Genetic variability in resistance of Creole goats to natural infection with trichostrongylids in Guadeloupe.
The objective of this study was to show the existence of genetic variability in resistance of Creole goats to natural infection with intestinal nematodes. Four successive cohorts of male and female kids were reared from weaning during 9 months in intensive pangola pastures (stocking rate 1.4 t/ha, regrowth of 21 days, 300 kg N/ ha/year of fertilization). All cohorts considered, 203 offsprings from 13 bucks and 149 goats were used in the experiment. Animals were treated with an oral dose of ivermectin every seven weeks, from 3 to 11 months of age. They were sampled for fecal egg counts (FEC) and packed cell volume (PCV), 6 weeks after drenching, when 6 and 10 months old. Haemonchus contortus and Trichostrongylus colubriformis were the predominant species. Data of one cohort when 6 months of age and another one when 10 months old were not included in calculations because a self-cure occurred during a rainy season. Estimated means of FEC after square-root transformation were 1054 and 711 respectively for 6-month-old and 10-month-old kids. Phenotypic correlations between FEC and PCV were -0.46 (p < 0.001) and -0.29 (p < 0.01) when 6 and 10 months old, respectively. FEC repeatabilities estimated as variance ratio were 0.47 and 0.06 for within-age measures (data recorded at one week interval) and between age measures (6 vs. 10 months) respectively. No sire effect was significant for PCV. Sire effect on FEC was more significant when 6 months old (p < 0.03) than when 10 months old (p < 0.15). Further studies are now being carried out to confirm this genetic determinism of resistance to natural infection with strongyles in Creole goats.
Mandonnet
N
N
INRA Station de Pathologie Aviarie et de Parasitologie, Nouzilly, France.
Aumont
G
G
Fleury
J
J
Gruner
L
L
Bouix
J
J
Khang
J V
JV
D000375:Aging; D000818:Animals; D015331:Cohort Studies; D005260:Female; D015511:Goat Diseases; D006041:Goats / Q000235:genetics* / Q000276:immunology*; D007113:Immunity, Innate / Q000235:genetics; D008297:Male; D010270:Parasite Egg Count; D010641:Phenotype; D012621:Seasons; D012727:Sex Characteristics; D014251:Trichostrongyloidea / Q000302:isolation & purification; D014252:Trichostrongyloidiasis / Q000276:immunology / Q000662:veterinary*; D015430:Weight Gain; D014900:West Indies