Ultrastructural relationships of the pro-opiomelanocortin axons with the serotoninergic neurons in the dorsal raphe nucleus of the rat.
The relationships of the corticotropin-like intermediate lobe peptide (CLIP)/ACTH-immunoreactive axons with the serotoninergic and non-serotoninergic neurons in the dorsal raphe nucleus of the rat were examined by means of a double label immunocytochemical method. It is suggested that the rare contacts established by the CLIP/ACTH-immunoreactive fibers with serotoninergic neurons (cell bodies and dendrites) are not under a synaptic from. In contrast, the contacts with non-serotoninergic neurons were predominantly formed with dendrites and showed a substantial number of synapses.
Léger
L
L
Département de Médecine Expérimentale, Faculté de Médecine, INSERMU 52, CNRS ERS 5645, Université Claude Bernard, Lyon, France. leger@ura1195-6.univ-lyonl.fr
Zheng
Z
Z
Bonnet
C
C
Cespuglio
R
R
D000324:Adrenocorticotropic Hormone / Q000032:analysis; D000818:Animals; D001369:Axons / Q000737:chemistry* / Q000648:ultrastructure; D053497:Corticotropin-Like Intermediate Lobe Peptide; D003712:Dendrites / Q000737:chemistry; D008297:Male; D009474:Neurons / Q000737:chemistry* / Q000648:ultrastructure; D010446:Peptide Fragments / Q000032:analysis; D011333:Pro-Opiomelanocortin / Q000032:analysis*; D011903:Raphe Nuclei / Q000737:chemistry* / Q000648:ultrastructure; D051381:Rats; D012701:Serotonin / Q000032:analysis*; D013569:Synapses / Q000737:chemistry
D010446:Peptide Fragments; D012701:Serotonin; D053497:Corticotropin-Like Intermediate Lobe Peptide; D011333:Pro-Opiomelanocortin; D000324:Adrenocorticotropic Hormone