[Bacteremia and endocarditis caused by Streptococcus bovis in patients with alcoholic hepatopathy without evidence of colonic pathology].
The association of Streptococcus bovis bacteremia and endocarditis with colonic pathology, mainly neoplastic, is well known. Its relationship with liver disease without evidence of gastrointestinal disease has been rarely described. To analyze the association between S. bovis infection and liver disease, positive blood cultures for this microorganism in hospitalized patients in the Internal Medicine and Gastroenterology Departments from December 1993 until October 1995, have been reviewed. Three cases of S. bovis infection (one bacteremia, two endocarditis) were found. Alcoholic liver disease was diagnosed in all three patients, with associated hepatitis C virus in one of them. Colonic pathology was excluded by colonoscopy and/or barium enema. Other gastrointestinal disorders were excluded by means of gastroscopy, barium gastrointestinal study and abdominal ultrasonography. Antibiotic therapy was based in betalactamics, with associated aminoglycoside in two cases. One patient needed aortic and mitral valve replacement and another one needed orthotopic liver transplantation. No new gastrointestinal pathology emerged in the follow-up (5-23 months). Cases of S. bovis bacteremia and endocarditis should be screened not also for colonic pathology, but also for liver disease, particularly in alcoholics.
Castroagudín
J F
JF
Complejo Hospitalario Universitario, Santiago de Compostela, Servicio de Aparato Digestivo.
Lorenzo Solar
M
M
Martínez Rey
C
C
Brage Varela
A
A
Torre
J A
JA
González Quintela
A
A
D000328:Adult; D016470:Bacteremia / Q000188:drug therapy / Q000382:microbiology*; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D008108:Liver Diseases, Alcoholic / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000188:drug therapy; D016985:Streptococcus bovis
Bacteriemia y endocarditis por Streptococcus bovis en pacientes con hepatopatía alcohólica sin evidencia de patología colónica.