[Role of the rpoS gene in the regulation of expression of plasmid genes determining the synthesis of C51 microcin].
In cells mutant for the rpoS gene coding the sigma s subunit of RNA polymerase, synthesis of antibiotic microcin C51, which is produced by Escherichia coli, is absent or extremely reduced. In experiments with a cloned promoter of the microcin operon, the sigma s subunit was shown to participate in regulation of transcription of plasmid genes that determine microcin synthesis.
Fomenko
D E
DE
Dziumenko
E V
EV
Khmel'
I A
IA
D000900:Anti-Bacterial Agents / Q000096:biosynthesis*; D001430:Bacteriocins / Q000096:biosynthesis / Q000235:genetics*; D003001:Cloning, Molecular; D004926:Escherichia coli / Q000235:genetics*; D015964:Gene Expression Regulation, Bacterial / Q000502:physiology*; D005798:Genes, Bacterial; D005815:Genetic Code; D009154:Mutation; D009876:Operon; D010957:Plasmids / Q000235:genetics*
D000900:Anti-Bacterial Agents; D001430:Bacteriocins; C020411:microcin
Uchastie gena rpoS v reguliatsii ékspressii plazmidnykh genov, opredeliaiushchikh sintez mikrotsina C51.