title: Abscess formation around a hydroxyapatite-coated implant placed into the extraction socket with autogenous bone graft. A histological study using light microscopy, image processing, and confocal laser scanning microscopy.
abstract: The purpose of this study was to evaluate the radiologic, histologic, and histometric findings for a retrieved hydroxyapatite (HA)-coated implant which had been placed into a fresh extraction socket with autogenous bone graft 3 months previously. A periapical radiography disclosed a vertical bone loss around the implant cervix. Examination of histologic section disclosed that granulation tissue including bone chips around the cervix, and newly-formed bone tissue around the grafted bone tissue on the HA coated surface. In the confocal laser scanning microscopic findings toluidine blue-negative bone tissue showed autofluorescence. Histometric analysis indicated that the average percent bone contact was 29.2% (ranged 26.4% to 34.1%). Suspected reasons for failure were an early exposure of the barrier membrane, its early removal, the implant placement into an infected site, inadequate antibiotic premedication, and/or poor control of infections around teeth prior to implant surgery and around implants before and after placement of barrier membrane.
authors.affiliation: Faculty of Dentistry, Kyushu University, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Takeshita
authors.forename: S
authors.initials: S
authors.lastname: Iyama
authors.forename: Y
authors.initials: Y
authors.lastname: Ayukawa
authors.forename: T
authors.initials: T
authors.lastname: Suetsugu
authors.forename: M
authors.initials: M
authors.lastname: Oishi
mesh_terms: D000038:Abscess / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D000368:Aged; D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D000539:Alveolar Process / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000473:pathology; D019072:Antibiotic Prophylaxis; D016025:Bone Transplantation / Q000009:adverse effects; D003758:Dental Implantation, Endosseous / Q000009:adverse effects; D015921:Dental Implants / Q000009:adverse effects; D017886:Durapatite; D005453:Fluorescence; D006097:Granulation Tissue / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D016557:Guided Tissue Regeneration, Periodontal / Q000009:adverse effects; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007576:Jaw, Edentulous, Partially / Q000601:surgery; D008297:Male; D008336:Mandibular Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000382:microbiology / Q000473:pathology; D008567:Membranes, Artificial; D018613:Microscopy, Confocal; D016348:Osseointegration; D011138:Polytetrafluoroethylene; D011859:Radiography
chemical_list: D015921:Dental Implants; D008567:Membranes, Artificial; D011138:Polytetrafluoroethylene; D017886:Durapatite