Murine infection with lymphocytic choriomeningitis virus following gastric inoculation.
Laboratory studies of arenaviruses have been limited to parenteral routes of infection; however, recent epidemiological studies implicate virus ingestion as a natural route of infection. Accordingly, we developed a model for oral and gastric infection with lymphocytic choriomeningitis virus to enable studies of mucosal transmission and vaccination by this additional route.
Rai
S K
SK
Department of Pathology and Laboratory Medicine, University of Wisconsin Medical School, Madison 53713, USA.
Cheung
D S
DS
Wu
M S
MS
Warner
T F
TF
Salvato
M S
MS
D000818:Animals; D004195:Disease Models, Animal; D007082:Ileum / Q000648:ultrastructure / Q000821:virology; D008216:Lymphocytic Choriomeningitis; D008217:Lymphocytic choriomeningitis virus; D051379:Mice; D008854:Microscopy, Electron; D013270:Stomach / Q000821:virology*