Changes of glycosaminoglycan composition in aging chicken brain. A preliminary investigation.
The qualitative and quantitative pattern of GAGs was examined by electrophoresis in aging chicken brain in four different stages starting from day 1 to 30 months. GAG content referred to defatted dry tissue exhibits constant decrease. Four main GAGs have been identified with a mobility corresponding to hyaluronate, condroitin sulfate, heparan sulfate and dermatan sulfate controls. Hyaluronate appears the main GAG represented while dermatan sulfate the minor one. Our data show that in chicken brain GAG percentage undergoes age-related changes.
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Institute of Histology and General Embryology, University of Bologna.
Wegelin
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D000375:Aging / Q000378:metabolism*; D000818:Animals; D001923:Brain Chemistry; D002645:Chickens / Q000254:growth & development* / Q000378:metabolism; D002809:Chondroitin Sulfates / Q000032:analysis; D003871:Dermatan Sulfate / Q000032:analysis; D006025:Glycosaminoglycans / Q000032:analysis*; D006497:Heparan Sulfate / Q000032:analysis; D006595:Hexosamines / Q000032:analysis; D006820:Hyaluronic Acid / Q000032:analysis; D014574:Uronic Acids / Q000032:analysis
D002809:Chondroitin Sulfates; D003871:Dermatan Sulfate; D006025:Glycosaminoglycans; D006497:Heparan Sulfate; D006595:Hexosamines; D006820:Hyaluronic Acid; D014574:Uronic Acids