title: Caveolae and caveolins.
abstract: In the past year, we have witnessed considerable progress towards an understanding of the workings of caveolae. Highlights include the identification of new caveolin family members, the characterization of VIP21-caveolin as a cholesterol-binding oligomeric protein, and evidence for functional interactions between caveolins and heterotrimeric G proteins. In addition, novel systems for caveolae purification and for studying caveolae biogenesis are starting to reveal insights into the molecular basis of caveolae formation and function.
authors.affiliation: Department of Physiology & Pharmacology, Centre for Molecular and Cellular Biology, University of Queensland, 4072Brisbane, Australia. R.Parton@mailbox.uq.oz.au
authors.forename: R G
authors.initials: RG
authors.lastname: Parton
mesh_terms: D001692:Biological Transport; D051242:Caveolin 1; D022461:Caveolins; D002462:Cell Membrane / Q000502:physiology* / Q000648:ultrastructure; D004705:Endocytosis; D008565:Membrane Proteins / Q000145:classification / Q000378:metabolism*; D008954:Models, Biological; D015398:Signal Transduction
chemical_list: D051242:Caveolin 1; D022461:Caveolins; D008565:Membrane Proteins