Danger - pathogen on the premises! Immunological tolerance.
Recent results show that immune responses can be induced in neonatal mice. Do they really refute the traditional view that the ability to discriminate between 'self' and 'non-self' is a fundamental property of the immune system?
Janeway
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CA
Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
Goodnow
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CC
Medzhitov
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R
D000222:Adaptation, Physiological; D000818:Animals; D000831:Animals, Newborn / Q000276:immunology; D007107:Immune System / Q000502:physiology*; D007239:Infections / Q000276:immunology; D051379:Mice; D018448:Models, Immunological