title: [Rationale for the use of regional lymphotropic therapy in the management of tuberculosis in adolescents].
abstract: Regional lymphotropic therapy involves the administration of a antituberculous drug (isoniazid or canamycin) into the pretracheal cellular space or subaxillary region on the damage ipsilateral side with daily alternations of injection sites. A hundred and thirty two patients with active tuberculosis types (mainly infiltrative) who form two equal groups: main (lymphotropic therapy) and control (routine treatments) were followed up. Lymphotropic therapy is well tolerated by patients, particularly in the presence of concurrent gastrointestinal diseases, produces no adverse reactions, promotes more rapid resolution of infiltrative changes and elimination of intoxication signs. A more rapid positive dynamics in the main group than that in the control one allows the duration of hospital stay to be reduced by 2-2.5 months.
authors.affiliation: Central NII of Tuberculosis RAMN, Moscow.
authors.forename: V A
authors.initials: VA
authors.lastname: Firsova
authors.forename: M F
authors.initials: MF
authors.lastname: Gubkina
mesh_terms: D000293:Adolescent; D000995:Antitubercular Agents / Q000627:therapeutic use*; D001365:Axilla; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D007538:Isoniazid / Q000627:therapeutic use*; D007612:Kanamycin / Q000627:therapeutic use*; D007902:Length of Stay; D008198:Lymph Nodes; D014132:Trachea; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents; D007612:Kanamycin; D007538:Isoniazid