title: [Extracorporeal membrane oxygenation (ECMO). II. The development of an experimental model in newborn lambs].
abstract: OBJECTIVE
  Extracorporeal membrane oxygenation (ECMO) is a technique used for cardiorespiratory support in the treatment of newborns with severe respiratory insufficiency. ECMO has not been used yet in newborns in Spain. The aim of this work was to develop an experimental veno-arterial ECMO model in newborn lambs for training the NICU medical and nursing staff before the clinical application of this technique.
  
  
  METHODS
  Six newborn lambs were anesthetized, traqueotomized and connected to a neonatal ventilator. The right jugular vein and left carotid artery were cannulated and the catheters were located in the right atrium and aortic arch, respectively. A venous-arterial ECMO was performed during three hours, with an experimental ECMO circuit developed by us. Arterial pH and blood gases, systemic and airway pressures, heart rate, and rectal temperature were monitored.
  
  
  RESULTS
  The experimental ECMO circuit developed by use had a very low cost, but was capable of maintaining adequate gas exchange, acid-base balance and a normal rectal temperature.
  
  
  CONCLUSIONS
  The development of an experimental ECMO model in newborn lambs may allow the establishment of an initial training program and to maintain the expertise of the NICU staff of a perinatal center planning to start an ECMO program.
authors.affiliation: Unidad Neonatal, Hospital de Cruces, Facultad de Medicina, Universidad del País Vasco, Barakaldo, Bizkaia.
authors.forename: A
authors.initials: A
authors.lastname: Valls i Soler
authors.forename: F J
authors.initials: FJ
authors.lastname: Alvarez Díaz
authors.forename: E
authors.initials: E
authors.lastname: Gastiasoro Cuesta
authors.forename: A
authors.initials: A
authors.lastname: Arnaiz Renedo
authors.forename: B
authors.initials: B
authors.lastname: Fernández Ruanova
authors.forename: L F
authors.initials: LF
authors.lastname: Alfonso Sánchez
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D004867:Equipment Design; D015199:Extracorporeal Membrane Oxygenation / Q000379:methods*; D012107:Research Design; D012120:Respiration Disorders / Q000534:rehabilitation*; D012756:Sheep; D013997:Time Factors