title: Comparison of total intravenous, balanced inhalational and combined intravenous-inhalational anaesthesia for tympanoplasty, septorhinoplasty and adenotonsillectomy.
abstract: Two hundred and thirty-five consecutive Saudi patients aged between two and fifty-three years undergoing elective tympanoplasty (n = 32), septorhinoplasty (n = 68) or adenotonsillectomy (n = 135) were studied. They were randomized to receive either a total intravenous anaesthetic (10 ears, 23 noses, 44 throats) consisting of propofol for induction of anaesthesia followed by a propofol infusion, a combined intravenous-inhalational anaesthetic (11 ears, 22 noses, 46 throats) consisting of the above with isoflurane in oxygen-enriched air, or a balanced inhalational anaesthetic (11 ears, 23 noses, 45 throats) consisting of thiopentone for induction of anaesthesia and oxygen in nitrous oxide with isoflurane for maintenance. During tympanoplasty, all three anaesthetic techniques produced stable heart rates and arterial pressures. During septorhinoplasty, blood pressure rose in patients who received total intravenous anaesthesia, while combined and balanced techniques produced haemodynamic stability. During adenotonsillectomy, total intravenous anaesthesia produced a rise in both heart rate and blood pressure, the combined technique produced a rise in heart rate alone while balanced anaesthesia produced haemodynamic stability. Postoperatively, vomiting, pain scores and analgesic requirements were similar following all three types of anaesthetic within each surgical site subgroup. Our findings support the choice of balanced inhalational anaesthesia for all three types of ENT surgery and, where cost and facilities permit, total intravenous anaesthesia for tympanoplasty and combined intravenous-inhalational anaesthesia for septorhinoplasty.
authors.affiliation: Dept of Anaesthesia, Armed Forces Hospital, Riyadh, Kingdom of Saudi Arabia.
authors.forename: A A
authors.initials: AA
authors.lastname: Van den Berg
authors.forename: D
authors.initials: D
authors.lastname: Savva
authors.forename: N M
authors.initials: NM
authors.lastname: Honjol
authors.forename: N V
authors.initials: NV
authors.lastname: Prabhu
mesh_terms: D000233:Adenoidectomy; D000293:Adolescent; D000328:Adult; D000769:Anesthesia, Inhalation / Q000009:adverse effects; D000771:Anesthesia, Intravenous / Q000009:adverse effects; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D001794:Blood Pressure; D002648:Child; D002675:Child, Preschool; D005260:Female; D006261:Headache / Q000209:etiology; D006339:Heart Rate; D006801:Humans; D007530:Isoflurane; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy; D015742:Propofol; D012225:Rhinoplasty; D014068:Tonsillectomy; D014433:Tympanoplasty; D014839:Vomiting / Q000209:etiology
chemical_list: D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D007530:Isoflurane; D015742:Propofol