[Isolation of band-specific (CA)n microsatellites from human chromosome 8q24.1].
Fourty eight recombinant plasmids containing CA repeats were isolated from human chromosome 8q24.1 band-specific pUC19 library. Among them, inserted DNA fragments from 12 plasmids were sequenced, and one new highly polymorphic (CA)n microsatellite was obtained (coding: D8S7F). It contained 11 alleles. The estimated heterozygosity reached 0.84 and 0.83 among Chinese Han Nationality people and American Anglo-Saxons respectively. It was assigned to chromosome 8 by using a human-rodent hybrid cell panel.
Xu
L
L
National Laboratory of Medical Genetics, Human Medical University, Changsha.
Xia
J
J
Pan
Q
Q
Cai
T
T
Deng
H
H
D001483:Base Sequence; D002898:Chromosomes, Human, Pair 8; D015723:Gene Library; D006801:Humans; D018895:Microsatellite Repeats; D008969:Molecular Sequence Data