Lipopolysaccharide affinity for titanium implant biomaterials.
BACKGROUND
Lipopolysaccharide (LPS) affinity for titanium implant biomaterials could affect crevicular LPS concentrations and thereby influence periimplant inflammation.


OBJECTIVE
The purpose of this study was to evaluate Porphyromonas gingivalis and Escherichia coli LPS affinity for titanium biomaterials groups that differed in surface oxide composition and surface roughness.


METHODS
Polished and abraded grade 1 commercially pure titanium and grade 5 alloyed extra low interstitial titanium specimens were treated with 10 EU/mm2 and radiolabeled LPS.


RESULTS
The resultant mean +/- SD LPS adherence values ranged from 4.17 +/- 0.29 to 4.79 +/- 0.40 EU/ mm2. No difference in adherence and elution was indicated on the basis of LPS type, surface oxide composition, or surface roughness. Moreover, P. gingivalis and F. coli LPS desorption was below detection.


CONCLUSIONS
Clinically, the high affinity of both LPS types for titanium biomaterials may adversely influence the periimplant tissue response.
Nelson
S K
SK
Department of Oral Rehabilitation, Medical College of Georgia, School of Dentistry, Augusta, USA.
Knoernschild
K L
KL
Robinson
F G
FG
Schuster
G S
GS
D000327:Adsorption; D000704:Analysis of Variance; D001422:Bacterial Adhesion; D015921:Dental Implants / Q000009:adverse effects / Q000382:microbiology*; D004866:Equipment Contamination; D004926:Escherichia coli / Q000737:chemistry; D005883:Gingival Crevicular Fluid / Q000382:microbiology; D006244:Hardness; D008070:Lipopolysaccharides / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry; D010518:Periodontitis / Q000209:etiology; D016966:Porphyromonas gingivalis / Q000737:chemistry; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
D015921:Dental Implants; D008070:Lipopolysaccharides; D010087:Oxides; D014025:Titanium