title: Drosophila development. Delimiting patterns by repression.
abstract: Patterning of the Drosophila embryo requires not only the proper activation of determinants at specific times, but also their restriction to specific places. Recent studies on transcriptional repressors show how they delimit the gene expression patterns to ensure normal development.
authors.affiliation: Program in Molecular Medicine, University of Massachusetts Medical Center, Worcester, Massachusetts, 01605 USA. Tony.lp@ummed.edu
authors.forename: Y T
authors.initials: YT
authors.lastname: Ip
authors.forename: K
authors.initials: K
authors.lastname: Hemavathy
mesh_terms: D000818:Animals; D004330:Drosophila / Q000196:embryology* / Q000235:genetics; D029721:Drosophila Proteins; D004625:Embryo, Nonmammalian / Q000502:physiology*; D004627:Embryonic Induction; D018507:Gene Expression Regulation, Developmental; D017344:Genes, Insect; D009687:Nuclear Proteins / Q000096:biosynthesis; D010750:Phosphoproteins / Q000096:biosynthesis; D012097:Repressor Proteins / Q000096:biosynthesis*; D014157:Transcription Factors
chemical_list: D029721:Drosophila Proteins; D009687:Nuclear Proteins; D010750:Phosphoproteins; D012097:Repressor Proteins; D014157:Transcription Factors; C062236:dl protein, Drosophila