title: Correlation between CSWS and aphasia in Landau-Kleffner syndrome: a study of three cases.
abstract: We report three typical cases of Landau-Kleffner syndrome with varied courses. The very frequent discharges in sleep EEGs, often showing the patterns of CSWS (continuous spike-waves during slow-wave sleep), either typical (spike-wave complex occupying over 85% of slow-wave sleep duration) or atypical (spike-waves occupying less than 85% of slow-wave sleep), were presented in all our cases. The CSWS seems correlated with aphasia in our cases. Since the disappearance of CSWS might be indicative of a lagged improvement in aphasia, we suggest that sufficiently long-term treatment with anticonvulsants and/or corticosteroids is worthwhile, if the EEG is improved significantly by this treatment.
authors.affiliation: Department of Pediatrics, First Hospital, Beijing Medical University, China.
authors.forename: M
authors.initials: M
authors.lastname: Li
authors.forename: X Y
authors.initials: XY
authors.lastname: Hao
authors.forename: J
authors.initials: J
authors.lastname: Qing
authors.forename: X R
authors.initials: XR
authors.lastname: Wu
mesh_terms: D000927:Anticonvulsants / Q000008:administration & dosage; D002675:Child, Preschool; D004569:Electroencephalography; D006801:Humans; D018887:Landau-Kleffner Syndrome / Q000188:drug therapy / Q000503:physiopathology*; D008297:Male; D012894:Sleep Stages / Q000502:physiology*
chemical_list: D000927:Anticonvulsants