Quinoxaline-2-carboxylic acid (QCA) in swine liver and muscle.
The concentration of quinoxaline-2-carboxylic acid (QCA) determined by HPLC after alkaline hydrolysis of liver and muscle of swine, ranged from < 3 ng/g to 45.3 ng/g in liver, and from < 3 ng/g to 10.8 ng/g in muscle samples. After the 77th day of therapy QCA was found in samples of liver (9.7 ng/g). Recoveries obtained for both liver and muscle were 70% at 5 ng/g, 77% and 75% respectively at 10 ng/g, and 90% for both liver and muscle at 30 ng/g. This experiment was performed within the frame of the National Monitoring Programme of Residues in Animal Tissues in the Republic of Croatia.
Rutalj
M
M
Veterinary Institute Kriźevci, Croatia.
Bazulić
D
D
Sapunar-Postruznik
J
J
Zivković
J
J
Ljubicić
I
I
D000818:Animals; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002218:Carbadox / Q000627:therapeutic use*; D002851:Chromatography, High Pressure Liquid; D008099:Liver / Q000378:metabolism*; D009132:Muscles / Q000378:metabolism*; D011810:Quinoxalines / Q000032:analysis / Q000493:pharmacokinetics*; D013552:Swine
D000890:Anti-Infective Agents; D011810:Quinoxalines; D002218:Carbadox; C042218:quinoxaline-2-carboxylic acid