title: Neuro-Behçet disease presenting with internuclear ophthalmoplegia.
abstract: OBJECTIVE
  To report a case of isolated internuclear ophthalmoplegia in a patient with neuro-Behçet's disease.
  
  
  METHODS
  We evaluated the patient's clinical course.
  
  
  RESULTS
  The patient had isolated internuclear ophthalmoplegia and headache. Subsequent cerebrospinal fluid study revealed marked pleocytosis predominated by lymphocytes (61%) and polymorphonuclear cells (35%), increased protein content, and normal glucose level. A magnetic resonance imaging study with T2-weighted image demonstrated a hyperintense area in the medial longitudinal fasciculus.
  
  
  CONCLUSIONS
  Colchicine treatment of neuro-Behçet's disease caused marked improvement in the symptoms in this case, and the midbrain lesion completely disappeared after treatment.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Kyoto University, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Masai
authors.forename: S
authors.initials: S
authors.lastname: Kashii
authors.forename: H
authors.initials: H
authors.lastname: Kimura
authors.forename: H
authors.initials: H
authors.lastname: Fukuyama
mesh_terms: D000208:Acute Disease; D000328:Adult; D001528:Behcet Syndrome / Q000175:diagnosis*; D001921:Brain / Q000473:pathology; D002555:Cerebrospinal Fluid / Q000166:cytology; D003078:Colchicine / Q000627:therapeutic use; D004172:Diplopia / Q000175:diagnosis; D006074:Gout Suppressants / Q000627:therapeutic use; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D009504:Neutrophils / Q000473:pathology; D009886:Ophthalmoplegia / Q000175:diagnosis*; D014792:Visual Acuity
chemical_list: D006074:Gout Suppressants; D003078:Colchicine