title: [Retroperitoneal extragonadal germinal choriocarcinoma: description of a case and the complex therapeutic approach].
abstract: Patients with primary extragonadal, retroperitoneal germ cell tumors usually have very advanced disease and present uncharacteristic signs and symptoms. We report a case of a patient with large retroperitoneal choriocarcinoma. After four initial cycles of chemotherapy, the patient underwent debulking surgery including angiorrhaphy and-plasty. This therapeutic management was justified, as it revealed active residual tumor. Furthermore, a large tumor mass was removed with vascular and ureteric decompression. As a result of this treatment, adjuvant chemotherapy was more effective. In conclusion, despite possible complications, we recommend this regimen in young patients.
authors.affiliation: Klinik für Urologie und Kinderurologie, Universität des Saarlandes, Homburg/Saar.
authors.forename: T
authors.initials: T
authors.lastname: Lindenmeir
authors.forename: S
authors.initials: S
authors.lastname: Giacchi
authors.forename: B
authors.initials: B
authors.lastname: Wullich
authors.forename: T
authors.initials: T
authors.lastname: Zwergel
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000097:blood; D001706:Biopsy; D017024:Chemotherapy, Adjuvant; D002822:Choriocarcinoma / Q000175:diagnosis* / Q000601:surgery*; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D006801:Humans; D008297:Male; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D000509:alpha-Fetoproteins / Q000737:chemistry
chemical_list: D014408:Biomarkers, Tumor; D018997:Chorionic Gonadotropin, beta Subunit, Human; D000509:alpha-Fetoproteins
vernacular_title: Chorio-carcinome germinal extragonadique à localisation rétropéritonéale: description d'un cas et de sa conception thérapeutique complexe.