title: [The prenatal cytogenetic diagnosis of fetal chromosomal pathology in women in a high-risk group].
abstract: The results of investigation of 908 chorion and placental biopsy in 873 pregnant women of high risk a group is presented. Fetal pathology was diagnosed with the help of "direct" method and shot-term method of culture of chorionic villi and placenta, as well as method of long-term fetal lymphocyte cultures. The efficiency of invasive methods of prenatal diagnosis, and their role in decrease of perinatal disease and mortality was confirmed.
authors.forename: T V
authors.initials: TV
authors.lastname: Nikitchyna
authors.forename: I R
authors.initials: IR
authors.lastname: Baryliak
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Hordiienko
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy / Q000706:statistics & numerical data; D015193:Chorionic Villi Sampling / Q000706:statistics & numerical data; D002869:Chromosome Aberrations / Q000175:diagnosis*; D025063:Chromosome Disorders; D017218:Cordocentesis / Q000706:statistics & numerical data; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D010920:Placenta / Q000473:pathology; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000706:statistics & numerical data; D012307:Risk Factors