title: Portal vein obstruction accompanied by intrahepatic stones.
abstract: This study was conducted to clarify the pathogenesis of portal vein obstruction (PVO) associated with intrahepatic stones. Five cases with PVO and intrahepatic stones were studied retrospectively. The coincidence rate of PVO in intrahepatic stones was 5.8% (5 of 86 cases), and that of intrahepatic stones in PVO, 45.5% (5 of 11 cases). All cases had one or more symptoms of cholangitis, such as high-grade fever, abdominal pain, and jaundice prior to diagnosis of PVO. The portal vein was occluded at the main trunk in 4 and in the left branch in 1. Intrahepatic stones were found in bilateral hepatic lobes in 3 and in the left lobe in 2. Numerous calcium bilirubinate stones were packed in dilatated intrahepatic bile ducts of an excised specimen of the liver. Microscopically, arterial structures could be seen, but the portal vein ceased to be evident about the involved bile duct. Based on the results of this study, persistent cholangitis and packed gallstones were concluded essential to the development of PVO accompanied by intrahepatic stones.
authors.affiliation: Second Department of Surgery, Faculty of Medicine, Kagoshima University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: T
authors.initials: T
authors.lastname: Komokata
authors.forename: A
authors.initials: A
authors.lastname: Ikoma
authors.forename: A
authors.initials: A
authors.lastname: Yamaoka
authors.forename: Y
authors.initials: Y
authors.lastname: Fukumoto
authors.forename: A
authors.initials: A
authors.lastname: Taira
mesh_terms: D000328:Adult; D000368:Aged; D001649:Bile Duct Diseases / Q000150:complications / Q000000981:diagnostic imaging; D001653:Bile Ducts, Intrahepatic / Q000000981:diagnostic imaging; D002761:Cholangitis / Q000150:complications* / Q000000981:diagnostic imaging; D002769:Cholelithiasis / Q000150:complications* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D016491:Peripheral Vascular Diseases / Q000000981:diagnostic imaging / Q000209:etiology; D011169:Portal Vein / Q000000981:diagnostic imaging; D011859:Radiography; D012189:Retrospective Studies