title: [Effect of glucose-insulin infusion on thallium-201 chloride tumor imaging].
abstract: Thallium-201 chloride (201Tl) kinetics, may be affected by serum insulin levels like potassium kinetics. The purpose of the present study was to use glucose and insulin to improve 201Tl accumulation in the tumor. The results showed that the tumor-to-normal tissue ratio after simultaneous injection of 201Tl, glucose and insulin was significantly higher than that after the injection of only 201Tl, and that a ring appearance seemed to occur after glucose and insulin injection. This preliminary study suggests that 201Tl accumulation in the tumor is enhanced by glucose and insulin administration.
authors.affiliation: Department of Radiology, Kagawa Medical University.
authors.forename: Y
authors.initials: Y
authors.lastname: Nishiyama
authors.forename: K
authors.initials: K
authors.lastname: Fukunaga
authors.forename: Y
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: K
authors.initials: K
authors.lastname: Satoh
authors.forename: H
authors.initials: H
authors.lastname: Takashima
authors.forename: M
authors.initials: M
authors.lastname: Ohkawa
authors.forename: M
authors.initials: M
authors.lastname: Tanabe
mesh_terms: D000818:Animals; D002279:Carcinoma 256, Walker / Q000000981:diagnostic imaging* / Q000378:metabolism; D005947:Glucose / Q000008:administration & dosage / Q000494:pharmacology*; D007328:Insulin / Q000008:administration & dosage / Q000494:pharmacology*; D011877:Radionuclide Imaging; D051381:Rats; D017208:Rats, Wistar; D013794:Thallium Radioisotopes / Q000493:pharmacokinetics
chemical_list: D007328:Insulin; D013794:Thallium Radioisotopes; D005947:Glucose