Imipramine: a model drug for P450 research.
Brøsen
K
K
Department of Clinical Pharmacology, Institute of Medical Biology, Odense University, Denmark.
Skjelbo
E
E
Nielsen
K K
KK
D000929:Antidepressive Agents, Tricyclic / Q000032:analysis / Q000378:metabolism* / Q000493:pharmacokinetics; D001711:Biotransformation; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D019389:Cytochrome P-450 CYP2D6 / Q000378:metabolism; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D006801:Humans; D007099:Imipramine / Q000032:analysis / Q000378:metabolism* / Q000493:pharmacokinetics; D066298:In Vitro Techniques; D008862:Microsomes, Liver / Q000378:metabolism; D008954:Models, Biological; D009249:NADP / Q000378:metabolism
D000929:Antidepressive Agents, Tricyclic; D009249:NADP; D003577:Cytochrome P-450 Enzyme System; D019389:Cytochrome P-450 CYP2D6; D007099:Imipramine