Synaptic plasticity: a role for nitric oxide in LTP.
Nitric oxide is back in the spotlight with a new series of studies showing that it plays an important role in long-term potentiation, the best-studied type of synaptic plasticity in the central nervous system thought likely to play an important role in learning and memory.
Huang
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Molecular Neurobiology Laboratory, Howard Hughes Medical Institute, The Salk Institute, 10010 North Torrey Pines Road, La Jolla, California 92037, USA. ehuang@axp1.salk.edu
D000818:Animals; D002118:Calcium / Q000502:physiology; D002147:Calmodulin / Q000502:physiology; D006801:Humans; D007858:Learning / Q000502:physiology; D017774:Long-Term Potentiation / Q000502:physiology*; D008568:Memory / Q000502:physiology; D051379:Mice; D018345:Mice, Knockout; D008959:Models, Neurological; D009419:Nerve Tissue Proteins / Q000502:physiology; D009569:Nitric Oxide / Q000502:physiology*; D019001:Nitric Oxide Synthase / Q000502:physiology; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology; D013569:Synapses / Q000502:physiology
D002147:Calmodulin; D009419:Nerve Tissue Proteins; D016194:Receptors, N-Methyl-D-Aspartate; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; D002118:Calcium