Scoliosis in cerebral gigantism, Sotos syndrome. A case report.
METHODS
This retrospective study reviewed five patients with scoliosis associated with cerebral gigantism (Sotos syndrome).


OBJECTIVE
To clarify the clinical characteristics and progression of scoliosis in patients with cerebral gigantism. SUMMARY OF BACKGROUND DATA. Little has been reported about spinal deformity in this syndrome.


METHODS
The records and radiographs of five patients were reviewed.


RESULTS
Scoliosis was first noticed at the age of 5 years in one case and at 6-16 months in the others. Their curve patterns were not consistent. Cobb's angles increased rapidly by 4 years of age and after 8 years of age despite attempts at bracing.


CONCLUSIONS
Excessive growth in infancy and growth-spurt period after 8 years of age may be related to the rapid progression of scoliosis in the same period.
Haga
N
N
Department of Pediatric Orthopedics, Shizuoka Children's Hospital, Japan.
Nakamura
S
S
Shimode
M
M
Yanagisako
Y
Y
Iwaya
T
T
D001921:Brain / Q000002:abnormalities*; D002675:Child, Preschool; D005260:Female; D005877:Gigantism / Q000150:complications*; D006128:Growth / Q000502:physiology; D006801:Humans; D007223:Infant; D008297:Male; D011859:Radiography; D012189:Retrospective Studies; D012600:Scoliosis / Q000150:complications* / Q000601:surgery; D013131:Spine / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery