title: Good clinical outcome in a patient with a large CT scan hypodensity treated with intra-arterial urokinase after an embolic stroke.
abstract: Hypodense regions demonstrated by CT within 6 hours of the onset of stroke may reflect irreversibly damaged tissue, and some have suggested that patients with such findings should be spared the risks of thrombolytic therapy since they are unable to benefit from it. We report here a patient with a low-density area demonstrated by CT less than 6 hours after onset of symptoms who improved dramatically after successful intra-arterial thrombolysis.
authors.affiliation: Department of Neurological Surgery, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
authors.forename: R
authors.initials: R
authors.lastname: Tarr
authors.forename: C L
authors.initials: CL
authors.lastname: Taylor
authors.forename: W R
authors.initials: WR
authors.lastname: Selman
authors.forename: J S
authors.initials: JS
authors.lastname: Lewin
authors.forename: D
authors.initials: D
authors.lastname: Landis
mesh_terms: D002533:Cerebral Angiography; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology*; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D014057:Tomography, X-Ray Computed; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D014568:Urokinase-Type Plasminogen Activator