[Neonatal diabetes mellitus associated with an autoimmune disease].
BACKGROUND
Insulin-dependent diabetes mellitus can be associated to an auto-immune disease. A similar association may be seen in the neonate.


METHODS
A one-day-old boy was admitted for ketoacidosis due to diabetes mellitus. Investigation showed that he also suffered from an auto-immune enteropathy with several types of autoantibodies, particularly anti-enterocytes antibodies. Immunotherapy was ineffective. Multi-organ lesions developed subsequently, particularly a pulmonary disease responsible for the death at the age of 2 years.


CONCLUSIONS
Physiopathology of this association remains unclear and the report of further cases should help improve our knowledge.
Finel
E
E
Service de néonatologie-maternité et de réanimation pédiatrique, Brest, France.
Giroux
J D
JD
Metz
C
C
Robert
J J
JJ
Robert
O
O
Sadoun
E
E
Alix
D
D
de Parscau
L
L
D001327:Autoimmune Diseases / Q000150:complications*; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D007410:Intestinal Diseases / Q000276:immunology*; D008297:Male