Formation of neoureter from peritoneum in live animal model (dog).
Regeneration of ureter in vivo is possible from peritoneal stem cells as both are derivative of embryonal germ layer mesoderm. The peritoneal stem cells are engaged in repair of loss due to normal wear and tear by differentiation and proliferation. With pluripotent nature, they have a capacity to undergo metaplastic transformation to various mesodermal tissues. The intrinsic cell factor along with regional tissue organisers coupled with functional need of the region, a desired metaplastic transformation to ureteric wall components is possible.
Matapurkar
B G
BG
Department of Surgery, Maulana Azad Medical College & Associated Lok Nayak Hospital, New Delhi, India.
Rehan
H M
HM
D000818:Animals; D004285:Dogs; D005260:Female; D008297:Male; D008679:Metaplasia; D008954:Models, Biological; D010537:Peritoneum / Q000166:cytology / Q000502:physiology* / Q000637:transplantation; D012038:Regeneration / Q000502:physiology*; D013234:Stem Cells / Q000502:physiology; D014182:Transplantation, Autologous; D014513:Ureter / Q000502:physiology*