title: Kikuchi disease (histiocytic necrotizing lymphadenitis) in association with HTLV1.
abstract: We report a 25-year-old male with fever, generalized lymphadenopathy and an erythematosus maculo-papular eruption affecting face and upper body. A diagnosis of Kikuchi disease (necrotizing histiocytic lymphadenitis) was made on lymph node histology. The patient was found to be positive for the human T-cell leukaemia lymphoma virus (HTLV1). Kikuchi disease has been reported in association with infections such as Epstein-Barr virus (EBV), herpes (HHV6) and toxoplasmosis, but to our knowledge this is the first case of Kikuchi disease associated with HTLV1.
authors.affiliation: Dermatology Department, St. Helier Hospital, Carshalton, Surrey, U.K.
authors.forename: V
authors.initials: V
authors.lastname: Bataille
authors.forename: C C
authors.initials: CC
authors.lastname: Harland
authors.forename: J
authors.initials: J
authors.lastname: Behrens
authors.forename: M G
authors.initials: MG
authors.lastname: Cook
authors.forename: C A
authors.initials: CA
authors.lastname: Holden
mesh_terms: D000328:Adult; D015490:HTLV-I Infections / Q000150:complications* / Q000473:pathology; D015614:Histiocytosis / Q000473:pathology / Q000821:virology*; D006801:Humans; D008199:Lymphadenitis / Q000473:pathology / Q000821:virology*; D008297:Male