title: Drug-resistant mycobacterium tuberculosis; some data from Sweden, Estonia and Ethiopia.
abstract: Drug-resistant tuberculosis is a threat not only to the estimated 50 million people in the world carrying resistant strains, but also to the success of national TB control programmes. In Sweden, multidrug-resistant (MDR) tuberculosis comprises around 1% of the isolated strains. Isoniazid resistance is found in 7% of strains and resistance to other drugs in < 3%. Of patients with resistant TB 70% are born outside Scandinavia. Preliminary data from Estonia show that close to 20% of the strains are resistant to each of the drugs isoniazid, rifampicin and streptomycin. MDR is seen in around 16%. In a study in Ethiopia isoniazid resistance was found in 46% and MDR in 11% among treatment failures and relapse cases.
authors.affiliation: Microbiology and Tumorbiology Center, Karolinska Institute and Swedish Institute for Infectious Disease Control, Stockholm, Sweden.
authors.forename: S E
authors.initials: SE
authors.lastname: Hoffner
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D004957:Estonia / Q000453:epidemiology; D005002:Ethiopia / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D013548:Sweden / Q000453:epidemiology; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy / Q000453:epidemiology*
chemical_list: D000995:Antitubercular Agents