Effect of high-fat cholesterol enriched diets on hypolipemic action of Oenothera paradoxa oil in rats. Part 2. Blood serum and liver fatty acids.
The effect of Oenothera paradoxa oil on blood serum and liver fatty acids composition in rats was studied. Rats were fed high-fat diets containing 15% of lard or sunflower oil with or without 0.5% of cholesterol. Soybean protein isolate (27%) was the source of proteins. Intake of Oe. paradoxa oil resulted in increase of levels of gamma-linolenic acid (GLA) and linoleic acid (LA) in blood serum and liver of experimental animals. The effect of Oe. paradoxa oil on blood serum and liver fatty acids composition depended mainly on the type and to the lower degree on the amount of fat in a diet. The addition of cholesterol did not change the influence of examined oil on the composition of fatty acids.
Grajeta
H
H
Wroclaw University of Medicine, Department of Food Science and Nutrition, Poland.
Biernat
J
J
D000818:Animals; D002784:Cholesterol / Q000097:blood / Q000378:metabolism; D002791:Cholesterol, Dietary / Q000494:pharmacology*; D004041:Dietary Fats / Q000494:pharmacology*; D005227:Fatty Acids / Q000097:blood / Q000378:metabolism*; D005228:Fatty Acids, Essential / Q000494:pharmacology*; D005260:Female; D000960:Hypolipidemic Agents / Q000494:pharmacology*; D008041:Linoleic Acids; D008099:Liver / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D031665:Oenothera biennis; D010938:Plant Oils; D051381:Rats; D011915:Rats, Inbred BUF; D017965:gamma-Linolenic Acid
D002791:Cholesterol, Dietary; D004041:Dietary Fats; D005227:Fatty Acids; D005228:Fatty Acids, Essential; D000960:Hypolipidemic Agents; D008041:Linoleic Acids; D010938:Plant Oils; C028498:evening primrose oil; D017965:gamma-Linolenic Acid; D002784:Cholesterol