title: Comparison between 2 surgical techniques for the treatment of early-onset periodontitis.
abstract: The objective of this study was to compare guided tissue regeneration (GTR) and osseous surgery (OS) in treatment of early-onset periodontitis. Six patients participated in this research, presenting 15 paired defects randomly assigned to 1 of the surgical groups. Pre-operative clinical parameters (probing depth and attachment loss) between the two groups were not significantly different. Results 1 year following surgery showed probing depth reduction (2.60 +/- 1.30 mm) and clinical attachment gain (2.20 +/- 1.42 mm) were significantly greater in the GTR group than in the osseous surgery group (P < 0.05). The gingival recession was -0.53 +/- 0.52 mm and -0.40 +/- 0.74 mm for the osseous and the guided tissue regeneration group, respectively (no significant difference, P > 0.05). Radiographic analysis by two techniques illustrated that the interproximal alveolar bone changes at the margin of the defects in the OS group were slightly decreased (-0.20 +/- 1.15; 0.26 +/- 0.74 mm) and those in the GTR group were slightly increased (0.16 +/- 0.96; 0.26 +/- 0.68 mm), but showed no significant difference (P > 0.05). The base of the GTR-treated defects showed significant increase in bone fill (1.67 +/- 0.68; 1.97 +/- 0.74 mm; P < 0.05). At a follow-up reexamination 1 year following surgery, oral hygiene and gingival conditions in both groups were at satisfactory levels and gingiva was clinically healthy throughout the entire study period, except the first 4 to 6 weeks following surgery.
authors.affiliation: Department of Oral Medicine and Periodontics, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
authors.forename: M
authors.initials: M
authors.lastname: Sirirat
authors.forename: J
authors.initials: J
authors.lastname: Kasetsuwan
authors.forename: M K
authors.initials: MK
authors.lastname: Jeffcoat
mesh_terms: D000328:Adult; D010520:Aggressive Periodontitis / Q000601:surgery*; D016301:Alveolar Bone Loss / Q000601:surgery*; D005260:Female; D016557:Guided Tissue Regeneration, Periodontal; D006801:Humans; D008297:Male; D008567:Membranes, Artificial; D010512:Periodontal Index; D011138:Polytetrafluoroethylene; D013524:Surgical Flaps; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D008567:Membranes, Artificial; D011138:Polytetrafluoroethylene