title: Imipramine: a model drug for P450 research.
authors.affiliation: Department of Clinical Pharmacology, Institute of Medical Biology, Odense University, Denmark.
authors.forename: K
authors.initials: K
authors.lastname: Brøsen
authors.forename: E
authors.initials: E
authors.lastname: Skjelbo
authors.forename: K K
authors.initials: KK
authors.lastname: Nielsen
mesh_terms: D000929:Antidepressive Agents, Tricyclic / Q000032:analysis / Q000378:metabolism* / Q000493:pharmacokinetics; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D019389:Cytochrome P-450 CYP2D6 / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D006801:Humans; D007099:Imipramine / Q000032:analysis / Q000378:metabolism* / Q000493:pharmacokinetics; D066298:In Vitro Techniques; D008862:Microsomes, Liver / Q000378:metabolism; D008954:Models, Biological; D009249:NADP / Q000378:metabolism
chemical_list: D000929:Antidepressive Agents, Tricyclic; D009249:NADP; D003577:Cytochrome P-450 Enzyme System; D019389:Cytochrome P-450 CYP2D6; D007099:Imipramine