Could L-carnitine be an acute energy inducer in catabolic conditions?
Serum free carnitine levels in five children (aged between 2.5 months and 4 years) with the findings of septic shock without disseminated intravascular coagulopathy and seven children (aged between 1.5 and 6.5 years) with the first attack of idiopathic status epilepticus were compared with those of eight healthy children (aged between 2.5 months and 5 years). Serum free carnitine levels showed a statistically significant decrease in the sepsis (mean 51.5 +/- 19 mg/L) and status epilepticus groups (mean 4.1 +/- 12.4 mg/L) (P = 0.006 and P = 0.001, respectively) when compared with the controls (mean 90.8 +/- 17.2 mg/L).
Keskin
S
S
Pediatrics Department, Cerrahpasa University, Istanbul, Turkey.
Seven
A
A
Mert
M
M
Akalp
F
F
Yurdakul
F
F
Candan
G
G
D002331:Carnitine / Q000378:metabolism*; D002648:Child; D002675:Child, Preschool; D004734:Energy Metabolism / Q000502:physiology*; D004827:Epilepsy / Q000378:metabolism*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012772:Shock, Septic / Q000378:metabolism*
D002331:Carnitine