Facial heliotrope rash as the initial manifestation of acute myelomonocytic leukemia.
The association of leukocytoclastic vasculitis or dermatomyositis with malignancies has been reported. We describe a patient who developed a skin rash, histologically compatible with dermatomyositis, which during the course of the disease switched to leukocytoclastic vasculitis, which was accompanied with peripheral blood pancytopenia in the absence of any specific pathological manifestation from the bone marrow three years prior to the diagnosis of acute myelomonocytic leukemia (AMML).
Tzavara
V
V
Department of Pathophysiology, Medical School, National University of Athens, Laikon General Hospital, Greece.
Stamoulis
K
K
Aroni
K G
KG
Kordossis
T
T
Boki
K A
KA
D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use; D000971:Antineoplastic Combined Chemotherapy Protocols; D001168:Arthritis / Q000150:complications; D001853:Bone Marrow / Q000473:pathology; D003561:Cytarabine / Q000627:therapeutic use; D003872:Dermatitis / Q000150:complications* / Q000188:drug therapy; D005145:Face / Q000473:pathology; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D006801:Humans; D007642:Keratosis; D015479:Leukemia, Myelomonocytic, Acute / Q000150:complications* / Q000188:drug therapy*; D008297:Male; D008942:Mitoxantrone / Q000627:therapeutic use; D010198:Pancytopenia / Q000150:complications / Q000188:drug therapy; D010306:Parotid Gland / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use
D000964:Antimetabolites, Antineoplastic; D003561:Cytarabine; D016179:Granulocyte Colony-Stimulating Factor; D011239:Prednisolone; D008942:Mitoxantrone