title: [Evaluation of the synthesis and action of O- and N-aryl-piperazine propyl derivatives of ethyl ester acid 3-cyano-2-hydroxy-6-methylpyridine-4-carboxyl].
abstract: It was stated that alkylation of the sodium salt of ethyl 3-cyano-2-hydroxy-6-methylpyridine-4-carboxylate by arylpiperazynylpropyl chlorides gives the mixture of the corresponding O- and N-isomers. The compound 1 showed analgesic and anxiolytic activity.
authors.affiliation: Zakład Chemii Leków, Akademia Medyczna, Wrocław.
authors.forename: H
authors.initials: H
authors.lastname: Sladowska
mesh_terms: D000700:Analgesics / Q000138:chemical synthesis* / Q000737:chemistry; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000700:Analgesics; D011725:Pyridines
vernacular_title: Badania nad synteza i właściwościami O-i N-arylopiperazyny-lopropylowych pochodnych estru etylowego kwasu 3-cyja-no-2-hydroksy-6-metylopirydyno-4-karboksylowego.