Development of malignant melanoma after repeated topical photodynamic therapy with 5-aminolevulinic acid at the exposed site.
We report the case of a 82-year-old man who, after multiple treatments with aminolevulinic acid photodynamic therapy for solar keratoses and superficial squamous cell carcinomas, developed malignant melanoma at the exposed site on the scalp.
Wolf
P
P
Department of Dermatology, University of Graz, Austria.
Fink-Puches
R
R
Reimann-Weber
A
A
Kerl
H
H
D000368:Aged; D000369:Aged, 80 and over; D000505:Alopecia / Q000150:complications; D000622:Aminolevulinic Acid / Q000009:adverse effects*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy; D005500:Follow-Up Studies; D006801:Humans; D007642:Keratosis / Q000188:drug therapy; D008297:Male; D008545:Melanoma / Q000139:chemically induced*; D010778:Photochemotherapy / Q000009:adverse effects*; D017319:Photosensitizing Agents / Q000009:adverse effects*; D012535:Scalp / Q000187:drug effects*; D012878:Skin Neoplasms / Q000139:chemically induced* / Q000188:drug therapy; D013472:Sunlight / Q000009:adverse effects
D017319:Photosensitizing Agents; D000622:Aminolevulinic Acid