title: Two new isomers of domoic acid from a red alga, Chondria armata.
abstract: Isodomoic acids G and H, two new isomers of the neurotoxin domoic acid, along with isodomoic acids A, B, E and F, were isolated from a red alga, Chondria armata, collected at the southern tip of Kyushu Island. The structures of two of these were deduced to be (E, E) and (Z, E) isomers of 2-carboxy-4-(5-carboxy-l-methyl-2-hexenylidene)-3-pyrro- lidineacetic acid, based on electrospray ionization mass and [1H]nuclear magnetic resonance spectral analyses including [1H-1H]correlation spectroscopy and nuclear Overhauser effect correlation spectroscopy.
authors.affiliation: Laboratory of Marine Botany and Environmental Science, Faculty of Fisheries, Kagoshima University, Japan.
authors.forename: L
authors.initials: L
authors.lastname: Zaman
authors.forename: O
authors.initials: O
authors.lastname: Arakawa
authors.forename: A
authors.initials: A
authors.lastname: Shimosu
authors.forename: Y
authors.initials: Y
authors.lastname: Onoue
authors.forename: S
authors.initials: S
authors.lastname: Nishio
authors.forename: Y
authors.initials: Y
authors.lastname: Shida
authors.forename: T
authors.initials: T
authors.lastname: Noguchi
mesh_terms: D002851:Chromatography, High Pressure Liquid; D007536:Isomerism; D007608:Kainic Acid / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D009467:Neuromuscular Depolarizing Agents / Q000032:analysis / Q000737:chemistry / Q000302:isolation & purification*; D000461:Rhodophyta
chemical_list: D009467:Neuromuscular Depolarizing Agents; C012301:domoic acid; D007608:Kainic Acid