Primary infection by HHV-6 variant B associated with a fatal case of hemophagocytic syndrome.
The association of a human herpesvirus 6 primary infection with a fatal case of hemophagocytic syndrome in a 3 month old baby is described. The trigger mechanism of the virus for the clinical syndrome is discussed.
Portolani
M
M
Department of Biomedical Sciences, University of Modena, Italy.
Cermelli
C
C
Meacci
M
M
Pietrosemoli
P
P
Pecorari
M
M
Sabbatini
A M
AM
Leoni
S
S
Guerra
A
A
Bonaccorsi
G
G
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D002478:Cells, Cultured; D002522:Chlorocebus aethiops; D004279:DNA, Viral / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005347:Fibroblasts; D006564:Herpesviridae / Q000276:immunology; D015654:Herpesvirus 6, Human / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D015616:Histiocytosis, Non-Langerhans-Cell / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis; D007075:Immunoglobulin M / Q000032:analysis; D007223:Infant; D016133:Polymerase Chain Reaction; D014709:Vero Cells
D000914:Antibodies, Viral; D004279:DNA, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M