title: RNA movement between the nucleus and the cytoplasm.
abstract: The past year has seen significant advances in our understanding of the mechanism of RNA movement between the nucleus and the cytoplasm. The emerging view is that proteins bind to and escort RNAs to their proper subcellular location. The discovery of peptide signals that target nuclear export and the identification of novel protein mediators of RNA export are examples of significant recent discoveries.
authors.affiliation: Division of Cellular and Molecular Biology Dana-Farber Cancer Institute Department of Biological Chemistry and Molecular Pharmacology Harvard Medical School 44 Binney Street, Boston, Massachusetts, 02115, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Lee
authors.forename: P A
authors.initials: PA
authors.lastname: Silver
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism; D006160:Guanosine Triphosphate / Q000378:metabolism; D006801:Humans; D006868:Hydrolysis; D008969:Molecular Sequence Data; D039502:Nuclear Cap-Binding Protein Complex; D009685:Nuclear Envelope; D010750:Phosphoproteins / Q000378:metabolism; D012313:RNA / Q000378:metabolism*; D029701:Saccharomyces cerevisiae Proteins; D014764:Viral Proteins
chemical_list: C100383:CBC2 protein, S cerevisiae; D039502:Nuclear Cap-Binding Protein Complex; D010750:Phosphoproteins; D029701:Saccharomyces cerevisiae Proteins; D014764:Viral Proteins; D012313:RNA; D006160:Guanosine Triphosphate