title: [The role of calcitonin gene-related peptide fragments in regulating the microcirculation in rats].
abstract: Fragments of the calcitonin gene-related neuropeptide's molecule with the amino acid sequence 1-9, 10-20, 15-24, 20-29 and 30-37, were studied. The fragment 20-29 revealed the greatest biological activity: it induced a dose-dependent drop of arterial pressure in i.v. administration, enlarges arterial and venous microvessels when locally applied.
authors.forename: V A
authors.initials: VA
authors.lastname: Akopian
authors.forename: N V
authors.initials: NV
authors.lastname: Balashov
authors.forename: S V
authors.initials: SV
authors.lastname: Burov
authors.forename: G P
authors.initials: GP
authors.lastname: Vlasov
authors.forename: V I
authors.initials: VI
authors.lastname: Korol'kov
mesh_terms: D000818:Animals; D015740:Calcitonin Gene-Related Peptide / Q000494:pharmacology / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D008208:Lymphatic System / Q000187:drug effects / Q000502:physiology; D008297:Male; D008643:Mesentery / Q000098:blood supply* / Q000187:drug effects; D008833:Microcirculation / Q000187:drug effects / Q000502:physiology; D010446:Peptide Fragments / Q000494:pharmacology / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D013329:Structure-Activity Relationship
chemical_list: D010446:Peptide Fragments; D015740:Calcitonin Gene-Related Peptide