title: The two-headed antigen. B-cell co-receptors.
abstract: Lymphocytes often recognize antigens using not only their antigen receptors but also 'co-receptors' that bind other molecules associated with the antigen; the co-receptors then modulate the response to antigen. This concept has been used to make chimeric antigens that are extremely potent inducers of antibody responses.
authors.affiliation: Department of Microbiology, University of California, San Francisco, California 94143-0552, USA.
authors.forename: A L
authors.initials: AL
authors.lastname: DeFranco
mesh_terms: D000917:Antibody Formation; D006801:Humans; D011947:Receptors, Antigen, B-Cell / Q000276:immunology*
chemical_list: D011947:Receptors, Antigen, B-Cell