title: [Cervical pregnancy: case report and review of the literature].
abstract: We report on a 22 years old patient with an intact cervical pregnancy located around the cervical isthmus in the 9th week of gestation. Because of the patients strong desire to maintain the reproductive capability, we performed a transvaginal amniotic sac puncture with local application of methotrexate. Later on we applied a systemic methotrexate therapy because of persistent high serum beta-hCG values. Five weeks later the patients developed heavy vaginal bleeding despite low beta-hCG levels so we are obliged to perform vaginal hysterectomy. Actual aspects about the etiology and diagnosis of this rare disease as well as about different opinions regarding conservative, fertility maintaining therapies are discussed.
authors.affiliation: Universitäts-Frauenklinik Leipzig.
authors.forename: G
authors.initials: G
authors.lastname: Pretzsch
authors.forename: J
authors.initials: J
authors.lastname: Einenkel
authors.forename: D
authors.initials: D
authors.lastname: Baier
authors.forename: L C
authors.initials: LC
authors.lastname: Horn
authors.forename: H
authors.initials: H
authors.lastname: Alexander
mesh_terms: D000328:Adult; D002584:Cervix Uteri / Q000473:pathology; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007045:Hysterectomy, Vaginal; D008727:Methotrexate / Q000008:administration & dosage; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D016216:Ultrasonography, Prenatal
chemical_list: D018997:Chorionic Gonadotropin, beta Subunit, Human; D008727:Methotrexate