[The characteristics of the peripheral blood monocytes in diabetics].
The study was aimed at laboratory evaluation of monocytes in peripheral blood of patients with insulin-dependent and non-insulin-dependent diabetes mellitus. Irrespective of the disease type and clinical features, monocytes count at the expense of Fc-positive monocytes was increased, activity of monocytes in the test NBT reduction was inhibited. The problem of monocyte involvement in diabetic angiopathy genesis and the role of insulin in this process are discussed. The findings justify introduction of immunomodulating therapy of diabetes mellitus patients with drugs acting on monocytes.
Galenok
V A
VA
Zhuk
E A
EA
D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002908:Chronic Disease; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D003925:Diabetic Angiopathies / Q000097:blood / Q000209:etiology; D006801:Humans; D016130:Immunophenotyping; D007958:Leukocyte Count; D008875:Middle Aged; D009000:Monocytes / Q000276:immunology / Q000378:metabolism*; D011961:Receptors, Fc / Q000097:blood
D011961:Receptors, Fc