Cerebrospinal fluid purine metabolites after complex febrile convulsions.
Adenosine monophosphate, inosine monophosphate, inosine, adenosine, guanosine, adenine, guanine, hypoxanthine, xanthine and uric acid were determined in cerebrospinal fluid (CSF) of 15 children after complex febrile seizures (CFS) and in 27 after simple febrile seizures (SFS), and compared with those in a control group of 63 children. There was no statistically significant difference between the groups for any of these metabolites, suggesting that CFS and SFS neither significantly disturb the metabolism of nucleotides, nucleosides or bases nor significantly deplete neuron adenosine triphosphate levels.
Castro-Gago
M
M
Departamento de Pediatría, Hospital General de Galicia, Santiago de Compostela, Spain.
Rodríguez-Segade
S
S
Camiña Darriba
F
F
Cid Fernández
E
E
Eirís Puñal
J
J
Pavón Belinchón
P
P
Rodríguez-Nuñez
A
A
D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011687:Purines / Q000134:cerebrospinal fluid* / Q000378:metabolism; D003294:Seizures, Febrile / Q000134:cerebrospinal fluid* / Q000150:complications
D011687:Purines