The cellulolytic system of Streptomyces reticuli.
The bacterium Streptomyces reticuli produces an unusual mycelia-associated cellulase (Avicelase, Cel1) which is solely sufficient to degrade crystalline cellulose to cellobiose. The enzyme consists of a binding domain, one adjoining region with unknown function, and a catalytic domain belonging to the cellulase family E. During cultivation, the strain produces a specific protease which processes the Avicelase to a truncated enzyme lacking the binding domain. The cellulase synthesis is regulated by induction (Avicel) and repression (metabolizable sugars and glycerol).
Schrempf
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FB Biologie/Chemie, Universitat Osnabrück, Germany.
Walter
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D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D001483:Base Sequence; D001665:Binding Sites; D002475:Cellobiose / Q000378:metabolism; D002480:Cellulase / Q000235:genetics / Q000378:metabolism*; D002482:Cellulose / Q000378:metabolism*; D043366:Cellulose 1,4-beta-Cellobiosidase; D010450:Endopeptidases / Q000378:metabolism; D004790:Enzyme Induction; D015964:Gene Expression Regulation, Bacterial; D015971:Gene Expression Regulation, Enzymologic; D005798:Genes, Bacterial; D008969:Molecular Sequence Data; D011499:Protein Processing, Post-Translational; D017386:Sequence Homology, Amino Acid; D013302:Streptomyces / Q000201:enzymology* / Q000235:genetics; D001617:beta-Glucosidase / Q000378:metabolism
D001426:Bacterial Proteins; D002475:Cellobiose; D002482:Cellulose; D001617:beta-Glucosidase; D002480:Cellulase; D043366:Cellulose 1,4-beta-Cellobiosidase; D010450:Endopeptidases