title: Adrenomedullin-immunoreactive neurons in the paraventricular and supraoptic nuclei of the rat.
abstract: The existence of adrenomedullin (AM) in the rat hypothalamus was examined by immunohistochemistry. AM-immunoreactive neurons were found in the supraoptic nucleus (SON) and in the magnocellular parts of the paraventricular nucleus (PVN). The co-existence of AM-, oxytocin- and/or vasopressin-immunoreactivity was identified in the same neurons in the hypothalamus. The results suggest that the AM may play a role in neurotransmission or in cardiovascular control with neurohypophyseal hormones.
authors.affiliation: Department of Physiology, University of Occupational and Environmental Health, Kitakyushu City, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Ueta
authors.forename: K
authors.initials: K
authors.lastname: Kitamura
authors.forename: T
authors.initials: T
authors.lastname: Isse
authors.forename: I
authors.initials: I
authors.lastname: Shibuya
authors.forename: N
authors.initials: N
authors.lastname: Kabashima
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
authors.forename: K
authors.initials: K
authors.lastname: Kangawa
authors.forename: H
authors.initials: H
authors.lastname: Matsuo
authors.forename: T
authors.initials: T
authors.lastname: Eto
authors.forename: H
authors.initials: H
authors.lastname: Yamashita
mesh_terms: D053607:Adrenomedullin; D000818:Animals; D000918:Antibody Specificity; D000959:Antihypertensive Agents / Q000032:analysis / Q000276:immunology*; D007150:Immunohistochemistry; D008297:Male; D010121:Oxytocin / Q000032:analysis; D010286:Paraventricular Hypothalamic Nucleus / Q000737:chemistry*; D010455:Peptides / Q000032:analysis / Q000276:immunology*; D051381:Rats; D017208:Rats, Wistar; D013495:Supraoptic Nucleus / Q000737:chemistry; D014667:Vasopressins / Q000032:analysis
chemical_list: D000959:Antihypertensive Agents; D010455:Peptides; D014667:Vasopressins; D053607:Adrenomedullin; D010121:Oxytocin