[Comparative study of methods for determining antibodies to measles virus].
The authors have developed enzyme immunoassay (EIA) for detecting antimeasles antibodies in the serum and compared it to routine methods. Preparation and purification of measles virus antigen used in EIA and optimal conditions of the reaction are described. Results of the routine methods and those of EIA correlated. EIA was used to determine titers of antimeasles antibodies in the sera of vaccinated children. 3-4 years after the vaccination the antibodies were undetectable in the sera of 23% of children.
Agafonov
A P
AP
Nicheukhina
S N
SN
Merzlikin
N V
NV
Kolmakova
E A
EA
Goncharov
A M
AM
Popov
V F
VF
Maĭdaniuk
A G
AG
Agnat'ev
G M
GM
D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis*; D002675:Child, Preschool; D002522:Chlorocebus aethiops; D006168:Guinea Pigs; D006801:Humans; D007124:Immunoenzyme Techniques; D008459:Measles virus / Q000276:immunology* / Q000648:ultrastructure; D008722:Methods; D008854:Microscopy, Electron; D011817:Rabbits; D014709:Vero Cells
D000914:Antibodies, Viral
Sravnitel'noe izuchenie metodov opredeleniia antitel k virusu kori.