title: Prevalence of lens opacities in the Barbados Eye Study.
abstract: OBJECTIVE
  To present population-based data on type and extent of age-related lens opacities in the predominantly black population of the Barbados Eye Study.
  
  
  METHODS
  Prevalence study.
  
  
  METHODS
  The Barbados Eye Study included 4709 participants (84% of those eligible), who were identified from a random sample of Barbadian-born citizens aged 40 to 84 years.
  
  
  METHODS
  Lens gradings at the slit lamp, obtained with the use of the Lens Opacities Classification System II.
  
  
  METHODS
  Prevalence of posterior subcapsular, nuclear, and cortical opacities (defined as a grade > or = 2 in either eye), as well as prevalence of any lens changes (including history of previous cataract surgery and/or cataract too advanced to grade).
  
  
  RESULTS
  Overall, 41% of the Barbados Eye Study population had any lens changes, including 3% with aphakia or an intraocular lens. Among the population of African descent, cortical opacities (34%) were most prevalent, followed by nuclear (19%) and posterior subcapsular (4%) opacities. Prevalence of all opacity types increased with age (P < .001). Cortical and nuclear opacities were more frequent in women than men. When prevalence of a single kind of opacity was considered, 21% of participants had cortical only, 6% had nuclear only, and 0.4% had posterior subcapsular only; 13% had mixed opacities. Visual acuity loss to worse than 20/40 in the more affected eye was present in 48%, 26%, and 18% of nuclear only, posterior subcapsular only, and cortical only types, respectively, and in 53% of mixed opacities.
  
  
  CONCLUSIONS
  The Barbados Eye Study provides the first prevalence data on different types of lens opacities in a large, predominantly black population. Whereas nuclear opacities are most common in white populations, cortical opacities were the most frequent type in the Barbados Eye Study, a finding of possible etiologic relevance. Other results highlight a higher frequency of opacities in women than men and a high prevalence of visual acuity loss in affected eyes.
authors.affiliation: University Medical Center at Stony Brook, NY, USA.
authors.forename: M C
authors.initials: MC
authors.lastname: Leske
authors.forename: A M
authors.initials: AM
authors.lastname: Connell
authors.forename: S Y
authors.initials: SY
authors.lastname: Wu
authors.forename: L
authors.initials: L
authors.lastname: Hyman
authors.forename: A
authors.initials: A
authors.lastname: Schachat
mesh_terms: D000328:Adult; D001741:Black or African American; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D001460:Barbados / Q000453:epidemiology; D002386:Cataract / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D006801:Humans; D007908:Lens, Crystalline / Q000473:pathology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011897:Random Allocation; D017678:Sex Distribution; D014792:Visual Acuity