title: Subjective complaints versus actual cognitive deficits in predominantly symptomatic HIV-1 seropositive individuals.
abstract: The relationship of self-reported cognitive, motor, and affective complaints to actual neuropsychological functioning was explored in a cohort of predominantly symptomatic HIV-1 seropositive individuals. Ninety-two symptomatic HIV-1 infected subjects were questioned about complaints common in HIV infection and were assessed with a comprehensive neuropsychological test battery. No relationship was found between subjective complaints and cognitive functioning, yet a significant relationship was found between self-reported difficulties and formal measures of affect and mood. Failure to show a relationship between self-reported cognitive status and actual neuropsychological functioning in this cohort suggests that complaints of cognitive decline may be attributable to emotional factors.
authors.affiliation: Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, School of Medicine, USA.
authors.forename: L H
authors.initials: LH
authors.lastname: Moore
authors.forename: W G
authors.initials: WG
authors.lastname: van Gorp
authors.forename: C H
authors.initials: CH
authors.lastname: Hinkin
authors.forename: M J
authors.initials: MJ
authors.lastname: Stern
authors.forename: T
authors.initials: T
authors.lastname: Swales
authors.forename: P
authors.initials: P
authors.lastname: Satz
mesh_terms: D000328:Adult; D003072:Cognition Disorders / Q000209:etiology / Q000523:psychology*; D004644:Emotions; D015658:HIV Infections / Q000150:complications / Q000523:psychology*; D006679:HIV Seropositivity / Q000150:complications / Q000523:psychology*; D015497:HIV-1; D006801:Humans; D007802:Language; D008297:Male; D008568:Memory / Q000187:drug effects; D019964:Mood Disorders / Q000523:psychology; D009483:Neuropsychological Tests; D010465:Perception / Q000502:physiology; D011569:Psychiatric Status Rating Scales; D011597:Psychomotor Performance / Q000502:physiology