Fictive locomotion in the adult decerebrate rat.
In adult immobilised, decerebrate rats, administration of L-3,4-dihydroxyphenylalanine, stimulation of the mesencephalic locomotor centre, or a combination of the two elicited fictive locomotor patterns in hindlimb muscle nerves. The patterns correspond closely to those observed in decerebrate animals that were free to move.
Iles
J F
JF
Department of Zoology, University of Oxford, UK.
Nicolopoulos-Stournaras
S
S
D006916:5-Hydroxytryptophan / Q000494:pharmacology; D000367:Age Factors; D000818:Animals; D003655:Decerebrate State / Q000503:physiopathology*; D015259:Dopamine Agents / Q000494:pharmacology; D004525:Efferent Pathways / Q000502:physiology; D004568:Electrodiagnosis; D007980:Levodopa / Q000494:pharmacology; D008124:Locomotion / Q000187:drug effects / Q000502:physiology*; D008636:Mesencephalon / Q000166:cytology / Q000502:physiology; D009046:Motor Neurons / Q000502:physiology; D051381:Rats
D015259:Dopamine Agents; D007980:Levodopa; D006916:5-Hydroxytryptophan