title: Application of near-infrared reflectance spectrometry to the analytical control of pharmaceuticals: ranitidine hydrochloride tablet production.
abstract: The possibility of applying near-infrared reflectance spectrometry to the control of the production cycle of ranitidine hydrochloride tablets was investigated. The results were good for the identification of ranitidine hydrochloride drug substance, mixtures for tablets, cores and coated tablets. The determination of the compound and of its water content also gave satisfactory results.
authors.affiliation: Dipartimento Farmaco Chimico Tecnologico, Siena, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Dreassi
authors.forename: G
authors.initials: G
authors.lastname: Ceramelli
authors.forename: P
authors.initials: P
authors.lastname: Corti
authors.forename: P L
authors.initials: PL
authors.lastname: Perruccio
authors.forename: S
authors.initials: S
authors.lastname: Lonardi
mesh_terms: D011899:Ranitidine / Q000032:analysis*; D013055:Spectrophotometry, Infrared; D013607:Tablets
chemical_list: D013607:Tablets; D011899:Ranitidine