title: [Constructing the reference panel of sera with standard level of IgG-antibodies].
abstract: Fundamentals of designing reference panels of sera for effective control of commercial test systems and immunoblotting, intended for detecting antiviral antibodies, have been developed. Reference low-titer panels of anti-IgG antibodies to HIV-a and hepatitis C virus have been designed. A reference panel contains diluted reactive sera with a standard level of IgG antibodies and native sera with undetectable level of antibodies to the major viral antigens from risk group subjects. The reactive sera of a panel contain the whole spectrum of antibodies to all principal viral antigens.
authors.forename: A N
authors.initials: AN
authors.lastname: Kanev
authors.forename: M S
authors.initials: MS
authors.lastname: Vorob'eva
authors.forename: N V
authors.initials: NV
authors.lastname: Shalunova
authors.forename: L A
authors.initials: LA
authors.lastname: Pereboeva
authors.forename: A Z
authors.initials: AZ
authors.lastname: Maksiutov
authors.forename: N N
authors.initials: NN
authors.lastname: Kiselev
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Shalaev
authors.forename: O N
authors.initials: ON
authors.lastname: Iastrebova
authors.forename: N A
authors.initials: NA
authors.lastname: Varaksin
mesh_terms: D006678:HIV / Q000276:immunology; D006526:Hepatitis C / Q000276:immunology; D006801:Humans; D007106:Immune Sera; D007074:Immunoglobulin G; D012015:Reference Standards
chemical_list: D007106:Immune Sera; D007074:Immunoglobulin G