[Eosinophil cationic protein in persons with contact allergy to disinfectants].
The concentration of eosinophil cationic protein (ECP) in blood serum was determined in 53 health service workers (women) with contact allergy to disinfectants and in 16 healthy women using a radioimmunological method. The mean ECP concentration in the study group accounted for 7.518 micrograms/l, and in the control group 4.893 micrograms/l. The concentration of 8.403 micrograms/l (the mean concentration in the control group + 2 SD) was taken as a cut off concentration value. In 17 (32.1%) persons with contact dermatitis, pathological ECP values were found. An increased ECP was observed in persons with positive results of prick test, especially in the case of Dermatophagoides, pollens and latex as well as in those with increased total IgE concentration. Our results indicate the involvement of immediate allergy in the incidence of contact allergy to disinfectants.
Kieć-Swierczyńska
M
M
Przychodni Chorób Zawodowych, Instytutu Medycyny Pracy, Lodzi.
Krecisz
B
B
Krajewska
B
B
Szymczak
W
W
D000328:Adult; D001798:Blood Proteins / Q000032:analysis*; D017449:Dermatitis, Allergic Contact / Q000097:blood* / Q000175:diagnosis / Q000209:etiology / Q000276:immunology; D009783:Dermatitis, Occupational / Q000097:blood* / Q000175:diagnosis / Q000209:etiology / Q000276:immunology; D004202:Disinfectants / Q000009:adverse effects; D047091:Eosinophil Granule Proteins; D005260:Female; D006282:Health Personnel; D006801:Humans; D007073:Immunoglobulin E / Q000032:analysis; D018836:Inflammation Mediators / Q000032:analysis*; D008875:Middle Aged; D012260:Ribonucleases; D012882:Skin Tests
D001798:Blood Proteins; D004202:Disinfectants; D047091:Eosinophil Granule Proteins; D018836:Inflammation Mediators; D007073:Immunoglobulin E; D012260:Ribonucleases