title: Long-term results of reconstructions of the left anterior descending coronary artery in diffuse atherosclerotic lesions.
abstract: One hundred twenty patients who had diffuse atherosclerotic lesions necessitating reconstruction of the left anterior descending artery with or without open endarterectomy and coronary artery bypass grafting were investigated retrospectively and compared with 130 patients who underwent conventional bypass grafting in the same time frame.
  
  
  METHODS
  Sixty-one endarterectomies were performed with long arteriotomies (group I) and 59 patch reconstructions were placed over stenosing plaques without an endarterectomy (group II). Patients having only conventional coronary bypass constituted group III.
  
  
  RESULTS
  Hospital mortalities were 6.5%, 5.1%, and 1.5% in group I, group II, and group III, respectively (p = not significant). Five patients in group I (8.1%), six in group II (10.1%), and two in group III (1.5%) had perioperative myocardial infarction (group II vs group III, p = 0.016). Angiographic restudy of grafts to the left anterior descending system revealed a patency rate of 81.5% in group I, 79.1% in group II, and 94.4% in group III patients after mean periods of 6.3, 5.7, and 6.1 years, respectively (p = not significant). Actuarial survivals at 7 years were 94% +/- 5.0%, 74.8% +/- 16%, and 90.9% +/- 7.4% in groups I, II, and III, respectively (group I vs group II, p = 0.007; group II vs group III, p = 0.008). Freedom from recurrent angina at 7 years was 42.7% +/- 15.6% in group I, 33.5% +/- 19% in group II, and 71.9% +/- 14.2% in group III (group I vs group III, p = 0.03; group II vs group III, p = 0.0001). Thirty-four percent of patients in group I, 24% in group II, and 60.4% in group III were working actively in the late postoperative period (p = 0.0001).
  
  
  CONCLUSIONS
  Extended revascularizations of the left anterior descending coronary artery increase surgical risk, although not to a statistically significant degree, and should be performed only of necessity. However, once needed, revascularization is a lifesaving procedure with acceptable early and long-term results.
authors.affiliation: Department of Cardiovascular Surgery, Türkiye Yüksek Ihtisas Hospital, Ankara.
authors.forename: O
authors.initials: O
authors.lastname: Taşdemir
authors.forename: U
authors.initials: U
authors.lastname: Kiziltepe
authors.forename: H Y
authors.initials: HY
authors.lastname: Karagöz
authors.forename: B
authors.initials: B
authors.lastname: Yamak
authors.forename: S
authors.initials: S
authors.lastname: Korkmaz
authors.forename: K
authors.initials: K
authors.lastname: Bayazit
mesh_terms: D000206:Actuarial Analysis; D000787:Angina Pectoris / Q000628:therapy; D017023:Coronary Angiography; D001026:Coronary Artery Bypass / Q000009:adverse effects; D003324:Coronary Artery Disease / Q000601:surgery*; D003327:Coronary Disease / Q000601:surgery; D003331:Coronary Vessels / Q000601:surgery*; D018572:Disease-Free Survival; D004691:Endarterectomy / Q000009:adverse effects; D005260:Female; D006083:Graft Occlusion, Vascular / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology; D011183:Postoperative Complications; D012008:Recurrence; D012189:Retrospective Studies; D015996:Survival Rate; D014654:Vascular Patency; D014937:Work