Adenovirus mixture isolated from the brain of an AIDS patient with encephalitis.
A mixture of adenoviruses 31 and 49 was isolated from the brain of an AIDS patient with encephalitis. Adenovirus hexon protein was detected in neurons by indirect immunofluorescence. By restriction endonuclease analysis both adenovirus 31 and 49 were shown to be new genotypes. This is the first report of the isolation of a mixture of adenoviruses from adenovirus encephalitis and the first association of adenovirus 49, a new candidate serotype, with encephalitis.
Schnurr
D
D
Viral and Rickettsial Disease Laboratory, California State Department of Health Services, Berkeley 94704, USA.
Bollen
A
A
Crawford-Miksza
L
L
Dondero
M E
ME
Yagi
S
S
D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000821:virology*; D000258:Adenovirus Infections, Human / Q000150:complications / Q000821:virology*; D000260:Adenoviruses, Human / Q000145:classification / Q000302:isolation & purification*; D000956:Antigens, Viral / Q000276:immunology; D001921:Brain / Q000473:pathology / Q000821:virology; D002213:Capsid / Q000276:immunology; D036022:Capsid Proteins; D002460:Cell Line; D018792:Encephalitis, Viral / Q000150:complications / Q000821:virology*; D017809:Fatal Outcome; D005260:Female; D005838:Genotype; D006801:Humans; D008875:Middle Aged; D012703:Serotyping; D014407:Tumor Cells, Cultured
D000956:Antigens, Viral; D036022:Capsid Proteins; C018315:hexon capsid protein, Adenovirus