title: Benzene-induced bone marrow cell depression caused by inhibition of the conversion of pre-interleukins-1alpha and -1beta to active cytokines by hydroquinone, a biological reactive metabolite of benzene.
authors.affiliation: Department of Biochemistry and Molecular Biology, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
authors.forename: R
authors.initials: R
authors.lastname: Niculescu
authors.forename: J F
authors.initials: JF
authors.lastname: Renz
authors.forename: G F
authors.initials: GF
authors.lastname: Kalf
mesh_terms: D000818:Animals; D001554:Benzene / Q000633:toxicity*; D001711:Biotransformation; D001853:Bone Marrow / Q000187:drug effects; D001854:Bone Marrow Cells; D002273:Carcinogens / Q000633:toxicity*; D016207:Cytokines / Q000096:biosynthesis*; D006801:Humans; D006873:Hydroquinones / Q000378:metabolism* / Q000494:pharmacology; D007375:Interleukin-1 / Q000378:metabolism*; D009153:Mutagens / Q000378:metabolism* / Q000494:pharmacology
chemical_list: D002273:Carcinogens; D016207:Cytokines; D006873:Hydroquinones; D007375:Interleukin-1; D009153:Mutagens; D001554:Benzene; C031927:hydroquinone