title: Evaluation of Bionike one-step tests for the detection of drugs of abuse in urine.
abstract: Bionike one-step tests were used to screen urine samples for amphetamines, methamphetamines, benzodiazepines, cannabinoids, methadone and opiates, and results were compared with those obtained using enzyme multiplied immunoassay technique d.a.u. assays. Taking into consideration different threshold levels and possible differences in cross-reactivities, there was good agreement between the methods. Results of Bionike tests correlated well with amphetamines, methadone and opiates detected in urine using gas chromatography-mass spectrometry. Bionike methods are rapid, simple to use, and relatively inexpensive for on-site testing of individual drugs or groups of drugs in urine.
authors.affiliation: Department of Clinical Biochemistry, Royal Infirmary, Edinburgh, UK.
authors.forename: E R
authors.initials: ER
authors.lastname: Brown
authors.forename: D R
authors.initials: DR
authors.lastname: Jarvie
authors.forename: D
authors.initials: D
authors.lastname: Simpson
mesh_terms: D000661:Amphetamine / Q000652:urine; D001569:Benzodiazepines / Q000652:urine; D002186:Cannabinoids / Q000652:urine; D002624:Chemistry, Clinical / Q000295:instrumentation / Q000379:methods*; D002849:Chromatography, Gas / Q000379:methods; D003955:Diagnostic Tests, Routine / Q000295:instrumentation / Q000379:methods; D005189:False Positive Reactions; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods; D008691:Methadone / Q000652:urine; D008694:Methamphetamine / Q000652:urine; D009294:Narcotics / Q000652:urine; D012680:Sensitivity and Specificity; D019966:Substance-Related Disorders / Q000652:urine*
chemical_list: D002186:Cannabinoids; D009294:Narcotics; D001569:Benzodiazepines; D008694:Methamphetamine; D000661:Amphetamine; D008691:Methadone