title: [Time series in the epidemiology of typhoid fever in Spain].
abstract: BACKGROUND
  The incidence of typhoid fever in Spain from January 1982 to December 1993 was studied with the aim of analyzing how the disease has evolved over these years and predict its future behavior in order to facilitate prevention by the public health care organizations and centers.
  
  
  METHODS
  The Box-Jenkins temporary series theory was used. The data corresponded to the declared disease cases throughout Spain published in the Epidemiology Bulletin by the Carlos III Health Center and the Department of Health and Welfare.
  
  
  RESULTS
  The ARIMA (0,1,1) (0,1,1)12 model was selected to report the data obtained. The analytical results demonstrated a exponential decreasing tendency with an annual seasonal pattern in incidence observed in this disease peaking in the months of July, August and September and decreasing in the declared cases in December, January and February. A mathematical expression was also obtained to allow the prediction of the disease behavior in the future.
  
  
  CONCLUSIONS
  Prophylactic measures should be taken in the summer months. A disease incidence greater than that foreseen by the mathematical formula obtained would express a failure in epidemiologic surveillance, and thus the results of this study may be used as a quality control of the preventive measures.
authors.affiliation: Departamento de Estadística, Facultad de Biología, Universidad de Barcelona.
authors.forename: M
authors.initials: M
authors.lastname: Ríos
authors.forename: J M
authors.initials: JM
authors.lastname: García
authors.forename: M
authors.initials: M
authors.lastname: Cubedo
authors.forename: D
authors.initials: D
authors.lastname: Pérez
mesh_terms: D006801:Humans; D015994:Incidence; D008962:Models, Theoretical; D013030:Spain / Q000453:epidemiology; D013223:Statistics as Topic / Q000379:methods; D014435:Typhoid Fever / Q000453:epidemiology*