title: Heterotrimeric G proteins.
abstract: Over the past year, the thrust of work in the field of heterotrimeric G proteins has been primarily in the following areas: first, resolution of their three-dimensional structures by X-ray crystallography; second, elucidation of the effect of lipid modifications on the Galpha and Ggamma subunits; third, understanding the role of the Gbetagamma dimer in stimulation of a variety of effectors following receptor activation; and fourth, identification of the points of contact among the Galpha, Gbeta, and Ggamma subunits, and between these subunits and their cognate receptor or effector molecules.
authors.affiliation: University of Illinois at Chicago, Department of Physiology and Biophysics, 835 S Wolcott, Chicago, IL 60612, USA.
authors.forename: H E
authors.initials: HE
authors.lastname: Hamm
authors.forename: A
authors.initials: A
authors.lastname: Gilchrist
mesh_terms: D000818:Animals; D019204:GTP-Binding Proteins / Q000737:chemistry / Q000378:metabolism*; D006160:Guanosine Triphosphate / Q000378:metabolism; D006801:Humans; D006868:Hydrolysis; D015394:Molecular Structure
chemical_list: D006160:Guanosine Triphosphate; D019204:GTP-Binding Proteins