title: Microscopical surgical management of cerebrospinal fluid rhinorrhoea with free grafts.
abstract: Iatrogenic cerebrospinal fluid (CSF) rhinorrhoea can occur after intranasal ethmoidectomy or removal of pituitary tumours using a transsphenoidal approach, and is categorized as intraoperative or post-operative according to the time of onset. From 1989 to 1992 at Severance Hospital, Seoul, Korea, we successfully repaired nine cases of CSF rhinorrhoea using fibrin-glue-coated fascia or inferior turbinate mucosa under a surgical microscope. Neither recurrent leaks nor post-operative complications were associated with the free graft. Our results indicate that repair of CSF rhinorrhoea using free grafts under a surgical microscope is as successful as using a local flap, and it is a simple and very effective method in managing CSF rhinorrhoea. The surgical technique is discussed in detail.
authors.affiliation: Department of Otorhinolaryngology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: J H
authors.initials: JH
authors.lastname: Yoon
authors.forename: J G
authors.initials: JG
authors.lastname: Lee
authors.forename: S H
authors.initials: SH
authors.lastname: Kim
authors.forename: I Y
authors.initials: IY
authors.lastname: Park
mesh_terms: D000328:Adult; D002559:Cerebrospinal Fluid Rhinorrhea / Q000601:surgery*; D005205:Fascia / Q000637:transplantation*; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008866:Microsurgery / Q000379:methods*; D008875:Middle Aged; D009297:Nasal Mucosa / Q000637:transplantation*
chemical_list: D015718:Fibrin Tissue Adhesive