title: Association of plasma renin activity and echocardiographic left ventricular hypertrophy with frequency of new coronary events and new atherothrombotic brain infarction in older persons with systemic hypertension.
abstract: In older hypertensive persons, male gender, prior coronary artery disease, prior atherothrombotic brain infarction (ABI), and echocardiographic left ventricular (LV) hypertrophy are independent risk factors for new coronary events; age, prior ABI, and echocardiographic LV hypertrophy are independent risk factors for new ABI. The data suggest that high plasma renin activity in hypertensive older persons is associated with a high risk of new coronary events and of new ABI through its association with echocardiographic LV hypertrophy.
authors.affiliation: Hebrew Hospital Home, Bronx, New York 10475, USA.
authors.forename: W S
authors.initials: WS
authors.lastname: Aronow
authors.forename: C
authors.initials: C
authors.lastname: Ahn
authors.forename: I
authors.initials: I
authors.lastname: Kronzon
authors.forename: H
authors.initials: H
authors.lastname: Gutstein
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002544:Cerebral Infarction / Q000097:blood* / Q000150:complications* / Q000000981:diagnostic imaging; D003327:Coronary Disease / Q000097:blood* / Q000150:complications* / Q000000981:diagnostic imaging; D004452:Echocardiography; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000150:complications* / Q000000981:diagnostic imaging; D017379:Hypertrophy, Left Ventricular / Q000097:blood* / Q000150:complications / Q000000981:diagnostic imaging*; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D012083:Renin / Q000097:blood*
chemical_list: D012083:Renin