The liver as origin and target of reactive intermediates exemplified by the progesterone derivative, cyproterone acetate.
Schwarz
L R
LR
GSF-Forschungszentrum für Umwelt und Gesundheit, Institut fur Toxikologie, Neuherberg, Germany.
Werner
S
S
Topinka
J
J
Andrae
U
U
Neumann
I
I
Wolff
T
T
D000818:Animals; D001711:Biotransformation / Q000502:physiology; D056486:Chemical and Drug Induced Liver Injury / Q000201:enzymology / Q000378:metabolism*; D017373:Cyproterone Acetate / Q000378:metabolism / Q000633:toxicity*; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D018736:DNA Adducts / Q000378:metabolism; D016172:DNA Fingerprinting; D004260:DNA Repair; D005260:Female; D005609:Free Radicals / Q000378:metabolism; D006728:Hormones / Q000378:metabolism / Q000633:toxicity*; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013431:Sulfates / Q000378:metabolism; D014018:Tissue Distribution
D018736:DNA Adducts; D005609:Free Radicals; D006728:Hormones; D013431:Sulfates; D017373:Cyproterone Acetate; D003577:Cytochrome P-450 Enzyme System