title: Quality and authenticity of heterologous proteins synthesized in yeast.
abstract: Yeast, especially Saccharomyces cerevisiae and Pichia pastoris, are major hosts employed in the expression of authentic heterologous proteins of high quality in the biopharmaceutical, industrial and academic environments. There has been recent progress in characterizing and controlling the factors involved in determining authenticity.
authors.affiliation: Preclinical Research, Bayer Corporation, 800 Dwight Way, Berkeley, CA 94701-1986, USA. meckart@ix.netcom.com
authors.forename: M R
authors.initials: MR
authors.lastname: Eckart
authors.forename: C M
authors.initials: CM
authors.lastname: Bussineau
mesh_terms: D001709:Biotechnology; D015870:Gene Expression; D006031:Glycosylation; D014176:Protein Biosynthesis; D017510:Protein Folding; D011499:Protein Processing, Post-Translational; D011994:Recombinant Proteins / Q000096:biosynthesis* / Q000737:chemistry / Q000235:genetics*; D015003:Yeasts / Q000235:genetics* / Q000378:metabolism*
chemical_list: D011994:Recombinant Proteins