title: Determination of bioconcentration factors of eight tetrachlorobenzyltoluenes in the zebra mussel Dreissena polymorpha.
abstract: Accurate duplicate bioconcentration factors were determined for tetrachlorobenzyltoluenes (TCBTs). This is the first study that quantifies bioconcentration factors for single TCBT isomers. A continuous flow uptake experiment was performed during 21 days with the zebra mussel (Dreissena polymorpha) as a test organism. Bioconcentration factors (BCFs) and rate constants were derived by an iterative integration method. With this method BCFs and rate constants can be derived from experimental data of a bio-concentration test, even if the concentration in the water is not constant and steady state has not been reached. Mean log BCF values of TCBTs ranged from 4.43 +/- 0.05 to 5.19 +/- 0.15 liter.kg-1 on a wet weight basis. The experimental log BCF values were compared with log BCF values of TCBTs, calculated according to linear and polynomial relationships between log BCF and log Kow.
authors.affiliation: Department of Environmental and Toxicological Chemistry, Amsterdam Research Institute for Substances in Ecosystems, University of Amsterdam, The Netherlands.
authors.forename: A G
authors.initials: AG
authors.lastname: van Haelst
authors.forename: Q
authors.initials: Q
authors.lastname: Zhao
authors.forename: F W
authors.initials: FW
authors.lastname: van der Wielen
authors.forename: H A
authors.initials: HA
authors.lastname: Govers
authors.forename: P
authors.initials: P
authors.lastname: de Voogt
mesh_terms: D000818:Animals; D001559:Benzhydryl Compounds / Q000378:metabolism / Q000633:toxicity*; D049872:Bivalvia / Q000378:metabolism*; D002849:Chromatography, Gas; D006843:Hydrocarbons, Chlorinated / Q000378:metabolism / Q000633:toxicity*; D007700:Kinetics; D011078:Polychlorinated Biphenyls / Q000032:analysis / Q000378:metabolism*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D001559:Benzhydryl Compounds; D006843:Hydrocarbons, Chlorinated; D014874:Water Pollutants, Chemical; D011078:Polychlorinated Biphenyls