Speculations on the mechanism of hormone-receptor interactions of the secretin/glucagon family of polypeptide hormones derived from computational structural studies.
Momany
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Tulane University Medical Center, New Orleans, Louisiana 70112, USA. frank@tulaneendo.tmc.tulane.edu
Bowers
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D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D003198:Computer Simulation; D005934:Glucagon / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D008961:Models, Structural; D008969:Molecular Sequence Data; D009479:Neuropeptides / Q000737:chemistry* / Q000378:metabolism; D018377:Neurotransmitter Agents / Q000737:chemistry; D051219:Pituitary Adenylate Cyclase-Activating Polypeptide; D017433:Protein Structure, Secondary; D011956:Receptors, Cell Surface / Q000737:chemistry* / Q000378:metabolism; D043562:Receptors, G-Protein-Coupled; D011964:Receptors, Gastrointestinal Hormone / Q000737:chemistry* / Q000378:metabolism; D018027:Receptors, Glucagon / Q000737:chemistry* / Q000378:metabolism; D012633:Secretin / Q000737:chemistry* / Q000378:metabolism; D014660:Vasoactive Intestinal Peptide / Q000737:chemistry* / Q000378:metabolism
C495401:ADCYAP1 protein, human; D009479:Neuropeptides; D018377:Neurotransmitter Agents; D051219:Pituitary Adenylate Cyclase-Activating Polypeptide; D011956:Receptors, Cell Surface; D043562:Receptors, G-Protein-Coupled; D011964:Receptors, Gastrointestinal Hormone; D018027:Receptors, Glucagon; C029937:secretin receptor; D012633:Secretin; D014660:Vasoactive Intestinal Peptide; D005934:Glucagon