Role of puncture and aspiration in expectant management of simple ovarian cysts: a randomised study.
OBJECTIVE
To assess the potential of expectant management for simple ovarian cysts diagnosed by transabdominal or transvaginal ultrasonography. To compare the results of needle aspiration with those achieved with simple observation.


METHODS
Randomised trial.


METHODS
Hospital department of obstetrics and gynaecology.


METHODS
278 women with simple cysts randomly allocated to simple observation (143) or ultrasound guided fine needle aspiration (135) between 1990 and 1994.


METHODS
Resolution of cyst or development of malignancy.


RESULTS
After six months 269 were available for follow up. The rate of resolution was 46% (59/128) with aspiration and 44.6% (63/141) with observation. Only the diameter of the cyst (P < 0.0001) was a significant independent prognostic factor for resolution in a multivariate analysis. Age and treatment had no significant effect. One woman was subsequently found to have borderline malignant changes on histopathological examination. Her cyst was detected by transabdominal ultrasonography.


CONCLUSIONS
Expectant management for up to six months does not cause risks for the patients and allows spontaneous resolution in over a third of cases, avoiding the costs and risks of unnecessary surgery. Aspiration does not provide better results than simple observation.
Department of Obstetrics and Gynaecology, Ospedale San Gerardo di Monza, III Branch of the University of Milan, Italy.
G
G
Zanetta
A
A
Lissoni
V
V
Torri
C
C
Dalla Valle
D
D
Trio
G
G
Rangoni
C
C
Mangioni
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D004322:Drainage / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D015999:Multivariate Analysis; D010048:Ovarian Cysts / Q000628:therapy*; D012008:Recurrence; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional