[The influence of corticoids, in Chronic Chagas disease, administered in virtue of associated disorders].
Patients with chronic Chagas' disease and simultaneous medical problems treated with corticosteroid were studied in order to evaluate steroid influence on chronic Trypanosoma cruzi infection. Parasitological assessment, radiological and electrocardiographic studies as well as non specific tests were performed in patients and in a control group that included chronic infected patients not treated with steroid. Xenodiagnosis showed a clear increase in T. cruzi parasitemia, related to the corticosteroid dosage, without clinical manifestations during the study follow-up period.
Rassi
A
A
Departamento de Clínica Médica da Faculdade de Medicina da Universidade Federal de Goiás, Goiânia, Brasil.
Amato Neto
V
V
de Siqueira
A F
AF
Doles
J
J
Leite
M S
MS
Silva
O Q
OQ
Cardoso
V M
VM
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D000818:Animals; D014355:Chagas Disease / Q000150:complications / Q000469:parasitology; D002908:Chronic Disease; D005260:Female; D006321:Heart / Q000187:drug effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D051379:Mice; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D014349:Trypanosoma cruzi / Q000187:drug effects / Q000302:isolation & purification
D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents; D011241:Prednisone
Influência de corticóide, na doença de Chagas crônica, administrado em virtude de afecções associdas.