Investigating the effect of maternal alcohol intake on human fetal breathing rate using adaptive time-frequency analysis methods.
In this study, the matching pursuit (MP) method which is a modified version of the wavelet transform (WT) method was proposed to examine the effects of alcohol on human fetal breathing rates in both time and frequency domains. The matching pursuit method was chosen since the classical Fourier transform may not represent signals which have stationary characteristics and wavelet transform may not represent signals whose Fourier transforms have a narrow frequency support. Our results show that the horizontal structured atoms representing the sinusoidal activity at all frequency ranges disappeared and the vertical structured atoms representing the discontinuous spike type activity increased. In addition, the circular structured atoms at the high frequency range shifted to the low frequencies after the alcohol intake. The results also suggested that the matching pursuit is most suitable for analyzing the fetal breathing rate signals with and without alcohol intake.
Akay
M
M
Department of Biomedical Engineering, Rutgers University, Piscataway, NJ, USA.
Mulder
E J
EJ
D000465:Algorithms; D000431:Ethanol / Q000633:toxicity*; D005260:Female; D005333:Fetus / Q000187:drug effects* / Q000502:physiology; D005583:Fourier Analysis; D006801:Humans; D008297:Male; D011247:Pregnancy / Q000502:physiology*; D012119:Respiration / Q000187:drug effects* / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D013997:Time Factors; D016216:Ultrasonography, Prenatal
D000431:Ethanol