[Immune status and micro-hemodynamic function of patients with chronic alcoholism and liver pathology].
126 patients with chronic alcoholism combined with hepatic pathology (of alcoholic genesis) were examined. Laboratory immunological observations with the using of monoclonal antibodies demonstrated the expressed alterations of immune homeostasis exactly the decrease of total T-lymphocytes population (CD11+) as well as the number of T-helpers/inductors (CD40, immunoregulatory index and the increase of the level of circulating immune complexes. The correlation between the immune alterations and the microhemodynamic disturbances was also observed. In connection with the results mentioned above the question arose about application worth of both immunological correctors and angioprotectors in therapy of alcoholism espessially combined with hepatic pathology.
Kut'ko
I I
II
Frolov
V M
VM
Pustovoĭ
Iu G
IuG
Rachkauskas
G S
GS
D000328:Adult; D000917:Antibody Formation; D003228:Conjunctiva / Q000098:blood supply*; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007111:Immunity, Cellular; D008108:Liver Diseases, Alcoholic / Q000276:immunology* / Q000503:physiopathology*; D008111:Liver Function Tests; D008297:Male; D008833:Microcirculation / Q000503:physiopathology; D008875:Middle Aged; D013601:T-Lymphocytes / Q000276:immunology
Immunnyĭ status i sostianie mikrogemodinamiki bol'nykh khronicheskim alkogolizmom i patologieĭ pecheni.