title: Evaluation of a policy of total mesorectal excision for rectal and rectosigmoid cancers.
abstract: BACKGROUND
  Total mesorectal excision (TME) is advocated for rectal cancer but the indications and extent of resection vary widely between surgeons.
  
  
  METHODS
  Seventy-six consecutive patients (61 elective, 15 acute admission) with rectal or rectosigmoid cancer were admitted to a unit where TME was the preferred surgical option for potentially curative cancer at all levels of the rectum.
  
  
  RESULTS
  Procedures undertaken were anterior resection (38 patients), abdominoperineal resection (18), Hartmann's procedure (ten) and transanal excision (one). Six patients had proximal faecal diversion alone and surgery was withheld in three. Anastomotic leaks occurred in six of 37 patients who had anterior resection with primary anastomosis, resulting in one early death. The presence of a proximal stoma did not influence the rate or seriousness of anastomotic dehiscence. After potentially curative TME in 45 patients, there have been eight local recurrences, four associated with systemic metastases and four which occurred in isolation (median follow-up 34 months).
  
  
  CONCLUSIONS
  Curative TME was deemed appropriate in 59 per cent of unselected patients with rectal cancer. It was associated with few local recurrences but a morbidity rate that questions its role in treatment of upper third tumours.
authors.affiliation: Department of General Surgery, Queen Elizabeth Hospital, Gateshead, UK.
authors.forename: P J
authors.initials: PJ
authors.lastname: Hainsworth
authors.forename: M J
authors.initials: MJ
authors.lastname: Egan
authors.forename: W J
authors.initials: WJ
authors.lastname: Cunliffe
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical; D003107:Colorectal Surgery / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011182:Postoperative Care; D012004:Rectal Neoplasms / Q000503:physiopathology / Q000601:surgery*; D012811:Sigmoid Neoplasms / Q000503:physiopathology / Q000601:surgery*; D015996:Survival Rate; D016896:Treatment Outcome