[The results of kidney transplantation].
The mortality associated with renal transplantation is 4% at the first year essentially because of infection. Transplant losses are 5 to 10%, essentially due to rejection. The graft loss rate is approximately 5% per year over the following years. The half-life of cadaver kidneys is 8 years, depending on HLA compatibilities, the level of acute tubular necrosis, and the donor's age. Seronegative patients who receive a kidney from a seropositive donor have a higher risk of CMV infection. The origin of the initial nephrological disease affects graft survival, particularly in the case of segmental and focal hyaline disease. The half-life of semi-identical donor grafts is 15 years and 25 years for an identical living donor. The results obtained by transplantations performed from unrelated living donors are better than those obtained from cadaver kidneys.
D000367:Age Factors; D001424:Bacterial Infections / Q000401:mortality; D002102:Cadaver; D003586:Cytomegalovirus Infections / Q000453:epidemiology / Q000635:transmission; D005602:France / Q000453:epidemiology; D005923:Glomerulosclerosis, Focal Segmental / Q000453:epidemiology; D006084:Graft Rejection / Q000453:epidemiology; D006085:Graft Survival; D006680:HLA Antigens / Q000032:analysis; D006648:Histocompatibility; D006801:Humans; D007674:Kidney Diseases / Q000453:epidemiology; D016030:Kidney Transplantation / Q000009:adverse effects / Q000401:mortality; D007683:Kidney Tubular Necrosis, Acute / Q000453:epidemiology; D019520:Living Donors / Q000706:statistics & numerical data; D012307:Risk Factors; D014019:Tissue Donors / Q000706:statistics & numerical data; D016896:Treatment Outcome
D006680:HLA Antigens
Résultats de la transplantation rénale.