title: Unique and conserved features of Tula hantavirus M gene encoding envelope glycoproteins G1 and G2.
abstract: The sequence of the genomic M segment encoding the surface glycoproteins G1 and G2 of wild-type Tula hantavirus (TUL) has been determined. Analyses of M nucleotide sequences show that TUL is genetically distinct from other hantaviruses. Comparison to ten currently known hantavirus G1G2 amino acid sequences points out several, presumably functional, regions with substantial homology indicating a common ancestry and similar evolutionary pathways for all members of the Hantavirus genus.
authors.affiliation: Haartman Institute, Department of Virology, University of Helsinki, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Plyusnin
authors.forename: Y
authors.initials: Y
authors.lastname: Cheng
authors.forename: H
authors.initials: H
authors.lastname: Lehväslaiho
authors.forename: A
authors.initials: A
authors.lastname: Vaheri
mesh_terms: D000595:Amino Acid Sequence; D017124:Conserved Sequence; D006476:Orthohantavirus / Q000235:genetics*; D008969:Molecular Sequence Data; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D016415:Sequence Alignment; D014759:Viral Envelope Proteins / Q000737:chemistry / Q000235:genetics*
chemical_list: D014759:Viral Envelope Proteins; C104008:glycoprotein G1, Hantavirus; C090197:glycoprotein G2, Hantavirus