title: [Intra-arterial thrombolysis in peripheral bypass and arterial occlusions. Results and predictive factors for thrombolysis].
abstract: The purpose of the study was to reveal the association between successful intra-arterial thrombolysis in peripheral arterial and graft occlusions and the following factors: sex, age, symptoms, duration of symptoms, length of occlusion, conduit type, runoff and catheter localisation. Forty-six patients were treated with continuous intra-arterial infusion of streptokinase. Twelve patients were given tissue plaminogen activator (tPA). In the streptokinase-group successful lysis was achieved in 27 of 46 patients (59%). A significant association was found between successful thrombolysis and good runoff (p < 0.01). Catheter position above the occlusion resulted in lysis in only 1 of 11 patients. Lysis was achieved in nine of 12 patients (75%) treated with tPA. In this study, good runoff and intrathrombotic infusion were almost prerequisites for obtaining a positive immediate outcome. Other factors were less important.
authors.affiliation: Røntgenavdelingen, Aker sykehus, Oslo.
authors.forename: G
authors.initials: G
authors.lastname: Sandbaek
authors.forename: L E
authors.initials: LE
authors.lastname: Staxrud
authors.forename: L
authors.initials: L
authors.lastname: Rosén
authors.forename: D
authors.initials: D
authors.lastname: Bay
authors.forename: M
authors.initials: M
authors.lastname: Stiris
authors.forename: T
authors.initials: T
authors.lastname: Gjølberg
mesh_terms: D000368:Aged; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D010960:Plasminogen Activators / Q000008:administration & dosage*; D011859:Radiography; D013300:Streptokinase / Q000008:administration & dosage*; D013923:Thromboembolism / Q000000981:diagnostic imaging / Q000188:drug therapy; D015912:Thrombolytic Therapy / Q000379:methods; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage*
chemical_list: D005343:Fibrinolytic Agents; D013300:Streptokinase; D010960:Plasminogen Activators; D010959:Tissue Plasminogen Activator
vernacular_title: Intraarteriell trombolyse ved perifere bypass- og arterieokklusjoner. Resultater og prediktive faktorer for trombolyse.