title: Diversion colitis: a cause of abdominal discomfort in spinal cord injury patients with colostomy.
abstract: Diversion colitis is thought to result from nutritional deficiencies secondary to fecal diversion. Symptoms include hemorrhagic purulent rectal discharge, abdominal pain, and tenesmus. 5-Aminosalicylic acid (5-ASA) and N-butyrate enemas have been reported to help this condition non-spinal cord injury (SCI) patients. We report the case of a 49-year-old C6 ASIA B tetraplegic man who had received colostomy because of intractable ileus 10 years earlier. He presented with a 2-week history of rectal pain and bleeding. Abdominal and rectal examination on admission were unremarkable. Colonoscopy showed a partial stricture 70cm proximally to the rectum. The colonic mucosa appeared granular and friable with evidence of linear ulceration. Histopathologic study was consistent with colitis. The patient developed fever, abdominal distention, and extensive retroperitoneal air after endoscopy, suggesting colonic perforation. He was treated with daily 5-ASA suppository and total parenteral nutrition for the presumed diagnosis of diversion colitis, and intravenous antibiotics for perforated colon. After 6 weeks of treatment with 5-ASA, the patient had decreased rectal pain and bleeding. This experience suggests that diversion colitis may be a cause of abdominal discomfort in SCI patients and that 5-ASA may be used in the management of diversion colitis.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, TX, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Lai
authors.forename: T Y
authors.initials: TY
authors.lastname: Chuang
authors.forename: G E
authors.initials: GE
authors.lastname: Francisco
authors.forename: J R
authors.initials: JR
authors.lastname: Strayer
mesh_terms: D015746:Abdominal Pain / Q000209:etiology*; D000636:Aminosalicylic Acids / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D003092:Colitis / Q000150:complications* / Q000188:drug therapy; D003125:Colostomy / Q000009:adverse effects*; D006801:Humans; D008297:Male; D019804:Mesalamine; D008875:Middle Aged; D013119:Spinal Cord Injuries
chemical_list: D000636:Aminosalicylic Acids; D000894:Anti-Inflammatory Agents, Non-Steroidal; D019804:Mesalamine