title: The sequence of the Orgyia pseudotsugata multinucleocapsid nuclear polyhedrosis virus genome.
abstract: The nucleotide sequence of the Orgyia pseudotsugata multinucleocapsid nuclear polyhedrosis virus (OpMNPV) genome was completed and analyzed. It is composed of 131,990 bases with a G + C content of 55% and contains 152 putative genes of 150 nucleotides or greater. Major differences in gene content and arrangement between OpMNPV and the Autographa californica MNPV were found. These include the presence in OpMNPV of three complete iap gene homologs, two conotoxin gene homologs, two protein tyrosine phosphatase homologs, and genes encoding homologs of dUTPase and the large and small subunits of ribonucleotide reductase. Seven major intergenic repeated regions were identified. Five of these are homologous regions that are related to similar regions from other baculoviruses.
authors.affiliation: Department of Agricultural Chemistry, Oregon State University, Corvallis 97331-7301, USA.
authors.forename: C H
authors.initials: CH
authors.lastname: Ahrens
authors.forename: R L
authors.initials: RL
authors.lastname: Russell
authors.forename: C J
authors.initials: CJ
authors.lastname: Funk
authors.forename: J T
authors.initials: JT
authors.lastname: Evans
authors.forename: S H
authors.initials: SH
authors.lastname: Harwood
authors.forename: G F
authors.initials: GF
authors.lastname: Rohrmann
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D004279:DNA, Viral; D005814:Genes, Viral; D016679:Genome, Viral; D006801:Humans; D008969:Molecular Sequence Data; D009036:Moths / Q000821:virology*; D017924:Nucleopolyhedroviruses / Q000235:genetics*; D016366:Open Reading Frames; D011755:Pyrophosphatases / Q000235:genetics; D012091:Repetitive Sequences, Nucleic Acid; D012264:Ribonucleotide Reductases / Q000235:genetics; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
chemical_list: D004279:DNA, Viral; D012264:Ribonucleotide Reductases; D011755:Pyrophosphatases; C020020:dUTP pyrophosphatase