title: Multiple endocrine neoplasia type 1 associated with malignant lymphoma and other complications.
abstract: A 49-year-old female with multiple endocrine neoplasia (MEN) type 1 associated with malignant lymphoma, lipoma, functioning adenomatous goiter, non-functioning adrenal tumor, polyneuropathy, postoperative primary hyperparathyroidism, and hepatitis B virus was a human T lymphotropic virus type 1 (HTLV-1) carrier. She underwent parathyroidectomy for primary hyperparathyroidism at age 44. At age 49, examinations of the enlarged para-aortic lymph nodes revealed diffuse small non-cleaved B cell lymphoma in stage II, and other various complications were also found. Multiple tumorigenetic factors were considered to be involved in the present case.
authors.affiliation: Third Department of Internal Medicine, Miyazaki Medical College.
authors.forename: H
authors.initials: H
authors.lastname: Toshimori
authors.forename: M
authors.initials: M
authors.lastname: Okamoto
authors.forename: K
authors.initials: K
authors.lastname: Nakatsuru
authors.forename: H
authors.initials: H
authors.lastname: Hidaka
authors.forename: H
authors.initials: H
authors.lastname: Yamaguchi
authors.forename: Y
authors.initials: Y
authors.lastname: Ushiroda
authors.forename: A
authors.initials: A
authors.lastname: Kisanuki
authors.forename: H
authors.initials: H
authors.lastname: Tsubouchi
authors.forename: A
authors.initials: A
authors.lastname: Sumiyoshi
authors.forename: S
authors.initials: S
authors.lastname: Matsukura
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000150:complications; D005260:Female; D006042:Goiter / Q000150:complications; D015490:HTLV-I Infections / Q000150:complications; D006509:Hepatitis B / Q000150:complications; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications; D008067:Lipoma / Q000150:complications; D016393:Lymphoma, B-Cell / Q000150:complications; D008228:Lymphoma, Non-Hodgkin / Q000150:complications; D008875:Middle Aged; D018761:Multiple Endocrine Neoplasia Type 1 / Q000150:complications* / Q000235:genetics