Novel methods of generating specific oligonucleotide inhibitors of viral polymerases.
Chen
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H
Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder 80309, USA.
Brown
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D
Gold
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L
D001483:Base Sequence; D017931:DNA Primers; D004926:Escherichia coli / Q000201:enzymology; D054303:HIV Reverse Transcriptase / Q000037:antagonists & inhibitors*; D015497:HIV-1 / Q000201:enzymology; D006801:Humans; D007700:Kinetics; D008024:Ligands; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D009843:Oligoribonucleotides / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D016133:Polymerase Chain Reaction / Q000379:methods; D011777:Q beta Replicase / Q000378:metabolism; D012313:RNA / Q000096:biosynthesis / Q000737:chemistry; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism*; D018894:Reverse Transcriptase Inhibitors / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology; D013698:Templates, Genetic
D017931:DNA Primers; D008024:Ligands; D009838:Oligodeoxyribonucleotides; D009843:Oligoribonucleotides; D018894:Reverse Transcriptase Inhibitors; D012313:RNA; D011777:Q beta Replicase; D054303:HIV Reverse Transcriptase; D012194:RNA-Directed DNA Polymerase