Expression of an abnormal sized c-kit transcript in Hong Kong Chinese acute lymphoblastic leukaemia patients.
Blast cells from a majority of acute myelogenous leukaemia (AML) patients express c-kit mRNA. However, c-kit expression has not been observed in patients with acute lymphoblastic leukaemia (ALL) and lymphoproliferative disease. We report here the detection of an abnormal sized c-kit mRNA in two Hong Kong Chinese patients with pre-B ALL and common ALL.
Chui
C H
CH
Department of Pathology, Faculty of Medicine, The University of Hong Kong.
Lau
F Y
FY
Chan
A H
AH
Tang
J C
JC
Hui
C H
CH
Lam
C C
CC
Chan
L C
LC
Cheng
G
G
D000328:Adult; D001853:Bone Marrow / Q000502:physiology; D002648:Child; D002681:China / Q000208:ethnology; D004247:DNA / Q000032:analysis; D005260:Female; D005784:Gene Amplification / Q000235:genetics; D015973:Gene Expression Regulation, Leukemic / Q000235:genetics* / Q000502:physiology; D015321:Gene Rearrangement / Q000235:genetics; D006723:Hong Kong; D006801:Humans; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics / Q000503:physiopathology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics* / Q000503:physiopathology; D019009:Proto-Oncogene Proteins c-kit / Q000235:genetics*; D012334:RNA, Neoplasm / Q000235:genetics* / Q000502:physiology; D014158:Transcription, Genetic
D012334:RNA, Neoplasm; D004247:DNA; D019009:Proto-Oncogene Proteins c-kit