[Hypergammaglobulinemia D and familial urticaria in children].
OBJECTIVE
Recall the main elements suggesting the diagnosis of hyperimmunoglobulinemia D based on a family case of chronic urticaria.


METHODS
A boy and his mother presented the same signs of urticaria, fever and joint pain. Laboratory results showed an inflammatory syndrome in both. In the child, the first manifestations occurred during the age of one year. Hyperimmunoglobulinemia D was confirmed by persistently high serum levels.


CONCLUSIONS
The diagnosis of hyperimmunoglobuliemia D can be entertained in a child in a family with chronic urticaria. Fever, joint pain, digestive disorders and enlarged lymph nodes are suggestive and the diagnosis is confirmed by a clear elevation of serum IgD.
Bader-Meunier
B
B
Service de Pédiatrie générale, Hôpital Bicêtre, Le Kremlin Bicêtre.
Venencie
P Y
PY
Vieillefond
A
A
Le Touze
P
P
Dommergues
J P
JP
D018771:Arthralgia / Q000209:etiology; D002675:Child, Preschool; D005334:Fever / Q000209:etiology; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications*; D007072:Immunoglobulin D; D008297:Male; D012008:Recurrence; D014581:Urticaria / Q000150:complications / Q000235:genetics* / Q000276:immunology
D007072:Immunoglobulin D
Hyper-immunoglobulinémie D et urticaire familiale de l'enfant.