Identification of the bacteriophage T5 dUTPase by protein sequence comparisons.
It is shown by protein sequence comparisons that a 148 amino acid open reading frame (ORF 148) located at 67% of the bacteriophage T5 genome encodes a protein with strong similarity to known dUTPases. This protein contains five characteristic amino acid sequence motifs that are common to the dUTPase gene family. A similarity in size and high degree of sequence identity strongly suggest that the protein encoded by the ORF 148 of bacteriophage T5 is dUTPase.
Kaliman
A V
AV
Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Russia. Kaliman@ibpm.serpukhov.su
D000595:Amino Acid Sequence; D006801:Humans; D008969:Molecular Sequence Data; D011755:Pyrophosphatases / Q000235:genetics*; D017386:Sequence Homology, Amino Acid; D013604:T-Phages / Q000201:enzymology* / Q000235:genetics
D011755:Pyrophosphatases; C020020:dUTP pyrophosphatase