title: Malignancy in chronic osteomyelitis sinus. Report of three cases.
abstract: Three cases of squamous cell carcinoma in a chronic osteomyelitis sinus is reported. These tumours are usually managed by amputation alone. One of our patient had a histologically invasive and keratinising tumour who died after amputation. The other two cases are still surviving, one even without any treatment. We believe that in patients with histologically undifferentiated and invasive tumours aggressive mode of treatment should be carried out by way of amputation, regional lymph node clearance and a short course of chemotherapy/radiotherapy.
authors.affiliation: King Fahd University Hospital, Dammam.
authors.forename: M
authors.initials: M
authors.lastname: Sadat-Ali
authors.forename: S S
authors.initials: SS
authors.lastname: Geeranavar
mesh_terms: D000328:Adult; D000368:Aged; D000671:Amputation, Surgical; D001859:Bone Neoplasms / Q000209:etiology* / Q000473:pathology; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000473:pathology / Q000556:secondary; D002908:Chronic Disease; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005360:Fibula; D006801:Humans; D008175:Lung Neoplasms / Q000556:secondary; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000150:complications*; D013977:Tibia