title: Nutritional regulation of insulin-like growth factor-I mRNA expression in barramundi, Lates calcarifer.
abstract: The effect of nutritional status on IGF-I mRNA expression in the liver and brain of juvenile barramundi (Lates calcarifer) was investigated. Fish were either fed a satiety ration (SAT) or starved (STV) for 6 weeks. Starved fish demonstrated significantly lower condition factor and hepatic IGF-I mRNA expression at 3 and 6 weeks, when compared with the SAT group. IGF-I mRNA expression in the brain was 10 fold lower than the liver and was not affected by ration size. These results suggest the liver is the major site of IGF-I mRNA synthesis and hepatic but not brain IGF-I mRNA expression is regulated by food availability in juvenile barramundi.
authors.affiliation: Department of Zoology and Tropical Ecology (Division of Aquaculture), James Cook University of North Queensland, Townsville, Australia.
authors.forename: S J
authors.initials: SJ
authors.lastname: Matthews
authors.forename: A K
authors.initials: AK
authors.lastname: Kinhult
authors.forename: P
authors.initials: P
authors.lastname: Hoeben
authors.forename: V R
authors.initials: VR
authors.lastname: Sara
authors.forename: T A
authors.initials: TA
authors.lastname: Anderson
mesh_terms: D000818:Animals; D001492:Bass / Q000235:genetics* / Q000254:growth & development; D001921:Brain / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental; D007334:Insulin-Like Growth Factor I / Q000235:genetics*; D008099:Liver / Q000378:metabolism; D009752:Nutritional Status; D012333:RNA, Messenger / Q000235:genetics* / Q000378:metabolism*; D013217:Starvation / Q000235:genetics; D014018:Tissue Distribution
chemical_list: D012333:RNA, Messenger; D007334:Insulin-Like Growth Factor I