title: Immunohistochemical localization of GABA in chameleon retina (Chamaleo Chamaleo).
abstract: We used a policlonal antiserum against GABA and demonstrated GABA-immunoreactivity (GABA-IR) in several populations of amacrine cells in the inner nuclear layer (INL), and other cells in the inner plexiform layer (IPL) of the central and peripheral retina of the chameleon. Horizontal cells do not contain GABA-IR and the chameleon retina is therefore an exception among non-mammals. GABA-IR was not seen in cell bodies in the position of photoreceptor, bipolar and interplexiform cells suggesting that GABA is not involved in synaptic transmission in the outer plexiform layer of chameleon retina.
authors.affiliation: Departamento de Ciencias Morfológicas, Facultad de Medicina, Universidad de Sevilla, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Quesada
authors.forename: C
authors.initials: C
authors.lastname: Chmielewski
authors.forename: J M
authors.initials: JM
authors.lastname: Génis-Gálvez
authors.forename: F A
authors.initials: FA
authors.lastname: Prada
mesh_terms: D000818:Animals; D005260:Female; D007150:Immunohistochemistry; D008116:Lizards / Q000033:anatomy & histology / Q000378:metabolism* / Q000502:physiology; D008297:Male; D012160:Retina / Q000166:cytology / Q000378:metabolism* / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology; D014018:Tissue Distribution; D005680:gamma-Aminobutyric Acid / Q000378:metabolism* / Q000502:physiology
chemical_list: D005680:gamma-Aminobutyric Acid