title: The relationship between corneal eccentricity and improvement in visual acuity with orthokeratology.
abstract: BACKGROUND
  Due to the renewed attention given to reduction of myopia, interest in orthokeratology has dramatically increased. This study was performed to determine whether or not a predictor for orthokeratologic changes can be identified.
  
  
  METHODS
  Fifteen subjects enrolled in the study. For each subject, corneal eccentricity (e) was measured, subjective refraction and autorefraction were performed, and intraocular pressures were taken. Each subject was then fitted with a rigid contact lens for orthokeratology and followed for a minimum of 16 weeks. Eleven subjects completed the study.
  
  
  RESULTS
  No correlation between corneal eccentricity and improvement in visual acuity was found. Correlations were found between e and changes in subjective refraction, and between e and changes in autorefraction. There was also correlation between lower intraocular pressure and changes in subjective refraction, and between lower intraocular pressure and changes in autorefraction.
  
  
  CONCLUSIONS
  These findings suggest that corneal eccentricity and lower intraocular pressures may be predictors of orthokeratologic changes. A longitudinal study with a larger subject size will be needed to conclusively determine if these two measurements are predictors of orthokeratologic changes.
authors.forename: J J
authors.initials: JJ
authors.lastname: Joe
authors.forename: H J
authors.initials: HJ
authors.lastname: Marsden
authors.forename: T B
authors.initials: TB
authors.lastname: Edrington
mesh_terms: D003261:Contact Lenses; D003315:Cornea / Q000503:physiopathology*; D006801:Humans; D012030:Refractive Errors / Q000503:physiopathology* / Q000628:therapy*; D016896:Treatment Outcome; D014792:Visual Acuity