Disappearance of the 'no-reflow' phenomenon after adjunctive intracoronary administration of nicorandil in a patient with acute myocardial infarction.
Adjunctive intracoronary administration of nicorandil, an ATP-sensitive potassium channel opener, after successful coronary revascularization was performed in a 54-year-old patient with acute myocardial infarction. The 'no-reflow' phenomenon disappeared after nicorandil administration and significant functional recovery of the infarcted myocardium was achieved. This suggests that nicorandil could eliminate the 'no-reflow' phenomenon after successful coronary revascularization.
Sakata
Y
Y
Cardiovascular Division, Osaka Police Hospital, Japan.
Kodama
K
K
Ishikura
F
F
Komamura
K
K
Hasegawa
S
S
Sakata
Y
Y
Hirayama
A
A
D003326:Coronary Circulation / Q000187:drug effects*; D003331:Coronary Vessels; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D015425:Myocardial Reperfusion; D009536:Niacinamide / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D020108:Nicorandil; D015221:Potassium Channels / Q000819:agonists*; D015912:Thrombolytic Therapy; D014463:Ultrasonography
D015221:Potassium Channels; D009536:Niacinamide; D020108:Nicorandil