title: Crystal and molecular structure of a histo-blood group antigen involved in cell adhesion: the Lewis x trisaccharide.
abstract: This work describes the first crystal structure ever reported of a histo-blood group carbohydrate antigen: Le(x). This study provides a detailed description of the conformation of two crystallographic independent molecules in a highly hydrated environment along with their hydrogen bonding properties and packing features. Some interactions observed between adjacent trisaccharides can provide the basis for involvement of Le(x)-Le(x) interactions in cell-cell adhesion.
authors.affiliation: Ingeniérie Moléculaire, Institut National de la Recherche Agronomique, Nantes, France.
authors.forename: S
authors.initials: S
authors.lastname: Pérez
authors.forename: N
authors.initials: N
authors.lastname: Mouhous-Riou
authors.forename: N E
authors.initials: NE
authors.lastname: Nifant'ev
authors.forename: Y E
authors.initials: YE
authors.lastname: Tsvetkov
authors.forename: B
authors.initials: B
authors.lastname: Bachet
authors.forename: A
authors.initials: A
authors.lastname: Imberty
mesh_terms: D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D007983:Lewis Blood Group Antigens / Q000737:chemistry*; D016256:Lewis X Antigen / Q000737:chemistry*; D008958:Models, Molecular; D008969:Molecular Sequence Data
chemical_list: D007983:Lewis Blood Group Antigens; D016256:Lewis X Antigen