A two-component response regulator, gltR, is required for glucose transport activity in Pseudomonas aeruginosa PAO1.
A 729-bp open reading frame (gltR) was identified in Pseudomonas aeruginosa PAO1 that encodes a product homologous to the two-component response regulator family of proteins. Disruption of gltR caused loss of glucose transport activity. Restoration of gltR resulted in wild-type levels of glucose transport. These findings indicate that gltR is required for expression of the glucose transport system in P. aeruginosa.
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Department of Microbiology and Immunology, East Carolina University School of Medicine, Greenville, North Carolina 27858-4354, USA.
Proctor
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PV
D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics*; D001692:Biological Transport; D015964:Gene Expression Regulation, Bacterial; D005947:Glucose / Q000378:metabolism*; D008969:Molecular Sequence Data; D009004:Monosaccharide Transport Proteins; D016254:Mutagenesis, Insertional; D011550:Pseudomonas aeruginosa / Q000235:genetics* / Q000378:metabolism; D017386:Sequence Homology, Amino Acid
D001426:Bacterial Proteins; C101962:GltR protein, Pseudomonas aeruginosa; D009004:Monosaccharide Transport Proteins; D005947:Glucose