title: Anti-Hu antibody in a patient with Lambert-Eaton myasthenic syndrome and early detection of small cell lung cancer.
abstract: We report a patient with Lambert-Eaton myasthenic syndrome (LEMS) and anti-Hu antibody, which was an important clue in detecting small cell lung cancer (SCLC) at the early stage. This patient had no symptoms of anti-Hu associated paraneoplastic neurological syndrome. In LEMS patients in whom conventional tests fail to detect malignancy, anti-Hu antibody should be evaluated to diagnose SCLC at the early stage.
authors.affiliation: Department of Neurology, Kitasato University East Hospital, Sagamihara.
authors.forename: K
authors.initials: K
authors.lastname: Tomiyasu
authors.forename: H
authors.initials: H
authors.lastname: Ito
authors.forename: N
authors.initials: N
authors.lastname: Kanazawa
authors.forename: T
authors.initials: T
authors.lastname: Saito
authors.forename: H
authors.initials: H
authors.lastname: Kowa
mesh_terms: D000368:Aged; D000974:Antibodies, Antinuclear / Q000097:blood*; D001426:Bacterial Proteins / Q000097:blood*; D018288:Carcinoma, Small Cell / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D004268:DNA-Binding Proteins / Q000097:blood*; D006801:Humans; D007150:Immunohistochemistry; D015624:Lambert-Eaton Myasthenic Syndrome / Q000097:blood / Q000276:immunology*; D008175:Lung Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000276:immunology; D008297:Male
chemical_list: D000974:Antibodies, Antinuclear; D001426:Bacterial Proteins; D004268:DNA-Binding Proteins; C040330:histone-like protein HU, bacteria