Platelets and antiphospholipid antibodies.
The involvement of platelets in the antiphospholipid syndrome is complex and the full pathogenic significance is not fully understood. The binding of aPL antibodies to the platelet membrane may result in the thrombopenia and further haemostatic activation.
Machin
S J
SJ
Haematology Department, University College London, UK.
D017152:Antibodies, Antiphospholipid / Q000502:physiology*; D016736:Antiphospholipid Syndrome / Q000209:etiology; D001792:Blood Platelets / Q000502:physiology*; D006023:Glycoproteins / Q000502:physiology; D006801:Humans; D053482:beta 2-Glycoprotein I
D017152:Antibodies, Antiphospholipid; D006023:Glycoproteins; D053482:beta 2-Glycoprotein I