A tangential neuronal migration in the olfactory bulbs of adult lizards.
Tritiated thymidine ([3H]thymidine) autoradiography at different times after experiments showed that postnatally generated neurones in the adult lizard olfactory bulbs are not generated in a local germinative zone but in the ventricular zone (VZ) of the cerebral hemispheres, which is a long distance from the olfactory bulbs. The new cells originating in the VZ of rostral telencephalon migrate to both main and accessory olfactory bulbs through the olfactory peduncle, along a highly restricted pathway orthogonal to the orientation of radial glial fibres. Our results suggest that the olfactory bulb interneurones of adult lizards may follow a tangential migration route from their germinative zone, as is the case in mammals.
Peñafiel
A
A
Departamento Biología Celular, Facultad de Ciencias, Universidad de Málaga, Spain.
Gutiérrez
A
A
Martín
R
R
Mar Pérez-Cañellas
M
M
de la Calle
A
A
D000818:Animals; D001345:Autoradiography; D001931:Brain Mapping; D002452:Cell Count; D002465:Cell Movement / Q000502:physiology; D002470:Cell Survival / Q000502:physiology; D004805:Ependyma / Q000166:cytology*; D008116:Lizards / Q000033:anatomy & histology*; D009474:Neurons / Q000166:cytology*; D009830:Olfactory Bulb / Q000166:cytology*; D013687:Telencephalon / Q000166:cytology*