title: Textured surface silicone breast implants: histology in the human.
abstract: Previous studies on the interaction of textured silicone breast implants has analyzed tissue expanders or used animal models. To date, the data on long-term results of the textured silicone breast implants have not examined permanent implants or in vivo effects in the human. A prospective study was designed to examine the interaction of textured silicone breast implants in a human over several years. A single surgeon, standard surgical technique, and single-type implant design were included. The results revealed 78% had silicone particles in the tissue immediately adjacent to the implant interface. No distant migration, metaplasia, or adverse effects were noted. Our results indicate that silicone fragmentation is common but appears to be confined to the local environment.
authors.forename: C B
authors.initials: CB
authors.lastname: Lesesne
mesh_terms: D000328:Adult; D001706:Biopsy; D001940:Breast / Q000648:ultrastructure; D018427:Breast Implants; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D012828:Silicones
chemical_list: D012828:Silicones