T-cell subsets: recruiting the right kind of help.
The qualitative features of immune responses are influenced by the polarization of helper T cells towards two distinct phenotypes, Th1 and Th2. Recent evidence suggests that these helper cell subsets may be differentially recruited to the sites of different types of inflammatory reaction.
Lichtman
A H
AH
Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, 221 Longwood Avenue, Boston, Massachusetts 02160, USA.
Abbas
A K
AK
D000818:Animals; D015815:Cell Adhesion Molecules / Q000502:physiology; D018925:Chemokines / Q000502:physiology; D006801:Humans; D007249:Inflammation / Q000276:immunology; D007962:Leukocytes / Q000502:physiology; D018448:Models, Immunological; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D018417:Th1 Cells / Q000276:immunology*; D018418:Th2 Cells / Q000276:immunology*
D015815:Cell Adhesion Molecules; D018925:Chemokines