[A comparative evaluation of the content of T-lymphocyte subpopulations, alpha 1-thymosin and autoantibodies to epithelial thymic cells in the personnel in the 30-kilometer control zone of the accident at the Chernobyl Atomic Electric Power Station].
A significant decrease in mean number of CD5+, CD8(+)-lymphocytes in persons, who worked in 30-km zone of Chernobyl nuclear power station was revealed. A significant increase in percent of CD5+, CD4(+)-cell percents was observed in workers, who worked for 1,2-2,5 years in zone, but absolute number, were decreased comparing a control and data received in people, who have just arrived to work in 30-km zone. The positive correlation exists between the percent of lymphocytes and years of service in 30-km zone. The lower level of alpha 1-thymosine was revealed in serum of the persons, who worked in zone for 4.5-5 years than data received in people, who worked for 0.5 year. Increase level of serum autoantibodies reacting with thymic epithelial cell was detected in men, who worked in zone for 3-3.5 years. In persons, who worked more 5 years and have just arrived in zone identical data were received.
Titova
L D
LD
Oradovskaia
I V
IV
Sharova
N I
NI
Iarilin
A A
AA
D000328:Adult; D001323:Autoantibodies / Q000097:blood / Q000528:radiation effects*; D004848:Epithelium / Q000276:immunology / Q000528:radiation effects; D006801:Humans; D007111:Immunity, Cellular / Q000528:radiation effects; D018655:Lymphocyte Count / Q000528:radiation effects; D008875:Middle Aged; D011210:Power Plants; D018788:Radioactive Hazard Release; D016176:T-Lymphocyte Subsets / Q000528:radiation effects*; D000077596:Thymalfasin; D013947:Thymosin / Q000031:analogs & derivatives* / Q000097:blood / Q000528:radiation effects; D013950:Thymus Gland / Q000276:immunology* / Q000528:radiation effects*; D013997:Time Factors; D014455:Ukraine
D001323:Autoantibodies; D013947:Thymosin; D000077596:Thymalfasin