Genetics of movement disorders.
Trinucleotide repeat expansions or unstable mutations are the cause of a growing number of hereditary movement disorders, especially inherited ataxias. Diagnostic practice as well as disease classifications have altered accordingly. Genes responsible for "Parkinsonian plus' syndromes and episodic movement disorders have also been recently mapped.
Dürr
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INSERM U289 and Fédération de Neurologie, Hôpital de la Salpêtriere, Paris, France.
Brice
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D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D004252:DNA Mutational Analysis; D005838:Genotype; D006801:Humans; D009069:Movement Disorders / Q000145:classification / Q000175:diagnosis / Q000235:genetics*; D010302:Parkinson Disease, Secondary / Q000145:classification / Q000175:diagnosis / Q000235:genetics; D010641:Phenotype; D013132:Spinocerebellar Degenerations / Q000145:classification / Q000175:diagnosis / Q000235:genetics; D018911:Trinucleotide Repeats / Q000235:genetics