title: A gene map of the human genome.
abstract: The human genome is thought to harbor 50,000 to 100,000 genes, of which about half have been sampled to date in the form of expressed sequence tags. An international consortium was organized to develop and map gene-based sequence tagged site markers on a set of two radiation hybrid panels and a yeast artificial chromosome library. More than 16,000 human genes have been mapped relative to a framework map that contains about 1000 polymorphic genetic markers. The gene map unifies the existing genetic and physical maps with the nucleotide and protein sequence databases in a fashion that should speed the discovery of genes underlying inherited human disease. The integrated resource is available through a site on the World Wide Web at http://www.ncbi.nlm.nih.gov/SCIENCE96/.
authors.affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, 8600 Rockville Pike, Bethesda, MD 20894, USA.
authors.forename: G D
authors.initials: GD
authors.lastname: Schuler
authors.forename: M S
authors.initials: MS
authors.lastname: Boguski
authors.forename: E A
authors.initials: EA
authors.lastname: Stewart
authors.forename: L D
authors.initials: LD
authors.lastname: Stein
authors.forename: G
authors.initials: G
authors.lastname: Gyapay
authors.forename: K
authors.initials: K
authors.lastname: Rice
authors.forename: R E
authors.initials: RE
authors.lastname: White
authors.forename: P
authors.initials: P
authors.lastname: Rodriguez-Tomé
authors.forename: A
authors.initials: A
authors.lastname: Aggarwal
authors.forename: E
authors.initials: E
authors.lastname: Bajorek
authors.forename: S
authors.initials: S
authors.lastname: Bentolila
authors.forename: B B
authors.initials: BB
authors.lastname: Birren
authors.forename: A
authors.initials: A
authors.lastname: Butler
authors.forename: A B
authors.initials: AB
authors.lastname: Castle
authors.forename: N
authors.initials: N
authors.lastname: Chiannilkulchai
authors.forename: A
authors.initials: A
authors.lastname: Chu
authors.forename: C
authors.initials: C
authors.lastname: Clee
authors.forename: S
authors.initials: S
authors.lastname: Cowles
authors.forename: P J
authors.initials: PJ
authors.lastname: Day
authors.forename: T
authors.initials: T
authors.lastname: Dibling
authors.forename: N
authors.initials: N
authors.lastname: Drouot
authors.forename: I
authors.initials: I
authors.lastname: Dunham
authors.forename: S
authors.initials: S
authors.lastname: Duprat
authors.forename: C
authors.initials: C
authors.lastname: East
authors.forename: C
authors.initials: C
authors.lastname: Edwards
authors.forename: J B
authors.initials: JB
authors.lastname: Fan
authors.forename: N
authors.initials: N
authors.lastname: Fang
authors.forename: C
authors.initials: C
authors.lastname: Fizames
authors.forename: C
authors.initials: C
authors.lastname: Garrett
authors.forename: L
authors.initials: L
authors.lastname: Green
authors.forename: D
authors.initials: D
authors.lastname: Hadley
authors.forename: M
authors.initials: M
authors.lastname: Harris
authors.forename: P
authors.initials: P
authors.lastname: Harrison
authors.forename: S
authors.initials: S
authors.lastname: Brady
authors.forename: A
authors.initials: A
authors.lastname: Hicks
authors.forename: E
authors.initials: E
authors.lastname: Holloway
authors.forename: L
authors.initials: L
authors.lastname: Hui
authors.forename: S
authors.initials: S
authors.lastname: Hussain
authors.forename: C
authors.initials: C
authors.lastname: Louis-Dit-Sully
authors.forename: J
authors.initials: J
authors.lastname: Ma
authors.forename: A
authors.initials: A
authors.lastname: MacGilvery
authors.forename: C
authors.initials: C
authors.lastname: Mader
authors.forename: A
authors.initials: A
authors.lastname: Maratukulam
authors.forename: T C
authors.initials: TC
authors.lastname: Matise
authors.forename: K B
authors.initials: KB
authors.lastname: McKusick
authors.forename: J
authors.initials: J
authors.lastname: Morissette
authors.forename: A
authors.initials: A
authors.lastname: Mungall
authors.forename: D
authors.initials: D
authors.lastname: Muselet
authors.forename: H C
authors.initials: HC
authors.lastname: Nusbaum
authors.forename: D C
