Bilateral medial temporal lobe damage without amnesic syndrome: a case report.
After the case report H.M. [42], unilateral neurosurgical interventions in the mediotemporal area have no longer been performed, if damage to the contralateral mediotemporal region was present, because of running the risk of provoking a postoperative amnesic syndrome. We present a patient with bilateral mediotemporal cysts and medically refractory complex partial seizures originating in the left mediotemporal region. Although our patient had additional right mediotemporal damage and poor non-verbal learning and memory, the left amygdaloid body and the left hippocampal formation were resected because the patient passed a selective anterior temporal lobe Amobarbital test. Postoperatively, our patient's non-verbal memory recovered to normal, but his verbal memory declined. Nevertheless, he was non-amnesic and seizure-free.
Henke
K
K
Center for Neuroscience, University of California at Davis, USA.
Wieser
H G
HG
D017668:Age of Onset; D000647:Amnesia; D000679:Amygdala / Q000473:pathology; D001927:Brain Diseases / Q000601:surgery*; D003560:Cysts / Q000601:surgery*; D017029:Epilepsy, Complex Partial / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D007839:Functional Laterality; D006624:Hippocampus / Q000473:pathology; D006801:Humans; D007858:Learning; D008279:Magnetic Resonance Imaging; D008297:Male; D008568:Memory; D008875:Middle Aged; D013060:Speech; D013577:Syndrome; D013702:Temporal Lobe / Q000473:pathology*