Effects of diet on urinary bladder carcinogenesis and cancer prevention.
Urine plays a major role in bladder carcinogenesis, acting as a transport mechanism for carcinogens, containing several growth factors stimulating cell proliferation, and indirectly affecting chemicals by alterations in concentrations of normal urinary components such as electrolytes, water and proteins. These latter effects are greatly modified by diet composition and consumption and also by water consumption. Several examples of these effects are presented.
Cohen
S M
SM
Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha.
Masui
T
T
Garland
E M
EM
Arnold
L L
LL
D000818:Animals; D016588:Anticarcinogenic Agents; D002273:Carcinogens; D004032:Diet; D006801:Humans; D009153:Mutagens; D012439:Saccharin / Q000009:adverse effects; D001749:Urinary Bladder Neoplasms / Q000139:chemically induced* / Q000517:prevention & control*
D016588:Anticarcinogenic Agents; D002273:Carcinogens; D009153:Mutagens; D012439:Saccharin