Influence of growth selection in turkeys on resistance to Pasteurella multocida.
Four lines of turkeys, a randombred control (RBC2) started in 1966 and three sire lines (F, A, and B), were challenged with a field isolate of Pasteurella multocida (capsular serogroup A, somatic serotype 3, 4) at 6 wk of age. Line F, a subline of the RBC2 line, was selected for 28 generations for increased 16-wk BW and Lines A and B were primary breeding sire lines from two commercial breeders. Each bird was inoculated subcutaneously in the back of the neck with 1.2 x 10(7) washed bacteria. Mortality following challenge with P. multocida was higher in the sire lines (54 to 65%) than in the RBC2 line (26%). There was no significant difference in mortality among sire lines following challenge. These results suggest that the increased susceptibility to P. multocida in the F line in comparison to its control may be due to genetic changes resulting from selection for increased BW in this line.
Nestor
K E
KE
Department of Animal Sciences, Ohio Agricultural Research and Development Center, Ohio State University, Wooster 44691, USA.
Saif
Y M
YM
Zhu
J
J
Noble
D O
DO
D000375:Aging / Q000276:immunology; D000818:Animals; D000907:Antibodies, Bacterial / Q000276:immunology / Q000378:metabolism; D001947:Breeding; D005260:Female; D007113:Immunity, Innate / Q000235:genetics*; D008297:Male; D010326:Pasteurella Infections / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary*; D016979:Pasteurella multocida / Q000276:immunology*; D011201:Poultry Diseases / Q000276:immunology / Q000401:mortality / Q000517:prevention & control*; D012641:Selection, Genetic; D014422:Turkeys / Q000235:genetics / Q000254:growth & development / Q000276:immunology*
D000907:Antibodies, Bacterial