A series of 17 cases of congenital cystic adenomatoid malformation of the lung: management and outcome.
During a 5-year-period, 17 cases of congenital adenomatoid malformation of the lung were observed in the Department of Pediatric Surgery of Bologna University-S. Orsola-Malpighi Hospital; 16 cases were diagnosed in utero by ultra-sound. 13 patients had prenatal diagnosis between 21 and 23 weeks of gestation; 2 cases were diagnosed at 25 weeks and another one at 26 weeks. The other case came from another hospital, and the diagnosis was accidentally detected postnatally. In 3 cases the parents decided to terminate the pregnancy 3 cases had spontaneous improvement during the last weeks of gestation, and were perfectly normal at birth. One case was lost to follow-up; all remaining patients underwent resection. Among these patients only one was a nonsurvivor, while 9 have completely recovered. However, one patient developed persistent pulmonary hypertension, which could successfully be treated with drugs, another underwent laser treatment for laryngeal stenosis due to intubation. A special epidemiological information: 13 out 17 cases (76.5%) were female.
Cacciari
A
A
Department of Pediatric Surgery, University of Bologna, S. Orsola-Malpighi Hospital, Italy.
Ceccarelli
P L
PL
Pilu
G L
GL
Bianchini
M A
MA
Mordenti
M
M
Gabrielli
S
S
Milano
V
V
Zanetti
G
G
Pigna
A
A
Gentili
A
A
D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology; D007223:Infant; D053685:Laser Therapy; D008297:Male; D011247:Pregnancy; D011296:Prenatal Diagnosis; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014463:Ultrasonography