title: Recurrent ophthalmoplegia in childhood: diagnostic and etiologic considerations.
abstract: We present two patients with recurrent painful ophthalmoplegia starting in early childhood. Clinically, both patients fulfilled the criteria for ophthalmoplegic migraine. In one case, magnetic resonance investigations were performed following the second attack, between the third and fourth and during the fourth attack. The left third cranial nerve was significantly thickened in its course from the brainstem through the prepontine cistern to the cavernous sinus during the attacks and moderately thickened between the attacks. In the second case, magnetic resonance imaging was performed during the 14th attack, when the oculomotor nerve dysfunction was almost permanent, and the imaging demonstrated a swollen oculomotor nerve. Whether these findings are pathognomonic of ophthalmoplegic migraine awaits further reports using magnetic resonance imaging in infants showing recurrent painful ophthalmoplegia of early onset.
authors.affiliation: Department of Paediatrics, Arhus Kommunehospital, University Hospital of Aarhus, Denmark.
authors.forename: J R
authors.initials: JR
authors.lastname: Ostergaard
authors.forename: H U
authors.initials: HU
authors.lastname: Møller
authors.forename: T
authors.initials: T
authors.lastname: Christensen
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008881:Migraine Disorders / Q000473:pathology* / Q000503:physiopathology; D009886:Ophthalmoplegia / Q000473:pathology* / Q000503:physiopathology; D012008:Recurrence