Characterization of debris adjacent to failed knee implants of 3 different designs.
Wear debris particles have been associated with bone resorption and loosening of total joint implants. To characterize the wear particles around failed knee prostheses, tissues adjacent to 47 implants of 3 different designs were evaluated: 29 were posterior cruciate ligament retention type (Group I), 12 were posterior cruciate ligament sacrificing or substituting (Total Condylar, Insall-Burstein), (Group II), and 6 were mobile bearing (posterior cruciate ligament retaining LCS), (Group III). Wear particles were isolated and evaluated using electronic particle quantitation and scanning electron microscopy. The corresponding implants were also evaluated, and the surface damage quantified. The number of particles smaller than 10 microm ranged from 8.9 to 45.8 x 10(9) per gram of tissue (dry weight). Particle number directly correlated with duration of implantation. Group I implants had larger particles, and showed greater surface damage than the other 2 designs. Polyethylene surface damage significantly correlated with particle size more than 10 microm in length. Particle number showed a significant inverse correlation with the thickness of the polyethylene. These results support previous mechanical and retrieval studies suggesting that increased wear may be associated with thinner polyethylene, and there are differing degrees and patterns of wear based on implant design.
Hirakawa
K
K
The Cleveland Clinic Foundation, OH, USA.
Bauer
T W
TW
Stulberg
B N
BN
Wilde
A H
AH
Borden
L S
LS
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003343:Corrosion; D005549:Foreign-Body Reaction / Q000209:etiology*; D006801:Humans; D007720:Knee Prosthesis / Q000009:adverse effects* / Q000379:methods; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D010316:Particle Size; D011095:Polyethylenes / Q000009:adverse effects*; D011474:Prosthesis Design; D011475:Prosthesis Failure
D011095:Polyethylenes