title: Triple marker screening in native Japanese women.
abstract: Prenatal screening using the maternal serum markers alpha-fetoprotein, human chorionic gonadotropin, and unconjugated oestriol was investigated in a native Japanese population. Comparison with a Caucasian U.S. population revealed differences which led to modification of the generally used equations for risk calculations. Prenatal screening was shown to be clinically useful.
authors.affiliation: Jikei University School of Medicine, Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Onda
authors.forename: M
authors.initials: M
authors.lastname: Kitagawa
authors.forename: O
authors.initials: O
authors.lastname: Takeda
authors.forename: H
authors.initials: H
authors.lastname: Sago
authors.forename: K
authors.initials: K
authors.lastname: Kubonoya
authors.forename: K
authors.initials: K
authors.lastname: Iinuma
authors.forename: L A
authors.initials: LA
authors.lastname: Bradley
authors.forename: J A
authors.initials: JA
authors.lastname: Canick
authors.forename: N E
authors.initials: NE
authors.lastname: Krasikov
authors.forename: N R
authors.initials: NR
authors.lastname: Ponting
authors.forename: R E
authors.initials: RE
authors.lastname: Grier
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood*; D001835:Body Weight; D006063:Chorionic Gonadotropin / Q000097:blood; D004314:Down Syndrome / Q000097:blood / Q000175:diagnosis*; D004964:Estriol / Q000097:blood; D005260:Female; D005865:Gestational Age; D006801:Humans; D007564:Japan; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014481:United States; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D015415:Biomarkers; D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins; D004964:Estriol