title: Acute acalculous cholecystitis with a decrease in CD4/CD8 ratio.
abstract: Acute acalculous cholecystitis (AAC) usually occurs in the elderly and in those with severe pre-existing pathological conditions. However, there have recently been reports of AAC in relatively young immunosuppressed patients, such as those with acquired immunodeficiency syndrome (AIDS). We report here a 27-year-old woman with AAC who received an emergent cholecystectomy. Although anti-human immunodeficiency virus antibody (anti-HIV) was not detected, a decrease in the CD4/CD8 ratio in sera was found. This rare case of AAC in a patient with decreased CD4/CD8 ratio who showed no other related diseases suggests that surgeons should keep in mind the possible presence of immunosuppression in this condition.
authors.affiliation: First Department of Surgery, University of Tokyo, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Ikeda
authors.forename: W
authors.initials: W
authors.lastname: Kimura
authors.forename: N
authors.initials: N
authors.lastname: Futakawa
authors.forename: Y
authors.initials: Y
authors.lastname: Komuro
authors.forename: M
authors.initials: M
authors.lastname: Ono
authors.forename: B
authors.initials: B
authors.lastname: Zhao
authors.forename: T
authors.initials: T
authors.lastname: Muto
mesh_terms: D000208:Acute Disease; D000328:Adult; D016516:CD4-CD8 Ratio; D002764:Cholecystitis / Q000175:diagnosis / Q000276:immunology*; D005260:Female; D006801:Humans; D016867:Immunocompromised Host