title: Plasma Lp(a) and t-PA-PAI-1 complex levels in coronary heart disease.
abstract: In this study we investigated serum Lp(a) and plasma t-PA-PAI-1 complex levels in patients with coronary heart disease (CHD). Serum total cholesterol, triglyceride, LDL and VDL cholesterol levels (p < 0.001) and HDL cholesterol levels (p < 0.01) in patients group were found to be significantly different from those in control group. The mean Lp(a) and t-PA-PAI-1 complex levels in patients with coronary heart disease were significantly higher as compared to control group (p < 0.001). This data indicate that the elevated levels of serum Lp(a) and plasma t-PA-PAI-1 complex may play an important role in the pathogenesis of coronary atherosclerosis.
authors.affiliation: Department of Biochemistry, Istanbul University, Cerrahpaşa Medical Faculty, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Süer
authors.forename: T
authors.initials: T
authors.lastname: Ulutin
authors.forename: H
authors.initials: H
authors.lastname: Sönmez
authors.forename: E
authors.initials: E
authors.lastname: Kökoğlu
authors.forename: N
authors.initials: N
authors.lastname: Uçişik
authors.forename: C
authors.initials: C
authors.lastname: Bayram
authors.forename: G
authors.initials: G
authors.lastname: Sultuybek
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001161:Arteriosclerosis / Q000097:blood / Q000209:etiology; D016022:Case-Control Studies; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015243:Cholesterol, VLDL / Q000097:blood; D003327:Coronary Disease / Q000097:blood* / Q000209:etiology; D005260:Female; D006801:Humans; D017270:Lipoprotein(a) / Q000097:blood*; D008297:Male; D008875:Middle Aged; D017395:Plasminogen Activator Inhibitor 1 / Q000097:blood*; D010959:Tissue Plasminogen Activator / Q000097:blood*; D014280:Triglycerides / Q000097:blood
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D015243:Cholesterol, VLDL; D017270:Lipoprotein(a); D017395:Plasminogen Activator Inhibitor 1; D014280:Triglycerides; D002784:Cholesterol; D010959:Tissue Plasminogen Activator