Deletion of the SRY region on the Y chromosome detected in bovine gonadal hypoplasia (XY female) by PCR.
In 6 sterile heifers which were female in appearance and in genital organs, all tissues derived from blood, skin, spleen and kidney had a single 60,XY type of metaphase plate. Although the SRY gene was detected by PCR in normal bull, it was not detected in normal cow or in 3 60,XY cases studied.
Kawakura
K
K
National Institute of Animal Industry, Tsukuba, Japan.
Miyake
Y I
YI
Murakami
R K
RK
Kondoh
S
S
Hirata
T I
TI
Kaneda
Y
Y
D000818:Animals; D002417:Cattle; D012734:Disorders of Sex Development / Q000235:genetics*; D005260:Female; D016133:Polymerase Chain Reaction; D014998:Y Chromosome