[Half-life of blood PSA after radical prostatectomy. Correlations with pathological stage and clinical course of the disease].
PSA half-life was calculated in 37 patients after radical prostatectomy to identify earlier patients with residual disease. The half-life calculated in patients potentially "cured" with absolute PSA values inferior to 0.5 ng/ml after 28 days, was significantly different (P = 0.0008) from the group of patients "uncured" (PSA > 1.0 ng/ml) and from those ones that, despite of detectable PSA level, had evidence of recurrence in the following follow-up. In comparison with the absolute value, the PSA half-life is able to define in the group of patients potentially "cured" those who could have a recurrence in the future.
Di Federico
G
G
Clinica Urologicam, Università G. D'Annunzio, Chieti.
Zezza
A
A
Nicolai
M
M
Lombardi
G
G
Cipollone
G
G
Iantorno
R
R
Boni
R
R
Tenaglia
R
R
D000230:Adenocarcinoma / Q000097:blood* / Q000473:pathology / Q000601:surgery*; D000368:Aged; D005500:Follow-Up Studies; D006207:Half-Life; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D017430:Prostate-Specific Antigen / Q000097:blood*; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000097:blood* / Q000473:pathology / Q000601:surgery*
D017430:Prostate-Specific Antigen