title: Radiation pneumonitis complicating mediastinal radiotherapy postpneumonectomy.
abstract: Radiation pneumonitis is a well-characterized clinicopathological syndrome. The severity of radiation-induced lung injury correlates, among other factors, with the extent of lung volume incorporated within the field of radiation. The present article describes the cases of two patients with radiation pneumonitis following pneumonectomy and mediastinal radiotherapy. Postpneumonectomy pulmonary-mediastinal shift of the remaining lung towards the operated side, with inclusion of lung parenchyma within the "mediastinal" radiation portals, resulted in a substantial (albeit clinically unsuspected) radiation pneumonitis. Chest computed tomography in the postpneumonectomy patient may be helpful to evaluate the degree of pulmonary-mediastinal shift and optimization of the radiotherapy field.
authors.affiliation: Division of Respiratory Medicine, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
authors.forename: T
authors.initials: T
authors.lastname: Shulimzon
authors.forename: S
authors.initials: S
authors.lastname: Apter
authors.forename: R
authors.initials: R
authors.lastname: Weitzen
authors.forename: A
authors.initials: A
authors.lastname: Yellin
authors.forename: H J
authors.initials: HJ
authors.lastname: Brenner
authors.forename: A
authors.initials: A
authors.lastname: Wollner
mesh_terms: D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D017564:Radiation Pneumonitis / Q000000981:diagnostic imaging* / Q000209:etiology; D011879:Radiotherapy Dosage; D014057:Tomography, X-Ray Computed