HIV-2 prevalence in Uttar Pradesh.
Serum samples collected since 1989 with various patterns of reactivity for human immunodeficiency virus (HIV)-1, on the basis of screening ELISA and confirmatory Western blot (WB) test, were subjected to the detection of HIV-2 infection based on screening dot immunoassay and confirmatory WB for HIV-2. Significant prevalence of HIV-2 infection was (37.03%) among sera reactive for HIV-1 by ELISA but indeterminate by Western blot, compared with sera reactive for HIV-1 by ELISA and WB (3.29%) or negative by WB (2.63%). Out of 16 HIV-2 positive sera, 5 (31.25%) showed evidence of concomitant HIV-1 infection. This study demonstrates evidence of HIV-2 infection as early as 1989, earlier than reported so far from India.
Kulshreshtha
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R
Postgraduate Department of Microbiology, K.G. Medical College, Lucknow.
Mathur
A
A
Chattopadhya
D
D
Chaturvedi
U C
UC
D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology*; D000293:Adolescent; D000328:Adult; D015497:HIV-1; D006801:Humans; D007194:India / Q000453:epidemiology; D008875:Middle Aged; D015995:Prevalence; D013997:Time Factors