[Breast-preserving (conservative) therapy of breast cancer].
Conservative surgery (sectoral or segmental + axillary dissection) was performed in 278 patients with breast cancer (T1-2N0M0) at the Institute Clinic in 1990-1995. Following thorough morphological examination. 148 patients (53.2%) were selected to form a clinical study group for an investigation of the role of postoperative radiotherapy in the conservative treatment of breast cancer. Two groups-irradiation of the remaining breast tissue and controls-were formed on the basis of randomized data. Follow-up continued 3-60 months (average duration-37.7 months). Local recurrence was detected in 3 out of 73 (4.2%) patients of group I. A similar relapse was detected in 6 out of 75 (8.0%) patients of group II. No significant difference in total survival rates in the two groups was observed (97.3 and 96.0%; p > 0.05).
Semiglazov
V F
VF
Kanaev
S V
SV
Chagunava
O L
OL
Ivanova
O A
OA
Pozharisskiĭ
K M
KM
Chepik
O F
OF
Vesnin
A G
AG
Zaĭtsev
A N
AN
Orlov
A A
AA
Krinitsina
N N
NN
Barash
N I
NI
Seleznev
I K
IK
Migmanova
N S
NS
Popova
R T
RT
Ivanov
V G
VG
Golubeva
O M
OM
Bozhok
A A
AA
D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D005260:Female; D006801:Humans; D015412:Mastectomy, Segmental; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D018714:Radiotherapy, Adjuvant; D016019:Survival Analysis; D016896:Treatment Outcome