title: Versatile molecular glue. Transcriptional control.
abstract: CBP and p300 are versatile coactivators that physically connect many DNA-binding factors to the basal transcription machinery. Phosphorylation by cyclin-dependent or signal-induced protein kinases may regulate their function.
authors.affiliation: The Salk Institute Molecular Biology and Virology Laboratory, 10010 North Torrey Pines Road, La Jolla, California 92037, USA.
authors.forename: R
authors.initials: R
authors.lastname: Janknecht
authors.forename: T
authors.initials: T
authors.lastname: Hunter
mesh_terms: D000123:Acetyltransferases; D000818:Animals; D050882:CREB-Binding Protein; D018797:Cell Cycle Proteins / Q000378:metabolism*; D000242:Cyclic AMP / Q000378:metabolism; D051548:Histone Acetyltransferases; D009687:Nuclear Proteins / Q000378:metabolism*; D010766:Phosphorylation; D011494:Protein Kinases / Q000378:metabolism; D015534:Trans-Activators; D014157:Transcription Factors / Q000378:metabolism*; D014158:Transcription, Genetic; D050880:p300-CBP Transcription Factors; D000099224:p300-CBP-Associated Factor
chemical_list: D000123:Acetyltransferases; D050882:CREB-Binding Protein; D018797:Cell Cycle Proteins; D000242:Cyclic AMP; D051548:Histone Acetyltransferases; D009687:Nuclear Proteins; D011494:Protein Kinases; D015534:Trans-Activators; D014157:Transcription Factors; D050880:p300-CBP Transcription Factors; D000099224:p300-CBP-Associated Factor