title: Neoagarobiose as a novel moisturizer with whitening effect.
abstract: Neoagarobiose, a disaccharide, showed a higher hygroscopic ability than glycerol or hyaluronic acid, typical moisturizing reagents. Beside, neoagarobiose whitened B16 murine melanoma cells, and showed low cytotoxicity. Therefore neoagarobiose was a rare reagent showing both moisturizing and whitening effects.
authors.affiliation: KOSE Corporation, Basic Research Laboratory, Tokyo, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Kobayashi
authors.forename: M
authors.initials: M
authors.lastname: Takisada
authors.forename: T
authors.initials: T
authors.lastname: Suzuki
authors.forename: K
authors.initials: K
authors.lastname: Kirimura
authors.forename: S
authors.initials: S
authors.lastname: Usami
mesh_terms: D000818:Animals; D001104:Arbutin / Q000494:pharmacology; D004187:Disaccharides / Q000737:chemistry* / Q000494:pharmacology*; D008545:Melanoma / Q000188:drug therapy / Q000473:pathology; D051379:Mice; D011753:Pyrones / Q000494:pharmacology; D017592:Skin Care / Q000379:methods; D014407:Tumor Cells, Cultured; D017155:Wettability
chemical_list: D004187:Disaccharides; D011753:Pyrones; C068544:neoagarobiose; C011890:kojic acid; D001104:Arbutin