Changes in plasma prolactin and catecholamine metabolite levels following acute needle stick in children.
Changes in plasma levels of prolactin (PRL), homovanillic acid (HVA), and 3-methoxy-4-hydroxyphenylglycol (MHPG) following insertion of an indwelling catheter into a forearm vein were assessed in 11 boys with attention-deficit hyperactivity disorder. Results indicated decreases in plasma PRL and HVA, but not MHPG, from the time of needle stick until 105 min post-insertion. These data indicate a significant increase in plasma PRL and HVA in children following needle stick which gradually decreases over a 1.5-2-h period. These stress-induced changes indicate that values obtained immediately after needle insertion cannot be assumed to accurately reflect baseline levels.
Grayson
R H
RH
Department of Psychology, Queens College, Flushing, NY, USA.
Halperin
J M
JM
Sharma
V
V
Schwartz
S T
ST
Koda
V H
VH
Newcorn
J H
JH
D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis / Q000523:psychology; D002408:Catheters, Indwelling; D002648:Child; D006719:Homovanillic Acid / Q000097:blood*; D006801:Humans; D008297:Male; D008734:Methoxyhydroxyphenylglycol / Q000097:blood*; D016602:Needlestick Injuries / Q000097:blood*; D011388:Prolactin / Q000097:blood*; D013997:Time Factors
D008734:Methoxyhydroxyphenylglycol; D011388:Prolactin; D006719:Homovanillic Acid