title: Psychobiology of premenstrual dysphoric disorder.
abstract: Premenstrual Dysphoric Disorder (PMDD) is the new terminology used in the American Psychiatric Association's Diagnostic and Statistical Manual of Mental Disorders (DSM-IV). It more rigorously defines criteria for what historically has been referred to as premenstrual syndrome (PMS). Based on studies of its phenomenology and course, PMDD was categorized in DSM-IV as a depressive mood disorder. Findings support low serotonin and melatonin metabolism in PMDD compared with healthy control subjects, and an increasing number of rigorous studies report a reduction of symptoms with selective serotonin reuptake inhibitors (SSRIs).
authors.affiliation: University of California, Department of Psychiatry, San Diego, La Jolla 92093, USA.
authors.forename: B L
authors.initials: BL
authors.lastname: Parry
mesh_terms: D000328:Adult; D003863:Depression / Q000503:physiopathology* / Q000628:therapy; D005260:Female; D006801:Humans; D008550:Melatonin / Q000378:metabolism; D008597:Menstrual Cycle / Q000523:psychology*; D009490:Neurosecretory Systems / Q000502:physiology; D011293:Premenstrual Syndrome / Q000503:physiopathology* / Q000628:therapy; D011613:Psychotherapy; D012307:Risk Factors; D012701:Serotonin / Q000378:metabolism; D001615:beta-Endorphin / Q000378:metabolism
chemical_list: D012701:Serotonin; D001615:beta-Endorphin; D008550:Melatonin