title: Molecular semantics and the origin of life.
abstract: The physical origin of life addresses itself to a semantic process on material grounds, in which causation toward contextualization is at work. Physically semantic process of whatever kind is specific in that every material participant is searching and modifying the material context to be fitted in. Fundamental to the physical semantics is the process of measurement proceeding internally among the constituent material participants, whereas the molecular syntax alone as embodied in the form of the quantum-mechanical equation of motion supplemented independently by exogenous boundary conditions cannot cope with the material process underlying the origin. A basic physical attribute of the phenomenon called life is variable duration, in contrast to invariant duration of Galilean inertia. In fact, moleculars replication thought as a harbinger of the phenomenon of life is a concrete form of variable duration and could be established unless internal measurement being instrumental to physically semantic process is forcibly eliminated by some external means. Physical experiments on the onset of molecular replication could become feasible only when external controllability over the intended experiments even at nano-meter scales is abandoned so as to save the room of internal measurement on the part of participating molecules.
authors.affiliation: Department of BioEngineering, Nagaoka University of Technology, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Matsuno
mesh_terms: D005075:Biological Evolution; D004261:DNA Replication; D046911:Macromolecular Substances; D008954:Models, Biological; D000069497:Origin of Life; D012660:Semantics; D013816:Thermodynamics
chemical_list: D046911:Macromolecular Substances