title: Comparative anticoagulant effects of various thrombin inhibitors, as determined in the ecarin clotting time method.
authors.affiliation: Department of Pathology, Loyola University Chicago, Stritch School of Medicine, Maywood, IL 60153, USA.
authors.forename: D D
authors.initials: DD
authors.lastname: Callas
authors.forename: J
authors.initials: J
authors.lastname: Fareed
mesh_terms: D000991:Antithrombins / Q000494:pharmacology*; D001120:Arginine / Q000031:analogs & derivatives; D001780:Blood Coagulation Tests; D001896:Boron Compounds / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D010450:Endopeptidases / Q000494:pharmacology*; D004792:Enzyme Precursors / Q000378:metabolism; D005343:Fibrinolytic Agents / Q000494:pharmacology*; D006493:Heparin / Q000494:pharmacology; D006629:Hirudins / Q000494:pharmacology; D006801:Humans; D009842:Oligopeptides / Q000494:pharmacology*; D010314:Partial Thromboplastin Time; D010875:Pipecolic Acids / Q000494:pharmacology; D011516:Prothrombin / Q000187:drug effects / Q000378:metabolism; D013449:Sulfonamides; D013917:Thrombin / Q000378:metabolism
chemical_list: D000991:Antithrombins; D001896:Boron Compounds; D004792:Enzyme Precursors; D005343:Fibrinolytic Agents; D006629:Hirudins; D009842:Oligopeptides; D010875:Pipecolic Acids; D013449:Sulfonamides; C066061:acetylphenylalanyl-prolyl-boroarginine; C104714:N-methylphenylalanyl-prolyl-arginine; C044749:butyloxycarbonyl-phenylalanyl-prolyl-arginine; C077952:phenylalanyl-prolyl-arginine; D011516:Prothrombin; D006493:Heparin; D001120:Arginine; D010450:Endopeptidases; D013917:Thrombin; C026812:meizothrombin; C020097:ecarin; C031942:argatroban