NMR structure of the 35-residue villin headpiece subdomain.
The NMR structure of an autonomously folding subdomain from villin headpiece is reported. It forms a novel three helix structure with the actin-binding residues arrayed on the C-terminal helix.
McKnight
C J
CJ
Matsudaira
P T
PT
Kim
P S
PS
D000595:Amino Acid Sequence; D002135:Calcium-Binding Proteins / Q000737:chemistry; D002352:Carrier Proteins / Q000737:chemistry*; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008840:Microfilament Proteins / Q000737:chemistry*; D008958:Models, Molecular; D008961:Models, Structural; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000737:chemistry*; D011487:Protein Conformation; D017433:Protein Structure, Secondary; D012984:Software
D002135:Calcium-Binding Proteins; D002352:Carrier Proteins; D008840:Microfilament Proteins; D010446:Peptide Fragments; C026615:villin