Mechanisms of target selection by DNA-damaging chemicals: studies with enediyne anticancer drugs.
Dedon
P C
PC
Division of Toxicology, Massachusetts Institute of Technology, Cambridge 02139, USA. pcdedon@mit.edu
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D000903:Antibiotics, Antineoplastic / Q000737:chemistry / Q000494:pharmacology*; D002843:Chromatin / Q000187:drug effects; D004273:DNA, Neoplasm / Q000187:drug effects*; D053281:Enediynes; D018390:Gene Targeting; D008968:Molecular Conformation; D009153:Mutagens / Q000494:pharmacology; D010455:Peptides; D009353:Zinostatin / Q000737:chemistry / Q000494:pharmacology
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; D002843:Chromatin; D004273:DNA, Neoplasm; D053281:Enediynes; D009153:Mutagens; D010455:Peptides; C055955:calicheamicin gamma(1)I; C058024:C 1027; D009353:Zinostatin; C047543:esperamicin A1