Neurological frontal signs and neuropsychological deficits in schizophrenic patients.
A higher prevalence of neurological signs (NS) has been described in schizophrenic patients when compared with controls or patients with other mental illnesses. This study, which includes a sample of 66 DSM-IIIR schizophrenics, was designed to assess the relationship between 7 frontal neurologic signs described by Luria and cognitive disturbances measured by an exhaustive neuropsychological battery. There was a statistically significant relationships between the frontal signs and the cognitive deficits (mean shared variance was 22%) which persisted after correcting for the influence of age, education, and duration of illness.
Cuesta
M J
MJ
Psychiatric Unit I, Virgen del Camino Hospital, Pamplona, Spain.
Peralta
V
V
de Leon
J
J
D000293:Adolescent; D000328:Adult; D003072:Cognition Disorders / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D005260:Female; D005625:Frontal Lobe / Q000503:physiopathology*; D006801:Humans; D008182:Luria-Nebraska Neuropsychological Battery; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000175:diagnosis* / Q000503:physiopathology; D012565:Schizophrenic Psychology