Progress in an oral vaccine for amebiasis. Expression of the serine rich Entamoeba histolytica protein (SREHP) in the avirulent vaccine strain Salmonella typhi TY2 chi 4297 (delta cya delta crp delta asd): safety and immunogenicity in mice.
Zhang
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Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.
Stanley
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SL
D000284:Administration, Oral; D000562:Amebiasis / Q000517:prevention & control*; D000818:Animals; D001428:Bacterial Vaccines / Q000276:immunology*; D008565:Membrane Proteins / Q000096:biosynthesis / Q000235:genetics*; D051379:Mice; D008807:Mice, Inbred BALB C; D015800:Protozoan Proteins / Q000096:biosynthesis / Q000235:genetics*; D016052:Protozoan Vaccines / Q000009:adverse effects* / Q000276:immunology; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis; D012485:Salmonella typhi / Q000472:pathogenicity; D014613:Vaccines, Attenuated / Q000276:immunology*; D014774:Virulence
D001428:Bacterial Vaccines; D008565:Membrane Proteins; D015800:Protozoan Proteins; D016052:Protozoan Vaccines; D011993:Recombinant Fusion Proteins; D014613:Vaccines, Attenuated; C073020:serine-rich protein, Entamoeba histolytica