title: Modulation of microtubule dynamics during the cell cycle.
abstract: Microtubule dynamics change dramatically during the cell cycle, but the mechanisms by which these changes occur are unknown. Recent progress has been made in four areas: firstly, in the determination of changes in microtubule turnover and net tubulin polymer levels in vivo; secondly, in the elucidation of mechanisms of regulation of microtubule dynamics by microtubule-associated protein 4; thirdly, in the determination of the mechanisms by which Xenopus microtubule-associated protein regulates microtubule dynamics; and fourthly, in the elucidation of the structural basis of microtubule nucleation by gamma tubulin.
authors.affiliation: Section of Molecular and Cellular Biology, University of California, Davis 95616, USA. fjmcnally@ucdavis.edu
authors.forename: F J
authors.initials: FJ
authors.lastname: McNally
mesh_terms: D002453:Cell Cycle / Q000502:physiology*; D008870:Microtubules / Q000378:metabolism*