title: Interleukin-11 (IL-11) and its receptor: biology and potential clinical applications in thrombocytopenic states.
authors.affiliation: Department of Medicine, Indiana University School of Medicine, Indianapolis 46202, USA.
authors.forename: Y C
authors.initials: YC
authors.lastname: Yang
mesh_terms: D000818:Animals; D001483:Base Sequence; D001854:Bone Marrow Cells; D016026:Bone Marrow Transplantation; D002986:Clinical Trials as Topic; D004920:Erythropoiesis / Q000187:drug effects; D005260:Female; D005347:Fibroblasts / Q000378:metabolism; D005786:Gene Expression Regulation / Q000502:physiology; D006410:Hematopoiesis / Q000187:drug effects / Q000502:physiology; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D017370:Interleukin-11 / Q000235:genetics / Q000494:pharmacology / Q000502:physiology* / Q000627:therapeutic use; D053703:Interleukin-11 Receptor alpha Subunit; D008533:Megakaryocytes / Q000187:drug effects; D051379:Mice; D008954:Models, Biological; D008969:Molecular Sequence Data; D010010:Osteoclasts / Q000187:drug effects; D010749:Phosphoprotein Phosphatases / Q000235:genetics / Q000378:metabolism; D010766:Phosphorylation; D011323:Primates; D011499:Protein Processing, Post-Translational; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D051381:Rats; D018123:Receptors, Interleukin / Q000737:chemistry / Q000187:drug effects / Q000235:genetics / Q000502:physiology; D053702:Receptors, Interleukin-11; D015398:Signal Transduction / Q000502:physiology; D013921:Thrombocytopenia / Q000628:therapy*; D014407:Tumor Cells, Cultured / Q000187:drug effects
chemical_list: C508428:IL11RA protein, human; C508429:Il11ra1 protein, mouse; C508430:Il11ra1 protein, rat; D007155:Immunologic Factors; D017370:Interleukin-11; D053703:Interleukin-11 Receptor alpha Subunit; D018123:Receptors, Interleukin; D053702:Receptors, Interleukin-11; D011505:Protein-Tyrosine Kinases; D010749:Phosphoprotein Phosphatases