title: [Acute poisoning by class I anti-arrhythmia agents and by chloroquine].
abstract: Poisonings with class I antiarrhythmic drugs and chloroquine are characterized by their severity, related to their membrane-stabilizing effect. Because of the rapid onset of severe cardiovascular disturbances with circulatory arrest, cardiogenic shock, conduction abnormalities, ventricular dysrhythmia, rapid hospitalisation in an intensive care unit is mandatory with continuous monitoring of electrocardiogram, blood pressure and biological variables. Treatment includes mechanical ventilation, inotropic agents, especially epinephrine, hypertonic sodium salts, and diazepam in case of chloroquine poisoning.
authors.affiliation: Service de réanimation médicale, Hôpitaux universtaires de Strasbourg.
authors.forename: A
authors.initials: A
authors.lastname: Jaeger
authors.forename: O
authors.initials: O
authors.lastname: Raguin
authors.forename: M N
authors.initials: MN
authors.lastname: Liégeon
mesh_terms: D000208:Acute Disease; D000889:Anti-Arrhythmia Agents / Q000506:poisoning*; D018501:Antirheumatic Agents / Q000506:poisoning*; D002738:Chloroquine / Q000506:poisoning*; D006801:Humans; D011041:Poisoning / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy
chemical_list: D000889:Anti-Arrhythmia Agents; D018501:Antirheumatic Agents; D002738:Chloroquine