title: Primary resection and synchronous regional hepatic chemotherapy or cryotherapy for colorectal cancer with liver metastases.
abstract: Twenty-two patients with colorectal cancer and synchronous unresectable hepatic metastases were treated by resection the primary tumour with concurrent insertion of an Infusaid infusaport system for regional chemoperfusion (hepatic arterial 20, portal venous 2). Four patients in addition had cryotherapy the liver metastases. Morbidity from the synchronous procedures was minimal. Median survival was 10 months. Four patients with poorly-differentiated tumours had a poor response, with a median survival of 3.75 months.
authors.affiliation: Department of Surgery, The St. George Hospital, Kogarah, Sydney, Australia.
authors.forename: V
authors.initials: V
authors.lastname: Dasappa
authors.forename: W B
authors.initials: WB
authors.lastname: Ross
authors.forename: J
authors.initials: J
authors.lastname: King
authors.forename: D W
authors.initials: DW
authors.lastname: King
authors.forename: P R
authors.initials: PR
authors.lastname: Clingan
authors.forename: D L
authors.initials: DL
authors.lastname: Morris
mesh_terms: D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage*; D015179:Colorectal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D003131:Combined Modality Therapy; D003452:Cryosurgery; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage*; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000556:secondary* / Q000601:surgery; D015996:Survival Rate
chemical_list: D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil