title: Epithelioid sarcoma of the spine: a case report.
abstract: METHODS
  This case report illustrates a patient presenting with sciatica and diagnosed with epithelioid sarcoma involving the spine.
  
  
  OBJECTIVE
  The treatment of this patient involved multiple mass resections and decompressions of the spinal canal. Radio- and chemotherapy were applied once a clear diagnosis was obtained.
  
  
  BACKGROUND
  Epithelioid sarcoma is a rare tumor mainly arising in the extremities. Confusion with a benign inflammatory process are possible. Treatment after histologic diagnosis involves wide resection. To our knowledge, this report represents the first case of epithelioid sarcoma involving the spine.
  
  
  METHODS
  After initial discectomy, recurrent scarring and mass formation required multiple decompression procedures and fusion. The initial pathology revealed inflammatory reaction on fibrosis. In a later procedure, the histologic diagnosis of epithelioid sarcoma was made. Radiotherapy and chemotherapy were begun immediately.
  
  
  RESULTS
  Despite aggressive resections, radiotherapy, and chemotherapy, the patient died 3 months after the last surgical procedure.
  
  
  CONCLUSIONS
  Spinal epithelioid sarcoma can be mistaken for a benign inflammatory process. After a histologic diagnosis, aggressive wide resection is necessary. Multiple recurrences are documented with this tumor in other sites. Prognosis in trunk involvement is less favorable than involvement of the extremities. The role of adjuvant radio- and chemotherapy is unclear for spinal involvement.
authors.affiliation: Spine Unit, Hospital Stephanie, Strasbourg, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Steib
authors.forename: F
authors.initials: F
authors.lastname: Pierchon
authors.forename: J P
authors.initials: JP
authors.lastname: Farcy
authors.forename: G
authors.initials: G
authors.lastname: Lang
authors.forename: D
authors.initials: D
authors.lastname: Christmann
authors.forename: J P
authors.initials: JP
authors.lastname: Gnassia
mesh_terms: D000328:Adult; D004576:Electromyography; D006801:Humans; D007633:Keratins / Q000032:analysis / Q000276:immunology; D008279:Magnetic Resonance Imaging; D008297:Male; D012086:Reoperation; D012447:Sacrum / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D012509:Sarcoma / Q000175:diagnosis* / Q000601:surgery; D012585:Sciatica / Q000209:etiology; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D044465:White People
chemical_list: D007633:Keratins