title: [Analysis of risk factors in patients undergoing closed heart mitral commissurotomy].
abstract: The aim of this study was to analyse the risk factors in patients undergoing closed heart commissurotomy (CHC). From 1956 to 1978 a total of 630 patients with severe mitral stenosis underwent CHC at this Institute. The study was performed on a sample of 100 patients. Follow-up was performed using data taken from the Institute archives, questionnaires sent to the doctors in charge, telephone interviews or visits to outpatient clinics by the Institute's medical staff. The mortality rate 30 days after surgery was 2.9%. Re-CHC was necessary in 11 patients after a mean interval of 7.2 years. The overall probability of survival was 83%, 71%, 48% an 33% respectively at 10, 20, 30 and 40 years. Survival free from mitral re-operation at 10, 20, 30 and 40 years was 76%, 39%, 29% and 11% respectively. The probability of incidence for central and peripheral thromboembolism was 38%, 26%, 11% and 4% at 10, 20, 30 and 40 years. Mitral valve replacement surgery (MVR) was performed in a total of 64 patients. Operative mortality was 0.6% (1 patient). The mean duration of follow-up in patients undergoing post-CHC MVR was 10 years. The probability os survival in overall terms and free of cardiac decompensation was 79 and 53% respectively. From this study it is clear the CHC is a surgical procedure that offers excellent long-term results with a low incidence od thromboembolic events, very low costs and a good quality of life. CHC currently represents a valid alternative o mitral valve replacement in selected patients.
authors.affiliation: Istituto di Chirurgia del Cuore e dei Grossi Vasi, Università degli Studi di Roma La Sapienza, Roma.
authors.forename: G
authors.initials: G
authors.lastname: Speziale
authors.forename: K
authors.initials: K
authors.lastname: Fattouch
authors.forename: A
authors.initials: A
authors.lastname: Giovannelli
authors.forename: O
authors.initials: O
authors.lastname: Spadaro
authors.forename: C
authors.initials: C
authors.lastname: Lavalle
authors.forename: G
authors.initials: G
authors.lastname: Ruvolo
authors.forename: B
authors.initials: B
authors.lastname: Marino
mesh_terms: D005500:Follow-Up Studies; D006801:Humans; D008946:Mitral Valve Stenosis / Q000601:surgery*; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D016019:Survival Analysis
vernacular_title: Analisi dei fattori di rischio in pazienti sottoposti a commissurotomia mitralica a cuore chiuso.