DNA ploidy and cell cycle analysis in cancer diagnosis and prognosis.
This review focuses on the clinical utility and potential value of cell cycle analysis and DNA ploidy interpretation in the diagnosis of human tumors, the application of these techniques to cytologic diagnosis, and their capability for predicting disease outcome in human neoplasia. Methods of cell cycle analysis are considered, and the techniques of flow cytometry and image analysis are described.
Ross
J S
JS
Department of Pathology and Laboratory Medicine, Albany Medical College, New York, USA.
D002453:Cell Cycle / Q000235:genetics; D002455:Cell Division / Q000235:genetics; D004273:DNA, Neoplasm / Q000032:analysis*; D005434:Flow Cytometry / Q000379:methods; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D009369:Neoplasms / Q000175:diagnosis* / Q000235:genetics*; D011003:Ploidies; D011379:Prognosis
D004273:DNA, Neoplasm