Hepatitis G virus/GB virus C in Brazil. Preliminary report.
Hepatitis G virus/GB virus C is a novel flavivirus recently detected in hepatitis non A-E cases. In this study, the presence of this virus in chronic non-B, non-C hepatitis patients was evaluated using GBV-C specific PCR and this virus was detected in one out of thirteen patients. This patient has presented a severe liver failure, has lived for a long time in the Western Amazon basin and no other cause for this clinical picture was reported. The impact of the discovery of this new agent is still under evaluation throughout the world. The study of the prevalence of this virus among chronic hepatitis patients and healthy individuals (as blood donors) will furnish subside to evaluate its real pathogenicity.
Pinho
J R
JR
Serviço de Virologia do Instituto Adolfo Lutz, São Paulo, Brasil.
Capacci
M L
ML
da Silva
L C
LC
Carrilho
F J
FJ
Santos
C A
CA
Pugliese
V
V
Guz
B
B
Levi
J E
JE
Ballarati
C A
CA
Bernardini
A P
AP
D000328:Adult; D000368:Aged; D001938:Brazil / Q000453:epidemiology; D002908:Chronic Disease; D005260:Female; D018067:Flaviviridae / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity; D006521:Hepatitis, Chronic / Q000453:epidemiology / Q000821:virology*; D006801:Humans; D008297:Male; D008875:Middle Aged