Hepatic haemangioendothelioma presenting with early heart failure in a newborn: treatment with hepatic artery embolization and interferon.
We report our management of a newborn presenting in utero with congestive heart failure secondary to a giant hepatic haemangioendothelioma. Control of heart failure was achieved by transcatheter hepatic artery embolization, and rapid regression of the tumor was observed after a course of alpha 1 interferon. The combination of hepatic artery embolization and interferon may be a useful approach in the management of this rare, potentially fatal condition.
Fok
T F
TF
Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong.
Chan
M S
MS
Metreweli
C
C
Ng
P C
PC
Yeung
C K
CK
Li
A K
AK
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D004621:Embolization, Therapeutic; D006333:Heart Failure / Q000209:etiology / Q000628:therapy*; D006390:Hemangioendothelioma / Q000150:complications / Q000628:therapy*; D006499:Hepatic Artery; D006801:Humans; D007231:Infant, Newborn; D016898:Interferon-alpha / Q000627:therapeutic use*; D008113:Liver Neoplasms / Q000150:complications / Q000628:therapy*; D008297:Male
D000970:Antineoplastic Agents; D016898:Interferon-alpha