[The effect of 2-methyl-4-amino-6-hydroxypyrimidine on delayed hypersensitivity].
The effect of the immunomodulator 2-methyl-4-amino-6-oxypyrimidine (MAOP)on delayed hypersensitivity was studied in experiments on mongrel mice and in C57Bl and CBA mice. The effect of MAOP and that of oxymethyluracil on delayed hypersensitivity to sheep erythrocytes and dinitrofluorobenzene were compared. Immunosuppression of mice was induced by hydrocortisone in a dose of 50 mg/kg.
Ismagilova
A F
AF
Zarudiĭ
F S
FS
Davydova
V A
VA
Lazareva
D N
DN
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D004139:Dinitrofluorobenzene; D004353:Drug Evaluation, Preclinical; D006968:Hypersensitivity, Delayed / Q000188:drug therapy / Q000209:etiology / Q000276:immunology / Q000517:prevention & control*; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D010432:Pentoxyl / Q000031:analogs & derivatives / Q000627:therapeutic use; D011743:Pyrimidines / Q000627:therapeutic use*; D050378:T-Lymphocytes, Regulatory / Q000187:drug effects / Q000276:immunology
C096002:2-methyl-6-amino-6-hydroxypyrimidine; D000276:Adjuvants, Immunologic; D011743:Pyrimidines; C008055:5-hydroxymethyluracil; D010432:Pentoxyl; D004139:Dinitrofluorobenzene
Vliianie 2-metil-4-amino-6-oksipirimidina na giperchuvstvitel'nost' zamedlennogo tipa.