Chromatin: a sticky silence.
Recent findings indicate that heterochromatin serves as a molecular sink for factors involved in chromatin-mediated repression of gene expression; long-range interactions that position a euchromatic gene near a heterochromatin domain influence its susceptibility to transcriptional silencing.
Marcand
S
S
Laboratoire de Biologie Moléculaire et Cellulaire, l'Ecole Normale Supérieure de Lyon, UMR49 CNRS/ENS, France.
Gasser
S M
SM
Gilson
E
E
D000818:Animals; D002843:Chromatin / Q000502:physiology*; D004330:Drosophila / Q000235:genetics; D005786:Gene Expression Regulation / Q000502:physiology*; D006570:Heterochromatin / Q000502:physiology; D012441:Saccharomyces cerevisiae / Q000235:genetics; D016615:Telomere; D015534:Trans-Activators / Q000502:physiology
D002843:Chromatin; D006570:Heterochromatin; D015534:Trans-Activators