title: Renal disease in an adult patient with type I glycogen storage disease.
abstract: A 26-year-old Chinese male patient with type I glycogen storage disease presented with chronic renal disease, proteinuria, and urolithiasis. On renal biopsy, focal glomerular sclerosis, increased mesangial matrix and cellularity, interstitial fibrosis, tubular atrophy, and prominent arteriosclerosis were observed. Immunofluorescence microscopy revealed Ig A deposits predominantly in the glomerular mesangium. The possible mechanisms of renal involvement in glycogen storage disease are briefly discussed.
authors.affiliation: Department of Internal Medicine, Kuang Tien General Hospital, Taichung, Taiwan, ROC.
authors.forename: P S
authors.initials: PS
authors.lastname: Lim
authors.forename: B
authors.initials: B
authors.lastname: Kho
mesh_terms: D000328:Adult; D017668:Age of Onset; D005953:Glycogen Storage Disease Type I / Q000150:complications* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000473:pathology; D008297:Male