[Possible use of erythrocyte antioxidant enzymes as markers of the course of disease in patients with hemoblastoses].
Blood and erythrocytes of 50 healthy volunteers and 105 patients with different forms of hemoblastoses were investigated. 54 patients had acute phase, 51 patients--remission stage of disease. Essential differences in the activity of antioxidant enzymes (SOD, CAT, GSH-Px) were detected and compared with content of MDA and degree of anaemia. Acute phase had more significantly alteration of antioxidant defence: diverse changes of the activity of SOD and CAT, significantly inhibition of GSH-Px, the high level of MDA and increased degree of anaemia.
Kumerova
A O
AO
Petukhov
V I
VI
Shkesters
A P
AP
Silova
A A
AA
Letse
A G
AG
D000328:Adult; D000368:Aged; D002374:Catalase / Q000097:blood*; D004796:Clinical Enzyme Tests; D004912:Erythrocytes / Q000201:enzymology*; D005979:Glutathione Peroxidase / Q000097:blood; D019337:Hematologic Neoplasms / Q000175:diagnosis*; D006801:Humans; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D011379:Prognosis; D013482:Superoxide Dismutase / Q000097:blood*
D008315:Malondialdehyde; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase
Vozmozhnost' ispol'zovaniia antioksidantnykh fermentov éritrotsitov v kachestve indikatorov, kharakterizuiushchikh techenie bolezni u bol'nykh gemoblastozami.