title: Growth of the uterus.
abstract: BACKGROUND
  The pattern of growth of the uterus was examined by ultrasound examinations of 358 girls who attended a paediatric endocrine outpatient department but were shown not to have any endocrine defect.
  
  
  METHODS
  The uterus was measured in length and width at the cervix and at the fundus (cm). Endometrial thickness was measured (mm). Scans were divided by Tanner breast stage and the dimensions compared by one way analysis of variance (ANOVA, with the Student Newman Keuls post hoc test).
  
  
  RESULTS
  There was an increase in uterine length, diameter of the fundus, and endometrial thickness at each breast stage from 1 to 5 (ANOVA, p < 0.05), and in the diameter of the cervix with each breast stage from 1 to 4 (ANOVA, p < 0.05). The ratio of the fundus to the cervix increased from 0.95 to 1.29 between breast stages 1 and 4.
  
  
  CONCLUSIONS
  The onset of puberty is marked by an increase in the dimensions of the uterus and in endometrial thickness, but also by a change in the shape of the uterus from a tubular to a pear shaped organ.
authors.affiliation: London Centre for Paediatric Endocrinology and Metabolism, Middlesex Hospital, London.
authors.forename: N A
authors.initials: NA
authors.lastname: Bridges
authors.forename: A
authors.initials: A
authors.lastname: Cooke
authors.forename: M J
authors.initials: MJ
authors.lastname: Healy
authors.forename: P C
authors.initials: PC
authors.lastname: Hindmarsh
authors.forename: C G
authors.initials: CG
authors.lastname: Brook
mesh_terms: D000293:Adolescent; D001940:Breast / Q000254:growth & development; D002584:Cervix Uteri / Q000000981:diagnostic imaging / Q000254:growth & development; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011627:Puberty / Q000502:physiology*; D014463:Ultrasonography; D014599:Uterus / Q000000981:diagnostic imaging / Q000254:growth & development*