title: Tics status.
abstract: OBJECTIVE
  To describe two patients with tics status, propose a definition of this syndrome and draw attention to its clinical significance.
  
  
  METHODS
  Two patients suffering from Tourette's Syndrome who had developed episodes of continual motor tics that lasted from minutes to hours, were non-suppressible and intruded into normal functioning, were treated with an increase in the dose of haloperidol, in one case with the addition of clonazepam.
  
  
  RESULTS
  The offset of the episodes was gradual and the tic disorder was worse after the episodes. One patient had further spontaneous episodes of tics status.
  
  
  CONCLUSIONS
  The recognition of tics status has implications for the management as well as our understanding of the pathobiology of tics and Tourette's Syndrome. The definition of tics status should be standardised.
authors.affiliation: School of Psychiatry, University of New South Wales, Sydney, Australia.
authors.forename: P
authors.initials: P
authors.lastname: Sachdev
authors.forename: K Y
authors.initials: KY
authors.lastname: Chee
authors.forename: A
authors.initials: A
authors.lastname: Wilson
mesh_terms: D000293:Adolescent; D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000009:adverse effects; D003024:Clozapine / Q000008:administration & dosage / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D006220:Haloperidol / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D009460:Neurologic Examination / Q000187:drug effects; D012008:Recurrence; D013981:Tic Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology; D005879:Tourette Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000523:psychology
chemical_list: D014150:Antipsychotic Agents; D003024:Clozapine; D006220:Haloperidol