title: Cutaneous lymphocytic vasculitis in acute myeloid leukaemia.
abstract: We report a 63-year-old woman who presented with an 8-week history of widespread indurated, purpuric lesions associated with weight loss of 7 kg and several episodes of epistaxis. A skin biopsy demonstrated a lymphocytic vasculitis with haemorrhage and parakeratosis. A blood film and bone marrow examination showed features of a myelodysplastic syndrome in transformation to acute myeloid leukaemia. Leucocytoclastic vasculitis and polyarteritis nodosa occur in association with acute myeloid leukaemia, but the association with lymphocytic vasculitis is new.
authors.affiliation: Department of Dermatology, Charing Cross and Westminster Medical School, London, U.K.
authors.forename: A M
authors.initials: AM
authors.lastname: Farrell
authors.forename: C
authors.initials: C
authors.lastname: Gooptu
authors.forename: D
authors.initials: D
authors.lastname: Woodrow
authors.forename: C
authors.initials: C
authors.lastname: Costello
authors.forename: C B
authors.initials: CB
authors.lastname: Bunker
authors.forename: J J
authors.initials: JJ
authors.lastname: Cream
mesh_terms: D000208:Acute Disease; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications*; D008875:Middle Aged; D010257:Paraneoplastic Syndromes / Q000209:etiology* / Q000473:pathology; D017445:Skin Diseases, Vascular / Q000209:etiology* / Q000473:pathology; D014657:Vasculitis / Q000209:etiology* / Q000473:pathology