title: Massive pelvic hemorrhage during gynecologic cancer surgery: "pack and go back".
abstract: Over a 13-year period, intraabdominal packing has been used to control massive hemorrhage during surgery for gynecologic malignancy in six patients. Five patients had undergone total pelvic exenteration and one total abdominal hysterectomy with bilateral salpingo-oophorectomy for endometrial cancer. Massive hemorrhage was defined as infusion of more than 10 units of blood and replacement of more than one total blood volume. Tamponade was performed using continuous Kerlex rolls (Kendall Co., Boston, MA) in a bowel bag with directed pressure over the hemorrhaging site with abdominal closure. The packs were removed in 48 to 72 hr in the operating room, transabdominally in five patients and transvaginally in one. One postoperative death occurred within 8 hr of surgery. The packing was ultimately successful in the five remaining patients. In five of six patients, tumors were removed before the packing, whereas in one, the tumor was removed concurrently with the pack. In one patient, immediate repacking was required after pack removal, with ultimate hemostasis. Morbidity included "empty pelvis syndrome" in four patients, neuropathy in three (obturator in 1, sciatic in 2), and small bowel obstruction in one. In patients with severe intraoperative hemorrhage, intraabdominal packing has been successful as a mode of treatment.
authors.affiliation: Department of Obstetrics and Gynecology, Ochsner Clinic, New Orleans, Louisiana 70121, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Finan
authors.forename: J V
authors.initials: JV
authors.lastname: Fiorica
authors.forename: M S
authors.initials: MS
authors.lastname: Hoffman
authors.forename: D P
authors.initials: DP
authors.lastname: Barton
authors.forename: N
authors.initials: N
authors.lastname: Gleeson
authors.forename: W S
authors.initials: WS
authors.lastname: Roberts
authors.forename: D
authors.initials: D
authors.lastname: Cavanagh
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016063:Blood Loss, Surgical / Q000517:prevention & control; D016889:Endometrial Neoplasms / Q000601:surgery*; D005260:Female; D006487:Hemostasis / Q000502:physiology; D006801:Humans; D007044:Hysterectomy / Q000009:adverse effects*; D015994:Incidence; D008026:Ligation; D008875:Middle Aged; D009017:Morbidity; D010388:Pelvis; D011183:Postoperative Complications / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D011312:Pressure; D012086:Reoperation; D013630:Tampons, Surgical / Q000592:standards*