Cestocidal activity of Acacia auriculiformis.
The cestocidal activity of Acacia auriculiformis was evaluated using rats each harbouring a single adult worm of Hymenolepis diminuta. The ethanol extract (300 mg/kg/day) and the saponins (200 mg/kg/day) obtained from the funicles of A. auriculiformis, were administered orally to two groups each of 10 rats, respectively, on day 20 after oral inoculation with a single cysticercoid of H. diminuta. Adult worms were expelled within 5 days from rats treated with the ethanol extract and within 3 days from those treated with saponins. No appreciable side effects were observed in the treated rats.
Ghosh
N K
NK
Department of Zoology, Visva-Bharati University, West Bengal, India.
Babu
S P
SP
Sukul
N C
NC
Ito
A
A
D000045:Acacia / Q000737:chemistry*; D000284:Administration, Oral; D000818:Animals; D000923:Anticestodal Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D005243:Feces / Q000469:parasitology; D006925:Hymenolepiasis / Q000188:drug therapy*; D006926:Hymenolepis / Q000187:drug effects; D008297:Male; D010270:Parasite Egg Count; D010936:Plant Extracts / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D051381:Rats; D012503:Saponins / Q000494:pharmacology / Q000627:therapeutic use*
D000923:Anticestodal Agents; D010936:Plant Extracts; D012503:Saponins