Fatal accidental dibucaine poisoning in children.
Dibucaine is a potent amide anesthetic available in over-the-counter preparations. Compared with lidocaine, substantially lower doses of dibucaine may result in seizures, dysrhythmias, and death. We present three fatal cases of accidental dibucaine ingestion in children and discuss the toxicity, treatment, and prevention of such ingestions.
Dayan
P S
PS
Children's National Medical Center, George Washington University School of Medicine, Washington DC, USA.
Litovitz
T L
TL
Crouch
B I
BI
Scalzo
A J
AJ
Klein
B L
BL
D000284:Administration, Oral; D000779:Anesthetics, Local / Q000506:poisoning*; D002675:Child, Preschool; D003992:Dibucaine / Q000506:poisoning*; D062787:Drug Overdose; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009824:Ointments
D000779:Anesthetics, Local; D009824:Ointments; D003992:Dibucaine