Failure of pretreatment with intravenous folic acid to alter the cumulative hematologic toxicity of lometrexol.
Muggia
F M
FM
Synold
T W
TW
Newman
E M
EM
Jeffers
S
S
Leichman
L P
LP
Doroshow
J H
JH
Johnson
K
K
Groshen
S
S
D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects* / Q000493:pharmacokinetics; D004334:Drug Administration Schedule; D005260:Female; D005492:Folic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D005493:Folic Acid Antagonists / Q000009:adverse effects* / Q000493:pharmacokinetics; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D009369:Neoplasms / Q000188:drug therapy; D010198:Pancytopenia / Q000139:chemically induced / Q000517:prevention & control*; D013280:Stomatitis / Q000139:chemically induced / Q000517:prevention & control*; D013763:Tetrahydrofolates / Q000009:adverse effects* / Q000493:pharmacokinetics; D017211:Treatment Failure
D000964:Antimetabolites, Antineoplastic; D005493:Folic Acid Antagonists; D013763:Tetrahydrofolates; C045894:lometrexol; D005492:Folic Acid