[The study of protective properties of attenuated strain of Argentinian hemorrhagic fever].
Immunization of BALB/c, C57BL/6, CBA/calac mice with strain XJ44 of Argentine hemorrhagic fever resulted in changes of nonspecific immunity parameters, such as interferon, interleukin-1, tumor necrosis factor, and natural killers. The formation of a specific humoral and cellular immune response in BALB/c mice immunized with this strain has been demonstrated. Immunization of BALB/c mice with strain XJ44 protected the animals from infection with a heterogeneous strain Carvallo of Bolivian hemorrhagic fever.
Ignat'ev
G M
GM
Blinov
V M
VM
Romanowski
V
V
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D006477:Arenaviruses, New World / Q000276:immunology*; D003429:Cross Reactions; D006478:Hemorrhagic Fever, American / Q000276:immunology / Q000517:prevention & control*; D007113:Immunity, Innate; D051379:Mice; D008807:Mice, Inbred BALB C; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009500:Neutralization Tests; D014613:Vaccines, Attenuated / Q000627:therapeutic use*; D014765:Viral Vaccines / Q000627:therapeutic use*
D000914:Antibodies, Viral; D014613:Vaccines, Attenuated; D014765:Viral Vaccines