title: Randomization to nutritional intervention at home did not improve postoperative function, fatigue or well-being.
abstract: BACKGROUND
  Postoperative fatigue and deterioration in functional capacity have been correlated to postoperative weight loss. This suggested that nutritional support to enhance the regain of weight might improve upon the convalescence.
  
  
  METHODS
  Patients were allocated randomly at discharge to standard management or to dietary advice and protein-rich supplements for 4 months. The convalescence of 32 patients admitted electively for colorectal surgery and of 21 operated on for acute obstruction or severe peritonitis was studied.
  
  
  RESULTS
  The intervention substantially increased protein intake, gain in body-weight and lean body mass, especially in the legs as shown by dual-energy X-ray absorptiometry. Changes in work capacity, hand grip and pinching strength, fatigue and quality of life were similar in patients in control and intervention groups and had returned to preoperative values 1-2 months after operation, although fatigue was increased at 2-3 months.
  
  
  CONCLUSIONS
  This study did not support the hypothesis that changes in weight were important for the changes in function and fatigue in patients with small to moderate weight loss.
authors.affiliation: Surgical Department L, Aarhus Amtssygehus, University Hospital of Aarhus, Denmark.
authors.forename: M B
authors.initials: MB
authors.lastname: Jensen
authors.forename: I
authors.initials: I
authors.lastname: Hessov
mesh_terms: D001823:Body Composition; D003108:Colonic Diseases / Q000503:physiopathology / Q000601:surgery*; D017558:Elective Surgical Procedures; D002149:Energy Intake; D005221:Fatigue / Q000503:physiopathology / Q000517:prevention & control*; D005260:Female; D005541:Forced Expiratory Volume; D018737:Hand Strength; D006339:Heart Rate; D006801:Humans; D007398:Interpersonal Relations; D007415:Intestinal Obstruction / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D018529:Nutritional Support; D011182:Postoperative Care; D011183:Postoperative Complications / Q000503:physiopathology / Q000517:prevention & control*; D011788:Quality of Life; D012002:Rectal Diseases / Q000503:physiopathology / Q000601:surgery; D014797:Vital Capacity; D015430:Weight Gain