Screening of nonfatty fish for organochlorine pesticide residues by solid-phase extraction cleanup: interlaboratory study.
Six U.S. Food and Drug Administration laboratories participated in an Interlaboratory trial of a solid-phase extraction cleanup method for determination of pesticides in nonfatty seafood products. The participants analyzed control and fortified (about 0.050 ppm lindane, heptachlor epoxide, p,p'-DDE, and endrin) croaker and flounder samples and a sea trout sample containing incurred p,p'-DDE residues. Mean recoveries of the fortified residues from the fish ranged from 89.1 to 107.8%. The within-laboratory coefficients of variation (CVs) ranged from 4.2 to 8.5%, and the among-laboratory CVs ranged from 10.9 to 26.5%. The 6 laboratories reported a mean value of 0.040 ppm p,p'-DDE in a fish sample which contained incurred residues. The same value (0.040 ppm) was obtained by using official methodology. The within-laboratory CVs ranged from 3.5 to 18.3%, and the among-laboratory CV was 17.3%.
Schenck
F J
FJ
U.S. Food and Drug Administration, Baltimore District Laboratory, MD 21201, USA.
D000704:Analysis of Variance; D000818:Animals; D002849:Chromatography, Gas; D003633:Dichlorodiphenyl Dichloroethylene / Q000032:analysis / Q000378:metabolism; D004732:Endrin / Q000032:analysis / Q000378:metabolism; D005399:Fishes / Q000378:metabolism*; D005504:Food Analysis; D005506:Food Contamination / Q000032:analysis*; D006534:Heptachlor Epoxide / Q000032:analysis / Q000378:metabolism; D001556:Hexachlorocyclohexane / Q000032:analysis / Q000378:metabolism; D007306:Insecticides / Q000032:analysis* / Q000378:metabolism; D010573:Pesticide Residues / Q000032:analysis*; D015203:Reproducibility of Results; D013237:Stereoisomerism; D014481:United States; D014486:United States Food and Drug Administration
D007306:Insecticides; D010573:Pesticide Residues; D006534:Heptachlor Epoxide; D003633:Dichlorodiphenyl Dichloroethylene; D001556:Hexachlorocyclohexane; D004732:Endrin