title: Optical imaging of anatomical maps derived from magnetic resonance images using time-independent optical sources.
abstract: We present a model suitable for computing images of absorption cross sections of thick tissue structures illuminated at near infrared (NIR) wavelengths from tomographic projection data. Image reconstruction is accomplished by solving a system of linear equations derived from transport theory. Reconstruction results using different algebraic solvers are shown for anatomical maps of the breast, derived from magnetic resonance imaging data, containing two simulated pathologies, in which case qualitatively good reconstructions were obtained. Evaluation of magnetic resonance (MR) data to optimize NIR optical tomographic imaging methods and to assess the feasibility of a combined MR-optical measurement scheme is discussed.
authors.affiliation: Department of Pathology, SUNY Health Science Center at Brooklyn 11203, USA.
authors.forename: J
authors.initials: J
authors.lastname: Chang
authors.forename: H L
authors.initials: HL
authors.lastname: Graber
authors.forename: P C
authors.initials: PC
authors.lastname: Koo
authors.forename: R
authors.initials: R
authors.lastname: Aronson
authors.forename: S L
authors.initials: SL
authors.lastname: Barbour
authors.forename: R L
authors.initials: RL
authors.lastname: Barbour
mesh_terms: D000273:Adipose Tissue / Q000033:anatomy & histology; D000465:Algorithms; D019412:Anatomy, Cross-Sectional; D001940:Breast / Q000033:anatomy & histology*; D001941:Breast Diseases / Q000175:diagnosis / Q000473:pathology; D003198:Computer Simulation; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D007259:Infrared Rays; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009558:Nipples / Q000033:anatomy & histology; D019047:Phantoms, Imaging; D013909:Thorax / Q000033:anatomy & histology; D014054:Tomography