Maternal and neonatal hyponatraemia: a comparison of Hartmanns solution with 5% dextrose for the delivery of oxytocin in labour.
We performed a randomised controlled trial to compare the effect on neonatal and maternal serum sodium of using oxytocin in Hartmanns solution compared to the standard 5% Dextrose regimen for induction or augmentation in labour. We found significantly decreased maternal and neonatal serum sodium concentrations in the 5% Dextrose group compared to the Hartmanns group.
Higgins
J
J
Rotunda Hospital, Dublin, Ireland.
Gleeson
R
R
Holohan
M
M
Cooney
C
C
Darling
M
M
D000328:Adult; D005260:Female; D005312:Fetal Blood / Q000378:metabolism; D005947:Glucose; D006801:Humans; D007010:Hyponatremia / Q000139:chemically induced / Q000517:prevention & control*; D007231:Infant, Newborn; D007552:Isotonic Solutions; D007751:Labor, Induced; D010121:Oxytocin / Q000008:administration & dosage* / Q000009:adverse effects*; D011247:Pregnancy; D011446:Prospective Studies; D000077325:Ringer's Lactate; D012964:Sodium / Q000097:blood
D007552:Isotonic Solutions; D000077325:Ringer's Lactate; D010121:Oxytocin; D012964:Sodium; D005947:Glucose