[The stimulating action of exogenous RNase on eubiotic strains of Lactobacillus, Bifidobacterium and Escherichia coli].
The influence of Bacillus intermedius RNAase on the multiplication on B.B.bifidum, L.fermentum and E. coli was studied. The study revealed that the stimulating action depended on the dose of the enzyme, the microbial species and the growth phase of the inoculate. RNAase, added to the nutrient medium, was shown to induce the acceleration of the synthesis of DNA, RNA, protein, as well as mitosis. At the same time the stimulating action of RNAase was accompanied not only by the reduction of the duration of the lag phase, but in some cases even by an increase in the specific growth rate.
Kolpakov
A I
AI
Bondarenko
V M
VM
Kupriianova-Ashina
F G
FG
Egorov
S Iu
SIu
D001407:Bacillus / Q000201:enzymology; D001426:Bacterial Proteins / Q000096:biosynthesis / Q000187:drug effects; D001644:Bifidobacterium / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D002455:Cell Division / Q000187:drug effects; D003470:Culture Media; D004269:DNA, Bacterial / Q000096:biosynthesis / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004553:Electric Conductivity; D004926:Escherichia coli / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D007778:Lactobacillus / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D012329:RNA, Bacterial / Q000096:biosynthesis / Q000187:drug effects; D012260:Ribonucleases / Q000494:pharmacology*; D013268:Stimulation, Chemical
D001426:Bacterial Proteins; D003470:Culture Media; D004269:DNA, Bacterial; D012329:RNA, Bacterial; D012260:Ribonucleases