Gorlin's syndrome: main features and recent advances.
Gorlin's syndrome embraces a constellation of cranial, maxillofacial and systemic disorders, which may have a serious effect on both the morbidity and mortality of the patients. Recent work has identified that the disorder is caused by a mutation within a tumour suppressor gene.
Crean
S J
SJ
Department of Maxillofacial Surgery, Eastman Dental Institute, London.
Cunningham
S J
SJ
D001478:Basal Cell Nevus Syndrome / Q000150:complications / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D016147:Genes, Tumor Suppressor / Q000235:genetics; D006801:Humans; D008134:Long-Term Care; D009017:Morbidity; D009154:Mutation / Q000235:genetics