title: Therapy of gonadal stromal cell testicular tumours.
abstract: At our regional centre, 504 patients with testicular tumour were treated from 1 January 1980 to 31 December 1993. In the course of the treatment, 10 patients (2%) with gonadal stromal cell testicular tumours were found. Histopathological examination identified Sertoli cells in 3 cases, granulosa cells in 1 case, and Leydig cell primary tumours in 6 cases. Leydig cell testicular tumours, the most significant clinically, should not be regarded as benign. In 3 of 6 cases metastatic processes developed. Three patients died in spite of the surgical and chemotherapeutic interventions. Analysis of these cases suggests that, following the semicastration of Leydig cell testicular tumours, a primary retroperitoneal lymph node dissection should be performed, and an exact identification of the pathological stage should be carried out.
authors.affiliation: Urological Institute of the Medical School, Pécs, Hungary.
authors.forename: L
authors.initials: L
authors.lastname: Farkas
authors.forename: M
authors.initials: M
authors.lastname: Baki
authors.forename: C
authors.initials: C
authors.lastname: Pusztai
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D017154:Stromal Cells / Q000473:pathology*; D013736:Testicular Neoplasms / Q000473:pathology* / Q000628:therapy*