Mouse NK1.1+ T cells: a new family of T cells.
The NK1.1 antigen defines a subset of T cells that produce high titers of cytokines and express a restricted repertoire of T-cell receptors. Here, Alain Vicari and Albert Zlotnik discuss the characteristics of NK1.1+ T cells that distinguish them from the mainstream CD4+ helper or CD8+ cytotoxic families of T cells. It appears that NK1.1+ T cells may play major roles in the regulation of some immune responses.
Vicari
A P
AP
DNAX Research Institute, Palo Alto, CA 94304-1104, USA.
Zlotnik
A
A
D000818:Animals; D000941:Antigens / Q000276:immunology*; D000950:Antigens, Ly; D000954:Antigens, Surface; D006801:Humans; D007109:Immunity; D037181:Lectins, C-Type; D051379:Mice; D055651:NK Cell Lectin-Like Receptor Subfamily B; D011506:Proteins / Q000276:immunology*; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D000941:Antigens; D000950:Antigens, Ly; D000954:Antigens, Surface; C527203:KLRB1 protein, human; C527211:Klrb1c protein, mouse; D037181:Lectins, C-Type; D055651:NK Cell Lectin-Like Receptor Subfamily B; D011506:Proteins