title: [Breast-preserving (conservative) therapy of breast cancer].
abstract: Conservative surgery (sectoral or segmental + axillary dissection) was performed in 278 patients with breast cancer (T1-2N0M0) at the Institute Clinic in 1990-1995. Following thorough morphological examination. 148 patients (53.2%) were selected to form a clinical study group for an investigation of the role of postoperative radiotherapy in the conservative treatment of breast cancer. Two groups-irradiation of the remaining breast tissue and controls-were formed on the basis of randomized data. Follow-up continued 3-60 months (average duration-37.7 months). Local recurrence was detected in 3 out of 73 (4.2%) patients of group I. A similar relapse was detected in 6 out of 75 (8.0%) patients of group II. No significant difference in total survival rates in the two groups was observed (97.3 and 96.0%; p > 0.05).
authors.forename: V F
authors.initials: VF
authors.lastname: Semiglazov
authors.forename: S V
authors.initials: SV
authors.lastname: Kanaev
authors.forename: O L
authors.initials: OL
authors.lastname: Chagunava
authors.forename: O A
authors.initials: OA
authors.lastname: Ivanova
authors.forename: K M
authors.initials: KM
authors.lastname: Pozharisskiĭ
authors.forename: O F
authors.initials: OF
authors.lastname: Chepik
authors.forename: A G
authors.initials: AG
authors.lastname: Vesnin
authors.forename: A N
authors.initials: AN
authors.lastname: Zaĭtsev
authors.forename: A A
authors.initials: AA
authors.lastname: Orlov
authors.forename: N N
authors.initials: NN
authors.lastname: Krinitsina
authors.forename: N I
authors.initials: NI
authors.lastname: Barash
authors.forename: I K
authors.initials: IK
authors.lastname: Seleznev
authors.forename: N S
authors.initials: NS
authors.lastname: Migmanova
authors.forename: R T
authors.initials: RT
authors.lastname: Popova
authors.forename: V G
authors.initials: VG
authors.lastname: Ivanov
authors.forename: O M
authors.initials: OM
authors.lastname: Golubeva
authors.forename: A A
authors.initials: AA
authors.lastname: Bozhok
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D005260:Female; D006801:Humans; D015412:Mastectomy, Segmental; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant; D016019:Survival Analysis; D016896:Treatment Outcome