title: [Effect of green tea (matcha) on gastrointestinal tract absorption of polychlorinated biphenyls, polychlorinated dibenzofurans and polychlorinated dibenzo-p-dioxins in rats].
abstract: This paper presents the liver distribution and fecal excretion of polychlorinated biphenyls (PCB), polychlorinated dibenzofurans (PCDF) congeners and polychlorinated dibenzo-p-dioxins (PCDD) congeners, in male rats fed with powdered green tea (matcha). The rats were given a treatment diet containing 10% matcha for the first five days. Then, the animals were administered 4 g of 10% matcha diet containing 0.5 ml of the casual rice-bran oil of Yusho that had occurred in the Southwest part of Japan in 1968 and kept on the same diet for another five days. The fecal excretion of PCB, PCDF and PCDD in the group fed with 10% matcha were 4.4, 2.4-9.1 and 2.5-4.7 times higher (p < 0.01), respectively, than that in the control group. The liver distribution of PCB, PCDF and PCDD in the same groups were 79%, 20-75% and 26-67% of the control group, respectively. These findings suggest that administration of matcha is useful as a treatment of Yusho patients exposed to PCB, PCDF and PCDD.
authors.affiliation: Fukuoka Institute of Health and Environmental Sciences, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Morita
authors.forename: T
authors.initials: T
authors.lastname: Matsueda
authors.forename: T
authors.initials: T
authors.lastname: Iida
mesh_terms: D000818:Animals; D001572:Benzofurans / Q000378:metabolism*; D000072338:Dibenzofurans, Polychlorinated; D005753:Gastric Mucosa / Q000378:metabolism; D007408:Intestinal Absorption / Q000187:drug effects*; D008099:Liver / Q000378:metabolism; D008297:Male; D011078:Polychlorinated Biphenyls / Q000378:metabolism*; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D013662:Tea
chemical_list: D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D000072317:Polychlorinated Dibenzodioxins; D013662:Tea; D011078:Polychlorinated Biphenyls