title: [Dynamic MR mammography: is the course of signal intensification suitable for the differentiation of different forms of mastopathy?].
abstract: OBJECTIVE
  The capacity of dynamic contrast-enhanced MR mammography to distinguish between different forms and grades of mastopathy according to Prechtel's classification was evaluated in a retrospective study.
  
  
  METHODS
  MR mammograms of 51 patients with histologically proven mastopathy were retrospectively evaluated in areas subsequently biopsied.
  
  
  RESULTS
  Mean values of regressive and hyperplastic types of mastopathy differed significantly no significant differences were found between proliferating and non-proliferating mastopathies or Prechtel grades I-III mastopathy when MRI data obtained with a FLASH 3 D sequence (TR = 8.4 ms, TE = 3 ms, flip angle = 30 degrees at 1.0 T) were compared one minute, three, 5 and 8 minutes after i.v. bolus administration of contrast media (Gd-DTPA, 0.1 mmol/kg body weight).
  
  
  CONCLUSIONS
  Our data indicate that dynamic contrast-enhanced MR mammography does not allow the differentiation of proliferating and non-proliferating mastopathy according to the Prechtel classification. Dynamic MR mammography assessment of breast cancer risk does not seem to be feasible.
authors.affiliation: Institut für Radiologische Diagnostik, Klinikum Grosshadern, Ludwig-Maximilians-Universität, München.
authors.forename: H
authors.initials: H
authors.lastname: Sittek
authors.forename: M
authors.initials: M
authors.lastname: Kessler
authors.forename: A F
authors.initials: AF
authors.lastname: Heuck
authors.forename: A
authors.initials: A
authors.lastname: Lebeau
authors.forename: M
authors.initials: M
authors.lastname: Kohnert
authors.forename: M
authors.initials: M
authors.lastname: Untch
authors.forename: H
authors.initials: H
authors.lastname: Bohmert
authors.forename: M
authors.initials: M
authors.lastname: Reiser
mesh_terms: D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000145:classification / Q000175:diagnosis*; D001943:Breast Neoplasms / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D011446:Prospective Studies; D012189:Retrospective Studies; D018709:Statistics, Nonparametric
vernacular_title: Dynamische MR-Mammographie: Ist der Verlauf der Signalintensitätszunahme zur Differenzierung unterschiedlicher Formen der Mastopathie geeignet?