title: Obstetric outcome of pregestational diabetic pregnancies.
abstract: This retrospective study examined the obstetric and neonatal outcome in 23 pregestational diabetic pregnancies. The incidence of congenital malformations and mortality in infants of diabetic mothers was increased compared to the control population. Late booking for antenatal care and poor glycaemia control are probably the reasons for this high incidence. There was also a significantly higher preterm delivery and Caesarean section rate in the pregnancies complicated by pregestational diabetes. The neonatal morbidity was also higher than the controls in terms of jaundice, hypoglycaemia, respiratory distress syndrome and admissions to neonatal intensive care unit. Only with preconception counselling and tight glycaemia control in the periconception period and throughout pregnancy can we expect a drop in the complication rates in pregestational diabetic pregnancies.
authors.affiliation: Department of Obstetrics & Gynaecology, National University Hospital, Singapore.
authors.forename: Y T
authors.initials: YT
authors.lastname: Chia
authors.forename: S
authors.initials: S
authors.lastname: Chua
authors.forename: A C
authors.initials: AC
authors.lastname: Thai
authors.forename: S C
authors.initials: SC
authors.lastname: Yeoh
authors.forename: L P
authors.initials: LP
authors.lastname: Kek
authors.forename: N
authors.initials: N
authors.lastname: Selamat
authors.forename: S S
authors.initials: SS
authors.lastname: Ratnam
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000503:physiopathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology*; D011256:Pregnancy Outcome; D011254:Pregnancy in Diabetics / Q000150:complications* / Q000503:physiopathology / Q000628:therapy; D018566:Pregnancy, High-Risk; D011295:Prenatal Care / Q000379:methods; D011379:Prognosis; D012189:Retrospective Studies
chemical_list: D001786:Blood Glucose