title: A case of intrauterine medical treatment for cystic hygroma.
abstract: We report the first case of an intrauterine treatment for cystic hygroma. Guided by ultrasonography, we first removed intracystic fluid from two cysts and then injected OK-432 into each fetal cyst at 21 and 28 weeks of gestation. No re-enlargement of the cysts was subsequently observed. At 38 weeks of gestation, a male infant was delivered transvaginally. Only a slight skin fold was observed in the nuchal area of the neonate, indicating the effectiveness of OK-432 for the intrauterine treatment of cystic hygroma.
authors.affiliation: Department of Obstetrics and Gynecology, Hokkaido University School of Medicine, Sapporo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Watari
authors.forename: H
authors.initials: H
authors.lastname: Yamada
authors.forename: T
authors.initials: T
authors.lastname: Fujino
authors.forename: K
authors.initials: K
authors.lastname: Okuyama
authors.forename: T
authors.initials: T
authors.lastname: Sagawa
authors.forename: S
authors.initials: S
authors.lastname: Makinoda
authors.forename: S
authors.initials: S
authors.lastname: Fujimoto
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D018191:Lymphangioma, Cystic / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008297:Male; D010844:Picibanil / Q000008:administration & dosage / Q000627:therapeutic use*; D011247:Pregnancy; D016216:Ultrasonography, Prenatal
chemical_list: D000970:Antineoplastic Agents; D010844:Picibanil