title: [Use of pefloxacin in the treatment of infected burn wounds].
abstract: The efficacy of a home-made pefloxacin was estimated in clinico-laboratory trials including 25 patients with wound infection. The fluoroquinolone was used in a dose of 400 mg administered orally twice a day for 4-16 days. Good and satisfactory results were stated in 24 patients (96 per cent). The isolates from the patients were mainly susceptible to the drug (86.2 per cent). The bacteriological efficacy amounted to 92 per cent. No side effects to the use of pefloxacin were observed.
authors.forename: V P
authors.initials: VP
authors.lastname: Iakovlev
authors.forename: A A
authors.initials: AA
authors.lastname: Alekseev
authors.forename: M G
authors.initials: MG
authors.lastname: Krutikov
authors.forename: I A
authors.initials: IA
authors.lastname: Grishina
authors.forename: G N
authors.initials: GN
authors.lastname: Izotova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000890:Anti-Infective Agents / Q000493:pharmacokinetics / Q000627:therapeutic use*; D002056:Burns / Q000150:complications* / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015366:Pefloxacin / Q000009:adverse effects / Q000493:pharmacokinetics / Q000627:therapeutic use*; D016896:Treatment Outcome; D014946:Wound Infection / Q000188:drug therapy* / Q000378:metabolism / Q000382:microbiology
chemical_list: D000890:Anti-Infective Agents; D015366:Pefloxacin
vernacular_title: Primenenie pefloksatsina dlia lecheniia infitsirovannykh ozhogovykh ran.