title: Comparative study of diclofenac sodium and flurbiprofen in osteoarthritis.
abstract: A comparative study was conducted to evaluate the therapeutic efficacy of diclofenac sodium and flurbiprofen both non-steroidal anti-inflammatory drugs (NSAIDS) in osteoarthritis. Forty patients of either sex between the ages of 35-60 years suffering from osteoarthritis of at least one knee joint minimum of eight weeks duration were included in the study. Diclofenac sodium exhibited better results by improving the signs and symptoms of osteoarthritis in both high and low doses compared to flurbiprofen. The adverse effects observed were similar in both groups.
authors.affiliation: Department of Pharmacology, Dow Medical College, BMSI, Karachi.
authors.forename: K A
authors.initials: KA
authors.lastname: Shaikh
authors.forename: M
authors.initials: M
authors.lastname: Ali
authors.forename: T
authors.initials: T
authors.lastname: Sharafatullah
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D004008:Diclofenac / Q000627:therapeutic use*; D005260:Female; D005480:Flurbiprofen / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D010003:Osteoarthritis / Q000188:drug therapy*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004008:Diclofenac; D005480:Flurbiprofen