title: Occupational toxicology: test methods and approaches for the pharmaceutical industry.
abstract: Occupational toxicologists consider the intended pharmacologic effects of active substances to be adverse and undesirable in healthy workers, because of the absence of any therapeutic benefit. This chapter covers testing of finished agents as well as intermediates and related materials for determining exposure routes and potential toxicity.
authors.affiliation: SmithKline Beecham Corporation, King of Prussia, PA, USA.
authors.forename: G
authors.initials: G
authors.lastname: Sprague
authors.forename: T
authors.initials: T
authors.lastname: Sutton
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems; D004345:Drug Industry; D004784:Environmental Monitoring / Q000379:methods; D015386:Hazardous Substances / Q000506:poisoning*; D006801:Humans; D009784:Occupational Diseases / Q000139:chemically induced* / Q000517:prevention & control; D016273:Occupational Exposure / Q000009:adverse effects; D012308:Risk Management / Q000379:methods*; D014116:Toxicology / Q000379:methods*; D014481:United States
chemical_list: D015386:Hazardous Substances