Antibiotic prophylaxis in ultrasound guided transrectal prostate biopsy.
OBJECTIVE
A retrospective review of a large group of transrectal ultrasound guided biopsies was performed to determine the symptomatic urinary tract infection rate associated with a consistent and defined antibiotic prophylaxis regimen.


METHODS
A total of 4,439 biopsies was performed using an 18 gauge needle with ultrasound guidance. Patients were treated with 500 mg. ciprofloxacin twice daily for 8 doses beginning the day before biopsy.


RESULTS
Of 5 symptomatic urinary tract infections noted 3 were complicated.


CONCLUSIONS
These data demonstrate the low infection rate associated with this prophylaxis regimen.
Sieber
P R
PR
Urological Associates of Lancaster, Ltd., Pennsylvania.
Rommel
F M
FM
Agusta
V E
VE
Breslin
J A
JA
Huffnagle
H W
HW
Harpster
L E
LE
D000890:Anti-Infective Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D001707:Biopsy, Needle / Q000009:adverse effects* / Q000379:methods; D002939:Ciprofloxacin / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000000981:diagnostic imaging / Q000473:pathology*; D012189:Retrospective Studies; D014463:Ultrasonography; D014552:Urinary Tract Infections / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*
D000890:Anti-Infective Agents; D002939:Ciprofloxacin