[The levels of adenine nucleotides and hypoxanthine in blood of patients on long-term hemodialysis using dialysis fluid containing acetate or bicarbonate].
Intraerythrocyte adenine nucleotides concentration reflects energy balance of red cells and plays pivotal role in their function. In hemodialysed patients both ATP and ADP concentration in red cells was higher than in controls, p < 0.001 and p < 0.005 respectively. But AMP and hypoxanthine did not differ from control. No change of ATP, ADP and AMP was observed after hemodialysis, but hypoxanthine fall significantly, p < 0.001. The pattern of nucleotides concentration and its changes during hemodialysis was the same regardless of the mode of the therapy; e.g. acetate or bicarbonate.
Bułło
B
B
Kliniki Chorób Nerek, Akademii Medycznej w Gdańsku.
Marlewski
M
M
Manitius
J
J
Smoleński
R T
RT
Rutkowski
B
B
D000085:Acetates / Q000494:pharmacology*; D000244:Adenosine Diphosphate / Q000097:blood*; D000255:Adenosine Triphosphate / Q000097:blood*; D000328:Adult; D001639:Bicarbonates / Q000494:pharmacology*; D005260:Female; D015312:Hemodialysis Solutions / Q000494:pharmacology*; D006801:Humans; D019271:Hypoxanthine / Q000097:blood*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis
D000085:Acetates; D001639:Bicarbonates; D015312:Hemodialysis Solutions; D019271:Hypoxanthine; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate