Comparison of centrifugal and roller pump hemolysis rates at low flow.
We compared in vitro rates of hemolysis for a recently developed centrifugal pump with a conventional roller pump (10-10-00; Stöckert, Munich, Germany). Flow rates of 0.3 L/min and 1 L/min and a pressure of 200 mm Hg were chosen to simulate conditions during neonatal extracorporeal membrane oxygenation (ECMO). There was no significant difference in hemolysis rates between centrifugal and roller pumps (p = 0.57) nor between high and low flow (p = 0.86). The centrifugal pump caused no more blood trauma than the roller pump at the low-flow/high-pressure conditions required for neonatal ECMO. The Nikkiso pump is superior to roller pumps in size and priming volume (25 ml) and may permit development of a smaller and simpler ECMO system.
Moon
Y S
YS
Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.
Ohtsubo
S
S
Gomez
M R
MR
Moon
J K
JK
Nosé
Y
Y
D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D002417:Cattle; D002498:Centrifugation; D004912:Erythrocytes / Q000166:cytology / Q000473:pathology; D015199:Extracorporeal Membrane Oxygenation / Q000009:adverse effects / Q000592:standards* / Q000639:trends; D006454:Hemoglobins / Q000032:analysis; D006461:Hemolysis; D066298:In Vitro Techniques; D011312:Pressure
D006454:Hemoglobins