Oxyphil parathyroid adenoma associated with primary hyperparathyroidism and marked post-operative hungry bone syndrome.
A rare case of functioning oxyphil parathyroid adenoma associated with primary hyperparathyroidism and marked hungry bone syndrome was revealed in a 29-year-old man with hypercalcemia and elevated circulating parathyroid hormone (PTH) level. A large parathyroid tumor weighing 8.4 g was resected and proved to be an oxyphil adenoma. Hypocalcemia was sustained after the operation, despite intensive calcium supplementation. During the postoperative 8 months, bone mineral density at the lumbar spine increased dramatically from 0.892 g/cm2 to 1.244 g/cm2, and whole body bone mineral content increased from 1,913.4 g to 2,419.2 g. This case gives insight to the reversibility of bone loss in this disorder.
Natsui
K
K
Department of Medicine and Clinical Science, Kyoto University, Graduate School of Medicine.
Tanaka
K
K
Suda
M
M
Yasoda
A
A
Shigeno
C
C
Konishi
J
J
Nakao
K
K
D018249:Adenoma, Oxyphilic / Q000150:complications* / Q000601:surgery; D000328:Adult; D015519:Bone Density; D001847:Bone Diseases / Q000150:complications* / Q000378:metabolism; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications*; D008297:Male; D010282:Parathyroid Neoplasms / Q000150:complications* / Q000601:surgery; D013577:Syndrome; D013997:Time Factors