title: Swayback in a blesbok (Damaliscus dorcas phillipsi) and a black wildebeest (Connochaetes gnou).
abstract: Ataxia associated with myelopathy and low liver copper concentrations is described in a blesbok (Damaliscus dorcas phillipsi) and black wildebeest (Connochaetes gnou) from the Karoo Nature Reserve, Graaff-Reinet. This syndrome, which occurs in neonatal and delayed forms, has been described in sheep, goats, pigs and domesticated red deer, but reports in other ungulates, including antelope, are very rare and generally unconfirmed by histopathological examination. The 2 animals examined exhibited a typical pattern of Wallerian degeneration in selected tracts of the spinal cord. Many blesbok in the reserve are markedly pale in colour. Fading of the hair is also associated with copper deficiency in ungulates. High lamb mortality occurs as a result of the ataxia and threatens the survival of the blesbok herd in the reserve. Confirmation of low liver copper concentrations in affected animals offers direction towards the solution of the problem.
authors.affiliation: Pathology Section, Onderstepoort Veterinary Institute, South Africa.
authors.forename: M L
authors.initials: ML
authors.lastname: Penrith
authors.forename: R C
authors.initials: RC
authors.lastname: Tustin
authors.forename: D J
authors.initials: DJ
authors.lastname: Thornton
authors.forename: P D
authors.initials: PD
authors.lastname: Burdett
mesh_terms: D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D000866:Antelopes / Q000378:metabolism*; D001259:Ataxia / Q000473:pathology / Q000662:veterinary; D001921:Brain / Q000378:metabolism / Q000473:pathology; D003300:Copper / Q000172:deficiency*; D004044:Dietary Proteins / Q000378:metabolism; D005260:Female; D007668:Kidney / Q000378:metabolism / Q000473:pathology; D008099:Liver / Q000378:metabolism / Q000473:pathology; D008297:Male; D012756:Sheep; D013019:South Africa; D013116:Spinal Cord / Q000378:metabolism / Q000473:pathology; D013540:Swayback / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology
chemical_list: D004044:Dietary Proteins; D003300:Copper