A case of chrysiasis.
Chrysiasis and chrysoderma are terms used to describe permanent pigmentation of the skin due to the parenteral administration of gold salts. A case of chrysiasis, including a photomicrograph of the characteristic orange-red birefringence of gold in tissue when viewed under cross-polarized light, is presented. A review of the literature on the pathogenesis of the pigmentation seen in this disorder is also presented.
Miller
M L
ML
Department of Dermatology, National Naval Medical Center, Bethesda, Maryland, USA.
Harford
R R
RR
Yeager
J K
JK
Johnson
F
F
D000368:Aged; D018501:Antirheumatic Agents / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D001718:Birefringence; D005260:Female; D006046:Gold / Q000032:analysis; D006801:Humans; D008855:Microscopy, Electron, Scanning; D010859:Pigmentation Disorders / Q000139:chemically induced* / Q000473:pathology; D012867:Skin / Q000737:chemistry / Q000473:pathology*; D013052:Spectrometry, X-Ray Emission
D018501:Antirheumatic Agents; D006046:Gold