Micronutrient status of the besieged residents of Sarajevo: May 1993.
OBJECTIVE
To assess micronutrient status indices in blood and plasma of subjects subjected to siege conditions.


METHODS
Whole blood and serum samples were taken from subjects, sampled from 30 clusters in four Municipal Areas of Sarajevo. The blood samples were flown, under appropriate refrigeration, to the UK for analysis.


METHODS
The study was conducted in besieged Sarajevo and laboratory analyses were carried out at Department of Clinical Chemistry, Aberdeen Royal Infirmary and at Rowett Research Institute, Aberdeen, Scotland.


METHODS
202 subjects, aged from 1 to 82 years were included in the sample.


METHODS
Serum folate, ferritin, transferrin, retinol, retinol-binding protein, beta-carotene, alpha-tocopherol, 25-hydroxycholecalciferol, C-reactive protein, haemoglobin and mean corpuscular volume of blood were determined. Micronutrient status was assessed by comparison with a range of values derived from multinational data sets from both pathologically malnourished and normal subjects.


RESULTS
Haemoglobin, ferritin, folate, retinol and 25-hydroxycholecalciferol levels were lower in the Sarajevan sample than in normal reference populations. Serum alpha-tocopherol was low in children and adolescents while a low beta-carotene level probably reflected the scarcity of green vegetables. No consistent evidence of protein/energy deficits were detected.


CONCLUSIONS
Data for retinol binding protein and transferrin, when considered in association with BMI and Z-score data, provided no significant evidence of protein-energy undernutrition. However, the prevailing food aid rations failed to maintain adequate reserves of several micronutrients, particularly iron, folate and vitamin D. The significance of low values for serum retinol and beta-carotene and of low serum alpha-tocopherol in children must be investigated further.
Mardel
S
S
HANSA Unit, Rowett Research Institute, Bucksburn, Aberdeen.
Hailey
P C
PC
Mahmutovic
A
A
Broom
J
J
Golden
M H
MH
Franklin
M
M
Mills
C F
CF
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D001774:Blood Chemical Analysis; D001798:Blood Proteins; D015992:Body Mass Index; D017522:Bosnia and Herzegovina; D002648:Child; D002675:Child, Preschool; D005260:Female; D005293:Ferritins / Q000097:blood; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D012737:Sex Factors; D014857:Warfare
D001798:Blood Proteins; D005293:Ferritins