Use of recombinant tissue-type plasminogen activator to treat massive pulmonary embolism after cesarean section: a case report.
A 30-year-old primigravida, delivering by cesarean section, went into shock with cardiac arrest due to pulmonary thromboembolism. Thrombolytic therapy with recombinant-tissue-type plasminogen activator (rt-PA) induced a rapid improvement in both the hemodynamic and respiratory conditions. This case shows the marked efficacy of rt-PA in treating massive pulmonary thromboembolism. Close attention must be given to the patient in such a case, however, because the risk of hemorrhagic complication exists.
Onoyama
Y
Y
Department of Obstetrics and Gynecology, Shimonoseki City Hospital, Japan.
Minamitani
M
M
Takeuchi
H
H
Sakai
S
S
Eguchi
H
H
D000328:Adult; D002585:Cesarean Section; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D011183:Postoperative Complications; D011247:Pregnancy; D011644:Puerperal Disorders / Q000188:drug therapy*; D011655:Pulmonary Embolism / Q000188:drug therapy*; D011994:Recombinant Proteins / Q000627:therapeutic use; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator