title: A system to generate simultaneous forced oscillation and continuous positive airway pressure.
abstract: Assessment of airway obstruction in patients with obstructive sleep apnoea (OSA) subjected to continuous positive airway pressure (CPAP) may be carried out using the forced oscillation technique (FOT). To facilitate routine application of forced oscillation (FO) in sleep studies, our aim was to design a system capable of generating CPAP and applying FOT simultaneously. We constructed a prototype CPAP + FO generator by connecting a specially designed electromagnetic valve in parallel with a conventional blower. The capacity of the prototype to generate forced oscillation (5 Hz +/- 1 hPa) was tested by connecting it to a model simulating spontaneous breathing. The response of the prototype for target CPAPs of 5, 10 and 15 hPa and imposed sinusoidal breathing with peak flow up to 0.75 L x s(-1) was excellent when compared with that reported for commercially available CPAP generators. The applicability of the prototype was tested by applying it to assess airway obstruction in four patients with OSA during sleep. We conclude that the generator designed is able to apply continuous positive airway pressure and forced oscillation simultaneously. The system could be useful for automatic and noninvasive assessment of airway obstruction in patients with obstructive sleep apnoea subjected to continuous positive airway pressure. Future development of the generator may be helpful in implementing a set-up for automatic titration of continuous positive airway pressure.
authors.affiliation: Lab. Biofísica i Bioenginyeria, Facultat de Medicina, Universitat de Barcelona, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Farré
authors.forename: M
authors.initials: M
authors.lastname: Rotger
authors.forename: J M
authors.initials: JM
authors.lastname: Montserrat
authors.forename: D
authors.initials: D
authors.lastname: Navajas
mesh_terms: D000403:Airway Resistance; D004867:Equipment Design; D006801:Humans; D008297:Male; D011175:Positive-Pressure Respiration / Q000295:instrumentation; D012129:Respiratory Function Tests / Q000295:instrumentation*; D012891:Sleep Apnea Syndromes / Q000503:physiopathology* / Q000628:therapy*