title: A randomized study comparing retroperitoneal drainage with no drainage after lymphadenectomy in gynecologic malignancies.
abstract: OBJECTIVE
  To evaluate the clinical effectiveness of retroperitoneal drainage following lymphadenectomy in gynecologic surgery.
  
  
  METHODS
  One hundred thirty-seven consecutive patients undergoing systematic lymphadenectomy for gynecologic malignancies were randomized to receive (Group A, 68) or not (Group B, 69) retroperitoneal drainage. The pelvic peritoneum and the paracolic gutters were not sutured after node dissection. Perioperative data and complications were recorded.
  
  
  RESULTS
  Clinical and surgical parameters were comparable in the two groups. Postoperative hospital stay was significantly shorter in Group B (P < 0.001), whereas the complication rate was significantly higher in Group A (P = 0.01). This was mainly due to a significant increase in lymphocyst and lymphocyst-related morbidity. Sonographic monitoring for lymphocyst showed free abdominal fluid in 18% of drained and 36% of not-drained patients (P = 0.03). Symptomatic ascites developed in 2 drained (3%) and 3 not-drained (4%) patients (NS), respectively.
  
  
  CONCLUSIONS
  Prophylactic drainage of the retroperitoneum seems to increase lymphadenectomy-related morbidity and postoperative stay. Therefore, routine drainage following lymphadenectomy seems to be no longer indicated when the retroperitoneum is left open.
authors.affiliation: Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Benedetti-Panici
authors.forename: F
authors.initials: F
authors.lastname: Maneschi
authors.forename: G
authors.initials: G
authors.lastname: Cutillo
authors.forename: G
authors.initials: G
authors.lastname: D'Andrea
authors.forename: V S
authors.initials: VS
authors.lastname: di Palumbo
authors.forename: M
authors.initials: M
authors.lastname: Conte
authors.forename: G
authors.initials: G
authors.lastname: Scambia
authors.forename: S
authors.initials: S
authors.lastname: Mancuso
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004322:Drainage / Q000379:methods; D005260:Female; D006801:Humans; D008197:Lymph Node Excision / Q000009:adverse effects; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000601:surgery*; D011182:Postoperative Care; D011183:Postoperative Complications / Q000453:epidemiology / Q000517:prevention & control; D012187:Retroperitoneal Space; D014594:Uterine Neoplasms / Q000601:surgery*