Malignancy-associated membranoproliferative glomerulonephritis.
An 11-year-old girl with an abdominal desmoplastic round cell tumor, treated with chemotherapy, presented with gross hematuria and proteinuria. Renal biopsy revealed type I membranoproliferative glomerulonephritis (MPGN). The association of a malignant tumor and MPGN is extremely unusual in children, and the pathogenesis of the renal lesion under these circumstances is unknown.
Rahman
R C
RC
Department of Nephrology, Hospital de Niños, Superiora Sor Marìa Ludovica, La Plata, Argentina.
Pollono
D
D
Drut
R
R
Spizzirri
F D
FD
D000008:Abdominal Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D005260:Female; D015432:Glomerulonephritis, Membranoproliferative / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology; D018228:Sarcoma, Small Cell / Q000150:complications* / Q000188:drug therapy / Q000473:pathology