title: Carcinoid tumor of the common bile duct producing gastrin and serotonin.
abstract: Carcinoid tumors of the biliary tract are rare. We report a 47 year-old man who was unexpectedly found to have a nonobstructing carcinoid tumor of the common bile duct during orthotopic liver transplantation for decompensated cirrhosis. No metastases were noted. Five months after resection of the common bile duct and liver transplantation, the patient had no evidence of residual tumor. The carcinoid was a sclerotic tumor of insular type and was immunoreactive for gastrin and serotonin, but nonfunctional. We review the literature on carcinoids of the extrahepatic bile duct.
authors.affiliation: Department of Pathology, Yale University, New Haven, Connecticut 06520-8023, USA.
authors.forename: L
authors.initials: L
authors.lastname: Hao
authors.forename: A L
authors.initials: AL
authors.lastname: Friedman
authors.forename: V J
authors.initials: VJ
authors.lastname: Navarro
authors.forename: B
authors.initials: B
authors.lastname: West
authors.forename: M E
authors.initials: ME
authors.lastname: Robert
mesh_terms: D000328:Adult; D002276:Carcinoid Tumor / Q000378:metabolism* / Q000473:pathology / Q000601:surgery; D003135:Common Bile Duct / Q000473:pathology; D003138:Common Bile Duct Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000601:surgery; D005755:Gastrins / Q000378:metabolism*; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic / Q000601:surgery; D016031:Liver Transplantation; D008297:Male; D012701:Serotonin / Q000378:metabolism*
chemical_list: D005755:Gastrins; D012701:Serotonin