title: Autonomic dysfunction associated with locked-in syndrome in a child.
abstract: This is a report of a young boy with the unusual combination of autonomic dysfunction with locked-in syndrome following multiple shunt revisions for hydrocephalus. A review of the literature on autonomic dysfunction syndrome and the complex clinical picture of the combined syndromes in a pediatric patient are discussed. The marked effectiveness of treatment with carbidopa/levodopa over bromocriptine for both syndromes is noted.
authors.affiliation: Tulsa Developmental Pediatrics and Center of Family Psychology, Oklahoma, USA.
authors.forename: J S
authors.initials: JS
authors.lastname: Scott
authors.forename: R R
authors.initials: RR
authors.lastname: Ockey
authors.forename: G E
authors.initials: GE
authors.lastname: Holmes
authors.forename: G
authors.initials: G
authors.lastname: Varghese
mesh_terms: D001342:Autonomic Nervous System Diseases / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D001971:Bromocriptine / Q000627:therapeutic use; D002230:Carbidopa / Q000627:therapeutic use; D002648:Child; D015259:Dopamine Agents / Q000627:therapeutic use; D018491:Dopamine Agonists / Q000627:therapeutic use; D005334:Fever / Q000209:etiology; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000601:surgery; D006973:Hypertension / Q000209:etiology; D006985:Hyperventilation / Q000209:etiology; D007031:Hypothalamus / Q000503:physiopathology; D008297:Male; D008636:Mesencephalon / Q000503:physiopathology; D011782:Quadriplegia / Q000150:complications*; D013577:Syndrome; D017287:Ventriculoperitoneal Shunt
chemical_list: D015259:Dopamine Agents; D018491:Dopamine Agonists; D001971:Bromocriptine; D002230:Carbidopa