title: [The mechanism of the diuretic action of the preparation polyosm].
abstract: The mechanism of the diuretic effect of the new drug polyosm, polyethylene oxide 400 solution, was studied in experiments on anesthetized cats. Intravenous polyosm infusion was attended with a marked diuretic and natriuretic effect developing due to reduced reabsorption of water and natrium and increased glomerular filtration.
authors.forename: M B
authors.initials: MB
authors.lastname: Plotnikov
authors.forename: V I
authors.initials: VI
authors.lastname: Smol'iakova
authors.forename: G A
authors.initials: GA
authors.lastname: Chernysheva
authors.forename: E V
authors.initials: EV
authors.lastname: Ivanova
authors.forename: Ia F
authors.initials: IaF
authors.lastname: Zverev
mesh_terms: D000818:Animals; D002415:Cats; D004231:Diuresis / Q000187:drug effects*; D004234:Diuretics, Osmotic / Q000494:pharmacology*; D005260:Female; D005919:Glomerular Filtration Rate / Q000187:drug effects; D008297:Male; D011092:Polyethylene Glycols / Q000494:pharmacology*; D012996:Solutions; D013997:Time Factors
chemical_list: D004234:Diuretics, Osmotic; D012996:Solutions; D011092:Polyethylene Glycols