Antisperm antibody and Klinefelter syndrome: does autoimmunity play a role in the pathogenesis?
Serum samples from 18 patients with Klinefelter syndrome (age range 20-22 years) and from a control group of 18 age-matched healthy subjects were analyzed for antisperm antibodies by a noncompetitive enzyme-linked immunosorbent assay. The antisperm antibody values were found higher in 5 patients (27.7%) than the level of 150 mU/100 microliters which was considered the upper level of the normal range (p < 0.01).
Sengül
A
A
Department of Immunology, GATA Medical Faculty, Ankara, Turkey.
Gül
D
D
Sayli
B S
BS
Hacibektaşoğlu
A
A
D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D015551:Autoimmunity / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007713:Klinefelter Syndrome / Q000276:immunology*; D008297:Male; D013094:Spermatozoa / Q000276:immunology*
D001323:Autoantibodies