Squamometry in rating the efficacy of topical corticosteroids in atopic dermatitis.
OBJECTIVE
Squamometry is a non-invasive test allowing a reproducible rating of cutaneous xerosis including atopic dermatitis lesions. The method was used to compare the efficacy of proprietary topical corticosteroids in alleviating signs of atopic xerosis.


RESULTS
The steroid compounds and their vehicles improve the texture of the stratum corneum at different rates after treatment for 1 week. Some differences in efficacy may be explained by the nature of the vehicle, which enhances the basic pharmacological activity of the corticosteroid itself.
Letawe
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Department of Dermatopathology, University of Liège, Belgium.
Piérard-Franchimont
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Piérard
G E
GE
D000287:Administration, Topical; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003876:Dermatitis, Atopic / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012867:Skin / Q000473:pathology
D000305:Adrenal Cortex Hormones