title: (S)-(-)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine maleate (SIB-1508Y): a novel anti-parkinsonian agent with selectivity for neuronal nicotinic acetylcholine receptors.
authors.affiliation: SIBIA Neurosciences Inc., La Jolla, California 92037, USA.
authors.forename: N D
authors.initials: ND
authors.lastname: Cosford
authors.forename: L
authors.initials: L
authors.lastname: Bleicher
authors.forename: A
authors.initials: A
authors.lastname: Herbaut
authors.forename: J S
authors.initials: JS
authors.lastname: McCallum
authors.forename: J M
authors.initials: JM
authors.lastname: Vernier
authors.forename: H
authors.initials: H
authors.lastname: Dawson
authors.forename: J P
authors.initials: JP
authors.lastname: Whitten
authors.forename: P
authors.initials: P
authors.lastname: Adams
authors.forename: L
authors.initials: L
authors.lastname: Chavez-Noriega
authors.forename: L D
authors.initials: LD
authors.lastname: Correa
authors.forename: J H
authors.initials: JH
authors.lastname: Crona
authors.forename: L S
authors.initials: LS
authors.lastname: Mahaffy
authors.forename: F
authors.initials: F
authors.lastname: Menzaghi
authors.forename: T S
authors.initials: TS
authors.lastname: Rao
authors.forename: R
authors.initials: R
authors.lastname: Reid
authors.forename: A I
authors.initials: AI
authors.lastname: Sacaan
authors.forename: E
authors.initials: E
authors.lastname: Santori
authors.forename: K A
authors.initials: KA
authors.lastname: Stauderman
authors.forename: K
authors.initials: K
authors.lastname: Whelan
authors.forename: G K
authors.initials: GK
authors.lastname: Lloyd
authors.forename: I A
authors.initials: IA
authors.lastname: McDonald
mesh_terms: D000818:Animals; D000978:Antiparkinson Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D002460:Cell Line; D005260:Female; D006801:Humans; D007700:Kinetics; D015394:Molecular Structure; D009474:Neurons / Q000502:physiology*; D009865:Oocytes / Q000502:physiology; D018408:Patch-Clamp Techniques; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D011978:Receptors, Nicotinic / Q000187:drug effects / Q000502:physiology*; D011994:Recombinant Proteins / Q000187:drug effects / Q000378:metabolism; D013237:Stereoisomerism; D014981:Xenopus
chemical_list: D000978:Antiparkinson Agents; D011725:Pyridines; D011759:Pyrrolidines; D011978:Receptors, Nicotinic; D011994:Recombinant Proteins; C100989:altinicline maleate