[Myoglobinuria following anesthesia with enflurane and succinylcholine in an asthmatic child on theophylline].
An 8-year-old asthmatic child on theophylline was anesthetized with enflurane in nitrous oxide and oxygen. He developed a generalized muscle rigidity after intravenous succinylcholine. Although the maximum rectal temperature was 37.9 degrees C, a marked elevation in muscle-derived enzymes and myoglobinuria were observed. The relations among theophylline which is a derivative of xanthines, inhalation anesthetics, and myoglobinuria are discussed.
Shono
S
S
Department of Anesthesiology, Fukuoka University, School of Medicine.
Higa
K
K
Watanabe
R
R
Dan
K
K
D000769:Anesthesia, Inhalation / Q000009:adverse effects*; D001249:Asthma / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D002648:Child; D004737:Enflurane; D006801:Humans; D008297:Male; D009127:Muscle Rigidity / Q000209:etiology; D009212:Myoglobinuria / Q000209:etiology*; D009467:Neuromuscular Depolarizing Agents / Q000009:adverse effects*; D009609:Nitrous Oxide; D010100:Oxygen; D013390:Succinylcholine / Q000009:adverse effects*; D013806:Theophylline / Q000627:therapeutic use*
D001993:Bronchodilator Agents; D009467:Neuromuscular Depolarizing Agents; D004737:Enflurane; D013806:Theophylline; D013390:Succinylcholine; D009609:Nitrous Oxide; D010100:Oxygen