title: Progression of human bone ingrowth into porous-coated implants. Rate of bone ingrowth in humans.
abstract: We report the measured progression of human cancellous bone ingrowth into load-bearing porous-coated titanium implants over 5 time periods (0, 3, 6, 9, and 12 months). There was a statistically significant progression of bone ingrowth into the implants over a 9-month period, but the 9- and 12-month data were not different. Investigators are advised to analyze time "0" implants in order to distinguish mechanical impaction of bone from the biological process of bone ingrowth.
authors.affiliation: Department of Orthopaedics, University of Utah School of Medicine, Salt Lake City 84132, USA.
authors.forename: A A
authors.initials: AA
authors.lastname: Hofmann
authors.forename: R D
authors.initials: RD
authors.lastname: Bloebaum
authors.forename: K N
authors.initials: KN
authors.lastname: Bachus
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001858:Bone Nails; D005260:Female; D005269:Femur; D006801:Humans; D007592:Joint Diseases / Q000601:surgery; D007719:Knee Joint; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D016348:Osseointegration / Q000502:physiology*; D016062:Porosity; D013997:Time Factors; D014025:Titanium; D016474:Weight-Bearing
chemical_list: D014025:Titanium