Pretreatment with aspirin and ticlopidine confers lower thrombogenic potential of radiofrequency catheter ablation.
In the present study we pretreated 31 patients undergoing radiofrequency catheter ablation (RFA) with combined aspirin and ticlopidine for 3 days before the procedure, whereas 37 patients did not receive pretreatment. D-dimer levels reflecting the thrombogenic potential of RFA were significantly lower in the pretreated group at each stage before, during, and after the procedure, whereas there were no significant differences between the 2 groups in the number of RFA lesions or duration of the procedure.
Manolis
A S
AS
Onossis Cardiac Surgery Center, Athens, Greece.
Vassilikos
V
V
Maounis
T N
TN
Psarros
L
L
Melita-Manolis
H
H
Papatheou
D
D
Haliassos
A
A
Christopoulou-Cokkinou
V
V
Cokkinos
D V
DV
D000293:Adolescent; D000328:Adult; D000368:Aged; D001145:Arrhythmias, Cardiac / Q000601:surgery*; D001241:Aspirin / Q000627:therapeutic use*; D017115:Catheter Ablation / Q000009:adverse effects*; D002648:Child; D004594:Electrophysiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D013923:Thromboembolism / Q000209:etiology* / Q000517:prevention & control*; D013988:Ticlopidine / Q000627:therapeutic use*
D010975:Platelet Aggregation Inhibitors; D013988:Ticlopidine; D001241:Aspirin