Effect of chronic trypanosomiasis on the bioavailability of alpha-difluoromethylornithine (DFMO) after oral administration: pharmacokinetics study on DFMO plasma levels in infected and noninfected mice using a high-performance liquid chromatography assay.
Loiseau
P M
PM
Biologie et Contrôle des Organismes Parasites, Faculté de Pharmacie, Université de Paris XI, France.
Chauffert
O
O
Czok
M
M
D000818:Animals; D001682:Biological Availability; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D000518:Eflornithine / Q000097:blood / Q000493:pharmacokinetics*; D005260:Female; D051379:Mice; D014344:Trypanocidal Agents / Q000097:blood / Q000493:pharmacokinetics*; D014346:Trypanosoma brucei brucei; D014353:Trypanosomiasis, African / Q000378:metabolism*
D014344:Trypanocidal Agents; D000518:Eflornithine