title: does intravenous administration of human albumin prevent severe ovarian hyperstimulation syndrome?
abstract: OBJECTIVE
  To report our experience with i.v. albumin as a means to prevent ovarian hyperstimulation syndrome (OHSS) in high-risk patients.
  
  
  METHODS
  Retrospective case-series.
  
  
  METHODS
  University hospital-based IVF program.
  
  
  METHODS
  Five women undergoing controlled ovarian stimulation for IVF-Based on previous history and/or E2 measurements and number of ovarian follicles, these patients were considered to be at high risk for developing OHSS.
  
  
  METHODS
  Intravenous albumin was given at the time of oocyte retrieval. Additional doses were given 12 and 24 hours later.
  
  
  METHODS
  Development of OHSS.
  
  
  RESULTS
  Four patients developed OHSS; two of them had the severe form of the syndrome.
  
  
  CONCLUSIONS
  Severe OHSS may develop in high-risk patients despite the prophylactic administration of i.v. albumin.
authors.affiliation: Department of Obsterics and Gynecology, Rambam Medical Center, Haifa, Israel.
authors.forename: N
authors.initials: N
authors.lastname: Lewit
authors.forename: S
authors.initials: S
authors.lastname: Kol
authors.forename: N
authors.initials: N
authors.lastname: Ronen
authors.forename: J
authors.initials: J
authors.lastname: Itskovitz-Eldor
mesh_terms: D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D016471:Ovarian Hyperstimulation Syndrome / Q000517:prevention & control*; D012189:Retrospective Studies; D012709:Serum Albumin / Q000008:administration & dosage*
chemical_list: D012709:Serum Albumin