Absence of association between the angiotensin-converting enzyme gene polymorphism and borderline hypertension in men of St Petersburg, Russia.
We studied the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene in 131 young males with borderline hypertension (BHT) and in 87 normotensive (NT) young males as a control group using polymerase chain reaction (PCR) technique. The allele frequencies of insertion and deletion ACE alleles were not different in both groups. These results suggest that I/D polymorphism of the ACE gene is not associated with a BHT in males of St Petersburg.
St Petersburg Pediatric Medical Academy, Russia.
V
V
Popov
E
E
Fomicheva
J
J
Kovalev
E
E
Schwartz
D000328:Adult; D005819:Genetic Markers / Q000235:genetics; D006801:Humans; D006973:Hypertension / Q000235:genetics* / Q000503:physiopathology; D008297:Male; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012426:Russia / Q000453:epidemiology
D005819:Genetic Markers; D007703:Peptidyl-Dipeptidase A