Inhibition of thymidylate synthase: biochemical pharmacology of drugs with activity in colorectal cancer.
Jackman
A L
AL
CRC Centre for Cancer Therapeutics, Institute of Cancer Research, Sutton, Surrey, UK.
D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology* / Q000627:therapeutic use; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000201:enzymology*; D004791:Enzyme Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D005472:Fluorouracil / Q000494:pharmacology; D006801:Humans; D008727:Methotrexate / Q000494:pharmacology; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors*
D000964:Antimetabolites, Antineoplastic; D004791:Enzyme Inhibitors; D013940:Thymidylate Synthase; D005472:Fluorouracil; D008727:Methotrexate