Interventional atrioseptostomy by application of monopolar high-frequency alternating current. In vitro evaluation of a new device.
OBJECTIVE
The authors evaluate the use of a new device for interventional creation of atrial septal defects (ASD) working with high-frequency alternating current in an in vitro study with porcine atria.


METHODS
The device consists of a symmetrical cage of six superelastic monofile wires, including a microthermistor that is placed via a catheter into a punctured hole in the porcine foramen ovale. The device is used as a differential electrode for monopolar, temperature-controlled application of high-frequency alternating current for thermal modelling of ASD.


RESULTS
Application of current for 60 seconds caused temperature-dependent, sized ASDs.


CONCLUSIONS
In vivo animal studies to evaluate possible side effects and long term patency of the ASDs are justified and warranted.
Grabitz
R G
RG
Department of Pediatric Cardiology, Aachen University of Technology, Germany.
Handt
S
S
Vanopbroeke
H J
HJ
Seghaye
M C
MC
Franke
A
A
Osypka
P
P
von Bernuth
G
G
D000818:Animals; D017115:Catheter Ablation / Q000379:methods*; D006325:Heart Atria / Q000473:pathology / Q000601:surgery*; D006343:Heart Septal Defects / Q000473:pathology / Q000601:surgery*; D006346:Heart Septum; D066298:In Vitro Techniques; D013552:Swine