title: Vascular infections: exceeding the threshold.
abstract: During fiscal year 1988, our hospital infection control practitioner identified a 400% increase in the incidence of vascular surgery nosocomial infections. The six graft and six amputation infections were validated as nosocomial against hospital definitions adopted from the Centers for Disease Control. Our Infection Control Committee mandated an audit of the infected vascular surgery patients using a case/control design to identify and examine associated variables that may need attention. The significant finding was microbial resistance to prophylactic antibiotics used during surgery (p > 0.0001, Fisher's exact). The use of vancomycin as a prophylactic antimicrobial agent for all major vascular cases was recommended to the surgeons.
authors.affiliation: Harry S. Truman Memorial VA Hospital, Columbia, MO 65201, USA.
authors.forename: T R
authors.initials: TR
authors.lastname: Cox
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D003428:Cross Infection / Q000453:epidemiology; D004352:Drug Resistance, Microbial; D006801:Humans; D012189:Retrospective Studies; D013530:Surgical Wound Infection / Q000188:drug therapy* / Q000453:epidemiology; D014640:Vancomycin / Q000627:therapeutic use*; D014656:Vascular Surgical Procedures
chemical_list: D000900:Anti-Bacterial Agents; D014640:Vancomycin