title: Cytogenetic analysis in a case of intraocular medulloepithelioma.
abstract: We report the cytogenetic analysis of a medulloepithelioma, a rare neuroectodermally-derived tumor of childhood, which to our knowledge is the first reported karyotype of this tumor. The tumor sample was received at diagnosis and was mechanically dissociated to create cell suspension cultures. The primary cytogenetic abnormality was a der(16)t(1;16) chromosome, which was typical of that reported in a wide range of other tumor types. The other abnormalities seen were a del(6q) and monosomy 15.
authors.affiliation: Department of Oncology, Universitäts-Kinderklinik Zürich, Switzerland.
authors.forename: D R
authors.initials: DR
authors.lastname: Betts
authors.forename: K E
authors.initials: KE
authors.lastname: Leibundgut
authors.forename: F K
authors.initials: FK
authors.lastname: Niggli
mesh_terms: D002648:Child; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D025063:Chromosome Disorders; D002878:Chromosomes, Human, Pair 1; D002884:Chromosomes, Human, Pair 15; D002924:Ciliary Body; D015353:Eye Enucleation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007621:Karyotyping; D009006:Monosomy; D018302:Neoplasms, Neuroepithelial / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D014178:Translocation, Genetic; D014407:Tumor Cells, Cultured; D014604:Uveal Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery