title: Complications in paediatric craniopharyngioma treatment.
abstract: Forty-eight consecutive children treated for craniopharyngioma at the Juan P. Garrahan National Paediatric Hospital (Buenos Aires, Argentina) from 1988 to 1994 are described. Complications of patients undergoing total resection alone and those undergoing subtotal or partial resection plus radiotherapy were compared. Survival time and quality of life proved more satisfactory in the former group, as there were no recurrences. In contrast, among the latter patients, 53% suffered relapses. Endocrinological complications were similar in the two groups. Postsurgical subdural haematomas were quite frequent and eight patients required treatment for intracranial hypertension. Vascular complications, though less common, led to high morbidity and mortality. There was a considerable incidence of shunt malfunction (80%), arguing against placement of a preoperative shunt, which tended besides to foster postsurgical subdural haematomas.
authors.affiliation: Juan P. Garrahan National Paediatric Hospital, Buenos Aires, Argentina.
authors.forename: G
authors.initials: G
authors.lastname: Zuccaro
authors.forename: R
authors.initials: R
authors.lastname: Jaimovich
authors.forename: B
authors.initials: B
authors.lastname: Mantese
authors.forename: J
authors.initials: J
authors.lastname: Monges
mesh_terms: D000293:Adolescent; D000328:Adult; D002557:Cerebrospinal Fluid Shunts; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003397:Craniopharyngioma / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007016:Hypophysectomy; D007223:Infant; D008297:Male; D010910:Pituitary Irradiation; D010911:Pituitary Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology* / Q000401:mortality; D011788:Quality of Life; D018714:Radiotherapy, Adjuvant; D015996:Survival Rate; D016896:Treatment Outcome