title: Respiratory effects of CO2 pneumoperitoneum during transperitoneal laparoscopic urological surgery.
abstract: OBJECTIVE
  To evaluate the effects of CO2 pneumoperitoneum on respiratory function during urological laparoscopic surgery with exposure of the retroperitoneal space in the lateral decubitus position.
  
  
  METHODS
  Arterial blood gas analysis and measurements of the partial pressure of CO2 in exhaled gas (PetCO2) were performed during CO2 pneumoperitoneum in 12 patients who underwent transperitoneal laparoscopic surgery for the retroperitoneal organs (the retroperitoneal group): the results were compared to those of 11 patients who underwent laparoscopic varicocelectomy (the varicocele group) with the same anesthesia and intra-abdominal pressure.
  
  
  RESULTS
  The increase in PaCO2 and PetCO2 and the decrease in arterial pH during CO2 insufflation were significantly greater in the retroperitoneal group than in the varicocele group. PaCO2, PetCO2 and arterial pH continued to change in the retroperitoneal group, whereas these values reached a plateau at 30 min after the beginning of CO2 insufflation in the varicocele group.
  
  
  CONCLUSIONS
  The respiratory effects of CO2 pneumoperitoneum are more pronounced during laparoscopic urological surgery with opening of the retroperitoneum. It is possible that exposure of the retroperitoneal space increased CO2 absorption during insufflation.
authors.affiliation: Department of Urology, Kansai Medical University, Osaka, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Matsuda
authors.forename: K
authors.initials: K
authors.lastname: Fujise
authors.forename: S
authors.initials: S
authors.lastname: Matsumoto
authors.forename: O
authors.initials: O
authors.lastname: Mikami
authors.forename: J
authors.initials: J
authors.lastname: Uchida
authors.forename: K
authors.initials: K
authors.lastname: Shingu
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001784:Blood Gas Analysis; D002245:Carbon Dioxide / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010535:Laparoscopy / Q000009:adverse effects* / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010313:Partial Pressure; D011028:Pneumoperitoneum, Artificial / Q000009:adverse effects*; D012119:Respiration / Q000502:physiology; D012187:Retroperitoneal Space / Q000601:surgery; D014646:Varicocele / Q000601:surgery
chemical_list: D002245:Carbon Dioxide