Lung cancer in nonsmoking Chinese women: a case-control study.
The risk factors for lung cancer in lifetime nonsmoking women were investigated in a hospital-based case-control study in the urban area of Shenyang, China, between April 1992 and May 1994. One-hundred thirty-five newly-diagnosed lung cancer cases and an equal number of controls, matched for age and sex, were enrolled and interviewed by trained personnel who administered a standardized questionnaire. The histopathological cell type was predominantly adenocarcinoma (54.5%), followed by small cell carcinoma (20%), squamous cell carcinoma (16.4%), and others (9.1%). The data were analyzed using the Mantel-Haenszel method and by multivariate logistic regression analysis. The odds ratio (OR) and confidence interval (CI) associated with cooking oil vapors and with family history of cancer were 3.79 (95% CI, 2.29-6.27) and 2.29 (95% CI, 1.01-5.17), respectively. No association was found between exposure to environmental tobacco smoke (ETS), presence of previous lung diseases, and "kang" use. Cooking practices, exposure to cooking fumes, and a family history of cancer were found to significantly increase the risk of lung cancer.
Wang
T J
TJ
China Medical University, Shenyang, China.
Zhou
B S
BS
Shi
J P
JP
D000328:Adult; D000368:Aged; D016902:Air Pollution, Indoor / Q000009:adverse effects*; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D016015:Logistic Models; D008175:Lung Neoplasms / Q000453:epidemiology / Q000209:etiology*; D008875:Middle Aged; D016017:Odds Ratio; D012307:Risk Factors; D014028:Tobacco Smoke Pollution / Q000009:adverse effects*
D014028:Tobacco Smoke Pollution