[A single mechanism for the initiation of different effects of low doses of ionizing radiation].
Main regularities of different endpoints of low dose effects (adaptive response, stimulation of proliferation, special radiosensitivity of lymphoid cells, and others) have been examined. It has been shown that these endpoints have a commonness for the dose interval, the shape of the dose-effect curve, the reverse effect of dose rate, non-specificity toward initiating agents, and others. An explanation is suggested for the common mechanism of the initiation of all the studied low dose effects, basing on the theory of the non-specific reaction of cell to external influences. It is concluded that initiation of the low dose effects is conditioned by radiation induced damage of functions of plasmic and internal membranes.
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D000222:Adaptation, Physiological / Q000528:radiation effects; D000818:Animals; D001419:Bacteria / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D010101:Oxygen Consumption / Q000528:radiation effects; D010944:Plants / Q000528:radiation effects; D011830:Radiation Effects; D011836:Radiation Tolerance