title: Superior vena cava thrombosis and chylothorax: relationship in pediatric nephrotic syndrome.
abstract: We report a 40-month-old black male with nephrotic syndrome who developed chylothorax associated with superior vena cava (SVC) thrombosis. To our knowledge, this is the third reported case of spontaneous SVC thrombosis in a nephrotic patient and the first in which chylothorax was also present. Ultrasonography of the pleura and thoracic vasculature was invaluable in making the diagnosis and monitoring the resolution of this condition during treatment. Contrary to previous reports, thoracic chylous effusions complicating uncontrolled nephrotic syndrome do not originate exclusively as a consequence of abdominal pathology, but rather as this case demonstrates, they can occur from lymphatic obstruction caused by thoracic vein thrombosis.
authors.affiliation: Department of Pediatrics, Medical College of Georgia, Augusta 30912, USA.
authors.forename: J
authors.initials: J
authors.lastname: Hanna
authors.forename: E
authors.initials: E
authors.lastname: Truemper
authors.forename: E
authors.initials: E
authors.lastname: Burton
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D002916:Chylothorax / Q000000981:diagnostic imaging / Q000209:etiology*; D004232:Diuretics / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D009404:Nephrotic Syndrome / Q000150:complications* / Q000000981:diagnostic imaging; D010996:Pleural Effusion / Q000150:complications / Q000188:drug therapy; D011014:Pneumonia / Q000000981:diagnostic imaging / Q000209:etiology; D013479:Superior Vena Cava Syndrome / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology*; D014463:Ultrasonography
chemical_list: D000925:Anticoagulants; D004232:Diuretics