[Pregnancy in women undergoing a kidney transplant. Our experience and a review of the literature].
The chances of pregnancy for uremic women are usually very low, because of hormonal balance changes which determine a strong reduction in fertility. Epidemiological studies reveal that pregnancy in hemodialyzed women in fertile patients 4.6-6 months after a well functioning kidney transplant, one fertile transplanted woman over 50 can become pregnant. In the first transplant era, pregnancy after kidney transplant was considered "a big hazard", especially because of the possible side-effects of immunosuppression drugs on foetus development, and the risk of a worsening in the mother's renal function. Therefore, women were strongly recommended to avoid pregnancy. More recently, several reported papers have shown that pregnancy can be safely carried on also by transplanted women, under careful criteria and monitoring. Our experience too, even if limited in number (4 patients) reported in this article confirms this conviction.
Tommasi
G V
GV
Cattedra di Chirurgia Sostitutiva e dei Trapianti d'Organo, Università degli Studi, Genova.
Casolino
V
V
Fontana
I
I
Beatini
M
M
Semino
A
A
Manolitsi
O
O
Dondero
F
F
Valente
U
U
D005260:Female; D006801:Humans; D016030:Kidney Transplantation / Q000502:physiology*; D011184:Postoperative Period; D011247:Pregnancy / Q000502:physiology*; D006435:Renal Dialysis; D013997:Time Factors; D014511:Uremia / Q000628:therapy