Chloride channels in renal epithelial cells.
Chloride channels are found throughout the nephron. Many chloride channels expressed in the kidney have now been cloned. The CIC family of voltage-dependent chloride channels accounts for most of the known renal chloride channels. Unfortunately, relatively little is known concerning their functional properties. The role that chloride channels may play in renal disease has only recently been addressed.
Reeves
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WB
Department of Internal Medicine, University of Arkansas College of Medicine, Little Rock 72205, USA.
Andreoli
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TE
D018118:Chloride Channels / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D004847:Epithelial Cells; D004848:Epithelium / Q000378:metabolism; D006801:Humans; D007668:Kidney / Q000378:metabolism*; D007674:Kidney Diseases / Q000235:genetics / Q000378:metabolism*; D009124:Muscle Proteins / Q000235:genetics / Q000378:metabolism; D016891:Polycystic Kidney, Autosomal Dominant / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism
C086321:CLC-1 channel; D018118:Chloride Channels; D009124:Muscle Proteins; D012333:RNA, Messenger