title: Experimental Aujeszky's disease in blue foxes (Alopex lagopus).
abstract: Blue foxes were inoculated orally with Aujeszky's disease virus. Several foxes were killed at the onset of clinical signs and other animals spontaneously died. The incubation period ranged from 3 to 6 days and was followed by a short illness characterized by anorexia, depression and coma. At autopsy, no specific gross findings were observed. Microscopically, lesions included a non-suppurative meningoencephalitis with neuronal necrosis, gliosis, neuronophagia and mononuclear cell cuffing. Viral antigen was detected by immunoperoxidase technique.
authors.affiliation: Laboratory of Veterinary Pathology, School of Veterinary Medicine, Lugo, Spain.
authors.forename: M I
authors.initials: MI
authors.lastname: Quiroga
authors.forename: S
authors.initials: S
authors.lastname: Vázquez
authors.forename: M
authors.initials: M
authors.lastname: López-Peña
authors.forename: F
authors.initials: F
authors.lastname: Guerrero
authors.forename: J M
authors.initials: JM
authors.lastname: Nieto
mesh_terms: D000818:Animals; D000855:Anorexia / Q000662:veterinary; D000956:Antigens, Viral / Q000032:analysis; D003128:Coma / Q000662:veterinary; D003863:Depression; D005589:Foxes; D011558:Herpesvirus 1, Suid / Q000302:isolation & purification; D007124:Immunoenzyme Techniques / Q000662:veterinary; D008526:Medulla Oblongata / Q000473:pathology; D011149:Pons / Q000473:pathology; D011557:Pseudorabies / Q000473:pathology*
chemical_list: D000956:Antigens, Viral