title: [Sarcomatoid renal carcinoma].
abstract: Study of 250 pieces from nephrectomies performed in our service due to renal carcinoma, 10 (4%) of which where of the sarcomatoid histological variant. In 2 of the 10 cases, tumour was confined within the renal capsule at the time of surgery. These were the only cases where no disease progression was seen after treatment. A survival study using the Kaplan-Meter method was conducted. Median survival of patients with sarcomatoid pattern was 6 months, showing a significant difference with that obtained in other histological patterns. DNA content of tumoral cells was assessed by flow cytometry, which displayed a diploid pattern in 7 patients and aneuploid in 3. The 2 cases with no disease progression were diploid. We conducted nuclear cytomorphometry studies which showed significant differences in the mean nuclear perimeter between progressive and non-progressive tumours.
authors.affiliation: Servicio de Urología, Hospital Universitario La Fe, Valencia.
authors.forename: J M
authors.initials: JM
authors.lastname: Martinez Jabaloyas
authors.forename: J L
authors.initials: JL
authors.lastname: Ruiz Cerdá
authors.forename: S
authors.initials: S
authors.lastname: Sanz Chinesta
authors.forename: J F
authors.initials: JF
authors.lastname: Morera Martínez
authors.forename: J L
authors.initials: JL
authors.lastname: Pontones Moreno
authors.forename: A
authors.initials: A
authors.lastname: Jiménez Sánchez
authors.forename: J F
authors.initials: JF
authors.lastname: Jiménez Cruz
mesh_terms: D000328:Adult; D002277:Carcinoma / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008297:Male; D012509:Sarcoma / Q000473:pathology*
vernacular_title: Carcinoma renal sarcomatoide.