[The antioxidant effects of emoxipin in patients with iron-deficiency anemia].
A total of 78 female patients of child-bearing age with iron deficiency anemia (IDA) of varying genesis and degree of severity were examined for effectiveness of a synthetic antioxidant emoxypine in a combined treatment of IDA. IDA was found to be associated with activation of lipid peroxidation processes (LPO) and decrement in antioxidant defence of the body. Conventional antianemic therapy does not lead to normalization of parameters characterizing LPO. Incorporation into a complex therapy of a synthetic antioxidant emoxypine reduces activity of free-radical oxidation of lipids, which fact prevents the pathological process from progressing and leads to more rapid and lasting clinical remission.
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D000293:Adolescent; D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000097:blood / Q000188:drug therapy*; D000975:Antioxidants / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D008875:Middle Aged; D010847:Picolines / Q000627:therapeutic use*; D012074:Remission Induction
D000975:Antioxidants; D010847:Picolines; C009820:6-methyl-2-ethyl-3-hydroxypyridine