title: Salivary gland double tumor: synchronous ipsilateral pleomorphic adenoma and acinic cell carcinoma of the parotid gland.
abstract: A 44-year-old woman underwent a partial parotidectomy for a slowly enlarging parotid mass diagnosed by fine needle aspiration biopsy as a pleomorphic adenoma. Though macroscopically recognized to be composed of two nodules, differing to some extent from one another, the mass appeared to constitute a single tumor. The microscopic examination disclosed two disparate neoplasms, which were separated from each other by a thin fibrous band. The larger of the two nodules was a pleomorphic adenoma and the smaller one an acinic cell carcinoma. The metachronous--and, even more, the synchronous--occurrence of two histologically different tumors in one major salivary gland is an exceptional and probably coincidental event.
authors.affiliation: Department of Pathology, Bnai-Zion Medical Center, Haifa, Israel.
authors.forename: I
authors.initials: I
authors.lastname: Misselevich
authors.forename: L
authors.initials: L
authors.lastname: Podoshin
authors.forename: M
authors.initials: M
authors.lastname: Fradis
authors.forename: J H
authors.initials: JH
authors.lastname: Boss
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology* / Q000601:surgery; D000328:Adult; D018267:Carcinoma, Acinar Cell / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery; D010307:Parotid Neoplasms / Q000473:pathology* / Q000601:surgery