Pain elicited during intraoral infiltration with buffered lidocaine.
OBJECTIVE
To evaluate the effect of buffered lidocaine with self reporting of pain elicited during maxillary labial and palatal infiltrations of permanent canines.


METHODS
A standardized, prospective clinical trial of adult volunteers using a cross-over design of 20 paired injections using conventional 2% lidocaine with 1:100,000 epinephrine as the control.


RESULTS
Failed to establish a significant reduction in pain scores for either injection site when buffered lidocaine was injected intraorally.
Primosch
R E
RE
Department of Pediatric Dentistry, College of Dentistry, University of Florida, Gainesville 32610-0426, USA.
Robinson
L
L
D000328:Adult; D000704:Analysis of Variance; D000766:Anesthesia, Dental / Q000009:adverse effects / Q000379:methods*; D000779:Anesthetics, Local / Q000008:administration & dosage* / Q000009:adverse effects; D002021:Buffers; D018592:Cross-Over Studies; D004311:Double-Blind Method; D004338:Drug Combinations; D004837:Epinephrine / Q000008:administration & dosage; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007267:Injections / Q000009:adverse effects; D008012:Lidocaine / Q000008:administration & dosage* / Q000009:adverse effects; D010146:Pain / Q000209:etiology; D010147:Pain Measurement; D011446:Prospective Studies; D017693:Sodium Bicarbonate; D018709:Statistics, Nonparametric
D000779:Anesthetics, Local; D002021:Buffers; D004338:Drug Combinations; D017693:Sodium Bicarbonate; D008012:Lidocaine; D004837:Epinephrine