Cigarette smoking and silent brain infarction in normal adults.
We investigated the relationship between cigarette smoking and silent brain infarction in 365 neurologically normal male Japanese subjects (smokers: 119, nonsmokers: 246). Silent brain infarction was identified in 32 (26.9%) of 119 smokers and in 54 (22.8%) of 246 nonsmokers. Mild or moderate periventricular hyperintensity was presented in 27 smokers (22.7%) and 54 nonsmokers (22.8%). There was no significant difference in the regional cerebral blood flow or the average systolic, diastolic, and mean arterial blood pressures between groups. The HDL-cholesterol level was significantly lower in smokers than in nonsmokers (p < 0.01). Cigarette smoking was not related to the incidence of silent brain infarction or leuko-araiosis in healthy adults in Japan.
Third Department of Internal Medicine, Shimane Medical University.
K
K
Yamashita
S
S
Kobayashi
S
S
Yamaguchi
H
H
Koide
D002544:Cerebral Infarction / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D002560:Cerebrovascular Circulation; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects*