The cerebellum and cognitive function: implications for rehabilitation.
OBJECTIVE
To characterize the cognitive effects of isolated cerebellar lesions.


METHODS
Review of two inpatient cases.


METHODS
The rehabilitation unit of a tertiary general hospital.


METHODS
Two patients with acute ischemic strokes who had solitary cerebellar infarcts.


METHODS
Assessment with standard neuropsychological tests. Scores were compared with patients' premorbid levels and standardized test norms. A classical conditioning eyeblink paradigm was performed.


METHODS
Neuropsychological measures of intellectual and executive functions, learning and memory, visual-spatial abilities, language functioning, fine motor speed, and dexterity.


RESULTS
Test findings suggested lesion-associated deficits in higher aspects of cognition (visuospatial reasoning, verbal and visual memory, and intellectual and executive functions). These functions are not usually associated with the fundamentally motoric role of the cerebellum.


CONCLUSIONS
(1) Lesions in the cerebellum can be associated with impairments in higher cognitive functioning. (2) Such effects may be severe enough for a diagnosis of dementia under current diagnostic criteria. (3) These rehabilitation patients may benefit from comprehensive cognitive examination to determine if cognitive effects will detract from their participation. (4) Further research is needed to localize which cerebellar areas affect which cognitive abilities.
Chafetz
M D
MD
Department of Psychiatry, Baylor College of Medicine, Houston, TX 77030, USA.
Friedman
A L
AL
Kevorkian
C G
CG
Levy
J K
JK
D000368:Aged; D002531:Cerebellum / Q000098:blood supply / Q000503:physiopathology*; D002561:Cerebrovascular Disorders / Q000503:physiopathology / Q000523:psychology*; D003072:Cognition Disorders / Q000503:physiopathology*; D005260:Female; D006801:Humans; D014854:Lateral Medullary Syndrome / Q000503:physiopathology / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests