Current status of retinoids in chemoprevention of oral squamous cell carcinoma: an overview.
Squamous cell carcinoma of the oral cavity and oropharynx may be amenable to chemoprevention. This review focuses on current concepts of mechanisms in oral carcinogenesis, as well as the evidence that retinoids have a role in the primary and secondary prevention of this malignancy.
Conley
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BA
Department of Medicine (Division of Haematology-Oncology), University of Maryland Cancer Center, Baltimore, USA.
Ord
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RA
D016588:Anticarcinogenic Agents / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000209:etiology / Q000517:prevention & control*; D018890:Chemoprevention; D006801:Humans; D007972:Leukoplakia, Oral / Q000517:prevention & control; D009062:Mouth Neoplasms / Q000209:etiology / Q000517:prevention & control*; D016609:Neoplasms, Second Primary / Q000517:prevention & control; D009959:Oropharyngeal Neoplasms / Q000209:etiology / Q000517:prevention & control; D012176:Retinoids / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use*
D016588:Anticarcinogenic Agents; D012176:Retinoids