title: [Primary signet ring cell adenocarcinoma of the bladder. Report of 2 cases of bladder plastic linitis].
abstract: OBJECTIVE
  Two additional cases of signet-ring cell adenocarcinoma of the urinary bladder, an uncommon highly malignant tumor type, are described.
  
  
  RESULTS
  The clinical features, histopathological findings and immunohistochemical study are presented.
  
  
  CONCLUSIONS
  Both cases previously had cystic glandular cystitis, which supports the totipotent urothelium origin of this neoplasm. Signet-ring cell adenocarcinoma or linitis plastica of the bladder has a highly malignant course despite neoadjuvant chemotherapy and total cystectomy.
authors.affiliation: Departamento de Anatomía Patológica, Ciudad Sanitaria Vall d'Hebron, Barcelona, España.
authors.forename: C
authors.initials: C
authors.lastname: González Mínguez
authors.forename: I
authors.initials: I
authors.lastname: de Torres Ramírez
authors.forename: R
authors.initials: R
authors.lastname: Bosch Princep
authors.forename: J I
authors.initials: JI
authors.lastname: Idoipe Tomás
mesh_terms: D018279:Carcinoma, Signet Ring Cell / Q000473:pathology*; D006801:Humans; D008039:Linitis Plastica / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000473:pathology*
vernacular_title: Adenocarcinoma de células en anillo de sello primario de vejiga. Presentación de dos casos de linitis plástica vesical.