title: Prevalence, antimicrobial properties and beta-lactamase production of haemolytic enterobacteria in patients with diarrhoea and urinary tract infections in Legos, Nigeria.
abstract: OBJECTIVE
  To determine the prevalence, antimicrobial properties and beta-lactamase production of haemolytic enterobacteria in patients with diarrhoea and urinary tract infections in Lagos, Nigeria.
  
  
  METHODS
  Hospital based prospective study.
  
  
  METHODS
  Total of 324 patients comprising 194 diarrhoeal and 130 urinary tract infection (UTI) cases.
  
  
  METHODS
  Production of haemolysms. beta-lactamase and antibiograms of isolates.
  
  
  RESULTS
  186 (57.41 pc) of the 324 clinical specimens screened were positive for enterobacteria, out of which 29 (15.59 pc) were haemolytic. Proteus vulgaris (2.78 pc) Klebsiella spp. (1.85pc). Escherichia coli (1.23 pc). Pseudomonas spp. (0.93 pc). Yersinia enterocolitics and Morganella morganii (0.62 pc). Salmonella spp. Vibrio cholerae and Proteus mirabilis (0.31pc) were the haemolytic enterobacteria Isolated. The susceptibilities of haemolytic bacteria to eight antibotics determined by disc-agar diffusion technique revealed that all 29 (100 pc) haemolytic isolates were sensitive to gentamycin and streptomycin but showed varied susceptibilities to the other drugs. Eleven (37.9 pc) of the 29 isolates produced beta-lactamase.
  
  
  CONCLUSIONS
  We conclude that gentamycin and streptomycin are effective drugs against haemolytic isolates from diarrhoea and UTI cases.
authors.affiliation: Department of Medical Microbiology and Parasitology College of Medicine University of Lagos.
authors.forename: C N
authors.initials: CN
authors.lastname: Kesah
authors.forename: A O
authors.initials: AO
authors.lastname: Coker
authors.forename: S A
authors.initials: SA
authors.lastname: Alabi
authors.forename: D K
authors.initials: DK
authors.lastname: Olukoya
mesh_terms: D003967:Diarrhea / Q000382:microbiology*; D004755:Enterobacteriaceae / Q000378:metabolism*; D004756:Enterobacteriaceae Infections / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D009549:Nigeria; D015995:Prevalence; D011446:Prospective Studies; D014504:Urban Health; D014552:Urinary Tract Infections / Q000382:microbiology*; D018440:beta-Lactam Resistance; D001618:beta-Lactamases / Q000096:biosynthesis*
chemical_list: D001618:beta-Lactamases