title: Soft-tissue uptake of technetium-99m-MDP after prostate cryoablation.
abstract: Prominent soft-tissue uptake of 99mTc-methylene diphosphonate (MDP) within the prostate bed was found after cryoablation for prostate carcinoma. CT, MRI and sonographic studies demonstrated liquifactive necrosis of the prostate bed. The probable etiology for 99mTc-MDP uptake in this case is necrosis with subsequent neovascular hyperemia and microscopic calcium deposits. Three-phase scintigraphy with 99mTc-MDP appears to be useful for localizing the extent of soft tissue inflammation and necrosis.
authors.affiliation: Department of Nuclear Medicine, Temple University Hospital, Philadelphia, Pennsylvania, USA.
authors.forename: I
authors.initials: I
authors.lastname: Zucker
authors.forename: N D
authors.initials: ND
authors.lastname: Charkes
authors.forename: E J
authors.initials: EJ
authors.lastname: Seidmon
authors.forename: A H
authors.initials: AH
authors.lastname: Maurer
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging; D003452:Cryosurgery / Q000009:adverse effects; D006801:Humans; D007249:Inflammation; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010388:Pelvis / Q000000981:diagnostic imaging* / Q000473:pathology; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D011877:Radionuclide Imaging; D013669:Technetium Tc 99m Medronate; D014057:Tomography, X-Ray Computed
chemical_list: D013669:Technetium Tc 99m Medronate