Multiple retiform hemangioendotheliomas. A low-grade angiosarcoma.
We present the case of a 30-year-old woman who over a 10-year period has developed multiple well-differentiated angiosarcomas involving the trunk and extremities. The clinical and histologic features are characteristic of retiform hemangioendothelioma (RH), a distinctive form of low-grade angiosarcoma. This case is unique in that multiple lesions developed in different anatomic sites. We discuss the clinical and histologic characteristics, diagnosis, and prognosis of RH.
Duke
D
D
Harvard Medical School, Boston, MA, USA.
Dvorak
A
A
Harris
T J
TJ
Cohen
L M
LM
D000328:Adult; D003094:Collagen; D003937:Diagnosis, Differential; D004730:Endothelium, Vascular / Q000473:pathology; D005260:Female; D006390:Hemangioendothelioma / Q000473:pathology*; D006394:Hemangiosarcoma / Q000145:classification / Q000473:pathology*; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D011379:Prognosis; D012598:Sclerosis; D012878:Skin Neoplasms / Q000145:classification / Q000473:pathology*
D003094:Collagen