title: Clinical and laboratory radiographic caries diagnosis. A study of the same teeth.
abstract: OBJECTIVE
  To compare the diagnostic accuracy of radiographs obtained both in vivo and in vitro of the same teeth for the detection of occlusal and approximal caries.
  
  
  METHODS
  Pre- and post-extraction radiographs were obtained of 130 teeth, mostly third molars. The two sets of radiographs were assessed by four independent observers using a five-level confidence scale. Caries was validated histologically after serial sectioning. A positive diagnosis was defined as caries present in dentine occlusally and in enamel or deeper approximally. The diagnostic accuracy was expressed by ROC curve areas.
  
  
  RESULTS
  For occlusal caries, the average ROC curve area was 0.767 in the in vivo and 0.826 in the in vitro radiographs. The corresponding areas for approximal caries were 0.707 and 0.735, respectively. The differences were not significant (p > 0.05).
  
  
  CONCLUSIONS
  The outcome of radiographic caries diagnosis in the clinic appeared comparable with that obtained in the laboratory.
authors.affiliation: Department of Oral Radiology, Faculty of Health Sciences, University of Aarhus, Denmark.
authors.forename: H
authors.initials: H
authors.lastname: Hintze
authors.forename: A
authors.initials: A
authors.lastname: Wenze
mesh_terms: D003731:Dental Caries / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008964:Molar, Third / Q000000981:diagnostic imaging / Q000473:pathology; D015588:Observer Variation; D012372:ROC Curve; D011861:Radiography, Dental / Q000379:methods; D015203:Reproducibility of Results