Design criteria: tests used to assess platelet function.
A brief overview of platelet function tests used in the past to assess relations between dietary fatty acids and thrombogenicity reveals problems that need to be recognized and addressed before planning future studies. Implementation of new strategies that integrate new technologies with measures of two or more markers of platelet activity may be more successful in predicting the thrombotic potential of dietary fatty acids.
Schoene
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NW
Beltsville Human Nutrition Research Center, US Department of Agriculture 20705-2350, USA. nschoene@asrr.arsusda.gov
D000818:Animals; D001792:Blood Platelets / Q000187:drug effects / Q000502:physiology*; D004041:Dietary Fats / Q000009:adverse effects / Q000494:pharmacology; D004195:Disease Models, Animal; D005227:Fatty Acids / Q000009:adverse effects / Q000494:pharmacology; D006801:Humans; D010974:Platelet Aggregation / Q000187:drug effects; D010979:Platelet Function Tests / Q000379:methods* / Q000592:standards; D011237:Predictive Value of Tests; D051381:Rats; D013927:Thrombosis / Q000097:blood / Q000209:etiology / Q000503:physiopathology
D004041:Dietary Fats; D005227:Fatty Acids