New horizons in sequence analysis.
An ever increasing number of protein sequences are being compared, partly because of the availability of full sets of protein sequences from several completed genome-sequencing projects. The resulting problem of scale has shifted the emphasis of sequence analysis method development from sensitivity and flexibility, which relies on manual intervention and interpretation, to the automatic generation of results of known reliability.
Hubbard
T J
TJ
Sanger Centre, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire, CB10 1SA, UK. th@sanger.ac.uk
D000595:Amino Acid Sequence; D008390:Markov Chains; D010449:Peptide Mapping / Q000379:methods*; D017421:Sequence Analysis / Q000379:methods*