Cefotiam-induced contact urticaria syndrome: an occupational condition in Japanese nurses.
A case of occupational contact urticaria syndrome caused by cefotiam dihydrochloride (CTM) in a Japanese nurse is reported. The patient had become sensitized to CTM through the process of preparing antibiotics 8 months before she developed symptoms. A review of the literature revealed 13 similar cases, all involving Japanese nurses, reported since CTM became available in Japan.
Shimizu
S
S
Division of Dermatology, Kawasaki City Hospital, Japan.
Chen
K R
KR
Miyakawa
S
S
D000328:Adult; D015310:Cefotiam / Q000009:adverse effects*; D002511:Cephalosporins / Q000009:adverse effects*; D003877:Dermatitis, Contact / Q000175:diagnosis / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D007564:Japan; D009726:Nurses; D014581:Urticaria / Q000139:chemically induced*
D002511:Cephalosporins; D015310:Cefotiam