title: SRS-A antagonist pyranoquinolone alkaloids from east African Fagara plants and their synthesis.
abstract: Three pyranoquinolone alkaloids isolated from two East African Fagara plants have been found to exhibit SRS-A antagonist action. Their synthesis has been accomplished, using a modified Coppola's method or a thermal cyclization followed by an electrocyclic ring closure.
authors.affiliation: Department of Chemistry, Faculty of Science and Technology, Kinki University, Osaka.
authors.forename: T
authors.initials: T
authors.lastname: Kamikawa
authors.forename: Y
authors.initials: Y
authors.lastname: Hanaoka
authors.forename: S
authors.initials: S
authors.lastname: Fujie
authors.forename: K
authors.initials: K
authors.lastname: Saito
authors.forename: Y
authors.initials: Y
authors.lastname: Yamagiwa
authors.forename: K
authors.initials: K
authors.lastname: Fukuhara
authors.forename: I
authors.initials: I
authors.lastname: Kubo
mesh_terms: D042462:4-Quinolones; D000351:Africa, Eastern; D000470:Alkaloids / Q000737:chemistry*; D000890:Anti-Infective Agents / Q000737:chemistry*; D002855:Chromatography, Thin Layer; D010936:Plant Extracts / Q000737:chemistry*; D013189:SRS-A / Q000037:antagonists & inhibitors*; D013055:Spectrophotometry, Infrared; D014197:Trees / Q000737:chemistry*
chemical_list: D042462:4-Quinolones; D000470:Alkaloids; D000890:Anti-Infective Agents; D010936:Plant Extracts; D013189:SRS-A