Primary chemotherapy: how does it compare with surgery?
Small-volume metastatic nonseminoma primary chemotherapy following orchidectomy cures the same high proportion of patients as does retroperitoneal lymph node dissection (RPLND). The 5-year survival in 122 patients treated at the Royal Marsden Hospital was 97%; 35 of these men had postchemotherapy lymphadenectomy and only 5 suffered loss of ejaculation. Primary chemotherapy is a reasonable alternative to RPLND for stage II testicular nonseminoma.
Horwich
A
A
Institute of Cancer Research, Royal Marsden NHS Trust, Sutton, Surrey, United Kingdom.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D018237:Germinoma / Q000188:drug therapy* / Q000601:surgery*; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D009919:Orchiectomy; D013736:Testicular Neoplasms / Q000188:drug therapy* / Q000601:surgery*