Thyrotropin receptor antibodies in parotid saliva.
Parotid saliva was collected with a Carlson-Crittenden device, under citric acid stimulation, in 18 patients with autoimmune thyroid disease. Thyrotropin Receptor Antibodies (TRAb) were measured with a radioreceptor assay in parotid saliva and in serum in the same patients, and a statistical analysis of the data was performed. TRAb levels in parotid saliva were higher than in serum in the 3 pathologies studied (Graves' disease, Hashitoxicosis and Hashimoto's thyroiditis). There was good correlation between salivary and serum levels.
Tumilasci
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OR
Department of Physiology, Faculty of Medicine, University of Buenos Aires, Argentina.
Arqueros
M C
MC
Ostuni
M A
MA
el Tamer
E
E
Houssay
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AB
D001323:Autoantibodies / Q000032:analysis* / Q000097:blood / Q000276:immunology; D001327:Autoimmune Diseases / Q000209:etiology* / Q000276:immunology; D006111:Graves Disease / Q000209:etiology / Q000276:immunology; D006801:Humans; D010306:Parotid Gland / Q000378:metabolism*; D011869:Radioligand Assay; D011989:Receptors, Thyrotropin / Q000276:immunology*; D012463:Saliva / Q000276:immunology* / Q000378:metabolism; D013967:Thyroiditis, Autoimmune / Q000209:etiology / Q000276:immunology; D013971:Thyrotoxicosis / Q000209:etiology / Q000276:immunology; D013972:Thyrotropin / Q000032:analysis / Q000378:metabolism
D001323:Autoantibodies; D011989:Receptors, Thyrotropin; D013972:Thyrotropin