title: Effect of bi-level positive airway pressure (BiPAP) nasal ventilation on the postoperative pulmonary restrictive syndrome in obese patients undergoing gastroplasty.
abstract: OBJECTIVE
  Upper abdominal surgery results in a postoperative restrictive pulmonary syndrome. Bi-level positive airway pressure (BiPAP System; Respironics Inc; Murrysville, Pa), which combines pressure support ventilation and positive end-expiratory pressure via a nasal mask, could allow alveolar recruitment during inspiration and prevent expiratory alveolar collapse, and therefore limit the postoperative pulmonary restrictive syndrome. This study investigated the effect of BiPAP on postoperative pulmonary function in obese patients after gastroplasty.
  
  
  METHODS
  Prospective controlled randomized study.
  
  
  METHODS
  GI surgical ward in a university hospital.
  
  
  METHODS
  Thirty-three morbidly obese patients scheduled for gastroplasty were studied.
  
  
  METHODS
  The patients were assigned to one of three techniques of ventilatory support during the first 24 h postoperatively: O2 via a face mask, BiPAP System 8/4, with inspiratory and expiratory positive airway pressure set at 8 and 4 cm H2O, respectively, or BiPAP System 12/4 set at 12 and 4 cm H2O. Pulmonary function (FVC, FEV1, and peak expiratory flow rate [PEFR]) were measured the day before surgery, 24 h after surgery, and on days 2 and 3. Oxygen saturation by pulse oximeter (SpO2) was also recorded during room air breathing.
  
  
  RESULTS
  Three patients were excluded. After surgery, FVC, FEV1, PEFR, and SpO2 significantly decreased in the three groups. On day 1, FVC and FEV1 were significantly improved in the group BiPAP System 12/4, as compared with no BiPAP; SpO2 was also significantly improved. After removal of BiPAP System 12/4, these benefits were maintained, allowing faster recovery of pulmonary function. No significant effects were observed on PEFR. BiPAP System 8/4 had no significant effect on the postoperative pulmonary restrictive syndrome.
  
  
  CONCLUSIONS
  Prophylactic use of BiPAP System 12/4 during the first 24 h postoperatively significantly reduces pulmonary dysfunction after gastroplasty in obese patients and accelerates reestablishment of preoperative pulmonary function.
authors.affiliation: Department of Anesthesia and Intensive Care Medicine, University Hospital of Liège, Belgium.
authors.forename: J L
authors.initials: JL
authors.lastname: Joris
authors.forename: T M
authors.initials: TM
authors.lastname: Sottiaux
authors.forename: J D
authors.initials: JD
authors.lastname: Chiche
authors.forename: C J
authors.initials: CJ
authors.lastname: Desaive
authors.forename: M L
authors.initials: ML
authors.lastname: Lamy
mesh_terms: D000328:Adult; D005260:Female; D015391:Gastroplasty; D006801:Humans; D008297:Male; D008397:Masks; D009767:Obesity, Morbid / Q000601:surgery*; D011175:Positive-Pressure Respiration; D011182:Postoperative Care; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D012120:Respiration Disorders / Q000209:etiology / Q000517:prevention & control*; D015656:Respiratory Mechanics; D013577:Syndrome