Expression of somatostatin in neurons of the central posterior/prepacemaker nucleus projecting to the preglomerular nucleus: immunohistochemical evidence for a non-synaptic function.
In the diencephalon of the weakly electric gymnotiform fish Apteronous leptorhynchus, part of the central posterior/prepacemaker nucleus innervates the preglomerular nucleus. A minor population of these neurons expresses immunoreactivity against somatostatin, as has been shown by combining peptide immunohistochemistry with an in vitro tract-tracing technique. In contrast to the expectation, however, this neuropeptide does not appear to be transported along the axons to the projection site, as somatostatin-like immunoreactivity could not be detected in the preglomerular nucleus. It is, therefore, likely that somatostatin expressed in these neurons exerts a non-synaptic function in the region of the central posterior/prepacemaker nucleus itself.
Zupanc
G K
GK
Abteilung Physikalische Biologie, Max-Planck-Institut für Entwicklungsbiologie, Tübingen, Germany. zupanc@mpib-tuebingen.mpg.de
Horschke
I
I
Stroh
T
T
D000818:Animals; D001683:Biological Clocks / Q000502:physiology*; D001923:Brain Chemistry / Q000502:physiology; D004027:Diencephalon / Q000737:chemistry / Q000166:cytology* / Q000502:physiology; D005399:Fishes; D007150:Immunohistochemistry; D008239:Lysine / Q000031:analogs & derivatives; D009474:Neurons / Q000737:chemistry* / Q000502:physiology; D013004:Somatostatin / Q000032:analysis*; D013569:Synapses / Q000502:physiology
D013004:Somatostatin; C013411:biocytin; D008239:Lysine