title: Four Arabidopsis thaliana 14-3-3 protein isoforms can complement the lethal yeast bmh1 bmh2 double disruption.
abstract: The 14-3-3 proteins comprise a family of highly conserved proteins with multiple functions, most of which are related to signal transduction. Four isoforms from the plant Arabidopsis thaliana were able to complement the lethal disruption of the two Saccharomyces cerevisiae genes encoding 14-3-3 proteins; one complemented very poorly and one did not complement. However, the expression of the latter two isoforms was very low. These results show that at least four of the six A. thaliana isoforms are able to perform the same function(s) as the yeast 14-3-3 proteins.
authors.affiliation: Section Yeast Genetics, Institute of Molecular Plant Sciences, Leiden University, The Netherlands. Heusden@RULSFB.Leiden Univ.nl
authors.forename: G P
authors.initials: GP
authors.lastname: van Heusden
authors.forename: A L
authors.initials: AL
authors.lastname: van der Zanden
authors.forename: R J
authors.initials: RJ
authors.lastname: Ferl
authors.forename: H Y
authors.initials: HY
authors.lastname: Steensma
mesh_terms: D048948:14-3-3 Proteins; D017360:Arabidopsis / Q000235:genetics / Q000502:physiology*; D001483:Base Sequence; D015153:Blotting, Western; D018076:DNA, Complementary; D004271:DNA, Fungal; D005656:Fungal Proteins / Q000235:genetics / Q000502:physiology*; D005816:Genetic Complementation Test; D006801:Humans; D008969:Molecular Sequence Data; D011506:Proteins / Q000235:genetics / Q000502:physiology*; D029701:Saccharomyces cerevisiae Proteins; D014446:Tyrosine 3-Monooxygenase
chemical_list: D048948:14-3-3 Proteins; C075852:BMH1 protein, S cerevisiae; C097164:BMH2 protein, S cerevisiae; D018076:DNA, Complementary; D004271:DNA, Fungal; D005656:Fungal Proteins; D011506:Proteins; D029701:Saccharomyces cerevisiae Proteins; D014446:Tyrosine 3-Monooxygenase