[Effect of ethanol, diazepam, and reserpine on the activity of angiotensin-converting enzyme and carboxypeptidase in normal state and during stress].
There was discovered a resemblance in the influence of some pharmacological agents such as ethanol, diazepam and rezerpine on the activity of enzymes of metabolism of biological active peptides in the blood under emotional stress. It was determined that the character of the influence depends on the emotional status of animals. The possibility of drawing both angiotensin converting enzyme and carboxypeptidase N in the stress-protection action of the ethanol, diazepam and rezerpine is discussed.
Vernigora
A N
AN
Nikishin
N N
NN
Gengin
M T
MT
D000806:Angiotensin-Converting Enzyme Inhibitors / Q000494:pharmacology; D000818:Animals; D002268:Carboxypeptidases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D003975:Diazepam / Q000494:pharmacology*; D004789:Enzyme Activation; D004791:Enzyme Inhibitors / Q000494:pharmacology; D000431:Ethanol / Q000494:pharmacology*; D008297:Male; D007703:Peptidyl-Dipeptidase A / Q000378:metabolism*; D051381:Rats; D012110:Reserpine / Q000494:pharmacology*; D013315:Stress, Psychological / Q000201:enzymology* / Q000517:prevention & control
D000806:Angiotensin-Converting Enzyme Inhibitors; D004791:Enzyme Inhibitors; D000431:Ethanol; D012110:Reserpine; D002268:Carboxypeptidases; D007703:Peptidyl-Dipeptidase A; D003975:Diazepam
Vliianie étanola, diazepama i rezerpina na aktivnost' angiotenzinprevrashchaiushchego fermenta i karboksipeptidazy v norme i pri stress.