Carcinoma arising in ectopic hamartomatous thymoma. An ultrastructural study.
We present the ultrastructural features of a case of adenocarcinoma arising in ectopic hamartomatous thymoma in a 31 year old man, in the supraclavicular location. The tumor had a cribriform adenomatous component with a granular cell quality and mimicked a metastatic carcinoma. Ultrastructurally, the spindle cell component revealed clusters of tonofilaments and the tumor cells were attached by well developed desmosomes. The cytoplasm of adenocarcinoma cells contained peculiar cup-shaped bodies derived from the endoplasmic reticulum wrapped around the mitochondria.
Michal
M
M
Sikls Department of Pathology, Medical Faculty, Charles University, Pilsen, Czech Republic.
Neubauer
L
L
Fakan
F
F
D000230:Adenocarcinoma / Q000473:pathology / Q000648:ultrastructure*; D000328:Adult; D006222:Hamartoma / Q000473:pathology; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology / Q000648:ultrastructure*; D013896:Thoracic Diseases / Q000473:pathology; D013899:Thoracic Neoplasms / Q000473:pathology / Q000648:ultrastructure*; D013945:Thymoma / Q000473:pathology / Q000648:ultrastructure*