Three-dimensional structure of staphylokinase, a plasminogen activator with therapeutic potential.
The three-dimensional structure of staphylokinase has been determined at 1.8 A. The puntative site of interaction with plasminogen was identified and epitopes were mapped.
Rabijns
A
A
De Bondt
H L
HL
De Ranter
C
C
D018360:Crystallography, X-Ray; D016056:Immunodominant Epitopes / Q000032:analysis; D008666:Metalloendopeptidases / Q000737:chemistry*; D008958:Models, Molecular; D010960:Plasminogen Activators / Q000737:chemistry*; D011994:Recombinant Proteins / Q000737:chemistry; D013211:Staphylococcus aureus / Q000201:enzymology
D016056:Immunodominant Epitopes; D011994:Recombinant Proteins; D010960:Plasminogen Activators; D008666:Metalloendopeptidases; C022653:auR protein, Staphylococcus aureus