title: Absence of neglect for mental representations during the intracarotid amobarbital procedure.
abstract: BACKGROUND
  The unilateral suppression of right-hemisphere electrophysiological activity during the intracarotid amobarbital procedure results in left neglect on visuomotor search tasks.
  
  
  OBJECTIVE
  To investigate whether right-hemisphere inactivation during the intracarotid amobarbital procedure also results in left neglect of the mental representation of a remembered scene.
  
  
  METHODS
  Before the intracarotid amobarbital procedure, 16 subjects were asked to draw a room from their homes. Following the right-hemisphere injection, subjects wee tested for the presence of left neglect of extrapersonal space using a Random Letter Cancellation Test. To test for neglect of the mental representation of a remembered scene, they were then asked to report items from the room they had drawn.
  
  
  RESULTS
  While 10 of the 16 subjects showed left neglect on the Random Letter Cancellation Test, only one subject showed left neglect of the mental representation. The other 15 subjects recalled approximately equal numbers of items from the left and the right hemispaces.
  
  
  CONCLUSIONS
  These results replicate previous findings of left neglect of extra personal space during the intracarotid amobarbital procedure and fail to show concurrent neglect for mental representations. They provide further evidence for the multiplicity and dissociability of the behavioral manifestations of neglect.
authors.affiliation: Behavioral Neurology Unit, Beth Israel Hospital and Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: D S
authors.initials: DS
authors.lastname: Manoach
authors.forename: M
authors.initials: M
authors.lastname: O'Connor
authors.forename: S
authors.initials: S
authors.lastname: Weintraub
mesh_terms: D000654:Amobarbital / Q000008:administration & dosage / Q000494:pharmacology; D001288:Attention / Q000187:drug effects*; D001921:Brain / Q000187:drug effects; D005260:Female; D007839:Functional Laterality; D018757:GABA Modulators / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D007269:Injections, Intra-Arterial; D008297:Male; D008568:Memory / Q000187:drug effects*
chemical_list: D018757:GABA Modulators; D000654:Amobarbital