[Cutaneous pigmentation, only manifestation of porphyria cutanea tarda in a HIV-1 positive patient].
BACKGROUND
Porphyria cutanea tarda (PCT) is an unfrequent disorder in patients with acquired immunodeficiency syndrome (AIDS) due to deficiency in uroporphyrinogen decarboxilase. The more frequent cutaneous manifestations are skin fragility and hypertrichosis.


METHODS
A 44-years-old man with AIDS presented an intense cutaneous hyperpigmentation, preferently involving sun-exposed areas. Histopathologic studies showed perivascular PAS-positive deposits. Biochemical studies confirmed the diagnosis of PCT.


CONCLUSIONS
PCT should be included in the differential diagnosis of cutaneous hyperpigmentation in patients infected by human immunodeficiency virus (HIV).
Pascual
C
C
Servicios de Dermatología, Hospital General Universitari Vall d'Hebron, Barcelona, España.
García-Patos
V
V
Bartralot
R
R
Pedragosa
R
R
Capdevila
M
M
Barberá
J
J
Castells
A
A
D000328:Adult; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1; D006526:Hepatitis C / Q000150:complications; D006801:Humans; D017495:Hyperpigmentation / Q000209:etiology* / Q000473:pathology; D008297:Male; D010787:Photosensitivity Disorders / Q000209:etiology; D017119:Porphyria Cutanea Tarda / Q000209:etiology* / Q000473:pathology
Pigmentation cutanée, seule manifestation d'une porphyrie cutanée tardive chez un malade séropositif pour le VIH1.