title: [Elaboration and improvement of biochemical methods in early diagnosis and prognostication of the development of occupational diseases].
abstract: The article summarizes and analyzes scientific and practical studies conducted by Laboratory Department of Moscow Erisman Hygienic Research Institute. The theoretic works described resorption of Metallic ions from digestive tract into the blood, revealed mathematic dependence of resorption coefficient on ion radius and potential, hydration heat, solubility and other physical and chemical parameters. The scientists developed basic requirements for hazards detection in human biologic material during hygienic and toxicologic clinical investigations. A suggested bunch of biochemical and immunologic methods helps in early and differential diagnosis of respiratory diseases caused by dust. Refinements in some biochemical and toxicologic chemical methods enable to improve metrological characteristics, reduce reagents amount, simplify the methods.
authors.forename: N A
authors.initials: NA
authors.lastname: Pavlovskaia
authors.forename: N I
authors.initials: NI
authors.lastname: Danilova
mesh_terms: D000395:Air Pollutants, Occupational / Q000032:analysis*; D001991:Bronchitis / Q000175:diagnosis / Q000209:etiology; D002908:Chronic Disease; D003124:Colorimetry; D003937:Diagnosis, Differential; D004391:Dust / Q000009:adverse effects*; D006801:Humans; D008962:Models, Theoretical; D009784:Occupational Diseases / Q000097:blood / Q000175:diagnosis* / Q000652:urine; D011048:Polarography; D011199:Potentiometry; D011379:Prognosis; D012140:Respiratory Tract Diseases / Q000097:blood / Q000175:diagnosis* / Q000652:urine; D012680:Sensitivity and Specificity; D013997:Time Factors
chemical_list: D000395:Air Pollutants, Occupational; D004391:Dust
vernacular_title: Razrabotka i usovershenstvovanie biokhimicheskikh metodov ranneĭ diagnostiki i prognozirovaniia razvitiia profzabolevaniĭ.