title: Central serous chorioretinopathy in younger and older adults.
abstract: OBJECTIVE
  The purpose of the study is to investigate the demographic characteristics and clinical findings of central serous chorioretinopathy (CSC).
  
  
  METHODS
  This study examined a consecutive series of 130 patients with CSC seen over an 18-month period.
  
  
  RESULTS
  The mean age of the patients when examined was 51 years, and the male-to-female ratio was 2.6:1.0. A total of 62 patients were older than 50 years of age when first examined. Although the patients shared some clinical and angiographic similarities, the older patients had a lower mean visual acuity and were more likely to have diffuse retinal pigment epitheliopathy, bilateral involvement, and secondary choroidal neovascularization than were the younger patients. With ophthalmoscopic and angiographic examination results, it was possible to differentiate CSC in older adults from choroidal neovascularization.
  
  
  CONCLUSIONS
  This study expands the clinical concept of CSC. The male-to-female ratio was much lower, and the range of ages of the patients was much greater than in previous studies. Disease manifestations in older adults differed somewhat from those seen in younger adults. In older patients, CSC can be distinguished from other exudative maculopathies, particularly that of choroidal neovascularization secondary to age-related macular degeneration.
authors.affiliation: LuEsther Mertz Retina Research Laboratory, New York, NY, USA.
authors.forename: R F
authors.initials: RF
authors.lastname: Spaide
authors.forename: L
authors.initials: L
authors.lastname: Campeas
authors.forename: A
authors.initials: A
authors.lastname: Haas
authors.forename: L A
authors.initials: LA
authors.lastname: Yannuzzi
authors.forename: Y L
authors.initials: YL
authors.lastname: Fisher
authors.forename: D R
authors.initials: DR
authors.lastname: Guyer
authors.forename: J S
authors.initials: JS
authors.lastname: Slakter
authors.forename: J A
authors.initials: JA
authors.lastname: Sorenson
authors.forename: D A
authors.initials: DA
authors.lastname: Orlock
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002829:Choroid / Q000098:blood supply / Q000473:pathology; D015862:Choroid Diseases / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005122:Exudates and Transudates; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000175:diagnosis; D012164:Retinal Diseases / Q000175:diagnosis*; D012189:Retrospective Studies; D017678:Sex Distribution; D014792:Visual Acuity