Specificity of neuropsychological impairment in obsessive-compulsive disorder: a comparison with social phobic and normal control subjects.
Specificity of neuropsychological dysfunction in obsessive-compulsive disorder (OCD) was assessed by comparing neuropsychological performance in 65 OCD patients, 17 social phobic patients, and 32 normal control subjects. Although both patient groups showed visual constructional impairment relative to normal subjects, only patients with social phobia showed executive dysfunction. Nonconcurrent state anxiety did not correlate with neuropsychological performance. Among anxiety disorders, neuropsychological dysfunction may not be specific to OCD, but the functions implicated may differ across patient groups.
Cohen
L J
LJ
Department of Psychiatry, Mount Sinai School of Medicine, New York 10029, USA
Hollander
E
E
DeCaria
C M
CM
Stein
D J
DJ
Simeon
D
D
Liebowitz
M R
MR
Aronowitz
B R
BR
D000293:Adolescent; D000328:Adult; D001288:Attention / Q000502:physiology; D005260:Female; D006801:Humans; D007361:Intelligence Tests; D008297:Male; D008568:Memory / Q000502:physiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D009771:Obsessive-Compulsive Disorder / Q000503:physiopathology / Q000523:psychology*; D010698:Phobic Disorders / Q000503:physiopathology / Q000523:psychology*; D013028:Space Perception / Q000502:physiology; D014796:Visual Perception / Q000502:physiology