title: Renal ultrasonic findings in sulphadiazine-induced renal failure.
abstract: The increased incidence of cerebral toxoplasmosis in AIDS has led to a resurgence in the use of sulphadiazine. One complication of this is acute renal failure secondary to sulphadiazine-induced crystalluria. Three cases are described which demonstrate a spectrum of ultrasound findings ranging from echogenic foci in the renal parenchyma to echogenic material in both dilated and non-dilated collecting systems. In patients with AIDS having sulphadiazine treatment, these ultrasonic findings suggest that sulphadiazine is the cause of the renal failure.
authors.affiliation: Department of Genito-Urinary Medicine, St James's Hospital, Dublin 8, Ireland.
authors.forename: D
authors.initials: D
authors.lastname: Kane
authors.forename: J M
authors.initials: JM
authors.lastname: Murphy
authors.forename: S
authors.initials: S
authors.lastname: Keating
authors.forename: G F
authors.initials: GF
authors.lastname: Wilson
authors.forename: F M
authors.initials: FM
authors.lastname: Mulcahy
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy*; D058186:Acute Kidney Injury / Q000139:chemically induced / Q000000981:diagnostic imaging; D000328:Adult; D003460:Crystallization; D006801:Humans; D008297:Male; D008875:Middle Aged; D013411:Sulfadiazine / Q000009:adverse effects*; D016781:Toxoplasmosis, Cerebral / Q000150:complications / Q000188:drug therapy*; D014463:Ultrasonography; D014570:Urologic Diseases / Q000139:chemically induced* / Q000000981:diagnostic imaging*
chemical_list: D013411:Sulfadiazine