title: Analysis of a 26 kb region on the left arm of yeast chromosome XV.
abstract: In the framework of the EC programme for sequencing yeast chromosome XV, we have determined the nucleotide sequence of a 26 kb region. Subsequent analysis revealed 13 non-overlapping open reading frames, three of which correspond to known yeast genes. A pair of tRNA genes associated with remnant Ty elements were localized in this region. From structural parameters and/or similarity searches with entries in the current data libraries, a preliminary functional assessment of several of the putative novel gene products can be made. The gene density in this region amounts to one gene in 2 kb. Protein coding regions occupy 61% of the total DNA sequence. Within the intergenic regions, potential regulatory elements can be predicted. The data obtained here may serve as a basis for a more detailed biochemical analysis of the novel genes. The complete nucleotide sequence of the 26 kb segment as depicted in Figure 1 has been deposited at the EBI data library under Accession Number X91067.
authors.affiliation: Institut für Physiologische Chemie, Physikalische Biochemie und Zellbiologie, Universität München, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Mannhaupt
authors.forename: I
authors.initials: I
authors.lastname: Vetter
authors.forename: C
authors.initials: C
authors.lastname: Schwarzlose
authors.forename: S
authors.initials: S
authors.lastname: Mitzel
authors.forename: H
authors.initials: H
authors.lastname: Feldmann
mesh_terms: D000595:Amino Acid Sequence; D001482:Base Composition; D002874:Chromosome Mapping; D015825:Chromosomes, Fungal / Q000235:genetics*; D004271:DNA, Fungal / Q000737:chemistry / Q000235:genetics; D005656:Fungal Proteins / Q000235:genetics; D005800:Genes, Fungal; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D017386:Sequence Homology, Amino Acid
chemical_list: D004271:DNA, Fungal; D005656:Fungal Proteins