title: Learning versus confirming in clinical drug development.
authors.affiliation: Department of Laboratory Medicine, Schools of Pharmacy and Medicine, University of California, San Francisco 94143-0626, USA.
authors.forename: L B
authors.initials: LB
authors.lastname: Sheiner
mesh_terms: D001993:Bronchodilator Agents / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D004345:Drug Industry; D015507:Drugs, Investigational / Q000494:pharmacology; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D012107:Research Design; D012131:Respiratory Insufficiency / Q000188:drug therapy; D013806:Theophylline / Q000627:therapeutic use; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D001993:Bronchodilator Agents; D015507:Drugs, Investigational; D013806:Theophylline