title: Mitochondrial DNA mutations in Japanese detected by polymerase chain reaction--restriction fragment--single strand conformation polymorphism analysis.
abstract: PCR-restriction fragment-SSCP (PCR-RF-SSCP) analysis of mitochondrial DNA by HhaI/HincII in Japanese revealed 46 polymorphic patterns. The determinations of nucleotide sequence of these 46 patterns revealed 56 mutations compared with the Cambridge Sequence.
authors.affiliation: Third Department of Internal Medicine, Yamanashi Medical University, Japan. tawatam@res.yamanashi-med.ac.jp
authors.forename: M
authors.initials: M
authors.lastname: Tawata
authors.forename: Y
authors.initials: Y
authors.lastname: Ikegishi
authors.forename: E
authors.initials: E
authors.lastname: Iwase
authors.forename: K
authors.initials: K
authors.lastname: Aida
authors.forename: T
authors.initials: T
authors.lastname: Onaya
mesh_terms: D004252:DNA Mutational Analysis / Q000379:methods*; D004272:DNA, Mitochondrial / Q000235:genetics*; D006801:Humans; D007564:Japan / Q000208:ethnology; D017354:Point Mutation; D016133:Polymerase Chain Reaction / Q000379:methods; D012150:Polymorphism, Restriction Fragment Length; D018807:Polymorphism, Single-Stranded Conformational
chemical_list: D004272:DNA, Mitochondrial