title: High blood cadmium levels are not associated with consumption of traditional food among the Inuit of Nunavik.
abstract: High levels of cadmium in the liver and kidneys of caribous and sea mammals of the Canadian Arctic have led to recommendations to remove such offal from the traditional diet. Blood cadmium levels have been found to be very high in samples of Inuit volunteers, hence the hypothesis that the Inuit might be exposed to cadmium through their diet. This survey of a population-based random sample of Nunavik residents (n = 518) confirms that blood cadmium of Inuit is indeed very high by comparison to published reports. Blood cadmium levels are closely associated with the current smoking status and are independent of dietary patterns among nonsmokers. Plasma omega-3 fatty acids concentrations have been used to assess the reliability of the dietary information collected by questionnaires and to test for any association of blood cadmium with the consumption of sea mammals. Blood cadmium levels are not related to the reported consumption of sea mammals. Blood cadmium levels are very high among smokers and are associated with levels of exposure to tobacco. Among nonsmoking Inuit, blood cadmium levels are comparable with those reported in nonsmokers elsewhere in the world. In reference to international standards, blood cadmium concentrations are high enough among the Inuit to warrant energetic public health interventions.
authors.affiliation: Divisio de Epidemiologia, Instituto Nacional de Cancerologia, Santafe de Bogota, Colombia.
authors.forename: M
authors.initials: M
authors.lastname: Rey
authors.forename: F
authors.initials: F
authors.lastname: Turcotte
authors.forename: C
authors.initials: C
authors.lastname: Lapointe
authors.forename: E
authors.initials: E
authors.lastname: Dewailly
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002104:Cadmium / Q000097:blood*; D004032:Diet; D015525:Fatty Acids, Omega-3 / Q000097:blood; D005247:Feeding Behavior; D005260:Female; D006306:Health Surveys; D006801:Humans; D004930:Inuit; D008297:Male; D008460:Meat; D008875:Middle Aged; D011792:Quebec; D015203:Reproducibility of Results; D012907:Smoking; D011795:Surveys and Questionnaires
chemical_list: D015525:Fatty Acids, Omega-3; D002104:Cadmium