[Bovine spongiform encephalopathy. Review of data collected since the statement of February 6, 1996].
The observation in 1995 and 1996 of 10 cases of a new variant of Creutzfeldt-Jakob disease (V-CJD) in U.K. suggested a possible relation between this human cases and bovine spongiform encephalopathy (BSE). Recent papers about this topic are reviewed : hypothesis of a possible genetic link between man and cattle, hypothesis of a acquired resistance against the agent of BSE after a previous infection by a less virulent agent of ovine origin, importance of polymorphism at codon 129 according to the hypothesis of a virus-induced amyloidosis, diagnostic test with cerebrospinal fluid, epidemiology of BSE and prediction of future BSE spread.
Brugère-Picoux
J
J
Pathologie mĕdicale du bétail et des animaux de basse-cour, Ecole nationale vétérinaire d'Alfort, Maisons-Alfort, France.
Rérat
A
A
D000818:Animals; D002417:Cattle; D007562:Creutzfeldt-Jakob Syndrome / Q000453:epidemiology / Q000235:genetics* / Q000821:virology; D016643:Encephalopathy, Bovine Spongiform / Q000453:epidemiology / Q000235:genetics* / Q000821:virology; D006801:Humans; D015994:Incidence; D011110:Polymorphism, Genetic
Encéphalopathie spongiforme bovine. Mise au point des données recueillies depuis le voeu du 6 février 1996.