title: Leiomyosarcoma of the vagina.
abstract: Vaginal leiomyoma is uncommon and borderline leiomyoma of the vagina is an extreme rarity. Leiomyoma of the vagina may undergo malignant change to become borderline malignancy or leiomyosarcoma. A 38-year-old woman, complaining of foul vaginal discharge and dyspareunia with 2 months duration, underwent total excision of tumor. The removed tumor was diagnosed as borderline case of leiomyoma histologically. Unfortunately, she had tumor recurrence within 4 months. Thus, it was more likely that the primary diagnosis was incorrect and that the diagnosis leiomyosarcoma has been missed. She underwent total abdominal hysterectomy, bilateral salphingo-oophorectomy and total vaginectomy. The final diagnosis was leiomyosarcoma. Three months later tumor recurred again and re-excision followed by chemotherapy was performed. However, she died of her disease on her 5th month following three courses of chemotherapy.
authors.affiliation: Division of Gynecologic Oncology, Dr. Zekai Tahir Burak Women's Hospital, Ankara, Turkey.
authors.forename: O
authors.initials: O
authors.lastname: Cobanoğlu
authors.forename: C
authors.initials: C
authors.lastname: Gürkan Zorlu
authors.forename: Y
authors.initials: Y
authors.lastname: Ergun
authors.forename: L
authors.initials: L
authors.lastname: Kutluay
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D009364:Neoplasm Recurrence, Local; D012086:Reoperation; D014625:Vaginal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery