High-dose cellular IL-10 exacerbates rejection and reverses effects of cyclosporine and tacrolimus in Mouse cardiac transplantation.
Li
W
W
Thomas E. Starzl Transplantation Institute, University of Pittsburgh, Pennsylvania 15213, USA.
Lu
L
L
Li
Y
Y
Fu
F
F
Fung
J J
JJ
Thomson
A W
AW
Qian
S
S
D000818:Animals; D016572:Cyclosporine / Q000037:antagonists & inhibitors / Q000627:therapeutic use*; D006084:Graft Rejection / Q000276:immunology* / Q000473:pathology / Q000517:prevention & control; D016027:Heart Transplantation / Q000276:immunology* / Q000473:pathology / Q000502:physiology; D007166:Immunosuppressive Agents / Q000037:antagonists & inhibitors / Q000627:therapeutic use*; D016753:Interleukin-10 / Q000494:pharmacology*; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D008815:Mice, Inbred Strains; D009200:Myocardial Contraction; D013154:Spleen / Q000276:immunology; D013602:T-Lymphocytes, Cytotoxic / Q000276:immunology; D016559:Tacrolimus / Q000037:antagonists & inhibitors / Q000627:therapeutic use*
D007166:Immunosuppressive Agents; D016753:Interleukin-10; D016572:Cyclosporine; D016559:Tacrolimus