Triphasic nephroblastoma in a horse.
A large abdominal mass in a 3-year-old filly was discovered clinically and removed and examined after the horse had been humanely killed. Histologically, three different tissue types were noted, occurring in equal amounts: epithelium largely in the form of well-differentiated tubules, multifocally distributed cell-dense foci of blastema, and myxoid to fibrous stroma. A diagnosis of triphasic nephroblastoma, a rare tumour in the horse, was made on the basis of microscopical findings. The finding of numerous glomeruloid structures confirmed the diagnosis and assisted in distinguishing the tumour from a teratoma. The histogenesis of nephroblastoma is briefly discussed in the context of the histological and immunohistochemical findings of the case.
Jardine
J E
JE
Department of Pathology, University of Pretoria, Onderstepoort, South Africa.
Nesbit
J W
JW
D000008:Abdominal Neoplasms / Q000473:pathology* / Q000662:veterinary*; D000818:Animals; D005260:Female; D006734:Horse Diseases / Q000473:pathology*; D006736:Horses; D009396:Wilms Tumor / Q000473:pathology* / Q000662:veterinary*