Transient and permanent neonatal diabetes.
Neonatal diabetes, which may be transient or permanent, is rare. Most patients are full-term but small- for-date infants. Typical symptoms of diabetes mellitus occur within the first 4 weeks of life, requiring insulin therapy and very strict blood glucose monitoring. Subsequent growth and psychomotor development are usually normal. In about 33% of these patients the diabetes remains permanent; the transient cases, however, often develop permanent diabetes mellitus later in life. Exocrine pancreatic insufficiency is present in some patients. Neonatal diabetes differs from type-I diabetes in many aspects and seems to form a distinct entity of inborn pancreatic malfunction.
Fösel
S
S
Kinderklinik, Schweinfurt, Germany.
D017668:Age of Onset; D003922:Diabetes Mellitus, Type 1 / Q000151:congenital / Q000453:epidemiology / Q000209:etiology / Q000276:immunology / Q000628:therapy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006943:Hyperglycemia / Q000151:congenital / Q000209:etiology / Q000276:immunology / Q000628:therapy; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D008297:Male; D010179:Pancreas / Q000276:immunology / Q000503:physiopathology; D013548:Sweden / Q000453:epidemiology; D013997:Time Factors