title: Radionuclide imaging of abomasal emptying in sheep.
abstract: A liquid radionuclide tracer was administered to nine sheep in order to visualise the abomasum with a gamma camera computer system. The aim was to develop a method of studying gastric emptying, with minimal surgical intervention. Oral administration of the tracer gave good images of the whole complex stomach, but quantifying abomasal emptying was not possible because of the superimposition of the stomach compartments. When the reticular groove reflex was stimulated with oral copper sulphate the radionuclide bypassed the reticulorumen, allowing quantitative analysis of abomasal activity. However, the repeatability of the reflex activation was low. Radionuclide administered directly into the abomasum produced good images of abomasal outflow and provided digital data which were analysed quantitatively. A wide range of emptying rates was observed, generally with a stepped pattern.
authors.affiliation: Department of Veterinary Preclinical Sciences, University of Liverpool.
authors.forename: T
authors.initials: T
authors.lastname: Nicholson
authors.forename: H R
authors.initials: HR
authors.lastname: Stockdale
authors.forename: M
authors.initials: M
authors.lastname: Critchley
authors.forename: J S
authors.initials: JS
authors.lastname: Grime
authors.forename: R S
authors.initials: RS
authors.lastname: Jones
authors.forename: P
authors.initials: P
authors.lastname: Maltby
mesh_terms: D000018:Abomasum / Q000000981:diagnostic imaging* / Q000502:physiology*; D000818:Animals; D005746:Gastric Emptying / Q000502:physiology*; D011877:Radionuclide Imaging; D012417:Rumen / Q000502:physiology; D012756:Sheep / Q000502:physiology*; D016284:Technetium Tc 99m Pentetate
chemical_list: D016284:Technetium Tc 99m Pentetate