Type III secretion systems: machines to deliver bacterial proteins into eukaryotic cells?
Type III secretion systems in certain bacterial pathogens are induced upon contact with host cells and directly deliver virulence proteins into the host cell cytosol. The increasing number of Gram-negative bacterial pathogens discovered to encode type III secretion systems raises interesting questions. Are type III systems generic machines that deliver virulence proteins into host cells? Is contact with host cells a common regulatory cue for type III systems?
Lee
C A
CA
Dept of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA. clee@warren.med.harvard.edu
D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D005057:Eukaryotic Cells; D015964:Gene Expression Regulation, Bacterial
D001426:Bacterial Proteins