Azathioprine-induced pericarditis in a patient with ulcerative colitis.
Inflammatory bowel disease is rarely associated with pericarditis but both sulfasalazine and the aminosalicylates have been known to cause this complication. To the author's knowledge this is the first reported case of acute pericarditis caused by azathioprine. It is believed that pericarditis is yet another potential manifestation of hypersensitivity to this drug.
Simpson
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Department of Medicine, Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, Nova Scotia.
D000328:Adult; D000963:Antimetabolites / Q000009:adverse effects* / Q000627:therapeutic use; D001379:Azathioprine / Q000009:adverse effects* / Q000627:therapeutic use; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D003937:Diagnosis, Differential; D004452:Echocardiography; D004562:Electrocardiography; D006801:Humans; D008297:Male; D010493:Pericarditis / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology
D000963:Antimetabolites; D001379:Azathioprine