title: Childhood hypophosphatasia. A case report.
abstract: Hypophosphatasia is a hereditary disease that can present as premature exfoliation of deciduous dentition in young children. We present a case of a 32-month-old female with a history of skeletal problems who spontaneously exfoliated three mandibular primary teeth. It was the premature exfoliation of her mandibular teeth that led to the diagnosis of childhood hypophosphatasia.
authors.affiliation: Department of Dentistry and Pathology, Mount Sinai Medical Center, New York, USA.
authors.forename: M
authors.initials: M
authors.lastname: Ramer
authors.forename: R
authors.initials: R
authors.lastname: Basta
authors.forename: K
authors.initials: K
authors.lastname: Fisher
mesh_terms: D002675:Child, Preschool; D003481:Cuspid; D003739:Dental Cementum / Q000002:abnormalities; D003786:Dental Pulp Cavity / Q000002:abnormalities; D005260:Female; D006801:Humans; D007014:Hypophosphatasia / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D007180:Incisor; D008334:Mandible; D014080:Tooth Exfoliation / Q000209:etiology*; D014094:Tooth, Deciduous