Control of cerebral and ocular blood flow autoregulation in neonates.
Several factors have been implicated in the regulation of cerebral and ocular vasomotor tone in the newborn: the interrelationship between prostanoids, NO, and other vasoactive mediators remains a subject of interest and active investigation. Pharmacologic modulation may provide new treatment modalities for diseases of the newborn that are mostly hemodynamic and vascular in nature.
Hardy
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Department of Pediatrics, University of Montreal, Quebec, Canada.
Varma
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D002543:Cerebral Hemorrhage / Q000188:drug therapy* / Q000503:physiopathology; D002552:Cerebral Ventricles; D002560:Cerebrovascular Circulation / Q000187:drug effects*; D005123:Eye / Q000098:blood supply* / Q000294:innervation; D006706:Homeostasis / Q000187:drug effects*; D006801:Humans; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000188:drug therapy* / Q000503:physiopathology; D009569:Nitric Oxide / Q000502:physiology; D011453:Prostaglandins / Q000502:physiology; D012178:Retinopathy of Prematurity / Q000188:drug therapy* / Q000503:physiopathology
D011453:Prostaglandins; D009569:Nitric Oxide