title: Oligomenorrhea treatment by purified FSH using a fixed protocol.
abstract: This study is designed to evaluate the effectiveness, safety and tolerability of a low dose of purified FSH administration using a fixed protocol in oligomenorrheic patients not desiring pregnancy. We used a low dose (75 IU/day for 5 days) of purified FSH (Metrodin) in 10 oligomenorrheic patients (aged 18-30) for 25 cycles. The onset of menstruation occurred in 7 patients (70%) and in 19 treatment cycles (76%), the ovulation was verified in 5 of these patients (50%) for 13 cycles (52%). One patient had spotting after the treatment, 2 patients did not have any response. The treatment did not cause side effects and it showed a good tolerability.
authors.affiliation: Institute of Obstetrics and Gynecology, University of Sassari, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Dessole
authors.forename: E
authors.initials: E
authors.lastname: Coccollone
authors.forename: G
authors.initials: G
authors.lastname: Ambrosini
authors.forename: D
authors.initials: D
authors.lastname: D'Antona
authors.forename: N
authors.initials: N
authors.lastname: Vargiu
authors.forename: P L
authors.initials: PL
authors.lastname: Cherchi
mesh_terms: D000328:Adult; D004334:Drug Administration Schedule; D005260:Female; D005640:Follicle Stimulating Hormone / Q000627:therapeutic use*; D006728:Hormones / Q000097:blood; D006801:Humans; D009839:Oligomenorrhea / Q000097:blood / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D006728:Hormones; D005640:Follicle Stimulating Hormone