A new tool in white blood cell reduction for packed red cells: 5 log depletion.
The recent development of new filters used for leucocyte reduction aims at restricting the number of leucocytes to a threshold where their undesirable effects can be minimized or excluded. In this paper we describe the performance of a new filter named BIO R01 MAX and claimed by the manufacturer to perform 5 Log10 depletion. The results show that the efficiency of the filter reached 5 Log10 depletion and the absolute number of white blood cells in the post-filtration units is always less than 2 x 10(4) with considerable safety in the prevention of transfusion reactions.
Bontadini
A
A
Servizio di Immunoematologia e Transfusionale, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Fruet
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F
Conte
R
R
D017707:Erythrocyte Transfusion; D005374:Filtration / Q000295:instrumentation; D006801:Humans; D007937:Leukapheresis / Q000295:instrumentation*