Eosinophilic pustular folliculitis (Ofuji disease) in a child.
Eosinophilic pustular folliculitis (EPF) has been described mostly in adults from Japan. From the few reports of children with EPF it is clear that the disease displays the characteristic features, with some clinical differences compared to EPF in adults. We describe the case of an 8-year-old boy with multiple vesicles, pustules, and erythema multiforme-like lesions on the trunk and lower extremities. Results of histopathologic examination revealed subcorneal and intraepidermal pustules, and an inflammatory infiltrate consisting of lymphocytes and eosinophils mainly with a perifollicular distribution. The patient also had impaired chemotaxis, IgG3 subclass deficiency, and elevated IgE levels.
Lazarov
A
A
Dermatological Clinic, Sapir Medical Center, Meir General Hospital, Kfar Saba, Israel.
Wolach
B
B
Cordoba
M
M
Abraham
D
D
Vardy
D
D
D017668:Age of Onset; D001707:Biopsy, Needle; D002648:Child; D003937:Diagnosis, Differential; D004802:Eosinophilia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D005499:Folliculitis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D008297:Male; D012872:Skin Diseases, Vesiculobullous / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy