title: Syntheses and pharmacological properties of new 2-aminobenzimidazole derivatives.
abstract: The paper reports the structures, syntheses and pharmacological properties of new compounds having a 2-aminobenzimidazole group. They exhibit various activities: histamine H1- and H2-receptors blocking activities, antilipidemic and platelet antiaggregatory, anti-inflammatory and analgesic properties, antimicrobial, fungicidal, parasiticide, antiarrythmic activity and muscle relaxant, comparable to those of drugs used in therapy.
authors.affiliation: Department of Technology of Drugs, Wroclaw University of Medicine, Poland.
authors.forename: W
authors.initials: W
authors.lastname: Nawrocka
mesh_terms: D000871:Anthelmintics / Q000138:chemical synthesis / Q000494:pharmacology; D000889:Anti-Arrhythmia Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis / Q000494:pharmacology; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D006634:Histamine H1 Antagonists / Q000138:chemical synthesis / Q000494:pharmacology; D006635:Histamine H2 Antagonists / Q000138:chemical synthesis / Q000494:pharmacology; D000960:Hypolipidemic Agents / Q000138:chemical synthesis / Q000494:pharmacology; D009125:Muscle Relaxants, Central / Q000138:chemical synthesis / Q000494:pharmacology
chemical_list: D000871:Anthelmintics; D000889:Anti-Arrhythmia Agents; D000890:Anti-Infective Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001562:Benzimidazoles; D006634:Histamine H1 Antagonists; D006635:Histamine H2 Antagonists; D000960:Hypolipidemic Agents; D009125:Muscle Relaxants, Central