title: Crohn's disease in a 92-year-old male.
abstract: A case of Crohn's disease in an extremely elderly man (92-years-old) is reported. He was admitted for abdominal pain and was operated on under a diagnosis of ischemic colitis. At the mucosal surface, many linear and irregularly shaped shallow ulcers were found on the mesenteric side. Microscopically, transmural inflammatory cell infiltration, bead-like lymphoid aggregates around the propriate muscle, small epithelioid cell granulomas, fissure, and volcano-like streamers of inflammatory cells were found. Nerve fibers in Meissner's and Auerbach's plexi seemed to be increased in number, and some were hyperplastic. There was no feature of ischemic colitis or Yersinia enteritis. Serially sectioned tissue specimens did not show dysplastic mucosal change. Many cases of Crohn's disease in the elderly have been reported but an extremely elderly patient such as the present one is very rare, especially in Japan. Characteristics of elderly patients with Crohn's disease are discussed.
authors.affiliation: Department of Pathology, Mutsu General Hospital, Aomori, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Narita
authors.forename: M
authors.initials: M
authors.lastname: Akiyama
authors.forename: H
authors.initials: H
authors.lastname: Ohnuma
authors.forename: K
authors.initials: K
authors.lastname: Matsuda
mesh_terms: D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D003424:Crohn Disease / Q000473:pathology* / Q000601:surgery; D017809:Fatal Outcome; D005753:Gastric Mucosa / Q000473:pathology*; D006801:Humans; D007564:Japan; D008297:Male