[Genetic control of the induction of a nonculturable state in pathogenic bacteria].
The laboratory model for the induction of nonculturable forms in Salmonella typhimurium has been developed. S. typhimurium mutants with disturbances at different stages of their transfer from vegetative to nonculturable state have been obtained by insertion mutagenesis with the use of TnPhoA transposon. To identify the functions of genes involved in the process of the appearance of nonculturable forms, their cloning in the sequencing vector has been carried out.
Romanova
Iu M
IuM
Gintsburg
A L
AL
D000818:Animals; D003001:Cloning, Molecular / Q000379:methods; D003433:Crosses, Genetic; D003470:Culture Media; D004251:DNA Transposable Elements / Q000235:genetics; D051379:Mice; D009154:Mutation / Q000235:genetics; D010641:Phenotype; D016133:Polymerase Chain Reaction; D012486:Salmonella typhimurium / Q000235:genetics* / Q000254:growth & development / Q000472:pathogenicity*
D003470:Culture Media; D004251:DNA Transposable Elements
Geneticheskiĭ kontrol' induktsii nekul'tiviruemogo sostoianiia u patogennykh bakteriĭ.