Medroxyprogesterone acetate reduces the production of cytokines and serotonin involved in anorexia/cachexia and emesis by peripheral blood mononuclear cells of cancer patients.
Mantovani
G
G
Department of Medical Oncology, University of Cagliari, Italy.
Macciò
A
A
Esu
S
S
Lai
P
P
Santona
M C
MC
Massa
E
E
Dessì
D
D
Melis
G
G
Del Giacco
S
S
D000855:Anorexia / Q000097:blood* / Q000209:etiology / Q000276:immunology; D015703:Antigens, CD / Q000096:biosynthesis / Q000097:blood; D002100:Cachexia / Q000097:blood* / Q000209:etiology / Q000276:immunology; D002478:Cells, Cultured; D016207:Cytokines / Q000096:biosynthesis / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D007378:Interleukins / Q000097:blood; D008213:Lymphocyte Activation; D008214:Lymphocytes / Q000187:drug effects* / Q000276:immunology / Q000502:physiology; D017258:Medroxyprogesterone Acetate / Q000494:pharmacology*; D009369:Neoplasms / Q000097:blood / Q000276:immunology / Q000503:physiopathology*; D015375:Receptors, Interleukin-2 / Q000096:biosynthesis; D012701:Serotonin / Q000097:blood*; D014409:Tumor Necrosis Factor-alpha / Q000096:biosynthesis; D014839:Vomiting / Q000097:blood* / Q000209:etiology / Q000276:immunology
D015703:Antigens, CD; D016207:Cytokines; D007378:Interleukins; D015375:Receptors, Interleukin-2; D014409:Tumor Necrosis Factor-alpha; D012701:Serotonin; D017258:Medroxyprogesterone Acetate