title: Exophilin A, a new antibiotic from a marine microorganism Exophiala pisciphila.
abstract: Exophilin A, a new antibacterial compound, was discovered in the culture of the marine microorganism Exophiala pisciphila NI10102, which was isolated from a marine sponge Mycale adhaerens. The absolute chemical structure of exophilin A was elucidated as a trimer of (3R,5R)-3,5-dihydroxydecanoic acid by spectroscopic methods and analyses of a degradative product. Exophilin A showed antimicrobial activity against Gram-positive bacteria.
authors.affiliation: Central Research Laboratory, Nippon Suisan Kaisha, Ltd., Tokyo, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Doshida
authors.forename: H
authors.initials: H
authors.lastname: Hasegawa
authors.forename: H
authors.initials: H
authors.lastname: Onuki
authors.forename: N
authors.initials: N
authors.lastname: Shimidzu
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D003651:Decanoates / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D005285:Fermentation; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests
chemical_list: D000900:Anti-Bacterial Agents; D003651:Decanoates; C103160:exophilin A