Antisocial personality disorder, childhood delinquency, and frontal brain functioning: EEG and neuropsychological findings.
This experiment examined the ability of EEG activity and neuropsychological testing to predict both antisocial personality disorder (ASP) and retrospective self-ratings of early childhood problem behaviors (CPB). Regression analyses found that increased frontal left-hemisphere EEG activation was associated with a decreased likelihood of the diagnosis of ASP or CPB. An association was also found between several motor tests of the Luria-Nebraska and Porteus Maze Test scores and CPB/ASP. The current findings suggest that ASP and CPB are associated with variations in frontal lobe functioning. They further suggest that disturbances in prefrontal functioning may be a common biological ground that links ASP, substance abuse, and biological mechanisms of reinforcement.
Deckel
A W
AW
Department of Psychiatry, University of Connecticut Medical School, Farmington 06030, USA. Deckel@psychiatry.uchc.edu
Hesselbrock
V
V
Bauer
L
L
D000328:Adult; D000987:Antisocial Personality Disorder / Q000503:physiopathology*; D002648:Child; D002653:Child Behavior Disorders / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D004569:Electroencephalography; D005625:Frontal Lobe / Q000503:physiopathology*; D007839:Functional Laterality; D006801:Humans; D016015:Logistic Models; D008297:Male; D015999:Multivariate Analysis; D009483:Neuropsychological Tests; D011379:Prognosis; D012054:Reinforcement, Psychology; D012189:Retrospective Studies; D019966:Substance-Related Disorders / Q000517:prevention & control