Cardiac rhabdomyoma of a neonate: an autopsy case report.
A primigravida delivered a cyanosed female infant with a very low Apgar score. Cardiac anomaly of the fetus was detected at 32 weeks of gestation by ultrasonography. The baby died on the day of delivery. Autopsy revealed multiple tumor masses in the interventricular septum and ventricular walls. The tumor originating from the interventricular septum was the largest and measured 3.7 x 3 cm. Histologically, the tumor was composed of large polygonal glycogen-laden cells and 'spider-cells'. Eosinophilic giant histiocytic cells were also observed in the spleen. Ultrastructural features of the tumor cells correlated with those of typical cardiac muscle cells.
Sadi
A M
AM
Department of Clinical Laboratory Medicine, University of the Ryukyus, Okinawa, Japan.
Toda
T
T
Kiyuna
M
M
Tamamoto
T
T
Kina
K
K
Hirayasu
K
K
Yara
A
A
D017809:Fatal Outcome; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D006338:Heart Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D009206:Myocardium / Q000473:pathology / Q000648:ultrastructure; D011247:Pregnancy; D012207:Rhabdomyoma / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D016216:Ultrasonography, Prenatal