title: [Wilson's disease].
abstract: Wilson's disease is a rare inherited metabolic disorder usually characterized by liver and/or neurological degeneration. Unlike most genetically transmitted diseases, it rapidly responds to pharmacological treatment in case of early diagnosis and treatment. Often, however, as this disease presents with aspecific symptoms, patients are wrongly diagnosed as psychiatric cases or as having generic chronic liver disease and the true cause of symptoms is only discovered at a much later stage. The authors give a detailed review of the literature with the aim of presenting the most recent research on the main aspects of this disease and offering a practical and simple approach to early diagnosis.
authors.affiliation: Cattedra di Medicina Interna, Università, Palermo.
authors.forename: G
authors.initials: G
authors.lastname: Bonfissuto
authors.forename: C
authors.initials: C
authors.lastname: Magliarisi
authors.forename: M
authors.initials: M
authors.lastname: Soresi
authors.forename: F
authors.initials: F
authors.lastname: Bascone
authors.forename: G
authors.initials: G
authors.lastname: Costanza
authors.forename: A
authors.initials: A
authors.lastname: Carroccio
authors.forename: G
authors.initials: G
authors.lastname: Montalto
mesh_terms: D000293:Adolescent; D000328:Adult; D002614:Chelating Agents / Q000627:therapeutic use; D003937:Diagnosis, Differential; D006527:Hepatolenticular Degeneration / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D010396:Penicillamine / Q000627:therapeutic use; D014266:Trientine / Q000627:therapeutic use; D015032:Zinc / Q000627:therapeutic use
chemical_list: D002614:Chelating Agents; D010396:Penicillamine; D015032:Zinc; D014266:Trientine
vernacular_title: Morbo di Wilson.