Polyclonal lymphoid tumor of the choroid plexus presenting as an intraventricular mass in a young gorilla.
An unusual lymphoid lesion with reactive germinal centers, occurring in the choroid plexus of a young gorilla, is reported. It presented as a large mass in the lateral ventricle with hydrocephalus and neurological symptoms. A work-up did not reveal any underlying cause for this lesion. No similar lesion of the choroid plexus has been reported in either human or veterinary literature. Histological work-up, including flow cytometry, gene rearrangement studies and T and B cell markers, favored the lesion being a non-neoplastic lymphoid proliferation of unknown etiology. The prognosis is unknown, although, following complete removal, the animal is well and free of tumor at the time of this report.
Thomas
C
C
Section of Neuropathology, Loyola University Medical Center, Maywood, IL 60153, USA.
Anderson
D
D
Grigg-Damberger
M
M
Gujrati
M
M
Lee
J M
JM
Murnane
R
R
Dizikes
G
G
Radvany
R
R
Walsh
T
T
Meehan
T P
TP
D000818:Animals; D018420:Ape Diseases / Q000175:diagnosis* / Q000473:pathology; D002551:Cerebral Ventricle Neoplasms / Q000662:veterinary*; D002648:Child; D016545:Choroid Plexus Neoplasms / Q000473:pathology / Q000662:veterinary*; D003937:Diagnosis, Differential; D006071:Gorilla gorilla; D006801:Humans; D008206:Lymphatic Diseases / Q000473:pathology / Q000662:veterinary*; D008297:Male