Computer simulation of human blood flow and vascular resistance.
Organ blood flows and associated vascular resistances have been investigated through the use of a Microsoft Windows-compatible computer program which employs Monte Carlo simulations based on the system's principal components. This approach replicates the system's behavior by maintaining proper correlations between all variables in the system as well as allowing for modulation of the system by its inherent uncertainties. By applying various external constraints, such as a specific age, weight, height and/or blood pressure, the simulations allow for insights to be obtained about the behavior of individual patients. In particular, patient specific organ blood flows and associated vascular resistances can be determined as a function of a patient's age, weight, height and blood pressure.
School of Pharmacy, University of Wisconsin, Madison 53706, USA.
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Burnette
D000328:Adult; D002138:Calibration; D003198:Computer Simulation; D003626:Data Display; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D008838:Microcomputers; D008955:Models, Cardiovascular; D009010:Monte Carlo Method; D012984:Software; D014584:User-Computer Interface; D014655:Vascular Resistance / Q000502:physiology*