title: Surgical treatment of isolated secundum atrial septal defect in patients more than 50 years old.
abstract: BACKGROUND
  Arrhythmia-related thromboembolic accidents continue to occur in patients even after closure of secundum atrial septal defect. Older age is usually not a contraindication to the repair of an atrial septal defect. To assess the importance of the type of management in elderly patients with atrial septal defect our clinical experience is reviewed.
  
  
  METHODS
  Between 1974 and 1994, 49 patients 50 years of age or older (average, 57.4 years) underwent surgical closure of secundum atrial septal defect. All patients have been followed up for 2 to 21 years (mean, 9.7 years).
  
  
  RESULTS
  There were no operative deaths. Functional classes in most of the patients were improved after operation. There were two cerebrovascular thromboembolic accidents with one permanent neurologic dysfunction, hemiparesis, and one septal dehiscence in the early postoperative period. One patient (2%) died of renal failure 6 years after operation, late arrhythmias developed in 3 patients (6%), 3 patients had a late stroke (6%), and 1 patient was not available for follow-up.
  
  
  CONCLUSIONS
  Long-term operative results are satisfactory and beneficial to the quality of life in elderly patients. Because there is no safe and effective nonsurgical alternative to surgical closure, atrial septal defect repair in elderly patients without severe pulmonary vascular disease should not be delayed once the diagnosis had been made.
authors.affiliation: Department of Cardiovascular Surgery, Akita University School of Medicine, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Shibata
authors.forename: T
authors.initials: T
authors.lastname: Abe
authors.forename: R
authors.initials: R
authors.lastname: Kuribayashi
authors.forename: S
authors.initials: S
authors.lastname: Sekine
authors.forename: K
authors.initials: K
authors.lastname: Seki
authors.forename: I
authors.initials: I
authors.lastname: Yamagishi
authors.forename: J
authors.initials: J
authors.lastname: Chanda
mesh_terms: D000367:Age Factors; D000368:Aged; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006344:Heart Septal Defects, Atrial / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications