title: [Lyell syndrome after amoxicillin administration in a 2 year old child].
abstract: The authors report a toxic epidermal necrolysis (TEN) due to ampicillin (Agram) in a 2-year-old child. During the acute phase a septic syndrome occurred. The severity of the clinical and biological symptoms led to the administration of antibiotics, their systematic use remaining controversial. Recovery was favourable in a paediatric burn centre. Sequelae were minor. TEN, the physiopathological mechanism of which remaining still unknown, may carry a vital risk.
authors.affiliation: Service d'anesthésie-réanimation chirurgicale, Hôtel Dieu, Nantes, France.
authors.forename: M
authors.initials: M
authors.lastname: Surbled
authors.forename: C
authors.initials: C
authors.lastname: Lejus
authors.forename: B
authors.initials: B
authors.lastname: Milpied
authors.forename: M
authors.initials: M
authors.lastname: Pannier
authors.forename: R
authors.initials: R
authors.lastname: Souron
mesh_terms: D000658:Amoxicillin / Q000009:adverse effects*; D000768:Anesthesia, General / Q000379:methods; D000818:Animals; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002675:Child, Preschool; D006224:Cricetinae; D006801:Humans; D015278:Intensive Care Units, Pediatric; D008297:Male; D013262:Stevens-Johnson Syndrome / Q000209:etiology* / Q000628:therapy
chemical_list: D000900:Anti-Bacterial Agents; D000658:Amoxicillin