title: Mapping structural damage of the optic disk to visual field defect in glaucoma.
abstract: OBJECTIVE
  To evaluate the relation between the location of focal visual field defects and optic disk damage in eyes with glaucoma by short-wavelength automated perimetery and confocal scanning laser ophthalmoscopy.
  
  
  METHODS
  In 14 patients (14 eyes) with open-angle glaucoma, focal optic disk damage, and focal visual field loss, we obtain visual fields with short-wave-length automated perimetry. The short-wavelength automated perimetry visual field was divided into 21 zones, representing retinal nerve fiber layer arcuate bundles. Test points were compared with a normative database. The optic disk was assessed with a confocal scanning laser ophthalmoscope. Optic disk measurements were calculated in 10-degree sectors and compared with a normative database using a new measure, the rim area ratio, which adjusts for individual differences in disk size.
  
  
  RESULTS
  The mean number (+/-SD) of damaged visual field zones was 3.9 (+/-1.9), and the mean number of damaged rim sectors was 5.0 (+/-2.9). Focal defects on the optic disk and on short-wavelength automated perimetry were topographically related with specific damaged visual field zones corresponding to specific damaged rim sectors.
  
  
  CONCLUSIONS
  In patients with open-angle glaucoma with focal optic disk damage and focal visual field loss, defects in optic disk and short-wavelength automated perimetry are topographically related. The rim area ratio can be used to identify focal optic nerve defects.
authors.affiliation: Department of Ophthalmology, University of California, San Diego, La Jolla 92093-0946, USA.
authors.forename: N
authors.initials: N
authors.lastname: Yamagishi
authors.forename: A
authors.initials: A
authors.lastname: Anton
authors.forename: P A
authors.initials: PA
authors.lastname: Sample
authors.forename: L
authors.initials: L
authors.lastname: Zangwill
authors.forename: A
authors.initials: A
authors.lastname: Lopez
authors.forename: R N
authors.initials: RN
authors.lastname: Weinreb
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005902:Glaucoma, Open-Angle / Q000473:pathology*; D006801:Humans; D007834:Lasers; D008875:Middle Aged; D009412:Nerve Fibers / Q000473:pathology; D009885:Ophthalmology / Q000295:instrumentation; D009898:Optic Disk / Q000473:pathology*; D014786:Vision Disorders / Q000473:pathology*; D058609:Visual Field Tests / Q000379:methods; D014794:Visual Fields