title: [Therapeutic alternatives in the treatment of class T1N0 squamous cell carcinoma of the penis: indications and limitations].
abstract: At INT of Milan between 1964 and 1990, 204 consecutive native patients suffering from penile cancer have been treated. 101 (59%) patients out of 171 with invasive cancer (23 affected with Tis were excluded) have been classified T1N0M0. 74 patients have been treated with penis conserving methods, such as circumcision, radiotherapy, laser excision and primary chemotherapy + conserving surgery. Overall local failure and/or nodal relapses occurred in 27% (20/74). Relapses are significantly related with grading but there isn't any relationship with macroscopical aspect or size of the tumor. The conservative treatment had been possible in 80% of patients. In our experience T1N0 clinical stage conservative therapy does not worsen the prognosis.
authors.affiliation: Divisione di Urologia, Istituto per lo Studio e la Cura dei Tumori di Milano.
authors.forename: L
authors.initials: L
authors.lastname: Piva
authors.forename: N
authors.initials: N
authors.lastname: Nicolai
authors.forename: A
authors.initials: A
authors.lastname: Di Palo
authors.forename: A
authors.initials: A
authors.lastname: Milani
authors.forename: M
authors.initials: M
authors.lastname: Merson
authors.forename: R
authors.initials: R
authors.lastname: Salvioni
authors.forename: S
authors.initials: S
authors.lastname: Stagni
authors.forename: D
authors.initials: D
authors.lastname: Vecchio
authors.forename: F
authors.initials: F
authors.lastname: Zanoni
authors.forename: S
authors.initials: S
authors.lastname: Ferri
authors.forename: G
authors.initials: G
authors.lastname: Pizzocaro
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010412:Penile Neoplasms / Q000473:pathology / Q000628:therapy*
vernacular_title: Alternative terapeutiche nel trattamento del carcinoma spinocellulare del pene di categoria T1N0: indicazioni e limiti.