title: [Correlation between prostate specific antigen and histopathologic findings in ileum-obturator node dissection].
abstract: OBJECTIVE
  To determine the correlation between PSA values and the histopathological findings of ileo-obturator node dissection in prostatic cancer.
  
  
  METHODS
  We reviewed the data of 51 patients with clinically localized prostatic carcinoma, submitted to ileo-obturator node dissection before definitive treatment of the tumor. The patients were classified into 4 groups according to their previous PSA values: A < 10 ng/ml, B > 10 and < 20 ng/ml, C > 20 and < 50 ng/ml and D < 50 ng/ml.
  
  
  RESULTS
  Overall 17.6% of the patients had positive lymph nodes; 9.9% of the patients in group A, 15.4% of the patients in group B, 11.1% of those in group C and 41.7% of those in group D had positive nodes. Using 50 ng/ml as the cut-off point, 10% of those with PSA < 50 ng/ml had positive nodes vs 42.3% of those with PSA > 50 ng/ml, which was statistically significant with the Fischer test.
  
  
  CONCLUSIONS
  Preoperative PSA has a statistically significant correlation with positive nodes, considering 50 ng/ml as the cut-off point. PSA determination in patients that have received no treatment is essential in the diagnosis and evaluation of therapy in prostate cancer.
authors.affiliation: Servicio de Urología, Hospital de Clínicas José de San Martín, Buenos Aires, Argentina.
authors.forename: C
authors.initials: C
authors.lastname: Scorticati
authors.forename: L
authors.initials: L
authors.lastname: Montes de Oca
authors.forename: F
authors.initials: F
authors.lastname: Bencardino
authors.forename: M
authors.initials: M
authors.lastname: López
authors.forename: P
authors.initials: P
authors.lastname: Suárez
authors.forename: N
authors.initials: N
authors.lastname: Bernardo
authors.forename: J
authors.initials: J
authors.lastname: Rozanec
authors.forename: O
authors.initials: O
authors.lastname: Bellora
authors.forename: P
authors.initials: P
authors.lastname: Holst
authors.forename: F
authors.initials: F
authors.lastname: Coste Delvecchio
authors.forename: C
authors.initials: C
authors.lastname: Scorticati
mesh_terms: D000230:Adenocarcinoma / Q000097:blood* / Q000473:pathology*; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood* / Q000473:pathology*; D012189:Retrospective Studies
chemical_list: D017430:Prostate-Specific Antigen