Clinical and radiographic stabilization of intracranial glioblastoma. Report of a case treated after surgery with tamoxifen.
We report the case of a patient with a left temporal-parietal glioblastoma treated with subtotal surgical excision, radiotherapy and chemotherapy, with a single intravenous administration of carboplatin and continuous oral administration of tamoxifen (40 mg/daily). Two years after the patient presents a stabilization of clinical and CT picture. We discute the possible role of tamoxifen in prolonging the survival of selected patients with intracranial high-grade glioma.
Mastronardi
L
L
Civilian Hospital of Terni, Italy.
Farah
J O
JO
Puzzilli
F
F
Qasho
R
R
Lunardi
P
P
D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000601:surgery*; D005909:Glioblastoma / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011859:Radiography; D013629:Tamoxifen / Q000627:therapeutic use*; D013702:Temporal Lobe / Q000473:pathology*
D013629:Tamoxifen