title: Tumors arising in the palpebral lobe of the lacrimal gland.
abstract: OBJECTIVE
  Tumors arising in the palpebral lobe of the lacrimal gland are uncommon. There have been only eight reported patients, all of whom had pleomorphic adenomas. The authors present another six patients with primary palpebral lobe tumors.
  
  
  METHODS
  The clinical presentation, computed tomographic, and pathologic findings of these six patients were reviewed.
  
  
  RESULTS
  Tumor types include three pleomorphic adenomas, one well-differentiated adenoid cystic carcinoma, one carcinoma in pleomorphic adenoma, and one carcinoma ex pleomorphic adenoma. All six patients presented with a painless mass in the upper outer eyelid without significant displacement of the globe, but the superficial location of these lesions led to early detection. The tumors were localized to the lacrimal gland, predominantly anterior to the orbital rim. In all six patients, the involved palpebral lobe was removed, five via a direct anterior subcutaneous approach and one by superolateral orbitotomy. In two patients (adenoid cystic carcinoma and carcinoma ex pleomorphic adenoma), repeat surgery via superolateral orbitotomy was necessary to achieve complete removal of the lacrimal gland and surrounding tissue. No recurrences were detected during follow-up (range, 6 months to 7 years; mean, 26 months).
  
  
  CONCLUSIONS
  Palpebral lobe tumors of the lacrimal gland are more common and consist of a greater variety of histologic types than previously described. In our series, these tumors comprise 17% of all epithelial lacrimal gland lesions. These are the first reported cases of malignancy in this location. A longer follow-up period is necessary to determine the true recurrence rate of these tumors.
authors.affiliation: Department of Ophthalmology, Vancouver Hospital & Health Sciences Centre, University of British Columbia, Canada.
authors.forename: S
authors.initials: S
authors.lastname: Vangveeravong
authors.forename: S E
authors.initials: SE
authors.lastname: Katz
authors.forename: J
authors.initials: J
authors.lastname: Rootman
authors.forename: V
authors.initials: V
authors.lastname: White
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D008949:Adenoma, Pleomorphic / Q000473:pathology* / Q000601:surgery; D000328:Adult; D000368:Aged; D003528:Carcinoma, Adenoid Cystic / Q000473:pathology* / Q000601:surgery; D005142:Eyelid Neoplasms / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007766:Lacrimal Apparatus Diseases / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed