Aggressive management of intra-arterial Temazepam injection.
Intravenous injection of the oral formulation of Temazepam is a common form of drug abuse. At the request of the Home Office, manufacturers have developed solid dose forms to replace the liquid filled capsules, but a number of cases of accidental intra-arterial injection of the new formulation have been reported, with varying management strategies advocated. A case is presented where prompt aggressive management using surgical and pharmacological measures resulted in complete limb salvage. Previous reported cases and management options are discussed.
Russell
I D
ID
Surgical Department, Cambridge Military Hospital, Aldershot, Hants.
Kane
G G
GG
Royle
C A
CA
Jackson
D S
DS
D000328:Adult; D001916:Brachial Artery; D002626:Chemistry, Pharmaceutical; D003161:Compartment Syndromes / Q000139:chemically induced; D011464:Epoprostenol / Q000627:therapeutic use; D006801:Humans; D007269:Injections, Intra-Arterial / Q000009:adverse effects*; D008297:Male; D009543:Nifedipine / Q000627:therapeutic use; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D016879:Salvage Therapy; D015819:Substance Abuse, Intravenous / Q000150:complications / Q000628:therapy*; D013693:Temazepam; D014665:Vasodilator Agents / Q000627:therapeutic use
D010975:Platelet Aggregation Inhibitors; D014665:Vasodilator Agents; D013693:Temazepam; D011464:Epoprostenol; D009543:Nifedipine