title: Cognitive function in elderly non-insulin-dependent diabetic patients before and after inpatient treatment for metabolic control.
abstract: Cognitive function was measured before and after inpatient treatment for metabolic control in 20 elderly patients with non-insulin-dependent diabetes mellitus (NIDDM). Another 20 patients still on the waiting list for this treatment, served as a control group. Glycosylated hemoglobin decreased in both groups. Psychomotor speed and concentration improved only after inpatient treatment (p < 0.01; p < 0.05, respectively). Improved performance was maintained and even enhanced 6 weeks after discharge from inpatient treatment. Performance in concentration tasks correlated with glycosylated hemoglobin (p < 0.05). It is concluded that cognitive deficits in elderly NIDDM patients can be reduced by inpatient treatment, although the benefit of glycemic control was not clearly demonstrated in this study.
authors.affiliation: Institute for Psychology, Aachen Technical University, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Naor
authors.forename: H J
authors.initials: HJ
authors.lastname: Steingrüber
authors.forename: K
authors.initials: K
authors.lastname: Westhoff
authors.forename: Y
authors.initials: Y
authors.lastname: Schottenfeld-Naor
authors.forename: A F
authors.initials: AF
authors.lastname: Gries
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D001288:Attention / Q000502:physiology; D001307:Auditory Perception / Q000502:physiology; D001786:Blood Glucose / Q000032:analysis / Q000378:metabolism; D003071:Cognition / Q000502:physiology*; D015331:Cohort Studies; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology* / Q000628:therapy*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis / Q000378:metabolism; D006801:Humans; D007297:Inpatients; D008297:Male; D008875:Middle Aged; D011597:Psychomotor Performance / Q000502:physiology; D011930:Reaction Time / Q000502:physiology; D013997:Time Factors; D014796:Visual Perception / Q000502:physiology
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin