title: In utero endoscopic devascularization of a large chorioangioma.
abstract: Clinically significant chorioangiomas, i.e. those greater than 4 cm in diameter, are associated with an overall fetal loss rate of approximately 40%. Maternal complications may also be present. Most patients diagnosed with chorioangiomas have been managed expectantly. A patient with a large chorioangioma was referred to our institution, with a fetus that was hydropic and showed sonographic signs of over heart failure. Fetal anemia, marked erythropoiesis and hypoalbuminemia were documented on cordocentesis. The blood supply to the mass consisted of an artery and a vein of 9 mm in diameter. The vascular supply to the tumor was ablated via operative fetoscopy by suture ligation of the arterial supply, after subchorionic dissection of the vessel. The remaining blood supply was electrocoagulated with bipolar cautery. Although the procedure was technically successful, the fetus died on the 3rd postoperative day. This case illustrates ablation of the blood supply of placental chorioangiomas as a potential management alternative for those patients with large chorioangiomas. Early identification and treatment may result in a successful outcome.
authors.affiliation: Department of Obstetrics and Gynecology, Hutzel Hospital/Wayne State University, Detroit, MI, USA.
authors.forename: R A
authors.initials: RA
authors.lastname: Quintero
authors.forename: H
authors.initials: H
authors.lastname: Reich
authors.forename: R
authors.initials: R
authors.lastname: Romero
authors.forename: M P
authors.initials: MP
authors.lastname: Johnson
authors.forename: L
authors.initials: L
authors.lastname: Gonçalves
authors.forename: M I
authors.initials: MI
authors.lastname: Evans
mesh_terms: D004724:Endoscopy / Q000379:methods; D005260:Female; D005313:Fetal Death; D005332:Fetoscopy; D005865:Gestational Age; D006391:Hemangioma / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D010920:Placenta / Q000473:pathology*; D010922:Placenta Diseases / Q000000981:diagnostic imaging / Q000601:surgery*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000000981:diagnostic imaging / Q000601:surgery*; D011256:Pregnancy Outcome; D016216:Ultrasonography, Prenatal