Normal human polyclonal immunoglobulins for intravenous use contain anti-idiotypes against natural xenophile antibodies and prolong discordant xenograft survival.
Schussler
O
O
INSERM U430, Hopital Broussais, Paris, France.
Latremouille
C
C
Genevaz
D
D
Carpentier
A
A
Glotz
D
D
D000818:Animals; D000888:Antibodies, Anti-Idiotypic; D000910:Antibodies, Heterophile; D001011:Aorta; D017690:Cell Transplantation; D002478:Cells, Cultured; D004730:Endothelium, Vascular / Q000166:cytology* / Q000276:immunology; D005434:Flow Cytometry; D006085:Graft Survival; D006168:Guinea Pigs; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism*; D007075:Immunoglobulin M / Q000378:metabolism*; D016756:Immunoglobulins, Intravenous / Q000494:pharmacology*; D051381:Rats; D012044:Regression Analysis; D014183:Transplantation, Heterologous
D000888:Antibodies, Anti-Idiotypic; D000910:Antibodies, Heterophile; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D016756:Immunoglobulins, Intravenous