title: [Predetermined epilations on the fixed areas of the face and forehead in a Tfm strain of mouse].
abstract: Many males and females with the bare skin area on their face were frequently observed in the Tfm strain of mouse representing testicular feminization. The predetermined epilation of oral and neighbouring hairs began at about ten months after birth and the subsequent bare skin area persisted for about 1 year to their death, but in some cases became expanded over the forehead. These facts indicate that this strain will be useful as a test animal for the detection if the effects of cosmetics and toiletry goods, medical drugs and so on. Microscopic examination of the epilation process revealed several morphological changes analogous to those in human male pattern baldness. However, in our case, several facts indicating that the androgens may stabilize hair growth, were discussed.
authors.affiliation: Institute of Functional Anatomy, Yamano College of Aesthetics, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Yamamoto
mesh_terms: D013734:Androgen-Insensitivity Syndrome / Q000235:genetics*; D000818:Animals; D005145:Face; D005260:Female; D005546:Forehead; D006197:Hair; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains