title: Is carcinoma breast a different disease in Pakistani population?
abstract: Carcinoma of the breast tends to be different in coloured and white races. Is this pattern also expressed in Pakistani population? To answer this query we carried out a retrospectively study of breast cancer on 193 cases who were divided into 2 groups i.e. less than and more than 50 years age groups. In the former group, 93% tumours were of grades II or III and approximately 51% were estrogen receptors negative. In more than 50 years age group, 75% tumors were in grade II and III, with almost 37% being estrogen negative tumors. Majority (75%) of the patients had over 6 cms lump with equal number having positive lymph node status. All these factors point to the fact that besides presenting late, our population has additional unfavourable prognostic factors.
authors.affiliation: Department of Pathology, Aga Khan University Medical Centre, Karachi.
authors.forename: R
authors.initials: R
authors.lastname: Ahmed
authors.forename: H
authors.initials: H
authors.lastname: Shaikh
authors.forename: S H
authors.initials: SH
authors.lastname: Hasan
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000737:chemistry / Q000235:genetics* / Q000473:pathology*; D002277:Carcinoma / Q000737:chemistry / Q000235:genetics* / Q000473:pathology*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009367:Neoplasm Staging; D010154:Pakistan; D011379:Prognosis; D011960:Receptors, Estrogen / Q000737:chemistry; D012189:Retrospective Studies
chemical_list: D011960:Receptors, Estrogen