title: Co-metabolism: is the emperor wearing any clothes?
abstract: Co-metabolism is a term used for biochemically undefined observations in catabolic enzyme substrate specificity, the interplay between enzyme specificity and metabolic regulation, the metabolic interdependence of microorganisms, and co-substrate requirements in the catabolism of xenobiotic compounds. Recent findings in these four areas of microbial biochemistry necessitate a re-evaluation of the widespread use of the term.
authors.affiliation: Department of Biochemistry, University of Minnesota, St Paul 55108, USA. wackett@biosci.cbs.umn.edu
authors.forename: L P
authors.initials: LP
authors.lastname: Wackett
mesh_terms: D001419:Bacteria / Q000201:enzymology / Q000235:genetics; D001673:Biodegradation, Environmental; D001709:Biotechnology; D004798:Enzymes / Q000235:genetics / Q000378:metabolism*; D015971:Gene Expression Regulation, Enzymologic; D013379:Substrate Specificity; D015262:Xenobiotics / Q000378:metabolism
chemical_list: D004798:Enzymes; D015262:Xenobiotics