title: Familial macrothrombocytopenia with unusually elongated mitochondria.
abstract: We report a familial case of macrothrombocytopenia without inclusion bodies in polymorphonuclear cells or any congenital abnormalities. The results of the hemostatic and platelet function tests were all normal except for the platelet retention rate. The number of megakaryocytes increased slightly and some were relatively small. Electron microscopic studies revealed a unique morphological abnormality of the platelets' mitochondria.
authors.affiliation: Department of Internal Medicine, Inazawa City Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Yamada
authors.forename: K
authors.initials: K
authors.lastname: Miwa
authors.forename: Y
authors.initials: Y
authors.lastname: Wakita
authors.forename: Y
authors.initials: Y
authors.lastname: Ikoma
authors.forename: Y
authors.initials: Y
authors.lastname: Fukui
authors.forename: M
authors.initials: M
authors.lastname: Okuyama
authors.forename: K
authors.initials: K
authors.lastname: Kato
authors.forename: T
authors.initials: T
authors.lastname: Ichihashi
authors.forename: S
authors.initials: S
authors.lastname: Kunishima
authors.forename: M
authors.initials: M
authors.lastname: Shamoto
mesh_terms: D000328:Adult; D001792:Blood Platelets / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D008928:Mitochondria / Q000648:ultrastructure*; D013921:Thrombocytopenia / Q000473:pathology*