[Oncocytic tumors of the thyroid. Diagnostic and therapeutic problems. Report of 17 cases and review of the literature].
Histopathologic and clinical follow-up data of 17 patients observed 3-104 months (mean: 38 months) after operation for oncocytic tumors of the thyroid gland are presented. Mean patient age was 50 +/- 15 years. Benign and malignant lesions were respectively 13 and 4. Frozen sections were positive for benign and malignant lesions in respectively 7 and 2 cases. Total thyroidectomy was performed in all cases of malignant lesions and in 7 cases of benign lesion, the latter in order to treat high volume adenomas or associated controlateral lesions. No tumor relapse was observed during the follow-up period (data about 16 patients). A review of the literature indicates that thyroid oncocytic adenoma diagnosis can be trusted and that this tumor is not especially prone to a malignant course with the mode of treatment applied. Thus total thyroidectomy should be recommended for: 1) malignant tumors. 2) and for selected benign adenomas depending on the tumor volume or on associated lesions.
Gaschignard
N
N
Service de Chirurgie Générale I, Hôpital G. et R. Laennec, Nantes.
Letessier
E
E
Hamy
A
A
Sagan
C
C
Cuillière
P
P
Courant
O
O
Paineau
J
J
Visset
J
J
D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D018249:Adenoma, Oxyphilic / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D013965:Thyroidectomy / Q000379:methods