title: [Clinical and morphologic features in patients with acute nephritis syndrome].
abstract: Acute glomerulonephritis is a distinct clinical entity, more frequently found in younger age. We report 69 patients with AcGN (25 female and 44 male) mean age 26 years (range 15-58). The disease is clinically characterized with hypertension (57%), edema (59%) and oliguria (35%). Urine analysis showed microhaematuria/proteinuria (36%) and micro/macrohaematuria alone in 89%, while azothaemia was observed in 16% pts, and decreased serum complement levels in one third of patients, more often decrease of C3 (33%) than C4 (15%). Initial infection of the upper respiratory tract was seen in 65%, pneumonia in 8%. In 25% of pts. there were no data of previous infection. Cultures of pharyngeal smear revealed. Streptococcus only in 2 pts. Elevated AST titer was found in 32% pts. Eleven kidney biopsies were made, and histological examination showed 2 normal findings, 6 mesangioproliferative GH, 2 endocapillary GN and 1 membranoproliferative GN. Follow ups have showed urinary abnormalities in 25% of pts., without developing renal failure.
authors.affiliation: Clinic of Nephrology and Clinical Immunology, Institute of Internal Diseases, Novi Sad.
authors.forename: I
authors.initials: I
authors.lastname: Mitić
authors.forename: D
authors.initials: D
authors.lastname: Fele
authors.forename: P
authors.initials: P
authors.lastname: Tepavcević
authors.forename: S
authors.initials: S
authors.lastname: Djurić
authors.forename: P
authors.initials: P
authors.lastname: Lenert
authors.forename: D
authors.initials: D
authors.lastname: Bozić
authors.forename: S
authors.initials: S
authors.lastname: Vodopivec
authors.forename: V
authors.initials: V
authors.lastname: Sakac
authors.forename: T
authors.initials: T
authors.lastname: Ilić
authors.forename: T
authors.initials: T
authors.lastname: Djurdjević-Mirković
authors.forename: L
authors.initials: L
authors.lastname: Sebić
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D005260:Female; D005921:Glomerulonephritis / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged
vernacular_title: Klinicke i morfoloske odlike bolesnika s akutnim nefritisnim sindromom.