title: Membrane immunoglobulin-associated molecules on channel catfish B lymphocytes.
abstract: Membrane immunoglobulin (mIgM) on the surface of channel catfish B lymphocytes is non-covalently associated with 64 and 70 kDa molecules which are composed of covalent 32 kDa dimers and covalent 45/25 kDa subunits, respectively. Cross-linking of mIgM on catfish B cells leads to rapid phosphorylation of tyrosine residues in these presumed accessory as well as numerous other cytoplasmic molecules. These data indicate that fish likely use a signal transduction system containing elements similar to those of mammalian B cells.
authors.affiliation: Department of Microbiology, University of Mississippi Medical Center, Jackson 39216, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Rycyzyn
authors.forename: M R
authors.initials: MR
authors.lastname: Wilson
authors.forename: G W
authors.initials: GW
authors.lastname: Warr
authors.forename: L W
authors.initials: LW
authors.lastname: Clem
authors.forename: N W
authors.initials: NW
authors.lastname: Miller
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D007059:Ictaluridae / Q000276:immunology*; D008565:Membrane Proteins / Q000276:immunology* / Q000378:metabolism*; D010766:Phosphorylation; D011485:Protein Binding / Q000276:immunology; D011947:Receptors, Antigen, B-Cell / Q000276:immunology* / Q000378:metabolism*
chemical_list: D008565:Membrane Proteins; D011947:Receptors, Antigen, B-Cell