[Comparison of analgesic effect of lidocaine tape versus eutectic mixture of lidocaine and tetracaine during infiltration of local anesthetics before epidural block].
We compared analgesic effects of a lidocaine tape (Penles) and the eutectic mixture of lidocaine and tetracaine (LT ointment) during local infiltration before epidural block. Ninety-six patients were randomly assigned to 3 groups. In groups 1 and 2, lidocaine tape was applied on the skin of the epidural puncture site 30-60 min before epidural block. In group 3, 1 g of LT ointment was applied on the same place 1-2 h before block. Additionally, patients in groups 2 and 3 were medicated intramuscularly with midazolam 5 mg. Although no significant difference in pain relief in 5 pin prick tests was observed among the three groups, there was a significantly greater decrease in the pain score during the infiltration of local anesthetics in groups 1 and 2, compared with group 3. There was no significant difference in the pain score between groups 1 and 2. We concluded that lidocaine tape is more useful than LT ointment in decreasing pain of local infiltration anesthesia, and midazolam did not exert any supplementary analgesic effect.
Department of Anesthesia, Kawanishi City Hospital.
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T
Kawano
S
S
Shiraishi
T
T
Nakamura
H
H
Yokoo
M
M
Takasaki
D000287:Administration, Topical; D000328:Adult; D000767:Anesthesia, Epidural; D000772:Anesthesia, Local / Q000009:adverse effects*; D019162:Anesthetics, Combined; D000779:Anesthetics, Local; D014151:Anti-Anxiety Agents; D004304:Dosage Forms; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008012:Lidocaine; D008297:Male; D008874:Midazolam; D008875:Middle Aged; D010146:Pain / Q000209:etiology* / Q000517:prevention & control*; D011229:Preanesthetic Medication; D013129:Spinal Puncture / Q000009:adverse effects; D013748:Tetracaine
D019162:Anesthetics, Combined; D000779:Anesthetics, Local; D014151:Anti-Anxiety Agents; D004304:Dosage Forms; D013748:Tetracaine; D008012:Lidocaine; D008874:Midazolam