[Comparative study of 201Tl and 99mTc-MIBI in breast tumor].
A comparative study of 201Tl and 99mTc-MIBI was performed in 39 breast tumors. 201Tl scintigraphy was carried out in 24 breast tumors and 99mTc-MIBI scintigraphy in 15. The sensitivity of 201Tl for malignant tumors was 100% (22/22), but specificity was 0% (0/2). On 99mTc-MIBI scintigraphy, the sensitivity for the malignant tumors was 83.3% (10/12) and specificity was 100% (3/3). 99Tc-MIBI might be more useful for the diagnosis of breast tumors, because the tumor/background ratio of 99mTc-MIBI was significantly higher than that of 201Tl. In addition, 201Tl scintigraphy and 99mTc-MIBI scintigraphy showed the same degree of accuracy (93.3%) in diagnosis of lymph node reached. Moreover, when either US and 201Tl or 99mTc-MIBI scintigraphy was positive for lymph node metastasis, accuracy of detection of lymph node metastasis became 94.4%. A combined study of US and scintigraphy might improve the accuracy for diagnosis of lymph node metastasis.
Fukumitsu
N
N
Department of Radiology, Jikei University school of Medicine.
Tozaki
M
M
Uchiyama
M
M
Mori
Y
Y
Kawakami
K
K
Uchida
K
K
D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging*; D008875:Middle Aged; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon
D013794:Thallium Radioisotopes; D017256:Technetium Tc 99m Sestamibi