Overexpression of vsr in Escherichia coli is mutagenic.
Overexpression of vsr in Escherichia coli stimulates transition and frameshift mutations. The pattern of mutations suggests that mutagenesis is due to saturation or inactivation of dam-directed mismatch repair.
Doiron
K M
KM
Biology Department, Concordia University, Montréal, Québec, Canada.
Viau
S
S
Koutroumanis
M
M
Cupples
C G
CG
D004260:DNA Repair / Q000235:genetics*; D004706:Endodeoxyribonucleases / Q000096:biosynthesis*; D004926:Escherichia coli / Q000235:genetics*; D016368:Frameshift Mutation; D016296:Mutagenesis / Q000235:genetics*
D004706:Endodeoxyribonucleases; C071421:vsr endonuclease