Cystic renal disease and tuberous sclerosis in infants.
We describe 2 infants who presented with autosomal dominant-like polycystic kidney disease. Evaluation revealed that both children had tuberous sclerosis, with resulting cystic kidney disease. This diagnosis should be suspected in infants who present with bilateral, large renal cysts, and no family history of autosomal dominant polycystic kidney disease.
Glazier
D B
DB
Department of Surgery, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903-0019, USA.
Fleisher
M H
MH
Cummings
K B
KB
Barone
J G
JG
D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D016891:Polycystic Kidney, Autosomal Dominant / Q000209:etiology*; D014402:Tuberous Sclerosis / Q000150:complications*