title: Antibodies against toxoplasma in children and adults with malignancy.
abstract: Twenty five children and adults with different types of malignancies were picked up from the attendants of Mansoura University Hospital and Ain Shams University Paediatrics Hospital. Their sera were examined for anti-Toxoplasma IgG and IgM antibodies by the micro-ELISA before and after chemotherapy treatment. Ten normal cross-matched individuals were selected as a control group. The results revealed seropositive IgG in 22 (88%) of patients before treatment and in 23 (92%) after treatment. The anti-Toxoplasma IgM was positive in three (12%) patients before treatment and in six (24%) after treatment. On the other hand, two of the control group showed a seropositive Toxoplasma IgG (20%) but negative anti-Toxoplasma IgM. The results were discussed.
authors.affiliation: Department of Parasitology, Faculty of Medicine, Mansoura University, Egypt.
authors.forename: A M
authors.initials: AM
authors.lastname: el Shazly
authors.forename: E M
authors.initials: EM
authors.lastname: Afify
authors.forename: T A
authors.initials: TA
authors.lastname: Morsy
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D002648:Child; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications* / Q000188:drug therapy; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000150:complications* / Q000276:immunology
chemical_list: D000913:Antibodies, Protozoan; D000970:Antineoplastic Agents; D007074:Immunoglobulin G; D007075:Immunoglobulin M