title: Moebius syndrome and central respiratory dysfunction.
abstract: Two infants, 18 months and 4 months of age, who were born with bilateral VI and VII nerve palsy (Moebius syndrome) experienced central respiratory failure requiring persistent ventilation. The computed tomography scan showed small brainstem tegmental calcifications. These findings suggest intrauterine brainstem necrosis including the respiratory center and poor prognosis for independent respiration.
authors.affiliation: Section of Neurology, University of Tennessee, Memphis, USA.
authors.forename: M
authors.initials: M
authors.lastname: Igarashi
authors.forename: D F
authors.initials: DF
authors.lastname: Rose
authors.forename: S A
authors.initials: SA
authors.lastname: Storgion
mesh_terms: D001927:Brain Diseases / Q000150:complications / Q000175:diagnosis; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis; D002114:Calcinosis / Q000150:complications / Q000175:diagnosis; D005158:Facial Paralysis / Q000150:complications*; D006801:Humans; D007223:Infant; D008067:Lipoma / Q000150:complications / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D012121:Respiration, Artificial; D012131:Respiratory Insufficiency / Q000150:complications* / Q000628:therapy; D014057:Tomography, X-Ray Computed