title: [A three-year follow-up study of hepatitis C virus infected individuals from Beixie village, Gu-an county, Hebel province, China].
abstract: A total number of 42 anti-HCV positive individuals from Beixie village, Gu-an county, was followed for three years to study the dynamic change of alanine aminotransminase (ALT), anti-HCV titers as well as HCV RNA in serum. Research results showed that 18.1% to 26.2% of the individuals exhibited a rise in ALT values while the positive rate of HCV RNA was 80%. The yearly negative seroconversion rate of anti-HCV was only 0.95%. The geometric mean titer (GMT) of anti-HCV was around 160 and showed no significant difference between the paired serum samples collected in 1991 and in 1994. There were no statistical associations between the GMT value of anti-HCV and ALT level as well as HCV RNA in serum.
authors.affiliation: Department of Epidemiology, Academy of Military Medical Sciences, Beijing.
authors.forename: S X
authors.initials: SX
authors.lastname: Tang
authors.forename: D Q
authors.initials: DQ
authors.lastname: Sun
authors.forename: W R
authors.initials: WR
authors.lastname: Chen
mesh_terms: D000328:Adult; D000595:Amino Acid Sequence; D002681:China; D005260:Female; D005500:Follow-Up Studies; D016174:Hepacivirus / Q000235:genetics*; D006526:Hepatitis C / Q000097:blood*; D018937:Hepatitis C Antibodies / Q000097:blood*; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D012367:RNA, Viral / Q000097:blood*
chemical_list: D018937:Hepatitis C Antibodies; D012367:RNA, Viral