EI-1511-3, -5 and EI-1625-2, novel interleukin-1 beta converting enzyme inhibitors produced by Streptomyces sp. E-1511 and E-1625. II. Structure determination.
The structures of three novel interleukin-1 beta converting enzyme inhibitors, EI-1511-3, -5 and EI-1625-2 were determined by spectroscopic methods. Their absolute configurations were also determined by analyses of the CD spectra of the inhibitors and their oxidation products with chromium trioxide.
Uosaki
Y
Y
Tokyo Research Laboratories, Kyowa Hakko Kogyo Co., Ltd., Japan.
Agatsuma
T
T
Tanaka
T
T
Saitoh
Y
Y
D000577:Amides / Q000737:chemistry*; D003512:Cyclohexanones / Q000737:chemistry*; D004791:Enzyme Inhibitors / Q000737:chemistry*; D015843:Serpins; D013302:Streptomyces; D014764:Viral Proteins
D000577:Amides; D003512:Cyclohexanones; C103155:EI 1511-3; C103156:EI 1511-5; C103157:EI 1625-2; D004791:Enzyme Inhibitors; D015843:Serpins; D014764:Viral Proteins; C074641:interleukin-1beta-converting enzyme inhibitor