title: Diet does not ensure normal development in galactosemia.
abstract: This review deals with the treatment of inherited classical galactosemia by a lactose-free diet. Although, with dietary treatment, there is a remarkable improvement in the acute phase of the disease, the long-term outcome has been disappointing for most patients, especially regarding the central nervous system and ovarian dysfunction in females. There is a need for new approaches to treatment, in combination with diet therapy, that could improve the outcome of patients with galactosemia.
authors.affiliation: Department of Pediatrics, University of Vienna, Austria.
authors.forename: K
authors.initials: K
authors.lastname: Widhalm
authors.forename: B D
authors.initials: BD
authors.lastname: Miranda da Cruz
authors.forename: M
authors.initials: M
authors.lastname: Koch
mesh_terms: D005693:Galactosemias / Q000175:diagnosis / Q000178:diet therapy* / Q000209:etiology; D006801:Humans; D007785:Lactose / Q000008:administration & dosage / Q000009:adverse effects*; D011379:Prognosis
chemical_list: D007785:Lactose