title: Model of a thalamocortical neurone with dendritic voltage-gated ion channels.
abstract: To investigate the functional role of dendrites of thalamocortical neurones, we have used our one-compartmental model to construct a multi-compartmental model with dendritic regions chosen according to a representative soma-to-dendritic terminal path of an X cell of the cat dorsal lateral geniculate nucleus. The multi-compartmental model with dendritic low-threshold Ca2+ and delayed rectifier K+ channels yields more accurate results than the one-compartmental model when simulating tonic firing and oscillatory activities, and provides a useful means for the study of propagation of excitation on the dendrites.
authors.affiliation: Physiology Unit, School of Molecular and Medical Biosciences, University of Wales Cardiff, UK.
authors.forename: K
authors.initials: K
authors.lastname: Antal
authors.forename: Z
authors.initials: Z
authors.lastname: Emri
authors.forename: T I
authors.initials: TI
authors.lastname: Tóth
authors.forename: V
authors.initials: V
authors.lastname: Crunelli
mesh_terms: D000818:Animals; D002415:Cats; D003712:Dendrites / Q000502:physiology*; D007473:Ion Channels / Q000502:physiology*; D008959:Models, Neurological; D013788:Thalamus / Q000502:physiology*
chemical_list: D007473:Ion Channels