[Acylation of 3beta-(2-hydroxyethoxy)cholest-5-ene in the presence of lecithin:cholesterol acyltransferase from blood plasma].
3 beta-(2-Hydroxyethoxy)cholest-5-ene in the composition of the micellar complexes with apolipoprotein A1 and palmitoyloleoylphosphatidylcholine was acylated in the presence of lecithin-cholesterol acyltransferase from human plasma. The initial rate of acylation was 6-8 times lower than the rate of cholesterol acylation under the same conditions. The presence of 3 beta-(2-hydroxyethoxy)cholest-5-ene did not affect the rate of the enzymic acylation of cholesterol.
Maliugin
A V
AV
Misharin
A Iu
AIu
D000215:Acylation; D016632:Apolipoprotein A-I / Q000378:metabolism; D002788:Cholesterol Esters / Q000378:metabolism; D006801:Humans; D006888:Hydroxycholesterols / Q000378:metabolism*; D008823:Micelles; D007862:Phosphatidylcholine-Sterol O-Acyltransferase / Q000097:blood*
D016632:Apolipoprotein A-I; D002788:Cholesterol Esters; D006888:Hydroxycholesterols; D008823:Micelles; D007862:Phosphatidylcholine-Sterol O-Acyltransferase
Atsilirovanie 3beta-(2-gidroksiétoksi)kholest-5-ena v prisutstvii letsitin:kholesterin-atsiltransferazy plazmy krovi.