The target of PKC induced suppression of adenosine inhibition of glutamate release from synaptosomes is downstream of the A1 receptor and G-protein coupling.
Budd
D C
DC
Dept. of Pharmacology, Ninewells Medical School, Dundee, UK.
Nicholls
D G
DG
McLaughlin
M
M
D000241:Adenosine / Q000378:metabolism*; D000818:Animals; D019204:GTP-Binding Proteins / Q000378:metabolism; D018698:Glutamic Acid / Q000378:metabolism*; D016244:Guanosine 5'-O-(3-Thiotriphosphate) / Q000378:metabolism; D066298:In Vitro Techniques; D007527:Isoenzymes / Q000378:metabolism*; D015240:Phorbol 12,13-Dibutyrate / Q000494:pharmacology; D011493:Protein Kinase C / Q000378:metabolism*; D051745:Protein Kinase C-delta; D051381:Rats; D018047:Receptors, Purinergic P1 / Q000378:metabolism; D013574:Synaptosomes / Q000187:drug effects / Q000378:metabolism*
D007527:Isoenzymes; D018047:Receptors, Purinergic P1; D015240:Phorbol 12,13-Dibutyrate; D016244:Guanosine 5'-O-(3-Thiotriphosphate); D018698:Glutamic Acid; C497260:Prkcd protein, rat; D011493:Protein Kinase C; D051745:Protein Kinase C-delta; D019204:GTP-Binding Proteins; D000241:Adenosine