title: Clinical experience with the Nikkiso centrifugal pump.
abstract: The Nikkiso HPM-15 is a minimally sized centrifugal pump. Preliminary results regarding clinical use of this pump for cardiopulmonary bypass (CPB) procedures have been reported previously. Recently, we have managed some additional cases using a newly developed controller. This article reports our clinical experiences with the use of this pump. We have managed 23 cases with a Nikkiso centrifugal pump. Twenty-two patients underwent CPB and 1 patient with fulminant viral myocarditis underwent percutaneous cardiopulmonary support (PCPS). With this pump, the circuit was extremely easy to prepare and deaeration was achieved readily. Hemodynamics during CPB and PCPS were stable in all cases. The increase in serum-free hemoglobin levels during CPB with this pump was as low as that seen in preliminary tests. A decrease in the platelet count was observed after the initiation of CPB with this pump; however, platelet counts returned to preoperative values 7 days after surgery. Moreover, urine output during CPB with this pump was as high as that seen in preliminary tests. No abnormalities in renal or liver function occurred during CPB. It appears that this new centrifugal pump is safe and easy to operate, and we conclude that it is useful for CPB and PCPS.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Mie University School of Medicine, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Shomura
authors.forename: T
authors.initials: T
authors.lastname: Shimono
authors.forename: K
authors.initials: K
authors.lastname: Onoda
authors.forename: I
authors.initials: I
authors.lastname: Hioki
authors.forename: H
authors.initials: H
authors.lastname: Tenpaku
authors.forename: Y
authors.initials: Y
authors.lastname: Maze
authors.forename: T
authors.initials: T
authors.lastname: Mizumoto
authors.forename: K
authors.initials: K
authors.lastname: Tani
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: H
authors.initials: H
authors.lastname: Shimpo
authors.forename: H
authors.initials: H
authors.lastname: Yuasa
authors.forename: I
authors.initials: I
authors.lastname: Yada
mesh_terms: D000328:Adult; D000368:Aged; D000410:Alanine Transaminase / Q000032:analysis; D001663:Bilirubin / Q000032:analysis; D001806:Blood Urea Nitrogen; D002315:Cardiopulmonary Bypass / Q000379:methods*; D002498:Centrifugation; D005260:Female; D006353:Heart-Assist Devices / Q000592:standards*; D006439:Hemodynamics / Q000502:physiology*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007423:Intra-Aortic Balloon Pumping / Q000379:methods*; D007677:Kidney Function Tests; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D011786:Quality Control
chemical_list: D006454:Hemoglobins; D000410:Alanine Transaminase; D001663:Bilirubin