Keratoconus in two pairs of identical twins.
We studied two sets of identical twins with keratoconus. The first 21-year-old pair had bilateral fully developed keratoconus and the second 35-year-old pair presented with early bilateral keratoconus detected by videokeratography. To our knowledge, these are the seventh and eighth sets of identical twins with keratoconus reported in the literature. They support the evidence of heredity as a factor in the etiology of keratoconus. Videokeratography proved to be a valuable adjunct for the detection of early keratoconus in a cornea with normal slit-lamp microscopy and photokeratoscopy results. Radial keratotomy in one eye produced an unstable refraction.
Department of Ophthalmology, Emory Eye Center, Atlanta, Georgia 30322, USA.
S J
SJ
Bechara
G O
GO
Waring
M S
MS
Insler
D000328:Adult; D004200:Diseases in Twins / Q000175:diagnosis / Q000235:genetics*; D005260:Female; D006801:Humans; D007640:Keratoconus / Q000175:diagnosis*; D014430:Twins, Monozygotic