title: [20-year follow-up of hemophiliac patients infected with HIV].
abstract: In 1986 we detected serum antibodies against HIV in twenty four patients of our group of 84 cases of moderate to severe hemophilics. Twenty were asymptomatic to the acquired immunodeficiency syndrome (AIDS). After seven years, only three (15%) remain asymptomatic and seventeen (85%) developed AIDS. The mean time of development of AIDS was 56 months. Of these patients, fourteen (70%) have died. The median survival between the onset of the disease and death was eleven months. Only four of the patients that died received zidovudin, and in them we observed a median survival of 32 months.
authors.affiliation: Servicio de Infectología, Hospital de Especialidades, Monterrey, NL.
authors.forename: J J
authors.initials: JJ
authors.lastname: Ayala Gaytán
authors.forename: B G
authors.initials: BG
authors.lastname: Camacho Mezquita
authors.forename: G
authors.initials: G
authors.lastname: Rico Bazaldúa
authors.forename: R A
authors.initials: RA
authors.lastname: Canales García
authors.forename: M G
authors.initials: MG
authors.lastname: González Villarreal
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology; D000163:Acquired Immunodeficiency Syndrome / Q000401:mortality; D000293:Adolescent; D000998:Antiviral Agents / Q000627:therapeutic use; D015331:Cohort Studies; D015897:Comorbidity; D018450:Disease Progression; D005500:Follow-Up Studies; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology*; D006679:HIV Seropositivity / Q000453:epidemiology; D006467:Hemophilia A / Q000453:epidemiology*; D006801:Humans; D008800:Mexico / Q000453:epidemiology; D016019:Survival Analysis; D015215:Zidovudine / Q000627:therapeutic use
chemical_list: D000998:Antiviral Agents; D015215:Zidovudine