[Induction of multiple melanocytic nevus cell nevi in 2 children with malignant hematologic systemic diseases and chemotherapy-induced immunosuppression].
Two children developed multiple melanocytic naevi after polychemotherapy administered for acute lymphoblastic leukaemia in one and for non-Hodgkin lymphoma in the other. Induction of naevi does not seem to be related to specific agents used in chemotherapy, but rather to the immunosuppression resulting from multiple-agent chemotherapy. There are reports in the literature of both intrinsically and iatrogenically immunosuppressed patients who have developed multiple melanocytic naevi.
Jappe
U
U
Hautklinik, Universitäts-Krankenhaus, Eppendorf.
Abeck
D
D
Janka-Schaub
G E
GE
Gross
G
G
Jakob
T
T
Ring
J
J
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D005260:Female; D006801:Humans; D007108:Immune Tolerance / Q000187:drug effects / Q000276:immunology; D016399:Lymphoma, T-Cell / Q000188:drug therapy* / Q000276:immunology; D008297:Male; D009508:Nevus, Pigmented / Q000139:chemically induced* / Q000276:immunology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy* / Q000276:immunology; D012878:Skin Neoplasms / Q000139:chemically induced* / Q000276:immunology