Langerhans' cell histiocytosis: report of three cases with unusual oral soft tissue involvement.
Three cases of Langerhans' cell histiocytosis (histiocytosis X) are reported in which the clinical presentations were (1) soft-tissue enlargements, (2) oral ulcerations, and (3) leukoplakia. Each case was without bone involvement at the time of diagnosis, and two patients were older than 60 years of age. Definitive diagnoses were aided with the use of immunohistochemistry.
Cleveland
D B
DB
Department of Pathology and Laboratory Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA.
Goldberg
K M
KM
Greenspan
J S
JS
Seitz
T E
TE
Miller
A S
AS
D000328:Adult; D005882:Gingival Diseases / Q000209:etiology* / Q000473:pathology; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications* / Q000473:pathology; D006801:Humans; D007972:Leukoplakia, Oral / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D019226:Oral Ulcer / Q000209:etiology* / Q000473:pathology