title: [Reconstructive and non-reconstructive procedures in the treatment of the threatened limb].
abstract: Limb threatening ischemia is an acute step in the chronic course of peripheral arterial obstructive disease that requires some form of intervention. The objective of this study is to prove that reconstructive surgery as well as non reconstructive approaches are associated with positive results. Ours is a retrospective analysis of a ten year experience in the treatment of limb threatening ischemia. In the period 1983-93, 139 patients under-went 164 procedures. 67% of patients were diabetics. Early in the observation period the therapeutic strategy was non reconstructive, the procedure of choice was sympathectomy. Later vascular reconstructions have been recognized as the procedures of choice. In the cases not amenable to reconstructive procedures according to our group criteria (absence of a tibial vessel in continuity with a patent pedal arch), we have employed procedures such as prostanoid infusion; thrombolysis and epidural spinal cord stimulation. Reconstructive procedures have been associated with a decrease in the number of major amputations. Alternative procedures, employed in patients not amenable to reconstruction have proven worthwhile in terms of limb salvage even if this trend is limited to a short period of observation.
authors.affiliation: Divisione di Chirurgia Generale Servizio di Anestesia e Rianimazione, USL 1, Massa Carrara.
authors.forename: M
authors.initials: M
authors.lastname: Falaschi
authors.forename: D
authors.initials: D
authors.lastname: Valentini
authors.forename: F
authors.initials: F
authors.lastname: Fazzini
authors.forename: L
authors.initials: L
authors.lastname: Pasquali
authors.forename: L
authors.initials: L
authors.lastname: Gia
authors.forename: M
authors.initials: M
authors.lastname: Sturlese
authors.forename: C
authors.initials: C
authors.lastname: Spinetti
authors.forename: C
authors.initials: C
authors.lastname: Rossi
mesh_terms: D001157:Arterial Occlusive Diseases / Q000601:surgery* / Q000628:therapy*; D001807:Blood Vessel Prosthesis; D048909:Diabetes Complications; D004599:Electric Stimulation Therapy; D006801:Humans; D007511:Ischemia / Q000601:surgery* / Q000628:therapy*; D007866:Leg / Q000098:blood supply*; D011138:Polytetrafluoroethylene; D011453:Prostaglandins / Q000008:administration & dosage; D012008:Recurrence; D012189:Retrospective Studies; D015912:Thrombolytic Therapy; D014680:Veins / Q000637:transplantation
chemical_list: D011453:Prostaglandins; D011138:Polytetrafluoroethylene