title: The impact of ultrasound scanning in the staging and follow-up of patients with clinical stage I cutaneous melanoma.
abstract: In 85 patients with intermediate to high risk cutaneous melanoma, concomitant palpation and ultrasound scanning (US) of the axillary and inguinal sites were performed in order to detect any locoregional lymph node metastases at pre-operative staging and postoperative monitoring. At 12 months follow-up, US identified 12 out of 13 (92%) histologically proven metastases, while palpation indicated metastatic disease in only 3 (23%) patients. Metastases were intranodal in 6 out of 12 cases detected with US, and extranodal in all the 3 cases identified by palpation, thus confirming that US is more effective than palpation in the early detection of lymph node metastases from melanoma. US was also more effective in discriminating all non-neoplastic lymph nodes: its overall specificity was 100% versus 85% for palpation. Thus, when carried out by well-trained radiologists, US is a very useful diagnostic tool for the surgical oncologist dealing with melanoma patients.
authors.affiliation: Istituto di Clinica Chirurgica II, Università di Padova, Italy.
authors.forename: C R
authors.initials: CR
authors.lastname: Rossi
authors.forename: A
authors.initials: A
authors.lastname: Seno
authors.forename: A
authors.initials: A
authors.lastname: Vecchiato
authors.forename: M
authors.initials: M
authors.lastname: Foletto
authors.forename: A
authors.initials: A
authors.lastname: Tregnaghi
authors.forename: A
authors.initials: A
authors.lastname: De Candia
authors.forename: L
authors.initials: L
authors.lastname: Rubaltelli
authors.forename: C
authors.initials: C
authors.lastname: Montesco
authors.forename: M
authors.initials: M
authors.lastname: Lise
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001365:Axilla; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007264:Inguinal Canal; D008207:Lymphatic Metastasis; D008297:Male; D008545:Melanoma / Q000000981:diagnostic imaging* / Q000556:secondary*; D008875:Middle Aged; D009367:Neoplasm Staging; D010173:Palpation; D012680:Sensitivity and Specificity; D012878:Skin Neoplasms / Q000473:pathology*; D014463:Ultrasonography