title: Stevens-Johnson syndrome associated with methazolamide treatment reported in two Japanese-American women.
abstract: BACKGROUND
  Systemic acetazolamide treatment has been reported in association with Stevens-Johnson syndrome (SJS). This is the first report of this syndrome associated with methazolamide treatment. The association is reported in two Japanese-American women.
  
  
  RESULTS
  Two patients with SJS, which developed during treatment with methazolamide, are described. Other potential associations are discussed.
  
  
  CONCLUSIONS
  Systemically administered carbonic anhydrase inhibitors, including both acetazolamide and methazolamide can be associated with SJS.
authors.affiliation: University of California, San Francisco Medical Center, Department of Ophthalmology, Corte Madera 94976, USA.
authors.forename: A J
authors.initials: AJ
authors.lastname: Flach
authors.forename: R E
authors.initials: RE
authors.lastname: Smith
authors.forename: F T
authors.initials: FT
authors.lastname: Fraunfelder
mesh_terms: D000328:Adult; D000368:Aged; D002257:Carbonic Anhydrase Inhibitors / Q000009:adverse effects*; D005128:Eye Diseases / Q000139:chemically induced* / Q000208:ethnology / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007564:Japan / Q000208:ethnology; D008704:Methazolamide / Q000009:adverse effects*; D013262:Stevens-Johnson Syndrome / Q000139:chemically induced* / Q000208:ethnology / Q000473:pathology; D014481:United States / Q000453:epidemiology
chemical_list: D002257:Carbonic Anhydrase Inhibitors; D008704:Methazolamide