[The effect of naloxone and leu-enkephalin on the atretic changes in the ovarian follicles of hypophysectomized rats].
In 21--23-day-old female Wistar rats with atresia of the ovarian follicles, naloxone administration increased the number of 100-200 mcm follicles with atresia-induced changes, whereas enkephaline prevented the effect. Role of the brain opioid system in the above phenomenon, is discussed.
Zaporozhchenko
M B
MB
Andrievskiĭ
A G
AG
D000704:Analysis of Variance; D000818:Animals; D004054:Diethylstilbestrol / Q000494:pharmacology; D004743:Enkephalin, Leucine / Q000494:pharmacology*; D004968:Estrogens, Non-Steroidal / Q000494:pharmacology; D005260:Female; D005496:Follicular Atresia / Q000187:drug effects* / Q000502:physiology; D007016:Hypophysectomy; D009270:Naloxone / Q000494:pharmacology*; D009292:Narcotic Antagonists / Q000494:pharmacology*; D010902:Pituitary Gland / Q000502:physiology*; D051381:Rats; D017208:Rats, Wistar; D011957:Receptors, Opioid / Q000819:agonists*; D013997:Time Factors
D004968:Estrogens, Non-Steroidal; D009292:Narcotic Antagonists; D011957:Receptors, Opioid; D009270:Naloxone; D004743:Enkephalin, Leucine; D004054:Diethylstilbestrol