title: Children with alopecia areata: psychiatric symptomatology and life events.
abstract: OBJECTIVE
  To examine the nature of psychopathology of children with alopecia areata (AA) and to investigate the frequency and quality of life events in the year before AA developed in comparison with a control group.
  
  
  METHODS
  Thirty-three subjects with AA, mean age 10.5 +/- 0.3 years, were compared with 30 controls who visited a pediatrician for a mild condition. In addition, 16 preschool children with AA were compared with 17 preschool children who visited the pediatrician for a mild condition. The following measures were used: Child Psychiatric Interview, Children's Depression Inventory (CDI), Children's Manifest Anxiety Scale (CMAS), Life Events Scale for Children, and Child Behavior Checklist (CBCL).
  
  
  RESULTS
  On the CBCL, children with AA had more psychological problems, in total, than controls, and in particular, they were more anxious or depressed, withdrawn, aggressive, and delinquent. They also had more somatic problems as well as problems in social relations and in attention. Girls with AA seem to have been affected more in dimensions of total problems, anxiety/depression, and internalizing/externalizing syndromes. In terms of anxiety (CMAS), more children with AA than controls seemed to worry and to have difficulties in concentration and physiological symptoms of anxiety. In the Child Psychiatric Interview, all children with AA exhibited symptomatology of anxiety or depression or both, usually of mild or moderate nature. Major depression was not detected through the CDI. Fewer children with AA had positive life events the year before AA than controls in a similar time period.
  
  
  CONCLUSIONS
  Compared with controls, children with AA had more psychiatric symptoms in general and symptoms of anxiety or depression, or both, in particular. There is also evidence that lack of positive life events in the prealopecia period played a role in their lives. Psychiatric assessment, and if necessary treatment, is warranted for all children with this condition.
authors.affiliation: Athens University Medical School, Greece.
authors.forename: M
authors.initials: M
authors.lastname: Liakopoulou
authors.forename: T
authors.initials: T
authors.lastname: Alifieraki
authors.forename: A
authors.initials: A
authors.lastname: Katideniou
authors.forename: T
authors.initials: T
authors.lastname: Kakourou
authors.forename: E
authors.initials: E
authors.lastname: Tselalidou
authors.forename: J
authors.initials: J
authors.lastname: Tsiantis
authors.forename: J
authors.initials: J
authors.lastname: Stratigos
mesh_terms: D000506:Alopecia Areata / Q000150:complications / Q000523:psychology*; D000704:Analysis of Variance; D001007:Anxiety / Q000150:complications*; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D002648:Child; D002652:Child Behavior; D003863:Depression / Q000150:complications*; D005260:Female; D006801:Humans; D008016:Life Change Events; D008297:Male; D012494:Sampling Studies