title: Dietary fatty acids in athero-thrombogenesis: influence of palm oil ingestion.
abstract: Dietary experiments, performed in metabolic wards, gave rise to predictive regression equations relating changes of plasma cholesterol concentration to the intake of fatty acids of the diet. It has been established that polyunsaturated fatty acids diminish and most saturated fatty acids increase plasma cholesterol concentration. This information led to expect that dietary use of palm oil may induce an unfavorable plasma lipoprotein profile. This has not been the case as shown in various dietary experiments. The reasons for this discrepancy is discussed. The influence of palm oil enriched diets on prothrombotic variables show that platelets are not affected in their function during prolonged dietary intervention. It is important to continue research on the effects of palm oil based diet on plasma fibrinogen, factor VII. There is still discordant information in this field.
authors.affiliation: Banco Municipal de Sangre, Instituto de Medicina Experimental, Caracas, Venezuela.
authors.forename: N B
authors.initials: NB
authors.lastname: de Bosch
authors.forename: V
authors.initials: V
authors.lastname: Bosch
authors.forename: R
authors.initials: R
authors.lastname: Apitz
mesh_terms: D000328:Adult; D000818:Animals; D001161:Arteriosclerosis / Q000209:etiology* / Q000517:prevention & control; D002648:Child; D002784:Cholesterol / Q000097:blood; D004036:Diet, Atherogenic; D004041:Dietary Fats / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology*; D005167:Factor VII / Q000032:analysis; D005247:Feeding Behavior; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D005395:Fish Oils / Q000494:pharmacology; D006801:Humans; D006937:Hypercholesterolemia / Q000139:chemically induced*; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000008:administration & dosage / Q000494:pharmacology; D008074:Lipoproteins / Q000097:blood; D008297:Male; D000073878:Palm Oil; D010938:Plant Oils / Q000008:administration & dosage / Q000009:adverse effects / Q000737:chemistry / Q000494:pharmacology*; D010974:Platelet Aggregation / Q000187:drug effects; D011817:Rabbits; D012424:Rural Population; D000074242:Sunflower Oil; D013927:Thrombosis / Q000209:etiology* / Q000517:prevention & control; D014280:Triglycerides / Q000097:blood; D014505:Urban Population; D014687:Venezuela
chemical_list: D004041:Dietary Fats; D005395:Fish Oils; D008041:Linoleic Acids; D008074:Lipoproteins; D010938:Plant Oils; D000074242:Sunflower Oil; D014280:Triglycerides; D000073878:Palm Oil; D005167:Factor VII; D005340:Fibrinogen; D002784:Cholesterol; D019787:Linoleic Acid