title: [Hyperthyroidism in TSH-producing hypophyseal adenoma].
abstract: METHODS
  For 5 years a 59-year-old man had been treated with thyrostatic drugs for hyperthyroidism of unknown aetiology. As he had been losing weight, computed tomography had been performed in the search for a malignancy. It revealed a hypophyseal space-occupying lesion.
  
  
  METHODS
  Peripheral thyroid hormone activities were raised, while thyroid-stimulating hormone (TSH) was also raised to 12.4 mU/l and there was evidence of partial hypophyseal insufficiency. Octreotide scintigraphy demonstrated increased activity in the area of the hypophysis.
  
  
  METHODS
  The transsphenoidal surgery and immunohistochemical tests confirmed the diagnosis of TSH-producing hypophyseal adenoma. The patient became euthyroid after the operation.
  
  
  CONCLUSIONS
  TSH-producing hypophyseal adenoma should be considered as a rare cause of hyperthyroidism when it is combined with non-suppressed TSH.
authors.affiliation: Klinik für Endokrinologie und Stoffwechselkrankheiten, Otto-von-Guericke-Universität Magdeburg.
authors.forename: K
authors.initials: K
authors.lastname: Reschke
authors.forename: T
authors.initials: T
authors.lastname: Rohrer
authors.forename: D
authors.initials: D
authors.lastname: Kopf
authors.forename: S
authors.initials: S
authors.lastname: Klose
authors.forename: O
authors.initials: O
authors.lastname: Hey
authors.forename: A
authors.initials: A
authors.lastname: Perneczky
authors.forename: H
authors.initials: H
authors.lastname: Lehnert
mesh_terms: D000236:Adenoma / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery; D001971:Bromocriptine; D005500:Follow-Up Studies; D006801:Humans; D006980:Hyperthyroidism / Q000209:etiology*; D007016:Hypophysectomy; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015282:Octreotide; D010911:Pituitary Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000601:surgery; D011877:Radionuclide Imaging; D013972:Thyrotropin / Q000378:metabolism*; D013997:Time Factors
chemical_list: D001971:Bromocriptine; D013972:Thyrotropin; D015282:Octreotide
vernacular_title: Hyperthyreose bei TSH-produzierendem Hypophysenadenom.