[The factors determining survivorship in patients with colorectal carcinoma complicated by obstructive ileus of the large intestine].
A total of 232 patients with obturation ileus, caused by locally advanced colorectal carcinoma, are operated over a 12-year period (1979-1990). In 160 patients (68.97 per cent) the tumor is located in the colon, and in 72 (31.03 per cent)-in the rectum. The operative interventions performed are distributed as follows: 122 (52.58 per cent) radical, and 110 (47.42 per cent) palliative. There are 84 patients (36.03 per cent) in IV clinical stage. Postoperative lethality among those subjected to radical operation amounts to 25.41 per cent, with leading underlying causes-peritonitis (35.08 per cent) and serious ileus intoxication (21.05 per cent). The survival over 1, 3 and 5-year periods among those radically operated is 74.59, 48.37 and 34.06 per cent, respectively. Histologically differentiated adenocarcinoma is demonstrated in 69.38 per cent, undifferentiated-in 17.50 per cent, and mucinous adenocarcinoma-in 13.12 per cent. The factors with a high prognostic value include: stage of primary tumor development, lymph involvement, type of operative intervention and histological variant of the neoplasm.
Stoianov
Kh
Kh
Vŭlchev
D
D
Karashmalŭkov
A
A
Iuliianov
A
A
D000230:Adenocarcinoma / Q000150:complications / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D002031:Bulgaria / Q000453:epidemiology; D002277:Carcinoma / Q000150:complications / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000150:complications / Q000453:epidemiology* / Q000473:pathology / Q000601:surgery; D015179:Colorectal Neoplasms / Q000150:complications / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology / Q000401:mortality* / Q000473:pathology / Q000601:surgery; D007420:Intestine, Large / Q000601:surgery; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D010166:Palliative Care