The oro-facial manifestations of trisomy 8 mosaicism: a case report.
Trisomy 8 mosaicism is a relatively common autosomal chromosomal disorder characterized by features such as mental retardation, characteristic facies, skeletal abnormalities and congenital heart disease. The case of a 4-year-old boy is described with particular reference to the oro-facial manifestations, which included cleft palate, pronounced anterior open bite, complete reserved unilateral buccal cross-bite, slightly increased width of alveolar processes, and gingival enlargement.
Henderson
N J
NJ
Department of Child Dental Health, University of Bristol, England.
Crawford
P J
PJ
D002675:Child, Preschool; D002898:Chromosomes, Human, Pair 8; D002972:Cleft Palate / Q000235:genetics; D005885:Gingival Hyperplasia / Q000235:genetics; D006801:Humans; D008297:Male; D008310:Malocclusion / Q000235:genetics; D009030:Mosaicism / Q000473:pathology; D009056:Mouth Abnormalities / Q000235:genetics*; D014314:Trisomy / Q000473:pathology