title: [Beta-blockers in the treatment of open-angle glaucoma].
abstract: Authors report the results of comparative study of three betablockers used in the treatment of primary open-angle glaucoma commonly available on the market. The influence of non-selective betablockers (TIMOPTOL 0.5%, VISTAGAN 0.5%) and selective betablocker (BETOPTIC 0.5%) on the intraocular pressure, pulse frequency, systemic blood pressure and lung capacity was evaluated. Three different groups, each of 20 patients with newly diagnosed primary openangle glaucoma were assigned to be treated by studied drugs independently. Authors conclude that all three drugs reliably lowered intraocular pressure. BETOPTIC and VISTAGAN did not influence on pulse frequency, blood pressure and lung capacity. Apart from the fact that VISTAGAN is considered to be non-selective betablocker, its efficacy is comparable with those of selective betablockers.
authors.affiliation: Ocná klinika Dérerovej nemocnice, Bratislava.
authors.forename: M
authors.initials: M
authors.lastname: Potocký
authors.forename: E
authors.initials: E
authors.lastname: Vodrázková
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D015784:Betaxolol / Q000627:therapeutic use; D005902:Glaucoma, Open-Angle / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D002040:Levobunolol / Q000627:therapeutic use; D008875:Middle Aged; D013999:Timolol / Q000627:therapeutic use; D014797:Vital Capacity / Q000187:drug effects
chemical_list: D000319:Adrenergic beta-Antagonists; D013999:Timolol; D002040:Levobunolol; D015784:Betaxolol
vernacular_title: Betablokátory v liecbe glaukómu s otvoreným uhlom.