title: The use of two measures of health-related quality of life in HIV-infected individuals: a cross-sectional comparison.
abstract: Two measures of health-related quality of life in 65 HIV-infected individuals were compared in a cross-sectional design. The Quality of Well-Being Scale (QWB) results in a single score ranging from death to perfect health. The MOS-HIV Health Survey (MOS-HIV, 34-item version) gives scores in 11 dimensions. The QWB score distinguished subjects with AIDS from those who were asymptomatic (p = 0.027). For the seven multi-item scales of the MOS-HIV, Cronbach's alpha ranged from 0.85-0.95, indicating good internal consistency reliability. Clinical HIV-infection status was significantly associated with the dimensions of Overall Health (p = 0.002), Role Function (p = 0.022), Social Function (p = 0.037), Energy/Fatigue (p = 0.027) and Health Distress (p = 0.025). All eleven dimensions of the MOS-HIV were significantly correlated with the QWB score (Spearman's coefficient = 0.405-0.670; for all, p < 0.01) and the QWB score could be predicted from the MOS-HIV dimension scores using multiple regression. The QWB and the MOS-HIV may be useful in assessing health-related quality of life in patients infected with HIV.
authors.affiliation: Tucson Veterans Affairs Medical Center, University of Arizona Colleges of Medicine 85723, USA.
authors.forename: A E
authors.initials: AE
authors.lastname: Copfer
authors.forename: N M
authors.initials: NM
authors.lastname: Ampel
authors.forename: T E
authors.initials: TE
authors.lastname: Hughes
authors.forename: K J
authors.initials: KJ
authors.lastname: Gregor
authors.forename: C L
authors.initials: CL
authors.lastname: Dols
authors.forename: S J
authors.initials: SJ
authors.lastname: Coons
authors.forename: K
authors.initials: K
authors.lastname: Colgan
authors.forename: A W
authors.initials: AW
authors.lastname: Wu
mesh_terms: D000328:Adult; D001130:Arizona; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000523:psychology*; D006801:Humans; D016014:Linear Models; D008297:Male; D011594:Psychometrics; D011788:Quality of Life; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires