Efficacy of doramectin against intestinal nematodes and sarcoptic manage mites in naturally infected swine.
Endectocidal efficacy of doramectin administered intramuscularly at a dosage of 300 micrograms/kg was evaluated in 464 pigs naturally infected with intestinal nematodes or mange mites on 14 commercial farms in Japan. By doramectin treatment, fecal egg counts were reduced > 99% for Ascaris suum, Strongyloides ransomi, Oesophagostomum dentatum, and Trichuris suis; worm counts of T. suis and mite counts of Sarcoptes scabiei reduced 90.1% on Day 21 and 99.5% on Day 28 following treatment, respectively.
Saeki
H
H
Department of Parasitology, Nippon Veterinary and Animal Science University, Tokyo, Japan.
Fujii
T
T
Fukumoto
S
S
Kagota
K
K
Taneichi
A
A
Takeda
S
S
Tsukaguchi
M
M
D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage / Q000627:therapeutic use*; D001196:Ascariasis / Q000188:drug therapy / Q000662:veterinary; D017165:Ascaris suum / Q000302:isolation & purification; D005243:Feces / Q000469:parasitology; D005260:Female; D007275:Injections, Intravenous / Q000662:veterinary; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy / Q000662:veterinary*; D007559:Ivermectin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary*; D009814:Oesophagostomiasis / Q000188:drug therapy / Q000662:veterinary; D009815:Oesophagostomum / Q000302:isolation & purification; D010270:Parasite Egg Count / Q000662:veterinary; D012532:Scabies / Q000188:drug therapy / Q000662:veterinary*; D012867:Skin / Q000469:parasitology; D013321:Strongyloides / Q000302:isolation & purification; D013322:Strongyloidiasis / Q000188:drug therapy / Q000662:veterinary; D013552:Swine; D013553:Swine Diseases / Q000188:drug therapy*; D013997:Time Factors; D014257:Trichuriasis / Q000188:drug therapy / Q000662:veterinary; D014258:Trichuris / Q000302:isolation & purification
D000871:Anthelmintics; D007559:Ivermectin; C084101:doramectin