Identification and classification of tibioperoneal diaphyseal toxopachyosteosis (Weismann-Netter-Stuhl syndrome): based on two new cases and a review of the literature.
Using two new cases and 70 case reports in the literature as a starting point, the authors focus on the Weismann-Netter-Stuhl syndrome. Weismann-Netter and Stuhl reported the first cases of tibioperoneal diaphyseal toxopachyosteosis in 1954. This syndrome is defined as an anomaly of the diaphyseal part of both tibiae and fibulae with posterior cortical thickening and anterior-posterior bowing. This anomaly is usually bilateral and symmetrical and patients are short. The thickening of the fibula is true tibialisation and is the main feature and the only feature confirming diagnosis. Routine laboratory investigations showed no abnormalities. The authors specify the limits encountered in classifying this anomaly and discuss the degree to which this anomaly is an entity unto itself when compared with rickets sequelae.
Nor 3es
J M
JM
Internal Medicine Department, Raymond Poincaré Hospital, Garches, France.
Monsegu
M H
MH
de Masfrand
V
V
Oberlin
F
F
Denormandie
P
P
Rémy
J M
JM
D001827:Body Height; D018483:Diaphyses / Q000002:abnormalities; D005269:Femur / Q000002:abnormalities; D005360:Fibula / Q000002:abnormalities* / Q000000981:diagnostic imaging; D006801:Humans; D007870:Leg Length Inequality / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012279:Rickets / Q000473:pathology; D013577:Syndrome; D013977:Tibia / Q000002:abnormalities* / Q000000981:diagnostic imaging