title: Granulosa cell tumor of the ovary.
abstract: From January 1984 to December 1994, 36 women with granulosa cell tumors of the ovary were treated at Maharaj Nakorn Chiang Mai Hospital, which accounted for 5.8 per cent of all 620 ovarian malignancies treated at this institute. Twenty patients were in stage I, 2 in stage II, 11 in stage III and the remaining 3 cases were in stage IV. Most patients had unilateral ovarian involvement while 6 (16.7%) had bilateral involvement. The diameter of the tumor ranged from 4 to 30 cm with the median of 14 cm. Treatment consisted of hysterectomy and bilateral salpingo-oophorectomy followed by chemotherapy in most cases. To date 10 patients have no evidence of disease while 9 died of the disease, others were lost to follow-up. The 5-year survival was 94 per cent in the early stages compared to 25 per cent in advanced stages. The overall survival rate was 62.7 per cent for all stages.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Thailand.
authors.forename: S
authors.initials: S
authors.lastname: Maleemonkol
authors.forename: V
authors.initials: V
authors.lastname: Chareonium
authors.forename: P
authors.initials: P
authors.lastname: Isariyodom
authors.forename: S
authors.initials: S
authors.lastname: Faichamnan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006106:Granulosa Cell Tumor / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy; D012189:Retrospective Studies; D015996:Survival Rate