[Lyell syndrome after amoxicillin administration in a 2 year old child].
The authors report a toxic epidermal necrolysis (TEN) due to ampicillin (Agram) in a 2-year-old child. During the acute phase a septic syndrome occurred. The severity of the clinical and biological symptoms led to the administration of antibiotics, their systematic use remaining controversial. Recovery was favourable in a paediatric burn centre. Sequelae were minor. TEN, the physiopathological mechanism of which remaining still unknown, may carry a vital risk.
Surbled
M
M
Service d'anesthésie-réanimation chirurgicale, Hôtel Dieu, Nantes, France.
Lejus
C
C
Milpied
B
B
Pannier
M
M
Souron
R
R
D000658:Amoxicillin / Q000009:adverse effects*; D000768:Anesthesia, General / Q000379:methods; D000818:Animals; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002675:Child, Preschool; D006224:Cricetinae; D006801:Humans; D015278:Intensive Care Units, Pediatric; D008297:Male; D013262:Stevens-Johnson Syndrome / Q000209:etiology* / Q000628:therapy
D000900:Anti-Bacterial Agents; D000658:Amoxicillin