Adhesion of insect cells expressing the feline herpesvirus type 1 hemagglutinin (gD) to feline cell lines.
Feline herpesvirus type 1 (FHV-1) gD-expressing Sf9 cells adhered to two feline cell lines, but not to the porcine, bovine, or canine cell lines tested. In addition, this adhesion activity was inhibited by a monoclonal antibody against FHV-1 gD. These results showed that the FHV-1 gD might bind to a specific-molecule(s) on the surface of feline cell lines. We discussed a possible importance of the FHV-1 gD in host cell restriction to FHV-1 infection.
Maeda
K
K
Department of Veterinary Microbiology, Faculty of Agriculture, University of Tokyo, Japan.
Ono
M
M
Kawaguchi
Y
Y
Okazaki
K
K
Yokoyama
N
N
Tohya
Y
Y
Mikami
T
T
D018138:Alphaherpesvirinae / Q000276:immunology*; D000818:Animals; D000911:Antibodies, Monoclonal / Q000032:analysis / Q000276:immunology / Q000494:pharmacology; D000956:Antigens, Viral / Q000032:analysis / Q000276:immunology; D002371:Cat Diseases / Q000276:immunology / Q000473:pathology; D002415:Cats / Q000196:embryology / Q000276:immunology*; D002417:Cattle; D002448:Cell Adhesion / Q000187:drug effects / Q000502:physiology; D002460:Cell Line; D004285:Dogs; D005333:Fetus / Q000166:cytology*; D006389:Hemagglutinins, Viral / Q000032:analysis / Q000378:metabolism*; D006566:Herpesviridae Infections / Q000276:immunology / Q000473:pathology / Q000662:veterinary; D007313:Insecta / Q000166:cytology* / Q000276:immunology; D007668:Kidney / Q000166:cytology* / Q000196:embryology; D009036:Moths / Q000166:cytology* / Q000276:immunology; D013552:Swine
D000911:Antibodies, Monoclonal; D000956:Antigens, Viral; D006389:Hemagglutinins, Viral