title: Factors associated with tuberculosis at AIDS diagnosis in France.
abstract: OBJECTIVE
  To identify factors associated with tuberculosis (TB) at AIDS diagnosis in France.
  
  
  METHODS
  Analysis of surveillance data.
  
  
  METHODS
  Among all adult AIDS cases diagnosed since January 1988 and reported by December 1993 in France, the proportion diagnosed with AIDS-defining TB (extrapulmonary TB among cases diagnosed between 1988 and 1992, all forms of TB among cases diagnosed in 1993) was analysed by year of diagnosis, sex, age, nationality, profession, HIV transmission group and region of residence by multiple logistic regression.
  
  
  RESULTS
  Between 1988 and 1992, 5.7% (1134 out of 19,968) of AIDS patients were diagnosed with AIDS-defining extrapulmonary TB. Presence of extrapulmonary TB was associated with male sex [adjusted odds ratio (AOR), 1.7], nationality from a sub-Saharan country (AOR, 4.8), heterosexual contact or injecting drug use (AOR, 2.4 and 2.7, respectively), residence in the Paris area (AOR, 1.7), and unemployment or factory work (AOR, 2.5 and 2.4, respectively). In 1993, 10.6% (393 out of 3721) of AIDS patients were diagnosed with TB (all forms). In multivariate analysis, three factors were independently associated with the risk of presenting TB at AIDS diagnosis: transmission category, nationality, and region of residence.
  
  
  CONCLUSIONS
  Some factors associated with TB at AIDS diagnosis in France are known to be related to a high incidence of TB in industrialized countries (nationality, from a developing country, male sex, low socioeconomic status). The independent association with injecting drug use or residence in Paris suggests a contribution of recent TB infection in specific groups of HIV-infected persons. This contribution should be evaluated to implement appropriate preventive measures.
authors.affiliation: National Public Health Centre, France.
authors.forename: I
authors.initials: I
authors.lastname: Triol
authors.forename: V
authors.initials: V
authors.lastname: Schwoebel
authors.forename: M C
authors.initials: MC
authors.lastname: Delmas
authors.forename: R
authors.initials: R
authors.lastname: Pinget
authors.forename: A
authors.initials: A
authors.lastname: Laporte
authors.forename: J B
authors.initials: JB
authors.lastname: Brunet
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology*; D000163:Acquired Immunodeficiency Syndrome / Q000175:diagnosis / Q000635:transmission; D000328:Adult; D000367:Age Factors; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D012307:Risk Factors; D012737:Sex Factors; D014376:Tuberculosis / Q000453:epidemiology; D014397:Tuberculosis, Pulmonary / Q000453:epidemiology*