Reactivation of caprine herpesvirus 1 in latently infected goats.
The authors report CapHV.1 reactivation in two latently infected adult goats treated with dexamethasone (DMS) (4.40 mg/kg BW) for 6 days. Virus was reisolated from vaginal swabs from the 3rd to the 12th day post-treatment with DMS and from nasal swabs for 2 days (6th and 7th day post-treatment). The animals also showed an increase of neutralizing antibody (SN) titer to CapHV.1 3 weeks after the end of treatment with DMS.
Buonavoglia
C
C
Istituto di Malattie Infettive e Parassitarie Degli Animali, Facoltà di Medicina Veterinaria, Valenzano (BA), Italy.
Tempesta
M
M
Cavalli
A
A
Voigt
V
V
Buonavoglia
D
D
Conserva
A
A
Corrente
M
M
D000818:Animals; D002460:Cell Line; D003907:Dexamethasone / Q000627:therapeutic use; D015511:Goat Diseases / Q000821:virology*; D006041:Goats; D006561:Herpes Simplex / Q000662:veterinary* / Q000821:virology; D009500:Neutralization Tests; D012150:Polymorphism, Restriction Fragment Length; D018139:Simplexvirus / Q000254:growth & development* / Q000302:isolation & purification; D010948:Viral Plaque Assay; D014775:Virus Activation; D017735:Virus Latency
D003907:Dexamethasone