[Cell cycle clock and its dysregulation in bronchopulmonary cancers].
The cell cycle is the process in which two daughter cells are produced with a strictly identical genetic makeup to the mother cell. Several genes are implicated in activating (oncogenes) or inhibiting (tumor suppressor genes) the cycle. Abnormal gene function can contribute to development of cancer. We describe here the normal cell cycle, its regulation and dysregulation in bronchogenic cancer.
Brechot
J M
JM
Service de Pneumologie, Hôtel-Dieu, Paris.
D001683:Biological Clocks; D002453:Cell Cycle; D018797:Cell Cycle Proteins / Q000502:physiology; D002471:Cell Transformation, Neoplastic; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*
D018797:Cell Cycle Proteins