The action of neurotrophins in the development and plasticity of the visual cortex.
Nerve growth factor (NGF) and the other members of the NGF gene family have been extensively characterized as neurotrophic factors. Recently a modulatory action of these neurotrophic factors on synapse efficacy has emerged. The developing visual system has provided a convenient model to test the role of neurotrophins on neural plasticity in vivo.
Cellerino
A
A
Scuola Normale Superiore and C.N.R., Istituto di Neurofisiologia, Pisa, Italy.
Maffei
L
L
D000818:Animals; D019208:Brain-Derived Neurotrophic Factor / Q000502:physiology; D006801:Humans; D009414:Nerve Growth Factors / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology*; D014793:Visual Cortex / Q000254:growth & development* / Q000502:physiology*
D019208:Brain-Derived Neurotrophic Factor; D009414:Nerve Growth Factors