[The use of the antioxidant trimetazidine (Preductal) in the combined therapy of acute myocardial infarct].
86 patients with acute transmural and macrofocal myocardial infarction received combined treatment which included standard therapy (thrombolytic drugs, beta-blockers, APP inhibitors, nitrates, aspirin) and antioxidant trimetasidine. The addition of the latter was beneficial: the size of the myocardial lesion was limited, electrical instability of the heart attenuated, early dilatation of the left heart prevented.
Parkhomenko
A E
AE
Bryl'
Zh V
ZhV
Irkin
O I
OI
Shkliar
L V
LV
Antonov
A Ia
AIa
D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D006334:Heart Function Tests / Q000187:drug effects / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D012008:Recurrence; D013607:Tablets; D013997:Time Factors; D014292:Trimetazidine / Q000008:administration & dosage*
D000975:Antioxidants; D013607:Tablets; D014292:Trimetazidine