title: [Pancreatoduodenectomy in the treatment of carcinoma of Vater's ampulla].
abstract: OBJECTIVE
  To analyze clinical characteristics, diagnostic methods, intraoperative findings, morbidity & mortality and outcome of a series of patients with ampullary adenocarcinoma.
  
  
  METHODS
  Retrospective analysis.
  
  
  METHODS
  Tertiary-care medical center.
  
  
  METHODS
  Thirty four consecutive patients who underwent radical resection between 1960 and 1992.
  
  
  RESULTS
  The most frequent findings were jaundice (91%), weight loss (44%) and palpable gallbladder (42%). Thirty-three patients (97%) underwent Whipple resection and one total pancreatectomy (3%). The postoperative mortality was 15%. Overall survival at 1, 5, 10 and 14 years was 67, 36, 25 and 17% respectively. Fourteen patients died of tumor recurrence developed more than five years after the resection.
  
  
  CONCLUSIONS
  Radical resection for ampullary carcinoma remains the procedure of first choice in these patients.
authors.affiliation: División de Cirugía, Instituto Nacional de la Nutrición Salvador Zubirán, México, D.F.
authors.forename: J C
authors.initials: JC
authors.lastname: Morales-Linares
authors.forename: T J
authors.initials: TJ
authors.lastname: Gómez-Méndez
authors.forename: C
authors.initials: C
authors.lastname: Chan
authors.forename: L
authors.initials: L
authors.lastname: Quintanilla-Martínez
authors.forename: L
authors.initials: L
authors.lastname: Uscanga
authors.forename: G
authors.initials: G
authors.lastname: Robles-Díaz
authors.forename: L
authors.initials: L
authors.lastname: de la Garza
authors.forename: M
authors.initials: M
authors.lastname: Campuzano
authors.forename: M F
authors.initials: MF
authors.lastname: Herrera
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D000328:Adult; D000368:Aged; D014670:Ampulla of Vater / Q000601:surgery*; D003138:Common Bile Duct Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D016577:Pancreaticoduodenectomy / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome
vernacular_title: Pancreatoduodenectomía en el tratamiento de carcinoma del ámpula de Vater.