title: [The effect of long-term uncontrolled antihypertensive therapy on the echocardiographic signs of left-heart hypertrophy in patients with mild and moderate arterial hypertension].
abstract: The data are presented on the absence of a stable positive trend in echocardiographic characteristics of the left heart and intracardiac hemodynamics after 8 months of controlled antihypertensive therapy, 12-month follow-up and uncontrolled outpatient treatment. 12 months after discontinuation of controlled antihypertensive therapy arterial pressure was much higher than it was at the end of the treatment in patients taking antihypertensive drugs irregularly or not taking them at all. Intracardiac hemodynamics returned to the baseline. As shown by echo-CG, frequency of left ventricular hypertrophy 12 months after the end of antihypertensive treatment rose from 25.8 to 45.2% (p < 0.01), of right ventricular hypertrophy from 14.5 to 17.7%.
authors.forename: O V
authors.initials: OV
authors.lastname: Lerman
authors.forename: V I
authors.initials: VI
authors.lastname: Metelitsa
authors.forename: N P
authors.initials: NP
authors.lastname: Filatova
authors.forename: S G
authors.initials: SG
authors.lastname: Duda
authors.forename: N V
authors.initials: NV
authors.lastname: Malysheva
authors.forename: V A
authors.initials: VA
authors.lastname: Vygodin
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D016009:Chi-Square Distribution; D002908:Chronic Disease; D004452:Echocardiography / Q000187:drug effects* / Q000706:statistics & numerical data; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D013997:Time Factors
chemical_list: D000959:Antihypertensive Agents
vernacular_title: Vliianie dlitel'noĭ nekontroliruemoĭ antigipertenzivnoĭ terapii na ékhokardiograficheskie priznaki gipertrofii levykh otdelov serdtsa u bol'nykh miagkoĭ i umerennoĭ arterial'noĭ gipertonieĭ.