Synthesis of allosamidin analogues.
Two new isomers of allosamidin and allosamizoline, and two dimeric allosamidin analogues have been synthesized. The new compounds have been tested for inhibition of insect chitinase and for toxicity to insect larvae.
Blattner
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Industrial Research Limited, Lower Hutt, New Zealand.
Furneaux
R H
RH
Lynch
G P
GP
D000117:Acetylglucosamine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D000818:Animals; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D002688:Chitinases / Q000037:antagonists & inhibitors; D004791:Enzyme Inhibitors; D007313:Insecta / Q000201:enzymology; D007306:Insecticides / Q000138:chemical synthesis / Q000633:toxicity; D007814:Larva / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D015394:Molecular Structure; D013329:Structure-Activity Relationship; D014312:Trisaccharides / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology
D004791:Enzyme Inhibitors; D007306:Insecticides; D014312:Trisaccharides; C054851:allosamidin; D002688:Chitinases; D000117:Acetylglucosamine