title: Blood glucose normalization-induced haemolysis in three adolescents with type 1 diabetes mellitus at onset and unknown G-6-PD deficiency.
abstract: We present three adolescents unknown to be G-6-PD deficient who developed haemolytic anaemia after admission for diabetes at onset uncomplicated by ketoacidosis. These patients had no bacterial infections and had not ingested haemolytic drugs. The fall in glucose availability after the correction of hyperglycaemia is proposed as capable of inducing haemolysis in G-6-PD deficiency.
authors.affiliation: Department of Paediatrics, University of Parma, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Vanelli
authors.forename: L
authors.initials: L
authors.lastname: Lucentini
authors.forename: P
authors.initials: P
authors.lastname: Picco
authors.forename: R
authors.initials: R
authors.lastname: Galanello
authors.forename: G
authors.initials: G
authors.lastname: Chiari
authors.forename: B
authors.initials: B
authors.lastname: Adinolfi
authors.forename: M E
authors.initials: ME
authors.lastname: Street
mesh_terms: D000293:Adolescent; D000743:Anemia, Hemolytic / Q000209:etiology*; D001786:Blood Glucose / Q000378:metabolism*; D002648:Child; D004252:DNA Mutational Analysis; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000188:drug therapy / Q000378:metabolism; D005955:Glucosephosphate Dehydrogenase Deficiency / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D006029:Glycosuria; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use; D007657:Ketone Bodies / Q000652:urine; D008297:Male
chemical_list: D001786:Blood Glucose; D007328:Insulin; D007657:Ketone Bodies