Toxoplasma infection in healthy persons and in patients with HIV or ocular disease.
Toxoplasma infection is associated with acquired immune deficiency syndrome (AIDS), pregnancy, chorioretinitis, etc. Since the number of AIDS patients is increasing rapidly in Thailand and there are few reports about T. gondii immune status in this country. Toxoplasma-specific IgG and IgM antibodies (Ab) were determined in healthy persons and patients with different symptoms who were suspected of toxoplasmosis. Specific IgG Ab were detected in 3.2% of healthy persons, 12.5% of patients with ocular disease and in 42.5% in HIV positive patients. Only 3.1% of patients with ocular disease were positive for specific IgM Ab. No specific IgM Ab were found in the other samples studied.
Wongkamchai
S
S
Department of Clinical Pathology, Faculty of Medicine, Mahidol University, Bangkok, Thailand.
Rungpitaransi
B
B
Wongbunnate
S
S
Sittapairochana
C
C
D017088:AIDS-Related Opportunistic Infections / Q000276:immunology*; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood; D002353:Carrier State / Q000276:immunology*; D002648:Child; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D017678:Sex Distribution; D013785:Thailand; D014122:Toxoplasma / Q000276:immunology; D014123:Toxoplasmosis / Q000276:immunology*; D014126:Toxoplasmosis, Ocular / Q000276:immunology*
D000913:Antibodies, Protozoan; D007074:Immunoglobulin G; D007075:Immunoglobulin M