title: Propofol for sedation in a mentally retarded dental patient.
abstract: A 21-yr-old mentally retarded and cardiovascularly compromised woman who required dental restorative work and extractions was admitted to our clinic. We had previously successfully sedated her with propofol and midazolam. In this case she was sedated with a 1% propofol solution administered initially at a rate of 8 mg/kg-hr. After 5 min, the infusion rate was lowered to 5 mg/kg-hr, and after the local anesthetic injection, was adjusted to 3 mg/kg-hr. After 15 min, the patient became restless, and the propofol infusion rate was again increased to 5 mg/kg-hr. The patient's airway was well maintained during the entire procedure; she remained well sedated, and no adverse effects were experienced.
authors.affiliation: Division of Maxillo-facial Anesthesia, University of Stellenbosch, Tygerberg, South Africa.
authors.forename: J A
authors.initials: JA
authors.lastname: Roelofse
authors.forename: P
authors.initials: P
authors.lastname: van der Bijl
mesh_terms: D000328:Adult; D000766:Anesthesia, Dental / Q000379:methods*; D018686:Anesthetics, Intravenous / Q000008:administration & dosage; D003730:Dental Care for Persons with Disabilities; D003793:Dental Restoration, Permanent; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D008607:Intellectual Disability / Q000150:complications; D015742:Propofol / Q000008:administration & dosage*; D014081:Tooth Extraction
chemical_list: D018686:Anesthetics, Intravenous; D006993:Hypnotics and Sedatives; D015742:Propofol