title: Bioactivity of titanium treated with hydrogen peroxide solutions containing metal chlorides.
abstract: Commercially available pure metallic titanium was chemically treated at 60 degrees C for 24 h with H2O2 solutions containing various metal chlorides to provide titanium with bioactivity, that is, to give it the ability to form a biologically active bone-like apatite layer on the surface. After the chemical treatment the titanium specimens were soaked in a simulated body fluid (the Kokubo solution). Apatite was found to deposit on the specimens treated with the H2O2/TaCl5 and H2O2/SnCl2 solutions. X-ray photoelectron spectroscopic (XPS) study of the specimens treated with those H2O2 solutions indicated that basic Ti-OH groups in titania hydrogel layers on their surfaces were responsible for apatite nucleation and growth.
authors.affiliation: Biomaterials Laboratory, Faculty of Engineering, Okayama University, Japan.
authors.forename: C
authors.initials: C
authors.lastname: Ohtsuki
authors.forename: H
authors.initials: H
authors.lastname: Iida
authors.forename: S
authors.initials: S
authors.lastname: Hayakawa
authors.forename: A
authors.initials: A
authors.lastname: Osaka
mesh_terms: D001826:Body Fluids; D018786:Bone Substitutes; D002712:Chlorides; D006801:Humans; D006861:Hydrogen Peroxide; D066298:In Vitro Techniques; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D010949:Plasma; D012996:Solutions; D013499:Surface Properties; D014025:Titanium; D014961:X-Ray Diffraction
chemical_list: D018786:Bone Substitutes; D002712:Chlorides; D012996:Solutions; D006861:Hydrogen Peroxide; D014025:Titanium