title: Syndrome of inappropriate secretion of antidiuretic hormone in elderly patients with rheumatoid arthritis associated with infections: report of two cases.
abstract: Two rheumatoid arthritis (RA) patients with the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) during the course of infection are herein reported. One patient developed SIADH during the course of a localized cutaneous herpes zoster infection while the other developed SIADH in conjunction with Staphylococcus simulans septicemia. We consider that the development of SIADH was strongly associated with superimposed infections in the underlying RA. This is the first report discussing the association of SIADH and infections in RA patients in which SIADH is diagnosed by measurement of plasma ADH.
authors.affiliation: Department of Physical Therapy and Rheumatology, Beppu National Hospital.
authors.forename: E
authors.initials: E
authors.lastname: Furuta
authors.forename: M
authors.initials: M
authors.lastname: Yasuda
authors.forename: K
authors.initials: K
authors.lastname: Yoshioka
authors.forename: T
authors.initials: T
authors.lastname: Isayama
authors.forename: M
authors.initials: M
authors.lastname: Nobunaga
mesh_terms: D000368:Aged; D018501:Antirheumatic Agents / Q000009:adverse effects / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006562:Herpes Zoster / Q000150:complications*; D006801:Humans; D006993:Hypnotics and Sedatives / Q000009:adverse effects / Q000627:therapeutic use; D007010:Hyponatremia / Q000209:etiology; D007177:Inappropriate ADH Syndrome / Q000139:chemically induced / Q000209:etiology*; D018805:Sepsis / Q000150:complications*; D013203:Staphylococcal Infections / Q000150:complications*; D014552:Urinary Tract Infections / Q000150:complications
chemical_list: D018501:Antirheumatic Agents; D006993:Hypnotics and Sedatives