Liver transplantation for Langerhans' cell histiocytosis--a case report and literature review.
Langerhans' cell histiocytosis (LCH) is a rare disorder of unknown etiology and pathogenesis. End-stage chronic liver disease is one presentation and orthotopic liver transplantation (OLT) has been reported in 17 cases, with variable resolution of LCH lesions postoperatively. We report a case of multisystem LCH with end-stage liver disease treated by OLT and review the overall results of OLT for children with LCH.
Liver Transplant Surgical Service and Department of Child Health, King's College Hospital, London, United Kingdom.
H V
HV
Melendez
A
A
Dhawan
G
G
Mieli-Vergani
M
M
Rela
N D
ND
Heaton
J
J
Pritchard
A
A
Mowat
D002675:Child, Preschool; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000453:epidemiology / Q000209:etiology / Q000601:surgery*; D006801:Humans; D015994:Incidence; D007223:Infant; D016031:Liver Transplantation