title: Pulmonary embolism associated with use of bone cement during hip arthroplasty.
abstract: Main circulatory (heart frequency, HF, intra-artery pressure, AP ECG) and respiratory (arterial oxyhemoglobin saturation SaO2, end-tidal CO2) arterial gas-analysis (HGA) parameters were recorded continually during cemented hip arthroplasty in 70 consecutive non-selected patients. The use of cement did not cause any change in the parameters obtained in 21 of the cases, reduction in arterial oxygen pressure (PaO2) ranging from 11% to 38% was observed in 44 cases, associated with simultaneous reduction in ETCO2 in 11 cases. The reduction in ETCO2 was an isolated finding in 5 of the patients. AP decreased by more than 10% in only 2 cases and there was arrhythmia in another 2 cases. These findings are strongly suggestive of pulmonary embolism encouraging the hypothesis of gas embolism previously suggested by other authors. In patients with little coronary or pulmonary reserve use of cement means an increased risk of severe hemodynamic complications.
authors.affiliation: II Servizio di Anestesia e Rianimazione, Istituti Ortopedici Rizzoli, Bologna.
authors.forename: G
authors.initials: G
authors.lastname: Fabbri
authors.forename: S
authors.initials: S
authors.lastname: Perin
authors.forename: A
authors.initials: A
authors.lastname: Colì
authors.forename: S
authors.initials: S
authors.lastname: Lari
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001843:Bone Cements / Q000009:adverse effects; D002245:Carbon Dioxide / Q000097:blood; D004618:Embolism, Air / Q000097:blood / Q000209:etiology; D005260:Female; D006439:Hemodynamics; D006622:Hip Prosthesis; D006801:Humans; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D011655:Pulmonary Embolism / Q000097:blood / Q000209:etiology*; D012307:Risk Factors
chemical_list: D001843:Bone Cements; D002245:Carbon Dioxide; D010100:Oxygen