title: Selection of multiple resistance in Salmonella enteritidis during treatment with ciprofloxacin.
abstract: We report on a strain of Salmonella enteritidis which was found to be resistant to both ciprofloxacin and beta-lactams and chloramphenicol in a patient treated with ciprofloxacin for a splenic abscess. We conclude that in invasive infections such as a splenic abscess caused by Salmonella, early surgical intervention is important. Multiple-drug-resistant strains of Salmonella may be selected by treatment with ciprofloxacin alone.
authors.affiliation: Department of Clinical Microbiology, Odense University Hospital, Denmark.
authors.forename: C
authors.initials: C
authors.lastname: Pers
authors.forename: P
authors.initials: P
authors.lastname: Søgaard
authors.forename: L
authors.initials: L
authors.lastname: Pallesen
mesh_terms: D000038:Abscess / Q000188:drug therapy* / Q000382:microbiology; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002701:Chloramphenicol / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use*; D018432:Drug Resistance, Multiple; D006801:Humans; D007769:Lactams; D008297:Male; D012480:Salmonella Infections / Q000188:drug therapy* / Q000382:microbiology; D012477:Salmonella enteritidis / Q000302:isolation & purification*; D013154:Spleen / Q000382:microbiology; D013158:Splenic Diseases / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D007769:Lactams; D002939:Ciprofloxacin; D002701:Chloramphenicol