title: Polyclonal lymphoid tumor of the choroid plexus presenting as an intraventricular mass in a young gorilla.
abstract: An unusual lymphoid lesion with reactive germinal centers, occurring in the choroid plexus of a young gorilla, is reported. It presented as a large mass in the lateral ventricle with hydrocephalus and neurological symptoms. A work-up did not reveal any underlying cause for this lesion. No similar lesion of the choroid plexus has been reported in either human or veterinary literature. Histological work-up, including flow cytometry, gene rearrangement studies and T and B cell markers, favored the lesion being a non-neoplastic lymphoid proliferation of unknown etiology. The prognosis is unknown, although, following complete removal, the animal is well and free of tumor at the time of this report.
authors.affiliation: Section of Neuropathology, Loyola University Medical Center, Maywood, IL 60153, USA.
authors.forename: C
authors.initials: C
authors.lastname: Thomas
authors.forename: D
authors.initials: D
authors.lastname: Anderson
authors.forename: M
authors.initials: M
authors.lastname: Grigg-Damberger
authors.forename: M
authors.initials: M
authors.lastname: Gujrati
authors.forename: J M
authors.initials: JM
authors.lastname: Lee
authors.forename: R
authors.initials: R
authors.lastname: Murnane
authors.forename: G
authors.initials: G
authors.lastname: Dizikes
authors.forename: R
authors.initials: R
authors.lastname: Radvany
authors.forename: T
authors.initials: T
authors.lastname: Walsh
authors.forename: T P
authors.initials: TP
authors.lastname: Meehan
mesh_terms: D000818:Animals; D018420:Ape Diseases / Q000175:diagnosis* / Q000473:pathology; D002551:Cerebral Ventricle Neoplasms / Q000662:veterinary*; D002648:Child; D016545:Choroid Plexus Neoplasms / Q000473:pathology / Q000662:veterinary*; D003937:Diagnosis, Differential; D006071:Gorilla gorilla; D006801:Humans; D008206:Lymphatic Diseases / Q000473:pathology / Q000662:veterinary*; D008297:Male