Campylobacter-host cell interactions.
The enteric pathogens Campylobacter jejuni and Campylobacter coli are a major cause of infectious diarrhoea. Their ability to adhere to human epithelial cells is ubiquitous and their propensity to invade cells is also well documented and requires motility and de novo protein synthesis, as well as several host factors. The molecular basis of the interaction between campylobacters and host cells is only beginning to be elucidate. The characteristics of this interaction promise to be interesting and may provide new insights into host-pathogen interactions in other enteric diseases.
Wooldridge
K G
KG
Dept of Genetics, University of Leicester, UK.
Ketley
J M
JM
D002169:Campylobacter Infections / Q000503:physiopathology; D017000:Campylobacter coli / Q000276:immunology* / Q000472:pathogenicity; D016123:Campylobacter jejuni / Q000276:immunology* / Q000472:pathogenicity; D002460:Cell Line; D004847:Epithelial Cells; D006801:Humans; D008264:Macrophages / Q000276:immunology; D009000:Monocytes / Q000276:immunology; D009504:Neutrophils / Q000276:immunology