Future clinical research with icodextrin-containing solutions.
Icodextrin-based solutions have been investigated for over ten years and are commercially available in some countries in Europe. Although many studies have been described using icodextrin, we believe that there are many interesting areas remaining for clinical research with icodextrin-based PD solutions. Included in these are the careful examination of the kinetics of icodextrin during the 14-16 hour daytime exchange in CCPD, new studies investigating fluid absorption during icodextrin exchanges, and finally, the potential use of icodextrin in an early start dialysis regime. We look forward to seeing the results from these very interesting studies.
Shockley
T R
TR
Renal Division-Scientific Affairs, Baxter Healthcare Corporation, McGaw Park, Illinois 60085, USA.
Wang
T
T
Lindholm
B
B
D000042:Absorption; D002986:Clinical Trials as Topic / Q000639:trends; D015314:Dialysis Solutions; D005936:Glucans; D005947:Glucose; D006801:Humans; D000077607:Icodextrin; D007676:Kidney Failure, Chronic / Q000628:therapy; D010530:Peritoneal Dialysis; D010531:Peritoneal Dialysis, Continuous Ambulatory; D014462:Ultrafiltration
D015314:Dialysis Solutions; D005936:Glucans; D000077607:Icodextrin; D005947:Glucose