The effect of pamidronate on lumbar spine bone density and pain in osteoporosis secondary to systemic mastocytosis.
Three patients with osteoporosis secondary to systemic mastocytosis are described. With the exception of the typical rash of urticaria pigmentosa, spinal pain caused by osteoporosis was the most prominent symptom. Intermittent single i.v. infusions of pamidronate have controlled pain an improved lumbar spine bone density.
Marshall
A
A
Department of Rheumatology, Addenbrooke's Hospital, Cambridge.
Kavanagh
R T
RT
Crisp
A J
AJ
D000328:Adult; D015519:Bone Density / Q000187:drug effects* / Q000502:physiology; D004164:Diphosphonates / Q000494:pharmacology*; D005260:Female; D006801:Humans; D008159:Lumbar Vertebrae / Q000187:drug effects / Q000503:physiopathology; D008297:Male; D008415:Mastocytosis / Q000150:complications*; D008875:Middle Aged; D010024:Osteoporosis / Q000188:drug therapy* / Q000209:etiology* / Q000503:physiopathology; D010146:Pain / Q000188:drug therapy; D000077268:Pamidronate
D004164:Diphosphonates; D000077268:Pamidronate