title: Acanthamoeba endophthalmitis in acquired immunodeficiency syndrome.
abstract: OBJECTIVE
  To report the findings of Acanthamoeba endophthalmitis in a patient with acquired immunodeficiency syndrome (AIDS).
  
  
  METHODS
  A 35-year-old man with AIDS and Acanthamoeba infection of the skin and lungs was treated for a granulomatous uveitis in the left eye.
  
  
  RESULTS
  The left eye developed mutton-fat keratic precipitates, iris granulomas, cataract, hypotony, and choroidal infiltrates. Aqueous and vitreous specimens were positive for Acanthamoeba cysts. Topical and systemic antiamebic medications decreased the inflammation but failed to control the infection.
  
  
  CONCLUSIONS
  Acanthamoeba infection should be considered in the differential diagnosis of uveitis in patients with AIDS.
authors.affiliation: Department of Ophthalmology, Allegheny University of the Health Sciences, Philadelphia, PA 19102, 1192, USA. Heffler@Allegheny.edu
authors.forename: K F
authors.initials: KF
authors.lastname: Heffler
authors.forename: T J
authors.initials: TJ
authors.lastname: Eckhardt
authors.forename: A C
authors.initials: AC
authors.lastname: Reboli
authors.forename: D
authors.initials: D
authors.lastname: Stieritz
mesh_terms: D000048:Acanthamoeba / Q000302:isolation & purification; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000562:Amebiasis / Q000150:complications* / Q000188:drug therapy; D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001082:Aqueous Humor / Q000469:parasitology; D003937:Diagnosis, Differential; D009877:Endophthalmitis / Q000150:complications* / Q000188:drug therapy / Q000469:parasitology; D015822:Eye Infections, Parasitic / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008174:Lung Diseases, Parasitic / Q000150:complications / Q000188:drug therapy; D008297:Male; D012871:Skin Diseases / Q000150:complications / Q000188:drug therapy; D014822:Vitreous Body / Q000469:parasitology
chemical_list: D000981:Antiprotozoal Agents