title: Chemokine receptors - the new frontier for AIDS research.
abstract: CD4 is widely known as the HIV receptor, but is insufficient to allow viral infection. Recently, members of the family of chemokine receptors have been identified as the missing co-receptors, which act with CD4 to allow the virus to enter cells. These discoveries open up the possibilities of novel therapeutic strategies to combat HIV infection and AIDS.
authors.affiliation: Geneva Biomedical Research Institute, Glaxo Wellcome Research and Development, 14 Chemin des Aulx, 1228 Plan les Ouates, Geneva, Switzerland.
authors.forename: T N
authors.initials: TN
authors.lastname: Wells
authors.forename: A E
authors.initials: AE
authors.lastname: Proudfoot
authors.forename: C A
authors.initials: CA
authors.lastname: Power
authors.forename: M
authors.initials: M
authors.lastname: Marsh
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000209:etiology* / Q000628:therapy; D000818:Animals; D018925:Chemokines / Q000502:physiology*; D006678:HIV / Q000472:pathogenicity; D006801:Humans; D008024:Ligands; D008565:Membrane Proteins / Q000502:physiology; D051379:Mice; D008954:Models, Biological; D019718:Receptors, CXCR4; D018121:Receptors, Cytokine / Q000502:physiology*; D015728:Receptors, HIV / Q000502:physiology; D012106:Research
chemical_list: D018925:Chemokines; D008024:Ligands; D008565:Membrane Proteins; D019718:Receptors, CXCR4; D018121:Receptors, Cytokine; D015728:Receptors, HIV