[Brain glycolipids in rats after disulfiram administration].
The effect of disulfiram (teturam, antabus) (200 mg/kg, intragastrically) on the rat brain glycolipid structure was studied. It was found that disulfiram increased the contents of cerebrosides I and III in nervous tissue. The administration of alcohol (1 g/kg, 20% solution, intraperitoneally), with disulfiram being simultaneously administered, was accompanied by increased levels of brain cerebrosides I and II.
Selevich
M I
MI
Lelevich
V V
VV
D000427:Alcohol Deterrents / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D001923:Brain Chemistry / Q000187:drug effects; D004221:Disulfiram / Q000008:administration & dosage / Q000494:pharmacology*; D000431:Ethanol / Q000008:administration & dosage; D006017:Glycolipids / Q000032:analysis / Q000378:metabolism*; D008297:Male; D051381:Rats; D013997:Time Factors
D000427:Alcohol Deterrents; D006017:Glycolipids; D000431:Ethanol; D004221:Disulfiram