title: Hemodynamic and clinical improvement after superficial vein ablation in primary combined venous insufficiency with ulceration.
abstract: OBJECTIVE
  This study was undertaken to determine the degree of clinical and hemodynamic improvement after surgical ablation of incompetent superficial and perforator veins in limbs with combined deep and superficial venous incompetence manifested by chronic dermal ulceration.
  
  
  METHODS
  Eleven limbs in 10 patients with class 5 or 6 venous insufficiency (ulceration) were assessed by CEAP (clinical, etiologic, anatomic, pathophysiologic) clinical scores, air plethysmography, color duplex ultrasonography, and phlebography (both ascending and descending). Surgical ablation of superficial and perforating veins was performed, followed by repeat clinical, air plethysmographic, and color duplex ultrasonographic examinations.
  
  
  RESULTS
  All 11 limbs had combined deep and superficial vein reflux on the preoperative color duplex ultrasound scan. Clinical symptom scores decreased from 10 to 1.4 after operation. Postoperative air plethysmography demonstrated significant reduction in reflux as measured by the mean venous filling index, which decreased from 12 +/- 5 ml/sec to 2.7 +/- 1 ml/sec after surgery. Calf pump function was also significantly improved, with a mean ejection fraction that increased from 43% +/- 11 to 59% +/- 13 and mean residual volume fraction that decreased from 56% +/- 15 to 33% +/- 16. Each of these measures was significantly different from the preoperative value (p < 0.05). Similar improvement characterized subgroups of limbs with three or more incompetent deep segments (n = 6) or popliteal segment incompetence (n = 6).
  
  
  CONCLUSIONS
  Superficial and perforating vein incompetence accounts for a substantial and correctable component of venous insufficiency in limbs with combined deep and superficial vein reflux and venous ulceration. These data indicate that surgical correction of this component significantly improves clinical symptoms and venous hemodynamics. Superficial and perforator ablation is an appropriate initial step in the management of combined deep and superficial venous incompetence.
authors.affiliation: Section of Vascular Surgery, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, USA.
authors.forename: F T
authors.initials: FT
authors.lastname: Padberg
authors.forename: P J
authors.initials: PJ
authors.lastname: Pappas
authors.forename: C T
authors.initials: CT
authors.lastname: Araki
authors.forename: T L
authors.initials: TL
authors.lastname: Back
authors.forename: R W
authors.initials: RW
authors.lastname: Hobson
mesh_terms: D000368:Aged; D000388:Air; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D010991:Plethysmography; D011184:Postoperative Period; D018615:Ultrasonography, Doppler, Color; D014647:Varicose Ulcer / Q000145:classification / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery; D014680:Veins / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D014689:Venous Insufficiency / Q000145:classification / Q000175:diagnosis / Q000503:physiopathology* / Q000601:surgery