title: Pharmacology of cancer chemotherapy in the older person.
abstract: With more widespread use of effective chemotherapy, more elderly patients are candidates for treatment with cytotoxic drugs. This article reviews and discusses the relevant age-related factors that may alter drug disposition and its relationship to pharmacokinetics effects and to pharmacodynamic effects in the elderly.
authors.affiliation: Department of Pharmacology and Medicine, University of Texas Health Science Center, San Antonio, Texas, USA.
authors.forename: S D
authors.initials: SD
authors.lastname: Baker
authors.forename: L B
authors.initials: LB
authors.lastname: Grochow
mesh_terms: D000368:Aged / Q000502:physiology*; D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D007408:Intestinal Absorption; D008657:Metabolic Clearance Rate; D014018:Tissue Distribution
chemical_list: D000970:Antineoplastic Agents