title: Biomechanical comparison between BioScrew and titanium alloy interference screws for bone-patellar tendon-bone graft fixation in anterior cruciate ligament reconstruction.
abstract: This investigation compared the maximum load at failure of BioScrew (Linvatec Corp, Largo, FL) and titanium alloy interference screw femoral fixation using a human cadaveric model that approximated the anatomical orientation and physiological strain rate of in vivo bone-patellar tendon-bone (BPTB) graft loading following anterior cruciate ligament reconstruction. Eighteen fresh-frozen human BPTB allografts (10-mm wide, 10-mm thick, 25-mm long bone plugs) with either BioScrew or titanium alloy (Ti 6A14V) screw (7 x 25 mm) fixation were compared for maximum load at failure at a strain rate of 20 mm/minute. Nine cadaver femurs with bone mineral densities of 0.88 +/- 0.18 g/cm2 (anterior/posterior) and 1.3 +/- 0.24 g/cm2 (lateral) received the allografts. No statistical differences were observed in maximum load at failure (P = .95) or failure mode (P = .11) between specimens fixed with either screw type. When biomechanically tested with anatomic orientation and at functionally relevant strain rates, the BioScrew provided maximum load at failure equal to a titanium alloy screw.
authors.affiliation: Division of Orthopaedic Surgery, University of Kentucky, School of Medicine, Lexington, USA.
authors.forename: D N
authors.initials: DN
authors.lastname: Caborn
authors.forename: W P
authors.initials: WP
authors.lastname: Urban
authors.forename: D L
authors.initials: DL
authors.lastname: Johnson
authors.forename: J
authors.initials: J
authors.lastname: Nyland
authors.forename: D
authors.initials: D
authors.lastname: Pienkowski
mesh_terms: D000042:Absorption; D016118:Anterior Cruciate Ligament / Q000601:surgery*; D001696:Biomechanical Phenomena; D001863:Bone Screws; D016025:Bone Transplantation; D006801:Humans; D066298:In Vitro Techniques; D017847:Patellar Ligament / Q000637:transplantation*; D011091:Polyesters; D014025:Titanium
chemical_list: D011091:Polyesters; C033616:poly(lactide); D014025:Titanium