Natural and vaccine-induced immunity to foot and mouth disease: the prospects for improved vaccines.
The review considers both the immune responses of livestock to foot and mouth disease (FMD) virus after infection or vaccination, and the characteristics and properties of FMD viruses and vaccines which are relevant to protection. Particular attention is given to possible approaches which could be used to improve conventional vaccines or produce novel vaccines against this most important disease.
Doel
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Rhône-Mérieux Ltd., Pirbright, Woking, Surrey, United Kingdom.
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis*; D005537:Aphthovirus / Q000276:immunology*; D002353:Carrier State / Q000276:immunology / Q000662:veterinary; D002417:Cattle; D004355:Drug Stability; D005536:Foot-and-Mouth Disease / Q000276:immunology* / Q000517:prevention & control; D007111:Immunity, Cellular; D018928:Immunity, Mucosal; D012756:Sheep; D013045:Species Specificity; D013552:Swine; D013601:T-Lymphocytes / Q000276:immunology; D013997:Time Factors; D014765:Viral Vaccines / Q000276:immunology* / Q000592:standards*
D000914:Antibodies, Viral; D014765:Viral Vaccines