title: Intracarotid blood pressure changes during contrast medium injection.
abstract: OBJECTIVE
  To investigate changes in blood pressure during intracarotid injection of contrast material.
  
  
  METHODS
  Two catheters were inserted into the ipsilateral common carotid artery of dogs. The proximal catheter was used for injection of contrast material and the other was positioned distally to monitor blood pressure.
  
  
  RESULTS
  Distal intracarotid pressure rose significantly during injection of contrast material at all rates (5, 7, and 10 mL/s) and at all doses (0.2, 0.5, 0.7, and 1.0 mL/kg). In addition, these blood pressure elevations were shown to be correlated with injection rates and doses. Even when the pressure-monitoring coaxial catheter was advanced into smaller arteries, no decline in the impact of injection was observed.
  
  
  CONCLUSIONS
  Intracarotid injection of contrast material causes a temporal elevation of cerebral blood pressure in dogs.
authors.affiliation: Department of Radiology, Kyoto City Hospital, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Saitoh
authors.forename: K
authors.initials: K
authors.lastname: Hayakawa
authors.forename: K
authors.initials: K
authors.lastname: Nishimura
authors.forename: Y
authors.initials: Y
authors.lastname: Okuno
authors.forename: C
authors.initials: C
authors.lastname: Murayama
authors.forename: T
authors.initials: T
authors.lastname: Miyazawa
authors.forename: B F
authors.initials: BF
authors.lastname: Zieroth
authors.forename: Y
authors.initials: Y
authors.lastname: Shimizu
mesh_terms: D000818:Animals; D001794:Blood Pressure / Q000187:drug effects*; D001921:Brain / Q000098:blood supply*; D002339:Carotid Arteries / Q000187:drug effects; D002533:Cerebral Angiography; D003287:Contrast Media / Q000494:pharmacology*; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D007269:Injections, Intra-Arterial; D007479:Iopamidol / Q000494:pharmacology*; D007485:Ioxaglic Acid / Q000494:pharmacology*
chemical_list: D003287:Contrast Media; D007479:Iopamidol; D007485:Ioxaglic Acid