title: [Spinal cord compression as the presenting form of non-Hodgkin's lymphoma].
abstract: Spinal cord compression as first presentation of non-Hodgkin's lymphoma (NHL) is an uncommon event. Diagnosis of NHL usually is performed on a laminectomy specimen. Spinal cord compression has been reported in 5% of patients with solid tumors. Although this clinical picture has been considered as very unusual among NHL patients, some series regarding descompresive laminectomy indicate that NHL was the underlying cause in 15% of these cases. We report two cases of patients with NHL who presented paraparesia secondary to spinal cord compression due to lymphomatous mass in the epidural region which was showed by magnetic resonance imaging. The emergency laminectomy and treatment with chemotherapy allowed the clinical recuperation of both patients.
authors.affiliation: Servicio de Hematología, Hospital Universitario de Salamanca.
authors.forename: M L
authors.initials: ML
authors.lastname: Amigo
authors.forename: R
authors.initials: R
authors.lastname: Revilla
authors.forename: C
authors.initials: C
authors.lastname: Sánchez
authors.forename: C
authors.initials: C
authors.lastname: del Cañizo
authors.forename: D
authors.initials: D
authors.lastname: Caballero
authors.forename: J F
authors.initials: JF
authors.lastname: San Miguel
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D004824:Epidural Space; D005047:Etoposide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007796:Laminectomy; D002955:Leucovorin / Q000008:administration & dosage; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D008466:Mechlorethamine / Q000008:administration & dosage; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D010291:Paresis / Q000209:etiology; D010292:Paresthesia / Q000209:etiology; D011241:Prednisone / Q000008:administration & dosage; D011344:Procarbazine / Q000008:administration & dosage; D012983:Soft Tissue Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D013117:Spinal Cord Compression / Q000209:etiology* / Q000601:surgery; D013125:Spinal Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D013899:Thoracic Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D013904:Thoracic Vertebrae; D016055:Urinary Retention / Q000209:etiology; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D011344:Procarbazine; D008466:Mechlorethamine; D014750:Vincristine; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D002955:Leucovorin; D011241:Prednisone; D008727:Methotrexate