[Cyclic oligonucleotides. II. Regularities in the formation of polycyclic structures].
Cyclization of a 38-mer oligodeoxyribonucleotide on a cyclic template was studied by the chemical and enzymic ligation methods. Both structures and yields of the reaction products depended on the ligation method and the nucleotide and template sequences. The chemical ligations resulted in the formation of catenanes, whose structures were confirmed by hydrolysis with the MvaI restriction endonuclease. Presence of G/C-rich clusters near the formed internucleotide bond favored the catenane formation.
Maksimenko
A V
AV
Fedorova
O A
OA
Gottikh
M B
MB
Kubareva
E A
EA
Shabarova
Z A
ZA
D009712:Nucleotides, Cyclic / Q000138:chemical synthesis*; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis*; D013698:Templates, Genetic
D009712:Nucleotides, Cyclic; D009838:Oligodeoxyribonucleotides
Tsiklicheskie oligonukleotidy. II. Izuchenie zakonomernosteĭ obrazovaniia politsiklicheskikh soedineniĭ.