title: Multi-purpose mechanical circulatory device.
abstract: A mechanical circulatory assist device for long term use outside the hospital setting has been developed. The device can be used for left, right or bi-ventricular support, and several of the developed technologies are applicable for total artificial hearts and non-pulsatile flow systems. The totally implantable device is principally designed for left ventricular support with implantation in the left hemithorax. The system utilizes transcutaneous energy and information transfer sub-systems, and has no percutaneous connections. In vitro durability testing has been conducted for periods from 1-4 years. Bovine experiments have been conducted with sustained circulation for periods form 1.5 to 96 hours. The in vitro and in vivo evaluation to date has demonstrated that the system can function effectively as a totally implantable ventricular assist device. The transcutaneous energy and information transfer sub-systems provided the ability to power, monitor and control the device, without the need for percutaneous connections. Design optimization and chronic in vivo evaluation is planned.
authors.affiliation: Cardiovascular Devices Division, University of Ottawa Heart Institute, Ontario, Canada.
authors.forename: T V
authors.initials: TV
authors.lastname: Mussivand
authors.forename: P J
authors.initials: PJ
authors.lastname: Hendry
authors.forename: R G
authors.initials: RG
authors.lastname: Masters
authors.forename: W J
authors.initials: WJ
authors.lastname: Keon
mesh_terms: D000818:Animals; D002315:Cardiopulmonary Bypass; D002417:Cattle; D016027:Heart Transplantation / Q000639:trends; D006353:Heart-Assist Devices / Q000592:standards* / Q000639:trends; D066298:In Vitro Techniques; D019736:Prostheses and Implants / Q000592:standards; D011673:Pulsatile Flow; D013997:Time Factors