[Coexistence of chronic lymphoid leukemia and Hodgkin's disease. Immunohistochemical study].
We report a new case of coincidence of chronic lymphocytic leukemia (CLL) and mixed cellularity Hodgkin's disease (HD) in the same lymph node. These findings were corroborated by immunohistochemical study showing Reed-Sternberg (RS) cells, with typical immunophenotype in an inflammatory background, closely related to a small neoplastic lymphoid cell population. This is an uncommon feature, and, to our knowledge, this is the first case published in the Spanish literature.
Pérez del Río
M J
MJ
Servicio de Anatomía Patológica, Hospital Ntra, Universidad de Oviedo.
Fresno
M F
MF
Ramírez
A
A
Veiga
M
M
González
M
M
Herrero
A
A
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002699:Chlorambucil / Q000008:administration & dosage; D006689:Hodgkin Disease / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D016130:Immunophenotyping; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy / Q000473:pathology*; D011241:Prednisone / Q000008:administration & dosage
D002699:Chlorambucil; D011241:Prednisone
Coincidencia de leucemia linfoide crónica y enfermedad de Hodgkin. Estudio inmunohistoquímico.