Immunocytochemical localization of aromatic L-amino acid decarboxylase and catechol-O-methyltransferase in blood vessel wall of the human dental pulp.
Relative large amounts of DOPA as compared with the concentrations of norepinephrine are found in human dental pulp. AADC and COMT are localized in blood vessel walls of human dental pulp. This localization suggests a functional relationship between COMT and AADC with regard to the metabolism of DOPA.
Department of Periodontology, Matsumoto Dental College, Nagano, Japan.
T
T
Nomura
K
K
Inoue
C R
CR
Creveling
F
F
Komatsu
N
N
Ohta
T
T
Chino
N
N
Karasawa
I
I
Nagatsu
D000328:Adult; D001142:Aromatic-L-Amino-Acid Decarboxylases / Q000378:metabolism*; D001808:Blood Vessels / Q000201:enzymology; D002394:Catechol O-Methyltransferase / Q000378:metabolism*; D003782:Dental Pulp / Q000098:blood supply* / Q000378:metabolism; D004295:Dihydroxyphenylalanine / Q000378:metabolism; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009638:Norepinephrine / Q000378:metabolism; D014018:Tissue Distribution
D004295:Dihydroxyphenylalanine; D002394:Catechol O-Methyltransferase; D001142:Aromatic-L-Amino-Acid Decarboxylases; D009638:Norepinephrine