title: Select transition zone prostate cancers may be radiocurable despite markedly elevated prostate-specific antigen levels.
abstract: In 1993, three men with transition zone prostate cancers were described (Stamey et al., J. Urol. 149: 510-515, 1993) who despite high prostate-specific antigen (PSA) levels remained PSA failure-free at 22 months postoperatively. This report illustrates that prolonged PSA failure free survival may be achieved when external beam radiation therapy is used to treat similar patients.
authors.affiliation: Department of Radiation Oncology, Harvard Medical School, North Dartmouth, MA 02747, USA.
authors.forename: A V
authors.initials: AV
authors.lastname: D'Amico
authors.forename: I
authors.initials: I
authors.lastname: Kaplan
mesh_terms: D000206:Actuarial Analysis; D000230:Adenocarcinoma / Q000097:blood / Q000473:pathology / Q000532:radiotherapy*; D018572:Disease-Free Survival; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood / Q000473:pathology / Q000532:radiotherapy*; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy; D012189:Retrospective Studies
chemical_list: D017430:Prostate-Specific Antigen