[The cardiohemodynamic characteristics of the action of obzidan in patients with an artificial pacemaker and ischemic heart disease with different types of blood circulation].
The effect of a single administration and a 2-week course of obsidan treatment on cardiohemodynamics was studied in patients with an artificial cardiac pacemaker and a fixed rate of electrocardiostimulation. Echocardiography showed that obsidan reduced heart contractility and pump function in patients with an artificial cardiac pacemaker and different types of blood circulation (hyper-, eu-, and hypokinetic). The cardiohemodynamic effects of obsidan were found to be dependent on the initial type of circulation and the features of intracardiac hemodynamics in different modes of cardiac pacing.
Iskenderov
B G
BG
Tatarchenko
I P
IP
D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000503:physiopathology* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000503:physiopathology* / Q000628:therapy; D010138:Pacemaker, Artificial; D011433:Propranolol / Q000627:therapeutic use*
D000889:Anti-Arrhythmia Agents; D011433:Propranolol