title: Caffeine restriction has no role in the management of patients with symptomatic idiopathic ventricular premature beats.
abstract: OBJECTIVE
  To assess the role of caffeine restriction in the management of patients with symptomatic idiopathic ventricular premature beats.
  
  
  METHODS
  A randomised, double blind, 6 week intervention trial incorporating dietary caffeine restriction, caffeinated coffee, and decaffeinated coffee.
  
  
  METHODS
  Cardiac outpatient clinic.
  
  
  METHODS
  13 patients with symptomatic frequent idiopathic ventricular premature beats.
  
  
  METHODS
  Weekly measures of serum caffeine concentration, coffee consumption, visual analogue score of palpitations, and 24 hour ventricular premature beat frequency.
  
  
  RESULTS
  The interventions achieved significant alterations in serum caffeine concentrations (P < 0.001) which correlated with coffee consumption (r = 0.70; P < 0.001). Visual analogue palpitation scores showed a small, but significant correlation with ventricular premature beat frequencies (r = 0.34; P = 0.003). However, there were no significant changes in palpitation scores or ventricular premature beat frequencies during the intervention weeks and no significant correlations were found between these variables and serum caffeine concentrations.
  
  
  CONCLUSIONS
  Caffeine restriction has no role in the management of patients referred with symptomatic idiopathic ventricular premature beats.
authors.affiliation: Department of Cardiology, Royal Infirmary, Edinburgh.
authors.forename: D E
authors.initials: DE
authors.lastname: Newby
authors.forename: J M
authors.initials: JM
authors.lastname: Neilson
authors.forename: D R
authors.initials: DR
authors.lastname: Jarvie
authors.forename: N A
authors.initials: NA
authors.lastname: Boon
mesh_terms: D002110:Caffeine / Q000008:administration & dosage* / Q000097:blood; D004032:Diet; D004311:Double-Blind Method; D015716:Electrocardiography, Ambulatory; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018879:Ventricular Premature Complexes / Q000097:blood / Q000503:physiopathology / Q000628:therapy*
chemical_list: D002110:Caffeine