title: Acanthamoeba infection after radial keratotomy.
abstract: OBJECTIVE
  To describe a case of Acanthamoeba infection of the cornea after radial and astigmatic keratotomy.
  
  
  METHODS
  A 29-year-old man developed ulcerative keratitis in the right eye 6 weeks after uncomplicated radial and astigmatic keratotomy.
  
  
  RESULTS
  Three sets of corneal cultures for bacteria and fungi were negative. Culture on non-nutrient agar grew Acanthamoeba organisms. Clinical improvement occurred after topical antiamebic therapy was instituted.
  
  
  CONCLUSIONS
  Incisional keratotomy may predispose the cornea to delayed-onset infectious keratitis. Acanthamoeba should be considered as a possible cause of infection and should be cultured for in refractory cases.
authors.affiliation: Department of Ophthalmology, Dean A. McGee Eye Institute, USA.
authors.forename: R F
authors.initials: RF
authors.lastname: Friedman
authors.forename: T C
authors.initials: TC
authors.lastname: Wolf
authors.forename: J
authors.initials: J
authors.lastname: Chodosh
mesh_terms: D000048:Acanthamoeba / Q000302:isolation & purification; D015823:Acanthamoeba Keratitis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D000328:Adult; D000818:Animals; D000900:Anti-Bacterial Agents; D001251:Astigmatism / Q000601:surgery; D003315:Cornea / Q000469:parasitology / Q000601:surgery; D003320:Corneal Ulcer / Q000188:drug therapy / Q000469:parasitology* / Q000473:pathology; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D006801:Humans; D007646:Keratotomy, Radial / Q000009:adverse effects*; D008297:Male; D009883:Ophthalmic Solutions
chemical_list: D000900:Anti-Bacterial Agents; D009883:Ophthalmic Solutions