[The pharmacodynamics of general anesthetics. The neurological and cardiovascular aspects].
General anaesthesia is defined as a state of pharmacological coma. After a brief review of the central neurotransmission, the active mechanisms of general anaesthesia are analysed, as a pharmacological basis for an adequate understanding of their effects and interactions, with special emphasis on the neurological and cardiovascular aspects.
Vale
F M
FM
Instituto Farmacologia, Faculdade Medicina de Lisboa.
D000759:Adjuvants, Anesthesia / Q000493:pharmacokinetics; D018681:Anesthetics, General / Q000493:pharmacokinetics* / Q000494:pharmacology; D018685:Anesthetics, Inhalation / Q000493:pharmacokinetics; D018686:Anesthetics, Intravenous / Q000493:pharmacokinetics; D000818:Animals; D002319:Cardiovascular System / Q000187:drug effects*; D004347:Drug Interactions; D006801:Humans; D009435:Synaptic Transmission / Q000187:drug effects*
D000759:Adjuvants, Anesthesia; D018681:Anesthetics, General; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous