title: Population study of the STRs HUMTH01 (including a new variant) and HUMVWA31A in Catalonia (northeast Spain).
abstract: Allele and genotype frequencies for 2 short tandem repeat loci were determined in a population sample from Catalonia (Spain) using the polymerase chain reaction. After denaturing PAG electrophoresis, seven common and one variant (13.3) alleles were identified for HUMTH01 in a sample of 234 unrelated individuals, and seven alleles were found for HUMVWA31A in 162 individuals. No deviation from Hardy-Weinberg equilibrium was found. The observed heterozygosities are 76.92 and 79.62 respectively. The discrimination power determined for the individual loci is 0.928 and 0.937 respectively.
authors.affiliation: Department of Legal Medicine, Faculty of Medicine, University of Barcelona, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Gené
authors.forename: E
authors.initials: E
authors.lastname: Huguet
authors.forename: P
authors.initials: P
authors.lastname: Moreno
authors.forename: C
authors.initials: C
authors.lastname: Sánchez
authors.forename: A
authors.initials: A
authors.lastname: Carracedo
authors.forename: J
authors.initials: J
authors.lastname: Corbella
mesh_terms: D000483:Alleles; D000941:Antigens / Q000235:genetics*; D002874:Chromosome Mapping; D004247:DNA / Q000235:genetics*; D005787:Gene Frequency / Q000235:genetics; D006580:Genetic Carrier Screening; D014644:Genetic Variation / Q000235:genetics*; D005828:Genetics, Population; D006801:Humans; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics*; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics*; D013030:Spain; D014841:von Willebrand Factor / Q000276:immunology
chemical_list: D000941:Antigens; C029417:Von Willebrand antigen; D014841:von Willebrand Factor; D004247:DNA