[A case report on mitral valve replacement associated with antiphospholipid syndrome in systemic lupus erythematosus].
Mitral valve replacement (MVR) was performed on a 36-year-old woman for mitral valve regurgitation. The patient suffered from antiphospholipid syndrome (APLS) with systemic lupus erythematosus (SLE). The patient required 4 times plasma exchanges to prevent embolization to the cerebral arteries. A decrease in the anticardiolipin beta 2-glycoprotein I complex level was achieved and MVR was performed with a relatively good postoperative course. Anticoagulation therapy had been continued, but one year postoperatively the patient fell down a staircase and suffered acute epidural hematoma. Emergency operation was performed. The patient, however, died due to cerebral hemorrhage.
Araki
Y
Y
Department of Cardiovascular Surgery, Nagoya Second Red Cross Hospital, Japan.
Tajima
K
K
Shimomura
T
T
Abe
T
T
Yoshikawa
M
M
Io
A
A
Tuzuki
T
T
Suenaga
Y
Y
D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications*; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008943:Mitral Valve / Q000601:surgery; D008944:Mitral Valve Insufficiency / Q000209:etiology / Q000601:surgery*