title: Prognostic value of contrast enhanced Gd-DTPA MRI for development of bone erosive changes in rheumatoid arthritis.
abstract: Conventional radiograms have been used to quantitate the progression of rheumatoid arthritis, mainly through the assessment of bone erosions, but this approach has many limitations. It has been suggested that an advantage of contrast-enhanced Gd-DTPA MRI over radiography may be its prognostic value due to its ability to show the natural history of active destructive to inactive fibrous pannus. The aim of this study was to evaluate the possible prognostic value of MRI for future development of bone erosive changes in small hand joints in patients with RA. The results of the study confirm that in joints in which inflammatory active pannus is shown by contrast-enhanced MRI, progression of bone-destructive changes can be expected.
authors.affiliation: Radiology Institute, University Medical Centre Ljubljana, Slovenia.
authors.forename: V
authors.initials: V
authors.lastname: Jevtic
authors.forename: I
authors.initials: I
authors.lastname: Watt
authors.forename: B
authors.initials: B
authors.lastname: Rozman
authors.forename: M
authors.initials: M
authors.lastname: Presetnik
authors.forename: D
authors.initials: D
authors.lastname: Logar
authors.forename: S
authors.initials: S
authors.lastname: Praprotnik
authors.forename: M
authors.initials: M
authors.lastname: Tomsic
authors.forename: A
authors.initials: A
authors.lastname: Sipek
authors.forename: M
authors.initials: M
authors.lastname: Kos-Golja
authors.forename: A
authors.initials: A
authors.lastname: Sepe
authors.forename: O
authors.initials: O
authors.lastname: Jarh
authors.forename: F
authors.initials: F
authors.lastname: Demsar
authors.forename: P
authors.initials: P
authors.lastname: Musikic
authors.forename: G
authors.initials: G
authors.lastname: Campion
mesh_terms: D001172:Arthritis, Rheumatoid / Q000503:physiopathology*; D001862:Bone Resorption / Q000503:physiopathology*; D003287:Contrast Media; D004311:Double-Blind Method; D005260:Female; D005682:Gadolinium; D019786:Gadolinium DTPA; D006225:Hand / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives*; D011379:Prognosis; D011446:Prospective Studies; D011859:Radiography; D014953:Wrist / Q000000981:diagnostic imaging / Q000473:pathology
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA