Histopathologic prognostic factors in early stage cervical carcinoma.
The pathologist makes extensive assessments in cases of early stage carcinoma of the cervix. The following parameters are known to affect prognosis: capillary-lymphatic space invasion, depth of invasion, size of gross tumor, histologic type, grade (in adenocarcinoma), involvement by tumor of pelvic or para-aortic lymph nodes, and lymphoid response and immune status. These findings, along with clinical stage, best predict tumor behavior. Other observations are under investigation to evaluate their usefulness.
Benda
J A
JA
Department of Pathology, University of Iowa, Iowa City, USA.
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000401:mortality / Q000473:pathology*; D005260:Female; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D009367:Neoplasm Staging; D011237:Predictive Value of Tests; D011379:Prognosis; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000401:mortality / Q000473:pathology*