Unusual atrial pro-arrhythmic effect of flecainide: a contemporary review.
The authors report the case of a patient with drug-resistant atrial fibrillation, who developed, for more than 2 hours, a well-tolerated attack of palpitations, after taking 500 mg of flecainide acetate. The Holter monitoring demonstrated atrial flutter with 1:1 AV conduction and a ventricular rate at 220 bpm. This atrial pro-arrhythmic effect is rare and the mechanism is discussed.
De Meester
A
A
Division of Cardiology, Jolimont Hospital, Haine-Saint-Paul, Belgium.
Machiels
J P
JP
Rousseau
L
L
Luwaert
R
R
Chaudron
J M
JM
D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D001282:Atrial Flutter / Q000139:chemically induced*; D015716:Electrocardiography, Ambulatory; D005260:Female; D005424:Flecainide / Q000009:adverse effects*; D006801:Humans
D000889:Anti-Arrhythmia Agents; D005424:Flecainide