Assessment of changes in liver blood flow after food intake--comparison of ICG clearance and echo-Doppler.
Echo-Doppler measurements of portal venous blood flow in intrahepatic branches and indocyanine green (ICG) clearance after continuous i.v. infusion as measure for liver blood flow were compared to evaluate the increase in splanchnic blood flow after food intake. It was shown that both methods assessed the changes in flow in a similar manner. Changes in blood flow in intrahepatic portal vein branches measured with echo-Doppler adequately predicted the change in ICG concentrations. Hence, echo-Doppler measurements of hepatic portal blood flow in intrahepatic branches can be used to estimate changes in total liver blood flow.
Centre for Human Drug Research, Leiden, The Netherlands.
J
J
Burggraaf
H C
HC
Schoemaker
A F
AF
Cohen
D006801:Humans; D007208:Indocyanine Green / Q000493:pharmacokinetics*; D008099:Liver / Q000098:blood supply* / Q000000981:diagnostic imaging; D008297:Male; D019518:Postprandial Period; D012039:Regional Blood Flow; D014463:Ultrasonography
D007208:Indocyanine Green