title: Epididymo-orchitis in an infant resulting from Escherichia coli urinary tract infection.
abstract: Epididymo-orchitis (EO) is said to be extremely rare in infants and children. It is usually diagnosed after scrotal exploration for symptoms which mimic manifestations between EO and torsion of the cord and its appendage. The pathophysiologic mechanisms for the development of EO are not well known. Although some causative agents of EO have been reported, in most cases there was no clear etiology. We report a 3-month-old male infant who had been well until the day prior to admission when irritability, left testicular swelling, scrotal erythema with a hot sensation were noted by his mother. He was treated medically after excluding the possibility of an emergent surgical condition (such as torsion of the cord and its appendage, or incarcerated hernia) by means of physical examinations, abdominal and inguino-scrotal sonography, laboratory studies, and testicular radionuclide scintigraphy. A catheterized sample of urine for culture yielded Escherichia coli. There was the possibility that the EO was caused by hematogenous rather than local spread from an infection of the urinary tract. He was treated with a 10-day course of intravenous cefazolin and amikacin. Following this, he improved clinically and a repeat catheterized urine sample remained sterile on culture. In addition, a bilateral inguinal hernia and hydrocele were detected by inguino-scrotal sonography and were operated on the 11th hospital day. He was discharged on the 16th day of hospitalization and remained well 11 months after discharge.
authors.affiliation: Department of Pediatrics, Tri-Service General Hospital, Taipei, Taiwan, R.O.C.
authors.forename: C F
authors.initials: CF
authors.lastname: Hsu
authors.forename: C C
authors.initials: CC
authors.lastname: Wang
authors.forename: C C
authors.initials: CC
authors.lastname: Chu
authors.forename: T Y
authors.initials: TY
authors.lastname: Chou
authors.forename: G Y
authors.initials: GY
authors.lastname: Diau
authors.forename: M L
authors.initials: ML
authors.lastname: Chu
mesh_terms: D003952:Diagnostic Imaging; D004823:Epididymitis / Q000175:diagnosis*; D004927:Escherichia coli Infections / Q000175:diagnosis*; D005260:Female; D006552:Hernia, Inguinal / Q000175:diagnosis; D006801:Humans; D007223:Infant; D008297:Male; D009920:Orchitis / Q000175:diagnosis*; D006848:Testicular Hydrocele / Q000175:diagnosis; D014552:Urinary Tract Infections / Q000175:diagnosis*