European Union System for the Evaluation of Substances (EUSES). Principles and structure.
In the European Union, Directive 92/32/EC and EC Council Regulation (EC) 793/93 require the risk assessment of new and existing substances, respectively. Principles for this risk assessment have been laid down, supported by a detailed package of Technical Guidance Documents. Against this background the European Union System for the Evaluation of Substances (EUSES) has been developed. This software can be used to carry out tiered risk assessments of increasing complexity on the basis of increasing data requirements. The exposure assessment, effects assessment and risk characterisation are carried out for environmental populations as well as for human beings, including workers, consumers and man exposed through the environment. EUSES is the result of a co-ordinated effort of EU Member States, the European Commission and the European Chemical Industry.
Vermeire
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TG
National Institute of Public Health and the Environment, RIVM, Bilthoven, The Netherlands.
Jager
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DT
Bussian
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Devillers
J
J
den Haan
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K
Hansen
B
B
Lundberg
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I
Niessen
H
H
Robertson
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S
Tyle
H
H
van der Zandt
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PT
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004781:Environmental Exposure; D004782:Environmental Health / Q000592:standards; D005062:European Union; D005506:Food Contamination; D017408:Guidelines as Topic; D015386:Hazardous Substances / Q000009:adverse effects*; D006801:Humans; D007391:International Cooperation; D016273:Occupational Exposure; D018570:Risk Assessment; D012984:Software; D012989:Soil Pollutants / Q000009:adverse effects; D014873:Water Pollutants / Q000009:adverse effects
D015386:Hazardous Substances; D012989:Soil Pollutants; D014873:Water Pollutants