[Specifics of metabolic disorders in patients with "hormone-associated neoplastic" syndromes].
Overweight, lipidemia features, glucose tolerance and insulinemia were studied in 642 females suffering tumors of the corpus uteri, breast, ovary and large bowel, i.e. types of neoplasia which often occur and correspond to the syndrome of primary multiple "hormone-related" cancers. Beside certain obvious similarities in the said parameters established among patients with the said pathologies, the distinctions related, first of all, to degree of pernicious tumor process and, possibly, preoperative weight loss. Since no differences were found in manifestations of hormono-metabolic disturbances between cases of solitary and primary multiple neoplasms of the same localizations, it is suggested that carcinogenesis of both types might be caused by the same factors.
Rybin
E P
EP
Bershtein
L M
LM
Tsyrlina
E V
EV
Kovalenko
I G
IG
Gamaiunova
V B
VB
Evtushenko
T P
TP
Bokhman
I V
IV
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism; D015992:Body Mass Index; D001943:Breast Neoplasms / Q000378:metabolism; D003110:Colonic Neoplasms / Q000378:metabolism; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D008055:Lipids / Q000097:blood; D008875:Middle Aged; D009376:Neoplasms, Hormone-Dependent / Q000378:metabolism*; D009378:Neoplasms, Multiple Primary / Q000378:metabolism*; D010051:Ovarian Neoplasms / Q000378:metabolism; D014594:Uterine Neoplasms / Q000378:metabolism
D001786:Blood Glucose; D007328:Insulin; D008055:Lipids