Anticoagulant therapy during successful pregnancy and delivery in a Kawasaki disease patient with coronary aneurysm--a case report.
Thirty-one-year-old woman with Kawasaki disease wanted a child. She had a large coronary aneurysm on the left main coronary artery and complete obstruction of the right coronary artery, but there was no sign of ischemia. Heparin anticoagulant therapy was begun 8 weeks after the onset of pregnancy. The activated partial thromboplastin time (APTT) was successfully maintained at 1.5 to 2.0 times normal value during pregnancy and puerperium. There were no thromboembolic complications during pregnancy or after an uneventful cesarean delivery. The neonate was healthy.
Arakawa
K
K
Department of Internal Medicine I, National Defense Medical College, Tokorozawa, Japan.
Akita
T
T
Nishizawa
K
K
Kurita
A
A
Nakamura
H
H
Yoshida
T
T
Kuroda
K
K
Nagata
I
I
D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use*; D003323:Coronary Aneurysm / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D017023:Coronary Angiography; D005260:Female; D006801:Humans; D009080:Mucocutaneous Lymph Node Syndrome / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging / Q000188:drug therapy
D000925:Anticoagulants