title: Increased levels of proteoglycan fragments and stromelysin in hip joint fluid in Legg-Calvé-Perthes disease.
abstract: The concentrations of proteoglycan fragments and stromelysin were analyzed in joint aspirates in 19 children with Legg-Calvé-Perthes disease. We found increased levels of proteoglycan fragments and stromelysin consistent with the presence of synovitis, an important clinical and possibly also prognostic factor in these children.
authors.affiliation: Department of Orthopedics, University Hospital of Lund, Sweden.
authors.forename: G
authors.initials: G
authors.lastname: Eckerwall
authors.forename: L S
authors.initials: LS
authors.lastname: Lohmander
authors.forename: H
authors.initials: H
authors.lastname: Wingstrand
mesh_terms: D002648:Child; D002675:Child, Preschool; D005260:Female; D006621:Hip Joint / Q000378:metabolism; D006801:Humans; D007873:Legg-Calve-Perthes Disease / Q000145:classification / Q000378:metabolism*; D008297:Male; D019278:Matrix Metalloproteinase 3 / Q000032:analysis*; D011509:Proteoglycans / Q000032:analysis*; D013582:Synovial Fluid / Q000737:chemistry*
chemical_list: D011509:Proteoglycans; D019278:Matrix Metalloproteinase 3