Successful treatment of chylothorax by bleomycin for Gorham's disease.
A patient with idiopathic osteolysis in the thoracolumbar spine who developed severe chylothorax after a spinal operation is described. Irradiation and pleural adhesion therapies with minocycline and bleomycin were undertaken to control the chylothorax. Pleural adhesion therapy with bleomycin proved effective in treating this patient. Magnetic resonance imaging was performed to detect the lesion. T1 weighted imaging was particularly useful in diagnosing the lesion and evaluating the degree of fusion in the spine.
Aoki
M
M
Department of Orthopedic Surgery, Nagoya University School of Medicine, Japan.
Kato
F
F
Saito
H
H
Mimatsu
K
K
Iwata
H
H
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001761:Bleomycin / Q000627:therapeutic use*; D002916:Chylothorax / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010015:Osteolysis, Essential / Q000150:complications / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications; D011859:Radiography; D013131:Spine / Q000473:pathology
D000900:Anti-Bacterial Agents; D001761:Bleomycin