title: Transient hemolytic anemia after transjugular intrahepatic portosystemic stent shunt.
abstract: Management of variceal bleeding secondary to portal hypertension constitutes a challenging issue, particularly in child's C cirrhotic patients. Recently, transjugular placement of self-expanding metallic stents in the liver (TIPS), creating a shunt between the portal and hepatic branches has provided a safe and promising therapeutic approach in this clinical situation. We report here the case of a 66-year-old male cirrhotic patient who developed a moderately severe clinical picture of Coombsnegative hemolytic anemia (serum hemoglobin, 93 g/l, serum bilirubin 160.74 umol/L (9.4 mg/dl), indirect 6.3 mg/dl (107.73 umol/L); serum LDH 1220 mu/l, reticulocytes, 5.1%, serum ferritin 1221 micrograms/l, schistocytes in peripheral blood smear) the week after undergoing a TIPS, suggesting the development of microangiopathic hemolytic anaemia secondary to red blood cell disruption by passing through the metallic network of the stent.
authors.affiliation: Dpto de Medicina Interna, Hospital Universitario de Canarias, La Laguna, Tenerife, Canary Islands, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Garcia-Rebollo
authors.forename: E
authors.initials: E
authors.lastname: González-Reimers
authors.forename: F
authors.initials: F
authors.lastname: Santolaria-Fernández
authors.forename: F
authors.initials: F
authors.lastname: Diaz-Romero
authors.forename: F
authors.initials: F
authors.lastname: Rodriguez-Moreno
authors.forename: A
authors.initials: A
authors.lastname: Martinez-Riera
mesh_terms: D000368:Aged; D000743:Anemia, Hemolytic / Q000209:etiology*; D006801:Humans; D008103:Liver Cirrhosis / Q000601:surgery; D008297:Male; D019168:Portasystemic Shunt, Transjugular Intrahepatic / Q000009:adverse effects*; D012086:Reoperation; D015607:Stents / Q000009:adverse effects