title: Comparison of two plate-haptic intraocular lenses in a rabbit model.
abstract: OBJECTIVE
  To compare the presence of fibrosis through footplate positioning holes in two different silicone intraocular lenses (IOLs) following phacoemulsification with IOL implantation.
  
  
  METHODS
  Moran Eye Center, University of Utah, Salt Lake City.
  
  
  METHODS
  Twelve New Zealand white rabbits had phacoemulsification with placement of a control silicone IOL in one eye and a study IOL with a larger positioning hole in the opposite eye. The amount of force required to remove the IOLs from the capsular bag was analyzed at 3 and 6 weeks postoperatively.
  
  
  RESULTS
  The force necessary to remove the study lens with the larger positioning holes was statistically significantly greater at both 3 and 6 weeks than that necessary to remove the control lenses. Capsular fibrosis with proliferative lens cortical material through the larger positioning holes was also documented grossly using the Miyake technique.
  
  
  CONCLUSIONS
  The larger footplate positioning holes in the study silicone IOL significantly increased capsular bag fixation in the rabbit model following phacoemulsification and IOL implantation.
authors.affiliation: Department of Ophthalmology, University of Utah, Salt Lake City 84132, USA.
authors.forename: N
authors.initials: N
authors.lastname: Mamalis
authors.forename: O
authors.initials: O
authors.lastname: Omar
authors.forename: J
authors.initials: J
authors.lastname: Veiga
authors.forename: D
authors.initials: D
authors.lastname: Tanner
authors.forename: A
authors.initials: A
authors.lastname: Pirayesh
authors.forename: D S
authors.initials: DS
authors.lastname: Fernquist
mesh_terms: D000818:Animals; D002455:Cell Division; D004195:Disease Models, Animal; D005355:Fibrosis / Q000209:etiology / Q000473:pathology; D005500:Follow-Up Studies; D007903:Lens Capsule, Crystalline / Q000473:pathology / Q000601:surgery; D007910:Lenses, Intraocular / Q000009:adverse effects; D018918:Phacoemulsification / Q000379:methods; D011183:Postoperative Complications / Q000209:etiology / Q000473:pathology*; D011474:Prosthesis Design; D011817:Rabbits; D012826:Silicone Elastomers / Q000009:adverse effects
chemical_list: D012826:Silicone Elastomers