title: Normal values for pentachlorophenol in urine samples collected from a general population.
abstract: Aliquots of urine samples collected over a 24-h period from normal individuals were analyzed for pentachlorophenol (PCP). Urine samples were taken from subjects living in various regions (both rural and urban) throughout the province of Saskatchewan. Urinary PCP concentrations were determined with gas chromatography-mass spectrometry and stable isotope dilution. The normal PCP concentrations were found to range from 0.05 to 3.6 ng/mliters. Because the aliquots analyzed were taken from 24-h sample collections, the normal range of PCP excreted on a daily basis was determined. A total of 69 samples taken from 26 males and 43 females who ranged in age from 6 to 87 years were analyzed. The average amount of excreted PCP was determined to be 4.3 nmol/day.
authors.affiliation: Saskatchewan Health, Laboratory & Disease Control Services Branch, Regina, Canada.
authors.forename: R G
authors.initials: RG
authors.lastname: Treble
authors.forename: T S
authors.initials: TS
authors.lastname: Thompson
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D004781:Environmental Exposure; D004785:Environmental Pollutants / Q000493:pharmacokinetics* / Q000652:urine; D005260:Female; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D010416:Pentachlorophenol / Q000493:pharmacokinetics* / Q000652:urine; D012016:Reference Values; D012525:Saskatchewan
chemical_list: D004785:Environmental Pollutants; D010416:Pentachlorophenol