An unusual case of cytomegalovirus infection.
We describe the case of a nonimmunocompromised middle age man, who presented with a history of fever, nausea, disturbance of consciousness, peripheral eosinophilia and a bone marrow eosinophilic hyperplasia. A persistent unexplained eosinophilia was initially interpreted as a sign of the hypereosinophilic syndrome because all known causes of secondary eosinophilia had been excluded and there were evidence of multiorgan dysfunction. A cervical lymph node biopsy was remarkable for malignant T cell lymphoma according to the hypothesis that patients with the hypereosinophilic syndrome should be carefully examined for an underlying proliferation of clonal T cells. The patient died of CID after 3 months of hospitalization. At autopsy he was found to have a generalized CMV infection.
Ballotta
M R
MR
Servizio di Anatomia ed Istologia Patologica, Ospedale Civile, Rovigo.
Borghi
L
L
Borin
P
P
D003586:Cytomegalovirus Infections / Q000150:complications / Q000175:diagnosis*; D017809:Fatal Outcome; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000175:diagnosis* / Q000209:etiology; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009894:Opportunistic Infections / Q000150:complications / Q000175:diagnosis*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000276:immunology