title: Borna disease virus antibodies and the deficit syndrome of schizophrenia.
abstract: We detected anti-Borna disease virus (BDV) antibodies at a 14.4% rate in patients with schizophrenia. The hypothesis of a higher rate of BDV seropositivity in deficit syndrome was borne out in a subset of 64 patients categorized according to the Schedule for the Deficit Syndrome with 5/15 seropositive deficit and 4/49 seropositive nondeficit (p < 0.05). This suggests that the antibodies and possibly a BDV-like virus are pathogenetically linked to this form of schizophrenia.
authors.affiliation: Maryland Psychiatric Research Center, Department of Psychiatry, University of Maryland at Baltimore, Catonsville 21228, USA.
authors.forename: R W
authors.initials: RW
authors.lastname: Waltrip
authors.forename: R W
authors.initials: RW
authors.lastname: Buchanan
authors.forename: W T
authors.initials: WT
authors.lastname: Carpenter
authors.forename: B
authors.initials: B
authors.lastname: Kirkpatrick
authors.forename: A
authors.initials: A
authors.lastname: Summerfelt
authors.forename: A
authors.initials: A
authors.lastname: Breier
authors.forename: S A
authors.initials: SA
authors.lastname: Rubin
authors.forename: K M
authors.initials: KM
authors.lastname: Carbone
mesh_terms: D000328:Adult; D000342:Affective Symptoms / Q000821:virology*; D001891:Borna disease virus / Q000276:immunology*; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D003072:Cognition Disorders / Q000821:virology*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D012559:Schizophrenia / Q000145:classification / Q000821:virology*; D013577:Syndrome