[Primary granulocytic sarcoma of the pancreas: efficacy of early treatment with intensive chemotherapy].
In the absence of systemic chemotherapy after the diagnosis of primary granulocytic sarcoma (PGS), all patients will subsequently develop acute myelogenous leukemia (AML). The authors describe a case of PGS of the head of the pancreas found at laparotomy in a 32-year-old man. The patient received early after surgery, two courses of high-dose chemotherapy and, with a follow-up of 2 years, never developed AML. This rare observation illustrates the necessity of further early systemic chemotherapy after surgical excision of PGS.
Moreau
P
P
Service d'hématologie clinique, CHU Hôtel-Dieu, Nantes, France.
Milpied
N
N
Thomas
O
O
Fiche
M
M
Parys
V
V
Paineau
J
J
Dutin
J P
JP
Harousseau
J L
JL
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D006801:Humans; D007951:Leukemia, Myeloid / Q000188:drug therapy*; D008297:Male; D010190:Pancreatic Neoplasms / Q000188:drug therapy*; D013997:Time Factors