[Chromatographic support to remove solvent/detergent mixture utilized as viral attenuation agent].
A new method involving a special sorbent designed to specifically capture virus inactivating solvent-detergent mixtures is described. Its specificity allows the adsorption of these undesirable chemicals with a high capacity so as to treat large amounts of inactivated biological fluids in small-sized columns. Typically, the volume of sorbent that can be used repeatedly is between one-fourth to one-tenth of the sample volume to be treated. Cleaning and sanitization can be done classically while strong oxidizing agents can also be used to sterilize the sorbent.
Guerrier
L
L
BioSepra SA, Villeneuve-la-Garenne, France.
Flayeux
I
I
Boschetti
E
E
D000998:Antiviral Agents / Q000737:chemistry*; D002845:Chromatography / Q000379:methods*; D003902:Detergents / Q000008:administration & dosage / Q000302:isolation & purification* / Q000494:pharmacology; D004338:Drug Combinations; D066298:In Vitro Techniques; D012997:Solvents / Q000008:administration & dosage / Q000302:isolation & purification* / Q000494:pharmacology
D000998:Antiviral Agents; D003902:Detergents; D004338:Drug Combinations; D012997:Solvents