title: Risk of endophthalmitis after cataract extraction: results from the International Cataract Surgery Outcomes study.
abstract: OBJECTIVE
  To estimate risk of infectious endophthalmitis after cataract extraction in Denmark and to compare results with the risk of this complication in the USA.
  
  
  METHODS
  In the national Danish administrative hospital register, 19,426 patients were identified who underwent first eye cataract surgery from 1985 to 1987 and who were 50 years of age or older. Of these, 61 patients had postoperative endophthalmitis.
  
  
  RESULTS
  A 12 month cumulative risk of rehospitalisation for endophthalmitis was estimated at 0.18% (95% CI 0.09-0.26) after extracapsular cataract extraction with lens implant. Advanced age, male sex, intracapsular cataract extraction, and anterior vitrectomy were all associated independently with an increased risk of postoperative endophthalmitis. When restricting the sample to patients aged 65 years or older, in order to allow comparisons to be made with the US National Study of Cataract Outcomes, a 12 month risk of 0.17% (95% CI 0.08-0.25) was estimated. The previously reported US risk of 0.12% is included in the confidence interval of the risk estimated in the Danish sample.
  
  
  CONCLUSIONS
  Despite considerable differences in the healthcare systems, no statistically significant difference in outcome of surgery as measured by risk of endophthalmitis was shown between Denmark and the USA.
authors.affiliation: Department of Social Medicine, Faculty of Health Science, University of Copenhagen, Denmark.
authors.forename: J C
authors.initials: JC
authors.lastname: Norregaard
authors.forename: H
authors.initials: H
authors.lastname: Thoning
authors.forename: P
authors.initials: P
authors.lastname: Bernth-Petersen
authors.forename: T F
authors.initials: TF
authors.lastname: Andersen
authors.forename: J C
authors.initials: JC
authors.lastname: Javitt
authors.forename: G F
authors.initials: GF
authors.lastname: Anderson
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction / Q000379:methods; D015331:Cohort Studies; D003718:Denmark; D009877:Endophthalmitis / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D011183:Postoperative Complications; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome; D014481:United States