[Status of the renal arterial system in experimental aortic coarctation and after its repair].
Structural changes of kidney arteries and glomeruli are studied histologically, histochemically and morphometrically in 10 dogs with a hemodynamic model of aorta coarctation, 10 dogs with a corrected defect and 10 control dogs. Decrease of the blood inflow is followed by the development of adaptive, compensatory and pathological vascular changes in the kidney. The first type of changes manifested in the media circular muscles atrophy of the kidney arteries, the second type of changes is a vessel restructuring with formation of blocking arteries. The third is sclerosis of the arterial branches and glomeruli. Surgical removal of the experimental defect is followed by a reverse development of these processes, particularly that of circular muscles atrophy of the vascular wall. Reversibility of compensatory and solerotic changes of arteries and glomeruli proceeds much slower.
Shormanov
S V
SV
Ial'tsev
A V
AV
D000818:Animals; D001017:Aortic Coarctation / Q000209:etiology / Q000473:pathology* / Q000601:surgery; D001158:Arteries / Q000473:pathology; D001160:Arterioles / Q000473:pathology; D004195:Disease Models, Animal; D004285:Dogs; D006439:Hemodynamics / Q000502:physiology*; D006651:Histocytochemistry; D007668:Kidney / Q000098:blood supply*; D007678:Kidney Glomerulus / Q000098:blood supply*; D009131:Muscle, Smooth, Vascular / Q000473:pathology; D012598:Sclerosis