title: [Visceral granulomas and pericardial effusion caused by a Bartonella henselae infection].
abstract: A 57 year-old woman was seen after a three-week period of upper abdominal pain, nausea, fever, headache and exertional dyspnoea. Laboratory examination showed an elevated ESR and serum gamma-GT activity. The chest X-ray showed cardiomegaly resulting from a pericardial effusion as was demonstrated by echocardiography. An abdominal CT-scan disclosed multiple hypodense lesions in the liver and spleen and lymphadenopathy along the hepatoduodenal ligament. Liver biopsy showed a necrotising granulomatous hepatitis. A recent infection with Bartonella, presumably B. henselae, was demonstrated serologically. The patient was treated with clarithromycin and recovered.
authors.affiliation: Afd. Interne Geneeskunde, Slotervaartziekenhuis, Amsterdam.
authors.forename: R C
authors.initials: RC
authors.lastname: Bakker
authors.forename: H
authors.initials: H
authors.lastname: van Heukelem
authors.forename: M M
authors.initials: MM
authors.lastname: van de Sandt
authors.forename: A M
authors.initials: AM
authors.lastname: Bergmans
mesh_terms: D000907:Antibodies, Bacterial / Q000302:isolation & purification; D018416:Bartonella henselae / Q000276:immunology; D001706:Biopsy; D004066:Digestive System Diseases / Q000382:microbiology*; D005260:Female; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D006099:Granuloma / Q000382:microbiology*; D006505:Hepatitis / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology; D008875:Middle Aged; D013158:Splenic Diseases / Q000382:microbiology; D014057:Tomography, X-Ray Computed
chemical_list: D000907:Antibodies, Bacterial
vernacular_title: Viscerale granulomen en pericardeffusie veroorzaakt door een infectie met Bartonella henselae.