title: Metastasis of chondrosarcoma.
abstract: This study was undertaken to analyse metastases of patients with intermediate- or high-grade chondrosarcomas. Out of 24 intermediate-grade tumours, 5 (21%) developed metastases, as did 6 of 10 high-grade tumors (60%) (P = 0.04). Four patients developed pulmonary metastasis only, 5 developed both pulmonary metastasis and metastases of the other sites. Two patients showed a rare metastatic pattern: bone metastases only. The metastasis rate in the primary chondrosarcoma (42%) was higher than that in the secondary chondrosarcomas (0%) (P = 0.03). The metastasis rate was higher in patients with local recurrence (86%) than in those without local recurrence (19%) (P = 0.01). In 5 of 6 patients who had a local relapse and metastasis, the interval between the two relapses was a few months.
authors.affiliation: Department of Orthopaedics, Westfalische Wilhelms-University, Münster, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Ozaki
authors.forename: A
authors.initials: A
authors.lastname: Hillmann
authors.forename: N
authors.initials: N
authors.lastname: Linder
authors.forename: S
authors.initials: S
authors.lastname: Blasius
authors.forename: W
authors.initials: W
authors.lastname: Winkelmann
mesh_terms: D003587:Cytomegalovirus / Q000235:genetics*; D003586:Cytomegalovirus Infections / Q000150:complications / Q000821:virology; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D016679:Genome, Viral; D006801:Humans; D008207:Lymphatic Metastasis; D027383:Papillomaviridae / Q000235:genetics*; D030361:Papillomavirus Infections / Q000150:complications / Q000821:virology; D016133:Polymerase Chain Reaction; D014412:Tumor Virus Infections / Q000150:complications / Q000821:virology; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000821:virology*
chemical_list: D004279:DNA, Viral