title: Antimutagenic activity of caffeic acid and related compounds.
abstract: Effects of caffeic acid and chlorogenic acid on mutagenicity were studied using the Salmonella typhimurium system. These compounds had inhibitory effects on the mutagenicity of Trp-P-1 and Glu-P-2. Caffeic acid completely eliminated the mutagenicity induced by activated Glu-P-2. Some compounds analogous to caffeic acid, such as cinnamic acid, coumaric acid, and ferulic acid, also significantly decreased the mutagenicity of Glu-P-2.
authors.affiliation: Laboratory of Food Science, Faculty of Education, Yamaguchi University, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Yamada
authors.forename: Y
authors.initials: Y
authors.lastname: Tomita
mesh_terms: D016587:Antimutagenic Agents / Q000494:pharmacology*; D002109:Caffeic Acids / Q000494:pharmacology*; D002726:Chlorogenic Acid / Q000494:pharmacology*; D009152:Mutagenicity Tests; D009153:Mutagens / Q000633:toxicity
chemical_list: D016587:Antimutagenic Agents; D002109:Caffeic Acids; D009153:Mutagens; D002726:Chlorogenic Acid; C040048:caffeic acid