Malononitrilamides inhibit T- and B-cell responsiveness.
Kurrle
R
R
Research Laboratories, Hoechst AG, Marburg, Germany.
Bartlett
R
R
Ruuth
E
E
Lauffer
L
L
Schorlemmer
H U
HU
D000480:Alkynes; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D001402:B-Lymphocytes / Q000187:drug effects* / Q000276:immunology; D002478:Cells, Cultured; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis; D007075:Immunoglobulin M / Q000096:biosynthesis; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D015847:Interleukin-4 / Q000494:pharmacology; D007555:Isoxazoles; D008213:Lymphocyte Activation / Q000187:drug effects*; D051379:Mice; D009570:Nitriles / Q000494:pharmacology*; D051381:Rats; D013154:Spleen; D013601:T-Lymphocytes / Q000187:drug effects* / Q000276:immunology
D000480:Alkynes; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007166:Immunosuppressive Agents; D007555:Isoxazoles; D009570:Nitriles; C102911:X 910279; C115284:2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide; D015847:Interleukin-4