title: Prostate-specific antigen-producing cells in the bone marrow of a patient with early-stage prostate cancer.
abstract: This report describes a clinical case that supports the hypothesis that occult bone marrow disease may exist even in early-stage and low prostate-specific antigen (less than 10 ng/mL) prostate cancer. The concept of adding androgen suppression to definitive local therapy in these patients is discussed.
authors.affiliation: Joint Center for Radiation Therapy, Harvard Medical School, North Dartmouth, Massachusetts 02747, USA.
authors.forename: A V
authors.initials: AV
authors.lastname: D'Amico
authors.forename: H
authors.initials: H
authors.lastname: Matelski
authors.forename: M
authors.initials: M
authors.lastname: O'Leary
authors.forename: B
authors.initials: B
authors.lastname: Sussman
mesh_terms: D000368:Aged; D001853:Bone Marrow / Q000378:metabolism*; D001854:Bone Marrow Cells; D019046:Bone Marrow Neoplasms / Q000378:metabolism / Q000473:pathology / Q000556:secondary; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D017430:Prostate-Specific Antigen / Q000096:biosynthesis*; D011471:Prostatic Neoplasms / Q000378:metabolism* / Q000473:pathology
chemical_list: D017430:Prostate-Specific Antigen