title: [The intra-aortic antibacterial therapy of wounded patients with gunshot meningoencephalitis].
abstract: The original decision of permanent introduction of antibacterial means to tissues of brain at gunshot meningoencephalitis is offered. For antibacterial therapy the intra-aortal catheter with diameter of 2,5 mm (through a.femoralis) was introduced. After washing the catheter by solution of crystalloid with heparin the various combinations of preparations in 5% solution of glucose were introduced: cephalosporin--8 g/day; hentamicin and brumacilin--240 mg/day accordingly, amicacin--1500 mg/day. Speed of introduction--20-50 mg/h, total volume--500 ml. The catheter was in aorta not more than 10 days, maximum--14 days. A described technique was applied in Burdenko Main Military Clinical Hospital on 34 wounded in head. At computer tomography of brain of all wounded intracranially the splinters and bullets were revealed, clinically--meningoencephalitis. Foreign bodies have been extracted after cupping of clinical and laboratory signs of meningoencephalitis. The authors consider, that the technique is effective not only at wounds of brain, but also at suppurative meningoencephalitis of other etiology.
authors.forename: S V
authors.initials: SV
authors.lastname: Murashkin
authors.forename: S V
authors.initials: SV
authors.lastname: Efremenko
authors.forename: Iu V
authors.initials: IuV
authors.lastname: Luzganov
authors.forename: V A
authors.initials: VA
authors.lastname: Belov
mesh_terms: D000293:Adolescent; D000328:Adult; D000890:Anti-Infective Agents / Q000008:administration & dosage*; D001011:Aorta; D001930:Brain Injuries / Q000150:complications / Q000188:drug therapy*; D002406:Catheterization, Peripheral / Q000379:methods; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000379:methods; D008297:Male; D008590:Meningoencephalitis / Q000188:drug therapy* / Q000209:etiology; D008875:Middle Aged; D008889:Military Personnel; D012426:Russia; D014948:Wounds, Gunshot / Q000150:complications / Q000188:drug therapy*
chemical_list: D000890:Anti-Infective Agents
vernacular_title: Vnutriaortal'naia antibakterial'naia terapiia ranenykh s ognestrel'nym meningoéntsefalitom.