title: Complete sequence of SpHox8 and its linkage in the single Hox gene cluster of Strongylocentrotus purpuratus.
abstract: SpHox8 is the paralog group 8 Hox gene of Strongylocentrotus purpuratus. This identification follows from an analysis of the sequence of the complete open reading frame of a late-gastrula-stage cDNA clone; from direct linkage to adjacent Hox genes in a fosmid contig; and from blot hybridizations carried out on pulse field gel electrophoretic separations. SpHox8 is a single-copy gene, and there is only one Hox gene cluster per genome in S. purpuratus.
authors.affiliation: Division of Biology 156-29, California Institute of Technology, Pasadena, CA 91125, USA.
authors.forename: P
authors.initials: P
authors.lastname: Martinez
authors.forename: J C
authors.initials: JC
authors.lastname: Lee
authors.forename: E H
authors.initials: EH
authors.lastname: Davidson
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D017124:Conserved Sequence; D017931:DNA Primers; D018076:DNA, Complementary; D005801:Genes, Homeobox; D008040:Genetic Linkage; D018398:Homeodomain Proteins / Q000737:chemistry / Q000235:genetics*; D008969:Molecular Sequence Data; D005810:Multigene Family; D011994:Recombinant Proteins / Q000737:chemistry; D012617:Sea Urchins / Q000235:genetics*; D017386:Sequence Homology, Amino Acid
chemical_list: D017931:DNA Primers; D018076:DNA, Complementary; D018398:Homeodomain Proteins; D011994:Recombinant Proteins; C105702:SpHox8 protein, Strongylocentrotus purpuratus