[Blood flow lipid transport from viewpoint of protein biochemistry].
In accordance with the principles of protein biochemistry, apolipoprotein is the only protein which: 1) forms a protein-lipid complex (PLC) mainly from one class of lipids; 2) determines its functional role; 3) causes dyslipidemia in the genetic destruction of apoproteins or their quantitative ratio. Blood flow lipid transport is based on the functional specificity of their apoproteins; each apoprotein forms a functionally independent PLC; each PLC is formed from one class of lipids; each PLC has one protein-vector; each protein-vector interacts only with receptor. The basis of a united cycle functioning in lipid transport is the difference of primary apoprotein structure. Cholesterol performs an auxiliary function in triglyceride transport by providing circulation in the functional cycle. Lipid transport in blood flow is based, first, on the principles of protein biochemistry and, second, on those of lipidology.
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Cardiologic Scientific Center RAMN, Moscow.
D001053:Apolipoproteins / Q000097:blood; D001693:Biological Transport, Active; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood*; D008074:Lipoproteins / Q000097:blood*
D001053:Apolipoproteins; D008074:Lipoproteins