[POEMS syndrome: role and value of interleukin-6].
POEMS syndrome is a systemic disorder with peripheral neuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes. The association of POEMS syndrome with lympho-proliferative disorder is very commun. The pathogenesis remains poorly understood but implication of cytokines (interleukins 1 and 6) is suspected. We report a case of a classic POEMS syndrome (with polyneuropathy, hepatomegaly, diabetes melitus, hyperpigmentation, monoclonal IgG lambda, anasarca and solitary plasmocytoma), associated with high serum levels of interleukin 6.
Andrès
E
E
Service de médecine interne, CHU de Strasbourg, hôpital de Hautepierre, France.
Courouau
F
F
Kaltenbach
G
G
Maloisel
F
F
Imler
M
M
D006801:Humans; D015850:Interleukin-6 / Q000097:blood / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D016878:POEMS Syndrome / Q000097:blood / Q000175:diagnosis / Q000503:physiopathology*; D011379:Prognosis
D015850:Interleukin-6
Syndrome POEMS: rôles et intérêts de l'interleukine 6.