Cerebral oligodendrogliomas in children: an analysis of 15 cases.
The cases of 15 children operated on for cerebral pure oligodendroglioma were studied. Two groups of children were distinguished. Group I children presented with epilepsy (7 cases); their tumor was histologically benign in all cases. These children are all alive after a median follow-up of 72 months: however, 2 of them presented with a local recurrence, which was operated on, and are actually disease-free. Group 2 children presented with intracranial hypertension (8 cases); the tumor was anaplastic in 7 cases. Despite postoperative radiotherapy and chemotherapy 6 children died; their median survival time was 17 months. The present series shows the existence of a clear correlation between clinical presentation, histological grading and survival in childhood cerebral oligodendrogliomas.
Service de Neurochirurgie Pédiatrique, Hôpital Pierre Wertheimer, Lyon, France.
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T
Rizk
C
C
Mottolèse
E
E
Bouffet
A
A
Jouvet
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J
Guyotat
P
P
Bret
C
C
Lapras
D000293:Adolescent; D001932:Brain Neoplasms / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D009837:Oligodendroglioma / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D016019:Survival Analysis; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome