[Wilson's disease].
Wilson's disease is a rare inherited metabolic disorder usually characterized by liver and/or neurological degeneration. Unlike most genetically transmitted diseases, it rapidly responds to pharmacological treatment in case of early diagnosis and treatment. Often, however, as this disease presents with aspecific symptoms, patients are wrongly diagnosed as psychiatric cases or as having generic chronic liver disease and the true cause of symptoms is only discovered at a much later stage. The authors give a detailed review of the literature with the aim of presenting the most recent research on the main aspects of this disease and offering a practical and simple approach to early diagnosis.
Bonfissuto
G
G
Cattedra di Medicina Interna, Università, Palermo.
Magliarisi
C
C
Soresi
M
M
Bascone
F
F
Costanza
G
G
Carroccio
A
A
Montalto
G
G
D000293:Adolescent; D000328:Adult; D002614:Chelating Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006527:Hepatolenticular Degeneration / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D010396:Penicillamine / Q000627:therapeutic use; D014266:Trientine / Q000627:therapeutic use; D015032:Zinc / Q000627:therapeutic use
D002614:Chelating Agents; D010396:Penicillamine; D015032:Zinc; D014266:Trientine
Morbo di Wilson.