title: Serum sickness-like illness following streptokinase therapy. A case report.
abstract: We report a patient who developed a serum sickness-like illness characterized by fever, arthritis, haematuria and a purpuric eruption 7 days following streptokinase therapy for myocardial infarction. Blood tests demonstrated increased circulating immune complexes. The skin involvement resulted in extensive, painful cutaneous infarction with secondary bacterial infection. Serum sickness is an uncommon but recognized complication of streptokinase therapy.
authors.affiliation: St. John's Institute of Dermatology, St. Thomas' Hospital, London, UK.
authors.forename: J D
authors.initials: JD
authors.lastname: Creamer
authors.forename: J A
authors.initials: JA
authors.lastname: McGrath
authors.forename: M
authors.initials: M
authors.lastname: Webb-Peploe
authors.forename: N P
authors.initials: NP
authors.lastname: Smith
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy* / Q000473:pathology; D012713:Serum Sickness / Q000209:etiology* / Q000473:pathology; D012867:Skin / Q000473:pathology; D013300:Streptokinase / Q000009:adverse effects*; D015912:Thrombolytic Therapy
chemical_list: D013300:Streptokinase