title: A theoretical basis for the high-frequency performance of the outer hair cell's receptor potential.
abstract: The frequency response of the outer hair cell (OHC) was studied theoretically. An electrical model of the OHC was analyzed mathematically, taking into account the effect of its inherent voltage-dependent capacitance. It was found that the variations of the capacitance dependent on the membrane potential could enhance the high-frequency response of the OHC, so that its cutoff frequency could be extended into the audio range. It was found further that the enhancement of the frequency response of the OHC was strongly dependent on its resting potential and on the ratio of the maximum voltage-dependent capacitance to the membrane linear capacitance.
authors.affiliation: Arbeitsgruppe III (Biophysik), Institut für Zoologie, Johannes-Gutenberg-Universität, Mainz, Germany.
authors.lastname: Hassan el-S
mesh_terms: D006198:Hair Cells, Auditory / Q000502:physiology*; D006801:Humans; D008953:Models, Anatomic