title: Proton dosimetry in bone using electron spin resonance.
abstract: We have studied the ESR response of proton-irradiated (in vitro) bone. The ESR response as a function of proton (E = 105 MeV) dose to bone was linear from 0 to 50 Gy and similar to the photon (E = 6 MV) dose response. The ESR depth response (Bragg) curve was depressed as compared to a depth-response curve determined with a parallel plate ionization chamber (PPIC). There was a short-term ESR signal fade in the Bragg peak region, likely attributable to the organic component in bone. We are continuing to investigate these latter two effects.
authors.affiliation: Department of Physics, University of Massachusetts, Lowell 01854, USA.
authors.forename: J F
authors.initials: JF
authors.lastname: Copeland
authors.forename: K P
authors.initials: KP
authors.lastname: Gall
authors.forename: S Y
authors.initials: SY
authors.lastname: Lee
authors.forename: G E
authors.initials: GE
authors.lastname: Chabot
mesh_terms: D001842:Bone and Bones / Q000528:radiation effects*; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods* / Q000706:statistics & numerical data; D006801:Humans; D066298:In Vitro Techniques; D019047:Phantoms, Imaging; D061766:Proton Therapy; D011874:Radiometry / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy; D011522:Protons
chemical_list: D011522:Protons