title: An infant with severe leucocyte adhesion deficiency.
abstract: A case of severe leucocyte adhesion deficiency occurred in a 6 1/2-month-old boy whose parents were first-degree cousins. Evidence of the disease first became apparent with the late separation of the umbilical cord on the 20th day and with the later development of omphalitis. The most specific finding was the very low levels of CD18 and CD11, 0.44 and 0.15%, respectively. The boy died from sepsis which occurred as an extension of necrotic lesions on the ear and in the gluteal area.
authors.affiliation: Division of Paediatric Allergy and Immunology, Medical Faculty of Cukurova University, Adana, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Güneşer
authors.forename: D U
authors.initials: DU
authors.lastname: Altintaş
authors.forename: P
authors.initials: P
authors.lastname: Aksungur
authors.forename: O
authors.initials: O
authors.lastname: Hergüner
authors.forename: O
authors.initials: O
authors.lastname: Sanal
mesh_terms: D000038:Abscess / Q000276:immunology; D018845:CD11 Antigens / Q000032:analysis; D018821:CD18 Antigens / Q000032:analysis; D017809:Fatal Outcome; D006801:Humans; D007223:Infant; D018370:Leukocyte-Adhesion Deficiency Syndrome / Q000276:immunology / Q000473:pathology; D008297:Male; D009336:Necrosis; D018461:Soft Tissue Infections / Q000276:immunology; D014945:Wound Healing
chemical_list: D018845:CD11 Antigens; D018821:CD18 Antigens