title: Choriocarcinoma in infant and mother: a case report.
abstract: We present a case of gestational choriocarcinoma that developed in a pregnant woman with metastases to her baby. In this case, severe anemia and hepatomegaly of the baby were noticed after delivery. Despite intensive treatments, the tumor progressed rapidly, and the baby died at the age of 38 days. Accurate diagnosis was made after autopsy. When the baby's mother visited our hospital again at 4 months postpartum, there were widespread multiple metastases to her lungs and liver. We want to emphasize that if a neonate or infant has anemia and/or hepatomegaly, it is necessary to be aware of the possibility of infantile choriocarcinoma with the presence of an occult tumor in the mother and to examine the mother's and infant's hCG levels immediately.
authors.affiliation: Department of Obstetrics and Gynecology, Akita University School of Medicine, Japan.
authors.forename: A E
authors.initials: AE
authors.lastname: Andreitchouk
authors.forename: O
authors.initials: O
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Kodama
authors.forename: M
authors.initials: M
authors.lastname: Morita
authors.forename: T
authors.initials: T
authors.lastname: Sankawa
authors.forename: K
authors.initials: K
authors.lastname: Saito
authors.forename: K
authors.initials: K
authors.lastname: Enomoto
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
mesh_terms: D000328:Adult; D000740:Anemia / Q000209:etiology; D002822:Choriocarcinoma / Q000150:complications / Q000556:secondary*; D017809:Fatal Outcome; D005260:Female; D006529:Hepatomegaly; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D009382:Neoplasms, Unknown Primary; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000150:complications / Q000473:pathology*