Genetic variations at four tetrameric tandem repeat loci in Korean population.
Allele and genotype frequencies for four tetrameric short tandem repeat (STR) loci, HumFES/FPS, HumFOLP23, HumGABRB15, and HumCYAR04, have been determined by polymerase chain reaction (PCR) amplification and subsequent polyacrylamide gel electrophoresis from approximately 200 genetically unrelated Koreans. This method allows a single base pair resolution and rapid typing with silver staining. The allele and genotype distributions satisfy Hardy-Weinberg expectation. Also, these STR loci have proven to be useful for forensic analyses and paternity tests in which the variable number of tandem repeat (VNTR) loci have some limitations.
Park
S J
SJ
Department of Biology, Inje University, Kimhae, Korea.
Lee
W G
WG
Lee
S W
SW
Kim
S H
SH
Koo
B S
BS
Budowle
B
B
Rho
H M
HM
D000483:Alleles; D044466:Asian People / Q000235:genetics*; D001483:Base Sequence; D004591:Electrophoresis, Polyacrylamide Gel; D005554:Forensic Medicine; D014644:Genetic Variation; D005828:Genetics, Population; D005838:Genotype; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D007723:Korea / Q000208:ethnology; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012091:Repetitive Sequences, Nucleic Acid / Q000235:genetics*