Cloning and mapping of a human novel cDNA (NHP2L1) that encodes a protein highly homologous to yeast nuclear protein NHP2.
We have isolated a novel human cDNA that encodes a protein highly homologous to NHP2, a nuclear protein of yeast, that is thought to have an essential physiological function for cell viability. The 1,493-bp cDNA sequence includes an open reading frame of 384 bp. This gene (NHP2L1) was expressed in all human tissues examined, and was localized to chromosome hand 12q24.3 by fluorescence in situ hybridization.
Saito
H
H
Department of Biochemistry, Cancer Institute, Tokyo, Japan.
Fujiwara
T
T
Shin
S
S
Okui
K
K
Nakamura
Y
Y
D000595:Amino Acid Sequence; D001483:Base Sequence; D002874:Chromosome Mapping; D018076:DNA, Complementary / Q000235:genetics*; D005656:Fungal Proteins / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008969:Molecular Sequence Data; D009687:Nuclear Proteins / Q000235:genetics*; D017411:Ribonucleoproteins, Small Nuclear; D012441:Saccharomyces cerevisiae; D029701:Saccharomyces cerevisiae Proteins
D018076:DNA, Complementary; D005656:Fungal Proteins; D009687:Nuclear Proteins; D017411:Ribonucleoproteins, Small Nuclear; D029701:Saccharomyces cerevisiae Proteins; C069628:NHP2 protein, S cerevisiae