title: Cost-effectiveness modeling of simultaneous pancreas-kidney transplantation.
abstract: A cost-effectiveness model was developed to compare simultaneous pancreas-kidney transplantation (SPK) to kidney transplantation alone (KTA) with continued insulin therapy among type-1 diabetics with end-stage renal disease. It appeared that the two procedures were equally cost-effective only for diabetics whose annual costs for treatment of complications of hyper- and hypoglycemia were quite high.
authors.forename: T V
authors.initials: TV
authors.lastname: Holohan
mesh_terms: D003362:Cost-Benefit Analysis; D003922:Diabetes Mellitus, Type 1 / Q000191:economics* / Q000601:surgery; D017048:Health Care Costs; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000191:economics*; D018803:Models, Economic; D016035:Pancreas Transplantation / Q000191:economics*; D019057:Quality-Adjusted Life Years; D014481:United States
chemical_list: D007328:Insulin