title: Dihydroisocoumarins from fungi: isolation, structure elucidation, circular dichroism and biological activity.
abstract: Five known and three new dihydroisocoumarins were isolated from different fungi. The new isocoumarins are 5-chloro-6-hydroxymellein, 5-chloro-4,6-dihydroxymellein and 5,6-dihydroxymellein. The absolute configuration of these secondary metabolites was confirmed by CD measurements and in two cases by X-ray structure analysis.
authors.affiliation: Fachbereich Chemie und Chemietechnik der Universität-GH Paderborn, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Krohn
authors.forename: R
authors.initials: R
authors.lastname: Bahramsari
authors.forename: U
authors.initials: U
authors.lastname: Flörke
authors.forename: K
authors.initials: K
authors.lastname: Ludewig
authors.forename: C
authors.initials: C
authors.lastname: Kliche-Spory
authors.forename: A
authors.initials: A
authors.lastname: Michel
authors.forename: H J
authors.initials: HJ
authors.lastname: Aust
authors.forename: S
authors.initials: S
authors.lastname: Draeger
authors.forename: B
authors.initials: B
authors.lastname: Schulz
authors.forename: S
authors.initials: S
authors.lastname: Antus
mesh_terms: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D001410:Bacillus megaterium / Q000187:drug effects; D002708:Chlorella / Q000187:drug effects; D002942:Circular Dichroism; D003374:Coumarins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology*; D018360:Crystallography, X-Ray; D004926:Escherichia coli / Q000187:drug effects; D005658:Fungi / Q000737:chemistry* / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010944:Plants / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D003374:Coumarins