title: [A case of primary malignant melanoma of the esophagus].
abstract: A case of primary and malignant melanoma of the esophagus was reported. A 64-year-old male complaining of discomfort of anterior chest pain was admitted to our hospital for operation. Findings of upper G-1 X-ray and endoscopic examination revealed suspiciously malignant melanoma. Subtotal thoracic esophagectomy with R III dissection was performed. Operative findings included A0 N2 Pl0 M0 Stage III. Macroscopically it showed black-grayish colored polypoid tumors, 7 cm in size. The typical finding of junctional activity adjacent to the tumor mass and melanocytes were microscopically found. The patient received postoperative systemic chemotherapy, but was died of multiple liver and bone metastases 125 days after surgery. Malignant melanoma of the esophagus has extremely poor prognosis and none of effective therapies has been reported.
authors.affiliation: Department of Surgery, Kin-Ikyo Chuo Hospital, Sapporo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Ishigooka
authors.forename: S
authors.initials: S
authors.lastname: Yamasaki
authors.forename: M
authors.initials: M
authors.lastname: Hirao
authors.forename: S
authors.initials: S
authors.lastname: Takanashi
authors.forename: J
authors.initials: J
authors.lastname: Iida
authors.forename: M
authors.initials: M
authors.lastname: Kashiyama
authors.forename: S
authors.initials: S
authors.lastname: Matuge
authors.forename: T
authors.initials: T
authors.lastname: Hara
authors.forename: H
authors.initials: H
authors.lastname: Kawashima
authors.forename: H
authors.initials: H
authors.lastname: Hatakeyama
authors.forename: Y
authors.initials: Y
authors.lastname: Hosokawa
authors.forename: T
authors.initials: T
authors.lastname: Tanabe
mesh_terms: D004938:Esophageal Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008545:Melanoma / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D011379:Prognosis