Formation of micronuclei and inhibition of topoisomerase II in the comet assay in mammalian cells with altered DNA methylation.
Stopper
H
H
Department of Toxicology, University of Würzburg, Germany.
Eckert
I
I
Wagener
P
P
Schulz
W A
WA
D000677:Amsacrine / Q000494:pharmacology; D000818:Animals; D001374:Azacitidine / Q000633:toxicity*; D018236:Carcinoma, Embryonal; D002454:Cell Differentiation; D019175:DNA Methylation; D004273:DNA, Neoplasm / Q000096:biosynthesis / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005020:Ethyl Methanesulfonate / Q000494:pharmacology; D017403:In Situ Hybridization; D018386:Kinetochores / Q000187:drug effects; D007940:Leukemia L5178; D008322:Mammals; D051379:Mice; D048629:Micronuclei, Chromosome-Defective / Q000187:drug effects / Q000502:physiology / Q000648:ultrastructure; D015162:Micronucleus Tests; D009153:Mutagens / Q000633:toxicity*; D059005:Topoisomerase II Inhibitors; D014407:Tumor Cells, Cultured
D004273:DNA, Neoplasm; D004791:Enzyme Inhibitors; D009153:Mutagens; D059005:Topoisomerase II Inhibitors; D000677:Amsacrine; D005020:Ethyl Methanesulfonate; D001374:Azacitidine