Effect of X-rays on germ cells in female fetuses of Rattus norvegicus irradiated at three different times of gestation.
We analyzed the effect of X-rays on the number of recoverable germ cells in female rat fetuses irradiated at three different times of gestation: 14 days (oogonia), 16 days (leptotene) and 18 days (zygotene). Our results show that irradiation significantly decreases the number of germ cells, and increases the incidence of synaptonemal complex fragmentation. The different sensitivity of the germ cells to irradiation could depend on the meiotic stage at the time of irradiation.
Pujol
R
R
Departament de Biologia Cel.lular i Fisiologia, Facultat de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Cusidó
L
L
Rubio
A
A
Egozcue
J
J
Garcia
M
M
D000818:Animals; D005314:Embryonic and Fetal Development / Q000528:radiation effects; D005260:Female; D005333:Fetus / Q000528:radiation effects*; D005865:Gestational Age; D008540:Meiosis / Q000528:radiation effects; D010063:Ovum / Q000166:cytology / Q000254:growth & development / Q000528:radiation effects*; D011247:Pregnancy; D051381:Rats / Q000196:embryology*; D013573:Synaptonemal Complex / Q000528:radiation effects