Diffuse testicular microlithiasis associated with intratubular germ cell neoplasia and seminoma.
Testicular microlithiasis is an uncommon condition in which multiple calcifications develop in the seminiferous tubules. Sonography demonstrates a typical pattern of diffuse, hyperechoic specks. This condition has been associated with premalignant and malignant changes of the testicle. We present a case of intratubular germ cell neoplasia and a microscopic focus of seminoma found in a patient with isolated testicular microlithiasis and no focal mass. Physicians should be more aware of testicular microlithiasis, and heightened surveillance is recommended to identify progression to tumor formation.
Kaveggia
F F
FF
Department of Urology, Mercy Hospital, Janesville, Wisconsin, USA.
Strassman
M J
MJ
Apfelbach
G L
GL
Hatch
J L
JL
Wirtanen
G W
GW
D000328:Adult; D002137:Calculi / Q000150:complications* / Q000473:pathology; D018237:Germinoma / Q000150:complications*; D006801:Humans; D008297:Male; D018239:Seminoma / Q000150:complications*; D013733:Testicular Diseases / Q000150:complications* / Q000473:pathology; D013736:Testicular Neoplasms / Q000150:complications*