title: Proton MR spectroscopy in Coats disease.
abstract: We describe a case of acute left-sided visual loss in a 4-year-old boy. CT showed hyperdense retinal detachment with a tiny calcification, and MR imaging showed subretinal hyperintensity on both T1- and T2-weighted images. Proton MR spectroscopy showed a large peak between 1 and 1.6 ppm that we believe corresponds mainly to lipids, which are characteristic of the exudate present in Coats disease.
authors.affiliation: Department of Radiology, University of North Carolina, School of Medicine, Chapel Hill 27599, USA.
authors.forename: L
authors.initials: L
authors.lastname: Eisenberg
authors.forename: M
authors.initials: M
authors.lastname: Castillo
authors.forename: L
authors.initials: L
authors.lastname: Kwock
authors.forename: S K
authors.initials: SK
authors.lastname: Mukherji
authors.forename: D K
authors.initials: DK
authors.lastname: Wallace
mesh_terms: D001813:Blood-Retinal Barrier; D002114:Calcinosis / Q000175:diagnosis*; D002675:Child, Preschool; D005122:Exudates and Transudates / Q000378:metabolism; D005500:Follow-Up Studies; D006801:Humans; D050356:Lipid Metabolism; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D011522:Protons; D012163:Retinal Detachment / Q000175:diagnosis*; D012164:Retinal Diseases / Q000175:diagnosis*; D013285:Strabismus / Q000175:diagnosis; D013684:Telangiectasis / Q000175:diagnosis; D014057:Tomography, X-Ray Computed; D014786:Vision Disorders / Q000175:diagnosis*
chemical_list: D011522:Protons