[The correction of the thyroid status in the surgical treatment of malignant tumors of the stomach and large intestine].
We evaluated changes in thyroid status of patients with carcinoma of the stomach and large intestine in pre- and postoperative periods under the influence of triiodothyronine (T3) prescribed to make up for deficient endogenous hormone. With T3 returning to normal in preoperative period, T4 blood level gets lowered from the upper limit of the norm to the lower one. However these patients show unchanged blood T4 concentration after surgical intervention, while without administration of T3 the level of T4 decreases. Prescription of T3 promotes greater depression of thyroid-stimulating hormone in pre- and postoperative periods. Incorporation of T3 into conventional corrective therapy of metabolism tends to improve the immediate results of surgical treatment of malignant tumours of the stomach and large intestine.
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D000230:Adenocarcinoma / Q000097:blood / Q000601:surgery*; D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000097:blood / Q000601:surgery*; D007420:Intestine, Large; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000097:blood / Q000601:surgery*; D013961:Thyroid Gland / Q000503:physiopathology*; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000008:administration & dosage / Q000097:blood / Q000172:deficiency
D014284:Triiodothyronine; D013974:Thyroxine
Korrektsiia tireoidnogo statusa pri khirurgicheskom lechenii zlokachestvennykh opukholeĭ zheludka i tolstoĭ kishki.