[Reconstruction of the cervical esophagus using a revascularized ileal graft (experimental study)].
The clinic and histomorphology of the revascularized ileum autograft used for the reconstruction and/or replacing the cervical oesophagus in 76 adult mongrel dogs were examined from the 1st to 372nd postoperative days. In 46% of the cases complete recovery of autografts has been established. In 54% of the cases various complications were noticed-very long ischemia, necrosis and spontaneous detachment of the autografts injury of the superficial (endothelial) layer of blood vessels. Thrombosis of blood vessels, tissue haemorrhage, bleeding of the contact areas, wound infections, stenosis of the tubular autografts, unknown cases of abnormalities and mortality could also take place. There are a so-called split or detached contact within the oesophagus and the ileum graft as well as a lowering and enlargement of the villi, atypical crypts, partial replacement of the epithelium columnar cells with goblet cells, inflammatory lymphocytic infiltration of propria and epithelium, high phagocytic activity of the macrophages. The transplant changes can be more rapid if the defect of the cervical oesophagus is filled with a small intestine patch. At the junction of the morphological picture a strong hypo- and atrophy can be observed as well as the destruction and irritation, complete replacement of the columnar cells with mucous cells. In the so-called resorptive contact typical epitheliocytes have been replaced by a polymorphic cell mass. Acute inflammatory infiltration penetrated regionally all over the transplant. The simple columnar epithelium of the ileus transplant has been replaced by the non-keratinized stratified squamous epithelium.
Khussar
Iu P
IuP
Milenin
O V
OV
Tiunder
E O
EO
Sillakivi
T K
TK
Pille
A P
AP
Khussar
P Iu
PIu
D000714:Anastomosis, Surgical / Q000379:methods; D000818:Animals; D001158:Arteries / Q000601:surgery; D004285:Dogs; D004944:Esophagoplasty / Q000295:instrumentation / Q000379:methods*; D004947:Esophagus / Q000098:blood supply; D005500:Follow-Up Studies; D006085:Graft Survival; D007082:Ileum / Q000098:blood supply / Q000637:transplantation*; D008866:Microsurgery / Q000295:instrumentation / Q000379:methods; D013536:Suture Techniques; D013997:Time Factors; D014680:Veins / Q000601:surgery