title: Flavor and the frontal cortex.
abstract: Rats were trained to discriminate an aqueous compound of an odor and taste (amyl acetate and NaCl) from the components of the compound before removal of one olfactory bulb and the contralateral ventrolateral frontal cortex. In postoperative tests, experimental rats performed much more poorly than nonlesioned controls or controls which had all lesions made in the same hemisphere. However, there were no significant differences among groups on tests for detection of amyl acetate and NaCl. These results provide evidence that integration of taste and smell in the production of flavor occurs in the ventrolateral frontal cortex.
authors.affiliation: Department of Neurobiology, Weizmann Institute of Science, Rehovot, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Schul
authors.forename: B M
authors.initials: BM
authors.lastname: Slotnick
authors.forename: Y
authors.initials: Y
authors.lastname: Dudai
mesh_terms: D000818:Animals; D001931:Brain Mapping; D004193:Discrimination Learning / Q000502:physiology*; D004292:Dominance, Cerebral / Q000502:physiology; D005518:Food Preferences / Q000502:physiology; D005625:Frontal Lobe / Q000502:physiology*; D008297:Male; D009830:Olfactory Bulb / Q000502:physiology*; D009833:Olfactory Pathways / Q000502:physiology; D000439:Pentanols; D051381:Rats; D017208:Rats, Wistar; D012903:Smell / Q000502:physiology*; D017673:Sodium Chloride, Dietary; D013649:Taste / Q000502:physiology*
chemical_list: D000439:Pentanols; D017673:Sodium Chloride, Dietary; C005716:amyl acetate