Concurrence of multiple sclerosis and brain tumor: clinical considerations.
We report a patient with multiple sclerosis (MS) who developed an oligodendroglioma 8 years after the initial diagnosis of MS. This is the first description of a neoplasm, suspected initially on brain MRI and subsequently confirmed by brain biopsy, in an MS patient. Our case emphasizes the need to evaluate atypical brain MRI lesions carefully, even in well-established MS patients, as well as to obtain a tissue diagnosis of such lesions whenever possible in order to determine their precise etiology.
Khan
O A
OA
Department of Neurology, University of Maryland School of Medicine, Baltimore 21201, USA.
Bauserman
S C
SC
Rothman
M I
MI
Aldrich
E F
EF
Panitch
H S
HS
D000328:Adult; D001706:Biopsy; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000150:complications*; D009837:Oligodendroglioma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology