title: [Development of replacement meniscus of autogenous tissue].
abstract: At present no established therapy for the complete loss of meniscus is available. An attempt is made to create a transplant out of autogeneic tissue resembling the meniscus in its morphological and functional aspects. The middle third of the patellar tendon with proximal and distal bone blocks serves as a basis and is coated with a fascia lata strip. After temporary subcutaneous transfer, the meniscus substitute is intended for later transplantation. The theoretical ideas for the imitation of a meniscus in view of fibre architecture and biomechanical validity were tested in 14 sheep. In principal this model succeeds in imitating the fibre architecture of the menisci. After a conditioning period of 8-10 weeks in the subcutaneous tissue, the neomeniscus seems to be suitable for transplantation. The tensile strength of the grafts decreases slightly but the bone blocks stay viable.
authors.affiliation: Abteilung für Allgemein- und Unfallchirurgie des Städtischen Krankenhauses München-Bogenhausen.
authors.forename: G
authors.initials: G
authors.lastname: Metak
authors.forename: M A
authors.initials: MA
authors.lastname: Scherer
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D005206:Fascia Lata / Q000473:pathology / Q000637:transplantation*; D006801:Humans; D007718:Knee Injuries / Q000473:pathology / Q000601:surgery*; D008592:Menisci, Tibial / Q000473:pathology / Q000601:surgery; D008855:Microscopy, Electron, Scanning; D012756:Sheep; D013709:Tendon Transfer / Q000379:methods*; D000070600:Tibial Meniscus Injuries; D016896:Treatment Outcome