Multisection T1-weighted hybrid-RARE: a pulse sequence for MR imaging of the entire liver during suspended respiration.
It is shown that the maximum average-data-collection-speed (ADCS) of multisection 2D hybrid-RARE sequences is independent of TR and TEeff, and a monotonically increasing function of echo-train-length (ETL). This result was used in the design of an optimized T1-weighted hybrid-RARE sequence that produces 20 images of the abdomen in 31 s divided into four breath-hold periods. The resulting ADCS is 58 lines in k-space per second. Twenty-four subjects (2 healthy volunteers and 22 patients) were imaged with a protocol that also included: (a) breath-hold T1-weighted FLASH which acquires data at 34 lines in k-space per second (49 s scan time), and (b) T1-weighted conventional spin-echo (9:44 minutes scan time) with respiratory compensation. The experiments show that this T1-weighted-hybrid-RARE sequence has: (1) a level of T1 weighting that is comparable with the conventional sequences, (2) very low vulnerability to susceptibility artifacts, (3) high data acquisition efficiency, and (4) higher SNR than T1-weighted-FLASH. In conclusion, the T1-weighted-hybrid-RARE sequence described herein is an efficacious and reproducible technique for rapid imaging of the upper abdomen during suspended respiration.
Boston City Hospital Center for MRI, Boston University School of Medicine, Massachusetts, USA.
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Jara
J A
JA
Soto
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Yu
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Hentzen
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van Yperen
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Yucel
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008099:Liver; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012119:Respiration; D013154:Spleen