Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1 beta-converting enzyme inhibitor.
Dolle
R E
RE
Sanofi Winthrop Inc., Collegeville, Pennsylvania 19426, USA.
Prasad
C V
CV
Prouty
C P
CP
Salvino
J M
JM
Awad
M M
MM
Schmidt
S J
SJ
Hoyer
D
D
Ross
T M
TM
Graybill
T L
TL
Speier
G J
GJ
Uhl
J
J
Miller
B E
BE
Helaszek
C T
CT
Ator
M A
MA
D000818:Animals; D001381:Azepines / Q000737:chemistry* / Q000493:pharmacokinetics; D004285:Dogs; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000493:pharmacokinetics; D008657:Metabolic Clearance Rate; D011724:Pyridazines / Q000737:chemistry* / Q000493:pharmacokinetics; D015843:Serpins / Q000138:chemical synthesis* / Q000493:pharmacokinetics; D014764:Viral Proteins
D001381:Azepines; D004791:Enzyme Inhibitors; D011724:Pyridazines; D015843:Serpins; D014764:Viral Proteins; C074641:interleukin-1beta-converting enzyme inhibitor