Is Parkinson's disease inherited?
There has been considerable uncertainty as to whether idiopathic Parkinson's disease may be inherited except in a few rare instances. The evidence for and against inheritance is reviewed. The recent discovery of genetic linkage to chromosome 4q in a large Italian pedigree with parkinsonism has shed new light on this problem.
Hawkes
C H
CH
Department of Neurology, Leeds General Infirmary.
D000483:Alleles; D001057:Apolipoproteins E / Q000235:genetics; D002894:Chromosomes, Human, Pair 4; D004200:Diseases in Twins / Q000235:genetics; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D010300:Parkinson Disease / Q000453:epidemiology / Q000235:genetics*; D015995:Prevalence; D018433:Twin Studies as Topic
D001057:Apolipoproteins E; D005819:Genetic Markers