title: Colonic tubular adenomas and intestinal spirochaetosis: an incompatible association.
abstract: Two cases of tubulovillous adenoma and adjacent colonic mucosa were studied in which intestinal spirochaetosis had heavily colonized the non-neoplastic but not the neoplastic epithelium. Ultrastructural and histochemical studies were performed and we postulate that the reason for this disparity is the normal microvillous pattern of the non-neoplastic epithelium which facilitates colonization by the spirochaetes.
authors.affiliation: Department of Histopathology, South Manchester University Hospitals NHS Trust, Withington Hospital, UK.
authors.forename: J D
authors.initials: JD
authors.lastname: Coyne
authors.forename: A
authors.initials: A
authors.lastname: Curry
authors.forename: P
authors.initials: P
authors.lastname: Purnell
authors.forename: N Y
authors.initials: NY
authors.lastname: Haboubi
mesh_terms: D000236:Adenoma / Q000382:microbiology / Q000473:pathology* / Q000648:ultrastructure; D000368:Aged; D003108:Colonic Diseases / Q000382:microbiology / Q000473:pathology*; D003110:Colonic Neoplasms / Q000382:microbiology / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D008297:Male; D013145:Spirochaetales Infections / Q000473:pathology*