title: Congenital cystic adenomatoid malformation of the lung: CT-pathologic correlation.
abstract: OBJECTIVE
  The purpose of this study was to correlate CT findings of congenital cystic adenomatoid malformation (CCAM) of the lung with pathologic findings.
  
  
  METHODS
  CT scans of CCAM from 21 consecutive patients were analyzed retrospectively by two chest radiologists who achieved consensus. Pathologic findings were assessed by an experienced pulmonary pathologist. Preoperative CT findings were correlated with pathologic findings.
  
  
  RESULTS
  Areas with small cysts (< 2 cm in diameter) were seen on CT scans in 19 (90%) of 21 patients, whereas areas with a large cyst (> 2 cm in diameter) were observed in 18 patients (86%). Areas of consolidation (n = 9; 43%) with heterogeneous attenuation on enhanced scans and areas of low attenuation (lower than normal lung) around cystic lesions (n = 6; 29%) were also seen on CT scans. The diameter of the largest cyst seen on CT scans in each patient ranged from 1.0 to 8.0 cm (median, 4.5 cm). Cysts that CT showed to be filled with air, fluid, or both correlated completely with the pathologic findings. Areas of consolidation corresponded histologically to areas of glandular or bronchiolar structures with or without areas of endogenous lipoid or organizing pneumonia or mucus plugs. Areas of low attenuation corresponded to areas of microcysts blended with normal lung parenchyma.
  
  
  CONCLUSIONS
  CT scans show the variable internal characteristics of CCAM and can suggest the underlying pathology of such lesions.
authors.affiliation: Department of Radiology, Seoul National University, College of Medicine, South Korea.
authors.forename: W S
authors.initials: WS
authors.lastname: Kim
authors.forename: K S
authors.initials: KS
authors.lastname: Lee
authors.forename: I O
authors.initials: IO
authors.lastname: Kim
authors.forename: Y L
authors.initials: YL
authors.lastname: Suh
authors.forename: J G
authors.initials: JG
authors.lastname: Im
authors.forename: K M
authors.initials: KM
authors.lastname: Yeon
authors.forename: J G
authors.initials: JG
authors.lastname: Chi
authors.forename: B K
authors.initials: BK
authors.lastname: Han
authors.forename: M C
authors.initials: MC
authors.lastname: Han
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D008168:Lung / Q000000981:diagnostic imaging* / Q000473:pathology*; D008297:Male; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed