title: Crohn's disease and gastrocnemius vasculitis: two new cases.
abstract: We report two cases of gastrocnemius muscle vasculitis revealing Crohn's disease. Gastrocnemius muscle biopsy evidenced a necrotizing vasculitis resembling panarteritis nodosa in one case; a nonnecrotizing vasculitis was found in the other case. Neither of the patients had systemic vasculitic involvement, and the muscle disease resembled calf muscle-located panarteritis nodosa. Our literature review shows five cases of calf-located myalgia occurring during Crohn's disease characterized by heterogenous histopathological findings including vasculitic and myositic lesions. Thus, faced with calf-located myalgia with vasculitis or myositis, a search for Crohn's disease is probably necessary to determine precisely the frequency and the etiopathogenic mechanisms of this association.
authors.affiliation: Service de Médecine Interne, Hôpital de la Timone, Marseille, France.
authors.forename: P
authors.initials: P
authors.lastname: Disdier
authors.forename: L
authors.initials: L
authors.lastname: Swiader
authors.forename: J R
authors.initials: JR
authors.lastname: Harlé
authors.forename: J F
authors.initials: JF
authors.lastname: Pellissier
authors.forename: D
authors.initials: D
authors.lastname: Figarella-Branger
authors.forename: V
authors.initials: V
authors.lastname: Veit
authors.forename: A
authors.initials: A
authors.lastname: Gérolami
authors.forename: P h
authors.initials: Ph
authors.lastname: Arlet
authors.forename: P J
authors.initials: PJ
authors.lastname: Weiller
mesh_terms: D000328:Adult; D001706:Biopsy; D003424:Crohn Disease / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D018482:Muscle, Skeletal / Q000098:blood supply* / Q000473:pathology; D014657:Vasculitis / Q000209:etiology* / Q000473:pathology