Gliomatosis cerebri. Results with radiation therapy.
BACKGROUND
This review was undertaken to determine the outcome for patients diagnosed in the modern era and treated with radiation therapy.


METHODS
Using the tumor registries of six institutions in a large metropolitan area, cases of gliomatosis were identified and retrospectively reviewed.


RESULTS
The clinical course for each patient was unique. Deterioration during treatment, brief stabilization, and reversal of the clinical signs and symptoms with stability and high quality of life at 16 months from diagnosis characterized Patients 1, 2, and 3, respectively.


CONCLUSIONS
Radiotherapy for gliomatosis appears to stabilize or improve neurologic function in some patients. Its impact on survival will await additional reports and longer follow-up.
Cozad
S C
SC
Therapeutic Radiologists, Inc., Kansas City, Missouri 64132, USA.
Townsend
P
P
Morantz
R A
RA
Jenny
A B
AB
Kepes
J J
JJ
Smalley
S R
SR
D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000473:pathology / Q000503:physiopathology / Q000532:radiotherapy*; D005260:Female; D005910:Glioma / Q000473:pathology / Q000503:physiopathology / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D011788:Quality of Life; D012042:Registries; D012189:Retrospective Studies