title: Experimental study of alleviation of hypertension, diabetes and pain by radon inhalation.
abstract: Indications for treatment at the Misasa Hot Spring, a radon producing radioactive spring, include hypertension, diabetes mellitus and pain. To clarify its mechanisms of action on these conditions, we evaluated dynamic changes in blood components such as vasoactive substances after radon inhalation. Vasodilation, alleviation of diabetic symptoms and morphine-like analgesic effects were observed, suggesting that these changes constitute part of the mechanisms of the radon spring therapy on the above conditions.
authors.affiliation: Radiation Safety Group Central Research Institute of Electric Power Industry, Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Yamaoka
authors.forename: Y
authors.initials: Y
authors.lastname: Komoto
mesh_terms: D000280:Administration, Inhalation; D000818:Animals; D001918:Brachytherapy; D003921:Diabetes Mellitus, Experimental / Q000628:therapy*; D004744:Enkephalin, Methionine / Q000097:blood; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006973:Hypertension / Q000628:therapy*; D009479:Neuropeptides / Q000097:blood; D059408:Pain Management; D011817:Rabbits; D011886:Radon / Q000008:administration & dosage / Q000627:therapeutic use*; D014664:Vasodilation / Q000187:drug effects; D001615:beta-Endorphin / Q000097:blood
chemical_list: D009479:Neuropeptides; D004744:Enkephalin, Methionine; D001615:beta-Endorphin; D005954:Glucosephosphate Dehydrogenase; D011886:Radon