Olfactory mechanisms in Drosophila melanogaster.
Genetic approaches are beginning to provide valuable insights into the function of specific gene products in olfaction. Analysis of Drosophila mutants that affect olfactory responses are defining components of the olfactory signaling mechanisms. Mutations in the genes paralytic and Scutoid cause olfactory defects, as do mutations in genes encoding products that mediate visual responses. In addition, members of the family of invertebrate odorant-binding proteins have been identified in Drosophila and may play an important role in the olfactory process.
Smith
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Department of Pharmacology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, 75235-9111, USA. Smith15@utsw.swmed.edu
D000818:Animals; D001696:Biomechanical Phenomena; D004331:Drosophila melanogaster / Q000235:genetics / Q000502:physiology*; D005796:Genes; D009154:Mutation; D009812:Odorants; D009833:Olfactory Pathways / Q000502:physiology; D018035:Receptors, Odorant / Q000378:metabolism; D012678:Sensation Disorders / Q000235:genetics / Q000378:metabolism; D012903:Smell / Q000502:physiology*; D015222:Sodium Channels / Q000235:genetics; D014795:Visual Pathways / Q000502:physiology
D018035:Receptors, Odorant; D015222:Sodium Channels; C045648:odorant-binding protein