title: Anterior ischemic optic neuropathy in a patient with positive antinuclear antibody and lupus anticoagulant findings.
abstract: A 64-year-old woman complained of blurred vision in her right eye. A pale optic disc with a blurred nasal margin was found in the right fundus. An inferior altitudinal defect in the right eye was observed on Goldmann perimetry. Her right visual acuity deteriorated to 0.1. Her antinuclear antibody and lupus anticoagulant test results were positive. Intravenous methylprednisolone (1,000 mg/day) improved her right visual acuity to 1.0. We believe that the anterior ischemic optic neuropathy in our patient may be associated with the presence of positive antinuclear antibody and lupus anticoagulant findings.
authors.affiliation: Department of Ophthalmology, Toyama Medical and Pharmaceutical University, Toyama, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Togashi
authors.forename: K
authors.initials: K
authors.lastname: Numata
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
authors.forename: S
authors.initials: S
authors.lastname: Hayasaka
mesh_terms: D000974:Antibodies, Antinuclear / Q000276:immunology*; D004596:Electroretinography; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D016682:Lupus Coagulation Inhibitor / Q000276:immunology*; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D009898:Optic Disk / Q000098:blood supply / Q000473:pathology; D018917:Optic Neuropathy, Ischemic / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology; D014792:Visual Acuity; D058609:Visual Field Tests
chemical_list: D000974:Antibodies, Antinuclear; D005938:Glucocorticoids; D016682:Lupus Coagulation Inhibitor; D008775:Methylprednisolone