title: Neonatal septic arthritis.
abstract: Neonatal septic arthritis has always been considered as separate from its counterpart in older children. The condition is uncommon but serious. Affected neonates usually survive, but with permanent skeletal deformities. Ten cases of neonatal septic arthritis were diagnosed between January 1989 and December 1993 in the neonatal intensive care units of two referral hospitals in the state of Kelantan, Malaysia. All except one neonate was born prematurely. The mean age of presentation was 15.6 days. Joint swelling (10/10), increased warmth (7/10) and erythema of the overlying skin (7/10) were the common presenting signs. Vague constitutional symptoms preceded the definitive signs of septic arthritis in all cases. The total white cell counts were raised with shift to the left. The knee (60%) was not commonly affected, followed by the hip (13%) and ankle (13%). Three neonates had multiple joint involvement. Coexistence of arthritis with osteomyelitis was observed in seven neonates. The commonest organism isolated was methicillin resistant Staphylococcus aureus (9/10). Needle aspiration was performed in nine neonates and one had incision with drainage. Follow up data was available for five neonates and two of these had skeletal morbidity. Early diagnosis by frequent examination of the joints, prompt treatment and control of nosocomial infection are important for management.
authors.affiliation: Department of Pediatrics, Hospital Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia.
authors.forename: D
authors.initials: D
authors.lastname: Halder
authors.forename: Q B
authors.initials: QB
authors.lastname: Seng
authors.forename: A S
authors.initials: AS
authors.lastname: Malik
authors.forename: K E
authors.initials: KE
authors.lastname: Choo
mesh_terms: D017668:Age of Onset; D001170:Arthritis, Infectious / Q000453:epidemiology* / Q000382:microbiology / Q000503:physiopathology / Q000628:therapy; D015897:Comorbidity; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology / Q000503:physiopathology / Q000628:therapy; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D015931:Intensive Care, Neonatal; D007710:Klebsiella Infections / Q000453:epidemiology; D008296:Malaysia / Q000453:epidemiology; D008297:Male; D016106:Methicillin Resistance; D010019:Osteomyelitis / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000453:epidemiology; D013211:Staphylococcus aureus