High-Resolution NMR Probe for Experiments at High Pressures
A 300 MHz high-resolution, high-pressure NMR probe which operates in the pressure range of 1 bar to 9 kbar at temperatures of -30 to 100&deg;C is described. Specialized novel design features of the probe are discussed and test spectra showing resolution better than 1 Hz (<3.0 x 10(-9)) for 8 mm samples are presented. Potential biochemical applications of this probe are illustrated by experiments dealing with the pressure-induced unfolding of hen egg white lysozyme.
Ballard
L
Department of Chemistry, University of Illinois, Urbana, Illinois, 61801
Reiner
C
Jonas
J