title: Intraventricular neuropeptide Y does not stimulate food intake in the baboon.
abstract: In the present study, we examined the ability of the orexigenic peptide neuropeptide Y (NPY) to stimulate feeding when administered into the lateral ventricle of baboons. No increase of either meal size or total daily food intake was observed over the dose range tested (1-30 micrograms). These results suggest that, in the baboon, NPY may not be an orexigen as it is in other species.
authors.affiliation: Department of Psychology, University of Washington, Seattle 98195, USA.
authors.forename: A J
authors.initials: AJ
authors.lastname: Sipols
authors.forename: D P
authors.initials: DP
authors.lastname: Figlewicz
authors.forename: R J
authors.initials: RJ
authors.lastname: Seeley
authors.forename: M
authors.initials: M
authors.lastname: Chavez
authors.forename: S C
authors.initials: SC
authors.lastname: Woods
authors.forename: D
authors.initials: D
authors.lastname: Porte
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D004435:Eating / Q000187:drug effects*; D007275:Injections, Intravenous; D008297:Male; D009478:Neuropeptide Y / Q000494:pharmacology*; D010215:Papio
chemical_list: D009478:Neuropeptide Y