Early occurrence of a thyroid carcinoma in a patient who developed Graves' disease after treatment for Hodgkin's disease.
We report the case of a patient who developed Graves' disease and a papillary thyroid cancer only 5 years after irradiation and adjuvant chemotherapy for Hodgkin's disease. This case is peculiar for the very short latency time between Hodgkin's disease treatment and thyroid cancer development, an event possibly related to Graves' disease with elevated serum levels of TSAb. We conclude that, in patients treated for Hodgkin's disease, continued follow-up by clinical examination and sonography of the thyroid is needed, especially if they develop Graves' disease.
Belfiore
A
A
Cattedra di Endocrinologia, Ospedale Garibaldi, Catania, Italy.
Pellegriti
G
G
Milone
G
G
Vigneri
G
G
Gangemi
P
P
Fiumara
A
A
Vigneri
R
R
D000328:Adult; D002291:Carcinoma, Papillary / Q000150:complications* / Q000473:pathology; D005260:Female; D006111:Graves Disease / Q000150:complications* / Q000209:etiology / Q000473:pathology; D006689:Hodgkin Disease / Q000150:complications* / Q000473:pathology / Q000628:therapy; D006801:Humans; D013954:Thyroglobulin / Q000378:metabolism; D013964:Thyroid Neoplasms / Q000150:complications* / Q000473:pathology; D013965:Thyroidectomy
D013954:Thyroglobulin