title: Application of the method of spectral-statistical analysis EMG for evaluating the influence of medication on the treatment of Parkinson's disease.
abstract: The results of using of the new method analysis EMG in the evaluation of the influence of single pharmacological tests (PhT) for Parkinson's disease are described in this article. PhT applied for investigation of the group 41 patients diagnosed with Parkinson's disease of different etiologies, forms and stages. The study was carried out before taking the medicine and 40-60 minutes after taking the medicine. Patients were prescribed a single, habitual, individualized doses of anti-Parkinson's medicine. Analysis of the materials show that in the PhT, in 23% of the cases, for the group of muscles under study change in the tremor frequency in the direction of normality was observed. In 2% of the cases, reduction in the magnitude of tremor was observed. In 10% of the cases, both frequency and magnitude of tremors were registered. In 65% of the cases, no change what soever was indicated. For those patients for which the effectiveness of the medicine was manifested independently in certain groups of muscles, corrective medical therapy was recommended.
authors.affiliation: Russian Academy of Sciences, Clinical Neurology Department, Russian Academy of Postgraduate Medical Education, Moscow, Russia.
authors.forename: O Y
authors.initials: OY
authors.lastname: Khutorskaya
authors.forename: N V
authors.initials: NV
authors.lastname: Fjodorova
mesh_terms: D000328:Adult; D000368:Aged; D004576:Electromyography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology; D010300:Parkinson Disease / Q000188:drug therapy* / Q000503:physiopathology*; D011379:Prognosis; D013223:Statistics as Topic