title: [Lumbar disk prolapse surgery with or without free fat transplantation. A prospective triple-blind randomized study].
abstract: The aim of this prospective triple-blind randomized study was to determine if a free fat transplant used in operation in lumbar disc herniation could reduce the degree of intraspinal scar tissue and to evaluate whether the scar tissue could lead to symptoms. Ninety-nine patients were subsequently examined after median 376 days. The clinical outcome was scored using the Low Back Pain Rating Scale. Enhanced CT-scanning was assessed regarding the degree of scar tissue and survival of the fat transplant. There was no difference in the clinical outcome between the two groups. Significantly fewer had dural scarring in the group who had a free fat transplantation, but there was no difference regarding the degree of radicular scarring. The transplant was shown on CT-scan at the follow-up examination in 66% of the patients who had a fat transplantation. Free fat transplantation can reduce the degree of dural scar tissue after operation for lumbal disc herniation, but does not result in a clinically better outcome.
authors.affiliation: Hillerød Sygehus, ortopaedkirurgisk afdeling, reumatologisk afdeling og billeddiagnostisk afdeling.
authors.forename: T T
authors.initials: TT
authors.lastname: Jensen
authors.forename: K H
authors.initials: KH
authors.lastname: Asmussen
authors.forename: E B
authors.initials: EB
authors.lastname: Rose-Hansen
authors.forename: B U
authors.initials: BU
authors.lastname: Lauritsen
authors.forename: C
authors.initials: C
authors.lastname: Manniche
authors.forename: H
authors.initials: H
authors.lastname: Vinterberg
authors.forename: L E
authors.initials: LE
authors.lastname: Jensen
authors.forename: J
authors.initials: J
authors.lastname: Kramhøft
mesh_terms: D000273:Adipose Tissue / Q000637:transplantation*; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000175:diagnosis / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D011446:Prospective Studies
vernacular_title: Lumbal diskusprolaps-operation med eller uden fri fedt-transplantation. Prospektivt tripelblindt randomiseret studie.