[Acute pituitary necrosis after multiple pituitary stimulation test].
Iatrogenic necrosis of the pituitary gland is well-known but rarely caused by stimulation tests used to investigate pituitary adenomas; 26 cases have been reported in the literature. We report 2 new cases where the chronology of the events suggests the sudden necrosis resulted from stimulation tests. Several mechanisms have been proposed. It is not possible to define increased risk as a function of the adenoma histology. In most cases, voluminous tumors are revealed by visual dysfunction. These accidents should not overshadow the role of function tests in neurosurgical situations. Outcome is usually favorable after acute necrosis.
Vergély
N
N
Service d'Endocrinologie, Hôpital de Bellevue, CHU de Saint-Etienne.
Millot
L
L
Brulport
V
V
Duthel
R
R
Estour
B
B
D000208:Acute Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010901:Pituitary Function Tests / Q000009:adverse effects*; D010902:Pituitary Gland / Q000473:pathology*