[Undifferentiated soft tissue tumor with rhabdoid phenotype (extra-renal rhabdoid tumor). Report of a congenital case associated with medulloblastoma in a brother].
We report a case of congenital cervical rhabdoid tumor with association of a medulloblastoma in a brother. The immunohistochemical features of this tumor are compatible with a neuroectodermal differentiation (MIC 2+, Leu 7+). Extrarenal rhabdoid tumors share a common morphology but do not represent a single entity with only one histogenesis. Most of them are now considered to be of neuroectodermal origin. In our case, the association with a medulloblastoma in a brother seems to confirm this concept.
Costes
V
V
Service d'Anatomie Pathologique, CHU Gui de Chauliac, Montpellier.
Medioni
D
D
Durand
L
L
Sarran
N
N
Marguerite
G
G
Baldet
P
P
D002454:Cell Differentiation / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008527:Medulloblastoma / Q000235:genetics / Q000473:pathology*; D009333:Neck; D010641:Phenotype; D018335:Rhabdoid Tumor / Q000151:congenital / Q000235:genetics / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000151:congenital / Q000235:genetics / Q000473:pathology*
Tumeur indifférenciée des tissus mous avec phénotype rhabdoïde (tumeur rhabdoïde extra-rénale). A propos d'un cas congénital associé à un médulloblastome dans la fratrie.