title: Nationwide survey of neurologic manifestations of acquired immunodeficiency syndrome in Japan.
abstract: To study the epidemiology of the neurologic manifestations of human immunodeficiency virus (HIV)-1 infection in Japan, we conducted two nationwide surveys. Of 1854 HIV-1 carriers, 578 had acquired immunodeficiency syndrome (AIDS) and 166 (28.7% of AIDS patients) had neurologic manifestations including HIV dementia (11.8%), myelopathy (3.6%) and peripheral neuropathy (2.6%). The incidence of neurologic manifestations in patients with HIV-1 infection through blood products was about 60% of that in patients with HIV-1 infection through sex or unknown routes. This nationwide survey showed that the incidence of neurologic manifestations in AIDS patients in Japan was consistent with that in other countries.
authors.affiliation: Third Department of Internal Medicine, Kagoshima University School of Medicine.
authors.forename: M
authors.initials: M
authors.lastname: Nakagawa
authors.forename: Y
authors.initials: Y
authors.lastname: Maruyama
authors.forename: H
authors.initials: H
authors.lastname: Sugita
authors.forename: M
authors.initials: M
authors.lastname: Osame
mesh_terms: D015526:AIDS Dementia Complex / Q000453:epidemiology* / Q000209:etiology; D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology* / Q000209:etiology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications / Q000453:epidemiology*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000453:epidemiology*; D015497:HIV-1; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009422:Nervous System Diseases / Q000453:epidemiology* / Q000209:etiology