title: Aldose reductase as dihydrodiol dehydrogenase. Naphthoquinone formation by rat lens aldose reductase.
authors.affiliation: Laboratory of Ocular Therapeutics, National Eye Institute, National Institutes of Health, Bethesda, Maryland 20892-1850, USA.
authors.forename: S
authors.initials: S
authors.lastname: Sato
authors.forename: K
authors.initials: K
authors.lastname: Sugiyama
authors.forename: D
authors.initials: D
authors.lastname: Carper
mesh_terms: D000449:Aldehyde Reductase / Q000302:isolation & purification / Q000378:metabolism*; D000818:Animals; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005136:Eye Proteins / Q000302:isolation & purification / Q000378:metabolism*; D005449:Fluorenes / Q000494:pharmacology; D006827:Hydantoins / Q000494:pharmacology; D007093:Imidazoles / Q000494:pharmacology; D048289:Imidazolidines; D007908:Lens, Crystalline / Q000201:enzymology*; D009281:Naphthalenes / Q000494:pharmacology; D009285:Naphthoquinones / Q000378:metabolism*; D010088:Oxidoreductases / Q000302:isolation & purification / Q000378:metabolism*; D010793:Phthalazines / Q000494:pharmacology; D051381:Rats
chemical_list: D004791:Enzyme Inhibitors; D005136:Eye Proteins; D005449:Fluorenes; D006827:Hydantoins; D007093:Imidazoles; D048289:Imidazolidines; D009281:Naphthalenes; D009285:Naphthoquinones; D010793:Phthalazines; C052241:imirestat; C040550:tolrestat; C042829:ponalrestat; D010088:Oxidoreductases; D000449:Aldehyde Reductase; C048338:trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; C026411:sorbinil