Spiral laminar flow in vivo.
1. Blood flow patterns are poorly understood despite their impact on arterial disease. There have been few measurements in vivo of the three-dimensional blood flow patterns; we present the results of such studies using a new non-invasive in-vivo method of examining biplanar arterial blood flow patterns. 2. Multiple colour Doppler ultrasound directional velocity images were obtained at two different beam target angles from the artery in the plane perpendicular to its axis. Ensemble average images were constructed; the absolute velocity and direction were calculated by compounding the left and right averaged images. Simple directional, non-directional velocity and vector maps were constructed. 3. Flow patterns were sampled in 11 healthy male volunteers at four points of the pulse cycle; peak systole, systolic downswing, diastolic reverse flow and diastolic forward flow and at three sites; the right common and distal superficial femoral and the left common femoral arteries. 4. Stable rotational flow was observed in all subjects, the direction of rotation varying between sides and individuals. 5. There are theoretical advantages to spiral laminar blood flow; the forward-directed, rotationally induced stability and reduction of laterally directed forces may reduce turbulence in the tapering branching arterial tree and at stenoses and have a beneficial effect on mechanisms of endothelial damage and repair.
Stonebridge
P A
PA
Department of Surgery and Medicine, Ninewells Hospital, Dundee, U.K.
Hoskins
P R
PR
Allan
P L
PL
Belch
J F
JF
D001783:Blood Flow Velocity; D003971:Diastole / Q000502:physiology; D005263:Femoral Artery / Q000000981:diagnostic imaging* / Q000502:physiology; D018056:Hemorheology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D012399:Rotation; D013599:Systole / Q000502:physiology; D018615:Ultrasonography, Doppler, Color