title: [A two-year asymptomatic case with postoperative lung metastasis of sigmoid colon cancer responding to sequential methotrexate and 5-fluorouracil].
abstract: In a 76-year-old female outpatient, recurrent lung metastasis after sigmoidectomy due to sigmoid colon cancer responded to chemotherapy of sequential methotrexate and 5-fluorouracil. A total of 46 courses of this chemotherapy in two years suppressed the rapid growth of the metastasis. During this therapy, the patient's condition was good, with no experience of nausea or leukopenia. This case suggests that chemotherapy of sequential methotrexate and 5-fluorouracil gave a person with lung metastasis of sigmoid colon cancer a good quality of life during a long time.
authors.affiliation: Dept. of Surgery, Nishijin Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Kitao
authors.forename: R
authors.initials: R
authors.lastname: Yasuoka
authors.forename: K
authors.initials: K
authors.lastname: Yamamoto
authors.forename: T
authors.initials: T
authors.lastname: Miyagaki
authors.forename: T
authors.initials: T
authors.lastname: Nakamura
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000556:secondary* / Q000601:surgery; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D012809:Colon, Sigmoid / Q000601:surgery*; D004334:Drug Administration Schedule; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008727:Methotrexate / Q000008:administration & dosage; D011788:Quality of Life; D012811:Sigmoid Neoplasms / Q000188:drug therapy* / Q000473:pathology* / Q000601:surgery
chemical_list: D005472:Fluorouracil; D008727:Methotrexate