title: Nitrous oxide does not increase vomiting after dental restorations in children.
abstract: The effect of nitrous oxide on postoperative vomiting was evaluated in 330 children who underwent outpatient dental restorations. There were two groups in this single-blind, randomized, controlled study. One group received nitrous oxide during their anesthetic, while the non-nitrous oxide group did not receive nitrous oxide at any time. Anesthesia was induced by inhalation with halothane or with propofol intravenously. The incidence of vomiting for 24 h after surgery was recorded. Overall, the incidence of vomiting was similar, with 30% of the control patients and 35% of the nitrous-treated patients vomiting after their anesthetic. However, in-hospital vomiting was less in the control group: 15% vs 24%, control versus nitrous oxide, P = 0.03. In conclusion, nitrous oxide does not alter postoperative vomiting after halothane anaesthesia for dental restorations in children.
authors.affiliation: Department of Anaesthesia, Children's Hospital of Eastern Ontario, Ottawa, Canada.
authors.forename: W M
authors.initials: WM
authors.lastname: Splinter
authors.forename: L
authors.initials: L
authors.lastname: Komocar
mesh_terms: D002648:Child; D002675:Child, Preschool; D003793:Dental Restoration, Permanent / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D009609:Nitrous Oxide / Q000009:adverse effects*; D011183:Postoperative Complications; D011292:Premedication; D014839:Vomiting / Q000139:chemically induced*
chemical_list: D009609:Nitrous Oxide