title: Improvement of fatigue and acceleration of recovery from stress-induced deficient sexual behavior in mice following oral administration of soft-shelled turtle powder.
abstract: Effects of oral administration of cryomilled powder of the soft-shelled turtle (SST powder) on forced-exercise performance and stress-induced reduction in sexual and learning behavior were studied in mice. In the fatigue-preventive experiment, the SSt powder was administered orally to mice which were forced to climb a descending rope for 60 min a day. The treatment significantly improved the daily performance of the mice. In the stress recovery experiment, male mice were hanged from the tail and forced to swim using their fore paws for 30 to 60 min everyday. Stress significantly reduced sexual behavior and memory retrieval (step down test). Daily oral administration of the SST powder significantly attenuated this decline in sexual behavior. However, the effects on memory retrieval were not statistically significant. These results suggest that administration of SST powder attenuates fatigue and accelerates recovery from stress in mice.
authors.affiliation: Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, University of Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Feng
authors.forename: N
authors.initials: N
authors.lastname: Matsuki
authors.forename: H
authors.initials: H
authors.lastname: Saito
mesh_terms: D000284:Administration, Oral; D000818:Animals; D005221:Fatigue / Q000517:prevention & control*; D007858:Learning / Q000187:drug effects; D008297:Male; D008516:Medicine, Chinese Traditional; D051379:Mice; D011208:Powders; D012726:Sexual Behavior, Animal / Q000187:drug effects*; D013312:Stress, Physiological / Q000523:psychology*; D014426:Turtles
chemical_list: D011208:Powders