Nongenetic variation, genetic-environmental interactions and altered gene expression. I. Temperature, photoperiod, diet, pH and sex-related effects.
The use of protein electrophoretic data for determining the relationships among species or populations is widespread and generally accepted. However, many confounding factors may alter the results of an electrophoretic study in such a way as to allow erroneous conclusions to be drawn in taxonomic, systematic or population studies. Such variables as temperature, photoperiod, salinity, pH and diet have been shown to influence enzymes and proteins both quantitatively and qualitatively. Production of distinct "cold" and "warm" isozymes or "seasonal" isozymes have been found in a variety of organisms. The factors that are or may be responsible for the appearance of these isozymes is discussed. Most studies that have demonstrated some apparent form of environmentally induced genetic expression have not determined that mechanisms responsible. However, proteolytic modification has been shown to produce seasonal isozymes of fructose 1,6-bisphosphatase in rabbit liver and may account for other seasonal isozymes. Acclimating organisms to various conditions may actually allow detection of cryptic genetic variation and provide valuable data. There are many aspects to consider in designing acclimation experiments, and the conditions used will vary according to the aim of the research. Polyploidy may contribute to the genesis of environmentally regulated isozymes. A review of this literature follows with additional hypotheses and conclusions. Recommendations are given for the resolution of real and potential problems.
Poly
W J
WJ
Department of Zoology, Southern Illinois University, Carbondale 62901-6501, USA. argulus5@siu.edu
D000064:Acclimatization / Q000235:genetics / Q000502:physiology; D000818:Animals; D004032:Diet; D004777:Environment; D015971:Gene Expression Regulation, Enzymologic / Q000235:genetics* / Q000502:physiology; D006863:Hydrogen-Ion Concentration; D017440:Photoperiod; D010944:Plants; D011506:Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D012737:Sex Factors; D013696:Temperature
D011506:Proteins