title: Clinical correlates of quantitative acoustic analysis in ataxic dysarthria.
abstract: The speech of 15 Taiwanese patients with cerebellar dysfunction and ataxic dysarthria was investigated utilizing techniques of acoustic analysis and instrumental measurement. Semiquantitative assessment of cerebellar function (SQACF) was also performed. The results of the acoustic analysis of the cerebellar speech were then correlated with the findings in the SQACF. The overlapping of voice onset time highly correlates with truncal ataxia as well as eye movement abnormality and eye-hand coordination. The prolongation of vowel duration also correlates significantly with tandem walking, dysdiadochokinesia and eye movement abnormality. The correlation of the speech function with other cerebellar motor functions provides further insight into the functional anatomy for cerebellar speech motor control. This study concludes that the midline structures-vermis and fastigial nucleus-seem to be the primary focus for the coordination of motor speech in the cerebellum.
authors.affiliation: Department of Neurology, National Taiwan University Hospital, College of Medicine, National Taiwan University, Taipei.
authors.forename: M J
authors.initials: MJ
authors.lastname: Chiu
authors.forename: R C
authors.initials: RC
authors.lastname: Chen
authors.forename: C Y
authors.initials: CY
authors.lastname: Tseng
mesh_terms: D000162:Acoustics; D001259:Ataxia / Q000503:physiopathology*; D002531:Cerebellum / Q000503:physiopathology; D004401:Dysarthria / Q000503:physiopathology*; D005133:Eye Movements; D006801:Humans; D011597:Psychomotor Performance; D013060:Speech; D016138:Walking