title: Prenatal biochemical diagnostics of inborn developmental defects.
abstract: Screening of pathological pregnancies with the use of biochemical markers determined in maternal serum is now widely accepted as a useful procedure. In our experience, the main contribution is a finding of abnormal values of one or more of the markers, which will advise gynecologist upon a possibility of a risk pregnancy.
authors.affiliation: 1st Department of Medical Chemistry and Biochemistry, Charles University, Praha, Czech Republic.
authors.forename: I
authors.initials: I
authors.lastname: Malbohan
authors.forename: L
authors.initials: L
authors.lastname: Fialová
authors.forename: L
authors.initials: L
authors.lastname: Mikulíková
authors.forename: Z
authors.initials: Z
authors.lastname: Hájek
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood*; D006063:Chorionic Gonadotropin / Q000097:blood; D002887:Chromosomes, Human, Pair 18; D004314:Down Syndrome / Q000097:blood / Q000175:diagnosis; D005260:Female; D006801:Humans; D009436:Neural Tube Defects / Q000097:blood / Q000175:diagnosis; D011247:Pregnancy; D011268:Pregnancy-Specific beta 1-Glycoproteins / Q000032:analysis; D011296:Prenatal Diagnosis; D014314:Trisomy; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D015415:Biomarkers; D006063:Chorionic Gonadotropin; D011268:Pregnancy-Specific beta 1-Glycoproteins; D000509:alpha-Fetoproteins