title: Long-term bone marrow cultures in polycythaemia vera and essential thrombocythaemia.
abstract: Bone marrow samples of 8 patients with essential thrombocythaemia and three patients with polycythaemia vera were cultured in long-term bone marrow cultures. The production of non-adherent cells and colony-forming unit-granulocyte-macrophage harvested weekly did not differ from that of 29 healthy bone marrow transplant donors. There was a trend towards less complete stromal confluence in patients with a myeloproliferative disease.
authors.affiliation: Department of Medicine, Helsinki University Central Hospital, Finland.
authors.forename: R
authors.initials: R
authors.lastname: Jantunen
authors.forename: E
authors.initials: E
authors.lastname: Juvonen
authors.forename: A
authors.initials: A
authors.lastname: Aimolahti
authors.forename: T
authors.initials: T
authors.lastname: Ruutu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001853:Bone Marrow / Q000378:metabolism*; D002478:Cells, Cultured; D005260:Female; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000302:isolation & purification; D006412:Hematopoietic Stem Cells / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011087:Polycythemia Vera / Q000378:metabolism*; D013922:Thrombocytosis / Q000378:metabolism*
chemical_list: D016178:Granulocyte-Macrophage Colony-Stimulating Factor