title: Screening of renal artery stenosis: assessment with magnetic resonance angiography at 1.0 T.
abstract: The results of MR angiography at 1.0 T with digital intraarterial angiography in the screening of patients with suspected renal hypertension were compared. In this first phase of the study, 10 volunteers underwent examination with both two-dimensional (2D) with traveling saturation time-of-flight (TOF) magnetic resonance angiography (MRA) with various parameters to develop a protocol for evaluation of the renal arteries. In the second phase, 36 patients with suspected renovascular hypertension underwent both 2D TOF MRA and intraarterial digital angiography to evaluate the clinical value of MRA. The degree of stenosis was graded with a two-point scale. In volunteers, using 2D acquisitions C/N ratios indicated the best flip angle as being 55 degrees (p = .02). MRA showed 100% (70/70) of all main arteries and 86% (6/7) of all accessory renal arteries seen on angiography. MRA had a sensitivity of 94% (15/16) and a specificity of 98% (60/61) for detection of stenoses of greater than 50% present in 14 patients. 2D-TOF MRA at 1.0 T shows promise in the noninvasive diagnosis of patients with suspected renovascular hypertension.
authors.affiliation: Department of Radiology, Hôpital Bichat, Paris, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Laissy
authors.forename: M
authors.initials: M
authors.lastname: Benyounes
authors.forename: O
authors.initials: O
authors.lastname: Limot
authors.forename: A
authors.initials: A
authors.lastname: Cinqualbre
authors.forename: H
authors.initials: H
authors.lastname: Benamer
authors.forename: S
authors.initials: S
authors.lastname: Kenouch
authors.forename: M C
authors.initials: MC
authors.lastname: Henry-Feugeas
authors.forename: B
authors.initials: B
authors.lastname: Falise
authors.forename: S
authors.initials: S
authors.lastname: Chillon
authors.forename: P E
authors.initials: PE
authors.lastname: Valere
authors.forename: E
authors.initials: E
authors.lastname: Schouman-Claeys
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006978:Hypertension, Renovascular / Q000175:diagnosis; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D011856:Radiographic Image Enhancement; D012077:Renal Artery / Q000000981:diagnostic imaging / Q000473:pathology; D012078:Renal Artery Obstruction / Q000175:diagnosis* / Q000000981:diagnostic imaging; D012680:Sensitivity and Specificity