title: Oxygen species scavenging activity of phenolic extracts from hawthorn fresh plant organs and pharmaceutical preparations.
abstract: Different extracts of fresh vegetative and reproductive organs from Crataegus monogyna harvested during a whole season and from some pharmaceutical hawthorn preparations exhibit in vitro antioxidant activities using three different models of oxygen reactive species generation (superoxide anion, hydrogen peroxide and hypochlorous acid). All the tested samples show low IC50 values, the most efficient being fresh young leaves, fresh floral buds and pharmaceutical dried flowers. The activities seem to be especially bound to the total phenolic proanthocyanidin and flavonoid contents.
authors.affiliation: Laboratoire de Pharmacognosie, Faculté des Sciences Pharmaceutiques et Biologiques, Lille, France.
authors.forename: T
authors.initials: T
authors.lastname: Bahorun
authors.forename: B
authors.initials: B
authors.lastname: Gressier
authors.forename: F
authors.initials: F
authors.lastname: Trotin
authors.forename: C
authors.initials: C
authors.lastname: Brunet
authors.forename: T
authors.initials: T
authors.lastname: Dine
authors.forename: M
authors.initials: M
authors.lastname: Luyckx
authors.forename: J
authors.initials: J
authors.lastname: Vasseur
authors.forename: M
authors.initials: M
authors.lastname: Cazin
authors.forename: J C
authors.initials: JC
authors.lastname: Cazin
authors.forename: M
authors.initials: M
authors.lastname: Pinkas
mesh_terms: D000872:Anthocyanins / Q000737:chemistry; D000975:Antioxidants / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D002855:Chromatography, Thin Layer; D005419:Flavonoids / Q000737:chemistry; D016166:Free Radical Scavengers / Q000737:chemistry* / Q000302:isolation & purification; D006861:Hydrogen Peroxide / Q000737:chemistry; D006997:Hypochlorous Acid / Q000737:chemistry; D010636:Phenols; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D044945:Proanthocyanidins; D017382:Reactive Oxygen Species / Q000378:metabolism*; D013481:Superoxides / Q000737:chemistry
chemical_list: D000872:Anthocyanins; D000975:Antioxidants; D005419:Flavonoids; D016166:Free Radical Scavengers; D010636:Phenols; D010936:Plant Extracts; D044945:Proanthocyanidins; D017382:Reactive Oxygen Species; D013481:Superoxides; C013221:proanthocyanidin; D006997:Hypochlorous Acid; D006861:Hydrogen Peroxide