[Bronchiolitis obliterans organizing pneumonia (BOOP) after allogeneic bone marrow transplantation].
We report a patient who underwent allogeneic bone marrow transplantation for ALL. The patient presented low grade fever, cough and dyspnea at day 3 after after bone marrow transplantation. Imaging studies showed bilateral patchy infiltrates on chest X-ray and chest CT. Though treated by antibiotics, chest auscultation recognized marked bilateral inspiratory crackles. Transbronchial lung biopsy performed on day 34 showed bronchiolitis obliterans and an organizing interstitial pneumonia. The patient was treated with methylprednisolone and follow up computed tomography findings improved.
Nakayama
M
M
Department of Hematology/Oncology Institute of Medical Science, University of Tokyo.
Takahashi
S
S
Inoue
T
T
Nagamura
F
F
Setoyama
M
M
Ooi
J
J
Takahashi
T
T
Oshima
Y
Y
Miyamoto
K
K
Uemura
N
N
Shindo
E
E
Tajika
K
K
Yanagisawa
K
K
Nagayama
H
H
Okamoto
S
S
Tojo
A
A
Tani
K
K
Ozawa
K
K
Asano
S
S
Wakabayashi
T
T
Sato
N
N
Ichinose
Y
Y
Toyama
K
K
Saito
H
H
D000284:Administration, Oral; D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D018549:Cryptogenic Organizing Pneumonia / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D008775:Methylprednisolone / Q000008:administration & dosage; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy
D008775:Methylprednisolone