Stevens-Johnson syndrome associated with methazolamide treatment reported in two Japanese-American women.
BACKGROUND
Systemic acetazolamide treatment has been reported in association with Stevens-Johnson syndrome (SJS). This is the first report of this syndrome associated with methazolamide treatment. The association is reported in two Japanese-American women.


RESULTS
Two patients with SJS, which developed during treatment with methazolamide, are described. Other potential associations are discussed.


CONCLUSIONS
Systemically administered carbonic anhydrase inhibitors, including both acetazolamide and methazolamide can be associated with SJS.
Flach
A J
AJ
University of California, San Francisco Medical Center, Department of Ophthalmology, Corte Madera 94976, USA.
Smith
R E
RE
Fraunfelder
F T
FT
D000328:Adult; D000368:Aged; D002257:Carbonic Anhydrase Inhibitors / Q000009:adverse effects*; D005128:Eye Diseases / Q000139:chemically induced* / Q000208:ethnology / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007564:Japan / Q000208:ethnology; D008704:Methazolamide / Q000009:adverse effects*; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced* / Q000208:ethnology / Q000473:pathology; D014481:United States / Q000453:epidemiology
D002257:Carbonic Anhydrase Inhibitors; D008704:Methazolamide