title: [Central (reparative) giant cell granuloma of the paranasal sinus].
abstract: BACKGROUND
  The central giant-cell (reprative) granuloma is an uncommon bone lesion usually located in the mandible and maxilla. In contrast to giant cell tumors of the extra-craniofacial skeleton, the origin of this lesion is considered to be non-neoplastic, reactive, and triggered by trauma or inflammation. The tumor occurs mainly in young people; they complain of regional indolent swelling of the jaw eventually leading to loosening of the teeth.
  
  
  METHODS
  In the paper, the authors describe the unusual case of a central giant-cell granuloma in a young male. Diagnostic procedures, adequate therapeutic approach, and an overview of differential diagnostic considerations are provided.
  
  
  RESULTS
  The pedunculate tumor was removed surgically. In endoscopic controls no recurrent growth has been seen up to one year after removal.
  
  
  CONCLUSIONS
  Even though the giant-cell reparative granuloma is rare, it may also occur in the nasal cavity. Diagnosis is established by histologic findings and the typical clinical appearance. Surgical removal is the treatment of choice.
authors.affiliation: Klinik und Poliklinik für Hals-, Nasen- und Ohrenkranke der Ludwig-Maximilians Universität, München.
authors.forename: P
authors.initials: P
authors.lastname: Ostertag
authors.forename: A
authors.initials: A
authors.lastname: Leunig
authors.forename: G
authors.initials: G
authors.lastname: Grevers
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D004724:Endoscopy; D006101:Granuloma, Giant Cell / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed