title: [Hematogenic bacterial endophthalmitis. A rare infection with very poor functional prognosis].
abstract: Three men and one woman (mean age 52 years) were admitted to hospital for septicemia (2 cases), sudden partial loss of visual acuity (1 case) and suspected conjunctivitis (1 case). Three of the patients showed risk factors (diabetes, alcohol intoxication, immunosuppression). Panophthalmitis (affecting all tunics of the eye) was apparent from the initial examination in all 4 cases (2 bilateral and 2 unilateral). Ocular involvement was associated with endocarditis and meningitis (pneumococcus) in 1 case, with nocardiosis (pulmonary, cerebral and nodal) in 1 case, and with septicemia with bacterial arthritis (Escherichia coli, streptococcus A) in 2 cases. Hemocultures were positive in 3/4 cases. The micro-organism was also detected in the joint (n = 2), urine (n = 1) and cerebrospinal fluid (n = 1), during pulmonary transparietal puncture (n = 1) and in intraocular biopsy tissue (n = 1). All patients received appropriate antibiotic therapy intravenously and intraocularly. The infection was cured in all cases, but with severe functional sequelae: blindness in 2 cases, and unilateral enucleation in the other 2 cases.
authors.affiliation: Service de Médecine Interne, CHU, Hôtel-Dieu, Nates.
authors.forename: G
authors.initials: G
authors.lastname: Magadur-Joly
authors.forename: F
authors.initials: F
authors.lastname: Raffi
authors.forename: P
authors.initials: P
authors.lastname: Bouchut
authors.forename: P
authors.initials: P
authors.lastname: Chevalet
authors.forename: D
authors.initials: D
authors.lastname: Merrien
authors.forename: L
authors.initials: L
authors.lastname: Struillou
authors.forename: J H
authors.initials: JH
authors.lastname: Barrier
mesh_terms: D000328:Adult; D000368:Aged; D016470:Bacteremia / Q000150:complications* / Q000188:drug therapy; D009877:Endophthalmitis / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D011379:Prognosis