title: Leishmaniasis eco-epidemiology in the Alpujarra region (Granada Province, southern Spain).
abstract: An eco-epidemiological study was carried out in the region of the Alpujarras (southern Spain, Granada province). Nine villages were chosen at random in 5 bioclimatic zones. A study of leishmaniasis in the canine and human populations, was carried out concentrating especially upon schoolchildren. A total of 615 dogs were screened, which represents almost 100% of the canine census. Of the screened dogs, 33 showed an antibody titer > or = 1/160 when tested by IFA (seroprevalence of 5.3%). Age, sex, activity, and clinical symptoms of each dog were taken into account. Among the human population, infection from Leishmania was studied using the Leishmanin skin test (LST). Of 1286 people who were tested, 568 (44.16%) were positive. Most of the subjects were schoolchildren (878; practically 100% of the pupils), of whom 288 (32.8%) tested positive. A close relation was seen to exist between the percentage of positive LST's and age. Finally, a close relationship was also observed between canine seroprevalence and percentage of schoolchildren who tested positive in the LST, in the 5 bioclimatic zones under consideration.
authors.affiliation: Departamento Parasitología, Fac. Farmacia, Campus Universitario de Cartuja, Granada, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Acedo Sánchez
authors.forename: J
authors.initials: J
authors.lastname: Martín Sánchez
authors.forename: I D
authors.initials: ID
authors.lastname: Vélez Bernal
authors.forename: M C
authors.initials: MC
authors.lastname: Sanchís Marín
authors.forename: M
authors.initials: M
authors.lastname: Louassini
authors.forename: J A
authors.initials: JA
authors.lastname: Maldonado
authors.forename: F
authors.initials: F
authors.lastname: Morillas Márquez
mesh_terms: D000367:Age Factors; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D000953:Antigens, Protozoan / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D004283:Dog Diseases / Q000453:epidemiology / Q000469:parasitology*; D004285:Dogs; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D018314:Leishmania infantum / Q000276:immunology / Q000302:isolation & purification; D007898:Leishmaniasis, Visceral / Q000453:epidemiology* / Q000662:veterinary; D008297:Male; D016036:Seroepidemiologic Studies; D012737:Sex Factors; D012882:Skin Tests; D013030:Spain / Q000453:epidemiology
chemical_list: D000913:Antibodies, Protozoan; D000953:Antigens, Protozoan; C032127:leishmanin