title: Severe keratitis due to Nocardia farcinica.
abstract: Keratitis due to Nocardia farcinica occurred in a 49-year-old female after inappropriate cleaning of her semipermeable rigid contact lenses with basin-stored water during a holiday in France. N. farcinica was differentiated from Nocardia asteroides by its growth at 45 degrees C, acid production from rhamnose, its opacification of Middlebrook 7H10 agar, and its marked degree of resistance to all cephalosporins, aminoglycosides, tetracyclins, macrolides, and trimethoprim-sulfamethoxazole. To the best of our knowledge, this is the first reported case of human N. farcinica keratitis, confirming that this microorganism can be responsible for serious human disease.
authors.affiliation: Department of Ophthalmology, University Hospital Nijmegen, The Netherlands.
authors.forename: C A
authors.initials: CA
authors.lastname: Eggink
authors.forename: P
authors.initials: P
authors.lastname: Wesseling
authors.forename: P
authors.initials: P
authors.lastname: Boiron
authors.forename: J F
authors.initials: JF
authors.lastname: Meis
mesh_terms: D003261:Contact Lenses / Q000009:adverse effects; D005260:Female; D006801:Humans; D007634:Keratitis / Q000382:microbiology*; D008875:Middle Aged; D009615:Nocardia / Q000302:isolation & purification*; D009617:Nocardia Infections / Q000209:etiology / Q000382:microbiology* / Q000503:physiopathology