title: Knockout mice and dirty drugs. Drug addiction.
abstract: Recent studies with knockout mice implicate the dopamine transporter as the target of the locomotor effects of the addictive psychomotor drugs cocaine and amphetamine; studies of reward in these animals are eagerly awaited.
authors.affiliation: Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse Addiction Research Center, PO Box 5180, Baltimore, Maryland 21224, USA.
authors.forename: G R
authors.initials: GR
authors.lastname: Uhl
authors.forename: D J
authors.initials: DJ
authors.lastname: Vandenbergh
authors.forename: L L
authors.initials: LL
authors.lastname: Miner
mesh_terms: D000661:Amphetamine / Q000494:pharmacology*; D000818:Animals; D002352:Carrier Proteins / Q000187:drug effects* / Q000235:genetics / Q000378:metabolism; D003042:Cocaine / Q000494:pharmacology*; D004298:Dopamine / Q000378:metabolism; D050483:Dopamine Plasma Membrane Transport Proteins; D008124:Locomotion / Q000187:drug effects; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D051379:Mice; D018345:Mice, Knockout; D009419:Nerve Tissue Proteins; D009293:Opioid-Related Disorders / Q000235:genetics* / Q000378:metabolism
chemical_list: D002352:Carrier Proteins; D050483:Dopamine Plasma Membrane Transport Proteins; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; D000661:Amphetamine; D003042:Cocaine; D004298:Dopamine