title: Relation of the flow field distal to a moderate stenosis to the Doppler power.
abstract: An experimental investigation was undertaken to establish how different flow regimes affect the Doppler signal. A rigid tube model consisting of a 70% asymmetric area stenosis was used with steady and pulsatile flow conditions. The characteristics of the flow field at various sites was determined using a photochromic flow visualization method. Continuous-wave Doppler measurements were made using a 41% suspension of human red blood cells (RBCs) in saline as well as a dilute suspension of 4% fixed RBCs. For steady flow, the photochromic results indicated that for Reynolds numbers (Re) of 545 and 1410, turbulence was generated and the length of the turbulent region was found to increase with increasing Re. Under pulsatile flow conditions, turbulence was triggered around peak systole and began to dissipate in late deceleration, and by the end of diastole the flow field almost relaminarized. During the turbulent phase of the flow cycle, the poststenotic flow field was seen to consist of four distinct flow regimes similar to those observed for steady flow. For higher Womersley parameters and Reynolds numbers the turbulent zone was found to be larger and to occupy a greater fraction of the flow cycle. These flow visualization results were compared with the Doppler power measurements made at the same locations and under similar flow conditions. At physiological hematocrits (41%) the onset of turbulence for both steady and pulsatile flow increased the backscattered Doppler power. The location of the peak Doppler power coincided with the region of maximum turbulence observed using the photochromic technique.
authors.affiliation: Institute of Biomedical Engineering, University of Toronto, Canada.
authors.forename: P A
authors.initials: PA
authors.lastname: Bascom
authors.forename: K W
authors.initials: KW
authors.lastname: Johnston
authors.forename: R S
authors.initials: RS
authors.lastname: Cobbold
authors.forename: M
authors.initials: M
authors.lastname: Ojha
mesh_terms: D003251:Constriction, Pathologic; D004301:Doppler Effect; D006801:Humans; D008954:Models, Biological; D011673:Pulsatile Flow; D014463:Ultrasonography; D014652:Vascular Diseases / Q000000981:diagnostic imaging*