title: Varying clinical course of large placental chorioangiomas. Report of 3 cases.
abstract: Three cases of placental chorioangiomas, from 6.5 to 10 cm in diameter, were diagnosed prenatally by ultrasound and color Doppler imaging at 21-34 weeks of gestation. In 1 case, due to fetal hydrops and maternal 'mirror syndrome', immediate delivery of a neonate, who was severely anemic, thrombocytopenic and had consumption coagulopathy, was required. In the other 2 pregnancies, conservative management was possible, once fetal cardiac failure and anemia were ruled out by the combination of fetal blood sampling and serial echographic and Doppler investigations.
authors.affiliation: 1st Department of Obstetrics and Gynecology, University of Milan, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Zoppini
authors.forename: B
authors.initials: B
authors.lastname: Acaia
authors.forename: G
authors.initials: G
authors.lastname: Lucci
authors.forename: L
authors.initials: L
authors.lastname: Pugni
authors.forename: B
authors.initials: B
authors.lastname: Tassis
authors.forename: U
authors.initials: U
authors.lastname: Nicolini
mesh_terms: D000328:Adult; D000740:Anemia / Q000209:etiology; D002585:Cesarean Section; D004211:Disseminated Intravascular Coagulation / Q000209:etiology; D005260:Female; D005315:Fetal Diseases / Q000209:etiology; D005865:Gestational Age; D006391:Hemangioma / Q000000981:diagnostic imaging*; D006801:Humans; D010922:Placenta Diseases / Q000000981:diagnostic imaging*; D011247:Pregnancy; D011256:Pregnancy Outcome; D013921:Thrombocytopenia / Q000209:etiology; D018615:Ultrasonography, Doppler, Color