Antinociceptive components of Ganoderma lucidum.
The antinociceptive effects 134 extracts prepared from 45 species of mushrooms were examined by the acetic acid-induced writhing method. From the CH2Cl2 extract of Ganoderma lucidum among the active extracts, ganoderic acids A, B, G and H and compound C6 were isolated as the antinociceptive components.
Koyama
K
K
Department of Pharmacognosy and Phytochemistry, Meiji College of Pharmacy, Tokyo, Japan.
Imaizumi
T
T
Akiba
M
M
Kinoshita
K
K
Takahashi
K
K
Suzuki
A
A
Yano
S
S
Horie
S
S
Watanabe
K
K
Naoi
Y
Y
D019342:Acetic Acid; D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D001241:Aspirin / Q000494:pharmacology; D001487:Basidiomycota; D006538:Heptanoic Acids / Q000494:pharmacology*; D007564:Japan; D007810:Lanosterol / Q000031:analogs & derivatives* / Q000494:pharmacology; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D010146:Pain / Q000139:chemically induced / Q000188:drug therapy; D010936:Plant Extracts / Q000494:pharmacology*; D013045:Species Specificity
D000700:Analgesics; D006538:Heptanoic Acids; D010936:Plant Extracts; C515007:ganoderic acid H; D007810:Lanosterol; C515005:ganoderic acid A; C515006:ganoderic acid F; D019342:Acetic Acid; D001241:Aspirin