title: Genetic relationships of Asians and Northern Europeans, revealed by Y-chromosomal DNA analysis.
abstract: We have identified a new T-->C transition on the human Y chromosome. C-allele chromosomes have been found only in a subset of the populations from Asia and northern Europe and reach their highest frequencies in Yakut, Buryats, and Finns. Examination of the microsatellite haplotypes of the C-allele chromosomes suggests that the mutation occurred recently in Asia. The Y chromosome thus provides both information about population relationships in Asia and evidence for a substantial paternal genetic contribution of Asians to northern European populations such as the Finns.
authors.affiliation: Department of Biochemistry, University of Oxford, United Kingdom.
authors.forename: T
authors.initials: T
authors.lastname: Zerjal
authors.forename: B
authors.initials: B
authors.lastname: Dashnyam
authors.forename: A
authors.initials: A
authors.lastname: Pandya
authors.forename: M
authors.initials: M
authors.lastname: Kayser
authors.forename: L
authors.initials: L
authors.lastname: Roewer
authors.forename: F R
authors.initials: FR
authors.lastname: Santos
authors.forename: W
authors.initials: W
authors.lastname: Schiefenhövel
authors.forename: N
authors.initials: N
authors.lastname: Fretwell
authors.forename: M A
authors.initials: MA
authors.lastname: Jobling
authors.forename: S
authors.initials: S
authors.lastname: Harihara
authors.forename: K
authors.initials: K
authors.lastname: Shimizu
authors.forename: D
authors.initials: D
authors.lastname: Semjidmaa
authors.forename: A
authors.initials: A
authors.lastname: Sajantila
authors.forename: P
authors.initials: P
authors.lastname: Salo
authors.forename: M H
authors.initials: MH
authors.lastname: Crawford
authors.forename: E K
authors.initials: EK
authors.lastname: Ginter
authors.forename: O V
authors.initials: OV
authors.lastname: Evgrafov
authors.forename: C
authors.initials: C
authors.lastname: Tyler-Smith
mesh_terms: D000818:Animals; D001208:Asia; D044466:Asian People / Q000235:genetics*; D001483:Base Sequence; D005075:Biological Evolution; D005060:Europe; D005787:Gene Frequency; D005819:Genetic Markers; D005843:Geography; D006239:Haplotypes; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D007802:Language; D008297:Male; D018895:Microsatellite Repeats; D008969:Molecular Sequence Data; D017354:Point Mutation; D044465:White People / Q000235:genetics*; D014998:Y Chromosome / Q000235:genetics*
chemical_list: D005819:Genetic Markers