[Experimental study of the effect of formaldehyde during embryogenesis on the activity of rat liver enzyme systems in ontogenesis].
The pregnant rats were treated with formaldehyde (0.5 mg/kg daily per os) during whole period of pregnancy. The activity of cytochrome-c-oxidase, malate dehydrogenase, nucleotidase, glucose-6-phosphatase, beta-glucuronidase, N-acetyl-beta-glucosaminidase, beta-galactosidase, H(+)-ATPase, glutamate dehydrogenase, NAD- and NADP-isocitrate dehydrogenase, fructose-bisphosphate aldolase, glucose-6-phosphate dehydrogenase and content of protein in liver celts of offsprings (newborns, 2 weeks age and 2 months age) were studied. It was shown differences in development enzyme systems of control and experimental animals during ontogenesis.
Astakhova
L F
LF
Mukhambetova
L Kh
LKh
Koganova
Z I
ZI
Dolinskaia
S I
SI
Kazachkov
V I
VI
Zhurkov
V S
VS
D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development* / Q000378:metabolism; D005314:Embryonic and Fetal Development / Q000187:drug effects*; D004734:Energy Metabolism / Q000187:drug effects; D005260:Female; D005557:Formaldehyde / Q000633:toxicity*; D008099:Liver / Q000187:drug effects / Q000196:embryology / Q000201:enzymology*; D008297:Male; D011247:Pregnancy; D051381:Rats
D005557:Formaldehyde
Eksperimental'noe izuchenie vozdeĭstviia formal'degida v period émbriogeneza na aktivnost' fermentnykh sistem pecheni krys v ontogeneze.