title: Primary cardiac lymphoma.
abstract: Primary cardiac lymphoma is a rare entity. We report on the clinicopathological features of 2 patients with primary cardiac lymphomas: one involving the right atrium resulting in intractable right heart failure, and the other involving the pericardium with massive pericardial effusion. In the first patient, sternotomy and surgical biopsy of the tumor were performed to arrive at the diagnosis. In the second patient, CT thorax and transesophageal echocardiography helped to diagnose the pericardial tumor, and cytological examination of the pericardial fluid established the pathological diagnosis of lymphoma. Combination chemotherapy (COPP) was started in both patients. The first patient died on the first day of chemotherapy due to intractable heart failure, while the second attained a partial response to chemotherapy but died of progressive disease 8 weeks later. This is followed by a literature review of 21 patients with primary cardiac lymphoma. In conclusion, the prognosis of primary cardiac tumor remains poor.
authors.affiliation: Department of Medicine, Queen Mary Hospital, Hong Kong.
authors.forename: C S
authors.initials: CS
authors.lastname: Chim
authors.forename: A C
authors.initials: AC
authors.lastname: Chan
authors.forename: Y L
authors.initials: YL
authors.lastname: Kwong
authors.forename: R
authors.initials: R
authors.lastname: Liang
mesh_terms: D000368:Aged; D005260:Female; D006338:Heart Neoplasms / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis* / Q000473:pathology; D010496:Pericardium / Q000473:pathology; D014057:Tomography, X-Ray Computed