title: [Prognostic factors of operated non-small-cell bronchogenic cancer: critical analysis of T.N.M].
abstract: A prospective study of prognosis factors for operated non-small-cell bronchogenic cancer was conducted to assess those proposed by the T.N.M. classification. From April 1984 to December 1993, 918 patients aged 32 to 83 years underwent surgery: 389 stage I; 367 stage II; 367 stage IIIa; and 25 stage IIIb. Macroscopic exeresis was satisfactory in all patients and node dissection of the mediastinum was performed. Post-operative mortality was 4%. Overall actuarial survival at 5 years was 43.9%, stage I 59.5%; stage II 53.8%; stage IIIa 25.1%; stage IIIb 29.3%. Tumor size, presence of visceral pleural invasion, and presence of local invasion (T3 and T4) worsened prognosis (concerning T). The prognosis value of N was the determining element: survival at 5 years, 56.3% for N0; 47.5% for N1 and 20% for N2. When metastases invaded two node chains in combinaison with T3, prognosis was poor. These cancers were stage IV.
authors.affiliation: Service de Chirurgie Thoracique, Hôpital Laennec, Paris.
authors.forename: M
authors.initials: M
authors.lastname: Riquet
authors.forename: D
authors.initials: D
authors.lastname: Manac'h
authors.forename: F
authors.initials: F
authors.lastname: Le Pimpec Barthes
authors.forename: R
authors.initials: R
authors.lastname: Souilamas
authors.forename: E
authors.initials: E
authors.lastname: Paris
authors.forename: A
authors.initials: A
authors.lastname: Dujon
authors.forename: B
authors.initials: B
authors.lastname: Debesse
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008168:Lung / Q000601:surgery; D008175:Lung Neoplasms / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009367:Neoplasm Staging; D011013:Pneumonectomy / Q000401:mortality; D011379:Prognosis; D011446:Prospective Studies
vernacular_title: Facteurs pronostiques du cancer bronchique non à petites cellules opéré: étude critique du T.N.M.