[Experience in the use of eiconol (a complex of unsaturated fatty acids) in non-insulin-dependent diabetes mellitus].
Cardiovascular disease is the principal cause of morbidity, functional disability and fatal outcomes in patients with non-insulin-dependent diabetes mellitus (NIDDM). The results of administration of eikonol, food additive containing omega-3 unsaturated fatty acids, for 3 months were analyzed for 60 elderly NIDDM patients with ischemic heart disease. A single administration of eikonol leads to a decrease in accumulation of intracellular cholesterol by 15%. Diet eikonol decreased the level of total cholesterol and triglycerides in the blood by 23 and 43%, respectively. Moreover, the higher is the initial value of these parameters, the higher is the effect of the preparation. Eikonol proved to increase the level of lipoproteins of high density, produced a positive trends in NIDDM clinical picture. Food additive eikonol is recommended for wide administration in elderly NIDDM patients with atherogenic dyslipidemias.
Lazebnik
L B
LB
Vertkin
A L
AL
Malichenko
S B
SB
Li
E D
ED
Konev
Iu V
IuV
Romanovskaia
T V
TV
Goncharov
L F
LF
D000368:Aged; D000369:Aged, 80 and over; D002784:Cholesterol / Q000097:blood; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000628:therapy*; D004042:Dietary Fats, Unsaturated / Q000627:therapeutic use*; D005260:Female; D005395:Fish Oils / Q000627:therapeutic use*; D005503:Food Additives; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use*; D008075:Lipoproteins, HDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
D004042:Dietary Fats, Unsaturated; D005395:Fish Oils; D005503:Food Additives; D000960:Hypolipidemic Agents; D008075:Lipoproteins, HDL; D014280:Triglycerides; C089938:eiconol; D002784:Cholesterol