title: [Twenty one years of hemodialysis in a patient with primary hyperoxaluria].
abstract: We report a male patient with primary hyperoxaluria from childhood who survived more than 21 years on conventional haemodialysis. Despite the severity of his bone disease, he was married and actively employed up until 2 years before his death. His condition really worsened a few months before his death. He presented with only renal and bone involvement and had hardly any cardiovascular complications, that was probably a reason for his prolonged survival. Such an evolution is very unusual and we speculate that the length of haemodialysis sessions in addition to the large surface of the membrane probably contributed to such an outcome. During the time period on HD, anemia was transiently controlled by recombinant erythropoietin despite oxalate involvement of the marrow. He was refused a liver-kidney transplant and died from malnourishment at 43 years of age. To our knowledge, such an outcome has not yet been reported. It shows that careful prolonged hemodialysis sessions should be helped in admet patients without severe cardiovascular involvement.
authors.affiliation: Association Grenobloise pour la Dialyse des Urémiques Chroniques (AGDUC), Grenoble.
authors.forename: T
authors.initials: T
authors.lastname: Hachache
authors.forename: H
authors.initials: H
authors.lastname: Meftahi
authors.forename: M
authors.initials: M
authors.lastname: Forêt
authors.forename: R
authors.initials: R
authors.lastname: Milongo
authors.forename: F
authors.initials: F
authors.lastname: Kuentz
authors.forename: P
authors.initials: P
authors.lastname: Gaudin
authors.forename: J
authors.initials: J
authors.lastname: Maurizi
authors.forename: J
authors.initials: J
authors.lastname: Vallin
authors.forename: D J
authors.initials: DJ
authors.lastname: Cordonnier
mesh_terms: D000328:Adult; D004921:Erythropoietin / Q000627:therapeutic use; D006801:Humans; D006960:Hyperoxaluria, Primary / Q000150:complications / Q000628:therapy*; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000628:therapy; D008297:Male; D011994:Recombinant Proteins / Q000627:therapeutic use; D006435:Renal Dialysis; D013997:Time Factors
chemical_list: D011994:Recombinant Proteins; D004921:Erythropoietin
vernacular_title: Vingt et un ans d'hémodialyse chez un patient atteint d'hyperoxalurie primitive.