Fiber types of the lingual branch of the trigeminal nerve, chorda tympani, lingual-tonsillar and pharyngeal branches of the glossopharyngeal nerve, and superior laryngeal nerve and their relation to the cardiovascular responses in rats.
The effect of repetitive electrical stimulation at 50 Hz for 20 s of the lingual branch of the trigeminal nerve (LN), chorda tympani (CT), lingual-tonsillar (LT-IXth) and pharyngeal (PH-IXth) branches of the glossopharyngeal nerve, and superior laryngeal nerve (SLN) on the changes in arterial blood pressure (BP) and heart rate (HR) were investigated in anesthetized and paralyzed rats. The compound action potentials in these nerves were simultaneously recorded to know the relationships between the fiber types and the cardiovascular responses. In all nerves except the CT, repetitive electrical stimulation of the nerve elicited a tachycardia and an increase in BP. These cardiovascular responses were mainly related to the component-2 in the compound action potentials in respective nerves. The conduction velocities of the component-2 in the five nerves examined in the present experiment were between 9.5 and 17.0 m/s (mean, n = 4-7). Other components which have faster (component-1) or slower conduction velocities (component-3 and -4) than the component-2 were not likely to elicit the cardiovascular responses. These results suggest that nociceptive and taste fibers of A-delta fibers innervating the oral cavity and pharyngolaryngeal region largely contribute to the cardiovascular responses.
Hanamori
T
T
Department of Physiology, Miyazaki Medical College, Japan.
Kunitake
T
T
Kato
K
K
Kannan
H
H
D000818:Animals; D001794:Blood Pressure / Q000502:physiology*; D004558:Electric Stimulation; D005930:Glossopharyngeal Nerve / Q000502:physiology*; D006339:Heart Rate / Q000502:physiology*; D007823:Laryngeal Nerves / Q000502:physiology*; D009412:Nerve Fibers / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D014276:Trigeminal Nerve / Q000502:physiology*