title: Leiomyosarcoma of the pulmonary vein: case report with immunohistochemical and ultrastructural findings.
abstract: We report a case of neoplasia of pulmonary vein in a 45-year-old woman who presented with increasing dyspnea. As a consequence, the neoplasia filled the entire left atrium and appeared to be attached to the left superior pulmonary vein on surgical excision. Histologically, it was composed of a proliferation of sarcomatous cells, with a high mitotic rate and diffuse immunohistochemical positivity for smooth muscle actin, consistent with a leiomyosarcoma. The microscopic, immunohistochemical, and ultrastructural findings are discussed.
authors.affiliation: Institute of Pathology, University of Bologna, Italy.
authors.forename: O
authors.initials: O
authors.lastname: Leone
authors.forename: S
authors.initials: S
authors.lastname: Piana
authors.forename: G
authors.initials: G
authors.lastname: Cenacchi
authors.forename: P A
authors.initials: PA
authors.lastname: Farneti
authors.forename: E
authors.initials: E
authors.lastname: Pilato
authors.forename: D
authors.initials: D
authors.lastname: Pacini
authors.forename: R
authors.initials: R
authors.lastname: Galli
authors.forename: D
authors.initials: D
authors.lastname: Santini
authors.forename: S
authors.initials: S
authors.lastname: Pileri
mesh_terms: D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007890:Leiomyosarcoma / Q000737:chemistry* / Q000473:pathology / Q000648:ultrastructure*; D008875:Middle Aged; D011667:Pulmonary Veins / Q000737:chemistry* / Q000473:pathology / Q000648:ultrastructure*; D019043:Vascular Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure*