title: [A case resectable hepatic metastases of breast cancer following intrahepatic arterial chemotherapy].
abstract: A 38-year-old woman who had undergone Patey's operation for left breast cancer in July 1990 was admitted in December 1992 for hepatic metastases. Due to bone metastasis (Th10), oophorectomy and hepatic arterial cannulation were performed. Hepatic arterial chemotherapy and oral chemoendocrine therapy yielded a partial response for liver and unclear metastasis of the bone. She had arterial and oral administration after a hepatectomy in October 1994. The patient has had no recurrent signs now (July 1996). We experienced 522 patients with breast carcinoma and 14 cases (2.7%) of all having hepatic metastases. Hepatic arterial chemotherapy was done in three patients. Although one of them had a complete response, she died after 35 months because of bone, brain and liver metastases. Another case was underwent hepatectomy after arterial chemotherapy, but recurrent liver and bone tumors soon appeared. The mean survival period of 15 hepatic metastases, including the case under study here was 9 months, and the one-year survival rate was 23.4%.
authors.affiliation: Dept. of Surgery, Tokyo Metropolitan Fuchu Hospital.
authors.forename: J
authors.initials: J
authors.lastname: Matsumoto
authors.forename: T
authors.initials: T
authors.lastname: Minami
authors.forename: M
authors.initials: M
authors.lastname: Takami
authors.forename: K
authors.initials: K
authors.lastname: Takanishi
authors.forename: T
authors.initials: T
authors.lastname: Matsumine
mesh_terms: D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000556:secondary; D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology*; D005260:Female; D005467:Floxuridine / Q000008:administration & dosage; D006499:Hepatic Artery; D006801:Humans; D015918:Infusion Pumps, Implantable; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000556:secondary*; D008207:Lymphatic Metastasis; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D015996:Survival Rate; D013629:Tamoxifen / Q000008:administration & dosage
chemical_list: D005467:Floxuridine; D013629:Tamoxifen; D016685:Mitomycin; C025034:doxifluridine