title: [New approaches to determining the type classification of presynaptic acetylcholine receptors].
abstract: A complex of special tests which took into account the coupling of the specific physiological responses with individual subtypes of muscarinic cholinoceptors, and radioligand analysis showed the predominance of M3- and M2-subtype presynaptic receptors in the rat brain hemispheres. The autoreceptors regulating the presynaptic release of acetylcholine are related mainly to the M2-subtype and account for the smaller part of the mixed population of presynaptic receptors.
authors.forename: A B
authors.initials: AB
authors.lastname: Kosmachev
authors.forename: V N
authors.initials: VN
authors.lastname: Filippov
authors.forename: N P
authors.initials: NP
authors.lastname: Podosinovikova
authors.forename: L F
authors.initials: LF
authors.lastname: Gorobets
authors.forename: V B
authors.initials: VB
authors.lastname: Dolgo-Saburov
authors.forename: N M
authors.initials: NM
authors.lastname: Libman
authors.forename: N E
authors.initials: NE
authors.lastname: Solov'eva
mesh_terms: D000818:Animals; D001115:Arecoline / Q000494:pharmacology; D001921:Brain / Q000187:drug effects / Q000502:physiology; D018680:Cholinergic Antagonists / Q000494:pharmacology; D004006:Dichlorvos / Q000633:toxicity; D004347:Drug Interactions; D005260:Female; D008297:Male; D018721:Muscarinic Agonists / Q000494:pharmacology; D010862:Pilocarpine / Q000494:pharmacology; D011869:Radioligand Assay; D051381:Rats; D011950:Receptors, Cholinergic / Q000145:classification* / Q000187:drug effects / Q000502:physiology; D017661:Receptors, Presynaptic / Q000037:antagonists & inhibitors / Q000145:classification* / Q000187:drug effects / Q000502:physiology; D012472:Salivation / Q000187:drug effects; D014202:Tremor / Q000139:chemically induced
chemical_list: D018680:Cholinergic Antagonists; D018721:Muscarinic Agonists; D011950:Receptors, Cholinergic; D017661:Receptors, Presynaptic; D010862:Pilocarpine; D001115:Arecoline; D004006:Dichlorvos