Cytotoxic xanthones from Garcinia hanburyi.
Eleven novel cytotoxic xanthones, gambogin, morellin dimethyl acetal, isomoreollin B, moreollic acid, gambogenic acid, gambogenin, isogambogenin, desoxygambogenin, gambogenin dimethyl acetal, gambogellic acid and hanburin were isolated together with four known xanthones, gambogic acid, isomorellin, morellic acid and desoxymorellin, from the dry latex of Garcinia hanburyi. The structures were elucidated by a detailed spectroscopic analysis.
Asano
J
J
Laboratory of Bio-organic Chemistry, Tokyo University of Agriculture and Technology, Japan.
Chiba
K
K
Tada
M
M
Yoshii
T
T
D002460:Cell Line; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D010946:Plants, Medicinal / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013729:Terpenes / Q000737:chemistry / Q000494:pharmacology*; D014966:Xanthenes / Q000737:chemistry / Q000302:isolation & purification*; D044004:Xanthones / Q000737:chemistry / Q000494:pharmacology*
D013729:Terpenes; D014966:Xanthenes; D044004:Xanthones; C045863:neo-gambogic acid