title: [Histiocytosis X and ankylosing spondylitis. A common pathogenesis?].
abstract: Histiocytosis X is considered a group of diseases of unknown origin. Nevertheless, the presence of certain lymphocytes disorders and immunocomplexes has permitted us to think that it is an immunologic disease. The ankylosing spondylitis is also a disease of unknown origin, but like the histiocytosis X, might be of immunologic origin. In both entities, a defect of T-lymphocytes has been demonstrated. We present a patient in whom both diseases are associated, which is not reported before in the medical literature. We think that these disorders may be related by a common immunologic alteration.
authors.affiliation: Servicio de Neumología, Hospital La Paz, Universidad Autónoma, Madrid.
authors.forename: R
authors.initials: R
authors.lastname: Alvarez-Sala
authors.forename: C
authors.initials: C
authors.lastname: Prados
authors.forename: E
authors.initials: E
authors.lastname: de Miguel
authors.forename: I
authors.initials: I
authors.lastname: García-Talavera
authors.forename: J
authors.initials: J
authors.lastname: Muñoz
mesh_terms: D000328:Adult; D001327:Autoimmune Diseases / Q000276:immunology; D004198:Disease Susceptibility / Q000276:immunology; D015796:HLA-B27 Antigen / Q000032:analysis; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications / Q000276:immunology*; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000276:immunology; D008297:Male; D013167:Spondylitis, Ankylosing / Q000150:complications / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D015796:HLA-B27 Antigen
vernacular_title: Histiocitosis X y espondilitis anquilosante. Patogenia común?