An electrode to record the mouse cornea electroretinogram.
The mouse has become a popular model for the study of retinal degeneration, but an electrode suitable for recording electroretinograms from the mouse cornea is not available commercially. I developed a simple electrode suitable for the relatively small mouse eye by attaching a thin stainless-steel wire through the barrel of a 1-cc syringe. The end of the wire is formed into a coil by wrapping it around a 0.5- or 1.0-mm pin. The syringe barrel serves as a convenient way to hold the electrode in a goose-neck holder. This electrode has been used successfully to obtain electroretinograms from hundreds of mice as young as 14 days.
Goto
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Hines Veterans Affairs Hospital, IL, USA.
D000818:Animals; D003315:Cornea; D003623:Dark Adaptation; D004566:Electrodes; D004596:Electroretinography / Q000295:instrumentation*; D004867:Equipment Design; D051379:Mice; D008822:Mice, Transgenic; D010775:Photic Stimulation; D012160:Retina / Q000502:physiology*