Nuclear pleomorphism in typical carcinoid tumours of the lung: problems in frozen section interpretation.
Pulmonary typical carcinoid tumours are generally easy to diagnose with their uniform cells, carcinoid growth pattern and lack of mitoses. However, nuclear pleomorphism, which is common in other neuroendocrine tumours, is not emphasized in pulmonary carcinoid tumours. Three cases of typical carcinoid tumours, because of marked nuclear pleomorphism on frozen section, were misdiagnosed as non-small cell carcinomas.
Sheppard
M N
MN
Department of Histopathology, Royal Brompton Hospital, London, UK.
D000328:Adult; D002276:Carcinoid Tumor / Q000473:pathology*; D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology; D003951:Diagnostic Errors; D005629:Frozen Sections; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008875:Middle Aged