Effects of components of meals (carbohydrate, fat, protein) in causing postprandial exertional angina pectoris.
We have shown that unlike fat, protein, xylose, or water, the carbohydrate component of the meal accelerates myocardial ischemia, reduces exercise capacity, and is associated with a more rapid increase in the determinants of myocardial oxygen consumption than exercise in the fasting state. Our results suggest a role for a larger increase in sympathetic nervous activity and/or release of vasoactive gastrointestinal peptides after carbohydrate, but not fat or protein, meals in postprandial angina.
Baliga
R R
RR
Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, United Kingdom.
Burden
L
L
Sidhu
M K
MK
Rampling
M W
MW
Kooner
J S
JS
D000787:Angina Pectoris / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D002395:Catecholamines / Q000097:blood; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D004041:Dietary Fats / Q000008:administration & dosage*; D004044:Dietary Proteins / Q000008:administration & dosage*; D004562:Electrocardiography; D004903:Erythrocyte Aggregation; D005080:Exercise Test; D006439:Hemodynamics; D006487:Hemostasis; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D005082:Physical Exertion; D019518:Postprandial Period; D014994:Xylose / Q000008:administration & dosage
D002395:Catecholamines; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D007328:Insulin; D014994:Xylose