title: Migraine and sickle-cell disorders: is there a cause for concern?
abstract: Migraine and sickle-cell disease are common diseases, and may coexist in the same individual. Such a chance association is potentially dangerous because the two disorders may act synergistically to cause major neurological complications which may be permanent and contribute to the well-known mortality of sickle-cell disease. In theory, it is possible to minimize the risk of adverse sequelae of this combination of common maladies.
authors.affiliation: Department of Paediatric Neurology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: M S
authors.initials: MS
authors.lastname: Salman
mesh_terms: D000700:Analgesics / Q000009:adverse effects / Q000627:therapeutic use; D000755:Anemia, Sickle Cell / Q000150:complications* / Q000401:mortality / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000097:blood / Q000209:etiology / Q000503:physiopathology; D002648:Child; D006261:Headache / Q000503:physiopathology; D006801:Humans; D015994:Incidence; D002532:Intracranial Aneurysm / Q000453:epidemiology; D008881:Migraine Disorders / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D010507:Periodicity; D012307:Risk Factors; D014839:Vomiting
chemical_list: D000700:Analgesics