title: Up and down the growth hormone cascade.
abstract: In this review we present a personal overview of current research at different levels of the control cascade that regulates growth hormone and insulin-like growth factors, the primary endocrine regulators of post-natal growth and metabolism. Given the broad scope of this topic we have focused on only a few key areas of current interest.
authors.affiliation: Discovery Research, Genentech Inc, South San Francisco, CA 94080, USA. ross@gene.com
authors.forename: R G
authors.initials: RG
authors.lastname: Clark
authors.forename: I C
authors.initials: IC
authors.lastname: Robinson
mesh_terms: D000818:Animals; D002352:Carrier Proteins / Q000097:blood; D005246:Feedback; D005818:Genetic Engineering; D013006:Growth Hormone / Q000502:physiology*; D013007:Growth Hormone-Releasing Hormone / Q000502:physiology*; D019382:Human Growth Hormone / Q000502:physiology*; D006801:Humans; D011986:Receptors, Somatotropin / Q000819:agonists / Q000037:antagonists & inhibitors; D013002:Somatomedins / Q000502:physiology*
chemical_list: D002352:Carrier Proteins; D011986:Receptors, Somatotropin; D013002:Somatomedins; D019382:Human Growth Hormone; D013006:Growth Hormone; D013007:Growth Hormone-Releasing Hormone