Efficacy of combination antiretroviral therapy.
Combination therapy with two nucleosides has been shown to improve clinical outcome compared with zidovudine monotherapy. There is every expectation that more potent antiretroviral combination regimens will increase the clinical benefits. However, this remains to be proven definitely. The increasing number of choices of antiretroviral therapies create new challenges for those studying and those using these therapies.
Collier
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Clinical Trials Unit, University of Washington, Seattle, USA.
D000998:Antiviral Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D017320:HIV Protease Inhibitors / Q000627:therapeutic use; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D009705:Nucleosides / Q000627:therapeutic use; D012192:Retroviridae Infections / Q000188:drug therapy*; D018894:Reverse Transcriptase Inhibitors / Q000627:therapeutic use
D000998:Antiviral Agents; D017320:HIV Protease Inhibitors; D009705:Nucleosides; D018894:Reverse Transcriptase Inhibitors; D007372:Interferons