Ultrastructural basis for gene expression at the synapse: synapse-associated polyribosome complexes.
This review summarizes what is known about the protein synthetic machinery that is selectively localized beneath postsynaptic sites on the dendrites of CNS neurons. This machinery, made up of polyribosomes and associated membranous cisterns, allows a local synthesis of key proteins at individual postsynaptic sites.
Steward
O
O
Department of Neuroscience, University of Virginia Health Sciences Center, Charlottesville 22908, USA.
Falk
P M
PM
Torre
E R
ER
D000818:Animals; D002490:Central Nervous System / Q000502:physiology* / Q000648:ultrastructure; D003712:Dendrites / Q000502:physiology / Q000648:ultrastructure; D015870:Gene Expression; D008961:Models, Structural; D009419:Nerve Tissue Proteins / Q000096:biosynthesis*; D009474:Neurons / Q000502:physiology* / Q000648:ultrastructure; D015388:Organelles / Q000502:physiology / Q000648:ultrastructure; D011132:Polyribosomes / Q000502:physiology* / Q000648:ultrastructure*; D013569:Synapses / Q000502:physiology* / Q000648:ultrastructure*
D009419:Nerve Tissue Proteins