Domestic fungal viable propagules and sensitization in children with IgE mediated allergic diseases.
In order to study the possible relationship between domestic fungal exposure and sensitization to fungi, the homes of 20 children with allergic diseases (mainly bronchial asthma) were inspected for visible fungal growth and airborne viable fungal propagules were sampled. Inclusion criterion was sensitization to at least one of the tested fungi as shown by proof of specific IgE in serum. Twelve of 19 homes (63%) revealed a considerable amount of viable fungal propagules and/or visible fungal growth. Penicillium, Cladosporium, Aspergillus, Mycelia sterilia and yeasts were most prevalent. There was no clear-cut relationship to serologically proven sensitization.
Dill
I
I
Technical University, Berlin, Germany.
Niggemann
B
B
D000293:Adolescent; D016902:Air Pollution, Indoor / Q000009:adverse effects / Q000032:analysis; D000485:Allergens / Q000032:analysis / Q000276:immunology; D001249:Asthma / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D004783:Environmental Microbiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005658:Fungi / Q000254:growth & development / Q000276:immunology*; D006798:Housing; D006801:Humans; D007114:Immunization; D007073:Immunoglobulin E / Q000032:analysis; D008297:Male; D012130:Respiratory Hypersensitivity / Q000276:immunology*
D000485:Allergens; D007073:Immunoglobulin E