Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritis.
Evans
C H
CH
Department of Molecular Genetics & Biochemistry, University of Pittsburgh School of Medicine, USA.
Robbins
P D
PD
Ghivizzani
S C
SC
Herndon
J H
JH
Kang
R
R
Bahnson
A B
AB
Barranger
J A
JA
Elders
E M
EM
Gay
S
S
Tomaino
M M
MM
Wasko
M C
MC
Watkins
S C
SC
Whiteside
T L
TL
Glorioso
J C
JC
Lotze
M T
MT
Wright
T M
TM
D001172:Arthritis, Rheumatoid / Q000628:therapy*; D017690:Cell Transplantation; D002985:Clinical Protocols; D005240:Feasibility Studies; D018014:Gene Transfer Techniques; D015316:Genetic Therapy / Q000379:methods; D006801:Humans; D053590:Interleukin 1 Receptor Antagonist Protein; D007375:Interleukin-1 / Q000037:antagonists & inhibitors*; D008662:Metacarpophalangeal Joint; D012795:Sialoglycoproteins / Q000235:genetics* / Q000627:therapeutic use; D013582:Synovial Fluid / Q000166:cytology
C507763:IL1RN protein, human; D053590:Interleukin 1 Receptor Antagonist Protein; D007375:Interleukin-1; D012795:Sialoglycoproteins