title: Effect of ochratoxin A on Salmonella typhimurium-challenged layer chickens.
abstract: Eleven-day-old chickens received 10(8) colony-forming units Salmonella typhimurium orally for 2 consecutive days. The next day, the 13-day-old chickens were given a high dose of ochratoxin A (3 mg/kg) orally. The number of S. typhimurium in both the duodenal and cecal contents of chickens administered with high doses of ochratoxin A increased significantly when compared with control birds. Ochratoxin A was shown to be one of numerous factors that affect the susceptibility of chickens to salmonellae colonization.
authors.affiliation: Department of Veterinary Medicine, College of Agriculture, Osaka Prefecture University, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Fukata
authors.forename: K
authors.initials: K
authors.lastname: Sasai
authors.forename: E
authors.initials: E
authors.lastname: Baba
authors.forename: A
authors.initials: A
authors.lastname: Arakawa
mesh_terms: D000284:Administration, Oral; D000818:Animals; D002432:Cecum / Q000382:microbiology; D002645:Chickens; D004305:Dose-Response Relationship, Drug; D004386:Duodenum / Q000382:microbiology; D009183:Mycotoxins / Q000008:administration & dosage / Q000627:therapeutic use*; D009793:Ochratoxins / Q000008:administration & dosage / Q000627:therapeutic use*; D011201:Poultry Diseases / Q000188:drug therapy*; D012481:Salmonella Infections, Animal / Q000188:drug therapy*; D012486:Salmonella typhimurium / Q000302:isolation & purification* / Q000502:physiology
chemical_list: D009183:Mycotoxins; D009793:Ochratoxins; C025589:ochratoxin A