title: The accuracy of magnetic resonance phase velocity measurements in stenotic flow.
abstract: Nuclear magnetic resonance (MR) can be used to measure velocities in fluid flow using the technique of phase velocity mapping. Advantages of MR velocimetry include the simultaneous mapping of the entire flow field through a non-contacting, magnetic window. The phase velocity mapping technique assumes that velocity is constant over the measurement time (typically around 10 ms). For many fluid flows, this assumption is not valid. The current study showed that MR phase velocity measurements of velocity through stenotic flow can be in error by over 100% immediately upstream and downstream of the stenosis throat and by 20% far downstream of the throat in comparison with laser Doppler anemometer measurements taken at the same location. Highly turbulent flow also led to significant errors in velocity measurement. These errors can be attributed to several sources including low signal-to-noise ratio, additional phase shifts due to non-constant velocities, and non-stationary transit-time effects. Velocity measurement errors could be reduced to under 30% at all measurement locations through the use of MR sequences with high signal-to-noise ratios, low echo times, and thick slices.
authors.affiliation: George W. Woodruff School of Mechanical Engineering Georgia Institute of Technology Atlanta 30332-0405, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Siegel
authors.forename: J N
authors.initials: JN
authors.lastname: Oshinski
authors.forename: R I
authors.initials: RI
authors.lastname: Pettigrew
authors.forename: D N
authors.initials: DN
authors.lastname: Ku
mesh_terms: D001157:Arterial Occlusive Diseases / Q000175:diagnosis / Q000503:physiopathology*; D016477:Artifacts; D001783:Blood Flow Velocity; D005583:Fourier Analysis; D018056:Hemorheology; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D017078:Laser-Doppler Flowmetry; D009682:Magnetic Resonance Spectroscopy; D012815:Signal Processing, Computer-Assisted