Major clinical trials assessing the prophylactic use of amiodarone in patients with ventricular tachyarrhythmias.
The purpose of this article is to summarize and critique recently completed and ongoing clinical trials assessing the prophylactic use of amiodarone in patients with potentially life-threatening ventricular arrhythmias. Three of the trials compare amiodarone with an implantable cardioverter defibrillator.
Fogoros
R N
RN
Department of Medicine, Medical College of Pennsylvania, Allegheny General Hospital, Pittsburgh 15212, USA.
D000638:Amiodarone / Q000627:therapeutic use*; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D016757:Death, Sudden, Cardiac / Q000517:prevention & control*; D017147:Defibrillators, Implantable; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy; D016032:Randomized Controlled Trials as Topic; D013223:Statistics as Topic; D017180:Tachycardia, Ventricular / Q000188:drug therapy / Q000401:mortality / Q000517:prevention & control*
D000889:Anti-Arrhythmia Agents; D000638:Amiodarone