title: Extracapillary glomerulonephritis in a patient with juvenile chronic arthritis.
abstract: A patient with juvenile chronic arthritis (JCA) in remission developed the nephrotic syndrome 17 years after the onset of the disease. A renal biopsy showed diffuse extracapillary proliferative glomerulonephritis without immune complex deposits. The patient was treated with glucocortico-steroids and cyclophosphamide. Extracapillary glomerulonephritis without immune complex deposits appears to be a rare complication of JCA.
authors.affiliation: Department of Rheumatology, University Hospital Leiden, The Netherlands.
authors.forename: J C
authors.initials: JC
authors.lastname: Mertens
authors.forename: T W
authors.initials: TW
authors.lastname: Huizinga
authors.forename: E C
authors.initials: EC
authors.lastname: Hagen
authors.forename: A A
authors.initials: AA
authors.lastname: Hollander
authors.forename: A J
authors.initials: AJ
authors.lastname: Peeters
authors.forename: J A
authors.initials: JA
authors.lastname: Bruijn
authors.forename: J D
authors.initials: JD
authors.lastname: MacFarlane
authors.forename: B A
authors.initials: BA
authors.lastname: Dijkmans
mesh_terms: D000328:Adult; D001171:Arthritis, Juvenile / Q000150:complications*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005921:Glomerulonephritis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007668:Kidney / Q000473:pathology; D009404:Nephrotic Syndrome / Q000209:etiology
chemical_list: D005938:Glucocorticoids; D003520:Cyclophosphamide