title: Deletion polymorphism in the angiotensin-converting enzyme gene is not associated with hypertension in a Gulf Arab population.
abstract: We have studied an insertion/deletion dimorphism in the human angiotensin-converting enzyme gene amongst UAE nationals from the Abu Dhabi Emirate. Our findings show lack of association between the I/D allele marker system and clinical diagnosis of essential hypertension, suggesting that variations of the angiotensin-converting enzyme gene do not play a major role in the determination of elevated blood pressure in this Arab population. This agrees with results reported on other ethnic groups.
authors.affiliation: Department of Pathology, Faculty of Medicine & Health Sciences, Al Ain, United Arab Emirates.
authors.forename: P M
authors.initials: PM
authors.lastname: Frossard
authors.forename: E N
authors.initials: EN
authors.lastname: Obineche
authors.forename: Y I
authors.initials: YI
authors.lastname: Elshahat
authors.forename: G G
authors.initials: GG
authors.lastname: Lestringant
mesh_terms: D000483:Alleles; D005260:Female; D017353:Gene Deletion; D005819:Genetic Markers; D006801:Humans; D006973:Hypertension / Q000208:ethnology / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D007703:Peptidyl-Dipeptidase A / Q000235:genetics*; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D017422:Sequence Analysis, DNA
chemical_list: D005819:Genetic Markers; D007703:Peptidyl-Dipeptidase A