title: Role of Doppler ultrasonography in the prediction of pregnancy outcome in women with recurrent spontaneous abortion.
abstract: We prospectively studied 96 patients with a history of recurrent spontaneous abortion to determine whether the resistive index of the main uterine artery or subchorionic vessels can allow prediction of pregnancy outcome. The subchorionic RI declined progressively for a mean of 0.54 at 6 weeks to 0.42 at 13 weeks (P < 10(-8), F-test). No significant difference was found in subchorionic RI values between outcomes for liveborn infants versus loss. Uterine artery RI values also declined significantly through the first trimester (P < 10(-8), F-test). Uterine artery RI values tended to be lower in pregnancies ending in loss than in successful gestations; however, there was too much overlap for this index to be clinically useful. In conclusion, first trimester RI does not allow prediction of pregnancy outcome in patients with recurrent abortion.
authors.affiliation: Department of Radiology, Brigham & Women's Hospital, Boston, MA 02115, USA.
authors.forename: M C
authors.initials: MC
authors.lastname: Frates
authors.forename: P M
authors.initials: PM
authors.lastname: Doubilet
authors.forename: D L
authors.initials: DL
authors.lastname: Brown
authors.forename: C B
authors.initials: CB
authors.lastname: Benson
authors.forename: D N
authors.initials: DN
authors.lastname: DiSalvo
authors.forename: F C
authors.initials: FC
authors.lastname: Laing
authors.forename: D J
authors.initials: DJ
authors.lastname: Berck
authors.forename: J A
authors.initials: JA
authors.lastname: Hill
mesh_terms: D000026:Abortion, Habitual / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000517:prevention & control; D000328:Adult; D001783:Blood Flow Velocity; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008875:Middle Aged; D021041:Placental Circulation; D011237:Predictive Value of Tests; D011247:Pregnancy; D011256:Pregnancy Outcome; D011374:Progesterone / Q000627:therapeutic use; D011446:Prospective Studies; D012008:Recurrence; D018608:Ultrasonography, Doppler / Q000379:methods*; D016216:Ultrasonography, Prenatal
chemical_list: D011374:Progesterone