title: Influence of acute cholecystitis on surgical strategy and outcome of inapparent carcinoma of the gallbladder: a report on two cases.
abstract: Unsuspected microscopic adenocarcinoma (T1) of the gallbladder was identified after surgery in two patients who underwent urgent open cholecystectomy for acute cholecystitis. In spite of the tumor being at an early stage both patients died after few months for local and disseminated tumor recurrence. The influence of the associated inflammatory disease of the gallbladder on the outcome of patients with inapparent gallbladder carcinoma is discussed and a more aggressive surgical strategy is suggested.
authors.affiliation: 1st Department of Surgery, La Sapienza University, Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Mingoli
authors.forename: S
authors.initials: S
authors.lastname: Civitelli
authors.forename: G
authors.initials: G
authors.lastname: Sgarzini
authors.forename: F
authors.initials: F
authors.lastname: Ciccarone
authors.forename: F
authors.initials: F
authors.lastname: Corzani
authors.forename: A
authors.initials: A
authors.lastname: Puggioni
authors.forename: C
authors.initials: C
authors.lastname: Modini
mesh_terms: D000208:Acute Disease; D000230:Adenocarcinoma / Q000601:surgery*; D000368:Aged; D002763:Cholecystectomy; D002764:Cholecystitis / Q000601:surgery*; D005260:Female; D005706:Gallbladder Neoplasms / Q000601:surgery*; D006801:Humans; D008875:Middle Aged