title: Oesophageal motility disorders in patients with psychiatric disease.
abstract: Clinical and experimental observations indicate that the motility of the oesophagus may be affected by emotional stimuli. The aim of this study was to evaluate the incidence of oesophageal contractility impairment in patients suffering from a psychiatric disorder. Fifty-one patients admitted to the psychiatric department were submitted to an oesophageal transit study by means of krypton-81m. All patients with an abnormal oesophageal transit underwent manometry and endoscopy. The level of depression and anxiety was evaluated by the treating psychiatrist, using the Hamilton Depression and Anxiety Rating Scales. The oesophageal transit was abnormal in 13 patients. Two of these 13 patients refused manometric investigation. In ten of the 11 remaining patients, the manometry revealed functional motor abnormalities. Endoscopy, performed in all these ten patients, was normal. In conclusion, a high percentage of oesophageal contractility disturbances was found in psychiatric patients complaining of anxiety and/or depression. These abnormalities were detected by scintigraphy as well as by manometry. Owing to the normal endoscopic findings, these contraction abnormalities are likely to reflect a functional motor impairment.
authors.affiliation: Department of Nuclear Medicine, Free University of Brussels, Brussels, Belgium.
authors.forename: J
authors.initials: J
authors.lastname: Roland
authors.forename: H
authors.initials: H
authors.lastname: Dhaenen
authors.forename: H R
authors.initials: HR
authors.lastname: Ham
authors.forename: O
authors.initials: O
authors.lastname: Peters
authors.forename: A
authors.initials: A
authors.lastname: Piepsz
mesh_terms: D001007:Anxiety / Q000503:physiopathology; D003863:Depression / Q000503:physiopathology; D015154:Esophageal Motility Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology*; D004945:Esophagoscopy; D004947:Esophagus / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D006801:Humans; D015994:Incidence; D007727:Krypton Radioisotopes; D008297:Male; D008365:Manometry; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000150:complications* / Q000503:physiopathology; D011877:Radionuclide Imaging
chemical_list: D007727:Krypton Radioisotopes