title: Localization of Tc-99m MDP in neuroblastoma metastases to the liver and lung.
abstract: Localization of skeletal tracer in a neuroblastoma primary is common but localization in extraskeletal metastatic sites has not received recognition. Tc-99m MDP concentration in hepatic or pulmonary metastases was noted in three of ten patients with such metastases. Lesion size appears to be important for demonstrating these metastases with Tc-99m MDP. This was particularly true for hepatic metastases, which were identified only when they were 5 cm or greater in diameter.
authors.affiliation: Department of Radiology, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
authors.forename: L P
authors.initials: LP
authors.lastname: Connolly
authors.forename: D A
authors.initials: DA
authors.lastname: Bloom
authors.forename: H
authors.initials: H
authors.lastname: Kozakewich
authors.forename: F A
authors.initials: FA
authors.lastname: Hoffer
authors.forename: S T
authors.initials: ST
authors.lastname: Treves
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000378:metabolism; D002114:Calcinosis / Q000000981:diagnostic imaging / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D003287:Contrast Media; D005260:Female; D005500:Follow-Up Studies; D005682:Gadolinium; D006801:Humans; D007089:Image Enhancement; D007223:Infant; D007231:Infant, Newborn; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary*; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary*; D008279:Magnetic Resonance Imaging; D008297:Male; D009367:Neoplasm Staging; D009447:Neuroblastoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary*; D013902:Radiography, Thoracic; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D012189:Retrospective Studies; D013669:Technetium Tc 99m Medronate / Q000493:pharmacokinetics
chemical_list: D003287:Contrast Media; D019275:Radiopharmaceuticals; D005682:Gadolinium; D013669:Technetium Tc 99m Medronate