[Oncologic surgery of malignancies in childhood. Effect of adjuvant/neoadjuvant methods].
Pre- and/or postoperative chemotherapy is highly effective in the treatment of pediatric malignancies and has modified surgical strategies significantly. (1) In childhood abdominal Non-Hodgkin-Lymphomas early chemotherapy has a definite priority over extended excisions. (2) In hepatoblastomas, radical excision is essential for effecting a cure. However, in the case of an advanced tumor, it is wise to start treatment with chemotherapy and then to perform surgery. (3) Pre-operative chemotherapy in Wilms' tumors effects a "down staging", which allows therapy reduction and omission of postoperative radiotherapy in the majority of cases.
Mildenberger
H
H
Kinderchirurgische Abteilung, Medizinische Hochschule Hannover.
D017024:Chemotherapy, Adjuvant; D002648:Child; D003131:Combined Modality Therapy; D018197:Hepatoblastoma / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D006801:Humans; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D008113:Liver Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D009369:Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D011379:Prognosis; D009396:Wilms Tumor / Q000188:drug therapy / Q000473:pathology / Q000601:surgery
Onkologische Chirurgie bei Malignomen im Kindesalter. Einfluss adjuvanter/neoadjuvanter Methoden.