title: Lessons learned from the DIASTAT vascular access graft.
abstract: BACKGROUND
  The vascular community continues to search for the ideal vascular access graft that will allow early cannulation and avoid temporary central venous catheters.
  
  
  METHODS
  This is a review of the Cranley Surgical Associates' experience with the use of the Gore-Tex DIASTAT (W.L. Gore & Associates, Inc., Flagstaff, Arizona) vascular access graft in 20 patients compared with 20 control patients matched for age, sex and risk factors.
  
  
  RESULTS
  Although the DIASTAT graft is touted for early accessibility and decreased need for central venous access, that was not found to be the case as 14 patients in the DIASTAT group received temporary access catheters. There was significantly more edema in the DIASTAT patients (P = 0.0048). Comparing the time to the first thrombosis or to revision revealed an average of 18 weeks for the DIASTAT group and 56 weeks for the control group. The length of time to thrombosis or revision was significantly longer in the control group (P = 0.0058). Comparison of the number of weeks of function and serviceability of the grafts revealed the average DIASTAT graft functioned for 34 weeks and that of the control group for an average of 70 weeks (P = 0.0131). Comparison of the two groups showed a significant increase in early thrombotic events (< 90 days) in the DIASTAT grafts (P = 0.0013).
  
  
  CONCLUSIONS
  The DIASTAT vascular access graft does not appear to be the ideal hemodialysis access graft.
authors.affiliation: John J. Cranley Vascular Laboratory, Good Samaritan Hospital, Cincinnati, Ohio 45220-2489, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Lohr
authors.forename: K V
authors.initials: KV
authors.lastname: James
authors.forename: A T
authors.initials: AT
authors.lastname: Hearn
authors.forename: S A
authors.initials: SA
authors.lastname: Ogden
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001807:Blood Vessel Prosthesis / Q000009:adverse effects* / Q000295:instrumentation*; D005260:Female; D006801:Humans; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000209:etiology; D006435:Renal Dialysis / Q000379:methods; D012189:Retrospective Studies; D013927:Thrombosis / Q000209:etiology; D013997:Time Factors
chemical_list: D011138:Polytetrafluoroethylene