[Goodpasture's syndrome with negative renal immunofluorescence].
The diagnosis of Goodpasture's syndrome is established by the clinical setting of diffuse alveolar hemorrhage and glomerulonephritis, and the demonstration of circulating or tissue-bound antibasement membrane antibodies. However, cases of Goodpasture's syndrome limited either to the lungs or kidneys have been reported. The absence of immune deposits from renal biopsy specimens of a patient with Goodpasture's syndrome, even with normal renal function, is exceptional. We report here a case of Goodpasture's syndrome characterized by direct immunofluorescence staining of the transbronchial biopsy specimen, and with direct negative immunofluorescence on renal biopsy specimen.
Izquierdo Patrón
M
M
Secciones de Neumología, Nefrología, Hospital General de Albacete.
Haro Estarriol
M
M
Coloma Navarro
R
R
Andrés
E
E
Iñíguez
L
L
D000328:Adult; D019867:Anti-Glomerular Basement Membrane Disease / Q000175:diagnosis*; D005189:False Positive Reactions; D019085:Fluorescent Antibody Technique, Direct; D006801:Humans; D008297:Male