title: LHRH induced changes in the interrenal gland of the frog Rana cyanophlyctis (Schn.).
abstract: Administration (i.m.) of synthetic mammalian LHRH (40 ng/frog, alternate day for 30 days) to adult male intact frogs R. cyanophlyctis resulted in activation of the interrenal cells as shown by increases in nuclear diameters of the interrenal cells, activity (histochemical demonstration) of delta 5-3 beta-hydroxysteroid dehydrogenase and glucose-6-phosphate dehydrogenase and concomitant decrease in sudanophilic lipid droplets in the interrenal gland when compared to those of controls. These changes were not observed in the interrenal gland of LHRH treated hypophysectomized frogs. The results indicate that LHRH stimulates secretory activity of the interrenal cells and action may not be directly on the adrenal gland.
authors.affiliation: Department of Zoology, Karnataka University, Dharwad, India.
authors.forename: H N
authors.initials: HN
authors.lastname: Yajurvedi
authors.forename: M A
authors.initials: MA
authors.lastname: Hooli
mesh_terms: D015096:3-Hydroxysteroid Dehydrogenases / Q000378:metabolism; D000818:Animals; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology*; D007016:Hypophysectomy; D007401:Interrenal Gland / Q000166:cytology / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D010902:Pituitary Gland / Q000502:physiology; D011898:Ranidae
chemical_list: D007987:Gonadotropin-Releasing Hormone; D015096:3-Hydroxysteroid Dehydrogenases; C031954:delta(5)-3 beta-hydroxysteroid dehydrogenase; D005954:Glucosephosphate Dehydrogenase