title: Novel tetranucleotide repeat polymorphism in the human adenosine deaminase gene: interethnic comparison of three major human groups.
abstract: A new tetranucleotide repeat polymorphism was revealed at the human adenosine deaminase (ADA) locus by using the polymerase chain reaction and denaturing polyacrylamide gel electrophoresis. Allele frequencies were estimated in seven populations from three major ethnic groups. Heterozygosity values were calculated and found to differ significantly between Africans and non-Africans.
authors.affiliation: Dipartimento di Genetica e Biologia Molecolare, Università La Sapienza, Rome, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Scozzari
authors.forename: F
authors.initials: F
authors.lastname: Cruciani
authors.forename: P
authors.initials: P
authors.lastname: Santolamazza
authors.forename: E
authors.initials: E
authors.lastname: Parra
authors.forename: D
authors.initials: D
authors.lastname: Sellitto
authors.forename: D
authors.initials: D
authors.lastname: Modiano
authors.forename: G
authors.initials: G
authors.lastname: Meloni
authors.forename: W
authors.initials: W
authors.lastname: Cai
authors.forename: P
authors.initials: P
authors.lastname: Moral
mesh_terms: D000243:Adenosine Deaminase / Q000032:analysis / Q000235:genetics*; D001483:Base Sequence; D005006:Ethnicity / Q000235:genetics*; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic / Q000235:genetics*; D011153:Population
chemical_list: D000243:Adenosine Deaminase