title: Labels of surface-seeking radionuclides in the human skeleton.
abstract: A biokinetic model of the distribution and generation of skeletal labels of 239Pu in the human body is presented. The model is based on available information on the microdistribution of transuranics elements in animals and humans. It also makes use of morphometric and histomorphometric data characterizing the human skeleton and its turnover. The model correctly describes essential features of the microdistribution established from autoradiographic analyses. Calculated concentrations of skeletal labels of 239Pu are in good agreement with measurements from a human injection case.
authors.affiliation: Forschungszentrum Karlsruhe, Hauptabteilung Sicherheit/Strahlenschutz, Karlsruhe, Germany.
authors.forename: E
authors.initials: E
authors.lastname: Polig
mesh_terms: D000818:Animals; D016723:Bone Remodeling / Q000502:physiology; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000378:metabolism*; D006801:Humans; D008954:Models, Biological; D011005:Plutonium / Q000493:pharmacokinetics; D011868:Radioisotopes / Q000493:pharmacokinetics*; D011877:Radionuclide Imaging
chemical_list: D011868:Radioisotopes; D011005:Plutonium