title: Yeast as a genetic model system for studying topoisomerase inhibitors.
authors.affiliation: Developmental Therapeutics Section, Childrens Hospital, Los Angeles, California, USA.
authors.forename: J L
authors.initials: JL
authors.lastname: Nitiss
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology*; D002166:Camptothecin / Q000494:pharmacology; D004260:DNA Repair; D004264:DNA Topoisomerases, Type I / Q000235:genetics; D004250:DNA Topoisomerases, Type II / Q000235:genetics; D004271:DNA, Fungal / Q000187:drug effects; D004351:Drug Resistance / Q000235:genetics; D008957:Models, Genetic; D009154:Mutation; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors; D015003:Yeasts / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics
chemical_list: D000970:Antineoplastic Agents; D004271:DNA, Fungal; D059004:Topoisomerase I Inhibitors; D059005:Topoisomerase II Inhibitors; D004264:DNA Topoisomerases, Type I; D004250:DNA Topoisomerases, Type II; D002166:Camptothecin