title: Acute renal failure due to rhabdomyolysis in diabetic patients.
abstract: We report a 32-year-old Black man, admitted to the ICU with coma and severe metabolic disturbances due to diabetic ketoacidosis. During the admission, rhabdomyolysis and acute renal failure (ARF) were diagnosed. After metabolic control and gradual decrease of creatine kinase levels, he presented a progressive improvement of renal function. We emphasize nontraumatic rhabdomyolysis as a poorly recognized pathogenetic factor for ARF in diabetic ketoacidosis and suggest that a better understanding of its mechanisms and an early application of protective measures is necessary.
authors.affiliation: Intensive Care Unit, Hospital Municpal Artur Ribeiro de Saboya, São Paulo, Brazil.
authors.forename: E M
authors.initials: EM
authors.lastname: Higa
authors.forename: S A
authors.initials: SA
authors.lastname: Dib
authors.forename: J R
authors.initials: JR
authors.lastname: Martins
authors.forename: L
authors.initials: L
authors.lastname: Campos
authors.forename: E
authors.initials: E
authors.lastname: Homsi
mesh_terms: D058186:Acute Kidney Injury / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000188:drug therapy; D003926:Diabetic Coma / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D003937:Diagnosis, Differential; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D007677:Kidney Function Tests; D008297:Male; D006435:Renal Dialysis; D012206:Rhabdomyolysis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy
chemical_list: D007328:Insulin