title: Immunohistochemical localisation of carcinoembryonic antigen (CEA) in malignant epithelial ovarian tumours using monoclonal antibodies.
abstract: The localization of carcinoembryonic antigen (CEA) in malignant epithelial ovarian tumours was studied using immunohistochemistry. The tissue included in the study consisted of 38 ovarian cancers : 14 mucinous adenocarcinomas, 23 serous adenocarcinomas and 1 endometroid carcinoma. Peroxidase-antiperoxidase staining technique using monoclonal antibodies to CEA was used on routinely fixed paraffin embedded tissues. CEA positivity was observed in all (100%) mucinous adenocarcinomas whereas only one case of serous cyst a denocarcinoma (4.3%) was weakly positive. The only case endometroid carcinoma encountered showed patchy CEA positivity.
authors.affiliation: Department of Pathology, B.J. Medical College, Pune.
authors.forename: N
authors.initials: N
authors.lastname: Gogate
authors.forename: S
authors.initials: S
authors.lastname: Deshmukh
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000276:immunology; D000911:Antibodies, Monoclonal; D002272:Carcinoembryonic Antigen / Q000378:metabolism*; D018269:Carcinoma, Endometrioid / Q000276:immunology; D018284:Cystadenocarcinoma, Serous / Q000276:immunology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D010051:Ovarian Neoplasms / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D002272:Carcinoembryonic Antigen