Spirometric nomograms for normal children and adolescents in Puerto Rico.
OBJECTIVE
The use of spirometric reference values specific to the population being tested is preferable. A study carried out in Puerto Rico is used here to develop nomograms for normal children and adolescents based on age and height, two variables that have been found to be good predictors of pulmonary function.


METHODS
The data for healthy individuals aged 5 to 18 were extracted (108 girls and 107 boys) from a larger study of spirometric measurements collected on 4527 individuals attending medical services in Puerto Rico. Several models were tested for the prediction of FEV1, FVC and the ratio FEV1/FVC. The best models were selected for each gender, and nomograms were developed showing the fifth, twenty-fifth, fiftieth, seventy-fifth, and ninety-fifth percentile of the predicted values according to age and height separately.


RESULTS
The best models were those using the logarithm of the pulmonary function and the cube of height (R2 = 0.79-0.81), and age without transformation (R2 = 0.73-0.77). Corresponding nomograms were developed based on these models. The ratio showed little variation for different ages and heights.


CONCLUSIONS
Pulmonary function can be efficiently predicted by age and height. Nomograms provide a simple way to use spirometric references that can be incorporated to clinical practice.
Chen-Mok
M
M
Department of Biostatistics, University of North Carolina at Chapel Hill, United States of America.
Bangdiwala
S I
SI
D000293:Adolescent; D000367:Age Factors; D001827:Body Height; D002648:Child; D002675:Child, Preschool; D005541:Forced Expiratory Volume; D006801:Humans; D011647:Puerto Rico; D012016:Reference Values; D013147:Spirometry / Q000592:standards*; D014797:Vital Capacity