title: Antibiotic susceptibility of group A streptococci in a national consultant hospital in Dar es Salaam: a four year follow-up.
abstract: Seventy one Group A streptococcal strains isolated between 1992 and 1995 at Muhimbili Medical Centre in Dar es Salaam were found to be susceptible to penicillin G and cotrimoxazole. All except two strains, which showed intermediate susceptibility, were susceptible to erythromycin. Sixty five strains (91.5%) were resistant to doxycycline. The findings confirm continuing efficacy of penicillin G, erythromycin and contrimoxazole in treating Group A streptococci (GAS). The low prevalence of GAS with intermediate susceptibility to erythromycin and resistance to doxycycline by a majority of the GAS emphasise the need for regular monitoring of antibiotic susceptibility of GAS.
authors.affiliation: Department of Microbiology and Immunology, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania.
authors.forename: F S
authors.initials: FS
authors.lastname: Mhalu
authors.forename: T
authors.initials: T
authors.lastname: Hofstad
mesh_terms: D004352:Drug Resistance, Microbial; D005500:Follow-Up Studies; D006761:Hospitals; D006801:Humans; D008826:Microbial Sensitivity Tests; D013297:Streptococcus pyogenes / Q000187:drug effects* / Q000302:isolation & purification; D013636:Tanzania