title: Cytologic features of solid and cystic tumor of the pancreas.
abstract: OBJECTIVE
  To describe the cytologic features of solid and cystic tumor of the pancreas.
  
  
  METHODS
  Cytologic features of four cases of solid and cystic tumor of the pancreas (SCT) were reported and compared with those of three cases of islet cell tumor of the pancreas.
  
  
  RESULTS
  Aspiration and imprint cytology of the tumor cells obtained from three cases of SCT showed papillary structures or rosette formations in part and demonstrated uniformly round to oval nuclei that contained finely granular chromatin, a fairly distinct nucleolus and a scant to moderate amount of granular or vesicular cytoplasm. Another case of SCT consisted of multinucleated giant cells with coherent chromatin as well as mononuclear cells with nuclear grooves. Islet cell tumor consisted mainly of clustered or isolated uniform mononuclear cells with rosette formations but without a papillary structure and occasional multinucleated giant cells in all cases. The nuclei of islet cell tumors had peculiar, fine chromatin aggregates with a "salt-and-pepper" appearance and slightly enlarged nucleoli.
  
  
  CONCLUSIONS
  SCT is cytologically distinguishable from islet cell tumor in spite of having many cytologic features in common with it.
authors.affiliation: Department of Pathology, Oita Medical University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kashima
authors.forename: Y
authors.initials: Y
authors.lastname: Hayashida
authors.forename: S
authors.initials: S
authors.lastname: Yokoyama
authors.forename: J
authors.initials: J
authors.lastname: Nagahama
authors.forename: K
authors.initials: K
authors.lastname: Sato
authors.forename: T
authors.initials: T
authors.lastname: Daa
authors.forename: A
authors.initials: A
authors.lastname: Gamachi
authors.forename: I
authors.initials: I
authors.lastname: Nakayama
mesh_terms: D007516:Adenoma, Islet Cell / Q000473:pathology* / Q000648:ultrastructure; D000293:Adolescent; D000328:Adult; D001707:Biopsy, Needle; D002467:Cell Nucleus / Q000473:pathology / Q000648:ultrastructure; D002843:Chromatin / Q000473:pathology; D005260:Female; D015726:Giant Cells / Q000473:pathology / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008854:Microscopy, Electron; D009375:Neoplasms, Glandular and Epithelial / Q000473:pathology* / Q000648:ultrastructure; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000648:ultrastructure
chemical_list: D002843:Chromatin