Gingival hyperplasia: interaction between cyclosporin A and nifedipine? A case report.
Treatment with either cyclosporin A or nifedipine may induce gingival hyperplasia. A case report is presented which describes a patient medicated simultaneously with both drugs and who subsequently developed extreme hyperplasia. Could such a severe gingival pathology have resulted from an additive interaction between the two drugs?
Jackson
C
C
Department of Dentistry, Long Island College Hospital, Brooklyn, USA.
Babich
S
S
D002121:Calcium Channel Blockers / Q000009:adverse effects*; D016572:Cyclosporine / Q000009:adverse effects*; D004357:Drug Synergism; D005260:Female; D005885:Gingival Hyperplasia / Q000139:chemically induced* / Q000601:surgery; D005888:Gingival Pocket / Q000139:chemically induced / Q000601:surgery; D005890:Gingivectomy; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008875:Middle Aged; D009543:Nifedipine / Q000009:adverse effects*
D002121:Calcium Channel Blockers; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D009543:Nifedipine