title: Light chain deposition disease complicating familial Mediterranean fever.
abstract: Familial Mediterranean fever (fMf) is an inherited condition characterized by polyserositis and is sometimes complicated by AA renal amyloidosis leading to nephrotic syndrome and renal failure. We present a case of a man with fMf who presented with rapidly progressive renal failure caused by light chain deposition disease. This disease association has not previously been described in the medical literature.
authors.affiliation: Division of Nephrology, Beaumont Hospital, Dublin, Ireland.
authors.forename: J P
authors.initials: JP
authors.lastname: Vella
authors.forename: G D
authors.initials: GD
authors.lastname: Doyle
authors.forename: E
authors.initials: E
authors.lastname: Campbell
authors.forename: J J
authors.initials: JJ
authors.lastname: Walshe
mesh_terms: D000328:Adult; D018450:Disease Progression; D010505:Familial Mediterranean Fever / Q000150:complications* / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000378:metabolism*; D007674:Kidney Diseases / Q000150:complications* / Q000276:immunology / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D008297:Male
chemical_list: D007145:Immunoglobulin kappa-Chains