title: Long-term effects of antineoplastic chemotherapy and radiotherapy on dental development.
abstract: Advances in treatment protocols over the past 20 years have resulted in much improved survival rates for children with cancer. As more children survive, the emphasis has moved from "saving children at all costs' to saving children "at least cost to the child' and protocols are continually reviewed with this in mind. As more dental practitioners are likely to encounter children who have survived malignant disease, this paper looks at the long-term effects of treatment modalities on the dentoalveolar complex.
authors.affiliation: University of Newcastle upon Tyne.
authors.forename: A
authors.initials: A
authors.lastname: Maguire
authors.forename: R R
authors.initials: RR
authors.lastname: Welbury
mesh_terms: D000293:Adolescent; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002648:Child; D002675:Child, Preschool; D016371:Cranial Irradiation / Q000009:adverse effects*; D006258:Head and Neck Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D006801:Humans; D008445:Maxillofacial Development / Q000187:drug effects / Q000528:radiation effects; D009059:Mouth Diseases / Q000209:etiology; D009805:Odontogenesis / Q000187:drug effects* / Q000528:radiation effects*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000532:radiotherapy; D014071:Tooth Abnormalities / Q000209:etiology
chemical_list: D000970:Antineoplastic Agents