Growth-associated protein GAP-43 detection in the neuronal somata following middle cerebral artery occlusion in the rat.
We first detected growth-associated protein (GAP-43) immunoreactivity in the neuronal somata following middle cerebral artery occlusion in the rat. Four days after the middle cerebral artery occlusion, GAP-43 immunoreactivity was detected in some cortical neurons of the ischemic penumbra at the level of the hippocampus.
Furuya
K
K
Department of Neurosurgery, Teikyo University School of Medicine, Tokyo, Japan.
Kawai
K
K
Asai
A
A
Tamura
A
A
D000818:Animals; D001157:Arterial Occlusive Diseases / Q000378:metabolism* / Q000473:pathology; D015153:Blotting, Western; D002536:Cerebral Arteries; D019922:GAP-43 Protein; D007158:Immunologic Techniques; D008297:Male; D008562:Membrane Glycoproteins / Q000378:metabolism*; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*; D016548:Prosencephalon / Q000378:metabolism / Q000473:pathology; D051381:Rats; D017207:Rats, Sprague-Dawley; D014018:Tissue Distribution
D019922:GAP-43 Protein; D008562:Membrane Glycoproteins; D009419:Nerve Tissue Proteins