Accidental self inoculation with oil based veterinary vaccines.
OBJECTIVE
To report the adverse local effects of inadvertent self inoculation with oil-based veterinary vaccines.


METHODS
Three case reports and a literature review.


RESULTS
One patient developed extensive chronic granulomatous inflammation in the thigh following intramuscular injection of Footvax vaccine requiring major surgical debridements. The other two cases developed chronic inflammation and sterile abscess formation following subcutaneous injections in the hand, requiring surgical drainage and corticosteroids to eventually heal.


CONCLUSIONS
The mineral oil used as an adjuvant in veterinary vaccines can cause a prolonged chronic granulomatous reaction with sterile abscess formation. Surgical debridement may be required to remove the oil to prevent chronic sequelae. Oral corticosteroids should be considered once infection has been excluded.
Department of Orthopaedic Surgery, Dunedin Hospital.
D P
DP
Jones
D000328:Adult; D006801:Humans; D008297:Male; D008875:Middle Aged; D008899:Mineral Oil / Q000009:adverse effects; D016602:Needlestick Injuries / Q000150:complications / Q000628:therapy; D009784:Occupational Diseases / Q000209:etiology / Q000628:therapy; D014612:Vaccines / Q000009:adverse effects; D014730:Veterinary Medicine
D014612:Vaccines; D008899:Mineral Oil