Von Wille-brand's disease in UK dobermanns: possible correlation of a polymorphic DNA marker with disease status.
Ninety-one dobermanns have been typed for a polymorphic microsatellite DNA marker situated within an intron of the von Willebrand factor gene and the alleles correlated with von Wille-brand's disease status. Two alleles were identified, one associated only with the normal gene and the other with both normal and disease genes.
Holmes
N G
NG
Centre for Preventive Medicine, Animal Health Trust, Newmarket, Suffolk.
Shaw
S C
SC
Dickens
H F
HF
Coombes
L M
LM
Ryder
E J
EJ
Littlewood
J D
JD
Binns
M M
MM
D000483:Alleles; D000818:Animals; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D014842:von Willebrand Diseases / Q000235:genetics / Q000662:veterinary*; D014841:von Willebrand Factor / Q000235:genetics*
D014841:von Willebrand Factor