Validity of the 13-C-urea breath test for the diagnosis of Helicobacter pylori infection.
Infection with Helicobacter pylori (H. pylori) plays an important role in the pathogenesis of gastritis, peptic ulcer and gastric cancer, and the 13C-urea breath test (13C-UBT) is a convenient and non-invasive method for the detection of H. pylori in the stomach. We have examined the sensitivity, specificity and accuracy of 13C-UBT. The 13CO2/12CO2 ratio was measured using infrared spectroscopy (IR) and gas chromatography/mass spectrometry (GC-MS).
Kajiwara
M
M
Dept. of Medicinal Chemistry, Meiji College of Pharmacy, Tokyo, Japan.
Iida
K
K
Takatori
K
K
Taniguchi
Y
Y
Kimura
K
K
D001944:Breath Tests / Q000379:methods; D008401:Gas Chromatography-Mass Spectrometry; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori; D006801:Humans; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013055:Spectrophotometry, Infrared