title: Endophthalmitis and orbital cellulitis after radial keratotomy.
abstract: OBJECTIVE
  To report the findings concerning three patients with endophthalmitis and one with panophthalmitis and orbital cellulitis radial keratotomy surgery.
  
  
  METHODS
  One man referred with panophthalmitis and orbital cellulitis and three women referred with endophthalmitis were treated.
  
  
  RESULTS
  After radial keratotomy surgery, during which no microperforation or macroperforation had been reported, a severe Pseudomonas panophthalmitis and orbital cellulitis developed in the man. All vision was lost in that eye. Staphylococcus epidermidis endophthalmitis developed in one woman, Streptococcus pneumoniae endophthalmitis in the second woman and Pseudomonas endophthalmitis in the third woman, after undergoing radial keratotomy procedures during which microperforations occurred. In the latter patient, bilateral simultaneous surgery was performed, but only one eye became infected. The latter two infections resulted in light perception and hand motion vision respectively. In three cases, an initial keratitis was located in the inferior cornea.
  
  
  CONCLUSIONS
  Severe bacterial endophthalmitis can occur after radial keratotomy surgery, even in the absence of microperforation during the procedure. Any evidence of postoperative keratitis must be regarded seriously and treated aggressively. Despite use of this approach, the effect on final visual acuity can be devastating.
authors.affiliation: Department of Ophthalmology, University of Southern California School of Medicine, Los Angeles, USA.
authors.forename: S D
authors.initials: SD
authors.lastname: McLeod
authors.forename: C W
authors.initials: CW
authors.lastname: Flowers
authors.forename: P F
authors.initials: PF
authors.lastname: Lopez
authors.forename: J
authors.initials: J
authors.lastname: Marx
authors.forename: P J
authors.initials: PJ
authors.lastname: McDonnell
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002481:Cellulitis / Q000188:drug therapy / Q000382:microbiology*; D009877:Endophthalmitis / Q000188:drug therapy / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D007646:Keratotomy, Radial / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009916:Orbital Diseases / Q000188:drug therapy / Q000382:microbiology*; D010202:Panophthalmitis / Q000188:drug therapy / Q000382:microbiology; D011552:Pseudomonas Infections / Q000188:drug therapy / Q000209:etiology*; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000209:etiology*; D013212:Staphylococcus epidermidis / Q000302:isolation & purification; D013290:Streptococcal Infections / Q000188:drug therapy / Q000209:etiology*; D013296:Streptococcus pneumoniae / Q000302:isolation & purification; D014822:Vitreous Body / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents