title: The Women's Health Trial Feasibility Study in Minority Populations: design and baseline descriptions.
abstract: The Women's Health Trial: Feasibility Study in Minority Populations (WHT:FSMP), a randomized trial of 2208 women, was conducted to investigate three questions. First, can women from minority and low-socioeconomic-status populations be recruited in numbers sufficient to evaluate a dietary intervention designed to lower fat intake. Second, the efficacy of a low fat, increased fruit/vegetable/ grain product intervention for reducing fat consumption. Third, will participation in the intervention lower plasma cholesterol and estradiol levels relative to the controls. The baseline results showed that an adequate number of minority and low SES women could be recruited to test the study hypotheses. A diverse study population of postmenopausal women consuming a high fat diet was recruited: 28% of participants were Black, 16% were Hispanic, 11% had less than a high school level of education, and 15.5% had household incomes of < $15,000.
authors.affiliation: Emory School of Medicine, Atlanta, GA, USA.
authors.forename: D
authors.initials: D
authors.lastname: Bowen
authors.forename: C K
authors.initials: CK
authors.lastname: Clifford
authors.forename: R
authors.initials: R
authors.lastname: Coates
authors.forename: M
authors.initials: M
authors.lastname: Evans
authors.forename: Z
authors.initials: Z
authors.lastname: Feng
authors.forename: M
authors.initials: M
authors.lastname: Fouad
authors.forename: V
authors.initials: V
authors.lastname: George
authors.forename: T
authors.initials: T
authors.lastname: Gerace
authors.forename: J E
authors.initials: JE
authors.lastname: Grizzle
authors.forename: W D
authors.initials: WD
authors.lastname: Hall
authors.forename: M
authors.initials: M
authors.lastname: Hearn
authors.forename: M
authors.initials: M
authors.lastname: Henderson
authors.forename: M
authors.initials: M
authors.lastname: Kestin
authors.forename: A
authors.initials: A
authors.lastname: Kristal
authors.forename: E T
authors.initials: ET
authors.lastname: Leary
authors.forename: C E
authors.initials: CE
authors.lastname: Lewis
authors.forename: A
authors.initials: A
authors.lastname: Oberman
authors.forename: R
authors.initials: R
authors.lastname: Prentice
authors.forename: J
authors.initials: J
authors.lastname: Raczynski
authors.forename: B
authors.initials: B
authors.lastname: Toivola
authors.forename: N
authors.initials: N
authors.lastname: Urban
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D002791:Cholesterol, Dietary / Q000009:adverse effects; D004041:Dietary Fats / Q000009:adverse effects; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D008913:Minority Groups; D010349:Patient Compliance; D018579:Patient Selection; D016032:Randomized Controlled Trials as Topic; D015203:Reproducibility of Results; D012107:Research Design; D012307:Risk Factors; D012959:Socioeconomic Factors; D016387:Women's Health
chemical_list: D002791:Cholesterol, Dietary; D004041:Dietary Fats