Induction of cytochrome P450 3A by metyrapone in human hepatocyte culture.
Wright
M C
MC
DH Dept Toxicology, St Bartholomew's Hospital Medical College, London, UK.
Maurel
P
P
Paine
A J
AJ
D001189:Aryl Hydrocarbon Hydroxylases; D002478:Cells, Cultured; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000096:biosynthesis*; D004790:Enzyme Induction / Q000187:drug effects; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000201:enzymology*; D008797:Metyrapone / Q000494:pharmacology*; D010089:Oxidoreductases, N-Demethylating / Q000096:biosynthesis*
D003577:Cytochrome P-450 Enzyme System; D001189:Aryl Hydrocarbon Hydroxylases; D051544:Cytochrome P-450 CYP3A; D010089:Oxidoreductases, N-Demethylating; D008797:Metyrapone