title: Does physical exercise influence the occurrence of epileptiform EEG discharges in children?
abstract: OBJECTIVE
  To determine if, and how, epileptiform EEG discharges in children were influenced by physical exercise.
  
  
  METHODS
  Twenty-six children with intractable partial and generalized epilepsy exercised during video-telemetry recording, aiming at exhaustion after approximately 10 min.
  
  
  RESULTS
  During the exercise, epileptiform discharges decreased in 20 of 26 children (17 children had at least 25% reduction) and showed a rebound increase after the exercise (17 of 26 children) compared to baseline conditions. This exercise-induced reduction in epileptiform discharges reached statistical significance only in the 16 patients with localization-related epilepsy. Five patients showed an atypical EEG response to exercise with either unchanged or increased epileptiform activity while exercising. As compared to the other patients, these 5 children had experienced frequent clinical seizures during or immediately after exercise in their leisure time.
  
  
  CONCLUSIONS
  In the majority of the tested children, epileptiform EEG discharges decreased during exercise. "Exercise-EEG" may be a helpful diagnostic tool to identify patients who are disposed to have exercise-induced seizures.
authors.affiliation: The National Center for Epilepsy, Sandvika, Norway.
authors.forename: K O
authors.initials: KO
authors.lastname: Nakken
authors.forename: A
authors.initials: A
authors.lastname: Løyning
authors.forename: T
authors.initials: T
authors.lastname: Løyning
authors.forename: G
authors.initials: G
authors.lastname: Gløersen
authors.forename: P G
authors.initials: PG
authors.lastname: Larsson
mesh_terms: D000293:Adolescent; D002648:Child; D004569:Electroencephalography; D004827:Epilepsy / Q000453:epidemiology* / Q000503:physiopathology*; D015444:Exercise / Q000502:physiology; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D012307:Risk Factors