Gastric adenocarcinoma and low-grade B-cell lymphoma of mucosa-associated lymphoid tissue.
We describe the synchronous occurrence of gastric signet-ring cell adenocarcinoma and low-grade B-cell lymphoma of mucosa-associated lymphoid tissue in a patient with chronic gastritis and intestinal metaplasia. Histologic features of the mucosal inflammation, a follicular gastritis, were suggestive of a chronic Helicobacter pylori infection. Previous hypotheses concerning the relationship of long-standing gastritis and development of gastric carcinoma and lymphoma are supported by our findings.
Hardman
W J
WJ
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Ga 30322, USA.
Gal
A A
AA
Pascal
R R
RR
D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology; D002908:Chronic Disease; D005756:Gastritis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications* / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D013274:Stomach Neoplasms / Q000150:complications* / Q000473:pathology