title: Chronic sputum production: correlations between clinical features and findings on high resolution computed tomographic scanning of the chest.
abstract: BACKGROUND
  There are few published data on the correlation between the clinical findings in subjects with chronic sputum production and the appearances on high resolution computed tomographic (HRCT) scans of the chest.
  
  
  METHODS
  HRCT scanning of the chest was performed on 40 subjects with chronic sputum production. Three readers independently reported the scans for the presence or absence of bronchiectasis and the extent of bronchiectasis on the basis of the percentage of involved bronchi in each lobe. Relationships were sought between these findings and the clinical history, physical examination, and laboratory investigations.
  
  
  RESULTS
  HRCT scanning showed that 27 subjects had bronchiectasis. Of the clinical features only the continual production of purulent sputum and childhood pertussis were associated with bronchiectasis. There was a positive correlation between the extent of bronchiectasis and dyspnoea, and a negative correlation with forced expiratory volume in one second but not with forced vital capacity.
  
  
  CONCLUSIONS
  These results indicate that, in subjects with chronic sputum production, only a few clinical features show any correlation with the presence or extent of bronchiectasis as visualised on HRCT scans.
authors.affiliation: Department of Respiratory Medicine, Papworth Hospital, Cambridge, UK.
authors.forename: I E
authors.initials: IE
authors.lastname: Smith
authors.forename: E
authors.initials: E
authors.lastname: Jurriaans
authors.forename: S
authors.initials: S
authors.lastname: Diederich
authors.forename: N
authors.initials: N
authors.lastname: Ali
authors.forename: J M
authors.initials: JM
authors.lastname: Shneerson
authors.forename: C D
authors.initials: CD
authors.lastname: Flower
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001987:Bronchiectasis / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D002908:Chronic Disease; D004417:Dyspnea / Q000150:complications; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012044:Regression Analysis; D012720:Severity of Illness Index; D012907:Smoking / Q000009:adverse effects; D013183:Sputum; D014057:Tomography, X-Ray Computed; D014917:Whooping Cough / Q000150:complications