title: Changes of presaccadic cortical activity when performing horizontal, visually guided saccades.
abstract: When a visually guided saccade task is running, the presaccadic potential obtained in the initial period of the task differs from those obtained later, while the subject's oculomotor performance remains unaffected. These time-related changes of cortical activity consist both of an overall decreasing electrical activity as well as a selective one over certain cortical areas. The generalised reduced activity already described in earlier studies is considered as an unspecified effect such as fatigue or decreased motivation. On the contrary, the pronounced selective changes of cortical activity obtained over cortical areas such as the centro-parietal and frontal cortices, should be related with more specific, that is, visuomotor function. We assume that at the beginning of the task of the performance of the saccade needs the activation of several cortical areas but later on the same oculomotor plan runs sufficiently under subcortical control.
authors.affiliation: ENG Laboratory, Neurological Clinic, Athens University, Greece.
authors.forename: I
authors.initials: I
authors.lastname: Evdokimidis
authors.forename: T S
authors.initials: TS
authors.lastname: Constantinidis
authors.forename: P
authors.initials: P
authors.lastname: Gourtzelidis
authors.forename: D
authors.initials: D
authors.lastname: Liakopoulos
authors.forename: C
authors.initials: C
authors.lastname: Papageorgiou
mesh_terms: D000328:Adult; D002540:Cerebral Cortex / Q000502:physiology*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D010775:Photic Stimulation; D012438:Saccades / Q000502:physiology*; D013647:Task Performance and Analysis