title: Transcatheter closure of patent arterial ducts using controlled-release coils.
abstract: OBJECTIVE
  To determine the efficacy of transcatheter closure of patent arterial ducts using controlled-release coils.
  
  
  METHODS
  Transcatheter closure of patent arterial ducts was attempted in 52 patients using controlled-release coils.
  
  
  METHODS
  For the study, four tertiary paediatric cardiology units were used, two of which were in the U.K., one in Italy and one in Turkey.
  
  
  METHODS
  The 52 patients ranged in age between 3-5 months and 61 years (median 3-5 years), and weighted between 4.5 kg and 62 kg. The duct diameters were 1 mm to 6.5 mm.
  
  
  RESULTS
  In four patients the ducts were too large for safe release of the coils. In the remaining 48, one coil was inserted in 33 patients, two coils in nine, three coils in four and four coils in two patients. Immediately at the end of the procedure, the duct was completely occluded in 26/47 (55%) patients. Haemolysis occurred in one patient, in whom the coil was removed by a snare catheter and a large umbrella device was implanted with resolution of the haemolysis. Coil embolization to the pulmonary artery occurred in five (10%) patients. All were easily retrieved and replaced by larger coils. At the latest follow-up by colour Doppler echocardiography, the duct was completely occluded in 44/47 (94%) patients.
  
  
  CONCLUSIONS
  Transcatheter closure of patent arterial ducts by controlled-release coils is effective and safe. Even when more than one coil is inserted the technique is still less cumbersome and considerably cheaper than transcatheter umbrella closure.
authors.affiliation: Hacettepe University, Ankara, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Celiker
authors.forename: S A
authors.initials: SA
authors.lastname: Qureshi
authors.forename: A
authors.initials: A
authors.lastname: Bilgic
authors.forename: M
authors.initials: M
authors.lastname: Carminati
authors.forename: R
authors.initials: R
authors.lastname: Kirk
authors.forename: E
authors.initials: E
authors.lastname: Rosenthal
authors.forename: D
authors.initials: D
authors.lastname: Alehan
authors.forename: S
authors.initials: S
authors.lastname: Giusti
authors.forename: E J
authors.initials: EJ
authors.lastname: Baker
authors.forename: M
authors.initials: M
authors.lastname: Tynan
mesh_terms: D002675:Child, Preschool; D004374:Ductus Arteriosus, Patent / Q000000981:diagnostic imaging / Q000628:therapy*; D018618:Echocardiography, Doppler, Color; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011093:Polyethylene Terephthalates; D019736:Prostheses and Implants; D013193:Stainless Steel; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D011093:Polyethylene Terephthalates; D013193:Stainless Steel