Surgical tactics in the treatment of malignant renal tumors in childhood.
The authors report the treatment results of 89 children with renal tumors (excluding carcinoma) seen from 1988 to 1992, 71 (79.8%) with favorable-histology Wilms' tumor (survival 86%) and 18 (20.2%) with unfavorable histology, including anaplastic nephroblastoma, clear-cell sarcoma, and rhabdoid tumor (survival 61%). Preoperative chemotherapy (ChT) was given to 46 patients (survival 84%); none was given to 43 with either tumors in the 1st year of life, massive hematuria, or tumor growth during ChT (survival 78%). There were 3 tumor ruptures in the latter group compared to 1 in the former group.
Pýcha
K
K
Department of Pediatric Surgery, Motol Children's Hospital, 2nd Medical School, Charles' University in Prague, 15018 Prague 5, Czech Republic.
Snajdauf
J
J
Koutecký
J
J
Kodet
R
R
Zítková
M
M
D017024:Chemotherapy, Adjuvant; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007668:Kidney / Q000473:pathology; D007680:Kidney Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008297:Male; D009367:Neoplasm Staging; D009392:Nephrectomy; D018335:Rhabdoid Tumor / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018227:Sarcoma, Clear Cell / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D015996:Survival Rate; D009396:Wilms Tumor / Q000188:drug therapy / Q000401:mortality / Q000473:pathology / Q000601:surgery*