Can Ca2+ be released from secretory granules or synaptic vesicles?
Recent studies on single isolated secretory granules, as well as secretory granules in intact cells, show that Ca2+ is released from the granule store into the cytosol via a messenger-mediated pathway following agonist binding. This is important for generation of localized cytosolic Ca2+ signals which can initiate exocytosis.
Petersen
O H
OH
Dept of Physiology, University of Liverpool, UK.
D002118:Calcium / Q000378:metabolism*; D003594:Cytoplasmic Granules / Q000737:chemistry / Q000378:metabolism*; D013572:Synaptic Vesicles / Q000737:chemistry / Q000378:metabolism*
D002118:Calcium