title: Thyroid carcinoma as first manifestation of familial adenomatous polyposis.
abstract: A 22-year-old female member of a family with familial adenomatous polyposis (FAP) presented with a thyroid nodule. Histology revealed a follicular carcinoma. The patient was on regular follow-up as part of the FAP screening program; 1.5 years after the thyroidectomy she appeared to have multiple adenomatous polyps in her colon and FAP was diagnosed. Thyroid-carcinoma is one of the extraintestinal manifestations of FAP and particularly women in the age of 25-35 years are at risk according to the literature.
authors.affiliation: Department of Internal Medicine, Drechtsteden Ziekenhuis Refaja, Dordrecht, Netherlands.
authors.forename: J A
authors.initials: JA
authors.lastname: Stigt
authors.forename: H F
authors.initials: HF
authors.lastname: Vasen
authors.forename: K
authors.initials: K
authors.lastname: van der Linde
authors.forename: A C
authors.initials: AC
authors.lastname: van Vliet
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000175:diagnosis* / Q000601:surgery; D011125:Adenomatous Polyposis Coli / Q000175:diagnosis*; D000328:Adult; D005260:Female; D006801:Humans; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000601:surgery