title: Canine osteosarcoma: amputation and chemotherapy.
abstract: One of the most important advances in veterinary oncology during the past 10 years has been the use of adjuvant chemotherapy for treatment of the micrometastases of canine osteosarcoma. This article reviews the biologic behavior of osteosarcoma and discusses chemotherapy with the two agents known to be effective: cisplatin and doxorubicin.
authors.affiliation: Department of Surgery, Tufts University School of Veterinary Medicine, North Grafton, MA 01536, USA.
authors.forename: J
authors.initials: J
authors.lastname: Berg
mesh_terms: D000671:Amputation, Surgical / Q000592:standards / Q000662:veterinary*; D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000592:standards / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000592:standards / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000662:veterinary*; D002945:Cisplatin / Q000592:standards / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004283:Dog Diseases / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D004285:Dogs; D004317:Doxorubicin / Q000592:standards / Q000627:therapeutic use*; D009362:Neoplasm Metastasis / Q000473:pathology; D012516:Osteosarcoma / Q000188:drug therapy / Q000601:surgery / Q000662:veterinary*
chemical_list: D000903:Antibiotics, Antineoplastic; D000970:Antineoplastic Agents; D004317:Doxorubicin; D002945:Cisplatin