[The use of a new method for determining the ratio of the glomerular filtration rate to circulating plasma volume in patients with arterial hypertension].
Renal scintigrams with 99Tc-DTPA were analysed retrospectively in 19 patients with essential hypertension. Glomerular filtration rate (GFR) was measured by Gates technique. Ratio GFR to plasma volume (PV) was quantified by A. M. Peters' technique (1994). PV was calculated as the relation of these two indices. Total GFR in hypertensive patients widely ranged (from 76.8 ml/min to 165.7 ml/min). Three groups were selected taking into account hypertension duration: patients with decreased, normal and increased values of basal GFR. The severity of hypertension did not affect the GFR, but showed positive and strong correlation with PV (r = 0.91; p < 0.05). GFR/PV was decreased in hypertensive patients. Factors affecting the GFR in hypertensive subjects are discussed.
Koniaeva
E B
EB
Usov
V Iu
VIu
Krivonogov
N G
NG
Mordovin
V F
VF
D000328:Adult; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D006973:Hypertension / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010953:Plasma Volume; D011866:Radioisotope Renography / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D012189:Retrospective Studies; D016284:Technetium Tc 99m Pentetate
D016284:Technetium Tc 99m Pentetate
Primenenie novogo metoda opredeleniia otnosheniia skorosti klubochkovoĭ fil'tratsii k ob''emu tsirkuliruiushcheĭ plazmy u bol'nykh arterial'noĭ gipertonieĭ.