title: Leiomyosarcoma with osteoclast-like giant cells of the spermatic cord. A case report and review of the literature.
abstract: We describe a case of leiomyosarcoma with osteoclast-like giant cells arising form the spermatic cord and involving the testis. This is a rare tumor which is histologically similar to the giant cell variant of malignant fibrous histiocytoma. No such cases have been reported arising from the external genitalia. The patient was initially treated with local excision. He had a local recurrence 7 years later which was treated with radical excision and adjuvant radiation. The indolent nature of the tumor, with a long survival of 7 years after initial diagnosis followed subsequently by a more aggressive clinical course, is emphasized.
authors.affiliation: Division of Urology, University of Pittsburgh School of Medicine, PA 15213, USA.
authors.forename: B R
authors.initials: BR
authors.lastname: Konety
authors.forename: J
authors.initials: J
authors.lastname: Singh
authors.forename: J C
authors.initials: JC
authors.lastname: Lyne
authors.forename: R R
authors.initials: RR
authors.lastname: Salup
mesh_terms: D000368:Aged; D005870:Giant Cell Tumors / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology* / Q000628:therapy; D008297:Male; D009364:Neoplasm Recurrence, Local; D010010:Osteoclasts / Q000473:pathology*; D013085:Spermatic Cord / Q000473:pathology*; D013736:Testicular Neoplasms / Q000473:pathology* / Q000628:therapy