[Malnutrition and HIV infection].
The wasting syndrome is well known in HIV infected patients. Predominant free fatty mass deletion is achieved. The weight loss results from decrease of food intake, from gut disorders due to HIV or opportunistic infections. Metabolic disorders are reported too. Breakdown of carbohydrates and proteins presents energy source. Raised free fatty acid turn over and hypertriglyceridemia are reported. Polyunsatured fatty acid level is raised inducing free radicals increase. Free radicals delete immune functions (apoptosis). Vitamin and trace element decrease worsen negative effects of free radicals.
Rabaud
C
C
Service de maladies infectieuses et tropicales, CHU de Nancy, hôpitaux de Brabois, Vandoeuvre-lès-Nancy, France.
Maignan
M
M
Amiel
C
C
Alfandari
S
S
May
T
T
Canton
P
P
D015658:HIV Infections / Q000150:complications* / Q000378:metabolism / Q000628:therapy; D006801:Humans; D009748:Nutrition Disorders / Q000209:etiology* / Q000378:metabolism / Q000628:therapy; D011379:Prognosis