title: Choroidal melanoma in an African-American albino.
abstract: OBJECTIVE
  To report the rare occurrence of choroidal melanoma in an African-American albino.
  
  
  METHODS
  A 68-year-old African-American man with oculocutaneous albinism developed an amelanotic choroidal mass in his left eye. A transvitreal fine-needle aspiration biopsy was performed to confirm the diagnosis, and the patient was treated with iodine 125 plaque radiotherapy.
  
  
  RESULTS
  The cytology of the needle biopsy showed spindle cells with nuclear atypia and prominent nucleoli. The cells showed positive immunoreactivity for HMB-45, supporting the diagnosis of choroidal melanoma.
  
  
  CONCLUSIONS
  To our knowledge, this is the first reported case of a choroidal melanoma occurring in an African-American albino.
authors.affiliation: Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA.
authors.forename: S
authors.initials: S
authors.lastname: Kheterpal
authors.forename: J A
authors.initials: JA
authors.lastname: Shields
authors.forename: C L
authors.initials: CL
authors.lastname: Shields
authors.forename: P
authors.initials: P
authors.lastname: De Potter
authors.forename: H
authors.initials: H
authors.lastname: Ehya
authors.forename: K Y
authors.initials: KY
authors.lastname: Eng
mesh_terms: D001741:Black or African American; D000368:Aged; D016115:Albinism, Oculocutaneous / Q000150:complications* / Q000473:pathology; D001918:Brachytherapy; D002830:Choroid Neoplasms / Q000150:complications* / Q000473:pathology / Q000532:radiotherapy; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D008545:Melanoma / Q000150:complications* / Q000473:pathology / Q000532:radiotherapy
chemical_list: D007457:Iodine Radioisotopes