Expression of virulence-related properties by, and intestinal adhesiveness of, Vibrio mimicus strains isolated from aquatic environments.
A study of the major pathogenic characteristics of Vibrio mimicus was carried out with 77 strains isolated from aquatic environments in Okayama, Japan. Of the strains tested, 96% demonstrated in vitro adherence to the rabbit intestinal mucosa, of which 36, 20, and 43% belonged to the strongly, moderately, and weakly adhesive groups, respectively. Of the 27 strains which appeared to be enterotoxigenic in the experiments using rabbit ileal loops, 74% belonged to the strongly adhesive group. All strains of V. mimicus at early log phase showed cell-mediated hemagglutination, and 70% of strongly hemagglutinative strains belonged to the strongly adhesive group, implying a possible correlation between cell-mediated hemagglutination and bacterial adherence. However, no significant correlation could be detected in the production of putative exocellular pathogenic factors and bacterial adherence or enterotoxigenicity.
Alam
M
M
Faculty of Pharmaceutical Sciences, Okayama University, Japan.
Miyoshi
S
S
Yamamoto
S
S
Tomochika
K
K
Shinoda
S
S
D000818:Animals; D001422:Bacterial Adhesion / Q000502:physiology*; D010450:Endopeptidases / Q000096:biosynthesis; D006384:Hemagglutination; D006460:Hemolysin Proteins / Q000096:biosynthesis; D006877:Hydroxamic Acids / Q000378:metabolism; D007082:Ileum / Q000382:microbiology; D007413:Intestinal Mucosa / Q000382:microbiology*; D007564:Japan; D011817:Rabbits; D017262:Siderophores / Q000096:biosynthesis; D014733:Vibrio / Q000378:metabolism / Q000472:pathogenicity*; D014774:Virulence; D014871:Water Microbiology
D006460:Hemolysin Proteins; D006877:Hydroxamic Acids; D017262:Siderophores; C031819:aerobactin; D010450:Endopeptidases