title: [Neonatal cholestatic lithiasis associated with E. coli infection].
abstract: BACKGROUND
  Cholestasis associated with gallbladder lithiasis is quite uncommon in the neonate. We report such a case possibly due to a bacterial infection.
  
  
  METHODS
  A 25 day-old neonate was admitted because he suffered from cholestatic jaundice associated with biological findings of inflammation. Hepatic cellular function and transaminases were normal. Ultrasonography showed hepatomegaly and a 10 mm diameter gallstone with sludge into the gallbladder. The patient was given cefotaxime plus netilmicine. Soluble antigenes for E coli were positive in the urine. Jaundice and inflammatory findings returned to normal within 10 days and ultrasonography was normal at the age of 20 months.
  
  
  CONCLUSIONS
  Neonatal E coli infection could be responsible for gallstone formation since E coli endotoxin may induce biliary stasis and favours lithogenous action of bacterial glycoproteins.
authors.affiliation: Service de pédiatrie, centre hospitalier, Fontainebleau, France.
authors.forename: K
authors.initials: K
authors.lastname: Alissa
authors.forename: P
authors.initials: P
authors.lastname: Saunier
authors.forename: M
authors.initials: M
authors.lastname: Russo
authors.forename: J
authors.initials: J
authors.lastname: Vedrenne
mesh_terms: D002769:Cholelithiasis / Q000150:complications* / Q000000981:diagnostic imaging; D002779:Cholestasis / Q000150:complications*; D004927:Escherichia coli Infections / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D014463:Ultrasonography
vernacular_title: Lithiase cholestatique néonatale associée à une infection à colibacilles.