title: [Mutational analysis and genetic cloning of the agnostic locus controlling learning ability in Drosophila].
abstract: The ts-mutations of the agnostic gene either increased or decreased the activity of the AC and PDE. A chromosomal deficiency in the 11B region failed to complement with the agnostic behavioral defect like agn P29 and P40, led to an increased proportion of the PDE-1 in total PDE and to the structural defects in the central complex thus indicating that the P insertion is responsible for the mutant agnostic phenotype.
authors.affiliation: Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg.
authors.forename: A I
authors.initials: AI
authors.lastname: Peresleni
authors.forename: E V
authors.initials: EV
authors.lastname: Savvateeva
authors.forename: I V
authors.initials: IV
authors.lastname: Peresleni
authors.forename: L M
authors.initials: LM
authors.lastname: Sharagina
mesh_terms: D000818:Animals; D003001:Cloning, Molecular / Q000379:methods; D000242:Cyclic AMP / Q000378:metabolism; D004252:DNA Mutational Analysis; D004251:DNA Transposable Elements / Q000235:genetics / Q000502:physiology; D004331:Drosophila melanogaster; D005260:Female; D005796:Genes / Q000235:genetics* / Q000502:physiology; D005824:Genetics, Behavioral; D006579:Heterozygote; D007858:Learning / Q000502:physiology*; D008297:Male; D009154:Mutation / Q000235:genetics / Q000502:physiology; D010641:Phenotype; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism; D014960:X Chromosome / Q000235:genetics / Q000502:physiology
chemical_list: D004251:DNA Transposable Elements; D000242:Cyclic AMP; D010727:Phosphoric Diester Hydrolases
vernacular_title: Mutatsionnyĭ analiz i geneticheskoe klonirovanie lokusa agnostic, kontroliruiuschego sposobnost'k obucheniiu, u drozofily.