title: Value of CT scan in the diagnosis of meningitis.
abstract: OBJECTIVE
  To study the diagnostic test characteristics of computed tomography (CT scan) in differentiating tuberculous (TBM) and pyogenic (PM) meningitis.
  
  
  METHODS
  Prospective diagnostic test evaluation.
  
  
  METHODS
  Teaching hospital.
  
  
  METHODS
  Children beyond 1 month of age admitted with meningitis were enrolled prospectively and CT scan done. Results of CT scan were compared with predefined gold standards for the diagnosis of either TBM or PM.
  
  
  RESULTS
  CT scan was performed in 154 patients with meningitis. Of these 94 were TBM, 52 had PM and 8 were indeterminate and excluded from analysis. Basal enhancement, ventriculomegaly, tuberculoma and infarction were all significantly more common in the TBM group, while subdural collections were seen more in the PM group. The highest sensitivity (89.2%) and specificity (100%) for diagnosis of TBM were found for basal enhancement or tuberculoma or both.
  
  
  CONCLUSIONS
  CT scan can be used to effectively distinguish TBM and PM.
authors.affiliation: Department of Pediatrics, King George's Medical College, Lucknow.
authors.forename: R
authors.initials: R
authors.lastname: Kumar
authors.forename: N
authors.initials: N
authors.lastname: Kohli
authors.forename: H
authors.initials: H
authors.lastname: Thavnani
authors.forename: A
authors.initials: A
authors.lastname: Kumar
authors.forename: B
authors.initials: B
authors.lastname: Sharma
mesh_terms: D002544:Cerebral Infarction / Q000000981:diagnostic imaging; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006801:Humans; D007223:Infant; D008581:Meningitis / Q000000981:diagnostic imaging* / Q000382:microbiology; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed; D014375:Tuberculoma / Q000000981:diagnostic imaging; D014390:Tuberculosis, Meningeal / Q000000981:diagnostic imaging*