title: Transient brain activity used in magnetic resonance imaging to detect functional areas.
abstract: Functional areas were detected with short stimuli eliciting transient brain activity using the method of 'transient' regions of interest (ROIs) and functional magnetic resonance imaging (fMRI). This method was validated by comparing the results with sustainedly activated areas identified conventionally. Eighty-eight and 89% of the total areas of transient ROIs derived from 0.2 and 2 s stimulation, respectively, were identified at 5-7 s and 5-9 s, respectively, after stimulus onset. Eighty-eight and 76%, respectively, of these areas overlapped 'conventional' ROIs derived from 20 s stimulation. These results suggest that the delineation of transient ROIs, by targeting a period approximately 7 s after transient neural activity, can be useful for fMRI studies of cognitive functions.
authors.affiliation: Department of Physiology, University of Tokyo School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Konishi
authors.forename: R
authors.initials: R
authors.lastname: Yoneyama
authors.forename: H
authors.initials: H
authors.lastname: Itagaki
authors.forename: I
authors.initials: I
authors.lastname: Uchida
authors.forename: K
authors.initials: K
authors.lastname: Nakajima
authors.forename: H
authors.initials: H
authors.lastname: Kato
authors.forename: K
authors.initials: K
authors.lastname: Okajima
authors.forename: H
authors.initials: H
authors.lastname: Koizumi
authors.forename: Y
authors.initials: Y
authors.lastname: Miyashita
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology*; D002533:Cerebral Angiography; D006801:Humans; D007091:Image Processing, Computer-Assisted; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D010775:Photic Stimulation; D014793:Visual Cortex / Q000033:anatomy & histology / Q000502:physiology