[Systematic lymphadenectomy in stomach carcinoma--staging and therapy].
The diagnostic and therapeutic relevance of systematic (D2-) lymphadenectomy was studied in 440 resections for primary gastric carcinoma. A total of 13910 lymph nodes (mean: 31.6 (15.3)) was resected with 3716 being metastatic (mean: 8.6 (11.0)). During surgery 24% of the carcinomas were incorrectly staged when compared with the pathological stage. The prognosis was influenced by tumor stage, R-classification and number of lymph node metastases. Patients with a maximum of three metastases and R0-resection had a prognosis not significantly different from patients with pN0-stage (5-year-survival: 77% and 64% resp.; p = 0.21). Systematic lymphadenectomy in gastric carcinoma has not only diagnostic, but also therapeutic importance in patients with limited lymph node metastases.
Jähne
J
J
Klinik für Abdominal- und Transplantationschirurgie, Medizinische Hochschule Hannover.
Maschek
H
H
Meyer
H J
HJ
Pichlmayr
R
R
D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000368:Aged; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery; D015996:Survival Rate