Avian leukemias and lymphomas: interplay between retroviruses and herpesviruses.
Avian leukemias and lymphomas are caused primarily by retroviruses and herpesviruses. The protooncogenes activated by avian retroviral insertions in B & T-cell lymphomas will be summarized, with discussion on a new common insertion site, bravo, associated with RAV-O LTR insertion. Two novel interactions between avian retroviruses and Marek's disease herpesvirus (MDV) will be described: one involves direct interactions between putative viral oncoproteins and the other integrative recombination between these two viruses.
Robinson
D
D
Department of Molecular Biology & Microbiology, Case Western Reserve University, School of Medicine, Cleveland, OH 44106, USA.
Liu
J L
JL
Jones
D
D
Brunovskis
P
P
Qian
Z
Z
Isfort
R
R
Tillotson
J K
JK
Lee
L
L
Witter
R
R
Salter
D
D
Crittenden
L
L
Hughes
S
S
Kung
H J
HJ
D001355:Alpharetrovirus / Q000235:genetics; D000818:Animals; D001353:Avian Leukosis / Q000821:virology*; D002645:Chickens; D004251:DNA Transposable Elements; D006564:Herpesviridae / Q000235:genetics* / Q000472:pathogenicity; D007680:Kidney Neoplasms / Q000662:veterinary / Q000821:virology; D016393:Lymphoma, B-Cell / Q000662:veterinary* / Q000821:virology; D016399:Lymphoma, T-Cell / Q000662:veterinary* / Q000821:virology; D011201:Poultry Diseases; D011519:Proto-Oncogenes; D011995:Recombination, Genetic; D012190:Retroviridae / Q000235:genetics* / Q000472:pathogenicity; D014412:Tumor Virus Infections / Q000821:virology; D016662:Virus Integration; D009396:Wilms Tumor / Q000662:veterinary / Q000821:virology
D004251:DNA Transposable Elements