title: Definitive radiation management for carcinoma of the glottic larynx.
abstract: Radiation therapy offers excellent cure rates and preservation of the larynx in the majority of early-stage glottic cancers. Outcome may vary because of patient-, tumor-, and treatment-related variables. Carefully selected advanced lesions may also be successfully managed with irradiation. Hyperfractionation and combined chemotherapy-radiotherapy protocols seem to be promising strategies for the improvement of the therapeutic ratio in treatment of patients with more advanced lesions.
authors.affiliation: Department of Radiation Oncology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina 27157, USA.
authors.forename: B D
authors.initials: BD
authors.lastname: Moose
authors.forename: K M
authors.initials: KM
authors.lastname: Greven
mesh_terms: D002277:Carcinoma / Q000188:drug therapy / Q000532:radiotherapy*; D002985:Clinical Protocols; D003131:Combined Modality Therapy; D005931:Glottis / Q000187:drug effects / Q000528:radiation effects*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D009367:Neoplasm Staging; D018579:Patient Selection; D011379:Prognosis; D011879:Radiotherapy Dosage; D015996:Survival Rate; D016896:Treatment Outcome