title: Synthesis and activity of N epsilon-aminocaproyl-L-norleucine derivatives.
abstract: Five new derivatives of epsilon-aminocaproyl-L-norleucine were synthesized. Antifibrinolytic and anticaseinolytic activities were tested. All tested compounds were inhibitors of plasmin.
authors.affiliation: Institute of Chemistry, Branch of Warsaw University in Białystok, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Midura-Nowaczek
authors.forename: I
authors.initials: I
authors.lastname: Bruzgo
authors.forename: W
authors.initials: W
authors.lastname: Roszkowska-Jakimiec
authors.forename: K
authors.initials: K
authors.lastname: Worowski
mesh_terms: D015119:Aminocaproic Acid / Q000737:chemistry; D000933:Antifibrinolytic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002364:Caseins / Q000378:metabolism*; D004024:Dicyclohexylcarbodiimide / Q000737:chemistry; D015195:Drug Design; D005341:Fibrinolysin / Q000378:metabolism*; D009646:Norleucine / Q000031:analogs & derivatives* / Q000737:chemistry*; D013329:Structure-Activity Relationship; D014230:Triazoles / Q000737:chemistry
chemical_list: D000933:Antifibrinolytic Agents; D002364:Caseins; C103892:N(6)-aminocaproylnorleucine; D014230:Triazoles; D004024:Dicyclohexylcarbodiimide; D009646:Norleucine; C011852:1-hydroxybenzotriazole; D005341:Fibrinolysin; D015119:Aminocaproic Acid