[Immune system function in the participants in the cleanup of the aftermath of the accident at the Chernobyl Atomic Electric Power Station].
Imbalance was revealed in the proportions of T-lymphocyte subpopulations in those persons engaged in activity in mining employment who had been exposed to a complex of the radiation accident factors. Maximum reduction in the lymphocyte suppressor activity was recordable in those patients in whom the doses of radioactive irradiation received exceeded 25 s Gy. Depression was found of humoral immunity manifested by a drop in the absolute as well as relative numbers of B-lymphocytes and fall in the blood serum levels of Ig G, A. The results of study of clinical-biochemical and immunologic parameters of blood permit individualized therapies be developed, prophylactic measures to be devised to deal with the relevant pathologic processes and conditions in the cohorts examined.
Ivanitskaia
N F
NF
Savchenko
M V
MV
Sorokina
S F
SF
Li
Ia B
IaB
D000328:Adult; D000917:Antibody Formation / Q000528:radiation effects; D006801:Humans; D007107:Immune System / Q000276:immunology / Q000502:physiology / Q000528:radiation effects*; D007111:Immunity, Cellular / Q000528:radiation effects; D008297:Male; D008875:Middle Aged; D008906:Mining; D016273:Occupational Exposure / Q000009:adverse effects*; D011210:Power Plants; D011829:Radiation Dosage; D018788:Radioactive Hazard Release; D014455:Ukraine