title: Identifying changes in gene expression in the nervous system: mRNA differential display.
abstract: The majority of cellular and developmental processes are characterized by changes in gene expression. Recently, several polymerase chain reaction-based methods have been introduced for detecting genes whose expressions differ between cells or tissues. It is now possible to investigate whether novel gene expression occurs within many systems as a response to extracellular signals, and to identify systematically those genes. The characterization of cell-, tissue- or stage-specific gene expression will broaden our understanding of many complex biological processes.
authors.affiliation: MRC Laboratory of Molecular Biology, Cambridge, UK.
authors.forename: F J
authors.initials: FJ
authors.lastname: Livesey
authors.forename: S P
authors.initials: SP
authors.lastname: Hunt
mesh_terms: D000818:Animals; D015870:Gene Expression; D006801:Humans; D009420:Nervous System / Q000378:metabolism*; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000737:chemistry / Q000378:metabolism*
chemical_list: D012333:RNA, Messenger