Drug-induced antisynthetase syndrome.
We present a case of antisynthetase syndrome whose predominant feature was fibrosing alveolitis and which may have been drug-induced. This responded well to steroids and cyclophosphamide.
Thickett
D R
DR
Royal United Hospital, Weston, Bath, UK.
Millar
A B
AB
D000368:Aged; D000804:Angiotensin II; D057911:Angiotensin Receptor Antagonists; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001168:Arthritis / Q000139:chemically induced* / Q000188:drug therapy / Q000276:immunology; D001323:Autoantibodies / Q000097:blood; D001327:Autoimmune Diseases / Q000097:blood / Q000139:chemically induced* / Q000188:drug therapy; D003599:Cytoskeleton / Q000276:immunology; D006801:Humans; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D011658:Pulmonary Fibrosis / Q000139:chemically induced* / Q000188:drug therapy / Q000276:immunology; D011928:Raynaud Disease / Q000139:chemically induced* / Q000188:drug therapy / Q000276:immunology; D012871:Skin Diseases / Q000139:chemically induced* / Q000188:drug therapy / Q000276:immunology; D013577:Syndrome; D013777:Tetrazoles / Q000009:adverse effects*; D014633:Valine / Q000009:adverse effects / Q000031:analogs & derivatives*; D000068756:Valsartan
D057911:Angiotensin Receptor Antagonists; D000893:Anti-Inflammatory Agents; D001323:Autoantibodies; D013777:Tetrazoles; D000804:Angiotensin II; D000068756:Valsartan; D011239:Prednisolone; D014633:Valine