title: [The level of embryonic antigens in the blood serum and cerebrospinal fluid of neuro-oncological patients].
abstract: The levels of embryonic antigens (cancer embryonic antigen, alpha-fetoprotein, beta-chorionic gonadotropin were measured in the serum, spinal fluid, the cystic fluid of tumor 83 of neuro-oncological patients. It was found that the blood concentrations of cancer embryonic antigen and alpha-fetoprotein were not generally related to the degree of malignancy and the blood level of beta-chorionic gonadotropin decreased with the higher degree of tumor anaplasia. The high content of beta-chorionic gonadotropin in the spinal fluid suggests its origin from a brain tumor. The fatal postoperative outcome was noted in patients having high preoperative serum levels of alpha-fetoprotein and cancer embryonic antigen with simultaneous much higher concentrations of alpha-fetoprotein in the serum than those in the spinal fluid.
authors.forename: V A
authors.initials: VA
authors.lastname: Rudenko
authors.forename: N I
authors.initials: NI
authors.lastname: Lisianyĭ
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Grinevich
authors.forename: M B
authors.initials: MB
authors.lastname: Burkatovskaia
authors.forename: L G
authors.initials: LG
authors.lastname: Iugrinova
mesh_terms: D000708:Anaplasia / Q000175:diagnosis / Q000601:surgery; D001254:Astrocytoma / Q000175:diagnosis* / Q000601:surgery; D014408:Biomarkers, Tumor / Q000032:analysis*; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000601:surgery; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D006063:Chorionic Gonadotropin / Q000032:analysis*; D005909:Glioblastoma / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007124:Immunoenzyme Techniques / Q000706:statistics & numerical data; D007432:Intraoperative Period; D011184:Postoperative Period; D013997:Time Factors; D000509:alpha-Fetoproteins / Q000032:analysis*
chemical_list: D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins
vernacular_title: Soderzhanie émbrional'nykh antigenov v syvorotke krovi i likvore neĭroonkologicheskikh bol'nykh.