Drug nephrotoxicity: an overview.
Drug-induced nephrotoxicity is common in clinical practice and should be sought out by clinicians seeking to understand the causes of renal disease and renal syndromes in particular patients. Insights into the pathophysiology of drug-induced disorders should provide clues to disease mechanisms which ultimately might lead to better treatments and more rational prevention of all renal diseases.
Bennett
W M
WM
Division of Nephrology, Hypertension, and Clinical Pharmacology, Oregon Health Sciences University, Portland 97201, USA.
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000175:diagnosis; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use; D016572:Cyclosporine / Q000009:adverse effects* / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D007668:Kidney / Q000187:drug effects* / Q000473:pathology; D007676:Kidney Failure, Chronic / Q000139:chemically induced / Q000175:diagnosis
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D007166:Immunosuppressive Agents; D016572:Cyclosporine