Sequential activity in human motor areas during a delayed cued finger movement task studied by time-resolved fMRI.
Activity in the human primary motor cortex, the premotor cortex and the supplementary motor area during a delayed cued finger movement task was measured by time-resolved functional magnetic resonance imaging. Activity during movement preparation can be resolved from activity during movement execution in a single trial. All three areas were active during both movement preparation and movement execution. Activity in the primary motor cortex was considerably weaker during movement preparation than during movement execution; in the premotor cortex and the supplementary motor area, activity was of similar intensity during both periods. These observations are consistent with results from single neuronal recording studies in primates.
Richter
W
W
Center for Magnetic Resonance Research, University of Minnesota Medical School, Minneapolis 55455, USA.
Andersen
P M
PM
Georgopoulos
A P
AP
Kim
S G
SG
D001931:Brain Mapping / Q000379:methods*; D003463:Cues; D004576:Electromyography; D005260:Female; D005385:Fingers; D005625:Frontal Lobe / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009044:Motor Cortex / Q000473:pathology / Q000502:physiology*; D009068:Movement / Q000502:physiology*; D010296:Parietal Lobe / Q000502:physiology; D011930:Reaction Time / Q000502:physiology*; D013997:Time Factors