title: [High-resolution computerized tomography in diffuse forms of bronchiolo-alveolar carcinoma].
abstract: Bronchioloalveolar carcinoma (BAC) is a relatively uncommon tumor of the lung accounting for 1 to 9% of all pulmonary neoplasms. Its radiologic appearance is characterized by solitary nodular opacity or diffuse air-space consolidation. The aim of this work is to report the different patterns of this neoplasm, particularly in the diffuse form, and to demonstrate the sensitivity and specificity of HRCT in its early identification. We examined 11 patients affected with multifocal bronchioloalveolar carcinoma to identify HRCT signs which could lead to improved diagnostic criteria. These signs are represented by ground-glass opacity (8/11) and alveolar consolidation (6/11), with a plurilobular, segmentary or lobar distribution. The lesions were bilateral in 8/11 cases and abnormal mediastinal lymph nodes were found in 5/11 cases. Air bronchogram was seen in all cases of ground-glass opacity and in 5/11 cases of air-space consolidation. In conclusion, in our experience, HRCT is a useful tool in the study of BAC, which has a long and slow evolution and is underestimated at chest radiograph in its early stage. Moreover, HRCT can help distinguish this condition from other lung diseases characterized by diffuse air-space consolidations, whose clinical history is useless to make an unquestionable diagnosis.
authors.affiliation: Servizio di Radiologia e Diagnostica per Immagini, Ospedale Luigi Sacco, Milano.
authors.forename: L
authors.initials: L
authors.lastname: Dellafiore
authors.forename: B
authors.initials: B
authors.lastname: Tagliaferri
authors.forename: R
authors.initials: R
authors.lastname: Bianco
authors.forename: S
authors.initials: S
authors.lastname: Soldi
authors.forename: A
authors.initials: A
authors.lastname: Tentori
authors.forename: G P
authors.initials: GP
authors.lastname: Cornalba
mesh_terms: D002282:Adenocarcinoma, Bronchiolo-Alveolar / Q000000981:diagnostic imaging*; D000368:Aged; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods