title: Detection of Mycobacterium tuberculosis by molecular methods.
abstract: A review of the current literature regarding performance of the polymerase chain reaction and transcription mediated amplification with respect to diagnosis of tuberculosis is presented. Additional studies of the usefulness of these methods for predicting the efficacy of treatment by amplification of rRNA and DNA are also discussed. Application of the methodologies to nonrespiratory specimens for diagnosis of tuberculosis are presented.
authors.affiliation: Gen-Probe Incorporated, San Diego, California, USA.
authors.forename: V
authors.initials: V
authors.lastname: Jonas
authors.forename: M
authors.initials: M
authors.lastname: Longiaru
mesh_terms: D002851:Chromatography, High Pressure Liquid; D005784:Gene Amplification; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000235:genetics* / Q000302:isolation & purification*; D009693:Nucleic Acid Hybridization