Novel tetranucleotide repeat polymorphism in the human adenosine deaminase gene: interethnic comparison of three major human groups.
A new tetranucleotide repeat polymorphism was revealed at the human adenosine deaminase (ADA) locus by using the polymerase chain reaction and denaturing polyacrylamide gel electrophoresis. Allele frequencies were estimated in seven populations from three major ethnic groups. Heterozygosity values were calculated and found to differ significantly between Africans and non-Africans.
Scozzari
R
R
Dipartimento di Genetica e Biologia Molecolare, Università La Sapienza, Rome, Italy.
Cruciani
F
F
Santolamazza
P
P
Parra
E
E
Sellitto
D
D
Modiano
D
D
Meloni
G
G
Cai
W
W
Moral
P
P
D000243:Adenosine Deaminase / Q000032:analysis / Q000235:genetics*; D001483:Base Sequence; D005006:Ethnicity / Q000235:genetics*; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics*; D011153:Population
D000243:Adenosine Deaminase