title: Interdependence between Zn and Cu serum concentrations and serum immunoglobulins (IgA, IgM, IgG) in liver diseases.
abstract: The object of this study was to find out, by means of statistical-mathematical methods, whether the serum concentrations of Zn and Cu had a role in the interrelation among immunoglobulins IgA, IgM, IgG in four groups of subjects with various forms of liver diseases. It was found that the correlation structure between IgA, IgM, IgG and the serum concentration of Zn or Cu were different in the four types of diseases studied, and also that of these two metal ions, Zn was the most important, influencing the interdependence between the immunoglobulins in the active forms of disease.
authors.affiliation: N. Gh. Lupu Institute of Internal Medicine, Bucharest, Romania.
authors.forename: C
authors.initials: C
authors.lastname: Tănăsescu
authors.forename: R
authors.initials: R
authors.lastname: Băldescu
authors.forename: Z
authors.initials: Z
authors.lastname: Chirulescu
mesh_terms: D000208:Acute Disease; D000704:Analysis of Variance; D003300:Copper / Q000097:blood*; D006506:Hepatitis A / Q000097:blood*; D006509:Hepatitis B / Q000097:blood*; D006526:Hepatitis C / Q000097:blood*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D007074:Immunoglobulin G / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood*; D008103:Liver Cirrhosis / Q000097:blood*; D012044:Regression Analysis; D015032:Zinc / Q000097:blood*
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D003300:Copper; D015032:Zinc