title: Coronary physiology of percutaneous rotational atherectomy.
abstract: Integration of coronary blood flow velocity measurements into interventional procedures has enhanced our understanding of coronary flow dynamics. The coronary physiology of rotational atherectomy, with and without adjunctive coronary angioplasty, has not been well-defined. This review describes the coronary physiology induced by rotational atherectomy. Serial coronary blood flow and translesional hemodynamics, measured following rotational atherectomy and again after adjunctive balloon angioplasty, indicate that coronary blood flow and flow reserve may not be normalized despite significant angiographic improvements after rotational atherectomy alone and after adjunctive balloon angioplasty.
authors.affiliation: Department of Internal Medicine, Division of Cardiology, St. Louis University Health Sciences Center, MO 63110, USA.
authors.forename: A
authors.initials: A
authors.lastname: Khoury
authors.forename: M J
authors.initials: MJ
authors.lastname: Kern
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary; D000818:Animals; D017225:Atherectomy, Coronary; D001783:Blood Flow Velocity; D017023:Coronary Angiography; D003326:Coronary Circulation; D003327:Coronary Disease / Q000503:physiopathology / Q000601:surgery*; D003331:Coronary Vessels / Q000000981:diagnostic imaging; D006801:Humans; D008297:Male; D018084:Ultrasonography, Interventional