title: [Personal experience with use of Claforan in the form of a "protected coagulum" in patients after kidney transplantation].
abstract: Prophylaxis by means of antibiotics in the form of a so-called "protected coagulum" is an important part of prevention of postoperative infections in renal transplantations. The antibiotic is selected with regard to its effectiveness against the most frequent pathogens, tissue penetration, undesirable effects (in particular nephrotoxicity). The authors investigated a group of 450 renal transplantations with cefotaxime prophylaxis. During the four-week follow-up period after operation infection of the surgical wound (abscess, purulent secretion) occurred in 15 patients (3.33%). The mentioned results indicate that cefotaxime is suitable for use as a protected coagulum also in patients with postoperative immunosuppression.
authors.affiliation: Klinika kardiovaskulární a transplantacní chirurgie, IKEM, Praha.
authors.forename: L
authors.initials: L
authors.lastname: Janousek
authors.forename: M
authors.initials: M
authors.lastname: Adamec
authors.forename: V
authors.initials: V
authors.lastname: Rohn
authors.forename: M
authors.initials: M
authors.lastname: Kucera
authors.forename: J
authors.initials: J
authors.lastname: Pirk
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019072:Antibiotic Prophylaxis; D002439:Cefotaxime / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D013530:Surgical Wound Infection / Q000517:prevention & control*
chemical_list: D002439:Cefotaxime
vernacular_title: Nase zkusenosti s pouzitím Claforanu ve formĕ "chránĕného koagula" u nemocných po transplantaci ledviny.