Extracapillary glomerulonephritis in a patient with juvenile chronic arthritis.
A patient with juvenile chronic arthritis (JCA) in remission developed the nephrotic syndrome 17 years after the onset of the disease. A renal biopsy showed diffuse extracapillary proliferative glomerulonephritis without immune complex deposits. The patient was treated with glucocortico-steroids and cyclophosphamide. Extracapillary glomerulonephritis without immune complex deposits appears to be a rare complication of JCA.
Mertens
J C
JC
Department of Rheumatology, University Hospital Leiden, The Netherlands.
Huizinga
T W
TW
Hagen
E C
EC
Hollander
A A
AA
Peeters
A J
AJ
Bruijn
J A
JA
MacFarlane
J D
JD
Dijkmans
B A
BA
D000328:Adult; D001171:Arthritis, Juvenile / Q000150:complications*; D003520:Cyclophosphamide / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005921:Glomerulonephritis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007668:Kidney / Q000473:pathology; D009404:Nephrotic Syndrome / Q000209:etiology
D005938:Glucocorticoids; D003520:Cyclophosphamide