title: [Chronic granulomatous chorioretinitis in tuberculosis].
abstract: BACKGROUND
  Though the incidence of tuberculosis decreased substantially during the second half of the century, a steady increase of new cases has been observed within the last decade. Among other reasons, the growing number of immunodeficient patients (e.g. HIV, therapy with immunosuppressive agents) and migration from underdeveloped to industrial countries contribute to this finding.
  
  
  METHODS
  A 57-year-old male patient presented with a history of chronic bilateral chorioretinitis of unknown origin. During the last months a marked decrease in visual acuity of the left eye was noted. Prior diagnostic attempts had not led to a specific diagnosis. Notable was the history of long-term systemic corticosteroid therapy for chronic obstructive lung disease. Funduscopy of the right eye revealed a choroidal granuloma with adjacent serous retinal detachment. Both eyes showed multiple dot-like lesions in the retinal pigment epithelium of the posterior pole. Finally the diagnosis could be made by isolating Mycobacterium tuberculosis from sputum samples and gastric aspirate. Within a few weeks after starting tuberculostatic therapy the ocular symptoms regressed and the visual acuity improved significantly.
  
  
  CONCLUSIONS
  Securing the diagnosis of tuberculous uveitis is often difficult. The differential diagnosis includes other granulomatous ocular inflammations. The detection of Mycobacterium tuberculosis and the clinical course make the diagnosis most likely.
  
  
  CONCLUSIONS
  Tuberculosis should always be included in the differential diagnosis as a possible etiology for uveitis, particularly in those cases taking a chronic course. Despite the recent emergence of drug-resistant strains in most cases tuberculosis is a well curable disease.
authors.affiliation: Klinik für Ophthalmologie, Christian-Albrechts-Universität zu Kiel.
authors.forename: G
authors.initials: G
authors.lastname: Häring
authors.forename: B
authors.initials: B
authors.lastname: Nölle
authors.forename: K
authors.initials: K
authors.lastname: Kiehne
authors.forename: B
authors.initials: B
authors.lastname: Wiechens
mesh_terms: D002825:Chorioretinitis / Q000175:diagnosis*; D002908:Chronic Disease; D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000175:diagnosis; D014392:Tuberculosis, Ocular / Q000175:diagnosis*; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis
vernacular_title: Chronische granulomatöse Chorioretinitis bei Tuberkulose.