title: The ubiquitin-mediated proteolytic system: involvement of molecular chaperones, degradation of oncoproteins, and activation of transcriptional regulators.
authors.affiliation: The Department of Biochemistry, Faculty of Medicine, Technion-Israel Institute of Technology, Haifa.
authors.forename: A
authors.initials: A
authors.lastname: Ciechanover
authors.forename: A
authors.initials: A
authors.lastname: Laszlo
authors.forename: B
authors.initials: B
authors.lastname: Bercovich
authors.forename: I
authors.initials: I
authors.lastname: Stancovski
authors.forename: I
authors.initials: I
authors.lastname: Alkalay
authors.forename: Y
authors.initials: Y
authors.lastname: Ben-Neriah
authors.forename: A
authors.initials: A
authors.lastname: Orian
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism*; D050883:HSC70 Heat-Shock Proteins; D018840:HSP70 Heat-Shock Proteins; D020672:I-kappa B Proteins; D066298:In Vitro Techniques; D008954:Models, Biological; D018832:Molecular Chaperones / Q000378:metabolism*; D000072000:NF-KappaB Inhibitor alpha; D016328:NF-kappa B / Q000378:metabolism; D015513:Oncogene Proteins / Q000378:metabolism*; D016760:Proto-Oncogene Proteins c-fos / Q000378:metabolism; D016755:Proto-Oncogene Proteins c-jun / Q000378:metabolism; D011817:Rabbits; D012156:Reticulocytes / Q000378:metabolism; D015533:Transcriptional Activation; D014452:Ubiquitins / Q000378:metabolism*
chemical_list: D002352:Carrier Proteins; D004268:DNA-Binding Proteins; D050883:HSC70 Heat-Shock Proteins; D018840:HSP70 Heat-Shock Proteins; D020672:I-kappa B Proteins; D018832:Molecular Chaperones; D016328:NF-kappa B; D015513:Oncogene Proteins; D016760:Proto-Oncogene Proteins c-fos; D016755:Proto-Oncogene Proteins c-jun; D014452:Ubiquitins; D000072000:NF-KappaB Inhibitor alpha; D010450:Endopeptidases