title: Improved management of selective cerebral perfusion in aortic arch surgery.
abstract: To establish a safe and reliable method for cerebral protection in aortic arch surgery, the authors attempted antegrade selective cerebral perfusion (SCP) based on the characteristics of jugular venous oxygen saturation (SjO2). Twenty patients were divided into two groups: a control group and SCP group. In the control group, in 13 adult patients undergoing cardiac surgery using standard hypothermic cardiopulmonary bypass, the relationship between SjO2 and nasopharyngeal temperature (NPT) during rewarming showed an inverse linear correlation:SjO2 = -2.3 NPT + 133 (r = 0.616). In the SCP group, seven patients with aortic arch aneurysm underwent surgery using SCP performed through direct cannulation of the innominate and left carotid arteries. While on SCP (83 +/- 24 min), the blood was warmed from 28 to 36 degrees C. Cerebral perfusion pressure of 40-60 mm Hg was necessary to maintain the SjO2 equal to the value in the control group at each NPT during SCP in all seven patients. None of the patients had any post operative complications. Our experience suggests that SCP can be safely performed at both mild hypothermia and normothermia under monitoring of perfusion pressure and SjO2 in aortic arch surgery.
authors.affiliation: Division of Cardiovascular Surgery, Osaka Police Hospital, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Matsuwaka
authors.forename: T
authors.initials: T
authors.lastname: Sakakibara
authors.forename: M
authors.initials: M
authors.lastname: Mitsuno
authors.forename: A
authors.initials: A
authors.lastname: Yagura
authors.forename: H
authors.initials: H
authors.lastname: Shintani
authors.forename: M
authors.initials: M
authors.lastname: Yoshikawa
authors.forename: T
authors.initials: T
authors.lastname: Hori
authors.forename: N
authors.initials: N
authors.lastname: Shinohara
mesh_terms: D000328:Adult; D000368:Aged; D017545:Aortic Aneurysm, Thoracic / Q000503:physiopathology* / Q000601:surgery*; D001243:Assisted Circulation / Q000379:methods*; D002560:Cerebrovascular Circulation; D005260:Female; D006324:Heart Arrest, Induced; D006801:Humans; D007036:Hypothermia, Induced; D008297:Male; D008875:Middle Aged; D010477:Perfusion