[The immunomorphological changes in the duodenal mucosa in peptic ulcer].
Results of immunomorphological investigation of the duodenal tissue, taken for biopsy at the time of operative intervention for the duodenal ulcer in 23 patients, are presented. Lowering of IgA-synthesizing cells count in lamina propria of the duodenal mucosa was determined. Deposition of IgG and the C3 component in vessels, the enlargement of IgA-synthesizing cells confirms the presence of antigenic properties of affected duodenum and the participation of immunocomplex and autoimmune mechanisms in pathogenesis of the duodenal ulcer disease.
Kuzovkova
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D003176:Complement C3 / Q000378:metabolism; D004381:Duodenal Ulcer / Q000276:immunology* / Q000473:pathology*; D004386:Duodenum / Q000276:immunology* / Q000473:pathology*; D005455:Fluorescent Antibody Technique; D006801:Humans; D007111:Immunity, Cellular; D007136:Immunoglobulins / Q000378:metabolism; D007413:Intestinal Mucosa / Q000276:immunology* / Q000473:pathology*
D003176:Complement C3; D007136:Immunoglobulins