The t(1;12)(p36;q13) in a renal oncocytoma.
A new chromosome rearrangement, t(1;12)(p36;q13), is added to the cytogenetic changes found in renal oncocytomas. The breakpoint in 12q is cytogenetically different from those of the MAR region, and molecularly HMGIC located in 12q15 on the basis of 3' RACE experiments does not seem to be directly involved.
Center for Human Genetics, University of Leuven, Belgium.
P
P
Dal Cin
H
H
Van Poppel
R
R
Sciot
R
R
De Vos
B
B
Van Damme
L
L
Baert
H
H
Van den Berghe
D018249:Adenoma, Oxyphilic / Q000235:genetics* / Q000648:ultrastructure; D002878:Chromosomes, Human, Pair 1; D002881:Chromosomes, Human, Pair 12; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000235:genetics* / Q000648:ultrastructure; D008875:Middle Aged; D014178:Translocation, Genetic