title: Analysis of the affinity of each haptoglobin polymer for hemoglobin by two-dimensional affinity electrophoresis.
abstract: Using polyacrylamide gel electrophoresis we have often encountered a decrease in the high molecular weight polymers of haptoglobin 2-1 in the serum of patients after transfusion and with hemolytic diseases. Using two-dimensional affinity electrophoresis we have attributed this phenomenon to the high affinity of high molecular weight polymers of the haptoglobin 2-1 for hemoglobin.
authors.affiliation: Department of Forensic Science, School of Allied Health Science, Kitasato University, Sagamihara City, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Okazaki
authors.forename: Y
authors.initials: Y
authors.lastname: Yanagisawa
authors.forename: T
authors.initials: T
authors.lastname: Nagai
mesh_terms: D001704:Biopolymers / Q000378:metabolism*; D015180:Electrophoresis, Gel, Two-Dimensional; D006242:Haptoglobins / Q000378:metabolism*; D006454:Hemoglobins / Q000378:metabolism*; D006801:Humans; D011485:Protein Binding
chemical_list: D001704:Biopolymers; D006242:Haptoglobins; D006454:Hemoglobins