title: Arterial changes after thrombolysis and percutaneous transluminal angioplasty in vertebrobasilar thrombosis.
abstract: We present clinicopathologic findings in a patient treated with intraarterial thrombolysis and angioplasty for vertebrobasilar thrombosis. Autopsy revealed a marked inflammatory infiltrate within the vertebral artery at the site of catheter manipulation. This finding may have important implications for the use of interventional angiography in cerebrovascular disease.
authors.affiliation: Department of Neurology, Johns Hopkins Hospital, Baltimore, Md., USA.
authors.forename: K J
authors.initials: KJ
authors.lastname: Becker
authors.forename: B J
authors.initials: BJ
authors.lastname: Crain
authors.forename: L H
authors.initials: LH
authors.lastname: Monsein
authors.forename: P A
authors.initials: PA
authors.lastname: Pappalardo
authors.forename: D F
authors.initials: DF
authors.lastname: Hanley
mesh_terms: D000800:Angioplasty, Balloon / Q000295:instrumentation*; D003131:Combined Modality Therapy; D004730:Endothelium, Vascular / Q000187:drug effects / Q000293:injuries / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000473:pathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D015912:Thrombolytic Therapy / Q000295:instrumentation*; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage* / Q000009:adverse effects; D014711:Vertebral Artery / Q000187:drug effects / Q000293:injuries / Q000473:pathology*; D014715:Vertebrobasilar Insufficiency / Q000473:pathology / Q000628:therapy*
chemical_list: D014568:Urokinase-Type Plasminogen Activator