Biodegradation of lantadene A, the pentacyclic triterpenoid hepatotoxin by Pseudomonas pickettii.
A bacterial strain capable of biodegradation of lantadene A (22 beta-angeloyloxy-3-oxoolean-12-en-28-oic acid) has been isolated from soil using lantadene A as the sole carbon source. The organism is rod shaped, Gram negative, motile and has been identified as Pseudomonas pickettii. This is the first report of the biodegradation of a pentacyclic triterpenoid.
Sharma
O P
OP
Biochemistry Laboratory, Indian Veterinary Research Institute, Palampur, India.
Dawra
R K
RK
Datta
A K
AK
Kanwar
S S
SS
D000818:Animals; D001673:Biodegradation, Environmental; D001711:Biotransformation; D008099:Liver / Q000187:drug effects*; D015394:Molecular Structure; D009828:Oleanolic Acid / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity; D010947:Plants, Toxic; D011549:Pseudomonas / Q000254:growth & development / Q000302:isolation & purification / Q000378:metabolism*; D012988:Soil Microbiology; D014118:Toxins, Biological / Q000737:chemistry / Q000378:metabolism* / Q000633:toxicity*
D014118:Toxins, Biological; D009828:Oleanolic Acid; C019074:rehmannic acid