title: Cardiopulmonary by-pass in a patient with acquired C1 inhibitor deficiency.
abstract: C1 inhibitor (C1-INH) regulates, complement, contact system, coagulation and fibrinolysis. Bleeding complications during cardiopulmonary bypass (CPB) have been described in a deficient patient. We report a 72 year old man affected with acquired C1-INH deficiency who successfully underwent CPB.
authors.affiliation: Institute of Internal Medicine, University of Milano, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Castelli
authors.forename: M
authors.initials: M
authors.lastname: Cicardi
authors.forename: M
authors.initials: M
authors.lastname: Gardinali
authors.forename: L C
authors.initials: LC
authors.lastname: Zingale
authors.forename: C
authors.initials: C
authors.lastname: Savi
authors.forename: M
authors.initials: M
authors.lastname: Munari
authors.forename: A
authors.initials: A
authors.lastname: Agostoni
mesh_terms: D000368:Aged; D045930:Anabolic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000799:Angioedema / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D000933:Antifibrinolytic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D007611:Aprotinin / Q000627:therapeutic use; D001327:Autoimmune Diseases / Q000097:blood / Q000150:complications* / Q000188:drug therapy; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000627:therapeutic use; D002315:Cardiopulmonary Bypass; D003167:Complement Activation; D003174:Complement C1 Inactivator Proteins / Q000172:deficiency*; D001026:Coronary Artery Bypass; D006490:Hemostatics / Q000627:therapeutic use; D006494:Heparin Antagonists / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007819:Laryngeal Edema / Q000150:complications / Q000188:drug therapy / Q000209:etiology; D008297:Male; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy / Q000601:surgery; D011183:Postoperative Complications / Q000517:prevention & control; D011479:Protamines / Q000008:administration & dosage / Q000627:therapeutic use; D012008:Recurrence; D013197:Stanozolol / Q000008:administration & dosage / Q000627:therapeutic use; D014148:Tranexamic Acid / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D045930:Anabolic Agents; D000933:Antifibrinolytic Agents; D002121:Calcium Channel Blockers; D003174:Complement C1 Inactivator Proteins; D006490:Hemostatics; D006494:Heparin Antagonists; D011479:Protamines; D013197:Stanozolol; D014148:Tranexamic Acid; D007611:Aprotinin