title: Fibromuscular dysplasia in intramuscular arteries of Japanese quail (Coturnix coturnix japonica).
abstract: Fibromuscular dysplasia (FMD) was found in the intramuscular arteries of both commercial (normal) and mutant (LWC) strains of Japanese quail. The mutant strain LWC is afflicted with an inherited muscular dystrophy exhibiting myotonia. The arterial lesions were classified as medial fibroplasia or medial hyperplasia, both being subtypes of medial FMD. Some lesions showed extensive proliferation of medial smooth muscle into the vascular lumen, resulting in partial occlusion of the affected blood vessel. FMD occurred more frequently in the mutant LWC quail than in the commercial strain. Ischaemic changes were absent in the associated muscle structures in both strains. The significance of FMD in relation to the skeletal muscle changes in the mutant LWC strain remains unclear.
authors.affiliation: Laboratory of Comparative Pathology, Hokkaido University, Sapporo, Japan.
authors.forename: I S
authors.initials: IS
authors.lastname: Braga
authors.forename: S
authors.initials: S
authors.lastname: Tanaka
authors.forename: C
authors.initials: C
authors.lastname: Itakura
authors.forename: M
authors.initials: M
authors.lastname: Mizutani
mesh_terms: D000818:Animals; D001158:Arteries / Q000473:pathology*; D003370:Coturnix; D004549:Elastin / Q000032:analysis; D005352:Fibromuscular Dysplasia / Q000473:pathology* / Q000503:physiopathology / Q000662:veterinary*; D018482:Muscle, Skeletal / Q000098:blood supply*; D009154:Mutation; D009207:Myoclonus / Q000235:genetics
chemical_list: D004549:Elastin