title: Cytokeratin profiles and mucin secretion in combined hepatocellular-cholangiocarcinoma. A case report.
abstract: A case of a combined hepatocellular-cholangiocarcinoma (HCC-CC) is presented showing mucin production in both the HCC and the CC component. Immunohistochemical staining for cytokeratins 7 and 19 was performed and it is concluded that immunoreactivity for cytokeratin 7 and 19 is an additional criterion to the detection of mucin in making the diagnosis of a combined HCC-CC of the transitional type.
authors.affiliation: Department of Pathology, University Hospital Antwerp, Belgium.
authors.forename: E
authors.initials: E
authors.lastname: Hauben
authors.forename: N
authors.initials: N
authors.lastname: Struyf
authors.forename: P
authors.initials: P
authors.lastname: Michielsen
authors.forename: E
authors.initials: E
authors.lastname: van Marck
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000276:immunology* / Q000378:metabolism; D002454:Cell Differentiation / Q000276:immunology; D018281:Cholangiocarcinoma / Q000276:immunology* / Q000378:metabolism; D005260:Female; D006801:Humans; D007633:Keratins / Q000032:analysis*; D008113:Liver Neoplasms / Q000276:immunology* / Q000378:metabolism; D008875:Middle Aged; D009077:Mucins / Q000032:analysis* / Q000378:metabolism*; D009378:Neoplasms, Multiple Primary / Q000145:classification / Q000276:immunology* / Q000378:metabolism
chemical_list: D009077:Mucins; D007633:Keratins