Practical experience and issues in designing and performing population pharmacokinetic/pharmacodynamic studies.
An expert meeting to discuss issues relating to the design of population pharmacokinetic/pharmacodynamic (PK/PD) studies was held in Brussels in March 1995, under the auspices of the European Co-operation in Science and Technology (COST), Medicine (B1) programme. The purpose of the meeting was to discuss the experts' experience in designing and performing population PK/PD studies. The topics discussed were current practice, logistical issues, ensuring the accuracy of data, covariate assessment, communication, and protocol design.
Aarons
L
L
Department of Pharmacy, University of Manchester, UK.
Balant
L P
LP
Mentre
F
F
Morselli
P L
PL
Rowland
M
M
Steimer
J L
JL
Vozeh
S
S
D001530:Belgium; D002986:Clinical Trials as Topic; D010599:Pharmacokinetics; D012107:Research Design