title: [Effect of actual diet on fatty acid composition of blood serum and indicators of immunity in Siberian and Chukotka populations].
abstract: The spectra of blood fatty acids, the true diet and the immune system were explored in 40-54-aged male populations of Siberia and Chukotka. There were differences in the serum levels of omega 3, and omega 6-polyunsaturated fatty acids (PUFA) in the residents od the areas under study. The blood concentration of omega 3-PUFA was significantly higher in the Chukchi than that in Novosibirsk residents, which is associated with the fact the Chuchotka inhabitants consume sea fish and products, which are rich in eicosapentaenoic and docosahexaenic acids. Excess omega 3-PUFA was found to produce an immunosuppressive effect in the body: in the subjects having high serum omega 3-PUFA concentrations there was a reduced count of T lymphocyte, killer cells, responsible for cell-mediated immunity, as compared to those having low omega 3-PUFA concentrations.
authors.forename: A I
authors.initials: AI
authors.lastname: Rezvukhin
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Shalaurova
authors.forename: E V
authors.initials: EV
authors.lastname: Berezovskaia
mesh_terms: D000328:Adult; D000818:Animals; D004032:Diet; D015525:Fatty Acids, Omega-3 / Q000097:blood*; D043371:Fatty Acids, Omega-6; D005231:Fatty Acids, Unsaturated / Q000097:blood*; D005396:Fish Products; D005399:Fishes; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D008875:Middle Aged; D012800:Siberia
chemical_list: D015525:Fatty Acids, Omega-3; D043371:Fatty Acids, Omega-6; D005231:Fatty Acids, Unsaturated