title: [Heparin-induced thrombocytopenia].
abstract: Heparin induced thrombocytopenia (HIT) is the result of platelet activation and it is either nonimmunologically (type I) or immunologically mediated (type II). HIT is the most frequent drug induced immune thrombocytopenia. It is completely different from all other forms of immune thrombocytopenia, because it can be accompanied by serious thromboembolic complication because of its serious clinical consequences must be prompt and very intensive.
authors.affiliation: Oddĕlení klinické hematologie LF UK a FN, Hradec Králové.
authors.forename: P
authors.initials: P
authors.lastname: Dulícek
authors.forename: L
authors.initials: L
authors.lastname: Chrobák
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects*; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy
chemical_list: D000925:Anticoagulants; D006493:Heparin
vernacular_title: Trombocytopenie indukovaná heparinem.