RNA splicing: unexpected spliceosome diversity.
A novel form of spliceosome, containing the minor snRNPs U11 and U12, splices a class of pre-mRNA introns with non-consensus splice sites. This unexpected spliceosome diversity has interesting implications for the evolution and expression of eukaryotic genes.
Kreivi
J P
JP
Department of Biochemistry, University of Dundee, Scotland, UK.
Lamond
A I
AI
D000818:Animals; D006801:Humans; D007438:Introns; D009687:Nuclear Proteins / Q000235:genetics*; D012322:RNA Precursors; D012326:RNA Splicing; D017411:Ribonucleoproteins, Small Nuclear / Q000378:metabolism*; D017381:Spliceosomes; D012359:tRNA Methyltransferases
D009687:Nuclear Proteins; D012322:RNA Precursors; D017411:Ribonucleoproteins, Small Nuclear; C098762:U11 small nuclear ribonucleoprotein, human; C552126:U11-U12 small nuclear ribonucleoprotein; C065028:NOP2 protein, human; D012359:tRNA Methyltransferases