title: Use of recombinant tissue-type plasminogen activator to treat massive pulmonary embolism after cesarean section: a case report.
abstract: A 30-year-old primigravida, delivering by cesarean section, went into shock with cardiac arrest due to pulmonary thromboembolism. Thrombolytic therapy with recombinant-tissue-type plasminogen activator (rt-PA) induced a rapid improvement in both the hemodynamic and respiratory conditions. This case shows the marked efficacy of rt-PA in treating massive pulmonary thromboembolism. Close attention must be given to the patient in such a case, however, because the risk of hemorrhagic complication exists.
authors.affiliation: Department of Obstetrics and Gynecology, Shimonoseki City Hospital, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Onoyama
authors.forename: M
authors.initials: M
authors.lastname: Minamitani
authors.forename: H
authors.initials: H
authors.lastname: Takeuchi
authors.forename: S
authors.initials: S
authors.lastname: Sakai
authors.forename: H
authors.initials: H
authors.lastname: Eguchi
mesh_terms: D000328:Adult; D002585:Cesarean Section; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D011183:Postoperative Complications; D011247:Pregnancy; D011644:Puerperal Disorders / Q000188:drug therapy*; D011655:Pulmonary Embolism / Q000188:drug therapy*; D011994:Recombinant Proteins / Q000627:therapeutic use; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator