title: Locally derived clinical practice guidelines using a decision analysis model.
abstract: As health-care providers continually are faced with the need to identify the most cost-effective modalities when initiating therapy among many therapeutic options, standardized clinical guidelines become the foundation for decision making. This article discusses how decision analysis can be useful in the formulation of locally derived clinical practice guidelines. The following is an example of using decision analysis to evaluate data gathered within the institution, supplemented by peer-reviewed literature, to choose the most cost-effective agent in the treatment of chemotherapy-induced nausea and vomiting at the authors' institution.
authors.forename: A H
authors.initials: AH
authors.lastname: Mutnick
authors.forename: B A
authors.initials: BA
authors.lastname: Szymusiak-Mutnick
mesh_terms: D000932:Antiemetics / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects; D003362:Cost-Benefit Analysis; D003663:Decision Trees; D006801:Humans; D009325:Nausea / Q000139:chemically induced / Q000188:drug therapy*; D018024:Peer Review, Health Care; D017410:Practice Guidelines as Topic; D014839:Vomiting / Q000139:chemically induced / Q000188:drug therapy*
chemical_list: D000932:Antiemetics; D000970:Antineoplastic Agents