Methodological issues in the design of primary prevention trials.
Gaziano
J M
JM
Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215-1204, USA.
Hennekens
C H
CH
Buring
J E
JE
D016588:Anticarcinogenic Agents / Q000627:therapeutic use; D018890:Chemoprevention / Q000379:methods*; D004311:Double-Blind Method; D006801:Humans; D009369:Neoplasms / Q000517:prevention & control*; D010919:Placebos; D016032:Randomized Controlled Trials as Topic / Q000379:methods*; D019207:beta Carotene / Q000627:therapeutic use
D016588:Anticarcinogenic Agents; D010919:Placebos; D019207:beta Carotene