title: Peritoneal dialysis for acute renal failure in infants: a comparison of three types of peritoneal access.
abstract: Peritoneal access for peritoneal dialysis (PD) poses a significant problem in infants due to their small size and can result in considerable morbidity and occasional mortality. This study was carried out to compare the complications associated with three different types of PH catheters for intermittent PD. A total of 79 session of PD were given to 51 infants with acute renal failure. Twenty-nine infants received 1, 18 received 2 and 2 infants received 3 and 4 sessions of PD, respectively. For PD access an intravenous cannula was used in 36, stylet catheter in 18, and guide wire inserted femoral vein catheter in 25 procedures. Percentage reduction of serum creatinine per PD session was comparable in infants being dialysed with different types of PD access. Local puncture site and intraperitoneal bleed were associated with the use of a stylet catheter during 4 procedures each (22.2%). Catheter blockade was commonest with the intravenous cannula (22.2%), followed by guide wire inserted femoral vein catheter (16%), and was least with the stylet catheter (5.5%). Total mechanical complications were lower with guide wire inserted femoral vein catheter (16%) as compared to intravenous cannula (25%) and stylet catheter (66%) (p < 0.05). There were 4 episodes of peritonitis (5.0%), 3 bacterial and 1 fungal. Although peritonitis was more common with intravenous cannula (8.3%) than guide wire inserted catheter (4%) and stylet catheter (nil), the difference was not statistically significant. Total complications including mechanical and infective were least with guide wire inserted femoral vein catheter (20%), followed by intravenous cannula (33%) and stylet catheter (66%) (p < 0.05). Of 51 infants, 20 died (39.0%). The PD procedure per se resulted in mortality in 2 cases, 1 because of massive intraperitoneal bleed due to stylet induced injury of an intra abdominal blood vessel and the other due to fungal peritonitis. To conclude, of the three types of access for intermittent PD, complications related to the PD procedure are the least with guide wire inserted femoral vein catheter.
authors.affiliation: Department of Nephrology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: H S
authors.initials: HS
authors.lastname: Kohli
authors.forename: A
authors.initials: A
authors.lastname: Barkataky
authors.forename: R S
authors.initials: RS
authors.lastname: Kumar
authors.forename: K
authors.initials: K
authors.lastname: Sud
authors.forename: V
authors.initials: V
authors.lastname: Jha
authors.forename: K L
authors.initials: KL
authors.lastname: Gupta
authors.forename: V
authors.initials: V
authors.lastname: Sakhuja
mesh_terms: D058186:Acute Kidney Injury / Q000097:blood / Q000150:complications / Q000628:therapy*; D002408:Catheters, Indwelling / Q000009:adverse effects; D003404:Creatinine / Q000097:blood; D005268:Femoral Vein; D006465:Hemoperitoneum / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D010530:Peritoneal Dialysis / Q000379:methods* / Q000401:mortality; D010538:Peritonitis / Q000453:epidemiology / Q000209:etiology; D012189:Retrospective Studies; D015996:Survival Rate
chemical_list: D003404:Creatinine