Extraction and purification of effective antimicrobial constituents of Terminalia chebula RETS. against methicillin-resistant Staphylococcus aureus.
Examination of the EtOH extract of the fruiting bodies of Terminalia chebula RETZ. led to the isolation of two potent antimicrobial substances against even methicillin-resistant strains of Staphylococcus aureus. On the basis of spectroscopic evidence, the two isolates have been identified as gallic acid and its ethyl ester.
Sato
Y
Y
Faculty of Pharmaceutical Sciences, University of Tokushima, Japan.
Oketani
H
H
Singyouchi
K
K
Ohtsubo
T
T
Kihara
M
M
Shibata
H
H
Higuti
T
T
D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D005707:Gallic Acid / Q000031:analogs & derivatives / Q000302:isolation & purification / Q000494:pharmacology; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D010946:Plants, Medicinal / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D010936:Plant Extracts; C048734:ethyl gallate; D005707:Gallic Acid