title: [Intermediate and long-term outcome after percutaneous balloon dilatation of valvular pulmonary stenoses in childhood].
abstract: Pulmonary balloon valvuloplasty was performed in 52 patients aged 7 days to 19 years (mean 5.5 years). Mean balloon/anulus ratio was 1.24. Mean right ventricular outflow tract (RVOT) systolic pressure gradient was 79.9 +/- 37.3 (x +/- SD) mm Hg before valvuloplasty and 37.2 +/- 29.6 mm Hg (p < 0.001) immediately after the procedure. 33 patients had residual RVOT-gradient < or = 36 (22 +/- 7) mm Hg, 19 patients had gradients > 36 (67.1 +/- 35.6) mm Hg. During intermediate follow-up (< 2 years) RVOT gradient assessed by catheterization or Doppler echocardiography improved without any additional intervention in 10/19 patients with RVOT gradient > 36 mm Hg early after valvuloplasty. 6/19 patients required additional reduction of RVOT gradient by repeated valvuloplasty (51 +/- 19 to 29 +/- 5 mm Hg; p < 0.01). 3/19 patients needed surgical resection of extremely thickened dysplastic valves. 49 patients had a mid- to long-term follow-up by echocardiography (mean 4.3, max. 9 years); the RVOT gradient decreased from 25.7 +/- 12.8 mm Hg during intermediate follow-up to 18.0 +/- 7.0 mm Hg during long-term follow-up. If pulmonary regurgitation was present after dilatation (n = 38), it was hemodynamically not significant and did not change during follow-up. Percutaneous balloon valvuloplasty was a safe and effective treatment for pulmonary valve stenosis in infancy and childhood. Long-term results confirm the value of this method.
authors.affiliation: Abteilung Kinderheilkunde III, Medizinische Hochschule Hannover.
authors.forename: B
authors.initials: B
authors.lastname: Mahnert
authors.forename: T
authors.initials: T
authors.lastname: Paul
authors.forename: I
authors.initials: I
authors.lastname: Luhmer
authors.forename: H C
authors.initials: HC
authors.lastname: Kallfelz
mesh_terms: D000293:Adolescent; D000328:Adult; D006328:Cardiac Catheterization; D002404:Catheterization; D002648:Child; D002675:Child, Preschool; D015150:Echocardiography, Doppler; D005260:Female; D005500:Follow-Up Studies; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011662:Pulmonary Subvalvular Stenosis / Q000151:congenital / Q000503:physiopathology / Q000628:therapy; D011664:Pulmonary Valve / Q000002:abnormalities / Q000503:physiopathology; D011666:Pulmonary Valve Stenosis / Q000151:congenital* / Q000503:physiopathology / Q000628:therapy; D016896:Treatment Outcome