title: Phosphorus nuclear magnetic resonance spectroscopy: in vivo magnesium measurements in the skeletal muscle of normal subjects.
abstract: 31P nuclear magnetic resonance spectroscopy was used to study the skeletal muscle of 33 normal males and 32 females. Free intracellular magnesium levels and the ratios of the phosphorus metabolites were determined. Males had significantly lower free magnesium levels (499.8 microM +/- 26.3 microM vs. 530.7 microM +/- 36.0 microM, P = 0.001, d.f. = 63, analysis of variance). The free magnesium level (rs = -0.5431, P = 0.001) and the phosphocreatin/Inorganic phosphate ratio in males (rs = -0.4102, P = 0.018), and the phosphocreatine/Inorganic phosphate ratio in females (rn = -0.4759, P = 0.009) fell with the increasing Minnesota Heart Health Program Questionnaire score.
authors.affiliation: Department of Physiology and Biophysics, School of Medicine, Georgetown University Medical Center, Washington, DC 20007, USA.
authors.forename: K M
authors.initials: KM
authors.lastname: Ward
authors.forename: S S
authors.initials: SS
authors.lastname: Rajan
authors.forename: M
authors.initials: M
authors.lastname: Wysong
authors.forename: D
authors.initials: D
authors.lastname: Radulovic
authors.forename: D J
authors.initials: DJ
authors.lastname: Clauw
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008274:Magnesium / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000378:metabolism*; D010758:Phosphorus; D012016:Reference Values
chemical_list: D010758:Phosphorus; D008274:Magnesium