Systemic lupus erythematosus in males. A study of 107 Latin American patients.
Clinical and laboratory features were analyzed in 107 Latin American male patients with systemic lupus erythematosus (SLE) who were compared with a group of 1,209 Latin American female patients with SLE to determine the presence of gender-associated differences. Males had an increased prevalence of renal disease, vascular thrombosis, and the presence of anti-dsDNA antibodies, as well as the use of moderate to high doses of corticosteroids, compared with female SLE patients. Although there was no difference in mortality from all causes, SLE-related mortality was higher in the male group. All these findings are consistent with a more severe disease in Latin American males than in female patients from the same region.
Molina
J F
JF
Department of Internal Medicine, Instituto Nacional de la Nutrición Salvador Zubirán, México City, México.
Drenkard
C
C
Molina
J
J
Cardiel
M H
MH
Uribe
O
O
Anaya
J M
JM
Gomez
L J
LJ
Felipe
O
O
Ramirez
L A
LA
Alarcon-Segovia
D
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D002423:Cause of Death; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007843:Latin America; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000401:mortality / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D012727:Sex Characteristics