Severe hemolysis caused by graft-derived anti-B production after lung transplantation.
Anti-B antibody causing sever hemolytic anemia and renal failure was found in the serum of a blood group B patient who had received a bilateral lung transplant from a blood group O donor. Although the donor origin of the antibody was not confirmed, it is likely that the anti-B antibody was produced by donor passenger B lymphocytes.
Taaning
E
E
Department of Clinical Immunology, State University Hospital, Rigshospitalet, Copenhagen, Denmark.
Morling
N
N
Mortensen
S A
SA
Pettersson
G
G
Simonsen
A C
AC
D000017:ABO Blood-Group System / Q000276:immunology*; D000917:Antibody Formation; D006084:Graft Rejection / Q000276:immunology* / Q000517:prevention & control; D006086:Graft vs Host Disease / Q000188:drug therapy / Q000276:immunology*; D006461:Hemolysis / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016040:Lung Transplantation / Q000276:immunology*; D008297:Male; D008875:Middle Aged
D000017:ABO Blood-Group System; D007074:Immunoglobulin G; D007166:Immunosuppressive Agents