title: [A nidulans bronchial aspergillosis after treatment of low-grade lymphoma with fludarabine].
abstract: Pulmonary aspergillosis is a common complication in neutropenic patients. The most important fungus is Aspergillus fumigatus. We report a case of invasive pulmonary aspergillosis due to Aspergillus nidulans secondary to fludarabine therapy. There are few cases of pulmonary aspergillosis due to Aspergillus nidulans (one chronic necrotizing pulmonary aspergillosis, one aspergilloma). Fludarabine induces a marked decreased of CD4 lymphocyte count responsible for opportunistic infections. It is the first case of aspergillosis after fludarabine therapy and the occurrence of such infection must be considered after purine analog therapy.
authors.affiliation: Service d'hématologie-médecine interne, hôpital de Cimiez, Nice, France.
authors.forename: F
authors.initials: F
authors.lastname: Peyrade
authors.forename: A
authors.initials: A
authors.lastname: Boscagli
authors.forename: M
authors.initials: M
authors.lastname: Roa
authors.forename: B
authors.initials: B
authors.lastname: Taillan
authors.forename: M
authors.initials: M
authors.lastname: Gary-Toussain
authors.forename: P
authors.initials: P
authors.lastname: Dujardin
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects*; D001228:Aspergillosis / Q000209:etiology* / Q000382:microbiology; D001982:Bronchial Diseases / Q000209:etiology* / Q000382:microbiology; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy*; D008297:Male; D014740:Vidarabine / Q000009:adverse effects / Q000031:analogs & derivatives*
chemical_list: D000970:Antineoplastic Agents; D014740:Vidarabine; C024352:fludarabine
vernacular_title: Aspergillose bronchique à A nidulans après traitement par fludarabine d'un lymphome de bas grade.