Localization of a gene coding for the phospholipase A2-L subtype (PLA2L) to human chromosome 8q24-qter.
Phospholipases A2 (PLA2) form an extended class of enzymes that play an important role in signal transduction. Phospholipase A2-like (PLA2L) belongs to the secreted forms of phospholipases A2, but constitutes a new subgroup. We have assigned the gene for this enzyme to human chromosome 8q24-qter using fluorescence in situ hybridization and radiation hybrid mapping techniques.
Meyer
A H
AH
Preclinical Research, Sandoz Pharma Limited, Basel, CH-4002, Switzerland.
Schmuck
K
K
Morel
C
C
Wishart
W
W
Lübbert
H
H
Engels
P
P
D000818:Animals; D002874:Chromosome Mapping / Q000379:methods; D018244:Chromosomes, Artificial, Yeast / Q000235:genetics; D002898:Chromosomes, Human, Pair 8 / Q000235:genetics* / Q000528:radiation effects; D018076:DNA, Complementary / Q000235:genetics; D005796:Genes; D006801:Humans; D006822:Hybrid Cells / Q000528:radiation effects / Q000648:ultrastructure; D017404:In Situ Hybridization, Fluorescence; D010741:Phospholipases A / Q000235:genetics*; D054467:Phospholipases A2; D012559:Schizophrenia / Q000235:genetics
D018076:DNA, Complementary; D010741:Phospholipases A; D054467:Phospholipases A2