Supplementation with lutein (4 months) and alpha-tocopherol (2 months), in separate or combined oral doses, in control men.
As part of a European project to test if 'the consumption of diets rich in carotenoids reduces oxidative damage to human tissue components', 15 mg/day lutein and 100 mg/day alpha-tocopherol were supplied to ten volunteers. alpha-Tocopherol (alone and combined) provoked an increase in alpha-tocopherol and a decrease in gamma-tocopherol serum levels. Lutein levels increased during the first month (given alone) in all controls but they behaved very differently during the following 3 months. Ketocarotenoids (not supplied) increased whereas anhydroluteins (not supplied) did not change, suggesting that they are formed in vivo.
Olmedilla
B
B
Servicio de Nutriciòn, Clinica Puerta de Hierro, Madrid, Spain.
Granado
F
F
Gil-Martinez
E
E
Blanco
I
I
D000328:Adult; D004032:Diet; D006801:Humans; D014975:Lutein / Q000008:administration & dosage* / Q000097:blood / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D013030:Spain; D013997:Time Factors; D014810:Vitamin E / Q000008:administration & dosage* / Q000097:blood
D014810:Vitamin E; D014975:Lutein