title: [Mutator genes from Saccharomyces cerevisiae. Interaction between HIM- and HSM-genes].
abstract: The interaction of six mutator genes of the yeast Saccharomyces cerevisiae with respect to UV-induced mutagenesis was studied. To this effect, double mutants with a genotype containing pairs of mutations at genes analyzed were synthesized. Analysis of the type of interaction of these mutations revealed four epistatic gene groups: (1) HIM1, HSM3, and HSM6; (2) HSM1; (3) HSM2; and (4) HIM2 and HIM3. The possible role of genes studied in different repair pathways of mispaired bases was discussed.
authors.forename: S V
authors.initials: SV
authors.lastname: Koval'tsova
authors.forename: L M
authors.initials: LM
authors.lastname: Gracheva
authors.forename: T A
authors.initials: TA
authors.lastname: Evstiukhina
authors.forename: I V
authors.initials: IV
authors.lastname: Fedorova
authors.forename: V G
authors.initials: VG
authors.lastname: Korolev
mesh_terms: D003470:Culture Media; D004260:DNA Repair; D005800:Genes, Fungal; D005838:Genotype; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D014466:Ultraviolet Rays
chemical_list: D003470:Culture Media
vernacular_title: Geny-mutatory drozhzheĭ Saccharomyces cerevisiae. Vzaimodeĭstvie mezhdu HIM- i HSM-genami.