Field evaluation of arthropod repellents, deet and a piperidine compound, AI3-37220, against Anopheles funestus and Anopheles arabiensis in western Kenya.
A field evaluation of the repellents N,N-diethyl-3-methylbenzamide (deet) and 1-(3-cyclohexen-1-yl-carbonyl)-2-methylpiperidine (AI3-37220, a piperidine compound) was conducted against Anopheles funestus and An. arabiensis in Kenya. Both repellents provided significantly more protection (P < 0.001) than the ethanol control. AI3-37220 was significantly more effective (P < 0.001) than deet in repelling both species of mosquitoes. After 9 h, 0.1 mg/cm2 of AI3-37220 provided 89.8% and 71.1% protection against An. arabiensis and An. funestus, respectively. Deet provided > 80% protection for only 3 h, and protection rapidly decreased after this time to 60.2% and 35.1% for An. arabiensis and An. funestus, respectively, after 9 h. Anopheles funestus was significantly less sensitive (P < 0.001) to both repellents than An. arabiensis. The results of this study indicate that AI3-37220 is more effective than deet in repelling anopheline mosquitoes in western Kenya.
Walker
T W
TW
United States Army Center for Health Promotion, Preventive Medicine, Divisional Support Activity-West, Aurora, CO 80045-5001, USA.
Robert
L L
LL
Copeland
R A
RA
Githeko
A K
AK
Wirtz
R A
RA
Githure
J I
JI
Klein
T A
TA
D000328:Adult; D000818:Animals; D000852:Anopheles; D003671:DEET; D006801:Humans; D007302:Insect Repellents; D007630:Kenya; D008297:Male; D009032:Mosquito Control / Q000379:methods*; D010880:Piperidines
D007302:Insect Repellents; D010880:Piperidines; D003671:DEET; C075892:1-(3-cyclohexen-1-ylcarbonyl)-2-methylpiperidine