Comparison between urea removal in hemodialysis and continuous ambulatory peritoneal dialysis using a mathematical kinetic model.
Urea removal by continuous ambulatory peritoneal dialysis (CAPD) was compared with that by hemodialysis (HD) using a mathematical kinetic model. The time-averaged urea-nitrogen concentration (TAC) in the blood of a patient on maintenance HD was calculated by the model. Clearance with HD giving a TAC value equal to the constant urea-nitrogen concentration in the blood of a patient on CAPD was obtained, leading to the relation of equivalent clearances between HD and CAPD on the assumption that the urea-generation rate of the patient on CAPD was equal to that of the patient on HD.
Kanamori
T
T
Department of Polymer Engineering, National Institute of Materials and Chemical Research, Ibaraki, Japan.
Sakai
K
K
D001806:Blood Urea Nitrogen; D006801:Humans; D007700:Kinetics; D008954:Models, Biological; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000592:standards*; D006435:Renal Dialysis / Q000592:standards*; D014508:Urea / Q000302:isolation & purification*
D014508:Urea