title: Assessment of diurnal tensional curve in early glaucoma damage.
abstract: We know very little about the relationship between the diurnal intraocular pressure variations and the progression of visual field loss. A prospective study of 149 eyes of 149 patients suffering from intraocular hypertension has been carried out through a minimum period of five years. At least 4 years before the appearance of field defects, we detected significant oscillations of IOP in the 64% of the cases prone to develop visual field loss. Likewise, we have found a statistically significant relationship between the presence of defects in the RNFL (retinal nerve fiber layer) and the existence of significant oscillations of IOP.
authors.affiliation: Department of Ophthalmology, Miguel Servet Hospital, Zaragoza, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Gonzalez
authors.forename: L E
authors.initials: LE
authors.lastname: Pablo
authors.forename: M
authors.initials: M
authors.lastname: Pueyo
authors.forename: E
authors.initials: E
authors.lastname: Ferrer
authors.forename: B
authors.initials: B
authors.lastname: Melcon
authors.forename: E
authors.initials: E
authors.lastname: Abecia
authors.forename: F M
authors.initials: FM
authors.lastname: Honrubia
mesh_terms: D002940:Circadian Rhythm / Q000502:physiology*; D018450:Disease Progression; D005500:Follow-Up Studies; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D009798:Ocular Hypertension / Q000150:complications / Q000503:physiopathology*; D009900:Optic Nerve / Q000473:pathology; D011446:Prospective Studies; D014065:Tonometry, Ocular; D014794:Visual Fields