title: Five-year longitudinal study on limited food consumption and development of osteoarthritis in coxofemoral joints of dogs.
abstract: OBJECTIVE
  To examine the effects of limited food intake on frequency and severity of osteoarthritis in coxofemoral joints of labrador Retrievers.
  
  
  METHODS
  Dogs were paired according to gender and body weight, within each litter at 8 weeks of age. One dog of each pair was fed ad libitum. The limit-fed pairmate was fed 75% of the amount eaten the previous day by the ad libitum-fed counterpart.
  
  
  METHODS
  48 Labrador Retrievers.
  
  
  METHODS
  All dogs received the same diet. Radiographic evaluation of coxofemoral joints for frequency and severity of osteoarthritis were made when dogs were 4 and 6 months and 1, 2, 3, and 5 years old.
  
  
  RESULTS
  Radiographic evaluation for osteoarthritis indicated greater frequency and more severity of osteoarthritis in the ad libitum-fed group of dogs.
  
  
  CONCLUSIONS
  Analysis of data suggested that limit feeding of dogs over a 5-year period minimizes development of osteoarthritis in the coxofemoral joints.
authors.affiliation: Pet Products Research and Development, Ralston Purina Co, St. Louis, MO 63164, USA.
authors.forename: R D
authors.initials: RD
authors.lastname: Kealy
authors.forename: D F
authors.initials: DF
authors.lastname: Lawler
authors.forename: J M
authors.initials: JM
authors.lastname: Ballam
authors.forename: G
authors.initials: G
authors.lastname: Lust
authors.forename: G K
authors.initials: GK
authors.lastname: Smith
authors.forename: D N
authors.initials: DN
authors.lastname: Biery
authors.forename: S E
authors.initials: SE
authors.lastname: Olsson
mesh_terms: D000818:Animals; D001835:Body Weight; D018753:Diet, Protein-Restricted / Q000662:veterinary; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000517:prevention & control*; D004285:Dogs; D002149:Energy Intake; D005260:Female; D005508:Food Deprivation; D006619:Hip Dysplasia, Canine / Q000453:epidemiology; D006621:Hip Joint / Q000000981:diagnostic imaging; D016014:Linear Models; D008137:Longitudinal Studies; D008297:Male; D010003:Osteoarthritis / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000517:prevention & control / Q000662:veterinary*; D015995:Prevalence; D011859:Radiography; D012307:Risk Factors; D012720:Severity of Illness Index