title: [Electrosurgical loop excision of the transformation zone in treatment of cervix neoplasia].
abstract: 100 patients with CIN on referral Pap and with a distinct cervical lesion on colposcopy were treated with the loop electrosurgical excisional procedure (LEEP). Compared with 60 women who underwent cold-knife conization, the number of lesions classified as CIN-3 or more did not differ between the two groups (53% vs 53.3%). Severe haemorrhage and cervical stenosis were only observed after conization. Involvement of resection margins was found in 18% of all LEEP and in 16.7% of all cone biopsies. 3-12 months after LEEP the rate of cytologically and biopsy proven neoplasia was 2.2%. LEEP is a safe and effective procedure and should be used as the treatment of choice for distinct cervical lesions.
authors.affiliation: Abt. für spezielle Onkologie, Frauenklinik, Medizinische Hochschule Hannover.
authors.forename: K U
authors.initials: KU
authors.lastname: Petry
authors.forename: M
authors.initials: M
authors.lastname: Glaubitz
authors.forename: H
authors.initials: H
authors.lastname: Maschek
authors.forename: G
authors.initials: G
authors.lastname: Böhmer
authors.forename: G
authors.initials: G
authors.lastname: Linge
authors.forename: H
authors.initials: H
authors.lastname: Kühnle
mesh_terms: D001706:Biopsy; D019092:Conization / Q000295:instrumentation; D004564:Electrocoagulation / Q000295:instrumentation*; D004867:Equipment Design; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000473:pathology / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology / Q000473:pathology; D014412:Tumor Virus Infections / Q000473:pathology / Q000601:surgery; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*; D014626:Vaginal Smears; D014945:Wound Healing / Q000502:physiology; D002578:Uterine Cervical Dysplasia / Q000473:pathology / Q000601:surgery*