title: Aspergillus endocarditis, myocarditis and pericarditis complicating necrotizing fasciitis. Case report and subject review.
abstract: A patient with Aspergillus endocarditis, myocarditis and pericarditis is described. A 55-year-old man developed necrotizing fasciitis of the lower abdominal wall, pelvis and right thigh. Despite aggressive surgical débridement and antibiotic coverage, the patient died of multisystem organ failure. Autopsy revealed Aspergillus thromboulcerative endocarditis, myocarditis and pericarditis, acute necrotizing fungal bronchopneumonia and mycotic dissemination to brain, kidney and thyroid gland. A review of the literature showed that in the absence of open-heart surgery Aspergillus endocarditis and myocarditis are very uncommon.
authors.affiliation: Institute of Pathology, University of Heidelberg, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Sergi
authors.forename: J
authors.initials: J
authors.lastname: Weitz
authors.forename: W J
authors.initials: WJ
authors.lastname: Hofmann
authors.forename: P
authors.initials: P
authors.lastname: Sinn
authors.forename: A
authors.initials: A
authors.lastname: Eckart
authors.forename: G
authors.initials: G
authors.lastname: Otto
authors.forename: P A
authors.initials: PA
authors.lastname: Schnabel
authors.forename: H F
authors.initials: HF
authors.lastname: Otto
mesh_terms: D001228:Aspergillosis / Q000150:complications* / Q000382:microbiology; D001230:Aspergillus / Q000302:isolation & purification; D001996:Bronchopneumonia / Q000382:microbiology; D004696:Endocarditis / Q000382:microbiology* / Q000473:pathology; D019115:Fasciitis, Necrotizing / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009205:Myocarditis / Q000382:microbiology* / Q000473:pathology; D010493:Pericarditis / Q000382:microbiology* / Q000473:pathology