title: Results of directional coronary atherectomy in Northern New England. Northern New England Cardiovascular Disease Study Group.
abstract: The role of directional coronary atherectomy (DCA) in interventional cardiology remains uncertain. We report the Northern New England regional experience with DCA from 1991 to 1994. Data were collected on 11,178 patients having had an intervention on a single lesion in a single vessel (798 DCAs; 10,380 percutaneous transluminal angioplasties [PTCA]). The use of DCA increased from 1.8% of interventions in 1991 to 10% in 1994. Compared with PTCA, DCA patients were younger, more often men, had more 1-vessel disease and more coronary artery bypass surgery (CABG). DCA was more often used in the left anterior descending artery, in vein grafts, for restenoses, for subtotal occlusions, and with type A lesions. Angiographic success (96.7%) and clinical success (93%) were good. Adverse events were rare: mortality 0.9%, emergent CABG 2.2%, nonfatal myocardial infarction 2.8%. After adjusting for case-mix, there was no difference between DCA and PTCA for in-hospital mortality (odds ratio [OR] = 1.03, 95% confidence interval [CI] 0.44 to 2.43, p = 0.95) or need for emergent CABG (OR = 1.27, 95% CI 0.77 to 2.10, p = 0.34). Atherectomy patients were more likely to have a nonfatal myocardial infarction (OR = 2.0, 95% CI 1.26 to 3.20, p <0.01), to sustain an injury to the femoral or brachial artery (OR = 2.89, 95% CI 1.52 to 5.51, p <0.01), and to have a clinically successful procedure (OR = 1.37, 95% CI 1.01 to 1.88, p = 0.05). Our results support the relative safety and effectiveness of DCA as its use disseminated into the region.
authors.affiliation: Department of Cardiology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA.
authors.forename: D J
authors.initials: DJ
authors.lastname: O'Rourke
authors.forename: D J
authors.initials: DJ
authors.lastname: Malenka
authors.forename: J F
authors.initials: JF
authors.lastname: Robb
authors.forename: W A
authors.initials: WA
authors.lastname: Bradley
authors.forename: M A
authors.initials: MA
authors.lastname: Kellett
authors.forename: S
authors.initials: S
authors.lastname: Shubrooks
authors.forename: M
authors.initials: M
authors.lastname: Hearne
authors.forename: P
authors.initials: P
authors.lastname: Verlee
authors.forename: D
authors.initials: D
authors.lastname: Wennberg
authors.forename: P T
authors.initials: PT
authors.lastname: Vaitkus
authors.forename: J
authors.initials: J
authors.lastname: O'Meara
authors.forename: T J
authors.initials: TJ
authors.lastname: Ryan
authors.forename: B
authors.initials: B
authors.lastname: Hettleman
authors.forename: M
authors.initials: M
authors.lastname: Miller
authors.forename: H
authors.initials: H
authors.lastname: Quinton
authors.forename: A
authors.initials: A
authors.lastname: Sengupta
authors.forename: G T
authors.initials: GT
authors.lastname: O'Connor
mesh_terms: D000368:Aged; D017225:Atherectomy, Coronary; D015986:Confounding Factors, Epidemiologic; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000401:mortality / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009511:New England; D016017:Odds Ratio; D012306:Risk; D016019:Survival Analysis; D016896:Treatment Outcome