Rhabdoid phenotype in squamous carcinoma. A report of two cases.
We report two cases of squamous carcinoma in which a prominent rhabdoid phenotype was seen. The tumors which occurred in the buccal mucosa of a 70 year old man and the skin of a 85 year old man were positive for cytokeratin and epithelial membrane antigen indicating their epithelial nature. Co-expression of vimentin was also noted. The aggressive nature of the rhabdoid component is confirmed by the fact that the cervical lymph node metastasis in case I was also rhabdoid.
Pai
S A
SA
Department of Pathology, Tata Memorial Hospital, Parel, Mumbai, India.
Vege
D S
DS
Borges
A M
AM
Soman
C S
CS
D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000556:secondary; D017809:Fatal Outcome; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D009062:Mouth Neoplasms / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010641:Phenotype; D018335:Rhabdoid Tumor / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*