title: [Spiral CT angiography in stenoses of the middle cerebral artery].
abstract: BACKGROUND
  Transcranial Doppler ultrasonography (TCD) and magnetic resonance angiography (MRA) are well-established techniques for ascertaining intracranial obstructive artery disease. The short examination time required for additional helical CT angiography (CTA) allows quick management of emergency patients already undergoing native CT. However, today the ability of CTA to detect stenoses of the middle cerebral artery (MCA) has not been proven. To analyse the value of CTA in the classification of atherosclerotic disease 23 MCA stenoses confirmed by TCD and MRA were investigated.
  
  
  METHODS
  CTA was performed on a Hispeed advantage scanner (GE) using a bolus injection of 70 ml KM and 40 ml NaCl with a flow rate of 2.5 ml/s, a thickness of 1 mm, a pitch of 1.5 and a 1 mm increment. CTA was presented as maximum intensity projection (MIP) and as multi-projection volume reconstruction (MPVR). A three-step classification of stenosis was compared with the results of TCD and MRA.
  
  
  RESULTS
  Good opacification of the MCA was achieved in M1 and M2 segments in all patients. Classification of stenosis by CTA agreed with MRA and TCD in 14 cases; 7 stenoses were assigned to a lower classification by CTA. Two low-grade stenoses could not be proven by CTA. Although MIP and MPVR yield the same result in stenosis classification MPVR showed a sharper image quality. In contrast to MRA, veins were highly opacified in CTA. Artery and vein were sometimes superimposed, which had to be avoided by changing the projection angle.
  
  
  CONCLUSIONS
  Medium- and high-grade MCA stenoses can be demonstrated by CTA quickly and reliably. Compared to MRA and TCD, CTA provides lower grading of stenosis.
authors.affiliation: Institut für Klinische Radiologie, Klinikum der Stadt Mannheim, Fakultät für Klinische Medizin Mannheim, Universität Heidelberg.
authors.forename: K J
authors.initials: KJ
authors.lastname: Lehmann
authors.forename: K W
authors.initials: KW
authors.lastname: Neff
authors.forename: S
authors.initials: S
authors.lastname: Ries
authors.forename: A
authors.initials: A
authors.lastname: Sommer
authors.forename: W
authors.initials: W
authors.lastname: Steinke
authors.forename: M
authors.initials: M
authors.lastname: Georgi
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology; D002545:Brain Ischemia / Q000145:classification / Q000000981:diagnostic imaging*; D002533:Cerebral Angiography / Q000379:methods*; D002536:Cerebral Arteries / Q000000981:diagnostic imaging*; D002544:Cerebral Infarction / Q000145:classification / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D018810:Magnetic Resonance Angiography; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*; D017585:Ultrasonography, Doppler, Transcranial