Familial thrombocytosis in infancy presenting with a leukaemoid reaction.
Familial thrombocytosis (FT) is a hereditary disorder probably involving the regulation of megakaryopoiesis. This report is the first documented case of FT in infancy. The clinical course was complicated by a leukaemoid reaction which lasted for several months, in combination with failure to thrive and hepatosplenomegaly. At the age of 5 years the patient, with the exception of thrombocytosis, is healthy and without medication.
van Dijken
P J
PJ
University Hospital for Childŕen and Youth Het Wilhelmina Kinderziekenhuis, Utrecht, The Netherlands.
Woldendorp
K H
KH
van Wouwe
J P
JP
D006801:Humans; D007223:Infant; D007955:Leukemoid Reaction / Q000150:complications / Q000175:diagnosis; D008297:Male; D010375:Pedigree; D013922:Thrombocytosis / Q000150:complications / Q000235:genetics*