New preparation of triterpenoid-3-sulfates by the use of SO3-DMSO complex.
The use of sulfur trioxide-dimethyl sulfoxide (SO3-DMSO) complex in dimethyl sulfoxide solution for the preparation of triterpenoid-3-sulfates with heavily quantitative yields has been described. The high reagent selectivity for equatorial 3-hydroxy groups in presence of an axial 16-hydroxy group was demonstrated.
Grishkovets
V I
VI
Department of Organic Chemistry, Simferopol State University, Ukraine.
Kondratenko
A E
AE
Chirva VYa
D004121:Dimethyl Sulfoxide; D009828:Oleanolic Acid / Q000031:analogs & derivatives / Q000138:chemical synthesis; D013431:Sulfates / Q000138:chemical synthesis*; D013461:Sulfur Oxides; D014315:Triterpenes / Q000138:chemical synthesis*
D013431:Sulfates; D013461:Sulfur Oxides; D014315:Triterpenes; D009828:Oleanolic Acid; C011118:sulfur trioxide; C022999:echinocystic acid; D004121:Dimethyl Sulfoxide