Studies of dentate granule cell modulation: paired-pulse responses in freely moving rats at three ages.
Dentate granule cell population responses to paired-pulse stimulations applied to the perforant pathway across a range of interpulse intervals (IPI) were examined in freely moving rats at 15, 30, and 90 days of age. The profile of the paired-pulse index (PPI), a measure of the type and degree of modulation of dentate granule cell excitability, was shown to change significantly as a function of age.
Bronzino
J D
JD
Trinity College, Department of Engineering and Computer Science, Hartford, CT 06106, USA.
Blaise
J H
JH
Austin-LaFrance
R J
RJ
Morgane
P J
PJ
D000818:Animals; D018891:Dentate Gyrus / Q000166:cytology / Q000254:growth & development / Q000502:physiology*; D004558:Electric Stimulation; D005071:Evoked Potentials / Q000502:physiology; D005246:Feedback; D008297:Male; D009068:Movement / Q000502:physiology*; D009474:Neurons / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley