title: Primary and metastatic malignant tumors in soft tissue of skin. Diagnostic, surgical, and prognostic considerations for the foot.
abstract: Benign and malignant soft-tissue tumors are those that arise from mesenchymal (and some neuroectodermal) nonosteogenic and nonchondrogenic cells. The various primary malignant tumors are sarcomas with invasive and metastatic potential and are the same types that arise in the deeper tissues. In addition to sarcomas that arise directly in the dermis or subcutis, these tissue areas may be invaded by sarcomas from the deeper structures and by carcinomas and sarcomas metastatic to the skin. Dermal or subcutaneous cancers may appear clinically nondescript but are nonetheless dangerous, requiring an appropriately considered biopsy for identification and subsequent planning of patient care.
authors.affiliation: Franklin Delano Roosevelt Veterans Administration Hospital, Montrose, New York, USA.
authors.forename: G K
authors.initials: GK
authors.lastname: Potter
authors.forename: K A
authors.initials: KA
authors.lastname: Ward
mesh_terms: D002277:Carcinoma / Q000175:diagnosis / Q000473:pathology / Q000556:secondary / Q000601:surgery; D005354:Fibrosarcoma / Q000473:pathology; D005534:Foot Diseases / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology; D008080:Liposarcoma / Q000473:pathology; D009383:Neoplasms, Vascular Tissue / Q000473:pathology; D017599:Neuroectodermal Tumors / Q000473:pathology; D011379:Prognosis; D012509:Sarcoma / Q000175:diagnosis / Q000473:pathology / Q000556:secondary / Q000601:surgery; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000556:secondary / Q000601:surgery