title: Assessment of lipid peroxidation in rats of different body weight by determining expired ethane.
abstract: Expired ethane is regarded as an indicator of reactive oxygen species induced lipid peroxidation. We investigated whether Wistar rats of different body weights (BW: 78 +/- 6, 121 +/- 12 and 347 +/- 30 g) and hence different metabolic rates per unit weight, expire different amounts of ethane. We found that expired ethane (pmol/100 g BW/min) decreases with increasing BW (8.6 +/- 1.8, 6.3 +/- 1.5 and 2.8 +/- 0.6, respectively). These values aas well as a recently published average value of 1.0 pmol ethane/100 g BW/min for healthy humans (average BW: 78 kg) indicate a positive relationship between lipid peroxidation and metabolic rate.
authors.affiliation: Forschungsinstitut für Kinderernährung, Dortmund, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Topp
authors.forename: M
authors.initials: M
authors.lastname: Vangala
authors.forename: K
authors.initials: K
authors.lastname: Kritzler
authors.forename: G
authors.initials: G
authors.lastname: Schöch
mesh_terms: D000818:Animals; D001835:Body Weight / Q000502:physiology*; D001944:Breath Tests; D004734:Energy Metabolism / Q000502:physiology; D004980:Ethane / Q000032:analysis*; D007700:Kinetics; D015227:Lipid Peroxidation / Q000502:physiology*; D018482:Muscle, Skeletal / Q000033:anatomy & histology / Q000502:physiology; D009929:Organ Size / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D017382:Reactive Oxygen Species
chemical_list: D017382:Reactive Oxygen Species; D004980:Ethane