Antibiotic prophylaxis in prosthetic penile surgery: critical assessment of results in 75 consecutive patients.
OBJECTIVE
Antibiotic prophylaxis in prosthetic surgery was administered prospectively according an original protocol. Routine pre-operative preparation included also scrupulous, repeated disinfection of the skin of the genital and perineal region.


METHODS
Vancomycin 500 mg i.v. every 6 h on the day of surgery and gentamicin 1 mg/kg i.v. every 8 h on the day of surgery and for the following 48 h were administered to 75 consecutive patients. Overall 87 prosthetic devices were implanted. The patients were evaluated at 6 weeks and at 6 months after surgery.


RESULTS
No infection was observed.


CONCLUSIONS
Support from this study to antibiotic prophylaxis in penile prosthetic surgery is uncertain. The importance of scrupulous routine pre-operative preparation is probably underestimated.
Maffezzini
M
M
Institute of Urology, University di Trieste, Italy.
Capone
M
M
Ciampalini
S
S
De Stefani
S D
SD
Simonato
A
A
Carmignani
G
G
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D005069:Evaluation Studies as Topic; D005839:Gentamicins / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D015917:Penile Prosthesis; D010413:Penis / Q000601:surgery*; D011446:Prospective Studies; D016459:Prosthesis-Related Infections / Q000517:prevention & control*; D014640:Vancomycin / Q000627:therapeutic use*
D000900:Anti-Bacterial Agents; D005839:Gentamicins; D014640:Vancomycin