title: Studies on psychopharmacological effects of Nelumbo nucifera Gaertn. rhizome extract.
abstract: Methanolic extract of rhizomes of Nelumbo nucifera (NNRE) was investigated for different psychopharmacological actions in rats and mice. The extract was found to cause reduction in spontaneous activity, decrease in exploratory behavioural pattern by the head dip and Y-maze test, reduction in muscle relaxant activity by rotarod, 30 degrees inclined screen and traction test and potentiated the pentobarbitone induced sleeping time in mice significantly.
authors.affiliation: Department of Pharmaceutical Technology, Faculty of Engineering and Technology, Jadavpur University, Calcutta, India.
authors.forename: P K
authors.initials: PK
authors.lastname: Mukherjee
authors.forename: K
authors.initials: K
authors.lastname: Saha
authors.forename: R
authors.initials: R
authors.lastname: Balasubramanian
authors.forename: M
authors.initials: M
authors.lastname: Pal
authors.forename: B P
authors.initials: BP
authors.lastname: Saha
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D004357:Drug Synergism; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D008297:Male; D051379:Mice; D009125:Muscle Relaxants, Central / Q000494:pharmacology; D010424:Pentobarbital / Q000494:pharmacology; D010946:Plants, Medicinal; D011619:Psychotropic Drugs / Q000494:pharmacology*; D051381:Rats; D012890:Sleep / Q000187:drug effects
chemical_list: D004365:Drugs, Chinese Herbal; D009125:Muscle Relaxants, Central; D011619:Psychotropic Drugs; D010424:Pentobarbital