title: Cleaning up our own backyard: developing new catabolic pathways to degrade pollutants.
abstract: Microbial-based strategies for pollution control require metabolic pathways by which man-made compounds may be degraded. Recombination-based mutagenesis and selection procedures may be able to mimic the evolution of catabolic pathways and generate enzymes with novel specificities.
authors.affiliation: Affymax Research Institute, Palo Alto, CA 94305, USA.
authors.forename: J
authors.initials: J
authors.lastname: Minshull
mesh_terms: D001673:Biodegradation, Environmental; D002384:Catalysis; D004785:Environmental Pollutants / Q000378:metabolism*; D004798:Enzymes / Q000096:biosynthesis* / Q000235:genetics*; D016296:Mutagenesis; D015202:Protein Engineering
chemical_list: D004785:Environmental Pollutants; D004798:Enzymes