The physical and genetic map surrounding the Lyst gene on mouse chromosome 13.
During the recent cloning of the mouse Lyst gene we developed both a high-resolution genetic map and a complete YAC and BAC contig of the Lyst critical region on mouse Chromosome 13. We also report the mapping of the human homologue of the mouse Lyst gene (LYST) to 1q43. These data are consistent with LYST being the gene for the human Chediak-Higashi Syndrome and strengthen the synteny relationship between MMU13 and human 1q43.
Misumi
D J
DJ
Millennium Pharmaceuticals, Inc., Cambridge, Massachusetts 02139, USA.
Nagle
D L
DL
McGrail
S H
SH
Dussault
B J
BJ
Smutko
J S
JS
Chen
H
H
Charlat
O
O
Duyk
G M
GM
Ebeling
C
C
Baldini
L
L
Carlson
G A
GA
Moore
K J
KJ
D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D018076:DNA, Complementary; D005260:Female; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D008969:Molecular Sequence Data; D011506:Proteins / Q000235:genetics*; D033921:Vesicular Transport Proteins
D018076:DNA, Complementary; D047908:Intracellular Signaling Peptides and Proteins; C102161:LYST protein, human; C491133:Lyst protein, mouse; D011506:Proteins; D033921:Vesicular Transport Proteins