title: Targeted disruption of specific cytochromes P450 and xenobiotic receptor genes.
authors.affiliation: Division of Basic Science, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
authors.forename: P M
authors.initials: PM
authors.lastname: Fernandez-Salguero
authors.forename: F J
authors.initials: FJ
authors.lastname: Gonzalez
mesh_terms: D000818:Animals; D002678:Chimera; D002999:Clone Cells; D003577:Cytochrome P-450 Enzyme System / Q000235:genetics*; D018274:Electroporation; D005260:Female; D018390:Gene Targeting / Q000379:methods*; D005822:Genetic Vectors; D006579:Heterozygote; D006720:Homozygote; D008297:Male; D051379:Mice; D018345:Mice, Knockout; D008845:Microinjections; D010641:Phenotype; D011247:Pregnancy; D018336:Receptors, Aryl Hydrocarbon / Q000235:genetics; D018160:Receptors, Cytoplasmic and Nuclear / Q000235:genetics*; D011995:Recombination, Genetic; D014157:Transcription Factors / Q000235:genetics; D015262:Xenobiotics / Q000378:metabolism*
chemical_list: D018336:Receptors, Aryl Hydrocarbon; D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors; D015262:Xenobiotics; D003577:Cytochrome P-450 Enzyme System