Mechanisms of neuronal cell death. An overview.
Neuronal cell death is both a vital component of the embryo-genesis of the nervous system and forms the basis of all neurodegenerative diseases. This overview explores the fundamental mechanisms underlying neuronal cell death at a cellular and molecular level. The significance of the mode of neuronal death is compared with respect to physiological (developmental) and pathological neuronal loss.
Waters
C M
CM
Division of Neuroscience, University of Manchester, UK.
D000818:Animals; D017209:Apoptosis; D001921:Brain / Q000166:cytology / Q000473:pathology*; D001927:Brain Diseases / Q000473:pathology* / Q000503:physiopathology; D016923:Cell Death / Q000235:genetics; D006801:Humans; D009474:Neurons / Q000166:cytology* / Q000473:pathology / Q000502:physiology*