Stool markers for colorectal cancer screening: future considerations.
Stool screening for colorectal neoplasia has the important advantages of noninvasiveness and affordability over other available screening approaches. However, better markers are needed to improve the sensitivity and specificity of stool screening. A functional classification of stool markers is proposed, based on the mode of luminal marker entry, which may be useful in considering alternative markers.
Ahlquist
D A
DA
Division of Gastroenterology, Mayo Clinic, Rochester, Minn., USA.
Gilbert
J A
JA
D000954:Antigens, Surface / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis*; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000517:prevention & control*; D005243:Feces / Q000737:chemistry* / Q000166:cytology*; D006801:Humans; D039841:Leukocyte L1 Antigen Complex; D009077:Mucins / Q000032:analysis; D019006:Neural Cell Adhesion Molecules / Q000032:analysis; D009780:Occult Blood; D012680:Sensitivity and Specificity
D000954:Antigens, Surface; D014408:Biomarkers, Tumor; D039841:Leukocyte L1 Antigen Complex; D009077:Mucins; D019006:Neural Cell Adhesion Molecules