title: [Prognostic factors in prostatic carcinoma treated with radical radiotherapy: stages A, B, and C].
abstract: Analysis of a series of 118 patients with histological diagnosis of prostate carcinoma, localized stages A2, B and C, treated with external radiotherapy with radical purpose between July 1964 and December 1991. The 5-year cause-specific survival was 69% years and 62% at 10 years. Disease-free survival was 56% and 48% at 5 and 10 years respectively. Local, locoregional and distant relapse-free survivals were 91%, 75% and 65% at 10 years respectively. Several factors characterize each tumour, influencing the therapy failure. In our series, non-differentiated, stage C tumours with pathological LDH levels at diagnosis and treated with AP-PA fields showed decreased survival and greater relapse ratios. Two separate factors influence on distant failure: LDH pathological levels at diagnosis and non-differentiated tumours. External radiotherapy is a therapeutical alternative in localized stages of prostate carcinoma, which offers little morbidity and good tolerance, similar results to those obtained with surgical treatment.
authors.affiliation: Servicio de Oncologia Radioterápica, Clinica Puerta de Hierro, Madrid.
authors.forename: S
authors.initials: S
authors.lastname: Rodríguez Villalba
authors.forename: R
authors.initials: R
authors.lastname: Magallón Sebastián
authors.forename: C
authors.initials: C
authors.lastname: Regueiro Otero
authors.forename: G
authors.initials: G
authors.lastname: Rodríguez Reina
authors.forename: J
authors.initials: J
authors.lastname: Romero Fernández
authors.forename: J
authors.initials: J
authors.lastname: Carballido Rodríguez
authors.forename: A
authors.initials: A
authors.lastname: De la Torre Tomás
authors.forename: G
authors.initials: G
authors.lastname: Aragón de la Cruz
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000401:mortality* / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009367:Neoplasm Staging; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000401:mortality* / Q000473:pathology / Q000532:radiotherapy*; D015996:Survival Rate