Immunologic considerations in the child with recurrent or persistent sinusitis.
The diagnosis and management of chronic sinusitis in children represents a difficult challenge for the clinician. Part of the problem stems from the fact that normal children have many upper respiratory infections and it is sometimes difficult to determine whether the upper respiratory symptoms a child experiences with these infections are consistent with a normal number of "routine" childhood infections or whether there is a more significant problem. The issue is complicated by the fact that sinus infections in children may not have the same clinical manifestations as similar infections in adults. This review focuses on the pathophysiology of persistent and chronic sinus infections in children. Particular emphasis is placed on the potential role for allergic and/or immunologic disorders in children with chronic sinus problems.
Herrod
H G
HG
Crippled Children's Foundation Research Center, Le Bonheur Children's Medical Center, Memphis, TN 38103, USA.
D002648:Child; D002908:Chronic Disease; D006801:Humans; D012008:Recurrence; D012852:Sinusitis / Q000276:immunology* / Q000503:physiopathology*