title: A rare insertion of T226 in exon 1 of CYP2D6 causes a frameshift and is associated with the poor metabolizer phenotype: CYP2D6*15.
authors.affiliation: Institut für Klinische Pharmakologie, Universitätsklinikum Charité der Humboldt-Universitätzn Berlin, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Sachse
authors.forename: J
authors.initials: J
authors.lastname: Brockmöller
authors.forename: S
authors.initials: S
authors.lastname: Bauer
authors.forename: T
authors.initials: T
authors.lastname: Reum
authors.forename: I
authors.initials: I
authors.lastname: Roots
mesh_terms: D000328:Adult; D000483:Alleles; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics* / Q000378:metabolism; D003647:Debrisoquin / Q000493:pharmacokinetics / Q000652:urine; D003915:Dextromethorphan / Q000493:pharmacokinetics / Q000652:urine; D005091:Exons; D016368:Frameshift Mutation; D006801:Humans; D008297:Male; D010641:Phenotype; D011544:Pseudogenes
chemical_list: D003915:Dextromethorphan; D019389:Cytochrome P-450 CYP2D6; D003647:Debrisoquin