title: Forensic analysis of 10 barbiturates in human biological samples using a new reversed-phase chromatographic column packed with 2-micrometre porous microspherical silica-gel.
abstract: A high-performance liquid chromatographic method has been developed for the forensic analysis of 10 frequently used barbiturates (BARs) (allobarbital, amobarbital, barbital, cyclobarbital, hexobarbital, metharbital, pentobarbital, phenobarbital, secobarbital and thiopental) using a recently developed reversed-phase column packed with 2-micron particles. The results show that the new ODS column packing gives higher sensitivity and a shorter analysis time than the conventional ODS column packing when applied to the analysis of biological samples.
authors.affiliation: Department of Legal Medicine, University of Tsukuba, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Tanaka
authors.forename: M
authors.initials: M
authors.lastname: Terada
authors.forename: K
authors.initials: K
authors.lastname: Tanno
authors.forename: S
authors.initials: S
authors.lastname: Misawa
authors.forename: C
authors.initials: C
authors.lastname: Wakasugi
mesh_terms: D001344:Autopsy; D001463:Barbiturates / Q000032:analysis / Q000097:blood* / Q000652:urine*; D001923:Brain Chemistry; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D006801:Humans; D008099:Liver / Q000737:chemistry*; D008863:Microspheres
chemical_list: D001463:Barbiturates