Use of rhG-CSF in the collection of peripheral blood stem cells for autologous blood stem cell transplantation in acute myeloblastic leukemia.
The use of recombinant granulocyte colony-stimulating factor (rhG-CSF) alone is attractive for the collection of peripheral blood stem cells (PBSC) in several malignancies. In acute myeloblastic leukemia (AML), not enough experience has been gained with rhG-CSF and leukapheresis is more common after recovery from antileukemia chemotherapy. This is the case report of a patient who received rhG-CSF alone to mobilize stem cells where the cells collected in the leukapheresis bag had a blastic immunophenotype.
Servicio de Hematología, Hospital Virgen de las Nieves, Granada, Spain.
M
M
Jurado
C
C
Delgado
A
A
Moratalla
D
D
Casero
S
S
Oyonarte
J M
JM
de Pablos
D016179:Granulocyte Colony-Stimulating Factor / Q000009:adverse effects / Q000627:therapeutic use*; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006412:Hematopoietic Stem Cells / Q000187:drug effects* / Q000276:immunology; D006801:Humans; D007937:Leukapheresis / Q000379:methods*; D015470:Leukemia, Myeloid, Acute / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D014411:Neoplastic Stem Cells / Q000187:drug effects / Q000276:immunology; D010641:Phenotype; D011994:Recombinant Proteins; D014182:Transplantation, Autologous
D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor