Use of sucrose as a treatment for infant colic.
OBJECTIVE
To examine if sucrose has an analgesic effect on infant colic.


METHODS
Nineteen infants with typical infant colic were given 2 ml of 12% sucrose or distilled water when crying, in a double blind double crossover study. The effect was measured by parents' score.


RESULTS
Twelve improved specifically on sucrose and one on placebo (p < 0.01). Five showed a non-specific improvement.


CONCLUSIONS
Sucrose has a significant ameliorating effect on infant colic.
Markestad
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Department of Paediatrics, University of Bergen, Norway.
D000284:Administration, Oral; D000700:Analgesics / Q000008:administration & dosage*; D003085:Colic / Q000188:drug therapy*; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D013395:Sucrose / Q000008:administration & dosage*
D000700:Analgesics; D013395:Sucrose