15-deoxyspergualin downregulates MHC class II antigen expression and cell migration in models of graft-versus-host and host-versus-graft disease.
Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.
A M
AM
Waaga
F
F
Fändrich
M
M
Krzymanski
V
V
Eckstein
C
C
Herwartz
W
W
Muller-Ruchholtz
M E
ME
Russell
D000818:Animals; D005786:Gene Expression Regulation / Q000187:drug effects; D005802:Genes, MHC Class II / Q000187:drug effects*; D006086:Graft vs Host Disease / Q000276:immunology* / Q000473:pathology; D006146:Guanidines / Q000494:pharmacology*; D000949:Histocompatibility Antigens Class II / Q000096:biosynthesis*; D006789:Host vs Graft Reaction / Q000276:immunology*; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007249:Inflammation; D007421:Intestine, Small / Q000473:pathology / Q000637:transplantation*; D008198:Lymph Nodes / Q000276:immunology*; D008297:Male; D051381:Rats; D011917:Rats, Inbred Lew; D011919:Rats, Inbred Strains; D013154:Spleen / Q000276:immunology; D016042:Transplantation, Heterotopic; D014184:Transplantation, Homologous / Q000276:immunology* / Q000473:pathology
D006146:Guanidines; D000949:Histocompatibility Antigens Class II; D007166:Immunosuppressive Agents; C037258:gusperimus