title: Blood cell markers.
abstract: Cytochemistry and immunocytochemistry are important adjunctive technologies to the morphologic characterization of blood cells and hematopoietic neoplasms. Although cytochemistry is briefly discussed, the emphasis of this article is on the clinical application of flow cytometry and leukocyte monoclonal antibodies in veterinary medicine. Classification and significance of immunophenotyping in canine and feline lymphomas and immunodeficiencies such as feline immunodeficiency virus and feline leukemia virus are discussed.
authors.affiliation: Department of Microbiology, Pathology, and Parasitology, College of Veterinary Medicine, North Carolina State University, Raleigh, USA.
authors.forename: C B
authors.initials: CB
authors.lastname: Grindem
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000032:analysis / Q000276:immunology; D015415:Biomarkers / Q000032:analysis*; D001773:Blood Cells / Q000276:immunology* / Q000473:pathology*; D002371:Cat Diseases / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D002415:Cats; D004283:Dog Diseases / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D004285:Dogs; D005434:Flow Cytometry / Q000379:methods / Q000592:standards / Q000662:veterinary; D019337:Hematologic Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary; D007150:Immunohistochemistry / Q000379:methods / Q000592:standards; D016130:Immunophenotyping / Q000379:methods / Q000592:standards / Q000662:veterinary; D007938:Leukemia / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary; D007962:Leukocytes / Q000276:immunology / Q000473:pathology; D008223:Lymphoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary; D011785:Quality Assurance, Health Care; D011786:Quality Control
chemical_list: D000911:Antibodies, Monoclonal; D015415:Biomarkers