The use of mannitol in severe head injury. Brain Trauma Foundation.
Mannitol is effective in reducing ICP, and we recommend its use in the management of traumatic intracranial hypertension. Serum osmolalities greater than 320 mOSsm/L and hypovolemia should be avoided. Some data suggest that bolus administration is preferable to continuous infusion.
D000818:Animals; D001930:Brain Injuries / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D006259:Craniocerebral Trauma / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D004234:Diuretics, Osmotic / Q000627:therapeutic use*; D004285:Dogs; D004630:Emergencies; D006801:Humans; D007427:Intracranial Pressure; D016239:MEDLINE; D008353:Mannitol / Q000627:therapeutic use*; D011559:Pseudotumor Cerebri / Q000209:etiology / Q000517:prevention & control*
D004234:Diuretics, Osmotic; D008353:Mannitol