title: Using yeast to understand drugs that target topoisomerases.
authors.affiliation: Molecular Pharmacology Department, St. Jude Children's Research Hospital, Memphis, Tennessee 38101, USA.
authors.forename: J L
authors.initials: JL
authors.lastname: Nitiss
authors.forename: A
authors.initials: A
authors.lastname: Rose
authors.forename: K C
authors.initials: KC
authors.lastname: Sykes
authors.forename: J
authors.initials: J
authors.lastname: Harris
authors.forename: J
authors.initials: J
authors.lastname: Zhou
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology; D002166:Camptothecin / Q000494:pharmacology; D004247:DNA / Q000187:drug effects; D004249:DNA Damage; D004264:DNA Topoisomerases, Type I / Q000187:drug effects* / Q000235:genetics; D004351:Drug Resistance / Q000235:genetics; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000201:enzymology* / Q000235:genetics; D059004:Topoisomerase I Inhibitors
chemical_list: D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D004791:Enzyme Inhibitors; D059004:Topoisomerase I Inhibitors; D004247:DNA; D004264:DNA Topoisomerases, Type I; D002166:Camptothecin