[Dynamic MR mammography: is the course of signal intensification suitable for the differentiation of different forms of mastopathy?].
OBJECTIVE
The capacity of dynamic contrast-enhanced MR mammography to distinguish between different forms and grades of mastopathy according to Prechtel's classification was evaluated in a retrospective study.


METHODS
MR mammograms of 51 patients with histologically proven mastopathy were retrospectively evaluated in areas subsequently biopsied.


RESULTS
Mean values of regressive and hyperplastic types of mastopathy differed significantly no significant differences were found between proliferating and non-proliferating mastopathies or Prechtel grades I-III mastopathy when MRI data obtained with a FLASH 3 D sequence (TR = 8.4 ms, TE = 3 ms, flip angle = 30 degrees at 1.0 T) were compared one minute, three, 5 and 8 minutes after i.v. bolus administration of contrast media (Gd-DTPA, 0.1 mmol/kg body weight).


CONCLUSIONS
Our data indicate that dynamic contrast-enhanced MR mammography does not allow the differentiation of proliferating and non-proliferating mastopathy according to the Prechtel classification. Dynamic MR mammography assessment of breast cancer risk does not seem to be feasible.
Sittek
H
H
Institut für Radiologische Diagnostik, Klinikum Grosshadern, Ludwig-Maximilians-Universität, München.
Kessler
M
M
Heuck
A F
AF
Lebeau
A
A
Kohnert
M
M
Untch
M
M
Bohmert
H
H
Reiser
M
M
D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000145:classification / Q000175:diagnosis*; D001943:Breast Neoplasms / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D011446:Prospective Studies; D012189:Retrospective Studies; D018709:Statistics, Nonparametric
Dynamische MR-Mammographie: Ist der Verlauf der Signalintensitätszunahme zur Differenzierung unterschiedlicher Formen der Mastopathie geeignet?