Soluble CD30 serum antigen in Kawasaki disease.
Very high levels of sCD30, a glycoprotein surface antigen expressed by T lymphocytes and other mononuclear cells of the immune system, were found in serum samples from 10 children with typical Kawasaki disease (KD), but not in blood specimens from a vast cohort of paediatric control subjects. These data strongly support an involvement of CD30 T cells in the immune processes which take place at the level of lymphoid organs during the acute phase of KD.
Vagliasindi
C
C
Department of Paediatrics and Internal Medicine and Oncological Sciences, Perugia University Medical School, Italy.
Spinozzi
F
F
Sensi
L
L
Radicioni
M
M
De Rosa
O
O
Solinas
L
L
Vaccaro
R
R
Bertotto
A
A
D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007223:Infant; D017730:Ki-1 Antigen / Q000097:blood* / Q000276:immunology*; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D017730:Ki-1 Antigen