title: Phylogenetic distribution of the global regulatory gene csrA among eubacteria.
abstract: The gene csrA encodes a unique kind of global regulator, CsrA, which modulates glycolysis, gluconeogenesis, glycogen biosynthesis and glycogen catabolism in Escherichia coli. Southern hybridization and nucleotide sequencing data have revealed apparent csrA homologs within several families of the alpha and gamma subdivisions of the proteobacteria (purple bacteria) and in the Gram-positive bacterium Bacillus subtilis. Thus, the CsrA regulatory system appears widely distributed among eubacteria.
authors.affiliation: Department of Microbiology, University of North Texas Health Science Center at Fort Worth 76107-2699, USA.
authors.forename: D
authors.initials: D
authors.lastname: White
authors.forename: M E
authors.initials: ME
authors.lastname: Hart
authors.forename: T
authors.initials: T
authors.lastname: Romeo
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry* / Q000235:genetics; D015139:Blotting, Southern; D003001:Cloning, Molecular; D029968:Escherichia coli Proteins; D005798:Genes, Bacterial / Q000235:genetics*; D008969:Molecular Sequence Data; D010802:Phylogeny; D016601:RNA-Binding Proteins / Q000737:chemistry* / Q000235:genetics; D012097:Repressor Proteins; D016415:Sequence Alignment; D017421:Sequence Analysis
chemical_list: D001426:Bacterial Proteins; C093587:CsrA protein, E coli; D029968:Escherichia coli Proteins; D016601:RNA-Binding Proteins; D012097:Repressor Proteins