title: [Hypergammaglobulinemia D and familial urticaria in children].
abstract: OBJECTIVE
  Recall the main elements suggesting the diagnosis of hyperimmunoglobulinemia D based on a family case of chronic urticaria.
  
  
  METHODS
  A boy and his mother presented the same signs of urticaria, fever and joint pain. Laboratory results showed an inflammatory syndrome in both. In the child, the first manifestations occurred during the age of one year. Hyperimmunoglobulinemia D was confirmed by persistently high serum levels.
  
  
  CONCLUSIONS
  The diagnosis of hyperimmunoglobuliemia D can be entertained in a child in a family with chronic urticaria. Fever, joint pain, digestive disorders and enlarged lymph nodes are suggestive and the diagnosis is confirmed by a clear elevation of serum IgD.
authors.affiliation: Service de Pédiatrie générale, Hôpital Bicêtre, Le Kremlin Bicêtre.
authors.forename: B
authors.initials: B
authors.lastname: Bader-Meunier
authors.forename: P Y
authors.initials: PY
authors.lastname: Venencie
authors.forename: A
authors.initials: A
authors.lastname: Vieillefond
authors.forename: P
authors.initials: P
authors.lastname: Le Touze
authors.forename: J P
authors.initials: JP
authors.lastname: Dommergues
mesh_terms: D018771:Arthralgia / Q000209:etiology; D002675:Child, Preschool; D005334:Fever / Q000209:etiology; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D007072:Immunoglobulin D; D008297:Male; D012008:Recurrence; D014581:Urticaria / Q000150:complications / Q000235:genetics* / Q000276:immunology
chemical_list: D007072:Immunoglobulin D
vernacular_title: Hyper-immunoglobulinémie D et urticaire familiale de l'enfant.