A phase I study of an adeno-associated virus-CFTR gene vector in adult CF patients with mild lung disease.
Flotte
T
T
Carter
B
B
Conrad
C
C
Guggino
W
W
Reynolds
T
T
Rosenstein
B
B
Taylor
G
G
Walden
S
S
Wetzel
R
R
D000293:Adolescent; D000328:Adult; D000818:Animals; D002460:Cell Line; D002985:Clinical Protocols; D003550:Cystic Fibrosis / Q000150:complications / Q000628:therapy*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics*; D000229:Dependovirus / Q000235:genetics*; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D015316:Genetic Therapy / Q000009:adverse effects; D005822:Genetic Vectors; D006801:Humans; D008171:Lung Diseases / Q000209:etiology / Q000628:therapy*; D008253:Macaca mulatta; D011817:Rabbits; D018570:Risk Assessment
C505032:CFTR protein, human; D019005:Cystic Fibrosis Transmembrane Conductance Regulator