Association between HLA antigens and early onset periodontitis.
HLA-A, B, C and DR antigen frequencies were determined in a group of patients with juvenile periodontitis and rapidly progressive periodontitis. In juvenile periodontitis patients, HLA-A24 and DR4 were found at a significantly higher level than in the control group, and in rapidly progressive periodontitis patients, A9 and DR4 were found at a significantly higher level than the control group. The presence of these antigens gives evidence as to the susceptibility of various forms of early onset periodontitis.
Firatli
E
E
Department of Periodontology, School of Dentistry, University of Istanbul, Turkey.
Kantarci
A
A
Cebeci
I
I
Tanyeri
H
H
Sönmez
G
G
Carin
M
M
Tuncer
O
O
D000293:Adolescent; D000328:Adult; D010520:Aggressive Periodontitis / Q000276:immunology*; D004198:Disease Susceptibility / Q000276:immunology; D005260:Female; D006680:HLA Antigens / Q000032:analysis*; D015234:HLA-A Antigens / Q000032:analysis; D059871:HLA-A24 Antigen; D015235:HLA-B Antigens / Q000032:analysis; D015236:HLA-C Antigens / Q000032:analysis; D006684:HLA-DR Antigens / Q000032:analysis; D015804:HLA-DR4 Antigen / Q000032:analysis; D006801:Humans; D008297:Male; D010518:Periodontitis / Q000276:immunology*
D006680:HLA Antigens; D015234:HLA-A Antigens; D059871:HLA-A24 Antigen; C037709:HLA-A9 antigen; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D006684:HLA-DR Antigens; D015804:HLA-DR4 Antigen