Growth deficits in ADHD children revisited: evidence for disorder-associated growth delays?
OBJECTIVE
To reevaluate the hypothesis that stimulants cause growth deficits in children with attention-deficit hyperactivity disorder (ADHD).


METHODS
Growth deficits in height and weight were examined in 124 children and adolescents with ADHD and 109 controls, using appropriate correction by age and parental height measures and attending to issues of pubertal stage, treatment, and psychiatric comorbidity.


RESULTS
Small but significant differences in height were identified between ADHD children and controls. However, height deficits were evident in early but not late adolescent ADHD children and were unrelated to use of psychotropic medications. There was no evidence of weight deficits in ADHD children relative to controls, and no relationship between measures of malnutrition and short stature was identified.


CONCLUSIONS
ADHD may be associated with temporary deficits in growth in height through mid-adolescence that may normalize by late adolescence. This effect appears to be mediated by ADHD and not its treatment.
Spencer
T J
TJ
Pediatric Psychopharmacology Unit (ACC 725), Massachusetts General Hospital, Boston 02114, USA.
Biederman
J
J
Harding
M
M
O'Donnell
D
D
Faraone
S V
SV
Wilens
T E
TE
D000293:Adolescent; D001289:Attention Deficit Disorder with Hyperactivity / Q000188:drug therapy*; D001827:Body Height / Q000187:drug effects*; D001835:Body Weight / Q000187:drug effects*; D000697:Central Nervous System Stimulants / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D004392:Dwarfism / Q000139:chemically induced*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008774:Methylphenidate / Q000009:adverse effects* / Q000627:therapeutic use
D000697:Central Nervous System Stimulants; D008774:Methylphenidate