title: Two specific and simple methods for genotyping of the paraoxonase/arylesterase A/B polymorphism.
abstract: We developed an amplification refractory mutation system (ARMS) and mutagenically separated PCR (MS-PCR) assays for genotyping of the paraoxonase/arylesterase (PONA) A/B polymorphism as practical, reliable, and more economic alternatives to the conventional restriction fragment length polymorphism (RFLP) technique for detection of this mutation.
authors.affiliation: Departmeng of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
authors.forename: C
authors.initials: C
authors.lastname: Schmitz
authors.forename: K
authors.initials: K
authors.lastname: Lindpaintner
mesh_terms: D043303:Aryldialkylphosphatase; D004950:Esterases / Q000235:genetics*; D005838:Genotype; D006801:Humans; D008722:Methods; D017354:Point Mutation; D016133:Polymerase Chain Reaction / Q000379:methods; D011110:Polymorphism, Genetic
chemical_list: D004950:Esterases; D043303:Aryldialkylphosphatase