title: The perinatal emphasis of Segawa's syndrome.
abstract: Segawa's syndrome is a hereditary progressive dystonia with diurnal fluctuation, which in contrast to other chronic dystonia in childhood responds dramatically to levodopa therapy. Very little is known on how it affects pregnancy or how it is affected by the pregnancy. We present a case of pregnancy of a patient, suffering from Segawa's syndrome. The patient received levodopa throughout entire two consecutive pregnancies and gave birth to two healthy male infants. The only perinatal pathology was non-progressive labor. The safety of levodopa use in pregnancy is also discussed.
authors.affiliation: Department of Obstetrics and Gynecology, Kaplan Hospital, Rehovot, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Lurie
authors.forename: V
authors.initials: V
authors.lastname: Priscu
authors.forename: Z
authors.initials: Z
authors.lastname: Hagay
mesh_terms: D000328:Adult; D004421:Dystonia / Q000150:complications* / Q000188:drug therapy; D005260:Female; D005322:Premature Rupture of Fetal Membranes; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008297:Male; D007744:Obstetric Labor Complications; D011247:Pregnancy; D011248:Pregnancy Complications; D013577:Syndrome
chemical_list: D007980:Levodopa