title: [The effect of the implantation of the human apo A-I gene on the function of the hepatocyte plasma membrane in rats].
abstract: Evidences are given that implantation of human apo A-I gene to experimental animals induces essential changes in the functional state of hepatocyte plasmatic phospholipid composition, hyperpolarization development, as well as changes in the Na, K-ATPase and adenylate cyclase activities. The presence of generalized cell reaction is evidenced from the fact than biosynthesis of summary proteins gets enhanced during the above changes.
authors.forename: V V
authors.initials: VV
authors.lastname: Frol'kis
authors.forename: V A
authors.initials: VA
authors.lastname: Kordium
authors.forename: S N
authors.initials: SN
authors.lastname: Novikova
authors.forename: D V
authors.initials: DV
authors.lastname: Irodov
authors.forename: O K
authors.initials: OK
authors.lastname: Kul'chitskiĭ
authors.forename: V E
authors.initials: VE
authors.lastname: Sabko
authors.forename: A L
authors.initials: AL
authors.lastname: Kobzar'
authors.forename: R I
authors.initials: RI
authors.lastname: Potapenko
authors.forename: L N
authors.initials: LN
authors.lastname: Bogatskaia
authors.forename: Kh K
authors.initials: KhK
authors.lastname: Muradian
mesh_terms: D000262:Adenylyl Cyclases / Q000378:metabolism; D000818:Animals; D016632:Apolipoprotein A-I / Q000235:genetics*; D002462:Cell Membrane / Q000235:genetics / Q000378:metabolism; D005786:Gene Expression Regulation / Q000502:physiology*; D018014:Gene Transfer Techniques; D006801:Humans; D008081:Liposomes; D008099:Liver / Q000378:metabolism*; D008563:Membrane Lipids / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism; D013997:Time Factors
chemical_list: D016632:Apolipoprotein A-I; D008081:Liposomes; D008563:Membrane Lipids; D008565:Membrane Proteins; D000262:Adenylyl Cyclases; D000254:Sodium-Potassium-Exchanging ATPase