title: Hyperintense subcortical brain alterations in anorexia nervosa.
abstract: OBJECTIVE
  The results of past research have identified changes in brain structure in anorexia nervosa. We observed previously unreported MRI alterations in two cases of anorexia nervosa.
  
  
  METHODS
  For both cases, we reviewed the clinical history, MRI scans and conducted a pertinent literature review.
  
  
  RESULTS
  The MRI brain scans of two patients with the diagnosis of anorexia nervosa revealed evidence of subcortical hyperintense changes on T2-weighted images.
  
  
  CONCLUSIONS
  No previous reports of these findings have been described in the literature on anorexia nervosa to date. Clinical and pathologic correlates associated with these brain observations in anorexia nervosa are discussed.
authors.affiliation: Eating Disorders Unit, Willough at Naples, FL, USA.
authors.forename: K G
authors.initials: KG
authors.lastname: Sieg
authors.forename: M S
authors.initials: MS
authors.lastname: Hidler
authors.forename: M A
authors.initials: MA
authors.lastname: Graham
authors.forename: R L
authors.initials: RL
authors.lastname: Steele
authors.forename: L R
authors.initials: LR
authors.lastname: Kugler
mesh_terms: D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000175:diagnosis / Q000473:pathology; D001921:Brain / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging