Growth inhibition of transplantable mouse tumors by non-digestible carbohydrates.
The possible influence of dietary non-digestible carbohydrates (15% oligofructose, inulin or pectin incorporated in basal diet) on the growth of intramuscularily transplanted mouse tumors, from 2 tumor lines (TLT and EMT6), was investigated. The results were evaluated by regular tumor measurements with Vernier caliper. Mean tumor surface in experimental groups was compared with that in animals of control group fed basal diet containing starch as the only carbohydrate. The growth of both tumor lines was significantly inhibited by supplementation of non-digestible carbohydrates.
Taper
H S
HS
Département des sciences pharmaceutiques, Université catholique de Louvain, Brussels, Belgium.
Delzenne
N M
NM
Roberfroid
M B
MB
D000818:Animals; D002455:Cell Division / Q000187:drug effects*; D004040:Dietary Carbohydrates / Q000494:pharmacology*; D005260:Female; D051379:Mice; D008807:Mice, Inbred BALB C; D009368:Neoplasm Transplantation; D009374:Neoplasms, Experimental / Q000473:pathology*
D004040:Dietary Carbohydrates