[Anesthesia for cesarean section: drug transfer to fetus during anesthesia].
One case of prenatally diagnosed congenital diaphragmatic hernia was reviewed in terms of the anesthetic managements. Concentrations of diazepam, pancuronium and fentanyl were measured in maternal, fetal and umbilical serum. As expectedly, the transition of diazepam through the placenta was large and the concentration of diazepam in the fetal serum was equal to that of maternal serum, but only a small amount of pancuronium was transferred.
Higashi
T
T
Department of Anesthesiology, Kure Kyosai Hospital.
Kamo
N
N
Naitou
H
H
Tada
K
K
D000328:Adult; D000773:Anesthesia, Obstetrical; D018686:Anesthetics, Intravenous / Q000097:blood; D002585:Cesarean Section; D003975:Diazepam / Q000097:blood; D005260:Female; D005283:Fentanyl / Q000097:blood; D005315:Fetal Diseases / Q000175:diagnosis; D006548:Hernia, Diaphragmatic / Q000175:diagnosis; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D008431:Maternal-Fetal Exchange; D003473:Neuromuscular Nondepolarizing Agents / Q000097:blood; D010197:Pancuronium / Q000097:blood; D011247:Pregnancy; D011296:Prenatal Diagnosis
D018686:Anesthetics, Intravenous; D003473:Neuromuscular Nondepolarizing Agents; D010197:Pancuronium; D003975:Diazepam; D005283:Fentanyl