Lamotrigine for pain with hyperalgesia.
Pain associated with hyperalgesia of the affected area occurs in a number of conditions. We describe our experience of using the drug Lamotrigine in the management of this pain in 3 individuals with Phantom limb pain and stump hypersensitivity Post herpetic neuralgia and causalgia respectively. We discuss the mechanism of action of the drug and why possibly it renders it effective in this form of pain.
Harbison
J
J
Department of Medicine for the Elderly, St Vincent's Hospital, Elm Park, Dublin.
Dennehy
F
F
Keating
D
D
D000368:Aged; D000369:Aged, 80 and over; D000927:Anticonvulsants / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006930:Hyperalgesia / Q000188:drug therapy*; D000077213:Lamotrigine; D008297:Male; D010146:Pain / Q000188:drug therapy*; D014227:Triazines / Q000627:therapeutic use*
D000927:Anticonvulsants; D014227:Triazines; D000077213:Lamotrigine