title: Design and synthesis of substrate-derived n-acylaminoalkyl 2-pyridyl disulphides as probes of cysteine proteinase mechanism.
authors.affiliation: Dept. of Biochemistry, Queen Mary and Westfield College, University of London, UK.
authors.forename: K
authors.initials: K
authors.lastname: Brocklehurst
authors.forename: E W
authors.initials: EW
authors.lastname: Thomas
authors.forename: C
authors.initials: C
authors.lastname: Verma
authors.forename: M
authors.initials: M
authors.lastname: Patel
authors.forename: S K
authors.initials: SK
authors.lastname: Sreedharan
mesh_terms: D001665:Binding Sites; D003545:Cysteine; D003546:Cysteine Endopeptidases / Q000378:metabolism*; D004220:Disulfides / Q000138:chemical synthesis / Q000494:pharmacology*; D015195:Drug Design; D006639:Histidine; D006860:Hydrogen Bonding; D008956:Models, Chemical; D011725:Pyridines / Q000138:chemical synthesis / Q000494:pharmacology*; D055672:Static Electricity; D013329:Structure-Activity Relationship; D013379:Substrate Specificity
chemical_list: D004220:Disulfides; D011725:Pyridines; D006639:Histidine; D003546:Cysteine Endopeptidases; D003545:Cysteine