title: [Possible use of erythrocyte antioxidant enzymes as markers of the course of disease in patients with hemoblastoses].
abstract: Blood and erythrocytes of 50 healthy volunteers and 105 patients with different forms of hemoblastoses were investigated. 54 patients had acute phase, 51 patients--remission stage of disease. Essential differences in the activity of antioxidant enzymes (SOD, CAT, GSH-Px) were detected and compared with content of MDA and degree of anaemia. Acute phase had more significantly alteration of antioxidant defence: diverse changes of the activity of SOD and CAT, significantly inhibition of GSH-Px, the high level of MDA and increased degree of anaemia.
authors.forename: A O
authors.initials: AO
authors.lastname: Kumerova
authors.forename: V I
authors.initials: VI
authors.lastname: Petukhov
authors.forename: A P
authors.initials: AP
authors.lastname: Shkesters
authors.forename: A A
authors.initials: AA
authors.lastname: Silova
authors.forename: A G
authors.initials: AG
authors.lastname: Letse
mesh_terms: D000328:Adult; D000368:Aged; D002374:Catalase / Q000097:blood*; D004796:Clinical Enzyme Tests; D004912:Erythrocytes / Q000201:enzymology*; D005979:Glutathione Peroxidase / Q000097:blood; D019337:Hematologic Neoplasms / Q000175:diagnosis*; D006801:Humans; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D011379:Prognosis; D013482:Superoxide Dismutase / Q000097:blood*
chemical_list: D008315:Malondialdehyde; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase
vernacular_title: Vozmozhnost' ispol'zovaniia antioksidantnykh fermentov éritrotsitov v kachestve indikatorov, kharakterizuiushchikh techenie bolezni u bol'nykh gemoblastozami.