Effect of serum from breast- or formula-fed infants on polymorphonuclear leukocyte function.
The aim of the present study was to determine the influence of serum from formula and breast-fed infants on neutrophil function (as measured by the attachment and phagocytosis of Candida albicans) as well as the chemoattractant activity of the serum. The results indicate that: (a) serum from breast-fed infants induces a greater chemoattractant activity in neutrophils than serum from 3-month-old formula-fed infants; (b) the highest values of the attachment capacity were obtained after incubation of neutrophils with serum from 1-month-old breast-fed infants; and (c) serum from breast-fed infants induces a greater phagocytic capacity against C. albicans in neutrophils than serum from formula-fed infants.
Barriga Ibars
C
C
Department of Animal Physiology, Faculty of Science, University of Extremadura, Badajoz, Spain.
Rodríguez
A B
AB
Pombero
I
I
Durán
J
J
Cardesa
J
J
Ortega
E
E
D000328:Adult; D000367:Age Factors; D001769:Blood / Q000276:immunology*; D001942:Breast Feeding; D002176:Candida albicans / Q000276:immunology; D002448:Cell Adhesion / Q000276:immunology / Q000502:physiology; D002465:Cell Movement / Q000276:immunology / Q000502:physiology; D002633:Chemotaxis / Q000276:immunology / Q000502:physiology; D006801:Humans; D007223:Infant; D007225:Infant Food; D007231:Infant, Newborn; D009504:Neutrophils / Q000502:physiology*; D010587:Phagocytosis / Q000276:immunology / Q000502:physiology