title: [The biological design of the oxygen transport system in mammals and the law of symmorphism].
abstract: In oxygen transport system of mammals the most important are biological constants and peculiarities of system construction, that are only hardly regulated physiologically. Thus, the coefficient of oxygen diffusion in animal tissues determines the construction of lungs and microvessel systems, oxygen capacity of blood, the rates of haemoglobin oxygenation and oxyhaemoglobin desoxygenation. The important parameter of biological construction of oxygen transport system is relatively low heart power (1-1.5 Vt for human). Such low value can be explained by low resistance to blood flow in microvessels because of decrease in blood viscosity. According the law of simmorphism physiological functions have a reserve that allows approximately ten times increase in power of functions. This law should be corrected since the supposed reserves in relatively small mammals are almost completely run off even in the stage of rest for maintenance of temperature homeostasis.
authors.forename: K P
authors.initials: KP
authors.lastname: Ivanov
mesh_terms: D000818:Animals; D001692:Biological Transport; D006224:Cricetinae; D004734:Energy Metabolism; D006706:Homeostasis; D006801:Humans; D008322:Mammals / Q000378:metabolism*; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption
chemical_list: D010100:Oxygen