title: Direct activity of recombinant human lactoferrin against Helicobacter pylori.
abstract: We report the activity of recombinant human lactoferrin against Helicobacter pylori. Lactoferrin exerted a time- and dose-dependent action against 8 of the 13 clinical isolates of H. pylori tested in vitro. These results highlight a potential therapeutic use for lactoferrin against H.pylori infection.
authors.affiliation: Department of Medicine, Veterans Affairs Medical Center, Houston, Texas, USA.
authors.forename: S
authors.initials: S
authors.lastname: Miehlke
authors.forename: R
authors.initials: R
authors.lastname: Reddy
authors.forename: M S
authors.initials: MS
authors.lastname: Osato
authors.forename: P P
authors.initials: PP
authors.lastname: Ward
authors.forename: O M
authors.initials: OM
authors.lastname: Conneely
authors.forename: D Y
authors.initials: DY
authors.lastname: Graham
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016480:Helicobacter pylori / Q000187:drug effects*; D006801:Humans; D007781:Lactoferrin / Q000235:genetics / Q000494:pharmacology*; D011994:Recombinant Proteins / Q000235:genetics / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D011994:Recombinant Proteins; D007781:Lactoferrin