[Immunoglobulin skin and renal deposits in patients with IgA nephropathy and Schonlein-Henoch purpura].
Skin biopsy was performed in 17 of 27 children with IgA nephropathy (IgAN) and 45 of 62 children with Schönlein-Henoch purpura (SHP). Renal biopsy was done in all patients with IgAN and in 51 of 62 with SHP. There was no correlation between presentation of immunological deposits in skin and renal biopsy. Deposits of IgA with or without other deposits or other deposits without IgA were observed in different pathomorphological states. Correlation between IgA serum concentration and presentation of deposits in skin was not observed. Attention was drawn to the high proportion of negative results in skin biopsy.
Szymanik-Grzelak
H
H
Katedra i Klinika Pediatrii i Nefrologii Akademii Medycznej w Warszawie.
Gura
C
C
Kozak-Białasik
D
D
Sulej
J
J
Jarzabek-Chorzelska
M
M
Chadzyńska
M
M
Sieniawska
M
M
D000293:Adolescent; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D005260:Female; D005922:Glomerulonephritis, IGA / Q000276:immunology*; D006417:Hematuria / Q000652:urine; D006801:Humans; D011695:IgA Vasculitis / Q000276:immunology*; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007136:Immunoglobulins / Q000032:analysis*; D007150:Immunohistochemistry; D007223:Infant; D007427:Intracranial Pressure; D008297:Male; D012867:Skin / Q000737:chemistry*
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007136:Immunoglobulins
Złogi immunoglobulin w skórze i nerkach dzieci chorych na nefropatie IgA i zespół Schönleina-Henocha.