Pleomorphic medium-sized T-cell lymphoma following Hodgkin's disease (nodular sclerosis type).
We describe a 32-year-old woman who presented with Hodgkin's disease, nodular sclerosis type II, subtype I, which necessitated several treatments over 11 years. The patient then developed pleomorphic, medium-sized T-cell lymphoma, which had a fatal outcome within 13 months. The role of radiotherapy, splenectomy, and chemotherapy in second tumor induction is compared with other sequential T-cell lymphomas. The significance of rare Epstein-Barr virus-infected cells during the T-cell lymphoma extension is discussed.
Gaulier
A
A
Service d'Anatomie Pathologique, Hôpital V. Dupouy, Argenteuil, France.
Teillet
F
F
Davi
F
F
Couturier
J
J
Laye
S
S
Raphael
M
M
D000328:Adult; D005260:Female; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008228:Lymphoma, Non-Hodgkin / Q000473:pathology*; D016399:Lymphoma, T-Cell / Q000473:pathology*; D016609:Neoplasms, Second Primary / Q000473:pathology*; D012598:Sclerosis