title: [Intermittent prophylaxis in febrile seizures with oral diazepam: study of 82 cases].
abstract: We present our results of intermittent prophylaxis with oral diazepam in febrile seizures. We treated 82 patients aged between 3 months and 5 years. They have had simple or complex febrile seizures. Recurrence occurred in 22 patients (26%), none had a long-lasting febrile convulsion. Transient side effects occurred in 21.95% of the cases. We conclude that diazepam is a safe and effective drug for prophylaxis of febrile seizures when used as soon as any sign of illness appears. We suggest, however, that the administration of the drug should be indicated if the child presents at least one consistent predictor of risk of recurrent febrile seizures.
authors.affiliation: Departamento de Neurologia, Universidade Estadual de Campinas, Brasil.
authors.forename: M
authors.initials: M
authors.lastname: Costa
authors.forename: E A
authors.initials: EA
authors.lastname: Silva
authors.forename: A E
authors.initials: AE
authors.lastname: Silva
authors.forename: M M
authors.initials: MM
authors.lastname: Guerreiro
mesh_terms: D002675:Child, Preschool; D003975:Diazepam / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D012008:Recurrence; D012144:Respite Care; D012307:Risk Factors; D003294:Seizures, Febrile / Q000188:drug therapy*
chemical_list: D003975:Diazepam