Serotonin in violent patients with schizophrenia.
CSF levels of 5-hydroxyindolacetic acid (5-HIAA), the serotonin metabolite, were assayed in 10 violent and 10 matched nonviolent patients with schizophrenia. Mean group levels of 5-HIAA in cerebrospinal fluid were found to be nearly identical. Possible explanations, including effects of medications, are discussed.
Kunz
M
M
Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10965, USA.
Sikora
J
J
Krakowski
M
M
Convit
A
A
Cooper
T B
TB
Volavka
J
J
D000328:Adult; D001921:Brain / Q000503:physiopathology; D005260:Female; D006801:Humans; D006897:Hydroxyindoleacetic Acid / Q000134:cerebrospinal fluid; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000175:diagnosis / Q000503:physiopathology*; D012565:Schizophrenic Psychology; D012701:Serotonin / Q000502:physiology*; D014754:Violence / Q000523:psychology*
D012701:Serotonin; D006897:Hydroxyindoleacetic Acid