title: Growth characteristics of the human nasal septum.
abstract: Using a specially designed algorithm for the measurement of the surface area of shapes with highly irregular contours, growth curves were developed for post-natal septal growth in humans using post-mortem specimens of a study population of 30 cases, distributed over the age range from birth to 62 years. From the results a rapid growth phase for the total septum is evident immediately after birth, lasting until the second year of life. Then, a gradual deceleration of growth is recognized with a plateau eventually being reached at the age of 36 years. Mathematical analysis of the growth curve shows that the curve for the total septum is the sum of two separate mathematical equations, representing the cartilaginous and bony contribution, respectively. It is demonstrated that the cartilaginous septum reaches adult dimensions (lateral surface area) at the age of two years. Subsequent growth of the septum is due to expansion of the perpendicular plate, i.e. the bony parts of the septum.
authors.affiliation: Department of Otorhinolaryngology, University Hospital Dijkzigt, Rotterdam, The Netherlands.
authors.forename: J
authors.initials: J
authors.lastname: Van Loosen
authors.forename: G A
authors.initials: GA
authors.lastname: Van Zanten
authors.forename: C V
authors.initials: CV
authors.lastname: Howard
authors.forename: H L
authors.initials: HL
authors.lastname: Verwoerd-Verhoef
authors.forename: D
authors.initials: D
authors.lastname: Van Velzen
authors.forename: C D
authors.initials: CD
authors.lastname: Verwoerd
mesh_terms: D000293:Adolescent; D000328:Adult; D000465:Algorithms; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009300:Nasal Septum / Q000033:anatomy & histology / Q000254:growth & development*