Infections in HIV-infected patients with malignancy.
With the increasing prevalence of HIV, better combination treatment regimens, and preventive therapy for opportunistic infections, physicians will be caring for an ever-increasing number of survivors with an ever-dwindling immune function. Increasing this burden is the unfortunate patient who also develops cancer concurrent with HIV infection. The combined risk factors of these diseases make a worst-case scenario in evaluation and treatment of infections. This article reviews AIDS-defining tumors and other malignancies, risk factors for infection, opportunistic infections, and therapy strategies.
Brown
M A
MA
Division of Infectious Diseases and Tropical Medicine, University of South Florida, Tampa, USA.
Nadler
J P
JP
D017088:AIDS-Related Opportunistic Infections / Q000150:complications*; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000401:mortality; D000328:Adult; D001344:Autopsy; D015658:HIV Infections / Q000150:complications* / Q000401:mortality; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000175:diagnosis; D008297:Male; D009369:Neoplasms / Q000150:complications*; D009503:Neutropenia / Q000150:complications; D009747:Nutritional Physiological Phenomena; D012307:Risk Factors; D012514:Sarcoma, Kaposi / Q000175:diagnosis