title: [Use of immunomodulator polyoxydony in treatment and prevention of septic conditions in surgical patients].
abstract: 52 patients (group 1) with a high risk of postoperative infective and septic complications and 58 surgical patients (group 2) with the developed infective septic complications are analysed. In 32 patients of group 1 and in 37 patients of group 2 immunomodulator Polyoxydony was used. The use of Polyoxydony in patients of both groups contributed to favourable dynamics of immune status, decrease of the rate of complications and postoperative mortality. Polyoxydony is effective medicine in prevention and treatment of postoperative infective and septic complications.
authors.affiliation: Institute of Immunology, Department of Health of Russian Federation.
authors.forename: R M
authors.initials: RM
authors.lastname: Khaitov
authors.forename: T L
authors.initials: TL
authors.lastname: Shchel'tsyna
authors.forename: A A
authors.initials: AA
authors.lastname: Butakov
authors.forename: B V
authors.initials: BV
authors.lastname: Pinegin
authors.forename: N F
authors.initials: NF
authors.lastname: Moskalev
authors.forename: A S
authors.initials: AS
authors.lastname: Ivanova
authors.forename: A V
authors.initials: AV
authors.lastname: Nekrasov
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000293:Adolescent; D000328:Adult; D005500:Follow-Up Studies; D006801:Humans; D007109:Immunity / Q000187:drug effects; D008875:Middle Aged; D009930:Organic Chemicals; D011183:Postoperative Complications / Q000188:drug therapy*; D018805:Sepsis / Q000209:etiology / Q000276:immunology / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D000276:Adjuvants, Immunologic; D009930:Organic Chemicals; C089921:polyoxydonium