title: Antibiotic prophylaxis in ultrasound guided transrectal prostate biopsy.
abstract: OBJECTIVE
  A retrospective review of a large group of transrectal ultrasound guided biopsies was performed to determine the symptomatic urinary tract infection rate associated with a consistent and defined antibiotic prophylaxis regimen.
  
  
  METHODS
  A total of 4,439 biopsies was performed using an 18 gauge needle with ultrasound guidance. Patients were treated with 500 mg. ciprofloxacin twice daily for 8 doses beginning the day before biopsy.
  
  
  RESULTS
  Of 5 symptomatic urinary tract infections noted 3 were complicated.
  
  
  CONCLUSIONS
  These data demonstrate the low infection rate associated with this prophylaxis regimen.
authors.affiliation: Urological Associates of Lancaster, Ltd., Pennsylvania.
authors.forename: P R
authors.initials: PR
authors.lastname: Sieber
authors.forename: F M
authors.initials: FM
authors.lastname: Rommel
authors.forename: V E
authors.initials: VE
authors.lastname: Agusta
authors.forename: J A
authors.initials: JA
authors.lastname: Breslin
authors.forename: H W
authors.initials: HW
authors.lastname: Huffnagle
authors.forename: L E
authors.initials: LE
authors.lastname: Harpster
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D019072:Antibiotic Prophylaxis; D001707:Biopsy, Needle / Q000009:adverse effects* / Q000379:methods; D002939:Ciprofloxacin / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011467:Prostate / Q000000981:diagnostic imaging / Q000473:pathology*; D012189:Retrospective Studies; D014463:Ultrasonography; D014552:Urinary Tract Infections / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000890:Anti-Infective Agents; D002939:Ciprofloxacin