Bioactive amides from Glycosmis species.
Besides the known imide ritigalin (9), six new phenethyl/styrylamine-derived amides isolated from lipophilic leaf extracts of Glycosmis cf. mauritiana, Glycosmis cf. cyanocarpa, and Glycosmis crassifolia displayed pronounced antifungal and/or insecticidal activity against Cladosporium herbarum and Spodoptera littoralis, respectively, the methylthiocarbonic acid derivatives niranin (1), dehydroniranin A (2), and dehydroniranin B (3) as well as the isovaleric and senecioic acid derivatives thalebanin B (4), dehydrothalebanin B (5), and dehydrothalebanin A (6).
Greger
H
H
Comparative Phytochemistry Department, Institute of Botany, University of Vienna, Wien, Austria.
Zechner
G
G
Hofer
O
O
Vajrodaya
S
S
D000577:Amides / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity; D000818:Animals; D000935:Antifungal Agents / Q000302:isolation & purification* / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D005658:Fungi / Q000187:drug effects*; D007306:Insecticides / Q000302:isolation & purification* / Q000633:toxicity; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D010944:Plants / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D018411:Spodoptera; D013343:Styrenes / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity
D000577:Amides; D000935:Antifungal Agents; D007306:Insecticides; D010936:Plant Extracts; D013343:Styrenes