title: Physical and clinical evaluation of high-resolution thyroid pinhole tomography.
abstract: High-resolution pinhole-SPECT (PSPECT) is a new method for examining the thyroid gland.
  
  
  METHODS
  The camera is tilted slightly so that it is as close to the thyroid as possible. Patients are injected with 185-260 MBq (5-7 mCi) of [99mTc]pertechnetate and examined for 20 min. The reconstruction algorithm is based on filtered back-projection.
  
  
  RESULTS
  We performed static scintigraphy on the thyroids of 114 patients, followed by PSPECT. The major advantage of P SPECT is high resolution. Three- and 4-mm-pinholes produce resolutions of 6 mm and 7 mm, respectively, while resolutions obtained with a parallel collimator are always above 15 mm. The second advantage associated with this method is the good visualization of the cold nodules surrounded by higher activity. Finally, the reconstruction program provides exact sizes of thyroids.
  
  
  CONCLUSIONS
  SPECT is a powerful tool for examining the thyroid.
authors.affiliation: De Bijloke Hospital, Ghent, Belgium.
authors.forename: P M
authors.initials: PM
authors.lastname: Wanet
authors.forename: A
authors.initials: A
authors.lastname: Sand
authors.forename: J
authors.initials: J
authors.lastname: Abramovici
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019047:Phantoms, Imaging; D013670:Sodium Pertechnetate Tc 99m; D013961:Thyroid Gland / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
chemical_list: D013670:Sodium Pertechnetate Tc 99m