title: Chemotherapy alone in the treatment of patients with early stage Hodgkin's disease.
abstract: Studies employing chemotherapy in early stage Hodgkin's disease suggest that this approach is at least comparable to radiation therapy in treatment outcome. Since the long-term disease-free survival in early stages approaches 90%, it is unlikely to further improve these results substantially. Thus, the major goal is the reduction of toxicity. The future choice of therapy will be influenced by the long-term toxicity of these approaches which has to be monitored carefully.
authors.affiliation: Biological Response Modifiers Program, National Cancer Institute-Frederick Cancer Research and Development Center, MD, USA.
authors.forename: D L
authors.initials: DL
authors.lastname: Longo
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D006689:Hodgkin Disease / Q000188:drug therapy* / Q000532:radiotherapy; D006801:Humans; D009367:Neoplasm Staging