Buschke-Löwenstein tumor and immunity.
We report the case of an alcoholic patient, 41 years old, with negative results of serologic tests for human immunodeficiency virus (HIV) with a perianal Buschke-Löwenstein tumor present for eight years and exceptionally large. The patient's cell-mediated immunity was evaluated by two functional tests: the Multitest IMC (Institut Mérieux, Lyon) and the dinitrochlorobenzene (DNCB) test. The patient neither responded to any Multitest antigens nor was sensitized by DNCB. We consider that the immune short-age in this patient could influence the appearance of the Buschke-Löwenstein tumor.
González-López
A
A
Department of Dermatology, University Hospital of Valladolid, Spain.
Esquivias
J I
JI
Miranda-Romero
A
A
Massa
C F
CF
Tejerina
J A
JA
Blasco
M J
MJ
D000328:Adult; D001004:Anus Diseases / Q000175:diagnosis / Q000276:immunology / Q000473:pathology / Q000628:therapy; D003218:Condylomata Acuminata / Q000175:diagnosis / Q000276:immunology / Q000473:pathology / Q000628:therapy; D006801:Humans; D007111:Immunity, Cellular; D008297:Male; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000175:diagnosis / Q000276:immunology / Q000473:pathology / Q000628:therapy; D014412:Tumor Virus Infections / Q000175:diagnosis / Q000276:immunology / Q000473:pathology / Q000628:therapy