title: MLL cleavage occurs in approximately 5% of de novo acute myeloid leukemia, including in patients analyzed before treatment induction.
authors.forename: E
authors.initials: E
authors.lastname: Macintyre
authors.forename: P
authors.initials: P
authors.lastname: Bourquelot
authors.forename: D
authors.initials: D
authors.lastname: Leboeuf
authors.forename: R
authors.initials: R
authors.lastname: Rimokh
authors.forename: E
authors.initials: E
authors.lastname: Archimbaud
authors.forename: T
authors.initials: T
authors.lastname: Smetsers
authors.forename: R
authors.initials: R
authors.lastname: Zittoun
mesh_terms: D000208:Acute Disease; D002880:Chromosomes, Human, Pair 11; D053938:DNA Fragmentation; D004268:DNA-Binding Proteins / Q000235:genetics*; D011495:Histone-Lysine N-Methyltransferase; D006801:Humans; D007951:Leukemia, Myeloid / Q000188:drug therapy* / Q000235:genetics*; D051788:Myeloid-Lymphoid Leukemia Protein; D011519:Proto-Oncogenes; D012074:Remission Induction; D014157:Transcription Factors
chemical_list: D004268:DNA-Binding Proteins; C497422:KMT2A protein, human; D014157:Transcription Factors; D051788:Myeloid-Lymphoid Leukemia Protein; D011495:Histone-Lysine N-Methyltransferase