ABC transporters in Archaea: two genes encoding homologs of the nucleotide-binding components in the methanogen Methanosarcina mazei S-6.
Two genes, 5'-orfD-orfF-3', were found in the genome of the archaeon Methanosarcina mazei S-6 that encode the deduced proteins, OrfD and OrfF, with structural motifs typical of the nucleotide-binding components of the ABC-transporter systems of Bacteria and Eukarya. These motifs, and other similarities of OrfD and OrfF with bacterial and eukaryal counterparts, indicate that the two archaeal molecules belong to the ATP-binding cassette (ABC)-transporter family.
Wadsworth Center, Division of Molecular Medicine, New York State Department of Health, USA.
R J
RJ
Jovell
A J
AJ
Macario
E
E
Conway de Macario
D018528:ATP-Binding Cassette Transporters / Q000235:genetics*; D000595:Amino Acid Sequence; D019843:Archaeal Proteins; D001426:Bacterial Proteins / Q000235:genetics*; D003001:Cloning, Molecular; D018387:Codon, Initiator; D016213:Cyclins / Q000235:genetics*; D004722:Endoribonucleases; D005798:Genes, Bacterial; D017020:Methanosarcina / Q000235:genetics*; D008969:Molecular Sequence Data; D010802:Phylogeny; D014176:Protein Biosynthesis
D018528:ATP-Binding Cassette Transporters; D019843:Archaeal Proteins; D001426:Bacterial Proteins; D018387:Codon, Initiator; D016213:Cyclins; C490385:OrfD protein, archaeal; C489919:orfF protein, archaea; D004722:Endoribonucleases