title: Cutaneous T-cell lymphoma, tropical spastic paraparesis, cerebral vasculitis, and protein S deficiency in a patient with HTLV-I.
abstract: The clinical spectrum of retroviruses is expanding rapidly. Human T-cell lymphotropic virus type I (HTLV-I) was the first retrovirus to be described, and its role had been established in adult T-cell leukemia/lymphoma and tropical spastic paraparesis. We report the case of a 35-year-old woman with HTLV-I and the unusual combination of cutaneous T-cell lymphoma, tropical spastic paraparesis, cerebral vasculitis, and protein S deficiency. We discuss the relationship of all her diseases to HTLV-I.
authors.affiliation: Department of Internal Medicine, Morristown Memorial Hospital, NJ 07960-1956, USA.
authors.forename: J
authors.initials: J
authors.lastname: Schwartz
authors.forename: J
authors.initials: J
authors.lastname: Gonzalez
authors.forename: R
authors.initials: R
authors.lastname: Rosenberg
authors.forename: K
authors.initials: K
authors.lastname: Fujihara
authors.forename: C M
authors.initials: CM
authors.lastname: Cottrill
authors.forename: A S
authors.initials: AS
authors.lastname: Klainer
authors.forename: E
authors.initials: E
authors.lastname: Bisaccia
mesh_terms: D000328:Adult; D002543:Cerebral Hemorrhage / Q000150:complications; D002561:Cerebrovascular Disorders / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D015490:HTLV-I Infections / Q000150:complications*; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000150:complications*; D015493:Paraparesis, Tropical Spastic / Q000150:complications*; D018455:Protein S Deficiency / Q000150:complications*; D012878:Skin Neoplasms / Q000150:complications*; D013924:Thrombophlebitis / Q000150:complications; D014657:Vasculitis / Q000150:complications*