[Pneumoblastoma in children. A clinical case and review of the literature].
Pulmonary blastoma is a rare malignant tumor. A new case is reported in a 3 years 6 month-old girl. An apparent clinical remission was first obtained after a surgical treatment followed by a conventional chemotherapy during six months. Afterwards the persistence of a microscopic residual pulmonary disease lead us to deliver successfully an intensive chemotherapy followed by autologous peripheral blood stem cells reinjection. The child remains disease free 12 months after graft. Problems set by the histogenesis of this tumor, its unspecific clinical and paraclinical features and the role of conventional and intensive chemotherapy followed by autologous bone marrow transplantation are discussed on the basis of a review of 50 cases in the literature.
Bongo
S
S
Fédération d'oncologie pédiatrique du CHR de Marseille, hôpital de La Timone, Marseille, France.
Coze
C
C
Scheiner
C
C
Coquet
M
M
Devred
P
P
Bernard
J L
JL
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D011013:Pneumonectomy; D011379:Prognosis; D018202:Pulmonary Blastoma / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D012086:Reoperation; D016896:Treatment Outcome
Pneumoblastome chez l'enfant. Cas clinique et revue de la littérature.