title: Isolation of guaianoid pigments from the gorgonian Calicogorgia granulosa.
abstract: Three pigments of the guaiazulene class have been isolated from the gorgonian Calicogorgia granulosa. Structures of these compounds have been determined as guaiazulene, 2,2'- diguaiazulenylmethane, and a new compound, 2,2'-biguaiazulenyl, by combined chemical and spectroscopic methods. 2,2'-Biguaiazulenyl exhibited moderate antimicrobial activity.
authors.affiliation: Marine Natural Products Chemistry Laboratory, Korea Ocean Research & Development Institute, Seoul, Korea.
authors.forename: Y
authors.initials: Y
authors.lastname: Seo
authors.forename: J R
authors.initials: JR
authors.lastname: Rho
authors.forename: N
authors.initials: N
authors.lastname: Geum
authors.forename: J B
authors.initials: JB
authors.lastname: Yoon
authors.forename: J
authors.initials: J
authors.lastname: Shin
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000302:isolation & purification* / Q000494:pharmacology; D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology; D052176:Azulenes; D001412:Bacillus subtilis / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D003063:Cnidaria / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D012717:Sesquiterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D045789:Sesquiterpenes, Guaiane
chemical_list: C102489:2,2'-biguaiazulenyl; C102490:2,2'-diguaiazulenylmethane; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D052176:Azulenes; D012717:Sesquiterpenes; D045789:Sesquiterpenes, Guaiane; C004451:guaiazulene