title: Salivary factors in children with recurrent parotitis. Part 2: Protein, albumin, amylase, IgA, lactoferrin lysozyme and kallikrein concentrations.
abstract: The concentrations of total protein, albumin, amylase, IgA, lactoferrin, lysozyme and kallikrein in parotid saliva from 17 children with juvenile recurrent parotitis (JRP) in a non-active phase of disease and in healthy controls of the same number, sex and age were analysed after gustatory stimulation with 1%, 2% and 6% citric acid. There was a great individual variation in all analysed variables, especially in saliva from the diseased glands. Significantly raised levels of albumin, IgA, lactoferrin and kallikrein were found in the saliva from the JRP-children compared with the controls (p < 0.01-0.001), while total protein and alpha-amylase did not differ significantly. The sialo-chemical findings are discussed in the light of histological and bacteriological findings and support the hypothesis that the etiology of juvenile recurrent parotitis is a combination of congenital malformation of portions of the salivary ducts and a set-in infection.
authors.affiliation: Institute for Postgraduate Dental Education, Jönköping, Sweden.
authors.forename: S
authors.initials: S
authors.lastname: Ericson
authors.forename: I
authors.initials: I
authors.lastname: Sjöbäck
mesh_terms: D000293:Adolescent; D000418:Albumins / Q000032:analysis; D000681:Amylases / Q000032:analysis; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D019343:Citric Acid; D005260:Female; D006801:Humans; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D007610:Kallikreins / Q000032:analysis; D007781:Lactoferrin / Q000032:analysis; D008297:Male; D009113:Muramidase / Q000032:analysis; D010306:Parotid Gland / Q000378:metabolism; D010309:Parotitis / Q000378:metabolism* / Q000382:microbiology / Q000473:pathology; D012008:Recurrence; D012463:Saliva / Q000737:chemistry* / Q000201:enzymology / Q000276:immunology / Q000378:metabolism; D018987:Salivary Ducts / Q000473:pathology; D012471:Salivary Proteins and Peptides / Q000032:analysis*
chemical_list: D000418:Albumins; D007071:Immunoglobulin A, Secretory; D012471:Salivary Proteins and Peptides; D019343:Citric Acid; D000681:Amylases; D009113:Muramidase; D007610:Kallikreins; D007781:Lactoferrin