Escherichia coli positive regulator OmpR has a large loop structure at the putative RNA polymerase interaction site.
The C-terminal DNA-binding domain of OmpR, a positive regulator involved in osmoregulation expression of the ompF and ompC genes in Escherichia coli, has a helix-turn-helix variant motif. The 'turn' region, consisting of 11 residues, forms an RNA polymerase contact site.
Kondo
H
H
Nakagawa
A
A
Nishihira
J
J
Nishimura
Y
Y
Mizuno
T
T
Tanaka
I
I
D000595:Amino Acid Sequence; D001425:Bacterial Outer Membrane Proteins / Q000737:chemistry*; D001665:Binding Sites; D004268:DNA-Binding Proteins / Q000737:chemistry*; D012321:DNA-Directed RNA Polymerases / Q000737:chemistry*; D004926:Escherichia coli / Q000737:chemistry*; D019077:Helix-Turn-Helix Motifs; D008969:Molecular Sequence Data; D017433:Protein Structure, Secondary
D001425:Bacterial Outer Membrane Proteins; D004268:DNA-Binding Proteins; D012321:DNA-Directed RNA Polymerases