Fiber-optic laser-Doppler anemometer microscope applied to the cerebral microcirculation in rats.
We have applied our developed fiber-optic laser-Doppler anemometer microscope (FLDAM) for the study of the cerebral microcirculation in the rat. The red cell velocity in single pial microvessels was successfully measured through a closed cranial window for the vessel diameter range from 7.8 to 230 microns. The temporal resolution of the FLDAM was sufficiently high to detect the pulsation in the arterioles. Arterio-venous distributions of the temporal mean red cell velocity and wall shear rate are also described.
Seki
J
J
Department of Biomedical Engineering, National Cardiovascular Center Research Institute, Osaka, Japan.
Sasaki
Y
Y
Oyama
T
T
Yamamoto
J
J
D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D002560:Cerebrovascular Circulation / Q000502:physiology*; D003201:Computers; D004912:Erythrocytes / Q000502:physiology; D005336:Fiber Optic Technology; D017078:Laser-Doppler Flowmetry; D008297:Male; D008833:Microcirculation; D008856:Microscopy, Fluorescence; D055100:Optical Fibers; D051381:Rats; D017208:Rats, Wistar; D013314:Stress, Mechanical