[Trimethoprim-sulphamethoxazole-induced meningitis].
Drug-induced meningitis is rarely included in the differential diagnosis of aseptic (usually recurrent) meningitis. A 74-year-old man who suffered from recurrent aseptic meningitis following re-exposures to trimethoprim-sulphamethoxazole (Resprim) is presented. The clinical and laboratory findings resembled those found in bacterial meningitis, excluding normal glycorrachia. Extensive microbiological, serologic and imaging studies did not disclose any relevant findings. All symptoms and signs resolved rapidly following drug withdrawal, and findings on follow-up lumbar puncture were normal.
Poles
L
L
Medical Dept. E, Beilinson Medical Center, Petah Tikva.
Theodor
E
E
D000368:Aged; D000890:Anti-Infective Agents / Q000009:adverse effects*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008581:Meningitis / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000009:adverse effects*
D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination