title: Palmar papillomatous lesions reminiscent of epidermal nevus in a case of focal dermal hypoplasia: a nosological consideration.
abstract: A 40-year-old woman with focal dermal hypoplasia had a palmar papillomatous lesion showing a linear arrangement and histopathological features compatible with a diagnosis of epidermal nevus. This unusual manifestation of focal dermal hypoplasia is difficult to categorize. Undoubtedly the lesion reflects functional X-chromosome mosaicism. Although the mechanism of lyonization may give rise to true epidermal nevi such as CHILD nevus, we prefer to classify the present skin lesion as a nevoid disorder and not as an epidermal nevus.
authors.affiliation: Department of Dermatology, University of Marburg, Germany.
authors.forename: P H
authors.initials: PH
authors.lastname: van der Steen
authors.forename: H
authors.initials: H
authors.lastname: Mittag
authors.forename: W
authors.initials: W
authors.lastname: Küster
authors.forename: R
authors.initials: R
authors.lastname: Happle
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D005489:Focal Dermal Hypoplasia / Q000145:classification / Q000235:genetics / Q000473:pathology*; D006225:Hand / Q000473:pathology*; D006229:Hand Dermatoses / Q000145:classification / Q000235:genetics / Q000473:pathology*; D006801:Humans; D009030:Mosaicism / Q000235:genetics; D009506:Nevus / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*; D014960:X Chromosome / Q000235:genetics