title: [Myositis--a rare complication of Crohn disease].
abstract: Crohn's disease is a chronic relapsing inflammatory disorder primarily affecting the gastrointestinal system. Extraintestinal manifestations such as erythema nodosum, iridocyclitis, arthritis and sclerosing cholangitis are frequent. We report on a 57-year old male patient with the symptoms of Crohn's disease. Clinically he showed signs of a muscle disorder and muscle biopsy demonstrated a perimysial inflammation with lymphocytes and histiocytes. Complete remission was achieved by immunosuppressive treatment. Six cases presented in the literature are reviewed and the autoimmunological aspects of the pathogenesis discussed.
authors.affiliation: Neurologische Klinik mit Poliklinik, Universität Erlange-Nürnberg.
authors.forename: A
authors.initials: A
authors.lastname: Druschky
authors.forename: J
authors.initials: J
authors.lastname: Heckmann
authors.forename: A
authors.initials: A
authors.lastname: Engelhardt
authors.lastname: Neundörfer
mesh_terms: D001379:Azathioprine / Q000008:administration & dosage; D001706:Biopsy; D003424:Crohn Disease / Q000188:drug therapy / Q000473:pathology*; D004359:Drug Therapy, Combination; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000473:pathology; D009220:Myositis / Q000188:drug therapy / Q000473:pathology*; D012460:Sulfasalazine / Q000008:administration & dosage
chemical_list: D012460:Sulfasalazine; D001379:Azathioprine; D008775:Methylprednisolone