Plasma fibrinogen in Israeli Moslem and Jewish school-children: distribution and relation to other cardiovascular risk factors. The Petah Tikva project.
Plasma fibrinogen levels were measured in 1,175 Israeli schoolchildren, aged 9-18 years, originating from diverse ethnic groups. The Moslem children displayed striking differences in levels and age-patterns of fibrinogen compared to Jewish children. Lower mean plasma fibrinogen levels in boys aged 9-10, 13-14 and 16-18 were observed among Moslem boys, compared to their Jewish counterparts born in Israel. Moslem girls showed lower levels of fibrinogen than Jewish Israeli girls at ages 9-10 and 16-18. While the Jewish children displayed an age-associated fibrinogen pattern comparable at the three age groups, the levels for Moslem children increased pre-puberty and decreased post-puberty, peaking at 13-14 years. No significant difference in mean plasma fibrinogen was found between sexes within ethnic groups. A number of statistically significant but low correlations (-0.32 to 0.24) were found between plasma fibrinogen and high density lipoprotein cholesterol (HDL-C) as a percentage of total cholesterol, triglycerides, blood glucose, uric acid, blood pressure, Quetelet index and sports activity. The difference between fibrinogen levels might point to a possible ethnicity risk factor explanation rather than environmentally acquired factors.
Zahavi
I
I
Department of Medicine C and Cardiology Service, Rabin Medical Center, Petah Tikva, Israel.
Yaari
S
S
Salman
H
H
Creter
D
D
Rudnicki
C
C
Brandis
S
S
Ferrara
M
M
Marom
R
R
Katz
M
M
Caneti
M
M
Hart
J
J
Goldbourt
U
U
D000293:Adolescent; D017677:Age Distribution; D001794:Blood Pressure; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000208:ethnology*; D002648:Child; D008076:Cholesterol, HDL / Q000097:blood; D003430:Cross-Sectional Studies; D005260:Female; D005340:Fibrinogen / Q000378:metabolism*; D006801:Humans; D007514:Islam; D007557:Israel; D007585:Jews; D008297:Male; D012307:Risk Factors; D017678:Sex Distribution; D013334:Students
D008076:Cholesterol, HDL; D005340:Fibrinogen