title: Effect of previous sclerotherapy on the outcome of gastro-oesophageal devascularization and oesophageal transection in bleeding oesophageal varices.
abstract: This retrospective analysis studied the effect of sclerotherapy on subsequent oesophageal transection in the management of patients with bleeding oesophageal varices and compared the result with that in those who did not receive sclerotherapy as the primary treatment. Fifty patients were treated by gastro-oesophageal devascularization and oesophageal transection for bleeding oesophageal varices over a 4-year period. Twenty-six patients did not receive sclerotherapy (group 1) and 24 received between one and four sessions of sclerotherapy (group 2) before surgery. Oedema and thickness of the lower end of the oesophagus and some adhesions were noted during surgery in patients who had had previous sclerotherapy; however, stapled oesophageal transection and anastomosis could be performed in all these patients. There was no oesophageal leak in any patient, although there was a higher rate of chest complications (nine versus six patients) in group 2. Six patients (12 per cent) died (three in each group) during the postoperative period; three had Child grade C disease. It is concluded that the decision to operate to control bleeding varices should be made early. One or two sessions of sclerotherapy before surgery does not increase intraoperative difficulty or the postoperative leak rate following oesophageal transection. The outcome of surgery is directly related to the state of liver reserve (Child grade).
authors.affiliation: Department of Surgery, College of Medicine, Riyadh, Kingdom of Saudi Arabia.
authors.forename: M K
authors.initials: MK
authors.lastname: Alam
authors.forename: G S
authors.initials: GS
authors.lastname: el-Sayed
authors.forename: A M
authors.initials: AM
authors.lastname: Abdulmajeed
authors.forename: A
authors.initials: A
authors.lastname: al-Dohayan
mesh_terms: D000328:Adult; D004487:Edema / Q000209:etiology; D004932:Esophageal and Gastric Varices / Q000188:drug therapy / Q000601:surgery*; D004947:Esophagus / Q000098:blood supply; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D015911:Sclerotherapy; D017792:Surgical Stapling; D000267:Tissue Adhesions; D016896:Treatment Outcome