V3 peptide enzyme immunoassay for serotyping HIV-1 infected pregnant Thais.
Previous molecular epidemiological studies show that at least 2 subtypes of HIV-1 circulate in Thailand. HIV-1 subtype B or Thai genotype B was associated with an early epidemic and was prevalent in intravenous drug users. Meanwhile, HIV-1 subtype E or Thai genotype A was becoming widespread among heterosexuals. We studied the HIV subtypes of 161 HIV-1 seropositive pregnant women. Of these, 143 pregnant patients (88.8%) tested positive for subtype E alone and 8 women (5.0%) had evidence of infection with subtype B alone. There was serologic evidence of infection with a mixture of subtypes in 7 women while the infecting subtype could not be identified in the remaining 3 women. This result agrees with previous information that subtype E predominates in Thai heterosexuals.
Taechowisan
T
T
Department of Biology, Faculty of Science, Silpakorn University, Nakorn Pathom, Thailand.
Sutthent
R
R
Louisirirotchanakul
S
S
Puthavathana
P
P
Wasi
C
C
D005260:Female; D015699:HIV Envelope Protein gp120 / Q000032:analysis*; D015658:HIV Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D015497:HIV-1 / Q000145:classification* / Q000276:immunology; D006801:Humans; D007124:Immunoenzyme Techniques; D010446:Peptide Fragments / Q000032:analysis*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology; D012703:Serotyping; D013785:Thailand / Q000453:epidemiology
D015699:HIV Envelope Protein gp120; C059762:HIV envelope protein gp120 (305-321); D010446:Peptide Fragments