title: The effects of ageing and changes in mineral content in degrading the toughness of human femora.
abstract: Static toughness and impact strength of human cortical bone decline with age. This decline is strongly associated with an increase in the ash content of the bones but other factors, associated with age, are probably also responsible for the degradation of the bones' mechanical properties.
authors.affiliation: Department of Biology, University of York, U.K.
authors.forename: J D
authors.initials: JD
authors.lastname: Currey
authors.forename: K
authors.initials: K
authors.lastname: Brear
authors.forename: P
authors.initials: P
authors.lastname: Zioupos
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000378:metabolism / Q000502:physiology*; D015519:Bone Density / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D004735:Energy Transfer; D005264:Femoral Fractures / Q000378:metabolism / Q000503:physiopathology*; D005269:Femur / Q000737:chemistry / Q000502:physiology*; D006801:Humans; D016014:Linear Models; D008875:Middle Aged; D008903:Minerals / Q000032:analysis; D013314:Stress, Mechanical
chemical_list: D008903:Minerals; C028705:bone ash