title: [Immuno-hemolytic transfusion reactions. III. Report of 61 cases].
abstract: Blood transfusion is mainly bound to immunological and infectious risks. The immunological risk originates from an incompatibility between the blood of the donor and that of the recipient; this risk remains insufficiently assessed. A multicentre study has been carried out by the French Blood Transfusion Society and the National Institute for Blood Transfusion. Sixty-one accidents due to an erythrocyte incompatibility were found: 26 cases with ABO incompatibility, and 35 cases with alloantibodies of other blood group systems. For the former category of accidents, the most frequent cause was due to a failure in the realization of the bedside ABO check. For the latter, the main problem was the achievement and the interpretation of antibody screening. The long term follow-up shows no chronic after-effects of immunological accidents. For each accident, errors have been identified and analysed. It was proven that they all originate from health care establishments.
authors.affiliation: Centre National de Référence pour les Groupes Sanguins, Institut National de la Transfusion Sanguine, Paris, France.
authors.forename: P Y
authors.initials: PY
authors.lastname: Le Pennec
authors.forename: A M
authors.initials: AM
authors.lastname: Tissier
authors.forename: L
authors.initials: L
authors.lastname: Mannessier
authors.forename: O
authors.initials: O
authors.lastname: Agulles
authors.forename: J
authors.initials: J
authors.lastname: Babinet
authors.forename: M L
authors.initials: ML
authors.lastname: Bidet
authors.forename: D
authors.initials: D
authors.lastname: Bombail-Girard
authors.forename: J J
authors.initials: JJ
authors.lastname: Cabaud
authors.forename: J
authors.initials: J
authors.lastname: Cartron
authors.forename: J
authors.initials: J
authors.lastname: Chiaroni
authors.forename: C
authors.initials: C
authors.lastname: Desaint
authors.forename: C
authors.initials: C
authors.lastname: Krause
authors.forename: B
authors.initials: B
authors.lastname: Lamy
authors.forename: F
authors.initials: F
authors.lastname: Meyer
authors.forename: R
authors.initials: R
authors.lastname: Mortelecque
authors.forename: S
authors.initials: S
authors.lastname: Nafissi
authors.forename: P
authors.initials: P
authors.lastname: Rasongles
authors.forename: B
authors.initials: B
authors.lastname: Schweitzer
authors.forename: P
authors.initials: P
authors.lastname: Rouger
mesh_terms: D000017:ABO Blood-Group System / Q000276:immunology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001787:Blood Group Incompatibility; D001793:Blood Preservation; D019411:Clinical Laboratory Techniques; D004912:Erythrocytes / Q000276:immunology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007518:Isoantibodies / Q000097:blood; D008297:Male; D019300:Medical Errors; D008875:Middle Aged; D018570:Risk Assessment; D065227:Transfusion Reaction
chemical_list: D000017:ABO Blood-Group System; D007518:Isoantibodies