title: [Rational use of antidepressants in general medicine].
abstract: Depression is a common cause of morbidity and is frequently recurrent. Therefore, treatment must be oriented more and more to the prevention of relapses in addition to the cure of depressive episodes. Long-term administration of antidepressant drugs becomes thus the rule and, as a consequence, general practitioners are increasingly concerned by the prescription of such medications. The choice of an antidepressant is mostly oriented by the side-effects profile of the pharmacological class of the compound. Fortunately, more recent drugs like SSRIs (selective serotonin reuptake inhibitors) and reversible MAOIs (monoamine inhibitors) have a very higher security index than tricyclics and classical MAOIs.
authors.affiliation: Institut de Psychiatrie et de Psychologie Médicale, Centre Hospitalier Universitaire Brugmann, Bruxelles.
authors.forename: P
authors.initials: P
authors.lastname: Verbanck
authors.forename: P
authors.initials: P
authors.lastname: Cnockaert
mesh_terms: D000368:Aged; D000928:Antidepressive Agents / Q000009:adverse effects / Q000145:classification / Q000494:pharmacology / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000188:drug therapy*; D004347:Drug Interactions; D005194:Family Practice; D006801:Humans; D007668:Kidney / Q000187:drug effects; D008099:Liver / Q000187:drug effects; D008996:Monoamine Oxidase Inhibitors / Q000009:adverse effects
chemical_list: D000928:Antidepressive Agents; D008996:Monoamine Oxidase Inhibitors