Immunologic cytofluorometric studies in adolescents with anorexia nervosa.
OBJECTIVE
To assess lymphocyte stimulation and lymphocyte phenotype evaluation in adolescent patients with anorexia nervosa (AN).


METHODS
In vitro lymphocyte stimulation and flow cytometric phenotype studies were done on 26 hospitalized patients with AN receiving nutritional rehabilitation. The laboratory assessment consisted of lymphocyte subset analysis and in vitro lymphoproliferative responses to mitogens and antigens.


RESULTS
Flow cytometric phenotype analysis showed that only a minority of the patients had abnormal phenotype and immune responses, moreover their immune systems were not significantly impaired.


CONCLUSIONS
The cytofluorometric study of immune function does not show significant alterations in adolescents hospitalized for anorexia nervosa.
Silber
T J
TJ
George Washington University School of Medicine and Health Sciences, Washington, D.C.
Chan
M
M
D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000276:immunology*; D002648:Child; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D016130:Immunophenotyping; D008213:Lymphocyte Activation / Q000276:immunology*; D012016:Reference Values; D016176:T-Lymphocyte Subsets / Q000276:immunology*