False positive pleural biopsy and high CA125 levels in serum and pleural effusion in systemic lupus erythematosus.
A 23-year-old female with systemic lupus erythematosus is reported. The clinical features included fever, shortness of breath, lymphadenopathies, hepatosplenomegaly, pleural and pericardial fluids, ANA and Anti-DNA positivity. Pleural biopsy was false positive for malignancy on two occasions. High CA125 levels were detected in both serum and pleural fluid. Following prednisolone treatment, clinical and laboratory findings returned to normal.
Yücel
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AE
Department of Rheumatology, Haccttepe University, Ankara, Turkey.
Calguneri
M
M
Ruacan
S
S
D000328:Adult; D001706:Biopsy; D018394:CA-125 Antigen / Q000097:blood* / Q000378:metabolism*; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology*; D010994:Pleura / Q000473:pathology*; D010996:Pleural Effusion / Q000000981:diagnostic imaging / Q000378:metabolism*; D010997:Pleural Neoplasms / Q000473:pathology; D014057:Tomography, X-Ray Computed
D018394:CA-125 Antigen