Dermatitis herpetiformis and bullous pemphigoid: a developing association confirmed by immunoelectronmicroscopy.
We report a case of dermatitis herpetiformis associated with bullous pemphigoid in which the clinical, histopathological and immunopathological findings were corroborated by direct immunoelectronmicroscopy performed on normal and peri-lesional skin biopsies. Western immunoblotting detected the 180 kDa BPAG2 consistent with bullous pemphigoid. HLA-typing confirmed the DR3 DQ2 haplotype associated with dermatitis herpetiformis.
Setterfield
J
J
St John's Institute of Dermatology (UMDS), St Thomas' Hospital, London, U.K.
Bhogal
B
B
Black
M M
MM
McGibbon
D H
DH
D000368:Aged; D000369:Aged, 80 and over; D003874:Dermatitis Herpetiformis / Q000150:complications* / Q000276:immunology / Q000473:pathology; D006801:Humans; D008297:Male; D016253:Microscopy, Immunoelectron; D010391:Pemphigoid, Bullous / Q000150:complications* / Q000276:immunology / Q000473:pathology