Revascularization of the bronchial arteries in lung transplantation: an overview.
Development of the surgical technique has minimized the incidence of airway problems associated with single as well as sequential bilateral lung transplantation. Although early results are good, long-term results remain unsatisfactory. The main problems after lung transplantation are pulmonary infections and the bronchiolitis obliterans syndrome. The bronchiolitis obliterans syndrome is usually considered to be chronic rejection, but a multifactorial genesis including airway ischemia has been suggested. We reviewed the literature relevant to direct bronchial artery revascularization during lung transplantation. Although information is limited, there are good reasons to believe that reestablishment of the dual blood supply to the transplanted lung is beneficial not only for healing of the airway anastomoses, but also for the airway and the lung responses to pathologic conditions. In small series, methods of bronchial artery revascularization have proved successful and have been associated with good early results. We believe it is justified to test the impact of direct bronchial artery revascularization on outcome after lung transplantation in large clinical series.
Nørgaard
M A
MA
Department of Cardiovascular Surgery, Copenhagen University Hospital, Denmark.
Olsen
P S
PS
Svendsen
U G
UG
Pettersson
G
G
D000792:Angiography; D000818:Animals; D001981:Bronchial Arteries / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D008168:Lung / Q000098:blood supply; D016040:Lung Transplantation / Q000379:methods*