Bullous mastocytosis in an infant associated with the use of a nonprescription cough suppressant.
Bullous mastocytosis is an unusual expression of mastocytosis typically seen in young children, and many causes of the acute mast cell degranulation with bulla formation have been identified. We report a 6-month-old boy with urticaria pigmentosa and an extensive bullous eruption associated with the ingestion of a nonprescription cough suppressant containing dextromethorphan. The pathogenesis of mastocytosis and the care of patients with this disease are discussed.
Department of Dermatology, Medical University of South Carolina, Charleston 29425-2215, USA.
J
J
Cook
M
M
Stith
E E
EE
Sahn
D000996:Antitussive Agents / Q000009:adverse effects*; D004205:Cromolyn Sodium / Q000627:therapeutic use; D003915:Dextromethorphan / Q000009:adverse effects*; D003875:Drug Eruptions / Q000188:drug therapy / Q000209:etiology*; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D004366:Nonprescription Drugs / Q000009:adverse effects*; D014582:Urticaria Pigmentosa / Q000150:complications* / Q000188:drug therapy
D000996:Antitussive Agents; D006634:Histamine H1 Antagonists; D004366:Nonprescription Drugs; D003915:Dextromethorphan; D004205:Cromolyn Sodium