title: A novel device for patient-controlled sedation: laboratory and clinical evaluation of the Baxter Intermate LV250 infusor and patient-control module.
abstract: The Baxter Intermate LV250 infusor is a large capacity, high flow mechanical infusor, designed to deliver viscous solutions and suspensions. The objective of the laboratory study was to evaluate the LV250 infusor when used with either 0.9% sodium chloride solution or an emulsion, propofol 1%. Following this, the LV250 infusor with the patient-control module was assessed in the clinical setting as to its suitability for use in patient-controlled sedation with a propofol and lignocaine mixture. Between reservoir volumes of 250 and 55 ml, the LV250 infusor was found to infuse a propofol 1% and lignocaine mixture at a lower flow compared with the sodium chloride solution, 170 ml.h-1 and 260 ml.h-1 respectively. The lower flow with the propofol mixture may be a result of its higher viscosity. All patients using the LV250 infusor for patient-controlled sedation found it easy to use and stated that they were able to achieve their desired level of sedation. All patients maintained arterial oxygen saturations above 95%. The LV250 infusor performed reliably and with little inter-device variation, and with the patient-control module could be used as an alternative to electronic devices for providing patient-controlled sedation. Compared with electronic infusors, its advantages include compactness and simplicity of design.
authors.affiliation: University Department of Anaesthesia, Western Infirmary, Glasgow.
authors.forename: S K
authors.initials: SK
authors.lastname: Hamid
authors.forename: P K
authors.initials: PK
authors.lastname: Wong
authors.forename: F
authors.initials: F
authors.lastname: Carmichael
authors.forename: K
authors.initials: K
authors.lastname: White
authors.forename: A J
authors.initials: AJ
authors.lastname: Asbury
mesh_terms: D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D000779:Anesthetics, Local / Q000008:administration & dosage; D016292:Procedural Sedation / Q000295:instrumentation*; D003814:Dentistry, Operative; D004334:Drug Administration Schedule; D005069:Evaluation Studies as Topic; D006801:Humans; D007260:Infusion Pumps; D008012:Lidocaine / Q000008:administration & dosage; D015742:Propofol / Q000008:administration & dosage*; D012646:Self Administration
chemical_list: D018686:Anesthetics, Intravenous; D000779:Anesthetics, Local; D008012:Lidocaine; D015742:Propofol