A nongenetic basis of cycle frequency in bipolar disorder: study of a monozygotic twin pair.
The authors describe a pair of monozygotic twins with bipolar disorder but with a different course of the illness including age of onset, sequence of episodes, and cycle length. Based on these findings, the clinical course of bipolar illness does not appear to be genetically determined.
Sharma
V
V
Mood Disorders Unit, London Psychiatric Hospital, Ontario, Canada.
Ainsworth
P J
PJ
McCabe
S B
SB
Persad
E
E
Kueneman
K M
KM
D000328:Adult; D000928:Antidepressive Agents / Q000008:administration & dosage / Q000009:adverse effects; D001714:Bipolar Disorder / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics* / Q000523:psychology; D004200:Diseases in Twins / Q000235:genetics* / Q000523:psychology; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D016651:Lithium Carbonate / Q000008:administration & dosage / Q000009:adverse effects; D012008:Recurrence; D014430:Twins, Monozygotic / Q000235:genetics / Q000523:psychology
D000928:Antidepressive Agents; D016651:Lithium Carbonate