Lobular carcinoma of the male breast associated with the use of cimetidine.
A case of carcinoma in the breast of a male patient with a chronic gastric ulcer is described. The patient had received cimetidine for 17 years. Histological examination of an excisional biopsy showed lobular in situ and infiltrating carcinoma. In our review of the English literature, this is the 18th case of lobular carcinoma of the male breast to be reported; it is also the first report of lobular carcinoma associated with the use of cimetidine, and the second in a man with documentation of genotype.
San Miguel
P
P
Department of Pathology, Hospital Ramon y Cajal, Madrid, Spain.
Sancho
M
M
Enriquez
J L
JL
Fernandez
J
J
Gonzalez-Palacios
F
F
D000897:Anti-Ulcer Agents / Q000009:adverse effects* / Q000627:therapeutic use; D018567:Breast Neoplasms, Male / Q000139:chemically induced* / Q000473:pathology; D018275:Carcinoma, Lobular / Q000139:chemically induced* / Q000473:pathology; D002908:Chronic Disease; D002927:Cimetidine / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D013276:Stomach Ulcer / Q000188:drug therapy; D013997:Time Factors
D000897:Anti-Ulcer Agents; D002927:Cimetidine