title: [Sedation with oral hydroxyzine and rectal chloral hydrate in pediatric MRI and CT].
abstract: OBJECTIVE
  To assess the efficacy and risks of oral hydroxyzine and rectal chloral hydrate to sedate children undergoing CT or MRI.
  
  
  METHODS
  110 children underwent 117 studies. Medical history, treatments, doses per kg of sedative drugs, study quality, sedation time and side effects were prospectively recorded.
  
  
  RESULTS
  25 minutes was the mean time necessary to put children to sleep, 59 minutes was the mean time of sedation 96% of studies were interpretable. 2 children showed transient side effects.
  
  
  CONCLUSIONS
  This sedation regimen appeared efficient. However, its limitations and risks have to be known by radiologists. Sedation-related problems also have to be considered by hospital managers when a new CT or MR equipment is being acquired.
authors.affiliation: Radiopédiatrié, CHU Rouen, Hôpital Charles-Nicolle.
authors.forename: J N
authors.initials: JN
authors.lastname: Dacher
authors.forename: S
authors.initials: S
authors.lastname: Neuenschwander
authors.forename: M
authors.initials: M
authors.lastname: Monroc
authors.forename: A
authors.initials: A
authors.lastname: Vanier
authors.forename: D
authors.initials: D
authors.lastname: Eurin
authors.forename: P
authors.initials: P
authors.lastname: Le Dosseur
mesh_terms: D000284:Administration, Oral; D000285:Administration, Rectal; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D002697:Chloral Hydrate / Q000008:administration & dosage* / Q000009:adverse effects; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006919:Hydroxyzine / Q000008:administration & dosage* / Q000009:adverse effects; D006993:Hypnotics and Sedatives / Q000008:administration & dosage* / Q000009:adverse effects; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D006993:Hypnotics and Sedatives; D006919:Hydroxyzine; D002697:Chloral Hydrate