Avoiding fluoroquinolone resistance. Strategies for primary care practice.
The therapeutic usefulness of fluroquinolones for serious and difficult-to-treat infections is well documented. However, with increasing reports of organisms becoming resistant to the agents (most often the pseudomonads, staphylococci, and streptococci), the usefulness of this class of antibiotics is being threatened. Appropriate and judicious prescribing of this class of antimicrobials can greatly aid in preserving the therapeutic value of fluoroquinolones for the treatment of infections in the future.
Stratton
C W
CW
Vanderbilt University School of Medicine, Nashville, Department of Pathology, Vanderbilt University School of Medicine, TN 37232-2561, USA. charles.stratton@mcmail.vanderbilt.edu
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy*; D004352:Drug Resistance, Microbial / Q000502:physiology; D004359:Drug Therapy, Combination; D024841:Fluoroquinolones; D006801:Humans; D016106:Methicillin Resistance; D011550:Pseudomonas aeruginosa / Q000187:drug effects; D013211:Staphylococcus aureus / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D024841:Fluoroquinolones