[Kallikrein-kinin indices and biological composition of exhaled condensate in acute bronchitis patients with varying disease course].
Parameters of blood kallikrein-kinin system (KKS) and biochemical composition of humor condensated from the exhaled air have been evaluated in 87 patients with acute bronchitis (36 cases with lingering course and 31 with recurrent). The progression of acute bronchitis is associated with elevated blood concentrations of acute-phase proteins, KKS activation in the blood and high serotonin and lactic acid content in the humor condensated from the exhaled air. Lingering and recurrent course of the disease are characterized by more pronounced reduction in inhibitory activity of kallikrein, in activity of angiotensin-converting enzyme and emergence of noradrenalin in high concentration.
Goncharova
V A
VA
State Scientific Center of Pulmonology, Saint-Petersburg.
Borisenko
L V
LV
Dotsenko
E K
EK
Pokhaznikova
M A
MA
D000208:Acute Disease; D000209:Acute-Phase Proteins / Q000502:physiology*; D000293:Adolescent; D000328:Adult; D001991:Bronchitis / Q000175:diagnosis / Q000503:physiopathology*; D018450:Disease Progression; D005260:Female; D006801:Humans; D016234:Kallikrein-Kinin System / Q000502:physiology*; D019344:Lactic Acid / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012119:Respiration / Q000502:physiology; D012701:Serotonin / Q000502:physiology
D000209:Acute-Phase Proteins; D012701:Serotonin; D019344:Lactic Acid