[The microcirculation in the mesentery of rats and thrombocyte aggregation during hypoglycemic coma].
Sensitivity of the rat arterioles to epinephrine was not changed in hypoglycaemic coma (HC). However, a double threshold dose of epinephrine induced a faster and stronger vasoconstriction in the HC. The thrombocyte ADP-inducing aggregation was lowered in the HC. The data obtained can be useful for correction of severe hypoglycaemic cases.
Shestakova
S A
SA
Mikhaĭlov
I F
IF
Stepanian
M L
ML
D000244:Adenosine Diphosphate / Q000494:pharmacology; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004837:Epinephrine / Q000494:pharmacology; D007331:Insulin Coma / Q000097:blood / Q000209:etiology / Q000503:physiopathology*; D008297:Male; D008643:Mesentery / Q000098:blood supply* / Q000187:drug effects; D008833:Microcirculation / Q000187:drug effects / Q000503:physiopathology; D010974:Platelet Aggregation / Q000187:drug effects / Q000502:physiology*; D051381:Rats
D000244:Adenosine Diphosphate; D004837:Epinephrine