Candida (Torulopsis glabrata) liver abscesses eight years after orthotopic liver transplantation.
The authors report the case of a 48-year-old man in whom candida (Torulopsis glabrata) liver abscesses developed 8 years after liver transplantation. After a week of fever, computed tomography and Doppler ultrasonography showed several fluid-filled loculations in the left lobe of the liver and hepatic arterial stenosis. Aspirates from the abscesses contained T. glabrata organisms. This complication probably developed because hepatic arterial stenosis resulted in bile infarcts (bilomas), which were contaminated via the biliary tract with candida from the biliary-enteric anastomosis. Catheter drainage and administration of amphotericin B for 10 weeks permitted successful retransplantation. T. glabrata liver abscesses, a life threatening complication that can occur long after liver transplantation, can be successfully managed by aggressive medical treatment followed by retransplantation.
Annunziata
G M
GM
Department of Medicine, University of Chicago Hospitals, Illinois 60637, USA.
Blackstone
M
M
Hart
J
J
Piper
J
J
Baker
A L
AL
D002177:Candidiasis / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008099:Liver / Q000473:pathology; D008100:Liver Abscess / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D016031:Liver Transplantation / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D012086:Reoperation; D014057:Tomography, X-Ray Computed; D018608:Ultrasonography, Doppler