Spontaneous decrease of a pilocytic astrocytoma in neurofibromatosis type 1.
A patient with type 1 neurofibromatosis was followed up with neuroimaging over a period of 12 years. A spontaneous decrease in the size of a histologically verified pilocytic astrocytoma was documented on serial CT and MR examinations. Subsequent studies showed the development of a lesion in the contralateral hemisphere with mass effect and contrast enhancement. Results of a biopsy disclosed normal brain tissue; follow-up imaging showed a spontaneous decrease in the size of this abnormality.
Department of Diagnostic Radiology, University of Oulu, Finland.
E L
EL
Leisti
J
J
Pyhtinen
M
M
Poyhonen
D000328:Adult; D001254:Astrocytoma / Q000175:diagnosis* / Q000473:pathology; D001706:Biopsy; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009365:Neoplasm Regression, Spontaneous; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000473:pathology; D009456:Neurofibromatosis 1 / Q000175:diagnosis* / Q000473:pathology; D014057:Tomography, X-Ray Computed