Cytogenetic characteristics of ectopic pregnancy.
During a 12 month period, tissue was collected from 30 surgically managed patients presenting with vital ectopic pregnancies. Chorionic villi of the removed tissue were successfully karyotyped by (semi-) direct chromosome technique in 22 cases. Only one abnormal chromosomal complement, a triploidy (69,XXX) was found. As controls, 10 cases of intrauterine pregnancies were investigated, all showing a normal karyotype. These findings do not suggest an important role for chromosome abnormalities in the aetiology of vital ectopic pregnancies.
Goddijn
M
M
Department of Obstetrics & Gynaecology, University of Amsterdam, The Netherlands.
van der Veen
F
F
Schuring-Blom
G H
GH
Ankum
W M
WM
Leschot
N J
NJ
D000328:Adult; D002824:Chorionic Villi / Q000648:ultrastructure; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000235:genetics*; D011446:Prospective Studies; D014314:Trisomy; D014960:X Chromosome