Magnetic resonance imaging of temperature changes during interstitial microwave heating: a phantom study.
Changes in magnetic resonance (MR) signals during interstitial microwave heating are reported, and correlated with simultaneously acquired temperature readings from three fiber-optic probes implanted in a polyacrylamide gel phantom. The heating by a MR-compatible microwave antenna did not interfere with simultaneous MR image data acquisition. MR phase-difference images were obtained using a fast two-dimensional-gradient echo sequence. From these images the temperature-sensitive resonant frequency of the 1H nuclei was found to decrease approximately by 0.008 ppm/ degree C. The method and results presented here demonstrate that noninvasive MR-temperature imaging can be performed simultaneously with interstitial microwave thermal treatment.
Vitkin
I A
IA
Ontario Cancer Institute/Princess Margaret Hospital, University of Toronto, Canada.
Moriarty
J A
JA
Peters
R D
RD
Kolios
M C
MC
Gladman
A S
AS
Chen
J C
JC
Hinks
R S
RS
Hunt
J W
JW
Wilson
B C
BC
Easty
A C
AC
Bronskill
M J
MJ
Kucharczyk
W
W
Sherar
M D
MD
Henkelman
R M
RM
D055592:Biophysical Phenomena; D001703:Biophysics; D005336:Fiber Optic Technology; D006979:Hyperthermia, Induced; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D008872:Microwaves / Q000627:therapeutic use; D055100:Optical Fibers; D019047:Phantoms, Imaging; D013696:Temperature