T-cell repertoire: political correctness in the immune system.
Recent studies of T-cell development in various types of mutant mouse shed new light on the relative roles in T-cell selection of antigen versus MHC molecule recognition by T-cell receptors.
Lucas
B
B
Lymphocyte Biology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892-1892, USA.
Germain
R N
RN
D000818:Animals; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D000949:Histocompatibility Antigens Class II / Q000276:immunology*; D008285:Major Histocompatibility Complex; D018448:Models, Immunological; D011948:Receptors, Antigen, T-Cell / Q000276:immunology*; D013950:Thymus Gland / Q000166:cytology / Q000276:immunology*
D000949:Histocompatibility Antigens Class II; D011948:Receptors, Antigen, T-Cell