title: Penicillin resistance and autolysis in enterococci.
abstract: Comparison of several cell wall-related properties of the ATCC 9790 strain and the R40 strain, a penicillin-resistant, PBP5 overproducing strain, and Rev14, a penicillin-hypersensitive, PBP5-deficient strain, is consistent with a role of the genetic element, psr, in the global regulation of lysozyme sensitivity, autolytic capacity, and wall-rhamnose-containing polysaccharide content. These parameters appear to be independently regulated by a system that involves psr in a currently unknown manner.
authors.affiliation: Department of Microbiology and Immunology, Temple University, School of Medicine, Philadelphia, Pennsylvania 19140, USA.
authors.forename: L
authors.initials: L
authors.lastname: Daneo-Moore
authors.forename: O
authors.initials: O
authors.lastname: Massidda
authors.forename: R
authors.initials: R
authors.lastname: Kariyama
authors.forename: G D
authors.initials: GD
authors.lastname: Shockman
mesh_terms: D001329:Autolysis; D001426:Bacterial Proteins; D002352:Carrier Proteins / Q000378:metabolism; D002473:Cell Wall / Q000737:chemistry / Q000201:enzymology; D016983:Enterococcus / Q000187:drug effects* / Q000235:genetics / Q000502:physiology; D006602:Hexosyltransferases; D007527:Isoenzymes / Q000378:metabolism; D009113:Muramidase / Q000378:metabolism / Q000494:pharmacology; D002267:Muramoylpentapeptide Carboxypeptidase / Q000378:metabolism; D010403:Penicillin Resistance / Q000235:genetics; D046915:Penicillin-Binding Proteins; D010406:Penicillins / Q000378:metabolism; D010458:Peptidyl Transferases; D011523:Protoplasts / Q000187:drug effects / Q000201:enzymology
chemical_list: D001426:Bacterial Proteins; D002352:Carrier Proteins; D007527:Isoenzymes; D046915:Penicillin-Binding Proteins; D010406:Penicillins; D010458:Peptidyl Transferases; D006602:Hexosyltransferases; D009113:Muramidase; D002267:Muramoylpentapeptide Carboxypeptidase