Study of the antiviral activity of some new classes of AS-triazine derivatives (preliminary note).
The inhibitory activity exerted by some derivatives with an asymmetrical triazine structure on the multiplication of certain viruses [parainfluenza type 1 Sendai virus, vesicular stomatitis virus, (VSV) herpes simplex type 1 virus (HSV)] was determined: the role of coupling with ribose and that of substitution by halogens on the lateral chain was pointed out.
Tomas
E
E
Stefan S. Nicolau Institute of Virology, Bucharest, Romania.
Popescu
A
A
Zuivertz
A
A
Jucu
V
V
Czabor
F
F
Cristescu
C
C
D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D002460:Cell Line; D002642:Chick Embryo; D018259:Herpesvirus 1, Human / Q000187:drug effects*; D006801:Humans; D015394:Molecular Structure; D010222:Parainfluenza Virus 1, Human / Q000187:drug effects*; D018108:Respirovirus / Q000187:drug effects*; D014227:Triazines / Q000737:chemistry / Q000494:pharmacology*; D014721:Vesicular stomatitis Indiana virus / Q000187:drug effects*
D000998:Antiviral Agents; D014227:Triazines