The vasculature of the peripheral portion of the human eighth cranial nerve.
The vasculature of the peripheral portion of the human eighth cranial nerve (VIIIN) was investigated by light and transmission electron microscopy. Arterioles and venules running longitudinally around the VIIIN formed the extrinsic vascular system. The anatomical relationship between these extrinsic vessels and the VIIIN sheath was similar to that between blood vessels on the surface of the brain and the pia mater. In the endoneurium, postcapillary venules and large capillaries were sparsely distributed and longitudinally arranged, and these microvessels formed the intrinsic microvascular system, which was supported by the extrinsic vascular system via anastomosing vessels. The ultrastructural features of the internal auditory artery and its main branches were the same as those of other intracranial arteries. Ultrastructural study also revealed myo-endothelial junctions in anastomosing arterioles, and endothelio-pericytic junctions in extrinsic and anastomosing venules. Microvascular endothelial cells were connected by tight junctions in both the vestibular ganglion and the rest of the VIIIN. These features of the vasculature were considered to be effective for maintenance of the endoneurial fluid and regulation of the circulation in the peripheral portion of the human VIIIN.
Matsunaga
T
T
Department of Otolaryngology, School of Medicine, Keio University, Tokyo, Japan. matsunag@mail.upenn.edu
Kanzaki
J
J
Hosoda
Y
Y
D000293:Adolescent; D000328:Adult; D000368:Aged; D001160:Arterioles / Q000648:ultrastructure*; D001163:Arteriovenous Anastomosis / Q000378:metabolism / Q000648:ultrastructure; D002196:Capillaries / Q000648:ultrastructure*; D002648:Child; D004730:Endothelium, Vascular / Q000166:cytology / Q000648:ultrastructure*; D005260:Female; D017629:Gap Junctions; D006801:Humans; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009442:Neurilemmoma / Q000601:surgery; D013136:Spiral Ganglion / Q000378:metabolism / Q000648:ultrastructure; D013194:Staining and Labeling; D014699:Venules / Q000648:ultrastructure*; D000159:Vestibulocochlear Nerve / Q000098:blood supply* / Q000648:ultrastructure