title: [Effectiveness of cefpirome in the treatment of complicated infections of the upper and lower urinary tracts].
abstract: Two hundred and two isolates of gram-positive and gram-negative pathogens of urinary tract infection were tested for their susceptibility to cefpirome. In 64 to 97 per cent of the cases the susceptibility was high and exceeded that of other cephalosporins used in the treatment of urological patients. Cefpirome was used in the treatment of 26 patients with signs of urinary tract infection: 19 patients with pyelonephritis and 7 patients with prostatitis. The antibiotic was administered intravenously in a dose of 1 g twice a day for the treatment course of 5-7-10 days. The clinical and bacteriological efficacies amounted to 92 and 87 per cent respectively. The drug tolerance was good. The results demonstrated that cefpirome was useful in the empirical therapy of urinary tract infection.
authors.forename: I I
authors.initials: II
authors.lastname: Derevianko
authors.forename: G A
authors.initials: GA
authors.lastname: Kotliarova
authors.forename: E M
authors.initials: EM
authors.lastname: Kondrat'eva
authors.forename: L A
authors.initials: LA
authors.lastname: Khodyreva
authors.forename: V N
authors.initials: VN
authors.lastname: Siniukhin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D002439:Cefotaxime / Q000627:therapeutic use; D002442:Ceftazidime / Q000627:therapeutic use; D002511:Cephalosporins / Q000009:adverse effects / Q000627:therapeutic use*; D002512:Cephalothin / Q000627:therapeutic use; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000187:drug effects / Q000302:isolation & purification; D006801:Humans; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D016896:Treatment Outcome; D014552:Urinary Tract Infections / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D000097572:Cefpirome
chemical_list: D002439:Cefotaxime; D002442:Ceftazidime; D002511:Cephalosporins; D002512:Cephalothin; D000097572:Cefpirome