title: Relationship between lower-lip fistulae and cleft lip and/or palate in Von der Woude syndrome.
abstract: OBJECTIVE
  This study was conducted to evaluate the relationship between fistulae of the lower lip and cleft lip and/or palate in patients with Van der Woude syndrome.
  
  
  METHODS
  The medical records of 11,000 patients with cleft lip and/or palate registered at the Cleft Lip-Palate Research and Rehabilitation Hospital, University of São Paulo, Bauru were reviewed. Of these patients, 133 (1.2%) presented with Van der Woude syndrome.
  
  
  RESULTS
  Of the 133 patients, 88 (66.2%) exhibited full clefts, 22 (16.5%) only cleft lip, and 23 (17.3%) only cleft palate. The lower-lip fistulae observed in these 133 patients were bilateral symmetric in 66 (49.7%), bilateral asymmetric in 42 (31.6%), microform in 19 (14.3%), median in 5 (3.8%), and unilateral in 1 (0.7%).
  
  
  CONCLUSIONS
  This population sample appears to exhibit the previously published tendency for bilateral, unilateral, or mixed-type congenital fistulae to be associated with cleft lip with or without cleft palate, while so-called microforms or conic elevations are almost exclusively associated with cleft palate.
authors.affiliation: Department of Diagnosis and Surgery, Dental School of Araraquara, University of the State of São Paulo (UNESP), Brazil.
authors.forename: M A
authors.initials: MA
authors.lastname: Onofre
authors.forename: H B
authors.initials: HB
authors.lastname: Brosco
authors.forename: R
authors.initials: R
authors.lastname: Taga
mesh_terms: D002648:Child; D002971:Cleft Lip; D002972:Cleft Palate; D005260:Female; D005402:Fistula / Q000151:congenital*; D006801:Humans; D008047:Lip Diseases / Q000151:congenital*; D008297:Male; D012467:Salivary Gland Fistula / Q000151:congenital; D013577:Syndrome