[The regulatory characteristics of creatine kinase activity in the skeletal muscle of piglets in the neonatal period].
The creatine kinase activity in the skeletal muscles of one-day-old piglets is shown to be 1.3 times lower than that of five-day-old animals. The content of isoenzymes MM, MB and BB of creatine kinase in the skeletal muscles of one-and five-day-old piglets amounts to 25.8 and 30.4, 58.2 and 24.2%, of the total content of the enzyme, respectively. Insulin induces variations in the isoenzyme spectrum of creatine kinase in the skeletal muscles of piglets, which are more pronounced in one-day-old piglets, than in five-day-old animals. Cortisol seems to have no significant effect on the isoenzyme spectrum of creatine kinase in the skeletal muscles of piglets of both age groups. However, under conditions of starvation, the activity of creatine kinase in the skeletal muscles of piglets of both age groups falls, particularly in one-day-old animals.
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Snittyns'kyĭ
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D000375:Aging / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D000831:Animals, Newborn; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D003402:Creatine Kinase / Q000187:drug effects / Q000378:metabolism*; D005215:Fasting / Q000378:metabolism; D006854:Hydrocortisone / Q000494:pharmacology; D007004:Hypoglycemic Agents / Q000494:pharmacology; D007328:Insulin / Q000494:pharmacology; D007527:Isoenzymes; D018482:Muscle, Skeletal / Q000187:drug effects / Q000201:enzymology*; D013552:Swine / Q000378:metabolism*
D000893:Anti-Inflammatory Agents; D007004:Hypoglycemic Agents; D007328:Insulin; D007527:Isoenzymes; D003402:Creatine Kinase; D006854:Hydrocortisone