The effect of chairside relining materials on rat palatal mucosa.
OBJECTIVE
To investigate the effects of denture relining materials on oral mucosa in vivo in a rat model.


METHODS
Denture-like appliances covering the palate in Wistar rats were relined with a resilient soft linting material and a hard 'chairside' relining material. The effects on the palatal epithelium were studied by quantitative analysis using computerized planimetry.


RESULTS
The relining materials caused an increase in the thickness of the keratinized layer, while not increasing the total epithelial thickness.


CONCLUSIONS
Relining materials are not totally without effect on oral mucosa. Further in vivo research is indicated.
Barclay
S C
SC
Department of Prosthodontics, Glasgow Dental Hospital and School NHS Trust, UK.
MacDonald
D G
DG
Watson
I B
IB
D000180:Acrylic Resins / Q000494:pharmacology*; D000818:Animals; D001485:Basement Membrane / Q000187:drug effects / Q000473:pathology; D003819:Denture Bases; D003822:Denture Liners; D003823:Denture Rebasing; D004195:Disease Models, Animal; D004548:Elasticity; D004848:Epithelium / Q000187:drug effects / Q000473:pathology; D007633:Keratins; D008297:Male; D008689:Methacrylates / Q000494:pharmacology; D008768:Methylmethacrylates / Q000494:pharmacology; D009061:Mouth Mucosa / Q000187:drug effects* / Q000473:pathology; D010159:Palate / Q000187:drug effects* / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar; D013499:Surface Properties
D000180:Acrylic Resins; D008689:Methacrylates; D008768:Methylmethacrylates; C103363:kooliner; C069457:Coe-Soft denture lining material; D007633:Keratins; C009931:poly(ethylmethacrylate)