title: Analgesic effect of epidural morphine in lumbar disc surgery.
abstract: In patients operated on for herniated lumbar disc, epidural morphine was administered intraoperatively at the end of the procedure. A 10 milligram dose of morphine provided significant pain relief expressed by less requirement for strong analgesics on the day of operation and the day following, as well as for sedatives during the postoperative observation period of four days in comparison to a control group of patients. The only side effect observed was urinary retention.
authors.affiliation: Neurosurgical Clinic, Nordstadt Hospital, Hannover, Fed. Rep. of Germany.
authors.forename: A
authors.initials: A
authors.lastname: Sepehrnia
authors.forename: W J
authors.initials: WJ
authors.lastname: van Ouwerkerk
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015360:Analgesia, Epidural / Q000009:adverse effects; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage; D007405:Intervertebral Disc Displacement / Q000601:surgery*; D007432:Intraoperative Period; D008159:Lumbar Vertebrae / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage* / Q000009:adverse effects; D010149:Postoperative Pain / Q000517:prevention & control*; D016055:Urinary Retention / Q000209:etiology
chemical_list: D006993:Hypnotics and Sedatives; D009020:Morphine