title: [Modification of the DNA spatial structure when complexed with cisplatin].
abstract: The experimental and theoretical analyses of the conformational transitions of DNA-cis-platinum complexes have been carried out. It is shown that at low concentrations of the ligand, the thermodynamic parameters of the helix-coil transition of the complexes are not the result of the local B-->A transition.
authors.affiliation: Florence University, Italy.
authors.forename: S G
authors.initials: SG
authors.lastname: Arutiunina
authors.forename: E Sh
authors.initials: ESh
authors.lastname: Mamasakhlisov
authors.forename: V F
authors.initials: VF
authors.lastname: Morozov
authors.forename: E B
authors.initials: EB
authors.lastname: Dalian
authors.forename: R E
authors.initials: RE
authors.lastname: Khachikian
authors.forename: P O
authors.initials: PO
authors.lastname: Vardevanian
authors.forename: P
authors.initials: P
authors.lastname: Orioli
authors.forename: B
authors.initials: B
authors.lastname: Bruni
mesh_terms: D000818:Animals; D002417:Cattle; D002945:Cisplatin / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D018736:DNA Adducts / Q000737:chemistry*; D008956:Models, Chemical; D009690:Nucleic Acid Conformation; D013816:Thermodynamics
chemical_list: D018736:DNA Adducts; C057270:cisplatin-DNA adduct; D004247:DNA; D002945:Cisplatin