Distribution and characterisation of the [3H](S)-zacopride labelled 5-HT3 receptor in pig forebrain.
The present study demonstrates the presence and distribution of [3H](S)-zacopride labelled 5-HT3 (5-hydroxytryptamine3) receptors in pig forebrain. The pharmacological characterisation of 5-HT3 receptor recognition sites in homogenates of pig cerebral cortex provides further evidence for inter-species variation in the pharmacology of the 5-HT3 receptor.
Fletcher
S
S
Department of Pharmacology, The Medical School, University of Birmingham, Edgbaston, UK. s.fletcher@bham.ac.uk
Barnes
N M
NM
D000818:Animals; D001549:Benzamides / Q000494:pharmacology*; D001667:Binding, Competitive; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D016548:Prosencephalon / Q000187:drug effects / Q000378:metabolism*; D011985:Receptors, Serotonin / Q000187:drug effects*; D012702:Serotonin Antagonists / Q000494:pharmacology*; D013552:Swine
D001549:Benzamides; D019086:Bridged Bicyclo Compounds, Heterocyclic; D011985:Receptors, Serotonin; D012702:Serotonin Antagonists; C055971:zacopride