title: The natural history of the multicystic dysplastic kidney in children.
abstract: The objective of this study was to examine the natural history of the multicystic dysplastic kidney and the use of sonography for follow-up studies. A retrospective study was performed on 66 children with a radiological diagnosis of multicystic kidney. The change in size demonstrated on sonograms was examined. Adequate follow-up was available on 55 children over a period of 32 months (range 2-69 months). 40/55 of the kidneys underwent a reduction in size, including 22 which were no longer detectable by ultrasound. 10/55 kidneys showed an increase in size and 5/55 showed no change. Reduction in size occurred at a mean age of 84 weeks (range 20-120 weeks). In conclusion, most multicystic kidneys undergo partial or complete involution over the first 2 years of life. The mean size of the multicystic kidney at diagnosis is a poor predictor of eventual outcome.
authors.affiliation: Department of Radiology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: G T
authors.initials: GT
authors.lastname: Rottenberg
authors.forename: I
authors.initials: I
authors.lastname: Gordon
authors.forename: R
authors.initials: R
authors.lastname: De Bruyn
mesh_terms: D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007690:Polycystic Kidney Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D011379:Prognosis; D012075:Remission, Spontaneous; D012189:Retrospective Studies; D014463:Ultrasonography