Alanine EPR dosimeter response in proton therapy beams.
We report a series of measurements directed to assess the suitability of alanine as a mailable dosimeter for dosimetry quality assurance of proton radiation therapy beams. These measurements include dose-response of alanine at 140 MeV, and comparison of response vs energy with a parallel plate ionization chamber. All irradiations were made at the Harvard Cyclotron Laboratory, and the dosimeters were read at NIST. The results encourage us that alanine could be expected to serve as a mailable dosimeter with systematic error due to differential energy response no greater than 3% when doses of 25 Gy are used.
Gall
K
K
Massachusetts General Hospital, Department of Radiation Oncology, Boston 02114, USA.
Desrosiers
M
M
Bensen
D
D
Serago
C
C
D000409:Alanine / Q000737:chemistry / Q000528:radiation effects*; D004307:Dose-Response Relationship, Radiation; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods* / Q000592:standards / Q000706:statistics & numerical data; D005069:Evaluation Studies as Topic; D005609:Free Radicals / Q000032:analysis / Q000528:radiation effects; D006801:Humans; D061766:Proton Therapy; D011874:Radiometry / Q000295:instrumentation / Q000379:methods* / Q000592:standards; D011879:Radiotherapy Dosage / Q000592:standards; D011882:Radiotherapy, High-Energy
D005609:Free Radicals; D000409:Alanine