Skeletal muscle atrophy and peak oxygen consumption in heart failure.
We measured skeletal muscle mass and peak oxygen consumption (VO2) in 13 cachectic heart failure patients, 14 noncachectic patients, and in 52 healthy controls to examine skeletal muscle atrophy and its relation to low peak VO2 in heart failure patients. Our results show that skeletal muscle atrophy is associated with prior weight loss and is related to low peak VO2 in heart failure patients.
Toth
M J
MJ
Department of Medicine, University of Maryland, Baltimore VA Medical Center, USA.
Gottlieb
S S
SS
Fisher
M L
ML
Poehlman
E T
ET
D000368:Aged; D000704:Analysis of Variance; D001284:Atrophy; D005260:Female; D006333:Heart Failure / Q000473:pathology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000098:blood supply / Q000473:pathology*; D010101:Oxygen Consumption / Q000502:physiology*