title: Angiographic and duplex grading of internal carotid stenosis: can we overcome the confusion?
abstract: The stroke risk reduction benefit of surgical intervention in carotid occlusive disease has been validated in multicenter trials for various angiographically defined lesion severity categories. The two divergent angiographic grading methods used for internal carotid artery stenosis in these trials have caused confusion in the clinical application of their recommendations. Moreover, while today's highly accurate carotid duplex scanning can obviate the need for preoperative angiography in many cases, the duplex criteria must be tailored to achieve sufficiently reliable results on which therapeutic decisions can be made. This review offers a clarification of the discrepancies between the angiographic grading techniques and how their measurements of percent stenosis correlate to the duplex criteria needed to support the treatment decision-making process for carotid obliterative disease.
authors.affiliation: Irvine Laboratory for Cardiovascular Investigation and Research, Imperial College of Science, Technology & Medicine, London, United Kingdom.
authors.forename: A N
authors.initials: AN
authors.lastname: Nicolaides
authors.forename: E G
authors.initials: EG
authors.lastname: Shifrin
authors.forename: A
authors.initials: A
authors.lastname: Bradbury
authors.forename: S
authors.initials: S
authors.lastname: Dhanjil
authors.forename: M
authors.initials: M
authors.lastname: Griffin
authors.forename: G
authors.initials: G
authors.lastname: Belcaro
authors.forename: M
authors.initials: M
authors.lastname: Williams
mesh_terms: D000792:Angiography / Q000379:methods / Q000592:standards*; D001783:Blood Flow Velocity; D002343:Carotid Artery, Internal; D016893:Carotid Stenosis / Q000145:classification* / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D002561:Cerebrovascular Disorders / Q000209:etiology; D006801:Humans; D018579:Patient Selection; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D018616:Ultrasonography, Doppler, Duplex / Q000592:standards*