[On the reversal of schistosomiasis hepatic fibrosis after specific therapy. Histopathologic study].
Surgical liver biopsies of patients of both sexes, between 18 and 72 years old, with the compensated hepatoesplenic form of schistosomiasis mansoni, previously treated with oxaminique (Mansil) were studied by histological and immunohistochemical methods. Although the search for parasites and/or granulomas was negative in all specimen studied, the portal fibrosis remained.
Chapadeiro
E
E
Departamento de Patologia, Medicina Legal e do Curso de Pós-graduação em Patologia Humana da Faculdade de Medicina do Triângulo Mineiro, Uberaba, MG, Brasil.
Pitanga
L C
LC
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D005260:Female; D006801:Humans; D008103:Liver Cirrhosis / Q000188:drug therapy* / Q000473:pathology*; D008109:Liver Diseases, Parasitic / Q000188:drug therapy* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010073:Oxamniquine / Q000627:therapeutic use*; D012550:Schistosoma mansoni; D012555:Schistosomiasis mansoni / Q000188:drug therapy* / Q000473:pathology*; D012556:Schistosomicides / Q000627:therapeutic use*
D012556:Schistosomicides; D010073:Oxamniquine