Chromosomal aberration analysis in 85 control individuals.
Chromosomal aberrations (CA) were studied in the peripheral blood lymphocytes of 85 healthy male volunteers from Barcelona (Catalonia, Spain). The effect that factors such as age, life style, work exposure and medical treatment had on the cytological endpoints was studied by means of a Poisson regression model. The results obtained indicate a significant positive relationship between the age of the subjects analyzed and the total of chromosome-type aberrations. With respect to the other variables analyzed, a positive association was found between the frequent consumption of analgesics and the incidence of chromatid-type aberrations.
Carbonell
E
E
Departament de Genètica i de Microbiologia, Edifici Cn, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Peris
F
F
Xamena
N
N
Creus
A
A
Marcos
R
R
D000328:Adult; D000367:Age Factors; D002869:Chromosome Aberrations; D006801:Humans; D008214:Lymphocytes; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D013030:Spain