title: [Kinetics of sialylation of Neisseria gonorrhoeae by radiolabelled cytidine 5'monophospho-N-acetyl neuraminic acid].
abstract: Neisseria gonorrhoeae (Strain A) induces a sialyl-transferase when treated with a very low concentration of cytidine 5'monophospho-N-acetyl neuraminic acid, 2 x 10(-3) nmol.ml-1, a concentration which is insufficient to produce an adequate resistance to human serum complement. The sialyl-transferase activity was detected by measurement of fixed 14C radio-labeled sialyl groups. Without this stimulation, there was practically no transfer of sialyl groups. The gonococcal sialyl-transferase could be considered inducible.
authors.affiliation: Département de Microbiologie, Université Laval, SAINTE-FOY, Québec, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Goldner
authors.forename: J P
authors.initials: JP
authors.lastname: Emond
authors.forename: E
authors.initials: E
authors.lastname: Germani
authors.forename: J M
authors.initials: JM
authors.lastname: Launay
authors.forename: A
authors.initials: A
authors.lastname: Dublanchet
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002250:Carbon Radioisotopes; D002701:Chloramphenicol / Q000494:pharmacology; D003569:Cytidine Monophosphate N-Acetylneuraminic Acid / Q000494:pharmacology*; D066298:In Vitro Techniques; D009344:Neisseria gonorrhoeae / Q000187:drug effects* / Q000378:metabolism; D011874:Radiometry; D012799:Sialyltransferases / Q000493:pharmacokinetics*; D013268:Stimulation, Chemical
chemical_list: D000900:Anti-Bacterial Agents; D002250:Carbon Radioisotopes; D003569:Cytidine Monophosphate N-Acetylneuraminic Acid; D002701:Chloramphenicol; D012799:Sialyltransferases
vernacular_title: Cinétique de sialylation de Neisseria gonorrhoeae par l'acide cytidine 5'monophospho-n-acétyl neuraminique radio-marqué.