[Histamine liberation (or histamine release HR): study of the positivity threshold in hymenoptera venom allergy].
Dialysis of Hymenoptera venoms for measurement of HR by the radioimmunoassay technique (RIA, Immunotech) lowers the threshold of positivity of the HR titre from 30% to 12%. This modification of dialysis of the venoms significantly improves the sensitivity and specificity of the technique.
Minkhar
M
M
Laboratoire d'Immuno-Allergologie, CHU, Angers.
Giffard
G
G
Lauret
M G
MG
Hassoun
S
S
Drouet
M
M
Sainte-Laudy
J
J
Sabbah
A
A
D001514:Bee Venoms / Q000276:immunology / Q000302:isolation & purification / Q000494:pharmacology*; D003956:Dialysis; D004306:Dose-Response Relationship, Immunologic; D006636:Histamine Release / Q000187:drug effects*; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000209:etiology / Q000276:immunology*; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D007428:Intradermal Tests; D011863:Radioimmunoassay; D012680:Sensitivity and Specificity; D014862:Wasp Venoms / Q000276:immunology / Q000302:isolation & purification / Q000494:pharmacology*
D001514:Bee Venoms; D014862:Wasp Venoms; D007073:Immunoglobulin E