title: Charcot knee arthropathy with articular amyloid deposition in familial amyloidotic polyneuropathy.
abstract: An extremely rare case of familial amyloidotic polyneuropathy (FAP) complicated by neuroarthropathy (Charcot joint) in the left knee joint and by intra-articular deposits of amyloid was observed. FAP-specific variant transthyretin (TTR) was found in the synovial fluid and amyloid deposits were confirmed in the synovium, cartilage and bone by Congo red staining and immuno-staining.
authors.affiliation: Department of Orthopaedic Surgery, Kumamoto University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Shiraishi
authors.forename: Y
authors.initials: Y
authors.lastname: Ando
authors.forename: H
authors.initials: H
authors.lastname: Mizuta
authors.forename: E
authors.initials: E
authors.lastname: Nakamura
authors.forename: K
authors.initials: K
authors.lastname: Takagi
authors.forename: M
authors.initials: M
authors.lastname: Ando
mesh_terms: D000328:Adult; D000682:Amyloid / Q000032:analysis*; D017772:Amyloid Neuropathies / Q000473:pathology*; D001177:Arthropathy, Neurogenic / Q000473:pathology*; D006801:Humans; D007719:Knee Joint; D008297:Male
chemical_list: D000682:Amyloid