title: Systemic lupus erythematosus valvulitis: mitral valve replacement with a homograft.
abstract: For many years, valvulitis in systemic lupus erythematosus has been known to occur. Our patient was a 17-year-old girl who presented with severe mitral incompetence and renal insufficiency due to lupus valvulitis. The patient was first treated by mitral valve repair, but follow-up disclosed precocious calcification of the valve, necessitating mitral valve replacement with a cryopreserved homograft. At follow-up after 1 year, echocardiography has shown the valve to be functioning normally. A reconstructive mitral valve operation would seem to be preferable. However, a conservative operation does not alter the natural history of the disease and the progression of valve thickening and calcification.
authors.affiliation: Department of Cardiovascular Surgery, Hôpital Broussais, Paris, France.
authors.forename: S M
authors.initials: SM
authors.lastname: Chauvaud
authors.forename: A
authors.initials: A
authors.lastname: Kalangos
authors.forename: A J
authors.initials: AJ
authors.lastname: Berrebi
authors.forename: A R
authors.initials: AR
authors.lastname: Gaer
authors.forename: C
authors.initials: C
authors.lastname: Acar
authors.forename: A F
authors.initials: AF
authors.lastname: Carpentier
mesh_terms: D000293:Adolescent; D002114:Calcinosis / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D005260:Female; D006349:Heart Valve Diseases / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D006801:Humans; D007249:Inflammation / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008943:Mitral Valve / Q000637:transplantation*; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000601:surgery; D014184:Transplantation, Homologous