IL-4 and IL-13 receptors: are they one and the same?
Interleukin 4 (IL-4) and IL-13 share several biological properties, suggesting that they also share a common receptor or receptor component. Indeed, as discussed here by Robin Callard and colleagues, the IL-13 receptor appears to be a functional receptor for IL-4.
Callard
R E
RE
Immunobiology Unit, Institute of Child Health, London, UK. rcallard@ICH.BPMF.AC.UK
Matthews
D J
DJ
Hibbert
L
L
D000818:Animals; D015703:Antigens, CD / Q000737:chemistry / Q000502:physiology*; D006801:Humans; D053661:Interleukin-13 Receptor alpha1 Subunit; D018123:Receptors, Interleukin / Q000737:chemistry / Q000502:physiology*; D053660:Receptors, Interleukin-13; D019948:Receptors, Interleukin-4; D015398:Signal Transduction
D015703:Antigens, CD; C508181:IL13RA1 protein, human; D053661:Interleukin-13 Receptor alpha1 Subunit; D018123:Receptors, Interleukin; D053660:Receptors, Interleukin-13; D019948:Receptors, Interleukin-4