title: Combined Tc-99m MIBI and Tc-99m RBC for anatomic localization of ectopic mediastinal parathyroid adenomas.
abstract: Preoperative localization of abnormal parathyroid tissue in patients with persistent or recurrent hyperparathyroidism is recommended as a standard of care. A high percentage of these patients have ectopic tissue in the mediastinum. Tc-99m MIBI imaging alone for detection of ectopic parathyroid tissue in the mediastinum does not provide a sufficient number of anatomic landmarks, which makes communication regarding the exact location of any area of abnormal uptake difficult. We report the use of concomitant Tc-99m RBC and Tc-99m MIBI imaging for precise anatomic localization of ectopic mediastinal parathyroid tissue in 4 patients. It is thought that this combination of studies allows improved communication with referring physicians, surgeons, and radiologists for planning both surgical approach and correlative imaging studies. It is hoped that in the future this combination of studies may obviate the need for other imaging studies.
authors.affiliation: Department of Radiology, University of Florida College of Medicine, Gainesville, USA.
authors.forename: S T
authors.initials: ST
authors.lastname: Mastin
authors.forename: N M
authors.initials: NM
authors.lastname: Mancuso
authors.forename: J W
authors.initials: JW
authors.lastname: Kiser
authors.forename: M W
authors.initials: MW
authors.lastname: Nicole
authors.forename: W E
authors.initials: WE
authors.lastname: Drane
mesh_terms: D000236:Adenoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D000368:Aged; D002828:Choristoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D003142:Communication; D004912:Erythrocytes; D005260:Female; D013502:General Surgery; D006801:Humans; D006961:Hyperparathyroidism / Q000209:etiology; D006965:Hyperplasia; D007089:Image Enhancement; D007400:Interprofessional Relations; D008297:Male; D008477:Mediastinal Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D008875:Middle Aged; D010280:Parathyroid Glands / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D010282:Parathyroid Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D010347:Patient Care Planning; D011871:Radiology; D019275:Radiopharmaceuticals; D012008:Recurrence; D012017:Referral and Consultation; D013670:Sodium Pertechnetate Tc 99m; D013667:Technetium; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D019275:Radiopharmaceuticals; D013667:Technetium; D017256:Technetium Tc 99m Sestamibi; D013670:Sodium Pertechnetate Tc 99m