The type-I interferon receptor. The long and short of it.
The type-I interferon receptor is a multisubunit receptor of the cytokine receptor superfamily. The production of specific monoclonal antibodies against the receptor and the cloning of different receptor subunits have contributed to understanding the type-I interferon receptor structure and function. The present article analyzes these new advances and the role of the different receptor subunits in type-I interferon signaling.
Department of Pathology, University of Tennessee, Memphis 38163, USA.
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Domanski
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Colamonici
D001665:Binding Sites; D005544:Forecasting; D006801:Humans; D008565:Membrane Proteins; D010766:Phosphorylation; D011485:Protein Binding; D011506:Proteins / Q000378:metabolism; D053633:Receptor, Interferon alpha-beta; D017471:Receptors, Interferon / Q000737:chemistry* / Q000145:classification / Q000378:metabolism*; D015398:Signal Transduction
D008565:Membrane Proteins; D011506:Proteins; D017471:Receptors, Interferon; D053633:Receptor, Interferon alpha-beta