A young female with a cholangiocarcinoma in the past: is pregnancy allowed?
BACKGROUND
A 28-year-old woman developed a cholangiocarcinoma after using oral contraceptives for eight years. The common bile duct and the gallbladder were removed and four hepaticojejunostomies were performed.


RESULTS
Seven years after surgery no evidence of disease recurrence is detectable and the patient wants advice regarding her wish for pregnancy.


CONCLUSIONS
The possible role of oestrogens in the development of cholangiocarcinoma makes it difficult to give an adequate advice. As in patients with breast cancer in the past, it seems reasonable to admit pregnancy in our patient, because of a disease-free interval of longer than five years.
Temizkan
M
M
Department of Internal Medicine, Ikazia Hospital, Rotterdam, The Netherlands.
Ouwendijk
J T
JT
Middelkoop
M P
MP
Blankenstein
M
M
ten Kate
F J
FJ
Tytgat
G N
GN
D000328:Adult; D001650:Bile Duct Neoplasms / Q000601:surgery*; D001653:Bile Ducts, Intrahepatic; D018281:Cholangiocarcinoma / Q000601:surgery*; D003376:Counseling; D005260:Female; D006801:Humans; D011247:Pregnancy