Preliminary clinical experience with the first dual chamber pacemaker defibrillator.
The lack of specificity of VT detection is a significant shortcoming of current ICDs. In a French multicenter study, 18 patients underwent implantation of the Defender 9001 (ELA Medical), an ICD utilizing dual chamber pacing and arrhythmia detection. Over a mean follow-up period of 7.1 +/- 4.5 months, 176 tachycardia episodes recorded in the device memory were analyzed, and physician diagnosis was compared with that by the device. All 122 VT/VF episodes were correctly diagnosed, as were 51 of 53 supraventricular tachyarrhythmias. Two episodes of AF with rapid regular ventricular rates were treated as VT, and a third episode, treated as VT, could not be diagnosed with certainty. A dual chamber pacemaker defibrillator offers improved diagnostic specificity without loss of sensitivity, in addition to the hemodynamic benefit of dual chamber pacing.
Lavergne
T
T
Hôpital Broussais, Paris, France.
Daubert
J C
JC
Chauvin
M
M
Dolla
E
E
Kacet
S
S
Leenhardt
A
A
Mabo
P
P
Ritter
P
P
Sadoul
N
N
Saoudi
N
N
Henry
C
C
Nitzsche
R
R
Ripart
A
A
Murgatroyd
F
F
D000293:Adolescent; D000328:Adult; D000368:Aged; D000465:Algorithms; D001145:Arrhythmias, Cardiac / Q000175:diagnosis / Q000628:therapy; D001281:Atrial Fibrillation / Q000175:diagnosis / Q000628:therapy; D002304:Cardiac Pacing, Artificial; D017147:Defibrillators, Implantable; D004867:Equipment Design; D005080:Exercise Test; D005260:Female; D005500:Follow-Up Studies; D005602:France; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial; D010820:Physicians; D012680:Sensitivity and Specificity; D013610:Tachycardia / Q000175:diagnosis; D013617:Tachycardia, Supraventricular / Q000175:diagnosis / Q000628:therapy; D017180:Tachycardia, Ventricular / Q000175:diagnosis; D014693:Ventricular Fibrillation / Q000175:diagnosis / Q000628:therapy