title: [Longitudinal study on nasal polyposis: etiopathogenetic, clinical and therapeutic aspects].
abstract: The etiopathogenesis of nasal polyposis is yet uncertain; furthermore surgical treatment often is not able to completely resolve this problem, being recurrence very common. In our Clinic, we operated 647 patients for nasal polyposis, either by traditional surgical or endoscopy, in the last ten years. The aim of this study is to compare the results of different surgical techniques, considering the percentage of recurrence. We found that endoscopic surgery give better result than traditional one because it allows to see the place of origin of nasal polyps in the ethmoide. The follow-up was lasting between 1 and 10 years; during this time we administered a topical corticosteroide, to a group of patients, for 1 month; in a second group, we administered furosemide, a diuretic drug. According to our data, the percentage of recurrence in the group treated with furosemide was smaller than in other group treated with corticosteroide.
authors.affiliation: Istituto di Discipline Otorinolaringologiche, Università di Siena.
authors.forename: L
authors.initials: L
authors.lastname: Bellussi
authors.forename: G
authors.initials: G
authors.lastname: Marchi
authors.forename: M
authors.initials: M
authors.lastname: Lauriello
authors.forename: D
authors.initials: D
authors.lastname: Passàli
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002648:Child; D004232:Diuretics / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D005665:Furosemide / Q000627:therapeutic use; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009298:Nasal Polyps / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D012189:Retrospective Studies; D013256:Steroids
chemical_list: D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D004232:Diuretics; D013256:Steroids; D005665:Furosemide
vernacular_title: Studio longitudinale sui principali aspetti etiopatogenetici, clinici e terapeutici della poliposi nasale.