title: CT in simple partial seizures in children: a clinical and computed tomography study.
abstract: BACKGROUND
  Therapeutic relevance of computed tomography (CT) in children with simple partial seizures (SPS) is reported to be remarkably low (1-2%). There are not studies, however, from the developing countries where neuroinfections are among important causes of seizures. The present study from India is aimed at evaluating the significance of CT in the management of SPS in children and to determine the difference in clinical features of children with and without focal brain lesions in CT.
  
  
  METHODS
  CT scans of all patients aged 15 years of younger with SPS, seen over a period of 15 months, were reviewed. The clinical features of the patients with focal lesions in the CT were compared with those of children without focal abnormalities.
  
  
  RESULTS
  Focal structural lesions were present in 117 (59.09%) of 198 children. These included: solitary contrast enhancing CT lesion-16.16%, focal calcification-12.12%, cysticerosis-10.10%, focal atrophy-9.59%, tuberculoma-6.56% and infarction-6.06%. Neuroinfections or their sequelae were responsible for seizures in 89 children (44.94%). There were no statistically significant differences in clinical features of patients with and without focal lesions in CT.
  
  
  CONCLUSIONS
  CT study in children with SPS in developing countries has significant therapeutic relevance. It is not possible to clinically differentiate children with focal lesions from those without focal lesions in CT.
authors.affiliation: Department of Neurology, National Institute of Mental Health and Neuro Sciences (NIMHANS), Bangalore, India.
authors.forename: K P
authors.initials: KP
authors.lastname: Nair
authors.forename: P N
authors.initials: PN
authors.lastname: Jayakumar
authors.forename: A B
authors.initials: AB
authors.lastname: Taly
authors.forename: G R
authors.initials: GR
authors.lastname: Arunodya
authors.forename: H S
authors.initials: HS
authors.lastname: Swamy
authors.forename: V
authors.initials: V
authors.lastname: Shanmugam
mesh_terms: D000293:Adolescent; D001284:Atrophy; D001921:Brain / Q000000981:diagnostic imaging* / Q000473:pathology; D002114:Calcinosis / Q000000981:diagnostic imaging; D002544:Cerebral Infarction / Q000000981:diagnostic imaging; D002648:Child; D002675:Child, Preschool; D003551:Cysticercosis / Q000000981:diagnostic imaging; D004828:Epilepsies, Partial / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006801:Humans; D007223:Infant; D011336:Probability; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014375:Tuberculoma / Q000000981:diagnostic imaging