Expression of the LFA-1 beta molecule on peripheral blood leukocytes of patients with early-onset periodontitis: effects of dental plaque microbes.
The effect of dental plaque bacteria on LFA-1 beta expression on peripheral blood leukocytes was studied in 20 patients with early-onset periodontitis and in 10 healthy controls. Stimulation of PMN with selected dental plaque bacteria which play a role in the pathogeny of periodontitis significantly increased the expression of LFA-1 beta in the group of patients as compared with the controls.
Procházková
J
J
Department of Immunology, Institute of Dental Research, Prague.
Bártová
J
J
Bílková
A
A
Kruzík
P
P
Krejsa
O
O
Dusková
J
J
Mrklas
L
L
D016924:Actinomyces viscosus / Q000276:immunology / Q000472:pathogenicity; D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D016976:Aggregatibacter actinomycetemcomitans / Q000276:immunology / Q000472:pathogenicity; D001422:Bacterial Adhesion; D003773:Dental Plaque / Q000382:microbiology*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D007962:Leukocytes / Q000276:immunology*; D016169:Lymphocyte Function-Associated Antigen-1 / Q000097:blood*; D008297:Male; D009616:Nocardia asteroides / Q000276:immunology / Q000472:pathogenicity; D010518:Periodontitis / Q000209:etiology / Q000276:immunology* / Q000382:microbiology*; D016966:Porphyromonas gingivalis / Q000276:immunology / Q000472:pathogenicity
D016169:Lymphocyte Function-Associated Antigen-1