title: Scrub typhus complicating acute respiratory distress syndrome: a report of two cases.
abstract: Scrub typhus is a zoonotic disease, caused by Rickettsia tsutsugamushi, in which humans are accidental hosts. Although it is an acute febrile illness, severe complications of this disease are very rare since the introduction of specific antibiotic therapy. The authors report two cases of scrub typhus complicating acute respiratory distress syndrome. The first case progressed to multiple organ failure, and the patient expired. In the second case, the patient recovered and was discharged. These two cases were proved to be scrub typhus by their travel history or their having lived in endemic area, clinical manifestations, an eschar and indirect immunofluorescent antibody test. For a good prognosis, early diagnosis and early treatment of this disease are important.
authors.affiliation: Department of Medicine, Veterans General Hospital-Taipei, Taiwan, R.O.C.
authors.forename: W S
authors.initials: WS
authors.lastname: Lee
authors.forename: F D
authors.initials: FD
authors.lastname: Wang
authors.forename: L S
authors.initials: LS
authors.lastname: Wang
authors.forename: W W
authors.initials: WW
authors.lastname: Wong
authors.forename: D
authors.initials: D
authors.lastname: Young
authors.forename: C P
authors.initials: CP
authors.lastname: Fung
authors.forename: C Y
authors.initials: CY
authors.lastname: Liu
mesh_terms: D005260:Female; D006801:Humans; D008875:Middle Aged; D012128:Respiratory Distress Syndrome / Q000209:etiology*; D012612:Scrub Typhus / Q000150:complications*