title: [Methodological aspects and clinicophysiological substantiation of applying the hypoxic therapy].
abstract: The paper gives the methodical and clinicophysiological substantiation of the hypoxic therapy, a new nonmedicamentous method of body sanitation, raising its physiological reserves, prevention of pathological states, treatment and medical rehabilitation of patients based on breathing air with a reduced O2 partial pressure for the purposes. Health damaging and improving effects of hypoxic hypoxia, perspectives of this therapy from the standpoint of prevention and treatment of myocardial ischemia are discussed. Results of the fundamental studies unveiling the mechanisms of ischemic, reperfusion-induced disorders of myocardium and assessing possibilities of their blockage of the hypoxic therapy are considered. On the literary and own evidence, the authors analyse effectiveness, merits and drawbacks of different (mountain/climatic, hypobaric, normobaric) techniques of hypoxic therapy. Informative criteria for determination of hypoxic resistance of the patient with coronary diseases and choice of individual hypoxic regimen are rationalized.
authors.affiliation: Military Medical Academy, Saint-Petersburg.
authors.forename: V S
authors.initials: VS
authors.lastname: Novikov
authors.forename: V V
authors.initials: VV
authors.lastname: Goranchuk
authors.forename: N I
authors.initials: NI
authors.lastname: Sapova
mesh_terms: D006801:Humans; D000860:Hypoxia; D017202:Myocardial Ischemia / Q000628:therapy*; D012138:Respiratory Therapy / Q000379:methods*; D016896:Treatment Outcome