title: APO E polymorphism in Spanish and Moroccan populations.
abstract: Apolipoprotein E (apoE) gene polymorphism was analyzed by polymerase chain reaction in one Moroccan and six Spanish populations, a total of 660 individuals. No significant differences were observed between samples, and the mean relative frequencies (with 95% confidence intervals) found were 0.104 (0.069-0.139) for the epsilon4 allele, 0.855 (0.813-0.897) for epsilon3 and 0.041 (0.015-0.067) for epsilon2. Frequencies of the epsilon4 allele were low in comparison to Northern European populations, but similar to those reported for other South-European populations. The presence of a rare mutation, E2 Christchurch, in one Basque individual was confirmed by sequence analysis.
authors.affiliation: Laboratori d'Antropologia, Facultat de Biologia, Universitat de Barcelona, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Valveny
authors.forename: E
authors.initials: E
authors.lastname: Esteban
authors.forename: M
authors.initials: M
authors.lastname: Kandil
authors.forename: P
authors.initials: P
authors.lastname: Moral
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000483:Alleles; D001057:Apolipoproteins E / Q000235:genetics*; D005260:Female; D005820:Genetic Testing; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D009018:Morocco; D011110:Polymorphism, Genetic; D013030:Spain
chemical_list: D001057:Apolipoproteins E