Viral RNA export.
Viruses can express intron-containing and intronless mRNAs, which are exported by alternative pathways. The study of the nuclear export of these unconventional mRNAs can provide key insights into the normal process of nuclear export and the alternative pathways provide an attractive target for the development of specific antiviral therapies.
Hope
T J
TJ
Salk Institute for Biological Studies 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
D000595:Amino Acid Sequence; D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology; D001692:Biological Transport; D002467:Cell Nucleus / Q000378:metabolism; D015694:Gene Products, rev / Q000378:metabolism; D015497:HIV-1 / Q000737:chemistry; D006801:Humans; D007438:Introns; D008969:Molecular Sequence Data; D015394:Molecular Structure; D021382:Protein Sorting Signals / Q000737:chemistry; D011506:Proteins / Q000378:metabolism; D012333:RNA, Messenger / Q000378:metabolism; D012367:RNA, Viral / Q000378:metabolism*; D014764:Viral Proteins / Q000378:metabolism; D054321:rev Gene Products, Human Immunodeficiency Virus
D000998:Antiviral Agents; D015694:Gene Products, rev; D021382:Protein Sorting Signals; D011506:Proteins; D012333:RNA, Messenger; D012367:RNA, Viral; D014764:Viral Proteins; D054321:rev Gene Products, Human Immunodeficiency Virus