title: [Contribution of free-radical reactions of chamber humor to the development of primary open-angle glaucoma].
abstract: The level of lipid peroxidation products (malonic dialdehyde) is more than two times increased in the anterior chamber humor in patients with far advanced glaucoma in comparison with the well-developed stage. The level of the total antioxidant activity of humor is reliably lowered. A correlation has been revealed between the antioxidant activity of humor and its production. These results prompt us to recommend antioxidants for therapy of primary glaucoma.
authors.affiliation: State Medical Academy, Ivanovo.
authors.forename: N I
authors.initials: NI
authors.lastname: Kurysheva
authors.forename: M I
authors.initials: MI
authors.lastname: Vinetskaia
authors.forename: V P
authors.initials: VP
authors.lastname: Erichev
authors.forename: M L
authors.initials: ML
authors.lastname: Demchuk
authors.forename: S I
authors.initials: SI
authors.lastname: Kuryshev
mesh_terms: D000368:Aged; D000869:Anterior Eye Segment; D000975:Antioxidants / Q000378:metabolism; D001082:Aqueous Humor / Q000378:metabolism*; D005260:Female; D005609:Free Radicals / Q000378:metabolism; D005902:Glaucoma, Open-Angle / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D015227:Lipid Peroxidation / Q000502:physiology*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism*; D008875:Middle Aged
chemical_list: D000975:Antioxidants; D005609:Free Radicals; D008315:Malondialdehyde