title: Intravenous MRI contrast enhancement of inflammatory synovium: a dose study.
abstract: A dose study was performed of MRI intravenous contrast medium enhancement of rheumatoid synovium in the knee, comparing the enhancement with gadoteridol at doses of 0.1 and 0.3 mmol/kg. A measurable and significant difference was demonstrated which has particular relevance to the accuracy of dose calculations needed when performing quantitative studies.
authors.affiliation: Department of Radiology, Bristol Royal Infirmary, UK.
authors.forename: C
authors.initials: C
authors.lastname: Oliver
authors.forename: I
authors.initials: I
authors.lastname: Watt
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000175:diagnosis / Q000473:pathology; D003287:Contrast Media / Q000008:administration & dosage; D004305:Dose-Response Relationship, Drug; D005260:Female; D005682:Gadolinium / Q000008:administration & dosage; D006571:Heterocyclic Compounds / Q000008:administration & dosage*; D006801:Humans; D007275:Injections, Intravenous; D007719:Knee Joint; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds / Q000008:administration & dosage*; D013585:Synovitis / Q000175:diagnosis*
chemical_list: D003287:Contrast Media; D006571:Heterocyclic Compounds; D009942:Organometallic Compounds; C062402:gadoteridol; D005682:Gadolinium