The primary structure of rat ribosomal protein L6.
The amino acid sequence of the rat 60S ribosomal subunit protein L6 was deduced from the sequence of nucleotides in a recombinant cDNA and confirmed by determination of amino acid sequences in the protein. Ribosomal protein L6 has 296 amino acids (the NH2-terminal methionine is removed after translation of mRNA); the molecular weight is 33,417. Hybridization of the cDNA to digests of nuclear DNA suggests that there are 7 to 10 copies of the L6 gene. The mRNA for the protein is about 1,100 nucleotides in length. Rat L6 is related to ribosomal proteins from other eukaryotes and to histone H1.
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Department of Biochemistry and Molecular Biology, University of Chicago, Illinois 60637, USA.
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D000595:Amino Acid Sequence; D000596:Amino Acids / Q000032:analysis; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D017124:Conserved Sequence / Q000235:genetics; D018076:DNA, Complementary / Q000737:chemistry; D016208:Databases, Factual; D018628:Gene Dosage; D008969:Molecular Sequence Data; D008970:Molecular Weight; D016366:Open Reading Frames / Q000235:genetics; D009943:Organophosphorus Compounds / Q000378:metabolism; D010446:Peptide Fragments / Q000737:chemistry; D012333:RNA, Messenger / Q000737:chemistry; D051381:Rats; D012269:Ribosomal Proteins / Q000737:chemistry* / Q000302:isolation & purification; D017421:Sequence Analysis; D012984:Software
C043517:2-(4-isothiocyanatophenoxy)-1,3,2-dioxaphosphinene 2-oxide; D000596:Amino Acids; D018076:DNA, Complementary; D009943:Organophosphorus Compounds; D010446:Peptide Fragments; D012333:RNA, Messenger; D012269:Ribosomal Proteins; C031249:ribosomal protein L6