Tolerance to a second donor-matched allograft following local immune modulation using transfer of sequences encoding CTLA4Ig.
Shaked
A
A
Department of Surgery, University of Pennsylvania, Philadelphia, USA.
Olthoff
K
K
Sellers
M
M
Chen
X D
XD
Gelman
A
A
D000069594:Abatacept; D000818:Animals; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000096:biosynthesis / Q000276:immunology*; D060908:CTLA-4 Antigen; D002460:Cell Line; D016027:Heart Transplantation / Q000276:immunology*; D006801:Humans; D018796:Immunoconjugates; D007165:Immunosuppression Therapy / Q000379:methods*; D016031:Liver Transplantation / Q000276:immunology*; D051381:Rats; D011912:Rats, Inbred ACI; D011917:Rats, Inbred Lew; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000276:immunology; D012086:Reoperation; D014162:Transfection; D014184:Transplantation, Homologous
D015703:Antigens, CD; D000943:Antigens, Differentiation; D060908:CTLA-4 Antigen; C556706:CTLA4 protein, human; D018796:Immunoconjugates; D011994:Recombinant Proteins; D000069594:Abatacept