title: Distribution of Corynebacterium renale among apparently healthy rats.
abstract: We examined the distribution of Corynebacterium renale, a causative agent of urinary calculus, in clinically normal rats at 6 animal facilities in Japan. Swabs of the vulva and vaginal vestibule or prepuce of the rats were cultured for isolation of the organisms. C. renale has been isolated at only one animal facility, where cases of urinary calculus were reported several years ago. In this facility, 32% of female (43/135) and 22% of male (18/82) rats, 4-28 weeks old, were positive for C. renale. In contrast, 92 female and 169 male rats at other facilities without a history of the disease were negative for the organisms.
authors.affiliation: Institute for Animal Experimentation, Hokkaido University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Osanai
authors.forename: T
authors.initials: T
authors.lastname: Ohyama
authors.forename: N
authors.initials: N
authors.lastname: Kikuchi
authors.forename: T
authors.initials: T
authors.lastname: Takahashi
authors.forename: N
authors.initials: N
authors.lastname: Kasai
authors.forename: T
authors.initials: T
authors.lastname: Hiramune
mesh_terms: D000818:Animals; D003352:Corynebacterium / Q000302:isolation & purification*; D003354:Corynebacterium Infections / Q000382:microbiology / Q000662:veterinary*; D005260:Female; D008297:Male; D010413:Penis / Q000382:microbiology; D051381:Rats; D011919:Rats, Inbred Strains / Q000382:microbiology*; D012376:Rodent Diseases / Q000382:microbiology*; D014545:Urinary Calculi / Q000382:microbiology / Q000662:veterinary; D014621:Vagina / Q000382:microbiology; D014844:Vulva / Q000382:microbiology