Randomization in clinical trials and experimental molecular medicine.
Randomization has become a standard procedure for clinical trial design, and is also widely used in other areas of biological research. This article will examine the reasons why randomization has become a sine qua non in some areas, yet remains far less widely adopted in experimental studies of molecular medicine. Should randomization be used routinely in the design of most laboratory experiments?
Fayers
P M
PM
Medical Research Council Cancer Trials Office, Cambridge, UK. pfayers@mrc-cto.cam.ac.uk
D015982:Bias; D006801:Humans; D007434:Intrauterine Devices; D018579:Patient Selection; D016032:Randomized Controlled Trials as Topic / Q000706:statistics & numerical data