title: Hepatic haemangioendothelioma presenting with early heart failure in a newborn: treatment with hepatic artery embolization and interferon.
abstract: We report our management of a newborn presenting in utero with congestive heart failure secondary to a giant hepatic haemangioendothelioma. Control of heart failure was achieved by transcatheter hepatic artery embolization, and rapid regression of the tumor was observed after a course of alpha 1 interferon. The combination of hepatic artery embolization and interferon may be a useful approach in the management of this rare, potentially fatal condition.
authors.affiliation: Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong.
authors.forename: T F
authors.initials: TF
authors.lastname: Fok
authors.forename: M S
authors.initials: MS
authors.lastname: Chan
authors.forename: C
authors.initials: C
authors.lastname: Metreweli
authors.forename: P C
authors.initials: PC
authors.lastname: Ng
authors.forename: C K
authors.initials: CK
authors.lastname: Yeung
authors.forename: A K
authors.initials: AK
authors.lastname: Li
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D004621:Embolization, Therapeutic; D006333:Heart Failure / Q000209:etiology / Q000628:therapy*; D006390:Hemangioendothelioma / Q000150:complications / Q000628:therapy*; D006499:Hepatic Artery; D006801:Humans; D007231:Infant, Newborn; D016898:Interferon-alpha / Q000627:therapeutic use*; D008113:Liver Neoplasms / Q000150:complications / Q000628:therapy*; D008297:Male
chemical_list: D000970:Antineoplastic Agents; D016898:Interferon-alpha