title: A histologic evaluation of localized ridge augmentation utilizing DFDBA in combination with e-PTFE membranes and stainless steel bone pins in humans.
abstract: This study evaluated histologically and clinically the use of decalcified freeze-dried bone allograft in conjunction with Gore-Tex Augmentation Material and Memfix bone pins for localized ridge augmentation in three cases. Biopsies taken at 3, 6, and 9 months were evaluated. It was concluded that: (1) guided bone regeneration may be performed at local immediate extraction sites when flap design permits primary wound closure; (2) decalcified freeze-dried bone allografts used in conjunction with supporting pins may contribute to successful bone regeneration either by osseoinduction or osseoconduction, and/or by maintaining the membrane-created space during the early events in wound healing; and (3) at 9 months, guided bone regeneration utilizing Gore-Tex Augmentation Material membranes and decalcified freeze-dried bone allografts resulted in the formation of dense, viable new bone.
authors.affiliation: Department of Periodontology, Temple University School of Dentistry, Philadelphia, Pennsylvania 19140, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Doblin
authors.forename: L M
authors.initials: LM
authors.lastname: Salkin
authors.forename: J R
authors.initials: JR
authors.lastname: Mellado
authors.forename: A L
authors.initials: AL
authors.lastname: Freedman
authors.forename: M D
authors.initials: MD
authors.lastname: Stein
mesh_terms: D000328:Adult; D016301:Alveolar Bone Loss / Q000601:surgery*; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D001858:Bone Nails; D001861:Bone Regeneration; D016025:Bone Transplantation; D005612:Freeze Drying; D016557:Guided Tissue Regeneration, Periodontal; D006801:Humans; D008297:Male; D008437:Maxilla; D008567:Membranes, Artificial; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D013524:Surgical Flaps
chemical_list: D008567:Membranes, Artificial; D011138:Polytetrafluoroethylene