Embolism of fetal brain tissue to the lungs and the placenta.
We describe a case of a 19-year-old G1P0 woman with an unremarkable prenatal course who presented at term in labor. Fetal bradycardia developed and forceps were used to deliver a male infant, who was born with Apgar scores of 0 and 0 and could not be resuscitated. Examination at autopsy revealed no gross evidence of trauma, but on microscopic examination of the lungs and the placenta, multiple fetal vessels contained emboli consisting of fragments of fetal cerebellar cortex. Previously reported cases of this rare phenomenon are reviewed and the pathogenesis is discussed.
Baergen
R N
RN
Department of Pathology, University of California, San Diego, USA.
Castillo
M M
MM
Mario-Singh
B
B
Stehly
A J
AJ
Benirschke
K
K
D000328:Adult; D001921:Brain; D002828:Choristoma / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008171:Lung Diseases / Q000473:pathology*; D008297:Male; D010922:Placenta Diseases / Q000473:pathology*; D011247:Pregnancy; D011655:Pulmonary Embolism / Q000473:pathology*