title: The efficacy of soft contact lens disinfection solutions against Serratia marcescens and Pseudomonas aeruginosa.
abstract: Samples of five different solutions for disinfection of soft contact lenses were experimentally inoculated with a strain of Pseudomonas aeruginosa or Serratia marcescens. No bacteria could be detected after one hour in solutions with biguanids, while they survived in reduced number up to 72 h in solutions with polyquaternium as active substance. However, prolonged survival after one week could not be detected. Lenses treated with polyquaternium based contact lens disinfectant solutions overnight may still harbour bacteria, which might increase the risk for bacterial complications, such as keratitis.
authors.affiliation: Department of Immunology, Microbiology, Pathology and Infectious Diseases, Karolinska Institute, Huddinge Hospital, Sweden.
authors.forename: P A
authors.initials: PA
authors.lastname: Parment
authors.forename: B
authors.initials: B
authors.lastname: Colucci
authors.forename: B
authors.initials: B
authors.lastname: Nyström
mesh_terms: D015169:Colony Count, Microbial; D018639:Contact Lens Solutions / Q000494:pharmacology*; D003263:Contact Lenses, Hydrophilic; D009883:Ophthalmic Solutions; D011550:Pseudomonas aeruginosa / Q000187:drug effects* / Q000502:physiology; D012706:Serratia marcescens / Q000187:drug effects* / Q000502:physiology
chemical_list: D018639:Contact Lens Solutions; D009883:Ophthalmic Solutions