title: Induction of cytochrome P450 3A by metyrapone in human hepatocyte culture.
authors.affiliation: DH Dept Toxicology, St Bartholomew's Hospital Medical College, London, UK.
authors.forename: M C
authors.initials: MC
authors.lastname: Wright
authors.forename: P
authors.initials: P
authors.lastname: Maurel
authors.forename: A J
authors.initials: AJ
authors.lastname: Paine
mesh_terms: D001189:Aryl Hydrocarbon Hydroxylases; D002478:Cells, Cultured; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis*; D004790:Enzyme Induction / Q000187:drug effects; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008797:Metyrapone / Q000494:pharmacology*; D010089:Oxidoreductases, N-Demethylating / Q000096:biosynthesis*
chemical_list: D003577:Cytochrome P-450 Enzyme System; D001189:Aryl Hydrocarbon Hydroxylases; D051544:Cytochrome P-450 CYP3A; D010089:Oxidoreductases, N-Demethylating; D008797:Metyrapone