title: [Disorders of central hemodynamics and phase structure of left ventricle systole in patients with veratrine poisoning].
abstract: Central hemodynamics, phase structure of left ventricular systole, and circulating blood volume were studied in 56 patients with acute poisoning with veratrine. Two main variants of hemodynamic disorders were distinguished. Exposure of up to 3-4 hours led to bradycardia with heart rate of up to 47/min but no appreciable hemo- or cardiodynamic disorders. A longer exposure resulted in a decrease of the circulating blood volume, development of the phase syndrome of myocardial hypodynamia with a drop of stroke volume and cardiac output and development of hypotonia. These results indicate the necessity of a differentiated approach to the treatment of circulatory disorders in patients poisoned with veratrine.
authors.forename: S R
authors.initials: SR
authors.lastname: Rokin
authors.forename: A V
authors.initials: AV
authors.lastname: Kustovskiĭ
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D006439:Hemodynamics; D006801:Humans; D008875:Middle Aged; D011041:Poisoning / Q000503:physiopathology; D013599:Systole; D016277:Ventricular Function, Left / Q000502:physiology; D014702:Veratrine / Q000506:poisoning*
chemical_list: D014702:Veratrine