title: Major acute inflammatory complications of diverticular disease of the colon: planning of surgical management.
abstract: OBJECTIVE
  The aim of this study was to determine the most appropriate surgical strategy in the management of patients with major inflammatory complications of colonic diverticular disease.
  
  
  METHODS
  Out of 259 patients affected by complicated diverticular disease of the colon, 43 consecutive patients (16.6%) who underwent urgent or emergency surgical intervention for diverticular perforation during a 20-year period (1975-1994) were retrospectively analyzed. According to the changes in the surgical approach over the time, the series was divided into two groups: 1975-1985 group A (n = 23), 1986-1994 group B (n = 20). The clinical diagnosis was confirmed by operative and pathologic findings.
  
  
  RESULTS
  Out of 43 patients, 11 underwent derivative procedure and 32 resection. There were no significant differences among the two groups of patients according to sex ratio and mean age. The overall percentage of patients in group B who underwent resective procedure (100%) was significantly greater in comparison with that in group A (52%) (p < 0.001). Colostomy and drainage was employed only during the first period (30%)(vs group B, p < 0.05) and the proportion of patients who underwent primary resection and anastomosis was significantly higher during the second period (45%) (vs group A, p < 0.05).
  
  
  CONCLUSIONS
  It must be stressed that resection of the diseased segment at initial operation appears mandatory; one-stage procedure is indicated when infection is confined to the mesentery, while resection and anastomosis with covering colostomy (two-stage procedure) is preferable whenever peritoneal contamination has occurred. Hartmann's operation remains the procedure of choice in the patients presenting known impaired immunity or fecal contamination.
authors.affiliation: Department of Surgery, University of Rome Tor Vergata, University of Parma.
authors.forename: G
authors.initials: G
authors.lastname: Tucci
authors.forename: A
authors.initials: A
authors.lastname: Torquati
authors.forename: M
authors.initials: M
authors.lastname: Grande
authors.forename: I
authors.initials: I
authors.lastname: Stroppa
authors.forename: M
authors.initials: M
authors.lastname: Sianesi
authors.forename: A M
authors.initials: AM
authors.lastname: Farinon
mesh_terms: D018784:Abdominal Abscess / Q000209:etiology* / Q000401:mortality / Q000601:surgery*; D000714:Anastomosis, Surgical; D016022:Case-Control Studies; D003125:Colostomy; D004239:Diverticulitis, Colonic / Q000150:complications* / Q000401:mortality / Q000601:surgery; D004322:Drainage; D005260:Female; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology* / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012810:Sigmoid Diseases / Q000150:complications* / Q000401:mortality / Q000601:surgery