title: Comparison of i.v. and s.c. diamorphine infusions for the treatment of acute pain in children.
abstract: We have compared the i.v. and s.c. routes of administration for diamorphine infusions in children undergoing abdominal surgery. Subjects received general anaesthesia with extradural block and diamorphine up to 20 micrograms kg-1 h-1 after operation. There were no differences between the groups in diamorphine consumption, pain scores or incidence of side effects. The s.c. route appeared to be as effective and safe as the i.v. route for administration of diamorphine infusions in children undergoing elective surgery.
authors.affiliation: Department of Anaesthesia, Royal Hospital for Sick Children, Edinburgh.
authors.forename: D
authors.initials: D
authors.lastname: Semple
authors.forename: L A
authors.initials: LA
authors.lastname: Aldridge
authors.forename: E
authors.initials: E
authors.lastname: Doyle
mesh_terms: D000005:Abdomen / Q000601:surgery*; D000208:Acute Disease; D000698:Analgesia / Q000379:methods; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000627:therapeutic use; D000768:Anesthesia, General; D002648:Child; D002675:Child, Preschool; D003932:Heroin / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007262:Infusions, Intravenous; D007263:Infusions, Parenteral; D010149:Postoperative Pain / Q000188:drug therapy*
chemical_list: D000701:Analgesics, Opioid; D003932:Heroin