title: Structural changes leading to increased enzymatic activity in an engineered variant of Bacillus lentus subtilisin.
authors.affiliation: Genencor International, South San Francisco, CA 94080, USA.
authors.forename: R
authors.initials: R
authors.lastname: Bott
authors.forename: J
authors.initials: J
authors.lastname: Dauberman
authors.forename: L
authors.initials: L
authors.lastname: Wilson
authors.forename: G
authors.initials: G
authors.lastname: Ganshaw
authors.forename: H
authors.initials: H
authors.lastname: Sagar
authors.forename: T
authors.initials: T
authors.lastname: Graycar
authors.forename: D
authors.initials: D
authors.lastname: Estell
mesh_terms: D001407:Bacillus / Q000201:enzymology* / Q000235:genetics; D003196:Computer Graphics; D014644:Genetic Variation; D006860:Hydrogen Bonding; D006868:Hydrolysis; D007700:Kinetics; D016297:Mutagenesis, Site-Directed; D015202:Protein Engineering; D012694:Serine / Q000737:chemistry*; D013329:Structure-Activity Relationship; D013381:Subtilisins / Q000737:chemistry* / Q000235:genetics / Q000502:physiology
chemical_list: D012694:Serine; D013381:Subtilisins