Sister chromatid exchange frequency in inhabitants exposed to asbestos in Turkey.
Pleural mesothelioma, lung cancer, pleural calcification and fibrosis have been observed among inhabitants of the villages in Ivriz-Zanapa valley in Turkey. Earlier reports have stated that these endemic pathological conditions are caused by the inhalation of actinolite asbestos, a mineral commonly used indiscriminately to paint the walls and floors of houses. In the present study, 40 inhabitants in Yassikaya village in Ivriz-Zanapa valley and 20 controls were further investigated. The peripheral blood lymphocytes were cultured and harvested at 72 h for sister chromatid exchange (SCE) frequency. Inhabitants had a raised mean SCE rate compared with a control population.
Dönmez
H
H
Department of Medical Biology, Medical Faculty, Erciyes University, Kayseri, Turkey.
Ozkul
Y
Y
Uçak
R
R
D000328:Adult; D000368:Aged; D001194:Asbestos / Q000633:toxicity*; D002114:Calcinosis / Q000139:chemically induced; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000139:chemically induced; D008297:Male; D008654:Mesothelioma / Q000139:chemically induced; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000139:chemically induced; D011658:Pulmonary Fibrosis / Q000139:chemically induced; D012854:Sister Chromatid Exchange; D014421:Turkey
D001194:Asbestos