Radiation dose from a phosphorous-32 impregnated wire mesh vascular stent.
The near field dose distribution of a realistic vascular stent impregnated with radioactive 32P is calculated employing the dose-point-kernel (DPK) method in a homogeneous and uniform medium. The cylindrical wire mesh geometry for the Palmaz-Schatz [Palmaz-Schatz is a tradename of Cordis (a Johnson & Johnson company)] stent is incorporated in the model calculation, and the dose distribution generated by the beta particles emitted from the decayed radioactive 32P is computed at distances ranging from 0.1 to 2 mm exterior to the stent surface. Dose measurements were obtained using radiochromic film dosimetry media on an actual Palmaz-Schatz half-stent impregnated with 32P using ion implantation, and compared to the DPK model predictions. The close agreement between the model calculation and the film dosimetry data confirms the validity of the model which can be adapted to a variety of different stent designs.
Janicki
C
C
Centre hospitalier, Université de Montréal, Québec, Canada.
Duggan
D M
DM
Coffey
C W
CW
Fischell
D R
DR
Fischell
T A
TA
D015906:Angioplasty, Balloon, Coronary; D055592:Biophysical Phenomena; D001703:Biophysics; D001918:Brachytherapy / Q000379:methods* / Q000706:statistics & numerical data; D003327:Coronary Disease / Q000532:radiotherapy* / Q000601:surgery*; D005373:Film Dosimetry; D006801:Humans; D008962:Models, Theoretical; D010761:Phosphorus Radioisotopes / Q000627:therapeutic use*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D012008:Recurrence; D015607:Stents; D013679:Technology, Radiologic
D010761:Phosphorus Radioisotopes