Recurrent histiocytic necrotizing lymphadenitis (Kikuchi's disease) in an human T lymphotropic virus type I carrier.
We describe a case of recurrent histiocytic necrotizing lymphadenitis (HNL) with aseptic meningitis. The patient was a 46-year-old male and a carrier of human T lymphotropic virus type I (HTLV-I). The patient had a past medical history of at least three relapses of HNL. In addition, his sister, who was also an HTLV-I carrier, had recurrent clinical episodes consistent with those of HNL, suggesting familial HNL occurrence. This observation suggests the possibility that HTLV-I infection is relevant to the pathogenesis of HNL.
Atarashi
K
K
Department of Internal Medicine, Hiratsuka Kyosai Hospital.
Yoshimura
N
N
Nodera
H
H
Tsukimoto
K
K
Beppu
H
H
Kanayama
M
M
D000914:Antibodies, Viral / Q000032:analysis; D016827:CD8 Antigens / Q000276:immunology; D002353:Carrier State / Q000821:virology*; D002455:Cell Division; D017809:Fatal Outcome; D015490:HTLV-I Infections / Q000150:complications*; D006566:Herpesviridae Infections / Q000150:complications; D015654:Herpesvirus 6, Human / Q000276:immunology; D006644:Histiocytes / Q000276:immunology / Q000473:pathology*; D015368:Human T-lymphotropic virus 1; D006801:Humans; D007150:Immunohistochemistry; D016256:Lewis X Antigen / Q000276:immunology; D008199:Lymphadenitis / Q000209:etiology* / Q000235:genetics / Q000473:pathology; D008297:Male; D008582:Meningitis, Aseptic / Q000150:complications; D008875:Middle Aged; D009336:Necrosis; D010375:Pedigree; D012008:Recurrence
D000914:Antibodies, Viral; D016827:CD8 Antigens; D016256:Lewis X Antigen