title: Comparison of RapiTest with Emit d.a.u. and GC-MS for the analysis of drugs in urine.
abstract: Results obtained with RapiTest THC (One Step delta 9-Tetrahydrocannabinol Test), RapiTest MOP (One Step Morphine Test), RapiTest MET (One Step Methamphetamine Test), and RapiTest COC (One Step Cocaine Test) were compared with the results obtained with Emit d.a.u. and with gas chromatographic-mass spectrometric (GC-MS) methods. In all, 81 urine samples taken from specimens submitted for routine analysis in the Laboratory of Pharmacology and Toxicology were analyzed. Samples were screened with Emit, reanalyzed by RapiTests, and quantitated using GC-MS methods. Both positive and negative urine samples were tested. The results obtained with RapiTests correlated well with the Emit d.a.u. and GC-MS data when operating above the cutoff concentrations specified for these methods. RapiTest MOP was found to have crossreactivity with codeine and ethylmorphine, and RapiTest MET crossreacted with amphetamine.
authors.affiliation: National Public Health Institute, Laboratory of Pharmacology and Toxicology, Helsinki, Finland.
authors.forename: T
authors.initials: T
authors.lastname: Korte
authors.forename: J
authors.initials: J
authors.lastname: Pykäläinen
authors.forename: P
authors.initials: P
authors.lastname: Lillsunde
authors.forename: T
authors.initials: T
authors.lastname: Seppälä
mesh_terms: D002186:Cannabinoids / Q000652:urine; D003042:Cocaine / Q000652:urine; D003429:Cross Reactions; D013759:Dronabinol / Q000652:urine; D017248:Enzyme Multiplied Immunoassay Technique; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D006801:Humans; D013287:Illicit Drugs / Q000652:urine*; D008694:Methamphetamine / Q000652:urine; D009020:Morphine / Q000652:urine; D009294:Narcotics / Q000652:urine; D015813:Substance Abuse Detection / Q000379:methods*
chemical_list: D002186:Cannabinoids; D013287:Illicit Drugs; D009294:Narcotics; D008694:Methamphetamine; D009020:Morphine; D013759:Dronabinol; D003042:Cocaine