title: Cloning and characterization of multiple opioid receptors.
abstract: Over the course of 1 to 2 years, the field has moved swiftly to investigate the functional and structural properties of the newly cloned opioid receptors. Achieving a better understanding of these macromolecules is likely to have profound implications for drug design aimed at the production of better analgesic drugs, for a more fundamental understanding of mechanisms of action of drugs of abuse, and for a more comprehensive knowledge base regarding the biology of opioid peptides in particular, and neuroactive peptides in general.
authors.affiliation: Mental Health Research Institute, University of Michigan, Ann Arbor 48109-0720, USA.
authors.forename: H
authors.initials: H
authors.lastname: Akil
authors.forename: F
authors.initials: F
authors.lastname: Meng
authors.forename: A
authors.initials: A
authors.lastname: Mansour
authors.forename: R
authors.initials: R
authors.lastname: Thompson
authors.forename: G X
authors.initials: GX
authors.lastname: Xie
authors.forename: S
authors.initials: S
authors.lastname: Watson
mesh_terms: D000818:Animals; D003001:Cloning, Molecular; D006801:Humans; D008024:Ligands; D010455:Peptides / Q000378:metabolism; D017465:Receptors, Opioid, delta / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D017473:Receptors, Opioid, kappa / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D017450:Receptors, Opioid, mu / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D011993:Recombinant Fusion Proteins / Q000737:chemistry / Q000502:physiology; D013329:Structure-Activity Relationship
chemical_list: D008024:Ligands; D010455:Peptides; D017465:Receptors, Opioid, delta; D017473:Receptors, Opioid, kappa; D017450:Receptors, Opioid, mu; D011993:Recombinant Fusion Proteins