[Surgical technique and results of bilateral volume reduction in patients with pulmonary emphysema].
Between 9/94 and 3/96 volume reduction was performed on 29 patients by a median sternotomy or videoendoscopic approach. Perioperative mortality occurred in three patients. The residual volume decreased within the first month from preoperative 308.8 +/- 13.4% of predicted (%p) to 217.9 +/- 12.7%p (p < 0.05). FeV1 significantly improved to 37.9 +/- 4.6%p after 3 months, versus 23.5 +/- 1.8%p preoperatively (p < 0.05). Intrinsic PEEP substantially decreased from 6.69 +/- 0.91 cm H2O preop to 0.93 +/- 0.28 cm H2O initially after surgery (p < 0.005). This was paralleled by the work of breathing: 1.78 +/- 0.2 J/l preoperatively versus 0.77 +/- 0.04 J/l postoperatively (p < 0.005). In conclusion, VR is a safe and successful option for patients with pulmonary emphysema, who show signs of marked hyperinflation.
Wisser
W
W
Abt. f. Herz-Thoraxchirurgie, Univ.-Klinik f. Chirurgie, Universität Wien.
Tschernko
E
E
Wanke
T
T
Kontrus
M
M
Senbacklavaci
O
O
Wolner
E
E
Klepetko
W
W
D005260:Female; D006801:Humans; D008168:Lung / Q000503:physiopathology; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D011013:Pneumonectomy / Q000379:methods*; D011183:Postoperative Complications / Q000401:mortality / Q000503:physiopathology; D011656:Pulmonary Emphysema / Q000401:mortality / Q000503:physiopathology / Q000601:surgery*; D015996:Survival Rate; D016896:Treatment Outcome
D010100:Oxygen
Operative Technik und Ergebnisse nach bilateraler Volumenreduktion bei Patienten mit Lungenemphysem.