title: The spectrum of herpes simplex virus disease of the anterior segment in the 1990s.
abstract: We have sampled our clinic population in order to ascertain the proportion with herpetic eye disease of the anterior segment. The age, gender predominance, and incidence of bilateral disease amongst such patients has not changed over the past 20 years. The predominant disease type was stromal keratitis, with significant morbidity and visual handicap. Herpetic eye disease of the anterior segment utilizes only 1% of out-patient clinic resources overall, but 17% of specialist external disease clinic time. There was a statistically significant correlation between total length of follow-up and reduced visual acuity. It would seem that the prevalence of herpetic eye disease of the anterior segment appears to have halved since comparable reports were published. In addition, the prognosis of the disease, in terms of the prevalence of visual impairment, has worsened.
authors.affiliation: Cornea & External Disease Service, Moorfields Eye Hospital, London, UK.
authors.forename: C
authors.initials: C
authors.lastname: Claoué
authors.forename: R
authors.initials: R
authors.lastname: De Cock
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000869:Anterior Eye Segment / Q000187:drug effects / Q000821:virology*; D000998:Antiviral Agents / Q000627:therapeutic use; D005260:Female; D006295:Health Resources / Q000706:statistics & numerical data; D018259:Herpesvirus 1, Human / Q000472:pathogenicity*; D006801:Humans; D015994:Incidence; D016849:Keratitis, Herpetic / Q000188:drug therapy / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D011795:Surveys and Questionnaires; D006113:United Kingdom / Q000453:epidemiology; D014792:Visual Acuity
chemical_list: D000998:Antiviral Agents