[Storage of cadaver kidney by trans-organ oxygen insufflation].
Transorganic oxygen preservation was used in storage of 87 cadaver kidneys. The kidneys were stored for 14 to 56 h (34 +/- 1.95 on the average). After storage, all organs were transplanted to 87 patients with chronic renal insufficiency in the terminal stage. The patients age ranged from 18 to 55 years. All recipients were divided into 3 groups according to the results of the operation. Group 1 (55 patients)-the function of the organ was restored immediately, blood creatinine normalized on the 5th-10th postoperative day; subsidiary hemodialysis was not needed. Group 2 (22 patients)-the function of the transplant was restored 14-21 days after the operation; 2 to 8 sessions of hemodialysis had to be conducted. Group 3 (10 patients)-the transplant did not function due to acute irreversible canalicular necrosis or irreversible rejection. No correlative dependence between restoration of the transplant function and the duration of storage was noted (r = 0.15). Our experience allows us to assert that transorganic oxygen perfusion can ensure long-term safe storage of cadaver kidneys.
Belorusov
O S
OS
Scientific Center of Surgery, Moscow.
Asoian
G A
GA
Martyniuk
A P
AP
D000293:Adolescent; D000328:Adult; D002102:Cadaver; D005500:Follow-Up Studies; D006801:Humans; D007327:Insufflation / Q000379:methods*; D007668:Kidney / Q000502:physiology*; D016030:Kidney Transplantation / Q000502:physiology; D008875:Middle Aged; D009926:Organ Preservation / Q000379:methods*; D010100:Oxygen / Q000008:administration & dosage*
D010100:Oxygen
Konservirovanie trupnoi pochki transorgannoi kislorodnoi insuffliatsiei.