title: [Ovarian hyperstimulation with menotropins as treatment for unexplained sterility; effect of reproductive characteristics on the results].
abstract: The objective was to evaluate the utility of the ovarian hyperstimulation with menotropins as treatment of unexplained infertility. One hundred couples with unexplained infertility were treated. Ovarian stimulation was started with 150 IU of menotropins on day 3 of the menstrual cycle, monitoring the follicular growth with transvaginal ultrasonography, additional doses of menotropins were administered accordingly. Human chorionic gonadotropin (10000 IU) was administered when the dominant follicle reached a diameter > or = 16 mm. The pregnancy rate per cycle was 12.0%, on the other hand the cumulate rate of pregnancy was 48.0%. The age under 30 years and the antecedent of previous pregnancies were correlated with the likelihood of conception. The spontaneous abortion rate was 35.4%. As conclusion, it therefore appears appropriate, to offer a treatment with menotropins to that specific group of couples with unexplained infertility with good prognostic factor as age < 30 years and infertility duration < 5 years. The increase on the spontaneous abortion rate was probably induced for the luteal insufficiency produced by the ovarian hyperstimulation with menotropins.
authors.affiliation: Unidad de Reproducción Asistida. Clínica de Infertilidad-Endoscopia y Embarazo de Alto riesgo, Hospital American British Cowdray (ABC). México, D.F.
authors.forename: A
authors.initials: A
authors.lastname: Kably
authors.forename: H
authors.initials: H
authors.lastname: Reyes-Cuervo
authors.forename: J
authors.initials: J
authors.lastname: Barrón-Vallejo
mesh_terms: D000022:Abortion, Spontaneous / Q000517:prevention & control; D000328:Adult; D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use*; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy*; D008596:Menotropins / Q000627:therapeutic use*; D010053:Ovary / Q000187:drug effects; D010062:Ovulation Induction / Q000379:methods*; D011247:Pregnancy; D011379:Prognosis
chemical_list: D005300:Fertility Agents, Female; D008596:Menotropins
vernacular_title: Hiperestimulación ovárica con menotropinas como tratamiento para la esterilidad inexplicable; efecto de las características reproductivas en los resultados obtenidos.