title: Human cortical plasticity: functional recovery with mirror movements.
abstract: Cortical plasticity of the human brain permits functional recovery after brain injury even in the absence of neuronal recovery. We report the combined evaluation, including electrophysiology and functional magnetic resonance imaging, of the pattern of cortical and cerebellar reorganization, in a patient with mirror movements as a sequel of perinatal unilateral brain injury. Recovery resulted in motor control by the healthy hemisphere using direct ipsilateral corticospinal projections and the contralateral cerebellum.
authors.affiliation: Department of Neurology, University Hospital, Bern, Switzerland.
authors.forename: A C
authors.initials: AC
authors.lastname: Nirkko
authors.forename: K M
authors.initials: KM
authors.lastname: Rösler
authors.forename: C
authors.initials: C
authors.lastname: Ozdoba
authors.forename: O
authors.initials: O
authors.lastname: Heid
authors.forename: G
authors.initials: G
authors.lastname: Schroth
authors.forename: C W
authors.initials: CW
authors.lastname: Hess
mesh_terms: D000293:Adolescent; D002540:Cerebral Cortex / Q000503:physiopathology*; D004558:Electric Stimulation; D004594:Electrophysiology; D005121:Extremities / Q000503:physiopathology; D005260:Female; D006429:Hemiplegia / Q000503:physiopathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008280:Magnetics; D009068:Movement / Q000502:physiology*; D009128:Muscle Spasticity / Q000503:physiopathology*; D009473:Neuronal Plasticity