[Changes in membrane potential and cell volume of Balb C mice T  lymphocytes in different physiological conditions in media with different content of D2O].
It is shown that the changes in membrane potential of thymocytes in aqueous medium with a definite D2O concentration are due to changes in the Na/K-ATPase activity. Low D2O concentrations activate whereas high concentrations inhibit the enzymatic reaction. The experimental data obtained suggest the discreteness of functionally active conformations of the enzyme.
Zatsepina
G N
GN
Vengrus
T V
TV
Goriunov
N N
NN
D000818:Animals; D002478:Cells, Cultured; D003470:Culture Media; D017666:Deuterium Oxide; D007249:Inflammation; D008564:Membrane Potentials; D051379:Mice; D008807:Mice, Inbred BALB C; D013601:T-Lymphocytes / Q000502:physiology*
D003470:Culture Media; D017666:Deuterium Oxide