[Uridine diphosphate sugar in meningiomas of the brain].
The content of uridine-diphosphate (UDP)-saccharides, such as UDP-glucose (UDPG) and UDP-N-acetylglucosamine (UDPAG) was examined in the meningiomas obtained at surgery. Typical, atypical, and anaplastic meningiomas were used. Biochemical data were compared with histological findings. The total level of UDP-saccharides (UDPG + UDPAG) in the meningiomas was demonstrated not to depend on the grade of anaplasia. A positive correlation was found between the UDPG/UDPAG ratio was from 1.73 in typical (benign) neoplasms to 6 or even higher in meningiomas with severe sings of malignancy (anaplastic meningiomas). The UDPG/UDPAG ratio seems to reflect the nature and rate of tumor growth.
Popova
G M
GM
Promyslov
M Sh
MSh
Gabibov
G A
GA
D000708:Anaplasia / Q000737:chemistry; D001921:Brain / Q000473:pathology; D001923:Brain Chemistry; D001932:Brain Neoplasms / Q000737:chemistry*; D006801:Humans; D008577:Meningeal Neoplasms / Q000737:chemistry*; D008579:Meningioma / Q000737:chemistry*; D014539:Uridine Diphosphate Sugars / Q000032:analysis*
D014539:Uridine Diphosphate Sugars
Uridindifosfatsakhara v meningiomakh golovnogo mozga.