The effects of decyl aurachins C and D on the respiratory electron flow of facultative phototrophic bacteria.
Decyl aurachins C and D are two synthetic compounds related to the natural products aurachins C and D extracted from Stigmatella aurantiaca. Titrations of a range of partial respiratory activities in membranes from facultative phototrophs indicate that decyl aurachin C is more effective than aurachin D in inhibiting the quinol oxidase. Decyl aurachin C also affects the NADH-ubiquinone oxidoreductase of Rhodobacter capsulatus and the cytochrome bc1 complexes of Rb.capsulatus and Rhodospirillum centenum. Titration of the light-induced respiration in Rsp.centenum allowed us to estimate an upper limit for the ubiquinol oxidase concentration of 1.5 +/- 0.2 nmol/mg protein, or a ubiquinol oxidase/cytochrome c oxidase ratio of 3:1.
Romagnoli
S
S
Department of Biology, Univ. of Bologna, Italy.
Oettmeier
W
W
Zannoni
D
D
D001419:Bacteria / Q000187:drug effects*; D018407:Bacterial Physiological Phenomena; D003486:Cyanides / Q000494:pharmacology; D008027:Light; D010088:Oxidoreductases / Q000378:metabolism; D010101:Oxygen Consumption / Q000187:drug effects*; D015363:Quinolones / Q000494:pharmacology*
D003486:Cyanides; D015363:Quinolones; C103369:decyl aurachin C; C103370:decyl aurachin D; D010088:Oxidoreductases; C022691:succinate oxidase