Degradation of the fluoroquinolone enrofloxacin by wood-rotting fungi.
The veterinary fluoroquinolone enrofloxacin was degraded in vitro by four species of wood-rotting fungi growing on wetted wheat straw containing carbonyl-14C-labeled drug. A maximum 14CO2 production of 17% per week was observed with the brown rot fungus Gloeophyllum striatum, resulting in up to 53% after 8 weeks. However, rates reached at most 0.2 and 0.9% per week, if enrofloxacin was preadsorbed to native or gamma ray-sterilized soil, respectively.
Bundesforschungsanstalt für Landwirtschaft, Institut für Bodenbiologie, Braunschweig, Germany.
R
R
Martens
H G
HG
Wetzstein
F
F
Zadrazil
M
M
Capelari
P
P
Hoffmann
N
N
Schmeer
D000327:Adsorption; D000363:Agaricales / Q000378:metabolism; D000890:Anti-Infective Agents / Q000378:metabolism*; D001203:Ascomycota / Q000378:metabolism; D001487:Basidiomycota / Q000378:metabolism; D001673:Biodegradation, Environmental; D000077422:Enrofloxacin; D024841:Fluoroquinolones; D005658:Fungi / Q000254:growth & development / Q000378:metabolism*; D011124:Polyporaceae / Q000378:metabolism; D015363:Quinolones / Q000378:metabolism*; D012987:Soil; D013997:Time Factors; D014908:Triticum
D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015363:Quinolones; D012987:Soil; D000077422:Enrofloxacin