[An experimental study of the pharmacokinetics of a new pediatric drug form--Paravit tablets].
A comparative study of Paravit and paracetamol pharmacokinetics is carried out on impuberal rabbits. It has been shown that ascortic acid present in Paravit enhances the bioavailability of paracetamol. The relative bioequivalence of Paravit is found to be 136.7%.
Shapovalova
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VA
D000082:Acetaminophen / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000493:pharmacokinetics*; D000818:Animals; D001205:Ascorbic Acid / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D001682:Biological Availability; D004338:Drug Combinations; D005260:Female; D008297:Male; D011817:Rabbits; D013607:Tablets; D013997:Time Factors
D018712:Analgesics, Non-Narcotic; D004338:Drug Combinations; D013607:Tablets; D000082:Acetaminophen; D001205:Ascorbic Acid