title: Paraneoplastic syndromes associated with small cell lung cancer.
abstract: The term paraneoplastic syndrome refers to the ability of some tumors to produce signs and symptoms at a distance from the site of the primary tumor or its metastases. Paraneoplastic syndromes may develop before the diagnosis of carcinoma is made. Paraneoplastic syndromes associated with small cell lung cancer (SCLC) include endocrinologic abnormalities secondary to peptide hormone production, and neurologic sequelae due to autoantibody production. This article reviews the common paraneoplastic syndromes that may occur in patients with SCLC.
authors.affiliation: Department of Medicine, Veterans Affairs Medical Center, Syracuse, New York, USA.
authors.forename: C C
authors.initials: CC
authors.lastname: Marchioli
authors.forename: S L
authors.initials: SL
authors.lastname: Graziano
mesh_terms: D000182:ACTH Syndrome, Ectopic / Q000209:etiology; D009320:Atrial Natriuretic Factor / Q000502:physiology; D018288:Carcinoma, Small Cell / Q000150:complications*; D002526:Cerebellar Diseases / Q000209:etiology; D004679:Encephalomyelitis / Q000209:etiology; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000209:etiology; D015624:Lambert-Eaton Myasthenic Syndrome / Q000209:etiology; D008175:Lung Neoplasms / Q000150:complications*; D010257:Paraneoplastic Syndromes / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012164:Retinal Diseases / Q000209:etiology
chemical_list: D009320:Atrial Natriuretic Factor