title: [Importance of iterative reconstruction ISA in the diagnosis of liver hemangioma].
abstract: OBJECTIVE
  To evaluate whether the iterative reconstruction methodology ISA is superior to the standard technique of filtered back-projection.
  
  
  METHODS
  In a retrospective study, we evaluated images of 39 patients with solitary or multiple liver tumors who underwent blood pool imaging in SPECT technique in order to prove or exclude the presence of hemangioma.
  
  
  RESULTS
  Activity accumulations in accordance with the diagnosis of liver hemangioma could be visualized in 34 cases by the iterative, in 31 cases by the filtered back-projection methodology. As compared to filtered back-projection, the iteratively reconstructed lesions showed higher tumor-to-background ratios and were more easily distinguished from structures in their neighborhood. Furthermore, the iterative methodology resulted in a more homogeneous activity distribution in the liver, whereas the inhomogeneous "patchy" structure of the liver parenchyma in filtered back-projection provokes difficulties in the distinction from reconstruction artifacts. A clearer visualization of vessels and a better distinction between the right kidney and the liver was possible by the iterative algorithm, leading to advantages in the recognition of centrally or dorsally located lesions in the right hepatic lobe.
  
  
  CONCLUSIONS
  These data indicate that the use of our iterative algorithm in performing liver blood pool imaging yields a higher sensitivity and a better diagnostic accuracy in diagnosing liver hemangioma.
authors.affiliation: Abteilung für Nuklearmedizin der Universität Göttingen, Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Meller
authors.forename: M
authors.initials: M
authors.lastname: Conrad
authors.forename: T
authors.initials: T
authors.lastname: Behr
authors.forename: S
authors.initials: S
authors.lastname: Gratz
authors.forename: H
authors.initials: H
authors.lastname: Luig
authors.forename: W
authors.initials: W
authors.lastname: Becker
mesh_terms: D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D006391:Hemangioma / Q000000981:diagnostic imaging*; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
vernacular_title: Bedeutung der iterativen Rekonstruktion ISA bei der Diagnostik von Leberhämangiomen.