Recurrence of a choroidal neovascular membrane in a patient with punctate inner choroidopathy treated with daily doses of thalidomide.
OBJECTIVE
To determine whether thalidomide therapy can prevent a recurrence of a choroidal neovascular membrane in a patient with punctate inner choroidopathy.


METHODS
Case report. In a 38-year-old woman with bilateral punctate inner choroidopathy, thalidomide therapy was initiated three days after laser photocoagulation of a choroidal neovascular membrane.


RESULTS
The patient had a recurrence of the choroidal neovascular membrane eight months after the start of thalidomide therapy.


CONCLUSIONS
The failure of thalidomide to prevent a recurrence of a choroidal neovascular membrane in this patient suggests that this medication may have only a limited benefit in preventing recurrences of choroidal neovascular membranes.
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Department of Ophthalmology, University of Pittsburgh School of Medicine, PA, USA.
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D000328:Adult; D002829:Choroid / Q000098:blood supply* / Q000187:drug effects; D015862:Choroid Diseases / Q000150:complications*; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D017075:Laser Coagulation; D009389:Neovascularization, Pathologic / Q000209:etiology* / Q000628:therapy; D012008:Recurrence; D013792:Thalidomide / Q000627:therapeutic use*
D007166:Immunosuppressive Agents; D013792:Thalidomide