title: [Iatrogenic collapse; can this be prevented?].
abstract: In four patients, two men aged 65 and 35 years, and two women aged 87 and 83 years, who presented with collapse, administration of Q-T time prolonging drugs (sotalol, erythromycin, disopyramide) appeared to be the cause. These patients had so-called 'concealed long Q-T syndrome'. The proarrhythmogenic properties of antiarrhythmic and other drugs and of several clinical conditions such as cardiac diseases should be kept in mind when treating patients with antiarrhythmic substances.
authors.affiliation: Diakonessenhuis, afd. Cardiologie, Utrecht.
authors.forename: N M
authors.initials: NM
authors.lastname: Panhuyzen-Goedkoop
authors.forename: H J
authors.initials: HJ
authors.lastname: Crijns
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D004206:Disopyramide / Q000009:adverse effects; D004917:Erythromycin / Q000009:adverse effects; D005260:Female; D006801:Humans; D008133:Long QT Syndrome / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged; D013015:Sotalol / Q000009:adverse effects; D013575:Syncope / Q000139:chemically induced*
chemical_list: D000889:Anti-Arrhythmia Agents; D000900:Anti-Bacterial Agents; D004917:Erythromycin; D013015:Sotalol; D004206:Disopyramide
vernacular_title: Iatrogene collaps; is die te voorkomen?