title: [A case of ventricular septal defect closure in patient with cytomegalo virus hepatitis].
abstract: Cytomegalovirus (CMV) infection has been reported to cause serious event in nonimmunocompromised patients after major surgery. Particularly in active case, the indication of surgical intervention is a difficult issue. A 7-months-old boy with ventricular septaldefect (VSD) has been diagnosed with CMV hepatitis. As his heart failure was not controlled with medication, he underwent closure of VSD at 9 months of age while CMV was still detected in the urine and serum by polymerase chain reaction method. During post operative course, he was treated with ganciclovir and intravenous CMV hyperimmune grobiln, and CMV in the serum became negative and he develops no aggravation of the CMV infection postoperatively.
authors.affiliation: First Department of Surgery, Osaka University Medical School, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Taketani
authors.forename: N
authors.initials: N
authors.lastname: Fukushima
authors.forename: K
authors.initials: K
authors.lastname: Kadoba
authors.forename: H
authors.initials: H
authors.lastname: Imagawa
authors.forename: M
authors.initials: M
authors.lastname: Taya
authors.forename: H
authors.initials: H
authors.lastname: Matsuda
mesh_terms: D000998:Antiviral Agents / Q000008:administration & dosage; D003587:Cytomegalovirus / Q000276:immunology; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000628:therapy; D015774:Ganciclovir / Q000008:administration & dosage; D006345:Heart Septal Defects, Ventricular / Q000150:complications* / Q000601:surgery*; D006525:Hepatitis, Viral, Human / Q000150:complications* / Q000628:therapy; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage; D007223:Infant; D008297:Male
chemical_list: D000998:Antiviral Agents; D016756:Immunoglobulins, Intravenous; D015774:Ganciclovir