title: Determination of genotypes of hepatitis C virus in Venezuela by restriction fragment length polymorphism.
abstract: Hepatitis C virus genotypes in Venezuela were analyzed by restriction fragment length polymorphism in the 5' noncoding region. The absence of BstUI digestion was found to be a useful marker for genotype 2 specimens. From 122 serum samples, 66, 20, and 2.5% were classified as genotypes 1, 2, and 3, respectively; 0.8% were classified as genotype 4; and 10% appeared to be mixed infections.
authors.affiliation: Laboratorio Biología de Virus, CMBC, IVIC, Caracas, Venezuela. fpujol@pasteur.ivic.ve
authors.forename: F H
authors.initials: FH
authors.lastname: Pujol
authors.forename: C L
authors.initials: CL
authors.lastname: Loureiro
authors.forename: M
authors.initials: M
authors.lastname: Devesa
authors.forename: L
authors.initials: L
authors.lastname: Blitz
authors.forename: K
authors.initials: K
authors.lastname: Parra
authors.forename: S
authors.initials: S
authors.lastname: Beker
authors.forename: F
authors.initials: F
authors.lastname: Liprandi
mesh_terms: D005814:Genes, Viral / Q000235:genetics; D005838:Genotype; D016174:Hepacivirus / Q000235:genetics* / Q000302:isolation & purification; D006526:Hepatitis C / Q000453:epidemiology / Q000821:virology*; D006801:Humans; D008969:Molecular Sequence Data; D014687:Venezuela / Q000453:epidemiology