Presenilin mutations in Alzheimer's disease: molecular models suggest a potential functional locus.
Murgolo
N J
NJ
Department of Structural Chemistry, Schering-Plough Research Institute, Kenilworth, NJ 07033, USA.
Brown
J E
JE
Bayne
M L
ML
Strader
C D
CD
D000544:Alzheimer Disease / Q000235:genetics*; D001665:Binding Sites; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics* / Q000502:physiology; D008958:Models, Molecular; D009154:Mutation; D053764:Presenilin-1; D053766:Presenilin-2
D008565:Membrane Proteins; C508853:PSEN1 protein, human; C508861:PSEN2 protein, human; D053764:Presenilin-1; D053766:Presenilin-2