title: Hemodynamic changes in the inferior caval vein during pneumoperitoneum. An experimental study in pigs.
abstract: BACKGROUND
  Laparoscopic procedures of increasing difficulty and duration are becoming more and more common. This may cause significant challenges to the circulatory system and possibly influence thrombogenicity.
  
  
  METHODS
  Experimental study of carbon dioxide pneumoperitoneum in pigs.
  
  
  RESULTS
  Inferior caval vein blood flow remained unchanged, whereas inferior caval vein pressure increased during pneumoperitoneum. Inferior caval vein, pulmonary, and systemic vascular resistance increased during pneumoperitoneum and remained increased after exsufflation.
  
  
  CONCLUSIONS
  Pneumoperitoneum leads to an increased inferior caval vein pressure, which could cause a dilation of peripheral veins. The similar patterns of vascular resistance in the inferior caval vein, pulmonary artery, and systemic arteries (a gradual increase remaining elevated after exsufflation) suggest a common humoral factor or increased sympathetic nerve activity.
authors.affiliation: Department of Surgery, University Hospital, S-751 85 Uppsala, Sweden.
authors.forename: F
authors.initials: F
authors.lastname: Lindberg
authors.forename: D
authors.initials: D
authors.lastname: Bergqvist
authors.forename: I
authors.initials: I
authors.lastname: Rasmussen
authors.forename: U
authors.initials: U
authors.lastname: Haglund
mesh_terms: D000818:Animals; D002245:Carbon Dioxide / Q000008:administration & dosage; D005260:Female; D006439:Hemodynamics; D008297:Male; D011028:Pneumoperitoneum, Artificial / Q000295:instrumentation / Q000379:methods / Q000706:statistics & numerical data; D013552:Swine; D013997:Time Factors; D014682:Vena Cava, Inferior / Q000502:physiology*
chemical_list: D002245:Carbon Dioxide