Follicular lymphomatoid papulosis.
A case of follicular lymphomatoid papulosis (LyP) is reported. The patient was a 60-year-old Japanese woman. Clinically, cutaneous eruptions were reddish, centrally depressed, dome-shaped papules on the extensor aspect of the forearm. Histologically, they exhibited features that fulfilled the disease criteria described by Pierard, et al., i.e., (Am J Dermatopathol 1980;2:173-80), mixed cellular infiltrates including atypical Reed-Sternberg cell-like type-A cells and mycosis cell-like type-B cells surrounding hyperplastic follicular epithelia. The patient also showed many typical nonfollicular LyP papules, i.e., rhythmically recurrent papules which underwent spontaneous involution within a few weeks, over a 10-year period. The coincidental occurrence of a rare variant of follicular LyP and typical LyP in the same individual further suggests that follicular LyP is merely a histological pattern of LyP involving epithelial adnexae.
Kato
N
N
Department of Dermatology, Hokkaido University School of Medicine, Japan.
Matsue
K
K
D002467:Cell Nucleus / Q000648:ultrastructure; D004848:Epithelium / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006197:Hair / Q000473:pathology; D006801:Humans; D006965:Hyperplasia; D007124:Immunoenzyme Techniques; D017731:Lymphomatoid Papulosis / Q000473:pathology*; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000473:pathology; D012008:Recurrence; D016539:Reed-Sternberg Cells / Q000145:classification / Q000473:pathology; D012075:Remission, Spontaneous; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology