A spectroscopic study of the interaction of the VO2+ cation with the two components of chondroitin sulfate.
The interaction of the vanadyl (IV) cation with N-acetyl-D-galactosamine, D-galactosamine, and D-glucuronic acid has been investigated by electron absorption spectroscopy at different metal to ligand ratios and pH values. In the case of D-glucuronic acid, a more detailed study was undertaken, using differential IR spectroscopy in solution. The results show that the cation interacts with the two nitrogenated molecules only at higher pH values, generating 2:1 ligand to metal complexes in which coordination occurs through two pairs of deprotonated OH groups of the rings. In the case of D-glucuronic acid, the IR-measurements allowed a wider insight into the structural characteristics of the complexes generated in acidic media. The involvement of the glycosidic oxygen atom in coordination, is suggested at pH = 3.
Etcheverry
S B
SB
Quimica Inorganica (QUINOR), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Argentina.
Williams
P A
PA
Baran
E J
EJ
D000116:Acetylgalactosamine / Q000737:chemistry* / Q000378:metabolism; D002413:Cations, Divalent; D002809:Chondroitin Sulfates / Q000737:chemistry / Q000378:metabolism*; D005688:Galactosamine / Q000737:chemistry* / Q000378:metabolism; D005965:Glucuronates / Q000737:chemistry* / Q000378:metabolism; D020723:Glucuronic Acid; D006863:Hydrogen-Ion Concentration; D008024:Ligands; D013054:Spectrophotometry, Atomic; D013055:Spectrophotometry, Infrared; D014638:Vanadates / Q000737:chemistry / Q000378:metabolism*
D002413:Cations, Divalent; D005965:Glucuronates; D008024:Ligands; D014638:Vanadates; D005688:Galactosamine; D020723:Glucuronic Acid; D002809:Chondroitin Sulfates; D000116:Acetylgalactosamine