The Y specific growth gene(s): how does it promote stature?
Although the presence of a Y specific growth gene(s) (Y growth gene(s) on Yq has widely been accepted, it remains unknown how this gene promotes stature. In this report, we discuss the growth pattern in normal boys and girls and in patients with growth disorders informative for the Y growth gene(s). The results suggest that the Y growth gene(s) augments statural growth by controlling the sex steroid independent childhood growth pattern.
Ogata
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Department of Paediatrics, Keio University School of Medicine, Tokyo, Japan.
Matsuo
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D000293:Adolescent; D001827:Body Height / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D005260:Female; D017353:Gene Deletion; D006130:Growth Disorders / Q000235:genetics; D006801:Humans; D007223:Infant; D008297:Male; D009154:Mutation; D012729:Sex Chromosome Aberrations / Q000235:genetics*; D014998:Y Chromosome