Genetic heterogeneity of HIV type 1 in Russia: identification of H variants and relationship with epidemiological data.
HIV-genetic subtypes were analyzed in 130 subjects from the Russian Federation, by the HMA technique. Six subtypes were identified in heterosexuals, including A, B, C, D, G, and H; however, homosexual men were infected predominantly with the B subtype (33 of 35). The subtype A isolates were found in population of intravenous drug users. HMA successfully identifies 128/130 DNA samples; the phylogenetic analysis of the V1/V5 gp120 encoding region derived from another two samples demonstrated that these isolate belong to subtype H.
Bobkov
A
A
D.I. Ivanovsky Institute of Virology, Moscow, Russia.
Cheingsong-Popov
R
R
Selimova
L
L
Kazennova
E
E
Karasyova
N
N
Kravchenko
A
A
Ladnaya
N
N
Pokrovsky
V
V
Weber
J
J
D000595:Amino Acid Sequence; D001483:Base Sequence; D004279:DNA, Viral; D005260:Female; D014644:Genetic Variation; D015699:HIV Envelope Protein gp120 / Q000235:genetics*; D015658:HIV Infections / Q000453:epidemiology / Q000821:virology*; D015497:HIV-1 / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D007223:Infant; D008297:Male; D008969:Molecular Sequence Data; D010802:Phylogeny; D012426:Russia / Q000453:epidemiology; D012689:Sequence Homology, Nucleic Acid
D004279:DNA, Viral; D015699:HIV Envelope Protein gp120