[The level of embryonic antigens in the blood serum and cerebrospinal fluid of neuro-oncological patients].
The levels of embryonic antigens (cancer embryonic antigen, alpha-fetoprotein, beta-chorionic gonadotropin were measured in the serum, spinal fluid, the cystic fluid of tumor 83 of neuro-oncological patients. It was found that the blood concentrations of cancer embryonic antigen and alpha-fetoprotein were not generally related to the degree of malignancy and the blood level of beta-chorionic gonadotropin decreased with the higher degree of tumor anaplasia. The high content of beta-chorionic gonadotropin in the spinal fluid suggests its origin from a brain tumor. The fatal postoperative outcome was noted in patients having high preoperative serum levels of alpha-fetoprotein and cancer embryonic antigen with simultaneous much higher concentrations of alpha-fetoprotein in the serum than those in the spinal fluid.
Rudenko
V A
VA
Lisianyĭ
N I
NI
Grinevich
Iu A
IuA
Burkatovskaia
M B
MB
Iugrinova
L G
LG
D000708:Anaplasia / Q000175:diagnosis / Q000601:surgery; D001254:Astrocytoma / Q000175:diagnosis* / Q000601:surgery; D014408:Biomarkers, Tumor / Q000032:analysis*; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000601:surgery; D002272:Carcinoembryonic Antigen / Q000032:analysis*; D006063:Chorionic Gonadotropin / Q000032:analysis*; D005909:Glioblastoma / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007124:Immunoenzyme Techniques / Q000706:statistics & numerical data; D007432:Intraoperative Period; D011184:Postoperative Period; D013997:Time Factors; D000509:alpha-Fetoproteins / Q000032:analysis*
D014408:Biomarkers, Tumor; D002272:Carcinoembryonic Antigen; D006063:Chorionic Gonadotropin; D000509:alpha-Fetoproteins
Soderzhanie émbrional'nykh antigenov v syvorotke krovi i likvore neĭroonkologicheskikh bol'nykh.