title: [POEMS syndrome: role and value of interleukin-6].
abstract: POEMS syndrome is a systemic disorder with peripheral neuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes. The association of POEMS syndrome with lympho-proliferative disorder is very commun. The pathogenesis remains poorly understood but implication of cytokines (interleukins 1 and 6) is suspected. We report a case of a classic POEMS syndrome (with polyneuropathy, hepatomegaly, diabetes melitus, hyperpigmentation, monoclonal IgG lambda, anasarca and solitary plasmocytoma), associated with high serum levels of interleukin 6.
authors.affiliation: Service de médecine interne, CHU de Strasbourg, hôpital de Hautepierre, France.
authors.forename: E
authors.initials: E
authors.lastname: Andrès
authors.forename: F
authors.initials: F
authors.lastname: Courouau
authors.forename: G
authors.initials: G
authors.lastname: Kaltenbach
authors.forename: F
authors.initials: F
authors.lastname: Maloisel
authors.forename: M
authors.initials: M
authors.lastname: Imler
mesh_terms: D006801:Humans; D015850:Interleukin-6 / Q000097:blood / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D016878:POEMS Syndrome / Q000097:blood / Q000175:diagnosis / Q000503:physiopathology*; D011379:Prognosis
chemical_list: D015850:Interleukin-6
vernacular_title: Syndrome POEMS: rôles et intérêts de l'interleukine 6.