Internalization of Aspergillus fumigatus conidia by epithelial and endothelial cells.
The internalization of conidia of the opportunistic fungus Aspergillus fumigatus by primary cell cultures of nonprofessional phagocytes was investigated. This study is the first to show that A. fumigatus conidia were able to be engulfed by tracheal epithelial, alveolar type II, and endothelial cells.
Paris
S
S
Laboratoire des Aspergillus, Institut Pasteur, Paris, France. sparis@pasteur.fr
Boisvieux-Ulrich
E
E
Crestani
B
B
Houcine
O
O
Taramelli
D
D
Lombardi
L
L
Latgé
J P
JP
D000818:Animals; D001232:Aspergillus fumigatus / Q000502:physiology*; D002460:Cell Line; D004730:Endothelium, Vascular / Q000382:microbiology* / Q000648:ultrastructure; D004848:Epithelium / Q000382:microbiology / Q000648:ultrastructure; D006801:Humans; D008854:Microscopy, Electron; D010587:Phagocytosis; D011817:Rabbits; D051381:Rats