title: Treatment for patients with recurrent abortion with positive antiphospholipid antibodies using a traditional Chinese herbal medicine.
abstract: Twelve patients with recurrent abortion who had shown positive antiphospholipid antibodies were treated through the administration of a Japanese modified traditional Chinese herbal medicine Sairei-To (Chan ling-Tang) The patients had experienced a total of 27 spontaneous abortions in their previous pregnancies and had no other pregnancy history except for one patient. The patients were treated with 9.0 g of Sairei-To per day before their next pregnancy. The positive value of antiphospholipid antibodies returned to negative in 9 patients out of 12 patients through the treatment. Out of 12 patients, in 10 patients, their new pregnancy continued uneventfully and delivered an offspring (Success rate: 83.3%). Thus, the current treatment was considered to be an effective therapy for patients with recurrent abortion who were found to be positive for antiphospholipid antibodies.
authors.affiliation: Department of Obstetrics and Gynecology, Niigata University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Takakuwa
authors.forename: M
authors.initials: M
authors.lastname: Yasuda
authors.forename: I
authors.initials: I
authors.lastname: Hataya
authors.forename: N
authors.initials: N
authors.lastname: Sekizuka
authors.forename: M
authors.initials: M
authors.lastname: Tamura
authors.forename: M
authors.initials: M
authors.lastname: Arakawa
authors.forename: M
authors.initials: M
authors.lastname: Higashino
authors.forename: I
authors.initials: I
authors.lastname: Hasegawa
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
mesh_terms: D000026:Abortion, Habitual / Q000188:drug therapy* / Q000276:immunology*; D000328:Adult; D017152:Antibodies, Antiphospholipid / Q000097:blood*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D011247:Pregnancy
chemical_list: D017152:Antibodies, Antiphospholipid; D004365:Drugs, Chinese Herbal; C080903:sairei-to