title: Biochemical and pharmacologic rationale for the development of a synthetic heparin pentasaccharide.
authors.affiliation: Department of Pathology, Loyola University Medical Center, Maywood, Illinois 60153, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Walenga
authors.forename: W P
authors.initials: WP
authors.lastname: Jeske
authors.forename: L
authors.initials: L
authors.lastname: Bara
authors.forename: M M
authors.initials: MM
authors.lastname: Samama
authors.forename: J
authors.initials: J
authors.lastname: Fareed
mesh_terms: D000818:Animals; D000925:Anticoagulants / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000990:Antithrombin III / Q000378:metabolism; D001665:Binding Sites; D001792:Blood Platelets / Q000187:drug effects; D002240:Carbohydrate Sequence; D065427:Factor Xa Inhibitors; D006470:Hemorrhage / Q000139:chemically induced; D006493:Heparin / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D066298:In Vitro Techniques; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009844:Oligosaccharides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D013927:Thrombosis / Q000517:prevention & control
chemical_list: D000925:Anticoagulants; D065427:Factor Xa Inhibitors; D009844:Oligosaccharides; C049714:IC 831423; D000990:Antithrombin III; D006493:Heparin