Intraarterial injection of amrinone for vasospasm induced by subarachnoid hemorrhage.
We describe two patients who had cerebral vasospasm after subarachnoid hemorrhage that was refractory to intraarterial injection of papaverine. Both patients were successfully treated with intraarterial injection of amrinone after intraarterial injection of papaverine. It is suggested that intraarterial amrinone, which has a vasodilatory action, may be therapeutically useful for cerebral vasospasm.
Yoshida
K
K
Department of Neurological Surgery, Nihon University, Nerima Hikarigaoka Hospital, Tokyo, Japan.
Watanabe
H
H
Nakamura
S
S
D000328:Adult; D000676:Amrinone / Q000008:administration & dosage*; D017542:Aneurysm, Ruptured / Q000175:diagnosis / Q000601:surgery*; D001921:Brain / Q000098:blood supply; D002533:Cerebral Angiography; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007269:Injections, Intra-Arterial; D002532:Intracranial Aneurysm / Q000175:diagnosis / Q000601:surgery*; D002546:Ischemic Attack, Transient / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D010208:Papaverine / Q000008:administration & dosage; D012039:Regional Blood Flow / Q000187:drug effects; D013345:Subarachnoid Hemorrhage / Q000175:diagnosis / Q000601:surgery*; D015899:Tomography, Emission-Computed, Single-Photon; D017211:Treatment Failure; D014665:Vasodilator Agents / Q000008:administration & dosage*
D014665:Vasodilator Agents; D010208:Papaverine; D000676:Amrinone