[Disorders of neuromuscular transmission in patients with vibration-induced disease].
The author presents the data of electrophysiologic investigation of distal axon and synaptic structures in patients of different occupations (reveters, choppers, polishers) exposed to medium or high frequency vibration. A correlation analysis of SEMG index relation with the duration of service in confact with vibration showed it to cause two types of defects in neuromuscular transmission: myastenic and "increment" syndrome. The former correlated with vibratoin exposure, the letter--with duration of service. It was suggested to regard two types of synaptic disorders as a denervation reinnervation stage in axons terminals. Compensatory potential of axons is rather small, reinnervation capacities are short-termed and in spite of the absence of degenerative changes of axons advace. Mechanisms of traumatic effect of vibration on synaptic structures responsible for subsequent neuro-reflectory and neuro-trophyc changes of motor neuron of the spinal cord, were assertained according to SEMG, EMG and correlation analysis.
Liubimova
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D000328:Adult; D002908:Chronic Disease; D004576:Electromyography / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018763:Muscle Fatigue; D018908:Muscle Weakness / Q000209:etiology / Q000503:physiopathology; D009469:Neuromuscular Junction / Q000503:physiopathology*; D009784:Occupational Diseases / Q000209:etiology / Q000503:physiopathology*; D009435:Synaptic Transmission; D014732:Vibration / Q000009:adverse effects*
Narusheniia nervno-myshechnoĭ peredachi u bol'nykh vibratsionnoĭ bolezn'iu.