Radiation-induced urothelial carcinoma.
Four cases of urothelial carcinoma following pelvic irradiation for carcinomas of the cervix uteri (n = 3) and the ovary (n = 1) are reported. The urothelial carcinomas developed 26.8 (mean) years after radiotherapy and invaded the bladder in 3 patients and the ureter in 1. Despite radical surgery, the patients died of metastatic cancer.
Saito
M
M
Department of Urology, Nagoya University School of Medicine, Japan.
Kondo
A
A
Kato
T
T
Kobayashi
M
M
Miyake
K
K
D000328:Adult; D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000209:etiology* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D010051:Ovarian Neoplasms / Q000532:radiotherapy*; D011878:Radiotherapy / Q000009:adverse effects; D014516:Ureteral Neoplasms / Q000209:etiology* / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000209:etiology* / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000532:radiotherapy*