Nosocomial Neisseria meningitidis: molecular analysis of a clinical problem.
Over a 1-week period, Neisseria meningitidis serogroup B was recovered from two patients in the intensive-care unit (ICU). A cross-infection was presumed when one patient developed invasive meningococcal disease and another patient was found to be colonized. Investigation by molecular typing showed that these cases were not related, demonstrating the value of molecular typing when investigating potential cross-infections in a closed environment such as the ICU.
Louie
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M
Department of Microbiology-B121, Sunnybrook Health Science Centre, Toronto, Ontario, Canada.
Simor
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Rachlis
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Louie
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D003428:Cross Infection / Q000175:diagnosis / Q000382:microbiology*; D004269:DNA, Bacterial / Q000145:classification; D016521:Electrophoresis, Gel, Pulsed-Field; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008589:Meningococcal Infections / Q000382:microbiology / Q000635:transmission*; D008875:Middle Aged; D009345:Neisseria meningitidis / Q000145:classification*; D016133:Polymerase Chain Reaction; D012703:Serotyping
D004269:DNA, Bacterial