Mitochondrial DNA mutations in diabetic heart.
Mutations of mitochondrial DNA have been found in cardiomyopathic and diabetic patients as well as mitochondrial myopathic patients. Mitochondrial DNA mutations are maternally transmitted. It has also been reported that these mutations can be acquired under the influence of free radicals. This article is a mini-review about mutations of mitochondrial DNA related to the diabetic heart.
Takeda
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Department of Internal Medicine, Aoto Hospital, Jikei University, School of Medicine, Tokyo, Japan.
D009202:Cardiomyopathies / Q000150:complications / Q000235:genetics*; D004272:DNA, Mitochondrial / Q000235:genetics*; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000235:genetics*; D006801:Humans; D009154:Mutation; D017354:Point Mutation
D004272:DNA, Mitochondrial