title: Flow cytometry tear analysis in patients with chronic allergic conjunctivitis.
abstract: Tears from patients with chronic allergic conjunctivitis were analyzed with flow cytometry to determine the function of the T lymphocyte-related immunological reactions in the disease pathogenesis. Twenty-eight patients and 22 normal volunteers were studied; tears were obtained with capillary tubes. T helper/T suppressor ratios and the percentages of HLA DR+, CD23+, and CD3+ cells were significantly higher in patients than in controls. This study provides support for the hypothesis that chronic allergic conjunctivitis results from T lymphocyte-related immunological reactions.
authors.affiliation: Ophthalmology Department, School of Medicine, Black Sea Technical University, Trabzon, Turkey.
authors.forename: A M
authors.initials: AM
authors.lastname: Avunduk
authors.forename: M C
authors.initials: MC
authors.lastname: Avunduk
authors.forename: Y S
authors.initials: YS
authors.lastname: Dayioglu
authors.forename: K
authors.initials: K
authors.lastname: Centinkaya
mesh_terms: D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D003233:Conjunctivitis, Allergic / Q000276:immunology*; D005260:Female; D005434:Flow Cytometry; D006684:HLA-DR Antigens / Q000032:analysis; D006801:Humans; D008297:Male; D017455:Receptors, IgE / Q000032:analysis; D013601:T-Lymphocytes / Q000473:pathology; D013666:Tears / Q000737:chemistry* / Q000166:cytology
chemical_list: D006684:HLA-DR Antigens; D017455:Receptors, IgE