title: Maternal plasma estrone sulfate profile during pregnancy in the cow; comparison between singleton and twin pregnancies.
abstract: Peripheral plasma estrone sulfate (E(1)-S) concentrations were characterized throughout gestation in singleton and twin bearing cows by a direct radioimmunoassay method. Maternal plasma E1-S was detectable from around day 100 and after that its concentration increased progressively to term in both singleton (n = 5) and twin bearing (n = 5) cows. Twin bearing cows had a significantly higher E1-S concentrations in some time from mid-gestation to term when compared to singleton cows. E1-S concentration in the twin bearing cows increased rapidly in the third trimester and peaked (16.7 ng/ml) on the day of calving. In the singleton cows the concentration increased gradually and peaked (7.1 ng/ml) about 10 days before calving and then subsequently decreased. Our results indicate that singleton and twin bearing cows show a disparate E1-S profile from mid-gestation to term.
authors.affiliation: Department of Animal Reproduction, National Institute of Animal Industry, Tsukuba, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Takahashi
authors.forename: M
authors.initials: M
authors.lastname: Hirako
authors.forename: H
authors.initials: H
authors.lastname: Takahashi
authors.forename: O V
authors.initials: OV
authors.lastname: Patel
authors.forename: N
authors.initials: N
authors.lastname: Takenouchi
authors.forename: I
authors.initials: I
authors.lastname: Domeki
mesh_terms: D000818:Animals; D002417:Cattle / Q000097:blood*; D004970:Estrone / Q000031:analogs & derivatives* / Q000097:blood; D005260:Female; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000097:blood*; D011272:Pregnancy, Multiple / Q000097:blood*; D011863:Radioimmunoassay / Q000379:methods / Q000662:veterinary; D014427:Twins
chemical_list: D004970:Estrone; C017296:estrone sulfate