Activation, cellular redistribution and enhanced degradation of the G proteins Gq and G11 by endogenously expressed and transfected phospholipase C-coupled muscarinic m1 acetylcholine receptors.
Mullaney
I
I
Division of Biochemistry and Molecular Biology, University of Glasgow, UK.
Caulfield
M P
MP
Svoboda
P
P
Milligan
G
G
D000818:Animals; D016466:CHO Cells; D002217:Carbachol / Q000494:pharmacology; D006224:Cricetinae; D015536:Down-Regulation; D019204:GTP-Binding Proteins / Q000378:metabolism*; D015870:Gene Expression; D006801:Humans; D043643:Receptor, Muscarinic M1; D011976:Receptors, Muscarinic / Q000096:biosynthesis / Q000502:physiology*; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000378:metabolism; D014162:Transfection; D010738:Type C Phospholipases / Q000378:metabolism*
D043643:Receptor, Muscarinic M1; D011976:Receptors, Muscarinic; D011994:Recombinant Proteins; D002217:Carbachol; D010738:Type C Phospholipases; D019204:GTP-Binding Proteins