Specific effects of polyunsaturated fatty acids on gene expression.
Dietary polyunsaturated fatty acids modulate the transcription of numerous proteins including several hepatic lipogenic enzymes. Several lines of evidence indicate that polyunsaturated fatty acids do not regulate the transcription of hepatic lipogenic genes via a peroxisomal proliferator-activated receptor, but the mechanism may involve transcription factors related to the carbohydrate response region.
Baillie
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Department of Human Ecology, University of Texas, Austin 78712, USA.
Jump
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Clarke
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D000818:Animals; D004042:Dietary Fats, Unsaturated / Q000378:metabolism* / Q000494:pharmacology; D005231:Fatty Acids, Unsaturated / Q000378:metabolism* / Q000494:pharmacology; D005786:Gene Expression Regulation / Q000187:drug effects; D014157:Transcription Factors / Q000096:biosynthesis / Q000235:genetics; D014158:Transcription, Genetic
D004042:Dietary Fats, Unsaturated; D005231:Fatty Acids, Unsaturated; D014157:Transcription Factors