Loss of vision alone may result in seesaw nystagmus.
A patient is described who developed seesaw nystagmus (SSN) associated with progressive severe vision loss due to cone-rod dystrophy. She was otherwise neurologically normal, and findings on magnetic resonance imaging of the brain were normal, including optic chiasm, meso-diencephalic junction, and brainstem. The literature is reviewed on neurologically normal patients with SSN and ocular vision loss, and the hypothesis is presented that SSN may become manifest as a result of vision loss alone, even in patients with chiasmal lesions, without disruption of central ocular motility pathways.
May
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EF
Ophthalmology Service, Madigan Army Medical Center, Tacoma, Washington, USA.
Truxal
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AR
D000328:Adult; D004585:Electrooculography; D005133:Eye Movements; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009759:Nystagmus, Pathologic / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D010786:Photoreceptor Cells / Q000473:pathology; D012164:Retinal Diseases / Q000150:complications* / Q000175:diagnosis; D014786:Vision Disorders / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology