Induction of immediate early response genes by hypoxia. Possible molecular bases for systems adaptation to low pO2.
Cherniack
N S
NS
Case Western Reserve University, Cleveland, Ohio, USA.
Shenoy
P C
PC
Mishra
R
R
Simonson
M
M
Prabhakar
N R
NR
D000222:Adaptation, Physiological / Q000235:genetics; D000818:Animals; D015687:Cell Hypoxia / Q000235:genetics; D004298:Dopamine / Q000378:metabolism; D004790:Enzyme Induction; D005347:Fibroblasts / Q000378:metabolism; D005786:Gene Expression Regulation; D015972:Gene Expression Regulation, Neoplastic; D017781:Genes, Immediate-Early; D016762:Genes, fos; D016758:Genes, jun; D000860:Hypoxia / Q000235:genetics* / Q000378:metabolism; D017874:Immediate-Early Proteins / Q000096:biosynthesis; D009363:Neoplasm Proteins / Q000096:biosynthesis / Q000235:genetics; D009447:Neuroblastoma / Q000473:pathology; D016716:PC12 Cells / Q000378:metabolism; D016760:Proto-Oncogene Proteins c-fos / Q000096:biosynthesis; D016755:Proto-Oncogene Proteins c-jun / Q000096:biosynthesis; D051381:Rats; D014407:Tumor Cells, Cultured; D014446:Tyrosine 3-Monooxygenase / Q000096:biosynthesis / Q000235:genetics
D017874:Immediate-Early Proteins; D009363:Neoplasm Proteins; D016760:Proto-Oncogene Proteins c-fos; D016755:Proto-Oncogene Proteins c-jun; D014446:Tyrosine 3-Monooxygenase; D004298:Dopamine