Microvascular anatomy of striate vessels in dogs: contribution to an experimental model of forebrain ischemia.
Basal perforating vessels such as Heubner's artery are involved in various arteriopathic conditions resulting in cognitive and memory deficits. In order to evaluate if a model of focal forebrain ischemia can be obtained in dogs, a systematic study of the microvascular anatomy of the striate vessels was performed using intravascular injections of acrylic paint and/or India ink. Medial and lateral striate arteries were identified and found distinct either by their superficial anatomy as well as their deep perfusion territories. One medial striate artery emerging consistently from the junction of the A1 segment of the anterior cerebral artery and the ethmoidal artery resembles the human recurrent artery of Heubner. Therefore, the dog may provide a suitable model of forebrain ischemia involving solely the perfusion territory of the medial striate arteries.
St-Jacques
R
R
Sir Mortimer B. Davis - Jewish General Hospital, McGill University, Montreal, Canada.
Gorczyca
W
W
Mohr
G
G
D000716:Anatomy, Artistic; D000818:Animals; D001158:Arteries / Q000033:anatomy & histology*; D002545:Brain Ischemia / Q000473:pathology; D004195:Disease Models, Animal; D004285:Dogs; D005260:Female; D008297:Male; D008488:Medical Illustration; D008833:Microcirculation; D010781:Photography; D016548:Prosencephalon / Q000098:blood supply; D014793:Visual Cortex / Q000098:blood supply*