Statistical properties of the allelic and genotypic transmission/disequilibrium test for multiallelic markers.
The transmission/disequilibrium test (TDT) is extended in two ways for a multiallelic marker: (1) to compare transmitted and nontransmitted alleles from a single heterozygous parent and (2) to compare genotypes formed by the two transmitted alleles and genotypes formed by the two nontransmitted alleles using the information on both parents, heterozygous or not, simultaneously.
Bickeböller
H
H
INSERM Unité 155, Paris, France.
Clerget-Darpoux
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F
D000483:Alleles; D005260:Female; D005787:Gene Frequency; D030342:Genetic Diseases, Inborn / Q000235:genetics*; D005819:Genetic Markers; D005838:Genotype; D006579:Heterozygote; D006801:Humans; D015810:Linkage Disequilibrium; D008297:Male; D008957:Models, Genetic; D015233:Models, Statistical; D009679:Nuclear Family
D005819:Genetic Markers