The prevention of post partum haemorrhage: optimising routine management of the third stage of labour.
This paper concerns itself with the use of oxytocic therapy as part of the routine management of the third stage of labour. It attempts to answer three different questions: (1) do oxytocics reduce the risk of post partum haemorrhage (PPH) when used during the routine management of the third stage of labour? (2) does the clinical package of active management reduce the risk of PPH (3) which is the best oxytocic to use during routine active management of the third stage? It attempts to answer these questions by presenting the evidence from formal meta-analytical reviews of the randomised controlled trials of the pertinent intervention and by presenting the results of the two trials that were undertaken as a result of the hypotheses which were generated from the formal reviews.
Royal College of Surgeons in Ireland, Academic Department OB/GYN, Coombe Women's Hospital, Dublin, Ireland.
W J
WJ
Prendiville
D001315:Australia / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007494:Ireland / Q000453:epidemiology; D007743:Labor, Obstetric / Q000187:drug effects*; D015201:Meta-Analysis as Topic; D010120:Oxytocics / Q000494:pharmacology*; D006473:Postpartum Hemorrhage / Q000453:epidemiology / Q000517:prevention & control*; D011247:Pregnancy; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D006113:United Kingdom / Q000453:epidemiology
D010120:Oxytocics