Impact of sumatriptan on clinic utilization and costs of care in migraineurs.
BACKGROUND
Although migraine headaches affect a large segment of the population, no objective measure of therapeutic success is currently available. Comparing visit frequency and associated costs of care before and after introduction of a new therapy represents an important surrogate measure of success.


METHODS
One hundred four patients regularly attending a headache clinic for migraines at a tertiary care hospital were instructed in the use of a new abortive migraine therapy. Medical appointment and financial systems were searched retrospectively for visit frequency and associated patient care and institutional costs. The number of visits and mean costs 18 months before and after initiation of therapy were compared using the signed rank test and paired t-test, respectively.


RESULTS
The median number of visits made by study subjects to the headache clinic fell significantly following sumatriptan test dosing (P < 0.001). Prior to the new treatment, mean total patient care and institutional costs were $228.59 and $112.81 per person, respectively, and fell to $135.93 and $78.16 (P < 0.001) after therapy began.


CONCLUSIONS
These data suggest that many patients with migraine benefit from sumatriptan, seek medical attention in a headache clinic less often, and incur fewer costs following initiation of treatment with this drug.
Department of General Internal Medicine, Cleveland Clinic Foundation, OH 44195, USA.
D G
DG
Litaker
G D
GD
Solomon
J R
JR
Genzen
D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D017048:Health Care Costs; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000188:drug therapy* / Q000191:economics*; D018710:Pain Clinics / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D017366:Serotonin Receptor Agonists / Q000191:economics* / Q000627:therapeutic use*; D018170:Sumatriptan / Q000191:economics* / Q000627:therapeutic use*
D017366:Serotonin Receptor Agonists; D018170:Sumatriptan