[Free radical centers in isolated rat myocardium during perfusion with the normally oxygenated substrate-free solution].
EPR spectroscopy was used to measure free radical species of samples of working rat hearts freeze-clamped during their perfusion under normal conditions as well as using the substrate-free solution. It has been obtained that the transition to the substrate-free state results in decreasing of concentration of flavosemiquinones in the tissue which causes: the changes in spectral and relaxational characteristics of EPR spectra of the samples and 1,3-fold decrease of the content of free radical centers in myocardium.
Timoshin
A A
AA
Lakomkin
V L
VL
Ruuge
E K
EK
D000818:Animals; D004578:Electron Spin Resonance Spectroscopy; D005182:Flavin-Adenine Dinucleotide / Q000031:analogs & derivatives / Q000737:chemistry; D005609:Free Radicals; D005615:Freezing; D008297:Male; D015425:Myocardial Reperfusion; D009206:Myocardium / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar
D005609:Free Radicals; D005182:Flavin-Adenine Dinucleotide; C029276:flavin semiquinone
Svobodnoradikal'nye tsentry v tkani izolirovannogo miokarda krysy v usloviiakh perfuzii bessubstratbym rastvorom s normal'noĭ oksigenatsieĭ.