title: [A familial case of keratoconus with corneal granular dystrophy].
abstract: We report a familial case of keratoconus with corneal granular dystrophy. The mother and first son have both keratoconus and corneal granular dystrophy and the second son has keratoconus alone. The keratoconus in this family is thought to be an autosomal dominant or an X-linked inheritance pattern. Granular dystrophy is an autosomal dominant inheritance. This familial case suggests that the gene loci of the two diseases are close together or have a close relationship.
authors.affiliation: Department of Ophthalmology Nihon University School of Medicine, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Mitsui
authors.forename: T
authors.initials: T
authors.lastname: Sakimoto
authors.forename: M
authors.initials: M
authors.lastname: Sawa
authors.forename: M
authors.initials: M
authors.lastname: Katami
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003317:Corneal Dystrophies, Hereditary / Q000150:complications* / Q000235:genetics*; D005192:Family Health; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D007640:Keratoconus / Q000150:complications* / Q000235:genetics*; D008297:Male