Synthesis and activity of N epsilon-aminocaproyl-L-norleucine derivatives.
Five new derivatives of epsilon-aminocaproyl-L-norleucine were synthesized. Antifibrinolytic and anticaseinolytic activities were tested. All tested compounds were inhibitors of plasmin.
Midura-Nowaczek
K
K
Institute of Chemistry, Branch of Warsaw University in Białystok, Poland.
Bruzgo
I
I
Roszkowska-Jakimiec
W
W
Worowski
K
K
D015119:Aminocaproic Acid / Q000737:chemistry; D000933:Antifibrinolytic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002364:Caseins / Q000378:metabolism*; D004024:Dicyclohexylcarbodiimide / Q000737:chemistry; D015195:Drug Design; D005341:Fibrinolysin / Q000378:metabolism*; D009646:Norleucine / Q000031:analogs & derivatives* / Q000737:chemistry*; D013329:Structure-Activity Relationship; D014230:Triazoles / Q000737:chemistry
D000933:Antifibrinolytic Agents; D002364:Caseins; C103892:N(6)-aminocaproylnorleucine; D014230:Triazoles; D004024:Dicyclohexylcarbodiimide; D009646:Norleucine; C011852:1-hydroxybenzotriazole; D005341:Fibrinolysin; D015119:Aminocaproic Acid