Acyl-CoA transferase activities in homogenates of Fasciola hepatica adults.
Succinyl-CoA is an intermediate in the formation of the fermentation product, propionate, by Fasciola hepatica adults. Acyl-CoA transferase activities are present in crude homogenates of Fasciola, which could account for the synthesis of succinyl-CoA from succinate by the transfer of CoA from either propionyl-CoA or acetyl-CoA. No transferase activity was apparent from 2-methylbutyryl-CoA or 2-methylvaleryl-CoA as was previously reported for the nematode, Ascaris suum. Heat denaturation experiments indicate that all of the Fasciola transferase activities may result from a single protein.
Saz
H J
HJ
Department of Biological Sciences, University of Notre Dame, Indiana 46556, USA.
deBruyn
B
B
de Mata
Z
Z
D000818:Animals; D017165:Ascaris suum / Q000201:enzymology; D002851:Chromatography, High Pressure Liquid; D015256:Coenzyme A-Transferases / Q000032:analysis*; D005210:Fasciola hepatica / Q000201:enzymology*; D012588:Scintillation Counting
D015256:Coenzyme A-Transferases; C031212:acyl-CoA transferase