title: Non-invasive functional mapping with multi-channel near infra-red spectroscopic topography in humans.
abstract: Near-infrared spectroscopy (NIRS) is a new technique for non-invasive monitoring of tissue oxygenation and its kinetics. Up to this date, it has been used solely in research for the global hemodynamic change of the brain and for rough regional activation after stimulating the brain physiologically. This paper describes functional brain mapping using multi channel (ten channel) NIRS by applying the motor stimulation in humans. Our results demonstrate that the regional hemodynamic change was detected in a small area around the motor cortex with a time resolution of 1-2 s. NIRS technique offers considerable potential for research and clinical applications with no invasion.
authors.affiliation: Department of Neurosurgery, Tokyo Metropolitan Police Hospital, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Watanabe
authors.forename: Y
authors.initials: Y
authors.lastname: Yamashita
authors.forename: A
authors.initials: A
authors.lastname: Maki
authors.forename: Y
authors.initials: Y
authors.lastname: Ito
authors.forename: H
authors.initials: H
authors.lastname: Koizumi
mesh_terms: D000328:Adult; D001931:Brain Mapping; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009044:Motor Cortex / Q000502:physiology*; D013055:Spectrophotometry, Infrared; D013997:Time Factors