title: Graphic analysis of femoral growth in young children with Perthes' disease.
abstract: A cohort of 20 children, younger than 5.5 years at the time of onset of unilateral Perthes' disease, were studied by computer graphic analysis. Graphic outlines derived from each child's series of anterior posterior radiographs of the pelvis and hips were aligned on layers in a computer application such that changes over time could be directly visualized and measured. In these young children, injury to the cartilaginous growth mechanisms accounted for almost all of the abnormal change in the shape of the proximal femur; growth abnormalities had been established by the time of initial radiographs and persisted both as constant growth-rate change and growth-direction change until skeletal maturity. Despite the similar degree of radiographic bone necrosis, outcomes differed, and the specific growth aberrations were highly unique to the individual. At the time of the most recent radiographs, among the diseased hips 7 had spherical femoral heads larger than the normal side, eight had elliptical femoral heads congruent with the acetabulum, and five had elliptical femoral heads with a flat area congruent with the acetabulum. The study did not provide evidence to support a logic for brace or surgical treatment of young children with Perthes' disease.
authors.affiliation: Greenville Unit, Shriners Hospital for Children, SC 29605-4277, USA.
authors.forename: B L
authors.initials: BL
authors.lastname: Allen
mesh_terms: D000293:Adolescent; D002675:Child, Preschool; D015331:Cohort Studies; D003196:Computer Graphics; D004838:Epiphyses / Q000254:growth & development; D005260:Female; D005269:Femur / Q000033:anatomy & histology / Q000254:growth & development*; D006801:Humans; D007223:Infant; D007873:Legg-Calve-Perthes Disease / Q000503:physiopathology*; D008297:Male; D008953:Models, Anatomic; D012189:Retrospective Studies