title: Three-dimensional model of a hairpin ribozyme.
abstract: On the basis of the mutational and chemical-modification analysis, we propose the new secondary structure of a hairpin ribozyme, which contains three stems, a triple helix and the reverse Watson-Crick g+1C44 base pair at the 3' side of the cleavage site. The computational approach to the tertiary structure of a hairpin ribozyme have been carried out.
authors.affiliation: Institute for Protein Research, Osaka University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Amano
authors.forename: S
authors.initials: S
authors.lastname: Fujii
mesh_terms: D001482:Base Composition; D001483:Base Sequence; D001665:Binding Sites; D008274:Magnesium / Q000378:metabolism; D008958:Models, Molecular; D008969:Molecular Sequence Data; D015394:Molecular Structure; D017860:Nepovirus / Q000201:enzymology / Q000235:genetics; D009690:Nucleic Acid Conformation; D016337:RNA, Catalytic / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D019244:RNA, Satellite / Q000737:chemistry / Q000235:genetics / Q000378:metabolism
chemical_list: D016337:RNA, Catalytic; D019244:RNA, Satellite; D008274:Magnesium