A lamb-meat-based formula for infants allergic to casein hydrolysate formulas.
Ten infants with colitis due to milk protein allergy, presenting as hematochezia, whose symptoms did not resolve with the use of hydrolyzed cow-milk-based formulas, were treated with a modular lamb-meat-based formula (LOP). The patients were followed up for 3 months to 5 years. Prompt resolution of symptoms was achieved. In three patients, increased levels of creatinine and blood urea nitrogen and mild metabolic acidosis were noted, all returning to normal after the protein intake was lowered. All patients had normal growth. Seven patients were able to tolerate cow milk protein or soy at age 9-15 months. The LOP formula is well tolerated and is a safe alternative formula for infants allergic to cow milk hydrolysate formula.
Department of Pediatric Gastroenterology, New England Medical Center Hospital, Boston, MA 02111, USA.
B
B
Weisselberg
Y
Y
Dayal
J F
JF
Thompson
M S
MS
Doyle
B
B
Senior
R J
RJ
Grand
D000818:Animals; D001806:Blood Urea Nitrogen; D002364:Caseins / Q000009:adverse effects / Q000276:immunology*; D003404:Creatinine / Q000097:blood; D003968:Diarrhea, Infantile / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D005512:Food Hypersensitivity / Q000276:immunology; D005526:Food, Formulated; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007223:Infant; D007225:Infant Food; D007231:Infant, Newborn; D008297:Male; D008461:Meat Products; D016269:Milk Hypersensitivity / Q000150:complications* / Q000276:immunology / Q000628:therapy; D008894:Milk Proteins / Q000009:adverse effects / Q000276:immunology; D011492:Protein Hydrolysates / Q000009:adverse effects / Q000276:immunology*; D012756:Sheep
D002364:Caseins; D008894:Milk Proteins; D011492:Protein Hydrolysates; C026375:trypticase-soy broth; D003404:Creatinine