title: [Rubella and pregnancy: fetal infection without embryonal or fetal pathology. A case report].
abstract: A case of foetal infection with rubella virus during the 12th week of pregnancy, with an alpha-interferon level under 2IU after 24 weeks pregnancy was followed by normal birth. Clinical and radiological examinations at birth were unable to detect any signs of congenital rubella. When the infant was 8 months old, neurological examinations were normal and there was no sign of deafness. Foetal infection does not [correction of no] necessarily mean foetal disease. Medical abortion is only indicated in case of maternal rubella occurring before 11 weeks of pregnancy. After this date, the fear of deafness can be mitigated by the lack of viral replication proven by a low alpha interferon level.
authors.affiliation: Service de Gynécologie-Obstétrique, Centre Hospitalier Général de Saint-Pierre-Le Tampon, Saint-Pierre.
authors.forename: J
authors.initials: J
authors.lastname: Chapeau
authors.forename: A
authors.initials: A
authors.lastname: Fourmaintraux
mesh_terms: D000032:Abortion, Therapeutic; D000328:Adult; D003638:Deafness / Q000821:virology*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D016898:Interferon-alpha / Q000097:blood; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000821:virology*; D011261:Pregnancy Trimester, First; D011296:Prenatal Diagnosis; D012409:Rubella / Q000150:complications / Q000175:diagnosis*
chemical_list: D016898:Interferon-alpha