[The effect of uropolinum on phagocytosis of sperm by cultured peritoneal macrophages in rats].
Peritoneal macrophages and sperm were cultured with and without uropolinum. The macrophages were isolated from female rat peritoneal cavities and sperm from male rat cauda epididymis. Sperm phagocytosis index was estimated in cultures with increasing concentrations of uropolinum. Authors concluded that uropolinum inhibited sperm phagocytosis by peritoneal macrophages. The results were verified by electron microscopic examinations. The latter additionally revealed that uropolinum enhanced an adhesion between the macrophages.
Wenda-Rózewicka
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Katedry i Zakładu Histologii i Embriologii Pomorskiej Akademii Medycznej w Szczecinie.
Mikulska
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Kurzawa
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D000818:Animals; D002448:Cell Adhesion / Q000187:drug effects; D002478:Cells, Cultured; D003287:Contrast Media / Q000494:pharmacology*; D003973:Diatrizoate / Q000494:pharmacology*; D003974:Diatrizoate Meglumine / Q000494:pharmacology*; D004338:Drug Combinations; D005260:Female; D017737:Macrophages, Peritoneal / Q000187:drug effects* / Q000276:immunology / Q000648:ultrastructure; D008297:Male; D008854:Microscopy, Electron; D010587:Phagocytosis / Q000187:drug effects* / Q000276:immunology; D051381:Rats; D013094:Spermatozoa / Q000276:immunology* / Q000648:ultrastructure
D003287:Contrast Media; D004338:Drug Combinations; D003973:Diatrizoate; D003974:Diatrizoate Meglumine; C027278:urovision
Wpływ uropoliny na fagocytoze plemników w hodowlach makrofagów otrzewnowych u szczurów.