Isolation and mapping of the human glycoprotein M6 gene (GPM6A) to 4q33-->q34.
We have isolated a human cDNA that is highly homologous to the murine gene (Gpm6) encoding a membrane glycoprotein, M6. The human gene (GPM6A) contains an open reading frame of 834 nucleotides encoding a peptide of 278 amino acids. Northern-blot analysis revealed specific expression in human brain. We assigned the GPM6A locus to chromosome bands 4q33-->q34 by radiation hybrid mapping.
Otsuka GEN Research Institute, Otsuka Pharmaceutical Co., Ltd., Tokushima, Japan. Shimizu@otsuka.genome.ad.jp
F
F
Shimizu
T K
TK
Watanabe
T
T
Fujiwara
E
E
Takahashi
Y
Y
Nakamura
H
H
Maekawa
D000595:Amino Acid Sequence; D001483:Base Sequence; D015152:Blotting, Northern; D002871:Chromosome Banding; D002874:Chromosome Mapping; D002894:Chromosomes, Human, Pair 4; D006801:Humans; D008562:Membrane Glycoproteins / Q000235:genetics*; D008969:Molecular Sequence Data; D009419:Nerve Tissue Proteins / Q000235:genetics*; D012333:RNA, Messenger / Q000032:analysis
C484158:GPM6A protein, human; D008562:Membrane Glycoproteins; D009419:Nerve Tissue Proteins; D012333:RNA, Messenger