title: The factorial structure of schizotypy: Part II. Cognitive asymmetry, arousal, handedness, and sex.
abstract: We replicate relations between factors of schizotypy and cognitive asymmetry patterns assessed with recognition memory for words versus faces, and with arousal levels assessed with self-report scales. The withdrawn factor or subscales of loneliness and constricted affect were associated as before with a right hemisphere, face advantage asymmetry, as was physical anhedonia in males. Subjects with the opposite asymmetry and those high on the active factor--eccentricity and odd speech--had high self-report activation scores. These relations better characterized males who also had higher scores on the asymmetry-related factors. Females had higher scores on the third unreality factor--unusual perceptions and odd beliefs--which showed inconsistent relations with cognitive asymmetry. Non-right-handedness was associated with both hemisphere asymmetry patterns suggesting that the structural mechanism responsible for non-right-handedness is associated with bidirectional hemispheric functional imbalance. The results support the importance of patterns of functional asymmetry in underpinning different aspects of schizotypy.
authors.affiliation: Dept. of Psychiatry, Charing Cross and Westminster Medical School, University of London, England.
authors.forename: J H
authors.initials: JH
authors.lastname: Gruzelier
authors.forename: A
authors.initials: A
authors.lastname: Doig
mesh_terms: D000328:Adult; D001143:Arousal / Q000502:physiology; D002540:Cerebral Cortex / Q000503:physiopathology; D004292:Dominance, Cerebral / Q000502:physiology; D005163:Factor Analysis, Statistical; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008297:Male; D010555:Personality Inventory / Q000706:statistics & numerical data*; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data*; D011594:Psychometrics; D012016:Reference Values; D015203:Reproducibility of Results; D012559:Schizophrenia / Q000175:diagnosis* / Q000503:physiopathology; D012565:Schizophrenic Psychology; D012569:Schizotypal Personality Disorder / Q000175:diagnosis* / Q000503:physiopathology / Q000523:psychology; D012737:Sex Factors