Oral ivermectin paste for the treatment of chorioptic mange in horses.
A single blind controlled clinical trial of oral ivermectin paste at a dose rate of 0.1 mg/kg daily for seven days for the treatment of chorioptic mange in horses was carried out. There was a statistically significant reduction in the numbers of mites in the samples taken from the treated horses compared with the untreated horses, but the mites were not eliminated from all the treated animals. Two further groups of horses were treated, one at a dose rate of 0.1 mg/kg daily for 10 days and the other with two doses of 0.2 mg/kg given two weeks apart. There were no statistically significant differences between any of the three treatment groups, and none of the treatments eliminated mites from all the treated horses.
Littlewood
J D
JD
Centre for Small Animal Studies, Animal Health Trust, Newmarket, Suffolk.
Rose
J F
JF
Paterson
S
S
D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D006734:Horse Diseases / Q000188:drug therapy*; D006736:Horses; D007559:Ivermectin / Q000627:therapeutic use*; D008297:Male; D008924:Mite Infestations / Q000188:drug therapy / Q000662:veterinary*; D016037:Single-Blind Method
D007559:Ivermectin