title: [The prevention of hemorrhagic cystitis during the performance of bone marrow and peripheral blood stem cell transplantation in the hematologic cancer clinic].
abstract: Investigators from Belarus Center for bone marrow transplantation examined the efficacy of preventing hemorrhagic cystitis induced by high-dose cyclophosphamide in preparation for hemopoiesis precursor transplantation in 22 patients with hematological diseases. The proposed preventive method implied administration of mesna (2-merkaptoetan-sulphonate) and alkaline forced diuresis. Its effectiveness was found high.
authors.forename: A L
authors.initials: AL
authors.lastname: Uss
authors.forename: N F
authors.initials: NF
authors.lastname: Milanovich
authors.forename: V M
authors.initials: VM
authors.lastname: Snegir'
authors.forename: V A
authors.initials: VA
authors.lastname: Zmachinskiĭ
authors.forename: A E
authors.initials: AE
authors.lastname: Skriagin
mesh_terms: D000293:Adolescent; D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002648:Child; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000009:adverse effects; D003556:Cystitis / Q000209:etiology / Q000517:prevention & control*; D004231:Diuresis / Q000187:drug effects; D005260:Female; D019337:Hematologic Neoplasms / Q000150:complications / Q000628:therapy*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006470:Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D008297:Male; D015080:Mesna / Q000008:administration & dosage
chemical_list: D003520:Cyclophosphamide; D015080:Mesna