title: [Gastric emptying as an etiopathogenic factor in gastroesophageal reflux disease].
abstract: The aim of this study is to evaluate gastric emptying change in patients with gastroesophageal reflux (GER). To this purpose, 36 patients with GER diagnosis and 18 control subjects have been studied. GER diagnosis was achieved by means of endoscopy, biopsy and 24 h continuous pH monitoring. Gastric emptying studies were performed on a two day basis, similar labelling meals were provided to patients and control subjects. Those consisted in a one-egg omelette, chicken (110 gr) and orange juice (200 ml). On first day liquid phase was labelled with 99mTc-diethylenetriamine pentaacetic acid (99mTc-DTPA), and on second day, the solid phase was labelled with 99mTc-sulfur colloid in the omelette (Labelling efficiency was 85.3 +/- 3.2%). The studies were carried out by imaging static anterior and posterior views every 20 minutes for a total of 180 minutes. Images were quantified obtaining solid and liquid gastric emptying curves. No statistical significative difference between patients and control subjects gastric emptying results were found. We can conclude that gastric emptying is not a main factor in the pathogenesis of gastroesophageal reflux.
authors.affiliation: Servicio de Digestivo, Hospital Reina Sofía, Córdoba.
authors.forename: M J
authors.initials: MJ
authors.lastname: Polonio García
authors.forename: J M
authors.initials: JM
authors.lastname: Llamas-Elvira
authors.forename: G
authors.initials: G
authors.lastname: Miño Fugarolas
authors.forename: G
authors.initials: G
authors.lastname: Costán
authors.forename: J L
authors.initials: JL
authors.lastname: Jaramillo
authors.forename: M
authors.initials: M
authors.lastname: Ureña Lara
authors.forename: M A
authors.initials: MA
authors.lastname: Muros de Fuentes
authors.forename: M D
authors.initials: MD
authors.lastname: Martínez del Valle
mesh_terms: D000328:Adult; D000368:Aged; D001628:Beverages; D001706:Biopsy; D004942:Esophagitis, Peptic / Q000209:etiology* / Q000503:physiopathology; D004945:Esophagoscopy; D004947:Esophagus / Q000473:pathology; D005260:Female; D005502:Food; D005745:Gastric Acidity Determination; D005746:Gastric Emptying; D005764:Gastroesophageal Reflux / Q000209:etiology* / Q000503:physiopathology; D005773:Gastroscopy; D006801:Humans; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index; D016284:Technetium Tc 99m Pentetate
chemical_list: D016284:Technetium Tc 99m Pentetate
vernacular_title: Estudio de la evacuación gástrica como factor etiopatogénico de la enfermedad por reflujo gastroesofágico.