title: Normal developmental changes in carotid arterial blood flow measured by Doppler flowmetry in children.
abstract: We examined the developmental changes in carotid arterial blood flow in a group of neonates, infants, and children using a Doppler flowmeter. The mean, maximum and minimum carotid arterial blood flow (CABF) were measured serially in 35 healthy newborns during the first 5 days of life (total 175 records), and in 62 healthy children aged 1 month to 13 years. In newborns, the mean CABF increased significantly on the second day of life, while the maximum and minimum CABFs increased significantly every day during the first 3 days of life. The mean, maximum, and minimum CABFs increased steadily and significantly in those older than 1 month but reached a plateau after 2 to 4 years of age. Our results indicate that CABF changes with age in early life, reflecting a change in cardiac contraction and carotid-cerebral circulatory system. The measurement of CABF by Doppler flowmetry may be useful for examining cardiac and carotid-cerebral circulatory disorder.
authors.affiliation: Department of Pediatrics, Oita Medical University, School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kojo
authors.forename: T
authors.initials: T
authors.lastname: Ogawa
authors.forename: K
authors.initials: K
authors.lastname: Yamada
mesh_terms: D000293:Adolescent; D000375:Aging / Q000502:physiology*; D001783:Blood Flow Velocity; D002339:Carotid Arteries / Q000000981:diagnostic imaging*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D012016:Reference Values; D012212:Rheology; D018608:Ultrasonography, Doppler