title: Mitochondrial DNA analysis of Sporothrix schenckii in Costa Rica.
abstract: Mitochondrial DNA (mtDNA) types using restriction patterns with HaeIII were investigated in 21 clinical isolates of Sporothrix schenckii in Costa Rica. Nineteen isolates were found to be a new mtDNA type (Type 14), while the remaining two were Type 3 and Type 6. Based on the phylogeny of 14 mtDNA types constructed by estimating sequence divergences of mtDNA, S. schenckii were clustered into two main groups: Group A and Group B, with Type 14 and Type 3 included in Group A, and Type 6 in Group B. The results suggest that isolates of Group A may exist mainly in Central America including Costa Rica.
authors.affiliation: Department of Dermatology, Kanazawa Medical University, Ishikawa, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Ishizaki
authors.forename: M
authors.initials: M
authors.lastname: Kawasaki
authors.forename: M
authors.initials: M
authors.lastname: Aoki
authors.forename: M
authors.initials: M
authors.lastname: Miyaji
authors.forename: K
authors.initials: K
authors.lastname: Nishimura
authors.forename: J A
authors.initials: JA
authors.lastname: Garcia Fernandez
mesh_terms: D003364:Costa Rica; D004271:DNA, Fungal / Q000235:genetics*; D004272:DNA, Mitochondrial / Q000235:genetics*; D014644:Genetic Variation; D007564:Japan; D010802:Phylogeny; D015183:Restriction Mapping; D013175:Sporothrix / Q000235:genetics*
chemical_list: D004271:DNA, Fungal; D004272:DNA, Mitochondrial