title: [Diastolic dysfunction of the left ventricle: from physiopathology to treatment].
abstract: Our understanding of cardiac failure has greatly changed over the last 15 years. Left ventricular diastolic dysfunction, which is now recognised as one of the primary causes of certain types of cardiac failure (1). Abnormal left ventricular diastolic function is the common determinant and indeed the earliest sign of all chronic left ventricular failures whether systolic left ventricular dysfunction is associated with it or not (2). In this paper, we review the basis of diastolic dysfunction and its impact on diagnosis and treatment of cardiac failure.
authors.affiliation: Division de Cardiologie, Centre Hospitalier Universitaire Vaudois, Lausanne.
authors.forename: H
authors.initials: H
authors.lastname: Karpuz
authors.forename: L
authors.initials: L
authors.lastname: Kappenberger
authors.forename: X
authors.initials: X
authors.lastname: Jeanrenaud
mesh_terms: D000368:Aged; D000375:Aging / Q000502:physiology; D002317:Cardiovascular Agents / Q000627:therapeutic use; D003971:Diastole / Q000502:physiology; D004359:Drug Therapy, Combination; D004562:Electrocardiography; D006801:Humans; D011379:Prognosis; D018487:Ventricular Dysfunction, Left / Q000188:drug therapy* / Q000503:physiopathology*
chemical_list: D002317:Cardiovascular Agents
vernacular_title: Dysfonction diastolique du ventricule gauche: de la physiopathologie au traitement.