Hypothermia-induced changes of afferent sensory transmission to the SI cortex of rats and hamsters.
The effects of acute lowering of body temperature on afferent sensory transmission to the primary somatosensory cortex were determined quantitatively in anaesthetized rats and hamsters. Rats showed no change in afferent sensory transmission until 27 degrees C, but dramatic suppression between 26 degrees C and 22 degrees C, reaching 100% inhibition at 21 degrees C. Hamsters exhibited gradual suppression of sensory transmission from 34 degrees C to 18 degrees C, reaching 95% inhibition at 18 degrees C. Differential effects were also observed during rewarming up to 37 degrees C. Response latencies were also differentially affected during hypothermia in rats and hamsters. These results suggest the presence of inherently different neural mechanisms to process somatosensory information during transient lowering of body temperature between hibernators and non-hibernators.
Won
C K
CK
Department of Physiology, College of Medicine, Hallym University, Kangwondo, Korea.
Kim
B
B
Jung
N P
NP
Oh
Y K
YK
Choi
I H
IH
Park
H W
HW
Shin
H C
HC
D000818:Animals; D006224:Cricetinae; D005071:Evoked Potentials / Q000502:physiology; D006605:Hibernation / Q000502:physiology*; D007035:Hypothermia / Q000503:physiopathology*; D008647:Mesocricetus; D009475:Neurons, Afferent / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013003:Somatosensory Cortex / Q000166:cytology / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology*; D014738:Vibrissae / Q000502:physiology