[The use of phenylthiocarbamide for evaluating the degree of cAMP-dependent resistance to hypoxia in animals].
Responses to a 5-min anoxia were studied in cats with different taste sensitivity for phenilthiocarbamide (PTC). The sensitive animals were more resistant against hypoxia. The difference in the cats seems to be determined by the condition of the cAMP system involved in adaptive responses.
Bolekhan
E A
EA
Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg.
Semenov
D G
DG
Gerasimova
I A
IA
Samoĭlov
M O
MO
D000222:Adaptation, Physiological / Q000187:drug effects; D000818:Animals; D001923:Brain Chemistry / Q000187:drug effects; D002415:Cats; D000242:Cyclic AMP / Q000032:analysis / Q000235:genetics / Q000502:physiology*; D004195:Disease Models, Animal; D000860:Hypoxia / Q000235:genetics / Q000503:physiopathology*; D009044:Motor Cortex / Q000737:chemistry / Q000187:drug effects / Q000502:physiology; D010670:Phenylthiourea / Q000494:pharmacology*; D013649:Taste / Q000187:drug effects; D013997:Time Factors
D010670:Phenylthiourea; D000242:Cyclic AMP
Ispol'zovanie feniltiokarbamida dlia otsenki stepeni tsAMF-zavisimoĭ rezistentnosti zhivotnykh k gipoksii.