title: The history of the psychopharmacology of schizophrenia.
abstract: OBJECTIVE
  To review the historical development of the psychopharmacological treatment of schizophrenia.
  
  
  METHODS
  A chronological literature review of the clinical practices and theoretical models that have controlled drug treatment of schizophrenia at different times.
  
  
  RESULTS
  Effective treatment of schizophrenia was achieved only after the introduction of antipsychotic drugs, in the 1950s, and is still progressing.
  
  
  CONCLUSIONS
  Close collaboration between basic neuroscience and careful and informed clinical practice are likely to lead to continued progress.
authors.affiliation: Department of Psychiatry, McGill University, Montreal, Quebec.
authors.forename: H E
authors.initials: HE
authors.lastname: Lehmann
authors.forename: T A
authors.initials: TA
authors.lastname: Ban
mesh_terms: D014150:Antipsychotic Agents / Q000266:history*; D004409:Dyskinesia, Drug-Induced / Q000266:history*; D005260:Female; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000266:history*
chemical_list: D014150:Antipsychotic Agents