Hepatic amyloidosis presenting with severe intrahepatic cholestasis.
Systemic amyloidosis presenting with jaundice is rare. A case of primary amyloidosis presenting with severe intrahepatic cholestasis is reported. The patient had hepatomegaly, ascites, and a markedly elevated serum alkaline phosphatase level. He had a rapid downhill course resulting in death. Autopsy showed evidence of amyloidosis involving multiple organs, including the liver, kidney, and heart.
Goenka
M K
MK
Department of Gastroenterology, Postgraduate Institute of Medical 4ducation and Research, Chandigarh, India.
Bhasin
D K
DK
Vasisth
R K
RK
Dhawan
S
S
D000328:Adult; D000686:Amyloidosis / Q000175:diagnosis* / Q000473:pathology; D001707:Biopsy, Needle; D002780:Cholestasis, Intrahepatic / Q000175:diagnosis* / Q000473:pathology; D006529:Hepatomegaly / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D008107:Liver Diseases / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D014057:Tomography, X-Ray Computed