title: Abnormal head MRI in a neurologically normal boy with hypomelanosis of Ito.
abstract: We report on an 8.5-year-old boy with hypomelanosis of Ito (HI) who has an abnormal MRI of the brain but is neurologically normal. There have been many reports of abnormal brain imaging studies in patients with HI, but all reported patients have had abnormal neurologic findings or symptoms. Our patient has had serial, stable head MRI white matter changes and has remained neurologically normal without any neurologic sequelae.
authors.affiliation: Department of Pediatrics, University of Virginia Health Sciences Center, Charlottesville 22908, USA.
authors.forename: J S
authors.initials: JS
authors.lastname: Fryburg
authors.forename: K Y
authors.initials: KY
authors.lastname: Lin
authors.forename: J
authors.initials: J
authors.lastname: Matsumoto
mesh_terms: D001921:Brain / Q000473:pathology*; D002648:Child; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009460:Neurologic Examination; D010859:Pigmentation Disorders / Q000150:complications / Q000235:genetics* / Q000473:pathology* / Q000503:physiopathology; D017689:Polydactyly / Q000150:complications; D013576:Syndactyly / Q000150:complications