Reproducibility of the cardiovascular reactivity to a computerized version of the Stroop stress test in normotensive and hypertensive subjects.
The 1-month reproducibility of haemodynamic and sympathoadrenal responses to a standardized mental stress test was studied in ten normotensive and ten hypertensive individuals. The stress test was a computerized adaptation of the Stroop test and sympathetic activity was evaluated by measuring urinary catecholamine excretion. Three-way analysis of variance (stress, session, blood pressure) revealed significant increases in systolic and diastolic blood pressures and in heart rate during the stress test. Test-retest correlation coefficients for basal stress levels, and stress-induced variations were significant (r from 0.59 to 0.88). The stress test induced a significant increase in urinary noradrenaline excretion with large intra- and interindividual variability. The significant test-retest correlations and the lack of period effect for haemodynamic parameters indicated good temporal stability. However, a slight decrease in stress-induced reactivity was observed. This standardized mental stress test may be useful in epidemiological and therapeutic trials to measure blood pressure and heart rate responses, but measurement of urinary catecholamine excretion does not provide any additional information.
Département de Néphrologie et d'Hypertension Artérielle, CNRS URA, Lyon, France.
J P
JP
Fauvel
N
N
Bernard
M
M
Laville
S
S
Daoud
N
N
Pozet
P
P
Zech
D000328:Adult; D001794:Blood Pressure / Q000502:physiology; D003220:Conflict, Psychological; D003936:Diagnosis, Computer-Assisted; D004837:Epinephrine / Q000652:urine; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009638:Norepinephrine / Q000652:urine; D015203:Reproducibility of Results; D012146:Rest / Q000502:physiology; D013315:Stress, Psychological / Q000503:physiopathology*
D009638:Norepinephrine; D004837:Epinephrine