title: [Tetanus: problems of differential diagnosis in the presence of contemporaneous administration of metoclopramide].
abstract: Here we report a clinical case concerning differential diagnosis between tetanus and metoclopramide intoxication. A 67 year old woman was admitted to our intensive care unit complaining of both trisma and four limbs hypertone soon after a massive metoclopramide bolus administration. The patient was affected by a chronicle renal insufficiency and a diagnosis of metoclopramide intoxication was made. The long lasting dystonic symptomatology together with respiratory insufficiency ruled out the hypothesis of drug overdose. The intensive care physicians would take into account that at least a 24 hours clinical observation is mandatory in order to perform a correct diagnosis.
authors.affiliation: Istituto di Anestesiologia e Rianimazione, Università Cattolica del Sacro Cuore, Roma.
authors.forename: R
authors.initials: R
authors.lastname: Gaspari
authors.forename: V
authors.initials: V
authors.lastname: Mignani
authors.forename: A
authors.initials: A
authors.lastname: Kovacs
authors.forename: A
authors.initials: A
authors.lastname: Clemente
authors.forename: M
authors.initials: M
authors.lastname: Visocchi
authors.forename: R
authors.initials: R
authors.lastname: Proietti
mesh_terms: D000368:Aged; D000932:Antiemetics / Q000506:poisoning*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D008787:Metoclopramide / Q000506:poisoning*; D013742:Tetanus / Q000175:diagnosis*; D014313:Trismus / Q000209:etiology
chemical_list: D000932:Antiemetics; D008787:Metoclopramide
vernacular_title: Tetano: problemi di diagnosi differenziale in presenza di contemporanea assunzione di metoclopramide.