[Coagulation in hemodialysis].
The authors have evaluated the behaviour of protein C activity, factor X and factor VII coagulant activity, and serum lipoprotein(a) before and after haemodialytic treatment in the plasma of patients on maintenance haemodialysis. The plasma level of protein C activity, depressed before haemodialysis, significantly increased during the course of haemodialysis; factor X and factor VII increased as well despite heparinization; serum lipoprotein(a) was abnormally elevated before haemodialysis and did not change after haemodialysis. In vitro incubation (30' at 37 degrees C) of uremic and healthy blood samples resulted in a decrease of serum lipoprotein(a) concentration. After heparin addition (final concentration 0.5 U/ml) lipoprotein(a) became higher in uremic blood only.
Camici
M
M
Divisione di Nefrologia, Ospedale Santa Chiard, Università degli Studi, Pisa.
Evangelisti
L
L
Balestri
P
P
Cioni
L
L
Rindi
P
P
Sagripanti
A
A
Meriggioli
M
M
Giordani
R
R
D000328:Adult; D000368:Aged; D001777:Blood Coagulation; D005167:Factor VII / Q000502:physiology*; D005170:Factor X / Q000502:physiology*; D005260:Female; D006801:Humans; D017270:Lipoprotein(a) / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011486:Protein C / Q000502:physiology*; D006435:Renal Dialysis
D017270:Lipoprotein(a); D011486:Protein C; D005167:Factor VII; D005170:Factor X
Coagulazione in emodialisi.