title: Neonatal intestinal perforation caused by intestinal muscularis defect associated with vascular ectasia.
abstract: We describe a rare case of a viable preterm infant who developed a spontaneous localized perforation of the small bowel caused by a segmental absence of the intestinal musculature and associated with vascular ectasia. The findings may support a causal relationship between absence of the intestinal muscle coat and a vascular network disorder which may be responsible for the gastroenteric defect.
authors.affiliation: Division of Neonatology, Medical College of Pennsylvania, Philadelphia 19129, USA.
authors.forename: D
authors.initials: D
authors.lastname: Wurtzel
authors.forename: R F
authors.initials: RF
authors.lastname: Nicosia
authors.forename: A
authors.initials: A
authors.lastname: Yoskovitch
authors.forename: A B
authors.initials: AB
authors.lastname: Zubrow
mesh_terms: D000199:Actins / Q000032:analysis; D000293:Adolescent; D003106:Colon / Q000737:chemistry / Q000473:pathology; D004108:Dilatation, Pathologic / Q000150:complications / Q000473:pathology; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007077:Ileal Diseases / Q000209:etiology* / Q000473:pathology; D007082:Ileum / Q000737:chemistry / Q000473:pathology; D007150:Immunohistochemistry; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000209:etiology* / Q000473:pathology; D007416:Intestinal Perforation / Q000209:etiology* / Q000473:pathology; D008297:Male; D009130:Muscle, Smooth / Q000737:chemistry / Q000473:pathology*; D011247:Pregnancy; D014652:Vascular Diseases / Q000150:complications* / Q000473:pathology; D014841:von Willebrand Factor / Q000032:analysis
chemical_list: D000199:Actins; D014841:von Willebrand Factor