title: Directed TOCSY, a method for selection of directed correlations by optimal combinations of isotropic and longitudinal mixing.
abstract: The directed TOCSY pulse sequence element transfers coherence predominantly into "forward-directed" antiphase coherences while simultaneously suppressing in-phase and "backward-directed" antiphase coherences. This novel selection principle, based on the "direction" of the target coherences, provides a new approach for the simplification of crowded spectra. In this article, the theory of directed TOCSY is presented for linear spin systems that are frequently found in carbon-labeled biomolecules.
authors.affiliation: Institut für Organische Chemie, Universität Frankfurt, Marie-Curie-Strasse 11, Frankfurt, D-60439, Germany.
authors.forename: S J
authors.initials: SJ
authors.lastname: Glaser
authors.forename: H
authors.initials: H
authors.lastname: Schwalbe
authors.forename: J P
authors.initials: JP
authors.lastname: Marino
authors.forename: C
authors.initials: C
authors.lastname: Griesinger
mesh_terms: D008279:Magnetic Resonance Imaging / Q000379:methods*; D008433:Mathematics; D009841:Oligonucleotides / Q000032:analysis; D012313:RNA / Q000032:analysis
chemical_list: D009841:Oligonucleotides; D012313:RNA