Biclonal B-cell chronic lymphocytic leukemia with inv(14)(q11q32).
Cytogenetic biclonality is a rare occurrence in chronic lymphocytic leukemia. A 59-year-old man was diagnosed to have B-cell chronic lymphocytic leukemia with typical morphology and immunophenotype (CD5+, CD19+, and CD23+). However, karyotypic analysis of the small lymphocytes showed the presence of two distinct unrelated clones, including one with inv(14).
Wong
K F
KF
Department of Pathology, Queen Elizabeth Hospital, Hong Kong.
So
C C
CC
D000368:Aged; D002869:Chromosome Aberrations / Q000473:pathology*; D002871:Chromosome Banding; D025063:Chromosome Disorders; D007446:Chromosome Inversion; D002882:Chromosomes, Human, Pair 13; D002883:Chromosomes, Human, Pair 14; D002999:Clone Cells; D006801:Humans; D007945:Leukemia, Lymphoid / Q000235:genetics / Q000473:pathology*; D008297:Male