title: Prodromal symptoms in obsessive-compulsive disorder.
abstract: Prodromal symptoms were investigated in 30 patients with obsessive-compulsive disorder. The large majority of patients (93%) reported at least one prodromal symptom before disease onset. Generalized anxiety, irritability, indecision, phobic and somatic anxiety occurred in about half of patients. Also common were depressive symptoms such as fatigue, lowered self-esteem, depressed mood, pessimism, impaired work, and guilt. The results suggest a close association of obsessions and compulsions with affective symptoms.
authors.affiliation: Affective Disorders Program, Department of Psychology, University of Bologna, Italy.
authors.forename: G A
authors.initials: GA
authors.lastname: Fava
authors.forename: G
authors.initials: G
authors.lastname: Savron
authors.forename: C
authors.initials: C
authors.lastname: Rafanelli
authors.forename: S
authors.initials: S
authors.lastname: Grandi
authors.forename: R
authors.initials: R
authors.lastname: Canestrari
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis / Q000523:psychology*; D011569:Psychiatric Status Rating Scales