Studies on the enhancement of the reactivity of the (Cys-25)-S-/(His159)-Im+H ion-pair of papain by deprotonation across pKa 4.
Pinitglang
S
S
Department of Biochemistry, Queen Mary & Westwield College, University of London, U.K.
Noble
M
M
Verma
C
C
Thomas
E W
EW
Brocklehurst
K
K
D001665:Binding Sites; D003545:Cysteine / Q000737:chemistry; D006639:Histidine / Q000737:chemistry; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D007477:Ions; D007700:Kinetics; D015394:Molecular Structure; D010206:Papain / Q000737:chemistry* / Q000378:metabolism*
D007477:Ions; D006639:Histidine; D010206:Papain; D003545:Cysteine