title: [Homology and evolution of gene orders: simulation and reconstruction of the evolutionary process].
abstract: A method to reconstruct the evolutionary history of observed gene orders from estimates of their similarity has been developed. It was shown that similarity measures accounting or not accounting for gene order in linkage groups of the compared genomes can be used for this purpose. A number of plausible variants of gene-order evolution from the common ancestral form in seven primate species were obtained.
authors.forename: I A
authors.initials: IA
authors.lastname: Zakharov
authors.forename: S V
authors.initials: SV
authors.lastname: Nikiforov
authors.forename: E V
authors.initials: EV
authors.lastname: Stepaniuk
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D003196:Computer Graphics; D003198:Computer Simulation; D019143:Evolution, Molecular; D006801:Humans; D008957:Models, Genetic; D011323:Primates / Q000235:genetics; D012689:Sequence Homology, Nucleic Acid
vernacular_title: Gomologiia i évoliutsiia gennykh poriadkov: modelirovanie i rekonstruktsiia évoliutsionnogo protsessa.