Giant cell tumor of the occipital bone in a case of von Recklinghausen neurofibromatosis.
Von Recklinghausen neurofibromatosis (NF1) is the most common hereditary syndrome predisposing to neoplasia. The most common symptomatic manifestation of NF1 is the plexiform neurofibroma. We describe the case of a patient with classical von Recklinghausen neurofibromatosis presenting with a giant cell tumor (GCT) of the occipital bone infiltrating a surrounding plexiform neurofibroma.
Opitz
H
H
Department of Neuropathology, University of Tübingen, Germany.
Petersen
D
D
Heiss
E
E
Duffner
F
F
Meyermann
R
R
D000328:Adult; D001859:Bone Neoplasms / Q000235:genetics / Q000473:pathology* / Q000648:ultrastructure; D018212:Giant Cell Tumor of Bone / Q000235:genetics / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D009456:Neurofibromatosis 1 / Q000235:genetics / Q000473:pathology*; D009777:Occipital Bone / Q000473:pathology*