title: Effects of a pH 7.4, lactate-based and a pH 7.4, bicarbonate-based peritoneal dialysis solutions on neutrophil superoxide generation.
abstract: Neutrophil superoxide formation was similar when cells were incubated in self-made, non-autoclaved pH 7.4, lactate-based peritoneal dialysis solutions or in their self-made, non-autoclaved, pH 7.4, bicarbonate-based counterparts. On the other hand, commercially available, autoclaved, pH 7.4, lactate-based peritoneal dialysis solutions resulted in inhibition of superoxide production when compared to their self-made, non-autoclaved, pH 7.4, lactate-based or bicarbonate-based counterparts. The cause for this inhibition of superoxide generation is at present unknown.
authors.affiliation: Department of Medicine, Loyola University Chicago, Stritch School of Medicine, Maywood, USA.
authors.forename: T S
authors.initials: TS
authors.lastname: Ing
authors.forename: B P
authors.initials: BP
authors.lastname: Patel
authors.forename: J A
authors.initials: JA
authors.lastname: Patel
authors.forename: N K
authors.initials: NK
authors.lastname: Patel
authors.forename: A W
authors.initials: AW
authors.lastname: Yu
authors.forename: A
authors.initials: A
authors.lastname: Osman
authors.forename: F Q
authors.initials: FQ
authors.lastname: Zhou
mesh_terms: D000328:Adult; D001639:Bicarbonates / Q000494:pharmacology*; D015314:Dialysis Solutions / Q000592:standards*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007773:Lactates / Q000494:pharmacology*; D008297:Male; D009504:Neutrophils / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D010530:Peritoneal Dialysis; D013242:Sterilization; D013481:Superoxides / Q000378:metabolism*
chemical_list: D001639:Bicarbonates; D015314:Dialysis Solutions; D007773:Lactates; D013481:Superoxides