title: A dominant mutant receptor from Arabidopsis confers ethylene insensitivity in heterologous plants.
abstract: Ethylene (C2H4) is a gaseous hormone that affects many aspects of plant growth and development. Ethylene perception requires specific receptors and a signal transduction pathway to coordinate downstream responses. The etr1-1 gene of Arabidopsis encodes a mutated receptor that confers dominant ethylene insensitivity. Evidence is presented here that etr1-1 also causes significant delays in fruit ripening, flower sensecence; and flower abscission when expressed in tomato and petunia plants. The ability of etr1-1 to function in heterologous plants suggests that this pathway of hormone recognition and response is highly conserved and can be manipulated.
authors.affiliation: Ceregen Technology, Monsanto Company, Chesterfield, MO 63198, USA.
authors.forename: J Q
authors.initials: JQ
authors.lastname: Wilkinson
authors.forename: M B
authors.initials: MB
authors.lastname: Lanahan
authors.forename: D G
authors.initials: DG
authors.lastname: Clark
authors.forename: A B
authors.initials: AB
authors.lastname: Bleecker
authors.forename: C
authors.initials: C
authors.lastname: Chang
authors.forename: E M
authors.initials: EM
authors.lastname: Meyerowitz
authors.forename: H J
authors.initials: HJ
authors.lastname: Klee
mesh_terms: D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000235:genetics* / Q000502:physiology; D017124:Conserved Sequence; D018076:DNA, Complementary; D005030:Ethylenes / Q000378:metabolism / Q000494:pharmacology*; D005799:Genes, Dominant; D017343:Genes, Plant; D005818:Genetic Engineering / Q000379:methods; D018551:Solanum lycopersicum / Q000187:drug effects / Q000502:physiology; D010940:Plant Proteins / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D030821:Plants, Genetically Modified; D011956:Receptors, Cell Surface / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D015398:Signal Transduction
chemical_list: D018076:DNA, Complementary; D005030:Ethylenes; D010940:Plant Proteins; D011956:Receptors, Cell Surface; C083750:ethylene receptors, plant; C036216:ethylene