title: Tumor suppressors: a developing role for p53?
abstract: An increasing body of evidence indicates that p53, the product of a tumour suppressor gene, has a role in development - could this developmental role have provided the primary driving force in the evolution of a protein best known as a stress-response integrator?
authors.affiliation: Department of Molecular and Cellular Pathology, University of Dundee, Dundee, DD1 9SY, UK.
authors.forename: P A
authors.initials: PA
authors.lastname: Hall
authors.forename: D P
authors.initials: DP
authors.lastname: Lane
mesh_terms: D000016:Abnormalities, Radiation-Induced / Q000235:genetics; D000222:Adaptation, Physiological / Q000235:genetics; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000818:Animals; D002648:Child; D002675:Child, Preschool; D005314:Embryonic and Fetal Development / Q000235:genetics*; D005313:Fetal Death / Q000209:etiology; D018507:Gene Expression Regulation, Developmental; D016158:Genes, p53; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D051379:Mice; D018345:Mice, Knockout; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology / Q000235:genetics*; D011833:Radiation Injuries, Experimental / Q000235:genetics; D013312:Stress, Physiological / Q000235:genetics / Q000503:physiopathology; D016159:Tumor Suppressor Protein p53 / Q000502:physiology*
chemical_list: D016159:Tumor Suppressor Protein p53