Confirmation of early menopause in fragile X carriers.
Fragile X carriers have a median age of menopause 6 to 8 years earlier than women in the general population, with 28% experiencing premature ovarian failure defined as menopause before the age of 40 years. This information was obtained from 203 returned questionnaires from women in the UK Fragile X Society.
Partington
M W
MW
Hunter Genetics, Newcastle, New South Wales, Australia.
Moore
D Y
DY
Turner
G M
GM
D000328:Adult; D000367:Age Factors; D005190:Family; D005260:Female; D005600:Fragile X Syndrome / Q000235:genetics* / Q000503:physiopathology*; D006579:Heterozygote; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D016649:Primary Ovarian Insufficiency / Q000453:epidemiology; D012016:Reference Values; D011795:Surveys and Questionnaires