title: Factors affecting recurrence in Crohn's disease. Results of a prospective audit.
abstract: It has been suggested that certain clinical and morphological features can modify the outcome of Crohn's disease, particularly regarding recurrence after surgery. A series of 233 patients was followed prospectively. They underwent a resectional surgical procedure for both primary and recurrent Crohn's disease during a fifteen-year period with a minimum follow-up of eighteen months. Possible risk factors for recurrence were studied. They included duration of disease before primary surgery, the type of clinical presentation at onset (whether "Perforating" or "Non-perforating"), the initial anatomical location, the presence of microscopic disease at the resection edges, the type of surgical procedure (anastomosis vs stoma), post-operative surgical complications and the age of the patient. The duration of the disease before the initial operation was the only significant factor related to the recurrence rate.
authors.affiliation: 2nd Clinica Chirurgica, University of Bologna, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Poggioli
authors.forename: S
authors.initials: S
authors.lastname: Laureti
authors.forename: S
authors.initials: S
authors.lastname: Selleri
authors.forename: C
authors.initials: C
authors.lastname: Brignola
authors.forename: G L
authors.initials: GL
authors.lastname: Grazi
authors.forename: L
authors.initials: L
authors.lastname: Stocchi
authors.forename: C
authors.initials: C
authors.lastname: Marra
authors.forename: C
authors.initials: C
authors.lastname: Magalotti
authors.forename: W F
authors.initials: WF
authors.lastname: Grigioni
authors.forename: A
authors.initials: A
authors.lastname: Cavallari
mesh_terms: D000328:Adult; D003424:Crohn Disease / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008485:Medical Audit; D015999:Multivariate Analysis; D011446:Prospective Studies; D012008:Recurrence