title: Toxoplasmosis in pregnancy: research on 2295 women in Rome and its province.
abstract: The authors report the data concerning 2295 women tested for toxoplasmosis immunodiagnosis, in the Department of Infectious and Tropical Diseases of "La Sapienza" University of Rome in the years 1993-1994. Four hundred eleven cases (17.9%) were positive for IgG only; 2 cases (0.1%) for IgM only; 15 cases (0.6%) for both IgG and IgM while 1867 cases (81.4%) were negative. 1668 women were pregnant. In this group 260 (15.6%) were positive for IgG only, 2 (0.1%) for IgM only, and 10 (10.6%) for both IgG and IgM; in one case there was a spontaneous absorption in the 10th week of pregnancy, in another case a still-birth in the 20th week with brain lesions; a child was born with phocomelia of the right arm and one with a clubfoot. While it is possible to explain the absorption and the still-birth with the toxoplasma infection, it is difficult to understand the causes of the abnormality of the limbs.
authors.affiliation: Department of Infectious and Tropical Diseases, La Sapienza University, Rome, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Leone
authors.forename: B
authors.initials: B
authors.lastname: Allori
authors.forename: A
authors.initials: A
authors.lastname: Antognoli
authors.forename: S
authors.initials: S
authors.lastname: Catania
authors.forename: B
authors.initials: B
authors.lastname: Cerri
authors.forename: S
authors.initials: S
authors.lastname: Cicalini
authors.forename: C M
authors.initials: CM
authors.lastname: Lanzalone
authors.forename: A S
authors.initials: AS
authors.lastname: Miglietta
authors.forename: F
authors.initials: F
authors.lastname: Rossi
authors.forename: I
authors.initials: I
authors.lastname: Ilardi
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis / Q000276:immunology; D007075:Immunoglobulin M / Q000032:analysis / Q000276:immunology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology; D012384:Rome / Q000453:epidemiology; D014123:Toxoplasmosis / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M