title: Evaluation of 1-(9-anthracenylmethyl) piperazine for the analysis of isocyanates in spray-painting operations.
abstract: A new reagent, 1-(9-anthracenylmethyl)piperzine (MAP), was used for the derivatization of airborne 1,6-hexamethylene diisocyanate (HDI) and polyisocyanates generated during spray-painting operations. The new reagent, which offers enhanced sensitivity and uniformity of response to both the monomeric and oligomeric forms of HDI, was compared directly with 1-(2-methoxyphenyl)piperazine (MOP), the currently employed derivatizing reagent used in the National Institute for Occupational Safety and Health Method 5521. Both the validity of the side-by-side sampling protocol and the efficacy of two derivatizing reagents were evaluated in field studies. The analytical results indicate that there is no significant difference at the 95% confidence level in the concentration of polyisocyanate in the aerosol as determined by two impingers containing MAP and a third containing MOP when these are positioned in a side-by-side-by-side arrangement.
authors.affiliation: Department of Chemistry, Southwest Texas State University, San Marcos 78666, USA.
authors.forename: W E
authors.initials: WE
authors.lastname: Rudzinski
authors.forename: S
authors.initials: S
authors.lastname: Norman
authors.forename: B
authors.initials: B
authors.lastname: Dahlquist
authors.forename: K W
authors.initials: KW
authors.lastname: Greebon
authors.forename: A
authors.initials: A
authors.lastname: Richardson
authors.forename: K
authors.initials: K
authors.lastname: Locke
authors.forename: T
authors.initials: T
authors.lastname: Thomas
mesh_terms: D000395:Air Pollutants, Occupational / Q000032:analysis*; D000873:Anthracenes / Q000737:chemistry; D003485:Cyanates / Q000032:analysis*; D004784:Environmental Monitoring / Q000379:methods* / Q000592:standards; D006801:Humans; D017953:Isocyanates; D009314:National Institute for Occupational Safety and Health, U.S.; D010150:Paint; D010879:Piperazines / Q000737:chemistry; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014481:United States
chemical_list: C103443:1-(9-anthracenylmethyl)piperazine; D000395:Air Pollutants, Occupational; D000873:Anthracenes; D003485:Cyanates; D017953:Isocyanates; D010879:Piperazines; C015262:1,6-hexamethylene diisocyanate