title: Are the reactive oxygen-derived species (ROS) interactive properties of the many therapeutic drugs from various categories pertinent to their beneficial effects?
abstract: Many pathologic states are known to involve the generation of reactive oxygen species, (ROS). It is not known at present to what extent these phenomena are due to ROS formation, or if their formation is a result of the disease. Many therapeutic drugs either scavenge ROS or inhibit their formation. The purpose of this review is to match the drugs used for certain diseases with their anti-ROS actions. This attempted correlation is made to try to give an answer to the title question.
authors.affiliation: Centre de Neurochimie, Strasbourg, France.
authors.forename: C D
authors.initials: CD
authors.lastname: Cash
mesh_terms: D018681:Anesthetics, General / Q000627:therapeutic use; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000627:therapeutic use; D000978:Antiparkinson Agents / Q000627:therapeutic use; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000188:drug therapy / Q000503:physiopathology; D002490:Central Nervous System / Q000503:physiopathology; D016166:Free Radical Scavengers / Q000627:therapeutic use*; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy / Q000503:physiopathology; D017382:Reactive Oxygen Species / Q000502:physiology*; D014665:Vasodilator Agents / Q000627:therapeutic use
chemical_list: D018681:Anesthetics, General; D000889:Anti-Arrhythmia Agents; D000893:Anti-Inflammatory Agents; D000959:Antihypertensive Agents; D000978:Antiparkinson Agents; D002121:Calcium Channel Blockers; D016166:Free Radical Scavengers; D017382:Reactive Oxygen Species; D014665:Vasodilator Agents