title: In vivo wall shear stress measured by magnetic resonance velocity mapping in the normal human abdominal aorta.
abstract: OBJECTIVE
  To apply a new non-invasive method for quantification of in vivo wall shear stress (WSS) by magnetic resonance (MR) FAcE velocity mapping and measure WSS in the human abdominal aorta.
  
  
  METHODS
  Prospective, open study.
  
  
  METHODS
  Six volunteers.
  
  
  METHODS
  MR FAcE velocity method was developed for measurements of mean, maximum, minimum WSS and oscillating shear index (OSI) values at the anterior and posterior walls of suprarenal and infrarenal abdominal aorta.
  
  
  RESULTS
  The mean, maximum and minimum WSS values were 0.63/0.28, 4.07/2.72 and -0.71/-1.00 N/m2, respectively, in the suprarenal/infrarenal aorta. The mean WSS was 0.35 N/m2 (p < 0.001) and the maximum WSS was 1.36 N/m2 (p < 0.0001) lower in the infrarenal aorta than in the suprarenal aorta. Mean, maximum minimum WSS and OSI values in the infrarenal position differed (p < 0.01) between the anterior and posterior walls.
  
  
  CONCLUSIONS
  WSS can be determined in vivo by MR FAcE velocity technique. Since the lowest WSS values were measured in the infrarenal, posterior blood-to-wall interface, the theory of more pronounced atherosclerosis development in low and oscillating WSS domains was not contradicted by the results of the present study.
authors.affiliation: Department of Cardiothoracic and Vascular Surgery T, Aarhus University Hospital, Skejby Sygehus, Denmark.
authors.forename: S
authors.initials: S
authors.lastname: Oyre
authors.forename: E M
authors.initials: EM
authors.lastname: Pedersen
authors.forename: S
authors.initials: S
authors.lastname: Ringgaard
authors.forename: P
authors.initials: P
authors.lastname: Boesiger
authors.forename: W P
authors.initials: WP
authors.lastname: Paaske
mesh_terms: D000328:Adult; D001012:Aorta, Abdominal / Q000033:anatomy & histology / Q000502:physiology*; D001161:Arteriosclerosis / Q000209:etiology; D001783:Blood Flow Velocity / Q000502:physiology; D018056:Hemorheology; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D011446:Prospective Studies; D013314:Stress, Mechanical