title: Is renal dose dopamine protective or therapeutic? No.
abstract: This article argues that dopamine infused in low doses has not been shown to avert the onset of or ameliorate the course of acute renal failure in critically ill patients. The inotropic and diuretic effects of dopamine are discussed, and its adverse effects are described. An attempt is made to offer an evidence-based role for low-dose dopamine, namely as a diuretic in ventilated, euvolemic patients, resistant to conventional diuretic therapy.
authors.affiliation: Department of Anaesthesia and Intensive Care, Faculty of Medicine and Health Sciences, University of Newcastle, Callaghan, Australia.
authors.forename: D B
authors.initials: DB
authors.lastname: Cottee
authors.forename: W P
authors.initials: WP
authors.lastname: Saul
mesh_terms: D058186:Acute Kidney Injury / Q000188:drug therapy* / Q000503:physiopathology; D003422:Critical Care; D016638:Critical Illness; D004298:Dopamine / Q000494:pharmacology / Q000627:therapeutic use*; D004351:Drug Resistance; D019317:Evidence-Based Medicine; D006801:Humans; D012121:Respiration, Artificial; D016896:Treatment Outcome
chemical_list: D004298:Dopamine