title: Deep cerebral invasion by basal cell carcinoma of the scalp.
abstract: We report recurrent basal cell carcinoma of the scalp with deep cerebral invasion in an 82-year-old man. Plain films and CT showed extensive, full thickness, skull destruction at the vertex. Gadolinium-enhanced MRI revealed neoplastic invasion of the meninges and left cerebral hemisphere, down to the lateral ventricle. We postulate that tumour extended into the brain along perivascular spaces of transcerebral vessels. This hypothesis is supported by the cleft-like contrast enhancement on MRI.
authors.affiliation: Department of Radiology, University of Antwerp (Universitair Ziekenhuis Antwerpen, Edegem, Belgium.
authors.forename: P M
authors.initials: PM
authors.lastname: Parizel
authors.forename: L
authors.initials: L
authors.lastname: Dirix
authors.forename: D
authors.initials: D
authors.lastname: Van den Weyngaert
authors.forename: J R
authors.initials: JR
authors.lastname: Lambert
authors.forename: P
authors.initials: P
authors.lastname: Scalliet
authors.forename: A T
authors.initials: AT
authors.lastname: Van Oosterom
authors.forename: A M
authors.initials: AM
authors.lastname: De Schepper
mesh_terms: D000368:Aged; D001921:Brain / Q000473:pathology / Q000528:radiation effects; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000532:radiotherapy; D002280:Basal Cell Carcinoma / Q000175:diagnosis* / Q000532:radiotherapy; D016371:Cranial Irradiation; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D012535:Scalp / Q000473:pathology* / Q000528:radiation effects; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000532:radiotherapy