Femoral hypoplasia and maternal diabetes: consider femoral hypoplasia/unusual facies syndrome.
Femoral hypoplasia/unusual facies syndrome (FH/UFS) is a rarely considered clinical entity that has a strong association with maternal diabetes. A case that demonstrates the prenatal morphologic and biometric abnormalities, and postnatal findings are presented. The pathogenesis and natural history of FH/UFS is discussed and contrasted with the caudal dysplasia syndrome.
Hinson
R M
RM
Department of Pediatrics, National Naval Medical Center, Bethesda, Maryland, USA.
Miller
R C
RC
Macri
C J
CJ
D000328:Adult; D003937:Diagnosis, Differential; D019066:Facies; D005260:Female; D005269:Femur / Q000002:abnormalities*; D006801:Humans; D011247:Pregnancy; D011254:Pregnancy in Diabetics; D013577:Syndrome; D016216:Ultrasonography, Prenatal