Duration of antibiotic treatment in surgical infections of the abdomen. The future: randomised prospective studies.
The important questions are: what is the most efficient, least costly, and least hazardous way of providing antimicrobial therapy to postoperative patients? These questions, and the answers, are integral to the practice of medicine. I discuss a few pitfalls associated with antibiotic studies and suggest potential solutions. I urge doctors interested in these problems to focus on establishing the hospital systems needed to provide continuous feedback, rather than sporadic information driven by collegial requests.
Department of Surgery, University of Cincinnati College of Medicine, OH 4526-0558 , USA. joseph.solomkin@uc.edu
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Solomkin
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D006801:Humans; D015337:Multicenter Studies as Topic; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D012107:Research Design; D012307:Risk Factors
D000900:Anti-Bacterial Agents