The nature of autoantigens targeted in autoimmune endocrine diseases.
Autoimmune endocrine diseases result from autoimmune processes involving autoreactive T cells and/or autoantibodies. Considerable progress has been made in elucidating the self- (auto-) antigens involved in these processes. These include tissue-specific membrane receptors, enzymes and secreted hormones. As discussed here by Yao-Hua Song and colleagues, diagnostic and therapeutic applications should now result from these discoveries.
Song
Y H
YH
Dept of Pathology and Laboratory Medicine, University of Florida College of Medicine, Gainesville 32610, USA.
Li
Y
Y
Maclaren
N K
NK
D001323:Autoantibodies / Q000737:chemistry*; D001324:Autoantigens / Q000276:immunology*; D001327:Autoimmune Diseases / Q000276:immunology*; D004700:Endocrine System Diseases / Q000276:immunology*; D005260:Female; D006801:Humans
D001323:Autoantibodies; D001324:Autoantigens