title: An unusual manifestation of bleeding diathesis in a patient with osteogenesis imperfecta.
abstract: We present the anaesthetic and surgical management, and post-operative course of a patient with osteogenesis imperfecta which exemplifies the problems associated with this condition. The observed petechial haemorrhagic rash is not characteristic of the bleeding tendency in osteogenesis imperfecta nor characteristic of acute disseminated intravascular coagulation. Despite potential life-threatening complications the patient made a good recovery and was discharged 3 weeks after surgery.
authors.affiliation: Department of Anaesthetics, Royal National Orthopaedic Hospital Trust, Stanmore, Middlesex, UK.
authors.forename: G
authors.initials: G
authors.lastname: Edge
authors.forename: B
authors.initials: B
authors.lastname: Okafor
authors.forename: M E
authors.initials: ME
authors.lastname: Fennelly
authors.forename: A O
authors.initials: AO
authors.lastname: Ransford
mesh_terms: D000328:Adult; D000771:Anesthesia, Intravenous; D005260:Female; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D010013:Osteogenesis Imperfecta / Q000150:complications* / Q000473:pathology / Q000601:surgery; D011183:Postoperative Complications / Q000473:pathology*; D012128:Respiratory Distress Syndrome / Q000503:physiopathology; D014139:Tracheostomy