title: Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. CI-1011: an acyl sulfamate with unique cholesterol-lowering activity in animals fed noncholesterol-supplemented diets.
authors.affiliation: Department of Medicinal Chemistry, Radiochemistry, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, Ann Arbor, Michigan 48105, USA.
authors.forename: H T
authors.initials: HT
authors.lastname: Lee
authors.forename: D R
authors.initials: DR
authors.lastname: Sliskovic
authors.forename: J A
authors.initials: JA
authors.lastname: Picard
authors.forename: B D
authors.initials: BD
authors.lastname: Roth
authors.forename: W
authors.initials: W
authors.lastname: Wierenga
authors.forename: J L
authors.initials: JL
authors.lastname: Hicks
authors.forename: R F
authors.initials: RF
authors.lastname: Bousley
authors.forename: K L
authors.initials: KL
authors.lastname: Hamelehle
authors.forename: R
authors.initials: R
authors.lastname: Homan
authors.forename: C
authors.initials: C
authors.lastname: Speyer
authors.forename: R L
authors.initials: RL
authors.lastname: Stanfield
authors.forename: B R
authors.initials: BR
authors.lastname: Krause
mesh_terms: D000081:Acetamides; D000085:Acetates; D000818:Animals; D000924:Anticholesteremic Agents / Q000737:chemistry / Q000494:pharmacology*; D004032:Diet; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D011817:Rabbits; D051381:Rats; D002785:Sterol O-Acyltransferase / Q000037:antagonists & inhibitors*; D013449:Sulfonamides; D013451:Sulfonic Acids / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000081:Acetamides; D000085:Acetates; D000924:Anticholesteremic Agents; D004791:Enzyme Inhibitors; D013449:Sulfonamides; D013451:Sulfonic Acids; C423185:avasimibe; D002785:Sterol O-Acyltransferase