[Mutator genes from Saccharomyces cerevisiae. Interaction between HIM- and HSM-genes].
The interaction of six mutator genes of the yeast Saccharomyces cerevisiae with respect to UV-induced mutagenesis was studied. To this effect, double mutants with a genotype containing pairs of mutations at genes analyzed were synthesized. Analysis of the type of interaction of these mutations revealed four epistatic gene groups: (1) HIM1, HSM3, and HSM6; (2) HSM1; (3) HSM2; and (4) HIM2 and HIM3. The possible role of genes studied in different repair pathways of mispaired bases was discussed.
Koval'tsova
S V
SV
Gracheva
L M
LM
Evstiukhina
T A
TA
Fedorova
I V
IV
Korolev
V G
VG
D003470:Culture Media; D004260:DNA Repair; D005800:Genes, Fungal; D005838:Genotype; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000235:genetics*; D014466:Ultraviolet Rays
D003470:Culture Media
Geny-mutatory drozhzheĭ Saccharomyces cerevisiae. Vzaimodeĭstvie mezhdu HIM- i HSM-genami.