title: Mixed connective tissue disease associated with acute polyradiculoneuropathy.
abstract: A rare case of mixed connective tissue disease (MCTD) with acute polyradiculoneuropathy is reported. A 23-year-old woman presented with high body temperature, arthralgia and a headache, and developed gait disturbance two weeks later. She had many clinical features common to patients with MCTD. Her neurological manifestations were diagnosed as acute polyradiculoneuropathy based on the clinical picture, combined with supportive ancillary data, including cerebrospinal fluid (CSF) analysis, electrophysiological evaluation, sural nerve biopsy, peroneus brevis muscle biopsy, and magnetic resonance imaging (MRI). Her neurologic deficits, as well as associated laboratory findings, were improved by corticosteroid therapy.
authors.affiliation: Second Department of Internal Medicine, Nagoya City University Medical School.
authors.forename: E
authors.initials: E
authors.lastname: Katada
authors.forename: K
authors.initials: K
authors.lastname: Ojika
authors.forename: M
authors.initials: M
authors.lastname: Uemura
authors.forename: K
authors.initials: K
authors.lastname: Maeno
authors.forename: S
authors.initials: S
authors.lastname: Mitake
authors.forename: Y
authors.initials: Y
authors.lastname: Tsugu
authors.forename: Y
authors.initials: Y
authors.lastname: Otsuka
authors.forename: T
authors.initials: T
authors.lastname: Iwase
mesh_terms: D000208:Acute Disease; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008947:Mixed Connective Tissue Disease / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D011128:Polyradiculopathy / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D011239:Prednisolone