Von Willebrand factor in patients evolving Q-wave versus non-Q-wave acute myocardial infarction.
We assessed the changes in plasma von Willebrand factor level concentration in 10 patients with Q-myocardial infarction and in six patients with non-Q-myocardial infarction who did not receive thrombolytic treatment. Concentrations of von Willebrand factor antigen were measured by an enzyme-linked immunoassay method in plasma samples obtained twice daily for 4 consecutive days. In patients with Q-wave myocardial infarction, a significant rise in von Willebrand factor antigen levels (P < 0.05) occurred after admission and persisted for 3 days. No significant changes were found in plasma concentration of fibrinogen. In conclusion, von Willebrand factor antigen levels were greater in patients with Q-wave compared to patients with non-Q-wave myocardial infarction.
Cardiology Unit, Hippokration Hospital, Athens University Medical School, Greece.
D
D
Tousoulis
C
C
Tentolouris
E
E
Bosinakou
T
T
Apostolopoulos
M
M
Kyriakides
P
P
Toutouzas
D000368:Aged; D000704:Analysis of Variance; D015415:Biomarkers; D004562:Electrocardiography; D005260:Female; D005340:Fibrinogen / Q000378:metabolism; D005342:Fibrinolysis / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood*; D015539:Platelet Activation / Q000502:physiology; D014841:von Willebrand Factor / Q000378:metabolism*
D015415:Biomarkers; D014841:von Willebrand Factor; D005340:Fibrinogen