Synthesis, chemical solvolytic stability and preliminary biological evaluation of (+/-)-N-Boc-CPzI: a pyrazole analog of the left-hand segment of the antitumor agent CC-1065.
Baraldi
P G
PG
Dipartimento di Scienze Farmaceutiche, Università di Ferrara, Italy.
Cacciari
B
B
Pineda de las Infantas
M J
MJ
Romagnoli
R
R
Spalluto
G
G
Cozzi
P
P
Mongelli
N
N
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000138:chemical synthesis* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D000080890:Duocarmycins; D007211:Indoles; D007933:Leucomycins / Q000737:chemistry*; D007939:Leukemia L1210 / Q000188:drug therapy; D011720:Pyrazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D000903:Antibiotics, Antineoplastic; D000080890:Duocarmycins; D007211:Indoles; D007933:Leucomycins; C104542:N-Boc-CPzI; D011720:Pyrazoles; C018782:CC 1065