Leukaemia cutis in chronic CD8+ T lymphocytic leukaemia.
A 66-year-old woman with CD8+ chronic lymphocytic leukaemia developed multiple indurated erythema or plaques. A skin biopsy specimen showed dense infiltration of leukaemia cells in the dermis and subcutaneous tissue. Most of the infiltrating cells were CD8 + cells. To our best knowledge, leukaemia cutis such as this case showing plaques with diffuse infiltration of CD8 + cells has not been reported previously.
Kishimoto
H
H
Department of Dermatology, School of Medicine, Tokyo Medical and Dental University, Japan.
Mamada
A
A
Katayama
I
I
Nishioka
K
K
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D018414:CD8-Positive T-Lymphocytes / Q000166:cytology*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D015461:Leukemia, Prolymphocytic, T-Cell / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D017254:Leukemic Infiltration / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D012867:Skin / Q000473:pathology*