title: Primary leiomyosarcoma of the thyroid gland.
abstract: Primary leiomyosarcoma of the thyroid gland is extremely rare, and to the best of our knowledge only five well-documented cases have been reported in the world literature. We herein report a 58-year-old female patient with primary leiomyosarcoma of the thyroid who was successfully treated by total thyroidectomy with a modified neck dissection. Immunohistochemically, the tumor cells showed positive reactivity to alpha-smooth muscle actin and vimentin. Radical surgery was thus considered to be essential in the treatment of this rare but rather aggressive malignancy.
authors.affiliation: Department of Surgery, Ito Hospital, Shibuya-ku, Tokyo, Japan.
authors.forename: O
authors.initials: O
authors.lastname: Ozaki
authors.forename: K
authors.initials: K
authors.lastname: Sugino
authors.forename: T
authors.initials: T
authors.lastname: Mimura
authors.forename: K
authors.initials: K
authors.lastname: Ito
authors.forename: S
authors.initials: S
authors.lastname: Tamai
authors.forename: Y
authors.initials: Y
authors.lastname: Hosoda
mesh_terms: D000199:Actins / Q000032:analysis; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007890:Leiomyosarcoma / Q000737:chemistry / Q000601:surgery*; D008875:Middle Aged; D037981:Neck Dissection; D013964:Thyroid Neoplasms / Q000737:chemistry / Q000601:surgery*; D013965:Thyroidectomy; D014746:Vimentin / Q000032:analysis
chemical_list: D000199:Actins; D014746:Vimentin