title: Proximal oesophageal pH-metry in children with respiratory symptoms.
abstract: Twenty-six children (mean age: 16.3 months) with vomiting and/or respiratory symptoms and 28 children (mean age 10.5 months) with vomiting and/or regurgitation underwent dual-site 24-hour oesophageal pH recording. Thirty-nine children had gastro-oesophageal reflux and in all of them, irrespective of respiratory symptoms, distal oesophageal acid exposure was significantly (p < 0.01) longer than proximal exposure. Furthermore, data from the proximal pH electrode were not significantly different between children with and without respiratory symptoms for any of the variables studied. In conclusion, no single features of reflux pattern, as determined by 24-hours pH-metry, account for respiratory symptoms in children with documented gastro-oesophageal reflux.
authors.affiliation: Dipartimento di Pediatria, Università Federico II, Napoli, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Staiano
authors.forename: P
authors.initials: P
authors.lastname: Basile
authors.forename: D
authors.initials: D
authors.lastname: Simeone
authors.forename: A
authors.initials: A
authors.lastname: Stanco
authors.forename: A
authors.initials: A
authors.lastname: Tozzi
authors.forename: M C
authors.initials: MC
authors.lastname: Caria
mesh_terms: D016022:Case-Control Studies; D004945:Esophagoscopy; D004947:Esophagus / Q000737:chemistry*; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D008297:Male; D018670:Monitoring, Ambulatory; D012140:Respiratory Tract Diseases / Q000175:diagnosis* / Q000209:etiology