title: Enlargement glycogen store in rat liver and muscle by fructose-diet intake and exercise training.
abstract: This study investigated the effect of long-term intake of a fructose diet and exercise training on glycogen content in liver and skeletal muscle in female rats. Thirty-six rats (8 wk old) were divided into two dietary groups and were fed with a control (chow) diet or fructose diet (containing 20%) fructose) for 12 wk. During this period, one-half of the rats in each dietary group were trained by using a motor-driven treadmill (running speed of 25 m/min and duration of 90 min/day, 5 days/wk). The liver glycogen was increased by intake of a fructose diet and exercise training, and the content was in the following order: control-diet and sedentary rats < fructose-diet and sedentary rats < or = control-diet and trained rats < fructose-diet and trained rats in the ratio of 1:3.4:3.6:5.0. The glycogen content in gastrocnemius muscle showed the same trend as that in liver; the ratio was 1:1.3:1.3:1.6. These results indicate that both long-term intake of the fructose diet and exercise training synergistically increased glycogen in both tissues.
authors.affiliation: Department of Bioscience, Nagoya Institute of Technology, Gokiso, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Murakami
authors.forename: Y
authors.initials: Y
authors.lastname: Shimomura
authors.forename: N
authors.initials: N
authors.lastname: Fujitsuka
authors.forename: M
authors.initials: M
authors.lastname: Sokabe
authors.forename: K
authors.initials: K
authors.lastname: Okamura
authors.forename: S
authors.initials: S
authors.lastname: Sakamoto
mesh_terms: D000818:Animals; D004435:Eating / Q000502:physiology*; D005260:Female; D005632:Fructose / Q000494:pharmacology*; D006003:Glycogen / Q000378:metabolism*; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D009132:Muscles / Q000187:drug effects / Q000378:metabolism*; D010805:Physical Conditioning, Animal / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D005632:Fructose; D006003:Glycogen