Emergence of high-level mupirocin resistance in methicillin-resistant Staphylococcus aureus isolated from Brazilian university hospitals.
Surveillance for methicillin-resistant Staphylococcus aureus (MRSA) was implemented in Rio de Janeiro and Uberlândia University Hospitals, which had different policies on use of mupirocin. One hundred fourteen multiresistant MRSA strains were isolated from 62 patients. Mupirocin resistance was observed in 63% of strains in Rio de Janeiro, where there was extensive use of topical mupirocin, and 6.1% in Uberlândia, where its use was rare.
Netto dos Santos
K R
KR
Universidade Federal do Rio de Janeiro, Instituto de Microbiologia, CCS, Brasil.
de Souza Fonseca
L
L
Gontijo Filho
P P
PP
D000900:Anti-Bacterial Agents; D001938:Brazil; D003428:Cross Infection / Q000188:drug therapy* / Q000382:microbiology; D004352:Drug Resistance, Microbial; D006785:Hospitals, University; D006801:Humans; D017053:Infection Control; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D016712:Mupirocin; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology; D013211:Staphylococcus aureus
D000900:Anti-Bacterial Agents; D016712:Mupirocin