title: Health-related quality of life in older patients with schizophrenia and other psychoses: relationships among psychosocial and psychiatric factors.
abstract: OBJECTIVE
  Few multivariate studies relating psychosocial factors to symptoms of psychosis among older patients exist. We assessed environmental stressors, satisfaction with emotional support, coping responses and psychiatric symptoms, and sought to relate these factors to quality of well-being among older patients with schizophrenia and other psychoses.
  
  
  METHODS
  Subjects were 70 psychosis patients with a mean age of 58. Predictors included measures of stressors (number of negative life events), satisfaction with emotional support, coping responses, positive and negative symptoms, depressive symptoms, social adjustment and a general quality of well-being (QWB) score.
  
  
  RESULTS
  A conceptual model was tested and modified using path analytic techniques. Preliminary analyses suggested that psychosocial environment (life events, coping and emotional support) was primarily a product of psychiatric symptoms. Therefore, psychiatric symptoms preceded psychosocial environment variables in the proposed model. Further results suggested that depression mediated all of the effects of psychotic symptoms on social maladjustment, but not all of their effects on well-being.
  
  
  CONCLUSIONS
  In older patients with schizophrenia and other psychoses, health-related quality of well-being is influenced by symptoms of psychoses, psychosocial factors and social maladjustment.
authors.affiliation: Department of Psychiatry, University of California, San Diego, La Jolla 92093-0680, USA.
authors.forename: T L
authors.initials: TL
authors.lastname: Patterson
authors.forename: W
authors.initials: W
authors.lastname: Shaw
authors.forename: S J
authors.initials: SJ
authors.lastname: Semple
authors.forename: S
authors.initials: S
authors.lastname: Moscona
authors.forename: M J
authors.initials: MJ
authors.lastname: Harris
authors.forename: R M
authors.initials: RM
authors.lastname: Kaplan
authors.forename: I
authors.initials: I
authors.lastname: Grant
authors.forename: D V
authors.initials: DV
authors.lastname: Jeste
mesh_terms: D000223:Adaptation, Psychological; D015984:Causality; D016009:Chi-Square Distribution; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D008960:Models, Psychological; D011618:Psychotic Disorders / Q000150:complications / Q000523:psychology*; D011788:Quality of Life; D012044:Regression Analysis; D012494:Sampling Studies; D012565:Schizophrenic Psychology; D012720:Severity of Illness Index; D012917:Social Adjustment; D012944:Social Support; D013315:Stress, Psychological / Q000150:complications