Peroperative (123)I-MIBG scan using a sterile probe for staging and resection of neuroblastoma in children.
Two children with neuroblastoma were treated at Bristol Children's Hospital. One had primary resection of a right adrenal tumor; the other had resection of a secondary lymph node located in the left supraclavicular fossa. In both cases, the patients received 123(I)-meta-iodobenzylguanidine (MIBG) preoperatively, and a sterilizable, hand-held Cadmium-Telluride (CdTe) solid-state detector was used for localization of the tumor. The surgical procedure was facilitated significantly by this peroperative radioisotope-guided technique.
Aslam
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A
Department of Paediatric Surgery, Bristol Royal Hospital for Sick Children, Bristol, England.
Perkins
A C
AC
Spicer
R D
RD
D019797:3-Iodobenzylguanidine; D000310:Adrenal Gland Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D000315:Adrenalectomy; D003287:Contrast Media; D005260:Female; D006801:Humans; D007223:Infant; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D009367:Neoplasm Staging; D009447:Neuroblastoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D011877:Radionuclide Imaging; D012588:Scintillation Counting / Q000295:instrumentation*; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D013242:Sterilization
D003287:Contrast Media; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D019797:3-Iodobenzylguanidine