[New approaches to the pathogenetic therapy and prevention of acute kidney failure related to the use of x-ray contrast agents].
The authors analyze causes, mechanisms underlying acute renal failure (ARF) attributed to tests with application of radioopaque substances and results of ARF treatment in 12 ARF patients and on Wistar rats models. It is inferred that ARF is a frequent and severe complication of the above tests which may be treated successfully by early application of dialysis, filtration, sorption, plasmapheresis techniques. Disorders of calcium metabolism and their correction contribute to ARF onset. Radio-opaque substances have essential inhibiting action on nitrogen oxide synthesis in the kidneys of experimental animals.
Dzgoeva
F U
FU
Musselius
S G
SG
Kutyrina
I M
IM
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000517:prevention & control / Q000628:therapy*; D000328:Adult; D000368:Aged; D000818:Animals; D003131:Combined Modality Therapy; D003287:Contrast Media / Q000009:adverse effects*; D003974:Diatrizoate Meglumine / Q000009:adverse effects*; D004195:Disease Models, Animal; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009846:Oliguria / Q000139:chemically induced / Q000517:prevention & control / Q000628:therapy; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
D003287:Contrast Media; D003974:Diatrizoate Meglumine
Novye podkhody k patogeneticheskoĭ terapii i profilaktike ostroĭ pochechnoĭ nedostatochnosti, sviazannoĭ s primeneniem rentgenokontrastnykh sredstv.