Increased hepatocytic mitotic activity as a diagnostic marker of acute arsenic intoxication. A report of two cases.
We report two patients in whom acute arsenic poisoning was associated with a very peculiar increase in hepatocytic mitotic activity. The recognition of such an unusual picture which is likely to be related to the mitogenic properties of arsenic may be of help in the identification of acute arsenic intoxication, a life-threatening condition which is difficult to diagnose.
Brenard
R
R
Service d'Hépato-gastroentérologie, Cliniques Universitaires St Luc, UCL, Brussels, Belgium
Laterre
P F
PF
Reynaert
M
M
Hantson
P
P
Mahieu
P
P
Buchet
J P
JP
Geubel
A
A
Rahier
J
J
D000208:Acute Disease; D000328:Adult; D020261:Arsenic Poisoning; D015415:Biomarkers; D006801:Humans; D008099:Liver / Q000473:pathology*; D008297:Male; D008938:Mitosis
D015415:Biomarkers