Azathioprine-induced skin peeling syndrome.
A case of azathioprine-induced skin peeling is reported. Tiny superficial blisters and peeling predominated in flexures. Keratinosomes were severely defective and corneocytes contained intracytoplasmic desmosomes.
Hermanns-Lê
T
T
Department of Dermatopathology, University of Liège, Belgium.
Piérard
G E
GE
D001379:Azathioprine / Q000009:adverse effects*; D003593:Cytoplasm / Q000648:ultrastructure; D003896:Desmosomes / Q000648:ultrastructure; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D015603:Keratinocytes / Q000473:pathology; D007642:Keratosis / Q000473:pathology; D016030:Kidney Transplantation; D008875:Middle Aged; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000473:pathology
D007166:Immunosuppressive Agents; D001379:Azathioprine