Carbamazepine-associated acute tubulointerstitial nephritis.
The case history of a patient developing tubulointerstitial nephritis (TIN) during carbamazepine therapy is described. After withdrawal of the drug and introduction of prednisone renal function normalised. TIN is a rare side-effect of carbamazepine of which only a few cases have been described. There seems to be a remarkable time interval of 2 months between the onset of therapy with carbamazepine and the development of TIN.
Eijgenraam
J W
JW
Department of Internal Medicine, Westeinde Hospital, The Hague, Netherlands.
Buurke
E J
EJ
van der Laan
J S
JS
D000208:Acute Disease; D000368:Aged; D000927:Anticonvulsants / Q000009:adverse effects*; D001706:Biopsy; D002220:Carbamazepine / Q000009:adverse effects*; D004827:Epilepsy / Q000150:complications / Q000188:drug therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000187:drug effects / Q000503:physiopathology; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000473:pathology / Q000628:therapy
D000927:Anticonvulsants; D002220:Carbamazepine