[Motility of the gastric antrum and the gallbladder following oral administration of sulfate-bicarbonate].
The authors evaluate the influence of a sulphate-bicarbonate mineral water on gastric emptying and cholecystic motility. Nine healthy volunteers drunk at settled intervals and with same procedures equal doses of mineral water and tap water on alternate days. Ultrasonographic evaluation of the gastric emptying and cholecystic volumes was performed before and after mineral water and top water drinks at settled intervals. The mean values of the gastric and the cholecystic volumes were calculated and compared at the single times. The results showed a significant colecystocinetic effect of the mineral water compared with tap water. No difference was observed in the gastric emptying with the mineral and tap water. Our work contributes to the knowledge of the pharmacodynamic effects of the mineral water employed and confirms its usefulness in the syndromes based on alterations in bile secretion and bile excretion in duodenum.
Grossi
F
F
Istituto di Idrologia Medica, Università degli Studi di Roma, La Sapienza.
Fontana
M
M
Conti
R
R
Mastroianni
S
S
Lazzari
S
S
Messini
F
F
Piccarreta
U
U
Grassi
M
M
D000284:Administration, Oral; D001639:Bicarbonates / Q000008:administration & dosage / Q000494:pharmacology*; D005704:Gallbladder / Q000187:drug effects*; D005746:Gastric Emptying / Q000187:drug effects; D005769:Gastrointestinal Motility / Q000187:drug effects*; D006801:Humans; D008900:Mineral Waters; D011706:Pyloric Antrum / Q000187:drug effects*; D013431:Sulfates / Q000008:administration & dosage / Q000494:pharmacology*
D001639:Bicarbonates; D008900:Mineral Waters; D013431:Sulfates