[The indices of the fibrinolysis, blood coagulation and lipid transport systems in hypertension patients].
Lipid spectrum, basal insulin concentration, the activity of coagulation factor VII and inhibitor of plasminogen tissue activator, content of plasminogen tissue activator antigen were assessed in 54 hypertensive patients with left ventricular hypertrophy (mean age 48.9 +/- 0.9 years, mean duration of the disease 15.7 +/- 1.1 years) after discontinuation of hypotensive therapy. A correlation was found between a rise in thrombogenic, atherogenic and a fall in fibrinolytic potential of blood. These findings suggest an essential role of insulin in regulation of thrombogenesis and fibrinolysis in hypertensive patients.
Sorokin
E V
EV
Karpov
Iu A
IuA
Dobrovol'skiĭ
A B
AB
Vil'chinskaia
M Iu
MIu
Panchenko
E P
EP
Titaeva
E V
EV
Kagan-Ponomarev
M Ia
MIa
D001692:Biological Transport; D001777:Blood Coagulation; D001795:Blood Pressure Determination; D004452:Echocardiography; D005260:Female; D005342:Fibrinolysis; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000175:diagnosis; D017379:Hypertrophy, Left Ventricular / Q000097:blood / Q000175:diagnosis; D007328:Insulin / Q000097:blood; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D015849:Plasminogen Inactivators / Q000097:blood; D010959:Tissue Plasminogen Activator / Q000097:blood
D007328:Insulin; D008055:Lipids; D015849:Plasminogen Inactivators; D010959:Tissue Plasminogen Activator