title: Simultaneous carriage of Candida albicans strains from HIV-infected patients with oral candidiasis: multilocus enzyme electrophoresis analysis.
abstract: Genetic diversity of 160 Candida albicans isolates from the oral cavity of 16 HIV-infected adults prior to antifungal treatment was assessed using multilocus enzyme electrophoresis (10 C. albicans colonies were randomly chosen from each specimen culture). 20 electrophoretic types were distinguished from the analysis of 21 enzyme loci (10 were polymorphic). Five patients (31%) were found to be colonized by 2 or 3 genetically distinct strains. Nevertheless, in these five cases, one strain predominated (from 7 to 9 of the 10 colonies). Some HIV + patients with oral candidiasis appear to be simultaneously infected with several genetically different C. albicans strains before antifungal treatment.
authors.affiliation: Service de Maladies Infectieuses et Tropicales, Hôpital Gui de Chauliac, Centre Hospitalier Universitaire, Montpellier, France.
authors.forename: J
authors.initials: J
authors.lastname: Reynes
authors.forename: C
authors.initials: C
authors.lastname: Pujol
authors.forename: C
authors.initials: C
authors.lastname: Moreau
authors.forename: M
authors.initials: M
authors.lastname: Mallié
authors.forename: F
authors.initials: F
authors.lastname: Renaud
authors.forename: F
authors.initials: F
authors.lastname: Janbon
authors.forename: J M
authors.initials: JM
authors.lastname: Bastide
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology*; D000328:Adult; D000483:Alleles; D002176:Candida albicans / Q000201:enzymology* / Q000235:genetics* / Q000302:isolation & purification; D002180:Candidiasis, Oral / Q000150:complications* / Q000382:microbiology*; D004592:Electrophoresis, Starch Gel; D004798:Enzymes / Q000235:genetics / Q000302:isolation & purification; D005260:Female; D014644:Genetic Variation; D006801:Humans; D008297:Male
chemical_list: D004798:Enzymes