title: Do aminoglycoside otic preparations cause ototoxicity in the presence of tympanic membrane perforations?
authors.affiliation: Department of Otolaryngology, University of Toronto, Ontario, Canada.
authors.forename: D L
authors.initials: DL
authors.lastname: Wong
authors.forename: J A
authors.initials: JA
authors.lastname: Rutka
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D007758:Ear, Inner / Q000187:drug effects*; D005260:Female; D005839:Gentamicins / Q000009:adverse effects*; D006319:Hearing Loss, Sensorineural / Q000139:chemically induced; D006801:Humans; D008297:Male; D008875:Middle Aged; D010033:Otitis Media / Q000150:complications / Q000188:drug therapy; D004856:Postural Balance; D018058:Tympanic Membrane Perforation / Q000150:complications; D014717:Vertigo / Q000139:chemically induced; D015837:Vestibular Diseases / Q000139:chemically induced
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins