Developmental change in carotid artery blood flow waveform by component analysis in children.
The carotid artery blood flow waveform (CABFW) is regarded as a summation of cardiac impulse responses. These impulse responses are divided into several components through a two-dimensional autoregressive modelling approach. Using this approach, we determined the developmental change in CABFW in 94 normal subjects from the neonatal period to adolescence. Our analysis demonstrated that: (i) the total power of impulse response increased significantly with increasing age. The component of impulse response was divided into six groups according to the damping frequency: group I (0 Hz), group II (1-5 Hz), group III (5-8 Hz), group IV (8-13 Hz), group V (13-17 Hz) and group VI (> 17 Hz); (ii) the power-density and the damping time of group I and II impulse response increased significantly with increasing age; (iii) the power-density and percent power of group III impulse response and power-density of group IV impulse response increased significantly with increasing age. Our results indicated that CABFW contained some regular impulses and that group I, II, III and IV, which were influenced by several factors, including cardiac contraction and the compliance and frictional forces of the carotid artery, appeared to be important to the developmental change of CABFW in children.
Kojo
M
M
Department of Pediatrics, Oita Medical University, Japan.
Ogawa
T
T
Sonoda
H
H
Yamada
K
K
D000293:Adolescent; D002339:Carotid Arteries / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D006321:Heart / Q000502:physiology; D006801:Humans; D007223:Infant; D008954:Models, Biological; D012039:Regional Blood Flow; D012212:Rheology