title: Management of abdominal aortic prosthetic graft infection requiring emergent treatment.
abstract: The purpose of this study was to investigate mortality and morbidity rates and long-term outcome of patients who underwent emergency treatment of abdominal aortic prosthetic graft infection. Between January 1984 and December 1993, 18 men aged fifty-nine +/- sixteen years were operated on as an emergency for an acute life-threatening complication of aortic prosthetic graft infection. The grafts had been implanted for abdominal aortic aneurysm in 9 patients and aortoiliac occlusive disease in 9, from one to one hundred seventy months previously. Five (28%) patients presented with a hemorrhagic shock due to a fistula between the vascular reconstruction and the small bowel (4 patients) or the right ureter (1 patient) and 13 (72%) had generalized sepsis. The grafts were always radically explanted. Extraanatomic revascularization procedures included 6 axillopopliteal and 12 axillofemoral bypass grafts. Operative mortality was 39% (7 patients), and 3 (9%) limbs were amputated within thirty days. Two (11%) patients died after seven and twelve months, respectively, of septic complications, and 1 (5%) patient died after six months from an unrelated cause. Eight (73%) patients are still alive at a mean follow-up of fifty +/- thirty-four months, but in 3 the extraanatomic bypass was removed for infection and 5 major amputations were performed. Two-year survival and limb salvage rates were 44% and 50%, respectively. Aortic prosthetic graft infections that require emergent treatment continue to demonstrate high early and late mortality and limb loss rates despite aggressive intervention and limb salvage procedures. Newer methods of managing these complications should continue to be investigated.
authors.affiliation: 1st Department of Surgery, La Sapienza University, Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Mingoli
authors.forename: P
authors.initials: P
authors.lastname: Sapienza
authors.forename: L
authors.initials: L
authors.lastname: di Marzo
authors.forename: G
authors.initials: G
authors.lastname: Sgarzini
authors.forename: C
authors.initials: C
authors.lastname: Burchi
authors.forename: C
authors.initials: C
authors.lastname: Modini
authors.forename: A
authors.initials: A
authors.lastname: Cavallaro
mesh_terms: D000671:Amputation, Surgical; D001012:Aorta, Abdominal / Q000601:surgery*; D017544:Aortic Aneurysm, Abdominal / Q000601:surgery; D001018:Aortic Diseases / Q000209:etiology / Q000601:surgery; D001157:Arterial Occlusive Diseases / Q000601:surgery; D001366:Axillary Artery / Q000601:surgery; D001807:Blood Vessel Prosthesis / Q000009:adverse effects*; D002423:Cause of Death; D004630:Emergencies; D005263:Femoral Artery / Q000601:surgery; D005402:Fistula / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D007083:Iliac Artery; D007412:Intestinal Fistula / Q000209:etiology; D007421:Intestine, Small / Q000473:pathology; D007866:Leg / Q000098:blood supply / Q000601:surgery; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery / Q000601:surgery; D016459:Prosthesis-Related Infections / Q000209:etiology / Q000601:surgery*; D018805:Sepsis; D012771:Shock, Hemorrhagic / Q000209:etiology / Q000601:surgery; D015996:Survival Rate; D016896:Treatment Outcome; D014515:Ureteral Diseases / Q000209:etiology; D014548:Urinary Fistula / Q000209:etiology