title: Zygotic lethal mutations with maternal effect phenotypes in Drosophila melanogaster. II. Loci on the second and third chromosomes identified by P-element-induced mutations.
abstract: Screens for zygotic lethal mutations that are associated with specific maternal effect lethal phenotypes have only been conducted for the X chromosome. To identify loci on the autosomes, which represent four-fifths of the Drosophila genome, we have used the autosomal "FLP-DFS" technique to screen a collection of 496 P element-induced mutations established by the Berkeley Drosophila Genome Project. We have identified 64 new loci whose gene products are required for proper egg formation or normal embryonic development.
authors.affiliation: Department of Genetics, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts 02115, USA. perrimon@rascal.med.harvard.edu
authors.forename: N
authors.initials: N
authors.lastname: Perrimon
authors.forename: A
authors.initials: A
authors.lastname: Lanjuin
authors.forename: C
authors.initials: C
authors.lastname: Arnold
authors.forename: E
authors.initials: E
authors.lastname: Noll
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D004251:DNA Transposable Elements / Q000235:genetics*; D004331:Drosophila melanogaster / Q000235:genetics*; D005821:Genetic Techniques; D009154:Mutation; D010641:Phenotype
chemical_list: D004251:DNA Transposable Elements