title: The association between tumour necrosis factor-alpha, interleukin-6 and microbiological findings in the synovial fluid of aborted and neonatal calves.
abstract: Tumour necrosis factor-alpha (TNF alpha) and interleukin-6 (IL-6) were detected in the intra-carpal synovial fluids collected from aborted and recently dead young calves. Five out of seven TNF-alpha positive joint fluids were bacteriologically positive and two were sterile. Only one out of 20 TNF-alpha negative joint aspirates was infected (P = 0.0014). Sixteen of the synovial fluid samples were examined for the presence of IL-6. In 12 samples IL-6 was detected, six of which were bacteriologically contaminated. Four out of the 16 samples were IL-6 negative. These findings indicated the possible association between TNF-alpha and the intra-articular inflammatory processes in young calves, which in the present study were either found in combination with or without IL-6.
authors.affiliation: Department of Immunology, Kimron Veterinary Institute, Bet Dagan, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Meirom
authors.forename: S
authors.initials: S
authors.lastname: Moss
authors.forename: M
authors.initials: M
authors.lastname: Bernstein
authors.forename: Z
authors.initials: Z
authors.lastname: Bider
authors.forename: J
authors.initials: J
authors.lastname: Brenner
mesh_terms: D000034:Abortion, Veterinary / Q000276:immunology / Q000382:microbiology; D000818:Animals; D000831:Animals, Newborn; D001170:Arthritis, Infectious / Q000276:immunology / Q000662:veterinary*; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology*; D005260:Female; D015850:Interleukin-6 / Q000032:analysis*; D011247:Pregnancy; D013582:Synovial Fluid / Q000737:chemistry* / Q000382:microbiology; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis*
chemical_list: D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha