title: Review article: controversy in the therapy of gastro-oesophageal reflux disease--long-term proton pump inhibition or laparoscopic anti-reflux surgery?
abstract: The treatment of gastro-oesophageal reflux disease is controversial. Whilst medical treatment is successful in patients with mild to moderate disease, the threshold of severity above which an operation should be contemplated remains a matter for debate. Laparoscopic anti-reflux surgery may be lowering this threshold, as this form of therapy provides several advantages over its open counterpart, but it is not without risk, and few long-term results are available. This article reviews treatment options for reflux disease and examines the relative position of current medical and surgical therapies.
authors.affiliation: Blackpool Victoria Hospital, UK.
authors.forename: S J
authors.initials: SJ
authors.lastname: Walker
authors.forename: S T
authors.initials: ST
authors.lastname: Baxter
authors.forename: A I
authors.initials: AI
authors.lastname: Morris
authors.forename: R
authors.initials: R
authors.lastname: Sutton
mesh_terms: D005764:Gastroesophageal Reflux / Q000188:drug therapy* / Q000209:etiology / Q000601:surgery*; D006801:Humans; D010535:Laparoscopy; D054328:Proton Pump Inhibitors
chemical_list: D054328:Proton Pump Inhibitors