A retrograde double-labeling study of uni- and bilaterally projecting retinal ganglion cells that project to the superior colliculi after unilateral eye removal at birth in the albino rat.
By injecting Fluoro-Gold and Evans-Blue into the right and left superior colliculi of the normal adult albino rats, bilaterally projecting retinal ganglion cells were labeled in the ventrotemporal crescent accounting for 37.9% of all the labeled cells, whereas in 0- and 5-day unilaterally enucleated rats these were found in the lower half of the retina accounting for 64.8% and 80.6%, respectively. Furthermore, they tended to have larger somata (type I cells).
Farid Ahmed
A K
AK
First Department of Anatomy, Kobe University School of Medicine, Japan.
Dong
K
K
Yamadori
T
T
D000818:Animals; D004996:Ethidium; D015353:Eye Enucleation; D005260:Female; D005456:Fluorescent Dyes; D008297:Male; D008845:Microinjections; D051381:Rats; D017208:Rats, Wistar; D012160:Retina / Q000166:cytology; D012165:Retinal Ganglion Cells / Q000166:cytology*; D013266:Stilbamidines; D013477:Superior Colliculi / Q000166:cytology*; D013997:Time Factors; D014795:Visual Pathways
C049774:2-hydroxy-4,4'-diamidinostilbene, methanesulfonate salt; D005456:Fluorescent Dyes; D013266:Stilbamidines; D004996:Ethidium