Liver involvement in familial granulomatous arthritis (Blau syndrome).
We describe hepatic granulomata in a patient with familial granulomatous synovitis (Blau syndrome). While visceral involvement is a previously unrecognized manifestation of Blau syndrome, its occurrence has been well documented in a similar disease, childhood sarcoidosis. Our findings suggest that the 2 conditions (Blau syndrome and childhood sarcoidosis) are more closely related than thought.
Saini
S K
SK
Department of Pediatrics, Alfred I duPont Institute, Wilmington, Delaware, USA.
Rose
C D
CD
D000328:Adult; D001168:Arthritis / Q000150:complications* / Q000235:genetics; D002675:Child, Preschool; D003286:Contracture / Q000150:complications; D005260:Female; D005385:Fingers; D005799:Genes, Dominant; D006099:Granuloma / Q000150:complications* / Q000235:genetics; D006801:Humans; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000150:complications* / Q000473:pathology; D008297:Male; D013577:Syndrome; D013583:Synovial Membrane / Q000473:pathology