title: Nonpenetrating, arcuate-legged clip reconstruction of the rat uterine horn.
abstract: A new method for reconstructing rat uterine horn was developed in which nonpenetrating, arcuate-legged clips are applied in interrupted fashion to everted seromuscular edges, forming an elastomeric flanged joint. This anastomosis has unusual physical and morphologic properties, with improved tissue healing and luminal restitution. Clipping is easier than suturing, and resulted in equivalent fertility rate (50-60%) and litter size. It also is associated with less granuloma formation and hystiocytic infiltration than suture. The new technique has the potential of endoscopic translation for human tubal reconstruction.
authors.affiliation: Loma Linda University Medical Center, Room 2539, 11234 Anderson Street, Loma Linda, CA 92350, USA.
authors.forename: Y H
authors.initials: YH
authors.lastname: Zhu
authors.forename: W M
authors.initials: WM
authors.lastname: Kirsch
authors.forename: D
authors.initials: D
authors.lastname: Tredway
authors.forename: K
authors.initials: K
authors.lastname: Weber
authors.forename: M
authors.initials: M
authors.lastname: Norburg
authors.forename: G W
authors.initials: GW
authors.lastname: Saukel
authors.forename: K C
authors.initials: KC
authors.lastname: Oberg
authors.forename: I
authors.initials: I
authors.lastname: Seraj
authors.forename: J
authors.initials: J
authors.lastname: Chrisler
mesh_terms: D000714:Anastomosis, Surgical / Q000295:instrumentation / Q000379:methods; D000818:Animals; D016009:Chi-Square Distribution; D004195:Disease Models, Animal; D005260:Female; D020706:Laparoscopes; D008866:Microsurgery / Q000295:instrumentation*; D011183:Postoperative Complications / Q000473:pathology; D011247:Pregnancy; D011256:Pregnancy Outcome; D051381:Rats; D017207:Rats, Sprague-Dawley; D012016:Reference Values; D018709:Statistics, Nonparametric; D013525:Surgical Instruments; D017792:Surgical Stapling / Q000295:instrumentation* / Q000379:methods; D014599:Uterus / Q000033:anatomy & histology / Q000601:surgery*; D014945:Wound Healing / Q000502:physiology