Rabies virus infection of cultured adult mouse dorsal root ganglion neurons.
An in vitro model of adult dorsal root ganglion neurons infection by rabies virus is described, Viral marked neurotropism is observed, and the percentage and the degree of infection of the neurons is higher than in non neuronal cells, even if neurons are the minority of the cells in the culture. The neuritic tree is also heavily infected by the virus.
Castellanos
J
J
Laboratorio de Neurobiología, Instituto Nacional de Salud, Bogotá, Colombia.
Hurtado
H
H
Arias
J
J
Velandia
A
A
D000818:Animals; D002478:Cells, Cultured; D005727:Ganglia, Spinal / Q000821:virology*; D051379:Mice; D009474:Neurons / Q000821:virology*; D011820:Rabies virus / Q000302:isolation & purification* / Q000502:physiology; D012306:Risk; D018523:Tropism; D014779:Virus Replication