title: Early experience with inhaled nitric oxide for the treatment of infants and children with pulmonary hypertension.
abstract: When nitric oxide (NO), an endogenous regulator of smooth muscle tone, is administered by inhalation, it acts as a selective pulmonary vasodilator. This report details the treatment with inhaled NO of the first 11 patients in Hawaii.
authors.affiliation: Department of Pediatrics, Kapiolani Medical Center for Women and Children, Honolulu, HI 96826, USA.
authors.forename: D
authors.initials: D
authors.lastname: Easa
authors.forename: D T
authors.initials: DT
authors.lastname: Murai
authors.forename: B
authors.initials: B
authors.lastname: Oka
authors.forename: M
authors.initials: M
authors.lastname: Dressel
authors.forename: P
authors.initials: P
authors.lastname: Vanderford
authors.forename: S
authors.initials: S
authors.lastname: Pelke
authors.forename: V
authors.initials: V
authors.lastname: Balaraman
mesh_terms: D000280:Administration, Inhalation; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000209:etiology / Q000401:mortality; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009569:Nitric Oxide / Q000008:administration & dosage*; D011651:Pulmonary Artery / Q000187:drug effects; D015996:Survival Rate; D014664:Vasodilation / Q000187:drug effects
chemical_list: D009569:Nitric Oxide