title: Plasma cytokines in graft vs host disease and complications following bone marrow transplantation.
abstract: A cohort of 201 autologous or allogeneic bone marrow transplanted (BMT) patients were included for studying the evolution of circulating tumor necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6) by means of repeated plasma determinations. IL-6 levels were high during major transplant-related complications (TRC) or severe graft vs host disease (GVHD). High levels of TNF-alpha seemed to be associated with chronic GVHD but not with acute GVHD or TRC.
authors.affiliation: Département de Biochimie Médicale et Biologie Moléculaire, Université de Bordeaux 2, France.
authors.forename: A N
authors.initials: AN
authors.lastname: Abdallah
authors.forename: J M
authors.initials: JM
authors.lastname: Boiron
authors.forename: Y
authors.initials: Y
authors.lastname: Attia
authors.forename: A
authors.initials: A
authors.lastname: Cassaigne
authors.forename: J
authors.initials: J
authors.lastname: Reiffers
authors.forename: A
authors.initials: A
authors.lastname: Iron
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D002648:Child; D016207:Cytokines / Q000097:blood*; D005260:Female; D006086:Graft vs Host Disease / Q000097:blood* / Q000209:etiology; D019337:Hematologic Neoplasms / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D016207:Cytokines