title: [Autologous blood donation--good clinical practice and good recuperation practice].
abstract: Since October 1987, autologous blood donations have been performed in Bern and in 1994 reached a total of 946, representing 3% of all blood donations. This value is lower than the 4.9% for Switzerland as a whole. We report on the motivation and reasons of patients in favour of autologous blood donations and compare the results of 1989 with 1995. In the 6 years' period, the median patient's age increased from 54 to 63 years. The motivation for autologous blood donations changed from "routine surgical office" to "doctors". More than 50% of the patients mentioned the risk of acquiring an infectious disease, especially HIV, as the main reason for autologous blood donations. Labeling, testing or storage of autologous blood products of 37 out of 100 patients was incorrect, and in a another 20% an enquiry at the donation centres was needed to confirm the required quality of the autologous blood products. In 7 cases only one out of several blood bags was screened for viral diseases, and in 5 cases, unfortunately, none of the autologous blood products were tested for HIV or hepatitis B and C. Considering the negative cost-effectiveness of autologous blood transfusion, it is strongly recommended that the intrinsically low clinical benefit of autologous blood product should not be compromised by lack of good clinical practice and good manufacturing practice.
authors.affiliation: Hämatologisches Zentrallabor, Inselspital, Universitätsspital, Bern.
authors.forename: S P
authors.initials: SP
authors.lastname: Hauser
authors.forename: C
authors.initials: C
authors.lastname: Otth
authors.forename: L
authors.initials: L
authors.lastname: Franscini
authors.forename: U E
authors.initials: UE
authors.lastname: Nydegger
mesh_terms: D000328:Adult; D000368:Aged; D001804:Blood Transfusion, Autologous / Q000523:psychology / Q000592:standards; D005260:Female; D015658:HIV Infections / Q000517:prevention & control / Q000635:transmission; D006525:Hepatitis, Viral, Human / Q000517:prevention & control / Q000635:transmission; D006801:Humans; D008297:Male; D008875:Middle Aged; D009042:Motivation; D065227:Transfusion Reaction