Identification of an acetolactate synthase small subunit gene in two eukaryotes.
Acetolactate synthase catalyses the first step in branched-chain amino acid biosynthesis. The bacterial enzyme contains two large and two small subunits but there is only limited and circumstantial evidence for a small subunit in the eukaryotic enzyme. Here this evidence is summarised and protein sequences of two putative eukaryotic small subunits, from a yeast and a red alga, are presented.
Duggleby
R G
RG
Centre for Protein Structure, Function and Engineering, Department of Biochemistry, University of Queensland, Brisbane, Australia. duggleby@biosci.uq.edu.au
D000095:Acetolactate Synthase / Q000235:genetics* / Q000378:metabolism*; D000595:Amino Acid Sequence; D001951:Brevibacterium / Q000201:enzymology / Q000235:genetics; D002736:Chloroplasts / Q000378:metabolism; D017124:Conserved Sequence; D003352:Corynebacterium / Q000201:enzymology / Q000235:genetics; D005057:Eukaryotic Cells / Q000201:enzymology*; D008969:Molecular Sequence Data; D000461:Rhodophyta / Q000201:enzymology / Q000235:genetics; D012441:Saccharomyces cerevisiae / Q000201:enzymology / Q000235:genetics; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid
D000095:Acetolactate Synthase