Angiographically assessed coronary collateral circulation increases vulnerability to myocardial ischemia during vasodilator stress testing.
In patients with a major coronary vessel occluded, the presence of good coronary collateral circulation increases vulnerability to myocardial ischemia induced by pharmacologic coronary vasodilation. The presence of good collaterals results in a greater frequency, severity, and extent of dipyridamole-induced regional left ventricular dysfunction, consistent with the hypothesis of angiographically assessed collaterals facilitating "steal phenomena" during dipyridamole-induced coronary vasodilation.
Gliozheni
E
E
Institute of Clinical Physiology, C.N.R., Pisa, Italy.
Picano
E
E
Bernardino
L
L
Pingitore
A
A
Sicari
R
R
Marzilli
M
M
D000368:Aged; D003097:Collateral Circulation; D003251:Constriction, Pathologic; D017023:Coronary Angiography; D003326:Coronary Circulation; D003327:Coronary Disease / Q000000981:diagnostic imaging / Q000503:physiopathology*; D004176:Dipyridamole; D004452:Echocardiography; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014665:Vasodilator Agents
D014665:Vasodilator Agents; D004176:Dipyridamole