Paraproteins and plasma cell dyscrasias.
Serum protein electrophoresis done on 1100 patients with various diseases in one year demonstrated M-band in 31 patients. Most (87%) had the classical features of plasma cell dyscrasia (PCD), however a few had unusual presentations which are highlighted. A 22-year-old male operated for a massive tumour of the scapula clinically diagnosed as chondrosarcoma revealed plasmacytoma with amyloid on histology. Another case of kala-azar presented with features akin to that of PCD and one case had dual malignancies. Such a high incidence of PCDs with varied picture in a short time is not usually seen in other parts of this country; a fact which may be due to lack of awareness.
Karmakar
T
T
Department of Pathology, Post Graduate Institute of Medical Education and Research, Chandigarh.
Datta
U
U
Varma
S
S
Banerjee
C K
CK
Sharma
S
S
Sehgal
S
S
D000328:Adult; D001797:Blood Protein Electrophoresis; D004590:Electrophoresis, Paper; D005260:Female; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010265:Paraproteinemias / Q000175:diagnosis*; D010266:Paraproteins / Q000032:analysis*
D010266:Paraproteins