Sweat testing for the diagnosis of cystic fibrosis: practical considerations.
Most pediatricians eventually encounter a patient with a clinical presentation that warrants the consideration of a sweat test to rule out of confirm the diagnosis of cystic fibrosis. This article discusses, in a series of questions and answers, the currently available sweat testing methods and describes the various methods' reliability, limitations, and frequency of use. In addition, sweat testing utilization and the interpretation and evaluation of test results are discussed so that the clinician can critically analyze the laboratory data.
LeGrys
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Division of Clinical Laboratory Science, University of North Carolina, Chapel Hill School of Medicine 27599-7145, USA.
D001132:Arm; D002712:Chlorides / Q000032:analysis; D003550:Cystic Fibrosis / Q000175:diagnosis*; D004553:Electric Conductivity; D005188:False Negative Reactions; D005189:False Positive Reactions; D006801:Humans; D007231:Infant, Newborn; D007866:Leg; D008722:Methods; D011786:Quality Control; D015203:Reproducibility of Results; D012964:Sodium / Q000032:analysis; D013542:Sweat / Q000737:chemistry* / Q000502:physiology
D002712:Chlorides; D012964:Sodium