title: Mapdiff: determining differences between two genomic maps.
abstract: BACKGROUND
  When inspecting two maps of a chromosome or chromosomal region derived by similar or different methodologies, a computer-generated description of their differences is valuable, both to guide laboratory research as well as to assist version control. Our program, Mapdiff, can be used to compare two independently derived maps, or two revisions of the same map. Its usefulness increases in proportion to the percentage of shared objects between the two maps. Mapdiff uses a greedy algorithm to determine differences between shared objects.
  
  
  RESULTS
  We illustrate Mapdiff's use in comparing the publicly available STS-content and radiation hybrid maps of human chromosome 12.
  
  
  BACKGROUND
  Freely available, (source, executables for Windows/DOS and Sun Solaris, documentation) on request from the author.
authors.affiliation: Center for Medical Informatics, Yale University School of Medicine, New Haven, CT 06510, USA. Prakash.Nadkarni@Yale.edu
authors.forename: P M
authors.initials: PM
authors.lastname: Nadkarni
mesh_terms: D000465:Algorithms; D002874:Chromosome Mapping; D002881:Chromosomes, Human, Pair 12 / Q000235:genetics; D008040:Genetic Linkage; D005819:Genetic Markers; D015894:Genome, Human; D006801:Humans; D016324:Sequence Tagged Sites; D012984:Software; D012985:Software Design
chemical_list: D005819:Genetic Markers