title: CTLA-4, a negative regulator of T-lymphocyte activation.
authors.affiliation: Ontario Cancer Institute, Department of Medical Biophysics, University of Toronto, Canada.
authors.forename: P
authors.initials: P
authors.lastname: Waterhouse
authors.forename: L E
authors.initials: LE
authors.lastname: Marengère
authors.forename: H W
authors.initials: HW
authors.lastname: Mittrücker
authors.forename: T W
authors.initials: TW
authors.lastname: Mak
mesh_terms: D000069594:Abatacept; D000595:Amino Acid Sequence; D000818:Animals; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000235:genetics / Q000378:metabolism*; D060908:CTLA-4 Antigen; D006706:Homeostasis; D018796:Immunoconjugates; D007166:Immunosuppressive Agents / Q000378:metabolism*; D008024:Ligands; D008213:Lymphocyte Activation; D051379:Mice; D018448:Models, Immunological; D008969:Molecular Sequence Data; D011485:Protein Binding; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000276:immunology*; D013602:T-Lymphocytes, Cytotoxic
chemical_list: D015703:Antigens, CD; D000943:Antigens, Differentiation; D060908:CTLA-4 Antigen; C556707:Ctla4 protein, mouse; D018796:Immunoconjugates; D007166:Immunosuppressive Agents; D008024:Ligands; D000069594:Abatacept