Pre leukemic granulocytic sarcoma of vagina. A case report with review of literature.
Granulocytic sarcoma is an extramedullary tumor of malignant granulocytic progenitor cells, that may precede the onset of acute myeloid leukemia or appear during the leukemic manifestation or blastic crisis of chronic myeloproliferative disorders. We describe a case of granulocytic sarcoma of vagina in a 27 year old woman treated with local radiotherapy. After seven months of follow up she developed acute myeloid leukemia. The case has been presented in view of its rarity and discussed in light of the available literature.
Lakshminarasimhan
S
S
Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bangalore, India.
Doval
D C
DC
Rajashekhar
U
U
Mukherjee
G
G
Kannan
V
V
Devi
L
L
Bapsy
P P
PP
D000328:Adult; D001706:Biopsy; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000209:etiology*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic; D012509:Sarcoma / Q000150:complications* / Q000532:radiotherapy; D014625:Vaginal Neoplasms / Q000150:complications* / Q000473:pathology / Q000532:radiotherapy