Non-genotoxic hepatocarcinogenesis: suppression of apoptosis by peroxisome proliferators.
Roberts
R A
RA
Zeneca Central Toxicology Laboratory, Macclesfield, United Kingdom.
D000818:Animals; D000924:Anticholesteremic Agents / Q000633:toxicity; D017209:Apoptosis / Q000187:drug effects*; D002118:Calcium / Q000502:physiology; D017373:Cyproterone Acetate / Q000008:administration & dosage; D004247:DNA / Q000096:biosynthesis; D053938:DNA Fragmentation; D007295:Inositol Phosphates / Q000502:physiology; D008113:Liver Neoplasms / Q000139:chemically induced* / Q000473:pathology; D008114:Liver Neoplasms, Experimental / Q000139:chemically induced* / Q000473:pathology; D009255:Nafenopin / Q000008:administration & dosage; D011493:Protein Kinase C / Q000502:physiology; D011743:Pyrimidines / Q000494:pharmacology*; D016196:S Phase / Q000187:drug effects
D000924:Anticholesteremic Agents; D007295:Inositol Phosphates; D011743:Pyrimidines; D009255:Nafenopin; D017373:Cyproterone Acetate; C006253:pirinixic acid; D004247:DNA; D011493:Protein Kinase C; D002118:Calcium