[The effect of GABA and piracetam on the qualitative and quantitative composition of the brain phospholipids in rats under hypokinetic conditions].
The influence of hypokinesia on phospholipid composition of the brain tissue was investigated. Hypokinesia was found to cause significant disorders in the phospholipid composition. Changes exhibit a phase character and are more pronounced on the 15-th and 30-th days of hypokinesia. The use of GABA and pyracetam promotes the processes aimed at normalization of the phospholipid metabolism in the brain tissue.
Akopian
V P
VP
Sotskiĭ
O P
OP
Oveian
G A
GA
Edigarova
L V
LV
D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D001923:Brain Chemistry / Q000187:drug effects; D002855:Chromatography, Thin Layer; D004353:Drug Evaluation, Preclinical; D018476:Hypokinesia / Q000188:drug therapy* / Q000378:metabolism; D008297:Male; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D010743:Phospholipids / Q000032:analysis / Q000378:metabolism*; D010889:Piracetam / Q000627:therapeutic use*; D051381:Rats; D013997:Time Factors; D005680:gamma-Aminobutyric Acid / Q000627:therapeutic use*
D018696:Neuroprotective Agents; D010743:Phospholipids; D005680:gamma-Aminobutyric Acid; D010889:Piracetam
Vliianie GAMK i piratsetama na kachestvennyĭ i kolichestvennyĭ sostav fosfolipidov golovnogo mozga krys v usloviiakh gipokinezii.