Establishment of cell lines stably expressing mumps virus glycoproteins.
We established two cell lines that stably express hemagglutinin-neuraminidase (HeLa-HN) and fusion proteins (HeLa-F) of a fusogenic strain of mumps virus. Infection of HeLa-F cells with a nonfusogenic strain resulted in induction of extensive cell fusion. On the other hand, HeLa-HN cells appeared resistant to cell fusion induced by mumps virus infection.
Hishiyama
M
M
Department of Viral Disease and Vaccine Control, National Institute of Health, Tokyo.
Tanabayashi
K
K
Takeuchi
K
K
Yamada
A
A
D000818:Animals; D002460:Cell Line; D002522:Chlorocebus aethiops; D005434:Flow Cytometry; D006168:Guinea Pigs; D015707:HN Protein / Q000096:biosynthesis; D006367:HeLa Cells; D006801:Humans; D009109:Mumps virus / Q000378:metabolism*; D014162:Transfection; D014709:Vero Cells; D014760:Viral Fusion Proteins / Q000096:biosynthesis*
D015707:HN Protein; D014760:Viral Fusion Proteins