title: [The effect of epiphysectomy and destruction of the lateral septal nucleus of the brain on the genital system in juvenile rats under different light regimens (the interaction of gonadostat++ and photoperiodic mechanisms in the regulation of ovarian functions)].
abstract: Results of experimental investigations of the effect of the epiphysectomy and brain lateral septal nucleus (LSN) destruction on the morphofunctional conditions of the genital system of juvenile female white rats kept under different illumination conditions are described. The analysis of consequences of epiphysectomy and LSN destruction as well as of these operative influences taken together shows that the morphofunctional condition of the female genital apparatus changes more intensively in rats kept under the constant illumination and less intensively in those kept under variation of light and darkness, which affected the estradiol production function of rats. A conclusion is made that the epiphysis influences the hypothalamo-hypophysis-ovary system (HHOS) in case of the intact LSN, and efficiency of the LSN effect on the HHOS depends on the presence of the epiphysis. Some possible mechanisms of interaction and integration of the gonadostat and photoperiodic mechanisms of the HHOS function regulation are discussed.
authors.forename: O V
authors.initials: OV
authors.lastname: Slaetna
authors.forename: H I
authors.initials: HI
authors.lastname: Khodorovs'kyĭ
mesh_terms: D000818:Animals; D004564:Electrocoagulation; D005260:Female; D008027:Light; D010053:Ovary / Q000502:physiology*; D017440:Photoperiod; D010870:Pineal Gland / Q000502:physiology* / Q000601:surgery; D010902:Pituitary Gland / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D012686:Septal Nuclei / Q000502:physiology* / Q000601:surgery; D014599:Uterus / Q000502:physiology