Physiologic motion after laryngeal nerve reinnervation: a new method.
In this study a new method of reinnervation for unilateral recurrent laryngeal nerve paralysis was performed in canines, producing physiologic vocal fold motion in each of a small series of animals. During the procedure the left anterior division of the recurrent laryngeal nerve was reinnervated with axons from the thyroarytenoid branch of the contralateral recurrent laryngeal nerve. The posterior branch of the left recurrent laryngeal nerve was divided and sutured to the ansa cervicalis to maintain tone in the posterior cricoarytenoid muscle. In all four animals, the right distal vocalis stump was reinnervated with an ansa cervicalis nerve branch. After 3 months physiologic vocal fold motion and electromyographic activity could be demonstrated during mechanical stimulation of the supraglottis (adduction) and during tracheostomy obstruction (abduction). Acoustic data revealed improvement of jitter, shimmer, signal-to-noise ratio, and vocal efficiency in reinnervated animals compared with paralyzed canines before treatment, although the results lacked statistical significance. This approach to the rehabilitation of unilateral vocal fold paralysis is discussed.
Sercarz
J A
JA
Division of Head and Neck Surgery, UCLA School of Medicine, Los Angeles, CA 90024-1624, USA.
Nguyen
L
L
Nasri
S
S
Graves
M C
MC
Wenokur
R
R
Berke
G S
GS
D000162:Acoustics; D000714:Anastomosis, Surgical; D000818:Animals; D001369:Axons; D002572:Cervical Plexus / Q000601:surgery; D004285:Dogs; D004576:Electromyography; D005931:Glottis / Q000502:physiology; D007821:Laryngeal Muscles / Q000294:innervation; D007828:Laryngoscopy; D009068:Movement; D016067:Nerve Transfer; D010812:Physical Stimulation; D012009:Recurrent Laryngeal Nerve / Q000601:surgery*; D014139:Tracheostomy; D014741:Video Recording; D014826:Vocal Cord Paralysis / Q000601:surgery*; D014827:Vocal Cords / Q000502:physiology*; D014828:Vocalization, Animal / Q000502:physiology