[The effect of an inhibitor of chloride channels and of media with a decreased concentration of chlorine ions on the ovulation of oocytes in the common frog].
Ovulation of the Rana temporaria oocytes stimulated in vitro by the suspension of homologous pituitaries is suppressed by the chloride channel inhibitor SITS and media with reduced concentration of chloride ions. SITS and media with reduced concentration of chloride ions do not affect the progesterone-stimulated ovulation of oocytes. The mechanism of stimulating the effect of the gonadotropins on ovulation of the amphibian oocytes is discussed.
Skoblina
M N
MN
Kol'tsov Institute of Developmental Biology, Russian Academy of Sciences, Vavilova.
Kondrat'eva
O T
OT
Nikiforova
G P
GP
Huhtaniemi
I
I
D012856:4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid / Q000494:pharmacology*; D000818:Animals; D018118:Chloride Channels / Q000187:drug effects*; D002713:Chlorine / Q000008:administration & dosage*; D003470:Culture Media / Q000494:pharmacology*; D003864:Depression, Chemical; D004347:Drug Interactions; D005260:Female; D007552:Isotonic Solutions / Q000494:pharmacology; D009865:Oocytes / Q000187:drug effects*; D010060:Ovulation / Q000187:drug effects*; D010062:Ovulation Induction / Q000379:methods; D011896:Rana temporaria; D000077331:Ringer's Solution
D018118:Chloride Channels; D003470:Culture Media; D007552:Isotonic Solutions; D012856:4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; D002713:Chlorine; D000077331:Ringer's Solution
Vliianie ingibitora khornykh kanalov i sred so snizhennoĭ kontsentratsieĭ ionov khlora na ovuliatsiiu ootsitov travianoĭ liagushki.