[Comparative study on diode laser (680 nm) and krypton laser mild photocoagulation--histological findings and therapeutic outcome for diabetic maculopathy].
A histopathological study of macaca monkey retina-choroid was carried out for one month after mild photocoagulation with a diode laser (680 nm) and a krypton laser (647 nm). Both lasers produced the same damage to the outer layer of retina and to the melanocytes of 1/3 of the inner choroid. Mild focal photocoagulation was done for 6 patients (12 eyes) with diabetic maculopathy. The patients were 41 to 67 years old, suffering from diabetes mellitus for 5 to 25 years. The grade of their retinopathy was Fukuda's classification AI, AII, and BI. AII eyes were tested before and 3-6 months after photocoagulation for corrected visual acuity, fluorescein angiography, and visual field sensitivity by Octopus automated static perimetry. Visual acuity was stable in all cases. Central sensitivity was better in 2 eyes and unchanged in 4 eyes in both types of laser photocoagulation. In cases of total loss, one eye was improved, 4 eyes were unchanged and one eye was worsened by diode laser photocoagulation and one eye was improved, 2 eyes were unchanged and 3 eyes were worsened by krypton laser photocoagulation. The diode laser (680 nm) might be as useful for ophthalmic laser treatment as the krypton laser.
Department of Ophthalmology, National Defense Medical College, Saitama-ken, Japan.
M
M
Okuyama
S
S
Okisaka
T
T
Nakagami
Y
Y
Sai
A
A
Mizukawa
M
M
Ito
Y
Y
Ohta
D000328:Adult; D000368:Aged; D000818:Animals; D002829:Choroid / Q000473:pathology; D003930:Diabetic Retinopathy / Q000601:surgery*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D017075:Laser Coagulation / Q000379:methods*; D008251:Macaca; D008266:Macula Lutea; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000473:pathology*; D016896:Treatment Outcome; D014792:Visual Acuity