["CHARGE" association].
CHARGE association represents a group of congenital anomalies with no clear etiology. The broad array of abnormalities, which involves several systems, has been the basis for the acronym CHARGE: coloboma, heart anomaly, choanal atresia, retarded growth and development, hypoplastic genitalia and ear malformation. We present 3 children with CHARGE association to illustrate the phenotypic variability and note the multidisciplinary treatment they received. It is recommended that this entity be approached in an interdisciplinary, integrated way to allow for faster diagnosis and better prognosis.
Barak
A
A
Pediatric Dept., Kaplan Hospital, Rehovot.
Gabis
L
L
Mogilner
B
B
Gelman-Kohan
S
S
D000015:Abnormalities, Multiple / Q000235:genetics* / Q000628:therapy; D002754:Choanal Atresia / Q000235:genetics; D003103:Coloboma / Q000235:genetics; D002658:Developmental Disabilities / Q000235:genetics; D004423:Ear / Q000002:abnormalities; D005835:Genitalia / Q000002:abnormalities; D006330:Heart Defects, Congenital / Q000235:genetics; D006801:Humans; D007223:Infant; D010641:Phenotype