Muscle glycogen recovery after exercise during glucose and fructose intake monitored by 13C-NMR.
The purpose of this study was to examine muscle glycogen recovery with glucose feeding (GF) compared with fructose feeding (FF) during the first 8 h after partial glycogen depletion using 13C-nuclear magnetic resonance (NMR) on a clinical 1.5-TNMR system. After measurement of the glycogen concentration of the vastus lateralis (VL) muscle in seven male subjects, glycogen stores of the VL were depleted by bicycle exercise. During 8 h after completion of exercise, subjects were orally given either GF or FF while the glycogen content of the VL was monitored by 13C-NMR spectroscopy every second hour. The muscular glycogen concentration was expressed as percentage of the glycogen concentration measured before exercise. The glycogen recovery rate during GF (4.2 +/- 0.2%/h) was significantly higher (P < 0.05) compared with values during FF (2.2 +/- 0.3%/h). This study shows that 1) muscle glycogen levels are perceptible by 13 C-NMR spectroscopy at 1.5 T and 2) the glycogen restoration rate is higher after GF compared with after FF.
Department of Radiology, University of Nijmegen, The Netherlands.
A J
AJ
Van Den Bergh
S
S
Houtman
A
A
Heerschap
N J
NJ
Rehrer
H J
HJ
Van Den Boogert
B
B
Oeseburg
M T
MT
Hopman
D000328:Adult; D015444:Exercise / Q000502:physiology*; D005632:Fructose / Q000494:pharmacology*; D005947:Glucose / Q000494:pharmacology*; D006003:Glycogen / Q000378:metabolism*; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D018482:Muscle, Skeletal / Q000187:drug effects / Q000378:metabolism*
D005632:Fructose; D006003:Glycogen; D005947:Glucose