[Density of lymphocyte beta-2 adrenoreceptors in the course of hypertension].
Baseline density of intact lymphocyte beta2 adrenoreceptors (B max., 3H-DHA) was compared to dynamics of left ventricular hypertrophy (LVH) and frequency of essential hypertension (EH) complications within 7-9-year follow-up in 27 patients with EH stage II. No significant correlation was noted between B max and LVH changes. In a subgroup of 9 patients with initially very high B max overall number of complications reached 77.8% against 27.5%) (p<0.05) in control. These patients also developed acute myocardial infarctions more frequently (33.3% versus 0%, p<0.05). Such complications as strokes, coronary failure occurred with the same frequency. More extended trials are needed to infer on prognostic value of lymphocytic beta2-adrenoreceptor density.
Parfenova
E I
EI
Krasnikova
T L
TL
D'iakonova
E G
EG
Masenko
V P
VP
Shinbaeva
N A
NA
Kivaeva
G M
GM
Mazaev
A V
AV
D000328:Adult; D002499:Centrifugation, Density Gradient; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000503:physiopathology*; D017379:Hypertrophy, Left Ventricular / Q000503:physiopathology; D008214:Lymphocytes / Q000737:chemistry*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D018343:Receptors, Adrenergic, beta-2 / Q000032:analysis* / Q000502:physiology; D013997:Time Factors
D018343:Receptors, Adrenergic, beta-2