title: Toward further reducing wound infections in cardiac operations.
abstract: BACKGROUND
  Serious wound infections such as mediastinitis still occur at a rate of 0.8% to 2.0%, according to the most recently published cardiac operative series.
  
  
  METHODS
  Data from careful surveillance for infection have been collected prospectively during a 4.5-year period on 1,717 patients who underwent cardiac operations performed under direct ultraviolet C radiation.
  
  
  RESULTS
  The rate for mediastinitis was 0.23%, and for deep incisional infection without mediastinitis, 0.12%; these rates are significantly lower than those for eight of nine of the most recently published cardiac series. When our infection rates were stratified using the National Nosocomial Infection Surveillance risk index, they were also significantly lower in the most important risk categories than the corresponding stratified rates collected from the participating hospitals of the Centers for Disease Control and Prevention National Nosocomial Infection Surveillance system.
  
  
  CONCLUSIONS
  Though we lack the proof that only a large, randomized study might provide, certainly, one possible explanation for our lower wound infection rate was the use of bactericidal ultraviolet C radiation during operation. This is a simple and effective means of minimizing operating room airborne bacteria as one possible source of these infections.
authors.affiliation: Department of Cardiovascular Surgery, Watson Clinic, Lakeland, Florida 33804-5000, USA.
authors.forename: I W
authors.initials: IW
authors.lastname: Brown
authors.forename: G F
authors.initials: GF
authors.lastname: Moor
authors.forename: B W
authors.initials: BW
authors.lastname: Hummel
authors.forename: W G
authors.initials: WG
authors.lastname: Marshall
authors.forename: J P
authors.initials: JP
authors.lastname: Collins
mesh_terms: D000368:Aged; D000391:Air Microbiology; D001419:Bacteria / Q000528:radiation effects; D006348:Cardiac Surgical Procedures; D005260:Female; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000209:etiology*; D008875:Middle Aged; D009873:Operating Rooms; D011446:Prospective Studies; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000517:prevention & control*; D014466:Ultraviolet Rays