title: Pathological definitions and characteristics of stage T1 prostate cancer.
abstract: The American Joint Committee on Cancer (AJCC) defines T1 prostate cancers as clinically inapparent tumors not palpable or visible by imaging. Given the use of serum prostate-specific antigen (PSA), more of these incidental carcinomas are being detected by needle biopsy as part of a work-up for an increased PSA. However, the pathological characteristics and the biological potential of these tumors are quite variable. This chapter summarizes some of the recent literature describing pathobiological features of T1 tumors, their subclassification, and the problems encountered in diagnosing these carcinomas.
authors.affiliation: Department of Anatomic Pathology, University of California, San Francisco School of Medicine, USA.
authors.forename: V
authors.initials: V
authors.lastname: Bhargava
mesh_terms: D001706:Biopsy; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D017430:Prostate-Specific Antigen / Q000097:blood*; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000097:blood / Q000473:pathology* / Q000601:surgery
chemical_list: D017430:Prostate-Specific Antigen