title: Quantitative assessment of callus distraction using dual energy X-ray absorptiometry.
abstract: Bone mineralisation during and after limb lengthening procedures on the femur or tibia using unilateral fixators has been monitored quantitatively using dual energy X-ray absorptiometry (DEXA). We measured the bone mineral density (BMD) prospectively in the newly formed callus, in the bone adjacent to the callus and in the proximal femur. In twenty-one patients we showed a typical course with a peak value at 4-6 weeks after beginning distraction and a minimum value at maximum distraction. In the consolidation period the BMD in the distraction gap increased until the fixator was removed. The BMD in the regenerated bone increased faster in the regions of interest (ROI) opposite the fixator compared to those near it. Dynamisation caused more homogeneous regeneration equalising VBMD in the different ROIs. The BMD in the proximal femur of the leg which was operated on decreased to 67% and in the opposite leg to 87% of the preoperative value. DEXA provides a precise and quantitative assessment of callus and bone mineralisation during limb lengthening and helps in understanding what is happening during these procedures.
authors.affiliation: University Orthopaedic Clinic, Heidelberg, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Reiter
authors.forename: D
authors.initials: D
authors.lastname: Sabo
authors.forename: J
authors.initials: J
authors.lastname: Pfeil
authors.forename: H
authors.initials: H
authors.lastname: Cotta
mesh_terms: D015502:Absorptiometry, Photon; D000293:Adolescent; D000328:Adult; D015519:Bone Density; D001852:Bone Lengthening; D002146:Bony Callus / Q000502:physiology*; D002113:Calcification, Physiologic / Q000502:physiology*; D016267:External Fixators; D005260:Female; D005269:Femur / Q000601:surgery; D006801:Humans; D008297:Male; D011446:Prospective Studies; D018709:Statistics, Nonparametric