title: Thoracic aorta: comparison of gadolinium-enhanced three-dimensional MR angiography with conventional MR imaging.
abstract: OBJECTIVE
  To evaluate gadolinium-enhanced three-dimensional magnetic resonance (MR) angiography for thoracic aortic disease and to compare this technique with conventional thoracic MR imaging.
  
  
  METHODS
  One hundred eight consecutive patients underwent 122 thoracic MR examinations, including conventional MR imaging followed by enhanced three-dimensional MR angiography. A gradient-echo sequence was used at 1.5 T (116 examinations) and 1.0 T (6 examinations) during infusion of 0.2 mmol/kg gadopentetate dimeglumine. Two independent readers (A and B), with varied experience in thoracic MR angiography, retrospectively evaluated the images for presence of aortic dissection, aneurysm, arch vessel disease, and protruding atheroma. Correlation with findings of surgery or other imaging modalities was available in 98 cases.
  
  
  RESULTS
  Enhanced MR angiography was sensitive (92%-96%) and specific (100%) for acute and chronic aortic dissection (n = 26) and was as useful as conventional MR imaging in the diagnosis of aneurysm (n = 43) and arch vessel disease (n = 7). One of two intramural hematomas were overlooked at MR angiography by reader A, and both were overlooked by reader B.
  
  
  CONCLUSIONS
  Enhanced three-dimensional MR angiography is a rapid and accurate imaging modality in diagnosis of thoracic aortic disease but is insensitive to intramural hematoma.
authors.affiliation: Department of Radiology, New York University Medical Center, NY 10016, USA.
authors.forename: G A
authors.initials: GA
authors.lastname: Krinsky
authors.forename: N M
authors.initials: NM
authors.lastname: Rofsky
authors.forename: D R
authors.initials: DR
authors.lastname: DeCorato
authors.forename: J C
authors.initials: JC
authors.lastname: Weinreb
authors.forename: J P
authors.initials: JP
authors.lastname: Earls
authors.forename: M A
authors.initials: MA
authors.lastname: Flyer
authors.forename: A C
authors.initials: AC
authors.lastname: Galloway
authors.forename: S B
authors.initials: SB
authors.lastname: Colvin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000784:Aortic Dissection / Q000175:diagnosis; D001013:Aorta, Thoracic / Q000473:pathology*; D017545:Aortic Aneurysm, Thoracic / Q000175:diagnosis; D001017:Aortic Coarctation / Q000175:diagnosis; D001018:Aortic Diseases / Q000175:diagnosis*; D003287:Contrast Media; D004338:Drug Combinations; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007231:Infant, Newborn; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D008536:Meglumine; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives*; D012189:Retrospective Studies
chemical_list: D003287:Contrast Media; D004338:Drug Combinations; D009942:Organometallic Compounds; D008536:Meglumine; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA