title: Orbital and eyelid manifestations of neurofibromatosis: a clinical study and literature review.
abstract: Neurofibromatosis (NF) is an autosomal dominant abnormality that may effect multiple organ systems. Eyelids, orbits, and adjacent tissues may be involved with varying frequency and severity. Plexiform neurofibromas, causing mechanical ptosis and proptosis, optic nerve gliomas, and sphenoid wing dysplasia are some of the more common orbital and eyelid findings in NF. A series of 10 patients followed for up to 18 years is reported to describe features associated with NF, their clinical evolution, and their management.
authors.affiliation: Department of Ophthalmology, Fitzsimons Army Medical Center, Aurora, Colorado 80045, USA.
authors.forename: S R
authors.initials: SR
authors.lastname: Farris
authors.forename: A S
authors.initials: AS
authors.lastname: Grove
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005141:Eyelid Diseases / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009456:Neurofibromatosis 1 / Q000150:complications*; D009916:Orbital Diseases / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D014057:Tomography, X-Ray Computed