title: Migration of small and large cells from the grafts of embryonic olfactory bulbs, transplanted into the anterior wall of the lateral ventricle.
abstract: Embryonic olfactory bulbs (OBs) were transplanted into the anterior wall of the lateral ventricle (ALV) of juvenile and adult host mice. Neurons originated from the transplanted OBs were detected immunohistochemically by using mouse Thy-1 allelic system. Within the OBs of both host groups, a substantial number of Thy-1.2-positive small presumed granule cells were observed. Furthermore, Thy-1.2 labeled large cells, although far smaller in number, were encountered in some cortical areas, including the anterior olfactory nucleus of the juvenile host group, but not within the host OBs. These results indicated that both small and large cell precursors had the capacity to migrate from the host ALV, but only the small cell precursors could migrate tangentially into host OBs.
authors.affiliation: Laboratory of human science, Hamamatsu University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Fujii
authors.forename: K
authors.initials: K
authors.lastname: Kosaka
mesh_terms: D000818:Animals; D016380:Brain Tissue Transplantation / Q000502:physiology*; D002465:Cell Movement; D002552:Cerebral Ventricles / Q000502:physiology*; D016332:Fetal Tissue Transplantation / Q000502:physiology*; D051379:Mice; D008806:Mice, Inbred AKR; D008807:Mice, Inbred BALB C; D009474:Neurons / Q000166:cytology / Q000502:physiology*; D009830:Olfactory Bulb / Q000502:physiology* / Q000637:transplantation*; D018800:Thy-1 Antigens / Q000032:analysis; D014184:Transplantation, Homologous
chemical_list: D018800:Thy-1 Antigens