title: A simian varicella virus (SVV) homolog to varicella-zoster virus gene 21 is expressed in monkey ganglia latently infected with SVV.
abstract: We have sequenced a simian varicella virus (SVV) open reading frame (ORF), 3,123 bp in length, whose product has 51% amino acid homology with the sequence encoded by the ORF of varicella-zoster virus gene 21. Several regions are highly conserved between the two ORFs, with homologies of approximately 80%. The SVV gene is transcribed in tissue culture cells productively infected with SVV and in monkey ganglia latently infected with SVV.
authors.affiliation: Department of Neurology, University of Colorado Health Sciences Center, Denver 80262, USA.
authors.forename: P
authors.initials: P
authors.lastname: Clarke
authors.forename: W L
authors.initials: WL
authors.lastname: Matlock
authors.forename: T
authors.initials: T
authors.lastname: Beer
authors.forename: D H
authors.initials: DH
authors.lastname: Gilden
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D005724:Ganglia / Q000821:virology*; D000882:Haplorhini; D006566:Herpesviridae Infections / Q000473:pathology / Q000821:virology*; D006568:Herpesvirus 1, Cercopithecine / Q000235:genetics / Q000302:isolation & purification*; D014645:Herpesvirus 3, Human; D006801:Humans; D008969:Molecular Sequence Data