title: Short communication: the value of embolization therapy in painful osseous metastases from hepatocellular carcinomas; comparative study with radiation therapy.
abstract: We evaluated the therapeutic effect of transcatheter arterial embolization therapy (TAE) for painful osseous metastases from hepatocellular carcinoma (HCC) in comparison with radiation therapy (RT). TAE using gelatin sponge particles was performed for seven lesions in seven patients. Selective catheterization and embolization were successfully performed in all lesions. Within 10 days after TAE, complete pain relief (CR), partial relief (PR) and no relief (NR) were attained in 57%, 29% and 14%, respectively. RT was used to treat 34 lesions in 22 patients. The dose fractionation schedules were in the range 28.0-50.4 Gy, with 1.8-4.0 Gy per fraction. CR, PR and NR were attained in 47%, 47% and 6%, respectively. There were no serious complications related to these treatments. Both TAE and RT are effective and the treatment of choice should be selected on an individual basis.
authors.affiliation: Department of Radiology, Kumamoto University School of Medicine, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Murakami
authors.forename: Y
authors.initials: Y
authors.lastname: Baba
authors.forename: M
authors.initials: M
authors.lastname: Furusawa
authors.forename: T
authors.initials: T
authors.lastname: Yokoyama
authors.forename: R
authors.initials: R
authors.lastname: Nishimura
authors.forename: H
authors.initials: H
authors.lastname: Uozumi
authors.forename: Y
authors.initials: Y
authors.lastname: Hatanaka
authors.forename: Y
authors.initials: Y
authors.lastname: Yamashita
authors.forename: M
authors.initials: M
authors.lastname: Takahashi
mesh_terms: D001859:Bone Neoplasms / Q000532:radiotherapy / Q000556:secondary* / Q000628:therapy; D006528:Carcinoma, Hepatocellular / Q000532:radiotherapy / Q000556:secondary* / Q000628:therapy; D004621:Embolization, Therapeutic; D005069:Evaluation Studies as Topic; D005260:Female; D005781:Gelatin Sponge, Absorbable / Q000627:therapeutic use; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D010166:Palliative Care / Q000379:methods*; D012189:Retrospective Studies