Electromyographic changes of corpus cavernosum due to papaverine and nitroprusside in veno-occlusive dysfunction.
OBJECTIVE
We compared electrical activity of the corpus cavernosum after intracavernous papaverine and nitroprusside injections. Some aspects of the androgen modulator system in patients with veno-occlusive dysfunction are discussed.


METHODS
Electromyography of the corpus cavernosum was performed before and 1 day after intracavernous injection of 60 mg. papaverine and 400 micrograms. sodium nitroprusside in 22 patients with veno-occlusive dysfunction. Changes in duration and amplitude of electromyographic potentials were compared in groups with and without incoordination patterns.


RESULTS
The decreases in electrical amplitude and duration in 15 patients with a negative incoordination pattern, and increases in 7 with a positive pattern were more significant with intracavernous sodium nitroprusside than with papaverine injections.


CONCLUSIONS
Electromyographic changes were more prominent with nitroprusside than with papaverine, which demonstrates the use of nitroprusside when performing corpus cavernosum electromyography.
Kayigil
O
O
Urologic Clinics of TCDD Ankara Hospital, Turkey.
Atahan
O
O
Metin
A
A
D004576:Electromyography / Q000187:drug effects; D006801:Humans; D018783:Impotence, Vasculogenic / Q000503:physiopathology*; D008297:Male; D009130:Muscle, Smooth / Q000187:drug effects* / Q000503:physiopathology*; D009599:Nitroprusside / Q000494:pharmacology*; D010208:Papaverine / Q000494:pharmacology*; D010413:Penis / Q000187:drug effects* / Q000503:physiopathology*; D013997:Time Factors; D014665:Vasodilator Agents / Q000494:pharmacology*
D014665:Vasodilator Agents; D009599:Nitroprusside; D010208:Papaverine