Tubercidin analogs from the ascidian Didemnum voeltzkowi.
Two new 5'-deoxypyrrolo[2,3-d]pyrimidine (7-deazapurine) nucleosides, 5'-deoxytubercidin and 5'-deoxy-3-bromotubercidin, were identified from the ascidian Didemnum voeltzkowi. Two known anomers of 5'-deoxy-3-iodotubercidin were also purified from the extract. Assignments were made on the basis of 1H and 13C chemical shifts as well as HPLC-MS experiments.
Department of Medicinal Chemistry, University of Utah, Salt Lake City 84112, USA.
S S
SS
Mitchell
S C
SC
Pomerantz
G P
GP
Concepción
C M
CM
Ireland
D000818:Animals; D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D009705:Nucleosides / Q000737:chemistry / Q000302:isolation & purification; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014372:Tubercidin / Q000031:analogs & derivatives* / Q000302:isolation & purification*; D014561:Urochordata / Q000737:chemistry*
D009705:Nucleosides; D014372:Tubercidin