title: Surface wettability enhancement of silicone hydrogel lenses by processing with polar plastic molds.
abstract: In the quest for hydrogel contact lenses with improved extended wear capability, the use of siloxane moieties in the lens materials was investigated. However, the introduction of hydrophobic siloxane groups gave rise to wettability and lipidlike deposit problems. It was found that when polysiloxane-based compositions for hydrogels were processed with polar plastic molds, such as those fabricated from an acrylonitrile-based polymer, the hydrogel lenses fabricated were wettable, with minimized lipidlike deposits. These findings were supported by the wettability of silicone hydrogel films, silicon, and nitrogen element contents near lens surfaces, as well as the results from clinical assessment of silicone hydrogel lenses.
authors.affiliation: Contact Lens Division, Bausch & Lomb Inc., Rochester, New York 14692, USA.
authors.forename: Y C
authors.initials: YC
authors.lastname: Lai
authors.forename: G D
authors.initials: GD
authors.lastname: Friends
mesh_terms: D003262:Contact Lenses, Extended-Wear; D003263:Contact Lenses, Hydrophilic; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D008422:Materials Testing; D010330:Patents as Topic; D010969:Plastics; D011091:Polyesters; D011092:Polyethylene Glycols; D011143:Polyvinyl Chloride; D012828:Silicones; D013499:Surface Properties; D014481:United States
chemical_list: D010969:Plastics; D011091:Polyesters; D012828:Silicones; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D011092:Polyethylene Glycols; D011143:Polyvinyl Chloride