Foreign body reactions to monofilament and braided polypropylene mesh used as preperitoneal implants in pigs.
OBJECTIVE
To compare the foreign body reaction of the monofilament polypropylene (Prolene) mesh, and the multifilament Surgipro mesh. Both types of mesh are widely used in laparoscopic inguinal hernia repair.


METHODS
Prospective experimental study.


METHODS
University hospital, The Netherlands.


METHODS
Six female Yorkshire & Dutch landway pigs.


METHODS
Laparoscopic transabdominal implantation of six Surgipro meshes and six Prolene meshes in 12 inguinal sites.


METHODS
At 3, 6, and 12 weeks after implantation the foreign body reaction was measured by counting multinucleated giant cells at the mesh-tissue interface.


RESULTS
At all times the numbers of multinucleated giant cells at the mesh tissue interface were significantly larger with Surgipro than with Prolene (p < 0.001).


CONCLUSIONS
There is significantly more foreign body reaction after implantation of Surgipro than Prolene mesh.
Beets
G L
GL
Department of Surgery, University Hospital Maastricht, The Netherlands.
Go
P M
PM
van Mameren
H
H
D000818:Animals; D005260:Female; D005549:Foreign-Body Reaction / Q000473:pathology*; D010535:Laparoscopy; D011126:Polypropylenes; D019736:Prostheses and Implants; D013526:Surgical Mesh; D013537:Sutures; D013552:Swine
D011126:Polypropylenes