title: Comparison of Tc-99m sestamibi perfusion imaging and echocardiography using an arbutamine infusion for the detection of coronary artery disease.
abstract: Arbutamine, a synthetic catecholamine, coupled with a closed-loop, computerized delivery system was evaluated in conjunction with technetium-99m sestamibi scintigraphy and echocardiography for the detection of coronary artery disease. Concordance between the imaging methods was 68%, with a similar sensitivity for coronary disease using echocardiography (78%) and technetium-99m sestamibi (76%), although more arbutamine-induced ischemia was noted with perfusion imaging.
authors.affiliation: Northwestern University Medical School, Chicago, Illinois 60611, USA.
authors.forename: R C
authors.initials: RC
authors.lastname: Hendel
authors.forename: W
authors.initials: W
authors.lastname: Kostuk
authors.forename: R S
authors.initials: RS
authors.lastname: Beanlands
authors.forename: F
authors.initials: F
authors.lastname: Chaudry
authors.forename: K J
authors.initials: KJ
authors.lastname: Ascah
authors.forename: H
authors.initials: H
authors.lastname: Young
authors.forename: T D
authors.initials: TD
authors.lastname: Ruddy
mesh_terms: D000318:Adrenergic beta-Agonists; D002395:Catecholamines; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D003331:Coronary Vessels / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D004452:Echocardiography / Q000379:methods*; D006801:Humans; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi
chemical_list: D000318:Adrenergic beta-Agonists; D002395:Catecholamines; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi; C076559:arbutamine