Inherited factor X deficiency in two brothers.
Two brothers born to same parents were diagnosed with inherited factor X deficiency of severe type. Clinical presentation in both the cases were haemarthrosis. The elder brother was diagnosed in the year 1991 when he was four and half years old. Recently the youngest child in the family also presented with haemarthrosis at age of one and half years. Diagnosis was made by abnormal results of Coagulation factors screening mainly Prothrombin time, Activated partial thromboplastin time, Russell's viper venom test, mixing tests factor X assay. Both the brothers had Factor X activity less than one percent.
Barik
S
S
Department of Pathology and Haematology, Jawahar Lal Nehru Hospital and Research Centre, Bhilai-Durg, India.
Budhraja
A
A
Bhalla
M
M
Diwan
S
S
D002675:Child, Preschool; D005171:Factor X Deficiency / Q000175:diagnosis* / Q000235:genetics*; D006395:Hemarthrosis / Q000175:diagnosis; D006801:Humans; D007223:Infant; D008297:Male; D010375:Pedigree