title: Molecular structure of terrecyclodiol: a derivative of the antifungal metabolite terrecyclic acid A from Aspergillus terreus.
abstract: A strain of Aspergillus terreus, which was isolated from organic mulch and inhibited the growth of the plant pathogen Phytophthora cinnamomi, produces an antifungal metabolite when grown in liquid culture. This metabolite was isolated by bioassay-guided fractionation and identified as terrecyclic acid A (1). X-ray diffraction studies and spectroscopic details of the derived terrecyclodiol (2) are described.
authors.affiliation: Department of Chemistry, University of Western Australia, Nedlands.
authors.forename: F
authors.initials: F
authors.lastname: Almassi
authors.forename: E L
authors.initials: EL
authors.lastname: Ghisalberti
authors.forename: B W
authors.initials: BW
authors.lastname: Skelton
authors.forename: A H
authors.initials: AH
authors.lastname: White
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry* / Q000302:isolation & purification; D001230:Aspergillus / Q000737:chemistry* / Q000378:metabolism; D003460:Crystallization; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008968:Molecular Conformation; D010838:Phytophthora / Q000187:drug effects; D012717:Sesquiterpenes / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology; D014961:X-Ray Diffraction
chemical_list: D000935:Antifungal Agents; D012717:Sesquiterpenes; C102613:terrecyclodiol; C036622:terrecyclic acid A