title: [Ultrasound and clinical studies of periventricular leukomalacia in high risk newborn infants. I. Neuro-ultrasound results].
abstract: The incidence of periventricular leukomalacia (PVL) in risk neonates was evaluated in a prospective ultrasound study at the Pediatric Hospital of the Medical Faculty, University of Rostock. The study was carried out in 300 registered risk neonates. These risk neonates were divided into 3 groups: < or = 31 gestational week (n = 70), 32-36 gestational week (n = 154), > or = 37 gestational week (n = 76). A prenatal PVL was diagnosed in 41 neonates, a postnatal PVL was found in 56 neonates after the 5th day of life. In 77% of all risk neonates with PVL, the diagnosis was made on the first day of life. After the first day of life, PVL was presented mainly in highly immature neonates. A correlation of PVL to gestational age could only be found in neonates with postnatal PVL. Subarachnoid space enlargement was found to be significantly more frequent in risk neonates with prenatal PVL than in risk infants with postnatal PVL. Residual ultrasound findings of PVL were significantly more frequent in male than in female risk neonates.
authors.affiliation: Universitäts-Kinder- und Iugendklinik, Universität Rostock.
authors.forename: K N
authors.initials: KN
authors.lastname: Staneva
authors.forename: G
authors.initials: G
authors.lastname: Bartolomaeus
authors.forename: C
authors.initials: C
authors.lastname: Plath
authors.forename: M
authors.initials: M
authors.lastname: Müller
authors.forename: M
authors.initials: M
authors.lastname: Uhlemann
authors.forename: R
authors.initials: R
authors.lastname: Terpe
mesh_terms: D001925:Brain Damage, Chronic / Q000000981:diagnostic imaging; D002552:Cerebral Ventricles / Q000000981:diagnostic imaging; D004453:Echoencephalography; D005260:Female; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000000981:diagnostic imaging*; D007969:Leukomalacia, Periventricular / Q000000981:diagnostic imaging*; D008297:Male; D009460:Neurologic Examination; D011247:Pregnancy; D011446:Prospective Studies; D012307:Risk Factors; D016216:Ultrasonography, Prenatal
vernacular_title: Sonographische und klinische Untersuchungen zur periventrikulären Leukomalazie bei Risikoneugeborenen. I. Neurosonographische Untersuchungsergebnisse.