Magnesium taurate for the prevention and treatment of pre-eclampsia/eclampsia.
The use of parenteral magnesium sulfate for the management of pre-eclampsia/eclampsia is well established. In striking analogy to the effects of hypermagnesemia, taurine has antivasospastic, antihypertensive, platelet-stabilizing, anticonvulsant and hypoxia-protective properties. Thus parenteral magnesium taurate can reasonably be proposed as a superior alternative to magnesium sulfate in the treatment of pre-eclampsia; administered orally as a component of prenatal supplementation, magnesium taurate might well have both preventive and therapeutic value in this syndrome. In the light of the hypoxia-protective actions of both magnesium and taurine, such supplementation might also protect fetuses experiencing temporary perinatal asphyxia, lessening the risk of cerebral palsy.
Nutrition 21, San Diego, CA 92109, USA.
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McCarty
D004461:Eclampsia / Q000188:drug therapy* / Q000517:prevention & control*; D005260:Female; D005333:Fetus; D005527:Food, Fortified; D006801:Humans; D008274:Magnesium / Q000627:therapeutic use; D008962:Models, Theoretical; D011225:Pre-Eclampsia / Q000188:drug therapy* / Q000517:prevention & control*; D011247:Pregnancy; D013654:Taurine / Q000008:administration & dosage / Q000627:therapeutic use
D013654:Taurine; D008274:Magnesium