title: [The biological compatibility of the new noble alloy Superpal for metal-ceramic dentures].
abstract: Toxic characteristics of Superpal, a dental palladium-based alloy for cermet dentures, were studied in a chronic experiment on 20 rats to which it was subcutaneously implanted. Analysis of histological findings, blood biochemistry, mast cell degranulation test, summarization of subthreshold pulses, and the micronucleus test showed that Superpal alloy is biologically inert, nontoxic, exerts no sensitizing and mutagenic effects, and may be used for making cement dentures.
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Lebedenko
authors.forename: E P
authors.initials: EP
authors.lastname: Pustovaia
authors.forename: N M
authors.initials: NM
authors.lastname: Kaminskaia
authors.forename: V N
authors.initials: VN
authors.lastname: Kopeĭkin
authors.forename: V A
authors.initials: VA
authors.lastname: Limarev
authors.forename: S V
authors.initials: SV
authors.lastname: Anisimova
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D001672:Biocompatible Materials / Q000633:toxicity*; D015550:Cell Degranulation / Q000187:drug effects; D003778:Dentures; D006047:Gold Alloys / Q000633:toxicity*; D008297:Male; D008407:Mast Cells / Q000187:drug effects / Q000502:physiology; D008422:Materials Testing / Q000379:methods / Q000706:statistics & numerical data; D016876:Metal Ceramic Alloys / Q000633:toxicity*; D015162:Micronucleus Tests; D010165:Palladium / Q000633:toxicity*; D019736:Prostheses and Implants / Q000009:adverse effects; D051381:Rats; D013997:Time Factors
chemical_list: D001672:Biocompatible Materials; D006047:Gold Alloys; D016876:Metal Ceramic Alloys; D010165:Palladium