title: Emergence of a methicillin-resistant Staphylococcus aureus clone related to the Brazilian epidemic clone III::B:A causing invasive disease among AIDS patients in a Brazilian hospital.
abstract: In a previous study we described the extensive geographic spread of a multidrug-resistant methicillin-resistant Staphylococcus aureus (MRSA) clone in hospitals located in the southern, southeastern, and northern parts of Brazil. In this study we used a set of molecular markers to demonstrate the emergence of a novel MRSA clone distinct from but closely related to the widely spread Brazilian epidemic clone. The new MRSA clone caused an outbreak among acquired immunodeficiency syndrome patients in a Brazilian hospital specializing in tropical diseases and human immunodeficiency virus- and human T-cell leukemia virus (HLTV)-related infections.
authors.affiliation: Rockefeller University, New York, New York 10021, USA.
authors.forename: L A
authors.initials: LA
authors.lastname: Teixeira
authors.forename: M C
authors.initials: MC
authors.lastname: Lourenço
authors.forename: A M
authors.initials: AM
authors.lastname: Figueiredo
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D001426:Bacterial Proteins / Q000235:genetics; D001938:Brazil / Q000453:epidemiology; D003001:Cloning, Molecular; D004591:Electrophoresis, Polyacrylamide Gel; D005798:Genes, Bacterial; D005838:Genotype; D006801:Humans; D016106:Methicillin Resistance / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D017720:Molecular Epidemiology; D011110:Polymorphism, Genetic / Q000235:genetics; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000235:genetics
chemical_list: D001426:Bacterial Proteins