Eradication of communicative disorders: preventive medicine in the 21st century.
Profound changes in our society occurring over the past few decades have resulted in a major shift in societal emphasis from labor to communication. The widespread use of personal computers has enhanced the importance of information-communication in daily life. People with communication disorders are at substantial risk of underemployment and lowered quality of life. Advances in medical science and hearing health care have placed us on the thresholds of being able to correct, rather than remediate, certain types of hearing loss. The finding that auditory hair cells of submammalian species regenerate has stimulated greatly the field of auditory research. A new lexicon is required to describe this emerging field. Methods exist to protect against hearing loss, repair affected structures prior to their degeneration, promote dedifferentiation-redifferentiation of undamaged structures into sensory cells, and, finally, promote regeneration of new sensory cells from precursor cells. Each of these processes has unique requirements, and all may be required to promote the restoration of hearing following damage or disease.
Ruben
R J
RJ
Department of Otolaryngology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, New York 10467, USA.
D003051:Cochlea / Q000503:physiopathology; D003147:Communication Disorders / Q000517:prevention & control*; D003638:Deafness / Q000503:physiopathology / Q000517:prevention & control*; D004777:Environment; D005544:Forecasting; D006801:Humans; D007802:Language; D009925:Organ of Corti / Q000503:physiopathology; D011315:Preventive Medicine / Q000639:trends*