title: Management of the thyroid gland with laryngectomy for cT3 glottic carcinomas.
abstract: Is routine hemithyroidectomy justified in laryngectomy for laryngeal carcinoma? Hemithyroidectomy with laryngectomy causes hypothyroidism in up to 25% of patients, and if combined with radiotherapy, in up to 70%. In this review of 102 total laryngectomies with routine hemithyroidectomy for cT3 glottic carcinoma, laryngeal carcinoma involved the thyroid gland in two. Both had subglottic tumour extension. The tumour approached within 3 mm of the thyroid capsule in seven. It is proposed that thyroidectomy should be performed only in selected laryngeal carcinomas. Intraoperative assessment of the thyroid gland should determine the need for thyroidectomy in glottic and transglottic carcinomas. Carcinoma invasion of the thyroid gland should be confirmed by frozen section before proceeding to thyroidectomy. In the absence of thyroid gland involvement, both thyroid lobes may be preserved. Total thyroidectomy should be performed if the thyroid gland has been invaded. Total thyroidectomy should be routinely performed with subglottic carcinomas.
authors.affiliation: Department of Otolaryngology, Groote Schuur Hospital, Cape Town, South Africa.
authors.forename: J J
authors.initials: JJ
authors.lastname: Fagan
authors.forename: P V
authors.initials: PV
authors.lastname: Kaye
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005260:Female; D005931:Glottis / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007037:Hypothyroidism / Q000209:etiology; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D009361:Neoplasm Invasiveness; D011183:Postoperative Complications; D012189:Retrospective Studies; D013961:Thyroid Gland / Q000473:pathology / Q000601:surgery* / Q000648:ultrastructure