[Gastric adenocarcinoma in hamartomatous polyp in Peutz-Jeghers syndrome].
The Peutz-Jeghers syndrome is characterized by gastrointestinal polyposis and mucocutaneous melanin pigmentation. Between the complications are the appearance of gastrointestinal neoplasms. There is an increasing evidence suggesting the hamartoma-adenoma-carcinoma sequence in Peutz-Jeghers syndrome. We present a 32-years-old man with Peutz-Jeghers syndrome who developed an adenocarcinoma arising in a gastric hamartomatous polyp. We discuss the risk to develop gastrointestinal neoplasms and the necessity for periodic surveillance.
Bujanda
L
L
Servicio de Digestivo, Hospital Nuestra Señora de Aránzazu, San Sebastián.
Beguiristain
A
A
Villar
J M
JM
Cosme
A
A
Castiella
A
A
Arriola
J A
JA
Arenas
J I
JI
D000230:Adenocarcinoma / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D000328:Adult; D001706:Biopsy; D005743:Gastrectomy; D005763:Gastroenterostomy; D006222:Hamartoma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007583:Jejunum / Q000601:surgery; D008207:Lymphatic Metastasis; D008297:Male; D010580:Peutz-Jeghers Syndrome / Q000150:complications*; D011127:Polyps / Q000150:complications* / Q000473:pathology / Q000601:surgery; D013270:Stomach / Q000473:pathology; D013274:Stomach Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery