title: Criminal responsibility and solvent exposure.
abstract: This case report contains the history of a man's exposure to benzene, trichloroethylene, and toluene. J suffered acutely from classic symptoms of toxic exposure to these compounds, such as fatigue, clumsiness, staggering, and hematopoietic depression. During his medical hospitalization, he was exposed to further organic insults, such as being treated with medications like Cytoxan and medications to treat an abscess in his right parietal lobe. After the acute exposure and after the abscess had resolved, his functioning on neuropsychological testing was still depressed, as he had a Full Scale IQ of 105, whereas at the time of the forensic evaluation he had a Full Scale IQ of 114. It would therefore appear that he did have some mild deficits when originally discharged from the hospital. While he reported having continual mental status changes at the time of the offense and even at the time of the forensic evaluation, it was not felt that these played a significant role in the commission of the offense. Comprehensive forensic evaluation suggested that psychological reactions to his illness and an underlying personality disorder were more direct contributors to the criminal acts. J was therefore recommended and ultimately found to be responsible for his behavior, according to the law.
authors.affiliation: Center for Forensic Psychiatry, Ann Arbor, Michigan, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Lemmen
authors.forename: C E
authors.initials: CE
authors.lastname: Holden
authors.forename: E P
authors.initials: EP
authors.lastname: Benedek
mesh_terms: D000328:Adult; D001554:Benzene / Q000009:adverse effects; D005104:Expert Testimony / Q000331:legislation & jurisprudence*; D006801:Humans; D007298:Insanity Defense; D016365:Liability, Legal; D008297:Male; D009784:Occupational Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology; D016273:Occupational Exposure / Q000009:adverse effects / Q000331:legislation & jurisprudence; D010348:Patient Care Team / Q000331:legislation & jurisprudence; D011605:Psychoses, Substance-Induced / Q000175:diagnosis* / Q000523:psychology; D012997:Solvents / Q000009:adverse effects*; D014050:Toluene / Q000009:adverse effects; D014241:Trichloroethylene / Q000009:adverse effects
chemical_list: D012997:Solvents; D014241:Trichloroethylene; D014050:Toluene; D001554:Benzene