title: Identification of the ahp operon of Salmonella typhimurium as a macrophage-induced locus.
abstract: Previously, we tagged a macrophage-induced Salmonella typhimurium locus with Mudlux (K. P. Francis and M. P. Gallagher, Infect. Immun. 61:640-649, 1993). The insertion lies within the OxyR-regulated ahpC locus and conveys alkyl peroxide sensitivity. Plasmid-encoded ahp reverses sensitivity but reduces luminescence. This suggests that OxyR is titrated by the multicopy ahp promoter.
authors.affiliation: Division of Biology, University of Edinburgh, Scotland.
authors.forename: K P
authors.initials: KP
authors.lastname: Francis
authors.forename: P D
authors.initials: PD
authors.lastname: Taylor
authors.forename: C J
authors.initials: CJ
authors.lastname: Inchley
authors.forename: M P
authors.initials: MP
authors.lastname: Gallagher
mesh_terms: D002874:Chromosome Mapping; D004268:DNA-Binding Proteins; D006861:Hydrogen Peroxide / Q000494:pharmacology; D008264:Macrophages / Q000502:physiology*; D009876:Operon; D010088:Oxidoreductases / Q000235:genetics*; D010544:Peroxidases; D054464:Peroxiredoxins; D012097:Repressor Proteins / Q000235:genetics; D012486:Salmonella typhimurium / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics
chemical_list: D004268:DNA-Binding Proteins; D012097:Repressor Proteins; D014157:Transcription Factors; D006861:Hydrogen Peroxide; D010088:Oxidoreductases; D010544:Peroxidases; D054464:Peroxiredoxins