title: Benzophenone synthase from cultured cells of Centaurium erythraea.
abstract: A central step in xanthone biosynthesis is the formation of the C13 skeleton, i.e. an intermediate benzophenone. Biosynthesis of 2,3',4,6-tetrahydroxybenzophenone from m-hydroxybenzoyl-CoA and malonyl-CoA was shown in cell-free extracts from cultured cells of Centaurium erythraea. The enzyme catalyzing this reaction was named benzophenone synthase.
authors.affiliation: Institut für Pharmazeutische Biologie, Bonn, Germany.
authors.forename: L
authors.initials: L
authors.lastname: Beerhues
mesh_terms: D000214:Acyl Coenzyme A / Q000378:metabolism; D019735:Carbon-Carbon Ligases; D002474:Cell-Free System; D002478:Cells, Cultured; D004229:Dithiothreitol / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008025:Ligases / Q000302:isolation & purification / Q000378:metabolism*; D010944:Plants / Q000201:enzymology*; D013379:Substrate Specificity; D013816:Thermodynamics
chemical_list: D000214:Acyl Coenzyme A; D008025:Ligases; D019735:Carbon-Carbon Ligases; C098887:benzophenone synthase; D004229:Dithiothreitol