title: [A case of anaplastic carcinoma of the thyroid. Clinico-pathological and therapeutic aspects and review of the literature].
abstract: A case of anaplastic carcinoma of the thyroid observed in a 72-year-old female patient, admitted with previous diagnosis of Riedel's thyroiditis, is reported. Clinicopathologic features and management of this rare neoplasm are discussed and Literature is reviewed. Anaplastic cancer is a locally and systemically aggressive histologic type, occurring more frequently in older patients and in those with a history of benign and/or malignant thyroid disease. Because long-term survival was seen most commonly in well-localized anaplastic tumors, a more aggressive approach to thyroid lesions, especially in the elderly, may be warranted to improve early diagnosis and effectiveness of therapy of this nearly always lethal neoplasm. Although patients can rarely be cured, efforts should be made to control the disease locally by combined treatment including surgery and radiochemotherapy, which is found to be, at times, a national palliative therapeutic approach despite patient's advanced age.
authors.affiliation: Cattedra di Chirurgia Geriatrica I, Università degli Studi La Sapienza Roma.
authors.forename: G
authors.initials: G
authors.lastname: Martino
authors.forename: S
authors.initials: S
authors.lastname: Cariati
authors.forename: G
authors.initials: G
authors.lastname: Pascarella
authors.forename: A L
authors.initials: AL
authors.lastname: Russo
authors.forename: U
authors.initials: U
authors.lastname: Elmore
authors.forename: M
authors.initials: M
authors.lastname: Calvitti
authors.forename: M
authors.initials: M
authors.lastname: Onorato
authors.forename: P
authors.initials: P
authors.lastname: Pontone
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D002277:Carcinoma / Q000473:pathology / Q000532:radiotherapy; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D011879:Radiotherapy Dosage; D013961:Thyroid Gland / Q000473:pathology; D013964:Thyroid Neoplasms / Q000473:pathology / Q000532:radiotherapy; D014057:Tomography, X-Ray Computed
vernacular_title: Un caso di carcinoma anaplastico della tiroide. Aspetti clinico-patologici, terapeutici e revisione della Letteratura.