[Double cardiac fibroma in a newborn infant].
The authors describe the autopsy finding of two fibromas within the left ventricular wall of a five-day-old newborn. Histochemistry and immunohistochemistry showed the lesion as a purely fibroblastic proliferation, with intense elastic fibers formation and secondary morphological alteration and biological damage of the pre-existing muscular fibers. The authors, on the basis of the phases of the cardiac metamers development and of myocardial tissue differentiation, exclude any relationship with disembryogenetic factors, and hence the hamartomatous origin of the lesion, despite their onset in the first months of intrauterine growth.
Aliperta
A
A
Servizio di Anatomia ed Istologia Patologica, Presidio Ospedaliero V. Monaldi, Napoli.
De Rosa
N
N
Aliperta
M
M
Palumbo
A
A
D017809:Fatal Outcome; D005350:Fibroma / Q000151:congenital / Q000473:pathology*; D006338:Heart Neoplasms / Q000151:congenital / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000151:congenital / Q000473:pathology*
Fibroma cardiaco doppio in neonato.