title: Meningiomas of the space of the cavernous sinus.
abstract: During the years 1985 to 1992, we encountered 59 patients with meningiomas involving the space of the cavernous sinus. In 29 of these patients, meningiomas were primarily located within the space of the cavernous sinus and were operated on without mortality and with low morbidity. A small subtemporal surgical approach was favored, which allowed initial tumor resection from the posterior aspect, where the Parkinson's triangle is wide, thus avoiding the additional morbidity of large-scale approaches. According to the relationships of the all-important cranial nerves passing within the lateral wall of the cavernous sinus, we divided the primary intracavernous meningiomas into four types, which reflected not only the preoperative cranial nerve deficit but also the feasibility of surgical resection. Cranial nerve function deteriorated after operations in 14% of oculomotor nerves, in one abducent nerve, in 58% of trochlear nerves, and in 21% of trigeminal nerves. We encountered improvement of function in 43% of oculomotor nerves, in 50% of abducent nerves, and in approximately 30% of the second and third but in only 7% of the first branches of trigeminal nerves. There was no improvement in trochlear nerve function. Improvement of oculomotor nerve function was observed only in moderately impaired nerves, which indicates that surgery should be undertaken early to preserve or improve oculomotor nerve function.
authors.affiliation: Department of Neurosurgery, Donauspital, Vienna, Austria.
authors.forename: E
authors.initials: E
authors.lastname: Knosp
authors.forename: A
authors.initials: A
authors.lastname: Perneczky
authors.forename: W T
authors.initials: WT
authors.lastname: Koos
authors.forename: G
authors.initials: G
authors.lastname: Fries
authors.forename: C
authors.initials: C
authors.lastname: Matula
mesh_terms: D002426:Cavernous Sinus / Q000473:pathology / Q000601:surgery*; D003389:Cranial Nerve Diseases / Q000209:etiology; D020209:Cranial Nerve Injuries; D003390:Cranial Nerve Neoplasms / Q000209:etiology / Q000601:surgery; D003391:Cranial Nerves / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000473:pathology / Q000601:surgery*; D008579:Meningioma / Q000473:pathology / Q000601:surgery*; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D009460:Neurologic Examination; D011183:Postoperative Complications / Q000209:etiology; D013101:Sphenoid Sinus / Q000473:pathology / Q000601:surgery