[Comparative study of inactivated cultured vaccines against tick-borne encephalitis manufactured in Russia and in Austria by the "Immuno" firm].
Inactivated culture vaccine against tick-borne encephalitis (TBE) FSME-Immun-Inject produced in Austria ("Immuno") was compared to vaccine produced in the Institute of Poliomyelitis and viral encephalitis by immunological activity, safety, reactogenicity. In mice, no significant differences in protective activity of the vaccines were found when test-strains were diverse strains of TBE virus. Seroconversion in the sera from the vaccinated two times was not significantly different by the level of antibodies determined for both eastern and western serotypes of TBE virus.
Vorob'eva
M S
MS
Rasshchepkina
M N
MN
Ladyzhenskaia
I P
IP
Gorbunov
M A
MA
Pavlova
L I
LI
Bektimirov
T A
TA
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D001317:Austria; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology*; D004675:Encephalitis, Tick-Borne / Q000276:immunology / Q000517:prevention & control*; D006385:Hemagglutination Inhibition Tests; D007124:Immunoenzyme Techniques; D051379:Mice; D008807:Mice, Inbred BALB C; D012426:Russia; D014611:Vaccination; D015164:Vaccines, Inactivated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology; D014776:Virus Cultivation
D000914:Antibodies, Viral; D015164:Vaccines, Inactivated; D014765:Viral Vaccines
Sravnitel'noe izuchenie inaktivirovannykh kul'tural'nykh vaktsin protiv kleshchevogo 7entsefalita otechestvennogo proizvodstva i proizvodstva firmy "Immuno" (Avstriia).