Chondrosarcomatous cutaneous metastasis. A unique manifestation of sarcomatoid (metaplastic) breast carcinoma.
Breast carcinoma is the most common origin of cutaneous metastasis in women but is usually of ductal or lobular histotypes. Sarcomatoid (metaplastic) carcinoma of the breast, although a well-established aggressive neoplasm, is very uncommon. The metaplastic elements span all types of mesenchymal differentiation and have been demonstrated to be derived from carcinomatous elements. Skin metastasis from such lesions is extremely rare. A case of metastatic sarcomatoid breast carcinoma to the skin is described in which the histology of the metastases was that of chondrosarcoma.
Department of Pathology, Bowman Gray School of Medicine/North Carolina Baptist Hospital, Winston-Salem 27157, USA.
C W
CW
Sexton
W L
WL
White
D000368:Aged; D001943:Breast Neoplasms; D005260:Female; D006801:Humans; D008679:Metaplasia; D012509:Sarcoma / Q000473:pathology* / Q000556:secondary*; D012878:Skin Neoplasms / Q000473:pathology* / Q000556:secondary*