[IgM antibody against sulfated glucuronyl paragloboside in a case of Guillain-Barré syndrome].
High-titer IgM antibody against sulfated glucuronyl paragloboside (SGPG) was detected in a case of Guillain-Barré syndrome. The patient recovered rapidly by the treatment with double filtration plasmapheresis and the anti-SGPG antibody was not detected on the 40th day of illness. Facial nerve palsy, however, lasted until the 6th month of illness. Anti-SGPG antibody might have the important role in the pathologic mechanisms of Guillain-Barré syndrome in this case.
Yoshino
H
H
Department of Neurology, National institute of Neurology and Psychiatry, Kohnodai Hospital.
Shibata
S
S
Arita
M
M
D000328:Adult; D005915:Globosides / Q000276:immunology*; D006801:Humans; D007075:Immunoglobulin M / Q000032:analysis*; D008297:Male; D010956:Plasmapheresis; D011129:Polyradiculoneuropathy / Q000276:immunology* / Q000628:therapy
D005915:Globosides; D007075:Immunoglobulin M; C051917:sulfate-3-glucuronyl paragloboside