title: [A curative report of multiple organ dysfunction syndrome and disseminated intravascular coagulation due to methicillin-resistant Staphylococcus aureus caused mediastinitis after cardiac surgery].
abstract: We experienced a curative case, who was a fifty nine-year old man suffered from multiple organ dysfunction syndrome (MODS) and disseminated intravascular coagulation (DIC) due to Methicillin-resistant Staphylococcus aureus (MRSA) caused-mediastinitis following cardiac surgery against atrial septal defect (ASD) and tricuspid regurgitation. We successfully treated him with mediastinal irrigations by a large quantities of physiological saline containing 1% Povidone iodine (PI) and MRSA sensitive antibiotics as well as artificial supports such as plasma pheresis and hemodialysis against failure organs. It may be due to the prompt treatment with mediastinal irrigation and well timed dosage of sensitive antibiotics against the origin of sepsis that such a serious patient like this case could be recovered from MODS and DIC. In addition, it may be very effective to irrigate with 1% PI against MRSA-caused-mediastinitis.
authors.affiliation: First Department of Stogery, Shimane Medical University, Izumo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Gu
authors.forename: K
authors.initials: K
authors.lastname: Nakayama
authors.forename: Y
authors.initials: Y
authors.lastname: Saitoh
authors.forename: S
authors.initials: S
authors.lastname: Nosaka
authors.forename: T
authors.initials: T
authors.lastname: Ooishi
authors.forename: T
authors.initials: T
authors.lastname: Sasaki
authors.forename: M
authors.initials: M
authors.lastname: Yamauchi
mesh_terms: D006348:Cardiac Surgical Procedures; D004211:Disseminated Intravascular Coagulation / Q000209:etiology* / Q000628:therapy; D006344:Heart Septal Defects, Atrial / Q000601:surgery; D006801:Humans; D008297:Male; D008480:Mediastinitis / Q000382:microbiology* / Q000628:therapy*; D016106:Methicillin Resistance; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology* / Q000628:therapy; D011183:Postoperative Complications / Q000628:therapy*; D013203:Staphylococcal Infections; D013211:Staphylococcus aureus; D018746:Systemic Inflammatory Response Syndrome / Q000209:etiology; D007507:Therapeutic Irrigation; D014262:Tricuspid Valve Insufficiency / Q000601:surgery