title: [Determination of free radical activity in workers at risk for styrene exposure].
abstract: The authors examined indicators of the effect of free radicals (MDA, SOD, GSHPx, selenium) in 38 workers exposed to styrene. They revealed a statistically significant (p < 0.01) correlation of SOD activity and the period of exposure to styrene and also a statistically significant correlation (p < 0.05) between urinary selenium excretion and the period of exposure to styrene as well as a statistically significant correlation (p < 0.01) between the MDA serum concentration and urinary selenium excretion. There is no statistically significant difference between the MDA plasma concentration among smokers and non-smokers, the SOD activity is significantly higher in non-smokers (p < 0.05). Based on the revealed findings the authors assume that free radicals may also play a part in the action of styrene on the organism.
authors.affiliation: Klinika pracovního lékarstvi, FN Plzen.
authors.forename: J
authors.initials: J
authors.lastname: Kohout
authors.forename: V
authors.initials: V
authors.lastname: Holecek
authors.forename: V
authors.initials: V
authors.lastname: Machartová
authors.forename: J
authors.initials: J
authors.lastname: Racek
authors.forename: Z
authors.initials: Z
authors.lastname: Jerábek
authors.forename: V
authors.initials: V
authors.lastname: Senft
mesh_terms: D000328:Adult; D005260:Female; D005609:Free Radicals / Q000378:metabolism*; D005979:Glutathione Peroxidase / Q000097:blood; D006801:Humans; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D016273:Occupational Exposure; D012307:Risk Factors; D012643:Selenium / Q000378:metabolism; D020058:Styrene; D013343:Styrenes / Q000009:adverse effects*; D013482:Superoxide Dismutase / Q000097:blood
chemical_list: D005609:Free Radicals; D013343:Styrenes; D020058:Styrene; D008315:Malondialdehyde; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D012643:Selenium
vernacular_title: Stanovení úcinku volných radikálů u pracovnků v riziku styrenu.