title: Natural ingredients based cosmetics. Content of selected fragrance sensitizers.
abstract: In the present study, we have investigated 42 cosmetic products based on natural ingredients for content of 11 fragrance substances: geraniol, hydroxycitronellal, eugenol, isoeugenol, cinnamic aldehyde, cinnamic alcohol, alpha-amylcinnamic aldehyde, citral, coumarin, dihydrocoumarin and alpha-hexylcinnamic aldehyde. The study revealed that the 91% (20/22) of the natural ingredients based perfumes contained 0.027%-7.706% of 1 to 7 of the target fragrances. Between 1 and 5 of the chemically defined synthetic constituents of fragrance mix were found in 82% (18/22) of the perfumes. 35% (7/20) of the other cosmetic products (shampoos, creams, tonics, etc) were found to contain 0.0003-0.0820% of 1 to 3 of the target fragrances. Relatively high concentrations of hydroxycitronellal, coumarin, cinnamic alcohol and alpha-amyl cinnamic aldehyde were found in some of the investigated products. The detection of hydroxycitronellal and alpha-hexylcinnamic aldehyde in some of the products demonstrates that artificial fragrances, i.e., compounds not yet regarded as natural substances, may be present in products claimed to be based on natural ingredients.
authors.affiliation: Ministry of Environment and Energy, National Environmental Research Institute, Roskilde, Denmark.
authors.forename: S C
authors.initials: SC
authors.lastname: Rastogi
authors.forename: J D
authors.initials: JD
authors.lastname: Johansen
authors.forename: T
authors.initials: T
authors.lastname: Menné
mesh_terms: D000433:1-Propanol / Q000009:adverse effects / Q000032:analysis; D000171:Acrolein / Q000009:adverse effects / Q000031:analogs & derivatives / Q000032:analysis; D000080462:Acyclic Monoterpenes; D000447:Aldehydes / Q000009:adverse effects / Q000032:analysis; D000485:Allergens / Q000009:adverse effects / Q000032:analysis*; D003358:Cosmetics / Q000009:adverse effects / Q000032:analysis*; D003374:Coumarins / Q000009:adverse effects / Q000032:analysis; D004643:Emollients / Q000009:adverse effects / Q000032:analysis; D005054:Eugenol / Q000009:adverse effects / Q000031:analogs & derivatives / Q000032:analysis; D006203:Hair Preparations / Q000009:adverse effects / Q000032:analysis; D006801:Humans; D039821:Monoterpenes; D010476:Perfume / Q000009:adverse effects / Q000032:analysis*; D020005:Propanols; D013729:Terpenes / Q000009:adverse effects / Q000032:analysis
chemical_list: D000080462:Acyclic Monoterpenes; D000447:Aldehydes; D000485:Allergens; D003358:Cosmetics; D003374:Coumarins; D004643:Emollients; D006203:Hair Preparations; D039821:Monoterpenes; D010476:Perfume; D020005:Propanols; D013729:Terpenes; C080043:hexyl cinnamic aldehyde; C037028:2-pentylcinnamaldehyde; D005054:Eugenol; C036643:isoeugenol; D000171:Acrolein; C020755:hydroxycitronellal; D000433:1-Propanol; C030123:coumarin; C007836:geraniol; C026308:3,4-dihydrocoumarin; C012843:cinnamaldehyde; C020722:cinnamyl alcohol; C007076:citral