title: Dedifferentiated parosteal osteosarcoma of the radius.
abstract: A 35-year-old woman presented with a painful swelling in the left distal radius that had been present for 1 year. Radiography and computerized tomography revealed a sclerotic surface lesion that had grown over the year and eroded the cortex. Histological examination demonstrated two distinct components: a cartilaginous low- to moderate-grade osteosarcoma on the surface and a high-grade osteosarcoma in the intramedullary component. This case is uncommon in two aspects: the radius is a rare site for such a tumor and the dedifferentiation was revealed at the time of the first surgery and was not secondary to recurrence.
authors.affiliation: Department of Radiology, Mount Sinai Hospital and School of Medicine, City University of New York, New York, USA.
authors.forename: I F
authors.initials: IF
authors.lastname: Abdelwahab
authors.forename: S
authors.initials: S
authors.lastname: Kenan
authors.forename: G
authors.initials: G
authors.lastname: Hermann
authors.forename: M J
authors.initials: MJ
authors.lastname: Klein
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D018217:Osteosarcoma, Juxtacortical / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D011884:Radius; D014057:Tomography, X-Ray Computed