title: Diffuse hypertrichosis during treatment with 5% topical minoxidil.
abstract: Five women affected by androgenetic alopecia developed severe hypertrichosis of the face and limbs after 2-3 months of treatment with 5% topical minoxidil. Minoxidil was discontinued and in all patients the hypertrichosis disappeared from the face and arms after 1-3 months, and from legs after 4-5 months. Systemic absorption of minoxidil, and a high sensitivity to minoxidil of the follicular apparatus in these areas, is hypothesized.
authors.affiliation: Department of Dermatology, University of Borogna, Italy.
authors.forename: A M
authors.initials: AM
authors.lastname: Peluso
authors.forename: C
authors.initials: C
authors.lastname: Misciali
authors.forename: C
authors.initials: C
authors.lastname: Vincenzi
authors.forename: A
authors.initials: A
authors.lastname: Tosti
mesh_terms: D000279:Administration, Cutaneous; D000293:Adolescent; D000328:Adult; D000505:Alopecia / Q000188:drug therapy*; D005260:Female; D006801:Humans; D006983:Hypertrichosis / Q000139:chemically induced* / Q000473:pathology; D008875:Middle Aged; D008914:Minoxidil / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D012869:Skin Absorption
chemical_list: D008914:Minoxidil