title: Baclofen for chronic hiccups.
abstract: Chronic hiccups is a rare occurrence but can be debilitating for the patient. Successful intervention is seldom reported. The present case is a young adult who had severe almost continuous hiccups for 3 years after placement of a feeding gastrostomy and Nissen fundoplication. Within weeks of initiation of baclofen treatment, the hiccups ceased. Recurrences of hiccups have responded to increases in baclofen dosage.
authors.affiliation: Department of Pediatrics, Gillette Children's Hospital and Health Partners, St. Paul/Minneapolis, Minnesota, USA.
authors.forename: B R
authors.initials: BR
authors.lastname: Johnson
authors.forename: R L
authors.initials: RL
authors.lastname: Kriel
mesh_terms: D000293:Adolescent; D001418:Baclofen / Q000627:therapeutic use*; D001720:Birth Injuries / Q000150:complications; D001925:Brain Damage, Chronic / Q000150:complications; D001933:Brain Stem / Q000503:physiopathology; D018662:Fundoplication / Q000009:adverse effects; D005774:Gastrostomy / Q000009:adverse effects; D006606:Hiccup / Q000188:drug therapy* / Q000209:etiology; D006801:Humans; D006849:Hydrocephalus / Q000150:complications; D008297:Male; D009125:Muscle Relaxants, Central / Q000627:therapeutic use*
chemical_list: D009125:Muscle Relaxants, Central; D001418:Baclofen