High frequency oscillation and exogenous surfactant in the treatment of neonatal respiratory distress syndrome.
Surfactant therapy has become widely used in neonates suffering from respiratory distress syndrome. High frequency oscillation has been shown to be efficient and safe in animal models, but somewhat less convincing in human neonates. An overview is given of the experimental and clinical data assessing the combination of these two techniques. Personal preliminary data are briefly presented.
Claris
O
O
Department of Neonatology, Hôpital Edouard Herriot, Lyon, France.
Salle
B L
BL
D000818:Animals; D002986:Clinical Trials as Topic / Q000706:statistics & numerical data; D003131:Combined Modality Therapy / Q000592:standards; D004195:Disease Models, Animal; D006612:High-Frequency Ventilation / Q000592:standards*; D006801:Humans; D007231:Infant, Newborn; D011446:Prospective Studies; D012121:Respiration, Artificial / Q000379:methods / Q000592:standards; D012127:Respiratory Distress Syndrome, Newborn / Q000628:therapy*; D013501:Surface-Active Agents / Q000627:therapeutic use*; D016896:Treatment Outcome
D013501:Surface-Active Agents