Proliferative glomerulonephritis revealing chronic Q fever.
We describe the case of a 69-year-old male with a year-long history of renal failure. Investigation revealed proliferative glomerulonephritis, cryoglobulinemia, and Q fever endocarditis. Renal tissue examination for the presence of Coxiella burnetii was positive. The patient was treated by doxycycline and chloroquine; his clinical status, renal failure, and chronic Q fever have dramatically improved.
Vacher-Coponat
H
H
Service de Nephrologie et Hemodialyse, Hopital Sainte-Marguerite, Marseille, France.
Dussol
B
B
Raoult
D
D
Casanova
P
P
Berland
Y
Y
D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002738:Chloroquine / Q000627:therapeutic use; D002908:Chronic Disease; D016997:Coxiella burnetii / Q000187:drug effects / Q000302:isolation & purification; D003449:Cryoglobulinemia / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D004318:Doxycycline / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D015432:Glomerulonephritis, Membranoproliferative / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000382:microbiology / Q000473:pathology; D008297:Male; D011778:Q Fever / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology
D000900:Anti-Bacterial Agents; D002738:Chloroquine; D004318:Doxycycline