title: Detection of anti-neutrophil cytoplasmic antibodies after acute Plasmodium falciparum malaria.
abstract: Four of 30 patients with Plasmodium falciparum infection in Bangkok, Thailand, were positive for anti-neutrophil cytoplasmic antibodies by indirect immunofluorescence 1 month after antimalarial therapy. No myeloperoxidase, proteinase 3, lactoferrin, or elastase reactivity was found. Since no evidence of vasculitis was seen in these patients, anti-neutrophil cytoplasmic antibody production in malaria-infected susceptible patients probably represents a secondary response, indicating neutrophil activation.
authors.affiliation: Department of Infectious Diseases, Internal Medicine I, University Hospital of Vienna, Austria.
authors.forename: C
authors.initials: C
authors.lastname: Wenisch
authors.forename: H
authors.initials: H
authors.lastname: Wenisch
authors.forename: H C
authors.initials: HC
authors.lastname: Bankl
authors.forename: M
authors.initials: M
authors.lastname: Exner
authors.forename: W
authors.initials: W
authors.lastname: Graninger
authors.forename: S
authors.initials: S
authors.lastname: Looareesuwan
authors.forename: H
authors.initials: H
authors.lastname: Rumpold
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000818:Animals; D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies / Q000097:blood*; D016022:Case-Control Studies; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D016778:Malaria, Falciparum / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000276:immunology; D010963:Plasmodium falciparum / Q000276:immunology*
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D001323:Autoantibodies