[Lipid disorders in non-insulin dependent diabetes--principles of treatment].
Hyperlipoproteinemia is one of the main coronary risk factors. Lipid metabolism disorders occur in about 40-60% of patients with NIDDM. Hyperlipidemia in diabetics is related to diabetes control, presence of diabetic nephropathy, diet, some drugs and genetic factors. Lipid metabolism disorders in NIDDM comprise qualitative changes--usually increase of serum triglyceride concentration and decrease of HDL--cholesterol, and qualitative changes of lipoprotein composition, glycation and oxidation. The first steps of hypolipemic therapy are good control of diabetes, reduction of overweight, hypolipidemic diet, and if a goal level is not achieved--farmacotherapy. Hypolipidemic treatment should be relevant in reduction of cardiovascular diseases in diabetic patients.
Idzior-Waluś
B
B
Katedry i Kliniki Chorób Metabolicznych, Collegium Medicum, Uniwersytetu Jagieliońskiego w Krakowie.
D008076:Cholesterol, HDL / Q000097:blood; D003327:Coronary Disease / Q000209:etiology / Q000517:prevention & control*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000378:metabolism / Q000628:therapy*; D006801:Humans; D006949:Hyperlipidemias / Q000150:complications / Q000378:metabolism / Q000628:therapy*; D006951:Hyperlipoproteinemias / Q000150:complications; D014280:Triglycerides / Q000097:blood
D008076:Cholesterol, HDL; D014280:Triglycerides