The clinical applications of granulocyte colony-stimulating factor in hematopoietic stem cell transplantation: a review.
The administration of recombinant human granulocyte colony-stimulating factor (G-CSF) following chemotherapy, has been shown, in controlled randomized trials, to decrease the incidence of febrile neutropenic episodes, the duration of severe neutropenia and intravenous antimicrobial therapy, and the length of hospitalization. This review focuses on the evolving role of G-CSF in bone marrow and peripheral blood stem cell transplantation, and in hematopoietic stem cell mobilization.
Tabbara
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George Washington University, School of Medicine, Washington, DC 20037, USA.
Ghazal
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Ghazal
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D016026:Bone Marrow Transplantation; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D011994:Recombinant Proteins / Q000008:administration & dosage; D014182:Transplantation, Autologous
D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor