Bipolar disorder following a stroke involving the left hemisphere.
OBJECTIVE
Post-stroke mania has rarely been noted and researched, and reported cases have mostly involved the non-dominant hemisphere. In this paper, we report a case of bipolar disorder secondary to a stroke over the dominant hemisphere.


METHODS
A 48-year-old, right-handed man had a cerebral infarct over the left temporal region. He became depressed after the stroke, and 4 months later developed a manic episode.


METHODS
The patient was treated with haloperidol and lorazepam.


RESULTS
The symptoms subsided within 2 months after treatment.


CONCLUSIONS
It is premature to consider mania to be a syndrome of the right, or non-dominant, hemisphere. We suggest that further study focusing on specific anatomical regions, rather than laterality, will help to elucidate the interrelationship between mood and brain function.
Department of Psychiatry, Chang-Gung Medical College and Chang-Gung Memorial Hospital, Taoyuan, Taiwan, ROC.
C Y
CY
Liu
S J
SJ
Wang
J L
JL
Fuh
Y Y
YY
Yang
H C
HC
Liu
D001714:Bipolar Disorder / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D002544:Cerebral Infarction / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D004292:Dominance, Cerebral / Q000502:physiology*; D004359:Drug Therapy, Combination; D006220:Haloperidol / Q000008:administration & dosage; D006801:Humans; D008140:Lorazepam / Q000008:administration & dosage; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D009460:Neurologic Examination / Q000187:drug effects
D006220:Haloperidol; D008140:Lorazepam