title: Kurasoins A and B, new protein farnesyltransferase inhibitors produced by Paecilomyces sp. FO-3684. I. Producing strain, fermentation, isolation, and biological activities.
authors.affiliation: Research Center for Biological Function, Kitasato Institute, Tokyo, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Uchida
authors.forename: K
authors.initials: K
authors.lastname: Shiomi
authors.forename: J
authors.initials: J
authors.lastname: Inokoshi
authors.forename: R
authors.initials: R
authors.lastname: Masuma
authors.forename: T
authors.initials: T
authors.lastname: Kawakubo
authors.forename: H
authors.initials: H
authors.lastname: Tanaka
authors.forename: Y
authors.initials: Y
authors.lastname: Iwai
authors.forename: S
authors.initials: S
authors.lastname: Omura
mesh_terms: D019883:Alkyl and Aryl Transferases; D004791:Enzyme Inhibitors / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D051231:Farnesyltranstransferase; D005285:Fermentation; D007211:Indoles / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D010143:Paecilomyces / Q000145:classification / Q000378:metabolism*; D010636:Phenols / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014166:Transferases / Q000037:antagonists & inhibitors*
chemical_list: D004791:Enzyme Inhibitors; D007211:Indoles; D010636:Phenols; C102430:kurasoin A; C102431:kurasoin B; D014166:Transferases; D019883:Alkyl and Aryl Transferases; D051231:Farnesyltranstransferase