title: Antimicrobial resistance in organisms causing diarrheal disease.
abstract: Antimicrobial resistance is becoming increasingly important in the treatment of enteric infections, particularly those due to Shigella, Vibrio cholerae, enterotoxigenic Escherichia coli (associated with traveler's diarrhea), and Salmonella typhi. The rate of antimicrobial resistance is highest in the developing world, where the use of antimicrobial drugs is relatively unrestricted. Of greatest immediate concern is the need for an effective, inexpensive antimicrobial that can be used safely as treatment for small children with dysentery due to Shigella, primarily Shigella dysenteriae type 1.
authors.affiliation: Division of Community Health, International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka.
authors.forename: R B
authors.initials: RB
authors.lastname: Sack
authors.forename: M
authors.initials: M
authors.lastname: Rahman
authors.forename: M
authors.initials: M
authors.lastname: Yunus
authors.forename: E H
authors.initials: EH
authors.lastname: Khan
mesh_terms: D016123:Campylobacter jejuni / Q000187:drug effects; D016360:Clostridioides difficile / Q000187:drug effects; D003906:Developing Countries; D004352:Drug Resistance, Microbial; D004403:Dysentery / Q000188:drug therapy* / Q000382:microbiology*; D004926:Escherichia coli / Q000187:drug effects; D006801:Humans; D012485:Salmonella typhi / Q000187:drug effects; D012760:Shigella / Q000187:drug effects; D014734:Vibrio cholerae / Q000187:drug effects