title: Morphologic characteristics of restenotic lesions following coronary interventions: balloon angioplasty versus directional atherectomy: can we speculate about the mechanism of restenosis from morphologic analysis?
abstract: In order to compare the processes of restenosis after balloon angioplasty as compared to that after directional coronary atherectomy, we performed qualitative and quantitative analysis of 72 lesions in 68 patients with recurrent ischemia following a successful initial procedure. For each lesion, we reviewed the pre-intervention, immediate post-intervention, and restenosis angiograms. The morphology of the restenotic lesions could not be predicted from pre- or post-intervention angiograms. The restenotic lesions after directional atherectomy, as compared to balloon angioplasty, did not show a statistically significant difference, although there was a trend to more eccentric narrowing.
authors.affiliation: Cardiac Unit, Massachusetts General Hospital, Boston 02114, USA.
authors.forename: J
authors.initials: J
authors.lastname: Moreu
authors.forename: M T
authors.initials: MT
authors.lastname: Silver
authors.forename: I F
authors.initials: IF
authors.lastname: Palacios
authors.forename: I K
authors.initials: IK
authors.lastname: Jang
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D017225:Atherectomy, Coronary; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012307:Risk Factors; D016896:Treatment Outcome