[The Göttinger minipig as an animal model in hip endoprosthesis. Anatomy, anesthesia, operation results].
The Göttingen mini swine is a good experimental animal. The electrolytes and the bone healing rate is comparable to human. The weight of the animals should be 30-45 kg. All surgery is performed under endotracheal general anaesthesia without any complication. There is minimal blood loss because blood pressure is only 40/80 mmHg. We used the anterolateral approach. The feature peculiarity of this animal model are: 1. Skin incision should start 10 cm cranial to the tail and should be curved. 2. The osteotomy of the head is V-shaped in maximal external rotation. 3. The acetabulum is prepared with a 23.5 mm reamer. 4. The stem should be implanted first. After completion of the preliminary test operations, 10 animals were operated in the described standard manner. During one year follow-up there was only one radiological cup-loosening.
Thomsen
M
M
Stiftung Orthopädische Univ.-Klinik, Heidelberg.
von Strachwitz
B
B
Loew
M
M
Cotta
H
H
Kirsch
S
S
Schunk
O
O
Kubein-Meesenburg
D
D
D000077:Acetabulum / Q000601:surgery; D000717:Anatomy, Comparative; D000818:Animals; D004195:Disease Models, Animal; D005270:Femur Head / Q000601:surgery; D006621:Hip Joint / Q000033:anatomy & histology; D006622:Hip Prosthesis / Q000379:methods*; D006801:Humans; D010027:Osteotomy / Q000379:methods; D011183:Postoperative Complications; D013552:Swine; D013556:Swine, Miniature