Nonsurgical cure of isolated cerebral mucormycosis in an intravenous drug user.
The case of a 30-year-old, female, HIV-positive intravenous drug user who suffered from isolated cerebral mucormycosis is reported. Treatment with amphotericin B at an accumulative dose of 5.5 grams led to significant recovery, and there was no recurrence of disease over a follow-up period of six months. Patients with isolated cerebral mucormycosis in whom surgery would be a high-risk or impossible procedure could be managed medically with prolonged courses of intravenous amphotericin B.
Blázquez
R
R
Clinical Microbiology and Infectious Diseases Division, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Pinedo
A
A
Cosín
J
J
Miralles
P
P
Lacruz
C
C
Bouza
E
E
D000328:Adult; D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001921:Brain / Q000382:microbiology / Q000473:pathology; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D009091:Mucormycosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011859:Radiography; D015819:Substance Abuse, Intravenous / Q000150:complications / Q000382:microbiology / Q000821:virology
D000935:Antifungal Agents; D000666:Amphotericin B