[The effect of periodic stretching of the smooth-muscle cells on the expression in them of contractile-phenotype marker proteins].
Cyclic mechanical stretching of the rabbit aortic smooth muscle cells induced a serum-independent increase in the h-caldesmon expression. The expression was more obvious in the cells grown on laminin. The data obtained suggests that the cyclic stretching specifically activates a serum- and matrix-independent expression of h-caldesmon. The mechanical stimulation seems to contribute to the maintenance of the VSMC differentiated phenotype.
Stepanova
O V
OV
Biriukov
K G
KG
Shirinskiĭ
V P
VP
Tkachuk
V A
VA
D000818:Animals; D001011:Aorta / Q000737:chemistry / Q000166:cytology / Q000502:physiology; D001345:Autoradiography; D015415:Biomarkers / Q000032:analysis; D002478:Cells, Cultured; D003470:Culture Media; D004589:Electrophoresis, Disc; D009124:Muscle Proteins / Q000032:analysis / Q000502:physiology*; D009131:Muscle, Smooth, Vascular / Q000737:chemistry / Q000166:cytology / Q000502:physiology*; D010507:Periodicity; D010641:Phenotype; D011817:Rabbits
D015415:Biomarkers; D003470:Culture Media; D009124:Muscle Proteins