title: Aortic valve replacement after aortic valvuloplasty for calcified aortic stenosis.
abstract: OBJECTIVE
  This study concerns patients who underwent one or several aortic balloon valvuloplasties at our institution and subsequently required cardiac surgery, either on an emergency basis after aortic valvuloplasty or due to the development of aortic stenosis.
  
  
  METHODS
  Between February 1987 and December 1993, 137 patients (73 male, 64 female, mean age 72 +/- 9 years) underwent aortic valve replacement for calcified aortic stenosis after several percutaneous balloon aortic valvuloplasties. Thirty-one patients were in NYHA stage II, 70 in stage III and 36 in stage IV. Seventy patients had angina (23 stage I or II, 47 stage III or IV) and 24 patients presented syncope or lipothymia. Twenty-three percent had at least two of these three symptoms. The indications for balloon dilatation were non-definitive surgical contraindication or high surgical risk (73), personal choice (49), refusal of surgery (9) and emergency (5:2 massive aortic regurgitation, 1 left ventricle perforation, 1 cardiogenic shock, 1 endocarditis in cardiogenic shock). Seven patients received preoperative aortic valvuloplasty due to a very high operative risk. The average time between dilatation and surgery was 472 days and there was clinical improvement for an average period of 261 days. The aortic valve replacements consisted of 58 mechanical prostheses and 79 xenografts with 22 concomitant procedures.
  
  
  RESULTS
  Operative mortality was eight patients (5.8%). During the follow-up (17.4 +/- 9.2 months), four patients died (3.6%), 91.2% of the patients were in class I and II and 95% were without angina. The actuarial survival rate was 90.5 +/- 6.6% including hospital mortality.
  
  
  CONCLUSIONS
  Both our experience and the literature show that balloon aortic valvuloplasty is followed by an immediate improvement in hemodynamic status with a decrease in valve gradient and an increase in valve area. However, the hemodynamic benefit is typically short-lived with a very high restenosis rate. Balloon aortic valvuloplasty is not an alternative to aortic valve replacement, which remains the best treatment for calcified aortic stenosis; the benefits and long-term results of aortic valve replacement are well established, even in the elderly.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Charles Nicolle Hospital, Rouen, France.
authors.forename: R
authors.initials: R
authors.lastname: Soyer
authors.forename: F
authors.initials: F
authors.lastname: Bouchart
authors.forename: J P
authors.initials: JP
authors.lastname: Bessou
authors.forename: M
authors.initials: M
authors.lastname: Redonnet
authors.forename: D
authors.initials: D
authors.lastname: Mouton-Schleifer
authors.forename: G
authors.initials: G
authors.lastname: Derumeaux
authors.forename: J
authors.initials: J
authors.lastname: Arrignon
authors.forename: B
authors.initials: B
authors.lastname: Letac
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001021:Aortic Valve / Q000473:pathology; D001024:Aortic Valve Stenosis / Q000628:therapy*; D001705:Bioprosthesis; D002114:Calcinosis / Q000473:pathology / Q000628:therapy; D002404:Catheterization; D005260:Female; D006350:Heart Valve Prosthesis / Q000401:mortality; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D015996:Survival Rate; D013997:Time Factors