title: Evaluation of an aqueous injection of ketoprofen.
abstract: The increase in aqueous solubility of ketoprofen using hydrotropes and cosolvents in formulation, as well as stability studies of its aqueous injections have been reported earlier. These formulations were further evaluated in vitro (physical evaluation, haemolytic activity) and in vivo (pharmacokinetic studies). Some of the formulations have shown promising results.
authors.affiliation: Department of Pharmaceutical Sciences, Dr. H. S. Gour University, Sagar (M.P.) India.
authors.forename: A K
authors.initials: AK
authors.lastname: Singhai
authors.forename: S
authors.initials: S
authors.lastname: Jain
authors.forename: N K
authors.initials: NK
authors.lastname: Jain
mesh_terms: D000284:Administration, Oral; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage* / Q000493:pharmacokinetics / Q000494:pharmacology; D000818:Animals; D019540:Area Under Curve; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004912:Erythrocytes / Q000187:drug effects; D005079:Excipients; D006461:Hemolysis / Q000187:drug effects; D066298:In Vitro Techniques; D007275:Injections, Intravenous; D007660:Ketoprofen / Q000008:administration & dosage* / Q000493:pharmacokinetics / Q000494:pharmacology; D011817:Rabbits
chemical_list: D018712:Analgesics, Non-Narcotic; D005079:Excipients; D007660:Ketoprofen