Transport vesicle docking: SNAREs and associates.
Proteins that function in transport vesicle docking are being identified at a rapid rate. So-called v- and t-SNAREs form the core of a vesicle docking complex. Additional accessory proteins are required to protect SNAREs from promiscuous binding and to deprotect SNAREs under conditions in which transport vesicle docking should occur. Because access to SNAREs must be regulated, other proteins must also contain specificity determinants to accomplish delivery of transport vesicles to their distinct and specific membrane targets.
Pfeffer
S R
SR
Department of Biochemistry, Stanford University School of Medicine, California 94305-5307, USA.
D000818:Animals; D001692:Biological Transport; D003594:Cytoplasmic Granules / Q000502:physiology*; D006801:Humans; D008565:Membrane Proteins / Q000502:physiology*; D050600:SNARE Proteins; D033921:Vesicular Transport Proteins
D008565:Membrane Proteins; D050600:SNARE Proteins; D033921:Vesicular Transport Proteins