title: The clinical spectrum of Henoch-Schönlein purpura in infants and young children.
abstract: Henoch-Schönlein purpura is a common cause of childhood vasculitis. The rarity of the disease under 2 years of age has been the subject of few reports. We present the clinical spectrum of Henoch-Schönlein purpura in 12 children younger than 2 years of age at presentation. The median age at presentation was 11 months. The purpuric skin rash was present in all patients and involved the face in 10 of them. While oedema was a prominent feature in all of our patients only one third had involvement of the kidneys, gastro-intestinal tract or joints. All patients recovered completely after a mean duration of follow up of 10.6 months (range 2-39 months).
  
  
  CONCLUSIONS
  Henoch-Schönlein purpura under the age of 2 years is characterized clinically by oedema and a purpuric skin rash which frequently affects the face. Involvement of the joints, kidneys and gastro-intestinal tract is uncommon and the prognosis is excellent. The clinical spectrum in this age group is a continuation with that of Henoch-Schönlein purpura in older children suggesting a nosological entity.
authors.affiliation: Department of Paediatrics, Jordan University of Science and Technology, Irbid.
authors.forename: M
authors.initials: M
authors.lastname: Al-Sheyyab
authors.forename: H
authors.initials: H
authors.lastname: El-Shanti
authors.forename: S
authors.initials: S
authors.lastname: Ajlouni
authors.forename: D
authors.initials: D
authors.lastname: Sawalha
authors.forename: A
authors.initials: A
authors.lastname: Daoud
mesh_terms: D017668:Age of Onset; D002675:Child, Preschool; D004487:Edema / Q000209:etiology; D005148:Facial Dermatoses / Q000209:etiology; D005260:Female; D005767:Gastrointestinal Diseases / Q000209:etiology; D006801:Humans; D011695:IgA Vasculitis / Q000150:complications / Q000453:epidemiology; D007223:Infant; D007592:Joint Diseases / Q000209:etiology; D007597:Jordan; D007674:Kidney Diseases / Q000209:etiology; D008297:Male; D011379:Prognosis; D014581:Urticaria / Q000209:etiology