[Effects of anesthesia with inhalation anesthetics on excitation, conduction and refractory parameters of the heart. Experiments in dogs].
Cardiac excitation, conduction, and refractory parameters of the heart were investigated in 40 beagle dogs to obtain basic values under the influence of the following 9 inhalation anaesthetic regimes using HIS-bundle electrography and programmed stimulation: 1. halothane; 2. enflurane; 3. isoflurane; 4. halothane+nitrous oxide; 4. enflurane+nitrous oxide; 6. isoflurane+nitrous oxide; 7. alfentanil/midazolam/succinylcholine+nitrous oxide; 8. fentanyl/midazolam/pancuronium bromide+nitrous oxide; 9. propofol+nitrous oxide. It could be shown that inhalation anaesthetics under laboratory conditions exert some influences on the observed cardiac parameters, although they are not as strong as those of intravenous anaesthetics. Therefore their effects should be considered in experiments with other substances or in cardiovascular results.
Experimentelle Chirurgie (Zentrum für Chirurgie, Chirurgische Klinik und Poliklinik, Rheinischen Friedrich-Wilhelms-Universität Bonn.
N
N
Hahn
U
U
Hörnchen
W
W
Eichelkraut
D000769:Anesthesia, Inhalation; D018685:Anesthetics, Inhalation; D000818:Animals; D001283:Atrioventricular Node / Q000187:drug effects; D002036:Bundle of His / Q000187:drug effects; D004285:Dogs; D006321:Heart / Q000187:drug effects* / Q000294:innervation / Q000502:physiology; D006329:Heart Conduction System / Q000187:drug effects*; D012032:Refractory Period, Electrophysiological / Q000187:drug effects*; D012849:Sinoatrial Node / Q000187:drug effects
D018685:Anesthetics, Inhalation