[Pseudoxanthoma elasticum: a rare cause of leg artery diseases in young adults].
Pseudoxanthoma elasticum (PXE) is a rare inherited connective tissue disorder which is characterized by elastic tissue degeneration involving the skin, eyes and arteries. We describe the case of a hypercholesterolemic 25 year-old woman with typical genetic dominant form of PXE revealed by distal limb artery involvement after a pregnancy. In young adults with arterial disease, a non atheromatous cause should always be sought for, even if risk factors for atherosclerosis are present.
Cailleux
N
N
Service de Médecine interne, CHU, Hôpital Claude Huriez, Lille.
Hachulla
E
E
Perez-Cousin
M
M
Labalette
P
P
Lecomte-Houcke
M
M
D000328:Adult; D001158:Arteries; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications; D007866:Leg / Q000098:blood supply*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000209:etiology*; D011561:Pseudoxanthoma Elasticum / Q000150:complications / Q000235:genetics*; D012307:Risk Factors