Mutation of the conserved amino acids of mitochondria aldehyde dehydrogenase. Role of the conserved residues in the mechanism of reaction.
Sheikh
S
S
Department of Biochemistry, Purdue University, West Lafayette, Indiana 47907-1153, USA.
Ni
L
L
Weiner
H
H
D000444:Aldehyde Dehydrogenase / Q000737:chemistry / Q000378:metabolism*; D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D003001:Cloning, Molecular; D017124:Conserved Sequence; D004926:Escherichia coli; D006801:Humans; D007700:Kinetics; D008930:Mitochondria, Liver / Q000201:enzymology*; D016297:Mutagenesis, Site-Directed; D009243:NAD / Q000378:metabolism; D017354:Point Mutation; D051381:Rats; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism
D011994:Recombinant Proteins; D009243:NAD; D000444:Aldehyde Dehydrogenase