Is diabetic heart muscle disease related to cardiac ischemia or autonomic neuropathy?
Whether diabetic heart muscle disease is related to cardiac ischemia or autonomic neuropathy was investigated employing thallium-201 and [123I]meta-iodobenzylguanidine (MIBG) myocardial scintigraphy. Among ischemic hearts, displayed by TI201 scintigraphy, a distinctly dilated and hypokinetic left ventricle could not be detected. In autonomically denervated hearts, however, well demonstrated by MIBG imaging, distinct dysfunction was found. But, even in these hearts, interacting effects of some concomitant complications could not be excluded.
Izumi
T
T
Department of Internal Medicine and Cardiology, Kitasato University School of Medicine, Sagamihara, Japan.
Tsuda
T
T
Kuwano
H
H
Ishiguro
J
J
D019797:3-Iodobenzylguanidine; D001342:Autonomic Nervous System Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D003287:Contrast Media; D048909:Diabetes Complications; D004452:Echocardiography; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging; D006329:Heart Conduction System; D006331:Heart Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D006801:Humans; D007462:Iodobenzenes; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging / Q000209:etiology*; D013793:Thallium; D015899:Tomography, Emission-Computed, Single-Photon
D003287:Contrast Media; D007462:Iodobenzenes; D019797:3-Iodobenzylguanidine; D013793:Thallium