Focal residual contrast media in the kidney 24 hours after angiography.
OBJECTIVE
To examine the relationship between focal renal cortical retention (FRCR) and contrast-associated nephropathy (CAN).


METHODS
We investigated the incidence of both phenomena in 105 patients. CAN was defined as an increase in the creatinine level > 0.3 mg/dl and > 20% on days 1, 3, or 7. We compared predisposing factors for FRCR and CAN. Serum creatinine and blood urea nitrogen (BUN) for renal function were determined on the morning of the day of the angiography. The BUN/creatinine ratio was used as an indicator of the degree of hydration.


RESULTS
FRCR was demonstrated in 17 patients (16%) by delayed CT 24 h after angiography, and CAN was found in 16 patients (15%). No significant relationship between CAN and FRCR was found. We found a correlation between high total volumes of contrast and FRCR. Advanced age, high blood urea nitrogen, high creatinine, and dehydration were risk factors for CAN.


CONCLUSIONS
Delayed CT showed a higher incidence of injury to the renal parenchyma than previously detected by conventional radiography.
Yamazaki
H
H
Department of Radiation Oncology, Osaka University Medical School, Japan.
Oi
H
H
Matsushita
M
M
Koizumi
M
M
Kagawa
K
K
Tanaka
E
E
Murayama
S
S
Nose
T
T
Teshima
T
T
Inoue
T A
TA
Inoue
T O
TO
D000792:Angiography; D015984:Causality; D003287:Contrast Media / Q000009:adverse effects*; D005260:Female; D006801:Humans; D015994:Incidence; D007672:Kidney Cortex / Q000000981:diagnostic imaging*; D007674:Kidney Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000453:epidemiology; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D013997:Time Factors; D014057:Tomography, X-Ray Computed
D003287:Contrast Media