Autologous fibrin adhesive in experimental tubal anastomosis.
OBJECTIVE
To evaluate autologous fibrin in rabbit oviduct anastomosis versus 7-0 vikryl, a conventional suture material used in tubal anastomosis.


METHODS
Thrombin was added to the autologous fibrinogen at the site of anastomosis to obtain a tissue adhesive. The anastomotic time, pregnancy rate, and litter size were evaluated. Three months later, a relaparotomy was done to evaluate patency and degree of adhesions, and a tubal biopsy was taken from the site of anastomosis.


RESULTS
Analysis of results showed a statistically significant (P < .001) shortened anastomotic time and superior histopathological union in the tissue adhesive group. Patency rate, pregnancy rate, and degree of adhesions were comparable in both groups.
Rajaram
S
S
Department of Obstetrics & Gynaecology, University College of Medical Sciences, Delhi, India.
Rusia
U
U
Agarwal
S
S
Agarwal
N
N
D000714:Anastomosis, Surgical; D000818:Animals; D005187:Fallopian Tubes / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D015718:Fibrin Tissue Adhesive; D006801:Humans; D008098:Litter Size; D008297:Male; D010784:Photomicrography; D011247:Pregnancy; D018873:Pregnancy Rate; D011817:Rabbits; D013537:Sutures; D013997:Time Factors; D000267:Tissue Adhesions; D014014:Tissue Adhesives
D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives