[Comparative study on diode laser (680 nm) and krypton laser mild photocoagulation--histological findings and therapeutic outcome for diabetic maculopathy].
A histopathological study of macaca monkey retina-choroid was carried out for one month after mild photocoagulation with a diode laser (680 nm) and a krypton laser (647 nm). Both lasers produced the same damage to the outer layer of retina and to the melanocytes of 1/3 of the inner choroid. Mild focal photocoagulation was done for 6 patients (12 eyes) with diabetic maculopathy. The patients were 41 to 67 years old, suffering from diabetes mellitus for 5 to 25 years. The grade of their retinopathy was Fukuda's classification AI, AII, and BI. AII eyes were tested before and 3-6 months after photocoagulation for corrected visual acuity, fluorescein angiography, and visual field sensitivity by Octopus automated static perimetry. Visual acuity was stable in all cases. Central sensitivity was better in 2 eyes and unchanged in 4 eyes in both types of laser photocoagulation. In cases of total loss, one eye was improved, 4 eyes were unchanged and one eye was worsened by diode laser photocoagulation and one eye was improved, 2 eyes were unchanged and 3 eyes were worsened by krypton laser photocoagulation. The diode laser (680 nm) might be as useful for ophthalmic laser treatment as the krypton laser.
Okuyama
M
M
Department of Ophthalmology, National Defense Medical College, Saitama-ken, Japan.
Okisaka
S
S
Nakagami
T
T
Sai
Y
Y
Mizukawa
A
A
Ito
M
M
Ohta
Y
Y
D000328:Adult; D000368:Aged; D000818:Animals; D002829:Choroid / Q000473:pathology; D003930:Diabetic Retinopathy / Q000601:surgery*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D017075:Laser Coagulation / Q000379:methods*; D008251:Macaca; D008266:Macula Lutea; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000473:pathology*; D016896:Treatment Outcome; D014792:Visual Acuity