title: Genome rearrangements of rotaviruses.
abstract: Rotaviruses (and other members of the Reoviridae family) undergo rearrangements of their genomes. This review describes evidence of rearranged genomes in rotaviruses. Their structure and functions are reviewed. Possible mechanisms of their emergence are discussed, and the significance of genome rearrangements for viral evolution is considered.
authors.affiliation: Clinical Microbiology and Public Health Laboratory, Addenbrooke's Hospital, Cambridge, UK.
authors.forename: U
authors.initials: U
authors.lastname: Desselberger
mesh_terms: D000818:Animals; D001483:Base Sequence; D019143:Evolution, Molecular; D015321:Gene Rearrangement; D016679:Genome, Viral; D006801:Humans; D008969:Molecular Sequence Data; D012367:RNA, Viral / Q000032:analysis*; D012087:Reoviridae / Q000235:genetics; D012401:Rotavirus / Q000235:genetics*
chemical_list: D012367:RNA, Viral