title: [Benign lymphoproliferative lesions of the parotid gland in HIV infection].
abstract: The authors investigated the role of ultrasonography (US) as the method of choice in diagnosing parotid lesions in HIV+ patients. Bilateral parotid gland enlargement associated with laterocervical lymph node enlargement is a sign of HIV infection. This pathologic condition is observed in 2-10% of seropositive patients. Histology demonstrates benign lymphoproliferative lesions referrable to immune system activation. Our series consisted of 37 HIV+ patients monitored with US for a year, all patients had cytologic confirmation of their disease, with needle biopsy in 9 patients and with MR studies in 4 patients. US showed focal solid lesions, with cystic and mixed appearance in the 26 adult subjects and gross parenchymal inhomogeneity in the 11 children; laterocervical lymph node enlargement was associated in 31 cases. In the only two cases with unilateral parotid involvement, an abscess and a lymphoma were diagnosed. To conclude, US findings in HIV+ patients, although aspecific, can help make the correct diagnosis, if they are integrated with the patient's history and clinical findings.
authors.affiliation: Servizio di Radiologia, Azienda Ospedaliera Lazzaro Spallanzani, Roma.
authors.forename: L
authors.initials: L
authors.lastname: Cecconi
authors.forename: E
authors.initials: E
authors.lastname: Busi Rizzi
authors.forename: V
authors.initials: V
authors.lastname: Schininà
authors.forename: G
authors.initials: G
authors.lastname: Mazzuoli
mesh_terms: D000328:Adult; D005260:Female; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010305:Parotid Diseases / Q000150:complications* / Q000175:diagnosis
vernacular_title: Lesioni linfoproliferative benigne della parotide nelle infezioni da HIV.