[The role of G-proteins and second messenger systems in the plasticity of the avoidance reflex in the snail].
An increase in the activity of G-proteins and protein kinase A was shown in the brain of Helix at the early stages of learning. The protein kinase C activity did not differ from the baseline in 20-40 min after training. There was no difference between the brain G-protein activities in the young (unable to learn) and adult snails. A conclusion is drawn that the system of cAMP-dependent phosphorylation and cAMP-dependent activation of the early genes actively participate in learning of Helix. The participation of additional systems of intracellular regulation in learning is discussed.
Grinkevich
L N
LN
Toporkova
L B
LB
Lisachev
P D
PD
Izvarina
N L
NL
D000375:Aging / Q000502:physiology; D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D001921:Brain / Q000502:physiology; D003214:Conditioning, Classical / Q000502:physiology*; D017868:Cyclic AMP-Dependent Protein Kinases / Q000502:physiology; D019204:GTP-Binding Proteins / Q000502:physiology*; D006372:Helix, Snails / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology*; D011493:Protein Kinase C / Q000502:physiology; D015290:Second Messenger Systems / Q000502:physiology*
D017868:Cyclic AMP-Dependent Protein Kinases; D011493:Protein Kinase C; D019204:GTP-Binding Proteins
Rol' G-belkov i sistem vtorichnykh posrednikov v plastichnosti oboronitel'nogo refleksa u vinogradnoĭ ulitki.