title: Ultrasound-guided neurosurgery: a feasibility study in the 3-30 MHz frequency range.
abstract: This study, which includes seven patients, illustrates some potential values of the interactive use of ultrasound technology prior to, during and after brain tumour resection. Ultrasound B-scan and colour flow imaging were applied during open surgery using a cardiac scanner in the 3.25-7.5 MHz frequency range and an intravascular scanner with catheters at 10, 20 and 30 MHz. The tumour and vital blood vessels were localized prior to resection using low frequency imaging from the brain surface. High frequency, high resolution close-up imaging was applied during and after resection in order to identify remaining tumour tissue, as well as to detect blood vessels in the vicinity of the resection wall. The study also demonstrates that the tumour and surgical tools such as, for example, bipolar diathermy, acoustic aspirator or biopsy forceps,can be visualized simultaneously. This simplifies the localization of remaining tumour tissue.
authors.affiliation: Sinted Unimed, Trondheim, Norway aageg@unimed.sintef.no
authors.forename: A
authors.initials: A
authors.lastname: Gronningsaeter
authors.forename: G
authors.initials: G
authors.lastname: Unsgard
authors.forename: S
authors.initials: S
authors.lastname: Ommedal
authors.forename: B A
authors.initials: BA
authors.lastname: Angelsen
mesh_terms: D000328:Adult; D000368:Aged; D001254:Astrocytoma / Q000098:blood supply / Q000000981:diagnostic imaging / Q000601:surgery; D001783:Blood Flow Velocity / Q000502:physiology; D001932:Brain Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging / Q000556:secondary / Q000601:surgery*; D004453:Echoencephalography / Q000295:instrumentation*; D004867:Equipment Design; D005260:Female; D005909:Glioblastoma / Q000098:blood supply / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D008297:Male; D008577:Meningeal Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging / Q000601:surgery; D008579:Meningioma / Q000098:blood supply / Q000000981:diagnostic imaging / Q000601:surgery; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000295:instrumentation; D012039:Regional Blood Flow / Q000502:physiology; D012680:Sensitivity and Specificity; D013238:Stereotaxic Techniques / Q000295:instrumentation*; D018615:Ultrasonography, Doppler, Color / Q000295:instrumentation*; D017585:Ultrasonography, Doppler, Transcranial / Q000295:instrumentation*