Advances in treatment: immunoglobulin A nephropathy.
In this article, we consider a number of treatment options for patients with IgA nephropathy. Major emphasis will be placed on the use of corticosteroids and fish oil capsules because these have shown the most promise in recent publications. We also consider the specific management of two patients with severe manifestations of this disease and describe their responses. Finally, we consider future avenues of research into the treatment of IgA nephropathy. This includes a brief description of a three-arm multicenter, placebo-controlled study evaluating alternate-day prednisone and highly purified fish oil concentrate (Omacor) in children and young adults with moderately severe forms of IgA nephropathy.
Hogg
R J
RJ
Department of Pediatrics, Medical City Dallas Hospital, TX 75230-2518, USA.
Waldo
B
B
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D002648:Child; D018849:Controlled Clinical Trials as Topic / Q000639:trends; D005260:Female; D005395:Fish Oils / Q000627:therapeutic use*; D005544:Forecasting; D005922:Glomerulonephritis, IGA / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D008297:Male; D011379:Prognosis
D000305:Adrenal Cortex Hormones; D005395:Fish Oils