Pathophysiology of ion channel mutations.
The past year has seen significant advances in our understanding of ion channel disorders. The highlights of these advances include a detailed delineation of the molecular mechanisms underlying inherited cardiac arrhythmias and the discovery that ion channel mutations can contribute to neural development and neurodegeneration.
Keating
M T
MT
Howard Hughes Medical Institute, University of Utah, Salt Lake City 84112, USA.
Sanguinetti
M C
MC
D000818:Animals; D001145:Arrhythmias, Cardiac / Q000503:physiopathology; D004573:Electrolytes; D006706:Homeostasis; D006801:Humans; D015640:Ion Channel Gating; D007473:Ion Channels / Q000235:genetics*; D008024:Ligands; D009154:Mutation; D009410:Nerve Degeneration; D009474:Neurons; D014867:Water
D004573:Electrolytes; D007473:Ion Channels; D008024:Ligands; D014867:Water