Massive verapamil overdose complicated by noncardiogenic pulmonary edema.
We describe two cases of pulmonary edema, bradycardia, and hypotension associated with massive verapamil overdose. A noncardiogenic etiology of the pulmonary edema was indicated in one patient by normal thermodilution cardiac output and pulmonary artery occlusion pressure, and in the other patient by a normal echocardiogram. We hypothesize that calcium channel blocker overdose predisposes patients to develop pulmonary edema.
Brass
B J
BJ
Department of Medicine, New York University Medical Center, NY 10016, USA.
Winchester-Penny
S
S
Lipper
B L
BL
D000328:Adult; D001919:Bradycardia / Q000139:chemically induced; D002121:Calcium Channel Blockers / Q000506:poisoning*; D003131:Combined Modality Therapy; D003422:Critical Care; D062787:Drug Overdose; D005260:Female; D006801:Humans; D008297:Male; D012128:Respiratory Distress Syndrome / Q000139:chemically induced* / Q000628:therapy; D013406:Suicide, Attempted; D014700:Verapamil / Q000506:poisoning*
D002121:Calcium Channel Blockers; D014700:Verapamil