title: [Diagnosis of Epstein-Barr virus-associated gastric carcinoma and its background gastric mucosa].
abstract: Recently, the presence of Epstein-Barr virus(EBV) in almost 7% of gastric carcinoma lesions was reported. From our observation, EBV-associated gastric carcinomas located mainly in the gastric body, and moderate to poorly differentiated adenocarcinoma with lymphoid infiltration, as currently reported. Macroscopically, there were mainly thick and ulcerated lesions, EBV-associated gastric carcinomas had close relation with intestinal metaplasia, and EBV could be suspected to provide the immortalized epithelial cells.
authors.affiliation: First Department of Internal Medicine, Yamaguchi University School of Medicine.
authors.forename: H
authors.initials: H
authors.lastname: Yanai
authors.forename: Y
authors.initials: Y
authors.lastname: Mizugaki
authors.forename: J
authors.initials: J
authors.lastname: Nishikawa
authors.forename: M
authors.initials: M
authors.lastname: Tada
authors.forename: K
authors.initials: K
authors.lastname: Okita
authors.forename: N
authors.initials: N
authors.lastname: Shimizu
authors.forename: K
authors.initials: K
authors.lastname: Takada
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology; D005753:Gastric Mucosa / Q000473:pathology; D006566:Herpesviridae Infections / Q000473:pathology*; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014412:Tumor Virus Infections / Q000473:pathology*