Variant (8;22) translocation in lymphoblastic lymphoma.
Occasional cases with the chromosomal translocations that juxtapose the c-myc oncogene to Ig genes have been reported in large cell, small lymphocytic, immunoblastic, and follicular lymphomas. In this report, we present a 20 year-old female with lymphoblastic lymphoma of B-cell type and a translocation t(8;22), in which cytogenetic, immunologic, and molecular studies were performed. To the best of our knowledge this is the first report of this association.
Slavutsky
I
I
Departmento de Genetica, Academia Nacional de Medicina, Buenos Aires, Argentina.
Andreoli
G
G
Gutierrez
M
M
Narbaitz
M
M
Lucero
G
G
Eppinger
M
M
D000328:Adult; D002892:Chromosomes, Human, Pair 22; D002898:Chromosomes, Human, Pair 8; D004273:DNA, Neoplasm / Q000032:analysis / Q000235:genetics; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D007621:Karyotyping; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics* / Q000276:immunology / Q000473:pathology; D014178:Translocation, Genetic
D004273:DNA, Neoplasm