Central nervous system ischemia after varicella infection and desmopressin therapy for enuresis.
A 7-year-old boy had a left-sided cerebrovascular accident 48 hours after beginning intranasal desmopressin acetate (DDAVP) therapy for persistent secondary nocturnal enuresis and approximately 2 weeks after varicella infection. A possible connection between desmopressin therapy or varicella infection (or both) and the patients neurologic symptoms is discussed, as is the relationship of desmopressin with hypercoagulability, Suggestions for patient/parent education, medical history taking, and patient surveillance are offered to prescribing physicians.
Wieting
J M
JM
Department of Physical Medicine and Rehabilitation, Michigan State University, College of Osteopathic Medicine, East Lansing 48824, USA.
Dykstra
D D
DD
Ruggiero
M P
MP
Robbins
G B
GB
Galusha
K
K
D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging / Q000209:etiology*; D002644:Chickenpox / Q000150:complications*; D002648:Child; D003894:Deamino Arginine Vasopressin / Q000009:adverse effects*; D004775:Enuresis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D012076:Renal Agents / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
D012076:Renal Agents; D003894:Deamino Arginine Vasopressin