title: [Role of bronchoalveolar lavage and transbronchial biopsy in the diagnosis of pneumonia in patients with organ transplantation].
abstract: Pneumonia in patients with organ transplantation constitutes a very frequent cause of mortality, as a result precocious aetiologic diagnosis is indispensable. The bronchoscopic techniques, bronchoalveolar lavage (BAL) and transbronchial biopsy (TBB), constitute fundamental procedures for these diagnoses. We begin this study with the aim of evaluating the profitability obtained with these procedures. 36 bronchoscopies were performed on 29 patients with organ transplantation, in all of them we realized BAL and in 20 TBB. We confirm the presence of pneumonia in 30 (in 15 of them we had performed TBB), the BAL was diagnostic in 20 cases (66.6%) and the TBB in 7 (46.6%). With both, BAL and TBB, we obtained a sensitivity of 80% and a specificity of 75%. We isolated 10 bacteria, 8 Citomegalovirus (CMV), 6 Pneumocystis carinii and 2 Aspergillus fumigatus. The BAL and the TBB contributed significantly in the aetiologic diagnosis of pneumonia in patients with organ transplantation, consequently we consider them basic tools in the management of these infections.
authors.affiliation: Servicio de Neumología, Hospital General Universitario Gregorio Marañón, Madrid.
authors.forename: A
authors.initials: A
authors.lastname: Arnedillo Muñoz
authors.forename: M E
authors.initials: ME
authors.lastname: Lopez Moya
authors.forename: P
authors.initials: P
authors.lastname: de Lucas Ramos
authors.forename: L
authors.initials: L
authors.lastname: Puente Maestu
authors.forename: M J
authors.initials: MJ
authors.lastname: Sanchez Juanes
authors.forename: J M
authors.initials: JM
authors.lastname: Rodriguez Gonzalez-Moro
authors.forename: J
authors.initials: J
authors.lastname: Garcia de Pedro
authors.forename: M C
authors.initials: MC
authors.lastname: Rodriguez de Guzman
mesh_terms: D000328:Adult; D001706:Biopsy / Q000379:methods; D001980:Bronchi; D018893:Bronchoalveolar Lavage; D001999:Bronchoscopy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016377:Organ Transplantation; D011014:Pneumonia / Q000175:diagnosis* / Q000382:microbiology; D011446:Prospective Studies; D012680:Sensitivity and Specificity
vernacular_title: Papel del lavado broncoalveolar y la biopsia transbronquial en el diagnóstico de neumonías en pacientes portadores de trasplante de órganos.