[The vasoactive action of kurantil in patients with chronic glomerulonephritis].
The immediate positive result of 3-4 weeks' course of treatment with curantyl (C) of patients with chronic glomerulonephritis (ChGN) is due to both vasoactive and antiaggregant action of the preparation. The negative immediate result of C treatment appear to be associated with <<steal syndrome>>. C was found to be usefull in treatment of ChGN patients presenting with predominance of fibroplastic changes in the kydneys, those with arterial hypertension, grade I ChGN. Analysis of late results of treatment 1.5-2 years after C withdrawal revealed improvement in health status in 22.5% and slowing down ChGN progression in 15% of patients compared to the control group.
Kolesnyk
M O
MO
Lapchyns'ka
I I
II
Pryshchepa
P P
PP
D000293:Adolescent; D000328:Adult; D016009:Chi-Square Distribution; D002908:Chronic Disease; D004176:Dipyridamole / Q000627:therapeutic use*; D004341:Drug Evaluation; D005260:Female; D005921:Glomerulonephritis / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012074:Remission Induction; D013997:Time Factors; D014665:Vasodilator Agents / Q000627:therapeutic use*
D014665:Vasodilator Agents; D004176:Dipyridamole