title: Antibiotic-associated colitis in orthopaedic patients.
abstract: Antibiotic-associated colitis was diagnosed in 23 orthopaedic patients: 17 had abdominal symptoms, 3 had a fever and the remaining 3 had no symptoms but increasing C-reactive protein values or white blood count. The antibiotic was clindamycin in 19, cephalosporins in 3 and a combination of vancomycin and fusidic acid intravenously in one. The antibiotics were stopped in 12, changed in 5 and continued in the remaining 5. Oral treatment for colitis was given in 21 patients, and in one patient the only treatment was stopping the antibiotics. One patient died after a myocardial infarct; the remaining 22 were discharged after successful treatment of their primary condition and the colitis.
authors.affiliation: Orthopaedic Hospital Vienna-Speising, Vienna, Austria.
authors.forename: M
authors.initials: M
authors.lastname: Boehler
authors.forename: T
authors.initials: T
authors.lastname: Rustler
authors.forename: D
authors.initials: D
authors.lastname: Wolf
authors.forename: K
authors.initials: K
authors.lastname: Knahr
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001847:Bone Diseases / Q000150:complications / Q000188:drug therapy; D003092:Colitis / Q000139:chemically induced* / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D018461:Soft Tissue Infections / Q000150:complications / Q000188:drug therapy; D013203:Staphylococcal Infections / Q000150:complications / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents