title: Erosive pustular dermatosis of the scalp in skin grafts: report of three cases.
abstract: Three patients developed erosive pustular dermatosis of the scalp (EPDS). Two of them, both males, had previously undergone surgical excision for squamous cell carcinoma and basal cell carcinoma, and a female experienced avulsive trauma of the scalp. The erosive lesions and crusts were located at the site of a skin graft; microbiological cultures were negative for bacterial and fungal growth. Histological examination ruled out pustular bullous disorders. Topical therapy with corticosteroids and antibiotics resulted in clinical remission in only 2 cases. The third case showed a tendency to recur despite numerous therapeutic attempts with oral dapsone and isotretinoin. We conclude that surgical trauma is a possible cause of EPDS. Our patients seem to be the first reported cases of EPDS in skin grafts following plastic surgical procedures.
authors.affiliation: Department of Dermatology, Faculty of Medicine, Sassari University, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Ena
authors.forename: M
authors.initials: M
authors.lastname: Lissia
authors.forename: G M
authors.initials: GM
authors.lastname: Doneddu
authors.forename: G V
authors.initials: GV
authors.lastname: Campus
mesh_terms: D000279:Administration, Cutaneous; D000284:Administration, Oral; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001419:Bacteria / Q000302:isolation & purification; D001623:Betamethasone / Q000008:administration & dosage / Q000627:therapeutic use; D002280:Basal Cell Carcinoma / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000601:surgery; D003622:Dapsone / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005658:Fungi / Q000302:isolation & purification; D005839:Gentamicins / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage / Q000627:therapeutic use; D007641:Keratolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012074:Remission Induction; D012535:Scalp / Q000293:injuries / Q000601:surgery; D012536:Scalp Dermatoses / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D012878:Skin Neoplasms / Q000601:surgery; D016038:Skin Transplantation / Q000009:adverse effects*
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D005839:Gentamicins; D007641:Keratolytic Agents; D003622:Dapsone; D001623:Betamethasone; D015474:Isotretinoin