Physico-chemical parameters of nitrate esters. A contribution to the choice of a candidate for preclinical development.
Physico-chemical parameters of new nitrate esters were carried out in order to contribute to the choice of a drug candidate for preclinical development. Thermal analysis (DSC), wettability and solubility of the compounds were investigated in this study.
Fontana
L
L
Italfarmaco Research Center, Cinisello Balsamo (MI), Italy.
Rosati
L
L
Sala
A
A
Dobetti
L
L
D002152:Calorimetry, Differential Scanning; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D015195:Drug Design; D004952:Esters / Q000737:chemistry; D009566:Nitrates / Q000737:chemistry*; D012995:Solubility; D017155:Wettability
D004952:Esters; D009566:Nitrates