title: 44-Homooligomycin E, a new cytotoxic macrolide antibiotic from Streptomyces ostreogriseus.
abstract: Homooligomycin E (1) was isolated from the culture broth of Streptomyces ostreogriseus and its structure was analyzed on the basis of physicochemical and spectroscopic data. It showed strong cytotoxicity against several human tumor cell lines.
authors.affiliation: KRIBB, Korea Institute of Science and Technology, Yusung, Taejon, Korea.
authors.forename: H S
authors.initials: HS
authors.lastname: Kim
authors.forename: H J
authors.initials: HJ
authors.lastname: Band
authors.forename: S Y
authors.initials: SY
authors.lastname: Lee
authors.forename: O J
authors.initials: OJ
authors.lastname: Yoo
authors.forename: J C
authors.initials: JC
authors.lastname: Yoo
authors.forename: Y H
authors.initials: YH
authors.lastname: Kim
authors.forename: J J
authors.initials: JJ
authors.lastname: Lee
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D000903:Antibiotics, Antineoplastic / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D009840:Oligomycins / Q000737:chemistry*; D013302:Streptomyces / Q000737:chemistry*; D014407:Tumor Cells, Cultured
chemical_list: C105048:44-homooligomycin E; D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; D009840:Oligomycins