title: [Serotonin in diabetic retinopathy].
abstract: OBJECTIVE
  The present study was designed to evaluate a possible participation of serotonin in the development of retinopathy in diabetes mellitus.
  
  
  METHODS
  Serotonin of whole blood and platelets was studied in 12 patients with Type I and II diabetes using high pressure liquid chromatography method.
  
  
  RESULTS
  The concentration of serotonin in the blood was markedly increased (210 +/- 50 ng/ml in diabetes and 150 +/- 35 ng/ml in control, p < 0.01) and not changed in platelets in diabetes. There was a relation between blood serotonin level and the presence of retinopathy.
  
  
  CONCLUSIONS
  These results suggest that serotonin may be involved in the pathogenesis of diabetic microangiopathy.
authors.affiliation: Kliniki Okulistycznej AM w Białymstoku.
authors.forename: J
authors.initials: J
authors.lastname: Andrzejewska-Buczko
authors.forename: D
authors.initials: D
authors.lastname: Pawlak
authors.forename: M
authors.initials: M
authors.lastname: Walkowiak
authors.forename: A
authors.initials: A
authors.lastname: Stankiewicz
mesh_terms: D000368:Aged; D001792:Blood Platelets / Q000737:chemistry; D003920:Diabetes Mellitus / Q000097:blood; D003930:Diabetic Retinopathy / Q000097:blood*; D005260:Female; D006801:Humans; D012701:Serotonin / Q000097:blood*
chemical_list: D012701:Serotonin