[The corrective action of limontar in metabolic disorders in the mother-fetus system caused by ethanol exposure during pregnancy].
It was established in experiments on nonbred albino rats that injection of limontar (1 mg/kg) in the fetal period of pregnancy in alcoholic intoxication (6 g/kg) leads to weight loss by the female, normalization of the character of behavior and metabolic shifts in the organism, and removal of the symptoms of excitation of the sympathetic link of cardiovascular system regulation. No harmful effect of limontar on the mother-fetus biosystem was detected.
Sheveleva
G A
GA
Filimonov
V G
VG
Akin'shina
V A
VA
Uroshleva
L A
LA
Chirkova
E M
EM
Koppel'
M A
MA
Korneev
A A
AA
D000435:Alcoholic Intoxication / Q000097:blood / Q000188:drug therapy / Q000196:embryology; D000818:Animals; D002951:Citrates / Q000009:adverse effects / Q000627:therapeutic use*; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D004622:Embryo, Mammalian / Q000187:drug effects / Q000378:metabolism; D000431:Ethanol / Q000633:toxicity*; D005260:Female; D008431:Maternal-Fetal Exchange / Q000187:drug effects* / Q000502:physiology; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000187:drug effects*; D051381:Rats; D013386:Succinates / Q000009:adverse effects / Q000627:therapeutic use*
D002951:Citrates; D004338:Drug Combinations; D013386:Succinates; C100829:limontar; D000431:Ethanol