title: Duodenogastric reflux after choledochoduodenostomy.
abstract: Duodenogastric reflux (DGR) has been implicated in several disease processes. The present study was carried out to document the incidence and evaluate the clinical significance of DGR after choledochoduodenostomy (CDD). A total of 13 patients who had undergone cholecystectomy with a standard side-to-side CDD for choledocholithiasis or chronic pancreatitis were studied by symptom evaluation, scintigraphy, endoscopy, and gastric mucosal histology at least 6 months after surgery. The scintigraphic findings were then compared with those of 10 patients who had undergone cholecystectomy alone. Only two patients (15%) had mild dyspeptic symptoms. The incidence of DGR after CDD was 69% compared to 20% in the cholecystectomy alone group (P < 0.05). In the majority of patients the DGR was only mild to moderate and the severity correlated well with the degree of endoscopic gastritis, but not with the clinical symptoms or histological findings. These results indicate that while CDD is associated with a high incidence of DGR, its occurrence does not produce significant clinical symptoms.
authors.affiliation: Department of Surgical Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Rae Bareli, Lucknow, India.
authors.forename: W
authors.initials: W
authors.lastname: Ali
authors.forename: D K
authors.initials: DK
authors.lastname: Agarwal
authors.forename: S S
authors.initials: SS
authors.lastname: Sikora
authors.forename: B R
authors.initials: BR
authors.lastname: Mittal
authors.forename: N
authors.initials: N
authors.lastname: Krishnani
authors.forename: M
authors.initials: M
authors.lastname: Ibrarullah
authors.forename: R K
authors.initials: RK
authors.lastname: Gupta
authors.forename: S P
authors.initials: SP
authors.lastname: Kaushik
mesh_terms: D000328:Adult; D002768:Choledochostomy / Q000009:adverse effects*; D002908:Chronic Disease; D004383:Duodenogastric Reflux / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D016099:Endoscopy, Gastrointestinal; D005260:Female; D042882:Gallstones / Q000601:surgery; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000601:surgery; D011877:Radionuclide Imaging