title: Biochemical markers of coagulation activation in mitral stenosis, atrial fibrillation, and cardiomyopathy.
abstract: Advances in the understanding of the biochemistry of the mechanism of hemostasis have led to the development of sensitive methods for determining levels of markers which reflect thrombin activity (thrombin-antithrombin III complex, fibrinopeptide A, F1 + 2 fragment), active fibrinolysis (D-dimer, plasmin-alpha 2-plasmin inhibitor complex), and platelet activity (platelet factor 4, beta-thromboglobulin) in vivo. Measurement of these markers may be useful in identifying patients with various cardiovascular disorders at high risk of thromboembolism.
authors.affiliation: Department of Cardiology, Jichi Medical School, Tochigi, Japan.
authors.forename: U
authors.initials: U
authors.lastname: Ikeda
authors.forename: K
authors.initials: K
authors.lastname: Yamamoto
authors.forename: K
authors.initials: K
authors.lastname: Shimada
mesh_terms: D001281:Atrial Fibrillation / Q000097:blood*; D001777:Blood Coagulation; D001778:Blood Coagulation Disorders / Q000175:diagnosis*; D009202:Cardiomyopathies / Q000097:blood*; D006801:Humans; D008946:Mitral Valve Stenosis / Q000097:blood*; D015539:Platelet Activation