title: The efficacy of ivermectin in treating rabbits experimentally infected with Eimeria as indicated parasitologically and histologically.
abstract: Ivermectin (Ivomec) was used as coccidiocidal drug against Eimeria in experimentally infected rabbits as indicated parasitologically & histologically. Twenty Bosskat rabbits, were divided in to 5 groups, 3 groups were inoculated with 1000 sporulated oocysts and the other 2 groups were kept as negative controls with and without Ivermectin administration. Ivermectin (1:10) was injected subcutaneously in a dose of 0.5 ml in animals of groups 1,2 & 3. The treatment of group (1) was on the 4th day A.I. and on the 4th day and 7th day A.I.in group (2). The treated animals with one or two doses showed mild coccidiosis with very few number of oocysts deposition & rapid intestinal regeneration with degenerated Eimeria developmental stages, especially the asexual ones.
authors.affiliation: Department of Parasitology, Faculty of Medicine, Ain Shams University, Abbassia, Cairo, Egypt.
authors.forename: M A
authors.initials: MA
authors.lastname: Arafa
authors.forename: M Q
authors.initials: MQ
authors.lastname: Wanas
mesh_terms: D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use*; D003048:Coccidiosis / Q000188:drug therapy / Q000662:veterinary*; D004539:Eimeria; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy / Q000662:veterinary*; D007421:Intestine, Small / Q000469:parasitology / Q000473:pathology; D007559:Ivermectin / Q000627:therapeutic use*; D008297:Male; D011817:Rabbits / Q000469:parasitology*
chemical_list: D000981:Antiprotozoal Agents; D007559:Ivermectin