title: Spore development in Bacillus subtilis.
abstract: Cell-cell and starvation signals are funneled through the phosphorelay to initiate sporulation by activating the transcription regulator SpoOA. Activation of SpoOA leads to synthesis of the transcription factors sigmaF and sigmaE. Substantial advances have been made in our understanding of the signal circuitry of the phosphorelay and of the cell-type-specific activation of the sigma factors.
authors.affiliation: Department of Microbiology and Immunology, Temple University School of Medicine, Philadelphia. Pennsylvania 19140, USA. piggot@astro.ocis.temple
authors.forename: P J
authors.initials: PJ
authors.lastname: Piggot
mesh_terms: D001412:Bacillus subtilis / Q000235:genetics / Q000502:physiology*; D001426:Bacterial Proteins / Q000378:metabolism; D002455:Cell Division; D015964:Gene Expression Regulation, Bacterial; D012808:Sigma Factor / Q000378:metabolism; D015398:Signal Transduction; D013171:Spores, Bacterial
chemical_list: D001426:Bacterial Proteins; C064971:FliA protein, Bacteria; D012808:Sigma Factor