title: Surgical tactics in the treatment of malignant renal tumors in childhood.
abstract: The authors report the treatment results of 89 children with renal tumors (excluding carcinoma) seen from 1988 to 1992, 71 (79.8%) with favorable-histology Wilms' tumor (survival 86%) and 18 (20.2%) with unfavorable histology, including anaplastic nephroblastoma, clear-cell sarcoma, and rhabdoid tumor (survival 61%). Preoperative chemotherapy (ChT) was given to 46 patients (survival 84%); none was given to 43 with either tumors in the 1st year of life, massive hematuria, or tumor growth during ChT (survival 78%). There were 3 tumor ruptures in the latter group compared to 1 in the former group.
authors.affiliation: Department of Pediatric Surgery, Motol Children's Hospital, 2nd Medical School, Charles' University in Prague, 15018 Prague 5, Czech Republic.
authors.forename: K
authors.initials: K
authors.lastname: Pýcha
authors.forename: J
authors.initials: J
authors.lastname: Snajdauf
authors.forename: J
authors.initials: J
authors.lastname: Koutecký
authors.forename: R
authors.initials: R
authors.lastname: Kodet
authors.forename: M
authors.initials: M
authors.lastname: Zítková
mesh_terms: D017024:Chemotherapy, Adjuvant; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007668:Kidney / Q000473:pathology; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008297:Male; D009367:Neoplasm Staging; D009392:Nephrectomy; D018335:Rhabdoid Tumor / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018227:Sarcoma, Clear Cell / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate; D009396:Wilms Tumor / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000601:surgery*