title: Excretion study of furazabol, an anabolic steroid, in human urine.
abstract: Furazabol and 16-hydroxyfurazabol represented the most abundant peaks in urinary metabolic profiles for two men obtained by gas chromatography-mass spectrometry (GC-MS) after oral administration of 5 mg furazabol. The excreted amounts of unchanged furazabol were determined and its response in GC-MS was compared with that of the 16-hydroxy metabolite. The maximum excretion rates of these compounds were reached 2-3 h after oral administration. The half-lives of unchanged furazabol for two human subjects, were 1.87 and 1.29 h respectively and the recovered amount in 48 h was 24% (33% for one, 15% for the other). Also the spectrum of an unidentified metabolite is reported.
authors.affiliation: Doping Control Center, Korea Institute of Science and Technology, Seoul, South Korea.
authors.forename: T
authors.initials: T
authors.lastname: Kim
authors.forename: J W
authors.initials: JW
authors.lastname: Suh
authors.forename: J C
authors.initials: JC
authors.lastname: Ryu
authors.forename: B C
authors.initials: BC
authors.lastname: Chung
authors.forename: J
authors.initials: J
authors.lastname: Park
mesh_terms: D000284:Administration, Oral; D045930:Anabolic Agents / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000652:urine*; D000732:Androstanols / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000652:urine*; D008401:Gas Chromatography-Mass Spectrometry; D006207:Half-Life; D006801:Humans; D008297:Male
chemical_list: D045930:Anabolic Agents; D000732:Androstanols; C005025:furazabol