Indocyanine green angiography of acute multifocal posterior placoid pigment epitheliopathy.
OBJECTIVE
To understand the pathophysiology of acute multifocal posterior placoid pigment epitheliopathy (AMPPPE).


METHODS
Indocyanine green (ICG) angiography was used for three patients, four eyes with acute AMPPPE and four eyes with healed AMPPPE.


RESULTS
The angiographic photographs demonstrated widespread choroidal hypofluorescence of the active and healed lesions.


CONCLUSIONS
Although the pathogenesis and histopathology of AMPPPE are unknown, the literature suggests that AMPPPE may represent an inflammatory reaction, possibly a delayed-type hypersensitivity reaction. The ICG choroidal hypofluorescence in AMPPPE is probably due to partial choroidal vascular occlusion secondary to occlusive vasculitis.
Park
D
D
Schatz
H
H
McDonald
H R
HR
Johnson
R N
RN
D000208:Acute Disease; D000328:Adult; D002829:Choroid / Q000098:blood supply / Q000473:pathology; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology* / Q000503:physiopathology; D012164:Retinal Diseases / Q000473:pathology* / Q000503:physiopathology; D014657:Vasculitis / Q000473:pathology; D014792:Visual Acuity
D004396:Coloring Agents; D007208:Indocyanine Green