title: [Primary angiosarcoma of the breast. Apropos of 2 cases].
abstract: We report here 2 cases of breast angiosarcoma observed at Centre Val-d' Aurelle of Montpellier over a period of 14 years (1980 to 1994). Based on a review of literature, we analyze the epidemiological, pathological, clinical, diagnostic and treatment aspects of this rare type of breast cancer. The difficulties of histological diagnosis are underlined. Mastectomy is the treatment of reference. Breast angiosarcoma has the worst prognosis of all mammary malignancies, with a mean survival of 24 months. The low histologic grade and an early diagnosis are the most important factors of good prognosis. The benefit of irradiation and chemotherapy as adjuvant therapy remains to be demonstrated.
authors.affiliation: Service de radiothérapie du Centre régional de lutte contre le cancer Val-d' Aurelle, Montpellier, France.
authors.forename: M M
authors.initials: MM
authors.lastname: Melhouf
authors.forename: N
authors.initials: N
authors.lastname: Amrani
authors.forename: J
authors.initials: J
authors.lastname: Simony-Lafontaine
authors.forename: H
authors.initials: H
authors.lastname: Pujol
authors.forename: J B
authors.initials: JB
authors.lastname: Dubois
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D006394:Hemangiosarcoma / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D006801:Humans; D008197:Lymph Node Excision; D008408:Mastectomy; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011379:Prognosis; D011879:Radiotherapy Dosage