Some observations on the cardiotoxic and drug interaction profiles of second generation antihistamines as measured in the guinea pig.
Roberts
D J
DJ
Pharmacological Department, Research Institute Laboratorios, Barcelona, Spain.
Llenas
J
J
D000818:Animals; D000935:Antifungal Agents / Q000008:administration & dosage / Q000633:toxicity; D002090:Butyrophenones / Q000008:administration & dosage / Q000633:toxicity; D004195:Disease Models, Animal; D004347:Drug Interactions; D004562:Electrocardiography / Q000187:drug effects; D006168:Guinea Pigs; D006634:Histamine H1 Antagonists / Q000633:toxicity*; D007275:Injections, Intravenous; D007654:Ketoconazole / Q000008:administration & dosage / Q000633:toxicity; D010880:Piperidines / Q000008:administration & dosage / Q000633:toxicity; D016593:Terfenadine / Q000008:administration & dosage / Q000633:toxicity; D016171:Torsades de Pointes / Q000139:chemically induced*
D000935:Antifungal Agents; D002090:Butyrophenones; D006634:Histamine H1 Antagonists; D010880:Piperidines; D016593:Terfenadine; D007654:Ketoconazole; C058249:ebastine