title: Lithiation-based silylation and stannylation of 6-chloro-9-(beta-D-ribofuranosyl)purine.
abstract: Reaction of the lithiated species of 9-(2,3,5-tris-O-tert-butyldimethylsilyl-beta-D-ribofuranosyl)-6-chloropu rine with Me3SiCl or Bu3SnCl was found to furnish the corresponding C-2 substituted product, as a result of silyl or stannyl migration from C-8 to C-2 position.
authors.affiliation: School of Pharmaceutical Sciences, Showa University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Katoh
authors.forename: H
authors.initials: H
authors.lastname: Hayakawa
authors.forename: H
authors.initials: H
authors.lastname: Tanaka
authors.forename: H
authors.initials: H
authors.lastname: Kumamoto
authors.forename: T
authors.initials: T
authors.lastname: Miyasaka
mesh_terms: D004563:Electrochemistry; D007202:Indicators and Reagents; D008094:Lithium / Q000737:chemistry; D008722:Methods; D015394:Molecular Structure; D011684:Purine Nucleosides / Q000138:chemical synthesis* / Q000737:chemistry*; D012825:Silicon / Q000737:chemistry; D014001:Tin / Q000737:chemistry
chemical_list: D007202:Indicators and Reagents; D011684:Purine Nucleosides; C024008:6-chloropurine riboside; D014001:Tin; D008094:Lithium; D012825:Silicon