title: Measurement of blood flow with radiolabeled microspheres in reflected mucogingival flaps in cats.
abstract: To quantify and compare blood flow in maxillary mucogingival flaps, a total of 16 cats (32 mucogingival specimens) were divided into two groups. In group I the blood flow in attached or reflected maxillary tissues were measured. In Group II the effects on blood flow were measured in reflected tissues after the injection of the following solutions: (1) saline solution; (2) 2% lidocaine plain; (3) 2% lidocaine with 1:50,000 epinephrine; (4) no injection. After an injection of 153 Gadolinium microspheres into the left ventricle of the heart, the tissues were harvested and placed in a gamma counter. Group I had a mean blood flow value of 34.4 ml/min/100 gm of tissue for the unreflected samples and 152.3 ml/min/100 gm of reflected tissue. The levels of blood flow in tissue samples in group II results were: no injection (control), 41.2 ml/min/100 gm; saline solution, 46.8 ml/min/110 gm; 2% lidocaine with 1:50,000 epinephrine, 60.6 ml/min/100 gm; and 2% lidocaine plain, 90.2 ml/min/100 gm. On the basis of these results it appears that reflection of gingival tissue and injection of 2% lidocaine plain induces increased blood flow 90 minutes postoperatively.
authors.affiliation: School of Dentistry, Loma Linda University, Calif, USA.
authors.forename: G T
authors.initials: GT
authors.lastname: Wuchenich
authors.forename: M
authors.initials: M
authors.lastname: Torabinejad
authors.forename: R D
authors.initials: RD
authors.lastname: Gilbert
authors.forename: P
authors.initials: P
authors.lastname: McMillan
mesh_terms: D000318:Adrenergic beta-Agonists / Q000494:pharmacology; D000704:Analysis of Variance; D000779:Anesthetics, Local / Q000494:pharmacology; D000818:Animals; D001783:Blood Flow Velocity; D001810:Blood Volume / Q000187:drug effects*; D001811:Blood Volume Determination / Q000379:methods*; D002415:Cats; D004338:Drug Combinations; D004837:Epinephrine / Q000494:pharmacology; D005682:Gadolinium; D005881:Gingiva / Q000098:blood supply*; D008012:Lidocaine / Q000494:pharmacology; D008863:Microspheres; D011868:Radioisotopes; D012039:Regional Blood Flow / Q000187:drug effects; D018709:Statistics, Nonparametric; D013524:Surgical Flaps / Q000098:blood supply; D014662:Vasoconstrictor Agents / Q000494:pharmacology; D014665:Vasodilator Agents / Q000494:pharmacology
chemical_list: D000318:Adrenergic beta-Agonists; D000779:Anesthetics, Local; D004338:Drug Combinations; D011868:Radioisotopes; D014662:Vasoconstrictor Agents; D014665:Vasodilator Agents; D008012:Lidocaine; D005682:Gadolinium; D004837:Epinephrine