title: Endoscopic sinus surgery in the treatment of cystic fibrosis with nasal polyposis.
abstract: We have performed endoscopic sinus surgery on 46 patients with chronic, polypoid rhinosinusitis since 1989. Follow-up ranged from 1 month to 6 years (mean, 28.2 months). Overall, our patients had a 50% chance either of their symptoms returning to preoperative severity or of undergoing a second endoscopic sinus procedure, by 18 to 24 months of postoperative follow-up. Patients with predominantly infective symptoms of mucopurulent rhinorrhea and pain had a significantly better outcome than those with predominantly nasal blockage. The chance of the former group of patients suffering symptom deterioration back to the preoperative state or undergoing a second endoscopic sinus operation was 37% of that of the latter group. The extent of disease on computed tomography scan had no relation to outcome.
authors.affiliation: Department of Otorhinolaryngology, Charing Cross Hospital, London, UK.
authors.forename: J M
authors.initials: JM
authors.lastname: Rowe-Jones
authors.forename: I S
authors.initials: IS
authors.lastname: Mackay
mesh_terms: D000328:Adult; D002908:Chronic Disease; D003550:Cystic Fibrosis / Q000150:complications*; D004724:Endoscopy; D005260:Female; D006801:Humans; D008297:Male; D009298:Nasal Polyps / Q000209:etiology / Q000601:surgery*; D011446:Prospective Studies; D012008:Recurrence; D012852:Sinusitis / Q000209:etiology / Q000601:surgery*