title: Synthesis and biological activities of some new 4,5-dihydro-1H-1,2,4-triazol-5-ones.
abstract: The reactions of 3-alkyl(aryl)-4-phenylamino-4,5-dihydro-1H-1,2,4-triazol-5-ones with appropriate alkyl halides via sodio derivatives were studied and the corresponding 1-alkyl-3-alkyl(aryl)-4-phenylamino-4,5-dihydro-1H-1,2,4-traizol-5 -ones were synthesized. Next, the new compounds were tested for their in vitro antimicrobial activities.
authors.affiliation: Department of Chemistry, Karadeniz Technical University, Trabzon, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Demirbas
authors.forename: C B
authors.initials: CB
authors.lastname: Johansson
authors.forename: N
authors.initials: N
authors.lastname: Duman
authors.forename: A A
authors.initials: AA
authors.lastname: Ikizler
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000959:Antihypertensive Agents / Q000138:chemical synthesis / Q000737:chemistry; D003049:Coccidiostats / Q000138:chemical synthesis / Q000737:chemistry; D003470:Culture Media; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D006540:Herbicides / Q000138:chemical synthesis / Q000737:chemistry; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects*; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D000959:Antihypertensive Agents; D003049:Coccidiostats; D003470:Culture Media; D006540:Herbicides