title: [Prevalence of human herpesvirus 7 in Mexican blood donors].
abstract: The human herpes virus 7 (HHV-7) has been recently isolated from CD4 cells of healthy persons. The present study describes the antibody prevalence of this virus in a healthy Mexican population. Two hundred blood samples from candidates for blood donation at the Hospital General de Mexico were studied with the indirect immunofluorescence test (IFA) in HHV-7 infected SupT1 cells. The testing was done in the University of Cologne, Germany; 167 were males and 33 female; the donors came from 12 of the 31 states in the Mexican republican, predominantly from Mexico City (60.5%) and the State of Mexico (28%). Their mean age was 29.2 years. All but three samples were positive to the HHV-7 (98.5% positivity). Nearly 85% had high titers (> or = 1:80). Other serology testing in the samples revealed 1% positive tests to hepatitis B, 2% to syphilis, and 0.5% to brucella. Hepatitis C and the HIV test were negative in all. The high prevalence of HHV-7 in our donor population should be further studied in order to determine titers indicative of an active infection and of their association with illnesses.
authors.affiliation: Banco de sangre, Hospital General, Fac. de Medicina, UNAM, México.
authors.forename: J
authors.initials: J
authors.lastname: Rojo Medina
authors.forename: G R
authors.initials: GR
authors.lastname: Krueger
authors.forename: R
authors.initials: R
authors.lastname: Bonifaz Gracias
authors.forename: Z
authors.initials: Z
authors.lastname: Berneman
authors.forename: B
authors.initials: B
authors.lastname: Koch
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood* / Q000276:immunology; D001782:Blood Donors; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006566:Herpesviridae Infections / Q000097:blood / Q000453:epidemiology*; D015654:Herpesvirus 6, Human / Q000276:immunology / Q000302:isolation & purification; D016199:Herpesvirus 7, Human / Q000276:immunology / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D015995:Prevalence; D016036:Seroepidemiologic Studies
chemical_list: D000914:Antibodies, Viral