title: Enhanced thermogenesis in rats by Panax ginseng, multivitamins and minerals.
abstract: Substances which enhance endurance for physical and mental work and increase non-specific resistance to stress during a prolonged stay in physiologically adverse habitats are called 'adaptogens'. Panax ginseng is well known for its anti-stress and adaptogenic properties. In the present study, adaptogenic activity by the intake of a herbo-vitamin-mineral preparation (HVMP) containing P. ginseng and multivitamin-mineral preparation (MVMP) was evaluated using the cold-hypoxia-restrained (C-H-R) animal model. The aim was to determine whether the cold tolerance and recovery from acute hypothermia mediated by P. ginseng was modified by simultaneous intake of additional vitamins and minerals. Results suggest that the adaptogenic effect of HVMP was more or less the sum total of its two components P. ginseng and MVMP. In HVMP, P. ginseng was found to be effective for developing resistance to cooling and MVMP helped in stimulating faster recovery from acute hypothermia.
authors.affiliation: Defence Institute of Physiology and Allied Sciences, Timarpur, Dehli, India.
authors.forename: R
authors.initials: R
authors.lastname: Kumar
authors.forename: S K
authors.initials: SK
authors.lastname: Grover
authors.forename: H M
authors.initials: HM
authors.lastname: Divekar
authors.forename: A K
authors.initials: AK
authors.lastname: Gupta
authors.forename: R
authors.initials: R
authors.lastname: Shyam
authors.forename: K K
authors.initials: KK
authors.lastname: Srivastava
mesh_terms: D000064:Acclimatization / Q000187:drug effects / Q000502:physiology; D000818:Animals; D001833:Body Temperature Regulation / Q000187:drug effects* / Q000502:physiology; D008297:Male; D008903:Minerals / Q000494:pharmacology; D005894:Panax; D010807:Physical Endurance / Q000187:drug effects / Q000502:physiology; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar; D013312:Stress, Physiological / Q000517:prevention & control; D014815:Vitamins / Q000494:pharmacology
chemical_list: D008903:Minerals; D014815:Vitamins