title: [Hepatitis E in a nonendemic region: antibodies to hepatitis E virus in various groups of residents].
abstract: Increase in the number of seropositive subjects in the population of European and North-American regions not endemic for hepatitis E stimulated research in this field. This study was aimed at investigating the incidence of IgG antibodies to hepatitis E virus (anti-HEV-IgG) in subjects with different liver diseases and in groups at increased risk of infection in a nonendemic region. In patients with different diseases of the liver the incidence of anti-HEV-IgG varied from 5.1 to 14.3%, in medical workers and former blood donors not allowed to donate blood because of increased transaminase levels in the blood 5.1 and 5.3%, respectively. In the reference group this level was appreciably lower-only 1.8%, this being rather close to the incidence of anti-HEV-IgG in the population of a nonendemic region (2.1%). There were no seropositive women in the group of healthy pregnant women in a non-endemic region, whereas in an endemic region (in Kyrghyzstan) 15% of pregnant women were seropositive for anti-HEV.
authors.forename: O E
authors.initials: OE
authors.lastname: Fedorova
authors.forename: M S
authors.initials: MS
authors.lastname: Balaian
authors.forename: M I
authors.initials: MI
authors.lastname: Mikhaĭlov
authors.forename: I P
authors.initials: IP
authors.lastname: Pavlova
authors.forename: O A
authors.initials: OA
authors.lastname: Slasten
authors.forename: Iu I
authors.initials: IuI
authors.lastname: Patiutko
authors.forename: I V
authors.initials: IV
authors.lastname: Sagaĭdak
authors.forename: R K
authors.initials: RK
authors.lastname: Usmanov
mesh_terms: D001782:Blood Donors; D005260:Female; D006282:Health Personnel; D006508:Hepatitis Antibodies / Q000097:blood*; D016751:Hepatitis E / Q000453:epidemiology*; D016752:Hepatitis E virus / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D015994:Incidence; D011247:Pregnancy; D012307:Risk Factors; D012426:Russia / Q000453:epidemiology
chemical_list: D006508:Hepatitis Antibodies; D007074:Immunoglobulin G