title: Funguria in cancer patients: analysis of risk factors, clinical presentation and outcome in 50 patients.
abstract: Fifty cancer patients with funguria of > 10(5) CFU/ml, dysuria and leukocyturia were retrospectively analyzed for etiology, risk factors and outcome. In 72% of cases Candida albicans and in 28% non-albicans Candida spp. (Candida krusei, Candida tropicalis) and non-Candida spp. yeasts (Blastoschizomyces capitatus) were isolated. Torulopsis glabrata was not found among these patients. The most frequent risk factors were: antibiotic therapy with more than one antibiotic agent (96%), concomitant fungal infection in other localizations than the urinary tract (36%), colonization with the same species (48%), catheterization with urinary catheter or nephrostomy (46%), prophylaxis with quinolones (50%) and previous therapy with corticosteroids (72%). Structural or anatomic malformations of the urinary tract (26%), neutropenia (28%), antifungal prophylaxis with azoles (22%), and diabetes mellitus (12%) were less frequently seen. Thirty of 36 patients treated with systemic antifungals were cured and six were not.
authors.affiliation: Dept. of Medicine, University of Trnava, Slovak Republic.
authors.forename: E
authors.initials: E
authors.lastname: Oravcova
authors.forename: J
authors.initials: J
authors.lastname: Lacka
authors.forename: L
authors.initials: L
authors.lastname: Drgona
authors.forename: M
authors.initials: M
authors.lastname: Studena
authors.forename: L
authors.initials: L
authors.lastname: Sevcikova
authors.forename: S
authors.initials: S
authors.lastname: Spanik
authors.forename: J
authors.initials: J
authors.lastname: Svec
authors.forename: E
authors.initials: E
authors.lastname: Kukuckova
authors.forename: E
authors.initials: E
authors.lastname: Grey
authors.forename: J
authors.initials: J
authors.lastname: Silva
authors.forename: V
authors.initials: V
authors.lastname: Krcméry
mesh_terms: D001759:Blastomycosis / Q000150:complications / Q000382:microbiology* / Q000503:physiopathology; D002175:Candida / Q000302:isolation & purification*; D002176:Candida albicans / Q000302:isolation & purification*; D002177:Candidiasis / Q000150:complications / Q000382:microbiology* / Q000503:physiopathology; D006801:Humans; D009369:Neoplasms / Q000150:complications / Q000382:microbiology* / Q000503:physiopathology; D009894:Opportunistic Infections / Q000150:complications / Q000382:microbiology* / Q000503:physiopathology; D012189:Retrospective Studies; D012307:Risk Factors