[Difference in costs of autologous transplantation of peripheral and bone marrow hematopoietic stem cells. A retrospective analysis over 1 year of transplantation in lymphoma, Hodgkin's disease and myeloma in a Center].
The study analysed the financial benefits of transplantation with peripheral blood stem-cells primed after chemotherapy and growth factor in comparison with bone marrow transplantation. Twenty-three consecutive transplantations were performed during one year: 14 peripheral blood stem-cell (CSC group) and 9 bone marrow transplantations (MO group). No differences in patients characteristics were seen between the two groups except for higher number of "BEAM" conditioning in CSC group. Were analyzed delay in neutrophil and platelet recovery, numbers of days in hospital, with fever, under antibiotics, costs of supportive therapy, stem-cell collection and cryopreservation. Difference was significant for duration of neutropenia with advantages in CSC group, but the number on days in hospital, with fever or under antibiotics were similar. Number of platelet transfusions was reduced in CFC group: this economical advantage was lost with the cost of growth factor used for priming stem-cells stem-cell collections and cryopreservations. In our retrospective study, financial advantages associated to peripheral blood stem-cell transplantation was not verified.
Rio
B
B
Service d'Hématologie et Service d'Hémobiologie, Hôtel-Dieu, Paris.
Marjanovic
Z
Z
Belhocine
R
R
Vekhoff
A
A
Andrieu
V
V
Klaren
J
J
Boccaccio
C
C
Delmer
A
A
Ajchenbaum-Cymbalista
F
F
Hunault
M
M
Bazarbachi
A
A
Lévy
V
V
Andreu
G
G
Zittoun
R
R
D000293:Adolescent; D000328:Adult; D016026:Bone Marrow Transplantation / Q000191:economics*; D003365:Costs and Cost Analysis; D018380:Hematopoietic Stem Cell Transplantation / Q000191:economics*; D006689:Hodgkin Disease / Q000601:surgery*; D006801:Humans; D007902:Length of Stay / Q000191:economics; D008223:Lymphoma / Q000601:surgery*; D008875:Middle Aged; D009101:Multiple Myeloma / Q000601:surgery*; D011788:Quality of Life; D012189:Retrospective Studies; D014182:Transplantation, Autologous