How to alter the bacterial genome structure.
Bacterial chromosomes, mostly of circular form, have an unique primary structure that are stably maintained. We initiated a systematic study to induce changes of the structure of the Bacillus subtilis chromosome. There are two main goals: (i) to obtain general concepts for possible plasticity of the bacterial genome and (ii) to apply the proposed genome technology to bacteria.
Itaya
M
M
Mitsubishi Kasei Institute of Life Sciences, Tokyo, Japan.
Toda
T
T
Ohshiro
Y
Y
Ogura
M
M
Tanaka
T
T
D001412:Bacillus subtilis / Q000187:drug effects / Q000235:genetics; D002876:Chromosomes, Bacterial / Q000235:genetics*; D004269:DNA, Bacterial / Q000235:genetics; D004352:Drug Resistance, Microbial / Q000235:genetics; D015321:Gene Rearrangement; D016680:Genome, Bacterial; D015394:Molecular Structure; D011995:Recombination, Genetic
D004269:DNA, Bacterial