title: Neurotransmitter and endocrine modulation of aggressive behavior and its components in normal humans.
abstract: Correlations between aggressiveness and its components and plasma concentrations of norepinephrine (NE), epinephrine (EPI), testosterone (T), cortisol (Cort) and prolactin (Prl) were studied in 158 physically and psychologically healthy male volunteers. Global aggressiveness, examined directly in the probands by the Buss-Durkee Hostility Inventory (BDHI), was not correlated with any of the biochemical parameters investigated, but reports by first-degree relatives and spouses showed positive correlations between global aggressiveness and NE and T levels. The BDHI scores for 'irritability' and 'resentment' were positively correlated with NE, T and Cort.
authors.affiliation: Centro Studi Farmacotossicodipendenze, S.E.R.T., Parma, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Gerra
authors.forename: P
authors.initials: P
authors.lastname: Avanzini
authors.forename: A
authors.initials: A
authors.lastname: Zaimovic
authors.forename: G
authors.initials: G
authors.lastname: Fertonani
authors.forename: R
authors.initials: R
authors.lastname: Caccavari
authors.forename: R
authors.initials: R
authors.lastname: Delsignore
authors.forename: F
authors.initials: F
authors.lastname: Gardini
authors.forename: E
authors.initials: E
authors.lastname: Talarico
authors.forename: R
authors.initials: R
authors.lastname: Lecchini
authors.forename: D
authors.initials: D
authors.lastname: Maestri
authors.forename: F
authors.initials: F
authors.lastname: Brambilla
mesh_terms: D000293:Adolescent; D000328:Adult; D000374:Aggression / Q000502:physiology*; D004644:Emotions / Q000502:physiology; D004837:Epinephrine / Q000097:blood; D006728:Hormones / Q000097:blood / Q000502:physiology*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D008875:Middle Aged; D018377:Neurotransmitter Agents / Q000097:blood / Q000502:physiology*; D009638:Norepinephrine / Q000097:blood; D010552:Personality Assessment; D011388:Prolactin / Q000097:blood; D012016:Reference Values; D013739:Testosterone / Q000097:blood
chemical_list: D006728:Hormones; D018377:Neurotransmitter Agents; D013739:Testosterone; D011388:Prolactin; D006854:Hydrocortisone; D009638:Norepinephrine; D004837:Epinephrine