title: The treatment of recurrence following fast neutron therapy for head and neck malignancy.
abstract: Twenty-eight patients received fast neutron therapy for head and neck malignancy. Of these, seven had no recurrence, 13 had a recurrence at the primary site, five had a recurrence in the neck and three had a recurrence in the neck and at the primary site. Treatment of a primary site recurrence was difficult with seven of the eight patients submitted for major surgical resection developing serious complications. Of the six patients developing a fistula four required flap repair. The tumour specific 5-year survival for the whole group of 28 patients was 29%. The surgical treatment of locoregional recurrence following fast neutron therapy is fraught with problems and some type of flap repair is usually necessary.
authors.affiliation: Department of Otolarynology, Royal Liverpool University Hospital, UK.
authors.forename: S
authors.initials: S
authors.lastname: Asgarali
authors.forename: R D
authors.initials: RD
authors.lastname: Errington
authors.forename: A S
authors.initials: AS
authors.lastname: Jones
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D009502:Neutrons / Q000627:therapeutic use*; D011829:Radiation Dosage; D016896:Treatment Outcome