Retinal vein occlusion after trabeculectomy with mitomycin C.
OBJECTIVE
To evaluate acute retinal vein occlusion as a potential complication of trabeculectomy with mitomycin C in cases of advanced glaucoma.


METHODS
The records of three patients who developed retinal vein occlusions immediately after uncomplicated trabeculectomy with mitomycin C were reviewed.


RESULTS
All three patients had advanced open-angle glaucoma with total cupping of the optic nerve, severe visual field loss, and evidence of systemic vascular disease. A marked decrease in intraocular pressure was noted in the postoperative period in all of the patients.


CONCLUSIONS
A shift in the lamina cribrosa, associated with the perioperative intraocular pressure change, may have contributed to occlusion of the venous outflow system in these susceptible patients.
Dev
S
S
Department of Ophthalmology, Duke University, USA.
Herndon
L
L
Shields
M B
MB
D000368:Aged; D000369:Aged, 80 and over; D005902:Glaucoma, Open-Angle / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D016685:Mitomycin / Q000008:administration & dosage / Q000009:adverse effects*; D011183:Postoperative Complications / Q000139:chemically induced; D012170:Retinal Vein Occlusion / Q000139:chemically induced*; D014130:Trabeculectomy / Q000009:adverse effects*; D014792:Visual Acuity
D016685:Mitomycin