[Endogenous regulators of long-term potentiation and depression in slices of the olfactory cortex in rats].
Two fractions of the perfusate collected during tetanic stimulation of the rat lateral olfactory tract, were studied. The > 50 kDa fractions induced a long-term depression of focal potentials, whereas the < 50 fractions mainly induced an activation. The findings suggest a release of a number of neurohumoral substances by the donor cells during tetanisation, the substances being polypeptides, most probably, modulating the synaptic plasticity.
Mokrushin
A A
AA
Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg.
Tokarev
A V
AV
D000818:Animals; D003864:Depression, Chemical; D066298:In Vitro Techniques; D017774:Long-Term Potentiation / Q000187:drug effects / Q000502:physiology*; D008970:Molecular Weight; D018377:Neurotransmitter Agents / Q000032:analysis / Q000302:isolation & purification / Q000494:pharmacology / Q000502:physiology*; D009833:Olfactory Pathways / Q000187:drug effects / Q000502:physiology*; D010477:Perfusion; D051381:Rats; D013268:Stimulation, Chemical; D014462:Ultrafiltration
D018377:Neurotransmitter Agents
Endogennye reguliatory dolgovremennoĭ potentsiatsii i depressii v srezakh oboniatel'noĭ kory mozga krys.