title: Dipole localization in patients with epilepsy using the realistically shaped head model.
abstract: Dipole sources were localized in 3 patients with epilepsy using both the realistically shaped head model and the 3-sphere model. Interictal spikes were recorded from 63 closely spaced scalp electrodes. The scalp, skull, and brain surfaces were digitized from a MRI of each patient's head, and each surface was tessellated by 1600 triangles. Single dipole fits to the EEG were performed using both the realistically shaped head model and the 3-sphere model. The 2 models localized dipoles to positions that differed from one another by 1-3 cm. For dipoles localized to the temporal lobe, the most important difference between models was that the realistically shaped head model localized the dipole lower in the brain than the 3-sphere model. The realistically shaped head model was more in accordance with the ECoG findings than the 3-sphere model.
authors.affiliation: Department of Physics and Astronomy, Vanderbilt University, Nashville, TN 37235, USA. roth@compsci.cas.vanderbilt.edu
authors.forename: B J
authors.initials: BJ
authors.lastname: Roth
authors.forename: D
authors.initials: D
authors.lastname: Ko
authors.forename: I R
authors.initials: IR
authors.lastname: von Albertini-Carletti
authors.forename: D
authors.initials: D
authors.lastname: Scaffidi
authors.forename: S
authors.initials: S
authors.lastname: Sato
mesh_terms: D000293:Adolescent; D000328:Adult; D001921:Brain / Q000473:pathology*; D004569:Electroencephalography; D004833:Epilepsy, Temporal Lobe / Q000473:pathology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008959:Models, Neurological