Attention deficits in depression: an electrophysiological marker.
EVENT-RELATED POTENTIALS were recorded in young depressed subjects and compared with results from controls. Subjects were required to respond to targets (rare high-frequency sounds) presented to a designated ear, and to ignore targets presented to the non-designated ear as well as standards (frequent low-frequency sounds) presented to either ear. The results confirm those previously obtained with elderly depressed patients, showing the same general profile of electrophysiological and behavioural differences, and in particular a substantial reduction of the N200 amplitude in response to attended targets in depressed subjects. It is suggested that the N200 component could be a marker of depression.
el Massioui
F
F
LENA-CNRS URA-654, Université Pierre and Marie Curie, Paris VI, France.
Everett
J
J
Martin
M T
MT
Jouvent
R
R
Widlöcher
D
D
D000328:Adult; D001289:Attention Deficit Disorder with Hyperactivity / Q000503:physiopathology*; D015415:Biomarkers; D003866:Depressive Disorder / Q000503:physiopathology*; D005071:Evoked Potentials / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male
D015415:Biomarkers