Fine-needle aspiration cytology of pleuropulmonary blastoma: case report and review of the literature.
This report describes the fine-needle aspiration (FNA) cytology of a case of pleuropulmonary blastoma in a 3-yr-9-mo-old male. Pleuropulmonary blastoma is considered by most authors to be distinct from pulmonary blastoma and is a rare malignant tumor of the intrathoracic cavity. FNA smears were cellular with numerous small ovoid to spindled cells with oval to elliptical nuclei exhibiting finely granular chromatin and inconspicuous nucleoli. The cytoplasm was scant and eosinophilic with indistinct borders. Focal chondroid material and blastema-like cells were noted. The differential diagnosis suggested by the cytologic findings included rhabdomysosarcoma, teratoma, neuroblastoma, malignant mesenchymoma, pleuropulmonary blastoma, and metastatic tumor. To our knowledge, this is the first report of the cytology of this tumor.
Gelven
P L
PL
Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston 29425, USA.
Hopkins
M A
MA
Green
C A
CA
Harley
R A
RA
Wilson
M M
MM
D000199:Actins / Q000032:analysis; D001707:Biopsy, Needle; D002675:Child, Preschool; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D010997:Pleural Neoplasms / Q000473:pathology*; D018202:Pulmonary Blastoma / Q000473:pathology*; D009418:S100 Proteins / Q000032:analysis; D014746:Vimentin / Q000032:analysis
D000199:Actins; D009418:S100 Proteins; D014746:Vimentin; D007633:Keratins