[Large granular T-cell lymphocytic leukemia disclosed by bilateral uveitis: association with celiac disease].
A 70-year-old woman presented with bilateral anterior uveitis. She was on a gluten-free diet because of a celiac disease which had been diagnosed 3 months before. An anterior chamber aspirate contained a majority of large granular lymphocytes (LGL). The investigation of a chronic neutropenia led to the diagnosis of an otherwise typical T-LGL leukemia. This seems to be the first report of a CD3+ CD4- CD8+ T-LGL leukemia causing anterior uveitis through infiltration of leukemic cells, and the second report of an intriguing association of celiac disease with T-LGL leukemia.
Molitor
J L
JL
Service d'hématologie, Hôtel-Dieu de Montréal, Québec, Canada.
Saint-Louis
J
J
Louvet
C
C
Vachon
A
A
Vincent
L
L
Beaulieu
R
R
D000368:Aged; D002446:Celiac Disease / Q000150:complications*; D005260:Female; D006801:Humans; D015461:Leukemia, Prolymphocytic, T-Cell / Q000150:complications* / Q000503:physiopathology; D009503:Neutropenia / Q000209:etiology / Q000503:physiopathology; D014606:Uveitis, Anterior / Q000209:etiology*
Leucémie à grands lymphocytes granuleux T révélée par une uvéite bilatérale: association à une maladie coeliaque.