Facial nerve paralysis in acute otomastoiditis as presenting symptom of FAB M2, T8;21 leukemic relapse. Case report and review of the literature.
Granulocytic sarcoma (chloroma) is a rare solid, extramedullary tumour composed of immature granulocytes, occurring during granulocytic leukemia. Leukemic involvement of the temporal bone is not uncommon and may present in a variety of ways. Symptomatic facial nerve paralysis is one of these. The authors report a case of facial nerve paralysis as the presenting symptom of leukemic relapse in a 16-year-old white male, affected by acute myelogenous leukemia FAB M2, karyotype 46xy, T8;21.
Almadori
G
G
Department of Otorhinolaryngology-Head and Neck Surgery, Catholic University of the Sacred Heart, Rome, Italy.
Del Ninno
M
M
Cadoni
G
G
Di Mario
A
A
Ottaviani
F
F
D000208:Acute Disease; D000293:Adolescent; D003937:Diagnosis, Differential; D004428:Ear Neoplasms / Q000175:diagnosis / Q000473:pathology; D004432:Ear, Middle / Q000473:pathology; D005154:Facial Nerve / Q000503:physiopathology*; D005158:Facial Paralysis / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D008297:Male; D008417:Mastoiditis / Q000175:diagnosis / Q000209:etiology*; D009361:Neoplasm Invasiveness; D012008:Recurrence; D012509:Sarcoma / Q000175:diagnosis / Q000473:pathology; D013701:Temporal Bone / Q000473:pathology; D014057:Tomography, X-Ray Computed