Simultaneous pharmacokinetic screening of a mixture of compounds in the dog using API LC/MS/MS analysis for increased throughput.
Berman
J
J
Glaxo Wellcome, Research Triangle Park, North Carolina 27709, USA. berman-j@glaxo.com
Halm
K
K
Adkison
K
K
Shaffer
J
J
D000317:Adrenergic alpha-Antagonists / Q000097:blood / Q000737:chemistry / Q000493:pharmacokinetics*; D000818:Animals; D002853:Chromatography, Liquid; D004285:Dogs; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D013058:Mass Spectrometry; D015394:Molecular Structure; D013329:Structure-Activity Relationship
D000317:Adrenergic alpha-Antagonists