title: [Treatment of drug-induced agranulocytosis with granulocyte colony stimulating factor (G-CSF) in a surgical intensive care unit].
abstract: Following repeated metamizole applications a 41-year old intensive-care patient suffering from severe craniocerebral trauma and sepsis developed a drug-induced agranulocytosis. Early G-CSF treatment reduced the neutropenic period to 4 days.
authors.affiliation: Institut für Anästhesiologie und Operative Intensivmedizin, Klinikum Darmstadt, Johann-Wolfgang-Goethe-Universität Frankfurt/Main.
authors.forename: B
authors.initials: B
authors.lastname: Huss
authors.forename: S
authors.initials: S
authors.lastname: Bogosyan
authors.forename: E
authors.initials: E
authors.lastname: Müller
authors.forename: E
authors.initials: E
authors.lastname: Götz
mesh_terms: D000328:Adult; D000380:Agranulocytosis / Q000139:chemically induced* / Q000628:therapy; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use; D003422:Critical Care; D004177:Dipyrone / Q000009:adverse effects* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage*; D016489:Head Injuries, Closed / Q000628:therapy*; D006801:Humans; D008297:Male
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D016179:Granulocyte Colony-Stimulating Factor; D004177:Dipyrone