title: The complexities of T-cell co-stimulation: CD28 and beyond.
authors.affiliation: Ben May Institute for Cancer Research, Department of Pathology, University of Chicago, IL 60637, USA.
authors.forename: A I
authors.initials: AI
authors.lastname: Sperling
authors.forename: J A
authors.initials: JA
authors.lastname: Bluestone
mesh_terms: D000069594:Abatacept; D000818:Animals; D015703:Antigens, CD / Q000378:metabolism*; D000943:Antigens, Differentiation / Q000378:metabolism*; D001327:Autoimmune Diseases / Q000276:immunology; D018122:B7-1 Antigen / Q000378:metabolism; D051940:B7-2 Antigen; D018106:CD28 Antigens / Q000378:metabolism; D060908:CTLA-4 Antigen; D006084:Graft Rejection / Q000276:immunology; D018796:Immunoconjugates; D007166:Immunosuppressive Agents / Q000378:metabolism*; D008024:Ligands; D008213:Lymphocyte Activation; D008562:Membrane Glycoproteins / Q000378:metabolism; D051379:Mice; D018448:Models, Immunological; D011485:Protein Binding; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D015703:Antigens, CD; D000943:Antigens, Differentiation; D018122:B7-1 Antigen; D051940:B7-2 Antigen; D018106:CD28 Antigens; D060908:CTLA-4 Antigen; C497965:Cd86 protein, mouse; C556707:Ctla4 protein, mouse; D018796:Immunoconjugates; D007166:Immunosuppressive Agents; D008024:Ligands; D008562:Membrane Glycoproteins; D000069594:Abatacept