title: [Rhabdomyolysis induced by succinylcholine chloride and sevoflurane in an elderly man].
abstract: An 81-year-old man was scheduled for cervical lymph node biopsy. His laboratory data were within normal ranges. After induction of anesthesia with thiopental 175 mg and succinylcholine chloride (SCC) 40 mg, moderate masseter spasm was observed. Anesthesia was maintained with nitrous oxide, oxygen and sevoflurane. After the operation he had severe muscle pain and CK was elevated up to 81,400IU.l-1. The body temperature was not elevated above 37.2 degrees C during and after the operation. The skinned fiber examination, performed one month later, showed his calcium-induced-calcium-release (CICR) to be within normal ranges. We diagnosed him as rhabdomyolysis induced by coadministration of SCC and sevoflurane, especially SCC. We concluded that even in an elderly man, SCC should be administered cautiously.
authors.affiliation: Department of Anesthesiology, National Defense Medical College, Tokorozawa.
authors.forename: F
authors.initials: F
authors.lastname: Takamatsu
authors.forename: M
authors.initials: M
authors.lastname: Taoda
authors.forename: Y
authors.initials: Y
authors.lastname: Uchihashi
authors.forename: T
authors.initials: T
authors.lastname: Satoh
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000768:Anesthesia, General; D018685:Anesthetics, Inhalation / Q000009:adverse effects*; D001706:Biopsy; D004987:Ethers / Q000009:adverse effects*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008738:Methyl Ethers; D009467:Neuromuscular Depolarizing Agents / Q000009:adverse effects*; D012206:Rhabdomyolysis / Q000139:chemically induced*; D000077149:Sevoflurane; D013390:Succinylcholine / Q000009:adverse effects*
chemical_list: D018685:Anesthetics, Inhalation; D004987:Ethers; D008738:Methyl Ethers; D009467:Neuromuscular Depolarizing Agents; D000077149:Sevoflurane; D013390:Succinylcholine