title: Computed tomographic assessment of noninvasive intranasal infusions in dogs with fungal rhinitis.
abstract: The distribution of infusate administered to 12 dogs with fungal rhinitis, using a noninvasive, intranasal technique, was evaluated by computed tomography (CT). In every dog, contrast medium was identified on the postinfusion CT images, within the frontal sinuses, and throughout all areas of the nasal cavity. Adverse effects were transient and mild. The results of this study indicate that intranasal infusion may be a viable alternative to trephination of the frontal sinuses to administer antifungal medications in dogs with fungal rhinitis.
authors.affiliation: Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis 95616, USA.
authors.forename: K G
authors.initials: KG
authors.lastname: Mathews
authors.forename: P D
authors.initials: PD
authors.lastname: Koblik
authors.forename: E F
authors.initials: EF
authors.lastname: Richardson
authors.forename: A P
authors.initials: AP
authors.lastname: Davidson
authors.forename: D
authors.initials: D
authors.lastname: Pappagianis
mesh_terms: D000281:Administration, Intranasal; D000818:Animals; D000935:Antifungal Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001228:Aspergillosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000662:veterinary; D002404:Catheterization / Q000662:veterinary; D003022:Clotrimazole / Q000008:administration & dosage / Q000627:therapeutic use; D003287:Contrast Media; D003453:Cryptococcosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000662:veterinary; D004283:Dog Diseases / Q000000981:diagnostic imaging* / Q000188:drug therapy; D004285:Dogs; D005626:Frontal Sinus / Q000000981:diagnostic imaging / Q000473:pathology; D007442:Intubation, Intratracheal / Q000662:veterinary; D017964:Itraconazole / Q000008:administration & dosage / Q000627:therapeutic use; D009181:Mycoses / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000662:veterinary*; D009296:Nasal Cavity / Q000000981:diagnostic imaging* / Q000473:pathology; D012220:Rhinitis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000662:veterinary*; D014057:Tomography, X-Ray Computed / Q000379:methods / Q000662:veterinary
chemical_list: D000935:Antifungal Agents; D003287:Contrast Media; D017964:Itraconazole; D003022:Clotrimazole