Mutations to the alpha-2 domain of human class II molecules alters the efficiency of peptide loading and antigen presentation.
Lamikanra
A
A
Department of Crystallography, Birkbeck College, UK.
Grüneberg
U
U
Altmann
D
D
Travers
P
P
D000911:Antibodies, Monoclonal; D000918:Antibody Specificity; D000939:Epitopes / Q000276:immunology; D006684:HLA-DR Antigens / Q000096:biosynthesis / Q000737:chemistry* / Q000276:immunology*; D006801:Humans; D008213:Lymphocyte Activation; D016297:Mutagenesis, Site-Directed; D017354:Point Mutation; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000737:chemistry / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*; D014162:Transfection
D000911:Antibodies, Monoclonal; D000939:Epitopes; D006684:HLA-DR Antigens; D011994:Recombinant Proteins