title: Radiographic small lung opacities and pleural abnormalities in relation to smoking, urbanization status, and occupational asbestos exposure in Finland.
abstract: The role of smoking and an urban living environment in the etiology of radiographic pleural and pulmonary abnormalities was studied in a population sample that was representative of the Finnish adult population. A total of 7095 full-size chest radiographs were classified according to the International Labor Organization's 1980 classification of radiographs of pneumoconioses, with some modifications. The risk of bilateral pleural plaques was significantly higher among urban men (RR, 2.0) and women (RR, 3.8), even when adjusted for age and probability of occupational asbestos exposure and smoking. The risks of small lung opacities and abnormalities of the visceral pleura were not higher in urban areas. Risks of small lung opacities and thickening of the visceral pleura were positively associated with smoking, and the risk of small lung opacities was also higher among smokers than never-smokers in the population fraction with unlikely occupational asbestos exposure.
authors.affiliation: Finnish Institute of Occupational Health, Helsinki, Finland.
authors.forename: A J
authors.initials: AJ
authors.lastname: Zitting
authors.forename: A
authors.initials: A
authors.lastname: Karjalainen
authors.forename: O
authors.initials: O
authors.lastname: Impivaara
authors.forename: T
authors.initials: T
authors.lastname: Kuusela
authors.forename: J
authors.initials: J
authors.lastname: Mäki
authors.forename: A
authors.initials: A
authors.lastname: Tossavainen
authors.forename: J
authors.initials: J
authors.lastname: Järvisalo
mesh_terms: D000328:Adult; D000368:Aged; D000393:Air Pollutants / Q000009:adverse effects*; D001194:Asbestos / Q000009:adverse effects*; D016001:Confidence Intervals; D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects* / Q000592:standards; D010994:Pleura / Q000000981:diagnostic imaging; D011009:Pneumoconiosis / Q000000981:diagnostic imaging / Q000453:epidemiology*; D011859:Radiography; D012306:Risk; D017678:Sex Distribution; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology*; D014504:Urban Health / Q000706:statistics & numerical data*
chemical_list: D000393:Air Pollutants; D001194:Asbestos