title: High-performance liquid chromatographic analysis of cyclosporin A and its oral solutions.
abstract: Different columns and conditions were evaluated for the HPLC analysis of cyclosporin A, its congeners and degradation products. The optimised conditions were compared with the pharmacopoeial HPLC method for cyclosporin A analysis and some modifications, applicable among others for the stability studies of oral dosage forms, are proposed.
authors.affiliation: Galena Co., Department of Analytical Chemistry, Opava-Komárov, Czech Republic.
authors.forename: A
authors.initials: A
authors.lastname: Husek
mesh_terms: D000595:Amino Acid Sequence; D002851:Chromatography, High Pressure Liquid; D016572:Cyclosporine / Q000032:analysis*; D007202:Indicators and Reagents; D008969:Molecular Sequence Data; D012996:Solutions
chemical_list: D007202:Indicators and Reagents; D012996:Solutions; D016572:Cyclosporine