title: Long-term clinical follow-up after directional coronary atherectomy.
abstract: Although several studies have been done to assess the safety, efficacy, and angiographic restenosis rates of directional coronary atherectomy (DCA), there have been no studies to document the need for repeat revascularization of the target vessel based purely on recurrence of symptoms. To answer this question, clinical and angiographic data were obtained for 187 consecutive patients undergoing this procedure on a native coronary artery utilizing a lesion specific approach in a referral hospital. Most of the patients had anginal symptoms that were not well controlled with medical therapy. The decision to perform DCA was based on the lesion characteristics (i.e., eccentric, ulcerated, or irregular discrete lesions in a large epicardial vessel). The procedure was successful in 96% of patients. In-hospital major complications were seen in 6 patients (3%) including acute myocardial infarction in 3 (1.5%) and emergency coronary artery bypass surgery in the other 3 (1.5%). There were no deaths. Among 141 consecutive successful patients on whom the procedure was performed between January 1992 and June 1994, 128 (91%) were contacted. At 6 months, revascularization was required in 20 patients for recurrent anginal symptoms, and there were no deaths or myocardial infarctions. The clinical restenosis rate, therefore, was 15.6%. At long-term follow-up (25 +/- 9 months), revascularization was performed in 3 more patients. One patient had a myocardial infarction and 3 patients died of noncardiac causes. Among those without clinical restenosis, 83% patients were asymptomatic and the rest had infrequent chest pains effectively managed with medications. The patients in the study group were using an average of 1.2 cardiac medications. Quality of life improved in 74% of the patients. Thus, in this study utilizing a lesion specific approach, the success rate for DCA was comparable to the published trials and in-hospital complications were few. The long-term clinical outcome was favorable with a low rate of clinical restenosis requiring repeat revascularization.
authors.affiliation: Regional Cardiac Catheterization Laboratory, Kaiser Permanente Medical Center, Los Angeles, California 90027, USA.
authors.forename: K S
authors.initials: KS
authors.lastname: Grewal
authors.forename: M B
authors.initials: MB
authors.lastname: Jorgensen
authors.forename: J T
authors.initials: JT
authors.lastname: Diesto
authors.forename: P W
authors.initials: PW
authors.lastname: Mansukhani
authors.forename: V J
authors.initials: VJ
authors.lastname: Aharonian
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000188:drug therapy / Q000601:surgery; D017225:Atherectomy, Coronary / Q000009:adverse effects; D017023:Coronary Angiography; D001026:Coronary Artery Bypass; D003324:Coronary Artery Disease / Q000601:surgery; D003327:Coronary Disease / Q000601:surgery; D003331:Coronary Vessels / Q000601:surgery; D004630:Emergencies; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology; D011788:Quality of Life; D012008:Recurrence; D012086:Reoperation; D012449:Safety; D015996:Survival Rate; D016896:Treatment Outcome