title: Liverbiopsy because of Hbs Ag positive hepatitis revealing a non-suspected hepatic schistosomiasis. Implication for future therapy with recombinant alpha interferon?
abstract: A patient with HbsAG positive chronic persistent hepatitis is demonstrated in whom a liver biopsy specimen showed a nonsuspected asymptomatic infection with Schistosoma mansoni. Further investigations showed no signs of liver fibrosis or portal hypertension. Rectal biopsy specimens also showed Schistosoma mansoni. The combination of Schistosomiasis and hepatitis is well known in the literature, the effect of recombinant interferon therapy in these cases, however, is not known. Attention is drawn to this combination.
authors.affiliation: Department of Internal Medicine, Ziekenhuis De Heel Zaandam, The Netherlands.
authors.forename: R J
authors.initials: RJ
authors.lastname: Loffeld
authors.forename: J
authors.initials: J
authors.lastname: Blaauboer
authors.forename: A G
authors.initials: AG
authors.lastname: Blak
mesh_terms: D001706:Biopsy; D002908:Chronic Disease; D006509:Hepatitis B / Q000097:blood / Q000150:complications* / Q000628:therapy; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use; D008099:Liver / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012555:Schistosomiasis mansoni / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy
chemical_list: D006514:Hepatitis B Surface Antigens; D016898:Interferon-alpha