title: Cell size in the lateral geniculate nucleus of cats reared with esotropia and sagittal transection of the optic chiasm.
abstract: We have attempted to investigate the role of extraretinal influences in controlling visual system development by rearing cats with esotropia in combination with sagittal transection of the optic chiasm. This combination leave two intact A1 laminae, one innervated by the deviated eye and one innervated by the unoperated eye and thus minimizes the contributions of retinally mediated influences. Cell size measurements in the dorsal lateral geniculate nucleus revealed that the neurons in the A1 lamina innervated by the deviated eye were, on average, 10-15% smaller than their counterparts in the contralateral A1 lamina.
authors.affiliation: Program in Neural Science, Indiana University, Bloomington, USA. pgarragh@indiana.edu
authors.forename: P E
authors.initials: PE
authors.lastname: Garraghty
authors.forename: J
authors.initials: J
authors.lastname: Besheer
authors.forename: W L
authors.initials: WL
authors.lastname: Salinger
mesh_terms: D000818:Animals; D002415:Cats; D004948:Esotropia / Q000473:pathology*; D007839:Functional Laterality; D005829:Geniculate Bodies / Q000166:cytology / Q000473:pathology*; D009474:Neurons / Q000166:cytology / Q000473:pathology*; D009897:Optic Chiasm / Q000502:physiology*