title: Effects of soft X-ray irradiation on NK cell activity and the percentage of asialo GM1-positive cells in spleen cells of mice.
abstract: Effects of soft X-ray irradiation on the natural killer (NK) cell activity and the percentage of asialo GM1-positive cells of spleen cells in mice were investigated by using a soft X-ray generator intended for non-destructive radiological examination. Soft X-ray irradiation in graded doses of more than 25.8 mC/kg indicated dose dependent reductions in the NK cell activity in the spleen of irradiated mice. Significant reductions in the population of asialo GM1-positive cells in spleen cells were also observed. These results suggest that a soft X-ray generator could also be useful in immuno-irradiation studies.
authors.affiliation: Department of Biotechnology, Faculty of Engineering, Kyoto Sangyo University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Takeuchi
authors.forename: H
authors.initials: H
authors.lastname: Shibata
mesh_terms: D000818:Animals; D004307:Dose-Response Relationship, Radiation; D005260:Female; D005677:G(M1) Ganglioside / Q000032:analysis*; D007694:Killer Cells, Natural / Q000276:immunology / Q000528:radiation effects*; D051379:Mice; D008810:Mice, Inbred C57BL; D013154:Spleen / Q000166:cytology / Q000528:radiation effects*; D014965:X-Rays
chemical_list: D005677:G(M1) Ganglioside; C018835:asialo GM1 ganglioside