[3-(1H-indol-3-yl)-4-(1-glykozylindol-3-yl)-1H-pyrrole-2,5-diones: synthesis and study of antiproliferative properties].
A synthesis of 3-(1H-3-indolyl)-4-(1-glycosyl-3-indolyl)furan-2,5-diones and -1H-pyrrole-2,5-diones modified with the residues of D-ribo-, D-xylo-, L-arabino-, D-galactopyranose, and D-lactose was described. Influence of the compounds prepared on DNA biosynthesis in CaOv cells was studied.
Mel'nik
S Ia
SIa
Bakhmedova
A A
AA
Garaeva
L D
LD
Miniker
T D
TD
Plikhtiak
I L
IL
Ektova
L V
LV
Ivanova
T P
TP
Adanin
V M
VM
Iartseva
I V
IV
D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D006027:Glycosides / Q000138:chemical synthesis* / Q000494:pharmacology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D014407:Tumor Cells, Cultured / Q000187:drug effects
D000970:Antineoplastic Agents; D006027:Glycosides