FISH mapping of centromere protein C (CENPC) on human chromosome 4q31-->q21.
Centromere protein C (CENP-C), a human centromere autoantigen, is a component of the inner kinetochore plate. CENP-C is required for maintaining proper kinetochore size and a timely transition to anaphase. In this study using fluorescence in situ hybridization to metaphase chromosomes, the human CENP-C gene (CENPC) was mapped on chromosome 4, region q13-->q21.
Xie
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Y
Biology Department, Hong Kong University of Science and Technology, Clearwater Bay, Kowloon, Hong Kong. boyxie@usthk.ust.hk
Heng
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HH
D002868:Chromosomal Proteins, Non-Histone / Q000235:genetics*; D002874:Chromosome Mapping; D002894:Chromosomes, Human, Pair 4 / Q000235:genetics*; D005796:Genes / Q000235:genetics; D006801:Humans; D017404:In Situ Hybridization, Fluorescence
D002868:Chromosomal Proteins, Non-Histone; C060905:centromere protein C