title: Benign and malignant cartilage tumors of bone and joint: their anatomic and theoretical basis with an emphasis on radiology, pathology and clinical biology. I. The intramedullary cartilage tumors.
abstract: We reviewed 845 cases of benign and 356 cases of malignant cartilaginous tumors from a total of 3067 primary bone tumors in our database. Benign cartilaginous lesions are unique because the epiphyseal plate has been implicated in the etiology of osteochondroma, enchondroma (single or multiple), periosteal chondromas and chondroblastoma. In the first part of this paper, we will review important clinical, radiologic and histologic features of intramedullary cartilaginous lesions in an attempt to support theories related to anatomic considerations and pathogenesis.
authors.affiliation: Orthopaedic Oncology Service, Orthopaedic Hospital, Los Angeles, CA 90007, USA.
authors.forename: E W
authors.initials: EW
authors.lastname: Brien
authors.forename: J M
authors.initials: JM
authors.lastname: Mirra
authors.forename: R
authors.initials: R
authors.lastname: Kerr
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology; D002356:Cartilage; D002648:Child; D002804:Chondroblastoma / Q000473:pathology; D002812:Chondroma / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000628:therapy; D002813:Chondrosarcoma / Q000209:etiology / Q000473:pathology; D004687:Enchondromatosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology / Q000628:therapy; D005260:Female; D006801:Humans; D007223:Infant; D007592:Joint Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009372:Neoplasms, Connective Tissue / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D010009:Osteochondrodysplasias / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D014057:Tomography, X-Ray Computed