title: [Clinical trial with tibolone in postmenopausal replacement therapy].
abstract: Estrogen deficiency is the basic change in women around the climateric stage. This hormone deficiency is different among women regarding the age and intensity of symptoms. The hormone replacement has proved its benefit on relieve of symptoms and long term effect on prevention of cardiovascular disease and osteoporosis. A new pharmacological agent Tibolona has been studied recently as replacement therapy. This work reports the results obtained with the use of Tibolona in 36 postmenopausal women. The effectiveness and security were confirmed as well as the low occurrence of side effects. It was also apparent that this therapy had a relevant effect on the psycho-emotional component and upon the improvement of sexual satisfaction and activity.
authors.affiliation: Unidad de Investigación de Enfermedades Endocrinas, Hospital de Especialidades, Centro Médico Nacional, México.
authors.forename: A
authors.initials: A
authors.lastname: Zarate
authors.forename: M
authors.initials: M
authors.lastname: Hernandez
authors.forename: R
authors.initials: R
authors.lastname: Ochoa
authors.forename: A
authors.initials: A
authors.lastname: Santos
mesh_terms: D000328:Adult; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D009652:Norpregnenes / Q000627:therapeutic use*; D017698:Postmenopause
chemical_list: D009652:Norpregnenes; C027385:tibolone
vernacular_title: Experiencia clínica con tibolona en la terapia de reemplazo hormonal en la posmenopausia.