title: Disruption of a homolog of trithorax by 11q23 translocations: leukemogenic and transcriptional implications.
authors.affiliation: Department of Pathology, School of Medicine, Stanford University, CA 94305-5324, USA.
authors.forename: P M
authors.initials: PM
authors.lastname: Waring
authors.forename: M L
authors.initials: ML
authors.lastname: Cleary
mesh_terms: D000208:Acute Disease; D002471:Cell Transformation, Neoplastic; D002880:Chromosomes, Human, Pair 11 / Q000235:genetics* / Q000648:ultrastructure; D003001:Cloning, Molecular; D004268:DNA-Binding Proteins / Q000235:genetics* / Q000502:physiology; D015973:Gene Expression Regulation, Leukemic; D005796:Genes; D005801:Genes, Homeobox; D011495:Histone-Lysine N-Methyltransferase; D006801:Humans; D007938:Leukemia / Q000235:genetics*; D007951:Leukemia, Myeloid / Q000139:chemically induced / Q000235:genetics; D051788:Myeloid-Lymphoid Leukemia Protein; D009363:Neoplasm Proteins / Q000502:physiology; D016609:Neoplasms, Second Primary / Q000235:genetics; D015514:Oncogene Proteins, Fusion / Q000502:physiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000235:genetics; D011519:Proto-Oncogenes; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D011995:Recombination, Genetic; D014157:Transcription Factors / Q000235:genetics* / Q000502:physiology; D014158:Transcription, Genetic; D014178:Translocation, Genetic
chemical_list: D004268:DNA-Binding Proteins; C497422:KMT2A protein, human; D009363:Neoplasm Proteins; D015514:Oncogene Proteins, Fusion; D011993:Recombinant Fusion Proteins; D014157:Transcription Factors; D051788:Myeloid-Lymphoid Leukemia Protein; D011495:Histone-Lysine N-Methyltransferase