title: [Suicidal risk in bipolar disorders].
abstract: Mortality and morbidity are greatly increased in patients with mood disorders, due to suicide, cardiovascular and other diseases. Recent data for bipolar disorders have been released: the suicidal risk is very high in these patients, whereas a long term treatment with lithium brings down morbidity to the rate of general population. There are no data for other mood stabilizers on this subject. Further studies are needed in order to confirm that long term prophylaxy with new compounds (valpromide, carbamazepine, etc.) is also efficacious, concerning this aspect, especially in bipolar II, mixed states and dysphoric mania. There is a dearth of research in the field of the "bipolar spectrum" (soft bipolar pathology).
authors.affiliation: IPSO: Université Victor Segalen, Bordeaux II.
authors.forename: M L
authors.initials: ML
authors.lastname: Bourgeois
authors.forename: H
authors.initials: H
authors.lastname: Verdoux
mesh_terms: D000293:Adolescent; D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy / Q000401:mortality* / Q000523:psychology; D015897:Comorbidity; D003431:Cross-Cultural Comparison; D005260:Female; D006801:Humans; D008094:Lithium / Q000008:administration & dosage; D008297:Male; D012307:Risk Factors; D013405:Suicide / Q000523:psychology / Q000706:statistics & numerical data*; D000092864:Suicide Prevention
chemical_list: D008094:Lithium