title: [Prevalence of serologic markers of hepatitis B and D viruses in children of the Caiabi and Txucarramãe tribes from the Indian Reservation of Xingu, central Brazil].
abstract: The medical literature has shown that the inhabitants of the Amazon region are highly affected by hepatitis B and delta viruses infection, but this has never been studied in Indian children by age group. A study of the prevalence of serological markers of hepatitis B and delta viruses in Indian children aged 0 to 14 years living in the PIX was carried out. This Park is located in Central Brazil, a region which is in the transition between the savannab to the south and the Amazon jungle to the north. To determine the prevalence of HBV and HDV markers in Indian children and to characterize the route of HBV transmission in this region. Out of the 17 tribes living in the PIX, two--the Caiabi and the Txucarramãe--were chosen because both live in the North part of the Park, but have quite different ways of life. The overall prevalence of HBV serum markers was: HBsAg, 4.5%; anti-HBs, 39.6%; anti-HBc, 44.1%; any marker of HBV, 47.3%; and anti-HDV, 0.0%. However, a striking difference in the prevalence of hepatitis B markers was observed between the two tribes: younger Caiabi children were much less affected than the Txucarramãe ones. The prevalence of HBsAg in fertile women was 12%, being anti-HBe positive. Our data suggest that HBV infection is highly prevalent among Indian children living in this Indigenous Park and vertical infection is not an important route of transmission in either tribes.
authors.affiliation: Departamento de Pediatria, Escola Paulista de Medicina/Universidade Federal de São Paulo.
authors.forename: R A
authors.initials: RA
authors.lastname: Azevedo
authors.forename: A E
authors.initials: AE
authors.lastname: Silva
authors.forename: M L
authors.initials: ML
authors.lastname: Ferraz
authors.forename: L F
authors.initials: LF
authors.lastname: Marcopito
authors.forename: R G
authors.initials: RG
authors.lastname: Baruzzi
mesh_terms: D000293:Adolescent; D017677:Age Distribution; D015415:Biomarkers / Q000097:blood; D001938:Brazil / Q000453:epidemiology / Q000208:ethnology; D002648:Child; D002675:Child, Preschool; D005260:Female; D018963:Hepatitis Antigens / Q000097:blood*; D006509:Hepatitis B / Q000453:epidemiology* / Q000276:immunology; D006514:Hepatitis B Surface Antigens / Q000097:blood*; D006513:Hepatitis B e Antigens / Q000097:blood*; D003699:Hepatitis D / Q000453:epidemiology* / Q000276:immunology; D035923:Hepatitis delta Antigens; D006801:Humans; D007199:Indians, South American; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D019371:Topography, Medical
chemical_list: D015415:Biomarkers; D018963:Hepatitis Antigens; D006514:Hepatitis B Surface Antigens; D006513:Hepatitis B e Antigens; D035923:Hepatitis delta Antigens
vernacular_title: Prevalência dos marcadores sorológicos dos vírus da hepatite B e D em crianças das tribos Caiabi e Txucarramãe do Parque Indígena do Xingu, Brasil central.