title: Severe spontaneous carotid artery dissection and multiple aneurysmal dilatations. A case report.
abstract: Spontaneous cervical artery dissections or arterial aneurysms associated with deficiencies of alpha(1)-antitrypsin (alpha(1)-AT) or other inhibitors of proteolytic enzymes have occasionally been reported. However, a coexistence of severe spontaneous internal carotid artery dissection and multiple aneurysmal dilatations associated with alpha(1)-AT phenotype M1S have not yet been presented; herein the authors describe such a patient. In order to avoid the risks associated with intraarterial angiography in a patient in whom an underlying arteriopathy is suspected, only noninvasive techniques were employed. This case demonstrates that magnetic resonance imaging combined with magnetic resonance angiography is a valuable noninvasive method for use in diagnosis and follow-up of carotid artery dissection.
authors.affiliation: Max Planck Institute of Psychiatry, Clinical Institute, Neurology, Munich, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Plaschke
authors.forename: D
authors.initials: D
authors.lastname: Auer
authors.forename: T
authors.initials: T
authors.lastname: Trapp
authors.forename: P
authors.initials: P
authors.lastname: Trenkwalder
authors.forename: C
authors.initials: C
authors.lastname: Trenkwalder
mesh_terms: D000783:Aneurysm / Q000175:diagnosis*; D000784:Aortic Dissection / Q000175:diagnosis; D002340:Carotid Artery Diseases / Q000175:diagnosis*; D002343:Carotid Artery, Internal; D006801:Humans; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D019896:alpha 1-Antitrypsin Deficiency