title: [Primary hyperparathyroidism--diagnostic problems].
abstract: Parathyroid imaging with 99m Tc-MIBI, introduced at the beginning of the 90's seems to be a promising method for parathyroid adenomas localization. The aim of the study was to assess the efficacy of parathyroid imaging with 99m Tc-MIBI for preoperative localization of parathyroid adenomas and to compare that method with the high-resolution ultrasonography. Thirteen patients with primary hyperparathyroidism of duration from 2 to 25 years were included in the study. The presence of parathyroid adenomas was confirmed by histopathology in all patients. The sensitivity for scintigraphy and ultrasonography was 92.8% and 78.5%, the number of false positive results was 0 and 2 and false negative-0 and 1, respectively. Parathyroid imaging with 99m Tc-MIBI is a useful method for parathyroid adenomas localization, and in contrast to ultrasonography its sensitivity does not decrease if a parathyroid adenoma is located ectopically. Nevertheless, because of the greater accessibility, lower costs and its simplicity ultrasonography should be used as a screening modality for parathyroid adenoma localization.
authors.affiliation: Klinika Endokrynologii AM w Poznaniu.
authors.forename: W
authors.initials: W
authors.lastname: Horst-Sikorska
authors.forename: D
authors.initials: D
authors.lastname: Baszko-Błaszczyk
authors.forename: M
authors.initials: M
authors.lastname: Drews
authors.forename: R
authors.initials: R
authors.lastname: Junik
authors.forename: L
authors.initials: L
authors.lastname: Pietz
authors.forename: M
authors.initials: M
authors.lastname: Gembicki
authors.forename: J
authors.initials: J
authors.lastname: Kosowicz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000000981:diagnostic imaging* / Q000517:prevention & control; D008297:Male; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi; D014463:Ultrasonography
chemical_list: D017256:Technetium Tc 99m Sestamibi