title: Abc1: a new ABC transporter from the fission yeast Schizosaccharomyces pombe.
abstract: We have isolated the abc1 gene from the fission yeast Schizosaccharomyces pombe. Sequence analysis suggests that the Abc1 protein is a member of the ABC superfamily of transporters and is composed of two structurally homologous halves, each consisting of a hydrophobic region of six transmembrane domains and a hydrophilic region containing one ATP-binding site. The abc1 gene appears to be expressed under all growth conditions but gene disruption experiments indicate that it is not essential for growth. The sequence of the abc1 gene has been deposited in the EMBL data library under the Accession Number Y09354.
authors.affiliation: Department of Genetics, University of Copenhagen, Denmark.
authors.forename: P U
authors.initials: PU
authors.lastname: Christensen
authors.forename: K
authors.initials: K
authors.lastname: Davis
authors.forename: O
authors.initials: O
authors.lastname: Nielsen
authors.forename: J
authors.initials: J
authors.lastname: Davey
mesh_terms: D018528:ATP-Binding Cassette Transporters / Q000235:genetics; D004271:DNA, Fungal / Q000032:analysis; D005656:Fungal Proteins / Q000235:genetics*; D005800:Genes, Fungal / Q000235:genetics; D008969:Molecular Sequence Data; D016296:Mutagenesis / Q000235:genetics; D012568:Schizosaccharomyces / Q000737:chemistry* / Q000235:genetics* / Q000378:metabolism; D029702:Schizosaccharomyces pombe Proteins; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
chemical_list: C099890:ABC1 protein, S pombe; D018528:ATP-Binding Cassette Transporters; D004271:DNA, Fungal; D005656:Fungal Proteins; D029702:Schizosaccharomyces pombe Proteins