A case of total peripheral aneosinophilia associated with complete deficiency of myeloperoxidase.
Complete and permanent absence of peripheral eosinophilic granulocytes was observed in a patient also presenting with total myeloperoxidase deficiency. The anomaly was suspected because of complete absence of the eosinophilic cluster in the display of a H*3 Technicon hematological automate and was confirmed by traditional staining of more than 100,000 leukocytes. A severe infectious problem during adolescence could be related to MPO deficiency in this patient. No specific disorder attributable to aneosinophilia was however observed subsequently.
Muller-Hagedorn
S
S
Department des Sciences, Centre Universitaire de Luxembourg, Luxembourg.
Forges
T
T
Kutter
D
D
Conrad
R
R
D000368:Aged; D004804:Eosinophils / Q000473:pathology; D006801:Humans; D007970:Leukopenia / Q000150:complications*; D008297:Male; D008661:Metabolism, Inborn Errors / Q000150:complications*; D009195:Peroxidase / Q000172:deficiency*
D009195:Peroxidase