Vascular function in OSA.
A number of pathophysiological phenomena linked to sleep disordered breathing are likely to affect vascular function. This report briefly reviews current knowledge regarding neurogenic vascular tone and a number of circulating hormones with vascular actions in obstructive sleep apnea (OSA). New evidence suggesting a role of the vascular endothelium in the development of vascular disease in OSA is also presented.
Hedner
J
J
Department of Clinical Pharmacology, Sahlgrenska University Hospital, Göteborg, Sweden.
D000450:Aldosterone / Q000502:physiology; D000804:Angiotensin II / Q000502:physiology; D001120:Arginine / Q000502:physiology; D009320:Atrial Natriuretic Factor / Q000502:physiology; D004727:Endothelium / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000150:complications; D012891:Sleep Apnea Syndromes / Q000150:complications*; D012913:Snoring / Q000150:complications; D013564:Sympathetic Nervous System / Q000502:physiology
D000804:Angiotensin II; D000450:Aldosterone; D009320:Atrial Natriuretic Factor; D001120:Arginine