title: Low-dose aspirin and intracranial surgery. A survey of the opinions of consultant neuroanaesthetists in the UK.
abstract: Increasing numbers of patients presenting for surgery are receiving concurrent medication with low-dose aspirin. We surveyed the opinions and working practices of consultant members of the Neuroanaesthesia Society regarding patients who present for elective intracranial surgery whilst taking this form of medication. Identical questionnaires were sent to 140 members of the society and proffered four main questions: (1) the adherence to any policy of stopping aspirin preoperatively, (2) the preferred method of treatment for excessive bleeding in this context, (3) personal knowledge of haemorrhagic complications in this group of patients, (4) the neurosurgical unit concerned. There were 121 responses (86.4%) of which 116 (82.9%) were valid. Of the respondents, 78 (67.2%) were unaware of a written departmental policy for the discontinuation of pre-operative aspirin treatment and had no personal policy. Thirty-two respondents (27.6%) had a personal policy but were unaware of a written departmental policy; only six respondents (5.2%) stated that a written departmental policy was in place. The mean time suggested for discontinuation of aspirin pre-operatively was 11.3 days (range: 1-42 days). Fifty-one respondents (44.0%) considered that patients taking low-dose aspirin were at increased risk of excessive perioperative haemorrhage and 15 (12.9%) anaesthetists reported having personal experience of such problems. Fifty-seven respondents (49.1%) would use a platelet infusion, alone or in association with other blood products or prohaemostatic agents, if haemorrhagic complications developed. The majority of neuroanaesthetists felt that aspirin was a risk factor for haemorrhagic complications associated with intracranial procedures, but most adopt no policy regarding its preoperative discontinuation.
authors.affiliation: Department of Anaesthesia, National Hospital for Neurology and Neurosurgery, London, UK.
authors.forename: D N
authors.initials: DN
authors.lastname: James
authors.forename: J R
authors.initials: JR
authors.lastname: Fernandes
authors.forename: I
authors.initials: I
authors.lastname: Calder
authors.forename: M
authors.initials: M
authors.lastname: Smith
mesh_terms: D000776:Anesthesiology; D001241:Aspirin / Q000009:adverse effects*; D001291:Attitude of Health Personnel; D001921:Brain / Q000601:surgery*; D003253:Consultants / Q000523:psychology; D004334:Drug Administration Schedule; D006801:Humans; D008505:Medical Staff, Hospital / Q000523:psychology; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects*; D019106:Postoperative Hemorrhage / Q000139:chemically induced / Q000628:therapy; D011364:Professional Practice; D006113:United Kingdom
chemical_list: D010975:Platelet Aggregation Inhibitors; D001241:Aspirin