Kinetics of trans- and cis-resveratrol (3,4',5-trihydroxystilbene) after red wine oral administration in rats.
Kinetics of trans- and cis-resveratrol (3,4',5-trihydroxystilbene), a natural compound from grape products, have been evaluated in rats after oral administration of red wine. Resveratrol concentrations were measured in plasma, heart, liver and kidneys. Tissue concentrations showed a significant cardiac bioavailability and strong affinity for liver and kidneys.
Bertelli
A A
AA
Institute of Anatomy, University of Milan, Italy.
Giovannini
L
L
Stradi
R
R
Urien
S
S
Tillement
J P
JP
Bertelli
A
A
D000284:Administration, Oral; D000818:Animals; D001682:Biological Availability; D007668:Kidney / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008297:Male; D009206:Myocardium / Q000378:metabolism; D012372:ROC Curve; D051381:Rats; D017208:Rats, Wistar; D000077185:Resveratrol; D013267:Stilbenes / Q000097:blood / Q000493:pharmacokinetics*; D014018:Tissue Distribution; D014920:Wine
D013267:Stilbenes; D000077185:Resveratrol