title: Thyroid autonomy with color-coded image-directed Doppler sonography: internal hypervascularization for the recognition of autonomous adenomas.
abstract: In a prospective study, we assessed the possibility of recognizing autonomous adenomas of the thyroid with color-coded image-directed Doppler sonography using internal hypervascularization in thyroid nodules for identification. Fifty-three patients with thyroid nodules underwent additional CCDS examination and nuclear scintigraphy (reference). Of 29 patients having autonomous adenomas, 28 patients presented internal hypervascularization in their nodules resulting in a sensitivity of 96% and a specificity was 75%. Interestingly CCDS detected six adenomas in patients showing normal laboratory data (bTSH, TT3, FT4). CCDS could be used to exclude focal adenomas with a negative predictive value of 94%. The positive predictive value for adenoma was 82%.
authors.affiliation: Department of Medicine I, Friedrich-Alexander-University, Erlangen-Nuremberg, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Becker
authors.forename: H J
authors.initials: HJ
authors.lastname: Bair
authors.forename: W
authors.initials: W
authors.lastname: Becker
authors.forename: E
authors.initials: E
authors.lastname: Günter
authors.forename: W
authors.initials: W
authors.lastname: Lohner
authors.forename: S
authors.initials: S
authors.lastname: Lerch
authors.forename: E G
authors.initials: EG
authors.lastname: Hahn
mesh_terms: D000236:Adenoma / Q000098:blood supply / Q000000981:diagnostic imaging; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D013961:Thyroid Gland / Q000098:blood supply*; D013963:Thyroid Hormones / Q000097:blood; D013964:Thyroid Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging; D016606:Thyroid Nodule / Q000000981:diagnostic imaging*; D018615:Ultrasonography, Doppler, Color
chemical_list: D013963:Thyroid Hormones