title: Feto-maternal bleeding following coelocentesis.
abstract: The potential risk of feto-maternal haemorrhage following coelocentesis was examined in 17 singleton pregnancies at 6-11 weeks of gestation by measuring maternal serum concentration of alpha fetoprotein (AFP) before and 1 and 10 min after the procedure. There was no significant difference between the maternal serum AFP concentration before coelocentesis (median 7.5, range 4.5-21.5 IU) compared to the values at 1 min (median 8.6, range 3.9-17.8; Z = -0.504, P = 0.614), and 10 min (median 7.5, range 5.7-20.6; Z = -0.432, P = 0.666) after the procedure. These findings demonstrate that coelocentesis is not associated with significant feto-maternal haemorrhage.
authors.affiliation: Department of Obstetrics and Gynaecology, Ioannina University Hospital, Greece.
authors.forename: G
authors.initials: G
authors.lastname: Makrydimas
authors.forename: D
authors.initials: D
authors.lastname: Lolis
authors.forename: I
authors.initials: I
authors.lastname: Georgiou
authors.forename: I
authors.initials: I
authors.lastname: Navrozoglou
authors.forename: K H
authors.initials: KH
authors.lastname: Nicolaides
mesh_terms: D005260:Female; D005331:Fetomaternal Transfusion / Q000209:etiology*; D006801:Humans; D011237:Predictive Value of Tests; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D011296:Prenatal Diagnosis / Q000009:adverse effects* / Q000379:methods; D012307:Risk Factors; D000509:alpha-Fetoproteins / Q000032:analysis*
chemical_list: D000509:alpha-Fetoproteins