[Detection of multi-focal breast carcinoma using 2[18F] fluoro-deoxy-D-glucose positron emission tomography (FDG-PET)].
The elevated rate of glycolysis in malignomas compared to normal tissues can be visualised by positron-emission-tomography (PET) using 2[18F]fluoro-deoxy-D-Glucose (FDG). Based on the case of a 38-year old woman with multifocal carcinoma of the right breast (pT1 c pN0 M0, G2) as a vehicle, we describe a FDG-PET procedure which is comparable to established methods of nuclear medicine (e.g. bone scan) with regard to patient's burden and time consumption and could be used on a routine basis. This technique allowed correct assessment of suspicious breast findings and visualised multifocal growth of a tumour which was judged to be a unifocal breast cancer by conventional methods of clinical examination, mammography and ultrasound.
Scharl
A
A
Klinik und Poliklinik für Frauenheilkunde und Geburtshilfe, Universität zu Köln.
Scheidhauer
K
K
Pietrzyk
U
U
Göhring
U J
UJ
Schomäcker
K
K
D000328:Adult; D001786:Blood Glucose / Q000378:metabolism*; D001940:Breast / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D003847:Deoxyglucose / Q000031:analogs & derivatives; D003937:Diagnosis, Differential; D005260:Female; D005348:Fibrocystic Breast Disease / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D019788:Fluorodeoxyglucose F18; D006019:Glycolysis / Q000502:physiology; D006801:Humans; D009367:Neoplasm Staging; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging* / Q000473:pathology / Q000503:physiopathology; D014055:Tomography, Emission-Computed / Q000379:methods*
D001786:Blood Glucose; D019788:Fluorodeoxyglucose F18; D003847:Deoxyglucose
Nachweis der Multifokalität eines Mammakarzinoms durch 2[18F] Fluor-Deoxy-D-Glukose Positronen-Emissions-Tomographie (FDG-PET).