title: Scoliosis in cerebral gigantism, Sotos syndrome. A case report.
abstract: METHODS
  This retrospective study reviewed five patients with scoliosis associated with cerebral gigantism (Sotos syndrome).
  
  
  OBJECTIVE
  To clarify the clinical characteristics and progression of scoliosis in patients with cerebral gigantism. SUMMARY OF BACKGROUND DATA. Little has been reported about spinal deformity in this syndrome.
  
  
  METHODS
  The records and radiographs of five patients were reviewed.
  
  
  RESULTS
  Scoliosis was first noticed at the age of 5 years in one case and at 6-16 months in the others. Their curve patterns were not consistent. Cobb's angles increased rapidly by 4 years of age and after 8 years of age despite attempts at bracing.
  
  
  CONCLUSIONS
  Excessive growth in infancy and growth-spurt period after 8 years of age may be related to the rapid progression of scoliosis in the same period.
authors.affiliation: Department of Pediatric Orthopedics, Shizuoka Children's Hospital, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Haga
authors.forename: S
authors.initials: S
authors.lastname: Nakamura
authors.forename: M
authors.initials: M
authors.lastname: Shimode
authors.forename: Y
authors.initials: Y
authors.lastname: Yanagisako
authors.forename: T
authors.initials: T
authors.lastname: Iwaya
mesh_terms: D001921:Brain / Q000002:abnormalities*; D002675:Child, Preschool; D005260:Female; D005877:Gigantism / Q000150:complications*; D006128:Growth / Q000502:physiology; D006801:Humans; D007223:Infant; D008297:Male; D011859:Radiography; D012189:Retrospective Studies; D012600:Scoliosis / Q000150:complications* / Q000601:surgery; D013131:Spine / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery