Congenital insensitivity to pain: orthopaedic implications.
We report two children in one family with congenital insensitivity to pain, anhidrosis, and mental retardation with behavioural disturbance. Orthopaedic manifestations of this condition include recurrent fractures, osteomyelitis, and neuropathic joints. The differential diagnoses and difficulties in the management of this rare disorder are discussed.
Princess Margaret Rose Orthopaedic Hospital, Edinburgh, Scotland.
R S
RS
Kuo
M F
MF
Macnicol
D002648:Child; D050723:Fractures, Bone / Q000150:complications*; D006801:Humans; D007007:Hypohidrosis / Q000150:complications; D008607:Intellectual Disability / Q000150:complications; D007592:Joint Diseases / Q000150:complications; D008297:Male; D010019:Osteomyelitis / Q000150:complications; D000699:Pain Insensitivity, Congenital / Q000150:complications* / Q000235:genetics; D011379:Prognosis; D012008:Recurrence