title: Non-fibrous inorganic particles in bronchoalveolar lavage fluid of pottery workers.
abstract: OBJECTIVE
  To study the actual exposure of pottery workers to silica particles, as their risk of silicosis is potentially high because of the presence of inhalable crystalline silica particles in the workplace.
  
  
  METHODS
  Nine pottery workers underwent bronchoalveolar lavage. The recovered fluid was analysed for cytological and mineralogical content by analytical transmission electron microscopy. The data were compared with those obtained from a control group composed of seven patients with sarcoidosis and six patients with haemoptysis.
  
  
  RESULTS
  Cytological results showed a similar profile in exposed workers and controls, whereas in patients with sarcoidosis a lymphocytic alveolitis was found. Microanalysis of the particulate identified the presence of silicates, CRSs, and metals. Pottery workers had higher numbers of total particles and CRSs, and had a higher silicate/metal ratio. In five workers, the presence of zirconium silicate was also detected. Patients with sarcoidosis had the lowest number of particles, and an inverted silicate/metal ratio.
  
  
  CONCLUSIONS
  Microanalysis by transmission electron microscope can provide useful information to assess occupational exposure to dusts.
authors.affiliation: Department of Ultrastructures, Istituto Superiore di Sanità, Roma, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Falchi
authors.forename: L
authors.initials: L
authors.lastname: Paoletti
authors.forename: S
authors.initials: S
authors.lastname: Mariotta
authors.forename: S
authors.initials: S
authors.lastname: Giosue
authors.forename: L
authors.initials: L
authors.lastname: Guidi
authors.forename: L
authors.initials: L
authors.lastname: Biondo
authors.forename: P
authors.initials: P
authors.lastname: Scavalli
authors.forename: A
authors.initials: A
authors.lastname: Bisetti
mesh_terms: D000328:Adult; D000368:Aged; D018893:Bronchoalveolar Lavage; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry*; D016022:Case-Control Studies; D004391:Dust / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D008670:Metals / Q000032:analysis*; D008854:Microscopy, Electron; D008875:Middle Aged; D016273:Occupational Exposure / Q000032:analysis*; D013902:Radiography, Thoracic; D017640:Silicates / Q000032:analysis; D012822:Silicon Dioxide / Q000032:analysis*; D015040:Zirconium / Q000032:analysis
chemical_list: D004391:Dust; D008670:Metals; D017640:Silicates; D012822:Silicon Dioxide; D015040:Zirconium