title: Parathyroid hyperplasia may be missed by double-phase Tc-99m sestamibi scintigraphy alone.
abstract: The authors report two cases of parathyroid imaging with double-phase Tc-99m sestamibi used in conjunction with Tc-99m pertechnetate that detected parathyroid hyperplasia when the wash out rate of MIBI from the glands paralleled normal thyroid tissue. Routine use of thyroid images for comparison may avoid this pitfall. The authors also observed that Tc-99m sestamibi has early uptake in brown tumors.
authors.affiliation: Department of Radiology, Los Angeles County Harbor-UCLA Medical center, Torrance, California 90509-2910, USA.
authors.forename: E M
authors.initials: EM
authors.lastname: Chen
authors.forename: F S
authors.initials: FS
authors.lastname: Mishkin
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000000981:diagnostic imaging*; D006965:Hyperplasia / Q000000981:diagnostic imaging; D008067:Lipoma / Q000000981:diagnostic imaging*; D008297:Male; D018761:Multiple Endocrine Neoplasia Type 1 / Q000000981:diagnostic imaging*; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging*; D011547:Pseudohypoparathyroidism / Q000000981:diagnostic imaging*; D011859:Radiography; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D013670:Sodium Pertechnetate Tc 99m; D017256:Technetium Tc 99m Sestamibi; D013961:Thyroid Gland / Q000000981:diagnostic imaging; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi; D013670:Sodium Pertechnetate Tc 99m