title: [The treatment of vibration-induced disease with calcium-channel blockers].
abstract: Effectiveness was studied of two drug preparations of calcium antagonists CAs group: cordaphene (30 mg) and diltiazeme (180 mg) in patients with vibration disease (VD) due to local vibration. CAs were shown to exert peripheral vasodilating, membrane-protecting and antioxidant effects. Cordaphene appeared to have a most pronounced CAs effect. We should advise its prescription preferably in those VD patients presenting with concomitant arterial hypertension.
authors.forename: I F
authors.initials: IF
authors.lastname: Kostiuk
authors.forename: V A
authors.initials: VA
authors.lastname: Kapustnik
mesh_terms: D000328:Adult; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D004110:Diltiazem / Q000627:therapeutic use*; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000097:blood / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D013607:Tablets; D014732:Vibration / Q000009:adverse effects*
chemical_list: D002121:Calcium Channel Blockers; D013607:Tablets; D004110:Diltiazem