title: Antibacterial activity of dentin bonding systems, resin-modified glass ionomers, and polyacid-modified composite resins.
abstract: The antibacterial effects of the dentin bonding systems Syntac, ProBOND, Gluma 3-Step, the resin-modified glass ionomers Photac-Fil, Fuji Lining LC, Fuji II LC, and the polyacid-modified composite resins VariGlass, Geristore, and Infinity were evaluated using the cariogenic bacteria S mutans, L salivarius, S sobrinus, and A viscosus in vitro with a modified cylinder drop plate agar diffusion assay. All glass ionomers, the polyacid-modified composites, and the primers and adhesives of the dentin bonding systems exhibited various degrees of antibacterial activity against most of the test bacteria. The antibacterial activity of the adhesives of dentin bonding systems was anticipated because of the glutaraldehyde used in their formulations. However, the antibacterial activity of the various primers was unexpected and indicates a dual antibacterial action of these systems.
authors.affiliation: University of Connecticut Health Center, School of Dental Medicine, Department of Restorative Dentistry and Endodontology, Farmington 06032, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Meiers
authors.forename: G A
authors.initials: GA
authors.lastname: Miller
mesh_terms: D000180:Acrylic Resins / Q000494:pharmacology; D016924:Actinomyces viscosus / Q000187:drug effects; D000891:Anti-Infective Agents, Local / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D003188:Composite Resins / Q000737:chemistry / Q000494:pharmacology*; D017220:Dentin-Bonding Agents / Q000737:chemistry / Q000494:pharmacology*; D005899:Glass Ionomer Cements / Q000737:chemistry / Q000494:pharmacology*; D005976:Glutaral / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D007778:Lactobacillus / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011109:Polymethacrylic Acids / Q000494:pharmacology; D019279:Resin Cements / Q000737:chemistry / Q000494:pharmacology*; D012117:Resins, Synthetic / Q000494:pharmacology; D013291:Streptococcus / Q000187:drug effects
chemical_list: D000180:Acrylic Resins; D000891:Anti-Infective Agents, Local; D003188:Composite Resins; D017220:Dentin-Bonding Agents; C079765:Fuji II LC cement; C074933:Geristore; D005899:Glass Ionomer Cements; C084549:Infinity resin; C088835:Photac-Bond; D011109:Polymethacrylic Acids; D019279:Resin Cements; D012117:Resins, Synthetic; C078484:Syntac dentine adhesive; C081982:VariGlass VLC; C061499:Ketac-Bond; C062652:Prisma Universal Bond; C084541:Fuji glass-ionomer lining cement; C044372:Gluma; D005976:Glutaral