title: [Pathogenetic validation of optimal antioxidant therapy in suppurative inflammatory otic diseases in children].
abstract: The knowledge of cell-molecular characteristics of middle ear inflammation in children allowed the authors to suggest a beneficial effect of antioxidants in this disease. The trial of ascorbic acid, retinol and alpha-tocopherol as components of combined treatment has confirmed this hypophysis in view of high response achieved in children with middle ear purulent inflammation.
authors.affiliation: Department of Otorhinolaryngology, University of People's Friendship, Russia.
authors.forename: K E
authors.initials: KE
authors.lastname: Karabaev
authors.forename: V F
authors.initials: VF
authors.lastname: Antoniv
authors.forename: R U
authors.initials: RU
authors.lastname: Bekmuradov
mesh_terms: D000293:Adolescent; D000975:Antioxidants / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001205:Ascorbic Acid / Q000493:pharmacokinetics / Q000627:therapeutic use*; D002462:Cell Membrane / Q000187:drug effects / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D006801:Humans; D007223:Infant; D015227:Lipid Peroxidation / Q000502:physiology; D010032:Otitis Externa / Q000188:drug therapy / Q000378:metabolism; D010035:Otitis Media, Suppurative / Q000188:drug therapy* / Q000378:metabolism; D013053:Spectrophotometry; D016896:Treatment Outcome; D014801:Vitamin A / Q000493:pharmacokinetics / Q000627:therapeutic use*; D014810:Vitamin E / Q000493:pharmacokinetics / Q000627:therapeutic use*
chemical_list: D000975:Antioxidants; D004338:Drug Combinations; D014801:Vitamin A; D014810:Vitamin E; C048974:vitamin A, vitamin E drug combination; D001205:Ascorbic Acid
vernacular_title: Patogeneticheskoe obosnovanie ratsional'noi antioksidantnoi terapii pri gnoino-vospalitel'nykh zablevaniiakh ukha u detei.