title: Two case reports of neurological disease in coal mine preparation plant workers.
abstract: Of 60 cases of neurotoxicity related to occupational exposures of workers at plants producing acrylamide monomers, cases involving neurotoxicity related to jobs using polymers with acrylamide monomer contamination have not been widely reported. In 1992, two patients were referred to the Division of Occupational and Environmental Health, Department of Family and Community Health, Marshall University School of Medicine, in Huntington, West Virginia for evaluation. The patients had worked in different coal preparation plants in southern West Virginia for over 10 years and had exposure to an acrylamide polymer flocculent contaminated with acrylamide monomer. Both patients had no instruction on proper use of, or the dangers of, acrylamide and were not given adequate safety equipment. Patient A developed Parkinsonism and Patient B peripheral neuropathies with a neurogenic bladder. These two case reports highlight the need to reemphasize the basic tenets of occupational health and safety. Many chemicals are being introduced into mining operations and awareness of potential toxic exposures and new diseases not previously reported in the mining industry must become part of the surveillance system by mine management and labor safety committees. Further studies on the extent of acrylamide neurotoxicity in the mining industry is encouraged.
authors.affiliation: Department of Family and Community Health, Marshall University School of Medicine, Huntington, WV, USA.
authors.forename: K B
authors.initials: KB
authors.lastname: Mulloy
mesh_terms: D000178:Acrylamides / Q000009:adverse effects*; D003032:Coal Mining; D005427:Flocculation; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced*; D016273:Occupational Exposure; D016272:Occupational Health; D010302:Parkinson Disease, Secondary / Q000139:chemically induced*; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced*; D011159:Population Surveillance; D012449:Safety; D001750:Urinary Bladder, Neurogenic / Q000139:chemically induced*; D014903:West Virginia
chemical_list: D000178:Acrylamides