Taste-modifying triterpene glycosides from Staurogyne merguensis.
Five new oleanane-type triterpene glycosides named strogins 1-5 were isolated from leaves of Staurogyne merguensis. Their structures were determined on the basis of chemical and spectral evidence. After strogins 1, 2 and 4 were held in mouth, water elicited a sweet taste. On the other hand, strogins 3 and 5 had no activity. The structure-activity relationship is discussed.
Hiura
A
A
Department of Chemistry, Faculty of Education, Yokohama National University, Japan.
Akabane
T
T
Ohtani
K
K
Kasai
R
R
Yamasaki
K
K
Kurihara
Y
Y
D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013329:Structure-Activity Relationship; D013649:Taste / Q000187:drug effects*
D006027:Glycosides