The effect of reduced extrinsic sucrose intake on plasma triglyceride levels.
OBJECTIVE
To examine the effect on plasma triglycerides of removing most of the extrinsic sugar from the diet of free living hypertriglyceridaemic individuals while controlling weight loss.


METHODS
Free living subjects were randomly assigned to intervention and control groups. The intervention group undertook to consume a "sugar free' diet for six months after a three month baseline period. The control group maintained their usual diets for the nine month period. The results from the two groups were compared using repeated measures ANOVA.


METHODS
Thirty two hypertriglyceridaemic individuals, selected from members of the public in Dunedin, New Zealand.


RESULTS
Subjects in the intervention group were able to achieve a mean reduction in sucrose intake of > 70%, largely extrinsic sucrose, resulting in a group mean reduction in plasma triglyceride levels of > 20% and a mean weight loss over the six month period of about 2%. Repeated measures ANOVA on the mean triglyceride figures after the individual figures had been adjusted for this small weight loss, showed that there was a significant fall in triglyceride levels over the study period compared with the baseline.


CONCLUSIONS
Hypertriglyceridaemia can be reduced in some individuals by the reduction of extrinsic sucrose in the diet. When allowance is made for weight loss the reduction is still significant.
Smith
J B
JB
Department of Human Nutrition, University of Otago, Dunedin, New Zealand.
Niven
B E
BE
Mann
J I
JI
D000328:Adult; D000704:Analysis of Variance; D001835:Body Weight; D002784:Cholesterol / Q000097:blood / Q000378:metabolism; D008076:Cholesterol, HDL / Q000097:blood / Q000378:metabolism; D004032:Diet; D019422:Dietary Sucrose / Q000008:administration & dosage* / Q000009:adverse effects / Q000378:metabolism; D006801:Humans; D015228:Hypertriglyceridemia / Q000097:blood / Q000503:physiopathology*; D008875:Middle Aged; D013549:Sweetening Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000378:metabolism; D013997:Time Factors; D014280:Triglycerides / Q000097:blood*
D008076:Cholesterol, HDL; D019422:Dietary Sucrose; D013549:Sweetening Agents; D014280:Triglycerides; D002784:Cholesterol