Short stature due to growth hormone deficiency associated with Cushing's disease and ulcerative colitis.
We report a rare case of Cushing's disease associated with ulcerative colitis in a patient primarily treated with growth hormone due to short stature. At the age of fifteen years, the patient had a short stature due to GHD and was treated with the extracted GH for a short period. At the age of twenty-one years, his body weight gradually increased and, based on the results of several tests, he was diagnosed with Cushing's disease and GHD was observed in our patient. The excess secretion attenuation of pituitary hormones with reduced secretion periods as well as the relation between ulcerative colitis and elevated plasma cortisol concentrations is briefly discussed in this paper.
Kotake
M
M
Department of Internal Medicine, Fujita-Health University School of Medicine, Aichi, Japan.
Nakai
A
A
Mokuno
T
T
Oda
N
N
Sawai
Y
Y
Itoh
Y
Y
Shimazaki
K
K
Kato
R
R
Hayakawa
N
N
Uchikawa
A
A
Oiso
Y
Y
Hirooka
Y
Y
Mitsuma
T
T
Itoh
M
M
Nagasaka
A
A
D000328:Adult; D001772:Blood Cell Count; D001846:Bone Development / Q000187:drug effects; D003093:Colitis, Ulcerative / Q000150:complications*; D003480:Cushing Syndrome / Q000150:complications*; D006130:Growth Disorders / Q000209:etiology*; D006680:HLA Antigens / Q000032:analysis; D006728:Hormones / Q000097:blood; D019382:Human Growth Hormone / Q000172:deficiency* / Q000627:therapeutic use*; D006801:Humans; D008297:Male
D006680:HLA Antigens; D006728:Hormones; D019382:Human Growth Hormone