Nonconvulsive status epilepticus during antidepressant treatment.
We report 3 patients who experienced nonconvulsive status epilepticus following generalized convulsions during antidepressant treatment. All showed prolonged confusion with some psychiatric symptoms, and their electroencephalograms (EEGs) showed either bilateral synchronous multiple spike wave discharges or continuous diffuse sharp and slow waves. When diazepam was administered intravenously to 1 patient, the clinical symptoms and EEG improved markedly.
Yoshino
A
A
Department of Psychiatry, National Defense Medical College, Saitama, Japan.
Watanabe
M
M
Shimizu
K
K
Goto
T
T
Ichinowatari
N
N
Yoshimasu
H
H
Masaki
K
K
Aoyama
T
T
Hara
T
T
D000328:Adult; D000368:Aged; D000928:Antidepressive Agents / Q000009:adverse effects*; D003221:Confusion / Q000139:chemically induced; D004359:Drug Therapy, Combination; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D013226:Status Epilepticus / Q000139:chemically induced*
D000928:Antidepressive Agents