Rhinoreactivity in a patient affected by the Darier-White disease.
The Darier-White disease is a rare hyperkeratosic skin-disease which can also affect other organs. From an otoiatric point or view, there are alterations of the oral cavity, salivary glands and congenital deafness, but there is nothing against the nasal mucosa. The clinical case we studied, shows the presence of aspecific nasal hyperreactivity correlated to sun exposure as it happens for cutaneous lesions, independently of the presence of eosinophiles in the nasal secretion. This could mean that the Darler-White disease can also alter the function of the nasal mucosa.
Zambetti
G
G
Institute of Otorhinolaryngology, University of Rome La Sapienza.
Luce
M
M
Lo Vecchio
A
A
Filiaci
F
F
D000402:Airway Obstruction / Q000150:complications; D000403:Airway Resistance; D007644:Darier Disease / Q000150:complications*; D004802:Eosinophilia / Q000209:etiology; D005260:Female; D006358:Hot Temperature / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D009297:Nasal Mucosa / Q000378:metabolism / Q000473:pathology; D009299:Nasal Provocation Tests; D012130:Respiratory Hypersensitivity / Q000209:etiology*; D013472:Sunlight / Q000009:adverse effects*; D014887:Weather