title: [The mechanism of the anticonvulsive effect of the delta sleep-inducing peptide under conditions of elevated oxygen pressure].
abstract: Delta-sleep-inducing peptide (DSIP) exerted a protective effect against seizures, the effect depending on the DSIP ability to create an optimal ratio between inhibitory and excitatory amino acid neurotransmitters. Administration of the DSIP dramatically increased the contents of gamma-aminobutyric acid and homocarnosine while decreasing the glutamate and aspartate contents in the rat brain cortex.
authors.forename: A M
authors.initials: AM
authors.lastname: Mendzheritskiĭ
authors.forename: A V
authors.initials: AV
authors.lastname: Lysenko
authors.forename: N I
authors.initials: NI
authors.lastname: Uskova
authors.forename: E A
authors.initials: EA
authors.lastname: Sametskiĭ
mesh_terms: D000818:Animals; D000927:Anticonvulsants / Q000008:administration & dosage / Q000494:pharmacology*; D001273:Atmosphere Exposure Chambers; D001923:Brain Chemistry / Q000187:drug effects; D002540:Cerebral Cortex / Q000187:drug effects / Q000502:physiology; D003701:Delta Sleep-Inducing Peptide / Q000008:administration & dosage / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004567:Electrodes, Implanted; D006931:Hyperbaric Oxygenation / Q000009:adverse effects*; D008297:Male; D051381:Rats; D012640:Seizures / Q000209:etiology / Q000517:prevention & control
chemical_list: D000927:Anticonvulsants; D003701:Delta Sleep-Inducing Peptide