title: Effect of 3.0 mm tunnel and 6.0 mm corneoscleral incisions on the blood-aqueous barrier.
abstract: OBJECTIVE
  To study of the effect of silicone intraocular lens (IOL) implantation using a 3.0 mm tunnel incision with that of implantation though a 6.0 mm corneoscleral incision after phacoemulsification in human eyes.
  
  
  METHODS
  Department of Ophthalmology, University of Köln, Germany.
  
  
  METHODS
  In a prospective, randomized clinical study, 50 patients with senile cataract had phacoemulsification and IOL implantation through a 3.0 mm tunnel or a 6.0 mm corneoscleral incision. To assess blood-aqueous barrier (BAB) disruption, preoperative and postoperative sodium fluorescein concentrations in the anterior chamber were measured with the Fluorotron Master II. Diclofenac sodium 0.1% was applied to the operative eyes five times a day for 5 days. The contralateral eyes served as controls.
  
  
  RESULTS
  There was no significant between-group difference in sodium fluorescein concentrations in the 5 days after surgery.
  
  
  CONCLUSIONS
  The findings underline our clinical impression that BAB disruption 5 days after surgery does not differ significantly with the type and length of scleral incision used for IOL implantation.
authors.affiliation: Department of Ophthalmology, University of Köln, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Diestelhorst
authors.forename: S
authors.initials: S
authors.lastname: Dinslage
authors.forename: W
authors.initials: W
authors.lastname: Konen
authors.forename: G K
authors.initials: GK
authors.lastname: Krieglstein
mesh_terms: D000704:Analysis of Variance; D000867:Anterior Chamber / Q000098:blood supply; D001082:Aqueous Humor / Q000378:metabolism; D018916:Blood-Aqueous Barrier / Q000502:physiology*; D003315:Cornea / Q000502:physiology / Q000601:surgery*; D015590:Fluorophotometry; D005500:Follow-Up Studies; D006801:Humans; D007910:Lenses, Intraocular; D018918:Phacoemulsification / Q000379:methods*; D011183:Postoperative Complications; D011446:Prospective Studies; D012590:Sclera / Q000502:physiology / Q000601:surgery*; D013536:Suture Techniques