Cancer and gene therapy.
The authors review the current literature pertaining to gene therapy as related to human cancer, covering gene therapy strategies, techniques of gene transfer, and targeted gene delivery. Gene therapy has various applications. Many technical obstacles in gene delivery need to be overcome. The safe delivery and expression of a gene to its destination are essential for clinical use. A greater understanding of the genetic basis of cancer and tumor immunology is necessary before the goal of cancer gene therapy can be fully realized.
Schmidt-Wolf
G D
GD
Department of Internal Medicine, Virchow Clinic, Humboldt University, Berlin, Germany.
Schmidt-Wolf
I G
IG
D018014:Gene Transfer Techniques; D015316:Genetic Therapy; D006801:Humans; D007167:Immunotherapy; D008722:Methods; D009369:Neoplasms / Q000628:therapy*