[An improved method of preparing protein and peptide probes in mass spectrometry with ionization of division fragments by californium-252 (TOF-PDMS)].
The addition of organic acids (picric, oxalic, citric, or tartaric) to peptide and protein samples was found to significantly increase the yield of their quasi-molecular ions (QMI) in time-of-flight 252Cf plasma desorption mass spectrometry. The yield of the ions depended on the pKa of the acid added.
Chivanov
V D
VD
Zubarev
R A
RA
Aksenov
S A
SA
Bordunova
O G
OG
Eremenko
V I
VI
Kabanets
V M
VM
Tatarinova
V I
VI
Mishnev
A K
AK
Kuraev
V V
VV
Knysh
A N
AN
Eremenko
I A
IA
D002142:Californium; D013058:Mass Spectrometry / Q000379:methods*; D015335:Molecular Probes; D010455:Peptides / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*
D015335:Molecular Probes; D010455:Peptides; D011506:Proteins; D002142:Californium