Rasmussen's encephalitis: an autoimmune disorder?
Rasmussen's encephalitis is a rare progressive pediatric epileptic syndrome. Recent evidence from experimental animals and patients with the disease suggests an important role for both humoral- and cell-mediated immune mechanisms in the pathogenesis of this disease. The glutamate receptor subunit, GluR3, may be an important autoantigen in the disease.
Andrews
P I
PI
The Duke Center for the Advanced Study of Epilepsy, Durham, NC, USA.
McNamara
J O
JO
D001327:Autoimmune Diseases / Q000503:physiopathology*; D017036:Epilepsia Partialis Continua / Q000503:physiopathology*; D006801:Humans