title: Endometrial carcinoma: dynamic MRI with turbo-FLASH technique.
abstract: OBJECTIVE
  Our goal was to investigate the usefulness of dynamic MRI with the turbo-FLASH technique in estimating myometrial invasion by endometrial carcinoma.
  
  
  METHODS
  Forty-six patients with endometrial carcinomas were evaluated with pathologic correlation. Dynamic MRI was performed with the rapid administration of Gd-DTPA using the turbo-FLASH technique.
  
  
  RESULTS
  The inner muscle layer showed more rapid contrast enhancement effects than the outer muscle layer even after menopause. Contrast-to-noise ratio between the inner muscle layer and endometrial carcinoma was maximum at approximately 50 s after administration of Gd-DTPA. In postmenopausal women, the accuracy in estimating myometrial invasion with T2-weighted images, contrast-enhanced T1-weighted images, and dynamic MRI was 66.7, 77.8, and 92.6%, respectively.
  
  
  CONCLUSIONS
  Dynamic MRI with the turbo-FLASH technique is considered to be a useful imaging method for the estimation of myometrial invasion by endometrial carcinoma, especially in postmenopausal patients.
authors.affiliation: Department of Radiology, Okayama University Medical School, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Joja
authors.forename: M
authors.initials: M
authors.lastname: Asakawa
authors.forename: T
authors.initials: T
authors.lastname: Asakawa
authors.forename: T
authors.initials: T
authors.lastname: Nakagawa
authors.forename: S
authors.initials: S
authors.lastname: Kanazawa
authors.forename: M
authors.initials: M
authors.lastname: Kuroda
authors.forename: I
authors.initials: I
authors.lastname: Togami
authors.forename: Y
authors.initials: Y
authors.lastname: Hiraki
authors.forename: N
authors.initials: N
authors.lastname: Akamatsu
authors.forename: T
authors.initials: T
authors.lastname: Kudo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D016889:Endometrial Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D004717:Endometrium / Q000473:pathology; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data; D008875:Middle Aged; D009215:Myometrium / Q000473:pathology / Q000503:physiopathology; D009361:Neoplasm Invasiveness; D017698:Postmenopause; D017697:Premenopause; D011446:Prospective Studies; D013997:Time Factors