[Study of the phagocytic ability of blood polymorphonuclear leukocytes from rabbits and guinea pigs upon administering Ebola virus].
Study of the phagocytic activity of polymorphonuclear leukocytes (PMNL) of rabbits resistant to Ebola virus and guinea pigs susceptible to it, repeatedly challenged with live or inactivated Ebola virus in accordance with the immunization protocols, showed a much higher phagocytic activity in animals resistant to the virus than in those susceptible to it. Such behavior of PMNL in guinea pigs may be explained by the absence of the necessary cytokine background activating the neutrophils.
Dadaveva
A A
AA
Sizikova
L P
LP
Bakulina
L F
LF
Chepurnov
A A
AA
D000818:Animals; D004198:Disease Susceptibility / Q000276:immunology; D029043:Ebolavirus / Q000276:immunology*; D006168:Guinea Pigs; D009504:Neutrophils / Q000276:immunology*; D010587:Phagocytosis; D011817:Rabbits; D014765:Viral Vaccines / Q000008:administration & dosage
D014765:Viral Vaccines