title: Corneal temperature changes during photorefractive keratectomy.
abstract: OBJECTIVE
  Corneal temperature changes in photorefractive keratectomy (PRK) have been implicated in the aetiology of subepithelial haze. This study was undertaken to quantify the temperature change during this surgical procedure.
  
  
  METHODS
  Non-contact, colour-coded ocular thermography was performed by using an infrared detection system during PRK on a group of 12 subjects.
  
  
  RESULTS
  Mean (+/-SD) central ocular surface temperature (OST) after epithelial debridement was 29.15 +/- 0.39 degrees C. Mean peak OST during PRK was 37.77 +/- 0.67 degrees C, with most of the temperature increase occurring during the first 15 s. Factors such as ablation depth, optical correction, and procedure duration were not demonstrated to have a significant effect on corneal temperature during the procedure, suggesting a complex relation between-PRK parameters and the change in corneal temperature.
  
  
  CONCLUSIONS
  Previous work suggested that corneal collagen denatures at approximately 39 degrees C, and it has been demonstrated that corneal temperature may be elevated to this level during routine PRK. Further research is indicated into the effects of preoperative cooling and pausing in treatment to reduce temperature changes.
authors.affiliation: Department of Optometry and Vision Sciences, University of Manchester Institute of Science and Technology, England.
authors.forename: S
authors.initials: S
authors.lastname: Betney
authors.forename: P B
authors.initials: PB
authors.lastname: Morgan
authors.forename: S J
authors.initials: SJ
authors.lastname: Doyle
authors.forename: N
authors.initials: N
authors.lastname: Efron
mesh_terms: D003094:Collagen / Q000378:metabolism; D003315:Cornea / Q000378:metabolism / Q000503:physiopathology* / Q000601:surgery; D003316:Corneal Diseases / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D054018:Lasers, Excimer; D018903:Photorefractive Keratectomy; D011489:Protein Denaturation; D013696:Temperature; D014792:Visual Acuity
chemical_list: D003094:Collagen