Chorionic villus sampling and end-artery disruption of the fetus.
A fetus with transverse limb reduction defects and jejunal atresia after exposure to chorionic villus sampling (CVS) at 9 weeks of amenorrhoea is described. A theory involving disruption of end-arteries due to the CVS procedure is suggested.
Luijsterburg
A J
AJ
Department of Anatomy, University Hospital Rotterdam, Erasmus University Rotterdam, The Netherlands.
van der Zee
D C
DC
Gaillard
J L
JL
Los
F J
FJ
Brandenburg
H
H
van Haeringen
A
A
Vermeij-Keers
C
C
D000328:Adult; D001344:Autopsy; D015193:Chorionic Villi Sampling / Q000009:adverse effects*; D005121:Extremities / Q000196:embryology / Q000473:pathology*; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000196:embryology*; D005333:Fetus / Q000002:abnormalities* / Q000473:pathology; D006801:Humans; D007583:Jejunum / Q000002:abnormalities; D007751:Labor, Induced; D017880:Limb Deformities, Congenital; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D016216:Ultrasonography, Prenatal