title: Fiber-optic laser-Doppler anemometer microscope applied to the cerebral microcirculation in rats.
abstract: We have applied our developed fiber-optic laser-Doppler anemometer microscope (FLDAM) for the study of the cerebral microcirculation in the rat. The red cell velocity in single pial microvessels was successfully measured through a closed cranial window for the vessel diameter range from 7.8 to 230 microns. The temporal resolution of the FLDAM was sufficiently high to detect the pulsation in the arterioles. Arterio-venous distributions of the temporal mean red cell velocity and wall shear rate are also described.
authors.affiliation: Department of Biomedical Engineering, National Cardiovascular Center Research Institute, Osaka, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Seki
authors.forename: Y
authors.initials: Y
authors.lastname: Sasaki
authors.forename: T
authors.initials: T
authors.lastname: Oyama
authors.forename: J
authors.initials: J
authors.lastname: Yamamoto
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D002560:Cerebrovascular Circulation / Q000502:physiology*; D003201:Computers; D004912:Erythrocytes / Q000502:physiology; D005336:Fiber Optic Technology; D017078:Laser-Doppler Flowmetry; D008297:Male; D008833:Microcirculation; D008856:Microscopy, Fluorescence; D055100:Optical Fibers; D051381:Rats; D017208:Rats, Wistar; D013314:Stress, Mechanical