title: [Quinidine-induced rheumatic toxicity].
abstract: 2 women with quinidine-induced lupus are presented. This condition is rare; only about 30 cases have been reported in the English literature. Both our patients had arthritis of the wrist, antinuclear antibodies with homogenous pattern and elevated ESR. Anti-double stranded DNA antibodies were present in 1 patient, and a petechial rash in the other. Complete resolution of arthritis occurred within a few days after quinidine withdrawal, but antinuclear antibodies persisted for several months.
authors.affiliation: Dept. of Medicine C, Assaf Harofeh Medical Center, Zerifin.
authors.forename: D
authors.initials: D
authors.lastname: Almoznino-Sarafian
authors.forename: N
authors.initials: N
authors.lastname: Cohen
authors.forename: R
authors.initials: R
authors.lastname: Zaidenstein
authors.forename: V
authors.initials: V
authors.lastname: Dishi
authors.forename: E
authors.initials: E
authors.lastname: Zeckler
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001168:Arthritis / Q000139:chemically induced / Q000276:immunology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced*; D008875:Middle Aged; D011802:Quinidine / Q000009:adverse effects*; D014955:Wrist Joint
chemical_list: D011802:Quinidine