Plasma levels of gamma-aminobutyric acid and panic disorder.
Low levels of gamma-aminobutyric acid (GABA) in plasma have been associated with the presence of mood disorders in patients with major depressive disorder. We examined plasma GABA in patients with panic disorder, a disorder that is often comorbid with major depression, and in a group of control subjects. Patients with panic disorder had plasma GABA levels that did not differ significantly from levels in controls subjects. These data support the specificity of low plasma GABA as a marker for mood disorders.
Goddard
A W
AW
Department of Psychiatry, Yale University School of Medicine, Connecticut Mental Health Center, New Haven 06519, USA.
Narayan
M
M
Woods
S W
SW
Germine
M
M
Kramer
G L
GL
Davis
L L
LL
Petty
F
F
D000328:Adult; D000379:Agoraphobia / Q000097:blood / Q000150:complications; D001008:Anxiety Disorders / Q000097:blood / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000097:blood / Q000150:complications; D016584:Panic Disorder / Q000097:blood* / Q000150:complications; D010949:Plasma; D005680:gamma-Aminobutyric Acid / Q000097:blood*
D005680:gamma-Aminobutyric Acid