title: 99mTc-HSA-D scintigraphy in the diagnosis of protein-losing gastroenteropathy due to secondary amyloidosis.
abstract: Secondary amyloidosis frequently involves the gastrointestinal tract and may result in ulceration, hemorrhage, and protein-losing enteropathy. We report a patient with severe hypoalbuminemia in whom endoscopy revealed widespread ulceration of the small intestine. The protein-losing site was detected by 99mTc-diethylene triamine pentaacetic acid human serum albumin (99mTc HSA-D) scintigraphy. This evidence suggests that the ulcers and mucosal lesions associated with amyloidosis contribute to abnormal protein loss from the gastrointestinal tract.
authors.affiliation: First Department of Internal Medicine, Yamaguchi University School of Medicine, Japan.
authors.forename: C
authors.initials: C
authors.lastname: Suzuki
authors.forename: S
authors.initials: S
authors.lastname: Higaki
authors.forename: M
authors.initials: M
authors.lastname: Nishiaki
authors.forename: N
authors.initials: N
authors.lastname: Mitani
authors.forename: H
authors.initials: H
authors.lastname: Yanai
authors.forename: M
authors.initials: M
authors.lastname: Tada
authors.forename: K
authors.initials: K
authors.lastname: Okita
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000150:complications*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D011504:Protein-Losing Enteropathies / Q000000981:diagnostic imaging* / Q000209:etiology; D011877:Radionuclide Imaging; D013668:Technetium Tc 99m Aggregated Albumin; D016284:Technetium Tc 99m Pentetate
chemical_list: D013668:Technetium Tc 99m Aggregated Albumin; C057162:technetium Tc 99m DTPA HSA; D016284:Technetium Tc 99m Pentetate