Primitive neuroectodermal tumor in a child with tuberous sclerosis.
The case of a 13-year-old boy with tuberous sclerosis and primitive neuroectodermal tumor of bone is presented. A pathogenetic association between these two entities is postulated, the unifying underlying mechanism being a maldevelopment of the neural crest, or neurocristopathy.
Hindman
B W
BW
Department of Radiology, Loma Linda University School of Medicine, CA 92354, USA.
Gill
H K
HK
Zuppan
C W
CW
D000293:Adolescent; D001859:Bone Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009432:Neural Crest / Q000473:pathology; D018242:Neuroectodermal Tumors, Primitive / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging; D013977:Tibia / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014402:Tuberous Sclerosis / Q000150:complications*