title: Organizational structure and communication strategies of the bypass angioplasty revascularization investigation: a multicenter clinical trial.
abstract: Efficient communication is a challenge for the many operating components of a multicenter randomized clinical trial. Traditional management theory states that communications generally flow along a path established by a hierarchical organizational structure. A multicenter clinical trial does not fit traditional organizational models well and requires modification of traditional communication techniques. While the scientific community typically views a clinical trial as one large and cohesive enterprise, at each site the trial may actually be conducted as a small project related to the medical specialty of the investigator. Therefore overall trial management must be accomplished through collaboration rather than through direct management. In the Bypass Angioplasty Revascularization Investigation (BARI), the BARI clinical coordinating center has designed and utilized several mechanisms that facilitate effective communication and administrative control of a multicenter clinical trial. These mechanisms provide a framework of communication techniques that accommodate the specific needs of a complex organization.
authors.affiliation: BARI Clinical Coordinating Center, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15261, USA.
authors.forename: B L
authors.initials: BL
authors.lastname: Naydeck
authors.forename: K
authors.initials: K
authors.lastname: Sutton-Tyrrell
authors.forename: K
authors.initials: K
authors.lastname: Burek
authors.forename: G S
authors.initials: GS
authors.lastname: Sopko
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D003142:Communication; D003195:Computer Communication Networks; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000628:therapy; D018153:Czech Republic; D006801:Humans; D007373:Interinstitutional Relations; D015337:Multicenter Studies as Topic / Q000379:methods; D016032:Randomized Controlled Trials as Topic / Q000379:methods; D013685:Telecommunications; D014481:United States