[Extramedullary plasmacytoma with multiple metastasis following a maxillary plasmacytoma].
A 67-year old man noticed swelling of left maxillary in October 1992. Surgical biopsy of the left maxillary tumor revealed the plasmacytoma at the department of oral surgery. The Tumor disappeared after radiation therapy. He was admitted with dizziness and tarry stool in June 1994. We found left cervical and abdominal paraaortic lymph node swellings by the computer tomography. He died inspite of chemotherapy in December. Autopsy showed that plasma cells diffusely and nodularly invased in all alimentary tract with multiple ulcerations. Invasion was also observed in the liver, lungs, thyroid, heart, kidneys, and adrenals. The plasma cells in the liver showed IgG kappa type by tissue immunostain. Diffuse invasion of extramedullary plasmacytoma is very rare in alimentary tract and many other organs. This case may be value to delineate the nature of this disease.
Koike
M
M
Department of Hematology, Showa University School of Medicine.
Ishiyama
T
T
Hamano
Y
Y
Matuda
I
I
Hisatake
J
J
Hino
K
K
Tomoyasu
S
S
Tsuruoka
N
N
Iwase
M
M
Takimoto
M
M
Kushima
T
T
Oota
S
S
D000368:Aged; D005770:Gastrointestinal Neoplasms / Q000556:secondary; D006338:Heart Neoplasms / Q000556:secondary; D006801:Humans; D007680:Kidney Neoplasms / Q000556:secondary; D008113:Liver Neoplasms / Q000556:secondary; D008175:Lung Neoplasms / Q000556:secondary; D008297:Male; D008441:Maxillary Neoplasms / Q000473:pathology*; D010954:Plasmacytoma / Q000473:pathology* / Q000556:secondary*; D013964:Thyroid Neoplasms / Q000556:secondary