title: Vertical transmission of human immunodeficiency virus.
abstract: We discuss the interactions between mother and infant that influence the transmission of HIV. Potential routes of infection are identified, and maternal and infant risk factors for transmission are explored. The role of the immune system in controlling HIV infection in the infant is discussed. Finally, preventive measures for reducing vertical transmission are proposed and evaluated.
authors.affiliation: Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford, UK.
authors.forename: J
authors.initials: J
authors.lastname: Morrison
authors.forename: N J
authors.initials: NJ
authors.lastname: Alp
mesh_terms: D019380:Anti-HIV Agents / Q000627:therapeutic use; D001942:Breast Feeding; D036861:Delivery, Obstetric; D005260:Female; D015658:HIV Infections / Q000276:immunology / Q000517:prevention & control / Q000635:transmission*; D015497:HIV-1; D015498:HIV-2; D006801:Humans; D007231:Infant, Newborn / Q000276:immunology; D018445:Infectious Disease Transmission, Vertical; D008429:Maternal Welfare; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D012307:Risk Factors; D015215:Zidovudine / Q000627:therapeutic use
chemical_list: D019380:Anti-HIV Agents; D015215:Zidovudine