[Changes in the functional state of the lysosomal apparatus of the peripheral blood neutrophilic leukocytes in rabbits under the action of immobilization with thyroid hormone deficiency].
Experiments carried out on rabbits under conditions of the oppression of the thyroid system have revealed that the 12-hour immobilization causes neutrophilic leukocytosis in the peripheral blood, degranulation of neutrophils and intensification of acid phosphatase activity. As against the control group these changes were less marked and lasted for a longer period of time. A conclusion is made that thyroid hormones are necessary components in formation of an adaptive syndrome under the influence of immobilization.
Lunina
N V
NV
Honchar
O O
OO
D000135:Acid Phosphatase / Q000097:blood / Q000187:drug effects; D000818:Animals; D013956:Antithyroid Agents / Q000494:pharmacology; D015550:Cell Degranulation / Q000187:drug effects; D008247:Lysosomes / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D008297:Male; D008713:Methimazole / Q000494:pharmacology; D009504:Neutrophils / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D011817:Rabbits; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000097:blood / Q000503:physiopathology; D013963:Thyroid Hormones / Q000172:deficiency*; D013997:Time Factors
D013956:Antithyroid Agents; D013963:Thyroid Hormones; D008713:Methimazole; D000135:Acid Phosphatase