Time-resolved white light transillumination for optical imaging.
OBJECTIVE
To describe a new breast-imaging method with the potential of multi-spectral optical transillumination based on a time-resolved technique.


METHODS
A breast phantom was irradiated with ultra-short laser pulses of white light generated by self-phase modulation of an incident high-power laser pulse in water. Time-resolved detection of the transmitted light was performed. Contrast resolution was studied using different absorbers located inside the breast phantom.


CONCLUSIONS
The results showed that simultaneous, multi-spectral transillumination is possible. The technique can also be used for measurements of optical properties in tissue.
Jarlman
O
O
Department of Diagnostic Radiology, University Hospital, Lund, Sweden.
Berg
R
R
Andersson-Engels
S
S
Svanberg
S
S
Pettersson
H
H
D001940:Breast; D004867:Equipment Design; D005260:Female; D006801:Humans; D007834:Lasers; D019047:Phantoms, Imaging; D012117:Resins, Synthetic; D013997:Time Factors; D014172:Transillumination / Q000295:instrumentation / Q000379:methods*
D012117:Resins, Synthetic; C010102:delrin