title: [Clinical findings and pathology of congenital polycystic renal disease in the goat].
abstract: The clinical and pathomorphological findings of the spongy (cases 1, 2 and 3) and large-vacuol polycystic kidney disease in four kids are presented. The age of the goats ranged from one week to three months. In case 1 clinical examination including laboratory testing was performed, whereas in cases 2, 3 and 4 only the kidneys were available. Based upon the neurological examination a forebrain lesion was localized in case 1. Laboratory examinations revealed an azotemia and uremic encephalopathy was suspected. Gross pathology demonstrated bilateral polycystic kidneys and proliferation and ectasy of the intrahepatic choledochus system. Histopathology of the brain showed multiple alterations, such as malacia, edema, inflammation and a hemorrhagic area. As in other species, a genetical background of the disease is suspected because the twin of case 1 demonstrated similar symptoms.
authors.affiliation: Institut für Tierneurologie, Universität Bern.
authors.forename: F
authors.initials: F
authors.lastname: Steffen
authors.forename: A
authors.initials: A
authors.lastname: Tontis
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001921:Brain / Q000473:pathology*; D002455:Cell Division; D004848:Epithelium / Q000473:pathology; D005260:Female; D005704:Gallbladder / Q000473:pathology; D015511:Goat Diseases; D006041:Goats; D007668:Kidney / Q000473:pathology*; D008099:Liver / Q000473:pathology*; D007690:Polycystic Kidney Diseases / Q000151:congenital / Q000175:diagnosis / Q000662:veterinary*