title: Endoscopic closure of postsurgical anterior cranial fossa cerebrospinal fluid leaks.
abstract: OBJECTIVE
  The primary objective of this study is to present an alternative technique to closure of anterior cranial fossa cerebrospinal fluid (CSF) leaks. This study also serves to review our experience with our technique and presents some technical "tricks" we have learned through experience.
  
  
  METHODS
  The design of this study is a clinical chart review. The setting is an academic medical center.
  
  
  RESULTS
  Eight patients were referred for closure of postsurgical CSF leaks. Seven of eight patients underwent closure with one attempt and closure was achieved after a second attempt in one patient. Follow-up ranged from 1.5 to 4.0 years. There were no complications. No patient developed an acute or delayed episode of meningitis.
  
  
  CONCLUSIONS
  The technique of endoscopic closure of a CSF leak is a safe and effective means for closure of a postsurgical anterior cranial fossa CSF fistula when performed by an experienced operator.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, University of California, Irvine Medical Center, Orange, USA.
authors.forename: T F
authors.initials: TF
authors.lastname: Kelley
authors.forename: J A
authors.initials: JA
authors.lastname: Stankiewicz
authors.forename: J M
authors.initials: JM
authors.lastname: Chow
authors.forename: T C
authors.initials: TC
authors.lastname: Origitano
authors.forename: J
authors.initials: J
authors.lastname: Shea
mesh_terms: D000236:Adenoma / Q000601:surgery; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000601:surgery; D002559:Cerebrospinal Fluid Rhinorrhea / Q000175:diagnosis / Q000601:surgery*; D002817:Chordoma / Q000601:surgery; D003397:Craniopharyngioma / Q000601:surgery; D003399:Craniotomy; D004724:Endoscopy; D005260:Female; D006801:Humans; D007016:Hypophysectomy; D008297:Male; D008577:Meningeal Neoplasms / Q000601:surgery; D008579:Meningioma / Q000601:surgery; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000601:surgery; D011183:Postoperative Complications / Q000175:diagnosis / Q000601:surgery*; D012086:Reoperation; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome