Intrinsic and extrinsic neuromodulation of motor circuits.
Neuromodulation of motor circuits by extrinsic inputs provides enormous flexibility in the production of behavior. Recent work has shown that neurons intrinsic to central pattern-generating circuits can evoke neuromodulatory effects in addition to their neurotransmitting actions. Modulatory neurons often elicit a multitude of different effects attributable to actions at different receptors and/or through the release of co-transmitters. Differences in neuromodulation between species can account for differences in behavior. Modulation of neuromodulation may provide an additional level of flexibility to motor circuits.
Katz
P S
PS
Department of Neurobiology and Anatomy, University of Texas Medical School, Houston 77225, USA. pkatz@nba19.med.uth.tmc.edu
D000818:Animals; D001519:Behavior / Q000502:physiology*; D001522:Behavior, Animal / Q000502:physiology; D006801:Humans; D008124:Locomotion / Q000502:physiology; D009046:Motor Neurons / Q000502:physiology*; D009434:Neural Pathways / Q000502:physiology