Experimental measure of the tensile strength of biological sealant-collagen association after hepatectomy in dogs.
Fibrin sealants are commonly used in liver surgery. The aim of this study was to test the adhesive properties of a biological sealant-collagen bonding, using an experimental model. After hepatectomy in dogs, we measured the rupture stress point of a fibrin clot on the liver cross-section. The tensile strength was 0.28 N, 5 times higher than the force of arterial pressure in a 2-mm-diameter vessel. These results indicate that the adhesion of fibrin sealants is effective to prevent hemorrhage from the liver cross-section after hepatectomy.
Scotté
M
M
Groupe de Biochimie et Physiopathologie Digestive et Nutritionnelle, Centre Hospitalier Universitaire, Rouen, France.
Dujardin
F
F
Amelot
A
A
Azema
P
P
Leblanc
I
I
Bouvier
P
P
Michot
F
F
Ténière
P
P
D000818:Animals; D003094:Collagen; D004285:Dogs; D015718:Fibrin Tissue Adhesive; D006498:Hepatectomy; D008297:Male; D013718:Tensile Strength
D015718:Fibrin Tissue Adhesive; D003094:Collagen