title: [Idiopathic CD4(+)-T-lymphocytopenia].
abstract: Three patients, two men aged 27 and 33 years and one woman aged 31 years, developed several opportunistic infections without presence of HIV infection. Patient A died after suffering Candida stomatitis, extrapulmonary Mycobacterium avium infection, cytomegalovirus infection and Aspergillus pneumonia; patient B recovered from a disseminated M. kansasii infection; patient C suffered from verrucae planae. These patients had CD4(+)-T lymphocytopenia, a shortage of helper T cells. Idiopathic CD4(+)-T lymphocytopenia is a heterogeneous pathological condition with normal serum immunoglobulin concentrations. Treatment consists of combating and preventing infections.
authors.affiliation: Academisch Ziekenhuis, afd. Inwendige Geneeskunde, Nijmegen.
authors.forename: M J
authors.initials: MJ
authors.lastname: van de Ven
authors.forename: J W
authors.initials: JW
authors.lastname: Lenders
authors.forename: A A
authors.initials: AA
authors.lastname: Baas
authors.forename: A C
authors.initials: AC
authors.lastname: Holdrinet
authors.forename: J W
authors.initials: JW
authors.lastname: van der Meer
mesh_terms: D000328:Adult; D015496:CD4-Positive T-Lymphocytes; D005260:Female; D006801:Humans; D008231:Lymphopenia / Q000150:complications* / Q000175:diagnosis; D008297:Male; D009894:Opportunistic Infections / Q000209:etiology* / Q000517:prevention & control
vernacular_title: Idiopathische CD4(+)-T-lymfocytopenie.