Micronucleus test of erythrocytes and lymphocytes in the blood of the people living in the radiation pollution zone as a result of the accident at the Siberian chemical plant on April 6, 1993.
We have carried out analysis of the number of blood erythrocytes and lymphocytes with micronuclei in the inhabitants of four settlements located near the place of the accident which happened at the atomic power station of the Siberian chemical plant (Tomsk-7) on April 6, 1993. In all cases, the people examined showed a considerable increase in the number of cells with micronuclei as compared with the control. We observed the same people for 2 years and found a gradual decrease in the number of cells with micronuclei. This study shows that people born between 1963-1970 have a much higher level of cells with micronuclei, which we tend to see as a result of the radiation accident at the Siberian chemical plant in 1963. The data we have obtained allow us to conclude that penetration of radionuclides into the human organism in the prenatal and early postnatal periods can lead to the formation of stable clones of erythroid cells with micronuclei and a higher level of erythrocytes with micronuclei which can remain in the blood for a long time.
Ilyinskikh
N N
NN
Siberian Medical University, Russian Federation.
Eremich
A V
AV
Ivanchuk
I I
II
Ilyinskikh
E N
EN
D000328:Adult; D000396:Air Pollutants, Radioactive / Q000633:toxicity*; D002648:Child; D004912:Erythrocytes / Q000187:drug effects* / Q000528:radiation effects*; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects* / Q000528:radiation effects*; D015162:Micronucleus Tests; D044468:Native Hawaiian or Pacific Islander; D044469:Racial Groups; D012800:Siberia
D000396:Air Pollutants, Radioactive