title: Tissue polypeptide antigen during parturition and puerperium.
abstract: The tumour and cytoskeleton protein tissue polypeptide antigen (TPA) was determined in maternal serum taken during the second stage of labour and on the 4th postpartum day. Pregnant women at term (weeks 38-42) served as a control group. TPA levels of women during parturition (median 169 U/l) were higher than those of the control group (median 108.5 U/l) and those of women on the 4th postpartum day (median 66.5 U/l); p < 0.0001 in each case. The correlation between duration of labour and TPA concentration was positive and significant (rs = 0.3; p = 0.03). A significant negative correlation was found between placental weight and maternal serum TPA levels during parturition (rs = -0.3; p = 0.03). The decline of TPA after delivery indicated a serum half-life for TPA of less than 4 days.
authors.affiliation: Department of Obstetrics and Gynecology, University of Innsbruck, Austria.
authors.forename: A
authors.initials: A
authors.lastname: Bergant
authors.forename: H
authors.initials: H
authors.lastname: Kirchler
authors.forename: H
authors.initials: H
authors.lastname: Schröcksnadel
authors.forename: G
authors.initials: G
authors.lastname: Daxenbichler
mesh_terms: D005260:Female; D006207:Half-Life; D006801:Humans; D007743:Labor, Obstetric / Q000276:immunology*; D008297:Male; D049590:Postpartum Period / Q000276:immunology*; D011247:Pregnancy; D012016:Reference Values; D019396:Tissue Polypeptide Antigen / Q000097:blood*
chemical_list: D019396:Tissue Polypeptide Antigen