Fixed drug eruption of the scrotum due to hydroxyzine hydrochloride (Atarax).
Fixed drug eruption describes a sharply localized dermatitis that characteristically recurs at the same site each time the offending drug is administered. Several drugs have been reported to cause this eruption, such as phenolphthalein, barbiturates, penicillin, and others. In this report, two children with fixed drug eruption of the scrotum due to hydroxyzine hydrochloride (Atarax) are described. To the best of our knowledge, no such cases have been reported previously in children.
Cohen
H A
HA
Department of Pediatrics, Hasharon Hospital, Petach Tikvah, Israel.
Cohen
Z
Z
Frydman
M
M
D014151:Anti-Anxiety Agents / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology*; D004487:Edema / Q000139:chemically induced; D004890:Erythema / Q000139:chemically induced; D005832:Genital Diseases, Male / Q000139:chemically induced; D006801:Humans; D006919:Hydroxyzine / Q000009:adverse effects*; D006993:Hypnotics and Sedatives / Q000009:adverse effects*; D007223:Infant; D008263:Macrophage Migration-Inhibitory Factors / Q000009:adverse effects; D008297:Male; D011595:Psychomotor Agitation / Q000188:drug therapy; D012611:Scrotum / Q000187:drug effects*
D014151:Anti-Anxiety Agents; D006993:Hypnotics and Sedatives; D008263:Macrophage Migration-Inhibitory Factors; D006919:Hydroxyzine