Multiple evanescent white dot syndrome after hepatitis B vaccine.
OBJECTIVE
Hepatitis B vaccine has become an effective means of preventing complications of hepatitis B. However, it occasionally induces serious side effects. We report a case of multiple evanescent white dot syndrome (MEWDS) that occurred following hepatitis B vaccination.


METHODS
A 23-year-old woman with a one-week history of progressive loss of vision in the left eye and bilateral photopsia was referred for examination. Her symptoms appeared 24 hours after a booster intramuscular injection of hepatitis B vaccine.


RESULTS
Clinical examination, fluorescein angiography, and the course of events were typical of MEWDS.


CONCLUSIONS
This case demonstrates the occasional occurrence of MEWDS after hepatitis B vaccine and suggests that hepatitis B virus immunization may be a risk factor for this retinal condition.
Baglivo
E
E
Department of Ophthalmology, Geneva University Hospital, Switzerland. baglivo-edoardo@diogenes.hcuge.ch
Safran
A B
AB
Borruat
F X
FX
D000328:Adult; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006509:Hepatitis B / Q000517:prevention & control; D017325:Hepatitis B Vaccines / Q000009:adverse effects*; D006801:Humans; D012164:Retinal Diseases / Q000209:etiology* / Q000503:physiopathology; D012307:Risk Factors; D014611:Vaccination / Q000009:adverse effects*; D014786:Vision Disorders / Q000209:etiology / Q000503:physiopathology
D017325:Hepatitis B Vaccines