Division of the human claustrum according to its architectonics and morphometric parameters.
The topography and cytoarchitectonics of the claustrum as well as morphometric parameters of its neurons were studied in 10 human brains obtained from patients without any detectable neuropathological changes. We distinguished four parts of the claustrum: dorsal, orbital, temporal and paraamygdalar. The dorsal and orbital parts contain larger cells, than those of the temporal and paraamygdalar parts, although these differences were statistically non significant. The highest neuronal density was observed in the paraamygdalar part. The nucleus and nucleus@cell body area ratio was significantly smaller in the dorsal part than in other parts of the claustrum. We described three types of neurons in the claustrum: (1) medium-sized either fusiform or triangular cells with darkly stained cytoplasm; they predominate in the dorsal and temporal parts, (2) medium-sized as well as large cells, either multipolar or pyramidal-like with lightly stained cytoplasm; they are most numerous in the orbital and paraamygdalar parts, (3) small, multipolar or oval neurons with darkly stained ring of cytoplasm; these types of neurons are uniformly distributed throughout all parts of the claustrum. The subdivision of the human claustrum is in accordance with our observations that each of these parts possesses connections with different cortical regions.
Department of Anatomy and Neurobiology, Medical University, Gdansk.
J
J
Moryś
B
B
Berdel
B
B
Maciejewska
M
M
Sadowski
M
M
Sidorowicz
J
J
Kowiañska
O
O
Narkiewicz
D001479:Basal Ganglia / Q000033:anatomy & histology* / Q000166:cytology; D001921:Brain / Q000033:anatomy & histology; D006801:Humans; D009474:Neurons / Q000166:cytology*