Gastric Helicobacter pylori infection as a cause of idiopathic Parkinson disease and non-arteric anterior optic ischemic neuropathy.
The mechanisms of pathogenesis for both idiopathic Parkinson disease and non-arteritic anterior optic ischemic neuropathy are unknown. A study has shown that, in both diseases, there is a higher prevalence of gastrointestinal ulcers than in age- and sex-matched controls or than in the reported rates for the general population. It is proposed that gastric Helicobacter pylori infection may be a cause of both these diseases.
Altschuler
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UC San Diego School of Medicine 0606, La Jolla 92093-0109, USA.
D004381:Duodenal Ulcer / Q000453:epidemiology; D005260:Female; D016481:Helicobacter Infections / Q000150:complications* / Q000503:physiopathology*; D016480:Helicobacter pylori; D006801:Humans; D008297:Male; D008954:Models, Biological; D018917:Optic Neuropathy, Ischemic / Q000209:etiology* / Q000503:physiopathology; D010300:Parkinson Disease / Q000209:etiology* / Q000503:physiopathology; D015995:Prevalence; D013276:Stomach Ulcer / Q000453:epidemiology