Thyroid autonomy with color-coded image-directed Doppler sonography: internal hypervascularization for the recognition of autonomous adenomas.
In a prospective study, we assessed the possibility of recognizing autonomous adenomas of the thyroid with color-coded image-directed Doppler sonography using internal hypervascularization in thyroid nodules for identification. Fifty-three patients with thyroid nodules underwent additional CCDS examination and nuclear scintigraphy (reference). Of 29 patients having autonomous adenomas, 28 patients presented internal hypervascularization in their nodules resulting in a sensitivity of 96% and a specificity was 75%. Interestingly CCDS detected six adenomas in patients showing normal laboratory data (bTSH, TT3, FT4). CCDS could be used to exclude focal adenomas with a negative predictive value of 94%. The positive predictive value for adenoma was 82%.
Becker
D
D
Department of Medicine I, Friedrich-Alexander-University, Erlangen-Nuremberg, Germany.
Bair
H J
HJ
Becker
W
W
Günter
E
E
Lohner
W
W
Lerch
S
S
Hahn
E G
EG
D000236:Adenoma / Q000098:blood supply / Q000000981:diagnostic imaging; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D013961:Thyroid Gland / Q000098:blood supply*; D013963:Thyroid Hormones / Q000097:blood; D013964:Thyroid Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging; D016606:Thyroid Nodule / Q000000981:diagnostic imaging*; D018615:Ultrasonography, Doppler, Color
D013963:Thyroid Hormones