title: [The role of immunopathological factors in severe forms of insulin-dependent diabetes mellitus].
abstract: Immunogrammes of 31 patients with grave forms of insulindependent diabetes mellitus were reviewed. The illness has been characterized as a systemic immunopathologic process combining autoimmune and infectious-and-allergic components realized by organ and tissue abnormalities; it evolves against the manifest background of allergy of both delayed anl immediate types, impairement of the humoral and cell-mediated immunity function, pathogenetic activity of endogenous proteases, the complement system components and interferon.
authors.forename: V A
authors.initials: VA
authors.lastname: Siplivyĭ
authors.forename: I L
authors.initials: IL
authors.lastname: Dikiĭ
authors.forename: A V
authors.initials: AV
authors.lastname: Beresnev
authors.forename: E P
authors.initials: EP
authors.lastname: Tikhonova
mesh_terms: D000328:Adult; D000917:Antibody Formation; D001327:Autoimmune Diseases / Q000209:etiology / Q000276:immunology / Q000473:pathology; D015551:Autoimmunity; D002908:Chronic Disease; D003922:Diabetes Mellitus, Type 1 / Q000209:etiology / Q000276:immunology* / Q000473:pathology; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D007113:Immunity, Innate; D008297:Male