title: Chlamydia trachomatis growth stimulates interleukin 8 production by human monocytic U-937 cells.
abstract: Growth of Chlamydia trachomatis serotypes L2 and L3 in a human monocytic cell line, U-937, increased the rate of interleukin 8 (IL-8) release 100-fold. Heat-killed chlamydiae induced a 10-fold-lower level of production of IL-8. IL-8 may play an important role in the inflammatory reaction to chlamydial infection.
authors.affiliation: Laboratoire de Bactériologie-Virologie-Hygiène, Hôpital Saint-Louis,Université Paris VII, France.
authors.forename: A
authors.initials: A
authors.lastname: Bianchi
authors.forename: C
authors.initials: C
authors.lastname: Dosquet
authors.forename: S
authors.initials: S
authors.lastname: Henry
authors.forename: M C
authors.initials: MC
authors.lastname: Couderc
authors.forename: F
authors.initials: F
authors.lastname: Ferchal
authors.forename: C
authors.initials: C
authors.lastname: Scieux
mesh_terms: D002460:Cell Line; D002692:Chlamydia trachomatis / Q000502:physiology*; D006801:Humans; D016209:Interleukin-8 / Q000096:biosynthesis*; D009000:Monocytes / Q000382:microbiology / Q000502:physiology*
chemical_list: D016209:Interleukin-8