title: Non-operative management of a splenic laceration in a patient with the Proteus syndrome.
abstract: An adult patient with the Proteus syndrome sustained a grade III splenic laceration after falling off a horse. Clinical features of this rare disorder include subcutaneous and visceral hamartomatous tumours. The patient also suffered from chronic intravascular coagulation associated with extensive haemangiomatosis (Kasabach-Merritt syndrome). Considering the visceral anomalies and abnormal coagulation, a non-operative approach was preferred despite considerable transfusion requirement, and the patient successfully underwent embolisation of the splenic artery. This is the first reported case of splenic injury in a patient with Proteus syndrome.
authors.affiliation: Department of Surgery, University Hospital, Gent University Medical School, Belgium.
authors.forename: W
authors.initials: W
authors.lastname: Ceelen
authors.forename: J
authors.initials: J
authors.lastname: De Waele
authors.forename: M
authors.initials: M
authors.lastname: Kunnen
authors.forename: B
authors.initials: B
authors.lastname: de Hemptinne
mesh_terms: D000328:Adult; D004621:Embolization, Therapeutic; D006801:Humans; D008297:Male; D016715:Proteus Syndrome / Q000150:complications*; D013154:Spleen / Q000293:injuries*; D014949:Wounds, Nonpenetrating / Q000628:therapy*