title: Anaphylaxis induced by lentils.
abstract: BACKGROUND
  The legume food family is large and includes peanut and soybean, two of the most frequent causes of food allergy. Literature on type I hypersensitivity to lentils, also a legume, is scarce.
  
  
  OBJECTIVE
  To describe a child with repeated anaphylactic reactions related to lentils.
  
  
  METHODS
  Skin prick tests with both commercial and cooked extracts and serum-specific IgE measured by CAP-RIA were used to identify specific IgE antibodies to various legumes.
  
  
  RESULTS
  An 8-year-old girl suffered four episodes of anaphylaxis related to lentils from ages 3 to 7 years. The first three involved ingestion of cooked lentils and each time smaller amounts induced symptoms. The fourth episode occurred with inhalation exposure to cooking lentil soup. Subsequently, she presented with contact urticaria from raw chickpeas and an anaphylactic reaction after ingestion of cooked chickpeas. Prick tests showed strongly positive reactions to lentil and chickpea and weaker positive reactions to peanut, pea, soybean, and white bean. CAP-RIA was class 6 to lentil; class 5 to peanut, pea, and soybean; class 4 to white bean, and class 0 to green bean.
  
  
  CONCLUSIONS
  Severe type I hypersensitivity to lentils occurred in this patient and was associated with clinically relevant hypersensitivity to chickpeas. Prick tests and CAP-RIA demonstrated multiple positive reactions to other legumes.
authors.affiliation: Department of Dermatology, University of Athens A Sygros Hospital, Greece.
authors.forename: D
authors.initials: D
authors.lastname: Kalogeromitros
authors.forename: M
authors.initials: M
authors.lastname: Armenaka
authors.forename: I
authors.initials: I
authors.lastname: Galatas
authors.forename: O
authors.initials: O
authors.lastname: Capellou
authors.forename: A
authors.initials: A
authors.lastname: Katsarou
mesh_terms: D000707:Anaphylaxis / Q000209:etiology*; D000918:Antibody Specificity; D002648:Child; D007887:Fabaceae / Q000009:adverse effects*; D005260:Female; D005512:Food Hypersensitivity / Q000209:etiology*; D006801:Humans; D006968:Hypersensitivity, Delayed / Q000209:etiology; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D010946:Plants, Medicinal; D011863:Radioimmunoassay; D012882:Skin Tests
chemical_list: D007073:Immunoglobulin E