title: The antiproliferative effect of leflunomide on vascular smooth muscle cells in vitro is mediated by selective inhibition of pyrimidine biosynthesis.
authors.affiliation: Department of Cardiothoracic Surgery, Falk CVRB, Stanford University School of Medicine, California 94305-5247, USA.
authors.forename: R V
authors.initials: RV
authors.lastname: Nair
authors.forename: W
authors.initials: W
authors.lastname: Cao
authors.forename: R E
authors.initials: RE
authors.lastname: Morris
mesh_terms: D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D006086:Graft vs Host Disease / Q000188:drug therapy / Q000276:immunology / Q000517:prevention & control; D006151:Guanosine / Q000494:pharmacology; D009131:Muscle, Smooth, Vascular / Q000166:cytology* / Q000187:drug effects / Q000378:metabolism; D011743:Pyrimidines / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D051381:Rats; D014529:Uridine / Q000494:pharmacology
chemical_list: D011743:Pyrimidines; D006151:Guanosine; D014529:Uridine