[Molecular mechanisms of cancer metastasis--ets-related nuclear transcription factor play an important role in cancer metastasis].
Significant progress has been made in the field of cancer metastasis, and the molecular mechanism of cancer metastasis is being studied extensively. Recent studies revealed that some oncogenes and metastasis-associated genes play important roles in cancer metastasis. Some nuclear transcription factors have appeared to be involved in this metastasis. Ets-related E1AF confers the invasive phenotype on cancer cells. E1AF that acts as a transcription factor is believed to play an important role in cancer invasiveness/metastasis through transcriptions of metastasis-related genes.
Kaya
M
M
Dept. of Molecular Biology, Sapporo Medical University, School of Medicine, Japan.
Yoshida
K
K
Fujinaga
K
K
D000818:Animals; D006801:Humans; D009361:Neoplasm Invasiveness / Q000235:genetics; D009362:Neoplasm Metastasis / Q000235:genetics*; D010641:Phenotype; D011519:Proto-Oncogenes / Q000502:physiology*; D014157:Transcription Factors / Q000502:physiology*; D014158:Transcription, Genetic
D014157:Transcription Factors