Morphometric development of the human fetal auditory system: inferior collicular nucleus.
The development of the human inferior collicular nucleus was studied on serial sections of the brains of 9 fetuses at 12-34 weeks of gestation and an adult of 63 years using an electronic planimeter with a computer. Morphometric analysis of the development of the inferior collicular nucleus showed that its development accelerates after 18 weeks of gestation in terms of the columnar volume and length, size of neurons and circularity ratio. Large-sized neurons 2-3 times the area of small-sized neurons appeared after 18 weeks of gestation. The ratio of large neurons to the total ranged between 3 and 6% in the inferior collicular nucleus. The development of the inferior collicular nucleus was similar to that of the ventral cochlear nucleus and the medial superior olivary nucleus.
Division of Neurology, Saitama Children's Medical Center, Japan.
T
T
Nara
N
N
Goto
S
S
Hamano
A
A
Okada
D000367:Age Factors; D001306:Auditory Pathways; D002452:Cell Count; D048429:Cell Size; D005333:Fetus / Q000166:cytology* / Q000196:embryology; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000254:growth & development; D007245:Inferior Colliculi / Q000166:cytology* / Q000196:embryology / Q000254:growth & development; D008875:Middle Aged; D009474:Neurons / Q000166:cytology