title: Thyroid disease in the west of Ireland: an atypical incidence of neoplasia.
abstract: This study was established to review the spectrum of thyroid disease presenting to a regional centre in the West of Ireland. Over a ten year period 414 thyroidectomies were performed. The most common histological diagnosis was nodular goitre (238 patients). There were 134 thyroid neoplasms; 87 (65%) adenomas, 40 (30%) carcinomas and 7 (5%) lymphomas. A breakdown of the cancers revealed 17 (36%) papillary and 14 (30%) follicular carcinomas with 7 (15%) lymphomas. Six (13%) patients presented with anaplastic tumors. Solitary nodules had a high cancer risk (25%) in comparison with multinodular or diffuse goitres (5%). Thyroiditis accounted for 38 cases while only 10 thyroidectomies were performed for Graves' disease.
authors.affiliation: Department of Surgery (and Histopathology), University College Hospital, Galway.
authors.forename: D M
authors.initials: DM
authors.lastname: O'Hanlon
authors.forename: M P
authors.initials: MP
authors.lastname: Little
authors.forename: H F
authors.initials: HF
authors.lastname: Given
authors.forename: D S
authors.initials: DS
authors.lastname: Quill
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000453:epidemiology; D002291:Carcinoma, Papillary / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007494:Ireland / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D013959:Thyroid Diseases / Q000453:epidemiology*; D013964:Thyroid Neoplasms / Q000453:epidemiology*