title: Headspace GC/MS testing for chlorodifluoromethane in two fatal cases.
abstract: Two cases of lethal poisoning due to chlorodifluoromethane (Freon 22) inhalation are described. The fluorocarbon was determined in biological tissues by headspace gas chromatography/mass spectrometry. Ions monitored were m/z 67, 86 and 51, the latter being used for quantification. Blood concentrations were 26.0 and 37.1 microliters/ml. In both cases, the drug was also identified in urine, vitreous humor and bile, but in much lower concentrations.
authors.affiliation: Institut de Médecine, Légale, Strasbourg, France.
authors.forename: P
authors.initials: P
authors.lastname: Kintz
authors.forename: E
authors.initials: E
authors.lastname: Baccino
authors.forename: A
authors.initials: A
authors.lastname: Tracqui
authors.forename: P
authors.initials: P
authors.lastname: Mangin
mesh_terms: D000062:Accidents, Occupational; D005617:Chlorofluorocarbons, Methane / Q000493:pharmacokinetics / Q000506:poisoning*; D005554:Forensic Medicine; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008297:Male; D011041:Poisoning / Q000473:pathology
chemical_list: D005617:Chlorofluorocarbons, Methane; C009755:fluorocarbon 22