Single cell analyses of cytokine production.
Subsets of T lymphocytes have been defined by their secretion of polarized patterns of cytokines. Type 1 and Type 2 subsets have been characterized in a variety of model systems both in vivo and in vitro and are a useful framework for studying immune responses. Recent technical advances have made it possible to analyze cytokine production by these populations at the level of individual cells.
Carter
L L
LL
Trudeau Institute, New York, NY 12983, USA.
Swain
S L
SL
D016207:Cytokines / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D017403:In Situ Hybridization; D016133:Polymerase Chain Reaction; D013601:T-Lymphocytes / Q000166:cytology* / Q000276:immunology / Q000378:metabolism*; D018417:Th1 Cells / Q000378:metabolism; D018418:Th2 Cells / Q000378:metabolism
D016207:Cytokines