Src family protein tyrosine kinases: cooperating with growth factor and adhesion signaling pathways.
The Src family of protein tyrosine kinases functionally interacts with several receptor and nonreceptor protein tyrosine kinases. Recent developments show that Src family kinases may cooperate with the epidermal growth factor and platelet-derived growth factor receptors and the integrin-linked focal adhesion kinase to diversify signals that regulate growth and cell movement.
Parsons
J T
JT
Department of Microbiology, Health Sciences Center, University of Virginia, Charlottesville, VA 22908, USA. jtp@Virginia.EDU
Parsons
S J
SJ
D000818:Animals; D002448:Cell Adhesion / Q000502:physiology*; D015815:Cell Adhesion Molecules / Q000378:metabolism; D002465:Cell Movement; D004789:Enzyme Activation; D005109:Extracellular Matrix / Q000378:metabolism; D051417:Focal Adhesion Kinase 1; D051416:Focal Adhesion Protein-Tyrosine Kinases; D006133:Growth Substances / Q000378:metabolism*; D006801:Humans; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D015398:Signal Transduction; D019061:src-Family Kinases / Q000378:metabolism*
D015815:Cell Adhesion Molecules; D006133:Growth Substances; D011505:Protein-Tyrosine Kinases; D051417:Focal Adhesion Kinase 1; D051416:Focal Adhesion Protein-Tyrosine Kinases; C496050:PTK2 protein, human; D019061:src-Family Kinases