Effects of Panax Ginseng C.A. Meyer saponins on male fertility.
Sixty-six patients have been treated with Panax Ginseng C.A. Meyer extract, of whom 30 oligoastenospermic sine causa (group A), 16 oligoastenospermic with idiopathic varicocele (group B). Twenty age-matched volunteers were used as controls (group C). Use of Panax Ginseng extract showed an increase in spermatozoa number/ml and progressive oscillating motility, an increase in plasma total and free testosterone, DHT, FSH and LH levels, but a decrease in mean PRL. It is suggested that ginsenosides may have an effect at different levels of the hypothalamus-pituitary-testis axis.
Salvati
G
G
V Clinica Medica, University of Rome La Sapienza, Italy.
Genovesi
G
G
Marcellini
L
L
Paolini
P
P
De Nuccio
I
I
Pepe
M
M
Re
M
M
D000328:Adult; D005298:Fertility / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D005894:Panax; D010936:Plant Extracts / Q000627:therapeutic use*; D010946:Plants, Medicinal; D012503:Saponins / Q000627:therapeutic use*
D010936:Plant Extracts; D012503:Saponins