title: Ileal pouch anal function after endoanal mucosectomy and handsewn ileoanal anastomosis compared with stapled anastomosis without mucosectomy.
abstract: OBJECTIVE
  To compare manovolumetric results and functional outcome after restorative proctocolectomy with either mucosal proctectomy and handsewn pouch-anal anastomosis or stapling.
  
  
  METHODS
  Prospective randomised study.
  
  
  METHODS
  University hospital, Sweden.
  
  
  METHODS
  80 Consecutive patients undergoing restorative proctocolectomy.
  
  
  METHODS
  37 patients were randomised to have mucosectomy and a handsewn anastomosis and 43 patients to have a stapled anastomosis.
  
  
  METHODS
  Comparisons of anal sphincter function and clinical outcome in terms of continence and overall functional score between the two groups of patients.
  
  
  RESULTS
  There was persistent reduction in anal resting tone at one year amounting to 29% in the handsewn group and and to 21% in the stapled group (p < 0.001 compared with preoperative in both groups). Daytime continence was similar, but patients with stapled anastomoses experienced less soiling during sleep, especially in the early postoperative period (5/43, 12% compared with 15/33, 45% at one month, p < 0.001). The arbitrary overall functional score was, however, similar in both groups.
  
  
  CONCLUSIONS
  Handsewn and stapled ileal pouch-anal anastomoses result in similar postoperative anal sphincter impairment and overall clinical outcome.
authors.affiliation: Department of Surgery, University of Göteborg, Sweden.
authors.forename: T A
authors.initials: TA
authors.lastname: Hallgren
authors.forename: S B
authors.initials: SB
authors.lastname: Fasth
authors.forename: T O
authors.initials: TO
authors.lastname: Oresland
authors.forename: L A
authors.initials: LA
authors.lastname: Hultén
mesh_terms: D000293:Adolescent; D000328:Adult; D001003:Anal Canal / Q000502:physiology; D000714:Anastomosis, Surgical / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011184:Postoperative Period; D011312:Pressure; D016737:Proctocolectomy, Restorative / Q000379:methods*; D011446:Prospective Studies; D017792:Surgical Stapling; D016896:Treatment Outcome