title: [Spinal tuberculous arachnoiditis].
abstract: Tuberculous arachnoiditis of the spine is a rare complication of tuberculous meningitis and can occur despite correct treatment. We report two cases of arachnoiditis in patients with tuberculous meningitis. In both cases, clinical signs included flaccid paraparesia and sphincter dystonia. Evidence for diagnosis was obtained with magnetic resonance imaging of the lombosacral spine after a 3 or 11 week course. Adding corticosteroids to the anti-tuberculosis therapy provided spectacular clinical improvement within 8 days in both cases. The diagnosis of tuberculous arachnoiditis of the spine is often made late but can be confirmed easily with magnetic resonance imaging. Our cases emphasize the importance of oral corticosteroid therapy to avoid severe sequellae.
authors.affiliation: Clinique des Maladies infectieuses et tropicales, Hôpital Saint-Louis, Paris.
authors.forename: A
authors.initials: A
authors.lastname: de La Blanchardière
authors.forename: J B
authors.initials: JB
authors.lastname: Stern
authors.forename: J M
authors.initials: JM
authors.lastname: Molina
authors.forename: P
authors.initials: P
authors.lastname: Lesprit
authors.forename: J
authors.initials: J
authors.lastname: Gasnault
authors.forename: E
authors.initials: E
authors.lastname: de Kerviler
authors.forename: J M
authors.initials: JM
authors.lastname: Decazes
authors.forename: J
authors.initials: J
authors.lastname: Modai
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D001100:Arachnoiditis / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D014390:Tuberculosis, Meningeal / Q000150:complications*; D014399:Tuberculosis, Spinal / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology
chemical_list: D000995:Antitubercular Agents; D005938:Glucocorticoids; D011241:Prednisone