title: Nasopharyngeal Castleman's disease.
abstract: A 19-year-old male was admitted to our clinic because of nasal obstruction and intermittent postnasal drip of 3 to 4 years' duration. Physical examination revealed a wide-based, smooth-surfaced nasopharyngeal tumor which was suspected to be a nasopharyngeal angiofibroma after examination of computed tomographic scans and an angiogram. However, after the tumor was removed by surgical excision via a transpalatal approach, the pathologic examination revealed Castleman's disease of the hyaline-vascular type. There was neither evidence of recurrence nor nasal problems at 4 years' follow-up. To our knowledge, Castleman's disease, or angiofollicular lymph node hyperplasia, may present as a local or generalized tumor-like condition, usually in the chest or abdomen, and may involve both the lymph nodes and non-nodal tissues. A review of previous articles reveals that there has not been any report of Castleman's disease found in the nasopharynx. This rare disorder is presented and discussed.
authors.affiliation: Department of Otolaryngology, Chang Gung Memorial Hospital, Taipei, Taiwan, ROC.
authors.forename: M H
authors.initials: MH
authors.lastname: Tsai
authors.forename: H H
authors.initials: HH
authors.lastname: Pai
authors.forename: P T
authors.initials: PT
authors.lastname: Yen
authors.forename: T S
authors.initials: TS
authors.lastname: Huang
authors.forename: Y S
authors.initials: YS
authors.lastname: Ho
mesh_terms: D000328:Adult; D005871:Castleman Disease / Q000175:diagnosis / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D009302:Nasopharyngeal Diseases / Q000175:diagnosis / Q000473:pathology*; D014057:Tomography, X-Ray Computed