Immunology: what is the proximal cause of inflammation?
Knockout mice lacking either the antibody constant region (Fc) receptor or the substance P receptor fail to produce a model inflammatory response, implicating these two receptors in early events of inflammation.
Walport
M J
MJ
Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London W12 0NN, UK. mwalport@rpms.ac.uk
Taylor
P R
PR
D000818:Animals; D001183:Arthus Reaction / Q000503:physiopathology; D006801:Humans; D007249:Inflammation / Q000503:physiopathology*; D051379:Mice; D018345:Mice, Knockout; D011961:Receptors, Fc / Q000235:genetics / Q000502:physiology; D018040:Receptors, Neurokinin-1 / Q000235:genetics / Q000502:physiology
D011961:Receptors, Fc; D018040:Receptors, Neurokinin-1