Bilateral Candida parapsilosis endophthalmitis.
We describe a patient with bilateral, delayed endophthalmitis who underwent bilateral pars plana vitrectomy, total capsulectomy, intraocular lens exchange, intravitreal injection of amphotericin B, and oral fluconazole therapy. The long-term inflammation resolved, and vitreous cultures from both eyes yielded Candida parapsilosis. Histopathologic examination revealed sequestered yeast forms in the capsular bags.
Wong
V K
VK
Retina Service, Wills Eye Hospital, Philadelphia, Pa, USA.
Tasman
W
W
Eagle
R C
RC
Rodriguez
A
A
D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002175:Candida / Q000302:isolation & purification*; D002177:Candidiasis / Q000188:drug therapy / Q000209:etiology*; D009877:Endophthalmitis / Q000188:drug therapy / Q000382:microbiology*; D015821:Eye Infections, Fungal / Q000188:drug therapy / Q000209:etiology*; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D007267:Injections; D007903:Lens Capsule, Crystalline / Q000382:microbiology; D007910:Lenses, Intraocular; D008297:Male; D018918:Phacoemulsification / Q000009:adverse effects*; D014792:Visual Acuity; D014821:Vitrectomy
D000935:Antifungal Agents; D000666:Amphotericin B; D015725:Fluconazole