title: Angiotensin I-converting enzyme inhibitors in autolysates of squid liver and mantle muscle.
abstract: Autolysis of squid liver and mantle muscle homogenates, and blends of both, each yielded inhibitory activity toward the angiotensin I-converting enzyme. The inhibitory activity and the amount of solubilized protein in each of these autolysates were examined over a period of 24 h. Inhibitory peptides were isolated from the mixed autolysate, their structures (IC50) being Tyr-Ala-Leu-Pro-His-Ala (9.8 microM) and Gly-Tyr-Ala-Leu-Pro-His-Ala (27.3 microM).
authors.affiliation: Laboratory of Food Technology, Hachinohe Institute of Technology, Aomori, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Wako
authors.forename: S
authors.initials: S
authors.lastname: Ishikawa
authors.forename: K
authors.initials: K
authors.lastname: Muramoto
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors / Q000302:isolation & purification*; D000818:Animals; D001329:Autolysis; D049832:Decapodiformes / Q000737:chemistry*; D008099:Liver / Q000737:chemistry*; D009132:Muscles / Q000737:chemistry*
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors