Characterization of monoclonal antibodies in section 2B using enzymes and variant red blood cells.
Antibodies in Section 2B of the Third International Workshop on Monoclonal Antibodies were tested against human erythrocytes treated with different enzymes and against erythrocytes with well-defined rare phenotypes by immunoblotting and hemagglutination. In some instances, the epitope recognized by the Mab was precisely determined.
Reid
M E
ME
Immunochemistry Laboratory, New York Blood Center, New York 10021, USA.
Halverson
G R
GR
D001457:Anion Exchange Protein 1, Erythrocyte / Q000235:genetics / Q000276:immunology*; D000911:Antibodies, Monoclonal; D000918:Antibody Specificity; D004798:Enzymes; D018604:Epitope Mapping; D004912:Erythrocytes / Q000276:immunology*; D014644:Genetic Variation; D006021:Glycophorins / Q000235:genetics / Q000276:immunology*; D006386:Hemagglutination Tests; D006801:Humans; D015151:Immunoblotting; D011110:Polymorphism, Genetic
D001457:Anion Exchange Protein 1, Erythrocyte; D000911:Antibodies, Monoclonal; D004798:Enzymes; D006021:Glycophorins