title: Pure progressive clumsiness due to parietal atrophy in a young adult.
abstract: Progressive clumsiness developed in the right hand of a 33-year-old man, became bilateral and evolved very slowly for ten years. Another neurological deficit was restricted to a slight impairment of superficial sensations. Magnetic resonance imaging verified an atrophy of bilateral parietal lobes. The cerebral blood flow was markedly decreased in the atrophic area. Pure clumsiness of a very slowly progressive course due to parietal atrophy has never been reported in such a young adult. This clinical picture may suggest another variety of degenerative process.
authors.affiliation: Department of Neurology, Faculty of Medicine, Tokyo Medical and Dental University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Uchihara
authors.forename: A
authors.initials: A
authors.lastname: Inaba
authors.forename: T
authors.initials: T
authors.lastname: Yokota
authors.forename: T
authors.initials: T
authors.lastname: Furukawa
mesh_terms: D000328:Adult; D001072:Apraxias / Q000175:diagnosis* / Q000473:pathology; D001284:Atrophy; D001921:Brain / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation; D018450:Disease Progression; D006225:Hand; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009044:Motor Cortex / Q000473:pathology; D009410:Nerve Degeneration; D015609:Organotechnetium Compounds; D010091:Oximes; D010296:Parietal Lobe / Q000473:pathology*; D011877:Radionuclide Imaging; D019690:Technetium Tc 99m Exametazime
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime