title: Idiopathic granulomatous angiitis of the central nervous system in pregnancy: the first case report.
abstract: Idiopathic granulomatous angiitis of the central nervous system (IGANS) is a rare vasculitis primarily affecting the spinal cord and brain not related to any underlying systemic disease. Clinical manifestations range from simple headache to cerebral vascular accidents secondary to vascular occlusion. The management of a pregnancy complicated by multiple risk factors including underlying IGANS is reported. An expectant, empiric approach was adopted and resulted in excellent maternal and neonatal outcomes. The first report of the management of a pregnancy complicated by IGANS is presented. Underlying maternal IGANS may not necessarily represent an indication for pregnancy termination.
authors.affiliation: Department of Obstetrics and Gynecology, Sinai Hospital, Wayne State University School of Medicine, Detroit, Michigan, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Barrionuevo
authors.forename: R A
authors.initials: RA
authors.lastname: Bronsteen
authors.forename: L M
authors.initials: LM
authors.lastname: Eilender
authors.forename: D J
authors.initials: DJ
authors.lastname: Wright
authors.forename: G L
authors.initials: GL
authors.lastname: Goyert
mesh_terms: D000328:Adult; D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000503:physiopathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D008297:Male; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis / Q000503:physiopathology*; D011256:Pregnancy Outcome; D011254:Pregnancy in Diabetics / Q000175:diagnosis / Q000503:physiopathology; D014657:Vasculitis / Q000175:diagnosis / Q000503:physiopathology*