Successful treatment of molluscum contagiosum in the immunosuppressed adult with topical injection of streptococcal preparation OK-432.
A 37-year-old Japanese woman received an anticancer drug for 5 years following resection of mammary cancer and then developed widespread mollusca contagiosa, which we considered to be caused by immunosuppression induced by the chemotherapy. Because OK-432 (penicillin-treated and heat-treated lyophilized powder by a substrain of Streptococcus pyogenes A) was expected to be effective for immunosuppression, we tried its topical injection. The skin lesions disappeared almost completely within three months. OK-432 therapy is considered hopeful for treating viral skin diseases, even in immunosuppressed patients.
Inui
S
S
Department of Dermatology, Osaka University, School of Medicine, Japan.
Asada
H
H
Yoshikawa
K
K
D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000150:complications / Q000276:immunology*; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007271:Injections, Intradermal; D008976:Molluscum Contagiosum / Q000150:complications / Q000188:drug therapy*; D010844:Picibanil / Q000008:administration & dosage* / Q000627:therapeutic use
D000970:Antineoplastic Agents; D010844:Picibanil