title: The interleukin-1 beta converting enzyme family of cysteine proteases.
abstract: Interleukin-1 beta converting enzyme (ICE) is the first enzyme of a new family of cysteine endoproteinases to be isolated and characterized. An overview of the structure and activity of ICE is outlined together with highlights of salient features common to members of each of the family members.
authors.affiliation: Department of Inflammation Research, Merck Research Laboratories 07065, USA.
authors.forename: D K
authors.initials: DK
authors.lastname: Miller
authors.forename: J
authors.initials: J
authors.lastname: Myerson
authors.forename: J W
authors.initials: JW
authors.lastname: Becker
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D001665:Binding Sites; D020170:Caspase 1; D003546:Cysteine Endopeptidases / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D008958:Models, Molecular; D008969:Molecular Sequence Data; D010802:Phylogeny; D011487:Protein Conformation; D017386:Sequence Homology, Amino Acid
chemical_list: D003546:Cysteine Endopeptidases; D020170:Caspase 1