Treatment of Oslerus osleri infestation in a dog: case report and literature review.
Oslerus osleri (O. osleri), found throughout the world, reportedly is the most common respiratory nematode of wild and domestic dogs. Oslerus osleri infestation was diagnosed in a 1.5-year-old Scottish terrier presenting with a seven-week history of progressive cough. Diagnosis was based upon visualization of characteristic lesions on bronchoscopic evaluation and recovery of O. osleri larvae from tracheal and bronchoalveolar lavage samples on fecal analyses. Therapy was successful using anti-inflammatory doses of prednisone (0.5 mg/kg body weight, per os [PO] every other day) and thiabendazole (35 mg/kg body weight, PO q 12 hrs for five days; then 70 mg/kg body weight, PO q 12 hrs for 21 days).
Levitan
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Department of Small Animal Medicine, Foster Hospital for Small Animals at Tufts University School of Veterinary Medicine, North Grafton, Massachusetts 01536, USA.
Matz
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Findlen
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Fister
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D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000969:Antinematodal Agents / Q000627:therapeutic use*; D001835:Body Weight / Q000187:drug effects / Q000502:physiology; D001992:Bronchoalveolar Lavage Fluid / Q000469:parasitology; D001999:Bronchoscopy / Q000662:veterinary; D004283:Dog Diseases / Q000188:drug therapy* / Q000469:parasitology / Q000473:pathology; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D009348:Nematoda / Q000302:isolation & purification*; D009349:Nematode Infections / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D011241:Prednisone / Q000627:therapeutic use; D013827:Thiabendazole / Q000627:therapeutic use; D014132:Trachea / Q000469:parasitology / Q000473:pathology
D000893:Anti-Inflammatory Agents; D000969:Antinematodal Agents; D013827:Thiabendazole; D011241:Prednisone