title: Personality deviation and gastric motility in patients with functional dyspepsia.
abstract: We studied gastric motor functions by scintigraphic gastric emptying analysis and surface electrogastrography (EGG), and personality trait deviation in patients with functional dyspepsia. Delayed gastric emptying was observed in 17/35 patients and reduced normal EGG activity in 22/35 functional dyspepsia patients. There was a highly significant negative correlation between the gastric retention rate (at 150 min) and the duration of normal EGG waves. Abnormally high T scores on the Minnesota Multiphasic Personality Inventory (MMPI) test (70 or above) were found in 14/21 patients. Hypochondriasis (Hs) and conversion hysteria (Hy) were the most common abnormal findings. Ninety percent of functional dyspepsia patients (19/21) had either gastric dysmotility and/or psychological deviation. Although there was no significant correlation between gastric dysmotility and deviation in personality traits in functional dyspepsia patients, these data suggest that brain-gut interactions may play an important role in the symptoms of functional dyspepsia.
authors.affiliation: Department of Psychosomatic Medicine, Tohoku University School of Medicine, Sendai, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kawakami
authors.forename: M
authors.initials: M
authors.lastname: Hongo
authors.forename: Y
authors.initials: Y
authors.lastname: Okuno
authors.forename: M
authors.initials: M
authors.lastname: Yamada
authors.forename: N
authors.initials: N
authors.lastname: Nishimura
authors.forename: S
authors.initials: S
authors.lastname: Fukudo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004415:Dyspepsia / Q000503:physiopathology* / Q000523:psychology*; D005260:Female; D005746:Gastric Emptying / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010554:Personality Disorders / Q000209:etiology* / Q000523:psychology; D011795:Surveys and Questionnaires