Kikuchi disease (histiocytic necrotizing lymphadenitis) in association with HTLV1.
We report a 25-year-old male with fever, generalized lymphadenopathy and an erythematosus maculo-papular eruption affecting face and upper body. A diagnosis of Kikuchi disease (necrotizing histiocytic lymphadenitis) was made on lymph node histology. The patient was found to be positive for the human T-cell leukaemia lymphoma virus (HTLV1). Kikuchi disease has been reported in association with infections such as Epstein-Barr virus (EBV), herpes (HHV6) and toxoplasmosis, but to our knowledge this is the first case of Kikuchi disease associated with HTLV1.
Bataille
V
V
Dermatology Department, St. Helier Hospital, Carshalton, Surrey, U.K.
Harland
C C
CC
Behrens
J
J
Cook
M G
MG
Holden
C A
CA
D000328:Adult; D015490:HTLV-I Infections / Q000150:complications* / Q000473:pathology; D015614:Histiocytosis / Q000473:pathology / Q000821:virology*; D006801:Humans; D008199:Lymphadenitis / Q000473:pathology / Q000821:virology*; D008297:Male