title: [Capillarotrophic insufficiency of the blood microcirculation system as one of the manifestations of general pathology].
abstract: Capillarotrophic failure of the microhemocirculation system may be due to: a) interchangeable microvessel reduction under long-term organ and tissue ischemia, b) their transformation into the depot vessels under conditions of venous congestion, c) underdevelopment of the interchangeable part of the microcirculatory bed in children born prematurely, d) programmed capillary reduction in aged persons. True capillary deficiency in the microhemocirculation system results in centralization of tissue circulation and reduction of its metabolic efficiency. Such type of circulation we qualify as the phenomenon of microhemodynamics centralization. Capillarotrophic failure of the microhemocirculation system should be regarded as one of frequent manifestations of general pathology as its development is associated with many local and systemic human diseases. If applied to some diseases, premature birth and senility, the above phenomenon can be considered as a syndrome of the capillarotrophic deficiency of the microhemocirculation system.
authors.forename: N E
authors.initials: NE
authors.lastname: Iaregin
authors.forename: T N
authors.initials: TN
authors.lastname: Nikolaeva
authors.forename: A V
authors.initials: AV
authors.lastname: Korablev
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000378:metabolism / Q000473:pathology; D002196:Capillaries / Q000378:metabolism / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000378:metabolism / Q000473:pathology; D008875:Middle Aged; D014652:Vascular Diseases / Q000378:metabolism / Q000473:pathology*