[Malabsorption syndrome due to membrane transporter abnormality in absorptive epithelial cells].
Pathogenesis, clinical features and diagnosis of malabsorption syndrome caused by membrane transporter abnormality of absorptive epithelial cells, such as glucose-galactose malabsorption or inherited amino acid transporter abnormality, are reviewed in this paper. It is rare for us to examine the patients with these diseases, but they are important for study of mechanisms of membrane digestion and membrane transporter in absorptive epithelial cells. Recent advances in molecular biology or genetics have made us details for the etiology of these diseases and may result in the development for new therapy.
Bamba
T
T
Second Department of Internal Medicine, Shiga University of Medical Science, Japan.
Sasaki
M
M
D002241:Carbohydrates; D002352:Carrier Proteins; D004063:Digestion; D004847:Epithelial Cells; D004848:Epithelium / Q000378:metabolism; D005223:Fats; D006801:Humans; D007408:Intestinal Absorption; D007421:Intestine, Small / Q000378:metabolism; D008286:Malabsorption Syndromes / Q000209:etiology*; D008871:Microvilli / Q000378:metabolism; D011506:Proteins
D002241:Carbohydrates; D002352:Carrier Proteins; D005223:Fats; D011506:Proteins