title: Application of the dextran coupling method for analysis of interactions between intercalators and nucleotides.
abstract: Water-insoluble intercalators, acridine and pyrene, were converted to water-soluble species, Dex-Pyr and Dex-Acr, respectively, by coupling with dextran polymer. By the use of these dextran-coupled intercalators, interactions of acridine- and pyrene-skeletons with various nucleotides in aqueous solutions were analyzed.
authors.affiliation: Institute of Molecular and Cellular Biosciences, University of Tokyo, Japan.
authors.forename: O
authors.initials: O
authors.lastname: Nakajima
authors.forename: M
authors.initials: M
authors.lastname: Shichita
authors.forename: S
authors.initials: S
authors.lastname: Iwasaki
authors.forename: Y
authors.initials: Y
authors.lastname: Hashimoto
mesh_terms: D000166:Acridines / Q000737:chemistry; D003911:Dextrans / Q000737:chemistry*; D007364:Intercalating Agents / Q000737:chemistry*; D015394:Molecular Structure; D009711:Nucleotides / Q000737:chemistry*; D011721:Pyrenes / Q000737:chemistry; D012995:Solubility; D014867:Water
chemical_list: D000166:Acridines; D003911:Dextrans; D007364:Intercalating Agents; D009711:Nucleotides; D011721:Pyrenes; D014867:Water; C030984:pyrene