title: Neuromyotonia and type I myofiber predominance in amyloidosis.
abstract: A case of amyloidosis presented with neurormyotonia and marked predominance of type I myofibers as documented by biopsy of an enlarged anterior tibialis muscle. This likely represents conversion of type II fibers to type I from continuous neuromyotonic stimulation. This transformation is well described to occur in animal models and this case represents a unique human example. Enlarged muscles likely reflected pseudohypertrophy.
authors.affiliation: Department of Neurology, Robert C. Byrd Health Sciences Center, West Virginia University, Morgantown 26506-9180, USA.
authors.forename: L
authors.initials: L
authors.lastname: Gutmann
authors.forename: L
authors.initials: L
authors.lastname: Gutmann
authors.forename: S S
authors.initials: SS
authors.lastname: Schochet
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000150:complications*; D001706:Biopsy; D004576:Electromyography; D005207:Fasciculation / Q000209:etiology* / Q000473:pathology*; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D018485:Muscle Fibers, Skeletal / Q000145:classification / Q000648:ultrastructure*; D018482:Muscle, Skeletal / Q000473:pathology / Q000503:physiopathology