[The effect of plaferon on cerebral circulatory hypoxia in rabbits].
Local cerebral blood flow (LCBF) was reduced following plaferon administration in rabbits due to impairment of the vasodilator responses of cerebral vessels or their transformation into vasoconstrictor responses, the effect being added to that of vasoconstrictor responses to vasoactive neuropeptides contained in plaferon.
Kvrivishvili
G I
GI
Mitagvariia
N P
NP
D000818:Animals; D002545:Brain Ischemia / Q000188:drug therapy / Q000503:physiopathology; D002560:Cerebrovascular Circulation / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D002534:Hypoxia, Brain / Q000188:drug therapy* / Q000503:physiopathology; D009479:Neuropeptides / Q000494:pharmacology / Q000627:therapeutic use*; D011817:Rabbits; D013997:Time Factors; D014665:Vasodilator Agents / Q000494:pharmacology / Q000627:therapeutic use*
D009479:Neuropeptides; D014665:Vasodilator Agents; C091912:plaferon
Vliianie plaferona na tsirkuliatornuiu gipoksiiu golovnogo mozga krolikov.