Engineering pathways in Escherichia coli for the synthesis of morphine alkaloid analgesics and antitussives.
Hailes
A M
AM
Institute of Biotechnology, University of Cambridge, United Kingdom.
French
C E
CE
Rathbone
D A
DA
Bruce
N C
NC
D000429:Alcohol Oxidoreductases / Q000235:genetics*; D001426:Bacterial Proteins; D001711:Biotransformation; D003001:Cloning, Molecular; D003061:Codeine / Q000378:metabolism*; D004926:Escherichia coli; D006853:Hydrocodone; D004091:Hydromorphone; D009020:Morphine / Q000378:metabolism*; D010088:Oxidoreductases / Q000235:genetics*; D010957:Plasmids; D016958:Pseudomonas putida / Q000201:enzymology / Q000235:genetics
D001426:Bacterial Proteins; D006853:Hydrocodone; D009020:Morphine; D010088:Oxidoreductases; D000429:Alcohol Oxidoreductases; C045221:morphine 6-dehydrogenase; C087820:morphinone reductase; D004091:Hydromorphone; D003061:Codeine