title: Extravasation of thrombus into the aortic root: a complication following use of an infusion catheter for intragraft thrombolysis.
abstract: Overnight chronic urokinase infusion was used to successfully treat thrombotic occlusion of a saphenous vein graft. Following removal of the infusion catheter, a 3-cm linear thrombus was observed extending from the graft into the ascending aorta. This mobile thrombus was successfully treated with coumadinization for 9 wk. Potential preventive measures for this complication of indwelling catheters are discussed.
authors.affiliation: Department of Medicine, Beth Israel Hospital Boston, Massachusetts 02215, USA.
authors.forename: R P
authors.initials: RP
authors.lastname: Caputo
authors.forename: D J
authors.initials: DJ
authors.lastname: Cohen
authors.forename: D S
authors.initials: DS
authors.lastname: Baim
authors.forename: R E
authors.initials: RE
authors.lastname: Kuntz
mesh_terms: D001011:Aorta; D002408:Catheters, Indwelling / Q000009:adverse effects*; D001026:Coronary Artery Bypass; D006083:Graft Occlusion, Vascular / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010960:Plasminogen Activators / Q000008:administration & dosage*; D012501:Saphenous Vein / Q000637:transplantation; D015912:Thrombolytic Therapy / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods; D013927:Thrombosis / Q000150:complications* / Q000188:drug therapy*; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage*
chemical_list: D010960:Plasminogen Activators; D014568:Urokinase-Type Plasminogen Activator