Vascular disease of the lower extremities in diabetes mellitus.
Vascular disease, neuropathy, and infection act synergistically to cause diabetic foot ulceration. Appropriate care is hindered by misconceptions about microvascular disease. Recent advances and success with extreme distal revascularization combined with surgical management of infection have greatly improved salvage of the diabetic foot. Success is enhanced by a multidisciplinary team approach.
LoGerfo
F W
FW
Department of Surgery, Harvard Medical School, Boston, Massachusetts, USA.
Gibbons
G W
GW
D048909:Diabetes Complications; D003925:Diabetic Angiopathies / Q000209:etiology* / Q000503:physiopathology; D017719:Diabetic Foot / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D007511:Ischemia / Q000150:complications / Q000209:etiology* / Q000503:physiopathology; D007866:Leg / Q000098:blood supply* / Q000601:surgery; D014652:Vascular Diseases / Q000209:etiology* / Q000503:physiopathology