title: Malononitrilamides inhibit T- and B-cell responsiveness in different species.
authors.affiliation: Research Laboratories of Hoechst Marion Roussel, Marburg, Wiesbaden, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Kurrle
authors.forename: E
authors.initials: E
authors.lastname: Ruuth
authors.forename: R
authors.initials: R
authors.lastname: Bartlett
authors.forename: L
authors.initials: L
authors.lastname: Lauffer
authors.forename: H U
authors.initials: HU
authors.lastname: Schorlemmer
mesh_terms: D000480:Alkynes; D000814:Aniline Compounds / Q000494:pharmacology*; D000818:Animals; D001402:B-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D002415:Cats; D002460:Cell Line; D002478:Cells, Cultured; D003437:Crotonates; D004285:Dogs; D006801:Humans; D006885:Hydroxybutyrates / Q000494:pharmacology*; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007555:Isoxazoles; D008213:Lymphocyte Activation / Q000187:drug effects; D051379:Mice; D009570:Nitriles / Q000494:pharmacology*; D011323:Primates; D051381:Rats; D012756:Sheep; D013045:Species Specificity; D013552:Swine; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D014052:Toluidines
chemical_list: D000480:Alkynes; D000814:Aniline Compounds; D003437:Crotonates; D006885:Hydroxybutyrates; D007166:Immunosuppressive Agents; D007555:Isoxazoles; D009570:Nitriles; D014052:Toluidines; C102911:X 910279; C115284:2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide; C527525:teriflunomide