Prolonged local infusion of streptokinase in pulmonary artery thrombosis with nephrotic syndrome.
A child with nephrotic syndrome presenting with right heart failure and severe pulmonary hypertension due to pulmonary artery thrombus was treated with locally administered streptokinase infusion. Streptokinase infusion was continued for 8 days, eventually leading to complete dissolution of thrombus.
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Department of Paediatric Cardiology, Killingbeck Hospital, Leeds, West Yorkshire, UK.
Uzun
O
O
Blackburn
M E
ME
Gibbs
J L
JL
D000792:Angiography; D002675:Child, Preschool; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D006333:Heart Failure / Q000150:complications; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications; D007261:Infusions, Intra-Arterial; D009404:Nephrotic Syndrome / Q000150:complications* / Q000000981:diagnostic imaging; D011651:Pulmonary Artery; D013300:Streptokinase / Q000008:administration & dosage / Q000627:therapeutic use*; D013927:Thrombosis / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*
D005343:Fibrinolytic Agents; D013300:Streptokinase