title: Mitochondrial cytochrome C oxidase subunit I of Manduca sexta and a comparison with other invertebrate genes.
abstract: A cDNA encoding mitochondrial cytochrome c oxidase subunit I (mt COI) from Manduca sexta (Lepidoptera: Sphingidae) was cloned and sequenced. AT (adenine-thymine) content is high and codon usage is biased and likely reflects the role of mt COI in electron transport. The encoded protein is 514 amino acids long, contains seven invariant His residues observed in COIs in all organisms and would be predicted to be composed of 12 transmembrane regions.
authors.affiliation: Department of Biochemistry, University of Arizona, Tucson 85721, USA.
authors.forename: D R
authors.initials: DR
authors.lastname: Frohlich
authors.forename: B A
authors.initials: BA
authors.lastname: Stevenson
authors.forename: A M
authors.initials: AM
authors.lastname: Peterson
authors.forename: M A
authors.initials: MA
authors.lastname: Wells
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003062:Codon; D018076:DNA, Complementary / Q000235:genetics / Q000302:isolation & purification*; D003576:Electron Transport Complex IV / Q000235:genetics*; D005815:Genetic Code; D007448:Invertebrates / Q000235:genetics*; D008928:Mitochondria / Q000201:enzymology*; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000235:genetics*; D013045:Species Specificity
chemical_list: D003062:Codon; D018076:DNA, Complementary; D010446:Peptide Fragments; D003576:Electron Transport Complex IV