title: Evaluation of mixed venous oxygen saturation in chronic severe mitral regurgitation.
abstract: OBJECTIVE
  The objective of this study was to evaluate whether chronic severe mitral regurgitation leads to an artifactual elevation of mixed venous oxygen saturation.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  University hospital setting.
  
  
  METHODS
  Thirty patients with chronic severe mitral regurgitation undergoing surgery on the mitral valve and 25 patients without mitral regurgitation scheduled for elective coronary artery surgery.
  
  
  METHODS
  Blood samples were simultaneously withdrawn from the distal port and the paceport of a pulmonary artery catheter.
  
  
  RESULTS
  During steady-state-anesthesia, oxygen saturation and hemoglobin concentration were measured. There was no difference between mean oxygen saturation in blood from the pulmonary artery and the right ventricle in patients with mitral regurgitation, no matter whether large v waves were present, and in patients without mitral regurgitation. The distribution of individual differences between mixed venous and right ventricular oxygen saturation did not differ between groups.
  
  
  CONCLUSIONS
  Because mixed venous oxygen saturation is not affected by chronic severe mitral regurgitation, it can be used in patients with mitral regurgitation just as in patients without mitral regurgitation.
authors.affiliation: Department of Anesthesiology, University Hospital, Regensburg, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Rödig
authors.forename: G
authors.initials: G
authors.lastname: Wiesner
authors.forename: C
authors.initials: C
authors.lastname: Keyl
authors.forename: J
authors.initials: J
authors.lastname: Hobbhahn
mesh_terms: D000328:Adult; D000368:Aged; D002908:Chronic Disease; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000097:blood*; D010100:Oxygen / Q000097:blood*; D011446:Prospective Studies; D011669:Pulmonary Wedge Pressure; D014680:Veins
chemical_list: D006454:Hemoglobins; D010100:Oxygen