Subclavian artery stenosis presenting as posterior cerebrovascular events after adjuvant radiotherapy for breast cancer.
Late radiotherapy-induced arteriopathy is recognized as an important cause of cerebrovascular disease in patients treated with radiotherapy, usually for head and neck cancers. This case report is an example of radiotherapy-induced left subclavian artery stenosis, which resulted in serious posterior cerebral circulation events after adjuvant radiotherapy for carcinoma of the left breast. In view of the relatively good long term outlook for this disease, it is important to recognize and consider early medical or surgical intervention of such arterial lesions. In this patient, earlier intensive investigations probably would have prevented disabling iatrogenic morbidity.
Lewis
J
J
Newcastle General Hospital, Newcastle upon Tyne, UK.
Roberts
J T
JT
Gholkar
A
A
D000328:Adult; D001157:Arterial Occlusive Diseases / Q000209:etiology*; D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000532:radiotherapy* / Q000601:surgery; D002561:Cerebrovascular Disorders / Q000209:etiology*; D005260:Female; D006801:Humans; D015413:Mastectomy, Simple; D011878:Radiotherapy / Q000009:adverse effects; D018714:Radiotherapy, Adjuvant; D013348:Subclavian Artery