Modulation of growth of human gastric enterochromaffin-like cells.
We consider the multiple interacting factors which lead to the proliferation of human gastric enterochromaffin-like (ECL) cells, and control of this proliferation by somatostatin and its analogues. Somatostatin receptors occur in human fundic mucosa, and octreotide can be considered a useful therapeutic tool to control gastrin-driven ECL cell growth in humans.
Delle Fave
G
G
Cattedra di Gastroenterologia, Università La Sapienza Roma, Italia.
Annibale
B
B
D000818:Animals; D002455:Cell Division / Q000502:physiology; D004759:Enterochromaffin Cells / Q000502:physiology*; D006801:Humans; D013270:Stomach / Q000166:cytology*