title: Synthesis of cis- and trans- 2-arylmethylcycloalkylamines: potential dopaminergic agents.
abstract: This paper reports the synthesis and the study of a few new diastereomeric arylmethylcycloalkylamines, tested as potential dopamine receptor active agents. New procedures for the stereospecific synthesis of the arylmethylcycloalkylamines were successfully experimented. All the considered compounds did not show any appreciable dopamine receptor activity.
authors.affiliation: Dipartimento Farmaco Chimico Tecnologico, Università di Cagliari.
authors.forename: C
authors.initials: C
authors.lastname: Anchisi
authors.forename: B M
authors.initials: BM
authors.lastname: Baroli
authors.forename: A M
authors.initials: AM
authors.lastname: Fadda
authors.forename: A M
authors.initials: AM
authors.lastname: Maccioni
authors.forename: E
authors.initials: E
authors.lastname: Maccioni
authors.forename: C
authors.initials: C
authors.lastname: Sinico
mesh_terms: D000588:Amines / Q000138:chemical synthesis* / Q000494:pharmacology; D000818:Animals; D003516:Cycloparaffins / Q000138:chemical synthesis* / Q000494:pharmacology; D015259:Dopamine Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051381:Rats; D011954:Receptors, Dopamine / Q000187:drug effects; D013055:Spectrophotometry, Infrared
chemical_list: D000588:Amines; D003516:Cycloparaffins; D015259:Dopamine Agents; D011954:Receptors, Dopamine