Fatal familial insomnia: a seventh family.
A 60-year-old woman with a typical history of fatal familial insomnia (FFI) had FFI proven by histologic examination and molecular testing. Her son, who died at the age of 20 in 1978, had a rapidly progressive dementing illness without reported insomnia. He carried the characteristic mutation for FFI and is the youngest patient reported with this condition.
Princess Alexandra Hospital, Brisbane, Australia.
P
P
Silburn
L
L
Cervenáková
P
P
Varghese
A
A
Tannenberg
P
P
Brown
R
R
Boyle
D000328:Adult; D005260:Female; D006801:Humans; D008875:Middle Aged; D017096:Prion Diseases / Q000473:pathology*; D013788:Thalamus / Q000473:pathology