title: [Active forms of oxygen: cytotoxic effects and methodological approaches to laboratory control of liver lesions (literature review)].
abstract: The injurious effects of active oxygen forms (AOF) on the cell caused by destruction of its membranous structures and impairment of their functional characteristics are discussed. Disorders of the processes of formation and inactivation of AOF in hepatocytes may be the metabolic mechanisms mediating the status and development of the pathological process in the liver. The problem of prospective approaches to assessing chronic diseases of the liver at the level of "free-radical pathology" is discussed.
authors.forename: B N
authors.initials: BN
authors.lastname: Matiushin
authors.forename: A S
authors.initials: AS
authors.lastname: Loginov
mesh_terms: D001706:Biopsy; D002908:Chronic Disease; D006801:Humans; D015227:Lipid Peroxidation; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D008103:Liver Cirrhosis / Q000378:metabolism / Q000473:pathology; D008107:Liver Diseases / Q000378:metabolism* / Q000473:pathology; D013482:Superoxide Dismutase / Q000378:metabolism; D013481:Superoxides / Q000378:metabolism* / Q000633:toxicity
chemical_list: D013481:Superoxides; D013482:Superoxide Dismutase
vernacular_title: Aktivnye formy kisloroda: tsitoksicheskoe deĭstvie i metodicheskie podkhody k laboratornomu kontroliu pri porazhenii pecheni (obzor literatury).