title: Drug-dependent exercise-induced anaphylaxis.
abstract: Exercise-induced anaphylaxis (EIA) is well known and may be food-dependent. We describe a patient with a history of anaphylaxis during exercise after taking nafylpropion acid (Naprosyne), a nonsteroidal anti-inflammatory drug. An exercise-challenge test after Naprosyne intake induced bronchoconstriction. The combination of history and challenge tests suggests that intolerance or allergy to drugs may present as EIA.
authors.affiliation: Department of Allergology, University Hospital Rotterdam, Netherlands.
authors.forename: R G
authors.initials: RG
authors.lastname: van Wijk
authors.forename: H
authors.initials: H
authors.lastname: de Groot
authors.forename: J M
authors.initials: JM
authors.lastname: Bogaard
mesh_terms: D000293:Adolescent; D000707:Anaphylaxis / Q000139:chemically induced / Q000209:etiology*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D015444:Exercise; D005260:Female; D006801:Humans; D009288:Naproxen / Q000009:adverse effects*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D009288:Naproxen