title: A novel inhibitor of platelet aggregation from the Cyanophyceae Oscillatoria rosea (NIES-208)
abstract: (2S)-1-O-Palmitoleyl-3-O-beta-D-galactopyranosylglycerol was isolated from the marine alga Oscillatoria rosea. It caused a concentration-dependent inhibition of platelet aggregation induced by U46619. Its structure was elucidated by spectroscopic analysis and chemical evidence.
authors.forename: M C
authors.initials: MC
authors.lastname: Rho
authors.forename: K
authors.initials: K
authors.lastname: Matsunaga
authors.forename: K
authors.initials: K
authors.lastname: Yasuda
authors.forename: Y
authors.initials: Y
authors.lastname: Ohizumi
mesh_terms: D019796:15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; D001792:Blood Platelets / Q000187:drug effects / Q000502:physiology; D000458:Cyanobacteria; D005697:Galactosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000302:isolation & purification* / Q000494:pharmacology; D011450:Prostaglandin Endoperoxides, Synthetic / Q000494:pharmacology; D013928:Thromboxane A2 / Q000031:analogs & derivatives / Q000494:pharmacology; D014662:Vasoconstrictor Agents / Q000494:pharmacology
chemical_list: C102720:1-O-palmitoyl-3-galactopyranosylglycerol; D005697:Galactosides; D010975:Platelet Aggregation Inhibitors; D011450:Prostaglandin Endoperoxides, Synthetic; D014662:Vasoconstrictor Agents; D013928:Thromboxane A2; D019796:15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid