title: Thermoregulatory vasoconstriction does not impede core warming during cutaneous heating.
abstract: Recent studies evaluating perioperative cutaneous-to-core heat transfer indicate that: Thermoregulatory vasoconstriction prevents further core cooling in anesthetized subjects during mild cooling. Thermoregulatory vasoconstriction only slightly decreases core cooling rates in anesthetized subjects during vigorous cooling. Thermoregulatory vasoconstriction does not impair vigorous core rewarming during anesthesia. Vigorous postanesthetic cutaneous warming increases core temperature much faster than passive insulation. Under conditions of mild thermal stress, thermoregulatory vasoconstriction is thus able to protect core temperature by reducing cutaneous heat transfer and functionally isolating the peripheral and core thermal compartment. Consequently, anesthetic-induced alterations in vasomotor tone is one of the major factors influencing core temperature in patients who are not actively cooled or warmed. In contrast, thermoregulatory tone is insufficient to prevent core temperature perturbations in patients undergoing vigorous cutaneous cooling or warming.
authors.affiliation: Department of Anesthesia, University of California, San Francisco 94143-0648, USA.
authors.forename: R
authors.initials: R
authors.lastname: Christensen
authors.forename: D
authors.initials: D
authors.lastname: Clough
authors.forename: A
authors.initials: A
authors.lastname: Kurz
authors.forename: O
authors.initials: O
authors.lastname: Plattner
authors.forename: D I
authors.initials: DI
authors.lastname: Sessler
authors.forename: J
authors.initials: J
authors.lastname: Xiong
mesh_terms: D001833:Body Temperature Regulation; D006801:Humans; D007530:Isoflurane / Q000494:pharmacology*; D008297:Male; D010101:Oxygen Consumption / Q000187:drug effects; D015742:Propofol / Q000494:pharmacology*; D012039:Regional Blood Flow; D012867:Skin / Q000098:blood supply*; D012879:Skin Physiological Phenomena; D013514:Surgical Procedures, Operative; D013997:Time Factors; D014661:Vasoconstriction / Q000187:drug effects*
chemical_list: D007530:Isoflurane; D015742:Propofol