title: Side reactions in the pyroglutamic acid-7-amino-4-methylcoumarin synthesis.
abstract: N-Formylpyroglutamic acid-7-amido-4-methylcoumarine and pyroglutamyl-pyroglutamic acid-7-amido-4-methylcoumarin are the major products in the synthesis of pyroglutamic acid-7-amido-4-methylcoumarin by phosphorus pentachloride in dimethylformamide and dicyclohexylcarbodiimide under pyridine activation.
authors.affiliation: Department of Chemistry, Technical University, Riga, Latvia.
authors.forename: D
authors.initials: D
authors.lastname: Zicane
authors.forename: M
authors.initials: M
authors.lastname: Petrova
authors.forename: Z
authors.initials: Z
authors.lastname: Tetere
authors.forename: G
authors.initials: G
authors.lastname: Kreishman
authors.forename: E
authors.initials: E
authors.lastname: Brooks
authors.forename: J
authors.initials: J
authors.lastname: Karlson
authors.forename: U
authors.initials: U
authors.lastname: Kalejs
mesh_terms: D002712:Chlorides / Q000737:chemistry; D003374:Coumarins / Q000138:chemical synthesis* / Q000737:chemistry*; D004024:Dicyclohexylcarbodiimide / Q000737:chemistry; D010758:Phosphorus / Q000737:chemistry; D017553:Phosphorus Compounds; D011761:Pyrrolidonecarboxylic Acid / Q000737:chemistry* / Q000031:analogs & derivatives
chemical_list: D002712:Chlorides; D003374:Coumarins; D017553:Phosphorus Compounds; C102731:pyroglutamic acid 7-amino-4-methylcoumarin; D010758:Phosphorus; D004024:Dicyclohexylcarbodiimide; C043693:phosphorus chloride; C028743:7-amino-4-methylcoumarin; D011761:Pyrrolidonecarboxylic Acid