title: What research with animals is telling us about alcohol-related neurodevelopmental disorder.
abstract: The substantial advances in understanding fetal alcohol syndrome over the past 20 years were made in large part because of research with animals. This review illustrates recent progress in animal research by focusing primarily on the central nervous system effects of prenatal alcohol exposure. Current findings suggest further progress in understanding consequences, risk factors, mechanisms, prevention and treatment will depend on continued research with animals.
authors.affiliation: Wayne State University School of Medicine, C.S. Mott Center for Human Growth and Development, Department of Obstetrics & Gynecology, Detroit, MI 48201, USA.
authors.forename: J H
authors.initials: JH
authors.lastname: Hannigan
mesh_terms: D000818:Animals; D002492:Central Nervous System Depressants / Q000633:toxicity*; D000431:Ethanol / Q000633:toxicity*; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000503:physiopathology*; D006801:Humans; D009420:Nervous System / Q000254:growth & development*; D009422:Nervous System Diseases / Q000139:chemically induced* / Q000503:physiopathology; D011247:Pregnancy; D013723:Teratogens / Q000633:toxicity*
chemical_list: D002492:Central Nervous System Depressants; D013723:Teratogens; D000431:Ethanol