[The predictive value of cyclic nucleotide ratio in the prognosis of experimental tumors].
The report deals with the predictive value of a procedure for lifetime detection of tumor in experimental animals. The database included the results of regular cAMP/cHMP tests carried out in 54 rats with radionuclide-inducted tumors and 24 tumor-free rats. The data were processes by statistical methods and the informative value was determined on the basis of standard recommendations. The test was shown to have high sensitivity (85.2%), sufficient predictive value (73%) and diagnostic effectiveness (68%). Application of the test in groups of humans at high risk of tumor development is discussed.
Rabinovich
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Sokolova
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D000818:Animals; D000242:Cyclic AMP / Q000032:analysis; D006152:Cyclic GMP / Q000032:analysis; D009374:Neoplasms, Experimental / Q000209:etiology / Q000235:genetics*; D009712:Nucleotides, Cyclic / Q000032:analysis*; D011237:Predictive Value of Tests; D011379:Prognosis; D051381:Rats; D012680:Sensitivity and Specificity
D009712:Nucleotides, Cyclic; D000242:Cyclic AMP; D006152:Cyclic GMP