Transmission of Citrobacter koseri from mother to infant documented by ribotyping and pulsed-field gel electrophoresis.
We describe a case in which Citrobacter koseri (formerly C. diversus) was transmitted from a pregnant mother with chorioamnionitis and bacteremia to her infant who was bacteremic at birth and in apparent septic shock. Two highly discriminating molecular methods, ribotyping and pulsed field gel electrophoresis, were used to examine restriction fragment length polymorphisms within the genomic DNA of maternal and infant isolates. Both techniques identified the maternal and infant isolates as the same strain, distinct from epidemiologically unrelated controls, thus confirming their common origin.
Papasian
C J
CJ
Department of Pathology, Truman Medical Center University of Missouri, School of Medicine, Kansas City 64108, USA.
Kinney
J
J
Coffman
S
S
Hollis
R J
RJ
Pfaller
M A
MA
D000328:Adult; D016470:Bacteremia / Q000635:transmission; D015373:Bacterial Typing Techniques; D002954:Citrobacter; D016521:Electrophoresis, Gel, Pulsed-Field; D004756:Enterobacteriaceae Infections / Q000175:diagnosis* / Q000635:transmission*; D005260:Female; D016680:Genome, Bacterial; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D017720:Molecular Epidemiology; D010920:Placenta / Q000382:microbiology; D012150:Polymorphism, Restriction Fragment Length; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D012772:Shock, Septic / Q000175:diagnosis