qValue--a program to calculate comparative measures of genomic reorganisation from cytogenetic and/or linkage information.
A program qValue, which calculates a measure of the genomic reorganisation that has occurred between pairs of species since their divergence from a common ancestor, is described. The program takes a tab-delimited text file containing data describing the location of various genetic loci in multiple species and generates an output text file, also in tab-delimited format, that lists various parameters of genomic reorganisation between all possible pairs of species considered. This provides a useful tool for the developing field of comparative genome mapping, particularly in the study of the evolution of the vertebrate genome.
Law
A S
AS
Division of Molecular Biology, Roslin Institute (Edinburgh), Midlothian, Scotland. Andy.Law@bbsrc.ac.uk
Burt
D W
DW
D000818:Animals; D005075:Biological Evolution; D002874:Chromosome Mapping; D003582:Cytogenetics; D008040:Genetic Linkage; D005821:Genetic Techniques; D006801:Humans; D012984:Software; D013045:Species Specificity; D014714:Vertebrates / Q000235:genetics