[Metallonucleoliposome complexes as a vehicle for gene delivery to mouse skeletal muscles in vivo].
A simple new method for preparing plasmid DNA and preformed zwitterionic liposome complexes is proposed. The ability of these metallonucleoliposome complexes to serve as a vehicle for gene delivery to mammalian cells in vivo was studied. A high level of expression of the reporter gene introduced was observed in mouse skeletal muscles in vivo.
Kovalenko
D V
DV
Shafei
R A
RA
Zelenina
I A
IA
Semenova
M L
ML
Samuilova
O V
OV
Zhdanov
R I
RI
D000818:Animals; D004247:DNA / Q000235:genetics*; D005786:Gene Expression Regulation / Q000502:physiology; D017930:Genes, Reporter; D008081:Liposomes; D008274:Magnesium; D051379:Mice; D018482:Muscle, Skeletal / Q000502:physiology*; D010957:Plasmids / Q000235:genetics*; D014162:Transfection
D008081:Liposomes; D004247:DNA; D008274:Magnesium