Births after transcervical gamete intrafallopian transfer with a falloposcopic delivery system.
OBJECTIVE
To evaluate the safety and efficiency of a new delivery system to perform transcervical GIFT.


METHODS
Evaluation of pregnancy rate (PR), miscarriage rate, ectopic pregnancy rate, and delivery rate.


METHODS
Institute of Obstetrics and Gynecology, Reproductive Endocrinology Unit, Infertility and IVF Center.


METHODS
Twenty-five patients with patent tubes documented by laparoscopy plus falloposcopy.


METHODS
Superovulation was induced with GnRH analogue and FSH. Under laparoscopic control, transcervical cannulation of the tube was done using a linear everting catheter incorporating direct falloposcopic vision of the tubal lumen. Two lengths of everting catheter (3 and 6 cm) were used providing either isthmic-ampullary or midampullary placement of the inoculum. A comparison was done in terms of ease of access and transfer, falloposcopic observations, and PRs between the groups.


METHODS
Efficacy was established by evaluating the PR, miscarriage rate, ectopic pregnancy rate, and delivery rate.


RESULTS
The PR was 28% (with no differences between the lengths of everting catheters). No ectopic pregnancies occurred. The abortion rate was 28.6% and the delivery rate was 20%. Neither tubal perforation nor other complications occurred during the procedure.


CONCLUSIONS
Falloposcopic GIFT is safe and efficient and may be a less invasive alternative than laparoscopic transfer.
Porcu
E
E
Institute of Obstetrics and Gynaecology, University of Bologna, Italy.
Dal Prato
L
L
Seracchioli
R
R
Petracchi
S
S
Fabbri
R
R
Flamigni
C
C
D000022:Abortion, Spontaneous / Q000453:epidemiology; D002584:Cervix Uteri; D006063:Chorionic Gonadotropin; D004624:Embryo Transfer / Q000295:instrumentation / Q000379:methods; D005260:Female; D015181:Gamete Intrafallopian Transfer / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods; D006801:Humans; D007231:Infant, Newborn; D010535:Laparoscopy; D008186:Luteolytic Agents; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000453:epidemiology; D012449:Safety; D013480:Superovulation; D017329:Triptorelin Pamoate
D006063:Chorionic Gonadotropin; D008186:Luteolytic Agents; D017329:Triptorelin Pamoate