title: [The immunity of patients with keratoconus].
abstract: Cellular and humoral immunity parameters were studied in patients with keratoconus at different stages, aged 14 to 49 years. The results showed the immune homeostasis to be impaired in patients with local involvement of the cornea. At a total system's level the patients developed shifts in the relative content of T-lymphocytes and their subpopulations, dysimmunoglubulinemia with increased levels of immunoglobulins of the primary immune response in the blood serum, high levels of the C3 and C4 components with a reduction of the total hemolytic activity of the complement, increased levels of NBT-positive and phagocytic cells, and a decrease of the activity of serum lysozyme.
authors.affiliation: Department of Ophthalmology of Uralsk Advanced Training Institute for Doctors, Cheliabinsk
authors.forename: L N
authors.initials: LN
authors.lastname: Tarasova
authors.forename: E N
authors.initials: EN
authors.lastname: Gorskova
authors.forename: S N
authors.initials: SN
authors.lastname: Teplova
authors.forename: E N
authors.initials: EN
authors.lastname: Sevostíanov
mesh_terms: D000293:Adolescent; D000328:Adult; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood*; D007640:Keratoconus / Q000097:blood / Q000276:immunology*; D018655:Lymphocyte Count; D008875:Middle Aged; D009113:Muramidase / Q000097:blood; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D007070:Immunoglobulin A; D007075:Immunoglobulin M; D009113:Muramidase
vernacular_title: Osobennosti immuniteta u bolńykh keratokonusom.