Bioinformatics in the pharmaceutical industry.
The great advances in human healthcare that are presaged by the Human Genome Project can be realized by the pharmaceutical industry. A prerequisite for this will be the successful integration of bioinformatics into most aspects of drug discovery. Although, from a scientific viewpoint, this is not a difficult problem, there are formidable technological obstacles. Once these are overcome, rapid progress can be expected.
Lyall
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Glaxo Wellcome Research and Development, Medicines Research Centre, Stevenage, Hertfordshire, UK. al28044@ggr.co.uk
D000595:Amino Acid Sequence; D016282:Aspartic Acid Endopeptidases / Q000235:genetics; D001709:Biotechnology / Q000639:trends; D019295:Computational Biology / Q000639:trends*; D003198:Computer Simulation; D015195:Drug Design; D004353:Drug Evaluation, Preclinical; D004345:Drug Industry / Q000639:trends*; D016333:HIV Protease / Q000737:chemistry; D016045:Human Genome Project; D006801:Humans; D008954:Models, Biological; D008969:Molecular Sequence Data; D012190:Retroviridae / Q000201:enzymology / Q000235:genetics; D017386:Sequence Homology, Amino Acid
D016282:Aspartic Acid Endopeptidases; D016333:HIV Protease