title: Improvement of hemolysis in muscle phosphofructokinase deficiency by restriction of exercise.
abstract: A 29-year-old woman with muscle phosphofructokinase (PFK) deficiency had exercise intolerance, painful cramps, elevation of muscle enzyme levels in the serum and compensated hemolysis. After the restriction of exercise, the creatine kinase level and indirect bilirubin level decreased, and the reticulocyte count and haptoglobin level were normalized. It is suggested that the hemolysis which was accelerated by exercise was improved by restriction of exercise.
authors.affiliation: Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya.
authors.forename: H
authors.initials: H
authors.lastname: Toyoda
authors.forename: T
authors.initials: T
authors.lastname: Nakase
authors.forename: M
authors.initials: M
authors.lastname: Tomeoku
authors.forename: K
authors.initials: K
authors.lastname: Morita
authors.forename: M
authors.initials: M
authors.lastname: Kato
authors.forename: T
authors.initials: T
authors.lastname: Murata
authors.forename: A
authors.initials: A
authors.lastname: Ono
authors.forename: M
authors.initials: M
authors.lastname: Kuwajima
authors.forename: N
authors.initials: N
authors.lastname: Kono
mesh_terms: D000328:Adult; D001663:Bilirubin / Q000097:blood; D001706:Biopsy; D003402:Creatine Kinase / Q000097:blood; D004912:Erythrocytes / Q000201:enzymology; D015444:Exercise / Q000502:physiology; D005080:Exercise Test; D005260:Female; D006003:Glycogen / Q000648:ultrastructure; D006014:Glycogen Storage Disease Type VII / Q000097:blood / Q000209:etiology / Q000503:physiopathology*; D006461:Hemolysis / Q000502:physiology*; D006801:Humans; D018482:Muscle, Skeletal / Q000201:enzymology* / Q000648:ultrastructure; D010732:Phosphofructokinase-1 / Q000097:blood / Q000172:deficiency*
chemical_list: D006003:Glycogen; D010732:Phosphofructokinase-1; D003402:Creatine Kinase; D001663:Bilirubin