title: A 51-year-old woman with nephrotic syndrome, hematuria, and renal insufficiency.
abstract: This case illustrates the utility of all modalities of the renal biopsy in arriving at a correct diagnosis in an adult patient with nephrotic syndrome. Unlike the clinical situation in children, where minimal change disease is presumed to underlie the nephrotic syndrome unless the patient shows steroid resistance, the list of differential diagnosis of nephrotic syndrome in the adult is lengthy. The renal biopsy is essential in establishing the specific diagnosis. We discuss the diagnostic approach in an adult patient with a relatively uncommon disease causing the common manifestations of nephrotic syndrome, hematuria and renal insufficiency.
authors.affiliation: Department of Pathology, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
authors.forename: A
authors.initials: A
authors.lastname: Fogo
authors.forename: R G
authors.initials: RG
authors.lastname: Horn
mesh_terms: D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006417:Hematuria / Q000473:pathology*; D006801:Humans; D007668:Kidney / Q000473:pathology; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000473:pathology*; D051437:Renal Insufficiency / Q000473:pathology*