[Pharmacological specificities and modalities of prescriptions for corticoids for asthmatic adults].
The efficacy of corticosteroids in asthma has been recognized over 40 years ago. Since that time, the advent of inhaled forms has further improved the therapeutic of these drugs which are now recognized as the fundamental treatment for asthma, and described in detail by national and international consensus. Based on a large body of literature, it can now be recommended to prescribe inhaled corticosteroids for symptomatic asthma patients. Long-term treatment is required and dosage not exceeding 1000 micrograms/d (beclometasone dipropionate equivalent) in adults are safe. Differences in the pharmacological characteristics of the various systematic and inhaled corticosteroids can be used to adapt treatment and administration route to each patient and achieve good patient compliance with optimal therapeutic efficacy.
Demoly
P
P
Maladies respiratoires-INSERM U454, Hôpital Arnaud de Villeneuve, Montpellier.
Jaffuel
D
D
Chung
K F
KF
Bousquet
J
J
Michel
F B
FB
Godard
P
P
D000280:Administration, Inhalation; D000284:Administration, Oral; D000328:Adult; D001249:Asthma / Q000188:drug therapy* / Q000378:metabolism; D005938:Glucocorticoids / Q000008:administration & dosage* / Q000493:pharmacokinetics; D006801:Humans
D005938:Glucocorticoids
Spécificités pharmacologiques et modalités de prescription des corticoïdes dans l'asthme de l'adulte.