title: [Mast cells as a test of body state during electromagnetic exposure of varying intensity].
abstract: Effects of single and repeated exposure of mice, rats, and rabbits in magnetic fields at 50 Hz and 2 kA/m, 16 kA/m, and 32 kA/m on the populations of dermal, intestinal, and popliteal lymph node labrocytes were studied immediately and within one month after exposure. Single exposure in the magnetic fields of 2 kA/m and 16 kA/m for 4 hours did not produce any changes in labrocytes of these organs. Repeated exposure to 2 kA/m, 16 kA/m, and 32 kA/m for 4 hours during 5 days modulated the functional activity of labrocytes in all the organs. More extended (1.5-2 months) repeated exposure to the intensive magnetic field (32 kA/m) stimulated adaptation and regain of labrocyte populations in the dermal and popliteal lymph nodes whereas enhanced secretion, i.e. degranulation of labrocytes persisted in the intestine. Following one month after the 1.5-2-month exposure to 32 kA/m, labrocyte populations were recovered with the maximum effect in the lymph nodes. High magnetic sensitivity of labrocytes revealed in this study can be used as a test of body reactivity and adaptation to this physical agent. Differences in the reactivity of labrocytes of individual organs and species must be taken into account.
authors.forename: N A
authors.initials: NA
authors.lastname: Iurina
authors.forename: A I
authors.initials: AI
authors.lastname: Radostina
authors.forename: B M
authors.initials: BM
authors.lastname: Savin
authors.forename: V A
authors.initials: VA
authors.lastname: Remizova
authors.forename: I P
authors.initials: IP
authors.lastname: Kosova
mesh_terms: D000818:Animals; D015549:Basophil Degranulation Test; D004574:Electromagnetic Fields; D007422:Intestines / Q000166:cytology; D008198:Lymph Nodes / Q000166:cytology; D008407:Mast Cells / Q000528:radiation effects*; D051379:Mice; D008808:Mice, Inbred CBA; D011817:Rabbits; D051381:Rats; D012867:Skin / Q000166:cytology; D013997:Time Factors