title: The possibility of predicting tissue accumulation after repeated dosing using a single-dose tissue distribution study.
authors.affiliation: Department of Drug Metabolism and Disposition, Shionogi & Co., Ltd., Osaka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Mizojiri
authors.forename: H
authors.initials: H
authors.lastname: Shindo
authors.forename: Y
authors.initials: Y
authors.lastname: Ohno
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D064420:Drug-Related Side Effects and Adverse Reactions; D011237:Predictive Value of Tests; D051381:Rats; D018570:Risk Assessment; D014018:Tissue Distribution; D018675:Toxicity Tests / Q000592:standards* / Q000706:statistics & numerical data