title: Intraosseous plating with absorbable self-reinforced poly-L-lactide plates in the fixation of distal femoral osteotomies on rabbits.
abstract: Osteotomies of distal femur were fixed by intraosseous self-reinforced poly-L-lactic acid (SR-PLLA) plates in 29 adult rabbits. The follow-up times were from 3 to 24 weeks. After sacrifice, radiological, histological, microradiographic, and oxytetracycline fluorescence studies were performed. Although radiographically no redisplacements were found, in 12 weeks two fixations were broken and a fibrotic nonunion was observed in one case. At 24 weeks full bone consolidation was seen in all except one osteotomy. No foreign-body reactions were observed. The present article is the first report on successful application of absorbable plates for intraosseous fixation of weight-bearing bone osteotomies. The present investigation demonstrated that the SR-PLLA plates were suitable for the fixation of cancellous bone osteotomies in rabbits.
authors.affiliation: Helsinki University Central Hospital, Finland.
authors.forename: K
authors.initials: K
authors.lastname: Koskikare
authors.forename: E
authors.initials: E
authors.lastname: Hirvensalo
authors.forename: H
authors.initials: H
authors.lastname: Pätiälä
authors.forename: P
authors.initials: P
authors.lastname: Rokkanen
authors.forename: T
authors.initials: T
authors.lastname: Pohjonen
authors.forename: P
authors.initials: P
authors.lastname: Törmälä
authors.forename: G
authors.initials: G
authors.lastname: Lob
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000493:pharmacokinetics; D005260:Female; D005264:Femoral Fractures / Q000473:pathology / Q000628:therapy*; D005269:Femur / Q000473:pathology; D005592:Fracture Fixation; D008297:Male; D008422:Materials Testing; D010027:Osteotomy; D010118:Oxytetracycline / Q000493:pharmacokinetics; D011091:Polyesters; D019736:Prostheses and Implants; D011817:Rabbits
chemical_list: D000900:Anti-Bacterial Agents; D011091:Polyesters; C033616:poly(lactide); D010118:Oxytetracycline