Serum cholesterol levels in patients with generalized anxiety disorder (GAD) and with GAD and comorbid major depression.
OBJECTIVE
To investigate risk for cardiovascular disease in patients with GAD, as well as the effects of comorbid major depression (MD).


METHODS
Predrug-trial serum cholesterol and triglyceride levels were assessed in 38 patients with pure GAD and compared with those of 21 patients with mixed GAD and comorbid (MD).


RESULTS
Significantly higher cholesterol and triglyceride levels were found in the GAD group.


CONCLUSIONS
Increased noradrenergic activity may be responsible for elevations in lipid levels in patients with pure GAD.
Kuczmierczyk
A R
AR
Department of Psychology, City University, London, England.
Barbee
J G
JG
Bologna
N A
NA
Townsend
M H
MH
D000328:Adult; D001008:Anxiety Disorders / Q000097:blood*; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000097:blood; D002784:Cholesterol / Q000097:blood*; D015897:Comorbidity; D003866:Depressive Disorder / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
D014280:Triglycerides; D002784:Cholesterol