Investigation of the electrostatic field of the papain active centre by using monoprotonated and diprotonated pyridyl (Py) disulphides as reactivity probes.
Gul
S
S
Department of Biochemistry, Queen Mary and Westfield College, University of London, UK.
Clarke
A
A
Field
B
B
Thomas
M P
MP
Willenbrock
F
F
Pinitglang
S
S
Verma
C
C
Thomas
E W
EW
Brocklehurst
K
K
D001665:Binding Sites; D004220:Disulfides / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D010206:Papain / Q000737:chemistry* / Q000378:metabolism*; D011725:Pyridines / Q000494:pharmacology*; D055672:Static Electricity; D013329:Structure-Activity Relationship
D004220:Disulfides; D011725:Pyridines; D010206:Papain