Occupational allergic contact dermatitis and airborne contact dermatitis from 5 fungicides in a vineyard worker. Cross-reactions between fungicides of the dithiocarbamate group?
We report a patient with occupational contact dermatitis due to sensitization to mancozeb and perhaps metiram used in a vineyard. Patch testing showed strong allergic patch test reactions to 2 of the commercially available preparations used (Dithane Ultra and Polyram WG). Further patch tests showed allergic patch test reactions to mancozeb (0.5 and 1% pet.), a weak reaction to metiram (1% pet.) as well as to 4 other fungicides of the dithiocarbamate group (maneb, nabam, propineb and zineb), which had never been used in the vineyard.
Koch
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Hautklinik der Universität des Saarlandes, Homburg/Saar, Germany.
D000328:Adult; D000336:Aerosols; D000382:Agricultural Workers' Diseases / Q000175:diagnosis* / Q000209:etiology; D003429:Cross Reactions; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology; D009783:Dermatitis, Occupational / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D005659:Fungicides, Industrial / Q000009:adverse effects*; D006801:Humans; D008344:Maneb / Q000009:adverse effects; D010328:Patch Tests; D015038:Zineb / Q000009:adverse effects
D000336:Aerosols; D005659:Fungicides, Industrial; D008344:Maneb; C013099:mancozeb; D015038:Zineb