Crystals and structures of cytochrome c oxidases--the end of an arduous road.
Crystal structures of cytochrome c oxidases, one of which is the largest membrane-bound protein complex crystallized to date in a form suitable for X-ray diffraction, have recently been solved. The information from these accomplishments confirms many of the structural properties known from earlier spectroscopic and analytical studies, and provides a basis for understanding the complex mechanisms of electron transfer and proton pumping.
Beinert
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Institute for Enzyme Research, Graduate School, University of Wisconsin-Madison 53705-4098, USA.
D000818:Animals; D018360:Crystallography, X-Ray; D004579:Electron Transport / Q000502:physiology; D003576:Electron Transport Complex IV / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D017494:Proton Pumps / Q000502:physiology
D017494:Proton Pumps; D003576:Electron Transport Complex IV