Neurochemical changes in cerebellum of goldfish exposed to various temperatures.
Acclimation of goldfish at 35 degrees C increased the cerebellar content of aspartate, glutamate, and taurine and [3H]glutamate uptake. Acclimation at 4 degrees C increased the levels of glutamine, serine, and alanine and glutamine synthetase (GS) activity. Adenosine content increased in cerebellum of fish acclimated to warm temperature. K+-evoked release of endogenous and exogenous glutamate from cerebellar slices increased in fish acclimated at 35 degrees C compared to 4 degrees C. The basal level of cyclic adenosine 3':5'-monophosphate (cAMP) in perfused cerebellar slices in fish acclimated at 35 degrees C was much higher than in fish acclimated at 5 degrees and 22 degrees C. It is concluded that variations of environmental temperature produces large neurochemical changes in goldfish cerebellum.
Poli
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A
Department of Biology, University of Bologna, Italy.
Notari
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S
Virgili
M
M
Fabbri
E
E
Lucchi
R
R
D000064:Acclimatization; D000227:Adenine Nucleotides / Q000378:metabolism; D000241:Adenosine / Q000378:metabolism; D000409:Alanine / Q000378:metabolism; D000818:Animals; D001224:Aspartic Acid / Q000378:metabolism; D002531:Cerebellum / Q000187:drug effects / Q000378:metabolism*; D005974:Glutamate-Ammonia Ligase / Q000378:metabolism; D018698:Glutamic Acid / Q000378:metabolism; D005973:Glutamine / Q000378:metabolism; D006054:Goldfish / Q000378:metabolism*; D007700:Kinetics; D011188:Potassium / Q000494:pharmacology; D012694:Serine / Q000378:metabolism; D013654:Taurine / Q000378:metabolism; D013696:Temperature
D000227:Adenine Nucleotides; D005973:Glutamine; D013654:Taurine; D001224:Aspartic Acid; D018698:Glutamic Acid; D012694:Serine; D005974:Glutamate-Ammonia Ligase; D000241:Adenosine; D000409:Alanine; D011188:Potassium