Epstein-Barr virus encephalomyelitis diagnosed by polymerase chain reaction: detection of the genome in the CSF.
A case of encephalomyelitis with polymerase chain reaction detection of Epstein-Barr virus (EBV) in the CSF, and concurrent serologic changes consistent with acute systemic EBV infection is presented and discussed. We document involvement of the brain, spinal cord, and nerve roots, summarize some unusual imaging findings, and note the evolution of CSF oligoclonal bands.
Tselis
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A
Department of Neurology, Wayne State University School of Medicine, Detroit Medical Center, MI 48201, USA.
Duman
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R
Storch
G A
GA
Lisak
R P
RP
D000328:Adult; D001921:Brain / Q000473:pathology; D004679:Encephalomyelitis / Q000134:cerebrospinal fluid* / Q000175:diagnosis / Q000821:virology*; D016679:Genome, Viral; D004854:Herpesvirus 4, Human; D006801:Humans; D007244:Infectious Mononucleosis; D008279:Magnetic Resonance Imaging; D008297:Male; D016133:Polymerase Chain Reaction; D012698:Serologic Tests; D013116:Spinal Cord / Q000473:pathology; D013126:Spinal Nerve Roots / Q000473:pathology