Is the ratio of inhaled corticosteroid to bronchodilator a good indicator of the quality of asthma prescribing? Cross sectional study linking prescribing data to data on admissions.
OBJECTIVE
To investigate the ratio of inhaled corticosteroid to bronchodilator as a measure of the quality of asthma prescribing by general practitioners.


METHODS
Ecological cross sectional study linking general practitioner asthma prescribing with hospital admission data and a measure of deprivation.


METHODS
11 family health services authorities in the West Midlands region and 99 general practices in North Staffordshire.


METHODS
Hospital admission rates for asthma; the ratio of inhaled corticosteroid to bronchodilator; and Townsend deprivation scores.


RESULTS
No overall significant correlation was found between admission rates for asthma and corticosteroid:bronchodilator ratios for family health services authorities (Spearman's rs = -0.109, P = 0.750) or general practices (rs = -0.084, P = 0.407). In deprived family health services authority areas and general practices an inverse non-significant correlation existed between admission rates for asthma and corticosteroid:bronchodilator ratios (rs = -0.300, P = 0.624; rs = -0.218, P = 0.136). In contrast, in more affluent areas and general practices a positive non-significant correlation existed between admission rates and corticosteroid:bronchodilator ratios (rs = 0.371, P = 0.468; rs = 0.038, P = 0.792).


CONCLUSIONS
Although the corticosteroid:bronchodilator ratio may be a valid indicator of the quality of prescribing for individual patients with asthma, caution should be applied in interpreting aggregated ratios. Differences in the severity of asthma or the prevalence of chronic obstructive pulmonary disease may explain inconsistent associations between admission rates for asthma and corticosteroid:bronchodilator ratios in family health services authorities and general practices with different deprivation scores.
Shelley
M
M
Industrial and Community Health Research Centre, School of Postgraduate Medicine, Keele University, North Staffordshire Medical Institute, Stoke on Trent.
Croft
P
P
Chapman
S
S
Pantin
C
C
D000280:Administration, Inhalation; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D001249:Asthma / Q000188:drug therapy* / Q000453:epidemiology; D001993:Bronchodilator Agents / Q000008:administration & dosage*; D003430:Cross-Sectional Studies; D004739:England / Q000453:epidemiology; D005194:Family Practice / Q000592:standards*; D006801:Humans; D010343:Patient Admission; D010818:Practice Patterns, Physicians' / Q000592:standards*; D012959:Socioeconomic Factors
D000305:Adrenal Cortex Hormones; D001993:Bronchodilator Agents