title: Ivemark syndrome with asplenia in siblings.
abstract: We describe two siblings with Ivemark syndrome. In both cases, absent spleen, symmetric liver, and lungs with three lobes were associated with complex cardiac malformation. The syndrome was diagnosed prenatally in the second case by fetal echocardiography at the twentieth week of pregnancy. The autosomal recessive mode of inheritance of Ivemark syndrome is further supported by these cases.
authors.affiliation: First Department of Obstetrics and Gynecology, Semmelweis University, Budapest, Hungary.
authors.forename: I
authors.initials: I
authors.lastname: Cesko
authors.forename: J
authors.initials: J
authors.lastname: Hajdú
authors.forename: T
authors.initials: T
authors.lastname: Tóth
authors.forename: T
authors.initials: T
authors.lastname: Marton
authors.forename: C
authors.initials: C
authors.lastname: Papp
authors.forename: Z
authors.initials: Z
authors.lastname: Papp
mesh_terms: D000015:Abnormalities, Multiple / Q000000981:diagnostic imaging / Q000235:genetics*; D005260:Female; D005318:Fetal Heart / Q000000981:diagnostic imaging; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D008099:Liver / Q000002:abnormalities; D008297:Male; D009679:Nuclear Family; D011247:Pregnancy; D013154:Spleen / Q000002:abnormalities*; D013577:Syndrome; D016216:Ultrasonography, Prenatal