title: Renal transplantation in cats with chronic renal failure.
abstract: Renal transplantation was performed on 6 cats with chronic renal failure. Clinical signs and the blood chemistry findings (BUN, Cr, IP) improved one week after renal transplantation. Renal anemia also improved 3-4 weeks after surgery. Two cases had the same complications, hydronephrosis and hydroureter within 1 or 2 weeks of surgery, evidenced by marked elevations of BUN and Cr, suggesting that ureteral obstruction at the site of ureterocystostomy is the main complication of renal transplantation in cats. As a new resolution for this problem, we transplanted the ureter with the intact ureteral opening of the bladder from the donor in the remaining 4 cats. Ureteral obstruction was not observed in them, thus the procedure was considered to be useful for avoiding this complication. Two cats died of pneumonia and other complications within 3 months. There were no acute rejections or side effects from the immunosuppressant during the observation period in the remaining four cats.
authors.affiliation: Department of Surgery, School of Veterinary Medicine, Azabu University, Kanagawa, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Mishina
authors.forename: T
authors.initials: T
authors.lastname: Watanabe
authors.forename: H
authors.initials: H
authors.lastname: Maeda
authors.forename: K
authors.initials: K
authors.lastname: Fujii
authors.forename: Y
authors.initials: Y
authors.lastname: Wakao
authors.forename: M
authors.initials: M
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Ejima
mesh_terms: D000818:Animals; D001806:Blood Urea Nitrogen; D002371:Cat Diseases; D002415:Cats; D003404:Creatinine / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D007165:Immunosuppression Therapy / Q000662:veterinary; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007676:Kidney Failure, Chronic / Q000601:surgery / Q000662:veterinary*; D016030:Kidney Transplantation / Q000379:methods / Q000502:physiology / Q000662:veterinary*; D008297:Male
chemical_list: D007166:Immunosuppressive Agents; D003404:Creatinine