title: Magnetic resonance imaging of temperature changes during interstitial microwave heating: a phantom study.
abstract: Changes in magnetic resonance (MR) signals during interstitial microwave heating are reported, and correlated with simultaneously acquired temperature readings from three fiber-optic probes implanted in a polyacrylamide gel phantom. The heating by a MR-compatible microwave antenna did not interfere with simultaneous MR image data acquisition. MR phase-difference images were obtained using a fast two-dimensional-gradient echo sequence. From these images the temperature-sensitive resonant frequency of the 1H nuclei was found to decrease approximately by 0.008 ppm/ degree C. The method and results presented here demonstrate that noninvasive MR-temperature imaging can be performed simultaneously with interstitial microwave thermal treatment.
authors.affiliation: Ontario Cancer Institute/Princess Margaret Hospital, University of Toronto, Canada.
authors.forename: I A
authors.initials: IA
authors.lastname: Vitkin
authors.forename: J A
authors.initials: JA
authors.lastname: Moriarty
authors.forename: R D
authors.initials: RD
authors.lastname: Peters
authors.forename: M C
authors.initials: MC
authors.lastname: Kolios
authors.forename: A S
authors.initials: AS
authors.lastname: Gladman
authors.forename: J C
authors.initials: JC
authors.lastname: Chen
authors.forename: R S
authors.initials: RS
authors.lastname: Hinks
authors.forename: J W
authors.initials: JW
authors.lastname: Hunt
authors.forename: B C
authors.initials: BC
authors.lastname: Wilson
authors.forename: A C
authors.initials: AC
authors.lastname: Easty
authors.forename: M J
authors.initials: MJ
authors.lastname: Bronskill
authors.forename: W
authors.initials: W
authors.lastname: Kucharczyk
authors.forename: M D
authors.initials: MD
authors.lastname: Sherar
authors.forename: R M
authors.initials: RM
authors.lastname: Henkelman
mesh_terms: D055592:Biophysical Phenomena; D001703:Biophysics; D005336:Fiber Optic Technology; D006979:Hyperthermia, Induced; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D008872:Microwaves / Q000627:therapeutic use; D055100:Optical Fibers; D019047:Phantoms, Imaging; D013696:Temperature