Current diagnosis and treatment of central nervous system germ cell tumours.
Central nervous system germ cell tumours can be cured with high quality posttreatment neuropsychological and endocrinological measures. In order to firmly establish a histological diagnosis, surgery is essential. Management should be planned precisely according to histological and biological malignancy and the extent of the disease. Patients with germinoma can be cured by preirradiation chemotherapy followed by reduced dose irradiation.
Sawamura
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Department of Neurosurgery, University of Hokkaido School of Medicine, Sapporo, Japan.
D001921:Brain / Q000473:pathology; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D003399:Craniotomy; D006801:Humans; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D018714:Radiotherapy, Adjuvant; D016896:Treatment Outcome