title: A case of secondary pulmonary hypertension due to microscopic pulmonary tumor cell embolism from gallbladder carcinoma.
abstract: We describe a case of subacute cor pulmonale caused by tumor embolism from a gallbladder carcinoma in a 63-year-old woman. The patient was admitted to hospital with increasing dyspnea. Physical examination and echocardiography showed signs of pulmonary hypertension. She died of circulatory failure. At autopsy microscopic studies revealed tumor embolism in the pulmonary vessels and subsequent lesions causing the lethal pulmonary hypertension. This is the first case report of pulmonary hypertension caused by embolism from a gallbladder carcinoma in the literature worldwide.
authors.affiliation: Departments of Pneumology, Ramón y Cajal Hospital, University of Alcalá de Henares, Spain.
authors.forename: D A
authors.initials: DA
authors.lastname: de Luis
authors.forename: J
authors.initials: J
authors.lastname: Darriba
authors.forename: P
authors.initials: P
authors.lastname: San Miguel
authors.forename: S G
authors.initials: SG
authors.lastname: Rull
authors.forename: C
authors.initials: C
authors.lastname: Cuesta
authors.forename: I
authors.initials: I
authors.lastname: Fogue
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000556:secondary*; D017809:Fatal Outcome; D005260:Female; D005706:Gallbladder Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000209:etiology*; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011651:Pulmonary Artery; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000209:etiology*; D014463:Ultrasonography; D019043:Vascular Neoplasms / Q000175:diagnosis / Q000556:secondary*