LC50 of 2-bromopropane.
LC50 of 2-bromopropane was reexamined by using the OECD guideline in ICR mouse. The mice, 3 males and 3 females, were exposed to 2-bromopropane at five different concentrations for 4 h in inhalation chambers. The exposed animals were observed for 14 days. The animals which had survived and died were counted for the LC50 determination. The LC50 was calculated by using a dose-mortality curve at a 95 percent confidence level. The LC50 was 31,171 ppm, and the lowest lethal concentration (LLC) was lower than 29,528 ppm and the lethal concentration at 100% (LC100) was higher than 32,905 ppm.
Kim
H Y
HY
Department of Industrial Toxicology, Industrial Health Research Institute Korea Industrial Safety Corporation, Bupyung-gu, Inchon, Korea.
Chung
Y H
YH
Yi
K H
KH
Kim
J G
JG
Yu
I J
IJ
D000280:Administration, Inhalation; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D006842:Hydrocarbons, Brominated / Q000633:toxicity*; D007928:Lethal Dose 50; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D012997:Solvents / Q000633:toxicity*
D006842:Hydrocarbons, Brominated; D012997:Solvents; C103736:2-bromopropane