Proton long-range migration along protein monolayers and its consequences on membrane coupling.
It has been shown with lipid layers and more recently with purple membranes that protons have slow surface-to-bulk transfer. This results in long-range proton lateral conduction along membranes. We report here that such lateral transfer can take place along a pure protein film. It is strongly controlled by the packing. Subtle reorganizations of the protein-protein contact can be biological switches between interfacial and delocalized proton pathways between sources and sinks.
Gabriel
B
B
Institut de Pharmacologie et de Biologie Structurale-Centre National de la Recherche Scientifique, Toulouse, France.
Teissié
J
J
D005453:Fluorescence; D006863:Hydrogen-Ion Concentration; D008051:Lipid Bilayers / Q000737:chemistry; D011522:Protons; D012710:Serum Albumin, Bovine / Q000737:chemistry*
D008051:Lipid Bilayers; D011522:Protons; D012710:Serum Albumin, Bovine