title: Obstructive jaundice caused by non-parasitic hepatic cyst treated with percutaneous drainage and instillation of minocycline hydrochloride as a sclerosing agent.
abstract: We report a case of obstructive jaundice caused by a large hepatic cyst which was successfully treated by percutaneous drainage and instillation of minocycline hydrochloride. An 88-year-old man presented with obstructive jaundice and upper abdominal fullness. Abdominal CT and ultrasonography revealed a large hepatic cyst and intrahepatic bile duct dilatation. After the percutaneous drainage of the cyst, minocycline hydrochloride was instilled as a sclerosant via a catheter into the cyst cavity. Liver enzyme levels returned to normal and the jaundice disappeared. Nine months after the treatment, the large cyst and dilatation of the intrahepatic bile duct had disappeared. The patient has remained healthy without symptoms.
authors.affiliation: Department of General Medicine, Saga Medical School.
authors.forename: K
authors.initials: K
authors.lastname: Yoshihara
authors.forename: S
authors.initials: S
authors.lastname: Yamashiro
authors.forename: S
authors.initials: S
authors.lastname: Koizumi
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuo
authors.forename: J
authors.initials: J
authors.lastname: Shigeru
authors.forename: S
authors.initials: S
authors.lastname: Kanegae
authors.forename: Y
authors.initials: Y
authors.lastname: Oda
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002780:Cholestasis, Intrahepatic / Q000209:etiology*; D003560:Cysts / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy; D004322:Drainage / Q000295:instrumentation; D006801:Humans; D007322:Instillation, Drug; D008107:Liver Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy; D008297:Male; D008911:Minocycline / Q000008:administration & dosage / Q000627:therapeutic use*; D012597:Sclerosing Solutions / Q000008:administration & dosage / Q000627:therapeutic use*; D015911:Sclerotherapy; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D012597:Sclerosing Solutions; D008911:Minocycline