title: A prospective randomized study comparing exclusion technique and endoaneurysmorrhaphy for treatment of infrarenal aortic aneurysm.
abstract: OBJECTIVE
  The retroperitoneal approach used in aortic replacement for infrarenal aortic aneurysm has become an important part of the vascular surgeon's armamentarium. Use of the exclusion and bypass technique, however, remains controversial. Although benefits may include reduced blood loss, less operative dissection, and a smoother intraoperative and postoperative course, critics of this technique have alluded to potential drawbacks. In this study the results of the exclusion technique and open endoaneurysmorrhaphy for surgical treatment of abdominal aortic aneurysm were compared.
  
  
  METHODS
  One hundred patients were randomized to either exclusion (EXC) or open endoaneurysmorrhaphy (OP) procedures. A posterolateral left retroperitoneal approach was used in all patients. During surgery, autotransfusion devices were used when needed. Doppler flow and pressures in the excluded aneurysm sac were determined during surgery in EXC to evaluate the completeness of the exclusion.
  
  
  RESULTS
  Patient demographics were similar between the two groups. The mean age was 70 years (range, 53 to 89 years). The operative mortality rates were 0% and 1.9% (1 of 51) in the EXC and OP groups, respectively. Nonfatal postoperative complications occurred in 10.2% (5 of 49) of the EXC group and in 23.5% (12 of 51) of the OP group (p < 0.05). Aneurysm sacs were opened in two EXC procedures. Blood loss (mean +/- SD) was 703 +/- 570 ml in the EXC group and 1031 +/- 703 ml in the OP group (p < or = 0.01). The intensive care unit stay (mean +/- SD) was 1.9 +/- 1.2 days in the EXC group and 3.2 +/- 6.9 days in the OP group (p = NS). The hospital stay (mean +/- SD) was 9.8 +/- 5.8 days and 12.1 +/- 17 days in the EXC and OP groups, respectively (p = NS). There has been persistent flow in the excluded sac in two patients, with sac enlargement in one of these patients on postoperative follow-up by duplex scan or clinical examination.
  
  
  CONCLUSIONS
  The exclusion and bypass technique for repair of infrarenal aortic aneurysm appeared to be an acceptable technique and was associated with less operative blood loss and fewer postoperative complications than those of open aortic endoaneurysmorrhaphy. Exclusion bypass may contribute to a smoother perioperative course and postoperative treatment of these patients.
authors.affiliation: Section of Vascular Surgery, Albany Medical College, NY 12208, USA.
authors.forename: P S
authors.initials: PS
authors.lastname: Paty
authors.forename: R C
authors.initials: RC
authors.lastname: Darling
authors.forename: B B
authors.initials: BB
authors.lastname: Chang
authors.forename: D M
authors.initials: DM
authors.lastname: Shah
authors.forename: R P
authors.initials: RP
authors.lastname: Leather
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery*; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011446:Prospective Studies; D014656:Vascular Surgical Procedures / Q000379:methods / Q000401:mortality