title: [Optimization of the diagnosis and treatment of anemias under exposure to aromatic-type organic solvents].
abstract: 171 iron-deficient painters and 20 subjects with chronic intoxication with aromatic hydrocarbons were studied in a large aircraft construction factory. After correlative analysis of iron metabolism, ferritin, erythrocytes, diameter and perimeter of reticulocytes, length of service three types of iron-deficiency were identified: typical, with evident toxicity, with a high risk of toxic damage. An important role of lipid peroxidation activity and toxic erythrocyto-membranopathy for pathomorphosis of iron deficiency anemia and progress of toxic anemia is demonstrated. A differential approach to treatment of different anemia variants was used. The treatment included membranoprotectors (alpha-tocopherol, essential, lypostabil) and unspecific detoxication (SUMS-enterosorbent, unitiol).
authors.forename: L A
authors.initials: LA
authors.lastname: Shpagina
authors.forename: M I
authors.initials: MI
authors.lastname: Loseva
authors.forename: T M
authors.initials: TM
authors.lastname: Sukharevskaia
authors.forename: V I
authors.initials: VI
authors.lastname: Sharapov
authors.forename: O V
authors.initials: OV
authors.lastname: Sazonova
authors.forename: S V
authors.initials: SV
authors.lastname: Tret'iakov
mesh_terms: D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D000401:Aircraft; D000740:Anemia / Q000097:blood / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D018798:Anemia, Iron-Deficiency / Q000097:blood / Q000139:chemically induced / Q000175:diagnosis / Q000628:therapy; D002908:Chronic Disease; D003131:Combined Modality Therapy; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects; D008297:Male; D009784:Occupational Diseases / Q000097:blood / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D010150:Paint / Q000009:adverse effects; D012997:Solvents / Q000009:adverse effects*
chemical_list: D000395:Air Pollutants, Occupational; D012997:Solvents
vernacular_title: Optimizatsiia diagnostiki i lecheniia anemiĭ v usloviiakh vozdeĭstviia organicheskikh rastvoriteleĭ aromaticheskogo riada.