Chloride absorption in patients with a continent ileocaecal reservoir (Mainz pouch I).
OBJECTIVE
To determine the rate of radioactive chloride absorption at various times after surgery in patients with a continent ileocaecal reservoir (Mainz pouch I).


METHODS
The study was conducted on 20 patients (15 males and five females, mean age 47 years, range 15-72) who had undergone a Mainz pouch I urinary diversion. The patients were divided into three groups according to the duration of the post-operative follow-up, i.e. group 1 for < 6 months (n = 7), group 2 for 6-12 months (n = 8) and group 3 for > 12 months (n = 5). Radioactive 38Cl (20 MBq) was instilled into the pouch and the radioactivity determined in the blood, pouch and body interstitium every 20 min for 3 h. Samples for arterial blood-gas and acid-base profiles were obtained before and after instillation.


RESULTS
In patients in group 1, 93% of the instilled chloride was absorbed into the circulation, while 51% was absorbed by patients in group 3. The acid-base profile showed no significant changes before and after chloride instillation.


CONCLUSIONS
The absorption of chloride declines markedly with time after surgery in patients with a Mainz pouch I ileocaecal reservoir.
Filipas
D
D
Department of Urology, University of Mainz, School of Medicine, Germany.
Fisch
M
M
Abol Enein
H
H
Fichtner
J
J
Bockisch
A
A
Hohenfellner
R
R
D000042:Absorption; D000136:Acid-Base Equilibrium; D000138:Acidosis / Q000378:metabolism; D000293:Adolescent; D000328:Adult; D000368:Aged; D002712:Chlorides / Q000097:blood / Q000378:metabolism*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016476:Urinary Reservoirs, Continent
D002712:Chlorides