title: Haemodynamic effects of descending aortic occlusion during cardiopulmonary resuscitation.
abstract: We describe two patients who both suffered a cardiac arrest whilst maintained on an intra-aortic balloon pump. In an attempt to improve coronary and cerebral blood flow during cardiopulmonary resuscitation, the intra-aortic balloon was inflated to occlude the descending aorta and preferentially direct blood to the cerebral and coronary circulation. In case 1, mean radial artery pressure rose from 71/14 mmHg (mean = 33 mmHg) to 92/24 mmHg (mean = 47 mmHg). Diastolic right atrial pressure was 16 mmHg both with the balloon deflated and inflated. In patient 2, mean radial artery pressure rose from 48/21 mmHg (mean = 25 mmHg) to 62/26 mmHg (mean = 36 mmHg). Right atrial pressure was 90/6 mmHg (mean 34 mmHg) with the balloon deflated and 104/8 mmHg (mean = 40 mmHg) with the balloon inflated. Coronary artery perfusion pressure in case 1 increased from -2 to 8 mmHg and in case 2 increased from 15 to 18 mmHg. These results suggest that occlusion of the descending aorta during cardiac massage may improve coronary and cerebral perfusion pressures. Animal studies are consistent with these findings and show that aortic occlusion may significantly improve outcome from cardiac arrest.
authors.affiliation: Department of Anaesthetics, Southampton General Hospital, UK.
authors.forename: C D
authors.initials: CD
authors.lastname: Deakin
authors.forename: D J
authors.initials: DJ
authors.lastname: Barron
mesh_terms: D001013:Aorta, Thoracic; D016887:Cardiopulmonary Resuscitation; D005260:Female; D006323:Heart Arrest / Q000503:physiopathology* / Q000628:therapy*; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D007423:Intra-Aortic Balloon Pumping; D008297:Male; D008875:Middle Aged