title: [Smoking and pregnancy: search for a correlation between cotininemia and Doppler findings].
abstract: OBJECTIVE
  To search for a possible correlation between an effective marker of smoking and uterine and placental resistance during pregnancy.
  
  
  METHODS
  A prospective study was conducted at the Intercommunal Hospital Center of Montreuil, France: 81 healthy pregnant women underwent uterine and placental Doppler and cotidin blood assay, the best current test for smoking.
  
  
  RESULTS
  This study shows a significative increase of utero-placental vascular resistances according with increased cotidine levels.
  
  
  CONCLUSIONS
  The previously observed association between smoking and perinatal events most likely involves vascular resistance of uterus and placenta.
authors.affiliation: Service de Gynécologie-Obstétrique, Centre Hospitalier Intercommunal, Montreuil.
authors.forename: A
authors.initials: A
authors.lastname: Lymperopoulou
authors.forename: F
authors.initials: F
authors.lastname: Hainaut
authors.forename: P
authors.initials: P
authors.lastname: Crimail
authors.forename: J L
authors.initials: JL
authors.lastname: Durand
authors.forename: C
authors.initials: C
authors.lastname: Locatelli
authors.forename: C
authors.initials: C
authors.lastname: Maison
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D003367:Cotinine / Q000097:blood*; D005260:Female; D006801:Humans; D021041:Placental Circulation; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood* / Q000000981:diagnostic imaging*; D011446:Prospective Studies; D012907:Smoking / Q000097:blood*; D016216:Ultrasonography, Prenatal; D014655:Vascular Resistance
chemical_list: D015415:Biomarkers; D003367:Cotinine