Immune response to mouse mammary tumour virus.
Superantigens of mouse mammary tumor virus induce a strong cognate interaction between T cells and B cells. In addition to amplifying the virus-infected B-cell pool, this superantigen-driven interaction leads to the differentiation of virus-specific B cells into plasma cells. Successful interaction between T cells and B cells is required for completion of the viral life cycle.
Luther
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Ludwig Institute of Cancer Research, Lausanne Branch, University of Lausanne, Chemin des Boveresses 155, CH-1066 Epalinges, Switzerland. sluther@eliot.unil.ch
Acha-Orbea
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D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D008211:Lymphocyte Cooperation / Q000276:immunology*; D008324:Mammary Tumor Virus, Mouse / Q000276:immunology*; D051379:Mice; D016747:Minor Lymphocyte Stimulatory Antigens / Q000276:immunology; D012192:Retroviridae Infections / Q000276:immunology; D018089:Superantigens / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D014412:Tumor Virus Infections / Q000276:immunology
D016747:Minor Lymphocyte Stimulatory Antigens; D018089:Superantigens