[The limitation of lipid hyperperoxidation and the prevention of stressor damages to the heart by glycine derivatives].
It is shown that glycine derivatives decrease considerably activation of lipid peroxidation in stress, reduce the duration of the alarm stage of the stress reaction, and limit the stress damage to the heart. The idea of the organism's glycinergic stress limiting system is suggested.
Malyshev
V V
VV
Oshchepkova
O M
OM
Seminskiĭ
I Zh
IZh
Nefedova
T V
TV
Morozova
T P
TP
D000818:Animals; D009202:Cardiomyopathies / Q000209:etiology / Q000378:metabolism / Q000517:prevention & control*; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D005215:Fasting / Q000502:physiology; D005998:Glycine / Q000031:analogs & derivatives* / Q000494:pharmacology / Q000627:therapeutic use; D006321:Heart / Q000187:drug effects; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D009206:Myocardium / Q000378:metabolism; D011760:Pyrrolidinones / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000150:complications / Q000378:metabolism / Q000517:prevention & control*; D013997:Time Factors
C103879:4-phenyl-2-oxo-1-pyrrolidinylacetylurea; D011760:Pyrrolidinones; C097888:N,N-dibenzylglycine; D005998:Glycine