[Seasonal changes of laboratory data in patients with Japanese cedar pollinosis].
Japanese cedar pollen (JCP) causes a significant seasonal allergic rhinitis in Japan during the early spring. Blood samples were collected monthly from October 1993 through October 1994 from 11 patients with Japanese cedar pollinosis. The patients were segregated into two categories based on specific IgE (RAST): single positive RAST to JCP only and multiple positive RAST to JCP, house dust (H1) and mite (D1). These two populations differed in levels of total serum IgE, numbers of eosinophils, basophils and neutrophils in peripheral blood and clinical symptoms. Seasonal increase of JCP-specific IgE was observed after pollen season in both groups. In the single positive group, but not in the multiple positive group, seasonal increase of the number of eosinophils in peripheral blood was observed with post seasonal fall and the level of total serum IgE was increased in the same manner as that of the JCP specific IgE. Although it was not significant, there was a broad seasonal increase of serum nitrate anion, a metabolite of nitric oxide.
Fujiwara
H
H
Central Laboratory, Kansai Medical University Hospital, Moriguchi.
Masuda
M
M
Kubo
N
N
Okochi
H
H
Shimoshikiryo
K
K
Okamoto
H
H
Hara
K
K
Ogawa
N
N
Takahashi
H
H
D000328:Adult; D000818:Animals; D001491:Basophils; D004804:Eosinophils; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood*; D007564:Japan; D007958:Leukocyte Count; D008297:Male; D009569:Nitric Oxide / Q000097:blood; D011058:Pollen / Q000276:immunology*; D011852:Radioallergosorbent Test; D006255:Rhinitis, Allergic, Seasonal / Q000276:immunology*; D012621:Seasons
D009569:Nitric Oxide; D007073:Immunoglobulin E