title: Pre-term delivery and subsequent ocular development. A 7-10 year follow-up of children screened 1982-84 for ROP. 1) Visual function, slit-lamp findings, and fundus appearance.
abstract: An ophthalmic follow-up comprised 88 children aged 7-10 years who had regular screening for retinopathy of prematurity (ROP) after their pre-term delivery 1982-84. Mean values of birth weight and gestational age in the 88 were 1467 g and 31 weeks. Out of 28 with early evidence of ROP four had progressed to bilateral blindness; the remaining 24 had at least a corrected visual acuity of 0.4 at disposal. The corrected median binocular acuity for all 88 was 0.95; however, the cumulated frequency curve was significantly below a previously stated norm in full-terms. The same conclusion was valid for single eye vision. Within the material, the visual score of the 28 with early ROP was significantly lower than in the remaining 60 subjects. Ophthalmoscopy often showed tortuosity of vessels, but no specific central retinal or optic nerve lesion to explain the slight general depression of visual acuity, and opacities of media contributed in only two subjects. It is concluded, that very preterm delivery generally influences the potential for developing full visual acuity, also in individuals without evidence of early ROP. Evidence of CNS-damage negatively influenced visual acuity score.
authors.affiliation: Eye Department, Hillerød Sygehus and Rigshospitalet, Copenhagen University, Denmark.
authors.forename: H C
authors.initials: HC
authors.lastname: Fledelius
mesh_terms: D000065:Accommodation, Ocular / Q000502:physiology; D002648:Child; D003118:Color Perception / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D005654:Fundus Oculi; D005865:Gestational Age; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008297:Male; D007752:Obstetric Labor, Premature; D009799:Ocular Physiological Phenomena; D009887:Ophthalmoscopy; D011247:Pregnancy; D012178:Retinopathy of Prematurity / Q000175:diagnosis / Q000503:physiopathology*; D014792:Visual Acuity / Q000502:physiology*; D014794:Visual Fields / Q000502:physiology*