title: Gallbladder opacification 12-24 h after angiography by CT examination: a multivariate analysis.
abstract: BACKGROUND
  To examine the incidence and predisposing factors of gallbladder opacification in delayed computed tomography (CT) after angiography.
  
  
  METHODS
  CT examination 12-24 h after angiography was performed in 389 patients. Univariate and multivariate analyses were made.
  
  
  RESULTS
  Two hundred thirty-three of 389 patients (60%) revealed gallbladder opacification. Type of contrast medium (P < 0. 01), total bilirubin (P < 0.01), and serum creatinine (P < 0.01) were significant and independent factors relating to gallbladder opacification. Ioxaglate (70%, relative odds = 2.86) and iohexol (63%, relative odds = 2.03) showed higher gallbladder opacification rates than that of iopamidol (45%, relative odds = 1.43) and diatrizoate (30%). Patients with a lower serum bilirubin level (relative odds = 1.67) and a raised serum creatinine level (relative odds = 2.01) showed higher incidence of gallbladder opacification.
  
  
  CONCLUSIONS
  Gallbladder opacification after angiography is not an abnormal finding on delayed CT in patients with not only abnormal renal function but also normal hepatobiliary and normal renal function, especially for modern contrast media.
authors.affiliation: Department of Radiation Oncology, Biomedical Research Center, Osaka University Medical School, Yamadaoka 2-2, Suita Osaka, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yamazaki
authors.forename: H
authors.initials: H
authors.lastname: Oi
authors.forename: M
authors.initials: M
authors.lastname: Matsushita
authors.forename: T
authors.initials: T
authors.lastname: Teshima
authors.forename: S
authors.initials: S
authors.lastname: Murayama
authors.forename: T
authors.initials: T
authors.lastname: Nose
authors.forename: T
authors.initials: T
authors.lastname: Koizumi
authors.forename: E
authors.initials: E
authors.lastname: Tanaka
mesh_terms: D000792:Angiography; D001663:Bilirubin / Q000097:blood; D015984:Causality; D003287:Contrast Media; D003404:Creatinine / Q000097:blood; D005260:Female; D005704:Gallbladder / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012737:Sex Factors; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media; D003404:Creatinine; D001663:Bilirubin