title: [Effect of elevated head position in bed in therapy of gastroesophageal reflux].
abstract: In a randomized multicentric trial the effect of sleeping with the bed-head raised was studied in inpatients with reflux symptoms. All patients underwent an endoscopic and pH-metric examination. As a result from the diagnostic procedures three groups were formed: group 1 - refluxlike dyspepsia (endoscopic and pH-metric examination normal), group 2 - reflux disease without esophagitis (endoscopy normal, pH-metric examination abnormal), group 3 - refluxesophagitis (endoscopy abnormal). All patients were randomly assigned to either sleeping with horizontal bed-head or having the bed-head raised (15 cm). Furthermore, the patients in group 3 were put on treatment with omeprazole (20 mg twice a day) those in group 2 were treated with a procinetic drug (cisapride 30 mg). The patients in group 1 had no drug therapy. However, antacids were allowed in all patients. For a two-week-period reflux symptoms and use of antacids were registered. No difference was seen in the symptom-score or use of antacids. Also sub-group analysis (sex, age, body-mass-index, severity of esophagitis and nocturnal reflux) did not reveal any impact of sleeping with the bed-head raised on reflux symptoms or use of antacids.
authors.affiliation: Klinik Niederrhein, LVA Rheinprovinz Bad Neuenahr.
authors.forename: H
authors.initials: H
authors.lastname: Pollmann
authors.forename: E
authors.initials: E
authors.lastname: Zillessen
authors.forename: J
authors.initials: J
authors.lastname: Pohl
authors.forename: D
authors.initials: D
authors.lastname: Rosemeyer
authors.forename: A
authors.initials: A
authors.lastname: Abucar
authors.forename: U
authors.initials: U
authors.lastname: Armbrecht
authors.forename: B
authors.initials: B
authors.lastname: Bornhofen
authors.forename: R
authors.initials: R
authors.lastname: Herz
mesh_terms: D000328:Adult; D000863:Antacids / Q000008:administration & dosage; D000897:Anti-Ulcer Agents / Q000008:administration & dosage; D020117:Cisapride; D003131:Combined Modality Therapy; D004942:Esophagitis, Peptic / Q000534:rehabilitation*; D005260:Female; D005745:Gastric Acidity Determination; D005764:Gastroesophageal Reflux / Q000534:rehabilitation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009853:Omeprazole / Q000008:administration & dosage; D010880:Piperidines / Q000008:administration & dosage; D011187:Posture; D011446:Prospective Studies; D016896:Treatment Outcome
chemical_list: D000863:Antacids; D000897:Anti-Ulcer Agents; D010880:Piperidines; D009853:Omeprazole; D020117:Cisapride
vernacular_title: Effekt der kopferhöhten Bettlage in der Therapie der gastroösophagealen Refluxkrankheit.