Magnetic resonance imaging of human brain function. Principles, practicalities, and possibilities.
This article presents a review of functional magnetic resonance (fMR) imaging. Included are four sections that address the principles, practicalities, and potentials of fMR imaging. The current types of hemodynamic contrast available with fMR imaging, including blood volume, perfusion, and oxygenation, are discussed. Technical issues of fMR imaging, including interpretability and sensitivity, are described, and several currently unresolved issues are addressed. Also reviewed are commonly used fMR imaging platforms and clinical and research applications.
Bandettini
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Biophysics Research Institute, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA.
Wong
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D001921:Brain / Q000033:anatomy & histology* / Q000502:physiology*; D006439:Hemodynamics; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods