[Treatment of tuberculosis].
The standard antituberculous treatment consists during the first 2 months of daily rifampin 10 mg/kg, isoniazid 4-5 mg/kg and pyrazinamide 25 mg/kg, with ethambutol 20 mg/kg in case of suspicion of drug resistance. The second phase of treatment consists of 4 months rifampin and isoniazid at the same daily dosage. Two or three drugs combination pills simplify the treatment. An early treatment and a good follow up are prognostic factors of individual success and tuberculosis epidemic reduction. In case of multidrug resistance, susceptibility tests should be obtained before new initiation of treatment.
Dautzenberg
B
B
Service de pneumologie Groupe hospitalier Pitié-Salpbtnère, Paris.
D000293:Adolescent; D000328:Adult; D000995:Antitubercular Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008826:Microbial Sensitivity Tests; D011247:Pregnancy; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000517:prevention & control
D000995:Antitubercular Agents