Progress in standardization of immunoassays for prostate-specific antigen.
A calibrator composed of 90% prostate-specific antigen-alpha 1-antichymotrypsin (PSA-ACT) and 10% free PSA reduces the variation in control serums with widely divergent amounts of free PSA, from a mean of 28% among nine different assays to 9% after recalibration. The lyophilized form of the Stanford 90:10 calibrator is stable and therefore an excellent candidate for international standardization of PSA assays.
Stamey
T A
TA
Department of Urology, Stanford University Medical Center, California, USA.
D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D007118:Immunoassay / Q000592:standards*; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000175:diagnosis
D017430:Prostate-Specific Antigen