Correlation between clinical response and injection quality in treatment of spasmodic dysphonia.
Botulinum toxin injection is an effective treatment for spasmodic dysphonia. There are ethical difficulties in performing a controlled placebo trial to assess the effectiveness of this treatment. This paper shows a significantly decreased clinical response following technically poor injections given to patients who respond well to good quality injections.
Tewary
A K
AK
Department of Otolaryngology, Queen Elizabeth Hospital, Birmingham, UK.
D001905:Botulinum Toxins / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D015552:Injections, Intralesional / Q000379:methods; D007830:Larynx / Q000187:drug effects*; D012008:Recurrence; D013997:Time Factors; D016896:Treatment Outcome; D014832:Voice Disorders / Q000188:drug therapy*
D001905:Botulinum Toxins