The genetics of aging.
There is no aging program, nor is there an aging gene. Instead, we age because evolution has no reason to protect us against unwelcome actions of multiple genes late in life. Still, every discovery of a harmful mutation or polymorphism raises at least the theoretical possibility of other, beneficial alleles- and offers clues for understanding the biomolecular mechanisms that underlie senescence.
Martin
G M
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Department of Pathology, Alzheimer's Disease Research Center, University of Washington School of Medicine, Seattle, USA.
D000375:Aging / Q000235:genetics*; D000544:Alzheimer Disease / Q000235:genetics*; D000818:Animals; D006801:Humans; D008967:Molecular Biology; D014898:Werner Syndrome / Q000235:genetics*