[The stabilizing effect of enterosgel on the structural bases of membrane digestion and absorption in the small intestine in severe thermal skin burns].
Enterosgel effect on morphofunctional indices of the small intestine has been ascertained in experiments on animals, histochemical, electron-microscopic and morphometric methods being used. Enterosorbent in the dose of 0.3 g/kg body weight was injected orally to the guinea-pigs for 14 days. The results of the investigations prove the severe burn traumas to result in sufficient structural changes in the small intestine wall which causes impairment of membranous digestion processes and absorption of nutrients. It is to be noted that the developing burn disease results in the increase of changes severity and reaches the highest values at the stage of septicotoxemia. The enterosorbent assessed positively affects morphofunctional values of the small intestine. The enterosorbent does not enhance conventional development of the pathologic process but considerably decreases its manifestation. The enterosgel promotes the improvement of membranous digestion and absorption in the small intestine, increasing alkaline phosphatase action and rising the number of endocellular vesicles in epitheliocytes having brush margins.
Pasechka
N V
NV
D000818:Animals; D002056:Burns / Q000378:metabolism / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*; D004063:Digestion / Q000502:physiology*; D016061:Enterosorption; D005782:Gels; D006168:Guinea Pigs; D006651:Histocytochemistry; D007408:Intestinal Absorption / Q000502:physiology*; D007421:Intestine, Small / Q000378:metabolism / Q000503:physiopathology* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D012828:Silicones / Q000627:therapeutic use*; D012867:Skin / Q000293:injuries*; D013997:Time Factors
D005782:Gels; D012828:Silicones; C078211:polymethylsiloxane
Stabilizuiuchyĭ vplyv enterosheliu na strukturni osnovy membrannoho travlennia ta vsmoktuvannia v tonkiĭ kyshtsi pry vazhnykh termichnykh opikakh shkiry.