Impact of myeloablative therapy with bone marrow transplantation in advanced neuroblastoma.
Current results suggest that purged autologous bone marrow transplant may improve outcome for some subsets of high risk neuroblastoma, but the risk of relapse is still high.
Matthay
K K
KK
Pediatric Clinical Oncology, University of California, San Francisco 94143-0106, USA.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000032:analysis; D001855:Bone Marrow Diseases / Q000139:chemically induced / Q000628:therapy; D016465:Bone Marrow Purging; D016026:Bone Marrow Transplantation; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D016259:Genes, myc; D006801:Humans; D007223:Infant; D015993:Life Tables; D018365:Neoplasm, Residual; D009447:Neuroblastoma / Q000188:drug therapy* / Q000401:mortality / Q000628:therapy; D010865:Pilot Projects; D016016:Proportional Hazards Models; D012306:Risk; D019172:Transplantation Conditioning; D014182:Transplantation, Autologous; D016896:Treatment Outcome; D014916:Whole-Body Irradiation
D014408:Biomarkers, Tumor