[The metabolism of [2-(14)C] glycine in rat tissues in vivo].
It is found that two hours after intraperitoneal injection of [2-(14)C] glycine to rats its higher amount (83.6%) is used in the protein synthesis and 16.4% is catabolized. The carbonic chain of the amino acid is used to the greater extent in the synthesis of lipids than in the oxidation and glucogenesis. Radioactivity of the proteins in the investigated organs and tissues of rats varies within L7-50.6 thou. DPM per 100 mg of wet tissue and decreases in a series: small intestine mucosa, kidneys, liver, stomach mucosa, heart, lungs, cardiac muscle, skin, skeletal muscle, adipose tissue, brain. Radioactivity of lipids is within the limits of 0.2-5.1 thou. DPM per 100 mg of wet tissue 11.7-81.6% of protein radioactivity) and decreases in a series: liver, adipose tissue, kidneys, lungs, cardiac muscle, stomach mucosa, skin, skeletal muscle, brain. The total radioactivity of glucose+glycogen varies within 0.05-0.34 thou. DPM per 100 mg of wet tissue (0.8-10.7% of protein radioactivity) and decreases is a series: kidneys, liver, brain, skeletal muscle.
Brodin
S V
SV
Ianovych
V H
VH
D000818:Animals; D002250:Carbon Radioisotopes; D005943:Gluconeogenesis; D005947:Glucose / Q000096:biosynthesis; D005998:Glycine / Q000008:administration & dosage / Q000378:metabolism*; D008055:Lipids / Q000096:biosynthesis; D008297:Male; D014176:Protein Biosynthesis; D051381:Rats
D002250:Carbon Radioisotopes; D008055:Lipids; D005947:Glucose; D005998:Glycine