title: Thiopurine biology and pharmacology.
authors.affiliation: Department of Pharmacology, Institute of Medical Biology, University of Tromsø, Norway.
authors.forename: J
authors.initials: J
authors.lastname: Aarbakke
authors.forename: G
authors.initials: G
authors.lastname: Janka-Schaub
authors.forename: G B
authors.initials: GB
authors.lastname: Elion
mesh_terms: D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use; D001379:Azathioprine / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D003001:Cloning, Molecular; D005838:Genotype; D006801:Humans; D007166:Immunosuppressive Agents / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology; D015122:Mercaptopurine / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use; D008780:Methyltransferases / Q000172:deficiency / Q000235:genetics* / Q000378:metabolism; D051379:Mice; D011110:Polymorphism, Genetic / Q000235:genetics; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000235:genetics / Q000378:metabolism; D011687:Purines / Q000737:chemistry / Q000378:metabolism*; D013329:Structure-Activity Relationship; D013866:Thioguanine / Q000378:metabolism / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000964:Antimetabolites, Antineoplastic; D007166:Immunosuppressive Agents; D011687:Purines; D015122:Mercaptopurine; D008780:Methyltransferases; C022745:thiopurine methyltransferase; D013866:Thioguanine; D001379:Azathioprine