title: Outcome of functioning filtering blebs after pars plana vitrectomy.
abstract: OBJECTIVE
  To determine the status of filtering bleb function following pars plana vitrectomy.
  
  
  METHODS
  The authors retrospectively reviewed patients with functioning filtering blebs undergoing pars plana vitrectomy.
  
  
  RESULTS
  Twenty-three eyes with functioning filtering blebs underwent pars plana vitrectomy. Postoperatively, 7/23 (30 percent) of the eyes had moderate (5 to 20 mm Hg) intraocular pressure (IOP), 8/23 of the eyes had IOP persistently greater than 20 mm Hg, and 7/23 of the eyes had IOP of less than 5 mm Hg. One of 7 eyes that underwent vitrectomy within 6 weeks after trabeculectomy maintained bleb function, whereas 6 of 16 eyes that underwent trabeculectomy 6 weeks or later maintained bleb function. Loss of bleb function occurred in the early postoperative period in the majority of the patients. Prior antimetabolite therapy was not associated with preservation of bleb function.
  
  
  CONCLUSIONS
  There is a substantial risk of bleb failure following vitrectomy, which is in part related to the often severe nature of the diseases requiring vitreoretinal surgery.
authors.affiliation: Bascom Palmer Eye Institute/Department of Ophthalmology, University of Miami School of Medicine, Miami, FL, USA.
authors.forename: W S
authors.initials: WS
authors.lastname: Thompson
authors.forename: W E
authors.initials: WE
authors.lastname: Smiddy
authors.forename: H W
authors.initials: HW
authors.lastname: Flynn
authors.forename: P E
authors.initials: PE
authors.lastname: Rubsamen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000503:physiopathology* / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014130:Trabeculectomy; D016896:Treatment Outcome; D014821:Vitrectomy / Q000009:adverse effects