title: [Functional outcome of laparoscopically transposed ovaries in the multidisciplinary treatment of cervical cancers. Analysis of risk factors].
abstract: OBJECTIVE
  To evaluate the place of ovarian transposition by laparoscopy in the treatment of cervical cancers.
  
  
  METHODS
  From March 1992 to November 1994 at Institut Bergonié, 11 patients (mean age: 40 years; 36-44 years) with invasive squamous cell carcinoma of the uterine cervix stages Ib (4 cases) and IIb (7 cases) underwent lateral high ovarian transposition by laparoscopy performed during a staging inter-iliacal lymphadenectomy. There was no complication during surgery but one phlebitis occurred postoperatively. The treatment for the cervical cancer included: brachytherapy (11 cases), external beam radiotherapy (EBRT) (9 cases), surgery (6 cases), chemotherapy (2 cases). Ovarian radiation dosis was calculated and hormonal status assessed.
  
  
  RESULTS
  Ovarian preservation was achieved in 30% of the cases. The mean lowest cumulative dosis to the ovaries was 1.78 Gy. Age was the most predictive factor for ovarian preservation.
  
  
  CONCLUSIONS
  With ovarian laparoscopic transposition, ovarian function can be preserved in selected patients requiring first line radiotherapy for cancer of the cervix. After the age of 40 years, transposition should be restricted to small T1 tumors treated by brachytherapy. When EBRT is required for larger lesions, transposition should be reserved to younger patients.
authors.affiliation: Institut Bergonié, Centre Régional de Lutte Contre le Cancer, Bordeaux.
authors.forename: E
authors.initials: E
authors.lastname: Stöckle
authors.forename: G
authors.initials: G
authors.lastname: Verdier
authors.forename: L
authors.initials: L
authors.lastname: Thomas
authors.forename: E
authors.initials: E
authors.lastname: Bussières
authors.forename: A
authors.initials: A
authors.lastname: Avril
authors.forename: F
authors.initials: F
authors.lastname: Lakdja
authors.forename: J
authors.initials: J
authors.lastname: Pigneux
authors.forename: J
authors.initials: J
authors.lastname: Chauvergne
mesh_terms: D000328:Adult; D001918:Brachytherapy; D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D010535:Laparoscopy / Q000379:methods; D010053:Ovary / Q000637:transplantation*; D011879:Radiotherapy Dosage; D018714:Radiotherapy, Adjuvant; D016042:Transplantation, Heterotopic / Q000379:methods; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000601:surgery*
vernacular_title: Avenir fonctionnel des ovaires transposés par coelioscopie dans le traitement multidisciplinaire des cancers du col utérin. Analyse des facteurs de risque.