title: Flexible fibre-optic bronchoscopy in the management of lung complications in cystic fibrosis.
abstract: Flexible fibre-optic bronchoscopy was performed under sedation in 24 children with cystic fibrosis. In eight cases bronchoscopy was carried out as a therapeutic procedure. Most children were subjectively improved, but objective evidence of change was minimal. Useful information was obtained in 9/16 children who underwent the procedure for diagnostic purposes. Information included sensitive identification of organisms responsible for lower respiratory symptoms in non-expectorating cases and identification of unsuspected gastro-oesophageal reflux.
authors.affiliation: Department of Paediatrics, Southampton University Hospital, UK.
authors.forename: G J
authors.initials: GJ
authors.lastname: Connett
authors.forename: I J
authors.initials: IJ
authors.lastname: Doull
authors.forename: K
authors.initials: K
authors.lastname: Keeping
authors.forename: J O
authors.initials: JO
authors.lastname: Warner
mesh_terms: D000293:Adolescent; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology / Q000382:microbiology; D020680:Bronchoscopes; D001999:Bronchoscopy / Q000379:methods; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications*; D005260:Female; D005336:Fiber Optic Technology; D005764:Gastroesophageal Reflux / Q000150:complications; D006801:Humans; D007223:Infant; D008171:Lung Diseases / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D008297:Male; D016896:Treatment Outcome