title: Toxocariasis as a cause of renal disease in children in Sharkia Governorate, Egypt.
abstract: Eighty four children (40 males and 44 female) suffering from renal troubles were chosen as well as 20 healthy children as a control group. Urine and stool of patients were examined and chosen to be free from parasitic infections other than Toxocara. Each child was subjected to history taking, full clinical examination, urine analysis, kidney function tests and differential leucocytic count, examination of sera and urine by ELISA and microprecipitin tests for Toxocara antibodies. ELISA revealed 10.7% of patients to be seropositive for toxocariasis versus 5.3% in control group. This difference was statistically insignificant P > 0.05. In urine, ELISA revealed 2 positive cases out of the 84 patients, while it was negative in control group. These 2 cases were suffering from nephrotic syndrome. Microprecipitin test in sera was positive in 9.5% of patients and negative in control group. It was also negative in urine of patients and control group. Eosinophilia was found in 66.6% of seropositive patients. IgG antibodies to Toxocara were detected in males more than females between the age of 2-7 years, but insignificant (P > 0.05). It was also found in 77.7% of rural compared to 22.2% of urban areas. This difference was statistically significant (P < 0.05). It was concluded that toxocariasis should not be missed in the differential diagnosis of such renal diseases especially those who are not responds to the traditional management.
authors.affiliation: Department of Parasitology, Faculty of Medicine, Zagazig University, Egypt.
authors.forename: S M
authors.initials: SM
authors.lastname: Nada
authors.forename: B E
authors.initials: BE
authors.lastname: Abazza
authors.forename: L A
authors.initials: LA
authors.lastname: Mahmoud
authors.forename: Y S
authors.initials: YS
authors.lastname: Habeeb
authors.forename: H F
authors.initials: HF
authors.lastname: Hussein
authors.forename: O T
authors.initials: OT
authors.lastname: Amer
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004534:Egypt; D005260:Female; D005921:Glomerulonephritis / Q000209:etiology*; D006801:Humans; D007223:Infant; D008297:Male; D009404:Nephrotic Syndrome / Q000209:etiology*; D012424:Rural Population; D014120:Toxocariasis / Q000150:complications*; D014505:Urban Population