title: Prothrombin activation fragment 1 + 2 and thrombin-antithrombin-III complexes in plasma of patients with essential arterial hypertension.
abstract: Prothrombin activation fragment 1 + 2 (F1 + 2) and thrombin-antithrombin-III complexes (TAT) were measured in plasma of 34 patients with newly diagnosed essential hypertension. The patients with hypertension showed an increase in both F1 + 2 and TAT concentrations. The obtained results point to the intravascular thrombin generation in very early stages of essential hypertension.
authors.affiliation: Department of Haematology, Medical Academy, Białystok, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Kłoczko
authors.forename: M Z
authors.initials: MZ
authors.lastname: Wojtukiewicz
authors.forename: M
authors.initials: M
authors.lastname: Galar
authors.forename: E
authors.initials: E
authors.lastname: Tarasów
authors.forename: J
authors.initials: J
authors.lastname: Jaromin
authors.forename: M
authors.initials: M
authors.lastname: Bielawiec
mesh_terms: D000328:Adult; D000990:Antithrombin III / Q000378:metabolism*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010446:Peptide Fragments / Q000378:metabolism*; D010447:Peptide Hydrolases / Q000378:metabolism*; D011516:Prothrombin / Q000378:metabolism*
chemical_list: D010446:Peptide Fragments; C046193:antithrombin III-protease complex; C045879:prothrombin fragment 1.2; D000990:Antithrombin III; D011516:Prothrombin; D010447:Peptide Hydrolases