title: Practical experience and issues in designing and performing population pharmacokinetic/pharmacodynamic studies.
abstract: An expert meeting to discuss issues relating to the design of population pharmacokinetic/pharmacodynamic (PK/PD) studies was held in Brussels in March 1995, under the auspices of the European Co-operation in Science and Technology (COST), Medicine (B1) programme. The purpose of the meeting was to discuss the experts' experience in designing and performing population PK/PD studies. The topics discussed were current practice, logistical issues, ensuring the accuracy of data, covariate assessment, communication, and protocol design.
authors.affiliation: Department of Pharmacy, University of Manchester, UK.
authors.forename: L
authors.initials: L
authors.lastname: Aarons
authors.forename: L P
authors.initials: LP
authors.lastname: Balant
authors.forename: F
authors.initials: F
authors.lastname: Mentre
authors.forename: P L
authors.initials: PL
authors.lastname: Morselli
authors.forename: M
authors.initials: M
authors.lastname: Rowland
authors.forename: J L
authors.initials: JL
authors.lastname: Steimer
authors.forename: S
authors.initials: S
authors.lastname: Vozeh
mesh_terms: D001530:Belgium; D002986:Clinical Trials as Topic; D010599:Pharmacokinetics; D012107:Research Design