Controlling growth of the wing: vestigial integrates signals from the compartment boundaries.
In the past few years it has become apparent that the anterior/posterior (A/P) and dorsal/ventral (D/V) compartment boundaries serve as the source of long-range signals that organize the A/P and D/V axes of the Drosophila wing. Recent work suggests that the vestigial gene may function as a nodal point through which the growth-controlling activity of these two patterning systems is integrated.
Cohen
S M
SM
European Molecular, Biology Laboratory, Heidelberg, Germany. scohen@embl-heidelberg.de
D000818:Animals; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000254:growth & development*; D018507:Gene Expression Regulation, Developmental; D009687:Nuclear Proteins / Q000502:physiology*; D015398:Signal Transduction; D014921:Wings, Animal / Q000254:growth & development*
D029721:Drosophila Proteins; D009687:Nuclear Proteins; C095064:vg protein, Drosophila