Identification of nekoflavin as 7 alpha-hydroxyriboflavin.
Nekoflavin, which was found in cat's choroids [Matsui, K. (1965) J. Biochem. 57, 201-206], was identified as 7 alpha-hydroxyriboflavin by comparing the physicochemical properties of nekoflavin acetate with those of chemically synthesized 7 alpha-hydroxyriboflavin pentaacetate. 7 alpha-Hydroxyriboflavin was synthesized from 4-chloro-2-methylbenzonitrile through 7-cyano-7-demethylriboflavin and 7 alpha-aminoriboflavin, which are also new flavins.
Matsui
K
K
Department of Home Economics, Osaka International University for Women.
Kasai
S
S
D000818:Animals; D002415:Cats; D002829:Choroid / Q000737:chemistry; D002854:Chromatography, Paper; D002855:Chromatography, Thin Layer; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D012256:Riboflavin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet
C101241:nekoflavin pentaacetate; C038138:7-hydroxymethylriboflavin; D012256:Riboflavin