title: EI-1511-3, -5 and EI-1625-2, novel interleukin-1 beta converting enzyme inhibitors produced by Streptomyces sp. E-1511 and E-1625. II. Structure determination.
abstract: The structures of three novel interleukin-1 beta converting enzyme inhibitors, EI-1511-3, -5 and EI-1625-2 were determined by spectroscopic methods. Their absolute configurations were also determined by analyses of the CD spectra of the inhibitors and their oxidation products with chromium trioxide.
authors.affiliation: Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Uosaki
authors.forename: T
authors.initials: T
authors.lastname: Agatsuma
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: Y
authors.initials: Y
authors.lastname: Saitoh
mesh_terms: D000577:Amides / Q000737:chemistry*; D003512:Cyclohexanones / Q000737:chemistry*; D004791:Enzyme Inhibitors / Q000737:chemistry*; D015843:Serpins; D013302:Streptomyces; D014764:Viral Proteins
chemical_list: D000577:Amides; D003512:Cyclohexanones; C103155:EI 1511-3; C103156:EI 1511-5; C103157:EI 1625-2; D004791:Enzyme Inhibitors; D015843:Serpins; D014764:Viral Proteins; C074641:interleukin-1beta-converting enzyme inhibitor