title: Integrated system for preparation of bone cement and effects on cement quality and environment.
abstract: We developed a prepacked mixing system for the preparation of bone cement. The system is based on mixing and collection of bone cement under a vacuum and serves as both the storage and mixing device for the cement components, thereby minimizing the exposure of the operating staff to the monomer and the risk for contamination of the cement during preparation. We evaluated the system using Palacos R and Simplex P. The cement produced was compared with cement obtained from a commercially available mixing system. Temperature evolution during curing, handling characteristics, density, and porosity of the cement obtained were analyzed. The results showed that the experimental system produces cement with physical properties (i.e., setting times and temperature, porosity, and density) equal to or better than those obtained with commercially available systems. Reducing the amount of monomer in the experimental system led to a reduction of the curing temperature without compromising the physical properties of the cements.
authors.affiliation: Department of Orthopedics, Lund University Hospital, Sweden.
authors.forename: P
authors.initials: P
authors.lastname: Müller-Wille
authors.forename: J S
authors.initials: JS
authors.lastname: Wang
authors.forename: L
authors.initials: L
authors.lastname: Lidgren
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis* / Q000592:standards; D001843:Bone Cements / Q000138:chemical synthesis* / Q000592:standards; D004866:Equipment Contamination; D020366:Methylmethacrylate; D008768:Methylmethacrylates / Q000138:chemical synthesis* / Q000592:standards; D011786:Quality Control; D013696:Temperature; D013997:Time Factors
chemical_list: D001672:Biocompatible Materials; D001843:Bone Cements; D008768:Methylmethacrylates; D020366:Methylmethacrylate