[Experimental studies on possible correction of MPEL of ethylenediamine in the workplace air].
The present MAC for ethylenediamine (2 mg/cu m) does not match up-to-date requirements of industrial medicine and requires experimental analysis. Using contemporary methodic approaches, the authors studied toxicodynamics of ethylenediamine, revealed parameters of its toxicity and jeopardy. Biologic effects of ethylenediamine are irritation, allergic signs and changes in central nervous system. Chronic inhalation experiment helped to determine the MAC for ethylenediamine at 0.3 mg/cu m, 2nd jeopardy grade, that requires labels "Allergen" and "Skin protection required".
Dubinina
O N
ON
Galeeva
L R
LR
Trubnikova
L I
LI
Varlamova
T I
TI
Tkacheva
S G
SG
D000485:Allergens; D000818:Animals; D002490:Central Nervous System / Q000187:drug effects; D005029:Ethylenediamines / Q000633:toxicity; D006168:Guinea Pigs; D007928:Lethal Dose 50; D008452:Maximum Allowable Concentration; D051379:Mice; D008962:Models, Theoretical; D011817:Rabbits; D051381:Rats; D012867:Skin / Q000187:drug effects
D000485:Allergens; D005029:Ethylenediamines; C031234:ethylenediamine
Eksperimental'nye issledovaniia k vozmozhnoĭ korrektirovke PDK étilendiamina v vozdukhe rabocheĭ zony.