Betulinans A and B, two benzoquinone compounds from Lenzites betulina.
Two lipid peroxidation inhibitors, designated as betulinans A (1) and B (2), were isolated from the MeOH extract of Lenzites betulina. The structures of these compounds have been determined to be 2,5-diphenyl-3,6-dimethoxy-p-benzoquinone and 2-phenyl-3-methoxy-[1H-2-benzopyran][4,3-e][p]benzoquinone, respectively, on the basis of various spectral data. Betulinans A and B inhibited lipid peroxidation with IC50 values of 0.46 and 2.88 micrograms/mL, respectively.
Lee
I K
IK
Korea Research Institute of Bioscience and Biotechnology, Yusong, Taejon, Korea.
Yun
B S
BS
Cho
S M
SM
Kim
W G
WG
Kim
J P
JP
Ryoo
I J
IJ
Koshino
H
H
Yoo
I D
ID
D000818:Animals; D000975:Antioxidants / Q000302:isolation & purification* / Q000494:pharmacology; D016227:Benzoquinones / Q000302:isolation & purification* / Q000494:pharmacology; D066298:In Vitro Techniques; D015227:Lipid Peroxidation / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism; D011124:Polyporaceae / Q000737:chemistry*; D051381:Rats; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D014810:Vitamin E / Q000494:pharmacology; D000094062:Betulinic Acid
D000975:Antioxidants; D016227:Benzoquinones; D014810:Vitamin E; C103457:betulinan A; D000094062:Betulinic Acid; C103458:betulinan B