Topoisomerase I-recognition-like sites in mycoplasma genomes.
Repeated nucleotide sequences fitting the motif TGTTTGAAAAACTGA have been found in the Mycoplasma bovis genome. The tetradecamer sequences are also in spacer regions of rRNA operons of some species of Mollicutes. The sequences look like the DNA sites recognized by topoisomerase I from Tetrahymena pyriformis. Imperfect copies of the sequences are known to be in genomes of viruses, lower and higher eukaryotes.
Chernov
V M
VM
Institute of Biology, Russian Academy of Sciences, Kazan, Russia.
Markina
O S
OS
Chernova
O A
OA
D000818:Animals; D001665:Binding Sites; D004264:DNA Topoisomerases, Type I / Q000378:metabolism*; D004269:DNA, Bacterial / Q000378:metabolism*; D009174:Mycoplasma / Q000235:genetics* / Q000378:metabolism; D012091:Repetitive Sequences, Nucleic Acid; D013379:Substrate Specificity
D004269:DNA, Bacterial; D004264:DNA Topoisomerases, Type I