title: Spermatocytic seminoma: a clinicopathological review of ten patients.
abstract: Spermatocytic seminoma is an uncommon variety of testicular neoplasm, differing from its classical counterpart at both clinical and pathological levels and having a low propensity to metastasize. This is a retrospective review of ten patients with pathologically confirmed and reviewed disease who were seen at the Royal Marsden Hospital. All patients presented as Stage I. Five were treated with radiotherapy and five have undergone surveillance. The median age was 56.5 years. The median follow-up is 8 years and no patient has relapsed. Two have died of intercurrent disease. Our series supports others of a similar size in the literature with respect to both the rarity and the good prognosis of spermatocytic seminoma. With only one case of relapse confirmed in the literature, this is a subgroup of patients in whom radiotherapy can safely be omitted.
authors.affiliation: Royal Prince Alfred Hospital, Sydney, Australia.
authors.forename: S
authors.initials: S
authors.lastname: Pendlebury
authors.forename: A
authors.initials: A
authors.lastname: Horwich
authors.forename: D P
authors.initials: DP
authors.lastname: Dearnaley
authors.forename: J
authors.initials: J
authors.lastname: Nicholls
authors.forename: C
authors.initials: C
authors.lastname: Fisher
mesh_terms: D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009919:Orchiectomy; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy; D018239:Seminoma / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D013736:Testicular Neoplasms / Q000473:pathology* / Q000532:radiotherapy / Q000601:surgery; D013737:Testis / Q000473:pathology*; D013997:Time Factors