title: [Actinomycosis and non-Hodgkin's malignant lymphoma: fortuitous association?].
abstract: Two cases of actinomycosis associated with non Hodgkin's lymphoma (NHL) are reported. In one case, low grade NHL was diagnosed many years after actinomycosis because of the persistence of abdominal lymphadenopathy in spite of antibiotic therapy. In the second case, hepatic metastasis were initially suspected until actinomycosis diagnosis was made by percutaneous liver biopsy under scanography. High grade NHL was diagnosed by laparotomy and liver biopsy performed 6 weeks after the onset of antibiotic therapy as no improvement in hepatic lesions was obtained. These two case reports outline the difficulties encountered in the diagnosis of actinomycosis and the indication of a repeat biopsy when actinomycosis does not respond to antimicrobial therapy because of the possibility of concomitant malignancy.
authors.affiliation: Service de médecine A, CHU Brabois, Vandoeuvre-lès-Nancy, France.
authors.forename: A P
authors.initials: AP
authors.lastname: Guerci
authors.forename: M
authors.initials: M
authors.lastname: Merle-Melet
authors.forename: F
authors.initials: F
authors.lastname: Mory
authors.forename: A
authors.initials: A
authors.lastname: Blum
authors.forename: J
authors.initials: J
authors.lastname: Floquet
authors.forename: M
authors.initials: M
authors.lastname: Deneuville
authors.forename: P
authors.initials: P
authors.lastname: Boissel
authors.forename: P
authors.initials: P
authors.lastname: Lederlin
mesh_terms: D000196:Actinomycosis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D000328:Adult; D015984:Causality; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008875:Middle Aged