title: Chinese herbs and warfarin potentiation by 'danshen'.
abstract: Drug interactions with warfarin can be dangerous and although common drug interactions are now well recognized those with Chinese herbs are not widely appreciated. 'Danshen' is a herbal medicine often used for various complaints, particularly cardiovascular, in the Chinese community. We report a case of danshen-induced overcoagulation with severe and dangerous abnormalities of clotting in a patient with rheumatic heart disease.
authors.affiliation: Department of Medicine, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong.
authors.forename: C M
authors.initials: CM
authors.lastname: Yu
authors.forename: J C
authors.initials: JC
authors.lastname: Chan
authors.forename: J E
authors.initials: JE
authors.lastname: Sanderson
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects* / Q000627:therapeutic use; D001780:Blood Coagulation Tests; D004338:Drug Combinations; D004357:Drug Synergism; D004365:Drugs, Chinese Herbal / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D010618:Phenanthrolines / Q000009:adverse effects* / Q000627:therapeutic use; D010936:Plant Extracts; D027561:Salvia miltiorrhiza; D014859:Warfarin / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D010618:Phenanthrolines; D010936:Plant Extracts; C028972:dan-shen root extract; D014859:Warfarin