title: Conjugative transfer of high-level mupirocin resistance from Staphylococcus haemolyticus to other staphylococci.
abstract: A conjugative plasmid, pXU10, encoding high-level mupirocin resistance was transferred from a Staphylococcus haemolyticus isolate, CN216, to other coagulase-negative staphylococci and a restriction deficient Staphylococcus aureus strain, XU21, but not to clinical isolates or a restriction-proficient laboratory strain (strain WBG541) of S. aureus. However, from XU21 it was cotransferred with a 3.5-kb chloramphenicol resistance plasmid to WBG541. The results demonstrated the ability of pXU10 to mobilize nonconjugative plasmids.
authors.affiliation: Department of Microbiology, Faculty of Medicine, Kuwait University, Kuwait. Edet@hsccmail.kuniv.edu.kw
authors.forename: E E
authors.initials: EE
authors.lastname: Udo
authors.forename: L E
authors.initials: LE
authors.lastname: Jacob
authors.forename: E M
authors.initials: EM
authors.lastname: Mokadas
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003227:Conjugation, Genetic; D004352:Drug Resistance, Microbial / Q000235:genetics; D018014:Gene Transfer Techniques; D016712:Mupirocin / Q000494:pharmacology*; D010957:Plasmids / Q000235:genetics; D015183:Restriction Mapping; D013210:Staphylococcus / Q000187:drug effects* / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; D016712:Mupirocin