title: Protac, a commercially available protein C activator from the venom of Agkistrodon contortrix contortrix, can activate factor V and factor VIII.
authors.affiliation: Department of Internal Medicine, Naval Medical Center, San Diego, USA.
authors.forename: P S
authors.initials: PS
authors.lastname: Gable
authors.forename: D T
authors.initials: DT
authors.lastname: Le
authors.forename: S I
authors.initials: SI
authors.lastname: Rapaport
mesh_terms: D017836:Agkistrodon; D000818:Animals; D001780:Blood Coagulation Tests / Q000379:methods; D003435:Crotalid Venoms; D004789:Enzyme Activation; D005165:Factor V / Q000378:metabolism*; D005169:Factor VIII / Q000378:metabolism*; D006801:Humans; D066298:In Vitro Techniques; D007202:Indicators and Reagents; D036341:Intercellular Signaling Peptides and Proteins; D010455:Peptides; D011486:Protein C / Q000032:analysis / Q000378:metabolism*; D011994:Recombinant Proteins / Q000378:metabolism
chemical_list: D003435:Crotalid Venoms; D007202:Indicators and Reagents; D036341:Intercellular Signaling Peptides and Proteins; D010455:Peptides; D011486:Protein C; D011994:Recombinant Proteins; C049647:snake venom protein C activator; D005165:Factor V; D005169:Factor VIII