28833, a selective kynurenine 3-hydroxylase inhibitor. Effects on the kynurenine pathway metabolites in the gerbil.
Cini
M
M
Pharmacia, R&D CNS, Nerviano Milano, Italy.
Bormetti
R
R
Marconi
M
M
Molinari
A
A
Veneroni
O
O
Varasi
M
M
Schwarcz
R
R
Speciale
C
C
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D002087:Butyrates / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005260:Female; D005849:Gerbillinae; D007736:Kynurenic Acid / Q000097:blood / Q000378:metabolism*; D007737:Kynurenine / Q000097:blood / Q000378:metabolism*; D050601:Kynurenine 3-Monooxygenase; D008297:Male; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors*; D051381:Rats; D017207:Rats, Sprague-Dawley
D002087:Butyrates; D004791:Enzyme Inhibitors; C104254:FCE 28833; D007737:Kynurenine; D006899:Mixed Function Oxygenases; D050601:Kynurenine 3-Monooxygenase; D007736:Kynurenic Acid