A new aneurysm wrapping material: polyglactin 910 + fibrin sealant.
Aneurysms experimentally induced by using the silver nitrate coagulation method in 10 Wistar Albino rats are wrapped with Polyglactin 910 and Fibrin Sealant. 6 weeks later the rats are sacrificed and compared with the control group. In the group in which Polyglactin 910 and Fibrin Sealant were used as the wrapping material, non-specific inflammatory granulation tissue development around the aneurysms is observed. We suggest that a Polyglactin 910 and Fibrin Sealant combination can be used as a wrapping material in the treatment of aneurysms where clipping is not possible.
Uzan
M
M
Department of Neurosurgery, Medical Faculty, Istanbul University Cerrahapasa, Turkey.
Hanci
M
M
Kuday
C
C
Akar
Z
Z
Shamsi
A A
AA
Ozlen
F
F
Oz
B
B
Deniz
E
E
D000818:Animals; D002339:Carotid Arteries / Q000473:pathology; D004547:Elastic Tissue / Q000473:pathology; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage*; D006097:Granulation Tissue / Q000473:pathology; D002532:Intracranial Aneurysm / Q000473:pathology / Q000601:surgery*; D011098:Polyglactin 910; D051381:Rats; D017208:Rats, Wistar; D017539:Tunica Intima / Q000473:pathology
D015718:Fibrin Tissue Adhesive; D011098:Polyglactin 910