title: The effect of chairside relining materials on rat palatal mucosa.
abstract: OBJECTIVE
  To investigate the effects of denture relining materials on oral mucosa in vivo in a rat model.
  
  
  METHODS
  Denture-like appliances covering the palate in Wistar rats were relined with a resilient soft linting material and a hard 'chairside' relining material. The effects on the palatal epithelium were studied by quantitative analysis using computerized planimetry.
  
  
  RESULTS
  The relining materials caused an increase in the thickness of the keratinized layer, while not increasing the total epithelial thickness.
  
  
  CONCLUSIONS
  Relining materials are not totally without effect on oral mucosa. Further in vivo research is indicated.
authors.affiliation: Department of Prosthodontics, Glasgow Dental Hospital and School NHS Trust, UK.
authors.forename: S C
authors.initials: SC
authors.lastname: Barclay
authors.forename: D G
authors.initials: DG
authors.lastname: MacDonald
authors.forename: I B
authors.initials: IB
authors.lastname: Watson
mesh_terms: D000180:Acrylic Resins / Q000494:pharmacology*; D000818:Animals; D001485:Basement Membrane / Q000187:drug effects / Q000473:pathology; D003819:Denture Bases; D003822:Denture Liners; D003823:Denture Rebasing; D004195:Disease Models, Animal; D004548:Elasticity; D004848:Epithelium / Q000187:drug effects / Q000473:pathology; D007633:Keratins; D008297:Male; D008689:Methacrylates / Q000494:pharmacology; D008768:Methylmethacrylates / Q000494:pharmacology; D009061:Mouth Mucosa / Q000187:drug effects* / Q000473:pathology; D010159:Palate / Q000187:drug effects* / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar; D013499:Surface Properties
chemical_list: D000180:Acrylic Resins; D008689:Methacrylates; D008768:Methylmethacrylates; C103363:kooliner; C069457:Coe-Soft denture lining material; D007633:Keratins; C009931:poly(ethylmethacrylate)