title: [Incidence and clinical manifestations of hepatitis C virus infection in patients on hemodialysis].
abstract: Hepatitis C virus infection is a very important problem among patients on maintenance hemodialysis. To determine incidence and clinical manifestations of hepatitis C virus infection, we tested blood samples of patients on hemodialysis in 1992 and 1994 using ELISA a HCV test of second generation. In 1992 46 out of 119 patients (38%), and in 1994 36 out of 122 (29%) patients on hemodialysis were aHCV positive. Duration of dialysis program and level of serum aminotransferases were significantly higher in the group of aHCV positive patients had received more blood transfusions per year, but not significantly higher than HCV negative patients. These results with knowledge about common routes of HCV transmission, demand strict preventive measures in dialysis units, routine and regular HCV testing of patients' blood samples and serum aminotransferases level, and isolation of HCV positive patients and machines.
authors.affiliation: Clinic of Nephrology, Clinical Centre of Serbia, Belgrade.
authors.forename: M
authors.initials: M
authors.lastname: Radović
authors.forename: V
authors.initials: V
authors.lastname: Ostrić
authors.forename: M
authors.initials: M
authors.lastname: Korolija
authors.forename: Lj
authors.initials: Lj
authors.lastname: Djukanović
authors.forename: N
authors.initials: N
authors.lastname: Zakula
authors.forename: T
authors.initials: T
authors.lastname: Radulović
mesh_terms: D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006526:Hepatitis C / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D018937:Hepatitis C Antibodies / Q000032:analysis; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D065227:Transfusion Reaction
chemical_list: D018937:Hepatitis C Antibodies
vernacular_title: Ucestalost i klinicke pojave infekcije virusom hepatitisa C kod bolesnika na hemodijalizi.