title: Efficacy of tissue plasminogen activator (t-PA) in subretinal hemorrhage removal.
abstract: t-PA can be used intra-operatively to liquify a large and elevated submacular blood clot and to facilitate the aspiration through a small retinotomy. In 15 consecutive patients we operated in this way, we noticed that an intra-operative subretinal injection of t-PA was never able to dissolve the blood clot completely. Therefore it was necessary to perform a large retinotomy in large hemorrhages.
authors.affiliation: Dienst Oogziekten, AZ Middelheim, Antwerpen.
authors.forename: C
authors.initials: C
authors.lastname: Claes
authors.forename: R
authors.initials: R
authors.lastname: Zivojnovic
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008268:Macular Degeneration / Q000150:complications; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic; D012166:Retinal Hemorrhage / Q000150:complications / Q000188:drug therapy*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D010959:Tissue Plasminogen Activator