title: Thermodynamics, molecules and the Gibbs conference.
abstract: Molecular concepts have been gradually incorporated into chemical thermodynamics. This is done by applying standard thermodynamics manipulations to systems which are restricted by the assumption of a specific molecular model or mechanism. Here we trace the development of this procedure and its applications from Avogadro's hypothesis to modern work on site-directed mutagenesis.
authors.affiliation: Institute of Molecular Biology, University of Oregon, Eugene 97403, USA. JOHN@JAS1.UOREGON.EDU
authors.forename: J A
authors.initials: JA
authors.lastname: Schellman
mesh_terms: D008956:Models, Chemical; D016297:Mutagenesis, Site-Directed; D013816:Thermodynamics