title: Trichilemmal carcinoma developing in a burn scar: a report of two cases.
abstract: Two cases of trichilemmal carcinoma (TLC) developing in burn scars are reported. In Case 1, a 73-year-old man developed a TLC on his left lower leg five years after a burn. In Case 2, a 43-year-old man developed a cauliflower-like mass on his head 42 years after a burn. Histologically, tumor cells showed a lobular proliferation in continuity with the epidermis. Tumor nests were mostly composed of large atypical cells with clear cytoplasms containing PAS-positive, diastase sensitive materials. Some of the nests showed trichilemmal-type keratinization. These cases were treated only with surgical excision, and there has been no evidence since of local recurrence or metastasis.
authors.affiliation: Department of Dermatology, Nara Medical University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ko
authors.forename: H
authors.initials: H
authors.lastname: Tada
authors.forename: M
authors.initials: M
authors.lastname: Hatoko
authors.forename: T
authors.initials: T
authors.lastname: Muramatsu
authors.forename: T
authors.initials: T
authors.lastname: Shirai
mesh_terms: D000328:Adult; D000368:Aged; D002056:Burns / Q000473:pathology*; D002921:Cicatrix / Q000473:pathology*; D003593:Cytoplasm / Q000648:ultrastructure; D004817:Epidermis / Q000293:injuries; D006801:Humans; D007633:Keratins; D007869:Leg Injuries / Q000473:pathology; D008297:Male; D018295:Neoplasms, Basal Cell / Q000473:pathology*; D012535:Scalp / Q000293:injuries; D012878:Skin Neoplasms / Q000473:pathology*
chemical_list: D007633:Keratins