Renal K+ channels: structure and function.
The activity of potassium (K+) channels is intimately linked to several important transport functions in renal tubules. We review recent progress concerning the properties, site along the nephron, and physiological regulation of native K+ channels, and compare their characteristics with those of recently cloned K+ channels. We do not fully cover work on K+ channels in amphibian tubules, cell cultures, and single tubule cells and do not review K+ channels in mesangial cells.
Wang
W
W
Department of Pharmacology, New York Medical College, Valhalla 10595, USA.
Hebert
S C
SC
Giebisch
G
G
D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D007668:Kidney / Q000378:metabolism*; D007685:Kidney Tubules, Collecting / Q000166:cytology / Q000378:metabolism; D007687:Kidney Tubules, Proximal / Q000378:metabolism; D008138:Loop of Henle / Q000378:metabolism; D008968:Molecular Conformation; D015221:Potassium Channels / Q000737:chemistry* / Q000378:metabolism / Q000502:physiology*; D013329:Structure-Activity Relationship
D015221:Potassium Channels