Disseminated Geotrichum capitatum infection with predominant liver involvement in a patient with non Hodgkin's lymphoma.
Geotrichum capitatum is an emerging opportunistic pathogen which causes invasive disease in immunocompromized patients. We describe a patient with non Hodgkin's lymphoma and disseminated infection by G. capitatum with predominant liver involvement, which was proven by repeated positive blood cultures and a liver biopsy. Staining liver biopsy demonstrated the presence of hyphal elements consistent with G. capitatum. Combined antimycotic treatment with amphotericin B and 5-flucytosine did not eradicate the mycotic infection as shown by the persistence of liver lesions.
Amft
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3rd Division of Internal Medicine, University of Milan, IRCCS Ospedale Maggiore Policlinico, Italy.
Miadonna
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A
Viviani
M A
MA
Tedeschi
A
A
D005260:Female; D005847:Geotrichosis; D005848:Geotrichum; D006801:Humans; D008099:Liver / Q000382:microbiology; D008228:Lymphoma, Non-Hodgkin / Q000150:complications*; D008875:Middle Aged; D009894:Opportunistic Infections