A novel inhibitor of nuclear factor-kappa B and activator protein-1 transcription factors in T cells suppresses host-versus-graft alloreactivity in vivo.
Morikawa
M
M
Department of Cardiothoracic Surgery, Stanford University Medical Center, California 94305-5247, USA.
Shorthouse
R A
RA
Suto
M J
MJ
Goldman
M E
ME
Morris
R E
RE
D000818:Animals; D016572:Cyclosporine / Q000494:pharmacology; D006087:Graft vs Host Reaction; D006965:Hyperplasia; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007519:Isoantigens / Q000276:immunology; D008198:Lymph Nodes / Q000276:immunology* / Q000473:pathology; D017710:Lymphocyte Transfusion; D051379:Mice; D008807:Mice, Inbred BALB C; D008809:Mice, Inbred C3H; D016328:NF-kappa B / Q000037:antagonists & inhibitors*; D009930:Organic Chemicals; D013154:Spleen; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D013997:Time Factors; D018808:Transcription Factor AP-1 / Q000037:antagonists & inhibitors*; D014184:Transplantation, Homologous / Q000276:immunology*; D000813:Anilides; D001549:Benzamides; D011743:Pyrimidines
D016572:Cyclosporine; D007166:Immunosuppressive Agents; D007519:Isoantigens; D016328:NF-kappa B; D009930:Organic Chemicals; D018808:Transcription Factor AP-1; C102914:N-(3,5-bis(trifluoromethyl)phenyl)-2-chloro-4-(trifluoromethyl)pyrimidine-5-carboxamide; D000813:Anilides; D001549:Benzamides; D011743:Pyrimidines