title: Electrophysiologic Study versus Electrocardiographic Monitoring (ESVEM): a critical appraisal.
abstract: This paper reviews the Electrophysiologic Study versus Holter Monitoring (ESVEM) trial, addressing several areas of concern including potential enrollment bias, an inadequate electrophysiologic testing protocol during drug therapy, and an unexpectedly high recurrence rate in patients deemed to be controlled by either method. The paper concludes that there are insufficient data to warrant extrapolation of the ESVEM results to survivors of cardiac arrest.
authors.affiliation: St. Vincent Hospital, Indianapolis, Indiana, USA.
authors.forename: E N
authors.initials: EN
authors.lastname: Prystowsky
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy* / Q000503:physiopathology; D016757:Death, Sudden, Cardiac / Q000517:prevention & control; D015716:Electrocardiography, Ambulatory; D004594:Electrophysiology; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D017180:Tachycardia, Ventricular / Q000188:drug therapy / Q000503:physiopathology; D014481:United States; D014693:Ventricular Fibrillation / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D000889:Anti-Arrhythmia Agents