title: [MR dynamic subtraction angiography (MRDSA)].
abstract: We have developed magnetic resonance dynamic subtraction angiography (MRDSA), which depicts the long segments of arteries from the upper abdomen to the lower leg by using a small dose of Gd-DTPA. The lower half of the body was divided into three imaging regions, abdomen, thigh and lower leg, in the order of scanning. The contrast-enhanced three-dimensional breath-hold fast field echo technique with half Fourier acquisition was performed in 3 normal volunteers and 12 patients with vascular diseases (4: abdominal aortic aneurysm, 8: atherosclerotic occlusive disease). The images were reconstructed into composite images by using maximum-intensity-projection postprocessing after the subtraction of precontrast images. A bolus intravenous injection of a small dose of Gd-DTPA (0.02-0.05 mmol/kg) was given, followed by the five sets of scans. The acquisition time of each set was 8 to 16 seconds, and the total dose used in MRDSA was 0.1 to 0.15 mmol/kg. The image quality of MRDSA was satisfactory in 3 normal volunteers and 12 patients with vascular diseases. MRDSA demonstrated aortic aneurysm and atherosclerotic obstruction as clearly as conventional angiography. MRDSA can replace conventional angiography.
authors.affiliation: Department of Radiology, Kurashiki Central Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
authors.forename: M
authors.initials: M
authors.lastname: Dohke
authors.forename: Y
authors.initials: Y
authors.lastname: Amoh
authors.forename: T
authors.initials: T
authors.lastname: Ishimori
authors.forename: A
authors.initials: A
authors.lastname: Okumura
authors.forename: K
authors.initials: K
authors.lastname: Oda
authors.forename: K
authors.initials: K
authors.lastname: Mitsudo
authors.forename: K
authors.initials: K
authors.lastname: Minami
authors.forename: Y
authors.initials: Y
authors.lastname: Dodo
mesh_terms: D015901:Angiography, Digital Subtraction; D017544:Aortic Aneurysm, Abdominal / Q000175:diagnosis; D001161:Arteriosclerosis / Q000175:diagnosis; D019786:Gadolinium DTPA; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives
chemical_list: D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA