[Relation of spondylarthropathies and HLA-B27 antigen in patients from the state of Zulia, Venezuela].
HLA-B27 and associate antigens incidence were studied in 620 cases of seronegative spondiloarthropathies (SNS) and 262 controls of a Venezuelan mestizo population from Zulla state between 1985 and 1995. The incidence of HLA-B27 was 20.96% of all cases of SNS. It was increased in patients with ankilosing spondylitis (AS) 33.33% and Relter's syndrome (RS) 30%, but not in uveitis (Uv) 20% an psoriatic arthropathy (PsA) 0%. The incidence in the control group was 4.2%. This results are lower than the previous description in Venezuelan mestizo and caucasic population but are close to the incidence described in population of West Africa with important contribution to admixture of the occidental part of Venezuela.
Rivera
S
S
Universidad del Zulia, Facultad de Medicina, Maracaibo, Venezuela.
Hassanhi
M
M
Márquez
G
G
Fuenmayor
A
A
Monzón
J
J
Avila
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004198:Disease Susceptibility; D005260:Female; D005787:Gene Frequency; D015796:HLA-B27 Antigen / Q000032:analysis* / Q000235:genetics; D006801:Humans; D007199:Indians, South American / Q000235:genetics; D008297:Male; D008875:Middle Aged; D013166:Spondylitis / Q000453:epidemiology / Q000235:genetics*; D013167:Spondylitis, Ankylosing / Q000453:epidemiology / Q000235:genetics; D014687:Venezuela / Q000453:epidemiology; D044465:White People / Q000235:genetics
D015796:HLA-B27 Antigen
Estudio de la relación existente entre las espondiloartropatías y el antígeno HLA-B27 en pacientes del estado Zulia de Venezuela.