title: Disappearance of motor tics after Wernicke's encephalopathy in a patient with Tourette's syndrome.
abstract: Tourette's syndrome (TS) is a disease characterized by multiple motor and vocal tics as well as behavioral abnormalities. The anatomic substrates of this syndrome are not defined. We report a 48-year-old man with TS in whom motor tics disappeared after the onset of a midbrain syndrome related to thiamine deficiency (Wernicke's encephalopathy). MRI study showed a lesion in the dorsal area of the midbrain. This case suggests that loops located in the midbrain tegmentum may influence the presence of motor tics in patients with TS.
authors.affiliation: Department of Neurological and Psychiatric Sciences, University of Florence, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Pantoni
authors.forename: L
authors.initials: L
authors.lastname: Poggesi
authors.forename: A
authors.initials: A
authors.lastname: Repice
authors.forename: D
authors.initials: D
authors.lastname: Inzitari
mesh_terms: D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012075:Remission, Spontaneous; D013981:Tic Disorders / Q000150:complications / Q000473:pathology*; D005879:Tourette Syndrome / Q000150:complications* / Q000473:pathology*; D014899:Wernicke Encephalopathy / Q000150:complications* / Q000473:pathology*