Cortisol as an indicator of severity of parasitic infections of Haemonchus contortus in lambs (Ovis aries).
Two experiments were conducted with lambs to examine the effects of experimental infections of Haemonchus contortus on circulating cortisol levels. In both experiments, naive lambs were divided into three groups based on inoculum doses of 0 (control), 2000 (low dose) and 20,000 (high dose) infective larvae. In experiment 1, the lambs were sampled once daily from day 1 post-inoculation (p.i.) until day 39 p.i. Lambs from the high-dose group had significantly higher sustained levels of cortisol throughout the course of the infection than either the low-dose group or control lambs. In experiment 2, blood was sampled at 30-min intervals for 4 hr on day 21 p.i. The high-dose group also had highest cortisol levels. The consequences of chronic stress and the resultant elevated cortisol concentrations potentially could compromise animal health and animal well-being.
Fleming
M W
MW
Immunology and Disease Resistance Laboratory, U. S. Department of Agriculture, Beltsville, MD 20705, USA. MFLEMING@ggpl.arsusda.gov
D000818:Animals; D005260:Female; D006188:Haemonchiasis / Q000150:complications / Q000469:parasitology / Q000662:veterinary*; D006189:Haemonchus / Q000502:physiology*; D006854:Hydrocortisone / Q000097:blood*; D007814:Larva / Q000502:physiology; D008297:Male; D012756:Sheep; D012757:Sheep Diseases / Q000097:blood / Q000469:parasitology*; D013312:Stress, Physiological / Q000175:diagnosis / Q000209:etiology / Q000662:veterinary*
D006854:Hydrocortisone