Linkage and cytogenetic mapping of a CAG repeat containing human cDNA to 3p24.2-p22.
A trinucleotide (CAG)n repeat containing cDNA was isolated from a human cDNA library and sequenced. The locus was mapped by linkage analysis in the CEPH families and by cytogenetic analysis to 3p24.2-p22. We have additionally excluded this gene as a candidate for small cell lung carcinoma by the analysis of cell lines carrying homozygous deletions for the 3p chromosomal region.
Polymeropoulos
M H
MH
National Center for Human Genome Research, Laboratory of Genetic Disease Research, National Institutes of Health, Bethesda, Maryland 20892, USA.
Ide
S E
SE
Becker
K
K
Naylor
S L
SL
D002874:Chromosome Mapping / Q000379:methods*; D002881:Chromosomes, Human, Pair 12 / Q000235:genetics; D002893:Chromosomes, Human, Pair 3 / Q000235:genetics*; D018076:DNA, Complementary / Q000235:genetics*; D006801:Humans; D017422:Sequence Analysis, DNA; D018911:Trinucleotide Repeats / Q000235:genetics*
D018076:DNA, Complementary