title: Malignant hypertension in association with primary aldosteronism.
abstract: Primary aldosteronism is associated with low plasma renin levels, whilst malignant phase hypertension is generally associated with raised renin activity. These two conditions are therefore at opposite ends of the renin spectrum, so in theory their co-existence would be unusual. We describe in detail 3 cases of primary hyperaldosteronism from a disease register of 315 cases of malignant hypertension seen in one medical centre over 29 years.
authors.affiliation: University Department of Medicine, City Hospital, Birmingham, UK.
authors.forename: J
authors.initials: J
authors.lastname: Zarifis
authors.forename: G Y
authors.initials: GY
authors.lastname: Lip
authors.forename: B
authors.initials: B
authors.lastname: Leatherdale
authors.forename: G
authors.initials: G
authors.lastname: Beevers
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000150:complications* / Q000378:metabolism / Q000503:physiopathology; D006974:Hypertension, Malignant / Q000150:complications* / Q000378:metabolism / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012083:Renin / Q000378:metabolism
chemical_list: D012083:Renin