title: [Sleep disorders and neuroendocrine regulation in depression].
abstract: In a series of investigations we explored 24 hour neuroendocrine profiles as well as sleep patterns in a sample of monozygotic and dizygotic normal twins as well as in a group of depressed and schizophrenic patients. Our results indicate that genetic factors influence some sleep variables, mainly the slow wave sleep. They also indicate that a disorder of circadian time-keeping (a phase advance of the biological clock) characterizes some forms of affective illness.
authors.affiliation: Service de Psychiatrie, Hopital Erasme, Bruxelles, Belgique.
authors.forename: P
authors.initials: P
authors.lastname: Linkowski
authors.forename: P P
authors.initials: PP
authors.lastname: Hubain
mesh_terms: D000328:Adult; D001143:Arousal / Q000235:genetics / Q000502:physiology; D002940:Circadian Rhythm / Q000502:physiology; D003866:Depressive Disorder / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology* / Q000523:psychology; D004200:Diseases in Twins / Q000235:genetics / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D009490:Neurosecretory Systems / Q000503:physiopathology*; D012559:Schizophrenia / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology; D012565:Schizophrenic Psychology; D012893:Sleep Wake Disorders / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology* / Q000523:psychology