[Study by NMR of the modifications of brain lipid composition related to the tumor processes].
1H, 13C, 31P and 14N NMR spectroscopies were used to investigate the lipid composition of brain tumors (GL6 glioma) in rats, by comparison with controlateral hemispheres. Comparative indexes derived from NMR signal intensities were used to establish the statistical analysis. It was found that sterol metabolism and sphingolipid/glycerolipids ratio are significantly modified when a tumor is present.
Debouzy
J C
JC
CRSSA, Service de Biophysique, La Tronche.
Fauvelle
F
F
Fouilhe
N
N
Sam-Lai
E
E
Nemoz
C
C
Girault
L
L
Mazet
L
L
D000818:Animals; D001923:Brain Chemistry; D001932:Brain Neoplasms / Q000737:chemistry*; D005910:Glioma / Q000737:chemistry*; D008055:Lipids / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D051381:Rats; D017207:Rats, Sprague-Dawley
D008055:Lipids