title: Single cell analyses of cytokine production.
abstract: Subsets of T lymphocytes have been defined by their secretion of polarized patterns of cytokines. Type 1 and Type 2 subsets have been characterized in a variety of model systems both in vivo and in vitro and are a useful framework for studying immune responses. Recent technical advances have made it possible to analyze cytokine production by these populations at the level of individual cells.
authors.affiliation: Trudeau Institute, New York, NY 12983, USA.
authors.forename: L L
authors.initials: LL
authors.lastname: Carter
authors.forename: S L
authors.initials: SL
authors.lastname: Swain
mesh_terms: D016207:Cytokines / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D017403:In Situ Hybridization; D016133:Polymerase Chain Reaction; D013601:T-Lymphocytes / Q000166:cytology* / Q000276:immunology / Q000378:metabolism*; D018417:Th1 Cells / Q000378:metabolism; D018418:Th2 Cells / Q000378:metabolism
chemical_list: D016207:Cytokines