title: Direct invasion of the renal vein by metastatic testicular cancer.
abstract: We report a case of metastatic seminoma with direct invasion of the left renal vein. A tumor thrombus was found in the renal vein while the vena cava thrombosis proved to be a noncancerous blood clot developing as an extension of the tumor thrombus. Primary chemotherapy could not be completed because of thrombotic growth requiring surgical intervention. Although surgical specimens were free of viable tumor and two cycles of adjuvant chemotherapy were applied, the tumor relapsed in the area of renal vein invasion.
authors.affiliation: Department of Urology, RWTH University of Aachen, Germany.
authors.forename: P J
authors.initials: PJ
authors.lastname: Effert
authors.forename: G
authors.initials: G
authors.lastname: Wendt
authors.forename: S
authors.initials: S
authors.lastname: Handt
authors.forename: J M
authors.initials: JM
authors.lastname: Wolff
authors.forename: R
authors.initials: R
authors.lastname: Keulers
authors.forename: G
authors.initials: G
authors.lastname: Jakse
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D009361:Neoplasm Invasiveness; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D012082:Renal Veins / Q000473:pathology*; D018239:Seminoma / Q000150:complications / Q000473:pathology* / Q000628:therapy; D013736:Testicular Neoplasms / Q000150:complications / Q000473:pathology* / Q000628:therapy; D013927:Thrombosis / Q000150:complications / Q000473:pathology; D014682:Vena Cava, Inferior