title: A case of chrysiasis.
abstract: Chrysiasis and chrysoderma are terms used to describe permanent pigmentation of the skin due to the parenteral administration of gold salts. A case of chrysiasis, including a photomicrograph of the characteristic orange-red birefringence of gold in tissue when viewed under cross-polarized light, is presented. A review of the literature on the pathogenesis of the pigmentation seen in this disorder is also presented.
authors.affiliation: Department of Dermatology, National Naval Medical Center, Bethesda, Maryland, USA.
authors.forename: M L
authors.initials: ML
authors.lastname: Miller
authors.forename: R R
authors.initials: RR
authors.lastname: Harford
authors.forename: J K
authors.initials: JK
authors.lastname: Yeager
authors.forename: F
authors.initials: F
authors.lastname: Johnson
mesh_terms: D000368:Aged; D018501:Antirheumatic Agents / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy; D001718:Birefringence; D005260:Female; D006046:Gold / Q000032:analysis; D006801:Humans; D008855:Microscopy, Electron, Scanning; D010859:Pigmentation Disorders / Q000139:chemically induced* / Q000473:pathology; D012867:Skin / Q000737:chemistry / Q000473:pathology*; D013052:Spectrometry, X-Ray Emission
chemical_list: D018501:Antirheumatic Agents; D006046:Gold