title: Early delineation of cerebral glioma using amino acid positron tracers.
abstract: A 56-yr-old housewife with cerebral astrocytoma was reported with positron emission tomography findigns using 11C-methyl-L-methionine (11C-Met) and 18F-fluorophenylalanine (18F-Phe) tracers. 11C-Met and 18F-Phe accumulated intensely in tumor lesions, although CT scans showed only a foggy low-density area. Five years and one month after, an enhancing mass appeared on CT scans. Thus, amino acid tracers may play a important role in the early diagnosis of gliomas.
authors.affiliation: Neurosurgical Service, Akita University Hospital, Japan. mineura@med.akita-u.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Mineura
authors.forename: T
authors.initials: T
authors.lastname: Sasajima
authors.forename: M
authors.initials: M
authors.lastname: Kowada
authors.forename: T
authors.initials: T
authors.lastname: Ogawa
authors.forename: J
authors.initials: J
authors.lastname: Hatazawa
authors.forename: K
authors.initials: K
authors.lastname: Uemura
mesh_terms: D001254:Astrocytoma / Q000000981:diagnostic imaging*; D001932:Brain Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008715:Methionine / Q000031:analogs & derivatives*; D008875:Middle Aged; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed; D010135:p-Fluorophenylalanine
chemical_list: D010135:p-Fluorophenylalanine; D008715:Methionine; C038344:methionine methyl ester