Design and synthesis of a series of non-peptide high-affinity human corticotropin-releasing factor1 receptor antagonists.
Neurocrine Biosciences, San Diego, California 92121, USA.
C
C
Chen
R
R
Dagnino
E B
EB
De Souza
D E
DE
Grigoriadis
C Q
CQ
Huang
K I
KI
Kim
Z
Z
Liu
T
T
Moran
T R
TR
Webb
J P
JP
Whitten
Y F
YF
Xie
J R
JR
McCarthy
D000814:Aniline Compounds / Q000737:chemistry*; D003346:Corticotropin-Releasing Hormone / Q000378:metabolism; D000242:Cyclic AMP / Q000378:metabolism; D004339:Drug Compounding / Q000379:methods*; D015195:Drug Design; D006801:Humans; D007700:Kinetics; D011743:Pyrimidines / Q000737:chemistry*; D018019:Receptors, Corticotropin-Releasing Hormone / Q000037:antagonists & inhibitors* / Q000378:metabolism; D000099052:CRF Receptor, Type 1
D000814:Aniline Compounds; D011743:Pyrimidines; D018019:Receptors, Corticotropin-Releasing Hormone; D000099052:CRF Receptor, Type 1; D003346:Corticotropin-Releasing Hormone; D000242:Cyclic AMP