Thermal inactivation of bovine immunodeficiency virus.
Cell-associated bovine immunodeficiency virus (BIV) and cell-free BIV were subjected to increasing temperatures, including pasteurization conditions. To determine the effect of heat treatment on BIV viability, reverse transcriptase activity and infectivity of the heat-treated virus were assessed. BIV was inactivated by heating to 47 degrees C for 30 min and by low- and high-temperature pasteurization conditions.
Moore
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Department of biological Sciences, Mississippi State University, Mississippi 39762, USA.
Keil
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Coats
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D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000517:prevention & control; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral; D006358:Hot Temperature; D016087:Immunodeficiency Virus, Bovine / Q000201:enzymology / Q000472:pathogenicity; D016180:Lentivirus Infections / Q000517:prevention & control / Q000662:veterinary; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism
D012194:RNA-Directed DNA Polymerase