title: [Study of choroidal vascular lesions in central serous chorioretinopathy using indocyanine green angiography].
abstract: We performed fluorescein and indocyanine green (ICG) angiographies in 56 patients with central serous chorioretinopathy, and studied the choroidal lesions. In the early phase, choroidal filling with ICG was delayed in 77% in the area including focal leakage. Hypofluorescent findings around the site of focal leakage persisted through the phase in 23%, and we think this finding was caused by filling defect of the choriocapillaris. In the late phase, choroidal tissue staining by ICG was present in 82% in the area including focal leakage. Multiple areas of choroidal staining were also present in unaffected areas in 43% and in 62% of fellow eyes. Choroidal tissue staining by ICG was revealed in 48% in the area of choroidal filling delay, and this finding persisted after focal leakage had disappeared following photocoagulation. We think this finding was caused by choroidal vascular hyperpermeability. These findings suggest that choroidal circulatory disturbance and choroidal vascular hyperpermeability play a causative role in damage to the retinal pigment epithelium in central serous chorioretinopathy.
authors.affiliation: Department of Ophthalmology, Sapporo City General Hospital, Hokkaido, Japan.
authors.forename: U
authors.initials: U
authors.lastname: Okushiba
authors.forename: M
authors.initials: M
authors.lastname: Takeda
mesh_terms: D000328:Adult; D002829:Choroid / Q000098:blood supply*; D015862:Choroid Diseases / Q000473:pathology*; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000473:pathology*
chemical_list: D007208:Indocyanine Green