title: [Primary antiphospholipid antibody syndrome in pregnancy--successful pregnancy outcome after intravenous immunoglobulin administration].
abstract: Primary antiphospholipid antibody syndrome is characterized by intrauterine fetal death and arterial and/or venous thrombosis. The clinical course of a 37-year-old pregnant woman with a history of eight previous miscarriages is presented. By application of intravenous immunoglobulin (Venimmun Behringwerke Marburg/Lahn) a successful pregnancy could be accomplished. Diagnosis, immunologic pathomechanisms, possible treatment modalities as well as the obstetric management of this autoimmune disease will be discussed.
authors.affiliation: Ludwig-Boltzmann-Institut für Klinische Geburtshilfe u. Gynäkologie, SMZ-Ost Donauspital, Wien.
authors.forename: A C
authors.initials: AC
authors.lastname: Rosen
authors.forename: B
authors.initials: B
authors.lastname: Anegg
mesh_terms: D000026:Abortion, Habitual / Q000209:etiology / Q000517:prevention & control; D000328:Adult; D016736:Antiphospholipid Syndrome / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D007074:Immunoglobulin G / Q000008:administration & dosage*; D007231:Infant, Newborn; D011247:Pregnancy; D011256:Pregnancy Outcome
chemical_list: C021306:IgG, sulfonated; D007074:Immunoglobulin G
vernacular_title: Das primäre Antiphospholipid-Antikörper-Syndrom (APAK) in der Schwangerschaft--erfolgreicher Schwangerschaftsverlauf nach intravenöser Immunglobulingabe (IVIG).