title: Site-specific hydrolysis of yeast tRNAPhe by anthraquinone-glycine and anthraquinone-iminodiacetate conjugates.
abstract: Site-specific hydrolysis of yeast tRNAPhe was performed by anthraquinone-glycine conjugate (Anth-Gly) and anthraquinone-iminodiacetate conjugate (Anth-IDA) under physiological conditions. The cleavages by Anth-Gly occurred selectively at the stems, whereas the cleavage by Anth-IDA are restricted to the D-loop, the extra-loop, and the T psi C-stem.
authors.affiliation: Department of Chemistry and Biotechnology, Graduate School of Engineering, University of Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Endo
authors.forename: K
authors.initials: K
authors.lastname: Hirata
authors.forename: T
authors.initials: T
authors.lastname: Inokawa
authors.forename: K
authors.initials: K
authors.lastname: Matsumura
authors.forename: M
authors.initials: M
authors.lastname: Komiyama
authors.forename: T
authors.initials: T
authors.lastname: Ihara
authors.forename: S
authors.initials: S
authors.lastname: Sueda
authors.forename: M
authors.initials: M
authors.lastname: Takagi
mesh_terms: D000880:Anthraquinones / Q000737:chemistry / Q000494:pharmacology*; D001483:Base Sequence; D001665:Binding Sites; D005998:Glycine / Q000494:pharmacology; D006868:Hydrolysis; D007097:Imines / Q000494:pharmacology; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009690:Nucleic Acid Conformation; D012331:RNA, Fungal / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D012360:RNA, Transfer, Phe / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D012441:Saccharomyces cerevisiae / Q000737:chemistry / Q000235:genetics
chemical_list: D000880:Anthraquinones; D007097:Imines; D012331:RNA, Fungal; D012360:RNA, Transfer, Phe; D005998:Glycine