[Morphological changes in the vestibular analyzer in the dynamics of an experimental disorder of the cerebral circulation].
The alterations of microcirculatory structures and of neurons as a result of chronic cerebrovascular disturbances induced by ligation of the left common carotid artery were studied on 56 noninbred white male rats. The objects of investigation were central links of vestibular analyser such as anterior vestibular nucleus, posterior ventro-lateral part of hypothalamus, sensomotor brain cortex. It was established that one-sided ligation of common carotid artery resulted in alterations in vessels of microcirculatory bed, in neurons' bodies, in synapses. These disorders were similar to oxygen-deficient damages, described in literature which confirm the model's adequacy. These alterations appeared in different time and had various degree of expression in different structures. The latter observation may reflect different phylogenetic age of the structures studied. The reaction of the neuronal population as the functional system was observed as the process of alterations of the correlation of neurons with different functional activity. This process had periodic pattern.
Nasibullin
B A
BA
Brovina
N N
NN
D000818:Animals; D002561:Cerebrovascular Disorders / Q000473:pathology*; D002908:Chronic Disease; D004195:Disease Models, Animal; D008297:Male; D008854:Microscopy, Electron; D009044:Motor Cortex / Q000473:pathology; D009430:Neural Analyzers / Q000473:pathology*; D009474:Neurons / Q000648:ultrastructure; D051381:Rats; D013787:Thalamic Nuclei / Q000473:pathology; D013997:Time Factors; D014726:Vestibular Nuclei / Q000473:pathology; D014722:Vestibule, Labyrinth / Q000294:innervation / Q000473:pathology*