title: Primary amenorrhea: evaluation with MR imaging.
abstract: OBJECTIVE
  To determine the accuracy of magnetic resonance (MR) imaging in the evaluation of patients with a history of primary amenorrhea.
  
  
  METHODS
  Twenty-nine patients with primary amenorrhea underwent T2-weighted MR imaging in the axial and sagittal planes. Contrast material-enhanced and unenhanced T1-weighted MR imaging was performed in selected cases. MR imaging findings were correlated with surgical findings in 23 patients and with clinical findings in six patients.
  
  
  RESULTS
  Surgical correlation was available in 14 of 17 patients with female anatomic anomalies (Mayer-Rokitansky-Küster-Hauser syndrome [n = 9], transverse vaginal septum [n = 3], imperforate hymen [n = 1], cervical agenesis [n = 1]), which confirmed MR imaging findings. In nine of 12 patients with congenital disorders of sexual differentiation (testicular feminization [n = 5], true hermaphrodite [n = 2], gonadal dysgenesis [n = 2]) who underwent surgical correlation, 13 of 16 (81%) gonads were correctly localized with MR imaging. Overall, there was excellent correlation between the classification of patients with MR imaging versus classification with the combination of surgical and laboratory findings (K = 0.88).
  
  
  CONCLUSIONS
  MR imaging is useful in the work-up of patients who present with primary amenorrhea both for accurate diagnosis of pathologic conditions and for surgical planning.
authors.affiliation: Department of Diagnostic Radiology, Montreal General Hospital, Quebec, Canada.
authors.forename: C
authors.initials: C
authors.lastname: Reinhold
authors.forename: H
authors.initials: H
authors.lastname: Hricak
authors.forename: R
authors.initials: R
authors.lastname: Forstner
authors.forename: S M
authors.initials: SM
authors.lastname: Ascher
authors.forename: P M
authors.initials: PM
authors.lastname: Bret
authors.forename: W R
authors.initials: WR
authors.lastname: Meyer
authors.forename: R C
authors.initials: RC
authors.lastname: Semelka
mesh_terms: D000293:Adolescent; D000328:Adult; D000568:Amenorrhea / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery; D002584:Cervix Uteri / Q000002:abnormalities; D002648:Child; D012734:Disorders of Sex Development / Q000175:diagnosis; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D014621:Vagina / Q000002:abnormalities