title: Mossy leg with eccrine syringofibroadenomatous hyperplasia resembling multiple eccrine syringofibroadenoma.
abstract: Eccrine syringofibroadenoma (ES) is a histological entity with a polymorphous clinical presentation. We describe a patient who had multiple nodules on both of his legs resembling lymphoedematous keratoderma (mossy leg or elephantiasis) in the absence of any vascular or lymphatic incompetence. The histological features were those of ES. A surgical resection was effective. Our case is probably an eccrine sweat duct reactive hyperplasia rather than a neoplasia or hamartoma.
authors.affiliation: Department of Dermatology, University of Genoa, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Rongioletti
authors.forename: C
authors.initials: C
authors.lastname: Gambini
authors.forename: A
authors.initials: A
authors.lastname: Parodi
authors.forename: G
authors.initials: G
authors.lastname: Cannata
authors.forename: A
authors.initials: A
authors.lastname: Rebora
mesh_terms: D006607:Adenoma, Sweat Gland / Q000473:pathology*; D003937:Diagnosis, Differential; D004604:Elephantiasis / Q000473:pathology*; D018226:Fibroadenoma / Q000473:pathology*; D006801:Humans; D006965:Hyperplasia; D007866:Leg; D008297:Male; D008875:Middle Aged; D013545:Sweat Glands / Q000473:pathology*