title: Omeprazole-induced acute interstitial nephritis.
abstract: Omeprazole is a proton pump inhibitor widely used for the treatment of peptic ulcer disease. We report a patient presenting nonoliguric acute renal failure following omeprazole treatment. Both eosinophilia and eosinophiluria were observed, and the patient was diagnosed as having drug-induced acute interstitial nephritis. Renal failure spontaneously resolved when omeprazole was discontinued.
authors.affiliation: Nephrology and Dialysis Unit, Ospedale Santa Spirito, Rome, Italy.
authors.forename: G
authors.initials: G
authors.lastname: d'Adamo
authors.forename: C
authors.initials: C
authors.lastname: Spinelli
authors.forename: F
authors.initials: F
authors.lastname: Forte
authors.forename: F
authors.initials: F
authors.lastname: Gangeri
mesh_terms: D000208:Acute Disease; D000368:Aged; D000897:Anti-Ulcer Agents / Q000009:adverse effects*; D001706:Biopsy; D001806:Blood Urea Nitrogen; D003404:Creatinine / Q000097:blood; D004381:Duodenal Ulcer / Q000150:complications / Q000188:drug therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D009395:Nephritis, Interstitial / Q000097:blood / Q000139:chemically induced* / Q000473:pathology; D009853:Omeprazole / Q000009:adverse effects*
chemical_list: D000897:Anti-Ulcer Agents; D003404:Creatinine; D009853:Omeprazole