Ribozymes: red in tooth and claw.
A population of catalytic RNA molecules has been engineered to operate and evolve in vitro in a continuous manner. The novel continuity of the process allows the propagation of many generations in a very short time and without the manual manipulation necessary with traditional in vitro selection techniques.
Robertson
M P
MP
Department of Chemistry, Indiana University, Bloomington, Indiana 47405, USA.
Ellington
A D
AD
D002384:Catalysis; D002474:Cell-Free System; D019143:Evolution, Molecular; D005818:Genetic Engineering; D000069497:Origin of Life; D016337:RNA, Catalytic / Q000235:genetics*
D016337:RNA, Catalytic