title: Rapid spongiform degeneration of the cerebrum and cerebellum in Creutzfeldt-Jakob encephalitis: serial MR findings.
abstract: We report the cerebral MR imaging findings in a patient with pathologically proved Creutzfeldt-Jakob disease in whom predominant gray and white matter degeneration was seen within 1 year of symptom onset. The initial MR signal abnormalities in the basal ganglia were subtle. A follow-up MR examination revealed diffuse cerebral and cerebellar atrophy and demyelination.
authors.affiliation: Department of Diagnostic Radiology, Tri-Service General Hospital, National Defensive Medical Center, Taipei, Taiwan, Republic of China.
authors.forename: B C
authors.initials: BC
authors.lastname: Tzeng
authors.forename: C Y
authors.initials: CY
authors.lastname: Chen
authors.forename: C C
authors.initials: CC
authors.lastname: Lee
authors.forename: F H
authors.initials: FH
authors.lastname: Chen
authors.forename: T Y
authors.initials: TY
authors.lastname: Chou
authors.forename: R A
authors.initials: RA
authors.lastname: Zimmerman
mesh_terms: D001284:Atrophy; D001479:Basal Ganglia / Q000473:pathology; D001706:Biopsy; D002531:Cerebellum / Q000473:pathology*; D002540:Cerebral Cortex / Q000473:pathology*; D007562:Creutzfeldt-Jakob Syndrome / Q000175:diagnosis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009410:Nerve Degeneration / Q000502:physiology; D009413:Nerve Fibers, Myelinated / Q000473:pathology