title: [Use of enterosorption in biliary tract cancers complicated with mechanical jaundice].
abstract: Enterosorption using polyphepan in experimental mechanical jaundice was followed by improvement of the course of the disease, lower mortality and improvement in endotoxemia indices. The therapeutic effect of enterosorption is due to enhanced transfer of metabolites and toxins through the intestinal wall and subsequent excretion via the gastrointestinal tract. Enterosorption performed in 60 patients with malignancies of the bile tracts and mechanical jaundice was followed by a more rapid improvement in general condition and reduction in the indices of endotoxemia, as compared with 60 controls. Postoperative complication frequency and mortality showed a significant decrease.
authors.forename: E G
authors.initials: EG
authors.lastname: Topuzov
authors.forename: N A
authors.initials: NA
authors.lastname: Beliakov
authors.forename: M M
authors.initials: MM
authors.lastname: Malachev
authors.forename: A K
authors.initials: AK
authors.lastname: Umerov
authors.forename: A V
authors.initials: AV
authors.lastname: Solomennikov
authors.forename: I V
authors.initials: IV
authors.lastname: Gritsenko
authors.forename: A A
authors.initials: AA
authors.lastname: Kokaia
mesh_terms: D000818:Animals; D001661:Biliary Tract Neoplasms / Q000150:complications* / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D002779:Cholestasis / Q000209:etiology*; D016061:Enterosorption; D006801:Humans; D051381:Rats; D016019:Survival Analysis; D016896:Treatment Outcome