[Results of 25-year pheochromocytoma treatment in the Groningen Academic Hospital].
OBJECTIVE
To evaluate 25 years' experience with the localisation techniques, operative management and results of treatment for phaeochromocytoma.


METHODS
Retrospective


METHODS
Groningen University Hospital, the Netherlands.


METHODS
Localisation results, per- and postoperative morbidity, mortality and treatment results were evaluated in all 59 patients treated for phaeochromocytoma in the period 1970-1995; 41 patients underwent unilateral adrenalectomy, 18 underwent bilateral adrenalectomy.


RESULTS
From the introduction of MIBG scintigraphy all tumour sites were correctly diagnosed preoperatively. The transabdominal operation lead to considerable morbidity and minimal mortality. All MEN type 2 patients (n = 5) treated with unilateral adrenalectomy developed phaeochromocytoma in the contralateral gland and needed total adrenalectomy 7 to 14 years after the initial operation.


CONCLUSIONS
A retroperitoneal approach in surgical treatment of phaeochromocytoma is to be preferred. In MEN type 2 patients bilateral adrenalectomy is still mandatory.
de Graaf
J S
JS
Academisch Ziekenhuis, afd. Chirurgie, Groningen.
Nieweg
O E
OE
Oosterkamp
A E
AE
Zwierstra
R P
RP
D000293:Adolescent; D000310:Adrenal Gland Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D000315:Adrenalectomy / Q000379:methods; D000328:Adult; D000368:Aged; D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018813:Multiple Endocrine Neoplasia Type 2a / Q000175:diagnosis / Q000601:surgery; D010673:Pheochromocytoma / Q000175:diagnosis* / Q000601:surgery*; D012189:Retrospective Studies
Resultaten van 25 jaar feochromocytoombehandeling in het Academisch Ziekenhuis Groningen.