title: The impact of hydrosalpinx on successful pregnancy in tubal factor infertility treated by in vitro fertilization.
abstract: OBJECTIVE
  To determine the impact of hydrosalpinx on pregnancy rates in patients undergoing IVF for infertility caused by tubal disease.
  
  
  METHODS
  Review of the records of all patients who had undergone IVF for tubal factor infertility at our institution between May 1988 and October 1994.
  
  
  METHODS
  A university-sponsored, hospital-based IVF facility.
  
  
  METHODS
  Two hundred fifty patients were identified with infertility due to tubal disease; 67 of these had at least one documented hydrosalpinx whereas the remaining 183 did not.
  
  
  METHODS
  Numbers of oocytes retrieved and fertilized, the number of embryos transferred and implanting, and resulting pregnancy rates.
  
  
  RESULTS
  The groups were similar in age and cycle cancellation rates. The patients with hydrosalpinx had greater numbers of oocytes retrieved per cycle (15.0 versus 11.6) and embryos transferred per cycle then those without hydrosalpinges (4.21 versus 3.98). The hydrosalpinx group also undertook more cycles per patient (2.31 versus 1.96). Fertilization rates between the two groups were similar, but implantation rates were decreased in those with hydrosalpinx (8.5% versus 11.2%).
  
  
  CONCLUSIONS
  Hydrosalpinx did not result in impaired ovarian stimulation or decreased oocyte fertilization. It did, however, interfere with implantation and reduce to some degree the success of IVF in achieving an ongoing pregnancy. The validity of routine salpingectomy for hydrosalpinx is debatable, but its use in selected individuals may well be appropriate.
authors.affiliation: Department of Obstetrics and Gynecology, Women and Infants Hospital, Brown University School of Medicine, Providence, Rhode Island.
authors.forename: A S
authors.initials: AS
authors.lastname: Blazar
authors.forename: J W
authors.initials: JW
authors.lastname: Hogan
authors.forename: D B
authors.initials: DB
authors.lastname: Seifer
authors.forename: G N
authors.initials: GN
authors.lastname: Frishman
authors.forename: C A
authors.initials: CA
authors.lastname: Wheeler
authors.forename: R V
authors.initials: RV
authors.lastname: Haning
mesh_terms: D000022:Abortion, Spontaneous / Q000453:epidemiology; D010064:Embryo Implantation; D004624:Embryo Transfer; D005184:Fallopian Tube Diseases / Q000150:complications*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000209:etiology*; D008297:Male; D009865:Oocytes; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D013081:Sperm Motility