[Features of the antiviral effect of carbocyclic compounds depending on their concentration].
Antiviral agents and new agents possessing antiviral properties and characterized by a carbocyclic (carcass) structure were shown to differ from other, specifically, heterocyclic compounds, by the presence of a range from the maximally effective to maximally tolerable concentrations, the antiviral effect decreasing in this range of concentrations. This feature was observed in cell cultures, chick embryos, and laboratory animals in experiments with different influenza viruses and RS virus.
Boreko
E I
EI
Pavlova
N I
NI
Votiakov
V I
VI
D000818:Animals; D000998:Antiviral Agents / Q000737:chemistry / Q000494:pharmacology*; D002642:Chick Embryo; D004305:Dose-Response Relationship, Drug; D009980:Influenza A virus / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D012136:Respiratory Syncytial Viruses / Q000187:drug effects*
D000998:Antiviral Agents