title: Channels in transporters.
abstract: Recent electrophysiological investigations of plasma membrane neurotransmitter transporters have shown that carriers can function in ways similar to ion channels. The results of these studies reveal underlying mechanisms not encompassed by classic carrier models and support an emerging view that transporter-mediated ionic currents may contribute to signaling in the nervous system.
authors.affiliation: Howard Hughes Medical Institute and Vollum Institute, Oregon Health Sciences University, Portland, Oregon 97201, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Sonders
authors.forename: S G
authors.initials: SG
authors.lastname: Amara
mesh_terms: D026905:Amino Acid Transport Systems; D000818:Animals; D001679:Biogenic Amines / Q000378:metabolism; D001692:Biological Transport; D002352:Carrier Proteins / Q000737:chemistry / Q000378:metabolism / Q000502:physiology*; D004553:Electric Conductivity; D004594:Electrophysiology; D006801:Humans; D007473:Ion Channels / Q000502:physiology*; D007477:Ions; D008433:Mathematics
chemical_list: D026905:Amino Acid Transport Systems; D001679:Biogenic Amines; D002352:Carrier Proteins; D007473:Ion Channels; D007477:Ions