Pneumocystis carinii from pigs and humans are antigenically distinct.
The antigens of Pneumocystis carinii cysts isolated from pigs and humans were compared by the Western immunoblotting technique. Convalescent pig serum reacted with two antigens (approximately 78 kDa and 32.5 kDa) of porcine P. carinii cysts, whereas convalescent serum from humans did not react with porcine P. carinii cyst antigens. The results indicate that porcine and human P. carinii cysts are antigenically distinct.
Christensen
C B
CB
Centre for Medical Parasitology, University of Copenhagen, Panum Institute. cbvc@biobase.dk
Settnes
O P
OP
Bille-Hansen
V
V
Jorsal
S E
SE
Henriksen
S A
SA
Lundgren
B
B
D000818:Animals; D000908:Antibodies, Fungal / Q000097:blood; D000946:Antigens, Fungal / Q000032:analysis*; D015153:Blotting, Western; D006801:Humans; D011010:Pneumocystis / Q000145:classification* / Q000276:immunology / Q000302:isolation & purification; D011020:Pneumonia, Pneumocystis / Q000276:immunology / Q000382:microbiology* / Q000662:veterinary; D013552:Swine; D013553:Swine Diseases
D000908:Antibodies, Fungal; D000946:Antigens, Fungal