Cohort studies and randomized controlled studies in endocrinology.
This article describes the basic skills for the design, implementation, and interpretation of randomized controlled studies. Strengths and limitations of each study design are discussed. Epidemiologic issues in the analysis and interpretation of studies, such as loss to follow-up and biases, are included. Numerous clinical examples are provided to better illustrate the epidemiologic methodology.
Salamone
L M
LM
Graduate School of Public Health, University of Pittsburgh, Pennsylvania, USA.
Cauley
J A
JA
D015331:Cohort Studies; D004700:Endocrine System Diseases; D004704:Endocrinology; D006801:Humans; D015588:Observer Variation; D016032:Randomized Controlled Trials as Topic / Q000379:methods