[Environmental factors and iatrogenic elements in systemic scleroderma and related syndromes. Review of the literature].
The etiology of scleroderma remains unknown. Although a genetic susceptibility seems to play a role, some environmental and iatrogenic factors have been suggested to trigger the disease. Contact for many months or years with natural or synthetic "toxic" products (by inhalation, cutaneous contact, injection, swallowing or surgical implant) could be implicated in the development of typical scleroderma or pseudo-scleroderma. These products are either occupational or non occupational like those used at home in daily life. We will sum up the knowledges about this subject.
Hallé
O
O
Service de rhumatologie, hôpital Pellegrin-Tondu, CHU de Bordeaux, France.
Schaeverbeke
T
T
Bannwarth
B
B
Dehais
J
J
D004781:Environmental Exposure; D006801:Humans; D007049:Iatrogenic Disease; D016273:Occupational Exposure; D012595:Scleroderma, Systemic / Q000139:chemically induced / Q000209:etiology* / Q000503:physiopathology
Les facteurs d'environnement et les éléments iatrogènes dans la sclérodermie systémique et les syndromes apparentés. Revue de la littérature.