title: Hepatogenous photosensitization of ruminants by Brachiaria decumbens and panicum dichotomiflorum in the absence of sporidesmin: lithogenic saponins may be responsible.
abstract: As part of a study of plants involved in crystal-associated hepatogenous photosensitization diseases, samples of Brachiaria decumbens and Panicum dichotomiflorum on which cattle and goats had recently been photosensitized were analyzed. The level of saponins associated with these photosensitization outbreaks were determined by GC-MS. Only low levels of Pithomyces chartarum spores were present on the B decumbens, and all isolates obtained failed to produce sporidesmin.
authors.affiliation: Department of Chemistry, University of Waikato, Hamilton, New Zealand.
authors.forename: L P
authors.initials: LP
authors.lastname: Meagher
authors.forename: A L
authors.initials: AL
authors.lastname: Wilkins
authors.forename: C O
authors.initials: CO
authors.lastname: Miles
authors.forename: R G
authors.initials: RG
authors.lastname: Collin
authors.forename: J J
authors.initials: JJ
authors.lastname: Fagliari
mesh_terms: D000818:Animals; D002417:Cattle; D008401:Gas Chromatography-Mass Spectrometry; D008099:Liver / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D010787:Photosensitivity Disorders / Q000473:pathology*; D010947:Plants, Toxic; D012015:Reference Standards; D012503:Saponins / Q000032:analysis / Q000378:metabolism*; D013173:Sporidesmins / Q000378:metabolism / Q000633:toxicity*
chemical_list: D012503:Saponins; D013173:Sporidesmins