T cell receptor delta locus polymorphism in rheumatoid arthritis.
In order to identify new susceptibility markers for Rheumatoid Arthritis (RA), we analysed the dinucleotide repeat polymorphism at the T cell receptor delta locus (TCRD) in 65 RA patients and 99 healthy Belgian controls. A significant under-representation of the A4-A5 TCRD genotype was observed in the RA population.
Vandevyver
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Dr L. Willems-Instituut, Department of Immunology/Biotechnology, Diepenbeek, Belgium.
Geusens
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Cassiman
J J
JJ
Raus
J
J
D000483:Alleles; D001172:Arthritis, Rheumatoid / Q000453:epidemiology / Q000235:genetics* / Q000276:immunology*; D001483:Base Sequence; D001530:Belgium / Q000453:epidemiology; D016022:Case-Control Studies; D017931:DNA Primers / Q000235:genetics; D018900:Dinucleotide Repeats; D005787:Gene Frequency; D005838:Genotype; D015804:HLA-DR4 Antigen / Q000235:genetics; D006801:Humans; D011110:Polymorphism, Genetic; D016692:Receptors, Antigen, T-Cell, gamma-delta / Q000235:genetics*
D017931:DNA Primers; D015804:HLA-DR4 Antigen; D016692:Receptors, Antigen, T-Cell, gamma-delta