Occurrence of Borrelia garinii oculo-neuroborreliosis in Japan.
We report a 64-year-old Japanese man with oculo-neuroborreliosis. His clinical features consisted of polyarthralgia, keratoconjunctivitis, chorioretinitis, optic neuritis, confusion, and polyradiculitis. Assay of antibodies to Borrelia species detected IgG-antibody to B. garinii in both serum and CSF. Progressive declining of serum IgG antibody titer against Borrelia garinii, in parallel with clinical improvement, was observed after administration of ceftriaxone.
Yukitake
M
M
Department of Internal Medicine, Saga Medical School, Japan.
Kuroda
Y
Y
Kurohara
K
K
Matsui
M
M
Yasuda
A
A
Matsui
Y
Y
Oono
S
S
Kimura
K
K
Isogai
E
E
D000368:Aged; D001899:Borrelia Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000134:cerebrospinal fluid; D007075:Immunoglobulin M / Q000097:blood / Q000134:cerebrospinal fluid; D007564:Japan; D008297:Male; D009902:Optic Neuritis / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology*
D007074:Immunoglobulin G; D007075:Immunoglobulin M