title: Solution-phase generation of tetraurea libraries.
abstract: Libraries of tetraureas tethered to a rigid core have been assembled. This simple, solution-phase methodology generates a defined, anticipated distribution of compounds. These conclusions are supported by synthesizing pure (homo) tetraurea xanthenes and by HPLC analysis of small 'microlibraries'.
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge 02139, USA.
authors.forename: G W
authors.initials: GW
authors.lastname: Shipps
authors.forename: U P
authors.initials: UP
authors.lastname: Spitz
authors.forename: J
authors.initials: J
authors.lastname: Rebek
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D012996:Solutions / Q000737:chemistry; D014508:Urea / Q000737:chemistry*; D014966:Xanthenes / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: D012996:Solutions; D014966:Xanthenes; D014508:Urea