title: Identification of nucleotide sequences that regulate transcription of the MCF13 murine leukemia virus long terminal repeat in activated T cells.
abstract: The region downstream of the enhancer (DEN) of the long terminal repeat of the mink cell focus-forming murine leukemia virus is important for viral pathogenicity. Another important activity of DEN is its control of transcription in activated T cells, and we have determined that an NF-kappaB site is critical for this activity.
authors.affiliation: Department of Immunology and Microbiology, Wayne State University, Detroit, Michigan 48201, USA. fyoshi@med.wayne.edu
authors.forename: F K
authors.initials: FK
authors.lastname: Yoshimura
authors.forename: M
authors.initials: M
authors.lastname: Cankovic
authors.forename: R
authors.initials: R
authors.lastname: Smeltz
authors.forename: S
authors.initials: S
authors.lastname: Ibrahim
mesh_terms: D000818:Animals; D015967:Gene Expression Regulation, Viral; D006801:Humans; D015759:Ionomycin / Q000494:pharmacology; D019169:Jurkat Cells; D008213:Lymphocyte Activation; D008908:Mink Cell Focus-Inducing Viruses / Q000235:genetics* / Q000472:pathogenicity; D016296:Mutagenesis; D016328:NF-kappa B / Q000378:metabolism; D012045:Regulatory Sequences, Nucleic Acid; D012091:Repetitive Sequences, Nucleic Acid; D013601:T-Lymphocytes / Q000187:drug effects / Q000378:metabolism*; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D014158:Transcription, Genetic
chemical_list: D016328:NF-kappa B; D015759:Ionomycin; D013755:Tetradecanoylphorbol Acetate