Hypereosinophilic syndrome or chronic eosinophilic leukemia: report of a case with a lytic bone lesion.
Some cases of hypereosinophilic syndrome and myeloproliferative disorders exhibit common features and thus pose diagnostic and therapeutic problems. We describe a 68-year-old patient who presented with such features and developed lytic lesion in the tibia. Based on our case and a review of literature we suggest that cases like ours should be classified and treated as chronic eosinophilic leukemia (a myeloproliferative disorder) rather than as a hypereosinophilic syndrome or as an atypical chronic myeloid leukemia.
Juneja
S
S
Department of Pathology, Peter MacCallum Cancer Institute, East Melbourne, Victoria, Australia.
Stewart
J
J
McKenzie
A
A
Venter
D
D
Januszewicz
H
H
D000368:Aged; D001847:Bone Diseases / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000145:classification / Q000473:pathology*; D007951:Leukemia, Myeloid / Q000145:classification / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D009196:Myeloproliferative Disorders / Q000145:classification / Q000473:pathology*; D013977:Tibia / Q000473:pathology