title: Time to initiation of anti-tuberculosis treatment.
abstract: METHODS
  Fairfield Hospital, Victoria, Australia.
  
  
  OBJECTIVE
  To examine delay in initiation of treatment for tuberculosis (TB).
  
  
  METHODS
  Delay in the initiation of treatment for 142 notified TB patients was examined by a retrospective record review. Particular attention was given to the periods between (1) onset of symptoms and initiation of treatment, and (2) determination of sputum positivity and initiation of treatment. An expert panel nominated 30 days and 3 days as 'acceptable' periods for (1) and (2), respectively.
  
  
  RESULTS
  Only 31% of patients commenced treatment within 30 days of onset of symptoms. This was so for both sputum smear-positive and negative cases, and was not significantly related to the site of infection, referral source, age, gender or ethnicity of the patient. Of patients with smear-positive pulmonary TB, 86% received treatment within 3 days of this result being demonstrated. Those with a delay of greater than 3 days were all investigated by private doctors through private laboratories.
  
  
  CONCLUSIONS
  There are appreciable delays in initiation of treatment for TB. Measures to combat these unacceptable delays are discussed.
authors.affiliation: National Centre for Epidemiology and Population Health, Australian National University, Victoria, Australia.
authors.forename: J E
authors.initials: JE
authors.lastname: Pirkis
authors.forename: B R
authors.initials: BR
authors.lastname: Speed
authors.forename: A P
authors.initials: AP
authors.lastname: Yung
authors.forename: D R
authors.initials: DR
authors.lastname: Dunt
authors.forename: C R
authors.initials: CR
authors.lastname: MacIntyre
authors.forename: A J
authors.initials: AJ
authors.lastname: Plant
mesh_terms: D000368:Aged; D000995:Antitubercular Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D012189:Retrospective Studies; D013183:Sputum / Q000382:microbiology; D013997:Time Factors; D014376:Tuberculosis / Q000188:drug therapy*; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy
chemical_list: D000995:Antitubercular Agents