Outline and discussion points of guidance for repeated dose tissue distribution studies.
Awazu
S
S
Department of Pharmaceutical Science, Tokyo College of Pharmacy, Japan.
Ohno
Y
Y
Shindo
H
H
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D017408:Guidelines as Topic; D007564:Japan; D009928:Organ Specificity; D010599:Pharmacokinetics; D014018:Tissue Distribution / Q000187:drug effects; D014116:Toxicology / Q000592:standards*