title: [Disorders in the interferon system in patients with virus-associated and chlamydial infections].
abstract: A more than 80% incidence of herpes simplex virus, cytomegalovirus, and chlamydial infection was revealed in 58 patients with various gynecological diseases. In 50% cases the infection was mixed. An appreciable reduction of the gamma-interferon system was detected in 20 patients, which was caused by a concomitant infectious process, possibly provoking the development of the underlying disease. Treatment of such patients should include antiviral and antichlamydial therapy, as well as correction of defects in interferon production.
authors.forename: F I
authors.initials: FI
authors.lastname: Ershov
authors.forename: L V
authors.initials: LV
authors.lastname: Antonova
authors.forename: S S
authors.initials: SS
authors.lastname: Grigorian
authors.forename: T G
authors.initials: TG
authors.lastname: Sukhikh
authors.forename: V N
authors.initials: VN
authors.lastname: Orlov
authors.forename: I B
authors.initials: IB
authors.lastname: Semenova
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Shmel'kov
mesh_terms: D000328:Adult; D002690:Chlamydia Infections / Q000150:complications / Q000378:metabolism*; D003586:Cytomegalovirus Infections / Q000150:complications / Q000378:metabolism*; D005260:Female; D006558:Herpes Genitalis / Q000150:complications / Q000378:metabolism*; D006561:Herpes Simplex / Q000150:complications / Q000378:metabolism*; D006801:Humans; D016898:Interferon-alpha / Q000096:biosynthesis; D007371:Interferon-gamma / Q000096:biosynthesis; D007372:Interferons / Q000096:biosynthesis*
chemical_list: D016898:Interferon-alpha; D007371:Interferon-gamma; D007372:Interferons