Soluble factor(s) alone produced by primary porcine microvascular endothelial cells support the proliferation and differentiation of human CD34+ hematopoietic progenitor cells with a high replating potential.
Davis
T A
TA
Immune Cell Biology Program, Naval Medical Research Institute, Bethesda, Maryland 20889-5067, USA.
Black
A T
AT
Lee
K P
KP
D000818:Animals; D001685:Biological Factors / Q000378:metabolism* / Q000494:pharmacology; D001854:Bone Marrow Cells; D002454:Cell Differentiation / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D017077:Culture Media, Conditioned; D004730:Endothelium, Vascular / Q000166:cytology / Q000502:physiology*; D004921:Erythropoietin / Q000494:pharmacology; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000494:pharmacology; D006133:Growth Substances / Q000494:pharmacology*; D006410:Hematopoiesis; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000187:drug effects; D006801:Humans; D007377:Interleukin-3 / Q000494:pharmacology; D008565:Membrane Proteins / Q000494:pharmacology; D008833:Microcirculation; D019089:Stem Cell Factor / Q000494:pharmacology; D013552:Swine
D001685:Biological Factors; D017077:Culture Media, Conditioned; D006133:Growth Substances; D007377:Interleukin-3; D008565:Membrane Proteins; D019089:Stem Cell Factor; C084881:flt3 ligand protein; D004921:Erythropoietin; D016178:Granulocyte-Macrophage Colony-Stimulating Factor