The potential role and mechanisms of FeLV vaccine-induced neoplasms.
Vaccine-induced sarcomas are reported to occur in 1 in 10,000 or less cats vaccinated with feline leukemia virus (FeLV) vaccines. The potential of local vaccine site adjuvant-associated inflammation plays in the pathogenesis of these tumors is probably significant. However, it is believed that the feline leukemia antigens contained within these vaccines also play an important role in malignant transformation.
Macy
D W
DW
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Ft. Collins, USA.
D000818:Animals; D002371:Cat Diseases / Q000209:etiology*; D002415:Cats; D005354:Fibrosarcoma / Q000209:etiology / Q000662:veterinary; D005256:Leukemia Virus, Feline / Q000276:immunology*; D009369:Neoplasms / Q000209:etiology / Q000662:veterinary*; D014765:Viral Vaccines / Q000009:adverse effects* / Q000494:pharmacology
D014765:Viral Vaccines