Identification of the first retinoid X, receptor homodimer antagonist.
Canan Koch
S S
SS
Department of Retinoid Chemistry Research, Ligand Pharmaceuticals, Inc., San Diego, California 92121, USA.
Dardashti
L J
LJ
Hebert
J J
JJ
White
S K
SK
Croston
G E
GE
Flatten
K S
KS
Heyman
R A
RA
Nadzan
A M
AM
D000818:Animals; D002460:Cell Line; D002522:Chlorocebus aethiops; D004268:DNA-Binding Proteins / Q000037:antagonists & inhibitors; D018922:HL-60 Cells; D006801:Humans; D007202:Indicators and Reagents; D007700:Kinetics; D015394:Molecular Structure; D018168:Receptors, Retinoic Acid / Q000037:antagonists & inhibitors* / Q000096:biosynthesis; D011994:Recombinant Proteins / Q000037:antagonists & inhibitors / Q000096:biosynthesis; D047488:Retinoid X Receptors; D012176:Retinoids / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D014157:Transcription Factors / Q000037:antagonists & inhibitors* / Q000096:biosynthesis; D015533:Transcriptional Activation; D014162:Transfection
D004268:DNA-Binding Proteins; D007202:Indicators and Reagents; D018168:Receptors, Retinoic Acid; D011994:Recombinant Proteins; D047488:Retinoid X Receptors; D012176:Retinoids; D014157:Transcription Factors