title: Mitochondrial encephalomyopathy with elderly onset of stroke-like episodes.
abstract: A 52-year-old woman with a history of a hearing disturbance since age 20 experienced visual hallucinations and convulsions, followed by right hemiparesis and aphasia. On the basis of a muscle biopsy and mitochondrial DNA analysis, she was diagnosed as mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes (MELAS). This case is unique in that the stroke-like episodes occurred 30 years after disease onset.
authors.affiliation: Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya.
authors.forename: H
authors.initials: H
authors.lastname: Minamoto
authors.forename: K
authors.initials: K
authors.lastname: Kawabata
authors.forename: B
authors.initials: B
authors.lastname: Okuda
authors.forename: N
authors.initials: N
authors.lastname: Shibuya
authors.forename: H
authors.initials: H
authors.lastname: Tachibana
authors.forename: M
authors.initials: M
authors.lastname: Sugita
authors.forename: Y
authors.initials: Y
authors.lastname: Goto
authors.forename: I
authors.initials: I
authors.lastname: Nishino
authors.forename: I
authors.initials: I
authors.lastname: Nonaka
mesh_terms: D017668:Age of Onset; D001921:Brain / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D017241:MELAS Syndrome / Q000503:physiopathology*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D017237:Mitochondrial Encephalomyopathies