title: Some immunological parameters in workers occupationally exposed to n-hexane.
abstract: 1. To estimate the quantitative relation between exposure to airborne n-hexane and various markers of immune function, 35 male workers were examined and compared with unexposed controls. 2. Urinary 2,5-hexanedione concentrations were significantly higher in the exposed group than in the unexposed. 3. A significant suppression was observed in the serum immunoglobulin (IgG, IgM and IgA) levels between two populations. Also, a significant correlation was found between urinary 2,5-hexanedione concentrations and serum Ig level of the exposed group. 4. No significant difference between white blood cell counts was found in the two groups.
authors.affiliation: Department of Toxicology, Ankara University, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Karakaya
authors.forename: B
authors.initials: B
authors.lastname: Yücesoy
authors.forename: S
authors.initials: S
authors.lastname: Burgaz
authors.forename: H U
authors.initials: HU
authors.lastname: Sabir
authors.forename: A E
authors.initials: AE
authors.lastname: Karakaya
mesh_terms: D000269:Adhesives; D000328:Adult; D000367:Age Factors; D005260:Female; D006586:Hexanes / Q000097:blood / Q000633:toxicity* / Q000652:urine; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis*; D007958:Leukocyte Count / Q000187:drug effects*; D008297:Male; D016273:Occupational Exposure / Q000009:adverse effects* / Q000032:analysis
chemical_list: D000269:Adhesives; D006586:Hexanes; D007136:Immunoglobulins; C026385:n-hexane