[Progressive lupus dementia. 2 cases with or without antiphospholipid antibodies].
Two cases of lupus dementia presented many points of particular interest: 1) the progressive installation of intellectual deterioration, inaugural for the first observation; 2) the diagnostic difficulties of neurolupus with the ARA criteria; 3) the appearance of cerebral magnetic resonance imaging with confluent hypersignals of the periventricular white matter on T2-weighted images; 4) the patholophysiological hypotheses: vascular disease? immunologic disease?; 5) the clinical improvement and SPECT amelioration for the second patient with corticosteroids.
Robin
C
C
Service de Neurologie, Hôpital Neurologique Pierre Wertheimer, Lyon.
Gonnaud
P M
PM
Durieu
I
I
Croisile
B
B
Garassus
P
P
Levrat
R
R
Chazot
G
G
Aimard
G
G
Trillet
M
M
D017152:Antibodies, Antiphospholipid / Q000032:analysis*; D003704:Dementia / Q000209:etiology* / Q000276:immunology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000276:immunology; D008875:Middle Aged; D013997:Time Factors
D017152:Antibodies, Antiphospholipid
Démence lupique progressive. Deux cas avec anticorps antiphospholipides ou non.