title: AV node reentry tachycardia in infants.
abstract: The purpose of this study was to determine the frequency of atrioventricular (AV) node reentry tachycardia in infants undergoing transesophageal electrophysiological study for paroxysmal tachycardia. The records of all 52 infants < 1-year-old with structurally normal hearts who underwent transesophageal study for paroxysmal tachycardia over a 3-year period were reviewed. Those with a diagnosis of AV node reentry tachycardia underwent complete data review, and follow-up of > 12 months was obtained. Six of 52 infants had a diagnosis of the common type of AV node reentry tachycardia. Tachycardia was diagnosed at a mean age of 2.1 months (range 1 day to 10 months), and 3 of 6 underwent transesophageal study within the first month. Although no patient had structural heart disease, three patients had significant noncardiac disease. Follow-up of 15-38 months (mean 24 +/- 7.8) revealed recurrences in 2 of 6 patients. The mean tachycardia cycle length was 240 ms (range 200-310 ms), and the transesophageal ventriculoatrial intervals ranged from < 30 to 55 ms. All patients had a inducible reentrant tachycardia with a ventriculoatrial interval that remained constant even when tachycardia cycle length increased following verapamil or adenosine administration, or decreased following isoproterenol infusion. Five of 6 had evidence for discontinuous AV node conduction curves. In our patients the substrate for AV node reentry tachycardia was present early in life, and AV node reentry tachycardia can be a clinical problem even in the newborn period.
authors.affiliation: Department of Pediatrics, University of Minnesota Hospital, Minneapolis, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Crosson
authors.forename: P S
authors.initials: PS
authors.lastname: Hesslein
authors.forename: O G
authors.initials: OG
authors.lastname: Thilenius
authors.forename: A
authors.initials: A
authors.lastname: Dunnigan
mesh_terms: D000241:Adenosine; D003937:Diagnosis, Differential; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007545:Isoproterenol; D008297:Male; D011446:Prospective Studies; D013611:Tachycardia, Atrioventricular Nodal Reentry / Q000151:congenital* / Q000175:diagnosis / Q000503:physiopathology; D013617:Tachycardia, Supraventricular / Q000151:congenital / Q000175:diagnosis / Q000503:physiopathology; D014700:Verapamil
chemical_list: D014700:Verapamil; D000241:Adenosine; D007545:Isoproterenol