Effects of long-term high manganese intake on magnesium metabolism in rats.
The effects of long-term high manganese intake on the magnesium metabolism in rats were studied. One group of rats was fed a normal diet and the treated group received a normal diet and distilled water containing 2 g/litre manganese (as MnCl2). Metabolic studies showed that after 11 weeks of treatment, manganese supplementation modified magnesium metabolism by increasing urinary magnesium excretion and decreasing magnesium balance.
Gaillard
E
E
Laboratoire Physiologie, Faculté de Médecine, Besançon, France.
Laurant
P
P
Robin
S
S
Berthelot
A
A
D000818:Animals; D001835:Body Weight / Q000187:drug effects; D004435:Eating / Q000187:drug effects; D005243:Feces / Q000737:chemistry; D005527:Food, Fortified; D008274:Magnesium / Q000378:metabolism* / Q000652:urine; D008297:Male; D008345:Manganese / Q000097:blood / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013997:Time Factors
D008345:Manganese; D008274:Magnesium