The dangers of dextropropoxyphene.
OBJECTIVE
Dextropropoxyphene is a commonly used analgesic despite its high toxicity in overdose and potential for abuse and dependence. This case report highlights these dangers.


METHODS
The case of a female who was addicted to dextropropoxyphene as an alternative to other opioids is described. Its use in high doses with other psychotropic agents resulted in adverse health effects.


METHODS
The patient was treated with methadone and psychosocial interventions.


RESULTS
The patient reduced her drug use and experienced improved physical health and psychosocial functioning.


CONCLUSIONS
Caution is needed when prescribing dextropropoxyphene because of its adverse effects compared with equally efficacious analgesics.
Dore
G M
GM
Dunedin School of Medicine, University of Otago, New Zealand.
D000328:Adult; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000009:adverse effects*; D003131:Combined Modality Therapy; D011431:Dextropropoxyphene / Q000009:adverse effects*; D062787:Drug Overdose; D005260:Female; D006801:Humans; D008691:Methadone / Q000627:therapeutic use*; D011613:Psychotherapy; D019966:Substance-Related Disorders / Q000534:rehabilitation*
D000701:Analgesics, Opioid; D011431:Dextropropoxyphene; D008691:Methadone