title: Multicentric reticulohistiocytosis.
abstract: We describe a 42-year-old man with a five-year history of arthritis mutilans-like destructive joint changes and with a one-year history of nodules on the fingers, ears, oral mucosa, pharynx, larynx, vocal cords, some being ulcerated and haemorrhagic. He was diagnosed as having rheumatoid arthritis; however, biopsies from the nodules on the oral mucosa and ear revealed multicentric reticulohistiocytosis. The large nodule over the olecranon process, simulating a rheumatoid nodule but diagnosed as multicentric reticulohistiocytosis with biopsy; ulcerated and haemorrhagic nodules on the oral mucosa; and rapidly progressive joint destructions make our case interesting.
authors.affiliation: Department of Medicine, Division of Rheumatology, Ege University, School of Medicine, Izmir, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Kocanaogullari
authors.forename: H
authors.initials: H
authors.lastname: Ozsan
authors.forename: F
authors.initials: F
authors.lastname: Oksel
authors.forename: G
authors.initials: G
authors.lastname: Ozturk
authors.forename: G
authors.initials: G
authors.lastname: Kandiloglu
authors.forename: E E
authors.initials: EE
authors.lastname: Ustun
authors.forename: E
authors.initials: E
authors.lastname: Doganavsargil
mesh_terms: D000328:Adult; D018501:Antirheumatic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000503:physiopathology; D001379:Azathioprine / Q000008:administration & dosage / Q000627:therapeutic use; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D015614:Histiocytosis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male
chemical_list: D018501:Antirheumatic Agents; D001379:Azathioprine