[The reaction of the cytoskeleton and smooth endoplasmic reticulum of Mauthner's neurons in goldfish to partial denervation and prolonged sensory stimulation].
Structure of smooth endoplasmic reticulum and cytoskeleton of goldfish Mauthner neurons were studied together with the behavior of fish after partial deafferentation of one of the dendrites with following long-term natural stimulation of another one and soma. Strong disturbance of cytoskeleton and proliferation of smooth endoplasmic reticulum especially of its transversely localised component accompanies exhaustion of Mauthner neurons caused by stimulation in normal absolute afferentation. On behavioral level it is manifests in significant suppression of fish motor activity. Similar stimulation of partly deafferentated Mauthner neurons turns to be more sparing both for fish behaviour and Mauthner neurons structure. Proliferation of endoplasmic reticulum was not in fact observed and in the cytoskeleton bundles of filaments were detected which implies improvement of its physico-chemical characteristics and increase of resistance to external factors. Probably, this relative resistance of partly deafferentated Mauthner neurons of fish to long-term natural stimulation is conditioned predominantly by postsynaptic mechanisms and is likely linked with reorganization in cytoskeleton, caused by preliminary change of Mauthner neurons innervation.
Santalova
I M
IM
Moshkov
D A
DA
D000818:Animals; D003599:Cytoskeleton / Q000648:ultrastructure*; D003714:Denervation; D018871:Endoplasmic Reticulum, Smooth / Q000648:ultrastructure*; D006054:Goldfish / Q000033:anatomy & histology* / Q000502:physiology; D008854:Microscopy, Electron; D009043:Motor Activity; D009474:Neurons / Q000648:ultrastructure*; D010812:Physical Stimulation; D012399:Rotation; D013550:Swimming
Reaktsiia tsitoskeleta i gladkoĭ éndoplazmaticheskoĭ seti mautnerovskikh neĭronov zolotykh rybok na chastichnuiu denervatsiiu i dlitel'nuiu sensornuiu stimuliatsiiu.