[Micronization of phenytoin by precipitation].
Phenytoin was micronized by precipitation from its ammonia, ethanol, propanol, isopropanol and glacial acetic acid solutions. The precipitation was accomplished by either solvent evaporation, cooling of the solution or water addition into organic solvent solutions. The smallest particle size was obtained by evaporation of 20% ammonia solution.
Dobrucki
R
R
Katedra Technologii Postaci Leku, Akademia Medyczna, Poznań.
Wojciechowska
A
A
D011232:Chemical Precipitation; D010316:Particle Size; D010672:Phenytoin / Q000737:chemistry*
D010672:Phenytoin
Mikronizacja fenytoiny przez wytracanie.