title: Dermatolactone, a cytotoxic fungal sesquiterpene with a novel skeleton.
abstract: The nematicidal 5-pentyl-2-furaldehyde and the cytotoxic sesquiterpene dermatolactone were isolated from the extracts of an Ascomycete belonging to the Dermateaceae. The furan has previously been reported from the Basidiomycete Irpex lacteus, while dermatolactone is a new compound the structure of which was determined by spectrosocpic methods.
authors.affiliation: Lehrbereich Biotechnologie der Universität Kaiserslautern, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Mayer
authors.forename: B
authors.initials: B
authors.lastname: Köpke
authors.forename: H
authors.initials: H
authors.lastname: Anke
authors.forename: O
authors.initials: O
authors.lastname: Sterner
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D000969:Antinematodal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity*; D001487:Basidiomycota; D017173:Caenorhabditis elegans; D006094:Gram-Positive Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000633:toxicity*
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000969:Antinematodal Agents; D012717:Sesquiterpenes; C102123:dermatolactone