title: [The results of cytogenetic studies of workers in industrial enterprises].
abstract: Cytogenetic monitoring of workers of large industrial enterprizes showed the presence of chromatide aberrations in the peripheral blood lymphocytes, which were more manifest in workers of chemical and byproduct cokeplants, and somewhat less apparent in metallurgists. The frequency of metaphases involving chromosomal aberrations is dependent upon the duration of occupational exposure to chemical mutagens. However, the number of chromosomal abberrations does not appear to be influenced by chemical factors remaining essantially the same. The human embrion genome sensitivity to the chemical mutagen action was found to be much higher than that of somatic cells of the adults occupationally exposed to alterating factors. Use of complexes of antioxidants (tocopheroli acetas, quercetin, splenin) makes for reduction in the number of chromosomal aberrations in workers engaged in chemical industry.
authors.forename: I R
authors.initials: IR
authors.lastname: Baryliak
authors.forename: V M
authors.initials: VM
authors.lastname: Frolov
authors.forename: M O
authors.initials: MO
authors.lastname: Peresadin
authors.forename: V Ia
authors.initials: VIa
authors.lastname: Vytrishchak
authors.forename: L Ie
authors.initials: LIe
authors.lastname: Koval'chuk
mesh_terms: D000328:Adult; D002617:Chemical Industry; D002869:Chromosome Aberrations / Q000235:genetics*; D003077:Coke; D006801:Humans; D008669:Metallurgy; D008677:Metaphase; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects* / Q000706:statistics & numerical data; D013997:Time Factors; D014455:Ukraine
chemical_list: D003077:Coke