title: Interstitial deletion of 6q21-q23 associated with split hand.
abstract: We report on a 7-month-old boy with interstitial deletion of 6q21-q23 and split-hand defect. He died at 7 months. This is the fifth patient with distal limb anomaly associated with a rearrangement of 6q21 region, and supports previous suggestions that there may be candidate gene(s) for distal limb development in the 6q21 region.
authors.affiliation: School of Allied Health Sciences, Yamaguchi University, Ube, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Tsukahara
authors.forename: J
authors.initials: J
authors.lastname: Yoneda
authors.forename: R
authors.initials: R
authors.lastname: Azuma
authors.forename: K
authors.initials: K
authors.lastname: Nakashima
authors.forename: N
authors.initials: N
authors.lastname: Kito
authors.forename: K
authors.initials: K
authors.lastname: Ouchi
authors.forename: Y
authors.initials: Y
authors.lastname: Kanehara
mesh_terms: D002872:Chromosome Deletion; D002896:Chromosomes, Human, Pair 6; D006228:Hand Deformities, Congenital / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male