title: Hypertension in pregnancy: current concepts of preeclampsia.
abstract: Hypertensive disorders (gestational hypertension, preeclampsia, chronic hypertension, superimposed preeclampsia) are the most common medical complications of pregnancy and constitute a major cause of maternal and perinatal morbidity and mortality. Prediction of those women destined to develop preeclampsia remains elusive. The benefits of calcium supplementation for prevention of preeclampsia are encouraging; however, the definitive study is not yet complete. Aspirin therapy for high-risk has not been helpful; results of therapy for high-risk women are pending. More experience is being gained with antihypertensive therapy and expectant management in severe preeclampsia. Conservative management of severe preeclampsia, when performed in a tertiary care center, may benefit a select group of women and their fetuses.
authors.affiliation: Department of Obstetrics and Gynecology, University of Tennessee, Memphis 38103, USA.
authors.forename: A G
authors.initials: AG
authors.lastname: Witlin
authors.forename: B M
authors.initials: BM
authors.lastname: Sibai
mesh_terms: D000959:Antihypertensive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004461:Eclampsia / Q000188:drug therapy / Q000209:etiology / Q000401:mortality; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011225:Pre-Eclampsia / Q000188:drug therapy* / Q000209:etiology / Q000401:mortality; D011247:Pregnancy; D011256:Pregnancy Outcome; D018566:Pregnancy, High-Risk; D015996:Survival Rate; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents