Biodistribution of the lipophilic complexes 59Fe(RsalH2)3tach (R = H, NO2 and OMe) and 68Ga(NO2salH2)3tach.
A series of highly lipophilic comploffs 59Fe(RsalH2)3tach (R = H, NO2, OMe) and 68Ga(NO2salH2)3tach have been evaluated in vivo as potentially clinically useful agents.
Bollinger
J E
JE
Department of Chemistry, Tulane University, New Orleans, LA 70118, USA.
Banks
W A
WA
Kastin
A J
AJ
Welch
M J
MJ
Roundhill
D M
DM
D000818:Animals; D001596:Benzylamines / Q000138:chemical synthesis / Q000493:pharmacokinetics*; D003514:Cyclohexylamines / Q000138:chemical synthesis / Q000493:pharmacokinetics*; D004355:Drug Stability; D005710:Gallium Radioisotopes / Q000493:pharmacokinetics*; D007504:Iron Radioisotopes / Q000493:pharmacokinetics*; D007668:Kidney / Q000000981:diagnostic imaging / Q000378:metabolism; D007700:Kinetics; D008099:Liver / Q000000981:diagnostic imaging / Q000378:metabolism; D008297:Male; D051379:Mice; D011877:Radionuclide Imaging; D013053:Spectrophotometry; D014018:Tissue Distribution
D001596:Benzylamines; D003514:Cyclohexylamines; D005710:Gallium Radioisotopes; D007504:Iron Radioisotopes