[The regeneration of skeletal muscle tissue after a gunshot injury].
Peculiarities of skeletal muscular tissue regeneration were studied after inflicting the gunshot damage in rabbits. Phase 1 of the wound process consists of forming of the posttraumatic necrosis zone, disintegration of skeletal muscular tissue differons and macrophage activation. Proliferation phase starts 36 hrs after the wound was inflicted and includes myosatellitocyte activation and proliferation and myoblast appearance. The process of myogenic cell differentiation is similar to whose in embryonal myogenesis. Two ways of symplast appearance were described--the myoblastic one and the one by means of muscular bud growth from the viable muscular fiber. Regenerative and degenerative processes run simultaneously in all experiments studied. Definitive fibres located on a distance from the wound die so as the newly formed ones (sources of the delayed necrosis nidi). Results obtained allow to define the peculiarities of skeletal muscular tissue more precisely.
Danilov
R K
RK
Odintsova
I A
IA
Naĭdenova
Iu G
IuG
D000818:Animals; D003592:Cytophotometry; D004247:DNA / Q000096:biosynthesis; D006614:Hindlimb; D006651:Histocytochemistry; D008854:Microscopy, Electron; D018482:Muscle, Skeletal / Q000293:injuries* / Q000502:physiology* / Q000648:ultrastructure; D011817:Rabbits; D012038:Regeneration; D013053:Spectrophotometry; D013997:Time Factors; D014948:Wounds, Gunshot / Q000473:pathology / Q000503:physiopathology*
D004247:DNA
Regeneratsiia skeletnoĭ myshechnoĭ tkani posle ognestrel'nogo povrezhdeniia.