Comparison of two plate-haptic intraocular lenses in a rabbit model.
OBJECTIVE
To compare the presence of fibrosis through footplate positioning holes in two different silicone intraocular lenses (IOLs) following phacoemulsification with IOL implantation.


METHODS
Moran Eye Center, University of Utah, Salt Lake City.


METHODS
Twelve New Zealand white rabbits had phacoemulsification with placement of a control silicone IOL in one eye and a study IOL with a larger positioning hole in the opposite eye. The amount of force required to remove the IOLs from the capsular bag was analyzed at 3 and 6 weeks postoperatively.


RESULTS
The force necessary to remove the study lens with the larger positioning holes was statistically significantly greater at both 3 and 6 weeks than that necessary to remove the control lenses. Capsular fibrosis with proliferative lens cortical material through the larger positioning holes was also documented grossly using the Miyake technique.


CONCLUSIONS
The larger footplate positioning holes in the study silicone IOL significantly increased capsular bag fixation in the rabbit model following phacoemulsification and IOL implantation.
Mamalis
N
N
Department of Ophthalmology, University of Utah, Salt Lake City 84132, USA.
Omar
O
O
Veiga
J
J
Tanner
D
D
Pirayesh
A
A
Fernquist
D S
DS
D000818:Animals; D002455:Cell Division; D004195:Disease Models, Animal; D005355:Fibrosis / Q000209:etiology / Q000473:pathology; D005500:Follow-Up Studies; D007903:Lens Capsule, Crystalline / Q000473:pathology / Q000601:surgery; D007910:Lenses, Intraocular / Q000009:adverse effects; D018918:Phacoemulsification / Q000379:methods; D011183:Postoperative Complications / Q000209:etiology / Q000473:pathology*; D011474:Prosthesis Design; D011817:Rabbits; D012826:Silicone Elastomers / Q000009:adverse effects
D012826:Silicone Elastomers