title: [Use of an expandable metallic stent in patients with superior vena cava syndrome--comparison of angiographic findings and autopsy findings].
abstract: To evaluate the usefulness of expandable metallic stens (EMS) in patients with superior vena cava (SVC) syndrome, we compared venographic findings obtained before EMS insertion with findings at autopsy. Stents were inserted into the SVC in 10 patients. An autopsy was done in 7 of the 10 patients. At autopsy, the lumen of the SVC was patent in 4 patients; in those 4 patients venography before EMS insertion showed that the SVC was obstructed by extramural compression. These results suggest that extramural compression without direct invasion of the tumor is the best indication for insertion of an EMS. At autopsy, the lumen of the SVC was obstructed by direct invasion of a tumor in 2 patients; in those 2 patients venography showed wall irregularity and lumen narrowing caused by tumor invasion. However, in those 1 patients SVC syndrome either did not recur or recurred in only a mild form after EMS insertion. The results in these 2 patients suggest that if collateral circulation does not develop, insertion of an EMS is indicated also in patients in whom the SVC is obstructed by direct invasion of a tumor. In the remaining patient, the lumen of the SVC was found at autopsy to be obstructed by a thrombus. SVC syndrome developed in this patient 430 days after EMS insertion. In 1 of the 7 patients, an EMS was inserted into the left innominate vein and also into the SVC. Venography before EMS insertion showed that the vein was obstructed by extramural compression without direct invasion of the tumor, but the EMS was found at autopsy to be completely obstructed by a thrombus. This suggests that insertion of an EMS into the left innominate vein is not indicated this vein is easily obstructed by thrombi because of its anatomical location.
authors.affiliation: Department of Internal Medicine, Tokyo Saiseikai Central Hospital, Japan.
authors.forename: G
authors.initials: G
authors.lastname: Fuyuno
authors.forename: R
authors.initials: R
authors.lastname: Kobayashi
authors.forename: R
authors.initials: R
authors.lastname: Iga
authors.forename: H
authors.initials: H
authors.lastname: Nomori
authors.forename: H
authors.initials: H
authors.lastname: Horio
authors.forename: S
authors.initials: S
authors.lastname: Morinaga
authors.forename: K
authors.initials: K
authors.lastname: Kodera
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications; D008297:Male; D008875:Middle Aged; D011859:Radiography; D015607:Stents; D013479:Superior Vena Cava Syndrome / Q000473:pathology / Q000628:therapy*; D014683:Vena Cava, Superior / Q000000981:diagnostic imaging* / Q000473:pathology*