title: [Current trends in the diagnosis and therapy of colorectal cancer].
abstract: The report deals with the 30-year experience gained by the Department in the treatment of nearly 5,500 cases of tumors of large bowel. Radical surgery for colonic tumor was followed by lethality in 3.0 and 5-year survival-80.8%; rectal tumor resection-5.3 and 58.2%, respectively. Individually-tailored modalities have been devised for a spectrum of cases of colonic wall invasion and metastatic lesions in regional lymph nodes. A choice of sparing, extended and combined surgical procedures vis-a-vis these factors has been developed, the latter offering most advantage. Therapeutic strategies for hepatic metastasis have been worked out on individual basis.
authors.forename: N N
authors.initials: NN
authors.lastname: Simonov
authors.forename: A V
authors.initials: AV
authors.lastname: Guliaev
authors.forename: I V
authors.initials: IV
authors.lastname: Pravosudov
authors.forename: V K
authors.initials: VK
authors.lastname: Kovalev
authors.forename: V V
authors.initials: VV
authors.lastname: Korkhov
authors.forename: B V
authors.initials: BV
authors.lastname: Matveev
authors.forename: O R
authors.initials: OR
authors.lastname: Mel'nikov
authors.forename: E P
authors.initials: EP
authors.lastname: Rybin
authors.forename: D G
authors.initials: DG
authors.lastname: Ushveridze
authors.forename: A V
authors.initials: AV
authors.lastname: Shulepov
mesh_terms: D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D018572:Disease-Free Survival; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary / Q000628:therapy; D008207:Lymphatic Metastasis; D009361:Neoplasm Invasiveness; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome