title: Capillary biomolecular separations.
abstract: This article summarizes the recent advances in microcolumn separations of biopolymers. Microcolumn liquid chromatography is primarily emphasized for its role as a micropreparative and fractionation tool, whereas high-performance capillary electrophoresis is demonstrated as a highly efficient technique for final analyses. Following a brief discussion of new trends in instrumentation, the recent applications of capillary techniques to proteins, DNA and glycoconjugates are reviewed.
authors.affiliation: Department of Chemistry, Indiana University, Bloomington 47405, USA.
authors.forename: M V
authors.initials: MV
authors.lastname: Novotny
mesh_terms: D002853:Chromatography, Liquid / Q000295:instrumentation / Q000379:methods* / Q000639:trends; D004247:DNA / Q000302:isolation & purification; D019075:Electrophoresis, Capillary / Q000295:instrumentation / Q000379:methods* / Q000639:trends; D006001:Glycoconjugates / Q000302:isolation & purification; D008832:Microchemistry; D011506:Proteins / Q000302:isolation & purification
chemical_list: D006001:Glycoconjugates; D011506:Proteins; D004247:DNA