title: Imaging red blood cells with the atomic force microscope.
abstract: A novel technique for the reproduction of ultramorphological images and details of the surface of normal and pathological red blood cells (RBC) was investigated. The atomic force microscope (AFM) provided high-resolution images of cell surfaces. The RBC dimensions obtained by this technique revealed differences between native red cells in smears and glutaraldehyde-fixed red cells. It was shown that fixed red blood cells were best suited for the ultramorphological imaging of the cell surface.
authors.affiliation: CRUH, Clinical Research Unit Haematology, Katholieke Universiteit Leuven, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Zachée
authors.forename: J
authors.initials: J
authors.lastname: Snauwaert
authors.forename: P
authors.initials: P
authors.lastname: Vandenberghe
authors.forename: L
authors.initials: L
authors.lastname: Hellemans
authors.forename: M
authors.initials: M
authors.lastname: Boogaerts
mesh_terms: D004912:Erythrocytes / Q000648:ultrastructure*; D006801:Humans; D018625:Microscopy, Atomic Force / Q000379:methods*