title: A new familial short stature syndrome: Brussels type.
abstract: A new association of congenital familial short stature with facial dysmorphism and osteochondrodysplastic lesions is described in two siblings. Clinical abnormalities include severe prenatal and postnatal growth failure and facial dysmorphism. Radiographs show osteochondrodysplastic lesions with a narrow thorax, short ribs, epiphyseal maturation delay and slightly deformed metaphyses. Microscopic analysis of the skeleton shows pathological features.
authors.affiliation: Medical Genetics Unit, Centre for Human Genetics, Brussels, Belgium.
authors.forename: C
authors.initials: C
authors.lastname: Mievis
authors.forename: D
authors.initials: D
authors.lastname: Claus
authors.forename: P
authors.initials: P
authors.lastname: Clapuyt
authors.forename: C
authors.initials: C
authors.lastname: Nyssen-Behets
authors.forename: S
authors.initials: S
authors.lastname: Gosseye
authors.forename: P
authors.initials: P
authors.lastname: Malvaux
authors.forename: C
authors.initials: C
authors.lastname: Verellen-Dumoulin
mesh_terms: D001827:Body Height; D005145:Face / Q000002:abnormalities*; D006130:Growth Disorders / Q000151:congenital / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010009:Osteochondrodysplasias / Q000473:pathology*; D013577:Syndrome