Allergic contact dermatitis from pyoctanin.
Although pyoctanin is widely used in medicine, there are hardly any reports of contact allergy to it. Most reports of side-effects refer to irritant reactions after topical application. We describe 2 patients who developed pyoctanin contact dermatitis after long-term application on damaged skin. Positive patch test results down to concentrations of 0.0025% and 0.05% aqueous pyoctanin solution, respectively, were found.
Schoppelrey
H P
HP
Department of Dermatology and Allergology, City Hospital München-Schwabing, Germany.
Mily
H
H
Agathos
M
M
Breit
R
R
D000287:Administration, Topical; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D005533:Foot Dermatoses / Q000175:diagnosis / Q000188:drug therapy; D005840:Gentian Violet / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007868:Leg Dermatoses / Q000175:diagnosis / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D017444:Skin Diseases, Papulosquamous / Q000175:diagnosis / Q000188:drug therapy; D014008:Tinea Pedis / Q000175:diagnosis / Q000188:drug therapy
D000305:Adrenal Cortex Hormones; D000891:Anti-Infective Agents, Local; D005840:Gentian Violet