title: Vaccination trials against Taiwan Taenia eggs in pigs injected with frozen oncospheres of Taiwan Taenia, Korea Taenia, T. saginata or T. solium.
abstract: When Small-Ear-Miniature pigs subcutaneously injected once with frozen oncospheres of Taiwan Taenia, Korea Taenia, T. saginata or T. solium emulsified with Freund's complete adjuvant (1.6 x 10(4)/0.4 ml) were challenged orally with 1.6 x 10(4) viable eggs of Taiwan Taenia 41 days later, they all showed strong resistance compared with pigs vaccinated with T. solium. Most pigs (5/8) of the former 3 groups harboured no cysticerci. The number of cysticerci was 5.5 +/- 9.1 (mean +/- S.D.), whereas pigs of the T. solium group and control group harboured 160 +/- 30.1 and 661 +/- 637.2 cysticerci, respectively. All cysticerci recovered from vaccinated pigs and most cysticerci in control pigs were degenerated or calcified at 36-55 days after oral egg challenge. These results strongly suggest that oncospheres of Taiwan Taenia and Korea Taenia are very similar to T. saginata in their immunogenicity in pigs.
authors.affiliation: Department of Parasitology, School of Medicine, National Yangming University, Taipei, Taiwan, Republic of China.
authors.forename: P C
authors.initials: PC
authors.lastname: Fan
authors.forename: W C
authors.initials: WC
authors.lastname: Chung
authors.forename: K S
authors.initials: KS
authors.lastname: Eom
authors.forename: A
authors.initials: A
authors.lastname: Ito
mesh_terms: D000818:Animals; D003551:Cysticercosis / Q000276:immunology / Q000469:parasitology / Q000517:prevention & control / Q000662:veterinary*; D003552:Cysticercus / Q000276:immunology*; D007723:Korea; D010063:Ovum / Q000276:immunology; D013552:Swine; D013553:Swine Diseases / Q000276:immunology / Q000469:parasitology / Q000517:prevention & control*; D013556:Swine, Miniature; D013621:Taenia / Q000276:immunology*; D013624:Taiwan; D014611:Vaccination / Q000662:veterinary*