title: Changes in the surface carbohydrate composition and exposure of anionic groups caused by beta-lactam antibiotics in streptococci.
abstract: Upon the addition of beta-lactam antibiotics at concentrations that caused a 50% reduction in the dry weight, beta-haemolytic streptococci produced increased amount of rhamnose, though the hexosamine content remained unchanged. These sugars are components of C-carbohydrate. Sialic acid content also increased in group B streptococcal surfaces and penicillin treatment generated new accessible surface sialic acid residues.
authors.affiliation: Instituto de Microbiologia, Universidade Federal do Rio de Janeiro, Brazil.
authors.forename: A M
authors.initials: AM
authors.lastname: Figueiredo
authors.forename: B T
authors.initials: BT
authors.lastname: Ferreira-Carvalho
authors.forename: C S
authors.initials: CS
authors.lastname: Alviano
authors.forename: J
authors.initials: J
authors.lastname: Angluster
authors.forename: F C
authors.initials: FC
authors.lastname: Silva Filho
authors.forename: L C
authors.initials: LC
authors.lastname: Benchetrit
mesh_terms: D000838:Anions; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D050260:Carbohydrate Metabolism; D006595:Hexosamines / Q000378:metabolism; D012210:Rhamnose / Q000378:metabolism; D012794:Sialic Acids / Q000378:metabolism; D013292:Streptococcus agalactiae / Q000187:drug effects* / Q000378:metabolism*; D013499:Surface Properties; D047090:beta-Lactams
chemical_list: D000838:Anions; D000900:Anti-Bacterial Agents; D006595:Hexosamines; D012794:Sialic Acids; D047090:beta-Lactams; D012210:Rhamnose