title: [Effect of components of virus-containing allantoic fluid on the stability of influenza virus during storage].
abstract: Effects of allantoic fluid fractions (isolated by sedimentation and gel chromatography) on inactivation of influenza virus and lipid peroxidation in viral envelopes and phospholipid liposomes indicate the presence of both components with prooxidant effects enhancing inactivation and of endogenous antioxidants stabilizing the viral activity. The hypothesized "lipid" mechanism of inactivation (suggesting activation of lipid peroxidation in viral envelopes followed by inactivation of viral nucleoprotein) permits a satisfactory interpretation of viral material inactivation.
authors.forename: V D
authors.initials: VD
authors.lastname: Poryvaev
authors.forename: T G
authors.initials: TG
authors.lastname: Viatkina
authors.forename: A B
authors.initials: AB
authors.lastname: Ryzhikov
authors.forename: A N
authors.initials: AN
authors.lastname: Sergeev
authors.forename: S R
authors.initials: SR
authors.lastname: Iagofarov
mesh_terms: D000482:Allantois / Q000378:metabolism / Q000821:virology*; D000818:Animals; D000998:Antiviral Agents; D002642:Chick Embryo; D009980:Influenza A virus / Q000302:isolation & purification* / Q000378:metabolism; D015227:Lipid Peroxidation; D008081:Liposomes; D010743:Phospholipids / Q000378:metabolism; D017382:Reactive Oxygen Species; D014759:Viral Envelope Proteins / Q000378:metabolism
chemical_list: D000998:Antiviral Agents; D008081:Liposomes; D010743:Phospholipids; D017382:Reactive Oxygen Species; D014759:Viral Envelope Proteins