title: Allele frequency distributions at seven DNA hypervariable loci in a population sample from Calabria (southern Italy).
abstract: Genotype and allele frequencies at seven Variable Number of Tandem Repeats (VNTR) loci currently used for forensic purposes have been estimated in a population sample from Calabria (south Italy). DNA target regions relevant to four microsatellites (THO.1; REN.4; D12S67; DYS19) and three minisatellites (D1S80; 3'APOB; TPO.10) were amplified by Polymerase Chain Reaction (PCR) and analysed by electrophoresis and ethidium bromide or silver staining. For all loci, the observed genotypes were found to be in agreement with those expected by the Hardy-Weinberg equilibrium. Data on allele frequencies were in line with those found in sample groups from northern or central Italy, tested for some of the above polymorphisms.
authors.affiliation: Cell Biology Department, University of Calabria, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Rose
authors.forename: M
authors.initials: M
authors.lastname: De Luca
authors.forename: E
authors.initials: E
authors.lastname: Falcone
authors.forename: P
authors.initials: P
authors.lastname: Spadafora
authors.forename: G
authors.initials: G
authors.lastname: Carrieri
authors.forename: G
authors.initials: G
authors.lastname: De Benedictis
mesh_terms: D000293:Adolescent; D000328:Adult; D000483:Alleles; D001483:Base Sequence; D002648:Child; D004276:DNA, Satellite; D005260:Female; D005787:Gene Frequency; D005838:Genotype; D006801:Humans; D007558:Italy; D008297:Male; D018895:Microsatellite Repeats; D008875:Middle Aged; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic
chemical_list: D004276:DNA, Satellite