[Acute interstitial nephropathy induced by vancomycin].
The authors report a case of tubulo-interstitial nephritis with acute renal failure due to vancomycin used to treat a patient with enterococcus endocarditis. Rechallenge with vancomycin several days after stopping the drug resulted in the appearance of a maculopapular rash and rapid onset of acute oligo-anuric renal failure. Renal biopsy revealed acute interstitial nephritis. This feature is suggestive of cellular mediated hypersensitivity.
Azar
R
R
Service de néphrologie, Centre hospitalier général, Dunkerque.
Bakhache
E
E
Boldron
A
A
D000208:Acute Disease; D058186:Acute Kidney Injury / Q000139:chemically induced; D000368:Aged; D004697:Endocarditis, Bacterial / Q000188:drug therapy; D016983:Enterococcus; D005260:Female; D006801:Humans; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000473:pathology; D014640:Vancomycin / Q000009:adverse effects* / Q000627:therapeutic use
D014640:Vancomycin
Néphropathie interstitielle aiguë induite par la vancomycine.