title: Allele distribution of a VNTR polymorphism at D4S43 locus in the Japanese population.
abstract: Allele frequencies for the VNTR locus D4S43 were determined in a Japanese population sample by the polymerase chain reaction. Nine different alleles containing 1-15 repeats of the basic 14 bp unit were observed in 156 unrelated Japanese. The most common allele was one repeat unit (62.82%), and the next common alleles were those with 11 (14.42%) and 7 repeat units (12.50%). We estimated that D4S43 locus has a heterozygosity index of 0.56, a mean exclusion chance of 0.32, a discrimination rate of 0.76, and a polymorphic information content of 0.52. No evidence of significant deviations from the Hardy-Weinberg equillibrium was found in the Japanese population data.
authors.affiliation: Department of Legal Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Katsuyama
authors.forename: N
authors.initials: N
authors.lastname: Harashima
authors.forename: A
authors.initials: A
authors.lastname: Tsuchikane
authors.forename: M
authors.initials: M
authors.lastname: Ota
authors.forename: C
authors.initials: C
authors.lastname: Liu
authors.forename: H
authors.initials: H
authors.lastname: Zenda
authors.forename: H
authors.initials: H
authors.lastname: Fukushima
mesh_terms: D000483:Alleles; D001483:Base Sequence; D002874:Chromosome Mapping; D002894:Chromosomes, Human, Pair 4; D004247:DNA / Q000235:genetics; D005787:Gene Frequency; D006801:Humans; D007564:Japan; D018598:Minisatellite Repeats / Q000235:genetics*; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
chemical_list: D004247:DNA