title: Oesophageal carcinoma with humoral hypercalcaemia of malignancy and leucocytosis.
abstract: We report a case of oesophageal carcinoma with humoral hypercalcaemia of malignancy and leucocytosis in a 66-year-old man. We also demonstrate parathyroid hormone-related protein, by immunohistology. After admission, calcitonin was administered for the hypercalcaemia but the patient died of pneumonia on the 17th day of hospitalization. As oesophageal carcinoma with humoral hypercalcaemia of malignancy and leucocytosis is characterized by rapid progression and metastasis, earlier diagnosis and treatment is mandatory.
authors.affiliation: Department of Internal Medicine, Amano Hospital, Tokyo, Japan.
authors.forename: H A
authors.initials: HA
authors.lastname: Watanabe
authors.forename: H
authors.initials: H
authors.lastname: Matsushita
authors.forename: H
authors.initials: H
authors.lastname: Matsui
authors.forename: A
authors.initials: A
authors.lastname: Ishida
authors.forename: S
authors.initials: S
authors.lastname: Taguchi
authors.forename: H
authors.initials: H
authors.lastname: Sata
authors.forename: N
authors.initials: N
authors.lastname: Amano
mesh_terms: D000368:Aged; D002116:Calcitonin / Q000627:therapeutic use; D004938:Esophageal Neoplasms / Q000150:complications* / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy / Q000209:etiology*; D007964:Leukocytosis / Q000209:etiology*; D008113:Liver Neoplasms / Q000556:secondary; D008297:Male; D044162:Parathyroid Hormone-Related Protein; D011506:Proteins / Q000378:metabolism
chemical_list: C470121:PTHLH protein, human; D044162:Parathyroid Hormone-Related Protein; D011506:Proteins; D002116:Calcitonin