Citalopram in the treatment of alcoholism: a double-blind placebo-controlled study.
The effect of citalopram and placebo in the treatment of alcoholism was studied in a sample of 62 patients with a follow-up period of four months. The results imply that the new 5-HT re-uptake inhibitor citalopram is significantly more effective than placebo in the treatment of alcoholism. The present study indicates that even severe alcoholism may be treated effectively with a generally available psychopharmacological agent.
Tiihonen
J
J
Department of Forensic Psychiatry, University of Kuopio, Finland.
Ryynänen
O P
OP
Kauhanen
J
J
Hakola
H P
HP
Salaspuro
M
M
D000328:Adult; D000437:Alcoholism / Q000188:drug therapy* / Q000517:prevention & control; D000928:Antidepressive Agents / Q000627:therapeutic use*; D015283:Citalopram / Q000627:therapeutic use*; D004311:Double-Blind Method; D005387:Finland; D006801:Humans; D008297:Male; D008875:Middle Aged; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*
D000928:Antidepressive Agents; D015283:Citalopram; D017367:Selective Serotonin Reuptake Inhibitors