Determination of bioconcentration factors of eight tetrachlorobenzyltoluenes in the zebra mussel Dreissena polymorpha.
Accurate duplicate bioconcentration factors were determined for tetrachlorobenzyltoluenes (TCBTs). This is the first study that quantifies bioconcentration factors for single TCBT isomers. A continuous flow uptake experiment was performed during 21 days with the zebra mussel (Dreissena polymorpha) as a test organism. Bioconcentration factors (BCFs) and rate constants were derived by an iterative integration method. With this method BCFs and rate constants can be derived from experimental data of a bio-concentration test, even if the concentration in the water is not constant and steady state has not been reached. Mean log BCF values of TCBTs ranged from 4.43 +/- 0.05 to 5.19 +/- 0.15 liter.kg-1 on a wet weight basis. The experimental log BCF values were compared with log BCF values of TCBTs, calculated according to linear and polynomial relationships between log BCF and log Kow.
van Haelst
A G
AG
Department of Environmental and Toxicological Chemistry, Amsterdam Research Institute for Substances in Ecosystems, University of Amsterdam, The Netherlands.
Zhao
Q
Q
van der Wielen
F W
FW
Govers
H A
HA
de Voogt
P
P
D000818:Animals; D001559:Benzhydryl Compounds / Q000378:metabolism / Q000633:toxicity*; D049872:Bivalvia / Q000378:metabolism*; D002849:Chromatography, Gas; D006843:Hydrocarbons, Chlorinated / Q000378:metabolism / Q000633:toxicity*; D007700:Kinetics; D011078:Polychlorinated Biphenyls / Q000032:analysis / Q000378:metabolism*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014874:Water Pollutants, Chemical / Q000032:analysis*
D001559:Benzhydryl Compounds; D006843:Hydrocarbons, Chlorinated; D014874:Water Pollutants, Chemical; D011078:Polychlorinated Biphenyls