Substituted [(4-phenylpiperazinyl)-methyl]benzamides: selective dopamine D4 agonists.
Glase
S A
SA
Department of Chemistry, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, Ann Arbor, Michigan 48105, USA.
Akunne
H C
HC
Georgic
L M
LM
Heffner
T G
TG
MacKenzie
R G
RG
Manley
P J
PJ
Pugsley
T A
TA
Wise
L D
LD
D000818:Animals; D001549:Benzamides / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D016466:CHO Cells; D006224:Cricetinae; D018492:Dopamine Antagonists / Q000494:pharmacology; D006220:Haloperidol / Q000494:pharmacology; D006801:Humans; D015394:Molecular Structure; D010879:Piperazines / Q000138:chemical synthesis* / Q000378:metabolism / Q000494:pharmacology; D017448:Receptors, Dopamine D2 / Q000819:agonists* / Q000235:genetics / Q000378:metabolism; D050638:Receptors, Dopamine D4; D013329:Structure-Activity Relationship; D014162:Transfection
D001549:Benzamides; C493599:DRD4 protein, human; D018492:Dopamine Antagonists; C106584:N-((4-(2-cyanophenyl)piperazinyl)methyl)benzamide; D010879:Piperazines; D017448:Receptors, Dopamine D2; D050638:Receptors, Dopamine D4; D006220:Haloperidol