Prospective evaluation of antibiotic prophylaxis prior to cystometrogram and/or cystogram studies: oral versus intramuscular routes.
OBJECTIVE
To compare empiric single-dose gentamicin versus culture-specific oral antibiotics as prophylaxis before cystometrogram and/or cystogram. Comparisons with regards to infection, patient preference, and cost were made.


METHODS
Prospective randomized control trial.


METHODS
Inpatient and outpatient rehabilitation hospital.


METHODS
Seventy received oral antibiotics and 72 received intramuscular gentamicin.


METHODS
Cystometrograms and/or cystograms were performed.


METHODS
Patient interviewed and chart reviewed for infection. Convenience and comfort were rated by patient.


RESULTS
Oral antibiotics and gentamicin have similar efficacy. Patients rated the gentamicin more convenient (p < .001) and comfortable (p < .01) than oral antibiotics. Gentamicin is less expensive.


CONCLUSIONS
Gentamicin should be used as the method of choice for cystometrogram/cystogram prophylaxis.
Fried
G W
GW
Magee Rehabilitation Hospital, Philadelphia, PA 19102-1177, USA.
Goetz
G
G
Potts-Nulty
S
S
Solomon
G
G
Cioschi
H M
HM
Staas
W E
WE
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019072:Antibiotic Prophylaxis / Q000009:adverse effects / Q000191:economics; D001424:Bacterial Infections / Q000209:etiology / Q000517:prevention & control*; D016009:Chi-Square Distribution; D003258:Consumer Behavior; D003362:Cost-Benefit Analysis; D005260:Female; D005839:Gentamicins / Q000008:administration & dosage* / Q000009:adverse effects / Q000191:economics; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014567:Urography / Q000009:adverse effects / Q000379:methods*
D005839:Gentamicins