title: Düsseldorf data on the PCR-based locus HumFES/FPS (human c-fes/fps proto oncogene).
abstract: This paper reports PCR-based genotype distribution and allele frequencies of the locus HumFES/FPS (human c-fes/fps proto oncogene). For this study 300 unrelated Caucasoids of German ancestry living in Düsseldorf were analyzed. Seven of the eight alleles previously described and fourteen of the corresponding thirty-six diploid genotypes were detected. The proportions of heterozygotes and homozygotes observed and expected and the parameters of forensic interest, e.g. the mean paternity exclusion chance, were calculated. No deviations from the Hardy-Weinberg equilibrium were observed. A preliminary German data base (3,238 individuals) was created by using the weighted arithmetical mean which included data from Düsseldorf.
authors.affiliation: Institute of Forensic Medicine, Heinrich-Heine-University, Düsseldorf, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Huckenbeck
authors.forename: K
authors.initials: K
authors.lastname: Demir
authors.forename: H G
authors.initials: HG
authors.lastname: Scheil
authors.forename: K W
authors.initials: KW
authors.lastname: Alt
authors.forename: W
authors.initials: W
authors.lastname: Bonte
mesh_terms: D000483:Alleles; D005787:Gene Frequency; D005858:Germany; D006801:Humans; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D011505:Protein-Tyrosine Kinases; D000090063:Proto-Oncogene Mas; D011518:Proto-Oncogene Proteins / Q000235:genetics*
chemical_list: C000715470:MAS1 protein, human; D000090063:Proto-Oncogene Mas; D011518:Proto-Oncogene Proteins; C052602:proto-oncogene protein c-fes-fps; D011505:Protein-Tyrosine Kinases