[Possibilities of preserving reproductive function after therapy for early malignancies of the cervix uteri, endometrium and ovaries].
Reproductive function was investigated in 155 females who had undergone organ-saving surgery for early forms of cervical carcinoma. Ninety-nine patients had their appendages unilaterally removed as part of therapy for ovarian malignancies, stage 1a. and 19 more who had received gestagen therapy for pre- and cancer of the endometrium. Menstrual function remained unimpaired in 99.3%. Changes in this function were observed postoperatively in 31 (20%) cases of cervical carcinoma. Paliative treatment for ovarian malignancies was followed by amenorrhea in 2 cases while changes in menstrual function-in 28 (28.3%). After hormone therapy those changes were registered in 11 (57.9%). One hundred and seven pregnancies in 75 (48.4%) patients were reported in group 1, 131 pregnancies in 72 (72.7%) -in group 2 and 16 pregnancies in 10 (52.6%) patients-in group 3. One hundred and thirteen babies were born after organ-saving surgery for early forms of cancer of the internal genitals perinatal mortality reaching 4.4%. Organ-saving therapy for early malignancies of the ovary, endometrium and cervix uteri has been found to be an effective means of treating the disease and maintaining certain specific functions of the female organism.
Chissov
V I
VI
Novikova
E G
EG
Antoshechkina
M A
MA
Chulkova
O V
OV
D000328:Adult; D016889:Endometrial Neoplasms / Q000601:surgery*; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000601:surgery*; D011247:Pregnancy; D011256:Pregnancy Outcome; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000601:surgery*