title: Effect of extracorporeal shock wave lithotripsy on prostate specific antigen.
abstract: OBJECTIVE
  We evaluated the effects of extracorporeal shock wave lithotripsy (ESWL) of distal ureteral calculi on serum prostate specific antigen (PSA).
  
  
  METHODS
  A total of 29 consecutive men with distal ureteral calculi at a maximum of 25 mm. from the ureteral orifice, and without any history of urinary tract infection, benign prostatio hyperplasia or prostate cancer underwent ESWL with the Dornier MPL 9000 X lithotriptor. The therapeutic focus size was 48 X 7 mm. PSA was measured exactly 5 minutes before ESWL, as well as 120 minutes, 24 hours and 7 days after termination of treatment.
  
  
  RESULTS
  Fragmentation rate was 100% and all patients were stone-free within 1 week of therapy. There was no statistically significant difference between PSA values before and after treatment. Only 15 patients had a slight increase in PSA at 120 minutes after treatment (range 0.01 to 0.41 ng./ml., mean 0.07).
  
  
  CONCLUSIONS
  ESWL can be performed in men at risk for prostate cancer without impairing the predictive value of PSA.
authors.affiliation: Universitätsklinik für Urologie, Karl-Franzens-Universität Graz, Austria.
authors.forename: T
authors.initials: T
authors.lastname: Colombo
authors.forename: R
authors.initials: R
authors.lastname: Zigeuner
authors.forename: S
authors.initials: S
authors.lastname: Altziebler
authors.forename: K
authors.initials: K
authors.lastname: Pummer
authors.forename: H
authors.initials: H
authors.lastname: Stettner
authors.forename: G
authors.initials: G
authors.lastname: Hubmer
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008096:Lithotripsy; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood*; D014514:Ureteral Calculi / Q000097:blood* / Q000628:therapy*
chemical_list: D017430:Prostate-Specific Antigen