[Lipoprotein (a) and plasminogen in atherosclerosis].
The aim of this study was to evaluate plasma levels of lipoprotein (a) [LP(a)] and plasminogen in patients affected with atherosclerotic disease and to understand the mutual relationships. Eighty-four patients affected with atherosclerosis were examined and divided as follows: group I, 24 patients with peripheral arteriopathy; group II, 40 patients with ischemic heart disease (myocardial infarction and/or angina pectoris); group III, 20 patients with multi-infarct dementia; group IV (control group) with 20 healthy young subjects. The results show that Lp(a) plasma levels, in atherosclerotic patients, are higher than 30 mg/dl, while the plasminogen levels are lower than 80 mg/dl. There is an inverse correlation between these two data. Moreover, a different behaviour of Lp(a) and plasminogen rate related to age of patients, to number of atherosclerotic lesions or to acuteness of ischemic heart disease, was observed.
Danese
C
C
Università degli Studi di Roma, La Sapienza, Il Istituto Clinica Medica.
Borgia
M C
MC
Ferranti
E
E
Zavattaro
E
E
Epiceno
A N
AN
Marcianó
F
F
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000097:blood; D001157:Arterial Occlusive Diseases / Q000097:blood; D001161:Arteriosclerosis / Q000097:blood*; D003124:Colorimetry; D003327:Coronary Disease / Q000097:blood; D003627:Data Interpretation, Statistical; D015161:Dementia, Multi-Infarct / Q000097:blood; D006801:Humans; D007124:Immunoenzyme Techniques; D017270:Lipoprotein(a) / Q000097:blood*; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood; D010958:Plasminogen / Q000032:analysis*
D017270:Lipoprotein(a); D010958:Plasminogen