title: Role of hypo-osmotic sperm swelling test in assisted reproduction.
abstract: Hypo-osmotic sperm swelling (HOS) profile is found to be a better predictor of the fertilisability in those husbands possessing subnormal semen parameters. The group where husband's HOS gradings were less than 60%, no one could conceive his fertile wife even after intra-uterine insemination (IUI) for 8 times. However, in the other group where the HOS values were greater than 60%, conception were registered in 6 oligospermic and 2 asthenospermic husbands after 2 to 8 IUI amongst 22 married couples. No conception occurred in any normal coital cycle. All the pregnancies were delivered by elective caesarean section (4 females and 3 males), their birth weights were 2.705 +/- 0.425 kg. One aborted spontaneously at 10 weeks' gestation. The emerging fact in this study is where the HOS values are below 60% the male fertility is reduced, the chances of conception are trivial but fecundity is relatively fair where HOS reading is greater than 60%. It is also a no risk and high benefit method to pick and choose subfertile husbands who are likely to conceive their fertile wives by assisted reproductive techniques.
authors.affiliation: Department of Obstetrics and Gynaecology, Nilratan Sircar Medical College, Calcutta.
authors.forename: S
authors.initials: S
authors.lastname: Datta
authors.forename: A
authors.initials: A
authors.lastname: Giri
authors.forename: A K
authors.initials: AK
authors.lastname: Datta
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007038:Hypotonic Solutions; D007194:India; D007248:Infertility, Male / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D007317:Insemination, Artificial, Homologous; D008297:Male; D011247:Pregnancy; D011379:Prognosis; D013076:Sperm Count; D013084:Sperm-Ovum Interactions / Q000502:physiology*; D013094:Spermatozoa / Q000502:physiology*; D014882:Water-Electrolyte Balance / Q000502:physiology*
chemical_list: D007038:Hypotonic Solutions