The adverse effects of sectioning the posterior cruciate ligament in rabbits. Changes in the structural and morphological properties of the femur-anterior cruciate ligament-tibia complex.
This study examined the changes in the structural properties of the femur-anterior cruciate ligament-tibia complex (FATC) and the histologic changes of the anterior cruciate ligament (ACL) following sectioning of the posterior cruciate ligament (PCL) of 20 rabbits. The PCL in the right knee was sectioned through an arthrotomy. The left knee underwent arthrotomy only and was used as a control. The animals were killed 3 and 6 months postoperatively. The tensile properties of the FATCs were tested, and the ACLs were histologically examined using polarized light microscopy and transmission electron microscopy. There were significant decreases in the ultimate load following sectioning of the PCL, although there were no significant changes in the stiffness. There were no significant differences in either the crimp period or the crimp amplitude of the ACL following sectioning of the PCL. There were significant increases in the number of collagen fibrils per square micrometer, and significant decreases in the collagen fibril diameter and proportion of total collagen fibril area per square micrometer following sectioning of the PCL. These findings suggest that isolated PCL injury may cause pathological changes in the ACL and its insertion sites.
Murao
T
T
Department of Orthopaedic Surgery, Saiseikai-Hiroshima Hospital, Japan.
Ochi
M
M
Jitsuiki
J
J
Ikuta
D000818:Animals; D016118:Anterior Cruciate Ligament / Q000473:pathology*; D003094:Collagen / Q000032:analysis; D006651:Histocytochemistry; D007718:Knee Injuries / Q000473:pathology*; D008297:Male; D016119:Posterior Cruciate Ligament / Q000293:injuries*; D011817:Rabbits; D012421:Rupture; D013718:Tensile Strength
D003094:Collagen