A pure brain metastasis of choriocarcinoma from a mixed germ cell tumor of the ovary.
We report a pure brain metastasis of choriocarcinoma from a mixed germ cell tumor of the ovary in a 19-year-old patient. This condition is extremely rare. Following abdominal operative procedures, multiple courses of combination chemotherapy, and resection of chemotherapy-resistant pulmonary metastases, a brain metastasis developed during chemotherapy. Craniotomy with resection of the neoplasm, brain radiation, and further chemotherapy was followed by disappearance of a pulmonary metastasis and long-term survival of the patient.
Adcock
L L
LL
Women's Cancer Center, University of Minnesota Medical School, Minneapolis 55455-0374, USA.
Oakley
G J
GJ
D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology / Q000556:secondary*; D002822:Choriocarcinoma / Q000473:pathology / Q000556:secondary*; D005260:Female; D018237:Germinoma / Q000473:pathology*; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000473:pathology*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000473:pathology*