Oligomenorrhea treatment by purified FSH using a fixed protocol.
This study is designed to evaluate the effectiveness, safety and tolerability of a low dose of purified FSH administration using a fixed protocol in oligomenorrheic patients not desiring pregnancy. We used a low dose (75 IU/day for 5 days) of purified FSH (Metrodin) in 10 oligomenorrheic patients (aged 18-30) for 25 cycles. The onset of menstruation occurred in 7 patients (70%) and in 19 treatment cycles (76%), the ovulation was verified in 5 of these patients (50%) for 13 cycles (52%). One patient had spotting after the treatment, 2 patients did not have any response. The treatment did not cause side effects and it showed a good tolerability.
Dessole
S
S
Institute of Obstetrics and Gynecology, University of Sassari, Italy.
Coccollone
E
E
Ambrosini
G
G
D'Antona
D
D
Vargiu
N
N
Cherchi
P L
PL
D000328:Adult; D004334:Drug Administration Schedule; D005260:Female; D005640:Follicle Stimulating Hormone / Q000627:therapeutic use*; D006728:Hormones / Q000097:blood; D006801:Humans; D009839:Oligomenorrhea / Q000097:blood / Q000188:drug therapy*; D016896:Treatment Outcome
D006728:Hormones; D005640:Follicle Stimulating Hormone