title: The non-Langerhans' cell histiocytoses in childhood.
abstract: The cutaneous histiocytoses are best divided in the Langerhans' cell histiocytoses and non-Langerhans' cell histiocytoses. In the former group, the cells react with S100 and CD1a antibodies, while in the latter group they express a variety of macrophage markers. Xanthogranuloma is a frequent childhood tumor and the only common non-Langerhans' cell histiocytosis. Xanthogranulomas contain a mixture of several different types of histiocytes that also appear in more pure forms as both solitary tumors and disseminated processes. The varying histiocyte morphology provides a unifying concept for non-Langerhans' cell histiocytoses.
authors.affiliation: Department of Dermatology, Ludwig Maximilian University, Munich, Germany.
authors.forename: W H
authors.initials: WH
authors.lastname: Burgdorf
authors.forename: B
authors.initials: B
authors.lastname: Zelger
mesh_terms: D000328:Adult; D002648:Child; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology; D015614:Histiocytosis / Q000151:congenital / Q000473:pathology; D015616:Histiocytosis, Non-Langerhans-Cell / Q000473:pathology*; D006801:Humans; D012871:Skin Diseases / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology; D014972:Xanthogranuloma, Juvenile / Q000473:pathology