title: Antibiotic prophylaxis in umbilical and incisional hernia repair: a prospective randomised study.
abstract: OBJECTIVE
  To find out if preoperative prophylaxis would reduce infection rates after umbilical and incisional hernia repair.
  
  
  METHODS
  Randomised controlled trial.
  
  
  METHODS
  Teaching hospital, Israel.
  
  
  METHODS
  35 Patients who presented with umbilical (n = 19) or incisional (n = 16) hernias during a period of 8 months.
  
  
  METHODS
  Cefonicid 1 g was given by intravenous infusion to alternate patients 30 minutes before the operation.
  
  
  METHODS
  Wound infection.
  
  
  RESULTS
  The groups were comparable for age, body mass index, grade of surgeon, operating time, and size of hernial ring. The wound infection rates were 0/8 compared with 4/8 for incisional hernia repairs (p = 0.08) and 1/9 compared with 4/10 for umbilical hernia repairs (p = 0.3). The overall rate was 1/17 compared with 8/18 (p = 0.02).
  
  
  CONCLUSIONS
  Single dose antibiotic puphylaxis seems to exert a beneficial effect on the wound infection rate after umbilical and incisional hernia repair.
authors.affiliation: Department of Surgery A and B, Shaare Zedek Medical Center, Jerusalem, Israel.
authors.forename: D
authors.initials: D
authors.lastname: Abramov
authors.forename: I
authors.initials: I
authors.lastname: Jeroukhimov
authors.forename: A M
authors.initials: AM
authors.lastname: Yinnon
authors.forename: Y
authors.initials: Y
authors.lastname: Abramov
authors.forename: E
authors.initials: E
authors.lastname: Avissar
authors.forename: Z
authors.initials: Z
authors.lastname: Jerasy
authors.forename: O
authors.initials: O
authors.lastname: Lernau
mesh_terms: D000328:Adult; D019072:Antibiotic Prophylaxis; D015790:Cefonicid / Q000627:therapeutic use*; D002511:Cephalosporins / Q000627:therapeutic use*; D006554:Hernia, Umbilical / Q000601:surgery*; D006555:Hernia, Ventral / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D011300:Preoperative Care; D011446:Prospective Studies; D013530:Surgical Wound Infection / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D002511:Cephalosporins; D015790:Cefonicid