title: Etiopathogenesis of cryptorchidism and male infertility.
abstract: A retrospective study was performed 2.60 +/- 1.14 years after ochidopexy on 124 patients with cryptorchidism. Complex spermatological, hormonal, and histomorphological investigations were carried out which demonstrated the existence of disturbances in the exo- and endocrine functions of the testes of these patients. The results juxtaposed to the ages when the orchidopexy was accomplished revealed the necessity of early surgical intervention prior to 5 years of age. After this age there were severe changes in the histomorphological characteristics of the testicular tissue.
authors.affiliation: Institute of Biology and Immunology of Reproduction, Department of Immunoneuroendocrinology, Sofia, Bulgaria.
authors.forename: P
authors.initials: P
authors.lastname: Tzvetkova
authors.forename: D
authors.initials: D
authors.lastname: Tzvetkov
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D003456:Cryptorchidism / Q000150:complications* / Q000503:physiopathology / Q000601:surgery; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007248:Infertility, Male / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D012189:Retrospective Studies; D013076:Sperm Count; D013081:Sperm Motility; D013737:Testis / Q000473:pathology; D013739:Testosterone / Q000097:blood
chemical_list: D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone