Aeration-dependent changes in composition of the quinone pool in Escherichia coli. Evidence of post-transcriptional regulation of the quinone biosynthesis.
The aeration-dependent changes in content of various quinones in Escherichia coli were found to be unaffected by a prokaryotic translation inhibitor chloramphenicol. In addition, this process was shown to be completely intact in cells with mutated fnr, arc and appY loci. It is assumed that E. coli possesses a special system of oxygen-dependent post-transcriptional regulation of the quinone biosynthetic pathways.
Shestopalov
A I
AI
Department of Bioenergetics, Belozersky Institute of Physico-Chemical Biology, Moscow State University, Russia.
Bogachev
A V
AV
Murtazina
R A
RA
Viryasov
M B
MB
Skulachev
V P
VP
D000332:Aerobiosis; D000693:Anaerobiosis; D002701:Chloramphenicol / Q000494:pharmacology; D003573:Cytochrome b Group; D003580:Cytochromes / Q000378:metabolism; D045222:Electron Transport Chain Complex Proteins; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism*; D029968:Escherichia coli Proteins; D005838:Genotype; D010088:Oxidoreductases / Q000378:metabolism; D011809:Quinones / Q000302:isolation & purification / Q000378:metabolism*; D013045:Species Specificity; D014451:Ubiquinone / Q000378:metabolism; D014812:Vitamin K / Q000031:analogs & derivatives / Q000378:metabolism; D024482:Vitamin K 2 / Q000031:analogs & derivatives*
D003573:Cytochrome b Group; D003580:Cytochromes; D045222:Electron Transport Chain Complex Proteins; D029968:Escherichia coli Proteins; D011809:Quinones; D024482:Vitamin K 2; D014812:Vitamin K; D014451:Ubiquinone; C013917:demethylmenaquinone; D002701:Chloramphenicol; D010088:Oxidoreductases; C040077:cytochrome bd terminal oxidase complex, E coli