Follow-up study of adolescent girls with a history of premature pubarche.
A total of 37 girls with a history of benign premature pubarche were followed into puberty; a disproportionate number of girls experienced early menarche. Twenty-five had some degree of acne, 14 had hirsutism, and 5 had acanthosis nigricans. Body mass index (BMI) at initial presentation correlated with postpubertal BMI and was weakly correlated with postpubertal hirsutism.
Miller
D
D
Divisions of Adolescent/Young Adult Medicine and Endocrinology, Children's Hospital, Boston; and Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Emans
S J
SJ
Kohane
I
I
D000052:Acanthosis Nigricans / Q000209:etiology; D000152:Acne Vulgaris / Q000209:etiology; D000293:Adolescent; D000328:Adult; D015992:Body Mass Index; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006628:Hirsutism / Q000209:etiology; D006801:Humans; D017588:Hyperandrogenism / Q000209:etiology*; D008572:Menarche; D011237:Predictive Value of Tests; D011629:Puberty, Precocious / Q000150:complications* / Q000503:physiopathology*; D012307:Risk Factors