[Primary biliary cirrhosis (PBC)-CREST overlap syndrome complicated with Sjögren's syndrome].
We reported two sisters of primary biliary cirrhosis (PBC)-CREST overlap syndrome complicated with Sjögren's syndrome (SS). Both patients had Raynaud's phenomenon, sclerodactylia, telangiectasia, chronic sialoadenitis, chronic nonsuppurative destructive cholangitis by liver biopsy and were positive for anti-centromere antibodies. This is the first report of two sisters of PBC-CREST overlap syndrome complicated with SS.
Akiyama
Y
Y
Second Department of Internal Medicine, Saitama Medical School.
Suzuki
T
T
Tanaka
M
M
Fujimaki
T
T
Asaoka
T
T
Kobayashi
K
K
Ohno
S
S
Imai
F
F
Matuo
H
H
D001323:Autoantibodies / Q000032:analysis; D017675:CREST Syndrome / Q000150:complications* / Q000235:genetics; D002503:Centromere / Q000276:immunology; D005192:Family Health; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000150:complications* / Q000235:genetics; D008875:Middle Aged; D008928:Mitochondria / Q000276:immunology; D012859:Sjogren's Syndrome / Q000150:complications* / Q000235:genetics
D001323:Autoantibodies