A case of intrauterine medical treatment for cystic hygroma.
We report the first case of an intrauterine treatment for cystic hygroma. Guided by ultrasonography, we first removed intracystic fluid from two cysts and then injected OK-432 into each fetal cyst at 21 and 28 weeks of gestation. No re-enlargement of the cysts was subsequently observed. At 38 weeks of gestation, a male infant was delivered transvaginally. Only a slight skin fold was observed in the nuchal area of the neonate, indicating the effectiveness of OK-432 for the intrauterine treatment of cystic hygroma.
Watari
H
H
Department of Obstetrics and Gynecology, Hokkaido University School of Medicine, Sapporo, Japan.
Yamada
H
H
Fujino
T
T
Okuyama
K
K
Sagawa
T
T
Makinoda
S
S
Fujimoto
S
S
D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D018191:Lymphangioma, Cystic / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008297:Male; D010844:Picibanil / Q000008:administration & dosage / Q000627:therapeutic use*; D011247:Pregnancy; D016216:Ultrasonography, Prenatal
D000970:Antineoplastic Agents; D010844:Picibanil