Immunity to Lyme disease: protection, pathology and persistence.
Persistence of the Lyme disease spirochete, Borrelia burgdorferi, in the presence of an active immune response has been well documented. Evidence from the past year indicates that modulation of surface antigens by the spirochete may be a major mechanism for evading the immune response.
Seiler
K P
KP
Department of Pathology, University of Utah School of Medicine Salt Lake City, Utah 84132, USA. kathy_seiler@hlthsci.med.utah.edu
Weis
J J
JJ
D000818:Animals; D002353:Carrier State / Q000276:immunology* / Q000473:pathology; D015787:Erythema Chronicum Migrans / Q000276:immunology / Q000473:pathology / Q000517:prevention & control*; D006801:Humans; D007113:Immunity, Innate / Q000276:immunology; D008193:Lyme Disease / Q000276:immunology* / Q000473:pathology* / Q000517:prevention & control; D013997:Time Factors