Immunoreactive Phe-Met-Arg-Phe-NH2-like peptides in the brain of the antarctic icefish, Chionodraco hamatus.
The distribution of Phe-Met-Arg-Phe-NH2 (FMRFamide)-like immunoreactive peptides was investigated in the brain of the antarctic icefish, Chionodraco hamatus, using the indirect immunofluorescence technique. Three main groups of immunoreactive perikarya were respectively localized in the nucleus entopeduncularis of the telencephalon, the nucleus preopticus periventricularis of the hypothalamus, and within the nucleus oculomotorius of the mesencephalon. Delicate FMRFamide positive nerve fibers were distributed in several brain regions of the forebrain and brainstem. In particular, these fibers densely innervated the caudal part of the dorsomedial pallium, the hypothalamus, the thalamus, the mesencephalic tegmentum and the optic tectum. The distribution pattern of the FMRFamide-like immunoreactivity was compared with that reported in previous studies in other teleost species. The anatomical organization of the FMRFamide-like immunoreactive peptidergic system in the brain of Chionodraco hamatus suggests that a FMRFamide-like peptide may play a role as a neuromodulator in fish adapted to the extreme Antarctic environment.
Pestarino
M
M
Institute of Comparative Anatomy, University of Genova, Italy. pesta@igecuniv.csita.unige.it
Vallarino
M
M
D000818:Animals; D000864:Antarctic Regions; D000918:Antibody Specificity; D001923:Brain Chemistry; D004027:Diencephalon / Q000737:chemistry*; D019835:FMRFamide; D005260:Female; D005399:Fishes / Q000502:physiology*; D005455:Fluorescent Antibody Technique; D007150:Immunohistochemistry; D007447:Invertebrate Hormones / Q000032:analysis / Q000276:immunology; D008297:Male; D008636:Mesencephalon / Q000737:chemistry*; D009479:Neuropeptides / Q000032:analysis / Q000276:immunology*; D018377:Neurotransmitter Agents / Q000032:analysis / Q000276:immunology*
D007447:Invertebrate Hormones; D009479:Neuropeptides; D018377:Neurotransmitter Agents; D019835:FMRFamide