title: [Clinical evaluation of the effectiveness of radiotherapy for vaginal tumors].
abstract: The report deals with the data on 133 patients with primary tumors of the vagina treated with both combined (tele- and contact gamma therapy) and contact treatment using low, medium and high dosage. The following radiobiological models were used for evaluating and comparing responses of normal tissue: time-dose fractionation, cumulative radiation effect and linear-square law model referred to as the "extrapolation-related dose of response". The results suggest that combined radiotherapy using high-dose contact treatment be recommended for localized stage I-II tumors while cases of stage III tumor should receive only combined radiotherapy provided brachitherapy uses modern radiation equipment which will assure a minimal gap between the nominal and actual characteristics of irradiation.
authors.forename: S V
authors.initials: SV
authors.lastname: Kanaev
authors.forename: V G
authors.initials: VG
authors.lastname: Turkevich
mesh_terms: D001918:Brachytherapy; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D011878:Radiotherapy / Q000379:methods; D011879:Radiotherapy Dosage; D016019:Survival Analysis; D013997:Time Factors; D016896:Treatment Outcome; D014625:Vaginal Neoplasms / Q000473:pathology / Q000532:radiotherapy*
vernacular_title: Klinicheskaia otsenka éffektivnosti luchevogo lecheniia raka vlagalishcha.