[Differential combined drug therapy of phantom pain syndrome after amputation of extremity].
The authors consider that failures in the treatment of phantom pain syndrome (PPS) are explained by the lack of individual approach to the clinical manifestations of the syndrome. Three main clinical forms of PPS are distinguished using McGillow's questionnaire: causalgic, neuralgic, and spastic. Differentiated therapy for each form is proposed: combinations of amitriptyline, propranolol, and phenazepam for the first form, carbamazepine, propranolol, and phenazepam for the second, and tizanidine monotherapy for the third form. The efficacy of such therapy is approximately 75.2%, incidence of relapses during a year's follow up 12.4%.
Kukushkin
M L
ML
Laboratory of Pathophysiology, NII Common Pathology and Pathophysiology RAMN.
Ivanova
A F
AF
Ovechkin
A M
AM
Gnezdilov
A V
AV
Reshetniak
V K
VK
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000328:Adult; D000700:Analgesics / Q000627:therapeutic use*; D000927:Anticonvulsants / Q000627:therapeutic use*; D000928:Antidepressive Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy* / Q000209:etiology; D010591:Phantom Limb / Q000150:complications / Q000188:drug therapy*; D013577:Syndrome
D000319:Adrenergic beta-Antagonists; D000700:Analgesics; D000927:Anticonvulsants; D000928:Antidepressive Agents
Differentsialńaia kompleksnaia farmakoterapiia fantomno-bolevogo sindroma posle amputatsii konechnosti.