Determination of analytical form of system weighting function.
This paper presents the determination of the analytical form of the weighting function of the three following complex multicomponent systems: 1) the system describing human pharmacokinetics of pentacaine after oral administration; 2) the system describing the hepatal elimination of indocyanine green in pig, and 3) the system describing the fate of indocyanine green in human esophageal varixes. The determination of the weighting function is based on the system transfer function and the technique of the partial-fraction inversion.
Durisová
M
M
Institute of Experimental Pharmacology, Slovak Academy of Sciences, Bratislava, Slovak Republic.
Dedík
L
L
D000284:Administration, Oral; D000818:Animals; D000897:Anti-Ulcer Agents / Q000008:administration & dosage / Q000493:pharmacokinetics*; D002219:Carbamates / Q000008:administration & dosage / Q000493:pharmacokinetics*; D004947:Esophagus / Q000378:metabolism*; D006801:Humans; D007208:Indocyanine Green / Q000378:metabolism*; D008962:Models, Theoretical; D012984:Software; D013552:Swine
D000897:Anti-Ulcer Agents; D002219:Carbamates; C010618:pentacaine; D007208:Indocyanine Green