Early experience with inhaled nitric oxide for the treatment of infants and children with pulmonary hypertension.
When nitric oxide (NO), an endogenous regulator of smooth muscle tone, is administered by inhalation, it acts as a selective pulmonary vasodilator. This report details the treatment with inhaled NO of the first 11 patients in Hawaii.
Easa
D
D
Department of Pediatrics, Kapiolani Medical Center for Women and Children, Honolulu, HI 96826, USA.
Murai
D T
DT
Oka
B
B
Dressel
M
M
Vanderford
P
P
Pelke
S
S
Balaraman
V
V
D000280:Administration, Inhalation; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000209:etiology / Q000401:mortality; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009569:Nitric Oxide / Q000008:administration & dosage*; D011651:Pulmonary Artery / Q000187:drug effects; D015996:Survival Rate; D014664:Vasodilation / Q000187:drug effects
D009569:Nitric Oxide