title: [Kinetic study of the cyclization of the addition compound of ethyl mercaptoacetate on benzylideneacetophenone].
abstract: The study of the kinetic of cyclisation reaction of the additional compound of the mercaptoacetic ethylester on a benzylideneacetophenone was proposed. With the chromatography a retro-Michael reaction was obtained. The H NMR alone permitted to show the order 1 for the kinetic of cyclization and according to the amine used like reaction catalyst, two diastereoisomers could be formed.
authors.affiliation: Equipe de Chimie Thérapeutique, UFR des Sciences, Médicales et Pharmaceutiques, Besançon.
authors.forename: C
authors.initials: C
authors.lastname: Guinchard
authors.forename: A
authors.initials: A
authors.lastname: Dankar
authors.forename: M F
authors.initials: MF
authors.lastname: Mercier
authors.forename: A
authors.initials: A
authors.lastname: Xicluna
authors.forename: J F
authors.initials: JF
authors.lastname: Robert
mesh_terms: D002599:Chalcone / Q000008:administration & dosage / Q000493:pharmacokinetics*; D002851:Chromatography, High Pressure Liquid; D003500:Cyclization; D004338:Drug Combinations; D066298:In Vitro Techniques; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013237:Stereoisomerism; D013864:Thioglycolates / Q000008:administration & dosage / Q000493:pharmacokinetics*
chemical_list: D004338:Drug Combinations; D013864:Thioglycolates; D002599:Chalcone; C017487:2-mercaptoacetate