[Invasive amebiasis at an institution for the mentally retarded in Shizuoka Prefecture].
Amebiasis caused by Entamoeba histolytica at an institution for mentally retarded in Shizuoka Prefecture is reported. Five of the 50 patients showed E. histolytica cysts in their stools and 4 were positive serologically. The polymerase chain reaction and restriction fragment length polymorphism revealed that the isolates were pathogenic-type E. histolytica. Epidemiological analysis revealed that the amebic infection was caused by the abnormal behavior of mentally retarded patients. Administration of diloxanide furoate and metronidazole for cyst-carriers eliminated cysts from the stool and lowered the antibody titer.
Sahara
K
K
Shizuoka Prefectural Institute of Public Health and Environmental Science.
Hori
W
W
Masuda
T
T
Ohata
K
K
Yamazaki
F
F
Akahane
S
S
Hattori
H
H
Yuasa
H
H
Hashizume
I
I
Tanaka
Y
Y
Nagakura
K
K
Tachibana
H
H
D000328:Adult; D000818:Animals; D004748:Entamoeba histolytica / Q000302:isolation & purification; D004749:Entamoebiasis / Q000453:epidemiology* / Q000209:etiology / Q000469:parasitology; D005260:Female; D006801:Humans; D007326:Institutionalization; D008607:Intellectual Disability / Q000150:complications*; D007564:Japan / Q000453:epidemiology; D008297:Male