title: [Efficacy and tolerability of paroxetine in the treatment of the depressive phase of bipolar disorders].
abstract: Eighty patients aged between 20-65 years and suffering from bipolar disease according to DSM IV criteria, were treated with paroxetine for os at the single dosage of 20-40 mg/die. At regular intervals psychometric reagents were administered for the evaluation and the variations in the bipolar disease. Tolerability was excellent and side-effects mild, with a tendency to regress after the second week of therapy. The clinical assessment and the psychometric findings both suggest that paroxetina has a useful action on the bipolar disease.
authors.affiliation: Divisione di Psichiatria, Ospedali Riuniti, Cosenza.
authors.forename: L A
authors.initials: LA
authors.lastname: Ambrosio
authors.forename: D
authors.initials: D
authors.lastname: Buccomino
authors.forename: A
authors.initials: A
authors.lastname: Filippo
authors.forename: A
authors.initials: A
authors.lastname: Morelli
authors.forename: R
authors.initials: R
authors.lastname: Musacchio
authors.forename: F
authors.initials: F
authors.lastname: Pupo
authors.forename: F E
authors.initials: FE
authors.lastname: Romano
authors.forename: G
authors.initials: G
authors.lastname: Marchese
authors.forename: E
authors.initials: E
authors.lastname: Barrese
mesh_terms: D000328:Adult; D000368:Aged; D000928:Antidepressive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001714:Bipolar Disorder / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017374:Paroxetine / Q000008:administration & dosage / Q000627:therapeutic use*; D011569:Psychiatric Status Rating Scales
chemical_list: D000928:Antidepressive Agents; D017374:Paroxetine