Immune globulin treatment in intractable epilepsy of childhood.
Six children suffering from epilepsy refractory to conventional anti-convulsive therapy were treated with high-dose intravenous immune globulin (IVIG) (200 mg/kg three times per week, repeated after three weeks). In four children clinical and EEG findings markedly improved, while a partial response was noted in the other cases. These results suggest that high-dose intravenous immune globulin may have a beneficial effect in the treatment of intractable epilepsy.
Türkay
S
S
Department of Pediatrics, Cumhuriyet University Faculty of Medicine, Sivas.
Baskin
E
E
Dener
S
S
Gültekin
A
A
Tanzer
F
F
Sekreter
E
E
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D004829:Epilepsy, Generalized / Q000276:immunology / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D014421:Turkey
D016756:Immunoglobulins, Intravenous