Selective depletion of mitochondrial glutathione content by pivalic acid and valproic acid in rat liver: possibility of a common mechanism.
Zanelli
U
U
Istituto di Mutagenesi e Differenziamento, Pisa, Italy.
Puccini
P
P
Acerbi
D
D
Ventura
P
P
Gervasi
P G
PG
D000818:Animals; D000927:Anticonvulsants / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology*; D005978:Glutathione / Q000378:metabolism*; D007274:Injections, Intraperitoneal; D008297:Male; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D010421:Pentanoic Acids / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D014635:Valproic Acid / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology*
D000927:Anticonvulsants; D010421:Pentanoic Acids; D014635:Valproic Acid; C005566:pivalic acid; D005978:Glutathione