title: Interactions between enteropathogenic Escherichia coli and host epithelial cells.
abstract: The pathogenesis of enteropathogenic Escherichia coli (EPEC) infection is emerging as a paradigm for a multistage microorganism-host cell interaction. Both type IV fimbriae and a type III secretion apparatus play principal roles in interactions between the bacteria and host cells. Recent data suggest that bacteria-induced signal transduction activates the receptor that allows tenacious adherence of the bacteria to the host cell surface.
authors.affiliation: Divn of Infectious Diseases, University of Maryland School of Medicine, Baltimore 21201, USA. mdonnenb@umabnet.ab.umd.edu
authors.forename: M S
authors.initials: MS
authors.lastname: Donnenberg
authors.forename: J B
authors.initials: JB
authors.lastname: Kaper
authors.forename: B B
authors.initials: BB
authors.lastname: Finlay
mesh_terms: D001422:Bacterial Adhesion; D001426:Bacterial Proteins / Q000378:metabolism; D003967:Diarrhea / Q000382:microbiology / Q000503:physiopathology; D004847:Epithelial Cells; D004926:Escherichia coli / Q000472:pathogenicity*; D006801:Humans; D015398:Signal Transduction; D014774:Virulence
chemical_list: D001426:Bacterial Proteins