title: Comparison of fallopian tube sperm perfusion with intrauterine insemination in the treatment of infertility.
abstract: OBJECTIVE
  To compare the efficacy of fallopian tube sperm perfusion utilizing a Foley catheter technique with standard IUI.
  
  
  METHODS
  Randomized controlled study.
  
  
  METHODS
  The infertility units of the University Central Hospital and the Family Federation of Finland, Oulu, Finland.
  
  
  METHODS
  One hundred infertile women with unexplained factor, minimal to mild endometriosis, mild male factor, or ovarian dysfunction, undergoing 50 IUI and 50 fallopian tube sperm perfusion cycles stimulated by clomiphene citrate and hMG.
  
  
  METHODS
  Thirty-six hours after hCG administration, patients were randomized to either the IUI group (group 1, 50 patients and cycles) or the fallopian tube sperm perfusion group (group 2, 50 patients and cycles). Intrauterine insemination was performed using a standard method and fallopian tube sperm perfusion with a pediatric Foley catheter, which prevents the reflux of sperm suspension.
  
  
  METHODS
  Number of clinical pregnancies.
  
  
  RESULTS
  The fallopian tube sperm perfusion method using a Foley catheter technique was easy to perform and convenient for the patients. The overall pregnancy rate per cycle was 8% for fallopian tube sperm perfusion and 20% for IUI, a difference that was not significant.
  
  
  CONCLUSIONS
  The fallopian tube sperm perfusion method using a Foley catheter offers no advantage in comparison with the conventional IUI technique.
authors.affiliation: Department of Obstetrics and Gynecology, Oulu University Hospital, Finland.
authors.forename: S
authors.initials: S
authors.lastname: Nuojua-Huttunen
authors.forename: L
authors.initials: L
authors.lastname: Tuomivaara
authors.forename: K
authors.initials: K
authors.lastname: Juntunen
authors.forename: C
authors.initials: C
authors.lastname: Tomás
authors.forename: H
authors.initials: H
authors.lastname: Martikainen
mesh_terms: D000328:Adult; D002996:Clomiphene / Q000627:therapeutic use; D005187:Fallopian Tubes; D005260:Female; D006801:Humans; D007246:Infertility / Q000628:therapy*; D007317:Insemination, Artificial, Homologous / Q000379:methods*; D008297:Male; D008596:Menotropins / Q000627:therapeutic use; D010477:Perfusion; D011247:Pregnancy
chemical_list: D002996:Clomiphene; D008596:Menotropins