title: Adverse drug reaction to rifampin: a case with long lasting antiplatelet antibodies.
abstract: Rifampin is a drug able to induce adverse reactions involving both the kidney and the hematological system. We observed a case, throughly studied and we deemed worth-while to report it, for some important features that were evident. Transient hemolytic anemia, recoverable acute renal failure, persistent increased titer of anti-platelet antibody lasting also after 3 weeks from the withdrawal of the drug and in spite of corticosteroid therapy, could be explained by the immune mechanisms that are, therefore, postulated.
authors.affiliation: Istituto di Medicina Interna e Geriatria, Universitä Cattolica del Sacro Cuore, Roma, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Tricerri
authors.forename: M
authors.initials: M
authors.lastname: Vangeli
authors.forename: C
authors.initials: C
authors.lastname: Addario
authors.forename: L
authors.initials: L
authors.lastname: Guidi
authors.forename: C
authors.initials: C
authors.lastname: Bartoloni
authors.forename: S
authors.initials: S
authors.lastname: Magalini
authors.forename: N
authors.initials: N
authors.lastname: Gentiloni Silveri
mesh_terms: D000368:Aged; D000743:Anemia, Hemolytic / Q000139:chemically induced; D000904:Antibiotics, Antitubercular / Q000009:adverse effects*; D001323:Autoantibodies / Q000097:blood*; D001792:Blood Platelets / Q000276:immunology*; D006801:Humans; D008297:Male; D012293:Rifampin / Q000009:adverse effects*; D013921:Thrombocytopenia / Q000139:chemically induced
chemical_list: D000904:Antibiotics, Antitubercular; D001323:Autoantibodies; D012293:Rifampin