title: Genetic barriers among bacteria.
abstract: Barriers to chromosomal gene transfer between bacterial species control their genetic isolation. These barriers, such as different microhabitats, the host ranges of genetic exchange vectors and restriction-modification systems, limit gene exchange, but the major limitation is genomic sequence divergence. The mismatch-repair system inhibits interspecies recombination, the inducible SOS system stimulates interspecies recombination, while natural selection determines the effective recombination frequencies.
authors.affiliation: Laboratoire de Mutagenese, Institut Jacques Monod, Paris, France. matic@ccr.jussieu.fr
authors.forename: I
authors.initials: I
authors.lastname: Matic
authors.forename: F
authors.initials: F
authors.lastname: Taddei
authors.forename: M
authors.initials: M
authors.lastname: Radman
mesh_terms: D001419:Bacteria / Q000235:genetics*; D003227:Conjugation, Genetic; D015280:DNA Restriction-Modification Enzymes / Q000235:genetics; D018014:Gene Transfer Techniques; D011995:Recombination, Genetic; D013014:SOS Response, Genetics; D012641:Selection, Genetic; D013045:Species Specificity; D014161:Transduction, Genetic; D014170:Transformation, Genetic
chemical_list: D015280:DNA Restriction-Modification Enzymes