Product binding and role of the C-terminal region in class I D-fructose 1,6-bisphosphate aldolase.
The structure of fructose 1,6-bisphosphate aldolase shows three distinct modes of product binding that are correlated to the disposition of the C-terminal region and depicts a possible trajectory for product exchange. The structure also indicates binding preference for monobasic triose phosphates.
Blom
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Sygusch
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D000818:Animals; D001665:Binding Sites; D005634:Fructose-Bisphosphate Aldolase / Q000737:chemistry / Q000378:metabolism*; D011485:Protein Binding; D011487:Protein Conformation; D011817:Rabbits
D005634:Fructose-Bisphosphate Aldolase