title: Postnatal changes in the reticular lamina of the guinea pig organ of Corti.
abstract: The dimensions of the apical surfaces of hair cells were measured in guinea pigs, aged from 3 weeks before term to 25 weeks after birth. In the basal two-thirds of the cochlea, the apical surfaces of the outer hair cells and their supporting cells changed with age, shrinking in a direction radial across the cochlear duct. There was an associated widening of the angle of the 'V' of the rows of stereocilia. Further apically, between 12 and 16 mm from the base of the cochlea, the outer hair cells and their supporting cells underwent the opposite change, becoming wider in a radial direction with age. The changes were seen before birth and continued for more than 3 weeks after birth. The results suggest that the guinea pig cochlea continues certain developmental processes for a considerable time after birth.
authors.affiliation: Department of Physiology and Pharmacology, University of Queensland, Australia. s.zhou@vthrc.uq.edu.au
authors.forename: S
authors.initials: S
authors.lastname: Zhou
authors.forename: J O
authors.initials: JO
authors.lastname: Pickles
mesh_terms: D000375:Aging; D000818:Animals; D000831:Animals, Newborn; D006168:Guinea Pigs; D018072:Hair Cells, Auditory, Outer / Q000166:cytology* / Q000648:ultrastructure; D007760:Labyrinth Supporting Cells / Q000166:cytology / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D009925:Organ of Corti / Q000166:cytology* / Q000648:ultrastructure; D016707:Tissue Fixation