title: Reduction of coronary heart disease risk factors in the German cardiovascular prevention study.
abstract: BACKGROUND
  In six regions of former West Germany, a community-oriented prevention program for coronary heart disease (CHD) was conducted over a 7-year period.
  
  
  METHODS
  In the intervention regions, CHD prevention activities were performed with special emphasis on healthy nutrition, increased physical activity, and reduction of smoking, hypertension, and hypercholesterolemia. The impact of these activities on CHD risk factor trends was observed in three independent samples of the intervention regions. Three independent representative samples of the total West German population were used as a reference. Linear regression models with interaction terms to represent the intervention effects were used to test for differences in risk factor trends.
  
  
  RESULTS
  In the pooled intervention regions, a net reduction in mean values of systolic (-2.0%) and diastolic (-2.0%) blood pressure, total serum cholesterol (-1.8%), as well as the percentage of smokers (-6.7%) was observed compared with the nationwide trend. From the major CHD risk factors, only body mass index was not influenced in the intervention population.
  
  
  CONCLUSIONS
  The community-oriented German Cardiovascular Prevention program can effectively be used to reduce CHD risk factors in a broad population.
authors.affiliation: Robert Koch Institute, Berlin, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Hoffmeister
authors.forename: G B
authors.initials: GB
authors.lastname: Mensink
authors.forename: H
authors.initials: H
authors.lastname: Stolzenberg
authors.forename: J
authors.initials: J
authors.lastname: Hoeltz
authors.forename: H
authors.initials: H
authors.lastname: Kreuter
authors.forename: U
authors.initials: U
authors.lastname: Laaser
authors.forename: E
authors.initials: E
authors.lastname: Nüssel
authors.forename: K D
authors.initials: KD
authors.lastname: Hüllemann
authors.forename: J V
authors.initials: JV
authors.lastname: Troschke
mesh_terms: D000328:Adult; D000368:Aged; D003153:Community Health Services / Q000458:organization & administration*; D003327:Coronary Disease / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D005858:Germany / Q000453:epidemiology; D006801:Humans; D008019:Life Style; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011314:Preventive Health Services / Q000458:organization & administration*; D015397:Program Evaluation; D012307:Risk Factors