Prevention of recurrent acute pancreatitis in patients with severe hypertriglyceridemia: value of regular plasmapheresis.
The association between acute pancreatitis and severe hypertriglyceridemia has long been recognized. We report two cases of severe primary hypertriglyceridemia (types 1 and V) with recurrent acute pancreatitis. In both patients, observance of appropriate diet and drug therapy was insufficient. Recurrent episodes of pancreatitis were precipitated by dietary fat or alcohol abuse. A plasmapheresis was performed every 4 weeks to decrease the incidence of pancreatitis. It appears that plasmapheresis is a safe and highly effective method for quickly removing serum triglycerides. Moreover, plasma-pheresis may be useful for preventing acute pancreatitis.
Piolot
A
A
Department of Internal Medicine and Nutrition, Henri Mondor Hospital, Créteil, France.
Nadler
F
F
Cavallero
E
E
Coquard
J L
JL
Jacotot
B
B
D000208:Acute Disease; D000328:Adult; D002784:Cholesterol / Q000097:blood; D005260:Female; D006801:Humans; D008072:Hyperlipoproteinemia Type I / Q000097:blood / Q000150:complications / Q000628:therapy; D006954:Hyperlipoproteinemia Type V / Q000097:blood / Q000150:complications / Q000628:therapy; D015228:Hypertriglyceridemia / Q000150:complications* / Q000628:therapy*; D008297:Male; D010195:Pancreatitis / Q000209:etiology / Q000517:prevention & control*; D010956:Plasmapheresis; D012008:Recurrence; D014280:Triglycerides / Q000097:blood
D014280:Triglycerides; D002784:Cholesterol