title: Are engineered proteins getting competition from RNA?
abstract: Progress in several areas of research is pushing back the supposed limitations of nucleic acid structure and function. New ligand-binding and catalytic RNAs are being created at a rapid pace. Some engineered RNAs offer potential as therapeutic agents whereas others can be used as model systems to study the principles that direct structure formation, molecular recognition and catalytic function by nucleic acids.
authors.affiliation: Department of Biology, Yale University, New Haven, CT 06520, USA. ronald.breaker@yale.edu
authors.forename: R R
authors.initials: RR
authors.lastname: Breaker
mesh_terms: D001483:Base Sequence; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D015202:Protein Engineering; D012313:RNA / Q000737:chemistry* / Q000378:metabolism*; D016337:RNA, Catalytic / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D016601:RNA-Binding Proteins / Q000737:chemistry / Q000378:metabolism; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism
chemical_list: D016337:RNA, Catalytic; D016601:RNA-Binding Proteins; D011994:Recombinant Proteins; D012313:RNA