Ischemic hepatitis associated with toxic epidermal necrolysis in a cirrhotic patient treated with cefuroxime.
Ischemic hepatitis is rare in patients with liver cirrhosis and is usually precipitated by hypotension due to gastrointestinal bleeding. We describe a cirrhotic patient who developed ischemic hepatitis as a consequence of toxic epidermal necrolysis (TEN) caused by cefuroxime.
Yossepowitch
O
O
Department of Medicine, Hadassah University Hospital, POB: 12000, Jerusalem, Israel.
Amir
G
G
Safadi
R
R
Lossos
I
I
D000368:Aged; D000369:Aged, 80 and over; D002444:Cefuroxime / Q000009:adverse effects* / Q000627:therapeutic use; D002511:Cephalosporins / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006505:Hepatitis / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007511:Ischemia / Q000209:etiology* / Q000473:pathology; D008099:Liver / Q000098:blood supply*; D008103:Liver Cirrhosis / Q000188:drug therapy; D013262:Stevens-Johnson Syndrome / Q000150:complications* / Q000473:pathology
D002511:Cephalosporins; D002444:Cefuroxime