title: Radiotherapy for stage I and II testicular seminoma after orchidectomy.
abstract: A retrospective study was undertaken to evaluate the effect of irradiation on 65 patients with stage I, or II testicular seminomas treated at Hillbrow Hospital with irradiation following orchidectomy. Forty-seven patients presented with stage 1 and 9 with stage II disease. All patients received infradiaphragmatic irradiation. In addition 4 patients with stage II disease received prophylactic supradiaphragmatic irradiation. The 5-year overall and disease-free survival rate for all stages and for stage I and II compared favourably with other reports in the literature. The irradiation was well tolerated and severe long-term toxicity was rare. Seminomas were uncommon in black patients, of whom only 3 were seen in the 12-year period of this study.
authors.affiliation: Department of Radiation Oncology, University of the Witwatersrand, Johannesburg.
authors.forename: S
authors.initials: S
authors.lastname: Malas
authors.forename: R K
authors.initials: RK
authors.lastname: Sur
authors.forename: J A
authors.initials: JA
authors.lastname: Pacella
authors.forename: B
authors.initials: B
authors.lastname: Donde
authors.forename: R
authors.initials: R
authors.lastname: Uijs
authors.forename: C V
authors.initials: CV
authors.lastname: Levin
mesh_terms: D000328:Adult; D000368:Aged; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D009919:Orchiectomy; D011878:Radiotherapy / Q000009:adverse effects; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D018239:Seminoma / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D015996:Survival Rate; D013736:Testicular Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery