title: Hypothenar hammer syndrome successfully managed with intravenous prostaglandin E1 and heparin and with correction of the thrombogenic risk profile. A case report.
abstract: A fifty-one-year-old man presented with a history, symptoms, and clinical findings typical of a hypothenar hammer syndrome in his dominant hand. A thrombotic obstruction in the distal section of the ulnar artery with multiple downstream occlusions of proper digital arteries were documented angiographically. Coexistence of additional cardiovascular risk factors (smoking-induced polycythemia, obesity, hypercholesterolemia, and hypertension) was identified. Conservative management with intravenous heparin and prostaglandin E1 together with measures directed at controlling the additional risk factors (repeated venesection, immediate smoking cessation, and low-lipid diet) resulted in a striking clinical and angiographic improvement of the digital perfusion, without resort to interventional measures or thrombolysis.
authors.affiliation: Department of Angiology, Medical School of Hannover, Germany.
authors.forename: I
authors.initials: I
authors.lastname: Wieczorek
authors.forename: A
authors.initials: A
authors.lastname: Farber
authors.forename: K
authors.initials: K
authors.lastname: Alexander
mesh_terms: D000527:Alprostadil / Q000627:therapeutic use*; D000925:Anticoagulants / Q000627:therapeutic use*; D005385:Fingers / Q000098:blood supply* / Q000000981:diagnostic imaging; D006493:Heparin / Q000627:therapeutic use*; D006801:Humans; D007511:Ischemia / Q000000981:diagnostic imaging / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012307:Risk Factors; D013577:Syndrome; D013923:Thromboembolism / Q000150:complications / Q000188:drug therapy; D017535:Ulnar Artery
chemical_list: D000925:Anticoagulants; D006493:Heparin; D000527:Alprostadil