title: Immunity status against poliomyelitis in persons 13-14 years old living in Rome.
abstract: The immunity against poliomyelitis in 1000 subjects 13-14 years old was evaluated. Neutralizing antibodies against poliovirus type 1, 2 and 3 were detected in 97.6%, 95.8% and 70% of samples, respectively. 3/1000 (0.3%) subjects were simultaneously seronegative to the three types. WHO does not suggest a protective level of International Units (IU), but our data indicate that such level is 0.45 IU for polio type 1, 0.65 IU for the type 2 and 0.138 for the type 3. A booster dose of vaccine in adolescence to ensure personal and herd immunity is recommended.
authors.affiliation: Department of Experimental Biology, University of Cagliari, Italy.
authors.forename: I
authors.initials: I
authors.lastname: Mastroeni
authors.forename: A M
authors.initials: AM
authors.lastname: Patti
authors.forename: A
authors.initials: A
authors.lastname: Fabrizi
authors.forename: A L
authors.initials: AL
authors.lastname: Santi
authors.forename: A M
authors.initials: AM
authors.lastname: Manduca
authors.forename: N
authors.initials: N
authors.lastname: Vescia
authors.forename: S
authors.initials: S
authors.lastname: Squarcione
authors.forename: G M
authors.initials: GM
authors.lastname: Fara
mesh_terms: D000293:Adolescent; D000914:Antibodies, Viral / Q000097:blood*; D006801:Humans; D007117:Immunization, Secondary; D011051:Poliomyelitis / Q000276:immunology* / Q000517:prevention & control; D017955:Poliovirus / Q000276:immunology*; D012384:Rome
chemical_list: D000914:Antibodies, Viral