[An effect of chromatographic fraction ultrafiltrate of plasma on aggregation of blood platelets in patients with chronic uremia].
Chromatographic separation of ultrafiltrates from uremic patients on Sephadex A25 has showed that medium molecular weight substances were prior to the dialysis contained in 2 peaks in 6 patients, and in a single peak in 14 patients. The same substances were contained only in one peak after dialysis. Substances contained in the first peak inhibited blood platelets aggregation produced by ADP. Dialysis decreased this inhibitory effect.
Popławski
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Kliniki Nefrologii AM w Białymstoku.
Myśliwiec
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D000293:Adolescent; D000328:Adult; D002845:Chromatography; D005260:Female; D006440:Hemofiltration; D006801:Humans; D008297:Male; D008875:Middle Aged; D008970:Molecular Weight; D010974:Platelet Aggregation / Q000502:physiology*; D006435:Renal Dialysis; D014511:Uremia / Q000097:blood* / Q000628:therapy
Wpływ frakcji chromatograficznych ultrafiltratów osocza na agregacje krwinek płytkowych chorych na przewlekła mocznice.