title: Radiological and clinical recurrence of giant-cell tumour of bone after the use of cement.
abstract: We have reviewed 13 operations on 11 patients using curettage and polymethylmethacrylate cement for giant-cell tumour of bone (GCT) to assess the value of radiology in the early detection of recurrence. There were four recurrences, the most specific radiological sign on plain radiography was lysis of 5 mm or more at the cement-bone interface. This preceded clinical signs by a mean of four months and was identified at a mean of 3.75 months after operation. There was not always a complete sclerotic margin around the cement, but when it was present, there was never evidence of recurrence. MRI was helpful in assessing cases with evidence of recurrence. Frequent surveillance with plain radiography should continue for one year after operation irrespective of clinical signs of recurrence. When the appearance of the plain radiographs suggests recurrence, MRI should be performed and followed by image-guided needle biopsy.
authors.affiliation: The Royal National Orthopaedic Hospital Trust and London Bone Tumour Service, Stanmore, Middlesex, UK.
authors.forename: D
authors.initials: D
authors.lastname: Remedios
authors.forename: A
authors.initials: A
authors.lastname: Saifuddin
authors.forename: J
authors.initials: J
authors.lastname: Pringle
mesh_terms: D000328:Adult; D001843:Bone Cements; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D005260:Female; D018212:Giant Cell Tumor of Bone / Q000000981:diagnostic imaging* / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging; D011859:Radiography
chemical_list: D001843:Bone Cements