Upper airway compromise in acute chlorpromazine ingestion.
A 16-year-old boy developed symptoms of acute upper airway compromise after chlorpromazine ingestion. The patient took six 100-mg Thorazine tablets "to help him sleep". Laryngeal-pharyngeal dystonia is a life-threatening form of dystonic reaction that is dose-dependent. In children, acute upper airway compromise should raise the suspicion of exposure to phenothiazines.
Russell
S A
SA
Medical College of Wisconsin, Milwaukee, USA.
Hennes
H M
HM
Herson
K J
KJ
Stremski
E S
ES
D000293:Adolescent; D000402:Airway Obstruction / Q000139:chemically induced*; D014150:Antipsychotic Agents / Q000506:poisoning*; D002746:Chlorpromazine / Q000506:poisoning*; D003680:Deglutition Disorders / Q000139:chemically induced; D062787:Drug Overdose; D006801:Humans; D008260:Macroglossia / Q000139:chemically induced; D008297:Male
D014150:Antipsychotic Agents; D002746:Chlorpromazine