Current status of photodynamic therapy in dermatology.
The accessibility of skin to light treatment, as well as the expertise developed by dermatologists in laser surgery and phototherapy, creates an exciting opportunity for dermatologic PDT to become part of our standard therapeutic armamentarium. PDT appears to be viable alternative to conventional therapy for superficial BCC and Bowen's disease, although definitive controlled studies are lacking. The introduction of ongoing research developments, new photosensitizers, and better light sources into clinical PDT trials in the coming years will undoubtedly expand the range of indications for this novel form of therapy, particularly for nononcologic conditions.
Bissonnette
R
R
Division of Dermatology, Vancouver Hospital, University of British Columbia, Canada.
Lui
H
H
D006801:Humans; D010778:Photochemotherapy / Q000009:adverse effects / Q000379:methods; D012871:Skin Diseases / Q000188:drug therapy*