Involvement of chromosomes 6 and 11 in a soft tissue chondroma.
Cytogenetic analysis of a soft tissue chondroma revealed monosomy 6 and rearrangement of chromosome 11. Previously described 12q13-q15 involvement was not found. Aberrations of chromosomes 6 and 11, however, have been reported before in this type of benign cartilaginous tumor.
Dal Cin
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P
Center for Human Genetics, University of Leuven, Belgium.
Qi
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H
Sciot
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R
Van den Berghe
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H
D000328:Adult; D002812:Chondroma / Q000235:genetics* / Q000473:pathology; D002880:Chromosomes, Human, Pair 11; D002896:Chromosomes, Human, Pair 6; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D008297:Male; D012983:Soft Tissue Neoplasms / Q000235:genetics* / Q000473:pathology