Regional localization of human M-BCR gene to chromosome 23 band q11 in the great apes.
We hybridized a human M-BCR DNA probe to the chromosomes of chimpanzee (Pan troglodytes), gorilla (Gorilla gorilla) and orangutan (Pongo pygmaeus) by FISH-technique. The human M-BCR gene was localized to chromosome 23 band q11 (23q11), which is equivalent to the human chromosome 22 band q11 in all three species. The conservation of M-BCR gene in higher primates at the corresponding human chromosome locus provides phylogenetic clues concerning the evolution of genes.
Samonte
R V
RV
Division of Genetics, Long Island College Hospital, SUNY Health Science Center at Brooklyn, NY 11201, USA.
Ramesh
K H
KH
Verma
R S
RS
D000818:Animals; D002874:Chromosome Mapping; D002892:Chromosomes, Human, Pair 22; D015342:DNA Probes; D019143:Evolution, Molecular; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D015513:Oncogene Proteins / Q000235:genetics*; D011505:Protein-Tyrosine Kinases; D011518:Proto-Oncogene Proteins; D051562:Proto-Oncogene Proteins c-bcr
D015342:DNA Probes; D015513:Oncogene Proteins; D011518:Proto-Oncogene Proteins; D011505:Protein-Tyrosine Kinases; C496613:BCR protein, human; D051562:Proto-Oncogene Proteins c-bcr