title: Disturbances of thyroid function tests by drugs.
abstract: Commonly prescribed drugs can variously cause changes in measuring serum T3 and T4 concentrations. Thus spuriously normal thyroid hormone levels may result in moderate hypo- or hyperthyroidism, or the influence of pharmacological substances may lead to a false diagnosis of thyroid disease in euthyroid subjects. On the other hand numerous pharmacological agents, especially those interacting with neurotransmitters, may influence TSH secretion, too. While generally such drug-induced abnormal thyroid tests do not correspond to clinical features of thyroid dysfunction, iodine containing drugs, especially amiodarone, may result in overt thyroid disease.
authors.affiliation: Rudolf Virchow University Hospital, Department of Medicine, Free University of Berlin, Germany.
authors.forename: K W
authors.initials: KW
authors.lastname: Wenzel
mesh_terms: D000638:Amiodarone / Q000009:adverse effects; D003937:Diagnosis, Differential; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D011237:Predictive Value of Tests; D013959:Thyroid Diseases / Q000097:blood / Q000139:chemically induced / Q000175:diagnosis; D013960:Thyroid Function Tests; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
chemical_list: D014284:Triiodothyronine; D013972:Thyrotropin; D000638:Amiodarone; D013974:Thyroxine