title: Establishment of an in vitro cell derived from human angiosarcoma.
abstract: We have succeeded in the establishment of a human endothelial cell line derived from a human angiosarcoma. These cells grew as monolayers with a "cobble stone" morphology. The cells produced endothelin and showed Weibel-Palade bodies in their cytoplasm. These findings show that the cells have specific differenciated functions, and might be useful for both fundamental endothelial cell biology and biological investigation of angiosarcoma.
authors.affiliation: Service de dermatologie, höpitaux universitaires de la ville d'Osaka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Hisa
authors.forename: S
authors.initials: S
authors.lastname: Taniguchi
authors.forename: K
authors.initials: K
authors.lastname: Kakudo
authors.forename: M
authors.initials: M
authors.lastname: Ichihashi
authors.forename: T
authors.initials: T
authors.lastname: Takashima
authors.forename: Y
authors.initials: Y
authors.lastname: Kato
authors.forename: R
authors.initials: R
authors.lastname: Hayakawa
authors.forename: M
authors.initials: M
authors.lastname: Takigawa
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016232:Endothelins / Q000032:analysis; D004730:Endothelium, Vascular / Q000473:pathology; D005260:Female; D006394:Hemangiosarcoma / Q000473:pathology*; D006801:Humans; D066298:In Vitro Techniques; D008113:Liver Neoplasms / Q000473:pathology*; D014407:Tumor Cells, Cultured
chemical_list: D016232:Endothelins