title: Mononucleosis-like illness as a manifestation of carbamazepine-induced anticonvulsant hypersensitivity syndrome.
abstract: We describe a case of infectious mononucleosis-like as a manifestation of carbamazepine-induced anticonvulsant hypersensitivity syndrome. Patch testing to carbamazepine and phenytoin were positive and negative to phenobarbital. Our results suggest a cell mediated type of immune response in the pathogenesis of this syndrome. Patch testing may be helpful in the diagnosis of anticonvulsant hypersensitivity syndrome caused by carbamazepine.
authors.affiliation: Section of Allergy, Hospital Universitario Marqués de Valdecilla, Santander, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Maquiera
authors.forename: S
authors.initials: S
authors.lastname: Yañez
authors.forename: L
authors.initials: L
authors.lastname: Fernández
authors.forename: F
authors.initials: F
authors.lastname: Rodríguez
authors.forename: I
authors.initials: I
authors.lastname: Picáns
authors.forename: I
authors.initials: I
authors.lastname: Sánchez
authors.forename: J
authors.initials: J
authors.lastname: Jeréz
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D002220:Carbamazepine / Q000009:adverse effects* / Q000627:therapeutic use; D003429:Cross Reactions; D003937:Diagnosis, Differential; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000209:etiology; D004829:Epilepsy, Generalized / Q000150:complications / Q000188:drug therapy; D005260:Female; D006801:Humans; D007244:Infectious Mononucleosis / Q000175:diagnosis*; D010328:Patch Tests; D010634:Phenobarbital / Q000627:therapeutic use; D010672:Phenytoin
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine; D010672:Phenytoin; D010634:Phenobarbital