title: Merkel cell tumor in a woman with chronic lymphocytic leukemia.
abstract: We describe a 69-year-old woman with basal cell carcinoma, and chronic lymphocytic leukemia who developed Merkel cell tumor. This latter malignancy first appeared as enlarged lymph nodes in the axilla and elbow regions and responded initially to radiotherapy. Later, the patient developed obstructive jaundice which was due to pancreatic metastases of the Merkel cell tumor, documented by post-mortem examination. To our knowledge, this is the first description of a Merkel cell tumor causing obstructive jaundice, in a patient with chronic lymphocytic leukemia.
authors.affiliation: Hebrew University Medical School, Jerusalem, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Safadi
authors.forename: O
authors.initials: O
authors.lastname: Pappo
authors.forename: E
authors.initials: E
authors.lastname: Okon
authors.forename: S
authors.initials: S
authors.lastname: Sviri
authors.forename: A
authors.initials: A
authors.lastname: Eldor
mesh_terms: D000368:Aged; D001365:Axilla; D002280:Basal Cell Carcinoma; D015266:Carcinoma, Merkel Cell / Q000150:complications / Q000532:radiotherapy / Q000556:secondary; D001651:Cholestasis, Extrahepatic / Q000209:etiology / Q000601:surgery; D003137:Common Bile Duct Diseases / Q000209:etiology / Q000601:surgery; D004550:Elbow; D004927:Escherichia coli Infections / Q000209:etiology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell; D009378:Neoplasms, Multiple Primary; D010190:Pancreatic Neoplasms / Q000556:secondary; D011183:Postoperative Complications / Q000209:etiology; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology / Q000532:radiotherapy