[Anemia due to chronic lead poisoning].
We report a case of anemia due to chronic lead poisoning. A 46-year-old female was admitted to our hospital because of general fatigue and anemia. A peripheral blood smear showed basophilic stippling. There was basophilic stippling and nuclear dysplasia of erythroblasts in the bone marrow. Laboratory findings were as follows: RBC 296 X 10(4)/microliter, Hb 8.5 g/dl, blood lead concentration 67 micrograms/dl, urinary lead concentration 309 micrograms/l, blood delta-ALA dehydrase 0.03 mumol/ml, urinary delta-ALA 25.2 mg/l, urinary coproporphyrin 8,810 micrograms/g.Cr, and blood protoporphyrin 612 micrograms/dl. Chronic lead poisoning was diagnosed and she was treated with Ca-EDTA.
Tanaka
K
K
First Department of Internal Medicine, Kurume University School of Medicine.
Sakamoto
A
A
Shiraishi
K
K
Tanaka
M
M
Fukahori
S
S
Mizunoe
K
K
Masuchi
K
K
Jojima
H
H
Osabe
S
S
Imamura
Y
Y
Honda
J
J
Egami
K
K
Natori
H
H
Oizumi
K
K
D000740:Anemia / Q000209:etiology*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007855:Lead Poisoning / Q000150:complications* / Q000175:diagnosis; D008875:Middle Aged