Epstein-Barr virus associated graft failure following heart/lung transplantation.
A case is described of late pulmonary graft failure in a heart/lung transplant recipient. The major characteristics were alveolar fibrosis and a restrictive physiological deficit. Epstein-Barr virus was implicated as an aetiological agent using immunohistochemical analysis and by a response to treatment with ganciclovir.
Egan
J J
JJ
North West Lung Centre, Wythenshawe Hospital, Manchester.
Stewart
J P
JP
Hasleton
P S
PS
Yonan
N
N
Bishop
P
P
Arrand
J R
JR
Rahman
A N
AN
Carroll
K B
KB
Woodcock
A A
AA
D000328:Adult; D005260:Female; D006084:Graft Rejection / Q000821:virology*; D016041:Heart-Lung Transplantation; D006566:Herpesviridae Infections / Q000150:complications*; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D011658:Pulmonary Fibrosis / Q000821:virology; D014412:Tumor Virus Infections / Q000150:complications*