title: Hepatic echinococcus disease: our experience over 22 years.
abstract: OBJECTIVE
  It is important to single out the indications for surgery of hydatid disease of the liver at an early stage. For this, a fully comprehensive diagnostic work up of the patient is required. Surgery represents the most effective therapy and involves resection of the cysts and their outer capsule. This must be as complete as possible.
  
  
  METHODS
  Between 1970 and June 1992, 95 patients received this combined treatment for hydatid disease although only those presenting from 1985 were followed up.
  
  
  RESULTS
  No serious complications were noted apart from pyrexia due to secondary cholangitis or reactive pleuritis. This responded quickly to antibiotics and there was no mortality. No cases of relapse occurred although one case did show evidence of reappearance of the disease on serological testing alone, all other tests being negative.
  
  
  CONCLUSIONS
  The most effective treatment for echinococcus cystic disease of the liver is radical surgery. Results are best when surgery is combined with medical therapy of benzoimidazole drugs given pre- and post-operatively. From our experience, we are now confident that surgical treatment must always be preceded and then followed by treatment with benzoimidazole antihelminthics.
authors.affiliation: 3rd Department of General Surgery, University of Rome La Sapienza.
authors.forename: G
authors.initials: G
authors.lastname: Di Matteo
authors.forename: A
authors.initials: A
authors.lastname: Bove
authors.forename: S
authors.initials: S
authors.lastname: Chiarini
authors.forename: L G
authors.initials: LG
authors.lastname: Capuano
authors.forename: E
authors.initials: E
authors.lastname: De Antoni
authors.forename: G
authors.initials: G
authors.lastname: Lanzi
authors.forename: G
authors.initials: G
authors.lastname: Lippolis
authors.forename: F P
authors.initials: FP
authors.lastname: Campana
mesh_terms: D000328:Adult; D000977:Antiparasitic Agents / Q000627:therapeutic use*; D004444:Echinococcosis, Hepatic / Q000188:drug therapy* / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D016896:Treatment Outcome
chemical_list: D000977:Antiparasitic Agents