title: Novel functional polymers: poly(dimethylsiloxane)-polyamide multiblock copolymer. V. The interaction between biomolecules and the surface of aramid-silicone resins.
abstract: Multiblock copolymers consisting of aromatic polyamide(aramid) and poly(dimethylsiloxane) (PDMS) aramid-silicone resins (PASs) were synthesized by low temperature solution polycondensation, and PAS films were prepared by casting from an N,N'-dimethylacetamide solution. In this study, we investigated bovine serum albumin (BSA) adsorption, L929 cell adhesion, and tissue reaction on the surface of PAS in order to clarify the interaction between PAS and biomolecules. It was found that the amount of adsorbed biomolecules on PAS was extremely low in contrast with those on aramid and nylon films, and it was comparable to SILASTIC 500-1 film. This suppression of adsorption of biomolecules onto PAS seemed to be due to the low surface free energy of the outermost surface of PAS, where PDMS block was condensed.
authors.affiliation: Department of Applied Chemistry and Chemical Engineering, Faculty of Engineering, Kagoshima University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Furuzono
authors.forename: A
authors.initials: A
authors.lastname: Kishida
authors.forename: M
authors.initials: M
authors.lastname: Yanagi
authors.forename: T
authors.initials: T
authors.lastname: Matsumoto
authors.forename: T
authors.initials: T
authors.lastname: Kanda
authors.forename: T
authors.initials: T
authors.lastname: Nakamura
authors.forename: T
authors.initials: T
authors.lastname: Aiko
authors.forename: I
authors.initials: I
authors.lastname: Maruyama
authors.forename: M
authors.initials: M
authors.lastname: Akashi
mesh_terms: D000327:Adsorption; D000818:Animals; D001672:Biocompatible Materials; D002417:Cattle; D002448:Cell Adhesion / Q000502:physiology; D003188:Composite Resins / Q000138:chemical synthesis; D004129:Dimethylpolysiloxanes / Q000737:chemistry* / Q000378:metabolism; D009757:Nylons / Q000737:chemistry* / Q000378:metabolism; D019736:Prostheses and Implants; D012710:Serum Albumin, Bovine / Q000378:metabolism; D012825:Silicon; D012828:Silicones / Q000737:chemistry* / Q000378:metabolism
chemical_list: D001672:Biocompatible Materials; D003188:Composite Resins; D004129:Dimethylpolysiloxanes; D009757:Nylons; D012828:Silicones; D012710:Serum Albumin, Bovine; C013830:baysilon; D012825:Silicon