title: [Contrast media in MR mammography].
abstract: A standardized relationship between concentration of contrast media and normalized signal intensity should be the basis of a diagnostic evaluation of MR-mammography at different sites and with different sequences. In this work we compared the dynamic range of the MR-compatible contrast medium Magnevist at different sequences and machines. For this purpose we made measurements with a phantom, consisting of MR-compatible glass tubes filled with contrast medium of different concentrations. The glass tubes were placed in a water bath. All measurements were made with breast coils. The signal intensity of the glass tubes was normalized to the signal intensity of the native probe (water = 1). These normalized dynamic curves were compared with each other in order to find, for the different machines, the sequence which is nearest to a defined "Standard-Curve". As this task proved not possible for all machines, we measured how the dynamic curves of the different machines related to the "Standard-Curve". For all sequences we made also measurements with a female student to assure the quality of the pictures. Thus the participating radiologists can now compare their dynamic measurements of breast lesions with each other.
authors.affiliation: Zentrum Mamma-Diagnostik und Therapie, Freiburg, Saar.
authors.forename: P
authors.initials: P
authors.lastname: Tontsch
authors.forename: M
authors.initials: M
authors.lastname: Bauer
authors.forename: G
authors.initials: G
authors.lastname: Birmelin
authors.forename: E
authors.initials: E
authors.lastname: von Landenberg
authors.forename: T B
authors.initials: TB
authors.lastname: Moeller
authors.forename: G
authors.initials: G
authors.lastname: Raible
mesh_terms: D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000175:diagnosis*; D003287:Contrast Media; D004867:Equipment Design; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives*; D019047:Phantoms, Imaging; D012015:Reference Standards
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D019786:Gadolinium DTPA