title: [Cancer incidence in persons with a mental handicap; possibly increased risk of esophageal cancer].
abstract: OBJECTIVE
  Prompted by a British study which revealed a raised frequency of oesophageal cancer as the cause of death among the mentally handicapped, a study was made of the cancer incidence among an institutionalized population with a mental handicap, which incidence was compared with that among the population in general.
  
  
  METHODS
  Retrospective follow-up study.
  
  
  METHODS
  An inventory was made of the cytologically or histologically confirmed cancer diagnoses among persons living in an institute for the mentally handicapped during 1 January 1974 through 1 January 1994 (n = 1020). The incidence figures were compared with those for the general population (Netherlands Cancer Registration 1989) after indirect standardization.
  
  
  RESULTS
  The total cancer risk among the population with a mental handicap was the same as that among the general population where women, and lower where men were concerned. This study brought to light a decreased risk of lung cancer (standardized morbidity rate (SMR): 0.33; 95% confidence interval: 0.33-0.97), while the SMR of oesophageal cancer showed no statistically significant increase.
  
  
  CONCLUSIONS
  Cancer is not more frequent among the mentally handicapped than among the general population. Nevertheless, increased attention for occurrence of oesophageal cancer appears to be still indicated.
authors.affiliation: Hooge Burch, Christelijk centrum voor mensen met een verstandelijke handicap, Zwammerdam.
authors.forename: H M
authors.initials: HM
authors.lastname: Evenhuis
authors.forename: M J
authors.initials: MJ
authors.lastname: Oostindiër
authors.forename: J W
authors.initials: JW
authors.lastname: Steffelaar
authors.forename: J W
authors.initials: JW
authors.lastname: Coebergh
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D015331:Cohort Studies; D004314:Down Syndrome / Q000150:complications; D004938:Esophageal Neoplasms / Q000150:complications; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008607:Intellectual Disability / Q000150:complications*; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications* / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors
vernacular_title: Incidentie van kanker bij mensen met een verstandelijke handicap; mogelijk verhoogd risico op slokdarmkanker.