title: The relation between trabecular bone strength and bone mineral density assessed by dual photon and dual energy X-ray absorptiometry in the proximal tibia.
abstract: The feasibility of two noninvasive methods [dual photon absorptiometry (DPA) and dual energy X-ray absorptiometry (DXA)] for prediction in vivo of local variations of trabecular bone strength within the proximal tibia was evaluated in 14 cadaveric knees. Trabecular bone strength was measured using an osteopenetrometer and from destructive compression tests performed on bone cylinders, thus measuring the penetration strength and ultimate strength in the medial, lateral, and central part of the tibial bone specimens. Linear regression analysis showed significant relations between BMD measured by DPA (r2 = 72%) or DXA (r2 = 73%) and ultimate strength. Even closer relations between BMD (DPA: r2 = 80%, DXA r2 = 81%) and penetration strength of trabecular bone were found. We conclude that DPA and DXA are suitable methods for evaluation in vivo of local variations in trabecular bone strength within the proximal tibia, and could easily be performed preoperatively before insertion of total knee arthroplasty.
authors.affiliation: Department of Orthopaedic Surgery U, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, DK-2100 Copenhagen O, Denmark.
authors.forename: M M
authors.initials: MM
authors.lastname: Petersen
authors.forename: N C
authors.initials: NC
authors.lastname: Jensen
authors.forename: P M
authors.initials: PM
authors.lastname: Gehrchen
authors.forename: P K
authors.initials: PK
authors.lastname: Nielsen
authors.forename: P T
authors.initials: PT
authors.lastname: Nielsen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging / Q000502:physiology*