[Disseminated aspergillosis and mucormycosis. A case report].
This paper reports a simultaneous pulmonary infection due to Aspergillus fumigatus and Rhizomucor pusillus which evolved to disseminated aspergillosis and mucormycosis in a leukaemic and neutropenic 40-year-old woman. Both fungi were cultured ante mortem from bronchial secretion. Although high doses of intravenous amphotericin B were administered, the course of the infection was fatal. At autopsy, aspergilli were demonstrated by histology in lungs and brain, and zygomycetes were found to have invaded liver and kidneys.
Mölle
M
M
Medizinische Klinik, Universitätsklinikum Carl Gustav Carus, Technischen Universität Dresden, Deutschland.
Blaschke-Hellmessen
R
R
Schuler
U
U
Nowak
R
R
Ehninger
G
G
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001228:Aspergillosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D001232:Aspergillus fumigatus / Q000254:growth & development / Q000302:isolation & purification; D001344:Autopsy; D002175:Candida / Q000302:isolation & purification; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications; D009090:Mucorales / Q000254:growth & development / Q000302:isolation & purification; D009091:Mucormycosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D009503:Neutropenia
D000935:Antifungal Agents; D000666:Amphotericin B
Disseminierte Aspergillose und Mucormykose. Ein Fallbericht.