title: Synaptic behaviour of sex chromosome in two XYY men.
abstract: Analysis of meiotic pairing behavior in two XYY males presenting at subfertility clinic brings evidence that the abnormal mode of pairing caused by the presence of the extra Y chromosome, disturbs achievement of spermatogenesis resulting in severe oligoastheno-teratozoospermia. In contrast, the loss of the supernumerary Y before meiosis, allows achievement and normal sperm production.
authors.affiliation: Institut d'Embryologie, ULP-Faculté de Médecine, Strasbourg, France.
authors.forename: O
authors.initials: O
authors.lastname: Gabriel-Robez
authors.forename: B
authors.initials: B
authors.lastname: Delobel
authors.forename: M F
authors.initials: MF
authors.lastname: Croquette
authors.forename: J M
authors.initials: JM
authors.lastname: Rigot
authors.forename: R
authors.initials: R
authors.lastname: Djlelati
authors.forename: Y
authors.initials: Y
authors.lastname: Rumpler
mesh_terms: D000328:Adult; D006801:Humans; D007248:Infertility, Male / Q000235:genetics; D008297:Male; D008540:Meiosis; D009845:Oligospermia / Q000235:genetics; D013091:Spermatogenesis; D014960:X Chromosome / Q000502:physiology*; D014997:XYY Karyotype / Q000235:genetics*; D014998:Y Chromosome / Q000502:physiology*