title: Septo-optic dysplasia associated with cerebral cortical dysplasia (cortico-septo-optic dysplasia).
abstract: It is generally accepted that there are two subsets of septo-optic dysplasia (deMorsier's syndrome), one with schizencephaly and the other without schizencephaly. A third form of the anomaly which is associated with callosal absence has also been described. Except for schizencephaly, the association of septo-optic dysplasia with another major type of disorder of neuronal migration and organization such as cortical dysplasia, has not yet been reported. We report the MR imaging examination of a 3-year-old patient with bilateral rolandic cortical dysplasia, and with apparent thinning of the optic nerves, and absent septum pellucidum (septo-optic dysplasia) as a new combination. This can be labelled as cortico-septo-optic dysplasia.
authors.affiliation: Department of Radiology, Ege University Hospital, Bornova, Izmir, Turkey.
authors.forename: R N
authors.initials: RN
authors.lastname: Sener
mesh_terms: D061085:Agenesis of Corpus Callosum; D002675:Child, Preschool; D005260:Female; D005625:Frontal Lobe / Q000002:abnormalities*; D006801:Humans; D017436:Kallmann Syndrome / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D009900:Optic Nerve / Q000002:abnormalities*; D012688:Septum Pellucidum / Q000002:abnormalities*