title: Generalized eigensystem techniques for the inverse problem of electrocardiography applied to a realistic heart-torso geometry.
abstract: We have previously proposed two novel solutions to the inverse problem of electrocardiography, the generalized eigensystem technique (GES) and the modified generalized eigensystem technique (tGES), and have compared these techniques with other numerical techniques using both homogeneous and inhomogeneous eccentric spheres model problems. In those studies we found our generalized eigensystem approaches generally gave superior performance over both truncated singular value decomposition (SVD) and zero-order Tikhonov regularization (TIK). In this paper we extend the comparison to the case of a realistic heart-torso geometry. With this model, the GES and tGES approaches again provide smaller relative errors between the true potentials and the numerically derived potentials than the other methods studied. In addition, the isopotential maps recovered using GES and tGES appear to be more accurate than the maps recovered using either SVD and TIK.
authors.affiliation: Department of Electrical Engineering, University of Nebraska, Lincoln 68588, USA. rthrone@unlinfo.unl.edu
authors.forename: R D
authors.initials: RD
authors.lastname: Throne
authors.forename: L G
authors.initials: LG
authors.lastname: Olson
authors.forename: T J
authors.initials: TJ
authors.lastname: Hrabik
authors.forename: J R
authors.initials: JR
authors.lastname: Windle
mesh_terms: D000818:Animals; D018780:Body Surface Potential Mapping; D006801:Humans; D008955:Models, Cardiovascular