title: Parathyroid carcinoma with metastatic calcification identified by technetium-99m methylene diphosphonate scintigraphy.
abstract: We describe herein a case of parathyroid carcinoma accompanied with metastatic calcification identified by technetium-99m methylene diphosphonate (Tc-99m MDP) scintigraphy in the lungs, kidneys and stomach. Parathyroid carcinoma remains a rare disorder despite the increased prevalence of primary hyperparathyroidism. Metastatic calcification is noted infrequently even in primary hyperparathyroidism and it may cause respiratory failure. Tc-99m MDP scintigraphy three months after surgery showed a complete disappearance of Tc-99m uptake in the stomach and an obvious reduction in the kidneys but no significant change in the lungs, indicating metastatic calcification can be reversibly reabsorbed. This case indicates that the adequate excision of parathyroid carcinoma as well as the early detection of metastatic calcification by Tc-99m MDP are obligatory.
authors.affiliation: Department of Medicine, Dokkyo Koshigaya Hospital, Dokkyo University School of Medicine.
authors.forename: Y
authors.initials: Y
authors.lastname: Aso
authors.forename: A
authors.initials: A
authors.lastname: Sato
authors.forename: K
authors.initials: K
authors.lastname: Tayama
authors.forename: K
authors.initials: K
authors.lastname: Takanashi
authors.forename: H
authors.initials: H
authors.lastname: Satoh
authors.forename: Y
authors.initials: Y
authors.lastname: Takemura
mesh_terms: D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000209:etiology; D002277:Carcinoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000209:etiology; D008171:Lung Diseases / Q000000981:diagnostic imaging* / Q000209:etiology; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010282:Parathyroid Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D011877:Radionuclide Imaging; D012131:Respiratory Insufficiency / Q000209:etiology / Q000517:prevention & control; D013272:Stomach Diseases / Q000000981:diagnostic imaging* / Q000209:etiology; D013669:Technetium Tc 99m Medronate
chemical_list: D013669:Technetium Tc 99m Medronate