Use of adhesion prevention barriers in ovarian surgery, tubalplasty, ectopic pregnancy, endometriosis, adhesiolysis, and myomectomy.
Intraperitoneal barriers reduce adhesion by preventing the formation of fibrin bridges between healing tissues. Although barriers were shown to be safe and effective in all human clinical trials, their use did not eliminate adhesions in all patients. Although barrier methods are the most effective technique for the prevention of adhesion reformation, efficacy of the barriers is limited to surgical situations where the area in question can be covered completely. Acceptance by physicians is constrained by technical difficulties including the need for hemostasis and removal of excess peritoneal fluid as well as concerns regarding fixation techniques and subsequent removal of the barrier.
diZerega
G S
GS
University of Southern California School of Medicine, Department of Obstetrics and Gynecology, Livingston Reproductive Biology Laboratory, Los Angeles 90033, USA.
D000291:Adnexal Diseases / Q000601:surgery*; D002483:Cellulose, Oxidized / Q000627:therapeutic use; D003911:Dextrans / Q000627:therapeutic use; D004715:Endometriosis / Q000601:surgery*; D005260:Female; D006801:Humans; D011138:Polytetrafluoroethylene / Q000627:therapeutic use; D011183:Postoperative Complications / Q000517:prevention & control*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000601:surgery*; D013514:Surgical Procedures, Operative / Q000009:adverse effects*; D000267:Tissue Adhesions / Q000209:etiology / Q000517:prevention & control; D014591:Uterine Diseases / Q000601:surgery*
D002483:Cellulose, Oxidized; D003911:Dextrans; C060002:INTERCEED; D011138:Polytetrafluoroethylene