title: Total hip replacement in patients with hemophilia. 13 hips in 11 patients followed for 1-16 years.
abstract: During 1973-88, we performed 13 total hip replacements in 11 hemophilia patients, mean age 46 (25-65) years. During the operation, blood loss averaged 920 mL, and a mean of 120,000 units of factor VIII/IX were used. The mean duration of follow-up was 7 (1-16) years. 5 hips became loose within 6 years, and a further one after 13 years. 4 hips were revised, 2 of them due to infection in patients who were also seropositive for HIV. At the latest follow-up, 10 patients were alive. 6 had no hip pain and 7 could walk at least 1,000 meters at a time. Although these results are inferior to those obtained in arthrosis, total hip replacement should be considered in hemophiliac patients.
authors.affiliation: Department of Orthopedics, University Hospital, Malmö, Sweden.
authors.forename: T
authors.initials: T
authors.lastname: Löfqvist
authors.forename: L
authors.initials: L
authors.lastname: Sanzén
authors.forename: C
authors.initials: C
authors.lastname: Petersson
authors.forename: I M
authors.initials: IM
authors.lastname: Nilsson
mesh_terms: D000328:Adult; D000368:Aged; D016063:Blood Loss, Surgical; D005164:Factor IX / Q000627:therapeutic use; D005169:Factor VIII / Q000627:therapeutic use; D005500:Follow-Up Studies; D006467:Hemophilia A / Q000601:surgery*; D002836:Hemophilia B / Q000601:surgery*; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000502:physiology; D006622:Hip Prosthesis; D006801:Humans; D008124:Locomotion; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology; D011859:Radiography; D016059:Range of Motion, Articular; D012086:Reoperation
chemical_list: D005169:Factor VIII; D005164:Factor IX