title: [Diagnostic value of various echo- and Doppler echocardiography methods in quantifying mitral valve stenosis].
abstract: Two-dimensional and Doppler echocardiography have been widely used for noninvasive determination of valve area in patients with mitral stenosis. Recent studies have indicated that the Doppler-echocardiographic pressure half-time method (PHT) does not accurately predict mitral orifice area (MOA). Therefore, applications of the continuity equation and the Gorlin formula have been used additionally to the PHT for Doppler-echocardiographic assessment of MOA. In a prospective study of 34 patients MOA determined by two-dimensional and Doppler echocardiography was compared with MOA measured by cardiac catheterization (range 0.40 to 1.90 cm2, mean 1.08 +/- 0.37 cm2). There was a moderate correlation between two-dimensional echocardiographic and invasive measurements (r = 0.65, SEE = 0.20 cm2). MOA calculated by the PHT showed only poor correlation with cardiac catheterization (r = 0.38 SEE = 0.37 cm2). We found better correlations for the continuity equation (r = 0.73, SEE = 0.35 cm2) and Doppler-echocardiographic application of the Gorlin formula (r = 0.81, SEe = 0.27 cm2). Doppler-echocardiographic use of the Gorlin formula yielded the best prediction of the severity of mitral valve stenosis (concordance with invasive measurement in 82%).
  
  
  CONCLUSIONS
  Pressure half-time is only a poor predictor of the severity of mitral valve stenosis. More accurate results are obtained by Doppler-echocardiographic applications of the continuity equation and especially the Gorlin formula.
authors.affiliation: Universitätsklinik Freiburg Innere Medizin III--Abteilung Kardiologie und Angiologie.
authors.forename: M
authors.initials: M
authors.lastname: Handke
authors.forename: A
authors.initials: A
authors.lastname: Geibel
authors.forename: W
authors.initials: W
authors.lastname: Kasper
authors.forename: M
authors.initials: M
authors.lastname: Olschewski
authors.forename: I
authors.initials: I
authors.lastname: Simon
authors.forename: S
authors.initials: S
authors.lastname: Konstantinides
authors.forename: H
authors.initials: H
authors.lastname: Just
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000503:physiopathology; D001783:Blood Flow Velocity / Q000502:physiology; D006328:Cardiac Catheterization; D004452:Echocardiography; D015150:Echocardiography, Doppler; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000503:physiopathology; D008946:Mitral Valve Stenosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D011446:Prospective Studies
vernacular_title: Diagnostischer Stellenwert verschiedener echo- und Doppler-echokardiographischer Methoden in der Quantifizierung von Mitralklappenstenosen.