title: Influence of uvulopalatopharyngoplasty on alpha-EEG arousals in nonapnoeic snorers.
abstract: Arousals are more numerous in heavy snorers than in nonsnorers and might be a cause of excessive daytime sleepiness (EDS) in these patients. The present study investigated whether treatment of snoring by uvulopalatopharyngoplasty (UPPP) had an influence on sleep microstructure in nonapnoeic snorers. The polysomnographic records of 10 nonapnoeic snorers were reviewed retrospectively and arousals scored according to the American Sleep Disorders Association (ASDA) 3 s definition. Scores for snoring, EDS and polysomnographic data were compared before and after UPPP (mean (+/-SD) time interval 249 +/- 183 days). UPPP resulted in a subjective improvement of snoring and a significant decrease in the arousal index (mean 14.6, 95% confidence interval (95% CI) 8.5-20.8 vs mean 9.1, 95% CI 6.6-11.5) (p = 0.01). EDS and the amount of slow-wave sleep remained unchanged. Uvulopalatopharyngoplasty resulted in an improvement of subjective snoring and a significant decrease of arousals in nonapnoeic snorers. Although these data do not provide any insight into whether the improvement observed can be maintained on a long-term basis, uvulopalatopharyngoplasty can be considered as a useful treatment modality to reduce sleep fragmentation and snoring in nonapnoeic snorers.
authors.affiliation: Dept of Otorhinolaryngology, Antwerp University, UIA, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: Boudewyns
authors.forename: W
authors.initials: W
authors.lastname: De Cock
authors.forename: M
authors.initials: M
authors.lastname: Willemen
authors.forename: M
authors.initials: M
authors.lastname: Wagemans
authors.forename: W
authors.initials: W
authors.lastname: De Backer
authors.forename: P H
authors.initials: PH
authors.lastname: Van de Heyning
mesh_terms: D000328:Adult; D000513:Alpha Rhythm; D001049:Apnea; D001143:Arousal / Q000502:physiology*; D002245:Carbon Dioxide / Q000097:blood; D016001:Confidence Intervals; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010159:Palate / Q000601:surgery*; D010614:Pharynx / Q000601:surgery*; D017286:Polysomnography; D012189:Retrospective Studies; D012890:Sleep / Q000502:physiology; D012894:Sleep Stages / Q000502:physiology; D012913:Snoring / Q000503:physiopathology / Q000601:surgery*; D014609:Uvula / Q000601:surgery*
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen