title: Intraocular pressure elevation after simple pars plana vitrectomy.
abstract: OBJECTIVE
  The purpose of the study is to determine the incidence, timing, and severity of variability in the intraocular pressures (IOPs) from baseline after simple pars plana vitrectomy.
  
  
  METHODS
  A prospective study was performed in 25 consecutive patients undergoing simple pars plana vitrectomy. Intraocular pressures were measured before surgery, immediately after surgery, and then at 2, 4, 6, 12, and 24 hours after surgery.
  
  
  RESULTS
  The mean IOP was elevated significantly 2 hours after surgery when compared with the mean immediate postoperative IOP (30.3 mmHg +/- 11.0 mmHg vs. 17.4 mmHg +/- 7.0 mmHg, P < 0.001). A steady decline was seen at all succeeding timepoints. The 24-hour mean (17.3 mmHg +/- 4.3 mmHg, P = 0.923) was similar to baseline. Ninety-two percent of eyes had a 2-hour postoperative IOP that was higher than the IOP at the completion of surgery. Forty percent of patients required medical management for IOP greater than or equal to 30 mmHg.
  
  
  CONCLUSIONS
  Significant IOP elevation can occur after simple pars plana vitrectomy. The optimal time for detecting the pressure rise during the first 24 hours is 2 hours after surgery.
authors.affiliation: Department of Ophthalmology, Henry Ford Health Sciences Center, Detroit, MI, USA.
authors.forename: U R
authors.initials: UR
authors.lastname: Desai
authors.forename: A A
authors.initials: AA
authors.lastname: Alhalel
authors.forename: R M
authors.initials: RM
authors.lastname: Schiffman
authors.forename: T J
authors.initials: TJ
authors.lastname: Campen
authors.forename: G
authors.initials: G
authors.lastname: Sundar
authors.forename: A
authors.initials: A
authors.lastname: Muhich
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005128:Eye Diseases / Q000601:surgery; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D011446:Prospective Studies; D014792:Visual Acuity; D014821:Vitrectomy / Q000009:adverse effects*