Mitochondrial encephalomyopathy with elderly onset of stroke-like episodes.
A 52-year-old woman with a history of a hearing disturbance since age 20 experienced visual hallucinations and convulsions, followed by right hemiparesis and aphasia. On the basis of a muscle biopsy and mitochondrial DNA analysis, she was diagnosed as mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS). This case is unique in that the stroke-like episodes occurred 30 years after disease onset.
Minamoto
H
H
Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya.
Kawabata
K
K
Okuda
B
B
Shibuya
N
N
Tachibana
H
H
Sugita
M
M
Goto
Y
Y
Nishino
I
I
Nonaka
I
I
D017668:Age of Onset; D001921:Brain / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D017241:MELAS Syndrome / Q000503:physiopathology*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D017237:Mitochondrial Encephalomyopathies