Influence of experimental hypercholesterolemia on the monoamine oxidase activity in rabbit arteries.
Using a model of experimental atherogenesis in New Zealand rabbits we found a lower noradrenaline level in the aorta than in the femoral artery. The activity of monoamine oxidase was decreased in the femoral artery and increased in the aorta of the cholesterol-fed animals when compared with controls.
Caramona
M M
MM
Laboratory of Pharmacology, Faculty of Pharmacy, University of Coimbra, Portugal.
Cotrim
M D
MD
Figueiredo
I V
IV
Tavares
P
P
Ribeiro
C A
CA
Beja
M L
ML
Wulfroth
P
P
Teixeira
F
F
D000818:Animals; D001011:Aorta / Q000201:enzymology; D005263:Femoral Artery / Q000201:enzymology; D006937:Hypercholesterolemia / Q000201:enzymology*; D008297:Male; D008995:Monoamine Oxidase / Q000378:metabolism*; D009638:Norepinephrine / Q000032:analysis; D011817:Rabbits
D008995:Monoamine Oxidase; D009638:Norepinephrine