title: Aortic wall sarcoma with tumor emboli and peripheral ischemia: case report with review of literature.
abstract: Primary malignant tumors of the aorta are rare, only a handful of isolated cases having been described in the literature. Preoperative diagnosis of these tumors is more the exception than the rule. Diagnosis of aortic tumors is difficult as they can mimic many diverse conditions including atherosclerosis. We report a patient who presented with lower extremity claudication, renal infarction, and diffuse atherosclerosis and who was found to have tumor fragments in blood clots but no evidence of a primary tumor. Immunohistochemistry narrowed the differential diagnosis to a type of sarcoma. Six months later, he developed right flank pain due to a malignant fibrous histiocytoma that involved the abdominal aorta and that had initially manifested as tumor emboli.
authors.affiliation: Division of Hematology/Oncology, University of Connecticut Health Center, Farmington 06030, USA.
authors.forename: A
authors.initials: A
authors.lastname: Khan
authors.forename: F
authors.initials: F
authors.lastname: Jilani
authors.forename: S
authors.initials: S
authors.lastname: Kaye
authors.forename: B R
authors.initials: BR
authors.lastname: Greenberg
mesh_terms: D001018:Aortic Diseases / Q000150:complications / Q000175:diagnosis*; D001027:Aortography; D001161:Arteriosclerosis / Q000175:diagnosis*; D001344:Autopsy; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis; D006801:Humans; D007150:Immunohistochemistry; D007238:Infarction / Q000209:etiology*; D007383:Intermittent Claudication / Q000209:etiology*; D007668:Kidney / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D009360:Neoplastic Cells, Circulating; D012509:Sarcoma / Q000150:complications / Q000175:diagnosis*; D012983:Soft Tissue Neoplasms / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D019043:Vascular Neoplasms / Q000150:complications / Q000175:diagnosis*