[Determination of cardiac troponin I on Stratus analyzer: prospective evaluation in unstable angina].
Cardiac troponin I (troponin lc) has been measured on the Dade Stratus analyzer. Cardiac specificity has been studied in patients presenting a rhabdomyolysis syndrome. The obtained results clearly demonstrated that this parameter may be used as a specific marker of myocardial injury, in contrast to total creatine kinase- or mass CK-MB measurements. In unstable angina, two groups of patients may be defined: one group with elevated troponin lc (> 0.60 microgram/L; 31 patients, group I), one other with normal troponin lc (< 0.35 microgram/L; 49 patients; group II). Quantitative angiographic analysis was performed on 50 patients including 18 patients from group I. Group I showed a more severe culprit lesion than group II. All the results suggested that troponin Ic might be an indicator of severity in unstable angina.
Quillard
M
M
Laboratoire de biochimie, hôpital Charles-Nicolle, Rouen France.
Koning
R
R
Andres
H
H
Cauliez
B
B
Hue
G
G
Letac
B
B
Matray
F
F
Lavoinne
A
A
D000328:Adult; D000789:Angina, Unstable / Q000097:blood* / Q000150:complications; D003402:Creatine Kinase / Q000032:analysis / Q000097:blood; D005260:Female; D015200:Fluoroimmunoassay; D006801:Humans; D007527:Isoenzymes; D008297:Male; D011446:Prospective Studies; D012206:Rhabdomyolysis / Q000150:complications; D019210:Troponin I / Q000097:blood*
D007527:Isoenzymes; D019210:Troponin I; D003402:Creatine Kinase
Dosage de la troponine I cardiaque sur l'automate Stratus: évaluation prospective dans I'angor instable.