[The mechanism of histamine liberation from rat mast cells under the action of x-ray contrast media].
It was demonstrated in rat experiments that a positive direct correlation exists between the decrease in the amount of histamine in rat peritoneal must cells after intravenous infusion of radiopaque agents (ROA) in a dose of 2 ml/kg and the amount of these penetrating from the blood into the peritoneal cavity. The degree of penetration is determined by the chemical structure and/or physiochemical properties of the ROA.
Napolov
Iu K
IuK
D000818:Animals; D015550:Cell Degranulation / Q000187:drug effects*; D003287:Contrast Media / Q000494:pharmacology*; D003974:Diatrizoate Meglumine / Q000494:pharmacology*; D006636:Histamine Release / Q000187:drug effects*; D007451:Iodamide / Q000494:pharmacology*; D007457:Iodine Radioisotopes / Q000494:pharmacology*; D007458:Iodipamide / Q000494:pharmacology*; D008407:Mast Cells / Q000187:drug effects* / Q000502:physiology; D010529:Peritoneal Cavity / Q000166:cytology; D051381:Rats; D017208:Rats, Wistar; D018709:Statistics, Nonparametric
D003287:Contrast Media; D007457:Iodine Radioisotopes; D003974:Diatrizoate Meglumine; D007451:Iodamide; D007458:Iodipamide
Mekhanizm vysvobozhdeniia gistamina iz tuchnykh kletok krys pod deĭstviem rentgenokontrastnykh sredstv.