Effect of selection for lifetime production of lamb weaned on hormonal factors that affect growth in Targhee ewes and lambs.
Targhee ewes (n = 22, average age 5 yr) rearing twin lambs were used to investigate serum growth hormone (GH), IGF-I, triiodothyronine (T3), thyroxine (T4), and prolactin (PRL; ewes only) concentrations associated with selection pressure for lifetime production of kilograms of lamb weaned per ewe. Period 1 started on d 4 after birth and was conducted in confinement. Periods 2, 3, and 4 were conducted on fenced intermountain sagebrush-bunchgrass range starting at an average of 49, 84, and 112 d after birth, respectively. Blood samples were collected hourly for 6 h on d 4, 11, 18, 25, 49, 84, and 112 after lambing. Ewe models included the fixed effect for line, with ewe age, lambing date, and starting weight nested within line as potential covariables. Lamb models included fixed effects for line, sex, and sibling sex, with lamb age and birth weight nested within line tested as possible covariables. Growth hormone concentrations were greater (P = .06) for selected than for control ewes, but lamb GH concentrations did not differ (P = .90) between selected and control lambs. Ewe prolactin concentration tended (P = .13) to be greater for control than selected ewes. Ewe and lamb IGF-I did not differ (P > .55) between selected and control ewes and lambs. Ewe T3 and T4 concentrations did not differ (P > .19) between selected and control ewes; however, lamb T3 and T4 concentrations were greater (P < .01) for control than for selected lambs. Increased GH concentration in selected ewes seemed to be associated with greater milk production. Differences in selected and control lamb T3 and T4 concentrations could be an indicator of receptor sensitivity, metabolic activity, or seasonal reproductive transitions in ewe lambs.
Head
W A
WA
New Mexico State University, Las Cruces 88003, USA.
Hatfield
P G
PG
Hallford
D M
DM
Fitzgerald
J A
JA
Petersen
M K
MK
Stellflug
J N
JN
D000375:Aging / Q000097:blood*; D000818:Animals; D001724:Birth Weight; D005260:Female; D005298:Fertility / Q000502:physiology; D013006:Growth Hormone / Q000097:blood*; D007334:Insulin-Like Growth Factor I / Q000032:analysis*; D008297:Male; D011388:Prolactin / Q000097:blood*; D012621:Seasons; D012641:Selection, Genetic; D012756:Sheep / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism*; D013974:Thyroxine / Q000097:blood*; D013997:Time Factors; D014284:Triiodothyronine / Q000097:blood*
D014284:Triiodothyronine; D007334:Insulin-Like Growth Factor I; D011388:Prolactin; D013006:Growth Hormone; D013974:Thyroxine