Clinical application of nonselective assisted hatching of human embryos.
OBJECTIVE
To evaluate the effect of nonselective assisted hatching on pregnancy rate (PR) and to provide an alternative and simplified method for clinical application of assisted hatching.


METHODS
Retrospective analysis of clinical data.


METHODS
Private infertility practice.


METHODS
Women from 258 consecutive stimulated IVF cycles.


METHODS
Assisted hatching was performed on each transferred embryo regardless of patient history, embryo morphology, or other selection criteria routinely applied to many IVF programs.


METHODS
Pregnancy, live birth, and implantation rates.


RESULTS
Of 258 consecutive patients who had nonselective assisted hatching, 109 (42%) had clinical pregnancies, with 93 (36%) live births and 178 (20%) embryos implanted.


CONCLUSIONS
Nonselective assisted hatching resulted in an acceptable PR and provided an alternative and simplified method for clinical application of assisted hatching.
Hu
Y
Y
Northwest Center for Infertility and Reproductive Endocrinology, Margate, Florida 33063, USA.
Hoffman
D I
DI
Maxson
W S
WS
Ory
S J
SJ
D000328:Adult; D001723:Birth Rate; D010064:Embryo Implantation; D004622:Embryo, Mammalian; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008846:Micromanipulation; D011247:Pregnancy; D018873:Pregnancy Rate; D012099:Reproductive Techniques; D012189:Retrospective Studies