[Gram-positive, catalase negative cocci isolated from clinical material--identification and drug sensitivity of strains].
4608 clinical specimens (including 1641 samples of blood) for bacteriological examination were obtained from patients hospitalized in different wards of National Clinical Hospital No 1 in Warsaw. Strains were cultured, identified and their sensitivity to antibacterial drugs was determined during 14 months with the use of semi-automated API (ATB-plus) system (bioMérieux, France). Strains of Gram-positive, catalase-negative cocci were separated from all cultured strains. They belonged to the genera: Streptococcus, Enterococcus, Gemella, Aerococcus and Lactococcus (538 strains altogether). 238 Streptococcus spp. strains (44.2%) and 201 Enterococcus spp. strains (37.4%)were isolated from all specimens. The greatest number of catalase-negative cocci was obtained from wound smears -420 strains, which amounts to 78.2% of all strains. Among isolates dominated E. faecalis strains -104 (19.3%) and E. faecium strains - 70 (13.0% of all isolated strains). Vancomycin was the most effective antibacterial drug against gram-positive, catalase-negative cocci isolated from patients hospitalized in our hospital. Vancomycin-resistant strains constituted from 3% to 18% of strains depending on a species.
Rokosz
A
A
Zakład Bakteriologii Klinicznej AM w Warszawie.
Rafałowska
K
K
Lipnicki
D
D
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001769:Blood / Q000382:microbiology*; D002374:Catalase / Q000378:metabolism; D004352:Drug Resistance, Microbial; D006095:Gram-Positive Cocci / Q000187:drug effects / Q000201:enzymology / Q000302:isolation & purification*; D006801:Humans; D008826:Microbial Sensitivity Tests; D013045:Species Specificity; D014640:Vancomycin / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D014640:Vancomycin; D002374:Catalase