The use of cytokines in the treatment of solid tumours.
This manuscript reviews the clinical trials with cytokines in solid tumors. Starting with Interleukin 2 alone or in association with other cytokines and chemotherapy, the reviews opens the prospects of future direction for the use of cytokines as adjuvant therapy, for vaccination or to inhibit the growth activity of certain cytokines.
Fridman
W H
WH
Laboratoire d'Immunologie, Clinique et INSERM U 255, Institut Curie, Paris, France.
Tartour
E
E
D000818:Animals; D019496:Cancer Vaccines / Q000627:therapeutic use; D016207:Cytokines / Q000037:antagonists & inhibitors / Q000494:pharmacology / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D015316:Genetic Therapy; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*; D009374:Neoplasms, Experimental / Q000188:drug therapy
D019496:Cancer Vaccines; D016207:Cytokines