Sperm angiotensin-converting enzyme activity in Chernobyl victims and patients with chronic prostatitis.
The method for determination of angiotensin-converting enzyme activity in human spermatozoa and seminal plasma was developed. The number of total and active-motile spermatozoa was shown to be lower in Chernobyl victims than in healthy donors. The specific activity of angiotensin-converting enzyme in spermatozoa from Chernobyl victims was 12 times higher than that in donors. Similar results, although to a lesser extent, were observed in patients with chronic prostatitis. In contrast, the enzyme activity in blood serum and seminal plasma was identical for all subjects investigated.
Sakharov IYu
Department of Chemistry, M.V. Lomonosov State University, Moscow, Russia.
Evdokimov
V V
VV
Atochina
E A
EA
D002908:Chronic Disease; D006801:Humans; D008297:Male; D007703:Peptidyl-Dipeptidase A / Q000378:metabolism*; D011210:Power Plants; D011472:Prostatitis / Q000201:enzymology*; D018788:Radioactive Hazard Release; D012661:Semen / Q000201:enzymology*; D014455:Ukraine
D007703:Peptidyl-Dipeptidase A