title: Estimation of thyroid gland volume by spiral computed tomography.
abstract: The objective of this study was to test the accuracy of CT for the estimation of the volume of enlarged thyroid glands. An unenhanced spiral CT scan of neck and upper mediastinum was obtained in 36 patients with an enlarged thyroid gland. By manual segmentation the surface of the thyroid gland on 5-mm-thick slices was calculated; these surfaces were multiplied by the slice interval (10 mm) and summated to obtain the volume of the gland. All patients underwent a total or subtotal thyroidectomy. 1 cm3 of thyroid gland tissue was considered to weigh 1 g. A good correlation was found between the volume estimated by CT and the weight at pathological examination of the resected gland (r = 0.98, p < 0.001), with a mean difference of + 12 % (range: + 57.3 to -13.9 %). The volume calculation is reproducible among different observers (r = 0.99, p < 0.01). Computed tomography allows an easy, reliable and reproducible volume determination of enlarged thyroid glands.
authors.affiliation: Department of Radiology, University Hospitals, Catholic University of Leuven, Herestraat 49, B-3000 Leuven, Belgium.
authors.forename: R
authors.initials: R
authors.lastname: Hermans
authors.forename: R
authors.initials: R
authors.lastname: Bouillon
authors.forename: K
authors.initials: K
authors.lastname: Laga
authors.forename: P R
authors.initials: PR
authors.lastname: Delaere
authors.forename: B D
authors.initials: BD
authors.lastname: Foer
authors.forename: G
authors.initials: G
authors.lastname: Marchal
authors.forename: A L
authors.initials: AL
authors.lastname: Baert
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013959:Thyroid Diseases / Q000000981:diagnostic imaging / Q000601:surgery; D013961:Thyroid Gland / Q000000981:diagnostic imaging* / Q000473:pathology; D013965:Thyroidectomy; D014057:Tomography, X-Ray Computed / Q000379:methods*