[Thalamocortical relations in the brain of white rats in the postischemic period (a morphometric study of the cyto- and synaptoarchitectonics)].
Numerical density of neurons and synapses in one mm3 was determined in layer III and IV of sensomotor cortex (SMC) and ventrobasal complex of thalamic nuclei (VBN) in the dynamics of postischemic period. It was demonstrated that during first seven days numerical density of neurons and synapses changes equally. Fourteen and especially thirty days later VBN of thalamus and synaptic population of layers III and IV of SMC, forming the SMC "entry" were most disturbed. A conclusion is made on more fast synapse restoration in dendritic zone of VBN neurons and insufficiency of this period (thirty days) for the forming of new contacts between the axons of the reserved VBN neurons and the reserved cortical neurons which can probably be a structural base of postischemic dysfunctions in the specific thalamo-cortical system.
Stepanov
S S
SS
Semchenko
V V
VV
D000818:Animals; D002545:Brain Ischemia / Q000473:pathology*; D002452:Cell Count; D003584:Cytological Techniques; D007395:Interneurons / Q000473:pathology*; D008297:Male; D008854:Microscopy, Electron; D009044:Motor Cortex / Q000473:pathology*; D009474:Neurons / Q000473:pathology*; D051381:Rats; D013569:Synapses / Q000473:pathology*; D013787:Thalamic Nuclei / Q000473:pathology*; D013997:Time Factors