[Treatment with hydroxyurea of polycythemia vera in a 11 year-old child].
BACKGROUND
Polycythemia vera is a very rare disease in childhood; its treatment for this reason is not well established.


METHODS
An 11-year-old boy was admitted for polycythemia vera. The three classical major criteria for this condition were present and no cause for secondary polyglobulia could be recognized. The patient was given hydroxyurea. Three years later, he is well with hematocrit below 50%.


CONCLUSIONS
Oral continuous myelosuppressive therapy with hydroxyurea may be proposed in children if there is no HLA-matched family member. Long-term follow-up is nevertheless necessary in order to detect relapse or side-effects of the treatment.
Vodoff
M V
MV
Service de pédiatrie, gastroentérologie et génétique médicale, CHRU de Lille, France.
Nelken
B
B
Vic
P
P
Farriaux
J P
JP
D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002648:Child; D006400:Hematocrit; D006801:Humans; D006918:Hydroxyurea / Q000627:therapeutic use*; D008297:Male; D011087:Polycythemia Vera / Q000097:blood / Q000188:drug therapy*
D000970:Antineoplastic Agents; D006918:Hydroxyurea
Traitement par hydroxyurée d'une polyglobulie primitive chez un enfant de 11 ans.