Prolonged ambulatory small intestinal and colonic motility monitoring: potential in irritable bowel syndrome--first report of prolonged ambulatory oesophageal, small intestinal and colonic motility in the same patient.
Irritable bowel syndrome (IBS), which affects up to 25% of the population in western countries and accounts for up to 50% of referrals to gastroenterologist, remains mainly a diagnosis of exclusion. We have studied, for the first time, prolonged ambulatory motility recordings from the oesophagus, small intestine and colon of a patient who was referred to us with a 12-year history of abdominal pain and a presumptive diagnosis of IBS. The results indicated that the diagnosis was pseudo-obstruction syndrome rather than IBS. Wider clinical use of the new techniques of prolonged ambulatory intestinal motility monitoring in IBS would offer considerable potential not only in achieving a greater understanding of its pathophysiology but also in providing a more precise definition of clinical and therapeutic subgroups.
Department of Gastroenterology and Nutrition, Central Middlesex Hospital NHS Trust, London, UK.
A H
AH
Raimundo
J
J
Rogers
D B
DB
Silk
D003106:Colon / Q000502:physiology; D003109:Colonic Diseases, Functional / Q000175:diagnosis*; D003937:Diagnosis, Differential; D004947:Esophagus / Q000502:physiology; D005769:Gastrointestinal Motility; D006801:Humans; D007418:Intestinal Pseudo-Obstruction / Q000175:diagnosis*; D007421:Intestine, Small / Q000502:physiology; D008297:Male; D008875:Middle Aged; D018670:Monitoring, Ambulatory