[Cellular and humoral immunity indices in patients with myocardial infarct complicated by thromboendocarditis].
Data are submitted on the time course of immunologic indices in 50 patients with myocardial infarction (MI) presenting with complication-free course, and 58 patients with MI complicated by thromboendocarditis. Important changes were revealed in the immune status--both cellular and humoral--during the development of thrombosis of the left ventricle secondary to MI. The cellular immunity was characterized by a decline in the levels of T-lymphocytes, particularly those of T-suppressors, augmentation of B-lymphocytes. Thrombosis evolving in MI was associated with changes in humoral immunity, such as persistent and lasting rise in immunoglobulins of all classes, especially Ig G, as well as combinations thereof, together with the increase in the content of circulating immune complexes.
Simakov
A A
AA
Panfilov
Iu A
IuA
Kriukov
N N
NN
D000704:Analysis of Variance; D000917:Antibody Formation; D004696:Endocarditis / Q000209:etiology* / Q000276:immunology*; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications* / Q000276:immunology*; D013927:Thrombosis / Q000209:etiology* / Q000276:immunology*; D013997:Time Factors