Functional and pathophysiological models of the basal ganglia.
Because of new data, anatomical and functional models of the basal ganglia in normal and pathological conditions (e.g. Parkinson's and Huntington's diseases) have recently come under greater scrutiny. An update of these models is clearly timely, taking into consideration not only changes in neuronal discharge rates, but also changes in the patterning and synchronization of neuronal discharge, the role of extrastriatal dopamine, and expanded intrinsic and input/output connections of these nuclei.
Wichmann
T
T
Department of Neurology, Emory University School of Medicine, Suite 6000, Woodruff Memorial Research Building, 1639 Pierce Drive, Atlanta, Georgia 30322, USA. twichma@emory.edu
DeLong
M R
MR
D000818:Animals; D001479:Basal Ganglia / Q000033:anatomy & histology / Q000502:physiology* / Q000503:physiopathology*; D006801:Humans; D008959:Models, Neurological