title: Asthmatic reactions after nasal allergen provocation.
abstract: Three bronchoconstrictive responses associated with acute rhinitis and occurring in two patients were observed among 400 nasal allergen challenges. Causative substances were birch pollen, Dermatophagoides pteronyssinus and HSA-conjugated pyromellitic dianhydride. Both subjects showed bronchial hyperreactivity and immediate-type sensitization to these allergens. It is concluded that bronchoobstruction nearly occurs in nasal allergen challenges. The underline pathophysiological mechanism remains unclear.
authors.affiliation: Medical Department, Ruhr University of Bochum, Germany.
authors.forename: X
authors.initials: X
authors.lastname: Baur
mesh_terms: D000208:Acute Disease; D000328:Adult; D000485:Allergens / Q000276:immunology*; D039741:Antigens, Dermatophagoides; D001249:Asthma / Q000276:immunology*; D001565:Benzoates / Q000276:immunology; D006023:Glycoproteins / Q000276:immunology; D006801:Humans; D008297:Male; D009299:Nasal Provocation Tests / Q000009:adverse effects*; D011058:Pollen / Q000276:immunology; D012220:Rhinitis / Q000276:immunology; D012709:Serum Albumin / Q000276:immunology; D014197:Trees / Q000276:immunology
chemical_list: D000485:Allergens; D039741:Antigens, Dermatophagoides; D001565:Benzoates; D006023:Glycoproteins; D012709:Serum Albumin; C012019:pyromellitic dianhydride