Pergolide treatment for Cushing's syndrome in a horse.
A 16-year-old, male, Hanoverian horse had a three-month history of weight loss, hirsutism and polyuria/polydypsia. Examinations revealed neutrophilia, lymphopenia, hyper glycaemia and abnormalities in hepatic function. A tentative diagnosis of hyperadrenocorticism was made. The results of thyroid-releasing hormone and combined dexamethasone suppression and ACTH stimulation tests suggested the presence of a pituitary adenoma. The horse was treated with pergolide and beneficial clinical and biochemical responses were observed within one to six months.
Muñoz
M C
MC
Departamento de Patología Animal, Facultad de Veterinaria, Universidad de Las Palmas de Gran Canaria, Spain.
Doreste
F
F
Ferrer
O
O
González
J
J
Montoya
J A
JA
D000818:Animals; D003480:Cushing Syndrome / Q000188:drug therapy / Q000662:veterinary*; D018491:Dopamine Agonists / Q000627:therapeutic use*; D006734:Horse Diseases / Q000188:drug therapy*; D006736:Horses; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D010479:Pergolide / Q000627:therapeutic use*
D018491:Dopamine Agonists; D010479:Pergolide; D006854:Hydrocortisone