title: Cardioprotective effects of ovarian hormones.
abstract: This paper reviews the evidence regarding the cardioprotective effects of oestrogen replacement therapy in postmenopausal women. Oestrogens have been shown to improve serum lipid profiles, carbohydrate metabolism, and insulin sensitivity; prevent the formation and development of atherosclerotic plaque; reduce blood pressure and plasma fibrinogen levels; and favourably affect overall cardiac function. Thus, oestrogen replacement therapy may prevent or inhibit the progression of existing coronary disease, and may also have a protective effect against acute cardiovascular and cerebrovascular ischaemic events.
authors.affiliation: Department of Cardiology, Istituto H. San Raffaele, Milano-Roma, Italy.
authors.forename: G M
authors.initials: GM
authors.lastname: Rosano
authors.forename: S L
authors.initials: SL
authors.lastname: Chierchia
authors.forename: F
authors.initials: F
authors.lastname: Leonardo
authors.forename: C M
authors.initials: CM
authors.lastname: Beale
authors.forename: P
authors.initials: P
authors.lastname: Collins
mesh_terms: D000818:Animals; D001794:Blood Pressure; D002241:Carbohydrates / Q000097:blood; D003327:Coronary Disease / Q000097:blood / Q000503:physiopathology / Q000517:prevention & control*; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D017698:Postmenopause / Q000187:drug effects / Q000378:metabolism; D012307:Risk Factors
chemical_list: D002241:Carbohydrates; D008055:Lipids