Relationship between the development of blindness in Churg-Strauss syndrome and anti-myeloperoxidase antibodies.
Occular involvement is infrequent and blindness rare in Churg-Strauss syndrome. We describe a patient with Churg-Strauss syndrome who presented with blindness. This was associated with the appearance of circulating autoantibodies to myeloperoxidase.
Sutcliffe
N
N
Bloomsbury Rheumatology Unit/Division of Rheumatology, Department of Medicine, University College London.
Morris
V
V
Gomperts
B
B
Brazier
D J
DJ
Isenberg
D A
DA
Cambridge
G
G
D001323:Autoantibodies / Q000032:analysis*; D015415:Biomarkers; D001766:Blindness / Q000201:enzymology / Q000209:etiology*; D015267:Churg-Strauss Syndrome / Q000150:complications* / Q000201:enzymology; D004804:Eosinophils / Q000502:physiology; D005654:Fundus Oculi; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D009195:Peroxidase / Q000276:immunology*
D001323:Autoantibodies; D015415:Biomarkers; D009195:Peroxidase