title: A study of spermatozoal motility in type 1 diabetes mellitus.
abstract: The aim of the study was to examine an aspect of male fertility in patients with Type 1 diabetes mellitus (n = 17) compared to healthy control subjects (n = 16) using parameters of sperm motility, measured using a computerized image analysis system (the Hamilton Thorn Research HTM-2030 Motility Analyzer), as indicators of potential fertility. Within the diabetic group no correlations were found between sperm motility and age, age of onset of diabetes, duration of diabetes or glycated haemoglobin. When the diabetic and control groups were compared, track speed, path velocity, progressive velocity, and lateral head displacement were not significantly different, whereas linearity and linear index, measures of straightness of swimming, were significantly greater in the diabetic subjects (59.2% vs 69.8%, p = 0.0005 and 76.4% vs 83.6%, p = 0.0016, respectively). We conclude that diabetic men, in the absence of complications, do not appear to be at a disadvantage in terms of sperm motility compared to healthy individuals.
authors.affiliation: Medical Unit, Royal London Hospital, United Kingdom.
authors.forename: M J
authors.initials: MJ
authors.lastname: Niven
authors.forename: G A
authors.initials: GA
authors.lastname: Hitman
authors.forename: D F
authors.initials: DF
authors.lastname: Badenoch
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D016001:Confidence Intervals; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000503:physiopathology*; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D008297:Male; D018715:Microscopy, Video / Q000379:methods; D008875:Middle Aged; D012016:Reference Values; D013081:Sperm Motility
chemical_list: D006442:Glycated Hemoglobin