Lupus vulgaris in a patient with systemic lupus erythematosus and persistent IgG deficiency.
We present the case of a patient with juvenile onset systemic lupus erythematosus (SLE) who developed a persistent, acquired hypogammaglobulinaemia with IgG deficiency. The hypogammaglobulinaemia was probably a complication of high dose corticosteroid treatment. The serum IgG level remained subnormal despite intravenous immunoglobulin therapy. Lupus vulgaris, which developed on the nasal cartilage in this patient with SLE, is not an expected finding. This patient is probably the first reported case of SLE associated with lupus vulgaris.
Düzgün
N
N
Department of Immunology, Faculty of Medicine, Ankara University, Turkey.
Duman
M
M
Sonel
B
B
Peksari
Y
Y
Erdem
C
C
Tokgöz
G
G
D000328:Adult; D000361:Agammaglobulinemia / Q000097:blood / Q000139:chemically induced / Q000150:complications; D000995:Antitubercular Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000009:adverse effects; D006801:Humans; D017099:IgG Deficiency / Q000150:complications* / Q000473:pathology / Q000628:therapy; D007136:Immunoglobulins / Q000097:blood; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000473:pathology / Q000628:therapy; D008177:Lupus Vulgaris / Q000150:complications* / Q000473:pathology / Q000628:therapy; D008775:Methylprednisolone / Q000009:adverse effects; D009295:Nasal Bone
D000995:Antitubercular Agents; D005938:Glucocorticoids; D007136:Immunoglobulins; D016756:Immunoglobulins, Intravenous; D008775:Methylprednisolone