Pathophysiology and management of VIPoma: a case study.
OBJECTIVE
To review the pathophysiology and clinical treatment of VIPomas, neuroendocrine tumors that secrete vasoactive intestinal polypeptide, and VIPoma syndrome.


METHODS
Published clinical treatments and case studies in the medical literature and case study data from a patient's medical record.


RESULTS
VIPomas are rare neuroendocrine tumors that cause a syndrome of life-threatening symptoms. Clinical management is complex, yet little information is available in the medical and nursing literature to guide the clinician.


CONCLUSIONS
Information about the pathophysiology and management of the disease may facilitate care of these patients.


CONCLUSIONS
A case study presentation provides an example of the care required by one patient with VIPoma. The nurse has an important role in assessing, educating, and caring for the patient with VIPoma. Interventions include managing complex fluid and electrolyte imbalances, chemotherapy administration and management of side effects, activity and rest alterations, safety issues, altered social roles, and educational needs regarding medications, central lines, and follow-up care.
Meriney
D K
DK
Acute/Tertiary Care Department, University of Pittsburgh School of Nursing, PA, USA.
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015994:Incidence; D012307:Risk Factors; D013004:Somatostatin / Q000009:adverse effects; D003969:Vipoma / Q000451:nursing / Q000503:physiopathology* / Q000628:therapy*
D000970:Antineoplastic Agents; D013004:Somatostatin