[Resistance of Pseudomonas mallei to tetracyclines: assessment of the feasibility of chemotherapy].
The spectrum of cross resistance in tetracycline resistant strains of Pseudomonas mallei was studied. Possible use of antibacterial drugs in the prevention and treatment of mallel due to such strains was investigated in the experiments on golden hamsters and monkeys. It was shown that the efficacy of the minocycline therapy depended on the level of the strain resistance to tetracycline antibiotics. The combination of biseptol and ofloxacin proved to be highly efficient in the treatment of mallei.
Manzeniuk
I N
IN
Manzeniuk
O Iu
OIu
Filonov
A V
AV
Stepanshin
Iu G
IuG
Svetoch
E A
EA
D000818:Animals; D006224:Cricetinae; D005240:Feasibility Studies; D008647:Mesocricetus; D008826:Microbial Sensitivity Tests; D010215:Papio; D011549:Pseudomonas / Q000187:drug effects*; D011552:Pseudomonas Infections / Q000188:drug therapy* / Q000517:prevention & control; D013753:Tetracycline Resistance / Q000502:physiology*