title: [Sarcoma botryoides in the pediatric vagina--a soft tissue sarcoma with good prognosis].
abstract: Although rare, sarcoma botryoides of the vagina in infants is a highly aggressive soft tissue tumour. Former opinions suggesting exenterative surgery and radiation to improve the dismal outcome in these young children, are outdated. Due to balanced therapies (topical tumourectomy, chemotherapy and radiation adjusted to tumour stage) cure of these sarcomas may be expected dependent on tumour stage, localisation and response to chemotherapy. The rate of complete remissions has increased in recent years. We report on an eighteen-month old girl with complete remission of tumour stage IIA who had been treated according to the CWS 91 protocol. Diagnosis and treatment were performed in March 1994 at the age of six months. We observed the patient in complete remission for 8 months (till September 1995).
authors.affiliation: Gynäkologische & Geburtshilfliche Abteilung, Krankenanstalt Rudolfstiftung, Wier.
authors.forename: F
authors.initials: F
authors.lastname: Wierrani
authors.forename: A
authors.initials: A
authors.lastname: Zoubek
authors.forename: W
authors.initials: W
authors.lastname: Grin
authors.forename: M
authors.initials: M
authors.lastname: Kronberger
authors.forename: J
authors.initials: J
authors.lastname: Preiser
authors.forename: C
authors.initials: C
authors.lastname: Gabriel
authors.forename: B
authors.initials: B
authors.lastname: Bibus
authors.forename: E
authors.initials: E
authors.lastname: Koscielniak
authors.forename: H
authors.initials: H
authors.lastname: Gadner
authors.forename: W
authors.initials: W
authors.lastname: Grünberger
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D009367:Neoplasm Staging; D018233:Rhabdomyosarcoma, Embryonal / Q000151:congenital* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D014621:Vagina / Q000473:pathology / Q000601:surgery; D014625:Vaginal Neoplasms / Q000151:congenital* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor
vernacular_title: Das Sarcoma Botryoides der kindlichen Vagina--Ein Weichteilsarkom mit guten Heilungschancen.