title: The intron-exon structure of the porcine E-selectin-encoding gene.
abstract: We have cloned and sequenced the gene encoding porcine E-selectin. The gene comprises 12 exons and 11 introns. Two pseudoexons are contained within intron 4 and intron 6. These sequences are similar to the corresponding exons in the human E-selectin sequence; however, they are not present in the porcine E-selectin-encoding cDNA. Transcription starts at position -498 relative to the translation initiation site. The first ATG is located within exon 2. Translation stops in exon 11 leaving exon 12 untranslated in its entirety.
authors.affiliation: Sandoz Center for Immunobiology, New England Deaconess Hospital, Harvard Medical School, Boston, MA 02215, USA. hwinkler@nedhmail.nedh.harvard.edu
authors.forename: H
authors.initials: H
authors.lastname: Winkler
authors.forename: C
authors.initials: C
authors.lastname: Brostjan
authors.forename: V
authors.initials: V
authors.lastname: Csizmadia
authors.forename: G
authors.initials: G
authors.lastname: Natarajan
authors.forename: J
authors.initials: J
authors.lastname: Anrather
authors.forename: F H
authors.initials: FH
authors.lastname: Bach
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D018076:DNA, Complementary; D019040:E-Selectin / Q000235:genetics*; D005091:Exons; D006801:Humans; D007438:Introns; D008969:Molecular Sequence Data; D013552:Swine
chemical_list: D018076:DNA, Complementary; D019040:E-Selectin