Arterial blood pressure and effective peritoneal blood flow during intermittent peritoneal dialysis.
Our earlier studies indicate that effective peritoneal blood flow (EPBF) during intermittent peritoneal dialysis (IPD) does not depend on gender, age, body mass, renal disease leading to uremia and duration of IPD. Thus, a cause of differences in EPBF observed in uremic patients during IPD is still not clear. The aim of present studies is an evaluation of relationship between arterial blood pressure and EPBF calculated as diffusive mass transfer coefficient of CO2. Studies were performed in 20 patients in the age of 47 +/- 14 (x +/- SD) years, treated with IPD during 4.3 +/- 3.6 months. EPBF and arterial blood pressure were evaluated in the middle of dialysis. Mean arterial pressure was calculated from systolic and diastolic pressure. In patients (n = 10) with greater EPBF (291 +/- 99 ml/min) systolic, diastolic and mean pressures were respectively 166 +/- 24, 100 +/- 20 and 122 +/- 20 mmHg. In patients (n = 10) with smaller EPBF (154 +/- 27 ml/min) respective pressure were 160 +/- 12, 91 +/- 9 and 114 +/- 8 mmHg. The highest but insignificant correlation was found between EPBF and diastolic blood pressure (r = 0.310, n = 20). Patients with significantly higher diastolic (108 +/- 16 mmHg, n = 9, v. 85 +/- 6 mmHg, n = 11) and mean blood pressure (129 +/- 17 v. 108 +/- 2 mmHg) showed insignificantly greater EPBF (260 +/- 121 v. 192 +/- 63 ml/min). Our studies indicate that EPBF during IPD cannot significantly depend on blood pressure.
Grzegorzewska
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Department of Nephrology, K. Marcinkowski Academy of Medicine, Poznań, Poland.
Mariak
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I
D000328:Adult; D001794:Blood Pressure; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis; D010537:Peritoneum / Q000098:blood supply*; D014511:Uremia / Q000503:physiopathology* / Q000628:therapy