Do calcium antagonists cause death, gastrointestinal bleeding, and cancer?
Recent reports from an uncontrolled, retrospective cohort study in elderly hypertensives implicate short-acting calcium antagonists in causing increased mortality, gastrointestinal bleeding, and cancer. Multiple serious flaws in the study make the validity of these findings highly suspect and there remains absolutely no evidence that long-acting calcium antagonists are unsafe.
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Kaplan
D002121:Calcium Channel Blockers / Q000009:adverse effects* / Q000627:therapeutic use; D016022:Case-Control Studies; D006471:Gastrointestinal Hemorrhage / Q000139:chemically induced*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D009203:Myocardial Infarction / Q000139:chemically induced*; D009369:Neoplasms / Q000139:chemically induced*
D002121:Calcium Channel Blockers