title: The heritage of hepatitis B vaccine.
abstract: Pioneering development of the plasma-derived and yeast-derived recombinant hepatitis B vaccines represents a major contribution to preventive health care of this century. Current and expanding worldwide application of hepatitis B vaccine promises to eliminate and eventually eradicate hepatitis B infection from the human population and, with it, many cases of cirrhosis and cancer of the liver.
authors.affiliation: Merck Vaccine Division, Merck & Co Inc, Whitehouse Station, NJ 08889-0100, USA.
authors.forename: R G
authors.initials: RG
authors.lastname: Douglas
mesh_terms: D006509:Hepatitis B / Q000517:prevention & control; D006514:Hepatitis B Surface Antigens / Q000276:immunology; D017325:Hepatitis B Vaccines; D006515:Hepatitis B virus / Q000276:immunology*; D006801:Humans; D014611:Vaccination / Q000639:trends; D015164:Vaccines, Inactivated; D014614:Vaccines, Synthetic
chemical_list: D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines; D015164:Vaccines, Inactivated; D014614:Vaccines, Synthetic