Recombinant protein production in transgenic animals.
The engineering of animals for recombinant protein production has gone beyond the stage of identifying proper regulatory sequences. Efforts are now spent on the generation of transgenic animals that process heterologous proteins more efficiently. Another line of research is the development of strategies aimed at bypassing pronuclear microinjection.
Echelard
Y
Y
Genzyme Transgenics Corporation, One Mountain Road, Framingham, MA 01701-9322, USA. ypgrech@world.std.com
D000818:Animals; D030801:Animals, Genetically Modified / Q000235:genetics* / Q000378:metabolism*; D001709:Biotechnology; D001798:Blood Proteins / Q000096:biosynthesis / Q000235:genetics; D018076:DNA, Complementary / Q000008:administration & dosage / Q000235:genetics; D005260:Female; D006801:Humans; D008321:Mammary Glands, Animal / Q000378:metabolism; D008845:Microinjections; D011994:Recombinant Proteins / Q000096:biosynthesis* / Q000235:genetics*
D001798:Blood Proteins; D018076:DNA, Complementary; D011994:Recombinant Proteins