title: Carcinoma arising in ectopic hamartomatous thymoma. An ultrastructural study.
abstract: We present the ultrastructural features of a case of adenocarcinoma arising in ectopic hamartomatous thymoma in a 31 year old man, in the supraclavicular location. The tumor had a cribriform adenomatous component with a granular cell quality and mimicked a metastatic carcinoma. Ultrastructurally, the spindle cell component revealed clusters of tonofilaments and the tumor cells were attached by well developed desmosomes. The cytoplasm of adenocarcinoma cells contained peculiar cup-shaped bodies derived from the endoplasmic reticulum wrapped around the mitochondria.
authors.affiliation: Sikls Department of Pathology, Medical Faculty, Charles University, Pilsen, Czech Republic.
authors.forename: M
authors.initials: M
authors.lastname: Michal
authors.forename: L
authors.initials: L
authors.lastname: Neubauer
authors.forename: F
authors.initials: F
authors.lastname: Fakan
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology / Q000648:ultrastructure*; D000328:Adult; D006222:Hamartoma / Q000473:pathology; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology / Q000648:ultrastructure*; D013896:Thoracic Diseases / Q000473:pathology; D013899:Thoracic Neoplasms / Q000473:pathology / Q000648:ultrastructure*; D013945:Thymoma / Q000473:pathology / Q000648:ultrastructure*