title: [Seroepidemiology for the hepatitis B virus (HBV) in pregnant women/parturients and its transmission to newborns in Goiânia, GO].
abstract: In order to detect hepatitis B virus (HBV), 1459 serum samples from pregnant/parturient women were collected at two public hospitals in Goiânia, GO. These samples were tested by enzyme linked immunosorbent assay for HBsAg and anti-HBs. 109 (7.5%) serum samples were positive. Eight (0.5%) sera were positive for HBsAg and 101 (7.0%) for anti-HBs. Viral positivity for both HBsAg and anti-HBs were observed in women which age ranged from 15 to 30 years. Four newborns from HBsAg positive mothers were submitted to the treatment with HBV vaccine (Engerix B) and with hyperimmune gammaglobulin (HBIG, Abbott Laboratories, Brazil). Cord blood from one of the newborns was positive for HBsAg. A positive association was found between hepatitis B and sexually transmitted infections and blood transfusion. These results emphasize the need for prenatal screening for HBV in pregnant women and treatment of the newborns from AgHBs-positive mothers.
authors.affiliation: Laboratório de Virologia, Departmento de Microbiologia, Instituto de Patologia Tropical e Saúde Pública, Universidade Federal de Goiás, Goiânia.
authors.forename: D
authors.initials: D
authors.lastname: Cardosa D das
authors.forename: E L
authors.initials: EL
authors.lastname: de Faria
authors.forename: M S
authors.initials: MS
authors.lastname: de Azevedo
authors.forename: D A
authors.initials: DA
authors.lastname: Queiroz
authors.forename: R M
authors.initials: RM
authors.lastname: Martins
authors.forename: T T
authors.initials: TT
authors.lastname: de Souza
authors.forename: R R
authors.initials: RR
authors.lastname: Daher
authors.forename: C M
authors.initials: CM
authors.lastname: Martelli
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D001938:Brazil / Q000453:epidemiology; D002648:Child; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission; D006510:Hepatitis B Antibodies / Q000097:blood*; D006511:Hepatitis B Antigens / Q000097:blood*; D006801:Humans; D007231:Infant, Newborn; D008875:Middle Aged; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology* / Q000276:immunology; D012307:Risk Factors; D016036:Seroepidemiologic Studies
chemical_list: D015415:Biomarkers; D006510:Hepatitis B Antibodies; D006511:Hepatitis B Antigens
vernacular_title: Soroepidemiologia para o vírus da hepatite B (VHB) em gestantes/parturientes e sua transmissão para recém-nascidos em Goiânia-GO.