Some immunological parameters in workers occupationally exposed to n-hexane.
1. To estimate the quantitative relation between exposure to airborne n-hexane and various markers of immune function, 35 male workers were examined and compared with unexposed controls. 2. Urinary 2,5-hexanedione concentrations were significantly higher in the exposed group than in the unexposed. 3. A significant suppression was observed in the serum immunoglobulin (IgG, IgM and IgA) levels between two populations. Also, a significant correlation was found between urinary 2,5-hexanedione concentrations and serum Ig level of the exposed group. 4. No significant difference between white blood cell counts was found in the two groups.
Karakaya
A
A
Department of Toxicology, Ankara University, Turkey.
Yücesoy
B
B
Burgaz
S
S
Sabir
H U
HU
Karakaya
A E
AE
D000269:Adhesives; D000328:Adult; D000367:Age Factors; D005260:Female; D006586:Hexanes / Q000097:blood / Q000633:toxicity* / Q000652:urine; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D007958:Leukocyte Count / Q000187:drug effects*; D008297:Male; D016273:Occupational Exposure / Q000009:adverse effects* / Q000032:analysis
D000269:Adhesives; D006586:Hexanes; D007136:Immunoglobulins; C026385:n-hexane