Case report: fatal verapamil overdosage despite intensive therapy and use of high dose intravenous calcium.
Although the initial treatment of choice in calcium antagonist poisoning is calcium, there has been controversy over the optimal regime of its administration. The administration of prolonged or regular, high doses of calcium has been suggested. We report a fatal case of verapamil overdosage which did not respond to intensive therapy and very high doses of intravenous calcium, despite achieving extremely high serum calcium levels.
Li Saw Hee
F L
FL
Department of Cardiology, Walsgrave Hospital, Coventry, UK.
Lip
G Y
GY
D002118:Calcium / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D062787:Drug Overdose; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008875:Middle Aged; D014700:Verapamil / Q000506:poisoning*
D014700:Verapamil; D002118:Calcium