title: Antibiotic phenol nor-triterpenes from Maytenus canariensis.
abstract: The new phenols 6-oxo-tingenol, 3-O-methyl-6-oxo-tingenol and 6-oxo-iguesterol were isolated from the root bark of Maytenus canariensis. Their structures were determined by 1H and 13C NMR spectroscopic studies, including HMQC, HMBC, DEPT and ROESY and chemical transformations. The synthesis of 6-oxo-tingenol was achieved from tingenone. These compounds exhibit antibiotic activity against Gram-positive bacteria.
authors.affiliation: Instituto Universitario de Bio-Orgánica Antonio González, Universidad de La Laguna, Tenerife, Canary Islands, Spain.
authors.forename: A G
authors.initials: AG
authors.lastname: González
authors.forename: N L
authors.initials: NL
authors.lastname: Alvarenga
authors.forename: A G
authors.initials: AG
authors.lastname: Ravelo
authors.forename: I A
authors.initials: IA
authors.lastname: Jiménez
authors.forename: I L
authors.initials: IL
authors.lastname: Bazzocchi
authors.forename: N J
authors.initials: NJ
authors.lastname: Canela
authors.forename: L M
authors.initials: LM
authors.lastname: Moujir
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification*; D002247:Carbon Isotopes; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D018517:Plant Roots / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D011522:Protons; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents; D002247:Carbon Isotopes; D011522:Protons; D013729:Terpenes