Selective modulation of T-cell responses in autoimmunity and cancer.
Autoreactive T cells are a feature of the normal immune repertoire and can be involved either in prevention or promotion of immunopathology. As discussed at a recent workshop, understanding the nature of this balance is an essential step in developing relevant clinical strategies.
Ottenhoff
T H
TH
Dept of Immunohematology and Bloodbank, University Hospital, Leiden, The Netherlands.
D000818:Animals; D015551:Autoimmunity; D006801:Humans; D008213:Lymphocyte Activation; D009369:Neoplasms / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*