Dermatomal lichenoid chronic graft-vs-host disease following varicella-zoster infection despite absence of viral genome.
Localized cutaneous graft-versus-host disease (GVHD) following a dermatomal distribution or in a pattern of Blaschko's lines. Some authors have postulated that dermatomal GVHD is triggered by a varicella-zoster virus infection, although in reported cases, there was no history of a preceding herpes zoster. We describe a case of GVHD localized to the exact dermatome of a culture-proven varicella-zoster virus infection. PCR analysis failed to detect persistence of viral genome in the affected skin.
Baselga
E
E
Department of Dermatology, Medical College of Wisconsin, Milwaukee, USA.
Drolet
B A
BA
Segura
A D
AD
Leonardi
C L
CL
Esterly
N B
NB
D000293:Adolescent; D005260:Female; D006086:Graft vs Host Disease / Q000473:pathology* / Q000821:virology*; D006562:Herpes Zoster / Q000473:pathology*; D006801:Humans; D016133:Polymerase Chain Reaction; D012867:Skin / Q000473:pathology* / Q000821:virology; D017193:Skin Diseases, Viral / Q000473:pathology*