title: [Vogt-Koyanagi-Harada disease with cerebellar lesions demonstrated on MRI: a case report].
abstract: We reported unique magnetic resonance imaging (MRI) findings of a 57-year-old Japanese man who was diagnosed as Vogt-Koyanagi-Harada disease. This patient presented with complaints of a transient severe headache followed by a bilateral loss of visual acuity and truncal ataxia. Magnetic resonance imaging revealed abnormal contrast enhancement of both the uveas and the cerebellar vermis corresponding to his neurological abnormalities. The distribution and the nature of the resolution of this unusual pattern of contrast enhancement suggested that these MRI findings might illustrate transient destruction of the blood brain barrier or vascular extravasations. Such events might be representative of pathophysiology involving the central nervous system that occurred in patients with Vogt-Koyanagi-Harada disease.
authors.affiliation: Department of Medicine and Geriatrics, Kochi Medical School.
authors.forename: Y
authors.initials: Y
authors.lastname: Osaki
authors.forename: K
authors.initials: K
authors.lastname: Matsubayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Doi
authors.forename: T
authors.initials: T
authors.lastname: Ozawa
mesh_terms: D002524:Cerebellar Ataxia / Q000175:diagnosis / Q000209:etiology*; D002531:Cerebellum / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014607:Uveomeningoencephalitic Syndrome / Q000150:complications*