Scanning alanine mutagenesis of the second Ig domain of Fc gamma RI indicates critical residues for ligand recognition.
McCarthy-Troke
M H
MH
Division of Biochemistry and Molecular Biology, University of Glasgow, Scotland.
Harrison
P T
PT
Campbell
I
I
Allen
J M
JM
D000409:Alanine; D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D019556:COS Cells; D017124:Conserved Sequence; D006801:Humans; D007074:Immunoglobulin G / Q000378:metabolism*; D008961:Models, Structural; D016297:Mutagenesis, Site-Directed; D017433:Protein Structure, Secondary; D017452:Receptors, IgG / Q000737:chemistry* / Q000378:metabolism*; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism; D014162:Transfection
D007074:Immunoglobulin G; D017452:Receptors, IgG; D011994:Recombinant Proteins; D000409:Alanine