title: Transcutaneous and arterial carbon dioxide tension at various conditions of fetal stress in lambs.
abstract: In an acute fetal lamb model the relation between arterial PCO2 (PaCO2), transcutaneous PCO2 (tcPCO2) and pH was studied at different conditions of stress. Occlusion of the maternal common iliac artery for 8 min, umbilical cord obstruction for 5 min and placental embolization were performed subsequently, every time with an interval of 1 h for fetal recuperation. During the first 2 experiments arterial values changed rapidly after occlusion and returned nearly to normal within 30-60 min after the end of occlusion. TcPCO2 started to increase several minutes after occlusion and reached its maximum about 5 min after the end of occlusion. Afterwards a gradual decrease towards the onset value was observed. During placental embolization tcPCO2 did not increase until 15 min before fetal death. It is concluded that tcPCO2 can follow a gradual trend, but not quick changes in PaCO2.
authors.affiliation: Department of Obstetrics and Gynaecology, St. Laurentiusziekenhuis, Roermond, The Netherlands.
authors.forename: M G
authors.initials: MG
authors.lastname: Bergmans
authors.forename: G H
authors.initials: GH
authors.lastname: Stevens
authors.forename: H
authors.initials: H
authors.lastname: Keunen
authors.forename: T H
authors.initials: TH
authors.lastname: Hasaart
mesh_terms: D000137:Acid-Base Imbalance / Q000097:blood; D000818:Animals; D001785:Blood Gas Monitoring, Transcutaneous; D002245:Carbon Dioxide / Q000097:blood*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D005315:Fetal Diseases / Q000097:blood* / Q000196:embryology; D006863:Hydrogen-Ion Concentration; D007083:Iliac Artery / Q000033:anatomy & histology*; D008431:Maternal-Fetal Exchange / Q000502:physiology; D010920:Placenta / Q000098:blood supply*; D011247:Pregnancy; D012756:Sheep; D013312:Stress, Physiological / Q000097:blood* / Q000196:embryology; D013997:Time Factors; D014470:Umbilical Cord / Q000098:blood supply*
chemical_list: D002245:Carbon Dioxide