title: [Relationship between cytochemical activity of leukocytes and autorosette formation phenomenon and its clinical significance in patients with leptospirosis].
abstract: The content of autorosettes in the peripheral blood forming from red cells round neutrophils and monocytes was found increased during the acute period of icterohemorrhagic leptospirosis. Autorosette-forming cells are characterized by a high activity of alkaline and acid phosphatases and low NBT-test values. The content of autorosettes directly correlates with the disease severity, bilirubin level, and presence of anemia. Assessment of autorosette-forming cells in patients with leptospirosis may be used as an additional test for evaluating the severity of intoxication, disease course, and for predicting the complications and disease outcome.
authors.forename: M G
authors.initials: MG
authors.lastname: Subich
authors.forename: M G
authors.initials: MG
authors.lastname: Avdeeva
authors.forename: D L
authors.initials: DL
authors.lastname: Moĭsova
mesh_terms: D000135:Acid Phosphatase / Q000097:blood; D000293:Adolescent; D000328:Adult; D000368:Aged; D000469:Alkaline Phosphatase / Q000097:blood; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007962:Leukocytes / Q000276:immunology* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D012397:Rosette Formation; D014895:Weil Disease / Q000175:diagnosis / Q000276:immunology* / Q000378:metabolism
chemical_list: D000469:Alkaline Phosphatase; D000135:Acid Phosphatase
vernacular_title: Vzaimosviaz' tsitokhimicheskoĭ aktivnosti leĭkotsitov s fenomenom autorozetkoobrazovaniia i ego klinicheskoe znachenie u bol'nykh leptospirozom.