Proptosis as the manifesting sign of Weber-Christian disease.
OBJECTIVE
To identify proptosis as a manifesting sign of Weber-Christian disease (recurrent febrile nodular panniculitis).


METHODS
Case report. A 61-year-old man had signs of right proptosis and orbital inflammation that resolved with oral corticosteroid therapy. Orbital inflammation later recurred with associated cutaneous nodules, myalgia, nausea, and malaise.


RESULTS
Rheumatologic evaluation and subcutaneous nodule biopsy led to the diagnosis of Weber-Christian disease. The patient required systemic immunosuppressive agents to control the disease.


CONCLUSIONS
This case shows the rare finding of proptosis as the manifesting sign of Weber-Christian disease.
Cook
J N
JN
University of California, Davis, School of Medicine, USA.
Kikkawa
D O
DO
D001706:Biopsy; D005094:Exophthalmos / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009915:Orbit / Q000000981:diagnostic imaging; D010201:Panniculitis, Nodular Nonsuppurative / Q000175:diagnosis* / Q000188:drug therapy; D014057:Tomography, X-Ray Computed
D005938:Glucocorticoids; D007166:Immunosuppressive Agents