title: Use of technetium Tc 99m sestamibi for detection of a parathyroid adenoma in a dog with primary hyperparathyroidism.
abstract: Double-phase parathyroid gland scintigraphy, using technetium Tc 99m sestamibi, correctly identified the existence and location of a parathyroid adenoma in a dog with primary hyperparathyroidism. The parathyroid adenoma was removed surgically 2 days after scintigraphy. An area of focal radionuclide uptake persisted in the region corresponding to the left external parathyroid gland in the delayed-phase image. Delayed-phase images from 3 healthy dogs and a dog with hypercalcemia of malignancy caused by lymphoma did not reveal an area of persistent radiotracer uptake. Double-phase parathyroid gland scintigraphy, using 99mTc-sestamibi, is a simple, rapid, noninvasive test, which can be used for detection and localization of parathyroid adenomas in hypercalcemic dogs. It also can help to differentiate these dogs from dogs with hypercalcemia of malignancy.
authors.affiliation: Department of Veterinary Internal Medicine, Western College of Veterinary Medicine, Saskatoon, Saskatchewan, Canada.
authors.forename: C L
authors.initials: CL
authors.lastname: Matwichuk
authors.forename: S M
authors.initials: SM
authors.lastname: Taylor
authors.forename: A A
authors.initials: AA
authors.lastname: Wilkinson
authors.forename: E M
authors.initials: EM
authors.lastname: Dudzic
authors.forename: G G
authors.initials: GG
authors.lastname: Matte
authors.forename: C A
authors.initials: CA
authors.lastname: Outerbridge
authors.forename: C L
authors.initials: CL
authors.lastname: Schmon
authors.forename: S L
authors.initials: SL
authors.lastname: Ihle
mesh_terms: D000236:Adenoma / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery / Q000662:veterinary*; D000818:Animals; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery; D004285:Dogs; D005260:Female; D006934:Hypercalcemia / Q000000981:diagnostic imaging / Q000209:etiology / Q000662:veterinary; D006961:Hyperparathyroidism / Q000150:complications / Q000209:etiology / Q000662:veterinary*; D008223:Lymphoma / Q000150:complications / Q000662:veterinary; D008297:Male; D010282:Parathyroid Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery / Q000662:veterinary*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi