title: Preliminary clinical experience with the first dual chamber pacemaker defibrillator.
abstract: The lack of specificity of VT detection is a significant shortcoming of current ICDs. In a French multicenter study, 18 patients underwent implantation of the Defender 9001 (ELA Medical), an ICD utilizing dual chamber pacing and arrhythmia detection. Over a mean follow-up period of 7.1 +/- 4.5 months, 176 tachycardia episodes recorded in the device memory were analyzed, and physician diagnosis was compared with that by the device. All 122 VT/VF episodes were correctly diagnosed, as were 51 of 53 supraventricular tachyarrhythmias. Two episodes of AF with rapid regular ventricular rates were treated as VT, and a third episode, treated as VT, could not be diagnosed with certainty. A dual chamber pacemaker defibrillator offers improved diagnostic specificity without loss of sensitivity, in addition to the hemodynamic benefit of dual chamber pacing.
authors.affiliation: Hôpital Broussais, Paris, France.
authors.forename: T
authors.initials: T
authors.lastname: Lavergne
authors.forename: J C
authors.initials: JC
authors.lastname: Daubert
authors.forename: M
authors.initials: M
authors.lastname: Chauvin
authors.forename: E
authors.initials: E
authors.lastname: Dolla
authors.forename: S
authors.initials: S
authors.lastname: Kacet
authors.forename: A
authors.initials: A
authors.lastname: Leenhardt
authors.forename: P
authors.initials: P
authors.lastname: Mabo
authors.forename: P
authors.initials: P
authors.lastname: Ritter
authors.forename: N
authors.initials: N
authors.lastname: Sadoul
authors.forename: N
authors.initials: N
authors.lastname: Saoudi
authors.forename: C
authors.initials: C
authors.lastname: Henry
authors.forename: R
authors.initials: R
authors.lastname: Nitzsche
authors.forename: A
authors.initials: A
authors.lastname: Ripart
authors.forename: F
authors.initials: F
authors.lastname: Murgatroyd
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000465:Algorithms; D001145:Arrhythmias, Cardiac / Q000175:diagnosis / Q000628:therapy; D001281:Atrial Fibrillation / Q000175:diagnosis / Q000628:therapy; D002304:Cardiac Pacing, Artificial; D017147:Defibrillators, Implantable; D004867:Equipment Design; D005080:Exercise Test; D005260:Female; D005500:Follow-Up Studies; D005602:France; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial; D010820:Physicians; D012680:Sensitivity and Specificity; D013610:Tachycardia / Q000175:diagnosis; D013617:Tachycardia, Supraventricular / Q000175:diagnosis / Q000628:therapy; D017180:Tachycardia, Ventricular / Q000175:diagnosis; D014693:Ventricular Fibrillation / Q000175:diagnosis / Q000628:therapy