Spontaneous and evoked dysesthesias observed in the rat after spinal cordotomies.
Thirty-six rats have received surgical spinal cord lesions, 7 at a thoracic and 29 at a cervical level. More than 70% of rats with lesions which involved the lateral column (spinothalamic tract) developed spontaneous dysesthesias in the contralateral limb. Only high cervical (C1-C2) lateral column lesions were followed frequently by forelimb signs. Lesions restricted to the dorsal columns were not followed by dysesthesias.
Division of Neurosurgery, Duke University Medical Center, Durham, N.C., USA.
J
J
Ovelmen-Levitt
J
J
Gorecki
K T
KT
Nguyen
B
B
Iskandar
B S
BS
Nashold
D000818:Animals; D001522:Behavior, Animal; D003714:Denervation; D005121:Extremities / Q000503:physiopathology; D005260:Female; D007839:Functional Laterality; D009333:Neck; D010146:Pain / Q000503:physiopathology; D011183:Postoperative Complications; D051381:Rats; D017207:Rats, Sprague-Dawley; D012678:Sensation Disorders / Q000209:etiology* / Q000503:physiopathology / Q000523:psychology; D013116:Spinal Cord / Q000601:surgery*; D013909:Thorax