title: The role of macronutrient selection in determining patterns of food intake in obese and non-obese women.
abstract: OBJECTIVE
  Examination of the role of macronutrient selection in determining patterns of food intake in obese and non-obese women.
  
  
  METHODS
  Inventory: food intake diaries of two weekdays and one weekend day; EXPERIMENT randomized.
  
  
  METHODS
  Inventory: in daily life.
  
  
  METHODS
  department of Human Biology, University of Limburg.
  
  
  METHODS
  68 subjects: 34 obese and 34 non-obese, age 20-50 years, selected based on accurate completion of food intake diaries (< 10% underreporting); a sub-sample of 32 (16 obese and 16 non-obese) was assigned to the experiment.
  
  
  METHODS
  An ample choice of food items consisting of mainly one macronutrient each were offered 4 and 6 times per day, with different macronutrient compositions per day, ranging from 1-77 en% fat, 3-45 en% protein, and 19-96 en% carbohydrate.
  
  
  RESULTS
  Selection, namely food choice that differs from random consumption, took place at breakfast in favour of carbohydrate, and at dinner in favour of fat. Habituation, namely a decreased response on the same stimulus, occurred after the fourth exposure to a single macronutrient buffet. For protein this was expressed as a significantly increased satiety score per kJ ingested; for fat as a significant drop in hedonic value; for carbohydrate as a significantly increased desire for a different taste, all (P < 0.05). Compensation, i.e. a correction afterwards for an earlier unusual macronutrient composition, resulting in a close to usual macronutrient composition of 24 h food intake, occurred at dinner, for a previous unusually low fat and high carbohydrate intake.
  
  
  CONCLUSIONS
  A pattern of macronutrient intake was achieved by selection and compensation. Habituation occurred at the fourth exposure of a single macronutrient.
authors.affiliation: University of Limburg, Maastricht, Heerlen, The Netherlands.
authors.forename: M S
authors.initials: MS
authors.lastname: Westerterp-Plantenga
authors.forename: M J
authors.initials: MJ
authors.lastname: IJedema
authors.forename: N E
authors.initials: NE
authors.lastname: Wijckmans-Duijsens
mesh_terms: D000328:Adult; D004032:Diet; D015930:Diet Records; D002149:Energy Intake; D005260:Female; D005518:Food Preferences; D006801:Humans; D008875:Middle Aged; D015596:Nutrition Assessment; D009753:Nutritive Value; D009765:Obesity; D011897:Random Allocation