[Coinfection of hepatitis C virus and hepatitis G virus in patients with chronic hepatitis].
Hepatitis G virus(HGV) has been cloned and it is associated with liver diseases. We reported the influence of HGV infection on clinical features of patients with chronic hepatitis C. Subjects were 262 patients with HCV RNA. Detection of HGV RNA was performed by RT-PCR using specific primers from the NS5 regions. Of 262 patients, 28(11%) were positive HGV. No significant differences were detected in liver functions tests, histological examination and efficacy of interferon treatment between HGV-positive and HGV-negative patients with chronic hepatitis C. In conclusions, HGV infection did not influence clinical features of patients with chronic HCV infection.
Oshita
M
M
First Department of Medicine, Osaka University School of Medicine.
Mita
E
E
Hayashi
N
N
D000328:Adult; D015415:Biomarkers / Q000097:blood; D002908:Chronic Disease; D005260:Female; D018067:Flaviviridae / Q000235:genetics / Q000302:isolation & purification; D006526:Hepatitis C / Q000150:complications* / Q000628:therapy / Q000821:virology; D006525:Hepatitis, Viral, Human / Q000150:complications* / Q000628:therapy / Q000821:virology; D006801:Humans; D007372:Interferons / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012367:RNA, Viral / Q000097:blood
D015415:Biomarkers; D012367:RNA, Viral; D007372:Interferons