Intravenous gammaglobulin therapy of Satoyoshi syndrome.
Satoyoshi syndrome is a very rare disease of unknown etiology, characterized by intermittent painful muscle spasms, alopecia, multiple epiphyseal changes, diarrhea and endocrine disorders. We administered intravenous gammaglobulin to a 7-year-old girl with Satoyoshi syndrome. Frequency of muscle spasms and the titers of antinuclear antibody and anti-DNA antibody decreased. This is the first report of gammaglobulin therapy of Satoyoshi syndrome. We suggest that this illness could be related to an autoimmune mechanism.
Division of Neurology, Saitama Children's Medical Center, Japan.
J
J
Arita
S
S
Hamano
T
T
Nara
K
K
Maekawa
D000505:Alopecia / Q000628:therapy*; D002357:Cartilage Diseases / Q000473:pathology / Q000628:therapy*; D002648:Child; D005260:Female; D006132:Growth Plate / Q000473:pathology; D006801:Humans; D007167:Immunotherapy; D008279:Magnetic Resonance Imaging; D009128:Muscle Spasticity / Q000473:pathology / Q000628:therapy*; D013577:Syndrome; D005719:gamma-Globulins / Q000008:administration & dosage
D005719:gamma-Globulins