Cell migration: don't tread on me.
During directed cell migration, telling cells to avoid certain areas may be as important as attracting them to others. The recently identified wunen gene is involved in the repulsive guidance of migrating primordial germ cells in Drosophila.
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Developmental Genetics Program, Skirball Institute, NYU Medical Center, 540 First Avenue, New York, New York 10016, USA.
Lehmann
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D000818:Animals; D019070:Cell Lineage; D002465:Cell Movement / Q000502:physiology*; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000196:embryology / Q000235:genetics*; D004625:Embryo, Nonmammalian / Q000166:cytology; D018507:Gene Expression Regulation, Developmental; D005854:Germ Cells / Q000166:cytology*; D019476:Insect Proteins / Q000235:genetics / Q000502:physiology*; D008565:Membrane Proteins / Q000235:genetics / Q000502:physiology*; D010711:Phosphatidate Phosphatase
D029721:Drosophila Proteins; D019476:Insect Proteins; D008565:Membrane Proteins; D010711:Phosphatidate Phosphatase; C103065:wun protein, Drosophila