title: Lung surfactant: a personal perspective.
abstract: This perspective tells the story of the discovery, characterization, and understanding of the surfactant system of the lung; of how investigators from many disciplines studied the system, stimulated by the demonstration of surfactant deficiency in respiratory distress syndrome of the newborn; and of how the resulting knowledge formed a basis for highly successful surfactant substitution treatment for this syndrome. The chapter includes personal reminiscences and reflections of the author and ends with a few thoughts about the present status and future prospects of this field of research.
authors.affiliation: Cardiovascular Research Institute, University of California, San Francisco 94143-0130, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Clements
mesh_terms: D049673:History, 20th Century; D006801:Humans; D010827:Physiology / Q000266:history*; D011663:Pulmonary Surfactants / Q000266:history*; D012106:Research / Q000266:history; D014481:United States
chemical_list: D011663:Pulmonary Surfactants