title: [Free radical centers in isolated rat myocardium during perfusion with the normally oxygenated substrate-free solution].
abstract: EPR spectroscopy was used to measure free radical species of samples of working rat hearts freeze-clamped during their perfusion under normal conditions as well as using the substrate-free solution. It has been obtained that the transition to the substrate-free state results in decreasing of concentration of flavosemiquinones in the tissue which causes: the changes in spectral and relaxational characteristics of EPR spectra of the samples and 1,3-fold decrease of the content of free radical centers in myocardium.
authors.forename: A A
authors.initials: AA
authors.lastname: Timoshin
authors.forename: V L
authors.initials: VL
authors.lastname: Lakomkin
authors.forename: E K
authors.initials: EK
authors.lastname: Ruuge
mesh_terms: D000818:Animals; D004578:Electron Spin Resonance Spectroscopy; D005182:Flavin-Adenine Dinucleotide / Q000031:analogs & derivatives / Q000737:chemistry; D005609:Free Radicals; D005615:Freezing; D008297:Male; D015425:Myocardial Reperfusion; D009206:Myocardium / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D005609:Free Radicals; D005182:Flavin-Adenine Dinucleotide; C029276:flavin semiquinone
vernacular_title: Svobodnoradikal'nye tsentry v tkani izolirovannogo miokarda krysy v usloviiakh perfuzii bessubstratbym rastvorom s normal'noĭ oksigenatsieĭ.