Monitoring low-dose warfarin therapy by a central laboratory and implications for clinical trials and patient care. The Coumadin Aspirin Reinfarction (CARS) Pilot Study Group.
The central laboratory provides International Normalized Ratio results in close agreement with the local laboratory for monitoring the anticoagulant effect of low-dose warfarin. A central laboratory may have practical advantages for patients in rural areas that lack laboratory facilities for anticoagulant monitoring.
Raskob
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Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City 73190, USA.
Durica
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Owen
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Comp
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D000368:Aged; D000925:Anticoagulants / Q000097:blood* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007753:Laboratories; D008297:Male; D008875:Middle Aged; D010314:Partial Thromboplastin Time; D010347:Patient Care Planning; D011446:Prospective Studies; D013048:Specimen Handling; D014859:Warfarin / Q000097:blood* / Q000627:therapeutic use
D000925:Anticoagulants; D014859:Warfarin