title: Gastric lymphoma in Grampian Region: presentation, treatment and outcome.
abstract: Forty cases of gastric lymphoma presenting in Grampian Region (1974-91) were reviewed to examine the effects of changing ideas in the fields of chemotherapy, gastric surgery and diagnostic techniques, as well as the impact of Helicobacter pylori. Presentation was non-specific, and the diagnosis was made pre-operatively in only 12 cases. Survival was related to tumour size, staging (Ann Arbor), and grade, with a crude 5-year survival of 49%. Helicobacter pylori was found in all specimens reviewed. Patients who underwent "potentially curative' surgery followed by adjuvant therapy had the best survival (85% at 5 years). There remains a need for larger studies to define the best treatment for this uncommon condition.
authors.affiliation: Department of Surgery, Aberdeen Royal Infirmary, Foresterhill, UK.
authors.forename: A G
authors.initials: AG
authors.lastname: Sutherland
authors.forename: M
authors.initials: M
authors.lastname: Kennedy
authors.forename: D N
authors.initials: DN
authors.lastname: Anderson
authors.forename: K G
authors.initials: KG
authors.lastname: Park
authors.forename: R A
authors.initials: RA
authors.lastname: Keenan
authors.forename: A I
authors.initials: AI
authors.lastname: Davidson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D016481:Helicobacter Infections / Q000150:complications; D016480:Helicobacter pylori; D006801:Humans; D015993:Life Tables; D008223:Lymphoma / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012606:Scotland; D013274:Stomach Neoplasms / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D015996:Survival Rate; D016896:Treatment Outcome