Progressive multifocal leukoencephalopathy: clinical and MR response to treatment.
Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease that occurs in immunocompromised hosts. We describe two patients with biopsy-proved PML who showed improvement clinically and radiologically after medical therapy. These cases reveal that interval improvement can in rare instances be consistent with a diagnosis of PML.
Garrels
K
K
Department of Radiology, Toronto Hospital, Ontario, Canada.
Kucharczyk
W
W
Wortzman
G
G
Shandling
M
M
D000328:Adult; D001921:Brain / Q000473:pathology; D003561:Cytarabine / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D016898:Interferon-alpha / Q000627:therapeutic use*; D007968:Leukoencephalopathy, Progressive Multifocal / Q000175:diagnosis* / Q000503:physiopathology / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged
D016898:Interferon-alpha; D003561:Cytarabine