title: The relationship between in vitro and in vivo venous compliance measurement.
abstract: OBJECTIVE
  To assess the relationship between in vitro and in vivo venous compliance measurement.
  
  
  METHODS
  Prospective, blind study.
  
  
  METHODS
  Patients affected by primary varicose veins and classified in accord with the new CEAP criteria (C2-6/S, Ep, AS1-4/p17-18, PR) underwent blind venous compliance measurements using two different methods. 1) In vivo assessment of the compliance of the greater saphenous vein by duplex scanning, for diameter, and a needle transducer, for venous pressure measurements. 2) In vitro standard compliance assessment of the same vein segment after its excision.
  
  
  RESULTS
  The compliance values obtained with the two methods showed a significant degree of correlation, which improved with increasing intravenous pressures.
  
  
  CONCLUSIONS
  In vivo compliance assessment of the saphenous vein was validated by the relationship with the standard in vitro measurement.
authors.affiliation: Department of Surgery and Vascular Laboratory, University of Ferrara, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Zamboni
authors.forename: M G
authors.initials: MG
authors.lastname: Marcellino
authors.forename: F
authors.initials: F
authors.lastname: Portaluppi
authors.forename: R
authors.initials: R
authors.lastname: Manfredini
authors.forename: C V
authors.initials: CV
authors.lastname: Feo
authors.forename: D
authors.initials: D
authors.lastname: Quaglio
authors.forename: A
authors.initials: A
authors.lastname: Liboni
mesh_terms: D004548:Elasticity; D006801:Humans; D012501:Saphenous Vein / Q000503:physiopathology*; D014648:Varicose Veins / Q000175:diagnosis* / Q000503:physiopathology; D014654:Vascular Patency / Q000502:physiology; D014655:Vascular Resistance / Q000502:physiology; D014690:Venous Pressure / Q000502:physiology