Notes on the cell biology of tissue factor.
Tissue factor is both a trigger of blood coagulation and a true receptor inducing an intracellular signal upon binding of its ligand factor VII to its extracellular parts. When induced in endothelial cells more than 75% of tissue factor antigen was found on the apical side of the cell.
Biotechnology Centre of Oslo, University of Oslo, Norway.
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D000818:Animals; D000954:Antigens, Surface / Q000097:blood; D002118:Calcium / Q000502:physiology; D002460:Cell Line; D004285:Dogs; D004730:Endothelium, Vascular / Q000166:cytology / Q000378:metabolism*; D000882:Haplorhini; D006801:Humans; D015398:Signal Transduction / Q000502:physiology; D013925:Thromboplastin / Q000096:biosynthesis / Q000276:immunology / Q000502:physiology*
D000954:Antigens, Surface; D013925:Thromboplastin; D002118:Calcium