Moyamoya disease in Brazil.
BACKGROUND
Moyamoya disease was first believed to be confined to Japan, but over the years it has been reported all over the world. We report seven cases from the University Hospital of the Faculty of Medicine of Ribeirão Preto, University of São Paulo with a review of the previously described cases in Brazil.


METHODS
The diagnosis was based on the diagnostic criteria of the Research Committee on Spontaneous Occlusion of the Circle of Willis.


RESULTS
Five patients presented ischemic and two hemorrhagic events. The meta-analysis of the six cases previously described in Brazil showed that only two were true moyamoya disease according to the diagnostic criteria.


CONCLUSIONS
We can assume that the real frequency of moyamoya disease has been underestimated in Brazil.
Minelli
C
C
Department of Neurology, Faculty of Medicine of Ribeiräo Preto, University of São Paulo, Brazil.
Takayanagui
O M
OM
dos Santos
A C
AC
Fabio
S C
SC
Lima
J E
JE
Sato
T
T
Colli
B O
BO
D000293:Adolescent; D000328:Adult; D001938:Brazil / Q000453:epidemiology; D002533:Cerebral Angiography; D002648:Child; D002941:Circle of Willis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009072:Moyamoya Disease / Q000175:diagnosis / Q000453:epidemiology*; D011446:Prospective Studies