title: [Rotavirus: clinical and epidemiological study in hospitalized children under two years of age].
abstract: OBJECTIVE
  Rotavirus (RV) remains as the leading cause of acute diarrheal disease in early infancy; nevertheless, there are few epidemiological studies in our geographical area. In order to better understand the clinical epidemiology of RV, we have carried out a revision of acute diarrheal illnesses in the area of Santiago de Compostela (Spain) in children younger than 2 years of age who needed hospitalization during a 12 month period.
  
  
  METHODS
  In 155 children with suspected gastroenteritis, 339 stool samples were collected and separated into two groups depending upon the presence or not of RV antigen.
  
  
  RESULTS
  In the group of RV-positive stool patients, the occurrence of vomiting, fever, need of intravenous fluid rehydration (p = 0.01), respiratory symptoms (p < 0.01), the incidence during winter, as well as the development of disaccharidase depression (p < 0.001), were more frequent as compared with the group of children of similar age who did not present RV in faeces. There was no difference between the two groups regarding the presence of other potential enteropathogen agents (p > 0.05). The incidence of RV-positive faeces per 100 hospitalized infants/year was 10.5 and that of infants with RV diarrhea who needed hospitalization was 5.5%/ year.
  
  
  CONCLUSIONS
  There was no mortality related with gastroenteritis, but RV-infection remains an important cause of morbidity and socioeconomic burden. Nosocomially acquired hospital infections add to morbidity and the cost of hospitalization.
authors.affiliation: Departamento de Pediatría, Hospital General de Galicia, Facultad de Medicina, Santiago de Compostela.
authors.forename: J
authors.initials: J
authors.lastname: Rodríguez Cervilla
authors.forename: M D
authors.initials: MD
authors.lastname: Peñalver Barral
authors.forename: M C
authors.initials: MC
authors.lastname: Curros Novo
authors.forename: P
authors.initials: P
authors.lastname: Pavón Belinchón
authors.forename: C
authors.initials: C
authors.lastname: Alonso Alonso
authors.forename: J M
authors.initials: JM
authors.lastname: Fraga
mesh_terms: D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology / Q000821:virology*; D006760:Hospitalization; D006776:Hospitals, Pediatric; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D012401:Rotavirus / Q000302:isolation & purification*; D013030:Spain / Q000453:epidemiology