title: Continuous intraoperative noninvasive cardiac output monitoring using a new thoracic bioimpedance device.
abstract: OBJECTIVE
  To compare a new noninvasive bioimpedance device with the standard thermodilution method during the intraoperative period in high-risk patients undergoing oncological surgery.
  
  
  METHODS
  Prospectively collected data with retrospective analysis.
  
  
  METHODS
  The study was undertaken at a university hospital, single institution.
  
  
  METHODS
  Twenty-three selected adults undergoing extensive, ablative oncological surgery.
  
  
  METHODS
  Simultaneous measurements of cardiac output by a new bioimpedance method and the standard thermodilution method during the intraoperative and immediate postoperative periods.
  
  
  RESULTS
  The correlation coefficient between the two methods was r = 0.89, p < 0.001. Bias and precision analysis between the two techniques showed a mean bias of 0.1 L/min and SD of the bias [precision] of 1.0 L/min [95% level of agreement +2.1 L/min to -1.9 L/min]. After software enhancement, data from the last 11 monitored patients showed improved correlation between the two methods; r = 0.93, mean bias -0.1 L/min, and precision 0.8 L/min. Electrical and motion-induced interference only transiently impaired the performance of the new impedance method.
  
  
  CONCLUSIONS
  This new impedance device is a safe, reliable, clinically acceptable alternative to the invasive thermodilution method in the operating room environment.
authors.affiliation: Department of Anesthesiology, University of Southern California School of Medicine, Los Angeles, USA.
authors.forename: D
authors.initials: D
authors.lastname: Thangathurai
authors.forename: C
authors.initials: C
authors.lastname: Charbonnet
authors.forename: P
authors.initials: P
authors.lastname: Roessler
authors.forename: C C
authors.initials: CC
authors.lastname: Wo
authors.forename: M
authors.initials: M
authors.lastname: Mikhail
authors.forename: R
authors.initials: R
authors.lastname: Yoahida
authors.forename: W C
authors.initials: WC
authors.lastname: Shoemaker
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016477:Artifacts; D015982:Bias; D002277:Carcinoma / Q000601:surgery; D002302:Cardiac Output; D017097:Electric Impedance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D011182:Postoperative Care; D011446:Prospective Studies; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012449:Safety; D012815:Signal Processing, Computer-Assisted; D012984:Software; D013815:Thermodilution