title: Enkephalin positive sites in the developing human cerebellum.
abstract: Enkephalin (ENK) positive sites in the developing human cerebellum (gestation ages 18 weeks to 30 weeks) were studied by immunohistochemistry (ABC method). Positive reactions were registered as early as 20 weeks of gestation and initially in the deep cerebellar nuclei. By 23 weeks some mossy fibers exhibited positivity and by 27 weeks some climbing fibers as well as a few Purkinje basket, golgi and granule cells were also positive. This result indicated that the human cerebellum possesses ENK positive fibers and neurons before birth.
authors.affiliation: Department of Anatomy, Chinese University of Hong Kong, Shatin, Hong Kong.
authors.forename: D T
authors.initials: DT
authors.lastname: Yew
authors.forename: W W
authors.initials: WW
authors.lastname: Li
authors.forename: T K
authors.initials: TK
authors.lastname: Lam
mesh_terms: D002525:Cerebellar Cortex / Q000033:anatomy & histology / Q000196:embryology / Q000378:metabolism; D002531:Cerebellum / Q000033:anatomy & histology / Q000196:embryology* / Q000378:metabolism*; D004745:Enkephalins / Q000378:metabolism*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009412:Nerve Fibers / Q000502:physiology; D011247:Pregnancy
chemical_list: D004745:Enkephalins