[Indications for only pancreatic transplantation in the treatment of diabetes].
As the safety of simultaneous transplantation of the kidney and pancreas worldwide as well as in this country is increasing, transplantation of the pancreas only in the treatment of diabetes is becoming a more real issue. Reflections pro and con are even more important as transplantation of the pancreas is not a life saving operation. Limiting factors are nephrotoxicity of cyclosporin and the hitherto not negligible morbidity after transplantation. Problems of indication involve evaluation of co-existing diabetic nephropathy and the objective evaluation of causes of neuroglycopenia. Transplantation of the pancreas alone may be indicated in type 1 diabetics who suffer from life threatening hypoglycaemia, not caused by external factors. The prerequisite is adequate renal function.
Bartos
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Centrum diabetologie a poruch výzivy, IKEM, Praha.
D001786:Blood Glucose / Q000032:analysis; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D016035:Pancreas Transplantation
D001786:Blood Glucose