[How should mentally handicapped adults with depressive disorders be treated psychopharmacologically?].
The psychotropic drug treatment being administrated to 38 mentally retarded persons (age > 19 years) with current DSM-III-R depressive disorders and living in different types of residential care institutions was compared with that received by a non-depressive group of mental retarded adults (n = 146). The individuals with depressive disorders more frequently received treatment with at least one psychotropic drug (45% vs 22%), most often neuroleptics (45% vs 18%) and seldom antidepressants (11% vs 0%). These results suggest that treatment is frequently inappropriate and ineffective.
Albertinen-Haus, Medizinisch-Geriatrische Klinik, Hamburg.
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D000328:Adult; D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use; D015897:Comorbidity; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D004359:Drug Therapy, Combination; D004363:Drug Utilization; D005260:Female; D005858:Germany; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy* / Q000523:psychology; D008297:Male; D008875:Middle Aged; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000627:therapeutic use*; D012112:Residential Facilities
D000928:Antidepressive Agents; D014150:Antipsychotic Agents; D011619:Psychotropic Drugs