Tissue reaction to three subcutaneously implanted local hemostatic agents.
Soft tissue response to three subcutaneously implanted local hemostatic agents; oxidised regenerated cellulose (Surgicel), gelatin sponge (Spongostan) and collagen sponge (Hemostagen) were evaluated histopathologically 7, 14, 21, 30 and 45 days following their implantation in rats. The results showed that all materials were well tolerated by soft tissues. These materials neither seemed to impair nor contribute to wound healing.
Alpaslan
C
C
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ankara, Turkey.
Alpaslan
G H
GH
Oygur
T
T
D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology*; D002196:Capillaries / Q000473:pathology; D002483:Cellulose, Oxidized / Q000494:pharmacology; D003094:Collagen / Q000494:pharmacology; D003238:Connective Tissue / Q000473:pathology; D005260:Female; D005339:Fibrin Foam / Q000494:pharmacology; D005347:Fibroblasts / Q000473:pathology; D006097:Granulation Tissue / Q000473:pathology; D006490:Hemostatics / Q000494:pharmacology*; D008297:Male; D009504:Neutrophils / Q000473:pathology; D051381:Rats; D012867:Skin / Q000098:blood supply / Q000473:pathology*; D013530:Surgical Wound Infection / Q000473:pathology; D014945:Wound Healing
D001672:Biocompatible Materials; D002483:Cellulose, Oxidized; D005339:Fibrin Foam; D006490:Hemostatics; C013695:Surgicel; D003094:Collagen