Cardiac spectral power reflects parasympathetic but not sympathetic nervous system activity in a clinical population.
The purpose of this short communication is to report our clinical findings regarding the use of the low frequency (LF, 0.02-0.15 Hz) and high frequency (HF, > 0.15 Hz) components of the spectral decomposition of heart-rate as indices of sympathetic (SNS) and parasympathetic nervous system (PNS) activity, respectively. Thirty-two females with histologically confirmed ovarian cancer, ranging in age from 46-72 years, participated in an autonomic assessment protocol consisting of a resting heart rate recording and several ANS function tests. The LF, HF and total power measures from the spectral decomposition were highly correlated with one another. In addition, the spectral components were most highly correlated with measures of PNS activity, i.e. standard deviation of heart rate at rest and the ratio of the six longest to the six shortest R-R intervals during deep breathing (E:I ratio). It is concluded, as other researchers have stated, that the use of the HF component of the HR spectrum as a measure of PNS activity is warranted, but caution must be used when interpreting the LF component.
Muth
E R
ER
Department of Psychology, Pennsylvania State University, University Park 16802, USA. emuth@med.hmc.psu.edu
Morrow
G R
GR
Jiang
W
W
Stern
R M
RM
Dubeshter
B
B
D000368:Aged; D001794:Blood Pressure / Q000502:physiology; D002319:Cardiovascular System / Q000294:innervation*; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D010275:Parasympathetic Nervous System / Q000502:physiology*; D013564:Sympathetic Nervous System / Q000502:physiology*; D014636:Valsalva Maneuver / Q000502:physiology