title: An evaluation of the effects of susceptibility changes on the water chemical shift method of temperature measurement in human peripheral muscle.
abstract: Divergencies between chemical shift measurements of temperature and directly measured values using optical sensors have been studied in vivo in human peripheral muscle with the assistance of a variety of experimental and theoretical techniques. These include the modelling of both thermal and susceptibility changes using two- and three-dimensional finite element methods, as well as the use of multi-wavelength near-infrared observations. The conclusion of these studies is that a simple temperature calibration is not accessible, with results affected by the complex response of the tissue itself.
authors.affiliation: Robert Steiner MRI Unit, Hammersmith Hospital, London, United Kingdom.
authors.forename: I R
authors.initials: IR
authors.lastname: Young
authors.forename: J V
authors.initials: JV
authors.lastname: Hajnal
authors.forename: I G
authors.initials: IG
authors.lastname: Roberts
authors.forename: J X
authors.initials: JX
authors.lastname: Ling
authors.forename: R J
authors.initials: RJ
authors.lastname: Hill-Cottingham
authors.forename: A
authors.initials: A
authors.lastname: Oatridge
authors.forename: J A
authors.initials: JA
authors.lastname: Wilson
mesh_terms: D006801:Humans; D008961:Models, Structural; D009132:Muscles / Q000378:metabolism*; D019265:Spectroscopy, Near-Infrared; D013696:Temperature; D014867:Water / Q000737:chemistry*
chemical_list: D014867:Water