Evaluation of haloperidol, a dopamine antagonist, on intraocular pressure in experimental glaucoma.
Haloperidol, a dopaminergic antagonist, was found to be very effective in lowering intraocular pressure in normal and glaucomatous eyes. The potential ocular hypotensive effect of haloperidol can be utilized for the treatment of glaucoma.
Khosla
P
P
Department of Pharmacology, Pt. B.D.Sharma P.G.I. of Medical Sciences, Rohtak, India.
Kothari
S
S
Gupta
M C
MC
Srivastava
R K
RK
D000818:Animals; D018492:Dopamine Antagonists / Q000494:pharmacology*; D005069:Evaluation Studies as Topic; D005260:Female; D005901:Glaucoma / Q000139:chemically induced / Q000188:drug therapy*; D006220:Haloperidol / Q000494:pharmacology*; D007429:Intraocular Pressure / Q000187:drug effects*; D008297:Male; D011817:Rabbits
D018492:Dopamine Antagonists; D006220:Haloperidol