Kurasoins A and B, new protein farnesyltransferase inhibitors produced by Paecilomyces sp. FO-3684. I. Producing strain, fermentation, isolation, and biological activities.
Uchida
R
R
Research Center for Biological Function, Kitasato Institute, Tokyo, Japan.
Shiomi
K
K
Inokoshi
J
J
Masuma
R
R
Kawakubo
T
T
Tanaka
H
H
Iwai
Y
Y
Omura
S
S
D019883:Alkyl and Aryl Transferases; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D051231:Farnesyltranstransferase; D005285:Fermentation; D007211:Indoles / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D010143:Paecilomyces / Q000145:classification / Q000378:metabolism*; D010636:Phenols / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014166:Transferases / Q000037:antagonists & inhibitors*
D004791:Enzyme Inhibitors; D007211:Indoles; D010636:Phenols; C102430:kurasoin A; C102431:kurasoin B; D014166:Transferases; D019883:Alkyl and Aryl Transferases; D051231:Farnesyltranstransferase