title: Real time monitoring of laser-induced thermal changes in cartilage in vitro by using snapshot FLASH.
abstract: Snapshot FLASH imaging has been applied to study the spatial and temporal spreading of thermal changes caused by a Holmium:YAG laser in patella cartilage in vitro at 7 T. The temperature dependence of the proton resonance frequency was used to demonstrate the thermal energy deposition. A series of cartilage images, with a time resolution of 512 ms and a spatial resolution of 400 x 200 microm, showed dynamic changes of the temperature-related image phase in the regions irradiated by the laser.
authors.affiliation: Physikalisches Institüt, Lehrstuhl für Experimentelle Physik V, Universität Wurzbürg.
authors.forename: P M
authors.initials: PM
authors.lastname: Jakob
authors.forename: C
authors.initials: C
authors.lastname: Hendrich
authors.forename: T
authors.initials: T
authors.lastname: Breitling
authors.forename: A
authors.initials: A
authors.lastname: Schäfer
authors.forename: A
authors.initials: A
authors.lastname: Berden
authors.forename: A
authors.initials: A
authors.lastname: Haase
mesh_terms: D002358:Cartilage, Articular / Q000473:pathology* / Q000528:radiation effects; D006801:Humans; D066298:In Vitro Techniques; D007719:Knee Joint; D007834:Lasers; D008279:Magnetic Resonance Imaging / Q000379:methods*; D013696:Temperature