Posterior routes of choroidal blood outflow in high myopia.
OBJECTIVE
A few reports in the ophthalmic literature have described choroidal blood outflow through posterior routes. Most of the patients reported were highly myopic; therefore, a correlation between such posterior routes and high myopia has been suspected. The authors examined highly myopic eyes using indocyanine green (ICG) videoangiography and investigated the prevalence and clinical significance of posterior routes in them.


METHODS
The authors examined 255 highly myopic eyes (146 patients) using ICG videoangiography. All had refractive errors greater than--8.25 diopters (D). They also examined a control group consisting of 42 eyes (26 patients) that had refractive errors within +/- 3D.


RESULTS
Of 255 highly myopic eyes, 61 (23.9%) had choroidal blood outflow through posterior routes. These routes were classified by type of vein according to its penetration site. One drained into the margin of the optic nerve head, and the other penetrated the sclera near the macula. However, only 1 of the 42 eyes (2.4%) in the control group showed choroidal outflow by a posterior route. The prevalence of posterior routes was significantly higher in the highly myopic eyes than in the control group (P < 0.05).


CONCLUSIONS
Posterior routes of choroidal blood outflow were observed in nearly 25% of highly myopic eyes. These vessels appear to be one of the major routes of posterior choroidal outflow in highly myopic eyes.
Ohno-Matsui
K
K
Department of Ophthalmology, School of Medicine, Tokyo Medical and Dental University, Japan.
Morishima
N
N
Ito
M
M
Yamashita
S
S
Tokoro
T
T
D000293:Adolescent; D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D002829:Choroid / Q000098:blood supply*; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000150:complications / Q000503:physiopathology*; D009898:Optic Disk / Q000098:blood supply; D012039:Regional Blood Flow; D012590:Sclera / Q000098:blood supply; D014680:Veins; D014792:Visual Acuity
D007208:Indocyanine Green