title: Outcome of admitted malaria cases by treatment at Manicaland Provincial Hospital, Zimbabwe.
abstract: OBJECTIVE
  To determine the outcome of admitted malaria cases according to age, late presentation, and antimalarial drug treatments received.
  
  
  METHODS
  We reviewed all March 1994 hospital and laboratory records of patients with a clinical diagnosis of malaria.
  
  
  METHODS
  Manicaland Provincial Hospital.
  
  
  METHODS
  319 clinical malaria cases.
  
  
  METHODS
  Cases were classified as uncomplicated, complicated and unconscious.
  
  
  RESULTS
  Of the 319 cases reviewed, 213 slide examinations were done and 174 (82pc) were slide positive. Of slide positive admissions, 91 (52pc) were complicated and 37 (21pc) were unconscious; 22 (13pc) died. Case fatality was two pc in uncomplicated cases, six pc in complicated cases, and 46pc in unconscious cases. Uncomplicated and complicated cases did as well on chloroquine (none of the 53 died) as on other treatments (four of the 76 died), whereas unconscious patients did poorly regardless of therapy received. Twelve patients received no therapy on their first hospital day and four died. There was no significant association between young age (age < 5 years) and complications or death, nor between late presentation (illness onset > or = 3 days before hospital presentation) and complications or death.
authors.affiliation: University of Zimbabwe Medical School, Department of Community Medicine, Harare, Zimbabwe.
authors.forename: A I
authors.initials: AI
authors.lastname: Mahomva
authors.forename: D E
authors.initials: DE
authors.lastname: Peterson
authors.forename: L
authors.initials: L
authors.lastname: Rakata
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000962:Antimalarials / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002738:Chloroquine / Q000627:therapeutic use; D005260:Female; D017052:Hospital Mortality; D006760:Hospitalization; D006801:Humans; D008288:Malaria / Q000150:complications / Q000188:drug therapy*; D008297:Male; D017063:Outcome Assessment, Health Care; D012189:Retrospective Studies; D015030:Zimbabwe
chemical_list: D000962:Antimalarials; D002738:Chloroquine