title: Rho GTPases and leukocyte cytoskeletal regulation.
abstract: The Rho GTPases (Rho, Rac, and Cdc42) regulate assembly of the actin cytoskeleton in many cells, including leukocytes. Recent work in identifying the protein targets of these GTPases is providing greater insight into the mechanisms used by cells to control cytoskeletal dynamics for a variety of purposes.
authors.affiliation: Department of Immunology, Scripps Research Institute, La Jolla, CA 92037, USA.
authors.forename: S
authors.initials: S
authors.lastname: Dharmawardhane
authors.forename: G M
authors.initials: GM
authors.lastname: Bokoch
mesh_terms: D000818:Animals; D003599:Cytoskeleton / Q000502:physiology*; D020558:GTP Phosphohydrolases / Q000502:physiology*; D019204:GTP-Binding Proteins / Q000502:physiology*; D006801:Humans; D007962:Leukocytes / Q000502:physiology* / Q000648:ultrastructure; D008565:Membrane Proteins / Q000502:physiology*; D020743:rhoB GTP-Binding Protein
chemical_list: D008565:Membrane Proteins; D020558:GTP Phosphohydrolases; D019204:GTP-Binding Proteins; D020743:rhoB GTP-Binding Protein