title: Postprandial lipemia in obese men with abdominal fat patterning.
abstract: OBJECTIVE
  The purpose of this study was to assess differences in measures of postprandial triglyceride (TG) clearance between obese men with abdominal fat patterning (OAF) and men of desirable weight (DW). It was hypothesized that the OAF men would have impaired postprandial TG clearance.
  
  
  METHODS
  A comparative design was used.
  
  
  METHODS
  Data were collected in a research laboratory with access to blood analysis instrumentation.
  
  
  METHODS
  Fourteen healthy, physically active, normolipemic men (7 OAF and 7 DW) were studied.
  
  
  METHODS
  Each subject consumed an oral fat load (78 grams of fat) and blood samples were collected every hour for 8 hours.
  
  
  METHODS
  Measures of postprandial lipemia included: incremental TG area, total TG area, time to peak TG concentration, maximal change in TG concentration, and time to return to baseline TG concentration.
  
  
  RESULTS
  OAF men had significantly greater total area under the TG curve (24.7 +/- 1.09 vs 16.1 +/- 1.3 mmol-L(-1).8 hours, p = 0.003) and greater maximum TG change (2.0 +/- 0.3 vs 1.2 +/- 0.2 mmol-L-1, p = 0.03) following the oral fat load. Additionally, the total area under the TG curve was positively correlated with baseline TG concentrations (r = 0.53) and inversely correlated with baseline HDL2 concentrations (r = 0.64). Baseline HDL2 concentrations were inversely correlated with time to return to TG baseline (r = 0.57).
  
  
  CONCLUSIONS
  Normal fasting lipoprotein profiles and regular physical activity do not preclude OAF men from having pronounced postprandial lipemia.
authors.affiliation: Ball State University, Adult Physical Fitness Program, Muncie, Indiana, USA.
authors.forename: L
authors.initials: L
authors.lastname: Wideman
authors.forename: L A
authors.initials: LA
authors.lastname: Kaminsky
authors.forename: M H
authors.initials: MH
authors.lastname: Whaley
mesh_terms: D015992:Body Mass Index; D004041:Dietary Fats / Q000008:administration & dosage*; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood*
chemical_list: D004041:Dietary Fats; D008074:Lipoproteins