[At what concentration should albumin be prescribed?].
Human albumin is available either as a 4 or a 20% solution. Only the latter is a plasma expander which increases volaemia by an amount corresponding to the four-fold of the infused volume. In addition, the sodium load by the latter per gramme of albumin is five times lower as both solutions have the same sodium content. Therefore, when the administration of albumin is indicated, the 20% solution should be preferred, as well as for volume expansion as for other uses, due to a decreased sodium load. However, this recommendation has not been substantiated by comparative studies.
Mantz
J
J
Département d'anesthésie et de réanimation chirurgicale, hôpital Bichat, Paris, France.
D000418:Albumins / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D009994:Osmolar Concentration; D009997:Osmotic Pressure; D010953:Plasma Volume / Q000187:drug effects*; D012964:Sodium / Q000097:blood
D000418:Albumins; D012964:Sodium