Kinetic analysis of biosensor data: elementary tests for self-consistency.
The validity of the most common kinetic interpretation of biosensor data can be quickly assessed with the aid of two simple tests for self-consistency, requiring only back-of-the-envelope calculations. A search of the recent literature reveals that many published results fail these tests qualitatively.
Schuck
P
P
Section of Physical Biochemistry, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA. pschuck@helix.nih.gov
Minton
A P
AP
D015374:Biosensing Techniques / Q000592:standards*; D007700:Kinetics; D008962:Models, Theoretical; D015203:Reproducibility of Results