Diffusion imaging with a multi-echo MISSTEC sequence.
An imaging method is presented to measure the water-diffusion coefficient. The sequence (MISSTEC) uses the simultaneous acquisition of a spin echo and several stimulated echoes with the same intensity except for diffusion weighting. The optimal number of stimulated echoes was calculated to minimize the diffusion coefficient error (D). D values obtained in vitro and in vivo were in good agreement with those from the spin-echo sequence (IntraVoxel Incoherent Motion [IVIM] method). The total acquisition time is half that of the classic IVIM method.
Franconi
F
F
Unité INSERM U316, Faculté de Médecine, Tours, France.
Lethimonnier
F
F
Sonier
C B
CB
Pourcelot
L
L
Akoka
S
S
D001921:Brain / Q000033:anatomy & histology*; D004058:Diffusion; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D008959:Models, Neurological; D019047:Phantoms, Imaging; D012016:Reference Values; D012680:Sensitivity and Specificity