title: Histone acetylation: chromatin in action.
abstract: Histone acetylation acts as a landmark and determinant for chromatin function. Active roles in the transcription and assembly of chromatin have been discovered for histone acetyltransferases and deacetylases. This review highlights these roles and discusses their significance for the maintenance of cell differentiation.
authors.affiliation: Laboratory of Molecular Embryology, National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892-5431, USA. awlme@helix.nih.gov
authors.forename: P A
authors.initials: PA
authors.lastname: Wade
authors.forename: D
authors.initials: D
authors.lastname: Pruss
authors.forename: A P
authors.initials: AP
authors.lastname: Wolffe
mesh_terms: D000107:Acetylation; D000123:Acetyltransferases / Q000235:genetics / Q000378:metabolism; D002453:Cell Cycle / Q000235:genetics*; D002454:Cell Differentiation / Q000235:genetics; D002843:Chromatin / Q000235:genetics / Q000378:metabolism*; D051548:Histone Acetyltransferases; D006657:Histones / Q000235:genetics / Q000378:metabolism*; D008938:Mitosis; D029701:Saccharomyces cerevisiae Proteins; D014158:Transcription, Genetic
chemical_list: D002843:Chromatin; D006657:Histones; D029701:Saccharomyces cerevisiae Proteins; D000123:Acetyltransferases; D051548:Histone Acetyltransferases