Metastatic skin cancer; a case with signet ring cell histology.
We report a 64-year-old Japanese man who developed metastatic skin cancer, in the form of 1-3 cm diameter dome-shaped tumours on his face and head. Histopathological examination demonstrated diastase-resistant periodic acid--Schiff and Alcian blue-positive signet ring cells, suggesting gastric carcinoma. Immunohistochemical staining showed that these cells were positive for carbohydrate antigen CA19-9.
Department of Dermatology, Kumamoto University School of Medicine, Japan.
Y
Y
Inoue
M
M
Johno
K
K
Kayashima
H
H
Kako
M
M
Ogawa
T
T
Ono
D000951:Antigens, Neoplasm / Q000032:analysis; D018395:CA-19-9 Antigen / Q000032:analysis; D018279:Carcinoma, Signet Ring Cell / Q000556:secondary* / Q000648:ultrastructure; D006801:Humans; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000556:secondary* / Q000648:ultrastructure; D013274:Stomach Neoplasms / Q000473:pathology
D000951:Antigens, Neoplasm; D018395:CA-19-9 Antigen