Laryngeal radionecrosis versus recurrent cancer.
This article reviews the nature, pathogenesis, and clinical grading system of laryngeal radionecrosis. The differentiation of radiation-induced soft-tissue complications from recurrent cancer can be a difficult clinical dilemma. Conventional imagery and even biopsy results are frequently equivocal. A treatment-interventional algorithmic approach to the problem patient is presented, and the role of positron emission tomographic scanning in making this differentiation is discussed.
McGuirt
W F
WF
Department of Otolaryngology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina 27157-1034, USA.
D003937:Diagnosis, Differential; D006801:Humans; D007818:Laryngeal Diseases / Q000175:diagnosis*; D007822:Laryngeal Neoplasms / Q000532:radiotherapy*; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis*; D011832:Radiation Injuries / Q000175:diagnosis*; D011878:Radiotherapy / Q000009:adverse effects*; D014055:Tomography, Emission-Computed