title: Interleukin-2 receptor signaling mechanisms.
authors.affiliation: Department of Immunology, Mayo Clinic, Rochester, Minnesota 55905, USA.
authors.forename: L M
authors.initials: LM
authors.lastname: Karnitz
authors.forename: R T
authors.initials: RT
authors.lastname: Abraham
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D017871:Calcium-Calmodulin-Dependent Protein Kinases / Q000276:immunology; D002352:Carrier Proteins / Q000276:immunology; D004268:DNA-Binding Proteins / Q000276:immunology; D016193:G1 Phase; D006360:Heat-Shock Proteins / Q000276:immunology; D006801:Humans; D007376:Interleukin-2 / Q000276:immunology; D053613:Janus Kinase 1; D053614:Janus Kinase 2; D053616:Janus Kinase 3; D008969:Molecular Sequence Data; D019869:Phosphatidylinositol 3-Kinases; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000276:immunology; D011090:Polyenes / Q000276:immunology; D011505:Protein-Tyrosine Kinases / Q000276:immunology; D011518:Proto-Oncogene Proteins; D015375:Receptors, Interleukin-2 / Q000276:immunology*; D050795:STAT2 Transcription Factor; D050796:STAT3 Transcription Factor; D050797:STAT4 Transcription Factor; D015398:Signal Transduction / Q000276:immunology*; D020123:Sirolimus; D013601:T-Lymphocytes / Q000276:immunology*; D022021:Tacrolimus Binding Proteins; D015534:Trans-Activators / Q000276:immunology; D018631:ras Proteins / Q000276:immunology
chemical_list: D002352:Carrier Proteins; D004268:DNA-Binding Proteins; D006360:Heat-Shock Proteins; D007376:Interleukin-2; D011090:Polyenes; D011518:Proto-Oncogene Proteins; D015375:Receptors, Interleukin-2; D050795:STAT2 Transcription Factor; D050796:STAT3 Transcription Factor; C494086:STAT3 protein, human; D050797:STAT4 Transcription Factor; C494090:STAT4 protein, human; D015534:Trans-Activators; D019869:Phosphatidylinositol 3-Kinases; D017853:Phosphotransferases (Alcohol Group Acceptor); D011505:Protein-Tyrosine Kinases; C507904:JAK1 protein, human; C507924:JAK2 protein, human; C507933:JAK3 protein, human; D053613:Janus Kinase 1; D053614:Janus Kinase 2; D053616:Janus Kinase 3; D017871:Calcium-Calmodulin-Dependent Protein Kinases; D018631:ras Proteins; D022021:Tacrolimus Binding Proteins; D020123:Sirolimus