[Comparative morphologic characteristics of viral hepatitis B and C].
Using liver biopsies in chronic HBV and HCV infections and their combination, the authors found between them morphological difference represented by nonspecific morphological markers. The combination of fat and hydropic hepatocytes degeneration, their heterogeneity, lymphoid follicles of various location and maturation degree, sinusoidal cell hyperplasia, accumulation of lymphocytes and macrophages in sinusoids, destruction, proliferation and sclerosis of ductules are of a high significance in hepatitis C. Etiological markers of hepatitis B are so-called ground-glass hepatocytes and "sand" nuclei. Various combination of these markers are characteristic for HBV and HCV co-infections with predominance among them of a replicating virus.
Serov
V V
VV
Severgina
L O
LO
Sekamova
S M
SM
Ignatova
T M
TM
Popova
I V
IV
Iusov
S P
SP
D015415:Biomarkers; D002908:Chronic Disease; D003937:Diagnosis, Differential; D006509:Hepatitis B / Q000150:complications / Q000276:immunology / Q000473:pathology*; D006526:Hepatitis C / Q000150:complications / Q000276:immunology / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000473:pathology; D014779:Virus Replication
D015415:Biomarkers