Efficacy of intravenous propafenone in termination of atrial flutter by overdrive transesophageal pacing previously ineffective.
Fifty patients with symptomatic type I atrial flutter in whom termination of the arrhythmia with transesophageal stimulation was unsuccessful were randomized to undergo a repeat procedure after intravenous propafenone (n = 25) or placebo (n = 25). Immediate sinus rhythm recovery rate was 36% in the propafenone group and 4% in the placebo group (p = 0.005), indicating that intravenous propafenone increases the rate of successful transesophageal stimulation and can be used when a first attempt at conversion is ineffective.
D'Este
D
D
Divisione di Cardiologia, O.C. Mirano.
Bertaglia
E
E
Mantovan
R
R
Zanocco
A
A
Franceschi
M
M
Pascotto
P
P
D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001282:Atrial Flutter / Q000628:therapy*; D004554:Electric Countershock / Q000379:methods*; D006339:Heart Rate; D006801:Humans; D008875:Middle Aged; D011405:Propafenone / Q000627:therapeutic use*; D011446:Prospective Studies; D016896:Treatment Outcome
D000889:Anti-Arrhythmia Agents; D011405:Propafenone