Failure to support a pseudoautosomal locus for schizophrenia.
Evidence for a pseudoautosomal locus for schizophrenia was sought through an assessment of the psychiatric status of the uncles and aunts (n = 30) of schizophrenic patients. The proportion of affected paternal uncles did not differ from that of affected paternal aunts. Likewise, the proportion of affected maternal aunts did not differ from that of affected maternal uncles. The research design used in this study failed to support the pseudoautosomal hypothesis of schizophrenia.
Ponnudurai
R
R
Department of Psychiatry, Madras Medical College, India.
D000328:Adult; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D002874:Chromosome Mapping; D005260:Female; D006580:Genetic Carrier Screening; D005820:Genetic Testing; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000175:diagnosis / Q000235:genetics*; D012729:Sex Chromosome Aberrations / Q000235:genetics*