title: Recurrent histiocytic necrotizing lymphadenitis (Kikuchi's disease) in an human T lymphotropic virus type I carrier.
abstract: We describe a case of recurrent histiocytic necrotizing lymphadenitis (HNL) with aseptic meningitis. The patient was a 46-year-old male and a carrier of human T lymphotropic virus type I (HTLV-I). The patient had a past medical history of at least three relapses of HNL. In addition, his sister, who was also an HTLV-I carrier, had recurrent clinical episodes consistent with those of HNL, suggesting familial HNL occurrence. This observation suggests the possibility that HTLV-I infection is relevant to the pathogenesis of HNL.
authors.affiliation: Department of Internal Medicine, Hiratsuka Kyosai Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Atarashi
authors.forename: N
authors.initials: N
authors.lastname: Yoshimura
authors.forename: H
authors.initials: H
authors.lastname: Nodera
authors.forename: K
authors.initials: K
authors.lastname: Tsukimoto
authors.forename: H
authors.initials: H
authors.lastname: Beppu
authors.forename: M
authors.initials: M
authors.lastname: Kanayama
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D016827:CD8 Antigens / Q000276:immunology; D002353:Carrier State / Q000821:virology*; D002455:Cell Division; D017809:Fatal Outcome; D015490:HTLV-I Infections / Q000150:complications*; D006566:Herpesviridae Infections / Q000150:complications; D015654:Herpesvirus 6, Human / Q000276:immunology; D006644:Histiocytes / Q000276:immunology / Q000473:pathology*; D015368:Human T-lymphotropic virus 1; D006801:Humans; D007150:Immunohistochemistry; D016256:Lewis X Antigen / Q000276:immunology; D008199:Lymphadenitis / Q000209:etiology* / Q000235:genetics / Q000473:pathology; D008297:Male; D008582:Meningitis, Aseptic / Q000150:complications; D008875:Middle Aged; D009336:Necrosis; D010375:Pedigree; D012008:Recurrence
chemical_list: D000914:Antibodies, Viral; D016827:CD8 Antigens; D016256:Lewis X Antigen