title: Reactive airways dysfunction syndrome: occurrence after exposure to a refractory ceramic fiber-phosphoric acid binder mixture.
abstract: A previously healthy, 47-year-old millwright was exposed to high airborne levels of a refractory ceramic fiber-phosphoric acid binder mixture; after acute bronchospasm, he required hospitalization. During the next 4 years, he had recurrent acute bronchospasm requiring emergency department visits and three hospitalizations. Review of the patient's medical and occupational history and extensive clinical investigation failed to provide alternate explanations for this hyperresponsive airways disease. This is believed to be the first reported case of reactive airways dysfunction syndrome (RADS) after exposure to a refractory ceramic fiber-phosphoric acid binder mixture. Physicians should be aware of this possibility when examining patients exposed to such materials.
authors.affiliation: Department of Family and Community Medicine, University of Alabama School of Medicine, University of Alabama at Birmingham 35294-2042, USA.
authors.forename: B G
authors.initials: BG
authors.lastname: Forrester
mesh_terms: D016535:Bronchial Hyperreactivity / Q000139:chemically induced* / Q000503:physiopathology; D002516:Ceramics / Q000009:adverse effects*; D006801:Humans; D008176:Lung Volume Measurements; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000139:chemically induced*; D016273:Occupational Exposure / Q000009:adverse effects*; D010756:Phosphoric Acids / Q000009:adverse effects*; D012130:Respiratory Hypersensitivity / Q000139:chemically induced; D013577:Syndrome
chemical_list: D010756:Phosphoric Acids; C030242:phosphoric acid