title: Enantioselective accumulation of (--)-pinoresinol through O-demethylation of (+/-)-eudesmin by Aspergillus niger.
abstract: Microbial transformation of (+/-)-eudesmin by Aspergillus niger was investigated. Enantioselective accumulation of (--)-pinoresinol was shown through O-demethylation of (+/-)-eudesmin. This fungus O- demethylated both enantiomers of eudesmin, but the conversion rates for each enantiomer were clearly different.
authors.affiliation: Department of Applied Chemistry, Faculty of Science and Engineering, Kinki University, Kowakae, Osaka, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kasahara
authors.forename: M
authors.initials: M
authors.lastname: Miyazawa
authors.forename: H
authors.initials: H
authors.lastname: Kameoka
mesh_terms: D001234:Aspergillus niger / Q000378:metabolism*; D001711:Biotransformation; D005663:Furans / Q000378:metabolism / Q000493:pharmacokinetics*; D017705:Lignans; D008745:Methylation; D013237:Stereoisomerism
chemical_list: D005663:Furans; D017705:Lignans; C105875:eudesmin; C103298:pinoresinol