[Predictive factors of local recurrence of in situ intraductal carcinoma. Apropos of 217 cases].
The authors have reviewed 217 cases of pure intraductal carcinomas with a mean follow-up of 98 months (with 2 deaths out of 31 recurrences from which 35% into adenocarcinomas). The data concerning the diagnosis, the tumor size, the pathological type, the surgical treatment, more of less associated to radiation therapy are detailed. The aim of this work was to give a more reliable way or approaching the recurrence rate (31/217) to be able to apply a more conservative treatment to these cases. The lymph node dissection and removal seams to be useless in the in situ carcinomas. Concerning the tumor size, the local tumors can be treated by conservative surgical procedures and do not get any benefit from radiotherapy. The opposite is true concerning more largely invasive tumor. Concerning the histology, the non-comedocarcinomatous tumors get less benefit from radiotherapy than the comedocarcinomatous type. The study of the tumor limits and the reliquats seem to be useful. The treatment chosen and applied remains the major prognostic element in the probability of recurrence.
Abbes
M
M
Centre Antoine-Lacassagne, Service de chirurgie cancérologique et réparatrice, Nice, France.
Lange
A C
AC
Daoudi
K
K
Lallement
M
M
D000206:Actuarial Analysis; D000328:Adult; D000368:Aged; D001365:Axilla / Q000601:surgery; D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D002278:Carcinoma in Situ / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D018270:Carcinoma, Ductal, Breast / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008408:Mastectomy / Q000379:methods; D008875:Middle Aged; D015999:Multivariate Analysis; D009364:Neoplasm Recurrence, Local; D011237:Predictive Value of Tests; D011379:Prognosis; D016896:Treatment Outcome