Glutathione and glutathione delivery compounds.
Deficiency of GSH (BSO model) demonstrates the need for cellular protection from endogenous ROS. The pathology of various diseases is often associated with ROS and oxidative stress. The several methods for modulating cellular GSH levels presented in this chapter offer selective tools to study mechanisms and offer potential therapy of human diseases associated with GSH deficiency and oxidative stress.
Department of Biochemistry, Cornell University Medical College, New York, New York 10021, USA.
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Anderson
D000818:Animals; D005978:Glutathione / Q000008:administration & dosage / Q000172:deficiency / Q000378:metabolism*; D006801:Humans
D005978:Glutathione