Recurring episodes of meningitis (Mollaret's meningitis) with one showing an association with herpes simplex virus type 2.
Benign recurrent aseptic (Mollaret's) meningitis is a rare disease of unknown aetiology. We report the case of a 27-year-old woman who experienced three episodes of lymphocytic meningitis. Human Simplex Virus (HSV) type 2 DNA was detected in the CSF by PCR amplification indicating the diagnosis of recurrent HSV type 2 meningitis. Our observation suggests that search of herpes virus DNA by PCR amplification on CSF may be useful in unexplained recurrent meningitis.
Bachmeyer
C
C
Department of Internal Medicine, Cochin Hospital, Paris, France.
de la Blanchardière
A
A
Lepercq
J
J
Dhôte
R
R
Grateau
G
G
Detilleux
M
M
Tournaire
M
M
Christoforov
B
B
D000328:Adult; D002555:Cerebrospinal Fluid / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D018258:Herpesvirus 2, Human; D006801:Humans; D008587:Meningitis, Viral / Q000821:virology*; D016133:Polymerase Chain Reaction
D004279:DNA, Viral