title: [Effect of dietetic recommendations on the level of some lipid and hemostatic parameters in offspring of parents with risk factors for coronary heart disease].
abstract: Atherosclerosis, the precursor of coronary heart disease may originate in childhood. The atherogenic potential of food is related to its cholesterol and saturated-fat content. The study population consisted of children from CHD-parents under the age 12 years with plasma total cholesterol > 170 mg/dl, LDL-Ch > 90 mg/dl and ApoB > 70 mg/dl. All the patients were advised a 6 month diet following National Program of Cholesterol Prevention recommendation. Plasma, TCh, LDL-Ch, ApoB, TG, Ch-esters saturated/unsaturated ratio and platelet factor 4 concentration decreased, LCAT activity and Ch-esters unsaturated increased during study period. We observed interesting correlation between: PF4 and ApoB, PF4 and LDL-Ch and PF4 and HDL-ECh 18:3. Our data show, that proper diet can modify risk factors of CHD in children with family history of CHD.
authors.affiliation: Zakład Biochemii Klinicznej i Diagnostyki Laboratoryjnej Pomorskiej Akademii Medycznej.
authors.forename: B
authors.initials: B
authors.lastname: Torbus-Lisiecka
authors.forename: B
authors.initials: B
authors.lastname: Szafrańska
authors.forename: T
authors.initials: T
authors.lastname: Wesołowska
authors.forename: M
authors.initials: M
authors.lastname: Jastrzebska
authors.forename: K
authors.initials: K
authors.lastname: Chełstowski
authors.forename: M
authors.initials: M
authors.lastname: Naruszewicz
mesh_terms: D001055:Apolipoproteins B / Q000097:blood; D002648:Child; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003327:Coronary Disease / Q000178:diet therapy* / Q000235:genetics* / Q000503:physiopathology; D005260:Female; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D050356:Lipid Metabolism; D008297:Male; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D001055:Apolipoproteins B; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D002784:Cholesterol
vernacular_title: Wpływ zaleceń dietetycznych na poziom niektórych parametrów lipidowych i hemostazy u potomstwa rodziców z czynnikami ryzyka choroby niedokrwiennej serca.