title: The role of ultrasonography and inferior vena cava filter placement in high-risk trauma patients.
abstract: Undetected lower-extremity deep-vein thrombosis (LEDVT) in the trauma patient can lead to significant morbidity and mortality. The purpose of this study was to: 1) evaluate the role of ultrasonography in the early detection of LEDVT in high-risk trauma patients; 2) identify prognostic indicators that predict LEDVT; and 3) evaluate the efficacy of selected inferior vena cava (IVC) filter placement in the prevention of pulmonary emboli. From October 1993 through December 1994, all adult multiple-trauma patients admitted to the Trauma Service who required prolonged bed rest (>3 days) or sustained a lower-extremity, pelvic, or spinal fracture with paralysis were prospectively studied with serial physical examinations and lower-extremity venous ultrasounds within 72 hours of admission and then weekly until discharge. Two hundred twenty-eight patients were entered into the study. Thirty-nine patients (17%) developed ultrasound evidence of LEDVT; of these, only seven (18%) were evident on physical examination. This allowed 32 patients (82%) with unsuspected LEDVT to receive earlier definitive therapy. Multivariate logistic regression analysis of LEDVT with various predictors found age, hospital length of stay, and lower-extremity trauma to be significant predictors of LEDVT (P < 0.05). Twenty-nine patients (74%) had immediate IVC filter placement upon ultrasound identification of proximal LEDVT. None of these patients developed pulmonary emboli. Ten patients (26%) with a LEDVT were treated with systemic anticoagulation alone. One of these patients sustained a fatal pulmonary embolus. In a historic control group of 234 high-risk trauma patients admitted in the 14 months prior to implementing screening ultrasounds, six patients sustained pulmonary emboli (P < 0.05). Screening ultrasounds combined with selective placement of IVC filters play an important role in reducing the morbidity and mortality associated with LEDVT in high-risk trauma patients.
authors.affiliation: Department of Surgery, University of Tennessee College of Medicine, Chattanooga 37403, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: Headrick
authors.forename: D E
authors.initials: DE
authors.lastname: Barker
authors.forename: L M
authors.initials: LM
authors.lastname: Pate
authors.forename: K
authors.initials: K
authors.lastname: Horne
authors.forename: W L
authors.initials: WL
authors.lastname: Russell
authors.forename: R P
authors.initials: RP
authors.lastname: Burns
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D011379:Prognosis; D011446:Prospective Studies; D011655:Pulmonary Embolism / Q000209:etiology / Q000517:prevention & control*; D012307:Risk Factors; D013924:Thrombophlebitis / Q000150:complications* / Q000000981:diagnostic imaging* / Q000209:etiology; D016896:Treatment Outcome; D014463:Ultrasonography; D016306:Vena Cava Filters; D014947:Wounds and Injuries / Q000150:complications* / Q000000981:diagnostic imaging*