Structure and expression of the mouse S10 gene.
We previously reported the cloning of a human S10 cDNA which encodes a small GTP-binding protein belonging to the Rab subfamily. Here we describe a mouse S10 cDNA and its genomic structure. Mouse S10 is 92.3% homologous at the nucleotide level and 98.3% identical at the amino acid level compared to human S10. The mouse S10 gene is comprised of two exons and a single intron. Northern blotting of tissue RNAs indicates that the S10 gene is predominantly expressed in brain.
Zheng
J Y
JY
Institute of Immunological Science, Hokkaido University, Sapporo, Japan.
Koda
T
T
Arimura
Y
Y
Kishi
M
M
Kakinuma
M
M
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000235:genetics; D005091:Exons; D019204:GTP-Binding Proteins / Q000235:genetics*; D015698:Genomic Library; D007438:Introns; D051379:Mice; D008969:Molecular Sequence Data; D012333:RNA, Messenger / Q000235:genetics; D017386:Sequence Homology, Amino Acid; D014018:Tissue Distribution; D020691:rab GTP-Binding Proteins
D018076:DNA, Complementary; D012333:RNA, Messenger; C484540:Rab33a protein, mouse; D019204:GTP-Binding Proteins; D020691:rab GTP-Binding Proteins