title: [Pituitary adenoma secreting prolactin. Results of their surgical treatment].
abstract: A retrospective study of 75 patients operated for pituitary prolactin-secreting adenomas between 1972 and 1992 is presented. 57 were women, 18 males. The major symptom was amenorrhea for women and impotence for men. Prolactinemia is correlated to the size of adenoma and thus permits a prediction of surgical results. Most of the patients with a prolactinemia under 300 ng/ml were cured by surgery alone. Surgical treatment alone at the-term follow-up cure 87% of the micro-adenomas, 17% of the enclosed adenomas, and none of the invasive adenomas. In this study there is only 7% of true recurrence. According to the high cure rate and low frequency recurrence after transphenoidal surgery for micro-adenomas we suggest this approach as the first choice treatment. On the other hand the best treatment for macro-prolactinomas is medicamentous.
authors.affiliation: Clinique de Neurochirurgie, Hôpital Cantonal Universitaire de Genève, Suisse.
authors.forename: P
authors.initials: P
authors.lastname: Otten
authors.forename: B
authors.initials: B
authors.lastname: Rilliet
authors.forename: A
authors.initials: A
authors.lastname: Reverdin
authors.forename: B
authors.initials: B
authors.lastname: Demierre
authors.forename: J
authors.initials: J
authors.lastname: Berney
mesh_terms: D000328:Adult; D003663:Decision Trees; D005260:Female; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local; D010911:Pituitary Neoplasms / Q000378:metabolism / Q000532:radiotherapy / Q000601:surgery*; D011388:Prolactin / Q000097:blood / Q000378:metabolism*; D015175:Prolactinoma / Q000532:radiotherapy / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D011388:Prolactin
vernacular_title: Les adénomes hypophysaires sécrétant de la prolactine. Les résultats de leur traitement chirurgical.