title: Pergolide treatment for Cushing's syndrome in a horse.
abstract: A 16-year-old, male, Hanoverian horse had a three-month history of weight loss, hirsutism and polyuria/polydypsia. Examinations revealed neutrophilia, lymphopenia, hyper glycaemia and abnormalities in hepatic function. A tentative diagnosis of hyperadrenocorticism was made. The results of thyroid-releasing hormone and combined dexamethasone suppression and ACTH stimulation tests suggested the presence of a pituitary adenoma. The horse was treated with pergolide and beneficial clinical and biochemical responses were observed within one to six months.
authors.affiliation: Departamento de Patología Animal, Facultad de Veterinaria, Universidad de Las Palmas de Gran Canaria, Spain.
authors.forename: M C
authors.initials: MC
authors.lastname: Muñoz
authors.forename: F
authors.initials: F
authors.lastname: Doreste
authors.forename: O
authors.initials: O
authors.lastname: Ferrer
authors.forename: J
authors.initials: J
authors.lastname: González
authors.forename: J A
authors.initials: JA
authors.lastname: Montoya
mesh_terms: D000818:Animals; D003480:Cushing Syndrome / Q000188:drug therapy / Q000662:veterinary*; D018491:Dopamine Agonists / Q000627:therapeutic use*; D006734:Horse Diseases / Q000188:drug therapy*; D006736:Horses; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D010479:Pergolide / Q000627:therapeutic use*
chemical_list: D018491:Dopamine Agonists; D010479:Pergolide; D006854:Hydrocortisone