title: [Adequacy of the pharmacologic treatment to the recommendations of a performance protocol in hypercholesterolemia in primary care].
abstract: OBJECTIVE
  To evaluate whether hypolipaemiant treatment in patients with hypercholesterolaemia (HC) corresponds to the recommendations in a primary care diagnosis and treatment protocol.
  
  
  METHODS
  Descriptive observational study.
  
  
  METHODS
  Primary care centre.
  
  
  METHODS
  304 patients whose long-term prescription records recorded hypolipaemiant drugs.
  
  
  RESULTS
  Average age was 62.7 and 198 were women. 176 presented simple HC and 125 mixed dyslipaemia. 46 had a history of ischaemic cardiopathy. Pre-treatment LDL-cholesterol (LDL-c) was recorded for 224; 168 of them had 2 or more cardiovascular risk factors. Of the 202 who had a record of post-treatment LDL-c, 163 were at level III of risk, which went down to 47 at 6 months. The values before and after medication were as follows: total cholesterol (TC) 290.3 mg/dl and 246.2 mg/dl; LDL-c 207.8 mg/dl and 166.0 mg/dl; HDL-cholesterol 50.5 mg/dl and 53.1 mg/dl; and triglycerides (TG) 156.1 mg/dl and 133.6 mg/dl. Mean reduction of TC and LDL-c was greater in the patients treated with statins that in those treated with fibrates. Decrease in TG was greater with fibrates.
  
  
  CONCLUSIONS
  Treatment was initiated when LDL-c figures were over the limit specified in the protocol. In most cases this was because of the accumulation of cardiovascular risk factors.
authors.affiliation: Unidad Docente de MFyC de Barcelona, Institut Català de la Salut.
authors.forename: G
authors.initials: G
authors.lastname: Martínez
authors.forename: S
authors.initials: S
authors.lastname: Quiñones
authors.forename: L
authors.initials: L
authors.lastname: Castillo
authors.forename: A
authors.initials: A
authors.lastname: Ramos
authors.forename: E
authors.initials: E
authors.lastname: Avellana
authors.forename: R
authors.initials: R
authors.lastname: Ciurana
authors.forename: M
authors.initials: M
authors.lastname: Mata
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002985:Clinical Protocols; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications; D017678:Sex Distribution
chemical_list: D000960:Hypolipidemic Agents; D008055:Lipids
vernacular_title: Adecuación del tratamiento farmacológico a las recomendaciones de un protocolo de actuación ante la hipercolesterolemia en atención primaria.