Alpha 1-antitrypsin deficiency alleles and blood pressure in an Australian population.
1. Two deficiency alleles of alpha 1-antitrypsin (AAT) called S and Z have been previously associated with lower blood pressure levels. 2. A sample of Australian hypertensive and normotensive subjects was investigated with respect to these alleles. 3. No association of blood pressure levels with these AAT alleles was found in our study sample.
Huggard
P R
PR
Department of Medicine, University of Queensland, Prince Charles Hospital, Chermside, Australia.
West
M J
MJ
Summers
K M
KM
D000483:Alleles; D001315:Australia / Q000453:epidemiology; D001794:Blood Pressure / Q000235:genetics*; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D005819:Genetic Markers; D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000235:genetics; D016133:Polymerase Chain Reaction; D044465:White People; D000515:alpha 1-Antitrypsin / Q000235:genetics*; D019896:alpha 1-Antitrypsin Deficiency
D005819:Genetic Markers; D000515:alpha 1-Antitrypsin; D004247:DNA