title: Effect of prenatal aluminium lactate exposure on conditioned taste aversion and passive avoidance task in the rat.
abstract: Pregnant SPRD rats were injected s.c. daily with 2.45, 4.9 and 9.8 mg kg-1 aluminium lactate or distilled water on gestational days 7-15. Gestational aluminium treatment had no effect either on litter size or the body weight of pups on postnatal day 1 but it decreased postnatal weight gain resulting in significantly lower body weight at weaning (postnatal day 22). It had no effect on the acquisition of a conditioned taste aversion, but in a passive avoidance task the learning ability of pups of dams given the top dose of aluminium was impaired.
authors.affiliation: Eötvös University, Department of Comparative Physiology, Budapest, Hungary.
authors.forename: Z
authors.initials: Z
authors.lastname: Gonda
authors.forename: K
authors.initials: K
authors.lastname: Lehotzky
mesh_terms: D000535:Aluminum / Q000633:toxicity*; D017607:Aluminum Compounds / Q000633:toxicity*; D000818:Animals; D001348:Aversive Therapy; D001362:Avoidance Learning / Q000187:drug effects*; D003213:Conditioning, Psychological; D005260:Female; D007773:Lactates / Q000633:toxicity*; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D051381:Rats; D011919:Rats, Inbred Strains; D013649:Taste / Q000187:drug effects*
chemical_list: D017607:Aluminum Compounds; D007773:Lactates; D000535:Aluminum; C104223:aluminum lactate