title: Capillary electrophoresis analysis of chemical warfare agent breakdown products. I. Counterelectroosmotic separation of alkylphosphonic acids and their monoester derivatives.
abstract: An analytical method has been developed for the analysis of chemical warfare agents by capillary zone electrophoresis (CZE). Sorbate anion has been selected as indirect UV-absorbing agent and decamethonium cation reduces the electroosmotic flow. The optimized electrolyte (5 mM sorbic acid, 0.1 mM decamethonium bromide pH 6) allows the simultaneous separation of alkylphosphonic acids and their monoester derivatives in less than 15 min. The measurement of phosphonic solutes has been achieved in spiked soils using calibration curves in the 5-50 mg/l concentration range.
authors.affiliation: Université d'Orléans, Institut de Chimie Organique et Analytique, URA 499, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Mercier
authors.forename: P
authors.initials: P
authors.lastname: Morin
authors.forename: M
authors.initials: M
authors.lastname: Dreux
authors.forename: A
authors.initials: A
authors.lastname: Tambute
mesh_terms: D000478:Alkylation; D000838:Anions; D002618:Chemical Warfare; D003650:Decamethonium Compounds; D019075:Electrophoresis, Capillary / Q000379:methods*; D004952:Esters / Q000302:isolation & purification; D006863:Hydrogen-Ion Concentration; D007202:Indicators and Reagents; D063065:Organophosphonates / Q000302:isolation & purification*; D013011:Sorbic Acid
chemical_list: D000838:Anions; D003650:Decamethonium Compounds; D004952:Esters; D007202:Indicators and Reagents; D063065:Organophosphonates; C033019:decamethonium; D013011:Sorbic Acid