title: Cervical gangliectomy does not affect in vitro tryptophan hydroxylase activity in rat brain base arteries.
abstract: The presence of a serotonergic innervation in rat cerebral arteries of peripheral origin was explored. Superior cervical ganglia removal did not change tryptophan hydroxylase activity measured in cell-free extracts of brain base vessels. A low enzyme activity was detected in the ganglia. These results suggest that rat cerebral arteries do not receive a serotonergic innervation from the superior cervical ganglia.
authors.affiliation: Departamento de Fisiología, Facultad de Medicina, Universidad Autonóma de Madrid, Spain.
authors.forename: M J
authors.initials: MJ
authors.lastname: Moreno
authors.forename: A L
authors.initials: AL
authors.lastname: López de Pablo
authors.forename: E J
authors.initials: EJ
authors.lastname: Marco
mesh_terms: D000818:Animals; D002536:Cerebral Arteries / Q000201:enzymology* / Q000294:innervation; D015171:Ganglionectomy; D008297:Male; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D012701:Serotonin / Q000378:metabolism / Q000502:physiology; D017783:Superior Cervical Ganglion / Q000201:enzymology / Q000502:physiology; D013562:Sympathectomy; D014365:Tryptophan Hydroxylase / Q000378:metabolism*
chemical_list: D012701:Serotonin; D014365:Tryptophan Hydroxylase; D009638:Norepinephrine