HIV vaccines: problems and prospects.
Several lines of evidence now argue strongly that a successful HIV vaccine does not need to block infection completely. It has to mimic what already occurs in a minority of unvaccinated individuals--namely, rapid clearance of infection or reduction of viral load to a level that does not produce symptoms or permit transmission to others. The various vaccine candidates are reviewed.
Johnston
M I
MI
International AIDS Vaccine Initiative, Washington, DC, USA.
D016915:AIDS Vaccines / Q000276:immunology; D000818:Animals; D015195:Drug Design; D015497:HIV-1 / Q000145:classification / Q000235:genetics / Q000276:immunology*; D006801:Humans; D015302:Simian Immunodeficiency Virus / Q000276:immunology
D016915:AIDS Vaccines