Mutations within the CD4-CDR-3-like loop allow replication in an immortalized T cell line of HIV type 1 viruses chimeric for envelope glycoproteins containing non-syncytium-inducing V3 loops.
Signoret
N
N
de Jong
J
J
Goudsmit
J
J
Sattentau
Q J
QJ
D000595:Amino Acid Sequence; D015704:CD4 Antigens / Q000235:genetics*; D002460:Cell Line; D015726:Giant Cells / Q000821:virology; D015699:HIV Envelope Protein gp120 / Q000737:chemistry / Q000235:genetics* / Q000276:immunology; D015497:HIV-1 / Q000235:genetics / Q000276:immunology / Q000502:physiology*; D006801:Humans; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D010446:Peptide Fragments / Q000737:chemistry / Q000235:genetics* / Q000276:immunology; D016865:Reassortant Viruses / Q000235:genetics / Q000502:physiology; D013045:Species Specificity; D013601:T-Lymphocytes / Q000166:cytology / Q000821:virology*; D014779:Virus Replication
D015704:CD4 Antigens; D015699:HIV Envelope Protein gp120; C059762:HIV envelope protein gp120 (305-321); D010446:Peptide Fragments