Liver disease in extrahepatic malignancy.
The various causes of liver disease in malignancy have been reviewed. Metastatic lesions, hepatotoxicity from oncotherapeutic agents, infections, and vascular complications must all be considered. A systematic approach beginning with a detailed history and physical examination usually provides clinicians with early clues as to the etiology of the liver disease in malignancy. The advent of new laboratory tests and the technologic advances in abdominal imaging have provided powerful new tools for the diagnosis and management of patients with liver disease. Understanding how these tests could be properly used will enhance the likelihood that important liver disease will not be missed in patients with malignancies.
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Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, USA.
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D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D008113:Liver Neoplasms / Q000175:diagnosis / Q000503:physiopathology / Q000556:secondary*; D009369:Neoplasms / Q000150:complications*