Inositol treatment of Alzheimer's disease: a double blind, cross-over placebo controlled trial.
1. A double-blind controlled crossover trial of 6 gm of inositol daily vs glucose for one month each was carried out in 11 Alzheimer patients. 2. Overall CAMCOG scores showed a trend for greater improvement with inositol that was not significant. 3. Language and orientation improved significantly more on inositol than on placebo. There were no serious side effects. 4. Higher doses of inositol should be studied in Alzheimer's Disease for longer periods.
Barak
Y
Y
Abarbanel Mental Health Center, Bat Yam, Israel.
Levine
J
J
Glasman
A
A
Elizur
A
A
Belmaker
R H
RH
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000188:drug therapy* / Q000523:psychology; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007294:Inositol / Q000627:therapeutic use*; D007802:Language; D009949:Orientation / Q000502:physiology; D011569:Psychiatric Status Rating Scales
D007294:Inositol