title: Apoprotein B in subretinal fluid.
abstract: We studied the presence of apolipoprotein B (apo B) by immunoelectrophoresis in subretinal fluid (SRF) and serum from 15 rhegmatogenous retinal detachments and 5 retinal detachments with proliferative vitreoretinopathy (PVR). Apo B concentration +/- standard deviation was 1.49 +/- 1.06 mg/dl in SRF and 108.41 +/- 40.22 mg/dl in serum. Only in four cases was apo B not detected in SRF. We found no significant correlation between apo B concentrations in SRF and apo B levels in serum. We did not find a positive correlation between apo B concentrations in SRF and the duration and size of the detachments. There was no statistical relationship between the presence of PVR and apo B levels. This phenomenon suggests the preservation of the outer blood retinal barrier during rhegmatogenous retinal detachment.
authors.affiliation: Department of Ophthalmology, University Clinic Hospital, Zaragoza, Spain.
authors.forename: V
authors.initials: V
authors.lastname: Huerva
authors.forename: B
authors.initials: B
authors.lastname: Sinués
authors.forename: L M
authors.initials: LM
authors.lastname: Canto
authors.forename: J
authors.initials: J
authors.lastname: Lanuza
authors.forename: A
authors.initials: A
authors.lastname: Palomar
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001055:Apolipoproteins B / Q000032:analysis* / Q000097:blood; D001813:Blood-Retinal Barrier / Q000502:physiology; D001826:Body Fluids / Q000737:chemistry*; D005122:Exudates and Transudates / Q000737:chemistry; D005260:Female; D006801:Humans; D007122:Immunoelectrophoresis / Q000379:methods; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000209:etiology / Q000378:metabolism; D012680:Sensitivity and Specificity; D018630:Vitreoretinopathy, Proliferative / Q000150:complications / Q000378:metabolism
chemical_list: D001055:Apolipoproteins B