title: [Ambulatory treatment and prevention of priapism using alpha-agonists. Apropos of 172 cases].
abstract: From 1985 to 1995, 172 patients (149 on self intracavernous injection of vasoactive drugs, 16 with Sickle cell disease, 6 surgical patients under heparin therapy, and 1 after oral administration of trazodone), having experienced one or several episodes of priapism, lasting from 3 h to 8 days have been treated or submitted to self medication with alpha-agonist agents (eprephrine, phenylephrine or etilefrine) with an eventual drainage of the corporae. All episodes have disappeared and sexual function was preserved. A conservative treatment of priapism has been designed using corporal drainage and intracavernous etilefrine for acute priapism; as well as preventive treatment for those of the patients exposed to Sickle cell disease to avoid surgery and its frequent fribrotic sequelae, leading to impotence in 50% of the cases.
authors.affiliation: Centre d'Explorations et Traitements de l'Impuissance, Paris.
authors.forename: R
authors.initials: R
authors.lastname: Virag
authors.forename: D
authors.initials: D
authors.lastname: Bachir
authors.forename: J
authors.initials: J
authors.lastname: Floresco
authors.forename: F
authors.initials: F
authors.lastname: Galacteros
authors.forename: B
authors.initials: B
authors.lastname: Dufour
mesh_terms: D000293:Adolescent; D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage / Q000627:therapeutic use*; D000328:Adult; D000553:Ambulatory Care; D002648:Child; D002675:Child, Preschool; D004322:Drainage; D006801:Humans; D007267:Injections; D008297:Male; D011317:Priapism / Q000517:prevention & control / Q000628:therapy*
chemical_list: D000316:Adrenergic alpha-Agonists