Medical fetal therapy.
Medical fetal therapy describes any therapy in which a pharmacological agent is administered to a woman or her fetus in order to avoid or alleviate fetal disease. Treatment of the fetus with blood products or injection of other agents can also be considered to be medical fetal therapy. This chapter reviewed the application of medical fetal therapy to the prevention of NTDs, treatment of endocrinological and metabolic disorders, such as CAH, thyroid disease and others, and the medical management of cardiac arrhythmias. Several haematological disorders and reviews of recent advances in genetic manipulation involving the use of stem-cell implantation were discussed. The field of medical fetal therapy has been extremely exciting and continues to evolve at a rapid pace. No doubt, future advances involving genetic manipulation or the use of molecular genetic techniques for diagnosis will continue to keep this field at the forefront of treatment and prevention of fetal disorders.
Yankowitz
J
J
Department of Obstetrics and Gynecology, University of Iowa College of Medicine, Iowa City 52242-1080, USA.
Weiner
C
C
D001145:Arrhythmias, Cardiac / Q000628:therapy; D004700:Endocrine System Diseases / Q000628:therapy; D005315:Fetal Diseases / Q000628:therapy*; D006402:Hematologic Diseases / Q000628:therapy; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008659:Metabolic Diseases / Q000628:therapy; D009436:Neural Tube Defects / Q000517:prevention & control