Interplay between Ras-related and heterotrimeric GTP binding proteins: lifestyles of the BIG and little.
Directed interactions of heterotrimeric G-proteins coupled to receptors responding to extracellular signals and small Ras-related GTPases that control a variety of intracellular processes are being elucidated by recent work. We explore two of the most well-characterized pathways that couple big G-proteins to their smaller relatives.
Bokoch
G M
GM
Department of Immunology, Scripps Research Institute, La Jolla, California 92037, USA.
D000818:Animals; D019204:GTP-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D018631:ras Proteins
D019204:GTP-Binding Proteins; D018631:ras Proteins