title: Successful management of hemolysis in ABO-nonidentical orthotopic liver transplantation by steroid therapy: a case report.
abstract: Hemolysis due to donor-derived B lymphocytes has been reported in patients who have undergone ABO-nonidentical orthotopic liver transplantation (OLT). Yet, until now, little was known about the management of this transplantation-induced hemolysis. In this report we describe our experience with hemolysis in a patient after OLT. In addition, based on theoretical assumption, we hypothesize that corticosteroids can be helpful in the management of ABO-nonidentical OLT-induced hemolysis.
authors.affiliation: Department of Internal Medicine, Ikazia Hospital, Rotterdam, The Netherlands.
authors.forename: J J
authors.initials: JJ
authors.lastname: Auwerda
authors.forename: D J
authors.initials: DJ
authors.lastname: Bac
authors.forename: M B
authors.initials: MB
authors.lastname: van't Veer
authors.forename: S
authors.initials: S
authors.lastname: de Rave
authors.forename: J N
authors.initials: JN
authors.lastname: Yzermans
mesh_terms: D000017:ABO Blood-Group System / Q000276:immunology*; D019264:Adoptive Transfer; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000743:Anemia, Hemolytic / Q000188:drug therapy / Q000209:etiology*; D000888:Antibodies, Anti-Idiotypic / Q000276:immunology*; D001402:B-Lymphocytes / Q000276:immunology / Q000637:transplantation; D001787:Blood Group Incompatibility / Q000188:drug therapy / Q000209:etiology*; D001803:Blood Transfusion; D006084:Graft Rejection / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008099:Liver / Q000166:cytology / Q000276:immunology; D016031:Liver Transplantation / Q000009:adverse effects* / Q000276:immunology; D008297:Male; D008875:Middle Aged; D014184:Transplantation, Homologous / Q000009:adverse effects
chemical_list: D000017:ABO Blood-Group System; D000305:Adrenal Cortex Hormones; D000888:Antibodies, Anti-Idiotypic; D007166:Immunosuppressive Agents