title: [Long-term follow-up study of children with minimal change nephrotic syndrome].
abstract: We conducted a long-term follow-up study of 37 children with biopsy-proved minimal change nephrotic syndrome during a period of over 6 years from onset to adulthood. These patients were classified into 4 groups of 13 infrequent relapsers, 17 frequent relapsers, 3 non-responders and 4 no-relapsers according to the International Study of Kidney Disease in Children (ISKDC). All patients were treated with conventional prednisolone therapy. Two cases of infrequent relapsers, 7 cases of frequent relapsers and 1 case of non responders relapsed in adult life. Two cases of infrequent relapsers and 1 case of frequent relapsers relapsed in adult life after remission for 5 or more years. We concluded that minimal change nephrotic syndromes in childhood should be followed up over a long duration in adult life, evenly in cases with good steroid responsiveness.
authors.affiliation: Department of Pediatrics, Fujita Health University School of Medicine, Aichi, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Takeichi
authors.forename: M
authors.initials: M
authors.lastname: Tazawa
authors.forename: M
authors.initials: M
authors.lastname: Morooka
authors.forename: S
authors.initials: S
authors.lastname: Minowa
authors.forename: T
authors.initials: T
authors.lastname: Yasaki
mesh_terms: D002648:Child; D005500:Follow-Up Studies; D006801:Humans; D009402:Nephrosis, Lipoid / Q000188:drug therapy*; D011239:Prednisolone / Q000627:therapeutic use*; D011379:Prognosis; D012008:Recurrence; D012074:Remission Induction
chemical_list: D011239:Prednisolone