title: 3-Heteroarylquinuclidin-2-ene derivatives as muscarinic antagonists: synthesis, structure-activity relationships and molecular modelling.
authors.affiliation: Department of Organic Pharmaceutical Chemistry, Uppsala University, Sweden.
authors.forename: G
authors.initials: G
authors.lastname: Nordvall
authors.forename: B M
authors.initials: BM
authors.lastname: Nilsson
authors.forename: S
authors.initials: S
authors.lastname: Sundquist
authors.forename: G
authors.initials: G
authors.lastname: Johansson
authors.forename: G
authors.initials: G
authors.lastname: Glas
authors.forename: L
authors.initials: L
authors.lastname: Nilvebrant
authors.forename: U
authors.initials: U
authors.lastname: Hacksell
mesh_terms: D000818:Animals; D001665:Binding Sites; D002540:Cerebral Cortex / Q000378:metabolism; D006168:Guinea Pigs; D007700:Kinetics; D008958:Models, Molecular; D008968:Molecular Conformation; D015394:Molecular Structure; D018727:Muscarinic Antagonists / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D009206:Myocardium / Q000378:metabolism; D010306:Parotid Gland / Q000378:metabolism; D011487:Protein Conformation; D011812:Quinuclidines / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology*; D011976:Receptors, Muscarinic / Q000737:chemistry / Q000378:metabolism*; D013329:Structure-Activity Relationship; D001743:Urinary Bladder / Q000378:metabolism
chemical_list: D018727:Muscarinic Antagonists; D011812:Quinuclidines; D011976:Receptors, Muscarinic