title: Nesidioblastosis in the adult surgical management.
abstract: Nesidioblastosis is an exceedingly rare occurrence in the adult and, when it appears, it is usually part of a MEA1 syndrome. We present a case of nesidioblastosis in a young woman, with no concurrent endocrine pathology, while we discuss in detail the diagnostic and therapeutic problems posed by this condition. The selected treatment was sub-total pancreatectomy (70-80%) and the histopathologic and immunohistochemical tests of the surgical specimen showed: "Diffuse Nesidioblastosis". The histopathologic and immuno-histochemical features of the resected pancreas are analysed in detail.
authors.affiliation: St. Martha's Hospital-General Surgery, Histopathology Ward, Lisboa, Portugal.
authors.forename: J P
authors.initials: JP
authors.lastname: Garcia
authors.forename: T
authors.initials: T
authors.lastname: França
authors.forename: C
authors.initials: C
authors.lastname: Pedroso
authors.forename: C
authors.initials: C
authors.lastname: Cardoso
authors.forename: M O
authors.initials: MO
authors.lastname: Cid
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007515:Islets of Langerhans / Q000378:metabolism / Q000473:pathology*; D010180:Pancreatectomy / Q000379:methods*; D010182:Pancreatic Diseases / Q000378:metabolism / Q000473:pathology / Q000601:surgery*