Topical application of capsaicin and flap survival.
A study has been undertaken to investigate the relationship of capsaicin administration to flap survival. Skin flaps measuring 9 by 2 cm in size were raised on the dorsum of rats and covered with silicone gel sheet either containing or not containing capsaicin. Topical application of capsaicin transcutaneously resulted in a significant increase in the area of flap survival (P < 0.01).
Iinuma
T
T
Department of Plastic and Reconstructive Surgery, Hirosaki University School of Medicine, Japan.
Sawada
Y
Y
D000279:Administration, Cutaneous; D000818:Animals; D002211:Capsaicin / Q000008:administration & dosage*; D005260:Female; D006085:Graft Survival / Q000187:drug effects*; D015242:Ofloxacin / Q000008:administration & dosage; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage*; D051381:Rats; D011919:Rats, Inbred Strains; D016038:Skin Transplantation; D013524:Surgical Flaps
D010975:Platelet Aggregation Inhibitors; D015242:Ofloxacin; D002211:Capsaicin