[Visceral larva migrans. A rare cause of eosinophilia in adults].
Toxocariasis is a cosmopolitan infection of dogs and cats with a roundworm resembling Ascaris. Man becomes infected by ingesting eggs from the environment. The infection occurs mainly in children. There are two distinct syndromes: visceral larva migrans and ocular toxocariasis. The author describes the case of a 70 year old Norwegian female with visceral larva migrans. One month after a visit to Spain she developed fever, hepatomegaly and marked eosinophilia. Liver biopsy revealed subacute hepatitis with eosinophilic leucocyte infiltration. Toxocara ELISA was strongly positive. Treatment with albendazol 400 mg b.i.d. and prednisone 10 mg daily for three weeks was successful. A clinical relapse after three months was treated in the same way for one month. Prolonged treatment is recommended. To our knowledge, this is the first reported case of visceral larva migrans in an adult Norwegian. Epidemiology, diagnosis and treatment are discussed.
Lund-Tønnesen
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Infeksjonsseksjonen Medisinsk avdeling, Haukeland Sykehus 5021, Bergen.
D000368:Aged; D000818:Animals; D002415:Cats; D004285:Dogs; D004797:Enzyme-Linked Immunosorbent Assay; D004802:Eosinophilia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D007816:Larva Migrans, Visceral / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D009664:Norway / Q000453:epidemiology; D011860:Radiography, Abdominal; D013030:Spain / Q000453:epidemiology; D014057:Tomography, X-Ray Computed; D014195:Travel; D015047:Zoonoses