Makaluvic acids A and B: novel alkaloids from the marine sponge Zyzzya fuliginosus.
Two new substituted pyrrolecarboxylic acids, makaluvic acids A (5) and B (6), were isolated from the sponge Zyzzya fuliginosus, which was collected in Chuuk Atoll, Federated States of Micronesia. The known alkaloids 3,7-dimethylisoguanine (1) and makaluvamines A (2), E (3), and K (4) were also isolated.
Fu
X
X
Department of Chemistry, University of Oklahoma, Norman 73019, USA.
Ng
P L
PL
Schmitz
F J
FJ
Hossain
M B
MB
van der Helm
D
D
Kelly-Borges
M
M
D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification* / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D018360:Crystallography, X-Ray; D004354:Drug Screening Assays, Antitumor; D007941:Leukemia P388 / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D011161:Porifera / Q000737:chemistry*; D011758:Pyrroles / Q000302:isolation & purification* / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000970:Antineoplastic Agents; D011758:Pyrroles; C103460:makaluvic acid A; C103461:makaluvic acid B