title: Circadian and circaannual oscillations of tissue lipoperoxides in rats.
abstract: Circadian and circaannual oscillations of tissue lipid peroxides (LPO) were studied in young male Wistar rats. The concentration of malondialdehyde, one of LPO degradation products, was measured at 3-h intervals during 24 hours in rats, adapted to light:dark 12:12 h regimen in the course of the year. LPO in the liver, thymus and bone marrow oscillated rhythmically in the course of the day and year. Circadian oscillations in all tissues were two-peaked, with zeniths at various times of the light and dark parts of the day. In the liver and thymus, the highest mesors were found during the winter, in the bone marrow during the spring. The same holds for amplitude values, with the exception of the bone marrow which exhibited the highest values during the summer. The reason for the LPO oscillations is probably resulting from the changing ratio of pro- and anti-oxidative capacities in various tissues during the day and the year.
authors.affiliation: Institute of Animal Physiology, Safárik University, Kosice, Slovak Republic.
authors.forename: P
authors.initials: P
authors.lastname: Solár
authors.forename: G
authors.initials: G
authors.lastname: Toth
authors.forename: B
authors.initials: B
authors.lastname: Smajda
authors.forename: I
authors.initials: I
authors.lastname: Ahlers
authors.forename: E
authors.initials: E
authors.lastname: Ahlersová
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000378:metabolism; D002940:Circadian Rhythm / Q000502:physiology*; D015227:Lipid Peroxidation / Q000502:physiology*; D008054:Lipid Peroxides / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D012621:Seasons; D013950:Thymus Gland / Q000378:metabolism
chemical_list: D008054:Lipid Peroxides; D008315:Malondialdehyde