A practical synthesis from siastatin B of (3S,4S,5R,6R)- 4,5-dihydroxy-6-(trifluoroacetamido)piperidine-3-carboxylic acid having antimetastatic activity in mice.
Satoh
T
T
Institute of Microbial Chemistry, Tokyo, Japan.
Nishimura
Y
Y
Kondo
S
S
Takeuchi
T
T
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors; D050111:Imino Sugars; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D008968:Molecular Conformation; D015394:Molecular Structure; D009362:Neoplasm Metastasis / Q000517:prevention & control; D009557:Nipecotic Acids / Q000138:chemical synthesis* / Q000494:pharmacology; D010880:Piperidines
D000970:Antineoplastic Agents; D050111:Imino Sugars; D009557:Nipecotic Acids; D010880:Piperidines; C099337:6-(trifluoroacetamido)-4,5-dihydroxypiperidine-3-carboxylic acid; C011353:siastatin; D006026:Glycoside Hydrolases