title: Mechanism of action of topoisomerase II-targeted antineoplastic drugs.
authors.affiliation: Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37332-0146, USA.
authors.forename: N
authors.initials: N
authors.lastname: Osheroff
authors.forename: A H
authors.initials: AH
authors.lastname: Corbett
authors.forename: M J
authors.initials: MJ
authors.lastname: Robinson
mesh_terms: D000677:Amsacrine / Q000494:pharmacology; D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000494:pharmacology*; D004249:DNA Damage; D004250:DNA Topoisomerases, Type II / Q000502:physiology; D004273:DNA, Neoplasm / Q000187:drug effects*; D004317:Doxorubicin / Q000494:pharmacology; D024841:Fluoroquinolones; D006801:Humans; D008942:Mitoxantrone / Q000494:pharmacology; D059005:Topoisomerase II Inhibitors
chemical_list: D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D004273:DNA, Neoplasm; D024841:Fluoroquinolones; D059005:Topoisomerase II Inhibitors; D000677:Amsacrine; D004317:Doxorubicin; D008942:Mitoxantrone; D004250:DNA Topoisomerases, Type II