title: Local anaesthesia in flexible nasendoscopy. A comparison between cocaine and co-phenylcaine.
abstract: Flexible nasendoscopy is now an integral part of the diagnostic process in Otorhinolaryngology. Topical local anaesthesia is generally recommended and cocaine is usually the drug of choice in view of its concurrent vasoconstrictor action. However, it is expensive, a controlled drug and serious side effects have been reported. Co-phenylcaine forte is a new preparation which also has both local anaesthetic and vasoconstrictor properties. This study compares the efficacy of cocaine and Co-phenylcaine in flexible nasendoscopy and concludes that they provide similar local anaesthesia and vasoconstriction of the nasal mucosa. Co-phenylcaine forte can therefore be used as an alternative to cocaine in flexible nasendoscopy.
authors.affiliation: Department of Rhinology, Royal National Throat, Nose and Ear Hospital, London, UK.
authors.forename: P
authors.initials: P
authors.lastname: Lennox
authors.forename: J
authors.initials: J
authors.lastname: Hern
authors.forename: M
authors.initials: M
authors.lastname: Birchall
authors.forename: V
authors.initials: V
authors.lastname: Lund
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000772:Anesthesia, Local; D000779:Anesthetics, Local / Q000191:economics*; D003042:Cocaine / Q000191:economics; D003362:Cost-Benefit Analysis; D004338:Drug Combinations; D004724:Endoscopy; D006801:Humans; D008012:Lidocaine; D008875:Middle Aged; D009666:Nose / Q000473:pathology*; D009668:Nose Diseases / Q000473:pathology*; D010656:Phenylephrine; D014662:Vasoconstrictor Agents / Q000191:economics
chemical_list: D000779:Anesthetics, Local; D004338:Drug Combinations; D014662:Vasoconstrictor Agents; D010656:Phenylephrine; D008012:Lidocaine; D003042:Cocaine