title: Perioperative use of botulinum toxin for movement disorder-induced cervical spine disease.
abstract: Patients with cervical dystonia or tics of the nuchal muscles can develop serious cervical spine disease. We report a series of four patients who received botulinum toxin injections to control their movement disorders prior to their required surgery. One patient with cervical tic-induced radiculomyelopathy required botulinum toxin injection postoperatively to facilitate stabilization of the cervical fusion. Two patients with torticollis-induced cervical radiculomyelopathy, and one patient with dystonia-induced C5 fracture, had botulinum toxin injected preoperatively to facilitate postoperative recovery. Botulinum toxin appears to be a useful adjunct in the treatment of cervical movement disorders prior to or following surgery for associated cervical spine disease.
authors.affiliation: Department of Neurology, Mayo Clinic Scottsdale, Arizona 85259, USA.
authors.forename: C H
authors.initials: CH
authors.lastname: Adler
authors.forename: R S
authors.initials: RS
authors.lastname: Zimmerman
authors.forename: M K
authors.initials: MK
authors.lastname: Lyons
authors.forename: F
authors.initials: F
authors.lastname: Simeone
authors.forename: M F
authors.initials: MF
authors.lastname: Brin
mesh_terms: D000328:Adult; D001905:Botulinum Toxins / Q000008:administration & dosage*; D002574:Cervical Vertebrae / Q000601:surgery*; D004421:Dystonia / Q000601:surgery*; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009334:Neck Muscles / Q000601:surgery*; D011292:Premedication; D013117:Spinal Cord Compression / Q000601:surgery; D013122:Spinal Diseases / Q000601:surgery*; D013123:Spinal Fusion; D013130:Spinal Stenosis / Q000601:surgery; D013167:Spondylitis, Ankylosing / Q000601:surgery; D014103:Torticollis / Q000601:surgery*; D005879:Tourette Syndrome / Q000601:surgery
chemical_list: D001905:Botulinum Toxins