Predictive value of proliferative cellular nuclear antigen (PCNA) and Ki-67 antigen in advanced stage serous papilliferous ovarian cancer.
The cell nuclear antigens PCNA (Proliferative cell nuclear antigen) and Ki-67 in selected advanced serous papilliferous ovarian cancers were evaluated by histochemical assays. PCNA and Ki-67 expression in primitive tumor cells appeared to be correlated with grading, stage and survival. High expression was found in G3 and in more advanced stages while in low expression survival rate was better.
Altavilla
G
G
Gynecological Oncology Department, University of Padua, Italy.
Marchetti
M
M
Padovan
P
P
Marcato
E
E
Onnis
A
A
D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis*; D018283:Cystadenocarcinoma, Papillary / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D019394:Ki-67 Antigen / Q000032:analysis*; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology; D011379:Prognosis; D018809:Proliferating Cell Nuclear Antigen / Q000032:analysis*; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D015996:Survival Rate
D014408:Biomarkers, Tumor; D019394:Ki-67 Antigen; D018809:Proliferating Cell Nuclear Antigen