title: Discordant technetium-99m-MIBI and technetium-99m-HMPAO uptake of recurrent occipital meningioma on brain SPECT images.
abstract: Technetium-99m-HMPAO and 99mTc-MIBI brain SPECT, MRI, CT and cerebral angiogram were studied in a patient with recurrent occipital meningioma. MRI and CT of the head showed right cerebral hemispheric tumor masses involving parasagittal, temporal and parietoccipital areas. The angiograms showed an intense vascular tumor blush in recurrent mass lesions supplied by the following arteries: the meningeal branch of the right external carotid artery, the right middle cerebral artery, the right anterior cerebral artery and the right posterior cerebral artery. Although demonstrable 99mTc-MIBI lesions mass exactly corresponded to CT and MRI (T-1) findings, mass lesions exhibited a mismatch between 99mTc-MIBI (increased uptake) and 99mTc-HMPAO (absent uptake) brain SPECT images. Technetium-99m-MIBI images, rather than 99mTc-HMPAO brain SPECT, resulted in the correct pathological diagnosis of recurrent meningioma.
authors.affiliation: Nuclear Medicine Service, Veterans Affairs Medical Center, Lexington, KY 40511, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Shih
authors.forename: J K
authors.initials: JK
authors.lastname: Lee
authors.forename: P
authors.initials: P
authors.lastname: Milan
mesh_terms: D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D002560:Cerebrovascular Circulation / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging*; D008579:Meningioma / Q000175:diagnosis / Q000000981:diagnostic imaging*; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000000981:diagnostic imaging*; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D017256:Technetium Tc 99m Sestamibi