Phosphorylation sensitivity of the commonly used anti-p185neu/erbB2 monoclonal antibody clone 3B5 suggests selective usage of autophosphorylation sites.
DiGiovanna
M P
MP
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06510, USA. digiovanna@biomed.med.yale.edu
D000911:Antibodies, Monoclonal / Q000737:chemistry / Q000378:metabolism*; D001665:Binding Sites; D006801:Humans; D010766:Phosphorylation; D011233:Precipitin Tests; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000737:chemistry / Q000276:immunology* / Q000302:isolation & purification; D014407:Tumor Cells, Cultured
D000911:Antibodies, Monoclonal; D018719:Erb-b2 Receptor Tyrosine Kinases