The fate of glutamate in different brain regions of the chick during Newcastle disease virus infection.
Alterations in the glutamate metabolism during Newcastle disease virus (NDV) infection were studied in different brain regions of chick. The glutamate dehydrogenase, the glutamine synthetase, the glutamic acid decarboxylase activities were decreased and the glutamine content was decreased in all brain regions of chick after 24 hr. and 72 hr. of NDV infection. The results obtained in the present study reveal that the glutamate metabolism and its conversion to GABA were operated in low profile during NDV infection.
Lokanatha
V
V
Department of Zoology, Sri Venkateswara University, Tirupati, India.
Rajendra
W
W
D000818:Animals; D001921:Brain / Q000201:enzymology / Q000378:metabolism*; D002645:Chickens; D005968:Glutamate Decarboxylase / Q000378:metabolism; D005969:Glutamate Dehydrogenase / Q000378:metabolism; D005974:Glutamate-Ammonia Ligase / Q000378:metabolism; D018698:Glutamic Acid / Q000378:metabolism*; D008297:Male; D009521:Newcastle Disease / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid; D005969:Glutamate Dehydrogenase; D005968:Glutamate Decarboxylase; D005974:Glutamate-Ammonia Ligase