title: Histamine up-regulates the generation of nitric oxide, and nitric oxide down-regulates the release of histamine in cardiovascular preparations.
authors.affiliation: Department of Preclinical and Clinical Pharmacology, University of Florence, Italy.
authors.forename: P F
authors.initials: PF
authors.lastname: Mannaioni
authors.forename: M G
authors.initials: MG
authors.lastname: Bello
authors.forename: M G
authors.initials: MG
authors.lastname: Di Bello
authors.forename: W
authors.initials: W
authors.lastname: Schunack
authors.forename: E
authors.initials: E
authors.lastname: Masini
mesh_terms: D000818:Animals; D002320:Cardiovascular Physiological Phenomena; D002319:Cardiovascular System / Q000187:drug effects*; D002417:Cattle; D002478:Cells, Cultured; D003326:Coronary Circulation / Q000187:drug effects; D017259:Dimaprit / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006168:Guinea Pigs; D006632:Histamine / Q000494:pharmacology*; D017442:Histamine Agonists / Q000494:pharmacology; D006636:Histamine Release / Q000187:drug effects*; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology; D009569:Nitric Oxide / Q000378:metabolism* / Q000494:pharmacology*; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors; D019323:omega-N-Methylarginine / Q000494:pharmacology
chemical_list: D004791:Enzyme Inhibitors; D017442:Histamine Agonists; D019323:omega-N-Methylarginine; D009569:Nitric Oxide; D006632:Histamine; D019001:Nitric Oxide Synthase; D017259:Dimaprit