Multiple endocrine neoplasia type 1 associated with malignant lymphoma and other complications.
A 49-year-old female with multiple endocrine neoplasia (MEN) type 1 associated with malignant lymphoma, lipoma, functioning adenomatous goiter, non-functioning adrenal tumor, polyneuropathy, postoperative primary hyperparathyroidism, and hepatitis B virus was a human T lymphotropic virus type 1 (HTLV-1) carrier. She underwent parathyroidectomy for primary hyperparathyroidism at age 44. At age 49, examinations of the enlarged para-aortic lymph nodes revealed diffuse small non-cleaved B cell lymphoma in stage II, and other various complications were also found. Multiple tumorigenetic factors were considered to be involved in the present case.
Toshimori
H
H
Third Department of Internal Medicine, Miyazaki Medical College.
Okamoto
M
M
Nakatsuru
K
K
Hidaka
H
H
Yamaguchi
H
H
Ushiroda
Y
Y
Kisanuki
A
A
Tsubouchi
H
H
Sumiyoshi
A
A
Matsukura
S
S
D000310:Adrenal Gland Neoplasms / Q000150:complications; D005260:Female; D006042:Goiter / Q000150:complications; D015490:HTLV-I Infections / Q000150:complications; D006509:Hepatitis B / Q000150:complications; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications; D008067:Lipoma / Q000150:complications; D016393:Lymphoma, B-Cell / Q000150:complications; D008228:Lymphoma, Non-Hodgkin / Q000150:complications; D008875:Middle Aged; D018761:Multiple Endocrine Neoplasia Type 1 / Q000150:complications* / Q000235:genetics