title: [Malformations of intranasal structures and rhinosinusitis in children].
abstract: 240 patients with acute and 233 children with chronic nasal and paranasal sinus disease aged under 14 years have undergone endoscopic examination. It was found that the number of serious developmental defects hindering drainage of the paranasal sinusis was higher in children with rhinogenic orbital complications than in those with acute sinusitis. Chronic affections of the nose and paranasal sinusis in most examinees were accompanied by malformations of the intranasal structures deteriorating mucociliary transport both in nasal cavity and paranasal sinusis. The occurrence of the above and septal defects increased with age. The conclusion is made that defects of the intranasal structures contribute significantly to the onset of acute sinusis (AS) in children, AS transformation into chronic form, emergence of complications along with general and local immunodeficiency, microbial virulence. The findings support the principal conception of sinusitis pathogenesis offered by W. Messerklinger which justifies early functional endoscopic operations in nasal cavity for prevention and treatment of nasal and paranasal diseases.
authors.affiliation: Department of LOR-Diseases, RGMU, Moscow.
authors.forename: T I
authors.initials: TI
authors.lastname: Garashchenko
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D009666:Nose / Q000002:abnormalities*; D012189:Retrospective Studies; D012220:Rhinitis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012852:Sinusitis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy