Axon guidance: netrin receptors are revealed.
Netrins are molecules that guide growing axons and that are strikingly similar in sequence and in function in flies, nematodes and vertebrates. Now, members of a family of netrin receptors have been identified in all three animal groups and shown to have crucial, conserved roles in axon navigation.
Guthrie
S
S
Department of Developmental Neurobiology, UMDS, Guy's Hospital, London SE1 9RT, UK.
D000818:Animals; D001369:Axons / Q000502:physiology*; D004330:Drosophila / Q000502:physiology; D009414:Nerve Growth Factors / Q000502:physiology*; D000075388:Netrin-1; D000075385:Netrins; D051381:Rats; D011956:Receptors, Cell Surface / Q000502:physiology*; D025521:Tumor Suppressor Proteins
D009414:Nerve Growth Factors; D000075385:Netrins; D011956:Receptors, Cell Surface; D025521:Tumor Suppressor Proteins; D000075388:Netrin-1; C088894:netrin-2