title: Role of the heart surgeon in the emergency treatment of diuretic resistant edema in grades III-IV heart failure.
abstract: Acute or chronic valvular diseases, acute myocardial infarction and its complications, dilated cardiomyopathies, all may became the cause of heart failure leading to different degrees of cardiogenic edema. Today cardiac failure is treated from its the early stage by medical and/or surgical therapy. Thereafter, in a small population of patients, heart failure may became unresponsive to any kind of standard medical treatment. Conventional surgical procedures are often inadequate and carry a high risk of perioperative mortality. This study analyzes the outcome of 139 patients with end-stage cardiomyopathy who underwent heart transplantation between January 1988 and October 1996. We found that patients transplanted while on severe decompensation are at a higher perioperative mortality due to irreversible multi-organ failure. The study also suggests that the implantation of a left ventricle assist device as a bridge to transplantation is a promising maneuver for the most severe patients.
authors.affiliation: Department of Cardiac Surgery, Second University of Naples Hospital V. Monaldi, Italy.
authors.forename: F
authors.initials: F
authors.lastname: de Vivo
authors.forename: L S
authors.initials: LS
authors.lastname: DeSanto
authors.forename: C
authors.initials: C
authors.lastname: Maiello
authors.forename: R
authors.initials: R
authors.lastname: Trunfio
authors.forename: C
authors.initials: C
authors.lastname: Marra
authors.forename: M
authors.initials: M
authors.lastname: De Feo
authors.forename: G
authors.initials: G
authors.lastname: Damiani
authors.forename: N
authors.initials: N
authors.lastname: Galdieri
authors.forename: M
authors.initials: M
authors.lastname: Cotrufo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D006348:Cardiac Surgical Procedures; D002648:Child; D004232:Diuretics / Q000627:therapeutic use*; D004351:Drug Resistance; D004489:Edema, Cardiac / Q000188:drug therapy*; D004630:Emergencies; D005260:Female; D016027:Heart Transplantation; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D004232:Diuretics