Unraveling mysteries associated with cat-scratch disease, bacillary angiomatosis, and related syndromes.
The search for the infectious agents responsible for cat-scratch disease, bacillary angiomatosis, and related syndromes has a long and often circuitous history. Recognition of the etiologic agents and a new understanding of the fundamental features of the epidemiology and natural history of modern day Bartonella (formerly Rochalimaea)-associated diseases culminate a multipartite story that combines clinical medicine, traditional microbiology, and novel technological approaches to solve a long-standing enigma.
Regnery
R
R
National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA. rur1@ciddvd1.em.cdc.gov
Tappero
J
J
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000209:etiology; D016917:Angiomatosis, Bacillary / Q000453:epidemiology / Q000209:etiology* / Q000635:transmission; D000818:Animals; D001431:Bacteriological Techniques; D001474:Bartonella Infections / Q000175:diagnosis / Q000209:etiology; D018416:Bartonella henselae / Q000145:classification / Q000302:isolation & purification; D002372:Cat-Scratch Disease / Q000453:epidemiology / Q000209:etiology* / Q000635:transmission; D002415:Cats; D004197:Disease Reservoirs / Q000662:veterinary; D006801:Humans; D008967:Molecular Biology