title: Splenic lymphoma: unusual case with exclusive red pulp involvement.
abstract: A case of Primary Malignant Lymphoma of the Spleen (PMLS) with exclusive red pulp involvement is described and discussed. Although the unusual topographic presentation the authors emphasize the physiologic arrangement of lymphoid cell in splenic red pulp cords that can give origin to the neoplasia. They moreover discuss problems of differential diagnosis with Malignant Histiocytosis (MH), Hairy Cell Leukemia (HCL) and Myeloid Process, both by morphology and immunohistochemistry.
authors.affiliation: Servizio di Anatomia Patologica, Ospedale Desio, Milano.
authors.forename: A
authors.initials: A
authors.lastname: Faravelli
authors.forename: S
authors.initials: S
authors.lastname: Gambini
authors.forename: D
authors.initials: D
authors.lastname: Perego
authors.forename: R
authors.initials: R
authors.lastname: Nobili
authors.forename: M C
authors.initials: MC
authors.lastname: Zoldan
authors.forename: B E
authors.initials: BE
authors.lastname: Leone
authors.forename: L
authors.initials: L
authors.lastname: Giani
mesh_terms: D017809:Fatal Outcome; D006801:Humans; D017093:Liver Failure / Q000209:etiology; D016393:Lymphoma, B-Cell / Q000150:complications / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009181:Mycoses / Q000209:etiology; D009364:Neoplasm Recurrence, Local; D011183:Postoperative Complications; D013154:Spleen / Q000473:pathology; D013160:Splenic Neoplasms / Q000150:complications / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D013203:Staphylococcal Infections / Q000209:etiology; D013369:Subphrenic Abscess / Q000209:etiology