Minocycline-related lupus erythematosus with associated liver disease.
A young woman developed minocycline-related lupus erythematosus with associated autoimmune hepatitis. All clinical and laboratory abnormalities returned to normal when the drug was stopped. The symptoms worsened dramatically upon rechallenge, strongly suggesting the reaction was related to the minocycline.
Crosson
J
J
Department of Pathology, Hennepin County Medical Center, Minneapolis, MN 55415, USA.
Stillman
M T
MT
D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D001327:Autoimmune Diseases / Q000139:chemically induced*; D005260:Female; D006505:Hepatitis / Q000209:etiology* / Q000276:immunology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced*; D008911:Minocycline / Q000009:adverse effects*
D000900:Anti-Bacterial Agents; D008911:Minocycline