[Optic nerve gliomas: a study of 11 cases].
Optic nerve gliomas may occur alone or as components of neurofibromatosis. They are rare tumors accounting for 2 to 5% of all intracranial tumors and 6% of the intra-orbitary neoplasms. The authors present 11 cases of optic nerve-glioma diagnosed in Curitiba in the last 25 years. Out of these 11 patients there were 10 women and only 1 man. The ages ranged from 3 to 25 years old, and 6 patients were under 15 years. In this series, 27.3% (n = 3) of the cases were associated with neurofibromatosis. Five patients had their tumors restricted to the optic nerve while the others had either extension to the optic chiasm, supra-selar region, frontal or temporal lobe. All the patients had pilocytic astrocytomas.
Torres
L F
LF
Seção de Microscopia Eletrônica e Neuropatologia, Universidade Federal do Paraná, Curitiba.
Medeiros
B C
BC
Noronha
L
L
Pedroso
A
A
Ramina
R
R
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003390:Cranial Nerve Neoplasms / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D005910:Glioma / Q000453:epidemiology* / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D015994:Incidence; D008297:Male; D009901:Optic Nerve Diseases / Q000453:epidemiology* / Q000473:pathology; D015995:Prevalence