title: Outcome at 4 to 5 years of age in children recovered from neonatal chronic lung disease.
abstract: Outcomes were compared for 31 very-low-birthweight children recovered from chronic lung disease and 31 very-low-birthweight controls. All children had been free of major abnormalities on neonatal cranial ultrasonography. At 4 to 5 years of age, children were examined by a pediatrician and tested by a psychologist who administered the Wechsler Preschool and Primary Scale of Intelligence-Revised. Despite similar medical outcomes, the children who had had neonatal chronic lung disease had lower Full-scale IQs (median 83 vs 87) and Performance IQs (79 vs 90). Median Verbal IQ was similar in the two groups (85 vs 87). A higher proportion of children who had had chronic lung disease had Full-scale IQ < 70 (8/31 [26%] vs 1/31 [3%]) and Performance IQ < 70 (8/31 [26%] vs 0/31). These effects persisted after adjustment for confounding factors.
authors.affiliation: Department of Pediatrics, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC 27157, USA.
authors.forename: T M
authors.initials: TM
authors.lastname: O'Shea
authors.forename: D J
authors.initials: DJ
authors.lastname: Goldstein
authors.forename: R A
authors.initials: RA
authors.lastname: deRegnier
authors.forename: C I
authors.initials: CI
authors.lastname: Sheaffer
authors.forename: D D
authors.initials: DD
authors.lastname: Roberts
authors.forename: R G
authors.initials: RG
authors.lastname: Dillard
mesh_terms: D002675:Child, Preschool; D002908:Chronic Disease; D003072:Cognition Disorders / Q000175:diagnosis; D003289:Convalescence; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases; D008171:Lung Diseases; D008297:Male