title: Estimation of the percentage of carotid atheromatous plaque components and investigation of a probable correlation with the neurologic status of the patients.
abstract: The aim of this study was to estimate the percentage of the carotid atherosclerotic plaque components using image analysis in 50 cases of carotid endarterectomies as well as the search for a probable correlation with the neurologic status of the patients. According to their preoperational neurologic status, the patients were classified as asymptomatic (Group I), symptomatic-TIA (Group II) and symptomatic-previous stroke (Group III). For the image analysis and the exact estimation of the carotid plaque components, special algorithms were developed. The following plaque components were measured: fibrous component, calcium, cellular infiltrations, cholesterol and hemorrhage. Between the groups I-III, there was not found any statistically significant difference of the mean value of all the estimated parameters. Our results indicate that the morphology of the carotid atheromatous plaque seems not to be correlated with the neurologic status of the patients.
authors.affiliation: Department of Pathology, School of Medicine, National University of Athens, Greece.
authors.forename: E
authors.initials: E
authors.lastname: Agapitos
authors.forename: N
authors.initials: N
authors.lastname: Kavantzas
authors.forename: M
authors.initials: M
authors.lastname: Bakouris
authors.forename: P M
authors.initials: PM
authors.lastname: Pavlopoulos
authors.forename: K
authors.initials: K
authors.lastname: Kassis
authors.forename: C
authors.initials: C
authors.lastname: Liapis
authors.forename: M
authors.initials: M
authors.lastname: Sechas
authors.forename: P
authors.initials: P
authors.lastname: Davaris
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001161:Arteriosclerosis / Q000473:pathology*; D015415:Biomarkers / Q000032:analysis; D002339:Carotid Arteries / Q000737:chemistry* / Q000473:pathology*; D015140:Dementia, Vascular / Q000503:physiopathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008875:Middle Aged
chemical_list: D015415:Biomarkers