Resin-modified glass ionomer cements: fluoride release and influence on Streptococcus mutans growth.
The aims of the present study were to measure the fluoride release of 1 glass ionomer cement, 1 cermet, 3 resin-modified glass ionomer cements and 1 compomer, and to determine the influence of each material on bacterial growth. Test specimens were eluted in saline for 180 days. Every 2 days, the specimens were transferred into fresh saline and the fluoride content of the solution was measured. Furthermore, 48-h, 14-d, 90-d, and 180-d eluates were inoculated with Streptococcus mutans and bacterial growth was recorded nephelometrically. Fluoride release dropped significantly over time for each material with values between 6.2 (Ketac-Silver) and 29.3 (Photac-Fil) ppm after 48 h to values between 0.6 (Ketac-Silver) and 1.7 (Ketac-Fil, Vitremer) ppm after 180 days. Each material reduced bacterial growth at each time of examination, but the effect decreased significantly over time with a maximum growth of 71.7% (Ketac-Fil) to 85.6% (Ketac-Silver) after 48 h and 94.7 (Vitremer) to 99.0% (Ketac-Silver) after 180 days (growth control = 100%). Both Ketac-Silver and Dyract showed a significantly lower inhibiting effect on bacterial growth than the other materials. The tested materials showed a good correlation between fluoride release and influence on bacterial growth. However, both effects dropped dramatically over the 180-days period.
Friedl
K H
KH
Department of Operative Dentistry and Periodontology, University Clinics, Regensburg, Germany. Karl-heinz.Friedl@klinik.uni-regensburg.de
Schmalz
G
G
Hiller
K A
KA
Shams
M
M
D002327:Cariostatic Agents / Q000032:analysis / Q000737:chemistry* / Q000494:pharmacology; D016722:Cermet Cements / Q000737:chemistry; D015169:Colony Count, Microbial; D020770:Compomers; D003188:Composite Resins / Q000737:chemistry; D005459:Fluorides / Q000032:analysis / Q000737:chemistry* / Q000494:pharmacology; D005899:Glass Ionomer Cements / Q000737:chemistry*; D007101:Immersion; D008298:Maleates / Q000737:chemistry; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry; D009391:Nephelometry and Turbidimetry; D019279:Resin Cements / Q000737:chemistry*; D012117:Resins, Synthetic / Q000737:chemistry; D017640:Silicates / Q000737:chemistry; D012965:Sodium Chloride; D013295:Streptococcus mutans / Q000187:drug effects* / Q000254:growth & development; D013997:Time Factors
D002327:Cariostatic Agents; D016722:Cermet Cements; D020770:Compomers; D003188:Composite Resins; C088486:Dyract; D005899:Glass Ionomer Cements; D008298:Maleates; D008689:Methacrylates; C081144:Photac-Fil; D019279:Resin Cements; D012117:Resins, Synthetic; D017640:Silicates; C084550:Vitremer; C084541:Fuji glass-ionomer lining cement; D012965:Sodium Chloride; C040964:Ketac-Fil; D005459:Fluorides