title: Rectal diclofenac analgesia after abdominal hysterectomy.
abstract: Sixty-two patients undergoing total abdominal hysterectomy with or without salpingo-oophorectomy were randomly allocated to received either 100 mg rectally of diclofenac (n = 31) or a placebo (n = 31) at the end of the operation and 12-hourly for 72 hours postoperatively. The analgesic effect of the diclofenac was measured by a visual analogue scale pain score and morphine usage. Patients receiving diclofenac showed a morphine requirement of < 50% of the patients receiving placebo (p < 0.0001). There was no statistical evidence of any reduction in the incidence of nausea and vomiting with the use of diclofenac.
authors.affiliation: Southern Cross Hospital, Napier, New Zealand.
authors.forename: R M
authors.initials: RM
authors.lastname: Scott
authors.forename: P N
authors.initials: PN
authors.lastname: Jennings
mesh_terms: D000698:Analgesia; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D004008:Diclofenac / Q000627:therapeutic use*; D005187:Fallopian Tubes / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D009020:Morphine / Q000627:therapeutic use; D009294:Narcotics / Q000627:therapeutic use; D010052:Ovariectomy; D010147:Pain Measurement; D013488:Suppositories
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D009294:Narcotics; D013488:Suppositories; D004008:Diclofenac; D009020:Morphine