A contiguous high-resolution radiation hybrid map of 44 loci from the distal portion of the long arm of human chromosome 5.
A contiguous high-resolution map of 44 loci from a 35-Mb portion of the distal region of the long arm of human chromosome 5, q21-q35, was produced using radiation hybrid (RH) mapping in conjunction with a natural deletion mapping panel. The map includes 30 genes, four sequence-tagged site (STS) loci, and 10 DNA markers. Newly mapped markers fill two gap regions that were present in previous maps, between markers FER-IL4 and IL3-IL9. Identifying the position of genes on the physical map aids in positional cloning efforts and contributes to our understanding of the overall organization of the human genome.
Warrington
J A
JA
Department of Biological Chemistry, College of Medicine, University of California, Irvine 92717, USA. janet_warrington@affymetrix.com
Wasmuth
J J
JJ
D000818:Animals; D016466:CHO Cells; D002874:Chromosome Mapping / Q000379:methods*; D002895:Chromosomes, Human, Pair 5 / Q000235:genetics*; D006224:Cricetinae; D005796:Genes / Q000235:genetics; D005819:Genetic Markers / Q000235:genetics; D006801:Humans; D006822:Hybrid Cells; D008969:Molecular Sequence Data; D011827:Radiation; D016324:Sequence Tagged Sites
D005819:Genetic Markers