Bone densitometry of proximal femur in Chinese subjects: gender differences in bone mass and bone areas.
Bone mineral content (BMC), bone areas (BA), and bone mineral density (BMD) of the proximal femur were measured in 202 healthy Chinese men and 507 healthy Chinese women, aged 21-70 years, to investigate gender differences in densitometry of the femur. Densitometric values measured at the femoral neck, trochanter, and Ward's triangle were generally greater in men than women of the same age, except at Ward's triangle. While BMD decreased with aging with similar slopes of -0.2 approximately -1% per year, the actual readings were 10%-15% lower than those of Caucasian subjects of the same age and gender for Chinese men and women. Furthermore, with increasing age, trochanteric BA increased in women but not in men, and femoral neck BA increased in men but not in women. These different trends of change in bone dimensions were independent of weight or height. They may reflect a structural difference at the proximal femur and imply differences in mechanical strength, and thus may have played some roles in the different incidence of hip fractures between the elderly men and women.
Tsai
K S
KS
Department of Laboratory Medicine, College of Medicine, National Taiwan University, Taipei, Republic of China.
Cheng
W C
WC
Sanchez
T V
TV
Chen
C K
CK
Chieng
P U
PU
Yang
R S
RS
D015502:Absorptiometry, Photon; D000328:Adult; D000368:Aged; D000375:Aging / Q000473:pathology; D000704:Analysis of Variance; D044466:Asian People; D015519:Bone Density / Q000502:physiology*; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging / Q000502:physiology; D006801:Humans; D008297:Male; D008593:Menopause; D008875:Middle Aged; D010024:Osteoporosis / Q000503:physiopathology*; D015663:Osteoporosis, Postmenopausal / Q000503:physiopathology*; D017697:Premenopause; D015203:Reproducibility of Results; D012727:Sex Characteristics; D013624:Taiwan