title: Endometrial carcinoma in a young patient with polycystic ovarian syndrome: first suspected at time of embryo transfer.
abstract: Adenocarcinoma of the endometrium is a rare condition in women under 40 years of age. However, patients with anovulatory polycystic ovarian syndrome are at risk of developing endometrial carcinoma due to the unopposed and prolonged effect of oestrogen on the endometrium. This case report discusses the dilemma of various treatment options for early disease in such patients.
authors.affiliation: Assisted Conception Unit, St James's University Hospital, Leeds, UK.
authors.forename: O
authors.initials: O
authors.lastname: Salha
authors.forename: P
authors.initials: P
authors.lastname: Martin-Hirsch
authors.forename: G
authors.initials: G
authors.lastname: Lane
authors.forename: V
authors.initials: V
authors.lastname: Sharma
mesh_terms: D000230:Adenocarcinoma / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D000328:Adult; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage / Q000627:therapeutic use; D004624:Embryo Transfer; D016889:Endometrial Neoplasms / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D005260:Female; D005307:Fertilization in Vitro; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy; D015907:Hysteroscopy; D017258:Medroxyprogesterone Acetate / Q000008:administration & dosage / Q000627:therapeutic use; D010062:Ovulation Induction; D011085:Polycystic Ovary Syndrome / Q000150:complications*
chemical_list: D018931:Antineoplastic Agents, Hormonal; D017258:Medroxyprogesterone Acetate