A case of Churg-Strauss syndrome: tissue diagnosis established by sigmoidoscopic rectal biopsy.
A case is presented of Churg-Strauss syndrome in a young man in whom the definitive diagnostic procedure was a full thickness sigmoidoscopic rectal biopsy, with submucosal sampling. Gastrointestinal changes in Churg-Strauss syndrome, a rare systemic illness characterised by asthma, blood and tissue eosinophilia, vasculitis, and granulomatous inflammation are common but poorly reported. The endoscopic and histopathological features of a case are described and emphasise the potential value of a limited sigmoidoscopy in establishing the diagnosis, when lower gastrointestinal symptoms are present.
Leen
E J
EJ
Department of Histopathology, Guy's Hospital, London.
Rees
P J
PJ
Sanderson
J D
JD
Wilkinson
M L
ML
Filipe
M I
MI
D000328:Adult; D001706:Biopsy; D015267:Churg-Strauss Syndrome / Q000473:pathology*; D006801:Humans; D008297:Male; D012002:Rectal Diseases / Q000473:pathology*; D012810:Sigmoid Diseases / Q000473:pathology; D012812:Sigmoidoscopy / Q000379:methods