title: Efficacy of doramectin against intestinal nematodes and sarcoptic manage mites in naturally infected swine.
abstract: Endectocidal efficacy of doramectin administered intramuscularly at a dosage of 300 micrograms/kg was evaluated in 464 pigs naturally infected with intestinal nematodes or mange mites on 14 commercial farms in Japan. By doramectin treatment, fecal egg counts were reduced > 99% for Ascaris suum, Strongyloides ransomi, Oesophagostomum dentatum, and Trichuris suis; worm counts of T. suis and mite counts of Sarcoptes scabiei reduced 90.1% on Day 21 and 99.5% on Day 28 following treatment, respectively.
authors.affiliation: Department of Parasitology, Nippon Veterinary and Animal Science University, Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Saeki
authors.forename: T
authors.initials: T
authors.lastname: Fujii
authors.forename: S
authors.initials: S
authors.lastname: Fukumoto
authors.forename: K
authors.initials: K
authors.lastname: Kagota
authors.forename: A
authors.initials: A
authors.lastname: Taneichi
authors.forename: S
authors.initials: S
authors.lastname: Takeda
authors.forename: M
authors.initials: M
authors.lastname: Tsukaguchi
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000008:administration & dosage / Q000627:therapeutic use*; D001196:Ascariasis / Q000188:drug therapy / Q000662:veterinary; D017165:Ascaris suum / Q000302:isolation & purification; D005243:Feces / Q000469:parasitology; D005260:Female; D007275:Injections, Intravenous / Q000662:veterinary; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy / Q000662:veterinary*; D007559:Ivermectin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary*; D009814:Oesophagostomiasis / Q000188:drug therapy / Q000662:veterinary; D009815:Oesophagostomum / Q000302:isolation & purification; D010270:Parasite Egg Count / Q000662:veterinary; D012532:Scabies / Q000188:drug therapy / Q000662:veterinary*; D012867:Skin / Q000469:parasitology; D013321:Strongyloides / Q000302:isolation & purification; D013322:Strongyloidiasis / Q000188:drug therapy / Q000662:veterinary; D013552:Swine; D013553:Swine Diseases / Q000188:drug therapy*; D013997:Time Factors; D014257:Trichuriasis / Q000188:drug therapy / Q000662:veterinary; D014258:Trichuris / Q000302:isolation & purification
chemical_list: D000871:Anthelmintics; D007559:Ivermectin; C084101:doramectin