Effect of aging on the amide group of bone matrix, measured by FTIR spectrophotometry, in adult subjects deceased as a result of violent death.
In order to determine the effects of age on bone quality, human bone tissue taken from adult subjects deceased from violent death was analyzed by means of fast Fourier transform infrared spectrophotometry (FTIR) in the Diffuse Reflectance mode (DR). This technique allows the characterization of both the mineral and organic parts of bone in a nondestructive manner. Only the organic part is discussed in this report. A quantitative change in the entire organic part of bone tissue is observed with the aging of subjects. The effects of these changes on bone strength were not measured.
Very
J M
JM
LBTO/GIP Exercise, Faculté de Medicine, Saint-Elienne, France.
Gibert
R
R
Guilhot
B
B
Debout
M
M
Alexandre
C
C
D000293:Adolescent; D000328:Adult; D000368:Aged; D000375:Aging / Q000473:pathology*; D000577:Amides / Q000032:analysis*; D001857:Bone Matrix / Q000737:chemistry* / Q000648:ultrastructure; D001842:Bone and Bones / Q000737:chemistry*; D003645:Death, Sudden; D006801:Humans; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D012016:Reference Values; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods*
D000577:Amides