title: Antipyrine, theophylline, and hexobarbital as in vivo P450 probe drugs.
authors.affiliation: Department of Clinical Pharmacokinetics, Janssen Research Foundation, Beerse, Belgium.
authors.forename: K
authors.initials: K
authors.lastname: Groen
authors.forename: D D
authors.initials: DD
authors.lastname: Breimer
mesh_terms: D000818:Animals; D000983:Antipyrine / Q000032:analysis / Q000378:metabolism* / Q000493:pharmacokinetics; D003577:Cytochrome P-450 Enzyme System / Q000032:analysis / Q000378:metabolism*; D006207:Half-Life; D006591:Hexobarbital / Q000032:analysis / Q000378:metabolism* / Q000493:pharmacokinetics; D006801:Humans; D015335:Molecular Probes; D051381:Rats; D013379:Substrate Specificity; D013806:Theophylline / Q000032:analysis / Q000378:metabolism* / Q000493:pharmacokinetics
chemical_list: D015335:Molecular Probes; D003577:Cytochrome P-450 Enzyme System; D006591:Hexobarbital; D013806:Theophylline; D000983:Antipyrine