title: Application of soluble dietary fibres in treatment of hyperlipoproteinemias.
abstract: Soluble dietary fibres as ingredients of our meal play an important role in both the prevention and treatment of hyperlipoproteinemias. We studied the effect of highly esterified sorbitol-granulated apple pectin on lipid metabolism in patients with hyperlipoproteinemia. They were all female (aged 40 to 60 years)-24 with type IIa and 23 with type IIb hyperlipoproteinemia. The levels of the total plasma cholesterol, the cholesterol in low- and high-density lipoproteins, plasma triglycerides, as well as the lipidogram in these patients were dynamically monitored for three months. Favourable changes of the basic parameters of lipid metabolism were the most essential being the changes in the plasma cholesterol in the first six weeks (P < 0.001). This parameter can adequately be used as a working criterion in controlling the therapeutic effect of pectin in hyperlipoproteinemias types IIa and IIb.
authors.affiliation: First Department of Internal Medicine, Higher Medical Institute, Plovdiv, Bulgaria.
authors.forename: J
authors.initials: J
authors.lastname: Grudeva-Popova
authors.forename: M
authors.initials: M
authors.lastname: Krachanova
authors.forename: A
authors.initials: A
authors.lastname: Djurdjev
authors.forename: C
authors.initials: C
authors.lastname: Krachanov
mesh_terms: D000328:Adult; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D004043:Dietary Fiber / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000097:blood / Q000178:diet therapy*; D008055:Lipids / Q000097:blood*; D008875:Middle Aged; D013997:Time Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D004043:Dietary Fiber; D008055:Lipids; D014280:Triglycerides; D002784:Cholesterol