title: Leukoencephalomalacia.
abstract: Leukoencephalomalacia in horses is caused by fumonisins. These mycotoxins are produced by Fusarium spp. that contaminate corn and corn byproducts while in the field. The most common clinical presentation is a multifocal neurologic disease that affects multiple horses in a herd. Although the majority of affected horses die, treatment directed at decreasing inflammation and edema in the CNS may result in recovery in some animals.
authors.affiliation: Triangle Research Consortium, Cary, North Carolina, USA.
authors.forename: C
authors.initials: C
authors.lastname: Uhlinger
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D004032:Diet / Q000592:standards / Q000662:veterinary; D004678:Encephalomalacia / Q000175:diagnosis / Q000209:etiology / Q000662:veterinary*; D005440:Fluid Therapy / Q000662:veterinary; D005670:Fusarium / Q000302:isolation & purification; D006734:Horse Diseases / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006736:Horses; D009657:North Carolina / Q000453:epidemiology; D003313:Zea mays / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents