[Myocardial perfusion scintigraphy using 99mTC-tetrofosmin: a comparison with coronary angiography].
OBJECTIVE
Coronary angiography is still the most reliable method for the detection of coronary artery disease. In this study we compared to this method the accuracy of 99mTc-Tetrofosmin myocardial SPECT.


METHODS
Fifty two patients (38 male and 14 female) were studied with stress-rest 99mTc-Tetrofosmin myocardial SPECT. Two independent observers evaluated the uptake of the radiotracer using a score from 0 to 4. All patients underwent coronary angiography and the results were compared to SPECT findings. We considered as hemodynamic significant any obstruction greater than 50% and as ischemic any myocardial region with radiotracer uptake less than 4 at stress.


RESULTS
There was good segmental correspondence between tetrofosmin scintigram and angiography. Sensitivity 72.2-91.1%, specificity 80.0-88.2%, ppv 76.4-88.5% and npv 83.3-85.7%, depending on the obstructed vessel.


CONCLUSIONS
99mTc-Tetrofosmin myocardial SPECT is a reliable alternative for the detection of CAD.
Georgoulias
P
P
Nuklearmedizinischen Abteilung, NIMT epsilon-Krankenhaus, Athen, Griechenland.
Demakopoulos
N
N
Kontos
A
A
Xaplanteris
P
P
Thomadakis
K
K
Mortzos
G
G
Karkavitsas
N
N
D000328:Adult; D000368:Aged; D017023:Coronary Angiography; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009943:Organophosphorus Compounds / Q000627:therapeutic use*; D015609:Organotechnetium Compounds / Q000627:therapeutic use*; D019275:Radiopharmaceuticals / Q000627:therapeutic use; D012680:Sensitivity and Specificity; D015899:Tomography, Emission-Computed, Single-Photon
D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C078700:technetium tc-99m tetrofosmin