Recent data on hypertension and progressive renal disease.
Arterial hypertension may favour the progression of non-diabetic primary renal disease and participate in the appearance of atheromatous renovascular disease. In AIPRI trial (ACE-inhibition in the progression of renal insufficiency) the ACE-inhibitor benazepril was able to protect patients with mild-to-moderate renal disease against the progression of renal insufficiency. Some clinical observations suggest that in many aged patients with long-standing hypertension the appearance of renal failure may be related to atheromatous reno-vascular disease. This disease may be responsible for progressive renal failure through renal artery stenosis and/or cholesterol microembolization.
Zucchelli
P
P
Malpighi Department of Nephrology, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Zuccalà
A
A
D018450:Disease Progression; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy; D051437:Renal Insufficiency / Q000188:drug therapy / Q000209:etiology*