title: Influence of the mechanism of regurgitation on the quantification of mitral regurgitation by the proximal flow convergence method and the jet area method.
abstract: In 84 patients mitral regurgitation was quantified by angiography. The mechanism of regurgitation was determined by echocardiography (organic, n = 54, functional, n = 30). The radii of the proximal isovelocity surface areas in the flow convergence region for 28 and 41 cm.s-1 blood flow velocity and the area and length of the regurgitant jet were measured using colour flow Doppler imaging. The radii of the proximal isovelocity surface areas correlated more closely with the angiographic grade than the jet parameters irrespective of the mechanism of regurgitation. In more than 90% of the patients, grades I-II mitral regurgitation were correctly differentiated from grades III-IV by means of the radii of the proximal isovelocity surface areas. Using the jet parameters, the differentiation was correct in 50-90% of the patients depending on the mechanism of regurgitation. The jet area method particularly failed to identify grades III-IV organic mitral regurgitation due to a high prevalence of eccentric jets in these patients. It is concluded that the proximal flow convergence method was suitable for the quantification of mitral regurgitation irrespective of the mechanism of mitral regurgitation. On the other hand, the value of the jet area method depended largely on the regurgitation mechanism.
authors.affiliation: Department of Internal Medicine, University of Ulm, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Grossmann
authors.forename: M
authors.initials: M
authors.lastname: Giesler
authors.forename: A
authors.initials: A
authors.lastname: Schmidt
authors.forename: M
authors.initials: M
authors.lastname: Kochs
authors.forename: S
authors.initials: S
authors.lastname: Wieshammer
authors.forename: M
authors.initials: M
authors.lastname: Höher
authors.forename: C
authors.initials: C
authors.lastname: Felder
authors.forename: V
authors.initials: V
authors.lastname: Hombach
mesh_terms: D000328:Adult; D000368:Aged; D000790:Angiocardiography; D001783:Blood Flow Velocity; D006328:Cardiac Catheterization; D018618:Echocardiography, Doppler, Color / Q000379:methods*; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000503:physiopathology*; D015588:Observer Variation; D011897:Random Allocation