[The opiate-like and antimicrobial bioactivities of food protein peptides].
At least four food peptides were found to possess opiate-like and antibacterial properties, lys-arg-fen-ala-glu being the most active one. These peptides seem to be able to become accumulated in high concentrations in indigestion and induce an intestinal spasm and constipation.
Kharchenko
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D000595:Amino Acid Sequence; D000701:Analgesics, Opioid / Q000494:pharmacology*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D004044:Dietary Proteins / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D007420:Intestine, Large / Q000187:drug effects / Q000382:microbiology; D051379:Mice; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D017288:Pain Threshold / Q000187:drug effects / Q000502:physiology; D010455:Peptides / Q000494:pharmacology*; D011957:Receptors, Opioid / Q000187:drug effects; D013329:Structure-Activity Relationship
D000701:Analgesics, Opioid; D000900:Anti-Bacterial Agents; D004044:Dietary Proteins; D010455:Peptides; D011957:Receptors, Opioid
Opiatopodobnaia i antimikrobnaia bioaktivnosti peptidov nekotorykh pishchevykh belkov.