title: Multiple giant fibroadenomas: clinical presentation and radiologic findings.
abstract: We describe the case of a 25-year-old Caucasian woman suffering from unilateral enlargement of the breast. Morphologic evaluation of various imaging modalities including mammography, ultrasound, and magnetic resonance imaging suggested a benign tumor embedded in stromal tissue. The time course of the Gd-DTPA uptake in dynamic magnetic resonance imaging, however, was also compatible with a malignant lesion. Postoperative pathological examination revealed multiple giant fibroadenomas, a rare disease, usually encountered in black female adolescents. Radiologic presentation, differential diagnosis, and morphologic findings are discussed, and a review of the literature is contained herein.
authors.affiliation: Department of Diagnostic Radiology, University of Freiburg, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Schneider
authors.forename: J
authors.initials: J
authors.lastname: Laubenberger
authors.forename: F
authors.initials: F
authors.lastname: Kommoss
authors.forename: H
authors.initials: H
authors.lastname: Madjar
authors.forename: K
authors.initials: K
authors.lastname: Gröne
authors.forename: M
authors.initials: M
authors.lastname: Langer
mesh_terms: D000328:Adult; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology*; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology*; D005682:Gadolinium; D006801:Humans; D008279:Magnetic Resonance Imaging; D008327:Mammography; D004369:Pentetic Acid / Q000493:pharmacokinetics; D013997:Time Factors; D016217:Ultrasonography, Mammary
chemical_list: D004369:Pentetic Acid; D005682:Gadolinium