title: Fucosylation of synthetic oligosaccharides--plant xyloglucan fragments--by mammalian and amphibian fucosyltransferases.
abstract: Liver and oviduct of frogs Rana temporaria and Xenopus laevis were shown to possess the activity of beta-galactoside alpha 1-2-fucosyltransferase. Extracts of these tissues as well as porcine and rat submaxillary gland homogenates catalyze the fucosylation of synthetic plant xyloglucan fragments, the disaccharide D-Gal(beta 1-2)D-Xyl and the tetrasaccharide D-Gal(beta 1-2)D-Xyl(alpha 1-6)D-Glc(beta 1-4)D-Glc; the active preparations can be used for enzymatic synthesis of biologically active oligosaccharides.
authors.affiliation: Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia.
authors.forename: T N
authors.initials: TN
authors.lastname: Druzhinina
authors.forename: O V
authors.initials: OV
authors.lastname: Sizova
authors.forename: V N
authors.initials: VN
authors.lastname: Shibaev
mesh_terms: D000818:Animals; D005643:Fucose / Q000378:metabolism*; D005647:Fucosyltransferases / Q000378:metabolism*; D005936:Glucans; D009844:Oligosaccharides / Q000378:metabolism*; D010944:Plants / Q000378:metabolism*; D011134:Polysaccharides / Q000378:metabolism*; D011896:Rana temporaria; D051381:Rats; D013363:Submandibular Gland / Q000201:enzymology / Q000378:metabolism; D013552:Swine; D014982:Xenopus laevis; D014990:Xylans
chemical_list: D005936:Glucans; D009844:Oligosaccharides; D011134:Polysaccharides; D014990:Xylans; D005643:Fucose; C029353:xyloglucan; D005647:Fucosyltransferases