title: Chemical and physical stability of perfluorocarbons with laser treatment.
abstract: Physical and toxicological aspects of different perfluorocarbons and semifluorinated compounds are discussed. The urgent need for ultrapurification of perfluorocarbons is demonstrated. In vitro laser treatment simulating physiological conditions of two ultrapurified perfluorocarbons used for temporary tamponade and mechanical fixation of unfolded retina in case of giant tears, and one semifluorinated diether resulted in no detectable chemical alteration. Cytotoxic examinations of both laser treated and untreated probes showed no difference in cell proliferation.
authors.affiliation: Department of Chemistry of Biocompatible Compounds, University of Ulm, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Meinert
authors.forename: J
authors.initials: J
authors.lastname: Mader
authors.forename: W
authors.initials: W
authors.lastname: Röhlke
authors.forename: U
authors.initials: U
authors.lastname: Geister
authors.forename: G E
authors.initials: GE
authors.lastname: Lang
authors.forename: G K
authors.initials: GK
authors.lastname: Lang
authors.forename: C F
authors.initials: CF
authors.lastname: Kreiner
mesh_terms: D002455:Cell Division / Q000528:radiation effects; D002460:Cell Line; D004355:Drug Stability; D005459:Fluorides / Q000378:metabolism; D005466:Fluorocarbons / Q000737:chemistry* / Q000528:radiation effects*; D007477:Ions; D007834:Lasers
chemical_list: D005466:Fluorocarbons; D007477:Ions; D005459:Fluorides