title: Unilateral cryptorchidism corrected in prepubertal age: evaluation of sperm parameters, hormones, and antisperm antibodies in adult age.
abstract: OBJECTIVE
  To evaluate whether prepubertal orchidopexy for unilateral cryptorchidism can reduce adult dysspermia.
  
  
  METHODS
  Patient follow-up comparison with control groups.
  
  
  METHODS
  Surgical and endocrinologic sections of a children's hospital and a university infertility-care center.
  
  
  METHODS
  Seventy-one patients with unilateral cryptorchidism who underwent orchidopexy in prepubertal age (6.4 +/- 2.8 years) were followed up as adults (20.0 +/- 2.8 years).
  
  
  METHODS
  Patients underwent testicular examination and hormonal evaluation, 49 of these had semen analysis and antisperm antibody tests. Semen results were compared with those of two age-matched control groups: a group of 20 healthy, randomly selected subjects and a group of 20 patients operated on in postpubertal age for cryptorchidism.
  
  
  RESULTS
  Unilateral reduced testis size was found in 30.1% of patients, eight patients had a low LH level, eight had a low T level, and none had abnormal FSH values. Antisperm antibodies were found in 1 of 49 cases. Cluster analysis of sperm parameters showed that the mean values of patients were worse than those of the healthy controls but better than those of the subjects operated on in postpubertal age.
  
  
  CONCLUSIONS
  This study indicates that prepubertal orchidopexy can given better results than postpubertal correction.
authors.affiliation: University of Rome La Sapienza, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Lenzi
authors.forename: L
authors.initials: L
authors.lastname: Gandini
authors.forename: F
authors.initials: F
authors.lastname: Lombardo
authors.forename: F
authors.initials: F
authors.lastname: Dondero
authors.forename: F
authors.initials: F
authors.lastname: Culasso
authors.forename: F
authors.initials: F
authors.lastname: Ferro
authors.forename: P
authors.initials: P
authors.lastname: Cambiaso
authors.forename: P
authors.initials: P
authors.lastname: Caione
authors.forename: M
authors.initials: M
authors.lastname: Cappa
mesh_terms: D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D003456:Cryptorchidism / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D011627:Puberty; D013094:Spermatozoa / Q000276:immunology* / Q000502:physiology*; D013737:Testis / Q000473:pathology; D013739:Testosterone / Q000097:blood
chemical_list: D001323:Autoantibodies; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone