A case of an infertile man with short-tailed spermatozoa.
Ejaculated spermatozoa from an infertile patient were examined by scanning and transmission electron microscopy. All spermatozoa had abnormalities in the tail region. The abnormalities were divided into three types: (a) spermatozoa with a spherical tail. The tail was larger than the head in volume. This type of abnormality accounted for about 60% of the population; (b) spermatozoa with a blunt tail. The tails were about 2 microns in diameter and about 7 microns in length. This type of abnormality accounted for about 30% of the population of an ejaculate; (c) spermatozoa without a tail. Some of these had only a rudimentary tail. About 10% of the population belonged to this type. In types A and B, all components of the tail, except for dynein arms, were observed, but they were severely disarranged. Biopsy specimens of the testes and of the nasal mucosa of this patient were also investigated. The testicular biopsy showed defects in manchette formation. Normal development of the manchette could not be observed. The nasal epithelium showed absence of the inner dynein arms in the cilia.
Toyama
Y
Y
Department of Anatomy, School of Medicine, Chiba University, Japan.
Sumiya
H
H
Fuse
H
H
Shimazaki
J
J
D000328:Adult; D004542:Ejaculation; D006801:Humans; D007248:Infertility, Male / Q000473:pathology*; D008297:Male; D009297:Nasal Mucosa / Q000648:ultrastructure; D013082:Sperm Tail / Q000648:ultrastructure*; D013737:Testis / Q000648:ultrastructure