title: Clinicopathological findings in human autopsy eyes with an Anis circular lens.
abstract: OBJECTIVE
  To evaluate the long-term performance of the Anis circular intraocular lens (IOL).
  
  
  METHODS
  Center for IOL Research, Storm Eye Institute, Charleston, South Carolina.
  
  
  METHODS
  Fifteen human autopsy eyes with an Anis circular IOL submitted between 1985 and 1993 were evaluated. The eyes were sectioned at the equatorial plane, and the anterior segment containing the capsular bag and the IOL was photographed from the posterior perspective. Fixation, centration, capsular bag shape, zonular damage, central posterior capsule opacification (PCO), and Soemmering's ring formation were analyzed. The results were compared with those of a control group comprising human autopsy eyes with a one-piece (n = 15) or three-piece (n = 15) poly(methyl methacrylate) IOL with a C-loop design.
  
  
  RESULTS
  All 15 Anis IOLs showed symmetrical in-the-bag fixation. Mean decentration in the Anis IOL eyes was significantly lower than in the control eyes (P = .02). Eyes with the Anis IOL had fewer zonular defects (P = .0005) and a better circular extension of the capsular bag (P = .003). There were no statistically significant differences in PCO (P = .29) or Soemmering's ring formation (P = .67).
  
  
  CONCLUSIONS
  The Anis IOL with a circular haptic design had better centration and capsular bag morphology than the control eyes, although a difference in PCO and Soemmering's ring formation could not be shown.
authors.affiliation: Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston 29425-2236, USA.
authors.forename: G U
authors.initials: GU
authors.lastname: Auffarth
authors.forename: C
authors.initials: C
authors.lastname: McCabe
authors.forename: M R
authors.initials: MR
authors.lastname: Tetz
authors.forename: D J
authors.initials: DJ
authors.lastname: Apple
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000869:Anterior Eye Segment / Q000473:pathology* / Q000601:surgery; D002102:Cadaver; D006801:Humans; D007903:Lens Capsule, Crystalline / Q000473:pathology* / Q000601:surgery; D007910:Lenses, Intraocular; D008768:Methylmethacrylates; D011183:Postoperative Complications / Q000473:pathology; D011474:Prosthesis Design; D011680:Pupil; D012189:Retrospective Studies
chemical_list: D008768:Methylmethacrylates