title: The guide RNA database.
abstract: The RNA editing process in protozoan parasites is controlled by small RNA molecules known as guide RNAs (gRNAs). The gRNA database is a comprehensive compilation of published guide RNA sequences from eight different kinetoplastid organisms. In addition to the RNA primary sequences, information on the gene localization, the experimental verification of the transcripts, and literature citations are provided. Accessory information includes the secondary structures of fourTrypanosoma bruceigRNAs as well as a computer modelled three dimensional gRNA structure. The database is made available as a hypertext document accessible via the World Wide Web (WWW) or from the authors in a printed form.
authors.affiliation: Laboratorium für Molekulare Biologie, Genzentrum der LMU München am MPI für Biochemie, Am Klopferspitz 18, 82152 Martinsried, Germany.
authors.forename: A E
authors.initials: AE
authors.lastname: Souza
authors.forename: T
authors.initials: T
authors.lastname: Hermann
authors.forename: H U
authors.initials: HU
authors.lastname: Göringer
mesh_terms: D000818:Animals; D001483:Base Sequence; D016208:Databases, Factual; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D017394:RNA, Guide, Kinetoplastida / Q000737:chemistry / Q000235:genetics*; D016053:RNA, Protozoan / Q000235:genetics*; D014346:Trypanosoma brucei brucei / Q000235:genetics
chemical_list: D016053:RNA, Protozoan; D017394:RNA, Guide, Kinetoplastida