Juvenile generalized pustular psoriasis.
A 4-year-old boy had a generalized, confluent, pustular eruption on an erythematous base of three weeks' duration. He was febrile and toxic. He had had a similar problem at age 5 months that lasted for about four weeks. The child was initially treated conservatively, but later developed erythroderma and became increasingly toxic. This necessitated administration of oral methotrexate 2.5 mg/day at weekly intervals. After two pulses there was marked improvement in his psoriasis.
Kalla
G
G
Department of Dermatology, S.T.D., and Leprosy, Dr. Sampurnanand Medical College, Jodhpur, India.
Goyal
A M
AM
D017668:Age of Onset; D001707:Biopsy, Needle; D002675:Child, Preschool; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage / Q000627:therapeutic use*; D011565:Psoriasis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology; D012867:Skin / Q000473:pathology
D003879:Dermatologic Agents; D008727:Methotrexate