title: Activities of glycolipid glycosyltransferases and sialidases during the early development of Xenopus laevis.
abstract: The activities of glycosyltransferases and sialidases, together with the ganglioside content and distribution, have been extensively studied in mammals, while the informations on tissues of other animals, including amphibian, are scarce. In this paper we present data on the activities of SAT-1, SAT-2, SAT-4, SAT-5, GlcNAcT-1, GalNAcT-1, GalT-6, and sialidases studied in Xenopus laevis embryos at different stages of development. The highest activity was found at days 4 and 5 of embryogenesis for glycosyltransferases and sialidases respectively; a tentative correlation between the in vitro activity of these enzymes and the content of neutral and acidic glycolipids is discussed.
authors.affiliation: Institute of General Physiology and Biochemistry, University of Milan, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Gornati
authors.forename: S
authors.initials: S
authors.lastname: Basu
authors.forename: G
authors.initials: G
authors.lastname: Bernardini
authors.forename: A M
authors.initials: AM
authors.lastname: Rizzo
authors.forename: F
authors.initials: F
authors.lastname: Rossi
authors.forename: B
authors.initials: B
authors.lastname: Berra
mesh_terms: D000818:Animals; D005732:Gangliosides / Q000378:metabolism; D006017:Glycolipids / Q000378:metabolism*; D016695:Glycosyltransferases / Q000502:physiology*; D009439:Neuraminidase / Q000502:physiology*; D012799:Sialyltransferases / Q000502:physiology*; D014982:Xenopus laevis / Q000196:embryology* / Q000378:metabolism
chemical_list: D005732:Gangliosides; D006017:Glycolipids; D016695:Glycosyltransferases; D012799:Sialyltransferases; D009439:Neuraminidase