title: Carcinoma of the esophagus treated with radical chemoradiation 19 years after irradiation for recurrent breast cancer.
abstract: Prior irradiation to a site is a relative and often absolute contraindication to further irradiation because the tolerance dose of normal tissues is usually exceeded and therefore the risk of serious long-term side-effects is high. This case report describes radical salvage chemoradiation for an esophageal carcinoma in a patient who had prior high-dose neck and chest wall irradiation for the management of a breast cancer 19 years previously.
authors.affiliation: Department of Radiation Oncology, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia.
authors.forename: C
authors.initials: C
authors.lastname: MacLeod
authors.forename: E
authors.initials: E
authors.lastname: Moylan
authors.forename: G L
authors.initials: GL
authors.lastname: Falk
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000532:radiotherapy*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000532:radiotherapy*; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000532:radiotherapy*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000532:radiotherapy*; D004947:Esophagus / Q000528:radiation effects*; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000532:radiotherapy*; D009381:Neoplasms, Radiation-Induced / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000532:radiotherapy*; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000532:radiotherapy*; D016879:Salvage Therapy; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D002945:Cisplatin; D005472:Fluorouracil