Cardiomyopathy: a late complication of hemolytic uremic syndrome.
This report describes a child who presented with classic hemolytic uremic syndrome (HUS) and 4 months later developed a life-threatening but reversible cardiomyopathy with global cardiac dysfunction and a left ventricular ejection fraction of 14%. There was no evidence of electrolyte abnormalities, anemia, hypertension, severe fluid overload, or viral infection. Endomyocardial biopsies were consistent with a dilated cardiomyopathy. This paper highlights the importance of considering the diagnosis of associated cardiomyopathy when presenting with late-onset edema following HUS.
Walker
A M
AM
Department of Pediatrics, Hospital for Sick Children, Toronto, Ontario, Canada.
Benson
L N
LN
Wilson
G J
GJ
Arbus
G S
GS
D009202:Cardiomyopathies / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D002316:Cardiotonic Agents / Q000627:therapeutic use; D002675:Child, Preschool; D005260:Female; D006333:Heart Failure / Q000188:drug therapy / Q000209:etiology / Q000473:pathology; D006463:Hemolytic-Uremic Syndrome / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D008854:Microscopy, Electron; D009206:Myocardium / Q000473:pathology; D014057:Tomography, X-Ray Computed
D002316:Cardiotonic Agents