[Hemostasis in patients with diabetes mellitus. II. Tissue factor and the extrinsic blood coagulation inhibitor].
In the submitted pilot study we examined 37 patients suffering from diabetes mellitus without vascular complications and 15 healthy blood donors. The diabetic patients had not, as compared with the blood donors, significantly elevated values of the tissue factor (TF) and tissue factor pathway inhibitor (TFPI). The TFPI levels correlated with other markers of endothelial dysfunction, in particular thrombomodulin (r = 0.452, p < 0.01) and with triacylglycerol and cholesterol levels. They did not correlate with age, the C-peptide level and BMI.
Galajda
P
P
I. interná klinika, MFN Martin.
Martinka
E
E
Kubisz
P
P
Ivanková
J
J
Ochodnický
M
M
Polko
J
J
Mokán
M
M
D000328:Adult; D003920:Diabetes Mellitus / Q000097:blood*; D065427:Factor Xa Inhibitors; D005260:Female; D006487:Hemostasis; D006801:Humans; D008074:Lipoproteins / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D015842:Serine Proteinase Inhibitors / Q000097:blood*; D013925:Thromboplastin / Q000032:analysis*; D014841:von Willebrand Factor / Q000032:analysis
D065427:Factor Xa Inhibitors; D008074:Lipoproteins; D015842:Serine Proteinase Inhibitors; C051928:lipoprotein-associated coagulation inhibitor; D014841:von Willebrand Factor; D013925:Thromboplastin