Differentiation of Mycobacterium genavense and Mycobacterium simiae by automated mycolic acid analysis with high-performance liquid chromatography.
Mycobacterium genavense, a fastidious opportunist in patients with AIDS, cannot be identified by conventional biochemical methods. Computerized mycolic acid analysis by high-performance liquid chromatography offers an alternative that distinguishes the mycolic acid profile of M. genavense from those of all other organisms in the database developed at the Centers for Disease Control and Prevention.
Ritter
D
D
Department of Laboratory Medicine, University of Washington Medical Center, Seattle, USA.
Carlson
L D
LD
Logan
B K
BK
Ramos
L S
LS
Kilburn
J O
JO
Coyle
M B
MB
D015373:Bacterial Typing Techniques; D002851:Chromatography, High Pressure Liquid; D016000:Cluster Analysis; D003198:Computer Simulation; D006801:Humans; D008956:Models, Chemical; D009161:Mycobacterium / Q000737:chemistry* / Q000145:classification*; D009164:Mycobacterium Infections / Q000382:microbiology; D009171:Mycolic Acids / Q000032:analysis*; D013045:Species Specificity
D009171:Mycolic Acids