90K (Mac-2 BP) in human milk.
Human 90K, also known as Mac-2 binding protein (Mac-2 BP), is a secreted glycoprotein which is widely expressed, binds to the human macrophage-associated lectin Mac-2, and may have a role in host defence. We have measured the concentrations of 90K in human breast milk from eight healthy mothers delivering mature healthy infants after full-term pregnancy using a specific immunoenzymatic assay. Maximal 90K concentrations were observed on days 2-3 post-partum, and ranged from 13.4 to 79.2 microg/ml. The concentrations of 90K in the milk had no correlation with those in the maternal blood.
D'Ostilio
N
N
Cattedra di Oncologia Medica, Università G. D' Annunzio, Chieti, Italy.
Sabatino
G
G
Natoli
C
C
Ullrich
A
A
Iacobelli
S
S
D000328:Adult; D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D015153:Blotting, Western; D002352:Carrier Proteins / Q000032:analysis* / Q000097:blood / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006023:Glycoproteins / Q000032:analysis* / Q000097:blood / Q000276:immunology; D006801:Humans; D007231:Infant, Newborn; D008895:Milk, Human / Q000276:immunology*; D016326:Extracellular Matrix Proteins
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D002352:Carrier Proteins; D006023:Glycoproteins; C081856:LGALS3BP protein, human; D016326:Extracellular Matrix Proteins