title: Hypereosinophilic syndrome or chronic eosinophilic leukemia: report of a case with a lytic bone lesion.
abstract: Some cases of hypereosinophilic syndrome and myeloproliferative disorders exhibit common features and thus pose diagnostic and therapeutic problems. We describe a 68-year-old patient who presented with such features and developed lytic lesion in the tibia. Based on our case and a review of literature we suggest that cases like ours should be classified and treated as chronic eosinophilic leukemia (a myeloproliferative disorder) rather than as a hypereosinophilic syndrome or as an atypical chronic myeloid leukemia.
authors.affiliation: Department of Pathology, Peter MacCallum Cancer Institute, East Melbourne, Victoria, Australia.
authors.forename: S
authors.initials: S
authors.lastname: Juneja
authors.forename: J
authors.initials: J
authors.lastname: Stewart
authors.forename: A
authors.initials: A
authors.lastname: McKenzie
authors.forename: D
authors.initials: D
authors.lastname: Venter
authors.forename: H
authors.initials: H
authors.lastname: Januszewicz
mesh_terms: D000368:Aged; D001847:Bone Diseases / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000145:classification / Q000473:pathology*; D007951:Leukemia, Myeloid / Q000145:classification / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D009196:Myeloproliferative Disorders / Q000145:classification / Q000473:pathology*; D013977:Tibia / Q000473:pathology