Angiomyolipoma arising in the colon.
Extrarenal angiomyolipomas are very rare. Here we report the first case of surgically resected angiomyolipoma of the descending colon that developed in a 50-yr-old man. The patient had no signs of or family history of tuberous sclerosis. He underwent a partial colectomy because the tumor obstructed the colon. Histologically, the tumor consisted of three components: mature fat cells, blood vessels, and smooth muscle cells, and was thereby diagnosed as an angiomyolipoma. Immunohistochemically, the proliferating smooth muscle cells were positive for vimentin, alpha-smooth muscle actin, and desmin. The tumor cells were negative for HMB-45, which is consistently expressed in renal angiomyolipomas.
Maesawa
C
C
Department of Pathology, Iwate Medical University School of Medicine, Japan.
Tamura
G
G
Sawada
H
H
Kamioki
S
S
Nakajima
Y
Y
Satodate
R
R
D018207:Angiomyolipoma / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D003082:Colectomy; D003106:Colon / Q000473:pathology; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged