Caries prevention: current strategies, new directions.
Despite major advances in caries prevention, a large subset of the U.S. population still needs additional control measures. In numerous other countries, needs are escalating as caries rates continue to rise. Building on current strategies and new insights into the specific mechanisms of caries initiation, researchers are creatively using a variety of new technologies, especially in molecular biology, to fashion a new generation of preventive measures.
Mandel
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Columbia University, School of Dental and Oral Surgery, New York, NY, USA.
D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D001428:Bacterial Vaccines; D003731:Dental Caries / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control*; D003733:Dental Caries Susceptibility; D003743:Dental Enamel / Q000378:metabolism; D003773:Dental Plaque / Q000517:prevention & control; D004035:Diet Therapy; D005459:Fluorides / Q000008:administration & dosage / Q000493:pharmacokinetics; D006801:Humans; D007116:Immunization, Passive; D007770:L-Lactate Dehydrogenase / Q000235:genetics; D015202:Protein Engineering; D013295:Streptococcus mutans / Q000201:enzymology / Q000235:genetics; D014089:Tooth Remineralization / Q000379:methods; D014481:United States / Q000453:epidemiology
D000891:Anti-Infective Agents, Local; D001428:Bacterial Vaccines; D007770:L-Lactate Dehydrogenase; D005459:Fluorides