title: Incidence of high-level gentamicin resistance in enterococci at Johannesburg Hospital.
abstract: OBJECTIVE
  To document the incidence of high-level gentamicin resistance (HLGR) in enterococcal isolates at Johannesburg Hospital.
  
  
  METHODS
  Survey of laboratory isolates.
  
  
  METHODS
  Academic hospitals. BACTERIAL STRAINS: Consecutive samples of enterococcal isolates.
  
  
  METHODS
  The incidence of HLGR in enterococcal isolates.
  
  
  RESULTS
  The incidence of HLGR was 26.5% of Enterococcus faecalis isolates and 20% of E. faecium isolates grown during the study period.
  
  
  CONCLUSIONS
  High-level gentamicin resistance is common among enterococci isolated at Johannesburg Hospital, and this observation must be considered in defining strategies for the management of invasive enterococcal infections in the future.
authors.affiliation: Department of Medical Microbiology, South African Institute for Medical Research, Johannesburg.
authors.forename: K H
authors.initials: KH
authors.lastname: Keddy
authors.forename: K P
authors.initials: KP
authors.lastname: Klugman
authors.forename: L D
authors.initials: LD
authors.lastname: Liebowitz
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D004352:Drug Resistance, Microbial; D013293:Enterococcus faecalis / Q000187:drug effects / Q000302:isolation & purification; D016984:Enterococcus faecium / Q000187:drug effects / Q000302:isolation & purification; D005839:Gentamicins / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D006784:Hospitals, Teaching; D006801:Humans; D015994:Incidence; D013019:South Africa / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins