Intranasal midazolam in patients with status epilepticus.
The patient in status epilepticus presents many challenges to the emergency physician. IV access is frequently difficult to achieve, and prolonged attempts at access can jeopardize the patient and endanger the caregiver. We present two cases in which the administration of intranasal midazolam appeared to successfully terminate status epilepticus. No adverse effects were noted. Studies are needed to clarify the safety, optimal dosing, and clinical utility of this treatment modality.
Kendall
J L
JL
Department of Emergency Medicine, Los Angeles County-University of Southern California Medical Center, USA.
Reynolds
M
M
Goldberg
R
R
D000281:Administration, Intranasal; D000927:Anticonvulsants / Q000008:administration & dosage*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage*; D008297:Male; D008874:Midazolam / Q000008:administration & dosage*; D008875:Middle Aged; D013226:Status Epilepticus / Q000188:drug therapy*
D000927:Anticonvulsants; D006993:Hypnotics and Sedatives; D008874:Midazolam