title: [The biological effect of fireproof ceramic fibers--literature review].
abstract: The work presents reports, selected from the world literature, on the studies of biological effect of refractory ceramic fibres, carried out on experimental animals. The discrepancy between the results of studies performed may originate from differences in the distribution of fibre sizes or the durability of fibres in the organism and their surface properties which, in turn, depend on the chemical composition of fibres. In all studies discussed, ceramic fibres generally activated macrophages and they were characterised by a moderate fibrotic activity. A statistically significant increase in the incidence of tumor (mesothelioma) observed in several very important experimental studies may suggest that some types of refractory ceramic fibres show a similar carcinogenic potential to that of natural asbestos: crocidolite or chrysotile.
authors.affiliation: Zakładu Aerozoli, Instytutu Medycyny Pracy, Lodzi.
authors.forename: A
authors.initials: A
authors.lastname: Krajnow
mesh_terms: D000818:Animals; D002516:Ceramics / Q000633:toxicity*; D005411:Flame Retardants / Q000009:adverse effects; D008262:Macrophage Activation; D008297:Male; D008654:Mesothelioma / Q000209:etiology*; D019016:Mineral Fibers / Q000009:adverse effects*; D010316:Particle Size
chemical_list: D005411:Flame Retardants; D019016:Mineral Fibers
vernacular_title: Działanie biologiczne ogniotrwałych włókien ceramicznych--przeglad piśmiennictwa.