Glioblastoma multiforme in the left frontal lobe subsequent to malignant lymphoma in the right orbit.
A 62-year-old male presented with glioblastoma multiforme in the left frontal lobe manifesting as motor aphasia, subsequent to a malignant lymphoma in the right orbit. He underwent subtotal removal of the right orbital mass presenting as right exophthalmos which was shown by histological examination to be non-Hodgkin's lymphoma. He received 30 Gy Lineac irradiation to the right orbit. His post-operative course was satisfactory. Magnetic resonance (MR) imaging with gadolinium-diethylenetriaminepenta-acetic acid (Gd-DTPA) 7 months later demonstrated a small spotty enhanced lesion in the left frontal lobe. He developed motor aphasia 1 year after irradiation. MR imaging disclosed an enhanced mass in the left frontal lobe, which was totally removed. Histological examination revealed glioblastoma multiforme. Patients with malignant lymphoma may develop a subsequent second malignant tumor. MR imaging with Gd-DTPA is quite useful for early detection of a second brain tumor.
Tomida
M
M
Department of Neurosurgery, Shinshiro City Hospital, Aichi.
Muraki
M
M
Hiramatsu
H
H
Tsukamoto
K
K
Hinokuma
K
K
Uemura
K
K
Masago
A
A
Ueda
Y
Y
Mabe
H
H
Kuroda
M
M
Nakamura
T
T
D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology* / Q000532:radiotherapy; D005625:Frontal Lobe / Q000473:pathology* / Q000528:radiation effects; D005909:Glioblastoma / Q000150:complications* / Q000473:pathology* / Q000532:radiotherapy; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000473:pathology* / Q000532:radiotherapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009915:Orbit / Q000473:pathology* / Q000528:radiation effects; D009918:Orbital Neoplasms / Q000150:complications* / Q000473:pathology* / Q000532:radiotherapy; D011829:Radiation Dosage