title: A nine-year follow up study of a population occupationally exposed to vinyl chloride monomer.
abstract: The presence of structural chromosome aberrations and sister chromatid exchange frequencies (SCE) were studied in lymphocytes from 28 male subjects occupationally exposed to vinyl chloride monomer for a period of 9 years. A significant increase in chromosomal damages and elevated SCE frequencies was detected during the third and fourth year of the follow-up study. During the last 2 years, all examined parameters are approaching control values. This is a result of decreasing vinyl chloride monomer concentrations in the working environment without interrupting the working process.
authors.affiliation: Institute for Medical Research and Occupational Health, Zagreb, Croatia.
authors.forename: A
authors.initials: A
authors.lastname: Fucić
authors.forename: D
authors.initials: D
authors.lastname: Barković
authors.forename: V
authors.initials: V
authors.lastname: Garaj-Vrhovac
authors.forename: D
authors.initials: D
authors.lastname: Kubelka
authors.forename: B
authors.initials: B
authors.lastname: Ivanic
authors.forename: T
authors.initials: T
authors.lastname: Dabo
authors.forename: A
authors.initials: A
authors.lastname: Mijić
mesh_terms: D000328:Adult; D000368:Aged; D002869:Chromosome Aberrations; D004249:DNA Damage; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced*; D012854:Sister Chromatid Exchange; D013997:Time Factors; D014752:Vinyl Chloride / Q000633:toxicity*
chemical_list: D014752:Vinyl Chloride