Cortical development: layers of complexity.
Studies of spontaneous mutant mice with neurological phenotypes, particularly the cloning and analysis of the genes responsible, are shedding light on the complex processes that lead to formation of the deceptively simple layered structure of the cerebral cortex.
Gilmore
E C
EC
Department of Neuroscience, Case Western Reserve Medical School, 10900 Euclid Avenue, Cleveland, Ohio 44106, USA.
Herrup
K
K
D000818:Animals; D002540:Cerebral Cortex / Q000002:abnormalities / Q000033:anatomy & histology* / Q000196:embryology; D003001:Cloning, Molecular; D005314:Embryonic and Fetal Development; D018507:Gene Expression Regulation, Developmental; D051379:Mice; D008818:Mice, Neurologic Mutants; D009474:Neurons / Q000166:cytology*