title: Functional improvement after volume reduction: sternotomy versus videoendoscopic approach.
abstract: BACKGROUND
  Volume reduction has been proved to increase ventilatory mechanics in diffuse, nonbullous lung emphysema. However, the best approach is still controversial.
  
  
  METHODS
  We retrospectively compared the perioperative data of and functional results in 15 patients having sternotomy (group I) with those of 15 patients having a videoendoscopic approach (group II).
  
  
  RESULTS
  The 30-day mortality was 2 patients in group I and 1 patient in group II. Mean duration of chest tube drainage was 8.7 +/- 1.8 days and 8.0 +/- 1.9 days and mean hospital stay, 12.3 +/- 1.9 and 12.5 +/- 2.1 days in groups I and II, respectively. Work of breathing decreased from 1.89 +/- 0.33 J/L and 1.76 +/- 0.22 J/L preoperatively to 0.75 +/- 0.06 J/L and 0.8 +/- 0.06 J/L (p < 0.01 and p < 0.05, respectively) after 3 months; and intrinsic positive end-expiratory pressure decreased from 7.15 +/- 1.31 cm H2O and 6.24 +/- 1.33 cm H2O to preoperatively 0.79 +/- 0.46 cm H2O and 1.13 +/- 0.44 cm H2O (p < 0.005 and p < 0.01, respectively) after 3 months in groups I and II, respectively. Forced expiratory volume in 1 second increased from preoperative values of 21.6% +/- 2.9% and 25.3% +/- 2.4% of predicted to 34.5% +/- 5.0% and 40.9% +/- 7.5% of predicted after 3 months (p < 0.05 in both groups) in groups I and II, respectively.
  
  
  CONCLUSIONS
  Both surgical approaches resulted in similar substantial improvement in lung function and physical fitness. The incidence of air leakage, the duration of chest tube drainage, and the hospital stay were the same for both procedures.
authors.affiliation: Department of Cardiothoracic Surgery, University of Vienna, Austria.
authors.forename: W
authors.initials: W
authors.lastname: Wisser
authors.forename: E
authors.initials: E
authors.lastname: Tschernko
authors.forename: O
authors.initials: O
authors.lastname: Senbaklavaci
authors.forename: M
authors.initials: M
authors.lastname: Kontrus
authors.forename: T
authors.initials: T
authors.lastname: Wanke
authors.forename: E
authors.initials: E
authors.lastname: Wolner
authors.forename: W
authors.initials: W
authors.lastname: Klepetko
mesh_terms: D016022:Case-Control Studies; D015505:Chest Tubes; D004417:Dyspnea / Q000503:physiopathology; D004724:Endoscopy; D017079:Exercise Tolerance; D005260:Female; D006801:Humans; D007902:Length of Stay / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy / Q000379:methods*; D011656:Pulmonary Emphysema / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D012129:Respiratory Function Tests; D012189:Retrospective Studies; D013249:Sternum / Q000601:surgery; D013997:Time Factors