Radiotherapy after hyperbaric oxygenation for malignant gliomas: a pilot study.
The results of radiotherapy combined with hyperbaric oxygen in 9 patients with malignant glioma were compared with those of radiotherapy without hyperbaric O2 in 12 patients. This is the first report of a pilot study of irradiation immediately after exposure to hyperbaric O2 in humans. All patients receiving this treatment showed more than 50% regression of the tumor, and in 4 of them, the tumors disappeared completely. Only 4 out of 12 patients without hyperbaric O2 showed decreases in tumor size, and all 12 patients died within 36 months. So far, this new regimen seems to be a useful form of radiotherapy for malignant gliomas.
Department of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, Japan.
K
K
Kohshi
Y
Y
Kinoshita
H
H
Terashima
N
N
Konda
A
A
Yokota
T
T
Soejima
D000293:Adolescent; D000368:Aged; D001254:Astrocytoma / Q000532:radiotherapy*; D005260:Female; D005909:Glioblastoma / Q000532:radiotherapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D011838:Radiation-Sensitizing Agents
D011838:Radiation-Sensitizing Agents