title: Scanning laser densitometry in visual acuity loss of unknown origin.
abstract: OBJECTIVE
  To assess foveal cone photoreceptor function in patients with unexplained loss of central visual acuity.
  
  
  METHODS
  Testing of foveal cone photoreceptor function was performed using scanning laser densitometry, colour matching (Rayleigh equation), and pattern electroretinography (ERG). Standard tests included full field ERG, electrooculography, visual evoked potentials, static perimetry, and fluorescein angiography.
  
  
  RESULTS
  Decreased foveal cone photopigment density and abnormal pattern ERG were found in three patients. Results of colour matching were not unequivocal.
  
  
  CONCLUSIONS
  Testing of foveal cone photoreceptor function using scanning laser densitometry may determine the location of pathological changes in certain patients with unexplained visual loss.
authors.affiliation: Helmholtz Institute, Department of Ophthalmology, Utrecht University, The Netherlands.
authors.forename: P J
authors.initials: PJ
authors.lastname: DeLint
authors.forename: J E
authors.initials: JE
authors.lastname: Keunen
authors.forename: A T
authors.initials: AT
authors.lastname: Liem
authors.forename: D
authors.initials: D
authors.lastname: van Norren
mesh_terms: D000293:Adolescent; D000328:Adult; D016022:Case-Control Studies; D003119:Color Perception Tests; D003720:Densitometry / Q000379:methods*; D004585:Electrooculography; D004596:Electroretinography; D005260:Female; D005584:Fovea Centralis; D006801:Humans; D007834:Lasers; D008297:Male; D008875:Middle Aged; D017949:Retinal Cone Photoreceptor Cells / Q000473:pathology; D012168:Retinal Pigments / Q000032:analysis*; D014786:Vision Disorders / Q000175:diagnosis*; D014787:Vision Tests; D014792:Visual Acuity
chemical_list: D012168:Retinal Pigments