Is t(6;14) a non-random translocation in childhood acute mixed lineage leukemia?
We report a case of childhood acute mixed lineage leukemia (AMLL) with a translocation t(6;14)(q25;q32) as the main clonal abnormality. A comparison of this case with another one with similar cytogenetics and clinical findings may suggest that t(6;14)(q25;q32) is a non-random occurrence in childhood AMLL.
Batanian
J R
JR
Pediatrics Department, Saint Louis University Hospital, Missouri, USA.
Dunphy
C H
CH
Gale
G
G
Havlioglu
N
N
D000208:Acute Disease; D000293:Adolescent; D001853:Bone Marrow / Q000473:pathology; D002883:Chromosomes, Human, Pair 14 / Q000648:ultrastructure*; D002896:Chromosomes, Human, Pair 6 / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D017404:In Situ Hybridization, Fluorescence; D015456:Leukemia, Biphenotypic, Acute / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic