title: Unusual polyp-like structures in lobular panniculitis of a patient with Behçet's disease.
abstract: Unusual histopathologic structures were observed in lobular panniculitis of a patient with Behçet's disease. These were polyp-like in shape and protruded into cavities made of lysed fat cells. Various stages of development were observed. To determine the origin of cells making up these structures, we applied various histochemical and immunohistochemical techniques and found the cells to be histiocytes (macrophages) engaged in phagocytizing degenerated fat cells and cell membranes which had formed into membranocystic lesions.
authors.affiliation: Department of Dermatology, Kagoshima University Faculty of Medicine, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Ohtake
authors.forename: T
authors.initials: T
authors.lastname: Kanekura
authors.forename: K
authors.initials: K
authors.lastname: Kawamura
authors.forename: T
authors.initials: T
authors.lastname: Kanzaki
mesh_terms: D000273:Adipose Tissue / Q000473:pathology; D000368:Aged; D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D001528:Behcet Syndrome / Q000473:pathology*; D019070:Cell Lineage; D002462:Cell Membrane / Q000648:ultrastructure; D006644:Histiocytes / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D006820:Hyaluronic Acid / Q000032:analysis; D007150:Immunohistochemistry; D008264:Macrophages / Q000473:pathology; D008297:Male; D009113:Muramidase / Q000032:analysis; D015434:Panniculitis / Q000473:pathology*; D010587:Phagocytosis; D000514:alpha 1-Antichymotrypsin / Q000032:analysis; D000097382:CD68 Molecule
chemical_list: D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D006820:Hyaluronic Acid; D009113:Muramidase; D000514:alpha 1-Antichymotrypsin; C067980:CD68 antigen, human; D000097382:CD68 Molecule