title: Does electrothrombosis occur immediately after embolization of an aneurysm with Guglielmi detachable coils?
abstract: Current options for treating cerebral aneurysms include surgical clipping and placement of Guglielmi detachable coils (GDCs). The latter system is reported to induce acute aneurysmal occlusion by a mechanism of electrothrombosis. We report our observations in the case of a ruptured aneurysm treated with GDCs and then surgically exposed 2 hours later. The lack of thrombus within the aneurysm and around the coils led us to question the mechanism of action of GDCs.
authors.affiliation: Department of Neurosurgery, University of Texas Southwestern Medical Center at Dallas 75235, USA.
authors.forename: M
authors.initials: M
authors.lastname: Horowitz
authors.forename: D
authors.initials: D
authors.lastname: Samson
authors.forename: P
authors.initials: P
authors.lastname: Purdy
mesh_terms: D017542:Aneurysm, Ruptured / Q000000981:diagnostic imaging / Q000628:therapy*; D002533:Cerebral Angiography; D002544:Cerebral Infarction / Q000000981:diagnostic imaging; D003399:Craniotomy; D004621:Embolization, Therapeutic / Q000295:instrumentation*; D004867:Equipment Design; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D012008:Recurrence; D019233:Retreatment; D013345:Subarachnoid Hemorrhage / Q000000981:diagnostic imaging / Q000628:therapy*; D014057:Tomography, X-Ray Computed; D017211:Treatment Failure