Study of oestrogen and progesterone receptors in meningiomas by a technique utilizing the binding hormones in a polymerized state.
Forty six cases of meningiomas were studied by utilizing oestrogen and progesterone hormone bound to fluroscent-iso-thiocynate (FITC) for the presence of oestrogen and progesterone receptors. Oestrogen receptors were present in 33% cases and only one fourth of these showed strong positivity. Progesterone receptors were positive in 41% cases, and more than half of these showed strong positivity. Thus this study revealed higher positivity rate for progesterone receptors than oestrogen receptors.
Kumar
S
S
Department of Neurosurgery, G.B. Pant Hospital, New Delhi.
Mandal
A K
AK
Mandal
A
A
Puri
V
V
Aggarwal
S P
SP
Mehndiratta
M
M
D000293:Adolescent; D000328:Adult; D005260:Female; D016650:Fluorescein-5-isothiocyanate; D005456:Fluorescent Dyes; D006801:Humans; D008297:Male; D008577:Meningeal Neoplasms / Q000378:metabolism*; D008579:Meningioma / Q000378:metabolism*; D008875:Middle Aged; D011960:Receptors, Estrogen / Q000378:metabolism*; D011980:Receptors, Progesterone / Q000378:metabolism*
D005456:Fluorescent Dyes; D011960:Receptors, Estrogen; D011980:Receptors, Progesterone; D016650:Fluorescein-5-isothiocyanate