Genetically determined leukotriene B4 production is not required for cytotoxic effector cell development during allograft rejection.
Gignac
M R
MR
Division of Urologic Surgery/Renal Transplantation, University of Pittsburgh Medical Center, Pennsylvania, USA.
Chatlos
L J
LJ
Hoffman
R A
RA
Gritsch
H A
HA
Jordan
M L
ML
D000818:Animals; D001094:Arachidonate 5-Lipoxygenase / Q000235:genetics* / Q000378:metabolism*; D000001:Calcimycin / Q000494:pharmacology; D003433:Crosses, Genetic; D003602:Cytotoxicity, Immunologic; D006084:Graft Rejection / Q000276:immunology*; D007975:Leukotriene B4 / Q000096:biosynthesis*; D008070:Lipopolysaccharides / Q000494:pharmacology; D017710:Lymphocyte Transfusion; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology; D051379:Mice; D008810:Mice, Inbred C57BL; D018345:Mice, Knockout; D013154:Spleen / Q000166:cytology* / Q000276:immunology; D014184:Transplantation, Homologous / Q000276:immunology*; D014185:Transplantation, Isogeneic / Q000276:immunology
D008070:Lipopolysaccharides; D007975:Leukotriene B4; D000001:Calcimycin; D001094:Arachidonate 5-Lipoxygenase