title: Glutamate receptor subtypes localize to patches in the developing striatum.
abstract: The distribution of glutamate receptors in the developing striatum of the rat was studied using antibodies specific to AMPA and NMDA subtypes. Immunocytochemistry revealed a greater density of GluR1, GluR2/3, NMDAR1, and NMDAR2A/2B receptors in patches that matched the patches of substance P-immunoreactive neurons and dopaminergic terminals. GluR1-immunoreactive patches were the most distinctive and were present already at embryonic day 19.
authors.affiliation: Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany 12201, USA. snykell@wadsworth.org
authors.forename: A
authors.initials: A
authors.lastname: Snyder-Keller
authors.forename: L C
authors.initials: LC
authors.lastname: Costantini
mesh_terms: D000344:Afferent Pathways / Q000502:physiology; D000818:Animals; D003342:Corpus Striatum / Q000737:chemistry* / Q000196:embryology; D005314:Embryonic and Fetal Development / Q000502:physiology; D005260:Female; D007150:Immunohistochemistry; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D018091:Receptors, AMPA / Q000032:analysis*; D016194:Receptors, N-Methyl-D-Aspartate / Q000032:analysis*
chemical_list: D018091:Receptors, AMPA; D016194:Receptors, N-Methyl-D-Aspartate