Abnormal colonic accumulation of fluorine-18-FDG in pseudomembranous colitis.
A 51-yr-old man with a history of pancreatic carcinoma was studied with [18F]fluorodeoxyglucose ([18F]FDG) and PET as part of staging for residual disease after chemotherapy. The PET study was performed during a clostridium difficile-associated diarrheal illness. Striking [18F]FDG uptake was demonstrated in the wall of the colon over its entire length. Clostridium difficile associated diarrhea and mechanisms of [18F]FDG uptake in normal and abnormal tissues are briefly reviewed and a mechanism for FDG uptake in this patient is postulated.
Hannah
A
A
Department of Nuclear Medicine, Ludwig Institute for Cancer Research, Austin Hospital, Heidelberg, Victoria, Australia.
Scott
A M
AM
Akhurst
T
T
Berlangieri
S
S
Bishop
J
J
McKay
W J
WJ
D003106:Colon / Q000000981:diagnostic imaging*; D003847:Deoxyglucose / Q000031:analogs & derivatives*; D004761:Enterocolitis, Pseudomembranous / Q000150:complications / Q000000981:diagnostic imaging*; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy; D011877:Radionuclide Imaging
D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D003847:Deoxyglucose