Recovery and repair issues after stroke from the scientific perspective.
Animal and human studies have shown that motor and somatosensory cortex are capable of reorganization throughout adult life. Cortical reorganization has been associated with functional recovery in experimental and human stroke. Retraining after experimental cortical infarction has been shown to extend cortical representation of the infarcted area and improve skilled motor performance.
Seil
F J
FJ
VA Office of Regeneration Research Programs, Veterans Affairs Medical Center, Portland, OR, USA. seilf@ohsu.edu
D000328:Adult; D000818:Animals; D002544:Cerebral Infarction / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D009044:Motor Cortex / Q000473:pathology / Q000503:physiopathology; D009416:Nerve Regeneration / Q000502:physiology*; D009460:Neurologic Examination; D009473:Neuronal Plasticity / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology; D013003:Somatosensory Cortex / Q000473:pathology / Q000503:physiopathology