Tumor angiogenesis: functional similarities with tumor invasion.
In this review the functional relationship between tumor cell invasion and tumor-induced angiogenesis is discussed. Emphasis is placed on the similarities of the invasive phenotype in both processes and the common themes of alpha v beta 3 expression and gelatinase A activity.
Stetler-Stevenson
W G
WG
Extracellular Matrix Pathology Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.
Corcoran
M L
ML
D002448:Cell Adhesion; D002465:Cell Movement; D004730:Endothelium, Vascular / Q000503:physiopathology; D005109:Extracellular Matrix / Q000502:physiology; D006801:Humans; D008833:Microcirculation; D008954:Models, Biological; D009361:Neoplasm Invasiveness; D009369:Neoplasms / Q000098:blood supply* / Q000473:pathology*; D009389:Neovascularization, Pathologic