title: Numerous members of the Sox family of HMG box-containing genes are expressed in developing mouse teeth.
abstract: We used RT-PCR to detect the expression in mouse molar and incisor tooth germs of 14 of the 19 known members of the Sox family of HMG box-containing transcription factors. These sequences fell into all 6 of the main subdivisions of the Sox family. In general, the relative transcript abundance of the different Sox genes is similar between molar and incisor tooth germs, although 3 low-abundance transcripts were found in only a single tooth type. The expression of Sox genes during tooth development has not been reported previously and further experiments will be required to determine their role in this process.
authors.affiliation: Department of Anthropology, Pennsylvania State University, University Park 16802, USA. dws10@psuvm.psu.edu
authors.forename: D W
authors.initials: DW
authors.lastname: Stock
authors.forename: A V
authors.initials: AV
authors.lastname: Buchanan
authors.forename: Z
authors.initials: Z
authors.lastname: Zhao
authors.forename: K M
authors.initials: KM
authors.lastname: Weiss
mesh_terms: D000818:Animals; D015870:Gene Expression; D006609:High Mobility Group Proteins / Q000145:classification / Q000235:genetics*; D051379:Mice; D008969:Molecular Sequence Data; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D014070:Tooth / Q000196:embryology / Q000378:metabolism*
chemical_list: D006609:High Mobility Group Proteins