title: [Perniosis and lupus anticoagulant].
abstract: Five patients with acral chilblains and lupus anticoagulant activity revealed by coagulation analysis are reported. Three patients suffered a systemic lupus erythematosus, and two of them a completely developed antiphospholipid syndrome as well. Another case had chronic cutaneous lupus with only facial discoid lesions, and in the last one the lupus anticoagulant was likely related to a chronic liver infection of hepatitis B virus because she had not erythematous lupus. There are few dermatologic references about chilblain associated to lupus anticoagulant. Certain evidences suggest a pathogenic relation of this findings.
authors.affiliation: Servicio de Dermatología, Hospital Universitario Doce de Octubre, Madrid.
authors.forename: D
authors.initials: D
authors.lastname: de Argila Fernández-Aurán
authors.forename: F
authors.initials: F
authors.lastname: Revenga Arranz
authors.forename: L
authors.initials: L
authors.lastname: Iglesias Díez
mesh_terms: D000293:Adolescent; D000328:Adult; D002647:Chilblains / Q000097:blood*; D005260:Female; D006229:Hand Dermatoses / Q000097:blood*; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000097:blood*
chemical_list: D016682:Lupus Coagulation Inhibitor
vernacular_title: Perniosis y anticoagulante lúpico.