Increased QT dispersion and cardiac adrenergic dysinnervation in diabetic patients with autonomic neuropathy.
Diabetic patients with autonomic neuropathy showed an increase in QTc dispersion correlated with cardiac adrenergic dysinnervation. A larger prospective study in a diabetic population is needed to assess whether QT dispersion increases the risk of arrhythmogenicity through autonomic dysfunction.
Second Department of Internal Medicine Faculty of Medicine, University of The Ryukyus, Nishihara, Okinawa, Japan.
M
M
Shimabukuro
T
T
Chibana
H
H
Yoshida
F
F
Nagamine
I
I
Komiya
N
N
Takasu
D000320:Adrenergic Fibers; D000368:Aged; D016022:Case-Control Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000503:physiopathology*; D003929:Diabetic Neuropathies / Q000000981:diagnostic imaging / Q000209:etiology / Q000503:physiopathology*; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging / Q000294:innervation* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015899:Tomography, Emission-Computed, Single-Photon