title: Grapefruits and drugs: when is statistically significant clinically significant?
authors.forename: D R
authors.initials: DR
authors.lastname: Abernethy
mesh_terms: D000818:Animals; D001189:Aryl Hydrocarbon Hydroxylases; D001628:Beverages; D002957:Citrus; D051544:Cytochrome P-450 CYP3A; D003577:Cytochrome P-450 Enzyme System / Q000378:metabolism; D015736:Felodipine / Q000097:blood / Q000493:pharmacokinetics; D006801:Humans; D008657:Metabolic Clearance Rate; D009543:Nifedipine / Q000097:blood / Q000493:pharmacokinetics; D010089:Oxidoreductases, N-Demethylating / Q000378:metabolism; D010599:Pharmacokinetics; D012907:Smoking
chemical_list: D003577:Cytochrome P-450 Enzyme System; D001189:Aryl Hydrocarbon Hydroxylases; D051544:Cytochrome P-450 CYP3A; D010089:Oxidoreductases, N-Demethylating; D009543:Nifedipine; D015736:Felodipine