title: High and low density water and resting, active and transformed cells.
abstract: Resting and active states of cells are described in terms of the expectation, derived from experiments with aqueous polymers, that they contain two modified forms of water: high density, reactive, fluid water and low density, inert, viscous water. Low density water predominates in a resting cell and is converted to high density water in an active cell. It is proposed that switching from one state to another is an integral part of cellular function. When this ability is lost cells are transformed either to a state of rigor or to a hyperactive state in which they no longer depend upon external signals.
authors.affiliation: Department of Medicine, University of Auckland Faculty of Medicine and Health Science, New Zealand.
authors.forename: P M
authors.initials: PM
authors.lastname: Wiggins
mesh_terms: D001704:Biopolymers / Q000737:chemistry / Q000378:metabolism; D002471:Cell Transformation, Neoplastic; D002477:Cells / Q000378:metabolism*; D003593:Cytoplasm / Q000737:chemistry / Q000378:metabolism; D005782:Gels; D006860:Hydrogen Bonding; D007399:Interphase; D017136:Ion Transport; D008954:Models, Biological; D009995:Osmosis; D014783:Viscosity; D014867:Water / Q000737:chemistry / Q000378:metabolism*
chemical_list: D001704:Biopolymers; D005782:Gels; D014867:Water