A brief overview of apoptosis.
Apoptosis, a characteristic type of cell death, plays important roles in tissue and organ development in ontogeny. It also relates to the occurrence of serious diseases such as virus infection, autoimmune disease and cancer. Furthermore many drugs such as anticancer agents express their cytotoxicity via induction of apoptosis in the target cells. This article summarize the recent studies on apoptosis in view of its molecular mechanism and the relation to diseases.
Hashimoto
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Sasaki Institute.
D017209:Apoptosis / Q000502:physiology*; D006801:Humans