[Correlation between prostate specific antigen and histopathologic findings in ileum-obturator node dissection].
OBJECTIVE
To determine the correlation between PSA values and the histopathological findings of ileo-obturator node dissection in prostatic cancer.


METHODS
We reviewed the data of 51 patients with clinically localized prostatic carcinoma, submitted to ileo-obturator node dissection before definitive treatment of the tumor. The patients were classified into 4 groups according to their previous PSA values: A < 10 ng/ml, B > 10 and < 20 ng/ml, C > 20 and < 50 ng/ml and D < 50 ng/ml.


RESULTS
Overall 17.6% of the patients had positive lymph nodes; 9.9% of the patients in group A, 15.4% of the patients in group B, 11.1% of those in group C and 41.7% of those in group D had positive nodes. Using 50 ng/ml as the cut-off point, 10% of those with PSA < 50 ng/ml had positive nodes vs 42.3% of those with PSA > 50 ng/ml, which was statistically significant with the Fischer test.


CONCLUSIONS
Preoperative PSA has a statistically significant correlation with positive nodes, considering 50 ng/ml as the cut-off point. PSA determination in patients that have received no treatment is essential in the diagnosis and evaluation of therapy in prostate cancer.
Scorticati
C
C
Servicio de Urología, Hospital de Clínicas José de San Martín, Buenos Aires, Argentina.
Montes de Oca
L
L
Bencardino
F
F
López
M
M
Suárez
P
P
Bernardo
N
N
Rozanec
J
J
Bellora
O
O
Holst
P
P
Coste Delvecchio
F
F
Scorticati
C
C
D000230:Adenocarcinoma / Q000097:blood* / Q000473:pathology*; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000097:blood* / Q000473:pathology*; D012189:Retrospective Studies
D017430:Prostate-Specific Antigen