title: [Simultaneous allotransplantation of the adrenal gland and the kidney].
abstract: Thirteen months after a bilateral nephrectomy for a synchronous bilateral renal cell carcinoma involving both adrenal glands, a 46 years-old man underwent a simultaneous adrenal and kidney allotransplantation. The left renal allograft was harvested together with a ipsilateral adrenal gland using a common aortic patch. Maintenance immunosuppression was based on azathioprine, antilymphocyte globulin cyclosporine and prednisolone. Kidney allograft function remained stable for 5 years until the patient died from multifocal pancreatic metastases. Clinical, biochemical, radiological and histological arguments demonstrated the function of adrenal allograft. To our knowledge, it is the first report of a simultaneous kidney and adrenal gland allotransplantation in a therapeutic intent. An adrenal gland allotransplantation is only justified when the adrenal insufficiency exists with an end stage organ failure requiring transplantation and therefore immunosuppressive drugs.
authors.affiliation: Service d'Urologie et de Chirurgie de la Transplantation, hôpital E.-Herriot, Lyon.
authors.forename: J M
authors.initials: JM
authors.lastname: Dubernard
authors.forename: P
authors.initials: P
authors.lastname: Cloix
authors.forename: L C
authors.initials: LC
authors.lastname: Feitosa-Tajra
authors.forename: F
authors.initials: F
authors.lastname: Borson-Chazot
authors.forename: B
authors.initials: B
authors.lastname: Bancel
authors.forename: J
authors.initials: J
authors.lastname: Baulieux
authors.forename: X
authors.initials: X
authors.lastname: Martin
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000556:secondary / Q000601:surgery; D000311:Adrenal Glands / Q000637:transplantation*; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology / Q000601:surgery; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D014184:Transplantation, Homologous