Near-optimal sequence alignment.
Recent advances in algorithmic techniques and statistics of sequence alignment have helped to make near-optimal alignments an important tool in the delineation of biologically valid alignments. Near-optimal alignments serve to judge the reliability of portions of a sequence alignment. The statistical assessment of suboptimal alignment scores makes sequence alignments less dependent on gap-penalty choice.
Vingron
M
M
Deutsches Krebsforschungszentrum (DKFZ), Abteilung Theoretische Bioinformatik, Heidelberg, Germany. m.vingron@dkfz-heidelberg.de
D000465:Algorithms; D007140:Immunoglobulin Fab Fragments / Q000737:chemistry; D007135:Immunoglobulin Variable Region / Q000737:chemistry; D011487:Protein Conformation; D016415:Sequence Alignment
D007140:Immunoglobulin Fab Fragments; D007135:Immunoglobulin Variable Region