title: [The adhesive activity of Klebsiella pneumoniae controlled by plasmid 55 MD].
abstract: In K. pneumoniae clinical strains a nonconjugative plasmid, denoted as pAdh-55 and responsible for their adhesive activity with respect to HEp-2 cells, was detected. The comparison of genetically related pairs of K. pneumoniae strains differing in the presence of pAdh-55 revealed that the loss of this plasmid by bacteria was accompanied by a decrease, and its acquisition by a considerable increase, in the number of Klebsiella-affected cells in the monolayer. The correlation between the presence of pAdh-55 in K. pneumoniae strains and their adhesive activity was established both in experiments aimed at the morphological study of preparations stained with azure eosin and in experiments with isotope-labeled bacteria.
authors.forename: V M
authors.initials: VM
authors.lastname: Bondarenko
authors.forename: G Ia
authors.initials: GIa
authors.lastname: Tseneva
authors.forename: L A
authors.initials: LA
authors.lastname: Berezina
authors.forename: G
authors.initials: G
authors.lastname: Wu
authors.forename: E V
authors.initials: EV
authors.lastname: Sudzhian
mesh_terms: D001422:Bacterial Adhesion; D014644:Genetic Variation / Q000235:genetics; D006801:Humans; D007711:Klebsiella pneumoniae / Q000235:genetics / Q000472:pathogenicity*; D008970:Molecular Weight; D010957:Plasmids / Q000235:genetics; D013997:Time Factors; D014407:Tumor Cells, Cultured