Possibilities of gene therapies for cancer.
Cancer is an acquired disease in which it is possible to identify a variety of abnormalities at a genetic level. This holds a promise that genetic manipulation of tumour cells will lead to novel therapies. As yet these approaches are constrained by available methods for obtaining gene transfer and subsequent genetic control. However, a number of strategies are already reaching the clinic, including attempts at immunotherapy, prodrug activation and improving host defence against conventional chemotherapy. Further clinical opportunities will occur with improved vector development.
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D000818:Animals; D015316:Genetic Therapy / Q000145:classification / Q000379:methods* / Q000639:trends; D006801:Humans; D009369:Neoplasms / Q000235:genetics* / Q000628:therapy*; D009374:Neoplasms, Experimental / Q000235:genetics / Q000628:therapy