Interleukin-6 and megakaryocytopoiesis: an update.
Interleukin-6 is a pleiotropic cytokine which shows a wide variety of biologic functions on various tissues and cells. Indeed. IL-6 acts not only B cells but also on T cells, hepatocytes, hematopoietic progenitor cells, megakaryocytes, etc. In this review, I have attempted to summarize the new data concerning the effect of IL-6 on megakaryocytes and platelets.
Laboratory of Experimental Hematology and Oncology, Catholic University of Louvain, Brussels, Belgium.
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D000740:Anemia / Q000503:physiopathology; D000818:Animals; D001792:Blood Platelets / Q000166:cytology*; D002478:Cells, Cultured; D006410:Hematopoiesis; D006412:Hematopoietic Stem Cells / Q000166:cytology*; D006801:Humans; D007249:Inflammation / Q000503:physiopathology; D015850:Interleukin-6 / Q000502:physiology*; D008533:Megakaryocytes / Q000166:cytology*; D013922:Thrombocytosis / Q000503:physiopathology
D015850:Interleukin-6