title: Recurrence of hydrosalpinges after transvaginal aspiration of tubal fluid in an IVF cycle with development of a serometra.
abstract: The presence of hydrosalpinges has been shown to be deleterious in infertility treatment. Pregnancy rates after in-vitro fertilization (IVF) with embryo transfer decline considerably. This study concerns a patient who developed bilateral hydrosalpinges during controlled ovarian stimulation in preparation for IVF treatment. Transvaginal aspiration of the tubal fluid was unsuccessful as the tubes refilled within 2 days. Additionally, on the day of embryo transfer a serometra developed which could not be seen on the day of oocyte retrieval. The uterine cavity was evacuated via an embryo transfer catheter and three embryos were transferred. The serometra reappeared 3 days after embryo transfer. A pregnancy could not be achieved. The accumulation of fluid in the uterine cavity during an IVF/embryo transfer cycle is a rare complication of hydrosalpinges. However, the retrograde flow of tubal fluid may disturb intrauterine embryo development. This study suggests that the aspiration of hydrosalpinges and intrauterine fluid accumulation during an IVF cycle is not beneficial, as the underlying pathology is not cured. Cancellation of the treatment cycle or cryopreservation of oocytes in the pronucleate stage and transfer of the cryopreserved oocytes after surgical correction of the tubes may be better options.
authors.affiliation: Department of Reproductive Medicine and Endocrinology, University Clinic of Obstetrics and Gynecology, Charité, Humboldt University, Berlin, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Bloechle
authors.forename: T
authors.initials: T
authors.lastname: Schreiner
authors.forename: K
authors.initials: K
authors.lastname: Lisse
mesh_terms: D005122:Exudates and Transudates; D005184:Fallopian Tube Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000209:etiology*; D011247:Pregnancy; D018873:Pregnancy Rate; D012008:Recurrence; D013396:Suction; D016896:Treatment Outcome; D014463:Ultrasonography; D014591:Uterine Diseases / Q000150:complications*; D014621:Vagina