title: Characterizing dog breed differentiation with microsatellite markers.
abstract: Estimates of dog breed differentiation at microsatellite loci were obtained: (1) by contrasting data from German shepherds with a composite breed mixture sample; (2) by examining the Wahlund effect in new and published breed mixture data sets; and (3) from a comparison of published retriever and dachshund allele frequencies. In terms of F-statistics, the estimates ranged FBT = 0.22-0.30, and were therefore considerably greater than a previous estimate from allozyme data (FBT = 0.10). The new estimates are consistent with a view that the genetic basis of an average breed effectively corresponds to four genomes sampled from the total, or ancestral, dog gene pool.
authors.affiliation: Department of Basic Veterinary Sciences, University of Helsinki, Finland.
authors.forename: S
authors.initials: S
authors.lastname: Pihkanen
authors.forename: R
authors.initials: R
authors.lastname: Väinölä
authors.forename: S
authors.initials: S
authors.lastname: Varvio
mesh_terms: D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D004285:Dogs / Q000235:genetics*; D014644:Genetic Variation; D007527:Isoenzymes / Q000235:genetics; D018895:Microsatellite Repeats; D015203:Reproducibility of Results; D013045:Species Specificity
chemical_list: D007527:Isoenzymes