Bone uptake of vanadium in mice: simultaneous tracing of V, Se, Sr, Y, Zr, Ru and Rh using a radioactive multitracer.
The radioactive multitracer technique, which enables simultaneous tracing of a number of elements in a variety of bio-systems and an accurate comparison of their biobehavior, was employed in a study on uptake behavior of trace elements in various mice tissues, focusing on uptake of V by bone. We found that the bone uptake behavior of trace V closely resembles that of trace Sr and Y. It is suggested that V is a bone-seeking element which probably plays an important role in bone formation. The multitracer technique was thus shown to be useful for comparative studies of behavior of trace elements in living organisms.
School of Health Sciences, Faculty of Medicine, Kanazawa University, Ishikawa, Japan.
R
R
Amano
S
S
Enomoto
M
M
Nobuta
M
M
Sakamoto
R
R
Tsujioka
F
F
Ambe
D000818:Animals; D001842:Bone and Bones / Q000378:metabolism*; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D011868:Radioisotopes; D014131:Trace Elements / Q000493:pharmacokinetics*; D014639:Vanadium / Q000493:pharmacokinetics*
D011868:Radioisotopes; D014131:Trace Elements; D014639:Vanadium