title: Cancers of skin, bone, connective tissues, brain, eye, thyroid and other specified and unspecified sites in Inuit.
abstract: Low rates of skin cancer, both melanoma and non-melanoma, were observed in Inuit after 20 years of observation. Tumours of the brain and central nervous system, of the thyroid, bone and connective tissues and other specified sites occurred with rates similar to those in comparison populations in Denmark, Connecticut and Canada. These findings support that neither UV and ionizing radiation from nuclear fall-out, nor pollution of herbicides and pesticides in the Arctic area have yet had any noticeable impact on cancer risk. However, unspecified and secondary neoplasms constitute 7-8% of the total Circumpolar cancer incidence and the pattern of rare cancers must be interpreted with caution. Increased diagnostic efforts with a higher precision in the future are warranted.
authors.affiliation: Department of Preventive Medicine and Biostatistics, Faculty of Medicine, University of Toronto, Ontario, Canada.
authors.forename: A B
authors.initials: AB
authors.lastname: Miller
authors.forename: L A
authors.initials: LA
authors.lastname: Gaudette
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000413:Alaska / Q000453:epidemiology / Q000208:ethnology; D001110:Arctic Regions / Q000453:epidemiology / Q000208:ethnology; D001859:Bone Neoplasms / Q000453:epidemiology / Q000208:ethnology; D002170:Canada / Q000453:epidemiology / Q000208:ethnology; D016543:Central Nervous System Neoplasms / Q000453:epidemiology / Q000208:ethnology; D002648:Child; D002675:Child, Preschool; D003240:Connective Tissue Diseases / Q000453:epidemiology / Q000208:ethnology; D005260:Female; D006116:Greenland / Q000453:epidemiology / Q000208:ethnology; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D004930:Inuit / Q000706:statistics & numerical data*; D008297:Male; D008545:Melanoma / Q000453:epidemiology / Q000208:ethnology; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology* / Q000208:ethnology; D017678:Sex Distribution; D012878:Skin Neoplasms / Q000453:epidemiology / Q000208:ethnology; D013964:Thyroid Neoplasms / Q000453:epidemiology / Q000208:ethnology