title: Microrough surface of metallic biomaterials: a literature review.
abstract: In this paper, four aspects of microrough surface of metallic biomaterials are reviewed: i.e., the preparation of microrough surface, the technology of surface roughness measurement, the parameters of roughness and the bio-effect of microrough surface. Microrough surfaces (roughness below 50 microns) are easily prepared and conveniently detected in practice. Microrough surfaces allow early better adhesion of mineral ions or atoms, biomolecules, and cells, form firmer fixation of bone or connective tissue, result in thinner tissue-reaction-layer with inflammatory cells decreased or absent, and prevent microorganism adhesion and plaque accumulation, when compared with the smooth surfaces.
authors.affiliation: Department of Materials Science and Engineering, Zhejiang University, Hangzhou, P.R. China. wen@ee.nus.sg
authors.forename: X
authors.initials: X
authors.lastname: Wen
authors.forename: X
authors.initials: X
authors.lastname: Wang
authors.forename: N
authors.initials: N
authors.lastname: Zhang
mesh_terms: D001672:Biocompatible Materials; D016723:Bone Remodeling; D002448:Cell Adhesion; D002465:Cell Movement; D015921:Dental Implants; D005347:Fibroblasts / Q000502:physiology; D008670:Metals; D016348:Osseointegration; D019736:Prostheses and Implants; D013499:Surface Properties
chemical_list: D001672:Biocompatible Materials; D015921:Dental Implants; D008670:Metals