title: A transparent model of the human scala tympani cavity.
abstract: A dimensionally accurate clear model of the human scala tympani has been produced to evaluate the insertion and position of clinically applied intracochlear electrodes for electrical stimulation. Replicates of the human scala tympani were made from low melting point metal alloy (LMA) and from polymethylmeth-acrylate (PMMA) resin. The LMA metal casts were embedded in blocks of epoxy and in clear silicone rubber. After removal of the metal alloy, a cavity was produced that accurately models the human scala tympani. Investment casting molds were made from the PMMA scala tympani casts to enable production of multiple LMA casts from which identical models were fabricated. Total dimensional distortion of the LMA casting process was less than 1% in length and 2% in diameter. The models have been successfully integrated into the design process for the iterative development of advanced intracochlear electrode arrays at UCSF. These fabrication techniques are applicable to a wide range of biomedical design problems that require modelling of visually obscured cavities.
authors.affiliation: Department of Otolaryngology, University of California, San Francisco 94143-0526, USA.
authors.forename: S J
authors.initials: SJ
authors.lastname: Rebscher
authors.forename: N
authors.initials: N
authors.lastname: Talbot
authors.forename: W
authors.initials: W
authors.lastname: Bruszewski
authors.forename: M
authors.initials: M
authors.lastname: Heilmann
authors.forename: J
authors.initials: J
authors.lastname: Brasell
authors.forename: M M
authors.initials: MM
authors.lastname: Merzenich
mesh_terms: D000497:Alloys; D003054:Cochlear Implants; D016319:Corrosion Casting; D004558:Electric Stimulation / Q000295:instrumentation; D006801:Humans; D008670:Metals; D008768:Methylmethacrylates; D008953:Models, Anatomic; D012533:Scala Tympani / Q000033:anatomy & histology*
chemical_list: D000497:Alloys; D008670:Metals; D008768:Methylmethacrylates