title: Polymorphisms in drug-metabolizing enzymes: what is their clinical relevance and why do they exist?
authors.forename: D W
authors.initials: DW
authors.lastname: Nebert
mesh_terms: D000107:Acetylation; D000818:Animals; D001191:Arylamine N-Acetyltransferase / Q000235:genetics* / Q000378:metabolism; D001675:Bioethics; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics* / Q000378:metabolism; D003647:Debrisoquin / Q000378:metabolism; D004032:Diet; D004198:Disease Susceptibility; D005006:Ethnicity; D005954:Glucosephosphate Dehydrogenase / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D009369:Neoplasms / Q000235:genetics; D010084:Oxidation-Reduction; D011110:Polymorphism, Genetic
chemical_list: D005954:Glucosephosphate Dehydrogenase; D019389:Cytochrome P-450 CYP2D6; D001191:Arylamine N-Acetyltransferase; D003647:Debrisoquin