title: Colectomy for severe slow-transit constipation in strictly selected patients.
abstract: BACKGROUND
  Colectomy for severe constipation has in up to 25% of patients given unsatisfactory results. Failure to cure constipation is in most patients due to rectal dysfunction. The aim of the present study was to evaluate the effect of colectomy in a group of patients who fulfil all the criteria which, with our present knowledge, should predict a favourable result.
  
  
  METHODS
  Twelve patients with long-standing severe constipation incurable by dietary regulation and medical treatment with demonstrable slow-transit constipation and normal rectal function entered the study.
  
  
  RESULTS
  Ten patients were relieved of their constipation. Two patients continued to be constipated after subtotal colectomy. One had a very highly compliant rectum (preoperatively) with a maximal tolerable volume of 700 ml but normal emptying at defecography and normal emptying of viscous fluid. The patient was subsequently treated with proctectomy and ileo-pouch-anal anastomosis with satisfactory result. One patient with opioid abuse due to abdominal pain was improved by the operation but was still constipated. The opioid abuse continued, however, after the operation owing to continuing abdominal pain. A further three patients complained of abdominal pain, and two developed diarrhoea, one of whom became incontinent.
  
  
  CONCLUSIONS
  Subtotal or segmental colectomy should be considered in a small number of patients with severe constipation provided strict criteria are fulfilled. Excessively high rectal volume tolerability may in spite of normal emptying capacity indicate the risk of development of rectal inertia postoperatively and may be a contraindication for surgery.
authors.affiliation: Dept. of Surgery D, Herlev Hospital, University of of Copenhagen, Denmark.
authors.forename: J
authors.initials: J
authors.lastname: Christiansen
authors.forename: O O
authors.initials: OO
authors.lastname: Rasmussen
mesh_terms: D000328:Adult; D000368:Aged; D002908:Chronic Disease; D003082:Colectomy; D003248:Constipation / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018579:Patient Selection