title: [A cross-sectional study of factors associated with production of Japanese cedar pollen specific IgE antibody and total IgE antibody, and symptoms of Japanese cedar pollinosis in primary school children].
abstract: Frequency of and factors associated with sensitization by Japanese cedar pollen (JCP) and Japanese cedar pollinosis (JCPS) were analyzed by a cross-sectional method. Four hundred and five primary school children in a rural town were examined by a questionnaire filled out by their parents and a serum test in May, 1994. Children with positive JCP specific IgE antibody (CAP-RAST score > = 1) comprised 39%, and those with a score of 2 or more, 35%. Prevalence of JCPS defined as positive IgE antibody and "definite symptoms" (any nasal and/or conjunctival symptom continuing for three weeks or more in March and/or April) was 8%, and that of JCPS defined as positive IgE antibody and "definite or possible symptoms" (no condition for duration) was 22%. Children with a high total IgE antibody level (> = 250 U/ml) comprised 26%. The JCP specific IgE antibody level revealed a strong positive correlation with the total IgE antibody level. Past and family history of allergic disease in general was associated with a total IgE antibody level stronger than the JCP specific IgE antibody level, and the history was also associated with allergic-like symptoms except for JCPS stronger than the symptoms of JCPS. Passive smoking by family and use of kerosene stove were negatively associated with the highest level of JCP specific IgE antibody and was not associated with other levels. One explanation may be that allergic disposition influences smoking habits, but the unique condition of nasal mucosa for allergic reaction should be considered.
authors.affiliation: Department of Preventive Medicine, Kyoto Prefectural University of Medicine.
authors.forename: K
authors.initials: K
authors.lastname: Ozasa
authors.forename: H
authors.initials: H
authors.lastname: Takenaka
authors.forename: N
authors.initials: N
authors.lastname: Takagi
authors.forename: A
authors.initials: A
authors.lastname: Aoike
mesh_terms: D000906:Antibodies / Q000097:blood; D000917:Antibody Formation; D002648:Child; D003430:Cross-Sectional Studies; D006361:Heating; D006801:Humans; D007073:Immunoglobulin E / Q000096:biosynthesis* / Q000097:blood; D011058:Pollen / Q000276:immunology*; D006255:Rhinitis, Allergic, Seasonal / Q000209:etiology / Q000276:immunology*; D014028:Tobacco Smoke Pollution
chemical_list: D000906:Antibodies; D014028:Tobacco Smoke Pollution; D007073:Immunoglobulin E