title: Laparoscopic appendectomy-is it worthwhile? A prospective, randomized study in young women.
abstract: BACKGROUND
  Clinical diagnosis of acute appendicitis is most difficult in fertile-age women. In this patient group up to 50% of open appendectomies are negative for appendicitis. We conducted a randomized study to compare laparoscopic and open appendectomy in young female patients with suspected acute appendicitis.
  
  
  METHODS
  Fifty female patients between the ages of 16 and 40 years presenting with acute right lower abdominal pain were randomized, 25 to laparoscopy and 25 to an open appendectomy. Diagnostic accuracy, rate of negative appendectomies, safety, and final outcome were compared in the two groups.
  
  
  RESULTS
  Diagnosis was established in 96% of patients in the laparoscopic group and in 72% in the open group. There were 11 (44%) unnecessary appendectomies in the open group, but only one (4%) in the laparoscopic group (p < 0.0005).
  
  
  CONCLUSIONS
  In young women with right lower abdominal pain, laparoscopy can give precise diagnosis and reduce the rate of negative appendectomies.
authors.affiliation: Department of Surgery, Turku University Central Hospital, Kiinamyllynkatu 4-8, FIN-20520 Turku, Finland.
authors.forename: S
authors.initials: S
authors.lastname: Laine
authors.forename: A
authors.initials: A
authors.lastname: Rantala
authors.forename: R
authors.initials: R
authors.lastname: Gullichsen
authors.forename: J
authors.initials: J
authors.lastname: Ovaska
mesh_terms: D000293:Adolescent; D000328:Adult; D001062:Appendectomy / Q000379:methods*; D001064:Appendicitis / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D011183:Postoperative Complications / Q000503:physiopathology*; D011446:Prospective Studies; D016896:Treatment Outcome