title: Ceftazidime resistance among Klebsiella pneumoniae in south India.
abstract: Fifteen strains of K. pneumoniae resistant to ceftazidime were tested for extended spectrum beta lactamase (ESBL) production by double disc diffusion synergy test using ceftazidime and augmentin, and by testing for reduction in minimum inhibitory concentration of ceftazidime in combination with clavulanic acid. All strains were found to produce ESBL. We document the presence of ESBL producing strains in south India. There is a possibility of the spread of this resistance to other bacteria because the resistance could be transferred to recipient Escherichia coli from two strains.
authors.affiliation: Department of Microbiology, Christian Medical College & Hospital, Vellore.
authors.forename: S
authors.initials: S
authors.lastname: Abigail
authors.forename: E
authors.initials: E
authors.lastname: Mathai
authors.forename: M V
authors.initials: MV
authors.lastname: Jesudason
authors.forename: T J
authors.initials: TJ
authors.lastname: John
mesh_terms: D002442:Ceftazidime / Q000494:pharmacology*; D004058:Diffusion; D004352:Drug Resistance, Microbial; D007194:India; D007711:Klebsiella pneumoniae / Q000187:drug effects*; D001618:beta-Lactamases / Q000096:biosynthesis
chemical_list: D002442:Ceftazidime; D001618:beta-Lactamases