[The effect of L-arginine on the NADPH-diaphorase activity in Drosophila melanogaster homogenates].
It was shown that L-arginine (up to 0.5 mM) competitively inhibits the NADPH-diaphorase activity in drosophila melanogaster. The value of inhibition constant is equal to 103 microM. In the presence of higher concentration of L-arginine total NADPH-diaphorase activity includes not only the L-arginine inhibited component, but also the non-inhibited one.
Oparina
T I
TI
Myl'nikov
S V
SV
D000818:Animals; D001120:Arginine / Q000494:pharmacology*; D001667:Binding, Competitive / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004331:Drosophila melanogaster / Q000187:drug effects* / Q000201:enzymology; D009252:NADPH Dehydrogenase / Q000037:antagonists & inhibitors / Q000187:drug effects* / Q000378:metabolism; D019001:Nitric Oxide Synthase / Q000187:drug effects / Q000378:metabolism; D013379:Substrate Specificity / Q000187:drug effects
D001120:Arginine; D019001:Nitric Oxide Synthase; D009252:NADPH Dehydrogenase
Vliianie L-arginina na NADPH-diaforaznuiu aktivnost' v gomogenatakh Drosophila melanogaster.