title: Quantitative analysis of voice quality in early glottic laryngeal carcinomas treated with radiotherapy.
abstract: The quality of voice after radiotherapy is generally considered to be better than that after surgery for early glottic (T1a and T1b) carcinomas. Studies concerning voice quality after radiotherapy are scarce, and results have been contradictory concerning actual normalization of voice following therapy. This study was designed to compare several voice parameters of patients successfully treated 1-12 years previously with radiotherapy (5750-7000 cGy) for early glottic carcinoma. Parameters involved an age- and sex-matched control group. Results showed that voice quality following radiotherapy was less than normal for maximum vocal intensity, dynamic vocal intensity range, jitter, and mean fundamental frequency. These findings showed that voice following radiotherapy could not be considered normal.
authors.affiliation: University Hospital VU, Department of Otorhinolaryngology, Head and Neck Surgery, Amsterdam, The Netherlands.
authors.forename: A S
authors.initials: AS
authors.lastname: Dagli
authors.forename: H F
authors.initials: HF
authors.lastname: Mahieu
authors.forename: J M
authors.initials: JM
authors.lastname: Festen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000473:pathology / Q000532:radiotherapy*; D016022:Case-Control Studies; D005260:Female; D005931:Glottis / Q000473:pathology / Q000528:radiation effects*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010699:Phonation / Q000528:radiation effects; D011879:Radiotherapy Dosage; D013060:Speech / Q000528:radiation effects; D014831:Voice / Q000528:radiation effects; D014833:Voice Quality / Q000528:radiation effects*