[The effect of mercazolyl on the activity of the main hemostatic blood systems under the action of immobilization stress].
In the animal experiments (rabbits), a reaction was studied of lysosomal apparatus of the peripheral blood and haemostatic system neutrophilic leucocytes in response to exposure to immobilization stress under depression of thyroid system caused by administration of mercazolilum. Thyroid hormones were ascertained to play their part in regulation of functional activity of Hageman-dependent systems of blood via activation of lysosomal apparatus of neutrophilic leucocytes of the rabbits' blood.
Lunina
N V
NV
Honchar
O O
OO
D000135:Acid Phosphatase / Q000097:blood / Q000187:drug effects; D000818:Animals; D013956:Antithyroid Agents / Q000494:pharmacology*; D006487:Hemostasis / Q000187:drug effects*; D007958:Leukocyte Count / Q000187:drug effects; D008297:Male; D008713:Methimazole / Q000494:pharmacology*; D009504:Neutrophils / Q000187:drug effects / Q000201:enzymology; D011817:Rabbits; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000097:blood*; D013997:Time Factors
D013956:Antithyroid Agents; D008713:Methimazole; D000135:Acid Phosphatase