[Respiratory dyskinesia induced by veralipride].
We describe the case of a patient whose menopause syndrome was treated with veralipride. After four months of this treatment she started to have bucco-lingual movements and marked dyspnea which caused difficult, irregular breathing and severe thoracic discomfort. After the drug was stopped there was progressive improvement and disappearance of the symptoms described. When the patient was taking a neuroleptic drug (veralipride) she developed bucco-lingual dyskinesia, considered to be the commonest late dyskinesia, together with marked respiratory dyskinesia. The latter is a type of dyskinesia seldom described, probably because it is only detected when it is severe enough to cause functional effects. It may pass unnoticed when the disorder is only slight or moderate. In the literature there are few references to disorders of movement induced by this drug, especially when compared with other benzamides which are frequently involved. However, in its mode of action there is a beneficial antigonadotropin activity together with an antidopaminergic effect which explains why they may cause such a reaction.
Marta-Moreno
E
E
Servicio de Neurologia, Hospital Miguel Servet, Zaragoza, España.
Gracia-Naya
M
M
Marzo-Sola
M E
ME
D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004409:Dyskinesia, Drug-Induced / Q000150:complications* / Q000209:etiology*; D005260:Female; D006801:Humans; D008593:Menopause; D008875:Middle Aged; D012120:Respiration Disorders / Q000150:complications*; D013469:Sulpiride / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use
D014150:Antipsychotic Agents; D013469:Sulpiride; C027429:veralipride
Discinesia respiratoria inducida por veralipride.