Inherited disorders: a genetic primer.
Identification of inherited or genetic disorders has important implications for the prognosis and treatment of affected infants. This article addresses the three most common categories of genetic disorders--single-gene defects, chromosomal abnormalities, and multifactorial conditions. The principles of transmission, risk of inheritance, and clinical significance of each category are discussed, with examples of inherited disorders in each category.
Pickler
R H
RH
Virginia Commonwealth University, Richmond 23298-0567, USA. rpickler@gems.vcu.edu
Munro
C L
CL
D005260:Female; D005799:Genes, Dominant; D005808:Genes, Recessive; D030342:Genetic Diseases, Inborn / Q000235:genetics* / Q000451:nursing; D008040:Genetic Linkage; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D017283:Neonatal Nursing; D010375:Pedigree; D017354:Point Mutation; D012730:Sex Chromosomes