The role of p53 loss in genomic instability and tumor progression in a murine mammary cancer model.
Donehower
L A
LA
Division of Molecular Virology, Baylor College of Medicine, Houston, TX 77030, USA.
Godley
L A
LA
Aldaz
C M
CM
Pyle
R
R
Shi
Y P
YP
Pinkel
D
D
Gray
J
J
Bradley
A
A
Medina
D
D
Varmus
H E
HE
D000782:Aneuploidy; D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D003433:Crosses, Genetic; D018450:Disease Progression; D005260:Female; D018390:Gene Targeting; D016158:Genes, p53; D008297:Male; D008325:Mammary Neoplasms, Experimental / Q000235:genetics* / Q000473:pathology; D051379:Mice; D018345:Mice, Knockout; D008822:Mice, Transgenic; D009374:Neoplasms, Experimental / Q000235:genetics; D011518:Proto-Oncogene Proteins / Q000235:genetics; D016159:Tumor Suppressor Protein p53 / Q000172:deficiency* / Q000502:physiology; D051153:Wnt Proteins; D029961:Zebrafish Proteins
D011518:Proto-Oncogene Proteins; D016159:Tumor Suppressor Protein p53; D051153:Wnt Proteins; D029961:Zebrafish Proteins