title: Long-term follow-up of residual mediastinal masses in treated Hodgkin's disease using MR imaging.
abstract: OBJECTIVE
  Long-term follow-up of residual mediastinal masses in treated Hodgkin's disease using MR imaging.
  
  
  METHODS
  Ten patients, with substantial residual mediastinal masses of low signal intensity (SI) in the T2-weighted image (T2WI), were reinvestigated with MR 19-79 months after completing treatment of Hodgkin's disease. All patients were in complete remission.
  
  
  RESULTS
  During the follow-up period, the masses had decreased in size by 0-95% (median 67%) as compared to their initial post-therapy size. The SI continued to be low in the T2WI and was unaffected by the degree of size reduction.
  
  
  CONCLUSIONS
  It is speculated that these mainly fibrotic residual masses undergo slow degradation of the fibrotic part and/or resorption of remaining inflammatory tissue. It is important to understand the natural, long-term MR imaging changes of these residual masses in order more easily to recognize tumour recurrence or other pathologic conditions.
authors.affiliation: Department of Diagnostic Radiology, University Hospital of Uppsala, Sweden.
authors.forename: R
authors.initials: R
authors.lastname: Nyman
authors.forename: G
authors.initials: G
authors.lastname: Forsgren
authors.forename: B
authors.initials: B
authors.lastname: Glimelius
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006689:Hodgkin Disease / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008479:Mediastinal Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy; D018365:Neoplasm, Residual; D013997:Time Factors