title: [Sinus bradycardia secondary to systemic pentamidine].
abstract: Systemic side effects caused by parenteral pentamidine are frequent. They can be severe and life-threatening. Intravenous pentamidine may cause a variety of abnormalities in the cardiac conduction system as tachyarrhythmias, hypotension and/or non-specific ECG changes (a long corrected QT interval). There is only one case of previously reported bradyarrhythmias in an HIV-infected patient. We present a new adverse effect associated with intravenous pentamidine therapy, and to the best of our knowledge, this is the first reported case of sinus bradycardia in a patient who is not HIV-infected.
authors.affiliation: Sección de Neumología, Hospital General de Albacete.
authors.forename: M
authors.initials: M
authors.lastname: Izquierdo Patrón
authors.forename: C
authors.initials: C
authors.lastname: Lafuente
authors.forename: M
authors.initials: M
authors.lastname: Haro Estarriol
authors.forename: M
authors.initials: M
authors.lastname: Arévalo González
mesh_terms: D001919:Bradycardia / Q000139:chemically induced* / Q000175:diagnosis; D002908:Chronic Disease; D005260:Female; D018023:HIV Seronegativity; D006801:Humans; D007275:Injections, Intravenous; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy; D008875:Middle Aged; D010419:Pentamidine / Q000008:administration & dosage / Q000009:adverse effects*; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy / Q000209:etiology
chemical_list: D010419:Pentamidine