title: Databases of mRNA untranslated regions for metazoa.
abstract: The important role that untranslated regions of mRNAs (UTR) may play in gene regulation and expression is now widely accepted. For this reason we developed UTRDB, a specialized database of 5'- and 3'-UTR of eukaryotic mRNAs cleaned of redundancy. This paper describes the composition and the general feature of UTRDB. The analysis of UTRDB by using suitable statistical methods could provide useful information for guiding the experimental work aimed at delucidating the role of UTR sequences in gene regulation and expression.
authors.affiliation: Dipartimento di Biochimica e Biologia Molecolare, Universitá di Bari and CSMME-CNR, Italy. Pesole/mvx36.csata.it
authors.forename: G
authors.initials: G
authors.lastname: Pesole
authors.forename: G
authors.initials: G
authors.lastname: Grillo
authors.forename: S
authors.initials: S
authors.lastname: Liuni
mesh_terms: D000465:Algorithms; D000818:Animals; D005786:Gene Expression Regulation / Q000235:genetics; D016045:Human Genome Project; D007256:Information Systems; D014176:Protein Biosynthesis / Q000235:genetics*; D012333:RNA, Messenger / Q000737:chemistry* / Q000235:genetics; D017421:Sequence Analysis; D012984:Software
chemical_list: D012333:RNA, Messenger