Bactericidal eradication from carious lesions of prepared abutments by an antibacterial temporary cement.
OBJECTIVE
The aim of this study was to observe the antibacterial potential of polycarboxylate temporary cement containing a mixture of metronidazole, ciprofloxacin, and cefaclor on carious lesions of prepared abutments that were designed to leave caries on the abutments.


METHODS
Antibacterial efficacy was estimated in vitro and in vivo by measuring bacterial recovery from the lesions. Bacteria counts ranged from 10(4) to 10(7) both in vitro (nine samples) and in vivo (five samples) in time-zero samples, just before the application of the antibacterial cement.


RESULTS
No bacteria were recovered from carious lesions in vitro (six samples) or in vivo (four samples) after the lesions were covered by the antibacterial temporary cement. For the remaining samples, some bacteria (5 to 80 counts per sample) were recovered, with one notable exception in which marginal leakage provided a bacteria count of 10(3). Bacteria counts ranging from 10(3) to 10(5) occurred in carious lesions covered by temporary cement without antibacterial agents, which indicated that temporary cement alone was not a potent disinfectant.


CONCLUSIONS
The results of this study indicated that the antibacterial temporary cement can be useful for eradicating bacteria from carious lesions of prepared abutments.
Hori
R
R
Department of Removable Prosthodontics, Niigata University School of Dentistry, Japan.
Kohno
S
S
Hoshino
E
E
D000328:Adult; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000627:therapeutic use*; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D002433:Cefaclor / Q000627:therapeutic use; D002511:Cephalosporins / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D015169:Colony Count, Microbial; D003442:Crowns; D000044:Dental Abutments; D003731:Dental Caries / Q000382:microbiology* / Q000628:therapy; D003763:Dental Leakage / Q000382:microbiology; D003794:Dental Restoration, Temporary; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use; D008875:Middle Aged; D011076:Polycarboxylate Cement / Q000737:chemistry / Q000627:therapeutic use*; D019231:Tooth Preparation, Prosthodontic
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D011076:Polycarboxylate Cement; D008795:Metronidazole; D002939:Ciprofloxacin; D002433:Cefaclor