Low prevalence of circulating anti-type 6 human herpes virus IgG-antibodies in Spanish children.
The prevalence of circulating anti-HHV-6 IgG-antibodies in an infant population, was investigated to assess the evolution of antibody titres from birth to adulthood. Endpoint titration was done by indirect immunofluorescence, in 525 samples of serum from children, healthy adults and pregnant women. In the children, seropositivity increased from the age of 6 months, and was highest (56.52%) between 7 months and 1 year, suggesting that the initial infection occurred between 6 and 12 months of age.
Roldan
C
C
Department of Microbiology, University of Granada, Hospital Universitario San Cecilio, Spain.
Gutiérrez
J
J
de la Higuera
A
A
Maroto
C
C
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006566:Herpesviridae Infections / Q000175:diagnosis / Q000453:epidemiology / Q000276:immunology*; D015654:Herpesvirus 6, Human / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D015995:Prevalence; D012698:Serologic Tests; D013030:Spain / Q000453:epidemiology
D000914:Antibodies, Viral; D007074:Immunoglobulin G