Report of an intrapulmonary solitary fibrous tumor: fine-needle aspiration cytologic findings, clinicopathological, and immunohistochemical features.
The authors describe a rare case of intrapulmonary solitary fibrous tumor (SFT). Morphologically, the tumor showed a disorganized or "patternless" arrangement of plump to spindle cells in a collagenous stroma. Tumor cells were immunoreactive for vimentin, but not for keratin, carcinoembryonic antigen, epithelial membrane antigen, factor-VIII related antigen, S-100 protein, desmin, and actin. These immunohistochemical findings suggested fibroblastic differentiation, in keeping with the putative submesothelial origin of the tumor. The problems concerning the fine-needle aspiration (FNA) preoperative diagnosis of SFT are briefly discussed.
Caruso
R A
RA
Department of Human Pathology, University of Messina, Italy.
LaSpada
F
F
Gaeta
M
M
Minutoli
I
I
Inferrera
C
C
D000368:Aged; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D005350:Fibroma / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D010997:Pleural Neoplasms / Q000473:pathology