[The evaluation of the detoxication function of the kidneys by the clearance of middle molecules].
The detoxifying function of the kidneys was examined in 56 patients with renal diseases. The function was assessed from the clearance of medium-mass molecules in relation to the total water content in the body. Medium-mass molecules in the serum and urine were assessed by the method based on direct UV spectrophotometry. A correlation has been revealed between the content of medium-mass molecules, serum creatinine, clearance of creatinine, and the detoxifying function of the kidneys. The method is simple, reliable, and does not require expensive reagents.
Shutov
A M
AM
Prokaeva
P A
PA
Zhelezniakova
S V
SV
D000293:Adolescent; D000328:Adult; D000368:Aged; D001834:Body Water / Q000737:chemistry; D005260:Female; D006801:Humans; D007668:Kidney / Q000378:metabolism*; D007674:Kidney Diseases / Q000378:metabolism; D007677:Kidney Function Tests / Q000379:methods / Q000706:statistics & numerical data; D008297:Male; D008657:Metabolic Clearance Rate; D008875:Middle Aged; D008970:Molecular Weight; D010455:Peptides / Q000032:analysis / Q000378:metabolism*; D013056:Spectrophotometry, Ultraviolet
D010455:Peptides
Otsenka detoksikatsionnoĭ funktsii pochek po klirensu srednikh molekul.