Evaluation of radioiodo-4-amino-N-[1-[3-(4-fluorophenoxy)-propyl]-4- methyl-4-piperidinyl]-5-iodo-2-methoxybenzamide as a potential 5HT2 receptor tracer for SPE(C)T.
Terriere
D
D
Janssen Research Foundation, Beerse, Belgium.
Janssen
P M
PM
Gommeren
W
W
Gysemans
M
M
Mertens
J J
JJ
Leysen
J E
JE
D000818:Animals; D001667:Binding, Competitive / Q000187:drug effects; D001921:Brain / Q000378:metabolism; D066298:In Vitro Techniques; D007553:Isotope Labeling; D007650:Ketanserin / Q000493:pharmacokinetics; D008297:Male; D008566:Membranes / Q000378:metabolism; D011849:Radioactive Tracers; D011869:Radioligand Assay; D051381:Rats; D017208:Rats, Wistar; D011985:Receptors, Serotonin / Q000187:drug effects*; D016713:Ritanserin / Q000493:pharmacokinetics; D018490:Serotonin Agents / Q000493:pharmacokinetics; D012702:Serotonin Antagonists / Q000493:pharmacokinetics; D015899:Tomography, Emission-Computed, Single-Photon
D011849:Radioactive Tracers; D011985:Receptors, Serotonin; D018490:Serotonin Agents; D012702:Serotonin Antagonists; D016713:Ritanserin; D007650:Ketanserin