title: [The pharmacodynamics of general anesthetics. The neurological and cardiovascular aspects].
abstract: General anaesthesia is defined as a state of pharmacological coma. After a brief review of the central neurotransmission, the active mechanisms of general anaesthesia are analysed, as a pharmacological basis for an adequate understanding of their effects and interactions, with special emphasis on the neurological and cardiovascular aspects.
authors.affiliation: Instituto Farmacologia, Faculdade Medicina de Lisboa.
authors.forename: F M
authors.initials: FM
authors.lastname: Vale
mesh_terms: D000759:Adjuvants, Anesthesia / Q000493:pharmacokinetics; D018681:Anesthetics, General / Q000493:pharmacokinetics* / Q000494:pharmacology; D018685:Anesthetics, Inhalation / Q000493:pharmacokinetics; D018686:Anesthetics, Intravenous / Q000493:pharmacokinetics; D000818:Animals; D002319:Cardiovascular System / Q000187:drug effects*; D004347:Drug Interactions; D006801:Humans; D009435:Synaptic Transmission / Q000187:drug effects*
chemical_list: D000759:Adjuvants, Anesthesia; D018681:Anesthetics, General; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous