[Antioxidants in the treatment of cholelithiasis patients].
Results of examination and treatment of 157 patients with cholelithiasis against the background of a liver pathology were summed up. The antioxidant system in such patients was studied. The degree of a decrease of catalase activity in the liver and blood serum as well as the ascorbic acid content were found to depend on the liver state of patients with cholelithiasis. Greatest changes were found in patients with cirrhosis of the liver and chronic active hepatitis. The method of complex treatment of cholelithiasis patients with non-enzymatic antioxidants alpha-tocopherol and ascorbic acid is proposed. Activity of organ specific liver enzymes urokaninase and histidase was used for the estimation of treatment efficiency. Complex administration of ascorbic acid and alpha-tocopherol was shown to improve the liver function in patients operated upon for cholelithiasis.
Vagner
E A
EA
Khlebnikov
V V
VV
Terekhina
N A
NA
Palatova
L F
LF
D000975:Antioxidants / Q000627:therapeutic use*; D001205:Ascorbic Acid / Q000032:analysis; D001646:Bile / Q000737:chemistry / Q000201:enzymology; D001706:Biopsy; D002374:Catalase / Q000032:analysis; D002769:Cholelithiasis / Q000378:metabolism / Q000628:therapy*; D003131:Combined Modality Therapy; D006521:Hepatitis, Chronic / Q000378:metabolism / Q000628:therapy; D006638:Histidine Ammonia-Lyase / Q000032:analysis; D006801:Humans; D008099:Liver / Q000737:chemistry / Q000201:enzymology / Q000473:pathology; D008103:Liver Cirrhosis / Q000378:metabolism / Q000628:therapy; D014559:Urocanate Hydratase / Q000032:analysis
D000975:Antioxidants; D002374:Catalase; D014559:Urocanate Hydratase; D006638:Histidine Ammonia-Lyase; D001205:Ascorbic Acid
Antioksidanty v lechenii bol'nykh kholelitiazom.