MURCS association: ultrasonographic findings and pathologic correlation.
MURCS association is a rare, lethal and unusual constellation of nonrandom findings that includes mullerian duct aplasia, renal aplasia, and cervicothoracic somite dysplasia.1-3 It has been described in 30 patients by Duncan and coworkers2 in 1979, in which report the authors proposed an embryologic cause for these defects.3 Antenatal ultrasonographic findings included a massive, cystic umbilical cord related to a patent urachus, enlarged bladder, single small kidney, and suspicion of urethral obstruction in a fetus of female phenotype. These findings are rare in a case of MURCS and were all confirmed on pathologic examination.
Fernandez
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Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Parkland Memorial Hospital, Dallas 75235, USA.
McFarland
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Timmons
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Ramus
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Twickler
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D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging* / Q000473:pathology; D000028:Abortion, Induced; D005260:Female; D005333:Fetus / Q000002:abnormalities*; D006801:Humans; D007668:Kidney / Q000002:abnormalities*; D009095:Mullerian Ducts / Q000002:abnormalities*; D011247:Pregnancy; D013131:Spine / Q000002:abnormalities*; D016216:Ultrasonography, Prenatal; D014564:Urogenital Abnormalities