title: Malignant histiocytosis in a Bernese mountain dog presenting as a mandibular mass.
abstract: A Bernese mountain dog was evaluated because of a gingival mass, multiple abdominal masses, and a pulmonary mass. Malignant histiocytosis was diagnosed based on cytological examination of splenic and bone marrow aspirates and histological examination of a bone marrow biopsy and the gingival mass. The case demonstrates that malignant histiocytosis is difficult to diagnose due to the variety of histiocytic disorders.
authors.affiliation: Department of Clinical Studies, Ontario Veterinary College, University of Guelph.
authors.forename: L
authors.initials: L
authors.lastname: Carioto
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000378:metabolism / Q000473:pathology*; D004285:Dogs; D005881:Gingiva / Q000473:pathology; D054747:Histiocytic Sarcoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D008297:Male; D008339:Mandibular Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D009113:Muramidase / Q000378:metabolism; D013154:Spleen / Q000473:pathology; D000515:alpha 1-Antitrypsin / Q000378:metabolism
chemical_list: D000515:alpha 1-Antitrypsin; D009113:Muramidase