title: Concurrence of multiple sclerosis and brain tumor: clinical considerations.
abstract: We report a patient with multiple sclerosis (MS) who developed an oligodendroglioma 8 years after the initial diagnosis of MS. This is the first description of a neoplasm, suspected initially on brain MRI and subsequently confirmed by brain biopsy, in an MS patient. Our case emphasizes the need to evaluate atypical brain MRI lesions carefully, even in well-established MS patients, as well as to obtain a tissue diagnosis of such lesions whenever possible in order to determine their precise etiology.
authors.affiliation: Department of Neurology, University of Maryland School of Medicine, Baltimore 21201, USA.
authors.forename: O A
authors.initials: OA
authors.lastname: Khan
authors.forename: S C
authors.initials: SC
authors.lastname: Bauserman
authors.forename: M I
authors.initials: MI
authors.lastname: Rothman
authors.forename: E F
authors.initials: EF
authors.lastname: Aldrich
authors.forename: H S
authors.initials: HS
authors.lastname: Panitch
mesh_terms: D000328:Adult; D001706:Biopsy; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009103:Multiple Sclerosis / Q000150:complications*; D009837:Oligodendroglioma / Q000150:complications* / Q000175:diagnosis / Q000473:pathology