Desmoplastic malignant melanoma of the gingiva: case report and review of the literature.
A rare case of desmoplastic melanoma arising from the maxillary gingiva of a 66-year-old woman is reported. This tumour metastasised to the submandibular lymph node 5 years after extirpation, and local recurrence was observed 2 years later. The gingival tumour showed the histopathological characteristics of desmoplastic melanoma and the metastasised tumour cells were immunohistochemically positive for S-100 protein, neuron specific enolase, HMB-45 highly specific for conventional melanoma, and Fontana-Masson staining. The gingival tumour, originally regarded as benign clinically, was actually a desmoplastic melanoma.
Ueta
E
E
Department of Oral Surgery, Kochi Medical School, Japan.
Miki
T
T
Osaki
T
T
Iwata
J
J
Sonobe
H
H
D000368:Aged; D003951:Diagnostic Errors; D005260:Female; D005887:Gingival Neoplasms / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D008207:Lymphatic Metastasis; D008545:Melanoma / Q000378:metabolism / Q000473:pathology* / Q000556:secondary; D009364:Neoplasm Recurrence, Local