title: [The morphofunctional characteristics of the hypothalamo-hypophyseal-gonadal system in male rats under emotional pain stress (EPS)].
abstract: Hypothalamus, hypophysis and testis of the rat were studied in conditions of emotional pain stress using light and electron microscopy, radioautography, radioimmunological and morphometrical methods. Hypothalamo-hypophyseal neurosecretory system activates significantly when affected by stress factors. Somatotroprocytes, corticotropocytes and thyrotropocytes activate in adenohypophysis. Membrane damage and decrease of synthetic and exocytosis processes was found in gonadotropocytes. Endocrine and spermatogenic functions of testis were impaired. Leydig cells cytoplasm and nucleus grow smaller in size, mitochondrial matrix becomes more dense, membrane structure destruction and cytoplasm vascularization occur. Heteromorphism increases in endocrinocyte population. Disintegration of secretory processes in endocrinocytes causes reduction of testosterone amount in blood.
authors.forename: A A
authors.initials: AA
authors.lastname: Stadnikov
authors.forename: N N
authors.initials: NN
authors.lastname: Shevliuk
mesh_terms: D000818:Animals; D001362:Avoidance Learning; D003214:Conditioning, Classical; D004558:Electric Stimulation; D007030:Hypothalamo-Hypophyseal System / Q000503:physiopathology* / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D010146:Pain / Q000473:pathology / Q000503:physiopathology*; D051381:Rats; D013315:Stress, Psychological / Q000473:pathology / Q000503:physiopathology*; D013737:Testis / Q000503:physiopathology* / Q000648:ultrastructure; D013997:Time Factors
vernacular_title: Morfofunktsional'naia kharakteristika gipotalamo-gipofizarno-gonadnoĭ sistemy krys-samtsov v usloviiakh émotsional'no-bolevogo stressa (EBS)]