Intraneural biphasic synovial sarcoma: an alternative "glandular" tumor of peripheral nerve.
A primary intraneural biphasic synovial sarcoma that arose within the common digital nerve of the hand is reported. The patient, a 16-year-old girl, presented with a small soft tissue mass that clinically and intraoperatively resembled a nerve sheath tumor. The diagnosis of synovial sarcoma was established on the basis of a typical light microscopic appearance and immunohistochemical staining profile. Intraneural biphasic synovial sarcoma resembles "glandular" peripheral nerve sheath tumor, because both are composed of a mixture of spindled mesenchymal cells with admixed glandular epithelial elements. The features allowing differentiation of these two unusual tumors of peripheral nerve are discussed.
O'Connell
J X
JX
Department of Pathology, Vancouver Hospital and Health Sciences Centre, British Columbia, Canada.
Browne
W L
WL
Gropper
P T
PT
Berean
K W
KW
D000293:Adolescent; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D009375:Neoplasms, Glandular and Epithelial / Q000276:immunology* / Q000473:pathology*; D010524:Peripheral Nervous System Neoplasms / Q000276:immunology / Q000473:pathology*; D013584:Sarcoma, Synovial / Q000276:immunology / Q000473:pathology*