Autism in Down's syndrome: family history correlates.
Although the association of autism with Down's syndrome is said to be uncommon, several reports have described the co-occurrence of the two disorders. This report describes three additional cases of Down's syndrome with autism. In all the patients, a history suggestive of the broader phenotype of autism was obtained in parents. This suggests that familial factors specific to autism may play an important role even when autism complicates a known medical condition such as Down's syndrome.
Ghaziuddin
M
M
Taubman Centre, University of Michigan Medical Centre, Ann Arbor 48109-0390, USA.
D000293:Adolescent; D000328:Adult; D001321:Autistic Disorder / Q000150:complications* / Q000235:genetics*; D004314:Down Syndrome / Q000150:complications*; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000150:complications; D008297:Male; D010641:Phenotype