title: Fine needle aspiration biopsy in hepatic Echinococcus multilocularis.
abstract: OBJECTIVE
  To determine the fine needle aspiration biopsy (FNAB) findings in hepatic Echinococcus multilocularis.
  
  
  METHODS
  FNAB and tru-cut liver needle biopsy were applied in 14 hepatic E multilocularis cases. Cytologic smears were stained with May-Grünwald-Giemsa and periodic acid-Schiff (PAS) stain. Tissue sections were stained with hematoxylin-eosin (HE) and PAS stain.
  
  
  RESULTS
  In tissue sections, homogeneous, thin, cystic structures of various dimensions strongly stained with PAS. Mucoid material was stained with PAS in the cystic structures. Wide, coagulative necrosis was observed in all cases. In some cases there were foreign body-type giant cells at the periphery of the lesion. In all the cytologic smears there were an intense necrotic ground, PAS-positive hyaline cuticular structures and mucoid globules; in some cases there were foreign body-type giant cells.
  
  
  CONCLUSIONS
  The above cytologic characteristics are basic diagnostic criteria for FNAB of E multilocularis.
authors.affiliation: Department of Pathology, School of Medicine, Atatürk University, Erzurum, Turkey.
authors.forename: M A
authors.initials: MA
authors.lastname: Ciftçioğlu
authors.forename: M I
authors.initials: MI
authors.lastname: Yildirgan
authors.forename: M N
authors.initials: MN
authors.lastname: Akçay
authors.forename: A
authors.initials: A
authors.lastname: Reis
authors.forename: M
authors.initials: M
authors.lastname: Safali
authors.forename: E
authors.initials: E
authors.lastname: Aktaş
mesh_terms: D001706:Biopsy / Q000379:methods*; D001707:Biopsy, Needle / Q000379:methods*; D004444:Echinococcosis, Hepatic / Q000473:pathology*; D006652:Histological Techniques; D006801:Humans