title: Interleukin 11 levels in patients with disseminated intravascular coagulation.
abstract: We assessed the blood interleukin 11 (IL-11) levels in patients with disseminated intravascular coagulation (DIC). The IL-11 level exceeded the detection limit, i.e., IL-11 was positive, in 14 of the 21 patients in the group with DIC complicated by sepsis, with a mean value of 20.4 pg/ml. In the group with DIC uncomplicated by infection, IL-11 levels were above the detection limit in 8 of the 17 patients, and the average level was 10.6 pg/ml. The difference between the IL-11-positive rate in the two groups was not significant. Although IL-11 levels tended to be higher in the group with sepsis as a complication, the difference was not significant. The elevated IL-11 levels observed in patients with DIC, with or without complication by infection, seem quite appropriate as a biological response to increased platelets.
authors.affiliation: Critical Care and Emergency Center, Iwate Medical University, Morioka, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Endo
authors.forename: K
authors.initials: K
authors.lastname: Inada
authors.forename: N
authors.initials: N
authors.lastname: Arakawa
authors.forename: Y
authors.initials: Y
authors.lastname: Yamada
authors.forename: H
authors.initials: H
authors.lastname: Nakae
authors.forename: T
authors.initials: T
authors.lastname: Takakuwa
authors.forename: M
authors.initials: M
authors.lastname: Namiki
authors.forename: Y
authors.initials: Y
authors.lastname: Inoue
authors.forename: T
authors.initials: T
authors.lastname: Shimamura
authors.forename: T
authors.initials: T
authors.lastname: Suzuki
authors.forename: S
authors.initials: S
authors.lastname: Taniguchi
authors.forename: M
authors.initials: M
authors.lastname: Yoshida
mesh_terms: D000328:Adult; D002056:Burns / Q000378:metabolism; D004211:Disseminated Intravascular Coagulation / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D017370:Interleukin-11 / Q000378:metabolism*; D018805:Sepsis / Q000378:metabolism; D014947:Wounds and Injuries / Q000378:metabolism
chemical_list: D017370:Interleukin-11