title: [Pathogen spectrum and antibiotic resistance in peritonsillar abscess].
abstract: The study presented updates the spectrum of causative organisms in peritonsillar abscesses. Antibiotic treatment and surgery play important roles in this potentially life-threatening disease. A regular screening of the bacterial spectrum present and resistance remains important for optimizing a therapeutic regimen. Swabs of 122 peritonsillar abscesses were taken and investigated for the presence of causative organisms (bacteria and fungi) and potential antibiotic resistances. It was found that group A beta-hemolytic streptococci and Bacteroides spp. were the predominant isolates. It was also found that amoxicillin plus clavulinic acid or, alternatively, a third-generation cephalosporin (e.g., cefotaxime) represented the treatment of first choice to prevent antibiotic resistance.
authors.affiliation: Universitäts-HNO-Klinik Essen.
authors.forename: M
authors.initials: M
authors.lastname: Fischer
authors.forename: D
authors.initials: D
authors.lastname: Arweiler
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000658:Amoxicillin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D002439:Cefotaxime / Q000627:therapeutic use; D002511:Cephalosporins / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D004352:Drug Resistance, Microbial; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D000039:Peritonsillar Abscess / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D000658:Amoxicillin; D002439:Cefotaxime