Lack of association of schizophrenia with the neurotrophin-3 gene locus.
A case-control association study was conducted among patients with schizophrenia (DSM-III-R, n = 141) and unaffected controls (n = 177) of Caucasain and African-American ethnicity. No significant differences in the distribution of a dinucleotide repeat polymorphism in the neurotrophin-3 (NT-3) gene were noted between the two groups. This study does not support an association between schizophrenia and the NT-3 gene locus in a United States cohort.
Nimgaonkar
V L
VL
Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pennsylvania, USA.
Zhang
X R
XR
Brar
J S
JS
DeLeo
M
M
Ganguli
R
R
D000328:Adult; D017668:Age of Onset; D000483:Alleles; D016022:Case-Control Studies; D015331:Cohort Studies; D005260:Female; D016678:Genome; D006801:Humans; D008297:Male; D008875:Middle Aged; D009414:Nerve Growth Factors; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics*; D012559:Schizophrenia / Q000175:diagnosis / Q000235:genetics*
D009414:Nerve Growth Factors