Evidence for the polyp-cancer sequence in gallbladder cancer.
We report a patient with symptomatic biliary disease and who was diagnosed by ultrasound to have a large polypoid gallbladder lesion. Histopathology revealed adenoma in combination with carcinoma in situ. The evidence for the adenoma-carcinoma sequence in gallbladder cancer and diagnostic and therapeutic implications are discussed.
Harbison
J
J
Department of Surgery, St. Vincent's Hospital, Dublin.
Reynolds
J V
JV
Sheahan
K
K
Gibney
R G
RG
Hyland
J M
JM
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology*; D018256:Adenomatous Polyps / Q000000981:diagnostic imaging / Q000473:pathology*; D000328:Adult; D002278:Carcinoma in Situ / Q000000981:diagnostic imaging / Q000473:pathology*; D005704:Gallbladder / Q000473:pathology; D005706:Gallbladder Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008297:Male; D014463:Ultrasonography