Cytomegalovirus as a cause of morbidity in heart transplantation. The experience of one center.
The accumulated data from 78 heart transplant recipients surviving for more than one month postoperatively were reviewed; the median duration of follow up was 16 months. Cytomegalovirus (CMV) disease was seen most frequently in recipients of hearts from CMV-seropositive donors, irrespective of the recipient CMV antibody status. CMV-related illness was detected in 13 patients; of the six who developed pneumonitis, five were CMV-seropositive recipients with seropositive donors. CMV was not a common cause of hepatitis or gastrointestinal symptoms.
Steel
H M
HM
Department of Medical Microbiology, St. George's Hospital Medical School, London, United Kingdom.
Murday
A J
AJ
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000150:complications*; D005260:Female; D016027:Heart Transplantation / Q000276:immunology*; D006525:Hepatitis, Viral, Human / Q000150:complications; D006566:Herpesviridae Infections / Q000150:complications; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D011024:Pneumonia, Viral / Q000150:complications; D014019:Tissue Donors
D000914:Antibodies, Viral