[The growth characteristics of the liver parenchyma in the pre- and postnatal ontogeny of the guinea pig].
The growth dynamics of guinea pig liver parenchyma in prenatal and postnatal ontogeny was investigated with morphometrical and stereological methods. The results show that parenchyma growth in prenatal period is determined by high proliferative activity of prehepatocytes, which sizes remain nearly constant. On the contrary in postnatal period hepatocytes' hypertrophy becomes the main factor of parenchyma growth. The specificity of prenatal liver growth can be determined by a necessity to maintain geometrical stability of its "hemopoietic stroma".
Nikonenko
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D000375:Aging; D000818:Animals; D002455:Cell Division; D005865:Gestational Age; D006168:Guinea Pigs; D008099:Liver / Q000166:cytology / Q000196:embryology* / Q000254:growth & development*