title: Failure of postexposure treatment of rabies in children.
abstract: Five failures of postexposure treatment of rabies in small children with multiple severe bites on the face and head are discussed. All had received rabies immune globulin and a potent tissue-culture vaccine. However, not all wounds had been infiltrated with immune globulin. Surgical closure prior to wound injection with immune globulin was performed in three cases. Another patient had wounds sutured after an intramuscular injection of immune globulin, without wound infiltration.
authors.affiliation: Department of Medicine, Chulalonkorn University, Bangkok, Thailand.
authors.forename: H
authors.initials: H
authors.lastname: Wilde
authors.forename: S
authors.initials: S
authors.lastname: Sirikawin
authors.forename: A
authors.initials: A
authors.lastname: Sabcharoen
authors.forename: D
authors.initials: D
authors.lastname: Kingnate
authors.forename: T
authors.initials: T
authors.lastname: Tantawichien
authors.forename: P A
authors.initials: PA
authors.lastname: Harischandra
authors.forename: N
authors.initials: N
authors.lastname: Chaiyabutr
authors.forename: D G
authors.initials: DG
authors.lastname: de Silva
authors.forename: L
authors.initials: L
authors.lastname: Fernando
authors.forename: J B
authors.initials: JB
authors.lastname: Liyanage
authors.forename: V
authors.initials: V
authors.lastname: Sitprija
mesh_terms: D000818:Animals; D001733:Bites and Stings / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D008297:Male; D011818:Rabies / Q000628:therapy*; D011819:Rabies Vaccines / Q000627:therapeutic use*; D011820:Rabies virus / Q000276:immunology*; D017211:Treatment Failure; D014946:Wound Infection / Q000628:therapy
chemical_list: D011819:Rabies Vaccines