[The restrictive syndrome in endomyocardial fibrosis and the effect of enalapril based on acute drug test data].
6 hours after the second dose (5 mg) of enalapril 9 males and 6 females (mean age 34.93 +/- 1.03 years) with endomyocardial fibrosis (EMF) underwent ECG and pulsed Doppler echocardiography to study enalapril effect on cardiohemodynamics. As shown by ventricular diastolic function and systolic flow in the pulmonary artery with estimation of mean pressure in the pulmonary artery according to Kitabatake, enalapril (renitek) affects positively cardiohemodynamics of EMF patients: improvement of ventricular diastolic function occurred in line with a significant fall in the pulmonary artery pressure. It is noted that application of Doppler echocardiography is essential for detection of restriction syndrome.
Bapumiia
M
M
Solomakhina
N I
NI
Sumarokov
A V
AV
D000328:Adult; D000704:Analysis of Variance; D002313:Cardiomyopathy, Restrictive / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D004341:Drug Evaluation; D004452:Echocardiography / Q000187:drug effects; D004562:Electrocardiography / Q000187:drug effects; D004656:Enalapril / Q000008:administration & dosage; D004719:Endomyocardial Fibrosis / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D013577:Syndrome
D004656:Enalapril