title: In vitro dentine fluoride uptake from three fluoride-containing composites and their acid resistance.
abstract: OBJECTIVE
  The purpose of this study was to determine the dentine fluoride uptake from three fluoride-containing composites (FluorEver, FluoroCore and Pertac-Hybrid) and to investigate their ability to affect the resistance of dentine to an artificial caries challenge.
  
  
  METHODS
  Three dentine slabs were prepared from each tooth. The baseline, total and bound fluoride concentrations of each tooth were determined by three successive abrasion biopsies performed on each slab followed by adjusting to standardized depths of 10 microns. Next, dentine slabs ligated with the composites were suspended in synthetic saliva for 1 week. After removal of the composites, these specimens and controls were immersed in an artificial caries medium (pH 4.5) for 5 days. Each slab was sectioned and analysed by quantitative microradiography.
  
  
  RESULTS
  The results indicate that dentine acquired significantly different amounts of fluoride from the three composites. The acid resistance of dentine in contact with the composites was also significantly different among the composites and followed the same order as for fluoride uptake.
  
  
  CONCLUSIONS
  Dentine fluoride uptake and artificial caries inhibition were significantly greater with FluorEver followed by FluoroCore and Pertac-Hybrid.
authors.affiliation: Department of Operative Dentistry, Osaka University Faculty of Dentistry, Japan. kkawai@dent.osaka-u.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Kawai
authors.forename: T J
authors.initials: TJ
authors.lastname: Heaven
authors.forename: D H
authors.initials: DH
authors.lastname: Retief
mesh_terms: D001706:Biopsy / Q000379:methods; D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry; D002130:Calcium Phosphates / Q000737:chemistry; D002326:Cariogenic Agents / Q000737:chemistry; D002327:Cariostatic Agents / Q000032:analysis / Q000737:chemistry / Q000493:pharmacokinetics*; D003188:Composite Resins / Q000737:chemistry*; D003731:Dental Caries / Q000378:metabolism / Q000473:pathology; D003733:Dental Caries Susceptibility / Q000187:drug effects; D003738:Dental Cements / Q000737:chemistry; D003804:Dentin / Q000378:metabolism* / Q000648:ultrastructure; D005459:Fluorides / Q000032:analysis / Q000737:chemistry / Q000493:pharmacokinetics*; D005460:Fluorides, Topical / Q000737:chemistry; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007101:Immersion; D019344:Lactic Acid / Q000737:chemistry; D008852:Microradiography; D012464:Saliva, Artificial / Q000737:chemistry
chemical_list: D002130:Calcium Phosphates; D002326:Cariogenic Agents; D002327:Cariostatic Agents; D003188:Composite Resins; D003738:Dental Cements; D005460:Fluorides, Topical; C074316:FluoroCore; C079764:Pertac hybrid; D012464:Saliva, Artificial; C070190:FluorEver OBA; D019344:Lactic Acid; D017438:Bisphenol A-Glycidyl Methacrylate; D005459:Fluorides