Eosinophil-colony stimulating activity in blister fluid of bullous pemphigoid.
We examined eosinophil-colony stimulating activity in blister fluid or serum obtained from patients with bullous pemphigoid using the methylcellulose semi-solid hematopoietic stem cell culture system, and demonstrated that the blister fluid of patients with bullous pemphigoid generated strong eosinophil-colony stimulating activity. This evidence suggests that eosinophil-colony stimulating activity in blister fluid probably influences the induction of eosinophilia in bullous pemphigoid.
Kawachi
Y
Y
Department of Dermatology, University of Tsukuba, Ibaraki, Japan.
Otsuka
F
F
D000368:Aged; D000369:Aged, 80 and over; D001768:Blister / Q000378:metabolism*; D001790:Blood Physiological Phenomena; D001826:Body Fluids / Q000378:metabolism* / Q000502:physiology; D002478:Cells, Cultured; D003115:Colony-Stimulating Factors / Q000378:metabolism*; D017077:Culture Media, Conditioned / Q000494:pharmacology; D004804:Eosinophils / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010391:Pemphigoid, Bullous / Q000097:blood / Q000378:metabolism*; D013234:Stem Cells / Q000187:drug effects / Q000502:physiology
D003115:Colony-Stimulating Factors; D017077:Culture Media, Conditioned