title: Reconstruction of massive bone defects with allograft in revision total knee arthroplasty.
abstract: Allograft bone was used to reconstruct a defect in the proximal aspect of the tibia or the distal aspect of the femur, or both, in thirty knees of twenty-eight patients who had a revision total knee arthroplasty. The average age of the patients at the time of the index procedure was 65.8 years (range, twenty-four to eighty-nine years). At an average of fifty months (range, twenty-four to 132 months; median, thirty-six months) postoperatively, the score for twenty-three knees (twenty-one patients) had increased by at least 20 points, and these knees did not need additional operative treatment. Thus, the rate of success was 77 per cent. The procedure was considered a failure for the remaining seven knees because of infection (three), loosening of the tibial component (two), fracture of the graft (one), and non-union at the allograft-host junction (one). Properly applied allograft can be used to reconstruct massive bone defects, provide stability and support for implants, and restore bone stock in the event that additional operative treatment is necessary.
authors.affiliation: University of Toronto, Ontario, Canada.
authors.forename: M T
authors.initials: MT
authors.lastname: Ghazavi
authors.forename: I
authors.initials: I
authors.lastname: Stockley
authors.forename: G
authors.initials: G
authors.lastname: Yee
authors.forename: A
authors.initials: A
authors.lastname: Davis
authors.forename: A E
authors.initials: AE
authors.lastname: Gross
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016025:Bone Transplantation; D005260:Female; D005269:Femur / Q000601:surgery; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D019736:Prostheses and Implants; D011475:Prosthesis Failure; D012086:Reoperation; D013977:Tibia / Q000601:surgery; D014184:Transplantation, Homologous