title: Double heterozygosity of chromosomal inversion in mice: a key to speciation.
abstract: Inversion can be very efficient as a reproductive barrier when the same chromosomes are involved in two different rearrangements leading to a double loop during the pachytene stage. The consequence can be a strongly reduced fertility of the double heterozygotes, leading to an irreversible dichotomy.
authors.affiliation: Institut d'Embryologie de la Faculté de Médecine de Strasbourg.
authors.forename: Y
authors.initials: Y
authors.lastname: Rumpler
mesh_terms: D000818:Animals; D007446:Chromosome Inversion; D005298:Fertility / Q000235:genetics; D006579:Heterozygote; D006801:Humans; D008540:Meiosis; D051379:Mice; D013045:Species Specificity