Intracellular staining of angiotensin receptors in the PVN and SON of the rat.
Our immunocytochemical results demonstrate the presence of angiotensin AT1 receptors in the cytoplasm and at the cell membrane in paraventricular and supraoptic neurons of the rat hypothalamus. The reaction product had a punctate appearance. We found no staining in the cell nucleus. Similar results were obtained with an anti-idiotypic antibody to angiotensin II.
Pfister
J
J
Division of Neurobiology, University of Berne, Switzerland.
Spengler
C
C
Grouzmann
E
E
Raizada
M K
MK
Felix
D
D
Imboden
H
H
D000818:Animals; D002462:Cell Membrane / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D006652:Histological Techniques / Q000295:instrumentation; D007150:Immunohistochemistry; D008297:Male; D009474:Neurons / Q000166:cytology*; D010286:Paraventricular Hypothalamic Nucleus / Q000166:cytology*; D051381:Rats; D011921:Rats, Inbred WKY; D044140:Receptor, Angiotensin, Type 1; D044139:Receptor, Angiotensin, Type 2; D011945:Receptors, Angiotensin / Q000032:analysis*; D013495:Supraoptic Nucleus / Q000166:cytology*
D044140:Receptor, Angiotensin, Type 1; D044139:Receptor, Angiotensin, Type 2; D011945:Receptors, Angiotensin