title: [Experimental study of the effect of formaldehyde during embryogenesis on the activity of rat liver enzyme systems in ontogenesis].
abstract: The pregnant rats were treated with formaldehyde (0.5 mg/kg daily per os) during whole period of pregnancy. The activity of cytochrome-c-oxidase, malate dehydrogenase, nucleotidase, glucose-6-phosphatase, beta-glucuronidase, N-acetyl-beta-glucosaminidase, beta-galactosidase, H(+)-ATPase, glutamate dehydrogenase, NAD- and NADP-isocitrate dehydrogenase, fructose-bisphosphate aldolase, glucose-6-phosphate dehydrogenase and content of protein in liver celts of offsprings (newborns, 2 weeks age and 2 months age) were studied. It was shown differences in development enzyme systems of control and experimental animals during ontogenesis.
authors.forename: L F
authors.initials: LF
authors.lastname: Astakhova
authors.forename: L Kh
authors.initials: LKh
authors.lastname: Mukhambetova
authors.forename: Z I
authors.initials: ZI
authors.lastname: Koganova
authors.forename: S I
authors.initials: SI
authors.lastname: Dolinskaia
authors.forename: V I
authors.initials: VI
authors.lastname: Kazachkov
authors.forename: V S
authors.initials: VS
authors.lastname: Zhurkov
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development* / Q000378:metabolism; D005314:Embryonic and Fetal Development / Q000187:drug effects*; D004734:Energy Metabolism / Q000187:drug effects; D005260:Female; D005557:Formaldehyde / Q000633:toxicity*; D008099:Liver / Q000187:drug effects / Q000196:embryology / Q000201:enzymology*; D008297:Male; D011247:Pregnancy; D051381:Rats
chemical_list: D005557:Formaldehyde
vernacular_title: Eksperimental'noe izuchenie vozdeĭstviia formal'degida v period émbriogeneza na aktivnost' fermentnykh sistem pecheni krys v ontogeneze.