title: Cosmid-derived markers anchoring the bovine genetic map to the physical map.
abstract: The mapping strategy for the bovine genome described in this paper uses large insert clones as a tool for physical mapping and as a source of highly polymorphic microsatellites for genetic typing, and was one objective of the BovMap Project funded by the European Union (UE). Eight-three cosmid and phage clones were characterized and used to physically anchor the linkage groups defining all the bovine autosomes and the X Chromosome (Chr). By combining physical and genetic mapping, clones described in this paper have led to the identification of the linkage groups corresponding to Chr 9, 12, 16, and 25. In addition, anchored loci from this study were used to orient the linkage groups corresponding to Chr 3, 7, 8, 9, 13, 16, 18, 19, and 28 as identified in previously published maps. Comparison of the estimated size of the physical and linkage maps suggests that the genetic length of the bovine genome may be around 4000 cM.
authors.affiliation: IDVGA-CNR, Milan, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Ferretti
authors.forename: B G
authors.initials: BG
authors.lastname: Urquhart
authors.forename: A
authors.initials: A
authors.lastname: Eggen
authors.forename: I
authors.initials: I
authors.lastname: Olsaker
authors.forename: B
authors.initials: B
authors.lastname: Harlizius
authors.forename: B
authors.initials: B
authors.lastname: Castiglioni
authors.forename: A
authors.initials: A
authors.lastname: Mezzelani
authors.forename: S
authors.initials: S
authors.lastname: Solinas Toldo
authors.forename: U
authors.initials: U
authors.lastname: Thieven
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: A L
authors.initials: AL
authors.lastname: Morgan
authors.forename: V M
authors.initials: VM
authors.lastname: Teres
authors.forename: M
authors.initials: M
authors.lastname: Schwerin
authors.forename: I
authors.initials: I
authors.lastname: Martin-Burriel
authors.forename: B P
authors.initials: BP
authors.lastname: Chowdhary
authors.forename: G
authors.initials: G
authors.lastname: Erhardt
authors.forename: I J
authors.initials: IJ
authors.lastname: Nijman
authors.forename: E P
authors.initials: EP
authors.lastname: Cribiu
authors.forename: W
authors.initials: W
authors.lastname: Barendse
authors.forename: H
authors.initials: H
authors.lastname: Leveziel
authors.forename: R
authors.initials: R
authors.lastname: Fries
authors.forename: J L
authors.initials: JL
authors.lastname: Williams
mesh_terms: D000818:Animals; D002417:Cattle / Q000235:genetics*; D002871:Chromosome Banding; D002874:Chromosome Mapping; D003360:Cosmids / Q000235:genetics*; D005260:Female; D008040:Genetic Linkage; D008297:Male; D018895:Microsatellite Repeats; D016324:Sequence Tagged Sites