title: [Basic concepts in molecular genetics].
abstract: Recombinant DNA technology has made great strides in recent years, enabling researchers to manipulate genetic material for the study of fundamental phenomena in biology and pathological processes that are well defined in clinical practice. Advances have been made toward defining some of these diseases in molecular biological terms with a diagnostic precision that was unimaginable only a few years ago. From a theoretical standpoint, the technical possibilities for studying the genome are unlimited, obliging the medical profession to focus on the molecular level, not only to further understanding of the pathophysiological processes that underpin disease but also to consider their diagnostic and therapeutic implications.
authors.affiliation: Unidad de Genética Molecular, Hospital de la Santa Creu i Sant Pau, Barcelona.
authors.forename: M
authors.initials: M
authors.lastname: Baiget
mesh_terms: D015139:Blotting, Southern; D004262:DNA Restriction Enzymes; D004274:DNA, Recombinant; D005838:Genotype; D006801:Humans; D008967:Molecular Biology; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
chemical_list: D004274:DNA, Recombinant; D004262:DNA Restriction Enzymes