title: Screening of in vitro antibacterial activity from Syzygium Guineense (Willd) hydrosoluble dry extract.
abstract: Diarrhoea is one of the most important causes of infant mortality in the world. As modern drugs are expensive or unavailable in developing countries, many people use traditional medicines in Africa for the treatment of several diseases. In our study, we investigated the antibacterial activity of Syzygium Guineense extract in order to assess its activity on some bacterial strains involved in diarrhoeal diseases and to justify its use. The aqueous dry extract was prepared by decoction followed by evaporating to dryness and tested according to dilution method. This extract showed an antibacterial activity against some bacterial strains: Salmonella E., Shigella D., Shigella F., E. Coli., Enterobacter A. It did not show any activity against Citrobacter F., Proteus M., Klebsiella P. Storage conditions (27 degrees C, glass flask) did not affect antibacterial properties of the extract.
authors.affiliation: Laboratoire de Pharmacie galénique, Faculté de Pharmacie, Kinshasa XI, Zaïre.
authors.forename: T M
authors.initials: TM
authors.lastname: Tsakala
authors.forename: O
authors.initials: O
authors.lastname: Penge
authors.forename: K
authors.initials: K
authors.lastname: John
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D016971:Citrobacter freundii / Q000187:drug effects; D004926:Escherichia coli / Q000187:drug effects; D066298:In Vitro Techniques; D007711:Klebsiella pneumoniae / Q000187:drug effects; D010936:Plant Extracts / Q000494:pharmacology*; D011513:Proteus mirabilis / Q000187:drug effects; D012477:Salmonella enteritidis / Q000187:drug effects; D012762:Shigella dysenteriae / Q000187:drug effects; D012763:Shigella flexneri / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D010936:Plant Extracts