Microencapsulation of neonatal porcine islets: long-term reversal of diabetes in nude mice and in vitro protection from human complement mediated cytolysis.
Korbutt
G S
GS
Surgical-Medical Research Institute, University of Alberta, Edmonton, Canada.
Elliott
J F
JF
Ao
Z
Z
Flashner
M
M
Warnock
G L
GL
Rajotte
R V
RV
D000464:Alginates; D000818:Animals; D000831:Animals, Newborn; D001672:Biocompatible Materials; D001786:Blood Glucose / Q000378:metabolism; D002214:Capsules; D002478:Cells, Cultured; D003165:Complement System Proteins / Q000276:immunology*; D003602:Cytotoxicity, Immunologic; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy*; D006085:Graft Survival; D006801:Humans; D016381:Islets of Langerhans Transplantation / Q000379:methods* / Q000502:physiology; D051379:Mice; D008819:Mice, Nude; D013552:Swine; D013997:Time Factors; D014183:Transplantation, Heterologous / Q000379:methods* / Q000502:physiology
D000464:Alginates; D001672:Biocompatible Materials; D001786:Blood Glucose; D002214:Capsules; D003165:Complement System Proteins