title: The convergence of murein recycling research with beta-lactamase research.
abstract: The story of how investigation of Escherichia coli cell wall elongation evolved into a study of murein recycling and how this led to the discovery that ampG and ampD were required for both murein recycling and beta-lactamase regulation is chronicled. Preliminary information on two other genes believed to be involved in recycling, nagZ, the structural gene for beta-N-acetylglucosaminidase, and tpl, the presumed structural gene for the hypothetical tripeptide-adding enzyme, is presented. The possibility that recycling of murein fragments serves a signaling function is discussed.
authors.affiliation: Department of Molecular Biology and Microbiology, Tufts University, Boston, Massachusetts 02111, USA.
authors.forename: J T
authors.initials: JT
authors.lastname: Park
mesh_terms: D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics / Q000378:metabolism*; D010457:Peptidoglycan / Q000096:biosynthesis / Q000235:genetics / Q000378:metabolism*; D001618:beta-Lactamases / Q000096:biosynthesis / Q000235:genetics / Q000378:metabolism*
chemical_list: D010457:Peptidoglycan; D001618:beta-Lactamases