title: Age and anorectal sensibility in normal women.
abstract: BACKGROUND
  Our aim was to study associations between age and anorectal sensibility in healthy women.
  
  
  METHODS
  Seventy-five women, with a mean age of 50 (range, 20-83) years, and mean parity of 2 (range, 0-4), were studied. Anal mucosa electrosensitivity (AME) was measured 1 and 2 cm from the anal verge. Rectal sensibility was also measured (minimum perceived volume (MPV), desire to defaecate (DD), and urgency (U)). Associations between anorectal sensibility and age were corrected for parity by using multiple regression analysis.
  
  
  RESULTS
  Threshold values of AME increased with age (P = 0.03) (1 cm) and P = 0.01 (2 cm)). Rectal sensibility threshold values were also positively associated with age (MPV, P = 0.003; DD, P = 0.04; and U, P = 0.06). Changes in AME were greater after menopause, whereas associations between rectal sensibility and age seemed linear.
  
  
  CONCLUSIONS
  Impairment of the anorectal sensibility appears to be part of the normal ageing process, thus increasing the risk of faecal incontinence in old women.
authors.affiliation: Dept. of Surgery L, Amtssygehuset, University Hospital of Aarhus, Denmark.
authors.forename: A M
authors.initials: AM
authors.lastname: Ryhammer
authors.forename: S
authors.initials: S
authors.lastname: Laurberg
authors.forename: K M
authors.initials: KM
authors.lastname: Bek
mesh_terms: D000375:Aging / Q000502:physiology*; D001003:Anal Canal / Q000502:physiology*; D003672:Defecation / Q000502:physiology; D004568:Electrodiagnosis; D005242:Fecal Incontinence / Q000453:epidemiology; D005260:Female; D006801:Humans; D008593:Menopause / Q000502:physiology; D008875:Middle Aged; D010298:Parity; D012007:Rectum / Q000502:physiology*; D012044:Regression Analysis; D012307:Risk Factors; D012677:Sensation / Q000502:physiology