The life and times of an intestinal M cell.
Intestinal M cells are specialized epithelial antigen-sampling cells, strategically located over mucosal lymphoid follicles. They regulate the entry of antigen required for mucosal immune responses. There are several potential mechanisms involved in the induction of intestinal M cells. Both luminal antigen and B cells appear to have an influence on these altered epithelial differentiation pathways.
Savidge
T C
TC
Dept of Cellular Physiology, Babraham Institute, Cambridge, UK. SavidgeT@bbsrc.ac.uk
D000818:Animals; D017951:Antigen Presentation; D002450:Cell Communication; D002454:Cell Differentiation; D002477:Cells / Q000145:classification; D007413:Intestinal Mucosa / Q000166:cytology* / Q000276:immunology*; D008214:Lymphocytes / Q000276:immunology; D008221:Lymphoid Tissue / Q000166:cytology* / Q000276:immunology*; D051379:Mice; D016513:Mice, SCID; D010641:Phenotype