title: Electroclinical study of localization-related epilepsies in early infancy.
abstract: To clarify the characteristics of localization-related epilepsies in early infancy, we performed an electroclinical study of 28 epileptic patients whose first seizures occurred before 6 months of age. The patients were retrospectively divided into two groups: the seizure-controlled group (8 patients) and the refractory group (20 patients). The seizure-controlled group included the patients whose seizures were suppressed within 1 year after onset; the refractory group included all other patients. The characteristics of the refractory group were as follows: (1) most patients had serious underlying pathologies; (2) the seizure type in most cases was simple partial seizure or complex partial seizure without secondary generalization; (3) the interictal EEG showed focal abnormalities and severe dysrhythmia on the basic pattern associated with multifocal spikes in most cases; and (4) in some patients, West syndrome developed after localization-related epilepsies and generalized seizures appeared later in some cases.
authors.affiliation: Department of Child Neurology, Okayama University Medical School, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Ohmori
authors.forename: Y
authors.initials: Y
authors.lastname: Ohtsuka
authors.forename: E
authors.initials: E
authors.lastname: Oka
authors.forename: T
authors.initials: T
authors.lastname: Akiyama
authors.forename: S
authors.initials: S
authors.lastname: Ohtahara
mesh_terms: D017668:Age of Onset; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000145:classification / Q000503:physiopathology*; D017029:Epilepsy, Complex Partial / Q000145:classification / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008991:Monitoring, Physiologic; D011379:Prognosis; D012189:Retrospective Studies; D017678:Sex Distribution