title: Binding of Cu2+, Zn2+, and Ni(2+)-GnRH complexes with the rat pituitary receptor.
abstract: Complex of copper with the gonadotropin-releasing hormone, GnRH, competed more efficiently for the GnRH receptor than native GVRH, while complexes of nickel with GnRH and zinc with GnRH had slightly lower affinity. Copper ion added to the incubation mixture inhibited the buserelin binding to the receptor.
authors.affiliation: Institute of Animal Physiology and Nutrition, Jabłonna, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Kochman
authors.forename: A
authors.initials: A
authors.lastname: Gajewska
authors.forename: H
authors.initials: H
authors.lastname: Kochman
authors.forename: H
authors.initials: H
authors.lastname: Kozłowski
authors.forename: E
authors.initials: E
authors.lastname: Masiukiewicz
authors.forename: B
authors.initials: B
authors.lastname: Rzeszotarska
mesh_terms: D000818:Animals; D001667:Binding, Competitive; D002064:Buserelin / Q000378:metabolism; D003300:Copper / Q000378:metabolism*; D007987:Gonadotropin-Releasing Hormone / Q000378:metabolism*; D007700:Kinetics; D009532:Nickel / Q000378:metabolism*; D010903:Pituitary Gland, Anterior / Q000378:metabolism*; D051381:Rats; D011966:Receptors, LHRH / Q000378:metabolism*; D015032:Zinc / Q000378:metabolism*
chemical_list: D011966:Receptors, LHRH; D007987:Gonadotropin-Releasing Hormone; D003300:Copper; D009532:Nickel; D015032:Zinc; D002064:Buserelin