title: Central nervous system ischemia after varicella infection and desmopressin therapy for enuresis.
abstract: A 7-year-old boy had a left-sided cerebrovascular accident 48 hours after beginning intranasal desmopressin acetate (DDAVP) therapy for persistent secondary nocturnal enuresis and approximately 2 weeks after varicella infection. A possible connection between desmopressin therapy or varicella infection (or both) and the patients neurologic symptoms is discussed, as is the relationship of desmopressin with hypercoagulability, Suggestions for patient/parent education, medical history taking, and patient surveillance are offered to prescribing physicians.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Michigan State University, College of Osteopathic Medicine, East Lansing 48824, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Wieting
authors.forename: D D
authors.initials: DD
authors.lastname: Dykstra
authors.forename: M P
authors.initials: MP
authors.lastname: Ruggiero
authors.forename: G B
authors.initials: GB
authors.lastname: Robbins
authors.forename: K
authors.initials: K
authors.lastname: Galusha
mesh_terms: D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging / Q000209:etiology*; D002644:Chickenpox / Q000150:complications*; D002648:Child; D003894:Deamino Arginine Vasopressin / Q000009:adverse effects*; D004775:Enuresis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D012076:Renal Agents / Q000009:adverse effects*; D014057:Tomography, X-Ray Computed
chemical_list: D012076:Renal Agents; D003894:Deamino Arginine Vasopressin