Intracellular free calcium and its modulation.
Over the past six years, Ca2+ channels have continued to receive much attention, partly as a result of their biological importance as excitation-response transducers, and partly as a result of exciting developments in enlightening their molecular properties and cellular functions. Neurotransmitter release, neurosecretion, neuronal excitation, survival of neurons, and many other neuronal functions are controlled by the cellular [Ca2+]. In turn the rise in [Ca2+]i modulates specific cellular functions. The enhancement of [Ca2+]i is modulated by various factors, peptidergic and not.
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Dipartimento di Fisiologia e Biochimica G. Moruzzi, Università di Pisa, Italy.
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D015220:Calcium Channels / Q000378:metabolism / Q000502:physiology; D004594:Electrophysiology; D006801:Humans; D007425:Intracellular Membranes / Q000378:metabolism*; D011956:Receptors, Cell Surface / Q000502:physiology
D015220:Calcium Channels; D011956:Receptors, Cell Surface; D002118:Calcium