Evaluation of sulfa drugs against recombinant Pneumocystis carinii dihydropteroate synthetase and in vivo.
Hong
Y L
YL
Dept. of Epidemiology, Univ. of Michigan, Ann Arbor, USA.
Hossler
P
P
Bartlett
M
M
Queener
S
S
Smith
J
J
Meshnick
S
S
D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D004094:Dihydropteroate Synthase / Q000037:antagonists & inhibitors*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005492:Folic Acid / Q000096:biosynthesis; D051379:Mice; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D011010:Pneumocystis / Q000187:drug effects* / Q000378:metabolism; D051381:Rats; D013421:Sulfamethoxypyridazine / Q000494:pharmacology; D013424:Sulfanilamides / Q000737:chemistry / Q000494:pharmacology*
D000935:Antifungal Agents; D004791:Enzyme Inhibitors; D013424:Sulfanilamides; D005492:Folic Acid; D004094:Dihydropteroate Synthase; D013421:Sulfamethoxypyridazine