title: Genetic epidemiology of the Mitsuda reaction in leprosy.
abstract: This study comprised 544 nuclear families with 2,925 individuals tested for the Mitsuda reaction, from the Campinas region in Brazil. Segregation analyses suggest the segregation of a major gene (chi 2(1) = 0.07 - 0.07 = 0, p = 1), by failing to reject the hypothesis of Mendelian transmission and by rejecting the hypothesis of nontransmission of a major gene (chi 2(3) = 0.07 - 0.0 = 0.07, p > 0.99; chi 2(2) = 198.28 - 0.0 = 198.28, p < 0.0001).
authors.affiliation: Departamento de Genética-Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
authors.forename: M
authors.initials: M
authors.lastname: Feitosa
authors.forename: H
authors.initials: H
authors.lastname: Krieger
authors.forename: I
authors.initials: I
authors.lastname: Borecki
authors.forename: B
authors.initials: B
authors.lastname: Beiguelman
authors.forename: D C
authors.initials: DC
authors.lastname: Rao
mesh_terms: D030342:Genetic Diseases, Inborn / Q000235:genetics*; D006801:Humans; D007918:Leprosy / Q000235:genetics*; D008957:Models, Genetic; D010641:Phenotype