[Pheochromocytoma-ganglioneuroma of the adrenal gland].
Two cases of a rare neuroectodermal compound tumor (pheochromocytoma-ganglioneuroma) of the adrenal were described. They were found in 2.85% of all neuroectodermal adrenal tumors investigated during 20 years. One tumor was diagnosed bioptically in a patient with hypertension. The other one was found incidentally in an autopsy. In both of the them, the major part was feochromocytoma. The structures of ganglioneuroma were only focal. Chromogranin A was relatively strongly positive in pheochromocytes which contained neurosecretory granules. In gangliocytes, the neuron-specific enolase was strongly and serotonin weakly expressed.
Dudorkinová
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II. patologickoanatomický ústav 1. LF UK a VFN, Praha.
D000310:Adrenal Gland Neoplasms / Q000473:pathology*; D000328:Adult; D005729:Ganglioneuroma / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D010673:Pheochromocytoma / Q000473:pathology*