Dihydroisocoumarins from fungi: isolation, structure elucidation, circular dichroism and biological activity.
Five known and three new dihydroisocoumarins were isolated from different fungi. The new isocoumarins are 5-chloro-6-hydroxymellein, 5-chloro-4,6-dihydroxymellein and 5,6-dihydroxymellein. The absolute configuration of these secondary metabolites was confirmed by CD measurements and in two cases by X-ray structure analysis.
Krohn
K
K
Fachbereich Chemie und Chemietechnik der Universität-GH Paderborn, Germany.
Bahramsari
R
R
Flörke
U
U
Ludewig
K
K
Kliche-Spory
C
C
Michel
A
A
Aust
H J
HJ
Draeger
S
S
Schulz
B
B
Antus
S
S
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001410:Bacillus megaterium / Q000187:drug effects; D002708:Chlorella / Q000187:drug effects; D002942:Circular Dichroism; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D018360:Crystallography, X-Ray; D004926:Escherichia coli / Q000187:drug effects; D005658:Fungi / Q000737:chemistry* / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010944:Plants / Q000187:drug effects
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D003374:Coumarins