Neuropharmacological correction of cognitive processes disrupted by extirpation of the AI-AII and Ep fields in cats.
An original neuropsychophysiological battery of tests was used to study the possibility of neuropharmacological correction of compensatory-restorative processes in cats after extirpation of a defined zone of the temporal cortex; studies were carried out in conditions of free behavior. In a variety of activation and inhibition regimes, systemic administration of cholinergic, dopaminergic, GABAergic, and serotoninergic agents could have favorable effects on restorative mechanisms, depending on cortical psycho-organic symptoms. Each cognitive activity studied (perception, gnosis, thought) had its own specific positive neuromediator "profile" in terms of compensatory outcomes.
Mukhin
E I
EI
Laboratory of the Morphophysiology of Conditioned Reflexes, Science Research Institute of the Brain, Russian Academy of Medical Sciences, Moscow.
D000818:Animals; D002415:Cats; D002540:Cerebral Cortex / Q000033:anatomy & histology / Q000187:drug effects / Q000502:physiology*; D003071:Cognition / Q000187:drug effects / Q000502:physiology*; D003216:Conditioning, Operant / Q000187:drug effects / Q000502:physiology; D005260:Female; D008297:Male; D018377:Neurotransmitter Agents / Q000502:physiology; D010364:Pattern Recognition, Visual / Q000187:drug effects / Q000502:physiology; D013702:Temporal Lobe / Q000033:anatomy & histology / Q000187:drug effects / Q000502:physiology
D018377:Neurotransmitter Agents