title: Searching for signals: mortality and cardiovascular events in published randomized control trials of nifedipine in ischemic heart disease and hypertension.
abstract: META-ANALYSIS: A meta-analysis of published randomized control trials of nifedipine in hypertension and stable angina pectoris was performed.
  
  
  RESULTS
  The results suggest a formulation-dependent increased risk of mortality and adverse cardiovascular outcomes for monotherapy use in patients with stable angina pectoris. No increased risk was seen in the hypertension studies.
authors.affiliation: Harvard School of Public Health, Boston, USA.
authors.forename: W
authors.initials: W
authors.lastname: Stason
authors.forename: C H
authors.initials: CH
authors.lastname: Schmid
authors.forename: J F
authors.initials: JF
authors.lastname: Caubet
authors.forename: B
authors.initials: B
authors.lastname: Kupelnick
authors.forename: D
authors.initials: D
authors.lastname: Cory
authors.forename: G
authors.initials: G
authors.lastname: Whiting
authors.forename: T C
authors.initials: TC
authors.lastname: Chalmers
authors.forename: S D
authors.initials: SD
authors.lastname: Ross
mesh_terms: D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000401:mortality / Q000503:physiopathology; D017202:Myocardial Ischemia / Q000188:drug therapy* / Q000401:mortality / Q000503:physiopathology; D009543:Nifedipine / Q000627:therapeutic use*; D016032:Randomized Controlled Trials as Topic; D014665:Vasodilator Agents / Q000627:therapeutic use*
chemical_list: D014665:Vasodilator Agents; D009543:Nifedipine