title: Acyl-CoA transferase activities in homogenates of Fasciola hepatica adults.
abstract: Succinyl-CoA is an intermediate in the formation of the fermentation product, propionate, by Fasciola hepatica adults. Acyl-CoA transferase activities are present in crude homogenates of Fasciola, which could account for the synthesis of succinyl-CoA from succinate by the transfer of CoA from either propionyl-CoA or acetyl-CoA. No transferase activity was apparent from 2-methylbutyryl-CoA or 2-methylvaleryl-CoA as was previously reported for the nematode, Ascaris suum. Heat denaturation experiments indicate that all of the Fasciola transferase activities may result from a single protein.
authors.affiliation: Department of Biological Sciences, University of Notre Dame, Indiana 46556, USA.
authors.forename: H J
authors.initials: HJ
authors.lastname: Saz
authors.forename: B
authors.initials: B
authors.lastname: deBruyn
authors.forename: Z
authors.initials: Z
authors.lastname: de Mata
mesh_terms: D000818:Animals; D017165:Ascaris suum / Q000201:enzymology; D002851:Chromatography, High Pressure Liquid; D015256:Coenzyme A-Transferases / Q000032:analysis*; D005210:Fasciola hepatica / Q000201:enzymology*; D012588:Scintillation Counting
chemical_list: D015256:Coenzyme A-Transferases; C031212:acyl-CoA transferase