[Piracetam and tocopherol acetate ability to potentiate clinical effect of antianginal drugs in presenile and senile patients with ischemic heart disease (unstable angina)].
Potentiating ability of piracetam and tocopherol acetate was studied outpatiently in aged patients with ischemic heart disease. It was found that the addition of piracetam and tocopherol acetate to conventional antianginal drug therapy brings higher response and exercise tolerance, contributes to more effective hemodynamic and energetic support of the exercise, to positive changes in the central and peripheral hemodynamics.
Pimenov
L T
LT
Department of Polyclinic Therapy, State Medical Academy, Izhevsk.
Churshin
A D
AD
Ezhov
A V
AV
D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D000368:Aged; D000369:Aged, 80 and over; D000789:Angina, Unstable / Q000188:drug therapy* / Q000503:physiopathology; D000975:Antioxidants / Q000008:administration & dosage / Q000627:therapeutic use*; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000627:therapeutic use; D004333:Drug Administration Routes; D004357:Drug Synergism; D004359:Drug Therapy, Combination; D015716:Electrocardiography, Ambulatory; D006801:Humans; D008875:Middle Aged; D018696:Neuroprotective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D010889:Piracetam / Q000008:administration & dosage / Q000627:therapeutic use*; D024505:Tocopherols; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000008:administration & dosage / Q000627:therapeutic use; D014810:Vitamin E / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D024502:alpha-Tocopherol / Q000031:analogs & derivatives*
D000319:Adrenergic beta-Antagonists; D000975:Antioxidants; D002121:Calcium Channel Blockers; D018696:Neuroprotective Agents; D014665:Vasodilator Agents; D014810:Vitamin E; D024502:alpha-Tocopherol; D024505:Tocopherols; D010889:Piracetam
Sposobnost' piratsetama i tokoferola atsetata potentsirovat' klinicheskii effekt antianginal'nykh preparatov u bol'nykh ishemicheskoi bolezn'iu serdtsa (stabil'noi stenokardiei napriazheniia) v pozhilom i starcheskom vozraste.