Pulmonary fibrosis in a carpenter with long-lasting exposure to fiberglass.
A 56-year-old male carpenter had a history of glass fiber inhalation for 41 years without any protective device. His chest radiograph showed small nodular opacities in lower lung fields and multiple cystic lesions and low attenuation areas in upper lung fields. Light and polarizing microscopic examinations of his transbronchial lung biopsy specimen revealed mild interstitial fibrosis and mononuclear cell infiltration in alveolar walls without birefringent substances. However, widespread depositions of small glass fibers (< 2.5 microns in length and 0.3 micron in diameter) were detected by analytical electron microscopy, which suggested their possible contribution to the development of his pulmonary fibrosis.
First Department of Medicine School of Medicine, Hokkaido University, Sapporo, Japan.
T
T
Takahashi
M
M
Munakata
H
H
Takekawa
Y
Y
Homma
Y
Y
Kawakami
D005898:Glass; D006801:Humans; D008297:Male; D008875:Middle Aged; D019016:Mineral Fibers / Q000009:adverse effects*; D009784:Occupational Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D014057:Tomography, X-Ray Computed
D019016:Mineral Fibers; C009753:fiberglass