The effects of artery occlusion on temperature homogeneity during hyperthermia in rabbit kidneys in vivo.
To investigate the role of arterial occlusion on temperature homogeneity during hyperthermia for deep seated tissue, a renal hyperthermia animal model has been established using New Zealand white rabbits. The effects of ultrasound-induced renal hyperthermia, with or without continuous and intermittent renal artery occlusion, were compared and analysed. Both continuous and intermittent occlusion showed certain protection of surrounding tissue and demonstrated improved temperature homogeneity and heating efficiency. The benefits of continuous vs. intermittent occlusion are compared and discussed as well.
Jia
Z Q
ZQ
Division of Experimental Therapeutics, Ontario Cancer Institute, Toronto, Canada.
Worthington
A E
AE
Hill
R P
RP
Hunt
J W
JW
D000818:Animals; D001012:Aorta, Abdominal; D005260:Female; D006651:Histocytochemistry; D006979:Hyperthermia, Induced; D007511:Ischemia / Q000378:metabolism; D007668:Kidney / Q000098:blood supply / Q000473:pathology / Q000502:physiology*; D008026:Ligation; D011817:Rabbits; D012077:Renal Artery; D012079:Renal Circulation; D013696:Temperature; D013997:Time Factors