title: [The imaging diagnosis of Sjögren's syndrome: echography, sialography and scintigraphy compared in the study of the salivary glands].
abstract: The aim of the present study was to evaluate the sensitivity and specificity of the ultrasonography, in comparison with other methods of investigation (scintigraphy, sialography, and biopsy), in scanning morphostructural changes in the parotid gland in patient with Sjögren's syndrome. During the period June-October 1994, 34 patients (5 males and 29 females, age ranged between 20 and 88 years) with "sicca syndrome" underwent to echography, scintigraphy, sialography and biopsy. The diagnosis was confirmed or excluded using the European Community Epidemiologic Committee criteria for Sjögren's syndrome. Twenty-two patients out of 34 were affected by Sjögren's syndrome, while the others resulted as control subjects. The ultrasonographic investigation has shown 76.19% of sensitivity and 30.43% of specificity. Even if echography is a non-invasive method, which could be used as preliminary approach for studying the diffused involvement of the parotid gland, at the status of the art, it is not completely reliable for the global evaluation of the morphostructural changes in patients with Sjögren's syndrome, in comparison with the other techniques. Because of the double nature of the gland injury, it appears to be essential the diagnostic integration between echography and sialography.
authors.affiliation: Cattedra di Radiologia, Università degli Studi, Pisa.
authors.forename: V
authors.initials: V
authors.lastname: Napoli
authors.forename: A
authors.initials: A
authors.lastname: Tozzini
authors.forename: E
authors.initials: E
authors.lastname: Neri
authors.forename: A
authors.initials: A
authors.lastname: Calderazzi
authors.forename: M
authors.initials: M
authors.lastname: Gabriele
authors.forename: S
authors.initials: S
authors.lastname: Bonaretti
authors.forename: G
authors.initials: G
authors.lastname: Vinci
authors.forename: C
authors.initials: C
authors.lastname: Vitali
authors.forename: N
authors.initials: N
authors.lastname: Molea
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D012469:Salivary Glands / Q000000981:diagnostic imaging* / Q000473:pathology; D012680:Sensitivity and Specificity; D012796:Sialography; D012859:Sjogren's Syndrome / Q000145:classification / Q000175:diagnosis*; D014463:Ultrasonography