title: Desmoplastic and non-desmoplastic ameloblastoma: a comparative clinicopathological analysis.
abstract: OBJECTIVE
  The aim of this study was to review a large series of ameloblastomas, accessioned during a period of 35 years in a single Oral Pathology Diagnostic Center, for the incidence of desmoplastic ameloblastoma (DA) and in order to analyze the clinical features of this unusual variant.
  
  
  METHODS
  All cases diagnosed as ameloblastoma were reviewed and 14 were rediagnosed as DA. These cases were analyzed in terms of gender, patient age, location, clinical diagnosis, radiographic features and recurrence following treatment. Data from DA and non-desmoplastic ameloblastoma (NDA) were compared.
  
  
  RESULTS
  The incidence of DA in this series was 8.8%. The mean age of NDA and DA were 39.1 and 38.8 years respectively, and a higher female prevalence was observed in the latter. The mandible was the most affected bone in both groups of tumors, but with a different regional distribution. Most NDA arose in the angle and ramus of the mandible, but the premolar/molar region was the preferential location for DA. The most common radiographic feature in DA was the osteolytic type, either monolocular or multilocular. Most of these cases were clinically diagnosed as ameloblastoma. According to follow-up data available, 21.4% of DA and 10.1% of NDA recurred.
  
  
  CONCLUSIONS
  The results of this study do not support the hypothesis that DA should be a separate clinicopathological entity. It seems most likely that DA is another histologic variant of ameloblastoma.
authors.affiliation: Oral Pathology Department, Faculty of Odontology, Buenos Aires University, Argentina.
authors.forename: A
authors.initials: A
authors.lastname: Keszler
authors.forename: M L
authors.initials: ML
authors.lastname: Paparella
authors.forename: F V
authors.initials: FV
authors.lastname: Dominguez
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D000564:Ameloblastoma / Q000145:classification* / Q000453:epidemiology / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007573:Jaw Neoplasms / Q000145:classification* / Q000453:epidemiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies; D017678:Sex Distribution; D017154:Stromal Cells / Q000473:pathology