[The evaluation of the mechanism of thrombocytopoiesis from the viewpoint of the phenomenon of emperipolesis].
Cytolytic aggressiveness of bone marrow leucocytes towards megakaryocytes was documented with the aid of a phase contrast Zeitraffer microfilming of alive cells technique. The difference was found between the process above and cell interaction through emperipolesis. The author comes to the conclusion that leucocytes play an active part in platelet production regulation. The data obtained enable new pathognomic methods of treatment to be developed and preventive measures to be devised against blood platelet cytosis involved in the morbid course of quite a number of medical conditions, and further studies to be made.
Mikhaĭlovskaia
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D000818:Animals; D001792:Blood Platelets / Q000166:cytology* / Q000528:radiation effects; D001853:Bone Marrow / Q000528:radiation effects; D001854:Bone Marrow Cells; D003584:Cytological Techniques; D003593:Cytoplasm / Q000528:radiation effects / Q000648:ultrastructure; D006410:Hematopoiesis / Q000528:radiation effects; D007958:Leukocyte Count / Q000528:radiation effects; D007962:Leukocytes / Q000166:cytology / Q000528:radiation effects; D008533:Megakaryocytes / Q000166:cytology / Q000528:radiation effects; D009040:Motion Pictures