[Cytolysins and homologous proteins produced by gram-negative bacteria. I. Hemolysis and leukotoxins of Escherichia coli, Bordetella pertussis, Pasteurella haemolytica and Actinobacillus sp].
Cytolysins produced by Gram-negative bacteria belong to the pore forming bacterial proteins. A branch of these toxins represents RTX family of proteins. The RTX (repeats in toxin) family name has been proposed based on the common presence of tandem copies of a nine-amino acid repeat (L-X-G-G-X-G-(N/D)-D-X). The paper presents the genetics, synthesis, secretion and cytolytic activity of these toxins.
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Zakład Mikrobiologii Ogólnej Instytutu Mikrobiologii i Immunologii Uniwersytetu Lódzkiego w Lodzi.
D000188:Actinobacillus / Q000378:metabolism; D001427:Bacterial Toxins / Q000096:biosynthesis*; D001886:Bordetella pertussis / Q000378:metabolism; D004926:Escherichia coli / Q000378:metabolism; D005098:Exotoxins / Q000096:biosynthesis*; D006090:Gram-Negative Bacteria / Q000378:metabolism*; D006460:Hemolysin Proteins / Q000096:biosynthesis*; D016978:Mannheimia haemolytica / Q000378:metabolism
D001427:Bacterial Toxins; D005098:Exotoxins; D006460:Hemolysin Proteins; C018579:leukotoxin