title: [Experimental autoimmune labyrinthitis: evaluation of various models in guinea pigs].
abstract: Evidence of hearing loss in humans with systemic autoimmune disease has suggested the possibility of isolated forms of deafness originated by a autoimmune mechanism. Several authors reject McCabe's (1) proposed clinical description based mainly on response to treatment and have attempted to develop an animal model of autoimmune deafness. A comparative analysis was made of several experimental models of sensorineural hearing loss in guinea pigs developed in our laboratory for the study of this problem.
authors.affiliation: Servicio de ORL, Clínica Puerta de Hierro, Universidad Autónoma de Madrid.
authors.forename: J R
authors.initials: JR
authors.lastname: García-Berrocal
authors.forename: J
authors.initials: J
authors.lastname: Vicente
authors.forename: B
authors.initials: B
authors.lastname: Arellano
authors.forename: F
authors.initials: F
authors.lastname: González
authors.forename: R
authors.initials: R
authors.lastname: Ramírez-Camacho
mesh_terms: D000818:Animals; D015551:Autoimmunity; D004195:Disease Models, Animal; D005260:Female; D006168:Guinea Pigs; D006319:Hearing Loss, Sensorineural / Q000209:etiology; D007762:Labyrinthitis / Q000276:immunology*