RNA-binding proteins as regulators of gene expression.
A plethora of post-transcriptional mechanisms are involved in essential steps in the pathway of genetic information expression in eukaryotes. These processes are specified by cis-acting signals on RNAs and are mediated by specific trans-acting factors, including RNA-binding proteins and small complementary RNAs. Recent information has begun to define the molecular mechanisms by which RNA-binding proteins recognize specific RNA sequences and influence the processing and function of RNA molecules.
Siomi
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Howard Hughes Medical Institute, University of Pennsylvania School of Medicine Philadelphia 19104-6148, USA. hsiomi@hmivax.humgen.upenn.edu
Dreyfuss
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D000595:Amino Acid Sequence; D000818:Animals; D005786:Gene Expression Regulation / Q000235:genetics*; D006801:Humans; D011487:Protein Conformation; D012313:RNA / Q000502:physiology; D016601:RNA-Binding Proteins / Q000235:genetics*; D015398:Signal Transduction / Q000235:genetics
D016601:RNA-Binding Proteins; D012313:RNA