Rhabdomyolysis following administration of cyclophosphamide: a case report in a BMT recipient.
Massive rhabdomyolysis followed by myocardial necrosis was observed in a 14-year-old patient undergoing allogeneic bone marrow transplantation for severe aplastic anemia. Rhabdomyolysis was preceded by the administration of cyclophosphamide as part of a preparative regimen for transplantation Although the specific etiology of this rhabdomyolysis is still unknown, an association with high-dose cyclophosphamide should be noted.
Tabata
N
N
Department of Pediatrics, Mie University School of Medicine, Japan.
Tanaka
R
R
Suga
S
S
Mitani
Y
Y
Nakano
T
T
Ido
M
M
Azuma
E
E
Ito
M
M
Hamazaki
M
M
Shiraishi
T
T
Sakurai
M
M
D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002648:Child; D003520:Cyclophosphamide / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D012206:Rhabdomyolysis / Q000139:chemically induced*; D019172:Transplantation Conditioning / Q000009:adverse effects
D007166:Immunosuppressive Agents; D003520:Cyclophosphamide