title: Investigation of an outbreak of foot-and-mouth disease in vaccinated dairy cattle in Thailand.
abstract: An outbreak of foot-and-mouth disease that spread between two related vaccinated dairy herds was investigated. Although the cattle were of similar vaccination status, in one herd there was high morbidity, whereas in the other there was considerably lower morbidity. The relationship between the vaccine virus and the outbreak virus was expressed as an r value determined by the two-dimensional neutralisation test. Bovine serum homologous to the vaccine virus indicated a close antigenic relationship between the vaccine virus and the outbreak virus (r = 0.61). The source of the outbreak virus was not determined. The investigation suggested a requirement for close contact between stock for foot-and-mouth disease to spread in a tropical environment, in contrast to the capacity of the disease to spread considerable distances by aerosol transmission in temperate climates.
authors.affiliation: CSIRO Australian Animal Health Laboratory, Geelong, Victoria.
authors.forename: L J
authors.initials: LJ
authors.lastname: Gleeson
authors.forename: P
authors.initials: P
authors.lastname: Chamnanpood
authors.forename: S
authors.initials: S
authors.lastname: Cheunprasert
authors.forename: N
authors.initials: N
authors.lastname: Srimasartitkol
authors.forename: A
authors.initials: A
authors.lastname: Trisasarom
mesh_terms: D000818:Animals; D005537:Aphthovirus / Q000276:immunology*; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control / Q000821:virology; D004196:Disease Outbreaks / Q000662:veterinary*; D005260:Female; D005536:Foot-and-Mouth Disease / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control / Q000821:virology; D008297:Male; D013785:Thailand / Q000453:epidemiology; D017211:Treatment Failure; D014765:Viral Vaccines / Q000008:administration & dosage*
chemical_list: D014765:Viral Vaccines