Human chagasic disease is not associated with an antiheart humoral response.
An inflammatory cardiomyopathy occurs in humans with chronic Trypanosoma cruzi infection (Chagas' disease). This study finds that T. cruzi infection is not associated with the production of cardiac-specific autoantibodies in humans with cardiac manifestations.
Baig
M K
MK
Department of Cardiological Sciences, St. George's Hospital Medical School, London, United Kingdom.
Salomone
O
O
Caforio
A L
AL
Goldman
J H
JH
Amuchastegui
M
M
Caiero
T
T
McKenna
W J
WJ
D000328:Adult; D000368:Aged; D000818:Animals; D000953:Antigens, Protozoan / Q000097:blood*; D002598:Chagas Cardiomyopathy / Q000276:immunology*; D014355:Chagas Disease / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000276:immunology*; D009218:Myosins / Q000276:immunology*
D000953:Antigens, Protozoan; D009218:Myosins