Successful clinical use of a plasma-derived, dual virus inactivated factor VII concentrate incorporating solvent-detergent and dry heat treatment.
Smith
M P
MP
Rice
K M
KM
Savidge
G F
GF
D000293:Adolescent; D000328:Adult; D000368:Aged; D001769:Blood / Q000187:drug effects / Q000821:virology; D002648:Child; D003902:Detergents / Q000494:pharmacology; D004341:Drug Evaluation; D005169:Factor VIII / Q000276:immunology / Q000302:isolation & purification* / Q000627:therapeutic use; D005612:Freeze Drying; D006467:Hemophilia A / Q000188:drug therapy* / Q000276:immunology; D006507:Hepatovirus / Q000187:drug effects / Q000302:isolation & purification; D006358:Hot Temperature; D006801:Humans; D007518:Isoantibodies / Q000096:biosynthesis / Q000276:immunology; D008875:Middle Aged; D010755:Organophosphates / Q000494:pharmacology; D017993:Parvovirus, Canine / Q000187:drug effects / Q000302:isolation & purification; D011136:Polysorbates / Q000494:pharmacology; D012449:Safety; D012997:Solvents / Q000494:pharmacology; D014777:Virus Diseases / Q000517:prevention & control
D003902:Detergents; D007518:Isoantibodies; D010755:Organophosphates; D011136:Polysorbates; D012997:Solvents; D005169:Factor VIII; C009524:tributyl phosphate