[Amiodarone-induced hypothyroidism followed by hyperthyroidism. Apropos of 2 new cases].
Amiodarone, an iodine-rich benzofuranic derivative, may often induce hyperthyroidism and hypothyroidism. We report two cases of complex dysthyroidism, in which hypothyroidism and then hyperthyroidism alternated: we recall five former observations found in the literature. Their nosologic position and pathophysiologic mechanisms are discussed.
Wilhelm
J M
JM
Service de Médecine, Centre Hospitalier St-Morand, Altkirch.
Saraceni
O
O
Kieffer
P
P
D000368:Aged; D000638:Amiodarone / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000139:chemically induced* / Q000503:physiopathology; D007037:Hypothyroidism / Q000139:chemically induced* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged
D000889:Anti-Arrhythmia Agents; D000638:Amiodarone