title: Fulminant septicemic syndrome of Bacillus cereus in a leukemic patient.
abstract: We report a rapidly fatal Bacillus cereus septicemia in a leukemic patient receiving remission-induction therapy. Symptoms resembling food poisoning and fever preceded coma accompanied by neurologic abnormalities. Autopsy revealed necrotizing leptomeningitis with subarachnoid hemorrhage and coagulation necrosis of the liver with bacterial infiltration. These clinicopathologic findings were closely similar to those of reported cases. Because of a rapidly fatal clinical course, suspicion of this syndrome early in the course is important to determine an appropriate treatment. Therefore, we propose that this type of septicemia should be termed as fulminant septicemic syndrome of Bacillus cereus.
authors.affiliation: Third Department of Internal Medicine, Faculty of Medicine, University of Tokyo.
authors.forename: N
authors.initials: N
authors.lastname: Akiyama
authors.forename: K
authors.initials: K
authors.lastname: Mitani
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Y
authors.initials: Y
authors.lastname: Hanazono
authors.forename: N
authors.initials: N
authors.lastname: Motoi
authors.forename: M
authors.initials: M
authors.lastname: Zarkovic
authors.forename: T
authors.initials: T
authors.lastname: Tange
authors.forename: H
authors.initials: H
authors.lastname: Hirai
authors.forename: Y
authors.initials: Y
authors.lastname: Yazaki
mesh_terms: D001409:Bacillus cereus; D016470:Bacteremia / Q000209:etiology*; D006801:Humans; D016867:Immunocompromised Host; D015470:Leukemia, Myeloid, Acute / Q000150:complications* / Q000473:pathology; D008099:Liver / Q000473:pathology; D008297:Male; D016920:Meningitis, Bacterial / Q000473:pathology; D008875:Middle Aged; D009336:Necrosis; D013345:Subarachnoid Hemorrhage / Q000473:pathology