title: [Characterization of antimicrobial properties of cefpirome].
abstract: The results of a multicentre investigation of antibiotic susceptibility in 800 clinical isolates were analyzed. The levels of susceptibility to cefpirome and other antibiotics in gram-negative organisms with inducable production of chromosomal beta-lactamases (Enterobacter, Serratia, Citrobacter and others) were compared and the advantages of cefpirome over other cephalosporins were shown: 89 per cent of the susceptible strains against 58 to 78 per cent. With respect to other microorganisms the advantages of cefpirome were less pronounced.
authors.forename: S V
authors.initials: SV
authors.lastname: Sidorenko
authors.forename: S P
authors.initials: SP
authors.lastname: Rezvan
authors.forename: A N
authors.initials: AN
authors.lastname: Makarov
authors.forename: R A
authors.initials: RA
authors.lastname: Makarova
mesh_terms: D002463:Cell Membrane Permeability / Q000187:drug effects; D002511:Cephalosporins / Q000627:therapeutic use*; D002876:Chromosomes, Bacterial; D004353:Drug Evaluation, Preclinical; D006090:Gram-Negative Bacteria / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D013210:Staphylococcus / Q000187:drug effects; D018440:beta-Lactam Resistance / Q000502:physiology; D001618:beta-Lactamases / Q000235:genetics; D000097572:Cefpirome
chemical_list: D002511:Cephalosporins; D001618:beta-Lactamases; D000097572:Cefpirome