title: Predictors of outcome in malarial renal failure.
abstract: We studied 38 patients with acute renal failure (ARF) due to malaria over a 5-year period between 1990 and 1994 at the Institute of Urology and Transplantation. There were 30 males and 8 females who ranged in age from 13 to 75 years. Most were critically ill on presentation with blood urea levels between 116 and 587 mg% and serum creatinine concentrations between 3 and 30 mg%. Anemia accompanied by hyperbilirubinemia was a result of severe hemolysis. Antimalarial therapy consisted of quinine sulfate, chloroquine, or both. Of the 38 patients, 32 required hemodialysis and eventually recovered normal (n = 29) or near normal (n = 3) function. Six patients died.
authors.affiliation: Sindh Institute of Urology and Transplantation Civil Hospital, Dow Medical College Karachi, Pakistan.
authors.forename: R
authors.initials: R
authors.lastname: Naqvi
authors.forename: E
authors.initials: E
authors.lastname: Ahmad
authors.forename: F
authors.initials: F
authors.lastname: Akhtar
authors.forename: I
authors.initials: I
authors.lastname: Yazdani
authors.forename: K
authors.initials: K
authors.lastname: Abbas
authors.forename: A
authors.initials: A
authors.lastname: Naqvi
authors.forename: A
authors.initials: A
authors.lastname: Rizvi
mesh_terms: D058186:Acute Kidney Injury / Q000378:metabolism / Q000469:parasitology* / Q000628:therapy; D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use; D003404:Creatinine / Q000097:blood; D005260:Female; D006417:Hematuria / Q000150:complications / Q000652:urine; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D016778:Malaria, Falciparum / Q000150:complications* / Q000469:parasitology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010963:Plasmodium falciparum / Q000302:isolation & purification; D011379:Prognosis; D011507:Proteinuria / Q000150:complications / Q000652:urine; D006435:Renal Dialysis; D012189:Retrospective Studies; D014508:Urea / Q000097:blood
chemical_list: D000962:Antimalarials; D006454:Hemoglobins; D014508:Urea; D003404:Creatinine