title: The metabolic distinctiveness of emulsified lipid particles in the bloodstream and its clinical implications.
abstract: The advantages of administering intravenous fat emulsions are well known. Primarily, they are important sources of essential fatty acids; they allow the administration of many calories within a small volume; and they are isotonic compared to body fluid. In this review, the metabolic distinctiveness of parenterally infused fat particles in the bloodstream is evaluated under four main headings: (1) the structure and metabolism of fat emulsion particles; (2) the metabolism of phospholipid-rich fat emulsion; (3) the interactions between fat emulsion particles and plasma lipoproteins; and (4) the acquisition of protein moieties (apolipoproteins) by fat emulsion particles and its clinical implications.
authors.affiliation: Second Department of Surgery, Mie University School of Medicine, Tsu, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Iriyama
mesh_terms: D001053:Apolipoproteins / Q000502:physiology; D002914:Chylomicrons / Q000378:metabolism; D005217:Fat Emulsions, Intravenous / Q000378:metabolism* / Q000627:therapeutic use; D006801:Humans; D010288:Parenteral Nutrition
chemical_list: D001053:Apolipoproteins; D002914:Chylomicrons; D005217:Fat Emulsions, Intravenous