Dipole localization in patients with epilepsy using the realistically shaped head model.
Dipole sources were localized in 3 patients with epilepsy using both the realistically shaped head model and the 3-sphere model. Interictal spikes were recorded from 63 closely spaced scalp electrodes. The scalp, skull, and brain surfaces were digitized from a MRI of each patient's head, and each surface was tessellated by 1600 triangles. Single dipole fits to the EEG were performed using both the realistically shaped head model and the 3-sphere model. The 2 models localized dipoles to positions that differed from one another by 1-3 cm. For dipoles localized to the temporal lobe, the most important difference between models was that the realistically shaped head model localized the dipole lower in the brain than the 3-sphere model. The realistically shaped head model was more in accordance with the ECoG findings than the 3-sphere model.
Roth
B J
BJ
Department of Physics and Astronomy, Vanderbilt University, Nashville, TN 37235, USA. roth@compsci.cas.vanderbilt.edu
Ko
D
D
von Albertini-Carletti
I R
IR
Scaffidi
D
D
Sato
S
S
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000473:pathology*; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000473:pathology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008959:Models, Neurological