authors.initials: DC
authors.lastname: Page
authors.forename: A
authors.initials: A
authors.lastname: Peck
authors.forename: S
authors.initials: S
authors.lastname: Perkins
authors.forename: M
authors.initials: M
authors.lastname: Piercy
authors.forename: F
authors.initials: F
authors.lastname: Qin
authors.forename: J
authors.initials: J
authors.lastname: Quackenbush
authors.forename: S
authors.initials: S
authors.lastname: Ranby
authors.forename: T
authors.initials: T
authors.lastname: Reif
authors.forename: S
authors.initials: S
authors.lastname: Rozen
authors.forename: C
authors.initials: C
authors.lastname: Sanders
authors.forename: X
authors.initials: X
authors.lastname: She
authors.forename: J
authors.initials: J
authors.lastname: Silva
authors.forename: D K
authors.initials: DK
authors.lastname: Slonim
authors.forename: C
authors.initials: C
authors.lastname: Soderlund
authors.forename: W L
authors.initials: WL
authors.lastname: Sun
authors.forename: P
authors.initials: P
authors.lastname: Tabar
authors.forename: T
authors.initials: T
authors.lastname: Thangarajah
authors.forename: N
authors.initials: N
authors.lastname: Vega-Czarny
authors.forename: D
authors.initials: D
authors.lastname: Vollrath
authors.forename: S
authors.initials: S
authors.lastname: Voyticky
authors.forename: T
authors.initials: T
authors.lastname: Wilmer
authors.forename: X
authors.initials: X
authors.lastname: Wu
authors.forename: M D
authors.initials: MD
authors.lastname: Adams
authors.forename: C
authors.initials: C
authors.lastname: Auffray
authors.forename: N A
authors.initials: NA
authors.lastname: Walter
authors.forename: R
authors.initials: R
authors.lastname: Brandon
authors.forename: A
authors.initials: A
authors.lastname: Dehejia
authors.forename: P N
authors.initials: PN
authors.lastname: Goodfellow
authors.forename: R
authors.initials: R
authors.lastname: Houlgatte
authors.forename: J R
authors.initials: JR
authors.lastname: Hudson
authors.forename: S E
authors.initials: SE
authors.lastname: Ide
authors.forename: K R
authors.initials: KR
authors.lastname: Iorio
authors.forename: W Y
authors.initials: WY
authors.lastname: Lee
authors.forename: N
authors.initials: N
authors.lastname: Seki
authors.forename: T
authors.initials: T
authors.lastname: Nagase
authors.forename: K
authors.initials: K
authors.lastname: Ishikawa
authors.forename: N
authors.initials: N
authors.lastname: Nomura
authors.forename: C
authors.initials: C
authors.lastname: Phillips
authors.forename: M H
authors.initials: MH
authors.lastname: Polymeropoulos
authors.forename: M
authors.initials: M
authors.lastname: Sandusky
authors.forename: K
authors.initials: K
authors.lastname: Schmitt
authors.forename: R
authors.initials: R
authors.lastname: Berry
authors.forename: K
authors.initials: K
authors.lastname: Swanson
authors.forename: R
authors.initials: R
authors.lastname: Torres
authors.forename: J C
authors.initials: JC
authors.lastname: Venter
authors.forename: J M
authors.initials: JM
authors.lastname: Sikela
authors.forename: J S
authors.initials: JS
authors.lastname: Beckmann
authors.forename: J
authors.initials: J
authors.lastname: Weissenbach
authors.forename: R M
authors.initials: RM
authors.lastname: Myers
authors.forename: D R
authors.initials: DR
authors.lastname: Cox
authors.forename: M R
authors.initials: MR
authors.lastname: James
authors.forename: D
authors.initials: D
authors.lastname: Bentley
authors.forename: P
authors.initials: P
authors.lastname: Deloukas
authors.forename: E S
authors.initials: ES
authors.lastname: Lander
authors.forename: T J
authors.initials: TJ
authors.lastname: Hudson
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002460:Cell Line; D002874:Chromosome Mapping; D018244:Chromosomes, Artificial, Yeast; D003195:Computer Communication Networks; D018076:DNA, Complementary / Q000235:genetics; D016208:Databases, Factual; D015870:Gene Expression; D005819:Genetic Markers; D015894:Genome, Human; D016045:Human Genome Project; D006801:Humans; D005810:Multigene Family; D012333:RNA, Messenger / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid; D016324:Sequence Tagged Sites
chemical_list: D018076:DNA, Complementary; D005819:Genetic Markers; D012333:RNA, Messenger