title: Sarcoidosis mimicking toxoplasmosis with severe hypercalcaemia and normal 1,25-dihydroxy vitamin D.
abstract: We report a case of a female patient with sarcoidosis who presented with a generalized lymphadenopathy and a strong IgG serological test of toxoplasmosis. Progressive lymphadenopathy with a rising plasma calcium (up to 15 mg dL-1) with a normal plasma 1,25-dihydroxy vitamin D concentration occurred later. Corticosteroid therapy resulted in prompt clinical and biochemical responses with normalization of plasma calcium and a significant reduction in 1,25-dihydroxy vitamin D concentration. This is an exceptional presentation of sarcoidosis with severe hypercalcaemia and normal vitamin D metabolites.
authors.affiliation: Department of Internal Medicine, Rambam Medical Center, Technion, Israel.
authors.forename: Y
authors.initials: Y
authors.lastname: Levy
authors.forename: T
authors.initials: T
authors.lastname: Hayek
authors.forename: R
authors.initials: R
authors.lastname: Finkelstein
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000150:complications*; D008206:Lymphatic Diseases / Q000209:etiology; D012507:Sarcoidosis / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D014123:Toxoplasmosis / Q000175:diagnosis*; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood
chemical_list: D014807:Vitamin D; C097949:1,25-dihydroxyvitamin D