Some physico-chemical properties micelle--benzalkonium chloride (BAC) adduct on interface in selected eye drops.
In selected eye drops the value of surface tension coefficient delta 25 and critical micelle concentration (cmc) was determined. Calculation of the hydrophilic-lipophilic balance level (HLBcmc) and the solution of the surface state f.Am = K.T form of Gibbs equation enables the estimation of the type of action of micelle with lipid corneal epithelium. Particular attention has been paid to the forms of eye drops which contain benzalkonium chloride (BAC).
Zawadzka
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E
Department of Applied Pharmacy, Medical University of Lodz, Poland.
Stefański
P
P
Zgoda
M M
MM
D000818:Animals; D001548:Benzalkonium Compounds / Q000737:chemistry*; D002482:Cellulose / Q000737:chemistry; D003315:Cornea / Q000378:metabolism; D004847:Epithelial Cells; D004848:Epithelium / Q000378:metabolism; D050356:Lipid Metabolism; D008823:Micelles; D009883:Ophthalmic Solutions / Q000592:standards*; D011142:Polyvinyl Alcohol / Q000737:chemistry; D013500:Surface Tension
D001548:Benzalkonium Compounds; D008823:Micelles; D009883:Ophthalmic Solutions; D011142:Polyvinyl Alcohol; D002482:Cellulose