title: [Minimally invasive treatment of stress urinary incontinence by collagen administration. Comparison between endosonography controlled and transurethral submucous collagen injection].
abstract: For many years, injectable substances have been in use for the treatment of incontinence. We examined different methods of injecting glutaraldehyde cross-linked bovine collagen injection for their effectiveness in treatment of genuine stress incontinence. In the first group of patients collagen injection was done under endo-ultrasound guidance. In the second group an endoscopic system was used. There was no major difference in patient selection for the two groups. Incontinence symptoms became less severe in only 5 of 15 (33%) patients in the endo-ultrasound group, who then had moderate stress incontinence. Endoscopic collagen treatment resulted in social continence in 15 of the 22 (68.2%) patients. We conclude that endoscopic collagen is superior to endo-ultrasound-guided collagen injection in the treatment of incontinence.
authors.affiliation: Urologische Universitätsklinik Ulm.
authors.forename: H W
authors.initials: HW
authors.lastname: Gottfried
authors.forename: S
authors.initials: S
authors.lastname: Maier
authors.forename: J
authors.initials: J
authors.lastname: Gschwend
authors.forename: E
authors.initials: E
authors.lastname: Brändle
authors.forename: R E
authors.initials: RE
authors.lastname: Hautmann
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D002417:Cattle; D003094:Collagen / Q000008:administration & dosage*; D003558:Cystoscopy; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional; D014550:Urinary Incontinence, Stress / Q000000981:diagnostic imaging / Q000628:therapy*; D016741:Urinary Sphincter, Artificial
chemical_list: D003094:Collagen