[Trypsinogen as a modifier of peptidergic influences on the secretion of the gastric and pancreatic glands].
I.v. administration of trypsinogen potentiated the pentagastrin-induced secretion of gastric glands and reduced the leu-enkephalin effect upon them in the fistula dogs. Intraperitoneal administration of trypsinogen enhanced the pepsinogen synthesis by the gastric glands, did not change the hydrolases activity in pancreas homogenate in rats.
Korot'ko
G F
GF
Aleĭnik
V A
VA
Kurzanov
A N
AN
Khamrakulov
Sh Kh
ShKh
D000818:Animals; D004285:Dogs; D004743:Enkephalin, Leucine / Q000494:pharmacology; D005750:Gastric Juice / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism; D005753:Gastric Mucosa / Q000187:drug effects* / Q000378:metabolism; D010179:Pancreas / Q000187:drug effects* / Q000378:metabolism; D010418:Pentagastrin / Q000494:pharmacology; D051381:Rats; D018000:Receptors, Peptide / Q000187:drug effects* / Q000502:physiology; D013268:Stimulation, Chemical; D014362:Trypsinogen / Q000494:pharmacology*
D018000:Receptors, Peptide; D004743:Enkephalin, Leucine; D014362:Trypsinogen; D010418:Pentagastrin