A role for density functional calculations in the rational design of bioreductive cobalt complexes?
Wu
J H
JH
Department of Chemistry and Biological Chemistry, University of Essex, Colchester, UK.
Reynolds
C A
CA
D000970:Antineoplastic Agents / Q000737:chemistry*; D015687:Cell Hypoxia; D003035:Cobalt / Q000737:chemistry; D015195:Drug Design; D005029:Ethylenediamines / Q000737:chemistry* / Q000627:therapeutic use / Q000633:toxicity; D006801:Humans; D008466:Mechlorethamine; D008958:Models, Molecular; D008968:Molecular Conformation; D009369:Neoplasms / Q000188:drug therapy; D010084:Oxidation-Reduction
D000970:Antineoplastic Agents; D005029:Ethylenediamines; C100961:N,N-bis-(2-chloroethyl)ethylenediamine; D003035:Cobalt; D008466:Mechlorethamine