title: Progressive outer retinal necrosis in an immunocompetent patient.
abstract: Progressive outer retinal necrosis syndrome is a variant of necrotizing herpetic retinopathy, a group of retinal infections caused by the herpes viruses. It has been described only in immunosuppressed patients. We present a healthy immunocompetent 16-year-old male who suffered a bilateral progressive outer retinal necrosis. Varicella-zoster virus infection was confirmed on the basis of serologic study. Treatment with intravenous acyclovir and oral prednisone was successful.
authors.affiliation: Department of Ophthalmology, Hospital Universitario Virgen del Rocio, Seville, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Carrillo-Pacheco
authors.forename: M C
authors.initials: MC
authors.lastname: Vazquez-Marouschek
authors.forename: F
authors.initials: F
authors.lastname: Lopez-Checa
authors.forename: J
authors.initials: J
authors.lastname: Sanchez-Roman
mesh_terms: D000212:Acyclovir / Q000008:administration & dosage; D000284:Administration, Oral; D000293:Adolescent; D000888:Antibodies, Anti-Idiotypic / Q000276:immunology; D000914:Antibodies, Viral / Q000032:analysis; D000998:Antiviral Agents / Q000008:administration & dosage; D018450:Disease Progression; D004359:Drug Therapy, Combination; D015828:Eye Infections, Viral / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D005938:Glucocorticoids / Q000008:administration & dosage; D006562:Herpes Zoster / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D014645:Herpesvirus 3, Human / Q000276:immunology; D006801:Humans; D016867:Immunocompromised Host / Q000276:immunology*; D007075:Immunoglobulin M / Q000276:immunology; D007262:Infusions, Intravenous; D008297:Male; D011241:Prednisone / Q000008:administration & dosage; D015882:Retinal Necrosis Syndrome, Acute / Q000188:drug therapy / Q000209:etiology* / Q000276:immunology; D014792:Visual Acuity
chemical_list: D000888:Antibodies, Anti-Idiotypic; D000914:Antibodies, Viral; D000998:Antiviral Agents; D005938:Glucocorticoids; D007075:Immunoglobulin M; D011241:Prednisone; D000212:Acyclovir