title: Foodborne outbreaks of human toxoplasmosis.
abstract: Two outbreaks of acute toxoplasmosis involving 8 adult patients in Korea were linked to eating uncooked pork. In the first outbreak, 3 patients developed unilateral chorioretinitis within 3 months of eating a meal consisting of raw spleen and liver of a wild pig. In the second outbreak, 5 of 11 soldiers who ate a meal consisting of raw liver of a domestic pig developed lymphadenopathy. All 8 patients had high levels of IgG Toxoplasma gondii antibodies (> or = 1:1024) in the Sabin-Feldman dye test, modified agglutination test incorporating mercaptoethanol, and latex agglutination test. T. gondii IgM antibodies persisted in these patients for several months. Most patients had a favorable response to anti-T. gondii chemotherapy with pyrimethamine and sulfanomides.
authors.affiliation: Department of Parasitology, School of Medicine, Catholic University of Korea, Seoul.
authors.forename: W Y
authors.initials: WY
authors.lastname: Choi
authors.forename: H W
authors.initials: HW
authors.lastname: Nam
authors.forename: N H
authors.initials: NH
authors.lastname: Kwak
authors.forename: W
authors.initials: W
authors.lastname: Huh
authors.forename: Y R
authors.initials: YR
authors.lastname: Kim
authors.forename: M W
authors.initials: MW
authors.lastname: Kang
authors.forename: S Y
authors.initials: SY
authors.lastname: Cho
authors.forename: J P
authors.initials: JP
authors.lastname: Dubey
mesh_terms: D000328:Adult; D000372:Agglutination Tests; D000818:Animals; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000913:Antibodies, Protozoan / Q000097:blood; D004196:Disease Outbreaks; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007723:Korea / Q000453:epidemiology; D008297:Male; D008460:Meat / Q000469:parasitology*; D008875:Middle Aged; D011739:Pyrimethamine / Q000627:therapeutic use; D013449:Sulfonamides / Q000627:therapeutic use; D013552:Swine; D014123:Toxoplasmosis / Q000188:drug therapy / Q000453:epidemiology* / Q000276:immunology / Q000635:transmission; D014126:Toxoplasmosis, Ocular / Q000188:drug therapy / Q000635:transmission
chemical_list: D000890:Anti-Infective Agents; D000913:Antibodies, Protozoan; D007074:Immunoglobulin G; D013449:Sulfonamides; D011739:Pyrimethamine