Cytotoxic protein from human platelets.
The 14 kDa protein was purified from human platelets. It displays high cytotoxic activity to the human ACL cells at 10 M concentration (21.8+/-7.1%). Its N-terminal sequence is YAPQXQFGP-, being highly homologous to region 241-249 residues of the human Cls complement component.
Golubeva
T S
TS
Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow.
Paromov
V M
VM
Tuguz
A R
AR
Chertov
O Y
OY
Kiselevsky
M V
MV
D000595:Amino Acid Sequence; D001792:Blood Platelets / Q000737:chemistry*; D003602:Cytotoxicity, Immunologic; D003603:Cytotoxins / Q000097:blood*; D006801:Humans; D008969:Molecular Sequence Data; D011506:Proteins / Q000633:toxicity*
D003603:Cytotoxins; D011506:Proteins