title: Transdermal drug delivery: useful paradigms.
abstract: The successful development of transdermal delivery systems requires a systematic evaluation and understanding of a number of complex phenomena. For example, the study of drug transport through skin (and other biomembranes) has lead to a significant advance in our ability to select drugs which are appropriate for transdermal delivery. Drug release from the transdermal system is also crucial to effective drug delivery and provides a clear opportunity for research in adhesion, polymer physical chemistry, mass transport, and film coating, to name a few. The incorporation of several disciplines into transdermal science holds the exciting promise to provide rapid advances in this technology.
authors.affiliation: Cygnus Therapeutic Systems, Redwood City, CA 94063, USA.
authors.forename: R O
authors.initials: RO
authors.lastname: Potts
authors.forename: G W
authors.initials: GW
authors.lastname: Cleary
mesh_terms: D000279:Administration, Cutaneous; D000818:Animals; D002626:Chemistry, Pharmaceutical; D006801:Humans; D012867:Skin / Q000737:chemistry / Q000378:metabolism*; D012879:Skin Physiological Phenomena