The hands in Saethre-Chotzen syndrome.
The hand radiographs of fifteen patients with a diagnosis of Saethre-Chotzen syndrome were reviewed by a radiologist with an interest in skeletal dysplasia along with the craniofacial team. Eleven patients exhibited a range of bone abnormalities of the following sites: thumbs, fingers, metacarpals, and the radius. The epiphysis of the distal phalanx of the thumb was most commonly involved site with 7 of the 15 patients affected. In addition to the structural abnormalities all cases before puberty (14 out of 15 patients in this series) showed variable delay of the bone age.
Anderson
P J
PJ
Department of Craniofacial Surgery, Great Ormond Street Hospital, London, United Kingdom.
Hall
C M
CM
Evans
R D
RD
Hayward
R D
RD
Jones
B M
BM
D000168:Acrocephalosyndactylia / Q000000981:diagnostic imaging*; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006228:Hand Deformities, Congenital / Q000000981:diagnostic imaging*; D006801:Humans; D007223:Infant; D008297:Male; D011859:Radiography