Molecular forms of tegumental and muscle acetylcholinesterases of Schistosoma.
Acetylcholinesterase (AChE) is present in the muscle and on the tegument of schistosomes. Molecular forms of schistosome AChE were examined because particular AChEs are found in tissues of distinct function elsewhere. The dimeric globular form (G2) is the only form evident in adult Schistosoma haematobium: 32% of the muscle AChE is hydrophilic and 61% is membrane associated. A substantial amount of this enzyme is phosphatidylinositol (PI) anchored since it could be released by PI-specific phospholipase C from both muscle and tegumental membranes.
Camacho
M
M
Department of Biology, Imperial College of Science, Technology and Medicine, London.
Alsford
S
S
Agnew
A
A
D000110:Acetylcholinesterase / Q000032:analysis / Q000737:chemistry*; D000818:Animals; D002462:Cell Membrane / Q000201:enzymology; D017261:Glycosylphosphatidylinositols / Q000032:analysis; D015801:Helminth Proteins / Q000032:analysis / Q000737:chemistry*; D008970:Molecular Weight; D009132:Muscles / Q000201:enzymology; D012548:Schistosoma haematobium / Q000201:enzymology*; D010738:Type C Phospholipases
D017261:Glycosylphosphatidylinositols; D015801:Helminth Proteins; D000110:Acetylcholinesterase; D010738:Type C Phospholipases