[The role of serotonin in the effects of cholecystokinin-8 on memory in rats].
The HCK8 was found to inhibit the field search behaviour in rats. Administration of the peptide impairs formation and reproduction of a habit within 1 hour and 24 hrs. The data obtained suggest an important role of the brain monoaminergic systems in the mechanisms of the HCK8 effect upon learning and memory.
Semenova
T P
TP
Ivanov
D A
DA
Medvinskaia
N I
NI
D006916:5-Hydroxytryptophan / Q000494:pharmacology; D000818:Animals; D001362:Avoidance Learning / Q000187:drug effects / Q000502:physiology; D001923:Brain Chemistry / Q000187:drug effects / Q000502:physiology; D002395:Catecholamines / Q000032:analysis; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology; D005106:Exploratory Behavior / Q000187:drug effects / Q000502:physiology; D006897:Hydroxyindoleacetic Acid / Q000032:analysis; D008297:Male; D008568:Memory / Q000187:drug effects* / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D012701:Serotonin / Q000032:analysis / Q000502:physiology*; D012844:Sincalide / Q000494:pharmacology*
D002395:Catecholamines; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D006916:5-Hydroxytryptophan; D012844:Sincalide
Rol' serotonina v éffektakh kholetsistokinina-8 na pamiat' krys.