Diabetes mellitus in Kearns-Sayre syndrome: a case with a 10-year follow-up.
An 11-year-old girl with Kearns-Sayre Syndrome developed diabetes mellitus with ketoacidosis at onset and immediate insulin-requirement. In a 10-year follow-up, while neuromuscular disease was progressively increasing, diabetes was well controlled by once-a-day insulin therapy. Insulin secretion appears low, but without impairment during the years. This case points out the diabetes' features in Kearns-Sayre syndrome.
Franzese
A
A
Department of Pediatrics, University Federico II, Naples, Italy.
Del Giudice
E
E
Santoro
L
L
De Filippo
G
G
Argenziano
A
A
D017668:Age of Onset; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007004:Hypoglycemic Agents / Q000494:pharmacology / Q000627:therapeutic use; D007328:Insulin / Q000494:pharmacology / Q000627:therapeutic use; D007625:Kearns-Sayre Syndrome / Q000150:complications / Q000503:physiopathology*
D007004:Hypoglycemic Agents; D007328:Insulin