The influence of Pseudomonas aeruginosa on liposomes.
The interaction of liposomes loaded with Ponceau red (used as a marker) with Pseudomonas aeruginosa cells was observed and it resulted in marker leakage. The marker leakage from liposomes was low in physiological fluids. The interaction was independent of secreted phospholipase C level and the serotype of the tested strain. Six of 37 examined isolates did not cause any release of the marker from the liposomes. Marker release of over 50% of total encapsulated material was observed only for ten of the strains tested.
Antos
M
M
Department of Microbiology, Military Institute of Hygiene and Epidemiology, Warszawa, Poland.
Trafny
E A
EA
Grzybowski
J
J
D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D015169:Colony Count, Microbial; D004396:Coloring Agents / Q000008:administration & dosage*; D004337:Drug Carriers; D008081:Liposomes; D009994:Osmolar Concentration; D010740:Phospholipases / Q000378:metabolism; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000201:enzymology* / Q000276:immunology; D013696:Temperature; D010738:Type C Phospholipases / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D004396:Coloring Agents; D004337:Drug Carriers; D008081:Liposomes; D010740:Phospholipases; D010738:Type C Phospholipases