title: Loss of vision alone may result in seesaw nystagmus.
abstract: A patient is described who developed seesaw nystagmus (SSN) associated with progressive severe vision loss due to cone-rod dystrophy. She was otherwise neurologically normal, and findings on magnetic resonance imaging of the brain were normal, including optic chiasm, meso-diencephalic junction, and brainstem. The literature is reviewed on neurologically normal patients with SSN and ocular vision loss, and the hypothesis is presented that SSN may become manifest as a result of vision loss alone, even in patients with chiasmal lesions, without disruption of central ocular motility pathways.
authors.affiliation: Ophthalmology Service, Madigan Army Medical Center, Tacoma, Washington, USA.
authors.forename: E F
authors.initials: EF
authors.lastname: May
authors.forename: A R
authors.initials: AR
authors.lastname: Truxal
mesh_terms: D000328:Adult; D004585:Electrooculography; D005133:Eye Movements; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009759:Nystagmus, Pathologic / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D010786:Photoreceptor Cells / Q000473:pathology; D012164:Retinal Diseases / Q000150:complications* / Q000175:diagnosis; D014786:Vision Disorders / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology