[A model of the structure of the receptor apparatus of HIV target cells (1)].
A model is proposed and well based of structure of the receptor apparatus of interacting HIV target cells: Langerhans cells (LC) and helper cells (HC)--designed to explain feasibility of realizing a double activation signal, together with some features of immune pathogenesis of HIV-infection (morphofunctional abnormalities in certain subpopulations of the immune system such as HC, suppressor cells, killer cells, natural killers, lymph cells, macrophages, LC), as well as immunogenetic predisposition to AIDS.
Volianskiĭ
Iu L
IuL
Telepneva
L G
LG
Vasil'ev
N V
NV
D015704:CD4 Antigens / Q000276:immunology / Q000648:ultrastructure; D016827:CD8 Antigens / Q000276:immunology / Q000648:ultrastructure; D002450:Cell Communication; D006801:Humans; D007801:Langerhans Cells / Q000166:cytology / Q000276:immunology; D008954:Models, Biological; D008961:Models, Structural; D015728:Receptors, HIV / Q000276:immunology / Q000648:ultrastructure*; D013329:Structure-Activity Relationship; D013499:Surface Properties; D006377:T-Lymphocytes, Helper-Inducer / Q000166:cytology / Q000276:immunology
D015704:CD4 Antigens; D016827:CD8 Antigens; D015728:Receptors, HIV