title: Isolated straight sinus and deep cerebral venous thrombosis: successful treatment with local infusion of urokinase. Case report.
abstract: A 23-year-old woman presented with headache and progressive lethargy. The diagnosis of isolated thrombosis of the straight sinus and of the deep cerebral venous system was established using cranial computerized tomography, magnetic resonance imaging, phase-contrast magnetic resonance venography, and cerebral angiography. Because of the rapid deterioration in the patient's clinical condition, the authors used direct transcatheter infusion of urokinase into the straight sinus. This treatment resulted in a successful outcome.
authors.affiliation: Department of Radiology, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, North Carolina, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Holder
authors.forename: D A
authors.initials: DA
authors.lastname: Bell
authors.forename: A L
authors.initials: AL
authors.lastname: Lundell
authors.forename: J L
authors.initials: JL
authors.lastname: Ulmer
authors.forename: S S
authors.initials: SS
authors.lastname: Glazier
mesh_terms: D000328:Adult; D002404:Catheterization; D002533:Cerebral Angiography; D002550:Cerebral Veins / Q000000981:diagnostic imaging / Q000473:pathology; D003392:Cranial Sinuses / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008279:Magnetic Resonance Imaging; D010690:Phlebography; D013382:Subtraction Technique; D013924:Thrombophlebitis / Q000175:diagnosis / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D014568:Urokinase-Type Plasminogen Activator