[Mutational analysis and genetic cloning of the agnostic locus controlling learning ability in Drosophila].
The ts-mutations of the agnostic gene either increased or decreased the activity of the AC and PDE. A chromosomal deficiency in the 11B region failed to complement with the agnostic behavioral defect like agn P29 and P40, led to an increased proportion of the PDE-1 in total PDE and to the structural defects in the central complex thus indicating that the P insertion is responsible for the mutant agnostic phenotype.
Peresleni
A I
AI
Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg.
Savvateeva
E V
EV
Peresleni
I V
IV
Sharagina
L M
LM
D000818:Animals; D003001:Cloning, Molecular / Q000379:methods; D000242:Cyclic AMP / Q000378:metabolism; D004252:DNA Mutational Analysis; D004251:DNA Transposable Elements / Q000235:genetics / Q000502:physiology; D004331:Drosophila melanogaster; D005260:Female; D005796:Genes / Q000235:genetics* / Q000502:physiology; D005824:Genetics, Behavioral; D006579:Heterozygote; D007858:Learning / Q000502:physiology*; D008297:Male; D009154:Mutation / Q000235:genetics / Q000502:physiology; D010641:Phenotype; D010727:Phosphoric Diester Hydrolases / Q000378:metabolism; D014960:X Chromosome / Q000235:genetics / Q000502:physiology
D004251:DNA Transposable Elements; D000242:Cyclic AMP; D010727:Phosphoric Diester Hydrolases
Mutatsionnyĭ analiz i geneticheskoe klonirovanie lokusa agnostic, kontroliruiuschego sposobnost'k obucheniiu, u drozofily.