title: [Cervical metastasis of squamous cell carcinoma of unknown origin: experience at Hospital de Sant Pau, Barcelona, Spain].
abstract: Between 1984 and 1992, 18 cases of cervical metastasis of squamous cell or anaplastic carcinoma (1% of all head and neck tumors) were seen at the Hospital de la Santa Creu i Sant Pau (Barcelona, Spain). Fifteen patients underwent radical surgery: 1 N1, 4 N2A and 10N3, N1 and N2A patients underwent surgery followed by radiotherapy. The 10 N3 patients began with neoadjuvant chemotherapy (cisplatin and 5-fluorouracil), then 8 had radical neck dissection and 2 had palliative radiotherapy. The primary tumor was found in 11%. The 5-year survival rate was 40% in N1+2A and 11% in N3. Chemotherapy did not improve survival in advanced disease, but it facilitated neck dissection and selection of the group with the prognosis.
authors.affiliation: Servicio de ORL, Hospital de la Santa Creu i Sant Pau, (HSCSP), Universitat Autónoma de Barcelona.
authors.forename: A
authors.initials: A
authors.lastname: Jürgens Mestre
authors.forename: M
authors.initials: M
authors.lastname: Quer Agusti
authors.forename: D
authors.initials: D
authors.lastname: Agudelo García
authors.forename: E
authors.initials: E
authors.lastname: Trías Mis
authors.forename: X
authors.initials: X
authors.lastname: León Vintro
authors.forename: A
authors.initials: A
authors.lastname: López Pousa
authors.forename: M
authors.initials: M
authors.lastname: Vega Masana
authors.forename: P
authors.initials: P
authors.lastname: de las Heras Durán
authors.forename: J
authors.initials: J
authors.lastname: Burgués Vila
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000453:epidemiology* / Q000601:surgery; D002574:Cervical Vertebrae / Q000473:pathology*; D002945:Cisplatin / Q000627:therapeutic use; D005260:Female; D005472:Fluorouracil / Q000627:therapeutic use; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000453:epidemiology* / Q000601:surgery; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011878:Radiotherapy; D012737:Sex Factors; D013030:Spain / Q000453:epidemiology
chemical_list: D000970:Antineoplastic Agents; D002945:Cisplatin; D005472:Fluorouracil