title: Morbidity and mortality in 602 patients with acute pancreatitis seen between the years 1980-1994.
abstract: The course of a first attack of acute pancreatitis was evaluated in a retrospective study of 602 patients, who were admitted between 01.01.1980 and 30.09.1993 to the Centers of Internal Medicine and Surgery of the University of Göttingen (n = 417) and from 16.11.1986 to 30.06.1994 to the Municipal Hospital of Lüneburg (n = 185). Etiology was biliary tract disease in 227 (37.7%), alcohol abuse in 177 (29.4%), unknown in 133 (22.1%), and other causes in 65 (10.8%) patients. Mean hospital stay was 27.9 +/- 24 days (x +/- SD), median 23 days. Pancreatic pseudocysts developed in 14.3% of the patients, and surgical treatment was necessary in 11.1%. Within the first 48 hours, respiratory insufficiency was observed in 63.2% of the 204 patients undergoing arterial blood gas analysis while renal impairment occurred in 32.6% of 602 patients. Artificial ventilation was indicated in 12.5%, and dialysis in 7% of the patients. Mortality rate was 6.1%, correlating significantly with respiratory and renal impairment and procedures in connection with these complications and also with transfers from other hospitals.
authors.affiliation: Department of Internal Medicine, Municipal of Hospital of Lüneburg, Germany.
authors.forename: P G
authors.initials: PG
authors.lastname: Lankisch
authors.forename: S
authors.initials: S
authors.lastname: Burchard-Reckert
authors.forename: M
authors.initials: M
authors.lastname: Petersen
authors.forename: D
authors.initials: D
authors.lastname: Lehnick
authors.forename: C A
authors.initials: CA
authors.lastname: Schirren
authors.forename: H
authors.initials: H
authors.lastname: Köhler
authors.forename: F
authors.initials: F
authors.lastname: Stöckmann
authors.forename: H J
authors.initials: HJ
authors.lastname: Peiper
authors.forename: W
authors.initials: W
authors.lastname: Creutzfeldt
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D002423:Cause of Death; D003422:Critical Care / Q000706:statistics & numerical data; D003430:Cross-Sectional Studies; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D010192:Pancreatic Pseudocyst / Q000209:etiology / Q000401:mortality / Q000601:surgery; D010195:Pancreatitis / Q000209:etiology / Q000401:mortality* / Q000601:surgery; D012189:Retrospective Studies; D015996:Survival Rate