Pneumocystis carinii pneumonia versus wasting syndrome among AIDS cases in Puerto Rico: a survival analysis.
OBJECTIVE
To compare mortality of wasting syndrome (WS) versus Pneumocystis carinii pneumonia (PCP) in AIDS patients reported in Puerto Rico after controlling for gender, age, and CD4 levels.


METHODS
AIDS patients for which a diagnosis of WS (n = 1,180) or PCP (n = 765), who were reported to the AIDS Surveillance System of Puerto Rico between 1989 and 1992, were used to analyze the mortality risk among these diagnoses using a Cox's proportional hazard regression model.


RESULTS
Cox model showed that WS patients had a 14% to 33% reduction in mortality risk compared with PCP patients after adjusting for gender and age (95% confidence level). Mortality risks for males were 18% (95% CI: 1%, 39%) higher than females risk after adjusting for AIDS defining condition and age. It was shown that a decrease in 100 CD4 cells increased the mortality by 37% (95% CI: 16%, 62%) after adjusting for AIDS defining conditions, gender, and age.
Mayor Becerra
A M
AM
Department of Biostatistics and Epidemiology, Graduate School of Public Health, University of Puerto Rico, San Juan 00936-5067, USA.
Suárez
E
E
Morales Bedoya
A
A
D000163:Acquired Immunodeficiency Syndrome / Q000276:immunology / Q000401:mortality*; D000328:Adult; D000367:Age Factors; D000368:Aged; D018791:CD4 Lymphocyte Count; D016001:Confidence Intervals; D005260:Female; D019247:HIV Wasting Syndrome / Q000276:immunology / Q000401:mortality*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011020:Pneumonia, Pneumocystis / Q000276:immunology / Q000401:mortality*; D016016:Proportional Hazards Models; D011647:Puerto Rico / Q000453:epidemiology; D012737:Sex Factors