title: [The effect of naloxone on rhythm disorders and on the conduction system of the heart].
abstract: In experimental arrhythmias induced in rabbits by strophanthin, epinephrine, and calcium chloride the high antiarrhythmic efficacy of Naloxone was proved. No antiarrhythmic activity of Naloxone was observed in aconitine models. The intravenous administration of Naloxone to normal adults (0.4 - 0.8 mg) increased the sinus cycle length, sinus node recovery time (SNRT), CSNRT, and sinoatrial conduction time.
authors.forename: E V
authors.initials: EV
authors.lastname: Shliakhto
authors.forename: A A
authors.initials: AA
authors.lastname: Zaĭtsev
authors.forename: A V
authors.initials: AV
authors.lastname: Panov
authors.forename: A V
authors.initials: AV
authors.lastname: Ardashev
authors.forename: E M
authors.initials: EM
authors.lastname: Nifontov
authors.forename: E A
authors.initials: EA
authors.lastname: Kashina
authors.forename: V V
authors.initials: VV
authors.lastname: Kazarin
authors.forename: V V
authors.initials: VV
authors.lastname: Ivanov
mesh_terms: D000328:Adult; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000139:chemically induced / Q000188:drug therapy*; D002304:Cardiac Pacing, Artificial; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D004562:Electrocardiography / Q000187:drug effects; D006329:Heart Conduction System / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008297:Male; D009270:Naloxone / Q000494:pharmacology* / Q000627:therapeutic use*; D011817:Rabbits; D012016:Reference Values
chemical_list: D000889:Anti-Arrhythmia Agents; D009270:Naloxone
vernacular_title: Vliianie naloksona na narusheniia ritma i provodiashchuiu sistemu serdtsa.