Papillary squamous cell carcinoma of the uterine cervix: report of a case with HPV 16 DNA and brief review.
Papillary squamous cell carcinoma (PSCC) of the uterine cervix is a rare variant of squamous cell carcinoma (SCC). It is characterized by a papillary architecture and markedly atypical epithelium. Invasion and metastasis have been reported. We report a case of PSCC in a 72-year-old woman who subsequently tested positive for HPV 16. To our knowledge, this is the first report of HPV typing in a case of PSCC. Our finding of a high-risk HPV type in PSCC may help explain why PSCC has been reported to have a clinical course similar to that of nonpapillary SCC.
Ollayos
C W
CW
Department of Cellular Pathology, Armed Forces Institute of Pathology, Washington, DC, USA.
Lichy
J
J
Duncan
B W
BW
Ali
I S
IS
D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000821:virology*; D004279:DNA, Viral / Q000302:isolation & purification*; D005260:Female; D006801:Humans; D027383:Papillomaviridae / Q000302:isolation & purification*; D014594:Uterine Neoplasms / Q000473:pathology / Q000821:virology*
D004279:DNA, Viral