title: Oxyphil parathyroid adenoma associated with primary hyperparathyroidism and marked post-operative hungry bone syndrome.
abstract: A rare case of functioning oxyphil parathyroid adenoma associated with primary hyperparathyroidism and marked hungry bone syndrome was revealed in a 29-year-old man with hypercalcemia and elevated circulating parathyroid hormone (PTH) level. A large parathyroid tumor weighing 8.4 g was resected and proved to be an oxyphil adenoma. Hypocalcemia was sustained after the operation, despite intensive calcium supplementation. During the postoperative 8 months, bone mineral density at the lumbar spine increased dramatically from 0.892 g/cm2 to 1.244 g/cm2, and whole body bone mineral content increased from 1,913.4 g to 2,419.2 g. This case gives insight to the reversibility of bone loss in this disorder.
authors.affiliation: Department of Medicine and Clinical Science, Kyoto University, Graduate School of Medicine.
authors.forename: K
authors.initials: K
authors.lastname: Natsui
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: M
authors.initials: M
authors.lastname: Suda
authors.forename: A
authors.initials: A
authors.lastname: Yasoda
authors.forename: C
authors.initials: C
authors.lastname: Shigeno
authors.forename: J
authors.initials: J
authors.lastname: Konishi
authors.forename: K
authors.initials: K
authors.lastname: Nakao
mesh_terms: D018249:Adenoma, Oxyphilic / Q000150:complications* / Q000601:surgery; D000328:Adult; D015519:Bone Density; D001847:Bone Diseases / Q000150:complications* / Q000378:metabolism; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications*; D008297:Male; D010282:Parathyroid Neoplasms / Q000150:complications* / Q000601:surgery; D013577:Syndrome; D013997:Time Factors