[The selenium content of the body in experimental animals and its effect on the functional biochemical status of the liver in toxic injury].
Selenium content in organs and blood as well as the effect of diets with different selenium content on the functional and biochemical status of liver in toxic damage by tetrachloride carbon and ethyl alcohol was investigated on white male rats. Selenium content in the organism of experimental animals has been shown to undergo season fluctuations. Both tetrachloride carbon and ethyl alcohol have been shown to caise significant disturbances of functional and biochemical lever status at the background of selenium-deficient diet whereas selenium-enriched diet results in much less marked changes in the liver. These investigations provide grounds for considering selenium status in the organism with respect to preventing possible liver complications due to pathogenic factors.
Shman'ko
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D000818:Animals; D001823:Body Composition / Q000502:physiology*; D002252:Carbon Tetrachloride Poisoning / Q000503:physiopathology; D056486:Chemical and Drug Induced Liver Injury / Q000503:physiopathology*; D004032:Diet; D000431:Ethanol / Q000506:poisoning; D008099:Liver / Q000187:drug effects* / Q000503:physiopathology; D008297:Male; D051381:Rats; D012621:Seasons; D012643:Selenium / Q000008:administration & dosage / Q000737:chemistry* / Q000172:deficiency / Q000502:physiology
D000431:Ethanol; D012643:Selenium