Cerebral vasculitis following allopurinol treatment.
A 45-year-old man developed cerebral vasculitis associated with a systemic hypersensitivity response shortly after commencing treatment with allopurinol. The illness settled on withdrawal of the drug and no other cause was found.
Rothwell
P M
PM
Department of Clinical Neurosciences, Western General Hospital, Edinburgh, UK.
Grant
R
R
D000493:Allopurinol / Q000009:adverse effects*; D002561:Cerebrovascular Disorders / Q000139:chemically induced; D004342:Drug Hypersensitivity; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy; D008224:Lymphoma, Follicular / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D014657:Vasculitis / Q000139:chemically induced*; D014969:Xanthine Oxidase / Q000037:antagonists & inhibitors*
D004791:Enzyme Inhibitors; D000493:Allopurinol; D014969:Xanthine Oxidase