[Quinidine-induced rheumatic toxicity].
2 women with quinidine-induced lupus are presented. This condition is rare; only about 30 cases have been reported in the English literature. Both our patients had arthritis of the wrist, antinuclear antibodies with homogenous pattern and elevated ESR. Anti-double stranded DNA antibodies were present in 1 patient, and a petechial rash in the other. Complete resolution of arthritis occurred within a few days after quinidine withdrawal, but antinuclear antibodies persisted for several months.
Almoznino-Sarafian
D
D
Dept. of Medicine C, Assaf Harofeh Medical Center, Zerifin.
Cohen
N
N
Zaidenstein
R
R
Dishi
V
V
Zeckler
E
E
D000368:Aged; D000369:Aged, 80 and over; D001168:Arthritis / Q000139:chemically induced / Q000276:immunology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced*; D008875:Middle Aged; D011802:Quinidine / Q000009:adverse effects*; D014955:Wrist Joint
D011802:Quinidine