Helicobacter pylori and its interaction with chief and parietal cells.
Helicobacter pylori has been shown, along with other Helicobacter species to produce effector molecules that induce substantial physiological changes on acid and pepsin secretion. The effects are clinically evident, and long-term achlorhydria may be a risk factor for gastric cancer. Further identification and characterization of the factors may lead to additional understanding of gastric physiology.
Cave
D R
DR
St. Elizabeth's Medical Center, Boston, Massachusetts 02135, USA.
D000126:Achlorhydria / Q000209:etiology / Q000382:microbiology; D000818:Animals; D016481:Helicobacter Infections / Q000209:etiology; D016480:Helicobacter pylori / Q000472:pathogenicity*; D006801:Humans; D010295:Parietal Cells, Gastric / Q000382:microbiology*