title: A chance SPECT study of ictal aphasia during simple partial seizures.
abstract: We report obtaining an ictal single photon emission computed tomographic (SPECT) scan in a right-handed 51-year-old man who had an astrocytoma in the left cerebral hemisphere and simple partial seizures characterized by aphasia. An epileptic seizure producing loss of speech and right-sided facial twitching occurred by chance during a SPECT scan. During the attack, he was unable to speak, but auditory comprehension and writing were intact. Ictal SPECT showed an area of increased perfusion in the left frontal cortex, with the area of highest perfusion involving the left frontal operculum to the inferior part of the left precentral gyrus. Interictal SPECT showed hypoperfusion in the same area. These SPECT findings suggest that the frontal operculum of the dominant hemisphere is one of the regions that can give rise to epileptic aphasia.
authors.affiliation: Department of Neuropsychiatry, Osaka Medical College, Takatsuki, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Sakai
authors.forename: M
authors.initials: M
authors.lastname: Hidari
authors.forename: M
authors.initials: M
authors.lastname: Fukai
authors.forename: T
authors.initials: T
authors.lastname: Okamura
authors.forename: H
authors.initials: H
authors.lastname: Asaba
authors.forename: T
authors.initials: T
authors.lastname: Sakai
mesh_terms: D001254:Astrocytoma / Q000150:complications / Q000175:diagnosis; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis; D002560:Cerebrovascular Circulation; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000175:diagnosis / Q000000981:diagnostic imaging*; D005625:Frontal Lobe / Q000000981:diagnostic imaging / Q000503:physiopathology; D007839:Functional Laterality; D006801:Humans; D018887:Landau-Kleffner Syndrome / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime