title: Case study: withdrawal syndrome in adolescent chronic cannabis users.
abstract: Cannabis use is common among adolescents and has recently been increasing, especially among young teenagers. Whether the reduction of cannabis in chronic heavy users results in a clinically significant withdrawal syndrome is controversial. This article presents three case vignettes supporting the view that chronic cannabis use by adolescents may result in a clinically significant withdrawal syndrome and that the associated physiological symptoms directly contribute to the persistent use of the substance.
authors.affiliation: Royal Ottawa Hospital, Ontario, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Duffy
authors.forename: R
authors.initials: R
authors.lastname: Milin
mesh_terms: D000293:Adolescent; D005260:Female; D006801:Humans; D007508:Irritable Mood; D008297:Male; D002189:Marijuana Abuse / Q000150:complications*; D007319:Sleep Initiation and Maintenance Disorders / Q000139:chemically induced; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy / Q000503:physiopathology*