Two classes of olfactory receptors in Xenopus laevis.
Xenopus laevis possess a gene repertoire encoding two distinct classes of olfactory receptors: one class related to receptors of fish and one class similar to receptors of mammals. Sequence comparison indicates that the fish-like receptors represent closely related members of only two subfamilies, whereas mammalian-like receptors are more distantly related, most of them representing a different subfamily. The fish-like receptor genes are exclusively expressed in the lateral diverticulum of the frog's nose, specialized for detecting water-soluble odorants, whereas mammalian-like receptors are expressed in sensory neurons of the main diverticulum, responsible for the reception of volatile odors.
Freitag
J
J
University Stuttgart-Hohenheim, Institute of Zoophysiology, Stuttgart, Federal Republic of Germany.
Krieger
J
J
Strotmann
J
J
Breer
H
H
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D005399:Fishes / Q000502:physiology; D008322:Mammals / Q000502:physiology; D015335:Molecular Probes / Q000235:genetics; D008969:Molecular Sequence Data; D009296:Nasal Cavity / Q000294:innervation; D009833:Olfactory Pathways / Q000502:physiology*; D010802:Phylogeny; D011984:Sensory Receptor Cells / Q000502:physiology*; D017386:Sequence Homology, Amino Acid; D014982:Xenopus laevis / Q000235:genetics / Q000502:physiology*
D015335:Molecular Probes