title: Chondrosarcoma of the skull base: CT, MR and pathological features.
abstract: We report on CT and MR image findings of a skull base chondrosarcoma. Chondroid mineralisation, a histological feature of chondrosarcoma, can be recognised on CT and is, together with the off-midline position of the tumour, the most characteristic finding. Differentiation is usually made by histological and immunocytochemical staining. Surgery, proton radiation therapy and stereotactic single high-dose irradiation have been used to treat patients with chondrosarcoma. It is worth mentioning that it was likely that the chondrosarcoma in our patient represented a malignant degeneration of an enchondroma that had been resected 30 years earlier.
authors.affiliation: Department of Diagnostic Radiology, Heilig Hart Ziekenhuis, Roeselare, Belgium.
authors.forename: G
authors.initials: G
authors.lastname: Maleux
authors.forename: P
authors.initials: P
authors.lastname: Demaerel
authors.forename: K
authors.initials: K
authors.lastname: Vanslambrouck
authors.forename: P
authors.initials: P
authors.lastname: Aerts
authors.forename: S
authors.initials: S
authors.lastname: Brijs
authors.forename: W
authors.initials: W
authors.lastname: Tanghe
mesh_terms: D000368:Aged; D002813:Chondrosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D019292:Skull Base Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed