title: Prone positioning decreases episodes of hypoxemia in extremely low birth weight infants (1000 grams or less) with chronic lung disease.
abstract: Extremely low birth weight infants with chronic lung disease (CLD) have frequent episodes of desaturation (hypoxemia). We quantified oxygenation and episodes of hypoxemia in 55 infants (birth weight < or = 1000 gm) with CLD in the supine versus prone position, for 1-hour time intervals. Oxygen saturation was measured with the Nellcor N-200 pulse oximeter and a computer program. Prone positioning increased oxygen saturation from 92.0% to 94.1% (p < 0.001) and significantly decreased episodes of hypoxemia to oxygen saturation levels of less than 90%, 85%, and 80% (p < 0.001). Our findings support prone positioning for the extremely low birth weight infant with CLD in an intensive care setting.
authors.affiliation: Department of Pediatrics, Sacred Heart Hospital, University of Florida, Pensacola 32504, USA.
authors.forename: C
authors.initials: C
authors.lastname: McEvoy
authors.forename: M E
authors.initials: ME
authors.lastname: Mendoza
authors.forename: S
authors.initials: S
authors.lastname: Bowling
authors.forename: V
authors.initials: V
authors.lastname: Hewlett
authors.forename: S
authors.initials: S
authors.lastname: Sardesai
authors.forename: M
authors.initials: M
authors.lastname: Durand
mesh_terms: D002908:Chronic Disease; D018592:Cross-Over Studies; D006801:Humans; D000860:Hypoxia / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight / Q000097:blood*; D008171:Lung Diseases / Q000097:blood / Q000150:complications*; D008991:Monitoring, Physiologic; D010092:Oximetry / Q000706:statistics & numerical data; D010100:Oxygen / Q000097:blood; D016684:Prone Position; D011446:Prospective Studies; D018709:Statistics, Nonparametric; D016683:Supine Position
chemical_list: D010100:Oxygen