Anti-CD4/CyA therapy causes prevention of autoimmune but not allogeneic destruction of grafted islets in BB rats.
Kuttler
B
B
Institute of Diabetes, G. Katsch Karisburg, University of Greifswald, Germany.
Rösing
K
K
Hahn
H J
HJ
D000818:Animals; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D015551:Autoimmunity; D001786:Blood Glucose / Q000378:metabolism; D015704:CD4 Antigens / Q000276:immunology*; D015496:CD4-Positive T-Lymphocytes / Q000276:immunology; D016572:Cyclosporine / Q000627:therapeutic use*; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000601:surgery*; D006084:Graft Rejection / Q000517:prevention & control; D007515:Islets of Langerhans / Q000276:immunology* / Q000502:physiology; D008285:Major Histocompatibility Complex; D051381:Rats; D011913:Rats, Inbred BB; D011917:Rats, Inbred Lew; D014184:Transplantation, Homologous / Q000276:immunology*; D014185:Transplantation, Isogeneic / Q000276:immunology
D000911:Antibodies, Monoclonal; D001786:Blood Glucose; D015704:CD4 Antigens; D016572:Cyclosporine