[The effect of controllable and uncontrollable stressor actions on dexamethasone receptor binding in the hypophysis and hippocampus of rats with different behavioral strategies].
Exposure to inescapable foot shocks (ISs) decreased the dexamethasone receptor binding in the KHA rat hippocampus. Both the ISs and escapable foot shocks (ESs) enhanced the binding in the pituitary of the KLA rats as well as their plasma corticosterone. The data obtained suggest that the brain corticosteroid binding depends on the coping style of the subject as well as on the stress controllability factor.
Ordian
N E
NE
Zhukov
D A
DA
D000818:Animals; D001522:Behavior, Animal / Q000502:physiology*; D001923:Brain Chemistry / Q000502:physiology; D003345:Corticosterone / Q000097:blood; D003600:Cytosol / Q000737:chemistry / Q000378:metabolism; D003907:Dexamethasone / Q000032:analysis / Q000378:metabolism*; D004558:Electric Stimulation; D006624:Hippocampus / Q000737:chemistry / Q000378:metabolism*; D008297:Male; D010902:Pituitary Gland / Q000737:chemistry / Q000378:metabolism*; D011869:Radioligand Assay; D051381:Rats; D011919:Rats, Inbred Strains; D011965:Receptors, Glucocorticoid / Q000032:analysis / Q000378:metabolism*; D013312:Stress, Physiological / Q000378:metabolism*
D011965:Receptors, Glucocorticoid; C028697:dexamethasone receptor; D003907:Dexamethasone; D003345:Corticosterone
Vliianie kontroliruemogo i nekontroliruemogo stressornykh vozdeĭstviĭ na retseptornoe sviazyvanie deksametazona v gipofize i gippokampe krys s razlichnoĭ strategieĭ povedeniia.