title: The role of molecular techniques in the understanding of emerging infections.
abstract: Emerging infections are defined as infections that are newly identified or recognized, or those whose incidence in humans has significantly increased over the past 20 years. The interaction of several factors contributes to the emergence of infectious disease, including changes in human behavior, technological advances, economic development, increased international travel, microbial adaptation and lapses in public health measures. Biomedical research has allowed us to identify and classify previously uncultured pathogens, characterize microbial virulence factors, create new diagnostic tests and develop vaccines. Here, we highlight a few emerging infections and illustrate the role that molecular medicine has played in furthering our understanding of these diseases.
authors.affiliation: Merck Research Labs BL3-3, Blue Bell, PA 19422, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Sable
authors.forename: G L
authors.initials: GL
authors.lastname: Mandell
mesh_terms: D001474:Bartonella Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D018804:Hantavirus Pulmonary Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy / Q000821:virology; D019142:Hemorrhagic Fever, Ebola / Q000453:epidemiology / Q000821:virology; D006801:Humans; D008967:Molecular Biology; D016133:Polymerase Chain Reaction; D012514:Sarcoma, Kaposi / Q000453:epidemiology / Q000821:virology; D013290:Streptococcal Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D013297:Streptococcus pyogenes