Severe renal vasoconstriction and anuria after intravenous urography in a patient with renal impairment.
Acute renal failure caused by radiocontrast agents remains a severe problem, particularly in patients with risk factors. There is debate concerning the pathophysiology of contrast media-induced acute renal failure, including, but not limited to, renal ischemia or tubular damage. Vascular ischemia is considered a major contributor because consistent changes in renal hemodynamics have been recorded experimentally. We describe a patient who has a typical course of contrast-associated renal failure manifested by severe renal vasoconstriction and backflow of the contrast agent during renal angiography performed after 6 days of an intravenous urography. Such degree of renal vasoconstriction is noteworthy in that this particular case might serve as a model in delineation of the pathogenetic mechanisms of acute renal failure after contrast media administration.
Arici
M
M
Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Erdem
Y
Y
Altun
B
B
Balkanci
F
F
Yasavul
U
U
Turgan
C
C
Cağlar
S
S
D058186:Acute Kidney Injury / Q000139:chemically induced; D000368:Aged; D001002:Anuria / Q000139:chemically induced*; D003287:Contrast Media / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D012077:Renal Artery / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000503:physiopathology; D014567:Urography; D014661:Vasoconstriction / Q000187:drug effects*
D003287:Contrast Media