title: Sclerotherapy in bleeding gastric varices of hepatic schistosomiasis.
abstract: We report the results of sclerotherapy in 20 patients with bleeding gastric varices due to hepatic schistosomiasis. In an endemic area, patients with hepatic schistosomiasis, and bleeding gastric varices seen on endoscopy to be inferior extension of esophageal varices, were treated with emergency endoscopic injection just proximal to the cardia. Hemostasis was achieved in 17. Obliteration of varices was achieved in all patients with sclerotherapy, combined with surgery. Thirteen patients who had not been operated on in the past and consented to surgery underwent esophagogastric devascularization with splenectomy. Surgery was carried out as an emergency in the three patients who did not respond to sclerotherapy and electively in 10 patients after control of bleeding. After surgery, sclerotherapy was required for remnant varices. One patient with Child-Pugh grade C cirrhosis died of hepatic encephalopathy after control of the bleed. During a median follow-up of 9 months (range, 1-25 months), recurrence of bleeding in one patient and recurrent varices in two others were controlled with sclerotherapy. One patient had a fatal hemorrhage at home. We conclude that sclerotherapy effectively controls acutely bleeding type 1 gastric varices. Combined with esophagogastric devascularization and splenectomy, long-term results may be encouraging in patients with hepatic schistosomiasis.
authors.affiliation: Departments of Internal Medicine and Surgery, King Khalid Hospital, Najran, Saudi Arabia.
authors.forename: Q Q
authors.initials: QQ
authors.lastname: Contractor
authors.forename: T Q
authors.initials: TQ
authors.lastname: Contractor
authors.forename: Y R
authors.initials: YR
authors.lastname: Kher
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D004932:Esophageal and Gastric Varices / Q000209:etiology / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008109:Liver Diseases, Parasitic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D012552:Schistosomiasis / Q000150:complications*; D012597:Sclerosing Solutions / Q000627:therapeutic use; D015911:Sclerotherapy / Q000379:methods; D012981:Sodium Tetradecyl Sulfate / Q000627:therapeutic use
chemical_list: D012597:Sclerosing Solutions; D012981:Sodium Tetradecyl Sulfate