Disruptive behavior and actigraphic measures in home-dwelling patients with Alzheimer's disease: preliminary report.
The purpose of this preliminary report was to explore overall level and diurnal patterning of caregiver reports of abnormal behavior and to explore relationships with actigraphic measures of sleep/wake activity in Alzheimer's disease (AD) patients. Our primary behavioral measure was the Time-based Behavioral Disturbance Questionnaire (TBDQ). The overall score on this measure was shown to have adequate test-retest reliability and convergent validity with another behavioral measure. Significant correlations were obtained between the TBDQ overall score and actigraphically scored sleep efficiency (r = -.35, P < .05) and wake after sleep onset (r = .43, P < .01) in 41 subjects. The data suggest a moderate relationship between actigraphic measures of sleep/wake and disturbed behavior in home-dwelling AD patients.
Friedman
L
L
Department of Veterans Affairs Medical Center, California, USA.
Kraemer
H C
HC
Zarcone
V
V
Sage
S
S
Wicks
D
D
Bliwise
D L
DL
Sheikh
J
J
Tinklenberg
J
J
Yesavage
J A
JA
D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000523:psychology; D017028:Caregivers / Q000523:psychology; D002940:Circadian Rhythm; D017281:Cost of Illness; D005260:Female; D006701:Home Nursing / Q000523:psychology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D011595:Psychomotor Agitation / Q000175:diagnosis* / Q000523:psychology; D012920:Social Behavior Disorders / Q000175:diagnosis* / Q000523:psychology