Do neuroleptic drugs hasten cognitive decline in dementia? Carriers of apolipoprotein E epsilon 4 allele seem particularly susceptible to their effects.
Holmes
C
C
Fortenza
O
O
Powell
J
J
Lovestone
S
S
D000483:Alleles; D014150:Antipsychotic Agents / Q000009:adverse effects*; D053327:Apolipoprotein E4; D001057:Apolipoproteins E / Q000235:genetics*; D003072:Cognition Disorders / Q000139:chemically induced*; D003704:Dementia / Q000188:drug therapy*; D005500:Follow-Up Studies; D006801:Humans
D014150:Antipsychotic Agents; D053327:Apolipoprotein E4; D001057:Apolipoproteins E