[Effect of heparin-supplemented iopamidol on the blood coagulation].
The purpose of the study was to determine the concentration of heparin to be added to iopamidol in order to assure adequate anticoagulant activity and tolerability. Iopamidol that contained heparin at a concentration of 3 U/ml showed the anticoagulant activity similar to ionic contrast agents, while maintaining excellent tolerability.
Kawai
J
J
Research Department, Nihon Schering K.K.
Miyazawa
T
T
D000818:Animals; D000925:Anticoagulants / Q000008:administration & dosage*; D001777:Blood Coagulation / Q000187:drug effects*; D003287:Contrast Media / Q000008:administration & dosage / Q000494:pharmacology*; D006493:Heparin / Q000008:administration & dosage*; D007479:Iopamidol / Q000008:administration & dosage / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR
D000925:Anticoagulants; D003287:Contrast Media; D006493:Heparin; D007479:Iopamidol