title: Hypomelanosis of Ito and brain abnormalities: MRI findings and literature review.
abstract: We report the results of a 14-year retrospective study of brain MRI abnormalities in 12 pediatric patients presenting with hypomelanosis of Ito (HI). Miscellaneous brain abnormalities were found: one patient had a medulloblastoma, three had cortical malformations, and five demonstrated "minor" abnormalities such as dilated Virchow-Robin spaces or brain atrophy. We emphasize the polymorphism of brain abnormalities associated with HI.
authors.affiliation: Service de Radiologie, Hôpital St. Vincent de Paul, 82 avenue Denfert Rochereau, F-75674 Paris Cedex 14, France.
authors.forename: J
authors.initials: J
authors.lastname: Steiner
authors.forename: C
authors.initials: C
authors.lastname: Adamsbaum
authors.forename: I
authors.initials: I
authors.lastname: Desguerres
authors.forename: G
authors.initials: G
authors.lastname: Lalande
authors.forename: F
authors.initials: F
authors.lastname: Raynaud
authors.forename: G
authors.initials: G
authors.lastname: Ponsot
authors.forename: G
authors.initials: G
authors.lastname: Kalifa
mesh_terms: D000293:Adolescent; D001284:Atrophy; D001921:Brain / Q000002:abnormalities* / Q000473:pathology; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis; D002552:Cerebral Ventricles / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D004108:Dilatation, Pathologic / Q000150:complications / Q000175:diagnosis; D005260:Female; D006801:Humans; D006984:Hypertrophy; D017496:Hypopigmentation / Q000150:complications; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008527:Medulloblastoma / Q000150:complications / Q000175:diagnosis; D010859:Pigmentation Disorders / Q000150:complications*; D011110:Polymorphism, Genetic; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed