Variant (8;22) translocation in lymphoblastic lymphoma.
Occasional cases with the chromosomal translocations that juxtapose the c-myc oncogene to Ig genes have been reported in large cell, small lymphocytic, immunoblastic, and follicular lymphomas. In this report, we present a 20 year-old female with lymphoblastic lymphoma of B-cell type and a translocation t(8;22), in which cytogenetic, immunologic, and molecular studies were performed. To the best of our knowledge this is the first report of this association.
Departmento de Genetica, Academia Nacional de Medicina, Buenos Aires, Argentina.
I
I
Slavutsky
G
G
Andreoli
M
M
Gutierrez
M
M
Narbaitz
G
G
Lucero
M
M
Eppinger
D000328:Adult; D002892:Chromosomes, Human, Pair 22; D002898:Chromosomes, Human, Pair 8; D004273:DNA, Neoplasm / Q000032:analysis / Q000235:genetics; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D007621:Karyotyping; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics* / Q000276:immunology / Q000473:pathology; D014178:Translocation, Genetic
D004273:DNA, Neoplasm