title: Absence of ANCA in Mexican patients with Takayasu's arteritis.
abstract: Antineutrophil cytoplasmic autoantibodies (ANCA) were sought in 43 sera from 39 Mexican patients with typical Takayasu's arteritis (TA), (5 with active and 34 with inactive disease), and in a comparative group comprising 50 sera. Results were negative in all cases. This suggests that ANCA are not a serologic feature in TA per se, even during its active stage. ANCA positivity in TA, when present, may be a non-related phenomenon and probably identifies a subset of patients with atypical forms of TA or a polyangiitis overlap syndrome.
authors.affiliation: Department of Pathology, Instituto Nacional de Cardiologia Ignacio Chávez, Mexico City, México.
authors.forename: R
authors.initials: R
authors.lastname: García-Torres
authors.forename: L H
authors.initials: LH
authors.lastname: Noël
authors.forename: P A
authors.initials: PA
authors.lastname: Reyes
authors.forename: O L
authors.initials: OL
authors.lastname: Vera
authors.forename: M C
authors.initials: MC
authors.lastname: Amigo
authors.forename: L H
authors.initials: LH
authors.lastname: Silveira
authors.forename: C
authors.initials: C
authors.lastname: Pineda
mesh_terms: D000328:Adult; D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008800:Mexico; D015995:Prevalence; D013625:Takayasu Arteritis / Q000097:blood / Q000276:immunology* / Q000473:pathology
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic