title: Giant hepatic angiomyolipoma associated with disseminated intravascular coagulation.
abstract: We report a case of giant hepatic angiomyolipoma in a 68-year-old woman who had an increase in the fibrinolytic activity concomitant with disseminated intravascular coagulation (DIC). The presence of the tumor was confirmed by ultrasound (US), computed tomography (CT) and magnetic resonance imaging (MRI) of the abdomen and the selective arteriography of the liver via the superior mesenteric artery. Following treatment with heparin and gabexate mesilate, abnormal hemostatic values were corrected. Furthermore, the surgical removal of the huge hepatic angiomyolipoma completely normalized the alternations of the clotting system. These findings suggest that giant hepatic angiomyolipoma was profoundly associated with DIC.
authors.affiliation: Department of Medicine, Holy Spirit Hospital, Nagoya.
authors.forename: K
authors.initials: K
authors.lastname: Ukai
authors.forename: A
authors.initials: A
authors.lastname: Fuji
authors.forename: J
authors.initials: J
authors.lastname: Nishiwaki
authors.forename: T
authors.initials: T
authors.lastname: Yamada
authors.forename: N
authors.initials: N
authors.lastname: Hotta
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: C
authors.initials: C
authors.lastname: Kondo
authors.forename: K
authors.initials: K
authors.lastname: Miyajima
authors.forename: T
authors.initials: T
authors.lastname: Takada
authors.forename: Y
authors.initials: Y
authors.lastname: Kinoshita
authors.forename: S
authors.initials: S
authors.lastname: Hanai
mesh_terms: D000368:Aged; D018207:Angiomyolipoma / Q000097:blood / Q000150:complications* / Q000601:surgery; D000925:Anticoagulants / Q000008:administration & dosage; D004211:Disseminated Intravascular Coagulation / Q000150:complications*; D005260:Female; D005342:Fibrinolysis; D016670:Gabexate / Q000008:administration & dosage; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D008113:Liver Neoplasms / Q000097:blood / Q000150:complications* / Q000601:surgery
chemical_list: D000925:Anticoagulants; D016670:Gabexate; D006493:Heparin