[Immuno-hemolytic transfusion reactions. III. Report of 61 cases].
Blood transfusion is mainly bound to immunological and infectious risks. The immunological risk originates from an incompatibility between the blood of the donor and that of the recipient; this risk remains insufficiently assessed. A multicentre study has been carried out by the French Blood Transfusion Society and the National Institute for Blood Transfusion. Sixty-one accidents due to an erythrocyte incompatibility were found: 26 cases with ABO incompatibility, and 35 cases with alloantibodies of other blood group systems. For the former category of accidents, the most frequent cause was due to a failure in the realization of the bedside ABO check. For the latter, the main problem was the achievement and the interpretation of antibody screening. The long term follow-up shows no chronic after-effects of immunological accidents. For each accident, errors have been identified and analysed. It was proven that they all originate from health care establishments.
Le Pennec
P Y
PY
Centre National de Référence pour les Groupes Sanguins, Institut National de la Transfusion Sanguine, Paris, France.
Tissier
A M
AM
Mannessier
L
L
Agulles
O
O
Babinet
J
J
Bidet
M L
ML
Bombail-Girard
D
D
Cabaud
J J
JJ
Cartron
J
J
Chiaroni
J
J
Desaint
C
C
Krause
C
C
Lamy
B
B
Meyer
F
F
Mortelecque
R
R
Nafissi
S
S
Rasongles
P
P
Schweitzer
B
B
Rouger
P
P
D000017:ABO Blood-Group System / Q000276:immunology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001787:Blood Group Incompatibility; D001793:Blood Preservation; D019411:Clinical Laboratory Techniques; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007518:Isoantibodies / Q000097:blood; D008297:Male; D019300:Medical Errors; D008875:Middle Aged; D018570:Risk Assessment; D065227:Transfusion Reaction
D000017:ABO Blood-Group System; D007518:Isoantibodies