title: Effect of gallium nitrate therapy on Ga-67 scintigraphic detection of lymphoma: case report.
abstract: Ga-67 and abdominal CT scans of a 72-year-old woman who had malignant lymphoma before, during, and after gallium nitrate/hydroxyurea combination therapy are presented. Disappearance of Ga-67 uptake by the tumor during this treatment despite continuing CT evidence of disease and reappearance of Ga-67 scan abnormalities after cessation of therapy suggests that caution should be exercised when interpreting results of Ga-67 scintigraphy for the detection of tumor viability during gallium nitrate/hydroxyurea therapy.
authors.affiliation: Department of Radiology, Medical College of Wisconsin, Milwaukee 53226, USA.
authors.forename: G
authors.initials: G
authors.lastname: Akansel
authors.forename: Y
authors.initials: Y
authors.lastname: Liu
authors.forename: C R
authors.initials: CR
authors.lastname: Chitambar
authors.forename: M T
authors.initials: MT
authors.lastname: Kitapci
authors.forename: S
authors.initials: S
authors.lastname: Akansel
authors.forename: A Z
authors.initials: AZ
authors.lastname: Krasnow
authors.forename: A T
authors.initials: AT
authors.lastname: Isitman
authors.forename: B D
authors.initials: BD
authors.lastname: Collier
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005260:Female; D005708:Gallium / Q000008:administration & dosage / Q000627:therapeutic use*; D005710:Gallium Radioisotopes; D006801:Humans; D006918:Hydroxyurea / Q000008:administration & dosage / Q000627:therapeutic use*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D011877:Radionuclide Imaging; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents; D005710:Gallium Radioisotopes; D005708:Gallium; C027235:gallium nitrate; D006918:Hydroxyurea