title: Course and outcome in adolescent anorexia nervosa.
abstract: OBJECTIVE
  To investigate course, outcome, and psychiatric comorbidity in adolescent anorexia nervosa by repeated follow-up assessment.
  
  
  METHODS
  Thirty-four subjects (88%) of an original sample of 39 inpatients were followed up personally 3 and 7 years after discharge and classified according to DSM-III-R eating disorder categories. Standardized psychometric instruments were used to assess specific eating disorder symptoms, concomitant general psychopathology, and comorbid psychiatric diagnoses.
  
  
  RESULTS
  After 7 years, 1 patient (3%) had anorexia nervosa, 4 patients (12%) bulimia nervosa, and 10 patients (29%) eating disorder not otherwise specified (EDNOS). Anxiety disorders (41%) and affective disorders (18%) were the most prevalent comorbid psychiatric disorders. Concomitant general psychopathology was significantly related to the outcome of the eating disorder.
  
  
  CONCLUSIONS
  According to our results, the majority of former adolescent anorexic inpatients had shown substantial improvement in their eating disorders symptomatology after 7 years. Patients with persisting eating disorders mostly suffered from restrictive symptoms. The prevalence and distribution of psychiatric comorbidity were similar to those of adult-onset anorexia nervosa. Subjects with a worse outcome of the eating disorder also displayed higher levels of general psychopathology.
authors.affiliation: Department of Child and Adolescent Psychiatry, Philipps University, Marburg, Germany.
authors.forename: B M
authors.initials: BM
authors.lastname: Herpertz-Dahlmann
authors.forename: C
authors.initials: C
authors.lastname: Wewetzer
authors.forename: E
authors.initials: E
authors.lastname: Schulz
authors.forename: H
authors.initials: H
authors.lastname: Remschmidt
mesh_terms: D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000175:diagnosis* / Q000523:psychology / Q000628:therapy; D001008:Anxiety Disorders / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D002032:Bulimia / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D002648:Child; D015897:Comorbidity; D003866:Depressive Disorder / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D016896:Treatment Outcome