title: Laboratory diagnosis of insulinoma in the dog: a retrospective study and a new diagnostic procedure.
abstract: Simultaneous insulin and glucose measurements from a single sample are often insufficient for the laboratory diagnosis of insulinoma in the hypoglycaemic dog. Although the simple insulin (microU/litre): glucose (mmol/litre) ratio is best, when the selected threshold is set at 13.5, it is not always efficient to confirm or refute insulinoma. The fasting test consists of collecting four samples on a given day (no accurate time period is set between any two samples) from a fasting dog for simultaneous insulin and glucose measurements to detect at least one abnormal insulinaemia peak.
authors.affiliation: Department of Biology and Pharmacology, Laboratoire des Dosages Hormonaux-Laboratoire National de Référence, Ecole Vétérinaire de Nantes, France.
authors.forename: B
authors.initials: B
authors.lastname: Siliart
authors.forename: F
authors.initials: F
authors.lastname: Stambouli
mesh_terms: D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D003955:Diagnostic Tests, Routine / Q000662:veterinary*; D004283:Dog Diseases / Q000097:blood / Q000175:diagnosis*; D004285:Dogs / Q000097:blood*; D007003:Hypoglycemia / Q000097:blood / Q000662:veterinary; D007328:Insulin / Q000097:blood; D007340:Insulinoma / Q000097:blood / Q000175:diagnosis / Q000662:veterinary*; D010190:Pancreatic Neoplasms / Q000097:blood / Q000175:diagnosis / Q000662:veterinary*; D012189:Retrospective Studies; D013997:Time Factors
chemical_list: D001786:Blood Glucose; D007328:Insulin