Practical methods of mutation detection.
The past few years have seen a marked increase in the demand for practical methods of mutation detection. Over this period of time, both the development of new methods and improvements in existing methods have made mutation detection in the research setting a less cumbersome task. Nevertheless, all of the commonly used approaches to this problem are labor intensive, and truly practical mutation detection methods in the clinical setting will depend on the development of more fully automated technology.
Mashal
R D
RD
Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Sklar
J
J
D004252:DNA Mutational Analysis; D005544:Forecasting; D005821:Genetic Techniques; D006801:Humans; D009154:Mutation; D009690:Nucleic Acid Conformation; D017422:Sequence Analysis, DNA