[The clinico-immunological effects of T-activin in the combined treatment of patients with acute suppurative pyelonephritis].
Results were studied of use of T-activin in those clinical settings related to acute inflammatory diseases of the kidneys. There was a positive clinical effect from this preparation in all twenty-eight patients with acute purulent pyelonephritis, accompanied by readjustments in the patients' immune system. A rise to the norm was found to occur in T-helper counts, and accordingly, immunoregulatory index, NK-cell activity, blood microbocydic activity. The in vitro investigations done suggested the need for individual testing of immunocompetent cells of the patient to optimize the therapy.
Vozianov
A F
AF
Drannik
G N
GN
Pasechnikov
S P
SP
Driianskaia
V E
VE
Petrovskaia
I A
IA
Kushko
L Ia
LIa
Ozvinchuk
I I
II
Potrebinskiĭ
V M
VM
Milinevskiĭ
V A
VA
D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000917:Antibody Formation / Q000187:drug effects; D003131:Combined Modality Therapy; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007694:Killer Cells, Natural / Q000187:drug effects / Q000276:immunology; D018655:Lymphocyte Count / Q000187:drug effects; D010455:Peptides / Q000627:therapeutic use*; D011704:Pyelonephritis / Q000188:drug therapy* / Q000276:immunology; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology; D013949:Thymus Extracts / Q000627:therapeutic use*
D000276:Adjuvants, Immunologic; D010455:Peptides; D013949:Thymus Extracts; C036191:T-activin