Models of thin filament assembly in cardiac and skeletal muscle.
The assembly and functional characteristics of many contractile proteins are different in skeletal and cardiac muscle. Two models for thin filament assembly are consistent with observations from recent studies focused on determining the functional significance of actin filament capping in primary cultures of embryonic chick myogenic cells and cardiac myocytes. Future experiments will test the validity of the proposed models for in vivo embryonic development.
Gregorio
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Department of Cell Biology and Anatomy, University of Arizona, Tucson 85724, USA.
D008841:Actin Cytoskeleton / Q000737:chemistry / Q000648:ultrastructure*; D000818:Animals; D002352:Carrier Proteins / Q000737:chemistry / Q000648:ultrastructure; D003285:Contractile Proteins / Q000737:chemistry / Q000648:ultrastructure; D006801:Humans; D008840:Microfilament Proteins / Q000737:chemistry / Q000648:ultrastructure; D018482:Muscle, Skeletal / Q000737:chemistry / Q000648:ultrastructure*; D009206:Myocardium / Q000737:chemistry / Q000648:ultrastructure*; D051348:Tropomodulin
D002352:Carrier Proteins; D003285:Contractile Proteins; D008840:Microfilament Proteins; D051348:Tropomodulin