title: Widespread ectopic neuropeptide-Y immunoreactivity in contralateral mossy fibres after a unilateral intrahippocampal kainic acid injection in the rat.
abstract: Granule cells of the dentate gyrus can express neuropeptide-Y (NPY) in several models of epilepsy involving limbic seizures, however, the nature of this ectopic expression is not well understood at present. We have studied the expression of NPY-immunoreactivity in mossy fibres contralateral to a unilateral intrahippocampal injection of kainic acid and report that ectopic mossy fibre NPY-immunoreactivity is observed throughout the contralateral hippocampus.
authors.affiliation: Laboratoire de Neurobiologie et Neuro-imagerie, Expérimentales, Université de Bordeaux II 146, France. dominiquelurton100646.3446@compuserve.com
authors.forename: D
authors.initials: D
authors.lastname: Lurton
authors.forename: M
authors.initials: M
authors.lastname: Coussemacq
authors.forename: P
authors.initials: P
authors.lastname: Barrow
authors.forename: L E
authors.initials: LE
authors.lastname: Sundstrom
authors.forename: A
authors.initials: A
authors.lastname: Rougier
mesh_terms: D000818:Animals; D000918:Antibody Specificity; D004827:Epilepsy / Q000503:physiopathology; D018690:Excitatory Amino Acid Agonists / Q000494:pharmacology*; D006624:Hippocampus / Q000737:chemistry* / Q000166:cytology / Q000187:drug effects; D007150:Immunohistochemistry; D007608:Kainic Acid / Q000494:pharmacology*; D008297:Male; D008845:Microinjections; D009478:Neuropeptide Y / Q000032:analysis / Q000276:immunology*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D018690:Excitatory Amino Acid Agonists; D009478:Neuropeptide Y; D007608:Kainic Acid