Neuronal migration disorder presenting with epilepsy: a report of five illustrative cases.
Neuronal migration disorders are an uncommon but well-recognised cause of medically intractable epilepsy. The increasing availability of magnetic resonance imaging of the brain has made it possible to diagnose this condition ante-mortem. There are several types of migration disorders, each with different radiological and clinical features. A case each of focal cortical dysplasia, focal subcortical heterotopia, double cortex syndrome, periventricular nodular heterotopia and closed lip schizencephaly is presented to highlight the distinctive features of each entity.
Chee
M W
MW
Department of Neurology, Singapore General Hospital.
Chee
T S
TS
Hui
F
F
D000328:Adult; D001921:Brain / Q000002:abnormalities* / Q000473:pathology; D001927:Brain Diseases / Q000150:complications* / Q000175:diagnosis; D002465:Cell Movement; D002540:Cerebral Cortex / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D002828:Choristoma / Q000150:complications / Q000175:diagnosis; D004828:Epilepsies, Partial / Q000209:etiology; D004827:Epilepsy / Q000175:diagnosis / Q000209:etiology*; D004833:Epilepsy, Temporal Lobe / Q000209:etiology; D004830:Epilepsy, Tonic-Clonic / Q000209:etiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009474:Neurons / Q000473:pathology; D009778:Occipital Lobe / Q000473:pathology; D012688:Septum Pellucidum / Q000002:abnormalities; D013702:Temporal Lobe / Q000473:pathology