Parenteral ciprofloxacin in persistent diarrhoea in children.
In a controlled trial of 30 cases of persistent diarrhoea in infants, ciprofloxacin was used parenterally for systemic antibiotic therapy. Group A cases (15 in number) were treated with parenteral ciprofloxacin and group B control cases (remaining 15) were treated with parenteral ampicillin and chloramphenicol or ampicillin/amikacin along with treatment of dehydration and malnutrition. All group A cases had excellent response and 9 infants of group B had no response up to day 4. After stopping all other drugs and with parenteral ciprofloxacin they responded favourably. Follow-up of all the cases was done regularly every 2 weeks for 6 months after discharge. No toxicity of ciprofloxacin was noted.
Ghosh
G
G
Institute of Child Health, Calcutta.
Chakraborty
S
S
Ray
J
J
Mukherjee
S K
SK
D000900:Anti-Bacterial Agents; D001424:Bacterial Infections / Q000188:drug therapy*; D002939:Ciprofloxacin / Q000008:administration & dosage*; D003968:Diarrhea, Infantile / Q000188:drug therapy*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007194:India; D007223:Infant; D007231:Infant, Newborn; D007262:Infusions, Intravenous; D008297:Male
D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin