title: Salt-induced changes in lipid composition and ethanol tolerance in Saccharomyces cerevisiae.
abstract: The effect of salt stress on lipid composition and its relationship with ethanol tolerance in Saccharomyces cerevisiae was studied. Amounts of phospholipids as well as that of sterols decreased, whereas that of protein and glycolipids increased with increasing salt concentration. Relative proportion of amino phospholipids (phosphatidylethanolamine and phosphatidylserine) decreased, whereas that of phosphatidylcholine showed a reverse trend. Cells grown under increasing salt concentration were more resistant to ethanol-induced leakage of UV-absorbing substances, an index of ethanol endurance. Results showed an overlap between osmotolerance and ethanol tolerance in this strain.
authors.affiliation: Department of Biochemistry, Panjab University Chandigarh, India.
authors.forename: S C
authors.initials: SC
authors.lastname: Sharma
authors.forename: D
authors.initials: D
authors.lastname: Raj
authors.forename: M
authors.initials: M
authors.lastname: Forouzandeh
authors.forename: M P
authors.initials: MP
authors.lastname: Bansal
mesh_terms: D001709:Biotechnology; D000431:Ethanol / Q000494:pharmacology*; D005656:Fungal Proteins / Q000378:metabolism; D006017:Glycolipids / Q000378:metabolism; D050356:Lipid Metabolism; D008055:Lipids / Q000737:chemistry; D010743:Phospholipids / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000187:drug effects* / Q000378:metabolism*; D012965:Sodium Chloride / Q000494:pharmacology; D013261:Sterols / Q000378:metabolism
chemical_list: D005656:Fungal Proteins; D006017:Glycolipids; D008055:Lipids; D010743:Phospholipids; D013261:Sterols; D000431:Ethanol; D012965:Sodium Chloride