title: [Effect of automatically titrated CPAP systems on sleep and respiration in sleep apnea syndrome].
abstract: We compared an automated self setting CPAP-titration with conventional constant CPAP. In 12 patients with obstructive sleep apnea syndrome 2 polysomnographies were performed after introduction of CPAP-therapy. In a randomized cross-over study a constant CPAP during one night and in a second night a computerized variation of pressure was applied by a self-setting CPAP-device (Auto AdjustTM CPAP). During both methods apneas, hypopneas and snoring were reduced. Apnea index was reduced from 32.5 +/- 28.5 at diagnosis to 3.3 +/- 4.7 by Auto Adjust CPAP and to 4.0 +/- 5.3 by constant CPAP. The results of the 2 methods were not significantly different. Total sleep-time, sleep efficiency and sleep stages did not show any significant difference.
  
  
  CONCLUSIONS
  In case of pressure-intolerance automated self setting CPAP offers an alternative beneath BiPAP. The significance of this method with regard to BiPAP therapy must further be evaluated.
authors.affiliation: Klinik Ambrock, Klinik für Pneumologie, Hagen, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Hoster
authors.forename: E
authors.initials: E
authors.lastname: Schlenker
authors.forename: K H
authors.initials: KH
authors.lastname: Rühle
mesh_terms: D000403:Airway Resistance / Q000502:physiology; D001143:Arousal / Q000502:physiology; D018592:Cross-Over Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography / Q000295:instrumentation*; D011175:Positive-Pressure Respiration / Q000295:instrumentation*; D012123:Pulmonary Ventilation / Q000502:physiology; D012891:Sleep Apnea Syndromes / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D012894:Sleep Stages / Q000502:physiology*; D013813:Therapy, Computer-Assisted / Q000295:instrumentation*; D016896:Treatment Outcome