Genetic polymorphisms of orosomucoid ORM1 and ORM2 in Egyptians, Sudanese, and Qataris: occurrence of two new alleles.
Isoelectric focusing was used to investigate the genetic variants of the human plasma orosomucoid ORM1 and ORM2 gene loci in samples of Egyptians, Sudanese, and Qataris. The study populations were classified into 28 ORM phenotypes determined by 10 ORM1 and 9 ORM2 alleles that included 2 new alleles, designated ORM1*B13 and ORM2*H21. Family studies of these new alleles are in accordance with codominant autosomal inheritance. A new interpretation for two previously reported alleles, ORM1*C6 and ORM2*H17, is also presented.
Sebetan
I M
IM
Department of Legal Medicine, Nihon University School of Medicine, Tokyo, Japan.
Oshida
S
S
Yuasa
I
I
Tie
J
J
D000483:Alleles; D004534:Egypt; D005787:Gene Frequency; D006801:Humans; D009961:Orosomucoid / Q000235:genetics*; D010641:Phenotype; D011110:Polymorphism, Genetic; D011780:Qatar; D013397:Sudan
D009961:Orosomucoid