title: [Infected pseudarthrosis].
abstract: Sequestrectomy, fragment fixation, wound treatment and bone grafting are the old principles of infected non union surgery. Today these principles are the frame, which contents a more aggressive treatment. Sequestrectomy is a radical excision of the complete infected bone-soft-tissue-scar, the resulting defects are covered by one of the various techniques (skin-traction, flap surgery, bone shifting, etc.). Out of 71 infected non unions, treated by radical resection and bone segment transport, healing rate without recurrence of infection was 94%, in 3 additional patients (4%) amputation was performed. For bone fragment fixation, a non devastating implant, like external fixateur, is preferred. To close the wound, the law of avoiding a dead space is used. Defects are closed by muscle flaps, by fragment shortening or by a antibiotic spacer temporarily. The skin is closed by skin-traction techniques or with flap surgery. After soft tissue healing, small bone defects are filled by autografts, defects of more than 3-4 cm with transported segments. Previous limb shortening to close bone defects, with a lengthening later in a "healthy" region, is also possible. Local antibiotic wound treatment cases a significant reduction of the contamination rate, improved dressing techniques support wound healing free of infection. This therapeutic techniques are comparable to open fracture treatment, where by similar surgery a very low infection rate can be achieved.
authors.affiliation: Chirurgische Klinik und Poliklinik, Universitätklinik Bochum.
authors.forename: A
authors.initials: A
authors.lastname: Ekkernkamp
authors.forename: G
authors.initials: G
authors.lastname: Muhr
authors.forename: C
authors.initials: C
authors.lastname: Josten
mesh_terms: D000671:Amputation, Surgical; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D016025:Bone Transplantation; D003131:Combined Modality Therapy; D003646:Debridement; D016267:External Fixators; D005593:Fracture Fixation, Internal; D017102:Fracture Healing / Q000502:physiology; D005599:Fractures, Ununited / Q000601:surgery*; D006801:Humans; D010019:Osteomyelitis / Q000601:surgery*; D011542:Pseudarthrosis / Q000601:surgery*; D012086:Reoperation; D013524:Surgical Flaps
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Die infizierte Pseudarthrose.