Intravenous gammaglobulin therapy of Satoyoshi syndrome.
Satoyoshi syndrome is a very rare disease of unknown etiology, characterized by intermittent painful muscle spasms, alopecia, multiple epiphyseal changes, diarrhea and endocrine disorders. We administered intravenous gammaglobulin to a 7-year-old girl with Satoyoshi syndrome. Frequency of muscle spasms and the titers of antinuclear antibody and anti-DNA antibody decreased. This is the first report of gammaglobulin therapy of Satoyoshi syndrome. We suggest that this illness could be related to an autoimmune mechanism.
Arita
J
J
Division of Neurology, Saitama Children's Medical Center, Japan.
Hamano
S
S
Nara
T
T
Maekawa
K
K
D000505:Alopecia / Q000628:therapy*; D002357:Cartilage Diseases / Q000473:pathology / Q000628:therapy*; D002648:Child; D005260:Female; D006132:Growth Plate / Q000473:pathology; D006801:Humans; D007167:Immunotherapy; D008279:Magnetic Resonance Imaging; D009128:Muscle Spasticity / Q000473:pathology / Q000628:therapy*; D013577:Syndrome; D005719:gamma-Globulins / Q000008:administration & dosage
D005719:gamma-Globulins