Stopping and starting the meiotic cell cycle.
The meiotic cell cycle arrests in response to both perturbations and developmental signals. Recent research suggests that meiosis has checkpoints to monitor the completion of meiotic recombination and the attachment of chromosomes to the spindle. New insights have been gained into how meiosis resumes after normal developmental arrests, and new genes have been identified that are required for proper meiotic progression.
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Department of Biology, Massachusetts Institute of Technology and Whitehead Institute for Biomedical Research, 9 Cambridge Center Cambridge, Massachusetts 02142, USA. apage@wi.mit.edu
Orr-Weaver
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D000818:Animals; D002453:Cell Cycle / Q000502:physiology*; D006801:Humans; D008540:Meiosis / Q000502:physiology*; D009866:Oogenesis