title: Fluoride level in saliva after bonding orthodontic brackets with a fluoride containing adhesive.
abstract: The fluoride level in saliva is considered an important parameter in caries prevention. Elevation of the salivary fluoride level by a fluoride-releasing orthodontic bonding adhesive would most likely be beneficial in the prevention of enamel caries. In this study, the fluoride level in saliva was measured after bonding brackets with a visible light-curing adhesive containing fluoride (12.4 wt% total F). The fluoride released from the adhesive has been shown in a previous study to inhibit demineralization adjacent to orthodontic brackets in vivo. Twenty-four patients each had 20 brackets bonded and saliva samples taken before bonding (t = 0) and after 1, 3, and 6 months. The participants were requested to brush daily with a fluoride toothpaste during the study period. The saliva fluoride analysis was done with the microdiffusion method. The analysis of the saliva showed fluoride levels (+/- SD) of 0.011 +/- 0.007, 0.011 +/- 0.009, 0.0011 +/- 0.007, and 0.012 +/- 0.008 ppm at t = 0, 1, 3, and 6 months, respectively. There was no significant difference at the 5% level. The study indicated indirectly that the caries inhibiting effect of the orthodontic adhesive shown previously was most likely due to a localized fluoridation of the cariogenic environment rather than to an elevation of the fluoride level in saliva.
authors.affiliation: Department of Orthodontics, Faculty of Dentistry, University of Oslo, Norway.
authors.forename: B
authors.initials: B
authors.lastname: Ogaard
authors.forename: J
authors.initials: J
authors.lastname: Arends
authors.forename: H
authors.initials: H
authors.lastname: Helseth
authors.forename: G
authors.initials: G
authors.lastname: Dijkman
authors.forename: M
authors.initials: M
authors.lastname: van der Kuijl
mesh_terms: D000269:Adhesives / Q000737:chemistry*; D000293:Adolescent; D002327:Cariostatic Agents / Q000032:analysis*; D003692:Delayed-Action Preparations; D001840:Dental Bonding; D003731:Dental Caries / Q000517:prevention & control; D003743:Dental Enamel / Q000187:drug effects; D004058:Diffusion; D004566:Electrodes; D005459:Fluorides / Q000008:administration & dosage / Q000032:analysis* / Q000737:chemistry / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D016910:Orthodontic Brackets; D012463:Saliva / Q000737:chemistry*; D017001:Tooth Demineralization / Q000517:prevention & control; D014100:Toothpastes / Q000627:therapeutic use
chemical_list: D000269:Adhesives; D002327:Cariostatic Agents; D003692:Delayed-Action Preparations; D014100:Toothpastes; D005459:Fluorides