Beneficial effect of lovastatin on sphincter of Oddi dyskinesia in hypercholesterolemia and hypertriglyceridemia.
This report describes an impaired sphincter of Oddi relaxation function in relation to hypercholesterolemia and hypertriglyceridemia. As indicated by repetitive amyl nitrite-augmented quantitative hepatobiliary scintgraphy, normalization of serum lipids by means of diet and a 3-month treatment period with 20 mg of lovastatin per day resulted in an improvement of sphincter of Oddi relaxation.
Szilvássy
Z
Z
First Department of Medicine, Albert Szent-Gyorgyi Medical University Szeged, Hungary.
Nagy
I
I
Madácsy
L
L
Hajnal
F
F
Velösy
B
B
Takács
T
T
Lonovics
J
J
D000368:Aged; D000924:Anticholesteremic Agents / Q000627:therapeutic use*; D001649:Bile Duct Diseases / Q000188:drug therapy / Q000209:etiology; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications / Q000188:drug therapy*; D015228:Hypertriglyceridemia / Q000150:complications / Q000188:drug therapy*; D008148:Lovastatin / Q000627:therapeutic use*; D009069:Movement Disorders / Q000188:drug therapy / Q000209:etiology; D009803:Sphincter of Oddi / Q000187:drug effects*
D000924:Anticholesteremic Agents; D008148:Lovastatin