title: Standards for the quantification of serial changes in the amniotic fluid index.
abstract: A total of 274 low-risk pregnancies underwent predetermined scheduled serial ultrasound examinations and measurements of the amniotic fluid index (AFI). As expected from previous cross-sectional studies, there is a gradual decline in the AFI from mid-trimester until term. The longitudinal nature of this data set permits the construction of conditional centiles for AFI whereby the AFI of an individual fetus at a given gestational age can be extrapolated to give a range of expected values for AFI (expressed as centiles) at a later gestational age. Examples of conditional centiles based upon 4-week measurement separations are presented. These conditional centiles permit the appropriate evaluation and quantification of time-dependent changes in AFI to be made.
authors.affiliation: Department of Obstetrics and Gynaecology, Ninewells Hospital and Medical School, Dundee, UK.
authors.forename: P
authors.initials: P
authors.lastname: Owen
authors.forename: S
authors.initials: S
authors.lastname: Ogston
mesh_terms: D000653:Amniotic Fluid / Q000000981:diagnostic imaging*; D001724:Birth Weight; D005314:Embryonic and Fetal Development; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D008137:Longitudinal Studies; D011247:Pregnancy; D011256:Pregnancy Outcome; D012307:Risk Factors; D016216:Ultrasonography, Prenatal