Sonographic appearance of the endometrium and ovaries during cycles stimulated with human menopausal gonadotropin.
OBJECTIVE
To determine the measurable factors that correlated with a higher conception ratio in one of our subpopulations of infertility patients.


METHODS
We analyzed 58 menstrual cycles in 24 consecutive infertility patients treated only with human menopausal gonadotropin (hMG) and intrauterine insemination between January 1992 and February 1993 to compare those cycles leading to conception with those that did not with regard to certain factors: endometrial thickness, endometrial layering, number of follicles > or = 15 mm in diameter, peak estradiol level and number of cycles prior to conception.


RESULTS
All conceptions occurred in cycles that showed endometrial layering. No patient conceived if the endometrial thickness was < 8 mm. The incidence of conception increased with the number of follicles (one to three) measuring > 15 mm in average diameter. No patient conceived if the serum estradiol was < 192 pg/mL. No conceptions occurred after three successive cycles of treatment.


CONCLUSIONS
Endometrial layering, endometrial thickness of at least 8 mm, a higher number of follicles (up to three) with an average of 15 mm and a serum estradiol level of at least 192 pg/mL correlated with a higher rate of conception.
Reuter
K L
KL
Department of Radiology, University of Massachusetts Medical Center, Worcester 01655, USA.
Cohen
S
S
Furey
L
L
Baker
S
S
D000328:Adult; D004717:Endometrium / Q000166:cytology / Q000000981:diagnostic imaging* / Q000187:drug effects*; D004958:Estradiol / Q000097:blood; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000097:blood / Q000188:drug therapy / Q000503:physiopathology; D008596:Menotropins / Q000494:pharmacology* / Q000627:therapeutic use; D008597:Menstrual Cycle / Q000187:drug effects / Q000502:physiology*; D008875:Middle Aged; D006080:Ovarian Follicle / Q000166:cytology / Q000502:physiology; D010053:Ovary / Q000000981:diagnostic imaging* / Q000187:drug effects* / Q000502:physiology; D010060:Ovulation / Q000187:drug effects / Q000502:physiology; D011247:Pregnancy; D018873:Pregnancy Rate; D014463:Ultrasonography
D004958:Estradiol; D008596:Menotropins