title: Elevated endoxin-like factor complicating a multifetal second trimester pregnancy: treatment with digoxin-binding immunoglobulin.
abstract: We report a case of a second trimester multifetal pregnancy with preeclampsia associated with an elevated digoxin-like immune factor. Due to the remoteness from viability the patient was offered therapy with digoxin-binding immunoglobulin. No untoward maternal effects were noted.
authors.affiliation: Bowman Gray School of Medicine, Department of Obstetrics and Gynecology, Winston-Salem, N.C., USA.
authors.forename: C D
authors.initials: CD
authors.lastname: Adair
authors.forename: V
authors.initials: V
authors.lastname: Buckalew
authors.forename: K
authors.initials: K
authors.lastname: Taylor
authors.forename: J M
authors.initials: JM
authors.lastname: Ernest
authors.forename: A H
authors.initials: AH
authors.lastname: Frye
authors.forename: C
authors.initials: C
authors.lastname: Evans
authors.forename: J C
authors.initials: JC
authors.lastname: Veille
mesh_terms: D000328:Adult; D002298:Cardenolides; D004077:Digoxin / Q000097:blood* / Q000276:immunology; D005260:Female; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000627:therapeutic use*; D011225:Pre-Eclampsia / Q000097:blood* / Q000188:drug therapy; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011272:Pregnancy, Multiple; D012503:Saponins / Q000097:blood*
chemical_list: D002298:Cardenolides; D007140:Immunoglobulin Fab Fragments; D012503:Saponins; C050199:digoxin antibodies Fab fragments; C034504:digoxin-like factors; D004077:Digoxin