title: Localization of immunoreactive endothelin in the neuroendocrine cells of fish gill.
abstract: Immunohistochemical tests have demonstrated for the first time the presence of endothelins in the neuroendocrine cells of fish gill. We have sought co-localization of endothelins with serotonin and neuropeptides which are regarded as neuroendocrine markers of pulmonary diffuse neuroendocrine systems in higher vertebrates. Regarding their endocrine and paracrine activities in mammals, endothelins are considered as peptide hormones and growth factors regulating respiratory function. The roles of endothelins in the gill await investigation based on the multifunctional organization of this organ.
authors.affiliation: Department of Animal Biology and Marine Ecology, University of Messina, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Zaccone
authors.forename: A
authors.initials: A
authors.lastname: Mauceri
authors.forename: S
authors.initials: S
authors.lastname: Fasulo
authors.forename: L
authors.initials: L
authors.lastname: Ainis
authors.forename: P
authors.initials: P
authors.lastname: Lo Cascio
authors.forename: M B
authors.initials: MB
authors.lastname: Ricca
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000918:Antibody Specificity; D016232:Endothelins / Q000378:metabolism*; D005399:Fishes / Q000378:metabolism*; D019084:Fluorescent Antibody Technique, Indirect; D005880:Gills / Q000378:metabolism*; D007124:Immunoenzyme Techniques; D007150:Immunohistochemistry; D008969:Molecular Sequence Data; D009490:Neurosecretory Systems / Q000166:cytology / Q000378:metabolism*; D013045:Species Specificity
chemical_list: D016232:Endothelins