title: Migrating monopredominant arthritis in children of Assyrian ancestry.
abstract: We describe an unusual form of arthritis affecting 3 Assyrian children to inspire a search for further cases to determine how unique it may be. After different patterns of onset, 3 of 4 children with arthritis from the Assyrian community in northern California had an unusual course of recurrent arthritis, predominantly in one joint at a time. There was rapid cartilage and bone destruction in involved joints. The 3 children are HLA-DR4. The 4th patient had a more typical childhood polyarticular course. Two of the first 3 patients had fever with attacks. None had rheumatoid factor, antinuclear antibody, or the HLA-B27 antigen. This unusual, severe, monopredominant but migrating arthritis appears to be particularly associated with Assyrian descent.
authors.affiliation: Department of Pediatrics, Stanford University School of Medicine, California, USA.
authors.forename: J J
authors.initials: JJ
authors.lastname: Miller
authors.forename: H M
authors.initials: HM
authors.lastname: Emery
mesh_terms: D000293:Adolescent; D000843:Ankle Joint / Q000000981:diagnostic imaging / Q000473:pathology; D001168:Arthritis / Q000208:ethnology* / Q000276:immunology / Q000473:pathology; D002140:California; D002675:Child, Preschool; D005260:Female; D005858:Germany; D006680:HLA Antigens / Q000032:analysis; D006650:Histocompatibility Testing; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008877:Middle East / Q000208:ethnology; D011859:Radiography; D012008:Recurrence; D013583:Synovial Membrane / Q000473:pathology; D014955:Wrist Joint / Q000000981:diagnostic imaging / Q000473:pathology
chemical_list: D006680:HLA Antigens