[Risk factors for depression after apoplexy].
An unselected cohort of 285 stroke patients, median age 69 years, was studied for correlation between potential risk factors and the one-year incidence of post-stroke depression (PSD). The following factors correlated significantly to PSD a history of previous stroke, a history of previous depression, female gender, living alone and social distress pre-stroke. Further, social inactivity, decrease in social activity, pathological crying and intellectual impairment at one month but not functional outcome correlated to PSD. A multivariate regression analysis showed that intellectual impairment explained 42% of the variance of the mood score. Major depression was unrelated to lesion location. We conclude the etiology of PSD is a complex mixture of pre-stroke personal and social factors and stroke-induced social, emotional and intellectual handicap.
Andersen
G
G
Neurologisk afdeling og neuroradiologisk afdeling, Aalborg Sygehus.
Vestergaard
K
K
Ingeman-Nielsen
M W
MW
Lauritzen
L U
LU
D000328:Adult; D000368:Aged; D002561:Cerebrovascular Disorders / Q000150:complications* / Q000523:psychology; D015331:Cohort Studies; D003863:Depression / Q000175:diagnosis / Q000209:etiology*; D004644:Emotions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors; D012934:Social Isolation