title: [Gastric adenocarcinoma in hamartomatous polyp in Peutz-Jeghers syndrome].
abstract: The Peutz-Jeghers syndrome is characterized by gastrointestinal polyposis and mucocutaneous melanin pigmentation. Between the complications are the appearance of gastrointestinal neoplasms. There is an increasing evidence suggesting the hamartoma-adenoma-carcinoma sequence in Peutz-Jeghers syndrome. We present a 32-years-old man with Peutz-Jeghers syndrome who developed an adenocarcinoma arising in a gastric hamartomatous polyp. We discuss the risk to develop gastrointestinal neoplasms and the necessity for periodic surveillance.
authors.affiliation: Servicio de Digestivo, Hospital Nuestra Señora de Aránzazu, San Sebastián.
authors.forename: L
authors.initials: L
authors.lastname: Bujanda
authors.forename: A
authors.initials: A
authors.lastname: Beguiristain
authors.forename: J M
authors.initials: JM
authors.lastname: Villar
authors.forename: A
authors.initials: A
authors.lastname: Cosme
authors.forename: A
authors.initials: A
authors.lastname: Castiella
authors.forename: J A
authors.initials: JA
authors.lastname: Arriola
authors.forename: J I
authors.initials: JI
authors.lastname: Arenas
mesh_terms: D000230:Adenocarcinoma / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D000328:Adult; D001706:Biopsy; D005743:Gastrectomy; D005763:Gastroenterostomy; D006222:Hamartoma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007583:Jejunum / Q000601:surgery; D008207:Lymphatic Metastasis; D008297:Male; D010580:Peutz-Jeghers Syndrome / Q000150:complications*; D011127:Polyps / Q000150:complications* / Q000473:pathology / Q000601:surgery; D013270:Stomach / Q000473:pathology; D013274:Stomach Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery