O-demethylation of 7,7'-epoxylignans by Aspergillus niger.
Biotransformation of the 7,7'-epoxylignans, (+)-veraguensin, (+)-galbelgin and galgravin by Aspergillus niger has been investigated. These lignans were converted to their corresponding 4,4'-O-demethyl derivatives, (+)-verrucosin, (+)-fragransin A2 and nectandrin B.
Kasahara
H
H
Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Osaka, Japan.
Miyazawa
M
M
Kameoka
H
H
D001234:Aspergillus niger / Q000378:metabolism*; D001711:Biotransformation; D005663:Furans / Q000737:chemistry / Q000493:pharmacokinetics*; D008401:Gas Chromatography-Mass Spectrometry; D017705:Lignans; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation
D005663:Furans; D017705:Lignans; C084077:galgravin