Occlusion of unilateral carotid artery in Down syndrome.
The association between moyamoya phenomena and Down syndrome (DS) is reported in the literature. This paper reports a case of DS, which at age 9 presented right hemiparesis, secondary to the occlusion of the left internal carotid artery; cerebral angiography (CAG) showed a collateral circulation that mimicks the moyamoya phenomenon. Clinical recovery was almost complete; a second CAG after 15 months showed a persistent occlusion of the left internal carotid artery and an opacification of the left middle cerebral artery from abnormal vessels; but the collateral circulation is not enhanced. This case proves that in DS cerebrovascular occlusions may present moyamoya-like phenomena. These differ however from the true moyamoya disease in a number of aspects: the arterial occlusion is unilateral, the evolution is favorable and revascularization does not occur through the peculiar abnormal vessels of the moyamoya syndrome.
Gaggero
R
R
Division of Child Neuropsychiatry, Istituto G. Gaslini, Genoa, Italy.
Donati
P T
PT
Curia
R
R
De Negri
M
M
D000792:Angiography; D001157:Arterial Occlusive Diseases / Q000150:complications* / Q000175:diagnosis; D001921:Brain / Q000098:blood supply; D002339:Carotid Arteries / Q000473:pathology*; D002340:Carotid Artery Diseases / Q000150:complications*; D002561:Cerebrovascular Disorders / Q000150:complications; D002648:Child; D003937:Diagnosis, Differential; D004314:Down Syndrome / Q000150:complications* / Q000473:pathology; D006801:Humans; D009072:Moyamoya Disease / Q000175:diagnosis