Effect of levofloxacin-albumin Dacron graft on graft infection.
The susceptibility of Dacron grafts to infection is compared with Dacron grafts applied with levofloxacin-bonded albumin (LVFX-ALB) following the inoculation of 10(7) cells Staphylococcus aureus in rats. Staphylococcus epidermidis was inoculated in the same manner. While the control grafts were infected at the time of removal, the LVFX-ALB Dacron grafts resisted infection, thus demonstrating their effectiveness.
Fujimoto
K
K
First Department of Surgery, Nagoya University School of Medicine, Nagoya, Japan.
Yamamura
K
K
Hayashi
T
T
Osada
T
T
Sakurai
T
T
D000818:Animals; D001424:Bacterial Infections / Q000188:drug therapy*; D064704:Levofloxacin; D008297:Male; D015242:Ofloxacin / Q000494:pharmacology*; D011093:Polyethylene Terephthalates; D051381:Rats; D017207:Rats, Sprague-Dawley; D016378:Tissue Transplantation
D011093:Polyethylene Terephthalates; D064704:Levofloxacin; D015242:Ofloxacin