[The effect of antibodies to S-100 proteins on synaptogenesis processes and learning in rats].
In newborn rats passively immunised with the brain-specific protein (BSP) S-100, obvious ultrastructural changes occurred in the glial cells, density of desmosomal contacts increased and the density of synaptic contacts in neurophile of the supraoptic nuclei of the hypothalamus decreased. The S-100 proteins seem to fulfil a regulatory function in synaptogenesis in both newborn and adult animals.
Babichenko
I I
II
Storozheva
Z I
ZI
Medvedev
D I
DI
Sherstnev
V V
VV
D000818:Animals; D000831:Animals, Newborn; D000906:Antibodies / Q000494:pharmacology*; D001921:Brain / Q000187:drug effects / Q000648:ultrastructure; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology; D005247:Feeding Behavior / Q000187:drug effects / Q000502:physiology; D005260:Female; D007116:Immunization, Passive; D018782:Maze Learning / Q000187:drug effects* / Q000502:physiology; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D017208:Rats, Wistar; D009418:S100 Proteins / Q000276:immunology*; D013569:Synapses / Q000187:drug effects* / Q000648:ultrastructure
D000906:Antibodies; D009418:S100 Proteins