title: Giant cell tumor (osteoclastoma) of the mandible: a diagnostic dilemma and a therapeutic challenge.
abstract: A recurrent giant cell lesion of bone 4.5 years after initial curettage from the mandibular body is described in a 40-year-old premenopausal female patient. Giant cell tumor is exceedingly rare in this location and histologically may be indistinguishable from giant cell reparative granuloma. The treatment rationale for this particular patient was extrapolated from the treatment of giant cell tumor in other more commonly involved bones. En bloc resection is indicated irrespective of the grade or stage of the tumor, provided satisfactory reconstruction can be achieved. The morbidity from tumor treatment should never, in any case, exceed the morbidity from the tumor itself.
authors.affiliation: Division of Plastic & Reconstructive Surgery, American University of Beirut-Medical Center, Lebanon.
authors.forename: B S
authors.initials: BS
authors.lastname: Atiyeh
authors.forename: A
authors.initials: A
authors.lastname: Tawil
authors.forename: I L
authors.initials: IL
authors.lastname: Kaddoura
authors.forename: A M
authors.initials: AM
authors.lastname: Zaatari
authors.forename: A M
authors.initials: AM
authors.lastname: Hamdan
mesh_terms: D000328:Adult; D005260:Female; D018212:Giant Cell Tumor of Bone / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008339:Mandibular Neoplasms / Q000473:pathology / Q000601:surgery*; D009364:Neoplasm Recurrence, Local