Systemic administration of kainate induces marked increases of endogenous kynurenate in various brain regions and plasma of rats.
Department of Pharmacology, Toxicology, and Pharmacy, School of Veterinary Medicine, Hannover, Germany.
H
H
Baran
M
M
Gramer
D
D
Hönack
W
W
Löscher
D000818:Animals; D001921:Brain / Q000187:drug effects / Q000378:metabolism* / Q000473:pathology; D004833:Epilepsy, Temporal Lobe / Q000139:chemically induced / Q000378:metabolism* / Q000503:physiopathology; D018690:Excitatory Amino Acid Agonists / Q000633:toxicity*; D005260:Female; D007608:Kainic Acid / Q000633:toxicity*; D007736:Kynurenic Acid / Q000097:blood / Q000378:metabolism*; D009928:Organ Specificity; D051381:Rats; D017208:Rats, Wistar
D018690:Excitatory Amino Acid Agonists; D007736:Kynurenic Acid; D007608:Kainic Acid