title: A prospective comparison of octylcyanoacrylate tissue adhesive and suture for the closure of head and neck incisions.
abstract: OBJECTIVE
  To compare the tissue adhesive octylcyanoacrylate with subcuticular suture for the closure of head and neck incisions.
  
  
  METHODS
  A prospective comparison with a blinded assessment of cosmetic outcome.
  
  
  METHODS
  Fifty consecutive patients undergoing head and neck procedures at two University of Ottawa teaching hospitals.
  
  
  METHODS
  Twenty-six patients underwent skin closure with monofilament suture and 24 were closed with tissue adhesive. At 4 to 6 weeks the incisions were evaluated with a validated wound scale. Photographs of the incisions were rated using a visual analogue scale by two facial-plastic otolaryngologists who were blinded to the method of skin closure.
  
  
  RESULTS
  The adhesive provided faster skin closure (29.7 seconds vs 289.0 seconds, p < .0001), and there were no differences in complications between the two groups. The primary outcome measure was the cosmetic appearance of the incision at 4 to 6 weeks. Although the adhesive group scored higher on both cosmesis scales, the visual analogue scale (octylcyanoacrylate 58.7 mm vs suture 53.2 mm) and the wound evaluation scale (57% vs 50% optimal wound scores), there were no statistical or clinically significant differences on either scale. The two facial-plastic otolaryngologists had good intraobserver and interobserver agreement when rating the cosmetic outcomes (0.87 and 0.71 respectively).
  
  
  CONCLUSIONS
  Octylcyanoacrylate was found to be an effective method of skin closure in clean head and neck incisions. The practical advantages of tissue adhesives are reviewed.
authors.affiliation: Department of Otolaryngology, University of Ottawa Faculty of Medicine, Ontario.
authors.forename: J L
authors.initials: JL
authors.lastname: Maw
authors.forename: J V
authors.initials: JV
authors.lastname: Quinn
authors.forename: G A
authors.initials: GA
authors.lastname: Wells
authors.forename: Y
authors.initials: Y
authors.lastname: Ducic
authors.forename: P F
authors.initials: PF
authors.lastname: Odell
authors.forename: A
authors.initials: A
authors.lastname: Lamothe
authors.forename: P J
authors.initials: PJ
authors.lastname: Brownrigg
authors.forename: T
authors.initials: T
authors.lastname: Sutcliffe
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013537:Sutures; D014014:Tissue Adhesives; D014945:Wound Healing
chemical_list: D014014:Tissue Adhesives