[Dynamics of changes in the concentration of thyroid hormones in in rat blood after subtotal thyroidectomy, internal, or external irradiation].
Thyroidectomy or administration of high activities (> 1.1 Mbq) of 131I to rats causes initial decrease in blood concentration of thyroid hormones which returns to the normal level. Administration of lower doses (< 1.1 Mbq) of radioactive iodine or external radiation (1, 3, 6 Gr) did not cause similar changes. Data obtained that: 1) thyroid gland is relatively radioresistant organ with high reparative function after surgical or radioactive damage; 2) alterations of thyroid status after the external radiation are not related to a direct action of radiation on the thyroid gland.
Shkumatov
L M
LM
Krylova
I M
IM
Markova
A G
AG
Bagel'
I M
IM
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D007457:Iodine Radioisotopes; D051381:Rats; D013961:Thyroid Gland / Q000528:radiation effects*; D013965:Thyroidectomy; D013974:Thyroxine / Q000097:blood*; D014284:Triiodothyronine / Q000097:blood*; D014916:Whole-Body Irradiation
D007457:Iodine Radioisotopes; D014284:Triiodothyronine; D013974:Thyroxine
Dinamika izmeneniĭ kontsentratsii tireoidnykh gormonov v krovi krys posle subtotal'noĭ tireoidéktomii, vnutrennego ili vneshnego oblucheniia.