title: Anaplastic (malignant) ganglioglioma arising from heterotopic grey matter nodules.
abstract: Anaplastic ganglioglioma is a rare malignant neoplasm. The short clinical course and the anaplastic histological features are characteristics of malignant ganglioglioma. Immunohistochemistry is necessary for the final diagnosis. The MRI appearances are described here for the first time in literature. Nodular grey matter heterotopias had been demonstrated and the patient developed an anaplastic ganglioglioma two years later, on the same place where the grey matter heteropias had been seen. This finding supports the hypothesis that these tumours may arise from grey matter nodules.
authors.affiliation: Department of Radiology, University Hospitals K.U.L. Leuven, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Demaerel
authors.forename: M
authors.initials: M
authors.lastname: Droessaert
authors.forename: M
authors.initials: M
authors.lastname: Lammens
authors.forename: J
authors.initials: J
authors.lastname: Menten
authors.forename: B
authors.initials: B
authors.lastname: Nuttin
authors.forename: R
authors.initials: R
authors.lastname: Verbeeck
authors.forename: G
authors.initials: G
authors.lastname: Wilms
authors.forename: A L
authors.initials: AL
authors.lastname: Baert
mesh_terms: D000328:Adult; D001706:Biopsy; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D002828:Choristoma / Q000000981:diagnostic imaging* / Q000473:pathology; D004805:Ependyma; D005260:Female; D018303:Ganglioglioma / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D014057:Tomography, X-Ray Computed