title: Malignant müllerian mixed tumor of the uterus with a prominent alpha-fetoprotein-producing component of yolk sac tumor.
abstract: We describe a case of a 64-year-old woman with a malignant müllerian mixed tumor of the uterus containing a prominent component of yolk sac tumor, which was associated with high serum levels of alpha-fetoprotein. The neoplasm pursued an aggressive course and the patient died 2 months postoperatively. This is the first case of this type and only the ninth alpha-fetoprotein-secreting endometrial cancer in the literature.
authors.affiliation: Department of Pathology and Laboratory Medicine, Vancouver Hospital and Health Sciences Centre, British Columbia, Canada.
authors.forename: M O
authors.initials: MO
authors.lastname: Shokeir
authors.forename: S M
authors.initials: SM
authors.lastname: Noel
authors.forename: P B
authors.initials: PB
authors.lastname: Clement
mesh_terms: D000328:Adult; D001344:Autopsy; D018240:Endodermal Sinus Tumor / Q000378:metabolism* / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D018200:Mixed Tumor, Mullerian / Q000473:pathology*; D014594:Uterine Neoplasms / Q000473:pathology*; D000509:alpha-Fetoproteins / Q000032:analysis / Q000096:biosynthesis*
chemical_list: D000509:alpha-Fetoproteins