Direct activity of recombinant human lactoferrin against Helicobacter pylori.
We report the activity of recombinant human lactoferrin against Helicobacter pylori. Lactoferrin exerted a time- and dose-dependent action against 8 of the 13 clinical isolates of H. pylori tested in vitro. These results highlight a potential therapeutic use for lactoferrin against H.pylori infection.
Miehlke
S
S
Department of Medicine, Veterans Affairs Medical Center, Houston, Texas, USA.
Reddy
R
R
Osato
M S
MS
Ward
P P
PP
Conneely
O M
OM
Graham
D Y
DY
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016480:Helicobacter pylori / Q000187:drug effects*; D006801:Humans; D007781:Lactoferrin / Q000235:genetics / Q000494:pharmacology*; D011994:Recombinant Proteins / Q000235:genetics / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D011994:Recombinant Proteins; D007781:Lactoferrin