Synthesis of novel, aminoalkanolic derivatives of 5,7-dihydroxy-2-phenylbenzopyran-4-on as the potential cytostatic agents.
The 7-(2,3-epoxypropoxy)-2-phenyl-5-hydroxy-4H-benzopyran-4-on and its aminoalkanolic derivatives were prepared as the potential cytostatic (antileukemic) compounds. They were tested in vivo on mice leukemia L1210.
Mazur
A
A
Medical Academy of Warsaw, Department of Medical Chemistry, Poland.
Balicka
E
E
Zawadowski
T
T
Miks
B
B
Kawiak
J
J
D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D001578:Benzopyrans / Q000138:chemical synthesis* / Q000494:pharmacology; D005260:Female; D007939:Leukemia L1210 / Q000188:drug therapy*; D051379:Mice; D008815:Mice, Inbred Strains
D000970:Antineoplastic Agents; D001578:Benzopyrans