title: Dombrock blood group (DO): assignment to chromosome 12p.
abstract: The Dombrock blood group system (DO) is a common polymorphism in Caucasians, represented by two red cell antigen alleles. In a linkage study in our family material of 832 families from the Copenhagen area, we found a strong indication of tight linkage with the two flanking DNA polymorphisms D12S358 (z = 7.66; at theta M = 0.001, theta F = 0.031) and D12S364 (z = 8.53; at theta M = 0.068, theta F = 0.031). DO is assigned to the region 12p13.2-12p12.1 by physically localised markers.
authors.affiliation: Institute of Medical Biochemistry and Genetics, Department of Genetics, Copenhagen N, Denmark. he@rclink.imbg.ku.dk
authors.forename: H
authors.initials: H
authors.lastname: Eiberg
authors.forename: J
authors.initials: J
authors.lastname: Mohr
mesh_terms: D001789:Blood Group Antigens / Q000235:genetics*; D002881:Chromosomes, Human, Pair 12; D005260:Female; D008040:Genetic Linkage; D006801:Humans; D008297:Male; D010375:Pedigree; D012150:Polymorphism, Restriction Fragment Length; D044465:White People / Q000235:genetics
chemical_list: D001789:Blood Group Antigens