Isolation of guaianoid pigments from the gorgonian Calicogorgia granulosa.
Three pigments of the guaiazulene class have been isolated from the gorgonian Calicogorgia granulosa. Structures of these compounds have been determined as guaiazulene, 2,2'- diguaiazulenylmethane, and a new compound, 2,2'-biguaiazulenyl, by combined chemical and spectroscopic methods. 2,2'-Biguaiazulenyl exhibited moderate antimicrobial activity.
Seo
Y
Y
Marine Natural Products Chemistry Laboratory, Korea Ocean Research & Development Institute, Seoul, Korea.
Rho
J R
JR
Geum
N
N
Yoon
J B
JB
Shin
J
J
D000818:Animals; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000302:isolation & purification* / Q000494:pharmacology; D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology; D052176:Azulenes; D001412:Bacillus subtilis / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D003063:Cnidaria / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D012717:Sesquiterpenes / Q000302:isolation & purification* / Q000494:pharmacology; D045789:Sesquiterpenes, Guaiane
C102489:2,2'-biguaiazulenyl; C102490:2,2'-diguaiazulenylmethane; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D052176:Azulenes; D012717:Sesquiterpenes; D045789:Sesquiterpenes, Guaiane; C004451:guaiazulene