title: [Study by NMR of the modifications of brain lipid composition related to the tumor processes].
abstract: 1H, 13C, 31P and 14N NMR spectroscopies were used to investigate the lipid composition of brain tumors (GL6 glioma) in rats, by comparison with controlateral hemispheres. Comparative indexes derived from NMR signal intensities were used to establish the statistical analysis. It was found that sterol metabolism and sphingolipid/glycerolipids ratio are significantly modified when a tumor is present.
authors.affiliation: CRSSA, Service de Biophysique, La Tronche.
authors.forename: J C
authors.initials: JC
authors.lastname: Debouzy
authors.forename: F
authors.initials: F
authors.lastname: Fauvelle
authors.forename: N
authors.initials: N
authors.lastname: Fouilhe
authors.forename: E
authors.initials: E
authors.lastname: Sam-Lai
authors.forename: C
authors.initials: C
authors.lastname: Nemoz
authors.forename: L
authors.initials: L
authors.lastname: Girault
authors.forename: L
authors.initials: L
authors.lastname: Mazet
mesh_terms: D000818:Animals; D001923:Brain Chemistry; D001932:Brain Neoplasms / Q000737:chemistry*; D005910:Glioma / Q000737:chemistry*; D008055:Lipids / Q000032:analysis*; D009682:Magnetic Resonance Spectroscopy; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D008055:Lipids