Castleman's disease: a clinicopathologic study of 12 cases.
Castleman's disease observed in 12 Thai patients was investigated. The male to female ratio was 1:3. Peak prevalence was in the third and fourth decades. It is suggested that the disease in Orientals tends to have extrathoracic mass more often than in Caucasians. Solitary non-tender slow growing mass was the most common symptom. Generalized lymphadenopathy in association with cutaneous plasmocytoma was noted in one example while asymptmatic pelvic lesion in a patient was discovered incidentally. Histologically, the hyaline-vascular type was found in 8 instances, the remainders were plasma-cell type. Surgery was effective for localized lesions while systemic form could benefit from chemotherapy.
Kasantikul
V
V
Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Panyavoravut
V
V
Benjavongkulchai
S
S
Panichabhongse
V
V
D000293:Adolescent; D000328:Adult; D005871:Castleman Disease / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012744:Sex Ratio