title: Some additional results about polymorphisms in models of an additive quantitative trait under stabilizing selection.
abstract: The existence of two stable, symmetric (allelic frequency 0.5 in each locus) polymorphic states is demonstrated for a two-locus model of an additive quantitative trait under strong Gaussian selection. Linkage disequilibrium at one of the states is negative whereas it is positive at the other state. For a three-locus model, it is shown that in order to maintain a stable polymorphism in all three loci, selection must be sufficiently but not excessively strong relative to recombination. Also, positive linkage disequilibrium can be maintained in a three-locus model under stabilizing selection that is not very strong.
authors.affiliation: Department of Ecology and Evolution, University of Chicago, IL 60637-1573, USA. sashu@pondside.uchicago.edu
authors.forename: A
authors.initials: A
authors.lastname: Gimelfarb
mesh_terms: D000483:Alleles; D000818:Animals; D005787:Gene Frequency; D015810:Linkage Disequilibrium; D008433:Mathematics; D008957:Models, Genetic; D011110:Polymorphism, Genetic; D012641:Selection, Genetic