title: Penicillin-resistant Streptococcus pneumoniae in a Jamaican patient with homozygous sickle-cell disease.
abstract: Penicillin prophylaxis against infection by Streptococcus pneumoniae is now routine in young children with homozygous sickle-cell (SS) disease and the emergence of penicillin-resistant strains is a serious clinical concern. The first death associated with such resistance in a Jamaican child with SS disease is reported.
authors.affiliation: Dept. of Microbiology, University of the West Indies, Kingston, Jamaica.
authors.forename: K J
authors.initials: KJ
authors.lastname: Wierenga
authors.forename: F
authors.initials: F
authors.lastname: Moosdeen
authors.forename: S
authors.initials: S
authors.lastname: Thomas
authors.forename: G R
authors.initials: GR
authors.lastname: Serjeant
mesh_terms: D000755:Anemia, Sickle Cell / Q000150:complications*; D016470:Bacteremia / Q000150:complications*; D002648:Child; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007563:Jamaica; D010403:Penicillin Resistance; D011008:Pneumococcal Infections / Q000150:complications*; D013296:Streptococcus pneumoniae