Problems and prospects of developing effective therapy for common cold viruses.
No effective treatment for common colds has yet been developed. Combination antiviral and anti-inflammatory therapies are the best hope for intervention after the onset of symptoms. Prophylaxis, especially in the form of vaccination, would have a major impact in disease prevention. These approaches offer new avenues for treating populations at risk and are of particular significance to those with asthma or chronic bronchitis.
Johnston
S L
SL
University Medicine, Southampton General Hospital, UK. slj1@soton.ac.uk
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D003139:Common Cold / Q000188:drug therapy* / Q000209:etiology / Q000517:prevention & control; D004205:Cromolyn Sodium / Q000627:therapeutic use; D015195:Drug Design; D015981:Epidemiologic Factors; D006801:Humans; D007249:Inflammation / Q000209:etiology; D007372:Interferons / Q000627:therapeutic use; D016376:Oligonucleotides, Antisense / Q000627:therapeutic use; D011480:Protease Inhibitors / Q000627:therapeutic use; D014614:Vaccines, Synthetic / Q000627:therapeutic use
D000305:Adrenal Cortex Hormones; D000893:Anti-Inflammatory Agents; D000998:Antiviral Agents; D016376:Oligonucleotides, Antisense; D011480:Protease Inhibitors; D014614:Vaccines, Synthetic; D007372:Interferons; D004205:Cromolyn Sodium