[Amino acid pattern variation in animals after the administration of hypocaloric peripheral parenteral nutrition].
The pattern of intracellular aminoacids may be reproduced individually and is different for each illness. This study seeks to measure alterations in this pattern in rats after the administration of hypocaloric peripheral parenteral nutrition (HPPN), group B, for five days, by comparing them with rats subjected to conventional fluidtherapy, group A, for the same period. HPPN tolerance was good in all cases. Our results show a higher tendency to glyconeogenesis in group A, measured by a reduction in the glycogenic aminoacids especially alanine. An increase in branched aminoacids was observed in group A due to an increase in proteolisis. The animals in group B showed a lesser reduction in the intracellular aminoacids necessary for glyconeogenesis, especially glycine. HPPN, was found, to alter the aminoacids pattern in fasting rats. The results might be corroborated in humans studies.
de la Hoz Riesco
M L
ML
Servicio de Cirugía, Universidad de León.
Prieto Prado
M
M
García Vielba
J
J
García Díez
F
F
García Arumi
E
E
Culebras Fernández
J M
JM
D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D002149:Energy Intake; D008297:Male; D010288:Parenteral Nutrition; D051381:Rats; D017208:Rats, Wistar
D000596:Amino Acids
Variación del patrón de aminoácidos en animales tras la administración de nutrición parenteral periférica hipocalórica.