Spontaneous neurological improvement in anti-Hu associated encephalomyelitis.
Symptoms of anti-Hu associated paraneoplastic encephalomyelitis (PEM) and sensory neuropathy (PSN) are usually severe and irreversible. Two patients are reported whose symptoms improved spontaneously, and in one of them they resolved after resection of an inflammatory lesion of the lung. Spontaneous neurological improvement, although rare, should be considered in the evaluation of therapies for PEM/PSN.
Byrne
T
T
Department of Neurology, Yale University School of Medicine, New Haven, CT, USA.
Mason
W P
WP
Posner
J B
JB
Dalmau
J
J
D000368:Aged; D051959:ELAV Proteins; D004679:Encephalomyelitis / Q000150:complications / Q000175:diagnosis / Q000276:immunology*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000175:diagnosis; D008875:Middle Aged; D009419:Nerve Tissue Proteins; D016601:RNA-Binding Proteins / Q000276:immunology*; D012075:Remission, Spontaneous
D051959:ELAV Proteins; D009419:Nerve Tissue Proteins; D016601:RNA-Binding Proteins