title: [Cases of american cutaneous leishmaniasis caused by Leishmania (Viannia) braziliensis in the towns of Cosmópolis and Indaiatuba-region of Campinas, in São Paulo, Brazil].
abstract: A study was carried out to identify Leishmania species involved in skin lesions of patients from Cosmópolis and Indaiatuba, State of São Paulo, Brazil. The epidemiological data of cutaneous leishmaniasis in two cities suggested a epidemic situation in 1994. The lesions were clinically characteristic of cutaneous leishmaniasis and five out six patients responded positively to Montenegro's intradermal test. The histopathology of skin lesions were characterized by two patterns: exudative-cellular reaction and exudative granulomatous reaction. The clinical and histopathological parameters suggested Leishmania (Viannia) braziliensis as the possible etiologic agent. In agreement, it was difficult to isolate and maintain the parasite in the laboratory. Characterization by in situ hybridization with kDNA amastigotes from lesions fragments confirmed that Leishmania (Viannia) braziliensis was the parasite responsible for the studied cutaneous lesions.
authors.affiliation: Departamento de Parasitologia do Instituto de Biologia e Anatomia Patológica da Faculdade de Ciências Médicas, Universidade Estadual de Campinas, Direção Regional de Saúde XII, Campinas, SP.
authors.forename: S
authors.initials: S
authors.lastname: Giorgio
authors.forename: E R
authors.initials: ER
authors.lastname: Deberaldini
authors.forename: R S
authors.initials: RS
authors.lastname: Pacheco
authors.forename: M Q
authors.initials: MQ
authors.lastname: Pires
authors.forename: E M
authors.initials: EM
authors.lastname: Zanotti-Magalhães
authors.forename: N
authors.initials: N
authors.lastname: Cordeiro
authors.forename: L A
authors.initials: LA
authors.lastname: Magalhães
authors.forename: M L
authors.initials: ML
authors.lastname: Cintra
authors.forename: N S
authors.initials: NS
authors.lastname: Guimarães
authors.forename: N M
authors.initials: NM
authors.lastname: Stedile
mesh_terms: D000328:Adult; D000818:Animals; D001938:Brazil; D005260:Female; D006801:Humans; D007892:Leishmania braziliensis / Q000302:isolation & purification*; D016773:Leishmaniasis, Cutaneous / Q000469:parasitology*; D008297:Male; D008875:Middle Aged
vernacular_title: Casos de leishmaniose tegumentar americana por Leishmania (Viannia) braziliensis nos Municípios de Cosmópolis e Indaiatuba-região de Campinas, Estado de São Paulo, Brasil.