Phospholipase C activation by VIP1 and VIP2 receptors expressed in COS 7 cells involves a pertussis toxin-sensitive mechanism.
MacKenzie
C J
CJ
MRC Brain Metabolism Unit, Edinburgh, Scotland. cmackenzie@srvl.bmu.mrc.ac.uk
Lutz
E M
EM
McCulloch
D A
DA
Mitchell
R
R
Harmar
A J
AJ
D000818:Animals; D019556:COS Cells; D002772:Cholera Toxin / Q000494:pharmacology; D004789:Enzyme Activation; D007295:Inositol Phosphates / Q000378:metabolism; D037342:Pertussis Toxin; D010739:Phospholipase D / Q000378:metabolism; D051381:Rats; D051236:Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; D011979:Receptors, Pituitary Hormone / Q000096:biosynthesis / Q000187:drug effects / Q000502:physiology*; D018005:Receptors, Vasoactive Intestinal Peptide / Q000096:biosynthesis / Q000187:drug effects / Q000502:physiology*; D051239:Receptors, Vasoactive Intestinal Peptide, Type II; D051238:Receptors, Vasoactive Intestinal Polypeptide, Type I; D011994:Recombinant Proteins / Q000187:drug effects / Q000378:metabolism; D014162:Transfection; D010738:Type C Phospholipases / Q000378:metabolism*; D014660:Vasoactive Intestinal Peptide / Q000494:pharmacology*; D010566:Virulence Factors, Bordetella / Q000494:pharmacology*
D007295:Inositol Phosphates; D051236:Receptors, Pituitary Adenylate Cyclase-Activating Polypeptide; D011979:Receptors, Pituitary Hormone; D018005:Receptors, Vasoactive Intestinal Peptide; D051239:Receptors, Vasoactive Intestinal Peptide, Type II; D051238:Receptors, Vasoactive Intestinal Polypeptide, Type I; D011994:Recombinant Proteins; D010566:Virulence Factors, Bordetella; D014660:Vasoactive Intestinal Peptide; D002772:Cholera Toxin; D037342:Pertussis Toxin; D010738:Type C Phospholipases; D010739:Phospholipase D