[Describing and interpreting systemic hypertension in heart transplantation with non-invasive arterial pressure monitoring].
This investigation was performed in 34 heart transplanted patients (HTP), 28 males and 6 females, mean age 49 +/- 13 years. The aim of the study was to detect hypertension in HTP by casual sphygmomanometry and non-invasive ambulatory blood pressure monitoring (ABPM). The evaluation of ABPM demonstrated that 71% out of the HTP was hypertensive because of some elevated blood pressure values scattered during the hours of the day and/or of the night. These hypertensives were found within the groups of normotensives as well as of hypertensives considered to be correctly treated. Fifty percent hypertensive HTP did not show the physiologic nocturnal decrease in blood pressure (non-dippers); 25% out of the non-dipper hypertensives showed absence of the blood pressure circadian rhythm, demonstrating that their hypertension was prevalently nocturnal and could not be detected by casual sphygmomanometry-The ABPM is recommended in clinical follow-up of HTP for a correct diagnosis of hypertension, which frequently complicates heart transplantation, and with the aim of avoiding hypertensive damage of the transplanted organ. The ABPM is useful for adjusting the antihypertensive therapy, in order to restore the blood pressure circadian rhythm.
Cugini
P
P
Istituto di Clinica Medica II, Università degli Studi, La Sapienza, Roma.
Chiera
A
A
Petrangeli
C M
CM
Capodaglio
P F
PF
Voci
P
P
Laurenti
A
A
Papalia
U
U
Marino
B
B
Scibilia
G
G
D000328:Adult; D001795:Blood Pressure Determination / Q000295:instrumentation; D018660:Blood Pressure Monitoring, Ambulatory; D004562:Electrocardiography; D005260:Female; D016027:Heart Transplantation / Q000502:physiology*; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged