Case report: arthropathy as the presenting symptom in hereditary hemochromatosis.
Hemochromatosis is characterized by excessive absorption and subsequent deposition of iron in various organs and is prevalent in 1 out of 20,000 hospitalized patients. Most patients with hereditary hemochromatosis (HHC) become symptomatic between the ages of 50 and 60 years. Distinct forms of arthritis have been associated with HHC and may be the initial clinical manifestation in some patients. This is a case of a patient who had chronic hip and back pain and painless swelling over the knuckles. Radiographs revealed classical signs of HHC. Early recognition and prompt institution of phlebotomy can improve the outcome of patients with HHC.
Tanglao
E C
EC
Department of Medicine, Atlanta Veterans Affairs Medical Center, GA 30033, USA.
Stern
M A
MA
Agudelo
C A
CA
D000437:Alcoholism; D001168:Arthritis / Q000378:metabolism*; D001416:Back Pain / Q000175:diagnosis; D001842:Bone and Bones / Q000002:abnormalities; D030342:Genetic Diseases, Inborn / Q000235:genetics; D006432:Hemochromatosis / Q000150:complications / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D007501:Iron / Q000378:metabolism / Q000633:toxicity; D008297:Male; D008875:Middle Aged; D011871:Radiology
D007501:Iron