Successful down-regulation of natural and xenoreactive antibodies in pig-to-baboon xenotransplantation by high-dose cyclophosphamide.
Morschheuser
T
T
Department of Cardiovascular Surgery, University of Kiel, Germany.
Steinhoff
G
G
Indzhiia
L
L
Heiser
A
A
Hein
M
M
Lapin
B A
BA
Haverich
A
A
D000818:Animals; D000910:Antibodies, Heterophile / Q000096:biosynthesis* / Q000097:blood; D000917:Antibody Formation / Q000187:drug effects; D001011:Aorta; D017690:Cell Transplantation; D002478:Cells, Cultured; D003520:Cyclophosphamide / Q000494:pharmacology*; D004730:Endothelium, Vascular / Q000166:cytology / Q000637:transplantation*; D007074:Immunoglobulin G / Q000096:biosynthesis* / Q000097:blood; D007075:Immunoglobulin M / Q000096:biosynthesis* / Q000097:blood; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D010215:Papio; D013552:Swine; D013997:Time Factors; D014183:Transplantation, Heterologous / Q000276:immunology*
D000910:Antibodies, Heterophile; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide