Progress in the application of scanning probe microscopy to biology.
Several key developments have occurred recently in the application of scanning probe microscopy to biology. These include the use of 'tapping-mode' atomic force microscopy both for the high-resolution imaging of biomolecules in liquids and for monitoring in situ biocatalysis, the use of atomic force microscopy as a force transducer to measure individual biological interactions, and the development of hybrid techniques such as scanning tunnelling microscopy coupled to confocal scanning laser microscopy.
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Hong Xing You, Department of Medicine and Molecular Genetics, Indiana University School of Medicine, Medical Research and Library Building, 975 West Walnut Street, Indianapolis, Indiana 46202-525, USA. Christopher R Lowe, Institute of Biotechnology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QT, UK.
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