title: Active nuclear transport of chicken lipovitellin-2.
abstract: Chicken lipovitellin-2 is a small, approximately 30 kDa yolk protein, derived from the intracellular breakdown of the precursor protein vitellogenin. In principle, lipovitellin-2 is small enough to directly diffuse into the nucleus. Our results, however, demonstrate that its nuclear transport is an active process which can be inhibited by wheat germ agglutinin, chilling, and energy depletion. The N-terminal sequence analysis identifies chicken lipovitellin-2 beginning at Ala1544 in the C-terminal region of vitellogenin yielding of protein of 30,982 Da.
authors.affiliation: Department of Biochemistry and Biotechnology, University of Kuopio, Finland.
authors.forename: Z
authors.initials: Z
authors.lastname: Luo
authors.lastname: Annikka-Linnala-Kankkunen
authors.forename: A
authors.initials: A
authors.lastname: Itkonen
authors.forename: P H
authors.initials: PH
authors.lastname: Mäenpää
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001693:Biological Transport, Active; D002460:Cell Line; D002467:Cell Nucleus / Q000378:metabolism*; D002645:Chickens; D002522:Chlorocebus aethiops; D003593:Cytoplasm / Q000378:metabolism; D015387:Egg Proteins, Dietary / Q000378:metabolism*; D008969:Molecular Sequence Data
chemical_list: D015387:Egg Proteins, Dietary; C106338:lipovitellin 2