[The in-vivo test of the inhibition of leukocyte natural migration with aspirin and analgin in the specific diagnosis of the asthmatic triad].
Asthmatic triad (AT) is a clinical syndrome incorporating bronchial asthma (BA), recurrent nasal and sinus polyps, intolerance of aspirin, derivatives of pirasolone and other nonsteroid antiinflammatory drugs. Specific diagnosis of aspirin and analgin intolerance in patients with AT was made using the test of natural leukocyte emigration inhibition in vivo in the oral cavity. The test was performed in 22 patients with AT and 13 patients with BA with pollenosis without aspirin and analgin intolerance. In all the patients the test provided positive results, in control patients these were negative. High significance, safety and simplicity of the test made it applicable for specific diagnosis of AT in allergological and pulmonological departments.
Kanchurina
N A
NA
Poroshina
Iu A
IuA
Prasolova
N I
NI
Zemskov
V M
VM
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal; D001241:Aspirin; D001249:Asthma / Q000175:diagnosis*; D002464:Cell Migration Inhibition; D004177:Dipyrone; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D009298:Nasal Polyps / Q000175:diagnosis*; D012008:Recurrence; D012680:Sensitivity and Specificity; D013577:Syndrome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004177:Dipyrone; D001241:Aspirin
Test tormozheniia estestvennoĭ émigratsii leĭkotsitov in vivo s aspirinom i anal'ginom v spetsificheskoĭ diagnostike astmaticheskoĭ triady.