Serum total antioxidant activity after myocardial infarction.
Serum total antioxidant activity (TAA), albumin and uric acid were measured on admission, and for the next 2 days in 56 patients suffering myocardial infarction, 20 of whom received streptokinase. The 'antioxidant gap', the difference between the serum TAA and the sum of the serum albumin and uric acid activity, was calculated. No significant changes in serum total antioxidant activity were observed in either group of patients between admission, day 1 and day 2. However, a decline in the 'antioxidant gap' after myocardial infarction was associated with a significantly higher mortality.
Miller
N J
NJ
Division of Biochemistry and Molecular Biology, United Medical School, Guy's Hospital, London, UK.
Johnston
J D
JD
Collis
C S
CS
Rice-Evans
C
C
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000975:Antioxidants / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood / Q000378:metabolism* / Q000628:therapy*; D051437:Renal Insufficiency / Q000150:complications; D012709:Serum Albumin / Q000378:metabolism; D013300:Streptokinase / Q000627:therapeutic use; D015912:Thrombolytic Therapy; D013997:Time Factors; D014527:Uric Acid / Q000097:blood / Q000378:metabolism
D000975:Antioxidants; D012709:Serum Albumin; D014527:Uric Acid; D013300:Streptokinase