Arthritis associated with circulating immune complexes following administration of intravenous immunoglobulin therapy in a patient with chronic inflammatory demyelinating polyneuropathy.
Intravenous immunoglobulin is viewed as a relatively safe treatment for several neurologic disorders. I report arthritis associated with elevated circulating immune complexes and abnormalities of serum complement components which is a rare complication with modern preparations of immunoglobulin-gamma.
Lisak
R P
RP
Department of Neurology, Wayne State University, Detroit, MI 48201, USA.
D000936:Antigen-Antibody Complex / Q000097:blood*; D001168:Arthritis / Q000150:complications / Q000276:immunology*; D002908:Chronic Disease; D003711:Demyelinating Diseases / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000009:adverse effects*; D008875:Middle Aged; D010523:Peripheral Nervous System Diseases / Q000150:complications / Q000188:drug therapy / Q000276:immunology; D012713:Serum Sickness / Q000150:complications / Q000276:immunology
D000936:Antigen-Antibody Complex; D016756:Immunoglobulins, Intravenous