title: Underestimation and undertreatment of pain in HIV disease: multicentre study.
abstract: OBJECTIVE
  To measure the prevalence, severity, and impact of pain on quality of life for HIV patients; to identify factors associated with undertreatment of pain.
  
  
  METHODS
  Multicentre cross sectional survey.
  
  
  METHODS
  34 HIV treatment facilities, including inpatient hospital wards, day hospitals, and ambulatory care clinics, in 13 cities throughout France.
  
  
  METHODS
  315 HIV patients at different stages of the disease.
  
  
  METHODS
  
  
  
  METHODS
  recorded presence and severity of pain and rated quality of life. Doctors: reported disease status, estimate of pain severity, and analgesic treatment ordered.
  
  
  RESULTS
  From 30% (17/56) of outpatients to 62% (73/118) of inpatients reported pain due to HIV disease. Pain severity significantly decreased patients' quality of life. Doctors underestimated pain severity in 52% (70/135) of HIV patients reporting pain. Underestimation of pain severity was more likely for patients who reported moderate (odds ratio 24) or severe pain (165) and less likely for patients whose pain source was identified or who were perceived as more depressed. Of the patients reporting moderate or severe pain, 57% (61/107) did not receive any analgesic treatment; only 22% (23/107) received at least weak opioids. Likelihood of analgesic prescription increased when doctors estimated pain to be more severe and regarded patients as sicker.
  
  
  CONCLUSIONS
  Pain is a common and debilitating symptom of HIV disease which is gravely underestimated and undertreated.
authors.affiliation: Institut Mutualiste Montsouris, Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Larue
authors.forename: A
authors.initials: A
authors.lastname: Fontaine
authors.forename: S M
authors.initials: SM
authors.lastname: Colleau
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000553:Ambulatory Care; D000698:Analgesia; D000928:Antidepressive Agents / Q000627:therapeutic use; D003430:Cross-Sectional Studies; D003631:Day Care, Medical; D015658:HIV Infections / Q000503:physiopathology*; D006760:Hospitalization; D006801:Humans; D008875:Middle Aged; D009294:Narcotics / Q000627:therapeutic use; D010146:Pain / Q000209:etiology; D059408:Pain Management; D010147:Pain Measurement; D011788:Quality of Life
chemical_list: D000928:Antidepressive Agents; D009294:Narcotics