Forensic analysis of 10 barbiturates in human biological samples using a new reversed-phase chromatographic column packed with 2-micrometre porous microspherical silica-gel.
A high-performance liquid chromatographic method has been developed for the forensic analysis of 10 frequently used barbiturates (BARs) (allobarbital, amobarbital, barbital, cyclobarbital, hexobarbital, metharbital, pentobarbital, phenobarbital, secobarbital and thiopental) using a recently developed reversed-phase column packed with 2-micron particles. The results show that the new ODS column packing gives higher sensitivity and a shorter analysis time than the conventional ODS column packing when applied to the analysis of biological samples.
Tanaka
E
E
Department of Legal Medicine, University of Tsukuba, Japan.
Terada
M
M
Tanno
K
K
Misawa
S
S
Wakasugi
C
C
D001344:Autopsy; D001463:Barbiturates / Q000032:analysis / Q000097:blood* / Q000652:urine*; D001923:Brain Chemistry; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006801:Humans; D008099:Liver / Q000737:chemistry*; D008863:Microspheres
D001463:Barbiturates