title: Baker's pseudocyst in the prosthetic knee affected with aggressive granulomatosis caused by polyethylene wear.
abstract: It is our belief that this is the first histologically documented case of popliteal cyst secondary to early failure of a cementless knee prosthesis, that occurred after 4 years. The walls of the cyst presented with granulomatous reaction to polyethylene particles. In prosthetic reimplantation successive to excision of the cyst we observed a recurrence of cysts and osteointegration of the prosthetic components, that made reimplantation difficult. Histological assessment of the synovial tissue, periprosthetic tissue and underlying bone showed granulomatous reaction to polyethylene debris. A "tumor" in a patient that has a knee prosthesis can be caused by implant failure. In cases of early failure wear forms large particles and their migration at the bone-prosthesis interface may be obstructed and thus cause a different biological response. If reimplantation is necessary osteointegration of the implants may make surgery difficult.
authors.affiliation: Servicio de Traumatología y Cirugía Ortopédica, Hospital Clínico Universitario Lozano Blesa, Zaragoza, España.
authors.forename: J
authors.initials: J
authors.lastname: Segura
authors.forename: D
authors.initials: D
authors.lastname: Palanca
authors.forename: A L
authors.initials: AL
authors.lastname: Bueno
authors.forename: B
authors.initials: B
authors.lastname: Seral
authors.forename: T
authors.initials: T
authors.lastname: Castiella
authors.forename: F
authors.initials: F
authors.lastname: Seral
mesh_terms: D005260:Female; D015745:Granuloma, Foreign-Body / Q000139:chemically induced* / Q000000981:diagnostic imaging; D006801:Humans; D007720:Knee Prosthesis / Q000009:adverse effects*; D008875:Middle Aged; D011095:Polyethylenes / Q000009:adverse effects*; D011151:Popliteal Cyst / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D011475:Prosthesis Failure; D013997:Time Factors; D014057:Tomography, X-Ray Computed
chemical_list: D011095:Polyethylenes