title: Oxygen transport to muscle during exercise in chronic congestive heart failure secondary to idiopathic dilated cardiomyopathy.
abstract: In chronic heart failure, oxygen delivery during exercise is impaired mainly because of failure of cardiac output to increase normally. Compensatory mechanisms are hemoglobin concentration increase, right-ward shift in the oxyhemoglobin dissociation curve, and blood flow redistribution from the nonexercising organs to the exercising muscles.
authors.affiliation: Istituto di Cardiologia dell' Università degli Studi, Centro Cardiologico Fondazione Monzino, IRCCS, Centro di Studio per le Ricerche Cardiovascolari del CNR, Milan, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Agostoni
authors.forename: K
authors.initials: K
authors.lastname: Wasserman
authors.forename: G B
authors.initials: GB
authors.lastname: Perego
authors.forename: G C
authors.initials: GC
authors.lastname: Marenzi
authors.forename: M
authors.initials: M
authors.lastname: Guazzi
authors.forename: E
authors.initials: E
authors.lastname: Assanelli
authors.forename: G
authors.initials: G
authors.lastname: Lauri
authors.forename: M D
authors.initials: MD
authors.lastname: Guazzi
mesh_terms: D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000150:complications / Q000378:metabolism*; D002908:Chronic Disease; D015444:Exercise; D006333:Heart Failure / Q000209:etiology / Q000378:metabolism*; D006801:Humans; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000378:metabolism*; D010101:Oxygen Consumption