title: Aggressive bone destruction in acute megakaryocytic leukemia: a rare presentation.
abstract: Acute megakaryocytic leukemia (AMKL) is a rare subtype of acute myeloid leukemia which is more common in children. Although the bone changes in leukemia are well documented, there are only a few reports of the AMKL subtype. We present an exceptional case of a young girl with very aggressive AMKL, who demonstrated symmetrical destructive lesions of the long bones characteristic of this disease. Lytic lesions of the skull and jaws were also present, and these have not been previously described in AMKL.
authors.affiliation: Department of Radiology, Shaare Zedek Medical Center, Hebrew University Medical School, P. O. Box 3235, Jerusalem, Israel.
authors.forename: D
authors.initials: D
authors.lastname: Fisher
authors.forename: R
authors.initials: R
authors.lastname: Ruchlemer
authors.forename: N
authors.initials: N
authors.lastname: Hiller
authors.forename: G
authors.initials: G
authors.lastname: Blinder
authors.forename: A
authors.initials: A
authors.lastname: Abrahamov
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D007223:Infant; D007947:Leukemia, Megakaryoblastic, Acute / Q000150:complications*; D010014:Osteolysis / Q000150:complications / Q000000981:diagnostic imaging*; D011859:Radiography