Use of ceftizoxime screening for the detection of cephalosporin-resistant pneumococci.
Two hundred and ten pneumococcal isolates underwent ceftizoxime disk (30 micrograms) screening to predict cephalosporin resistance. Forty-six isolates failed screening with 36 (78%) demonstrating intermediate/resistant MICs. Sensitivity and specificity were 100 and 95%, respectively. The ceftizoxime disk screen is an effective method of identifying potentially cephalosporin-resistant isolates.
Schutze
G E
GE
University of Arkansas for Medical Sciences, Little Rock, USA.
Lewno
M J
MJ
Mason
E O
EO
D015296:Ceftizoxime / Q000494:pharmacology*; D018550:Cephalosporin Resistance; D002511:Cephalosporins / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D012680:Sensitivity and Specificity; D013296:Streptococcus pneumoniae / Q000187:drug effects*
D002511:Cephalosporins; D015296:Ceftizoxime