title: Viral inhibition of apoptosis.
abstract: Viral propagation is limited both by the host immune response and by apoptosis of infected cells. Viruses circumvent apoptosis by different mechanisms: direct inhibition of particular proteases involved in cell death, stimulation of anti-death pathways or regulation of the activity of transcription factors monitoring cell survival.
authors.affiliation: Laboratoire de Biologie Moléculaire et Cellulaire, UMR 49 CNRS, ENS Lyon, France. Germain.Gillet@cri.ens-lyon.fr
authors.forename: G
authors.initials: G
authors.lastname: Gillet
authors.forename: G
authors.initials: G
authors.lastname: Brun
mesh_terms: D000818:Animals; D017209:Apoptosis; D003546:Cysteine Endopeptidases; D015853:Cysteine Proteinase Inhibitors; D005786:Gene Expression Regulation; D008954:Models, Biological; D019253:Proto-Oncogene Proteins c-bcl-2; D014158:Transcription, Genetic; D014780:Viruses / Q000254:growth & development* / Q000378:metabolism
chemical_list: D015853:Cysteine Proteinase Inhibitors; D019253:Proto-Oncogene Proteins c-bcl-2; D003546:Cysteine Endopeptidases