title: Biosynthetic capacities of actinomycetes. 5. Dioxolides, novel secondary metabolites from Streptomyces tendae.
abstract: Dioxolides, a novel class of secondary metabolites were detected by a HPLC-diode array screening technique in the culture filtrate of Streptomyces tendae Tu 4042. The compounds show no biological activity against Gram-positive and Gram-negative bacteria, yeasts and fungi. Besides dioxolides, which consist of an unusual substituted dioxolane ring, anhydroshikimate and para-hydrobenzamide were detected by this technique. Both compounds were not yet described as natural products.
authors.affiliation: Biologisches Institut, Universitaet Tuebingen, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Blum
authors.forename: I
authors.initials: I
authors.lastname: Groth
authors.forename: J
authors.initials: J
authors.lastname: Rohr
authors.forename: H P
authors.initials: HP
authors.lastname: Fielder
mesh_terms: D013302:Streptomyces / Q000378:metabolism*