Strategies to reduce the need for peri-operative blood transfusion.
Therapeutic regimens involving the transfusion of blood components are a matter of debate, not only with regard to patients' safety, but also with regard to cost-effectiveness. The following different measures to reduce the use of blood components and their efficacy are discussed: autologous transfusion, including predonation, isovolaemic haemodilution and peri-operative retransfusion; toleration of a lower haematocrit; and measures to reduce blood loss. In particular, a combination of these methods may be most effective at reducing transfusion needs.
Mertes
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N
Klinik und Poliklinik für Anästhesiologie, Westfälischen Wilhelms-Universität Münster, Germany.
Booke
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M
Van Aken
H
H
D016063:Blood Loss, Surgical / Q000517:prevention & control*; D001803:Blood Transfusion / Q000191:economics; D001804:Blood Transfusion, Autologous / Q000009:adverse effects / Q000191:economics; D006801:Humans; D065227:Transfusion Reaction