title: SOX20, a new member of the SOX gene family, is located on chromosome 17p13.
abstract: SOX genes share a high sequence identity with the HMG box present in the testis determining gene SRY. We have identified a HMG box-like sequence motif on six contiguous cosmids, which cross-hybridize to a SOX9 cDNA probe. A data base search revealed a high similarity of the deduced amino acid sequence to the human SOX12 and the murine Sox16 HMG domains. The cosmids were assigned to chromosome 17p13 by FISH analysis.
authors.affiliation: Institute of Human Genetics, University of Freiburg, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Meyer
authors.forename: J
authors.initials: J
authors.lastname: Wirth
authors.forename: M
authors.initials: M
authors.lastname: Held
authors.forename: W
authors.initials: W
authors.lastname: Schempp
authors.forename: G
authors.initials: G
authors.lastname: Scherer
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D002886:Chromosomes, Human, Pair 17 / Q000235:genetics*; D004268:DNA-Binding Proteins / Q000235:genetics*; D006609:High Mobility Group Proteins / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D055747:SOX Transcription Factors
chemical_list: D004268:DNA-Binding Proteins; D006609:High Mobility Group Proteins; D055747:SOX Transcription Factors; C102810:SOX15 protein, human