Liver transplantation in virus-induced chronic liver disease.
The current status of liver transplantation (OLTx) for chronic viral hepatitis is reviewed. The major issues addressed include the rate of recurrence of disease, its severity and natural history, and the potential for therapy. These issues vary markedly for each type of viral hepatitis. The development of new antiviral agents for clinical use may change the current restriction on liver transplantation for hepatitis B virus (HBV)-related liver disease such that it begins to challenge hepatitis C virus (HCV) as the principal indication for OLTx world-wide.
Colantoni
A
A
Chandler Medical Center, University of Kentucky, Lexington 40536, USA.
De Maria
N
N
Fagiuoli
S
S
Van Thiel
D H
DH
D006509:Hepatitis B / Q000517:prevention & control / Q000601:surgery* / Q000628:therapy; D006526:Hepatitis C / Q000601:surgery* / Q000628:therapy; D003699:Hepatitis D / Q000601:surgery; D006521:Hepatitis, Chronic / Q000601:surgery* / Q000821:virology; D006801:Humans; D007116:Immunization, Passive; D007136:Immunoglobulins; D016031:Liver Transplantation; D012008:Recurrence
D007136:Immunoglobulins; C045213:hepatitis B hyperimmune globulin