Renal transplantation in cats with chronic renal failure.
Renal transplantation was performed on 6 cats with chronic renal failure. Clinical signs and the blood chemistry findings (BUN, Cr, IP) improved one week after renal transplantation. Renal anemia also improved 3-4 weeks after surgery. Two cases had the same complications, hydronephrosis and hydroureter within 1 or 2 weeks of surgery, evidenced by marked elevations of BUN and Cr, suggesting that ureteral obstruction at the site of ureterocystostomy is the main complication of renal transplantation in cats. As a new resolution for this problem, we transplanted the ureter with the intact ureteral opening of the bladder from the donor in the remaining 4 cats. Ureteral obstruction was not observed in them, thus the procedure was considered to be useful for avoiding this complication. Two cats died of pneumonia and other complications within 3 months. There were no acute rejections or side effects from the immunosuppressant during the observation period in the remaining four cats.
Mishina
M
M
Department of Surgery, School of Veterinary Medicine, Azabu University, Kanagawa, Japan.
Watanabe
T
T
Maeda
H
H
Fujii
K
K
Wakao
Y
Y
Takahashi
M
M
Ejima
H
H
D000818:Animals; D001806:Blood Urea Nitrogen; D002371:Cat Diseases; D002415:Cats; D003404:Creatinine / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D007165:Immunosuppression Therapy / Q000662:veterinary; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007676:Kidney Failure, Chronic / Q000601:surgery / Q000662:veterinary*; D016030:Kidney Transplantation / Q000379:methods / Q000502:physiology / Q000662:veterinary*; D008297:Male
D007166:Immunosuppressive Agents; D003404:Creatinine