title: Medullary thyroid carcinoma imaged by Tc-99m MIBI SPECT and Tl-201 chloride/Tc-99m pertechnetate subtraction SPECT.
abstract: A 61-year-old man with medullary thyroid carcinoma and local invasion of the left lobe of the thyroid had Tc-99m MIBI SPECT and Tl-201 chloride/Tc-99m pertechnetate subtraction SPECT after left lobectomy of the thyroid, using a triple-headed gamma camera. Tl-201 chloride/Tc-99m pertechnetate subtraction demonstrated a large mass with high Tl-201 uptake in the left neck. Although there was intense uptake in the tumor in the left thyroid bed on Tc-99m MIBI neck SPECT, there was also uptake in both salivary glands and the right lobe of the thyroid gland. Thus, uptake in the right lobe of the thyroid gland and the salivary glands might not be differentiated from tumor invasion or metastasis from medullary cell carcinoma. Compared with MIBI SPECT, Tl-201 chloride/Tc-99m pertechnetate subtraction SPECT shows more apparent delineation of tumor uptake and may be a preferable technique.
authors.affiliation: Nuclear Medicine, Service Veterans Affairs Medical Center, Lexington, Kentucky 40511, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Shih
authors.forename: V
authors.initials: V
authors.lastname: Stipp
authors.forename: S
authors.initials: S
authors.lastname: Magoun
authors.forename: K B
authors.initials: KB
authors.lastname: Ain
authors.forename: C
authors.initials: C
authors.lastname: Pulmano
mesh_terms: D018276:Carcinoma, Medullary / Q000000981:diagnostic imaging* / Q000556:secondary / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D018365:Neoplasm, Residual; D012468:Salivary Gland Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D013670:Sodium Pertechnetate Tc 99m; D013382:Subtraction Technique; D017256:Technetium Tc 99m Sestamibi; D013793:Thallium; D013794:Thallium Radioisotopes; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
chemical_list: D013794:Thallium Radioisotopes; C027549:thallium chloride; D017256:Technetium Tc 99m Sestamibi; D013670:Sodium Pertechnetate Tc 99m; D013793:Thallium