Methods of measuring susceptibility of anaerobic bacteria to trovafloxacin, including quality control parameters.
Three methods approved by the National Committee for Clinical Laboratory Standards for testing the susceptibility of anaerobic bacteria were used to evaluate the fluoroquinolone, trovafloxacin. The methods gave essentially comparable results with 126 anaerobes and with three quality control strains. A collaborative study defined the quality control range for trovafloxacin MICs. Trovafloxacin had good in vitro activity against the more common anaerobes (MIC 90 < = or 2.0 micrograms/ml).
Barry
A L
AL
Clinical Microbiology Institute, Tualatin, Oregon 97062, USA.
Fuchs
P C
PC
Thornsberry
C
C
McLaughlin
J C
JC
Jenkins
S G
SG
Hardy
D J
DJ
Allen
S D
SD
D000890:Anti-Infective Agents / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D024841:Fluoroquinolones; D008826:Microbial Sensitivity Tests; D009287:Naphthyridines / Q000494:pharmacology*; D011786:Quality Control
D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D009287:Naphthyridines; C080163:trovafloxacin