title: Pupillary response to topical tropicamide as a marker for Alzheimer's disease.
abstract: The mydriatic response to eyedrops of the anticholinergic drug tropicamide at very low concentration (0.01%) was studied in subjects with Alzheimer's disease (AD, n = 10) and multi-infarct dementia (MID, n = 10). There was no significant difference in pupillary response between the two groups. The test is unlikely to be useful in differentiating different types of dementia.
authors.affiliation: Division of Psychiatry, United Medical and Dental Schools (Guy's), Bexley Hospital, Kent, UK.
authors.forename: A J
authors.initials: AJ
authors.lastname: Treloar
authors.forename: M
authors.initials: M
authors.lastname: Assin
authors.forename: A J
authors.initials: AJ
authors.lastname: Macdonald
mesh_terms: D000287:Administration, Topical; D000368:Aged; D000544:Alzheimer Disease / Q000503:physiopathology*; D006801:Humans; D011680:Pupil / Q000187:drug effects*; D014331:Tropicamide / Q000008:administration & dosage*
chemical_list: D014331:Tropicamide