title: Evidence for the polyp-cancer sequence in gallbladder cancer.
abstract: We report a patient with symptomatic biliary disease and who was diagnosed by ultrasound to have a large polypoid gallbladder lesion. Histopathology revealed adenoma in combination with carcinoma in situ. The evidence for the adenoma-carcinoma sequence in gallbladder cancer and diagnostic and therapeutic implications are discussed.
authors.affiliation: Department of Surgery, St. Vincent's Hospital, Dublin.
authors.forename: J
authors.initials: J
authors.lastname: Harbison
authors.forename: J V
authors.initials: JV
authors.lastname: Reynolds
authors.forename: K
authors.initials: K
authors.lastname: Sheahan
authors.forename: R G
authors.initials: RG
authors.lastname: Gibney
authors.forename: J M
authors.initials: JM
authors.lastname: Hyland
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology*; D018256:Adenomatous Polyps / Q000000981:diagnostic imaging / Q000473:pathology*; D000328:Adult; D002278:Carcinoma in Situ / Q000000981:diagnostic imaging / Q000473:pathology*; D005704:Gallbladder / Q000473:pathology; D005706:Gallbladder Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008297:Male; D014463:Ultrasonography