[Mulleroblastoma of the uterus. Role of chemotherapy. A case report].
A case of mulleroblastoma, a malignant mixed Muller tumour, of the uterine body was observed in a 51-year-old patient. This is a rare but severe tumour. Clinically, there is a long latence period and early haematogenous metastases leading to failure of radiotherapy and surgical treatment. Recent data, particularly from immunohistochemistry studies, would suggest that the epithelial component plays a major role in pathogenesis. A therapeutic approach combining surgery, aggressive chemotherapy and radiotherapy allows improved prognosis.
Antoine
J M
JM
Service de Gynécologie-obstétrique, Hpital Tenon, Paris.
André
T
T
Antoine
M
M
Lotz
J P
JP
Salat-Baroux
J
J
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007044:Hysterectomy; D007150:Immunohistochemistry; D008875:Middle Aged; D018200:Mixed Tumor, Mullerian / Q000188:drug therapy* / Q000473:pathology; D011379:Prognosis; D014594:Uterine Neoplasms / Q000188:drug therapy* / Q000473:pathology; D014747:Vinblastine / Q000008:administration & dosage
D014747:Vinblastine; D004317:Doxorubicin; D003520:Cyclophosphamide; D005472:Fluorouracil