title: [Fine needle puncture--method of treatment in nodular pathology of the thyroid].
abstract: Fine needle biopsy (FNB) has been used as a therapeutic method in different nodular lesions of the thyroid. Between 1989-1995, 295 subjects with thyroid cysts, 235 women and 60 men have been treated by FNB. The treatment of cysts was performed by: one or multiple aspirations in 207 cases, sclerosis by injection with tetracycline in 77 cases and by ethanol washing in 11 cases. 263 (89.11%) cases have been cured and we have lost track of 32 cases in the survey. Of the 207 cases treated by aspiration, 177 (86.5%) have been cured after one or more aspirations. Of the 77 cases treated by injections with tetracycline, 75 (97.26%) displayed sclerosis after one or more injections. All 11 cases treated by ethanol washing method displayed sclerosis. Between 1993-1995 we used percutaneous ethanol injection (PE1) in 6 cases, as an alternative to the classic treatment, in order to induce necrosis of toxic adenoma. After 1 to 9 injections all cases were cured, with the appearance of the entire image of the gland on the scintigram. In 4 cases of cold nodules with benign cytology PEI, induced a significant decrease of volume appreciated by sonography.
authors.affiliation: Service d'Endocrinologie, Université de Médecine et Pharmacie Gr. T. Popa, Iasi Roumanie.
authors.forename: E
authors.initials: E
authors.lastname: Zbranca
authors.forename: V
authors.initials: V
authors.lastname: Mogos
authors.forename: C
authors.initials: C
authors.lastname: Vulpoi
authors.forename: T
authors.initials: T
authors.lastname: Bostaca
authors.forename: M
authors.initials: M
authors.lastname: Rusu
authors.forename: G
authors.initials: G
authors.lastname: Nisfoeanu
authors.forename: C
authors.initials: C
authors.lastname: Galesanu
authors.forename: C
authors.initials: C
authors.lastname: Nestor
authors.forename: G
authors.initials: G
authors.lastname: Natasa Macovei
mesh_terms: D000236:Adenoma / Q000628:therapy; D000279:Administration, Cutaneous; D000293:Adolescent; D000328:Adult; D000368:Aged; D001707:Biopsy, Needle / Q000295:instrumentation / Q000379:methods*; D002648:Child; D003560:Cysts / Q000628:therapy; D000431:Ethanol / Q000008:administration & dosage / Q000494:pharmacology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013752:Tetracycline / Q000008:administration & dosage / Q000494:pharmacology; D013959:Thyroid Diseases / Q000628:therapy; D013964:Thyroid Neoplasms / Q000628:therapy; D016606:Thyroid Nodule / Q000628:therapy*
chemical_list: D000431:Ethanol; D013752:Tetracycline