title: [Intestinal stenosis during ulceronecrotizing enterocolitis].
abstract: BACKGROUND
  Intestinal stenosis following necrotizing enterocolitis (NE) occurred both in surgically-treated neonates after perforation, distal to an enterostomy and in medically-treated patients developing symptoms of obstruction. It has been proposed to detect stenosis by contrast enema before refeeding in those medically-treated patients. The aim of this study was to compare delay, clinical and pathological characteristics of surgical and medical patients, both after occlusion and prospective contrast studies.
  
  
  METHODS
  Fifteen patients out of 50 with NE observed from 1984 to 1994 developed one or several intestinal stenosis. Diagnosis of NE was based on usual clinical signs, X-ray pneumatosis (43 to 50) and/or perforation in 16 cases. Among these 16 surgical patients, 12 survived the initial perforation. Among the 34 medical patients, 11 were seen before 1989 and did not have contrast studies before refeeding; 23 seen after 1989 had a contrast enema before.
  
  
  RESULTS
  One or several stenosis occurred in four out of 12 surgical patients, four out of 11 medical patients without prospective contrast studies (one of them died from sepsis) and seven out of the 23 of the prospective group. On the whole, 26 stenosis occurred in 15 neonates: ten to the right colon, five to the transverse and 11 to the left colon. One ileal stenosis followed enterostomy. Delay of stenosis development was comparable in the three groups (between 3 weeks and 3 months). Pathologic examination showed similar lesions in the three groups (fibrosis 15, edema nine to 15 and chronic inflammation 12 to 15).
  
  
  CONCLUSIONS
  Among 46 neonates who survived the initial period, 15 developed stenosis, a 30% proportion similar in patients operated on for perforation or in medically-treated patients whose diagnosis was made after occlusion or after contrast enema as well. These results suggest that systematic stenosis detection by contrast enema may avoid complications and permit programmed one-stage surgery.
authors.affiliation: Centre de pédiatrie Edmond-Lesné, Hôpital d'enfants Armand-Trousseau, Paris, France.
authors.forename: J J
authors.initials: JJ
authors.lastname: Baudon
authors.forename: P
authors.initials: P
authors.lastname: Josset
authors.forename: G
authors.initials: G
authors.lastname: Audry
authors.forename: N
authors.initials: N
authors.lastname: Benlagha
authors.forename: O
authors.initials: O
authors.lastname: Fresco
mesh_terms: D003251:Constriction, Pathologic / Q000209:etiology; D004761:Enterocolitis, Pseudomembranous / Q000150:complications* / Q000628:therapy; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007410:Intestinal Diseases / Q000209:etiology* / Q000473:pathology; D008297:Male; D010538:Peritonitis / Q000150:complications; D012307:Risk Factors; D014456:Ulcer / Q000209:etiology / Q000628:therapy