Synthesis and antibacterial activities of some 4,5-dihydro-1H-1,2,4-triazol-5-ones.
Twenty-one new 1-methyl- and 1-ethyl-3,4-disubstituted-4,5-dihydro- 1H-1,2,4-triazol-5-ones were synthesized and characterised by elemental analysis, 1H-NMR and IR spectra. These new and 16 recently reported derivatives of 4,5-dihydro-1H-1,2,4-triazol-5-one ring were screened for their antibacterial activities.
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Department of Chemistry, Karadeniz Technical University, Trabzon, Turkey.
Demirbaş
A
A
Ikizler
A
A
Johansson
C B
CB
Celik
C
C
Ikizler
A A
AA
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000995:Antitubercular Agents / Q000138:chemical synthesis / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D013056:Spectrophotometry, Ultraviolet; D014230:Triazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000995:Antitubercular Agents; D014230:Triazoles