Improvement following correction of secondary mitral regurgitation in end-stage cardiomyopathy with mitral annuloplasty.
Twenty consecutive patients with severe mitral regurgitation secondary to end-stage dilated cardiomyopathy underwent mitral annuloplasty for refractory symptoms of heart failure. On follow-up 18 +/- 4 months after annuloplasty, 14 patients (70%) were alive, all 14 noted symptomatic improvement, and quantitative echocardiographic/Doppler demonstrated decreases in left ventricular volume and sphericity accompanied by increases in ejection fraction and forward cardiac output.
Department of Internal Medicine, University of Michigan, Ann Arbor 48109, USA.
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D002311:Cardiomyopathy, Dilated / Q000150:complications*; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D016277:Ventricular Function, Left