Reversal of hyperglycemia in diabetic NOD mice by human proinsulin gene therapy.
Kasten-Jolly
J
J
Department of Surgery, Albany Medical College, NY 12208, USA.
Aubrey
M T
MT
Conti
D J
DJ
Rosano
T G
TG
Ross
J S
JS
Freed
B M
BM
D016475:3T3 Cells; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D017690:Cell Transplantation; D003001:Cloning, Molecular; D016572:Cyclosporine / Q000627:therapeutic use; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000628:therapy*; D005260:Female; D015316:Genetic Therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D049528:Insulin, Long-Acting / Q000627:therapeutic use; D008099:Liver / Q000473:pathology; D051379:Mice; D016688:Mice, Inbred NOD; D011384:Proinsulin / Q000096:biosynthesis / Q000235:genetics*; D014162:Transfection; D014184:Transplantation, Homologous
D001786:Blood Glucose; D007166:Immunosuppressive Agents; D049528:Insulin, Long-Acting; D016572:Cyclosporine; D011384:Proinsulin