[Adrenergic receptors and alpha 2 agonists--1) Molecular biological study of adrenoceptors].
Molecular biological studies have established classification of adrenergic receptors 40 years after Prof Ahlquist first classified them into alpha and beta. They are now classified into 9 subtypes consisting of 400 to 480 amino acids. They belong to a super-family of G-protein coupled receptors. Based on the amino acid sequence, the topography of adrenoceptors is depicted as a snake model twisting itself back and forth through the membrane 7 times.
Mizobe
T
T
Department of Anesthesiology, Kyoto Prefectural University of Medicine.
D000818:Animals; D019204:GTP-Binding Proteins / Q000378:metabolism; D006801:Humans; D017433:Protein Structure, Secondary; D011941:Receptors, Adrenergic / Q000737:chemistry* / Q000145:classification
D011941:Receptors, Adrenergic; D019204:GTP-Binding Proteins