title: Cyclosporine delays host immune response to antibody enzyme conjugate in ADEPT.
authors.affiliation: Department of Surgery, Charing Cross Hospital, London, England.
authors.forename: K D
authors.initials: KD
authors.lastname: Bagshawe
authors.forename: S K
authors.initials: SK
authors.lastname: Sharma
mesh_terms: D000230:Adenocarcinoma / Q000276:immunology / Q000628:therapy*; D000328:Adult; D000368:Aged; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D000917:Antibody Formation / Q000187:drug effects; D003110:Colonic Neoplasms / Q000276:immunology / Q000628:therapy; D015179:Colorectal Neoplasms / Q000276:immunology / Q000628:therapy*; D016572:Cyclosporine / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis / Q000097:blood; D007075:Immunoglobulin M / Q000096:biosynthesis / Q000097:blood; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D007167:Immunotherapy; D008875:Middle Aged; D010865:Pilot Projects; D011355:Prodrugs / Q000378:metabolism / Q000627:therapeutic use*; D012004:Rectal Neoplasms / Q000276:immunology / Q000628:therapy; D011623:gamma-Glutamyl Hydrolase / Q000008:administration & dosage / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007166:Immunosuppressive Agents; D011355:Prodrugs; D016572:Cyclosporine; D011623:gamma-Glutamyl Hydrolase