title: A single gene encodes a selective toxin causal to the development of tan spot of wheat.
abstract: The identification and characterization of pathogenicity factors are essential to an understanding of the molecular events that regulate the interaction of plant-pathogenic microbes with their hosts. We have isolated the gene that encodes a host-selective toxic protein produced by the fungus Pyrenophora tritici-repentis and confirmed that this gene functions in the plant as the primary determinant of pathogenicity in the Pyrenophora-wheat interaction. These results demonstrate that a single gene encodes the production of a host-selective toxin and that transformation of this gene into a non-toxin-producing isolate of P. tritici-repentis leads to both toxin production and pathogenicity.
authors.affiliation: Department of Botany and Plant Pathology, Oregon State University, Corvallis 97331, USA.
authors.forename: L M
authors.initials: LM
authors.lastname: Ciuffetti
authors.forename: R P
authors.initials: RP
authors.lastname: Tuori
authors.forename: J M
authors.initials: JM
authors.lastname: Gaventa
mesh_terms: D000595:Amino Acid Sequence; D001203:Ascomycota / Q000235:genetics / Q000472:pathogenicity*; D001483:Base Sequence; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000737:chemistry; D005656:Fungal Proteins; D008969:Molecular Sequence Data; D009181:Mycoses / Q000235:genetics*; D009183:Mycotoxins / Q000737:chemistry / Q000235:genetics*; D010935:Plant Diseases / Q000235:genetics*; D014908:Triticum
chemical_list: D018076:DNA, Complementary; D005656:Fungal Proteins; D009183:Mycotoxins; C105776:TOXA protein, Pyrenophora tritici-repentis