title: Measurement of periprosthetic bone density in hip arthroplasty using dual-energy x-ray absorptiometry. Reproducibility of measurements.
abstract: To define the precision (reproducibility) of measurement of periprosthetic bone mineral density and bone mineral content, dual-energy x-ray absorptiometry scans were obtained on 45 randomly selected patients who had had a unilateral total hip arthroplasty within the previous 3 years. The coefficients of variation of the bone mineral density in the proximal Gruen zones were 5.0 and 5.3%, corresponding to errors of 0.07 and 0.11 g/cm2. The coefficients of variation of the bone mineral density for the distal zones averaged 2.8%, with an error of 0.08 g/cm2. The coefficients of variation of the bone mineral content were 4.8 and 2.9% for the proximal and distal zones. The contralateral femur was also scanned in 32 of the patients. For the contralateral femur bone mineral density, the coefficients of variation were 5.0% for the proximal zones and 4.8% for the distal zones. The bone mineral content was 6.0% for the contralateral regions. These results imply that differences in bone mineral density greater than 0.16 g/cm2 (2 standard errors) can be reliably measured. Dual-energy x-ray absorptiometry therefore provides a highly reproducible technique for quantitatively monitoring the changes in bone density that occur after total hip arthroplasty.
authors.affiliation: Department of Nuclear Medicine, St. George Hospital, Kogarah, NSW, Australia.
authors.forename: R C
authors.initials: RC
authors.lastname: Smart
authors.forename: S
authors.initials: S
authors.lastname: Barbagallo
authors.forename: G L
authors.initials: GL
authors.lastname: Slater
authors.forename: R S
authors.initials: RS
authors.lastname: Kuo
authors.forename: S P
authors.initials: SP
authors.lastname: Butler
authors.forename: R P
authors.initials: RP
authors.lastname: Drummond
authors.forename: R
authors.initials: R
authors.lastname: Sekel
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D005260:Female; D005269:Femur / Q000737:chemistry*; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D016348:Osseointegration; D011897:Random Allocation; D015203:Reproducibility of Results