title: Regularized progressive expansion algorithm for recovery of scattering media from time-resolved data.
abstract: Reconstructions of the absorption cross sections of dense scattering media from time-resolved data are presented. A progressive expansion (PE) algorithm, similar to a layer-stripping, is developed to circumvent the underdeterminedness of the inverse problem. An overlapping scheme, which used detector readings from several consecutive time intervals, is introduced to reduce the propagation of reconstruction errors that occur at shallower depths. To reduce the sensitivity of the PE algorithm to noise a regularized progressive expansion (RPE) algorithm is proposed, which incorporates regularization techniques into the PE algorithm. The PE and the RPE algorithms are applied to the problem of image reconstruction from time-resolved data. The test media were isotropically scattering slabs containing one or two compact absorbers at different depths below the surface. The data were corrupted by additive white Gaussian noise with various strengths. The reconstruction results show that the PE and the RPE algorithms, when they are combined by proper overlapping, can effectively overcome the underdeterminedness of the inverse problem. The RPE algorithm yields reconstructions that are more accurate and more stable under the same noise level.
authors.affiliation: Department of Pathology, State University of New York Health Science Center, Brooklyn 11203, USA.
authors.forename: J
authors.initials: J
authors.lastname: Chang
authors.forename: W
authors.initials: W
authors.lastname: Zhu
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.forename: H L
authors.initials: HL
authors.lastname: Graber
authors.forename: R L
authors.initials: RL
authors.lastname: Barbour
mesh_terms: D000465:Algorithms; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008027:Light; D012542:Scattering, Radiation; D012996:Solutions; D014054:Tomography / Q000379:methods
chemical_list: D012996:Solutions