Cyclic peptides from higher plants. 24.1 yunnanin C, a novel cyclic heptapeptide from Stellaria yunnanensis.
A novel cytotoxic cyclic heptapeptide, yunnanin C (1), was isolated from the roots of Stellaria yunnanensis. The structure of 1, cyclo(-Gly-Ile-Gly-Phe-Tyr-Ser-Pro-), was elucidated from spectroscopic evidence and by chemical degradation.
Morita
H
H
Department of Pharmacognosy, Tokyo University of Pharmacy and Life Science, Japan.
Kayashita
T
T
Shimomura
M
M
Takeya
K
K
Itokawa
H
H
D000595:Amino Acid Sequence; D000596:Amino Acids / Q000737:chemistry; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification* / Q000494:pharmacology; D002681:China; D004354:Drug Screening Assays, Antitumor; D007941:Leukemia P388 / Q000188:drug therapy; D051379:Mice; D008969:Molecular Sequence Data; D010456:Peptides, Cyclic / Q000302:isolation & purification* / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011487:Protein Conformation
D000596:Amino Acids; D000972:Antineoplastic Agents, Phytogenic; D010456:Peptides, Cyclic; C102704:yunnanin C