Proteus syndrome: new findings in seven patients.
Seven children with Proteus syndrome (PS) are reported. The majority of clinical findings coincide with what is reported in the literature. New findings were blue sclerae, telecanthus, epiblepharon, endotropy, hemimegaly of the optic nerve, occipital dysmyelination and compression of the corpus callosum, craneosynostosis, decalcification and thinning of the cortical layer of long bones, and talipes equinus. The clinical findings, possible etiology, differential diagnosis, and treatment of PS are discussed.
del Rosario Barona-Mazuera
M
M
Department of Pediatric Dermatology, National Institute of Pediatrics, Mexico City.
Hidalgo-Galván
L R
LR
de la Luz Orozco-Covarrubias
Durán-McKinster
C
C
Tamayo-Sánchez
L
L
Ruiz-Maldonado
R
R
D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D016715:Proteus Syndrome / Q000175:diagnosis / Q000473:pathology