Oxazolidinones: new antibacterial agents.
The oxazolidinones are a new chemical class of synthetic antibacterial agents that are active orally or intravenously against multidrug-resistant Gram-positive bacteria. Their unique mechanism of action and activity against bacteria that pose therapeutic problems in hospital and community treatments make them promising candidates for antimicrobial agents.
Ford
C W
CW
Pharmacia & Upjohn Inc., Kalamazoo, MI 49001, USA.
Hamel
J C
JC
Stapert
D
D
Moerman
J K
JK
Hutchinson
D K
DK
Barbachyn
M R
MR
Zurenko
G E
GE
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects*; D001424:Bacterial Infections / Q000188:drug therapy; D017714:Community-Acquired Infections / Q000188:drug therapy; D003428:Cross Infection / Q000188:drug therapy; D006801:Humans; D010080:Oxazoles / Q000494:pharmacology*; D023303:Oxazolidinones; D010403:Penicillin Resistance
D000900:Anti-Bacterial Agents; D010080:Oxazoles; D023303:Oxazolidinones; C054755:4-acetylphenyloxooxazolidinylmethylacetamide