title: Primary lymph node invasive aspergillosis.
abstract: A case of apparently primary lymph node granulomatous aspergillosis is described. A review of the so-called primary aspergillosis cases since 1977 shows that granulomatous instead of exudative inflammation patterns have been observed in histological sections only when neither major nor minor predisposing factors have been detected in the clinical history of the patients. A possible pathogenetic role of selectively impaired cell-mediated immune response in these cases is hypothesized. Flucytosine treatment is indicated in a few selected cases of deep aspergillosis.
authors.affiliation: Istituto di Microbiologia, Università di Bologna, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Mazzoni
authors.forename: M
authors.initials: M
authors.lastname: Ferrarese
authors.forename: R
authors.initials: R
authors.lastname: Manfredi
authors.forename: A
authors.initials: A
authors.lastname: Facchini
authors.forename: C
authors.initials: C
authors.lastname: Sturani
authors.forename: A
authors.initials: A
authors.lastname: Nanetti
mesh_terms: D000293:Adolescent; D000907:Antibodies, Bacterial / Q000097:blood; D001228:Aspergillosis / Q000276:immunology / Q000382:microbiology*; D001232:Aspergillus fumigatus / Q000276:immunology / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging; D008198:Lymph Nodes / Q000382:microbiology / Q000473:pathology*; D011859:Radiography
chemical_list: D000907:Antibodies, Bacterial