title: Association of Chlamydia trachomatis antibodies with genital contact disease in women in Benin City, Nigeria.
abstract: The involvement of Chlamydia trachomatis in genital contact disease was assessed by measuring anti-chlamydial antibodies in the serum of 780 women aged 16-40 years using the indirect haemagglutination test. These were compared to a control population consisting of 250 consenting housewives visiting General Practice Clinic (GPC) for other medical reasons. Test results showed an overall prevalence of 47% for indirect haemagglutination (IHA) chlamydial antibodies in women with genital contact disease. The average IHA titre was 143. The age group 21-25 years recorded the highest prevalence of 54%, with 55% giving a titre > or = 64. The control population gave a prevalence of 12% with no sample recording a titre < or = 64. These findings may indicate a need to routinely conduct investigations for chlamydial infection in all cases of genital contact disease in our environment.
authors.affiliation: Department of Biochemistry, University of Benin, Nigeria.
authors.forename: A A
authors.initials: AA
authors.lastname: Azenabor
authors.forename: N O
authors.initials: NO
authors.lastname: Eghafona
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000907:Antibodies, Bacterial / Q000032:analysis*; D002690:Chlamydia Infections / Q000175:diagnosis* / Q000453:epidemiology / Q000276:immunology*; D002692:Chlamydia trachomatis / Q000276:immunology*; D005260:Female; D006386:Hemagglutination Tests; D006801:Humans; D009549:Nigeria / Q000453:epidemiology; D015995:Prevalence; D016036:Seroepidemiologic Studies; D012749:Sexually Transmitted Diseases / Q000175:diagnosis* / Q000453:epidemiology / Q000382:microbiology*
chemical_list: D000907:Antibodies, Bacterial