title: One stage revision arthroplasty of the hip for deep gram negative infection.
abstract: We describe the use of one stage revision arthroplasty of the hip for deep gram negative infections. We have followed up 15 patients for an average of 8 years following operation. Two procedures failed, one at two years due to aseptic loosening and another because of persistent infection. We attribute the low reinfection rate (1/15) to meticulous surgical technique, preoperative parenteral antibiotics and antibiotic loaded cement. Both failures occurred in the two operations performed without antibiotic loaded cement. We do not recommend the use of plain cement for exchange hip arthroplasty in the presence of gram negative infection.
authors.affiliation: John Charnley Research Institute, Wrightington Hospital, Wigan, United Kingdo
authors.forename: V V
authors.initials: VV
authors.lastname: Raut
authors.forename: M S
authors.initials: MS
authors.lastname: Orth
authors.forename: M C
authors.initials: MC
authors.lastname: Orth
authors.forename: P D
authors.initials: PD
authors.lastname: Siney
authors.forename: B M
authors.initials: BM
authors.lastname: Wroblewski
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D006622:Hip Prosthesis / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011475:Prosthesis Failure; D016459:Prosthesis-Related Infections / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D012086:Reoperation; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents