Sucralfate and Helicobacter pylori.
Sucralfate enhances the eradication rate of Helicobacter pylori when administered with antibiotics. Sucralfate acts on H. pylori through mucus gel. Whether sucralfate exerts its anti-ulcer action through the eradication of H. pylori is still controversial. As sucralfate itself is an effective, well-tolerated and cost-effective anti-ulcer agent, its mechanisms of action should be investigated further.
Terano
A
A
Second Department of Medicine, Dokkyo University, School of Medicine, Tochigi, Japan.
Shimada
T
T
Hiraishi
H
H
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004381:Duodenal Ulcer / Q000188:drug therapy / Q000382:microbiology; D016481:Helicobacter Infections / Q000188:drug therapy*; D016480:Helicobacter pylori / Q000187:drug effects; D006801:Humans; D013392:Sucralfate / Q000627:therapeutic use*
D000900:Anti-Bacterial Agents; D000897:Anti-Ulcer Agents; D013392:Sucralfate