Investigation of monoclonal antibodies directed against Fy3, Jra, Lub, Kell or Kell related antigens.
Twenty Mabs of human or murine origin were studied. Serological characterization was achieved by the gel technique with common, rare, and enzyme-modified RBCs. Three clones bound to cell surface proteins on immunoblots: 1 anti-Lub and 2 Mabs raised to a purified Kell glycoprotein. Four anti-K Mabs precipitated the expected 93kD protein and a dimeric form under non-reducing conditions.
Janvier
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Secteur d'Hémobiologie-Transfusion de Paris-Est, Hôpital St-Louis, Paris, France.
Veaux
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Benbunan
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D000911:Antibodies, Monoclonal; D001789:Blood Group Antigens / Q000276:immunology*; D004912:Erythrocytes / Q000276:immunology*; D006023:Glycoproteins / Q000276:immunology; D006801:Humans; D007626:Kell Blood-Group System / Q000276:immunology; D008188:Lutheran Blood-Group System / Q000276:immunology
D000911:Antibodies, Monoclonal; D001789:Blood Group Antigens; D006023:Glycoproteins; D007626:Kell Blood-Group System; D008188:Lutheran Blood-Group System