[Erythrocytapheresis a few weeks before surgery: an alternative to erythropoietin treatment in programmed autologous transfusion].
The usual methods like hypotension, isovolaemic haemodilution, autologous transfusion and peri-operative blood salvage may significantly reduce the need for homologous blood transfusion in haemorrhagic surgery and also the risk of transmitting infectious agents. Erythropoietin (EPO) is now available and is used to stimulate red cell regeneration in pre-operative autologous blood donation. In acute anaemia, many studies have shown that the stimulation of endogenous erythropoietin production could be very high and accelerate red blood cell production. Taking higher quantities of blood than usual induces a secretion of endogenous erythropoietin, and could be an alternative for the utilization of exogenous EPO in autologous blood donation.
Bernière
J
J
Département Anesthésiologie, Hôpital Trousseau, Paris.
Gerota
I
I
D001804:Blood Transfusion, Autologous; D003362:Cost-Benefit Analysis; D016238:Cytapheresis / Q000379:methods*; D017707:Erythrocyte Transfusion; D004920:Erythropoiesis / Q000502:physiology; D004921:Erythropoietin / Q000097:blood* / Q000627:therapeutic use; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D011300:Preoperative Care / Q000379:methods
D006454:Hemoglobins; D004921:Erythropoietin