Factor V Q 506 mutation in children with thrombosis.
The factor V Leiden mutation in 12-children with thrombosis and in 20 controls was investigated. Five heterozygous individuals and 1 homozygous individual among the cases with thrombosis and 1 heterozygous individual among controls were found. Central nervous system thromboses were increased in children with the factor V mutation, associated with protein S deficiency.
Gurgey
A
A
Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Mesci
L
L
Renda
Y
Y
Olcay
L
L
Kocak
N
N
Erdem
G
G
D016022:Case-Control Studies; D002648:Child; D005165:Factor V / Q000235:genetics*; D005260:Female; D006579:Heterozygote; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009154:Mutation; D018455:Protein S Deficiency / Q000235:genetics; D013927:Thrombosis / Q000235:genetics*
D005165:Factor V