[Hypothermia during use of pipamperone].
Two women aged 84 and 86 years developed hypothermia after use of pipamperone. In one of the patients repeated administration of pipamperone again induced a decrease of body temperature. Although other clinical and environmental factors may have contributed to the development of hypothermia, a causal relationship between the use of pipamperone and the fall in body temperature appears likely considering the close temporal relationship. Hypothermia has been documented as a side effect of neuroleptics, especially phenothiazines, but it has not been reported in relation to pipamperone. Hypothermia is a potentially lethal condition; the cases described confirm the necessity of being careful with use of neuroleptics in elderly people.
Eikenboom
H C
HC
Rijnland Ziekenhuis, afd. Interne Geneeskunde, Leiderdorp.
Janssens
A R
AR
Rosekrans
P C
PC
Molendijk
W
W
D000368:Aged; D000369:Aged, 80 and over; D014150:Antipsychotic Agents / Q000009:adverse effects*; D002090:Butyrophenones / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007035:Hypothermia / Q000139:chemically induced* / Q000503:physiopathology
D014150:Antipsychotic Agents; D002090:Butyrophenones; C005569:pipamperone
Hypothermie bij gebruik van pipamperon.