title: Synthesis and anti-inflammatory evaluation of new sulfamoylheterocarboxylic derivatives.
abstract: A series of new sulfamoylthiophene and sulfamoylpyrazole carboxylic acid derivatives was synthesized. Some of these compounds show interesting analgesic properties and significant nonsteroidal anti-inflammatory activities in several models of inflammation.
authors.affiliation: Instituto de Química Médica, CSIC, Madrid, Spain.
authors.forename: J A
authors.initials: JA
authors.lastname: Díaz
authors.forename: M E
authors.initials: ME
authors.lastname: Morante
authors.forename: S
authors.initials: S
authors.lastname: Vega
authors.forename: V
authors.initials: V
authors.lastname: Darias
authors.forename: S
authors.initials: S
authors.lastname: Abdala
authors.forename: L
authors.initials: L
authors.lastname: Delgado
authors.forename: B
authors.initials: B
authors.lastname: de las Heras
authors.forename: A
authors.initials: A
authors.lastname: Villar
authors.forename: J M
authors.initials: JM
authors.lastname: Vivas
mesh_terms: D000700:Analgesics / Q000138:chemical synthesis / Q000494:pharmacology; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D001777:Blood Coagulation / Q000187:drug effects; D002264:Carboxylic Acids / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D005260:Female; D066298:In Vitro Techniques; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D009125:Muscle Relaxants, Central / Q000138:chemical synthesis / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D002264:Carboxylic Acids; D009125:Muscle Relaxants, Central