Immunology: keeping mother at bay.
Like its better-known polymorphic relatives, HLA-G, a relatively unpolymorphic class I MHC molecule expressed by fostal trophoblast cells, binds short peptides with a defined sequence motif; HLA-G may play an important role in maternal tolerance to a fostus.
Parham
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Department of Structural Biology, Stanford University, California 94305, USA.
D000818:Animals; D001665:Binding Sites; D006680:HLA Antigens / Q000276:immunology*; D059951:HLA-G Antigens; D015395:Histocompatibility Antigens Class I / Q000276:immunology*; D006801:Humans; D009035:Mothers; D010455:Peptides / Q000276:immunology*
D006680:HLA Antigens; D059951:HLA-G Antigens; D015395:Histocompatibility Antigens Class I; D010455:Peptides