A new hypothesis for faster healing of fractures in head injured patients.
A new hypothesis has been proposed to explain excessive callus formation seen after injury to brain or spinal cord. Nervous tissue is very active metabolically and when damaged or inflammed it extracts, utilises and inactivates most of the corticosteroids and other anti-inflammatory substances present in the blood. Therefore now very little active corticosteroids are left to exhibit the inhibitory effect on callus formation. This leads to faster fracture healing with excessive callus formation in head or spinal cord injured patients.
Khare
G N
GN
Department of Orthopaedics Institute of Medical Sciences Banaras Hindu University Varanasi.
Gautam
V K
VK
Gupta
L N
LN
Gupta
A K
AK
D000293:Adolescent; D000328:Adult; D000368:Aged; D002146:Bony Callus / Q000502:physiology; D001930:Brain Injuries / Q000150:complications / Q000503:physiopathology*; D002648:Child; D005260:Female; D005264:Femoral Fractures / Q000150:complications; D017102:Fracture Healing / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged