Wegener's presenting as submandibular swelling.
We describe a patient in whom bilateral swelling of submandibular glands was the initial manifestation of limited Wegener's disease. The diagnosis was based on positive anti-neutrophil cytoplasmic antibody [C-ANCA], dense inflammatory infiltrate predominantly of lymphocytes in submandibular glands, presence of non-caseating ill-formed granulomas in transbronchial biopsy and resolution of symptoms following immuno-suppressive treatment.
Singh
S
S
Department of Internal Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Kaura
D
D
Kumari
S
S
Gupta
D
D
Dey
P
P
Suri
S
S
D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis; D001706:Biopsy; D001999:Bronchoscopy; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012466:Salivary Gland Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D013363:Submandibular Gland / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed
D019268:Antibodies, Antineutrophil Cytoplasmic; D007166:Immunosuppressive Agents