title: Deadly conformations--protein misfolding in prion disease.
authors.affiliation: Department of Genetics and Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
authors.forename: A L
authors.initials: AL
authors.lastname: Horwich
authors.forename: J S
authors.initials: JS
authors.lastname: Weissman
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D006801:Humans; D066298:In Vitro Techniques; D008954:Models, Biological; D008958:Models, Molecular; D008969:Molecular Sequence Data; D018621:PrPC Proteins / Q000737:chemistry / Q000235:genetics / Q000472:pathogenicity; D018620:PrPSc Proteins / Q000737:chemistry / Q000235:genetics / Q000472:pathogenicity; D017096:Prion Diseases / Q000209:etiology* / Q000378:metabolism / Q000635:transmission; D011328:Prions / Q000737:chemistry* / Q000235:genetics / Q000472:pathogenicity*; D011487:Protein Conformation; D013045:Species Specificity
chemical_list: D018621:PrPC Proteins; D018620:PrPSc Proteins; D011328:Prions