title: Risk factors of tracheostomal recurrence after laryngectomy for laryngeal carcinoma.
abstract: BACKGROUND
  Tracheostomal recurrence after total laryngectomy for laryngeal carcinoma has a poor prognosis. The independent risk factors of tracheostomal recurrence are, however, not well documented.
  
  
  METHODS
  This is a multivariate analysis of the risk factors of tracheostomal recurrence after total laryngectomy for 322 laryngeal squamous cell carcinomas. The factors included in the analysis were sex, age, tumor stage, sites of tumor involvement, preoperative airway obstruction, preoperative tracheostomy, extent of surgical resection, radiotherapy, and pathological resection margin.
  
  
  RESULTS
  Seventeen (5%) patients developed tracheostomal recurrence. Univariate analysis showed that preoperative airway obstruction, subglottic involvement, and postcricoid extension were significant factors associated with tracheostomal recurrence. Multivariate analysis using logistic regression method showed that both subglottic and postcricoid involvement were independent predisposing factors for tracheostomal recurrence. The tracheostomal recurrence rates were 2% in patients without the risk factor and 10% in patients with the presence of one or both risk factors.
  
  
  CONCLUSIONS
  Subglottic and postcricoid involvement were independent risk factors for tracheostomal recurrence.
authors.affiliation: Department of Surgery, University of Hong Kong, Queen Mary Hospital, Hong Kong.
authors.forename: A P
authors.initials: AP
authors.lastname: Yuen
authors.forename: W I
authors.initials: WI
authors.lastname: Wei
authors.forename: W K
authors.initials: WK
authors.lastname: Ho
authors.forename: Y
authors.initials: Y
authors.lastname: Hui
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D012307:Risk Factors; D014139:Tracheostomy