title: Acebutolol overdose treated with hemodialysis and extracorporeal membrane oxygenation.
abstract: A case involving a 27-year-old woman who ingested an overdose of acebutolol is presented. Extracorporeal membrane oxygenation was initiated to stabilize the patient's condition before commencing hemodialysis. S-diacetolol (the N-acetelation product of acebutolol) was cleared with hemodialysis. It is suggested that extracorporeal membrane oxygenation may be of short-term benefit in the treatment of overdoses with beta-adrenergic agents such as acebutolol when accelerated clearance with hemodialysis is anticipated.
authors.affiliation: Department of Anaesthesia, University of Saskatchewan, Saskatoon, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Rooney
authors.forename: K L
authors.initials: KL
authors.lastname: Massey
authors.forename: F
authors.initials: F
authors.lastname: Jamali
authors.forename: M
authors.initials: M
authors.lastname: Rosin
authors.forename: D
authors.initials: D
authors.lastname: Thomson
authors.forename: D H
authors.initials: DH
authors.lastname: Johnson
mesh_terms: D000070:Acebutolol / Q000097:blood / Q000506:poisoning*; D000319:Adrenergic beta-Antagonists / Q000097:blood / Q000506:poisoning*; D000328:Adult; D062787:Drug Overdose / Q000628:therapy; D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006801:Humans; D006435:Renal Dialysis
chemical_list: D000319:Adrenergic beta-Antagonists; D000070:Acebutolol