title: [Gastric adenocarcinomas (excluding linites). Prognostic factors apropos of a series of 101 cases].
abstract: The incidence of some factors on prognosis of adenocarcinoma of the stomach was evaluated in 101 cases. Linites as well as cancers of the cardia were excluded from the analysis. There were 47 total gastrectomies with more or less extensive node dissection and 54 partial gastrectomies. Overall actuarial survival was 34.5% despite the large number of advanced stage cancers (70% positive lymph nodes, 35 with invasion of neighbouring organs, 13 cases of carcinosis and 13 with liver metastasis). Univariate analysis showed that the following factors were associated with poor prognosis: invasion of the serous layer, nodal involvement, emboli, degree of differentiation. Peritumoural reactional lymphoid infiltration, the presence of a chronic gastritis and intestinal metaplasia were found to be favourable factors. Gastric resection appeared to have less impact than the quality of the nodal dissection. These findings emphasize the importance of extensive dissection of the lymph nodes (survival ranging from 31 to 78% depending on the node score). Extensive dissection, allowing better locoregional control of the disease, improved prognosis whatever the size of the tumour (14.8% survival in case extending to neighbouring organs). The only exceptions were palliative exereses and N4+ cases.
authors.affiliation: Clinique Chirurgicale I, CHR, Nantes.
authors.forename: J
authors.initials: J
authors.lastname: Visset
authors.forename: S
authors.initials: S
authors.lastname: Bouvier
authors.forename: J M
authors.initials: JM
authors.lastname: N'Guyen
authors.forename: M
authors.initials: M
authors.lastname: Fiche
authors.forename: J
authors.initials: J
authors.lastname: Paineau
authors.forename: B
authors.initials: B
authors.lastname: Savigny
authors.forename: A
authors.initials: A
authors.lastname: Hamy
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005743:Gastrectomy / Q000401:mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*
vernacular_title: Adénocarcinomes gastriques (linites exclues). Facteurs pronostiques à propos d'une série de 101 cas.