title: Is deep vein thrombosis surveillance warranted in high-risk trauma patients?
abstract: BACKGROUND
  Deep vein thrombosis (DVT) has been reported to occur in 20% to 40% of high-risk trauma patients if no prophylaxis is used. The purpose of this study was to determine the incidence of DVT and utility of a screening program in a high-risk group of trauma patients for whom routine DVT prophylaxis was utilized.
  
  
  METHODS
  Of 3,154 trauma admissions over a 20-month period, 343 patients (10.9%) identified as high risk based on established criteria (prolonged bed rest, Glasgow coma score (GCS) of 7, spinal injury, lower extremity or pelvic fracture) were placed on a prospective surveillance protocol using color-flow duplex scanning and received thromboembolic prophylaxis.
  
  
  RESULTS
  Twenty-three thromboembolic complications occurred, including 20 DVTs (5.8%) and 3 pulmonary emboli ([PE] 1%). Univariate analysis showed that the risk of DVT was related to age (52.6 + 19.9 years versus 38.1 + 18.5; P = 0.001), a longer hospital stay (31.4 versus 17.8 days; P = 0.001), or the presence of spinal fracture (12.6% versus 3.5%; P = 0.01). Discriminant function analysis revealed that length of stay, intensive care unit days, age, and GCS allowed correct classification of those who did not develop DVT in 97% of cases but was only correct in 15% of cases in predicting those who would develop DVT. Injury severity score (ISS) was not predictive in this multivariate analysis. Seventeen (85%) DVTs were unsuspected clinically. Study patients received an average of 3.5 studies at an overall charge of $313,330 to detect 17 clinically unsuspected DVTs (5%). This represents about 5% of the total bed charges for these patients, or $18,000 per DVT.
  
  
  CONCLUSIONS
  These results suggest that standard use of DVT prophylaxis in a high-risk trauma population leads to a low incidence of DVT and that a screening protocol is effective in detecting unsuspected DVTs. Use of a surveillance protocol, however, may reduce but will not eliminate the incidence of pulmonary emboli in this patient population.
authors.affiliation: Department of Surgery, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.
authors.forename: J J
authors.initials: JJ
authors.lastname: Piotrowski
authors.forename: J J
authors.initials: JJ
authors.lastname: Alexander
authors.forename: C P
authors.initials: CP
authors.lastname: Brandt
authors.forename: C R
authors.initials: CR
authors.lastname: McHenry
authors.forename: J P
authors.initials: JP
authors.lastname: Yuhas
authors.forename: D
authors.initials: D
authors.lastname: Jacobs
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D017722:Hospital Charges; D006801:Humans; D015601:Injury Severity Score; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011159:Population Surveillance; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011655:Pulmonary Embolism / Q000517:prevention & control; D012306:Risk; D012307:Risk Factors; D013923:Thromboembolism / Q000517:prevention & control; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000191:economics / Q000209:etiology / Q000517:prevention & control*; D013997:Time Factors; D018615:Ultrasonography, Doppler, Color; D014947:Wounds and Injuries / Q000150:complications* / Q000000981:diagnostic imaging / Q000191:economics