title: An update of the DEF database of protein fold class predictions.
abstract: An update is given on the Database of Expected Fold classes (DEF) that contains a collection of fold-class predictions made from protein sequences and a mail server that provides new predictions for new sequences. To any given sequence one of 49 fold-classes is chosen to classify the structure related to the sequence with high accuracy. The updated prediction system is developed using data from the new version of the 3D-ALI database of aligned protein structures and thus is giving more reliable and more detailed predictions than the previous DEF system.
authors.affiliation: Synaptic Ltd, Aristotelous 313, 13671 Acharnai, Greece.
authors.forename: M
authors.initials: M
authors.lastname: Reczko
authors.forename: D
authors.initials: D
authors.lastname: Karras
authors.forename: H
authors.initials: H
authors.lastname: Bohr
mesh_terms: D000595:Amino Acid Sequence; D016208:Databases, Factual; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry*; D016415:Sequence Alignment
chemical_list: D011506:Proteins