title: An EcoRI RFLP in human APC gene.
abstract: A novel EcoRI-restriction fragment length polymorphism in the genomic sequence of the human adenomatous polyposis coli (APC) gene is described. This polymorphism in the APC gene would be very useful for examination of segregation of the mutated APC gene in the kindreds of familial adenomatous polyposis, and also for studying the loss of heterozygosity at the APC region in certain tumors.
authors.affiliation: Department of Medical Genetics, Osaka University Medical School, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kurahashi
authors.forename: K
authors.initials: K
authors.lastname: Takami
authors.forename: I
authors.initials: I
authors.lastname: Yana
authors.forename: K
authors.initials: K
authors.lastname: Akagi
authors.forename: S
authors.initials: S
authors.lastname: Okada
authors.forename: I
authors.initials: I
authors.lastname: Nishisho
mesh_terms: D015246:Deoxyribonuclease EcoRI; D017491:Genes, APC / Q000235:genetics*; D006801:Humans; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D015246:Deoxyribonuclease EcoRI