title: Visual recovery following treatment with very high dose corticosteroid in traumatic optic neuropathy.
abstract: Optic nerve compression is a true ophthalmic emergency. In addition to causes such as tumours, infection, mucoceles and granulomas, the majority of cases are the result of orbitofacial or closed-head trauma. The appropriate management of such cases is controversial; with some authors favouring surgical decompression while others advocate medical treatment using very high-dose corticosteroids, or a combination of both. We report a case of traumatic optic neuropathy in which there was marked improvement in visual acuity following the administration of methylprednisolone.
authors.affiliation: Department of Ophthalmology, National University Hospital, Singapore.
authors.forename: T K
authors.initials: TK
authors.lastname: Chan
authors.forename: J S
authors.initials: JS
authors.lastname: Wong
authors.forename: R S
authors.initials: RS
authors.lastname: Ram
authors.forename: S
authors.initials: S
authors.lastname: Amrith
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006259:Craniocerebral Trauma / Q000150:complications*; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D018917:Optic Neuropathy, Ischemic / Q000188:drug therapy* / Q000209:etiology; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D014792:Visual Acuity
chemical_list: D000893:Anti-Inflammatory Agents; D018696:Neuroprotective Agents; D011239:Prednisolone; D008775:Methylprednisolone