[Longitudinal study of 24-hour blood pressure behavior in pregnancy and puerperium in patients with normal pregnancy, pre-eclampsia and HELLP syndrome].
Ante- and postpartum noninvasive 24-hour ambulatory blood pressure measurements were performed in 18 normotensive pregnants and 36 patients with mild (n = 16) or severe preeclampsia (n = 12) or HELLP-syndrome (n = 8). In contrast to normotensive pregnancy (n = 18) displaying a decline of systolic and diastolic blood pressure in comparison with normotensive non-pregnant, preeclamptic women demonstrate significantly elevated blood pressure profiles before delivery that remain elevated up to the eighth week postpartum. 9 out of 12 patients with severe preeclampsia and 6 of 8 women with HELLP-syndrome show a nocturnal increase of blood pressure within the first week postpartum and a non-dipping up to the eighth week after delivery. As a result of this, in preeclamptic women blood pressure control should be extended into the night and antihypertensive therapy should include a sufficient evening dose.
Ruschitzka
F
F
Abteilung Nephrologie und Rheumatologie, Medizinische Universitätsklinik, Göttingen.
Schulz
E
E
Kling
H
H
Schrader
J
J
Rath
W
W
D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D015924:Blood Pressure Monitors; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D017359:HELLP Syndrome / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000503:physiopathology*; D007231:Infant, Newborn; D008137:Longitudinal Studies; D011225:Pre-Eclampsia / Q000175:diagnosis / Q000503:physiopathology*; D011247:Pregnancy; D011644:Puerperal Disorders / Q000175:diagnosis / Q000503:physiopathology*; D012016:Reference Values
Longitudinalstudie zum 24-Stunden-Blutdruckverhalten in Schwangerschaft und Wochenbett bei Patientinnen mit normaler Schwangerschaft, Präeklampsie und HELLP-Syndrom.