Signals and susceptibility to programmed death in b cells.
Programmed death in B cells is a highly regulated process. During the past year it has become increasingly apparent that specific receptor signals influence B cell apoptosis in distinct ways as a function of developmental stage and/or apoptotic trigger. Studies making use of opposing signals for programmed death have begun to reveal molecular correlates of sensitivity and resistance to apoptosis.
Rothstein
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TL
Boston University Medical Center Hospital, MA 02118, USA. trothstein@med-med1.bu.edu
D000818:Animals; D017209:Apoptosis / Q000276:immunology*; D001402:B-Lymphocytes / Q000276:immunology*; D006706:Homeostasis / Q000276:immunology; D006801:Humans; D015398:Signal Transduction / Q000276:immunology*