Canine idiopathic thrombocytopenic purpura.
Canine idiopathic thrombocytopenic purpura (ITP) is a disease in which antibodies bound to the surface of platelets mediate premature platelet destruction by macrophages. ITP in dogs and chronic ITP in humans are analogous diseases. This article draws on information from the literature on ITP in dogs and in humans, and reviews the pathogenesis, diagnosis, and treatment of ITP in dogs.
Lewis
D C
DC
Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan 66506-5606, USA.
Meyers
K M
KM
D000818:Animals; D001792:Blood Platelets / Q000502:physiology; D004283:Dog Diseases; D004285:Dogs; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D017713:Platelet Transfusion; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy / Q000662:veterinary*; D012727:Sex Characteristics; D013156:Splenectomy; D014750:Vincristine / Q000627:therapeutic use
D005938:Glucocorticoids; D016756:Immunoglobulins, Intravenous; D007166:Immunosuppressive Agents; D014750:Vincristine