title: Intracranial metastatic adenocarcinoma of the prostate presenting as visual disturbance.
abstract: We report two cases of intracranial metastatic adenocarcinoma of the prostate that presented with visual disturbance. The two patients had no prior history of prostate cancer and both underwent invasive neurosurgical procedures. Progressive neurological decline mandated craniotomy in one patient and the other patient underwent transphenoidal surgery for biopsy. Androgen deprivation therapy was instituted postoperatively for both patients when prostate cancer was determined to be the source of the metastatic lesions.
authors.affiliation: Department of Surgery, Walter Reed Army Medical Center, Washington, D.C., USA.
authors.forename: D M
authors.initials: DM
authors.lastname: Preston
authors.forename: S M
authors.initials: SM
authors.lastname: Zeidman
authors.forename: M
authors.initials: M
authors.lastname: Spevak
authors.forename: J W
authors.initials: JW
authors.lastname: Moul
authors.forename: R A
authors.initials: RA
authors.lastname: Costabile
mesh_terms: D000010:Abducens Nerve; D000230:Adenocarcinoma / Q000473:pathology / Q000556:secondary*; D000368:Aged; D001859:Bone Neoplasms / Q000556:secondary; D001932:Brain Neoplasms / Q000556:secondary*; D003390:Cranial Nerve Neoplasms / Q000556:secondary; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000209:etiology; D010243:Paralysis / Q000209:etiology; D011471:Prostatic Neoplasms / Q000473:pathology*; D014786:Vision Disorders / Q000209:etiology*