title: Radioiodine treatment of thyroid carcinoma in patients on maintenance hemodialysis.
abstract: To deliver optimal radioiodine activity in hemodialyzed patients with thyroid carcinoma, the behavior of radioiodine was followed during six treatments. During hemodialysis, blood activity decreases with a half-life of 3.4 +/- 0.5, (1SD) h. The whole body dose was calculated from the total activity determined during 10 days after 131I administration. A reasonable strategy may consist in delivering 25% of the currently prescribed activity (925 MBq-25 mCi) and to perform the first dialysis session after 24 h to reduce total body irradiation.
authors.affiliation: Department of Endocrinology, Cliniques Universitaires St. Luc, Brussels, Belgium.
authors.forename: C
authors.initials: C
authors.lastname: Daumerie
authors.forename: S
authors.initials: S
authors.lastname: Vynckier
authors.forename: J
authors.initials: J
authors.lastname: Caussin
authors.forename: M
authors.initials: M
authors.lastname: Jadoul
authors.forename: J P
authors.initials: JP
authors.lastname: Squifflet
authors.forename: N
authors.initials: N
authors.lastname: de Patoul
authors.forename: A
authors.initials: A
authors.lastname: Wambersie
mesh_terms: D000328:Adult; D002291:Carcinoma, Papillary / Q000150:complications* / Q000532:radiotherapy*; D017809:Fatal Outcome; D005260:Female; D006084:Graft Rejection / Q000503:physiopathology; D006801:Humans; D006978:Hypertension, Renovascular / Q000150:complications; D007457:Iodine Radioisotopes / Q000097:blood / Q000627:therapeutic use; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D016030:Kidney Transplantation / Q000502:physiology; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009362:Neoplasm Metastasis; D016035:Pancreas Transplantation / Q000502:physiology; D011829:Radiation Dosage; D006435:Renal Dialysis; D013964:Thyroid Neoplasms / Q000150:complications* / Q000532:radiotherapy*; D013965:Thyroidectomy; D014915:Whole-Body Counting
chemical_list: D007457:Iodine Radioisotopes