Cytokeratin profiles and mucin secretion in combined hepatocellular-cholangiocarcinoma. A case report.
A case of a combined hepatocellular-cholangiocarcinoma (HCC-CC) is presented showing mucin production in both the HCC and the CC component. Immunohistochemical staining for cytokeratins 7 and 19 was performed and it is concluded that immunoreactivity for cytokeratin 7 and 19 is an additional criterion to the detection of mucin in making the diagnosis of a combined HCC-CC of the transitional type.
Hauben
E
E
Department of Pathology, University Hospital Antwerp, Belgium.
Struyf
N
N
Michielsen
P
P
van Marck
E
E
D006528:Carcinoma, Hepatocellular / Q000276:immunology* / Q000378:metabolism; D002454:Cell Differentiation / Q000276:immunology; D018281:Cholangiocarcinoma / Q000276:immunology* / Q000378:metabolism; D005260:Female; D006801:Humans; D007633:Keratins / Q000032:analysis*; D008113:Liver Neoplasms / Q000276:immunology* / Q000378:metabolism; D008875:Middle Aged; D009077:Mucins / Q000032:analysis* / Q000378:metabolism*; D009378:Neoplasms, Multiple Primary / Q000145:classification / Q000276:immunology* / Q000378:metabolism
D009077:Mucins; D007633:Keratins