Effect of digital rectal examination on plasma prostate-specific antigen (PSA).
Presented are results of determination of plasma PSA before, 1 and 24 hours and 3 weeks after digital rectal examination (DRE) in 130 patients with prostatic adenoma (BPH). Mean pre-examination PSA level was 8.5 ng/ml (max. 27.0 ng/ml, min. 0.3 ng/ml, SD = 6.2). PSA rose at 1 and 24 hr. post-DRE: 9.4 ng/ml (max. 28.9 ng/ml, min. 0.5 ng/ml, SD = 6.7) and 10.7 ng/ml (max. 28.0 ng/ml, min. 0.5 ng/ml, SD = 7.9), respectively.


CONCLUSIONS
in patients with prostatic adenoma DRE is followed by a rise in plasma PSA, which returns almost to baseline values by 3 weeks.
Dutkiewicz
S
S
Department of Urology, Central Clinical Hospital, Ministry of Internal Affairs, Warsaw, Poland.
Stepień
K
K
Witeska
A
A
D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D006801:Humans; D008297:Male; D008875:Middle Aged; D010173:Palpation; D011467:Prostate; D017430:Prostate-Specific Antigen / Q000097:blood*; D011470:Prostatic Hyperplasia / Q000097:blood* / Q000175:diagnosis*
D014408:Biomarkers, Tumor; D017430:Prostate-Specific Antigen