title: Factor V Q 506 mutation in children with thrombosis.
abstract: The factor V Leiden mutation in 12-children with thrombosis and in 20 controls was investigated. Five heterozygous individuals and 1 homozygous individual among the cases with thrombosis and 1 heterozygous individual among controls were found. Central nervous system thromboses were increased in children with the factor V mutation, associated with protein S deficiency.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Gurgey
authors.forename: L
authors.initials: L
authors.lastname: Mesci
authors.forename: Y
authors.initials: Y
authors.lastname: Renda
authors.forename: L
authors.initials: L
authors.lastname: Olcay
authors.forename: N
authors.initials: N
authors.lastname: Kocak
authors.forename: G
authors.initials: G
authors.lastname: Erdem
mesh_terms: D016022:Case-Control Studies; D002648:Child; D005165:Factor V / Q000235:genetics*; D005260:Female; D006579:Heterozygote; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009154:Mutation; D018455:Protein S Deficiency / Q000235:genetics; D013927:Thrombosis / Q000235:genetics*
chemical_list: D005165:Factor V