title: The SBASE protein domain library, release 5.0: a collection of annotated protein sequence segments.
abstract: SBASE 5.0 is the fifth release of SBASE, a collection of annotated protein domain sequences that represent various structural, functional, ligand-binding and topogenic segments of proteins. SBASE was designed to facilitate the detection of functional homologies and can be searched with standard database-search programs. The present release contains over 79863 entries provided with standardized names and is cross-referenced to all major sequence databases and sequence pattern collections. The information is assigned to individual domains rather than to entire protein sequences, thus SBASE contains substantially more cross-references and links than do the protein sequence databases. The entries are clustered into >16 000 groups in order to facilitate the detection of distant similarities. SBASE 5.0 is freely available by anonymous 'ftp' file transfer from <ftp.icgeb.trieste.it >. Automated searching of SBASE with BLAST can be carried out with the WWW-server <http://www.icgeb.trieste.it/sbase/ >. and with the electronic mail server <sbase@icgeb.trieste.it >which now also provides a graphic representation of the homologies. A related WWW-server <http://www.abc.hu/blast.html > and e-mail server <domain@hubi.abc.hu > predicts SBASE domain homologies on the basis of SWISS-PROT searches.
authors.affiliation: ABC Institute for Biochemistry and Protein Research, 2100 Gödöllö, Hungary.
authors.forename: P
authors.initials: P
authors.lastname: Fábián
authors.forename: J
authors.initials: J
authors.lastname: Murvai
authors.forename: Z
authors.initials: Z
authors.lastname: Hátsági
authors.forename: K
authors.initials: K
authors.lastname: Vlahovicek
authors.forename: H
authors.initials: H
authors.lastname: Hegyi
authors.forename: S
authors.initials: S
authors.lastname: Pongor
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D016208:Databases, Factual; D006801:Humans; D008969:Molecular Sequence Data; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry*; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
chemical_list: D011506:Proteins