Is there psychopathology in the coparents of schizophrenic adoptees' half-siblings?
An excess of schizophrenia has been observed in the biological relatives of adoptees with schizophrenia. The present analysis examined the possibility that illness observed among 90 half-siblings may have been influenced by assortative mating resulting in excess illness in the biological parents of the half-siblings not biologically related to the adoptees (the coparents). We found no difference in the prevalence of mental illness between 44 index and 26 control coparents.
Ingraham
L J
LJ
Laboratory of Psychology and Psychopathology, NIMH, Bethesda, Maryland 20892-1366, USA.
Chan
T F
TF
D000300:Adoption / Q000523:psychology*; D000328:Adult; D016241:Child of Impaired Parents / Q000523:psychology*; D003718:Denmark; D005260:Female; D006801:Humans; D008297:Male; D008957:Models, Genetic; D010641:Phenotype; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis / Q000235:genetics*; D012569:Schizotypal Personality Disorder / Q000175:diagnosis / Q000235:genetics / Q000523:psychology; D012801:Sibling Relations; D012931:Social Environment