title: [Cerebrovascular accident and aortic thrombosis in a patient with protein S deficiency].
abstract: The authors report the case of a 50 year old man admitted to hospital with a right hemiplegia and aphasia of sudden onset in whom embolic fragments were found in the left mid and anterior cerebral artery territories at left carotid angiography : transoesophageal echocardiography demonstrated a protrusive plaque of atherosclerosis in the ascending aorta and a pediculated thrombosis in the descending aorta. Biological investigations revealed a protein S level of 3% (normal : 70-140%). This case illustrates the acute development of a thromboembolic phenomenon originating from the aortic arch in a patient with a coagulation defect.
authors.affiliation: Service de soins intensifs medicaux, department de médecine interne, Liège, Belgique.
authors.forename: B
authors.initials: B
authors.lastname: Lambermont
authors.forename: A
authors.initials: A
authors.lastname: Ghuysen
authors.forename: R
authors.initials: R
authors.lastname: Marcelle
authors.forename: L
authors.initials: L
authors.lastname: Pierard
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D001012:Aorta, Abdominal / Q000000981:diagnostic imaging; D001161:Arteriosclerosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D002533:Cerebral Angiography; D017548:Echocardiography, Transesophageal; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D018455:Protein S Deficiency / Q000150:complications* / Q000175:diagnosis; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants; D006493:Heparin