Eye drop container delivery: a source of response variation?
Variations in response to topically applied ocular drugs (e.g. mydriatics and cycloplegics) and their possible aetiology have been studied previously. It appears that individual patient differences, external influencing factors and the characteristics of the particular drug may all govern the response. One factor worthy of note in this regard is the possibility of variation in the drug volume instilled. Single-use eye drop containers known as Minims are commonly used during ophthalmic diagnostic procedures. However, in this study the drop volume was shown to vary considerably, depending upon the angle at which the Minims container was held, the particular drug and the number of drops previously expelled from the unit.
German
E J
EJ
Department of Optometry, University of Bradford, West Yorkshire, UK.
Hurst
M A
MA
Wood
D
D
D004349:Drug Packaging / Q000592:standards; D009883:Ophthalmic Solutions / Q000008:administration & dosage*; D013500:Surface Tension; D014783:Viscosity
D009883:Ophthalmic Solutions