Sleep and degenerative neurologic disorders.
This article summarizes sleep disturbances in a variety of neuro-degenerative diseases, including Parkinson's disease, multiple system atrophy, and amyotrophic lateral sclerosis. Sleep complaints in these conditions include insomnia, hypersomnia, abnormal motor activity and behavior during sleep, sleep-related breathing problems, and circadian rhythm sleep disturbances. Clinical examination followed in selected cases by polysomnographic, multiple sleep latency, and other laboratory tests is essential for correct diagnosis and treatment of these sleep disturbances.
Chokroverty
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Department of Neurology, St. Vincent's Hospital and Medical Center, New York, New York, USA.
D000368:Aged; D000544:Alzheimer Disease / Q000503:physiopathology; D002526:Cerebellar Diseases / Q000503:physiopathology; D004422:Dystonia Musculorum Deformans / Q000503:physiopathology; D006801:Humans; D006816:Huntington Disease / Q000503:physiopathology; D016472:Motor Neuron Disease / Q000503:physiopathology; D009422:Nervous System Diseases / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D010300:Parkinson Disease / Q000503:physiopathology; D012791:Shy-Drager Syndrome / Q000503:physiopathology; D012890:Sleep / Q000502:physiology*; D012893:Sleep Wake Disorders / Q000503:physiopathology / Q000628:therapy; D013494:Supranuclear Palsy, Progressive / Q000503:physiopathology; D005879:Tourette Syndrome / Q000503:physiopathology