[The diagnosis of chronic dust-induced bronchitis].
In dust-induced bronchitis, alterations in the pulmonary parenchyma present themselves in the main cellular indices for bronchioalveolar lavage (BAL), thought to be of much importance to its diagnosis. A total of 53 patients with initial and manifest forms of dust bronchitis underwent BAL. There has been found the following: a decrease in the mononuclear phagocyte system cells (MPhS) reflecting the state of local cellular immunity; rise in the amounts of coniophages, suggesting phagocytic activity of alveolar macrophages (AM) and dust blockade of MPhS cells; emergence and augmentation of counts of gigantic Pirogov-Langhans' cells characteristic of tuberculous granulomas, and also decrease in the counts of lymphocytes. There is a striking decrement in the vitality of AM, with polycytosis being commonly seen. Detection of granular forms of Mycobacterium tuberculosis in BAL and Pirogov-Langhans' cells enables a major proportion of "dust-induced bronchitis" to be considered as belonging to the silicotuberculous process.
Filipchenko
L L
LL
Slinchenko
N Z
NZ
Sidorenko
O N
ON
D001991:Bronchitis / Q000175:diagnosis* / Q000209:etiology / Q000276:immunology; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology / Q000382:microbiology; D001999:Bronchoscopy; D002908:Chronic Disease; D004391:Dust / Q000009:adverse effects*; D006801:Humans; D007111:Immunity, Cellular; D016676:Macrophages, Alveolar / Q000276:immunology; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D012830:Silicotuberculosis / Q000175:diagnosis
D004391:Dust
Diagnostika khronicheskogo pylevogo bronkhita.