title: Long-term potentiation and long-term depression in the lateral septum in spatial working and reference memory.
abstract: We report two experiments conducted on a radial arm maze in the mouse showing that training could either enhance or reduce the efficacy of the fimbria-lateral septal synapses. It is suggested that the direction of change is determined by the kind of situation the animal is faced with (ie trial-dependent, respectively).
authors.affiliation: Laboratoire de Neurosciences Comportementales & Cognitives, CNRS URA 339, Université de Bordeaux, Talence, France.
authors.forename: R
authors.initials: R
authors.lastname: Jaffard
authors.forename: R M
authors.initials: RM
authors.lastname: Vouimba
authors.forename: A
authors.initials: A
authors.lastname: Marighetto
authors.forename: R
authors.initials: R
authors.lastname: Garcia
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D005071:Evoked Potentials; D006624:Hippocampus / Q000502:physiology*; D007395:Interneurons / Q000502:physiology; D017774:Long-Term Potentiation / Q000502:physiology*; D018782:Maze Learning / Q000502:physiology*; D008568:Memory / Q000502:physiology*; D051379:Mice; D008810:Mice, Inbred C57BL; D009473:Neuronal Plasticity / Q000502:physiology*; D013028:Space Perception; D013569:Synapses / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology