title: Long-term results of radiofrequency catheter ablation in patients with Wolff-Parkinson-White syndrome.
abstract: BACKGROUND
  Information about the long-term results of radiofrequency catheter ablation, electrophysiologic characteristics of differently located accessory pathways, and the difference between a single accessory pathway and multiple accessory pathways was limited.
  
  
  METHODS
  Nine hundred and thirty-one patients with 1016 accessory pathways (APs) received electrophysiologic study and radiofrequency catheter ablation between July 1, 1989 and June 31, 1996. Group 1 included 856 (91.9%) patients with a single AP and Group 2 included 75 (8.1%) patients with multiple APs. The follow-up period was 48 +/- 37 months (range, 2 to 84 months).
  
  
  RESULTS
  Nine hundred and thirteen patients (98.1%) had successful ablation with a complication rate of 1.5%. In Group 1, left free wall pathways were ablated with fewer radiofrequency pulses, shorter procedure time, shorter radiation exposure time and a lower recurrence rate than those at other locations. Comparisons between Group 1 and Group 2 showed that the latter had higher incidences of antidromic tachycardia (3% vs 13%, p < 0.05) and atrial flutter/fibrillation (26% vs 37%, p < 0.05). Regarding radiofrequency catheter ablation, Group 2 needed more radiofrequency pulses (8.7 +/- 7.8 vs 5.5 +/- 7.7, p < 0.001), longer procedure time (3.3 +/- 1.4 vs 2.1 +/- 1.0 hours, p < 0.05) and radiation time (49 +/- 27 vs 29 +/- 19 minutes, p < 0.001), and a higher recurrence rate (10.6% vs 3.3%, p < 0.005) than those in Group 1. Thirty-six patients (4%) with recurrence had more right-side pathways than those without recurrence. In addition, difficult ablation (longer procedure time, longer radiation time and more radiofrequency pulses) was associated with a higher recurrence rate.
  
  
  CONCLUSIONS
  These findings demonstrated that a high success rate with a low recurrence and low complication rate of radiofrequency catheter ablation could be achieved in a large population with APs during a long follow-up period.
authors.affiliation: Department of Medicine, National Yang-Ming University School of Medicine, Taipei, Taiwan, R.O.C.
authors.forename: Y J
authors.initials: YJ
authors.lastname: Chen
authors.forename: S A
authors.initials: SA
authors.lastname: Chen
authors.forename: C T
authors.initials: CT
authors.lastname: Tai
authors.forename: C E
authors.initials: CE
authors.lastname: Chiang
authors.forename: S H
authors.initials: SH
authors.lastname: Lee
authors.forename: C W
authors.initials: CW
authors.lastname: Chiou
authors.forename: K C
authors.initials: KC
authors.lastname: Ueng
authors.forename: Z C
authors.initials: ZC
authors.lastname: Wen
authors.forename: W C
authors.initials: WC
authors.lastname: Yu
authors.forename: J L
authors.initials: JL
authors.lastname: Huang
authors.forename: A N
authors.initials: AN
authors.lastname: Feng
authors.forename: M S
authors.initials: MS
authors.lastname: Chang
mesh_terms: D000328:Adult; D017115:Catheter Ablation; D004594:Electrophysiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D013997:Time Factors; D016896:Treatment Outcome; D014927:Wolff-Parkinson-White Syndrome / Q000503:physiopathology / Q000601:surgery*