title: [Surgery of the breast: 100 years after Halsted].
abstract: In the early years of this century prevailing currents of medical opinion led to the imposition of surgery that was even more aggressive than the radical mastectomy proposed by Halsted to treat breast cancer. More recently breast conservation surgery has become established but is always accompanied by additional local treatment and often the option of systemic therapy. Studies conducted in Milan were the first to demonstrate that conservative surgery plus and adjuvant therapy such as radiotherapy is efficacious in treating small-size breast cancer. As the year 2000 approaches it has become clear that breast cancer is curable in a high proportion of cases and attention is turning to improving the aesthetic outcome of surgery, and to investigating biological and genetic factors that influence the disease.
authors.affiliation: Divisione di Senologia dell'Istituto Europeo di Oncologia, Milano.
authors.forename: U
authors.initials: U
authors.lastname: Veronesi
authors.forename: S
authors.initials: S
authors.lastname: Zurrida
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D015410:Mastectomy, Extended Radical; D015409:Mastectomy, Radical; D015412:Mastectomy, Segmental; D009364:Neoplasm Recurrence, Local; D011879:Radiotherapy Dosage