title: Clinical and pathological heterogeneity in cutaneous gamma-delta T-cell lymphoma: a report of three cases and a review of the literature.
abstract: Cutaneous gamma-delta (gamma delta) T-cell lymphoma is rare. Eleven cases have been reported to date including four cases of mycosis fungoides (MF), two of pagetoid reticulosis and five of pleomorphic cutaneous T-cell lymphoma (CTCL). We report three further cases of cutaneous gamma delta T-cell lymphoma; one of MF, one of a pleomorphic CTCL and one of a subcutaneous T-cell lymphoma. Combined data suggest that although cutaneous gamma delta T-cell lymphomas do not appear to comprise a single clinicopathological entity, they may be associated with aggressive clinical behaviour and a poor prognosis.
authors.affiliation: Department of Dermatology, Ealing Hospital, Middlesex, U.K.
authors.forename: S E
authors.initials: SE
authors.lastname: Munn
authors.forename: J M
authors.initials: JM
authors.lastname: McGregor
authors.forename: A
authors.initials: A
authors.lastname: Jones
authors.forename: P
authors.initials: P
authors.lastname: Amlot
authors.forename: M H
authors.initials: MH
authors.lastname: Rustin
authors.forename: R
authors.initials: R
authors.lastname: Russell Jones
authors.forename: S
authors.initials: S
authors.lastname: Whittaker
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D016410:Lymphoma, T-Cell, Cutaneous / Q000276:immunology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D016692:Receptors, Antigen, T-Cell, gamma-delta; D012867:Skin / Q000473:pathology*
chemical_list: D016692:Receptors, Antigen, T-Cell, gamma-delta