Synaptic transmission: well-placed modulators.
Metabotropic glutamate receptors are involved in the modulation of synaptic transmission; their localization in perisynaptic areas would appear to limit their activation by endogenous glutamate, but recent reports suggest that this strategic placement allows use-dependent activation of these synaptic modulators.
Forsythe
I D
ID
Department of Cell Physiology and Pharmacology, Faculty of Medicine, University of Leicester, Maurice Shock Medical Sciences Building, University Road, PO Box 138, Leicester, LE1 9HN, UK.
Barnes-Davies
M
M
D002451:Cell Compartmentation; D018698:Glutamic Acid / Q000378:metabolism*; D008959:Models, Neurological; D009473:Neuronal Plasticity; D018091:Receptors, AMPA / Q000502:physiology; D018094:Receptors, Metabotropic Glutamate / Q000502:physiology*; D016194:Receptors, N-Methyl-D-Aspartate / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology*
D018091:Receptors, AMPA; D018094:Receptors, Metabotropic Glutamate; D016194:Receptors, N-Methyl-D-Aspartate; D018698:Glutamic Acid