title: [Cesarean section in a patient with a congenital deficit of antithrombin III: apropos of a case].
abstract: Antithrombin III (AT III) is a physiological inhibitor of coagulation. AT III deficit, whether congenital or acquired, results in a state of hypercoagulability characterized by recurring instances of venous thrombosis in young people. Although AT III levels normally change little during pregnancy, a deficit can be associated to the appearance of recurring thromboembolism and the need to perform cesarean section increases the risk. We report a cesarean section under general anesthesia in a patient with congenital AT III, reviewing the etiology and pathophysiology of this entity as well as its treatment.
authors.affiliation: Servicio de Anestesiología y Reanimación, Hospital General Universitario Gregorio Marañón, Madrid.
authors.forename: M C
authors.initials: MC
authors.lastname: Benito
authors.forename: M L
authors.initials: ML
authors.lastname: Sánchez
authors.forename: M V
authors.initials: MV
authors.lastname: Alvarez
authors.forename: P
authors.initials: P
authors.lastname: Sánchez
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D020152:Antithrombin III Deficiency; D001778:Blood Coagulation Disorders / Q000151:congenital / Q000628:therapy; D002585:Cesarean Section; D005260:Female; D006801:Humans; D017762:Nadroparin / Q000627:therapeutic use; D011247:Pregnancy
chemical_list: D000925:Anticoagulants; D017762:Nadroparin
vernacular_title: Cesárea en una paciente con déficit congénito de antitrombina III: a propósito de un case.