Immunomodulation in transplantation with photopheresis.
Photopheresis is a technique in which peripheral blood mononuclear cells, in the presence of a photoactivatable compound, are exposed extracorporeally to ultraviolet A light and reinfused, inducing a host autoregulatory immune response. Experimental work and ongoing clinical studies are helping to define the role of this novel, safe, and non-toxic immunomodulating technology in the field of transplantation.
Barr
M L
ML
Division of Cardiothoracic Surgery, University of Southern California, Los Angeles 90033-4612, USA.
D000818:Animals; D006087:Graft vs Host Reaction / Q000528:radiation effects*; D016027:Heart Transplantation / Q000009:adverse effects; D006801:Humans; D007165:Immunosuppression Therapy; D007963:Leukocytes, Mononuclear / Q000166:cytology / Q000528:radiation effects; D016040:Lung Transplantation / Q000009:adverse effects; D016377:Organ Transplantation / Q000009:adverse effects*; D017893:Photopheresis; D014184:Transplantation, Homologous; D014467:Ultraviolet Therapy / Q000592:standards*