title: [Primary granulocytic sarcoma of the pancreas: efficacy of early treatment with intensive chemotherapy].
abstract: In the absence of systemic chemotherapy after the diagnosis of primary granulocytic sarcoma (PGS), all patients will subsequently develop acute myelogenous leukemia (AML). The authors describe a case of PGS of the head of the pancreas found at laparotomy in a 32-year-old man. The patient received early after surgery, two courses of high-dose chemotherapy and, with a follow-up of 2 years, never developed AML. This rare observation illustrates the necessity of further early systemic chemotherapy after surgical excision of PGS.
authors.affiliation: Service d'hématologie clinique, CHU Hôtel-Dieu, Nantes, France.
authors.forename: P
authors.initials: P
authors.lastname: Moreau
authors.forename: N
authors.initials: N
authors.lastname: Milpied
authors.forename: O
authors.initials: O
authors.lastname: Thomas
authors.forename: M
authors.initials: M
authors.lastname: Fiche
authors.forename: V
authors.initials: V
authors.lastname: Parys
authors.forename: J
authors.initials: J
authors.lastname: Paineau
authors.forename: J P
authors.initials: JP
authors.lastname: Dutin
authors.forename: J L
authors.initials: JL
authors.lastname: Harousseau
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D006801:Humans; D007951:Leukemia, Myeloid / Q000188:drug therapy*; D008297:Male; D010190:Pancreatic Neoplasms / Q000188:drug therapy*; D013997:Time Factors