title: Cytogenetic characteristics of ectopic pregnancy.
abstract: During a 12 month period, tissue was collected from 30 surgically managed patients presenting with vital ectopic pregnancies. Chorionic villi of the removed tissue were successfully karyotyped by (semi-) direct chromosome technique in 22 cases. Only one abnormal chromosomal complement, a triploidy (69,XXX) was found. As controls, 10 cases of intrauterine pregnancies were investigated, all showing a normal karyotype. These findings do not suggest an important role for chromosome abnormalities in the aetiology of vital ectopic pregnancies.
authors.affiliation: Department of Obstetrics & Gynaecology, University of Amsterdam, The Netherlands.
authors.forename: M
authors.initials: M
authors.lastname: Goddijn
authors.forename: F
authors.initials: F
authors.lastname: van der Veen
authors.forename: G H
authors.initials: GH
authors.lastname: Schuring-Blom
authors.forename: W M
authors.initials: WM
authors.lastname: Ankum
authors.forename: N J
authors.initials: NJ
authors.lastname: Leschot
mesh_terms: D000328:Adult; D002824:Chorionic Villi / Q000648:ultrastructure; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000235:genetics*; D011446:Prospective Studies; D014314:Trisomy; D014960:X Chromosome