title: Contact allergy in patients with oral symptoms: a study of 47 patients.
abstract: BACKGROUND
  Patients may present with a range of unexplained oral symptoms, and there has been debate about the role of contact sensitivity in these patients.
  
  
  OBJECTIVE
  The aim of this study was to review patch test results in patients presenting with oral and perioral symptoms and to determine the relevance of positive reactions.
  
  
  METHODS
  Forty-seven patients with oral symptoms were studied. Patients were tested to the European Standard Series and a range of other allergens, including bakery products, dental materials, medicaments, and metals.
  
  
  RESULTS
  Sixty-four percent of the patients had one or more positive allergic reactions. In 14 patients (30%), the results were believed to be relevant to their clinical problem. Relevant allergens included metals, rubber chemicals, food additives, and dental products. Symptoms resolved rapidly in all of the 13 patients in whom the source of the offending allergen was removed.
  
  
  CONCLUSIONS
  Patch testing is a useful investigation in patients with unexplained oral and perioral symptoms. Avoidance of the relevant allergen can result in complete resolution of symptoms.
authors.affiliation: University Department of Dermatology, Royal Hallamshire Hospital, Sheffield, England.
authors.forename: M
authors.initials: M
authors.lastname: Shah
authors.forename: F M
authors.initials: FM
authors.lastname: Lewis
authors.forename: D J
authors.initials: DJ
authors.lastname: Gawkrodger
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000485:Allergens; D002648:Child; D003764:Dental Materials / Q000009:adverse effects; D003877:Dermatitis, Contact / Q000150:complications*; D005260:Female; D005503:Food Additives / Q000009:adverse effects; D006801:Humans; D008047:Lip Diseases / Q000209:etiology; D008297:Male; D008670:Metals / Q000009:adverse effects; D008875:Middle Aged; D009059:Mouth Diseases / Q000209:etiology*; D012882:Skin Tests
chemical_list: D000485:Allergens; D003764:Dental Materials; D005503:Food Additives; D008670:Metals