The role of azole antifungal agents for systemic antifungal therapy.
Although amphotericin B remains the cornerstone of antifungal drug therapy, fluconazole and itraconazole have been found useful for long-term maintenance or prophylactic regimens. This article reviews characteristics of fluconazole and itraconazole and compares them with ketoconazole and amphotericin B.
Lee
Y P
YP
Cleveland Clinic, OH 44195, USA.
Goldman
M
M
D000666:Amphotericin B / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D016527:Drug Costs; D004347:Drug Interactions; D004352:Drug Resistance, Microbial; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use*; D007654:Ketoconazole / Q000627:therapeutic use*
D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B; D015725:Fluconazole; D007654:Ketoconazole