title: Consultation system for diagnosis of gastric lesions.
abstract: OBJECTIVE
  To present a knowledge-based classification system, GASTRO, for gastric lesion diagnosis.
  
  
  METHODS
  The study group consisted of 150 patients with various gastric lesions (25 relatively normal, 30 gastritic changed, 25 ulcerous, 25 adenomatous, 25 cancerous and 20 metastatic cases). After a subtotal gastrectomy, the lesions were routinely diagnosed and quantitatively evaluated. The control group consisted of 25 patients with relatively normal mucosae. Both quantitative methods were used for determining the dynamics of malignant processes of gastric mucosa.
  
  
  RESULTS
  During the consultation more than 20 factors influencing disease dynamics were considered. Statistics on cellular and nuclear parameter changes in stomach mucosa were also used in the diagnosis of gastric lesions.
  
  
  CONCLUSIONS
  Diagnoses were generated with confidence levels of 90%, 95%, and 99%. The final decision remained the responsibility of the physician.
authors.affiliation: Department of Pathology, Third City Hospital, Sofia, Bulgaria.
authors.forename: V
authors.initials: V
authors.lastname: Enchev
authors.forename: J
authors.initials: J
authors.lastname: Angelova
authors.forename: J
authors.initials: J
authors.lastname: Peneva
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology; D002277:Carcinoma / Q000175:diagnosis / Q000473:pathology; D002467:Cell Nucleus; D048429:Cell Size; D019411:Clinical Laboratory Techniques / Q000706:statistics & numerical data*; D004247:DNA / Q000032:analysis; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D012017:Referral and Consultation; D013272:Stomach Diseases / Q000175:diagnosis* / Q000473:pathology; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000473:pathology
chemical_list: D004247:DNA