title: [Ophthalmological exploration of children with Down's syndrome. Main results and comparison with a control group].
abstract: BACKGROUND
  Down's Syndrome is the most frequent chromosomal aberration. There is a wide variety of symptoms. From an ophthalmological point of view, numerous alterations associated with Down's Syndrome have been described.
  
  
  METHODS
  We have carried out a complete ophthalmic exploration on 60 children with Down's Syndrome and 60 control children.
  
  
  RESULTS
  The first group showed a high percentage of refraction errors (90%), nystagmus (28%), strabismus (48%) and cataracts (13%). If we compare these results with those of the control group we find that the Down's group has a frequency significantly higher both in refraction errors as a whole (p < 0.001) and myopia (p < 0.01), hypermetropia (p < 0.02) and stigmatism (p < 0.001). They have also shown a frequency significantly higher of strabismus (p < 0.001).
  
  
  CONCLUSIONS
  All of the observed alterations can have a negative influence on the appropriate educational development of these children. An early ophthalmological exploration would be advisable in children with Down's Syndrome.
authors.affiliation: Hospital Miguel Servet, Servicio de Oftalmología, Zaragoza.
authors.forename: I
authors.initials: I
authors.lastname: González Viejo
authors.forename: C
authors.initials: C
authors.lastname: Ferrer Novella
authors.forename: E
authors.initials: E
authors.lastname: Ferrer Novella
authors.forename: M
authors.initials: M
authors.lastname: Pueyo Subías
authors.forename: J
authors.initials: J
authors.lastname: Bueno Lozano
authors.forename: E
authors.initials: E
authors.lastname: Vicente Aznar
mesh_terms: D002386:Cataract / Q000150:complications* / Q000175:diagnosis*; D002648:Child; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D009759:Nystagmus, Pathologic / Q000150:complications* / Q000175:diagnosis*; D012030:Refractive Errors / Q000150:complications* / Q000175:diagnosis*; D013285:Strabismus / Q000150:complications* / Q000175:diagnosis*
vernacular_title: Exploración oftalmológica en niños con síndrome de Down: principales resultados y comparación con un grupo control.