Phagocytosis-enhancing effect of lactoferrin on bovine peripheral blood monocytes in vitro and in vivo.
The effect of lactoferrin (LF) on in vitro and in vivo phagocytic ability of bovine blood monocytes was studied. It was demonstrated that bovine LF enhanced in vitro phagocytosis of bacteria and ovine erythrocyte-antibody complexes and increased intracellular killing of Staphylococcus albus. Monocytes of colostrum deprived calves, which were intravenously injected with LF, also exhibited elevated phagocytic properties.
Szuster-Ciesielska
A
A
Department of Applied Microbiology, Maria Curie-Skłodowska University, Lublin, Poland.
Kamińska
T
T
Kandefer-Szerszeń
M
M
D000818:Animals; D002417:Cattle / Q000097:blood* / Q000502:physiology*; D004912:Erythrocytes / Q000166:cytology / Q000502:physiology; D005260:Female; D066298:In Vitro Techniques; D007275:Injections, Intravenous; D007781:Lactoferrin / Q000008:administration & dosage / Q000494:pharmacology*; D008070:Lipopolysaccharides / Q000494:pharmacology; D009000:Monocytes / Q000166:cytology / Q000187:drug effects* / Q000502:physiology; D010587:Phagocytosis / Q000187:drug effects* / Q000502:physiology; D013210:Staphylococcus / Q000276:immunology
D008070:Lipopolysaccharides; D007781:Lactoferrin