Interleukin-2 associated linear IgA bullous dermatosis.
Linear IgA bullous dermatosis (LABD) in adults is characterized by subepidermal bullae associated with a linear deposition of IgA at the basement membrane zone. Its cause is unclear, although it appears to have an immune-mediated basis. The development of LABD in a cancer patient undergoing immunotherapy has been described in the French literature. We describe a similar case of LABD arising in a patient while undergoing interleukin-2 immunotherapy for renal cell carcinoma.
Tranvan
A
A
Section of Dermatology, University of Chicago Medical Center, USA.
Pezen
D S
DS
Medenica
M
M
Michelson
G C
GC
Vogelzang
N
N
Soltani
K M
KM
D000368:Aged; D006801:Humans; D007070:Immunoglobulin A / Q000378:metabolism; D007376:Interleukin-2 / Q000009:adverse effects*; D008297:Male; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000378:metabolism
D007070:Immunoglobulin A; D007376:Interleukin-2