title: Set-up, improvement, and evaluation of an electrohydraulic total artificial heart with a separately placed energy converter.
abstract: The authors have been developing an electrohydraulic total artificial heart (TAH) system with a separately placed electrohydraulic energy converter to minimize anatomic constraints in the pericardial space. Improvements to the system and current status of the development are reported. The energy converter was miniaturized to improve implantability, and its thickness was reduced to 54 mm. System efficiency was increased by suppressing rush current at the time of motor reversal. Maximum cardiac output of the TAH system was 9 L/min, and maximum system efficiency increased to 10%. The blood pump system was implanted easily in the body of a 57 kg calf, and no significant temperature rise on the energy converter surface was observed. As the next step, main components were integrated into a total system. The transcutaneous energy transfer system could supply power to the TAH without a decline in pump performance, and the internal battery could support the system at 6.5 L/min of cardiac output for 1 hour without a decrease in cardiac output. The authors consider the TAH system with a separately placed energy converter the most promising approach to development of a TAH for smaller sized patients.
authors.affiliation: Department of Artificial Organs, National Cardiovascular Center Research Institute, Osaka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Masuzawa
authors.forename: Y
authors.initials: Y
authors.lastname: Taenaka
authors.forename: E
authors.initials: E
authors.lastname: Tatsumi
authors.forename: J M
authors.initials: JM
authors.lastname: Ahn
authors.forename: T
authors.initials: T
authors.lastname: Ohno
authors.forename: K
authors.initials: K
authors.lastname: Toda
authors.forename: K
authors.initials: K
authors.lastname: Miyazaki
authors.forename: Y
authors.initials: Y
authors.lastname: Wakisaka
authors.forename: K
authors.initials: K
authors.lastname: Eya
authors.forename: Y
authors.initials: Y
authors.lastname: Baba
authors.forename: T
authors.initials: T
authors.lastname: Nakatani
authors.forename: H
authors.initials: H
authors.lastname: Takano
authors.forename: C
authors.initials: C
authors.lastname: Uyama
authors.forename: K
authors.initials: K
authors.lastname: Koshiji
authors.forename: Y
authors.initials: Y
authors.lastname: Fukui
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: K
authors.initials: K
authors.lastname: Tsuchimoto
authors.forename: K
authors.initials: K
authors.lastname: Tsukahara
mesh_terms: D000818:Animals; D001835:Body Weight; D002302:Cardiac Output; D002417:Cattle; D004582:Electronics, Medical / Q000295:instrumentation; D005069:Evaluation Studies as Topic; D006354:Heart, Artificial; D006801:Humans; D019563:Mechanics; D011474:Prosthesis Design