Pure silicate fragment in a recurrent stone former of calcium oxalate.
Long-time oral intake of magnesium-silicate-containing drugs is thought to be a causative factor inducing silicate urolithiasis. Besides, magnesium seems to play an anti-urolithogenic part in the formation of calcium oxalate stones. We report a recurrent calcium oxalate former who had been treated with magnesium aluminometasilicate antacid for gastric ulcer for approximately 17 years. One of the fragments found during extracorporeal shock wave lithotripsy was identified as 100% silicate. Deposition of silica was also found on other fragments. A large dose of magnesium (given in a part of the drug) might have little influence on the formation of calcium oxalate.
Ichiyanagi
O
O
Department of Urology, Yamagata University School of Medicine, Japan.
Nakada
T
T
Ishigooka
M
M
Hayami
S
S
Sanjo
Y
Y
Kubota
Y
Y
Nakashima
K
K
Sakai
H
H
Kuwahara
M
M
D017607:Aluminum Compounds / Q000627:therapeutic use*; D000863:Antacids / Q000627:therapeutic use*; D002129:Calcium Oxalate / Q000032:analysis*; D006801:Humans; D007669:Kidney Calculi / Q000737:chemistry* / Q000175:diagnosis / Q000628:therapy; D008096:Lithotripsy; D017616:Magnesium Compounds / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D017640:Silicates / Q000032:analysis* / Q000627:therapeutic use*; D013276:Stomach Ulcer / Q000188:drug therapy; D013997:Time Factors
D017607:Aluminum Compounds; D000863:Antacids; D017616:Magnesium Compounds; D017640:Silicates; D002129:Calcium Oxalate; C033065:aluminum magnesium silicate