title: Medical therapy, calcium oxalate urolithiasis.
abstract: The development of diagnostic protocols that identify specific risk factors for calcium oxalate nephrolithiasis has led to the formulation of directed medical regimens that are aimed at correcting the underlying metabolic disturbances. Initiation of these treatment programs has reduced markedly the rate of stone formation in the majority of patients who form stones. This article discusses the rationale that underlies the choice of medical therapy for the various pathophysiologic causes of calcium oxalate nephrolithiasis and the appropriate use of available medications.
authors.affiliation: Center for Mineral Metabolism and Clinical Research, University of Texas, Southwestern Medical Center, Dallas, USA.
authors.forename: L A
authors.initials: LA
authors.lastname: Ruml
authors.forename: M S
authors.initials: MS
authors.lastname: Pearle
authors.forename: C Y
authors.initials: CY
authors.lastname: Pak
mesh_terms: D002118:Calcium / Q000652:urine; D002129:Calcium Oxalate; D002951:Citrates / Q000652:urine; D004032:Diet; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007668:Kidney / Q000002:abnormalities; D007669:Kidney Calculi / Q000737:chemistry / Q000209:etiology / Q000628:therapy* / Q000652:urine; D010070:Oxalates / Q000652:urine; D014527:Uric Acid / Q000652:urine
chemical_list: D002951:Citrates; D010070:Oxalates; D002129:Calcium Oxalate; D014527:Uric Acid; D002118:Calcium