Trichilemmal carcinoma developing in a burn scar: a report of two cases.
Two cases of trichilemmal carcinoma (TLC) developing in burn scars are reported. In Case 1, a 73-year-old man developed a TLC on his left lower leg five years after a burn. In Case 2, a 43-year-old man developed a cauliflower-like mass on his head 42 years after a burn. Histologically, tumor cells showed a lobular proliferation in continuity with the epidermis. Tumor nests were mostly composed of large atypical cells with clear cytoplasms containing PAS-positive, diastase sensitive materials. Some of the nests showed trichilemmal-type keratinization. These cases were treated only with surgical excision, and there has been no evidence since of local recurrence or metastasis.
Ko
T
T
Department of Dermatology, Nara Medical University, Japan.
Tada
H
H
Hatoko
M
M
Muramatsu
T
T
Shirai
T
T
D000328:Adult; D000368:Aged; D002056:Burns / Q000473:pathology*; D002921:Cicatrix / Q000473:pathology*; D003593:Cytoplasm / Q000648:ultrastructure; D004817:Epidermis / Q000293:injuries; D006801:Humans; D007633:Keratins; D007869:Leg Injuries / Q000473:pathology; D008297:Male; D018295:Neoplasms, Basal Cell / Q000473:pathology*; D012535:Scalp / Q000293:injuries; D012878:Skin Neoplasms / Q000473:pathology*
D007633:Keratins