title: [Value of regional lymph node excision for prognosis of advanced malignant melanoma treated by perfusion of the extremity].
abstract: Staging by means of preoperative clinical screening will always stage melanoma study patients too favourably. Only a postoperative histopathological staging by means of lymphadenectomy will allow a correct stage-correlated patient prognosis. Lymphadenectomy does not prolong overall survival (95% confident intervals +/-6.6% to +/-25%) however prolongs recurrence free survival.
authors.affiliation: Klinik und Poliklinik für Chirurgie, Universität zu Köln.
authors.forename: R
authors.initials: R
authors.lastname: Huber
authors.forename: I
authors.initials: I
authors.lastname: Krüger
authors.forename: H
authors.initials: H
authors.lastname: Stützer
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage*; D017024:Chemotherapy, Adjuvant; D010478:Chemotherapy, Cancer, Regional Perfusion; D003131:Combined Modality Therapy; D005121:Extremities / Q000601:surgery*; D006801:Humans; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008545:Melanoma / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D009367:Neoplasm Staging; D011379:Prognosis; D012878:Skin Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Stellenwert der regionalen Lymphadenektomie für die Prognose des fortgeschrittenen malignen Melanoms unter Extremitätenperfusion.