Changes in body weight and organ weight of Ishibashi (IS) rats with growth.
Changes in body weight (25-175 days old, every 10 days) and weights of various organs (70, 105, 140 and 175 days old), i.e., cerebrum, cerebellum, pituitary gland, thyroid gland, thymus, heart, liver, spleen, adrenal gland, kidney, seminal vesicle, prostate, epididymis, testes, bulbourethral gland and ovary, of Ishibashi (IS) rats with growth, which are model animals for congenital vertebral malformation (spontaneous kyphoscoliosis) were examined as compared with Brown Norway (BN) rats, which are genetically irrelevant to IS rats, and also with hybrid rats (IBF, rats) which are between IS and BN rats. The experimental results showed that body weight and weights of various organs except cerebrum, cerebellum and thymus were greater in IS rats than in BN rats, and body weight and weights of various organs of IBF, rats were intermediate between the two strains of rats.
Teramoto
K
K
CSK Research Park, Inc., Tokyo, Japan.
Tsuji
K
K
Saito
T
T
Kuhara
T
T
Maejima
K
K
Ishihara
T
T
Ishibashi
M
M
D000818:Animals; D001835:Body Weight / Q000502:physiology*; D001847:Bone Diseases / Q000235:genetics*; D004195:Disease Models, Animal; D005260:Female; D008159:Lumbar Vertebrae / Q000002:abnormalities*; D008297:Male; D009929:Organ Size / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains / Q000254:growth & development*; D012376:Rodent Diseases / Q000235:genetics; D012600:Scoliosis / Q000235:genetics*