title: Complications following butane inhalation and flash fire.
abstract: Solvent inhalation is a well-documented form of drug abuse that can cause euphoria and hallucinations. Sudden death involving a volatile substance is most commonly caused by cardiac arrythmias, asphyxia, direct drug effects, and trauma. The victim in this paper suffered superficial partial thickness (12% total body surface area) burns from a flash fire that occurred when lighting a match after inhaling butane in an enclosed vehicle. The victim was admitted to the hospital for 2 days of observation but did not develop any respiratory symptoms under 2 days following her release. The victim died during her readmission, 9 days after the flash fire. Postmortem examination showed extensive epithelial injury from the upper airway and trachea to the terminal bronchioles, most likely due in part to both the initial inhalation injury and the resulting adult respiratory distress syndrome (ARDS) and staphylococcal infection. Many victims with superficial burn injuries may not seek medical attention owing to either embarrassment or fear of legal prosecution. Even those who do seek medical assistance may not reveal solvent abuse as the cause of their injuries. It is possible that delayed death may occur at home following volatile substance abuse but may remain unrecognized even with a thorough scene investigation.
authors.affiliation: Department of Pathology, University of North Carolina Chapel Hill, USA.
authors.forename: B M
authors.initials: BM
authors.lastname: Huston
authors.forename: K R
authors.initials: KR
authors.lastname: Lamm
mesh_terms: D000293:Adolescent; D002059:Burns, Inhalation / Q000150:complications* / Q000473:pathology; D002073:Butanes; D017809:Fatal Outcome; D005260:Female; D005390:Fires; D006801:Humans; D012128:Respiratory Distress Syndrome / Q000209:etiology / Q000473:pathology; D012772:Shock, Septic / Q000209:etiology* / Q000473:pathology; D013203:Staphylococcal Infections / Q000473:pathology; D019966:Substance-Related Disorders
chemical_list: D002073:Butanes; C046888:butane