title: Villous adenocarcinoma of the duodenum invading the ampulla of Vater case report and review of literature.
abstract: We report a case of villous adenocarcinoma of duodenum arising from the ampulla of Vater with a review of the literature. Although preoperative endoscopic biopsies were performed, no malignancy was identified. Because of the pathological uncertainty we decided to perform a pylorus-preserving pancreatoduodenectomy. Microscopic examination demonstrated glandular dysplasia with aspects of villous adenoma and well differentiated adenocarcinoma. We conclude that both in malignant cases and in cases with uncertain diagnosis a pylorus-preserving pancreatoduodenectomy is the best surgical treatment because it results in better 5 year survival.
authors.affiliation: Department of Surgery, University of Catania, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Catania
authors.forename: F
authors.initials: F
authors.lastname: Cardi
authors.forename: M
authors.initials: M
authors.lastname: Migliore
authors.forename: G
authors.initials: G
authors.lastname: Romeo
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014670:Ampulla of Vater; D001706:Biopsy; D002760:Cholangiopancreatography, Endoscopic Retrograde; D003138:Common Bile Duct Neoplasms / Q000473:pathology*; D004379:Duodenal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D016577:Pancreaticoduodenectomy; D016019:Survival Analysis