title: Severe falciparum malaria with hyperparasitaemia: management without exchange blood transfusion.
abstract: The risk of complication in falciparum malaria is associated with parasite load. Drug therapy alone may be insufficient, and blood exchange transfusion is indicated when more than 10% of erythrocytes are parasitized with concurrent pulmonary, renal, cerebral or haemostatic complications; without complications, when the parasitized erythrocytes exceed 30%. The successful use of conventional malaria therapy without exchange transfusion in a young woman with severe falciparum malaria is reported.
authors.affiliation: Hospital Universitário Júlio Müller, School of Medicine, Federal University of Mato Grosso, Cuiabá, Brazil.
authors.forename: C J
authors.initials: CJ
authors.lastname: Fontes
authors.forename: S
authors.initials: S
authors.lastname: Munhoz
mesh_terms: D000293:Adolescent; D000818:Animals; D000962:Antimalarials / Q000627:therapeutic use*; D002738:Chloroquine / Q000627:therapeutic use*; D005260:Female; D005313:Fetal Death; D006801:Humans; D016778:Malaria, Falciparum / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D010963:Plasmodium falciparum / Q000302:isolation & purification; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000188:drug therapy*; D011803:Quinine / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D000962:Antimalarials; D002738:Chloroquine; D011803:Quinine