title: Connective tissue metabolism in scleroderma, including cytokines.
abstract: The recent literature on scleroderma emphasizes the importance of cytokine dysregulation, cell-cell interactions, and extracellular matrix overproduction in the pathogenesis of this disease. Advances in our understanding of these areas are discussed here.
authors.affiliation: Connective Therapeutics Incorporated, Palo Alto, CA 94303, USA.
authors.forename: E N
authors.initials: EN
authors.lastname: Unemori
authors.forename: E P
authors.initials: EP
authors.lastname: Amento
mesh_terms: D000818:Animals; D002450:Cell Communication / Q000502:physiology*; D002455:Cell Division; D003238:Connective Tissue / Q000502:physiology; D016207:Cytokines / Q000502:physiology*; D004727:Endothelium / Q000502:physiology; D005109:Extracellular Matrix / Q000502:physiology*; D005347:Fibroblasts / Q000502:physiology; D006801:Humans; D012595:Scleroderma, Systemic / Q000209:etiology* / Q000503:physiopathology*
chemical_list: D016207:Cytokines