title: Controller for an axial flow blood pump.
abstract: A rotary blood pump inherently provides only one noninvasive "observable" parameter (motor current) and allows for only one "controllable" parameter (pump speed.) To maintain the systemic circulation properly, the pump seed must be controlled to sustain appropriate outlet flows and perfusion pressure while preventing pulmonary damage caused by extremes in preload. Steady-state data were collected at repeated intervals during chronic trials of the Nimbus AxiPump (Nimbus, Inc., Rancho Cordova, California, U.S.A.) in sheep (n = 7) and calves (n = 12). For each data set, the pump speed was increased at increments of 500 rpm until left ventricular and left atrial emptying was observed by left atrial pressure diminishing to zero. The effect of decreasing preload was evaluated perioperatively by inferior vena cava occlusion at a constant pump speed. Fourier analysis established a relationship between changes in the pump preload and the power spectra of the pump current waveform. Based on these results, a control method was devised to avoid ventricular collapse and maintain the preload within a physiologic range. The objective of this controller is the minimization of the second and third harmonic of the periodic current waveform. This method is intended to provide a noninvasive regulation of the pump by eliminating the need for extraneous transducers.
authors.affiliation: University of Pittsburgh, Artificial, Heart and Lung Program, School of Medicine, Pennsylvania, USA.
authors.forename: H
authors.initials: H
authors.lastname: Konishi
authors.forename: J F
authors.initials: JF
authors.lastname: Antaki
authors.forename: D V
authors.initials: DV
authors.lastname: Amin
authors.forename: J R
authors.initials: JR
authors.lastname: Boston
authors.forename: J P
authors.initials: JP
authors.lastname: Kerrigan
authors.forename: W A
authors.initials: WA
authors.lastname: Mandarino
authors.forename: P
authors.initials: P
authors.lastname: Litwak
authors.forename: K
authors.initials: K
authors.lastname: Yamazaki
authors.forename: M
authors.initials: M
authors.lastname: Macha
authors.forename: K C
authors.initials: KC
authors.lastname: Butler
authors.forename: H S
authors.initials: HS
authors.lastname: Borovetz
authors.forename: R L
authors.initials: RL
authors.lastname: Kormos
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D004867:Equipment Design / Q000639:trends; D006353:Heart-Assist Devices / Q000592:standards* / Q000639:trends; D006439:Hemodynamics / Q000502:physiology*; D011786:Quality Control; D012756:Sheep; D014463:Ultrasonography