Light microscopic comparison of the patterns of glutamate-like and homocysteate-like immunoreactivities in rat dorsal lateral geniculate after combined visual cortical and retinal ablations.
To study the contribution of retinal and cortical afferents to the patterns of glutamate- and homocysteate-like immunoreactivities in dorsal lateral geniculate, combined retinal and cortical ablations were performed in rats. In controls, glutamate immunoreactivity was in terminal-like dots and neurons. Homocysteate immunoreactivity was in small puncta. In lesioned animals, most glutamate-immunoreactive dots disappeared. In contrast, abundant puncta resembling parts of glial cells were immunoreactive for homocysteate.
Grandes
P
P
Department of Neurosciences, Faculty of Medicine and Dentistry, Basque Country University, Bilbao, Spain.
Mateos
J M
JM
Azkue
J
J
Sarría
R
R
Cuénod
M
M
Streit
P
P
D000818:Animals; D005829:Geniculate Bodies / Q000166:cytology / Q000378:metabolism*; D018698:Glutamic Acid / Q000378:metabolism*; D006651:Histocytochemistry; D006710:Homocysteine / Q000031:analogs & derivatives* / Q000378:metabolism; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012160:Retina / Q000502:physiology*; D016707:Tissue Fixation; D014793:Visual Cortex / Q000502:physiology*; D014795:Visual Pathways / Q000166:cytology / Q000502:physiology
D006710:Homocysteine; C007956:homocysteic acid; D018698:Glutamic Acid