The epidemiology of AIDS--related neoplasms.
The magnitude for and risk factors of the two most important AIDS neoplasm, Kaposi's sarcoma and non-Hodgkin's lymphoma, are reviewed in detail. The association between AIDS and other cancers is mostly speculative because surveillance biases tend to favor detecting associations that may be spurious. The overall relative risk of other cancers appears, however, to be only twofold above that in the general population, with associations being most convincing for anal (but not cervical) cancer and leiomyosarcoma and possible also for Hodgkin's disease, testicular cancer, and conjunctival cancers.
Biggar
R J
RJ
Viral Epidemiology Branch, National Cancer Institute, Bethesda, Maryland, USA.
Rabkin
C S
CS
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D001005:Anus Neoplasms / Q000453:epidemiology / Q000209:etiology; D002648:Child; D005260:Female; D006689:Hodgkin Disease / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D007890:Leiomyosarcoma / Q000453:epidemiology / Q000209:etiology; D016483:Lymphoma, AIDS-Related / Q000453:epidemiology / Q000209:etiology; D008228:Lymphoma, Non-Hodgkin / Q000453:epidemiology / Q000209:etiology; D008297:Male; D009369:Neoplasms / Q000453:epidemiology* / Q000209:etiology; D012514:Sarcoma, Kaposi / Q000453:epidemiology / Q000209:etiology; D014481:United States; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000209:etiology