title: QEEG and neuropsychological profiles of patients prior to undergoing cardiopulmonary bypass surgical procedures.
abstract: Within our patient population undergoing cardiopulmonary bypass (CPB) surgery, evidence of pre-existing cortical dysfunction was highly prevalent, with 39.5% displaying QEEG and/or neuropsychological (NP) abnormality. These patients with pre-existing QEEG or NP abnormality were at increased risk for developing both short and long-term postoperative deficits in NP performance. Preoperative QEEG showed increased sensitivity and specificity over preoperative NP performance for predicting NP performance one week after surgery. One week after surgery NP deficits were quite common occurring in 40.6% of the patients. Two to three months after surgery evidence of continued NP performance deficits were still present in 28.1% of the patients. Preoperative NP performance predicted 3 month postoperative NP performance quite well, although preoperative QEEG proved equally effective.
authors.affiliation: Department of Anesthesia, Brigham and Women's Hospital, Boston, MA, USA.
authors.forename: L D
authors.initials: LD
authors.lastname: Gugino
authors.forename: R J
authors.initials: RJ
authors.lastname: Chabot
authors.forename: L S
authors.initials: LS
authors.lastname: Aglio
authors.forename: R
authors.initials: R
authors.lastname: Maddi
authors.forename: J
authors.initials: J
authors.lastname: Gosnell
authors.forename: S
authors.initials: S
authors.lastname: Aranki
mesh_terms: D006348:Cardiac Surgical Procedures; D002315:Cardiopulmonary Bypass / Q000009:adverse effects; D003072:Cognition Disorders / Q000175:diagnosis*; D001026:Coronary Artery Bypass; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011183:Postoperative Complications / Q000175:diagnosis; D011300:Preoperative Care; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted