Adherence of Mycoplasma gallisepticum involves variable surface membrane proteins.
Adherence of Mycoplasma gallisepticum to erythrocytes was examined by colony immunoblotting, detergent phase fractionation, trypsin treatment, comparison of protein profiles, and comparison of erythrocyte-bound mycoplasma protein fractions of hemadsorption-positive and -negative mutants. The binding of M. gallisepticum to chicken or human erythrocytes was found to be mediated via surface-exposed membrane proteins undergoing high-frequency phase variation.
Athamna
A
A
Department of Membrane and Ultrastructure Research, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
Rosengarten
R
R
Levisohn
S
S
Kahane
I
I
Yogev
D
D
D000818:Animals; D001422:Bacterial Adhesion; D001426:Bacterial Proteins / Q000502:physiology*; D002645:Chickens; D004912:Erythrocytes / Q000382:microbiology; D006801:Humans; D008565:Membrane Proteins / Q000502:physiology*; D051379:Mice; D009174:Mycoplasma / Q000502:physiology*
D001426:Bacterial Proteins; D008565:Membrane Proteins