Ion channel associated proteins.
Neuronal ion channels are directly associated in vivo with a wide variety of proteins. New classes of channel-associated proteins have been identified recently, including the PSD-95/SAP90 family of channel-clustering molecules and components of the synaptic vesicle release machinery. Recent findings suggest that non-pore-forming subunits of ion channels may also have cell biological functions independent of their effects on channel electrophysiological properties.
Sheng
M
M
Howard Hughes Medical Institute, Massachusetts General Hospital, Boston 02114, USA. sheng@helix.mgh.harvard.edu
Kim
E
E
D000818:Animals; D015220:Calcium Channels / Q000502:physiology; D000076122:Disks Large Homolog 4 Protein; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D015640:Ion Channel Gating; D007473:Ion Channels / Q000494:pharmacology*; D008322:Mammals; D008565:Membrane Proteins / Q000502:physiology; D008959:Models, Neurological; D009419:Nerve Tissue Proteins / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000502:physiology; D050765:Qa-SNARE Proteins
D015220:Calcium Channels; C501444:DLG4 protein, human; D000076122:Disks Large Homolog 4 Protein; D047908:Intracellular Signaling Peptides and Proteins; D007473:Ion Channels; D008565:Membrane Proteins; D009419:Nerve Tissue Proteins; D018377:Neurotransmitter Agents; D050765:Qa-SNARE Proteins; C033652:postsynaptic density proteins