Bronchiectasis in bone marrow transplantation.
Two patients are described with clinical and radiographic bronchiectasis which occurred after allogeneic bone marrow transplantation for haematological malignancy. Both had evidence of chronic graft versus host disease in other organs. Increased immunosuppression with corticosteroids resulted in clinical response, although both patients persisted with chronic mucopurulent sputum production and one had progressive airflow obstruction. Bronchiectasis may be an under-recognised manifestation of chronic graft versus host disease of the lung.
Morehead
R S
RS
Division of Pulmonary Medicine, Veterans Affairs Medical Center, Lexington, Kentucky, USA.
D000328:Adult; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D001987:Bronchiectasis / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D006086:Graft vs Host Disease / Q000150:complications*; D019337:Hematologic Neoplasms / Q000628:therapy; D006801:Humans; D008297:Male; D011183:Postoperative Complications; D014057:Tomography, X-Ray Computed