title: Structure of HBP, a multifunctional protein with a serine proteinase fold.
abstract: The structure of human heparin binding protein reveals that the serine proteinase fold has been used as a scaffold for a multifunctional protein with antibacterial activity, monocyte and t-cell activating properties and endotoxin and heparin binding capacity.
authors.forename: L F
authors.initials: LF
authors.lastname: Iversen
authors.forename: J S
authors.initials: JS
authors.lastname: Kastrup
authors.forename: S E
authors.initials: SE
authors.lastname: Bjørn
authors.forename: P B
authors.initials: PB
authors.lastname: Rasmussen
authors.forename: F C
authors.initials: FC
authors.lastname: Wiberg
authors.forename: H J
authors.initials: HJ
authors.lastname: Flodgaard
authors.forename: I K
authors.initials: IK
authors.lastname: Larsen
mesh_terms: D023181:Antimicrobial Cationic Peptides; D001665:Binding Sites; D001798:Blood Proteins / Q000737:chemistry* / Q000378:metabolism; D002352:Carrier Proteins; D003198:Computer Simulation; D004731:Endotoxins / Q000378:metabolism; D006493:Heparin / Q000378:metabolism; D006801:Humans; D019272:Leukocyte Elastase / Q000737:chemistry; D008050:Lipid A / Q000378:metabolism; D008958:Models, Molecular; D017434:Protein Structure, Tertiary; D012697:Serine Endopeptidases / Q000737:chemistry* / Q000378:metabolism
chemical_list: C062991:AZU1 protein, human; D023181:Antimicrobial Cationic Peptides; D001798:Blood Proteins; D002352:Carrier Proteins; D004731:Endotoxins; D008050:Lipid A; D006493:Heparin; D012697:Serine Endopeptidases; D019272:Leukocyte Elastase