Effects of serum from pregnant versus non-pregnant women on natural killer cell activity.
OBJECTIVE
To test the effect of serum obtained from in vitro fertilization-embryo transfer (IVF-ET) patients on the healthy volunteers natural killer (NK) cell activity.


METHODS
Retrospective non-randomized clinical study. Suppressive effect on NK cell activity was measured with serum obtained from 25 pregnant and 24 non-pregnant women during IVF-ET procedure.


RESULTS
Suppressive serum effect of volunteers' NK cell activity was significantly higher in pregnant than in non-pregnant women (P < 0.01).


CONCLUSIONS
The suppressive activity of serum from pregnant women on NK cell suppression activity was useful in predicting the establishment of a successful pregnancy.
Fujino
Y
Y
Department of Obstetrics and Gynecology, Osaka City University Medical School, Japan.
Nakamura
Y
Y
Ueda
K
K
Ozaki
K
K
Ito
F
F
Sun
T T
TT
Umesaki
N
N
Ogita
S
S
D000328:Adult; D015415:Biomarkers; D001769:Blood / Q000276:immunology*; D004624:Embryo Transfer; D005260:Female; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology*; D011247:Pregnancy / Q000097:blood*; D012189:Retrospective Studies
D015415:Biomarkers