Double heterozygosity of chromosomal inversion in mice: a key to speciation.
Inversion can be very efficient as a reproductive barrier when the same chromosomes are involved in two different rearrangements leading to a double loop during the pachytene stage. The consequence can be a strongly reduced fertility of the double heterozygotes, leading to an irreversible dichotomy.
Rumpler
Y
Y
Institut d'Embryologie de la Faculté de Médecine de Strasbourg.
D000818:Animals; D007446:Chromosome Inversion; D005298:Fertility / Q000235:genetics; D006579:Heterozygote; D006801:Humans; D008540:Meiosis; D051379:Mice; D013045:Species Specificity