A case of tuberous sclerosis with a giant angiofibroma.
This is a case study of tuberous sclerosis with unusually large facial angiofibromas. The patient had other intense skin manifestations. Histological findings in the angiofibroma included large and glial-appearing cells specific for this disease. Karyotype analysis revealed a translocation of chromosome (12q-, 15q+).
Wataya-Kaneda
M
M
Department of Dermatology, Osaka University School of Medicine, Suita, Japan.
Yano
K
K
Hosokawa
K
K
Yoshikawa
K
K
D000328:Adult; D018322:Angiofibroma / Q000150:complications* / Q000235:genetics / Q000473:pathology; D002881:Chromosomes, Human, Pair 12 / Q000235:genetics; D002884:Chromosomes, Human, Pair 15 / Q000235:genetics; D005153:Facial Neoplasms / Q000150:complications* / Q000235:genetics / Q000473:pathology; D005260:Female; D006801:Humans; D007621:Karyotyping; D012878:Skin Neoplasms / Q000150:complications* / Q000235:genetics / Q000473:pathology; D014178:Translocation, Genetic / Q000235:genetics; D014402:Tuberous Sclerosis / Q000150:complications* / Q000473:pathology