title: Interstitial pregnancy managed medically. A case report.
abstract: BACKGROUND
  Interstitial pregnancies are often associated with significant morbidity. The surgical treatment of such ectopic gestations often requires laparotomy and cornual resection, thus obliterating tubal and uterine continuity. Methotrexate has been shown to be 94% successful in the management of tubally implanted ectopic gestations, but few reports describe its use in interstitial pregnancies.
  
  
  METHODS
  An 18-year-old woman who presented with an asymptomatic interstitial pregnancy was treated successfully with intramuscular methotrexate. Laparotomy and cornual resection were avoided. No adverse effects were noted.
  
  
  CONCLUSIONS
  Interstitial pregnancies can be treated successfully with intramuscular methotrexate.
authors.affiliation: Department of Obstetrics, Gynecology and Reproductive Sciences, University of Texas Medical School at Houston 77030, USA.
authors.forename: L S
authors.initials: LS
authors.lastname: Swaim
authors.forename: N F
authors.initials: NF
authors.lastname: Maklad
mesh_terms: D000293:Adolescent; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000097:blood; D005260:Female; D005493:Folic Acid Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007273:Injections, Intramuscular; D008727:Methotrexate / Q000008:administration & dosage / Q000627:therapeutic use*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000097:blood / Q000188:drug therapy*
chemical_list: D018997:Chorionic Gonadotropin, beta Subunit, Human; D005493:Folic Acid Antagonists; D008727:Methotrexate