Long-term bone marrow cultures in polycythaemia vera and essential thrombocythaemia.
Bone marrow samples of 8 patients with essential thrombocythaemia and three patients with polycythaemia vera were cultured in long-term bone marrow cultures. The production of non-adherent cells and colony-forming unit-granulocyte-macrophage harvested weekly did not differ from that of 29 healthy bone marrow transplant donors. There was a trend towards less complete stromal confluence in patients with a myeloproliferative disease.
Jantunen
R
R
Department of Medicine, Helsinki University Central Hospital, Finland.
Juvonen
E
E
Aimolahti
A
A
Ruutu
T
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001853:Bone Marrow / Q000378:metabolism*; D002478:Cells, Cultured; D005260:Female; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000302:isolation & purification; D006412:Hematopoietic Stem Cells / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011087:Polycythemia Vera / Q000378:metabolism*; D013922:Thrombocytosis / Q000378:metabolism*
D016178:Granulocyte-Macrophage Colony-Stimulating Factor