Paranoid psychosis due to flecainide toxicity in malignant neuropathic pain.
Flecainide was used to treat malignant neuropathic pain but despite using therapeutic doses, toxicity occurred resulting in paranoid psychosis. Monitoring of flecainide levels in vulnerable populations is suggested to guide prescribing.
Bennett
M I
MI
St. James's University Hospital, Leeds, UK.
D000889:Anti-Arrhythmia Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001917:Brachial Plexus; D005424:Flecainide / Q000506:poisoning* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy*; D010166:Palliative Care; D010259:Paranoid Disorders / Q000139:chemically induced*; D010523:Peripheral Nervous System Diseases / Q000209:etiology / Q000503:physiopathology; D012509:Sarcoma / Q000150:complications; D012782:Shoulder; D012983:Soft Tissue Neoplasms / Q000150:complications*
D000889:Anti-Arrhythmia Agents; D005424:Flecainide