Incidence of high-level gentamicin resistance in enterococci at Johannesburg Hospital.
OBJECTIVE
To document the incidence of high-level gentamicin resistance (HLGR) in enterococcal isolates at Johannesburg Hospital.


METHODS
Survey of laboratory isolates.


METHODS
Academic hospitals. BACTERIAL STRAINS: Consecutive samples of enterococcal isolates.


METHODS
The incidence of HLGR in enterococcal isolates.


RESULTS
The incidence of HLGR was 26.5% of Enterococcus faecalis isolates and 20% of E. faecium isolates grown during the study period.


CONCLUSIONS
High-level gentamicin resistance is common among enterococci isolated at Johannesburg Hospital, and this observation must be considered in defining strategies for the management of invasive enterococcal infections in the future.
Keddy
K H
KH
Department of Medical Microbiology, South African Institute for Medical Research, Johannesburg.
Klugman
K P
KP
Liebowitz
L D
LD
D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D004352:Drug Resistance, Microbial; D013293:Enterococcus faecalis / Q000187:drug effects / Q000302:isolation & purification; D016984:Enterococcus faecium / Q000187:drug effects / Q000302:isolation & purification; D005839:Gentamicins / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D006784:Hospitals, Teaching; D006801:Humans; D015994:Incidence; D013019:South Africa / Q000453:epidemiology
D000900:Anti-Bacterial Agents; D005839:Gentamicins