title: Resolution of hyperthyroidism in a pregnant woman with toxic thyroid nodule by percutaneous ethanol injection.
abstract: Overt hyperthyroidism was found in a 35-year-old pregnant woman at the 13th week of gestation who was referred to us for tachycardia, tremors, and weight loss. Clinical signs, symptoms, and laboratory findings led to the diagnosis of toxic thyroid nodule. She was treated with ultrasound guided percutaneous ethanol injection (PEI) and, after 2 weeks of treatment, the woman was completely euthyroid. These findings suggest that during pregnancy PEI appears to be a rapid and safe therapy for toxic nodular goiter and an effective alternative to the administration of antithyroid drugs.
authors.affiliation: Institute of Endocrine Sciences, Ospedale Maggiore IRCCS, Milano, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Cortelazzi
authors.forename: D
authors.initials: D
authors.lastname: Castagnone
authors.forename: B
authors.initials: B
authors.lastname: Tassis
authors.forename: E
authors.initials: E
authors.lastname: Venegoni
authors.forename: R
authors.initials: R
authors.lastname: Rivolta
authors.forename: P
authors.initials: P
authors.lastname: Beck-Peccoz
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000431:Ethanol / Q000008:administration & dosage; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood / Q000473:pathology / Q000628:therapy*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000473:pathology / Q000628:therapy*; D013963:Thyroid Hormones / Q000097:blood; D016606:Thyroid Nodule / Q000097:blood / Q000628:therapy* / Q000648:ultrastructure; D013972:Thyrotropin / Q000097:blood
chemical_list: D013963:Thyroid Hormones; D000431:Ethanol; D013972:Thyrotropin