title: Effect of human milk prostaglandins and lactoferrin on respiratory syncytial virus and rotavirus.
abstract: The effect of lactoferrin and prostaglandins E and F2 alpha on the growth of rotavirus and respiratory syncytial virus in cell culture was investigated. Lactoferrin inhibited the growth of respiratory syncytial virus at a concentration tenfold lower than that normally present in human milk. The prostaglandins had no effect on either virus growth, even at a concentration of 100-fold more than that found in human milk. Lactoferrin may have some antiviral properties in human milk in addition to its known antibacterial functions.
authors.affiliation: School of Microbiology, Latrobe University, Bundoora, Victoria, Australia.
authors.forename: M
authors.initials: M
authors.lastname: Grover
authors.forename: O
authors.initials: O
authors.lastname: Giouzeppos
authors.forename: R D
authors.initials: RD
authors.lastname: Schnagl
authors.forename: J T
authors.initials: JT
authors.lastname: May
mesh_terms: D000818:Animals; D006801:Humans; D066298:In Vitro Techniques; D007781:Lactoferrin / Q000494:pharmacology*; D008892:Milk; D011453:Prostaglandins / Q000494:pharmacology*; D012136:Respiratory Syncytial Viruses / Q000187:drug effects*; D012401:Rotavirus / Q000187:drug effects*
chemical_list: D011453:Prostaglandins; D007781:Lactoferrin