[A pathological study of cytomegalovirus infections in autopsied cases with adult T-cell leukemia].
In this study, cytomegalovirus (CMV) infection was found in eleven of 21 autopsied cases (52.4%) with adult T-cell leukemia (ATL). Seven cases (63.6%) revealed disseminated infection in more than three organs. The lungs were involved in all eleven cases (100%), adrenal glands in eight cases (72.7%), esophagus in four cases (36.4%), and stomach, small intestine and urinary bladder in three cases (27.3%). Histopathological findings suggested that lung involvement was the cause of death in five of the 11 cases, the small intestine were involved in two of the 3 cases, and the adrenal glands were involved in one of the 8 cases. In summary, CMV infection was found to be the main cause of death in five (45.5%) of the 11 ATL patients.
Nagaoka
H
H
Second Department of Internal Medicine, Oita Medical University.
Tokimatsu
I
I
Yamasaki
T
T
Nagai
H
H
Otsuka
E
E
Hashimoto
A
A
Goto
Y
Y
Nasu
M
M
Kikuchi
H
H
Daa
T
T
Akizuki
S
S
D000311:Adrenal Glands / Q000821:virology; D000328:Adult; D000368:Aged; D002423:Cause of Death; D003586:Cytomegalovirus Infections / Q000209:etiology / Q000473:pathology*; D005260:Female; D006801:Humans; D015458:Leukemia, T-Cell / Q000150:complications / Q000473:pathology* / Q000821:virology; D008168:Lung / Q000821:virology; D008297:Male; D008875:Middle Aged; D001743:Urinary Bladder / Q000821:virology