New triterpenoid saponins from Gynostemma pentaphyllum.
Three new triterpenoidal saponins (1-3), together with the known compound 4, were isolated from a MeOH extract of the aerial parts of Gynostemma pentaphyllum. Their structures were elucidated on the basis of chemical and spectral methods, such as 1H-1H DQFCOSY, HMQC, HMBC, and TOCSY NMR spectra. The aglycon moiety of 1 and 2 is a new dammarane-type triterpene 12-oxo-2 alpha, 3 beta, 20 (S)-trihydroxydammar- 24-ene.
Hu
L
L
Shanghai Institute of Materia Medica, Academia Sinica, People's Republic of China.
Chen
Z
Z
Xie
Y
Y
D002240:Carbohydrate Sequence; D029774:Gynostemma / Q000737:chemistry*; D006868:Hydrolysis; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification*
D010936:Plant Extracts; D012503:Saponins; D014315:Triterpenes