title: Laceration repair using a tissue adhesive in a children's emergency department.
abstract: OBJECTIVE
  To determine the effectiveness of a tissue adhesive, Histoacryl Blue (HAB), for laceration repair in children.
  
  
  METHODS
  Prospective, randomized clinical trial.
  
  
  METHODS
  A tertiary care pediatric emergency center at Egleston Children's Hospital.
  
  
  METHODS
  Children who presented for laceration repair between October 1994 and February 1995 were prospectively evaluated. Patients less than 1 or greater than 18 years of age, those with lacerations greater than 5 cm, and those with lacerations located on the eyelids, ears, nose, lips, hands, feet, joints, or perineum were excluded.
  
  
  METHODS
  Following consent and routine wound management, including subcutaneous closure when deemed necessary, patients were randomized to receive skin sutures or HAB for cutaneous closure.
  
  
  METHODS
  Length of time required for laceration repair was recorded. Parental perception of the pain experienced by their child was assessed using a visual analogue scale. Photographic documentation of scar appearance at the 2-month follow-up visit was evaluated by plastic surgeons using a visual analogue scale.
  
  
  RESULTS
  Sixty-one children were enrolled: HAB group (N = 30), suture group (N = 31). No differences occurred between groups in laceration length, depth, location, or patient demographics. Length of time required for repair was decreased (median, HAB 7 minutes vs suture 17.0 minutes) and parental assessment of their child's pain was significantly less in the HAB group. Parents were more likely to recommend HAB over suturing to other parents or guardians. Cosmetic outcome in the HAB group was assessed to be as good as, or better than, the cosmetic outcome in the suture group as evaluated by two plastic surgeons.
  
  
  CONCLUSIONS
  The use of HAB for laceration repair is an acceptable alternative to conventional suturing with a comparable cosmetic outcome. Advantages include less pain to the child, no need for suture removal, and more efficient use of physician time. Parents were also more likely to recommend HAB over suturing for laceration repair.
authors.affiliation: Department of Pediatrics, Egleston Children's Hospital, Emory University School of Medicine, Atlanta, USA.
authors.forename: T B
authors.initials: TB
authors.lastname: Bruns
authors.forename: H K
authors.initials: HK
authors.lastname: Simon
authors.forename: D J
authors.initials: DJ
authors.lastname: McLario
authors.forename: K M
authors.initials: KM
authors.lastname: Sullivan
authors.forename: R J
authors.initials: RJ
authors.lastname: Wood
authors.forename: K J
authors.initials: KJ
authors.lastname: Anand
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004630:Emergencies; D004636:Emergency Service, Hospital; D004659:Enbucrilate / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D005845:Georgia; D006776:Hospitals, Pediatric; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D013536:Suture Techniques; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014947:Wounds and Injuries / Q000628:therapy*
chemical_list: D014014:Tissue Adhesives; D004659:Enbucrilate