Eicosapentaenoic acid and docosahexaenoic acid inhibit DNA synthesis through inhibiting cdk2 kinase in vascular smooth muscle cells.
Terano
T
T
Second Department of Internal Medicine, Chiba University School of Medicine, Japan.
Shiina
T
T
Yamamoto
K
K
Ban
T
T
Hirai
A
A
Tamura
Y
Y
Saito
Y
Y
Kitagawa
M
M
D000818:Animals; D016203:CDC2 Protein Kinase / Q000037:antagonists & inhibitors*; D002478:Cells, Cultured; D004261:DNA Replication / Q000187:drug effects*; D004281:Docosahexaenoic Acids / Q000494:pharmacology*; D015118:Eicosapentaenoic Acid / Q000494:pharmacology*; D009131:Muscle, Smooth, Vascular / Q000378:metabolism*; D051381:Rats; D011921:Rats, Inbred WKY; D015398:Signal Transduction / Q000187:drug effects*
D004281:Docosahexaenoic Acids; D015118:Eicosapentaenoic Acid; D016203:CDC2 Protein Kinase