title: [Antihistaminics].
abstract: The antihistamines are drugs who compete for the histamine receptor H-1, blocking the liberation of autacoid mediators, that is the reason for their action in allergic diseases. It's important to know the pharmacodynamics and pharmacokinetics of these drugs in order to choose the best one for the patient, looking for the ones who have less side effects and work better. We show a summary of the principal antihistamines, their actions and side effects.
authors.affiliation: Departamento de neumología y alergia, Hospital Infantil de México Federico Gómez, México, DF.
authors.forename: A
authors.initials: A
authors.lastname: Gazca Aguilar
authors.forename: B
authors.initials: B
authors.lastname: del Rio Navarro
authors.forename: J J
authors.initials: JJ
authors.lastname: Sienra Monge
mesh_terms: D015777:Eicosanoids / Q000378:metabolism; D005767:Gastrointestinal Diseases / Q000139:chemically induced; D006632:Histamine / Q000502:physiology; D006634:Histamine H1 Antagonists / Q000009:adverse effects / Q000145:classification / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D007249:Inflammation / Q000188:drug therapy; D009422:Nervous System Diseases / Q000139:chemically induced; D011969:Receptors, Histamine H1 / Q000187:drug effects / Q000502:physiology; D015398:Signal Transduction / Q000187:drug effects
chemical_list: D015777:Eicosanoids; D006634:Histamine H1 Antagonists; D011969:Receptors, Histamine H1; D006632:Histamine