title: Tear lactoferrin concentration during postoperative ocular inflammation in cataract surgery.
abstract: Tear lactoferrin concentration was measured by ELISA technique and followed in 30 patients undergoing cataract surgery. On the first day following surgery, there was a significant decrease in tear lactoferrin concentration followed by a gradual return to the initial values during the postoperative observation period of 7 days. There was an inverse linear relationship between tear lactoferrin concentration and the tear secretion rate measured by a modified Schirmer I test (1 min) suggesting a constant lactoferrin secretion by the tear glands. Since lactoferrin has known antibacterial and anti-inflammatory effects, the results may contribute to further understanding of the microbial vulnerability or resistance of the eye following surgical procedures.
authors.affiliation: Department of Ophthalmology, Pt. B.D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, India.
authors.forename: R
authors.initials: R
authors.lastname: Kumar
authors.forename: I P
authors.initials: IP
authors.lastname: Parmar
authors.forename: N
authors.initials: N
authors.lastname: Chhillar
authors.forename: H
authors.initials: H
authors.lastname: Lal
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction / Q000009:adverse effects; D009877:Endophthalmitis / Q000209:etiology / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007765:Lacrimal Apparatus / Q000378:metabolism; D007781:Lactoferrin / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology / Q000378:metabolism*; D011184:Postoperative Period; D013666:Tears / Q000378:metabolism*
chemical_list: D007781:Lactoferrin