title: Mercury dynamics in hair of rats exposed to methylmercury by synchrotron radiation X-ray fluorescence imaging.
abstract: Two-dimensional distribution of mercury (Hg) in hair samples of rats exposed to methylmercury (MeHg) was analyzed by synchrotron radiation X-ray fluorescence (SR-XRF) imaging. Experiments with endogenous- and exogenous-model for MeHg exposure revealed that the metal level was obviously higher in the hair cortex after the former exposure whereas a dominant site that Hg distributed after the latter exposure was the cuticle. The method also provided us the Hg profile along the hair length with a single hair obtained by the endogenous model. Thus application of SR-XRF analysis to hair sample would facilitate biological monitoring to not only distinct Hg exposure but also determine its dynamics with only the specimen.
authors.affiliation: Department of Environmental Medicine, Institute of Community Medicine, University of Tsukuba, Ibaraki, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Shimojo
authors.forename: S
authors.initials: S
authors.lastname: Homma-Takeda
authors.forename: K
authors.initials: K
authors.lastname: Ohuchi
authors.forename: M
authors.initials: M
authors.lastname: Shinyashiki
authors.forename: G F
authors.initials: GF
authors.lastname: Sun
authors.forename: Y
authors.initials: Y
authors.lastname: Kumagai
mesh_terms: D000818:Animals; D006197:Hair / Q000737:chemistry*; D008297:Male; D008628:Mercury / Q000032:analysis*; D008767:Methylmercury Compounds / Q000008:administration & dosage*; D051381:Rats; D017208:Rats, Wistar; D013052:Spectrometry, X-Ray Emission
chemical_list: D008767:Methylmercury Compounds; D008628:Mercury