title: Antimicrobial susceptibilities and capsular types of invasive Streptococcus pneumoniae isolated in children in Mexico City.
abstract: As part of the Sistema Regional de Vacunas (SIREVA) initiative, we conducted a surveillance study to determine the relative prevalence of capsular types of Streptococcus pneumoniae and antimicrobial susceptibility of invasive isolates in children less than 5 years old. We collected 220 isolates and found 33 of the 90 known types, with type 23F as the most common followed by types 6A+B, 14, 19F, and 19A. High penicillin resistance was found in 49 strains (22.2%), 31 belonging to type 23F. Twenty-nine (13.1%) were resistant to erythromycin, 95 (43.1%) were resistant to chloramphenicol, and 24 (10.9%) were resistant to cefotaxime. No strains were resistant to vancomycin.
authors.affiliation: Instituto Nacional de Salud Publica, Cuernavaca, Morelos, México.
authors.forename: G
authors.initials: G
authors.lastname: Echániz-Aviles
authors.forename: M E
authors.initials: ME
authors.lastname: Velázquez-Meza
authors.forename: M N
authors.initials: MN
authors.lastname: Carnalla-Barajas
authors.forename: A
authors.initials: A
authors.lastname: Soto-Noguerón
authors.forename: F
authors.initials: F
authors.lastname: Solórzano-Santos
authors.forename: A
authors.initials: A
authors.lastname: Pérez Miravete
authors.forename: R
authors.initials: R
authors.lastname: Gatica-Marquina
authors.forename: J L
authors.initials: JL
authors.lastname: di Fabio
mesh_terms: D002648:Child; D002675:Child, Preschool; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008826:Microbial Sensitivity Tests; D011159:Population Surveillance; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification / Q000187:drug effects* / Q000302:isolation & purification