title: A second-generation linkage map of the bovine genome.
abstract: We report a bovine linkage map constructed with 1236 polymorphic DNA markers and 14 erythrocyte antigens and serum proteins. The 2990-cM map consists of a sex-specific, X chromosome linkage group and 29 sex-averaged, autosomal linkage groups with an average interval size of 2.5 cM. The map contains 627 new markers and 623 previously linked markers, providing a basis for integrating the four published bovine maps. Orientation and chromosomal assignment of all the linkage groups, except BTA20 and BTA22, was provided by 88 markers that were assigned previously to chromosomes. This map provides sufficient marker density for genomic scans of populations segregating quantitative trait loci (QTL) and subsequent implementation of marker-assisted selection (MAS) mating schemes.
authors.affiliation: U.S. Department of Agriculture (USDA), Agricultural Research Service (ARS), U.S. Meat Animal Research Center, Clay Center, Nebraska 68933-0166, USA. kappes@map.marc.usda.gov
authors.forename: S M
authors.initials: SM
authors.lastname: Kappes
authors.forename: J W
authors.initials: JW
authors.lastname: Keele
authors.forename: R T
authors.initials: RT
authors.lastname: Stone
authors.forename: R A
authors.initials: RA
authors.lastname: McGraw
authors.forename: T S
authors.initials: TS
authors.lastname: Sonstegard
authors.forename: T P
authors.initials: TP
authors.lastname: Smith
authors.forename: N L
authors.initials: NL
authors.lastname: Lopez-Corrales
authors.forename: C W
authors.initials: CW
authors.lastname: Beattie
mesh_terms: D000818:Animals; D001798:Blood Proteins; D002417:Cattle; D002874:Chromosome Mapping; D002875:Chromosomes / Q000235:genetics; D004247:DNA / Q000032:analysis; D004912:Erythrocytes; D008040:Genetic Linkage; D005819:Genetic Markers; D015698:Genomic Library; D018895:Microsatellite Repeats; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D014960:X Chromosome / Q000235:genetics; D014998:Y Chromosome / Q000235:genetics
chemical_list: D001798:Blood Proteins; D005819:Genetic Markers; D004247:DNA