[The prediction of individual radiosensitivity by the indices of blood chemiluminescence in intact animals].
The possibility of prediction of individual radiosensitivity by the chemiluminescence test is considered in this paper. Chemiluminescence is the phenomena which reflects a lot of biochemical processes connected indirectly with radiosensitivity. It has been established that dependence of the animal mortality on the value of the knmax/knmin ratio (kn coefficients of free-radical reaction rates) is of the parabolic shape. This agrees with available data that animals with extreme deviations of homoeostasis characteristics from average values are more susceptible to radiation than animals with characteristics close to average ones. Thus, the characteristics k1, k2 and k3 can be recommended as the determinants when predicting the radiation injury result.
Pavlenko
I O
IO
Istomina
H H
HH
Kataievs'kyĭ
Iu F
IuF
Chebotar'ov
Ue Iu
UIu
D000818:Animals; D001769:Blood / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D005609:Free Radicals / Q000097:blood / Q000528:radiation effects; D005720:Gamma Rays; D008163:Luminescent Measurements; D008297:Male; D010084:Oxidation-Reduction / Q000528:radiation effects; D011379:Prognosis; D011836:Radiation Tolerance / Q000502:physiology*; D051381:Rats
D005609:Free Radicals