title: Chicken extract stimulates haemoglobin restoration in iron deficient rats.
abstract: Chicken essence is widely used as a traditional remedy for several ailments including anaemia. To test this claim for objective evidence, a series of experiments was carried out in anaemic rats by supplementing iron deficient diets with either liquid or lyophilised essence, which contains mainly protein and peptides (83 mg/ml) and free amino acids (3.1 mg/ml), very little iron (1 microgram/ml), and no fat. Haemoglobin returned to normal significantly more rapidly in rats supplemented with ad libitum liquid BEC over a period of up to 27 days compared with controls fed only water in addition to the ad libitum iron deficient diet. Haemoglobin was also significantly increased after 1 week in animals fed ad libitum diets supplemented with lyophilised chicken essence than with controls fed the unsupplemented diet. The effect was greater with supplementation at the level of 0.2% than at 1% lyophilised essence. The results indicate that the effects were mediated by increased appetite and by enhanced availability of food iron. These studies provide objective evidence for the traditional belief that chicken essence remedies anaemia.
authors.affiliation: Department of Nutrition and Dietetics, Kings College, University of London, UK.
authors.forename: C
authors.initials: C
authors.lastname: Geissler
authors.forename: M
authors.initials: M
authors.lastname: Boroumand-Naini
authors.forename: M
authors.initials: M
authors.lastname: Harada
authors.forename: T
authors.initials: T
authors.lastname: Iino
authors.forename: K
authors.initials: K
authors.lastname: Hirai
authors.forename: Y
authors.initials: Y
authors.lastname: Suwa
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: S
authors.initials: S
authors.lastname: Iwata
mesh_terms: D018798:Anemia, Iron-Deficiency / Q000097:blood* / Q000178:diet therapy* / Q000378:metabolism; D000818:Animals; D001682:Biological Availability; D002645:Chickens; D005260:Female; D005527:Food, Fortified; D006454:Hemoglobins / Q000096:biosynthesis*; D019266:Iron, Dietary / Q000378:metabolism*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D013997:Time Factors
chemical_list: D006454:Hemoglobins; D019266:Iron, Dietary