title: Modality-specific organization for cutaneous and proprioceptive sense in human primary sensory cortex studied by chronic epicortical recording.
abstract: Modality specificity of human primary somatosensory cortex was studied by recording somatosensory evoked potentials (SEPs) from subdural electrodes in a patient with intractable focal motor seizure. A newly developed device was used for selectively activating proprioception. The spatial and temporal distributions of proprioception-related SEPs elicited by brisk passive flexion movement at the proximal interphalangeal (PIP) joint of the middle finger (4 degrees in 25 ms) were quite different from those to cutaneous sense evoked by electric stimulation of the digital nerve at the same site. It was for the first time demonstrated that proprioception-related SEPs following passive finger movement do not originate in area 3b, which was clearly activated by cutaneous stimulation, and that other sites at the sensorimotor cortex such as areas 2, 3a and 4 possibly contribute to the cortical processing of proprioception.
authors.affiliation: Department of Brain Pathophysiology, Kyoto University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Mima
authors.forename: A
authors.initials: A
authors.lastname: Ikeda
authors.forename: K
authors.initials: K
authors.lastname: Terada
authors.forename: S
authors.initials: S
authors.lastname: Yazawa
authors.forename: N
authors.initials: N
authors.lastname: Mikuni
authors.forename: T
authors.initials: T
authors.lastname: Kunieda
authors.forename: W
authors.initials: W
authors.lastname: Taki
authors.forename: J
authors.initials: J
authors.lastname: Kimura
authors.forename: H
authors.initials: H
authors.lastname: Shibasaki
mesh_terms: D000328:Adult; D004569:Electroencephalography; D004827:Epilepsy / Q000503:physiopathology*; D005073:Evoked Potentials, Somatosensory / Q000502:physiology*; D006801:Humans; D008297:Male; D011434:Proprioception / Q000502:physiology*