title: [Creutzfeldt-Jakob disease; one year later].
abstract: During the last year the knowledge of the transmission of prion diseases has increased. New diagnostic methods were developed: investigation of cerebrospinal fluid for the 14-3-3 protein and tonsillar biopsy to detect protease resistant prion protein. Indirect evidence of a causal relation between new variant Creutzfeldt-Jakob disease (nvCJ) and bovine spongiform encephalopathy (BSE) is accumulating, although epidemiological data do not indicate that the incidence of CJ is increasing.
authors.affiliation: Academisch Medisch Centrum, afd. Neurologie, Amsterdam.
authors.forename: W A
authors.initials: WA
authors.lastname: van Gool
authors.forename: P H
authors.initials: PH
authors.lastname: Meijerink
mesh_terms: D000328:Adult; D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000635:transmission; D007562:Creutzfeldt-Jakob Syndrome / Q000134:cerebrospinal fluid / Q000453:epidemiology* / Q000635:transmission; D004196:Disease Outbreaks; D016643:Encephalopathy, Bovine Spongiform / Q000635:transmission; D006801:Humans; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D011328:Prions / Q000134:cerebrospinal fluid; D006113:United Kingdom / Q000453:epidemiology
chemical_list: D011328:Prions