title: Pre-operative oral administration of morphine in day-case gynaecological laparoscopy.
abstract: The analgesic effect of morphine sulphate 10 mg by mouth given pre-operatively on pain after gynaecological laparoscopy was studied in a randomised, prospective, double-blind, placebo-controlled comparison. Two groups of 56 patients were studied one group undergoing diagnostic laparoscopy and the other laparoscopic sterilisation. All patients received a standard anaesthetic after premedication with morphine or placebo 1 h before the operation. Morphine premedication did not significantly influence postoperative pain as assessed on a visual analogue scale in either group and postoperative opioid consumption was unaffected. Premedication with morphine 10 mg orally does not significantly decrease pain after day-case gynaecological laparoscopy.
authors.affiliation: Birmingham and Midlands Hospital for Women, Sparkhill.
authors.forename: R
authors.initials: R
authors.lastname: Rasanayagam
authors.forename: G
authors.initials: G
authors.lastname: Harrison
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000556:Ambulatory Surgical Procedures; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D004311:Double-Blind Method; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage*; D010149:Postoperative Pain / Q000517:prevention & control; D011229:Preanesthetic Medication; D011446:Prospective Studies; D013246:Sterilization, Tubal
chemical_list: D000701:Analgesics, Opioid; D009020:Morphine