[The evaluation of the effect of zinc sulfate on primary immune response indices under alcoholic intoxication].
Introduction of zinc sulfate in the composition of drinking liquid on the background of alcohol intoxication of animals increases the intensity of primary immune response to the sheep erythrocytes (ShE). This effect is manifested through an increase in the number of phagocytosing lymphocytes in peripheral blood, antibody forming cells in the spleen, antibody titer to ShE, and in an increase in the rosette-forming ability of lymphocytes. The data obtained indicate to the potential use of the zinc salts for immunity correction in conditions of chronic alcohol intoxication.
Proskuriakova
T V
TV
Gurtovenko
V M
VM
Gorshkova
E P
EP
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000437:Alcoholism / Q000188:drug therapy* / Q000276:immunology*; D000818:Animals; D004353:Drug Evaluation, Preclinical; D007111:Immunity, Cellular / Q000187:drug effects; D007114:Immunization / Q000379:methods; D051379:Mice; D008810:Mice, Inbred C57BL; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D019287:Zinc Sulfate / Q000627:therapeutic use*
D000276:Adjuvants, Immunologic; D019287:Zinc Sulfate
Otsenka vliianiia sul'fata tsinka na pokazateli pervichnogo immunnogo otveta v usloviiakh alkogol'noĭ intoksikatsii.