title: [Effect of short- and long-time space flights on some biochemical and physical-chemical parameters of cosmonauts' blood].
abstract: The purpose of the present investigation was to look for original approaches to the analysis of physical-chemical (osmolality, sodium, potassium, and calcium concentrations) and hormonal (cortisol, aldosterone, vasopressin, parathormone, calcitonin) parameters of cosmonauts' serum. To this event, we investigated 35 cosmonauts who had made either short- (up to 8 days) or long-term (up to 366 days) space flights. The dispersion factor of these parameters was found to be a criterion for assessment of the reaction of human regulatory systems to extreme impacts. No evident correlative link between the preflight and postflight concentrations of inorganic serum components was established; however, there was a high correlation of parathormone and cortisol concentrations inferring the participation of these hormones in readaptation. Integral analysis of all the mineral and hormonal parameters of blood serum shapes them into something unique apt to change after flight. Our data alludes to the fact that the approaches used for evaluation of the data resulting from conventional techniques open up new possibilities for prediction of changes in and identification of the character of individual reaction of humans to the spaceflight factors.
authors.affiliation: State Scientific Center RF "Institute of Medical-Biological Problems".
authors.forename: A I
authors.initials: AI
authors.lastname: Grigorév
authors.forename: I M
authors.initials: IM
authors.lastname: Larina
authors.forename: V B
authors.initials: VB
authors.lastname: Noskov
authors.forename: V V
authors.initials: VV
authors.lastname: Menshtkin
authors.forename: I V
authors.initials: IV
authors.lastname: Natochkin
mesh_terms: D018480:Astronauts; D003627:Data Interpretation, Statistical; D004573:Electrolytes / Q000097:blood*; D004924:Escape Reaction / Q000502:physiology*; D006728:Hormones / Q000097:blood*; D006801:Humans; D009994:Osmolar Concentration; D010949:Plasma / Q000378:metabolism*; D012189:Retrospective Studies
chemical_list: D004573:Electrolytes; D006728:Hormones
vernacular_title: Vliianie neprodolzhitelńykh i dlitelńykh kosmicheskikh poletov na nekotorye biokhimicheskie i fiziko-khimicheskie parametry krovi kosmonavtov.