title: Use of a collagen plug versus manual compression for sealing arterial puncture site after cardiac catheterization.
abstract: The aim of the study was to investigate (1) the safety and efficacy of the application of a collagen plug (Vasoseal) at arterial puncture sites, (2) the hemostasis time, and (3) the comfort for the patient of a collagen plug (Vasoseal) when compared with manual compression. Sixty-two patients were randomized either for application of a collagen plug (Vasoseal, group A, n = 33) or manual compression (group B, n = 29) after cardiac catheterization. All patients were evaluated for subjective pain score ranging from 1 to 5 (1 = no pain up to 5 = very strong pain). In addition the authors measured the time until hemostasis could be achieved. The patients were evaluated by duplex sonography for complications at days 1 and 7 after the procedure. The pain score demonstrated a significantly lower score in group A when compared with group B (P = 0.01). The mean time for hemostasis was significantly lower in group A (mean 9.6 minutes) when compared with group B (mean 23.6 minutes) (P = 0.0001). Regarding the complication rate there was no significant difference between the groups (group A vs group B, P = 0.82). The authors conclude that the application of a collagen plug at the arterial puncture site is a safe and time-saving method. In addition it is less painful and therefore better tolerated than manual compression.
authors.affiliation: Department of Cardiology, University of Vienna.
authors.forename: M
authors.initials: M
authors.lastname: Gwechenberger
authors.forename: R
authors.initials: R
authors.lastname: Katzenschlager
authors.forename: G
authors.initials: G
authors.lastname: Heinz
authors.forename: M
authors.initials: M
authors.lastname: Gottsauner-Wolf
authors.forename: P
authors.initials: P
authors.lastname: Probst
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D001672:Biocompatible Materials; D006328:Cardiac Catheterization; D003094:Collagen / Q000627:therapeutic use*; D005260:Female; D006487:Hemostasis; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011312:Pressure; D011446:Prospective Studies; D011677:Punctures; D013997:Time Factors; D018615:Ultrasonography, Doppler, Color; D018616:Ultrasonography, Doppler, Duplex
chemical_list: D001672:Biocompatible Materials; D006490:Hemostatics; D003094:Collagen