Molecular cytogenetics and its applications to soft tissue tumor analysis.
Cytogenetic analyses have demonstrated the association of specific chromosomal changes with particular types of soft tissue tumors. This work describes the molecular cytogenetic approaches to genetic analysis of these tumors. It illustrates how molecular cytogenetics may provide a rapid and sensitive method of diagnosis and can contribute to identify specific genes implied in the aetiology of soft tissue tumors.
D'Amato
L
L
Division of Anatomical Pathology and Cytology, Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan, Italy.
D000818:Animals; D002869:Chromosome Aberrations / Q000175:diagnosis* / Q000235:genetics*; D025063:Chromosome Disorders; D003582:Cytogenetics; D017931:DNA Primers; D015342:DNA Probes; D004273:DNA, Neoplasm / Q000235:genetics; D003937:Diagnosis, Differential; D016678:Genome; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007553:Isotope Labeling; D007621:Karyotyping; D009693:Nucleic Acid Hybridization; D012983:Soft Tissue Neoplasms / Q000175:diagnosis* / Q000235:genetics*; D014178:Translocation, Genetic
D017931:DNA Primers; D015342:DNA Probes; D004273:DNA, Neoplasm