title: [Goodpasture's syndrome with negative renal immunofluorescence].
abstract: The diagnosis of Goodpasture's syndrome is established by the clinical setting of diffuse alveolar hemorrhage and glomerulonephritis, and the demonstration of circulating or tissue-bound antibasement membrane antibodies. However, cases of Goodpasture's syndrome limited either to the lungs or kidneys have been reported. The absence of immune deposits from renal biopsy specimens of a patient with Goodpasture's syndrome, even with normal renal function, is exceptional. We report here a case of Goodpasture's syndrome characterized by direct immunofluorescence staining of the transbronchial biopsy specimen, and with direct negative immunofluorescence on renal biopsy specimen.
authors.affiliation: Secciones de Neumología, Nefrología, Hospital General de Albacete.
authors.forename: M
authors.initials: M
authors.lastname: Izquierdo Patrón
authors.forename: M
authors.initials: M
authors.lastname: Haro Estarriol
authors.forename: R
authors.initials: R
authors.lastname: Coloma Navarro
authors.forename: E
authors.initials: E
authors.lastname: Andrés
authors.forename: L
authors.initials: L
authors.lastname: Iñíguez
mesh_terms: D000328:Adult; D019867:Anti-Glomerular Basement Membrane Disease / Q000175:diagnosis*; D005189:False Positive Reactions; D019085:Fluorescent Antibody Technique, Direct; D006801:Humans; D008297:Male