Apnea prolongation via short-term inhibition.
Central apneas during sleep are frequently of longer duration than predicted and persist despite high levels of chemical stimuli. We provide evidence that suggests that this apnea prolongation represents a central inertia in the control system mediated by reciprocal inhibition of inspiration.
Dempsey
J A
JA
John Rankin Laboratory of Pulmonary Medicine, Department of Preventive Medicine, University of Wisconsin-Madison 53706, USA.
Leevers
A M
AM
Wilson
C R
CR
Harms
C A
CA
Smith
C A
CA
D000818:Animals; D001049:Apnea; D004285:Dogs; D004576:Electromyography; D006801:Humans; D008568:Memory; D012121:Respiration, Artificial; D012895:Sleep, REM; D013997:Time Factors; D015919:Ventilators, Negative-Pressure; D014851:Wakefulness