title: Studies on the enhancement of the reactivity of the (Cys-25)-S-/(His159)-Im+H ion-pair of papain by deprotonation across pKa 4.
authors.affiliation: Department of Biochemistry, Queen Mary & Westwield College, University of London, U.K.
authors.forename: S
authors.initials: S
authors.lastname: Pinitglang
authors.forename: M
authors.initials: M
authors.lastname: Noble
authors.forename: C
authors.initials: C
authors.lastname: Verma
authors.forename: E W
authors.initials: EW
authors.lastname: Thomas
authors.forename: K
authors.initials: K
authors.lastname: Brocklehurst
mesh_terms: D001665:Binding Sites; D003545:Cysteine / Q000737:chemistry; D006639:Histidine / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007477:Ions; D007700:Kinetics; D015394:Molecular Structure; D010206:Papain / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D007477:Ions; D006639:Histidine; D010206:Papain; D003545:Cysteine