title: Peptide transporters.
abstract: Proton-coupled peptide transporters found in animal cells are unique because of their energetics and their ability to accept a broad spectrum of chemically diverse peptides as substrates. The abundant expression of these transporters in the small intestine and the kidney indicates their importance in the maintenance of protein nutrition. There is also evidence for additional functions of the peptide transporters which are of physiological, pharmacological and clinical relevance.
authors.affiliation: Department of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta 30912-2100, USA.
authors.forename: V
authors.initials: V
authors.lastname: Ganapathy
authors.forename: F H
authors.initials: FH
authors.lastname: Leibach
mesh_terms: D000818:Animals; D001419:Bacteria / Q000378:metabolism; D002352:Carrier Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D000074011:Peptide Transporter 1; D010944:Plants / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D027981:Symporters; D014982:Xenopus laevis; D015003:Yeasts / Q000378:metabolism
chemical_list: D002352:Carrier Proteins; D000074011:Peptide Transporter 1; D012333:RNA, Messenger; C489940:Slc15a1 protein, rat; D027981:Symporters; C093694:hydrogen-coupled oligopeptide transporter PepT2