Reactions of hydrated formaldehyde in nasal mucus.
Formaldehyde is a well known toxic air impurity affecting the upper respiratory tract. It rapidly forms methylene glycol in water. Reactions of the hydrated formaldehyde with nasal mucus were studied by C-13 NMR spectroscopy. In the NMR spectra methylene glycol dominated and only minor signals from possible reactions were observed. This finding suggests that nasal mucus effectively protects nasal epithelium against formaldehyde.
Priha
E
E
Tampere Regional Institute of Occupational Health, Finland.
Liesivuori
J
J
Santa
H
H
Laatikainen
R
R
D002247:Carbon Isotopes; D005557:Formaldehyde / Q000378:metabolism*; D006018:Glycols / Q000378:metabolism; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D009093:Mucus / Q000378:metabolism*; D009297:Nasal Mucosa / Q000378:metabolism*
D002247:Carbon Isotopes; D006018:Glycols; D005557:Formaldehyde