Biodegradation of 4-chlorophenol via a hydroquinone pathway by Arthrobacter ureafaciens CPR706.
A newly isolated Arthrobacter ureafaciens, strain CPR706, could degrade 4-chlorophenol via a new pathway, in which the chloro-substituent was eliminated in the first step and hydroquinone was produced as a transient intermediate. Strain CPR706 exhibited much higher substrate tolerance and degradation rate than other strains that degraded 4-chlorophenol by the hydroxylation at the second carbon position to form chlorocatechol. Strain CPR706 could also degrade other para-substituted phenols (4-nitro-, 4-bromo-, 4-iodo-, and 4-fluoro-phenol) via the hydroquinone pathway.
Bae
H S
HS
Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Taejun, South Korea.
Lee
J M
JM
Lee
S T
ST
D001173:Arthrobacter / Q000378:metabolism*; D002733:Chlorophenols / Q000378:metabolism* / Q000494:pharmacology; D006873:Hydroquinones / Q000378:metabolism*; D009153:Mutagens / Q000378:metabolism*; D010636:Phenols / Q000378:metabolism; D011549:Pseudomonas / Q000378:metabolism; D013379:Substrate Specificity
D002733:Chlorophenols; D006873:Hydroquinones; D009153:Mutagens; D010636:Phenols; C029107:4-chlorophenol; C031927:hydroquinone