Activation of toxic chemicals by cytochrome P450 enzymes: regio- and stereoselective oxidation of aflatoxin B1.
Guengerich
F P
FP
Department of Biochemistry and Center in Molecular Toxicology, University College and Middlesex School of Medicine, London, United Kingdom.
Ueng
Y F
YF
Kim
B R
BR
Langouet
S
S
Coles
B
B
Iyer
R S
RS
Thier
R
R
Harris
T M
TM
Shimada
T
T
Yamazaki
H
H
Ketterer
B
B
Guillouzo
A
A
D016604:Aflatoxin B1 / Q000378:metabolism* / Q000633:toxicity; D000818:Animals; D001711:Biotransformation; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D006801:Humans; D009153:Mutagens / Q000378:metabolism* / Q000633:toxicity; D010084:Oxidation-Reduction
D009153:Mutagens; D003577:Cytochrome P-450 Enzyme System; D016604:Aflatoxin B1