title: [A study of relation between pulmonary function and bronchial hypersensitivity in severe asthmatic children].
abstract: We studied 198 acetylcholine inhalation tests in 31 subjects and 260 exercise loading tests in 43 subjects, who were severe asthmatic children received institutional therapy. Respiratory threshold to acetylcholine (RT-Ach) were significantly lower when %V50 or %MMF were less than 60%. %V50 were significantly lower when EIB (maximum %fall in FEV1.0 after exercise) were more than 15%. These results suggest that in bronchial hypersensitivity tests, %V50 and %MMF which are indexes of peripheral airway obstruction should be examined.
authors.affiliation: Department of Pediatrics, National Higashi Saitama Hospital.
authors.forename: S
authors.initials: S
authors.lastname: Matsuda
authors.forename: H
authors.initials: H
authors.lastname: Sugimoto
authors.forename: Y
authors.initials: Y
authors.lastname: Iikura
mesh_terms: D000109:Acetylcholine; D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000503:physiopathology*; D016535:Bronchial Hyperreactivity / Q000503:physiopathology*; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D012129:Respiratory Function Tests
chemical_list: D000109:Acetylcholine