title: Giant glioependymal cyst resembling holoprosencephaly on prenatal ultrasound: case report and review of the literature.
abstract: We report the earliest in utero presentation of a 'giant' glioependymal cyst detected on routine prenatal ultrasound at 22 weeks estimated gestational age. The clinicopathologic features of these rare lesions are reviewed as well as previous reports of glioependymal cysts detected in utero. The effects of large intracranial cysts on neurodevelopment are discussed as well as the differential diagnosis of infantile intracranial cysts and therapeutic alternatives.
authors.affiliation: Department of Pathology, University of Virginia Health Sciences Center, Charlottesville 22908, USA.
authors.forename: T J
authors.initials: TJ
authors.lastname: Pelkey
authors.forename: J E
authors.initials: JE
authors.lastname: Ferguson
authors.forename: J C
authors.initials: JC
authors.lastname: Veille
authors.forename: S R
authors.initials: SR
authors.lastname: Alston
mesh_terms: D000328:Adult; D001927:Brain Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D003560:Cysts / Q000000981:diagnostic imaging* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D016142:Holoprosencephaly / Q000000981:diagnostic imaging*; D006801:Humans; D011247:Pregnancy; D016216:Ultrasonography, Prenatal