Neutrophil taurine in psoriasis.
Neutrophil taurine was measured in 30 subjects presenting with chronic stable plaque-type psoriasis. The taurine concentration expressed per 5 x 10(6) cells was significantly lower (p < 0.002) in these subjects compared to neutrophil taurine measured in 20 control subjects. In view of increasing evidence proposing possible roles for taurine in maintaining normal neutrophil function coupled with previously observed anti-inflammatory effects of taurine in vitro, an assessment of possible roles of taurine in the aetiology of psoriasis is discussed.
Stapleton
P P
PP
Department of Biochemistry, Trinity College, Dublin.
Molloy
A M
AM
Rogers
S
S
Bloomfield
F J
FJ
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009504:Neutrophils / Q000378:metabolism; D011565:Psoriasis / Q000209:etiology* / Q000503:physiopathology; D012016:Reference Values; D013654:Taurine / Q000032:analysis / Q000097:blood*
D013654:Taurine