title: Reproductive outcome following hysteroscopic adhesiolysis in Asherman's syndrome.
abstract: OBJECTIVE
  To determine whether hysteroscopic adhesiolysis improves reproductive outcome in women with Asherman's syndrome and pregnancy failure.
  
  
  METHODS
  Ninety consecutive women who had undergone hysteroscopic adhesiolysis of intrauterine adhesions during a 5-year period. Only women in whom at least two previous pregnancies had ended with either a spontaneous abortion or a premature delivery accompanied by fetal or neonatal mortality and a hysteroscopic diagnosis of intrauterine adhesions were enrolled.
  
  
  RESULTS
  Whereas pregnancy outcome prior to the operation was 18.3% term deliveries, 3.3% premature deliveries, 62.4% first-trimester abortions, and 16.0% late abortions, after hysteroscopic adhesiolysis pregnancy outcome was 68.6% term deliveries, 9.3% premature deliveries, 17.4% first-trimester abortions, and 4.7% late abortions. In women with two previous unsuccessful pregnancies, the operative success rate measured by delivering a healthy newborn improved from 18.3% preoperatively to 64% postoperatively. In women with three or more unsuccessful pregnancies the success rate improved from 18.3% to 75%. Successful outcome of adhesiolysis was observed in 61.9% of mild (stage I) and in 70.6% of moderate to severe cases (stages II and III) of intrauterine adhesions.
  
  
  CONCLUSIONS
  Hysteroscopic adhesiolysis in women with Asherman's syndrome and poor reproductive performance contributes significantly to a successful reproductive outcome.
authors.affiliation: Department of Obstetrics and Gynecology Kaplan Hospital Rehovot, Israel.
authors.forename: Z
authors.initials: Z
authors.lastname: Katz
authors.forename: A
authors.initials: A
authors.lastname: Ben-Arie
authors.forename: S
authors.initials: S
authors.lastname: Lurie
authors.forename: M
authors.initials: M
authors.lastname: Manor
authors.forename: V
authors.initials: V
authors.lastname: Insler
mesh_terms: D005260:Female; D006801:Humans; D015907:Hysteroscopy; D011184:Postoperative Period; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D011446:Prospective Studies; D013577:Syndrome; D000267:Tissue Adhesions / Q000601:surgery / Q000628:therapy; D014591:Uterine Diseases / Q000601:surgery / Q000628:therapy*; D014599:Uterus / Q000601:surgery*