title: Synthesis and antibacterial testing of some new quinolines, pyridazinoquinolines and spiroindoloquinolines.
abstract: 3-Dicyanomethylideneindole derivatives were involved in (i) ring expansion reactions in alcoholic piperidine to form new quinolines from which a new pyridazinoquinoline was synthesised; and (ii) formation of new spiroindoloquinolines by reactions with cyclohexanone and beta-tetralone. The suggested structures of the new products were confirmed by IR, 1H-NMR, 13C-NMR and mass spectral analyses. Some of the new derivatives were active against the bacteria Escherichia cell.
authors.affiliation: Chemistry Department, Faculty of Science at Mansoura, Egypt.
authors.forename: A A
authors.initials: AA
authors.lastname: el-Ahl
authors.forename: M M
authors.initials: MM
authors.lastname: Mashaly
authors.forename: M A
authors.initials: MA
authors.lastname: Metwally
mesh_terms: D042462:4-Quinolones; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects*; D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D011724:Pyridazines / Q000138:chemical synthesis* / Q000494:pharmacology; D011804:Quinolines / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D042462:4-Quinolones; D000890:Anti-Infective Agents; D007211:Indoles; D011724:Pyridazines; D011804:Quinolines