An unusual cause for collapse in a patient with arthritis.
We present the clinical case of a patient who was admitted to the intensive care ward with severe central nervous system symptoms and cardiovascular collapse within a week of starting sulphasalazine; in the absence of any other diagnosis, these symptoms were felt to be due to a previously unreported adverse effect of sulphasalazine.
Heath
K J
KJ
Department of Anaesthesia, Addenbrooke's Hospital, Cambridge, UK.
Sampson
M J
MJ
Ridley
S A
SA
D000368:Aged; D018501:Antirheumatic Agents / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D003422:Critical Care; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D012640:Seizures / Q000139:chemically induced* / Q000175:diagnosis; D012769:Shock / Q000139:chemically induced* / Q000175:diagnosis; D012460:Sulfasalazine / Q000009:adverse effects*; D018487:Ventricular Dysfunction, Left / Q000139:chemically induced* / Q000175:diagnosis
D018501:Antirheumatic Agents; D012460:Sulfasalazine