Advances in the treatment of Paget's bone disease.
Remission is now possible for many patients. The underlying aggressiveness of osteoclast-mediated bone resorption can be inhibited- and often abrogated-with the new aminobisphosphonates. Long-term complications of Paget's disease may thus be substantially reduced in frequency and severity.
Weinstein
R S
RS
Bone Histomorphometry Laboratory, McCleilen Veterans Affairs Medical Center, Little Rock, USA.
D000368:Aged; D004164:Diphosphonates / Q000494:pharmacology / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D010001:Osteitis Deformans / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D012008:Recurrence; D012074:Remission Induction; D013997:Time Factors
D004164:Diphosphonates