Geographic clustering of human Y-chromosome haplotypes.
Five polymorphic markers on the Y-chromosome (mostly microsatellites) were typed in 121 individuals from 13 populations around the world. With these markers 78 different haplotypes were detected. Haplotypes present more than once tend to be shared by individuals from the same population or continent. A reconstruction of haplotype phylogeny also indicates significant geographic structure in the data. Based on the similarity of the haplotypes, population relationships were examined and found to be largely concordant with those obtained with other markers. Even though the sample size and the number of markers are small, there is very signficant clustering of the haplotypes by continent of origin.
Ruiz Linares
A
A
Department of Genetics, Stanford University, CA 94305, USA.
Nayar
K
K
Goldstein
D B
DB
Hebert
J M
JM
Seielstad
M T
MT
Underhill
P A
PA
Lin
A A
AA
Feldman
M W
MW
Cavalli Sforza
L L
LL
D000483:Alleles; D016000:Cluster Analysis; D005819:Genetic Markers; D006239:Haplotypes; D006801:Humans; D018895:Microsatellite Repeats; D044468:Native Hawaiian or Pacific Islander / Q000235:genetics*; D010802:Phylogeny; D011110:Polymorphism, Genetic; D044469:Racial Groups; D014998:Y Chromosome / Q000235:genetics*
D005819:Genetic Markers