title: Specific IgE against milk allergens in children with insulin dependent diabetes mellitus.
abstract: Cow's milk has been considered as a possible trigger of the autoimmune response that destroys pancreatic B-cells, thus causing insulin dependent diabetes mellitus. We investigated 46 children with IDDM. In this group we showed an increased total IgE in 58.6% of cases and the presence of specific IgE antibodies induced by milk allergens in 32.5% of cases. These results suggests that antibodies probably play an important role in IDDM pathogenesis.
authors.affiliation: Department of Pediatrics and Allergology, Medical Academy of Wrocław.
authors.forename: A
authors.initials: A
authors.lastname: Boznański
authors.forename: I
authors.initials: I
authors.lastname: Pirogowicz
authors.forename: R
authors.initials: R
authors.lastname: Wasik
authors.forename: E
authors.initials: E
authors.lastname: Barg
authors.forename: A
authors.initials: A
authors.lastname: Hebrowska
mesh_terms: D000293:Adolescent; D000485:Allergens; D000818:Animals; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D008297:Male; D008892:Milk / Q000276:immunology*
chemical_list: D000485:Allergens; D007073:Immunoglobulin E