Phosphatidylinositol-3-kinase pathway is stimulated by fungal lipid containing cocoa butter equivalents (CBE) in FMet-Leu-Phe (FMLP)- and phorbolester (PMA)-challenged human neutrophils.
Roux
M P
MP
Department of Gynecology, University Medical Hospital Benjamin Franklin, Berlin, FRG.
Kock
J L
JL
Nigam
S
S
D002099:Cacao / Q000737:chemistry*; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005658:Fungi / Q000737:chemistry*; D006801:Humans; D066298:In Vitro Techniques; D008055:Lipids / Q000737:chemistry / Q000494:pharmacology*; D009240:N-Formylmethionine Leucyl-Phenylalanine / Q000494:pharmacology*; D009504:Neutrophils / Q000187:drug effects / Q000201:enzymology*; D019869:Phosphatidylinositol 3-Kinases; D017853:Phosphotransferases (Alcohol Group Acceptor) / Q000378:metabolism*; D011493:Protein Kinase C / Q000037:antagonists & inhibitors; D016897:Respiratory Burst / Q000187:drug effects; D019311:Staurosporine / Q000494:pharmacology; D013481:Superoxides / Q000378:metabolism; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology*
D004791:Enzyme Inhibitors; D008055:Lipids; D013481:Superoxides; D009240:N-Formylmethionine Leucyl-Phenylalanine; D019869:Phosphatidylinositol 3-Kinases; D017853:Phosphotransferases (Alcohol Group Acceptor); D011493:Protein Kinase C; D019311:Staurosporine; D013755:Tetradecanoylphorbol Acetate