[A biological compatibility study of hydroxyapatite].
The biological compatibility of coatings of subcutaneous implants was studied in rat experiments. The implants were coated with hydroxyapatite and hydroxyapatite modified by chloromethylsilanthrane (silamine). The coatings were found to inhibit lipid peroxidation and form the optimal ratio of connective tissue biopolymers in capsules forming round the implants. Both types of hydroxyapatites used were characterized by high biological compatibility.
Trofimov
V V
VV
Klimenov
V A
VA
Kazimirovskaia
V B
VB
Mansurova
L A
LA
D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology* / Q000633:toxicity; D001704:Biopolymers; D003094:Collagen / Q000494:pharmacology / Q000633:toxicity; D015921:Dental Implants; D003764:Dental Materials / Q000494:pharmacology* / Q000633:toxicity; D004338:Drug Combinations; D017886:Durapatite / Q000494:pharmacology* / Q000633:toxicity; D007928:Lethal Dose 50; D015227:Lipid Peroxidation / Q000187:drug effects; D008422:Materials Testing / Q000379:methods / Q000706:statistics & numerical data; D051379:Mice; D017646:Organosilicon Compounds / Q000494:pharmacology / Q000633:toxicity; D011817:Rabbits; D051381:Rats; D014025:Titanium
D001672:Biocompatible Materials; D001704:Biopolymers; D015921:Dental Implants; D003764:Dental Materials; D004338:Drug Combinations; D017646:Organosilicon Compounds; C104011:Silimin; C033818:1-(chloromethyl)silatrane; D003094:Collagen; D017886:Durapatite; D014025:Titanium
Issledovanie biologicheskoĭ sovmestimosti gidroksiapatita.