Pregnancy-induced elevation in aortic vascular smooth muscle actin in the Sprague-Dawley rat.
A component of hemodynamic responses during pregnancy may include structural changes in the arterial tree. Smooth muscle alpha-actin is a major structural-contractile protein of muscle cells. We observed a marked increase. In expression of actin during pregnancy in the rat aorta, suggesting a structural alteration of conduit arteries.
Davidge
S T
ST
Department of Obstetrics, Gynecology, and Reproductive Sciences, Magee-Womens Research Institute, University of Pittsburgh, PA 15213, USA.
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L
L
Lessard
J L
JL
McLaughlin
M K
MK
D000199:Actins / Q000096:biosynthesis*; D000818:Animals; D001011:Aorta / Q000378:metabolism*; D005260:Female; D009131:Muscle, Smooth, Vascular / Q000378:metabolism*; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley
D000199:Actins