title: Oesophagogastrectomy for carcinoma in patients under 50 years of age.
abstract: Oesophagogastrectomy for carcinoma of the oesophagus or gastric cardia has been reported as being associated with a poorer outcome in young adults than in older patients in an Oriental population. A retrospective analysis of 597 patients who underwent oesophagogastrectomy for carcinoma was undertaken to ascertain if resection in younger Scottish patients was associated with the same poorer outcome. Forty-seven patients aged less than 50 years were compared with 323 patients aged 50-69 years and 227 patients aged 70 years and older. Young patients had a higher incidence of distal third oesophageal tumours than older patients, who tended to have carcinomas of the gastric cardia. There were no differences with regard to tumour pathology, stage, extent of resection, hospital mortality or survival. In Scotland, carcinoma of the oesophagus or gastric cardia in young adults behaves similarly to that in older patients, and survival following resection is independent of age.
authors.affiliation: Department of Cardiothoracic Surgery, Royal Infirmary of Edinburgh, UK.
authors.forename: D J
authors.initials: DJ
authors.lastname: Adam
authors.forename: S R
authors.initials: SR
authors.lastname: Craig
authors.forename: C T
authors.initials: CT
authors.lastname: Sang
authors.forename: W S
authors.initials: WS
authors.lastname: Walker
authors.forename: E W
authors.initials: EW
authors.lastname: Cameron
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D002277:Carcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D002299:Cardia / Q000473:pathology / Q000601:surgery; D004938:Esophageal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012606:Scotland / Q000453:epidemiology; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016019:Survival Analysis