title: Changes in evoked otoacoustic emissions in the guinea pig after pure-tone acoustic overstimulation.
abstract: To test if click-evoked otoacoustic emissions (CEOAEs) have frequency specificity, continuous changes in CEOAEs (especially frequency components of the CEOAE power spectrum) after pure-tone exposure in guinea pigs were examined. Pure-tone stimuli (0.5 kHz, 120 dB SPL; 2 kHz, 115 dB SPL; 4 kHz, 110 dB SPL) were given in a closed system for 3 min. After exposure, the frequency components in the CEOAE power spectrum decreased maximally at one-half octave or more above the overstimulation frequency. They partially recovered 2 h after exposure. The time course of compound action potential (CAP) thresholds after exposure was similar to that of the frequency components of the CEOAE power spectrum. It was concluded that some local damage caused by outer hair-cell dysfunction in the guinea pig cochlea can be detected by measuring shifts in frequency components in the CEOAE power spectrum.
authors.affiliation: Department of Otolaryngology, Nagoya University, School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Ueda
authors.forename: H
authors.initials: H
authors.lastname: Tsuge
authors.forename: T
authors.initials: T
authors.lastname: Hattori
mesh_terms: D000818:Animals; D001288:Attention / Q000502:physiology; D001305:Auditory Fatigue / Q000502:physiology; D006168:Guinea Pigs; D018072:Hair Cells, Auditory, Outer / Q000502:physiology; D008144:Loudness Perception / Q000502:physiology; D017084:Otoacoustic Emissions, Spontaneous / Q000502:physiology; D010775:Photic Stimulation; D010897:Pitch Discrimination / Q000502:physiology; D013018:Sound Spectrography