title: [Current aspects of para-suicidal poisoning].
abstract: BACKGROUND
  The study was designed to evaluate critically the background, findings and outcome in patients who have carried out suicidal and parasuicidal acts.
  
  
  METHODS
  All parasuicidal patients who were admitted to the Department of Medicine of the University of Mainz over a period of 1 year were investigated. The basic data of all patients was documented (time of the parasuicidal act, stay in hospital, clinical parameters, psychiatric appraisals and therapy instituted). The semistructured interview "European Parasuicide Study Interview Schedule (EPSIS)" of the WHO/EURO was used to record the psychosocial background.
  
  
  RESULTS
  The 153 patients were mostly suffering from intoxications with sedatives and psychoactive agents: they comprised 53 male (35%) and 100 female (65%) patients. The average age was 36 years. Eighty-two suicide patients were treated in the emergency admission section and 65 in intensive-care units. The duration of treatment in the emergency admission section averaged 9 hours, as compared to about 6 days on the intensive-care unit. Extracentral effects were most prominent amongst the "sequelae" of intoxications. Discharged directly to their homes were 58%, 31% to psychiatric hospitals and 9% to general wards; 2% died. The primary elimination of poison was achieved by induced vomiting in 40% of the cases, and by pumping out the stomach in 23%. There were no serious clinical alterations of clinical test parameters. Artificial ventilation was required in 8%. 107 suicide cases (61%) investigated psychiatrically showed moderate (41%) and severe (20%) psychological abnormalities. Depressive syndrome (35%, of these 1 third with major depression), which frequently occurred in the context of an acute stress reaction, predominated amongst the diagnoses. Forty-two patients could be interviewed 6 days after suicide or parasuicide. Of those 90% interviewed had visited their family doctor in the course of the year before the current admission. Thirty-one patients had already received outpatient therapy and 15 had undergone an inpatient form of psychiatric therapy.
authors.affiliation: Klinische Toxikologie, Johannes-Gutenberg-Universität Mainz.
authors.forename: L S
authors.initials: LS
authors.lastname: Weilemann
authors.forename: H J
authors.initials: HJ
authors.lastname: Hilgers
authors.forename: A
authors.initials: A
authors.lastname: Reckmann
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003422:Critical Care / Q000706:statistics & numerical data; D003430:Cross-Sectional Studies; D062787:Drug Overdose / Q000401:mortality* / Q000628:therapy; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D006993:Hypnotics and Sedatives / Q000506:poisoning*; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010348:Patient Care Team; D011619:Psychotropic Drugs / Q000506:poisoning*; D013405:Suicide / Q000706:statistics & numerical data*; D013406:Suicide, Attempted / Q000706:statistics & numerical data*; D015996:Survival Rate; D016896:Treatment Outcome
chemical_list: D006993:Hypnotics and Sedatives; D011619:Psychotropic Drugs
vernacular_title: Aktuelle Aspekte parasuizidaler Intoxikationen.