Consolidation of particle beds and packing of chromatographic columns.
A variety of complementary evidence reviewed here demonstrates that the packing of chromatographic columns is heterogeneous. It is denser and less well organized close to the column wall than in the center of the column. The mechanism of particle consolidation under stress explains the origin of this phenomenon and provides a fundamental justification to what is known in column chromatography as "the wall effect".
Guiochon
G
G
Department of Chemistry, University of Tennessee, Knoxville 37996-1600, USA.
Farkas
T
T
Guan-Sajonz
H
H
Koh
J H
JH
Sarker
M
M
Stanley
B J
BJ
Yun
T
T
D002853:Chromatography, Liquid / Q000379:methods*; D012117:Resins, Synthetic / Q000737:chemistry*; D013499:Surface Properties
D012117:Resins, Synthetic