Sickle cell thalassemia in pregnancy: a case report.
A 31-year-old pregnant woman at 20 weeks' gestation was sent to our hospital for fever, anemia, and arthralgias. As she was known to be a double heterozygote for beta-thalassemia and hemoglobin S, a diagnosis of hemolytic anemia caused by sickled red cells vasocclusive crises was made. The patient was submitted to partial exchange transfusion (PET) with a complete recovery. A second PET was performed at 36 weeks' gestation, and elective cesarean section was performed at 37 weeks, with the birth of a normal female neonate.
Carpani
G
G
Transfusion Unit, Ospedale San Paolo, University of Milan, Italy.
Bozzetti
P
P
Cetin
I
I
Tel
A
A
Moroni
G A
GA
D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications / Q000175:diagnosis* / Q000235:genetics; D001663:Bilirubin / Q000097:blood; D015415:Biomarkers / Q000097:blood; D005078:Exchange Transfusion, Whole Blood / Q000592:standards; D005260:Female; D006451:Hemoglobin, Sickle / Q000235:genetics; D006454:Hemoglobins / Q000032:analysis; D006579:Heterozygote; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000175:diagnosis* / Q000628:therapy; D011256:Pregnancy Outcome; D017086:beta-Thalassemia / Q000150:complications / Q000175:diagnosis* / Q000235:genetics
D015415:Biomarkers; D006451:Hemoglobin, Sickle; D006454:Hemoglobins; D007770:L-Lactate Dehydrogenase; D001663:Bilirubin