Usefulness and problems of stereotactic radiosurgery using a linear accelerator.
Since the introduction of linac radiosurgery in October 1994, we have treated 27 patients with 36 lesions. We treated nine AVM, 12 metastatic brain tumors, two malignant lymphomas, one anaplastic astrocytoma, two meningiomas, and one brain tumor of unknown pathology. In the follow-up examinations at least five months after treatment, the local control rate was 83% for the metastatic tumors, and two malignant lymphomas disappeared completely. In addition, satisfactory results have been obtained with AVM and other brain tumors without any side effects. In comparison with gamma-knife radiosurgery, linac radiosurgery has some disadvantages such as longer treatment time and cumbersome accuracy control, but if accuracy control is performed periodically, accuracies of 1 mm or less can be obtained. There is some strengths of linac radiosurgery as follow. 1) The acquisition cost is relatively low. 2) Dose distribution are equivalent to gamma-knife. 3) There is no field size limitation. 4) There is great flexibility in beam delivery and linac systems. Radiosurgery using linear accelerators seems to become widely accepted in the future.
Department of Radiology, Juntendo University, Tokyo, Japan.
Y
Y
Naoi
N
N
Cho
T
T
Miyauchi
Y
Y
Iizuka
T
T
Maehara
H
H
Katayama
D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis / Q000601:surgery*; D019786:Gadolinium DTPA; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D009942:Organometallic Compounds; D010315:Particle Accelerators; D004369:Pentetic Acid / Q000031:analogs & derivatives; D011786:Quality Control; D016634:Radiosurgery / Q000379:methods* / Q000592:standards; D013238:Stereotaxic Techniques
D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA