[The spectrum of the anti-ischemic activity of immobilized cytochrome c].
The antihypoxic, anti-ischemic and antianginal activity of biotechnological cytochrome c which had been immobilized on a dialdehydedextran and polyethyleneglycol carriers was studied in various experimental animals (mice, rats, rabbits). The immobilized cytochrome c exhibits higher antihypoxic and anti-ischemic activity on different models compared to cytochrome c.
Sernov
L N
LN
Ziuzina
C V
CV
Rozonov
Iu B
IuB
Belova
L A
LA
Gatsura
V V
VV
D000208:Acute Disease; D000787:Angina Pectoris / Q000188:drug therapy; D000818:Animals; D002317:Cardiovascular Agents / Q000627:therapeutic use*; D003574:Cytochrome c Group / Q000627:therapeutic use*; D004353:Drug Evaluation, Preclinical; D000860:Hypoxia / Q000188:drug therapy; D008297:Male; D051379:Mice; D017202:Myocardial Ischemia / Q000188:drug therapy*; D011433:Propranolol / Q000627:therapeutic use; D011817:Rabbits; D051381:Rats
D002317:Cardiovascular Agents; D003574:Cytochrome c Group; D011433:Propranolol
Issledovanie spektra protivoishemicheskoĭ aktivnosti immobilizovannogo tsitokhroma c.