title: [Therapy of hepatocellular carcinoma].
abstract: The therapeutic modalities in patients with hepatocellular carcinoma (HCC) depend on the number, size and location of the lesions as well as the stage of the underlying liver disease and the physical condition of the patient. In patients with small and solitary lesions, resection, liver transplantation and in some cases percutaneous ethanol injection (PEI) can be curative. In more advanced stages of the disease with larger or multiple lesions, PEI and/or transarterial chemotherapy with or without embolization (TACE or TAC) can slow the progression of the disease. In disseminated disease, a radiotherapeutic approach can be taken in selected cases. The therapeutic strategy in patients with HCCs should be individualized, frequently involving a combination of therapeutic modalities. In contrast to the earlier dismal prognosis, for most HCC patients there is today a therapeutic strategy that results in prolongation of life and in some cases even cure.
authors.affiliation: Abteilung Innere Medizin II, Medizinische Universitätsklinik, Freiburg in Breisgau.
authors.forename: H P
authors.initials: HP
authors.lastname: Allgaier
authors.forename: P
authors.initials: P
authors.lastname: Deibert
authors.forename: U
authors.initials: U
authors.lastname: Blum
authors.forename: H C
authors.initials: HC
authors.lastname: Spangenberg
authors.forename: E
authors.initials: E
authors.lastname: Moser
authors.forename: H E
authors.initials: HE
authors.lastname: Blum
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D006528:Carcinoma, Hepatocellular / Q000473:pathology / Q000628:therapy*; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic / Q000379:methods; D000431:Ethanol / Q000008:administration & dosage; D006498:Hepatectomy; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000379:methods; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D007459:Iodized Oil / Q000008:administration & dosage; D008113:Liver Neoplasms / Q000473:pathology / Q000628:therapy*; D016031:Liver Transplantation / Q000379:methods; D009367:Neoplasm Staging
chemical_list: D000970:Antineoplastic Agents; D007457:Iodine Radioisotopes; D000431:Ethanol; D007459:Iodized Oil