title: Frequency of skin cancer and other ultraviolet radiation provoked skin lesions of eyelid and periocular region in the 1981-1992 period.
abstract: It is well known that the region of eyelids and periocular skin is exposed to ultraviolet radiation (UV rays), so it is the location of skin changes associated with the effects of this radiation. The analysis of basal cell carcinomas, keratoses, keratoacanthomas and cornu cutaneum of this regions covered a 12-year period. In the total of 1,398 skin biopsies from the Department of Ophthalmology, Sestre Milosrdnice University Hospital from Zagreb, the above mentioned lesions were found in 498 cases. Most frequent were basal cell carcinomas (BCC), found in 377 cases, followed by squamous cell carcinoma (SCC) in 64, keratoses in 37, cornu cutaneum in 8 and keratoacanthoma in 12 cases. As BCC was the most frequent finding in the bioptic material from this clinic, special emphasis was put on this tumor, its age and sex distribution, and localization. In the discussion and material analysis, particular reference is given to the causative relation with the effects of UV radiation. As a special contribution to the discussion on the connection of these changes with UV radiation, 3 cases with the occurrence of BCC and seborrheic keratoses in the same lesion and a patient with senile elastosis and BCC in the same segment of the skin of an eyelid are described.
authors.affiliation: Ljudevit Jurak Department of Clinical Pathology, Sestre Milosrdnice University Hospital, Zagreb, Croatia.
authors.forename: J
authors.initials: J
authors.lastname: Talan-Hranilović
authors.forename: V
authors.initials: V
authors.lastname: Cajkovac
authors.forename: T
authors.initials: T
authors.lastname: Gregurek-Novak
authors.forename: S
authors.initials: S
authors.lastname: Padovan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000453:epidemiology; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology; D017523:Croatia / Q000453:epidemiology; D005142:Eyelid Neoplasms / Q000453:epidemiology*; D005153:Facial Neoplasms / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology*; D015995:Prevalence; D012189:Retrospective Studies; D012871:Skin Diseases / Q000453:epidemiology; D014466:Ultraviolet Rays / Q000009:adverse effects*