title: The relationship between juxtapapillary duodenal diverticula and biliary stone disease.
abstract: OBJECTIVE
  To assess the relationship between juxtapapillary duodenal diverticula (JDD) and common bile duct stones and biliary stone disease in general.
  
  
  METHODS
  A retrospective study.
  
  
  METHODS
  We analysed 1115 patients who underwent consecutive endoscopic retrograde cholangiopancreatography examinations. The patients were subdivided into three groups: the first group (group I; n = 482) had no biliary stone disease, the second one (group II; n = 329) had common bile duct stones, and the third group (group III; n = 304) had biliary stone disease of the gallbladder but without evidence of common bile duct stones. Additionally, the patients were subdivided into age groups of < 50, 50-59, 60-69, 70-79, and > or = 80 years of age. Logistic regression was applied for statistical analysis.
  
  
  RESULTS
  Juxtapapillary duodenal diverticula were diagnosed in 111 (10.0%) patients. The incidence of JDD was 6.9% in group I, 14.3% in group II and 10.2% in group III. Age was the most dominant influence factor for JDD, common bile duct stones, and biliary stone disease (P < 0.0001). Sex was also a factor, female patients having a higher risk for common bile duct stones (P = 0.01) and biliary stone disease (P < 0.0001). After adjustment for age and sex, JDD was found to have a noticeable, but not statistically significant (P = 0.073), influence on common bile duct stones and no influence on biliary stone disease (P = 0.15).
  
  
  CONCLUSIONS
  Our data support only moderately the existence of a relationship, which had been conjectured in a part of the literature, between JDD and common bile duct stones. No noticeable influence on biliary stone disease was found.
authors.affiliation: Department of Internal Medicine IV, University of Vienna, Austria.
authors.forename: G
authors.initials: G
authors.lastname: Novacek
authors.forename: M
authors.initials: M
authors.lastname: Walgram
authors.forename: P
authors.initials: P
authors.lastname: Bauer
authors.forename: R
authors.initials: R
authors.lastname: Schöfl
authors.forename: A
authors.initials: A
authors.lastname: Gangl
authors.forename: R
authors.initials: R
authors.lastname: Pötzi
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods; D002769:Cholelithiasis / Q000150:complications* / Q000175:diagnosis / Q000453:epidemiology; D004240:Diverticulum / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D004378:Duodenal Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D016145:Endoscopy, Digestive System; D005260:Female; D042882:Gallstones / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D012189:Retrospective Studies; D012737:Sex Factors