title: Results of a survey to determine whether Neospora is a significant cause of ovine abortion in England and Wales.
abstract: Between January and April 1995, the brains and hearts of 281 aborted lambs derived from 209 submissions to veterinary investigation centres in England and Wales were examined histologically. One-hundred-and-seventy-nine samples of fetal pleural fluid from these lambs and 141 from lambs not examined histologically were examined for antibodies to Neospora by an indirect fluorescent antibody test. Non-suppurative myocarditis and encephalitis were present in nine lambs. Immunocytochemistry using antisera against Neospora caninum and Sarcocystis species resulted in no labelling but anti-sera to Toxoplasma gondii revealed labelled organisms in four lambs. No significant antibody titres against Neospora were detected in any of the samples of fetal pleural fluid. These results suggest that Neospora infection is not associated with significant numbers of abortions in sheep in England and Wales.
authors.affiliation: Veterinary Investigation Centre, Johnstown, Carmarthen.
authors.forename: A
authors.initials: A
authors.lastname: Otter
authors.forename: B W
authors.initials: BW
authors.lastname: Wilson
authors.forename: S F
authors.initials: SF
authors.lastname: Scholes
authors.forename: M
authors.initials: M
authors.lastname: Jeffrey
authors.forename: B
authors.initials: B
authors.lastname: Helmick
authors.forename: A J
authors.initials: AJ
authors.lastname: Trees
mesh_terms: D000034:Abortion, Veterinary / Q000453:epidemiology / Q000469:parasitology* / Q000473:pathology; D000818:Animals; D000913:Antibodies, Protozoan / Q000302:isolation & purification; D003048:Coccidiosis / Q000150:complications / Q000453:epidemiology / Q000662:veterinary*; D004739:England / Q000453:epidemiology; D005260:Female; D018688:Neospora / Q000276:immunology*; D010920:Placenta / Q000382:microbiology; D011247:Pregnancy; D012756:Sheep; D014122:Toxoplasma / Q000302:isolation & purification; D014852:Wales / Q000453:epidemiology
chemical_list: D000913:Antibodies, Protozoan