title: [Social outcome of 20 anterior callosotomies for drug-resistant epilepsy].
abstract: Results of 20 anterior callosotomies with regard to quality of life and social outcome were analysed according to seizure control. Data arise from a retrospective study with the medico-social teams. Drop attacks with tonic or atonic seizures decreased in 11 cases. Nevertheless only 8 cases (40%) have experienced a reduction of more than 70% in seizure frequency. Neurocognitive status slightly worsened in 3 cases. Age at intervention and type of epileptic syndrome were not predictors of seizure outcome. A subjective improvement in quality of life was reported in 10 cases. A significant improvement in social adjustment was obtained in 7 cases (35%). There was a close correlation between life comfort improvement and reduction in drop attack frequency. Not only seizure control has to be better but also surgery must be performed sooner to obtain a gain in social independence. Finally, successful outcome should be considered as limited. Nevertheless results may be considered taking into account the high severity of the condition and the low morbidity of anterior callosotomy.
authors.affiliation: Service de Neurochirurgie, CHU Pellegrin, Bordeaux.
authors.forename: A
authors.initials: A
authors.lastname: Rougier
authors.forename: B
authors.initials: B
authors.lastname: Claverie
authors.forename: C
authors.initials: C
authors.lastname: Marchal
authors.forename: J M
authors.initials: JM
authors.lastname: Pedespan
authors.forename: P
authors.initials: P
authors.lastname: Loiseau
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000927:Anticonvulsants / Q000627:therapeutic use; D002648:Child; D003337:Corpus Callosum / Q000601:surgery*; D004351:Drug Resistance; D004828:Epilepsies, Partial / Q000188:drug therapy / Q000523:psychology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D011788:Quality of Life; D012189:Retrospective Studies; D012917:Social Adjustment
chemical_list: D000927:Anticonvulsants