title: Assessment of the magnetic field distribution in yellow and red bone marrow by the MAGSUS technique.
abstract: The MAGSUS imaging technique has been shown to provide insights into the distribution of the macroscopic and microscopic static magnetic field without requiring further data processing. Applications of the MAGSUS technique on bone marrow are reported in more detail in this article. Effects of the superposition of water and lipid signals and of considerable transverse relaxation on MAGSUS imaging are demonstrated, and adapted imaging parameters are presented. Examples of applications on marrow with different physiological and pathological compositions and different locations are shown. Appropriate adjustments for a reliable estimation of the trabecular density in peripheral yellow marrow and for an assessment of the field distribution in hemopoietic red marrow are reported. Osteoporotic peripheral marrow with reduced amount of trabecular structures and alterations due to osteodystrophia deformans can be simply revealed by this method. An estimation of the trabecular density can also be performed by MAGSUS in vertebral bodies of hematologically unaffected persons, but the interindividually differing amount of paramagnetic depositions in the marrow (e.g., hemosiderin) must be taken into account.
authors.affiliation: Department of Diagnostic Radiology, University of Tübingen, Germany.
authors.forename: F
authors.initials: F
authors.lastname: Schick
authors.forename: O
authors.initials: O
authors.lastname: Lutz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001853:Bone Marrow / Q000033:anatomy & histology* / Q000473:pathology*; D001842:Bone and Bones / Q000002:abnormalities / Q000473:pathology; D002648:Child; D004574:Electromagnetic Fields; D005260:Female; D006410:Hematopoiesis; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000473:pathology