title: [Certain biochemical markers in women with abnormal states of the reproductive system].
abstract: The concentrations of collagen, hydroxyproline, glycosaminoglycans and estradiol were determined in 60 women aged 51 to 60 years (mean: 55.6 +/- 4.4). When compared with values from women with normal statics with women with lowered statics of the genital organ demonstrated significantly lower concentration of collagen (p < 0.05) in the teres ligaments. Women with prolapse of the genital organ had significantly lower concentration of estradiol in serum (p < 0.001) and of collagen (p < 0.01) in the teres ligaments, with significantly higher daily excretion of hydroxyproline (p < 0.01) and glycosaminoglycans (p < 0.001) in urine. In women with prolapse of the genital organ a significantly positive correlation between the concentration of estradiol and collagen (r = 0.76; p < 0.05) and negative correlation between the concentration of estradiol and hydroxyproline (r = -0.59; p < 0.05) and glycosaminoglycans (r = -0.61; p < 0.05) has been found.
authors.affiliation: Kliniki Ginekologii Instytutu Połoznictwa i Ginekologii PAM w Szczecinie.
authors.forename: S
authors.initials: S
authors.lastname: Stanosz
authors.forename: K
authors.initials: K
authors.lastname: Wilanowski
authors.forename: W
authors.initials: W
authors.lastname: Zebrowski
authors.forename: P
authors.initials: P
authors.lastname: Hajdasz
authors.forename: B
authors.initials: B
authors.lastname: Kościuszkiewicz
authors.forename: D
authors.initials: D
authors.lastname: Kuligowski
mesh_terms: D015415:Biomarkers / Q000032:analysis; D003094:Collagen / Q000032:analysis*; D004958:Estradiol / Q000032:analysis*; D005260:Female; D006025:Glycosaminoglycans / Q000032:analysis*; D006801:Humans; D006909:Hydroxyproline / Q000032:analysis*; D008875:Middle Aged; D014596:Uterine Prolapse / Q000175:diagnosis*
chemical_list: D015415:Biomarkers; D006025:Glycosaminoglycans; D004958:Estradiol; D003094:Collagen; D006909:Hydroxyproline
vernacular_title: Niektóre markery biochemiczne u kobiet z zaburzeniami statyki układu płciowego.