Immunity status against poliomyelitis in persons 13-14 years old living in Rome.
The immunity against poliomyelitis in 1000 subjects 13-14 years old was evaluated. Neutralizing antibodies against poliovirus type 1, 2 and 3 were detected in 97.6%, 95.8% and 70% of samples, respectively. 3/1000 (0.3%) subjects were simultaneously seronegative to the three types. WHO does not suggest a protective level of International Units (IU), but our data indicate that such level is 0.45 IU for polio type 1, 0.65 IU for the type 2 and 0.138 for the type 3. A booster dose of vaccine in adolescence to ensure personal and herd immunity is recommended.
Mastroeni
I
I
Department of Experimental Biology, University of Cagliari, Italy.
Patti
A M
AM
Fabrizi
A
A
Santi
A L
AL
Manduca
A M
AM
Vescia
N
N
Squarcione
S
S
Fara
G M
GM
D000293:Adolescent; D000914:Antibodies, Viral / Q000097:blood*; D006801:Humans; D007117:Immunization, Secondary; D011051:Poliomyelitis / Q000276:immunology* / Q000517:prevention & control; D017955:Poliovirus / Q000276:immunology*; D012384:Rome
D000914:Antibodies, Viral