title: Biotechnology at low Reynolds numbers.
abstract: The shrinking of liquid handling systems to the micron and submicron size range entails moving into the area of small Reynolds numbers. The fluid dynamics in this regime are very different from the macroscale. We present an intuitive explanation of how the different physics of small Reynolds numbers flow, along with microscopic sizes, can influence device design, and give examples from our own work using fluid flow in microfabricated devices designed for biological processing.
authors.affiliation: Center for Bioengineering, University of Washington, Seattle 98195-2141, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Brody
authors.forename: P
authors.initials: P
authors.lastname: Yager
authors.forename: R E
authors.initials: RE
authors.lastname: Goldstein
authors.forename: R H
authors.initials: RH
authors.lastname: Austin
mesh_terms: D001709:Biotechnology / Q000295:instrumentation* / Q000379:methods*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D007700:Kinetics; D008433:Mathematics; D008855:Microscopy, Electron, Scanning; D008904:Miniaturization; D008962:Models, Theoretical