title: [Effectiveness of alcoholic hand disinfectants against methicillin resistant Staphylococcus aureus].
abstract: In order to determine the efficacy of hand disinfectants based on alcohol against three MRSA strains and 3 methicillin-susceptible S. aureus strains (MSSA), 1-propanol (60%) as well as Sterillium and Spitaderm were investigated in the quantitative suspension test at various dilutions and reactions times (15, 30 and 60s). All undiluted disinfectants revealed reduction factors > 6 against MRSA and MSSA after 30s. Diluted disinfectants (50%) were significantly less effective against MRSA at short reaction times (15 s) (p < 0.05). Sterillium in a dilution of 50% did not reach 5 reduction factors against either MRSA or MSSA after 30 s. The impact of an appropriate use of hand disinfectants in order to break chains of infections with MRSA is obvious.
authors.affiliation: Institut für Hygiene, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin.
authors.forename: G
authors.initials: G
authors.lastname: Kampf
authors.forename: R
authors.initials: R
authors.lastname: Jarosch
authors.forename: H
authors.initials: H
authors.lastname: Rüden
mesh_terms: D000433:1-Propanol / Q000494:pharmacology*; D015169:Colony Count, Microbial; D004202:Disinfectants / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004338:Drug Combinations; D006235:Hand Disinfection / Q000379:methods*; D006801:Humans; D016106:Methicillin Resistance; D008826:Microbial Sensitivity Tests; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D004202:Disinfectants; D004338:Drug Combinations; D000433:1-Propanol