title: [Fulminant encephalopathy due to Shigella flexneri].
abstract: BACKGROUND
  In some rare cases, Shigella flexneri infection may be associated with fulminating encephatopathy.
  
  
  METHODS
  A 6-year-old girl was admitted with fever, diarrhea and consciousness abnormalities. Brain CT scan was normal. Shigella flexneri type 2 was isolated from the stools. Despite antibiotic therapy, the encephalopathy was lethal. Two siblings were also infected, the first with only diarrhea, the second with headache and mild consciousness abnormalities: both children had a favorable course.
  
  
  CONCLUSIONS
  Shigella flexneri encephalopathy is associated with high mortality rate in developed countries. Presence of headache could be a poor prognostic factor.
authors.affiliation: Service de pédiatrie, hôpital Jean-Verdier, Bondy, France.
authors.forename: S
authors.initials: S
authors.lastname: Dieu-Osika
authors.forename: M F
authors.initials: MF
authors.lastname: Tazarourte-Pinturier
authors.forename: P
authors.initials: P
authors.lastname: Dessemme
authors.forename: R
authors.initials: R
authors.lastname: Rousseau
authors.forename: S
authors.initials: S
authors.lastname: Sauvion
authors.forename: M
authors.initials: M
authors.lastname: Nathanson
authors.forename: J
authors.initials: J
authors.lastname: Gaudelus
mesh_terms: D002648:Child; D003967:Diarrhea / Q000209:etiology; D004405:Dysentery, Bacillary / Q000175:diagnosis* / Q000628:therapy; D018792:Encephalitis, Viral / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D006801:Humans; D012763:Shigella flexneri
vernacular_title: Encéphalopathie fulminante à Shigella flexneri.