[The immune status of patients with acute inflammatory diseases of adnexa uteri associated with different combinations of microorganisms].
The immune status of 130 patients with acute inflammatory diseases of uterine appendages was studied. As etiologically associated infective agents detected in these patients were opportunistic microorganisms (group 1), Neisseria gonorrhoeae in combination with opportunistic microorganisms (group 2) and Chlamydia trachomatis in combination with opportunistic microorganisms (group 3). In all three groups of patients the response of T lymphocytes to PHA and hyperactivation of the B-cell element of immunity (an increase in the relative number of B-lymphocytes and the content of IgA and IgM in the serum) was found to be suppressed. In addition, in groups 1 and 3 an increase, and in group 2 a decrease in IgG were detected. In the mucus of the cervical canal in the patients of groups 1, 2 and 3 IgM was detected, while in patients of groups 2 and 3 a decrease in sigA was established.
Antonova
L V
LV
Medical University, Gamaleya Research Institute of Epidemiology and Microbiology, Moscow, Russia.
Prozorovkaia
K N
KN
Semenova
I B
IB
Shatkin
A A
AA
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood; D002690:Chlamydia Infections / Q000276:immunology / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000276:immunology; D005260:Female; D006069:Gonorrhea / Q000276:immunology / Q000382:microbiology; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000032:analysis; D007153:Immunologic Deficiency Syndromes / Q000276:immunology / Q000382:microbiology; D008875:Middle Aged; D009344:Neisseria gonorrhoeae / Q000276:immunology; D009894:Opportunistic Infections / Q000276:immunology / Q000382:microbiology; D000292:Pelvic Inflammatory Disease / Q000276:immunology* / Q000382:microbiology
D000907:Antibodies, Bacterial; D007136:Immunoglobulins