The role of boron MRI in boron neutron capture therapy.
Boron magnetic resonance imaging (MRI) and spectroscopy (MRS) are being developed for use in boron neutron capture therapy (BNCT). With continued development, boron MRI may be used to locate BNCT agents in vivo, evaluate the pharmacokinetics of BNCT agents, and aid in treatment planning.
Kabalka
G W
GW
University of Tennessee Biomedical Imaging Center, Knoxville 37920, USA.
Tang
C
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Bendel
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D000818:Animals; D001894:Borohydrides / Q000032:analysis* / Q000493:pharmacokinetics; D001895:Boron; D016754:Boron Neutron Capture Therapy / Q000379:methods*; D001921:Brain / Q000378:metabolism*; D001932:Brain Neoplasms / Q000378:metabolism* / Q000532:radiotherapy* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D051381:Rats; D011916:Rats, Inbred F344; D013438:Sulfhydryl Compounds / Q000032:analysis* / Q000493:pharmacokinetics
D001894:Borohydrides; D013438:Sulfhydryl Compounds; C014651:mercaptoundecahydrododecaborate; D001895:Boron