[The effect of alphacalcidol on calcium and phosphate metabolism in patients treated with hemodialysis].
The purpose of these studies was to assess the effect of 6 month calcidol treatment on Ca and PO4 metabolism in haemodialyzed patients. During 3 and 6 month on alpha calcidol therapy, there was significant increase of total and ionized Ca (p < 0.05; p < 0.01 respectively). After 6 months on alpha calcidol therapy there was significant decrease of alkaline phosphatase level (p < 0.05) and increase in bone density (up to 82%, p < 0.05). The study has shown that appropriate use of alpha calcidol could be effective in treatment of Ca and PO4 disbalance in haemodialyzed patients.
Veljković
S
S
Institute of Nephrology and Haemodialysis, Medical School, Nish.
Raicević
R
R
Cukaranović
R
R
Ralenković
S
S
Stojanović
M
M
Kostić
S
S
Djordjević
V
V
Radenković
M
M
D000328:Adult; D000368:Aged; D000469:Alkaline Phosphatase / Q000378:metabolism; D002118:Calcium / Q000378:metabolism*; D005260:Female; D006801:Humans; D006887:Hydroxycholecalciferols / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D010758:Phosphorus / Q000378:metabolism*; D006435:Renal Dialysis
D006887:Hydroxycholecalciferols; D010758:Phosphorus; D000469:Alkaline Phosphatase; D002118:Calcium; C008088:alfacalcidol
Dejstvo sestomesecne terapije alfakalcidolom na metabolizam kalcijuma i fosfata kod bolesnika lecenih ponavljanihm hemodijalizama.