Cutaneous lymphocytic vasculitis in acute myeloid leukaemia.
We report a 63-year-old woman who presented with an 8-week history of widespread indurated, purpuric lesions associated with weight loss of 7 kg and several episodes of epistaxis. A skin biopsy demonstrated a lymphocytic vasculitis with haemorrhage and parakeratosis. A blood film and bone marrow examination showed features of a myelodysplastic syndrome in transformation to acute myeloid leukaemia. Leucocytoclastic vasculitis and polyarteritis nodosa occur in association with acute myeloid leukaemia, but the association with lymphocytic vasculitis is new.
Farrell
A M
AM
Department of Dermatology, Charing Cross and Westminster Medical School, London, U.K.
Gooptu
C
C
Woodrow
D
D
Costello
C
C
Bunker
C B
CB
Cream
J J
JJ
D000208:Acute Disease; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications*; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000209:etiology* / Q000473:pathology; D017445:Skin Diseases, Vascular / Q000209:etiology* / Q000473:pathology; D014657:Vasculitis / Q000209:etiology* / Q000473:pathology