title: Recovery of portal blood flow after percutaneous transhepatic biliary drainage in patients with obstructive jaundice.
abstract: Using an ultrasonic Doppler system, we prospectively studied the changes in portal venous flow (PVF) following percutaneous transhepatic biliary drainage (PTBD) and evaluated the correlation between PVF and liver function in 10 patients with obstructive jaundice. The patients were divided into two groups according to their rate of decrease in serum bilirubin ("b"). Group A comprised 5 patients with a "b" of less than -0.1, while group B consisted of 5 patients who did not meet this criterion. The mean PVF increased following PTBD (P < 0.01). The increase in PVF was due to an increase in the maximum velocity of the portal vein (Vmax). The rate of increase in the Vmax in group A was significantly higher than that in group B on both the 7th and 14th postdrainage days (P < 0.05). The rate of increase in the Vmax correlated significantly with the rate of decrease in the serum bilirubin concentration (P < 0.01). Based on the above findings, we conclude that measuring the Vmax by Doppler ultrasonography is useful in evaluating the liver function in patients with obstructive jaundice.
authors.affiliation: First Department of Surgery, Nagoya University School of Medicine, Showa-ku, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kanda
authors.forename: Y
authors.initials: Y
authors.lastname: Nimura
authors.forename: A
authors.initials: A
authors.lastname: Yasui
authors.forename: S
authors.initials: S
authors.lastname: Nakano
authors.forename: S
authors.initials: S
authors.lastname: Kumada
authors.forename: S
authors.initials: S
authors.lastname: Shionoya
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001663:Bilirubin / Q000097:blood; D002779:Cholestasis / Q000503:physiopathology / Q000628:therapy*; D004322:Drainage / Q000379:methods*; D005260:Female; D006801:Humans; D008099:Liver / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011168:Portal System / Q000000981:diagnostic imaging / Q000502:physiology*; D011446:Prospective Studies; D012039:Regional Blood Flow; D018608:Ultrasonography, Doppler
chemical_list: D001663:Bilirubin