Long-term treatment of elderly individuals with emotional disturbances: an open study with citalopram.
In the present open study, the long-term safety, tolerability, and efficacy of citalopram in the treatment of elderly people with emotional disturbances were studied. One hundred twenty-three elderly patients with symptoms of depression-anxiety were included. Most of the patients (76%) were demented. Fifty-two patients completed a 12-month treatment. Irritability, depressed mood, anxiety, restlessness, and fear-panic were significantly reduced. The severity of illness from baseline to Month 9 was rated as significantly improved. The side effects were infrequent and mostly mild.
Ragneskog
H
H
Department of Clinical Neuroscience, Göteborg University, Mölndal, Sweden.
Eriksson
S
S
Karlsson
I
I
Gottfries
C G
CG
D000342:Affective Symptoms / Q000188:drug therapy* / Q000523:psychology; D000368:Aged; D000544:Alzheimer Disease / Q000188:drug therapy* / Q000523:psychology; D000928:Antidepressive Agents / Q000008:administration & dosage* / Q000009:adverse effects; D001008:Anxiety Disorders / Q000188:drug therapy / Q000523:psychology; D015283:Citalopram / Q000008:administration & dosage* / Q000009:adverse effects; D015897:Comorbidity; D003704:Dementia / Q000188:drug therapy* / Q000523:psychology; D003866:Depressive Disorder / Q000188:drug therapy / Q000523:psychology; D005260:Female; D006801:Humans; D008134:Long-Term Care; D008297:Male; D013548:Sweden; D016896:Treatment Outcome
D000928:Antidepressive Agents; D015283:Citalopram