title: [D-Ala2,D-Leu5]-enkephalin hydrochloride.
abstract: The title compound, L-tyrosyl-D-alanyl-glycyl-L-phenyl-alanyl-D-leucine hydrochloride (C29H40N5O7+. Cl-), co-crystallizes with 2-butanone (C4H8O). The structure determination reveals a slightly distorted type I' beta-bend conformation stabilized by one intramolecular hydrogen bond. This conformation is similar to that observed for other [Leu]-enkephalin analogues.
authors.affiliation: Laboratory for the Structure of Matter, Naval Research Laboratory, Washington, DC 20375, USA. deschamps@lsm.nrl.navy.mil
authors.forename: J R
authors.initials: JR
authors.lastname: Deschamps
authors.forename: C
authors.initials: C
authors.lastname: George
authors.forename: J L
authors.initials: JL
authors.lastname: Flippen-Anderson
mesh_terms: D000595:Amino Acid Sequence; D002074:Butanones / Q000737:chemistry; D003460:Crystallization; D018360:Crystallography, X-Ray; D016308:Enkephalin, Leucine-2-Alanine / Q000737:chemistry*; D006860:Hydrogen Bonding; D008958:Models, Molecular; D008969:Molecular Sequence Data; D015394:Molecular Structure; D011487:Protein Conformation
chemical_list: D002074:Butanones; D016308:Enkephalin, Leucine-2-Alanine; C005222:methylethyl ketone