title: MR imaging of acoustic neuroma with high resolution fast spin echo T2-weighted sequence.
abstract: OBJECTIVE
  To assess the value of high resolution 2D fast spin echo T2-weighted sequence (HR 2D-FSE T2w) for evaluating the internal auditory meatus (IAM) in patients with asymetric or unilateral sensorineural hearing loss, vs. gadolinium-enhanced T1-weighted (T1w) sequence; to suggest a screening protocol to exclude the diagnosis of acoustic neuroma in a patient with isolated unilateral sensorineural hearing loss.
  
  
  METHODS
  One-hundred ten patients with suspected acoustic neuroma were evaluated with 1.5 T MRI system. The protocol included axial images focused on the IAM: HR 2D-FSE T2w images (4000/63, ETL = 16, 3-mm sections with 1.5 mm overlap, 18 FOV, 512 x 384 matrix) and gadolinium-enhanced T1w images (600/23, 3-mm sections, 18 FOV, 256 x 192 matrix). Two criteria for normality of the HR 2D-FSE T2w examination are defined: high homogeneous signal of the cerebellospinal fluid (CSF) and linear low signal of the nerves visible throughout the IAM.
  
  
  RESULTS
  Overall results show no false-negative and six false-positive with HR 2D-FSE T2w sequences vs. gadolinium-enhanced T1w sequences. The sensitivity of HR 2D-FSE T2w sequences is 100%, specificity 93%, and negative preditive value 100%: normal images using HR 2D-FSE T2w sequence can rule out the diagnosis of acoustic neuroma.
  
  
  CONCLUSIONS
  Using this protocol we can exclude the diagnosis of acoustic neuroma in case of normal HR 2D-FSE images and no additional gadolinium-enhanced T1w sequence is necessary. This protocol might reduce examination time, must promote recourse to MRI in the event of clinical suspicion of acoustic neuroma, and also enables savings by proposing MRI examination as a first-line exam.
authors.affiliation: Department of Radiology, Armed Forces Hospital of Val-de-Grâce, Paris, France. cerval@planete.net
authors.forename: D
authors.initials: D
authors.lastname: Soulié
authors.forename: Y S
authors.initials: YS
authors.lastname: Cordoliani
authors.forename: J
authors.initials: J
authors.lastname: Vignaud
authors.forename: G
authors.initials: G
authors.lastname: Cosnard
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002530:Cerebellopontine Angle / Q000033:anatomy & histology*; D003937:Diagnosis, Differential; D005260:Female; D005682:Gadolinium; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000150:complications / Q000175:diagnosis*; D011446:Prospective Studies; D000159:Vestibulocochlear Nerve / Q000033:anatomy & histology*
chemical_list: D005682:Gadolinium