title: [Health care economics evaluation of inpatient treatment of venous thrombosis with unfractionated heparin versus subcutaneous low molecular weight heparin at home].
abstract: BACKGROUND
  An intravenous course of unfractionated heparin as initial treatment is the standard method to treat venous thromboembolism. Increasing scientific knowledge indicates that subcutaneous low-moleculare-weight heparin is just as effective and save as unfractionated heparin. A possible advantage of low-moleculare-weight heparin is the cost saving potential in minor hospitalisation days. Both therapies will be continued for at least three months with an oral anticoagulative. Because hospitalisation belongs to the cost-intensivest factors in the German health care system the question of a health economic difference between both initial treatments raises.
  
  
  METHODS
  We transformed published empirical evidences to the German health care system, valued them in a cost analysis for a hypothetical cohort of 100 patients and compared the outcome intertherapeutically.
  
  
  CONCLUSIONS
  From perspective of sickness insurance fund as cost unit we estimate that a partial in hospital initial treatment with subcutaneous low-moleculare-weight heparin is more cost-effective than a total in-hospital initial treatment with unfractionated heparin.
authors.affiliation: Medizinische Klinik, Klinikum Innenstadt der Ludwig-Maximilians- Universität München.
authors.forename: D
authors.initials: D
authors.lastname: Osterkorn
authors.forename: W
authors.initials: W
authors.lastname: Schramm
authors.forename: T
authors.initials: T
authors.lastname: Szucs
mesh_terms: D003362:Cost-Benefit Analysis; D005858:Germany; D006493:Heparin / Q000008:administration & dosage* / Q000191:economics; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage* / Q000191:economics; D018575:Home Care Services, Hospital-Based / Q000191:economics*; D006801:Humans; D007262:Infusions, Intravenous; D007279:Injections, Subcutaneous; D007902:Length of Stay / Q000191:economics; D010343:Patient Admission / Q000191:economics*; D011446:Prospective Studies; D013924:Thrombophlebitis / Q000188:drug therapy* / Q000191:economics
chemical_list: D006495:Heparin, Low-Molecular-Weight; D006493:Heparin