[The link between the prognostic factors in acute leukemia and patient age].
A total of 464 case records of those patients with acute leukosis 15 to 80 years old have been analysed. Age was found to have unfavourable potential for achieving complete remission as well as length of life of the patients. Other parameters of prognostic significance for the course of acute leukosis (cellularity of bone marrow, enlargement of peripheral lymph nodes, percentage of blast cells in haemogramme and myelogramme, thrombocytopenia) were not recognized to be directly age-associated. Age appeared to correlate significantly with infectious complications, pneumonia, as an immediate cause of death of the patients.
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D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000401:mortality*; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000401:mortality*; D011379:Prognosis; D012074:Remission Induction; D012189:Retrospective Studies