title: The surgical team as a source of postoperative wound infections caused by Streptococcus pyogenes.
abstract: Postoperative wound infection, caused by Streptococcus pyogenes transmitted during the operation from members of the surgical team, is a rare but serious complication of surgery. This study describes three cases, which could be traced to an orthopaedic surgeon, who carried the epidemic strain in this throat. Epidemiological characteristics of 14 other outbreaks, published in the English-language literature, are summarized. In total, these 15 outbreaks involved 136 patients. The overall case fatality rate was 12%. Anaesthesiologists and other assisting staff members were involved more often than surgeons and obstetricians. In outbreaks where an attack rate could be calculated, it was at least 7%. T-28 was the most commonly involved T-type, accounting for seven outbreaks. The anus and vagina were the most common carrier sites in staff members. A combination of penicillin and oral vancomycin seemed to be the most efficient treatment for anal and vaginal carriage. Relapse of carriage could occur several months after apparent eradication, and was often associated with a carrier in the family household.
authors.affiliation: Department of Clinical Microbiology, Hvidovre Hospital, University of Copenhagen, Denmark.
authors.forename: H J
authors.initials: HJ
authors.lastname: Kolmos
authors.forename: R N
authors.initials: RN
authors.lastname: Svendsen
authors.forename: S V
authors.initials: SV
authors.lastname: Nielsen
mesh_terms: D000368:Aged; D002353:Carrier State; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D017053:Infection Control; D017757:Infectious Disease Transmission, Professional-to-Patient; D008297:Male; D008505:Medical Staff, Hospital; D009985:Orthopedics; D010348:Patient Care Team; D013290:Streptococcal Infections / Q000635:transmission*; D013297:Streptococcus pyogenes; D013530:Surgical Wound Infection / Q000635:transmission*