The utility of submitting fibroepithelial polyps for histological examination.
BACKGROUND
The fibroepithelial polyp (FEP) is a common cutaneous lesion that is often removed for medical or cosmetic reasons. We examined the utility of submitting clinically diagnosed FEPs for routine microscopic examination.


METHODS
We reviewed 11500 consecutive cutaneous pathology reports. Materials submitted with the clinical diagnosis of FEP or a synonym were reviewed and the histopathologic slides were examined. A comparison group of specimens submitted with the clinical diagnosis of melanocytic nevus was reviewed.


METHODS
The biopsy reports were generated at a regional non-hospital-based dermatopathology laboratory providing service to physicians (dermatologists and nondermatologists) practicing ambulatory medicine predominantly within a 4-state region (Ind, Ky, Tenn, and WVa).


RESULTS
Of 1335 clinical specimens submitted as FEPs, there were 5 malignant tumors. In the comparison group of 697 clinically diagnosed melanocytic nevi, there were 6 malignant tumors. In comparison with clinically diagnosed melanocytic nevi, the likelihood that a lesion clinically diagnosed as FEP would be a malignant tumor on histological examination is very low (relative risk, 0.4). None of the lesions clinically diagnosed as FEPs by dermatologists proved to be malignant.


CONCLUSIONS
Our data suggest there is an extremely low prevalence of malignancy in lesions clinically diagnosed as FEPs. We conclude that cutaneous lesions diagnosed as typical FEPs by dermatologists need not be submitted for microscopic examination.
Eads
T J
TJ
Department of Dermatology, Indiana University Medical Center, Indianapolis, USA.
Chuang
T Y
TY
Fabré
V C
VC
Farmer
E R
ER
Hood
A F
AF
D000553:Ambulatory Care; D002278:Carcinoma in Situ / Q000473:pathology; D002280:Basal Cell Carcinoma / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D003880:Dermatology; D003937:Diagnosis, Differential; D006652:Histological Techniques; D006801:Humans; D006965:Hyperplasia; D007196:Indiana; D007629:Kentucky; D008853:Microscopy; D009508:Nevus, Pigmented / Q000473:pathology; D011127:Polyps / Q000473:pathology*; D015995:Prevalence; D012307:Risk Factors; D012878:Skin Neoplasms / Q000473:pathology*; D013714:Tennessee; D014903:West Virginia