Embolia cutis medicamentosa.
A 35-year-old man presented with a painful skin necrosis after a deep ventrogluteal injection of diclofenac and dexamethasone for treatment of severe back pain. Immediately after the injection, the patient felt a strong pain just above the injection site. In the following days a remarkable necrosis developed in the upper gluteal region. Topical therapy with antiseptics and a topical corticosteroid cream plus analgesia with tramadole revealed no improvement of the symptoms. We excised the necrotic area. Within 1 day, the patient was without pain.
Köhler
L D
LD
Department of Dermatology, Technical University of Munich, Germany.
Schwedler
S
S
Worret
W I
WI
D000328:Adult; D003907:Dexamethasone / Q000008:administration & dosage / Q000009:adverse effects; D004008:Diclofenac / Q000008:administration & dosage / Q000009:adverse effects; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D004617:Embolism / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007273:Injections, Intramuscular / Q000009:adverse effects*; D008297:Male; D009336:Necrosis; D012867:Skin / Q000098:blood supply / Q000473:pathology
D004008:Diclofenac; D003907:Dexamethasone