Near-infrared spectroscopy as a tool to improve quality.
Near-infrared spectroscopy, together with a polar qualification system, is an ideal technique to distinguish between identical pharmaceutical substances differing only slightly in chemical or physical characteristics. Among the attractive application of this powerful combination are the more precise definition and selection of starting materials used in the manufacturing of medicinal products and its use in blending validation.
Plugge
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Gist-Brocades B.V., Industrial Pharmaceutical Products Division, Delft, The Netherlands.
van der Vlies
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D002626:Chemistry, Pharmaceutical / Q000379:methods*; D007785:Lactose / Q000032:analysis; D008433:Mathematics; D010316:Particle Size; D012680:Sensitivity and Specificity; D019265:Spectroscopy, Near-Infrared / Q000379:methods*
D007785:Lactose