MURCS association: case report and review.
We report on a 25 year old woman with aplasia of the Müllerian duct, unilateral renal agenesis, and anomalies of the cervicothoracic somites (MURCS association). Growth retardation and facial asymmetry were also present. A review of published reports allows MURCS association to be distinguished from related associations, sequences, and syndromes. Moreover, sporadic occurrence, the broad spectrum of associated anomalies, and the involvement of different organ systems closely related in early embryogenesis are arguments for considering MURCS association as the consequence of a developmental field defect.
Braun-Quentin
C
C
Institute of Human Genetics, University of Erlangen-Nürnberg, Germany.
Billes
C
C
Böwing
B
B
Kotzot
D
D
D000328:Adult; D005314:Embryonic and Fetal Development; D005260:Female; D006801:Humans; D007668:Kidney / Q000002:abnormalities; D009095:Mullerian Ducts / Q000002:abnormalities*; D011859:Radiography; D019170:Somites / Q000378:metabolism*