Further observation of leucocyte migration through the endothelium of venules in the posterior latissimus dorsi muscle of the quail-chick spinal cord chimeras.
The migration of leucocytes through the walls of venules was examined in detail in the posterior latissimus dorsi muscle of quail-chick spinal cord chimeras, in which flaccid paralysis of the wings was observed. Examinations were made from the 70th to 80th day after hatching. Muscle fibers were degenerated and intramuscular nerve bundles destroyed. Massive leucocytes (almost lymphocytes) were found around the venules, depending on the passage of wandering leucocytes through the endothelium. Lymphocytes penetrated and were encased in the cytoplasm of the venular endothelial cell, and did not pass through the interendothelial junction. These findings suggest that, in the venules of the atrophied chimeric muscle, wandering leucocytes in the blood may pass through the endothelial cell body and migrate into the inflamed extravascular space.
Desaki
J
J
Department of Anatomy, Ehime University School of Medicine, Japan.
Kinutani
M
M
Tan-Takeuchi
K
K
Le Douarin
N M
NM
D000818:Animals; D001284:Atrophy; D002465:Cell Movement / Q000276:immunology*; D002645:Chickens; D002678:Chimera; D003370:Coturnix; D003593:Cytoplasm / Q000276:immunology; D004730:Endothelium, Vascular / Q000276:immunology*; D007365:Intercellular Junctions / Q000276:immunology; D007962:Leukocytes / Q000166:cytology*; D018485:Muscle Fibers, Skeletal / Q000473:pathology; D009123:Muscle Hypotonia; D018482:Muscle, Skeletal / Q000098:blood supply / Q000276:immunology* / Q000473:pathology; D010243:Paralysis / Q000473:pathology; D013116:Spinal Cord; D014699:Venules; D014921:Wings, Animal