Inositol prevents expression of a genetic model of neural tube defects in mice.
Although up to 70% of neural tube defects (NTDs) can be prevented by adequate folate consumption, some NTDs are unrelated to folate, myo-inositol was found to reduce the incidence of spinal NTDs that are unrelated to folate in curly tail mice.
D000818:Animals; D015870:Gene Expression / Q000187:drug effects; D007294:Inositol / Q000627:therapeutic use*; D051379:Mice; D008818:Mice, Neurologic Mutants; D009436:Neural Tube Defects / Q000235:genetics* / Q000517:prevention & control*
D007294:Inositol