title: Localized lipoatrophia with persistent circulating autoantibodies and partial immunoglobulin A deficiency in a child.
abstract: A 7-year-old Caucasian girl developed lipoatrophic areas on the abdomen and left thigh. Laboratory tests showed a partial IgA deficiency, circulating autoantibodies (ANAs, double- and single-stranded anti-DNAs, rheumatoid factor). The clinical aspect resembles lipodystrophia centrifugalis abdominalis infantilis, but autoimmune abnormalities suggest connective tissue panniculitis which underlines the overlap between the different forms of localized lipoatrophias.
authors.affiliation: Department of Dermatology, Venereology and Allergology, CHU Purpan, Toulouse, France.
authors.forename: C
authors.initials: C
authors.lastname: Trémeau-Martinage
authors.forename: P
authors.initials: P
authors.lastname: Bayle-Lebey
authors.forename: E
authors.initials: E
authors.lastname: Grouteau
authors.forename: J
authors.initials: J
authors.lastname: Bazex
mesh_terms: D001323:Autoantibodies / Q000097:blood*; D002648:Child; D005260:Female; D006801:Humans; D017098:IgA Deficiency / Q000150:complications* / Q000276:immunology / Q000473:pathology; D008060:Lipodystrophy / Q000150:complications* / Q000276:immunology / Q000473:pathology
chemical_list: D001323:Autoantibodies