A synthesis of the Amaryllidaceae alkaloid pratosine.
A synthesis of pratosine by thermolysis of the Michael adduct obtained from 5-hydroxy-8,9-dimethoxy-6(5H)-phenanthridone and methyl propiolate is described.
Pereira
M M
MM
Departmento de Química, SINTOR-UNINOVA, Monte da Caparica, Portugal.
Prabhakar
S
S
Lobo
A M
AM
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D007769:Lactams / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008970:Molecular Weight; D010936:Plant Extracts / Q000737:chemistry
D000470:Alkaloids; D007769:Lactams; D010936:Plant Extracts; C102970:pratosine