title: Cytochrome P450-dependent oxidation of fatty acids.
abstract: Cytochrome P450-dependent monooxygenases from plants catalyse in-chain and omega hydroxylation as well as epoxidation of medium- and long-chain fatty acids. Recent research efforts have clarified that there are multiple forms of cytochrome P450 involved in these reactions, each of which possesses distinguishable substrate specificity. The biological roles of these distinct P450 forms are poorly understood. However, evidence suggests that some may play an important role in the biosynthesis of plant cuticles. We review current knowledge on the induction and inhibition of activities as well as the regio- and stereo-specificity of the distinct forms so far characterised.
authors.affiliation: Département d'Enzymologie Cellulaire et Moléculaire, Institut de Biologie Moléculaire des Plantes, CNRS-UPR 406, Strasbourg, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Salaün
authors.forename: C
authors.initials: C
authors.lastname: Helvig
mesh_terms: D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism*; D005227:Fatty Acids / Q000378:metabolism*; D010084:Oxidation-Reduction; D010944:Plants / Q000201:enzymology*
chemical_list: D005227:Fatty Acids; D003577:Cytochrome P-450 Enzyme System