Still's disease in a patient infected with human immunodeficiency virus type I.
An autoreactive cellular immune response may be a part of HIV-1 infection. This autoimmune phenomenon also includes antibodies to collagen that can be associated to arthritis as a clinical condition. In this paper we describe a case of Still's disease in an adult HIV-1 infected patient who presented a marked amelioration in his condition after 15 days of steroid therapy, as well as an improvement of the arthritis. This rare autoimmune condition, which is connected with the disregulation of the immune system, must be taken into account in HIV-1 infected individuals who present with fever of unknown origin.
Antinori
S
S
Clinica delle Malattie Infettive, Università degli Studi di Milano, Italy.
Rusconi
S
S
Ridolfo
A L
AL
Orlando
G
G
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005335:Fever of Unknown Origin / Q000209:etiology*; D015658:HIV Infections / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D015497:HIV-1 / Q000276:immunology*; D006801:Humans; D007213:Indomethacin / Q000494:pharmacology; D008297:Male; D011241:Prednisone / Q000494:pharmacology; D016706:Still's Disease, Adult-Onset / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D013696:Temperature
D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D011241:Prednisone; D007213:Indomethacin