Parasympathetic activity in Friedrich's ataxia.
We compared 19 patients with Friedreich's ataxia, a progressive hereditary neuromuscular disorder, with 19 healthy age-matched subjects. During nighttime, patients had shorter mean RR and decreased heart rate variability parameters related to parasympathetic activity than healthy subjects, whereas no difference occurred during daytime.
Pousset
F
F
Department of Cardiology, Pitié-Saltpêtrière Hospital, Paris, France.
Kalotka
H
H
Durr
A
A
Isnard
R
R
Lechat
P
P
Le Heuzey
J Y
JY
Thomas
D
D
Komajda
M
M
D000328:Adult; D018880:Atrial Premature Complexes / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology; D004452:Echocardiography; D005260:Female; D005583:Fourier Analysis; D005621:Friedreich Ataxia / Q000150:complications / Q000503:physiopathology*; D006339:Heart Rate / Q000502:physiology*; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010275:Parasympathetic Nervous System / Q000503:physiopathology*