Complex responses of living neurons to pacemaker inhibition: a comparison of dynamical models.
A neuron can respond to periodic inhibitory input with a variety of complex behaviors, periodic and aperiodic. We present a succession of models to test hypotheses for mechanisms underlying complex behavior generation. Model comparison using non-linear dynamics techniques indicates that long-duration IPSP aftereffects and spiking behavior are necessary for most of the basic response properties, though not sufficient for some of their more subtle aspects.
Stiber
M
M
Department of Computer Science, The Hong Kong University of Science and Technology, Kowloon. stiber@cicada.berkeley.edu
Pakdaman
K
K
Vibert
J F
JF
Boussard
E
E
Segundo
J P
JP
Nomura
T
T
Sato
S
S
Doi
S
S
D000200:Action Potentials; D000818:Animals; D003400:Astacoidea; D001683:Biological Clocks / Q000502:physiology*; D008954:Models, Biological; D009474:Neurons / Q000502:physiology*; D017711:Nonlinear Dynamics