[Mixed-type pancreatoblastoma. Report of a clinical case].
Pancreatoblastoma is a very rare tumor of the pancreas, affecting children in the first decade of life. Ultrasound and CT scan may be useful but pre-operative diagnosis is often quite difficult. High level of seric alpha-fetoprotein could be suggestive of pancreatoblastoma. The definitive diagnosis is however made by histologists when an organoid structure, well encapsulated, consisting of acinar cells with zymogen-like granules and squamoid corpuscle is demonstrated, sometimes associated with mesenchymal tissue (mixed-type pancreatoblastoma). Immunohistochemical studies may help in differentiating pancreatoblastoma from papillary cystic tumors, acinar cell carcinomas and endocrine pancreatic tumors of the pancreas. We report a case of mixed-type pancreatoblastoma in a 12-year-old female patient, located in the head of the pancreas. The treatment has been surgical, consisting of a duodeno-cephalo-pancreasectomy. Neither radiotherapy nor chemotherapy has been performed. The patient is alive, without recurrence, four months after the operation. Diagnostic, therapeutic and prognostic aspects are discussed.
Latteri
S
S
Dipartimento di Chirurgia, Università degli Studi, Catania.
Russo
G
G
Vecchio
R
R
Meli
G
G
Latteri
F
F
D002648:Child; D005260:Female; D006801:Humans; D010190:Pancreatic Neoplasms / Q000473:pathology*
Pancreatoblastoma di tipo misto. Presentazione di un caso clinico.