[The effect of a peptide preparation made from ovaries on reproductive function].
A study was done on the action of the low molecular peptide preparation isolated from cow ovaries by the acetic acid extraction, on the rat ovary function. It was revealed that this preparation: 1) does not possess the gonadotrophic activity; 2) enhances the sensitivity of immature rat ovaries to the human chorionic gonadotrophin; 3) increases the number of ovulating oocytes in neonatal androgenized rats in gonadotrophic stimulation of the ovary function; 4) does not influence the character and duration of the estrous cycle in intact adult rats.
Zelenina
N V
NV
Lesik
E A
EA
Korkhov
V V
VV
D000818:Animals; D000831:Animals, Newborn; D002417:Cattle; D006063:Chorionic Gonadotropin / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D004971:Estrus / Q000187:drug effects; D005260:Female; D010053:Ovary / Q000737:chemistry*; D010455:Peptides / Q000302:isolation & purification / Q000494:pharmacology*; D051381:Rats; D012098:Reproduction / Q000187:drug effects*; D012741:Sexual Maturation / Q000187:drug effects; D013739:Testosterone / Q000494:pharmacology
D006063:Chorionic Gonadotropin; D010455:Peptides; D013739:Testosterone