[Effect of long-chain polyunsaturated fatty acids on arachidonate and docosahexaeonic acid in healthy infants in the first four months of life].
Fatty acid compositions of plasma phospholipids (PL), triglycerides (TG) and sterol esters (STE) were measured by high resolution capillary gas-liquid chromatography in formula fed healthy infants at the ages of 5 days and 1, 2, 3 and 4 months. The infants were randomly assigned to receive either conventional infant formula (F, n = 10) without long-chain polyunsaturates (LCP) or the same formula supplemented with LCP (LCP-F, n = 12) in amounts and ratios similar to those characteristic to human milk. From the age of 1 month onwards, percentage contributions of the principal omega-6 LCP, arachidonic acid were significantly higher in plasma lipids of infants fed LCP-F than in those receiving conventional formula without dietary LCP. Values of the principal omega-3 LCP, docosahexaenoic acid were also significantly lower in the infants fed conventional formula than in those receiving LCP-F throughout the study. The data obtained indicate that from the formula supplemented with LCP both arachidonic and docosahexaenoic acids were effectively absorbed and incorporated into infantile plasma lipids. Recent data of the literature suggest that supplementation of infant formula with LCP may beneficially influence visual and psychomotor development also in healthy, term infants.
Decsi
T
T
Pécsi Orvostudományi Egyetem Gyermekgyógyászati Klinika.
Szász
M
M
Sárkány
I
I
Botykai
A
A
Berthold
K
K
D001095:Arachidonic Acids / Q000097:blood; D001724:Birth Weight; D001942:Breast Feeding; D004041:Dietary Fats / Q000097:blood; D005227:Fatty Acids / Q000097:blood; D005231:Fatty Acids, Unsaturated / Q000097:blood*; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn
D001095:Arachidonic Acids; D004041:Dietary Fats; D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; C007547:behenic acid
Hosszú szénláncú, többszörösen telítetlen zsírsavak hatása egészséges csecsemók arachidonsav-és dokozahexénsav-ellátottságára 92 eletelsonegy honapjaban.