The American experience with transplantation for acute liver failure.
Liver transplantation has become the major therapy for acute liver failure (ALF) in the United States. Survival rates range from 46% to 89%. Appropriate patient selection, timely referral, and management of common complications have improved survival. Donor organ shortage may prompt further use of extracorporeal support systems and auxillary transplantation in the future. This article reviews the American experience of liver transplantation in patients with ALF.
McCashland
T M
TM
Department of Internal Medicine, University of Nebraska Medical Center, Omaha 68198-3280, USA.
Shaw
B W
BW
Tape
E
E
D000075202:Contraindications; D004630:Emergencies; D006501:Hepatic Encephalopathy / Q000209:etiology / Q000601:surgery; D006801:Humans; D017114:Liver Failure, Acute / Q000401:mortality / Q000601:surgery / Q000628:therapy; D016031:Liver Transplantation / Q000401:mortality; D018579:Patient Selection; D015996:Survival Rate; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology