title: [Comparative study of 201Tl and 99mTc-MIBI in breast tumor].
abstract: A comparative study of 201Tl and 99mTc-MIBI was performed in 39 breast tumors. 201Tl scintigraphy was carried out in 24 breast tumors and 99mTc-MIBI scintigraphy in 15. The sensitivity of 201Tl for malignant tumors was 100% (22/22), but specificity was 0% (0/2). On 99mTc-MIBI scintigraphy, the sensitivity for the malignant tumors was 83.3% (10/12) and specificity was 100% (3/3). 99Tc-MIBI might be more useful for the diagnosis of breast tumors, because the tumor/background ratio of 99mTc-MIBI was significantly higher than that of 201Tl. In addition, 201Tl scintigraphy and 99mTc-MIBI scintigraphy showed the same degree of accuracy (93.3%) in diagnosis of lymph node reached. Moreover, when either US and 201Tl or 99mTc-MIBI scintigraphy was positive for lymph node metastasis, accuracy of detection of lymph node metastasis became 94.4%. A combined study of US and scintigraphy might improve the accuracy for diagnosis of lymph node metastasis.
authors.affiliation: Department of Radiology, Jikei University school of Medicine.
authors.forename: N
authors.initials: N
authors.lastname: Fukumitsu
authors.forename: M
authors.initials: M
authors.lastname: Tozaki
authors.forename: M
authors.initials: M
authors.lastname: Uchiyama
authors.forename: Y
authors.initials: Y
authors.lastname: Mori
authors.forename: K
authors.initials: K
authors.lastname: Kawakami
authors.forename: K
authors.initials: K
authors.lastname: Uchida
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging*; D008875:Middle Aged; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D013794:Thallium Radioisotopes; D017256:Technetium Tc 99m Sestamibi