Phototherapy of eczema.
Several studies have shown a beneficial effect of ultraviolet radiation on eczema, especially atopic dermatitis. The action spectrum lies at higher wavelengths compared with psoriasis. UVAB seems to be superior to UVB and best suited for mild to moderate cases. From a carcinogenic point of view, the therapy seems safe and the doses are low compared with UVB treatment of psoriasis. UVA-1 therapy seems to be a promising new alternative, especially for more severe cases. High-dose regimens work well but the hazards are not yet fully elucidated. The very high dosage regimens should be reserved for very resistant cases where lower doses have been tried but proven inadequate. PUVA is also very effective, but due to the long-term hazards it should be reserved for the most severe cases of atopic dermatitis.
Larkö
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Department of Dermatology, University of Göteborg, Sahlgrenska Hospital, Sweden.
D003876:Dermatitis, Atopic / Q000532:radiotherapy; D004485:Eczema / Q000188:drug therapy / Q000532:radiotherapy*; D006801:Humans; D011701:PUVA Therapy; D011879:Radiotherapy Dosage; D014467:Ultraviolet Therapy / Q000009:adverse effects