title: Unusual atrial pro-arrhythmic effect of flecainide: a contemporary review.
abstract: The authors report the case of a patient with drug-resistant atrial fibrillation, who developed, for more than 2 hours, a well-tolerated attack of palpitations, after taking 500 mg of flecainide acetate. The Holter monitoring demonstrated atrial flutter with 1:1 AV conduction and a ventricular rate at 220 bpm. This atrial pro-arrhythmic effect is rare and the mechanism is discussed.
authors.affiliation: Division of Cardiology, Jolimont Hospital, Haine-Saint-Paul, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: De Meester
authors.forename: J P
authors.initials: JP
authors.lastname: Machiels
authors.forename: L
authors.initials: L
authors.lastname: Rousseau
authors.forename: R
authors.initials: R
authors.lastname: Luwaert
authors.forename: J M
authors.initials: JM
authors.lastname: Chaudron
mesh_terms: D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D001282:Atrial Flutter / Q000139:chemically induced*; D015716:Electrocardiography, Ambulatory; D005260:Female; D005424:Flecainide / Q000009:adverse effects*; D006801:Humans
chemical_list: D000889:Anti-Arrhythmia Agents; D005424:Flecainide