title: A neutron image plate quasi-Laue diffractometer for protein crystallography.
abstract: An instrument which is based on image plate technology has been constructed to perform cold neutron Laue crystallography on protein structures. The crystal is mounted at the center of a cylindrical detector which is 400mm long and has a circumference of 1000mm, with gadolinium oxide-containing image plates mounted on its exterior surface. Laue images registered on the plate are read out by rotating the drum and translating a laser read head parallel to the cylinder axis, giving a pixel size of 200 microm x 200 microm and a total read time of 5 minutes. Preliminary results indicate that it should be possible to obtain a complete data set from a protein crystal to atomic resolution in about two weeks.
authors.affiliation: European Molecular Biology Laboratory, Grenoble, France.
authors.forename: F
authors.initials: F
authors.lastname: Cipriani
authors.forename: J C
authors.initials: JC
authors.lastname: Castagna
authors.forename: C
authors.initials: C
authors.lastname: Wilkinson
authors.forename: M S
authors.initials: MS
authors.lastname: Lehmann
authors.forename: G
authors.initials: G
authors.lastname: Büldt
mesh_terms: D000818:Animals; D002645:Chickens; D003461:Crystallography / Q000295:instrumentation* / Q000379:methods; D018360:Crystallography, X-Ray; D004867:Equipment Design; D009113:Muramidase / Q000737:chemistry; D009502:Neutrons; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*
chemical_list: D011506:Proteins; D009113:Muramidase