[Level of neuropeptide Y in serum of patients with chronic congestive heart failure].
The purpose of the study was to measure plasma concentrations of neuropeptide Y (NPY), endothelin-1,2 (ET-1,2), alpha atrial natriuretic polypeptide (ANP) and noradrenaline (NA) in relation to cardiac index (CI) and left ventricular ejection fraction (LVEF) in patients with congestive heart failure (CHF). There were significant increases in venous blood concentrations of NPY, Na, ET-1,2, ANP in the patients with CHF. Plasma concentrations of NPY correlated with plasma NA concentrations but plasma noradrenaline concentrations alone correlated with CI and LVEF. In patients with CHF plasma NA concentrations seems to be more sensitive index of cardiac dysfunction then the concentrations of neuropeptide Y.
Halawa
B
B
Katedry i Kliniki Kardiologii AM we Wrocławiu.
D009320:Atrial Natriuretic Factor / Q000097:blood; D016232:Endothelins / Q000097:blood; D006333:Heart Failure / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009478:Neuropeptide Y / Q000097:blood*; D009638:Norepinephrine / Q000097:blood; D013318:Stroke Volume
D016232:Endothelins; D009478:Neuropeptide Y; D009320:Atrial Natriuretic Factor; D009638:Norepinephrine