title: Cytotoxic triterpenes from Cleome africana.
abstract: Eighteen dammarane-type triterpenes were obtained from the whole plant of Cleome africana by means of cytotoxic bioassay-directed fractionation. Twelve of them were novel compounds whose structures were elucidated by various spectroscopic methods.
authors.affiliation: Katakura Industry Co., Ltd., Sayama, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Nagaya
authors.forename: Y
authors.initials: Y
authors.lastname: Tobita
authors.forename: T
authors.initials: T
authors.lastname: Nagae
authors.forename: H
authors.initials: H
authors.lastname: Itokawa
authors.forename: K
authors.initials: K
authors.lastname: Takeya
authors.forename: A F
authors.initials: AF
authors.lastname: Halim
authors.forename: O B
authors.initials: OB
authors.lastname: Abdel-Halim
mesh_terms: D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D017691:Caribbean Region; D002470:Cell Survival / Q000187:drug effects*; D007941:Leukemia P388; D008519:Medicine, Traditional; D051379:Mice; D015394:Molecular Structure; D010946:Plants, Medicinal; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D014407:Tumor Cells, Cultured
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D014315:Triterpenes