title: Mass spectrometry in protein studies from genome to function.
abstract: The demands for highly sensitive and specific analytical techniques in biochemistry, molecular biology and biotechnology are met by new developments in mass spectrometry. Femto- to attomole sensitivity and mass accuracy in a low parts per million range can now be routinely obtained. Mass spectrometry, already accepted for studies of protein secondary modifications, must, in the future, be expected to be an important tool in protein studies on all levels, ranging from proteome analysis to studies of protein higher order structures and protein interaction.
authors.affiliation: Department of Molecular Biology, Odense University, DK 5230 Odense M, Denmark. roe@pr-group.ou.dk
authors.forename: P
authors.initials: P
authors.lastname: Roepstorff
mesh_terms: D001709:Biotechnology; D003001:Cloning, Molecular; D016678:Genome; D013058:Mass Spectrometry / Q000379:methods*; D015394:Molecular Structure; D017510:Protein Folding; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry* / Q000235:genetics / Q000502:physiology; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D011506:Proteins