Dissecting how presinilins function--and malfunction.
Marx
J
J
D000544:Alzheimer Disease / Q000209:etiology* / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D016229:Amyloid beta-Peptides / Q000378:metabolism*; D016564:Amyloid beta-Protein Precursor / Q000737:chemistry / Q000378:metabolism*; D000818:Animals; D017209:Apoptosis; D001921:Brain / Q000473:pathology; D017173:Caenorhabditis elegans; D004721:Endoplasmic Reticulum / Q000378:metabolism; D006801:Humans; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism / Q000502:physiology*; D051379:Mice; D009154:Mutation; D009474:Neurons / Q000473:pathology; D010446:Peptide Fragments / Q000378:metabolism*; D053764:Presenilin-1; D053766:Presenilin-2; D017510:Protein Folding; D051880:Receptors, Notch; D015398:Signal Transduction
D016229:Amyloid beta-Peptides; D016564:Amyloid beta-Protein Precursor; D008565:Membrane Proteins; C508853:PSEN1 protein, human; C508861:PSEN2 protein, human; D010446:Peptide Fragments; D053764:Presenilin-1; D053766:Presenilin-2; D051880:Receptors, Notch; C075222:amyloid beta-protein (1-42)