Adie syndrome as the initial sign of primary Sjögren syndrome.
OBJECTIVE
To report Adie syndrome as the initial sign of primary Sjögren syndrome.


METHODS
Case report.


RESULTS
Adie syndrome was associated with necrotizing gingivitis and xerostomia. Antibodies against Ro (SS-A) were present. Prednisone and antimalarial drugs were ineffective in treating Adie syndrome but improved the necrotizing gingivitis.


CONCLUSIONS
Search for Sjögren syndrome is mandated in patients with Adie syndrome. The latter condition is likely related to ganglionitis, a mechanism responsible for peripheral nervous system involvement in primary Sjögren syndrome.
Bachmeyer
C
C
Service de Médecine Interne, Hôpital Cochin, Creil, France.
Zuber
M
M
Dupont
S
S
Blanche
P
P
Dhôte
R
R
Mas
J L
JL
D000270:Adie Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000974:Antibodies, Antinuclear / Q000032:analysis; D000962:Antimalarials / Q000627:therapeutic use; D001324:Autoantigens / Q000276:immunology; D005260:Female; D005892:Gingivitis, Necrotizing Ulcerative / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D011241:Prednisone / Q000627:therapeutic use; D020733:RNA, Small Cytoplasmic; D012261:Ribonucleoproteins / Q000276:immunology; D012859:Sjogren's Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D014987:Xerostomia / Q000175:diagnosis / Q000188:drug therapy; D000099207:SS-A Antigen
D000893:Anti-Inflammatory Agents; D000974:Antibodies, Antinuclear; D000962:Antimalarials; D001324:Autoantigens; D011241:Prednisone; D020733:RNA, Small Cytoplasmic; D012261:Ribonucleoproteins; D000099207:SS-A Antigen; C116006:RO60 protein, human; C035356:SS-A antibodies