[Digitonin-sensitive calcium pool and its change during synchronous division of Tetrahymena pyriformis cells].
A very significant intracellular pool of calcium, sensitive to digitonin action and different from one of free cytozolic Ca2+, has been shown to exist in the cells of ciliate protozoan T. pyriformis. Calcium content in digitonin-sensitive pool NdigCa2+ has been estimated throughout the cell cycle in synchronized culture of T. pyriformis. The value of NdigCa2+ decreased in the period of time prior to and at the cell division, whereas after the division itself it increased. The possible role of the calcium content changes of digitonin-sensitive pool in regulation of cytozolic Ca2+ level and in control of cell division is discussed.
Iorkov
I S
IS
Makarov
P R
PR
Azarashvili
T S
TS
Zinchenko
V P
VP
Kudzina
L Iu
LIu
Evtodienko
Iu V
IuV
D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002455:Cell Division / Q000187:drug effects*; D004072:Digitonin / Q000494:pharmacology*; D013769:Tetrahymena pyriformis / Q000166:cytology / Q000187:drug effects*
D004072:Digitonin; D002118:Calcium