title: Angiomyolipoma arising in the colon.
abstract: Extrarenal angiomyolipomas are very rare. Here we report the first case of surgically resected angiomyolipoma of the descending colon that developed in a 50-yr-old man. The patient had no signs of or family history of tuberous sclerosis. He underwent a partial colectomy because the tumor obstructed the colon. Histologically, the tumor consisted of three components: mature fat cells, blood vessels, and smooth muscle cells, and was thereby diagnosed as an angiomyolipoma. Immunohistochemically, the proliferating smooth muscle cells were positive for vimentin, alpha-smooth muscle actin, and desmin. The tumor cells were negative for HMB-45, which is consistently expressed in renal angiomyolipomas.
authors.affiliation: Department of Pathology, Iwate Medical University School of Medicine, Japan.
authors.forename: C
authors.initials: C
authors.lastname: Maesawa
authors.forename: G
authors.initials: G
authors.lastname: Tamura
authors.forename: H
authors.initials: H
authors.lastname: Sawada
authors.forename: S
authors.initials: S
authors.lastname: Kamioki
authors.forename: Y
authors.initials: Y
authors.lastname: Nakajima
authors.forename: R
authors.initials: R
authors.lastname: Satodate
mesh_terms: D018207:Angiomyolipoma / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D003082:Colectomy; D003106:Colon / Q000473:pathology; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged