title: Clinical use of acid steatocrit.
abstract: Malabsorption of fat is an important gastrointestinal cause of malnutrition and growth retardation in childhood. The gold standard for the evaluation of fat malabsorption is the faecal fat balance method. The acid steatocrit method has recently been introduced as a simple method to evaluate faecal fat. The present study was aimed at evaluating the acid steatocrit in clinical practice. Faecal fat excretion and acid steatocrit results were determined in 42 children, half with and half without fat malabsorption. Acid steatocrit results correlated significantly with both faecal fat excretion (p < 0.01) and faecal fat concentration (p < 0.001). Sensitivity and specificity of the acid steatocrit for the diagnosis of malabsorption were 90% and 100%, respectively. We consider the acid steatocrit method useful for the screening and monitoring of patients with steatorrhoea.
authors.affiliation: Department of Paediatrics, University Hospital Maastricht, The Netherlands.
authors.forename: A
authors.initials: A
authors.lastname: Van den Neucker
authors.forename: N
authors.initials: N
authors.lastname: Pestel
authors.forename: T M
authors.initials: TM
authors.lastname: Tran
authors.forename: P P
authors.initials: PP
authors.lastname: Forget
authors.forename: H J
authors.initials: HJ
authors.lastname: Veeze
authors.forename: J
authors.initials: J
authors.lastname: Bouquet
authors.forename: M
authors.initials: M
authors.lastname: Sinaasappel
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002446:Celiac Disease / Q000175:diagnosis* / Q000209:etiology / Q000378:metabolism; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications; D004041:Dietary Fats / Q000032:analysis* / Q000378:metabolism; D005243:Feces / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D008403:Mass Screening; D010472:Perchlorates; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D017186:Titrimetry
chemical_list: D004041:Dietary Fats; D010472:Perchlorates