Mild rhabdomyolysis after high-dose trimethoprim-sulfamethoxazole in a patient with HIV infection.
Adverse drug reactions to trimethoprim-sulfamethoxazole (TMP/SMX) are common in HIV-positive patients. However, only one case of TMP/SMX-related rhabdomyolysis has been reported, so far. We report a 55-year old-man with asymptomatic rhabdomyolysis after oral high-dose TMP/SMX for suspected PCP. Laboratory changes settled after discontinuation of the drug.
Anders
H J
HJ
Medizinische Poliklinik, Ludwig-Maximilians University, Munich, D-80336, Germany.
Bogner
J R
JR
Goebel
F D
FD
D017088:AIDS-Related Opportunistic Infections / Q000150:complications / Q000188:drug therapy*; D000890:Anti-Infective Agents / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D011020:Pneumonia, Pneumocystis / Q000150:complications / Q000188:drug therapy*; D012206:Rhabdomyolysis / Q000139:chemically induced* / Q000150:complications; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000009:adverse effects* / Q000627:therapeutic use
D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination