Chorda tympani nerve transection disrupts taste aversion learning to potassium chloride, but not sodium chloride.
In Experiment 1, rats with chorda tympani nerve transection (CTX) acquired a LiCl-conditioned taste aversion to 0.1 M NaCl at the same rate as controls. After 3 conditioning trials, the aversion generalized to 0.03 and 0.3 M NaCl, but did not generalize to KCI (0.03, 0.1, and 0.3 M), in either the sham or CTX group. In Experiment 2, the sham group, but not the CTX group, formed an aversion to 0.1 M KCI after 1 trial. The CTX rats did form a moderate aversion after 2 conditioning trials. Following the 3rd trial, the CTX group did not suppress licking to 0.03 or 0.3 M KCI or any concentration of NaCl in relation to controls. Although there is strong evidence that CTX affects NaCl taste perception, these findings indicate that, under certain conditions, rats can nonetheless distinguish NaCl from KCI after such neurotomy. Moreover, CTX appears to have a substantial effect on the perceived intensity of KCl.
St John
S J
SJ
Department of Psychology, University of Florida, Gainesville 32611-2250, USA.
Markison
S
S
Spector
A C
AC
D000818:Animals; D001362:Avoidance Learning / Q000502:physiology*; D001931:Brain Mapping; D002814:Chorda Tympani Nerve / Q000502:physiology*; D004193:Discrimination Learning / Q000502:physiology*; D005795:Generalization, Stimulus / Q000502:physiology; D008297:Male; D011939:Mental Recall / Q000502:physiology*; D011189:Potassium Chloride / Q000008:administration & dosage; D051381:Rats; D017207:Rats, Sprague-Dawley; D012462:Saline Solution, Hypertonic / Q000008:administration & dosage; D013649:Taste / Q000502:physiology*; D013650:Taste Buds / Q000502:physiology; D013652:Taste Threshold / Q000502:physiology
D012462:Saline Solution, Hypertonic; D011189:Potassium Chloride