Malignant melanoma of the vagina in pregnancy: description of a clinical case.
Vaginal melanoma in pregnancy is a rare but extremely malignant tumour for which the prognosis is worsened by the fact that pregnancy increases the secretion of Melanocyte-Stimulating Hormone (MSH). The clinical case is described of a malignant vaginal melanoma in a 27 year-old woman in her 38th week of gestation, who was referred for slight vaginal bleeding. Clinical examination revealed a 3 cm pedunculate tumour on the anterior wall of the vagina. Vaginal cytology suggested a melanoma and instrumental examination failed to reveal any lymph node involvement. The vaginal tumour was removed during a caesarean section and subsequent histological examination identified it as a Breslow Stage II malignant melanoma. A 24-month follow-up showed the patient to have been completely cured.
Zarcone
R
R
2nd Faculty of Gynaecology and Obstetrics, II University of Naples.
Cardone
G
G
Bellini
P
P
Cardone
A
A
D000328:Adult; D002585:Cesarean Section; D005260:Female; D006801:Humans; D008545:Melanoma / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D014625:Vaginal Neoplasms / Q000473:pathology / Q000601:surgery*