title: Adenocarcinoma of the iris pigment epithelium.
abstract: We treated an 81-year-old man with a pigmented lesion of his right iris. The lesion was locally excised. Light microscopic examination, including immunohistochemistry, and electron microscopic examination were performed. The diagnosis was low-grade adenocarcinoma arising from the iris pigment epithelium. Adenomatous proliferations of the iris pigment epithelium are exceedingly rare and have not been shown to metastasize. Local resection is recommended if the lesion exhibits growth.
authors.affiliation: Department of Ophthalmology, Emory University School of Medicine, Atlanta, Ga, USA.
authors.forename: C W
authors.initials: CW
authors.lastname: Spraul
authors.forename: D
authors.initials: D
authors.lastname: d'Heurle
authors.forename: H E
authors.initials: HE
authors.lastname: Grossniklaus
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology* / Q000601:surgery; D000368:Aged; D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000032:analysis; D002387:Cataract Extraction; D006801:Humans; D015811:Iris Neoplasms / Q000473:pathology* / Q000601:surgery; D007910:Lenses, Intraocular; D008297:Male; D010857:Pigment Epithelium of Eye / Q000473:pathology* / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor