title: The AP2 domain of APETALA2 defines a large new family of DNA binding proteins in Arabidopsis.
abstract: APETALA2 (AP2) plays an important role in the control of Arabidopsis flower and seed development and encodes a putative transcription factor that is distinguished by a novel DNA binding motif referred to as the AP2 domain. In this study we show that the AP2 domain containing or RAP2 (related to AP2) family of proteins is encoded by a minimum of 12 genes in Arabidopsis. The RAP2 genes encode two classes of proteins, AP2-like and EREBP-like, that are defined by the number of AP2 domains in each polypeptide as well as by two sequence motifs referred to as the YRG and RAYD elements that are located within each AP2 domain. RAP2 genes are differentially expressed in flower, leaf, inflorescence stem, and root. Moreover, the expression of at least three RAP2 genes in vegetative tissues are controlled by AP2. Thus, unlike other floral homeotic genes, AP2 is active during both reproductive and vegetative development.
authors.affiliation: Department of Biology, Sinsheimer Laboratories, University of California, Santa Cruz, CA 95064, USA.
authors.forename: J K
authors.initials: JK
authors.lastname: Okamuro
authors.forename: B
authors.initials: B
authors.lastname: Caster
authors.forename: R
authors.initials: R
authors.lastname: Villarroel
authors.forename: M
authors.initials: M
authors.lastname: Van Montagu
authors.forename: K D
authors.initials: KD
authors.lastname: Jofuku
mesh_terms: D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000235:genetics*; D029681:Arabidopsis Proteins; D001483:Base Sequence; D015870:Gene Expression; D017343:Genes, Plant; D018398:Homeodomain Proteins / Q000235:genetics*; D008969:Molecular Sequence Data; D005810:Multigene Family; D009687:Nuclear Proteins / Q000235:genetics*; D010940:Plant Proteins / Q000235:genetics*; D017433:Protein Structure, Secondary
chemical_list: C499534:APETALA2 protein, Arabidopsis; D029681:Arabidopsis Proteins; D018398:Homeodomain Proteins; D009687:Nuclear Proteins; D010940:Plant Proteins