title: The levonorgestrel intrauterine system in the management of menorrhagia.
abstract: OBJECTIVE
  To assess the effect of a levonorgestrel releasing intrauterine system in the management of menorrhagia.
  
  
  METHODS
  A prospective study.
  
  
  METHODS
  A district general hospital in South Wales.
  
  
  METHODS
  Fifty women with a failed trial of medical therapy and awaiting hysterectomy or transcervical resection of the endometrium (TCRE) were treated with a levonorgestrel intrauterine system. The menstrual loss was estimated using a modified pictorial chart together with a full blood count and ferritin measurement preinsertion and at three and six to nine months postinsertion.
  
  
  RESULTS
  The menstrual loss was reduced to acceptable levels in 37 women at three months and a further four by six to nine months. In all, 41 patients were taken off the waiting list for surgery, four of whom became amenorrhoeic. There was no significant change in full blood count nor ferritin measurement despite unscheduled bleeding for six to eight weeks postinsertion. Fifty-six percent of patients noticed considerable improvement or cure of their premenstrual syndrome symptoms; 80% noted a reduction in dysmenorrhoea.
  
  
  CONCLUSIONS
  The levonorgestrel releasing intrauterine system is an effective nonsurgical treatment for the management of menorrhagia and dysmenorrhoea that has additional benefit as a contraceptive and in relieving premenstrual syndrome.
authors.affiliation: Department of Obstetrics and Gynaecology, Singleton Hospital, Swansea.
authors.forename: J W
authors.initials: JW
authors.lastname: Barrington
authors.forename: P
authors.initials: P
authors.lastname: Bowen-Simpkins
mesh_terms: D000328:Adult; D003271:Contraceptive Agents, Female / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007436:Intrauterine Devices, Medicated; D016912:Levonorgestrel / Q000008:administration & dosage*; D008595:Menorrhagia / Q000188:drug therapy*; D008598:Menstruation; D008875:Middle Aged; D010358:Patient Participation; D011446:Prospective Studies
chemical_list: D003271:Contraceptive Agents, Female; D016912:Levonorgestrel