title: Lowered phosphorylation of topoisomerase I is a direct reason for reduced sensitivity of L5178Y-S cells to camptothecin.
authors.affiliation: Institute of Biochemistry, Warsaw University, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Staron
authors.forename: B
authors.initials: B
authors.lastname: Kowalska-Loth
authors.forename: I
authors.initials: I
authors.lastname: Szumiel
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology*; D002166:Camptothecin / Q000494:pharmacology*; D004264:DNA Topoisomerases, Type I / Q000378:metabolism*; D004351:Drug Resistance; D007940:Leukemia L5178 / Q000201:enzymology* / Q000473:pathology; D051379:Mice; D010766:Phosphorylation; D011064:Poly Adenosine Diphosphate Ribose / Q000378:metabolism; D014407:Tumor Cells, Cultured
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D011064:Poly Adenosine Diphosphate Ribose; D004264:DNA Topoisomerases, Type I; D002166:Camptothecin