Multiple myeloma with hairy cell-like features.
Hairy cell leukemia (HCL) and multiple myeloma (MM) are well-described disease entities with characteristic clinical and pathologic features. We describe two patients initially treated for MM in whom atypical clinical and morphologic features subsequently developed that raised the possibility of HCL. Although the cytologic appearance and immunophenotype were not diagnostic of HCL, these cases challenge the criteria used to diagnose MM, HCL, and other recently described villous neoplasms.
Algino
K M
KM
Department of Pathology, The University of Texas Health Science Center at San Antonio, 78284, USA.
Hendrix
L E
LE
Henderson
C A
CA
Banks
P M
PM
Craig
F E
FE
D001853:Bone Marrow / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D016130:Immunophenotyping; D007943:Leukemia, Hairy Cell / Q000473:pathology*; D008214:Lymphocytes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000175:diagnosis*