Kaposi's disease and sarcoidosis.
A human immunodeficiency virus (HIV) antibody-negative 65 year old woman was treated with corticosteroids for 7 yrs because of bilateral uveitis. One year after the beginning of corticosteroid treatment, erythematous skin lesions appeared on the legs. Eight years after the diagnosis of uveitis, gastric and bronchial biopsies revealed noncaseating epithelioid cell granulomas, whilst a cutaneous biopsy showed Kaposi's disease. Sarcoidosis-associated alteration of immune regulation and corticosteroid therapy may have promoted the development of disease.
Corda
L
L
Terza Divisione di Medicina Generale, Spedali Civili, Brescia, Italy.
Benerecetti
D
D
Ungari
M
M
Facchetti
F
F
Radaeli
E
E
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000368:Aged; D017809:Fatal Outcome; D005260:Female; D018023:HIV Seronegativity; D006801:Humans; D008168:Lung / Q000473:pathology; D017565:Sarcoidosis, Pulmonary / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D014605:Uveitis / Q000150:complications / Q000188:drug therapy; D014983:Xeroderma Pigmentosum / Q000150:complications* / Q000175:diagnosis / Q000628:therapy
D000305:Adrenal Cortex Hormones