title: Long-term effects of consumption of full-fat or reduced-fat products in healthy non-obese volunteers: assessment of energy expenditure and substrate oxidation.
abstract: A study was performed to evaluate long-term (6-month) effects of consumption of full-fat products or reduced-fat products on energy and substrate metabolism. Subjects (age, 19 to 35 years; body mass index [BMI], 21 to 28 kg. m-2) were studied during a 36-hour stay in a respiration chamber, before (16 men) and in the third month (16 men) and sixth month (19 men and 17 women) of the study. The diet intervention caused, on average, a change in fat intake of (mean +/- SE) +23 +/- 31 g/d (P < .001) in the full-fat group and of -5 +/- 29 g/d (P .05) in the reduced-fat group. Twenty-four-hour energy expenditure (EE), sleeping metabolic rate (SMR), diet-induced thermogenesis (DIT), and EE for physical activity (ACT) were not different between the groups. Fat oxidation was significantly (P < .05) increased in the full-fat group and was not different from fat intake. During the 6 months of the study, body mass and fat mass were significantly increased in subjects of the full-fat group, whereas there were no changes in body mass or body composition in subjects of the reduced-fat group. It is concluded that in the long run, avoidance of a diet with full-fat products will promote body weight and fast stability.
authors.affiliation: Department of Human Biology, University of Limburg, Maastricht, The Netherlands.
authors.forename: W P
authors.initials: WP
authors.lastname: Verboeket-van de Venne
authors.forename: K R
authors.initials: KR
authors.lastname: Westerterp
authors.forename: T J
authors.initials: TJ
authors.lastname: Hermans-Limpens
authors.forename: C
authors.initials: C
authors.lastname: de Graaf
authors.forename: K H
authors.initials: KH
authors.lastname: van het Hof
authors.forename: J A
authors.initials: JA
authors.lastname: Weststrate
mesh_terms: D000328:Adult; D001823:Body Composition; D001835:Body Weight; D018752:Diet, Fat-Restricted; D004040:Dietary Carbohydrates / Q000008:administration & dosage; D004044:Dietary Proteins / Q000008:administration & dosage; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D008297:Male; D010084:Oxidation-Reduction; D012016:Reference Values; D013997:Time Factors
chemical_list: D004040:Dietary Carbohydrates; D004044:Dietary Proteins