Kynurenine-3-hydroxylase and its selective inhibitors. Molecular modeling studies.
Istituto di Chimica e Tecnologia del Farmaco, Universitá degli Studi di Perugia, Italy.
G
G
Costantino
L
L
Mattoli
F
F
Moroni
B
B
Natalini
R
R
Pellicciari
D000818:Animals; D001665:Binding Sites; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D007737:Kynurenine / Q000031:analogs & derivatives / Q000737:chemistry / Q000494:pharmacology; D050601:Kynurenine 3-Monooxygenase; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors* / Q000737:chemistry*; D008958:Models, Molecular; D018696:Neuroprotective Agents / Q000737:chemistry / Q000494:pharmacology*; D011487:Protein Conformation
D004791:Enzyme Inhibitors; D018696:Neuroprotective Agents; D007737:Kynurenine; D006899:Mixed Function Oxygenases; D050601:Kynurenine 3-Monooxygenase