title: Drug-induced Parkinsonism associated with dysphagia and aspiration: a brief report.
abstract: Idiopathic Parkinsonism is a well-recognized cause of dysphagia and resultant aspiration. Symptoms and signs attributable to dopaminergic underactivity after administration of antipsychotic medication are commonly seen in elderly patients. We report a case of a 74-year-old woman, without prior symptoms of Parkinsonism or dysphagia, who presented with the temporal association of both after administration of trifluoperazine hydrochloride. Dysphagia is a potentially life-threatening complication of drug-induced parkinsonism. Its early recognition allows treatment by simple medical, physical, and dietary manipulations.
authors.affiliation: Department of Rehabilitation & Geriatrics, Illawarra Regional Hospital, Warrawong NSW, Australia.
authors.forename: G
authors.initials: G
authors.lastname: Bashford
authors.forename: P
authors.initials: P
authors.lastname: Bradd
mesh_terms: D000368:Aged; D003680:Deglutition Disorders / Q000139:chemically induced* / Q000175:diagnosis; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D009460:Neurologic Examination / Q000187:drug effects; D010302:Parkinson Disease, Secondary / Q000139:chemically induced* / Q000175:diagnosis; D011015:Pneumonia, Aspiration / Q000139:chemically induced* / Q000175:diagnosis; D011618:Psychotic Disorders / Q000188:drug therapy* / Q000523:psychology; D014268:Trifluoperazine / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D014268:Trifluoperazine