Nucleotide sequence, chromosome localization, and evolutionary conservation of a serine hydroxymethyltransferase-processed pseudogene.
The nucleotide sequence and chromosomal localization of a human pseudogene is reported. Sequence data suggest that this pseudogene was derived via reverse transcription from the gene encoding the cytosolic isoform of the enzyme serine hydroxymethyltransferase. In addition, a heteroduplex analysis of this pseudogene among several species of nonhuman primate indicates a relatively high degree of sequence conservation.
Devor
E J
EJ
Department of Psychiatry, University of Iowa College of Medicine, Iowa City 52242-1000, USA.
Dill-Devor
R M
RM
D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D017124:Conserved Sequence / Q000235:genetics*; D003600:Cytosol; D012696:Glycine Hydroxymethyltransferase / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D011323:Primates; D011544:Pseudogenes / Q000235:genetics*; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid
D012696:Glycine Hydroxymethyltransferase