title: Effects of components of meals (carbohydrate, fat, protein) in causing postprandial exertional angina pectoris.
abstract: We have shown that unlike fat, protein, xylose, or water, the carbohydrate component of the meal accelerates myocardial ischemia, reduces exercise capacity, and is associated with a more rapid increase in the determinants of myocardial oxygen consumption than exercise in the fasting state. Our results suggest a role for a larger increase in sympathetic nervous activity and/or release of vasoactive gastrointestinal peptides after carbohydrate, but not fat or protein, meals in postprandial angina.
authors.affiliation: Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, United Kingdom.
authors.forename: R R
authors.initials: RR
authors.lastname: Baliga
authors.forename: L
authors.initials: L
authors.lastname: Burden
authors.forename: M K
authors.initials: MK
authors.lastname: Sidhu
authors.forename: M W
authors.initials: MW
authors.lastname: Rampling
authors.forename: J S
authors.initials: JS
authors.lastname: Kooner
mesh_terms: D000787:Angina Pectoris / Q000097:blood / Q000209:etiology* / Q000503:physiopathology; D002395:Catecholamines / Q000097:blood; D004040:Dietary Carbohydrates / Q000008:administration & dosage*; D004041:Dietary Fats / Q000008:administration & dosage*; D004044:Dietary Proteins / Q000008:administration & dosage*; D004562:Electrocardiography; D004903:Erythrocyte Aggregation; D005080:Exercise Test; D006439:Hemodynamics; D006487:Hemostasis; D006801:Humans; D007328:Insulin / Q000097:blood; D008297:Male; D005082:Physical Exertion; D019518:Postprandial Period; D014994:Xylose / Q000008:administration & dosage
chemical_list: D002395:Catecholamines; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004044:Dietary Proteins; D007328:Insulin; D014994:Xylose