Application of arylosulfonic acids in analysis of antihypertensive drugs.
Suitability of four arylosulfonic acids and their sodium salts to form derivatives with hypotensive drugs were studied. New crystalline arylosulfonates of todralazine, hydralazine and dihydralazine were obtained. Physico-chemical properties of the obtained arylosulfonates were tested. Reagents mentioned above were also used in analysis of these drugs.
Gajewska
M
M
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, School of Medicine, Warsaw, Poland.
Sokołowska-Muszyńska
M
M
Iliaszenko
J
J
Somogi
A
A
D000959:Antihypertensive Agents / Q000032:analysis*; D004078:Dihydralazine / Q000032:analysis*; D006830:Hydralazine / Q000032:analysis*; D013451:Sulfonic Acids / Q000032:analysis*; D014032:Todralazine / Q000032:analysis*
D000959:Antihypertensive Agents; D013451:Sulfonic Acids; D006830:Hydralazine; D004078:Dihydralazine; D014032:Todralazine