title: Signal transduction by interleukin-12 and interleukin-2. A comparison and contrast.
authors.affiliation: Lymphocyte Cell Biology Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.
authors.forename: C M
authors.initials: CM
authors.lastname: Bacon
authors.forename: S S
authors.initials: SS
authors.lastname: Cho
authors.forename: J J
authors.initials: JJ
authors.lastname: O'Shea
mesh_terms: D000595:Amino Acid Sequence; D017871:Calcium-Calmodulin-Dependent Protein Kinases / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000502:physiology; D055504:Insulin Receptor Substrate Proteins; D018664:Interleukin-12 / Q000737:chemistry / Q000502:physiology*; D007376:Interleukin-2 / Q000737:chemistry / Q000502:physiology*; D053613:Janus Kinase 1; D053614:Janus Kinase 2; D053616:Janus Kinase 3; D008024:Ligands; D019869:Phosphatidylinositol 3-Kinases; D010750:Phosphoproteins / Q000378:metabolism; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000502:physiology; D019000:Phosphotyrosine / Q000378:metabolism; D011505:Protein-Tyrosine Kinases / Q000378:metabolism / Q000502:physiology; D011518:Proto-Oncogene Proteins; D011940:Receptor Aggregation; D018121:Receptors, Cytokine / Q000502:physiology; D018123:Receptors, Interleukin / Q000502:physiology; D053707:Receptors, Interleukin-12; D015375:Receptors, Interleukin-2 / Q000502:physiology; D050794:STAT1 Transcription Factor; D050796:STAT3 Transcription Factor; D050797:STAT4 Transcription Factor; D017386:Sequence Homology, Amino Acid; D015398:Signal Transduction; D015534:Trans-Activators / Q000502:physiology; D014157:Transcription Factors / Q000502:physiology
chemical_list: D004268:DNA-Binding Proteins; D055504:Insulin Receptor Substrate Proteins; D007376:Interleukin-2; D008024:Ligands; D010750:Phosphoproteins; D011518:Proto-Oncogene Proteins; D018121:Receptors, Cytokine; D018123:Receptors, Interleukin; D053707:Receptors, Interleukin-12; D015375:Receptors, Interleukin-2; D050794:STAT1 Transcription Factor; D050796:STAT3 Transcription Factor; D050797:STAT4 Transcription Factor; D015534:Trans-Activators; D014157:Transcription Factors; D018664:Interleukin-12; D019000:Phosphotyrosine; D019869:Phosphatidylinositol 3-Kinases; D017853:Phosphotransferases (Alcohol Group Acceptor); D011505:Protein-Tyrosine Kinases; D053613:Janus Kinase 1; D053614:Janus Kinase 2; D053616:Janus Kinase 3; D017871:Calcium-Calmodulin-Dependent Protein Kinases