title: Cronkhite-Canada syndrome associated with carcinoma of the sigmoid colon: report of a case.
abstract: Cronkhite-Canada syndrome is generally accepted as being a benign disorder. We herein present a 66-year-old-male patient with Cronkhite-Canada syndrome who had a carcinoma of the sigmoid colon along with multiple colonic polyps, which included juvenile-type polyps, adenomas, and hyperplastic polyps. In the world literature, there have been 34 cases of Cronkhite-Canada syndrome associated with colorectal carcinoma among the 280 reported cases of this syndrome. This report thus adds to the growing evidence that Cronkhite-Canada syndrome may be a premalignant condition for colorectal carcinoma. A periodic examination of the colon is therefore advised in order to detect any development of colorectal carcinoma at an early stage.
authors.affiliation: Department of Surgery, Himi City Hospital, Toyama, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Nakatsubo
authors.forename: R
authors.initials: R
authors.lastname: Wakasa
authors.forename: K
authors.initials: K
authors.lastname: Kiyosaki
authors.forename: K
authors.initials: K
authors.lastname: Matsui
authors.forename: F
authors.initials: F
authors.lastname: Konishi
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000368:Aged; D006801:Humans; D007417:Intestinal Polyps / Q000473:pathology*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D012811:Sigmoid Neoplasms / Q000473:pathology*