title: Myasthenia gravis and the Miller-Fisher variant of Guillain-Barré syndrome.
abstract: This review primarily concerns two issues. First, in myasthenia gravis, what mechanisms are likely to underlie the low threshold for extraocular muscle involvement in this disease? Second, what is the likely importance of anti-GQ1b ganglioside antibodies in the diagnosis and causation of Miller-Fisher syndrome?
authors.affiliation: Neurosciences Group, University of Oxford, John Radcliffe Hospital, UK.
authors.forename: J
authors.initials: J
authors.lastname: Newsom-Davis
mesh_terms: D001323:Autoantibodies / Q000097:blood; D003937:Diagnosis, Differential; D005732:Gangliosides / Q000276:immunology; D006801:Humans; D009157:Myasthenia Gravis / Q000175:diagnosis* / Q000276:immunology; D009801:Oculomotor Muscles / Q000276:immunology; D009886:Ophthalmoplegia / Q000175:diagnosis* / Q000276:immunology; D011129:Polyradiculoneuropathy / Q000175:diagnosis* / Q000276:immunology; D011950:Receptors, Cholinergic / Q000276:immunology; D012021:Reflex, Abnormal / Q000502:physiology
chemical_list: D001323:Autoantibodies; D005732:Gangliosides; D011950:Receptors, Cholinergic; C039129:GQ1b ganglioside