title: Progressive extrapyramidal disorder with primary hypogonadism and alopecia in sibs: a new syndrome?
abstract: We report on 2 sibs with consanguineous parents, and an identical progressive extrapyramidal movement disorder with onset in adolescence and associated with progressive alopecia and primary hypogonadism. To our knowledge, this syndrome has not been reported, and probably represents a newly recognized autosomal recessive condition.
authors.affiliation: Center for Human Genetics, University of Leuven, Belgium.
authors.forename: K
authors.initials: K
authors.lastname: Devriendt
authors.forename: E
authors.initials: E
authors.lastname: Legius
authors.forename: J P
authors.initials: JP
authors.lastname: Fryns
mesh_terms: D000328:Adult; D000505:Alopecia / Q000235:genetics / Q000503:physiopathology; D001480:Basal Ganglia Diseases / Q000235:genetics / Q000503:physiopathology; D003241:Consanguinity; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007006:Hypogonadism / Q000235:genetics / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D013577:Syndrome