title: [Ovarian activity of Drosophila melanogaster Meigen (Diptera), during a chronic intoxication with four fungicides: anatomical and cytological study].
abstract: Two types of reactions were observed on the alteration of Drosophila vitellogenesis by the four fungicides used in this study. Dithane M45 resulted in stimulation associated with egg retention. However, the other three fungicides (Benlate, Bouillie bordelaise and Euparène) resulted in inhibition to a varying degree. Although the inhibition was comparatively limited due to Benlate it induced an egg retention. The inhibition was very high due to Bouillie bordelaise and Euparène. With Bouillie bordelaise an egg retention occured together with the reduction of vitellogenesis and caused an increase in the rate of the follicle resorption. The latter depended on the duration of treatment. With Euparène, no egg retention was observed and the toxicity was only noticed on vitellogenesis.
authors.affiliation: Laboratoire Reproduction, Développement de l'Insecte, Université de Paris Sud, Orsay, France.
authors.forename: D
authors.initials: D
authors.lastname: Marchal-Ségault
authors.forename: G
authors.initials: G
authors.lastname: Laugé
mesh_terms: D000814:Aniline Compounds / Q000506:poisoning; D000818:Animals; D001542:Benomyl / Q000506:poisoning; D019327:Copper Sulfate / Q000506:poisoning; D004331:Drosophila melanogaster / Q000033:anatomy & histology / Q000187:drug effects*; D005260:Female; D005659:Fungicides, Industrial / Q000506:poisoning*; D008344:Maneb / Q000506:poisoning; D010053:Ovary / Q000187:drug effects*; D014818:Vitellogenesis / Q000187:drug effects*; D015038:Zineb / Q000506:poisoning
chemical_list: D000814:Aniline Compounds; D005659:Fungicides, Industrial; D008344:Maneb; C016370:dichlofluanid; D019327:Copper Sulfate; C013099:mancozeb; D001542:Benomyl; D015038:Zineb