title: [Lipid peroxidation and antioxidant defense in renal affections of exotoxic etiology].
abstract: Exogenic poisoning is often complicated by toxic nephropathy pathogenesis of which remains obscure. In view of this, the authors have performed a clinical study of lipid peroxidation (LPO) and antioxidant defense (AOD) in acute exogenic poisoning with renal lesion. Acute poisoning results in LPO activation and inhibition of AOD enzymes activity. Emerging toxic nephropathy aggravates disorders in the system LPO-AOD actively participating in pathogenesis of this complication.
authors.affiliation: State Medical Institute, Karaganda.
authors.forename: T Z
authors.initials: TZ
authors.lastname: Seisembekov
authors.forename: B K
authors.initials: BK
authors.lastname: Aitpaev
authors.forename: L E
authors.initials: LE
authors.lastname: Muravleva
authors.forename: E A
authors.initials: EA
authors.lastname: Alimbaev
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000975:Antioxidants / Q000378:metabolism*; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000139:chemically induced / Q000378:metabolism*; D015227:Lipid Peroxidation / Q000187:drug effects / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D010084:Oxidation-Reduction; D011042:Poisons / Q000009:adverse effects*
chemical_list: D000975:Antioxidants; D011042:Poisons
vernacular_title: Pereokisnoe okislenie lipidov i sistema antioksidatnoi zashchity pri porazheniiakh pochek ekzotoksicheskoi etiologii.