Bilateral non-Hodgkin's lymphoma of the breast mimicking mastitis.
We recently encountered a case of recurrent non-Hodgkin's lymphoma manifested after a long period of quiescence as bilateral involvement of the breasts. This 37-year-old woman had stage IVA nodular poorly differentiated lymphocytic lymphoma diagnosed 9 years previously and was followed up without treatment. She was lost to follow-up after 4 years but had been in good health until seen with malaise and fever and pain, swelling, and erythema involving both breasts. Biopsies of lymph node and bone marrow showed a high-grade non-Hodgkin's lymphoma (lymphoblastic lymphoma) of B cell origin with central nervous system involvement. Combination chemotherapy produced a dramatic remission, but the patient died of Pseudomonas septicemia.
Dawn
B
B
Department of Internal Medicine, University of Missouri-Columbia/Ellis Fischel Cancer Center 65203, USA.
Perry
M C
MC
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D016470:Bacteremia; D019046:Bone Marrow Neoplasms / Q000175:diagnosis; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000188:drug therapy; D016543:Central Nervous System Neoplasms / Q000175:diagnosis; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000188:drug therapy; D008228:Lymphoma, Non-Hodgkin / Q000175:diagnosis; D008413:Mastitis / Q000175:diagnosis*; D009364:Neoplasm Recurrence, Local; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000188:drug therapy; D011552:Pseudomonas Infections; D012074:Remission Induction