title: Surgical treatment of infected necrosis.
abstract: Over the years, experience has shown that the cornerstone for improved survival in patients with infected pancreatic necrosis is an early, precise diagnosis followed by adequate drainage combined with modern intensive care management. In experienced hands, this goal can be achieved with different surgical approaches, provided that all septic collections are thoroughly removed and that reexploration is performed promptly if there is evidence of ongoing sepsis. If there is any concept preferable, and under what conditions, future large-scale randomized trials with precise and comparable patient stratification will have to demonstrate it.
authors.affiliation: Department of General Surgery, University of Ulm, Steinhövelstrasse 9, 89075 Ulm, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Rau
authors.forename: W
authors.initials: W
authors.lastname: Uhl
authors.forename: M W
authors.initials: MW
authors.lastname: Buchler
authors.forename: H G
authors.initials: HG
authors.lastname: Beger
mesh_terms: D003646:Debridement; D004322:Drainage; D016905:Gram-Negative Bacterial Infections; D006801:Humans; D019283:Pancreatitis, Acute Necrotizing / Q000382:microbiology / Q000601:surgery*; D013514:Surgical Procedures, Operative / Q000379:methods