[Retrospective estimation of the frequency of heterozygous beta-thalassemia in the Crimean Tatar population. Estimation of gene frequency in the ancestral population based on mixed population data with a known admixture rate].
Results of the maximum-likelihood estimation of heterozygous beta-thalassemia frequency in the Crimean Tartar ancestral population obtained by evaluating the gametic contribution of Uzbeks to the Crimean Tartar ethnic group are presented. The computing algorithm is given, and reliability of the obtained results is discussed.
Asanov
A Iu
AIu
Sergeev
A S
AS
D000465:Algorithms; D005006:Ethnicity / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D006579:Heterozygote; D006801:Humans; D008297:Male; D010063:Ovum; D015203:Reproducibility of Results; D012189:Retrospective Studies; D013094:Spermatozoa; D014610:Uzbekistan; D017086:beta-Thalassemia / Q000235:genetics*
Retrospektivnaia otsenka chastoty geterozigotnoĭ beta-talassemii v populiatsii krymskikh tatar. Otsenka chastoty gena v predkovoĭ populiatsii po dannym smeshannoĭ populiatsii pri izvestnoĭ dole smesheniia.