title: Tumour volume determination from MR images by morphological segmentation.
abstract: Accurate tumour volume measurement from MR images requires some form of objective image segmentation, and therefore a certain degree of automation. Manual methods of separating data according to the various tissue types which they are thought to represent are inherently prone to operator subjectivity and can be very time consuming. A segmentation procedure based on morphological edge detection and region growing has been implemented and tested on a phantom of known adjustable volume. Comparisons have been made with a traditional data thresholding procedure for the determination of tumour volumes on a set of patients with intracerebral glioma. The two methods are shown to give similar results, with the morphological segmentation procedure having the advantages of being automated and faster.
authors.affiliation: Department of Medical Physics, Royal Hull Hospitals NHS Trust, UK.
authors.forename: P
authors.initials: P
authors.lastname: Gibbs
authors.forename: D L
authors.initials: DL
authors.lastname: Buckley
authors.forename: S J
authors.initials: SJ
authors.lastname: Blackband
authors.forename: A
authors.initials: A
authors.lastname: Horsman
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D015588:Observer Variation; D019047:Phantoms, Imaging; D011336:Probability; D015203:Reproducibility of Results; D013238:Stereotaxic Techniques