title: Chronologic change of serum IgG antibody response in chickens reinfected with Cryptosporidium baileyi.
abstract: Eight 2-day-old SPF chickens were each inoculated orally with a single dose of 5 x 10(5) oocysts of Cryptosporidium baileyi, and immunoglobulin G (IgG) antibody responses were chronologically measured by indirect immunofluorescent antibody (IFA) assay. Anti-C. baileyi IgG antibody levels remained high (1:106.67 to 1:512.00) for at least 4 months with 330 days of a detectable period. Ten days after the negative conversion, each chicken was re-challenged with 1 x 10(7) oocysts of the same species. Subsequent infection in 340-day-old individuals caused sudden elevated IgG antibody levels and the titer peaked on day 28 postchallenge inoculation (PCI), at 1:1.024 with a 65 days of detection period. Chickens in primary infection showed oocyst shedding profiles, but did not exhibit any oocyst shedding before or after experimental reinfection.
authors.affiliation: Bio-Safety Research Institute, Chonbuk National University, Chonju, Korea.
authors.forename: J K
authors.initials: JK
authors.lastname: Rhee
authors.forename: H C
authors.initials: HC
authors.lastname: Kim
authors.forename: B K
authors.initials: BK
authors.lastname: Park
mesh_terms: D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D002645:Chickens; D003457:Cryptosporidiosis / Q000276:immunology*; D003458:Cryptosporidium / Q000276:immunology*; D019084:Fluorescent Antibody Technique, Indirect; D007074:Immunoglobulin G / Q000097:blood*; D015166:Monitoring, Immunologic; D013997:Time Factors
chemical_list: D000913:Antibodies, Protozoan; D007074:Immunoglobulin G