title: Identification of Rox3 as a component of mediator and RNA polymerase II holoenzyme.
abstract: Yeast Rox3 protein, implicated by genetic evidence in both negative and positive transcriptional regulation, is identified as a mediator subunit by peptide sequence determination and is shown to copurify and co-immunoprecipitate with RNA polymerase II holoenzyme.
authors.affiliation: Department of Structural Biology, Stanford University School of Medicine, California 94305-5400, USA.
authors.forename: C M
authors.initials: CM
authors.lastname: Gustafsson
authors.forename: L C
authors.initials: LC
authors.lastname: Myers
authors.forename: Y
authors.initials: Y
authors.lastname: Li
authors.forename: M J
authors.initials: MJ
authors.lastname: Redd
authors.forename: M
authors.initials: M
authors.lastname: Lui
authors.forename: H
authors.initials: H
authors.lastname: Erdjument-Bromage
authors.forename: P
authors.initials: P
authors.lastname: Tempst
authors.forename: R D
authors.initials: RD
authors.lastname: Kornberg
mesh_terms: D000595:Amino Acid Sequence; D005656:Fungal Proteins / Q000737:chemistry*; D015966:Gene Expression Regulation, Fungal; D046911:Macromolecular Substances; D056892:Mediator Complex; D008969:Molecular Sequence Data; D011233:Precipitin Tests; D012319:RNA Polymerase II / Q000737:chemistry*; D012441:Saccharomyces cerevisiae / Q000737:chemistry; D029701:Saccharomyces cerevisiae Proteins; D014157:Transcription Factors / Q000737:chemistry*
chemical_list: D005656:Fungal Proteins; D046911:Macromolecular Substances; D056892:Mediator Complex; C103856:ROX3 protein, S cerevisiae; D029701:Saccharomyces cerevisiae Proteins; D014157:Transcription Factors; D012319:RNA Polymerase II