title: Changes in lung volume and volume of emphysema after unilateral lung reduction surgery: analysis with CT lung densitometry.
abstract: OBJECTIVE
  To evaluate changes in volume of the lungs and volume of emphysema after unilateral lung reduction surgery (ULRS) by using computed tomographic (CT) lung densitometry.
  
  
  METHODS
  Twenty-eight patients underwent CT before and 3 months after ULRS. With use of a density mask software program and a three-dimensional graphics workstation, CT scans were analyzed to define the volume of the lungs and the volume of emphysema. Pre- and postoperative mean CT numbers were determined.
  
  
  RESULTS
  After ULRS, the surgically reduced lung volume decreased 22%, and the intact opposite lung volume increased 4%. Emphysema in the surgically reduced lung decreased 14% and was unchanged in the intact opposite lung. Mean CT numbers in the surgically reduced lung increased 26 HU but were unchanged in the intact opposite lung.
  
  
  CONCLUSIONS
  The effects of ULRS on each lung can be evaluated by using CT lung densitometry and a three-dimensional graphics workstation. ULRS reduces emphysema and lung volume in the surgically reduced lung without statistically significant worsening of contralateral emphysema at 3 months.
authors.affiliation: Department of Radiology, University of Pittsburgh Medical Center, Montefiore Hospital, PA 15213-2582, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Holbert
authors.forename: M L
authors.initials: ML
authors.lastname: Brown
authors.forename: F C
authors.initials: FC
authors.lastname: Sciurba
authors.forename: R J
authors.initials: RJ
authors.lastname: Keenan
authors.forename: R J
authors.initials: RJ
authors.lastname: Landreneau
authors.forename: A D
authors.initials: AD
authors.lastname: Holzer
mesh_terms: D000328:Adult; D000368:Aged; D003936:Diagnosis, Computer-Assisted; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery*; D008176:Lung Volume Measurements / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011656:Pulmonary Emphysema / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000601:surgery*; D012129:Respiratory Function Tests; D014057:Tomography, X-Ray Computed