Drug-induced movement disorders.
Parkinsonism, tremor, chorea-ballismus, dystonia, tardive dyskinesia, myoclonus, tics and akathisia can be induced by many drugs. The drugs that are most frequently implicated in movement disorders are antipsychotics, calcium antagonists, orthopramides and substituted benzamides (e.g. metoclopramide, sulpiride, clebopride, domperidone), CNS stimulants, antidepressants, anticonvulsants, antiparkinsonian drugs and lithium. It is possible for a single drug to induce 2 or more types of movement disorders in the same patient. Movement disorders are not always reversible after drug withdrawal.
Jiménez-Jiménez
F J
FJ
Department of Neurology, Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain.
García-Ruiz
P J
PJ
Molina
J A
JA
D017109:Akathisia, Drug-Induced / Q000503:physiopathology / Q000517:prevention & control; D000927:Anticonvulsants / Q000009:adverse effects; D014150:Antipsychotic Agents / Q000009:adverse effects*; D002121:Calcium Channel Blockers / Q000009:adverse effects*; D002819:Chorea / Q000139:chemically induced; D004409:Dyskinesia, Drug-Induced / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D006801:Humans; D010302:Parkinson Disease, Secondary / Q000139:chemically induced* / Q000517:prevention & control; D012307:Risk Factors; D014202:Tremor / Q000139:chemically induced
D000927:Anticonvulsants; D014150:Antipsychotic Agents; D002121:Calcium Channel Blockers