title: Cyclin dependent kinase activating kinases.
abstract: The cyclin dependent kinase activating kinase (CAK) has roles in both cell cycle regulation and transcription. CAK assembly is regulated either by additional protein binding or by phosphorylation. A recent comparison of this kinase from two yeast species shows that different proteins perform distinct roles and that the most studied CAK may function mainly in transcription.
authors.affiliation: Department of Biochemistry, Campus Box B121, University of Colorado Health Sciences Center, 4200 East Ninth Avenue, Denver, CO 80262, USA. Robert.Sclafani@UCHSC.edu
authors.forename: R A
authors.initials: RA
authors.lastname: Sclafani
mesh_terms: D000595:Amino Acid Sequence; D002455:Cell Division / Q000502:physiology; D002477:Cells / Q000166:cytology* / Q000201:enzymology*; D018844:Cyclin-Dependent Kinases / Q000378:metabolism*; D008969:Molecular Sequence Data; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D000095043:Cyclin-Dependent Kinase-Activating Kinase
chemical_list: D017346:Protein Serine-Threonine Kinases; D018844:Cyclin-Dependent Kinases; D000095043:Cyclin-Dependent Kinase-Activating Kinase