title: Three-phase bone scan pattern in asymptomatic uncemented total knee arthroplasty.
abstract: In this study we investigated the bone scan pattern in a homogeneous group of asymptomatic patients implanted with the same type of total knee arthroplasty (TKA) and with a minimum follow-up of 2 years. Twenty-nine patients (21 females, 8 males, mean age 62 years), with a total of 30 uncemented Hofmann TKAs, were entered in the study. The time interval from surgery to scintigraphic evaluation ranged from 2 to 4 years. Bone scan was performed using the three-phase technique and images were interpreted by visual analysis using a three-point scale for the dynamic and blood pool phases and a five-point scale for the bone phase. Areas of increased periprosthetic technetium-99m methylene diphosphonate (MDP) uptake were observed until 4 years after surgery. However, comparing the TKAs implanted 2, 3 and 4 years previously, a decreasing pattern in tracer uptake intensity was noted this being more evident in the femoral and lateral tibial components. In some cases, a persistently elevated tracer uptake, not exceeding a moderate grade, was found in the medial tibial component. In conclusion, increased periprosthetic 99mTc-MDP uptake is a common finding in asymptomatic uncemented Hofmann TKAs for a prolonged period after surgery, but the uptake intensity is generally mild or moderate and shows a characteristic decreasing pattern over time. Furthermore, in contrast with other types of asymptomatic knee implants previously investigated, no case of high or very high bone uptake was recorded with this type of implant. We may speculate that scintigraphic parameters of normality, and pathology, should be determined for each type of TKA. It is likely that, with the uncemented Hofmann TKA, a high or very high tracer uptake or a progressive increase in the uptake intensity is suggestive of the presence of complications.
authors.affiliation: Nuclear Medicine-PET Center, General Hospital of Castelfranco Veneto (TV), Italy.
authors.forename: D
authors.initials: D
authors.lastname: Rubello
authors.forename: D
authors.initials: D
authors.lastname: Caricasulo
authors.forename: N
authors.initials: N
authors.lastname: Borsato
authors.forename: F
authors.initials: F
authors.lastname: Chierichetti
authors.forename: P
authors.initials: P
authors.lastname: Zanco
authors.forename: G
authors.initials: G
authors.lastname: Ferlin
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007717:Knee / Q000000981:diagnostic imaging*; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate; D013997:Time Factors
chemical_list: D013669:Technetium Tc 99m Medronate