title: Aspergilloma in the paracavernous region--two case reports.
abstract: A 30-year-old male and a 40-year-old female presented with Aspergillus fungal granuloma in the cerebral locations involving the gasserian-ganglion and its divisions in one case and was densely adherent to the lateral dural wall of the cavernous sinus in the other. Both patients were otherwise healthy with no evidence of immuno-suppression. The lesions resembled benign tumor on preoperative imaging and intraoperative consistency and vascularity. The lesions were successfully and completely resected. Both patients developed major cerebral arterial territory infarcts in the postoperative phase, remote from the site of operation, leading to crippling neurological deficits in one patient and death in the other. The unusual location and the unusual and similar clinical course suggests that awareness of the possibility of ischemic complications after surgical resection of intracranial aspergillomas is necessary.
authors.affiliation: Department of Neurosurgery, King Edward Memorial Hospital, Bombay, India.
authors.forename: A
authors.initials: A
authors.lastname: Goel
authors.forename: T
authors.initials: T
authors.lastname: Nadkarni
authors.forename: A P
authors.initials: AP
authors.lastname: Desai
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D001228:Aspergillosis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D002426:Cavernous Sinus; D002544:Cerebral Infarction / Q000209:etiology; D003131:Combined Modality Therapy; D003399:Craniotomy; D004660:Encephalitis / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006429:Hemiplegia / Q000209:etiology; D006801:Humans; D008297:Male; D012640:Seizures / Q000209:etiology
chemical_list: D000666:Amphotericin B