Biotypes of oral Candida albicans isolates in a Tanzanian child population.
Although biotypes of Candida albicans from adult populations, especially in the West, have been described, there are no data either from a child population, or from the African continent. Hence a total of 200 oral C. albicans isolates from Tanzanian children aged 6-24 months were biotyped using two commercially available API micromethod kit systems and a boric acid resistance test. The predominant biotypes, which comprised two thirds of the organisms isolated, were J1S (19.5%), A1S (16.0%), J1R (14.5%), A1R (9.5%) and P1R (7.5%). In total, 16 new biotypes comprising 44 (22%) isolates which have not hitherto been described were found in this Tanzanian population and, of these, the P1R biotype predominated with 15 (7.5%) isolates. There was no significant association between predominant biotypes (with clusters > or = 15 isolates) and age, gender, breast feeding and malnutrition. These data indicate that the biotype profile of C. albicans isolates may differ in paediatric and adult populations, and/or global distribution of various subtypes of this common opportunistic pathogen.
Matee
M I
MI
Department of Microbiology and Immunology, Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania.
Samaranayake
L P
LP
Scheutz
F
F
Simon
E
E
Lyamuya
E F
EF
Mwinula
J
J
D002176:Candida albicans / Q000145:classification* / Q000302:isolation & purification; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D009061:Mouth Mucosa / Q000382:microbiology*; D016533:Mycological Typing Techniques; D015203:Reproducibility of Results; D013636:Tanzania; D014059:Tongue / Q000382:microbiology*