title: Biopsy diagnosis and conservative surgical treatment of adenomyosis.
abstract: OBJECTIVE
  To diagnose adenomyosis by vaginal ultrasound and percutaneous or transcervical myometrial biopsy, and use the results to choose treatment and assess prognosis.
  
  
  METHODS
  Evaluation of 31 consecutive women referred by other physicians.
  
  
  METHODS
  A private gynecologic practice.
  
  
  METHODS
  The women had menstrual symptoms that had not responded to medical treatment or uterine curettage.
  
  
  METHODS
  Myometrial diagnosis was made by percutaneous ultrasound-guided needle biopsy, by transcervical electrosurgical loop biopsy at the time of endometrial resection, or by needle biopsy at the time of laparoscopy or laparotomy. Endometrial resection was performed in 15 patients, laparoscopic myometrial reduction in 7, and excision of adenomyotic myometrium or localized adenomyoma in 8.
  
  
  RESULTS
  Cure was defined as relief of menorrhagia and dysmenorrhea. Endometrial resection cured menorrhagia in 12 of 15 patients but dysmenorrhea in only 3 of 8; myometrial excision cured 7 of 8, and myometrial reduction 4 of 7 women.
  
  
  CONCLUSIONS
  Vaginal ultrasound combined with transabdominal or transcervical myometrial biopsy established the diagnosis of adenomyosis in all patients. Endometrial resection and myometrial reduction or excision reduced the need for hysterectomy to 30% in these women.
authors.affiliation: Department of Obstetrics and Gynaecology, Monash University, Melbourne, Australia.
authors.forename: C
authors.initials: C
authors.lastname: Wood
authors.forename: P
authors.initials: P
authors.lastname: Maher
authors.forename: D
authors.initials: D
authors.lastname: Hill
mesh_terms: D000328:Adult; D001707:Biopsy, Needle / Q000295:instrumentation / Q000379:methods; D004598:Electrosurgery; D004715:Endometriosis / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D010535:Laparoscopy; D007813:Laparotomy; D008599:Menstruation Disturbances / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D008875:Middle Aged; D011379:Prognosis; D014463:Ultrasonography; D014591:Uterine Diseases / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*