title: [Ofloxacin in comprehensive treatment of infections in burn patients].
abstract: The experience with ofloxacin in the prophylaxis and treatment of infected burn wounds in 40 patients was investigated. High clinical and microbiological efficacy of the drug was stated (82.5 and 83 per cent respectively). The highest efficacy of ofloxacin was observed when the burned area did not exceed 25 per cent of the body surface. It was concluded that the prophylactic use of the drug during acute burn toxemia was not expedient.
authors.forename: M G
authors.initials: MG
authors.lastname: Krutikov
authors.forename: A A
authors.initials: AA
authors.lastname: Alekseev
authors.forename: L V
authors.initials: LV
authors.lastname: Elagina
authors.forename: G N
authors.initials: GN
authors.lastname: Izotova
authors.forename: V P
authors.initials: VP
authors.lastname: Iakovlev
mesh_terms: D000328:Adult; D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D002056:Burns / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015242:Ofloxacin / Q000627:therapeutic use*; D014115:Toxemia / Q000188:drug therapy* / Q000382:microbiology / Q000517:prevention & control; D016896:Treatment Outcome; D014946:Wound Infection / Q000188:drug therapy* / Q000382:microbiology / Q000517:prevention & control
chemical_list: D000890:Anti-Infective Agents; D015242:Ofloxacin