[Improvement of thrombocytopenia by administration of M-CSF in a patient with relapsed Philadelphia chromosome-positive acute lymphoblastic leukemia].
A 55-year old male, diagnosed as Ph1 (+) ALL in July 1992, subsequently achieved complete remission. However, he was admitted again in November 1993 because of relapse. Although blasts in bone marrow decreased following chemotherapy and G-CSF administration, thromocytopenia remained, and he needed platelet transfusions every other day. After he began receiving M-CSF, the platelet count increased and platelet transfusions became unnecessary. M-CSF may be useful for thrombocytopenia after chemotherapy in Ph1 (+) ALL.
Second Department of Internal Medicine, Tottori University School of Medicine.
A
A
Endo
F
F
Tajima
T
T
Kawatani
H
H
Kawasaki
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016179:Granulocyte Colony-Stimulating Factor / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D016173:Macrophage Colony-Stimulating Factor / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy*; D012008:Recurrence; D013921:Thrombocytopenia / Q000209:etiology* / Q000628:therapy*
D016179:Granulocyte Colony-Stimulating Factor; D016173:Macrophage Colony-Stimulating Factor