title: Rapidly-growing ectopic pituitary adenoma within the sphenoid sinus--case report.
abstract: A 75-year-old male with left abducens nerve paresis presented with an ectopic pituitary adenoma invading the posterior wall of the sphenoid sinus. The sphenoidal mass grew rapidly for 6 months with left ophthalmoplegia and was partially removed via the transsphenoidal approach. The histological examination showed a benign pituitary adenoma, but the MIB-1 proliferating cell index was 6.8%, reflecting the clinically malignant behavior. The symptom gradually improved without tumor regrowth over 1.5 years after conventional irradiation.
authors.affiliation: Department of Neurosurgery, Shinshu University School of Medicine, Nagano.
authors.forename: T
authors.initials: T
authors.lastname: Horiuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: T
authors.initials: T
authors.lastname: Unoki
authors.forename: A
authors.initials: A
authors.lastname: Yokoh
mesh_terms: D000236:Adenoma / Q000473:pathology* / Q000628:therapy; D000368:Aged; D002828:Choristoma / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008297:Male; D010911:Pituitary Neoplasms / Q000473:pathology* / Q000628:therapy; D013101:Sphenoid Sinus