Leiomyosarcoma of the pulmonary vein: case report with immunohistochemical and ultrastructural findings.
We report a case of neoplasia of pulmonary vein in a 45-year-old woman who presented with increasing dyspnea. As a consequence, the neoplasia filled the entire left atrium and appeared to be attached to the left superior pulmonary vein on surgical excision. Histologically, it was composed of a proliferation of sarcomatous cells, with a high mitotic rate and diffuse immunohistochemical positivity for smooth muscle actin, consistent with a leiomyosarcoma. The microscopic, immunohistochemical, and ultrastructural findings are discussed.
Leone
O
O
Institute of Pathology, University of Bologna, Italy.
Piana
S
S
Cenacchi
G
G
Farneti
P A
PA
Pilato
E
E
Pacini
D
D
Galli
R
R
Santini
D
D
Pileri
S
S
D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007890:Leiomyosarcoma / Q000737:chemistry* / Q000473:pathology / Q000648:ultrastructure*; D008875:Middle Aged; D011667:Pulmonary Veins / Q000737:chemistry* / Q000473:pathology / Q000648:ultrastructure*; D019043:Vascular Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure*