title: Mechanical ventilation in obstructive lung disease.
abstract: This article reviews selected topics relevant to the use of mechanical ventilation in patients with severe airflow obstruction. Areas discussed include the bedside assessment of respiratory system mechanics, the ventilatory determinants of dynamic pulmonary hyperinflation, the role of controlled hypoventilation with permissive hypercapnia, and the delivery of bronchodilators during mechanical ventilation.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, University of Minnesota Medical School, Minneapolis, USA.
authors.forename: J W
authors.initials: JW
authors.lastname: Leatherman
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000403:Airway Resistance; D001993:Bronchodilator Agents / Q000627:therapeutic use; D006801:Humans; D006935:Hypercapnia / Q000628:therapy; D008173:Lung Diseases, Obstructive / Q000628:therapy*; D008176:Lung Volume Measurements; D011175:Positive-Pressure Respiration; D012121:Respiration, Artificial / Q000009:adverse effects; D015656:Respiratory Mechanics
chemical_list: D000305:Adrenal Cortex Hormones; D001993:Bronchodilator Agents