title: Ciprofloxacin treatment of bacterial endocarditis involving prosthetic material after cardiac surgery.
abstract: Two children with cyanotic congenital heart disease and Gram negative bacterial infection of prosthetic material after cardiac surgery were treated successfully with oral ciprofloxacin, initially in combination with netilmicin. The use of oral ciprofloxacin allowed prolonged outpatient treatment to be given, avoiding the need for intravenous access and early repeat surgery.
authors.affiliation: Department of Medical Microbiology, Bristol Royal Infirmary.
authors.forename: N M
authors.initials: NM
authors.lastname: Brown
authors.forename: R J
authors.initials: RJ
authors.lastname: Körner
authors.forename: C E
authors.initials: CE
authors.lastname: Zollman
authors.forename: R P
authors.initials: RP
authors.lastname: Martin
authors.forename: M R
authors.initials: MR
authors.lastname: Millar
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001807:Blood Vessel Prosthesis; D002648:Child; D002675:Child, Preschool; D002939:Ciprofloxacin / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004697:Endocarditis, Bacterial / Q000188:drug therapy*; D005839:Gentamicins / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009428:Netilmicin / Q000627:therapeutic use*; D016459:Prosthesis-Related Infections / Q000188:drug therapy*
chemical_list: D000890:Anti-Infective Agents; D005839:Gentamicins; D009428:Netilmicin; D002939:Ciprofloxacin