Architecture of helix bundle membrane proteins: an analysis of cytochrome c oxidase from bovine mitochondria.
We have analyzed the structure of mitochondrial cytochrome c oxidase in terms of general characteristics thought to be important for describing the architecture of helix bundle membrane proteins. Many aspects of the structure are similar to what has previously been found for the photosynthetic reaction center and bacteriorhodopsin. Our results lead to a considerably more precise general picture of membrane protein architecture than has hitherto been possible to obtain.
Wallin
E
E
Department of Biochemistry, Stockholm University, Sweden.
Tsukihara
T
T
Yoshikawa
S
S
von Heijne
G
G
Elofsson
A
A
D000596:Amino Acids / Q000737:chemistry; D000818:Animals; D001436:Bacteriorhodopsins / Q000737:chemistry; D002417:Cattle; D003576:Electron Transport Complex IV / Q000737:chemistry*; D008565:Membrane Proteins / Q000737:chemistry*; D008928:Mitochondria / Q000201:enzymology*; D045322:Photosynthetic Reaction Center Complex Proteins / Q000737:chemistry; D011487:Protein Conformation
D000596:Amino Acids; D008565:Membrane Proteins; D045322:Photosynthetic Reaction Center Complex Proteins; D001436:Bacteriorhodopsins; D003576:Electron Transport Complex IV