[Synthesis of certain derivatives of 5-methoxy-3-[(benzazole-2-yl) thioacetylamino]-2,3-dihydrobenzofuran and research on their antihypertensive activities].
In this study, some 5-methoxy-3-[(benzazole-2-yl)thioacetylamino]-2, 3-dihydrobenzofuran derivatives were synthesized and their structures were elucidated by IR, NMR and microanalyses. The antihypertensive activities of the compounds obtained were investigated.
Turan-Zitouni
G
G
Laboratoire de Pharmacie Chimique, Faculté de Pharmacie, Université d'Anadolu, Eskişehir, Turquie.
Demirayak
S
S
Erol
K
K
Ozdemir
M
M
D000818:Animals; D000959:Antihypertensive Agents / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D001572:Benzofurans / Q000138:chemical synthesis* / Q000494:pharmacology / Q000633:toxicity; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005260:Female; D066298:In Vitro Techniques; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D009131:Muscle, Smooth, Vascular / Q000187:drug effects; D009638:Norepinephrine / Q000037:antagonists & inhibitors / Q000494:pharmacology; D011817:Rabbits
D000959:Antihypertensive Agents; D001572:Benzofurans; D009638:Norepinephrine