title: SPECT with In-111 autologous platelets to detect residual splenic tissue in two patients with relapsed thrombocytopenia.
abstract: In two patients with relapsed thrombocytopenia, the authors used SPECT with In-111 labeled autologous platelets to identify residual splenic tissue after splenectomy. One case involved a previously splenectomized patient with idiopathic portal hypertension, while the other had relapsed chronic idiopathic thrombocytopenic purpura (ITP). In both patients, SPECT showed a higher In-111 uptake in the splenic tissues compared with planar images. In the patient with ITP, a small accessory spleen had been overlooked on abdominal CT because of post-operative changes, but it was identified by superimposition of SPECT/CT images. These cases indicate that In-111 platelet SPECT is useful in detecting and localizing residual accessory splenic tissue associated with relapsed thrombocytopenia.
authors.affiliation: Department of Radiology, Yamaguchi University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Suga
authors.forename: K
authors.initials: K
authors.lastname: Nishigauchi
authors.forename: K
authors.initials: K
authors.lastname: Shimizu
authors.forename: N
authors.initials: N
authors.lastname: Kume
authors.forename: N
authors.initials: N
authors.lastname: Matsunaga
authors.forename: Y
authors.initials: Y
authors.lastname: Sato
authors.forename: A
authors.initials: A
authors.lastname: Tangoku
authors.forename: N
authors.initials: N
authors.lastname: Kouichi
authors.forename: K
authors.initials: K
authors.lastname: Esato
mesh_terms: D000328:Adult; D000368:Aged; D001792:Blood Platelets; D006801:Humans; D007205:Indium Radioisotopes; D008297:Male; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000000981:diagnostic imaging / Q000601:surgery; D012008:Recurrence; D013154:Spleen / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D013156:Splenectomy; D013921:Thrombocytopenia / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: D007205:Indium Radioisotopes