[Molecular-genetic screening of Siberian swine populations: local breeds are not burdened with a genetic load of malignant hyperthermia].
By molecular genetic screening of porcine DNA, including direct detection of point mutation, Kemerovskaya and Skorospelaya meat breeds were shown to be virtually free of the genetic load of the mutation causing porcine stress syndrome. Peculiarities in dynamics of the mutant allele and genotype frequencies of the RYR1 locus were revealed.
Kniazev
S P
SP
Humbold University, Berlin, Germany.
Khardge
T
T
Zhuchaev
K V
KV
D000483:Alleles; D000818:Animals; D002874:Chromosome Mapping; D005260:Female; D005787:Gene Frequency; D005820:Genetic Testing / Q000379:methods*; D005828:Genetics, Population; D005838:Genotype; D008297:Male; D008305:Malignant Hyperthermia / Q000235:genetics*; D017354:Point Mutation; D013552:Swine / Q000235:genetics*
Molekuliarno-geneticheskiĭ skrining sibirskikh populiatsiĭ svineĭ: mestnye porody ne otiagoshcheny nasledstvennym gruzom zlokachestvennoĭ gipertermii.