title: 3-Hydroxypropionaldehyde, an inhibitory metabolite of glycerol fermentation to 1,3-propanediol by enterobacterial species.
abstract: Glycerol fermentation by Enterobacter agglomerans revealed that both growth and 1,3-propanediol production ceased after consumption of about 430 mM glycerol, irrespective of the initial glycerol content. This phenomenon was assigned to the production of 3-hydroxypropionaldehyde, which was identified by proton nuclear magnetic resonance and which showed a bacteriostatic effect. The accumulation during glycerol fermentation was also observed with two other enterobacterial species, i.e., Klebsiella pneumoniae and Citrobacter freundii.
authors.affiliation: Laboratoire de Biotechnologie de l'Environnement, Institut National de la Recherche Agronomique, Narbonne, France.
authors.forename: F
authors.initials: F
authors.lastname: Barbirato
authors.forename: J P
authors.initials: JP
authors.lastname: Grivet
authors.forename: P
authors.initials: P
authors.lastname: Soucaille
authors.forename: A
authors.initials: A
authors.lastname: Bories
mesh_terms: D000447:Aldehydes; D016971:Citrobacter freundii / Q000378:metabolism; D004754:Enterobacter / Q000378:metabolism; D004755:Enterobacteriaceae / Q000187:drug effects / Q000378:metabolism*; D005285:Fermentation / Q000187:drug effects; D005985:Glyceraldehyde / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000378:metabolism / Q000494:pharmacology; D005990:Glycerol / Q000378:metabolism*; D007711:Klebsiella pneumoniae / Q000378:metabolism; D011407:Propane; D011409:Propylene Glycols / Q000378:metabolism*
chemical_list: D000447:Aldehydes; D011409:Propylene Glycols; C047158:3-hydroxypropionaldehyde; D005985:Glyceraldehyde; C041787:1,3-propanediol; D005990:Glycerol; D011407:Propane