The cytotoxicity of psoralidin from Psoralea corylifolia.
A cytotoxic coumestan derivative, psoralidin (1), was isolated from the seed of Psoralea corylifolia. The IC50 values of 1 against SNU-1 and SNU-16 carcinoma cell lines were 53 and 203 micrograms/ml, respectively, indicating cytotoxic activity against stomach carcinoma cell lines.
Yang
Y M
YM
Hyun
J W
JW
Sung
M S
MS
Chung
H S
HS
Kim
B K
BK
Paik
W H
WH
Kang
S S
SS
Park
J G
JG
D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000633:toxicity; D001572:Benzofurans / Q000302:isolation & purification* / Q000633:toxicity; D002470:Cell Survival / Q000187:drug effects; D003374:Coumarins / Q000302:isolation & purification* / Q000633:toxicity; D005047:Etoposide / Q000633:toxicity; D006801:Humans; D010946:Plants, Medicinal; D012639:Seeds; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D001572:Benzofurans; D003374:Coumarins; D005047:Etoposide; C102768:psoralidin