Crohn's-like colitis in glycogen storage disease Ib: a case report.
Association between glycogen storage disease type Ib and Crohn's like disease is rare. We present one such case. A young woman with glycogen storage disease type Ib underwent a right hemicolectomy for stenosis and a blind fistulous tract. The histological picture of the resected bowel was consistent with the diagnosis of Crohn's like disease. A leak in the entero-colostomy occurred during medical treatment with steroids, sulfasalazine, and methronidazole. Partial ileal and colonic resection and a new anastomosis were then performed. Recombinant human colony-stimulating factor (300 mcg/die subcutaneously) was then started. The neutrophils promptly increased to a normal range, and the neutrophil function tests improved. The postoperative course was uneventful and the patient did not have a relapse of the bowel disease.
Franceschini
R
R
Department of Internal Medicine, University of Genoa, Italy.
Gianetta
E
E
Pastorino
A
A
Dallegri
F
F
Cataldi
A
A
Corsini
G
G
Barreca
T
T
D000328:Adult; D000714:Anastomosis, Surgical; D003082:Colectomy; D003092:Colitis / Q000150:complications* / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D003125:Colostomy; D005260:Female; D005953:Glycogen Storage Disease Type I / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D011183:Postoperative Complications