Solid tumours in newborns and infants.
Thirty two cases of solid tumours in newborns and infants were observed by the authors over a 15 year period. The most common type of tumours were soft tissue tumours (n = 8), neuroblastomas (n = 7), nephroblastomas (n = 5) and germ cell tumours (n = 5). Other types of embryonal tumours such as retinoblastoma and hepatoblastoma were observed in four children and non-Hodgkin's lymphomas in three children. Of 25 children followed up 18 survived. Five children died of their tumours and two children died of causes unrelated to their basic disease. Analysis of the fate of the patients and the effect of the therapy is made. It is concluded that malignant tumours prevail in infancy (90.6% of all cases). The percentage of patients treated successfully with insignificant risk for consequences from radiotherapy and chemotherapy is also high (72%).
Chakova
L
L
Department of Pediatrics, University of Medicine, Plovdiv, Bulgaria.
Stoyanova
A
A
D005260:Female; D018197:Hepatoblastoma / Q000151:congenital* / Q000473:pathology / Q000628:therapy; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008228:Lymphoma, Non-Hodgkin / Q000151:congenital* / Q000473:pathology / Q000628:therapy; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000151:congenital* / Q000473:pathology / Q000628:therapy; D012983:Soft Tissue Neoplasms / Q000151:congenital* / Q000473:pathology / Q000628:therapy; D015996:Survival Rate; D009396:Wilms Tumor / Q000151:congenital* / Q000473:pathology / Q000628:therapy