title: Validated high-performance liquid chromatographic method for quantitation of neohesperidine dihydrochalcone in foodstuffs.
abstract: An analytical method to detect and quantitate neohesperidine dihydrochalcone in foodstuffs has been developed and validated in soft-drink applications. The method was shown to be sufficiently precise, accurate, selective and rugged in quantitating neohesperidine DC both at flavouring (1-5 mg/kg) and sweetening (5-50 mg/kg) levels. Applications of the method to determine neohesperidine DC in foodstuffs other than soft-drinks is also described.
authors.affiliation: Zoster, S.A. (Grupo Ferrer), Zeneta (Murcia), Spain.
authors.forename: H
authors.initials: H
authors.lastname: Montijano
authors.forename: F
authors.initials: F
authors.lastname: Borrego
authors.forename: I
authors.initials: I
authors.lastname: Canales
authors.forename: F A
authors.initials: FA
authors.lastname: Tomás-Barberán
mesh_terms: D002182:Candy / Q000032:analysis; D002253:Carbonated Beverages / Q000032:analysis; D002599:Chalcone / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry; D047188:Chalcones; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D005503:Food Additives / Q000032:analysis* / Q000737:chemistry; D005504:Food Analysis; D006569:Hesperidin / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry; D008383:Margarine / Q000032:analysis; D009994:Osmolar Concentration; D015203:Reproducibility of Results; D012997:Solvents / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet; D013549:Sweetening Agents / Q000032:analysis* / Q000737:chemistry; D015014:Yogurt / Q000032:analysis
chemical_list: D047188:Chalcones; D005503:Food Additives; D012997:Solvents; D013549:Sweetening Agents; C013613:neohesperidin dihydrochalcone; D002599:Chalcone; D008383:Margarine; D006569:Hesperidin