A novel representation of protein structure.
Using a nonlinear mapping technique, we demonstrate that proteins folded in two dimensions display the same overall structural features as their three-dimensional counterparts. The two-dimensional representation of protein structure provides a novel way to visualize structural as well as distance information. It may also provide a link for deriving three-dimensional structure from amino acid sequence.
Barlow
T W
TW
Physical Chemistry Laboratory, Oxford, England.
Richards
W G
WG
D003196:Computer Graphics; D003198:Computer Simulation; D008958:Models, Molecular; D017510:Protein Folding; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry*
D011506:Proteins