A simian varicella virus (SVV) homolog to varicella-zoster virus gene 21 is expressed in monkey ganglia latently infected with SVV.
We have sequenced a simian varicella virus (SVV) open reading frame (ORF), 3,123 bp in length, whose product has 51% amino acid homology with the sequence encoded by the ORF of varicella-zoster virus gene 21. Several regions are highly conserved between the two ORFs, with homologies of approximately 80%. The SVV gene is transcribed in tissue culture cells productively infected with SVV and in monkey ganglia latently infected with SVV.
Clarke
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P
Department of Neurology, University of Colorado Health Sciences Center, Denver 80262, USA.
Matlock
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WL
Beer
T
T
Gilden
D H
DH
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D005724:Ganglia / Q000821:virology*; D000882:Haplorhini; D006566:Herpesviridae Infections / Q000473:pathology / Q000821:virology*; D006568:Herpesvirus 1, Cercopithecine / Q000235:genetics / Q000302:isolation & purification*; D014645:Herpesvirus 3, Human; D006801:Humans; D008969:Molecular Sequence Data