title: [The T-cell receptor--its participation in the pathological immune response].
abstract: This work reviews clonal rearrangements of T-cell receptor genes in peripheral T-cells of patients with lymphoproliferative diseases. The role of T-cell genes for predisposition to autoimmune diseases is analysed. Methodological approaches for analysis of T-cell receptor repertoire and autoimmune diseases are presented. The role of T-cell receptor-antigen recognitions in IgE mediated allergic reactions is described.
authors.forename: B
authors.initials: B
authors.lastname: Bozhkov
mesh_terms: D000937:Antigen-Antibody Reactions / Q000235:genetics / Q000276:immunology*; D001327:Autoimmune Diseases / Q000235:genetics / Q000276:immunology; D006801:Humans; D006967:Hypersensitivity / Q000235:genetics / Q000276:immunology; D008232:Lymphoproliferative Disorders / Q000235:genetics / Q000276:immunology; D011948:Receptors, Antigen, T-Cell / Q000235:genetics / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology; D009626:Terminology as Topic
chemical_list: D011948:Receptors, Antigen, T-Cell