title: Phloroglucinols from Baeckea frutescens.
abstract: Two new phloroglucinols, named BF-1 and BF-2, were isolated from the dried leaves of Baeckea frutescens. Their structures were determined by their 1H and 13C NMR and mass spectral data. BF-2 exhibited strong cytotoxic activity (IC50 = 5.0 micrograms ml-1) against leukaemia cells (L 1210) in tissue culture.
authors.affiliation: College of Pharmacy, Nihon University, Chiba, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Fujimoto
authors.forename: S
authors.initials: S
authors.lastname: Usui
authors.forename: M
authors.initials: M
authors.lastname: Makino
authors.forename: M
authors.initials: M
authors.lastname: Sumatra
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification*; D001578:Benzopyrans / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D010696:Phloroglucinol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification; D010946:Plants, Medicinal / Q000737:chemistry*
chemical_list: D000972:Antineoplastic Agents, Phytogenic; C103056:BF-1 compound; C103057:BF-2 compound; D001578:Benzopyrans; D010696:Phloroglucinol