title: Prenatal diagnosis of amniotic band syndrome in a methadone user: review of the literature and a case report.
abstract: We present a case and review of the literature of an amniotic band causing malformation in the distal forearm in a baby born to a methadone-dependent mother. This diagnosis was made prenatally at the routine 18-20-week gestation anomaly ultrasound scan. Histology of the amniotic band postpartum revealed hair shafts within its structure. This has not previously been documented, nor has an association of this syndrome with systematic abuse of methadone. The fact that this anomaly could be detected by prenatal ultrasound scanning is of value in the counselling of high-risk pregnancies such as this.
authors.affiliation: Department of Radiology, Chelsea and Westminster Hospital, London, UK.
authors.forename: C A
authors.initials: CA
authors.lastname: Daly
authors.forename: J
authors.initials: J
authors.lastname: Freeman
authors.forename: W
authors.initials: W
authors.lastname: Weston
authors.forename: I
authors.initials: I
authors.lastname: Kovar
authors.forename: M
authors.initials: M
authors.lastname: Phelan
mesh_terms: D000328:Adult; D000652:Amniotic Band Syndrome / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D005542:Forearm / Q000002:abnormalities / Q000000981:diagnostic imaging; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008691:Methadone; D011247:Pregnancy; D018566:Pregnancy, High-Risk; D011859:Radiography; D019966:Substance-Related Disorders / Q000150:complications*; D016216:Ultrasonography, Prenatal
chemical_list: D008691:Methadone