title: In situ nitric oxide (NO) measurement by modified electrodes: NO labilized by photolysis of metal nitrosyl complexes.
abstract: Described are studies directed at refining quantitative analysis of nitric oxide in solution using electrochemical techniques. The fabrication and behavior of several sensors based on modified carbon-based electrodes are reported. This technique has been used to resolve the vexing problem of determining the stoichiometry of the photochemical decomposition of the known antihypertension agent sodium nitroprusside, Na2[Fe(CN)5NO], as well as of two other metal nitrosyl complexes of biological interest, Roussin's black salt, NH4[Fe4S3(NO)7], and Roussin's red salt, Na2[Fe2S2(NO)4], in aqueous solutions. In this manner it was shown that the molar ratios of nitric oxide produced per starting complex photochemically decomposed were 0.95 +/- 0.03, 5.9 +/- 0.2, and 0.50 +/- 0.02 for Na2[Fe(C-N)5NO], NH4[Fe4S3(NO)7], and Na2[Fe2S2(NO)4], respectively.
authors.affiliation: Department of Chemistry, University of California, Santa Barbara 93106-9510, USA.
authors.forename: S
authors.initials: S
authors.lastname: Kudo
authors.forename: J L
authors.initials: JL
authors.lastname: Bourassa
authors.forename: S E
authors.initials: SE
authors.lastname: Boggs
authors.forename: Y
authors.initials: Y
authors.lastname: Sato
authors.forename: P C
authors.initials: PC
authors.lastname: Ford
mesh_terms: D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods*; D004566:Electrodes; D006108:Graphite; D007502:Iron Chelating Agents / Q000737:chemistry / Q000528:radiation effects; D058085:Iron Compounds / Q000737:chemistry / Q000528:radiation effects; D008855:Microscopy, Electron, Scanning; D009569:Nitric Oxide / Q000032:analysis* / Q000737:chemistry / Q000528:radiation effects; D009599:Nitroprusside / Q000737:chemistry / Q000528:radiation effects; D009603:Nitroso Compounds; D010777:Photochemistry; D010782:Photolysis; D013499:Surface Properties
chemical_list: D007502:Iron Chelating Agents; D058085:Iron Compounds; D009603:Nitroso Compounds; D009599:Nitroprusside; D009569:Nitric Oxide; C078952:Roussin's Black Salt; C106536:Roussin's red salt; D006108:Graphite