title: The results of anthelmintic-abbreviated infections of Trichostrongylus colubriformis and Teladorsagia circumcincta on fecal egg counts in goats on pasture.
abstract: Twenty, 2-yr-old angora goats kept on nematode larvae-contaminated pasture since birth were divided into 2 equal groups. Goats from group 1 were immunized by drug-abbreviated infection, a procedure that gave high protection against field challenge in 12-moold sheep. Group 1 was orally dosed 3 times with increasing numbers of Trichostrongylus colubriformis and Teladorsagia circumcincta infective larvae. Each time, the infection was abbreviated with Oxfendazole (OXF) 15 days after dosing. Group 2 received only OXF. After the third dose of OXF, the goats were grazed together on the same pasture and fecal egg counts determined. No protection in immunized goats was achieved. In fact, immunized goats produced significantly more nematode eggs than the nonimmunized group.
authors.affiliation: AgResearch, Wallaceville Animal Research Centre, Upper Hutt, New Zealand.
authors.forename: E
authors.initials: E
authors.lastname: Hadas
authors.forename: M
authors.initials: M
authors.lastname: Stankiewicz
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D000969:Antinematodal Agents / Q000494:pharmacology / Q000627:therapeutic use; D001562:Benzimidazoles / Q000494:pharmacology / Q000627:therapeutic use; D004198:Disease Susceptibility; D005243:Feces / Q000469:parasitology; D005260:Female; D015511:Goat Diseases / Q000188:drug therapy / Q000517:prevention & control*; D006041:Goats; D007114:Immunization / Q000009:adverse effects / Q000379:methods / Q000662:veterinary*; D008297:Male; D010270:Parasite Egg Count / Q000662:veterinary; D014251:Trichostrongyloidea / Q000187:drug effects / Q000254:growth & development / Q000276:immunology; D014252:Trichostrongyloidiasis / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary*; D014253:Trichostrongylosis / Q000188:drug therapy / Q000517:prevention & control / Q000662:veterinary*; D014254:Trichostrongylus / Q000187:drug effects / Q000254:growth & development / Q000276:immunology
chemical_list: D000969:Antinematodal Agents; D001562:Benzimidazoles; C011030:oxfendazole