Distribution of PGM1 and GC subtypes in the four Sardinian provinces.
Genetic polymorphism subtypes of PGM1 and GC were studied in four samples of the Sardinian population from the four Provinces of the island. The results show heterogeneity within the Sardinian population. The PGM1 alleles exhibiting the greatest variability were: PGM1*1S and PGM1*1F, with a range of .675-.724 (Nuoro - Sassari) and .072-.107 (Sassari - Nuoro) respectively. The observed GC allele frequency range were: GC*1F = .029-.168 (Cagliari - Sassari); GC*1S = .565-.752 (Sassari - Oristano); GC*2 = .194-.267 (Cagliari - Sassari). Sardinians showed a marked differentiation with respect to other Italian and European populations thus confirming their genetic peculiarity.
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Dipartimento di Biologia Sperimentale, Università di Cagliari, Italy.
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D000483:Alleles; D005006:Ethnicity / Q000235:genetics*; D005060:Europe / Q000453:epidemiology; D005787:Gene Frequency; D006801:Humans; D007527:Isoenzymes / Q000097:blood / Q000235:genetics*; D007558:Italy / Q000453:epidemiology; D010641:Phenotype; D010733:Phosphoglucomutase / Q000097:blood / Q000235:genetics*; D014809:Vitamin D-Binding Protein / Q000097:blood / Q000235:genetics*
D007527:Isoenzymes; D014809:Vitamin D-Binding Protein; D010733:Phosphoglucomutase