title: [An update on parathyroid surgery].
abstract: The operative management of patients with hyperparathyroidism is controversial. High rates of persistent hypercalcemia and postoperative hypoparathyroidism are seen in multiple hyperplasia and bilateral neck exploration. Patients undergoing unilateral neck exploration with removal of a single parathyroid adenoma have a rapid clearance of PTH which declines within hours after surgery. There is a sensitive immunometric assay (IRMA) for the intact molecule which demonstrates a decline in 15 minutes during surgery. Intraoperative measurement of PTH may be complementary to surgical skill and histopathologic information and may modulate extension of neck exploration.
authors.affiliation: Dipartimento di Chirurgia ed Emergenze Chirurgiche, Università degli Studi di Perugia.
authors.forename: P
authors.initials: P
authors.lastname: Campi
authors.forename: R
authors.initials: R
authors.lastname: Cristofani
authors.forename: M F
authors.initials: MF
authors.lastname: Burattini
authors.forename: A
authors.initials: A
authors.lastname: Servoli
authors.forename: A
authors.initials: A
authors.lastname: Morabito
authors.forename: E
authors.initials: E
authors.lastname: Moriconi
authors.forename: V
authors.initials: V
authors.lastname: Scalercio
authors.forename: E
authors.initials: E
authors.lastname: Ricci
authors.forename: V
authors.initials: V
authors.lastname: Lauro
authors.forename: M
authors.initials: M
authors.lastname: Prestipino
authors.forename: C
authors.initials: C
authors.lastname: Bussotti
authors.forename: I
authors.initials: I
authors.lastname: Sabalich
authors.forename: A
authors.initials: A
authors.lastname: Bartoli
mesh_terms: D000236:Adenoma / Q000150:complications / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000368:Aged; D001707:Biopsy, Needle; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010280:Parathyroid Glands / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D010281:Parathyroid Hormone / Q000097:blood; D010282:Parathyroid Neoplasms / Q000150:complications / Q000601:surgery; D016105:Parathyroidectomy; D011877:Radionuclide Imaging; D014463:Ultrasonography
chemical_list: D010281:Parathyroid Hormone
vernacular_title: Attualità in tema di chirurgia delle paratiroidi.