title: Primary transplantation of allogeneic peripheral blood stem cell for severe aplastic anemia.
abstract: Primary allogeneic peripheral blood stem cell transplantation (allo-PBSCT) has not been previously described in the treatment of severe aplastic anemia (SAA). We report a patient with SAA who underwent primary allo-PBSCT with cells from her HLA-identical sibling and achieved rapid bone marrow reconstitution. The patient has been in complete remission with normal blood counts for 9 months following allo-PBSCT. This suggests that primary allo-PBSCT is a safe and effective alternative in the treatment of SAA.
authors.affiliation: Department of Medicine, Veterans General Hospital-Taipei, Taiwan, Republic of China.
authors.forename: H C
authors.initials: HC
authors.lastname: Hsu
authors.forename: W H
authors.initials: WH
authors.lastname: Tsai
authors.forename: J S
authors.initials: JS
authors.lastname: Lin
authors.forename: C H
authors.initials: CH
authors.lastname: Tzeng
authors.forename: S Y
authors.initials: SY
authors.lastname: Wang
authors.forename: C H
authors.initials: CH
authors.lastname: Ho
mesh_terms: D000293:Adolescent; D000741:Anemia, Aplastic / Q000628:therapy*; D016572:Cyclosporine / Q000627:therapeutic use; D005260:Female; D006086:Graft vs Host Disease / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007963:Leukocytes, Mononuclear / Q000166:cytology*; D033581:Stem Cell Transplantation; D014184:Transplantation, Homologous
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine