[HIV infection: future perspective for a so-called fatal disease?].
During the last 18 months, our knowledge and possibilities in the field of HIV infections have progressed in four principal domains: (1) better understanding of the dynamics of HIV infections and in particular of the importance of viral replication during the phase of latency, (2) possibility of measuring the viral charge and its use for diagnosis and to follow treatment, (3) access to very effective new anti-retroviral substances which permit hope of long-term stabilization of the infection, (4) clinical demonstration that combined treatments are superior to monotherapy. While, at the beginning of 1996, only three medications were commercialized, there were eight at the end of that year. This paper describes the implications for daily practice of recent scientific discoveries in the field of HIV infection. The importance of compliance is discussed, as well as that of clinical research.
von Overbeck
J
J
Département de médecine interne, Centre hospitalier universitaire vaudois, Lausanne.
Iten
A
A
D017088:AIDS-Related Opportunistic Infections / Q000517:prevention & control; D019380:Anti-HIV Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D018791:CD4 Lymphocyte Count; D004359:Drug Therapy, Combination; D015658:HIV Infections / Q000188:drug therapy* / Q000821:virology*; D006801:Humans; D010349:Patient Compliance; D010353:Patient Education as Topic; D012106:Research / Q000639:trends; D019562:Viral Load; D014779:Virus Replication
D019380:Anti-HIV Agents