[Secondary osteosarcoma in Paget disease].
The incidence of Paget's disease in Germany is about 3%. Up to 10% of all affected individuals develop secondary osteosarcomas in the affected bone areas. Compared to primary osteosarcoma patients with Paget's sarcoma differ in regard to age, tumor localisation, therapy, prognosis and radiological symptoms. The following case report describes clinical features, therapy and the typical radiological findings.
Dieckmann
C
C
Abteilung Röntgendiagnostik, Universitätskrankenhaus Hamburg-Eppendorf.
Bruns
J
J
Maas
R
R
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001706:Biopsy; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D006801:Humans; D006811:Humerus / Q000473:pathology / Q000601:surgery; D008159:Lumbar Vertebrae / Q000473:pathology / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D010001:Osteitis Deformans / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D012516:Osteosarcoma / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D012785:Shoulder Joint / Q000473:pathology / Q000601:surgery; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed