title: European carotid angioplasty trial.
abstract: The Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS) is an international multicenter randomized trial, the primary aims of which are: (1) to determine the risks and benefits of carotid and vertebral artery transluminal angioplasty; and (2) to compare these with surgical treatment (carotid endarterectomy) or best medical treatment. Through the end of October 1995, 193 patients have been randomized (90 at our center). In this article, the rationale for the trial, its design and protocol, and the experience of our institution within the trial will be discussed.
authors.affiliation: Department of Neurology, Royal Hallamshire Hospital, Sheffield, United Kingdom.
authors.forename: A
authors.initials: A
authors.lastname: Sivaguru
authors.forename: G S
authors.initials: GS
authors.lastname: Venables
authors.forename: J D
authors.initials: JD
authors.lastname: Beard
authors.forename: P A
authors.initials: PA
authors.lastname: Gaines
mesh_terms: D000800:Angioplasty, Balloon / Q000706:statistics & numerical data; D001157:Arterial Occlusive Diseases / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D001241:Aspirin / Q000627:therapeutic use; D002340:Carotid Artery Diseases / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D002343:Carotid Artery, Internal; D016893:Carotid Stenosis / Q000188:drug therapy / Q000601:surgery / Q000628:therapy; D002985:Clinical Protocols; D016894:Endarterectomy, Carotid; D005060:Europe; D005500:Follow-Up Studies; D006801:Humans; D007391:International Cooperation; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D012107:Research Design; D012306:Risk; D016896:Treatment Outcome; D014711:Vertebral Artery
chemical_list: D010975:Platelet Aggregation Inhibitors; D001241:Aspirin