title: Malononitrilamides inhibit the development of various murine graft-vs-host diseases.
authors.affiliation: Research Laboratory, Hoechst Marion Roussell HMR, Marburg, Germany.
authors.forename: H U
authors.initials: HU
authors.lastname: Schorlemmer
authors.forename: R
authors.initials: R
authors.lastname: Kurrle
authors.forename: R R
authors.initials: RR
authors.lastname: Bartlett
mesh_terms: D000480:Alkynes; D000818:Animals; D006086:Graft vs Host Disease / Q000517:prevention & control*; D006087:Graft vs Host Reaction / Q000187:drug effects / Q000276:immunology; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007555:Isoxazoles; D008180:Lupus Erythematosus, Systemic / Q000517:prevention & control*; D017710:Lymphocyte Transfusion; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D008815:Mice, Inbred Strains; D009570:Nitriles / Q000627:therapeutic use*; D051381:Rats; D011917:Rats, Inbred Lew; D011919:Rats, Inbred Strains; D013154:Spleen; D013163:Splenomegaly / Q000517:prevention & control; D013997:Time Factors; D014184:Transplantation, Homologous
chemical_list: D000480:Alkynes; D007166:Immunosuppressive Agents; D007555:Isoxazoles; D009570:Nitriles; C102911:X 910279; C115284:2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide