Cerebrospinal fluid viral antibodies in obsessive-compulsive disorder in an Indian population.
Immunoglobulin G viral antibodies for herpes simplex virus type 1, varicella zoster virus, cytomegalovirus, measles, and mumps were studied in 76 subjects with obsessive-compulsive disorder and compared with a control population. There was a significantly higher titer for herpes simplex virus type 1 antibodies. Sera: cerebrospinal fluid ratios were suggestive of intrathecal synthesis.
Khanna
S
S
Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.
Ravi
V
V
Shenoy
P K
PK
Chandramuki
A
A
Channabasavanna
S M
SM
D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000134:cerebrospinal fluid*; D003587:Cytomegalovirus / Q000276:immunology; D005260:Female; D018259:Herpesvirus 1, Human / Q000276:immunology; D014645:Herpesvirus 3, Human / Q000276:immunology; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid; D007194:India; D008297:Male; D008875:Middle Aged; D009109:Mumps virus / Q000276:immunology; D009771:Obsessive-Compulsive Disorder / Q000134:cerebrospinal fluid* / Q000523:psychology; D011569:Psychiatric Status Rating Scales
D000914:Antibodies, Viral; D007074:Immunoglobulin G