title: Band 3 in cell volume regulation in fish erythrocytes.
abstract: Erythrocytes of the skate (Raja erinacea) demonstrate a regulatory volume decrease response when exposed to hypotonic stress by releasing taurine and other organic osmolytes. We review the transport characteristics, physical changes and signaling pathways of a volume-activated osmolyte channel associated with band 3 in skate red blood cells that can be distinguished from anion channels and is separate from the anion exchanger function of band 3.
authors.affiliation: Department of Physiology, Brown University, Providence, RI 02912, USA.
authors.forename: D F
authors.initials: DF
authors.lastname: Perlman
authors.forename: M W
authors.initials: MW
authors.lastname: Musch
authors.forename: L
authors.initials: L
authors.lastname: Goldstein
mesh_terms: D000818:Animals; D001457:Anion Exchange Protein 1, Erythrocyte / Q000378:metabolism; D048429:Cell Size; D004912:Erythrocytes / Q000166:cytology* / Q000378:metabolism; D007473:Ion Channels / Q000378:metabolism*; D015398:Signal Transduction; D012860:Skates, Fish / Q000097:blood*; D013654:Taurine / Q000378:metabolism; D014882:Water-Electrolyte Balance
chemical_list: D001457:Anion Exchange Protein 1, Erythrocyte; D007473:Ion Channels; D013654:Taurine