title: Testosterone replacement therapy for male hypogonadism with a radiation-polymerized testicular prosthesis.
abstract: BACKGROUND
  The effect of an artificial testicular prosthesis on sexual disturbance in hypogonadal men was investigated.
  
  
  METHODS
  Twelve hypogonadal men were treated with testosterone replacement therapy delivered via radiation-polymerized testicular prostheses surgically implanted in their scrotums.
  
  
  RESULTS
  An average serum testosterone level of over 200 ng/dL was maintained for 48 months. Most patients treated with this prosthesis were satisfied with the improvement of their sexual activity. Moreover, the patients were psychologically more satisfied with the enlarged scrotum achieved with the implanted prosthesis.
  
  
  CONCLUSIONS
  We recommend this prosthesis as the first choice among testosterone-replacement therapies for hypogonadal men.
authors.affiliation: Department of Urology, Gunma University School of Medicine, Maebashi, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Imai
authors.forename: H
authors.initials: H
authors.lastname: Yamanaka
authors.forename: M
authors.initials: M
authors.lastname: Mashimo
authors.forename: M
authors.initials: M
authors.lastname: Asano
authors.forename: M
authors.initials: M
authors.lastname: Yoshida
mesh_terms: D000293:Adolescent; D000328:Adult; D001187:Artificial Organs; D004867:Equipment Design; D006801:Humans; D007006:Hypogonadism / Q000188:drug therapy* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011108:Polymers; D011183:Postoperative Complications; D019736:Prostheses and Implants; D011827:Radiation; D012611:Scrotum / Q000601:surgery; D013737:Testis; D013739:Testosterone / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D011108:Polymers; D013739:Testosterone