[The participation of different types of opiate receptors in the mechanism of cardiac stressor damage].
The immobilisation stress was shown to induce a heart lesion. The agonist of peripheral mu-receptors DALDA was able to prevent the lesion, and natrexone--to diminish the stressor effect. Activation of the central mu-receptors seems to potentiate the stressor damaging effect, whereas activation of peripheral mu-receptors prevents the heart lesions.
Maslov
L N
LN
Lishmanov
Iu B
IuB
Naryzhnaia
N V
NV
D000818:Animals; D009202:Cardiomyopathies / Q000209:etiology* / Q000503:physiopathology; D009292:Narcotic Antagonists; D051381:Rats; D017208:Rats, Wistar; D011957:Receptors, Opioid / Q000819:agonists / Q000187:drug effects / Q000502:physiology*; D012149:Restraint, Physical; D013315:Stress, Psychological / Q000209:etiology* / Q000503:physiopathology; D013997:Time Factors
D009292:Narcotic Antagonists; D011957:Receptors, Opioid
Ob uchastii razlichnykh tipov opiatnykh retseptorov v mekhanizme stressornogo povrezhdeniia serdtsa.