title: Mechanical ventilation of newborns: experience from a level II NICU.
abstract: OBJECTIVE
  To analyse the indications, clinical profile, complications and outcome of the babies requiring mechanical ventilation.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  NICU of a teaching hospital.
  
  
  METHODS
  One hundred and twenty one neonates requiring assisted ventilation during three years.
  
  
  RESULTS
  Of 121 babies 59(48.76%) survived. Hyaline membrane disease (HMD) was the commonest indication for ventilation followed by birth asphyxia, apnea of prematurity, meconium aspiration syndrome (MAS) and septicemia. Infants with HMD whose birth weight was more than 1.5 kg and those who required ventilation after 24 hours of birth had better outcome. Survival rates increased with increasing birth weight and gestational age. Prolonged ventilatory support was needed for HMD (mean 117.3 hr) and MAS (mean 82.6 hr). Pneumonia was the commonest complication, followed by sepsis, air leak syndromes and intracranial and pulmonary hemorrhage.
  
  
  CONCLUSIONS
  Ventilatory facilities must be focussed for neonates weighing > 1000 g. Assisted ventilation may not be cost-effective in patients weighing < or = 1000 g and those with complex heart diseases and other congenital anomalies.
authors.affiliation: Department of Pediatrics, M.S. Ramaiah Medical College Hospital, Bangalore.
authors.forename: P P
authors.initials: PP
authors.lastname: Maiya
authors.forename: D
authors.initials: D
authors.lastname: Vishwanath
authors.forename: S
authors.initials: S
authors.lastname: Hegde
authors.forename: T P
authors.initials: TP
authors.lastname: Srinivas
authors.lastname: Shivaprasad
authors.forename: C C
authors.initials: CC
authors.lastname: Shantala
authors.forename: P
authors.initials: P
authors.lastname: Umakumaran
authors.forename: B
authors.initials: B
authors.lastname: Naveen
authors.forename: R K
authors.initials: RK
authors.lastname: Hegde
mesh_terms: D003362:Cost-Benefit Analysis; D006801:Humans; D015931:Intensive Care, Neonatal / Q000191:economics / Q000379:methods*; D012121:Respiration, Artificial / Q000009:adverse effects / Q000191:economics / Q000379:methods*; D012131:Respiratory Insufficiency / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome