title: [The immunomorphology of the mucosa of the bronchi and gastroduodenal zone in children with combined disease of the bronchi and gastrointestinal tract].
abstract: Mucous membrane of the bronchi, antral zone of the stomach and duodenum were studied histologically, morphometrically, immunohistochemically and bacterioscopically in 47 children of 5 to 14 years of age with bronchial asthma (16 patients), obstructive bronchitis (12 patients), chronic pneumonia or chronic nonspecific bronchitis (19 patients). All these children had also gastroduodenitis. There was an increase of local production of IgE and enhanced degranulation of mast cells in bronchial mucosa and gastroduodenal zone in children with bronchial asthma and obstructive bronchitis. The proportion of CD4+/CD8+ decreased to 0.92 in bronchial asthma. Gastritis was associated much more frequently with Helicobacter pylori in children with chronic obstructive bronchitis and bronchial asthma.
authors.forename: A V
authors.initials: AV
authors.lastname: Novikova
authors.forename: E V
authors.initials: EV
authors.lastname: Klimanskaia
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Shershevskaia
authors.forename: S I
authors.initials: SI
authors.lastname: Erdes
authors.forename: V Kh
authors.initials: VKh
authors.lastname: Sosiura
authors.forename: E M
authors.initials: EM
authors.lastname: Taberovskaia
mesh_terms: D000293:Adolescent; D001706:Biopsy; D001980:Bronchi / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D001982:Bronchial Diseases / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D004386:Duodenum / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D005753:Gastric Mucosa / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D005767:Gastrointestinal Diseases / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D006801:Humans; D007136:Immunoglobulins / Q000378:metabolism; D007150:Immunohistochemistry; D007413:Intestinal Mucosa / Q000276:immunology* / Q000378:metabolism / Q000473:pathology; D009092:Mucous Membrane / Q000276:immunology / Q000378:metabolism / Q000473:pathology
chemical_list: D007136:Immunoglobulins
vernacular_title: Immunomorfologiia slizistoĭ obolochki bronkhov i gastroduodenal'noĭ zony u deteĭ pri sochetannom zabolevanii bronkhov i zheluduchno-kishechnogo trakta.