title: Cervical pseudarthrosis in ankylosing spondylitis. A case report.
abstract: METHODS
  This report illustrates two different cases of cervical pseudarthrosis in ankylosing spondylitis.
  
  
  OBJECTIVE
  To point out the extreme rarity of this condition at cervical level, to discuss the pathogenesis, and to stress the necessity of surgical management.
  
  
  BACKGROUND
  Pathogenesis of pseudarthrosis in ankylosing spondylitis is discussed. Several factors are involved: trauma, which may be major or minor and undetected; stress fracture; and inflammatory changes. Major trauma was the cause of pseudarthrosis in the first patient, whereas stress fracture and inflammatory changes were the probable causes in patient 2. In patient 1 there were signs and symptoms of cord compression. Patient 2 was referred because of functional disability resulting from kyphosis and because of potential neurologic risk.
  
  
  METHODS
  Cervical fusion was performed in both patients. Patient 1 underwent posterior fusion; patient 2 had combined fusion. Patient 1 also underwent a lamineotomy.
  
  
  RESULTS
  The course of the disorder after surgery was uneventful in both patients. Neurologic symptoms subsided in patient 1; kyphosis was corrected in patient 2. Both patients resumed their preoperative activities. Follow-up evaluation was done 6 years after surgery in patient 1 and 2 years after surgery in patient 2.
  
  
  CONCLUSIONS
  Pseudarthrosis of the cervical spine in ankylosing spondylitis is extremely rare. Presentation of the two patients was different in terms of pathogenesis and signs and symptoms. Surgical treatment is advocated for this disorder.
authors.affiliation: Service of Orthopaedic Surgery, Höpital Beaujon, Clichy, France.
authors.forename: A
authors.initials: A
authors.lastname: Deburge
authors.forename: P
authors.initials: P
authors.lastname: Guigui
authors.forename: M
authors.initials: M
authors.lastname: Ouahes
authors.forename: E
authors.initials: E
authors.lastname: Barre
mesh_terms: D002574:Cervical Vertebrae / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009408:Nerve Compression Syndromes / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D011542:Pseudarthrosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D011859:Radiography; D013123:Spinal Fusion; D013167:Spondylitis, Ankylosing / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery