Neuropeptide Y in hamster limbic nuclei: lack of colocalization with substance P.
The medial nucleus of the amygdala (Me), bed nucleus of the stria terminalis (BNST), and medial preoptic area (MPOA) regulate copulation in the male hamster. The present study identified neuropeptide Y-immunoreactive (NPY-IR) neurons in the BNST and Me with the greatest concentration in the posteromedial and posteriordorsal subdivisions of these nuclei, respectively. NPY-IR filters are found in all three nuclei with dense plexi of NPY-IR varicosities in the most medial subdivisions. Substance P neurons are also densely concentrated in the posterior BNST and Me; however, no neurons contained both peptides. Thus, NPY and substance P neurons comprise two distinct populations within the BNST and Me of the hamster.
Department of Biological Sciences, Rutgers University, Newark, NJ 07102, USA.
L F
LF
Burroughs
J M
JM
Fiber
J M
JM
Swann
D000679:Amygdala / Q000737:chemistry; D000818:Animals; D003307:Copulation / Q000502:physiology; D006224:Cricetinae; D007150:Immunohistochemistry; D008032:Limbic System / Q000737:chemistry*; D008297:Male; D008647:Mesocricetus; D009474:Neurons / Q000737:chemistry*; D009478:Neuropeptide Y / Q000302:isolation & purification*; D011301:Preoptic Area / Q000737:chemistry; D013373:Substance P / Q000302:isolation & purification*; D013787:Thalamic Nuclei / Q000737:chemistry; D014018:Tissue Distribution
D009478:Neuropeptide Y; D013373:Substance P