A case of estrogen dermatitis.
A 29-year-old Korean woman had erythematous papular patches on her face for six months. The eruptions recurred in a cyclic fashion along with her menstruation. The patient responded positively to an intradermal skin test for estrogen and showed marked improvement with the antiestrogen drug, Tamoxifen. We concluded that sensitivity to her own estrogen caused this dermatitis, that an intradermal skin test with progesterone and estrogen should be carried out routinely in patients with cyclic premenstrual flares, and that tamoxifen can be used as a specific therapy. To the best of our knowledge, this woman is the first patient with estrogen dermatitis reported in Korea.
Kim
K H
KH
Department of Dermatology, Gyeongsang National University Hospital, Korea.
Yoon
T J
TJ
Oh
C W
CW
Kim
T H
TH
D000328:Adult; D001706:Biopsy; D003875:Drug Eruptions / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D004965:Estrogen Antagonists / Q000627:therapeutic use; D004967:Estrogens / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007428:Intradermal Tests; D012008:Recurrence; D013629:Tamoxifen / Q000627:therapeutic use
D004965:Estrogen Antagonists; D004967:Estrogens; D013629:Tamoxifen