Longitudinal neuropsychological evaluation of HIV-infected intravenous drug users.
The present study aimed to describe the cognitive status of a group of HIV-positive asymptomatic intravenous drug users (IVDU) and changes which occurred over a 12-month follow-up period. Forty-two HIV positive IVDU were selected and matched for age, sex, educational level and pattern of drug abuse with 39 seronegative IVDU controls. Baseline and follow-up evaluation included neuropsychological tests exploring attention, language, memory, logic and visuomotor abilities, biological markers and clinical parameters. About one-third of both seropositive and seronegative subjects showed at baseline slight cognitive deficits, which did not change during the follow-up period.
Bono
G
G
IRCCS C. Mondino, University of Pavia, Italy.
Mauri
M
M
Sinforiani
E
E
Barbarini
G
G
Minoli
L
L
Fea
M
M
D015526:AIDS Dementia Complex / Q000175:diagnosis* / Q000523:psychology; D000328:Adult; D018791:CD4 Lymphocyte Count; D005260:Female; D005500:Follow-Up Studies; D015658:HIV Infections / Q000175:diagnosis / Q000523:psychology / Q000635:transmission*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D011594:Psychometrics; D015819:Substance Abuse, Intravenous / Q000150:complications*