Use of thrombospondin level to predict the clinical course of atopic dermatitis associated with food hypersensitivity or skin infection.
Plasma thrombospondin (TSP) levels were monitored in patients with atopic dermatitis (AD) exacerbated by food hypersensitivity (FH) or skin infection. In both groups, the TSP levels correlated positively with skin disease severity score from the onset to 2 months after treatment. A sustained TSP level above 250 ng/ml predicted a 7-fold increase in the incidence of flare-up of AD.
Huang
S W
SW
Department of Pediatrics, Allergy/Immunology, University of Florida College of Medicine, Gainesville 32610-0296, USA.
Kao
K J
KJ
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000150:complications* / Q000503:physiopathology*; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications*; D005544:Forecasting; D006801:Humans; D007223:Infant; D008297:Male; D008562:Membrane Glycoproteins / Q000097:blood*; D012044:Regression Analysis; D012720:Severity of Illness Index; D012874:Skin Diseases, Infectious / Q000150:complications*; D019699:Thrombospondins
D008562:Membrane Glycoproteins; D019699:Thrombospondins