title: Uptake of 99mTc-MDP after uncemented hip arthroplasty: a quantitative analysis of findings around the femoral component in asymptomatic patients.
abstract: We studied the pattern of 99mTc-methylene diphosphonate uptake around uncemented femoral components in 44 asymptomatic hip arthroplasties, performing isotope scans at intervals from 4 to 48 months after operation. We used phase-II images obtained with a high-resolution gamma camera and measured the activity in various zones using a specially designed computer program. The components studied at 4, 6, 9 and 12 months were coated with hydroxyapatite (HA) and those studied at 18, 24, 36 and 48 months were not coated. We found a statistically significant fall in activity between four and six months around HA-coated prostheses in all five femoral periprosthetic zones. After six months activity was relatively uniform, but remained higher than that in normal femoral bone at 48 months in non-coated prostheses. We discuss the application of these patterns in the evaluation of painful cementless hip arthroplasties.
authors.affiliation: Colchester General Hospital and Black Notley Regional Orthopaedic Centre, Braintree, England.
authors.forename: R N
authors.initials: RN
authors.lastname: Maniar
authors.forename: R C
authors.initials: RC
authors.lastname: Todd
authors.forename: S
authors.initials: S
authors.lastname: Robinson
authors.forename: M
authors.initials: M
authors.lastname: Critchley
mesh_terms: D000328:Adult; D005260:Female; D005269:Femur / Q000378:metabolism*; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000601:surgery; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate
chemical_list: D013669:Technetium Tc 99m Medronate