Bioactive polyacetylenes from Bidens pilosa.
From the methanolic extract of the whole plants of Bidens pilosa the new beta-D-glucopyranosyloxy-3-hydroxy-6(E)-tetradecen-8, 10,12-triyne besides a known polyine has been isolated and identified mainly by IR and NMR methods. The new compound showed overgrowing action against normal and transformed human cell lines in culture.
Alvarez
L
L
Marquina
S
S
Villarreal
M L
ML
Alonso
D
D
Aranda
E
E
Delgado
G
G
D000480:Alkynes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D001419:Bacteria / Q000187:drug effects; D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D005960:Glucosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D006801:Humans; D007306:Insecticides / Q000737:chemistry* / Q000302:isolation & purification; D007624:KB Cells; D007814:Larva; D007941:Leukemia P388; D009682:Magnetic Resonance Spectroscopy; D008519:Medicine, Traditional; D008800:Mexico; D051379:Mice; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D010936:Plant Extracts; D010946:Plants, Medicinal; D013055:Spectrophotometry, Infrared; D018411:Spodoptera; D014407:Tumor Cells, Cultured
D000480:Alkynes; D000900:Anti-Bacterial Agents; D000972:Antineoplastic Agents, Phytogenic; D005960:Glucosides; D007306:Insecticides; D010936:Plant Extracts