Dental findings in parents of children with cleft lip and palate.
The incidence of dental abnormalities in the cleft lip and palate population has been reported to be much higher than in the normal population. The role of genes in the production of a cleft lip and palate, and dental anomalies is thought to be complex, with autosomal dominant, recessive, and x-linked genes all playing a role. Noncleft parents can carry some of the cleft lip and palate genes, which produce clinically subtle manifestations in their facial skeleton. The purpose of this study was to look for evidence of increased dental anomalies in the non-cleft parents of cleft lip and palate children. The dentitions of the parents of 60 children with different types of cleft lip and palate were examined prospectively to see whether or not they exhibited features found more readily in the cleft lip and palate rather than did the normal population. Their dentitions were studied to record the following dental features: congenitally missing teeth, supernumerary teeth, or morphologic changes of the crowns of the permanent teeth. The number and position of any frenal attachments were also recorded. The results of this study did not show any differences in incidence of dental anomalies from the noncleft population. There was no evidence to support the hypothesis that congenital absence of lateral incisors is a microform of cleft lip and palate. Further, these results also failed to reveal any consistent pattern in the number and position of frenal attachments.
Department of Craniofacial Surgery, Great Ormond Street Hospital, London, U.K.
P J
PJ
Anderson
A L
AL
Moss
D000293:Adolescent; D000328:Adult; D000848:Anodontia / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D002971:Cleft Lip / Q000235:genetics*; D002972:Cleft Palate / Q000235:genetics*; D005192:Family Health; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007742:Labial Frenum / Q000002:abnormalities; D008035:Lingual Frenum / Q000002:abnormalities; D008875:Middle Aged; D010290:Parents; D011795:Surveys and Questionnaires; D014071:Tooth Abnormalities / Q000235:genetics*; D019228:Tooth Crown / Q000002:abnormalities; D014096:Tooth, Supernumerary / Q000235:genetics