title: [Detection of the functionally active domains in the molecule of the lethal factor of the anthrax exotoxin].
abstract: Three functional domains were revealed in the molecule of the lethal factor of B. anthracis. They are located in the linear structure of the molecula as follows: the associative domain occupies the area from Lys39 to Met242, the stabilizing domain from Leu517 to Lys614, and the effector domain still further to the COOH-terminal Lys mino acid.
authors.forename: A N
authors.initials: AN
authors.lastname: Noskov
authors.forename: T B
authors.initials: TB
authors.lastname: Kravchenko
authors.forename: V P
authors.initials: VP
authors.lastname: Noskova
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000942:Antigens, Bacterial; D001408:Bacillus anthracis / Q000737:chemistry*; D001427:Bacterial Toxins / Q000302:isolation & purification* / Q000378:metabolism; D001667:Binding, Competitive; D005098:Exotoxins / Q000302:isolation & purification* / Q000378:metabolism; D051379:Mice; D008808:Mice, Inbred CBA; D008969:Molecular Sequence Data
chemical_list: D000942:Antigens, Bacterial; D001427:Bacterial Toxins; D005098:Exotoxins; C030325:anthrax toxin