title: [Changes in platelet activity in invasive cardiologic procedures].
abstract: The authors revealed some changes in the platelet activity in patients with invasive cardiological procedures. Changes of the platelet function were manifested by an enhanced aggregation of platelets in vivo, an increased secretion from alpha granules and increased release of prostaglandin metabolites from platelets and from the vascular wall. Acetylsalicylic acid (ASA) suppressed the formation of circulating platelet aggregates in vivo, but the platelet activity was manifested by another mechanism, independent on ASA. The authors recorded therefore an increase of prostaglandin metabolites and PF4 even in patients who were treated with ASA before the invasive examination.
authors.affiliation: 2, katedra vnitrních oborů LF UK, Hradec Králové.
authors.forename: J
authors.initials: J
authors.lastname: Malý
authors.forename: M
authors.initials: M
authors.lastname: Pecka
authors.forename: M
authors.initials: M
authors.lastname: Pleskot
authors.forename: D
authors.initials: D
authors.lastname: Cernohorský
authors.forename: V
authors.initials: V
authors.lastname: Pidrman
authors.forename: J
authors.initials: J
authors.lastname: Stásek
authors.forename: M
authors.initials: M
authors.lastname: Bláha
authors.forename: O
authors.initials: O
authors.lastname: Siroký
authors.forename: L
authors.initials: L
authors.lastname: Jebavý
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D001241:Aspirin / Q000494:pharmacology; D002304:Cardiac Pacing, Artificial; D017023:Coronary Angiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015539:Platelet Activation / Q000187:drug effects
chemical_list: D001241:Aspirin
vernacular_title: Zmĕny aktivity desticek pri invazivních kardiologických výkonech.