Radiation induced intracranial leiomyosarcoma: its histopathological features.
This is a case of intracranial sarcoma which was recognized 23 years after irradiation therapy for pituitary adenoma. Four operations were performed because of recurrences with a short interval between each operation. Immunohistochemically, the tumour cells were stained for smooth muscle actin, human muscle actin and vimentin. It was verified as a leiomyosarcoma. This report is the first case of intracranial leiomyosarcoma associated with radiation therapy in pituitary adenoma.
Niwa
J
J
Department of Neurosurgery, Sapporo Medical University, Japan.
Hashi
K
K
Minase
T
T
D000236:Adenoma / Q000532:radiotherapy; D001932:Brain Neoplasms / Q000150:complications* / Q000473:pathology; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000532:radiotherapy; D011832:Radiation Injuries; D011878:Radiotherapy / Q000009:adverse effects*