Bilateral exudative retinal detachment complicating systemic corticosteroid therapy in the presence of renal failure.
OBJECTIVE
We describe an elderly patient with chronic renal failure who developed bilateral exudative retinal detachments after initiation of systemic corticosteroid therapy, followed by prompt resolution of the retinal detachments after the corticosteroids were discontinued.


METHODS
The medical record was examined and reviewed to document the clinical course, treatment, and therapeutic response.


RESULTS
Two weeks after receiving systemic corticosteroids for deteriorating renal failure, the patient had painless bilateral visual loss. Rapid tapering of the corticosteroids concurrent with hemodialysis and subsequent improvement of renal failure resulted in resolution of the exudative retinal detachments. The right eye developed a 360-degree retinal pigment epithelial tear in the macula.


CONCLUSIONS
Exudative retinal detachments may complicate systemic corticosteroid therapy.
Desatnik
H R
HR
Division of Ophthalmology, Cleveland Clinic Eye Institute, Cleveland Clinic Foundation, OH 44195-5024, USA.
Gutman
F A
FA
D000368:Aged; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D005122:Exudates and Transudates; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D011241:Prednisone / Q000009:adverse effects*; D006435:Renal Dialysis; D012163:Retinal Detachment / Q000139:chemically induced* / Q000503:physiopathology; D012167:Retinal Perforations / Q000209:etiology; D014786:Vision Disorders / Q000139:chemically induced / Q000503:physiopathology
D000893:Anti-Inflammatory Agents; D011241:Prednisone