title: [Prevention of opportunistic infections in HIV seropositive patients. Prevention of parasitic infections].
abstract: PNEUMOCYSTIS CARINII PNEUMONIA: Below a threshold 200 CD4 cont, the risk of P. carinii infection is sufficiently high to propose systematic prophylaxis. Trimethoprim-sulfamethoxazole is the treatment of choice for primary and secondary prevention. Pentamidine-isothionate can also be used, possibly with dapsone. TOXOPLASMOSIS: There is a consensus on primary prevention in patients with positive toxoplasmosis serology whose CD4 count is under 100. Trimethoprime-sulfamethoxazole is the first intention drug, but poor tolerance may require conversion to dapsone-pyrimethamine. For secondary prophylaxis, the consensus is for life-long treatment with low-doses after initiating treatment with sulfadiazine and pyrimethamine. LEISHMANIASIS: Secondary prevention is reasonable using monthly infusions of pentamidine.
authors.affiliation: Service de Médecine interne, Hôpital Avicenne, Bobigny.
authors.forename: P
authors.initials: P
authors.lastname: Casassus
authors.forename: B
authors.initials: B
authors.lastname: Padrazzi
authors.forename: F
authors.initials: F
authors.lastname: Lhote
authors.forename: B
authors.initials: B
authors.lastname: Jarrousse
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy / Q000469:parasitology / Q000517:prevention & control*; D006801:Humans; D007896:Leishmaniasis / Q000188:drug therapy / Q000517:prevention & control; D010272:Parasitic Diseases / Q000188:drug therapy / Q000517:prevention & control*; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy / Q000517:prevention & control; D014123:Toxoplasmosis / Q000188:drug therapy / Q000517:prevention & control