title: [Effect of Fe2+ ions on the hemolysis induced by products of psoralen photo-oxidation].
abstract: The effects of Fe2+ ions on haemolysis induced by previously photooxidized psoralen (POP-haemolysis) were investigated. It was shown that POP-haemolysis was strongly activated by Fe2+ ions when ferrous ions were added to erythrocytes just after addition of POP. If POP was preincubated with Fe2+ before mixing with erythrocytes, then POP completely lost its ability to induce haemolysis. These data indicate the peroxidic nature of POP products responsible for haemolysis.
authors.forename: N N
authors.initials: NN
authors.lastname: Zhuravel'
authors.forename: I V
authors.initials: IV
authors.lastname: Belichenko
authors.forename: A A
authors.initials: AA
authors.lastname: Kiagova
authors.forename: E P
authors.initials: EP
authors.lastname: Lysenko
authors.forename: E M
authors.initials: EM
authors.lastname: Khalilov
authors.forename: A Ia
authors.initials: AIa
authors.lastname: Potapenko
mesh_terms: D005296:Ferrous Compounds / Q000494:pharmacology*; D011564:Furocoumarins / Q000737:chemistry / Q000494:pharmacology*; D006461:Hemolysis / Q000187:drug effects*; D006801:Humans; D066298:In Vitro Techniques; D010084:Oxidation-Reduction; D017319:Photosensitizing Agents / Q000494:pharmacology*
chemical_list: D005296:Ferrous Compounds; D011564:Furocoumarins; D017319:Photosensitizing Agents