Hormesis in effect of low uranium doses on organisms.
Uranium nitrate applied daily in small amounts per os (0.5-17 mg/l in drinking water) or per cuttim (0.2-0.8 g/kg) exerts positive effect on metabolism of phosphate ions by red blood cells in vitro. This positive effect changes to the negative one with increasing dose or exposure time. It may be assumed that most other cells in the organism are affected in the same way as erythrocytes and that similar effect might be observed with other harmful agents or substances.
Prokes
J
J
Institute for Toxicology and Forensic Chemistry, Charles University, Praha, Czech Republic.
Haas
T
T
Sromová
S
S
Jojková
K
K
Vulterin
K
K
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D004912:Erythrocytes / Q000378:metabolism / Q000528:radiation effects; D066298:In Vitro Techniques; D010710:Phosphates / Q000097:blood; D051381:Rats; D014502:Uranyl Nitrate / Q000008:administration & dosage / Q000633:toxicity*
D010710:Phosphates; D014502:Uranyl Nitrate