Stenting of aortopulmonary collaterals in complex pulmonary atresia.
BACKGROUND
The optimal treatment of patients with complex pulmonary atresia remains controversial. Surgical unifocalization programs are increasing popular but have not previously or currently gained universal acceptance. Furthermore, not all patients are suitable for attempts at biventricular correction. These patients may become increasingly symptomatic and require palliation.


RESULTS
We attempted to palliate 12 patients with progressive symptomatic hypoxemia. Each had at least one stenotic but balloon-dilatable collateral supplying at least three lung segments. It was impossible to traverse the stenotic area with the stent in 1 patient, despite two attempts. Twelve stents were thus deployed in 11 patients. There was no effect in 1 patient who had multiple stenoses distal to the stented area. There was excellent palliation in the remainder, arterial oxygen saturation 45% to 79% before stenting (mean, 64 +/- 12%) rising to 67% to 90% (mean, 78 +/- 10%, P < .01) at discharge from hospital. One patient was referred for surgery to secure blood flow to a nearly totally occluded side branch to the right upper lobe traversed by the stent. There was an excellent symptomatic response in the remainder, with an early increase in exercise duration (P < .01). Late arterial desaturation occurred in 2 patients. In 1, there was pulmonary arterial hypertension in the lung segments supplied by the stented vessel. A stenosis had developed within the stent in the other patient, who was noncompliant with anticoagulation therapy.


CONCLUSIONS
Stenting of stenotic aortopulmonary collaterals can achieve excellent palliation in the majority of this highly selected subgroup of patients with complex pulmonary atresia.
Redington
A N
AN
Department of Pediatric Cardiology, Royal Brompton Hospital, London, England.
Somerville
J
J
D000293:Adolescent; D000328:Adult; D015901:Angiography, Digital Subtraction; D001011:Aorta / Q000503:physiopathology*; D001027:Aortography; D002648:Child; D002675:Child, Preschool; D003097:Collateral Circulation; D005500:Follow-Up Studies; D006801:Humans; D000860:Hypoxia / Q000628:therapy; D018633:Pulmonary Atresia / Q000503:physiopathology* / Q000628:therapy*; D011652:Pulmonary Circulation; D015607:Stents / Q000009:adverse effects