title: The effect of salinomycin and lasalocid on laboratory cultures of Enterococcus faecium and Staphylococcus gallinarum strains.
abstract: The growth of Enterococcus faecium strains CCM 4231 and EF 26, and Staphylococcus gallinarum SG 31 was inhibited by salinomycin and lasalocid at concentrations of 25 and 50 mg/L. Staphylococcus gallinarum was more sensitive to the additives used than were enterococci. Maximum inhibition (90%) was measured after the growth with the SG 31 strain in the presence of both ionophores. Growth of organisms was more inhibited by salinomycin at 25 mg/L (67.5%) than at 50 mg/L (63%). The inhibitory effect in enterococcal strains reached after the addition of salinomycin and lasalocid (on average) 63 and 58%, respectively. The CCM 4231 strain was more inhibited by salinomycin as well as by lasalocid than was the EF 26 strain.
authors.affiliation: Institute of Animal Physiology, Slovak Academy of Sciences, Kosice, Slovakia.
authors.forename: A
authors.initials: A
authors.lastname: Lauková
authors.forename: M
authors.initials: M
authors.lastname: Baran
authors.forename: G I
authors.initials: GI
authors.lastname: Kalacnjuk
mesh_terms: D016984:Enterococcus faecium / Q000187:drug effects* / Q000254:growth & development; D007476:Ionophores / Q000494:pharmacology*; D007832:Lasalocid / Q000494:pharmacology*; D011714:Pyrans / Q000494:pharmacology*; D013210:Staphylococcus / Q000187:drug effects* / Q000254:growth & development; D000095662:Polyether Polyketides
chemical_list: D007476:Ionophores; D007832:Lasalocid; D011714:Pyrans; C010327:salinomycin; D000095662:Polyether Polyketides