title: Recent enhancements to the Blocks Database servers.
abstract: The Blocks Database contains multiple alignments of conserved regions in protein families which can be searched by e-mail (blocks@blocks.fhcrc.org) and World Wide Web (http://blocks.fhcrc.org/ ) servers to classify protein and nucleotide sequences. Recent enhancements to the servers include: (i) improved calculation of position-specific scoring matrices from blocks; (ii) availability of the Prints protein fingerprint database for searching in Blocks format; (iii) a representative sequence biased towards the Blocks of a protein family; (iv) a tree constructed from the Blocks of a protein family; (v) links to related World Wide Web pages for a family; and (vi) the new Local Alignment of Multiple Alignments (LAMA) method to search a block against a database of blocks.
authors.affiliation: Fred Hutchinson Cancer Research Center, 1124 Columbia Street, Seattle, WA 98104, USA.
authors.forename: J G
authors.initials: JG
authors.lastname: Henikoff
authors.forename: S
authors.initials: S
authors.lastname: Pietrokovski
authors.forename: S
authors.initials: S
authors.lastname: Henikoff
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003195:Computer Communication Networks; D016208:Databases, Factual; D006801:Humans; D008969:Molecular Sequence Data; D011506:Proteins / Q000235:genetics*; D016415:Sequence Alignment / Q000379:methods*
chemical_list: D011506:Proteins