Liver transplantation for Langerhans' cell histiocytosis--a case report and literature review.
Langerhans' cell histiocytosis (LCH) is a rare disorder of unknown etiology and pathogenesis. End-stage chronic liver disease is one presentation and orthotopic liver transplantation (OLT) has been reported in 17 cases, with variable resolution of LCH lesions postoperatively. We report a case of multisystem LCH with end-stage liver disease treated by OLT and review the overall results of OLT for children with LCH.
Melendez
H V
HV
Liver Transplant Surgical Service and Department of Child Health, King's College Hospital, London, United Kingdom.
Dhawan
A
A
Mieli-Vergani
G
G
Rela
M
M
Heaton
N D
ND
Pritchard
J
J
Mowat
A
A
D002675:Child, Preschool; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000453:epidemiology / Q000209:etiology / Q000601:surgery*; D006801:Humans; D015994:Incidence; D007223:Infant; D016031:Liver Transplantation