[Reduction of alcohol consumption and its effect on Na(+)-K(+)-ATPase activity of red blood cell membrane].
Fifty-four untreated, mildly hypertensive men who were civil servants and were aged 30-59 years reduced their alcohol consumption as much as possible for three weeks. Then blood pressure and serum gamma GTP decreased significantly, but Na(+)-K(+)-ATPase activity of the red blood cell membrane did not change significantly. The enzyme activity in twenty subjects (45.5% of total subjects) increased and that in twenty-four subjects (54.5%) decreased or was unchanged. No significant relationship between the ratio of the change of Na(+)-K(+)-ATPase activity and that of blood pressure or serum gamma GTP was observed.
Kurosawa
Y
Y
Department of Community Medicine, Toyama Medical and Pharmaceutical University, Japan.
Naruse
Y
Y
Kagamimori
S
S
Mikawa
K
K
Ueshima
H
H
D000328:Adult; D000428:Alcohol Drinking; D004910:Erythrocyte Membrane / Q000201:enzymology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D000254:Sodium-Potassium-Exchanging ATPase / Q000097:blood*; D005723:gamma-Glutamyltransferase / Q000097:blood
D005723:gamma-Glutamyltransferase; D000254:Sodium-Potassium-Exchanging ATPase