title: Novel reduction and hydroxylation products formed by Aspergillus fumigatus from Reichstein's substance S.
abstract: Fermentation of Reichstein's Substance S with Aspergillus fumigatus (AM-21) under aerobic conditions yielded 17 alpha, 21-dihydroxy-5 alpha-pregn-l-ene-3.20-dione. 17 alpha,20 alpha, 21-trihydroxy-5 alpha-pregn-l-en-3-one. 6 beta,17 alpha, 21-trihydroxypregn-4-en-3,20-dione. 15 beta,17 alpha,21-trihydroxy-5 alpha-pregnane-3,20-dione, and 15 beta, 17 alpha,20 alpha,21-tetrahydroxy-5 alpha-pregn-l-en-3-one. Each microbial metabolite was characterized by spectroscopic methods, including 13C NMR chemical shifts.
authors.affiliation: Indian Institute of Chemical Biology, Calcutta, India.
authors.forename: S
authors.initials: S
authors.lastname: Garai
authors.forename: S B
authors.initials: SB
authors.lastname: Mahato
mesh_terms: D001232:Aspergillus fumigatus / Q000378:metabolism*; D003350:Cortodoxone / Q000737:chemistry*; D005285:Fermentation; D006900:Hydroxylation; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D010084:Oxidation-Reduction; D013256:Steroids / Q000096:biosynthesis* / Q000737:chemistry
chemical_list: D013256:Steroids; D003350:Cortodoxone