Evaluation of a survey of the diplomates of the American College of Laboratory Animal Medicine on use of analgesic agents in animals used in biomedical research.
OBJECTIVE
To determine the analgesic agents administered to animals frequently used in biomedical research.


METHODS
Telephone survey.


METHODS
Diplomates of the American College of Laboratory Animal Medicine.


METHODS
200 of 429 active diplomates listed in the 1993 directory of the American College of Laboratory Animal Medicine were selected at random for telephone interviews. Diplomates were asked to identify the species that they cared for and the dosages, dosing intervals, and routes of administration for analgesic agents.


RESULTS
90 of 200 (45%) diplomates completed the survey. Twenty-two analgesic agents were identified for use in 472 applications in 16 species. Opioid analgesics were the most frequently selected agents, with buprenorphine hydrochloride and butorphanol being most frequently used. Intramuscular and subcutaneous routes of administration were used most frequently.


CONCLUSIONS
Among diplomates of the American College of Laboratory Animal Medicine, opioids are the most frequently selected agents used to induce analgesia in animals used in biomedical research. Dosages and dosing intervals used vary widely among animals of various species as well as for animals in each species.
Hubbell
J A
JA
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus 43210-1089, USA.
Muir
W W
WW
D000700:Analgesics / Q000627:therapeutic use*; D000818:Animals; D002415:Cats; D006224:Cricetinae; D003625:Data Collection; D004285:Dogs; D004333:Drug Administration Routes; D004334:Drug Administration Schedule; D017723:Drug Utilization Review; D005289:Ferrets; D006041:Goats; D006168:Guinea Pigs; D011817:Rabbits; D012106:Research; D012756:Sheep; D013689:Telephone; D014481:United States; D014730:Veterinary Medicine / Q000592:standards*
D000700:Analgesics