Gap junctions: getting the message through.
Connexin proteins make intercellular channels - gap junctions - which provide a direct pathway for cell-cell signaling in vertebrates. Studies of mice lacking connexin genes have demonstrated the need for intercellular transfer of messenger molecules and are uncovering the specific functions of each connexin.
Nicholson
S M
SM
Institut Pasteur, 25 rue du Docteur Roux, F-75724, Paris, CEDEX 15, France. smn@pasteur.fr
Bruzzone
R
R
D000818:Animals; D002450:Cell Communication / Q000502:physiology*; D017630:Connexins / Q000502:physiology*; D005260:Female; D017629:Gap Junctions / Q000502:physiology*; D051379:Mice; D018345:Mice, Knockout; D009866:Oogenesis / Q000502:physiology; D010060:Ovulation / Q000502:physiology; D019076:Transgenes
D017630:Connexins