Follow-up study of biological parameters in elderly institutionalized patients more than one year after discontinuation of calcium-vitamin D supplementation.
Laboratory tests were done 15 to 19 months after completion of a six-month clinical trial of oral supplementation with 1 g elemental calcium and 800 IU vitamin D per day in elderly institutionalized patients. Serum 25-OH-vitamin D and intact parathyroid hormone levels returned to normal during the trial, indicating efficacy of the supplementation in correcting the vitamin D deficiency and secondary hyperparathyroidism present before the trial. Data were available before, during, immediately after and 15 to 19 months after the trial in 37 patients. Recurrence of the vitamin D deficiency was observed after discontinuation of the supplementation.
Rheumatology Department, Amiens Teaching Hospital, France.
J L
JL
Sebert
P
P
Fardellone
M
M
Maamer
F
F
Agbomson
M
M
Brazier
M
M
Garabedian
D000284:Administration, Oral; D000368:Aged; D000369:Aged, 80 and over; D000704:Analysis of Variance; D002118:Calcium / Q000627:therapeutic use*; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D010281:Parathyroid Hormone / Q000097:blood; D012866:Skilled Nursing Facilities; D016896:Treatment Outcome; D014807:Vitamin D / Q000097:blood / Q000627:therapeutic use*; D014808:Vitamin D Deficiency / Q000188:drug therapy*
D010281:Parathyroid Hormone; D014807:Vitamin D; D002118:Calcium