title: Transient P300 abnormality of event-related potentials following unilateral temporal lobectomy.
abstract: Event-related potentials (ERP) were recorded during auditory oddball tasks for a patient prior to and soon after left anterior temporal lobectomy. The N100 amplitude decreased bilaterally although the latency did not change after the lobectomy. The P300 amplitude decreased in the left hemisphere at 1 and 2 weeks after surgery, then recovered to the pre-operative level at 4 weeks. These findings suggest that the medial temporal structure participates in the generating system of P300.
authors.affiliation: Department of Neuropsychiatry, Faculty of Medicine, University of the Ryukyus, Okinawa, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Hirayasu
authors.forename: H
authors.initials: H
authors.lastname: Ohta
authors.forename: K
authors.initials: K
authors.lastname: Fukao
authors.forename: C
authors.initials: C
authors.lastname: Ogura
authors.forename: J
authors.initials: J
authors.lastname: Mukawa
mesh_terms: D000328:Adult; D004830:Epilepsy, Tonic-Clonic / Q000503:physiopathology / Q000601:surgery; D018913:Event-Related Potentials, P300 / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D013702:Temporal Lobe / Q000502:physiology* / Q000601:surgery*