Factors affecting recurrence in Crohn's disease. Results of a prospective audit.
It has been suggested that certain clinical and morphological features can modify the outcome of Crohn's disease, particularly regarding recurrence after surgery. A series of 233 patients was followed prospectively. They underwent a resectional surgical procedure for both primary and recurrent Crohn's disease during a fifteen-year period with a minimum follow-up of eighteen months. Possible risk factors for recurrence were studied. They included duration of disease before primary surgery, the type of clinical presentation at onset (whether "Perforating" or "Non-perforating"), the initial anatomical location, the presence of microscopic disease at the resection edges, the type of surgical procedure (anastomosis vs stoma), post-operative surgical complications and the age of the patient. The duration of the disease before the initial operation was the only significant factor related to the recurrence rate.
Poggioli
G
G
2nd Clinica Chirurgica, University of Bologna, Italy.
Laureti
S
S
Selleri
S
S
Brignola
C
C
Grazi
G L
GL
Stocchi
L
L
Marra
C
C
Magalotti
C
C
Grigioni
W F
WF
Cavallari
A
A
D000328:Adult; D003424:Crohn Disease / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008485:Medical Audit; D015999:Multivariate Analysis; D011446:Prospective Studies; D012008:Recurrence