[Kinetic study of the cyclization of the addition compound of ethyl mercaptoacetate on benzylideneacetophenone].
The study of the kinetic of cyclisation reaction of the additional compound of the mercaptoacetic ethylester on a benzylideneacetophenone was proposed. With the chromatography a retro-Michael reaction was obtained. The H NMR alone permitted to show the order 1 for the kinetic of cyclization and according to the amine used like reaction catalyst, two diastereoisomers could be formed.
Guinchard
C
C
Equipe de Chimie Thérapeutique, UFR des Sciences, Médicales et Pharmaceutiques, Besançon.
Dankar
A
A
Mercier
M F
MF
Xicluna
A
A
Robert
J F
JF
D002599:Chalcone / Q000008:administration & dosage / Q000493:pharmacokinetics*; D002851:Chromatography, High Pressure Liquid; D003500:Cyclization; D004338:Drug Combinations; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013237:Stereoisomerism; D013864:Thioglycolates / Q000008:administration & dosage / Q000493:pharmacokinetics*
D004338:Drug Combinations; D013864:Thioglycolates; D002599:Chalcone; C017487:2-mercaptoacetate