Inflammatory pseudotumour of the liver with malignant transformation. Report of two cases.
Inflammatory pseudotumour is a rare pathologic lesion, of unknown aetiology, rarely involving the liver. Resection seems to be the treatment of choice and it is generally associated with a good prognosis. Histologically, these processes appear to be benign, nevertheless, aggressive courses or recurrences of inflammatory pseudotumour with tumor-like deaths have been reported. The cases of two patients are described who underwent hepatic lobectomy for a liver mass that was diagnosed as liver inflammatory pseudotumour at the initial histopathological assessment: albeit a malignant course followed and both the patients died cachectic. One patient, a 39-year-old man, had an unusually aggressive clinical course and recurrence of the disease with multiple hepatic masses and extension into the thorax six years later. In the other case, in a 28-year-old woman, the hepatic lesion was identified as a low-grade hepatic sarcoma only seven years after surgery.
Zavaglia
C
C
Divisione di Medicina Generale Crespi, Ospedale Niguarda, Milano, Italy.
Barberis
M
M
Gelosa
F
F
Cimino
G
G
Minola
E
E
Mondazzi
L
L
Bottelli
R
R
Ideo
G
G
D000328:Adult; D002471:Cell Transformation, Neoplastic; D005260:Female; D006104:Granuloma, Plasma Cell / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology*; D008099:Liver / Q000473:pathology*; D008107:Liver Diseases / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D013997:Time Factors