[Spontaneous liver rupture after thrombolytic therapy with streptokinase].
Two months after an osteosynthesis of a Maisonneuve-fracture a 45-year-old patient developed a thrombosis of the deep veins on the side of the fracture. Subsequent to two days of lysis with Streptokinase a rupture of the liver occurred and was treated by hemihepatectomy. A traumatic event or a tumor could be excluded as reason for the rupture. Therefore a rupture of the liver due to the application of Streptokinase has to be assumed.
Hinterthaner
M
M
Klinik und Poliklinik für Chirurgie, Rheinischen Friedrich-Wilhelms-Universität, Born.
Kaminski
M
M
Hirner
A
A
Fischer
H P
HP
D056486:Chemical and Drug Induced Liver Injury; D017809:Fatal Outcome; D005260:Female; D018409:Foot Injuries / Q000601:surgery*; D005593:Fracture Fixation, Internal; D006801:Humans; D008099:Liver / Q000473:pathology; D008107:Liver Diseases / Q000473:pathology; D008875:Middle Aged; D011183:Postoperative Complications / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D012422:Rupture, Spontaneous; D013300:Streptokinase / Q000008:administration & dosage / Q000009:adverse effects*; D015912:Thrombolytic Therapy; D013924:Thrombophlebitis / Q000188:drug therapy*
D013300:Streptokinase