title: Visuospatial information processing in intoxicated, recently detoxified, and long-term abstinent alcoholics.
abstract: Visuospatial information processing has been shown to be particularly sensitive to acute alcohol intoxication and chronic alcohol abuse. This study extended previous studies by determining if recently detoxified alcoholics recover visuospatial processing after long-term abstinence. If visuospatial function returns to the level displayed by intoxicated alcoholics, then the deficit displayed by recently detoxified alcoholics may represent a short-term adjustment due to the removal of alcohol. However, if the visuospatial deficit remains in long-term abstinent alcoholics, then the superior processing of the intoxicated alcoholic could reflect a normalization of processing produced by alcohol ingestion. Twenty active and 40 recovering alcoholic male volunteers participated. The active alcoholics were seen intoxicated at the time of admission into a 21-day alcohol detoxification and treatment program. Of the recovering alcoholics, 20 were designated as recently detoxified alcoholics and had just completed the same treatment program. The remaining 20 long-term abstinent alcoholics had completed alcohol treatment several years previously with no relapse. Participants selected were similar in general demographic status, alcohol treatment histories, and psychomotor ability. Two main effects emerged from the results: First, the intoxicated alcoholics displayed visuospatial learning that was superior to the learning of alcoholics recently detoxified or abstinent for several years; a second principal finding was nearly identical visuospatial learning displayed by recently detoxified and long-term abstinent alcoholics.
authors.affiliation: Division of Psychology, Chapman University, Orange, CA 92666, USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Schandler
authors.forename: A D
authors.initials: AD
authors.lastname: Clegg
authors.forename: C S
authors.initials: CS
authors.lastname: Thomas
authors.forename: M J
authors.initials: MJ
authors.lastname: Cohen
mesh_terms: D000328:Adult; D000435:Alcoholic Intoxication / Q000523:psychology*; D000437:Alcoholism / Q000523:psychology / Q000534:rehabilitation*; D000431:Ethanol / Q000009:adverse effects* / Q000493:pharmacokinetics; D006801:Humans; D008297:Male; D011939:Mental Recall / Q000187:drug effects; D009949:Orientation / Q000187:drug effects*; D010153:Paired-Associate Learning / Q000187:drug effects; D010364:Pattern Recognition, Visual / Q000187:drug effects*; D011597:Psychomotor Performance / Q000187:drug effects*; D011930:Reaction Time / Q000187:drug effects; D013695:Temperance / Q000523:psychology*
chemical_list: D000431:Ethanol