immunoassay.
  
  
  RESULTS
  Mean age was 51.8 (SD 17.5). Women predominated, accounting for 60.6% of the sample. ASA I and ASA II patients accounted for 84.9%, 72 (6.61%) had had previous transfusions, 51 (4.6%) suffered liver disease, 4 (0.36%) had coagulation disorder, 5 (0.45%) were receiving hemodialysis for chronic kidney failure, and 5 (0.45%) admitted having injected drugs. We discovered alterations in preoperative liver enzyme levels in 116 (10.6%) cases. Sixty-five (5.96%) were positive for AcVHC and 13 (1.19%) were positive for AgVHB. Factors that predicted positive results for hepatitis C and B were liver disease, previous administration of blood products, chronic kidney failure requiring hemodialysis, drug addiction and high preoperative liver enzyme levels. Serologic testing for viruses performed on patients in this risk group would have detected 76.6% of the positive cases, resulting in savings of 90% of the cost of indiscriminate testing.
  
  
  CONCLUSIONS
  We believe that patients with histories of liver disease, blood product transfusion, chronic kidney failure with hemodialysis or drug addiction, or with high liver enzyme levels should be tested for hepatitis B and C before surgery.
authors.affiliation: Servicio de Anestesiología y Reanimación, Hospital de la Esperanza, IMAS, Barcelona.
authors.forename: X
authors.initials: X
authors.lastname: Santiveri
authors.forename: E
authors.initials: E
authors.lastname: Matute
authors.forename: F
authors.initials: F
authors.lastname: Escolano
authors.forename: J
authors.initials: J
authors.lastname: Castillo
authors.forename: E
authors.initials: E
authors.lastname: Bisbe
authors.forename: J
authors.initials: J
authors.lastname: Castaño
mesh_terms: D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000453:epidemiology; D001778:Blood Coagulation Disorders / Q000453:epidemiology; D015897:Comorbidity; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology* / Q000635:transmission; D006510:Hepatitis B Antibodies / Q000097:blood; D006526:Hepatitis C / Q000453:epidemiology* / Q000635:transmission; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D008107:Liver Diseases / Q000453:epidemiology; D008111:Liver Function Tests / Q000191:economics; D008297:Male; D008875:Middle Aged; D009985:Orthopedics; D011300:Preoperative Care / Q000191:economics; D015995:Prevalence; D006435:Renal Dialysis / Q000009:adverse effects; D012189:Retrospective Studies; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D013030:Spain / Q000453:epidemiology; D015819:Substance Abuse, Intravenous / Q000453:epidemiology; D065227:Transfusion Reaction
chemical_list: D006510:Hepatitis B Antibodies; D018937:Hepatitis C Antibodies
vernacular_title: Prevalencia de hepatitis virales en pacientes propuestos para cirugía ortopédica.