[Examination of the toxicity of the liposomal form of amsacrine and retinoic acid].
The comparative toxicity studies of amsacrine and retinic acid administrated in solution and in liposome form were performed. The maximum survival time was longer for prepared liposome form than in the case of solution. The toxic effect was also lower for liposome preparations.
Tarasiuk
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Zakład Leków Witaminowych, Instytut Leków, Warszawa.
D000677:Amsacrine / Q000008:administration & dosage / Q000633:toxicity*; D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004337:Drug Carriers; D008081:Liposomes; D008297:Male; D051379:Mice; D015996:Survival Rate; D014212:Tretinoin / Q000008:administration & dosage / Q000633:toxicity*
D004337:Drug Carriers; D008081:Liposomes; D000677:Amsacrine; D014212:Tretinoin
Badanie toksyczności liposomalnej formy amsakryny i kwasu retynowego.