title: The perinatal ontogeny of estrogen receptor-immunoreactivity in the developing male and female rat hypothalamus.
abstract: Developmental expression of the estrogen receptor (ER) in rat hypothalamus was examined using immunohistochemistry. In the medial preoptic nucleus and ventromedial nucleus ER-immunoreactivity was detected as early as E17, whereas ER protein expression in the periventricular preoptic nucleus and arcuate nucleus was delayed until E19. These results show that following a region specific onset of the ER protein expression sex differences in ER levels are already detectable during the perinatal period.
authors.affiliation: Department of Anatomy and Neurobiology, Kyoto Prefectural University of Medicine, Japan.
authors.forename: R J
authors.initials: RJ
authors.lastname: Pasterkamp
authors.forename: K
authors.initials: K
authors.lastname: Yuri
authors.forename: D T
authors.initials: DT
authors.lastname: Visser
authors.forename: S
authors.initials: S
authors.lastname: Hayashi
authors.forename: M
authors.initials: M
authors.lastname: Kawata
mesh_terms: D000818:Animals; D000918:Antibody Specificity; D005260:Female; D007031:Hypothalamus / Q000737:chemistry / Q000196:embryology* / Q000254:growth & development*; D007150:Immunohistochemistry; D008297:Male; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar; D011960:Receptors, Estrogen / Q000032:analysis / Q000276:immunology*; D012727:Sex Characteristics
chemical_list: D011960:Receptors, Estrogen