Current concepts of sepsis and acute lung injury.
Acute respiratory distress syndrome continues to be a vexing clinical problem with no specific therapy. Epidemiologic and basic sciences have advanced our understanding of the clinical syndrome and have brought us to the brink of effective intervention strategies. This article carefully examines the current state of knowledge, with reference to acute lung injury and current efforts, to arrive at effective pharmacologic approaches.
Sessler
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Department of Internal Medicine, Virginia Commonwealth University School of Medicine Medical College of Virginia, Richmond, USA.
Bloomfield
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GL
Fowler
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AA
D016207:Cytokines / Q000502:physiology; D006801:Humans; D007249:Inflammation / Q000628:therapy; D009102:Multiple Organ Failure; D015995:Prevalence; D012128:Respiratory Distress Syndrome / Q000453:epidemiology / Q000276:immunology* / Q000628:therapy; D018805:Sepsis / Q000453:epidemiology / Q000276:immunology*; D014057:Tomography, X-Ray Computed
D016207:Cytokines