Inhibition of viral polymerases by chain-terminating substrates: a kinetic analysis.
Wilson
J E
JE
Division of Biochemistry, Burroughs Wellcome Co., Research Triangle Park, North Carolina 27709, USA.
Porter
D J
DJ
Reardon
J E
JE
D000818:Animals; D001483:Base Sequence; D002417:Cattle; D004247:DNA / Q000494:pharmacology; D017931:DNA Primers; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D054303:HIV Reverse Transcriptase / Q000037:antagonists & inhibitors; D007700:Kinetics; D008297:Male; D008969:Molecular Sequence Data; D019384:Nucleic Acid Synthesis Inhibitors; D009838:Oligodeoxyribonucleotides / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D009843:Oligoribonucleotides / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D011119:Polynucleotides / Q000494:pharmacology; D012474:Salmon; D013094:Spermatozoa / Q000378:metabolism; D013698:Templates, Genetic; D013950:Thymus Gland / Q000378:metabolism; D014780:Viruses / Q000201:enzymology*
D017931:DNA Primers; D004791:Enzyme Inhibitors; D019384:Nucleic Acid Synthesis Inhibitors; D009838:Oligodeoxyribonucleotides; D009843:Oligoribonucleotides; D011119:Polynucleotides; D004247:DNA; D054303:HIV Reverse Transcriptase