Cell motility: complex dynamics at the leading edge.
The intracellular pathogen Listeria monocytogenes is a useful model for general actin-based cell motility, because it recruits host actin and associated proteins for movement. Recent data have shown that these associated proteins include the Ena/VASP family of proteins and the actin-related proteins Arp2 and Arp3.
Machesky
L M
LM
Department of Molecular Medicine, University College London, Gower Street, London WC1E 6BT, UK.
D000048:Acanthamoeba / Q000737:chemistry / Q000648:ultrastructure; D051377:Actin-Related Protein 2; D000199:Actins / Q000502:physiology; D000818:Animals; D015815:Cell Adhesion Molecules / Q000502:physiology; D002465:Cell Movement; D003598:Cytoskeletal Proteins; D004268:DNA-Binding Proteins / Q000502:physiology; D005656:Fungal Proteins / Q000502:physiology; D008089:Listeria monocytogenes / Q000502:physiology; D046911:Macromolecular Substances; D008840:Microfilament Proteins; D010750:Phosphoproteins / Q000502:physiology; D015800:Protozoan Proteins / Q000502:physiology; D015003:Yeasts / Q000502:physiology; D000098662:Vasodilator-Stimulated Phosphoprotein
D051377:Actin-Related Protein 2; D000199:Actins; D015815:Cell Adhesion Molecules; D003598:Cytoskeletal Proteins; D004268:DNA-Binding Proteins; C092744:ENA-VASP proteins; D005656:Fungal Proteins; D046911:Macromolecular Substances; D008840:Microfilament Proteins; D010750:Phosphoproteins; D015800:Protozoan Proteins; D000098662:Vasodilator-Stimulated Phosphoprotein