title: A computer controlled pulsatile pump: preliminary study.
abstract: A Stepper Motor Driven Reciprocating Pump (SDRP) can replace roller pumps and rotary pumps for cardio pulmonary bypass, hemodialysis and regional perfusion. The blood pumping ventricles are basically the same as ventricles used for air driven artificial hearts and ventricular assist devices. The electric stepper motor uses a flexible linkage belt to produce a reciprocating movement, which pushes a hard sphere into the diaphragm of the blood ventricles. The SDRP generates pulsatile flow and has a small priming volume. The preset power level of the motor driver limits the maximum potential outflow pressure, so the driver acts as a safety device. A double pump can be made by connecting two fluid pumping chambers to opposing sides of the motor base. Each pump generates pulsatile flow. Pressure and flow studies with water were undertaken. Preliminary blood studies showed low hemolysis, even when circulating a small amount of blood up to 16 hours.
authors.affiliation: Kolff's Laboratory, Department of Bioengineering, University of Utah, Salt Lake City, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Zwarts
authors.forename: S R
authors.initials: SR
authors.lastname: Topaz
authors.forename: D N
authors.initials: DN
authors.lastname: Jones
authors.forename: W J
authors.initials: WJ
authors.lastname: Kolff
mesh_terms: D000818:Animals; D002417:Cattle; D006353:Heart-Assist Devices / Q000592:standards*; D006454:Hemoglobins / Q000032:analysis; D006461:Hemolysis; D066298:In Vitro Techniques; D011673:Pulsatile Flow; D013056:Spectrophotometry, Ultraviolet; D013318:Stroke Volume; D013813:Therapy, Computer-Assisted
chemical_list: D006454:Hemoglobins