Distribution of melanin-concentrating hormone (MCH)-like immunoreactivity in neurons of the diencephalon of sheep.
An immunohistochemical study with an antiserum raised against salmon melanin concentrating-hormone has demonstrated the presence of numerous melanin concentrating-hormone-immunoreactive neurons in the lateral hypothalamic areas of the sheep. The pattern of distribution of these perikarya is similar to that of rodents and primates. In sheep, however, melanin concentrating-hormone-immunoreactive neurons appeared to form two gatherings: the first is situated ventromedially to the internal capsule and the second in the dorsolateral hypothalamus. In these areas, numerous immunostained perikarya are observed. Compared to the rats, labelled neurons extended more caudally in the ventral tegmental area and more rostrally above the optic chiasma. Compared to primates, these neurons are less numerous in the periventricular area. In our study, dense networks of melanin concentrating-hormone-immunoreactive varicose fibers were observed in the supramamillary nucleus, the lateral hypothalamus, the nucleus medialis thalami and nucleus reuniens and in the bed nucleus of the stria terminalis.
Tillet
Y
Y
Unité de Neuroendocrinologie Sexuelle, INRA Station de Physiologie de la Reproduction des Mammifères Domestiques, Nouzilly, France.
Batailler
M
M
Fellmann
D
D
D000818:Animals; D004027:Diencephalon / Q000033:anatomy & histology / Q000737:chemistry*; D005260:Female; D007028:Hypothalamic Hormones / Q000032:analysis*; D007031:Hypothalamus / Q000033:anatomy & histology / Q000737:chemistry; D007150:Immunohistochemistry; D008297:Male; D008543:Melanins / Q000032:analysis*; D009474:Neurons / Q000737:chemistry*; D010907:Pituitary Hormones / Q000032:analysis*; D012756:Sheep
D007028:Hypothalamic Hormones; D008543:Melanins; D010907:Pituitary Hormones; C019463:melanin-concentrating hormone