title: Salt depletion and dehydration in hypertensive preterm infants.
abstract: Three preterm infants presented with both severe or moderate arterial hypertension and dehydration due to increased water and sodium urinary excretion. In patient 1, water and sodium wasting were extremely severe and peaked at 575 ml/kg per day and 73 mEq/kg per day, respectively. In all infants, urinary water and sodium excretion dramatically decreased when hypertension resolved. The overall clinical data suggest a pressure natriuresis phenomenon.
authors.affiliation: Service de Pédiatrie 2, Hôpital d'Enfants, Dijon, France.
authors.forename: J B
authors.initials: JB
authors.lastname: Gouyon
authors.forename: S
authors.initials: S
authors.lastname: Bernardini
authors.forename: D S
authors.initials: DS
authors.lastname: Semama
authors.forename: M
authors.initials: M
authors.lastname: Françoise
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D001794:Blood Pressure / Q000502:physiology; D001798:Blood Proteins / Q000378:metabolism; D003681:Dehydration / Q000209:etiology / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000151:congenital / Q000378:metabolism; D007010:Hyponatremia / Q000209:etiology / Q000378:metabolism*; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000378:metabolism* / Q000652:urine; D008297:Male
chemical_list: D000959:Antihypertensive Agents; D001798:Blood Proteins