Quantitative EEG in frontal lobe dementia.
A study on quantitative EEG in 14 patients with frontal lobe dementia (FLD), 14 patients with Alzheimer's disease (AD), and 14 healthy controls was conducted using a complete set of EEG parameters: band power, coherence and fractal dimension. Contrary to earlier studies, we observed higher theta power and sagittal interactions in higher frequency bands in the FLD than in the control group. Lateral interactions of coherence and two indices of fractal dimension were lower in FLD than in controls. There was greater electrophysiological resemblance between the control group and FLD than between any of these groups and AD. This was documented by the results of a discriminant analysis which led to a correct overall classification of 66% of the subjects with misclassifications occurring primarily between control and FLD group.
Besthorn
C
C
Central Institute of Mental Health, Mannheim, Federal Republic of Germany.
Sattel
H
H
Hentschel
F
F
Daniel
S
S
Zerfass
R
R
Förstl
H
H
D000704:Analysis of Variance; D003704:Dementia / Q000503:physiopathology*; D004569:Electroencephalography; D005625:Frontal Lobe / Q000503:physiopathology*; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008875:Middle Aged