A novel inhibitor of platelet aggregation from the Cyanophyceae Oscillatoria rosea (NIES-208)
(2S)-1-O-Palmitoleyl-3-O-beta-D-galactopyranosylglycerol was isolated from the marine alga Oscillatoria rosea. It caused a concentration-dependent inhibition of platelet aggregation induced by U46619. Its structure was elucidated by spectroscopic analysis and chemical evidence.
Rho
M C
MC
Matsunaga
K
K
Yasuda
K
K
Ohizumi
Y
Y
D019796:15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; D001792:Blood Platelets / Q000187:drug effects / Q000502:physiology; D000458:Cyanobacteria; D005697:Galactosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000302:isolation & purification* / Q000494:pharmacology; D011450:Prostaglandin Endoperoxides, Synthetic / Q000494:pharmacology; D013928:Thromboxane A2 / Q000031:analogs & derivatives / Q000494:pharmacology; D014662:Vasoconstrictor Agents / Q000494:pharmacology
C102720:1-O-palmitoyl-3-galactopyranosylglycerol; D005697:Galactosides; D010975:Platelet Aggregation Inhibitors; D011450:Prostaglandin Endoperoxides, Synthetic; D014662:Vasoconstrictor Agents; D013928:Thromboxane A2; D019796:15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid