title: Chronic urticaria associated with aseptic meningitis: an atypical urticarial vasculitis?
abstract: The patient was a 7-year-old girl with early onset urticarial cutaneous lesions and was later complicated with aseptic meningitis. Her skin lesions occurred in the infantile period and were diagnosed as urticaria, but did not disappear with antihistamines and were recurrent and persistent. In addition, she had experienced an episode of headache about once a month since 1991, when she was 4 years old, and was diagnosed as aseptic meningitis. All studies including skin biopsy for urticarial vasculitis (UV) and systemic lupus erythematosus (SLE) were negative except for the data from non-specific inflammations. A systemic corticosteroid therapy dramatically reduced her symptoms. An unusual clinical course for this patient is described. It might suggest that this case is a presentation of the disease entity of UV, chronic urticaria and possibly SLE. To our knowledge, a similar case has not been previously reported.
authors.affiliation: Department of Pediatrics, Hirosaki University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Tanaka
authors.forename: S
authors.initials: S
authors.lastname: Waga
authors.forename: Y
authors.initials: Y
authors.lastname: Kakizaki
authors.forename: K
authors.initials: K
authors.lastname: Sugimoto
authors.forename: K
authors.initials: K
authors.lastname: Nomura
authors.forename: M
authors.initials: M
authors.lastname: Yokoyama
mesh_terms: D002648:Child; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008582:Meningitis, Aseptic / Q000134:cerebrospinal fluid / Q000150:complications*; D012867:Skin / Q000473:pathology; D014581:Urticaria / Q000134:cerebrospinal fluid / Q000150:complications* / Q000473:pathology