Right ventricular pathology in chronic pulmonary hypertension.
Right ventricular free wall biopsy specimens in 40 patients undergoing surgery for relief of chronic thromboembolic pulmonary hypertension were normal in 5%, disclosed only myocyte hypertrophy in 80%, mild focal fibrosis in 12.5%, and myocarditis in 2.5%. There was no relation between postsurgical functional or hemodynamic outcomes and the presence of focal fibrosis.
Bradley
S P
SP
Department of Medicine, University of California San Diego Medical Center, USA.
Auger
W R
WR
Moser
K M
KM
Fedullo
P F
PF
Channick
R N
RN
Bloor
C M
CM
D000368:Aged; D001706:Biopsy; D002908:Chronic Disease; D005260:Female; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*; D018497:Ventricular Dysfunction, Right / Q000473:pathology* / Q000503:physiopathology