title: Evaluation of an automated auditory brainstem response infant hearing screening method in at risk neonates.
abstract: An automated auditory brainstem response (ABR) method-the ALGO-1 Plus- has been developed for hearing screening in healthy neonates. The aim of this study was to test the validity of this automated ABR screening method in at-risk neonates in a neonatal intensive care unit. Two hundred and fifty at-risk neonates were selected for screening according to the criteria of the American Joint Commerce on Infant Hearing. All 250 neonates were screened with the ALGO-1 Plus for bilateral hearing loss. When two consecutive screenings pointed to bilateral hearing loss ("refer") further audiological investigations were performed and where necessary therapeutic measures were taken. All children who "passed" the screening unilateral or bilateral enrolled in a nationwide behavioural screening programme at the age of 9 months as well as in a 6-monthly follow up programme documenting speech and language development. A total of 245 (98%) neonates passed the ALGO-1 screening, 230 (92%) at the first attempt and 15 (6%) at the second attempt. Five (2%) were referred with bilateral hearing loss. One of these died of congenital rubella shortly after screening and bilateral congenital hearing loss of > 35 dB was confirmed in the other 4. None of the infants who passed the screening were discovered to have moderate to severe bilateral hearing loss (> 40 dB) with behavioural screening (n = 183/233) or at follow up (n = 233/233). In this study, all at-risk neonates with bilateral congenital hearing loss were detected with ALGO-1 Plus screening. No false-negatives were discovered.
  
  
  CONCLUSIONS
  The ALGO-1 Plus infant hearing screener can be used as a valid automated ABR-screener to detect hearing loss in at-risk neonates in a neonatal intensive care setting.
authors.affiliation: University of Amsterdam, Department of Neonatology, The Netherlands.
authors.forename: H L
authors.initials: HL
authors.lastname: van Straaten
authors.forename: M E
authors.initials: ME
authors.lastname: Groote
authors.forename: A M
authors.initials: AM
authors.lastname: Oudesluys-Murphy
mesh_terms: D016057:Evoked Potentials, Auditory, Brain Stem; D005500:Follow-Up Studies; D006312:Hearing Loss, Bilateral / Q000175:diagnosis*; D006320:Hearing Tests / Q000295:instrumentation; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D015203:Reproducibility of Results; D012307:Risk Factors