title: Decrease in selenium status in relation to coal dust exposure.
abstract: Selenium (Se) plasma levels were studied in 222 coal miners to assess whether selenium is decreased in relation to coal dust exposure, taking age, alcohol, and tobacco consumption into account. Selenium levels decreased significantly with age and current tobacco consumption, among miners aged 34-50. Long-term and current exposure to coal dust were studied. The lowest Se values were observed for those with both long-term and current exposure (60.2 ng/ml), the highest for those never or slightly exposed (64.1 ng/ml); those with long-term exposure not currently exposed fell in an intermediate position (61.3 ng/ml). No relation was observed with alcohol consumption. The association of coal dust with low selenium remained significant after adjustment for age and smoking.
authors.affiliation: INSERM Unit 169, Villejuif, France.
authors.forename: M P
authors.initials: MP
authors.lastname: Oryszczyn
authors.forename: J
authors.initials: J
authors.lastname: Godin
authors.forename: C
authors.initials: C
authors.lastname: Frette
authors.forename: G
authors.initials: G
authors.lastname: Hellier
authors.forename: J P
authors.initials: JP
authors.lastname: Bertrand
authors.forename: Q T
authors.initials: QT
authors.lastname: Pham
authors.forename: F
authors.initials: F
authors.lastname: Kauffmann
mesh_terms: D000328:Adult; D000367:Age Factors; D000428:Alcohol Drinking / Q000009:adverse effects / Q000097:blood; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D003031:Coal / Q000009:adverse effects*; D003032:Coal Mining; D004391:Dust / Q000009:adverse effects*; D005602:France; D006801:Humans; D016014:Linear Models; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D012643:Selenium / Q000097:blood*; D012907:Smoking / Q000009:adverse effects / Q000097:blood; D013997:Time Factors
chemical_list: D003031:Coal; D004391:Dust; D012643:Selenium