title: [Primary immunodeficiencies. II. Current therapeutic possibilities].
abstract: The possibilities of the influence of the immune system in patients with primary immunodeficiencies are nowadays limited. Bone marrow transplantation is the only causal treatment at present, but it is used only in patients with the most severe diseases. Gene transplantation is a possible approach in diseases with known genetic defects, but the experience is still very limited. As a replacement therapy, immunoglobulin is the most frequently used, while enzyme replacement therapy has only a restricted applicability. Adequate antibiotic therapy is an essential part of the treatment of the patients with primary immunodeficiencies, both as an adequate and rasant antibiotic treatment of acute infections and also as a long-term antibacterial, and in some cases also anti-viral and anti-fungal prophylaxis.
authors.affiliation: Ustav klinické imunologie LF MU, FN u sv. Anny, Brno.
authors.forename: J
authors.initials: J
authors.lastname: Litzman
mesh_terms: D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000628:therapy*
vernacular_title: Primární imunodeficity. II. Soucasné moznosti terapie.