[The effect of gender on prevalence and survival in thyroid carcinoma].
Based on their own experience with a large group of patients with thyroid cancers, the authors confirm the higher prevalence of differentiated thyroid cancers both papillary and follicular (1 : 3,5) in females, while the differences in anaplastic and medullary cancers are much less prominent. Survival of females in univariate studies is much higher in both papillary and follicular cancers compared to males, in multivariate studies these differences lose their significance and only in papillary cancers under the age of 40 years at diagnosis and in a subgroup of papillofollicular cancers the differences retain their significance. The authors therefore deduce that differences found in univariate studies are significantly influenced by other factors such as age at the diagnosis and the spread of disease at the diagnosis.
Nĕmec
J
J
Klinika nukleární medicíny 2. LF UK, Praha Motol.
Chytrý
P
P
Dvorák
J
J
Vlcek
P
P
Neradilová
M
M
Racek
P
P
Blazek
T
T
Zeman
V
V
D018263:Adenocarcinoma, Follicular / Q000453:epidemiology / Q000401:mortality; D000328:Adult; D002277:Carcinoma / Q000453:epidemiology / Q000401:mortality; D018276:Carcinoma, Medullary / Q000453:epidemiology / Q000401:mortality; D002291:Carcinoma, Papillary / Q000453:epidemiology / Q000401:mortality; D018153:Czech Republic / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D015995:Prevalence; D012737:Sex Factors; D015996:Survival Rate; D013964:Thyroid Neoplasms / Q000453:epidemiology* / Q000401:mortality