title: [Studies of changes in filtration angle after experimental administration of ethacrynic acid into the anterior chamber].
abstract: The aim of the study is to determine what charges occur in filtration angle after administration of ethacrynic acid solution into anterior chamber. The study was conducted in 9 rabbits. After administration of 0.5 mmol/l and 0.7 mmol/l epsilon. acid solution, oedema of cells, relaxation of structure of trabecular texture and cellular necrobiosis in filtration angle were detected. Intraocular pressure lowered by 6-7 mm Hg. It is possible that ethacrynic acid will be used as an agent inducing changes in filtration angle which reduce intraocular pressure.
authors.affiliation: II Kliniki Okulistyki AM w Lublinie.
authors.forename: J
authors.initials: J
authors.lastname: Toczołowski
authors.forename: D
authors.initials: D
authors.lastname: Woźniak
mesh_terms: D000818:Animals; D000867:Anterior Chamber / Q000187:drug effects* / Q000473:pathology; D004976:Ethacrynic Acid / Q000494:pharmacology*; D007429:Intraocular Pressure / Q000187:drug effects; D011817:Rabbits; D014129:Trabecular Meshwork / Q000187:drug effects / Q000473:pathology
chemical_list: D004976:Ethacrynic Acid