title: Effect of chronic trypanosomiasis on the bioavailability of alpha-difluoromethylornithine (DFMO) after oral administration: pharmacokinetics study on DFMO plasma levels in infected and noninfected mice using a high-performance liquid chromatography assay.
authors.affiliation: Biologie et Contrôle des Organismes Parasites, Faculté de Pharmacie, Université de Paris XI, France.
authors.forename: P M
authors.initials: PM
authors.lastname: Loiseau
authors.forename: O
authors.initials: O
authors.lastname: Chauffert
authors.forename: M
authors.initials: M
authors.lastname: Czok
mesh_terms: D000818:Animals; D001682:Biological Availability; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D000518:Eflornithine / Q000097:blood / Q000493:pharmacokinetics*; D005260:Female; D051379:Mice; D014344:Trypanocidal Agents / Q000097:blood / Q000493:pharmacokinetics*; D014346:Trypanosoma brucei brucei; D014353:Trypanosomiasis, African / Q000378:metabolism*
chemical_list: D014344:Trypanocidal Agents; D000518:Eflornithine