Chemotherapy in Hodgkin's disease.
OBJECTIVE
To assess the efficacy of primary chemotherapy in patients with clinically staged Hodgkin's disease.


METHODS
Non randomized study.


METHODS
Pediatric Oncology Division of Regional Cancer Center.


METHODS
Twenty nine children with Hodgkin's disease.


METHODS
Chemotherapy was given to 21 patients whose parents agreed for the same. Sixteen children received COPP regimen and 5 received MOPP regimen.


RESULTS
Complete remission was achieved in 19 patients. The relapse free survival and overall survival in these patients were 76% and 86%, respectively at 5 years. There was no death related to chemotherapy toxicity.


CONCLUSIONS
Combination chemotherapy is an effective modality of treatment for children with Hodgkin's disease.
Kumari
P K
PK
Department of Pediatric Oncology, Regional Cancer Center, Trivandrum.
Chellam
V G
VG
Madhavan
J
J
Ratheesan
K
K
Pillai
G R
GR
Kumar
S R
SR
Nair
M K
MK
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003520:Cyclophosphamide / Q000008:administration & dosage; D018572:Disease-Free Survival; D004317:Doxorubicin / Q000008:administration & dosage; D005260:Female; D006689:Hodgkin Disease / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008466:Mechlorethamine / Q000008:administration & dosage; D011241:Prednisone / Q000008:administration & dosage; D011344:Procarbazine / Q000008:administration & dosage; D015996:Survival Rate; D014750:Vincristine / Q000008:administration & dosage
D011344:Procarbazine; D008466:Mechlorethamine; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone