Behcet's disease complicated with myelodysplastic syndrome: a report of two cases and review of the literature.
Two cases of Behcet's disease associated with myelodysplastic syndrome are described. Both patients showed a chromosomal abnormality, trisomy 8. Based on the laboratory findings in our patients and a careful review of the literature of similar cases, the association of the chromosomal abnormality with the pathogenesis of Behcet's disease is suggested.
Yano
K
K
First Department of Internal Medicine, Atomic Disease Institute Nagasaki University School of Medicine, Japan.
Eguchi
K
K
Migita
K
K
Takashima
H
H
Tamura
M
M
Izumino
K
K
Sasagawa
I
I
Sadamori
N
N
Nagataki
S
S
D000032:Abortion, Therapeutic; D000328:Adult; D000368:Aged; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D002898:Chromosomes, Human, Pair 8; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D011247:Pregnancy; D014314:Trisomy / Q000503:physiopathology