Autoimmune hemolytic anemia in multicentric Castleman's disease.
We report on a patient affected by multicentric Castleman's disease who developed an acute immunohemolytic anemia due to warm antibody. The clinical course was characterized by refractoriness to the steroidal treatment and by a dramatic improvement of the hematological and objective picture following combination chemotherapy (CHOP regimen). The possible existence of a link between the lymphoproliferative syndrome and the immunological derangement is also discussed.
Divisione di Medicina, Ospedale C. Mira, Casorate Primo, Italy.
N L
NL
Liberato
P
P
Bollati
F
F
Chiofalo
M
M
Filipponi
M
M
Poli
D000208:Acute Disease; D000368:Aged; D000744:Anemia, Hemolytic, Autoimmune / Q000276:immunology*; D005871:Castleman Disease / Q000276:immunology*; D006801:Humans; D007518:Isoantibodies / Q000097:blood; D008297:Male
D007518:Isoantibodies