Local antibiotic prophylaxis in surgery.
The perioperative use of antibiotics is an established and accepted technique for the prevention of postoperative infection. Intravenous administration often is preferred, and intramuscular administration is possible, although it has certain drawbacks. This article examines a variety of other routes of administration for delivering antibiotics locally to the surgical site. These techniques merit further study in prospectively randomized trials.
Martin
C
C
Department of Anesthesia, Intensive Care and Traumatology, Hôpital Nord, France.
Viviand
X
X
Potié
F
F
D019072:Antibiotic Prophylaxis / Q000379:methods; D004333:Drug Administration Routes; D016503:Drug Delivery Systems; D006801:Humans; D013514:Surgical Procedures, Operative / Q000592:standards*; D013530:Surgical Wound Infection / Q000517:prevention & control*