Esophageal and duodenal atresia in a fetus with Down's syndrome: prenatal sonographic features.
Ultrasound examination of a 22-week fetus demonstrated a grossly distended stomach and proximal duodenum, with a large cystic area in the chest. There was associated polyhydramnios. A presumptive diagnosis of duodenal atresia with a congenital diaphragmatic hernia was made. Analysis of a fetal blood sample showed that the fetus had Down's syndrome. Histological examination after termination of the pregnancy revealed the unusual combination of duodenal and esophageal atresia, with an intact diaphragm.
Chitty
L S
LS
Paediatric Research Unit, Guy's Hospital, London, UK.
Goodman
J
J
Seller
M J
MJ
Maxwell
D
D
D000328:Adult; D004314:Down Syndrome / Q000150:complications* / Q000000981:diagnostic imaging; D004380:Duodenal Obstruction / Q000150:complications / Q000151:congenital* / Q000000981:diagnostic imaging; D004933:Esophageal Atresia / Q000150:complications / Q000000981:diagnostic imaging*; D005260:Female; D005865:Gestational Age; D006548:Hernia, Diaphragmatic / Q000150:complications / Q000000981:diagnostic imaging; D006801:Humans; D007409:Intestinal Atresia / Q000150:complications / Q000000981:diagnostic imaging*; D007621:Karyotyping; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D016216:Ultrasonography, Prenatal