Anti-inflammatory and antiulcer activity of Teucrium buxifolium.
Teucrium buxifolium Spanish endemic, have traditionally been used for the treatment of rheumatic and other inflammatory affections. In this work, phytochemical screening was carried out to ascertain the qualitative composition of this species and we have studied the anti-inflammatory and antiulcer activity of Teucrium buxifolium. This species has exhibited potent anti-inflammatory properties against experimentally-induced arthritis and carrageenin paw edema. Additionally, Teucrium buxifolium species have displayed significant antiulcer and cytoprotective activity.
Fernández Puntero
B
B
Departamento de Farmacología, Facultad de Farmacia, Universidad Complutense de Madrid, Ciudad Universitaria, Spain.
Iglesias Peinado
I
I
Villar del Fresno
A M
AM
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use* / Q000633:toxicity; D000897:Anti-Ulcer Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D001169:Arthritis, Experimental / Q000188:drug therapy*; D002351:Carrageenan / Q000008:administration & dosage / Q000633:toxicity; D004195:Disease Models, Animal; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy*; D005260:Female; D005753:Gastric Mucosa / Q000166:cytology / Q000187:drug effects; D007213:Indomethacin / Q000008:administration & dosage / Q000633:toxicity; D051379:Mice; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar; D013030:Spain; D013276:Stomach Ulcer / Q000139:chemically induced / Q000517:prevention & control*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000897:Anti-Ulcer Agents; D010936:Plant Extracts; D002351:Carrageenan; D007213:Indomethacin