title: Distraction osteogenesis to widen the mandible.
abstract: The purpose of this investigation was to elucidate the biology of distraction osteogenesis during mandibular widening. Midsymphyseal vertical interdental osteotomies were performed in nine Macaca mulatta monkeys. After a latency period a tooth-borne appliance was activated at a rate of 0.5 mm twice a day for 7-10 days. The appliance was then stabilized for a period of 4 or 8 weeks. The distraction gap at the inferior portion of the symphysis was bridged completely by new bony trabeculae. Bone formation in the interdental area was apparently related to the surgical technique. Newly formed bony trabeculae were oriented parallel to the direction of distraction. The location of the osteotomy site with an adequate margin of alveolar bone contiguous with the adjacent teeth was necessary for the induction of the distraction osteogenesis. Disproportional movement between superior and inferior portions of the distracted segments was noted.
authors.affiliation: Department of Oral Maxillofacial Surgery, Baylor College of Dentistry, Dallas, Texas 75266-0677, USA.
authors.forename: W H
authors.initials: WH
authors.lastname: Bell
authors.forename: R P
authors.initials: RP
authors.lastname: Harper
authors.forename: M
authors.initials: M
authors.lastname: Gonzalez
authors.forename: A M
authors.initials: AM
authors.lastname: Cherkashin
authors.forename: M L
authors.initials: ML
authors.lastname: Samchukov
mesh_terms: D000539:Alveolar Process / Q000000981:diagnostic imaging / Q000473:pathology / Q000502:physiology / Q000601:surgery; D000704:Analysis of Variance; D000818:Animals; D001695:Biology; D001852:Bone Lengthening / Q000295:instrumentation / Q000379:methods*; D001861:Bone Regeneration; D003481:Cuspid; D004867:Equipment Design; D007180:Incisor; D016018:Least-Squares Analysis; D008253:Macaca mulatta; D008334:Mandible / Q000000981:diagnostic imaging / Q000473:pathology / Q000502:physiology / Q000601:surgery*; D010012:Osteogenesis; D010027:Osteotomy / Q000379:methods; D010513:Periodontal Ligament / Q000000981:diagnostic imaging / Q000473:pathology / Q000502:physiology / Q000601:surgery; D011859:Radiography; D014092:Tooth Root