title: [The differentiation of the surface mucous-cell line in the abomasum of the adult cow].
abstract: The differentiation of the surface mucous-cell lineage during physiological cell renewal was investigated using light and electron microscopy in the abomasal mucosa of adult cattle. The surface mucous cells constitute a morphologically and functionally heterogeneous population, whose members correspond to different developmental stages, OFFanged in a distoproximal gradient from the depth of the pit towards the free luminal surface. The cell lineage comprises immature pre-pit cells near the proliferative isthmus, mature pit cells within the foveola, and older interfoveolar cells lining the free surface. Ultrastructurally, differentiation can be traced towards a predominantly mucus-producing cell type and finally towards a surface-protective cell variant, which degenerates in situ and is extruded into the lumen without affecting epithelial integrity.
authors.affiliation: Institut für Veterinär-Anatomie, -Histologie und -Embryologie der Justus-Liebig-Universität Giessen, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Kressin
authors.forename: U
authors.initials: U
authors.lastname: Sommer
mesh_terms: D000018:Abomasum / Q000166:cytology* / Q000502:physiology / Q000648:ultrastructure; D000818:Animals; D002417:Cattle; D002454:Cell Differentiation / Q000502:physiology; D005260:Female; D005753:Gastric Mucosa / Q000166:cytology* / Q000502:physiology / Q000648:ultrastructure; D008854:Microscopy, Electron