title: [The efficacy and safety of glucosamine sulfate in the treatment of gonarthritis].
abstract: This study was performed to evaluate the therapeutic efficacy and tolerability of glucosamine sulfate in patients with gonarthritis. During the 12-month study period, the signs and symptoms of the disease were evaluated, as well as the dosage of the urinary pyridinoline. In this trial, we demonstrated that glucosamine sulfate has a chondroprotective activity, which was significant after the first 3 months of therapy. Moreover, this study showed that the side effects due to glucosamine sulfate were mild to moderate and did not require discontinuation of the drug.
authors.affiliation: Istituto di Patologia Speciale Medica, Università degli Studi di Siena.
authors.forename: N
authors.initials: N
authors.lastname: Giordano
authors.forename: P
authors.initials: P
authors.lastname: Nardi
authors.forename: M
authors.initials: M
authors.lastname: Senesi
authors.forename: F
authors.initials: F
authors.lastname: Palumbo
authors.forename: E
authors.initials: E
authors.lastname: Battisti
authors.forename: S
authors.initials: S
authors.lastname: Gonnelli
authors.forename: B
authors.initials: B
authors.lastname: Franci
authors.forename: M S
authors.initials: MS
authors.lastname: Campagna
authors.forename: C
authors.initials: C
authors.lastname: Gennari
mesh_terms: D000328:Adult; D000368:Aged; D000596:Amino Acids / Q000627:therapeutic use*; D000606:Amino Sugars / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004361:Drug Tolerance; D005260:Female; D005944:Glucosamine / Q000627:therapeutic use*; D006801:Humans; D008875:Middle Aged; D010003:Osteoarthritis / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D000596:Amino Acids; D000606:Amino Sugars; C015484:pyridinoline; D005944:Glucosamine
vernacular_title: Efficacia e tollerabilità della glucosamina solfato nel trattamento della gonartrosi.