title: High complication rates with pelvic allografts. Experience of 22 sarcoma resections.
abstract: We performed 22 reconstructions by allografts in patients with pelvic sarcoma: 14 Ewing's sarcomas, 7 chondrosarcomas, and 1 osteosarcoma. All patients with Ewing's sarcoma and osteosarcoma received chemotherapy. No patients with chondrosarcoma had adjuvant treatment. 12 reconstructions were iliosacral arthrodesis after resection of an ilium tumor, 1 was iliofemoral arthrodesis and 9 were pelvic reconstructions with total hip prosthesis after resection of an acetabulum tumor. In the surviving patients, the mean length of follow-up was 4 (2-6) years. 2 allografts fractured and 8 allografts developed an infection. The infection was commoner in patients who had chondrosarcomas, large tumors, and a long operation time. Neither chemotherapy nor radiotherapy increased the infection rate. All infected allografts had to be removed.
authors.affiliation: Department of Orthopedics, Westfälische Wilhelms-University, Münster, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Ozaki
authors.forename: A
authors.initials: A
authors.lastname: Hillmann
authors.forename: D
authors.initials: D
authors.lastname: Bettin
authors.forename: P
authors.initials: P
authors.lastname: Wuisman
authors.forename: W
authors.initials: W
authors.lastname: Winkelmann
mesh_terms: D000293:Adolescent; D000328:Adult; D001174:Arthrodesis; D001859:Bone Neoplasms / Q000188:drug therapy / Q000601:surgery*; D016025:Bone Transplantation; D017024:Chemotherapy, Adjuvant; D002648:Child; D002813:Chondrosarcoma / Q000601:surgery*; D005260:Female; D050723:Fractures, Bone; D006801:Humans; D008297:Male; D008875:Middle Aged; D010384:Pelvic Bones / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology*; D012512:Sarcoma, Ewing / Q000188:drug therapy / Q000601:surgery*; D013530:Surgical Wound Infection / Q000601:surgery; D014184:Transplantation, Homologous; D016896:Treatment Outcome