Genes for Prader Willi syndrome/Angelman syndrome and fragile X syndrome are homologous, with genetic imprinting and unstable trinucleotide repeats causing mental retardation, autism and aggression.
Genes for Prader Willi syndrome/Angelman syndrome are homologous to genes for fragile X syndrome. Genetic imprinting and expanded trinucleotide repeats cause mental retardation, autism and aggression.
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Fischer
D000374:Aggression; D017204:Angelman Syndrome / Q000235:genetics*; D000818:Animals; D001321:Autistic Disorder / Q000235:genetics*; D002874:Chromosome Mapping; D002880:Chromosomes, Human, Pair 11; D002884:Chromosomes, Human, Pair 15; D005600:Fragile X Syndrome / Q000235:genetics*; D018392:Genomic Imprinting; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics*; D008957:Models, Genetic; D011218:Prader-Willi Syndrome / Q000235:genetics*; D018911:Trinucleotide Repeats