28833, a selective kynurenine 3-hydroxylase inhibitor. Effects on the kynurenine pathway metabolites in the gerbil.
Pharmacia, R&D CNS, Nerviano Milano, Italy.
M
M
Cini
R
R
Bormetti
M
M
Marconi
A
A
Molinari
O
O
Veneroni
M
M
Varasi
R
R
Schwarcz
C
C
Speciale
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism*; D002087:Butyrates / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005260:Female; D005849:Gerbillinae; D007736:Kynurenic Acid / Q000097:blood / Q000378:metabolism*; D007737:Kynurenine / Q000097:blood / Q000378:metabolism*; D050601:Kynurenine 3-Monooxygenase; D008297:Male; D006899:Mixed Function Oxygenases / Q000037:antagonists & inhibitors*; D051381:Rats; D017207:Rats, Sprague-Dawley
D002087:Butyrates; D004791:Enzyme Inhibitors; C104254:FCE 28833; D007737:Kynurenine; D006899:Mixed Function Oxygenases; D050601:Kynurenine 3-Monooxygenase; D007736:Kynurenic Acid