The structure of lactate dehydrogenase from Plasmodium falciparum reveals a new target for anti-malarial design.
C R
CR
Dunn
M J
MJ
Banfield
J J
JJ
Barker
C W
CW
Higham
K M
KM
Moreton
D
D
Turgut-Balik
R L
RL
Brady
J J
JJ
Holbrook
D000818:Animals; D000962:Antimalarials; D015195:Drug Design; D004791:Enzyme Inhibitors; D007770:L-Lactate Dehydrogenase / Q000037:antagonists & inhibitors / Q000737:chemistry*; D008958:Models, Molecular; D009243:NAD / Q000737:chemistry* / Q000378:metabolism; D010072:Oxamic Acid / Q000737:chemistry; D010963:Plasmodium falciparum / Q000201:enzymology*; D011487:Protein Conformation
D000962:Antimalarials; D004791:Enzyme Inhibitors; D009243:NAD; D007770:L-Lactate Dehydrogenase; D010072:Oxamic Acid