GELSTATS: a computer program for population genetics analyses using VNTR multilocus probe data.
GELSTATS, a computer program for population genetics analyses utilizing genetic markers revealed with variable number tandem repeat (VNTR) multilocus probes, is described and made available (both as C++ source code and as an executable DOS program). The program calculates several population genetics parameters, including: (i) individual and population band numbers; (ii) population bands exhibiting complete linkage (redundant examples of such bands can be removed in subsequent analyses); (iii) similarity (fraction of bands shared) between individuals and average similarity within and between designated groups; (iv) estimated probability that two individuals chosen at random will have identical band profiles; (v) heterozygosity estimates for designated groups; and (vi) Fst estimates. Nonparametric permutation methods are used to assess the significance of differences in both within- and between-group similarity. A jackknife test for heterozygosity differences between groups is also computed. Examples of GELSTATS analyses illustrate some features of the program.
Rogstad
S H
SH
University of Cincinnati, OH, USA. rogstad@ucbeh.san.uc.edu
Pelikan
S
S
D000818:Animals; D016172:DNA Fingerprinting / Q000379:methods*; D015342:DNA Probes; D008040:Genetic Linkage; D005819:Genetic Markers / Q000235:genetics*; D005828:Genetics, Population; D006579:Heterozygote; D006801:Humans; D018598:Minisatellite Repeats / Q000235:genetics*; D012984:Software; D018709:Statistics, Nonparametric; D014907:Whales / Q000235:genetics
D015342:DNA Probes; D005819:Genetic Markers