title: [Osteomyelitis sicca in Crohn disease--coincidence or extraintestinal manifestation?].
abstract: In patients with Crohn's disease arthritis of the large joints, osteomalacia, osteoporosis and aseptic bone necrosis as a consequence of malabsorption and glucocorticoid intake may occur. The case of a patient with long-standing Crohn's disease is presented who subsequently developed abacterial osteomyelitis of the jaw ("osteomyelitis sicca"). The symptoms of the osteomyelitis improved under immuno-suppressive therapy. Because the etiopathogenetic concepts for Crohn's disease and osteomyelitis sicca are similar, the latter could be a rare extraintestinal manifestation in Crohn's disease, not described previously.
authors.affiliation: Medizinische Klinik, Ludwig-Maximilians Universität, München.
authors.forename: C
authors.initials: C
authors.lastname: Folwaczny
authors.forename: M
authors.initials: M
authors.lastname: Folwaczny
authors.forename: W A
authors.initials: WA
authors.lastname: Winter
authors.forename: H
authors.initials: H
authors.lastname: Daschner
authors.forename: W
authors.initials: W
authors.lastname: Heldwein
authors.forename: K
authors.initials: K
authors.lastname: Loeschke
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D003424:Crohn Disease / Q000175:diagnosis* / Q000188:drug therapy; D003646:Debridement; D003952:Diagnostic Imaging; D004359:Drug Therapy, Combination; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D008297:Male; D008336:Mandibular Diseases / Q000175:diagnosis* / Q000188:drug therapy; D015122:Mercaptopurine / Q000008:administration & dosage; D008775:Methylprednisolone / Q000008:administration & dosage; D010019:Osteomyelitis / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D007166:Immunosuppressive Agents; D015122:Mercaptopurine; D008775:Methylprednisolone