title: Role of redchilli (Capsaicin) in the formation of colonic carcinoma.
abstract: The effect of feeding redchilli (Capsaicin) powder on the histopathological changes occurring in the colonic mucosa was studied in rats. These animals were compared with those treated with a colonic carcinogen 1,2-dimethylhydrazine (DMH). Animals fed with redchilli, dimethylhydrazine, dimethylhydrazine plus redchilli powder showed polyp and dysplasia, malignant tumour and malignant tumour with transitional area of dysplasia.
authors.affiliation: Department of Biochemistry, Faculty of Medicine, Annamalai University, Tamil Nadu, India.
authors.forename: S
authors.initials: S
authors.lastname: Chitra
authors.forename: P
authors.initials: P
authors.lastname: Viswanathan
authors.forename: N
authors.initials: N
authors.lastname: Nalini
authors.forename: K
authors.initials: K
authors.lastname: Sabitha
authors.forename: V P
authors.initials: VP
authors.lastname: Menon
mesh_terms: D019813:1,2-Dimethylhydrazine; D000818:Animals; D002277:Carcinoma / Q000209:etiology* / Q000473:pathology; D003108:Colonic Diseases / Q000209:etiology* / Q000473:pathology; D003110:Colonic Neoplasms / Q000209:etiology* / Q000473:pathology; D004127:Dimethylhydrazines / Q000009:adverse effects*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D017365:Spices / Q000009:adverse effects*
chemical_list: D004127:Dimethylhydrazines; D019813:1,2-Dimethylhydrazine