New views on synapse-glia interactions.
Although glial cells ensheath synapses throughout the nervous system, the functional consequences of this relationship are uncertain. Recent studies suggest that glial cells may promote the formation of synapses and help to maintain their function by providing nerve terminals with energy substrates and glutamate precursors.
Pfrieger
F W
FW
Department of Neurobiology, Stanford University School of Medicine, California 94305-5401, USA. pfrieger@leland,stanford.edu
Barres
B A
BA
D000818:Animals; D001921:Brain / Q000502:physiology / Q000648:ultrastructure; D018698:Glutamic Acid / Q000378:metabolism; D008322:Mammals; D008959:Models, Neurological; D009411:Nerve Endings / Q000502:physiology; D009457:Neuroglia / Q000502:physiology*; D018377:Neurotransmitter Agents / Q000502:physiology; D013569:Synapses / Q000502:physiology*
D018377:Neurotransmitter Agents; D018698:Glutamic Acid