[Effects of hyperbaric oxygenation on free radical oxidation and antioxidant system of blood in the newborn who had acute hypoxia at birth].
Hyperbaric oxygenation (HBO) was added to the complex of intensive care for 14 full-term newborns born asphyxiated and with cerebral circulation disorders of the I-II degree. Study of the antioxidant enzymatic system and free-radical oxidation by chemiluminescence showed no changes in superoxide dismutase and catalase and a 1.6-2 times increase in the activity of glutathione peroxidase, on the one hand, and an appreciable decrease of free radical processes, on the other. This permitted a conclusion about the absence of toxic effects during HBO and on its membrane-stabilizing action.
Baĭborodov
B D
BD
Savel'eva
T V
TV
Prokopenko
V M
VM
Evsiukova
I I
II
Arutiunian
A V
AV
D000975:Antioxidants; D001238:Asphyxia Neonatorum / Q000097:blood / Q000628:therapy*; D002374:Catalase / Q000097:blood; D003422:Critical Care; D005609:Free Radicals; D006801:Humans; D006931:Hyperbaric Oxygenation; D007231:Infant, Newborn; D008163:Luminescent Measurements; D013482:Superoxide Dismutase / Q000097:blood
D000975:Antioxidants; D005609:Free Radicals; D002374:Catalase; D013482:Superoxide Dismutase
Vliianie giperbaricheskoĭ oksigenatsii na svobodnoradikal'noe okislenie i antioksidantnuiu sistemu krovi novorozhdennykh deteĭ, perenesshikh ostruiu gipoksiiu pri rozhdenii.