title: Fluoxetine in the treatment of depression in Asian (Chinese and Indian) patients in Singapore.
abstract: The aim of this paper is to study the efficacy and side-effects of fluoxetine. Fluoxetine is a specific serotonin reuptake inhibitor. Nineteen Asian (Chinese and Indian) patients who satisfied the DSM-3R criteria for major depressive episode were treated with fluoxetine 20 mg daily for 12 weeks. They were monitored two weekly. The results showed that during the period of treatment there was significant improvement in depressive symptoms and no serious side-effects. There were no significant changes in weight, temperature, blood pressure and pulse rate throughout the 12 weeks. This study showed that fluoxetine was well-tolerated and relieved the symptoms of depression effectively. Most of the results are supported by other studies.
authors.affiliation: Department of Psychological Medicine, National University Hospital, Singapore.
authors.forename: W F
authors.initials: WF
authors.lastname: Tsoi
authors.forename: C T
authors.initials: CT
authors.lastname: Tan
authors.forename: L P
authors.initials: LP
authors.lastname: Kok
mesh_terms: D000328:Adult; D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects / Q000627:therapeutic use*; D002681:China / Q000208:ethnology; D003866:Depressive Disorder / Q000188:drug therapy* / Q000208:ethnology / Q000523:psychology; D005006:Ethnicity / Q000523:psychology*; D005260:Female; D005473:Fluoxetine / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007194:India / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D012846:Singapore; D016896:Treatment Outcome
chemical_list: D018687:Antidepressive Agents, Second-Generation; D005473:Fluoxetine