The Escherichia coli flagellar transcriptional activator flhD regulates cell division through induction of the acid response gene cadA.
FlhD is a positive regulator of cadA. A mutant with a transposon-mediated lacZ fusion to cadA exhibited a cell division phenotype similar to that of the flhD mutant and had FlhD-dependent beta-galactosidase activity. Under different growth conditions, the cell division rate correlated with the level of expression of cadA.
Prüss
B M
BM
Department of Microbiology and Immunology, University of Illinois at Chicago, 60612-7344, USA. BIRGIT.PRUESS@UIC.EDU
Markovic
D
D
Matsumura
P
P
D002262:Carboxy-Lyases / Q000235:genetics*; D002455:Cell Division / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics*; D004926:Escherichia coli / Q000235:genetics* / Q000254:growth & development; D029968:Escherichia coli Proteins; D005407:Flagella / Q000235:genetics; D015964:Gene Expression Regulation, Bacterial; D005798:Genes, Bacterial; D009154:Mutation; D015534:Trans-Activators / Q000235:genetics*
D004268:DNA-Binding Proteins; D029968:Escherichia coli Proteins; D015534:Trans-Activators; C090553:flhD protein, E coli; D002262:Carboxy-Lyases; C021520:lysine decarboxylase