Impaired cholesterol synthesis rate in fibroblasts and reduced cellular uptake of LDLs derived from peroxisome-deficient patients cause cellular cholesterol deficiency in peroxisome-deficient fibroblasts.
Mandel
H
H
Department of Pediatrics, Rambam Medical Center Lipid Research Laboratory, Haifa, Israel.
Getsis
M
M
Rosenblat
M
M
Berant
M
M
Aviram
M
M
D002478:Cells, Cultured; D002784:Cholesterol / Q000096:biosynthesis*; D005347:Fibroblasts; D006801:Humans; D008077:Lipoproteins, LDL / Q000378:metabolism*; D008830:Microbodies / Q000378:metabolism*; D018901:Peroxisomal Disorders / Q000378:metabolism*; D012867:Skin
D008077:Lipoproteins, LDL; D002784:Cholesterol