Erythromelalgia following influenza vaccine in a child.
Erythromelalgia is a rare disease characterised by palmar and plantar erythema, burning pain and local increases in temperature. Erythromelalgia in adults most commonly appears secondary to myeloproliferative disorders, essential thrombocytosis and polycythemia vera; however, in children primary forms predominate. Erythromelalgia in children is characterised by a chronic relapsing course, usually refractory to treatment. We describe a case of erythromelalgia which developed in a 4.5 year old girl following influenza vaccination. Low dose aspirin, carbamazepine and propranolol induced a rapid resolution of the syndrome.
Confino
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Paediatric Department B, Chaim Sheba Medical Centre, Tel Hashomer, Israel.
Passwell
J H
JH
Padeh
S
S
D001241:Aspirin / Q000627:therapeutic use; D002220:Carbamazepine / Q000627:therapeutic use; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D004916:Erythromelalgia / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D007252:Influenza Vaccines / Q000009:adverse effects*; D011433:Propranolol / Q000627:therapeutic use
D007252:Influenza Vaccines; D002220:Carbamazepine; D011433:Propranolol; D001241:Aspirin