A follow-up study of five cases of aluminosis.
Five men were investigated after having pulmonary aluminosis due to exposure to aluminium pyrotechnic flake powder during the late 1940s. Two of the men had died 6 years and 20 years after exposure respectively, due to their lung disease. One man had died from heart failure 34 years after the end of exposure. Today, more than 40 years after exposure, two men were available for investigation. They had no respiratory symptoms and their vital lung capacities had not deteriorated during these years. One of the two survivors had developed a dementia with motor disturbances, which is not consistent with Alzheimer's dementia. This man had a very high concentration of aluminium in his cerebrospinal fluid. The other survivor had a normal concentration and was not demented.
Sjögren
B
B
Department of Occupational Medicine, Swedish National Institute for Working Life, Solna.
Ljunggren
K G
KG
Almkvist
O
O
Frech
W
W
Basun
H
H
D000328:Adult; D000368:Aged; D000535:Aluminum / Q000009:adverse effects*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology; D011009:Pneumoconiosis / Q000175:diagnosis / Q000401:mortality / Q000503:physiopathology; D011379:Prognosis; D012129:Respiratory Function Tests; D015996:Survival Rate
D000535:Aluminum