[Apropos of drug allergy].
Immuno-biological diagnosis of allergies lo medicines can be carried out using a Flow Cytometer and by activating cells such as basophils and lymphocytes with membrane markers. A description is given of two cases of patients allergic to a myorelaxant: Rocuronium, who showed a correlation between the clinical history, skin tests and a positive basophil activation test, when compared to six negative controls.
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D000707:Anaphylaxis / Q000139:chemically induced*; D000732:Androstanols / Q000009:adverse effects* / Q000276:immunology / Q000494:pharmacology; D015549:Basophil Degranulation Test; D001491:Basophils / Q000187:drug effects; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000209:etiology* / Q000276:immunology; D005434:Flow Cytometry; D006801:Humans; D003473:Neuromuscular Nondepolarizing Agents / Q000009:adverse effects* / Q000276:immunology / Q000494:pharmacology; D000077123:Rocuronium; D012882:Skin Tests
D000732:Androstanols; D003473:Neuromuscular Nondepolarizing Agents; D000077123:Rocuronium