title: Infertile women with and without endometriosis: a case control study of luteal phase and other infertility conditions.
abstract: OBJECTIVE
  To assess the relationship in infertile women between endometriosis and luteal phase defects and other infertility conditions.
  
  
  METHODS
  University Medical School.
  
  
  METHODS
  Case-control study.
  
  
  METHODS
  One hundred and seventy-four infertile women with endometriosis and 174 infertile women without endometriosis, all of them studied by laparoscopy. The inclusion criteria were failure of six cycles of ovulation stimulation or abnormal preliminary study (abnormal pelvic physical, hysterosalpingographic or ultrasound findings).
  
  
  RESULTS
  The frequency of out-of-phase biopsies (16.1% vs 16.7%) as well as other endometrial abnormalities were similar in endometriosis associated infertility (EAI) and in non-endometriosis infertility (NEI). Mean progesterone and prolactin levels, as well as the proportion of abnormal progesterone levels (37.4% vs 44.3%) and of hyperprolactinemia (12.9% vs 13.2%) were similar in EAI and NEI. The frequency of uterine myomas was similar in both groups. Sperm characteristics were not better in EAI than in NEI. Higher endometriosis stages were not associated with a higher frequency of the aforementioned conditions.
  
  
  CONCLUSIONS
  Luteal phase defects, sperm abnormalities and myomas are no more common in EAI than in NEI or in advanced stages of endometriosis.
authors.affiliation: Department of Obstetrics and Gynecology, Hospital of Cruces, Baracaldo, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Matorras
authors.forename: F
authors.initials: F
authors.lastname: Rodríguez
authors.forename: C
authors.initials: C
authors.lastname: Pérez
authors.forename: J I
authors.initials: JI
authors.lastname: Pijoan
authors.forename: J L
authors.initials: JL
authors.lastname: Neyro
authors.forename: F J
authors.initials: FJ
authors.lastname: Rodríguez-Escudero
mesh_terms: D000328:Adult; D001706:Biopsy; D016022:Case-Control Studies; D004715:Endometriosis / Q000150:complications* / Q000453:epidemiology; D004717:Endometrium / Q000473:pathology; D005260:Female; D006801:Humans; D006966:Hyperprolactinemia / Q000150:complications / Q000453:epidemiology; D015994:Incidence; D007247:Infertility, Female / Q000453:epidemiology / Q000209:etiology*; D010535:Laparoscopy; D007889:Leiomyoma / Q000150:complications / Q000453:epidemiology; D008183:Luteal Phase / Q000502:physiology*; D008297:Male; D011374:Progesterone / Q000097:blood; D013076:Sperm Count; D013081:Sperm Motility; D013094:Spermatozoa / Q000002:abnormalities; D014594:Uterine Neoplasms / Q000150:complications / Q000453:epidemiology
chemical_list: D011374:Progesterone