title: Red palm oil as a source of beta-carotene for combating vitamin A deficiency.
abstract: Twenty four school children of 7-9 years of age were divided into two groups of six boys and six girls each. One group was given a daily supplement of 'Suji halwa', a sweet snack made with semolina and red palm oil, supplying 2400 mu g of beta-carotene and the second group was the control group which was given 600 mu g of oral vitamin A palmitate, for 60 days. Vitamin A status before and after supplementation was assessed by the Modified Relative Dose Response Assay (MRDR). Results indicated that serum vitamin A levels increased from the basal level of 0.86 +/- 0.13 mu m mol/l to 1.891 +/- 0.23 mu mol/l in the Red Palmoil (RPO) group and from 0.74 +/- 0.09 to 1.94 +/- 0.21 mu mol/l in the control vitamin A group. Dehydroretinol/Retinol (DR/R) ratio decreased from 0.073 +/- 0.025 to 0.023 +/- 0.004 in the RPO group and from 0.090 +/- 0.023 to 0.023 +/- 0.004 in the vitamin A group, indicating liver saturation with vitamin A after feeding RPO snacks, comparable to synthetic vitamin A. This study indicates that RPO is an efficient source of beta-carotene which is found to be bioavailable in all the subjects tested, hence it can be used for supplementary feeding programmes to combat vitamin A deficiency in target population.
authors.affiliation: Post Graduate and Research Centre, A.P. Agricultural University, Rajendranagar, Hyderabad, India.
authors.forename: R
authors.initials: R
authors.lastname: Manorama
authors.forename: G N
authors.initials: GN
authors.lastname: Brahmam
authors.forename: C
authors.initials: C
authors.lastname: Rukmini
mesh_terms: D002648:Child; D004305:Dose-Response Relationship, Drug; D005260:Female; D005527:Food, Fortified; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D000073878:Palm Oil; D010938:Plant Oils / Q000737:chemistry* / Q000627:therapeutic use*; D012709:Serum Albumin / Q000032:analysis; D013997:Time Factors; D014801:Vitamin A / Q000097:blood; D014802:Vitamin A Deficiency / Q000097:blood / Q000178:diet therapy* / Q000453:epidemiology; D019207:beta Carotene / Q000032:analysis*
chemical_list: D010938:Plant Oils; D012709:Serum Albumin; D019207:beta Carotene; D014801:Vitamin A; D000073878:Palm Oil