A nuclear magnetic resonance method for the determination of the purity of commercial dequalinium chloride.
4-amino-1-(10-4'-quinaldinylaminodecyl)quinaldinium chloride (3) has been identified through nuclear magnetic resonance (NMR) studies as one of the impurities of a commercial sample of dequalinium chloride (CAS 522-51-0). The NMR technique is proposed as a rapid method for the recognition and quantification of the impurities in dequalinium chloride samples.
Boschetti
C
C
Dipartimento di Chimica, Centro sullo Studio delle Sostanze Organiche Naturali, Milan, Italy.
Fronza
G
G
Fuganti
C
C
Grasselli
P
P
Magnone
A G
AG
Mele
A
A
Pellegatta
C
C
D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D003868:Dequalinium / Q000302:isolation & purification*; D004340:Drug Contamination; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D016339:Spectrometry, Mass, Fast Atom Bombardment
D003868:Dequalinium