title: Ulcerative colitis in children under 10 years of age: medical and surgical treatment.
abstract: Ulcerative colitis is seen with increasing frequency in paediatric age and its diagnosis is made more difficult by atypical cases. Sixty-five patients with UC were seen at our institute and all of them underwent medical treatment. In all patients the disease extended to the whole colon (pancolitis). Eleven patients (average age 9 yrs) underwent surgical correction by Endorectal Pull Through (EPT) 8 straight and 3 with ileal reservoir. One straight EPT had to be converted to Brooke ileostomy because of unacceptable stool frequency. In the rest of the patients the disease is well controlled with medical treatment. After 2 years of follow up surgical complications, continence, stool frequency and quality of life were evaluated: results indicate that surgical complications rate is the same as in other reported series; furthermore, continence and stool frequency are good with all surgical techniques eve though straight pull-through may require a period of adaptation the length of which varies considerably. Our results confirm that children with pancolitis and severe symptoms should be offered prolonged medical treatment prior to undertake surgical correction.
authors.affiliation: Department of Paediatric Surgery and Gastroenterology Bambino Gesù Children's Hospital Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Rivosecchi
authors.forename: M C
authors.initials: MC
authors.lastname: Lucchetti
authors.forename: L
authors.initials: L
authors.lastname: Dall'Oglio
authors.forename: A
authors.initials: A
authors.lastname: Ponticelli
authors.forename: G
authors.initials: G
authors.lastname: Federici
authors.forename: A
authors.initials: A
authors.lastname: Zaccara
authors.forename: F
authors.initials: F
authors.lastname: Ferretti
authors.forename: M
authors.initials: M
authors.lastname: Castro
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003093:Colitis, Ulcerative / Q000188:drug therapy* / Q000601:surgery*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007081:Ileostomy; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008297:Male; D016737:Proctocolectomy, Restorative
chemical_list: D007166:Immunosuppressive Agents