title: A wasp head with a relaxing bite.
abstract: The crystal structure of a 92 kDa fragment of the yeast type II topoisomerase reveals a toroidal structure with a large central cavity that is likely to be involved in the translocation of a DNA duplex during catalysis.
authors.affiliation: Laboratory of Molecular Biophysics, University of Oxford, UK.
authors.forename: D B
authors.initials: DB
authors.lastname: Wigley
mesh_terms: D002384:Catalysis; D018360:Crystallography, X-Ray; D004250:DNA Topoisomerases, Type II / Q000737:chemistry*; D011487:Protein Conformation; D012441:Saccharomyces cerevisiae / Q000201:enzymology
chemical_list: D004250:DNA Topoisomerases, Type II