Mapping of unconventional myosins in mouse and human.
Myosins are molecular motors that move along filamentous actin. Seven classes of myosin are expressed in vertebrates: conventional myosin, or myosin-II, as well as the 6 unconventional myosin classes-I, -V, -VI, -VII, -IX, and -X. We have mapped in mouse 22 probes encompassing all known unconventional myosins and, as a result, have identified 16 potential unconventional myosin genes. These genes include 7 myosins-I, 2 myosins-V, 1 myosin-VI, 3 myosins-VII, 2 myosins-IX, and 1 myosin-X. The map location of 5 of these genes was identified in human chromosomes by fluorescence in situ hybridization.
Hasson
T
T
Department of Biology, Yale University, New Haven, Connecticut 06520, USA.
Skowron
J F
JF
Gilbert
D J
DJ
Avraham
K B
KB
Perry
W L
WL
Bement
W M
WM
Anderson
B L
BL
Sherr
E H
EH
Chen
Z Y
ZY
Greene
L A
LA
Ward
D C
DC
Corey
D P
DP
Mooseker
M S
MS
Copeland
N G
NG
Jenkins
N A
NA
D000818:Animals; D002874:Chromosome Mapping; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008969:Molecular Sequence Data; D009218:Myosins / Q000235:genetics*
D009218:Myosins