Neuroendocrine carcinoma of the larynx.
Neuroendocrine carcinomas (NEC) of the larynx are rare. The key to diagnosis is therefore an increased awareness of such lesions amongst otolaryngologists and pathologists. A precise histological diagnosis is crucial, as the management is different for each NEC sub-type. Advances in immunohistochemistry have been a great help in this respect. We report a typical case of large cell NEC (atypical carcinoid) and highlight the clinical pointers to the histological diagnosis.
University Department of Otolaryngology, University of Manchester Medical School, UK.
C
C
Hartley
A R
AR
Birzgalis
T J
TJ
Lyons
W T
WT
Farrington
D018278:Carcinoma, Neuroendocrine / Q000145:classification / Q000473:pathology* / Q000556:secondary / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000628:therapy; D007830:Larynx / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000556:secondary