Acrodermatitis chronica atrophicans in an 11-year-old girl.
We report a case of acrodermatitis chronica atrophicans in an 11-year-old girl living in an area endemic for Lyme borreliosis. The diagnosis was first made on the basis of clinical, histopathological and serological findings. Moreover, Borrelia burgdorferi-specific DNA was amplified from lesional skin by polymerase chain reaction. Intravenous treatment with ceftriaxone (2 g once daily) for 2 weeks was initiated. The skin changes clearly responded to the therapy, and Borrelia burgdorferi-specific gene segments were no longer detectable by polymerase chain reaction. This is the first report of molecular-proven acrodermatitis chronica atrophicans in childhood. The occurrence of this late skin manifestation of Lyme borreliosis in children is reviewed.
Department of Dermatology, Karl Franzens University, Graz, Austria.
R R
RR
Muellegger
E M
EM
Schluepen
M M
MM
Millner
H P
HP
Soyer
M
M
Volkenandt
H
H
Kerl
D000169:Acrodermatitis / Q000382:microbiology* / Q000473:pathology; D015748:Borrelia burgdorferi Group / Q000302:isolation & purification; D002648:Child; D004269:DNA, Bacterial / Q000032:analysis; D005260:Female; D006801:Humans; D008193:Lyme Disease / Q000175:diagnosis* / Q000473:pathology; D017192:Skin Diseases, Bacterial / Q000175:diagnosis* / Q000473:pathology
D004269:DNA, Bacterial