Factors affecting renal allograft survival in African Americans.
African Americans are more likely to develop end-stage renal disease than other racial groups. Although transplantation is optimal therapy for most end-stage renal disease patients, many potential black recipients do not have ready access to cadaveric kidneys. Following transplantation, blacks are at increased risk of allograft loss as a result of the interaction of multiple immunologic and nonimmunologic factors.
Gaston
R S
RS
Department of Medicine, University of Alabama at Birmingham 35294, USA.
D001741:Black or African American; D044383:Black People / Q000235:genetics; D004198:Disease Susceptibility; D006084:Graft Rejection / Q000208:ethnology / Q000235:genetics / Q000276:immunology / Q000517:prevention & control; D006085:Graft Survival / Q000276:immunology; D006648:Histocompatibility; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000208:ethnology; D007165:Immunosuppression Therapy; D007676:Kidney Failure, Chronic / Q000208:ethnology / Q000601:surgery; D016030:Kidney Transplantation / Q000276:immunology / Q000706:statistics & numerical data; D015999:Multivariate Analysis; D012307:Risk Factors; D012959:Socioeconomic Factors; D016896:Treatment Outcome