title: The taste of intravenous thiopentone.
abstract: Patients sometimes notice an onion or garlic taste before losing consciousness with thiopentone. An assessment of 113 patients revealed that 42% of patients noticed this taste. The effect was observed less in older patients. There was no statistically significant difference in the incidence between men and women. Premedicated patients had a lower incidence, but this was explained by the greater proportion of older patients receiving a premedication. If the taste effect of thiopentone is genetically determined then it is a different gene to thiocarbamate which has about 75% tasters.
authors.affiliation: Royal Adelaide Hospital, South Australia.
authors.forename: N B
authors.initials: NB
authors.lastname: Nor
authors.forename: M A
authors.initials: MA
authors.lastname: Fox
authors.forename: I R
authors.initials: IR
authors.lastname: Metcalfe
authors.forename: W J
authors.initials: WJ
authors.lastname: Russell
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology; D000490:Allium; D018686:Anesthetics, Intravenous / Q000008:administration & dosage* / Q000494:pharmacology*; D002648:Child; D005260:Female; D005737:Garlic; D006801:Humans; D015994:Incidence; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D010946:Plants, Medicinal; D011292:Premedication; D013649:Taste / Q000187:drug effects* / Q000502:physiology; D013874:Thiopental / Q000008:administration & dosage* / Q000494:pharmacology*
chemical_list: D018686:Anesthetics, Intravenous; D013874:Thiopental