[Immunophenotyping in the differential diagnosis of malignant non-hodgkin's lymphomas].
Non-Hodgkin's malignant lymphoma was diagnosed in 66 patients by immunophenotype technique using a batch of 13 Russian-isolated monoclonal antibodies which help identify antigens of T- and B-lymphocyte surface membranes. Polyclonal light chains of immunoglobulins and T- and B-cell antigens were identified in the course of histological examination of biopsy material sampled from hyperplasia lymphoid tissue. B-cell lymphomas revealed monoclonal light chains of immunoglobulins and positive B-cell antigens. T-cell tumors had mostly T-cell antigens and no light chains of immunoglobulins. Neither common leukocyte antigen, nor panT- or panB-cell antigens were found in 7 cases of cancer metastasis to lymph nodes.
Dzembak
T M
TM
Gurkalo
V K
VK
Gershanovich
M L
ML
D000911:Antibodies, Monoclonal; D003937:Diagnosis, Differential; D006801:Humans; D016130:Immunophenotyping; D016393:Lymphoma, B-Cell / Q000175:diagnosis; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis* / Q000235:genetics / Q000276:immunology; D016399:Lymphoma, T-Cell / Q000175:diagnosis; D013601:T-Lymphocytes / Q000276:immunology
D000911:Antibodies, Monoclonal
Immunofenotipirovanie v differentsial'noĭ diagnostike nekhodzhkinskikh zlokachestvennykh limfom.