Pseudomonas aeruginosa lipopolysaccharides and pathogenesis.
Pseudomonas aeruginosa lipopolysaccharide (LPS) plays a key role in pathogenesis. In acute infections, a smooth LPS protects the organism from complement-mediated killing and, during chronic lung infections, an altered rough LPS helps the organism evade host defense mechanisms.
Goldberg
J B
JB
Dept of Microbiology, University of Virginia Health Sciences Center, Charlottesville 22908, USA. jbg2b@virginia.edu
Pler
G B
GB
D003171:Complement Pathway, Classical / Q000276:immunology / Q000502:physiology; D006801:Humans; D007109:Immunity / Q000502:physiology; D008070:Lipopolysaccharides / Q000096:biosynthesis / Q000737:chemistry* / Q000276:immunology; D008171:Lung Diseases / Q000276:immunology / Q000382:microbiology; D011552:Pseudomonas Infections / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000737:chemistry* / Q000235:genetics / Q000472:pathogenicity*; D014612:Vaccines / Q000737:chemistry / Q000276:immunology
D008070:Lipopolysaccharides; D014612:Vaccines