title: Protein tyrosine phosphatases take off.
abstract: Protein tyrosine phosphatases (PTPs) are a family of signal transduction enzymes that dephosphorylate phosphotyrosine containing proteins. Structural and kinetic studies provide a molecular understanding of how these enzymes regulate a wide range of intracellular processes.
authors.affiliation: Laboratory of Molecular Biophysics, University of Oxford, UK.
authors.forename: D
authors.initials: D
authors.lastname: Barford
authors.forename: Z
authors.initials: Z
authors.lastname: Jia
authors.forename: N K
authors.initials: NK
authors.lastname: Tonks
mesh_terms: D000595:Amino Acid Sequence; D008969:Molecular Sequence Data; D011487:Protein Conformation; D017027:Protein Tyrosine Phosphatases / Q000737:chemistry* / Q000502:physiology* / Q000648:ultrastructure; D017386:Sequence Homology, Amino Acid; D015398:Signal Transduction / Q000502:physiology
chemical_list: D017027:Protein Tyrosine Phosphatases