[The role of the opioid system in body adaptation and protection of the heart in stress].
Literary data and the results of our own studies on the role of opioid neuropeptides in the adaptation of organism and heart protection under the action of extreme factors were analysed. The data on the cardioprotective, antiarrhythmic, neurohumoral, antistressor effects of enkephalins are grown. Possible mechanisms and the role of various populations of opiate receptors in the realisation of opioid peptides' adaptation effects are studied. The key role of endogenous opiate system in the mechanism of cardioprotective effects of natural adaptogens and adaptation is established.
Lishmanov
Iu B
IuB
Maslov
L N
LN
Lasukova
T V
TV
D000222:Adaptation, Physiological; D000818:Animals; D006321:Heart / Q000502:physiology*; D008024:Ligands; D009712:Nucleotides, Cyclic / Q000502:physiology; D018847:Opioid Peptides / Q000502:physiology; D011453:Prostaglandins / Q000502:physiology; D011957:Receptors, Opioid / Q000502:physiology*; D013312:Stress, Physiological / Q000503:physiopathology*
D008024:Ligands; D009712:Nucleotides, Cyclic; D018847:Opioid Peptides; D011453:Prostaglandins; D011957:Receptors, Opioid
Rol' opioidnoĭ sistemy v adaptatsii organizma i zashchite serdtsa pri stresse.