title: [The effect of calcium antagonists and the potassium depolarization of plasma membranes on pepsinogen extrusion by dispersed gastric glands].
abstract: The effect exerted by the calcium-free medium, calcium antagonists (La3+, Mn2+, nifedipin, nitrendipin, verapamil) and by potassium depolarization on the pepsinogen extrusion by the dispersed gastric glands of guinea pigs has been investigated. The obtained results prove the absence of potential-dependent Ca2+ transport into the gastric gland cells. Apparently Ca(2+)-transport into these cells is mediated by the chemosensitive Ca2+ channels.
authors.forename: L O
authors.initials: LO
authors.lastname: Dubyts'kyĭ
authors.forename: H I
authors.initials: HI
authors.lastname: Sabadash
mesh_terms: D000818:Animals; D002121:Calcium Channel Blockers / Q000494:pharmacology*; D015220:Calcium Channels / Q000187:drug effects / Q000502:physiology; D002462:Cell Membrane / Q000187:drug effects / Q000378:metabolism; D005753:Gastric Mucosa / Q000187:drug effects* / Q000378:metabolism; D006168:Guinea Pigs; D066298:In Vitro Techniques; D010435:Pepsinogens / Q000187:drug effects* / Q000378:metabolism; D011188:Potassium / Q000502:physiology*; D011189:Potassium Chloride / Q000494:pharmacology
chemical_list: D002121:Calcium Channel Blockers; D015220:Calcium Channels; D010435:Pepsinogens; D011189:Potassium Chloride; D011188:Potassium