[Synovial fibroblasts from patients with rheumatoid arthritis transplanted in SCID mice destroy normal human cartilage and expressed VCAM-1 and cathepsins].
Kriegsmann
J
J
Institut für Pathologie, Friedrich-Schiller-Universität, Jena.
Müller-Ladner
U
U
Franklin
B N
BN
Matsumoto
S
S
Geiler
T
T
Gay
R E
RE
Bräuer
R
R
Katenkamp
D
D
Gay
S
S
D000818:Animals; D001172:Arthritis, Rheumatoid / Q000473:pathology / Q000503:physiopathology*; D002358:Cartilage, Articular; D002403:Cathepsins / Q000378:metabolism*; D017690:Cell Transplantation / Q000473:pathology; D006801:Humans; D051379:Mice; D016513:Mice, SCID; D012016:Reference Values; D013583:Synovial Membrane / Q000502:physiology* / Q000637:transplantation; D014183:Transplantation, Heterologous / Q000473:pathology; D019010:Vascular Cell Adhesion Molecule-1 / Q000378:metabolism*
D019010:Vascular Cell Adhesion Molecule-1; D002403:Cathepsins
Synoviale Fibroblasten von Patienten mit Rheumatoid-Arthritis (RA) transplantiert in SCID-Mäuse destruieren normalen menschlichen Knorpel und exprimieren VCAM-1 und Kathepsine.