[Redox properties of peptides potentially regulating animal hibernation].
Weak redox properties of peptides isolated from the brain of hibernating animals were determined in reactions with free radicals. The peptides Thr-Ser-Lys-Tyr-Arg (NKT) and Tyr-Arg diminished concentration of anion-radicals of dye excited by light, thus demonstrating electron-acceptor properties toward radicals. In contrast, the peptides Thr-Ser-Lys-Tyr (RZ-5) and Asp-Tyr acted as electron donors in the same radical reactions. The possible role of redox properties of these peptides in their regulation of Ca currents in excitable tissues is discussed.
Marinov
B S
BS
Ziganshin
R Kh
RKh
D000818:Animals; D001923:Brain Chemistry; D015220:Calcium Channels / Q000502:physiology; D006605:Hibernation / Q000502:physiology*; D010084:Oxidation-Reduction; D010455:Peptides / Q000737:chemistry / Q000302:isolation & purification*; D011898:Ranidae; D051381:Rats; D012589:Sciuridae
D015220:Calcium Channels; D010455:Peptides