[Tumor of the peripheral nerve sheath with rhabdomyoblastic differentiation arising in a ganglioneuroma: neurilemmoma? A fortuitously detected case].
An otherwise healthy 21-year-old man with no evidence or family history of Von Recklinghausen's neurofibromatosis presented a posterior mediastinal mass detected on routine chest radiographs. The findings of standard light microscopy, ultrastructural examination and immunohistochemical studies suggested the working hypothesis of an unusual malignant "Triton" tumour: -arising in a pre-existing de novo ganglioneuroma; -fortuitously detected; -predominantly made of multinucleated spindle cells with only ultrastructural and immunohistochemical rhabdomyoblastic differentiation.
Grippari
J L
JL
Service d'Anatomie et Cytologie Pathologiques, Hôpital d'Instruction des Armées du Val-de-Grâce, Paris.
Neveux
Y
Y
Arborio
M
M
Jancovici
R
R
Cosnard
G
G
de Saint Maur
P P
PP
Schill
H
H
D000328:Adult; D002454:Cell Differentiation / Q000502:physiology; D003937:Diagnosis, Differential; D005729:Ganglioneuroma / Q000473:pathology*; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000473:pathology*; D018317:Nerve Sheath Neoplasms / Q000473:pathology*; D009442:Neurilemmoma / Q000473:pathology*; D010524:Peripheral Nervous System Neoplasms / Q000473:pathology*
Tumeur des gaines des nerfs périphériques à différenciation musculaire survenant sur un ganglioneurome: tumeur de Triton?