title: [High-dose methylprednisolone pulse therapy for respiratory failure after open heart surgery].
abstract: After open-heart surgery, we sometime experience a patient whose respiratory function worsens extremely, though a heart function is improved. We experienced four such cases and treated with high-dose methylprednisolone. Then, we recognized that the respiratory function was improved at all cases. However, one case deteriorated again regarding the respiratory function, as a start of the treatment was delayed. There is a possibility that host resistance to infection is decreased by administration of corticosteroids. Therefore, we hesitate to treat with corticosteroids. Concerning respiratory failure after open heart surgery, however, we think that a respiratory function of a patient is improved if high-dose methylprednisolone pulse therapy is started in early stage.
authors.affiliation: Department of Thoracic Surgery, Yokohama Municipal Citizen's Hospital, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kurata
authors.forename: I
authors.initials: I
authors.lastname: Yamazaki
authors.forename: M
authors.initials: M
authors.lastname: Ishii
authors.forename: Y
authors.initials: Y
authors.lastname: Yano
authors.forename: M
authors.initials: M
authors.lastname: Kase
authors.forename: I
authors.initials: I
authors.lastname: Tomiyama
mesh_terms: D000368:Aged; D000787:Angina Pectoris / Q000601:surgery; D001026:Coronary Artery Bypass; D004334:Drug Administration Schedule; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage*; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy*; D012131:Respiratory Insufficiency / Q000188:drug therapy*
chemical_list: D008775:Methylprednisolone