Evaluation of the Kodak Surecell Chlamydia test for the laboratory diagnosis of adult inclusion conjunctivitis.
OBJECTIVE
The Kodak Surecell Chlamydia test, a rapid enzyme immunoassay, has been reported to be highly sensitive (93%) and specific (96%) for detecting chlamydial lipopolysaccharide antigen in conjunctival specimens from infants, but has not been evaluated previously in adult conjunctival specimens. This study was designed to determine the efficacy of the Kodak Surecell Chlamydia test for the laboratory diagnosis of adult inclusion conjunctivitis.


METHODS
Twenty Chlamydia culture-positive conjunctival specimens from adults (true-positives) and 20 true-negative specimens were tested with the Kodak Surecell Chlamydia test.


RESULTS
The Kodak Surecell Chlamydia test was 40% (8/20) sensitive, 100% (20/20) specific, and 70% (28/40) efficient.


CONCLUSIONS
This study indicates that the Kodak Surecell Chlamydia test, though highly specific, is less sensitive in its ability to diagnose chlamydial conjunctivitis in adults than has been reported previously in infants.
Tantisira
J G
JG
Department of Ophthalmology, University of Pittsburgh, PA, USA.
Kowalski
R P
RP
Gordon
Y J
YJ
D000328:Adult; D000942:Antigens, Bacterial / Q000032:analysis*; D002692:Chlamydia trachomatis / Q000276:immunology* / Q000302:isolation & purification; D003228:Conjunctiva / Q000382:microbiology; D003235:Conjunctivitis, Inclusion / Q000175:diagnosis* / Q000382:microbiology; D005189:False Positive Reactions; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008070:Lipopolysaccharides / Q000032:analysis*; D008297:Male; D011237:Predictive Value of Tests; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity
D000942:Antigens, Bacterial; D008070:Lipopolysaccharides; D011933:Reagent Kits, Diagnostic