title: Paper electrophoresis in the study of mixed ligand complexes in solution. The system Fe(III)- and Cr(III)-methyl cysteine-penicillamine.
abstract: A method involving use of paper electrophoresis is described for the study of equilibria in mixed ligand [methyl cysteine-penicillamine] complex systems in solution. The concentration of the primary ligand methyl cysteine was kept constant, while that of secondary ligand penicillamine was varied. The plots of -log [penicillamine] against mobility were used to obtain information on the formation of mixed complex and to calculate its stability constants. The binary equilibria M(III)-methyl cysteine have also been studied since this is a pre-requisite for the investigation of mixed complexes. The stability constants of [Fe(III)- methyl cysteine-penicillamine] and [Cr(III)-methyl cysteine-penicillamine] complexes were found to be 7.40 +/- 0.13 and 4.80 +/- 0.07 (log K values) for Fe(III) and Cr(III) complexes, respectively, at mu = 0.1 mol/L and at a temperature of 35 degrees C.
authors.affiliation: Department of Chemistry, University of Roorkee, India.
authors.forename: B B
authors.initials: BB
authors.lastname: Tewari
mesh_terms: D002614:Chelating Agents / Q000737:chemistry*; D002857:Chromium / Q000737:chemistry*; D003545:Cysteine / Q000031:analogs & derivatives* / Q000737:chemistry; D004590:Electrophoresis, Paper / Q000379:methods; D005100:Expectorants / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D008024:Ligands; D010396:Penicillamine / Q000737:chemistry*
chemical_list: D002614:Chelating Agents; D005100:Expectorants; D005290:Ferric Compounds; D008024:Ligands; D002857:Chromium; D010396:Penicillamine; D003545:Cysteine; C017507:mecysteine