Pregnancy occurring during complete cytogenetic response after interferon therapy in chronic myeloid leukaemia.
A 25 year old woman with chronic myelogenous leukaemia was treated for 27 months with alpha-interferon, leading to complete haematological and cytogenetic remission. One year after interruption of treatment, she became pregnant and delivered a healthy full term infant. This case provides further evidence in support of the safety of alpha-interferon with respect to the fertility of women of childbearing age.
Service d'Hematologie, Hopital Saint Louis, Paris, France.
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L
Longree
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P
Pautier
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F
Guilhot
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P
Brice
D000328:Adult; D005260:Female; D006801:Humans; D007370:Interferon Type I / Q000627:therapeutic use*; D007621:Karyotyping; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy* / Q000235:genetics; D011247:Pregnancy; D011256:Pregnancy Outcome; D011994:Recombinant Proteins; D012074:Remission Induction / Q000379:methods
D007370:Interferon Type I; D011994:Recombinant Proteins