[Are self-perceivable neuropsychological deficits in patients with neuroses or personality disorder diagnoses indicative of later schizophrenia?].
For the first time, the present study assessed the achievable predictive value of early self-experienced neuropsychological deficits for the fater development of schizophrenia. Ninety-six patients with DSM-III-R diagnoses mainly of the formerly neurotic or personality disordered field, of whom 81% had shown such basic disorders at the time of the index examination and therefore were classified as persons at high risk of developing schizophrenia, were re-examined for schizophrenia. After an average follow-up period of about 8 years, more than half of the re-examined sample had developed a schizophrenic disorder according to DSM-III-R. The outcome of schizophrenia versus no schizophrenia was predicted correctly in 77% of cases by the presence or absence of self-experienced disturbances of perception, thought, speech or action.
Klosterkötter
J
J
Klinik für Psychiatrie und Psychotherapie, Universität zu Köln.
Gross
G
G
Huber
G
G
Steinmeyer
E M
EM
D000293:Adolescent; D000328:Adult; D001364:Awareness; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000145:classification / Q000175:diagnosis / Q000523:psychology*; D009483:Neuropsychological Tests; D009497:Neurotic Disorders / Q000145:classification / Q000175:diagnosis / Q000523:psychology*; D010468:Perceptual Disorders / Q000145:classification / Q000175:diagnosis / Q000523:psychology; D010554:Personality Disorders / Q000145:classification / Q000175:diagnosis / Q000523:psychology*; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D012559:Schizophrenia / Q000145:classification / Q000175:diagnosis*; D012564:Schizophrenic Language; D012565:Schizophrenic Psychology; D012569:Schizotypal Personality Disorder / Q000145:classification / Q000175:diagnosis / Q000523:psychology*; D012803:Sick Role; D013850:Thinking