Massive osteolysis of the skull base.
Gorham's vanishing bone disease is a rare disorder characterized by massive osteolysis. Its etiology is unknown. We report the case of a 14-year-old girl with an unusually aggressive course and extensive involvement originating within the skull base. To our knowledge this pattern has not been described previously. MR findings are discussed.
Frankel
D G
DG
Department of Diagnostic Radiology-Hb6, Cleveland Clinic Children's Hospital, OH 44195, USA.
Lewin
J S
JS
Cohen
B
B
D000293:Adolescent; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010015:Osteolysis, Essential / Q000175:diagnosis / Q000000981:diagnostic imaging; D019291:Skull Base / Q000000981:diagnostic imaging / Q000473:pathology; D014057:Tomography, X-Ray Computed