Immunosuppressive effect of a new drug, FTY720, on lymphocyte responses in vitro and cardiac allograft survival in rats.
Suzuki
S
S
Department of Experimental Surgery and Bioengineering, National Children's Medical Research Center, Tokyo, Japan.
Enosawa
S
S
Kakefuda
T
T
Li
X K
XK
Mitsusada
M
M
Takahara
S
S
Amemiya
H
H
D000818:Animals; D004306:Dose-Response Relationship, Immunologic; D000068876:Fingolimod Hydrochloride; D006085:Graft Survival / Q000187:drug effects; D016027:Heart Transplantation / Q000276:immunology*; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D008213:Lymphocyte Activation / Q000187:drug effects; D008214:Lymphocytes / Q000187:drug effects* / Q000276:immunology*; D008297:Male; D011409:Propylene Glycols / Q000494:pharmacology*; D051381:Rats; D011912:Rats, Inbred ACI; D011919:Rats, Inbred Strains; D013110:Sphingosine / Q000031:analogs & derivatives; D014184:Transplantation, Homologous / Q000276:immunology
D007166:Immunosuppressive Agents; D011409:Propylene Glycols; D000068876:Fingolimod Hydrochloride; D013110:Sphingosine