Procorticotrophin releasing hormone is endoproteolytically processed by the prohormone convertase PC2 but not by PC1 within stably transfected CHO-K1 cells.
Perone
M J
MJ
Dept. of Medicine, University of Manchester.
Ahmed
I
I
Linton
E A
EA
Castro
M G
MG
D000818:Animals; D016282:Aspartic Acid Endopeptidases / Q000235:genetics / Q000378:metabolism*; D016466:CHO Cells; D003346:Corticotropin-Releasing Hormone / Q000378:metabolism*; D006224:Cricetinae; D007150:Immunohistochemistry; D045706:Proprotein Convertase 2; D043484:Proprotein Convertases; D011498:Protein Precursors / Q000378:metabolism*; D011499:Protein Processing, Post-Translational; D013381:Subtilisins / Q000235:genetics / Q000378:metabolism*; D014162:Transfection
D011498:Protein Precursors; C041645:pro-corticotropin releasing hormone; D003346:Corticotropin-Releasing Hormone; D043484:Proprotein Convertases; D013381:Subtilisins; D045706:Proprotein Convertase 2; D016282:Aspartic Acid Endopeptidases