title: [Large granular T-cell lymphocytic leukemia disclosed by bilateral uveitis: association with celiac disease].
abstract: A 70-year-old woman presented with bilateral anterior uveitis. She was on a gluten-free diet because of a celiac disease which had been diagnosed 3 months before. An anterior chamber aspirate contained a majority of large granular lymphocytes (LGL). The investigation of a chronic neutropenia led to the diagnosis of an otherwise typical T-LGL leukemia. This seems to be the first report of a CD3+ CD4- CD8+ T-LGL leukemia causing anterior uveitis through infiltration of leukemic cells, and the second report of an intriguing association of celiac disease with T-LGL leukemia.
authors.affiliation: Service d'hématologie, Hôtel-Dieu de Montréal, Québec, Canada.
authors.forename: J L
authors.initials: JL
authors.lastname: Molitor
authors.forename: J
authors.initials: J
authors.lastname: Saint-Louis
authors.forename: C
authors.initials: C
authors.lastname: Louvet
authors.forename: A
authors.initials: A
authors.lastname: Vachon
authors.forename: L
authors.initials: L
authors.lastname: Vincent
authors.forename: R
authors.initials: R
authors.lastname: Beaulieu
mesh_terms: D000368:Aged; D002446:Celiac Disease / Q000150:complications*; D005260:Female; D006801:Humans; D015461:Leukemia, Prolymphocytic, T-Cell / Q000150:complications* / Q000503:physiopathology; D009503:Neutropenia / Q000209:etiology / Q000503:physiopathology; D014606:Uveitis, Anterior / Q000209:etiology*
vernacular_title: Leucémie à grands lymphocytes granuleux T révélée par une uvéite bilatérale: association à une maladie coeliaque.