title: Otomycosis--a clinico-mycological study and efficacy of mercurochrome in its treatment.
abstract: A total of 110 patients of symptomatic otomycosis was investigated, prospectively. Aural swabs were collected on 1st, 7th and 14th day and examined by direct microscopy and culture for fungi. Of these, 80 patients found to be having pure fungal infection, were taken up for mycological and therapeutic study. Fungi belonging to genus Aspergillus were isolated in 76 (95.0%) patients of which Aspergillus niger was the commonest isolate in 46 (57.5%), followed by A. flavus in 27 (33.7%), A. fumigatus in 3 (3.7%), Candida species in 3 (3.7%) and Mucor in 1 (1.2%). The patients were of all age groups but majority were between 21 and 30 years and the male-female ratio was equal. Of the total of 40 male patients, twenty-one were Sikhs using turban. Before developing the symptoms, forty five patients used oil, mixture of oil and garlic juice, antibiotics, steroids, antiseptics or wax solvent as ear drops. Only two patients were diabetic. No patient had fungal infection elsewhere in the body. The patients were called for regular follow-up for three weeks. In forty cases mercurochrome was applied as the antifungal agent after cleaning the external auditory canal, in twenty-three clotrimazole and in rest of the seventeen patients miconazole was used. On 7th day, only 11 (13.7%) patients grew different fungi in culture. They became symptom-free on 14th day and no fungal material could be seen on otoscopy, direct microscopy or culture. Mercurochrome was found to be most effective in these patients.
authors.affiliation: Department of Microbiology, Government Medical College Hospital, Chandigarh, India.
authors.forename: J
authors.initials: J
authors.lastname: Chander
authors.forename: S
authors.initials: S
authors.lastname: Maini
authors.forename: S
authors.initials: S
authors.lastname: Subrahmanyan
authors.forename: A
authors.initials: A
authors.lastname: Handa
mesh_terms: D000328:Adult; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use; D001230:Aspergillus / Q000302:isolation & purification; D002175:Candida / Q000302:isolation & purification; D003022:Clotrimazole / Q000627:therapeutic use; D048909:Diabetes Complications; D004427:Ear Diseases / Q000188:drug therapy* / Q000382:microbiology*; D005260:Female; D006801:Humans; D008297:Male; D008622:Merbromin / Q000627:therapeutic use*; D008825:Miconazole / Q000627:therapeutic use; D009089:Mucor / Q000302:isolation & purification; D009181:Mycoses / Q000188:drug therapy* / Q000382:microbiology*; D011446:Prospective Studies
chemical_list: D000891:Anti-Infective Agents, Local; D000935:Antifungal Agents; D008825:Miconazole; D003022:Clotrimazole; D008622:Merbromin