Charcot knee arthropathy with articular amyloid deposition in familial amyloidotic polyneuropathy.
An extremely rare case of familial amyloidotic polyneuropathy (FAP) complicated by neuroarthropathy (Charcot joint) in the left knee joint and by intra-articular deposits of amyloid was observed. FAP-specific variant transthyretin (TTR) was found in the synovial fluid and amyloid deposits were confirmed in the synovium, cartilage and bone by Congo red staining and immuno-staining.
Shiraishi
M
M
Department of Orthopaedic Surgery, Kumamoto University School of Medicine, Japan.
Ando
Y
Y
Mizuta
H
H
Nakamura
E
E
Takagi
K
K
Ando
M
M
D000328:Adult; D000682:Amyloid / Q000032:analysis*; D017772:Amyloid Neuropathies / Q000473:pathology*; D001177:Arthropathy, Neurogenic / Q000473:pathology*; D006801:Humans; D007719:Knee Joint; D008297:Male
D000682:Amyloid