title: Characterization of the pH signal transduction pathway gene palA of Aspergillus nidulans and identification of possible homologs.
abstract: We have cloned the palA gene of Aspergillus nidulans, one of six genes participating in ambient pH signal transduction in a regulatory circuit mediating pH regulation of gene expression. The derived 798-residue PalA protein is 29.4% identical over its entire length to a hypothetical protein from the nematode Caenorhabditis elegans and also has possible yeast homologs.
authors.affiliation: Department of Infectious Diseases, Royal Postgraduate Medical School, London, United Kingdom.
authors.forename: S
authors.initials: S
authors.lastname: Negrete-Urtasun
authors.forename: S H
authors.initials: SH
authors.lastname: Denison
authors.forename: H N
authors.initials: HN
authors.lastname: Arst
mesh_terms: D000595:Amino Acid Sequence; D001233:Aspergillus nidulans / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D001483:Base Sequence; D003001:Cloning, Molecular; D005656:Fungal Proteins / Q000737:chemistry / Q000235:genetics* / Q000502:physiology; D015966:Gene Expression Regulation, Fungal; D005800:Genes, Fungal; D006863:Hydrogen-Ion Concentration; D008969:Molecular Sequence Data; D012331:RNA, Fungal / Q000235:genetics / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D016415:Sequence Alignment; D015398:Signal Transduction / Q000235:genetics*
chemical_list: D005656:Fungal Proteins; C104643:PALA protein, Emericella nidulans; D012331:RNA, Fungal; D012333:RNA, Messenger