[Serum levels of sCD23 and IL-4 concentration in stimulated PBMC in children with atopic diseases].
In this study we estimated the correlation between IgE and sCD23 serum levels, and the concentration of IL-4 in PHA-stimulated PBMC cultures in children with atopic diseases. Children with atopic dermatitis showed a high degree of correlation between sCD23-IgE while in the control group no such relationship was found. We also found no relationship between IL-4 and sCD23 in children with atopic asthma, relationship at children with atopic dermatitis, and no relationship in healthy children. Looking for relationship between IL-4 in PHA-stimulated PBMC and IgE serum levels we discovered a weak negative correlation in children with atopic asthma, a highly positive correlation in children with atopic dermatitis and no relationship in the control group.
Boznański
A
A
Katedra Pediatrii i Klinika Alergologii oraz Kardiologii Dzieciecoj Akademii Medycznej we Wrocławiu.
Machnicki
M
M
Willak-Janz
E
E
D000293:Adolescent; D001249:Asthma / Q000097:blood; D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000097:blood*; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood*; D015847:Interleukin-4 / Q000097:blood*; D017455:Receptors, IgE / Q000097:blood*
D017455:Receptors, IgE; D015847:Interleukin-4; D007073:Immunoglobulin E