Effect on intraerythrocytic Anaplasma marginale of soluble factors from infected calf blood mononuclear cells.
Blood mononuclear cells (lymphocytes and monocytes) were isolated from infected calves during in vivo control of acute anaplasmosis and cultured with Anaplasma marginale organisms. Supernatants from the cultures reduced the proportion of erythrocytes containing viable A. marginale in vitro, indicating that an antibody-independent mechanism of rickettsemia control might occur during acute anaplasmosis.
Department of Veterinary Microbiology and Pathology, College of Veterinary Medicine, Washington State University, Pullman 99164-7040, USA.
C R
CR
Wyatt
W C
WC
Davis
D P
DP
Knowles
W L
WL
Goff
G H
GH
Palmer
T C
TC
McGuire
D000208:Acute Disease; D000709:Anaplasma / Q000254:growth & development / Q000276:immunology*; D000712:Anaplasmosis / Q000276:immunology* / Q000382:microbiology; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology / Q000382:microbiology; D002478:Cells, Cultured; D004912:Erythrocytes / Q000382:microbiology*; D008214:Lymphocytes / Q000276:immunology*; D008297:Male; D009000:Monocytes / Q000276:immunology*