[Can monoclonal antibodies to a carcinoma-specific cell surface molecule prevent liver metastasis of human colorectal carcinoma and effectively treat already existing micrometastases?].
Burkart
C
C
Abt. Innere Medizin I, Eberhard-Karls-Universität Tübingen.
Porschen
R
R
D000230:Adenocarcinoma / Q000276:immunology / Q000556:secondary* / Q000628:therapy; D000818:Animals; D000911:Antibodies, Monoclonal / Q000276:immunology / Q000627:therapeutic use*; D000951:Antigens, Neoplasm / Q000276:immunology*; D000954:Antigens, Surface / Q000276:immunology*; D015179:Colorectal Neoplasms / Q000276:immunology / Q000628:therapy*; D003602:Cytotoxicity, Immunologic / Q000276:immunology; D000939:Epitopes / Q000276:immunology*; D006801:Humans; D008113:Liver Neoplasms / Q000276:immunology / Q000556:secondary* / Q000628:therapy; D051379:Mice; D008807:Mice, Inbred BALB C; D008819:Mice, Nude; D009368:Neoplasm Transplantation
D000911:Antibodies, Monoclonal; D000951:Antigens, Neoplasm; D000954:Antigens, Surface; D000939:Epitopes
Können monoklonale Antikörper gegen ein karzinomspezifisches Zelloberflächenmolekül die Lebermetastasierung humaner kolorektaler Karzinome verhindern und bereits bestehende Mikrometastasen beseitigen?