Non-infectious interstitial alveolitis and foreign body pulmonary vasculitis in a child treated for acute lymphoblastic leukemia.
We report a case of a 14-month-old girl who was treated for acute lymphoblastic leukemia but died from interstitial alveolitis associated with foreign body vasculitis. This respiratory complication arose 3 months after an allogenic bone marrow transplant. No infectious agents (bacteria, virus, or parasite) were isolated from bronchial or lung tissue samples. Respiratory complications after chemotherapy are reviewed as well as the potential origin of the intravascular foreign body.
Loriette
Y
Y
Department of Pediatrics, Hôtel Dieu University Hospital, Clermont-Ferrand, France.
Déchelotte
P
P
Carla
H
H
Dauphin
C
C
Demeocq
F
F
Labbé
A
A
D000970:Antineoplastic Agents / Q000009:adverse effects*; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D017809:Fatal Outcome; D005260:Female; D005549:Foreign-Body Reaction / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007223:Infant; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy*; D011658:Pulmonary Fibrosis / Q000175:diagnosis / Q000209:etiology*; D018366:Vasculitis, Leukocytoclastic, Cutaneous / Q000175:diagnosis / Q000209:etiology*
D000970:Antineoplastic Agents