title: Role of translation initiation factor eIF-2B in the regulation of protein synthesis in mammalian cells.
authors.affiliation: Department of Cellular and Molecular Physiology, College of Medicine, Pennsylvania State University, Hershey 17033, USA.
authors.forename: S R
authors.initials: SR
authors.lastname: Kimball
authors.forename: H
authors.initials: H
authors.lastname: Mellor
authors.forename: K M
authors.initials: KM
authors.lastname: Flowers
authors.forename: L S
authors.initials: LS
authors.lastname: Jefferson
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics; D005656:Fungal Proteins / Q000737:chemistry; D005786:Gene Expression Regulation; D020662:Guanine Nucleotide Exchange Factors; D008322:Mammals / Q000235:genetics; D051379:Mice; D008969:Molecular Sequence Data; D010442:Peptide Chain Initiation, Translational; D010766:Phosphorylation; D014176:Protein Biosynthesis; D011499:Protein Processing, Post-Translational; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D011506:Proteins / Q000737:chemistry / Q000235:genetics / Q000502:physiology*; D011817:Rabbits; D051381:Rats; D012441:Saccharomyces cerevisiae / Q000235:genetics; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity; D013329:Structure-Activity Relationship; D019892:eIF-2 Kinase
chemical_list: D018076:DNA, Complementary; D005656:Fungal Proteins; D020662:Guanine Nucleotide Exchange Factors; D011506:Proteins; D017346:Protein Serine-Threonine Kinases; D019892:eIF-2 Kinase