Coeliac-type permanent-tooth enamel defects.
Systematic and chronologically distributed permanent-tooth so-called coeliac-type enamel defects are highly prevalent both in children and adults with coeliac disease (gluten-sensitive enteropathy) and dermatitis herpetiformis. Coeliac-type enamel defects were also found in healthy first-degree family members of coeliac disease patients. Our family study showed that these persons with the typical defected enamel were genetically similar to coeliac disease patients (A1;B8;DR3). As coeliac disease patients are often clinically silent with no gastrointestinal symptoms, or they complain only of minimal abdominal discomfort, both dentists and physicians could select patients with coeliac-type enamel defects for gastroenterological and dermatological consultations, including serological screening tests and later jejunal mucosal biopsy.
Aine
L
L
Department of Oral and Maxillofacial Surgery, Tampere University Hospital, Finland.
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002446:Celiac Disease / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D003743:Dental Enamel / Q000002:abnormalities*; D003744:Dental Enamel Hypoplasia / Q000453:epidemiology* / Q000235:genetics / Q000473:pathology; D003874:Dermatitis Herpetiformis / Q000150:complications / Q000235:genetics; D006801:Humans; D007223:Infant; D015995:Prevalence