Anthelmintic resistant nematodes in goats in The Netherlands.
A suspected case of anthelmintic resistance on a farm with Angora and Anglo-Nubian goats was confirmed in a controlled test. Twelve lambs of sheep were infected with larvae cultured from faeces of the goats. The lambs were allocated to four groups: untreated controls and lambs treated 21 days after infection with 5 mg kg-1 oxfendazole, 0.2 mg kg-1 ivermectin or 7.5 mg kg-1 levamisole. The lambs were slaughtered 1 week later and post-mortem worm counts were performed. Benzimidazole resistance was found in Haemonchus contortus, Teladorsagia circumcincta, Cooperia curticei and Trichostrongylus colubriformis with the efficacy of oxfendazole being 68%, 31%, 21% and 48% respectively. No resistance was found against levamisole or ivermectin.
Borgsteede
F H
FH
DLO-Institute for Animal Science and Health, Lelystad, Netherlands.
Pekelder
J J
JJ
Dercksen
D P
DP
D000018:Abomasum / Q000469:parasitology; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D001562:Benzimidazoles / Q000627:therapeutic use*; D004351:Drug Resistance; D005243:Feces / Q000469:parasitology; D015511:Goat Diseases; D006041:Goats; D007421:Intestine, Small / Q000469:parasitology; D007559:Ivermectin / Q000627:therapeutic use*; D007814:Larva; D007978:Levamisole / Q000627:therapeutic use*; D009348:Nematoda / Q000254:growth & development / Q000302:isolation & purification*; D009349:Nematode Infections / Q000188:drug therapy / Q000503:physiopathology / Q000662:veterinary*; D009426:Netherlands
D000871:Anthelmintics; D001562:Benzimidazoles; D007978:Levamisole; D007559:Ivermectin; C011030:oxfendazole