title: Labelling of uric acid and allantoin in different purine organs and urine of the rat.
abstract: We studied the incorporation of 14C-formate into uric acid and allantoin in different organs (liver, lung, kidney, spleen), isolated hepatocytes, perfused liver and urine of the rat. Allantoin had a higher specific radioactivity than uric acid after 14C-formate load in the liver in vivo. This was found to be a strictly hepatic phenomenon and not due to the influence of other tissues.
authors.affiliation: Istituto di Biochimica e di Enzimologia, Università di Siena, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Pizzichini
authors.forename: M L
authors.initials: ML
authors.lastname: Pandolfi
authors.forename: L
authors.initials: L
authors.lastname: Arezzini
authors.forename: L
authors.initials: L
authors.lastname: Terzuoli
authors.forename: L
authors.initials: L
authors.lastname: Fe
authors.forename: F
authors.initials: F
authors.lastname: Bontemps
authors.forename: G
authors.initials: G
authors.lastname: Van den Berghe
authors.forename: E
authors.initials: E
authors.lastname: Marinello
mesh_terms: D000481:Allantoin / Q000378:metabolism* / Q000652:urine; D000818:Animals; D002250:Carbon Radioisotopes; D005561:Formates / Q000378:metabolism*; D007553:Isotope Labeling; D007668:Kidney / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000378:metabolism; D008168:Lung / Q000378:metabolism; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000378:metabolism; D014527:Uric Acid / Q000378:metabolism* / Q000652:urine
chemical_list: D002250:Carbon Radioisotopes; D005561:Formates; C030544:formic acid; D014527:Uric Acid; D000481:Allantoin