title: MRI of primary meningeal sarcomas in two children: differential diagnostic considerations.
abstract: Meningeal sarcomas are very rare, highly aggressive tumours affecting children more frequently than adults. The clinical course and MRI of meningeal sarcomas in two cases are discussed with special regard to possible misinterpretation. In one case MRI demonstrated a circumscribed mass in contact with the meninges, with central areas of haemorrhage. In the other, a case of primary leptomeningeal sarcomatosis, several MRI examinations over the course of almost a year were unhelpful, despite severe neurological complaints. Then MRI revealed meningeal contrast enhancement all over the brain and spinal canal, together with cerebral infarcts. MRI of meningeal sarcomas has not been discussed in the literature. MRI did not permit specific diagnosis, but enabled visualisation of the extent of the tumour and/or meningeal involvement. Early histological diagnosis is indispensable for adequate treatment.
authors.affiliation: Department of Radiology, Klinikum Innenstadt, University of Munich, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Pfluger
authors.forename: S
authors.initials: S
authors.lastname: Weil
authors.forename: S
authors.initials: S
authors.lastname: Weis
authors.forename: K
authors.initials: K
authors.lastname: Bise
authors.forename: J
authors.initials: J
authors.lastname: Egger
authors.forename: H B
authors.initials: HB
authors.lastname: Hadorn
authors.forename: K
authors.initials: K
authors.lastname: Hahn
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D008578:Meninges / Q000473:pathology; D008579:Meningioma / Q000175:diagnosis* / Q000473:pathology