Nutritional regulation of insulin-like growth factor-I mRNA expression in barramundi, Lates calcarifer.
The effect of nutritional status on IGF-I mRNA expression in the liver and brain of juvenile barramundi (Lates calcarifer) was investigated. Fish were either fed a satiety ration (SAT) or starved (STV) for 6 weeks. Starved fish demonstrated significantly lower condition factor and hepatic IGF-I mRNA expression at 3 and 6 weeks, when compared with the SAT group. IGF-I mRNA expression in the brain was 10 fold lower than the liver and was not affected by ration size. These results suggest the liver is the major site of IGF-I mRNA synthesis and hepatic but not brain IGF-I mRNA expression is regulated by food availability in juvenile barramundi.
Matthews
S J
SJ
Department of Zoology and Tropical Ecology (Division of Aquaculture), James Cook University of North Queensland, Townsville, Australia.
Kinhult
A K
AK
Hoeben
P
P
Sara
V R
VR
Anderson
T A
TA
D000818:Animals; D001492:Bass / Q000235:genetics* / Q000254:growth & development; D001921:Brain / Q000378:metabolism; D018507:Gene Expression Regulation, Developmental; D007334:Insulin-Like Growth Factor I / Q000235:genetics*; D008099:Liver / Q000378:metabolism; D009752:Nutritional Status; D012333:RNA, Messenger / Q000235:genetics* / Q000378:metabolism*; D013217:Starvation / Q000235:genetics; D014018:Tissue Distribution
D012333:RNA, Messenger; D007334:Insulin-Like Growth Factor I