title: Nucleolar organizer regions (AgNORs) in intraepithelial neoplasia of the uterine cervix.
abstract: The authors have studied the AgNORs counts in intraepithelial lesions of the uterine cervix. The following values were obtained (mean +/- SD AgNORs/cell): normal specimens--2.11 +/- 0.98; mild dysplasia--2.83 +/- 1.12; moderate dysplasia--3.42 +/- 1.13; severe dysplasia--3.55 +/- 1.28; carcinoma in situ--4.63 +/- 1.34; glandular extensions of carcinoma in situ--4.64 +/- 0.98. The values in moderate and severe dysplasia were similar, an argument for grouping these categories in the high-grade lesions. AgNORs counts in carcinoma in situ were, however, higher than in severe dysplasia, suggesting a continuous evolution of the neoplastic process.
authors.affiliation: Department of Morphopathology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca.
authors.forename: D
authors.initials: D
authors.lastname: Crişan
authors.forename: C D
authors.initials: CD
authors.lastname: Olinici
authors.forename: A
authors.initials: A
authors.lastname: Răşinariu
authors.forename: A M
authors.initials: AM
authors.lastname: Basaraba
mesh_terms: D005260:Female; D006801:Humans; D009697:Nucleolus Organizer Region / Q000648:ultrastructure*; D016622:Silver Staining; D002578:Uterine Cervical Dysplasia / Q000648:ultrastructure*