Synthesis and properties of 2',5'-oligoadenylates containing alpha-adenosine.
Alpha-Adenosine analogs of 2'-5'Oligoadenylates (alpha 2-5 A) were synthesized by uranyl ion-catalyzed oligomerization of alpha-adenosine-5'-phosphorimidazolide in aqueous solution. alpha-Anomeric 3'-5'oligoadenylates were simultaneously formed in the oligomerization reaction. Physicochemical and biochemical properties of the resulting alpha 2-5 A were studied by spectroscopic and enzymatic method.
Ito
T
T
Department of Chemistry, Faculty of Engineering, Gunma University.
Kokaji
K
K
Shimazu
M
M
Shinozuka
K
K
Sawai
H
H
D000227:Adenine Nucleotides / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification; D000241:Adenosine / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D002942:Circular Dichroism; D015394:Molecular Structure; D009843:Oligoribonucleotides / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification
D000227:Adenine Nucleotides; D009843:Oligoribonucleotides; C023505:2',5'-oligoadenylate; D000241:Adenosine