title: The use of mannitol in severe head injury. Brain Trauma Foundation.
abstract: Mannitol is effective in reducing ICP, and we recommend its use in the management of traumatic intracranial hypertension. Serum osmolalities greater than 320 mOSsm/L and hypovolemia should be avoided. Some data suggest that bolus administration is preferable to continuous infusion.
mesh_terms: D000818:Animals; D001930:Brain Injuries / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D006259:Craniocerebral Trauma / Q000150:complications / Q000503:physiopathology / Q000628:therapy*; D004234:Diuretics, Osmotic / Q000627:therapeutic use*; D004285:Dogs; D004630:Emergencies; D006801:Humans; D007427:Intracranial Pressure; D016239:MEDLINE; D008353:Mannitol / Q000627:therapeutic use*; D011559:Pseudotumor Cerebri / Q000209:etiology / Q000517:prevention & control*
chemical_list: D004234:Diuretics, Osmotic; D008353:Mannitol