title: Vessel tearing at the edge of intracoronary stents detected with intravascular ultrasound imaging.
abstract: Stent deployment strategies have changed significantly in the past 2 yr, with "high-pressure" balloon inflations postdilatation being performed in the large majority of cases. There is currently little information about the effects of high pressure on the geometry of stent expansion and on the adjacent areas of the vessel wall. Intravascular ultrasound (IVUS) imaging is well-suited to investigate these issues, since it provides information not only about stent expansion and apposition but also about adjacent vessel-wall morphology at transition points such as the articulation site of the stent and the the stent borders. We report on the results of a cohort of 30 consecutive stent cases which were systematically examined by IVUS following high-pressure inflation. All deployments were deemed successful by angiographic inspection. However, in 6 cases, intimal disruptions or "edge tears" were noted at the stent borders by IVUS. In 5 cases, edge tears were seen to occur at the distal border, whereas in one case edge tears were seen at both the proximal and distal edges of the stent. No angiographic and sonographic parameters were different except percent plaque area at the stent margins, which was significantly higher (53 +/- 11%) in the lesions with edge tears, compared to 40 +/- 10% plaque area in the group without evidence of pocket flaps (P = 0.007). This experience suggests that intimal disruptions or "edge tears" are a relatively common occurrence following high-pressure stent deployment, and may be related to the extent of marginal dissections.
authors.affiliation: Center for Research in Cardiovascular Interventions, Stanford University, California 94305, USA.
authors.forename: S P
authors.initials: SP
authors.lastname: Schwarzacher
authors.forename: J A
authors.initials: JA
authors.lastname: Metz
authors.forename: P G
authors.initials: PG
authors.lastname: Yock
authors.forename: P J
authors.initials: PJ
authors.lastname: Fitzgerald
mesh_terms: D000800:Angioplasty, Balloon / Q000379:methods*; D003327:Coronary Disease / Q000601:surgery; D003331:Coronary Vessels / Q000000981:diagnostic imaging* / Q000293:injuries*; D006801:Humans; D011312:Pressure; D015607:Stents / Q000009:adverse effects*; D018084:Ultrasonography, Interventional