Apoptosis: does stress kill?
A wide variety of cellular stresses can initiate apoptosis, or programmed cell death. Recent work shows that the mechanism involves stress-activated protein kinase pathways, although the targets of these pathways are unknown at present.
Cosulich
S
S
School of Biological Sciences, Manchester, UK.
Clarke
P
P
D017209:Apoptosis / Q000502:physiology*; D017871:Calcium-Calmodulin-Dependent Protein Kinases / Q000378:metabolism*; D048031:JNK Mitogen-Activated Protein Kinases; D020928:Mitogen-Activated Protein Kinases; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism; D011518:Proto-Oncogene Proteins / Q000378:metabolism; D019908:Proto-Oncogene Proteins c-raf; D015398:Signal Transduction / Q000502:physiology*; D019014:fas Receptor / Q000378:metabolism; D018631:ras Proteins / Q000378:metabolism
D011518:Proto-Oncogene Proteins; D019014:fas Receptor; D017346:Protein Serine-Threonine Kinases; D019908:Proto-Oncogene Proteins c-raf; D017871:Calcium-Calmodulin-Dependent Protein Kinases; D048031:JNK Mitogen-Activated Protein Kinases; D020928:Mitogen-Activated Protein Kinases; D018631:ras Proteins