[Determination of free radical activity in workers at risk for styrene exposure].
The authors examined indicators of the effect of free radicals (MDA, SOD, GSHPx, selenium) in 38 workers exposed to styrene. They revealed a statistically significant (p < 0.01) correlation of SOD activity and the period of exposure to styrene and also a statistically significant correlation (p < 0.05) between urinary selenium excretion and the period of exposure to styrene as well as a statistically significant correlation (p < 0.01) between the MDA serum concentration and urinary selenium excretion. There is no statistically significant difference between the MDA plasma concentration among smokers and non-smokers, the SOD activity is significantly higher in non-smokers (p < 0.05). Based on the revealed findings the authors assume that free radicals may also play a part in the action of styrene on the organism.
Kohout
J
J
Klinika pracovního lékarstvi, FN Plzen.
Holecek
V
V
Machartová
V
V
Racek
J
J
Jerábek
Z
Z
Senft
V
V
D000328:Adult; D005260:Female; D005609:Free Radicals / Q000378:metabolism*; D005979:Glutathione Peroxidase / Q000097:blood; D006801:Humans; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D016273:Occupational Exposure; D012307:Risk Factors; D012643:Selenium / Q000378:metabolism; D020058:Styrene; D013343:Styrenes / Q000009:adverse effects*; D013482:Superoxide Dismutase / Q000097:blood
D005609:Free Radicals; D013343:Styrenes; D020058:Styrene; D008315:Malondialdehyde; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D012643:Selenium
Stanovení úcinku volných radikálů u pracovnků v riziku styrenu.