[The DNA-comet method for individual cells. The principle and use of the method].
The DNA comet assay allows to evaluate the damage in genomes of individual cells. This article summaries the literary evidence and the author's experience in development and application of the technique. Principles of the method are reviewed in addition to protocols for neutral and alkaline conditions; examples of application of the method are given.
Tronov
V A
VA
Pelevina
I I
II
D000818:Animals; D003584:Cytological Techniques / Q000295:instrumentation; D004247:DNA / Q000032:analysis* / Q000187:drug effects / Q000528:radiation effects; D004249:DNA Damage; D004260:DNA Repair; D004586:Electrophoresis / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D009152:Mutagenicity Tests / Q000295:instrumentation / Q000379:methods
D004247:DNA
Metod DNK-komet individual'nykh kletok. Printsip i primenenie metoda.