title: [Characteristics of anti-respiratory syncytial humoral immunity during persistence of respiratory syncytial virus antigens in adult patients with chronic obstructive bronchitis].
abstract: Specific humoral immune response has been studied in 8 patients with chronic obstructive bronchitis, in whom the persistence of RSV was detected, and in a group of patients without RSV persistence. Humoral immunity in patients with RSV persistence vs. those with acute and chronic bronchitis without viral persistence was characterized by the following features: a) earlier and more active production of IgG and, even more so, IgM and IgA; b) long persistence of high titers of anti-RSV IgG, IgM, and IgA-up to 17, 28, and 30 weeks, respectively; c) low anti-RSV neutralizing activity of serum antibodies.
authors.forename: V Z
authors.initials: VZ
authors.lastname: Krivitskaia
authors.forename: N V
authors.initials: NV
authors.lastname: Iakovleva
authors.forename: N I
authors.initials: NI
authors.lastname: Aleksandrova
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D000917:Antibody Formation; D001991:Bronchitis / Q000276:immunology / Q000821:virology*; D001992:Bronchoalveolar Lavage Fluid / Q000276:immunology / Q000821:virology; D002908:Chronic Disease; D006801:Humans; D018357:Respiratory Syncytial Virus Infections / Q000276:immunology / Q000821:virology*; D018113:Respiratory Syncytial Virus, Human / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral
vernacular_title: Osobennosti anti-respiratorno-sintsitial'nogo gumoral'nogo immuniteta pri persistentsii antigenov respiratorno-sintsitial'nogo virusa u vzroslykh bol'nykh khronicheskim obstruktivnym bronkhitom.