title: Frequency of metabolic bone disease in haemodialysis patients.
abstract: The frequency of metabolic bone disease related to secondary hyperparathyroidism was studied in 47 haemodialysis patients, using biochemical, radiological parameters and bone biopsy (30 males, 17 females; mean age 48 years). The duration on dialysis ranged from 1-5 years. Hypocalcemia was found in 47% while 62% had raised phosphorus levels and 49% raised alkaline phosphatase. Serum parathyroid hormone was elevated in 86%, while in 13% it was markedly raised. On radiological examination there was generalized osteopenia in 49% and decreased bone density in 21%. In 30% no radiological abnormality was detected. In 40% bone biopsy revealed osteomalacia, mixed osteodystrophy 21%, osteoporosis 8.5% and in 25% no histological abnormality was observed.
authors.affiliation: Kidney Centre, Karachi.
authors.forename: R
authors.initials: R
authors.lastname: Hussain
authors.forename: A
authors.initials: A
authors.lastname: Ahmed
authors.forename: A S
authors.initials: AS
authors.lastname: Soomro
authors.forename: S H
authors.initials: SH
authors.lastname: Chishty
authors.forename: S A
authors.initials: SA
authors.lastname: Naqvi
mesh_terms: D001851:Bone Diseases, Metabolic / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006801:Humans; D006962:Hyperparathyroidism, Secondary / Q000209:etiology; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects*