title: [Pregnancy and drug dependence].
abstract: A major problem in the treatment of opiate-dependent patients arises due to illicit drug abuse capted with drug dependence and pregnancy. Drug abuse during pregnancy involves a high risk for the mother as well as for the unborn child. Twenty-three pregnant, opiate-dependent women, were enrolled in a 19-month study of the outpatient clinic for drug addiction. The mean age of the subjects was 26.7 years (SD +/- 4.8; range: 20-37 years), the mean duration of opiate dependence was 61.8 months (SD +/- 47.5; range: 12-204 months). Seventeen women were enrolled in a methadone maintenance program and six women were treated with morphine. The babies mean weight at birth was 2746 g (SD +/- 830.1; range: 940-4370), they had no congenital anomalies and all the maintained babies showed an opiate withdrawal syndrome. The treatment yielded in five subjects to a drug-free condition at delivery. The application of morphine might be an alternative in opiate dependent pregnant women and might reduce the additional consumption of illicit drugs during pregnancy.
authors.affiliation: Klinische Abteilung für Allgemeine Psychiatrie, Universitätsklinik für Psychiatrie, Wien.
authors.forename: C
authors.initials: C
authors.lastname: Schneider
authors.forename: G
authors.initials: G
authors.lastname: Fischer
authors.forename: K
authors.initials: K
authors.lastname: Diamant
authors.forename: R
authors.initials: R
authors.lastname: Hauk
authors.forename: L
authors.initials: L
authors.lastname: Pezawas
authors.forename: E
authors.initials: E
authors.lastname: Lenzinger
authors.forename: S
authors.initials: S
authors.lastname: Kasper
mesh_terms: D000284:Administration, Oral; D000328:Adult; D001317:Austria; D003692:Delayed-Action Preparations; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008691:Methadone / Q000008:administration & dosage*; D009020:Morphine / Q000008:administration & dosage*; D009357:Neonatal Abstinence Syndrome / Q000175:diagnosis / Q000209:etiology*; D009293:Opioid-Related Disorders / Q000175:diagnosis / Q000534:rehabilitation*; D010348:Patient Care Team; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000534:rehabilitation*
chemical_list: D003692:Delayed-Action Preparations; D009020:Morphine; D008691:Methadone