Structure-based drug design.
The three-dimensional structures of more than 4,000 macromolecules have already been solved, and the number will continue to increase steadily. Many of these macromolecules are important drug targets and it is now possible to use the knowledge of their three-dimensional structure as a good basis for drug design.
Blundell
T L
TL
Department of Biochemistry, University of Cambridge, UK.
D003196:Computer Graphics; D015195:Drug Design; D005544:Forecasting; D008958:Models, Molecular; D008968:Molecular Conformation; D013329:Structure-Activity Relationship