title: Quantification of nucleic acids.
abstract: Quantification of nucleic acids is an area of growing importance in the clinical laboratory. In addition to routine measurements of total nucleic acid concentrations, quantitative techniques are used to determine the number of microorganisms in samples, the level of expression of genes, or the presence of alterations in gene dosage. This article provides an overview of current methodologies for measurement of total and specific nucleic acid concentrations.
authors.affiliation: Department of Pathology, University of Michigan, Ann Arbor, USA.
authors.forename: A A
authors.initials: AA
authors.lastname: Killeen
mesh_terms: D004247:DNA / Q000032:analysis*; D006801:Humans; D009693:Nucleic Acid Hybridization; D016133:Polymerase Chain Reaction; D012313:RNA / Q000032:analysis*; D013057:Spectrum Analysis / Q000379:methods
chemical_list: D012313:RNA; D004247:DNA