title: Impalpable breast cysts: utility of cytologic examination of fluid obtained with radiologically guided aspiration.
abstract: OBJECTIVE
  To evaluate the utility of cytologic analysis of fluid obtained from impalpable breast cysts by means of radiologically guided aspiration.
  
  
  METHODS
  The authors retrospectively reviewed the reports of cytologic examinations of fluid obtained with sonographically or mammographically guided aspiration of 660 impalpable breast cysts in 583 women during 3 1/2 years.
  
  
  RESULTS
  No malignant cells (541 cysts) or insufficient cellular material (86 cysts) was seen with cytologic examination of 95% of the aspirates. Atypical cells were seen with cytologic examination of fluid from 33 (5%) lesions. None of these 33 lesions were found to represent malignancy at the time of surgical excision (n = 9) or during clinical follow-up (n = 24).
  
  
  CONCLUSIONS
  Routine cytologic examination is unnecessary if the fluid obtained with radiologically guided aspiration from impalpable breast cysts is not bloody.
authors.affiliation: Department of Radiology, Brigham and Women's Hospital, Boston, MA 02115, USA.
authors.forename: D N
authors.initials: DN
authors.lastname: Smith
authors.forename: C M
authors.initials: CM
authors.lastname: Kaelin
authors.forename: C D
authors.initials: CD
authors.lastname: Korbin
authors.forename: W
authors.initials: W
authors.lastname: Ko
authors.forename: J E
authors.initials: JE
authors.lastname: Meyer
authors.forename: G R
authors.initials: GR
authors.lastname: Carter
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle / Q000379:methods*; D005260:Female; D005348:Fibrocystic Breast Disease / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D010173:Palpation; D015641:Radiography, Interventional / Q000379:methods*; D015203:Reproducibility of Results; D012189:Retrospective Studies; D018084:Ultrasonography, Interventional / Q000379:methods*; D016217:Ultrasonography, Mammary