[Serum neopterin in Behçet's disease].
Neopterin radioimmunoassay measurements (Henning, Berlin) were conducted in 26 male and 12 female patients (mean age 32 +/- 8.01) with Behcet's disease (BD) and healthy controls. In BD patients mean serum neopterin concentrations were significantly higher than in the controls (8.7 +/- 4.1 nmol/l against 5.0 +/- 1.9 nmol/l, respectively). Neopterin levels were higher in patients with positive pathergy test than in negative subjects (p<0.05). There was a significant correlation between neopterin and CRP (rs=0.42. p<0.02). The findings indicate that cellular immunity in BD patients is activated.
Samsonov
M Iu
MIu
Prokaeva
T B
TB
Madanat
V
V
Alekberova
Z S
ZS
Nasonov
E L
EL
Fuks
D
D
Vakhter
Kh
Kh
D000328:Adult; D001528:Behcet Syndrome / Q000097:blood*; D001708:Biopterins / Q000031:analogs & derivatives* / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D019798:Neopterin; D011863:Radioimmunoassay
D001708:Biopterins; D019798:Neopterin; D002097:C-Reactive Protein