Acute pancreatitis complicating a bone marrow harvest.
A patient developing acute pancreatitis with pseudocyst formation after an uncomplicated bone marrow harvest is reported. The diagnosis was confirmed by elevated serum amylase and lipase, and by CT scan. We suggest that the pancreatitis may have been precipitated by spasm of the sphincter of Oddi secondary to opiates administered as premedication and for pain relief.
Beamish
N
N
Clinical Haematology and Bone Marrow Transplant, Alfred Hospital, Melbourne, Australia.
Schwarer
A P
AP
Watson
A M
AM
Roberts
S
S
O'Brien
P
P
Morgan
B
B
D015746:Abdominal Pain / Q000139:chemically induced; D000208:Acute Disease; D000681:Amylases / Q000097:blood; D000701:Analgesics, Opioid / Q000009:adverse effects* / Q000494:pharmacology; D015415:Biomarkers; D001853:Bone Marrow; D016026:Bone Marrow Transplantation; D003061:Codeine / Q000009:adverse effects* / Q000494:pharmacology; D003137:Common Bile Duct Diseases / Q000139:chemically induced*; D006801:Humans; D008049:Lipase / Q000097:blood; D008297:Male; D008875:Middle Aged; D009892:Opium / Q000009:adverse effects* / Q000494:pharmacology; D010192:Pancreatic Pseudocyst / Q000097:blood / Q000209:etiology*; D010195:Pancreatitis / Q000097:blood / Q000209:etiology*; D011229:Preanesthetic Medication / Q000009:adverse effects*; D013035:Spasm / Q000139:chemically induced; D009803:Sphincter of Oddi / Q000187:drug effects; D014019:Tissue Donors
D000701:Analgesics, Opioid; D015415:Biomarkers; D009892:Opium; D008049:Lipase; D000681:Amylases; D003061:Codeine