title: Exploring postinfarction reentrant ventricular tachycardia with entrainment mapping.
abstract: Ventricular tachycardia late after myocardial infarction is usually due to reentry in the infarct region. These reentry circuits can be large, complex and difficult to define, impeding study in the electrophysiology laboratory and making catheter ablation difficult. Pacing through the electrodes of the mapping catheter provides a new approach to mapping. When pacing stimuli capture the effects on the tachycardia depend on the location of the pacing site relative to the reentry circuit. The effects observed allow identification of various portions of the reentry circuit, without the need for locating the entire circuit. Isthmuses where relatively small lesions produced by radiofrequency catheter ablation can interrupt reentry can often be identified. A classification that divides reentry circuits into one or more functional components helps to conceptualize the reentry circuit and predicts the likelihood that heating with radiofrequency current will terminate tachycardia. These methods are helping to define human reentry circuits.
authors.affiliation: Department of medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 12115, USA. WGSTEVENSO@BICS.BWH.HARVARD.EDU
authors.forename: W G
authors.initials: WG
authors.lastname: Stevenson
authors.forename: P L
authors.initials: PL
authors.lastname: Friedman
authors.forename: P T
authors.initials: PT
authors.lastname: Sager
authors.forename: L A
authors.initials: LA
authors.lastname: Saxon
authors.forename: D
authors.initials: D
authors.lastname: Kocovic
authors.forename: T
authors.initials: T
authors.lastname: Harada
authors.forename: I
authors.initials: I
authors.lastname: Wiener
authors.forename: H
authors.initials: H
authors.lastname: Khan
mesh_terms: D002304:Cardiac Pacing, Artificial / Q000379:methods*; D017115:Catheter Ablation; D004562:Electrocardiography; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications*; D017180:Tachycardia, Ventricular / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology / Q000601:surgery