title: Synovial sarcoma of the neck.
abstract: Primary synovial sarcoma of the head and neck region is a rare tumor. This report describes seven cases of primary synovial sarcomas, of which two were in the parapharyngeal region, two in the supraclavicular region, and one each in the hypopharynx, sternocleidomastoid and submandibular regions. Clinical presentations, radiological findings, histopathology and management are reviewed. All patients received multimodal therapy using aggressive surgery, radiotherapy and chemotherapy. Five of the patients are alive and disease free after 24-108 months of follow-up. Achievement of locoregional control appears to be the hallmark of successful therapy.
authors.affiliation: Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bangalore, India.
authors.forename: D C
authors.initials: DC
authors.lastname: Doval
authors.forename: V
authors.initials: V
authors.lastname: Kannan
authors.forename: G
authors.initials: G
authors.lastname: Mukherjee
authors.forename: A M
authors.initials: AM
authors.lastname: Shenoy
authors.forename: M H
authors.initials: MH
authors.lastname: Shariff
authors.forename: P P
authors.initials: PP
authors.lastname: Bapsy
mesh_terms: D000293:Adolescent; D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D010039:Otorhinolaryngologic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D013584:Sarcoma, Synovial / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy; D015996:Survival Rate; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor