title: Prevention of sepsis in total joint arthroplasty.
abstract: Because of the adoption of effective prophylactic measures such as improved operating room techniques and systemic antibiotics, the prosthetic infection rate for artificial joint procedures has been reduced to 1-2%. However, because of the devastating results and large number of prosthetic procedures, prosthetic infection remains a major challenge. Common pathogens and mechanisms of infection, methods of preventing bacterial adherence to biomaterial surfaces, and clinical preventive strategies for prosthetic infections are discussed.
authors.affiliation: Department of Orthopaedic Surgery, Medical University of South Carolina, Charleston 29425, USA.
authors.forename: Y H
authors.initials: YH
authors.lastname: An
authors.forename: R J
authors.initials: RJ
authors.lastname: Friedman
mesh_terms: D001422:Bacterial Adhesion; D004866:Equipment Contamination; D006801:Humans; D017053:Infection Control / Q000379:methods*; D007595:Joint Prosthesis / Q000009:adverse effects*; D016459:Prosthesis-Related Infections / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control*; D018805:Sepsis / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control*