Successful treatment with topical PUVA of nodular cutaneous plasmacytosis associated with alopecia of the scalp.
We obtained a successful response to PUVA therapy in a 51-year-old Japanese man who had multiple nodules of the trunk, extremities and scalp along with polyclonal hypergammaglobulinaemia; the scalp lesions were associated with extensive alopecia. Examination of skin biopsies showed a dense infiltrate of mature plasma cells in the dermis and hair follicles; no systemic disease or functional involvement of other organs was detected. The clinical and histological findings were compatible with cutaneous plasmacytosis and treatment with topical PUVA gradually reduced the size and number of the lesions.
Kaneda
M
M
Department of Dermatology, School of Medicine, Chiba University, Japan.
Kuroda
K
K
Fujita
M
M
Shinkai
H
H
D000505:Alopecia / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D008297:Male; D008875:Middle Aged; D011701:PUVA Therapy; D010950:Plasma Cells / Q000276:immunology*; D012871:Skin Diseases / Q000150:complications / Q000188:drug therapy* / Q000276:immunology
D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M