title: [Changes in the immunocompetent cell system of the peripheral blood in HIV carriage].
abstract: HIV-carriage is characterized by hematological signs such as normocytosis of the general leucocyte count and deviations within normal range of values for myeloid series cells (neutrophiles, eosinophiles, basophiles). A peculiar hematological sign seen in HIV-infection is a finding of a raised content of cellular elements of mononuclear type on a hemogramme of peripheral blood and consistent decrease in the level of small T-lymphocytes against the background of substantial growth of suppressor-killer populations (large lymphocytes and lymphocyte-like mononuclears) as evidenced by a mononucleorogramme of peripheral blood, which fact provide a mechanism of antiviral protection at early stages of HIV-infection. Such changes in hemogrammes of peripheral blood, consistently found in all virus carriers, may be used in clinical settings as an early diagnostic sign of HIV-infection.
authors.forename: V R
authors.initials: VR
authors.lastname: Karabanov
authors.forename: I S
authors.initials: IS
authors.lastname: Markov
authors.forename: N E
authors.initials: NE
authors.lastname: Marchenko
mesh_terms: D002353:Carrier State / Q000097:blood / Q000175:diagnosis*; D005260:Female; D015658:HIV Infections / Q000097:blood / Q000175:diagnosis*; D015497:HIV-1; D006801:Humans; D007958:Leukocyte Count; D007963:Leukocytes, Mononuclear / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D008297:Male