title: Brucellosis and polyneuroradiculomyeloencephalitis. A case report.
abstract: Reports on simultaneous central and peripheral nervous system involvement in a patient with brucellosis are very rare. We report of one young female patient with a long history of consumption of non-pasteurized dairy products in which clinical and laboratory findings confirmed the existence of an active brucellosis with nervous system impairment. Cerebrospinal fluid (CSF) analyses were negative. Electrophysiology and positive findings on sural nerve biopsy complemented the diagnosis of polyneuroradiculomyeloencephalitis. Treatment with a combination of doxycycline and rifampin for 2 months was successfully applied. No relapse or sequelae occurred in the patient after 12 months of follow up.
authors.affiliation: Departamento de Neurología y Neurocirugía, Laboratorio de Microcirugía y Cirugía y de Base de Cráneo, Hospital Civil de Guadalajara, Guadalajara, Jal., México.
authors.forename: R
authors.initials: R
authors.lastname: Riestra-Castañeda
authors.forename: A
authors.initials: A
authors.lastname: González-Garrido
authors.forename: S
authors.initials: S
authors.lastname: González-Cornejo
mesh_terms: D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood; D002002:Brucella / Q000276:immunology; D002006:Brucellosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000635:transmission; D003611:Dairy Products / Q000009:adverse effects / Q000382:microbiology; D004318:Doxycycline / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D004679:Encephalomyelitis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D005260:Female; D005506:Food Contamination; D006801:Humans; D008800:Mexico; D011129:Polyradiculoneuropathy / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D012293:Rifampin / Q000627:therapeutic use
chemical_list: D000907:Antibodies, Bacterial; D004318:Doxycycline; D012293:Rifampin