Magnetic field tomography of cortical and deep processes: examples of "real-time mapping" of averaged and single trial MEG signals.
Magnetic field tomography (MFT) provides 3-dimensional estimates of brain activity, from non-contact, non-invasive measurements of the magnetic field generated by coherent electrical activity in the brain. MFT analysis of averaged auditory "odd-ball" data show cortical and deep activation, presumably from the amygdala and hippocampus. These results are compared with MFT estimates obtained from a patient who had undergone lobectomy which removed these structures. The variability from subject to subject is confounded by variability between trials for the same subject; the relationship between the averaged and single trials is probed by bi-hemispheric simultaneous measurements performed under the same odd-ball paradigm and by MFT analysis of auditory evoked data and interictal epileptic activity.
Ioannides
A A
AA
Department of Physics, Open University, Milton Keynes, UK.
Liu
M J
MJ
Liu
L C
LC
Bamidis
P D
PD
Hellstrand
E
E
Stephan
K M
KM
D000161:Acoustic Stimulation; D000328:Adult; D001921:Brain / Q000502:physiology* / Q000503:physiopathology; D002540:Cerebral Cortex / Q000502:physiology* / Q000503:physiopathology; D003199:Computer Systems; D004827:Epilepsy / Q000503:physiopathology; D005072:Evoked Potentials, Auditory / Q000502:physiology; D006801:Humans; D015225:Magnetoencephalography / Q000295:instrumentation; D008297:Male; D014054:Tomography