Predicting the structure of protein complexes: a step in the right direction.
In a blind test of protein-docking algorithms, six groups used different methods to predict the structure of a protein complex. All six predicted structures were close enough to the experimental complex to be useful; nevertheless, several important details of the experimental complex were missed or only partially predicted.
Shoichet
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BK
Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Medical School, 303 E. Chicago Avenue, Chicago, IL 60611-3008, USA.
Kuntz
I D
ID
D000465:Algorithms; D008958:Models, Molecular; D011487:Protein Conformation