title: Rapid diagnosis of Legionella pneumophila serogroup 1 infection with the Binax enzyme immunoassay urinary antigen test.
abstract: The Binax legionella urinary antigen (LUA) enzyme immunoassay (Binax, Portland, Maine) was evaluated in 159 patients with suspected or proven legionellosis and 209 controls. A positive LUA test was found in 37% of patients with suspected legionellosis overall and in 83% of those with proven Legionella pneumophila serogroup 1 infection. The sensitivity of the LUA test was significantly greater than that of the direct fluorescent-antigen test (83 versus 42%; P < 0.0001) but not significantly different from that of culture (85%) or serology (91%); specificity was at least 99.5%.
authors.affiliation: Department of Clinical Microbiology, Westmead Hospital, Sydney, New South Wales, Australia.
authors.forename: D
authors.initials: D
authors.lastname: Kazandjian
authors.forename: R
authors.initials: R
authors.lastname: Chiew
authors.forename: G L
authors.initials: GL
authors.lastname: Gilbert
mesh_terms: D000942:Antigens, Bacterial / Q000032:analysis / Q000276:immunology; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D016952:Legionella pneumophila / Q000276:immunology / Q000302:isolation & purification*; D007877:Legionnaires' Disease / Q000175:diagnosis* / Q000382:microbiology
chemical_list: D000942:Antigens, Bacterial