title: Primary multiple epithelioid leiomyosarcoma of the liver.
abstract: Sarcomas represent only 1-2% of primary malignant tumors of the liver. We report the twenty first case of primary hepatic leiomyosarcoma in the literature. Metastases from gastrointestinal tract, female genital system and lung have to be excluded before confirming diagnosis of a primary neoplasm. Extensive involvement of the liver parenchyma contraindicated surgery, the treatment of choice when the tumor is solitary or multiple but located in one lobe. Chemotherapy, as employed in our patient, is the alternative therapeutic option in inoperable cases, but its role has to be clarified.
authors.affiliation: Department of General and Oncologic Surgery, Ospedale Maggiore Polilinico of Milan, University of Milan, Italy.
authors.forename: U
authors.initials: U
authors.lastname: Cioffi
authors.forename: P
authors.initials: P
authors.lastname: Quattrone
authors.forename: M
authors.initials: M
authors.lastname: De Simone
authors.forename: L
authors.initials: L
authors.lastname: Bonavina
authors.forename: A
authors.initials: A
authors.lastname: Segalin
authors.forename: T
authors.initials: T
authors.lastname: Masini
authors.forename: M
authors.initials: M
authors.lastname: Montorsi
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000188:drug therapy / Q000473:pathology*; D008113:Liver Neoplasms / Q000188:drug therapy / Q000473:pathology*