Effect of fungistatic agent 2-deoxy-D-glucose on mycotoxins from Penicillium expansum.
Mycotoxin production from Penicillium expansum was effected by the 'biocontrol enhancer' 2-deoxy-D-glucose (DOG). Citrinin and gentisyl alcohol were produced in higher amounts, whereas patulin was inhibited, which represents a differential effect on the polyketide metabolic pathway. These effects have implications for the use of DOG in biocontrol.
Abo-Dahab
N F
NF
International Mycological Institute, Egham, Surrey, UK.
Paterson
R R
RR
Razak
A A
AA
D000963:Antimetabolites / Q000494:pharmacology*; D001592:Benzyl Alcohols / Q000378:metabolism; D002953:Citrinin / Q000378:metabolism; D003847:Deoxyglucose / Q000494:pharmacology*; D009183:Mycotoxins / Q000378:metabolism*; D010365:Patulin / Q000378:metabolism; D010407:Penicillium / Q000187:drug effects*
D000963:Antimetabolites; D001592:Benzyl Alcohols; D009183:Mycotoxins; D002953:Citrinin; D010365:Patulin; D003847:Deoxyglucose; C004771:2,5-dihydroxybenzyl alcohol