title: Serum lidocaine concentrations after subcutaneous administration in patients undergoing cardiac catheterization in a pediatric institution.
abstract: OBJECTIVE
  We wished to determine serum lidocaine concentrations after subcutaneous injection during cardiac catheterization.
  
  
  METHODS
  Serum lidocaine concentrations were measured in 50 patients during catheterization.
  
  
  RESULTS
  Serum concentration was linearly related to dose per kilogram of body weight. Lidocaine concentrations were therapeutic in 38% of patients.
  
  
  CONCLUSIONS
  Lidocaine dose must be considered when the drug is used for local anesthesia in children.
authors.affiliation: Department of Pediatrics, Ohio State University, Columbus, USA.
authors.forename: S C
authors.initials: SC
authors.lastname: Cassidy
authors.forename: P R
authors.initials: PR
authors.lastname: Jones
authors.forename: S
authors.initials: S
authors.lastname: Cox
authors.forename: P D
authors.initials: PD
authors.lastname: Walson
authors.forename: H D
authors.initials: HD
authors.lastname: Allen
mesh_terms: D000779:Anesthetics, Local / Q000008:administration & dosage / Q000493:pharmacokinetics*; D006328:Cardiac Catheterization; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007279:Injections, Subcutaneous; D008012:Lidocaine / Q000008:administration & dosage / Q000097:blood* / Q000493:pharmacokinetics
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine