Delivery and monitoring of inhaled nitric oxide.
Inhaled nitric oxide is rapidly gaining popularity as a selective pulmonary vasodilator in patients with acute lung injury and pulmonary hypertension. The development of nitric oxide as a drug has bypassed the usual regulatory and commercial processes, and as a result clinicians have devised a wide range of delivery and monitoring systems. This review describes these systems, and discusses their advantages, disadvantages and safety. The monitoring of nitric oxide metabolites is also discussed.
Young
J D
JD
Nuffield Department of Anaesthetics, The Radcliffe Infirmary, Oxford, UK.
Dyar
O J
OJ
D000280:Administration, Inhalation; D000328:Adult; D006801:Humans; D007231:Infant, Newborn; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods*; D009569:Nitric Oxide / Q000008:administration & dosage* / Q000494:pharmacology; D012121:Respiration, Artificial / Q000295:instrumentation / Q000379:methods*; D012449:Safety
D009569:Nitric Oxide