The effect of chitin synthesis inhibitors on the development of Brugia malayi in Aedes aegypti.
Two chitin synthesis inhibitors (CSIs) viz., triflumuron and hexaflumuron interfere++ with the development of Brugia malayi in Aedes aegypti (a black-eyed Liverpool strain). The development of B. malayi was slow in both the treated populations and the infection rate, infectivity rate and L3 load per mosquito decreased significantly (P < 0.001) in comparison with untreated controls. Hexaflumuron was found to be more inhibiting than triflumuron.
Mohapatra
R
R
Division of Medical Entomology and Parasitology, Regional Medical Research Centre (ICMR), Bhubaneswar, India.
Ranjit
M R
MR
Dash
A P
AP
D000330:Aedes / Q000469:parasitology*; D000818:Animals; D001549:Benzamides / Q000494:pharmacology; D017178:Brugia malayi / Q000187:drug effects* / Q000254:growth & development; D002686:Chitin / Q000037:antagonists & inhibitors* / Q000096:biosynthesis; D005260:Female; D007303:Insect Vectors / Q000469:parasitology*; D007306:Insecticides / Q000494:pharmacology*; D007605:Juvenile Hormones / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects / Q000254:growth & development; D010671:Phenylurea Compounds; D005466:Fluorocarbons
D001549:Benzamides; D002686:Chitin; D007306:Insecticides; D007605:Juvenile Hormones; D010671:Phenylurea Compounds; C023957:triflumuron; C058039:hexafluoron; D005466:Fluorocarbons