title: [Effects of small fluxes of heavy charged particles on neurons of the rats' cerebral cortex in delayed periods following irradiation].
abstract: Dystrophic changes in neurons of the sensorimotor cortex of rat's brain in delayed periods following exposure to small fluxes, i.e. 104 and 105 particles/cm2, of accelerated carbon, fluorine, and oxygen ions with an energy of 300 MeV/nucleon and 137Cs gamma-rays at a dose of 1.0 Gy were quantitatively analyzed. Some structural changes of varying degree including death of a part of neurons were observed; however, most of the cells looked unaltered. Glial elements and small blood vessels also developed a reaction. Dynamics of the morphologic changes was studied. Higher effectiveness of small fluxes of heavy charged particles versus gamma-radiation at a dose of 1.0 Gy and dependence of the depth of structural disorders on linear energy transfer were demonstrated.
authors.affiliation: State Scientific Center RF, "Institute of Medico-Biological Problems".
authors.forename: N N
authors.initials: NN
authors.lastname: Budennaia
mesh_terms: D000818:Animals; D002540:Cerebral Cortex / Q000473:pathology / Q000528:radiation effects*; D002588:Cesium Radioisotopes; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005500:Follow-Up Studies; D018499:Linear Energy Transfer; D009474:Neurons / Q000473:pathology / Q000528:radiation effects*; D010315:Particle Accelerators; D011522:Protons; D051381:Rats; D017208:Rats, Wistar
chemical_list: D002588:Cesium Radioisotopes; D011522:Protons
vernacular_title: Vliianie malykh potokov tiazhelykh zariazhennykh chastits na neirony kory golovnogo mozga krys v otdalennye sroki posle oblucheniia.