Mechanistic investigation of the reduction in antimicrobial activity of ciprofloxacin by metal cations.
Ma
H H
HH
Department of Pharmacy, Faculty of Medicine, Chinese University of Hong Kong, Shatin, Hong Kong.
Chiu
F C
FC
Li
R C
RC
D000535:Aluminum / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D002412:Cations / Q000494:pharmacology; D002614:Chelating Agents / Q000737:chemistry / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D002939:Ciprofloxacin / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects / Q000378:metabolism; D007700:Kinetics; D008274:Magnesium / Q000494:pharmacology; D008345:Manganese / Q000494:pharmacology; D008670:Metals / Q000494:pharmacology*; D013997:Time Factors
D000890:Anti-Infective Agents; D002412:Cations; D002614:Chelating Agents; D008670:Metals; D008345:Manganese; D002939:Ciprofloxacin; D000535:Aluminum; D008274:Magnesium