title: [Characteristics of the course of bronchial asthma in patients with associated diseases of the upper respiratory tract].
abstract: The examination of 56 patients (35 females and 21 males) with bronchial asthma (BA) associated with nasal and paranasal diseases revealed allergic rhinosinusopathy (ARSP) in 87.5% of the examinees. Nasal and paranasal affections in BA of bacterial and atopic genesis differed. The study of external respiration showed that its volume and rate abnormality increased with growing severity of nasal and paranasal affections. The results of cytological investigations of impression smears of the nasal mucosa, sputum and bronchial lavage (portion I and II) suggest that elevated levels of eosinophilic leukocytes in all the studied specimens in BA patients with ARSP may evidence for common character of allergic reactions in the above nasal and bronchial diseases.
authors.forename: V I
authors.initials: VI
authors.lastname: Makolkin
authors.forename: N V
authors.initials: NV
authors.lastname: Chichkova
authors.forename: S I
authors.initials: SI
authors.lastname: Ovcharenko
mesh_terms: D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D018893:Bronchoalveolar Lavage; D001999:Bronchoscopy; D004804:Eosinophils / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000276:immunology; D010038:Otorhinolaryngologic Diseases / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D012119:Respiration; D012221:Rhinitis, Allergic, Perennial / Q000150:complications / Q000175:diagnosis / Q000276:immunology; D012852:Sinusitis / Q000150:complications / Q000175:diagnosis / Q000276:immunology; D013183:Sputum / Q000276:immunology