title: Collagenous macrophage scavenger receptors.
abstract: Collagen, the most abundant protein in the human body, is a major constituent of extracellular matrix. Among macrophage membrane proteins, type I and II scavenger receptors and MARCO contain a collagenous domain. Analysis of type I and II receptor knockout mice and histochemical studies indicate that these proteins play roles in scavenger, adhesion and host defense functions of macrophages.
authors.affiliation: Department of Molecular Biology and Medicine, University of Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Kodama
authors.forename: T
authors.initials: T
authors.lastname: Doi
authors.forename: H
authors.initials: H
authors.lastname: Suzuki
authors.forename: K
authors.initials: K
authors.lastname: Takahashi
authors.forename: Y
authors.initials: Y
authors.lastname: Wada
authors.forename: S
authors.initials: S
authors.lastname: Gordon
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000502:physiology; D001161:Arteriosclerosis / Q000235:genetics / Q000378:metabolism; D002352:Carrier Proteins / Q000378:metabolism*; D015815:Cell Adhesion Molecules / Q000378:metabolism; D003094:Collagen / Q000737:chemistry / Q000378:metabolism; D006801:Humans; D008264:Macrophages / Q000378:metabolism*; D008565:Membrane Proteins / Q000378:metabolism*; D051379:Mice; D018345:Mice, Knockout; D011971:Receptors, Immunologic / Q000378:metabolism*; D018110:Receptors, Lipoprotein; D051116:Receptors, Scavenger; D051122:Scavenger Receptors, Class B
chemical_list: D002352:Carrier Proteins; D015815:Cell Adhesion Molecules; C490460:MARCO protein, human; C092228:Marco protein, mouse; D008565:Membrane Proteins; D011971:Receptors, Immunologic; D018110:Receptors, Lipoprotein; D051116:Receptors, Scavenger; C454739:Scarb1 protein, mouse; D051122:Scavenger Receptors, Class B; D003094:Collagen