Monosomy 22 and del(10)(p12) in an ameloblastoma previously diagnosed as an adenoid cystic carcinoma of the salivary gland.
Short-term cultures of a collagenase disaggregated ameloblastoma previously diagnosed as an adenoid cystic carcinoma of the salivary gland were shown by cytogenetic analysis to have the clonal karyotype 45,XY,del(10)(p12),-22. The data may indicate that the loss of genes of chromosome 22, as well as of 10p, could be a critical event in the evolutionary pattern of odontogenic neoplasias.
Departamento de Biologia, Instituto de Biociências, Letras e Ciências Exatas de São José do Rio Preto, UNESP, São José do Rio Preto, São Paulo, Brazil.
N
N
Barril
P R
PR
Oliveira
E H
EH
Tajara
D000328:Adult; D000564:Ameloblastoma / Q000235:genetics* / Q000473:pathology; D003528:Carcinoma, Adenoid Cystic / Q000473:pathology; D006801:Humans; D007573:Jaw Neoplasms / Q000235:genetics* / Q000473:pathology; D008297:Male; D012468:Salivary Gland Neoplasms / Q000473:pathology