title: [The evaluation of the detoxication function of the kidneys by the clearance of middle molecules].
abstract: The detoxifying function of the kidneys was examined in 56 patients with renal diseases. The function was assessed from the clearance of medium-mass molecules in relation to the total water content in the body. Medium-mass molecules in the serum and urine were assessed by the method based on direct UV spectrophotometry. A correlation has been revealed between the content of medium-mass molecules, serum creatinine, clearance of creatinine, and the detoxifying function of the kidneys. The method is simple, reliable, and does not require expensive reagents.
authors.forename: A M
authors.initials: AM
authors.lastname: Shutov
authors.forename: P A
authors.initials: PA
authors.lastname: Prokaeva
authors.forename: S V
authors.initials: SV
authors.lastname: Zhelezniakova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001834:Body Water / Q000737:chemistry; D005260:Female; D006801:Humans; D007668:Kidney / Q000378:metabolism*; D007674:Kidney Diseases / Q000378:metabolism; D007677:Kidney Function Tests / Q000379:methods / Q000706:statistics & numerical data; D008297:Male; D008657:Metabolic Clearance Rate; D008875:Middle Aged; D008970:Molecular Weight; D010455:Peptides / Q000032:analysis / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet
chemical_list: D010455:Peptides
vernacular_title: Otsenka detoksikatsionnoĭ funktsii pochek po klirensu srednikh molekul.