Cloning and sequence analysis of a hypothalamic cDNA encoding a D1c dopamine receptor in tilapia.
Physiological and pharmacological studies have indicated that during acid stress a D1-like dopamine receptor becomes functional on intermediate pituitary melanocyte-stimulating hormone cells of tilapia (Oreochromis mossambicus). As a first step towards physiological expression studies we isolated a D1-like dopamine receptor from a tilapia hypothalamus cDNA library. Construction of a phylogenetic tree of most of the D1-like receptors known in human, rat, Xenopus, goldfish and Drosophila revealed that the here presented clone is most likely the tilapia equivalent of the Xenopus D1c dopamine receptor.
Lamers
A E
AE
Department of Animal Physiology, Faculty of Science, University of Nijmegen, The Netherlands.
Gröneveld
D
D
de Kleijn
D P
DP
Geeraedts
F C
FC
Leunissen
J A
JA
Flik
G
G
Wendelaar Bonga
S E
SE
Martens
G J
GJ
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics; D007031:Hypothalamus / Q000502:physiology*; D008969:Molecular Sequence Data; D010802:Phylogeny; D017447:Receptors, Dopamine D1 / Q000145:classification / Q000235:genetics*; D012641:Selection, Genetic; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity; D017210:Tilapia / Q000235:genetics*
D018076:DNA, Complementary; D017447:Receptors, Dopamine D1; C100987:dopamine D1C receptor