[Ionizing radiation and bladder cancer].
A retrospective analysis of 160 cases of bladder tumors in females revealed that in 9 of these cases cancer in the bladder arose 1 to 22 years after radiation for uterine and breast cancer. This secondary tumor manifested in 2 females as dysuria, in one of them transition cell cancer of the bladder followed Brunno's cystitis 2 years after the cystitis diagnosis. The other patients had macrohematuria. Being a frequent complication of radiotherapy of pelvic cancer, dysuria and macrohematuria should not be considered as a sign of radiation-induced cystitis. Such patients should be carefully followed up with annual microscopic and cytological examinations of residual urine and cystoscopic control.
Prianichnikova
M B
MB
D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000209:etiology*; D016609:Neoplasms, Second Primary / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects; D012189:Retrospective Studies; D013997:Time Factors; D001749:Urinary Bladder Neoplasms / Q000209:etiology*