[Markers of connective tissue dysplasia in patients with idiopathic atrioventricular valve prolapse and anomalously sited chordae tendineae].
Phenotype was investigated in 86 patients with idiopathic prolapses of atrioventricular valves and in 21 patients with displaced chordae. 10 and 4 markers of connective tissue dysplasia were distinguished for patients with the prolapses and anomalous chordae, respectively. For patients with dysplasia of connective tissue of the heart a modified version of phenotypical length is proposed: norm-anomalous chordae--prolapse of the 1st degree--prolapse of the 2nd degree. For patients with 3 and more markers echo-CG registration is advisable to reject mitral and/or tricuspid valves.
Martynov
A I
AI
Stepura
O V
OV
Ostroumov
O D
OD
D000015:Abnormalities, Multiple / Q000175:diagnosis / Q000235:genetics; D000328:Adult; D000886:Anthropometry; D002815:Chordae Tendineae / Q000002:abnormalities*; D003240:Connective Tissue Diseases / Q000175:diagnosis* / Q000235:genetics; D005260:Female; D005819:Genetic Markers; D006801:Humans; D008297:Male; D008945:Mitral Valve Prolapse / Q000175:diagnosis* / Q000235:genetics; D010641:Phenotype; D014263:Tricuspid Valve Prolapse / Q000175:diagnosis* / Q000235:genetics
D005819:Genetic Markers
Markery displazii soedinitel'noĭ tkani u bol'nykh s idiopaticheskim prolabirovaniem atrioventrikuliarnykh klapanov i s anomal'no rasplozhennymi khordami.