Genetic relationships of Asians and Northern Europeans, revealed by Y-chromosomal DNA analysis.
We have identified a new T-->C transition on the human Y chromosome. C-allele chromosomes have been found only in a subset of the populations from Asia and northern Europe and reach their highest frequencies in Yakut, Buryats, and Finns. Examination of the microsatellite haplotypes of the C-allele chromosomes suggests that the mutation occurred recently in Asia. The Y chromosome thus provides both information about population relationships in Asia and evidence for a substantial paternal genetic contribution of Asians to northern European populations such as the Finns.
Zerjal
T
T
Department of Biochemistry, University of Oxford, United Kingdom.
Dashnyam
B
B
Pandya
A
A
Kayser
M
M
Roewer
L
L
Santos
F R
FR
Schiefenhövel
W
W
Fretwell
N
N
Jobling
M A
MA
Harihara
S
S
Shimizu
K
K
Semjidmaa
D
D
Sajantila
A
A
Salo
P
P
Crawford
M H
MH
Ginter
E K
EK
Evgrafov
O V
OV
Tyler-Smith
C
C
D000818:Animals; D001208:Asia; D044466:Asian People / Q000235:genetics*; D001483:Base Sequence; D005075:Biological Evolution; D005060:Europe; D005787:Gene Frequency; D005819:Genetic Markers; D005843:Geography; D006239:Haplotypes; D015186:Hominidae / Q000235:genetics*; D006801:Humans; D007802:Language; D008297:Male; D018895:Microsatellite Repeats; D008969:Molecular Sequence Data; D017354:Point Mutation; D044465:White People / Q000235:genetics*; D014998:Y Chromosome / Q000235:genetics*
D005819:Genetic Markers