title: Candida splenic abscess in the absence of obvious immunodeficiency.
abstract: Focal hepatosplenic candidiasis has been increasingly recognized as a variant of disseminated candidiasis in immunocompromised patients. It rarely presents as Candida splenic abscess. Its occurrence in non-leukemic patients is quite rare. A patient with diabetes mellitus and previously undiagnosed sickle cell trait presented with upper gastrointestinal bleeding. Candida splenic abscess was diagnosed. She was successfully treated with percutaneous drainage and fluconazole. The clinical presentation, diagnosis, and treatment of Candida splenic abscess is reviewed, and its relationship to diabetes mellitus and sickle cell disease without major immunodeficiency is discussed.
authors.affiliation: Division of Digestive Diseases and Nutrition, University of South Carolina School of Medicine, Columbia, USA.
authors.forename: A
authors.initials: A
authors.lastname: Kapur
authors.forename: R
authors.initials: R
authors.lastname: Vasudeva
authors.forename: C W
authors.initials: CW
authors.lastname: Howden
mesh_terms: D000038:Abscess / Q000175:diagnosis* / Q000628:therapy; D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000175:diagnosis* / Q000628:therapy; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D004322:Drainage; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D008875:Middle Aged; D012805:Sickle Cell Trait / Q000150:complications; D013158:Splenic Diseases / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole