title: [A case of solitary splenic metastasis from colon cancer].
abstract: A 58-year-old male who had a left hemicolectomy for descending colon cancer on July 1, 1993 was admitted to our hospital. A CT scan revealed a homogeneous low-density mass in the inferior portion of the spleen. Under the diagnosis of solitary splenic metastasis, a splenectomy was performed on August 10, 1995. Histologically, splenic tumor revealed moderately differentiated adenocarcinoma consistent with the primary tumor. Flow cytometric analysis revealed DNA diploidy in the primary tumor, and DNA aneuploidy (DNA index = 1.76) in the metastatic tumor. Using fluorescence in situ hybridization with p17 H8, numerical aerrations of chromosome 17 were observed in the primary tumor.
authors.affiliation: First Department of Surgery, Nagasaki University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Sawai
authors.forename: T
authors.initials: T
authors.lastname: Nakagoe
authors.forename: Y
authors.initials: Y
authors.lastname: Tagawa
authors.forename: O
authors.initials: O
authors.lastname: Sasano
authors.forename: H
authors.initials: H
authors.lastname: Yamaguchi
authors.forename: T
authors.initials: T
authors.lastname: Yasutake
authors.forename: H
authors.initials: H
authors.lastname: Kusano
authors.forename: H
authors.initials: H
authors.lastname: Ayabe
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics / Q000556:secondary* / Q000601:surgery; D000782:Aneuploidy; D003082:Colectomy; D003110:Colonic Neoplasms / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D004273:DNA, Neoplasm / Q000235:genetics; D004171:Diploidy; D006801:Humans; D008297:Male; D008875:Middle Aged; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000235:genetics / Q000556:secondary* / Q000601:surgery
chemical_list: D004273:DNA, Neoplasm