title: Genital herpes in a primary care clinic. Demographic and sexual correlates of herpes simplex type 2 infections.
abstract: OBJECTIVE
  Genital herpes remains one of the most prevalent sexually transmitted diseases (STDs). The sexual behavioral correlates of herpes simplex virus type 2 (HSV-2) infection in the general population have not been well characterized.
  
  
  OBJECTIVE
  To assess demographic and sexual behavioral correlates of symptomatic and subclinical HSV-2 infection.
  
  
  METHODS
  Cross-sectional survey of 922 randomly chosen patients and 78 of their partners (1,000 total) in a family practice. Sexual behavior information was collected in 492 people.
  
  
  RESULTS
  Two hundred twenty-five (23%) heterosexual people had HSV-2 infection, but only 59 (26%) reported a history of genital herpes. HSV-2 seroprevalence was 63% in African-American women, 27% in white women, 40% in African-American men, and 12% in white men. In multivariate analyses of risk factors for HSV-2 infection among men, 10 or more sexual partners and a prior STD were statistically significantly associated with HSV-2 infection. Among white women, number of sexual partners, a prior STD, marriage or cohabitation, and less than a college education were predictive of HSV-2 infection. A history of oral sex was the only statistically significant predictor of HSV-2 infection in African-American women.
  
  
  CONCLUSIONS
  Risk factors for HSV-2 infection differ by gender and ethnic group. Traditionally recognized behavioral correlates of STD acquisition may not identify people in communities with high prevalence of HSV-2 infection.
authors.affiliation: Department of Medicine, School of Medicine, University of Washington, Seattle 98144, USA.
authors.forename: A
authors.initials: A
authors.lastname: Wald
authors.forename: L
authors.initials: L
authors.lastname: Koutsky
authors.forename: R L
authors.initials: RL
authors.lastname: Ashley
authors.forename: L
authors.initials: L
authors.lastname: Corey
mesh_terms: D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D003430:Cross-Sectional Studies; D005260:Female; D006558:Herpes Genitalis / Q000453:epidemiology*; D006561:Herpes Simplex / Q000453:epidemiology; D018258:Herpesvirus 2, Human / Q000276:immunology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012725:Sexual Behavior
chemical_list: D000914:Antibodies, Viral