Evolution of sonographic findings in a fetus with agenesis of the urethra, vagina, and rectum.
In a 12-week gestation fetus, routine ultrasound examination suggested dilated loops of bowel. Repeat scans at 13 and 15 weeks showed normal growth but persistence of bowel dilatation. At 20 weeks there was megacystis, hyperechogenic bowel, ascites, and oligohydramnios. The diagnosis of cloacal abnormality was suspected and the parents chose to have pregnancy termination. Post-mortem examination demonstrated female pseudohermaphroditism with agenesis of the urethra, vagina, and rectum.
Carroll
S G
SG
Harris Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, London, U.K.
Hyett
J
J
Eustace
D
D
Seller
M J
MJ
Nicolaides
K H
KH
D000293:Adolescent; D012734:Disorders of Sex Development; D005260:Female; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D012007:Rectum / Q000002:abnormalities* / Q000000981:diagnostic imaging; D016216:Ultrasonography, Prenatal; D014521:Urethra / Q000002:abnormalities* / Q000000981:diagnostic imaging; D014621:Vagina / Q000002:abnormalities* / Q000000981:diagnostic imaging