Septo-optic dysplasia associated with cerebral cortical dysplasia (cortico-septo-optic dysplasia).
It is generally accepted that there are two subsets of septo-optic dysplasia (deMorsier's syndrome), one with schizencephaly and the other without schizencephaly. A third form of the anomaly which is associated with callosal absence has also been described. Except for schizencephaly, the association of septo-optic dysplasia with another major type of disorder of neuronal migration and organization such as cortical dysplasia, has not yet been reported. We report the MR imaging examination of a 3-year-old patient with bilateral rolandic cortical dysplasia, and with apparent thinning of the optic nerves, and absent septum pellucidum (septo-optic dysplasia) as a new combination. This can be labelled as cortico-septo-optic dysplasia.
Sener
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RN
Department of Radiology, Ege University Hospital, Bornova, Izmir, Turkey.
D061085:Agenesis of Corpus Callosum; D002675:Child, Preschool; D005260:Female; D005625:Frontal Lobe / Q000002:abnormalities*; D006801:Humans; D017436:Kallmann Syndrome / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D009900:Optic Nerve / Q000002:abnormalities*; D012688:Septum Pellucidum / Q000002:abnormalities*