title: [Acute thrombocytopenic purpura following rubella vaccination].
abstract: A case of acute thrombocytopenic purpura following rubella vaccination is reported. A 3-year-old boy developed purpura on the 22nd days after rubella vaccination. His platelet count was 34 x 10(3)/microliter. Platelet-associated IgG was elevated, but the amount of megakaryocytes in bone marrow aspirates was within the normal range, suggesting immune mechanism-associated thrombocytopenia. He recovered spontaneously within one month. Thrombocytopenic purpura is a well-documented complication of natural rubella infection. Attention should be paid rubella vaccination-associated thrombocytopenia, though it seems to be less frequent than after natural infections.
authors.affiliation: Department of Pediatrics, Kinki University School of Medicine.
authors.forename: T
authors.initials: T
authors.lastname: Yamamoto
authors.forename: T
authors.initials: T
authors.lastname: Kino
authors.forename: K
authors.initials: K
authors.lastname: Yagi
authors.forename: H
authors.initials: H
authors.lastname: Miyata
authors.forename: K
authors.initials: K
authors.lastname: Yoshioka
mesh_terms: D000208:Acute Disease; D002675:Child, Preschool; D006801:Humans; D008297:Male; D011696:Purpura, Thrombocytopenic / Q000209:etiology*; D012411:Rubella Vaccine / Q000009:adverse effects*; D014611:Vaccination
chemical_list: D012411:Rubella Vaccine