title: Severe renal vasoconstriction and anuria after intravenous urography in a patient with renal impairment.
abstract: Acute renal failure caused by radiocontrast agents remains a severe problem, particularly in patients with risk factors. There is debate concerning the pathophysiology of contrast media-induced acute renal failure, including, but not limited to, renal ischemia or tubular damage. Vascular ischemia is considered a major contributor because consistent changes in renal hemodynamics have been recorded experimentally. We describe a patient who has a typical course of contrast-associated renal failure manifested by severe renal vasoconstriction and backflow of the contrast agent during renal angiography performed after 6 days of an intravenous urography. Such degree of renal vasoconstriction is noteworthy in that this particular case might serve as a model in delineation of the pathogenetic mechanisms of acute renal failure after contrast media administration.
authors.affiliation: Department of Radiology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Arici
authors.forename: Y
authors.initials: Y
authors.lastname: Erdem
authors.forename: B
authors.initials: B
authors.lastname: Altun
authors.forename: F
authors.initials: F
authors.lastname: Balkanci
authors.forename: U
authors.initials: U
authors.lastname: Yasavul
authors.forename: C
authors.initials: C
authors.lastname: Turgan
authors.forename: S
authors.initials: S
authors.lastname: Cağlar
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced; D000368:Aged; D001002:Anuria / Q000139:chemically induced*; D003287:Contrast Media / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D012077:Renal Artery / Q000000981:diagnostic imaging / Q000187:drug effects* / Q000503:physiopathology; D014567:Urography; D014661:Vasoconstriction / Q000187:drug effects*
chemical_list: D003287:Contrast Media