Failure to induce formation of proteinase K resistant fibrils in pigeons through experimental infection with paramyxovirus type 1.
Ten racing pigeons were infected experimentally with the paramyxovirus (PMV) type 1 of the pigeon. Within twelve weeks of observation, they were euthanized at different times. Their brains were examined for proteinase K resistant fibrils and histopathologically for spongiform lesions. No proteinase K resistant fibrils and no spongiform lesions could be detected in any case. Therefore, it is estimated that PMV type 1 of the pigeon is not likely to induce pathogenic mechanisms assumed for transmissible spongiform encephalopathies.
Kostka
V M
VM
Institute for Avian Diseases, Justus-Liebig-Universität Giessen, Germany.
Groschup
M H
MH
Kaleta
E F
EF
Schröder
J
J
D000818:Animals; D018109:Avulavirus; D001921:Brain / Q000473:pathology* / Q000821:virology; D002645:Chickens; D010856:Columbidae; D019286:Endopeptidase K; D011328:Prions / Q000302:isolation & purification; D019351:Rubulavirus Infections / Q000473:pathology*
D011328:Prions; D019286:Endopeptidase K