title: Pityriasis rotunda: a survey of 42 cases observed in Sardinia, Italy.
abstract: BACKGROUND
  Pityriasis rotunda (PR) is an uncommon dermatosis characterized by multiple, round or oval, sharply demarcated scaling patches that are dyschromic and asymptomatic. It has been described in Japanese and in blacks, usually in association with certain infective or malignant systemic diseases.
  
  
  OBJECTIVE
  The aim of this study is to further clarify this rare entity which in Italy seems to be confined to the island of Sardinia.
  
  
  METHODS
  We studied 42 Sardinian patients, 22 males and 20 females, in an age range of 3-32 years. In 29 cases, the disease involved more than one family member. The patients were observed in Cagliari, the capital city of Sardinia.
  
  
  RESULTS
  Bacterial, viral and fungal investigation yielded negative results. Haematochemical and immunological examination and thyroid, hypophyseal and adrenal hormones did not reveal any alterations. No systemic pathologies were found associated with the disease.
  
  
  CONCLUSIONS
  The cases studied by us and those previously reported seem to indicate the presence of two distinct types of PR with significant prognostic differences.
authors.affiliation: Clinic of Dermatology, University of Cagliari, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Aste
authors.forename: M
authors.initials: M
authors.lastname: Pau
authors.forename: N
authors.initials: N
authors.lastname: Aste
authors.forename: P
authors.initials: P
authors.lastname: Biggio
mesh_terms: D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000032:analysis; D000328:Adult; D001419:Bacteria / Q000302:isolation & purification; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D005658:Fungi / Q000302:isolation & purification; D006801:Humans; D007558:Italy; D007642:Keratosis / Q000473:pathology; D008297:Male; D010907:Pituitary Hormones / Q000032:analysis; D010915:Pityriasis / Q000097:blood / Q000235:genetics / Q000276:immunology / Q000382:microbiology / Q000473:pathology* / Q000821:virology; D011379:Prognosis; D012075:Remission, Spontaneous; D013963:Thyroid Hormones / Q000032:analysis; D014780:Viruses / Q000302:isolation & purification
chemical_list: D000305:Adrenal Cortex Hormones; D010907:Pituitary Hormones; D013963:Thyroid Hormones