Modulation of the autoimmune response in lupus mice by oral administration of attenuated Salmonella typhimurium expressing the IL-2 and TGF-beta genes.
Huggins
M L
ML
University Department of Immunology, United Kingdom.
Huang
F P
FP
Xu
D
D
Lindop
G
G
Stott
D I
DI
D000284:Administration, Oral; D000818:Animals; D015551:Autoimmunity / Q000187:drug effects*; D015316:Genetic Therapy; D005822:Genetic Vectors; D007376:Interleukin-2 / Q000235:genetics*; D008180:Lupus Erythematosus, Systemic / Q000276:immunology* / Q000628:therapy; D051379:Mice; D019463:Mice, Inbred MRL lpr; D012486:Salmonella typhimurium; D013601:T-Lymphocytes / Q000166:cytology / Q000187:drug effects; D014162:Transfection; D016212:Transforming Growth Factor beta / Q000235:genetics*
D007376:Interleukin-2; D016212:Transforming Growth Factor beta