Gastroschisis: are prenatal ultrasonographic findings useful for assessing the prognosis?
OBJECTIVE
The objective of this study was to assess various prenatal patterns in correlation with survival and the occurrence of complications of antenatally recognized gastroschisis (G).


METHODS
We retrospectively studied 34 cases of G. Mortality and morbidity in the postnatal period were assessed and correlated with the prenatal presence or absence of: (1) bowel and/or stomach dilatation, (2) thickening and/or hyperechogenicity of the intestinal wall, (3) meconium peritonitis (in the abdomen) before 20 weeks of gestation, (4) asymmetrical bowel dilatation, and (5) associated malformations. Morbidity took into account the length of hospitalization and the number of surgical procedures.


RESULTS
The overall survival rate was 94%. Neither bowel nor stomach dilatation was significantly correlated with mortality. However, evidence of intestinal dilatation greater than 17 mm had a positive predictive value of 67% for atresia, with a negative predictive value of 86%. Thickening and/or hyperechogenicity of the bowel wall were not significantly associated with mortality. Meconium peritonitis before 20 weeks and asymmetrical bowel dilatation were not statistically significant because of the small sample size. Twelve patients (35.3%) had postnatal complications, with a mean hospital stay of 127 days. Outcome was not modified by the mode of delivery. Associated extradigestive anomalies were present in 20.6% of cases. Chromosomal anomalies were not seen.


CONCLUSIONS
The prognosis of prenatally detected G is excellent despite the frequency of small bowel atresia (67%) in the group with postnatal complications. Meconium peritonitis before 20 weeks of gestation and/ or asymmetrical bowel dilatation also appear to be indicators of atresia (2/4, 50%) or high morbidity (3/4, 75%).
Brun
M
M
Department of Radiology, Hôpital Sainte-Justine, Côte-Ste-Catherine, Montreal, Quebec, Canada.
Grignon
A
A
Guibaud
L
L
Garel
L
L
Saint-Vil
D
D
D000009:Abdominal Muscles / Q000002:abnormalities* / Q000000981:diagnostic imaging; D000015:Abnormalities, Multiple; D000328:Adult; D000013:Congenital Abnormalities / Q000401:mortality; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007422:Intestines / Q000002:abnormalities / Q000000981:diagnostic imaging; D008297:Male; D011237:Predictive Value of Tests; D011247:Pregnancy; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate; D016216:Ultrasonography, Prenatal