Reassignment of the 92-kDa type IV collagenase gene (CLG4B) to human chromosome 20.
The collagenase type IV B gene (CLG4B) was previously mapped to human chromosome 16 by hybridization of a cDNA probe to DNAs from a somatic cell hybrid panel. We have relocalized CLG4B to chromosome 20 based on three different lines of evidence: screening a somatic cell hybrid mapping panel, fluorescence in situ hybridization (FISH), and linkage analysis using a newly identified polymorphism.
Linn
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R
Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio 78284-7762, USA. Leach@uthscsa.edu
DuPont
B R
BR
Knight
C B
CB
Plaetke
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Leach
R J
RJ
D001483:Base Sequence; D002890:Chromosomes, Human, Pair 20 / Q000235:genetics*; D017364:Collagenases / Q000235:genetics*; D008040:Genetic Linkage; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction
D017364:Collagenases