Is carcinoma breast a different disease in Pakistani population?
Carcinoma of the breast tends to be different in coloured and white races. Is this pattern also expressed in Pakistani population? To answer this query we carried out a retrospectively study of breast cancer on 193 cases who were divided into 2 groups i.e. less than and more than 50 years age groups. In the former group, 93% tumours were of grades II or III and approximately 51% were estrogen receptors negative. In more than 50 years age group, 75% tumors were in grade II and III, with almost 37% being estrogen negative tumors. Majority (75%) of the patients had over 6 cms lump with equal number having positive lymph node status. All these factors point to the fact that besides presenting late, our population has additional unfavourable prognostic factors.
Ahmed
R
R
Department of Pathology, Aga Khan University Medical Centre, Karachi.
Shaikh
H
H
Hasan
S H
SH
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000737:chemistry / Q000235:genetics* / Q000473:pathology*; D002277:Carcinoma / Q000737:chemistry / Q000235:genetics* / Q000473:pathology*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009367:Neoplasm Staging; D010154:Pakistan; D011379:Prognosis; D011960:Receptors, Estrogen / Q000737:chemistry; D012189:Retrospective Studies
D011960:Receptors, Estrogen