Outcome of pregnancies in women with treated or untreated hyperprolactinemia.
The outcome of 103 pregnancies in 64 women with constant hyperprolactinemia was evaluated. Seventy-eight pregnancies had been induced with bromocriptine and 25 occurred without any treatment. In all, 66% of the pregnancies ended in delivery, 17% in miscarriage, 10% in tubal pregnancy and 7% in induced abortion. The pregnancy of women with untreated hyperprolactinemia was more frequently ectopic when compared to those in women treated by bromocriptine. Obstetric complications as well as signs of tumoral enlargement during pregnancy were rare in hyperprolactinemic women treated or untreated with bromocriptine. Untreated hyperprolactinemia as a risk factor in tubal pregnancy is proposed.
Department of Obstetrics and Gynecology, University Hospital, Tampere, Finland.
A M
AM
Rossi
S
S
Vilska
P K
PK
Heinonen
D000028:Abortion, Induced; D000022:Abortion, Spontaneous; D000236:Adenoma / Q000150:complications; D000328:Adult; D001971:Bromocriptine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006966:Hyperprolactinemia / Q000150:complications*; D007247:Infertility, Female / Q000209:etiology / Q000628:therapy*; D010062:Ovulation Induction; D010911:Pituitary Neoplasms / Q000150:complications; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy*; D011256:Pregnancy Outcome; D011274:Pregnancy, Tubal
D001971:Bromocriptine