Motors and membrane traffic.
The cytoskeleton is essential for the proper function of many components of secretory and endocytic pathways, and the importance both of microtubule motors (kinesins and dyneins) and of actin motors (myosins) in these pathways is becoming apparent. Recent experiments have improved our understanding of which members of these motor protein families are involved in membrane traffic. Multiple motors are probably involved in the control of the morphology and dynamics of many membranes, and intriguing hints about how these motors are coordinated are appearing.
Goodson
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Department of Cell Biology, Sciences III, University of Geneva, 30 quai Ernest Ansermet, 1211 Geneva 4, Switzerland.
Valetti
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C
Kreis
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TE
D000818:Animals; D001692:Biological Transport / Q000502:physiology; D002462:Cell Membrane / Q000378:metabolism*; D004398:Dyneins / Q000737:chemistry / Q000378:metabolism*; D016547:Kinesins / Q000737:chemistry / Q000378:metabolism*; D009218:Myosins / Q000737:chemistry / Q000378:metabolism*
D009218:Myosins; D004398:Dyneins; D016547:Kinesins