Detection of cytokine expression in human palatine tonsils.
We investigated cytokine mRNA expression in human palatine tonsils from 20 patients. Expression of TNF-alpha mRNA was detected in 11 of 20 patients. IL- 1 alpha mRNA was detected in 2 patients and IL-2 mRNA in one patient. No expression of IL-4, IL-6 and interferon-gamma was detected in any of the 20 patients. TNF-alpha may play an important role in tonsillar diseases.
Tanaka
S
S
Department of Otorhinolaryngology, School of Medicine, Kanazawa University, Japan.
Nakagawa
S
S
Furukawa
M
M
D016207:Cytokines / Q000276:immunology*; D006801:Humans; D014066:Palatine Tonsil / Q000276:immunology*; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger; D014158:Transcription, Genetic; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology
D016207:Cytokines; D012333:RNA, Messenger; D014409:Tumor Necrosis Factor-alpha