Intravenous immunoglobulin replacement therapy for common variable immunodeficiency during pregnancy.
Patients with common variable immunodeficiency (CVID), characterized by impaired antibody production, have a high susceptibility to bacterial infections and need supplements of immunoglobulin G (IgG). We report two pregnancies in a woman with CVID. Differences in the outcome of the two pregnancies suggest the need for adjustment of replacement therapy during pregnancy.
Osada
H
H
Department of Obstetrics and Gynecology, Chiba University School of Medicine, Japan.
Morikawa
Y
Y
Nishiwaki
T
T
Sekiya
S
S
D000328:Adult; D001991:Bronchitis / Q000276:immunology / Q000628:therapy; D017074:Common Variable Immunodeficiency / Q000276:immunology / Q000628:therapy*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007074:Immunoglobulin G / Q000627:therapeutic use*; D007231:Infant, Newborn; D008297:Male; D009894:Opportunistic Infections / Q000276:immunology / Q000628:therapy*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000276:immunology / Q000628:therapy*
D007074:Immunoglobulin G