title: The post-investigation questionnaire (PIO-R): a practical instrument to assess erectile response after intracavernous injection.
abstract: Erectile response to intracavernous pharmacological stimulation is highly susceptible to stress and anxiety provoked by the test-situation. To reduce false-positive diagnosis of veno-occlusive dysfunction and to limit the need for high-dosage pharmacotesting, we developed the Post-Investigation Questionnaire (PIQ-R), a self-report instrument to assess erectile response to pharmacological stimulation after the patient has left the office. In this study veno-occlusive sufficiency was not demonstrated in 80 of 105 patients with erectile dysfunction at the time of pharmaco-penile duplex ultrasonography. PIQ-R detected sufficient erectile response in 40 of these patients, thus reducing false-positive diagnosis of veno-occlusive dysfunction by 50%. We also found that reports of sexual activity after investigation increased interest in auto-injection therapy. PIQ-R is a practical self-report measure to assess erectile response after clinical pharmacotesting, and to more carefully select patients for auto-injection therapy.
authors.affiliation: Department of Urology, University Hospital Nijmegen, The Netherlands. p.vruggink@uro.azn.nl
authors.forename: P A
authors.initials: PA
authors.lastname: Vruggink
authors.forename: W L
authors.initials: WL
authors.lastname: Diemont
authors.forename: E J
authors.initials: EJ
authors.lastname: Meuleman
mesh_terms: D007172:Erectile Dysfunction / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology*; D005189:False Positive Reactions; D006801:Humans; D018783:Impotence, Vasculogenic / Q000000981:diagnostic imaging; D007267:Injections; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000008:administration & dosage* / Q000627:therapeutic use; D010410:Penile Erection / Q000187:drug effects*; D010413:Penis / Q000000981:diagnostic imaging; D012725:Sexual Behavior / Q000187:drug effects; D011795:Surveys and Questionnaires; D014463:Ultrasonography; D014665:Vasodilator Agents / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D014665:Vasodilator Agents; D010208:Papaverine