title: Cytotoxic protein from human platelets.
abstract: The 14 kDa protein was purified from human platelets. It displays high cytotoxic activity to the human ACL cells at 10 M concentration (21.8+/-7.1%). Its N-terminal sequence is YAPQXQFGP-, being highly homologous to region 241-249 residues of the human Cls complement component.
authors.affiliation: Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow.
authors.forename: T S
authors.initials: TS
authors.lastname: Golubeva
authors.forename: V M
authors.initials: VM
authors.lastname: Paromov
authors.forename: A R
authors.initials: AR
authors.lastname: Tuguz
authors.forename: O Y
authors.initials: OY
authors.lastname: Chertov
authors.forename: M V
authors.initials: MV
authors.lastname: Kiselevsky
mesh_terms: D000595:Amino Acid Sequence; D001792:Blood Platelets / Q000737:chemistry*; D003602:Cytotoxicity, Immunologic; D003603:Cytotoxins / Q000097:blood*; D006801:Humans; D008969:Molecular Sequence Data; D011506:Proteins / Q000633:toxicity*
chemical_list: D003603:Cytotoxins; D011506:Proteins