Successful pregnancy in a familial Mediterranean fever patient following assisted reproduction.
We conclude that untreated women with FMF have up to a 30% incidence of infertility due to ovulatory dysfunction and peritoneal adhesions. Some of these women conceive during ovulation induction with or without insemination. We have described the first case of a successful and normal pregnancy in a patient with FMF following in vitro fertilization (IVF) while on prophylaxis colchicine therapy after other treatments for infertility were unsuccessful.
Ditkoff
E C
EC
Department of Obstetrics and Gynecology, Columbia-Presbyterian Medical Center, Columbia University, New York, New York 10032, USA.
Sauer
M V
MV
D000328:Adult; D000686:Amyloidosis / Q000209:etiology / Q000517:prevention & control; D003078:Colchicine / Q000627:therapeutic use; D010505:Familial Mediterranean Fever / Q000188:drug therapy / Q000235:genetics / Q000503:physiopathology*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D010535:Laparoscopy; D008297:Male; D010062:Ovulation Induction; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy; D000267:Tissue Adhesions / Q000150:complications
D003078:Colchicine