Severe thrombosis after chemotherapy for metastatic choriocarcinoma of the testis maintaining complete remission for a long period.
We report the favourable outcome of a patient who suffered from severe arterial and venous thrombosis during chemotherapy for testicular pure choriocarcinoma. An increased paraneoplastic stimulus of HCG secondary to the marker surge phenomenon is suggested as responsible for transient hypercoagulability and subsequent thromboembolism.
Lepidini
G
G
Oncology and Radiotherapy Department, S. Camillo Hospital, Rome, Italy.
Biancari
F
F
D'Andrea
V
V
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D001780:Blood Coagulation Tests; D017024:Chemotherapy, Adjuvant; D002822:Choriocarcinoma / Q000097:blood / Q000188:drug therapy*; D006063:Chorionic Gonadotropin; D002945:Cisplatin / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D008297:Male; D009919:Orchiectomy; D010257:Paraneoplastic Syndromes / Q000097:blood / Q000139:chemically induced*; D013736:Testicular Neoplasms / Q000097:blood / Q000188:drug therapy*; D013923:Thromboembolism / Q000097:blood / Q000139:chemically induced*
D006063:Chorionic Gonadotropin; D002945:Cisplatin