Solution-phase generation of tetraurea libraries.
Libraries of tetraureas tethered to a rigid core have been assembled. This simple, solution-phase methodology generates a defined, anticipated distribution of compounds. These conclusions are supported by synthesizing pure (homo) tetraurea xanthenes and by HPLC analysis of small 'microlibraries'.
Shipps
G W
GW
Department of Chemistry, Massachusetts Institute of Technology, Cambridge 02139, USA.
Spitz
U P
UP
Rebek
J
J
D002851:Chromatography, High Pressure Liquid / Q000379:methods; D012996:Solutions / Q000737:chemistry; D014508:Urea / Q000737:chemistry*; D014966:Xanthenes / Q000138:chemical synthesis / Q000737:chemistry*
D012996:Solutions; D014966:Xanthenes; D014508:Urea