title: Astonishing fertility from a single oocyte recovery.
abstract: A 36 year old patient underwent in-vitro fertilization (IVF) and embryo transfer. Three embryos were transferred to her uterus and eight spare embryos were cryopreserved. The patient conceived a quadruplet pregnancy and delivered two boys and two identical twin girls by Caesarean section at 30 weeks gestation. The couple subsequently donated their cryopreserved embryos to the embryo donation programme for the use of other couples. Two agonadal patients received these cryopreserved-thawed embryos, each in a hormone replacement cycle. Both conceived, one has safely delivered twins and the other conceived a twin pregnancy, one of the fetuses has vanished and the other is progressing normally. The overall embryo implantation rate was seven out of nine (78%).
authors.affiliation: Bourn Hall Clinic, Cambridge, UK.
authors.forename: S F
authors.initials: SF
authors.lastname: Marcus
authors.forename: N K
authors.initials: NK
authors.lastname: Marcus
authors.forename: P R
authors.initials: PR
authors.lastname: Brinsden
mesh_terms: D000328:Adult; D015925:Cryopreservation; D005260:Female; D005298:Fertility; D005307:Fertilization in Vitro; D006801:Humans; D018587:Oocyte Donation; D011247:Pregnancy; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple; D011783:Quadruplets; D014427:Twins