title: Fast Fourier transform analysis of dynamic data: sine wave stress-strain analysis of biological tissue.
abstract: We propose an improvement to the dynamic oscillation method using as an example the measurement of the tensile stiffness of the rabbit tracheal mucosal membrane. A sine wave oscillation technique was used to study the tissue mechanical properties. A mathematical model was developed using fast Fourier analysis. After mathematically eliminating the machine response, this analysis reveals the tissue frequency response over a wide range of frequencies. This study addresses the advantages of using Fourier analysis to interpret dynamic properties of biological tissue and provides a complete description of how to obtain the pure tissue response.
authors.affiliation: Department of Chemical Engineering, University of British Columbia, Vancouver, Canada.
authors.forename: L
authors.initials: L
authors.lastname: Wang
authors.forename: J L
authors.initials: JL
authors.lastname: Bert
authors.forename: M
authors.initials: M
authors.lastname: Okazawa
authors.forename: P D
authors.initials: PD
authors.lastname: Paré
authors.forename: K L
authors.initials: KL
authors.lastname: Pinder
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D015194:Diffusion Chambers, Culture / Q000379:methods; D005260:Female; D005583:Fourier Analysis; D008954:Models, Biological; D009092:Mucous Membrane; D011817:Rabbits; D013314:Stress, Mechanical; D014132:Trachea / Q000502:physiology*