title: Incidence of wound infection in three different departments and the antibiotic sensitivity pattern of the isolates in a Saudi Arabian hospital.
abstract: The incidence of wound infection in three different departments: general surgery (GS), interdisciplinary intensive care (IIC) and pediatric intensive care (PIC) in King Khalid Hospital in Hail was studied during the hot months June-October. A total of 2,331 wounds were examined. One hundred and ninety-three of them were infected (8%). The overall monthly infection rates in these departments were significantly different. They were 18, 9 and 4% in the IIC, GS, and PIC respectively. The monthly infection rates varied, the highest rates occurred in July. Two hundred and eighty three strains were isolated from the infected wounds. Seventy ones were isolated during June, and 69, 60, 42 and 41 strains were isolated during July, October, August and September, respectively- Thirty five per cent of these strains were identified as Staphylococcus aureus, 31% as Escherichia coli, 25% as Pseudomonas aeruginosa, and 10% as Klebsiella. S. aureus was the predominant organism during July; while E. coli predominated during August and October. S. aureus and P. aeruginosa strains were isolated in equal numbers during June. The sensitivity of these bacteria to ampicillin, cephalotin, cefotaxime, cefoxitin, tetracycline, chloramphenicol and gentamicin was tested by the standard disk diffusion technique. The most effective antibiotic against S. aureus was chloramphenicol (78%) followed by gentamicin (63%) and tetracycline (57%); against E. coli cefotaxime (82%) followed by cefoxitin (77%), cephalitin (62%) and chloramphenicol (53%); against Klebsiella cefotaxime (95%) followed by chloramphenicol (90%), tetracycline (70%), cephalotin and gentamicin (each 66%); and cefoxitin (60%); against P. aeruginosa cefotaxime (56%), gentamicin (33%) and chloramphenicol (29%).
authors.affiliation: Department of Biological Sciences, Yarmouk University, Irbid-Jordan.
authors.forename: M J
authors.initials: MJ
authors.lastname: Abussaud
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003428:Cross Infection / Q000453:epidemiology*; D004926:Escherichia coli / Q000187:drug effects / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D015994:Incidence; D007362:Intensive Care Units; D015278:Intensive Care Units, Pediatric; D007709:Klebsiella / Q000187:drug effects / Q000302:isolation & purification; D007710:Klebsiella Infections / Q000453:epidemiology* / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D011552:Pseudomonas Infections / Q000453:epidemiology* / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000302:isolation & purification; D012529:Saudi Arabia / Q000453:epidemiology; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification; D013503:Surgery Department, Hospital; D014946:Wound Infection / Q000453:epidemiology*
chemical_list: D000900:Anti-Bacterial Agents