Microtubule dynamics: treadmilling comes around again.
Although it is generally believed that microtubules have minus ends bound to the centrosome and free plus ends that exhibit dynamic instability, recent observations show that the minus ends can be free and that modulation of dynamic instability at both ends can result in treadmilling and flux in interphase cells.
Waterman-Storer
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Department of Biology, CB# 3280, 607 Fordham Hall, University of North Carolina, Chapel Hill, North Carolina 27599, USA. waterman@email.unc.edu
Salmon
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D007399:Interphase / Q000502:physiology*; D008869:Microtubule-Associated Proteins / Q000378:metabolism; D008870:Microtubules / Q000502:physiology*; D008954:Models, Biological; D009068:Movement / Q000502:physiology
D008869:Microtubule-Associated Proteins