Enzymatic programming of apoptotic cell death.
The phenomenon of 'apoptosis' was recognized in the early seventies. However, most of the mechanistic insights into the process of apoptotic cell death came about only in the last few years. It is now clear that a variety of enzymes constitute the major mediators of this process. The present article reviews the possible interrelationships between these enzymes and proposes a model for enzymatic programming of apoptotic cell death.
Mundle
S D
SD
Rush Cancer Institute, Rush-Presbyterian-St. Luke's Medical Centre, Chicago, Ill 60612, USA.
Gregory
S A
SA
Preisler
H D
HD
Raza
A
A
D000818:Animals; D017209:Apoptosis / Q000187:drug effects*; D004798:Enzymes / Q000494:pharmacology*; D006801:Humans
D004798:Enzymes