Cutaneous T-cell lymphoma, tropical spastic paraparesis, cerebral vasculitis, and protein S deficiency in a patient with HTLV-I.
The clinical spectrum of retroviruses is expanding rapidly. Human T-cell lymphotropic virus type I (HTLV-I) was the first retrovirus to be described, and its role had been established in adult T-cell leukemia/lymphoma and tropical spastic paraparesis. We report the case of a 35-year-old woman with HTLV-I and the unusual combination of cutaneous T-cell lymphoma, tropical spastic paraparesis, cerebral vasculitis, and protein S deficiency. We discuss the relationship of all her diseases to HTLV-I.
Schwartz
J
J
Department of Internal Medicine, Morristown Memorial Hospital, NJ 07960-1956, USA.
Gonzalez
J
J
Rosenberg
R
R
Fujihara
K
K
Cottrill
C M
CM
Klainer
A S
AS
Bisaccia
E
E
D000328:Adult; D002543:Cerebral Hemorrhage / Q000150:complications; D002561:Cerebrovascular Disorders / Q000150:complications*; D005260:Female; D005500:Follow-Up Studies; D015490:HTLV-I Infections / Q000150:complications*; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000150:complications*; D015493:Paraparesis, Tropical Spastic / Q000150:complications*; D018455:Protein S Deficiency / Q000150:complications*; D012878:Skin Neoplasms / Q000150:complications*; D013924:Thrombophlebitis / Q000150:complications; D014657:Vasculitis / Q000150:complications*