title: Cervical carcinoma: do fast SE and fat suppression techniques improve MR tumor staging at 0.5 T?
abstract: OBJECTIVE
  Our goal was to compare fast SE (FSE) with T2-weighted conventional SE (CSE) MRI of cervical carcinoma and to evaluate the potential advantage of fat suppression technique.
  
  
  METHODS
  We compared the tissue contrasts between cervical carcinoma and the surrounding tissues in 24 patients. The following MR sequences were obtained at 0.5 T: T1-weighted CSE (450/20 ms), T2-weighted CSE (2,500/45, 90), and T2-weighted FSE (4,800/120), the latter with and without fat suppression using fat-selective prepulses.
  
  
  RESULTS
  T2-weighted FSE MRI provided significantly better contrasts between tumor and normal cervical stroma (p < 0.001) and between tumor and rectum wall (p < 0.05) than T2-weighted CSE MRI. T1-weighted SE MRI gave the highest tissue contrast between tumor and parametrial tissue (p < 0.001). Fat suppression did not further improve tissue contrasts.
  
  
  CONCLUSIONS
  MR staging of cervical carcinoma is best done with the combination of T1-weighted SE and T2-weighted FSE images, without additional fat suppression.
authors.affiliation: Department of Radiology, Leiden University Hospital, The Netherlands.
authors.forename: S
authors.initials: S
authors.lastname: Postema
authors.forename: L A
authors.initials: LA
authors.lastname: Peters
authors.forename: J
authors.initials: J
authors.lastname: Hermans
authors.forename: J B
authors.initials: JB
authors.lastname: Trimbos
authors.forename: P M
authors.initials: PM
authors.lastname: Pattynama
mesh_terms: D002584:Cervix Uteri / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009367:Neoplasm Staging; D012007:Rectum / Q000473:pathology; D001743:Urinary Bladder / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014599:Uterus / Q000473:pathology