title: Safety and feasibility of continuous monitoring of coronary flow velocity in acute myocardial infarction by Doppler guide wire.
abstract: We investigated the safety and limitations of the Doppler guide wire for continuous monitoring of coronary flow velocity outside the catheterization laboratory in 17 patients with acute myocardial infarction. After direct angioplasty, patients were taken to the coronary care unit with the Doppler guide wire positioned within the artery. Flow velocity was continuously monitored. Heparin was titrated to an active clotting time > 200 seconds. Clinical outcome and angiographic analyses were evaluated. Flow velocity monitoring was conducted with an 88.2% success rate and lasted for 16 +/- 5 hours. Monitoring failed in 2 of the 4 right coronary artery cases. Small amounts of thrombus were seen to adhere to the Doppler guide wire at the end of monitoring. No complications were related to the procedure. No deterioration of angiographic findings was observed. This preliminary study confirmed the safety of the Doppler guide wire for continuous monitoring of coronary flow in patients with acute myocardial infarction.
authors.affiliation: Third Department of Internal Medicine, Ohashi Hospital, Toho University School of Medicine. Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Nakamura
authors.forename: T
authors.initials: T
authors.lastname: Tsunoda
authors.forename: T
authors.initials: T
authors.lastname: Wakatsuki
authors.forename: K
authors.initials: K
authors.lastname: Ui
authors.forename: T
authors.initials: T
authors.lastname: Degawa
authors.forename: S
authors.initials: S
authors.lastname: Yabuki
authors.forename: T
authors.initials: T
authors.lastname: Yamaguchi
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D000925:Anticoagulants / Q000008:administration & dosage / Q000627:therapeutic use; D001777:Blood Coagulation / Q000187:drug effects; D001783:Blood Flow Velocity; D006328:Cardiac Catheterization; D017023:Coronary Angiography; D003326:Coronary Circulation; D003331:Coronary Vessels; D004867:Equipment Design; D004868:Equipment Failure; D005240:Feasibility Studies; D005260:Female; D006493:Heparin / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008297:Male; D018670:Monitoring, Ambulatory / Q000295:instrumentation; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000503:physiopathology*; D017063:Outcome Assessment, Health Care; D012449:Safety; D013927:Thrombosis / Q000209:etiology; D013997:Time Factors; D014463:Ultrasonography
chemical_list: D000925:Anticoagulants; D006493:Heparin