[The blood-stimulating properties of lysine baicalinate].
The possibility of stimulating hemopoiesis inhibited by a single dose (2.0 Gr) of total irradiation with Lysini Baicalinatum, a vegetable origin drug, has been studied on CBA mice. A 3-fold drug administration (total dose 150 mg/kg) on days 3, 4, and 5 after irradiation promoted bone marrow erythropoiesis and less granulopoiesis. A mechanism of Lysini Baicalinatum stimulating effect is connected with intensification of hemopoiesis inducing microenvironment's functional activity.
Agafonov
V I
VI
Dygaĭ
A M
AM
Litvinenko
V I
VI
Popova
T P
TP
Gol'dberg
E D
ED
D000818:Animals; D001853:Bone Marrow / Q000187:drug effects / Q000528:radiation effects; D003114:Colony-Forming Units Assay; D006410:Hematopoiesis / Q000187:drug effects* / Q000528:radiation effects; D008239:Lysine / Q000031:analogs & derivatives* / Q000494:pharmacology; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D010936:Plant Extracts / Q000494:pharmacology*; D013268:Stimulation, Chemical; D013997:Time Factors; D014916:Whole-Body Irradiation
D010936:Plant Extracts; C103880:lysine baicalinate; D008239:Lysine