Effect of hydrocortisone succinate on growth of Chlamydia pneumoniae in vitro.
We examined the effect of hydrocortisone succinate on the growth of three isolates of Chlamydia pneumoniae in vitro. There was a significant increase in the number of inclusions seen in two of the C. pneumoniae strains in the presence of hydrocortisone. There was no significant increase in the number of inclusions with various concentrations of hydrocortisone over time. The addition of hydrocortisone did not affect the in vitro activities of azithromycin, erythromycin, and doxycycline against C. pneumoniae.
Tsumura
N
N
Department of Pediatrics, State University of New York Health Science Center at Brooklyn 11203-2098, USA.
Emre
U
U
Roblin
P
P
Hammerschlag
M R
MR
D016993:Chlamydophila pneumoniae / Q000187:drug effects* / Q000254:growth & development; D006854:Hydrocortisone / Q000031:analogs & derivatives* / Q000494:pharmacology
C007133:hydrocortisone hemisuccinate; D006854:Hydrocortisone