title: Acrodermatitis continua of Hallopeau: response to combined treatment with acitretin and calcipotriol ointment.
abstract: Treatment of acrodermatitis continua of Hallopeau (ACH) is difficult and often disappointing. We describe a patient with an extensive ACH of all finger- and toetips, who was treated with acitretin combined with calcipotriol. A within-subject left/right comparison was carried out between calcipotriol ointment (50 micrograms/g) and the ointment base to investigate the additional value of calcipotriol above the ointment base. The side treated with calcipotriol as adjunct therapy showed an impressive improvement, well beyond the degree of improvement at the side treated with the ointment base only.
authors.affiliation: Department of Dermatology, University Hospital Nijmegen, The Netherlands.
authors.forename: A L
authors.initials: AL
authors.lastname: Kuijpers
authors.forename: R J
authors.initials: RJ
authors.lastname: van Dooren-Greebe
authors.forename: P C
authors.initials: PC
authors.lastname: van de Kerkhof
mesh_terms: D017255:Acitretin / Q000627:therapeutic use*; D000169:Acrodermatitis / Q000188:drug therapy* / Q000276:immunology; D000368:Aged; D002117:Calcitriol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D009504:Neutrophils / Q000187:drug effects; D009824:Ointments
chemical_list: D003879:Dermatologic Agents; D009824:Ointments; C055085:calcipotriene; D002117:Calcitriol; D017255:Acitretin