Cytogenetic study of neuroendocrine carcinoma of Merkel cells.
We describe the cytogenetic study of a neuroendocrine tumor of Merkel cells which appeared in a patient following a heart transplant. An abnormal karyotype was observed in a metastatic lymph node. The abnormality includes two markers derived from the long arm of chromosome 1, while maintaining two normal chromosomes 1.
Vázquez-Mazariego
Y
Y
Medical Genetics Department, Hospital Ramón y Cajal, Madrid, Spain.
Vallcorba
I
I
Ferro
M T
MT
López-Yarto
A
A
García-Sagredo
J M
JM
Cabello
P
P
Resino
M
M
Muñoz
R
R
Mayayo
M
M
San Román
C
C
D000782:Aneuploidy; D001132:Arm; D015266:Carcinoma, Merkel Cell / Q000235:genetics*; D002878:Chromosomes, Human, Pair 1 / Q000235:genetics*; D005819:Genetic Markers; D016027:Heart Transplantation; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D008297:Male; D008875:Middle Aged; D012878:Skin Neoplasms / Q000235:genetics*
D005819:Genetic Markers