MR features of an intracerebellar chloroma.
Granulocytic sarcoma (chloroma) is a rare tumor almost always associated with leukemia. Intraaxial brain lesions are rare, and can mimic infection or primary neoplasm. This intracerebellar chloroma arose after autologous bone marrow transplantation in a 29-year-old woman with leukemia. On T1-weighted MR images, the lesion was isointense with gray matter, and enhanced homogeneously. On T2-weighted and proton density-weighted MR sequences, the center was isointense with gray matter and the periphery was isointense with white matter. The lesion's tendency to remain isointense on sequences with long repetition times is presumably attributable to the presence of myeloperoxidase.
Parker
K
K
Department of Radiology, Louisiana State University Medical Center, Shreveport 71130, USA.
Hardjasudarma
M
M
McClellan
R L
RL
Fowler
M R
MR
Milner
J W
JW
D000328:Adult; D001706:Biopsy; D016026:Bone Marrow Transplantation; D002528:Cerebellar Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D007089:Image Enhancement; D007951:Leukemia, Myeloid / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000628:therapy; D008279:Magnetic Resonance Imaging; D009195:Peroxidase / Q000032:analysis; D015641:Radiography, Interventional; D014057:Tomography, X-Ray Computed; D014182:Transplantation, Autologous
D009195:Peroxidase