title: Synthesis and pharmacology of a very potent cannabinoid lacking a phenolic hydroxyl with high affinity for the CB2 receptor.
authors.affiliation: Department of Chemistry, Clemson University, South Carolina 29634-1905, USA.
authors.forename: J W
authors.initials: JW
authors.lastname: Huffman
authors.forename: S
authors.initials: S
authors.lastname: Yu
authors.forename: V
authors.initials: V
authors.lastname: Showalter
authors.forename: M E
authors.initials: ME
authors.lastname: Abood
authors.forename: J L
authors.initials: JL
authors.lastname: Wiley
authors.forename: D R
authors.initials: DR
authors.lastname: Compton
authors.forename: B R
authors.initials: BR
authors.lastname: Martin
authors.forename: R D
authors.initials: RD
authors.lastname: Bramblett
authors.forename: P H
authors.initials: PH
authors.lastname: Reggio
mesh_terms: D000818:Animals; D002186:Cannabinoids / Q000737:chemistry; D002462:Cell Membrane / Q000378:metabolism; D004192:Discrimination, Psychological / Q000187:drug effects; D013759:Dronabinol / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000378:metabolism; D006801:Humans; D015394:Molecular Structure; D010636:Phenols; D051381:Rats; D043885:Receptor, Cannabinoid, CB2; D043882:Receptors, Cannabinoid; D011955:Receptors, Drug / Q000378:metabolism*; D013329:Structure-Activity Relationship
chemical_list: D002186:Cannabinoids; C469526:Cnr2 protein, rat; D010636:Phenols; D043885:Receptor, Cannabinoid, CB2; D043882:Receptors, Cannabinoid; D011955:Receptors, Drug; C101717:1',2'-dimethylheptyl-1-deoxy-delta(8)-tetrahydrocannabinol; D013759:Dronabinol