title: [Severe pre-eclampsia in 3 generations. Case report on heritability of pre-eclampsia].
abstract: A case of pre-eclampsia/eclampsia appearing in three generations is presented combined with a review of literature. It is unknown whether the maternal genotype or the combination of the fetal and the maternal genotype is responsible for a disposition to this disease. Moreover the heredity as an autosomal-recessive or a dominant one with incomplete penetrance is in dispute. Further investigation will be convenient to improve the definition of groups at risk and a possible pharmacological prophylaxis.
authors.affiliation: Frauenklinik des Krankenhauses Bethanien Moers.
authors.forename: D
authors.initials: D
authors.lastname: Watermann
authors.forename: P
authors.initials: P
authors.lastname: Tönnies
mesh_terms: D000328:Adult; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011225:Pre-Eclampsia / Q000175:diagnosis / Q000235:genetics*; D011247:Pregnancy; D012307:Risk Factors
vernacular_title: Schwere Präeklampsie in drei Generationen. Falldarstellung zur Erblichkeit der Präeklampsie.