[The functional modulation of neutrophils in mice by humoral factors of the nonparenchymatous cells of the intact liver and under an immune influence].
Cultured nonparenchymatous liver cells of mice produce both thermostable and thermolabile factors to influence oxygen-dependent metabolism, degranulation and phagocytosis of neutrophils. The liver cells treated with normal xenogeneic antibodies (0.5 mg/ml) produce factors to increase neutrophil functional activation. Treatment of the liver cells with anti-liver antibodies (0.5 mg/ml) results in suppression of neutrophil activation, liver cells produce thermolabile factors to suppress neutrophil oxygen-dependent metabolism and phagocytosis.
Portnychenko
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AH
D000818:Animals; D000917:Antibody Formation / Q000502:physiology; D002478:Cells, Cultured; D008099:Liver / Q000166:cytology / Q000276:immunology*; D051379:Mice; D008808:Mice, Inbred CBA; D009504:Neutrophils / Q000187:drug effects / Q000502:physiology*; D010587:Phagocytosis / Q000187:drug effects / Q000502:physiology