NSAIDs revisited: selection, monitoring, and safe use.
Although nonsteroidal anti-inflammatory drugs (NSAIDs) are effective analgesic and anti-inflammatory agents, they may have adverse effects on the gastrointestinal, hepatic, renal, pulmonary, and platelet aggregation systems in susceptible patients. Careful consideration of the risks and benefits, judicious dosing, and careful monitoring by the primary care physician are therefore essential. The authors of this article review both the therapeutic and adverse effects of NSAIDs and provide suggestions for safe clinical use.
Amadio
P
P
Jefferson Medical College of Thomas Jefferson University, Philadelphia, USA.
Cummings
D M
DM
Amadio
P B
PB
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects / Q000494:pharmacology* / Q000627:therapeutic use*; D004064:Digestive System / Q000187:drug effects; D006801:Humans; D010146:Pain / Q000188:drug therapy*
D000894:Anti-Inflammatory Agents, Non-Steroidal