title: [Metabolism of nicotine--mechanism and clinical effects of toxicity].
abstract: Nicotine is a major constituent of tobacco and exerts a number of physiological effects. Metabolism of nicotine in animal and human tissues is reviewed. Clinical considerations regarding the problems of toxic effects of nicotine in human and molecular basis of carcinogen mechanism of nicotine derivatives are discussed.
authors.affiliation: Katedra i Zakład Biochemii Akademii Medycznej we Wrocławiu.
authors.forename: G
authors.initials: G
authors.lastname: Szajerka
authors.forename: D
authors.initials: D
authors.lastname: Kwiatkowska
mesh_terms: D000818:Animals; D002273:Carcinogens / Q000378:metabolism / Q000633:toxicity; D004247:DNA / Q000187:drug effects; D006801:Humans; D009538:Nicotine / Q000378:metabolism* / Q000633:toxicity*
chemical_list: D002273:Carcinogens; D009538:Nicotine; D004247:DNA