title: Acquired localized elastolysis associated with varicose veins.
abstract: Localized elastolysis refers to a group of heterogeneous conditions which includes cutis laxa. We report a form of localized and non-inflammatory elastolysis evocative of cutis laxa, localized to the anteromedial aspect of the left thigh and knee, acquired at the age of 8 years and associated with unilateral adjacent venous dilatations appearing at the age of 39 years. Our case is clinically and ultrastructurally compatible with cutis laxa. Localized forms of cutis laxa not preceded by inflammation are exceptional; localization on the leg has never been described. This clinical form of elastolysis calls into question the classification of acquired elastolysis. The adjacent varicose veins also raise the question of the risk of subcutaneous damage in this condition.
authors.affiliation: Department of Dermatology, Purpan Hospital, Toulouse, France.
authors.forename: P
authors.initials: P
authors.lastname: Bayle-Lebey
authors.forename: B
authors.initials: B
authors.lastname: Periole
authors.forename: G
authors.initials: G
authors.lastname: Daste
authors.forename: B
authors.initials: B
authors.lastname: Sans
authors.forename: M C
authors.initials: MC
authors.lastname: Marguery
authors.forename: F
authors.initials: F
authors.lastname: El Sayed
authors.forename: J
authors.initials: J
authors.lastname: Bazex
authors.forename: W A
authors.initials: WA
authors.lastname: Griffiths
mesh_terms: D000328:Adult; D003483:Cutis Laxa / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D007868:Leg Dermatoses / Q000150:complications* / Q000473:pathology; D012867:Skin / Q000473:pathology; D014648:Varicose Veins / Q000150:complications* / Q000473:pathology