title: [Correction of myopia using laser in situ keratomileusis (LASIK)].
abstract: BACKGROUND
  In contrast to photorefractive keratectomy (PRK), the corneal epithelium and Bowman's layer are preserved in LASIK. Thus, there should be less scarring and regression after LASIK than after PRK.
  
  
  METHODS
  Between December 1993 and October 1995, we treated 113 eyes (66 patients). The Automated Corneal Shaper and the Keracor 116 excimer laser were used. We evaluated refraction, visual acuity and corneal topography.
  
  
  RESULTS
  To date, 61 eyes reached six months follow up. Mean preoperative refraction was -14.3 D (-3.3 to -29 D; SD = 7). Mean deviation from target refraction was -1.4 D (-9.5 to +2.5 D; SD = 2.7) at six months. 34% were within +/-0.5 D of target refraction, 46% within +/-1 D, 67% within +/-2 D, and 82% within +/-3 D. Mean change of refraction ("regression") from one to six months postoperatively was +0.13 D (-7.5 to +8 D; SD = 2.1). Refractive change was < 0.5 D in 51%, < 1 D in 66%, < 2 D in 84%, and < 3 D in 89%. In 88% of eyes, the corneal interface was not or just barely visible, while it was clearly visible in 12%. No scars were observed.
  
  
  CONCLUSIONS
  Our results indicate that LASIK is an effective procedure in the correction of high myopia. The incidence of scar formation and regression is considerably lower than after PRK.
authors.affiliation: Universitätsaugenklinik, Klinikum Mannheim.
authors.forename: M C
authors.initials: MC
authors.lastname: Knorz
authors.forename: A
authors.initials: A
authors.lastname: Liermann
authors.forename: B
authors.initials: B
authors.lastname: Wiesinger
authors.forename: V
authors.initials: V
authors.lastname: Seiberth
authors.forename: H
authors.initials: H
authors.lastname: Liesenhoff
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002921:Cicatrix / Q000473:pathology; D003315:Cornea / Q000473:pathology; D005260:Female; D006801:Humans; D054018:Lasers, Excimer; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D018903:Photorefractive Keratectomy / Q000295:instrumentation*; D011183:Postoperative Complications / Q000473:pathology; D011446:Prospective Studies; D012029:Refraction, Ocular; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology
vernacular_title: Myopiekorrektur mittels Laser in situ Keratomileusis (LASIK).