title: Clinical management of nonhealing periradicular pathosis. Surgery versus endodontic retreatment.
abstract: OBJECTIVE
  This prospective randomized study compared the outcome of retreatment and surgical intervention in root canal treated teeth with nonhealing periradicular pathosis.
  
  
  METHODS
  One such tooth from each of 38 patients was randomly allotted to retreatment or root-end resection and root-end filling. Treatment outcome after 1 year was evaluated and compared clinically and radiographically.
  
  
  RESULTS
  The success rate for surgery was higher than for conventional retreatment, but the difference was not statistically significant.
  
  
  CONCLUSIONS
  For management of nonhealing periradicular pathosis associated with root canal treated teeth, surgical intervention should be considered as an alternative to retreatment. In cases with a similar prognosis for both modes of treatment, the choice should be governed by consideration of intrinsic and extrinsic factors.
authors.affiliation: Department of Endodontics, Karolinska Institutet, Huddinge University Hospital, Sweden.
authors.forename: J
authors.initials: J
authors.lastname: Danin
authors.forename: T
authors.initials: T
authors.lastname: Strömberg
authors.forename: H
authors.initials: H
authors.lastname: Forsgren
authors.forename: L E
authors.initials: LE
authors.lastname: Linder
authors.forename: L O
authors.initials: LO
authors.lastname: Ramsköld
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001047:Apicoectomy; D016009:Chi-Square Distribution; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010483:Periapical Diseases / Q000601:surgery / Q000628:therapy*; D011446:Prospective Studies; D019233:Retreatment; D012184:Retrograde Obturation; D012389:Root Canal Obturation; D019553:Tooth, Nonvital; D016896:Treatment Outcome; D014945:Wound Healing