[Comparison of analgesic effect of lidocaine tape versus eutectic mixture of lidocaine and tetracaine during infiltration of local anesthetics before epidural block].
We compared analgesic effects of a lidocaine tape (Penles) and the eutectic mixture of lidocaine and tetracaine (LT ointment) during local infiltration before epidural block. Ninety-six patients were randomly assigned to 3 groups. In groups 1 and 2, lidocaine tape was applied on the skin of the epidural puncture site 30-60 min before epidural block. In group 3, 1 g of LT ointment was applied on the same place 1-2 h before block. Additionally, patients in groups 2 and 3 were medicated intramuscularly with midazolam 5 mg. Although no significant difference in pain relief in 5 pin prick tests was observed among the three groups, there was a significantly greater decrease in the pain score during the infiltration of local anesthetics in groups 1 and 2, compared with group 3. There was no significant difference in the pain score between groups 1 and 2. We concluded that lidocaine tape is more useful than LT ointment in decreasing pain of local infiltration anesthesia, and midazolam did not exert any supplementary analgesic effect.
Kawano
T
T
Department of Anesthesia, Kawanishi City Hospital.
Shiraishi
S
S
Nakamura
T
T
Yokoo
H
H
Takasaki
M
M
D000287:Administration, Topical; D000328:Adult; D000767:Anesthesia, Epidural; D000772:Anesthesia, Local / Q000009:adverse effects*; D019162:Anesthetics, Combined; D000779:Anesthetics, Local; D014151:Anti-Anxiety Agents; D004304:Dosage Forms; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008012:Lidocaine; D008297:Male; D008874:Midazolam; D008875:Middle Aged; D010146:Pain / Q000209:etiology* / Q000517:prevention & control*; D011229:Preanesthetic Medication; D013129:Spinal Puncture / Q000009:adverse effects; D013748:Tetracaine
D019162:Anesthetics, Combined; D000779:Anesthetics, Local; D014151:Anti-Anxiety Agents; D004304:Dosage Forms; D013748:Tetracaine; D008012:Lidocaine; D008874:Midazolam