Does leptin contribute to diabetes caused by obesity?
Taylor
S I
SI
Diabetes Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892-1829, USA. simeon_taylor@nih.gov
Barr
V
V
Reitman
M
M
D017667:Adipocytes / Q000502:physiology; D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism; D003920:Diabetes Mellitus / Q000209:etiology*; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology*; D015971:Gene Expression Regulation, Enzymologic; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D007329:Insulin Antagonists; D055504:Insulin Receptor Substrate Proteins; D007333:Insulin Resistance; D020738:Leptin; D008099:Liver / Q000378:metabolism; D051379:Mice; D008820:Mice, Obese; D009765:Obesity / Q000503:physiopathology; D010729:Phosphoenolpyruvate Carboxykinase (GTP) / Q000235:genetics; D010750:Phosphoproteins / Q000378:metabolism; D010766:Phosphorylation; D011506:Proteins / Q000378:metabolism* / Q000494:pharmacology; D011972:Receptor, Insulin / Q000378:metabolism; D011956:Receptors, Cell Surface; D054411:Receptors, Leptin; D015398:Signal Transduction
D002352:Carrier Proteins; C526292:IRS1 protein, human; D007328:Insulin; D007329:Insulin Antagonists; D055504:Insulin Receptor Substrate Proteins; C526295:Irs1 protein, mouse; C515448:LEPR protein, human; D020738:Leptin; D010750:Phosphoproteins; D011506:Proteins; D011956:Receptors, Cell Surface; D054411:Receptors, Leptin; C515447:leptin receptor, mouse; D011972:Receptor, Insulin; D010729:Phosphoenolpyruvate Carboxykinase (GTP)