Olfactory threshold after nasal allergen challenge.
Olfactory threshold was investigated in patients with verified allergic rhinitis to birch pollen. In 20 patients the olfactory threshold was measured before and after challenge with topically applied birch pollen allergen during a non-symptomatic period. After provocation a statistically significant impaired detection sensitivity was found. The change in olfactory threshold was correlated with the measured amount of nasal secretions but not with subjectively or objectively registered nasal obstruction. A pronounced allergic reaction after allergen challenge is accompanied by an elevated olfactory threshold.
Hinriksdóttir
I
I
Department of Otorhinolaryngology, Central Hospital, Skövde, Sweden.
Murphy
C
C
Bende
M
M
D020001:1-Butanol; D000281:Administration, Intranasal; D000293:Adolescent; D000328:Adult; D000485:Allergens; D000440:Butanols / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000378:metabolism; D015508:Nasal Obstruction / Q000503:physiopathology; D009299:Nasal Provocation Tests; D009666:Nose / Q000473:pathology / Q000503:physiopathology; D009812:Odorants; D011058:Pollen; D006255:Rhinitis, Allergic, Seasonal / Q000473:pathology / Q000503:physiopathology*; D012684:Sensory Thresholds / Q000502:physiology*; D012903:Smell / Q000502:physiology*; D014197:Trees
D000485:Allergens; D000440:Butanols; D020001:1-Butanol