Effect of ketoconazole-medicated shampoos on squamometry and Malassezia ovalis load in pityriasis capitis.
Pityriasis capitis is improved by the use of antifungal shampoos. A double-blind randomized, placebo-controlled study was conducted to compare the efficacy of ketoconazole 0.5 percent and 1 percent formulation shampoos. Evaluations were made in seventy-eight volunteers before and after a two-week duration of daily shampooing. Grading the Malassezia ovalis load in dandruff and values of squamometry were used as noninvasive methods to evaluate efficacy.
Arrese
J E
JE
Department of Dermatopathology, University of Liège, Belgium.
Piérard-Franchimont
C
C
De Doncker
P
P
Heremans
A
A
Cauwenbergh
G
G
Piérard
G E
GE
D000293:Adolescent; D000328:Adult; D004311:Double-Blind Method; D005260:Female; D006203:Hair Preparations; D006801:Humans; D007654:Ketoconazole / Q000008:administration & dosage*; D008290:Malassezia / Q000302:isolation & purification*; D008297:Male; D008875:Middle Aged; D010915:Pityriasis / Q000188:drug therapy* / Q000382:microbiology; D012536:Scalp Dermatoses / Q000188:drug therapy*
D006203:Hair Preparations; D007654:Ketoconazole