title: [Optic nerve gliomas: a study of 11 cases].
abstract: Optic nerve gliomas may occur alone or as components of neurofibromatosis. They are rare tumors accounting for 2 to 5% of all intracranial tumors and 6% of the intra-orbitary neoplasms. The authors present 11 cases of optic nerve-glioma diagnosed in Curitiba in the last 25 years. Out of these 11 patients there were 10 women and only 1 man. The ages ranged from 3 to 25 years old, and 6 patients were under 15 years. In this series, 27.3% (n = 3) of the cases were associated with neurofibromatosis. Five patients had their tumors restricted to the optic nerve while the others had either extension to the optic chiasm, supra-selar region, frontal or temporal lobe. All the patients had pilocytic astrocytomas.
authors.affiliation: Seção de Microscopia Eletrônica e Neuropatologia, Universidade Federal do Paraná, Curitiba.
authors.forename: L F
authors.initials: LF
authors.lastname: Torres
authors.forename: B C
authors.initials: BC
authors.lastname: Medeiros
authors.forename: L
authors.initials: L
authors.lastname: Noronha
authors.forename: A
authors.initials: A
authors.lastname: Pedroso
authors.forename: R
authors.initials: R
authors.lastname: Ramina
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003390:Cranial Nerve Neoplasms / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D005910:Glioma / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D015994:Incidence; D008297:Male; D009901:Optic Nerve Diseases / Q000453:epidemiology* / Q000473:pathology; D015995:Prevalence