Hypergastrinemia following gastrocystoplasty in rats.
Gastrocystoplasty has been previously described as an effective method of bladder augmentation or replacement. Twenty-four female Wistar rats were divided into three groups of eight animals each: control (G1), partial gastrectomy with the gastric body (G2) and gastrocystoplasty with the gastric body (G3). The period of observation was 2 months and the parameter assessed was serum gastrin. Increases in serum gastrin were seen in 62.5% (5/8) of rats in group 2 and in 50% (4/8) of rats in group 3. Our results suggest that, in rats, hypergastrinemia is induced by the partial surgical removal of the gastric body and is not due to gastrocystoplasty.
Ortiz
V
V
Department of Surgery, Escola Puulista de Medicina, São Paulo, Brazil.
Goldenberg
S
S
D000818:Animals; D005260:Female; D005753:Gastric Mucosa / Q000378:metabolism / Q000601:surgery; D005755:Gastrins / Q000097:blood*; D009929:Organ Size; D051381:Rats; D017208:Rats, Wistar; D013270:Stomach / Q000601:surgery*; D001743:Urinary Bladder / Q000601:surgery*; D014549:Urinary Incontinence / Q000601:surgery; D016476:Urinary Reservoirs, Continent / Q000379:methods
D005755:Gastrins