title: Autoimmune polyendocrinopathy--candidiasis--ectodermal dystrophy (APECED).
abstract: APECED, an autosomal recessive disease manifests itself as a widely variable combination of three groups of components: 1) autoimmune destruction of tissues, predominantly endocrine glands, 2) chronic superficial candidiasis, and 3) ectodermal dystrophy. Clinical and basic information obtained from Finnish series of 72 patients is reviewed.
authors.affiliation: Children's Hospital, University of Helsinki, Finland.
authors.forename: J
authors.initials: J
authors.lastname: Perheentupa
mesh_terms: D000224:Addison Disease / Q000276:immunology; D000293:Adolescent; D000328:Adult; D015551:Autoimmunity / Q000276:immunology; D002177:Candidiasis / Q000276:immunology; D002648:Child; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000276:immunology; D005260:Female; D006801:Humans; D007011:Hypoparathyroidism / Q000276:immunology; D007037:Hypothyroidism / Q000276:immunology; D015994:Incidence; D007223:Infant; D008297:Male; D008875:Middle Aged; D016884:Polyendocrinopathies, Autoimmune / Q000235:genetics / Q000276:immunology*