title: Halymecins, new antimicroalgal substances produced by fungi isolated from marine algae.
abstract: Novel antimicroalgal substances halymecins A (1), B (2) and C (3) were isolated from the fermentation broth of a Fusarium sp. and halymecins D (4) and E (5) from an Acremonium sp. The structures of these halymecins, Fig. 1, were determined based on extensive 2D NMR studies as well as mass spectral data. These chemical structures are conjugates of di- and trihydroxydecanoic acid. Halymecin A showed antimicroalgal activity against Skeletonema costatum.
authors.affiliation: Marine Biotechnology Institute, Shimizu Laboratories, Shizuoka, Japan.
authors.forename: C
authors.initials: C
authors.lastname: Chen
authors.forename: N
authors.initials: N
authors.lastname: Imamura
authors.forename: M
authors.initials: M
authors.lastname: Nishijima
authors.forename: K
authors.initials: K
authors.lastname: Adachi
authors.forename: M
authors.initials: M
authors.lastname: Sakai
authors.forename: H
authors.initials: H
authors.lastname: Sano
mesh_terms: D000164:Acremonium / Q000145:classification / Q000378:metabolism*; D003652:Decanoic Acids / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology*; D056890:Eukaryota / Q000187:drug effects* / Q000382:microbiology; D005670:Fusarium / Q000145:classification / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D016339:Spectrometry, Mass, Fast Atom Bombardment
chemical_list: D003652:Decanoic Acids