title: Enzymes and antibodies in organic media: analytical applications.
abstract: This chapter outlines the influence of organic solvents on antibodies, enzymes, and their reactions, the different kinds of enzyme-solvent systems and the various advantages of organic solvents compared with water, with respect to analytical purposes. Examples for electrochemical, optical and thermometric assays in organic solvents are given. The potential of organic solvents for the modification of immunoassays is exemplified, opening up new applications.
authors.affiliation: Institute of Biochemistry and Molecular Physiology, University of Potsdam, Max-Delbrück-Center of Molecular Medicine, Berlin, Germany.
authors.forename: W F
authors.initials: WF
authors.lastname: Stöcklein
authors.forename: F W
authors.initials: FW
authors.lastname: Scheller
mesh_terms: D000906:Antibodies / Q000378:metabolism*; D017151:Antibodies, Catalytic / Q000032:analysis; D004563:Electrochemistry; D004566:Electrodes; D004798:Enzymes / Q000378:metabolism*; D007118:Immunoassay; D012995:Solubility; D012997:Solvents / Q000145:classification / Q000494:pharmacology*
chemical_list: D000906:Antibodies; D017151:Antibodies, Catalytic; D004798:Enzymes; D012997:Solvents