title: Surgical treatment of invasive penile cancer--the Heidelberg experience from 1968 to 1994.
abstract: OBJECTIVE
  This study was performed to establish oncological guidelines for the surgical treatment of invasive penile cancer.
  
  
  METHODS
  The medical records of 51 patients with invasive penile cancer seen between 1968 and 1994 were reviewed in respect to treatment and long-term outcome.
  
  
  RESULTS
  For stage T1 tumors treated with organ-preserving procedures the local recurrence rats was 56%, whereas no patient experienced a local recurrence after partial amputation. For stage T2 tumors, local recurrence rate was 100% (organ preservation) versus 20% (amputative procedures). There was no significant difference related to regional recurrence between surveillance, inguinal radiation and lymphadenectomy for stage N0 tumors. For N+ stages, survival was related to the extent of inguinal metastasis after dissection (5-year survival rate for N1: 71 vs. 33% for N2/3).
  
  
  CONCLUSIONS
  Organ-preserving procedures include a high risk of local and regional recurrence. Adjuvant regional lymphadenectomy seems beneficial only in patients with solitary metastasis.
authors.affiliation: Department of Urology, Ruprecht Karls University, Heidelberg, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Brkovic
authors.forename: T
authors.initials: T
authors.lastname: Kälble
authors.forename: J
authors.initials: J
authors.lastname: Dörsam
authors.forename: S
authors.initials: S
authors.lastname: Pomer
authors.forename: C
authors.initials: C
authors.lastname: Lötzerich
authors.forename: R
authors.initials: R
authors.lastname: Banafsche
authors.forename: G
authors.initials: G
authors.lastname: Riedasch
authors.forename: G
authors.initials: G
authors.lastname: Staehler
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005500:Follow-Up Studies; D017408:Guidelines as Topic; D006801:Humans; D008137:Longitudinal Studies; D008197:Lymph Node Excision; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local; D010412:Penile Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D015996:Survival Rate