Antibiotic prophylaxis in umbilical and incisional hernia repair: a prospective randomised study.
OBJECTIVE
To find out if preoperative prophylaxis would reduce infection rates after umbilical and incisional hernia repair.


METHODS
Randomised controlled trial.


METHODS
Teaching hospital, Israel.


METHODS
35 Patients who presented with umbilical (n = 19) or incisional (n = 16) hernias during a period of 8 months.


METHODS
Cefonicid 1 g was given by intravenous infusion to alternate patients 30 minutes before the operation.


METHODS
Wound infection.


RESULTS
The groups were comparable for age, body mass index, grade of surgeon, operating time, and size of hernial ring. The wound infection rates were 0/8 compared with 4/8 for incisional hernia repairs (p = 0.08) and 1/9 compared with 4/10 for umbilical hernia repairs (p = 0.3). The overall rate was 1/17 compared with 8/18 (p = 0.02).


CONCLUSIONS
Single dose antibiotic puphylaxis seems to exert a beneficial effect on the wound infection rate after umbilical and incisional hernia repair.
Abramov
D
D
Department of Surgery A and B, Shaare Zedek Medical Center, Jerusalem, Israel.
Jeroukhimov
I
I
Yinnon
A M
AM
Abramov
Y
Y
Avissar
E
E
Jerasy
Z
Z
Lernau
O
O
D000328:Adult; D019072:Antibiotic Prophylaxis; D015790:Cefonicid / Q000627:therapeutic use*; D002511:Cephalosporins / Q000627:therapeutic use*; D006554:Hernia, Umbilical / Q000601:surgery*; D006555:Hernia, Ventral / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D011300:Preoperative Care; D011446:Prospective Studies; D013530:Surgical Wound Infection / Q000517:prevention & control*; D016896:Treatment Outcome
D002511:Cephalosporins; D015790:Cefonicid