Preliminary findings on the expression of thymosin beta-10 in human breast cancer.
Paraffin sections from 30 human breast tissue specimens were stained with a specific antibody for thymosin beta-10, ATB10(38-43). The results showed that thymosin beta-10 was detected mainly in the malignant tissue, particularly in the cancerous cells, whereas the normal cell population around the lesions showed very weak staining. Also, the intensity of staining in the cancerous cells was proportionally increased with the increasing grade of the lesions.
Verghese-Nikolakaki
S
S
Institute of Radioisotopes and Radiodiagnostic Products, NCSR Demokritos, Athens, Greece.
Apostolikas
N
N
Livaniou
E
E
Ithakissios
D S
DS
Evangelatos
G P
GP
D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis*; D001943:Breast Neoplasms / Q000737:chemistry*; D018270:Carcinoma, Ductal, Breast / Q000737:chemistry*; D018275:Carcinoma, Lobular / Q000737:chemistry*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000032:analysis*; D013947:Thymosin / Q000032:analysis*
D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins; D013947:Thymosin; C039302:thymosin beta(10)