title: [Chemotherapy-induced lung functional changes in patients with destructive pulmonary tuberculosis].
abstract: Lung function has been found to be altered in the overwhelming majority of patients with destructive pulmonary tuberculosis treated with drugs, only positive or only negative functional changes being relatively rarely observing. Combined positive and negative functional changes are much frequently revealed. The direction and magnitude of the revealed functional changes depend on the efficiency of tuberculosis treatment and on the specific features of a healing process. A thorough assessment of pulmonary functional changes can be made only on the basis of comprehensive studies of lung volumes, elasticity, and bronchial patency, by recording these parameters.
authors.affiliation: Central NII of Tuberculosis RAMN, Moscow.
authors.forename: V B
authors.initials: VB
authors.lastname: Nefedov
authors.forename: D G
authors.initials: DG
authors.lastname: Smirnova
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D008168:Lung / Q000187:drug effects / Q000503:physiopathology*; D012129:Respiratory Function Tests; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000503:physiopathology*
chemical_list: D000995:Antitubercular Agents