[Study of the effect of chicken embryo homogenate on the growth and metastasis of sarcoma of Pliss in rats].
The effects of injection of 6 day-old homogenate of chicken embryo tissue on sarcoma of Pliss have been investigated. It was found to drastically inhibit said malignancy in rats and to increase their survival. Histological study revealed extensive necrosis of tumor tissue as well as formation of fibro-vascular structures showing characteristic leukocyte-macrophageal infiltration in the treated animals unlike untreated controls and those injected with cyclophosphamide. A link between activation of cellular immunity and antitumor effects of embryonal tissue homogenate is suggested.
Rodionov
S I
SI
Tat'kov
S I
SI
Pak
N A
NA
D000818:Animals; D002642:Chick Embryo; D005260:Female; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012513:Sarcoma, Experimental / Q000517:prevention & control* / Q000556:secondary*