title: Mammalian artificial chromosomes.
abstract: The development of candidate vectors and of techniques for their manipulation by sequence targeting suggest that a mini-chromosome vector system for the mouse germline may be at hand. Mini-chromosome vectors should allow new sorts of genetic problems to be addressed experimentally and may accelerate the process of gene identification.
authors.affiliation: CRC Chromosome Molecular Biology Group, Biochemistry Department, Oxford University, UK. wrab@bioch.ox.sc.uk
authors.forename: W
authors.initials: W
authors.lastname: Brown
authors.forename: R
authors.initials: R
authors.lastname: Heller
authors.forename: M L
authors.initials: ML
authors.lastname: Loupart
authors.forename: M H
authors.initials: MH
authors.lastname: Shen
authors.forename: A
authors.initials: A
authors.lastname: Chand
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000166:cytology; D002460:Cell Line; D002645:Chickens; D002875:Chromosomes; D005822:Genetic Vectors; D006801:Humans; D008322:Mammals; D051379:Mice