The effect of topical fluoride agents on saliva secretion.
The aim of this study was to assess the possible influence of various topical fluoride agents on the rate of saliva secretion. Fifteen healthy volunteers, both males and females, aged 20-60 years, participated in this study. Aminfluorides and monofluorophosphate products in gel, toothpaste and rinse states were used. Each subject brushed or rinsed the teeth and mouth for 2 minutes. Secreted saliva was collected for 5 minutes. Salivary secretion was significantly greater after toothbrushing with aminfluoride compounds as compared to toothbrushing with monofluorophosphate. There was a tendency for an increased saliva flow rate with higher fluoride concentration of the aminfluoride.
Engel-Brill
N
N
Hebrew University, Hadassah School of Dental Medicine, Jerusalem, Israel.
Gedalia
I
I
Raxn
F
F
Friedwald
E
E
Rotmann
M
M
Rosen
L
L
D000328:Adult; D000588:Amines / Q000008:administration & dosage / Q000494:pharmacology; D002327:Cariostatic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005459:Fluorides / Q000008:administration & dosage / Q000494:pharmacology; D005460:Fluorides, Topical / Q000008:administration & dosage / Q000494:pharmacology*; D005782:Gels; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes; D010710:Phosphates / Q000008:administration & dosage / Q000494:pharmacology; D012463:Saliva / Q000187:drug effects* / Q000378:metabolism; D012636:Secretory Rate / Q000187:drug effects; D014002:Tin Fluorides / Q000008:administration & dosage / Q000494:pharmacology; D014099:Toothbrushing; D014100:Toothpastes
D000588:Amines; D002327:Cariostatic Agents; D005460:Fluorides, Topical; D005782:Gels; D009067:Mouthwashes; D010710:Phosphates; D014002:Tin Fluorides; D014100:Toothpastes; C094808:amine fluoride solution; C012980:fluorophosphate; C075174:amine fluoride gel; D005459:Fluorides