Sparteine metabolism in a Nigerian population.
The oxidative metabolism of sparteine has been investigated in a Nigerian population. The distribution of metabolic capacities was shown to be skewed with two subjects (2/97, 2.1%) being relatively deficient in their ability to produce the dehydrometabolites. These observations afford evidence that sparteine oxidation is under polymorphic control in Nigerians.
Imperial College School of Medicine at St. Mary's, London, U.K.
J C
JC
Ritchie
S C
SC
Mitchell
R L
RL
Smith
D000328:Adult; D002855:Chromatography, Thin Layer; D005260:Female; D006801:Humans; D008297:Male; D009549:Nigeria; D010084:Oxidation-Reduction; D010783:Photometry; D011110:Polymorphism, Genetic; D013034:Sparteine / Q000031:analogs & derivatives / Q000378:metabolism* / Q000652:urine
D013034:Sparteine; C044694:2-dehydrosparteine