Mucosal immunology and models of mucosal HIV infection.
The mucosa associated lymphoid tissue regulates and coordinates immune responses against mucosal pathogens. Mucosal tissues are the major targets exposed to HIV during transmission. In this paper we describe in vitro models of HIV mucosal infection using human explants to investigate target cells within this tissue.
Griffin
G E
GE
Departamento de Imunologia, Instituto Oswaldo Cruz, Rio de Janeiro, Brasil.
Castello-Branco
L R
LR
Ortigão-de-Sampaio
M B
MB
Shattock
R
R
D000328:Adult; D002584:Cervix Uteri / Q000276:immunology*; D005260:Female; D015658:HIV Infections / Q000276:immunology*; D006801:Humans; D018928:Immunity, Mucosal; D066298:In Vitro Techniques; D007413:Intestinal Mucosa / Q000276:immunology*; D008221:Lymphoid Tissue / Q000276:immunology*; D008297:Male; D009092:Mucous Membrane / Q000276:immunology