title: Neonatal and infantile upper gastrointestinal endoscopy using a new small diameter fibreoptic gastroscope.
abstract: Using a new prototype (Olympus XPGIF 5.2/ N30) gastroscope, upper gastrointestinal endoscopy was safely performed under sedation on 99 infants (weights 0.9 to 10.1 kg). No complications occurred. Macroscopic and microscopic abnormalities were found in 60%, including abnormal duodenal biopsies in 47% of cases with protracted diarrhoea. Duodenal biopsy material was, however, of suboptimal standard for histologic assessment in 25% of the cases. In 52% of those under 3.5 kg diagnoses were made that would not have otherwise been possible and, in 75% of those in the Intensive Care Unit, abnormalities were found. The use of this new endoscope represents a significant advance in clinical practice.
authors.affiliation: Hospital for Sick Children, London, U.K.
authors.forename: T
authors.initials: T
authors.lastname: Ruuska
authors.forename: J M
authors.initials: JM
authors.lastname: Fell
authors.forename: W M
authors.initials: WM
authors.lastname: Bisset
authors.forename: P J
authors.initials: PJ
authors.lastname: Milla
mesh_terms: D001706:Biopsy; D004386:Duodenum / Q000473:pathology; D020776:Endoscopes, Gastrointestinal; D005336:Fiber Optic Technology; D005767:Gastrointestinal Diseases / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015931:Intensive Care, Neonatal