[Infiltration of the testes in acute lymphoblastic leukemia in childhood--personal experience].
According to various literature data testicular leukemic infiltration occurs in 5-40%, while the mean time for testicular recurrence is 36 months. Hematologic recurrence usually occurs in the interval from 1-6 months. Although testicular leukemic infiltration clinically occurs as an isolated recurrence of leukemia, it usually presents only a clearly marked spot in the general recurrence of the disease. It is a painless enlargement of one or both testes. The diagnosis is made ultrasonographically and by histopathologic examination of the biopsied testicle tissue. This paper deals with 4 patients with acute lymphoblastic leukemia and testicular recurrence. In 2 patients the testicular recurrence occurred as a part of the general recurrence of the disease, while in the other 2 at the time of testicular recurrence diagnosis, the bone marrow was regular. All 4 patients were treated with combined radiotherapy and chemotherapy, in 3 cases successfully.
Konstantinidis
N
N
Institut za zdravstvenu zastitu dece i omladine, Medicinski fakultet, Novi Sad.
Gebauer
E
E
Krstić
R
R
Konstantinidis
G
G
D002648:Child; D002675:Child, Preschool; D006801:Humans; D017254:Leukemic Infiltration; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology*; D013737:Testis / Q000473:pathology*