title: Frontal cortical atrophy and negative symptoms in patients with chronic alcohol dependence.
abstract: It has been suggested that frontal lobe pathology is associated with negative symptoms in patients with chronic alcoholism. In his exploratory study, the authors examined 19 chronic alcoholic inpatients on an alcohol treatment unit and found a significant relationship between severity of frontal atrophy (as measured by CT) and negative symptoms (as measured by the Scale for the Assessment of Negative Symptoms).
authors.affiliation: Psychiatry Service, Department of Veterans Affairs Medical Center, Washington, DC 20422, USA.
authors.forename: R B
authors.initials: RB
authors.lastname: Rosse
authors.forename: R L
authors.initials: RL
authors.lastname: Riggs
authors.forename: A M
authors.initials: AM
authors.lastname: Dietrich
authors.forename: B L
authors.initials: BL
authors.lastname: Schwartz
authors.forename: S I
authors.initials: SI
authors.lastname: Deutsch
mesh_terms: D000293:Adolescent; D000328:Adult; D000437:Alcoholism / Q000175:diagnosis*; D001284:Atrophy / Q000473:pathology*; D002908:Chronic Disease; D005625:Frontal Lobe / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010296:Parietal Lobe / Q000473:pathology*; D011569:Psychiatric Status Rating Scales; D012720:Severity of Illness Index