title: Developing treatment guidelines for Alzheimer's disease and other dementias.
abstract: Developing treatment guidelines for Alzheimer's disease and other dementias depends primarily on a literature review. A recent review suggests that tacrine is modestly effective in treating cognitive symptoms and that-neuroleptic drugs are modestly effective in treating agitation and aggression. Few randomized, double-blind, placebo-controlled trials of other agents used for the treatment of cognitive and noncognitive symptoms of dementia have been performed. A variety of behavioral/environmental interventions show modest but nonspecific effects in treating Alzheimer's disease and other types of dementia. Family-focused support interventions are moderately effective and may delay nursing home placement.
authors.affiliation: Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, Md 21287-7279, USA.
authors.forename: P V
authors.initials: PV
authors.lastname: Rabins
mesh_terms: D000544:Alzheimer Disease / Q000188:drug therapy / Q000523:psychology / Q000628:therapy*; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001521:Behavior Therapy; D003072:Cognition Disorders / Q000188:drug therapy / Q000628:therapy; D003704:Dementia / Q000188:drug therapy / Q000628:therapy*; D006801:Humans; D015201:Meta-Analysis as Topic; D017410:Practice Guidelines as Topic / Q000592:standards*; D013619:Tacrine / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents; D013619:Tacrine