title: Endoscopic sphincterotomy: 7-year experience.
abstract: The present study documents the indications and results of endoscopic sphincterotomy (ES) performed over 7 years in a surgical endoscopy unit. Potential improvement of results over this time period was analyzed. ES was associated with rare but undesirable morbidity and mortality. Specific improvement of results over time has not been reported. ES was attempted in 706 patients (336 men, 370 women) from 1987 to 1994 and was accomplished in 689 patients (97.6%). Complications occurred in 50 patients (7.1%), 13 of whom required emergency operative intervention. The overall 30-day mortality was 4.7% (n = 33), and procedure-related mortality was 0. 7% (n = 5). There was a significant decrease in hospital mortality (p < 0.01) and operative intervention for procedure-related complications (p < 0.001) after 1990. Procedure-related mortality has been reduced from 1.3% to 0.3% since 1990 (p = 0.1). ES in emergency situations or for malignant biliary obstruction did not adversely affect the outcome. It was concluded that ES can be performed safely in most patients. With increasing experience, procedure-related morbidity and mortality can possibly be reduced.
authors.affiliation: Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.
authors.forename: C Y
authors.initials: CY
authors.lastname: Lo
authors.forename: E C
authors.initials: EC
authors.lastname: Lai
authors.forename: C M
authors.initials: CM
authors.lastname: Lo
authors.forename: F P
authors.initials: FP
authors.lastname: Mok
authors.forename: K M
authors.initials: KM
authors.lastname: Chu
authors.forename: C L
authors.initials: CL
authors.lastname: Liu
authors.forename: S T
authors.initials: ST
authors.lastname: Fan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D016717:Sphincterotomy, Endoscopic / Q000009:adverse effects / Q000401:mortality / Q000706:statistics & numerical data; D016896:Treatment Outcome