[T3 hyperthyroidism with metastatic follicular thyroid carcinoma in substitution therapy].
This case report shows the anamnesis of a female patient with follicular Thyroidglandular-Ca. in an advanced stage with multiple metastases in the skeletal system, lungs and hilar lymph nodes. In addition, the patient showed a T3 hyperthyroidism with clinical symptoms but normal to low level of T4. After exclusion of hormone producing metastases as a reason for the hyperthyroidism, the most likely explanation would be an increased 5'-deiodination from T4 to T3.
Lang
M
M
Orthopädischen Universitätsklinik, Abt. Orthopädie II, Heidelberg, Deutschland.
Flesch
M
M
D018263:Adenocarcinoma, Follicular / Q000097:blood / Q000000981:diagnostic imaging / Q000473:pathology*; D000328:Adult; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood / Q000000981:diagnostic imaging / Q000209:etiology*; D007457:Iodine Radioisotopes; D008207:Lymphatic Metastasis; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011859:Radiography; D011877:Radionuclide Imaging; D013954:Thyroglobulin / Q000032:analysis; D013964:Thyroid Neoplasms / Q000097:blood / Q000000981:diagnostic imaging / Q000473:pathology*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood*
D007457:Iodine Radioisotopes; D014284:Triiodothyronine; D013972:Thyrotropin; D013954:Thyroglobulin; D013974:Thyroxine