title: [Pharmacodynamic changes in the elderly subject].
abstract: Age-related physiological changes alter drug responsiveness in the elderly. The changes of pharmacokinetics are widely known but they do not explain completely the altered drug action in the elderly. In this work the authors deal with the alterations of pharmacodynamics which could be responsible for the different pharmacological action and the high frequency of side effects which can be found in old age.
authors.affiliation: I Divisione Medica Geriatrica, Azienda Ospedaliera di Verona.
authors.forename: G
authors.initials: G
authors.lastname: Beltrami
authors.forename: G
authors.initials: G
authors.lastname: Menegolli
authors.forename: C
authors.initials: C
authors.lastname: Bellamoli
authors.forename: L
authors.initials: L
authors.lastname: Grezzana
authors.forename: G
authors.initials: G
authors.lastname: Zavateri
mesh_terms: D000368:Aged; D000375:Aging / Q000187:drug effects* / Q000378:metabolism; D006706:Homeostasis / Q000187:drug effects; D006801:Humans; D010599:Pharmacokinetics; D011955:Receptors, Drug / Q000187:drug effects / Q000378:metabolism
chemical_list: D011955:Receptors, Drug
vernacular_title: Modificazioni della farmacodinamica nel soggetto anziano.