The use of oral terbinafine (Lamisil) in children.
In an ongoing study of Lamisil in children, 21 patients have so far been enrolled and preliminary data are reported in this paper. Eighteen have tinea capitis and 1 has tinea corporis. So far, Trichophyton tonsurans has been identified in 17 and Trichophyton violaceum in 2. Lamisil has so far proved to be well tolerated, efficacious and cost-effective in a 2-week course in those children with a Trichophyton species. If Microsporum canis is isolated, a longer course is probably indicated. Lamisil has the distinct advantage of producing good results in a short time period, making patient compliance less of a problem.
Krafchik
B
B
Department of Dermatology, Hospital for Sick Children, Toronto, Canada. bernice.Krafchic@mailhub.sickkids.on.ca
Pelletier
J
J
D000284:Administration, Oral; D000935:Antifungal Agents / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009281:Naphthalenes / Q000008:administration & dosage*; D000077291:Terbinafine; D014005:Tinea / Q000188:drug therapy / Q000382:microbiology; D014006:Tinea Capitis / Q000188:drug therapy* / Q000382:microbiology; D016896:Treatment Outcome
D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine