Receptor-mediated activation of a MAP kinase in pathogen defense of plants.
Parsley cells recognize the fungal plant pathogen Phytophthora sojae through a plasma membrane receptor. A pathogen-derived oligopeptide elicitor binds to this receptor and thereby stimulates a multicomponent defense response through sequential activation of ion channels and an oxidative burst. An elicitor-responsive mitogen-activated protein (MAP) kinase was identified that acts downstream of the ion channels but independently or upstream of the oxidative burst. Upon receptor-mediated activation, the MAP kinase is translocated to the nucleus where it might interact with transcription factors that induce expression of defense genes.
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Institute of Microbiology and Genetics, Vienna Biocenter, Dr.-Bohr-Gasse 9, A-1030 Vienna, Austria.
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D000595:Amino Acid Sequence; D000666:Amphotericin B / Q000494:pharmacology; D000873:Anthracenes / Q000494:pharmacology; D017871:Calcium-Calmodulin-Dependent Protein Kinases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D002467:Cell Nucleus / Q000201:enzymology; D002478:Cells, Cultured; D004789:Enzyme Activation; D005656:Fungal Proteins / Q000494:pharmacology*; D007473:Ion Channels / Q000187:drug effects / Q000378:metabolism; D008562:Membrane Glycoproteins / Q000494:pharmacology*; D008969:Molecular Sequence Data; D009861:Onium Compounds / Q000494:pharmacology; D010446:Peptide Fragments / Q000494:pharmacology; D010766:Phosphorylation; D010838:Phytophthora / Q000378:metabolism; D010944:Plants / Q000201:enzymology* / Q000235:genetics / Q000382:microbiology; D016897:Respiratory Burst / Q000187:drug effects
D000873:Anthracenes; D005656:Fungal Proteins; D007473:Ion Channels; D008562:Membrane Glycoproteins; D009861:Onium Compounds; D010446:Peptide Fragments; C091510:elicitor protein, Phytophthora megasperma; C007517:diphenyleneiodonium; C010030:9-anthroic acid; D000666:Amphotericin B; D017871:Calcium-Calmodulin-Dependent Protein Kinases