Fatalities associated with ingestion of diethylene glycol-contaminated glycerin used to manufacture acetaminophen syrup--Haiti, November 1995-June 1996.
From November 1995 through June 1996, acute anuric renal failure was diagnosed in 86 children (aged 3 months-13 years) in Haiti; most (85%) children were aged < or = 5 years. On June 14, 1996, a joint investigation was initiated by the Ministry of Health of Haiti, the University General Hospital in Port-au-Prince, the Pan American Health Organization/World Health Organization, the Caribbean Epidemiology Center, and CDC. This report summarizes the preliminary findings of this ongoing investigation, which indicate that this outbreak was associated with diethylene glycol (DEG)-contaminated glycerin used to manufacture acetaminophen syrup.
D000082:Acetaminophen / Q000008:administration & dosage; D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000401:mortality; D000284:Administration, Oral; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D004340:Drug Contamination; D005026:Ethylene Glycols / Q000506:poisoning*; D005990:Glycerol; D006205:Haiti / Q000453:epidemiology; D006801:Humans; D007223:Infant
D005026:Ethylene Glycols; D000082:Acetaminophen; C013484:diethylene glycol; D005990:Glycerol