Cyclopia: craniofacial appearance on MR and three-dimensional CT.
In a case of alobar holoprosencephaly, a neonate who died several minutes after birth was found to have multiple facial and intracranial malformations, including cyclopia. Postmortem MR and CT findings included a single midline orbit, with two globes that contained separate lenses supplied by a single optic nerve. There were two separate superior orbital fissures and two separate lateral rectus muscles.
Liu
D P
DP
Department of Radiology, beth Israel Medical Center, New York, NY 10003, USA.
Burrowes
D M
DM
Qureshi
M N
MN
D000015:Abnormalities, Multiple / Q000175:diagnosis*; D001921:Brain / Q000002:abnormalities / Q000473:pathology; D019465:Craniofacial Abnormalities / Q000175:diagnosis*; D005123:Eye / Q000473:pathology; D005124:Eye Abnormalities / Q000175:diagnosis*; D005260:Female; D006679:HIV Seropositivity / Q000175:diagnosis; D016142:Holoprosencephaly / Q000175:diagnosis*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D009900:Optic Nerve / Q000002:abnormalities / Q000473:pathology; D009915:Orbit / Q000002:abnormalities / Q000473:pathology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis; D014057:Tomography, X-Ray Computed