title: A case of malignant fibrous histiocytoma of the lung arising as a third primary tumor.
abstract: A case of primary malignant myxoid fibrous histiocytoma of the lung presenting as a solitary lung nodule in a 61-year-old man is presented. This tumor arose in a patient with a transitional-cell carcinoma of the urinary bladder and a well differentiated squamous-cell carcinoma of the larynx. The differential diagnosis between a primary lung tumor, versus a solitary metastasis is difficult and was supported by histological features and the lack of epithelial properties proved by immunohistochemistry. Tobacco was the only etiologic factor known in the patient.
authors.affiliation: Department of Anatomical Pathology, Marqués de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain.
authors.forename: J J
authors.initials: JJ
authors.lastname: Gómez-Román
authors.forename: J F
authors.initials: JF
authors.lastname: Val-Bernal
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology; D002295:Carcinoma, Transitional Cell / Q000473:pathology; D003937:Diagnosis, Differential; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary / Q000601:surgery; D008297:Male; D008875:Middle Aged; D012907:Smoking / Q000009:adverse effects; D003074:Solitary Pulmonary Nodule / Q000175:diagnosis* / Q000556:secondary / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000473:pathology