[Balloon-occluded intraarterial infusion therapy for advanced uterine cervical cancer: usefulness of four-lumen double balloon catheter].
We have devised a new catheter with four-lumen and a double balloon (4L-DB), which has made it easy to find feeding arteries and enhanced the local concentration of drugs. At first, two 4L-DB catheters were inserted into the contralateral internal iliac artery, via the bilateral femoral arteries. Then, the distal balloon was set in the superior gluteal artery and the proximal balloon in the internal iliac artery. Between the two inflated balloons, anti-cancer drugs (CDDP 100mg, Therarubicin 20mg, MMC 20mg) were infused to the bilateral uterine arteries during 30 minutes via side holes. The response rate for this therapy was 71%, and 3 cases of complete response (CR) were obtained. No severe side effects were observed. In conclusion, the 4L-DB catheter may be an exceedingly efficient method of local anticancer drug infusion.
Yamamoto
K
K
Department of Radiology, Osaka Medical College.
Shimizu
T
T
Narabayashi
I
I
D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002404:Catheterization / Q000295:instrumentation*; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D002583:Uterine Cervical Neoplasms / Q000098:blood supply / Q000628:therapy*
D000970:Antineoplastic Agents