Expression of the PIP/GCDFP-15 gene and survival in breast cancer.
Expression of the PIP/GCDFP-15 gene was determined by measuring PIP/GCDFP-15-mRNA in breast carcinomas of 91 patients. The patients were followed-up for an average of 47 months after initial diagnosis and treatment of the disease. There were no deaths in the group of 14 patients with tumours of high PIP/GCDFP-15-mRNA levels, while 16 of 77 patients of the group with low PIP/GCDFP-15-mRNA tumour levels died. A similar advantage for high PIP/GCDFP-mRNA expression was observed with regard to disease free survival.
Hähnel
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Department of Pathology, University of Western Australia, Queen Elizabeth II Medical Centre, Nedland, Australia.
Hähnel
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D001426:Bacterial Proteins / Q000235:genetics*; D001943:Breast Neoplasms / Q000235:genetics* / Q000378:metabolism / Q000401:mortality*; D002277:Carcinoma / Q000235:genetics* / Q000378:metabolism / Q000401:mortality*; D005260:Female; D015870:Gene Expression; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008565:Membrane Proteins; D009364:Neoplasm Recurrence, Local; D012333:RNA, Messenger / Q000378:metabolism; D016019:Survival Analysis
D001426:Bacterial Proteins; D008565:Membrane Proteins; D012333:RNA, Messenger; C082934:phage infection protein, Lactococcus lactis