title: Treatment of severe thallium intoxication.
abstract: We report a successfully treated case of severe thallium intoxication. In spite of very high serum thallium (5,240 micrograms/L), symptomatology was minor and recovery complete. Prussian Blue was administered, diuresis was enhanced by intravenous fluids and a prolonged hemodialysis was started early. High blood flows (300 mL/min) and intravenous potassium chloride supplements, to mobilize thallium from the tissues, resulted in good clearances (96 to 150 mL/min). In order to prevent the well known complications, we recommend aggressive treatment of severe thallium intoxication.
authors.affiliation: Department of Nephrology-Hypertension, A.Z. Stuivenberg Antwerpen, Belgium.
authors.forename: M L
authors.initials: ML
authors.lastname: Malbrain
authors.forename: G L
authors.initials: GL
authors.lastname: Lambrecht
authors.forename: E
authors.initials: E
authors.lastname: Zandijk
authors.forename: P A
authors.initials: PA
authors.lastname: Demedts
authors.forename: H M
authors.initials: HM
authors.lastname: Neels
authors.forename: W
authors.initials: W
authors.lastname: Lambert
authors.forename: A P
authors.initials: AP
authors.lastname: De Leenheer
authors.forename: R L
authors.initials: RL
authors.lastname: Lins
authors.forename: R
authors.initials: R
authors.lastname: Daelemans
mesh_terms: D000328:Adult; D000931:Antidotes / Q000627:therapeutic use*; D005260:Female; D005295:Ferrocyanides / Q000627:therapeutic use*; D005751:Gastric Lavage; D006801:Humans; D011041:Poisoning / Q000628:therapy*; D011189:Potassium Chloride / Q000008:administration & dosage; D006435:Renal Dialysis; D013406:Suicide, Attempted; D013793:Thallium / Q000097:blood / Q000506:poisoning* / Q000652:urine
chemical_list: D000931:Antidotes; D005295:Ferrocyanides; D011189:Potassium Chloride; D013793:Thallium; C000170:ferric ferrocyanide