[The phospholipid composition of the liver and the glycolipid spectrum of the brain in rats administered cyanamide].
The effect of cyanamide on the liver phospholipids and brain glycolipids was studied (on rats). It was found that cyanamide (60 mg/kg, intraperitoneally) increased the amount of liver lysophosphatidylcholine, sphingomyelin, cardiolipin and decreased phosphatidylcholine and phosphatidylethanolamine. Similar but more pronounced alterations of liver phospholipids were found after ethanol administration 91 g/kg, 20% solution intraperitoneally) under the influence of cyanamide. After cyanamide and its combination with alcohol brain concentrations of sulfatides I, II as well as cerebrosides l, II and III decreased.
Selevich
M I
MI
Lepevich
V V
VV
D000818:Animals; D001921:Brain / Q000187:drug effects*; D001923:Brain Chemistry / Q000187:drug effects; D003484:Cyanamide / Q000494:pharmacology*; D004347:Drug Interactions; D000431:Ethanol / Q000494:pharmacology; D006017:Glycolipids / Q000032:analysis*; D008099:Liver / Q000737:chemistry / Q000187:drug effects*; D008297:Male; D010743:Phospholipids / Q000032:analysis*; D051381:Rats
D006017:Glycolipids; D010743:Phospholipids; D000431:Ethanol; D003484:Cyanamide