title: Biodegradation of lantadene A, the pentacyclic triterpenoid hepatotoxin by Pseudomonas pickettii.
abstract: A bacterial strain capable of biodegradation of lantadene A (22 beta-angeloyloxy-3-oxoolean-12-en-28-oic acid) has been isolated from soil using lantadene A as the sole carbon source. The organism is rod shaped, Gram negative, motile and has been identified as Pseudomonas pickettii. This is the first report of the biodegradation of a pentacyclic triterpenoid.
authors.affiliation: Biochemistry Laboratory, Indian Veterinary Research Institute, Palampur, India.
authors.forename: O P
authors.initials: OP
authors.lastname: Sharma
authors.forename: R K
authors.initials: RK
authors.lastname: Dawra
authors.forename: A K
authors.initials: AK
authors.lastname: Datta
authors.forename: S S
authors.initials: SS
authors.lastname: Kanwar
mesh_terms: D000818:Animals; D001673:Biodegradation, Environmental; D001711:Biotransformation; D008099:Liver / Q000187:drug effects*; D015394:Molecular Structure; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity; D010947:Plants, Toxic; D011549:Pseudomonas / Q000254:growth & development / Q000302:isolation & purification / Q000378:metabolism*; D012988:Soil Microbiology; D014118:Toxins, Biological / Q000737:chemistry / Q000378:metabolism* / Q000633:toxicity*
chemical_list: D014118:Toxins, Biological; D009828:Oleanolic Acid; C019074:rehmannic acid