title: 9-Benzyladenines: potent and selective cAMP phosphodiesterase inhibitors.
authors.affiliation: Laboratoire de Pharmacochimie Moléculaire, UPR 421 du CNRS, Strasbourg, France.
authors.forename: J J
authors.initials: JJ
authors.lastname: Bourguignon
authors.forename: L
authors.initials: L
authors.lastname: Désaubry
authors.forename: P
authors.initials: P
authors.lastname: Raboisson
authors.forename: C G
authors.initials: CG
authors.lastname: Wermuth
authors.forename: C
authors.initials: C
authors.lastname: Lugnier
mesh_terms: D015105:3',5'-Cyclic-AMP Phosphodiesterases / Q000037:antagonists & inhibitors*; D000225:Adenine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D058892:Adenosine Deaminase Inhibitors; D000927:Anticonvulsants; D000242:Cyclic AMP / Q000494:pharmacology; D006152:Cyclic GMP / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D007527:Isoenzymes / Q000037:antagonists & inhibitors*; D009131:Muscle, Smooth, Vascular / Q000201:enzymology; D011687:Purines / Q000737:chemistry* / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: C106583:2-trifluoromethyl-9-(2-fluorophenylmethyl)-N-methyladenine; D058892:Adenosine Deaminase Inhibitors; D000927:Anticonvulsants; D004791:Enzyme Inhibitors; D007527:Isoenzymes; D011687:Purines; C050493:9-(2-fluorobenzyl)-6-(methylamino)-9H-purine; C010192:9-(2-hydroxy-3-nonyl)adenine; D000242:Cyclic AMP; D015105:3',5'-Cyclic-AMP Phosphodiesterases; D006152:Cyclic GMP; D000225:Adenine