title: Demonstration of frontal hypoperfusion in benign exertional headache by Technetium-99m-HMPAO SPECT.
abstract: We present a case of benign exertional headache (BEH) in a 15-yr-old boy. The patient suffered from exclusively exercise-induced headaches with migraine-like accompanying symptoms. No pathology could be detected by routine cardiovascular or neurological examinations by CT. The postexercise 99mTc-HMPAO brain SPECT performed during the provoked headache attack showed asymmetric bifrontal hypoperfusion. A second 99mTc-HMPAO study during a symptom-free phase under resting conditions was normal. The detection of impaired regional cerebral blood flow (rCBF) by 99mTc-HMPAO brain SPECT indicates a perfusion-related pathology in this type of headache. Analysis of rCBF with 99mTc-HMPAO in larger studies could be helpful in the clarification of BEH pathogenesis.
authors.affiliation: Department of Nuclear Medicine, Ondokuz Mayis University Hospital, Samsun, Turkey.
authors.forename: T
authors.initials: T
authors.lastname: Başoglu
authors.forename: T
authors.initials: T
authors.lastname: Ozbenli
authors.forename: I
authors.initials: I
authors.lastname: Bernay
authors.forename: M
authors.initials: M
authors.lastname: Sahin
authors.forename: A
authors.initials: A
authors.lastname: Onur
authors.forename: A E
authors.initials: AE
authors.lastname: Demirçali
authors.forename: C
authors.initials: C
authors.lastname: Coşkun
authors.forename: T
authors.initials: T
authors.lastname: Onen
mesh_terms: D000293:Adolescent; D001921:Brain / Q000000981:diagnostic imaging*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D006261:Headache / Q000000981:diagnostic imaging* / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D008297:Male; D015609:Organotechnetium Compounds; D010091:Oximes; D005082:Physical Exertion; D012420:Running; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime