[Diabetes mellitus after renal transplant].
Posttransplant Diabetes Mellitus (PTDM) has traditionally been attributed to therapy with steroids, however with the introduction of Cyclosporine (cya) into clinical practice, an increase in the incidence of PTDM was noted. We studied the prevalence of PTDM in Renal transplant recipients and its clinical characteristics.


METHODS
355 patients were submitted to a renal transplant between 30/06/80 and 31/12/92. After stabilization of the doses of the immunosuppressive therapy we considered diabetic patients those with fasting glycemic values > or = 140 mg/dl and those with glycemic values between 100-140 mg/dl were given to an oral glucose tolerance test (WHO criteria 1985).


RESULTS
Posttransplant diabetes mellitus occurred in 28 patients (7.9%), 11 females with a mean age of 53.36 +/- 12.75 years and 17 males with a mean age of 51.05 +/- 10.60 years.


CONCLUSIONS
Due to the great prevalence of alterations in glucose tolerance and their adverse effects on the cardio-vascular system, we think that all renal transplant recipients should be screened.
Ruas
L
L
Serviço de Urologia e Transplantação, H.U.C. Coimbra.
Bastos
M
M
Alves
R
R
Gomes
H
H
Rodrigues
D
D
Barros
L
L
Mota
A
A
Carvalheiro
M
M
Furtado
A R
AR
D000328:Adult; D000368:Aged; D003920:Diabetes Mellitus / Q000453:epidemiology*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies
D007166:Immunosuppressive Agents