title: Pediatric cardiopulmonary bypass: a review of current practice.
abstract: Devices and techniques used for pediatric cardiopulmonary bypass are ever changing. There are frequently reports in the literature about new techniques and new devices. Periodic surveys are helpful because they reveal the actual extent to which these techniques and devices are applied to clinical practice. Advances in research are bringing about a better understanding of the intricate aspects of CPB and the effects of CPB on pediatric patients. There appears to be a trend from widely divergent approaches to CPB for pediatric patients to more uniformity in practice. For example, the use of membrane oxygenation and arterial line filtration has become universal, and there is an increase in the use of all types of safety devices. Techniques reported in the medical literature at the beginning of the decade, such as, the use of modified ultrafiltration, the use of centrifugal cell washers to process packed red blood cells before adding them to the prime, and the use of the antifibrinolytic drug, aprotinin, have become part of practice at a large number of pediatric heart centers. Periodic surveys are useful, as they provide a measurement of current practice. They also provide a historical record of the advances in the field.
authors.affiliation: Perfusion Department, Virginia Heart Center at Fairfax Hospital, Falls Church, USA.
authors.forename: R C
authors.initials: RC
authors.lastname: Groom
authors.forename: B F
authors.initials: BF
authors.lastname: Akl
authors.forename: R
authors.initials: R
authors.lastname: Albus
authors.forename: E A
authors.initials: EA
authors.lastname: Lefrak
mesh_terms: D000933:Antifibrinolytic Agents / Q000627:therapeutic use; D007611:Aprotinin / Q000627:therapeutic use; D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass / Q000295:instrumentation / Q000379:methods / Q000639:trends; D002648:Child; D004867:Equipment Design; D004869:Equipment Safety; D017707:Erythrocyte Transfusion / Q000379:methods; D006440:Hemofiltration / Q000295:instrumentation; D006490:Hemostatics / Q000627:therapeutic use; D006801:Humans; D010107:Oxygenators, Membrane; D014462:Ultrafiltration
chemical_list: D000933:Antifibrinolytic Agents; D006490:Hemostatics; D007611:Aprotinin