title: [Hymenoptera venom allergy].
abstract: In the light of two case reports we summarize the clinical presentation, classification, diagnosis and therapy of hymenoptera sting allergy. Clinically, large local reactions are distinguished from systemic allergic reactions. The latter are divided into four degrees of severity as defined by H.L. Mueller. Diagnosis is based primarily on the history. Detection of venom specific IgE-antibodies and/or positive venom skin tests confirm the diagnosis and are helpful for identification of the responsible insect. All patients should be equipped with an emergency kit (antihistamine, corticosteroid). In the presence of a history of systemic allergic reactions, adrenaline must be added. For highly exposed patients and those with a history of threatening reactions, specific immunotherapy is recommended. Most patients are fully protected by this treatment.
authors.affiliation: Allergielabor, Zieglerspital Bern.
authors.forename: P
authors.initials: P
authors.lastname: Meier
authors.forename: U
authors.initials: U
authors.lastname: Müller
mesh_terms: D000322:Adrenergic Agonists / Q000627:therapeutic use; D000328:Adult; D000707:Anaphylaxis / Q000209:etiology* / Q000628:therapy; D000818:Animals; D001516:Bees; D004837:Epinephrine / Q000627:therapeutic use; D005260:Female; D005440:Fluid Therapy; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D007299:Insect Bites and Stings / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010353:Patient Education as Topic; D013256:Steroids / Q000627:therapeutic use; D014863:Wasps
chemical_list: D000322:Adrenergic Agonists; D006634:Histamine H1 Antagonists; D013256:Steroids; D004837:Epinephrine