title: Tonsillectomy and inflammatory bowel disease location.
abstract: OBJECTIVE
  Epidemiological studies have found an increased frequency of childhood infections and tonsillectomies in patients with inflammatory bowel disease (IBD). The aim of our study was to test whether particular clinical patterns of IBD could be associated with previous tonsillectomy.
  
  
  METHODS
  Two hundred and twenty consecutive IBD patients (100 with Crohn's disease (CD) and 120 with ulcerative colitis (UC)) were prospectively assessed and classified into groups according to disease location. In those with a positive history of tonsillectomy, an ear, nose and throat (ENT) examination was carried out to confirm the diagnosis.
  
  
  RESULTS
  Eighty-two IBD patients (37%) underwent tonsillectomy in childhood: 47 out of 100 CD patients (47%), and 35 out of 120 UC patients (29%). Disease location in CD patients affected the ileum in 28, and 21 of them were tonsillectomized (tonsillectomy rate of 75%). Thirty-six patients had an ileocolonic location, and 14 of them had had a tonsillectomy (39%). With disease confined to the colon, only 9 out of 29 patients (31%) had undergone previous tonsillectomy. The higher prevalence of tonsillectomy in patients with CD ileitis was statistically significant (P = 0.0034). No significant differences between groups of UC patients according to the extent of the disease were found.
  
  
  CONCLUSIONS
  The ileum is the most prevalent location of disease in CD patients with previous tonsillectomy.
authors.affiliation: Hospital de la Princesa, Servicio de Aparato Digestivo, Universidad Autonoma de Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Maté-Jimenez
authors.forename: J A
authors.initials: JA
authors.lastname: Correa-Estañ
authors.forename: M
authors.initials: M
authors.lastname: Perez-Miranda
authors.forename: A
authors.initials: A
authors.lastname: Gomez-Cedenilla
authors.forename: J M
authors.initials: JM
authors.lastname: Pajares
authors.forename: R
authors.initials: R
authors.lastname: Moreno-Otero
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D003093:Colitis, Ulcerative / Q000453:epidemiology* / Q000473:pathology; D003106:Colon / Q000473:pathology; D003424:Crohn Disease / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007079:Ileitis / Q000453:epidemiology / Q000473:pathology; D007082:Ileum / Q000473:pathology; D008297:Male; D011446:Prospective Studies; D014068:Tonsillectomy / Q000009:adverse effects / Q000706:statistics & numerical data