Solitary nodule of the thyroid and the role of fine needle aspiration cytology in diagnosis.
In this study the pre-operative diagnostic procedures carried out on 100 patients with clinically solitary nodule of the thyroid experienced over a period of one year with special emphasis on the usefulness of fine needle aspiration biopsy cytology (FNAC) was evaluated retrospectively. All of the 100 patients underwent operation except 2 patients with FNAC diagnosis of Hashimoto's thyroiditis and 7 patients with FNAC diagnosis of colloid goitre. Histopathological study of surgically resected specimens in 91 patients revealed 67 adenomas, one subacute thyroiditis, 3 Hashimoto's thyroiditis, 8 follicular carcinomas, 11 papillary carcinomas and one medullary carcinoma. FNAC tallied in 95% of cases. It was false positive in 2 cases (one case of subacute thyroiditis and one case of Hashimoto's thyroiditis), false negative in one case (a case of follicular carcinoma) and non-diagnostic in 2 cases (2 cases of Hashimoto's thyroiditis).
Dorairajan
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Madras Institute of Endocrinology and Research Centre, Padmini Hospital.
Jayashree
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N
D000293:Adolescent; D000328:Adult; D001707:Biopsy, Needle / Q000379:methods; D002648:Child; D005188:False Negative Reactions; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D016606:Thyroid Nodule / Q000473:pathology* / Q000601:surgery