A bioactive triterpene from Lantana camara.
Lantana camara afforded a novel triterpene 22 beta-acetoxylantic acid and the known triterpenes, lantic acid, 22 beta-dimethylacryloyloxylantonolic acid, a mixture of 22 beta-dimethylacryloyloxy lantanolic acid and 22 beta-angeloyloxylantanolic acid and lantanolic acid. 22 beta-Acetoxylantic acid showed antimicrobial activity against Staphylococcus aureus and Salmonella typhi. This compound and 22 beta-dimethylacryloyloxy lantanolic acid also showed antimutagenic activity.
Barre
J T
JT
Chemistry Department, De La Salle University, Manila, Philippines
Bowden
B F
BF
Coll
J C
JC
DeJesus
J
J
De La Fuente
V E
VE
Janairo
G C
GC
Ragasa
C Y
CY
D000818:Animals; D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000633:toxicity; D016587:Antimutagenic Agents / Q000302:isolation & purification / Q000633:toxicity; D001419:Bacteria / Q000187:drug effects; D051379:Mice; D015162:Micronucleus Tests; D018515:Plant Leaves / Q000737:chemistry; D014315:Triterpenes / Q000302:isolation & purification* / Q000633:toxicity
D000900:Anti-Bacterial Agents; D016587:Antimutagenic Agents; D014315:Triterpenes