Metabolic aspects of acromegaly and its treatment.
Growth hormone (GH) affects virtually all facets of metabolism. This review concentrates on the effects of GH excess on carbohydrate, lipid, and bone metabolism, and on body composition. The effect of treatment with the somatostatin analog, octreotide, on the gastrointestinal-pancreatic axis is also discussed.
Quabbe
H J
HJ
Department of Endocrinology, Klinikum Benjamin Franklin, Berlin, Germany.
Plöckinger
U
U
D000172:Acromegaly / Q000188:drug therapy* / Q000378:metabolism*; D001823:Body Composition / Q000187:drug effects; D001842:Bone and Bones / Q000378:metabolism; D050260:Carbohydrate Metabolism; D013006:Growth Hormone / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D015282:Octreotide / Q000627:therapeutic use*
D013006:Growth Hormone; D015282:Octreotide