Endocervical tubal metaplasia and adenocarcinoma in situ: role of immunohistochemistry for carcinoembryonic antigen and vimentin in differential diagnosis.
Eighteen cases of endocervical tubal metaplasia (tubal metaplasia) and 16 cases of adenocarcinoma in situ were reacted immunohistochemically for carcinoembryonic antigen (CEA) and vimentin. Whereas CEA was more frequently positive in adenocarcinoma in situ cases (63%) than in tubal metaplasia cases (39%), vimentin was not expressed in adenocarcinoma but was positive in 78% of cases of tubal metaplasia.
Marques
T
T
Department of Pathology, Faculdade de Ciências Médicas, Universidade Estadual de Campinas/Unicamp, Brazil.
Andrade
L A
LA
Vassallo
J
J
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D002278:Carcinoma in Situ / Q000175:diagnosis* / Q000473:pathology; D002584:Cervix Uteri / Q000276:immunology / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008679:Metaplasia / Q000175:diagnosis* / Q000473:pathology; D012189:Retrospective Studies; D014746:Vimentin / Q000032:analysis*
D002272:Carcinoembryonic Antigen; D014746:Vimentin