title: Tamoxifen metabolism by microsomal cytochrome P450 and flavin-containing monooxygenase.
authors.affiliation: Worcester Foundation for Biomedical Research, Shrewsbury, Massachusetts 01545, USA.
authors.forename: D
authors.initials: D
authors.lastname: Kupfer
authors.forename: S S
authors.initials: SS
authors.lastname: Dehal
mesh_terms: D000818:Animals; D018931:Antineoplastic Agents, Hormonal / Q000032:analysis / Q000378:metabolism*; D002855:Chromatography, Thin Layer; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D004965:Estrogen Antagonists / Q000032:analysis / Q000378:metabolism*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008862:Microsomes, Liver / Q000201:enzymology; D010105:Oxygenases / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013629:Tamoxifen / Q000032:analysis / Q000378:metabolism*
chemical_list: D018931:Antineoplastic Agents, Hormonal; D004965:Estrogen Antagonists; D013629:Tamoxifen; D003577:Cytochrome P-450 Enzyme System; D010105:Oxygenases; C020066:dimethylaniline monooxygenase (N-oxide forming)