[Effect of n-nitrosodimethylamine (NDMA) on activity of selected enzymes in blood serum of the rat].
Changes in the activity of GOT, GPT, AP and GGTP in blood of rats intoxicated by low doses of N-Nitrosodimethylamine (NDMA) are presented. A significant increase in the activity of GOT and GPT was found after single doses (20 micrograms/kg b.w.) of NDMA as well as a significant increase in the activity of GOT, GPT, AP and GGTP after a prolonged intoxication per os by doses of 20 micrograms/dm3 given in drinking water.
Roszczenko
A
A
Miedzywydziałowej Katedry Toksykologii, Akademii Medycznej w Białymstoku.
Jabłoński
J
J
Moniuszko-Jakoniuk
J
J
D000284:Administration, Oral; D000818:Animals; D002273:Carcinogens / Q000008:administration & dosage / Q000633:toxicity*; D004123:Dimethylamines / Q000008:administration & dosage / Q000633:toxicity*; D008297:Male; D010744:Phosphoric Monoester Hydrolases / Q000097:blood / Q000187:drug effects*; D051381:Rats; D017208:Rats, Wistar; D014166:Transferases / Q000097:blood / Q000187:drug effects*
D002273:Carcinogens; D004123:Dimethylamines; D014166:Transferases; D010744:Phosphoric Monoester Hydrolases; C013962:dimethylnitramine