title: [Early detection of breast cancer in Navarra. Diagnostic approach in women sent to a referral hospital].
abstract: BACKGROUND
  Breast cancer screening programs represent an important increase in the number of patients to be evaluated and a higher proportion of subclinical lesions detected in reference hospitals. The authors' experience related to an early detection program initiated in Navarra, Spain (PDPCM) is herein presented.
  
  
  METHODS
  The diagnoses made in 319 women referred from the PDPCM to the authors' hospital for mammographic suspicion of malignancy were reviewed. Directed surgical biopsy was carried out in 89 women (27.9%) without previous cytologic study. Fine needle aspiration punction and cytology (FNAP-cytology) were performed as the first diagnostic test in 216 lesions (67.7%) 53 of which were palpable and 163 nonpalpable. Aggressive techniques were not indicated in 14 cases (4.4%).
  
  
  RESULTS
  A total of 136 carcinomas (42.6%) were diagnosed and benign lesions were find at biopsy in 112 (35.1%) women. The fifty-seven lesions (17.9%) which did not show malignancy on FNAP-cytology were not biopsied given the insufficient degree of suspicion. Only one false negative has appeared in this group from 27 to 48 months after the first consultation. The global diagnostic reliability was of 99.68%.
  
  
  CONCLUSIONS
  Directed surgical biopsy is the most reliable technique for the diagnosis of nonpalpable breast lesions in early stages and is always necessary when there is medium or high radiologic suspicion of malignancy. Fine needle aspiration puncture is a very useful technique to confirm malignancy and to avoid unnecessary biopsies in low suspicion lesions.
authors.affiliation: Servicio de Radiología, Hospital Virgen del Camino, Pamplona.
authors.forename: L
authors.initials: L
authors.lastname: Apesteguía Ciriza
authors.forename: A
authors.initials: A
authors.lastname: Osa Labrador
authors.forename: E
authors.initials: E
authors.lastname: Extramiana Cameno
authors.forename: C
authors.initials: C
authors.lastname: de Miguel Medina
authors.forename: B
authors.initials: B
authors.lastname: Reparaz Romero
authors.forename: F
authors.initials: F
authors.lastname: Domínguez Cunchillos
authors.forename: M
authors.initials: M
authors.lastname: Trujillo Ascani Aizcorbe Garralda
mesh_terms: D000328:Adult; D001706:Biopsy; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D012017:Referral and Consultation; D013030:Spain; D013997:Time Factors
vernacular_title: Detección precoz del cáncer de mama en Navarra. Conducta diagnóstica en las mujeres enviadas a un hospital de referencia.