title: Mouse chromosome 9 involvement in beta-CCM-induced seizures.
abstract: Analysis of beta-CCM induced seizures in three inbred strains of mice, ABP/Le, C57BL/6J and C57BL/6ByJ, and their F1s and F2s progeny, allowed identification of a putative seizure susceptibility controlling locus on chromosome 9 near the short-ear locus. The involvement of a gene in the medial segment of this chromosome in both seizure activity and GABA-controlled behaviour is discussed.
authors.affiliation: Personnalité et Conduites Adaptatives, URA CNRS 1957, Université Paris VI, Hôpital Pitié-Salpêtrière, Paris, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Clément
authors.forename: B
authors.initials: B
authors.lastname: Martin
authors.forename: P
authors.initials: P
authors.lastname: Venault
authors.forename: G
authors.initials: G
authors.lastname: Chapouthier
mesh_terms: D000818:Animals; D002243:Carbolines; D002874:Chromosome Mapping; D003292:Convulsants; D003433:Crosses, Genetic; D004198:Disease Susceptibility; D005260:Female; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008815:Mice, Inbred Strains; D012640:Seizures / Q000139:chemically induced / Q000235:genetics* / Q000503:physiopathology*
chemical_list: D002243:Carbolines; D003292:Convulsants; C036150:beta-carboline-3-carboxylic acid methyl ester