Examination of the working memory components in normal aging and in dementia of the Alzheimer type.
The verbal and attentional components of working memory were examined in patients with Alzheimer's disease, normal elderlies, and young controls. Patients with Alzheimer's disease, showed a reduced span but were sensitive to word length. This is indicative of a functional rehearsal procedure. However, the effect of phonological similarity on immediate recall was smaller in patients with Alzheimer's disease and these patients showed a depressed performance in tasks of phonological analysis. There was also a significant decrement in a task that assessed the attentional component of working memory. Examination of individual patterns of performance showed that the phonological deficiency was severe in a subgroup of patients while the attentional deficit was more general.
Belleville
S
S
Centre de Recherche du Centre Hospitalier Côte-des-Neiges, Montréal, Québec, Canada.
Peretz
I
I
Malenfant
D
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000523:psychology*; D000544:Alzheimer Disease / Q000523:psychology*; D001307:Auditory Perception / Q000502:physiology; D003071:Cognition / Q000502:physiology; D004192:Discrimination, Psychological / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008570:Memory, Short-Term / Q000502:physiology*; D008875:Middle Aged; D009483:Neuropsychological Tests; D014706:Verbal Learning / Q000502:physiology