[Changes in the renin-angiotensin-aldosterone system and water-salt exchange in mining workers in coal mines].
Blood and urine content of electrolytes and creatinine was determined in 76 essentially healthy miners before and after work shift, as was activity of plasma renin, blood plasma level of aldosterone and its urinary excretion, with the aid of radioimmunoassay. The greatest activity of the renin-angiotensine-aldosterone system (RAAS) occurred in those individuals engaged in hard physical labour under most harsh conditions of underground workings, this being recordable not only is response to the load but also from the very start. Controls and miners doing jobs of medium-level strenuousness demonstrated changes in the correlations between RAAS and water-salt balance after the work shift as compared with those before the work shift, while in those miners engaged in hard work correlations RAAS-water-salt exchange remained practically the same throughout the study.
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B A
BA
D003032:Coal Mining; D005919:Glomerular Filtration Rate; D006801:Humans; D016273:Occupational Exposure; D012016:Reference Values; D012084:Renin-Angiotensin System; D014455:Ukraine; D014882:Water-Electrolyte Balance; D014937:Work / Q000502:physiology
Izmeneniia renin-angiotenzin-al'dosteronovoĭ sistemy i vodno-solevogo obmena u gornorabochikh ugol'nykh shakht.