Effect of aluminum on superoxide dismutase, catalase and lipid peroxidation of rat liver.
Results of the present study suggest that aluminum treatment to rats resulted in elevation of microsomal lipid peroxidation along with inhibition of catalase activity in the liver. Aluminum treatment to rats has no significant effect on rat liver superoxide dismutase activity. A 25% inhibition in catalase activity was observed when liver supernatant was incubated with A1C13 at 5 x 10(-3) M concentration and above.
Chainy
G B
GB
Department of Zoology, Utkal University, Bhubaneswar, India.
Samanta
L
L
Rout
N B
NB
D000535:Aluminum / Q000494:pharmacology*; D000818:Animals; D002374:Catalase / Q000378:metabolism*; D005260:Female; D015227:Lipid Peroxidation / Q000187:drug effects*; D008099:Liver / Q000187:drug effects* / Q000201:enzymology / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013482:Superoxide Dismutase / Q000378:metabolism*
D000535:Aluminum; D002374:Catalase; D013482:Superoxide Dismutase