Serological study of type A Indian foot-and-mouth disease virus isolates.
The antigenic relationship of sixty type A foot-and-mouth disease (FMD) viruses isolated between 1968 and 1993 has been determined with reference to a post-vaccinal bovine serum produced against type A IND 17/82. A micro-neutralization test and ELISA were used to compare isolates. Analysis of the results indicated that there was a positive correlation between the data from the two methods. The study indicated that type A IND 17/82 had a broad immunogenic spectrum and could be considered as a candidate vaccine strain for incorporation in FMD vaccines in India.
Meer Azad
H
H
Indian Immunologicals, Gachibowli, Hyderabad, India.
Srinivasan
V A
VA
Crowther
J R
JR
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D000956:Antigens, Viral / Q000276:immunology*; D005537:Aphthovirus / Q000276:immunology* / Q000302:isolation & purification; D002417:Cattle; D002460:Cell Line; D006224:Cricetinae; D006168:Guinea Pigs; D007194:India; D011817:Rabbits
D000914:Antibodies, Viral; D000956:Antigens, Viral