title: Colonoscopy and biopsy.
abstract: The place of colonoscopy in the management of ulcerative colitis is restricted to clinical situations where the information provided will change clinical management. The information provided will be answers to the questions?inflammatory bowel disease, o r, in the patient with known colitis: inflammatory bowel disease?type?activity extent?dysplasia. Biopsy is pivotal to the diagnosis and provides the certainty of tissue diagnosis, assessment of activity and detection of dysplasia. Sigmoidoscopy is sufficient for providing information for clinical management in most circumstances, but colonoscopy is important where clinical features are disproportionate to sigmoidoscopic findings and systemic parameters of inflammatory activity; to determine type and extent of inflammatory bowel disease and when surveillance needs to start; and for biopsy to detect dysplasia. Ileoscopy is an important aspect of colonoscopy for differential diagnosis, and is the unique definer of total colonoscopy.
authors.affiliation: Department of Gastroenterology, Royal Melbourne Hospital, Victoria, Australia.
authors.forename: F A
authors.initials: FA
authors.lastname: Macrae
authors.forename: P S
authors.initials: PS
authors.lastname: Bhathal
mesh_terms: D001706:Biopsy / Q000009:adverse effects / Q000379:methods; D003093:Colitis, Ulcerative / Q000150:complications / Q000175:diagnosis*; D003110:Colonic Neoplasms / Q000175:diagnosis* / Q000209:etiology; D003113:Colonoscopy / Q000009:adverse effects / Q000379:methods; D003937:Diagnosis, Differential; D006801:Humans; D012307:Risk Factors; D012449:Safety; D012680:Sensitivity and Specificity