title: Comparison of magnetic resonance angiography and conventional angiography in sickle cell disease: clinical significance and reliability.
abstract: We retrospectively reviewed the medical records and conventional angiograms of 21 patients with known sickle cell disease, who underwent a total of 50 magnetic resonance imaging (MRI) and magnetic resonance angiography (MRA) studies. MRA and conventional angiography were assessed separately for evidence of stenosis or occlusion. Follow up MRI/MRA studies were also assessed for evidence of progression, regression or stability of the disease in these patients. In the carotid circulation, MRA made the correct diagnosis in 85% of the vessels evaluated with a sensitivity of 80.5% and a specificity of 94%. MRA was also found to show evidence of disease progression, more often than did MRI or the clinical condition of the patients.
authors.affiliation: Department of Radiology, Mansoura University Hospital, Egypt.
authors.forename: A Y
authors.initials: AY
authors.lastname: Kandeel
authors.forename: R A
authors.initials: RA
authors.lastname: Zimmerman
authors.forename: K
authors.initials: K
authors.lastname: Ohene-Frempong
mesh_terms: D000293:Adolescent; D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications*; D001488:Basilar Artery / Q000000981:diagnostic imaging / Q000473:pathology; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000473:pathology; D002533:Cerebral Angiography; D002561:Cerebrovascular Disorders / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014711:Vertebral Artery / Q000000981:diagnostic imaging / Q000473:pathology