title: The expanded role of randomized clinical trials.
authors.forename: C
authors.initials: C
authors.lastname: Kupfer
mesh_terms: D003362:Cost-Benefit Analysis; D006305:Health Status Indicators; D006801:Humans; D009316:National Institutes of Health (U.S.); D009885:Ophthalmology / Q000639:trends*; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic / Q000639:trends*; D013673:Technology Assessment, Biomedical; D014481:United States