[Serum apolipoprotein B (apoB) in patients with hypothyroidism].
The concentrations of serum lipids (total cholesterol, triacylglycerols), apolipoprotein B and thyroid hormones (thyroxine, triiodthyronine) were observed before and during hormone replacement therapy by thyroid hormones in 24 hypothyroid patients (18 women and 6 men) until the state of euthyroidism was reached. The observed parameters regained standard values gradually, while the concentration of apolipoprotein B recovered to normal as the last among them. Therefore the authors recommend to consider apolipoprotein B concentration in serum as a risk factor of the development of arteriosclerosis in hypothyroid patients, the value of apolipoprotein B concentration can serve as a guideline in choosing the optimal hormone substitution therapy. (Tab. 1, Fig. 1, Ref. 5.).
Oravec
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II. interná klinika Lekárskej fakulty Univerzity Komenského, Bratislave, Slovakia.
Oravec
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D000328:Adult; D000368:Aged; D001055:Apolipoproteins B / Q000097:blood*; D001161:Arteriosclerosis / Q000097:blood / Q000209:etiology; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000097:blood* / Q000188:drug therapy; D008055:Lipids / Q000097:blood; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
D001055:Apolipoproteins B; D008055:Lipids