Erratum to 'HmGlu1d, a novel splice variant of the human type I metabotropic glutamate receptor' [Eur. J. pharmacol. 296 (1996) R1-R3].
A novel splice variant, hmGlu1d, of the human mGlu1 metabotropic glutamate receptor has been isolated from a human brain library. This clone is identical to human mGlu1a except that it lacks 35 nucleotides in the 3' coding sequence, which predicts a truncated protein and a novel carboxy terminus. After injection of the encoding sequence into mouse A9 fibroblasts, quisqualate and (1S, 3R)-aminocyclopentane-1, 3-dicarboxylic acid ((1S,3R)-ACPD) elicited concentration-dependent increases in intracellular Ca2+ (pEC50 values of 6.09 and 4.33, respectively).
Laurie
D J
DJ
Sandoz Pharma AG, Preclinical Research, Basle, Switzerland.
Boddeke
H W
HW
Hiltscher
R
R
Sommer
B
B
D000818:Animals; D001483:Base Sequence; D006801:Humans; D051379:Mice; D008969:Molecular Sequence Data; D017470:Receptors, Glutamate / Q000235:genetics*
D017470:Receptors, Glutamate