title: Chiral resolution of the dansyl derivative of 2-methyltaurine by capillary electrophoresis.
abstract: A cyclodextrin-modified micellar capillary electrophoretic method was developed for the chiral separation of 2-methyltaurine. The racemic mixture was separated after derivatization with dansyl chloride. The enantiomeric separation of the dansyl derivative was done using electrolyte solutions containing beta-cyclodextrin (beta-CD) or different ratios of beta- and gamma-CD. The mixture of beta- and gamma-CD optimally resolved the compound studied.
authors.affiliation: Dipartimento di Scienze Farmaceutiche, Università di Modena, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Anselmi
authors.forename: D
authors.initials: D
authors.lastname: Braghiroli
authors.forename: M
authors.initials: M
authors.lastname: Di Bella
authors.forename: M G
authors.initials: MG
authors.lastname: Schmid
authors.forename: R
authors.initials: R
authors.lastname: Wintersteiger
authors.forename: G
authors.initials: G
authors.lastname: Gübitz
mesh_terms: D003505:Cyclodextrins / Q000737:chemistry*; D003619:Dansyl Compounds / Q000737:chemistry*; D004573:Electrolytes / Q000737:chemistry; D019075:Electrophoresis, Capillary / Q000379:methods*; D008823:Micelles; D012967:Sodium Dodecyl Sulfate / Q000737:chemistry; D013237:Stereoisomerism; D013654:Taurine / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000302:isolation & purification*
chemical_list: D003505:Cyclodextrins; D003619:Dansyl Compounds; D004573:Electrolytes; D008823:Micelles; D013654:Taurine; D012967:Sodium Dodecyl Sulfate; C103438:2-methyltaurine; C029038:dansyl chloride