title: Women's health initiative. Why now? What is it? What's new?
abstract: Studies collectively named the Women's Health Initiative (WHI) are currently enrolling 164,500 postmenopausal women in several overlapping clinical trials and an observational study. The overall goals of WHI are to understand the determinants of postmenopausal women's health and to evaluate the efficacy of practical interventions in preventing the major causes of morbidity and mortality in older women. This article reviews the research leading to the WHI studies; describes the study designs and protocols, with an emphasis on what's new about WHI from a psychological perspective; and outlines the major psychosocial hypotheses under investigation and the major challenges WHI presents to psychological science.
authors.affiliation: Department of Psychiatry, University of Pittsburgh, PA 15213, USA. karenmat@pop.pitt.edu
authors.forename: K A
authors.initials: KA
authors.lastname: Matthews
authors.forename: S A
authors.initials: SA
authors.lastname: Shumaker
authors.forename: D J
authors.initials: DJ
authors.lastname: Bowen
authors.forename: R D
authors.initials: RD
authors.lastname: Langer
authors.forename: J R
authors.initials: JR
authors.lastname: Hunt
authors.forename: R M
authors.initials: RM
authors.lastname: Kaplan
authors.forename: R C
authors.initials: RC
authors.lastname: Klesges
authors.forename: C
authors.initials: C
authors.lastname: Ritenbaugh
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000517:prevention & control / Q000523:psychology; D002979:Climacteric / Q000523:psychology*; D015179:Colorectal Neoplasms / Q000517:prevention & control / Q000523:psychology; D003327:Coronary Disease / Q000517:prevention & control / Q000523:psychology; D005260:Female; D005544:Forecasting; D015438:Health Behavior; D006293:Health Promotion / Q000639:trends; D006801:Humans; D008019:Life Style; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000517:prevention & control / Q000523:psychology; D016032:Randomized Controlled Trials as Topic; D014481:United States; D014932:Women's Health Services / Q000639:trends*