Spinal cord ependymoma: a positron emission tomographic study with (11C-methyl)-L-methionine.
An intramedullary spinal cord ependymoma was studied by positron emission tomography (PET) using (11C-methyl)-L-methionine (11C-Met). MRI showed a homogeneously enhancing tumour at C6-T2 with cysts at its rostral and caudal ends. Sagittal PET images demonstrated high 11C-Met uptake in the solid portion of the tumour, particularly ventrally at C7-T2, where viable tumour cells proliferated in association with abundant perforating vessels. Met-PET would appear useful for delineating the viable portion of intramedullary ependymomas.
Sasajima
T
T
Neurosurgical Service, Akita University Hospital, Japan.
Mineura
K
K
Itoh
Y
Y
Kowada
M
M
Hatazawa
J
J
Ogawa
T
T
Uemura
K
K
D000368:Aged; D002250:Carbon Radioisotopes / Q000493:pharmacokinetics; D004806:Ependymoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008715:Methionine / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D013116:Spinal Cord / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D013120:Spinal Cord Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D014022:Tissue Survival / Q000502:physiology; D014055:Tomography, Emission-Computed
D002250:Carbon Radioisotopes; D008715:Methionine; C038344:methionine methyl ester