[Laser fluorescence spectroscopy in intraoperative diagnosis and staging of lung cancer].
67 patients with different kind of lung diseases have been evaluated by intraoperative laser spectroscopy. 49 of them had lung cancer and 18 patients had nonmalignant tumors, tuberculomas and chronic abscess. Helium-neon laser has been used to study spectral parameters of a normal lung tissue and lungs with malignant and benign tumors intraoperatively. It was found that intensity of autofluorescence will increase in cancer tissue. This phenomenon may be used for differential diagnosis of a lung cancer with benign tumors and chronic pulmonary diseases. It was also shown that autofluorescence of metastatic lymph nodes is higher compared to their hyperplasia. That may be used for rapid diagnosis of metastases in mediastinal lymph nodes and intraoperative staging of lung cancer.
Uspenskiĭ
L V
LV
Kuzin
M I
MI
Ablitsov
I A
IA
Rybin
V K
VK
Loshchenov
V B
VB
D003937:Diagnosis, Differential; D005471:Fluoroscopy; D006801:Humans; D007430:Intraoperative Care; D008171:Lung Diseases / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008175:Lung Neoplasms / Q000473:pathology*; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*
Lazernaia fluorestsentnaia spektroskopiia v intraoperatsionnoĭ diagnostike i otsenke rasprostranennosti raka lëgkogo.