Selective involvement of basal ganglia and occipital cortex in a patient with acute endosulfan poisoning.
We report a teenage girl with acute endosulfan poisoning who developed psychosis, generalized tonic-clonic seizures, myoclonic jerks, cortical blindness and limb rigidity. Serial magnetic resonance imaging (MRI) showed bilateral reversible lesions localized to caudate nucleus, putamen and occipital cortex; internal capsule and thalamus were spared. This selective involvement may have a bearing on mechanisms underlying endosulfan toxicity.
Pradhan
S
S
Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Pandey
N
N
Phadke
R V
RV
Kaur
A
A
Sharma
K
K
Gupta
R K
RK
D000293:Adolescent; D000927:Anticonvulsants / Q000008:administration & dosage; D001480:Basal Ganglia Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology; D001766:Blindness / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology; D002220:Carbamazepine / Q000008:administration & dosage; D004726:Endosulfan / Q000506:poisoning*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006843:Hydrocarbons, Chlorinated; D007306:Insecticides / Q000506:poisoning*; D008279:Magnetic Resonance Imaging; D009778:Occipital Lobe / Q000503:physiopathology; D013406:Suicide, Attempted
D000927:Anticonvulsants; D006843:Hydrocarbons, Chlorinated; D007306:Insecticides; D002220:Carbamazepine; D004726:Endosulfan