title: Synthesis, characterisation and antifungal activity of some N-bridged heterocycles derived from 3-(3-bromo-4-methoxyphenyl)-4-amino-5-mercapto-1,2,4-triazole.
abstract: 3-(3-Bromo-4-methoxyphenyl)-4-amino-5-mercapto-1,2,4-triazole was prepared starting from p-anisic acid. This new triazole was employed in the synthesis of some N-bridged heterocycles. All the newly synthesized compounds were characterized by analytical, IR, 1H-NMR and Mass Spectral studies. Some of the newly synthesized compounds were screened for their antifungal property against Thielaviopsis paradoxa, a fungus which is reported to cause stem-bleeding disease in coconut plants.
authors.affiliation: Department of P.G. Studies & Research in Chemistry, Mangalore University, India.
authors.forename: B S
authors.initials: BS
authors.lastname: Holla
authors.forename: K N
authors.initials: KN
authors.lastname: Poojary
authors.forename: B
authors.initials: B
authors.lastname: Kalluraya
authors.forename: P V
authors.initials: PV
authors.lastname: Gowda
mesh_terms: D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi / Q000187:drug effects*; D013055:Spectrophotometry, Infrared; D013830:Thiadiazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D014230:Triazoles / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000935:Antifungal Agents; D013830:Thiadiazoles; D014230:Triazoles