title: Dammarane-type triterpenoid saponins from Bacopa monniera.
abstract: Three new dammarane-type triterpenoid saponins, bacopasaponins A, B and C, of biological interest have been isolated from the reputed Indian medicinal plant Bacopa monniera and identified as 3-O-alpha-L-arabinopyranosyl-20-O-alpha-L-arabinopyranosyl-+ ++jujubogenin, 3-O-[alpha-L-arabinofuranosyl (1--> 2)alpha-L-arabinopyranosyl]pseudojujubogenin and 3-O-[beta-D-glucopyranosyl (1 -->3)[alpha-L-arabinofuranosyl (1--> 2)]alpha-L-arabinopyranosyl]pseudojujubogenin by spectroscopic methods and some chemical transformations. The hitherto undetermined configurations at C-20 and C-22 of pseudojujubogenin were elucidated by phase-sensitive ROESY, and 1H and 13C signals of the saponins were assigned by DEPT, 1H-1H COSY, HSQC and HMBC techniques.
authors.affiliation: Indian Institute of Chemical Biology, Calcutta, India.
authors.forename: S
authors.initials: S
authors.lastname: Garai
authors.forename: S B
authors.initials: SB
authors.lastname: Mahato
authors.forename: K
authors.initials: K
authors.lastname: Ohtani
authors.forename: K
authors.initials: K
authors.lastname: Yamasaki
mesh_terms: D002240:Carbohydrate Sequence; D007194:India; D009682:Magnetic Resonance Spectroscopy; D008519:Medicine, Traditional; D008969:Molecular Sequence Data; D015394:Molecular Structure; D010946:Plants, Medicinal; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013256:Steroids; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*; D000097669:Dammaranes
chemical_list: D012503:Saponins; D013256:Steroids; D014315:Triterpenes; D000097669:Dammaranes