title: [Serum neopterin in Behçet's disease].
abstract: Neopterin radioimmunoassay measurements (Henning, Berlin) were conducted in 26 male and 12 female patients (mean age 32 +/- 8.01) with Behcet's disease (BD) and healthy controls. In BD patients mean serum neopterin concentrations were significantly higher than in the controls (8.7 +/- 4.1 nmol/l against 5.0 +/- 1.9 nmol/l, respectively). Neopterin levels were higher in patients with positive pathergy test than in negative subjects (p<0.05). There was a significant correlation between neopterin and CRP (rs=0.42. p<0.02). The findings indicate that cellular immunity in BD patients is activated.
authors.forename: M Iu
authors.initials: MIu
authors.lastname: Samsonov
authors.forename: T B
authors.initials: TB
authors.lastname: Prokaeva
authors.forename: V
authors.initials: V
authors.lastname: Madanat
authors.forename: Z S
authors.initials: ZS
authors.lastname: Alekberova
authors.forename: E L
authors.initials: EL
authors.lastname: Nasonov
authors.forename: D
authors.initials: D
authors.lastname: Fuks
authors.forename: Kh
authors.initials: Kh
authors.lastname: Vakhter
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000097:blood*; D001708:Biopterins / Q000031:analogs & derivatives* / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D019798:Neopterin; D011863:Radioimmunoassay
chemical_list: D001708:Biopterins; D019798:Neopterin; D002097:C-Reactive Protein