Antiflammins: endogenous nonapeptides with regulatory effect on inflammation.
1. Antiflammins are a new family of peptides that share a common sequence with uteroglobin and lipocortin-1, which retain the anti-inflammatory action of these proteins. 2. However, it is controversial whether or not the antiflammins have any effect on enzymes involved in arachidonic acid mobilization and/or arachidonic acid metabolism. 3. This review summarizes our current knowledge of the properties and activity of antiflammins.
Moreno
J J
JJ
Departamento Ciencias Fisiológicas, Unidad Fisiología, Facultad de Farmacia, Universidad de Barcelona, Spain.
D000818:Animals; D017305:Annexin A1 / Q000737:chemistry* / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry* / Q000494:pharmacology; D016718:Arachidonic Acid / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D009842:Oligopeptides / Q000737:chemistry / Q000378:metabolism* / Q000494:pharmacology; D014598:Uteroglobin / Q000737:chemistry* / Q000494:pharmacology
D017305:Annexin A1; D000894:Anti-Inflammatory Agents, Non-Steroidal; D009842:Oligopeptides; D016718:Arachidonic Acid; D014598:Uteroglobin