title: Rickets in a litter of racing greyhounds.
abstract: Rickets was diagnosed in six 14-week-old racing greyhound littermates presented with musculoskeletal disease. Physical findings included listlessness, profound muscle weakness, lameness, lateral bowing of the antebrachii and focal hard swellings proximal to the tarsi and carpi. Radiological findings included generalised osteopenia, axial and radial thickening of growth plates, and "cupping' of the adjacent metaphyses; the distal ulnar growth plates were most severely and consistently affected. The diagnosis was confirmed by demonstrating subnormal concentrations of 25-hydroxycholecalciferol in serum samples collected at admission. The pups' diet consisted of an inexpensive generic kibble formulated for adult dogs, porridge, milk, pasta, minced beef, vegetables and a small quantity of calcium carbonate powder. The pups were successfully treated by feeding a nutritionally complete, vitamin D-containing ration formulated for growing pups. Bilateral growth retardation of distal ulnar physes occurred as a sequel in one pup.
authors.affiliation: Department of Veterinary Clinical Sciences, University of Sydney, New South Wales, Australia.
authors.forename: R
authors.initials: R
authors.lastname: Malik
authors.forename: C
authors.initials: C
authors.lastname: Laing
authors.forename: P E
authors.initials: PE
authors.lastname: Davis
authors.forename: G S
authors.initials: GS
authors.lastname: Allan
authors.forename: D I
authors.initials: DI
authors.lastname: Wigney
mesh_terms: D000818:Animals; D002112:Calcifediol / Q000097:blood; D002350:Carpus, Animal / Q000000981:diagnostic imaging / Q000473:pathology; D004032:Diet / Q000592:standards / Q000662:veterinary; D004283:Dog Diseases / Q000175:diagnosis* / Q000235:genetics* / Q000503:physiopathology; D004285:Dogs; D005260:Female; D006132:Growth Plate / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D011859:Radiography / Q000379:methods / Q000662:veterinary; D012279:Rickets / Q000175:diagnosis / Q000235:genetics / Q000662:veterinary*; D013177:Sports; D013643:Tarsus, Animal / Q000000981:diagnostic imaging / Q000473:pathology; D014457:Ulna / Q000000981:diagnostic imaging / Q000473:pathology; D014807:Vitamin D / Q000627:therapeutic use
chemical_list: D014807:Vitamin D; D002112:Calcifediol