title: Fusaricide, a new cytotoxic N-hydroxypyridone from Fusarium sp.
abstract: A new cytotoxic N-hydroxypyridone, fusaricide (1), was isolated from a Fusarium sp. Its structure was solved by X-ray diffraction and spectroscopic analyses.
authors.affiliation: Bristol-Myers Squibb Company, Pharmaceutical Research Institute, Wallingford, Connecticut 06492, USA.
authors.forename: K D
authors.initials: KD
authors.lastname: McBrien
authors.forename: Q
authors.initials: Q
authors.lastname: Gao
authors.forename: S
authors.initials: S
authors.lastname: Huang
authors.forename: S E
authors.initials: SE
authors.lastname: Klohr
authors.forename: R R
authors.initials: RR
authors.lastname: Wang
authors.forename: D M
authors.initials: DM
authors.lastname: Pirnik
authors.forename: K M
authors.initials: KM
authors.lastname: Neddermann
authors.forename: I
authors.initials: I
authors.lastname: Bursuker
authors.forename: K F
authors.initials: KF
authors.lastname: Kadow
authors.forename: J E
authors.initials: JE
authors.lastname: Leet
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001578:Benzopyrans / Q000302:isolation & purification* / Q000494:pharmacology; D018360:Crystallography, X-Ray; D005658:Fungi / Q000187:drug effects; D005670:Fusarium / Q000737:chemistry*; D015967:Gene Expression Regulation, Viral / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011728:Pyridones / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured; D014771:Virion / Q000187:drug effects
chemical_list: D000935:Antifungal Agents; D000970:Antineoplastic Agents; D001578:Benzopyrans; D011728:Pyridones; C103980:fusaricide