Epstein-Barr virus--associated acute autonomic neuropathy.
A 44-year-old man developed blurry vision, photosensitivity, orthostasis, constipation, and acrodysesthesias after a febrile illness. The neurologic examination and ancillary studies were consistent with a dysautonomic small fiber neuropathy. The cerebrospinal fluid (CSF) contained both Epstein-Barr virus (EBV) DNA and antibody to EBV. This is the first report of an acute autonomic neuropathy with documented EBV infection in CSF.
Bennett
J L
JL
Department of Neurology, University of Colorado Health Sciences Center, Denver 80262, USA.
Mahalingam
R
R
Wellish
M C
MC
Gilden
D H
DH
D000328:Adult; D000914:Antibodies, Viral / Q000134:cerebrospinal fluid; D001342:Autonomic Nervous System Diseases / Q000134:cerebrospinal fluid / Q000821:virology*; D001483:Base Sequence; D004279:DNA, Viral / Q000134:cerebrospinal fluid; D006566:Herpesviridae Infections / Q000134:cerebrospinal fluid / Q000821:virology; D004854:Herpesvirus 4, Human / Q000235:genetics* / Q000276:immunology*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D015345:Oligonucleotide Probes / Q000235:genetics; D016133:Polymerase Chain Reaction; D014412:Tumor Virus Infections / Q000134:cerebrospinal fluid / Q000821:virology
D000914:Antibodies, Viral; D004279:DNA, Viral; D015345:Oligonucleotide Probes