Prenatal diagnosis of a chest wall hamartoma and sternal cleft.
We present the prenatal evaluation and diagnosis of a disorganized chest wall hamartoma with underlying sternal cleft in a family with a prior offspring with the VATER association. The possibility that these conditions are linked to mesodermal defects with a common pathogenic etiology is suggested.
Rose
N C
NC
Division of Reproductive Genetics, University of Pennsylvania Medical Center, Philadelphia 19104, USA.
Coleman
B G
BG
Wallace
D
D
Gaupman
K
K
Ruchelli
E
E
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D006222:Hamartoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D013249:Sternum / Q000002:abnormalities* / Q000000981:diagnostic imaging; D013896:Thoracic Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology; D013909:Thorax / Q000000981:diagnostic imaging*; D016216:Ultrasonography, Prenatal