Neutrontherapy in soft tissue sarcomas: a review of European results.
The purpose of this publication is to review the data on European neutrontherapy facilities in the treatment of soft tissue sarcoma. Data on 1171 patients treated at 11 centers were analyzed. Neutrontherapy was of advantage especially for patients with primary radiotherapy of inoperable tumors, and those with macroscopic disease after surgery. Local control was about 50% in these groups. Results for postoperative neutrontherapy after R0 and R1 resection were similar to those for photon therapy. The incidence of late side effects was considerable. This was influenced by the fact that most patients were treated with first-generation machines.
Schwarz
R
R
Abteilung für Strahlentherapie, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
Krüll
A
A
Steingräber
M
M
Lessel
A
A
Engenhart
R
R
Favre
A
A
Breteau
N
N
Prott
F J
FJ
Auberger
T
T
Schmidt
R
R
D018572:Disease-Free Survival; D005060:Europe; D005214:Fast Neutrons; D006801:Humans; D008137:Longitudinal Studies; D009367:Neoplasm Staging; D017785:Photons; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy / Q000009:adverse effects / Q000379:methods; D012509:Sarcoma / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D012983:Soft Tissue Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*