title: Mortality among benzene-exposed workers in China.
abstract: A large cohort of 74,828 benzene-exposed and 35,805 nonexposed workers employed between 1972 and 1987 in 12 cities in China was followed to determine mortality from all causes. Benzene-exposed study subjects were employed in a variety of occupations including coating applications, and rubber, chemical, and shoe production. Mortality was slightly increased among workers with greater cumulative exposure to benzene (ptrend < 0.05), but this excess was largely due to cancer deaths (ptrend < 0.01). Deaths due to lymphatic and hematopoietic malignancies (ptrend = 0.01) and lung cancer (ptrend = 0.01) increased with increasing cumulative exposure to benzene. Investigations continue to relate benzene exposure to specific lymphatic and hematopoietic malignancies and other causes of death.
authors.affiliation: Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-7368, USA. hayesr@epndce.nci.nih.gov
authors.forename: R B
authors.initials: RB
authors.lastname: Hayes
authors.forename: S N
authors.initials: SN
authors.lastname: Yin
authors.forename: M
authors.initials: M
authors.lastname: Dosemeci
authors.forename: G L
authors.initials: GL
authors.lastname: Li
authors.forename: S
authors.initials: S
authors.lastname: Wacholder
authors.forename: W H
authors.initials: WH
authors.lastname: Chow
authors.forename: N
authors.initials: N
authors.lastname: Rothman
authors.forename: Y Z
authors.initials: YZ
authors.lastname: Wang
authors.forename: T R
authors.initials: TR
authors.lastname: Dai
authors.forename: X J
authors.initials: XJ
authors.lastname: Chao
authors.forename: Z L
authors.initials: ZL
authors.lastname: Jiang
authors.forename: P Z
authors.initials: PZ
authors.lastname: Ye
authors.forename: H B
authors.initials: HB
authors.lastname: Zhao
authors.forename: Q R
authors.initials: QR
authors.lastname: Kou
authors.forename: W Y
authors.initials: WY
authors.lastname: Zhang
authors.forename: J F
authors.initials: JF
authors.lastname: Meng
authors.forename: J S
authors.initials: JS
authors.lastname: Zho
authors.forename: X F
authors.initials: XF
authors.lastname: Lin
authors.forename: C Y
authors.initials: CY
authors.lastname: Ding
authors.forename: C Y
authors.initials: CY
authors.lastname: Li
authors.forename: Z N
authors.initials: ZN
authors.lastname: Zhang
authors.forename: D G
authors.initials: DG
authors.lastname: Li
authors.forename: L B
authors.initials: LB
authors.lastname: Travis
authors.forename: W J
authors.initials: WJ
authors.lastname: Blot
authors.forename: M S
authors.initials: MS
authors.lastname: Linet
mesh_terms: D001554:Benzene / Q000633:toxicity*; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007938:Leukemia / Q000139:chemically induced / Q000401:mortality; D008175:Lung Neoplasms / Q000139:chemically induced / Q000401:mortality; D008223:Lymphoma / Q000139:chemically induced / Q000401:mortality; D008297:Male; D009369:Neoplasms / Q000139:chemically induced / Q000401:mortality; D009784:Occupational Diseases / Q000139:chemically induced* / Q000401:mortality*; D016273:Occupational Exposure; D012307:Risk Factors
chemical_list: D001554:Benzene