Serious infections due to penicillin-resistant Streptococcus peneumoniae in two children with nephrotic syndrome.
Children with nephrotic syndrome are susceptible to the development of invasive bacterial infections, particularly those caused by Streptococcus peneumoniae. Recently, penicillin-resistant pneumococcal infections in children have occurred in increased frequency in some regions. We have seen two children with nephrotic syndrome who developed penicillin-resistant pneumococcal bacteremia and/or peritonitis. A change in the initial therapy from penicillin in the usual dose in these patients must be considered.
Ilyas
M
M
Department of Pediatrics, University of Tennessee, Memphis, USA.
Roy
S
S
Abbasi
S
S
Leggiadro
R J
RJ
English
B K
BK
Wyatt
R J
RJ
D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009404:Nephrotic Syndrome / Q000150:complications*; D010403:Penicillin Resistance; D011008:Pneumococcal Infections / Q000188:drug therapy / Q000209:etiology*