[The immunocorrection with Aerosil-350 of the natural resistance of mice found under conditions of an elevated radiation background].
Experiments on the CBA mice that had been within 30 km of the Chernobyl NPP accident for 3 months revealed a decrease in the phagocytic and bactericidal properties of peritoneal macrophages accompanied with a disturbance in the production of interleukin-1 and a tumor necrosis factor responsible for the cell immunity. A single administration of a silicon-containing enterosorbent Aerosil-350 expedient to remove radionuclides and ensure the organism detoxication made it possible to correct and restore the affected cell and organism immunity for 7 days.
Ganova
L A
LA
Spivak
N Ia
NIa
Semernikov
V A
VA
D000284:Administration, Oral; D000818:Animals; D016061:Enterosorption; D004781:Environmental Exposure / Q000009:adverse effects*; D005720:Gamma Rays; D007111:Immunity, Cellular / Q000187:drug effects / Q000528:radiation effects; D007113:Immunity, Innate / Q000187:drug effects* / Q000528:radiation effects*; D017737:Macrophages, Peritoneal / Q000187:drug effects / Q000276:immunology / Q000528:radiation effects; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D011210:Power Plants; D018788:Radioactive Hazard Release; D012822:Silicon Dioxide / Q000008:administration & dosage*; D013997:Time Factors; D014455:Ukraine
D012822:Silicon Dioxide