Histological correlates of metastasis in primary invasive squamous cell carcinoma of the lip.
The histological features of 66 cases of squamous cell carcinoma of the lip were studied in an attempt to define prognostic parameters. Features that correlated with an increased risk of metastasis included histological grade of the tumour at the base and the surface, the tumour thickness, presence of stromal sclerosis, and the presence of muscle and perineural invasion.
Saywell
M S
MS
Department of Dermatology, Royal Brisbane Hospital, Herston, Queensland, Australia.
Weedon
D
D
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001315:Australia; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008048:Lip Neoplasms / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000473:pathology; D011379:Prognosis; D016016:Proportional Hazards Models; D012044:Regression Analysis; D012307:Risk Factors; D012680:Sensitivity and Specificity; D015996:Survival Rate