title: Prenatal ultrasonographic diagnosis of fetal hydrocephalus due to infection with parainfluenza virus type 3.
abstract: Parainfluenza virus type 3 is one of the most common causes of respiratory infection in infants. No complications of pregnancy or fetal anomalies have been reported in association with parainfluenza virus infection. A pregnancy was terminated at 22 weeks' gestation due to ultrasonographic diagnosis of hydrocephalus. Pathological examination was consistent with viral encephalitis, ventriculitis and pneumonia. Serological investigation demonstrated a significant rise in maternal antibody titers for parainfluenza virus type 3. Parainfluenza virus type 3 may be associated with severe fetal infection in the first half of pregnancy. Serological studies for this virus should be considered in cases of fetal hydrocephalus.
authors.affiliation: Department of Obstetrics and Gynecology, The Chaim Sheba Medical Center, Tel Hashomer, Israel.
authors.forename: D S
authors.initials: DS
authors.lastname: Seidman
authors.forename: D
authors.initials: D
authors.lastname: Nass
authors.forename: E
authors.initials: E
authors.lastname: Mendelson
authors.forename: I
authors.initials: I
authors.lastname: Shehtman
authors.forename: S
authors.initials: S
authors.lastname: Mashiach
authors.forename: R
authors.initials: R
authors.lastname: Achiron
mesh_terms: D000032:Abortion, Therapeutic; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D010224:Parainfluenza Virus 3, Human / Q000276:immunology*; D018184:Paramyxoviridae Infections / Q000175:diagnosis* / Q000635:transmission; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D016216:Ultrasonography, Prenatal
chemical_list: D000914:Antibodies, Viral