Vitiligo is associated with HLA-A2 and HLA-Dw7 in the Slovak populations.
By investigating a group of 67 unrelated adult persons suffering from vitiligo it was found that antigens HLA-A2 and HLA-Dw7 differed in their frequencies in comparison to those observed in the healthy population. The antigen HLA-A2 was found in 76.12% of patients compared to 43.95% in the control group (chi 2 = 25.61, P < 0.005, RR = 4.07). The antigen HLA-Dw7 was present in 56.71% of patients compared to 15.8% in the healthy population (chi 2 = 26.55, P < 0.0001, RR = 6.98). No other significant deviations in the frequencies of investigated antigens were observed.
Buc
M
M
Department of Immunology, Faculty of Medicine, Comenius University, Bratislava, Slovak Republic.
Busová
B
B
Hegyi
E
E
Kolibásová
K
K
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D015789:HLA-A2 Antigen / Q000032:analysis*; D006681:HLA-D Antigens / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018154:Slovakia; D014820:Vitiligo / Q000276:immunology*
D015789:HLA-A2 Antigen; D006681:HLA-D Antigens