Albendazole treatment and serological follow-up in hydatid disease of bone.
Case histories of 9 patients with hydatid disease of bone are presented. All except one had undergone previous operations and had received oral albendazole (15 mg/kg/day) in 28 day cycles (6 to 18). The efficacy of chemotherapy was assessed by serological tests for circulating antigen, immunocomplexes and specific antibodies, and by radiography and CT scans. These methods helped to evaluate treatment and showed that the long term administration of albendazole was effective.
Bonifacino
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R
Departamento de Parasitologia, Facultad de Medicina, Montevideo, Uruguay.
Dogliani
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E
Craig
P S
PS
D000284:Administration, Oral; D000328:Adult; D000368:Aged; D015766:Albendazole / Q000627:therapeutic use*; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D000909:Antibodies, Helminth / Q000097:blood; D000936:Antigen-Antibody Complex / Q000097:blood; D000947:Antigens, Helminth / Q000097:blood; D001847:Bone Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000276:immunology; D016903:Drug Monitoring / Q000379:methods*; D004443:Echinococcosis / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000276:immunology; D004446:Echinococcus / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
D000871:Anthelmintics; D000909:Antibodies, Helminth; D000936:Antigen-Antibody Complex; D000947:Antigens, Helminth; D015766:Albendazole