title: Models of exocrine pancreatic pathologies: a microscopical point of view.
abstract: The objective of this review is to emphasize the contribution of optical and electronic microscopy to the study of the normal and pathological rat pancreas. These basic techniques used to explore the pancreatic morphology are capital to precisely localize specific enzymes or proteins in cellular subcompartments, to establish the normal or the pathological state of the gland, and to detect and describe unusual structures that appear under certain experimental conditions.
authors.affiliation: Département de Biologie, Université de Sherbrooke, Québec, Canada.
authors.forename: G
authors.initials: G
authors.lastname: Grondin
authors.forename: J
authors.initials: J
authors.lastname: Morisset
authors.forename: A R
authors.initials: AR
authors.lastname: Beaudoin
authors.forename: D
authors.initials: D
authors.lastname: Lebel
mesh_terms: D000305:Adrenal Cortex Hormones / Q000494:pharmacology; D000818:Animals; D002471:Cell Transformation, Neoplastic; D003550:Cystic Fibrosis / Q000473:pathology; D010179:Pancreas / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D051381:Rats
chemical_list: D000305:Adrenal Cortex Hormones