New aspects in scleroderma research.
Systemic sclerosis (SSc) still is a disease of unknown origin. However, in the past few years, progress has been made in elucidating some features of SSc. In this review we summarize recently established data that center around genetics, immunology, and animal models of SSc as well as around the important role of cytokines, endothelial cells, fibroblasts and the extracellular matrix in this disease.
Sollberg
S
S
Department of Dermatology, University of Köln, Germany.
Krieg
T
T
D000818:Animals; D016207:Cytokines / Q000276:immunology; D004195:Disease Models, Animal; D004730:Endothelium, Vascular / Q000276:immunology; D005109:Extracellular Matrix / Q000276:immunology; D005347:Fibroblasts / Q000276:immunology; D006801:Humans; D012595:Scleroderma, Systemic / Q000235:genetics / Q000276:immunology
D016207:Cytokines