title: Methodology for a randomised controlled trial of preschool vision screening. A new approach with the 'ALSPAC' project.
abstract: We present the methodology of a population-based Randomised Controlled Trial, comparing an intensive programme of primary preschool vision screening by orthoptists with the usual non-specialist screening. The aims of the trial are to compare the effectiveness and costs of intensive orthoptic screening with non-specialist measures. The orthoptic screening programme will be evaluated both as a composite package and in terms of the screening value of the individual tests at specific ages. This trial is nested within a large population-based longitudinal study. Additional demographic and developmental data on the children in the trial are therefore available. The results of the trial will be used to help clarify which methods of preschool ophthalmic population screening are best in terms of disease detection and cost efficiency.
authors.affiliation: Department of Ophthalmology, University of Bristol, England, U.K.
authors.forename: C
authors.initials: C
authors.lastname: Williams
authors.forename: R A
authors.initials: RA
authors.lastname: Harrad
authors.forename: I
authors.initials: I
authors.lastname: Harvey
authors.forename: S
authors.initials: S
authors.lastname: Frankel
authors.forename: J
authors.initials: J
authors.lastname: Golding
mesh_terms: D000550:Amblyopia / Q000175:diagnosis* / Q000191:economics; D002648:Child; D002675:Child, Preschool; D003152:Community Health Nursing / Q000191:economics; D003362:Cost-Benefit Analysis / Q000191:economics; D005194:Family Practice / Q000191:economics; D006302:Health Services Research / Q000379:methods*; D006801:Humans; D008137:Longitudinal Studies; D009988:Orthoptics / Q000191:economics; D013285:Strabismus / Q000175:diagnosis* / Q000191:economics; D006113:United Kingdom; D015351:Vision Screening / Q000191:economics*