Exfoliative dermatitis associated with diltiazem.
BACKGROUND
Exfoliative dermatitis due to calcium channel blockers is a known but infrequent response.


METHODS
A 77-year-old woman began treatment with diltiazem for angina pectoris. Three days later, severe exfoliative dermatitis developed.


CONCLUSIONS
The present case and the others previously reported emphasize the need for greater awareness of the occurrence of adverse cutaneous reactions including toxic epidermal necrolysis, Stevens-Johnson syndrome and cutaneous vasculitis due to calcium channel blockers including diltiazem.
Odeh
M
M
Department of Internal Medicine B, Bnai Zion Medical Center, Technion Faculty of Medicine, Israel Institute of Technology, Haifa, Israel.
D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy*; D002121:Calcium Channel Blockers / Q000009:adverse effects*; D003873:Dermatitis, Exfoliative / Q000139:chemically induced*; D004110:Diltiazem / Q000009:adverse effects*; D003875:Drug Eruptions; D005260:Female; D006801:Humans
D002121:Calcium Channel Blockers; D004110:Diltiazem