title: Overdose, suicide attempts and death among a cohort of naltrexone-treated opioid addicts.
abstract: In a study evaluating naltrexone with either an intensive psychosocial protocol or standard community treatment for opioid dependence, 13 of 81 subjects overdosed within a 12-month period of study participation. There were four fatalities, one of which was a suicide. Among the nine nonfatal overdoses, there were four suicide attempts. Characteristics of subjects and naltrexone-taking are described.
authors.affiliation: Matrix Center, Los Angeles, CA, USA.
authors.forename: K
authors.initials: K
authors.lastname: Miotto
authors.forename: M J
authors.initials: MJ
authors.lastname: McCann
authors.forename: R A
authors.initials: RA
authors.lastname: Rawson
authors.forename: D
authors.initials: D
authors.lastname: Frosch
authors.forename: W
authors.initials: W
authors.lastname: Ling
mesh_terms: D000328:Adult; D003866:Depressive Disorder / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D009271:Naltrexone / Q000009:adverse effects / Q000627:therapeutic use*; D009292:Narcotic Antagonists / Q000009:adverse effects / Q000627:therapeutic use*; D009294:Narcotics / Q000506:poisoning*; D009293:Opioid-Related Disorders / Q000188:drug therapy* / Q000401:mortality* / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D011613:Psychotherapy; D013406:Suicide, Attempted / Q000523:psychology*
chemical_list: D009292:Narcotic Antagonists; D009294:Narcotics; D009271:Naltrexone