title: Botulinum toxin treatment of Hertwig-Magendie sign.
abstract: Hypertropia, not due to the usual causes and associated with a central nervous system disorder, should be suspected as being a skew deviation (Hertwig-Magendie sign). We describe a new case of this supranuclear disorder, presumably related to cocaine-induced stroke. This disorder was treated by botulinum A toxin (Oculinum) injection into the superior rectus muscle. Follow-up one year later found the vertical deviation resolved.
authors.affiliation: Department of Ophthalmology, Ramón y Cajal Hospital, Madrid, Spain.
authors.forename: G
authors.initials: G
authors.lastname: Rebolleda
authors.forename: F J
authors.initials: FJ
authors.lastname: Muñoz Negrete
mesh_terms: D000328:Adult; D019274:Botulinum Toxins, Type A / Q000627:therapeutic use*; D002561:Cerebrovascular Disorders / Q000139:chemically induced / Q000150:complications; D003042:Cocaine / Q000009:adverse effects; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009294:Narcotics / Q000009:adverse effects; D009465:Neuromuscular Agents / Q000627:therapeutic use*; D013285:Strabismus / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D014792:Visual Acuity
chemical_list: D009294:Narcotics; D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A; D003042:Cocaine