title: Cranial nerve and hearing function after combined-approach surgery for glomus jugulare tumors.
abstract: In this retrospective study, oncologic and functional results of 46 patients treated for glomus jugulare tumor are reported. The standard surgical approach was the combined transmastoid-transcervical approach, modified according to the individual tumor growth, and eventually combined with a transtemporal or a suboccipital approach. Complete tumor removal resulted in a cure rate of 90%. New-onset cranial nerve palsies developed in less than 22% of patients. In 54% of cases it was possible to retain middle ear function. From a total of 12 patients with incomplete tumor removal and postoperative irradiation, progressive tumor growth was noted in 4 patients, and was controlled by salvage irradiation or surgery. Radical tumor removal by ablative surgery can be modified by efforts to reduce multilating resections. In their place, individually tailored and combined multidirectional surgical approaches may allow total tumor removal with lower morbidity.
authors.affiliation: Department of Otorhinolaryngology, University of Erlangen-Nuremberg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Gjuric
authors.forename: S
authors.initials: S
authors.lastname: Rüdiger Wolf
authors.forename: M E
authors.initials: ME
authors.lastname: Wigand
authors.forename: M
authors.initials: M
authors.lastname: Weidenbecher
mesh_terms: D003131:Combined Modality Therapy; D003389:Cranial Nerve Diseases / Q000453:epidemiology* / Q000517:prevention & control; D004432:Ear, Middle / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D005925:Glomus Jugulare Tumor / Q000532:radiotherapy / Q000601:surgery*; D006311:Hearing Disorders / Q000453:epidemiology* / Q000517:prevention & control; D006801:Humans; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D011183:Postoperative Complications / Q000453:epidemiology* / Q000517:prevention & control; D012189:Retrospective Studies; D013997:Time Factors