Four novel cycloartane glycosides from Astragalus oleifolius.
Four novel cycloartane-type triterpene glycosides, macrophyllosaponins A-D (1-4) were isolated from the roots of Astragalus oleifolius. By means of chemical (acetylation, alkaline hydrolysis) and spectroscopic methods (IR, 1D- and 2D-NMR, FABMS), their structures were established as 3-O-alpha-L-rhamnopyranosyl-24-O-(4"-O-acetyl)-beta-D-xylopyranosyl-1 alpha,3 beta,7 beta,24(S), 25-pentahydroxycycloartane (1), 3-O-alpha-L-rhamnopyranosyl-24-O-beta-D-xylopyranosyl-1 alpha,3 beta, 7 beta,24(S), 25-pentahydroxycycloartane (2), 3-O-alpha-L-rhamnopyranosyl-25-O-beta-D-glucoyranosyl-1 alpha, 3 beta,7 beta,24(S),25-pentahydroxycycloartane (3), and 3-O-alpha-L-rhamnopyranosyl-24-O-(2-O-beta-D-xylopyranosyl) -beta-D-xylopyranosyl-1 alpha,3 beta,7 beta,24(S), 25-pentahydroxycycloartane (4).
Caliş
I
I
Department of Pharmacognosy, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey.
Zor
M
M
Saracoğlu
I
I
Işimer
A
A
Rüegger
H
H
D002240:Carbohydrate Sequence; D002853:Chromatography, Liquid; D007887:Fabaceae / Q000737:chemistry*; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013055:Spectrophotometry, Infrared; D014421:Turkey
D012503:Saponins