title: Comparison of Tc-99m pertechnetate with Tl-201 and Ga-67 scintigraphy of malignant soft-tissue tumors.
abstract: Tc-99m pertechnetate scintigraphy was compared with Tl-201 chloride and Ga-67 citrate to evaluate the avidity of Tc-99m pertechtate for malignant soft-tissue tumors. Twenty-three patients with malignant soft-tissue tumors underwent scintigraphic studies. All 23 received Tc-99m and Tl-201, whereas 14 also were injected with Ga-67. In 21 (91%) of the 23 patients, Tc-99m accumulated extensively in the tumors. Tl-201 accumulated in 12 (52%) of the 23 tumors. Ga-67 accumulated in only 5 (36%) of the 14 tumors. The avidity of Tc-99m for myxoid tumors was markedly different from the other two agents. Tc-99m accumulated in all eight myxoid tumors, while neither Tl-201 or Ga-67 showed marked accumulation except for one patient with increased accumulation of Tl-201. This study shows that Tc-99m pertechnetate has the potential to localize malignant soft-tissue tumors and may be useful in the evaluation of these tumors.
authors.affiliation: National Cancer Center of Japan, Department of Diagnostic Radiology, Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Abe
authors.forename: S
authors.initials: S
authors.lastname: Terui
authors.forename: T
authors.initials: T
authors.lastname: Terauchi
authors.forename: Y
authors.initials: Y
authors.lastname: Muramatsu
authors.forename: R
authors.initials: R
authors.lastname: Yokayama
authors.forename: K
authors.initials: K
authors.lastname: Ohtomo
authors.forename: Y
authors.initials: Y
authors.lastname: Beppu
authors.forename: H
authors.initials: H
authors.lastname: Fukuma
mesh_terms: D005121:Extremities; D005260:Female; D005710:Gallium Radioisotopes; D018219:Histiocytoma, Benign Fibrous / Q000000981:diagnostic imaging; D006801:Humans; D008080:Liposarcoma / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D013670:Sodium Pertechnetate Tc 99m; D012983:Soft Tissue Neoplasms / Q000000981:diagnostic imaging*; D013794:Thallium Radioisotopes
chemical_list: D005710:Gallium Radioisotopes; D013794:Thallium Radioisotopes; D013670:Sodium Pertechnetate Tc 99m