title: Disintegration of cervical intervertebral BOP grafts with neurological sequelae: a report of two cases.
abstract: We report the case histories of two patients treated in our unit for cervical radiculopathy by anterior cervical discectomy and BOP grafting. Both grafts disintegrated within 6 weeks of insertion resulting in increased neurological deficit from cervical cord compression. At reoperation fibres from the grafts were found to have separated and the larger fragments had extruded into the vertebral canal. No evidence of infection was seen, but a foreign body reaction was found in one case. Following graft removal the patients improved symptomatically although one was left with permanent mild biceps weakness.
authors.affiliation: Regional Neurosciences Unit, Charing Cross Hospital, London, UK.
authors.forename: N L
authors.initials: NL
authors.lastname: Dorward
authors.forename: N N
authors.initials: NN
authors.lastname: Malik
authors.forename: R D
authors.initials: RD
authors.lastname: Illingworth
mesh_terms: D001672:Biocompatible Materials; D005260:Female; D005549:Foreign-Body Reaction / Q000150:complications*; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000601:surgery*; D008768:Methylmethacrylates; D008875:Middle Aged; D011205:Povidone; D019736:Prostheses and Implants; D011475:Prosthesis Failure; D013117:Spinal Cord Compression / Q000209:etiology*
chemical_list: D001672:Biocompatible Materials; D008768:Methylmethacrylates; C037334:poly(methylmethacrylate-N-vinylpyrrolidone); D011205:Povidone