title: [Successful treatment of fulminant myocarditis with the biventricular MEDOS Assist System (MEDOS HIA-VAD)].
abstract: BACKGROUND
  Successful weaning from biventricular mechanical support with full recovery of the myocardial function is extremely rare in fulminant myocarditis. We report on our experience with the new MEDOS HIA ventricular assist device.
  
  
  RESULTS
  We used the MEDOS assist system to support a 30-year-old woman with profound circulatory impairment caused by acute myocarditis. The device provided adequate hemodynamics and recovery of myocardial function. Despite anticoagulation therapy we had to change either the left or right ventricular pump chamber because of clot formation on the surface of the outflow tract. On the 14th postoperative day a surgical reintervention was necessary for bleeding from the cannulation site of the pulmonary artery. After 17 days the myocardial function had recovered and we could remove the assist system. The following parameters were measured before implantation of the MEDOS assist system and after weaning from circulatory support: ejection fraction 15 vs. 45%, cardiac index 0.7 vs. 2.6 L/min/m2, arterial pressure (systolic/diastolic/mean) 81/55/66 vs. 113/66/82 mm Hg, pulmonary artery pressure 33/25/29 vs. 34/20/28 mm Hg, pulmonary capillary wedge pressure 24 vs. 19 mm Hg.
  
  
  CONCLUSIONS
  Despite severe cardiac failure in fulminant myocarditis requiring biventricular mechanical support full recovery of the myocardium is possible.
authors.affiliation: Abteilung für Herz-und Gefässchirurgie Albert-Ludwigs-Universität.
authors.forename: J
authors.initials: J
authors.lastname: Martin
authors.forename: K
authors.initials: K
authors.lastname: Sarai
authors.forename: M
authors.initials: M
authors.lastname: Yoshitake
authors.forename: M
authors.initials: M
authors.lastname: Schindler
authors.forename: G
authors.initials: G
authors.lastname: Hasenfuss
authors.forename: A
authors.initials: A
authors.lastname: van de Loo
authors.forename: F
authors.initials: F
authors.lastname: Born
authors.forename: F
authors.initials: F
authors.lastname: Beyersdorf
mesh_terms: D000328:Adult; D019544:Equipment Failure Analysis; D005260:Female; D006353:Heart-Assist Devices; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D009200:Myocardial Contraction / Q000502:physiology; D009205:Myocarditis / Q000503:physiopathology / Q000601:surgery*; D011183:Postoperative Complications / Q000503:physiopathology / Q000601:surgery; D012086:Reoperation; D016896:Treatment Outcome