[Personal experience with the Mono type of insulin--clinical study].
A multicentric study was conducted in March to September 1995 to test the effectiveness and tolerance of a new insulin series. A total of 281 diabetics above 15 years of age were followed up, 144 men and 137 women, mean age 63 years with a duration of diabetes from 0.5 to 51 years, without serious organ complications and capable to recognise symptoms of hypoglycaemia. During the investigation a total of five examinations of the investigated parameters were made. The authors revealed a statistically insignificant decline of body weight, blood sugar level on fasting and HbA1c and a significant drop of the postprandial blood sugar level. The BP reading and urinary findings were unaltered. The authors found a significant drop of the daily insulin dose in MONO N, D and ID and an insignificant rise of the daily dose in MONO SD. The investigation provided evidence of a satisfactory effectiveness and tolerance of the new insulin series. In MONO N, D and ID there was also a decline in the total consumption.
Kalivoda
J
J
Perusicová
J
J
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001786:Blood Glucose / Q000032:analysis; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007328:Insulin / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged
D001786:Blood Glucose; D007328:Insulin