[Changes in the immunocompetent cell system of the peripheral blood in HIV carriage].
HIV-carriage is characterized by hematological signs such as normocytosis of the general leucocyte count and deviations within normal range of values for myeloid series cells (neutrophiles, eosinophiles, basophiles). A peculiar hematological sign seen in HIV-infection is a finding of a raised content of cellular elements of mononuclear type on a hemogramme of peripheral blood and consistent decrease in the level of small T-lymphocytes against the background of substantial growth of suppressor-killer populations (large lymphocytes and lymphocyte-like mononuclears) as evidenced by a mononucleorogramme of peripheral blood, which fact provide a mechanism of antiviral protection at early stages of HIV-infection. Such changes in hemogrammes of peripheral blood, consistently found in all virus carriers, may be used in clinical settings as an early diagnostic sign of HIV-infection.
Karabanov
V R
VR
Markov
I S
IS
Marchenko
N E
NE
D002353:Carrier State / Q000097:blood / Q000175:diagnosis*; D005260:Female; D015658:HIV Infections / Q000097:blood / Q000175:diagnosis*; D015497:HIV-1; D006801:Humans; D007958:Leukocyte Count; D007963:Leukocytes, Mononuclear / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology*; D008297:Male