title: Preoperative endovascular embolization of craniospinal hemangioblastomas.
abstract: OBJECTIVE
  To determine whether hemangioblastomas, highly vascular tumors requiring surgery that is potentially complicated by excessive bleeding, can be embolized safely by using interventional techniques that furnish a more avascular surgical field.
  
  
  METHODS
  Nine hemangioblastomas involving either the cerebellum or the spinal cord were embolized preoperatively. In each case the feeding artery was selectively catheterized with a microcatheter and the hypervascular tumor nidus was devascularized with polyvinyl alcohol particles.
  
  
  RESULTS
  Two patients who had undergone recent attempts as surgical resection at another institution had repeat surgery after endovascular embolization rendered the tumor nidus avascular. At surgery, the tumor was completely removed in one case and markedly debulked in the other. In all nine cases, blood loss after embolization was reported to be less than expected by experienced surgeons. In addition, manipulation and removal of the tumor was reported to be subjectively easier in these embolized tumors. The embolization procedure caused no permanent complications; however, one patient with a posterior fossa hemangioblastoma and hydrocephalus worsened clinically within 12 hours of embolization. This event was thought to be caused by obstructive hydrocephalus resulting from tumor swelling. Emergency craniotomy, ventricular decompression, and surgical resection of the tumor produced complete resolution of the signs and symptoms.
  
  
  CONCLUSIONS
  Our results indicate that preoperative embolization of hemangioblastomas is a safe procedure that is useful in aiding surgical resection of these highly vascular tumors.
authors.affiliation: Department of Radiology, University of Washington, Seattle 98195, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Eskridge
authors.forename: W
authors.initials: W
authors.lastname: McAuliffe
authors.forename: B
authors.initials: B
authors.lastname: Harris
authors.forename: D K
authors.initials: DK
authors.lastname: Kim
authors.forename: J
authors.initials: J
authors.lastname: Scott
authors.forename: H R
authors.initials: HR
authors.lastname: Winn
mesh_terms: D000293:Adolescent; D000328:Adult; D000792:Angiography; D004621:Embolization, Therapeutic; D005260:Female; D018325:Hemangioblastoma / Q000098:blood supply / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D008297:Male; D008863:Microspheres; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011300:Preoperative Care; D012888:Skull Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging / Q000628:therapy*; D013125:Spinal Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging / Q000628:therapy*