[Significance of organ donor characteristics in renal function at 1 month: reflection on the allocation of renal transplant].
In a series of 731 kidneys taken from brain-dead donors for renal transplantation, 652 were grafted, and the renal function at 1 month is known for 490 of them. The results show that some donor-related factors influence the outcome of the transplant. In particular, haemodynamic instability refractory to medical treatment is responsible for a 50 mumol increase of serum creatinine one month after transplantation and the use of UW solution during organ collection is responsible for an improvement of serum creatinine compared to other preservation solutions. Haemodynamic instability is a criterion which must be added to those already demonstrated in donors, such as the cause of death, age and sex. The authors propose that donor-related factors be taken into account in the allocation of organs in the same way as immunological factors which, at the present time, constitute the only criterion for kidney allocation.
Benoit
G
G
Service d'Urologie, CHU de Bicêtre, Le Kremlin Bicêtre.
Blanchet
P
P
Decaux
A
A
Decaris
J
J
Joseph
L
L
Charpentier
B
B
Samii
K
K
Huault
G
G
Auzepy
P
P
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D016030:Kidney Transplantation / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014019:Tissue Donors; D009927:Tissue and Organ Procurement
Importance des caractéristiques des donneurs d'organes sur le devenir de la fonction rénale à 1 mois: réflexion sur la répartition des greffons rénaux.