title: [Indications for transplant nephrectomy with reference to possible complications].
abstract: Mortality rates of 1.2-38% and morbidity rates up to 68% following transplant nephrectomy (TPL-X) have been reported in the literature. From 1988 to 1995, 40 TPL-X were performed in the transplant centre in Bremen. In 15 cases the organs were removed within the first 6 weeks after renal transplantation. The indications were infarction in 10 cases, hyperacute/acute rejection in 3 cases, and repeated rejections with irreversible functional disorder in 2 cases. In the 25 patients in whom TPL-X was performed later than 6 weeks after transplantation the indication was chronic rejection associated with clinical findings in every case. The overall mortality rate was zero in the first 6 weeks after TPL-X, and the morbidity rate, 20%. TPL-X is a re-operation in patients with chronic disease. From this point of view the complication rate with a subtle technique is acceptable. The indications for TPL-X have not been well defined in the literature, so that the decision as to whether or not TPL-X is indicated is made on the basis of the individual situation. TPL-X seems not to be necessary in all cases of transplant failure.
authors.affiliation: Urologische Klinik, Zentralkrankenhaus St.-Jürgen-Strasse, Bremen.
authors.forename: W
authors.initials: W
authors.lastname: Höppner
authors.forename: K
authors.initials: K
authors.lastname: Dreikorn
mesh_terms: D000328:Adult; D002423:Cause of Death; D005260:Female; D005500:Follow-Up Studies; D006084:Graft Rejection / Q000401:mortality / Q000601:surgery; D006801:Humans; D007238:Infarction / Q000401:mortality / Q000601:surgery; D007668:Kidney / Q000098:blood supply; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy; D011183:Postoperative Complications / Q000401:mortality / Q000601:surgery*; D012086:Reoperation; D015996:Survival Rate