pH6 antigen (PsaA protein) of Yersinia pestis, a novel bacterial Fc-receptor.
It was found that recombinant pH6 antigen (rPsaA protein) forming virulence-associated fimbriae on the surface of Yersinia pestis at pH 6.7 in host macrophage phagolysosomes or extracellularly in abscesses such as buboes, is a novel bacterial Fc-receptor. rPsaA protein displays reactivity with human IgG1, IgG2 and IgG3 subclasses but does not react with rabbit, mouse and sheep IgG.
Zav'yalov
V P
VP
Institute of Engineering Immunology, Chekhov District, Moscow Region, Russia.
Abramov
V M
VM
Cherepanov
P G
PG
Spirina
G V
GV
Chernovskaya
T V
TV
Vasiliev
A M
AM
Zav'yalova
G A
GA
D000595:Amino Acid Sequence; D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology; D001426:Bacterial Proteins / Q000235:genetics* / Q000276:immunology*; D003001:Cloning, Molecular; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D051379:Mice; D008969:Molecular Sequence Data; D045322:Photosynthetic Reaction Center Complex Proteins / Q000235:genetics* / Q000276:immunology*; D045331:Photosystem I Protein Complex; D010957:Plasmids; D011817:Rabbits; D011961:Receptors, Fc / Q000276:immunology*; D011994:Recombinant Proteins / Q000276:immunology; D012756:Sheep; D015010:Yersinia pestis / Q000235:genetics* / Q000472:pathogenicity*
D000942:Antigens, Bacterial; D001426:Bacterial Proteins; D007074:Immunoglobulin G; C073973:PSI-A protein, Synechococcus; D045322:Photosynthetic Reaction Center Complex Proteins; D045331:Photosystem I Protein Complex; D011961:Receptors, Fc; D011994:Recombinant Proteins