title: Free synovium promotes meniscal healing. Synovium, muscle and synthetic mesh compared in dogs.
abstract: We studied the effect of free synovium on the healing of tears in the avascular portion of the menisci in dogs. A longitudinal incision was made in the medial meniscus. In 35 dogs, a free graft of synovium was inserted into the tear and sutured. In 10 dogs, a free graft of quadriceps muscle was used. In 10 dogs, a Dacron mesh was inserted. In the contralateral knee, the tear was sutured without implantation as a control. 2, 4, 6, 8, and 12 weeks after the operation, the menisci were dissected. 11 of the 35 with free synovium were healed. The menisci with muscle grafts, those with Dacron mesh and those in the control group did not heal. Histology showed that tears were repaired with fibrous tissue. Microangiography showed that capillaries grew from the periphery, but they did not reach the tear.
authors.affiliation: Department of Orthopaedic Surgery, Gunma University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Shirakura
authors.forename: M
authors.initials: M
authors.lastname: Niijima
authors.forename: Y
authors.initials: Y
authors.lastname: Kobuna
authors.forename: S
authors.initials: S
authors.lastname: Kizuki
mesh_terms: D000818:Animals; D004285:Dogs; D008592:Menisci, Tibial / Q000502:physiology* / Q000601:surgery; D018482:Muscle, Skeletal / Q000637:transplantation*; D011093:Polyethylene Terephthalates; D013526:Surgical Mesh; D013583:Synovial Membrane / Q000637:transplantation*; D000070600:Tibial Meniscus Injuries; D014945:Wound Healing
chemical_list: D011093:Polyethylene Terephthalates