title: [The epidural administration of steroids and local anesthetics as the basis for the pathogenetic therapy of a radicular pain syndrome in the stages of its development].
abstract: The efficacy of epidural administration of a steroid drug kenalog combined with low-dose 1% lidocaine solution was assessed in 26 patients with discal hernias at various stages of the radicular pain syndrome. Registration of paired H-reflex helped define the neurophysiological criteria objectively indicating cure and normalization of the reduced activities of inhibitory structures of the spinal segmentary system as a result of therapy in patients with the radicular syndrome. The efficacy of this method ranges between 57.3 and 100% and depends on the disease duration, therefore it is preferable at the early stages of the disease (up to 4-6 months). Failure of therapy after 3 successive epidural blockings at 6-7-day intervals may be considered as an indication to surgery.
authors.forename: A V
authors.initials: AV
authors.lastname: Gnezdilov
authors.forename: A V
authors.initials: AV
authors.lastname: Syrovegin
authors.forename: A M
authors.initials: AM
authors.lastname: Ovechkin
authors.forename: A M
authors.initials: AM
authors.lastname: Ivanov
mesh_terms: D000328:Adult; D000779:Anesthetics, Local / Q000008:administration & dosage*; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D005260:Female; D006181:H-Reflex / Q000187:drug effects; D006801:Humans; D007268:Injections, Epidural; D007405:Intervertebral Disc Displacement / Q000150:complications; D008012:Lidocaine / Q000008:administration & dosage*; D017116:Low Back Pain / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011843:Radiculopathy / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D013126:Spinal Nerve Roots; D013577:Syndrome; D013997:Time Factors; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*
chemical_list: D000779:Anesthetics, Local; D000893:Anti-Inflammatory Agents; D008012:Lidocaine; D014222:Triamcinolone Acetonide
vernacular_title: Epidural'noe vvedenie steroidov i mestnykh anestetikov kak osnova patogeneticheskoĭ terapii koreshkovogo bolevogo sindroma na étapakh ego formirovaniia.