Chloroquine-induced vitiligo-like depigmentation.
A 6-year-old girl of Ethiopian origin with atopic eczema from the age of 2 years is reported. Prior to a visit to her grandparents in Ethiopia, she received 250 mg chloroquine weekly as prophylaxis against malaria. Three weeks later she developed sharply demarcated depigmentation on the face, especially in the peritoneal area. On returning home to Norway, the medication was discontinued and after a few weeks the first repigmentation was noticed. Complete repigmentation was observed 1 year after cessation of chloroquine therapy.
Selvaag
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Department of Dermatology, Ullevaal Hospital, Oslo, Norway.
D000962:Antimalarials / Q000009:adverse effects*; D002648:Child; D002738:Chloroquine / Q000009:adverse effects*; D005002:Ethiopia / Q000208:ethnology; D005148:Facial Dermatoses / Q000139:chemically induced*; D005260:Female; D006801:Humans; D014820:Vitiligo / Q000139:chemically induced*
D000962:Antimalarials; D002738:Chloroquine