Valproate-induced developmental modifications maybe partially prevented by coadministration of folinic acid and S-adenosylmethionine.
Ubeda
N
N
Departamento de Ciencias Morfológicas I, Facultad de Medicina, Universidad Complutense, Madrid, Spain.
Alonso
E
E
Martín-Rodríguez
J C
JC
Varela-Moreiras
G
G
Puerta
J
J
Pérez-Miguelsanz
J
J
D000014:Abnormalities, Drug-Induced / Q000517:prevention & control*; D000818:Animals; D000927:Anticonvulsants / Q000037:antagonists & inhibitors* / Q000633:toxicity*; D001842:Bone and Bones / Q000002:abnormalities; D005260:Female; D005333:Fetus / Q000187:drug effects / Q000378:metabolism; D002955:Leucovorin / Q000008:administration & dosage* / Q000378:metabolism; D008099:Liver / Q000187:drug effects / Q000378:metabolism; D008715:Methionine / Q000378:metabolism; D008745:Methylation; D009436:Neural Tube Defects / Q000517:prevention & control; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar; D012436:S-Adenosylmethionine / Q000008:administration & dosage* / Q000378:metabolism; D014635:Valproic Acid / Q000037:antagonists & inhibitors* / Q000633:toxicity*
D000927:Anticonvulsants; D014635:Valproic Acid; D012436:S-Adenosylmethionine; D008715:Methionine; D002955:Leucovorin