title: Frequency of phasic wave contraction is variable during long-term sphincter of Oddi manometry.
abstract: OBJECTIVE
  The sphincter of Oddi (SO) manometry via the transpapillary route is performed usually for a period of several minutes. To investigate whether there is a considerable variation in the manometric measurements of SO over a longer period of time, we have performed long-term manometry of SO via the transpapillary (n = 5) as well as the percutaneous (n = 7) routes.
  
  
  METHODS
  Transpapillary manometry of SO was carried out by a conventional low-compliant continuously perfused technique. The location of the manometric catheter was maintained at the same level by observing the video monitor. SO manometry and the duodenal migrating motor complex (MMC) was simultaneously measured with a specially designed catheter via the percutaneous route.
  
  
  RESULTS
  The mean recording time was 41 min (range 11-72 min). The frequency of phasic contractions of SO varied from 0 to 12/min. Throughout the entire recording period, high-frequency contractions (over 8/min) were noted 14.9% of the time. In the cases of percutaneous transductal SO manometry, the periods of high-frequency contractions coincided with phase III of duodenal MMC. The interval between the first high-frequency contractions and the second was 47 min. The mean duration of high-frequency contractions was 6 min and 42 s. There was no significant change in the amplitude, basal pressure, and contraction sequence among the various periods of frequencies.
  
  
  CONCLUSIONS
  Long-term continuous recording of SO manometry via the transpapillary and percutaneous routes showed that the contraction frequency of SO was not constant and tachyoddia appeared periodically. In the interpretation of tachyoddia, it is necessary to consider the period of phase III of the duodenal MMC.
authors.affiliation: Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
authors.forename: S K
authors.initials: SK
authors.lastname: Lee
authors.forename: M H
authors.initials: MH
authors.lastname: Kim
authors.forename: D W
authors.initials: DW
authors.lastname: Seo
authors.forename: B M
authors.initials: BM
authors.lastname: Yoo
authors.forename: M H
authors.initials: MH
authors.lastname: Lee
authors.forename: S J
authors.initials: SJ
authors.lastname: Myung
authors.forename: Y I
authors.initials: YI
authors.lastname: Min
mesh_terms: D001653:Bile Ducts, Intrahepatic; D002769:Cholelithiasis / Q000503:physiopathology; D004386:Duodenum / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry / Q000379:methods; D008875:Middle Aged; D009119:Muscle Contraction / Q000502:physiology; D016065:Myoelectric Complex, Migrating / Q000502:physiology; D009803:Sphincter of Oddi / Q000502:physiology*; D013997:Time Factors