title: Effect of racing on serum sodium and potassium concentrations and acid-base status of Alaskan sled dogs.
abstract: OBJECTIVE
  To examine the effect of participation in a long-distance race on serum electrolyte concentrations, estimated exchangeable cation content, and acid-base status of Alaskan sled dogs.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  9 male and 5 female, sexually intact, physically fit Alaska sled dogs between 18 and 48 months old.
  
  
  METHODS
  Body weight was recorded, and blood samples were collected from dogs before, during, and after a 300-mile race.
  
  
  RESULTS
  Serum sodium and potassium concentrations decreased during the race, as did serum total protein, albumin, and globulin concentrations and PCV. Effects on acid-base status were minimal. Body weight and estimated total exchangeable cation content in dogs also decreased significantly during the race.
  
  
  CONCLUSIONS
  Prolonged running is associated with decreases in serum cation concentration and estimated total exchangeable cation content in dogs, as in human beings and horses. However, the mechanism of the decrease in serum cation concentration likely differs among species. Clinical abnormalities associated with cation depletion were not observed in the dogs in this study.
authors.affiliation: Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus 43210-1089, USA.
authors.forename: K W
authors.initials: KW
authors.lastname: Hinchcliff
authors.forename: G A
authors.initials: GA
authors.lastname: Reinhart
authors.forename: J R
authors.initials: JR
authors.lastname: Burr
authors.forename: C J
authors.initials: CJ
authors.lastname: Schreier
authors.forename: R A
authors.initials: RA
authors.lastname: Swenson
mesh_terms: D000136:Acid-Base Equilibrium; D000818:Animals; D001774:Blood Chemical Analysis / Q000662:veterinary; D004285:Dogs / Q000097:blood*; D005260:Female; D008297:Male; D010805:Physical Conditioning, Animal / Q000502:physiology; D005082:Physical Exertion / Q000502:physiology*; D011188:Potassium / Q000097:blood*; D012420:Running / Q000502:physiology; D012964:Sodium / Q000097:blood*
chemical_list: D012964:Sodium; D011188:Potassium