title: [Comparative study of HELISAL T.M. RAPID BLOOD and ELISA, JATROX and pathologic anatomy in the diagnosis of Helicobacter pylori infection].
abstract: OBJECTIVE
  To assess the usefulness of HELISAL in the diagnosis of Helicobacter pylori infection by comparing it with ELISA, JATROX and histopathologic findings.
  
  
  METHODS
  Randomized prospective study.
  
  
  METHODS
  Sixty-one patients, thirty-three males and twenty-eight females, 18-73 years old, submitted to esophagogastroduodenoscopy.
  
  
  RESULTS
  The sensitivity of HELISAL when compared to ELISA test was 60.8%, the specificity 73.3%, the positive predictive value 87.5%, the negative predictive value 37.9%, and the kappa index 0.26. When compared to histopathologic test: sensitivity 60.9%, specificity 65%, positive predictive value 78.1%, negative predictive value 44.7%, kappa 0.28. When compared to JATROX, sensitivity 57.7%, specificity 62.5%, positive predictive value 81.2%, negative predictive value 34.4%, kappa 0.21.
  
  
  CONCLUSIONS
  The sensitivity of HELISAL test is lower than that of other compared tests, and the negative predictive value is very low. The specificity and the positive predictive value are higher than the sensitivity. The kappa index shows a very low concordance.
authors.affiliation: Servicio de Aparato Digestivo, Hospital Regional Carlos Haya, Málaga.
authors.forename: J
authors.initials: J
authors.lastname: Huelin
authors.forename: S
authors.initials: S
authors.lastname: Sánchez-Galdón
authors.forename: A
authors.initials: A
authors.lastname: Cárdenas
authors.forename: J
authors.initials: J
authors.lastname: Ibáñez
authors.forename: P
authors.initials: P
authors.lastname: España
authors.forename: J
authors.initials: J
authors.lastname: De la Cruz
authors.forename: M
authors.initials: M
authors.lastname: Jiménez
authors.forename: B
authors.initials: B
authors.lastname: Ferreiro
authors.forename: J M
authors.initials: JM
authors.lastname: Lozano
authors.forename: G
authors.initials: G
authors.lastname: Maldonado
mesh_terms: D000328:Adult; D000368:Aged; D015373:Bacterial Typing Techniques; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016481:Helicobacter Infections / Q000097:blood / Q000175:diagnosis* / Q000473:pathology; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012680:Sensitivity and Specificity
vernacular_title: Estudio comparativo entre HELISAL T.M. RAPID BLOOD y ELISA, JATROX y anatomia patológica en el diagnostico de la infección por Helicobacter pylori.