title: Orbital avitene granuloma formation after enucleation for intraocular retinoblastoma.
abstract: OBJECTIVE
  To report a case of orbital foreign body granuloma formation, mimicking tumor recurrence, secondary to the use of Avitene after enucleation for intraocular retinoblastoma.
  
  
  METHODS
  Eight months after undergoing enucleation for retinoblastoma, a 21-month-old boy underwent a biopsy of an orbital mass.
  
  
  RESULTS
  Histopathologic examination of the orbital biopsy specimen disclosed a proliferative granulomatous foreign body reaction surrounding multiple foci of a coarse fibrillar intercellular substance consistent with Avitene. No retinoblastoma cells were present.
  
  
  CONCLUSIONS
  A foreign body reaction should be included in the differential diagnosis of orbital mass lesions after surgery in which Avitene is used.
authors.affiliation: New York Hospital/Cornell Medical Center, NY, USA.
authors.forename: D H
authors.initials: DH
authors.lastname: Abramson
authors.forename: S
authors.initials: S
authors.lastname: Andracchi
mesh_terms: D003094:Collagen / Q000009:adverse effects*; D003937:Diagnosis, Differential; D015353:Eye Enucleation; D005134:Eye Neoplasms / Q000601:surgery*; D015745:Granuloma, Foreign-Body / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D009916:Orbital Diseases / Q000175:diagnosis / Q000209:etiology*; D012175:Retinoblastoma / Q000601:surgery*; D014057:Tomography, X-Ray Computed
chemical_list: D003094:Collagen