title: Overexpression of vsr in Escherichia coli is mutagenic.
abstract: Overexpression of vsr in Escherichia coli stimulates transition and frameshift mutations. The pattern of mutations suggests that mutagenesis is due to saturation or inactivation of dam-directed mismatch repair.
authors.affiliation: Biology Department, Concordia University, Montréal, Québec, Canada.
authors.forename: K M
authors.initials: KM
authors.lastname: Doiron
authors.forename: S
authors.initials: S
authors.lastname: Viau
authors.forename: M
authors.initials: M
authors.lastname: Koutroumanis
authors.forename: C G
authors.initials: CG
authors.lastname: Cupples
mesh_terms: D004260:DNA Repair / Q000235:genetics*; D004706:Endodeoxyribonucleases / Q000096:biosynthesis*; D004926:Escherichia coli / Q000235:genetics*; D016368:Frameshift Mutation; D016296:Mutagenesis / Q000235:genetics*
chemical_list: D004706:Endodeoxyribonucleases; C071421:vsr endonuclease