A nosocomial outbreak due to Enterobacter cloacae strains with the E. hormaechei genotype in patients treated with fluoroquinolones.
During a 7-month period, we isolated 21 highly fluoroquinolone-resistant Enterobacter cloaecae strains in units from two hospitals in Marseille, France. Random amplification of polymorphic DNA showed clonal identity between isolates which, furthermore, presented the Enterobacter hormaechei genotype on DNA-DNA hybridization. The emergence of this clone was observed only in patients treated with fluoroquinolones.
Davin-Regli
A
A
AFCOPAT, Faculté de Pharmacie, Marseille, France.
Bosi
C
C
Charrel
R
R
Ageron
E
E
Papazian
L
L
Grimont
P A
PA
Cremieux
A
A
Bollet
C
C
D003428:Cross Infection; D004196:Disease Outbreaks; D004352:Drug Resistance, Microbial; D016972:Enterobacter cloacae / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections / Q000453:epidemiology / Q000382:microbiology*; D005602:France; D006801:Humans; D015363:Quinolones / Q000494:pharmacology*
D015363:Quinolones