title: Case report. Two contrasting radiological presentations of prostatic adenocarcinoma in the jaws.
abstract: The contrasting radiological appearances of metastatic deposits in the mandible of prostatic adenocarcinoma in two patients are described. The clinical presentation was similar in that both presented with altered sensation of the lower lip. Radiologically, they differed in that one patient suffered from a large predominantly osteoblastic mass, while the other, who gave a history of previously treated prostatic adenocarcinoma, presented with a rather small osteolytic deposit. Investigations for bony metastatic disease usually include a bone scan which is a highly sensitive technique although non-specific. A skeletal survey can be useful although less sensitive than a bone scan. Blood investigations such as acid phosphatase and prostate specific antigen levels are also indicated in male patients where prostatic disease is suspected. Reasonable long term survival using relatively simple drug therapy without significant local surgery, highlights the need for accurate recognition and tissue diagnosis to differentiate this condition from osseous malignancy of the jaws, other metastatic disease or osteomyelitis.
authors.affiliation: Department of Dental and Maxillofacial Radiology, Leeds Dental Institute, UK.
authors.forename: F A
authors.initials: FA
authors.lastname: Carmichael
authors.forename: D A
authors.initials: DA
authors.lastname: Mitchell
authors.forename: D P
authors.initials: DP
authors.lastname: Dyson
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000556:secondary* / Q000628:therapy; D006801:Humans; D008297:Male; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary* / Q000628:therapy; D011471:Prostatic Neoplasms / Q000473:pathology*; D011862:Radiography, Panoramic