title: Hemangioblastomas of the spinal cord and the brainstem: diagnostic and therapeutic features.
abstract: Hemangioblastomas of the spinal cord and the brainstem make up 4% of all spinal tumors and are less common than cerebellar hemangioblastomas. CT and MRI are essential for preoperative diagnosis. Nevertheless, cerebral and spinal angiography are also mandatory, since they allow a detailed study of the vascular situation, which is decisive for exact planning of a surgical strategy. The purpose of this study was to evaluate the diagnostic and therapeutic factors which influence surgical morbidity and postoperative outcome. Twelve patients harbouring spinal(8 cases) or medullary (4 cases) hemangioblastomas, all symptomatic with sensorimotor deficits corresponding to the level of the lesion were evaluated. All patients were treated in our department between December 1989 and September 1994. Complete resection of the lesion was achieved in each case. Postoperatively, none of the patients showed deterioration. Nine patients had immediate postoperative improvement of neurological signs and symptoms; in three patients the initial neurological deficits remained unchanged during the in-patient period. Late postoperative outcome demonstrated a clear improvement; in only one patient was there no change of the clinical signs, while in the other 11 patients a significant improvement of pre-existing neurological deficits was experienced. We conclude that microsurgical resection of spinal and medullary hemangioblastomas with low morbidity is feasible.
authors.affiliation: Department of Neurosurgery, Technical University(RWTH) Aachen, Fed. Rep. of Germany.
authors.forename: U
authors.initials: U
authors.lastname: Spetzger
authors.forename: H
authors.initials: H
authors.lastname: Bertalanffy
authors.forename: B
authors.initials: B
authors.lastname: Huffmann
authors.forename: L
authors.initials: L
authors.lastname: Mayfrank
authors.forename: J
authors.initials: J
authors.lastname: Reul
authors.forename: J M
authors.initials: JM
authors.lastname: Gilsbach
mesh_terms: D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D003952:Diagnostic Imaging; D005260:Female; D018325:Hemangioblastoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007796:Laminectomy; D008297:Male; D008526:Medulla Oblongata / Q000473:pathology / Q000601:surgery*; D008866:Microsurgery; D008875:Middle Aged; D009460:Neurologic Examination; D011183:Postoperative Complications / Q000175:diagnosis; D012086:Reoperation; D013120:Spinal Cord Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome; D006623:von Hippel-Lindau Disease / Q000175:diagnosis / Q000473:pathology / Q000601:surgery