Passive and active intracranial translocation of osteosynthesis plates in adolescent minipigs.
On the basis of the clinical and experimental proof that intracranial translocation of osteosynthesis plates occurs in infants after fixation on frontal bone, we conducted an animal study on four adolescent Göttingen minipigs. Our aim was to study the effects on intracranial translocation of two different types of osteosynthesis plates by comparing the plate-bone interface on the intact frontal bone treated with a multiple-point contact plate versus a conventional smooth one, paying special emphasis to the periosteum. Within a few weeks of implantation, osseous regeneration products surrounded the plate. Total invagination of plates with initial intracranial translocation occurred 12 to 16 weeks postimplantation, regardless of plate design. In epiperiosteal fixation, intracranial translocation was delayed. The results revealed two mechanisms at play here: cranial growth-related passive intracranial translocation, which occurs regardless of plate design, and plate-dependent active intracranial translocation. In conclusion, we recommend that all metal osteosynthesis materials implanted in the infant cranium be removed as early as possible (within 3 months).
Hönig
J F
JF
Department of Maxillofacial Surgery, University Hospital and Medical School, Göttingen, Germany.
Merten
H A
HA
Luhr
H G
HG
D000818:Animals; D001860:Bone Plates / Q000009:adverse effects*; D001862:Bone Resorption / Q000150:complications / Q000209:etiology; D003399:Craniotomy / Q000009:adverse effects / Q000295:instrumentation; D005260:Female; D005548:Foreign-Body Migration / Q000209:etiology; D005624:Frontal Bone / Q000601:surgery*; D008856:Microscopy, Fluorescence; D010012:Osteogenesis / Q000502:physiology; D010521:Periosteum / Q000601:surgery; D019736:Prostheses and Implants / Q000009:adverse effects; D013552:Swine; D013556:Swine, Miniature; D014025:Titanium
D014025:Titanium