title: Low-sodium diet in pregnancy: effects on blood pressure and maternal nutritional status.
abstract: In ninety-four Dutch nulliparous women the effects of a low-Na diet in pregnancy on blood pressure, energy and nutrient intake, Ca metabolism, Zn and Mg status and body composition were studied longitudinally. The women were randomly divided into an intervention group (n 41), which used a low-Na diet (mean urinary Na excretion 61 mmol/24 h) from week 14 of pregnancy until delivery and a control group (n 53; mean urinary Na excretion 142 mmol/24 h). No effect of the diet on blood pressure was observed. The use of a low-Na diet resulted in significantly reduced intakes of energy, protein, carbohydrates, fat, Ca, Zn, Mg, Fe and cholesterol. However, the women on the low-Na diet appeared to be able to adapt quite well to the reduced intake since Ca, Zn and Mg homeostasis was maintained. In the case of Ca and Mg this was probably due to the observed reduced urinary excretions of these nutrients. Non-significant reductions in weight gain (1.5 kg) and fat-mass gain (0.9 kg) over pregnancy were found in the women on the low-Na diet. No significant effects of the diet on birth weight or placental weight were observed.
authors.affiliation: Department of Obstetrics and Gynaecology, Bosch Medicentrum (Groot Ziekengasthuis), 's-Hertogenbosch, The Netherlands.
authors.forename: G D
authors.initials: GD
authors.lastname: van der Maten
authors.forename: J M
authors.initials: JM
authors.lastname: van Raaij
authors.forename: L
authors.initials: L
authors.lastname: Visman
authors.forename: L J
authors.initials: LJ
authors.lastname: van der Heijden
authors.forename: H P
authors.initials: HP
authors.lastname: Oosterbaan
authors.forename: R
authors.initials: R
authors.lastname: de Boer
authors.forename: T K
authors.initials: TK
authors.lastname: Eskes
authors.forename: J G
authors.initials: JG
authors.lastname: Hautvast
mesh_terms: D000328:Adult; D001794:Blood Pressure / Q000502:physiology*; D001823:Body Composition; D002118:Calcium / Q000378:metabolism; D004039:Diet, Sodium-Restricted; D002149:Energy Intake / Q000502:physiology; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008274:Magnesium / Q000378:metabolism; D009752:Nutritional Status; D011247:Pregnancy / Q000502:physiology*; D011262:Pregnancy Trimester, Second; D011263:Pregnancy Trimester, Third; D012982:Sodium, Dietary / Q000008:administration & dosage*; D015430:Weight Gain; D015032:Zinc / Q000378:metabolism
chemical_list: D012982:Sodium, Dietary; D008274:Magnesium; D015032:Zinc; D002118:Calcium