Nodular cutaneous lupus mucinosis: report of a case and review of previously reported cases.
A wide variety of cutaneous manifestations of lupus erythematosus have been reported. Among them, papulonodular eruptions produced by dermal mucin deposition have been recognized as nodular cutaneous lupus mucinosis (NCLM), and many cases have been reported in Japan. A 21-year-old woman with systemic lupus erythematosus (SLE) showed papulonodular eruptions on her back. A skin specimen from the nodule revealed mucin deposition (hyaluronic acid) in the dermis. NCLM should be recognized as a clinical form associated with SLE. The pathogenesis of the mucin deposition in NCLM is still uncertain.
Kano
Y
Y
Department of Dermatology, University School of Medicine, Tokyo, Japan.
Sagawa
Y
Y
Yagita
A
A
Nagashima
M
M
D000328:Adult; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000032:analysis; D008178:Lupus Erythematosus, Cutaneous / Q000473:pathology*; D008180:Lupus Erythematosus, Systemic / Q000473:pathology; D017520:Mucinoses / Q000473:pathology*; D009077:Mucins / Q000032:analysis; D012867:Skin / Q000473:pathology
D009077:Mucins; D006820:Hyaluronic Acid