title: The central role of dietary fat, not carbohydrate, in the insulin resistance syndrome.
abstract: Compared with a diet high in total and saturated fat, a high carbohydrate diet improves insulin sensitivity and lipid levels. Recent studies have shown that subjects on an ad-lib low fat, high carbohydrate diet lose weight and, therefore, may have even greater improvement in the metabolic disturbances of the insulin resistance syndrome.
authors.affiliation: University of Washington, Division of Metabolism, Endocnnology and Nutrition, Seattle 98195, USA.
authors.forename: J Q
authors.initials: JQ
authors.lastname: Purnell
authors.forename: J D
authors.initials: JD
authors.lastname: Brunzell
mesh_terms: D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D004041:Dietary Fats / Q000008:administration & dosage*; D002149:Energy Intake; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood; D007333:Insulin Resistance; D008297:Male; D009765:Obesity / Q000178:diet therapy* / Q000378:metabolism
chemical_list: D004040:Dietary Carbohydrates; D004041:Dietary Fats