Effect of heat stress on muscle sympathetic nerve activity in humans.
To elucidate the effect of heat stress on the sympathetic nervous system, we evaluated changes in muscle sympathetic nerve activity (MSNA), plasma arginine vasopressin (AVP), tympanic temperature, skin blood flow, cardiac output, mean blood pressure, and heart rate in 9 subjects in response to acute heat stress induced by raising the ambient temperature from 29 to 34 degrees C and then to 40 degrees C. With the heat exposure, MSNA was significantly increased with a significant increase in tympanic temperature. Skin blood flow and heart rate were also significantly increased, while mean blood pressure tended to decline and cardiac output tended to increase. The combination of the increased MSNA and skin blood flow may have caused the redistribution of the circulatory blood volume from the muscles to the skin, facilitating convection heat loss. The increases in MSNA counteracted the lowered blood pressure during heat exposure. Thus, the increased MSNA may play an important role both in thermoregulation and in the maintenance of blood pressure against heat stress.
Niimi
Y
Y
Department of Autonomic Neuroscience, Nagoya University, Japan.
Matsukawa
T
T
Sugiyama
Y
Y
Shamsuzzaman
A S
AS
Ito
H
H
Sobue
G
G
Mano
T
T
D000328:Adult; D001127:Arginine Vasopressin / Q000097:blood; D001794:Blood Pressure; D001833:Body Temperature Regulation / Q000502:physiology*; D002302:Cardiac Output; D004432:Ear, Middle / Q000098:blood supply; D005260:Female; D006339:Heart Rate; D006439:Hemodynamics; D006358:Hot Temperature; D006801:Humans; D008297:Male; D018482:Muscle, Skeletal / Q000098:blood supply / Q000294:innervation*; D009638:Norepinephrine / Q000097:blood; D012867:Skin / Q000098:blood supply; D012881:Skin Temperature / Q000502:physiology; D013312:Stress, Physiological / Q000097:blood / Q000503:physiopathology*; D013564:Sympathetic Nervous System / Q000503:physiopathology*; D013979:Tibial Nerve / Q000503:physiopathology; D014065:Tonometry, Ocular
D001127:Arginine Vasopressin; D009638:Norepinephrine