Sperm characteristics and hormonal profile before and after treatment with follicle-stimulating hormone in infertile patients.
Fourteen asthenoteratozoospermic (ATZS) patients were treated with 75-IU follicle-stimulating hormone (FSH) injections 3 times a week for 3 months. In the group as a whole, sperm motility, viability, and morphology were improved, but not significantly. Only 3 patients impregnated their wives following treatment. Semen characteristics of the 3 patients whose wives were pregnant showed significant improvement in sperm morphology (p = .001). Only FSH levels were statistically higher (p = .022) than controls. The administration of FSH in weekly doses can improve the fertilization potential of sperm.
Merino
G
G
Gynecologic Endocrinology/Andrology Section, Hospital de Ginecología y Obstetricia, No. 4 Luis Castelazo Ayala, Instituto Mexicano del Seguro Social, México DF, Mexico.
Carranza-Lira
S
S
Martínez-Chéquer
J C
JC
Barahona
E
E
Morán
C
C
Bermúdez
J A
JA
D000328:Adult; D002470:Cell Survival; D005260:Female; D005640:Follicle Stimulating Hormone / Q000494:pharmacology*; D006801:Humans; D007248:Infertility, Male; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D013081:Sperm Motility; D013094:Spermatozoa / Q000187:drug effects* / Q000502:physiology
D005640:Follicle Stimulating Hormone