Regulation of the fatty acid synthase gene by retinoic acid in HepG2 cells is mediated by an E-box-containing multihormonal response element and two neighbouring upstream sequences.
Roder
K H
KH
Genetics & Microbiology Department, Institute of Food Research, Colney, Norwich, UK.
Wolf
S S
SS
Schweizer
M
M
D000818:Animals; D006528:Carcinoma, Hepatocellular; D002460:Cell Line; D064429:Fatty Acid Synthases / Q000096:biosynthesis* / Q000235:genetics*; D015971:Gene Expression Regulation, Enzymologic / Q000187:drug effects*; D015972:Gene Expression Regulation, Neoplastic; D017930:Genes, Reporter; D006801:Humans; D008113:Liver Neoplasms; D008156:Luciferases / Q000096:biosynthesis; D016297:Mutagenesis, Site-Directed; D011401:Promoter Regions, Genetic; D051381:Rats; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis; D012045:Regulatory Sequences, Nucleic Acid; D017384:Sequence Deletion; D014158:Transcription, Genetic; D014212:Tretinoin / Q000494:pharmacology*
D011993:Recombinant Fusion Proteins; D014212:Tretinoin; D008156:Luciferases; D064429:Fatty Acid Synthases