Plasma leptin levels and body fat distribution.
The relation between body fat distribution and plasma leptin levels in the human was investigated in 51 obese and 41 non-obese subjects. Plasma levels of leptin showed a positive correlation with body mass index and subcutaneous fat area at the umbilicus level. However, a significant correlation between its plasma levels and visceral fat area was found in neither non-obese nor obese subjects. These results suggest that plasma leptin levels might be attributed mainly to the extent of subcutaneous adiposity in human obesity.
Takahashi
M
M
Second Department of Internal Medicine, Osaka University, Medical School, Japan.
Funahashi
T
T
Shimomura
I
I
Miyaoka
K
K
Matsuzawa
Y
Y
D000273:Adipose Tissue; D000328:Adult; D001823:Body Composition; D015992:Body Mass Index; D005260:Female; D006801:Humans; D020738:Leptin; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood* / Q000503:physiopathology; D011506:Proteins / Q000378:metabolism*; D014472:Umbilicus
D020738:Leptin; D011506:Proteins