Postsynaptic calcium and calcium-dependent processes in synaptic plasticity in the developing visual cortex.
In this paper we describe some of the results obtained from recent experiments on mechanisms underlying long-term potentiation (LTP) and long-term depression (LTD) in the visual cortex of young rats. In particular, we focus on experiments which tested the hypotheses that the induction of LTP in the visual cortex is of Hebbian type and that an input-associated Ca2+ rise at postsynaptic sites and subsequent activation of protein kinases or protein phosphatases may play roles in the induction of LTP or LTD in the developing visual cortex.
Tsumoto
T
T
Department of Neurophysiology, Osaka University Medical School, Suita City, Japan.
Yasuda
H
H
Fukuda
M
M
Akaneya
Y
Y
D000818:Animals; D002118:Calcium / Q000378:metabolism / Q000502:physiology*; D005470:Fluorometry; D017774:Long-Term Potentiation / Q000502:physiology; D009473:Neuronal Plasticity / Q000502:physiology*; D009474:Neurons / Q000378:metabolism; D010766:Phosphorylation; D013569:Synapses / Q000502:physiology*; D014793:Visual Cortex / Q000254:growth & development / Q000502:physiology*
D002118:Calcium