title: Pituitary apoplexy after subtotal thyroidectomy in an acromegalic patient with a large goiter.
abstract: A case of pituitary apoplexy occurring after subtotal thyroidectomy in an acromegalic woman with a large adenomatous goiter is described. The patient had severe apnea because the large goiter was causing airway compression. Prior to the planned hypophysectomy, a subtotal thyroidectomy was performed to relieve tracheal stenosis. Shortly after the operation, the patient developed a headache that lasted for several days. The serum levels of growth hormone and somatomedin-C spontaneously normalized seventeen days after this episode and have remained normal for two years. Pituitary apoplexy was thought to have caused the observed results without deterioration of the pituitary function.
authors.affiliation: Department of Internal Medicine, Asahi General Hospital, Chiba.
authors.forename: K
authors.initials: K
authors.lastname: Kato
authors.forename: M
authors.initials: M
authors.lastname: Nobori
authors.forename: Y
authors.initials: Y
authors.lastname: Miyauchi
authors.forename: M
authors.initials: M
authors.lastname: Ohnisi
authors.forename: S
authors.initials: S
authors.lastname: Yoshida
authors.forename: S
authors.initials: S
authors.lastname: Oya
authors.forename: S
authors.initials: S
authors.lastname: Tomita
authors.forename: T
authors.initials: T
authors.lastname: Kino
mesh_terms: D000172:Acromegaly / Q000150:complications*; D000236:Adenoma / Q000098:blood supply / Q000150:complications* / Q000378:metabolism; D000328:Adult; D000568:Amenorrhea / Q000209:etiology; D001763:Blepharoptosis / Q000209:etiology; D003920:Diabetes Mellitus / Q000209:etiology; D004417:Dyspnea / Q000209:etiology; D005260:Female; D006045:Goiter, Substernal / Q000150:complications* / Q000601:surgery; D006261:Headache / Q000209:etiology; D019382:Human Growth Hormone / Q000097:blood / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007334:Insulin-Like Growth Factor I / Q000032:analysis / Q000378:metabolism; D010899:Pituitary Apoplexy / Q000150:complications*; D010900:Pituitary Diseases / Q000150:complications*; D010902:Pituitary Gland / Q000098:blood supply; D010911:Pituitary Neoplasms / Q000098:blood supply / Q000150:complications* / Q000378:metabolism; D011183:Postoperative Complications; D012075:Remission, Spontaneous; D013965:Thyroidectomy
chemical_list: D019382:Human Growth Hormone; D007334:Insulin-Like Growth Factor I