HIV: dendritic cells as embers for the infectious fire.
In people with HIV-1, most of the CD4-expressing T cells that produce virus are short-lived and vulnerable to anti-retroviral agents. But the initial 'fire' of HIV-1 infection may begin in, and be maintained by, cells of the dendritic cell lineage.
Clark
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Department of Microbiology and Regional Primate Research Center, University of Washington, Seattle 98195, USA.
D000818:Animals; D003713:Dendritic Cells / Q000502:physiology* / Q000821:virology; D015497:HIV-1 / Q000502:physiology*; D006801:Humans; D014779:Virus Replication