[The clinical usefulness of the combined use of inhaled beta 2-agonist and inhaled steroid in asthma].
Treatment with inhaled steroid has become increasingly important in asthma. However there are also many patients with asthma whose symptoms are uncontrolled by beclomethasone dipropionate (BDP) alone. For these patients we have tried the regular use of inhaled procaterol or inhaled fenoterol with BDP, and some of these patients have got good control. Recent studies show that, in patients whose asthma is inadequately controlled with BDP, better control can be achieved by adding inhaled long-acting beta 2-agonist rather than by doubling the dose of BDP. In the near future inhaled long-acting beta 2-agonist will be possible for clinical use in our country, and the combined use of it and BDP as preventive therapy will be the mainstay of treatment for patients with moderate-to-severe asthma.
Yamamoto
C
C
Second Department of Internal Medicine, Nara Medical University.
Narita
N
N
D000318:Adrenergic beta-Agonists / Q000008:administration & dosage*; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D001249:Asthma / Q000188:drug therapy*; D001507:Beclomethasone / Q000008:administration & dosage*; D018849:Controlled Clinical Trials as Topic; D003692:Delayed-Action Preparations; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005260:Female; D005280:Fenoterol / Q000008:administration & dosage*; D006801:Humans; D017265:Procaterol / Q000008:administration & dosage*
D000318:Adrenergic beta-Agonists; D000893:Anti-Inflammatory Agents; D003692:Delayed-Action Preparations; D005280:Fenoterol; D001507:Beclomethasone; D017265:Procaterol