Pulmonary perfusion scintigraphy in the evaluation of the severity of bronchopulmonary dysplasia.
OBJECTIVE
The objectives of this study were to analyze the changes in pulmonary perfusion in bronchopulmonary dysplasia (BPD) and to assess the advantages of this method in evaluating the severity of BPD.


METHODS
The study group was made up of 10 children with BPD, matched with a control group of 12 children. The criteria for matching were birth weight, gestational age and need for ventilation for more than 3 days. Clinical and roentgenographic scoring systems were applied on the 21st day of life. At 6 months of corrected age, clinical evolutive severity was evaluated and a pulmonary perfusion scintigraphy using technetium-99 was performed in each child. The scintigraphic findings were classified in five categories ranging from normal to severely affected, depending on the degree and localization of perfusion abnormalities. Another score was obtained by assigning a value from 1 to 5 to each pulmonary lobe, depending on the concentration of the tracer.


RESULTS
The study of clinical, roentgenographic and evolutive scores always showed higher values in children with BPD, with good correlation between methods (P < 0.001). In the BPD group, abnormal lung perfusion patterns were more frequent and more severe (P < 0. 05), the lobe scoring was higher (P < 0.05), and a lower count rate was found (P < 0.01).


CONCLUSIONS
Pulmonary scintigraphy is a useful technique in evaluating the severity of BPD.
Soler
C
C
Neonatal Unit, Department of Pediatrics, Casa Maternitat Hospital, Clinical Hospital and Sant Joan de Déu Hospital, University of Barcelona, Barcelona, Spain.
Figueras
J
J
Roca
I
I
Pérez
J M
JM
Jiménez
R
R
D001997:Bronchopulmonary Dysplasia / Q000000981:diagnostic imaging*; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging