Lactoferrin in tears in contact lens wearers.
OBJECTIVE
The purpose of this study was to examine the concentration of lactoferrin in 126 healthy subjects before being fitted with contact lenses. We obtained repeat measurements 9 months following contact lens fitting in patients who developed giant papillary conjunctivitis and in those who were successful contact lens wearers.


METHODS
We accomplished tear stimulation by the use of Allyl sulphide, a non-toxic organic compound. We measured lactoferrin by the radial immuno-diffusion technique.


RESULTS
We found a significant decrease of lactoferrin levels in the tears of patients with giant papillary conjunctivitis.
Velasco Cabrera
M J
MJ
Department of Optics, Science Faculty, University of Granada, Spain.
García Sánchez
J
J
Bermúdez Rodríguez
F J
FJ
D000293:Adolescent; D000328:Adult; D015415:Biomarkers; D003233:Conjunctivitis, Allergic / Q000209:etiology / Q000378:metabolism; D003261:Contact Lenses / Q000009:adverse effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007781:Lactoferrin / Q000378:metabolism*; D008297:Male; D012016:Reference Values; D013666:Tears / Q000187:drug effects / Q000378:metabolism*; D013997:Time Factors
D015415:Biomarkers; D007781:Lactoferrin