Efficacy of dietary and injected vitamin E for poults.
An experiment was conducted to compare the efficacy of two dietary sources and an injectable form of vitamin E (VE) to improve the VE status of poults. Six of the treatments consisted of a factorial arrangement of three concentrations and two sources of dietary VE. Turkeys in these treatments received 12, 80, or 150 IU of either dl-alpha-tocopheryl acetate or d-alpha-tocopherol (d-alpha-TOC)/kg of diet. The seventh treatment consisted of a single subcutaneous injection of d-alpha-TOC at 1 d of age. Poults in this treatment were subcutaneously injected in the dorsal area of the neck with 25 IU of d-alpha-TOC, this amount being approximately equivalent to the amount poults would consume if their diet was supplemented with 150 IU of VE/kg during their 1st wk of life. Concentration, source, or route of VE administration did not affect growth parameters, plasma creatine kinase, plasma triglycerides, or liver lipid peroxidation as measured by the thiobarbituric acid reactive substances assay (TBARS). Plasma, red blood cells (RBC), and liver alpha-TOC decreased from hatching to 14 d of age in poults fed either source of VE. The use of 80 or 150 IU of dietary VE (either source) reduced (P < 0.05) the extent of depletion of alpha-TOC at all ages and also reduced the susceptibility of RBC to hemolysis. There was no effect of source of dietary VE on concentration of alpha-TOC in plasma, RBC, or liver, or on RBC hemolysis. Subcutaneous injection of 25 IU of d-alpha-TOC at Day 1 increased (P < 0.05) alpha-TOC concentration until 7 d of age. Also, d-alpha-TOC injection reduced (P < 0.05) RBC susceptibility to hemolysis through 21 d of age. Data showed that one single subcutaneous injection of 25 IU of d-alpha-TOC at 1 d of age was as effective as 80 IU or more of dietary VE through 21 d to improve the alpha-TOC status of poults.
Soto-Salanova
M F
MF
Department of Animal Science, Iowa State University, Ames 50011-3150, USA.
Sell
J L
JL
D000284:Administration, Oral; D000818:Animals; D001835:Body Weight / Q000502:physiology; D003402:Creatine Kinase / Q000502:physiology; D004032:Diet / Q000592:standards / Q000662:veterinary*; D004305:Dose-Response Relationship, Drug; D004912:Erythrocytes / Q000737:chemistry; D007279:Injections, Subcutaneous / Q000662:veterinary; D008297:Male; D011897:Random Allocation; D013025:Glycine max / Q000592:standards; D013997:Time Factors; D014280:Triglycerides / Q000097:blood; D014422:Turkeys / Q000097:blood* / Q000502:physiology; D014810:Vitamin E / Q000008:administration & dosage* / Q000032:analysis / Q000494:pharmacology*; D003313:Zea mays / Q000592:standards
D014280:Triglycerides; D014810:Vitamin E; D003402:Creatine Kinase