Influence of growth selection in turkeys on resistance to Pasteurella multocida.
Four lines of turkeys, a randombred control (RBC2) started in 1966 and three sire lines (F, A, and B), were challenged with a field isolate of Pasteurella multocida (capsular serogroup A, somatic serotype 3, 4) at 6 wk of age. Line F, a subline of the RBC2 line, was selected for 28 generations for increased 16-wk BW and Lines A and B were primary breeding sire lines from two commercial breeders. Each bird was inoculated subcutaneously in the back of the neck with 1.2 x 10(7) washed bacteria. Mortality following challenge with P. multocida was higher in the sire lines (54 to 65%) than in the RBC2 line (26%). There was no significant difference in mortality among sire lines following challenge. These results suggest that the increased susceptibility to P. multocida in the F line in comparison to its control may be due to genetic changes resulting from selection for increased BW in this line.
Department of Animal Sciences, Ohio Agricultural Research and Development Center, Ohio State University, Wooster 44691, USA.
K E
KE
Nestor
Y M
YM
Saif
J
J
Zhu
D O
DO
Noble
D000375:Aging / Q000276:immunology; D000818:Animals; D000907:Antibodies, Bacterial / Q000276:immunology / Q000378:metabolism; D001947:Breeding; D005260:Female; D007113:Immunity, Innate / Q000235:genetics*; D008297:Male; D010326:Pasteurella Infections / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary*; D016979:Pasteurella multocida / Q000276:immunology*; D011201:Poultry Diseases / Q000276:immunology / Q000401:mortality / Q000517:prevention & control*; D012641:Selection, Genetic; D014422:Turkeys / Q000235:genetics / Q000254:growth & development / Q000276:immunology*
D000907:Antibodies, Bacterial