Acute myelogenous leukaemia in a mare.
A 5-year-old Thoroughbred mare presented with a 4 week history of weight loss, fever and leukopenia. Rectally, a large active foetus, thickened spleen and an abdominal mass were palpated. Leukopenia, mild anaemia, marked thrombocytopenia and hyperfibrinogenaemia were found. Cytology and cytochemical staining of a bone marrow aspirate supported a diagnosis of acute myelogenous leukaemia. The mare deteriorated despite medical therapy and was humanely euthanased.
Ringger
N C
NC
Department of Large Animal Clinical Sciences, University of Florida, Gainesville 32610, USA.
Edens
L
L
Bain
P
P
Raskin
R E
RE
Larock
R
R
D000818:Animals; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D005260:Female; D006734:Horse Diseases / Q000175:diagnosis / Q000188:drug therapy; D006736:Horses; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D011241:Prednisone / Q000627:therapeutic use; D011379:Prognosis; D016896:Treatment Outcome
D018931:Antineoplastic Agents, Hormonal; D011241:Prednisone