Partial synthesis of 3-O-vanilloylveracevine, an insecticidal alkaloid from Schoenocaulon officinale.
3-O-Vanilloylveracevine has been synthesized for the first time in 70% overall yield by conversion of veracevine into its 3-O-(4-benzyloxy-3-methoxybenzoate) followed by catalytic hydrogenation. The insecticidal activity of the semisynthetic substance against three pest species is inferior to that of cevadine and veratridine, the major components of the insecticidal sabadilla alkaloid mixture.
Ujváry
I
I
Plant Protection Institute, Hungarian Academy of Sciences, Budapest, Hungary.
Casida
J E
JE
D000818:Animals; D002595:Cevanes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D006793:Houseflies; D007306:Insecticides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy
C105167:3-O-vanilloylveracevine; D002595:Cevanes; D007306:Insecticides