title: Studies on arylfuran derivatives-Part VI. Synthesis, characterization and antibacterial activities of some 6-(5-aryl-2-furyl)-1,2,4-triazolo [3,4-b]-1,3,4-thiadiazoles and 6-(5-nitro-2-furyl)-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazoles.
abstract: A series of 4-[5-aryl-2-furfurylidene]amino-3-mercapto-5-substituted-1,2,4-tri azoles and 4-[5-Nitro-2-furfurylidene]amino-3-mercapto-5-substituted-1,2,4-tr iazoles have been synthesized and were converted into 1,2,4-triazolo [3,4-b]-1,3,4-thiadiazoles. These triazolothiadiazoles are also synthesized by an alternative method in better yields employing arylfuroic acids and s-triazoles in the presence of phosphorus oxychloride. The newly synthesized compounds are screened for their antibacterial properties.
authors.affiliation: Department of Post-Graduate Studies and Research in Chemistry, Mangalore University, India.
authors.forename: B S
authors.initials: BS
authors.lastname: Holla
authors.forename: M K
authors.initials: MK
authors.lastname: Shivananda
authors.forename: P M
authors.initials: PM
authors.lastname: Akberali
authors.forename: S
authors.initials: S
authors.lastname: Baliga
authors.forename: S
authors.initials: S
authors.lastname: Safeer
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D008826:Microbial Sensitivity Tests; D013830:Thiadiazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D014230:Triazoles / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D013830:Thiadiazoles; D014230:Triazoles