title: Lissencephaly with extreme cerebral and cerebellar hypoplasia. A magnetic resonance imaging study.
abstract: A newborn with a rare type of lissencephaly is reported, characterized by extreme cerebral and cerebellar hypoplasia. The diagnosis was made by postmortem magnetic resonance imaging, indicating the value of such studies to evaluate neuronal migration disorders in patients in whom autopsy cannot be performed. Two earlier described microlissencephaly syndromes, the "Barth" and "McComb" type, are reviewed.
authors.affiliation: Department of Neonatology, Academic Medical Centre, Amsterdam, The Netherlands.
authors.forename: A A
authors.initials: AA
authors.lastname: Kroon
authors.forename: B J
authors.initials: BJ
authors.lastname: Smit
authors.forename: P G
authors.initials: PG
authors.lastname: Barth
authors.forename: R C
authors.initials: RC
authors.lastname: Hennekam
mesh_terms: D002531:Cerebellum / Q000002:abnormalities* / Q000473:pathology; D002540:Cerebral Cortex / Q000002:abnormalities* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008831:Microcephaly / Q000473:pathology