An in vitro model of aneurysmal disease: effect of leukocyte infiltration and shear stress on MMP production within the arterial wall.
Thompson
M M
MM
Department of Surgery, University of Leicester, United Kingdom.
Wills
A
A
McDermott
E
E
Crowther
M
M
Brindle
N
N
Bell
P R
PR
D000818:Animals; D001013:Aorta, Thoracic / Q000187:drug effects / Q000201:enzymology* / Q000473:pathology; D001014:Aortic Aneurysm / Q000201:enzymology*; D002634:Chemotaxis, Leukocyte; D017364:Collagenases / Q000096:biosynthesis*; D004549:Elastin / Q000378:metabolism*; D004790:Enzyme Induction; D005109:Extracellular Matrix / Q000187:drug effects; D018093:Gelatinases / Q000096:biosynthesis*; D007962:Leukocytes / Q000201:enzymology*; D020778:Matrix Metalloproteinase 2; D020780:Matrix Metalloproteinase 9; D008666:Metalloendopeptidases / Q000096:biosynthesis*; D009924:Organ Culture Techniques; D010196:Pancreatic Elastase / Q000494:pharmacology; D013314:Stress, Mechanical; D013552:Swine
D004549:Elastin; D010196:Pancreatic Elastase; D017364:Collagenases; D018093:Gelatinases; D008666:Metalloendopeptidases; D020778:Matrix Metalloproteinase 2; D020780:Matrix Metalloproteinase 9