title: Rational design of vaccines.
authors.affiliation: Chiron Vaccines, Siena, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Rappuoli
mesh_terms: D000907:Antibodies, Bacterial / Q000096:biosynthesis; D002675:Child, Preschool; D004305:Dose-Response Relationship, Drug; D017277:Drug Approval; D015195:Drug Design; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010567:Pertussis Vaccine / Q000276:immunology / Q000627:therapeutic use*; D015202:Protein Engineering; D014611:Vaccination; D014614:Vaccines, Synthetic / Q000276:immunology / Q000627:therapeutic use*; D010566:Virulence Factors, Bordetella / Q000235:genetics / Q000276:immunology / Q000633:toxicity; D014917:Whooping Cough / Q000517:prevention & control*
chemical_list: D000907:Antibodies, Bacterial; D010567:Pertussis Vaccine; D014614:Vaccines, Synthetic; D010566:Virulence Factors, Bordetella