title: Intravenous clofilium for conversion of atrial fibrillation.
abstract: Clofilium was administered to 14 patients with mainly chronic atrial fibrillation in a pilot study. QTc prolongation was observed, and 2 patients had conversion to sinus rhythm after drug infusion.
authors.affiliation: Cardiovascular Division, Henry Ford Hospital, Detroit, Michigan 48202, USA.
authors.forename: S
authors.initials: S
authors.lastname: Borzak
authors.forename: N
authors.initials: N
authors.lastname: Al-Khaled
authors.forename: L
authors.initials: L
authors.lastname: Douthat
authors.forename: M
authors.initials: M
authors.lastname: Steinberg
authors.forename: A D
authors.initials: AD
authors.lastname: Goldberg
mesh_terms: D000328:Adult; D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000188:drug therapy* / Q000503:physiopathology; D002908:Chronic Disease; D005260:Female; D006329:Heart Conduction System / Q000187:drug effects; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D000644:Quaternary Ammonium Compounds / Q000494:pharmacology / Q000627:therapeutic use*
chemical_list: D000889:Anti-Arrhythmia Agents; D000644:Quaternary Ammonium Compounds; C022799:clofilium