title: Syringomyelia developing as an acute complication of tuberculous meningitis.
abstract: BACKGROUND
  Tuberculosis of the nervous system has protean manifestations. Syringomyelia, though an uncommon complication of it, is usually of late onset.
  
  
  METHODS
  We report two patients with tuberculosis meningitis who developed syringomyelia acutely. The diagnosis was supported by neuroimaging and findings at laminectomy.
  
  
  RESULTS
  The two patients developed syringomyelia between 11 days and 6 weeks of the onset of tuberculous meningitis. They both had cord swelling and softening.
  
  
  CONCLUSIONS
  Acute-onset syringomyelia should be suspected in any patient being treated for tuberculosis meningitis who subsequently develops limb weakness and/or sphincteric dysfunction. Inflammatory edema and cord ischemia appeared to be the underlying mechanisms in these early onset cases rather than arachnoiditis which is important in late-onset cases.
authors.affiliation: Division of Neurology and Radiology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
authors.forename: A K
authors.initials: AK
authors.lastname: Daif
authors.forename: S
authors.initials: S
authors.lastname: al Rajeh
authors.forename: A
authors.initials: A
authors.lastname: Ogunniyi
authors.forename: A
authors.initials: A
authors.lastname: al Boukai
authors.forename: A
authors.initials: A
authors.lastname: al Tahan
mesh_terms: D000208:Acute Disease; D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008297:Male; D013116:Spinal Cord / Q000000981:diagnostic imaging; D013595:Syringomyelia / Q000000981:diagnostic imaging / Q000209:etiology*; D014057:Tomography, X-Ray Computed; D014390:Tuberculosis, Meningeal / Q000150:complications* / Q000000981:diagnostic imaging