title: Ameloblastoma with prominent ossification in the mandible of a dog.
abstract: A rare case of ameloblastoma with prominent stromal ossification in an 8-year-old female dog was studied. A bony mass recurred rapidly in the right mandible at the first molar region. Histopathologic examination revealed the lesion to be an atypical variant of ameloblastoma. Epithelial cells showed marked cell atypia, and mitotic figures were rather common. The collagenous stroma was abundant, with prominent formation of bone trabecular rimmed by active osteoblasts. The tumor was highly proliferative and aggressive, and thought to be malignant in nature.
authors.affiliation: Department of Veterinary Pathology, Gifu University, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Sakai
authors.forename: T
authors.initials: T
authors.lastname: Yanai
authors.forename: K
authors.initials: K
authors.lastname: Yoshida
authors.forename: T
authors.initials: T
authors.lastname: Iwasaki
authors.forename: H
authors.initials: H
authors.lastname: Fujioka
authors.forename: J
authors.initials: J
authors.lastname: Ota
authors.forename: K
authors.initials: K
authors.lastname: Isowa
authors.forename: T
authors.initials: T
authors.lastname: Masegi
mesh_terms: D000564:Ameloblastoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D002455:Cell Division / Q000502:physiology; D004283:Dog Diseases / Q000175:diagnosis / Q000473:pathology*; D004285:Dogs; D004848:Epithelium / Q000737:chemistry / Q000473:pathology; D005260:Female; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008334:Mandible / Q000737:chemistry / Q000473:pathology; D008339:Mandibular Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D009999:Ossification, Heterotopic / Q000473:pathology / Q000662:veterinary*; D010006:Osteoblasts / Q000473:pathology
chemical_list: D007633:Keratins