Pyralomicins, novel antibiotics from Microtetraspora spiralis. II. Structure determination.
Novel antibiotics, pyralomicins 1a approximately 1d, 2a approximately 2c were isolated from the culture broth of Microtetraspora spiralis MI178-34F18. The structures of pyralomicins were determined by various NMR spectral analyses including 1H-15N HMBC and 13C¿1H¿ NOE difference experiments.
Kawamura
N
N
Institute of Microbial Chemistry, Tokyo, Japan.
Sawa
R
R
Takahashi
Y
Y
Isshiki
K
K
Sawa
T
T
Naganawa
H
H
Takeuchi
T
T
D000192:Actinomycetales / Q000378:metabolism*; D000900:Anti-Bacterial Agents / Q000737:chemistry*; D002867:Chromones / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D011758:Pyrroles / Q000737:chemistry
D000900:Anti-Bacterial Agents; D002867:Chromones; D011758:Pyrroles; C101442:pyralomicin 1a