Vancomycin-resistant Aureobacterium species cellulitis and bacteremia in a patient with acute myelogenous leukemia.
A 39-year-old male with acute myelogenous leukemia and concomitant porphyria cutanea tarda was admitted to the hospital for consolidation chemotherapy of his leukemia. During his hospitalization, he developed cellulitis of the left hand and persistent bacteremia with a yellow-pigmented, nonfermenting coryneform bacterium that was identified as Aureobacterium sp. The portal of entry for the Aureobacterium infection was probably through the skin lesions due to porphyria cutanea tarda. The infection developed while the patient was receiving vancomycin prophylaxis, and the vancomycin MIC for the isolate was 32 micrograms/ml.
Nolte
F S
FS
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, USA. fnolte@emory.edu
Arnold
K E
KE
Sweat
H
H
Winton
E F
EF
Funke
G
G
D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016470:Bacteremia / Q000150:complications / Q000382:microbiology*; D015373:Bacterial Typing Techniques; D002481:Cellulitis / Q000150:complications / Q000382:microbiology; D004352:Drug Resistance, Microbial; D006093:Gram-Positive Asporogenous Rods / Q000187:drug effects*; D016908:Gram-Positive Bacterial Infections / Q000150:complications / Q000382:microbiology* / Q000401:mortality; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications*; D008297:Male; D008826:Microbial Sensitivity Tests; D014640:Vancomycin / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D014640:Vancomycin