New genetics of mitochondrial DNA diseases.
Mitochondria have their own DNA which is maternally inherited. Mitochondrial DNA (mtDNA) diseases are extremely variable because of the genetics of mtDNA and the unique pathogenesis of these disorders. This makes predicting the prognosis and transmission of these disorders difficult.
Poulton
J
J
Department of Paediatrics, John Radeliffe Hospital, Oxford.
D004272:DNA, Mitochondrial / Q000235:genetics*; D015321:Gene Rearrangement / Q000235:genetics; D006801:Humans; D017240:Mitochondrial Myopathies / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D017354:Point Mutation / Q000235:genetics; D011296:Prenatal Diagnosis; D011379:Prognosis
D004272:DNA, Mitochondrial