title: Wilms' tumour : a clinicopathologic study with special reference to its morphologic variants.
abstract: Twenty five cases of Wilms' tumour were studied with special reference to their morphological variations. Wilms' tumour constituted 7.6% of all the malignant tumours of childhood and 50% of renal malignancies. Male/female ratio was 4:1; the mean age being 3.5 years. Left side was commonly involved (60.9%) center dot bilateral involvement in one case (4.3%). Morphologic study revealed triphasic pattern in 60% cases, biphasic (epithelial + stromal) in 12% and monophasic pattern in 28%. Other features observed were myxomatous degeneration, rhabdomyoblasts, calcification and squamous epithelial pearls seen in 20%, 12%, 8% and 4% respectively.
authors.affiliation: Department of Pathology and Surgery, King George's Medical College, Lucknow, India.
authors.forename: S
authors.initials: S
authors.lastname: Sharma
authors.forename: P
authors.initials: P
authors.lastname: Nath
authors.forename: A N
authors.initials: AN
authors.lastname: Srivastava
authors.forename: K M
authors.initials: KM
authors.lastname: Singh
mesh_terms: D000293:Adolescent; D002454:Cell Differentiation; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000473:pathology*; D008297:Male; D017678:Sex Distribution; D009396:Wilms Tumor / Q000473:pathology*