Apoptosis of germinal centers in postnatal development of rabbit tonsil.
The purpose of this study was to clarify the relationship between the morphological maturation of the germinal center of newborn rabbit tonsil and the appearance of apoptosis in it. Germinal centers were observed using immunostaining. Apoptosis is shown to be scarce in immature type of germinal center, but abundant in mature type. The findings suggest apoptosis to have an important function in the germinal center of the tonsil.
Kawabata
I
I
ENT Department, Saitama Medical Center, Saitama Medical School, Japan.
Homma
T
T
Tabe
H
H
Koba
R
R
D000818:Animals; D000831:Animals, Newborn; D017209:Apoptosis; D004848:Epithelium / Q000648:ultrastructure; D018858:Germinal Center / Q000502:physiology* / Q000648:ultrastructure*; D008214:Lymphocytes / Q000502:physiology / Q000648:ultrastructure; D014066:Palatine Tonsil / Q000502:physiology* / Q000648:ultrastructure*; D011817:Rabbits