title: [Invasive amebiasis at an institution for the mentally retarded in Shizuoka Prefecture].
abstract: Amebiasis caused by Entamoeba histolytica at an institution for mentally retarded in Shizuoka Prefecture is reported. Five of the 50 patients showed E. histolytica cysts in their stools and 4 were positive serologically. The polymerase chain reaction and restriction fragment length polymorphism revealed that the isolates were pathogenic-type E. histolytica. Epidemiological analysis revealed that the amebic infection was caused by the abnormal behavior of mentally retarded patients. Administration of diloxanide furoate and metronidazole for cyst-carriers eliminated cysts from the stool and lowered the antibody titer.
authors.affiliation: Shizuoka Prefectural Institute of Public Health and Environmental Science.
authors.forename: K
authors.initials: K
authors.lastname: Sahara
authors.forename: W
authors.initials: W
authors.lastname: Hori
authors.forename: T
authors.initials: T
authors.lastname: Masuda
authors.forename: K
authors.initials: K
authors.lastname: Ohata
authors.forename: F
authors.initials: F
authors.lastname: Yamazaki
authors.forename: S
authors.initials: S
authors.lastname: Akahane
authors.forename: H
authors.initials: H
authors.lastname: Hattori
authors.forename: H
authors.initials: H
authors.lastname: Yuasa
authors.forename: I
authors.initials: I
authors.lastname: Hashizume
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
authors.forename: K
authors.initials: K
authors.lastname: Nagakura
authors.forename: H
authors.initials: H
authors.lastname: Tachibana
mesh_terms: D000328:Adult; D000818:Animals; D004748:Entamoeba histolytica / Q000302:isolation & purification; D004749:Entamoebiasis / Q000453:epidemiology* / Q000209:etiology / Q000469:parasitology; D005260:Female; D006801:Humans; D007326:Institutionalization; D008607:Intellectual Disability / Q000150:complications*; D007564:Japan / Q000453:epidemiology; D008297:Male