title: The incidence and distribution of ochratoxin A in western Canadian swine.
abstract: A survey of swine destined for slaughter in Manitoba was conducted to examine the incidence of ochratoxin A (OA) in swine herds from different regions of Manitoba throughout the year 1989-90. Thirty-six percent of the serum samples which were collected from 1600 pigs contained detectable levels of OA. The identity of this toxin was confirmed using liquid chromatography-mass spectrometry and enzymatic hydrolysis. There was a significant effect of the region from which the herds originated, as well as the season in which the samples were collected on both the incidence (p < 0.001) and concentration of OA (p < 0.001). In July, 65% of the samples contained detectable levels of OA, compared with 38, 21 and 17%, in April, October and January respectively. Furthermore, 24% of the samples collected in July contained greater than 15 ng/ml of OA, while only 2, 9, and 1% of the samples collected in April, October and January respectively, contained greater than 15 ng/ml of OA. Based on the six samples collected from each herd, it appears that the presence and concentration of OA within a herd may be estimated from a limited number of animals per herd.
authors.affiliation: Department of Animal Science, Faculty of Agricultural and Food Sciences, University of Manitoba, Winnipeg, Canada.
authors.forename: K H
authors.initials: KH
authors.lastname: Ominski
authors.forename: A A
authors.initials: AA
authors.lastname: Frohlich
authors.forename: R R
authors.initials: RR
authors.lastname: Marquardt
authors.forename: G H
authors.initials: GH
authors.lastname: Crow
authors.forename: D
authors.initials: D
authors.lastname: Abramson
mesh_terms: D000818:Animals; D002273:Carcinogens / Q000032:analysis* / Q000378:metabolism; D016009:Chi-Square Distribution; D002851:Chromatography, High Pressure Liquid; D002853:Chromatography, Liquid; D006868:Hydrolysis; D015994:Incidence; D008137:Longitudinal Studies; D008350:Manitoba; D013058:Mass Spectrometry; D009183:Mycotoxins / Q000097:blood*; D009793:Ochratoxins / Q000097:blood*; D012015:Reference Standards; D012621:Seasons; D013552:Swine / Q000097:blood*; D014018:Tissue Distribution
chemical_list: D002273:Carcinogens; D009183:Mycotoxins; D009793:Ochratoxins; C025589:ochratoxin A