No proof of HTLV-I/II in intravenous drug abusers with a high rate of HIV-1 infection in central Thailand.
Serum specimens of 1,074 intravenous drug abusers (IVDA) were examined for infection with HIV-1, HTLV-I and HTLV-II in central Thailand. Three hundred and sixty-two of the specimens were seropositive for HIV-1 (33.7%). The HIV-1 seropositive IVDAs exhibited increased seropositivity with age through group 40-44 and significantly decreased seropositivity over the age of 45. In contrast, no seropositivity to either HTLV-I or -II was detected in the samples tested by a particle-agglutination assay for HTLV followed by type-specific Western blotting for HTLV. Reference to previous reports suggested that the rate of HIV infection in IVDAs has decreased with no HTLV-I or HTLV-II in Thailand when compared with that of the HIV infection in 1992.
Virus Research Institute, Department of Medical Sciences, Thailand.
S
S
Saguanwongse
A
A
Muangpom
N
N
Ruchusatsawat
S
S
Wongcheree
P
P
Warachit
K
K
Miyamura
S
S
Yamazaki
M
M
Honda
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000372:Agglutination Tests; D015153:Blotting, Western; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000453:epidemiology / Q000276:immunology; D006679:HIV Seropositivity; D015497:HIV-1; D015490:HTLV-I Infections / Q000150:complications* / Q000453:epidemiology / Q000276:immunology; D015491:HTLV-II Infections / Q000150:complications* / Q000453:epidemiology / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016036:Seroepidemiologic Studies; D015819:Substance Abuse, Intravenous / Q000821:virology*; D013785:Thailand / Q000453:epidemiology