Granulosin, a new chromone from Galipea granulosa.
A novel chromone, granulosin (1), has been isolated from the bark of Galipea granulosa. The extract of the bark, as well as granulosin (1), exhibited lethality in the brine shrimp test. The structure of granulosin (1) as 2-propyl-7,8-(methylenedioxy)chromone was established via spectroscopic analysis.
Lpez
J A
JA
Instituto de Investigaciones Farmaceuticas (INIFAR), Facultad de Farmacia, Universidad de Costa Rica, San Jos.
Barillas
W
W
Gomez-Laurito
J
J
Martin
G E
GE
Al-Rehaily
A J
AJ
Zemaitis
M A
MA
Schiff
P L
PL
D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001156:Artemia; D002867:Chromones / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D009682:Magnetic Resonance Spectroscopy; D019441:Plant Epidermis / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D013020:South America; D013056:Spectrophotometry, Ultraviolet
D000970:Antineoplastic Agents; D002867:Chromones; C104550:granulosin