Primary carcinoma of the fallopian tube: report on two cases.
Two cases of carcinoma of the Fallopian tube were treated by total abdominal hysterectomy, bilateral salpingo-oophorectomy and omentectomy followed by chemotherapy consisting of several courses of a cisplatin, epirubicin and cyclophosphamide combination. One patient received three additional courses of combined cisplatin-taxol. At 60 months from onset of therapy one patient (Stage IIa-Grade 1 tumor) is alive and well, while the other (Stage III-Grade 3 tumor) died of disease 26 months from initial treatment. Second-look laparotomy proved useful in assessing response to chemotherapy. CA-125 blood levels helped monitoring tumor activity. Anamnestic data relevant to tuberculous salpingitis on one case, and bilateral salpingoplasty for tubal occlusion, in the other case, may stand for some remarks.
Nappi
R
R
Institute of Gynecology and Obstetrics, University of Bari, Italy.
Resta
L
L
Nappi
L
L
Loizzi
P
P
D000230:Adenocarcinoma / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D000231:Adenocarcinoma, Papillary / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D018394:CA-125 Antigen / Q000032:analysis; D002945:Cisplatin / Q000627:therapeutic use; D005185:Fallopian Tube Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D017239:Paclitaxel / Q000627:therapeutic use
D018394:CA-125 Antigen; D017239:Paclitaxel; D002945:Cisplatin