title: Ambulatory manometric examination in patients with a colonic J pouch and in normal controls.
abstract: Anorectal function after anterior resection may be impaired as a result of reduced luminal capacity in the pelvis. The aim of this study was to evaluate the colonic J pouch neorectum by means of ambulatory manometry. Twelve patients with a colonic pouch following anterior resection and seven healthy controls were studied for a median of 6 (range 6-24) h using a probe with two pouch-rectal and two anal canal transducers. Records were interpreted by visual inspection. Pressure values and wave frequencies were determined by software analysis. Pouches had been functioning for a median of 32 (range 11-55) months. All patients with a pouch had an acceptable stool frequency. Seven of 12 patients complained of incomplete evacuation. Resting anal canal pressure (73 versus 100 cmH2O), pouch-rectal pressure (29 versus 15 cmH2O) and anal canal pouch-rectal pressure gradients (60 versus 85 cmH2O) were similar in patients and controls. The frequency of slow-wave activity in patients with a pouch was significantly lower than that in controls (7 versus 16 cycles per min, P = 0.001). Coordination between the colonic J pouch and the anal canal, in the form of sampling episodes, was observed in more than half of the patients with a functioning pouch. Large isolated contractions (pressure greater than 30 cmH2O and lasting longer than 20 s) and rhythmic contractions were the most frequent pattern of pouch motility.
authors.affiliation: Department of Colorectal Surgery, John Radcliffe Hospital, Oxford, UK.
authors.forename: J
authors.initials: J
authors.lastname: Romanos
authors.forename: J F
authors.initials: JF
authors.lastname: Stebbing
authors.forename: M M
authors.initials: MM
authors.lastname: Smiligin Humphreys
authors.forename: N
authors.initials: N
authors.lastname: Takeuchi
authors.forename: N J
authors.initials: NJ
authors.lastname: Mortensen
mesh_terms: D000328:Adult; D000368:Aged; D000553:Ambulatory Care; D003672:Defecation / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D011312:Pressure; D016737:Proctocolectomy, Restorative; D012004:Rectal Neoplasms / Q000503:physiopathology* / Q000601:surgery