title: The contribution of conventional and quantitative electroencephalography during monitoring of exposure to hyperbaric oxygen.
abstract: In the present study, experimental exposures to hyperbaric oxygen (HBO) were performed (30-min exposure to 2.8 bar pure oxygen). During all phases of the experiment the electroencephalogram (EEG) was recorded continuously for on-line visual monitoring and off-line quantitative analysis. Conventional and quantitative EEG findings are described for a group of 23 subjects during an uncomplicated HBO exposure and for one subject who had a generalized tonic-clinic seizure when exposed to HBO. In the group of subjects who did not show signs of toxicity, EEG changes were minor and were not considered indicative of an adverse effect of HBO on the brain during the HBO exposure. Pre-convulsive EEG changes were detected in the subject with the seizure but were too insignificant for practical monitoring purposes and did not clearly herald clinical signs.
authors.affiliation: Department of Clinical Neurophysiology, Rudolf Magnus Institute for Neurosciences, Utrecht University, The Netherlands.
authors.forename: G H
authors.initials: GH
authors.lastname: Visser
authors.forename: R A
authors.initials: RA
authors.lastname: van Hulst
authors.forename: G H
authors.initials: GH
authors.lastname: Wieneke
authors.forename: A C
authors.initials: AC
authors.lastname: van Huffelen
mesh_terms: D000328:Adult; D000513:Alpha Rhythm; D000704:Analysis of Variance; D001611:Beta Rhythm; D001921:Brain / Q000187:drug effects* / Q000503:physiopathology; D004569:Electroencephalography / Q000379:methods; D004830:Epilepsy, Tonic-Clonic / Q000503:physiopathology; D006801:Humans; D006931:Hyperbaric Oxygenation / Q000009:adverse effects*; D010100:Oxygen / Q000009:adverse effects*; D013997:Time Factors
chemical_list: D010100:Oxygen