title: In-vivo measurements of blood flow velocity profiles in canine ilio-femoral anastomotic bypass grafts.
abstract: In-vivo velocity profiles were recorded with a 20 MHz 80-channel pulsed Doppler ultrasound velocimeter in canine end-to-side ilio-femoral anastomotic grafts. The geometries were obtained from casts of the anastomotic region, and flow rates were measured with electromagnetic flow probes. Three cases reported here include a "standard" geometry, which was similar to previously studied in vitro models, a stenosed geometry, and a case with below average flow rate. Observed flow features include separation at the hood and toe, movement of the floor stagnation point, and skewed profiles in the proximal outflow segment. Out-of-plane curvature and lateral displacement of the anastomosis inlet appear to have a strong effect on the flow fields. In addition, compliance affects the instantaneous flow rates within the proximal and distal branches.
authors.affiliation: Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21218, USA.
authors.forename: S A
authors.initials: SA
authors.lastname: Jones
authors.forename: D P
authors.initials: DP
authors.lastname: Giddens
authors.forename: F
authors.initials: F
authors.lastname: Loth
authors.forename: C K
authors.initials: CK
authors.lastname: Zarins
authors.forename: F
authors.initials: F
authors.lastname: Kajiya
authors.forename: I
authors.initials: I
authors.lastname: Morita
authors.forename: O
authors.initials: O
authors.lastname: Hiramatsu
authors.forename: Y
authors.initials: Y
authors.lastname: Ogasawara
authors.forename: K
authors.initials: K
authors.lastname: Tsujioka
mesh_terms: D000714:Anastomosis, Surgical; D000818:Animals; D001783:Blood Flow Velocity; D003187:Compliance; D003251:Constriction, Pathologic / Q000000981:diagnostic imaging; D004195:Disease Models, Animal; D004285:Dogs; D005263:Femoral Artery / Q000000981:diagnostic imaging* / Q000601:surgery; D005268:Femoral Vein / Q000637:transplantation*; D007083:Iliac Artery / Q000000981:diagnostic imaging* / Q000601:surgery; D007601:Jugular Veins / Q000637:transplantation*; D008955:Models, Cardiovascular; D014463:Ultrasonography; D014654:Vascular Patency