title: Slow coronary run-off in patients with angina pectoris: clinical significance and thallium-201 scintigraphic study.
abstract: To determine whether or not slow coronary flow (SF) depends on hemodynamic variables, we studied 17 patients (15 men, mean age = 47.8 years) with SF at coronariography. Exercise thallium-201 myocardial scintigraphy revealed perfusion abnormalities in 13 (76.4%) patients. We then selected 89 individuals submitted to cinecoronariography for comparison: 15 were normal and 74 had heart disease. The coronary flow velocity was evaluated by the number of heart beats (HB) needed for coronary artery dye filling. The patients in the SF group had normal hemodynamic variables which were significantly different from those of patients with heart disease (P = 0.001). Patients with heart disease needed no more than 4 HB to fill their arteries, in contrast to 6.88 +/- 1.68 (5 to 11) in the SF group (P < 0.0001). Thus, in our patients with myocardial scintigraphy suggesting ischemia, SF was found to be an event which did not depend on hemodynamic factors.
authors.affiliation: Instituto do Coração, Faculdade de Medicina, Universidade de São Paulo, Brasil.
authors.forename: L A
authors.initials: LA
authors.lastname: César
authors.forename: J A
authors.initials: JA
authors.lastname: Ramires
authors.forename: C V
authors.initials: CV
authors.lastname: Serrano Júnior
authors.forename: J C
authors.initials: JC
authors.lastname: Meneghetti
authors.forename: R H
authors.initials: RH
authors.lastname: Antonelli
authors.forename: P L
authors.initials: PL
authors.lastname: da-Luz
authors.forename: F J
authors.initials: FJ
authors.lastname: Pileggi
mesh_terms: D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D000787:Angina Pectoris / Q000000981:diagnostic imaging*; D001783:Blood Flow Velocity / Q000502:physiology; D003326:Coronary Circulation / Q000502:physiology*; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D005260:Female; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013794:Thallium Radioisotopes
chemical_list: D013794:Thallium Radioisotopes