title: Local staging of prostate carcinoma with endorectal coil MRI: correlation with whole-mount radical prostatectomy specimens.
abstract: The purpose of this study was to investigate the accuracy of endorectal coil MRI in the local staging of prostate carcinoma. A total of 73 patients with biopsy-proven prostate carcinoma were examined at 0.5 T prior being submitted to radical prostatectomy. The gold standard was provided in all patients by findings at whole-mount sectioning of the surgical specimens. At pathology 28 patients had stage T2, 30 had stage T3a/b, and 15 had stage T3c lesions. Overall accuracy of endorectal coil MRI in defining local tumor stage was 82% (60 of 73 patients). Of 73 patients, 5 (7%) were underestimated and 8 (11%) overestimated. The sensitivity and the specificity of endorectal coil MRI in diagnosing capsular penetration were 95% and 82%, respectively. Seminal vesicle invasion was detected with 80% sensitivity and 93% specificity. Our data indicate that endorectal coil MRI is an accurate method for local staging of prostate cancer.
authors.affiliation: Department of Radiology, University of Pisa, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Bartolozzi
authors.forename: I
authors.initials: I
authors.lastname: Menchi
authors.forename: R
authors.initials: R
authors.lastname: Lencioni
authors.forename: S
authors.initials: S
authors.lastname: Serni
authors.forename: A
authors.initials: A
authors.lastname: Lapini
authors.forename: G
authors.initials: G
authors.lastname: Barbanti
authors.forename: A
authors.initials: A
authors.lastname: Bozza
authors.forename: A
authors.initials: A
authors.lastname: Amorosi
authors.forename: A
authors.initials: A
authors.lastname: Manganelli
authors.forename: M
authors.initials: M
authors.lastname: Carini
mesh_terms: D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods; D008297:Male; D009367:Neoplasm Staging; D011467:Prostate / Q000473:pathology; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000473:pathology*; D012680:Sensitivity and Specificity