title: Assessment of left ventricular function after radiofrequency and direct current atrioventricular node ablation.
abstract: BACKGROUND
  There is limited information available regarding the effect of catheter ablation of the antioventricular (AV) junction on left ventricular (LV) function. Both deterioration and improvement in LV function have been reported following direct current (DC) ablation of the AV junction. The deterioration of LV function following DC ablation of the AV junction may be due to the accompanying barotrauma, DC arcing and direct coagulation, or even the effects of chronic ventricular pacing. If this deterioration of LV function was a result of the accompanying effects of DC shock, the use of radiofrequency ablation (RF) should not result in deterioration of LV function.
  
  
  OBJECTIVE
  To study LV function before and after different methods of AV junction ablation and in patients with chronic ventricular pacing without AV junction ablation.
  
  
  METHODS
  This study assessed LV function in patients following RF ablation, low energy DC ablation of the AV junction and compared the results with our previously reported finding in patients who had AV junction ablation using high energy DC shock. A group of patients undergoing permanent single chamber ventricular pacemaker implantation without AV junction ablation were selected as controls.
  
  
  METHODS
  All patients were paced in the ventricle at 110 beats/minute during LV function assessment by radionuclide angiography. Global LV function and segmental wall motion abnormalities were assessed before, immediately following and three months after ablation.
  
  
  RESULTS
  In the high energy DC ablation group, a fall in global LV function (50 +/- 3.0% to 43 +/- 3.0%, p = 0.02) and impairment of segmental wall motion were detected. Low energy DC ablation resulted in segmental wall motion impairment similar to high energy DC but without affecting global ejection fraction (47.0% +/- 6.7 to 45.5% +/- 3.1, p > 0.05). Neither RF ablation (44.0% +/- 3.3 to 45.3% +/- 3.5, p > 0.05), nor chronic pacing (46.7% +/- 4.9 to 47.0% +/- 2.9 p > 0.05) had any effect on global or segmental LV function.
  
  
  CONCLUSIONS
  Low energy DC or RF ablation of the AV junction does not affect global LV ejection fraction. The deterioration of global LV function after high energy DC shock ablation appears to be related to the accompanying effects of DC energy and not to the effects of chronic ventricular pacing.
authors.affiliation: Department of Cardiology, Royal Melbourne Hospital, Vic.
authors.forename: J
authors.initials: J
authors.lastname: Wong
authors.forename: J
authors.initials: J
authors.lastname: Vohra
authors.forename: W
authors.initials: W
authors.lastname: Chan
authors.forename: H G
authors.initials: HG
authors.lastname: Mond
authors.forename: M
authors.initials: M
authors.lastname: Lichtenstein
authors.forename: L
authors.initials: L
authors.lastname: Kritharides
authors.forename: R J
authors.initials: RJ
authors.lastname: Warren
mesh_terms: D000328:Adult; D000368:Aged; D001283:Atrioventricular Node; D017115:Catheter Ablation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011875:Radionuclide Angiography; D013318:Stroke Volume; D016277:Ventricular Function, Left