title: [Xanthogranulomatous cholecystitis simulating gallbladder neoplasm: therapeutic implications].
abstract: Xanthogranulomatous cholecystitis (XGC) is an infrequent type of chronic cholecystitis whose histologic features, in some cases, show a macroscopic appearance which may lead to suspicion of a gallbladder neoplasm with the consequent contraindication of the laparoscopic approach. The incidence of XGC was reviewed in a prospective series of 514 cholecystectomies performed in the authors' department from January 1991 to January 1996. Fourteen cases (2.7%) of XGC were identified with a male/female ratio of 1/1.8 and a mean age of 71 +/- 9 years. The most frequent form of presentation observed was hepatic cholic (43%). Echography showed cholelithiasis in 13 patients (93%). In 3 cases (21%), clinical and echographic suspicion of neoplasm was established, two being in the gallbladder, thus contraindicating the laparoscopic approach. A third patient underwent surgery for suspicion of a colon neoplasm. Xanthogranulomatous cholecystitis presents a macroscopic appearance which may be interpreted as a gallbladder neoplasm in up to 25% of the cases thus leading to treatment with laparoscopy.
authors.affiliation: Servicio de Cirugía General y del Aparato Digestivo, Hospital Clínic i Provincial, Universidad de Barcelona.
authors.forename: C
authors.initials: C
authors.lastname: Balagué
authors.forename: E M
authors.initials: EM
authors.lastname: Targarona
authors.forename: G
authors.initials: G
authors.lastname: Sugrañes
authors.forename: M J
authors.initials: MJ
authors.lastname: Rey
authors.forename: Y
authors.initials: Y
authors.lastname: Arce
authors.forename: P
authors.initials: P
authors.lastname: Viella
authors.forename: M
authors.initials: M
authors.lastname: Trias
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002763:Cholecystectomy; D002764:Cholecystitis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005704:Gallbladder / Q000473:pathology; D005706:Gallbladder Neoplasms / Q000175:diagnosis*; D006099:Granuloma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography; D014973:Xanthomatosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology
vernacular_title: Colecistitis xantogranulomatosa simulando una neoplasia de vesícula: implicaciones terapéuticas.