title: Structural characterization of human Ad4bp (SF-1) gene.
abstract: Ad4BP (or steroidogenic factor 1, SF-1) has been implicated to be an essential transcriptional factor for steroidogenesis as well as for the development of the reproductive axis. We elucidated the structure of the human Ad4BP gene. The gene is about 30 kb long and is split into 7 exons including a non-coding exon 1. The deduced amino acid sequence of the human Ad4BP consists of 461 amino acid residues and was highly homologous to those of other mammalian species.
authors.affiliation: Third Department of Internal Medicine, Graduate School of Medical Science, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Oba
authors.forename: T
authors.initials: T
authors.lastname: Yanase
authors.forename: M
authors.initials: M
authors.lastname: Nomura
authors.forename: K
authors.initials: K
authors.lastname: Morohashi
authors.forename: R
authors.initials: R
authors.lastname: Takayanagi
authors.forename: H
authors.initials: H
authors.lastname: Nawata
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D004247:DNA; D004268:DNA-Binding Proteins / Q000235:genetics*; D051717:Fushi Tarazu Transcription Factors; D018398:Homeodomain Proteins; D006801:Humans; D008969:Molecular Sequence Data; D018160:Receptors, Cytoplasmic and Nuclear; D013045:Species Specificity; D054339:Steroidogenic Factor 1; D014157:Transcription Factors / Q000235:genetics*; D014158:Transcription, Genetic
chemical_list: D004268:DNA-Binding Proteins; D051717:Fushi Tarazu Transcription Factors; D018398:Homeodomain Proteins; C515057:NR5A1 protein, human; D018160:Receptors, Cytoplasmic and Nuclear; D054339:Steroidogenic Factor 1; D014157:Transcription Factors; D004247:DNA