Re-resection for colorectal liver metastasis.
With the decreasing mortality and morbidity of liver resection in the last 10 years, a more aggressive approach has emerged against liver metastases of colorectal cancer. Repeat liver resection is being performed for patients with isolated liver recurrence following a first hepatectomy. Based on a 2-year experience of 55 repeat hepatic resections performed in 44 patients, the authors observed no operative mortality and a postoperative morbidity of 15% similar to that of first hepatectomies. Five-year survival rate is 44% following second hepatectomy. These results combined with the review of the literature demonstrate that rehapectomy may be performed safely and may provide the only chance of long-term remission in patients presenting with technically resectable liver recurrence in the absence of widespread extrahepatic disease.
Bismuth
H
H
Hepato-Biliary Surgery and Liver Transplant Unit, Paul Brousse Hospital and Faculty of Medicine Paris Sud, Villejuif, France.
Adam
R
R
Navarro
F
F
Castaing
D
D
Engerran
L
L
Abascal
A
A
D003110:Colonic Neoplasms / Q000473:pathology*; D006498:Hepatectomy / Q000009:adverse effects / Q000379:methods; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D018579:Patient Selection; D012004:Rectal Neoplasms / Q000473:pathology*; D012074:Remission Induction; D012086:Reoperation; D012449:Safety; D015996:Survival Rate