[Acute necrotizing capillaritis in an adolescent dying from a a Goodpasture-like pulmonary-renal syndrome].
In this report the authors describe a rare case of pulmonary/renal syndrome like-Goodpasture's disease characterized by a necrotizing acute capillaritis in the lung, kidney, liver, spleen and heart. In the heart the capillaritis was associated with a contiguous acute ischemic lesion. The clinical and pathologic findings of the case suggest that the presence of vasculitis should not exclude a diagnosis of Goodpasture's Syndrome and that the multisystemic capillaritis would demonstrate the organ-non-specificity of anti-glomerular/alveolar basement membrane antibody.
Maresi
E
E
Istituto di Anatomia Patologica, Universit di Palermo.
Becchina
G
G
Orlando
E
E
Ottoveggio
G
G
D000208:Acute Disease; D000293:Adolescent; D019867:Anti-Glomerular Basement Membrane Disease / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D001327:Autoimmune Diseases / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D002196:Capillaries / Q000276:immunology / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D007668:Kidney / Q000098:blood supply* / Q000473:pathology; D008168:Lung / Q000098:blood supply* / Q000473:pathology; D008297:Male; D009336:Necrosis; D014657:Vasculitis / Q000150:complications* / Q000175:diagnosis / Q000276:immunology / Q000473:pathology