title: The mydriatic effect of tropicamide and its diagnostic use in Alzheimer's disease.
abstract: The mydriatic effect of topically administered tropicamide was investigated as a possible diagnostic indicator for Alzheimer's disease. Although an initial series seemed to show a correlation between hypersensitivity to tropicamide and intellectual impairment, subsequent testing showed a greater inter- and intra-individual variation than that between the normal group and the group of patients with intellectual impairment. This procedure seems, therefore, to lack sufficient specificity to be useful for such a diagnostic purpose.
authors.affiliation: Department of Ophthalmology, University of Vienna, Austria. andreas.Reitner@akh-wien.ac.at
authors.forename: A
authors.initials: A
authors.lastname: Reitner
authors.forename: I
authors.initials: I
authors.lastname: Baumgartner
authors.forename: C
authors.initials: C
authors.lastname: Thuile
authors.forename: R
authors.initials: R
authors.lastname: Baradaran Dilmaghani
authors.forename: E
authors.initials: E
authors.lastname: Ergun
authors.forename: S
authors.initials: S
authors.lastname: Kaminski
authors.forename: J
authors.initials: J
authors.lastname: Lukas
authors.forename: P
authors.initials: P
authors.lastname: Dal Bianco
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis*; D003315:Cornea / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D009184:Mydriatics / Q000494:pharmacology; D011680:Pupil / Q000187:drug effects; D015203:Reproducibility of Results; D014331:Tropicamide / Q000494:pharmacology
chemical_list: D009184:Mydriatics; D014331:Tropicamide