Type 1 and type 2: a fundamental dichotomy for all T-cell subsets.
Cytokine secretion is not confined to CD4+ T cells; rather, Type 1 and Type 2 populations of CD8+ and gamma delta T cells can also be generated in vitro and isolated from in vivo situations. These subsets and their physiological functions are significant.
Carter
L L
LL
Trudeau Institute, Saranac Lake, NY 12983, USA. carter@northnet.org
Dutton
R W
RW
D000818:Animals; D006801:Humans; D018417:Th1 Cells / Q000276:immunology* / Q000502:physiology*; D018418:Th2 Cells / Q000276:immunology* / Q000502:physiology*