title: [Use of cefpirome in the treatment of patients with skin and soft tissue infections].
abstract: The efficacy of cefpirome was estimated in the treatment of 25 patients: 15 patients with pyo-necrotic wounds of the soft tissue of various genesis and localization and 10 patients with deep thermal burns involving 8 to 40 per cent of the body surface. The clinical and bacteriological efficacies of the treatment in the patients with the wound infection amounted to 100 and 80 per cent respectively. In the patients with the burn infection the respective values were 90 and 80 per cent. The drug tolerance was good. Adverse reactions were observed in 1 patient. Bolus intravenous administration of the drug was preferable by comparison with the injections.
authors.forename: V P
authors.initials: VP
authors.lastname: Iakovlev
authors.forename: L A
authors.initials: LA
authors.lastname: Blatun
authors.forename: M G
authors.initials: MG
authors.lastname: Krutikov
authors.forename: L S
authors.initials: LS
authors.lastname: Puchkova
authors.forename: G N
authors.initials: GN
authors.lastname: Izotova
authors.forename: A M
authors.initials: AM
authors.lastname: Svetukhin
authors.forename: A A
authors.initials: AA
authors.lastname: Alekseev
mesh_terms: D000293:Adolescent; D000328:Adult; D002056:Burns / Q000382:microbiology; D002511:Cephalosporins / Q000009:adverse effects / Q000627:therapeutic use*; D006801:Humans; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009336:Necrosis; D017192:Skin Diseases, Bacterial / Q000188:drug therapy* / Q000382:microbiology; D018461:Soft Tissue Infections / Q000188:drug therapy* / Q000382:microbiology / Q000473:pathology; D016896:Treatment Outcome; D014946:Wound Infection / Q000188:drug therapy* / Q000382:microbiology; D000097572:Cefpirome
chemical_list: D002511:Cephalosporins; D000097572:Cefpirome