title: Intestinal adenocarcinoma with neuroendocrine cells in a clouded leopard (Neofelis nebulosa).
abstract: Adenocarcinoma of the small intestine was found in a 6-year-old clouded leopard. This tumour was characterized by the presence of goblet and neuroendocrine cells. The latter were labelled positively for either serotonin, somatostatin, neurotensin, gastrin or secretin. These neuroendocrine cells were reduced in number in most of the metastatic lesions, including those of the mesentery, diaphragmatic pleura, lungs, liver and heart, and squamous metaplasia was detected in some metastatic sites.
authors.affiliation: Kamikawa Livestock Hygiene Service Centre, Asahikawa, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Wada
authors.forename: H
authors.initials: H
authors.lastname: Kondo
authors.forename: G
authors.initials: G
authors.lastname: Bando
authors.forename: M
authors.initials: M
authors.lastname: Kosuge
authors.forename: Y
authors.initials: Y
authors.lastname: Ishikawa
authors.forename: K
authors.initials: K
authors.lastname: Kadota
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D001344:Autopsy / Q000662:veterinary; D002335:Carnivora; D004759:Enterochromaffin Cells / Q000473:pathology*; D007414:Intestinal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D007421:Intestine, Small / Q000737:chemistry / Q000473:pathology; D008168:Lung / Q000737:chemistry; D008297:Male; D008643:Mesentery / Q000737:chemistry / Q000473:pathology; D009206:Myocardium / Q000737:chemistry; D009479:Neuropeptides / Q000032:analysis*; D010994:Pleura / Q000737:chemistry; D012701:Serotonin / Q000032:analysis
chemical_list: D009479:Neuropeptides; D012701:Serotonin