title: Anaesthesia for insertion of ear tubes in children: comparison of propofol, thiopentone and halothane.
abstract: To determine the quality of anaesthesia and speed of recovery after propofol anaesthesia for myringotomy in children, 100 children 2-12 years were randomized to one of four anaesthetic regimens for induction/maintenance: thiopentone (STP) (5 mg.kg-1)/halothane, propofol (3 mg.kg-1)/halothane, halothane/halothane or propofol (3 mg.kg-1)/propofol bolus (0.5 mg.kg-1 every 3 min (10 mg.kg-1.h-1)). Nitrous oxide (70%) in oxygen (30%) was used to facilitate insertion of an intravenous catheter and was continued throughout the anaesthetic. We found that the incidence of intraoperative movement in response to surgical stimulation was significantly greater in the prop/prop group 32%, compared with the three other groups (P < 0.02). Although some recovery variables (time to response to questions, sit unaided, tolerate oral fluids, and discharge with fluids) were achieved more rapidly by the prop/ prop group than the other three groups, the times to open eyes, obey commands and, most importantly, discharge from recovery without fluids did not differ between the prop/prop and the hal/ hal groups. We conclude that there is little benefit in using propofol as an induction agent alone or in combination with a propofol maintenance anaesthetic for paediatric myringotomy and tube surgery.
authors.affiliation: Department of Anaesthesia, Waikato Hospital, Hamilton, New Zealand.
authors.forename: R D
authors.initials: RD
authors.lastname: Carpenter
authors.forename: N
authors.initials: N
authors.lastname: Sikich
authors.forename: M
authors.initials: M
authors.lastname: Levine
authors.forename: J
authors.initials: J
authors.lastname: Lerman
mesh_terms: D000762:Anesthesia Recovery Period; D000768:Anesthesia, General; D000769:Anesthesia, Inhalation; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D002648:Child; D002675:Child, Preschool; D005260:Female; D006221:Halothane; D006801:Humans; D008297:Male; D008876:Middle Ear Ventilation; D015742:Propofol; D013874:Thiopental
chemical_list: D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D013874:Thiopental; D006221:Halothane; D015742:Propofol