Neuro-Behçet disease presenting with internuclear ophthalmoplegia.
OBJECTIVE
To report a case of isolated internuclear ophthalmoplegia in a patient with neuro-Behçet's disease.


METHODS
We evaluated the patient's clinical course.


RESULTS
The patient had isolated internuclear ophthalmoplegia and headache. Subsequent cerebrospinal fluid study revealed marked pleocytosis predominated by lymphocytes (61%) and polymorphonuclear cells (35%), increased protein content, and normal glucose level. A magnetic resonance imaging study with T2-weighted image demonstrated a hyperintense area in the medial longitudinal fasciculus.


CONCLUSIONS
Colchicine treatment of neuro-Behçet's disease caused marked improvement in the symptoms in this case, and the midbrain lesion completely disappeared after treatment.
Masai
H
H
Department of Ophthalmology, Faculty of Medicine, Kyoto University, Japan.
Kashii
S
S
Kimura
H
H
Fukuyama
H
H
D000208:Acute Disease; D000328:Adult; D001528:Behcet Syndrome / Q000175:diagnosis*; D001921:Brain / Q000473:pathology; D002555:Cerebrospinal Fluid / Q000166:cytology; D003078:Colchicine / Q000627:therapeutic use; D004172:Diplopia / Q000175:diagnosis; D006074:Gout Suppressants / Q000627:therapeutic use; D006801:Humans; D008214:Lymphocytes / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D009504:Neutrophils / Q000473:pathology; D009886:Ophthalmoplegia / Q000175:diagnosis*; D014792:Visual Acuity
D006074:Gout Suppressants; D003078:Colchicine