title: Quinolone prophylaxis in transurethral surgery.
abstract: In transurethral surgery, there is much controversy about the benefit of antimicrobial prophylaxis. Any urinary tract infection should be treated before proceeding with a transurethral operation. There is growing evidence that antimicrobial prophylaxis is also beneficial in cases with preoperatively sterile urine. A single dose or short-term prophylaxis appears to be sufficient. As newer fluoroquinolones reach very high tissue concentrations, have a suitable antimicrobial spectrum to cover most uropathogens and can be administered orally, these new drugs represent an attractive choice for prophylaxis in transurethral surgery.
authors.affiliation: Urologic Clinic, Kantonsspital, Basel, Switzerland.
authors.forename: T C
authors.initials: TC
authors.lastname: Gasser
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001437:Bacteriuria / Q000188:drug therapy; D024841:Fluoroquinolones; D006801:Humans; D008297:Male; D011292:Premedication; D011468:Prostatectomy; D014521:Urethra
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones