title: In vivo and in vitro measurement of CYP2C19 activity.
authors.affiliation: College of Pharmacy, University of Kentucky 40536, USA.
authors.forename: P J
authors.initials: PJ
authors.lastname: Wedlund
authors.forename: G R
authors.initials: GR
authors.lastname: Wilkinson
mesh_terms: D001189:Aryl Hydrocarbon Hydroxylases; D065731:Cytochrome P-450 CYP2C19; D003577:Cytochrome P-450 Enzyme System / Q000032:analysis* / Q000235:genetics / Q000378:metabolism; D006801:Humans; D066298:In Vitro Techniques; D008617:Mephenytoin / Q000031:analogs & derivatives / Q000737:chemistry / Q000378:metabolism / Q000652:urine; D006899:Mixed Function Oxygenases / Q000032:analysis* / Q000235:genetics / Q000378:metabolism; D009853:Omeprazole / Q000378:metabolism; D010641:Phenotype; D011110:Polymorphism, Genetic; D013237:Stereoisomerism; D013379:Substrate Specificity
chemical_list: C025687:4-hydroxymephenytoin; D003577:Cytochrome P-450 Enzyme System; D006899:Mixed Function Oxygenases; D001189:Aryl Hydrocarbon Hydroxylases; C045793:CYP2C19 protein, human; D065731:Cytochrome P-450 CYP2C19; D009853:Omeprazole; D008617:Mephenytoin