title: Ocular torsion monitoring in chemical labyrinthectomy.
abstract: OBJECTIVE
  To study the usefulness of ocular torsion analysis as an adjunct to examining central vestibular compensation.
  
  
  METHODS
  Prospective evaluation.
  
  
  METHODS
  The Vestibular Disorders Clinic, University of Manitoba Health Sciences Centre.
  
  
  METHODS
  Seven patients with intractable Meniere's disease underwent elective transtympanic gentamycin labyrinthectomy. Serial examination of patient progress was performed using fundus photography, subjective visual vertical estimations, electronystagmography, and audiometry.
  
  
  RESULTS
  Ocular torsion analysis reveals unexpected initial and early contraversive torsion behaviour in some patients, which may represent an early irritative phenomenon stemming from either the gentamicin or the Meniere's disease itself.
  
  
  CONCLUSIONS
  Despite the sensitivity of the ocular torsion measures, there appears to be no useful predictive correlation between ocular torsion and audiometric functioning that might predict impending hearing loss. Nevertheless, ocular torsion analysis reveals subtle changes in vestibular system functioning and may provide useful adjunctive information in the assessment of vestibular ototoxicity.
authors.affiliation: Department of Otolaryngology, University of Manitoba Faculty of Medicine and Health Sciences Centre, Winnipeg.
authors.forename: D D
authors.initials: DD
authors.lastname: Robertson
authors.forename: L Z
authors.initials: LZ
authors.lastname: Garber
authors.forename: D J
authors.initials: DJ
authors.lastname: Ireland
mesh_terms: D000328:Adult; D000368:Aged; D001301:Audiometry, Pure-Tone; D004584:Electronystagmography; D005584:Fovea Centralis / Q000187:drug effects; D005839:Gentamicins / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D006311:Hearing Disorders / Q000175:diagnosis; D006801:Humans; D008575:Meniere Disease / Q000150:complications / Q000188:drug therapy; D008875:Middle Aged; D009900:Optic Nerve / Q000187:drug effects / Q000503:physiopathology*; D011446:Prospective Studies; D013063:Speech Discrimination Tests; D014102:Torsion Abnormality / Q000209:etiology / Q000503:physiopathology
chemical_list: D005839:Gentamicins