title: Apoptosis as a proinflammatory event: what can we learn from bacteria-induced cell death?
abstract: Infection of cells by some pathogenic bacteria triggers host cell apoptosis. Bacteria-induced apoptosis appears to promote an inflammatory response that causes tissue damage and further bacterial colonization. Shigella pathogenesis offers a paradigm for the role of apoptosis in bacterial infections.
authors.affiliation: Dept of Microbiology, New York University School of Medicine, NY 10016, USA. zychlinsky@saturn.med.nyu.edu
authors.forename: A
authors.initials: A
authors.lastname: Zychlinsky
authors.forename: P J
authors.initials: PJ
authors.lastname: Sansonetti
mesh_terms: D017209:Apoptosis / Q000276:immunology*; D001424:Bacterial Infections / Q000276:immunology; D004405:Dysentery, Bacillary / Q000453:epidemiology / Q000276:immunology*; D006801:Humans; D007249:Inflammation / Q000503:physiopathology*; D008264:Macrophages