Vasoactive intestinal polypeptide containing neurones in monkey medial prefrontal cortex (mPFC): colocalisation with calretinin.
Neurones immunoreactive for vasoactive intestinal polypeptide (VIP) were studied in monkey medial prefrontal cortex. The majority (78.0%) of VIP+ neurones were bipolar cells located mainly in layers 2/3. Calretinin (CR) immunoreactivity was colocalised in 80.5% of VIP+ neurones. Furthermore, VIP+ puncta formed pericellular baskets around GABA immunonegative somata in layers 2/3. These results indicate that VIP/CR are colocalised in some bipolar cells and superficial pyramidal somata are likely targets of VIP+ neurones.
Gabbott
P L
PL
University Department of Pharmacology, Oxford, UK. paul.gabbott@pharm.ox.ac.uk
Bacon
S J
SJ
D000818:Animals; D064032:Calbindin 2; D048429:Cell Size; D005260:Female; D005455:Fluorescent Antibody Technique; D007395:Interneurons / Q000737:chemistry* / Q000166:cytology; D008032:Limbic System / Q000737:chemistry / Q000502:physiology; D008252:Macaca fascicularis; D009419:Nerve Tissue Proteins / Q000032:analysis; D009433:Neural Inhibition / Q000502:physiology; D017397:Prefrontal Cortex / Q000737:chemistry / Q000166:cytology*; D064030:S100 Calcium Binding Protein G / Q000032:analysis*; D014660:Vasoactive Intestinal Peptide / Q000032:analysis*
D064032:Calbindin 2; D009419:Nerve Tissue Proteins; D064030:S100 Calcium Binding Protein G; D014660:Vasoactive Intestinal Peptide