Clinical and radiologic findings in progressive facial hemiatrophy (Parry-Romberg syndrome).
We describe the clinical and radiologic changes related to progressive facial hemiatrophy (Parry-Romberg syndrome) occurring during a 20-month period in a child who presented with unilateral neurologic deficits and facial hemiatrophy. CT and MR findings included unilateral focal infarctions in the corpus callosum, diffuse deep and subcortical white matter signal changes, mild cortical thickening, and leptomeningeal enhancement with dense mineral deposition. Angiographic findings were normal. We hypothesize that a noninfectious, unilateral inflammatory process, possibly associated with a chronic vasomotor disturbance and sympathetic nerve chain inflammation, was a major factor in the pathogenesis of this syndrome.
Cory
R C
RC
Department of Radiology, University of Florida Health Science Center/Jacksonville 32209, USA.
Clayman
D A
DA
Faillace
W J
WJ
McKee
S W
SW
Gama
C H
CH
D001099:Arachnoid / Q000473:pathology; D001342:Autonomic Nervous System Diseases / Q000150:complications; D001927:Brain Diseases / Q000175:diagnosis / Q000473:pathology*; D002114:Calcinosis / Q000175:diagnosis; D002533:Cerebral Angiography; D002544:Cerebral Infarction / Q000175:diagnosis; D002675:Child, Preschool; D003337:Corpus Callosum / Q000473:pathology; D003952:Diagnostic Imaging; D018450:Disease Progression; D005150:Facial Hemiatrophy / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008903:Minerals; D010841:Pia Mater / Q000473:pathology; D013564:Sympathetic Nervous System / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014666:Vasomotor System / Q000473:pathology
D008903:Minerals