Coexistence of a graft with the preserved native liver in auxiliary partial orthotopic liver transplantation from a living donor for ornithine transcarbamylase deficiency.
BACKGROUND
Auxiliary partial orthotopic liver transplantation (APOLT) has recently been performed in patients with noncirrhotic metabolic liver diseases. However, long-term outcomes for the preserved native liver and the transplanted liver graft have not been clearly established yet.


METHODS
The recipient was a 36-month-old girl with ornithine transcarbamylase deficiency. She underwent APOLT, using her father's left lateral segment.


RESULTS
Liver function was normalized soon after APOLT and the patient was able to ingest a normal diet without medication. Coexistence of the well-functioning native liver and graft was demonstrated in a computed tomography scan, Doppler ultrasonography, scintigraphy, and histological examination, during a relatively long-term follow-up period.


CONCLUSIONS
APOLT seems to be most useful for the treatment of noncirrhotic metabolic liver diseases.
Uemoto
S
S
Department of Transplantation and Immunology, Kyoto University Graduate School of Medicine, Kyoto University Hospital, Shogoin, Sakyo-ku, Japan.
Yabe
S
S
Inomata
Y
Y
Nishizawa
H
H
Asonuma
K
K
Egawa
H
H
Kiuchi
T
T
Okajima
H
H
Yamaoka
Y
Y
Yamabe
H
H
Inui
A
A
Fujisawa
T
T
Tanaka
K
K
D001706:Biopsy; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology / Q000502:physiology*; D016031:Liver Transplantation / Q000000981:diagnostic imaging / Q000379:methods / Q000473:pathology / Q000502:physiology*; D020163:Ornithine Carbamoyltransferase Deficiency Disease; D011859:Radiography