title: Interventional atrioseptostomy by application of monopolar high-frequency alternating current. In vitro evaluation of a new device.
abstract: OBJECTIVE
  The authors evaluate the use of a new device for interventional creation of atrial septal defects (ASD) working with high-frequency alternating current in an in vitro study with porcine atria.
  
  
  METHODS
  The device consists of a symmetrical cage of six superelastic monofile wires, including a microthermistor that is placed via a catheter into a punctured hole in the porcine foramen ovale. The device is used as a differential electrode for monopolar, temperature-controlled application of high-frequency alternating current for thermal modelling of ASD.
  
  
  RESULTS
  Application of current for 60 seconds caused temperature-dependent, sized ASDs.
  
  
  CONCLUSIONS
  In vivo animal studies to evaluate possible side effects and long term patency of the ASDs are justified and warranted.
authors.affiliation: Department of Pediatric Cardiology, Aachen University of Technology, Germany.
authors.forename: R G
authors.initials: RG
authors.lastname: Grabitz
authors.forename: S
authors.initials: S
authors.lastname: Handt
authors.forename: H J
authors.initials: HJ
authors.lastname: Vanopbroeke
authors.forename: M C
authors.initials: MC
authors.lastname: Seghaye
authors.forename: A
authors.initials: A
authors.lastname: Franke
authors.forename: P
authors.initials: P
authors.lastname: Osypka
authors.forename: G
authors.initials: G
authors.lastname: von Bernuth
mesh_terms: D000818:Animals; D017115:Catheter Ablation / Q000379:methods*; D006325:Heart Atria / Q000473:pathology / Q000601:surgery*; D006343:Heart Septal Defects / Q000473:pathology / Q000601:surgery*; D006346:Heart Septum; D066298:In Vitro Techniques; D013552:Swine