title: A cross-sectional study comparing two quantitative sensory testing devices in individuals with diabetes.
abstract: OBJECTIVE
  This study was designed to compare circumference discrimination thresholds, as assessed by the Tacticon (Tacticon, Inc., Westtown, PA), a new quantitative sensory testing (QST) device, with vibratory thresholds, an assessment modality of large sensory nerve fibers, in individuals with diabetes.
  
  
  METHODS
  In this study, 150 individuals with diabetes were evaluated. Vibratory thresholds and circumference discrimination thresholds, evaluated with the Tacticon, were determined using a two-alternative forced-choice procedure.
  
  
  RESULTS
  Vibratory thresholds increased with decreasing ability to discriminate differences in circumference (P < 0.001) for those below and above 50 years of age. Agreement between the two QST devices was assessed via the kappa-statistic in both age-groups (i.e., < or = 50 years old [kappa = 0.67], > 50 years old [kappa = 0.55]). In multiple logistic regression, where circumference discrimination thresholds were the dependent variable, age, duration of diabetes, and height were found to be independently associated for those > 50 years old.
  
  
  CONCLUSIONS
  The Tacticon offers a simple method of assessing the complex function of area discrimination. Our results suggest that the Tacticon can detect neuropathy in the primary care setting. Its cost, portability, and ease of use provide some advantages over existing QST equipment.
authors.affiliation: University of Delaware, Newark 19716, USA. 26338@brahms.udel.edu
authors.forename: R E
authors.initials: RE
authors.lastname: Maser
authors.forename: C
authors.initials: C
authors.lastname: Laudadio
authors.forename: M J
authors.initials: MJ
authors.lastname: Lenhard
authors.forename: G S
authors.initials: GS
authors.lastname: DeCherney
mesh_terms: D000328:Adult; D000368:Aged; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D003929:Diabetic Neuropathies / Q000145:classification / Q000175:diagnosis*; D004864:Equipment and Supplies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D012684:Sensory Thresholds / Q000502:physiology*; D014732:Vibration