Possible prevention of postangioplasty restenosis by ascorbic acid.
In this preliminary study to assess the possibility of using ascorbic acid to prevent post-percutaneous transluminal coronary angiography (PTCA) restenosis, the incidence of restenosis was significantly less in 50 patients receiving 500 mg/day of oral ascorbic acid than in 51 control patients. Thus, ascorbic acid, a potent natural antioxidant, appeared to be possibly effective in attenuating post-PTCA restenosis.
Tomoda
H
H
Department of Cardiology, Tokai University, Kanagawa, Japan.
Yoshitake
M
M
Morimoto
K
K
Aoki
N
N
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015906:Angioplasty, Balloon, Coronary / Q000009:adverse effects*; D001205:Ascorbic Acid / Q000627:therapeutic use*; D002932:Cineangiography; D017023:Coronary Angiography; D003327:Coronary Disease / Q000209:etiology / Q000517:prevention & control*; D003936:Diagnosis, Computer-Assisted; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence
D001205:Ascorbic Acid