title: [Nocardia respiratory infection in patients with chronic obstructive lung disease].
abstract: Pulmonary nocardiosis is a respiratory infection which is usually described in the immunocompromised. We report three cases in patients suffering from chronic airflow obstruction. In two cases there was a parenchymal disorder and in one case bronchial suppuration without involvement of the alveolar region. The diagnosis was made in all cases by bacteriological examination from specimens obtained at fiberoptic bronchoscopy. The outcome was favourable in all three cases after appropriate treatment. These observations underline the diversity of the clinical forms of respiratory nocardiosis. Furthermore, it demonstrates their possible occurrence in non-immunocompromised patients and the need to look for this germ specifically in long drawn infections. A bacteriological diagnosis is vital to start early and appropriate antibiotic therapy which should be prolonged because of the risk of recurrence and disseminated infection.
authors.affiliation: Service de Pneumologie-Allergologie, CHU Toulouse-Rangueil, Toulouse.
authors.forename: L
authors.initials: L
authors.lastname: Lacassagne
authors.forename: A
authors.initials: A
authors.lastname: Didier
authors.forename: M
authors.initials: M
authors.lastname: Murrisespin
authors.forename: R M
authors.initials: RM
authors.lastname: Rouquet
authors.forename: D
authors.initials: D
authors.lastname: Clave
authors.forename: J
authors.initials: J
authors.lastname: Lemozy
authors.forename: J
authors.initials: J
authors.lastname: Giron
authors.forename: P
authors.initials: P
authors.lastname: Leophonte
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009617:Nocardia Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents