Evidence for activation of cyclooxygenase-1/-2 by endogenous nitric oxide in adjuvant arthritic Lewis rats.
Thierse
H J
HJ
Boehringer Mannheim GmbH, Department of Preclinical Research, Mannheim, Germany.
Friebe
W G
WG
Scheuer
W
W
Voelter
W
W
Tibes
U
U
D000818:Animals; D001169:Arthritis, Experimental / Q000201:enzymology* / Q000503:physiopathology; D015232:Dinoprostone / Q000502:physiology; D004789:Enzyme Activation / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology; D008297:Male; D019331:NG-Nitroarginine Methyl Ester / Q000494:pharmacology; D009569:Nitric Oxide / Q000502:physiology*; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors; D010972:Platelet Activating Factor / Q000502:physiology; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism*; D051381:Rats; D011917:Rats, Inbred Lew
D004791:Enzyme Inhibitors; D010972:Platelet Activating Factor; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; D011451:Prostaglandin-Endoperoxide Synthases; D015232:Dinoprostone; D019331:NG-Nitroarginine Methyl Ester