[Diagnostic value of selective cytochemical reaction to zinc in peripheral blood granulocytes].
A method for cytochemical detection of zinc in peripheral blood granulocytes with selective reaction of 8-(p-toluenesulfonyl amino)-quinoline was developed. Zinc levels in granular leukocytes were found reduced in chronic myeloleukemia and elevated in leukemoid reactions. The method may be used for the differential diagnosis of these diseases.
Gol'dberg
E D
ED
Bovt
V D
VD
Eshchenko
V A
VA
D000634:Aminoquinolines; D003937:Diagnosis, Differential; D005456:Fluorescent Dyes; D006098:Granulocytes / Q000737:chemistry*; D006651:Histocytochemistry; D006801:Humans; D007951:Leukemia, Myeloid / Q000097:blood / Q000175:diagnosis*; D007955:Leukemoid Reaction / Q000097:blood / Q000175:diagnosis*; D008163:Luminescent Measurements; D014105:Tosyl Compounds; D015032:Zinc / Q000097:blood*
D000634:Aminoquinolines; D005456:Fluorescent Dyes; D014105:Tosyl Compounds; C031480:8-(4-tolylsulfonylamino)quinoline; D015032:Zinc
Diagnosticheskoe znachenie selektivnoĭ tsitokhimicheskoĭ reaktsii na tsink v granulotsitakh perifericheskoĭ krovi.