Aminoguanidine inhibits the generation of nitric oxide in vitro and prolongs islet xenograft survival in rats.
Behboo
R
R
Clinica Chirurgica I, University of Padua, Italy.
Ricordi
C
C
Lumachi
F
F
Tedeschi
U
U
Urso
E
E
Cillo
U
U
Bonariol
L
L
Favia
G
G
D'Amico
D F
DF
D000704:Analysis of Variance; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000601:surgery; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005720:Gamma Rays; D006085:Graft Survival / Q000187:drug effects*; D006146:Guanidines / Q000494:pharmacology*; D006801:Humans; D007515:Islets of Langerhans / Q000166:cytology / Q000502:physiology* / Q000528:radiation effects; D016381:Islets of Langerhans Transplantation / Q000502:physiology*; D008297:Male; D009569:Nitric Oxide / Q000378:metabolism*; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors / Q000096:biosynthesis*; D016133:Polymerase Chain Reaction; D051381:Rats; D017208:Rats, Wistar; D014158:Transcription, Genetic / Q000187:drug effects; D014183:Transplantation, Heterologous / Q000502:physiology*
D004791:Enzyme Inhibitors; D006146:Guanidines; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase; C004479:pimagedine