[Collagen membranes of increased absorption as carriers of antiseptics].
Collagen membranes of increased absorption were prepared by incubation in the acidic solutions and lyophilization. The organic acids and hydrochloric acid solutions were used for this purpose. The membranes incubated in 2% citric acid possessed of highest absorption. Microdressings containing povidone-iodine or chlorhexidine glycerin solution were prepared using the collagen membranes of increased absorption. The microdressings were packed into envelopes made of laminated aluminium foil; they were stabile for eight weeks concerning their antibacterial activity. After implantation beneath mouse skin the dressings did not cause inflammation. Such dressings may be useful in a treatment of ulcers, superficial burns and chronic granulated wounds.
Antiszko
M
M
Wojskowy Instytut Higieny i Epidemiologii w Warszawie.
Grzybowski
J
J
Tederko
A
A
Braczko
M
M
D000042:Absorption; D000818:Animals; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000737:chemistry*; D001458:Bandages; D001672:Biocompatible Materials; D002710:Chlorhexidine / Q000737:chemistry; D003094:Collagen / Q000737:chemistry*; D004337:Drug Carriers; D004343:Drug Implants; D004355:Drug Stability; D051379:Mice; D011206:Povidone-Iodine / Q000737:chemistry; D012996:Solutions
D000891:Anti-Infective Agents, Local; D001672:Biocompatible Materials; D004337:Drug Carriers; D004343:Drug Implants; D012996:Solutions; D011206:Povidone-Iodine; D003094:Collagen; D002710:Chlorhexidine