A clinical and histologic examination in humans of the osseous response to implanted natural bone mineral.
The purpose of this study was to assess the osseous response to implanted particles of an anorganic xenograft bone mineral. Bio-Oss, in six patients with severely resorbed alveolar ridges. The observation period varied between 9 and 44 months; in five of six patients, long-term bone regeneration around the implants was observed. Histologic examination of biopsy material obtained from the graft area showed Bio-Oss particles still present in all patients after the varying observation periods. This raises the question whether Bio-Oss may be regarded as a resorbable material, as previously reported.
Skoglund
A
A
Department of Oral and Maxillofacial Surgery, Söder Hospital, Stockholm, Sweden.
Hising
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P
Young
C
C
D000368:Aged; D000539:Alveolar Process / Q000473:pathology*; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D001672:Biocompatible Materials / Q000627:therapeutic use*; D001861:Bone Regeneration; D001862:Bone Resorption / Q000601:surgery; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D005260:Female; D005500:Follow-Up Studies; D015726:Giant Cells / Q000473:pathology; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008336:Mandibular Diseases / Q000601:surgery; D008439:Maxillary Diseases / Q000601:surgery; D008875:Middle Aged; D008903:Minerals / Q000627:therapeutic use*; D010006:Osteoblasts / Q000473:pathology; D019736:Prostheses and Implants; D014183:Transplantation, Heterologous
C077540:Bio-Oss; D001672:Biocompatible Materials; D015921:Dental Implants; D008903:Minerals