Obesity and metabolic disorders in adults with lower limb amputation.
Anthropometric and biochemical research was conducted on 94 subjects with various levels of lower limb amputation. The purpose of the work was to investigate the features of obesity progression and disorders of cholesterin metabolism, as well as to develop adequate training exercises. Anthropometric research was conducted by calipermetry; the biochemical research was done by various methods to determine exempt and total cholesterin and triglycerides in the blood serum. The research establishes the frequency of obesity progression relative to the level of amputation, as well as the features of the excessive body mass. Type 11A hyperlipoproteidemia was evident. It is characterized by rapid progress of atherosclerotic vascular disease and coronary disease (CD). Cyclic and acyclic exercises were developed for prophylaxis and therapy. Anthropometric research on the determination of body fat mass was conducted on 68 subjects with various levels of lower limb amputation. The nondirect method of measuring skin folds of several parts of the body was used to determine the extent of lipogenesis. Biochemical research of cholesterin metabolism was conducted on 26 subjects with lower limb amputation (a different group). Anthropometric research revealed an increase of body fat mass directly related to the level of amputation. The largest amount of fat in the body mass was noted for the subjects with bilateral transfemoral (above-knee) amputation or transfemoral plus transtibial (below-knee) amputation. Both groups averaged 25.9%. The body fat mass increased chiefly in the subcutaneous fat. Increase of the internal fat mass was less noticeable. The frequency of obesity progression in subjects with unilateral transtibial amputation equaled 37.9%; in subjects with transfemoral amputation, 48.0%; and in subjects with bilateral transfemoral or transfemoral plus transtibial amputation, 64.2%. Young subjects demonstrated obesity progression during the first year after amputation. Biochemical research revealed changes in the cholesterin fractions typical for type 11A hyperlipoproteidemia. This type of hyperlipoproteidemia is often accompanied by atherosclerotic vascular diseases and CD. On the basis of the research and clinical observation, exercises were developed aimed at prophylaxis and treatment of the revealed changes. Exercises are described for subjects with various levels of lower limb amputation when using exercise machines and when swimming.
Saint Petersburg Scientific Research Institute of Prosthetics, Russia.
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Kurdibaylo
D000328:Adult; D000671:Amputation, Surgical / Q000534:rehabilitation*; D000704:Analysis of Variance; D000886:Anthropometry; D005081:Exercise Therapy / Q000379:methods; D006801:Humans; D006951:Hyperlipoproteinemias / Q000209:etiology / Q000378:metabolism*; D007866:Leg; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000503:physiopathology; D015203:Reproducibility of Results; D012307:Risk Factors; D016896:Treatment Outcome