title: [Calcium channel blockers in pregnancy].
abstract: Calcium channel blockers are used more and more in pregnancy. No teratogenic effect has been observed in humans despite the lack of adequate studies. The use of calcium channel blockers in premature labor and in arterial hypertension may be recommended. In premature labor, maternal tolerance is better than that of beta adrenergic drugs. In hypertensive disorders of pregnancy, current data indicate that calcium channel blockers may be a good second line medication. Acute lowering of maternal blood pressure (by sublingual or intravenous use) may however induce fetal distress.
authors.affiliation: Service de Gynécologie-Obstétrique, Hôpital Antoine Béclère, Clamart.
authors.forename: C
authors.initials: C
authors.lastname: Tchobroutsky
mesh_terms: D000959:Antihypertensive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D002121:Calcium Channel Blockers / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy; D015149:Tocolytic Agents / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D015149:Tocolytic Agents
vernacular_title: Antagoniste calcique pendant la grossesse.