[Chinese herbs nephropathy in the Kansai area: a warning report].
In 1993, Vanherweghem and his associates reported cases of rapidly progressive renal interstitial fibrosis in young women who were administered a slimming regimen including Chinese herbs. Subsequently, similar cases have been reported. In Japan, especially in the Kansai area, several cases of Chinese herbs nephropathy have already been reported. We experienced a patient suffering from Chinese herbs nephropathy (CHN), and further detected aristolochic acids from the Chinese herbs taken by the patient. Aristolochic acids are known to be causative agents of CHN. The danger of CHN should be noted as soon as possible and drugs containing aristolochic acids should be prohibited.
Tanaka
A
A
Department of Nephrology, Saiseikai Nakatsu Hospital, Osaka, Japan.
Shinkai
S
S
Kasuno
K
K
Maeda
K
K
Murata
M
M
Seta
K
K
Okuda
J
J
Sugawara
A
A
Yoshida
T
T
Nishida
R
R
Kuwahara
T
T
D034341:Aristolochic Acids; D004365:Drugs, Chinese Herbal / Q000009:adverse effects* / Q000737:chemistry; D005198:Fanconi Syndrome / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007564:Japan; D008875:Middle Aged; D010616:Phenanthrenes / Q000009:adverse effects* / Q000302:isolation & purification
D034341:Aristolochic Acids; D004365:Drugs, Chinese Herbal; D010616:Phenanthrenes; C000228:aristolochic acid I