title: Cutaneous and pulmonary infections caused by Mycobacterium vaccae.
abstract: Mycobacterium vaccae is a rapidly growing mycobacterial species that was previously not considered a human pathogen. We report four cases of M. vaccae infection that occurred in the southern United States; one patient had cutaneous disease, and three patients had cavitary lung disease. Two of the three patients with pulmonary disease had a history of exposure to cattle. The conditions of all patients improved with therapy: the cutaneous infection responded to therapy with minocycline and trimethoprim-sulfamethoxazole, and the pulmonary infections responded to therapy with ciprofloxacin.
authors.affiliation: Department of Medical Specialities, University of Texas M. D. Anderson Cancer Center, Houston 77030, USA.
authors.forename: R
authors.initials: R
authors.lastname: Hachem
authors.forename: I
authors.initials: I
authors.lastname: Raad
authors.forename: K V
authors.initials: KV
authors.lastname: Rolston
authors.forename: E
authors.initials: E
authors.lastname: Whimbey
authors.forename: R
authors.initials: R
authors.lastname: Katz
authors.forename: J
authors.initials: J
authors.lastname: Tarrand
authors.forename: H
authors.initials: H
authors.lastname: Libshitz
mesh_terms: D000368:Aged; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002417:Cattle; D002939:Ciprofloxacin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D008911:Minocycline / Q000627:therapeutic use; D009161:Mycobacterium / Q000302:isolation & purification / Q000472:pathogenicity; D009164:Mycobacterium Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D009369:Neoplasms / Q000150:complications; D018410:Pneumonia, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D017192:Skin Diseases, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D008911:Minocycline