title: Identification of flecainide and lorcainide in blood by means of TLC.
abstract: New antiarrhythmics-flecainide and lorcainide-extracted from plasma were separated by TLC method on silica gel by ascending development, using suitable mobile phases. The substances were identified by reaction with indicators: Dragendorff reagent for lorcainide (up to the amount 50 ng) and acidified 15% FeCl3, followed by 15% KI and water for flecainide (up to the amount 500 ng).
authors.affiliation: Department of Medicinal Chemistry, Faculty of Pharmacy, School of Medicine, Lublin, Poland.
authors.forename: B
authors.initials: B
authors.lastname: Paw
authors.forename: L
authors.initials: L
authors.lastname: Przyborowski
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000032:analysis*; D044482:Benzeneacetamides; D002855:Chromatography, Thin Layer; D005424:Flecainide / Q000097:blood*; D006801:Humans; D010880:Piperidines / Q000097:blood*
chemical_list: D000889:Anti-Arrhythmia Agents; D044482:Benzeneacetamides; D010880:Piperidines; D005424:Flecainide; C015970:lorcainide