title: Anaphylactic shock during hysteroscopy using Hyskon solution: case report and review of adverse reactions and their treatment.
abstract: Dextran 70 (Hyskon) solution, as many other substances, is in current use as distension medium during hysteroscopy. The advantages of Hyskon solution are its nonconductivity and immiscibility with blood, allowing good visibility during operative hysteroscopy. Adverse reactions to Hyskon are mainly attributable to the drug's antigenic properties and include severe anaphylactic reactions and fatalities. We report a case of anaphylactic shock during hysteroscopy using Hyskon solution as the distension medium, review the adverse reactions of Hyskon and summarize the treatment modalities used to decrease the incidence of the rare but serious adverse reactions with its use.
authors.affiliation: Department of Obstetrics and Gynecology, Israel Institute of Technology, Haifa.
authors.forename: Y
authors.initials: Y
authors.lastname: Perlitz
authors.forename: M
authors.initials: M
authors.lastname: Oettinger
authors.forename: K
authors.initials: K
authors.lastname: Karam
authors.forename: B
authors.initials: B
authors.lastname: Lipshitz
authors.forename: K
authors.initials: K
authors.lastname: Simon
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000707:Anaphylaxis / Q000139:chemically induced* / Q000503:physiopathology / Q000628:therapy; D003911:Dextrans / Q000009:adverse effects*; D004298:Dopamine / Q000627:therapeutic use; D004809:Ephedrine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015907:Hysteroscopy / Q000009:adverse effects*; D012121:Respiration, Artificial; D012996:Solutions
chemical_list: D000305:Adrenal Cortex Hormones; D003911:Dextrans; D012996:Solutions; D004809:Ephedrine; D004298:Dopamine