title: Hematologic disorders and growth factor support in HIV infection.
abstract: During the course of HIV disease a broad spectrum of hematologic disorders develop including abnormalities in blood cell generation, survival, and function Alterations in coagulation parameters may evolve associated with disruption of immunoglobulin or factor production. This article reviews the manifestations and pathophysiology of these abnormalities and discusses the role for growth factor support.
authors.affiliation: Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: D T
authors.initials: DT
authors.lastname: Scadden
mesh_terms: D001778:Blood Coagulation Disorders / Q000188:drug therapy / Q000209:etiology; D004921:Erythropoietin / Q000502:physiology / Q000627:therapeutic use; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000502:physiology / Q000627:therapeutic use; D006133:Growth Substances / Q000502:physiology / Q000627:therapeutic use*; D015658:HIV Infections / Q000150:complications*; D006402:Hematologic Diseases / Q000188:drug therapy / Q000209:etiology*; D006801:Humans; D008231:Lymphopenia / Q000188:drug therapy / Q000209:etiology
chemical_list: D006133:Growth Substances; D004921:Erythropoietin; D016178:Granulocyte-Macrophage Colony-Stimulating Factor