title: Utility of technetium-99m-sestamibi to assess osseous tumor spread.
abstract: We report the staging results and the surgical outcome of a male patient with squamous-cell carcinoma in the floor of the mouth and a bone SPECT scan suggestive of local tumor infiltration of the mandible. Additional 99mTc-sestamibi SPECT imaging of the primary tumor and superimposing of both studies excluded osseous tumor spread and less extensive surgery was performed. Pathohistological examination confirmed the scintigraphic results and indicated a nonspecific periostal reaction as the cause of the positive bone scan. Nevertheless, a high-resolution camera and careful superimposition of both studies is mandatory if the differential diagnosis of an osseous tumor spread of a malignant tumor in the floor of the mouth and possibly less extensive surgery is at stake.
authors.affiliation: University Clinic of Maxillofacial Surgery, Vienna, Austria.
authors.forename: C
authors.initials: C
authors.lastname: Glaser
authors.forename: M
authors.initials: M
authors.lastname: Pruckmayer
authors.forename: A
authors.initials: A
authors.lastname: Staudenherz
authors.forename: M
authors.initials: M
authors.lastname: Rasse
authors.forename: S
authors.initials: S
authors.lastname: Lang
authors.forename: T
authors.initials: T
authors.lastname: Leitha
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000473:pathology; D004164:Diphosphonates; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D009060:Mouth Floor; D009062:Mouth Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D009361:Neoplasm Invasiveness; D015609:Organotechnetium Compounds; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D004164:Diphosphonates; D015609:Organotechnetium Compounds; C033905:technetium Tc 99m 1,1-diphosphonopropane-2,3-dicarboxylic acid; D017256:Technetium Tc 99m Sestamibi