title: Adenosquamous carcinoma of the facial bones, skull base, and calvaria: CT and MR manifestations.
abstract: A 62-year-old woman had proptosis of the right eye, decreased visual acuity of the left eye, and no other focal neurologic deficits. She had a grand mal seizure 1 month before admission. The CT and MR studies showed extensive bone destruction of the margins of the right orbit, the floor of the middle cranial fossa, the right cavernous sinus, and much of the calvaria. There was considerable dural disease and tumor in the right orbit, paranasal sinuses, and scalp, as well as mucoceles of the left ethmoidal sinus with desiccated secretions. The diagnosis was adenosquamous carcinoma, an aggressive tumor related to both squamous cell carcinoma and adenocarcinoma.
authors.affiliation: Department of Radiology, Mount Sinai School of Medicine, City University of New York, NY, USA.
authors.forename: P M
authors.initials: PM
authors.lastname: Som
authors.forename: A R
authors.initials: AR
authors.lastname: Silvers
authors.forename: P J
authors.initials: PJ
authors.lastname: Catalano
authors.forename: M
authors.initials: M
authors.lastname: Brandwein
authors.forename: A S
authors.initials: AS
authors.lastname: Khorsandi
mesh_terms: D001706:Biopsy; D018196:Carcinoma, Adenosquamous / Q000175:diagnosis*; D002426:Cavernous Sinus / Q000473:pathology; D004388:Dura Mater / Q000473:pathology; D005147:Facial Bones / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009078:Mucocele / Q000175:diagnosis; D009915:Orbit / Q000473:pathology; D009918:Orbital Neoplasms / Q000175:diagnosis; D010255:Paranasal Sinus Neoplasms / Q000175:diagnosis; D010256:Paranasal Sinuses / Q000473:pathology; D012535:Scalp / Q000473:pathology; D012886:Skull / Q000473:pathology; D019292:Skull Base Neoplasms / Q000175:diagnosis*; D012888:Skull Neoplasms / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed