title: Optic disc topography before and after trabeculectomy in advanced glaucoma.
abstract: OBJECTIVE
  To analyze changes in the optic disc topography after filtration surgery.
  
  
  METHODS
  Laser scanning tomography was performed in 10 eyes of 9 patients (mean age 65.6 +/- 8.1 years; age range 55 to 75 years) after a mean follow-up of 3.7 months, and in 8 eyes of 7 patients (mean age 63.1 +/- 7.6 years; age range 55 to 75 years) after a mean follow-up of 13.1 months.
  
  
  RESULTS
  Preoperatively, the mean intraocular pressure (IOP) was 24.4 +/- 6.9 mm Hg with maximal medication. Postoperatively at 3.7 months it was 11.0 +/- 2.2 mm Hg, and at l2.1 months it was l3.6 +/- 2.8 mm Hg. An initial reduction in IOP of more than 30 percent at 3.7 months was achieved without medication in all but 1 eye. After 12.1 months, an IOP reduction of more than 30 percent was achieved in 6 of 8 eyes (1 with medication), while 2 eyes had IOP reductions of less than 15 percent (< or = 3 mm Hg) despite medication. In the 6 eyes, the optic disc cup volume showed a decrease of more than 30 percent, while the 2 eyes without marked IOP reductions had slight increases in cup volume. Of the 2 eyes without marked decreases in cup size, 1 had normal-tension glaucoma and 1 experienced an increase in IOP of more than 25 mm Hg during the first postoperative week.
  
  
  CONCLUSIONS
  The postoperative IOP should be kept low enough to permit reversal of optic disc changes.
authors.affiliation: Department of Ophthalmology, University of Helsinki, Finland.
authors.forename: C
authors.initials: C
authors.lastname: Raitta
authors.forename: G
authors.initials: G
authors.lastname: Tomita
authors.forename: E
authors.initials: E
authors.lastname: Vesti
authors.forename: M
authors.initials: M
authors.lastname: Harju
authors.forename: H
authors.initials: H
authors.lastname: Nakao
mesh_terms: D000368:Aged; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D007834:Lasers; D008297:Male; D008875:Middle Aged; D009898:Optic Disk / Q000473:pathology*; D012189:Retrospective Studies; D014054:Tomography / Q000379:methods; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome; D014794:Visual Fields