[Contribution of free-radical reactions of chamber humor to the development of primary open-angle glaucoma].
The level of lipid peroxidation products (malonic dialdehyde) is more than two times increased in the anterior chamber humor in patients with far advanced glaucoma in comparison with the well-developed stage. The level of the total antioxidant activity of humor is reliably lowered. A correlation has been revealed between the antioxidant activity of humor and its production. These results prompt us to recommend antioxidants for therapy of primary glaucoma.
Kurysheva
N I
NI
State Medical Academy, Ivanovo.
Vinetskaia
M I
MI
Erichev
V P
VP
Demchuk
M L
ML
Kuryshev
S I
SI
D000368:Aged; D000869:Anterior Eye Segment; D000975:Antioxidants / Q000378:metabolism; D001082:Aqueous Humor / Q000378:metabolism*; D005260:Female; D005609:Free Radicals / Q000378:metabolism; D005902:Glaucoma, Open-Angle / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D015227:Lipid Peroxidation / Q000502:physiology*; D008297:Male; D008315:Malondialdehyde / Q000378:metabolism*; D008875:Middle Aged
D000975:Antioxidants; D005609:Free Radicals; D008315:Malondialdehyde