title: Catecholamine secreting glomus tumor detected by iodine-123-MIBG scintigraphy.
abstract: We report the case of a 41-yr-old woman who presented with arterial hypertension and tinnitus in the right ear synchronous with pulse. She had previously undergone surgery for suspected pheochromocytoma without positive therapeutic effect. CT and MRI revealed a homogenous tumor with contrast enhancement in the right hypotympanon and foramen jugulare, and [123I]metaiodobenzylguanidine (MIBG) scintigraphy demonstrated strong tracer uptake in the same area. Selective venous sampling of catecholamines in the ipsilateral jugular vein confirmed the tumor to have originated from hormone production.
authors.affiliation: Department of Nuclear Medicine, University of Tübingen, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Reuland
authors.forename: D
authors.initials: D
authors.lastname: Overkamp
authors.forename: K P
authors.initials: KP
authors.lastname: Aicher
authors.forename: S
authors.initials: S
authors.lastname: Bien
authors.forename: W
authors.initials: W
authors.lastname: Müller-Schauenburg
authors.forename: U
authors.initials: U
authors.lastname: Feine
mesh_terms: D019797:3-Iodobenzylguanidine; D000310:Adrenal Gland Neoplasms / Q000175:diagnosis; D000328:Adult; D002395:Catecholamines / Q000378:metabolism*; D003287:Contrast Media; D004428:Ear Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000378:metabolism*; D004432:Ear, Middle; D005260:Female; D005918:Glomus Tumor / Q000150:complications / Q000000981:diagnostic imaging* / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D010673:Pheochromocytoma / Q000175:diagnosis; D014012:Tinnitus / Q000209:etiology; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D002395:Catecholamines; D003287:Contrast Media; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D019797:3-Iodobenzylguanidine