The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor.
Brown
M S
MS
Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas 75235, USA.
Goldstein
J L
JL
D000818:Animals; D022762:CCAAT-Enhancer-Binding Proteins; D002784:Cholesterol / Q000378:metabolism*; D004268:DNA-Binding Proteins / Q000378:metabolism*; D018257:Helix-Loop-Helix Motifs / Q000502:physiology; D006801:Humans; D016350:Leucine Zippers / Q000502:physiology; D008565:Membrane Proteins / Q000378:metabolism*; D009687:Nuclear Proteins / Q000378:metabolism*; D051780:Sterol Regulatory Element Binding Protein 1; D014157:Transcription Factors / Q000378:metabolism*
D022762:CCAAT-Enhancer-Binding Proteins; D004268:DNA-Binding Proteins; D008565:Membrane Proteins; D009687:Nuclear Proteins; C497387:SREBF1 protein, human; D051780:Sterol Regulatory Element Binding Protein 1; D014157:Transcription Factors; D002784:Cholesterol