Suitability of polyvinylidene fluoride (PVDF) piping in pharmaceutical ultrapure water applications.
This paper discusses polyvinylidene fluoride (PVDF) as an alternative to stainless steel in pharmaceutical ultrapure water piping systems. Two leading Swiss companies, a piping systems supplier and a pharmaceutical manufacturer, teamed together to jointly carryout the research. Issues addressed are metallic contamination, microbial concerns, piping system functionally and ozone resistance. Comparisons between PVDF and stainless steel are made when necessary.
Burkhart
M
M
Georg Fischer Piping Systems, Schaffhausen, Switzerland.
Wermelinger
J
J
Setz
W
W
Müller
D
D
D004339:Drug Compounding; D004345:Drug Industry / Q000592:standards; D008567:Membranes, Artificial; D011145:Polyvinyls / Q000737:chemistry*; D013193:Stainless Steel; D018508:Water Purification / Q000379:methods*; D005465:Fluorocarbon Polymers
D008567:Membranes, Artificial; D011145:Polyvinyls; D013193:Stainless Steel; C024865:polyvinylidene fluoride; D005465:Fluorocarbon Polymers