An innate immune defense mechanism based on the recognition of CpG motifs in microbial DNA.
Krieg
A M
AM
Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA 52242, USA.
D000818:Animals; D015551:Autoimmunity / Q000502:physiology; D001402:B-Lymphocytes / Q000276:immunology; D018899:CpG Islands / Q000235:genetics*; D004269:DNA, Bacterial / Q000032:analysis* / Q000276:immunology; D015226:Dinucleoside Phosphates / Q000276:immunology / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D007113:Immunity, Innate / Q000235:genetics*; D007249:Inflammation / Q000276:immunology
D004269:DNA, Bacterial; D015226:Dinucleoside Phosphates; C015772:CpG dinucleotide