title: Trinucleotide repetition and fragile X syndrome.
abstract: Insufficiently appreciated as a cause of learning disability and other behavioral problems, fragile X syndrome accounts for almost 10% of inherited mental retardation. Identification of the specific mutation as a dramatic trinucleotide expansion inaugurates an era of accurate diagnosis, and goes far toward explaining the syndrome's inheritance patterns, in which risk varies as the disease descends through a family.
authors.affiliation: Emory University School of Medicine, Atlanta, USA.
authors.forename: S T
authors.initials: ST
authors.lastname: Warren
mesh_terms: D000595:Amino Acid Sequence; D005260:Female; D005600:Fragile X Syndrome / Q000235:genetics*; D005838:Genotype; D006801:Humans; D008297:Male; D008967:Molecular Biology; D010375:Pedigree; D010641:Phenotype; D012737:Sex Factors; D018911:Trinucleotide Repeats / Q000235:genetics*