title: Is increased voluntary motor activity beneficial or detrimental during the period of motor nerve regeneration/reinnervation?
abstract: A model of partial denervation of the rat lateral gastrocnemius was used to investigate the effects of daily activity (treadmill plus voluntary wheel exercise) on the regeneration/reinnervation of motoneurons recovering from nerve crush. It appears that increased activity has no effect on axon regeneration rate, but may be detrimental to the reinnervation process.
authors.affiliation: Département d'Education Physique, Université de Montréal, Succ. Centre-ville.
authors.forename: M
authors.initials: M
authors.lastname: Soucy
authors.forename: K
authors.initials: K
authors.lastname: Seburn
authors.forename: P
authors.initials: P
authors.lastname: Gardiner
mesh_terms: D000818:Animals; D001369:Axons / Q000502:physiology; D005260:Female; D009043:Motor Activity / Q000502:physiology*; D009046:Motor Neurons / Q000502:physiology*; D009119:Muscle Contraction; D018482:Muscle, Skeletal / Q000294:innervation*; D009416:Nerve Regeneration / Q000502:physiology*; D009434:Neural Pathways / Q000503:physiopathology; D009469:Neuromuscular Junction / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013126:Spinal Nerve Roots / Q000293:injuries / Q000503:physiopathology; D014945:Wound Healing