title: Cyclic alterations in rhesus monkey endometrium by scanning electron microscopy.
abstract: The present study was undertaken to correlate the surface topography of endometrium with altered concentrations of circulating steroids during different phases of the artificially-induced menstrual cycle. Scanning electron microscopy demonstrated that oestradiol during the oestrogenic phase induces an increase in the number of ciliated cells and the size of microvilli; by contrast, progesterone, in addition to inducing secretory activity in non-ciliated cells, had a negative effect on oestradiol-dependent morphological characteristics of ciliated cells, causing a reduction in cell number and deciliation, and inducing drooping of cilia during the progestogenic phase of the artificially-induced menstrual cycle. In addition, surface and glandular epithelial cells both actively participate in restoration of the endometrial surface during the menstrual phase, an event which parallels endometrial shedding.
authors.affiliation: Electron Microscopy Section, Central Drug Research Institute, Chattar Manzil Palace, Lucknow, India.
authors.forename: D
authors.initials: D
authors.lastname: Bhartiya
authors.forename: V K
authors.initials: VK
authors.lastname: Bajpai
mesh_terms: D000818:Animals; D002923:Cilia / Q000648:ultrastructure; D004717:Endometrium / Q000648:ultrastructure*; D004848:Epithelium / Q000648:ultrastructure; D004958:Estradiol / Q000097:blood / Q000494:pharmacology; D005260:Female; D008253:Macaca mulatta; D008597:Menstrual Cycle; D008855:Microscopy, Electron, Scanning; D008871:Microvilli / Q000648:ultrastructure; D011374:Progesterone / Q000097:blood / Q000494:pharmacology
chemical_list: D011374:Progesterone; D004958:Estradiol