[Organization of the gene for the beta-subunit of human photoreceptor cyclic GMP phosphodiesterase].
Two recombinant bacteriophage lambda clones encoding a 27.8-kb fragment of the human phosphodiesterase beta-subunit gene were isolated from a human genomic library. The nucleotide sequences of 19 exons (from the 4th to 22nd), 18 introns, and the 3'-flanking region were determined. The analysis of the nucleotide sequence of the phosphodiesterase beta-subunit gene revealed four Alu repeats and four minisatellite regions.
Suslova
V A
VA
Suslov
O N
ON
Kim
E E
EE
Lipkin
V M
VM
D015106:3',5'-Cyclic-GMP Phosphodiesterases / Q000235:genetics*; D000595:Amino Acid Sequence; D010582:Bacteriophage lambda / Q000235:genetics; D001483:Base Sequence; D003001:Cloning, Molecular; D054707:Cyclic Nucleotide Phosphodiesterases, Type 6; D018076:DNA, Complementary; D004276:DNA, Satellite; D004926:Escherichia coli / Q000235:genetics; D005091:Exons; D006801:Humans; D007438:Introns; D008969:Molecular Sequence Data; D010727:Phosphoric Diester Hydrolases; D010786:Photoreceptor Cells / Q000201:enzymology*; D011995:Recombination, Genetic; D012091:Repetitive Sequences, Nucleic Acid; D012160:Retina / Q000201:enzymology
D018076:DNA, Complementary; D004276:DNA, Satellite; D010727:Phosphoric Diester Hydrolases; D015106:3',5'-Cyclic-GMP Phosphodiesterases; D054707:Cyclic Nucleotide Phosphodiesterases, Type 6; C517431:PDE6B protein, human
Organizatsiia gena beta-sub''edinitsy fotoretseptornoĭ fosfodiésterazy tsiklicheskogo GMP cheloveka.