HLA DR and DQ RFLP analysis in Crohn's disease.
A study of 109 Swedish patients and 85 healthy Swedish controls with Crohn's disease (CD) by HLA class II RFLP genotyping was carried out. There was no significant association for any single DR or DQ specificity or phenotypic combination of DR and/or DQ specificities among our study group of Caucasian extraction.
Wassmuth
R
R
Department of Medicine III, University of Erlangen-Nürnberg, Germany.
Eastman
S
S
Kockum
I
I
Holmberg
E
E
Starck
M
M
Lindhagen
T
T
Kalden
J R
JR
Lernmark
A
A
Sundkvist
G
G
Lindgren
S
S
D001483:Base Sequence; D016022:Case-Control Studies; D003424:Crohn Disease / Q000235:genetics* / Q000276:immunology*; D005787:Gene Frequency; D005838:Genotype; D006683:HLA-DQ Antigens / Q000235:genetics*; D006684:HLA-DR Antigens / Q000235:genetics*; D006801:Humans; D015345:Oligonucleotide Probes / Q000235:genetics; D010641:Phenotype; D012150:Polymorphism, Restriction Fragment Length; D013548:Sweden
D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens; D015345:Oligonucleotide Probes