title: [Epidural anesthesia for herniorrhaphy in a patient with severe dilated cardiomyopathy (DCM) under pimobendan control].
abstract: A 60-year-old man with severe DCM was scheduled for a herniorrhaphy under epidural anesthesia using fentanyl. Three months prior to operation, the patient suffered heart failure associated with life-threatening ventricular arrhythmia. The former was successfully treated with pimobendan as the main constituent of medication, but the latter was not responsive to various antiarrhythmic drugs with the exception of aprindine. On the day of operation and for two days postoperatively, pimobendan was administered daily. A sudden drop in systemic blood pressure and central venous pressure (CVP) during anesthesia, as well as the tendency to hypotensive status in the postoperative period were well regulated with continuous infusion of dopamine and dobutamine via CVP catheter probably due to the effect of up-regulation of pimobendan, together with adjustment of the volume of intravenous fluids. No dangerous ventricular arrhythmia were observed. Thereafter the patient made uneventful progress and was discharged on the 8th postoperative day.
authors.affiliation: Juntendo University Urayasu Hospital, Department of Anesthesiology, Chiba.
authors.forename: M
authors.initials: M
authors.lastname: Shiraishi
authors.forename: K
authors.initials: K
authors.lastname: Murayama
authors.forename: K
authors.initials: K
authors.lastname: Hanzawa
authors.forename: K
authors.initials: K
authors.lastname: Warabi
authors.forename: Y
authors.initials: Y
authors.lastname: Kamiyama
mesh_terms: D000767:Anesthesia, Epidural; D002311:Cardiomyopathy, Dilated / Q000150:complications / Q000188:drug therapy*; D002316:Cardiotonic Agents / Q000008:administration & dosage*; D004280:Dobutamine / Q000008:administration & dosage; D004298:Dopamine / Q000008:administration & dosage; D005283:Fentanyl; D006333:Heart Failure / Q000150:complications / Q000188:drug therapy; D006552:Hernia, Inguinal / Q000150:complications / Q000601:surgery*; D006801:Humans; D007022:Hypotension / Q000188:drug therapy; D007431:Intraoperative Complications / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy; D011724:Pyridazines / Q000008:administration & dosage*
chemical_list: D002316:Cardiotonic Agents; D011724:Pyridazines; C041648:pimobendan; D004280:Dobutamine; D005283:Fentanyl; D004298:Dopamine