title: Ultraweak biophoton emission imaging of transplanted bladder cancer.
abstract: Biophoton emission or spontaneous ultraweak light emission has been observed from almost all living organisms, with intensities ranging from 10(-19) to 10(-16) W/cm2. The measurement of biophoton emission offers the attractive possibility of noninvasive monitoring of the underlying physiological function of a living system. In the present study, ultraweak biophoton emission from mice with transplanted bladder cancer was detected by a two-dimensional photon-counting system. Photon counts were observed to be 1.51-4.73 times higher from the regions of untreated tumor than from normal regions. Our study suggests that this novel technique may be applicable to the diagnosis of superficial tumors.
authors.affiliation: Department of Urology, Kanazawa University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Amano
authors.forename: M
authors.initials: M
authors.lastname: Kobayashi
authors.forename: B
authors.initials: B
authors.lastname: Devaraj
authors.forename: M
authors.initials: M
authors.lastname: Usa
authors.forename: H
authors.initials: H
authors.lastname: Inaba
mesh_terms: D000818:Animals; D004867:Equipment Design; D005260:Female; D051379:Mice; D008819:Mice, Nude; D009368:Neoplasm Transplantation; D017785:Photons; D013679:Technology, Radiologic / Q000295:instrumentation; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000503:physiopathology*