Primary primitive neuroectodermal tumor of the kidney. Case report and review of the literature.
Small cell tumors are a heterogeneous group of neoplasms with similar morphologic features. They include lymphomas, carcinomas with variable degrees of neuroendocrine differentiation, rhabdomyosarcomas, and neuroblastomas. The authors describe a rare case of primitive neuroectodermal tumor (PNET) located in the kidney that was thoroughly studied with modern diagnostic techniques, including expression of protein P 30/32 MIC2 with the antibody 013 with subsequent demonstration of a genetic translocation consistent with t(11;22). The literature on small cell tumors of the kidney, with special emphasis on PNET, is reviewed.
Furman
J
J
Department of Pathology, University of Florida, College of Medicine, Gainesville 32610, USA.
Murphy
W M
WM
Jelsma
P F
PF
Garzotto
M G
MG
Marsh
R D
RD
D000328:Adult; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000737:chemistry / Q000473:pathology*; D018242:Neuroectodermal Tumors, Primitive / Q000737:chemistry / Q000473:pathology*