Translocation t(15;17) in acute myelogenous leukemia with atypical megakaryoblastic features: diagnostic, clinical, and therapeutic implications.
We describe the first reported case of acute myelogenous leukemia with characteristics of megakaryoblastic differentiation and the t(15;17) chromosomal translocation, which has been associated with promyelocytic leukemia. The diagnostic, clinical, and therapeutic implications are discussed.
Morgan
D L
DL
Department of Pathology, Texas Tech University, Lubbock, USA.
Dunn
D M
DM
Cobos
E
E
Keung
Y K
YK
McConnell
T S
TS
Tonk
V
V
D000293:Adolescent; D005260:Female; D006801:Humans; D007621:Karyotyping; D007947:Leukemia, Megakaryoblastic, Acute / Q000473:pathology; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000473:pathology*; D008533:Megakaryocytes / Q000473:pathology*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology