title: [Colitis induced by a food allergen. A report of 20 cases].
abstract: In the last years, we have appreciated a descending number of classic enteral food-protein intolerance and cases of colitis related to food proteins are increasing. In this study, 20 cases of food protein colitis (mainly related to cow's milk) are reviewed and clinical, endoscopic and histological aspects are analyzed. We found that the age at the time of the first consultation was approximately 1.5 months, with males predominating. The main symptom was bloody diarrhoea. Other causes such as perianal fissure or infectious gastroenteritis were excluded. The infants were fed breast milk and/or cow's milk formula. Some patients had low hemoglobin, but low serum albumin was infrequent. The colonoscopy showed erythema and, in some cases, loss of vascular pattern, ulcerations or bleeding. The main histological finding was an increased number of eosinophils. There was a favorable response to the dietary change. After 6 months, all of the provocations done were negative. We conclude that food-protein intolerance is one of the most probable causes of bloody stools in a young infant. Colonoscopy and a histopathological study of at least three biopsy pieces are necessary for the diagnosis. The treatment is the exclusion of the offending protein from the diet.
authors.affiliation: Servicio de Gastroenterología y Nutrición Pediátricas, Hospital Infantil La Paz, Madrid.
authors.forename: A
authors.initials: A
authors.lastname: Armisén Pedrejón
authors.forename: B
authors.initials: B
authors.lastname: Sancho Madrid
authors.forename: E
authors.initials: E
authors.lastname: Almaraz Garzón
authors.forename: G
authors.initials: G
authors.lastname: Prieto Bozano
authors.forename: I
authors.initials: I
authors.lastname: Polanco Allué
mesh_terms: D000485:Allergens / Q000009:adverse effects*; D001706:Biopsy; D003092:Colitis / Q000175:diagnosis / Q000209:etiology*; D003106:Colon / Q000473:pathology; D003113:Colonoscopy; D003937:Diagnosis, Differential; D004044:Dietary Proteins / Q000009:adverse effects*; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D016269:Milk Hypersensitivity / Q000175:diagnosis; D012189:Retrospective Studies
chemical_list: D000485:Allergens; D004044:Dietary Proteins