title: Necrobiosis lipoidica treated with topical tretinoin.
abstract: Necrobiosis lipoidica is often resistant to therapeutic intervention. Lesions are atrophic and frequently ulcerate. A case is presented in which atrophy was diminished by the application of topical tretinoin. The practical and theoretical use of topical tretinoin in this disorder is reviewed.
authors.affiliation: Division of Dermatology, Cooper Hospital/University Medical Center, UMDNJ-Robert Wood Johnson Medical School at Camden, USA.
authors.forename: W R
authors.initials: WR
authors.lastname: Heymann
mesh_terms: D000287:Administration, Topical; D048909:Diabetes Complications; D005260:Female; D006801:Humans; D007641:Keratolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D007866:Leg; D008875:Middle Aged; D009335:Necrobiosis Lipoidica / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D014212:Tretinoin / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D007641:Keratolytic Agents; D014212:Tretinoin