title: [A patient with unresectable cancer of pancreas head, effectively treated by a local injection of the mixture of OK-432, fibrinogen and thrombin].
abstract: The effective treatment of unresectable pancreatic cancer remains to be elucidated. We report herein a patient who underwent a local injection of a mixture of OK-432, fibrinogen and thrombin. Tumor size and tumor markers significantly decreased following this procedure. Local injection therapy with OK-432, fibrinogen and thrombin may be a promising treatment for unresectable pancreatic cancer.
authors.affiliation: Dept. of Surgery II, Osaka University Medical School.
authors.forename: K
authors.initials: K
authors.lastname: Takekuni
authors.forename: M
authors.initials: M
authors.lastname: Sakon
authors.forename: S
authors.initials: S
authors.lastname: Kishimoto
authors.forename: M
authors.initials: M
authors.lastname: Amano
authors.forename: M
authors.initials: M
authors.lastname: Sekimoto
authors.forename: T
authors.initials: T
authors.lastname: Aoki
authors.forename: H
authors.initials: H
authors.lastname: Oosato
authors.forename: K
authors.initials: K
authors.lastname: Dohno
authors.forename: K
authors.initials: K
authors.lastname: Umeshita
authors.forename: M
authors.initials: M
authors.lastname: Gotoh
authors.forename: T
authors.initials: T
authors.lastname: Monden
authors.forename: M
authors.initials: M
authors.lastname: Monden
mesh_terms: D000230:Adenocarcinoma / Q000628:therapy*; D004359:Drug Therapy, Combination; D005340:Fibrinogen / Q000008:administration & dosage*; D006801:Humans; D015552:Injections, Intralesional; D010190:Pancreatic Neoplasms / Q000628:therapy*; D010844:Picibanil / Q000008:administration & dosage*; D013917:Thrombin / Q000008:administration & dosage*
chemical_list: D010844:Picibanil; D005340:Fibrinogen; D013917:Thrombin