[The action of piracetam and its complex with sodium oxybutyrate in the neuropathic pain syndrome].
Effects of the pyracetam and its sodium hydroxybutyrate complex were studied on a model of the neuropathic pain syndrome. It was demonstrated that the pyracetam prevents the development of the neuropathic pain syndrome. The pyracetam relieves the pain syndrome. The sodium hydroxybutyrate appears to enhance preventive and medical effects of the pyracetam. Possible mechanisms of action of these drugs are discussed.
Danilova
E I
EI
Grafova
V N
VN
Reshetniak
V K
VK
D000818:Animals; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D010146:Pain / Q000209:etiology / Q000517:prevention & control*; D017288:Pain Threshold / Q000187:drug effects; D010889:Piracetam / Q000494:pharmacology / Q000627:therapeutic use*; D051381:Rats; D012978:Sodium Oxybate / Q000494:pharmacology / Q000627:therapeutic use*; D013577:Syndrome; D013997:Time Factors
D012978:Sodium Oxybate; D010889:Piracetam