Multicentric reticulohistiocytosis.
We describe a 42-year-old man with a five-year history of arthritis mutilans-like destructive joint changes and with a one-year history of nodules on the fingers, ears, oral mucosa, pharynx, larynx, vocal cords, some being ulcerated and haemorrhagic. He was diagnosed as having rheumatoid arthritis; however, biopsies from the nodules on the oral mucosa and ear revealed multicentric reticulohistiocytosis. The large nodule over the olecranon process, simulating a rheumatoid nodule but diagnosed as multicentric reticulohistiocytosis with biopsy; ulcerated and haemorrhagic nodules on the oral mucosa; and rapidly progressive joint destructions make our case interesting.
Kocanaogullari
H
H
Department of Medicine, Division of Rheumatology, Ege University, School of Medicine, Izmir, Turkey.
Ozsan
H
H
Oksel
F
F
Ozturk
G
G
Kandiloglu
G
G
Ustun
E E
EE
Doganavsargil
E
E
D000328:Adult; D018501:Antirheumatic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000175:diagnosis* / Q000503:physiopathology; D001379:Azathioprine / Q000008:administration & dosage / Q000627:therapeutic use; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D015614:Histiocytosis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D008297:Male
D018501:Antirheumatic Agents; D001379:Azathioprine