[The nootropic correction of disorders in learning and memory processes induced by extreme exposures].
Experiments on rats demonstrated that the low-intensity electromagnetic field (12.6 cm, 2375 MHz, power density 1 mW/cm2), motion sickness, and electroconvulsive shock provoked the retrograde amnesia in the passive avoidance test. The oxyracetam (100 mg/kg, i.p.), aniracetam (50 mg/kg, i.p.), nooglutil (50 mg/kg, i.p.), meclofenoxate (50 mg/kg, i.p.), pyracetam (200 mg/kg, i.p.), and GABA (200 mg/kg, i.p) prevented the memory-impairing effect of all these extreme factors. On the contrary, the N-acetylglycinamide, semax, and other nootropic drugs were effective only under one or two extreme conditions.
Iasnetsov
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VV
Krylova
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IN
Popov
V M
VM
D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects; D003214:Conditioning, Classical / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D004574:Electromagnetic Fields / Q000009:adverse effects; D004597:Electroshock / Q000009:adverse effects; D007859:Learning Disabilities / Q000188:drug therapy* / Q000209:etiology; D008297:Male; D008569:Memory Disorders / Q000188:drug therapy* / Q000209:etiology; D009041:Motion Sickness / Q000150:complications / Q000188:drug therapy; D018697:Nootropic Agents / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors
D018697:Nootropic Agents
Korrektsiia nootropami narusheniĭ protsessov obucheniia i pamiati, vyzvannykh nekotorymi ékstremal'nymi vozdeĭstviiami.