title: The surgical management of patients with glomus tumours of the skull base.
abstract: Total surgical excision is the only treatment modality that offers a cure for patients with glomus tumours of the skull base. The vascularity, inaccessibility and frequently extensive local spread, all contribute to the difficulties encountered in the management of patients with these complex lesions. Owing to the rarity of skull base glomus tumours, experience in their management can only be attained over long periods of time. We describe the surgical management of 20 patients with large glomus tumours of the skull base treated by an otoneurosurgical team over an 11-year period. Overall, 70% of patients had an excellent outcome, 10% a good outcome and 20% a poor outcome at a mean follow-up of 3.1 years. Poor outcomes were due to severe facial nerve palsies in two cases, and poorly accommodated palsies of the bulbar cranial nerves in a further two patients. The management of postoperative neurological deficits is discussed in detail. We conclude that in the majority of patients with skull base glomus tumours, complete surgical excision can be safely achieved.
authors.affiliation: Department of Otoneurosurgery, Addenbrooke's NHS Trust, Cambridge, UK.
authors.forename: P C
authors.initials: PC
authors.lastname: Whitfield
authors.forename: P
authors.initials: P
authors.lastname: Grey
authors.forename: D G
authors.initials: DG
authors.lastname: Hardy
authors.forename: D A
authors.initials: DA
authors.lastname: Moffat
mesh_terms: D000328:Adult; D000368:Aged; D002533:Cerebral Angiography; D005918:Glomus Tumor / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011183:Postoperative Complications; D012189:Retrospective Studies; D019291:Skull Base / Q000473:pathology / Q000601:surgery*; D019292:Skull Base Neoplasms / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome