title: Estrogen therapy in the management of problems associated with urogenital ageing: a simple diagnostic test and the effect of the route of hormone administration.
abstract: Estrogen deficient women are prone to problems such as vaginal dryness, dyspareunia and a predilection to recurrent urinary tract infections and urinary incontinence. A preliminary double-blinded study in 67 symptomatic postmenopausal women confirmed: (1) that atrophic vaginitis is associated with an increase in the lateral wall vaginal pH; (2) this is paralleled by similar changes in pH in the urethra; (3) locally applied vaginal conjugated estrogen cream normalizes the pH in the vagina and urethra. Thus, the testing of the vaginal pH serves both as a surrogate for evaluating urethral pH and as a monitor of compliance with treatment.
authors.affiliation: Women's Medical and Diagnostic Center, Gainesville, FL 32607, USA.
authors.forename: M
authors.initials: M
authors.lastname: Notelovitz
mesh_terms: D000375:Aging; D004311:Double-Blind Method; D015914:Estrogen Replacement Therapy; D004967:Estrogens / Q000008:administration & dosage*; D005260:Female; D052776:Female Urogenital Diseases / Q000628:therapy*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D017698:Postmenopause; D014622:Vaginal Creams, Foams, and Jellies
chemical_list: D004967:Estrogens; D014622:Vaginal Creams, Foams, and Jellies