title: [A case of Kikuchi disease. Review of the literature].
abstract: We report a case of Kikuchi's disease in a young man. It is a rare entity, described for the first time in 1972. It manifests clinically with cervical adenopathy and fever, often associated with other non-specific clinical signs. Laboratory tests are often normal. The diagnosis is established on the basis of histologic of lymph node excisional biopsy. Kikuchi's disease is likely to be misinterpreted as malignant lymphoma or systemic lupus erythematosus. It generally needs no treatment because it runs a spontaneously benign course with complete resolution of the symptoms within 6 months. Secondary systemic lupus erythematosus may develop. For this reason, regular follow-up of patients is recommended. The etiopathogenesis of this disease is still unknown, perhaps due to an immunologic phenomenon. It could be a hyperimmune reaction induced by various antigenic agents (infectious, neoplasic), or an autoimmune process.
authors.affiliation: Service ORL, CHU, Caen.
authors.forename: A
authors.initials: A
authors.lastname: Bequignon
authors.forename: S
authors.initials: S
authors.lastname: Moreau
authors.forename: M
authors.initials: M
authors.lastname: Goullet de Rugy
authors.forename: N
authors.initials: N
authors.lastname: Bourdon
authors.forename: E
authors.initials: E
authors.lastname: Babin
authors.forename: A
authors.initials: A
authors.lastname: Valdazo
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis; D008198:Lymph Nodes / Q000473:pathology; D008199:Lymphadenitis / Q000175:diagnosis / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D009336:Necrosis