title: Endometriosis is not detrimental to embryo implantation in oocyte recipients.
abstract: OBJECTIVE
  Our purpose was to determine the effects of endometriosis on implantation and pregnancy rates in ovum recipients.
  
  
  METHODS
  The medical records of 239 consecutive oocyte recipient patients who were treated between January 1, 1991, and June 30, 1995, were analyzed retrospectively. Recipients with endometriosis (group 1; n = 55) were compared to recipients without endometriosis (group II; n = 184). Patients in group I had active endometriotic disease confirmed by laparoscopy and were subdivided into mild (Stages I and II; n = 18) and moderate to severe (Stages III and IV; n = 37) endometriosis.
  
  
  RESULTS
  No difference was found in recipient age, endometrial thickness, donor age, and embryos transferred. The pregnancy rates (28 versus 29%) and implantation rates (12 and 13%) were also comparable between group I and group II, as well as between patients with mild and patients with moderate to severe endometriosis.
  
  
  CONCLUSIONS
  The presence of endometriosis in oocyte recipients does not lower implantation or pregnancy rates. We conclude that the adverse effect of endometriosis on reproductive outcome is not related to implantation but, in fact, is most likely an effect on oocyte or embryo quality.
authors.affiliation: Department of Obstetrics and Gynecology, Mount Sinai School of Medicine, New York, New York 10029, USA.
authors.forename: L
authors.initials: L
authors.lastname: Sung
authors.forename: T
authors.initials: T
authors.lastname: Mukherjee
authors.forename: T
authors.initials: T
authors.lastname: Takeshige
authors.forename: M
authors.initials: M
authors.lastname: Bustillo
authors.forename: A B
authors.initials: AB
authors.lastname: Copperman
mesh_terms: D000328:Adult; D000367:Age Factors; D010064:Embryo Implantation / Q000502:physiology*; D004624:Embryo Transfer / Q000706:statistics & numerical data*; D004715:Endometriosis / Q000503:physiopathology*; D004717:Endometrium / Q000473:pathology / Q000502:physiology; D005260:Female; D005307:Fertilization in Vitro / Q000706:statistics & numerical data; D006801:Humans; D008875:Middle Aged; D018587:Oocyte Donation; D011247:Pregnancy; D018873:Pregnancy Rate