title: The influence of age on the severity of peritonitis.
abstract: OBJECTIVE
  To evaluate the influence of age on the evolution and severity of peritonitis.
  
  
  METHODS
  A chart review.
  
  
  METHODS
  An adult university hospital.
  
  
  METHODS
  One hundred and twenty-two patients with acute appendicitis and 100 patients with acute colonic diverticulitis requiring operation or percutaneous drainage.
  
  
  METHODS
  Patient age and sex, presence of perforation or gangrene (appendicitis), extent of peritonitis (diverticulitis); duration of symptoms prior to admission; admission leukocyte count; duration of hospitalization before surgery; length of hospital stay; and death rate.
  
  
  RESULTS
  Patients with acute appendicitis who were aged 65 years or older were three times more likely than younger patients to have a gangrenous or perforated appendix (odds ratio 3.1, 95% confidence interval 1.1 to 8.4, p < 0.05); older patients with perforated diverticulitis were three times more likely than younger patients to have generalized peritonitis than localized (pericolic or pelvic) peritonitis (odds ratio 2.9, 95% confidence interval 1.2 to 7.5, p < 0.05).
  
  
  CONCLUSIONS
  These findings are consistent with the hypothesis that the biologic features of peritonitis differ in the elderly, who are more likely to present with an advanced or severe process than young patients.
authors.affiliation: Department of Surgery, University of Ottawa, Ont.
authors.forename: J M
authors.initials: JM
authors.lastname: Watters
authors.forename: J M
authors.initials: JM
authors.lastname: Blakslee
authors.forename: R J
authors.initials: RJ
authors.lastname: March
authors.forename: M L
authors.initials: ML
authors.lastname: Redmond
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001064:Appendicitis / Q000175:diagnosis / Q000453:epidemiology*; D016022:Case-Control Studies; D004239:Diverticulitis, Colonic / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007416:Intestinal Perforation / Q000175:diagnosis / Q000453:epidemiology; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D010538:Peritonitis / Q000175:diagnosis / Q000453:epidemiology*; D012422:Rupture, Spontaneous / Q000175:diagnosis / Q000453:epidemiology; D012720:Severity of Illness Index; D012737:Sex Factors