Antidepressant use during breastfeeding.
Women who suffer from postpartum depression require treatment. Caution must be exercised if any antidepressant is used. These agents concentrate in the central nervous system; therefore, serum concentrations and breastmilk: plasma ratios may not accurately predict infant drug exposure. Since there is no absolute contraindication to breastfeeding during antidepressant use, recommendations should be made on a case-by-case basis limited to healthy term infants. When possible plasma antidepressant concentrations, including metabolites, should be measured in the infant. Frequent developmental follow-up, not only during the treatment period but throughout childhood, should be performed on these infants.
Hatzopoulos
F K
FK
Albrecht
L M
LM
D000928:Antidepressive Agents / Q000009:adverse effects* / Q000145:classification / Q000493:pharmacokinetics; D001942:Breast Feeding; D005260:Female; D006801:Humans; D008895:Milk, Human / Q000187:drug effects
D000928:Antidepressive Agents