title: [False negative results by X scanners in intracranial tumors in adults].
abstract: We report a cohort of 34 cases, collected between 1978 and 1992, presenting with symptomatic intracranial tumours with a first negative CT scan. Subsequently, the tumours was revealed with a second CT scan or with an another neuroradiological technique (MRI or angiography). These "false negatives" represented 5% of all intracranial tumours seen during the same period of time in the same institution. Gliomas were observed in 67.7% of cases (a majority of them with a high grade). Initially, seizure was the most common clinical presentation (61.8%). Mean delay between the first scan and the definitive diagnosis was 13.4 months. The localization was supra-tentorial in 79.4% and infra-tentorial in 20.6%. This study leads us to discuss the attitude when a first CT scan is normal, more particularly in cases presenting with seizures, and the different factors that can explain the normality of this first CT scan.
authors.affiliation: Service de Neurologie, Hôpital Neurologique Pierre Wertheimer, Lyon.
authors.forename: P
authors.initials: P
authors.lastname: Petiot
authors.forename: P
authors.initials: P
authors.lastname: Herbin
authors.forename: A
authors.initials: A
authors.lastname: Vighetto
authors.forename: G
authors.initials: G
authors.lastname: Aimard
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology; D003951:Diagnostic Errors; D005188:False Negative Reactions; D005260:Female; D005910:Glioma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed
vernacular_title: Les faux négatifs du scanner X en pathologie tumorale intracrânienne de l'adulte.