title: Decreased anterior cingulate gyrus metabolic rate in schizophrenia.
abstract: OBJECTIVE
  This study examined glucose metabolism in the anterior and posterior cingulate cortex in schizophrenia.
  
  
  METHODS
  Fifty unmedicated male schizophrenic patients and 24 normal men were studied with positron emission tomography.
  
  
  RESULTS
  Compared with the normal men, the schizophrenic patients had lower relative metabolic rates in the anterior cingulate and higher rates in the posterior cingulate.
  
  
  CONCLUSIONS
  The findings suggest hypofunction in the anterior cingulate cortex in schizophrenia.
authors.affiliation: Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029-6574, USA.
authors.forename: M M
authors.initials: MM
authors.lastname: Haznedar
authors.forename: M S
authors.initials: MS
authors.lastname: Buchsbaum
authors.forename: C
authors.initials: C
authors.lastname: Luu
authors.forename: E A
authors.initials: EA
authors.lastname: Hazlett
authors.forename: B V
authors.initials: BV
authors.lastname: Siegel
authors.forename: J
authors.initials: J
authors.lastname: Lohr
authors.forename: J
authors.initials: J
authors.lastname: Wu
authors.forename: R J
authors.initials: RJ
authors.lastname: Haier
authors.forename: W E
authors.initials: WE
authors.lastname: Bunney
mesh_terms: D000293:Adolescent; D000328:Adult; D003847:Deoxyglucose / Q000031:analogs & derivatives; D019788:Fluorodeoxyglucose F18; D005947:Glucose / Q000378:metabolism*; D006179:Gyrus Cinguli / Q000000981:diagnostic imaging / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012559:Schizophrenia / Q000000981:diagnostic imaging / Q000378:metabolism*; D014055:Tomography, Emission-Computed
chemical_list: D019788:Fluorodeoxyglucose F18; D003847:Deoxyglucose; D005947:Glucose