Measles immunization in children with a history of egg allergy.
This study investigated the use of measles vaccine in children with a history of egg protein hypersensitivity, referred between 1987 and 1993 to a specialist immunization facility. Two hundred children were seen of whom 199 were immunized without any adverse effect; one child had an anaphylactic reaction. The proportion experiencing an anaphylactic reaction was 0.5% (95% CI 0.01-2.75%). It is believed that a history of egg protein allergy should no longer be regarded as a contra-indication to vaccination. Skin testing prior to measles immunization should, however, continue.
Baxter
D N
DN
Stepping Hill Hospital, Stockport, UK.
D000707:Anaphylaxis / Q000209:etiology; D002648:Child; D002675:Child, Preschool; D015387:Egg Proteins, Dietary / Q000009:adverse effects*; D005260:Female; D005512:Food Hypersensitivity / Q000276:immunology*; D006801:Humans; D008297:Male; D008457:Measles / Q000517:prevention & control; D008458:Measles Vaccine / Q000009:adverse effects* / Q000276:immunology*; D012882:Skin Tests
D015387:Egg Proteins, Dietary; D008458:Measles Vaccine