title: Accumulation of Tc-99m HMDP in hepatic metastasis from colon carcinoma without detectable calcification.
abstract: A 51-year-old man was found to have hepatic metastasis from colon carcinoma. Bone scintigraphy with 99mTc-hydroxymethylene diphosphonate showed a ringlike accumulation corresponding to the hepatic mass, which was without calcification on computed tomography. Treatment with chemotherapeutic agents was started. After 4 months, computed tomography showed that the mass was smaller than before and that the margin was calcified. The extraosseous accumulation of the radionuclide may be evidence supporting earlier speculation on calcification that could not yet be detected by computed tomography.
authors.affiliation: Third Department of Internal Medicine, Osaka City University Medical School, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Shiomi
authors.forename: T
authors.initials: T
authors.lastname: Kuroki
authors.forename: I
authors.initials: I
authors.lastname: Hasegawa
authors.forename: H
authors.initials: H
authors.lastname: Nishio
authors.forename: K
authors.initials: K
authors.lastname: Azuma
authors.forename: H
authors.initials: H
authors.lastname: Ochi
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001842:Bone and Bones / Q000000981:diagnostic imaging; D002114:Calcinosis; D002945:Cisplatin / Q000008:administration & dosage; D003110:Colonic Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy; D017809:Fatal Outcome; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D013669:Technetium Tc 99m Medronate / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed
chemical_list: C024226:technetium Tc 99m hydroxymethylene diphosphonate; D002945:Cisplatin; D005472:Fluorouracil; D013669:Technetium Tc 99m Medronate