title: Is the response to rhGH in peritoneal dialysis patients less effective than in patients with chronic renal insufficiency.
abstract: Data on the effects of rhGH treatment in children on peritoneal dialysis are limited. In general rhGH therapy seems to be less effective compared with results on patients with chronic renal failure on conservative treatment. Our experience suggests that rhGH can stimulate growth in children on CPD, and that the efficacy of such therapy is reduced after the first year of treatment, although the rhGH is still active.
authors.affiliation: Department of Nephrology Dialysis and Transplantation, G Gaslini Children Institute, Genoa, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Perfumo
authors.forename: E
authors.initials: E
authors.lastname: Verrina
authors.forename: A
authors.initials: A
authors.lastname: Edefonti
authors.forename: A
authors.initials: A
authors.lastname: Trivelli
authors.forename: A
authors.initials: A
authors.lastname: Canepa
authors.forename: R
authors.initials: R
authors.lastname: Gusmano
mesh_terms: D002648:Child; D005260:Female; D006128:Growth / Q000187:drug effects; D006130:Growth Disorders / Q000188:drug therapy* / Q000209:etiology; D019382:Human Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000628:therapy; D008297:Male; D010530:Peritoneal Dialysis; D010531:Peritoneal Dialysis, Continuous Ambulatory
chemical_list: D019382:Human Growth Hormone