[The use of the antihypoxants olifen and amtizol for treating patients with chronic stage-IIB circulatory failure].
To compare efficacy of conventional therapy, antihypoxants olifen and amthizol (groups 1, 2 and 3, respectively) 49 patients with congestive heart failure stage IIb according to the Vasilenko-Strazhesko classification were treated. In hospital the pre-hospital scheme of treatment was not changed except the following positions: group 1 patients received strophanthin instead of oral digoxin, group 2 and 3 patients received adjuvant olifen and amthizol, respectively. Stabilization of the condition occurred in 10 days, on the average, in each group. In the 1st group good results were obtained due to stroke volume increase, in the 2nd and 3d due to the ability of olifen and amthizol to prevent tissue hypoxia.
Andrianov
V P
VP
Boĭtsov
S A
SA
Smirnov
A V
AV
Shalin
I M
IM
Tomchin
A B
AB
Zakharova
A I
AI
Ivanova
V A
VA
Bulyko
T M
TM
D000975:Antioxidants / Q000627:therapeutic use*; D002311:Cardiomyopathy, Dilated / Q000150:complications; D002908:Chronic Disease; D004341:Drug Evaluation; D004359:Drug Therapy, Combination; D006333:Heart Failure / Q000097:blood / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications; D010647:Phenyl Ethers / Q000627:therapeutic use*; D011788:Quality of Life; D012214:Rheumatic Heart Disease / Q000150:complications; D013830:Thiadiazoles / Q000627:therapeutic use*
D000975:Antioxidants; D010647:Phenyl Ethers; D013830:Thiadiazoles; C085806:olifen; C044365:amtizol
Primenenie antigipoksantov olifena i amtizola dlia lecheniia bol'nykh a khronicheskoĭ nedostatochnost'iu krovoobrashcheniia IIB stadii.