title: Malignant hyperthermia in a 3-month-old infant: a case report.
abstract: First described in 1960, malignant hyperthermia (MH) is a relatively rare disorder of muscle metabolism triggered by specific anesthetic agents and presenting as a rapidly evolving intraoperative crisis. The syndrome is more prevalent among children (1/15,000 exposures to anesthesia) than adults (1/50,000 exposures), but has not been thought to occur in children younger than 1 year of age. This is a case report of a 3-month-old, 4.85 kg white male infant who developed MH while undergoing repair of a right inguinal hernia. The case is unique not only with respect to the age of the patient but also with the extremely elevated creatine phosphokinase (CPK) 13 hours postoperatively.
authors.forename: G P
authors.initials: GP
authors.lastname: Pennington
authors.forename: L
authors.initials: L
authors.lastname: Joeris
mesh_terms: D003402:Creatine Kinase / Q000032:analysis; D006552:Hernia, Inguinal / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D007223:Infant; D007431:Intraoperative Complications / Q000503:physiopathology*; D008297:Male; D008305:Malignant Hyperthermia / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
chemical_list: D003402:Creatine Kinase