Successful treatment of atypical mycobacterial meningitis by fluoroquinolone.
We report a case of restricted meningeal infection by atypical mycobacteria, identified by the polymerase chain reaction, in a non-immunocompromised adult successfully treated by multiple antibiotics including fluoroquinolone. New quinolones should be considered as a therapeutic option for such mycobacterial meningitis.
Komachi
H
H
Department of Neurology, Tokyo Medical and Dental University, Japan.
Uchihara
T
T
Saito
Y
Y
Takewaki
S
S
Nagai
R
R
Furukawa
T
T
D000284:Administration, Oral; D000328:Adult; D000583:Amikacin / Q000008:administration & dosage; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D000904:Antibiotics, Antitubercular / Q000008:administration & dosage; D000995:Antitubercular Agents / Q000008:administration & dosage; D003523:Cycloserine / Q000008:administration & dosage; D004977:Ethambutol / Q000008:administration & dosage; D006801:Humans; D007278:Injections, Spinal; D007538:Isoniazid / Q000008:administration & dosage; D008297:Male; D008581:Meningitis / Q000188:drug therapy* / Q000382:microbiology*; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy*; D015269:Mycobacterium avium Complex / Q000235:genetics / Q000302:isolation & purification*; D015242:Ofloxacin / Q000008:administration & dosage; D016133:Polymerase Chain Reaction; D012293:Rifampin / Q000008:administration & dosage; D013307:Streptomycin / Q000008:administration & dosage
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000904:Antibiotics, Antitubercular; D000995:Antitubercular Agents; D000583:Amikacin; D004977:Ethambutol; D003523:Cycloserine; D015242:Ofloxacin; D007538:Isoniazid; D012293:Rifampin; D013307:Streptomycin