[Bladder and sphincter disorders in multiple sclerosis. Clinical, urodynamic and neurophysiological study of 225 cases].
Two hundred and twenty-five patients with multiple sclerosis and bladder dysfunction were evaluated. 72% had urinary incontinence, 46% dysuria and 24% urinary retention. Detrusor hyperreflexia was the most common finding on cystometry (70%) and 9% of patients had areflexia. Coaxial needle electromyography was performed on all patients and 82% had detrusor-sphincter dyssynergia. Cortical evoked potentials following stimulation of the pudendal nerve were delayed in 72% and sacral evoked latency in 16% especially in patients with incontinence secondary to overactive bladder (25%), suggesting a conus medullaris lesion in these cases. Urologic complications were noted in 40%, with benign lesions in 24% (diverticula, urinary infections) and serious lesions in 16% (hydronephrosis, pyelonephritis, renal reflux). The most common treatment was anticholinergic drugs (efficacy in 92%), alphablockers agents (efficacy in 60%) and autocatheterism in 28%.
Amarenco
G
G
Laboratoire d'Urodynamique et de Neurophysiologie, Aulnay-sous-Bois.
Kerdraon
J
J
Denys
P
P
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications* / Q000503:physiopathology; D009482:Neurophysiology; D001745:Urinary Bladder Diseases / Q000209:etiology* / Q000503:physiopathology; D014555:Urination Disorders / Q000209:etiology / Q000503:physiopathology; D014563:Urodynamics
Les troubles vésico-sphinctériens de la sclérose en plaques. Etude clinique, urodynamique et neurophysiologique de 225 cas.