title: Results of two levels of adjunctive treatment used with the nicotine patch.
abstract: The authors compared 9-, 16-, 26-, and 52-week outcomes for two randomly assigned groups of nicotine-dependent subjects: 1) nicotine patch plus four smoking cessation sessions with a nurse-practitioner giving advice and instruction (n = 36; moderate-intensity condition, MI); or 2) the foregoing treatments plus 16 weekly individual cognitive/ behavioral relapse-prevention therapy sessions (n = 33; high-intensity condition, HI). Patch completion rates were 69.7% in the HI group and 55.6% in the MI group (NS). Self-reported abstinence rates at the four follow-up points were comparable for the two treatment groups; HI: 39%, 36%, 36%, and 36%; MI: 44%, 28%, 25%, and 28%, respectively. There was some indication that MI patients with high nicotine dependence had lower abstinence rates than highly dependent HI patients.
authors.affiliation: University of Pennsylvania School of Medicine, Philadelphia 19104, USA.
authors.forename: P
authors.initials: P
authors.lastname: Lifrak
authors.forename: P
authors.initials: P
authors.lastname: Gariti
authors.forename: A I
authors.initials: AI
authors.lastname: Alterman
authors.forename: J
authors.initials: J
authors.lastname: McKay
authors.forename: J
authors.initials: J
authors.lastname: Volpicelli
authors.forename: T
authors.initials: T
authors.lastname: Sparkman
authors.forename: C
authors.initials: C
authors.lastname: O'Brien
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D000368:Aged; D015928:Cognitive Behavioral Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009538:Nicotine / Q000008:administration & dosage*; D018722:Nicotinic Agonists / Q000008:administration & dosage*; D010353:Patient Education as Topic; D011446:Prospective Studies; D012008:Recurrence; D016540:Smoking Cessation / Q000379:methods*; D014029:Tobacco Use Disorder / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D018722:Nicotinic Agonists; D009538:Nicotine