Intestinal water and electrolyte absorption and secretion.
Diarrhea is a frequent complication of small bowel transplantation in patients and experimental models. Although there are many potential causes, the underlying basis for most are not fully understood. Improved therapeutic approaches will come about through better understanding of mechanisms of bowel adaptation and regulation.
Department of Medicine, University of Chicago, IL 60637, USA.
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Chang
D000818:Animals; D000838:Anions / Q000378:metabolism; D001647:Bile Acids and Salts / Q000378:metabolism; D003967:Diarrhea / Q000453:epidemiology; D004573:Electrolytes / Q000378:metabolism; D006086:Graft vs Host Disease; D006706:Homeostasis; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D007408:Intestinal Absorption; D007413:Intestinal Mucosa / Q000502:physiology* / Q000637:transplantation*; D007420:Intestine, Large / Q000502:physiology; D007421:Intestine, Small / Q000502:physiology* / Q000637:transplantation*; D008208:Lymphatic System / Q000502:physiology / Q000503:physiopathology; D008286:Malabsorption Syndromes; D008954:Models, Biological; D009121:Muscle Denervation; D018482:Muscle, Skeletal / Q000502:physiology / Q000637:transplantation; D009894:Opportunistic Infections / Q000209:etiology; D011183:Postoperative Complications; D014867:Water
D000838:Anions; D001647:Bile Acids and Salts; D004573:Electrolytes; D014867:Water