Is intensive follow-up for early detection of tumors effective in children with Beckwith-Wiedemann syndrome?
Two cases of Beckwith-Wiedemann syndrome who developed malignant tumor and eventually died are reported. The patients followed two different screening programs for early detection of cancer, and the most appropriate schedule of follow-up in carriers of this syndrome is discussed.
Di Cataldo
A
A
Department of Pediatric Hematology/Oncology, University of Catania, Italy.
Haupt
R
R
Fabietti
P
P
Schilirò
G
G
D001506:Beckwith-Wiedemann Syndrome / Q000401:mortality / Q000503:physiopathology*; D002675:Child, Preschool; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male