Neurotrophins: the yin and yang of nerve growth factor.
In the fifty years since its discovery, a substantial body of work has established that nerve growth factor plays a key role in promoting the survival of neurons during development; the recent demonstration that it can also promote cell death therefore comes as a surprise.
Davies
A M
AM
School of Biological and Medical Sciences, University of St. Andrews, St. Andrews, Fife KY16 9TS, Scotland, UK. amd2@st-and.ac-uk
D000818:Animals; D017209:Apoptosis / Q000502:physiology; D051379:Mice; D009414:Nerve Growth Factors / Q000502:physiology*; D020800:Receptor, Nerve Growth Factor; D017475:Receptors, Nerve Growth Factor / Q000502:physiology
D009414:Nerve Growth Factors; D020800:Receptor, Nerve Growth Factor; D017475:Receptors, Nerve Growth Factor