title: [The effect of calcium channel blockers on the effects of ethanol in the immobilization of mice].
abstract: A model of the depressive behavior was used to study the action of the calcium channel blockers combined with ethanol. The ethanol dose used (2 g/kg, per os) caused behavioral changes by the depressive type. From two drugs fendilin (20 mg/kg) and nifedipine (10 mg/kg) showing the antidepressive activity in the test the ethanol effect was counteracted only by the nifedipine. Other drugs, such as cinnarizine (50 mg/kg), verapamil (25 mg/kg), flunarizine, and sabeluzol (10 mg/kg), did not produce a significant effect.
authors.forename: V L
authors.initials: VL
authors.lastname: Kozlovskiĭ
authors.forename: I V
authors.initials: IV
authors.lastname: Prakh'e
mesh_terms: D000818:Animals; D002121:Calcium Channel Blockers / Q000494:pharmacology*; D004347:Drug Interactions; D000431:Ethanol / Q000494:pharmacology*; D051379:Mice; D008810:Mice, Inbred C57BL; D009043:Motor Activity / Q000187:drug effects; D012149:Restraint, Physical; D013623:Tail; D013997:Time Factors
chemical_list: D002121:Calcium Channel Blockers; D000431:Ethanol