Heparinase-guided thrombelastography in an anticoagulated parturient.
We describe the use of heparinase-guided thrombelastography in the assessment of a parturient who had been anticoagulated with heparin for suspected thromboembolic disease. Reversal of the heparin effect in the heparinase-treated sample facilitated administration of protamine and successful subarachnoid analgesia for delivery.
Abramson
D C
DC
Department of Anesthesiology, University of Texas Medical School at Houston 77030, USA.
Abouleish
E I
EI
Pivalizza
E G
EG
Luehr
S L
SL
Myers
T
T
Phillips
M D
MD
D000328:Adult; D016362:Analgesia, Obstetrical / Q000379:methods; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006494:Heparin Antagonists / Q000494:pharmacology*; D019763:Heparin Lyase; D006801:Humans; D011133:Polysaccharide-Lyases / Q000494:pharmacology*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy*; D011479:Protamines / Q000494:pharmacology; D013916:Thrombelastography / Q000379:methods*; D013923:Thromboembolism / Q000188:drug therapy*
D006494:Heparin Antagonists; D011479:Protamines; D006493:Heparin; D011133:Polysaccharide-Lyases; D019763:Heparin Lyase