DNA damage induced in T50/80 tumour cells following exposure to the bioreductive drug Tirapazamine in combination with a single dose of radiation (12Gy).
Friery
O P
OP
School of Biomedical Sciences, University of Ulster, Jordanstown, N. Ireland.
Hejmadi
M V
MV
McKeown
S R
SR
D000818:Animals; D004249:DNA Damage; D004273:DNA, Neoplasm / Q000187:drug effects* / Q000528:radiation effects*; D008297:Male; D008325:Mammary Neoplasms, Experimental / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology / Q000532:radiotherapy; D051379:Mice; D008815:Mice, Inbred Strains; D011838:Radiation-Sensitizing Agents / Q000494:pharmacology* / Q000627:therapeutic use; D013997:Time Factors; D000077704:Tirapazamine; D014227:Triazines / Q000494:pharmacology* / Q000627:therapeutic use; D014965:X-Rays
D004273:DNA, Neoplasm; D011838:Radiation-Sensitizing Agents; D014227:Triazines; D000077704:Tirapazamine