Erosive pustular dermatosis of the scalp in skin grafts: report of three cases.
Three patients developed erosive pustular dermatosis of the scalp (EPDS). Two of them, both males, had previously undergone surgical excision for squamous cell carcinoma and basal cell carcinoma, and a female experienced avulsive trauma of the scalp. The erosive lesions and crusts were located at the site of a skin graft; microbiological cultures were negative for bacterial and fungal growth. Histological examination ruled out pustular bullous disorders. Topical therapy with corticosteroids and antibiotics resulted in clinical remission in only 2 cases. The third case showed a tendency to recur despite numerous therapeutic attempts with oral dapsone and isotretinoin. We conclude that surgical trauma is a possible cause of EPDS. Our patients seem to be the first reported cases of EPDS in skin grafts following plastic surgical procedures.
Ena
P
P
Department of Dermatology, Faculty of Medicine, Sassari University, Italy.
Lissia
M
M
Doneddu
G M
GM
Campus
G V
GV
D000279:Administration, Cutaneous; D000284:Administration, Oral; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001419:Bacteria / Q000302:isolation & purification; D001623:Betamethasone / Q000008:administration & dosage / Q000627:therapeutic use; D002280:Basal Cell Carcinoma / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D003622:Dapsone / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005658:Fungi / Q000302:isolation & purification; D005839:Gentamicins / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage / Q000627:therapeutic use; D007641:Keratolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012074:Remission Induction; D012535:Scalp / Q000293:injuries / Q000601:surgery; D012536:Scalp Dermatoses / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D012878:Skin Neoplasms / Q000601:surgery; D016038:Skin Transplantation / Q000009:adverse effects*
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D005839:Gentamicins; D007641:Keratolytic Agents; D003622:Dapsone; D001623:Betamethasone; D015474:Isotretinoin