title: Localization of lesion in denial of hemiplegia after acute stroke.
abstract: OBJECTIVE
  Previous studies of lesion localization in dental of hemiplegia have often been confounded by factors such as the cerebral etiology, which aspects of the disorder are denied, and whether delusions are present. Our investigation focuses on denial of hemiplegia, without concomitant delusions, after cerebrovascular accident (CVA).
  
  
  METHODS
  The CT scans of 30 patients with denial of hemiplegia after acute stroke were compared with those from 10 CVA patients with hemiplegia and visuospatial neglect but no denial. Lesion sites were detailed using the templates of Damasio and Damasio and, for the deep structures, those of Talairach and Tournoux.
  
  
  RESULTS
  Analysis of the CT scans demonstrated that 26 of 30 denial patients had unilateral right-sided lesions and that this group showed a significantly higher incidence of lesions in deep white matter and the basal ganglia.
  
  
  CONCLUSIONS
  The results are discussed in relation to recent ideas regarding the role of the basal ganglia and subcortical circuits in movement and executive function.
authors.affiliation: Department of Neurology, North Staffordshire Royal Infirmary, Stoke-on-Trent, UK.
authors.forename: S
authors.initials: S
authors.lastname: Ellis
authors.forename: M
authors.initials: M
authors.lastname: Small
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000000981:diagnostic imaging*; D002543:Cerebral Hemorrhage / Q000503:physiopathology; D002544:Cerebral Infarction / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D003717:Denial, Psychological; D005260:Female; D007839:Functional Laterality; D006429:Hemiplegia / Q000209:etiology / Q000503:physiopathology* / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010465:Perception; D014057:Tomography, X-Ray Computed