title: Helicobacter pylori: current concepts.
abstract: Although first described almost a century ago, only in the last 15 years has Helicobacter pylori been characterized and associations with disease states recognized. H pylori has been linked to both gastritis and peptic ulcer disease. There is also evidence for a relationship with non-Hodgkin's lymphoma, mucosa-associated lymphoid tissue lymphoma, and perhaps even adenocarcinoma of the stomach. There is currently insufficient evidence to link H pylori to nonulcer dyspepsia. Current recommendations are to treat all patients with gastric or duodenal ulcers who test positive for H pylori, as therapy will significantly reduce the recurrence rate of these conditions.
authors.affiliation: Northeastern Ohio Universities College of Medicine in Canton.
authors.forename: G
authors.initials: G
authors.lastname: Neff
authors.forename: M M
authors.initials: MM
authors.lastname: Van Ness
authors.forename: D F
authors.initials: DF
authors.lastname: Dies
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005770:Gastrointestinal Neoplasms / Q000382:microbiology; D016481:Helicobacter Infections / Q000175:diagnosis / Q000188:drug therapy; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D010437:Peptic Ulcer / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents