title: Intravenous immunoglobulin replacement therapy for common variable immunodeficiency during pregnancy.
abstract: Patients with common variable immunodeficiency (CVID), characterized by impaired antibody production, have a high susceptibility to bacterial infections and need supplements of immunoglobulin G (IgG). We report two pregnancies in a woman with CVID. Differences in the outcome of the two pregnancies suggest the need for adjustment of replacement therapy during pregnancy.
authors.affiliation: Department of Obstetrics and Gynecology, Chiba University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Osada
authors.forename: Y
authors.initials: Y
authors.lastname: Morikawa
authors.forename: T
authors.initials: T
authors.lastname: Nishiwaki
authors.forename: S
authors.initials: S
authors.lastname: Sekiya
mesh_terms: D000328:Adult; D001991:Bronchitis / Q000276:immunology / Q000628:therapy; D017074:Common Variable Immunodeficiency / Q000276:immunology / Q000628:therapy*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use*; D007231:Infant, Newborn; D008297:Male; D009894:Opportunistic Infections / Q000276:immunology / Q000628:therapy*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology / Q000628:therapy*
chemical_list: D007074:Immunoglobulin G