Olsalazine-induced lupus syndrome.
A 73 year-old woman with ulcerative colitis developed skin rashes after long-standing sulphasalazine treatment. After a switch to olsalazine, she developed a severe SLE with multiorgan involvement. When the treatment was terminated, the disease manifestations and serological findings resolved.
Gunnarsson
I
I
Department of Rheumatology, Karolinska Hospital, Stockholm, Sweden.
Pettersson
E
E
Lindblad
S
S
Ringertz
B
B
D000368:Aged; D000636:Aminosalicylic Acids / Q000009:adverse effects* / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced*
D000636:Aminosalicylic Acids; C032587:olsalazine