[Pulmonary excisions in patients aged 75 and over. Study of postoperative mortality].
The aim of this study was to determine what factors beyond age affect post-operative mortality. We included 971 patients (mean age 61 +/- 10 years; 882 men, 89 women). There were 61 patients (6%) 75 years of age and over. Post-operative death rate was 15% in patients 75 and over versus 6% in patients under 75 (p = 0.01). Other variables significantly correlated with post-operative death after univariate analysis were: heart failure, Karnofsky score, VEMS, CV, PaCO2, tumor size, right side resection, pneumonectomy and large exeresis. Multivariate analysis retained 6 independent variables affecting post-operative mortality: age > or = 75 years (p = 0.019), Karnofsky score (p = 0.0001), right side resection (p = 0.0002, pneumonectomy (p = 0.04, large resection (p = 0.029) and hypocapnia (p = 0.01). If these parameters are considered when deciding on surgery, pulmonary exeresis may be proposed in elderly patients.
Bernard
A
A
Clinique Chirurgicale et Universitaire, Hôpital du Bocage, Dijon.
Benoit
L
L
Rat
P
P
Viard
H
H
Favre
J P
JP
D000368:Aged; D001984:Bronchial Neoplasms / Q000401:mortality / Q000503:physiopathology / Q000601:surgery; D005260:Female; D006801:Humans; D008168:Lung / Q000601:surgery; D008175:Lung Neoplasms / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D015999:Multivariate Analysis; D011013:Pneumonectomy / Q000401:mortality; D011184:Postoperative Period; D011379:Prognosis; D012129:Respiratory Function Tests; D012307:Risk Factors
Les exérèses pulmonaires chez les patients âgés de 75 ans et plus. Etude de la mortalité postopératoire.