Predictors of mortality after acute hip fracture.
To identify determinants of mortality after hip fracture, we performed a multicenter, retrospective study of 390 Medicare beneficiaries. Independent predictors of 30-day mortality included a history of congestive heart failure (odds ratio [OR] 32; 95% confidence interval [CI] 5, 192), angina (OR 26; 95% CI 4, 184), or chronic pulmonary disease (OR 11; 95% CI 2, 62). Postoperative use of aspirin was associated with a reduced risk of mortality (OR 0.24; 95% CI 0.08, 0.70). Cardiovascular events were the presumed cause of 63% of in-hospital deaths. Aspirin may have significant potential to reduce mortality in this population and deserves further study.
Nettleman
M D
MD
Department of Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, USA.
Alsip
J
J
Schrader
M
M
Schulte
M
M
D000368:Aged; D000369:Aged, 80 and over; D001241:Aspirin / Q000627:therapeutic use; D015897:Comorbidity; D005260:Female; D006620:Hip Fractures / Q000401:mortality*; D017052:Hospital Mortality; D006801:Humans; D007484:Iowa; D008297:Male; D006278:Medicare / Q000706:statistics & numerical data; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011182:Postoperative Care; D012044:Regression Analysis; D012189:Retrospective Studies; D012307:Risk Factors; D013924:Thrombophlebitis / Q000517:prevention & control; D014481:United States
D010975:Platelet Aggregation Inhibitors; D001241:Aspirin