Sodium amobarbital memory tests: what do they predict?
Severe transient postoperative memory deficits among epilepsy patients with resection from one temporal lobe may be indicative of increased risk for amnesia had more extensive removal of mesial structures occurred. Immediate postoperative testing may provide some validation for risk of amnesia as predicted by the intracarotid sodium amobarbital memory test (IAP-M). Thirty patients (24 not considered at risk for amnesia and 5 who failed the IAP-M) were tested on the first, second, and third days following resection from the right or left temporal lobe. Results suggest that the IAP-M paradigm used does not necessarily predict postoperative memory performance.
Dade
L A
LA
Montreal Neurological Institute and Hospital, McGill University, Canada.
Jones-Gotman
M
M
D000647:Amnesia / Q000175:diagnosis* / Q000209:etiology*; D000654:Amobarbital; D000704:Analysis of Variance; D002541:Cerebral Decortication / Q000009:adverse effects*; D003147:Communication Disorders / Q000209:etiology; D004292:Dominance, Cerebral / Q000502:physiology; D004833:Epilepsy, Temporal Lobe / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006993:Hypnotics and Sedatives; D008137:Longitudinal Studies; D008297:Male; D008568:Memory / Q000502:physiology; D009483:Neuropsychological Tests / Q000592:standards; D010364:Pattern Recognition, Visual / Q000502:physiology; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D013997:Time Factors; D014706:Verbal Learning / Q000502:physiology
D006993:Hypnotics and Sedatives; D000654:Amobarbital