title: Clinical results of common strategies used to revise infrainguinal vein grafts.
abstract: OBJECTIVE
  Patients who have failing infrainguinal bypass grafts or failed grafts reopened with lytic therapy represent a group at high risk of subsequent failure. Previous studies suggest that vein patch angioplasty and jump grafting may be less durable than interposition grafting as a method of correcting graft lesions. Our objective was to assess the value of various technical strategies for graft revision in a series of autogenous infrainguinal bypass grafts and to assess how these variables might affect cumulative graft patency (CGP) rates.
  
  
  METHODS
  We retrospectively reviewed the clinical course, anatomic sites of revision, and type of revision performed on 67 grafts in 58 patients who underwent at least one revision from 1991 to 1995. Results were assessed with regression analysis and Kaplan-Meier estimates of CGP rates (p < 0.05 was considered significant).
  
  
  RESULTS
  Sixty-seven vein grafts underwent revision of 112 anatomical sites in 95 operations. Forty-nine of 67 grafts were single-segment greater saphenous vein grafts and 18 were composite (> 1 segment) grafts, with an overall 5-year CGP rate of 72%. No difference was observed between the 4-year CGP rate in grafts with hemodynamically significant distal anastomotic stenoses repaired primarily with jump grafts (n = 20, 71% CGP rate) and those with stenoses found only in the graft body (n = 41, 89% CGP rate). Vein patch angioplasty was used primarily, but not exclusively, for focal graft body stenoses (n = 35), whereas interposition grafts (n = 11) were reserved for more diffuse strictures; no significant difference in 3-year CGP rates was observed (94% and 73%, respectively).
  
  
  CONCLUSIONS
  Using an appropriate revision strategy that favors vein patch angioplasty for graft body lesions and jump grafts for distal anastomotic lesions, acceptable assisted patency rates can be achieved in grafts that are at risk for repeated failure.
authors.affiliation: Department of Surgery, New England Medical Center.
authors.forename: T R
authors.initials: TR
authors.lastname: Sullivan
authors.forename: H J
authors.initials: HJ
authors.lastname: Welch
authors.forename: M D
authors.initials: MD
authors.lastname: Iafrati
authors.forename: W C
authors.initials: WC
authors.lastname: Mackey
authors.forename: T F
authors.initials: TF
authors.lastname: O'Donnell
mesh_terms: D017130:Angioplasty / Q000379:methods; D000800:Angioplasty, Balloon; D006083:Graft Occlusion, Vascular / Q000453:epidemiology / Q000628:therapy*; D006801:Humans; D007866:Leg / Q000098:blood supply*; D015993:Life Tables; D011150:Popliteal Artery / Q000601:surgery; D012501:Saphenous Vein / Q000637:transplantation; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000453:epidemiology / Q000628:therapy*; D016909:Tibial Arteries / Q000601:surgery; D016896:Treatment Outcome; D014654:Vascular Patency