title: An analysis of DTP-associated reactions by manufacturer, batch, vaccinator, series number and infant weight.
abstract: OBJECTIVE
  To determine whether two commonly used DTP batches manufactured by Rhöne-Poulenc Rorer were more reactogenic than two commonly used batches manufactured by the South African Institute of Medical Research.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  Six community clinics.
  
  
  METHODS
  Infants routinely scheduled for their first three DTP immunisations.
  
  
  METHODS
  Local and systemic adverse reactions following immunisation with DTP.
  
  
  RESULTS
  Local reactions were significantly more common with both Rhöne-Poulenc Rorer products.
  
  
  CONCLUSIONS
  All adverse reaction rates compared favourably with those reported by the Centers for Disease Control.
authors.affiliation: Department of Community Health, University of Stellenbosch, Tygerberg, W. Cape.
authors.forename: J G
authors.initials: JG
authors.lastname: Benadé
mesh_terms: D001835:Body Weight; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000008:administration & dosage / Q000009:adverse effects; D004305:Dose-Response Relationship, Drug; D004345:Drug Industry; D004348:Drug Labeling; D006801:Humans; D007223:Infant; D007273:Injections, Intramuscular; D011446:Prospective Studies; D013019:South Africa; D014611:Vaccination / Q000379:methods; D017778:Vaccines, Combined / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D015721:Diphtheria-Tetanus-Pertussis Vaccine; D017778:Vaccines, Combined