Differential expression of hepatic stearoyl-CoA desaturase gene 1 in male and female mice.
The expression of hepatic stearoyl-CoA desaturase (SCD1) mRNA abundance and the fatty acid profile in male and female mice were compared. The expression of the SCD1 mRNA is significantly higher in female compared to male mice and that this difference is accompanied by higher levels of palmitoleic and oleic acid in the livers of female mice.
Lee
K N
KN
Department of Nutritional Sciences, University of Wisconsin-Madison 53706, USA.
Pariza
M W
MW
Ntambi
J M
JM
D000818:Animals; D004032:Diet; D005227:Fatty Acids / Q000032:analysis*; D005229:Fatty Acids, Monounsaturated / Q000032:analysis; D005260:Female; D015870:Gene Expression; D008099:Liver / Q000737:chemistry / Q000201:enzymology*; D008297:Male; D051379:Mice; D008813:Mice, Inbred ICR; D019301:Oleic Acid / Q000032:analysis; D012333:RNA, Messenger / Q000032:analysis; D012727:Sex Characteristics; D013230:Stearoyl-CoA Desaturase / Q000096:biosynthesis*
D005227:Fatty Acids; D005229:Fatty Acids, Monounsaturated; D012333:RNA, Messenger; C008757:palmitoleic acid; D019301:Oleic Acid; D013230:Stearoyl-CoA Desaturase