Primary transplantation of allogeneic peripheral blood stem cell for severe aplastic anemia.
Primary allogeneic peripheral blood stem cell transplantation (allo-PBSCT) has not been previously described in the treatment of severe aplastic anemia (SAA). We report a patient with SAA who underwent primary allo-PBSCT with cells from her HLA-identical sibling and achieved rapid bone marrow reconstitution. The patient has been in complete remission with normal blood counts for 9 months following allo-PBSCT. This suggests that primary allo-PBSCT is a safe and effective alternative in the treatment of SAA.
Hsu
H C
HC
Department of Medicine, Veterans General Hospital-Taipei, Taiwan, Republic of China.
Tsai
W H
WH
Lin
J S
JS
Tzeng
C H
CH
Wang
S Y
SY
Ho
C H
CH
D000293:Adolescent; D000741:Anemia, Aplastic / Q000628:therapy*; D016572:Cyclosporine / Q000627:therapeutic use; D005260:Female; D006086:Graft vs Host Disease / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007963:Leukocytes, Mononuclear / Q000166:cytology*; D033581:Stem Cell Transplantation; D014184:Transplantation, Homologous
D007166:Immunosuppressive Agents; D016572:Cyclosporine