title: Effect of the type of dietary fat on cholesterolemia in rabbits fed brewer's yeast.
abstract: To determine the effects of the kind of dietary fat on cholesterolemia in rabbits fed with brewer's yeast, diets based on soybean protein isolate or on a mixture of soybean protein isolate and brewer's yeast (1:1) were used. They were combined with corn oil and coconut oil in four balanced, cholesterol-free diets. Twenty four rabbits were fed with 79 grams of diet per day during 3 weeks. After 14 hours of fasting on the 22nd day, blood samples from the marginal ear vein were collected, animals were sacrificed and their livers dissected. There were no significant differences in the final plasma concentrations of the total lipids, triglycerides, total cholesterol, high density lipoprotein-cholesterol, and (low density lipoprotein + very low density lipoprotein)-cholesterol, even though groups fed yeast presented the highest values. Liver lipids were not affected by dietary treatment. However, when comparing the final plasma cholesterol with the initial cholesterol, a significant increase in the groups which consumed yeast with com oil (48 mg/dL) and coconut oil (91 mg/dL) was observed in comparison with the groups which only consumed soybean protein with corn oil (21 mg/dL) and coconut oil (36 mg/dL). The two-way variance analysis of these data showed that there was no fat-protein interaction and the hypercholesterolemic effects observed were associated with brewer's yeast consumption.
authors.affiliation: Simón Bolívar University, Cellular Biology Department, Caracas, Venezuela.
authors.forename: N
authors.initials: N
authors.lastname: Millán
authors.forename: J
authors.initials: J
authors.lastname: De Abreu
mesh_terms: D000704:Analysis of Variance; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002784:Cholesterol / Q000032:analysis / Q000097:blood*; D003059:Cocos; D003314:Corn Oil; D004032:Diet; D004041:Dietary Fats / Q000009:adverse effects*; D008055:Lipids / Q000032:analysis; D008099:Liver / Q000737:chemistry; D010938:Plant Oils; D011817:Rabbits; D012441:Saccharomyces cerevisiae; D030262:Soybean Proteins; D014280:Triglycerides / Q000032:analysis
chemical_list: D004041:Dietary Fats; D008055:Lipids; D010938:Plant Oils; D030262:Soybean Proteins; D014280:Triglycerides; D003314:Corn Oil; D002784:Cholesterol