title: The effects of fronto-parieto-squamosal suture fusion on cranial growth: an experimental study.
abstract: Craniosynostoses have been known for at least 20 centuries, but their etiopathogeneses are still unclear. There are three main theories to explain the etiology of craniosynostosis, Moss's theory being the most popular. According to Moss, the development of the neurocranial form is viewed as an integration of the growth of the skull base, the calvarial bones, the meninges, and the enclosed brain. Experimental studies, however, are generally focused on cranial vault suture synostosis. This study aims to demonstrate the effects of cranial base synostosis by performing fronto-parieto-squamosal suture fusion. This fusion affected the whole cranial configuration. These effects were more prominent closer to the cranial vault, increasing at the anterior facial height and the lower facial length, reflected by ventral dislocation of the total face, and increasing of the kyphosis at the cranial base. It has also been demonstrated that synostosis of a junction point near the cranial base affects the vault and the base simultaneously. Any approach that tries to treat the cause, and not the symptom, of synostosis must, then, be based on an understanding of how cranial growth occurs and of how sutural growth processes are related to the totality of cranial growth.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Ege University Medical School, Izmir, Turkey.
authors.forename: O
authors.initials: O
authors.lastname: Ulgen
authors.forename: R
authors.initials: R
authors.lastname: Gençosmanoğlu
authors.forename: R
authors.initials: R
authors.lastname: Cankayali
authors.forename: G
authors.initials: G
authors.lastname: Taşdemir
authors.forename: S
authors.initials: S
authors.lastname: Mutluer
authors.forename: E
authors.initials: E
authors.lastname: Songür
mesh_terms: D000818:Animals; D001921:Brain / Q000254:growth & development; D002508:Cephalometry; D003393:Cranial Sutures / Q000503:physiopathology; D003398:Craniosynostoses / Q000209:etiology* / Q000503:physiopathology; D005624:Frontal Bone / Q000601:surgery; D008445:Maxillofacial Development; D010294:Parietal Bone / Q000601:surgery; D011817:Rabbits; D012886:Skull / Q000254:growth & development*; D019291:Skull Base / Q000503:physiopathology*; D016896:Treatment Outcome