title: A Monte Carlo evaluation of the channel ratio scatter correction method.
abstract: Several methods exist to eliminate the contribution of scattered photons during imaging. One of these, the channel ratio (CR) scatter correction technique, uses the change in the ratio of counts from two symmetrical adjacent energy windows straddling the energy photopeak. The accuracy of the results depends upon the assumption that the ratio of the scatter components in the two windows (H value) is constant and is independent of the relative size of the scatter contribution. In this study a Monte Carlo simulation was used to investigate the behaviour of the scatter component for different source sizes at different depths. Four disc sources containing a 99Tcm solution were simulated at different depths as imaged with a scintillation camera. Two 10% energy windows with 5% offsets to either side of the 140 keV photopeak of 99Tcm were used. The ratio of the scattered counts in the lower energy window to the scattered counts in the upper window (true H value) was determined from the simulation for each source at every depth. Since it is impossible to measure the true H value at different organ depths during a clinical study, the use of an average H value was considered. Scatter correction was applied to the images simulated at the various depths in water. The geometric mean was calculated and attenuation correction performed assuming mono-exponential attenuation. For quantitation purposes the corrected counts were expressed in terms of a references source. The choice of the reference source yielding the best quantitative results was also investigated. Results of this Monte Carlo simulation study show that although the true H value depends on both source size and depth of the source in the scattering medium, the CR scatter correction technique can be applied successfully when an average H value is used.
authors.affiliation: Biophysics Department, University of the Orange Free State, Bloemfontein, South Africa.
authors.forename: H
authors.initials: H
authors.lastname: Naudé
authors.forename: A
authors.initials: A
authors.lastname: van Aswegen
authors.forename: C P
authors.initials: CP
authors.lastname: Herbst
authors.forename: M G
authors.initials: MG
authors.lastname: Lötter
authors.forename: P H
authors.initials: PH
authors.lastname: Pretorius
mesh_terms: D001699:Biometry; D055592:Biophysical Phenomena; D001703:Biophysics; D006801:Humans; D009010:Monte Carlo Method; D017785:Photons; D011877:Radionuclide Imaging / Q000706:statistics & numerical data*; D012542:Scattering, Radiation; D012984:Software; D013667:Technetium
chemical_list: D013667:Technetium