Renal cortical necrosis in pregnancy-related acute renal failure.
Of 63 patients of obstetrical acute renal failure, 15 cases (23.8%) had biopsy proven bilateral renal cortical necrosis. Remaining 48 patients (76.2%) had acute tubular necrosis. Eight of 39 cases in early pregnancy had cortical necrosis (postabortum) and 7 of 24 patients in late pregnancy revealed cortical necrosis. Diffuse and patchy cortical necroses were seen in 12 and 3 patients respectively. The incidence of cortical necrosis was almost equal in both early as well as late pregnancies. The high incidence (20.5%) of cortical necrosis following septic abortion remains the interesting feature of the present study in contrast to very low incidence (1.5%) of cortical necrosis in postabortum group in developed countries. The death occurred in most patients (14 ie, 93.3%) of cortical necrosis because of uraemic complications and sepsis.
Prakash
J
J
Division of Nephrology, Institute of Medical Sciences, Banaras Hindu University, Varanasi.
Tripathi
K
K
Pandey
L K
LK
Gadela
S R
SR
Usha
D000031:Abortion, Septic / Q000150:complications; D058186:Acute Kidney Injury / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D007673:Kidney Cortex Necrosis / Q000150:complications* / Q000473:pathology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000473:pathology