Treatment of recurrent hemoptysis in a child with cystic fibrosis by repeated bronchial artery embolizations and long-term tranexamic acid.
The course of a 12-year-old girl with cystic fibrosis (CF) and with recurrent hemoptysis since age 8 years is described. Conservative measures failed to control her bleeding. Hemoptysis was only partially controlled by repeated bronchial arterial embolizations. However, the addition of tranexamic acid (TXA) resulted in complete cessation of bleeding. Attempts to withdraw TXA therapy resulted in recurrence of hemoptysis; this patient has, therefore, been continuously maintained on this therapy for the past 4 years. No side effects of long-term TXA treatment have been noted.
Wong
L T
LT
Department of Paediatrics, University of British Columbia, Vancouver, Canada.
Lillquist
Y P
YP
Culham
G
G
DeJong
B P
BP
Davidson
A G
AG
D000933:Antifibrinolytic Agents / Q000627:therapeutic use*; D001981:Bronchial Arteries; D002648:Child; D003550:Cystic Fibrosis / Q000150:complications* / Q000000981:diagnostic imaging; D004621:Embolization, Therapeutic; D005260:Female; D006469:Hemoptysis / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D006801:Humans; D011859:Radiography; D012008:Recurrence; D013997:Time Factors; D014148:Tranexamic Acid / Q000627:therapeutic use*
D000933:Antifibrinolytic Agents; D014148:Tranexamic Acid