title: High resolution EEG: a new model-dependent spatial deblurring method using a realistically-shaped MR-constructed subject's head model.
abstract: This paper presents a new model-dependent method for the spatial deblurring of scalp-recorded EEG potentials based on boundary-element and cortical imaging techniques. This model-dependent spatial deblurring (MDSD) method used MR images for the reconstruction of the subject's head model, and a layer of 364 radially-oriented equivalent current dipoles as a source model. The validation of the MDSD method was performed on simulated potential distributions generated from equivalent dipoles oriented radially, obliquely, and tangentially to the head surface. Furthermore, this method was used to localize neocortical sources of human movement-related and somatosensory-evoked potentials. It was shown that the new MDSD method improved markedly the spatial resolution of the simulated surface potentials and scalp-recorded event-related potentials. The spatial information content of the scalp-recorded EEG potentials increased progressively by increasing the spatial sampling from 28 to 128 channels. These results indicate that the new method could be satisfactorily used for high resolution EEG studies.
authors.affiliation: Institute of Human Physiology, University of Rome La Sapienza, Italy. babilonif@axrma.uniromal.it
authors.forename: F
authors.initials: F
authors.lastname: Babiloni
authors.forename: C
authors.initials: C
authors.lastname: Babiloni
authors.forename: F
authors.initials: F
authors.lastname: Carducci
authors.forename: L
authors.initials: L
authors.lastname: Fattorini
authors.forename: C
authors.initials: C
authors.lastname: Anello
authors.forename: P
authors.initials: P
authors.lastname: Onorati
authors.forename: A
authors.initials: A
authors.lastname: Urbano
mesh_terms: D001921:Brain / Q000502:physiology*; D004569:Electroencephalography; D006801:Humans; D008959:Models, Neurological