title: Pathogenesis of non-traumatic atlanto-axial subluxation (Grisel's syndrome).
abstract: Non-traumatic atlanto-axial subluxation (AAS) is an uncommon complication of upper neck inflammatory processes and head and neck surgery. It is also known under the eponym of Grisel's syndrome (GS). We present a case report of a 6-year-old boy with GS that resulted from a retropharyngeal abscess. A diagnosis was not made until 2 months after the occurrence of infection. Re-evaluation of repeated CT scans of the neck showed the sequential development of AAS. These findings implied that the pathogenesis of GS is a distention of the ligaments between the atlas and axis rather than loosening of the ligaments caused by the spread of an inflammatory edema from the soft tissues of the neck as has been proposed by others.
authors.affiliation: Department of Otolaryngology, Länssjukhuset Ryhov, Jönköping, Sweden.
authors.forename: N R
authors.initials: NR
authors.lastname: Welinder
authors.forename: P
authors.initials: P
authors.lastname: Hoffmann
authors.forename: S
authors.initials: S
authors.lastname: Håkansson
mesh_terms: D001268:Atlanto-Axial Joint / Q000000981:diagnostic imaging; D002648:Child; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D004204:Joint Dislocations / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D008297:Male; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D017703:Retropharyngeal Abscess / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D014057:Tomography, X-Ray Computed; D014103:Torticollis / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy