title: [Experience with using high doses of cerebrolysin in vascular dementia].
abstract: The efficacy and tolerability of high-dose neurotrophic drug cerebrolysin was studied in 20 patients with vascular dementia diagnosed by criteria NINDS-AIREN and DSM-IV. The drug was well tolerated, affected positively cognitive function, especially neurodynamic processes. EEG featured after treatment intensification of rapid rhythms power and a decrease in delta-activity spectrum. The highest effect of cerebrolysin was achieved in patients with mild cognitive defects.
authors.forename: N N
authors.initials: NN
authors.lastname: Iakhno
authors.forename: I V
authors.initials: IV
authors.lastname: Damulin
authors.forename: V V
authors.initials: VV
authors.lastname: Zakharov
authors.forename: O S
authors.initials: OS
authors.lastname: Levin
authors.forename: M N
authors.initials: MN
authors.lastname: Elkin
mesh_terms: D000368:Aged; D000596:Amino Acids / Q000008:administration & dosage*; D002908:Chronic Disease; D015140:Dementia, Vascular / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D004341:Drug Evaluation; D004569:Electroencephalography / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination / Q000187:drug effects; D009484:Neuropsychology; D018697:Nootropic Agents / Q000008:administration & dosage*
chemical_list: D000596:Amino Acids; D018697:Nootropic Agents; C006952:cerebrolysin