[Sensory Jacksonian seizures as initial manifestation of sarcoidosis].
A 46-year old patient is reported presenting with somatosensory focal seizures of either arm as the only manifestation of an otherwise clinically inapparent sarcoidosis. MRI showed signs of a granulomatous leptomeningeal affection. Histological examination of a meningeal biopsy proved the diagnosis of sarcoidosis by demonstrating noncaseating granulomas. There was no other clinical manifestation of sarcoidosis. Chest X-ray was normal and the serum level of angiotensin-converting-enzyme was only slightly elevated. The CD4/CD8 ratio in the bronchoalveolar lavage cell population, however, was clearly abnormal, supporting the role of this diagnostic tool in the diagnosis of sarcoidosis.
Meincke
U
U
Neurologische Klinik, RWTH Aachen.
Mull
M
M
Weis
J
J
Töpper
R
R
D001706:Biopsy; D001927:Brain Diseases / Q000150:complications* / Q000473:pathology; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology; D016516:CD4-CD8 Ratio; D003937:Diagnosis, Differential; D004828:Epilepsies, Partial / Q000209:etiology* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008578:Meninges / Q000473:pathology; D008875:Middle Aged; D012507:Sarcoidosis / Q000150:complications* / Q000473:pathology; D017565:Sarcoidosis, Pulmonary / Q000150:complications / Q000473:pathology; D014057:Tomography, X-Ray Computed