title: Negative pressure pulmonary edema as a post-anesthetic complication associated with upper airway obstruction in a horse.
abstract: An 8-year-old Trakehner mare developed fulminant pulmonary edema following suspected upper airway obstruction 50 minutes into an otherwise unremarkable anesthetic recovery after surgery for left cricoarytenoideus dorsalis muscle reinnervation and ventriculocordectomy. Establishing a patent airway by orotracheal reintubation and cardiopulmonary resuscitation attempts were unsuccessful. Gross, histological, and electron microscopic postmortem examination showed severe hemorrhagic pulmonary edema. Laryngeal swelling or hemorrhage were not evident, suggesting laryngospasm or functional airway collapse associated with the underlying left laryngeal paralysis, as a cause of the upper airway obstruction. Negative pressure pulmonary edema is rarely reported in the veterinary literature as a postanesthetic complication.
authors.affiliation: Department of Clinical Sciences, Cornell University College of Veterinary Medicine, Ithaca, NY 14853, USA.
authors.forename: A S
authors.initials: AS
authors.lastname: Tute
authors.forename: P A
authors.initials: PA
authors.lastname: Wilkins
authors.forename: R D
authors.initials: RD
authors.lastname: Gleed
authors.forename: K M
authors.initials: KM
authors.lastname: Credille
authors.forename: D J
authors.initials: DJ
authors.lastname: Murphy
authors.forename: N G
authors.initials: NG
authors.lastname: Ducharme
mesh_terms: D000402:Airway Obstruction / Q000150:complications / Q000503:physiopathology / Q000662:veterinary*; D000762:Anesthesia Recovery Period; D000818:Animals; D005260:Female; D006734:Horse Diseases / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology*; D006736:Horses / Q000502:physiology*; D008168:Lung / Q000473:pathology / Q000503:physiopathology / Q000648:ultrastructure; D008854:Microscopy, Electron / Q000662:veterinary; D011175:Positive-Pressure Respiration; D011654:Pulmonary Edema / Q000209:etiology / Q000503:physiopathology / Q000662:veterinary*