[Creation of new supramolecular science with macrocyclic polyamines].
Exploitation of saturated macrocyclic polyamines has led to a discovery of numerous novel functions and new molecules such as (1) unique proton sponge properties; (2) uptake of biological polyanions; (3) peptide-like metal uptake properties; (4) stabilization of unusual oxidation states of metal ions (e.g. CuIII, NiIII); (5) novel uptake and activation of O2 by a new NiII-macrocyclic complex; (6) a new synthetic pathway to functionalize polyamines; (7) the first gold (III) complex that is a new candidate for gold-plating agents; (8) intrinsic zinc (II) properties pertinent to zinc enzymes; and (9) selective recognition of thymine by ZnII complexes. These newly discovered properties have created a way to a new type of supramolecular science.
Kimura
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E
Department of Medicinal Chemistry, School of Medicine, Hiroshima University, Japan.
D002412:Cations; D006046:Gold; D007477:Ions; D008666:Metalloendopeptidases; D011073:Polyamines; D000071228:Polyelectrolytes; D011108:Polymers; D011522:Protons; D000644:Quaternary Ammonium Compounds; D013941:Thymine; D015032:Zinc
D002412:Cations; D006046:Gold; D007477:Ions; D008666:Metalloendopeptidases; D011073:Polyamines; D000071228:Polyelectrolytes; D011108:Polymers; D011522:Protons; D000644:Quaternary Ammonium Compounds; D013941:Thymine; D015032:Zinc