title: Extending the quasi-steady state approximation by changing variables.
abstract: The parameter domain for which the quasi-steady state assumption is valid can be considerably extended merely by a simple change of variable. This is demonstrated for a variety of biologically significant examples taken from enzyme kinetics, immunology and ecology.
authors.affiliation: Theoretical Biology, Utrecht University, The Netherlands, jbo@alive.biol.ruu.nl
authors.forename: J A
authors.initials: JA
authors.lastname: Borghans
authors.forename: R J
authors.initials: RJ
authors.lastname: de Boer
authors.forename: L A
authors.initials: LA
authors.lastname: Segel
mesh_terms: D000818:Animals; D001671:Biochemistry / Q000379:methods; D004463:Ecology; D004798:Enzymes / Q000378:metabolism*; D007158:Immunologic Techniques; D007700:Kinetics; D008433:Mathematics; D008962:Models, Theoretical; D011235:Predatory Behavior
chemical_list: D004798:Enzymes