Antibiotic resistance: counting the cost.
Acquisition of drug resistance should impose a cost on bacteria. Recent studies, however, suggest that natural selection acts to reduce, or eliminate, the growth disadvantage of resistant bacteria, making it difficult to reverse the high levels of antibiotic resistance currently found in hospitals and the community.
Spratt
B G
BG
Molecular Microbiology Group, School of Biological Sciences, University of Sussex, Brighton, UK.
D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D004352:Drug Resistance, Microbial; D006761:Hospitals; D006801:Humans; D012641:Selection, Genetic
D000900:Anti-Bacterial Agents