title: Treatment of dehiscences and fenestrations around dental implants using resorbable and nonresorbable membranes associated with bone autografts: a comparative clinical study.
abstract: This study was carried out to evaluate the efficacy of poly(lactic acid) and poly(glycolic acid) (PLA/PGA) resorbable membranes in conjunction with autogenous bone grafts when used for the treatment of implant dehiscences and/or fenestrations. Nine patients with a total of 18 implants participated. Nine implants were associated with dehiscences, and 9 with fenestrations; 16 implants were in the maxilla, and 2 in the mandible. Nine defects were treated with PLA/PGA membranes (test group), and the nine were treated with expanded polytetrafluoroethylene (e-PTFE) membranes (control group). Second-stage surgery was performed after 6 to 7 months of healing. Overall results of the regenerative therapy of the 18 defects showed a highly significant (P < .001) defect reduction, with a 93.38% (SD = 15.88) bone fill. A slightly higher percentage of bone fill was found in the e-PTFE group (98.20%) than in the PLA/PGA group (88.56%), but the difference was not statistically significant (P = .207). This study demonstrated that resorbable PLA/PGA membranes can be equally effective as e-PTFE in the treatment of implant dehiscences and fenestrations when associated with autogenous bone chips.
authors.affiliation: Department of Dentistry, University of Milan, San Raffaele Hospital, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Simion
authors.forename: U
authors.initials: U
authors.lastname: Misitano
authors.forename: L
authors.initials: L
authors.lastname: Gionso
authors.forename: A
authors.initials: A
authors.lastname: Salvato
mesh_terms: D000328:Adult; D001672:Biocompatible Materials; D001861:Bone Regeneration; D016025:Bone Transplantation / Q000379:methods; D003758:Dental Implantation, Endosseous / Q000009:adverse effects*; D015921:Dental Implants / Q000009:adverse effects*; D006801:Humans; D007576:Jaw, Edentulous, Partially / Q000601:surgery; D019344:Lactic Acid; D008336:Mandibular Diseases / Q000601:surgery; D008439:Maxillary Diseases / Q000209:etiology / Q000601:surgery*; D008567:Membranes, Artificial; D008875:Middle Aged; D011091:Polyesters; D011100:Polyglycolic Acid; D011108:Polymers; D011138:Polytetrafluoroethylene; D012086:Reoperation; D013529:Surgical Wound Dehiscence / Q000209:etiology / Q000601:surgery*; D014182:Transplantation, Autologous
chemical_list: D001672:Biocompatible Materials; D015921:Dental Implants; D008567:Membranes, Artificial; D011091:Polyesters; D011108:Polymers; D011100:Polyglycolic Acid; D019344:Lactic Acid; C033616:poly(lactide); D011138:Polytetrafluoroethylene