The ATP-regulated K+ channel in mitochondria: five years after its discovery.
Mitochondria contain a potassium specific channel (mitoKATP channel) sensitive to ATP and antidiabetic sulfonylureas. The mitochondrial KATP channel plays an important role in the mitochondrial volume control and in regulation of the components of protonmotive force. This minireview describes the properties and current hypotheses concerning the function of mitoKATP channel.
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M. Nencki Institute of Experimental Biology, Warsaw, Poland.
D018528:ATP-Binding Cassette Transporters; D000818:Animals; D054086:KATP Channels; D008928:Mitochondria / Q000378:metabolism*; D015221:Potassium Channels / Q000378:metabolism*; D024661:Potassium Channels, Inwardly Rectifying
D018528:ATP-Binding Cassette Transporters; D054086:KATP Channels; D015221:Potassium Channels; D024661:Potassium Channels, Inwardly Rectifying; C092520:uK-ATP-1 potassium channel