Neurologic comorbidity and mania in old age.
This review focuses on the clear association of a wide range of neurological disorders with the clinical phenomenon of mania in old age. The nature of these neurologic disorders is described and discussed. The significance of this association in the context of premorbid vulnerability to mood disorders, late age of onset, and high mortality at follow-up is discussed and integrated into a comprehensive model for the understanding of mania in old age. The author outlines future research directions that may enhance our understanding of mania in old age, as well as in younger age groups.
Shulman
K I
KI
Department of Psychiatry University of Toronto, Ontario, Canada.
D000368:Aged / Q000523:psychology*; D001714:Bipolar Disorder / Q000150:complications / Q000523:psychology*; D015897:Comorbidity; D006801:Humans; D009422:Nervous System Diseases / Q000150:complications / Q000523:psychology*