[Molecular mechanism of cell cycle control].
The eukaryotic cell cycle is believed to be regulated by cyclin/CDK (cyclin-dependent kinase). The activity of cyclin/CDK has recently been found to be regulated by a family of small CDK inhibitor proteins. Moreover, the tumor suppressor gene products have been revealed to function as the regulator of cell cycle progression.
Akiyama
T
T
Dept. of Oncogene Res. Res. Inst. for Microbial Disease, Osaka Univ.
D002453:Cell Cycle / Q000235:genetics*; D018844:Cyclin-Dependent Kinases / Q000378:metabolism / Q000502:physiology; D016213:Cyclins / Q000378:metabolism / Q000502:physiology; D016147:Genes, Tumor Suppressor; D006801:Humans; D009369:Neoplasms / Q000209:etiology*; D010766:Phosphorylation
D016213:Cyclins; D018844:Cyclin-Dependent Kinases