Cell damage after shock.
Hypoperfusion of tissue results in cell membrane dysfunction. Normally, the cell membrane serves to preserve the milieu interior through the maintenance of a negative charge or membrane potential. Maintenance of a negative membrane potential across the cell membrane serves as a semipermeable barrier, preserving the balance of intra- and extracellular electrolytes and water.
Barber
A E
AE
Department of Surgery, Texas Tech University Health Sciences Center, Lubbock, USA.
Shires
G T
GT
D000818:Animals; D002056:Burns / Q000503:physiopathology; D002462:Cell Membrane / Q000502:physiology; D004573:Electrolytes / Q000378:metabolism; D006801:Humans; D018836:Inflammation Mediators / Q000502:physiology; D008564:Membrane Potentials; D018482:Muscle, Skeletal / Q000378:metabolism / Q000503:physiopathology; D012769:Shock / Q000503:physiopathology*; D012771:Shock, Hemorrhagic / Q000503:physiopathology; D012772:Shock, Septic / Q000503:physiopathology; D012774:Shock, Traumatic / Q000503:physiopathology
D004573:Electrolytes; D018836:Inflammation Mediators