title: [Mobile blood gas and laboratory monitoring. A new technology in clinical routine].
abstract: BACKGROUND
  Decision-making on therapy in acute cases involves clinical examination and monitoring of vital parameters and fluid balance; especially, however, laboratory parameters. The present study compared the results of a new bedside laboratory analysis system (PortLab, i-STAT Corp., Princeton NJ) with the analytical results obtained in our central laboratory. In a second phase personnel costs and turnover times of the two methods were evaluated comparatively.
  
  
  METHODS
  The PortLab system consists of a basic unit (539 g) with an integrated display and disposable silicon cartridges with thin-film electrodes. Up to 8 parameters can be determined simultaneously in 60 microliters of whole blood. Fifty results obtained with the PortLab system of the parameters sodium, potassium, chlorid, glucose, BUN, hematocrit, the calculated haemoglobin and blood gas analysis were correlated with the results obtained by central laboratory analysis. In a second phase, all procedural steps, the time needed and the turnover times for laboratory analysis were compared with the expenditure for the same analyses performed with the PortLab system.
  
  
  CONCLUSIONS
  The results obtained using PortLab analysis correlated very well with those of the central laboratory (between 0.966 for the hematocrit and 0.994 for pO2). Three steps were required to perform bedside analysis with the PortLap system. The staff was occupied for 1 min. and 15 sec. and the results were ready within 4 min. and 45 sec. (pure analysis time < 2 min.). Analysis in the central laboratory required 8 steps, the intensive care staff was occupied for 6 min. and 15 sec., 5 min. and 15 sec. of which they were away from the patients' side. Analysis of blood gases required 4 steps, the result was ready in 4 min. 15 sec. The personnel was occupied for an equally long time. The use of PortLab saved personnel resources of 5 minutes per laboratory analysis and 3 minutes per blood gas analysis.
  
  
  CONCLUSIONS
  The PortLab system proved easy to handle and reliable. Valuable personnel resources can be saved. This method cannot replace conventional laboratory analyses, but enables more extensive monitoring of patients and their laboratory parameters. The industry should develop analogous monitoring systems for modular solutions.
authors.affiliation: Klinik für Anästhesiologie und operative Intensivmedizin, Klinik am Eichert Göppingen.
authors.forename: J
authors.initials: J
authors.lastname: Martin
authors.forename: M
authors.initials: M
authors.lastname: Messelken
authors.forename: J
authors.initials: J
authors.lastname: Hiller
authors.forename: R
authors.initials: R
authors.lastname: Dieterle-Paterakis
authors.forename: C
authors.initials: C
authors.lastname: Krier
authors.forename: P
authors.initials: P
authors.lastname: Milewski
mesh_terms: D001774:Blood Chemical Analysis / Q000191:economics / Q000295:instrumentation*; D001784:Blood Gas Analysis / Q000191:economics / Q000295:instrumentation*; D002405:Catheterization, Central Venous / Q000295:instrumentation; D003362:Cost-Benefit Analysis; D003422:Critical Care / Q000191:economics; D004867:Equipment Design; D006801:Humans; D008991:Monitoring, Physiologic / Q000191:economics / Q000295:instrumentation*; D019095:Point-of-Care Systems / Q000191:economics; D011237:Predictive Value of Tests; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D012984:Software
vernacular_title: Mobiles Blutgas- und Labormonitoring. Eine neue Technologie in der klinischen Routine.