title: Apnea prolongation via short-term inhibition.
abstract: Central apneas during sleep are frequently of longer duration than predicted and persist despite high levels of chemical stimuli. We provide evidence that suggests that this apnea prolongation represents a central inertia in the control system mediated by reciprocal inhibition of inspiration.
authors.affiliation: John Rankin Laboratory of Pulmonary Medicine, Department of Preventive Medicine, University of Wisconsin-Madison 53706, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Dempsey
authors.forename: A M
authors.initials: AM
authors.lastname: Leevers
authors.forename: C R
authors.initials: CR
authors.lastname: Wilson
authors.forename: C A
authors.initials: CA
authors.lastname: Harms
authors.forename: C A
authors.initials: CA
authors.lastname: Smith
mesh_terms: D000818:Animals; D001049:Apnea; D004285:Dogs; D004576:Electromyography; D006801:Humans; D008568:Memory; D012121:Respiration, Artificial; D012895:Sleep, REM; D013997:Time Factors; D015919:Ventilators, Negative-Pressure; D014851:Wakefulness