title: The effect of hexetidine spray on dental plaque following periodontal surgery.
abstract: The aim of the present study was to determine the effects of a 0.2% hexetidine spray, used as a supplement to regular oral hygiene measures, on dental plaque and gingival condition following periodontal surgery. This study was carried out on 38 patients who required 2 episodes of periodontal surgery. Examinations regarding dental plaque were performed at 0, 7, 14, 21 and 28 days, while the condition of the gingiva were examined at 0 and 28 days. Dental plaque was assessed by the Turesky modification of Quigley-Hein index; the gingival condition was evaluated using the gingival index of Löe-Silness and the papilla bleeding index. In a double-blind cross-over study of 28 days duration, significant reduction in plaque accumulation and an improvement in wound healing were demonstrated for the test spray compared to the placebo.
authors.affiliation: Department of Periodontology and Oral Medicine, Dental School, Faculty of Medicine, University of Novi Sad, Yugoslavia.
authors.forename: M
authors.initials: M
authors.lastname: Bokor
mesh_terms: D000328:Adult; D000336:Aerosols / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage* / Q000627:therapeutic use; D018592:Cross-Over Studies; D003773:Dental Plaque / Q000517:prevention & control*; D003774:Dental Plaque Index; D004311:Double-Blind Method; D006590:Hexetidine / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D010518:Periodontitis / Q000601:surgery*; D011182:Postoperative Care; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000336:Aerosols; D000891:Anti-Infective Agents, Local; D006590:Hexetidine