title: Neurohumoral control of ionic pumping in molluscan muscle: III. Cholinergic control of the response to low potassium levels.
abstract: 1. Isolated radular protractor muscles (RPM) of Busycon canaliculatum show a complex response to potassium-free solution. 2. While exposed to a bathing solution lacking K+, the RPM begins to respond with a hyperpolarizing phase. Within minutes, this gives way to a depolarizing phase (DP). After readmission of a bathing solution containing K+, there is an extra hyperpolarizing phase. 3. Acetylcholine over a range of concentrations from 10(-8)M to 10(-3)M progressively enhances the DP. 4. The action of acetylcholine is sodium dependent.
authors.affiliation: Department of Zoology, University of Rhode Island, Kingston 02881, USA.
authors.forename: R B
authors.initials: RB
authors.lastname: Hill
mesh_terms: D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D008564:Membrane Potentials / Q000502:physiology; D008974:Mollusca / Q000502:physiology*; D009132:Muscles / Q000187:drug effects / Q000502:physiology; D011188:Potassium / Q000502:physiology; D012964:Sodium / Q000502:physiology
chemical_list: D012964:Sodium; D000109:Acetylcholine; D011188:Potassium