title: Phyllodes tumor in epileptics: a report of two cases.
abstract: Phyllodes tumor is an uncommon breast neoplasm characterized by a proliferation of both stromal and epithelial elements. In 1989, two young patients with phyllodes tumors were referred to our surgical department because of the detection of breast lumps. Interestingly, both patients also had epilepsy and had been taking anticonvulsants. An analytical case control study revealed that no significant difference between the control group and phyllodes group was found for various categories. In addition, no anticonvulsant medication had been prescribed in either the control group or the phyllodes group except for these two cases. We herein report two cases of phyllodes tumors occurring in two young epileptic patients.
authors.affiliation: Department of Surgical Oncology, Osaka University Medical School, Suita City, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Shiba
authors.forename: M
authors.initials: M
authors.lastname: Sakon
authors.forename: J I
authors.initials: JI
authors.lastname: Kambayashi
authors.forename: T
authors.initials: T
authors.lastname: Takeda
authors.forename: T
authors.initials: T
authors.lastname: Kobayashi
authors.forename: H
authors.initials: H
authors.lastname: Yoshimura
authors.forename: S I
authors.initials: SI
authors.lastname: Takai
mesh_terms: D000293:Adolescent; D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D001707:Biopsy, Needle; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D004359:Drug Therapy, Combination; D017034:Epilepsy, Frontal Lobe / Q000188:drug therapy*; D004830:Epilepsy, Tonic-Clonic / Q000188:drug therapy*; D005260:Female; D006801:Humans; D015412:Mastectomy, Segmental; D009378:Neoplasms, Multiple Primary / Q000139:chemically induced / Q000473:pathology / Q000601:surgery; D003557:Phyllodes Tumor / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D012307:Risk Factors
chemical_list: D000927:Anticonvulsants