Acute onset of dermatitis, hepatitis, and eosinophilia.
A 48-year-old man presented to the emergency department complaining of fever, chills, myalgias, and diffuse abdominal discomfort of four days' duration. A nonpruritic rash had developed on his left palm, arms, legs, and buttocks on the fourth day. He had not had respiratory symptoms, nausea, vomiting, or diarrhea.
Reichmuth
D A
DA
Department of Internal Medicine, University of South Florida College of Medicine, Tampa, USA.
Matfin
G
G
Adelman
H M
HM
D000208:Acute Disease; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000209:etiology*; D004802:Eosinophilia / Q000139:chemically induced*; D004892:Erythema Multiforme / Q000139:chemically induced*; D006801:Humans; D007660:Ketoprofen / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007660:Ketoprofen