Human CD46 but not CD59 in transgenic mice protects against hyperacute rejection evoked by ex vivo perfusion with human serum.
Marquet
R L
RL
Department of Surgery, Imutran, Cambridge, UK.
van Stijn
I
I
van den Tol
P M
PM
Bonthuis
F
F
Yannoutsos
N
N
IJzermans
J N
JN
D000818:Animals; D015703:Antigens, CD / Q000235:genetics / Q000276:immunology*; D001769:Blood; D018957:CD59 Antigens / Q000235:genetics / Q000276:immunology*; D018244:Chromosomes, Artificial, Yeast; D003169:Complement Inactivator Proteins / Q000276:immunology; D006084:Graft Rejection / Q000276:immunology / Q000517:prevention & control*; D006321:Heart / Q000502:physiology*; D006801:Humans; D066298:In Vitro Techniques; D051916:Membrane Cofactor Protein; D008562:Membrane Glycoproteins / Q000235:genetics / Q000276:immunology*; D051379:Mice; D008822:Mice, Transgenic; D010477:Perfusion; D013997:Time Factors
D015703:Antigens, CD; C497857:CD46 protein, human; D018957:CD59 Antigens; D003169:Complement Inactivator Proteins; C497859:Mcp protein, mouse; D051916:Membrane Cofactor Protein; D008562:Membrane Glycoproteins