Heminasal aplasia: a case report and review of the literature of the last 25 years.
We report a child with right-sided heminasal aplasia in combination with anomalies of the right eye and maxilla. Unilateral aplasia of the nose is a rare congenital malformation. It is often associated with other malformations of the facial region, including abnormalities of the eye and lacrimal system, proboscis lateralis, and facial bone malformations. The eye anomalies in our patient consisted of microphthalmia with blepharophimosis and coloboma of the iris, retina and upper eyelid. Also hypoplasia of the lacrimal apparatus and right maxilla, and a rudimentary alveolar cleft on the same side were present. The embryological development of the midface can explain this association of anomalies.
van Kempen
A A
AA
Department of Neonatology, Academic Medical Center, Amsterdam, The Netherlands.
Nabben
F A
FA
Hamel
B C
BC
D000015:Abnormalities, Multiple / Q000473:pathology*; D005124:Eye Abnormalities / Q000473:pathology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007569:Jaw Abnormalities / Q000473:pathology*; D009666:Nose / Q000002:abnormalities*