title: Validity of the 13-C-urea breath test for the diagnosis of Helicobacter pylori infection.
abstract: Infection with Helicobacter pylori (H. pylori) plays an important role in the pathogenesis of gastritis, peptic ulcer and gastric cancer, and the 13C-urea breath test (13C-UBT) is a convenient and non-invasive method for the detection of H. pylori in the stomach. We have examined the sensitivity, specificity and accuracy of 13C-UBT. The 13CO2/12CO2 ratio was measured using infrared spectroscopy (IR) and gas chromatography/mass spectrometry (GC-MS).
authors.affiliation: Dept. of Medicinal Chemistry, Meiji College of Pharmacy, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kajiwara
authors.forename: K
authors.initials: K
authors.lastname: Iida
authors.forename: K
authors.initials: K
authors.lastname: Takatori
authors.forename: Y
authors.initials: Y
authors.lastname: Taniguchi
authors.forename: K
authors.initials: K
authors.lastname: Kimura
mesh_terms: D001944:Breath Tests / Q000379:methods; D008401:Gas Chromatography-Mass Spectrometry; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori; D006801:Humans; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013055:Spectrophotometry, Infrared