Transcriptional elongation and cancer. Tumorigenesis.
Recent discoveries indicate that transcriptional elongation is an important regulatory step in gene expression, and that deregulation of elongation can lead to the development of certain malignancies.
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Howard Hughes Medical Research Institute, Program in Molecular Medicine, University of Massachusetts Medical Center, 373 Plantation Street, Worcester, Massachusetts 01605, USA.
Green
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D015972:Gene Expression Regulation, Neoplastic; D016147:Genes, Tumor Suppressor; D006801:Humans; D009369:Neoplasms / Q000235:genetics*; D014158:Transcription, Genetic