Evidence of peripheral hearing asymmetry in humans: clinical implications.
Auditory system hemispheric asymmetry in language processing is well-established, and there are many indications of lateralization as of the peripheral auditory system i.e., as of the cochlea. The left ear is more susceptible to noise damage; tinnitus is more predominant there, while spontaneous otoacoustic emissions (SOAEs) are more often found in the right ear. The present study addressed the following two questions: Does this right-ear SOAE prevalence exist as early as preterm birth? Is there any functional asymmetry in the medial olivo-cochlear (MOC) efferent system, known to modulate outer hair cell contractions? The study involved 483 preterm neonates (gestional age: 24-37 weeks) and 70 right-handed adults (age: 18-31 years). In each ear, SOAEs and evoked otoacoustic emissions (EOAEs) were recorded and analysed, and, for the adults, functional MOC system assessment was made. Results showed SOAEs and EOAE amplitude to be right-predominant and in adults a right MOC functional predominance. These results indicate peripheral auditory system lateralisation, and an early origin thereof. The MOC system being thought to play a protective role, its physiological lateralisation may be relevant to the left prevalence of tinnitus and of auditory fatigue.
Khalfa
S
S
Department of Otolaryngology, Perception and Auditory Mechanisms, CNRS UPRESA 5020, Lyon, France.
Morlet
T
T
Micheyl
C
C
Morgon
A
A
Collet
L
L
D000161:Acoustic Stimulation; D000293:Adolescent; D000328:Adult; D000375:Aging / Q000502:physiology; D001306:Auditory Pathways / Q000502:physiology; D003051:Cochlea / Q000502:physiology; D005260:Female; D007839:Functional Laterality; D006309:Hearing / Q000502:physiology*; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000502:physiology; D008297:Male; D009847:Olivary Nucleus / Q000502:physiology; D017084:Otoacoustic Emissions, Spontaneous