Contact sensitization to 6 alpha-methylprednisolone aceponate.
Increasing attention has been focused on contact sensitization to topical corticosteroids in the past several years. In most cases, allergy to topical corticosteroids occurs in patients with long-lasting eczematous diseases. Cross-allergy between topical corticosteroid molecules is very common, and four groups of cross-reacting molecules have been recognized. In this report, we describe a girl with atopic dermatitis and sensitized to hydrocortisone-17-butyrate who became sensitized to 6 alpha-methylprednisolone aceponate. Cross-sensitization between the two molecules is suggested.
Balato
N
N
Clinica Dermatologica, Università di Napoli, Federico II, Italy.
Patruno
C
C
Lembo
G
G
Cuccurullo
F M
FM
Ayala
F
F
D000287:Administration, Topical; D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D003429:Cross Reactions; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000009:adverse effects / Q000031:analogs & derivatives; D008775:Methylprednisolone / Q000009:adverse effects / Q000031:analogs & derivatives*
D000893:Anti-Inflammatory Agents; C007975:hydrocortisone-17-butyrate; C078007:methylprednisolone aceponate; D006854:Hydrocortisone; D008775:Methylprednisolone