title: Lysis of intravascular thrombus prior to coronary stenting using the dispatch infusion catheter.
abstract: The presence of angiographic evidence of thrombus is generally thought to be a contraindication to coronary stent placement. This report describes four patients in whom angiographic thrombus was lysed using the Dispatch infusion catheter prior to coronary stenting. Urokinase was infused via the Dispatch catheter with resolution of angiographic evidence of thrombus in all cases. No complications were encountered using this technique, and all patients had excellent angiographic results after stenting. We conclude that lysis of intracoronary thrombus using the Dispatch infusion catheter is feasible and appears safe in this small study. Further trials are needed to determine if this technique reduces the acute stent thrombosis rate compared to other techniques for stent deployment in the presence of angiographic evidence of thrombus.
authors.affiliation: Section of Cardiology, University of Florida, Shands Hospital, Gainesville 32610-0277, USA.
authors.forename: R A
authors.initials: RA
authors.lastname: Kerensky
authors.forename: E A
authors.initials: EA
authors.lastname: Franco
authors.forename: B D
authors.initials: BD
authors.lastname: Bertolet
authors.forename: G
authors.initials: G
authors.lastname: Thomas
authors.forename: T J
authors.initials: TJ
authors.lastname: Wargovich
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D017023:Coronary Angiography; D003328:Coronary Thrombosis / Q000000981:diagnostic imaging / Q000628:therapy*; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D007261:Infusions, Intra-Arterial; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011292:Premedication; D015607:Stents; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage*
chemical_list: D006493:Heparin; D014568:Urokinase-Type Plasminogen Activator