title: TcR zeta/CD3 signal transduction in T-cells: downstream signalling via ZAP-70, SLP-76 and FYB.
authors.affiliation: Division of Tumor Immunology, Dana-Farber Cancer Institute, Boston, MA, USA.
authors.forename: A J
authors.initials: AJ
authors.lastname: da Silva
authors.forename: M
authors.initials: M
authors.lastname: Raab
authors.forename: Z
authors.initials: Z
authors.lastname: Li
authors.forename: C E
authors.initials: CE
authors.lastname: Rudd
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D002352:Carrier Proteins / Q000096:biosynthesis / Q000502:physiology*; D002460:Cell Line; D003001:Cloning, Molecular; D006801:Humans; D007376:Interleukin-2 / Q000096:biosynthesis; D019169:Jurkat Cells; D008322:Mammals; D008565:Membrane Proteins / Q000276:immunology*; D010750:Phosphoproteins / Q000096:biosynthesis / Q000502:physiology*; D011505:Protein-Tyrosine Kinases / Q000096:biosynthesis / Q000502:physiology*; D011518:Proto-Oncogene Proteins; D051076:Proto-Oncogene Proteins c-fyn; D017260:Receptor-CD3 Complex, Antigen, T-Cell / Q000276:immunology*; D011948:Receptors, Antigen, T-Cell / Q000276:immunology*; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis; D015398:Signal Transduction; D018411:Spodoptera; D013601:T-Lymphocytes / Q000276:immunology* / Q000502:physiology; D014162:Transfection; D051746:ZAP-70 Protein-Tyrosine Kinase
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D002352:Carrier Proteins; C106957:FYB1 protein, human; D007376:Interleukin-2; D008565:Membrane Proteins; D010750:Phosphoproteins; D011518:Proto-Oncogene Proteins; D017260:Receptor-CD3 Complex, Antigen, T-Cell; D011948:Receptors, Antigen, T-Cell; D011993:Recombinant Fusion Proteins; C092947:SLP-76 signal Transducing adaptor proteins; C054979:antigen T cell receptor, zeta chain; D011505:Protein-Tyrosine Kinases; C494957:FYN protein, human; D051076:Proto-Oncogene Proteins c-fyn; D051746:ZAP-70 Protein-Tyrosine Kinase; C497261:ZAP70 protein, human