Both IL-2 and IL-4 synergize with IL-12 to induce a CTL response, a response completely blocked by TGF-beta.
Herrmann
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Department of Cellular Immunology Genetics Institute, Inc., Cambridge, Massachusetts 02140, USA. @Genetics.com
Abdi
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K
D000818:Animals; D002478:Cells, Cultured; D016207:Cytokines / Q000502:physiology*; D003602:Cytotoxicity, Immunologic / Q000187:drug effects*; D004357:Drug Synergism; D007371:Interferon-gamma / Q000502:physiology; D018664:Interleukin-12 / Q000008:administration & dosage*; D007376:Interleukin-2 / Q000008:administration & dosage*; D015847:Interleukin-4 / Q000008:administration & dosage*; D015850:Interleukin-6 / Q000502:physiology; D051379:Mice; D008809:Mice, Inbred C3H; D008810:Mice, Inbred C57BL; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology*; D018418:Th2 Cells / Q000276:immunology; D016212:Transforming Growth Factor beta / Q000502:physiology*
D016207:Cytokines; D007376:Interleukin-2; D015850:Interleukin-6; D016212:Transforming Growth Factor beta; D018664:Interleukin-12; D015847:Interleukin-4; D007371:Interferon-gamma