Drug-dependent exercise-induced anaphylaxis.
Exercise-induced anaphylaxis (EIA) is well known and may be food-dependent. We describe a patient with a history of anaphylaxis during exercise after taking nafylpropion acid (Naprosyne), a nonsteroidal anti-inflammatory drug. An exercise-challenge test after Naprosyne intake induced bronchoconstriction. The combination of history and challenge tests suggests that intolerance or allergy to drugs may present as EIA.
van Wijk
R G
RG
Department of Allergology, University Hospital Rotterdam, Netherlands.
de Groot
H
H
Bogaard
J M
JM
D000293:Adolescent; D000707:Anaphylaxis / Q000139:chemically induced / Q000209:etiology*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D015444:Exercise; D005260:Female; D006801:Humans; D009288:Naproxen / Q000009:adverse effects*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D009288:Naproxen