[Evaluation of antibacterial and antitoxic activity of normal human immunoglobulin for intravenous use (IVIG)].
In the present study, human immunoglobulins for intravenous use (IVIG), were tested for contents of diphtheria antibodies, antistreptolysin O, antistaphylolysin and antibody level of endotoxin of B. pertussis, enterobacterial common antigen and group B Streptococci. It was shown that all examined immunoglobulin preparation contained antibodies against all tested antigens. Our investigation revealed differences between IVIG preparations and IVIG lots. Basing on these results, we know that the biological activity of Bioglobulin is the same as biological activity of other IVIG preparations produced by foreign manufactures.
Bucholc
B
B
Zakład Badania Surowic i Szczepionek PZH w Warszawie.
Banach
W
W
Wysokińska
T
T
Cieślik
A
A
Chodorowska
M
M
D000907:Antibodies, Bacterial / Q000032:analysis*; D000942:Antigens, Bacterial / Q000032:analysis; D000989:Antistreptolysin / Q000032:analysis; D004165:Diphtheria / Q000276:immunology; D004731:Endotoxins / Q000276:immunology; D004755:Enterobacteriaceae / Q000276:immunology; D006460:Hemolysin Proteins / Q000032:analysis; D006801:Humans; D007136:Immunoglobulins; D016756:Immunoglobulins, Intravenous / Q000032:analysis* / Q000592:standards; D015203:Reproducibility of Results; D013292:Streptococcus agalactiae / Q000276:immunology
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D004731:Endotoxins; D006460:Hemolysin Proteins; D007136:Immunoglobulins; D016756:Immunoglobulins, Intravenous; C006603:antistaphylolysin; C017286:enterobacterial common antigen; D000989:Antistreptolysin