Kupffer cells generate superoxide anions and modulate lipid peroxidation and mitochondrial proton ATP-ASE activity in the perfused rat liver after cold preservation.
Shibuya
H
H
Second Department of Surgery, Tohoku University School of Medicine, Sendai, Japan.
Ohkohchi
N
N
Seya
K
K
Satomi
S
S
D000241:Adenosine; D000493:Allopurinol; D000818:Animals; D003080:Cold Temperature; D005682:Gadolinium / Q000494:pharmacology; D005936:Glucans / Q000494:pharmacology; D005978:Glutathione; D007328:Insulin; D007728:Kupffer Cells / Q000187:drug effects / Q000502:physiology*; D015227:Lipid Peroxidation; D008099:Liver / Q000166:cytology / Q000502:physiology*; D008297:Male; D008930:Mitochondria, Liver / Q000201:enzymology*; D009926:Organ Preservation / Q000379:methods*; D019188:Organ Preservation Solutions; D006180:Proton-Translocating ATPases / Q000378:metabolism*; D011887:Raffinose; D051381:Rats; D011917:Rats, Inbred Lew; D015424:Reperfusion; D013481:Superoxides / Q000378:metabolism*; D013997:Time Factors
D005936:Glucans; D007328:Insulin; D019188:Organ Preservation Solutions; C055206:University of Wisconsin-lactobionate solution; D013481:Superoxides; D000493:Allopurinol; D005682:Gadolinium; D006180:Proton-Translocating ATPases; D005978:Glutathione; D000241:Adenosine; D011887:Raffinose; C038958:gadolinium chloride