title: Learning without performance in PKC-deficient Drosophila.
abstract: The performance of a task is often assumed to be a prerequisite for the learning of many tasks, including the associative conditioning of courtship in the fruit fly, Drosophila melanogaster. Transgenic flies specifically inhibited for the enzyme protein kinase C dissociate the acquisition of learning and memory from performance of the task. They fail to show immediate suppression of courtship but nonetheless develop normal memory of it.
authors.affiliation: Department of Biology and Center for Neural Science, New York University, New York, New York 10003, USA.
authors.forename: N S
authors.initials: NS
authors.lastname: Kane
authors.forename: A
authors.initials: A
authors.lastname: Robichon
authors.forename: J A
authors.initials: JA
authors.lastname: Dickinson
authors.forename: R J
authors.initials: RJ
authors.lastname: Greenspan
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D003213:Conditioning, Psychological / Q000502:physiology*; D004331:Drosophila melanogaster; D005260:Female; D007858:Learning / Q000502:physiology*; D008124:Locomotion / Q000502:physiology; D008297:Male; D008568:Memory / Q000502:physiology*; D011493:Protein Kinase C / Q000172:deficiency / Q000502:physiology*; D012153:Retention, Psychology / Q000502:physiology; D012726:Sexual Behavior, Animal / Q000502:physiology*; D012903:Smell / Q000502:physiology
chemical_list: D011493:Protein Kinase C