title: Hydroxyapatite in revision of total hip replacements with massive acetabular defects: 4- to 10-year clinical results.
abstract: Hydroxyapatite (HA) granules of 100 to 300 microm, 0.9 to 1.2 mm and 3.0 to 5.0 mm were mixed in a ratio of 10:45:45 and packed into massive bone deficiencies in revision operations for total hip arthroplasty. We did not use additional graft or cup support for deficiencies of the lateral and medial wall. The procedure was carried out in 40 hips between 1986 and 1992. The radiographic spaces seen at the interface between HA and bone immediately after surgery disappeared within three months. Some spaces appeared between HA granules near the bone in the lateral part of two joints, and three sockets migrated in patients with severe segmental and cavitary deficiencies. Direct bonding of HA to bone was observed radiologically without morphological changes, except in the three joints with migration. All patients could walk without pain but the three with definite loosening needed crutches.
authors.affiliation: Department of Orthopaedic Surgery, Osaka-Minami National Hospital, Kawachinagano-Shi, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Oonishi
authors.forename: Y
authors.initials: Y
authors.lastname: Iwaki
authors.forename: N
authors.initials: N
authors.lastname: Kin
authors.forename: S
authors.initials: S
authors.lastname: Kushitani
authors.forename: N
authors.initials: N
authors.lastname: Murata
authors.forename: S
authors.initials: S
authors.lastname: Wakitani
authors.forename: K
authors.initials: K
authors.lastname: Imoto
mesh_terms: D000077:Acetabulum / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001172:Arthritis, Rheumatoid / Q000601:surgery; D001672:Biocompatible Materials / Q000008:administration & dosage*; D017886:Durapatite / Q000008:administration & dosage*; D005260:Female; D006622:Hip Prosthesis; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000601:surgery; D010020:Osteonecrosis / Q000601:surgery; D011183:Postoperative Complications; D012086:Reoperation
chemical_list: D001672:Biocompatible Materials; D017886:Durapatite