title: Failure of pretreatment with intravenous folic acid to alter the cumulative hematologic toxicity of lometrexol.
authors.forename: F M
authors.initials: FM
authors.lastname: Muggia
authors.forename: T W
authors.initials: TW
authors.lastname: Synold
authors.forename: E M
authors.initials: EM
authors.lastname: Newman
authors.forename: S
authors.initials: S
authors.lastname: Jeffers
authors.forename: L P
authors.initials: LP
authors.lastname: Leichman
authors.forename: J H
authors.initials: JH
authors.lastname: Doroshow
authors.forename: K
authors.initials: K
authors.lastname: Johnson
authors.forename: S
authors.initials: S
authors.lastname: Groshen
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects* / Q000493:pharmacokinetics; D004334:Drug Administration Schedule; D005260:Female; D005492:Folic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D005493:Folic Acid Antagonists / Q000009:adverse effects* / Q000493:pharmacokinetics; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D009369:Neoplasms / Q000188:drug therapy; D010198:Pancytopenia / Q000139:chemically induced / Q000517:prevention & control*; D013280:Stomatitis / Q000139:chemically induced / Q000517:prevention & control*; D013763:Tetrahydrofolates / Q000009:adverse effects* / Q000493:pharmacokinetics; D017211:Treatment Failure
chemical_list: D000964:Antimetabolites, Antineoplastic; D005493:Folic Acid Antagonists; D013763:Tetrahydrofolates; C045894:lometrexol; D005492:Folic Acid