title: Impact of pregnancy on non-metastatic breast cancer: a case control study.
abstract: The diagnosis of breast cancer during pregnancy remains uncommon and therefore leads to non-standardized management. We reviewed retrospectively 28 such women treated at this centre and compared them with age and stage matched controls. Differences in management and outcome were analysed for statistical significance. There was no significant difference in overall survival (P = 0.86) and relapse-free survival (P = 0.48) between the two groups. Chemotherapy after the first trimester of pregnancy carried no significant morbidity. Pregnancy does not appear to be an adverse prognostic factor for breast cancer.
authors.affiliation: King Faisal Specialist Hospital and Research Centre, Riyadh, Kingdom of Saudi Arabia.
authors.forename: A
authors.initials: A
authors.lastname: Ezzat
authors.forename: M A
authors.initials: MA
authors.lastname: Raja
authors.forename: J
authors.initials: J
authors.lastname: Berry
authors.forename: F E
authors.initials: FE
authors.lastname: Zwaan
authors.forename: A
authors.initials: A
authors.lastname: Jamshed
authors.forename: D
authors.initials: D
authors.lastname: Rhydderch
authors.forename: A
authors.initials: A
authors.lastname: Rostom
authors.forename: S
authors.initials: S
authors.lastname: Bazarbashi
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D016013:Likelihood Functions; D015999:Multivariate Analysis; D009367:Neoplasm Staging; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000401:mortality* / Q000473:pathology / Q000628:therapy; D016016:Proportional Hazards Models; D012044:Regression Analysis; D012189:Retrospective Studies; D016019:Survival Analysis