Chondrosarcoma of the spine and thyroid carcinoma following radiation therapy for Hodgkin's lymphoma.
Second malignant neoplasms are an infrequent but well-documented sequelae of radiation therapy for childhood cancer. We report a 34-year-old man with chondrosarcoma of the spine and thyroid carcinoma diagnosed 24 years after radiation therapy for Hodgkin's lymphoma. Both tumors arose in the previously irradiated field and were not detected until the patient presented with paraplegia. The propensity of these neoplasms to arise in the previously irradiated field warrants physicians to be alert to any manifestations arising in this anatomic area.
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Department of Neurology, University of Mississippi Medical Center, Jackson 39216-4505, USA.
Fratkin
J
J
D000328:Adult; D002813:Chondrosarcoma / Q000000981:diagnostic imaging / Q000209:etiology*; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D009381:Neoplasms, Radiation-Induced / Q000000981:diagnostic imaging*; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging; D011859:Radiography; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging*; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging*