title: Endemic goitre in a rural community of KwaZulu-Natal.
abstract: OBJECTIVE
  To quantity the prevalence of goitre and iodine deficiency.
  
  
  METHODS
  Ndunakazi, a rural community of approximately 8000 people in KwaZulu-Natal.
  
  
  METHODS
  A cross-sectional community-based survey and a school-based survey.
  
  
  METHODS
  The 127 mothers and 114 children aged 6-11 years, selected during the cross-sectional survey, and 304 children aged 5-14 years, from the school-based survey.
  
  
  METHODS
  Urinary iodine levels and thyroid size were determined and categorised according to guidelines proposed jointly by the WHO, UNICEF and the ICCIDD. Z-score anthropometric indicators were calculated, and mid-year exam marks of goitrous and non-goitrous pupils for Zulu and mathematics were compared.
  
  
  RESULTS
  In school-aged children, both surveys demonstrated a goitre prevalence in the 20-29.9% range and a median urinary iodine level in the 2-4.9 micrograms/dl range, indicating iodine deficiency of moderate severity. Goitrous subjects scored consistently worse in their Zulu exam papers than those without goitre. Stunting was not more prevalent than in the rest of KwaZulu-Natal. Iodised salt was not available in any of the three community shops.
  
  
  CONCLUSIONS
  This level of iodine deficiency in children can adversely affect their neuropsycho-intellectual development. Factors contributing to deficient iodine intake in Ndunakazi are present in many rural areas, and South Africa cannot afforded to be overly confident about the apparent absence of iodine deficiency as a public health problem.
authors.affiliation: Department of Community Health, University of Steffenbosch Tygerberg, W Cape.
authors.forename: J G
authors.initials: JG
authors.lastname: Benedé
authors.forename: A
authors.initials: A
authors.lastname: Oelofse
authors.forename: M E
authors.initials: ME
authors.lastname: van Stuijvenberg
authors.forename: P L
authors.initials: PL
authors.lastname: Jooste
authors.forename: M J
authors.initials: MJ
authors.lastname: Weight
authors.forename: A J
authors.initials: AJ
authors.lastname: Benadé
mesh_terms: D000293:Adolescent; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006043:Goiter, Endemic / Q000097:blood / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D007455:Iodine / Q000172:deficiency* / Q000652:urine; D008297:Male; D015995:Prevalence; D012424:Rural Population; D013019:South Africa / Q000453:epidemiology
chemical_list: D007455:Iodine