SOX20, a new member of the SOX gene family, is located on chromosome 17p13.
SOX genes share a high sequence identity with the HMG box present in the testis determining gene SRY. We have identified a HMG box-like sequence motif on six contiguous cosmids, which cross-hybridize to a SOX9 cDNA probe. A data base search revealed a high similarity of the deduced amino acid sequence to the human SOX12 and the murine Sox16 HMG domains. The cosmids were assigned to chromosome 17p13 by FISH analysis.
Meyer
J
J
Institute of Human Genetics, University of Freiburg, Germany.
Wirth
J
J
Held
M
M
Schempp
W
W
Scherer
G
G
D000595:Amino Acid Sequence; D001483:Base Sequence; D002886:Chromosomes, Human, Pair 17 / Q000235:genetics*; D004268:DNA-Binding Proteins / Q000235:genetics*; D006609:High Mobility Group Proteins / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D055747:SOX Transcription Factors
D004268:DNA-Binding Proteins; D006609:High Mobility Group Proteins; D055747:SOX Transcription Factors; C102810:SOX15 protein, human