Threshold models in a methadone programme evaluation.
The degree of non-compliance with a methadone programme is such that a zero is often recorded as the response variable. Such outcome variables cannot be transformed to normality in order to investigate a regression relationship between the response variable and various risk or treatment variables. The presence of a random effect as well in this regression causes added difficulty in the analysis. We show here that use of threshold models can provide a satisfactory solution to both these problems.
Saei
A
A
National Centre for Epidemiology and Population Health, Australian National University, Canberra, Australia.
Ward
J
J
McGilchrist
C A
CA
D001315:Australia; D001569:Benzodiazepines; D003042:Cocaine; D015658:HIV Infections / Q000517:prevention & control* / Q000635:transmission; D003932:Heroin; D006801:Humans; D008691:Methadone / Q000627:therapeutic use*; D015233:Models, Statistical; D010349:Patient Compliance; D011314:Preventive Health Services; D015397:Program Evaluation; D016032:Randomized Controlled Trials as Topic; D012044:Regression Analysis; D012307:Risk Factors; D019966:Substance-Related Disorders / Q000150:complications / Q000188:drug therapy*
D001569:Benzodiazepines; D003932:Heroin; D003042:Cocaine; D008691:Methadone