Cytogenetic and immunohistochemical evidence that giant cell fibroblastoma is related to dermatofibrosarcoma protuberans.
From cytogenetic and immunohistochemical findings in a primary giant cell fibrosarcoma and its recurrence, it is further demonstrated that a close relationship exists between this tumor and dermatofibrosarcoma protuberans. Both tumors express CD34 and show rearrangements of chromosomes 17 and 22.
Dal Cin
P
P
Center for Human Genetics, University of Leuven, Belgium.
Sciot
R
R
de Wever
I
I
Brock
P
P
Casteels-Van Daele
M
M
Van Damme
B
B
Van Den Berghe
H
H
D018952:Antigens, CD34 / Q000235:genetics; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D002886:Chromosomes, Human, Pair 17; D002892:Chromosomes, Human, Pair 22; D018223:Dermatofibrosarcoma / Q000235:genetics* / Q000378:metabolism; D005260:Female; D005350:Fibroma / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D007621:Karyotyping; D008297:Male; D012008:Recurrence; D014178:Translocation, Genetic
D018952:Antigens, CD34