[Neuroendocrine tumor of the bladder apropos of a case. Review of the literature].
Neuroendocrine bladder tumours are exceptional, and the positive diagnosis is only established when they are already large and advanced. We report an original case in view of its small dimensions. We discuss the differential diagnosis (mainly bladder metastases from lung cancer) and pathological specificities, particularly the value of epithelial immunolabelling allowing exclusion of lymphoma. Because of the similarities with bronchial neuroendocrine tumours, the potential value of serum NSE assay should be emphasized. Combined surgery-cisplatin-based adjuvant chemotherapy is recommended.
Avances
C
C
Service d'Urologie Andrologie, Hôpital Gaston Doumergue, Nîmes, France.
Mottet
N
N
Chapuis
H
H
Dagues
F
F
Ben Naoum
K
K
Louis
J F
JF
Costa
P
P
Marty-Double
C
C
Navratil
H
H
D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002272:Carcinoembryonic Antigen / Q000032:analysis; D018278:Carcinoma, Neuroendocrine / Q000473:pathology* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007633:Keratins / Q000032:analysis; D008175:Lung Neoplasms / Q000473:pathology; D008223:Lymphoma / Q000473:pathology; D018396:Mucin-1 / Q000032:analysis; D009367:Neoplasm Staging; D010751:Phosphopyruvate Hydratase / Q000097:blood; D016708:Synaptophysin / Q000032:analysis; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000556:secondary / Q000601:surgery
D000970:Antineoplastic Agents; D002272:Carcinoembryonic Antigen; D018396:Mucin-1; D016708:Synaptophysin; D007633:Keratins; D010751:Phosphopyruvate Hydratase; D002945:Cisplatin