[Study of pulmonary epithelial permeability in healthy non-smokers].
OBJECTIVE
To measure the pulmonary epithelial permeability in non-smoker healthy adult individuals, establishing the normal pattern in our milieu and to correlate the findings according to age, sex, weight, height and body surface area.


METHODS
24 healthy non-smokers using the rate of pulmonary depuration of 99mTc-DTPA as an index of pulmonary epithelial permeability were studied. The given information was correlated to sex, age, weight, height and body surface area.


RESULTS
The averages found for the pulmonary depuration rate for 99mTc-DTPA were 0.82% +/- 0.19 min-1 for the left lung and of 0.88% +/- 0.23 min-1 for the right lung. No statistically significant relation with sex, age, weight, height and body surface area was found.


CONCLUSIONS
The given data are within the interindividual variation described in the literature, in the studied age period, and must be considered as standard values among us.
Dalcin
P T
PT
Serviço de Medicina Nuclear do Hospital de Clínicas de Porto Alegre, RS.
da Rocha
P M
PM
Marroni
B J
BJ
Menna-Barreto
S S
SS
D000328:Adult; D000336:Aerosols; D001827:Body Height; D001830:Body Surface Area; D001835:Body Weight; D004848:Epithelium / Q000378:metabolism; D005260:Female; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000378:metabolism*; D008297:Male; D010539:Permeability; D011877:Radionuclide Imaging; D016284:Technetium Tc 99m Pentetate
D000336:Aerosols; D016284:Technetium Tc 99m Pentetate