title: Deficient antisaccades in the social-emotional processing disorder.
abstract: We investigated whether adolescents and adults with the developmental social-emotional processing disorder (SEPD) exhibit deficits in visual attention, as measured by eye movements, when compared with dyslexic and normal control subjects. On the antisaccade task, subjects with SEPD made more errors than either control group and were the only group to show a decrease in performance accuracy compared with prosaccade. This deficit in inhibiting reflexive shifts of attention and gaze suggests that individuals with SEPD have dysfunction of the prefrontal component of the right hemisphere dominant network for spatially directed attention.
authors.affiliation: Behavioral Neurology Unit, Beth Israel Hospital, Boston, MA 02215, USA.
authors.forename: D S
authors.initials: DS
authors.lastname: Manoach
authors.forename: S
authors.initials: S
authors.lastname: Weintraub
authors.forename: K R
authors.initials: KR
authors.lastname: Daffner
authors.forename: L F
authors.initials: LF
authors.lastname: Scinto
mesh_terms: D000293:Adolescent; D000328:Adult; D001288:Attention; D004410:Dyslexia / Q000503:physiopathology; D004644:Emotions; D005260:Female; D006801:Humans; D007859:Learning Disabilities / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011930:Reaction Time; D012438:Saccades / Q000502:physiology*; D013577:Syndrome; D013995:Time