The cyclosporins.
This review presents the progress and some aspects achieved during recent years with cyclosporin sources, chemistry, biological activities, side effects, biosynthesis and metabolism. Although incomplete the results indicate future research trends and some white spots to be studied in the near future to afford unique insights into cell biology and to improve the search for similar and even more specific agents based on rational drug design.
Rehácek
Z
Z
Konĕvova 93, Prague, Czech Republic.
D000595:Amino Acid Sequence; D000818:Animals; D003524:Cyclosporins / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D007166:Immunosuppressive Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D008969:Molecular Sequence Data; D015394:Molecular Structure
D003524:Cyclosporins; D007166:Immunosuppressive Agents