Long-term observation of a case of cutaneous blastomycosis in Poland treated with fluconazole.
The case of a 63-year-old carpenter with cutaneous blastomycosis is presented. The patient contracted the disease in 1974 when his leg was injured by a piece of rotten wood during repair works in deep cellars in Lublin's Old Town. Six months later a nodular lesion extending peripherally with hyperkeratosis developed at the site of the injury. The lesions slowly spread to cover more than half of the skin surface of the body. Some of them had regressed spontaneously, leaving cicatrization. Initially, anti-inflammatory treatment was given. Ten years later, in 1984, antimycotic therapy with various antifungal agents was instituted. Improvement appeared to be greatest with fluconazole treatment.
Chodorowska
G
G
Department of Dermatology, Medical Academy in Lublin, Poland.
Lecewicz-Toruń
B
B
D000038:Abscess / Q000473:pathology; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use*; D001758:Blastomyces / Q000145:classification / Q000302:isolation & purification; D001759:Blastomycosis / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011044:Poland; D012867:Skin / Q000382:microbiology / Q000473:pathology
D000893:Anti-Inflammatory Agents; D000935:Antifungal Agents; D015725:Fluconazole