title: Synthesis and biological activity studies of 1,3,4-thiadiazolo[2,3-c]-as-triazines.
abstract: Several new 1,3,4-thiadiazolo[2,3-c]-as-triazines were synthesized by the reaction of 6-substituted-4-amino-3-mercapto-1,3,4-triazon-5 (4H)-ones with appropriate aromatic and heterocyclic carboxylic acids in the presence of phosphorus oxychloride. The structures of the newly synthesized compounds were established on the basis of analytical, IR, NMR and mass spectral data. Some selected compounds from this series were subjected to both antimicrobial and pharmacological studies.
authors.affiliation: Department of Studies in Chemistry, Mangalore University, India.
authors.forename: B
authors.initials: B
authors.lastname: Kalluraya
authors.forename: S
authors.initials: S
authors.lastname: Sreenivasa
authors.forename: D
authors.initials: D
authors.lastname: Banji
mesh_terms: D000818:Animals; D000871:Anthelmintics / Q000138:chemical synthesis / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009835:Oligochaeta; D051381:Rats; D013830:Thiadiazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D014227:Triazines / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000871:Anthelmintics; D000890:Anti-Infective Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D013830:Thiadiazoles; D014227:Triazines