Mechanisms of immunity to the respiratory pathogen Bordetella pertussis in normal and gene knockout mice: clearance of primary infection is not enhanced by therapeutic interleukin-12.
Mahon
B P
BP
Department of Biology, National University of Ireland at Maynooth, Co. Kildare, Ireland.
Ryan
M
M
Griffin
F
F
Mills
K H
KH
D000336:Aerosols; D000818:Animals; D001886:Bordetella pertussis / Q000276:immunology*; D007274:Injections, Intraperitoneal; D018664:Interleukin-12 / Q000008:administration & dosage / Q000627:therapeutic use*; D008168:Lung / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D018345:Mice, Knockout; D017471:Receptors, Interferon / Q000172:deficiency / Q000235:genetics / Q000502:physiology*; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000627:therapeutic use; D012016:Reference Values; D018417:Th1 Cells / Q000276:immunology; D018418:Th2 Cells / Q000276:immunology; D014917:Whooping Cough / Q000276:immunology* / Q000517:prevention & control / Q000628:therapy; D000096743:Interferon gamma Receptor
D000336:Aerosols; D018664:Interleukin-12; D017471:Receptors, Interferon; D011994:Recombinant Proteins; D000096743:Interferon gamma Receptor