title: [Treatment of nasal polyposis with systemic and local corticoids].
abstract: Surgical or medical treatment of nasal polyposis still is a challenge in otorhinolaryngology. A study was made of the effectiveness of combined local and systemic, steroid treatment. Thirty-seven patients with different grades of nasal polyposis received a combination of systemic (methylprednisolone oral 10 days) and local (inhaled budesonide, day 8 to day 28) steroids. Therapeutic effects were measured using nasal endoscopy with a four-stage system for grading nasal fossa involvement and a symptomatic scale of none, mild, moderate, and severe. The mean endoscopic score decreased from 1.14 on day 1 to 0.14 on day 28 and the symptom score from 2.8 to 1.2. The results show than nasal polyposis can be treated successfully with combined local and systemic steroid treatment.
authors.affiliation: Departamento de ORL, Universidad Ludwig-Maximilians de Munich.
authors.forename: G
authors.initials: G
authors.lastname: Rasp
authors.forename: J
authors.initials: J
authors.lastname: Bujía
mesh_terms: D000280:Administration, Inhalation; D000284:Administration, Oral; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D019819:Budesonide; D002985:Clinical Protocols; D005260:Female; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D009298:Nasal Polyps / Q000188:drug therapy*; D011282:Pregnenediones / Q000008:administration & dosage / Q000627:therapeutic use*; D012720:Severity of Illness Index
chemical_list: D000893:Anti-Inflammatory Agents; D011282:Pregnenediones; D019819:Budesonide; D008775:Methylprednisolone