title: Ventricular fibrillation induction using nonsynchronized low energy external shock during rapid ventricular pacing: method of induction when fibrillation mode of ICD fails.
abstract: Third-generation implantable cardioverter defibrillators (ICD) are frequently implanted with nonthoracotomy systems and provide noninvasive methods for electrical stimulation and ventricular fibrillation induction. These modalities facilitate postoperative testing of the ICD. Rapid right ventricular burst pacing via the defibrillator is commonly used for initiation of ventricular tachyarrhythmias. However, with the available third-generation devices, ventricular fibrillation (VF) induction may be impossible in up to 19% of the patients. In these cases, transvenous placement of a right ventricular catheter has been required to generate VF and appropriately evaluate the device. We report a new technique of noninvasive induction of VF using a low energy external nonsynchronized shock delivered during ICD fibrillation induction pacing. In three patients, after all efforts to induce VF by the Ventritex Cadence V-100 had failed, a 20 J nonsynchronized shock was delivered during rapid RV pacing. This resulted in VF on the first attempt in all patients. This noninvasive technique of VF initiation may provide a useful clinical approach to ICD testing that eliminates the costs and risks of an invasive procedure.
authors.affiliation: Division of Cardiology, Electrophysiology Section, University of North Carolina, Chapel Hill 27599-7075, USA.
authors.forename: W E
authors.initials: WE
authors.lastname: Sanders
authors.forename: G L
authors.initials: GL
authors.lastname: Hamrick
authors.forename: M C
authors.initials: MC
authors.lastname: Herbst
authors.forename: W E
authors.initials: WE
authors.lastname: Cascio
authors.forename: R J
authors.initials: RJ
authors.lastname: Simpson
authors.forename: J M
authors.initials: JM
authors.lastname: Wharton
mesh_terms: D000328:Adult; D000368:Aged; D006328:Cardiac Catheterization; D002304:Cardiac Pacing, Artificial / Q000379:methods*; D017147:Defibrillators, Implantable; D004558:Electric Stimulation; D004867:Equipment Design; D005260:Female; D006801:Humans; D008297:Male; D014693:Ventricular Fibrillation / Q000209:etiology* / Q000628:therapy