Synthesis of a novel glycosaminoglycan pentasaccharide serine having an N-acetylgalactosamine residue alpha-linked to the core linkage tetrasaccharide.
A novel pentaosyl serine; GalNAcalpha(1--4)GlcAbeta(1--3)Galbeta(1--3)Galbeta  (1--4)Xylbeta(1--3)Ser (2), a putative intermediate of chondroitin sulfate and/or heparan sulfate biosynthesis, was synthesized.
Neumann
K W
KW
Institute of Physical and Chemical Research (RIKEN), Saitama, Japan.
Tamura
J
J
Ogawa
T
T
D000116:Acetylgalactosamine / Q000737:chemistry*; D002240:Carbohydrate Sequence; D002809:Chondroitin Sulfates / Q000737:chemistry / Q000378:metabolism; D006025:Glycosaminoglycans / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000138:chemical synthesis*; D012694:Serine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry*
D006025:Glycosaminoglycans; C104892:N-acetylgalactosaminyl-1-4-glucuronoyl-1-3-galactopyranosyl-1-3-galactopyranosyl-1-4-xylopyranosyl-1-3-serine; D009844:Oligosaccharides; D012694:Serine; D002809:Chondroitin Sulfates; D000116:Acetylgalactosamine