title: Mobility of hAT transposable elements in the Old World bollworm, Helicoverpa armigera.
abstract: The P, hobo, Hermes, Minos and mariner transposable elements have been successfully used as gene vectors to achieve genetic transformation of Drosophila melanogaster. The hobo transposable element of D. melanogaster, a member of the hAT family of transposable elements, can also transpose in other dipteran species including the house fly Musca domestica and the Queensland fruit fly, Bactrocera tryoni. Another hAT element, Hermes, can also transpose in a wide range of insect species. We report here that both of these hAT elements are also capable of mobility and accurate transposition in the noctuid Helicoverpa armigera and thus may be able to be used as gene vectors that will enable the genetic transformation of this important pest species. Significantly, the ability of hobo to excise in this species is independent of the presence of an exogenous source of hobo transposase, which suggests that H. armigera may possess an endogenous hobo-like transposable element.
authors.affiliation: Division of Entomology, Commonwealth Scientific and Industrial Research Organisation, Canberra, Australia.
authors.forename: A C
authors.initials: AC
authors.lastname: Pinkerton
authors.forename: D A
authors.initials: DA
authors.lastname: O'Brochta
authors.forename: P W
authors.initials: PW
authors.lastname: Atkinson
mesh_terms: D000818:Animals; D004251:DNA Transposable Elements; D005260:Female; D017344:Genes, Insect; D008297:Male; D009036:Moths / Q000235:genetics*
chemical_list: D004251:DNA Transposable Elements