title: [Determination of cardiac troponin I on Stratus analyzer: prospective evaluation in unstable angina].
abstract: Cardiac troponin I (troponin lc) has been measured on the Dade Stratus analyzer. Cardiac specificity has been studied in patients presenting a rhabdomyolysis syndrome. The obtained results clearly demonstrated that this parameter may be used as a specific marker of myocardial injury, in contrast to total creatine kinase- or mass CK-MB measurements. In unstable angina, two groups of patients may be defined: one group with elevated troponin lc (> 0.60 microgram/L; 31 patients, group I), one other with normal troponin lc (< 0.35 microgram/L; 49 patients; group II). Quantitative angiographic analysis was performed on 50 patients including 18 patients from group I. Group I showed a more severe culprit lesion than group II. All the results suggested that troponin Ic might be an indicator of severity in unstable angina.
authors.affiliation: Laboratoire de biochimie, hôpital Charles-Nicolle, Rouen France.
authors.forename: M
authors.initials: M
authors.lastname: Quillard
authors.forename: R
authors.initials: R
authors.lastname: Koning
authors.forename: H
authors.initials: H
authors.lastname: Andres
authors.forename: B
authors.initials: B
authors.lastname: Cauliez
authors.forename: G
authors.initials: G
authors.lastname: Hue
authors.forename: B
authors.initials: B
authors.lastname: Letac
authors.forename: F
authors.initials: F
authors.lastname: Matray
authors.forename: A
authors.initials: A
authors.lastname: Lavoinne
mesh_terms: D000328:Adult; D000789:Angina, Unstable / Q000097:blood* / Q000150:complications; D003402:Creatine Kinase / Q000032:analysis / Q000097:blood; D005260:Female; D015200:Fluoroimmunoassay; D006801:Humans; D007527:Isoenzymes; D008297:Male; D011446:Prospective Studies; D012206:Rhabdomyolysis / Q000150:complications; D019210:Troponin I / Q000097:blood*
chemical_list: D007527:Isoenzymes; D019210:Troponin I; D003402:Creatine Kinase
vernacular_title: Dosage de la troponine I cardiaque sur l'automate Stratus: évaluation prospective dans I'angor instable.