Failure of hyperimmune plasma to prevent pneumonia caused by Rhodococcus equi in foals.
A trial was conducted on a Thoroughbred stud to determine whether or not the administration of anti-Rhodococcus equi hyperimmune plasma would reduce the prevalence of R equi pneumonia (rattles) in foals born in the 1992 horse breeding season. Hyperimmune plasma was administered to 34 foals; another 57 foals were untreated. There was no significant difference in the number of transfused foals developing R equi pneumonia compared with the untreated foals. The time required for recovery from pneumonia between the 2 groups was not significantly different.
Hurley
J R
JR
Scone Diagnostic Veterinary Laboratory, New South Wales.
Begg
A P
AP
D000193:Actinomycetales Infections / Q000276:immunology / Q000517:prevention & control / Q000662:veterinary*; D000818:Animals; D000831:Animals, Newborn; D000907:Antibodies, Bacterial / Q000032:analysis / Q000276:immunology / Q000627:therapeutic use*; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D006734:Horse Diseases / Q000453:epidemiology / Q000276:immunology / Q000517:prevention & control*; D006736:Horses; D007116:Immunization, Passive / Q000662:veterinary*; D007074:Immunoglobulin G / Q000032:analysis; D009517:New South Wales / Q000453:epidemiology; D015995:Prevalence; D016929:Rhodococcus equi / Q000276:immunology*
D000907:Antibodies, Bacterial; D007074:Immunoglobulin G