title: Evaluation of ureteropelvic junction obstruction (UPJO) by diuretic renography.
abstract: Of 52 cases with 56 affected renal units having symptoms and signs suggestive of Ureteropelvic Junction Obstruction (UPJO) evaluated by conventional (F + 15) diuretic renography where frusemide is given 15 minutes post-injection of radiopharmaceutical m99TC.DTPA.F + 15, twelve (21%) showed a good clearance (group A), 16 (28%) showed partial (group B) and 28 (50%) a poor clearance pattern (group C) indicating a definite obstruction. A high flow (F-15) diuretic renography where frusemide is given 15 minutes prior to the radiopharmaceutical m99TC.DTPA, was done in 23 cases with 27 affected renal units. Eleven renal units showed a good clearance (group A). Of these, 7 (64%) showed a persistent good clearance, 3 (27%) converted to poor clearance and 1 (9%) to partial clearance pattern. Of 8 renal units in group B, 5 (63%) converted to poor clearance and two (25%) to good clearance on F-15 and one remained unchanged. All renal units which presented as poor clearance (group C) on conventional (F + 15) diuretic renography remained unchanged on high flow (F-15) diuretic renography. In majority of cases conventional (F + 15) renography gave a reliable assessment of the upper tract drainage, however, since equivocal group was resolved by the F-15 and the intermittent obstruction group was definitely diagnosed, high flow (F-15) diuretic renography was more conclusive in assessment as compared to F + 15.
authors.affiliation: Sindh Institute of Urology and Transplantation, Dow Medical College and Civil Hospital, Karachi.
authors.forename: S
authors.initials: S
authors.lastname: Sultan
authors.forename: M
authors.initials: M
authors.lastname: Zaman
authors.forename: S
authors.initials: S
authors.lastname: Kamal
authors.forename: N
authors.initials: N
authors.lastname: Zafar
authors.forename: A
authors.initials: A
authors.lastname: Naqvi
authors.forename: A
authors.initials: A
authors.lastname: Rizvi
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D004232:Diuretics; D005260:Female; D005665:Furosemide; D006801:Humans; D007682:Kidney Pelvis / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D011866:Radioisotope Renography / Q000379:methods*; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D014517:Ureteral Obstruction / Q000175:diagnosis* / Q000000981:diagnostic imaging
chemical_list: D004232:Diuretics; D005665:Furosemide