title: Genetic variation in Australian Merino sheep.
abstract: Variation at 22 gene loci was investigated in a flock of Australian Merino sheep using restriction fragment length polymorphism (RFLP) analysis. Polymorphism was observed at 20 loci, including loci for wool keratin, hormone and immunoglobulin light chain genes. Eleven loci yielded unambiguous genotypes suitable for population data analysis. Average heterozygosity, determined from these and two monomorphic loci, was estimated as 0.107 (SE = 0.024). Average heterozygosity excluding all monomorphic data as estimated at 0.377 (SE = 0.031), which is comparable with human RFLP heterozygosities for loci chosen in the same way that we selected sheep loci.
authors.affiliation: School of Biological Sciences, Macquarie University, New South Wales, Australia.
authors.forename: Y M
authors.initials: YM
authors.lastname: Parsons
authors.forename: D W
authors.initials: DW
authors.lastname: Cooper
authors.forename: L R
authors.initials: LR
authors.lastname: Piper
mesh_terms: D000818:Animals; D001315:Australia; D005819:Genetic Markers; D014644:Genetic Variation; D005838:Genotype; D006579:Heterozygote; D006728:Hormones / Q000235:genetics; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000235:genetics; D007633:Keratins / Q000235:genetics; D012150:Polymorphism, Restriction Fragment Length; D015183:Restriction Mapping; D012756:Sheep / Q000235:genetics*; D014935:Wool
chemical_list: D005819:Genetic Markers; D006728:Hormones; D007147:Immunoglobulin Light Chains; D007633:Keratins