title: Laparoscopic-modified Nissen fundoplication in children with familial dysautonomia.
abstract: Children with familial dysautonomia (FD) often require an antireflux operation and gastrostomy to prevent the detrimental effects of aspirated gastric juice on the lungs and to facilitate liquid feeding. The aim of this study was to examine whether a laparoscopic procedure in such patients is as safe and effective as the traditional open technique. The data for all pediatric patients who underwent a laparoscopic antireflux procedure for familial dysautonomia were reviewed and compared with those the last pediatric patients with FD who were operated upon using the open technique, before the introduction of the laparoscopic procedure. Of the 61 children who underwent an antireflux procedure for FD (1978-1996), 13 were operated on laparoscopically. The authors found that the postoperative course of these patients was less complicated than that of patients who had the traditional laparotomy procedure. There was no need for mechanical ventilation during the postoperative course, and there were no respiratory complications. The mean hospitalization period was significantly shorter (7.9 days v 13.2 days). There were no complications attributable to laparoscopy, and the antireflux procedure has been effective in all patients (short-term follow-up). The authors conclude that laparoscopic procedures that include a modified Nissen fundoplication, gastrostomy, and appendectomy are feasible and as safe as conventional surgery for the treatment of FD in children. It appears that this approach has fewer complications than laparotomy, might reduce the need for postoperative mechanical ventilation, and is associated with a shorter postoperative stay.
authors.affiliation: Department of General and Pediatric Surgery, Hadassah University Hospital Mount Scopus, Jerusalem, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Szold
authors.forename: R
authors.initials: R
authors.lastname: Udassin
authors.forename: C
authors.initials: C
authors.lastname: Maayan
authors.forename: A
authors.initials: A
authors.lastname: Vromen
authors.forename: D
authors.initials: D
authors.lastname: Seror
authors.forename: O
authors.initials: O
authors.lastname: Zamir
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004402:Dysautonomia, Familial / Q000150:complications / Q000601:surgery*; D018662:Fundoplication / Q000379:methods*; D005746:Gastric Emptying; D005764:Gastroesophageal Reflux / Q000209:etiology / Q000601:surgery*; D005774:Gastrostomy; D006801:Humans; D007223:Infant; D010535:Laparoscopy / Q000379:methods*; D007902:Length of Stay; D010149:Postoperative Pain; D011183:Postoperative Complications; D016896:Treatment Outcome