Ovulation induction for infertility is it safe or not?
Case reports of ovarian tumors in women undergoing fertility treatment have raised questions about the potential neoplastic effects of ovulation-induction agents used in the treatment of infertility. This has been the subject of much debate, media coverage and patient alarm. An increased risk of malignant epithelial ovarian cancer, borderline epithelial ovarian tumors, and nonepithelial ovarian cancer have been reported in association with the use of fertility drugs. Further review of the literature reveals that there are limitations to the studies reporting this association and indicates that further research is needed before a causal relationship can be established.
Anderson
S M
SM
USD School of Medicine, Canistota, USA.
Dimitrievich
E
E
D000328:Adult; D000367:Age Factors; D000368:Aged; D016022:Case-Control Studies; D002996:Clomiphene / Q000009:adverse effects; D005260:Female; D005300:Fertility Agents, Female / Q000009:adverse effects*; D006801:Humans; D015994:Incidence; D007247:Infertility, Female / Q000150:complications; D008596:Menotropins / Q000009:adverse effects; D008875:Middle Aged; D010062:Ovulation Induction / Q000009:adverse effects*; D010298:Parity; D011247:Pregnancy; D012106:Research; D012307:Risk Factors; D014594:Uterine Neoplasms / Q000139:chemically induced* / Q000453:epidemiology
D005300:Fertility Agents, Female; D002996:Clomiphene; D008596:Menotropins