Interstitial deletion of 6q21-q23 associated with split hand.
We report on a 7-month-old boy with interstitial deletion of 6q21-q23 and split-hand defect. He died at 7 months. This is the fifth patient with distal limb anomaly associated with a rearrangement of 6q21 region, and supports previous suggestions that there may be candidate gene(s) for distal limb development in the 6q21 region.
Tsukahara
M
M
School of Allied Health Sciences, Yamaguchi University, Ube, Japan.
Yoneda
J
J
Azuma
R
R
Nakashima
K
K
Kito
N
N
Ouchi
K
K
Kanehara
Y
Y
D002872:Chromosome Deletion; D002896:Chromosomes, Human, Pair 6; D006228:Hand Deformities, Congenital / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male