title: [Histamine liberation (or histamine release HR): study of the positivity threshold in hymenoptera venom allergy].
abstract: Dialysis of Hymenoptera venoms for measurement of HR by the radioimmunoassay technique (RIA, Immunotech) lowers the threshold of positivity of the HR titre from 30% to 12%. This modification of dialysis of the venoms significantly improves the sensitivity and specificity of the technique.
authors.affiliation: Laboratoire d'Immuno-Allergologie, CHU, Angers.
authors.forename: M
authors.initials: M
authors.lastname: Minkhar
authors.forename: G
authors.initials: G
authors.lastname: Giffard
authors.forename: M G
authors.initials: MG
authors.lastname: Lauret
authors.forename: S
authors.initials: S
authors.lastname: Hassoun
authors.forename: M
authors.initials: M
authors.lastname: Drouet
authors.forename: J
authors.initials: J
authors.lastname: Sainte-Laudy
authors.forename: A
authors.initials: A
authors.lastname: Sabbah
mesh_terms: D001514:Bee Venoms / Q000276:immunology / Q000302:isolation & purification / Q000494:pharmacology*; D003956:Dialysis; D004306:Dose-Response Relationship, Immunologic; D006636:Histamine Release / Q000187:drug effects*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000209:etiology / Q000276:immunology*; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D007428:Intradermal Tests; D011863:Radioimmunoassay; D012680:Sensitivity and Specificity; D014862:Wasp Venoms / Q000276:immunology / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D001514:Bee Venoms; D014862:Wasp Venoms; D007073:Immunoglobulin E