title: The spectrum of chronic mature T-cell disorders: a report of four cases.
abstract: We describe four patients with a mature T-cell disorder. These four specific entities belong to a group formerly called "T-cell chronic lymphocytic leukaemia" (T-CLL). Nowadays we understand that these chronic T-cell lymphoproliferative disorders consist of four different entities. They stand out as well-described and separate disorders on the basis of their clinical, immunophenotypic and cytogenetic properties. Unfortunately, the majority of patients have a bad response to chemotherapy. The purine analogs may offer a better prognosis for some patients.
authors.affiliation: Department of Internal Medicine, Rode Kruis Hospital, Hague, Netherlands.
authors.forename: R E
authors.initials: RE
authors.lastname: Brouwer
authors.forename: S W
authors.initials: SW
authors.lastname: Kok
authors.forename: W A
authors.initials: WA
authors.lastname: van Deijk
authors.forename: P W
authors.initials: PW
authors.lastname: Wijermans
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D006801:Humans; D015458:Leukemia, T-Cell / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D008232:Lymphoproliferative Disorders / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D009182:Mycosis Fungoides / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D011379:Prognosis; D011687:Purines / Q000627:therapeutic use; D012751:Sezary Syndrome
chemical_list: D011687:Purines