[Treatment of drug-induced agranulocytosis with granulocyte colony stimulating factor (G-CSF) in a surgical intensive care unit].
Following repeated metamizole applications a 41-year old intensive-care patient suffering from severe craniocerebral trauma and sepsis developed a drug-induced agranulocytosis. Early G-CSF treatment reduced the neutropenic period to 4 days.
Huss
B
B
Institut für Anästhesiologie und Operative Intensivmedizin, Klinikum Darmstadt, Johann-Wolfgang-Goethe-Universität Frankfurt/Main.
Bogosyan
S
S
Müller
E
E
Götz
E
E
D000328:Adult; D000380:Agranulocytosis / Q000139:chemically induced* / Q000628:therapy; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use; D003422:Critical Care; D004177:Dipyrone / Q000009:adverse effects* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage*; D016489:Head Injuries, Closed / Q000628:therapy*; D006801:Humans; D008297:Male
D000894:Anti-Inflammatory Agents, Non-Steroidal; D016179:Granulocyte Colony-Stimulating Factor; D004177:Dipyrone