Comparison of [11C]methyl triflate and [11C]methyl iodide in the synthesis of PET radioligands such as [11C]beta-CIT and [11C]beta-CFT.
Någren
K
K
Radiopharmaceutical Chemistry Laboratory, Turku University Cyclotron, Turku, Finland.
Halldin
C
C
Müller
L
L
Swahn
C G
CG
Lehikoinen
P
P
D002247:Carbon Isotopes; D003042:Cocaine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D018765:Dopamine Uptake Inhibitors / Q000138:chemical synthesis*; D006847:Hydrocarbons, Iodinated / Q000737:chemistry*; D007202:Indicators and Reagents; D007553:Isotope Labeling; D008698:Mesylates / Q000737:chemistry*; D008745:Methylation; D011849:Radioactive Tracers; D014055:Tomography, Emission-Computed; D015899:Tomography, Emission-Computed, Single-Photon
D002247:Carbon Isotopes; D018765:Dopamine Uptake Inhibitors; D006847:Hydrocarbons, Iodinated; D007202:Indicators and Reagents; D008698:Mesylates; D011849:Radioactive Tracers; C078465:methyl triflate; C069723:2beta-carbomethoxy-3beta-(4-iodophenyl)tropane; C021279:(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester; C014055:methyl iodide; D003042:Cocaine