title: [Effect of post-trauma endotoxemia on production of IL-1 beta in burn patients].
abstract: Thermal injury-associated endotoxemia affects the in vitro induction of interleukin-1 beta (IL-1 beta) synthesis by inflammatory stimuli. Pathophysiological effects related to the interaction between bacterial endotoxins and human monocytes/marcrophages are complex and may have significant impact on defense response of burn host. Therapeutic approaches in critically ill burn patients should be considered in the context of the overall biological activity of endogenous mediators of immune and inflammatory reactions involved.
authors.affiliation: Laboratorium Wirusologii, Instytutu Immunologii i Terapii Doświadczalnej PAN im. L. Hirszfelda we Wrocławiu.
authors.forename: M
authors.initials: M
authors.lastname: Cembrzyńska-Nowak
mesh_terms: D002056:Burns / Q000150:complications*; D016022:Case-Control Studies; D002478:Cells, Cultured; D019446:Endotoxemia / Q000209:etiology* / Q000276:immunology / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000276:immunology; D007375:Interleukin-1 / Q000096:biosynthesis* / Q000276:immunology; D008264:Macrophages / Q000378:metabolism; D009000:Monocytes / Q000378:metabolism
chemical_list: D007375:Interleukin-1
vernacular_title: Wpływ pourazowej endotoksemii na producke IL-1 beta u chorych poparzonych.