title: Mid-term results of mitral valve replacement combined with chordae tendineae replacement in patients with mitral stenosis.
abstract: OBJECTIVE
  Although many studies have found that preservation of the continuity between the mitral annulus and the papillary muscles during mitral valve replacement improves postoperative left ventricular performance in patients with mitral regurgitation, much less research has been done in this respect in patients with mitral stenosis. We reviewed our experience with mitral valve replacement combined with chordae tendineae replacement in 29 patients with mitral disease, 26 of whom had mitral stenosis.
  
  
  METHODS
  During mitral valve replacement, continuity between the papillary muscle and annulus was restored with expanded polytetrafluoroethylene (ePTFE) mattress sutures, which were threaded into the compact portion of each papillary muscle and placed at the 2, 4, 8 and 10 o'clock positions in the mitral annulus. Postoperatively, the patients were followed by echocardiographic assessment and exercise (stress) radionuclide angiography testing. The stress test results were compared with those in patients who had undergone traditional mitral valve replacement, and also those in normal people.
  
  
  RESULTS
  There were no hospital deaths, complications, or cardiac deaths or events during a median follow up of two-and-a-half years. Echocardiography showed no postoperative cardiac dilatation. The stress tests found no significant differences between the ejection fraction in mitral stenosis patients who underwent conventional mitral valve replacement and in those who had valve replacement combined with ePTFE chordae tendineae replacement.
  
  
  CONCLUSIONS
  A direct advantage of chordae-preserving mitral valve replacement over conventional replacement with respect to postoperative global left ventricular performance in patients with mitral valve stenosis has not been demonstrated. However, postoperative regional left ventricular contraction in patients with mitral stenosis has been observed to be better among those who have undergone the chordae-preserving procedure. Additional investigations are needed to elucidate the effects of this procedure in mitral stenosis, but we believe that the technique improves left ventricular performance and may decrease the risk of left ventricular rupture.
authors.affiliation: Department of Cardiovascular Surgery, Tenri Hospital, Nara, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Okita
authors.forename: S
authors.initials: S
authors.lastname: Miki
authors.forename: Y
authors.initials: Y
authors.lastname: Ueda
authors.forename: T
authors.initials: T
authors.lastname: Tahata
authors.forename: H
authors.initials: H
authors.lastname: Ogino
authors.forename: T
authors.initials: T
authors.lastname: Sakai
authors.forename: K
authors.initials: K
authors.lastname: Morioka
authors.forename: K
authors.initials: K
authors.lastname: Matsubayashi
authors.forename: T
authors.initials: T
authors.lastname: Nomoto
mesh_terms: D000328:Adult; D000368:Aged; D002815:Chordae Tendineae / Q000601:surgery*; D004452:Echocardiography; D006350:Heart Valve Prosthesis / Q000401:mortality; D006801:Humans; D008722:Methods; D008875:Middle Aged; D008943:Mitral Valve; D008946:Mitral Valve Stenosis / Q000601:surgery*; D010210:Papillary Muscles / Q000601:surgery; D011138:Polytetrafluoroethylene; D011875:Radionuclide Angiography; D015996:Survival Rate; D013537:Sutures
chemical_list: D011138:Polytetrafluoroethylene