Cytotoxic triterpenes from Cleome africana.
Eighteen dammarane-type triterpenes were obtained from the whole plant of Cleome africana by means of cytotoxic bioassay-directed fractionation. Twelve of them were novel compounds whose structures were elucidated by various spectroscopic methods.
Nagaya
H
H
Katakura Industry Co., Ltd., Sayama, Japan.
Tobita
Y
Y
Nagae
T
T
Itokawa
H
H
Takeya
K
K
Halim
A F
AF
Abdel-Halim
O B
OB
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D017691:Caribbean Region; D002470:Cell Survival / Q000187:drug effects*; D007941:Leukemia P388; D008519:Medicine, Traditional; D051379:Mice; D015394:Molecular Structure; D010946:Plants, Medicinal; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D014315:Triterpenes