[Level of endothelin-1,2,6-keto-pgf1-alpha and atrial natriuretic peptide in serum of pregnant women with late hypertension].
The etiology of late hypertension (LH) in pregnant women is still unknown. The purpose of this study was to measure the circulatory levels of endothelin-1,2 (ET-1,2), 6-keto-PGF1-alfa as a major metabolite of prostacyclin, and atrial natriuretic peptide (ANP) in the serum of pregnant women with LH, and in the serum of control healty pregnant women, and control healthy nonpregnant women.


RESULTS
The mean level of ET-1,2 among pregnant women with LH did not show any significant difference compared to control group. Serum 6-keto-PGF1-alfa levels was significantly higher (p < 0.001) in healthy pregnant women than in those of the pregnant women with LH and of healthy nonpregnant women. Serum ANP was significantly higher (p < 0.01) in the pregnant women with LH compared to healthy pregnant women and healthy nonpregnant women (p < 0.001). Among the women with LH there was no correlation between ET-1,2, 6-keto-PGF1-alfa and ANP.
Halawa
B
B
Katedra i Klinika Kardiologii AM we Wroclawiu.
Robaczyński
J
J
D015121:6-Ketoprostaglandin F1 alpha / Q000031:analogs & derivatives* / Q000097:blood; D000328:Adult; D009320:Atrial Natriuretic Factor / Q000097:blood*; D016232:Endothelins / Q000097:blood*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood*
D016232:Endothelins; C103103:endothelin-1,2-6-keto-PGF1-alpha; D015121:6-Ketoprostaglandin F1 alpha; D009320:Atrial Natriuretic Factor