title: [Equine arteritis virus: clinical symptoms and prevention].
abstract: Sero-epidemiological surveys have revealed that equine arteritis virus (EAV) is prevalent in most European countries. The virus causes sporadic cases of respiratory disease and abortion in horses, the incidence of which has increased in recent years. Mares and geldings eliminate virus after acute infection, but 30% to 60% of stallions become persistently infected. In these animals, EAV is maintained within the reproductive tract and is shed continuously in the semen. Persistent infection with EAV in stallions has no negative consequences for fertility but mares inseminated with virus-contaminated semen can have an acute infection. These mares shed large amounts of virus in respiratory secretions and urine, leading to lateral spread of the virus to other susceptible horses. Acute infection at later stages of gestation can lead to abortion. Effective control of the spread of EAV infection depends on the identification of virus-shedding stallions. Persistently infected stallions should not be used for breeding or should be bred only to seropositive mares. Mares bred to shedding stallions should be isolated from other animals for a period of 3 weeks following insemination to prevent the lateral spread of EAV.
authors.affiliation: Universiteit Utrecht, Faculteit der Diergeneeskunde, Vakgroep Infectieziekten en Immunologie.
authors.forename: A L
authors.initials: AL
authors.lastname: Glaser
authors.forename: A A
authors.initials: AA
authors.lastname: de Vries
authors.forename: P J
authors.initials: PJ
authors.lastname: Rottier
authors.forename: M C
authors.initials: MC
authors.lastname: Horzinek
authors.forename: B
authors.initials: B
authors.lastname: Colenbrander
mesh_terms: D000034:Abortion, Veterinary / Q000821:virology; D000818:Animals; D018174:Arterivirus Infections / Q000453:epidemiology / Q000517:prevention & control / Q000635:transmission / Q000662:veterinary*; D002353:Carrier State / Q000662:veterinary; D007240:Equartevirus / Q000276:immunology; D005260:Female; D006734:Horse Diseases / Q000821:virology*; D006736:Horses; D008297:Male; D011247:Pregnancy; D016036:Seroepidemiologic Studies; D014765:Viral Vaccines
chemical_list: D014765:Viral Vaccines