Towards a unified model of tumor suppression: lessons learned from the human patched gene.
Dean
M
M
Human Genetics Section, Laboratory of Genomic Diversity, National Cancer Institute-Frederick Cancer Research and Development, MD 21702, USA. dean@fcrfv1.ncifcrf.gov
D000818:Animals; D002280:Basal Cell Carcinoma / Q000235:genetics; D029721:Drosophila Proteins; D016147:Genes, Tumor Suppressor; D019476:Insect Proteins; D008565:Membrane Proteins / Q000235:genetics; D009369:Neoplasms / Q000209:etiology*; D009857:Oncogenes; D000072079:Patched Receptors; D011956:Receptors, Cell Surface; D015398:Signal Transduction; D016212:Transforming Growth Factor beta / Q000235:genetics
D029721:Drosophila Proteins; D019476:Insect Proteins; D008565:Membrane Proteins; D000072079:Patched Receptors; D011956:Receptors, Cell Surface; D016212:Transforming Growth Factor beta; C064196:dpp protein, Drosophila