Toxic epidermal necrolysis.
Toxic epidermal necrolysis (TEN) is a rare, drug-induced, life-threatening syndrome with widespread epidermal loss and mucosal erosions. The classification, pathophysiology, clinical features and treatment are discussed in this review. Prognosis has improved as admission to a burns unit and early treatment of infection has become standard management. The role of corticosteroids in treatment is still controversial.
Weightman
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Department of Dermatology, Queen Elizabeth Hospital, Woodville, Australia.
D006801:Humans; D011379:Prognosis; D013262:Stevens-Johnson Syndrome / Q000209:etiology / Q000503:physiopathology / Q000628:therapy