Postpneumonectomy bronchopleural fistula after sutured bronchial closure: incidence, risk factors, and management.
OBJECTIVE
Postpneumonectomy bronchopleural fistula remains a morbid complication after pneumonectomy. The incidence, risk factors, and management of postpneumonectomy bronchopleural fistula were evaluated in 256 consecutive patients who underwent pneumonectomy with a standardized suture closure of the bronchus.


METHODS
Pneumonectomy was performed for lung cancer in 198 cases, for other malignancy in 20 cases, and for benign causes in 38 cases. The bronchial stump was closed with interrupted simple sutures to emphasize a long, membranous wall flap. All stumps were covered by autologous tissue.


RESULTS
The incidence of postpneumonectomy bronchopleural fistula was 3.1%. Risk factors for bronchopleural fistula were the need for postoperative ventilation (p = 0.0001) and right pneumonectomy (p = 0.04). Five patients had bronchopleural fistulas as a result of pulmonary complications necessitating ventilation; the cause in the remaining three cases appeared to be technical. Reclosure was successful in five cases (mean postoperative day 12); in one case a pinhole fistula was healed by drainage alone. Two (25%) of the eight patients who had bronchopleural fistulas died.


CONCLUSIONS
Careful, sutured closure of the main bronchus with a tissue buttress after pneumonectomy yields excellent results. The most significant risk factor for bronchopleural fistula is a pulmonary complication necessitating ventilation. Contrary to previous reports, reclosure is usually successful even if performed late.
General Thoracic Surgical Unit, Massachusetts General Hospital, Boston 02114, USA.
C D
CD
Wright
J C
JC
Wain
D J
DJ
Mathisen
H C
HC
Grillo
D001983:Bronchial Fistula / Q000209:etiology*; D006801:Humans; D008171:Lung Diseases / Q000601:surgery; D008175:Lung Neoplasms / Q000601:surgery; D010995:Pleural Diseases / Q000209:etiology*; D011013:Pneumonectomy; D011183:Postoperative Complications; D012121:Respiration, Artificial; D012307:Risk Factors; D013536:Suture Techniques