title: Cell-cell signalling: Wingless lands at last.
abstract: A novel class of receptor-the Frizzled family-has been identified and the members shown to be receptors for Wingless and its homologs, the Wnts, which mediate key cell-cell interactions during the development of fruitflies and vertebrates, respectively.
authors.affiliation: Max-Planck Institüt für Immunbiologie, Freiberg, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Orsulic
authors.forename: M
authors.initials: M
authors.lastname: Peifer
mesh_terms: D000818:Animals; D002450:Cell Communication; D004330:Drosophila / Q000378:metabolism*; D029721:Drosophila Proteins; D051157:Frizzled Receptors; D053823:Hedgehog Proteins; D006801:Humans; D019476:Insect Proteins / Q000378:metabolism; D011518:Proto-Oncogene Proteins / Q000378:metabolism*; D011956:Receptors, Cell Surface / Q000378:metabolism*; D043562:Receptors, G-Protein-Coupled; D017981:Receptors, Neurotransmitter; D015398:Signal Transduction / Q000502:physiology*; D051155:Wnt1 Protein
chemical_list: D029721:Drosophila Proteins; D051157:Frizzled Receptors; D053823:Hedgehog Proteins; D019476:Insect Proteins; D011518:Proto-Oncogene Proteins; D011956:Receptors, Cell Surface; D043562:Receptors, G-Protein-Coupled; D017981:Receptors, Neurotransmitter; D051155:Wnt1 Protein; C101703:fz2 protein, Drosophila; C074622:wg protein, Drosophila; C077245:hh protein, Drosophila