Endometrial involvement by multiple myeloma.
We report a case of a 79-year-old woman with known multiple myeloma who had a serum immunoglobulin G-kappa paraprotein and kappa light chain Bence-Jones proteinuria. Abnormal uterine bleeding prompted an endometrial biopsy, the results of which showed an extensive infiltration of the endometrial stroma by large, atypical cells, which were further characterized as neoplastic plasma cells. Multiple myeloma can rarely involve the endometrium and can be a cause of abnormal uterine bleeding.
Smith
N L
NL
Department of Pathology and Laboratory Medicine, East Carolina University, School of Medicine, Greenville, North Carolina, USA.
Baird
D B
DB
Strausbauch
P H
PH
D000368:Aged; D001706:Biopsy; D002466:Cell Nucleolus / Q000473:pathology; D002467:Cell Nucleus / Q000473:pathology; D016889:Endometrial Neoplasms / Q000150:complications / Q000473:pathology*; D004717:Endometrium / Q000473:pathology; D005260:Female; D006801:Humans; D009101:Multiple Myeloma / Q000473:pathology*; D010950:Plasma Cells / Q000473:pathology; D014592:Uterine Hemorrhage / Q000209:etiology