title: Polycyclic aromatic hydrocarbon-DNA adducts in beluga whales from the Arctic.
abstract: The Arctic is still relatively pristine in nature, but it is also vulnerable to pollution because contaminants originating from midlatitudes are transported to the Arctic by atmospheric processes, ocean currents, and rivers (Muir et al., 1992). Recognition of this fact of Arctic vulnerability has resulted in a Declaration on the Protection of the Arctic Environment by eight Arctic countries. A manifest aim of this declaration is to develop an Arctic Monitoring and Assessment Program. We report here on the presence of measurable levels of polycyclic aromatic hydrocarbon-DNA adducts, including relatively high levels in Arctic beluga (Delphinapterus leucas). These results lend support to the value of developing biological assessment programs for Arctic wildlife.
authors.affiliation: Department of Fisheries and Oceans, St. John's, Newfoundland, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Mathieu
authors.forename: J F
authors.initials: JF
authors.lastname: Payne
authors.forename: L L
authors.initials: LL
authors.lastname: Fancey
authors.forename: R M
authors.initials: RM
authors.lastname: Santella
authors.forename: T L
authors.initials: TL
authors.lastname: Young
mesh_terms: D000818:Animals; D001110:Arctic Regions; D001921:Brain / Q000187:drug effects*; D002273:Carcinogens / Q000633:toxicity*; D004247:DNA / Q000187:drug effects; D018736:DNA Adducts / Q000032:analysis*; D004249:DNA Damage; D004797:Enzyme-Linked Immunosorbent Assay; D007668:Kidney / Q000187:drug effects*; D008099:Liver / Q000187:drug effects*; D008297:Male; D011084:Polycyclic Aromatic Hydrocarbons / Q000633:toxicity*; D014907:Whales
chemical_list: D002273:Carcinogens; D018736:DNA Adducts; D011084:Polycyclic Aromatic Hydrocarbons; D004247:DNA