Intracranial plasmacytoma: a case report.
Multiple myeloma may have extraosseous manifestations in the cranial region. It may be a solitary intracranial tumour without any other signs of multiple myeloma, or intracranial disease may be a part of generalised disease, as in the present case. Our patient had received chemotherapy for multiple myeloma for 9 months, with good response. However, her condition suddenly deteriorated, with signs of increased intracranial pressure and a 5-cm-diameter tumour infiltrating the meninges and brain was found in the left temporal fossa. The radiological diagnosis, based on contrast-enhanced CT and angiography, was not straightforward or specific for plasmacytoma, as chemotherapy for the extracranial disease had been successful. Diseases such as meningioma, metastasis, lymphoma, chondrosarcoma or haemangioma had to be considered.
Mäntylä
R
R
Department of Radiology, Töölö Hospital, Helsinki, Finland.
Kinnunen
J
J
Böhling
T
T
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D002533:Cerebral Angiography; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007146:Immunoglobulin lambda-Chains / Q000032:analysis; D008279:Magnetic Resonance Imaging; D008578:Meninges / Q000473:pathology; D009101:Multiple Myeloma / Q000175:diagnosis* / Q000188:drug therapy; D009460:Neurologic Examination; D012888:Skull Neoplasms / Q000175:diagnosis / Q000188:drug therapy; D013100:Sphenoid Bone / Q000473:pathology; D013702:Temporal Lobe / Q000473:pathology
D007146:Immunoglobulin lambda-Chains