title: Malignant pleural effusions due to adeno-endocrine-cell carcinoma of the appendix: a case report.
abstract: The cellular features of adeno-endocrine-cell carcinoma of appendiceal origin are presented. The pleural fluid contained metastatic predominantly atypical cells in linear cluster accompanied by numerous mesothelial cells. The cells had small round nuclei, with a slight tendency to molding; nucleoli were absent. The cytologic findings in Papanicolaou-stained smears of the pleural fluid suggested a metastatic small-cell carcinoma of the lung. Subsequently, adeno-endocrine-cell carcinoma of the appendix was demonstrated at autopsy. Reports of such occurrences are few; no study, to the best of our knowledge, has previously documented the cytologic diagnosis in pleural fluid.
authors.affiliation: Department of Cytopathology, Saiseikai Shiga Hospital, Imperial Gift Foundation Inc., Japan.
authors.forename: T K
authors.initials: TK
authors.lastname: Kobayashi
authors.forename: M
authors.initials: M
authors.lastname: Ueda
authors.forename: T
authors.initials: T
authors.lastname: Nishino
authors.forename: T
authors.initials: T
authors.lastname: Tamagaki
authors.forename: S
authors.initials: S
authors.lastname: Watanabe
authors.forename: R
authors.initials: R
authors.lastname: Kushima
mesh_terms: D000230:Adenocarcinoma / Q000737:chemistry / Q000473:pathology*; D000368:Aged; D001063:Appendiceal Neoplasms / Q000737:chemistry / Q000473:pathology*; D015415:Biomarkers / Q000032:analysis; D002276:Carcinoid Tumor / Q000737:chemistry / Q000473:pathology*; D018288:Carcinoma, Small Cell / Q000737:chemistry / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000737:chemistry / Q000473:pathology; D010996:Pleural Effusion / Q000473:pathology*; D012189:Retrospective Studies
chemical_list: D015415:Biomarkers