title: Gastric intramucosal pH and hepatic venous oximetry after cardiopulmonary bypass in valve replacement patients.
abstract: To determine splanchnic perfusion after cardiopulmonary bypass, gastric intramucosal pH (pH(i)) and hepatic venous oxygen saturation (SHVO2) were measured in 14 patients with cardiac valve replacement. Blood samples were analysed at 6, 12 and 24 h after admission to an intensive care unit. Gastric pH(i) increased significantly (P < 0.01) from 7.21 at 6 h to 7.31 at 12h and increased to 7.37 at 24 h while SHVO2 increased significantly (P < 0.05) from 48% at 6 h to 57% at 12 h and 24 h. Cardiac index was > 4 l/min per m2 and mixed venous oxygen saturation > 70%. Despite sufficient cardiac output, splanchnic perfusion decreased after cardiopulmonary bypass and recovered within 24 h after admission to the intensive care unit. It is concluded that gastric pH(i) and SHVO2 are useful parameters for monitoring postoperative splanchnic perfusion in patients with open-heart surgery.
authors.affiliation: Second Department of Surgery, Gunma University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Takahashi
authors.forename: F
authors.initials: F
authors.lastname: Kunimoto
authors.forename: H
authors.initials: H
authors.lastname: Ichikawa
authors.forename: S
authors.initials: S
authors.lastname: Ishikawa
authors.forename: Y
authors.initials: Y
authors.lastname: Sato
authors.forename: Y
authors.initials: Y
authors.lastname: Hasegawa
authors.forename: Y
authors.initials: Y
authors.lastname: Morishita
mesh_terms: D000136:Acid-Base Equilibrium / Q000502:physiology*; D001021:Aortic Valve / Q000503:physiopathology / Q000601:surgery; D002315:Cardiopulmonary Bypass; D003422:Critical Care; D005745:Gastric Acidity Determination; D005753:Gastric Mucosa / Q000503:physiopathology*; D006349:Heart Valve Diseases / Q000503:physiopathology / Q000601:surgery*; D006350:Heart Valve Prosthesis; D006503:Hepatic Veins; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D008943:Mitral Valve / Q000503:physiopathology / Q000601:surgery; D010100:Oxygen / Q000097:blood*; D011183:Postoperative Complications / Q000503:physiopathology*; D013152:Splanchnic Circulation / Q000502:physiology
chemical_list: D010100:Oxygen