Structural requirements of chiral clofibric acid analogs for activation of the rat peroxisome proliferator-activated receptor alpha.
Feller
D R
DR
College of Pharmacy, Ohio State University, Columbus 43210, USA.
O'Brien
M
M
Rangwala
S M
SM
Tortorella
V
V
Loiodice
F
F
Noonan
D J
DJ
D042962:Acyl-CoA Oxidase; D000818:Animals; D002460:Cell Line; D002522:Chlorocebus aethiops; D002995:Clofibric Acid / Q000031:analogs & derivatives / Q000737:chemistry*; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects; D008830:Microbodies / Q000187:drug effects* / Q000201:enzymology; D010088:Oxidoreductases / Q000235:genetics; D051381:Rats; D018160:Receptors, Cytoplasmic and Nuclear / Q000235:genetics*; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D014157:Transcription Factors / Q000235:genetics*
D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors; D002995:Clofibric Acid; D010088:Oxidoreductases; D042962:Acyl-CoA Oxidase