[The ATP content of the neutrophils and whole blood in the inhabitants of regions in the Altai Territory subjected to nuclear testing exposure].
The bioluminescent method was used in the studies of the influence of ionizing irradiation and/or xenobiotics on the content of ATP in RBC and neutrophils of rats, and in whole blood and neutrophils of 80 examined women of Altai Region exposed to ionizing radiation during a series of nuclear tests in Semipalatinsk in 1949-1965. Deviations from the normal ATP content were measured with due to account of the natural variability of a given metabolite. For rats, deviations from the content of ATP in erythrocytes were short-term, those in neutrophils were long-term. For people, a statistically significant increase in the content of ATP in neutrophils as compared to the control was observed. A non-linear correlation between the content of ATP in neutrophils and the calculated dose of radiation was observed. An increase in the ATP content in whole blood, with regard to the control, was not statistically significant for all groups of examined persons.
Frundzhian
V G
VG
Romanova
N A
NA
Dement'eva
E I
EI
Brovko
L Iu
LIu
Ugarova
N N
NN
Novikov
K N
KN
Brusovanik
V I
VI
Kobialko
V O
VO
Meshkov
N A
NA
D000255:Adenosine Triphosphate / Q000097:blood / Q000528:radiation effects*; D000818:Animals; D004912:Erythrocytes / Q000187:drug effects / Q000528:radiation effects; D005260:Female; D005720:Gamma Rays; D006801:Humans; D008297:Male; D009504:Neutrophils / Q000187:drug effects / Q000528:radiation effects*; D009689:Nuclear Warfare; D011847:Radioactive Fallout / Q000009:adverse effects*; D051381:Rats; D017208:Rats, Wistar; D012424:Rural Population; D012800:Siberia; D013997:Time Factors; D015262:Xenobiotics / Q000494:pharmacology
D011847:Radioactive Fallout; D015262:Xenobiotics; D000255:Adenosine Triphosphate
Soderzhanie ATF v neĭtrofilakh i tsel'noĭ krovi u zhiteleĭ raĭonov Altaĭskogo kraia, podvergshikhsia vozdeĭstviiu iadernykh ispytaniĭ.