title: Valacyclovir HCl (Valtrex): an acyclovir prodrug with improved pharmacokinetics and better efficacy for treatment of zoster.
authors.affiliation: Glaxo Wellcome Inc., Research Triangle Park, North Carolina, USA.
authors.forename: M L
authors.initials: ML
authors.lastname: Smiley
authors.forename: A
authors.initials: A
authors.lastname: Murray
authors.forename: P
authors.initials: P
authors.lastname: de Miranda
mesh_terms: D000212:Acyclovir / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000493:pharmacokinetics / Q000627:therapeutic use; D000818:Animals; D000998:Antiviral Agents / Q000009:adverse effects / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D006562:Herpes Zoster / Q000188:drug therapy* / Q000821:virology; D006566:Herpesviridae Infections / Q000188:drug therapy / Q000821:virology; D006801:Humans; D011355:Prodrugs / Q000009:adverse effects / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D000077483:Valacyclovir; D014633:Valine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000493:pharmacokinetics / Q000627:therapeutic use
chemical_list: D000998:Antiviral Agents; D011355:Prodrugs; D014633:Valine; D000077483:Valacyclovir; D000212:Acyclovir