title: Mineralogical characteristics of silica polymorphs in relation to their biological activities.
abstract: Numerous aspects of silica polymorphs can affect their biological activities, including periodic structures, compositional variations, dissolution characteristics, surface properties, and particle size and shape. For an understanding of mineral-induced pathogenesis from a mechanistic perspective, the links between these properties and biochemical processes must be elucidated. This paper presents some strategies for designing assays to evaluate these properties.
authors.affiliation: Geology and Geochemistry, Los Alamos National Laboratory, New Mexico 87545, USA.
authors.forename: G D
authors.initials: GD
authors.lastname: Guthrie
authors.forename: P J
authors.initials: PJ
authors.lastname: Heaney
mesh_terms: D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006801:Humans; D017655:Silicon Compounds / Q000737:chemistry / Q000378:metabolism; D012822:Silicon Dioxide / Q000737:chemistry / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D017655:Silicon Compounds; D012822:Silicon Dioxide