title: Comparison of unilateral arytenoid lateralization and ventral ventriculocordectomy for the treatment of experimentally induced laryngeal paralysis in dogs.
abstract: This study evaluated changes in respiratory function in dogs with experimentally induced laryngeal paralysis treated with either unilateral arytenoid lateralization or ventral ventriculocordectomy, and compared the effectiveness of these procedures. Evaluation consisted of clinical assessment and tidal breathing flow volume loop and upper airway resistance measurements. Carbon dioxide and doxapram hydrochloride were used as respiratory stimulants. Initially, all dogs improved clinically after corrective surgery. However, by the end of the study, laryngeal collapse had developed in 2 of 5 dogs corrected by ventral ventriculocordectomy. No statistical differences in upper airway mechanics testing were seen between the surgical procedures. With both groups combined, many measurements of upper airway obstruction improved after surgical correction. Based on this study, these surgical procedures yield comparable results, although additional studies are needed to evaluate both the cause of laryngeal collapse and the role of upper airway mechanics testing in the evaluation of canine laryngeal paralysis.
authors.affiliation: Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana 61820, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Alsup
authors.forename: C L
authors.initials: CL
authors.lastname: Greenfield
authors.forename: L L
authors.initials: LL
authors.lastname: Hungerford
authors.forename: B C
authors.initials: BC
authors.lastname: McKiernan
authors.forename: H E
authors.initials: HE
authors.lastname: Whiteley
mesh_terms: D000818:Animals; D002245:Carbon Dioxide / Q000494:pharmacology; D004283:Dog Diseases / Q000601:surgery*; D004285:Dogs; D004315:Doxapram / Q000494:pharmacology; D007828:Laryngoscopy; D011184:Postoperative Period; D012119:Respiration / Q000187:drug effects; D019141:Respiratory System Agents / Q000494:pharmacology; D014826:Vocal Cord Paralysis / Q000601:surgery / Q000662:veterinary*
chemical_list: D019141:Respiratory System Agents; D002245:Carbon Dioxide; D004315:Doxapram