Endothelin-1 acts through ETA receptors to stimulate aldosterone secretion by the rat adrenal gland.
Hinson
J P
JP
Department of Biochemistry, Queen Mary and Westfield College, London.
Cameron
L A
LA
Puddefoot
J R
JR
Kapas
S
S
D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000450:Aldosterone / Q000378:metabolism*; D000804:Angiotensin II / Q000494:pharmacology; D000818:Animals; D001665:Binding Sites; D065128:Endothelin Receptor Antagonists; D019332:Endothelin-1 / Q000378:metabolism / Q000494:pharmacology*; D066298:In Vitro Techniques; D007700:Kinetics; D010456:Peptides, Cyclic / Q000494:pharmacology; D011869:Radioligand Assay; D051381:Rats; D044022:Receptor, Endothelin A; D017466:Receptors, Endothelin / Q000502:physiology*; D015384:Zona Glomerulosa / Q000187:drug effects / Q000502:physiology*
D065128:Endothelin Receptor Antagonists; D019332:Endothelin-1; D010456:Peptides, Cyclic; D044022:Receptor, Endothelin A; D017466:Receptors, Endothelin; D000804:Angiotensin II; D000450:Aldosterone; D000324:Adrenocorticotropic Hormone; C072247:cyclo(Trp-Asp-Pro-Val-Leu)