Funduscopy versus photographic assessment of cytomegalovirus retinitis progression: a clinician's perspective.
OBJECTIVE
Funduscopy was compared with retinal photographs in the documentation of progression of cytomegalovirus (CMV) retinitis.


METHODS
Clinical centres provided oral ganciclovir maintenance therapy for AIDS patients with CMV retinitis inaccurately involved in randomized trials of oral versus intravenous ganciclovir for maintenance therapy of patients with newly diagnosed or previously treated CMV retinitis, in North America, Europe and Australia.


METHODS
Serial retinal photographs and funduscopy examinations were conducted at each patient visit in order to detect progression of CMV retinitis during the course of oral ganciclovir maintenance therapy.


CONCLUSIONS
Retinal photography is the most accurate for central lesions, funduscopy is preferable for diffuse and peripheral lesions, and in the day-to-day management of patients, the combined approach provides the most accurate information.
Migdal
C
C
Western Eye Hospital, London, UK.
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy / Q000503:physiopathology*; D000284:Administration, Oral; D000998:Antiviral Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D017726:Cytomegalovirus Retinitis / Q000150:complications / Q000188:drug therapy / Q000503:physiopathology*; D005451:Fluorescein Angiography; D015774:Ganciclovir / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007262:Infusions, Intravenous; D009887:Ophthalmoscopy
D000998:Antiviral Agents; D015774:Ganciclovir