title: Small cell undifferentiated carcinoma of the colon associated with hepatocellular carcinoma in an immunodeficient patient.
abstract: Small cell undifferentiated carcinoma (oat cell carcinoma) is a malignant epithelial neoplasm with neuroendocrine features. It can appear as a primary tumor in many organs besides the lung, including the colon. We report a case of primary small cell undifferentiated carcinoma of the left colon with omental metastases in a 23-year-old man with a history of X-linked hyper-IgM syndrome. The patient had a simultaneous primary hepatocellular carcinoma. A literature review of this rare colonic malignancy is presented together with a discussion of the possible relationship of this tumor with hepatic malignancy and immunodeficiency.
authors.affiliation: Department of Pediatrics, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
authors.forename: H J
authors.initials: HJ
authors.lastname: Zirkin
authors.forename: J
authors.initials: J
authors.lastname: Levy
authors.forename: L
authors.initials: L
authors.lastname: Katchko
mesh_terms: D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D018288:Carcinoma, Small Cell / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D003110:Colonic Neoplasms / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D005500:Follow-Up Studies; D006801:Humans; D006942:Hypergammaglobulinemia / Q000473:pathology; D007075:Immunoglobulin M; D007153:Immunologic Deficiency Syndromes / Q000473:pathology*; D008113:Liver Neoplasms / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery / Q000648:ultrastructure; D009852:Omentum
chemical_list: D007075:Immunoglobulin M