title: [Clinicopathological study of pulmonary hamartoma with special reference to 6 patients who also had another tumor].
abstract: We studied 22 patients in whom intrapulmonary hamartoma was diagnosed between 1975 and 1994. Twelve were men and 10 were women, and their ages ranged from 20 to 72 years (averaged: 52.5). The sizes of the hamartomas ranged from 5 mm to 3 cm. Five patients also had other types of cancer (ling 3, colon 1, thyroid 1) and one had a mediastinal tumor (1). In those 6 patients, the hamartomas had to be distinguished from intrapulmonary metastasis. In 2 of those 6, thoracoscopic surgery was useful for obtaining sufficient materials for diagnosis. In one patient immunohistochemical analysis with anti-PCNA (proliferative cell nuclear antigen) antibody was useful in distinguishing leiomyomatous hamartoma from benign metastatic leiomyoma.
authors.affiliation: Department of Pathology, Tokai University School of Medicine, Kanagawa, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Abe
authors.forename: S
authors.initials: S
authors.lastname: Shioya
authors.forename: Y
authors.initials: Y
authors.lastname: Ohshika
authors.forename: E
authors.initials: E
authors.lastname: Ota
authors.forename: M
authors.initials: M
authors.lastname: Iwasaki
authors.forename: H
authors.initials: H
authors.lastname: Inoue
authors.forename: M
authors.initials: M
authors.lastname: Nakamura
authors.forename: T
authors.initials: T
authors.lastname: Ogata
authors.forename: N
authors.initials: N
authors.lastname: Tamaoki
mesh_terms: D000328:Adult; D000368:Aged; D003110:Colonic Neoplasms / Q000150:complications; D003937:Diagnosis, Differential; D005260:Female; D006222:Hamartoma / Q000150:complications / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008171:Lung Diseases / Q000150:complications / Q000473:pathology*; D008175:Lung Neoplasms / Q000150:complications; D008297:Male; D008875:Middle Aged; D018809:Proliferating Cell Nuclear Antigen / Q000032:analysis; D013964:Thyroid Neoplasms / Q000150:complications
chemical_list: D018809:Proliferating Cell Nuclear Antigen