title: Fortuitous diagnosis of the association of hemoglobin J-Broussais with beta + thalassemia.
abstract: The authors report a case, not described so far in literature, of an association of HbJ-Broussais [alpha (90 (PG2) lys-->asn beta 2] with beta + thalassemia in a young girl born of Italian father and Breton mother. This association is clinically silent. Biochemistry revealed, besides HbA, the presence of HbJ-Broussais in the proportion of 19.4% and HbA2 value of 3.9%. These percentages, slightly lower than expected, are explained. A familial study is presented.
authors.affiliation: Laboratoire de biochimie, Centre Hospitalier et Universitaire, Hôpital Sud, Rennes, France.
authors.forename: M R
authors.initials: MR
authors.lastname: Durou
authors.forename: A
authors.initials: A
authors.lastname: Ribault
authors.forename: M J
authors.initials: MJ
authors.lastname: Dufour
authors.forename: G
authors.initials: G
authors.lastname: Gallou
authors.forename: A
authors.initials: A
authors.lastname: Ruelland
authors.forename: E
authors.initials: E
authors.lastname: Le Gall
authors.forename: L
authors.initials: L
authors.lastname: Cloarec
authors.forename: B
authors.initials: B
authors.lastname: Legras
mesh_terms: D002648:Child; D005260:Female; D006448:Hemoglobin J / Q000235:genetics*; D006801:Humans; D010375:Pedigree; D017086:beta-Thalassemia / Q000235:genetics*
chemical_list: D006448:Hemoglobin J