title: Gastric ulcers in horses: a comparison of endoscopic findings in horses with and without clinical signs.
abstract: Gastroendoscopic examinations were performed on 187 horses, ranging from one to 24 years. Eighty-seven horses had clinical problems including chronic, recurrent colic for seven or more days (25), one or more episodes of colic within the previous seven days (13), or acute colic (10), diminished appetite (53), poor bodily condition (40), and/or chronic diarrhoea (9). One hundred horses that had no signs of gastrointestinal problems were examined as part of a gastroendoscopic survey. Lesions observed in the squamous fundus, squamous mucosa adjacent to the margo plicatus along the greater curvature, glandular fundus, and the squamous mucosa along the lesser curvature were scored on a scale of 0-4, with 0 representing no lesions and 4 representing the most severe lesions. The mean endoscopic scores for the squamous fundus, margo plicatus and lesser curvature were significantly greater (P < 0.001) in horses with clinical signs than those without signs. This was because of the greater number of horses with lesions in the symptomatic group (80/87) compared to those without signs (52/100), and the greater severity of lesions in the horses with clinical signs. Of the horses, 74 were in race training. There was a significantly (P < 0.01) greater prevalence and severity of lesions at all sites except the glandular fundus in horses in training compared to those not in training, and in the horses in training with clinical signs (n = 37) compared to those in training without clinical signs (n = 37).
authors.affiliation: Marion duPont Scott Equine Medical Center, Virginia-Maryland Regional College of Veterinary Medicine, Leesburg 22075, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Murray
authors.forename: C
authors.initials: C
authors.lastname: Grodinsky
authors.forename: C W
authors.initials: CW
authors.lastname: Anderson
authors.forename: P F
authors.initials: PF
authors.lastname: Radue
authors.forename: G R
authors.initials: GR
authors.lastname: Schmidt
mesh_terms: D000818:Animals; D003085:Colic / Q000503:physiopathology / Q000662:veterinary; D003967:Diarrhea / Q000503:physiopathology / Q000662:veterinary; D016099:Endoscopy, Gastrointestinal / Q000379:methods / Q000662:veterinary*; D005753:Gastric Mucosa / Q000473:pathology; D006734:Horse Diseases / Q000453:epidemiology / Q000473:pathology* / Q000503:physiopathology; D006736:Horses; D010146:Pain / Q000503:physiopathology / Q000662:veterinary; D015995:Prevalence; D012720:Severity of Illness Index; D013270:Stomach / Q000473:pathology; D013276:Stomach Ulcer / Q000473:pathology / Q000503:physiopathology / Q000662:veterinary*; D015431:Weight Loss / Q000502:physiology