title: Presynaptic potassium channels.
abstract: The past year has witnessed some significant improvements in our understanding of the molecular diversity, subunit composition, and functional properties of K+ channels in heterologous expression systems. Immunocytochemical studies have yielded important information on the localization of K+ channel proteins to synaptic terminals in mammalian brain. Although a coherent picture of native presynaptic K+ channels' function in the mammalian central nervous system is not yet available, it may emerge from improvements in patch-clamp techniques and new applications of targeted knock-out technologies.
authors.affiliation: Zentrum für Molekulare Neurobiologie, Institut für neurale Signalverarbeitung, Martinistrasse 52, Haus 42, D-20246 Hamburg, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Roeper
authors.forename: O
authors.initials: O
authors.lastname: Pongs
mesh_terms: D000818:Animals; D002490:Central Nervous System / Q000378:metabolism; D004330:Drosophila / Q000378:metabolism; D004594:Electrophysiology; D006801:Humans; D008322:Mammals / Q000378:metabolism; D009420:Nervous System / Q000378:metabolism; D015221:Potassium Channels / Q000378:metabolism* / Q000502:physiology; D017729:Presynaptic Terminals / Q000378:metabolism*; D013569:Synapses / Q000378:metabolism
chemical_list: D015221:Potassium Channels