Extension of the Rorschach--Hazlewood theoretical model for spin-lattice relaxation in biological systems to low frequencies.
The water-biopolymer cross-relaxation model, proposed by H. E. Rorschach and C. F. Hazlewood (RH) [J. Magn. Reson. 70, 79 (1986)], explains the Larmor frequency dependence of T1 in many biological systems. However, the RH theory fails at low Larmor frequencies. In this paper, a more general version of the RH theory has been developed. This theory is valid at all frequencies. Use of the new expression for the spin-lattice relaxation rate (1/T1), earlier published experimental data in H2O/D2O bovine serum albumin, which had been measured over a wide frequency range (10 kHz to 100 MHz), were fitted over the entire frequency range. The agreement between theory and the experimental data is excellent. Theoretical expressions for the rotating-frame spin-lattice relaxation rate (1/T1(rho)) were also obtained.
Hackmann
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Department of Physics, University of Utah, Salt Lake City 84112, USA.
Ailion
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Ganesan
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Laicher
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Goodrich
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Cutillo
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D000465:Algorithms; D000818:Animals; D002417:Cattle; D003903:Deuterium; D004578:Electron Spin Resonance Spectroscopy; D009682:Magnetic Resonance Spectroscopy; D008962:Models, Theoretical; D015203:Reproducibility of Results; D012709:Serum Albumin; D014867:Water
D012709:Serum Albumin; D014867:Water; D003903:Deuterium