Detection of Campylobacter jejuni/C.coli infection in patients with Guillain-Barré syndrome by serology and culture.
Serum samples from 43 cases of Guillain-Barré Syndrome (GBS), 32 non-GBS neurology patients, and 35 healthy persons from a medical institute in Kerala, India, were tested for antibody levels against a Campylobacter jejuni strain Penner serotype 0:19 by agglutination and ELISA. Twenty-six percent of samples from GBS cases showed high antibody levels in all assays. Of 8 stool samples of new GBS cases examined by culture, 38% were positive for C. jejuni/C. col1. The results suggest that at least a quarter of GBS cases studied were associated with Campylobacter infection.
Hariharan
H
H
Department of Pathology and Microbiology, University of Prince Edward Island, Charlottetown, Canada.
Naseema
K
K
Kumaran
C
C
Shanmugam
J
J
Nair
M D
MD
Radhakrishnan
K
K
D000293:Adolescent; D000328:Adult; D000907:Antibodies, Bacterial / Q000097:blood; D001323:Autoantibodies / Q000097:blood; D002169:Campylobacter Infections / Q000382:microbiology*; D016123:Campylobacter jejuni / Q000276:immunology / Q000302:isolation & purification*; D002648:Child; D004926:Escherichia coli / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000382:microbiology; D005243:Feces / Q000382:microbiology; D005260:Female; D005677:G(M1) Ganglioside / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011129:Polyradiculoneuropathy / Q000276:immunology / Q000382:microbiology*
D000907:Antibodies, Bacterial; D001323:Autoantibodies; D005677:G(M1) Ganglioside