title: Synthesis and properties of 5-fluorouracil oligonucleotides.
abstract: Oligonucleotides of 5-fluoro-2'-deoxyuridine (FUdR) 1 and 5-fluorouridine (FUR) 2 have been prepared by the standard phosphoramidite method. Homo oligomers (24 mer) of 1, 2 and hetero oligomers of those will be described.
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Ehime University, Matsuyama, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Koga
authors.forename: T
authors.initials: T
authors.lastname: Yasusa
authors.forename: M
authors.initials: M
authors.lastname: Yamamoto
authors.forename: S
authors.initials: S
authors.lastname: Haba
authors.forename: T
authors.initials: T
authors.lastname: Suzuki
authors.forename: T
authors.initials: T
authors.lastname: Saeki
authors.forename: S
authors.initials: S
authors.lastname: Ozaki
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D005467:Floxuridine / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D015394:Molecular Structure; D009841:Oligonucleotides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D014529:Uridine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000964:Antimetabolites, Antineoplastic; D009841:Oligonucleotides; D005467:Floxuridine; C001943:5-fluorouridine; D014529:Uridine