Immunochemical detection of drug-protein adducts in acetaminophen hepatotoxicity.
Hinson
J A
JA
Division of Toxicology, University of Arkansas for Medical Sciences, Little Rock 72205, USA.
Roberts
D W
DW
Halmes
N C
NC
Gibson
J D
JD
Pumford
N R
NR
D000082:Acetaminophen / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity*; D018712:Analgesics, Non-Narcotic / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity*; D000818:Animals; D015153:Blotting, Western; D056486:Chemical and Drug Induced Liver Injury / Q000378:metabolism* / Q000473:pathology; D002852:Chromatography, Ion Exchange; D003545:Cysteine / Q000737:chemistry; D003600:Cytosol / Q000378:metabolism; D007150:Immunohistochemistry; D008099:Liver / Q000378:metabolism / Q000473:pathology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D011506:Proteins / Q000737:chemistry / Q000378:metabolism*; D012643:Selenium / Q000494:pharmacology
D018712:Analgesics, Non-Narcotic; D011506:Proteins; D000082:Acetaminophen; D012643:Selenium; D003545:Cysteine