Solid phase extraction of 2,4-D from human urine.
A method for determining urinary concentrations of 2,4-D in samples collected from non-occupationally, environmentally exposed individuals was developed. The 2,4-D was extracted from fortified human urine samples using octadecylsilane solid phase extraction cartridges. The average percent recovery for urine samples spiked at 2 and 20 ng/mL was 100% and 93%, respectively. The method detection limit was estimated to be 0.75 ng of 2,4-D per mL of urine based on a 10 mL sample size. The potential use of 2,4-dichlorophenylacetic acid as a surrogate standard was also investigated.
Thompson
T S
TS
Saskatchewan Health Laboratory & Disease Control Services Branch, Regina, Canada.
Treble
R G
RG
D015084:2,4-Dichlorophenoxyacetic Acid / Q000302:isolation & purification / Q000652:urine*; D000096:Acetone / Q000737:chemistry; D004781:Environmental Exposure; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D012015:Reference Standards; D018401:Sample Size; D012821:Silanes / Q000737:chemistry
D012821:Silanes; D000096:Acetone; C024779:octadecylsilane; D015084:2,4-Dichlorophenoxyacetic Acid