[Clinical study of home hepatic arterial infusion chemotherapy for liver metastasis from colorectal cancer].
The clinical response and QOL were examined with 16 outpatients treated with home hepatic arterial infusion chemotherapy for liver metastasis from colorectal cancer. Fluorouracil 1,000 mg/body/week was administered by 5-hour intra-arterial infusion with a portable disposable pump. Six out of 8 who replied to a questionnaire survey led a their usual life during the treatment, and the average hospitalization period was only 7 days (including mortal cases). The clinical response was evaluated with 13 patients; 3 prophylactic treatment cases were excluded from the original 16 cases. The number of partial responses and no change were 3 and 7, respectively, and the overall response rate was 23.1%. These studies suggest that home hepatic arterial infusion chemotherapy is beneficial for patients with liver metastasis by improving their QOL.
Sato
K
K
Dept. of Surgery, Fuji Municipal Hospital.
Takahashi
T
T
Ashikaga
K
K
Hanyu
N
N
Aoki
T
T
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage*; D015179:Colorectal Neoplasms / Q000473:pathology*; D004209:Disposable Equipment; D005472:Fluorouracil / Q000008:administration & dosage*; D006499:Hepatic Artery; D018718:Home Infusion Therapy; D006801:Humans; D015918:Infusion Pumps, Implantable; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008875:Middle Aged; D011788:Quality of Life
D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil