Hyperkalemic periodic paralysis.
Hyperkalemic periodic paralysis is an autosomal codominant genetic disease of horses who are descendants of the quarter horse sire Impressive. It produces a muscular phenotype that has been selected by show judges, which has resulted in the rapid dissemination of this disease. Clinical attacks are characterized by muscle fasciculation and spasm, and they respond to treatments for the concurrent hyperkalemia.
Naylor
J M
JM
Department of Veterinary Internal Medicine, University of Saskatchewan, Western College of Veterinary Medicine, Saskatoon, Canada.
D000818:Animals; D004576:Electromyography / Q000379:methods / Q000662:veterinary; D005260:Female; D005820:Genetic Testing / Q000379:methods / Q000662:veterinary; D006734:Horse Diseases / Q000235:genetics / Q000503:physiopathology / Q000628:therapy; D006736:Horses; D006947:Hyperkalemia / Q000235:genetics / Q000503:physiopathology / Q000662:veterinary*; D008297:Male; D009140:Musculoskeletal Diseases / Q000235:genetics / Q000503:physiopathology / Q000662:veterinary*; D010243:Paralysis / Q000235:genetics / Q000503:physiopathology / Q000662:veterinary*; D010375:Pedigree; D010507:Periodicity; D012641:Selection, Genetic