title: Surface analysis of IgM-expressing bovine lymphocytes in BLV-infected cattle by immuno-scanning electron microscopy.
abstract: Surface of IgM-expressing lymphocytes infected by bovine leukemia virus and with/without persistent lymphocytosis (BLV+PL-, BLV+PL+) in cattle is heterogenous. Three distinct morphological structures of B lymphocytes were found in these groups by immuno-scanning electron microscopy (ISEM). B lymphocytes with generally elongated and pleomorphic microvilli and sometimes short ruffles were observed in infected, and as well as in non-infected animals. A second morphological type endowed with a relatively small number of elongated villi-like veils, and a third morphological type characterized by a relatively small number of short microvilli or blunt stub-like microvilli covering the smooth surface were seen, mainly in BLV+PL+ and seldom in BLV+PL- Cells of the second type were more intensively labeled, than lymphocytes of the third type.
authors.affiliation: Department of Pathological Anatomy, University of Veterinary Medicine, Kosice, Slovakia.
authors.forename: M
authors.initials: M
authors.lastname: Levkut
authors.forename: W
authors.initials: W
authors.lastname: Ponti
authors.forename: M
authors.initials: M
authors.lastname: Levkutova
authors.forename: L
authors.initials: L
authors.lastname: Turin
authors.forename: G
authors.initials: G
authors.lastname: Poli
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000378:metabolism; D002417:Cattle; D016583:Enzootic Bovine Leukosis / Q000097:blood*; D005260:Female; D007075:Immunoglobulin M / Q000097:blood*; D001909:Leukemia Virus, Bovine; D008214:Lymphocytes / Q000378:metabolism* / Q000821:virology; D016253:Microscopy, Immunoelectron
chemical_list: D007075:Immunoglobulin M