Helicobacter pylori-associated gastroduodenal disease in childhood.
Helicobacter pylori is responsible for one of the most frequently encountered infectious diseases worldwide. Infection due to H pylori can lead to the development of gastritis and peptic ulcer disease. The presence of H pylori in the human stomach also represents an increased risk for gastric cancer and gastric lymphoma. Recent epidemiologic data obtained in adults suggest that the actual colonization with H pylori is in fact determined by childhood factors. Therefore, the pediatric age group represents the ideal target population for studies concerning the pathogenesis and epidemiology of H pylori infection. This review addresses the spectrum of H pylori-associated gastroduodenal disease in childhood.
Blecker
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Division of Pediatric Gastroenterology, Louisiana State University Medical Center, New Orleans 70112, USA.
D000328:Adult; D000367:Age Factors; D001327:Autoimmune Diseases / Q000382:microbiology; D002648:Child; D004378:Duodenal Diseases / Q000175:diagnosis / Q000382:microbiology*; D004381:Duodenal Ulcer / Q000175:diagnosis / Q000382:microbiology; D005260:Female; D005756:Gastritis / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori; D006801:Humans; D008223:Lymphoma / Q000209:etiology / Q000382:microbiology; D018442:Lymphoma, B-Cell, Marginal Zone / Q000209:etiology / Q000382:microbiology; D008228:Lymphoma, Non-Hodgkin / Q000209:etiology / Q000382:microbiology; D008297:Male; D010437:Peptic Ulcer / Q000175:diagnosis / Q000382:microbiology; D012307:Risk Factors; D013272:Stomach Diseases / Q000175:diagnosis / Q000382:microbiology*; D013274:Stomach Neoplasms / Q000209:etiology / Q000382:microbiology; D013276:Stomach Ulcer / Q000175:diagnosis / Q000382:microbiology