title: The mechanism of coupling chemical and physical reactions by the calcium ATPase of sarcoplasmic reticulum and other coupled vectorial systems.
abstract: The coupling of the chemical reaction of ATP hydrolysis to the transport of calcium from the cytoplasm into the lumen of sarcoplasmic reticulum vesicles can be defined by a set of rules that define alternating changes in the specificities of the enzyme for catalysis of chemical and physical reactions.
authors.affiliation: Graduate Department of Biochemistry, Brandeis University, Waltham, Massachusetts 02254-9110, USA.
authors.forename: W P
authors.initials: WP
authors.lastname: Jencks
mesh_terms: D000818:Animals; D000252:Calcium-Transporting ATPases / Q000378:metabolism*; D006801:Humans; D006868:Hydrolysis; D017136:Ion Transport; D012519:Sarcoplasmic Reticulum / Q000378:metabolism*
chemical_list: D000252:Calcium-Transporting ATPases