Histamine up-regulates the generation of nitric oxide, and nitric oxide down-regulates the release of histamine in cardiovascular preparations.
Mannaioni
P F
PF
Department of Preclinical and Clinical Pharmacology, University of Florence, Italy.
Bello
M G
MG
Di Bello
M G
MG
Schunack
W
W
Masini
E
E
D000818:Animals; D002320:Cardiovascular Physiological Phenomena; D002319:Cardiovascular System / Q000187:drug effects*; D002417:Cattle; D002478:Cells, Cultured; D003326:Coronary Circulation / Q000187:drug effects; D017259:Dimaprit / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006168:Guinea Pigs; D006632:Histamine / Q000494:pharmacology*; D017442:Histamine Agonists / Q000494:pharmacology; D006636:Histamine Release / Q000187:drug effects*; D008297:Male; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology; D009569:Nitric Oxide / Q000378:metabolism* / Q000494:pharmacology*; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors; D019323:omega-N-Methylarginine / Q000494:pharmacology
D004791:Enzyme Inhibitors; D017442:Histamine Agonists; D019323:omega-N-Methylarginine; D009569:Nitric Oxide; D006632:Histamine; D019001:Nitric Oxide Synthase; D017259:Dimaprit