[Biological activity of a carrier molecule-iron complex: probable mechanisms of intestinal absorption].
The physical-chemical properties of a new Iron-Protein complex, the so called "Iron Yeast" biotecnologically produced by Saccharomyces cerevisiae cell cultures, are reported. Using atomic absorption methods the amount of free iron in the complex has been evaluated, ascertaining that 99% of Iron is structurally bound to the protein matrix. Iron Yeast is a further, original contribution to the treatment of iron-deficiency anemias, showing a satisfactory clinical activity and a lower amount of undesired side effects in comparison with other Iron-Protein complexes.
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Centro di Biologia Molecolare, Milano.
D000747:Anemia, Hypochromic / Q000188:drug therapy; D000818:Animals; D006801:Humans; D007408:Intestinal Absorption / Q000187:drug effects / Q000502:physiology*; D007501:Iron / Q000737:chemistry* / Q000627:therapeutic use; D008667:Metalloproteins / Q000737:chemistry* / Q000627:therapeutic use; D013054:Spectrophotometry, Atomic
D008667:Metalloproteins; D007501:Iron