title: Mutagenicity studies on erythritol in bacterial reversion assay systems and in Chinese hamster fibroblast cells.
abstract: The sweetener erythritol tested negative in reverse mutation assays using Salmonella typhimurium strains TA98, TA100, TA1535, and TA1537 and the WP2 uvrA strain of Escherichia coli. Erythritol tested negative in chromosome aberration tests using the Chinese hamster fibroblast cell line CHL/IU.
authors.affiliation: Nikken Chemicals Co., Ltd., Saitama, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kawamura
authors.forename: Y
authors.initials: Y
authors.lastname: Saito
authors.forename: M
authors.initials: M
authors.lastname: Imamura
authors.forename: J P
authors.initials: JP
authors.lastname: Modderman
mesh_terms: D000818:Animals; D002460:Cell Line; D002869:Chromosome Aberrations; D002875:Chromosomes / Q000187:drug effects; D006224:Cricetinae; D003412:Cricetulus; D004896:Erythritol / Q000633:toxicity*; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics; D005347:Fibroblasts / Q000187:drug effects* / Q000648:ultrastructure; D009152:Mutagenicity Tests; D009153:Mutagens / Q000633:toxicity*; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics; D013549:Sweetening Agents / Q000633:toxicity*
chemical_list: D009153:Mutagens; D013549:Sweetening Agents; D004896:Erythritol