title: Exercise-induced coronary spasm: comparison of treadmill and bicycle exercise in patients with vasospastic angina.
abstract: BACKGROUND
  We investigated whether exercise-induced coronary spasms are influenced by the different exercise modes.
  
  
  METHODS
  We compared ischaemic ECG responses in 67 patients with vasospastic angina who underwent both treadmill and bicycle ergometer exercise and also coronary angiography.
  
  
  RESULTS
  ECG ST-segment elevation was provoked more frequently during treadmill exercise than it was during bicycle exercise (19 versus 9%, P < 0.05). Of 45 patients without significant coronary stenosis (coronary artery luminal diameter narrowing < 75%), 19 patients manifested ST-segment depression during treadmill exercise, whereas only seven patients did during bicycle exercise (42 versus 16%, P < 0.01). All patients with ST-segment elevation or depression during bicycle ergometer exercise also had ST-segment changes during treadmill exercise. Although higher systemic blood pressure levels and lower heart rates were found during bicycle exercise compared with during treadmill exercise the pressure-rate products at peak exercise did not differ between the two exercise tests.
  
  
  CONCLUSIONS
  It seems that treadmill and bicycle exercise are different stressors in patients with vasospastic angina, and that coronary spasms are provoked more frequently during treadmill exercise than they are during bicycle exercise. The cause of this difference is not known, but it may be related in part to the difference in systemic haemodynamic or neurohumoral response.
authors.affiliation: First Department of Internal Medicine, Mie University, Tsu, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yamakado
authors.forename: A
authors.initials: A
authors.lastname: Kasai
authors.forename: T
authors.initials: T
authors.lastname: Masuda
authors.forename: Y
authors.initials: Y
authors.lastname: Futagami
authors.forename: A
authors.initials: A
authors.lastname: Kawasaki
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: T
authors.initials: T
authors.lastname: Nakano
mesh_terms: D000328:Adult; D000368:Aged; D000788:Angina Pectoris, Variant / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D001794:Blood Pressure; D017023:Coronary Angiography; D004562:Electrocardiography; D005080:Exercise Test / Q000009:adverse effects*; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D012146:Rest / Q000502:physiology; D012189:Retrospective Studies