Cyclic peptides from higher plants. 34. Segetalins G and H, structures and estrogen-like activity of cyclic pentapeptides from Vaccaria segetalis.
Segetalins G and H (1-2) possessing estrogen-like activity are cyclic pentapeptides from the seeds of Vaccaria segetalis. Their structures, cyclo(-Gly-Ala-Lys-Tyr-Val) (1) and cyclo(-Gly-Phe-Ser-Tyr-Arg-) (2), were determined by interpretation of spectral data.
Yun
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Department of Pharmacognosy, Tokyo University of Pharmacy and Life Science, Japan.
Morita
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Takeya
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Itokawa
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D000818:Animals; D004967:Estrogens / Q000302:isolation & purification* / Q000494:pharmacology; D005260:Female; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D010052:Ovariectomy; D010456:Peptides, Cyclic / Q000302:isolation & purification* / Q000494:pharmacology; D011487:Protein Conformation; D051381:Rats; D017207:Rats, Sprague-Dawley; D012639:Seeds / Q000737:chemistry*; D014599:Uterus / Q000187:drug effects / Q000254:growth & development
D004967:Estrogens; D010456:Peptides, Cyclic; C105632:segetalin G; C105633:segetalin H