[Vimentin expression during the differentiation of smooth myocytes of the bronchial wall in developing lungs].
Dynamics of vimentine synthesis and intensity of DNA synthesis in cells of myoblastic differon and epitheliocytes were analysed in developing lungs by means of immunocytochemistry. Monoclonal antibodies (MCA) reaction to vimentine with different cell structures alters in the course of prenatal ontogenesis. Granular type of the reaction, turning into the diffuse one was described on the early stages of differentiation. Expression of vimentine grows smaller in the course of differentiation in all the cell groups. The reaction was not in fact observed in definitive smooth myocytes. The process of the reduction of the MCA reaction intensity goes along with the DNA synthesis decrease in the cells described.
Zashikhin
A L
AL
Mikhaĭlov
V M
VM
D000375:Aging / Q000378:metabolism; D000818:Animals; D000831:Animals, Newborn; D001345:Autoradiography; D001980:Bronchi / Q000166:cytology / Q000196:embryology / Q000254:growth & development / Q000378:metabolism; D002454:Cell Differentiation; D004247:DNA / Q000096:biosynthesis; D005865:Gestational Age; D007150:Immunohistochemistry; D008168:Lung / Q000196:embryology* / Q000254:growth & development*; D051379:Mice; D024510:Muscle Development; D009130:Muscle, Smooth / Q000166:cytology / Q000196:embryology / Q000254:growth & development / Q000378:metabolism*; D014746:Vimentin / Q000096:biosynthesis*
D014746:Vimentin; D004247:DNA
Ekspressiia vimentina pri differentsirovke gladkikh miotsitov stenki bronkhov razvivaiushchikhsia legkikh.