Clinical and immunohistochemical analyses of parotid gland tumors.
Clinical, histological and immunohistochemical data on 71 parotid gland tumors were analyzed. Benign neoplasms accounted for 71.8% of the case material and malignant tumors 22.6%. Chronic parotitis occurred in 5.6% of the total case number. Pleomorphic adenomas and mucoepidermoid carcinomas were the most frequently occurring benign and malignant neoplasms. Pleomorphic adenomas stained positive for S-100 protein, tenascin, smooth muscle actin, synaptophysin and chromogranin A. This immunohistochemical, histological and clinical analysis was believed to be of potential assistance in the diagnosis, treatment and prognosis of parotid gland tumors.
Ozdziński
W
W
Department of Otorhinolaryngology, Medical University of Gdansk, Poland.
Kuczkowski
J
J
Debniak
E
E
Zołtowska
A
A
D000199:Actins / Q000032:analysis; D008949:Adenoma, Pleomorphic / Q000378:metabolism / Q000473:pathology; D000951:Antigens, Neoplasm / Q000032:analysis; D018277:Carcinoma, Mucoepidermoid / Q000378:metabolism / Q000473:pathology; D053379:Chromogranin A; D002864:Chromogranins / Q000032:analysis; D002908:Chronic Disease; D003893:Desmin / Q000032:analysis; D006023:Glycoproteins / Q000032:analysis; D006801:Humans; D007071:Immunoglobulin A, Secretory / Q000032:analysis; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D010307:Parotid Neoplasms / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D010309:Parotitis / Q000378:metabolism / Q000473:pathology; D011379:Prognosis; D009418:S100 Proteins / Q000032:analysis; D012635:Secretory Component / Q000032:analysis; D016708:Synaptophysin / Q000032:analysis; D019063:Tenascin / Q000032:analysis; D016159:Tumor Suppressor Protein p53 / Q000032:analysis
D000199:Actins; D000951:Antigens, Neoplasm; D053379:Chromogranin A; D002864:Chromogranins; D003893:Desmin; D006023:Glycoproteins; D007071:Immunoglobulin A, Secretory; D009418:S100 Proteins; D012635:Secretory Component; D016708:Synaptophysin; D019063:Tenascin; D016159:Tumor Suppressor Protein p53; C047052:tumor-associated antigen 72; D007633:Keratins