title: Haematological reference ranges for schoolchildren.
abstract: There are few reports of reference ranges for haematological values in school age children and most studies extend over a small age range or have excluded a considerable proportion of the study population in an effort to omit those with haemoglobinopathies or anaemia. Blood samples from 2135 children aged 4-19 years, from randomly selected schools, were analysed by automated counter. Reference ranges for red cell, white cell and platelet indices are provided from the results. Median haemoglobin and red blood cell count values for girls and boys rose together with increasing age, up to 12 years, but then diverged. Girls had a higher platelet count than boys. Mean platelet volume rose with age and was inversely related to the platelet count. Plateletcrit fell with age but in girls there was a peri-pubertal peak. Total leucocyte count fell with age. The upper limits for total leucocyte count in this study are approximately 2 x 10(9) lower than those quoted in modern haematology textbooks. Lymphocyte, eosinophil and basophil counts fell with age with little difference between the sexes. Neutrophil and monocyte counts were similar for younger girls and boys but diverged in the older children with the older girls having higher values than boys.
authors.affiliation: Department of Paediatrics, Trinity College Dublin, Ireland.
authors.forename: M R
authors.initials: MR
authors.lastname: Taylor
authors.forename: C V
authors.initials: CV
authors.lastname: Holland
authors.forename: R
authors.initials: R
authors.lastname: Spencer
authors.forename: J F
authors.initials: JF
authors.lastname: Jackson
authors.forename: G I
authors.initials: GI
authors.lastname: O'Connor
authors.forename: J R
authors.initials: JR
authors.lastname: O'Donnell
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001772:Blood Cell Count; D002648:Child; D002675:Child, Preschool; D004909:Erythrocyte Indices; D005260:Female; D006403:Hematologic Tests / Q000592:standards / Q000706:statistics & numerical data; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D010976:Platelet Count; D012016:Reference Values; D012737:Sex Factors