P-SEA: a new efficient assignment of secondary structure from C alpha trace of proteins.
BACKGROUND
The secondary structure is a key element of architectural organization in proteins. Accurate assignment of the secondary structure elements (SSE) (helix, strand, coil) is an essential step for the analysis and modelling of protein structure. Various methods have been proposed to assign secondary structure. Comparative studies of their results have shown some of their drawbacks, pointing out the difficulties in the task of SSE assignment.


RESULTS
We have designed a new automatic method, named P-SEA, to assign efficiently secondary structure from the sole C alpha position. Some advantages of the new algorithm are discussed.


BACKGROUND
The program P-SEA is available by anonymous ftp: ftp.lmcp.jussieu.fr directory: pub/.
Labesse
G
G
Système Moléculaire et Biologie Structurale, Universités Paris 6/Paris 7, CNRS URA 09, France. Labesse@lmcp.jussieu.fr
Colloc'h
N
N
Pothier
J
J
Mornon
J P
JP
D000465:Algorithms; D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics; D002352:Carrier Proteins / Q000737:chemistry / Q000235:genetics; D016208:Databases, Factual; D029968:Escherichia coli Proteins; D008969:Molecular Sequence Data; D017510:Protein Folding; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry* / Q000235:genetics; D012984:Software
C016242:AraF protein, E coli; D001426:Bacterial Proteins; D002352:Carrier Proteins; D029968:Escherichia coli Proteins; D011506:Proteins