title: Performance assessment of a fuzzy controller for atracurium-induced neuromuscular block.
abstract: The performance of a fuzzy controller for atracurium-induced neuromuscular block was assessed. Ten ASA I or II patients undergoing surgery anticipated to last at least 120 min were studied. A Datex Relaxograph was used to monitor neuromuscular block. Initially the T1 set point was set at 10% of baseline for at least 30 min (phase I). The T1 set point was then increased to 20% and then returned to 10% for two further periods of at least 30 min duration (phases II and III). The mean (SD) of the mean T1 error in 10 patients for phases I, II and III were 1.1 (1.4)%, -0.43 (1.2)% and 0.28 (0.94)%, respectively. The results show that a simple fuzzy logic controller can provide good accuracy with insensitivity to set point changes despite the considerable inter-individual variation in infusion rate required.
authors.affiliation: Department of Automatic Control and Systems Engineering, University of Sheffield, South Yorkshire.
authors.forename: D G
authors.initials: DG
authors.lastname: Mason
authors.forename: N D
authors.initials: ND
authors.lastname: Edwards
authors.forename: D A
authors.initials: DA
authors.lastname: Linkens
authors.forename: C S
authors.initials: CS
authors.lastname: Reilly
mesh_terms: D000328:Adult; D000368:Aged; D001279:Atracurium; D004334:Drug Administration Schedule; D005260:Female; D017143:Fuzzy Logic; D006801:Humans; D007260:Infusion Pumps; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D009407:Nerve Block; D009469:Neuromuscular Junction / Q000187:drug effects*; D003473:Neuromuscular Nondepolarizing Agents
chemical_list: D003473:Neuromuscular Nondepolarizing Agents; D001279:Atracurium