Dexamethasone in adenotonsillectomy.
Edema contributes substantially to the postoperative discomfort and morbidity of adenotonsillectomy. In a double-blind study, 58 children undergoing adenotonsillectomy were given a single intraoperative dose of either dexamethasone or saline. The steroid markedly affected the postoperative course in the first day after surgery. According to parental reports, the percentage of patients vomiting was reduced from 48 to 4%. Severe throat pain was reported in 57% of controls and only 20% of dexamethasone patients. Twice as many steroid patients as controls tolerated some soft food on the first postoperative day. It appears that dexamethasone can greatly improve patient diet and comfort after adenotonsillectomy.
Division of Otolaryngology, Children's Hospital of Philadelphia, PA 19104, USA.
L W
LW
Tom
J J
JJ
Templeton
M E
ME
Thompson
R R
RR
Marsh
D000233:Adenoidectomy / Q000009:adverse effects; D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003907:Dexamethasone / Q000008:administration & dosage / Q000627:therapeutic use*; D004311:Double-Blind Method; D004435:Eating; D004487:Edema / Q000517:prevention & control; D005502:Food; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D007275:Injections, Intravenous; D007430:Intraoperative Care; D010149:Postoperative Pain / Q000517:prevention & control; D010612:Pharyngitis / Q000517:prevention & control; D011183:Postoperative Complications / Q000517:prevention & control; D012965:Sodium Chloride; D014068:Tonsillectomy / Q000009:adverse effects; D014839:Vomiting / Q000517:prevention & control
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D012965:Sodium Chloride; D003907:Dexamethasone