[Craniopharyngioma in childhood. Significance of the extent of surgical resection and adjuvant megavoltage irradiation for event: free survival].
A series of 81 children with craniopharyngiomas is presented. All patients were operated on between 1981 and 1992. According to the applied treatment the presented group was divided into three distinct categories. 28 patients underwent what was considered by the surgeon to be total excision of their tumour, 27 bad partial excision, in the rest 26 children partial excision of the tumour was followed by local rtgtherapy. The impact on the outcome, the statistically estimated probability of event-free survival, following different type of applied treatment was the main aim of this study. The 5- and 10-year actuarial recurrence free survival rate were 78% and 52% respectively, for total removal group, versus 46% and 28% for partial removal, and 49% and 18% for partial removal followed by megavoltage irradiation. The study show a statistically significant advantage for radial surgical removal of childhood craniopharyngioma in event free survival. It is emphasized that total resection using modern diagnostic and surgical methods is the mainstay for childhood carniopharyngioma. Nearly 87% of pediatric craniopharyngiomas can be totally resected.
Roszkowski
M
M
Oddziału Neurochirurgii Dzieciecej IPCZD w Warszawie.
Barszcz
S
S
Dramińska
D
D
Kościesza
A
A
Grajkowska
W
W
Gardas-Skowrońska
A
A
D000293:Adolescent; D001921:Brain / Q000473:pathology / Q000528:radiation effects / Q000601:surgery; D001932:Brain Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D003397:Craniopharyngioma / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies; D015996:Survival Rate
Czaszkogardlaki wieku dzieciecego. Wpływ rozległości resekcji chirurgicznej oraz radioterapii na czas przezycia wolny od wznowy guza.