title: Superimposition of In-111 platelet SPECT and CT/MR imaging in intracardiac thrombus.
abstract: An initial attempt to superimpose in-111-labeled platelet SPECT over CT/MRI in two patients with intracardiac thrombus is presented. One patient was a 65-year-old woman with a history of mitral and tricuspid valve replacement. This patient had a large thrombus measuring 74 x 43 x 34 mm in the right atrium. Fusion imaging with CT showed increased in-111 activity on the surface of the thrombus, which was visualized as circular activity on a planar image. The other patient was a 72-year-old woman who had a thrombus measuring 17 x 14 x 12 mm at the cardiac apex. Planar imaging showed two discrete areas of abnormal in-111 activity. Superimposition of the SPECT image over MR revealed that one of these areas corresponded to the small thrombus, whereas the other related to a previous subendomyocardial biopsy. In both patients, the activity ratio of the abnormal in-111 accumulation versus the cardiac chamber on SPECT was greater than that on planar images. The correlation of in-111 platelet SPECT and CT/MRI was useful in accurately localizing the intracardiac thrombus.
authors.affiliation: Department of Radiology, Yamaguchi University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Suga
authors.forename: K
authors.initials: K
authors.lastname: Nishigauchi
authors.forename: N
authors.initials: N
authors.lastname: Kume
authors.forename: G
authors.initials: G
authors.lastname: Miura
authors.forename: K
authors.initials: K
authors.lastname: Takano
authors.forename: S
authors.initials: S
authors.lastname: Koike
authors.forename: N
authors.initials: N
authors.lastname: Matsunaga
authors.forename: T
authors.initials: T
authors.lastname: Fujii
authors.forename: M
authors.initials: M
authors.lastname: Matsuzaki
mesh_terms: D000368:Aged; D004912:Erythrocytes; D005260:Female; D006325:Heart Atria / Q000000981:diagnostic imaging / Q000473:pathology; D006331:Heart Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging*; D006350:Heart Valve Prosthesis; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007091:Image Processing, Computer-Assisted; D007205:Indium Radioisotopes; D008279:Magnetic Resonance Imaging; D008943:Mitral Valve; D013927:Thrombosis / Q000175:diagnosis / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed; D014261:Tricuspid Valve
chemical_list: D007205:Indium Radioisotopes