title: Differential diagnosis of renal lesions with US-angiography using intra-arterial CO2 microbubbles.
abstract: To differentiate renal masses, 58 patients with renal masses (39 men and 19 women, aged 23-81 years [mean age 60 years]) underwent US-angiography with intra-arterial infusion of carbon dioxide (CO2) microbubbles during conventional angiography; 32 patients had renal cell carcinomas; nine, transitional cell carcinomas; nine, renal complicated cysts; four, angiomyolipomas; two, acute focal bacterial nephritis and hematomas. Renal masses were classified into six enhancement patterns of US-angiography. Thirty-one (97%) renal cell carcinomas were histologically alveolar type and demonstrated the well-enhancement pattern. All nine renal complicated cysts showed the non-enhancement pattern. Although transitional cell carcinomas did not show definite neovascularity on conventional angiography, they were classified as the well-enhancement pattern in 4/9 (44%) and poor-enhancement pattern in 5/9 (56%) on US-angiography. Four angiomyolipomas were homogeneously enhanced. Complicated cysts were clearly differentiated from renal cell carcinomas by the enhancement pattern on US-angiography. But the differentiation between renal cell carcinomas and angiomyolipomas was difficult. US-angiography is useful for detecting fine neovascularity of renal lesions and also for the differentiation or renal cell carcinomas from complicated cysts or transitional cell carcinomas during conventional angiography.
authors.affiliation: Department of Diagnostic Radiology, Gunma University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Horikoshi
authors.forename: H
authors.initials: H
authors.lastname: Ishizaka
authors.forename: T
authors.initials: T
authors.lastname: Moteki
authors.forename: M
authors.initials: M
authors.lastname: Matsumoto
mesh_terms: D018207:Angiomyolipoma / Q000000981:diagnostic imaging; D002245:Carbon Dioxide; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging; D002295:Carcinoma, Transitional Cell / Q000000981:diagnostic imaging; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D052177:Kidney Diseases, Cystic / Q000000981:diagnostic imaging; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D014463:Ultrasonography
chemical_list: D003287:Contrast Media; D002245:Carbon Dioxide