Effect of prenatal alcohol and cigarette exposure on two- and six-month-old infants' adrenocortical reactivity to stress.
Examined the effect of prenatal alcohol and cigarette exposure on infant adrenocortical reactivity to stress at 2 and 6 months of age. Cortisol response (pre- to poststressor increase) at 2 months was lower for the exposed than nonexposed infants, whereas cortisol response at 6 months did not differ between the exposed and nonexposed infants. The 2-month group difference in cortisol response reflected a higher prestressor cortisol level in the exposed infants.
Ramsay
D S
DS
Institute for the Study of Child Development, Robert Wood Johnson Medical School, New Brunswick, New Jersey 08903-0019, USA.
Bendersky
M I
MI
Lewis
M
M
D000302:Adrenal Cortex / Q000503:physiopathology*; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D002658:Developmental Disabilities / Q000097:blood / Q000209:etiology / Q000503:physiopathology*; D000431:Ethanol; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D007223:Infant; D008297:Male; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D012907:Smoking; D013312:Stress, Physiological / Q000097:blood / Q000503:physiopathology*
D000431:Ethanol; D006854:Hydrocortisone