Efficacy of intracytoplasmic sperm injection (ICSI) treatment in the immunological infertile patients.
OBJECTIVE
To evaluate the efficacy of intracytoplasmic sperm injection (ICSI) treatment in the immunological infertile patients.


METHODS
The subjects were 60 cycles of 44 immunological infertile patients and these clinical data were analysed, retrospectively. They were classified into female and male immunological infertility group and were treated with conventional IVF, ICSI, and half-ICSI.


RESULTS
The fertilization rate of ICSI (60.3%) and half-ICSI (60.7%) cycles were significantly (P < 0.01) higher than conventional IVF (42.6%) cycles. In the male immunological infertility group, fertilization rate was significantly (P < 0.01) higher in ICSI (60.7%) and half-ICSI (66.7%) cycles than in conventional IVF (27.4%) cycles and clinical pregnancy rate was higher in ICSI (54.5%) and half ICSI (33.3%) than in conventional IVF (25.0%) cycles.


CONCLUSIONS
We suggest that ICSI treatment is highly effective method to improve fertilization and pregnancy rate in IVF-ET program of male immunological infertility.
Jun
J H
JH
Infertility Research Laboratory, Samsung Cheil Hospital, Seoul, Korea.
Lim
C K
CK
Park
Y S
YS
Lee
Y S
YS
Seo
J T
JT
Son
I P
IP
Lee
H J
HJ
Kang
I S
IS
D003593:Cytoplasm / Q000276:immunology*; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D007246:Infertility / Q000276:immunology* / Q000628:therapy*; D007247:Infertility, Female / Q000276:immunology / Q000628:therapy; D007248:Infertility, Male / Q000276:immunology / Q000628:therapy; D008297:Male; D008845:Microinjections / Q000379:methods*; D009865:Oocytes / Q000276:immunology; D012189:Retrospective Studies; D013094:Spermatozoa / Q000637:transplantation*