The Rhesus D-negative phenotype is an independent predictor of poor prognosis in curatively (RO) resected gastric cancer patients.
Among gastric cancer patients, the Rhesus D-negative phenotype correlated with increased tumour recurrence [all patients, n = 83, P = 0.026; curatively (R0) resected patients, n = 51, P = 0.093] and reduced overall survival time (all patients, log-rank P = 0.0028; R0 patients, log-rank P = 0.0003) and was identified in multivariate analysis as the most important independent prognostic marker in the R0 patient group (relative risk 9.1, P = 0.0013).
Mayer
B
B
Department of Surgery, University of Munich, Germany.
Schraut
W
W
Funke
I
I
Jauch
K W
KW
Mempel
W
W
Johnson
J P
JP
Schildberg
F W
FW
D000368:Aged; D018450:Disease Progression; D005260:Female; D006801:Humans; D016130:Immunophenotyping; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local; D011379:Prognosis; D012204:Rh-Hr Blood-Group System / Q000276:immunology*; D013274:Stomach Neoplasms / Q000097:blood* / Q000401:mortality / Q000601:surgery; D016019:Survival Analysis
D012204:Rh-Hr Blood-Group System