title: Prostate-specific antigen and prostatitis in men under fifty.
abstract: OBJECTIVE
  To evaluate the occurrence of increased prostate-specific antigen (PSA) serum concentration in patients with prostatitis and low incidence of benign prostatic hyperplasia and prostatic cancer, PSA was measured in a selected population.
  
  
  METHODS
  PSA levels were evaluated in 72 patients with prostatitis under 50 years of age.
  
  
  RESULTS
  An increased PSA (> 4 ng/ml) was found in 5/7 (71%) patients with acute prostatitis, and in 2/13 (15%) and 2/32 (6%) patients with chronic bacterial and abacterial prostatitis, respectively. No patient with prostatodynia had an increased PSA. In patients with bacterial prostatitis PSA level decreased to normal value after effective antibiotic therapy in most cases.
  
  
  CONCLUSIONS
  Prostatitis must be considered when using PSA as tumor marker.
authors.affiliation: Department of Urology, S. Camillo Hospital, Rome, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Pansadoro
authors.forename: P
authors.initials: P
authors.lastname: Emiliozzi
authors.forename: L
authors.initials: L
authors.lastname: Defidio
authors.forename: P
authors.initials: P
authors.lastname: Scarpone
authors.forename: G
authors.initials: G
authors.lastname: Sabatini
authors.forename: A
authors.initials: A
authors.lastname: Brisciani
authors.forename: S
authors.initials: S
authors.lastname: Lauretti
mesh_terms: D000328:Adult; D001424:Bacterial Infections / Q000097:blood / Q000175:diagnosis / Q000382:microbiology; D015415:Biomarkers / Q000097:blood; D001707:Biopsy, Needle; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood*; D011472:Prostatitis / Q000097:blood* / Q000175:diagnosis / Q000382:microbiology; D012189:Retrospective Studies
chemical_list: D015415:Biomarkers; D017430:Prostate-Specific Antigen