title: Coli surface antigens associated with enterotoxigenic Escherichia coli strains isolated from persons with traveler's diarrhea in Asia.
abstract: Enterotoxigenic Escherichia coli (ETEC) strains were isolated from travelers or military personnel who developed diarrhea after visiting Nepal or who were deployed to Thailand, Indonesia, or the Philippines. ETEC isolates were examined for colonization factor antigen (CFA). CFAs were identified on 59% (40 of 68) of the isolates examined. The lack of a detectable CFA on 41% (28 of 68) of the isolates is of concern for the development of an effective ETEC vaccine.
authors.affiliation: Department of Bacteriology, Immunology, and Molecular Genetics, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
authors.forename: O
authors.initials: O
authors.lastname: Serichantalergs
authors.forename: W
authors.initials: W
authors.lastname: Nirdnoy
authors.forename: A
authors.initials: A
authors.lastname: Cravioto
authors.forename: C
authors.initials: C
authors.lastname: LeBron
authors.forename: M
authors.initials: M
authors.lastname: Wolf
authors.forename: A M
authors.initials: AM
authors.lastname: Svennerholm
authors.forename: D
authors.initials: D
authors.lastname: Shlim
authors.forename: C W
authors.initials: CW
authors.lastname: Hoge
authors.forename: P
authors.initials: P
authors.lastname: Echeverria
mesh_terms: D000942:Antigens, Bacterial / Q000032:analysis*; D000954:Antigens, Surface / Q000032:analysis; D001208:Asia; D001426:Bacterial Proteins / Q000032:analysis*; D003967:Diarrhea / Q000382:microbiology*; D004768:Enterotoxins / Q000032:analysis; D004926:Escherichia coli / Q000737:chemistry* / Q000235:genetics / Q000276:immunology; D004927:Escherichia coli Infections / Q000382:microbiology*; D036781:Fimbriae Proteins; D005798:Genes, Bacterial; D006801:Humans; D008889:Military Personnel; D014195:Travel; D014481:United States
chemical_list: D000942:Antigens, Bacterial; D000954:Antigens, Surface; D001426:Bacterial Proteins; D004768:Enterotoxins; C022924:colonization factor antigens; D036781:Fimbriae Proteins