title: Presence of norepinephrine and other biogenic amines in stonefish venom.
abstract: Although fish venoms exert a cardiovascular effect, the presence of adrenergic substances was not previously demonstrated. Chromatographic analysis with electrochemical detection showed the presence of substances co-migrating with norepinephrine, dopamine and tryptophan. Serotonin, which was thought to be implicated in the intense pain following fish envenomation, was not detected. Norepinephrine was identified as a component of the stonefish Synanceia verrucosa venom by gas chromatography-mass spectrometry.
authors.affiliation: Laboratoire de Biologie et Contrôle des Organismes Parasites, Université de Paris-Sud, Châtenay-Malabry, France.
authors.forename: P
authors.initials: P
authors.lastname: Garnier
authors.forename: J M
authors.initials: JM
authors.lastname: Grosclaude
authors.forename: F
authors.initials: F
authors.lastname: Goudey-Perrière
authors.forename: V
authors.initials: V
authors.lastname: Gervat
authors.forename: P
authors.initials: P
authors.lastname: Gayral
authors.forename: C
authors.initials: C
authors.lastname: Jacquot
authors.forename: C
authors.initials: C
authors.lastname: Perrière
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000032:analysis* / Q000737:chemistry; D000818:Animals; D001679:Biogenic Amines / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004298:Dopamine / Q000032:analysis; D004563:Electrochemistry; D005397:Fish Venoms / Q000737:chemistry*; D005400:Fishes, Poisonous; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D009638:Norepinephrine / Q000032:analysis* / Q000737:chemistry; D014364:Tryptophan / Q000032:analysis
chemical_list: D000316:Adrenergic alpha-Agonists; D001679:Biogenic Amines; D005397:Fish Venoms; D014364:Tryptophan; D004298:Dopamine; D009638:Norepinephrine