title: Longitudinal study on selenium content in human milk particularly during early lactation compared to that in infant formulas and cow's milk in Japan.
abstract: 239 samples of human breast milk were collected from 36 healthy Japanese women. Selenium content of the samples was determined mainly by highly sensitive fluorometric analysis with 2,3-diaminonaphthalene. The highest selenium content, 247 micrograms/kg, was found on the first day postpartum. The arithmetic mean of selenium content was higher in colostrum (< 4 days) 47 micrograms/kg (SD 42, n = 116) than in transitional milk 24 micrograms/kg (SD 13, n = 87) or in mature milk (> 10 days) 10 micrograms/kg (SD 4, n = 36). Selenium content was also determined for six brands of commercial infant formula powder (32-58 micrograms/kg) based on cow's milk, seventeen brands of cow's milk (10-25 micrograms/kg) and eight brands of powered cream for cofee (9-162 micrograms/kg). The average selenium content was significant lower in the liquid formula prepared for infant lactation, 6.0 micrograms/L, than in the human colostrum and transitional milk. The dietary selenium intake of newborns fed on colostrum is estimated to be in the range of 2-12 micrograms per day.
authors.affiliation: Department of Chemistry, Konan University, Kobe, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Tamari
authors.forename: K
authors.initials: K
authors.lastname: Chayama
authors.forename: H
authors.initials: H
authors.lastname: Tsuji
mesh_terms: D000818:Animals; D005260:Female; D006801:Humans; D007223:Infant; D007225:Infant Food / Q000032:analysis*; D007231:Infant, Newborn; D007564:Japan; D007774:Lactation; D008137:Longitudinal Studies; D008892:Milk / Q000737:chemistry*; D008895:Milk, Human / Q000737:chemistry*; D009751:Nutritional Requirements; D012643:Selenium / Q000008:administration & dosage / Q000032:analysis*; D013997:Time Factors
chemical_list: D012643:Selenium