The paradoxical role of lipid peroxidation on carcinogenesis and tumor growth: a commentary.
Lipid peroxidation has been shown to both enhance carcinogenesis and to have an anticarcinogenic effect. This paradox is of great relevance to the fields of free radical biology, biochemistry, pathology, nutrition and oncology among others and needs to be addressed. A proper understanding of this issue can be a key to more effective treatment of malignant tumors in the near future.
González
M J
MJ
University of Puerto Rico, School of Public Health, San Juan, Puerto Rico.
Riordan
N H
NH
D016588:Anticarcinogenic Agents; D000975:Antioxidants; D016923:Cell Death; D002471:Cell Transformation, Neoplastic; D005609:Free Radicals / Q000378:metabolism; D006801:Humans; D015227:Lipid Peroxidation; D008954:Models, Biological; D009369:Neoplasms / Q000235:genetics / Q000473:pathology / Q000503:physiopathology* / Q000517:prevention & control
D016588:Anticarcinogenic Agents; D000975:Antioxidants; D005609:Free Radicals