title: Fuzzy logic control of mechanical ventilation during anaesthesia.
abstract: We have examined a new approach, using fuzzy logic, to the closed-loop feedback control of mechanical ventilation during general anaesthesia. This control system automatically adjusts ventilatory frequency (f) and tidal volume (VT) in order to achieve and maintain the end-tidal carbon dioxide fraction (FE'CO2) at a desired level (set-point). The controller attempts to minimize the deviation of both f and VT per kg body weight from 10 bpm and 10 ml kg-1, respectively, and to maintain the plateau airway pressure within suitable limits. In 30 patients, undergoing various surgical procedures, the fuzzy control mode was compared with human ventilation control. For a set-point of FE'CO2 = 4.5 vol% and during measurement periods of 20 min, accuracy, stability and breathing pattern did not differ significantly between fuzzy logic and manual ventilation control. After step-changes in the set-point of FE'CO2 from 4.5 to 5.5 vol% and vice versa, overshoot and rise time did not differ significantly between the two control modes. We conclude that to achieve and maintain a desired FE'CO2 during routine anaesthesia, fuzzy logic feedback control of mechanical ventilation is a reliable and safe mode of control.
authors.affiliation: Institute of Anaesthesiology and Intensive Care, University Hospital, Bern, Switzerland.
authors.forename: J
authors.initials: J
authors.lastname: Schäublin
authors.forename: M
authors.initials: M
authors.lastname: Derighetti
authors.forename: P
authors.initials: P
authors.lastname: Feigenwinter
authors.forename: S
authors.initials: S
authors.lastname: Petersen-Felix
authors.forename: A M
authors.initials: AM
authors.lastname: Zbinden
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000768:Anesthesia, General; D002245:Carbon Dioxide / Q000097:blood / Q000502:physiology*; D002648:Child; D003198:Computer Simulation; D005246:Feedback; D005260:Female; D017143:Fuzzy Logic; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010313:Partial Pressure; D012121:Respiration, Artificial / Q000379:methods*
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen