[Can the type of GnRH used during long in vitro fertilization protocols influence the pregnancy rate?].
Luteal defect is common during IVF cycles using GnRH agonist. It could be interesting to make up for this problem by using short acting GnRH agonist (effective for 24 hours), more handy at the end of the stimulation. 160 patients included in a long IVF protocol at the Bordeaux CHRU FIV center have been randomized, from September 1993 to August 1994, for the analog's choice (long or short) at the beginning of the stimulation. The stimulation's parameters, the hormonal dosages and the pregnancy rate are independent of the galenic form used. In close, the use of long-acting GnRH analog (sympler to use) sems preferable.
Librati
C
C
Centre de FIV: Maternité CHRU de Bordeaux, Hôpital Pellegrin.
Hocke
C
C
Filet
J P
JP
Papaxanthos
A
A
Mene
D
D
Dulucq
M C
MC
Leng
J J
JJ
D000328:Adult; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D016729:Leuprolide / Q000627:therapeutic use*; D008186:Luteolytic Agents / Q000627:therapeutic use*; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011446:Prospective Studies; D013997:Time Factors; D017329:Triptorelin Pamoate / Q000627:therapeutic use*
D008186:Luteolytic Agents; D017329:Triptorelin Pamoate; D016729:Leuprolide
Le type d'analogue de la GnRH utilisé au cours des protocoles longs en FIV peut-il influencer les taux de grossesse?