Radiolabelled monoclonal antibodies in clinical and surgical oncology: a review.
Over the past decade, the role of immunoscintigraphy using radiolabelled monoclonal antibodies has been steadily growing in clinical oncology, and in particular, in radioimmunotherapy and radioimmunoguided surgery for the treatment of primary, recurrent, and metastatic colorectal, ovarian, gastric, and prostate cancer. Herein, the authors review the requirements for successful tumour radioimmunodetection and related procedures.
Biassoni
L
L
Department of Nuclear Medicine, St. Bartholomew's Hospital, London, UK.
D'Andrea
V
V
Biancari
F
F
Santoni
F
F
Dibra
A
A
De Antoni
E
E
D000911:Antibodies, Monoclonal / Q000627:therapeutic use; D006801:Humans; D007553:Isotope Labeling; D009369:Neoplasms / Q000000981:diagnostic imaging*; D016719:Radioimmunodetection
D000911:Antibodies, Monoclonal