title: [Comparative study of inactivated cultured vaccines against tick-borne encephalitis manufactured in Russia and in Austria by the "Immuno" firm].
abstract: Inactivated culture vaccine against tick-borne encephalitis (TBE) FSME-Immun-Inject produced in Austria ("Immuno") was compared to vaccine produced in the Institute of Poliomyelitis and viral encephalitis by immunological activity, safety, reactogenicity. In mice, no significant differences in protective activity of the vaccines were found when test-strains were diverse strains of TBE virus. Seroconversion in the sera from the vaccinated two times was not significantly different by the level of antibodies determined for both eastern and western serotypes of TBE virus.
authors.forename: M S
authors.initials: MS
authors.lastname: Vorob'eva
authors.forename: M N
authors.initials: MN
authors.lastname: Rasshchepkina
authors.forename: I P
authors.initials: IP
authors.lastname: Ladyzhenskaia
authors.forename: M A
authors.initials: MA
authors.lastname: Gorbunov
authors.forename: L I
authors.initials: LI
authors.lastname: Pavlova
authors.forename: T A
authors.initials: TA
authors.lastname: Bektimirov
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D001317:Austria; D004669:Encephalitis Viruses, Tick-Borne / Q000276:immunology*; D004675:Encephalitis, Tick-Borne / Q000276:immunology / Q000517:prevention & control*; D006385:Hemagglutination Inhibition Tests; D007124:Immunoenzyme Techniques; D051379:Mice; D008807:Mice, Inbred BALB C; D012426:Russia; D014611:Vaccination; D015164:Vaccines, Inactivated / Q000276:immunology; D014765:Viral Vaccines / Q000276:immunology; D014776:Virus Cultivation
chemical_list: D000914:Antibodies, Viral; D015164:Vaccines, Inactivated; D014765:Viral Vaccines
vernacular_title: Sravnitel'noe izuchenie inaktivirovannykh kul'tural'nykh vaktsin protiv kleshchevogo 7entsefalita otechestvennogo proizvodstva i proizvodstva firmy "Immuno" (Avstriia).