Effect of diets containing different amounts of precursor and derivative fatty acids on serum TXB2.
Dietary precursor and derivative polyunsaturated fatty acids influence metabolic parameters, such as eicosanoid synthesis. We have studied the effect of dietary intakes of lipids containing different amounts of precursor and derivative fatty acids (olive oil, olive-blackcurrant-fish oil mixture, blackcurrant-fish oil mixture, MCT (medium chain triglycerides)-soyabean oil mixture) on serum thromboxane B2 (TXB2) in four groups of rats. Plasma fatty acid composition showed differences related to dietary intakes. TXB2 levels were similar in all conditions except in the group receiving the mixture of olive-blackcurrant-fish oils which showed lower values.
Pregnolato
P
P
Istituto Clinico di Pediatria Preventiva e Neonatologia, Università di Bologna, Italy.
Maranesi
M
M
Bosi
I
I
Cocchi
M
M
Coccheri
S
S
Frascaro
M
M
Barzanti
V
V
D000818:Animals; D004281:Docosahexaenoic Acids / Q000378:metabolism / Q000494:pharmacology; D015118:Eicosapentaenoic Acid / Q000378:metabolism / Q000494:pharmacology; D005227:Fatty Acids / Q000032:analysis / Q000378:metabolism* / Q000494:pharmacology*; D005395:Fish Oils / Q000737:chemistry / Q000494:pharmacology; D005527:Food, Fortified; D005638:Fruit / Q000737:chemistry; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000378:metabolism / Q000494:pharmacology; D008055:Lipids / Q000097:blood / Q000737:chemistry; D019301:Oleic Acid / Q000378:metabolism / Q000494:pharmacology; D000069463:Olive Oil; D010938:Plant Oils / Q000737:chemistry / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D013024:Soybean Oil / Q000737:chemistry / Q000494:pharmacology; D013929:Thromboxane B2 / Q000096:biosynthesis / Q000097:blood*; D014280:Triglycerides / Q000737:chemistry / Q000494:pharmacology
D005227:Fatty Acids; D005395:Fish Oils; D008041:Linoleic Acids; D008055:Lipids; D000069463:Olive Oil; D010938:Plant Oils; D014280:Triglycerides; D004281:Docosahexaenoic Acids; D019301:Oleic Acid; D013929:Thromboxane B2; D013024:Soybean Oil; D019787:Linoleic Acid; D015118:Eicosapentaenoic Acid