Assays for antibodies to varicella-zoster virus.
Anti-varicella-zoster virus serum antibody assays and their use in vaccine development are described. Of particular interest are FAMA and neutralization assays and the gpELISA. These and other assays are compared and summarized in terms of characteristics including biologic relevance, sensitivity, specificity, and suitability for different laboratory and clinical applications.
Krah
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Department of Virus and Cell Biology, Merck Research Laboratories, West Point, Pennsylvania, USA.
D000914:Antibodies, Viral / Q000032:analysis* / Q000276:immunology; D000956:Antigens, Viral / Q000276:immunology; D002644:Chickenpox / Q000276:immunology / Q000517:prevention & control / Q000821:virology; D003429:Cross Reactions; D004797:Enzyme-Linked Immunosorbent Assay; D014645:Herpesvirus 3, Human / Q000276:immunology*; D006801:Humans
D000914:Antibodies, Viral; D000956:Antigens, Viral