The association of the Epstein-Barr virus with malignant lymphoma.
The Epstein-Barr virus, a human herpesvirus, has been found in the neoplastic cells of numerous lymphoid malignancies, including Burkitt's lymphoma, immunodeficiency-associated lymphoproliferative disorders, nasal T/NK lymphoma, and Hodgkin's disease. The available data suggest that Epstein-Barr virus contributes to the pathogenesis of many of these neoplasms but is not directly linked to the etiology of any of these lymphomas.
Chang
K L
KL
Division of Pathology, City of Hope National Medical Center, Duarte, CA 91010-0269, USA.
Weiss
L M
LM
D004854:Herpesvirus 4, Human / Q000472:pathogenicity; D006689:Hodgkin Disease / Q000821:virology*; D006801:Humans; D016393:Lymphoma, B-Cell / Q000821:virology*; D016399:Lymphoma, T-Cell / Q000821:virology*