Quinolone prophylaxis in transurethral surgery.
In transurethral surgery, there is much controversy about the benefit of antimicrobial prophylaxis. Any urinary tract infection should be treated before proceeding with a transurethral operation. There is growing evidence that antimicrobial prophylaxis is also beneficial in cases with preoperatively sterile urine. A single dose or short-term prophylaxis appears to be sufficient. As newer fluoroquinolones reach very high tissue concentrations, have a suitable antimicrobial spectrum to cover most uropathogens and can be administered orally, these new drugs represent an attractive choice for prophylaxis in transurethral surgery.
Gasser
T C
TC
Urologic Clinic, Kantonsspital, Basel, Switzerland.
D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001437:Bacteriuria / Q000188:drug therapy; D024841:Fluoroquinolones; D006801:Humans; D008297:Male; D011292:Premedication; D011468:Prostatectomy; D014521:Urethra
D000890:Anti-Infective Agents; D024841:Fluoroquinolones