The thalamic commissure in generalized epilepsy.
In selected patients callosotomy usually dramatically improves disabling generalized epilepsy, but it also may be without any effect. This paradox might be due to the anatomical variability of the thalamic commissure, which interconnects thalamic nuclei essential to the dynamics of seizures. The commissure may be as thick as a finger or absent.
Heick
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Department of Neurology, Glostrup University Hospital, Copenhagen, Denmark.
D000818:Animals; D001931:Brain Mapping; D002415:Cats; D003337:Corpus Callosum / Q000503:physiopathology / Q000601:surgery*; D004292:Dominance, Cerebral / Q000502:physiology; D004829:Epilepsy, Generalized / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D009435:Synaptic Transmission / Q000502:physiology; D013787:Thalamic Nuclei / Q000503:physiopathology / Q000601:surgery*