Endocrine carcinoma of the kidney.
A 4-cm mass in the right kidney of a 43-year-old female had an endocrine appearance by light microscopy and electron microscopy confirmed this impression, demonstrating the presence of numerous cytoplasmic granules of endocrine caliber. Unusual features were patchy immunoreactivity for chromogranin, and polarity of the granules within the neoplastic cells. Extrarenal extension and liver metastasis were documented.
Gurley
S D
SD
Department of Pathology, University of Texas M. D. Anderson Cancer Center, Houston 77030, USA.
Luna
M A
MA
Ordonez
N G
NG
Mackay
B
B
D000328:Adult; D001707:Biopsy, Needle; D002276:Carcinoid Tumor / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D002864:Chromogranins / Q000032:analysis; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007633:Keratins / Q000032:analysis; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008854:Microscopy, Electron; D014057:Tomography, X-Ray Computed
D002864:Chromogranins; D007633:Keratins