title: Dimensions of the pediatric crystalline lens: implications for intraocular lenses in children.
abstract: As surgeons gain more experience with the implantation of posterior chamber intraocular lenses (IOLs) into the capsular bag in children, the minimum age for which implantation is advised may continue to be lowered. Accurate sizing of an IOL intended for in-the-bag fixation may depend on knowledge of the size of the capsular bag. In order to develop a growth curve for the normal crystalline lens and hence the capsular bag, 50 pediatric autopsy eyes ranging in age from 1 day to 16 years were obtained postmortem and measured within 24 hours after enucleation. Mean crystalline lens diameter was 6.00 mm at birth, 6.80 mm at 2 months, 7.1 mm at 3 months, 7.66 mm at 6 to 9 months, 8.4 mm at 21 months, 8.5 mm at 2 to 5 years, and 9.3 mm at 16 years. The post-lensectomy capsular bag size at each respective age is 1 mm larger. While age was a predictor of crystalline lens size, corneal diameter and globe axial length were better predictors of crystalline lens size. These data and accompanying linear regressions may be helpful in designing appropriate IOLs for pediatric patients.
authors.affiliation: N. Edgar Miles Center for Pediatric Ophthalmology, Storm Eye Institute, Charleston, SC, USA.
authors.forename: E C
authors.initials: EC
authors.lastname: Bluestein
authors.forename: M E
authors.initials: ME
authors.lastname: Wilson
authors.forename: X H
authors.initials: XH
authors.lastname: Wang
authors.forename: P F
authors.initials: PF
authors.lastname: Rust
authors.forename: D J
authors.initials: DJ
authors.lastname: Apple
mesh_terms: D000293:Adolescent; D000375:Aging / Q000502:physiology; D002102:Cadaver; D002648:Child; D002675:Child, Preschool; D003315:Cornea / Q000033:anatomy & histology; D005544:Forecasting; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007908:Lens, Crystalline / Q000033:anatomy & histology* / Q000254:growth & development; D007910:Lenses, Intraocular; D012044:Regression Analysis