Florida's undeclared epidemic: malignant melanoma.
Contrary to the trend of early diagnosis observed in other parts of the world, in Florida melanoma is still being discovered in the more advanced stages. This is characterized by thicker lesions at diagnosis, which are hallmarked by bleeding, itching, ulceration, and increased vertical growth. In a study of 1,626 cutaneous melanoma patients at the H. Lee Moffitt Cancer Center in Florida, three prognostic factors, tumor thickness, Clark level, and presence of ulceration in the primary tumor, have remained relatively constant over an eight-year period (1987-1994). Despite the lack of change in tumor thickness in the last four years, mortality rate is decreasing, possibly due to more effective treatments. Regardless of these apparent improvements in mortality rates, definite progress must be made in the early detection of malignant melanoma through the initiation of statewide programs of lay public and professional education. In addition, it is proposed that the establishment of statewide screening programs of the Caucasian population with skin phenotypes 1 and 2 will also facilitate the early diagnosis of melanoma in the future, improve the outlook for these patients, and begin to address a major public health problem in the state of Florida.
Kamath
D
D
Cutaneous Oncology Program Moffitt Cancer Center, USF, Tampa, USA.
Cantor
A B
AB
Glass
F
F
Fenske
N
N
Cruse
C W
CW
Wells
K
K
Rapaport
D
D
DeConti
R
R
Messina
J
J
Reintgen
D
D
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004196:Disease Outbreaks; D004501:Education, Medical; D005260:Female; D005431:Florida / Q000453:epidemiology; D006266:Health Education; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods; D008545:Melanoma / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology / Q000517:prevention & control; D008875:Middle Aged; D009367:Neoplasm Staging; D010641:Phenotype; D011379:Prognosis; D011634:Public Health; D012878:Skin Neoplasms / Q000453:epidemiology* / Q000401:mortality / Q000473:pathology / Q000517:prevention & control; D012880:Skin Pigmentation / Q000235:genetics; D012883:Skin Ulcer / Q000473:pathology; D044465:White People