title: Limitation of dietary copper and zinc decreases superoxide dismutase activity in the onion fly, Delia antiqua.
abstract: Larvae of the onion fly, Delia antiqua, have lower superoxide dismutase (SOD) activity when they are fed a defined synthetic diet that contains no copper or zinc. SOD activity was rapidly recovered when these larvae were fed onion bulbs. Addition of copper and zinc to the synthetic diet also led to the recovery of SOD activity. Results of an immunoblotting analysis using anti-D. antiqua CuZnSOD mouse monoclonal antibody suggest that this alteration of SOD activity is dependent on the amount of CuZnSOD.
authors.affiliation: Laboratory of Applied Entomology, Faculty of Agriculture, University of Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Matsuo
authors.forename: S
authors.initials: S
authors.lastname: Ooe
authors.forename: Y
authors.initials: Y
authors.lastname: Ishikawa
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal; D003300:Copper / Q000008:administration & dosage*; D019327:Copper Sulfate / Q000494:pharmacology; D004032:Diet; D004175:Diptera / Q000201:enzymology* / Q000254:growth & development; D004790:Enzyme Induction / Q000187:drug effects; D007814:Larva / Q000201:enzymology / Q000254:growth & development; D051379:Mice; D013482:Superoxide Dismutase / Q000096:biosynthesis / Q000276:immunology / Q000378:metabolism*; D015032:Zinc / Q000008:administration & dosage*
chemical_list: D000911:Antibodies, Monoclonal; D003300:Copper; D013482:Superoxide Dismutase; D015032:Zinc; D019327:Copper Sulfate