[Clinical features of HGBV-C-related liver cancer].
Recently, one of non-A to E hepatitis viruses was identified and the new virus was named HGV/GBV-C(HGBV-C). In Japan, more than 90% of liver cirrhosis and hepatocellular carcinoma were associated with hepatitis B or C virus infection. Proportion of HGBV-C infection was only 3.4% of patients with non-A to E chronic liver disease we examined. Thus, HGBV-C was considered to play only a minor role in chronic liver disease of unknown etiology. HGBV-C positive cases have a history of blood transfusion and/or operation and/or drug self-injection, and frequently co-infected with hepatitis C virus. Whether HGBV-C infection really causes severe chronic liver disease is required to be elucidated.
Kanda
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First Department of Medicine, Chiba University School of Medicine.
Yokosuka
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O
D000368:Aged; D015415:Biomarkers / Q000097:blood; D005260:Female; D018067:Flaviviridae / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008103:Liver Cirrhosis / Q000821:virology*; D008113:Liver Neoplasms / Q000821:virology*; D008297:Male; D008875:Middle Aged; D012367:RNA, Viral / Q000097:blood
D015415:Biomarkers; D012367:RNA, Viral