[Experimental data on bases of MAC of piroxicam in the air of workplace].
The experiments on white rats, mice, guinea pigs, rabbits studied inhalation toxicity of piroxicam. The substance having strong cumulation (Jcum = 0.5) and embryotoxic effects (Limap = 0.1 mg/cum) is assigned to a group of parenchymatous poisons. Toxicometry data (CL50 = 250 mg/cum, Limac = 50 mg/cum, Limch = 0.5 mg/cum) prove the first jeopardy grade of the substance. The recommended MAC for workplace is 0.05 mg/cum.
Bogachuk
G P
GP
Barkova
N P
NP
Andropova
S N
SN
Gushchina
A A
AA
Portianoĭ
A A
AA
D000395:Air Pollutants, Occupational / Q000633:toxicity*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000633:toxicity*; D004345:Drug Industry; D006168:Guinea Pigs; D008452:Maximum Allowable Concentration; D051379:Mice; D010894:Piroxicam / Q000633:toxicity*; D011817:Rabbits; D051381:Rats
D000395:Air Pollutants, Occupational; D000894:Anti-Inflammatory Agents, Non-Steroidal; D010894:Piroxicam
Eksperimental'nye dannye k obosnovaniiu PDK piroksikama v vozdukhe rabocheĭ zony.