title: Modulation of protein structure and function by asparagine-linked glycosylation.
abstract: In eukaryotic cells, many enzymes are devoted to the construction of the complex glycan structures that decorate secreted and cell-surface proteins. Recent studies have begun to elucidate the effects of asparagine-linked glycosylation on protein folding and on the structure and function of mature glycoproteins.
authors.affiliation: Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
authors.forename: S E
authors.initials: SE
authors.lastname: O'Connor
authors.forename: B
authors.initials: B
authors.lastname: Imperiali
mesh_terms: D001216:Asparagine / Q000737:chemistry*; D006020:Glycopeptides / Q000737:chemistry / Q000378:metabolism; D006023:Glycoproteins / Q000737:chemistry* / Q000378:metabolism; D006031:Glycosylation; D017510:Protein Folding; D017433:Protein Structure, Secondary; D013329:Structure-Activity Relationship
chemical_list: D006020:Glycopeptides; D006023:Glycoproteins; D001216:Asparagine