Multi-center sestamibi parathyroid imaging study in Hawaii.
Technetium-99m (99mTc) sestamibi (MIBI) was first used as a parathyroid imaging agent in Hawaii in 1991. The purpose of this study was to determine the sensitivity and positive predictive value of the MIBI scan in detecting abnormal parathyroid glands. A retrospective, multi-center study from 1992-1994 involving 33 patients in four hospitals showed the overall sensitivity of the MIBI scan for detecting hyperparathyroid disease was 90%. The positive predictive value was 93%. It was more sensitive in detecting adenomas (95%) than hyperplasia (45%). In conclusion, the MIBI scan can be helpful in detecting abnormal parathyroid glands and may be most useful prior to reoperations for persistent and recurrent hyperparathyroidism.
Cheung
A H
AH
Department of Surgery, John A. Burns School of Medicine, University of Hawaii, Honolulu, USA.
Wheeler
M S
MS
Madanay
L D
LD
Hew
E
E
Coel
M N
MN
Wong
L M
LM
D000236:Adenoma / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D006965:Hyperplasia / Q000000981:diagnostic imaging / Q000473:pathology; D006980:Hyperthyroidism / Q000000981:diagnostic imaging; D010279:Parathyroid Diseases / Q000000981:diagnostic imaging*; D010280:Parathyroid Glands / Q000000981:diagnostic imaging*; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi
D017256:Technetium Tc 99m Sestamibi