Use of immunocytochemistry in the diagnosis of metastatic carcinoma.
Metastasis of unknown primary site is a common clinical problem. Immunohistochemistry has been shown to be a useful tool in the identification of the primary site. The availability of new antibodies specific for a wide range of antigens and working on routinely fixed, paraffin-imbedded material will ensure that this technique will continue to offer useful information in the search for an elusive primary tumour.
Matthews
P
P
Department of Histopathology, City Hospital NHS Trust, Nottingham, UK.
Ellis
I O
IO
D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D009362:Neoplasm Metastasis; D009382:Neoplasms, Unknown Primary / Q000175:diagnosis*; D012680:Sensitivity and Specificity