ATP receptors in sickness, pain and death.
Extracellular ATP elicits biological responses ranging from cell death to synaptic transmission. Recent gene-cloning efforts have uncovered a family of cell-surface ATP receptors, which are potential targets for the development of novel drugs to treat airway and cardiovascular diseases, inflammation and pain.
Brake
A
A
Department of Cellular and Molecular Pharmacology, University of California, San Francisco, CA 94143, USA.
Schumacher
M
M
Julius
D
D
D000255:Adenosine Triphosphate / Q000502:physiology; D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D003001:Cloning, Molecular; D007249:Inflammation / Q000188:drug therapy; D010146:Pain / Q000188:drug therapy / Q000503:physiopathology*; D018048:Receptors, Purinergic P2 / Q000235:genetics / Q000502:physiology*
D018048:Receptors, Purinergic P2; D000255:Adenosine Triphosphate