[Pharmacodynamic changes in the elderly subject].
Age-related physiological changes alter drug responsiveness in the elderly. The changes of pharmacokinetics are widely known but they do not explain completely the altered drug action in the elderly. In this work the authors deal with the alterations of pharmacodynamics which could be responsible for the different pharmacological action and the high frequency of side effects which can be found in old age.
Beltrami
G
G
I Divisione Medica Geriatrica, Azienda Ospedaliera di Verona.
Menegolli
G
G
Bellamoli
C
C
Grezzana
L
L
Zavateri
G
G
D000368:Aged; D000375:Aging / Q000187:drug effects* / Q000378:metabolism; D006706:Homeostasis / Q000187:drug effects; D006801:Humans; D010599:Pharmacokinetics; D011955:Receptors, Drug / Q000187:drug effects / Q000378:metabolism
D011955:Receptors, Drug
Modificazioni della farmacodinamica nel soggetto anziano.