title: A case of non-Hodgkin's lymphoma with macroglobulinemia.
abstract: A case of non-Hodgkin's lymphoma with macroglobulinemia is reported. A 48-year-old man consulted our hospital with complaints of dysphagia and sleep apnea. On the first examination, degree III hypertrophy of tonsils, Bence-Jones protein of K-type on urinalysis, and an M-peak in the gamma-glb. Beta-glb areas on fractionation of protein were found. Of serum immunoglobulins, IgM was increased markedly with 3,946 mg/dl and about 30% atypical lymphocytes were noted in the bone marrow. Bilateral tonsillectomy was carried out. The diagnosis of malignant lymphoma, non-Hodgkin, follicular, medium-sized cell type, B cell (sm IgM, K) was made by immunostaining of tissues. Chemotherapy was made after operation, and IgM levels decreased gradually. At present, the patient is following a satisfactory postoperative course, showing no swelling of tonsil.
authors.affiliation: Department of Otolaryngology, The University of Tokushima, School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Abe
authors.forename: Y
authors.initials: Y
authors.lastname: Hori
authors.forename: S Y
authors.initials: SY
authors.lastname: Ohtsu
authors.forename: Y
authors.initials: Y
authors.lastname: Koike
mesh_terms: D015703:Antigens, CD / Q000032:analysis / Q000097:blood; D001853:Bone Marrow / Q000737:chemistry; D005434:Flow Cytometry; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis / Q000097:blood; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000473:pathology / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged; D014066:Palatine Tonsil / Q000737:chemistry / Q000473:pathology / Q000648:ultrastructure; D012891:Sleep Apnea Syndromes / Q000150:complications; D014057:Tomography, X-Ray Computed; D014067:Tonsillar Neoplasms / Q000150:complications* / Q000473:pathology / Q000648:ultrastructure; D008258:Waldenstrom Macroglobulinemia / Q000150:complications*
chemical_list: D015703:Antigens, CD; D007136:Immunoglobulins