title: Relationship between HLA-C locus and restenosis after coronary artery balloon angioplasty.
abstract: OBJECTIVE
  To determine the relationship between human leukocyte antigen (HLA) loci and restenosis after percutaneous transluminal coronary angioplasty (PTCA).
  
  
  METHODS
  Cross-sectional study in patients treated by PTCA at Juntendo University Hospital, Tokyo, Japan.
  
  
  METHODS
  A total of 65 patients (58 males and 7 females) with coronary artery stenosis who were consecutively selected between October 1994 and June 1995.
  
  
  METHODS
  Significant relationships between the restenosis and the HLA-Cw1.
  
  
  RESULTS
  Among HLA-C locus, Cw1 was negatively related to restenosis (multivariate adjusted odds ratio, 0.19; 95% confidence interval, 0.06-0.63; P=.007).
  
  
  CONCLUSIONS
  In HLA typing, Cw1 may be a useful marker for the prediction of restenosis after PTCA.
authors.affiliation: Department of Cardiology, Juntendo University, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
authors.forename: N
authors.initials: N
authors.lastname: Yamada
authors.forename: H
authors.initials: H
authors.lastname: Yokoi
authors.forename: Y
authors.initials: Y
authors.lastname: Fujiwara
authors.forename: H
authors.initials: H
authors.lastname: Mokuno
authors.forename: H
authors.initials: H
authors.lastname: Daida
authors.forename: H
authors.initials: H
authors.lastname: Yamaguchi
mesh_terms: D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D015415:Biomarkers; D003327:Coronary Disease / Q000235:genetics* / Q000276:immunology / Q000628:therapy*; D003430:Cross-Sectional Studies; D005260:Female; D015236:HLA-C Antigens / Q000235:genetics*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010641:Phenotype; D012008:Recurrence
chemical_list: D015415:Biomarkers; D015236:HLA-C Antigens; C047431:HLA-Cw1 antigen