[Disposition toward mood genes].
Genetic factors together with psychological heredity have been involved in the genesis of mood disorders for a long time. Beside chromosomes X and 11, many other tracks exist. Results are heterogeneous and likely because of clinical, etiopathogenic and genetic heterogeneity of these diseases. Studies multiplicity strengthen the determinism complexity of the mood disorders. Since positive results published remain poorly replicated they receive from readers a reception as variable as the mood changes of the illnesses they concern. However, these studies lead to a better definition of their limits. Either clinical, biological or genetic, these limits would be on the decline and human genetic applied to psychiatry might improve etiopathogenic and therapeutic knowledges of mood disorders.
Guedj
F
F
Université Paris V et Service hospitalo-universitaire de Santé mentale et de Thérapeutique.
D001714:Bipolar Disorder / Q000235:genetics*; D002880:Chromosomes, Human, Pair 11; D003866:Depressive Disorder / Q000235:genetics*; D008040:Genetic Linkage / Q000235:genetics; D005838:Genotype; D006801:Humans; D012307:Risk Factors; D012729:Sex Chromosome Aberrations / Q000235:genetics; D014960:X Chromosome