title: Low adrenal androgen output in patients with abnormal laryngeal epithelium.
abstract: We present 16 new patients who had abnormal vocal cord biopsies. Each had a serum sex hormone profile performed on the morning of the procedure. The striking abnormality was that 12 (75%) had low dehydroepiandrosterone sulphate (DHEAS), the main adrenal androgen, and four of these had prepubertal levels.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Southampton General Hospital, UK.
authors.forename: W
authors.initials: W
authors.lastname: Colquhoun-Flannery
authors.forename: J A
authors.initials: JA
authors.lastname: Carruth
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood; D001706:Biopsy; D002278:Carcinoma in Situ / Q000097:blood* / Q000473:pathology; D019314:Dehydroepiandrosterone Sulfate / Q000097:blood*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000097:blood* / Q000473:pathology; D007827:Laryngitis / Q000097:blood* / Q000473:pathology; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D010865:Pilot Projects; D013739:Testosterone / Q000097:blood; D014827:Vocal Cords / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor; D013739:Testosterone; D019314:Dehydroepiandrosterone Sulfate; D007986:Luteinizing Hormone