title: Radiofrequency thermal ablation of the prostate: the TUNA technique.
abstract: Radiofrequency (RF) needle ablation has been developed for use in treating the symptoms caused by benign prostatic hyperplasia. The transurethral needle ablation (TUNA) device permits accurate needle placement in the prostate and the RF generator has been designed to create reproducible lesions in prostate tissue. The procedure may be done on an outpatient basis using topical anesthesia only. Fifteen patients were studied prospectively as part of a Canadian multicenter trial. Significant improvements in peak flow (7.4-8.9 ml/s), A.U.A. Symptom Score (21-16) and Quality of Life score (4.6-3.1) have been documented in early follow-up, mirroring the improvements found in other series. The technique was well tolerated and resulted in a 20% retention rate. TUNA is a minimally invasive technique that has been shown to create lesions in the prostate and is suitable for outpatient application. Early results show a clinical effect. The ultimate indications and role for this technique will be established by randomized controlled study.
authors.affiliation: Department of Urology, Queen's University, Kingston, Ontario, Canada.
authors.forename: J P
authors.initials: JP
authors.lastname: Heaton
mesh_terms: D000556:Ambulatory Surgical Procedures; D000772:Anesthesia, Local; D004564:Electrocoagulation / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D004867:Equipment Design; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D009339:Needles; D018579:Patient Selection; D011446:Prospective Studies; D011468:Prostatectomy / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D011470:Prostatic Hyperplasia / Q000601:surgery; D011788:Quality of Life; D011846:Radio Waves; D016032:Randomized Controlled Trials as Topic; D015203:Reproducibility of Results; D016896:Treatment Outcome; D016055:Urinary Retention / Q000209:etiology; D014554:Urination