[The effect of the combined use of mineral water and rutin on the function of the adrenal cortex and pancreatic islet apparatus (an experimental study)].
Before modelling of experimental ulcer according to I. S. Zavodskaia the animals (157 male Wistar rats) were given for 24 days mineral water Essentuki N 17 and rutin in a dose 20 or 40 mg. Those given 20 mg of rutin in combination with mineral water demonstrated a higher rise in blood concentrations of hydrocortisone, insulin and thyroxine. Gastric mucosa and levels of serum alpha-1, alpha-2, beta-globulins and albumins were less damaged.
Polushina
N D
ND
Kozhevnikov
S A
SA
Makarov
V A
VA
Vergeĭchik
E N
EN
Kartazaeva
V A
VA
Liubchik
V E
VE
D000302:Adrenal Cortex / Q000187:drug effects* / Q000503:physiopathology; D000818:Animals; D003131:Combined Modality Therapy; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D004353:Drug Evaluation, Preclinical; D006294:Health Resorts; D007515:Islets of Langerhans / Q000187:drug effects* / Q000503:physiopathology; D008297:Male; D008900:Mineral Waters / Q000008:administration & dosage; D051381:Rats; D017208:Rats, Wistar; D012426:Russia; D012431:Rutin / Q000008:administration & dosage / Q000494:pharmacology*; D013276:Stomach Ulcer / Q000097:blood / Q000188:drug therapy
D008900:Mineral Waters; D012431:Rutin