title: Arousal-modulated attention at four months as a function of intrauterine cocaine exposure and central nervous system injury.
abstract: CNS-compromised neonates are poor modulators tending to prefer less stimulation in all arousal conditions. Cocaine-exposed neonates also are poor modulators but tend to prefer more stimulation in all arousal conditions. Infants (N = 359, M = 4 months) were divided into 6 CNS injury groups and 1 cocaine-exposed, non-CNS-injured group and tested in three arousal conditions: less aroused (after feeding), more around-endogenous (before feeding), and more aroused-exogenous (after feeding with additional stimulation prior to each trial). Infants with CNS injuries still showed some degree of influence of arousal on attention that was now similar to that seen in normal neonates and 1-month-olds, while cocaine-exposed infants, 4-month-old normal and mild or moderate CNS-injury infants did not.
authors.affiliation: New York State Institute for Basic Research in Developmental Disabilities, Staten Island 10314, USA.
authors.forename: B Z
authors.initials: BZ
authors.lastname: Karmel
authors.forename: J M
authors.initials: JM
authors.lastname: Gardner
authors.forename: R L
authors.initials: RL
authors.lastname: Freedland
mesh_terms: D001143:Arousal; D001288:Attention; D001930:Brain Injuries / Q000139:chemically induced* / Q000503:physiopathology*; D016022:Case-Control Studies; D003042:Cocaine; D005260:Female; D006706:Homeostasis; D006801:Humans; D007223:Infant; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects
chemical_list: D003042:Cocaine