title: [A biological compatibility study of hydroxyapatite].
abstract: The biological compatibility of coatings of subcutaneous implants was studied in rat experiments. The implants were coated with hydroxyapatite and hydroxyapatite modified by chloromethylsilanthrane (silamine). The coatings were found to inhibit lipid peroxidation and form the optimal ratio of connective tissue biopolymers in capsules forming round the implants. Both types of hydroxyapatites used were characterized by high biological compatibility.
authors.forename: V V
authors.initials: VV
authors.lastname: Trofimov
authors.forename: V A
authors.initials: VA
authors.lastname: Klimenov
authors.forename: V B
authors.initials: VB
authors.lastname: Kazimirovskaia
authors.forename: L A
authors.initials: LA
authors.lastname: Mansurova
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology* / Q000633:toxicity; D001704:Biopolymers; D003094:Collagen / Q000494:pharmacology / Q000633:toxicity; D015921:Dental Implants; D003764:Dental Materials / Q000494:pharmacology* / Q000633:toxicity; D004338:Drug Combinations; D017886:Durapatite / Q000494:pharmacology* / Q000633:toxicity; D007928:Lethal Dose 50; D015227:Lipid Peroxidation / Q000187:drug effects; D008422:Materials Testing / Q000379:methods / Q000706:statistics & numerical data; D051379:Mice; D017646:Organosilicon Compounds / Q000494:pharmacology / Q000633:toxicity; D011817:Rabbits; D051381:Rats; D014025:Titanium
chemical_list: D001672:Biocompatible Materials; D001704:Biopolymers; D015921:Dental Implants; D003764:Dental Materials; D004338:Drug Combinations; D017646:Organosilicon Compounds; C104011:Silimin; C033818:1-(chloromethyl)silatrane; D003094:Collagen; D017886:Durapatite; D014025:Titanium
vernacular_title: Issledovanie biologicheskoĭ sovmestimosti gidroksiapatita.