Assessment of the hemodynamic result of PTA with a Doppler guide wire: initial experience.
OBJECTIVE
To determine the usefulness of a Doppler guide wire for assessing the hemodynamic results of balloon dilation of atherosclerotic arterial obstruction.


METHODS
A 0.018-inch 12-MHz Doppler guide wire was used to measure the maximum peak velocity and the time-averaged peak velocity (APV) proximal to, inside, and distal to lesions in 10 consecutively seen patients (six men, four women; mean age, 68 years +/- 11 [standard deviation]). Measurements were made before and after percutaneous transluminal angioplasty (PTA).


RESULTS
The proximal-to-intrastenotic APV ratio was the best predictor of the grade of residual stenosis and correlated well with angiographic measurements (r = .8). Balloon dilation resulted in a significant increase in mean APV distal to the obstruction (12.5 cm/sec before versus 27.6 cm/sec after PTA; P < .05). The mean proximal-to-distal APV ratio also decreased significantly (3.7 before versus 1.0 after PTA; P < .005).


CONCLUSIONS
The Doppler guide wire can be used for direct intravascular evaluation of the result of balloon dilation in atherosclerotic obstructions.
Hoppe
M
M
Department of Diagnostic Radiology, University Hospital, Marburg, Germany.
Wagner
H J
HJ
Klose
K J
KJ
D000368:Aged; D000800:Angioplasty, Balloon / Q000295:instrumentation / Q000379:methods; D001161:Arteriosclerosis / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy*; D001783:Blood Flow Velocity; D005260:Female; D005263:Femoral Artery; D006801:Humans; D008297:Male; D011150:Popliteal Artery; D018608:Ultrasonography, Doppler / Q000295:instrumentation / Q000379:methods; D018084:Ultrasonography, Interventional / Q000295:instrumentation* / Q000379:methods