Application of whole-mount section of lung specimen in study of radiologic-pathologic correlations.
We evaluated the usefulness of the whole-mount section of the inflated-fixed lung specimen in the study of radiologic-pathologic correlations. Altogether, 24 resected fresh lobe specimens with 1.5- to 3.0-cm solitary pulmonary carcinomas or tuberculomas were inflated with air, intrabronchially fixed by infusing Heitzman's solution, and finally cut into 10- to 15-micron-thick whole-mount sections for the histopathological examination. All 24 inflated-fixed lobes were satisfactorily soft as sponge, sufficiently springy, and kept their original shape. All whole-mount sections clearly presented the complete morphological features of the whole lobes, and could be directly observed by the naked eye and examined under microscopy. The use of the whole-mount section of the lung specimen may facilitate precisely and effectively the studies of the radiologic-pathologic correlations.
Yang
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Department of Clinical Radiology, Kuopio University Hospital, Finland.
Soimakallio
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S
D000230:Adenocarcinoma / Q000473:pathology; D002277:Carcinoma / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D016591:Histocytological Preparation Techniques; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D009362:Neoplasm Metastasis / Q000473:pathology; D011859:Radiography; D014375:Tuberculoma / Q000000981:diagnostic imaging / Q000473:pathology