Persistent JC virus (JCV) infection is demonstrated by continuous shedding of the same JCV strains.
The polyomavirus JC virus (JCV), the causative agent of progressive multifocal leukoencephalopathy, is ubiquitous in the human population, infecting children asymptomatically. JCV is often detected in normal renal tissue and in the urine of healthy individuals. We demonstrate that renal JCV represents that which persists after primary infection.
Kitamura
T
T
Department of Urology, Branch Hospital, Faculty of Medicine, University of Tokyo, Japan.
Sugimoto
C
C
Kato
A
A
Ebihara
H
H
Suzuki
M
M
Taguchi
F
F
Kawabe
K
K
Yogo
Y
Y
D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D007577:JC Virus / Q000302:isolation & purification*; D008297:Male; D008875:Middle Aged; D008969:Molecular Sequence Data; D027601:Polyomavirus Infections / Q000652:urine / Q000821:virology*; D014412:Tumor Virus Infections / Q000652:urine / Q000821:virology*