A system to analyze and identify inhibitors of HIV-1 gene regulation using a defective integrated provirus.
Byrnes
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Department of Antiviral Research, Merck Research Laboratories, West Point, Pennsylvania 19486, USA.
Hazuda
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D000818:Animals; D001483:Base Sequence; D019556:COS Cells; D003001:Cloning, Molecular / Q000379:methods; D003673:Defective Viruses / Q000235:genetics / Q000502:physiology*; D015967:Gene Expression Regulation, Viral; D015696:Gene Products, tat / Q000096:biosynthesis; D017930:Genes, Reporter; D015756:Genes, tat; D016679:Genome, Viral; D015497:HIV-1 / Q000235:genetics / Q000502:physiology*; D006801:Humans; D019169:Jurkat Cells; D008156:Luciferases / Q000096:biosynthesis; D008969:Molecular Sequence Data; D016376:Oligonucleotides, Antisense; D011533:Proviruses / Q000235:genetics / Q000502:physiology; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis; D015533:Transcriptional Activation; D014162:Transfection / Q000379:methods; D016662:Virus Integration; D054322:tat Gene Products, Human Immunodeficiency Virus
D015696:Gene Products, tat; D016376:Oligonucleotides, Antisense; D011993:Recombinant Fusion Proteins; D054322:tat Gene Products, Human Immunodeficiency Virus; D008156:Luciferases