Difficulties in excluding the diagnosis of retinoblastoma in cases of advanced Coats' disease: a clinicopathologic report.
We highlight the difficulty in differentiating Coats' disease from retinoblastoma. Two patients with bullous exudative retinal detachment and abnormal vessels are discussed. Histologic evaluation of the 5-year-old patient revealed retinoblastoma. The 1-year-old patient had Coats' disease by histologic identification. With this in mind, we suggest enucleation of such eyes if diagnostic uncertainty exists, since failure to treat retinoblastoma is a more serious error than enucleation of an eye with minimal function.
Schepens Retina Associates, Schepens Eye Research Institute, Boston, MA 02114, USA.
S M
SM
Steidl
T
T
Hirose
D
D
Sang
M E
ME
Hartnett
D002114:Calcinosis / Q000000981:diagnostic imaging; D002675:Child, Preschool; D003937:Diagnosis, Differential; D015353:Eye Enucleation; D005134:Eye Neoplasms / Q000175:diagnosis*; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D007223:Infant; D012163:Retinal Detachment / Q000473:pathology; D012164:Retinal Diseases / Q000175:diagnosis*; D012171:Retinal Vessels / Q000473:pathology; D012175:Retinoblastoma / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography