title: Younger age as a bad prognostic factor in patients with carcinoma of the cervix.
abstract: OBJECTIVE
  To verify the influence of age on the prognosis of cervix carcinoma.
  
  
  METHODS
  Five hundred and sixty eight patients treated for a FIGO stage IB-IVA with radical irradiation in the Centre Hospitalier Universitaire Vaudois of Lausanne were subdivided according to the following age categories: < or = 45, 46-60, 61-69 and >70 years. Taking the 46-60 years age group as the reference, the hazard ratios (HR) of death and corresponding 95% confidence intervals (95% CI) were estimated by means of a Cox multivariate analysis.
  
  
  RESULTS
  The 5-year survival rates were, respectively, 57%, 67%, 60% and 45%. For the youngest women the risk of death was significantly increased (HR = 2.00, 95% CI [1.32-3.00]) and was even more accentuated in advanced stages.
  
  
  CONCLUSIONS
  Age under 45 years is a bad prognostic factor in carcinoma of the cervix.
authors.affiliation: Departement de Gynecologie et d'Obstetrique, Centre Hospitalier Universitaire, Vaudois, Switzerland.
authors.forename: J F
authors.initials: JF
authors.lastname: Delaloye
authors.forename: S
authors.initials: S
authors.lastname: Pampallona
authors.forename: P A
authors.initials: PA
authors.lastname: Coucke
authors.forename: P
authors.initials: P
authors.lastname: De Grandi
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002277:Carcinoma / Q000401:mortality* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000401:mortality* / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery