title: FDG SPECT in the assessment of myocardial viability. Comparison with dobutamine echo.
abstract: The use of 18F-fluorodeoxyglucose (FDG) imaging with single photon emission computed tomography (SPECT) has been introduced recently to assess myocardial viability. Several centres have now gained experience with cardiac FDG SPECT imaging, and this report is a summary of the currently available FDG SPECT data. Three studies have compared FDG SPECT with FDG positron emission tomography and demonstrated good agreement between them. Initial results in patients undergoing revascularization suggest that FDG SPECT can predict improvement in contractile function after revascularization. Although the initial results are promising, larger studies are needed to determine the precise role of FDG SPECT in the assessment of myocardial viability.
authors.affiliation: Department of Cardiology, University Hospital Leiden, The Netherlands.
authors.forename: J J
authors.initials: JJ
authors.lastname: Bax
authors.forename: R
authors.initials: R
authors.lastname: Valkema
authors.forename: F C
authors.initials: FC
authors.lastname: Visser
authors.forename: A
authors.initials: A
authors.lastname: van Lingen
authors.forename: J H
authors.initials: JH
authors.lastname: Cornel
authors.forename: D
authors.initials: D
authors.lastname: Poldermans
authors.forename: R
authors.initials: R
authors.lastname: Rambaldi
authors.forename: E P
authors.initials: EP
authors.lastname: Krenning
authors.forename: P M
authors.initials: PM
authors.lastname: Fioretti
mesh_terms: D002316:Cardiotonic Agents; D003847:Deoxyglucose / Q000031:analogs & derivatives* / Q000494:pharmacology; D004280:Dobutamine; D004452:Echocardiography / Q000379:methods*; D005080:Exercise Test / Q000379:methods; D019788:Fluorodeoxyglucose F18; D005947:Glucose / Q000378:metabolism; D006801:Humans; D000960:Hypolipidemic Agents / Q000008:administration & dosage; D009200:Myocardial Contraction / Q000187:drug effects; D009203:Myocardial Infarction / Q000000981:diagnostic imaging*; D015425:Myocardial Reperfusion; D009206:Myocardium / Q000378:metabolism; D011237:Predictive Value of Tests; D011719:Pyrazines / Q000008:administration & dosage; D019275:Radiopharmaceuticals / Q000494:pharmacology; D012680:Sensitivity and Specificity; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*
chemical_list: D002316:Cardiotonic Agents; D000960:Hypolipidemic Agents; D011719:Pyrazines; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D004280:Dobutamine; D003847:Deoxyglucose; D005947:Glucose; C027696:acipimox