[Organ-specific nodular pulmonary amyloidosis of the A lambda type in Sjogren syndrome].
The exclusive involvement of the lungs with A lambda-type amyloidosis in nodular dispositions in a case of Sjögren's syndrome is very rare. An immunoglobulin lambda-type light chain, benign, monoclonal gammopathy has been verified as the ethological cause. The urine concentration of paraproteins was below the detection limit of the common examination methods and could only be found immunoelectrophoretically in urine concentrated 100-200 fold. The question of a possible relationship with Sjögren's syndrome is being discussed.
Schneider
F
F
Rheumaklinik Oberammergau, Max-Planck-Institut für Biochemie Martinsried.
Linke
R P
RP
Albrecht
H J
HJ
D000682:Amyloid / Q000652:urine*; D000686:Amyloidosis / Q000175:diagnosis* / Q000276:immunology; D001707:Biopsy, Needle; D001853:Bone Marrow / Q000473:pathology; D005260:Female; D006801:Humans; D007122:Immunoelectrophoresis; D007147:Immunoglobulin Light Chains / Q000652:urine*; D007146:Immunoglobulin lambda-Chains / Q000652:urine*; D008168:Lung / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010265:Paraproteinemias / Q000175:diagnosis* / Q000652:urine; D010266:Paraproteins / Q000652:urine; D010950:Plasma Cells / Q000473:pathology; D012859:Sjogren's Syndrome / Q000175:diagnosis* / Q000276:immunology; D003074:Solitary Pulmonary Nodule / Q000175:diagnosis / Q000276:immunology; D014057:Tomography, X-Ray Computed
D000682:Amyloid; D007147:Immunoglobulin Light Chains; D007146:Immunoglobulin lambda-Chains; D010266:Paraproteins; C035222:amyloid protein AL