An acquired inhibitor to factor X in a pediatric patient with extensive burns.
OBJECTIVE
An acquired inhibitor to factor X is an uncommon clinical finding in the pediatric population. We report the development of this type of inhibitor in a pediatric patient with extensive burns.


METHODS
The patient's clinical course was complicated by persistent blood loss from the burn site.


RESULTS
Characterization of the inhibitor demonstrated that it bound to the light chain of factor X.


CONCLUSIONS
The inhibitor disappeared after treatment with i.v. immunoglobulin.
Matsunaga
A T
AT
Department of Hematology-Oncology, Children's Hospital Oakland, CA 94609, USA.
Shafer
F E
FE
D000941:Antigens / Q000032:analysis; D002056:Burns / Q000097:blood*; D002648:Child; D005170:Factor X / Q000032:analysis / Q000037:antagonists & inhibitors*; D006801:Humans; D008297:Male
D000941:Antigens; C010515:factor X antigen; D005170:Factor X