Adult respiratory distress syndrome induced by a Chinese medicine, Kamisyoyo-san.
We report the first case of Kamisyoyo-san-induced adult respiratory distress syndrome (ARDS). A 59-year-old female was given Kamisyoyo-san for treatment of seborrheic dermatitis. She then presented with a respiratory illness having clinical, radiologic and functional characteristics of ARDS. Bronchoalveolar lavage fluid showed an increased number of lymphocytes, neutrophils and eosinophils. The lymphocyte stimulation test with Kamisyoyo-san was positive.
Shiota
Y
Y
Department of Clinical Research, Kure Kyosai Hospital.
Wilson
J G
JG
Matsumoto
H
H
Munemasa
M
M
Okamura
M
M
Hiyama
J
J
Marukawa
M
M
Ono
T
T
Taniyama
K
K
Mashiba
H
H
D029972:Bupleurum; D016516:CD4-CD8 Ratio; D012628:Dermatitis, Seborrheic / Q000188:drug therapy; D004365:Drugs, Chinese Herbal / Q000009:adverse effects* / Q000494:pharmacology; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000139:chemically induced; D008213:Lymphocyte Activation / Q000187:drug effects; D008875:Middle Aged; D010936:Plant Extracts / Q000009:adverse effects* / Q000494:pharmacology; D011654:Pulmonary Edema / Q000139:chemically induced; D011657:Pulmonary Eosinophilia / Q000139:chemically induced*; D012128:Respiratory Distress Syndrome / Q000139:chemically induced*
C051274:Bupleurum root extract; D004365:Drugs, Chinese Herbal; D010936:Plant Extracts; C103354:kamisyoyo san