Diabetes mellitus and morbidity and mortality risks after coronary artery bypass surgery.
Of 1025 patients (912 men, 113 women) who underwent coronary artery bypass grafting and were followed up for a mean of 7.4 years, 45 (4.4%) had diabetes mellitus. Norwegian population is 1.8-2%). Early mortality was not significantly greater among diabetics than in non-diabetics (2.2 vs. 3.1%, odds ratio--OR-0.44, confidence interval--CI- 0.05-3.56). Diabetic patients had no increased risk of perioperative myocardial infarction (OR = 0.87, CI 0.36-2.10) or of low-output syndrome necessitating intraortic balloon pumping (OR = 0.42, CI 0.55-3.05), and no excess incidence of late non-fatal myocardial infarction (relative risk = 0.69, CI 0.10-1.28) or late chronic heart failure (OR = 2.50, CI 0.5-11.0). Long-term mortality was increased in the diabetic patients (relative risk 1.87, CI 1.60-2.14). Thus diabetes did not entail heightened risk of early mortality, perioperative myocardial infarction or low-output syndrome. Nor was there excess risk of recurrent angina pectoris, late non-fatal myocardial infarction or chronic heart failure among the diabetic patients, but the late mortality risk was increased.
Risum
O
O
Surgical Department, Rikshospitalet, University of Oslo, Norway.
Abdelnoor
M
M
Svennevig
J L
JL
Levorstad
K
K
Gullestad
L
L
Bjørnerheim
R
R
Simonsen
S
S
Nitter-Hauge
S
S
D000787:Angina Pectoris / Q000453:epidemiology; D002303:Cardiac Output, Low / Q000453:epidemiology; D016001:Confidence Intervals; D015986:Confounding Factors, Epidemiologic; D001026:Coronary Artery Bypass / Q000009:adverse effects* / Q000401:mortality; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000401:mortality; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007423:Intra-Aortic Balloon Pumping / Q000706:statistics & numerical data; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology; D009664:Norway / Q000453:epidemiology; D016017:Odds Ratio; D011183:Postoperative Complications / Q000453:epidemiology; D015995:Prevalence; D012008:Recurrence; D012307:Risk Factors; D015996:Survival Rate