Should cryosurgery be considered a therapeutic option in localized prostate cancer?
Cryosurgical ablation of the prostate currently is under investigation as a potential treatment for localized prostate cancer. Results to date indicate that the majority of patients have negative biopsies and a marked reduction in prostate-specific antigen levels following cryotherapy. This treatment, however, is associated with significant side effects, notably bladder outflow obstruction, impotence, and incontinence, and its long-term durability is still unknown.
Connolly
J A
JA
Department of Urology, University of California San Francisco/Mt. Zion Cancer Center, USA.
Shinohara
K
K
Presti
J C
JC
Carroll
P R
PR
D003452:Cryosurgery / Q000379:methods; D006801:Humans; D008297:Male; D018579:Patient Selection; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000097:blood / Q000601:surgery*
D017430:Prostate-Specific Antigen