[The role of genetically determined oxidation of drugs and xenobiotics in pathogenesis of neoplastic diseases].
The relationship between genetically determined polymorphic hepatic oxidation and susceptibility to neoplastic diseases have aroused much interest. Some studies provide evidence of a possible association between oxidation phenotype, especially extensive and very extensive phenotype, and increased risk of the development of cancers. This work presents modern views on that subject.
Niewiński
P
P
Katedra i Zakład Farmakologii Klinicznej Akademii Medycznej we Wrocławiu.
Orzechowska-Juzwenko
K
K
D004198:Disease Susceptibility; D006801:Humans; D008099:Liver / Q000378:metabolism*; D006899:Mixed Function Oxygenases / Q000235:genetics*; D009369:Neoplasms / Q000235:genetics*; D010084:Oxidation-Reduction; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010641:Phenotype; D012307:Risk Factors; D015262:Xenobiotics / Q000378:metabolism*
D004364:Pharmaceutical Preparations; D015262:Xenobiotics; D006899:Mixed Function Oxygenases