title: Exposure of Danish children to traffic exhaust fumes.
abstract: This exposure study addresses the validity of the exposure assessment method of an epidemiological study of traffic-related air pollution and childhood cancer. In particular, this paper concerns the question of whether the concentration of nitrogen dioxide (NO2) outside the front door is a valid marker of the exposure of the child living at the address. The study includes 100 children living on streets with dense traffic in central parts of Copenhagen and 100 children living in rural areas. Preliminary results, based on 25% of the study subjects, suggest that both the outdoor NO2-concentration and the exposure of the children are two to three times higher in Copenhagen than in the rural districts. Moreover, the results suggest that the NO2-concentration outside the front door is a poor marker of the exposure of the children in Copenhagen, but a marker of some relevance for the exposure of the children in rural districts. The preliminary results must be treated with caution, as among other things, the analysis did not consider seasonal changes and indoor NO2-sources such as passive smoking, candles, and gas appliances.
authors.affiliation: Danish Cancer Society, Division for Cancer Epidemiology, Copenhagen O, Denmark.
authors.forename: O
authors.initials: O
authors.lastname: Raaschou-Nielsen
authors.forename: J H
authors.initials: JH
authors.lastname: Olsen
authors.forename: O
authors.initials: O
authors.lastname: Hertel
authors.forename: R
authors.initials: R
authors.lastname: Berkowicz
authors.forename: H
authors.initials: H
authors.lastname: Skov
authors.forename: A M
authors.initials: AM
authors.lastname: Hansen
authors.forename: C
authors.initials: C
authors.lastname: Lohse
mesh_terms: D000393:Air Pollutants / Q000009:adverse effects / Q000032:analysis*; D000397:Air Pollution / Q000009:adverse effects / Q000032:analysis*; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003718:Denmark / Q000453:epidemiology; D004781:Environmental Exposure / Q000009:adverse effects / Q000032:analysis*; D006801:Humans; D009369:Neoplasms / Q000453:epidemiology / Q000209:etiology; D009585:Nitrogen Dioxide / Q000009:adverse effects / Q000032:analysis*; D018570:Risk Assessment; D012424:Rural Population; D014505:Urban Population; D001335:Vehicle Emissions / Q000009:adverse effects / Q000032:analysis*
chemical_list: D000393:Air Pollutants; D001335:Vehicle Emissions; D009585:Nitrogen Dioxide