Physiological background of enuresis type I. A preliminary report.
The physiological background of enuresis Type I, which is due to a mild arousal dysfunction, has been investigated in two studies, one in rats and one in children with Type I enuresis. The results of these investigations suggest that in this type of enuresis, the fundamental arousal function following bladder distension, due to an arousal centre like the locus coeruleus and its network, is normal. In contrast, the process of multiplying the transient connection from light sleep to complete awakening, which probably relies upon functions of the thalamus and the further upper centrums, was thought to be abnormal.
Watanabe
H
H
Department of Urology, Kyoto Prefectural University of Medicine, Japan.
Imada
N
N
Kawauchi
A
A
Koyama
Y
Y
Shirakawa
S
S
D000818:Animals; D001143:Arousal / Q000502:physiology*; D002675:Child, Preschool; D004195:Disease Models, Animal; D004569:Electroencephalography; D004775:Enuresis / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D008125:Locus Coeruleus / Q000502:physiology*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012894:Sleep Stages / Q000502:physiology*; D001743:Urinary Bladder / Q000502:physiology