Intramuscular myxoma and fibrous dysplasia of bone--Mazabraud's syndrome. A case report.
We present a case of Mazabraud's syndrome, a rare benign disease, with multiple intramuscular myxomas of the thoracic wall associated with fibrous dysplasia of bone. CT, MR imaging and ultrasonography (US) of the thorax showed 2 well circumscribed homogeneous intramuscular tumors. A US-guided needle biopsy with a large-core needle (2.0 mm) and a fine needle (0.8 mm) showed that the tumors were intramuscular myxomas with no sign of malignancy. 99mTc bone scintigraphy showed a markedly increased uptake in the right lower skull, and multiple smaller foci. CT of the skull revealed a right-sided unilateral bone thickening of the orbit and the ethmoidal cells, and right-sided exophthalmia. This case history suggests that patients with multiple intramuscular myxomas should be preoperatively examined for osseous lesions. A postoperative follow-up should also be performed to detect other soft-tissue myxomas not as yet clinically detectable, or rare osseous complications.
Court-Payen
M
M
Department of Ultrasound, Herlev Hospital, University of Copenhagen, Denmark.
Ingemann Jensen
L
L
Bjerregaard
B
B
Schwarz Lausten
G
G
Skjoldbye
B
B
D001707:Biopsy, Needle; D005004:Ethmoid Bone / Q000000981:diagnostic imaging; D005094:Exophthalmos / Q000175:diagnosis; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000175:diagnosis* / Q000000981:diagnostic imaging; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D009232:Myxoma / Q000175:diagnosis* / Q000000981:diagnostic imaging; D009915:Orbit / Q000000981:diagnostic imaging; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012886:Skull / Q000000981:diagnostic imaging; D013577:Syndrome; D013667:Technetium; D013899:Thoracic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
D019275:Radiopharmaceuticals; D013667:Technetium