Cloning of mouse prolidase cDNA: predominant expression of prolidase mRNA in kidney.
We cloned mouse prolidase cDNA from a mouse liver cDNA library. Homology to human prolidase is 83.2% at the nucleotide level and 87.2% at the amino acid level. Northern blot analysis showed that while prolidase mRNA was transcribed in brain, heart, liver, and muscle, it was predominantly transcribed in kidney.
Ishii
T
T
Department of Inherited Metabolic Diseases, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan.
Tsujino
S
S
Matsunobu
S
S
Endo
F
F
Sato
K
K
Sakuragawa
N
N
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics; D004150:Dipeptidases / Q000235:genetics*; D007668:Kidney / Q000737:chemistry* / Q000201:enzymology; D051379:Mice; D008969:Molecular Sequence Data; D012333:RNA, Messenger / Q000302:isolation & purification*; D017386:Sequence Homology, Amino Acid; D014018:Tissue Distribution
D018076:DNA, Complementary; D012333:RNA, Messenger; D004150:Dipeptidases; C022449:proline dipeptidase