title: Improving the results of ganglion aspiration by the use of hyaluronidase.
abstract: We present the results of a prospective randomized trial comparing the treatment of ganglia by aspiration under local anaesthetic and either instillation of steroid alone or with the prior use of hyaluronidase. Thirty-five patients were treated in each group and followed up for 2 years. The cure rate with the combined use of hyaluronidase and methylprednisolone was 89%, compared to 57% when treated by aspiration and instillation of methylprednisolone alone.
authors.affiliation: Department of Orthopaedic Surgery, Manchester Royal Infirmary, UK.
authors.forename: A S
authors.initials: AS
authors.lastname: Paul
authors.forename: D H
authors.initials: DH
authors.lastname: Sochart
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000627:therapeutic use*; D007322:Instillation, Drug; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D011446:Prospective Studies; D013396:Suction; D013581:Synovial Cyst / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome; D014953:Wrist
chemical_list: D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D006821:Hyaluronoglucosaminidase; D008775:Methylprednisolone