title: In situ absorption of aflatoxins in rat small intestine.
abstract: To evaluate the rate at which the four main aflatoxins (aflatoxins B1, B2, G1 and G2) are able to cross the luminal membrane of the rat small intestine, a study about intestinal absorption kinetics of these mycotoxins has been made. In situ results obtained showed that the absorption of aflatoxins in rat small intestine is a very fast process that follows first-order kinetics, with an absorption rate constant (ka) of 5.84 +/- 0.05 (aflatoxin B1), 4.06 +/- 0.09 (aflatoxin B2), 2.09 +/- 0.03 (aflatoxin G1) and 1.58 +/- 0.04 (aflatoxin G2) h-1, respectively.
authors.affiliation: Department of Food Technology, University of Lleida, UdL-IRTA Centre R+D, Spain.
authors.forename: A J
authors.initials: AJ
authors.lastname: Ramos
authors.forename: E
authors.initials: E
authors.lastname: Hernández
mesh_terms: D000042:Absorption; D000348:Aflatoxins / Q000493:pharmacokinetics*; D000818:Animals; D007421:Intestine, Small / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000348:Aflatoxins