New and forthcoming therapies for viral hepatitis.
Therapies for chronic viral hepatitis B and C are aimed at clearing the virus and producing a sustained immunity. Manipulation of the biological response would confer an antiviral state and modulate the immune responses. For the development of new therapeutic agents against hepatitis viruses, reliable in vitro models are needed to study drug effects. Forthcoming therapies might combine natural or synthetic antiviral compounds and cytokines, together with novel approaches including anti-sense oligonucleotides and ribozymes.
Carreño
V
V
Hepatology Unit, Fundación Jiménez Diaz, Madrid, Spain.
Quiroga
J A
JA
D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000627:therapeutic use; D006509:Hepatitis B / Q000628:therapy*; D006526:Hepatitis C / Q000628:therapy*; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use; D007376:Interleukin-2 / Q000627:therapeutic use
D016898:Interferon-alpha; D007376:Interleukin-2; D016179:Granulocyte Colony-Stimulating Factor; D016178:Granulocyte-Macrophage Colony-Stimulating Factor