[Effect of cigarette smoking on T and NK cell count in blood of persons occupationally exposed to organic solvents].
The studies covered 139 men including two control groups: 40 nonsmokers and 41 smokers occupationally exposed to organic solvents. The results of toxicological analysiss of the air revealed the presence of benzene, toluene, xylene and their hydrogenated derivatives, paraffin hydrocarbons, oleins, naphthenes, alcohols (butanol, cyclohexanol), esters (ethylglycol acetate, butyl acetate) and ketones methyl isobutyl ketone, cyclohexanon). Absolute number of lymphocytes, T lymphocytes (CD 3+), T-helper (CD 4+), T-suppressor (CD 8+) and NK-cells (CD +16) were determined in the peripheral blood by indirect immunofluorescence test. A decreased number of lymphocytes and NK-cells as well as an increased number of T-suppressor lymphocytes were noted. That contributed to the decrease of T-helper/T-suppressor ratio in the subjects occupationally exposed to organic solvents. Cigarette smoking enhanced this disorder.
Moszczyński
P
P
Z Wojewódzkiej Pracownii Immunologicznej w Brzesku.
Rutowski
J
J
Slowiński
S
S
D000293:Adolescent; D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects* / Q000032:analysis; D004784:Environmental Monitoring; D006801:Humans; D007694:Killer Cells, Natural / Q000187:drug effects*; D018655:Lymphocyte Count / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D012907:Smoking / Q000276:immunology*; D012997:Solvents / Q000009:adverse effects*; D013601:T-Lymphocytes / Q000187:drug effects*
D000395:Air Pollutants, Occupational; D012997:Solvents