title: Choroid plexus size in young children with Sturge-Weber syndrome.
abstract: OBJECTIVE
  To assess the size of the choroid plexus in young children with unilateral and bilateral Sturge-Weber syndrome.
  
  
  METHODS
  Subjects included 15 children 4 years old or younger with Sturge-Weber syndrome. Eleven cases were unilateral and four were bilateral. Unilateral or bilateral involvement was determined by the distribution of abnormal leptomeningeal enhancement on MR images. The diameters of the choroid plexus were measured on contrast-enhanced axial MR images. The choroid plexus of the affected and unaffected sides in these cases were compared with those of 15 age-matched children without Sturge-Weber syndrome who were being examined for seizures.
  
  
  RESULTS
  Our results show a wide variation in the size of the choroid plexus in children with Sturge-Weber syndrome; however, plexus associated with a hemisphere affected by Sturge-Weber syndrome were significantly larger than those on the unaffected side and in the age-matched control group. The size of the choroid plexus was positively correlated with the extent of leptomeningeal involvement as demonstrated by abnormal contrast enhancement.
  
  
  CONCLUSIONS
  The choroid plexus is enlarged early in the course of Sturge-Weber syndrome in both unilateral and bilateral cases. There is a positive correlation between choroid plexus size and extent of leptomeningeal involvement in children with Sturge-Weber syndrome.
authors.affiliation: Department of Neuroradiology, Newcastle General Hospital, Newcastle upon Tyne, United Kingdom.
authors.forename: P D
authors.initials: PD
authors.lastname: Griffiths
authors.forename: S
authors.initials: S
authors.lastname: Blaser
authors.forename: M B
authors.initials: MB
authors.lastname: Boodram
authors.forename: D
authors.initials: D
authors.lastname: Armstrong
authors.forename: D
authors.initials: D
authors.lastname: Harwood-Nash
mesh_terms: D002675:Child, Preschool; D002831:Choroid Plexus / Q000473:pathology*; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008578:Meninges / Q000473:pathology; D009460:Neurologic Examination; D013341:Sturge-Weber Syndrome / Q000175:diagnosis*