Identification of numerous hepatitis C virus genotypes in Montreal, Canada.
Hepatitis C virus genotypes were determined for 358 viremic individuals in Montreal, Canada, by restriction endonuclease analysis of PCR products and phylogenetic analysis of core gene sequences. Types 1, 2, and 3 occurred in 62.8, 14.2, and 13.7%, respectively; types 4 and 5 were found in 3.9 and 4.5%, respectively; and genotypes 6a and 7c and a novel genotype each occurred in 0.3%. Types 4, 6, and 7 and the novel genotype were mostly from persons who had immigrated to Canada.
Département de Microbiologie et Immunologie, Université de Montréal, Québec, Canada.
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L
Bernier
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B
Willems
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G
Delage
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Murphy
D000328:Adult; D004641:Emigration and Immigration; D005838:Genotype; D016174:Hepacivirus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D006526:Hepatitis C / Q000453:epidemiology / Q000821:virology; D006801:Humans; D008875:Middle Aged; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D011792:Quebec / Q000453:epidemiology; D012367:RNA, Viral / Q000235:genetics; D014766:Viremia / Q000821:virology
D012367:RNA, Viral