Antimicrobial isoflavanones from Desmodium canum.
Bioassay-directed fractionation of Desmodium canum resulted in the isolation and characterization of three antimicrobial isoflavonones. These compounds, namely, desmodianones A, B and C, were assigned the structures 5,7,2'-trihydroxy-6,6"-dimethyl-6"-(4-methylpent-3- enyl)pyrano(2",3";4',5')isoflavanone, 5,2',4'-trihydroxy-7-methoxy-6-methyl-8-(3-methylbut-2-enyl)-is oflavanone, and 5,7,2',4'-tetrahydroxy-6-methyl-5'-(3,7-dimethylocta-2,6-dienyl )-isoflavanone, respectively.
Monache
G D
GD
Centro Chimica Recettori del C.N.R., Università Cattolica, Roma, Italy.
Botta
B
B
Vinciguerra
V
V
de Mello
J F
JF
de Andrade Chiappeta
A
A
D000890:Anti-Infective Agents / Q000302:isolation & purification* / Q000494:pharmacology*; D005591:Chemical Fractionation; D007529:Isoflavones / Q000302:isolation & purification* / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000302:isolation & purification* / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
D000890:Anti-Infective Agents; D007529:Isoflavones; D010936:Plant Extracts; C099081:desmodianone A; C099082:desmodianone B; C099083:desmodianone C