title: [Experience in treating Nephroblastomas].
abstract: The treatment of nephroblastomas which accounts for 72% of all malignant neoplasms in children is one of the topical problems of pediatric oncology. To detect the tumor at early stages of a tumorous process is one of the main conditions of successful treatment for nephroblastomas. The histological types of nephroblastoma, its international classifications and present-day treatment policy are given. A role of radiation treatment is shown at pre- and postoperative therapeutical stages. Drugs, their combinations, and the efficiency of polychemotherapy regimens in use are outlined. The importance of comprehensive examination of the patient to determine the extent of malignancy and to choose adequate antitumor treatment regimens is emphasized.
authors.affiliation: NII of Pediatric Oncology, ONTs RAMN, Moscow.
authors.forename: V I
authors.initials: VI
authors.lastname: Lebedev
authors.forename: I V
authors.initials: IV
authors.lastname: Pashkov
authors.forename: E I
authors.initials: EI
authors.lastname: Boichenko
authors.forename: T A
authors.initials: TA
authors.lastname: Sharov
authors.forename: G E
authors.initials: GE
authors.lastname: Zaeva
authors.forename: I N
authors.initials: IN
authors.lastname: Sokolova
authors.forename: I V
authors.initials: IV
authors.lastname: Glekov
authors.forename: G L
authors.initials: GL
authors.lastname: Mentkevich
authors.forename: Z S
authors.initials: ZS
authors.lastname: Ordukhanian
mesh_terms: D002675:Child, Preschool; D003131:Combined Modality Therapy; D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000145:classification / Q000175:diagnosis / Q000628:therapy*; D009367:Neoplasm Staging; D016896:Treatment Outcome; D009396:Wilms Tumor / Q000145:classification / Q000175:diagnosis / Q000628:therapy*