Acinic cell-like carcinoma of the breast.
A case of infiltrating carcinoma of the breast with features similar to those seen in acinic cell carcinoma of the parotid gland is described in a 42-year-old woman. The neoplastic cells were immunoreactive with anti-lysozyme- and anti-salivary-type amylase antisera and contained electron-dense cytoplasmic globules similar to those seen in acinic cell carcinoma of salivary glands. One lymph node out of 18 was found to contain a metastatic deposit. The patient is alive and well 1 year after mastectomy. This appears to be the first case of carcinoma with acinic cell-like features reported in the breast.
Roncaroli
F
F
Instituto Anatomia ed Istologia Patologica, Ospedale Bellaria, Bologna, Italy.
Lamovec
J
J
Zidar
A
A
Eusebi
V
V
D000328:Adult; D000681:Amylases / Q000032:analysis / Q000276:immunology; D001943:Breast Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure; D018267:Carcinoma, Acinar Cell / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D006801:Humans; D007106:Immune Sera / Q000032:analysis / Q000276:immunology; D007150:Immunohistochemistry; D008198:Lymph Nodes / Q000473:pathology; D008854:Microscopy, Electron; D009113:Muramidase / Q000032:analysis / Q000276:immunology; D010307:Parotid Neoplasms / Q000737:chemistry / Q000473:pathology / Q000648:ultrastructure
D007106:Immune Sera; D000681:Amylases; D009113:Muramidase