title: Anogenital lichen sclerosus in women.
abstract: A study of 350 women with lichen sclerosus, originally made to elucidate the relationship between lichen sclerosus and autoimmunity, led to the amassing of a considerable amount of clinical material. Our review is confined to those with anogenital lesions (342), supplemented by some new cases (15), giving a total of 357 women with biopsy proven lichen sclerosus. It demonstrates the wide age range of the condition, the association with morphoea and lichen planus and the occurrence of squamous cell carcinoma in some cases. It also shows that inappropriate surgery has continued to be carried out for benign disease.
authors.affiliation: Salisbury District Hospital, Wiltshire, England.
authors.forename: R H
authors.initials: RH
authors.lastname: Thomas
authors.forename: C M
authors.initials: CM
authors.lastname: Ridley
authors.forename: D H
authors.initials: DH
authors.lastname: McGibbon
authors.forename: M M
authors.initials: MM
authors.lastname: Black
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001004:Anus Diseases / Q000150:complications* / Q000209:etiology / Q000628:therapy; D001327:Autoimmune Diseases / Q000150:complications; D002294:Carcinoma, Squamous Cell / Q000209:etiology; D005260:Female; D006801:Humans; D018459:Lichen Sclerosus et Atrophicus / Q000150:complications* / Q000209:etiology / Q000628:therapy; D008875:Middle Aged; D014845:Vulvar Diseases / Q000150:complications* / Q000209:etiology / Q000628:therapy; D014846:Vulvar Neoplasms / Q000209:etiology