title: Trends in clinical outcome of transitional cell carcinoma of the ureter: have the results improved?
abstract: We divided 53 consecutive patients with transitional cell carcinoma of the ureter into two groups. Group A consisted of patients treated in the 1970s and group B of patients treated in the 1980s. Clinical features and outcomes were compared between the groups. Group B patients saw an increased use of new diagnostic modalities, including antegrade pyelography, computed tomography, and bone scintigraphy. Regional lymphadenectomy was added to the operative routine in group B and combined chemotherapy, using methotrexate, vinblastine, adriamycin and cisplatinum, the most effective regimen at present, was used in 9 patients in group B and no patients in group A. In spite of new diagnostic modalities and treatments, the survival rate for ureteral cancer failed to improve from the 1970s to the 1980s.
authors.affiliation: Department of Urology, School of Medicine, Kanazawa University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kunimi
authors.forename: T
authors.initials: T
authors.lastname: Amano
authors.forename: T
authors.initials: T
authors.lastname: Uchibayashi
authors.forename: M
authors.initials: M
authors.lastname: Ohkawa
authors.forename: M
authors.initials: M
authors.lastname: Namiki
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D016022:Case-Control Studies; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016019:Survival Analysis; D015996:Survival Rate / Q000639:trends; D016896:Treatment Outcome; D014516:Ureteral Neoplasms / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy