Hepatocellular carcinomas diagnosed following metastasis to the oral cavity. Report of 2 cases.
Oral metastases from hepatocellular carcinomas are rare. Case 1 was a 66-year-old male without previous history of liver disease who presented with metastasis to the gingival jaw mucosae on the lingual side. Case 2 was a 71-year-old male, with a previous history of diabetes, hepatitis, and cirrhosis who presented with metastasis to the right palatine tonsil. Oral metastases were the first manifestation of the hepatocellular carcinoma in both cases. A review of the literature disclosed 20 cases of hepatocellular carcinoma metastasizing to the oral cavity, 7 affecting the gingival mucosae and none of them affecting the palatine tonsil.
Llanes
F
F
Departamento Anatomia Patologica, Hospital Universitario San Carlos, Madrid, Spain.
Sanz-Ortega
J
J
Suarez
B
B
Sanz-Esponera
J
J
D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis / Q000556:secondary*; D017809:Fatal Outcome; D005887:Gingival Neoplasms / Q000556:secondary*; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D014067:Tonsillar Neoplasms / Q000556:secondary*