Superinfected cutaneous angiosarcoma: a highly malignant neoplasm simulating an inflammatory process.
This report describes a patient with a poorly differentiated cutaneous angiosarcoma (CA) of the face superinfected with pseudomonas aeruginosa. Neoplastic cells were positive for CD-34, CD-31 and vimentin, whereas they failed to express other vascular markers such as Factor VIII and Ulex europeaus lectin. The tumor spread rapidly through the skin and the superficial soft tissue before metastasizing. The patient died of disease 6 months after histopathological diagnosis. An autopsy revealed widespread metastases in the lung and the liver. The aim of this report is to call attention to some circumstances in which CA may masquerade as an inflammatory process, delaying the right diagnosis with serious consequences for the patient.
Diaz-Cascajo
C
C
Department of Pathology, Ntra Sra del Pino Hospital, Las Palmas, Canary Islands, Spain.
de la Vega
M
M
Rey-Lopez
A
A
D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006394:Hemangiosarcoma / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology*; D006801:Humans; D007249:Inflammation / Q000473:pathology; D011552:Pseudomonas Infections / Q000175:diagnosis / Q000473:pathology*; D012878:Skin Neoplasms / Q000175:diagnosis / Q000382:microbiology / Q000473:pathology*; D015163:Superinfection / Q000175:diagnosis / Q000473:pathology*