Osteoporosis: a view into the next century.
Osteoporosis is a systemic disease in which fractures in later life result from gradual deterioration of bone mass and architecture. It will become an increasingly serious problem world-wide as the population ages and as a result of a secular trend that is not well understood. A review of information on the geographical variation of osteoporosis is followed by a consideration of the possible effects of calcium, smoking and exercise. The problem of osteoporosis will be very difficult to tackle, but the best preventive approach is probably to develop a screening strategy for women well after the menopause-perhaps at 65 years-and to target interventions to those at highest risk.
Kanis
J A
JA
Department of Human Metabolism and Clinical Biochemistry, University of Sheffield Medical School, UK.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis