title: Wegener's presenting as submandibular swelling.
abstract: We describe a patient in whom bilateral swelling of submandibular glands was the initial manifestation of limited Wegener's disease. The diagnosis was based on positive anti-neutrophil cytoplasmic antibody [C-ANCA], dense inflammatory infiltrate predominantly of lymphocytes in submandibular glands, presence of non-caseating ill-formed granulomas in transbronchial biopsy and resolution of symptoms following immuno-suppressive treatment.
authors.affiliation: Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: S
authors.initials: S
authors.lastname: Singh
authors.forename: D
authors.initials: D
authors.lastname: Kaura
authors.forename: S
authors.initials: S
authors.lastname: Kumari
authors.forename: D
authors.initials: D
authors.lastname: Gupta
authors.forename: P
authors.initials: P
authors.lastname: Dey
authors.forename: S
authors.initials: S
authors.lastname: Suri
mesh_terms: D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis; D001706:Biopsy; D001999:Bronchoscopy; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012466:Salivary Gland Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D013363:Submandibular Gland / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic; D007166:Immunosuppressive Agents