[Phenotypic expression of the Ca2+-dependence trait in recombinant cells of Yersinia pestis (Lehmann, Neumann)].
A conceptual model of the Yersinia pestis Ca(2+)-dependence mechanism is proposed. The model is based on data from analyses of peculiarities of recombinant cells of this plague-causing agent carrying the cloned first Bg/II fragment of the Ca(2+)-dependence plasmid (pCaD) and a combination of this fragment and other plasmid pCaD fragments. The data obtained also allowed a revision of the role of the lcr GVH locus of pCaD in this phenomenon.
Mozharov
O T
OT
Savostina
E P
EP
Anisimov
P I
PI
Shvedun
G P
GP
Popov
Iu A
IuA
D002118:Calcium / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects / Q000235:genetics; D002874:Chromosome Mapping; D003470:Culture Media; D004274:DNA, Recombinant / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial / Q000502:physiology*; D006358:Hot Temperature; D010641:Phenotype; D010957:Plasmids; D014774:Virulence; D015010:Yersinia pestis / Q000187:drug effects / Q000235:genetics* / Q000472:pathogenicity
D003470:Culture Media; D004274:DNA, Recombinant; D002118:Calcium