A case of eosinophilic pneumonia and vasculitis induced by diflunisal.
Drug-induced pneumonitis is an uncommon complication of nonsteroidal anti-inflammatory drug administration. Herein is the first reported case of pneumonitis resulting from diflunisal therapy. The patient demonstrated clinical and biopsy evidence of systemic vasculitis. She responded dramatically to administration of systemic glucocorticoids.
Rich
M W
MW
Department of Internal Medicine, Summa Health System, Akron, Ohio 44304, USA.
Thomas
R A
RA
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D004061:Diflunisal / Q000009:adverse effects*; D005260:Female; D006801:Humans; D011657:Pulmonary Eosinophilia / Q000139:chemically induced* / Q000175:diagnosis; D014657:Vasculitis / Q000139:chemically induced* / Q000175:diagnosis
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004061:Diflunisal