Cervical cancer and cytomegalovirus.
Paraffin embedded sections from 34 cases of cervical cancer in Uganda were examined for the presence of cytomegalovirus (CMV) using immunohistochemistry. CMV was detected in five of the 34 cases. In all cases, the reactivity was confined to the cervical epithelial tissue. These results provide further evidence for an association between CMV and cervical cancer and show that CMV may be readily detected in archival materials. It also suggests that cervical cancer may be associated with immune deficiency.
Odida
M
M
Department of Pathology, Makerere University Medical School, Kampala, Uganda.
Schmauz
R
R
D016022:Case-Control Studies; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D002583:Uterine Cervical Neoplasms / Q000821:virology*