title: [Lipoprotein (a) and plasminogen in atherosclerosis].
abstract: The aim of this study was to evaluate plasma levels of lipoprotein (a) [LP(a)] and plasminogen in patients affected with atherosclerotic disease and to understand the mutual relationships. Eighty-four patients affected with atherosclerosis were examined and divided as follows: group I, 24 patients with peripheral arteriopathy; group II, 40 patients with ischemic heart disease (myocardial infarction and/or angina pectoris); group III, 20 patients with multi-infarct dementia; group IV (control group) with 20 healthy young subjects. The results show that Lp(a) plasma levels, in atherosclerotic patients, are higher than 30 mg/dl, while the plasminogen levels are lower than 80 mg/dl. There is an inverse correlation between these two data. Moreover, a different behaviour of Lp(a) and plasminogen rate related to age of patients, to number of atherosclerotic lesions or to acuteness of ischemic heart disease, was observed.
authors.affiliation: Università degli Studi di Roma, La Sapienza, Il Istituto Clinica Medica.
authors.forename: C
authors.initials: C
authors.lastname: Danese
authors.forename: M C
authors.initials: MC
authors.lastname: Borgia
authors.forename: E
authors.initials: E
authors.lastname: Ferranti
authors.forename: E
authors.initials: E
authors.lastname: Zavattaro
authors.forename: A N
authors.initials: AN
authors.lastname: Epiceno
authors.forename: F
authors.initials: F
authors.lastname: Marcianó
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000097:blood; D001157:Arterial Occlusive Diseases / Q000097:blood; D001161:Arteriosclerosis / Q000097:blood*; D003124:Colorimetry; D003327:Coronary Disease / Q000097:blood; D003627:Data Interpretation, Statistical; D015161:Dementia, Multi-Infarct / Q000097:blood; D006801:Humans; D007124:Immunoenzyme Techniques; D017270:Lipoprotein(a) / Q000097:blood*; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood; D010958:Plasminogen / Q000032:analysis*
chemical_list: D017270:Lipoprotein(a); D010958:Plasminogen