[Study of the protective effects of phenothiazine derivatives on a stochastic model of brain compression edema-swelling].
Search for pathogenically substantiated drugs to treat and prevent brain edema-swelling (BES) is a topical problem of modern biology and medicine. It is possible to solve this challenging biomedical problem by using a method for devising a stochastic model of the tested process. The developed stochastic model of BES identifies the nerve tissue structural components involving in the anti-edematous mechanism of action of phenothiazine derivatives under the conditions of 7-day brain compression. Analyzing the results of this model application revealed the major governing structures in the morphofunctional complexes under study. The investigations made on the stochastic model yielded a quantitative assessment of the impact of morphofunctional structural relationships under the influence of disturbing factors.
Platonov
I A
IA
D000818:Animals; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D001929:Brain Edema / Q000517:prevention & control*; D009408:Nerve Compression Syndromes / Q000517:prevention & control*; D018696:Neuroprotective Agents / Q000627:therapeutic use*; D010640:Phenothiazines; D051381:Rats; D013269:Stochastic Processes
D014150:Antipsychotic Agents; D018696:Neuroprotective Agents; D010640:Phenothiazines
Issledovanie na stokhasticheskoĭ modeli kompressionnogo oteka-nabukhaniia golovnogo mozga protektivnogo deĭstviia proizvodnykh fenotiazina.