Heterogeneity of AMPA receptors in the dorsal column nuclei of the rat.
We have combined immunocytochemistry with retrograde tracing to demonstrate that projecting neurons in the gracile and cuneate nuclei express predominantly the GluR3 subunit of the AMPA receptor while interneurons in these nuclei express predominantly the GluR1 subunit. Interneurons expressing the GluR2 subunit are also present. It is speculated that the two classes of interneurons may release different inhibitory transmitters.
Popratiloff
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A
Department of Cell Biology and Anatomy, University of North Carolina at Chapel Hill, 27599, USA. poprat@med.unc.edu
Rustioni
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A
Weinberg
R J
RJ
D000818:Animals; D001370:Axonal Transport; D007150:Immunohistochemistry; D007395:Interneurons / Q000166:cytology; D008526:Medulla Oblongata / Q000033:anatomy & histology* / Q000166:cytology; D009474:Neurons / Q000166:cytology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D018091:Receptors, AMPA / Q000032:analysis*
D018091:Receptors, AMPA; C104723:glutamate receptor ionotropic, AMPA 3; C104722:glutamate receptor ionotropic, AMPA 2