[The reaction of the sympathoadrenal system to an acute peroral salt load in young persons with arterial hypertension].
73 young persons 15 to 30 years old with normal and elevated arterial pressure were studied for excretion of epinephrine, norepinephrine and dophamine during 3 and 24 hours after acute peroral salt loading (0.22 g/l kg of body mass). The study was made with special reference to the family prevalence of hypertensive disease. Healthy subjects demonstrated an increased excretion of dopamine and decreased excretion of norepinephrine after the test. Those persons with arterial hypertension showed disordered reaction of the sympathoadrenal system to the salt loading. Functional mechanisms of hereditary predisposition to this medical condition involve a decreased excretion of dophamine in the first three hours and increased excretion of epinephrine within the 24 hours after the test.
Berezniakov
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D000284:Administration, Oral; D000293:Adolescent; D000311:Adrenal Glands / Q000187:drug effects* / Q000503:physiopathology; D000328:Adult; D002395:Catecholamines / Q000652:urine; D004198:Disease Susceptibility; D006801:Humans; D006973:Hypertension / Q000235:genetics / Q000503:physiopathology* / Q000652:urine; D009318:Natriuresis / Q000187:drug effects; D017673:Sodium Chloride, Dietary / Q000008:administration & dosage*; D013564:Sympathetic Nervous System / Q000187:drug effects* / Q000503:physiopathology; D013997:Time Factors
D002395:Catecholamines; D017673:Sodium Chloride, Dietary