title: Attention deficits in depression: an electrophysiological marker.
abstract: EVENT-RELATED POTENTIALS were recorded in young depressed subjects and compared with results from controls. Subjects were required to respond to targets (rare high-frequency sounds) presented to a designated ear, and to ignore targets presented to the non-designated ear as well as standards (frequent low-frequency sounds) presented to either ear. The results confirm those previously obtained with elderly depressed patients, showing the same general profile of electrophysiological and behavioural differences, and in particular a substantial reduction of the N200 amplitude in response to attended targets in depressed subjects. It is suggested that the N200 component could be a marker of depression.
authors.affiliation: LENA-CNRS URA-654, Université Pierre and Marie Curie, Paris VI, France.
authors.forename: F
authors.initials: F
authors.lastname: el Massioui
authors.forename: J
authors.initials: J
authors.lastname: Everett
authors.forename: M T
authors.initials: MT
authors.lastname: Martin
authors.forename: R
authors.initials: R
authors.lastname: Jouvent
authors.forename: D
authors.initials: D
authors.lastname: Widlöcher
mesh_terms: D000328:Adult; D001289:Attention Deficit Disorder with Hyperactivity / Q000503:physiopathology*; D015415:Biomarkers; D003866:Depressive Disorder / Q000503:physiopathology*; D005071:Evoked Potentials / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male
chemical_list: D015415:Biomarkers