title: Findlay implantable two-stage centrifugal pump.
abstract: The Findlay centrifugal pump is unique in its two-stage pumping mechanisms and in its complementary interrelationship of the stages to each other and to the exit system, and it forms an extremely efficient unit. The first stage is a lift force pump as an inlet. The second and major stage is a shear force pump. Twenty-six prototypes, many multiply modified, have been hand fabricated, and most have had classic pump function analyses. Six pumps have demonstrated minimal hemolysis (3.5-5 h). At modest rotation speeds, it pumps water up to 10 L/min. Forty-four acute studies in normal dogs have been performed with the Findlay pump in a ventricular assist system. Blood flows through the pump ranged from 1.2 to 4.5 L/min. The conclusion is that the Findlay pump has the ability to operate with low blood damage, performs at acceptable rotational speed with reasonable hydraulic and mechanical efficiency, and is small and implantable.
authors.affiliation: Louisiana State University, New Orleans, USA.
authors.forename: P V
authors.initials: PV
authors.lastname: Moulder
authors.forename: I S
authors.initials: IS
authors.lastname: Findlay
authors.forename: R M
authors.initials: RM
authors.lastname: Zone
authors.forename: A J
authors.initials: AJ
authors.lastname: Thompson
authors.forename: H A
authors.initials: HA
authors.lastname: Silber
authors.forename: W R
authors.initials: WR
authors.lastname: Rank
authors.forename: M D
authors.initials: MD
authors.lastname: Charbonnet
authors.forename: W R
authors.initials: WR
authors.lastname: Webb
authors.forename: L H
authors.initials: LH
authors.lastname: Harrison
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001783:Blood Flow Velocity / Q000502:physiology; D002302:Cardiac Output / Q000502:physiology; D002498:Centrifugation; D004285:Dogs; D006353:Heart-Assist Devices / Q000009:adverse effects / Q000592:standards / Q000639:trends; D006439:Hemodynamics / Q000502:physiology; D006461:Hemolysis; D066298:In Vitro Techniques; D008962:Models, Theoretical; D011183:Postoperative Complications; D011312:Pressure
chemical_list: D001672:Biocompatible Materials