title: The hairpin stack fold, a novel protein architecture for a new family of protein growth factors.
abstract: The granulin/epithelin protein motif has an unusual structure consisting of a parallel stack of beta-hairpins stapled together by six disulphide bonds. The new structure also contains a folding subdomain shared by small toxins, protease inhibitors as well as the EGF-like protein modules.
authors.forename: R
authors.initials: R
authors.lastname: Hrabal
authors.forename: Z
authors.initials: Z
authors.lastname: Chen
authors.forename: S
authors.initials: S
authors.lastname: James
authors.forename: H P
authors.initials: HP
authors.lastname: Bennett
authors.forename: F
authors.initials: F
authors.lastname: Ni
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002347:Carps; D000077155:Granulins; D036341:Intercellular Signaling Peptides and Proteins; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry*
chemical_list: D000077155:Granulins; D036341:Intercellular Signaling Peptides and Proteins; D011506:Proteins