Younger age as a bad prognostic factor in patients with carcinoma of the cervix.
OBJECTIVE
To verify the influence of age on the prognosis of cervix carcinoma.


METHODS
Five hundred and sixty eight patients treated for a FIGO stage IB-IVA with radical irradiation in the Centre Hospitalier Universitaire Vaudois of Lausanne were subdivided according to the following age categories: < or = 45, 46-60, 61-69 and >70 years. Taking the 46-60 years age group as the reference, the hazard ratios (HR) of death and corresponding 95% confidence intervals (95% CI) were estimated by means of a Cox multivariate analysis.


RESULTS
The 5-year survival rates were, respectively, 57%, 67%, 60% and 45%. For the youngest women the risk of death was significantly increased (HR = 2.00, 95% CI [1.32-3.00]) and was even more accentuated in advanced stages.


CONCLUSIONS
Age under 45 years is a bad prognostic factor in carcinoma of the cervix.
Delaloye
J F
JF
Departement de Gynecologie et d'Obstetrique, Centre Hospitalier Universitaire, Vaudois, Switzerland.
Pampallona
S
S
Coucke
P A
PA
De Grandi
P
P
D000328:Adult; D000367:Age Factors; D000368:Aged; D002277:Carcinoma / Q000401:mortality* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000401:mortality* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery