title: Population data on the loci LDLR, GYPA, HBGG, D7S8, and GC in three southwest European populations.
abstract: Three Southwest European populations: Galicia (NW Spain), a mixed Spanish population from the rest of Spain (outside Galicia), and a population sample from the Coimbra area (Centre of Portugal) have been studied for the Low Density Lipoprotein Receptor (LDLR), Glycophorin A (GYPA), Hemoglobin G Gammaglobin (HBGG), D7S8 and Group Specific Component (GC). The allele and genotype frequencies found have been compared with other previously published data. All loci meet Hardy-Weinberg expectations in the three sampled populations. There was no evidence of association in any of the three population samples, between the five loci studied. No significant differences were found with Caucasian populations, nevertheless, significant differences were observed between our three population studies and the US SW Hispanic and African populations. The AmpliType PM DNA test greatly facilitates DNA testing in forensic laboratories, providing quick results and a good discrimination power from a single test.
authors.affiliation: Institute of Legal Medicine, University of Santiago de Compostela, Spain.
authors.forename: M S
authors.initials: MS
authors.lastname: Rodriguez-Calvo
authors.forename: S
authors.initials: S
authors.lastname: Bellas
authors.forename: L
authors.initials: L
authors.lastname: Souto
authors.forename: C
authors.initials: C
authors.lastname: Vide
authors.forename: E
authors.initials: E
authors.lastname: Valverde
authors.forename: A
authors.initials: A
authors.lastname: Carracedo
mesh_terms: D004247:DNA / Q000032:analysis; D005554:Forensic Medicine; D005787:Gene Frequency; D005819:Genetic Markers / Q000235:genetics; D006021:Glycophorins / Q000235:genetics*; D006683:HLA-DQ Antigens; D006455:Hemoglobins, Abnormal / Q000235:genetics*; D006801:Humans; D016133:Polymerase Chain Reaction; D011174:Portugal / Q000208:ethnology; D011973:Receptors, LDL / Q000235:genetics*; D013030:Spain / Q000208:ethnology; D014809:Vitamin D-Binding Protein / Q000235:genetics*
chemical_list: D005819:Genetic Markers; D006021:Glycophorins; D006683:HLA-DQ Antigens; C051568:HLA-DQ1 antigen; D006455:Hemoglobins, Abnormal; D011973:Receptors, LDL; D014809:Vitamin D-Binding Protein; D004247:DNA