title: Iridial hypoplasia (aniridia) accompanied by limbic dermoids and cataracts in a group of related quarterhorses.
abstract: The clinical, gross and microscopic ophthalmic lesions of iridial hypoplasia, limbic dermoids and cataracts in a Quarterhorse stallion and a group of its offspring are described. It is proposed that the lesions in the stallion were the result of an independent mutation and that the defects were transmitted to its offspring by an autosomal dominant gene.
authors.affiliation: Department of Veterinary Large Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station 77843, USA.
authors.forename: J R
authors.initials: JR
authors.lastname: Joyce
authors.forename: J E
authors.initials: JE
authors.lastname: Martin
authors.forename: R W
authors.initials: RW
authors.lastname: Storts
authors.forename: L
authors.initials: L
authors.lastname: Skow
mesh_terms: D000818:Animals; D015783:Aniridia / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D002386:Cataract / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D003884:Dermoid Cyst / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D005134:Eye Neoplasms / Q000235:genetics / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases / Q000235:genetics* / Q000473:pathology; D006736:Horses; D007498:Iris / Q000002:abnormalities* / Q000473:pathology; D007908:Lens, Crystalline / Q000473:pathology; D008297:Male