[The detection of pathogenicity factors in the nematode Trichinella spiralis at different stages of its development].
The study of water soluble proteins of Trichinella spiralis has discovered for the first time some protein fractions having neiraminedase, haemagglutinative and cytotoxic activities. The presence of hyaluronidase was confirmed and its activity both for water soluble and cuticle proteins of the trichinella was examined. The haemagglutinin and cytotoxin of the trichinella have an antigen specificity. The presence of active molecules is considered as the factors of pathogenicity. These pathogenic factors were discovered in the invading larvae and adult Trichinella, while they were not found in young larvae.
Vaserin
Iu I
IuI
Sivovolova
I A
IA
Nagornyĭ
S A
SA
D000818:Animals; D006388:Hemagglutinins / Q000378:metabolism; D007814:Larva / Q000254:growth & development / Q000276:immunology / Q000378:metabolism / Q000472:pathogenicity; D009439:Neuraminidase / Q000378:metabolism; D011506:Proteins / Q000378:metabolism; D051381:Rats; D012995:Solubility; D017160:Trichinella spiralis / Q000254:growth & development / Q000276:immunology / Q000378:metabolism / Q000472:pathogenicity*; D014235:Trichinellosis / Q000209:etiology / Q000469:parasitology
D006388:Hemagglutinins; D011506:Proteins; D009439:Neuraminidase