Evaluation of predictive factors for multiple pregnancies during gonadotropin/IUI treatment.
OBJECTIVE
Our purpose was to analyze factors for their predictability of multiple pregnancies in patients treated with a combination of human menopausal gonadotropins (hMG) and intrauterine insemination (IUI).


METHODS
The records of all patients conceiving through treatment with hMG/IUI were reviewed for factors predictive of multiple pregnancy.


RESULTS
Ninety-one pregnancies reviewed included 78 singleton (86%), 8 twin (9%), and 5 higher-order pregnancies (5%). The total number of follicles > 10 mm was greater in the multiple-pregnancy group and there was a decreased number of postwash sperm in the multiple-pregnancy group. Otherwise there was no significant difference in the factors analyzed.


CONCLUSIONS
No factor or combination of factors predicts multiple pregnancies to a degree that it would be helpful in managing or counseling patients.
Goldfarb
J M
JM
Department of Ob/Gyn, University Hospitals of Cleveland, Case Western Reserve University, Ohio 44106, USA.
Peskin
B
B
Austin
C
C
Lisbona
H
H
D005260:Female; D005300:Fertility Agents, Female / Q000627:therapeutic use*; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy* / Q000209:etiology; D007315:Insemination, Artificial; D008596:Menotropins / Q000627:therapeutic use*; D011247:Pregnancy; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple; D012306:Risk
D005300:Fertility Agents, Female; D008596:Menotropins