title: Hearing and Sjögren's syndrome.
abstract: Immune sensorineural hearing loss is manifested in several systemic immune diseases. Although hearing loss has been previously documented in patients with Sjögren's syndrome (SS), the effect of SS on hearing is unclear. This prospective study was designed to assess the presence of hearing loss in 14 patients with SS and, if sensorineural hearing loss was present, to determine if the hearing loss was immune-mediated. Patients were evaluated with basic audiologic tests as well as for cellular immune inner ear reactivity as measured by the lymphocyte transformation test (LTT). Three patients had evidence of sensorineural hearing loss. Two patients had a positive LTT without evidence of sensorineural hearing loss. This preliminary study suggests that SS may not directly cause sensorineural hearing loss, immuno-mediated or otherwise.
authors.affiliation: Cleveland Clinic Foundation, Department of Otolaryngology and Communicative Disorders, Ohio, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Trott
authors.forename: G B
authors.initials: GB
authors.lastname: Hughes
authors.forename: L H
authors.initials: LH
authors.lastname: Calabrese
authors.forename: B P
authors.initials: BP
authors.lastname: Barna
authors.forename: R H
authors.initials: RH
authors.lastname: Nodar
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D006801:Humans; D008213:Lymphocyte Activation; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012859:Sjogren's Syndrome / Q000150:complications*