Antiepileptic drug utilization in out-patients--a prescribing pattern study.
Antiepileptic drug utilization for the treatment of different epileptic seizures had been investigated for 10 years in Bulgaria (1985-1994). The data were collected from ambulatory cards of 10,132 epileptic out-patients as well as from pharmacists' sales records. The results were expressed in DDD/1,000 inhabitants/year. During the period 1985-1989 the drug mostly prescribed had been phenobarbital both in mono- and polytherapy, but during the second period (1990-1994) it had been replaced to a high extent by carbamazepine and valproates. Polytherapy had given up its place to monotherapy in all forms of epileptic seizures during the 10-year period of investigation.
Medical University, Department of Pharmacology and Drugs Toxicology, Plovdiv, Bulgaria.
L
L
Peytchev
I
I
Atanasova
D
D
Terziivanov
D000293:Adolescent; D000328:Adult; D000368:Aged; D000927:Anticonvulsants / Q000008:administration & dosage / Q000627:therapeutic use*; D002031:Bulgaria; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D011307:Drug Prescriptions; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007223:Infant; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010045:Outpatients; D012640:Seizures / Q000188:drug therapy*; D013223:Statistics as Topic; D016896:Treatment Outcome
D000927:Anticonvulsants