title: Sexual side effects of antidepressants: a review.
abstract: Antidepressant-induced adverse sexual effects are becoming more frequently reported by patients who require pharmacotherapy. A MED-LINE search was conducted to generate articles reporting such events. We report here on the sexual side effects associated with tricyclics, monoamine oxidase inhibitors including moclobemide, selective serotonin reuptake inhibitors, bupropion, and on the newer antidepressants venlafaxine and nefazadone. We conclude that adverse sexual effects are an increasingly important side effect of antidepressant medications, and patients must be routinely asked about their occurrence.
authors.affiliation: McGill University, Canada.
authors.forename: H C
authors.initials: HC
authors.lastname: Margolese
authors.forename: P
authors.initials: P
authors.lastname: Assalian
mesh_terms: D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects / Q000494:pharmacology*; D001549:Benzamides / Q000009:adverse effects / Q000494:pharmacology*; D016642:Bupropion / Q000009:adverse effects / Q000494:pharmacology*; D005260:Female; D006801:Humans; D007989:Libido / Q000187:drug effects; D008297:Male; D020912:Moclobemide; D008996:Monoamine Oxidase Inhibitors / Q000009:adverse effects / Q000494:pharmacology*; D010410:Penile Erection / Q000187:drug effects; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects / Q000494:pharmacology*; D012725:Sexual Behavior / Q000187:drug effects*; D020018:Sexual Dysfunctions, Psychological / Q000139:chemically induced
chemical_list: D000929:Antidepressive Agents, Tricyclic; D001549:Benzamides; D016642:Bupropion; D020912:Moclobemide; D008996:Monoamine Oxidase Inhibitors; D017367:Selective Serotonin Reuptake Inhibitors