Condylar adaptation after alteration of vertical dimension in adult rhesus monkeys, Macaca mulatta.
Remodeling in the cartilage of the mandibular condyle was investigated in young adult monkeys after an increase in vertical dimension of the midface through the use of a tooth-borne intraoral appliance. Six young adult male rhesus monkeys had bite-splints of 5 mm, 10 mm or 15 mm cemented to their maxillary dentition for 48 weeks. Five age- and sex-matched monkeys were used as controls. The thickness of the articular tissue and of the prechondroblastic and chondroblastic layers of the condylar cartilage in the superior, posterosuperior and posterior regions was measured from parasagittal sections of the temporomandibular joint (TMJ). It was found that articular tissue thickness was reduced in the superior region; the prechondroblastic layer, absent in control animals, was very distinctive (30-75 microns) in experimental animals; and there was a 62% increase in the thickness of the chondroblastic layer in the experimental animals. These findings indicate that chronic alteration of mandibular posture via increase in vertical dimension stimulates progressive remodeling of the mandibular condyle in young adult monkeys.
Sim
Y
Y
Graduate Orthodontic Program, Indiana University School of Dentistry, USA.
Carlson
D S
DS
McNamara
J A
JA
D000222:Adaptation, Physiological; D000704:Analysis of Variance; D000818:Animals; D016723:Bone Remodeling; D002358:Cartilage, Articular / Q000166:cytology / Q000254:growth & development*; D008253:Macaca mulatta; D008297:Male; D008334:Mandible / Q000502:physiology; D008335:Mandibular Condyle / Q000033:anatomy & histology / Q000254:growth & development*; D017090:Occlusal Splints; D013704:Temporomandibular Joint / Q000033:anatomy & histology / Q000254:growth & development*; D014716:Vertical Dimension