Effect of vitamin D deficiency on electrocardiogram of rats.
Electrocardiograms (ECGs) were studied in rats fed vitamin D deficient diet for 12 weeks. The results indicated significant shortening of QT interval of ECG. Other intervals were normal when compared with age matched control rats. Heart/body weight ratio was significantly increased in vitamin D deficient group, which is an index of hypertrophy, with increased collagen fiber in the histology of the myocardium, inspite of normal serum calcium level. The results suggested a direct role of vitamin D in the regulation of cardiac functions.
Sood
S
S
Department of Physiology, Medical College, Rohtak, India.
Reghunandanan
R
R
Reghunandanan
V
V
Gopinathan
K
K
Sood
A K
AK
D000818:Animals; D004562:Electrocardiography; D006321:Heart / Q000503:physiopathology*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D014808:Vitamin D Deficiency / Q000503:physiopathology*