title: Electrical stimulation on joint contracture: an experiment in rat model with direct current.
abstract: OBJECTIVE
  To examine whether electrical stimulation could decrease the degree of joint stiffness in a rat lower extremity model.
  
  
  METHODS
  Rat knee joints were surgically immobilized in a flexed position for 3 weeks. Two groups of rats were stimulated with 20 microA and 50 microA constant direct current. Another group had surgical intervention and sham electrodes without electricity. The hind leg was extirpated and prepared for a sample with the femur-knee joint-tibia unit. Recording the knee flexion angle with extension torque, the degree of joint contracture was assessed biomechanically by measuring the bone-joint-bone sample as a cantilever. Measurement was performed with (1) spectral analysis of transfer function measurement using random mechanical noise with frequency range from 1 to 50Hz, and (2) dynamic stiffness and loss tangent with steady-state sinusoidal excitation (11 and 35Hz).
  
  
  RESULTS
  The results showed that no significant difference or trend was found in vibration analysis among three groups. However, spectral analysis of transfer function measurement revealed more deformation against load, and more viscous nature in the stimulation groups, especially in low frequency band, than in the sham group.
  
  
  CONCLUSIONS
  Electrical stimulation with constant direct current has a possibility of reducing the degree of joint contracture.
authors.affiliation: Department of Physical Therapy, Tsukuba College of Technology, Ibaraki, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Akai
authors.forename: Y
authors.initials: Y
authors.lastname: Shirasaki
authors.forename: T
authors.initials: T
authors.lastname: Tateishi
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D003286:Contracture / Q000628:therapy*; D004195:Disease Models, Animal; D004599:Electric Stimulation Therapy; D006614:Hindlimb; D008297:Male; D051381:Rats; D017208:Rats, Wistar