An unusual complication of diabetes mellitus: the zebra that became a horse.
A 41-year-old black woman with a history of well-controlled, insulin-dependent diabetes mellitus was in her usual state of relatively good health when she had acute onset of right upper quadrant and epigastric abdominal pain, nausea, and vomiting. Physical examination and laboratory evaluation revealed gastrointestinal hemorrhage, decreased mental status, and acidemia, and emergency exploratory laparotomy elucidated ischemic bowel, of which 90 cm was resected. Postoperatively, the patient had cardiac arrest and could not be resuscitated. Autopsy was remarkable for mesenteric venous thrombosis and pylethrombosis, with ischemic necrosis of bowel and passive hyperemia. The arterial side of the cardiovascular system was relatively unaffected. Although arterial vascular complications of diabetes mellitus are well known, venous complications are less well described.
Nicol
K K
KK
Department of Pathology, Bowman Gray School of Medicine, Winston-Salem, NC, USA.
Davis
G J
GJ
D015746:Abdominal Pain / Q000209:etiology*; D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007238:Infarction / Q000209:etiology*; D007421:Intestine, Small / Q000098:blood supply*; D008641:Mesenteric Vascular Occlusion / Q000209:etiology*; D008642:Mesenteric Veins; D011169:Portal Vein; D013927:Thrombosis / Q000209:etiology*