title: Effect of pulse Doppler ultrasound on placental hormone excretion in vitro.
abstract: There is no literature data on the effects of ultrasound on the metabolism of placental tissue. In the present study, the authors have investigated the possible influence of pulsed field Doppler ultrasound on hormonal excretion of human placental trophoblasts in vitro. For the detection of placental hormones, specific immunoassays for chorionic gonadotropin (hCG), human placental lactogen (hPL), estrogen and progesterone were used. Compared to control trophoblast hormone excretion, pulsed field ultrasound exposure induced no changes in the excretion of the hormones in vitro. The authors were unable to demonstrate any alterations caused by pulsed field Doppler ultrasound in this in vitro model. Additional studies are required to deepen our understanding of the effect of pulsed Doppler ultrasound on other biomolecules and their metabolism.
authors.affiliation: Laboratory for Mineralized Tissue, Drago Perović Institute of Anatomy, Zagreb, Croatia.
authors.forename: S
authors.initials: S
authors.lastname: Martinović
authors.forename: E
authors.initials: E
authors.lastname: Suchanek
authors.forename: N
authors.initials: N
authors.lastname: Ljubojević
authors.forename: S
authors.initials: S
authors.lastname: Vukicević
authors.forename: V
authors.initials: V
authors.lastname: Latin
mesh_terms: D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000378:metabolism; D004958:Estradiol / Q000378:metabolism; D005260:Female; D006801:Humans; D010926:Placental Hormones / Q000378:metabolism*; D010928:Placental Lactogen / Q000378:metabolism; D011247:Pregnancy; D011374:Progesterone / Q000378:metabolism; D014327:Trophoblasts / Q000378:metabolism*; D018617:Ultrasonography, Doppler, Pulsed; D016216:Ultrasonography, Prenatal
chemical_list: D018997:Chorionic Gonadotropin, beta Subunit, Human; D010926:Placental Hormones; D011374:Progesterone; D004958:Estradiol; D010928:Placental Lactogen