Carbamazepine-induced sinus node dysfunction.
Carbamazepine, a drug used for the treatment of epilepsy and neuralgias, may exert hazardous effects on the cardiac conduction system. We report such a case of symptomatic brady-arrhythmia occurring in a 43-years-old male while on therapy with carbamazepine. Additionally, a literature review is made of previous cases of carbamazepine-induced sinus mode, AV node and His-Purkinje conduction disturbances.
Johnson
C D
CD
Department of Medicine, University of Puerto Rico, San Juan 00936-5067, USA.
Rivera
H
H
Jiménez
J E
JE
D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects* / Q000097:blood; D002220:Carbamazepine / Q000009:adverse effects* / Q000097:blood; D015716:Electrocardiography, Ambulatory / Q000187:drug effects; D004827:Epilepsy / Q000150:complications / Q000188:drug therapy; D006801:Humans; D008297:Male; D012804:Sick Sinus Syndrome / Q000139:chemically induced / Q000175:diagnosis / Q000503:physiopathology; D012849:Sinoatrial Node / Q000187:drug effects* / Q000503:physiopathology
D000927:Anticonvulsants; D002220:Carbamazepine