Defining the skeletal elements.
A recent study of mice carrying different combinations of mutations in the genes for two bone morphogenetic factors (BMPs), BMP5 and GDF5, indicates that BMPs have specific and synergistic functions in the regulation of skeleton development.
Vortkamp
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Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.
D000818:Animals; D001846:Bone Development; D019485:Bone Morphogenetic Proteins / Q000235:genetics / Q000502:physiology*; D001842:Bone and Bones / Q000002:abnormalities; D006133:Growth Substances / Q000502:physiology*; D006801:Humans; D051379:Mice; D008817:Mice, Mutant Strains; D009024:Morphogenesis; D015398:Signal Transduction
D019485:Bone Morphogenetic Proteins; D006133:Growth Substances