title: European Gene Mapping Project (EUROGEM): breakpoint panels for human chromosomes based on the CEPH reference families. Centre d'Etude du Polymorphisme Humain.
abstract: Meiotic breakpoint panels for human chromosomes 2, 3, 4, 5, 6, 7, 8, 9, 10, 13, 14, 15, 17, 18, 20 and X were constructed from genotypes from the CEPH reference families. Each recombinant chromosome included has a breakpoint well-supported with reference to defined quantitative criteria. The panels were constructed at both a low-resolution, useful for a first-pass localization, and high-resolution, for a more precise placement. The availability of such panels will reduce the number of genotyping experiments necessary to order new polymorphisms with respect to existing genetic markers. This paper shows only a representative sample of the breakpoints detected. The complete data are available on the World Wide Web (URL http:/(/)www.icnet.uk/axp/hgr/eurogem++ +/HTML/data.html) or by anonymous ftp (ftp.gene.ucl.ac.uk in/pub/eurogem/maps/breakpoints).
authors.affiliation: Human Genetic Resources Laboratory, Imperial Cancer Research Fund. Potters Bar, Herts, UK.
authors.forename: S A
authors.initials: SA
authors.lastname: Cox
authors.forename: J
authors.initials: J
authors.lastname: Attwood
authors.forename: S P
authors.initials: SP
authors.lastname: Bryant
authors.forename: R
authors.initials: R
authors.lastname: Bains
authors.forename: S
authors.initials: S
authors.lastname: Povey
authors.forename: M
authors.initials: M
authors.lastname: Rebello
authors.forename: M
authors.initials: M
authors.lastname: Kapsetaki
authors.forename: N K
authors.initials: NK
authors.lastname: Moschonas
authors.forename: K H
authors.initials: KH
authors.lastname: Grzeschik
authors.forename: M
authors.initials: M
authors.lastname: Otto
authors.forename: M
authors.initials: M
authors.lastname: Dixon
authors.forename: H E
authors.initials: HE
authors.lastname: Sudworth
authors.forename: R F
authors.initials: RF
authors.lastname: Kooy
authors.forename: A
authors.initials: A
authors.lastname: Wright
authors.forename: P
authors.initials: P
authors.lastname: Teague
authors.forename: L
authors.initials: L
authors.lastname: Terrenato
authors.forename: G
authors.initials: G
authors.lastname: Vergnaud
authors.forename: S
authors.initials: S
authors.lastname: Monfouilloux
authors.forename: J
authors.initials: J
authors.lastname: Weissenbach
authors.forename: O
authors.initials: O
authors.lastname: Alibert
authors.forename: C
authors.initials: C
authors.lastname: Dib
authors.forename: S
authors.initials: S
authors.lastname: Fauré
authors.forename: E
authors.initials: E
authors.lastname: Bakker
authors.forename: N M
authors.initials: NM
authors.lastname: Pearson
authors.forename: N K
authors.initials: NK
authors.lastname: Spurr
mesh_terms: D002874:Chromosome Mapping; D002877:Chromosomes, Human; D005060:Europe; D005838:Genotype; D016045:Human Genome Project; D006801:Humans; D008540:Meiosis / Q000235:genetics