Structurally related receptors and antagonists compete for secreted Wnt ligands.
Moon
R T
RT
Department of Pharmacology, University of Washington School of Medicine, Seattle 98195, USA.
Brown
J D
JD
Yang-Snyder
J A
JA
Miller
J R
JR
D000818:Animals; D001667:Binding, Competitive / Q000502:physiology; D006023:Glycoproteins; D047908:Intracellular Signaling Peptides and Proteins; D008024:Ligands; D008934:Mitogens / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000378:metabolism; D011506:Proteins / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000378:metabolism; D011518:Proto-Oncogene Proteins / Q000037:antagonists & inhibitors / Q000737:chemistry* / Q000378:metabolism; D051153:Wnt Proteins; D014981:Xenopus; D029961:Zebrafish Proteins; D000099274:Frizzled-Related Proteins
D006023:Glycoproteins; D047908:Intracellular Signaling Peptides and Proteins; D008024:Ligands; D008934:Mitogens; D011506:Proteins; D011518:Proto-Oncogene Proteins; D051153:Wnt Proteins; D029961:Zebrafish Proteins; D000099274:Frizzled-Related Proteins