title: [Changes in central hemodynamics and their correction during reconstructive surgery in Leriche's syndrome].
abstract: Study of the parameters of central hemodynamics in the course of aortofemoral shunting for Leriche's syndrome revealed the role of lipid peroxidation dysfunction in the genesis of cardiovascular disorders developing in the immediate postoperative period. The postoperative period is characterized by expressed hypotension developing in the presence of activation of lipid peroxidation and suppression of plasma antioxidative activity. The authors recommend alpha-tocopherol, cytochrome C, and dalargin to prevent these hemodynamic disorders.
authors.forename: M I
authors.initials: MI
authors.lastname: Neĭmark
authors.forename: V V
authors.initials: VV
authors.lastname: Shmelev
mesh_terms: D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000975:Antioxidants / Q000378:metabolism; D001012:Aorta, Abdominal / Q000601:surgery; D001807:Blood Vessel Prosthesis; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control; D016308:Enkephalin, Leucine-2-Alanine / Q000031:analogs & derivatives / Q000627:therapeutic use; D005263:Femoral Artery / Q000601:surgery; D006439:Hemodynamics; D006801:Humans; D007022:Hypotension / Q000209:etiology / Q000503:physiopathology / Q000517:prevention & control; D007925:Leriche Syndrome / Q000601:surgery*; D015227:Lipid Peroxidation; D011183:Postoperative Complications / Q000209:etiology* / Q000503:physiopathology / Q000517:prevention & control; D014810:Vitamin E / Q000627:therapeutic use
chemical_list: D000276:Adjuvants, Immunologic; D000975:Antioxidants; D014810:Vitamin E; D016308:Enkephalin, Leucine-2-Alanine; C040996:enkephalin-Leu, Ala(2)-Arg(6)-