Cell line banks and their role in cancer research.
The utility of centralized cell banks in providing reference cultures for cancer research is reviewed. Procedures applied at The American Type Culture Collection in development, maintenance and expansion of such a resource are discussed for example, with emphasis on human tumor cell lines. The various categories of cell-line holdings are explained, and status with regard both to the numbers of lines available and distribution experienced are documented. The locations of other national cell repositories plus contact data are provided.
Hay
R J
RJ
Cell Culture Department, American Type Culture Collection, Rockville, Maryland 20852, USA.
Reid
Y A
YA
McClintock
P R
PR
Chen
T R
TR
Macy
M L
ML
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D018070:Biological Specimen Banks / Q000191:economics / Q000458:organization & administration; D018929:Cell Culture Techniques / Q000379:methods; D002648:Child; D002675:Child, Preschool; D003132:Commerce / Q000191:economics / Q000331:legislation & jurisprudence; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D006801:Humans; D006825:Hybridomas / Q000166:cytology; D007223:Infant; D007255:Information Services; D007621:Karyotyping; D008297:Male; D008495:Medical Oncology / Q000379:methods*; D008875:Middle Aged; D012106:Research; D013048:Specimen Handling; D014407:Tumor Cells, Cultured
D004273:DNA, Neoplasm