title: [Miliary dissemination with pulmonary involvement secondary to intravesical immunotherapy with Calmette-Guérin bacillus].
abstract: We describe the case of a 67-years-old man who underwent transurethral resection and immunotherapy with Calmette-Guérin bacillus solution (CGB) for superficial transitional carcinoma of the bladder. After a series of intravesical irrigations with CGB, the patient developed fever, asthenia and persistent anorexia and was hospitalized. After testing he was diagnosed of miliary tuberculosis due to CGB and died in spite of tuberculostatic therapy. Hematogenous dissemination, a rare but serious complication of vesical irrigation with CGB, is thought to be more common than previously suspected. It should be suspected in all patients receiving CGB when a compatible clinical picture presents. An understanding of this complication and early establishment of specific treatment is the only wat to improve prognosis.
authors.affiliation: Sección de Neumología, Hospital del Río Hortega, Valladolid.
authors.forename: C
authors.initials: C
authors.lastname: Paredes Arranz
authors.forename: J F
authors.initials: JF
authors.lastname: de Frutos Arribas
authors.forename: J
authors.initials: J
authors.lastname: Calleja Escudero
authors.forename: M
authors.initials: M
authors.lastname: Blanco Cabero
authors.forename: F
authors.initials: F
authors.lastname: del Campo Matías
authors.forename: M C
authors.initials: MC
authors.lastname: Velasco
mesh_terms: D000283:Administration, Intravesical; D000368:Aged; D001500:BCG Vaccine / Q000009:adverse effects*; D002295:Carcinoma, Transitional Cell / Q000628:therapy; D006801:Humans; D008297:Male; D014391:Tuberculosis, Miliary / Q000209:etiology*; D001749:Urinary Bladder Neoplasms / Q000628:therapy
chemical_list: D001500:BCG Vaccine
vernacular_title: Diseminación miliar con afectación pulmonar secundaria a inmunoterapia intravesical con bacilo de Calmette-Guérin.