title: Possibilities of gene therapies for cancer.
abstract: Cancer is an acquired disease in which it is possible to identify a variety of abnormalities at a genetic level. This holds a promise that genetic manipulation of tumour cells will lead to novel therapies. As yet these approaches are constrained by available methods for obtaining gene transfer and subsequent genetic control. However, a number of strategies are already reaching the clinic, including attempts at immunotherapy, prodrug activation and improving host defence against conventional chemotherapy. Further clinical opportunities will occur with improved vector development.
authors.forename: L S
authors.initials: LS
authors.lastname: Lashford
mesh_terms: D000818:Animals; D015316:Genetic Therapy / Q000145:classification / Q000379:methods* / Q000639:trends; D006801:Humans; D009369:Neoplasms / Q000235:genetics* / Q000628:therapy*; D009374:Neoplasms, Experimental / Q000235:genetics / Q000628:therapy