Development of inhibitory mechanisms in the kitten's visual cortex.
The objective of this study was to evaluate the maturity of three inhibitory mechanisms (end-inhibition, side-inhibition, and cross-orientation inhibition) in the striate cortex of kittens at 4 weeks postnatal. To accomplish this, we made extracellular recordings from area 17 neurons while presenting visual stimuli consisting of sinusoidal luminance gratings or composites of gratings. We then compared data from kittens relating to various characteristics of each inhibitory mechanism with data from adults. We find that end-inhibition, side-inhibition, and cross-orientation inhibition are all present in kittens, and all show signs of maturity by 4 weeks postnatal. We conclude that the development of these inhibitory mechanisms occurs relatively early, and may coincide with the development of excitatory properties.
Green
E S
ES
Group in Neurobiology, School of Optometry, University of California, Berkeley, USA.
DeAngelis
G C
GC
Freeman
R D
RD
D000200:Action Potentials / Q000502:physiology; D000375:Aging / Q000502:physiology; D000818:Animals; D002415:Cats; D004594:Electrophysiology; D009474:Neurons / Q000502:physiology; D014793:Visual Cortex / Q000254:growth & development / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology