title: Triterpenoid saponins from Aster lingulatus.
abstract: Two new triterpenoid saponins named asterlingulatosides A and B were isolated from the whole plants of Aster lingulatus. Their structures were determined by spectroscopic data and chemical transformations to be 3-O-beta-D-glucopyranosyl-3 beta,16 alpha-dihydroxyolean-12-en-28-oic acid-28-O-alpha-L-O-arabinopyranoside and 3-O-beta-D-glucopyranosyl-3 beta,16 alpha-dihydroxyolean-12-en-28-oic acid-28-O-alpha-L-rhamnopyranosyl-(1-->2)-alpha-L-arabinopyranoside++ +. They showed inhibitory activity on DNA synthesis in human leukaemia HL-60 cells.
authors.affiliation: Department of Plant Science, Cook College, Rutgers, State University of New Jersey, New Brunswick 08903, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Shao
authors.forename: C T
authors.initials: CT
authors.lastname: Ho
authors.forename: C K
authors.initials: CK
authors.lastname: Chin
authors.forename: R T
authors.initials: RT
authors.lastname: Rosen
authors.forename: B
authors.initials: B
authors.lastname: Hu
authors.forename: G W
authors.initials: GW
authors.lastname: Qin
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry* / Q000633:toxicity; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D004261:DNA Replication / Q000187:drug effects; D018922:HL-60 Cells; D006801:Humans; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009828:Oleanolic Acid / Q000031:analogs & derivatives*; D010936:Plant Extracts; D010944:Plants; D012503:Saponins / Q000737:chemistry* / Q000302:isolation & purification / Q000633:toxicity; D013936:Thymidine / Q000378:metabolism; D014315:Triterpenes / Q000737:chemistry* / Q000633:toxicity
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D010936:Plant Extracts; D012503:Saponins; D014315:Triterpenes; C104099:asterlingulatoside A; C104100:asterlingulatoside B; D009828:Oleanolic Acid; D013936:Thymidine