title: Foreign body reactions to monofilament and braided polypropylene mesh used as preperitoneal implants in pigs.
abstract: OBJECTIVE
  To compare the foreign body reaction of the monofilament polypropylene (Prolene) mesh, and the multifilament Surgipro mesh. Both types of mesh are widely used in laparoscopic inguinal hernia repair.
  
  
  METHODS
  Prospective experimental study.
  
  
  METHODS
  University hospital, The Netherlands.
  
  
  METHODS
  Six female Yorkshire & Dutch landway pigs.
  
  
  METHODS
  Laparoscopic transabdominal implantation of six Surgipro meshes and six Prolene meshes in 12 inguinal sites.
  
  
  METHODS
  At 3, 6, and 12 weeks after implantation the foreign body reaction was measured by counting multinucleated giant cells at the mesh-tissue interface.
  
  
  RESULTS
  At all times the numbers of multinucleated giant cells at the mesh tissue interface were significantly larger with Surgipro than with Prolene (p < 0.001).
  
  
  CONCLUSIONS
  There is significantly more foreign body reaction after implantation of Surgipro than Prolene mesh.
authors.affiliation: Department of Surgery, University Hospital Maastricht, The Netherlands.
authors.forename: G L
authors.initials: GL
authors.lastname: Beets
authors.forename: P M
authors.initials: PM
authors.lastname: Go
authors.forename: H
authors.initials: H
authors.lastname: van Mameren
mesh_terms: D000818:Animals; D005260:Female; D005549:Foreign-Body Reaction / Q000473:pathology*; D010535:Laparoscopy; D011126:Polypropylenes; D019736:Prostheses and Implants; D013526:Surgical Mesh; D013537:Sutures; D013552:Swine
chemical_list: D011126:Polypropylenes