title: Neurogenesis in the insect central nervous system.
abstract: Recent advances provide an increasingly sophisticated understanding of Drosophila CNS development. First, genes have been identified that specify unique neuroblast cell fates. Second, neuroblasts have been found to use a novel mechanism for asymmetric localization of proteins into one daughter cell at mitosis. Third, a gene controlling the choice between glial/neuronal determination has been discovered. And finally, new cell-lineage methods are being used to determine the entire lineage of identified neuroblasts, including axon projections and synaptic contacts.
authors.affiliation: Department of Cell and Structural Biology, University of Illinois, Urbana 61801, USA. c-doe@uiuc.edu
authors.forename: C Q
authors.initials: CQ
authors.lastname: Doe
authors.forename: J B
authors.initials: JB
authors.lastname: Skeath
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000254:growth & development*; D005724:Ganglia / Q000502:physiology; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology*