Staphylococcus aureus vaccination for dialysis patients--an update.
Staphylococcus aureus infections are a major cause in both hemodialysis and peritoneal dialysis patients. The availability of a safe and effective protective vaccine would be of great benefit to these patients, but attempts at using vaccines consisting of inactivated whole cells have been unsuccessful. This article discusses an alternate approach to S. aureus vaccine design using a capsular polysaccharide conjugate and preliminary results in hemodialysis and peritoneal patients.
W.W. Karakawa Microbial Pathogenesis Laboratory, NABI, Rockville, MD 20852, USA.
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D000818:Animals; D001428:Bacterial Vaccines; D006801:Humans; D007676:Kidney Failure, Chronic / Q000276:immunology; D017582:Renal Replacement Therapy; D013203:Staphylococcal Infections / Q000517:prevention & control*; D013211:Staphylococcus aureus; D014611:Vaccination
D001428:Bacterial Vaccines