False positive pleural biopsy and high CA125 levels in serum and pleural effusion in systemic lupus erythematosus.
A 23-year-old female with systemic lupus erythematosus is reported. The clinical features included fever, shortness of breath, lymphadenopathies, hepatosplenomegaly, pleural and pericardial fluids, ANA and Anti-DNA positivity. Pleural biopsy was false positive for malignancy on two occasions. High CA125 levels were detected in both serum and pleural fluid. Following prednisolone treatment, clinical and laboratory findings returned to normal.
Yucel
A E
AE
Department of Rheumatology, Hacettepe University, Ankara, Turkey.
Calguneri
M
M
Ruacan
S
S
D000328:Adult; D000974:Antibodies, Antinuclear / Q000097:blood; D001707:Biopsy, Needle; D018394:CA-125 Antigen / Q000097:blood*; D005122:Exudates and Transudates; D005189:False Positive Reactions; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D010994:Pleura / Q000473:pathology*; D010996:Pleural Effusion / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use; D011860:Radiography, Abdominal; D014057:Tomography, X-Ray Computed
D000974:Antibodies, Antinuclear; D018394:CA-125 Antigen; D005938:Glucocorticoids; D011239:Prednisolone