Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): report of a patient with isolated renotesticular involvement after cure of non-Hodgkin's lymphoma.
Sinus histiocytosis with massive lymphadenopathy (SHML)-Rosai-Dorfman disease-is a rare but well-defined benign histiocytic proliferative disorder. We report an unusual patient, cured of non-Hodgkin's lymphoma, who presented 12 years later with renotesticular SHML associated with IgA monoclonal gammopathy, but without any evidence of relapsed lymphoma. The genitourinary manifestations of this disorder with massive lymphadenopathy and its rare association with malignant lymphoma are reviewed.
Lossos
I S
IS
Department of Hematology, Hadassah University Hospital, Jerusaelm, Israel.
Okon
E
E
Bogomolski-Yahalom
V
V
Ron
N
N
Polliack
A
A
D000328:Adult; D000368:Aged; D002648:Child; D015618:Histiocytosis, Sinus / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007124:Immunoenzyme Techniques; D007674:Kidney Diseases / Q000209:etiology; D008228:Lymphoma, Non-Hodgkin / Q000628:therapy; D008297:Male; D008875:Middle Aged; D013733:Testicular Diseases / Q000209:etiology; D013737:Testis / Q000473:pathology; D013997:Time Factors