title: Effect of education and gender adjustment on the sensitivity and specificity of a cognitive screening battery for dementia: results from the MoVIES Project. Monongahela Valley Independent Elders Survey.
abstract: The Monongahela Valley Independent Elders Survey (MoVIES) used a multiphase process to identify demented persons among 1,366 randomly selected noninstitutionalized individuals 65 years and older. Raw test scores from a cognitive screening battery were used to identify cognitively impaired individuals who were referred for a clinical evaluation. Subsequently, test scores were adjusted for education and gender within age strata. Adjusting test scores affected sensitivity for dementia only among the most educated, increasing sensitivity among younger subjects and decreasing among the older subjects. Specificity increased among the least educated and the oldest subjects. Overall, the adjusted criteria did not perform as well as the unadjusted criteria in this sample. Adjustment for education will not necessarily improve the ability of a screening battery for cognitive function to identify demented persons, particularly if unadjusted scores perform well.
authors.affiliation: University of Pittsburgh, Graduate School of Public Health, Department of Epidemiology, Pa 15261, USA.
authors.forename: S H
authors.initials: SH
authors.lastname: Belle
authors.forename: E C
authors.initials: EC
authors.lastname: Seaberg
authors.forename: M
authors.initials: M
authors.lastname: Ganguli
authors.forename: G
authors.initials: G
authors.lastname: Ratcliff
authors.forename: S
authors.initials: S
authors.lastname: DeKosky
authors.forename: L H
authors.initials: LH
authors.lastname: Kuller
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D003704:Dementia / Q000175:diagnosis / Q000453:epidemiology*; D004522:Educational Status; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008403:Mass Screening / Q000706:statistics & numerical data*; D008609:Mental Status Schedule / Q000706:statistics & numerical data; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D010414:Pennsylvania / Q000453:epidemiology; D011594:Psychometrics; D012494:Sampling Studies; D012680:Sensitivity and Specificity