title: DNA-repair enzymes.
abstract: Recent crystallographic studies of DNA-repair enzymes have provided the structural basis for the recognition of damaged DNA. The results imply that flipping out of the base is a common and crucial event in DNA repair. Two classes of repair enzymes that recognize distinct types of damage may exist. DNA-repair enzymes that share similar folds and DNA binding motifs have been proposed to belong to a superfamily.
authors.affiliation: International Institute for Advanced Research, Central Research Laboratories, Matsushita Electric Industrial, 3-4 Hikari-dai, Seika, Kyoto 619-02, Japan. dmitry@crl.mei.co.jp
authors.forename: D G
authors.initials: DG
authors.lastname: Vassylyev
authors.forename: K
authors.initials: K
authors.lastname: Morikawa
mesh_terms: D004247:DNA / Q000378:metabolism; D004249:DNA Damage; D004260:DNA Repair; D004798:Enzymes / Q000737:chemistry / Q000378:metabolism*; D011487:Protein Conformation; D013379:Substrate Specificity
chemical_list: D004798:Enzymes; D004247:DNA