Reactivity of anti-glycophorin monoclonal antibodies (Mabs) in tests with red cells of non-human primates.
Seventy Mabs against human glycophorins (GP) and band 3 were tested with red blood cells (RBCs) of various non-human primates, from anthropoid apes to monkeys. Differences among Mabs reactivity in tests with non-human primate RBCs reflect the complexity of the immune reactions to human GPs and provide insights into aspects of evolution and a tool to epitope map.
Blancher
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A
Laboratoire d'Immunogénétique moléculaire, Université Paul Sabatier, Hôpital Purpan, Toulouse, France.
Socha
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Reid
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ME
D000818:Animals; D000911:Antibodies, Monoclonal; D000937:Antigen-Antibody Reactions / Q000276:immunology*; D002520:Cercopithecidae; D018604:Epitope Mapping; D004912:Erythrocytes / Q000276:immunology*; D006021:Glycophorins / Q000276:immunology*; D006071:Gorilla gorilla; D006922:Hylobates; D002679:Pan troglodytes; D011148:Pongo pygmaeus; D011323:Primates / Q000276:immunology*
D000911:Antibodies, Monoclonal; D006021:Glycophorins