title: 201TL SPECT for evaluating head and neck cancer.
abstract: BACKGROUND
  Thallium-201 (201Tl) has come to be widely used in diagnosis of several kinds of malignant tumor, but its usefulness in diagnosing head and neck cancer has not been established.
  
  
  OBJECTIVE
  This study investigated the usefulness of 201Tl SPECT imaging in patients with head and neck cancer histologically confirmed.
  
  
  METHODS
  Eighteen patients with histologically proven head and neck cancer were studied. 201Tl SPECT images were obtained both 15 min and 4 hours after intravenous injection of 148 MBq of 201Tl-chloride. 201Tl-indices were calculated semiquantitatively to assess the tracer uptake in relation to tumor size and histological type.
  
  
  RESULTS
  High 201Tl uptake was noted in all primary tumors and metastatic lymph nodes on the both early and delayed images, but 201Tl-indices did not show any correlation with tumor size or histological type.
  
  
  CONCLUSIONS
  Primary had and neck cancer and lymph node metastasis can be effectively visualized with 201Tl SPECT. It may provide information in addition to morphological changes and may be supplemental method to use in the evaluation of head and neck cancer.
authors.affiliation: Department of Radiology, Miyazaki Medical College, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Nagamachi
authors.forename: H
authors.initials: H
authors.lastname: Hoshi
authors.forename: S
authors.initials: S
authors.lastname: Jinnouchi
authors.forename: T
authors.initials: T
authors.lastname: Ohnishi
authors.forename: L G
authors.initials: LG
authors.lastname: Flores
authors.forename: S
authors.initials: S
authors.lastname: Futami
authors.forename: H
authors.initials: H
authors.lastname: Nakahara
authors.forename: K
authors.initials: K
authors.lastname: Watanabe
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary; D005260:Female; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D014057:Tomography, X-Ray Computed
chemical_list: D013794:Thallium Radioisotopes