title: The cumulative normalised rim/disc area ratio curve.
abstract: BACKGROUND
  The assessment of the cup of the optic disc depends, among other criteria, on the disc area. A small cup in a small optic disc can indicate an advanced glaucomatous lesion, while on the other hand a large cup in a large optic disc can be normal. Therefore, a cumulative normalised rim/disc area ratio curve could help to distinguish between glaucomatous and normal optic cups. The aim of our study was to calculate normalised rim/disc area ratio curve.
  
  
  METHODS
  Heidelberg Retina Tomograph examinations of the optic nerve head of 100 randomly selected eyes of 100 normal subjects were evaluated. We calculated the disc area-adjusted normalised rim/disc area ratio in sectors of 10 degrees. The 95th, 90th and 50th percentiles of each of the 36 sectors were displayed in descending order.
  
  
  RESULTS
  In relation to the normal percentile curves, it is possible to display an individual normalised rim/disc area ratio curve. We obtained such curves for a normal optic disc, optic nerve heads with moderate and advanced lesions and a small optic disc with glaucomatous damage.
  
  
  CONCLUSIONS
  We present a new display mode for the results of Heidelberg Retina Tomograph optic nerve head examination, which may be helpful for easy and reliable assessment of the local, diffuse and combined components of glaucomatous optic nerve head damage depending on optic disc size.
authors.affiliation: Department of Ophthalmology, University of Cologne, Köln, Germany.
authors.forename: K U
authors.initials: KU
authors.lastname: Bartz-Schmidt
authors.forename: A
authors.initials: A
authors.lastname: Sengersdorf
authors.forename: P
authors.initials: P
authors.lastname: Esser
authors.forename: P
authors.initials: P
authors.lastname: Walter
authors.forename: R D
authors.initials: RD
authors.lastname: Hilgers
authors.forename: G K
authors.initials: GK
authors.lastname: Krieglstein
mesh_terms: D000328:Adult; D005260:Female; D005901:Glaucoma / Q000473:pathology; D006801:Humans; D008297:Male; D018613:Microscopy, Confocal; D008875:Middle Aged; D008953:Models, Anatomic; D009898:Optic Disk / Q000033:anatomy & histology* / Q000473:pathology; D012016:Reference Values