title: Substituting traditional antipsychotics with risperidone for individuals with mental retardation.
abstract: The use of risperidone for 10 individuals with mental retardation and mental health disturbances was reported. A case study approach was employed to delineate the course of substitution of more traditional antipsychotic medications with risperidone. At the conclusion of the study, 6 of the 10 individuals had completed the substitution protocol. All participants evidenced improvement or resolution in side effects attributed to previous antipsychotic medication, with no worsening in psychiatric or behavioral status.
authors.affiliation: Elwyn Inc., Elwyn, PA 19063, USA.
authors.forename: E W
authors.initials: EW
authors.lastname: Simon
authors.forename: K M
authors.initials: KM
authors.lastname: Blubaugh
authors.forename: M
authors.initials: M
authors.lastname: Pippidis
mesh_terms: D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D015897:Comorbidity; D004305:Dose-Response Relationship, Drug; D004409:Dyskinesia, Drug-Induced / Q000517:prevention & control; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000188:drug therapy* / Q000523:psychology; D008297:Male; D001523:Mental Disorders / Q000188:drug therapy* / Q000523:psychology; D008875:Middle Aged; D018967:Risperidone / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D018967:Risperidone