Control of water-borne parasitic diseases with natural products: the potential of Dialium guineense as a molluscicide.
The molluscicidal activity of the fruit and leaves of Dialium guineense was found to be due to glycosides of the triterpenoid oleanolic acid. Three glycosides were isolated from the fruit and a fourth from the leaves and are known compounds. The amount of total saponins present in D. guineense makes it a good candidate for a readily available molluscicide in Nigerian villages.
Houghton
P J
PJ
Department of Pharmacy, King's College London, UK.
Odukoya
O A
OA
Adelusi
A
A
Omogbai
E K
EK
Sanderson
L
L
Whitfield
P J
PJ
D000818:Animals; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D015394:Molecular Structure; D008975:Molluscacides / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D009549:Nigeria; D009828:Oleanolic Acid / Q000031:analogs & derivatives*; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D012552:Schistosomiasis / Q000517:prevention & control; D012908:Snails; D014867:Water
D006027:Glycosides; D008975:Molluscacides; D010936:Plant Extracts; D014867:Water; D009828:Oleanolic Acid