The translation initiation factor eIF4A from Schizosaccharomyces pombe is closely related to its mammalian counterpart.
We have isolated a cDNA clone encoding eIF4A from Schizosaccharomyces pombe. The deduced protein sequence is similar in length and sequence to other eIF4A proteins and exhibits highest similarity with the mammalian eIF4A protein. Hybridization with genomic DNA reveals two eIF4A genes located on two different chromosomes.
Fischli
A
A
Department of Microbiology, University Basel, Switzerland.
Schmid
S R
SR
Coppolecchia
R
R
Linder
P
P
D000595:Amino Acid Sequence; D000818:Animals; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics; D039601:Eukaryotic Initiation Factor-4A; D005800:Genes, Fungal / Q000235:genetics; D008322:Mammals; D008969:Molecular Sequence Data; D010448:Peptide Initiation Factors / Q000235:genetics*; D012568:Schizosaccharomyces / Q000235:genetics*; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
D018076:DNA, Complementary; D010448:Peptide Initiation Factors; D039601:Eukaryotic Initiation Factor-4A