title: Incidence of breakpoints in pericentric inversions of chromosome 4.
abstract: We report a new pericentric inversion of chromosome 4 in a female who has had two consecutive fetal losses during the first trimester conception. Cytogenetic findings with GTG-banding revealed a 46,XX,inv(4) (p13q13) karyotype in her peripheral blood cells. The breakpoint on the long arm is different from any other previously described case. A comprehensive bibliography of reported cases with pericentric inversion is also tabulated.
authors.forename: R S
authors.initials: RS
authors.lastname: Verma
authors.forename: S M
authors.initials: SM
authors.lastname: Kleyman
mesh_terms: D019457:Chromosome Breakage; D007446:Chromosome Inversion; D002894:Chromosomes, Human, Pair 4; D005260:Female; D006801:Humans; D007621:Karyotyping