title: Preventive mitochondrial replacement.
abstract: Techniques used recently to clone a sheep generate chimeras with the genome of the donor cell and mainly the mitochondria of the acceptor egg. The use of the same techniques should allow a mother carrying a mitochondrial defect to bear a normal child with normal mitochondria.
authors.affiliation: The Salk Institute for Biological Studies, PO Box 85800, San Diego, CA 92186 5800, USA. orgel@sc2.salk.edu
authors.forename: L E
authors.initials: LE
authors.lastname: Orgel
mesh_terms: D000818:Animals; D003001:Cloning, Molecular; D004992:Ethics, Medical; D005818:Genetic Engineering; D006801:Humans; D008928:Mitochondria / Q000502:physiology*