title: Frequency of sickle cell gene in Arabia.
abstract: This study was conducted on the Saudi population from different regions of Saudi Arabia to determine the frequency of sickle cell gene (Hb S). The results revealed that Hb S was present in most of the regions though at significantly variable frequencies. The highest frequency (0.149) was found in Al-Qateef, an eastern province of Saudi Arabia, and the lowest (0.001) were found in the central region. In some areas a close correlation was evident between malaria endemicity and Hb S gene frequency although a low frequency was encountered in some malaria endemic regions.
authors.affiliation: Medical Biochemistry Department, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
authors.forename: M A
authors.initials: MA
authors.lastname: el-Hazmi
authors.forename: A S
authors.initials: AS
authors.lastname: Warsy
mesh_terms: D000755:Anemia, Sickle Cell / Q000235:genetics*; D005787:Gene Frequency; D006451:Hemoglobin, Sickle / Q000235:genetics*; D006720:Homozygote; D006801:Humans; D012529:Saudi Arabia
chemical_list: D006451:Hemoglobin, Sickle