title: [Successful UFT-E granule and 5-FUCDDP combination therapy for an unresectable advanced gastric cancer complicated with liver metastasis].
abstract: A 79-year-old man having advanced gastric cancer with liver metastasis was treated by gastric dissection and gastro-jejunostomy. At this time CDDP was injected intraperitoneally at the dose of 30 mg/m2. After operation UFT-E granule was administered orally at the dose of 400 mg/body every day. Two months later he was treated with 5-FU 500 mg/m2 and CDDP 20 mg/m2 intravenously for 3 days. After this treatment, the liver metastatic lesion disappeared and the primary gastric lesion was reduced on CT scan. The same FP chemotherapy was done eight months later. The patient has now survived for more than 1 year and 2 months with a good quality of life by home parenteral nutrition. This UFT-E granule and FP combination therapy seemed to be effective for advanced gastric cancer with liver metastasis.
authors.affiliation: Dept. of Surgery, Tama Metropolitan Geriatric Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Kushibiki
authors.forename: M
authors.initials: M
authors.lastname: Shimada
authors.forename: H
authors.initials: H
authors.lastname: Matsuoka
authors.forename: Y
authors.initials: Y
authors.lastname: Hyakuna
authors.forename: H
authors.initials: H
authors.lastname: Yokomichi
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004338:Drug Combinations; D005743:Gastrectomy; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D016331:Parenteral Nutrition, Home; D011788:Quality of Life; D013274:Stomach Neoplasms / Q000188:drug therapy*; D005641:Tegafur / Q000008:administration & dosage; D014498:Uracil / Q000008:administration & dosage
chemical_list: D004338:Drug Combinations; C096910:UFT(R) drug; D005641:Tegafur; D014498:Uracil; D002945:Cisplatin