[The genetic typing of Corynebacterium diphtheriae strains by the polymerase chain reaction with universal primers].
The use of polymerase chain reaction (UP-PCR with universal primers for the genetic typing of 85 C. diphtheriae strains, isolated from patients and carriers at the period of the epidemic, has shown that a single natural clone of biovar gravis seems to prevail in North Western Russia. UP-PCR is an effective too for the rapid intraspecific typing of strains on the molecular-genetic level and for the study of the circulation of C.diphtheriae epidemic clones.
Mokrousov
I V
IV
Narvskaia
O V
OV
Tseneva
G Ia
GIa
Mikhaĭlov
N V
NV
Popel'
I R
IR
D001483:Base Sequence; D002353:Carrier State / Q000382:microbiology; D003353:Corynebacterium diphtheriae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D017931:DNA Primers; D004269:DNA, Bacterial / Q000235:genetics; D004165:Diphtheria / Q000382:microbiology; D005838:Genotype; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction / Q000379:methods*
D017931:DNA Primers; D004269:DNA, Bacterial
Geneticheskoe tipirovanie shtammov Corynebacterium diphtheriae metodom polimeraznoĭ tsepnoĭ reaktsii s universal'nymi praĭmerami.