title: Lead poisoning in a dog.
abstract: A case of lead poisoning caused by ingestion of a lead roof-washer is described in a one-year-old, spayed Fox Terrier bitch, presented with nervous signs, and basophilic stippling of red blood cells. Blood concentrations of lead were in the low toxic range. Radiography of the abdomen revealed radio-dense objects in the stomach, which on gastrotomy included a lead roof-washer. Prior to removal of the foreign bodies, the dog showed remarkable improvement on non-specific symptomatic treatment alone, and recovered well after surgery, only to die unexpectedly several hours later. Concentrations of lead in the liver and kidneys were extremely high, and histology revealed typical intracellular inclusions and organ degeneration. In the light of these findings, it is suggested that all cases of suspected or confirmed lead poisoning be given specific chelation therapy.
authors.affiliation: Department of Companion Animal Medicine and Surgery, Faculty of Veterinary Science, Medical University of Southern Africa, Republic of South Africa.
authors.forename: J H
authors.initials: JH
authors.lastname: Williams
authors.forename: M C
authors.initials: MC
authors.lastname: Williams
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000139:chemically induced*; D004285:Dogs; D017809:Fatal Outcome; D005260:Female; D005547:Foreign Bodies / Q000150:complications / Q000662:veterinary*; D007855:Lead Poisoning / Q000662:veterinary*; D013270:Stomach