Synergistic activation of the hydratase but not the ApoA1 gene by gemfibrozil and retinoids.
Mukherjee
R
R
Ligand Pharmaceuticals Inc., San Diego, California 92121, USA.
Jow
L
L
Strasser
J
J
Syka
P
P
Rosen
J
J
Heyman
R
R
D000154:Aconitate Hydratase / Q000235:genetics*; D000818:Animals; D016632:Apolipoprotein A-I / Q000235:genetics*; D000077610:Bexarotene; D004357:Drug Synergism; D015248:Gemfibrozil / Q000008:administration & dosage*; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D018160:Receptors, Cytoplasmic and Nuclear / Q000502:physiology; D012176:Retinoids / Q000008:administration & dosage*; D013764:Tetrahydronaphthalenes / Q000494:pharmacology; D014157:Transcription Factors / Q000502:physiology
D016632:Apolipoprotein A-I; D018160:Receptors, Cytoplasmic and Nuclear; D012176:Retinoids; D013764:Tetrahydronaphthalenes; D014157:Transcription Factors; D000077610:Bexarotene; D000154:Aconitate Hydratase; D015248:Gemfibrozil