[Prevention of virus-related neurological diseases by vaccines].
Prevention of virus-related neurological diseases are surveyed. Patients of poliomyelitis has recently been drastically reduced by world-wide administrating live vaccines. In view of rare incidence of paralysis after giving live vaccine, adoption of inactivated vaccine has recently been reconsidered. A live varicella vaccine was developed and has been world-wide used for normal and high-risk children. Incidence of zoster in vaccinated acute leukemic children is several times higher in those who with rash after vaccination as compared with those without rash, and as no or few rash appears after vaccination of normal children, it is expected that vaccination of normal children would lead to reduction of zoster after their aging. Measles encephalitis has rapidly been reduced by world-wide use of live vaccines. Mouse-brain derived vaccine against Japanese encephalitis(JE) has been used in Asian countries. Development of tissue-culture derived JE vaccine is under way.
Takahashi
M
M
Research Foundation for Microbial Diseases of Osaka University.
D002648:Child; D006801:Humans; D009422:Nervous System Diseases / Q000517:prevention & control*; D014765:Viral Vaccines; D014777:Virus Diseases / Q000517:prevention & control*
D014765:Viral Vaccines