title: Von Wille-brand's disease in UK dobermanns: possible correlation of a polymorphic DNA marker with disease status.
abstract: Ninety-one dobermanns have been typed for a polymorphic microsatellite DNA marker situated within an intron of the von Willebrand factor gene and the alleles correlated with von Wille-brand's disease status. Two alleles were identified, one associated only with the normal gene and the other with both normal and disease genes.
authors.affiliation: Centre for Preventive Medicine, Animal Health Trust, Newmarket, Suffolk.
authors.forename: N G
authors.initials: NG
authors.lastname: Holmes
authors.forename: S C
authors.initials: SC
authors.lastname: Shaw
authors.forename: H F
authors.initials: HF
authors.lastname: Dickens
authors.forename: L M
authors.initials: LM
authors.lastname: Coombes
authors.forename: E J
authors.initials: EJ
authors.lastname: Ryder
authors.forename: J D
authors.initials: JD
authors.lastname: Littlewood
authors.forename: M M
authors.initials: MM
authors.lastname: Binns
mesh_terms: D000483:Alleles; D000818:Animals; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D014842:von Willebrand Diseases / Q000235:genetics / Q000662:veterinary*; D014841:von Willebrand Factor / Q000235:genetics*
chemical_list: D014841:von Willebrand Factor