Aggressive management of intra-arterial Temazepam injection.
Intravenous injection of the oral formulation of Temazepam is a common form of drug abuse. At the request of the Home Office, manufacturers have developed solid dose forms to replace the liquid filled capsules, but a number of cases of accidental intra-arterial injection of the new formulation have been reported, with varying management strategies advocated. A case is presented where prompt aggressive management using surgical and pharmacological measures resulted in complete limb salvage. Previous reported cases and management options are discussed.
Surgical Department, Cambridge Military Hospital, Aldershot, Hants.
I D
ID
Russell
G G
GG
Kane
C A
CA
Royle
D S
DS
Jackson
D000328:Adult; D001916:Brachial Artery; D002626:Chemistry, Pharmaceutical; D003161:Compartment Syndromes / Q000139:chemically induced; D011464:Epoprostenol / Q000627:therapeutic use; D006801:Humans; D007269:Injections, Intra-Arterial / Q000009:adverse effects*; D008297:Male; D009543:Nifedipine / Q000627:therapeutic use; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D016879:Salvage Therapy; D015819:Substance Abuse, Intravenous / Q000150:complications / Q000628:therapy*; D013693:Temazepam; D014665:Vasodilator Agents / Q000627:therapeutic use
D010975:Platelet Aggregation Inhibitors; D014665:Vasodilator Agents; D013693:Temazepam; D011464:Epoprostenol; D009543:Nifedipine