title: [The gentic principles for the design of live Salmonella vaccines].
abstract: The presently known methods of obtaining Salmonella vaccine strains are characterized, their advantages and drawbacks are noted. Great importance of the genetic safety of Salmonella attenuated strains to be controlled is emphasized, taking into account that they are also used as carrier strains for obtaining hybrid and gene-engineering (vector) vaccines carrying immunogenicity factors of other species of pathogenic microorganisms.
authors.forename: V G
authors.initials: VG
authors.lastname: Petrovskaia
authors.forename: B I
authors.initials: BI
authors.lastname: Marakusha
authors.forename: V M
authors.initials: VM
authors.lastname: Bondarenko
mesh_terms: D001428:Bacterial Vaccines / Q000235:genetics* / Q000276:immunology; D015195:Drug Design; D005798:Genes, Bacterial / Q000235:genetics / Q000276:immunology; D009154:Mutation / Q000235:genetics / Q000276:immunology; D010957:Plasmids / Q000235:genetics / Q000276:immunology; D012269:Ribosomal Proteins / Q000235:genetics / Q000276:immunology; D012475:Salmonella / Q000235:genetics* / Q000276:immunology; D014613:Vaccines, Attenuated / Q000235:genetics / Q000276:immunology
chemical_list: D001428:Bacterial Vaccines; D012269:Ribosomal Proteins; D014613:Vaccines, Attenuated
vernacular_title: Geneticheskie printsipy konstruirovaniia zhivykh sal'monelleznykh vaktsin.