title: Comparison of sufentanil/propofol versus isoflurane/nitrous oxide anaesthesia on mesenteric artery blood flow.
abstract: Duplex sonography was used to determine the changes in mesenteric arterial blood flow occurring in patients undergoing aortic surgery, anaesthetised either by total intravenous anaesthesia with propofol and sufentanil (group A) or inhalational anaesthesia with isoflurane and nitrous oxide (group B). Sixteen patients were studied. Measurements were performed immediately before and 15 min after induction of anaesthesia, before surgery. There was a 38% decrease (p = 0.015) in the superior mesenteric artery end diastolic velocity in group A and a 23% decrease (p = 0.033) in the superior mesenteric artery peak systolic velocity in group B. There were no changes in any of the other sonography parameters in either group. We conclude that neither total intravenous anaesthesia with propofol and sufentanil nor inhalational anaesthesia with isoflurane and nitrous oxide have any clinically significant influence on mesenteric blood flow in the absence of surgical stimulation.
authors.affiliation: Department of Anaesthesiology, University Hospital Leiden, The Netherlands.
authors.forename: J H
authors.initials: JH
authors.lastname: Zwijsen
authors.forename: J G
authors.initials: JG
authors.lastname: Bovill
authors.forename: R H
authors.initials: RH
authors.lastname: Geelkerken
authors.forename: T A
authors.initials: TA
authors.lastname: Delahunt
authors.forename: J H
authors.initials: JH
authors.lastname: van Bockel
authors.forename: J
authors.initials: J
authors.lastname: Hermans
mesh_terms: D000368:Aged; D000769:Anesthesia, Inhalation; D000771:Anesthesia, Intravenous; D001012:Aorta, Abdominal / Q000601:surgery; D003864:Depression, Chemical; D005260:Female; D006801:Humans; D007530:Isoflurane; D008297:Male; D008638:Mesenteric Arteries / Q000000981:diagnostic imaging; D008875:Middle Aged; D009609:Nitrous Oxide; D015742:Propofol; D012039:Regional Blood Flow / Q000187:drug effects; D017409:Sufentanil; D018616:Ultrasonography, Doppler, Duplex
chemical_list: D017409:Sufentanil; D007530:Isoflurane; D009609:Nitrous Oxide; D015742:Propofol