title: Magnetic field tomography of cortical and deep processes: examples of "real-time mapping" of averaged and single trial MEG signals.
abstract: Magnetic field tomography (MFT) provides 3-dimensional estimates of brain activity, from non-contact, non-invasive measurements of the magnetic field generated by coherent electrical activity in the brain. MFT analysis of averaged auditory "odd-ball" data show cortical and deep activation, presumably from the amygdala and hippocampus. These results are compared with MFT estimates obtained from a patient who had undergone lobectomy which removed these structures. The variability from subject to subject is confounded by variability between trials for the same subject; the relationship between the averaged and single trials is probed by bi-hemispheric simultaneous measurements performed under the same odd-ball paradigm and by MFT analysis of auditory evoked data and interictal epileptic activity.
authors.affiliation: Department of Physics, Open University, Milton Keynes, UK.
authors.forename: A A
authors.initials: AA
authors.lastname: Ioannides
authors.forename: M J
authors.initials: MJ
authors.lastname: Liu
authors.forename: L C
authors.initials: LC
authors.lastname: Liu
authors.forename: P D
authors.initials: PD
authors.lastname: Bamidis
authors.forename: E
authors.initials: E
authors.lastname: Hellstrand
authors.forename: K M
authors.initials: KM
authors.lastname: Stephan
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D001921:Brain / Q000502:physiology* / Q000503:physiopathology; D002540:Cerebral Cortex / Q000502:physiology* / Q000503:physiopathology; D003199:Computer Systems; D004827:Epilepsy / Q000503:physiopathology; D005072:Evoked Potentials, Auditory / Q000502:physiology; D006801:Humans; D015225:Magnetoencephalography / Q000295:instrumentation; D008297:Male; D014054:Tomography