title: Lung transplantation for alpha 1-antitrypsin deficiency emphysema.
abstract: Lung transplantation is an option for appropriately selected patients with end-stage emphysema caused by alpha 1-antitrypsin deficiency. The functional results have been excellent after single or bilateral lung transplantation, and the medium-term survival results have been good. However, the role of alpha 1-antitrypsin replacement therapy after lung transplantation remains uncertain, and further investigation is needed.
authors.affiliation: Lung Transplant Program, Washington University-Barnes Hospital, St. Louis, USA.
authors.forename: E P
authors.initials: EP
authors.lastname: Trulock
mesh_terms: D006801:Humans; D008173:Lung Diseases, Obstructive / Q000601:surgery; D016040:Lung Transplantation / Q000401:mortality / Q000706:statistics & numerical data; D011656:Pulmonary Emphysema / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D011994:Recombinant Proteins / Q000627:therapeutic use; D012042:Registries; D012129:Respiratory Function Tests; D015996:Survival Rate; D014481:United States; D000515:alpha 1-Antitrypsin / Q000096:biosynthesis / Q000627:therapeutic use; D019896:alpha 1-Antitrypsin Deficiency
chemical_list: D011994:Recombinant Proteins; D000515:alpha 1-Antitrypsin