title: Blood transfusions in laryngeal cancer: effect on prognosis.
abstract: METHODS
  To evaluate the influence of homologous perioperative transfusion on oncologic control and survival in patients with larynx and hypopharynx carcinomas, we conducted a retrospective study of 269 patients with larynx and hypopharynx carcinoma treated by major surgical procedures. A total of 20 variables were analyzed for each patient.
  
  
  RESULTS
  Perioperative transfusion was required in 86 (32%) patients, with packed red blood cells being used in all cases. Recurrence at a local, regional, or distant level was 31% for nontransfused and 35% for transfused patients. The 5-year adjusted survival was 68% for patients without transfusion and 63% for patients with transfusion. Neither the univariate nor the multivariate analysis showed that perioperative transfusion or the number of units of packed red blood cells used had any prognostic capacity.
  
  
  CONCLUSIONS
  Homologous perioperative transfusion did not imply a significant risk regarding global control or survival in our larynx or hypopharynx cancer patients.
authors.affiliation: Department of Otorhinolaryngology, Hospital de la Sta., Barcelona, Spain.
authors.forename: X
authors.initials: X
authors.lastname: Leon
authors.forename: M
authors.initials: M
authors.lastname: Quer
authors.forename: M
authors.initials: M
authors.lastname: Luz Maestre
authors.forename: J
authors.initials: J
authors.lastname: Burgues
authors.forename: E
authors.initials: E
authors.lastname: Muniz
authors.forename: P
authors.initials: P
authors.lastname: Madoz
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D001803:Blood Transfusion; D016009:Chi-Square Distribution; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000401:mortality* / Q000601:surgery / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010610:Pharyngeal Neoplasms / Q000175:diagnosis / Q000401:mortality* / Q000601:surgery / Q000628:therapy*; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate