[Prevalence of HPV infection and histologic correlations].
476 patients with cervical lesions were examined for HPV presence in the lower genital tract. The ViraPap/ViraType detection set was used. Prevalence of low oncogenic risk group of HPV types (LR-HPV) was 12.2% a that of intermediate and high risk group (HR-HPV) was 28.5%. It is compared with control series of 168 women undergoing interruption of pregnancy (prevalence of LR-HPV 3.0% and of HR-HPV 13.7%) and with a control series of 137 STD (sexually transmitted disease) bearers (prevalence of LR-HPV 3.6% and of HR-HPV 19.0%). HR-HPV positivity was found in 37.8% of patients with CIN I, 46.7% with CIN II and 35.3% with CIN III. 16 of 20 cases (80%) with invasive cervical cancer were HR-HPV positive. The authors confirmed a statistically significant difference of HR-HPV positivity between series of women with interruption of pregnancy, with CIN and with invasive cervical cancer. Among HR-HPV positive cases, 76.5% had CIN or invasive cancer of cervix. The role of HPV testing in clinical management of cervical lesions is evaluated and considered meaningful by authors.
Freitag
P
P
II. gynek.-porod. klinika 1. LF UK a VFN, Praha.
Drazd'áková
M
M
Zivný
J
J
D005260:Female; D006801:Humans; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology; D015995:Prevalence; D012749:Sexually Transmitted Diseases / Q000821:virology; D014412:Tumor Virus Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology; D014552:Urinary Tract Infections / Q000821:virology; D002578:Uterine Cervical Dysplasia / Q000821:virology