title: [Brain uptake ratio as an index of cerebral blood flow obtained with 99mTc-ECD].
abstract: A new index of cerebral blood flow (brain uptake ratio, BUR) using 99mTc-ECD was developed and evaluated in 66 patients (132 cerebral hemispheres). BUR was calculated from brain count in anterior planar image (60-80 sec after injection of 99mTc-ECD) divided by the summation of the count of aortic arch during first transit of radionuclide. BUR correlated well with brain perfusion index (BPI) obtained with Patlak plot method (r = 0.960, p < 0.001). In conclusion, BUR is useful as a simple and non-invasive index reflecting cerebral blood flow.
authors.affiliation: Section of Nuclear Medicine, Noto General Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Miyazaki
authors.forename: S
authors.initials: S
authors.lastname: Kinuya
authors.forename: M
authors.initials: M
authors.lastname: Hashimoto
authors.forename: R
authors.initials: R
authors.lastname: Satake
authors.forename: H
authors.initials: H
authors.lastname: Inoue
authors.forename: J
authors.initials: J
authors.lastname: Shiozaki
authors.forename: M
authors.initials: M
authors.lastname: Takimoto
authors.forename: H
authors.initials: H
authors.lastname: Itoh
authors.forename: J
authors.initials: J
authors.lastname: Taki
authors.forename: N
authors.initials: N
authors.lastname: Tonami
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001812:Blood-Brain Barrier; D001921:Brain / Q000000981:diagnostic imaging* / Q000378:metabolism*; D002560:Cerebrovascular Circulation; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging / Q000503:physiopathology; D003545:Cysteine / Q000031:analogs & derivatives*; D006801:Humans; D008863:Microspheres; D008875:Middle Aged; D015609:Organotechnetium Compounds / Q000493:pharmacokinetics; D010477:Perfusion; D011877:Radionuclide Imaging
chemical_list: D015609:Organotechnetium Compounds; C059659:technetium Tc 99m bicisate; D003545:Cysteine