title: Oxazolidinones: new antibacterial agents.
abstract: The oxazolidinones are a new chemical class of synthetic antibacterial agents that are active orally or intravenously against multidrug-resistant Gram-positive bacteria. Their unique mechanism of action and activity against bacteria that pose therapeutic problems in hospital and community treatments make them promising candidates for antimicrobial agents.
authors.affiliation: Pharmacia & Upjohn Inc., Kalamazoo, MI 49001, USA.
authors.forename: C W
authors.initials: CW
authors.lastname: Ford
authors.forename: J C
authors.initials: JC
authors.lastname: Hamel
authors.forename: D
authors.initials: D
authors.lastname: Stapert
authors.forename: J K
authors.initials: JK
authors.lastname: Moerman
authors.forename: D K
authors.initials: DK
authors.lastname: Hutchinson
authors.forename: M R
authors.initials: MR
authors.lastname: Barbachyn
authors.forename: G E
authors.initials: GE
authors.lastname: Zurenko
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D001424:Bacterial Infections / Q000188:drug therapy; D017714:Community-Acquired Infections / Q000188:drug therapy; D003428:Cross Infection / Q000188:drug therapy; D006801:Humans; D010080:Oxazoles / Q000494:pharmacology*; D023303:Oxazolidinones; D010403:Penicillin Resistance
chemical_list: D000900:Anti-Bacterial Agents; D010080:Oxazoles; D023303:Oxazolidinones; C054755:4-acetylphenyloxooxazolidinylmethylacetamide