title: Immunity to hepatitis A in paediatric and nursery nurses.
abstract: A cross-sectional epidemiological survey of immunity to the hepatitis A virus (HAV) was undertaken in paediatric and nursery nurses to ascertain whether these occupational groups were at an increased risk of infection with the virus. Seropositivity to HAV was measured in 33 surgical (control), 36 paediatric, 55 nursery and 29 specialist paediatric nurses in a district general hospital, community clinics and a children's hospital in the West Midlands. IgG antibodies to HAV were found in 27% of surgical (control), 31% of paediatric (relative risk [RR] = 1.19, 95% confidence interval [Cl] = 0.56-2.51), 26% of nursery nurses (RR = 0.99, Cl = 0.48-2.04) and 10% of specialist paediatric nurses (RR = 0.40, Cl = 0.12-1.35). These data are comparable to immunity to HAV for this age group in the general population of this country and do not support routine immunization of paediatric or nursery nurses against HAV.
authors.affiliation: Occupational Health Service, Dudley Priority Health NHS Trust, West Midlands, UK.
authors.forename: C J
authors.initials: CJ
authors.lastname: Poole
authors.forename: A T
authors.initials: AT
authors.lastname: Shakespeare
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D003625:Data Collection; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006506:Hepatitis A / Q000453:epidemiology / Q000635:transmission*; D017957:Hepatitis A Virus, Human / Q000276:immunology*; D006508:Hepatitis Antibodies / Q000032:analysis*; D006801:Humans; D007223:Infant; D017758:Infectious Disease Transmission, Patient-to-Professional; D008875:Middle Aged; D009725:Nurseries, Hospital; D009726:Nurses; D010372:Pediatrics; D015995:Prevalence; D012016:Reference Values
chemical_list: D006508:Hepatitis Antibodies