title: Prospective evaluation of antibiotic prophylaxis prior to cystometrogram and/or cystogram studies: oral versus intramuscular routes.
abstract: OBJECTIVE
  To compare empiric single-dose gentamicin versus culture-specific oral antibiotics as prophylaxis before cystometrogram and/or cystogram. Comparisons with regards to infection, patient preference, and cost were made.
  
  
  METHODS
  Prospective randomized control trial.
  
  
  METHODS
  Inpatient and outpatient rehabilitation hospital.
  
  
  METHODS
  Seventy received oral antibiotics and 72 received intramuscular gentamicin.
  
  
  METHODS
  Cystometrograms and/or cystograms were performed.
  
  
  METHODS
  Patient interviewed and chart reviewed for infection. Convenience and comfort were rated by patient.
  
  
  RESULTS
  Oral antibiotics and gentamicin have similar efficacy. Patients rated the gentamicin more convenient (p < .001) and comfortable (p < .01) than oral antibiotics. Gentamicin is less expensive.
  
  
  CONCLUSIONS
  Gentamicin should be used as the method of choice for cystometrogram/cystogram prophylaxis.
authors.affiliation: Magee Rehabilitation Hospital, Philadelphia, PA 19102-1177, USA.
authors.forename: G W
authors.initials: GW
authors.lastname: Fried
authors.forename: G
authors.initials: G
authors.lastname: Goetz
authors.forename: S
authors.initials: S
authors.lastname: Potts-Nulty
authors.forename: G
authors.initials: G
authors.lastname: Solomon
authors.forename: H M
authors.initials: HM
authors.lastname: Cioschi
authors.forename: W E
authors.initials: WE
authors.lastname: Staas
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019072:Antibiotic Prophylaxis / Q000009:adverse effects / Q000191:economics; D001424:Bacterial Infections / Q000209:etiology / Q000517:prevention & control*; D016009:Chi-Square Distribution; D003258:Consumer Behavior; D003362:Cost-Benefit Analysis; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage* / Q000009:adverse effects / Q000191:economics; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014567:Urography / Q000009:adverse effects / Q000379:methods*
chemical_list: D005839:Gentamicins