Suppression of experimental aneurysmal degeneration with chemically modified tetracycline derivatives.
Petrinec
D
D
Department of Surgery, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Holmes
D R
DR
Liao
S
S
Golub
L M
LM
Thompson
R W
RW
D000818:Animals; D017544:Aortic Aneurysm, Abdominal / Q000139:chemically induced / Q000188:drug therapy* / Q000201:enzymology; D002317:Cardiovascular Agents / Q000494:pharmacology / Q000627:therapeutic use*; D018450:Disease Progression; D004318:Doxycycline / Q000494:pharmacology / Q000627:therapeutic use; D004791:Enzyme Inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D008666:Metalloendopeptidases / Q000037:antagonists & inhibitors*; D010196:Pancreatic Elastase / Q000633:toxicity; D051381:Rats; D017208:Rats, Wistar; D013754:Tetracyclines / Q000494:pharmacology / Q000627:therapeutic use*
D002317:Cardiovascular Agents; D004791:Enzyme Inhibitors; D013754:Tetracyclines; D010196:Pancreatic Elastase; D008666:Metalloendopeptidases; D004318:Doxycycline