title: Characterization of large linear plasmids in mycobacteria.
abstract: Linear plasmids were found in Mycobacterium xenopi, M. branderi, and M. celatum. These elements represented a wide size range (from 20 to 320 kb), had Streptomyces-like terminal structures, and defined five hybridization groups. Cross-hybridization and common restriction fragment length polymorphism patterns of plasmids from the different species suggest either genetic exchange or a common ancestry of the species.
authors.affiliation: Laboratoire de Référence des Mycobactéries, Institut Pasteur, Paris,France.
authors.forename: M
authors.initials: M
authors.lastname: Picardeau
authors.forename: V
authors.initials: V
authors.lastname: Vincent
mesh_terms: D015139:Blotting, Southern; D004264:DNA Topoisomerases, Type I; D016521:Electrophoresis, Gel, Pulsed-Field / Q000379:methods; D005090:Exodeoxyribonucleases; D008970:Molecular Weight; D009161:Mycobacterium / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D010957:Plasmids / Q000032:analysis* / Q000737:chemistry / Q000235:genetics; D012150:Polymorphism, Restriction Fragment Length
chemical_list: D005090:Exodeoxyribonucleases; C020133:exodeoxyribonuclease III; D004264:DNA Topoisomerases, Type I