The molecular control mechanisms of meiosis in fission yeast.
Recent experiments have shown that the inactivation of a protein kinase, pat1, and the activation of an RNA-binding protein, mei2, commit fission yeast cells to enter meiosis. Both the cyclic AMP cascade and the mitogen-activated protein kinase cascade seem to be involved in this activation/inactivation. An RNA molecule that cooperates with mei2 to play a critical role in the promotion of meiosis I has also been identified.
Yamamoto
M
M
Department of Biophysics and Biochemistry, School of Science, University of Tokyo, Japan.
D005656:Fungal Proteins / Q000235:genetics*; D008540:Meiosis / Q000235:genetics; D012331:RNA, Fungal / Q000235:genetics*; D016601:RNA-Binding Proteins / Q000235:genetics*; D012568:Schizosaccharomyces / Q000235:genetics / Q000254:growth & development*; D029702:Schizosaccharomyces pombe Proteins
D005656:Fungal Proteins; D012331:RNA, Fungal; D016601:RNA-Binding Proteins; D029702:Schizosaccharomyces pombe Proteins; C088896:mei2 protein, S pombe