Gamma Knife treatment of 100 consecutive meningiomas.
Clinical and imaging results of Gamma Knife treatment of 100 consecutive patients with intracranial meningiomas are reported. Only 1 patient refused follow-up imaging and her symptoms remain improved after 1 year. Mean values for the patient and treatment parameters were age 61 years, duration of symptoms 3.6 years, time since diagnosis 3 years, average tumor diameter 2.4 cm, surface radiation dose 15 Gy and number of isocenters 5. Clinical outcomes revealed that 6 were improved, 75 were unchanged and 17 had deteriorated. Of the latter, 8 were operated, 4 were treated medically and 5 died. Imaging follow-up showed no growth in 87 patients. The size of tumors treated ranged from 0.66 to 6.8 cm average diameter. In the 77 patients with tumors with an average diameter of 3 cm or less, only 2 (3%) showed further growth, and none died of tumor-related causes.
Hudgins
W R
WR
Department of Neurosurgery, Presbyterian Hospital of Dallas, Tex., USA.
Barker
J L
JL
Schwartz
D E
DE
Nichols
T D
TD
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005500:Follow-Up Studies; D006801:Humans; D016014:Linear Models; D008577:Meningeal Neoplasms / Q000601:surgery*; D008579:Meningioma / Q000601:surgery*; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D016634:Radiosurgery