Trauma, shock, and gut translocation.
This article reviews the scientific and clinical evidence that supports trauma and shock as potential etiologies for translocation of intestinal microorganisms and their by-products. The potential for loss of intestinal barrier function to cause the eventual septic deaths observed in such patients, as well as possible mechanisms for preventing and treating this entity is also discussed.
Deitch
E A
EA
Department of Surgery, UMDNJ-New Jersey Medical School, Newark 07103-2714, USA.
Rutan
R
R
Waymack
J P
JP
D000818:Animals; D018988:Bacterial Translocation; D002056:Burns / Q000382:microbiology; D006801:Humans; D007422:Intestines / Q000382:microbiology*; D009102:Multiple Organ Failure / Q000382:microbiology; D018805:Sepsis / Q000209:etiology / Q000382:microbiology*; D012769:Shock / Q000150:complications / Q000382:microbiology*; D014947:Wounds and Injuries / Q000150:complications / Q000382:microbiology*