title: Pityriasis rubra pilaris and focal acantholytic dyskeratosis.
abstract: A 65-year-old man presented with a widespread erythematous maculopapular eruption. Skin biopsy showed spongiosis and focal acantholytic dyskeratosis consistent with Grover's disease. Clinically the eruption evolved to erythroderma with typical features of pityriasis rubra pilaris. On review of the histology, changes consistent with this diagnosis were also present in addition to the acantholytic dyskeratosis.
authors.affiliation: Monash Medical Centre, Clayton, Victoria, Australia.
authors.forename: P
authors.initials: P
authors.lastname: Cowen
authors.forename: R
authors.initials: R
authors.lastname: O'Keefe
mesh_terms: D000051:Acantholysis / Q000150:complications* / Q000473:pathology; D000368:Aged; D001706:Biopsy; D003937:Diagnosis, Differential; D006801:Humans; D007642:Keratosis / Q000150:complications* / Q000473:pathology; D008297:Male; D010915:Pityriasis / Q000150:complications* / Q000473:pathology