title: Biocompatibility of polysulfone I. Surface modifications and characterizations.
abstract: Surface treatments by nonionic surfactant (Brij) coating and air-plasma glow discharge treatment onto polysulfone have been investigated to improve its surface properties. Surface treated samples were characterized by measurement of contact angle by a goniometer, Fourier transform infrared spectroscopy in the attenuated total reflectance mode (FTIR-ATR), and electron spectroscopy for chemical analysis (ESCA). The contact angles of the nonionic surfactant coated films decreased from 66.6 +/- 2.1 degrees to nearly 0 degrees due to hydrophilic polyethylene oxide (PEO) chain segment of the nonionic surfactant, and those of air-plasma treated films also decreased from 66.6 degrees to about 22 degrees with a treatment time of less than 5 s. ESCA analysis of air-plasma treated films indicates the incorporation of oxygen molecules onto polysulfone surface lowers the water contact angle. These modified techniques can be used to prevent platelet adhesion onto polysulfone surfaces.
authors.affiliation: Department of Biomedical Engineering, University of Iowa, Iowa City 52242, USA.
authors.forename: G
authors.initials: G
authors.lastname: Khang
authors.forename: H B
authors.initials: HB
authors.lastname: Lee
authors.forename: J B
authors.initials: JB
authors.lastname: Park
mesh_terms: D000327:Adsorption; D001672:Biocompatible Materials / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D010100:Oxygen / Q000737:chemistry; D010973:Platelet Adhesiveness; D011092:Polyethylene Glycols / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods; D013057:Spectrum Analysis; D013450:Sulfones / Q000737:chemistry*; D013455:Sulfur / Q000737:chemistry; D013499:Surface Properties; D013501:Surface-Active Agents / Q000737:chemistry; D017155:Wettability
chemical_list: D001672:Biocompatible Materials; D011108:Polymers; D013450:Sulfones; D013501:Surface-Active Agents; C017662:polysulfone P 1700; D011092:Polyethylene Glycols; D013455:Sulfur; D002244:Carbon; D010100:Oxygen