Radiation induced oxidative DNA base damage and its repair in liver chromatin DNA of rats upon whole body gamma-irradiation.
The amount of all bases, except for 5,6-dihydroxyuracil were significantly increased in rat DNA upon cobalt-60 gamma-irradiation. Control values were recovered 12 h after irradiation. The extent of DNA damage and repair was different for particular bases.
Zastawny
T H
TH
Department of Clinical Biochemistry, University School of Medical Sciences, Bydgoszcz, Poland.
Czerwińska
B
B
Drzewiecka
B
B
Oliński
R
R
D000818:Animals; D002843:Chromatin / Q000235:genetics*; D004247:DNA / Q000528:radiation effects; D004249:DNA Damage; D004260:DNA Repair; D008099:Liver / Q000528:radiation effects*; D008297:Male; D018384:Oxidative Stress; D051381:Rats; D017208:Rats, Wistar
D002843:Chromatin; D004247:DNA