Torsade de pointes occurring early during oral amiodarone treatment.
Amiodarone is reported to have a low incidence of proarrhythmic effects. They generally occur during chronic treatment in association with increase in amiodarone dosage, electrolyte disorders, or concomitant therapy with class IA antiarrhythmic drugs. We describe a case of amiodarone-induced torsade de pointes early after initiation of low-dose oral therapy, in absence of other predisposing factors.
Faggiano
P
P
Gardini
A
A
D'Aloia
A
A
Benedini
G
G
Giordano
A
A
D000638:Amiodarone / Q000008:administration & dosage / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000009:adverse effects*; D015984:Causality; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008875:Middle Aged; D016171:Torsades de Pointes / Q000139:chemically induced*
D000889:Anti-Arrhythmia Agents; D000638:Amiodarone