title: Posttransplant lymphoproliferative disease after cardiac transplantation. Two unusual variants with predominantly plasmacytoid features.
abstract: Two patients who developed posttransplant lymphoproliferative disorder with plasmacytoid changes in the lymphocytes after heart transplant are described. The first case is one of multiple myeloma, and the second is a case of lymphoma with plasmacytoid features. The clinical course and the etiologic role of the immunosuppressive therapies that the patients received for heart transplantation are described. A review of posttransplant multiple myeloma and discussion of the etiology and prognosis of this entity are presented.
authors.affiliation: Department of Hematology, Cleveland Clinic Foundation, Ohio 44195, USA.
authors.forename: T
authors.initials: T
authors.lastname: Fischer
authors.forename: M
authors.initials: M
authors.lastname: Miller
authors.forename: C
authors.initials: C
authors.lastname: Bott-Silverman
authors.forename: A
authors.initials: A
authors.lastname: Lichtin
mesh_terms: D016027:Heart Transplantation / Q000009:adverse effects*; D006801:Humans; D006965:Hyperplasia / Q000150:complications / Q000209:etiology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications / Q000209:etiology; D008232:Lymphoproliferative Disorders / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000209:etiology; D010950:Plasma Cells / Q000473:pathology; D015996:Survival Rate