title: Hypergastrinemia following gastrocystoplasty in rats.
abstract: Gastrocystoplasty has been previously described as an effective method of bladder augmentation or replacement. Twenty-four female Wistar rats were divided into three groups of eight animals each: control (G1), partial gastrectomy with the gastric body (G2) and gastrocystoplasty with the gastric body (G3). The period of observation was 2 months and the parameter assessed was serum gastrin. Increases in serum gastrin were seen in 62.5% (5/8) of rats in group 2 and in 50% (4/8) of rats in group 3. Our results suggest that, in rats, hypergastrinemia is induced by the partial surgical removal of the gastric body and is not due to gastrocystoplasty.
authors.affiliation: Department of Surgery, Escola Puulista de Medicina, São Paulo, Brazil.
authors.forename: V
authors.initials: V
authors.lastname: Ortiz
authors.forename: S
authors.initials: S
authors.lastname: Goldenberg
mesh_terms: D000818:Animals; D005260:Female; D005753:Gastric Mucosa / Q000378:metabolism / Q000601:surgery; D005755:Gastrins / Q000097:blood*; D009929:Organ Size; D051381:Rats; D017208:Rats, Wistar; D013270:Stomach / Q000601:surgery*; D001743:Urinary Bladder / Q000601:surgery*; D014549:Urinary Incontinence / Q000601:surgery; D016476:Urinary Reservoirs, Continent / Q000379:methods
chemical_list: D005755:Gastrins