title: Left ventricular functions are not impaired after lumbar epidural anaesthesia in young children.
abstract: We studied the haemodynamic and cardiovascular effects of epidural anaesthesia with plain bupivacaine 0.75 ml.kg-1 in 13 unpremedicated ASA 1 children using measurements of heart rate, blood pressure and M-mode echocardiography. Under general anaesthesia, M-mode echocardiographic evaluation of left ventricular function in each patient was performed at four points (after general anaesthesia, point A; 5 min, 10 min and 25 min after epidural anaesthesia, point B; point C; and point D, respectively). Results were compared between point A and B, A and C, A and D, B and C, B and D, C and D. HR decreased significantly at 10 min (point C) and 25 min (point D) and MBP decreased at 5 min (point B) and 10 min (point D) compared to point A. No other M-mode cardiographic indices were changed at any point. Epidural anaesthesia using 0.25% bupivacaine 0.75 ml.kg-1 did not affect LV function in young children.
authors.affiliation: Department of Anaesthesiology, Mitsui Memorial Hospital, Tokyo, Japan.
authors.forename: M H
authors.initials: MH
authors.lastname: Tsuji
authors.forename: H
authors.initials: H
authors.lastname: Horigome
authors.forename: M
authors.initials: M
authors.lastname: Yamashita
mesh_terms: D000767:Anesthesia, Epidural; D000779:Anesthetics, Local / Q000494:pharmacology; D001794:Blood Pressure / Q000187:drug effects; D002045:Bupivacaine / Q000494:pharmacology; D002675:Child, Preschool; D004452:Echocardiography; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D016277:Ventricular Function, Left
chemical_list: D000779:Anesthetics, Local; D002045:Bupivacaine