title: [Suppression of immunological response in a newborn with congenital cytomegalovirus infection: diagnostic difficulties].
abstract: A newborn with symptoms of congenital cytomegalovirus infection (interuterine dystrophy, thrombocytopenia, leukopenia, hepatosplenomegaly, chronic pneumonia, pleocytosis in CSF) is described in whom tests for specific anti- CMV-IgM antibodies were negative. Changes typical for cytomegaloviral infection were found on autopsy. The authors discuss the difficulties in interpreting various serologic tests (CFT, anti-CMV IgM) in congenital infections, suggesting the necessity of introducing new diagnostic methods for better diagnosis and treatment.
authors.affiliation: Zakład Propedeutyki Pediatrii Akademii Medycznej w Lublinie.
authors.forename: W
authors.initials: W
authors.lastname: Furmaga-Jabłońska
authors.forename: B
authors.initials: B
authors.lastname: Korczowski
authors.forename: B
authors.initials: B
authors.lastname: Maksymiuk
mesh_terms: D001921:Brain / Q000648:ultrastructure; D003586:Cytomegalovirus Infections / Q000151:congenital* / Q000175:diagnosis* / Q000276:immunology; D017809:Fatal Outcome; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology; D002479:Inclusion Bodies / Q000648:ultrastructure; D007231:Infant, Newborn; D007668:Kidney / Q000648:ultrastructure; D008168:Lung / Q000648:ultrastructure; D008297:Male
chemical_list: D007075:Immunoglobulin M
vernacular_title: Supresja odpowiedzi immunologicznej w przebiegu cytomegalii wrodzonej u noworodka--trudności diagnostyczne.