title: [Neonatal esophago-gastro-duodenoscopy. Apropos of 123 examinations performed on 107 newborn infants].
abstract: Upper gastrointestinal endoscopy is frequently used in the neonatal period. The aim of this study was to assess the frequency of the different lesions occurring as well as to precise indications of upper gastrointestinal endoscopy in neonates.
  
  
  METHODS
  A retrospective study including 107 neonates referred between October 1986 and April 1995 has been achieved in the pediatric gastroenterology unit of the Lille University Hospital. Various factors were analysed: gestational age, sex, reasons for endoscopy and macroscopic lesions observed. Three groups were constituted according to macroscopic findings; group I: normal aspect (n = 22); group II: isolated esophagitis (n = 27); group III: esogastritis or gastroduodenitis or esogastroduodenitis (n = 38). Chi 2 test was performed for statistical analysis.
  
  
  RESULTS
  Signs recalling esophagitis (cry during feeding) were more frequent in group II than in group III: 37% vs 13% (P < 0.03). The neonates undergoing endoscopy for life-threatening events were more frequent in group I than in group II or III, respectively: 59% vs 15% (P < 0.01) and 59% vs 8% (P < 10(-4). Upper gastrointestinal endoscopy led to a precise diagnosis in 80% of the neonates. However 95% of those examined for hematemesis presented macroscopic lesions.
  
  
  CONCLUSIONS
  Hematemesis and suspicion of esophagitis are good indications for upper gastrointestinal endoscopy in neonatal period. In life-threatening events and suspicion of pyloric stenosis, upper gastrointestinal endoscopy is only complementary of more contributive other examinations.
authors.affiliation: Service de pédiatrie, gastroentérologie pédiatrique et génétique médicale, hôpital Claude-Huriez, Lille, France.
authors.forename: P S
authors.initials: PS
authors.lastname: Ganga-Zandzou
authors.forename: S
authors.initials: S
authors.lastname: Ategbo
authors.forename: L
authors.initials: L
authors.lastname: Michaud
authors.forename: F
authors.initials: F
authors.lastname: Gottrand
authors.forename: J P
authors.initials: JP
authors.lastname: Farriaux
authors.forename: D
authors.initials: D
authors.lastname: Turck
mesh_terms: D004384:Duodenoscopy / Q000706:statistics & numerical data; D004935:Esophageal Diseases / Q000175:diagnosis* / Q000453:epidemiology; D004941:Esophagitis / Q000175:diagnosis / Q000453:epidemiology; D004943:Esophagogastric Junction / Q000473:pathology; D004945:Esophagoscopy / Q000706:statistics & numerical data; D005260:Female; D005602:France / Q000453:epidemiology; D005767:Gastrointestinal Diseases / Q000175:diagnosis / Q000453:epidemiology; D005773:Gastroscopy / Q000706:statistics & numerical data; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D012189:Retrospective Studies