title: Genetic polymorphisms of red cell enzymes in tribes of Andhra Pradesh, India.
abstract: The genetic heterogeneity of some common red cell enzyme markers among four endogamous tribal populations namely Konda Dora, Kotia, Bod Mali and Manzai Mali was investigated by starch/polyacrylamide/cellulose acetate gel electrophoresis. ACP, ESD, PGM1, G6PD, AK1, ADA, 6PGD enzymes and haemoglobin exhibited a polymorphism. PGM2, LDH, MDH, SOD, GOT, CA1, CA2 and GPI were monomorphic. A slow variant of SOD similar to that found in SOD 2-1 heterozygote was observed with a frequency of 1.31% among Kotia tribe. Most populations of the present study were in Hardy-Weinberg equilibrium for the majority of the genetic markers examined. The results are discussed in the light of available data on other Andhra populations.
authors.affiliation: Department of Anthropology, Andhra University, Visakhapatnam, India.
authors.forename: J M
authors.initials: JM
authors.lastname: Naidu
authors.forename: B V
authors.initials: BV
authors.lastname: Babu
authors.lastname: Yasmin
authors.forename: S S
authors.initials: SS
authors.lastname: Devi
mesh_terms: D000328:Adult; D000368:Aged; D001797:Blood Protein Electrophoresis; D001798:Blood Proteins / Q000235:genetics*; D003241:Consanguinity; D004912:Erythrocytes / Q000201:enzymology*; D005006:Ethnicity / Q000235:genetics*; D005260:Female; D005819:Genetic Markers; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011110:Polymorphism, Genetic
chemical_list: D001798:Blood Proteins; D005819:Genetic Markers