title: Laser photocoagulation around the foci of toxoplasma retinochoroiditis: a descriptive statistical analysis of 35 patients with long-term follow-up.
abstract: Thirty-five patients with toxoplasma retinochoroiditis, receiving medical treatment and then treated with laser photocoagulation around the foci, were retrospectively evaluated for the risk of recurrence of the retinochoroiditis with a Kaplan-Meier representation. The recurrence rates with 95% symmetric confidence intervals were: at 1 year, 12.7 + or - 13%, at 2 years, 19.8 + or - 15%; at 3 years, 24.0 + or - 16%; at 4 years, 33.3 + or - 19%; at 5,6 and 7 years, 53.5 + or - 21%; at 8 and 9 years 66. 8 + or - 22%. With the data provided by our series, it is not possible to show the efficacy of laser photocoagulation as a prevention of recurrence in toxoplasma retinochoroiditis. Moreover, because of their heterogeneity, the recurrence rates from the literature cannot provide precise data for a comparison. Concerning the laser-induced thermal damage, the potential therapeutic mechanism of the laser procedure is discussed.
authors.affiliation: Service d'Ophtalmologie, Hopital Huriez, CHRU, Lille, France.
authors.forename: T
authors.initials: T
authors.lastname: Desmettre
authors.forename: P
authors.initials: P
authors.lastname: Labalette
authors.forename: B
authors.initials: B
authors.lastname: Fortier
authors.forename: S
authors.initials: S
authors.lastname: Mordon
authors.forename: G
authors.initials: G
authors.lastname: Constantinides
mesh_terms: D000293:Adolescent; D000328:Adult; D002825:Chorioretinitis / Q000469:parasitology / Q000473:pathology / Q000601:surgery*; D002829:Choroid / Q000469:parasitology / Q000473:pathology / Q000601:surgery; D003627:Data Interpretation, Statistical; D005500:Follow-Up Studies; D006801:Humans; D017075:Laser Coagulation / Q000379:methods*; D011183:Postoperative Complications; D012008:Recurrence; D012160:Retina / Q000469:parasitology / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies; D014126:Toxoplasmosis, Ocular / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome