title: [The neuroendocrine mechanisms of the development of the anovulatory hyperandrogenic syndrome in rats].
abstract: The anovulatory syndrome in adult female rats occurred after subcutaneous implantation of silastic capsules with testosterone. Acceleration of testosterone conversion into estradiol in the hypothalamus, suppression of pituitary LH responsiveness to LHRH, increase of blood plasma bioactive LH, estrous cycle disorder as well as morphological changes in ovaries demonstrate the alterations in neuroendocrine control of ovulation.
authors.forename: O H
authors.initials: OH
authors.lastname: Reznikov
authors.forename: P V
authors.initials: PV
authors.lastname: Sinitsyn
authors.forename: L V
authors.initials: LV
authors.lastname: Tarasenko
authors.forename: L I
authors.initials: LI
authors.lastname: Poliakov
mesh_terms: D000818:Animals; D000858:Anovulation / Q000139:chemically induced / Q000378:metabolism / Q000503:physiopathology*; D004195:Disease Models, Animal; D004343:Drug Implants; D004971:Estrus / Q000187:drug effects; D005260:Female; D007987:Gonadotropin-Releasing Hormone / Q000008:administration & dosage / Q000378:metabolism; D017588:Hyperandrogenism / Q000139:chemically induced / Q000378:metabolism / Q000503:physiopathology*; D007031:Hypothalamus / Q000378:metabolism; D007986:Luteinizing Hormone / Q000097:blood; D009490:Neurosecretory Systems / Q000187:drug effects / Q000503:physiopathology*; D051381:Rats; D013577:Syndrome; D013739:Testosterone / Q000008:administration & dosage / Q000378:metabolism; D013997:Time Factors
chemical_list: D004343:Drug Implants; D007987:Gonadotropin-Releasing Hormone; D013739:Testosterone; D007986:Luteinizing Hormone