title: The effects of IFN-gamma activated mouse peritoneal and alveolar macrophages on Cryptosporidium parvum development.
abstract: Mouse peritoneal and alveolar macrophages were interacted in vitro with C. parvum oocysts and cultured in normal medium and in medium with IFN-gamma. The results showed that in vitro activation of macrophages by IFN-gamma limits C. parvum development although the inhibitory effect is not as potent as in other intracellular parasitic protozoa.
authors.affiliation: Institute of Biotechnology, School of Science, University of Granada, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Martinez
authors.forename: M J
authors.initials: MJ
authors.lastname: Rosales
authors.forename: J
authors.initials: J
authors.lastname: Diaz
authors.forename: C
authors.initials: C
authors.lastname: Mascaro
mesh_terms: D000818:Animals; D002478:Cells, Cultured; D016785:Cryptosporidium parvum / Q000254:growth & development*; D007371:Interferon-gamma / Q000494:pharmacology*; D008262:Macrophage Activation; D016676:Macrophages, Alveolar / Q000187:drug effects / Q000276:immunology* / Q000469:parasitology*; D017737:Macrophages, Peritoneal / Q000187:drug effects / Q000276:immunology* / Q000469:parasitology*; D051379:Mice; D013997:Time Factors
chemical_list: D007371:Interferon-gamma