DES awareness and exposure: the 1994 California Behavioral Risk Factor Survey.
BACKGROUND
Diethylstilbestrol (DES), a drug used in millions of pregnancies between 1938 and 1971, is the first known human transplacental carcinogen. DES is also associated with other serious health problems for those exposed to it either in utero or while pregnant; however, many men and women are unaware of their exposure or how to protect their health. This first population-based study of DES awareness is part of the National Cancer Instututes's National DES Education Program.


METHODS
In 1994, 2,077 women and 1,625 men 23 years of age and over responded to the California Behavioral Risk Factor Survey (BRFS). These subjects were either born during the years DES was in use (men and women 23-53 years old in 1994) or could have been pregnant during those years (women 39 years or older).


RESULTS
Analyses weighted to the 1994 California age and ethnicity distribution indicate that only 43% of women and 22% of men had over heard of DES (P < .001). Although 44% of Caucasians had heard of DES, only 10% of Hispanics, 27% of African Americans, and 24% of other races had heard of DES. Within each group, women had heard of DES significantly more often than men. Only 17% of women and 5% of men had ever tried to confirm whether they were exposed to DES in utero, and 8% of women whether they were exposed while pregnant.


CONCLUSIONS
Given the serious health consequences of DES exposure and available prevention strategies, this lack of awareness warrants an immediate educational effort.
Department of Family and Preventive Medicine, University of California, San Diego, USA.
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Wingard
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Cohn
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Helmrich
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Edelstein
D000328:Adult; D002273:Carcinogens / Q000633:toxicity*; D004054:Diethylstilbestrol / Q000633:toxicity*; D005006:Ethnicity; D005260:Female; D005333:Fetus / Q000187:drug effects*; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects
D002273:Carcinogens; D004054:Diethylstilbestrol