Cutaneous mucormycosis with subsequent visceral dissemination in a child with neutropenia: a case report and review of the pediatric literature.
Primary cutaneous mucormycosis is a rare opportunistic fungal infection that is usually limited to the skin. We describe a primary cutaneous Rhizopus infection occurring at a site occluded by a sterile adhesive dressing in which the disease was viscerally disseminated at the time fo diagnosis. Mucormycosis should be considered in all ecthyma-like lesions in immunocompromised patients. It may be rapidly diagnosed by examination of hematoxylin-eosin and PAS-stained sections of the eschar base and a culture of a leading edge tissue aspirate. We review 21 cases of primary cutaneous mucormycosis in children and compare them with the present case.
Wirth
F
F
Department of Dermatology, University of Maryland School of Medicine, Baltimore, USA.
Perry
R
R
Eskenazi
A
A
Schwalbe
R
R
Kao
G
G
D002675:Child, Preschool; D006801:Humans; D008172:Lung Diseases, Fungal / Q000000981:diagnostic imaging / Q000209:etiology; D008297:Male; D009091:Mucormycosis / Q000209:etiology*; D009503:Neutropenia / Q000209:etiology*; D018962:Phlebotomy / Q000009:adverse effects*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D013158:Splenic Diseases / Q000000981:diagnostic imaging / Q000209:etiology; D014057:Tomography, X-Ray Computed