title: Therapeutic proteins and enzymes from genetically engineered yeasts.
abstract: Human proteins, including enzymes, manufactured with recombinant-DNA yeasts can be used to treat a variety of medical conditions; some redesign of molecular structure (and production techniques) should increase their specificity, efficacy and immunotolerance. Prevention and treatment of diseases due to reactive oxygen species (ROS) and reactive nitrogen species (RNS) may become possible. Therapeutic vaccines for some diseases may be produced by design-specification for particular desirable protein features, on an individual patient basis.
authors.affiliation: University of Surrey, Guildford.
authors.forename: A
authors.initials: A
authors.lastname: Wiseman
mesh_terms: D004274:DNA, Recombinant / Q000235:genetics; D004358:Drug Therapy; D057487:Enzyme Therapy; D004798:Enzymes / Q000235:genetics*; D005818:Genetic Engineering; D006801:Humans; D007108:Immune Tolerance; D015394:Molecular Structure; D009584:Nitrogen / Q000627:therapeutic use; D017382:Reactive Oxygen Species; D011994:Recombinant Proteins / Q000235:genetics* / Q000627:therapeutic use; D013045:Species Specificity; D014614:Vaccines, Synthetic; D015003:Yeasts / Q000235:genetics*
chemical_list: D004274:DNA, Recombinant; D004798:Enzymes; D017382:Reactive Oxygen Species; D011994:Recombinant Proteins; D014614:Vaccines, Synthetic; D009584:Nitrogen