title: Pleomorphic medium-sized T-cell lymphoma following Hodgkin's disease (nodular sclerosis type).
abstract: We describe a 32-year-old woman who presented with Hodgkin's disease, nodular sclerosis type II, subtype I, which necessitated several treatments over 11 years. The patient then developed pleomorphic, medium-sized T-cell lymphoma, which had a fatal outcome within 13 months. The role of radiotherapy, splenectomy, and chemotherapy in second tumor induction is compared with other sequential T-cell lymphomas. The significance of rare Epstein-Barr virus-infected cells during the T-cell lymphoma extension is discussed.
authors.affiliation: Service d'Anatomie Pathologique, Hôpital V. Dupouy, Argenteuil, France.
authors.forename: A
authors.initials: A
authors.lastname: Gaulier
authors.forename: F
authors.initials: F
authors.lastname: Teillet
authors.forename: F
authors.initials: F
authors.lastname: Davi
authors.forename: J
authors.initials: J
authors.lastname: Couturier
authors.forename: S
authors.initials: S
authors.lastname: Laye
authors.forename: M
authors.initials: M
authors.lastname: Raphael
mesh_terms: D000328:Adult; D005260:Female; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology*; D016399:Lymphoma, T-Cell / Q000473:pathology*; D016609:Neoplasms, Second Primary / Q000473:pathology*; D012598:Sclerosis