[The metabolism of glucose and lipids in patients with liver disease undergoing upper abdominal operation and the influence of the difference of intraoperative fluids].
To clarify the change of glucose and lipids metabolism in patients with liver disease undergoing upper abdominal operation, we examined the serum level of glucose, total ketone body, free fatty acid and l-lactate. At the end of the operation, 1-lactate level increased and total ketone body level elevation was suppressed as the bleeding increased. Also in patients undergoing hepatectomy, total ketone body level elevation was suppressed. From these results, we concluded that gluconeogenesis and utilization of fatty acid in the liver were augmented. These metabolic changes were not different between the group infused with lactated Ringer and the group infused with acetated Ringer.
Kabutan
K
K
Department of Anesthesiology, National Okayama Hospital.
Satou
K
K
Ono
J
J
Sugimoto
S
S
Morimoto
N
N
Taniguchi
M
M
D000005:Abdomen / Q000601:surgery; D000368:Aged; D000767:Anesthesia, Epidural; D000769:Anesthesia, Inhalation; D001786:Blood Glucose / Q000378:metabolism*; D005260:Female; D006801:Humans; D007430:Intraoperative Care; D007552:Isotonic Solutions / Q000008:administration & dosage / Q000494:pharmacology*; D007657:Ketone Bodies / Q000378:metabolism; D050356:Lipid Metabolism; D008103:Liver Cirrhosis / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D000077325:Ringer's Lactate
D001786:Blood Glucose; D007552:Isotonic Solutions; D007657:Ketone Bodies; D000077325:Ringer's Lactate