Effects of nicorandil, an antianginal potassium channel opener, on left ventricular systolic and diastolic function in patients with chronic coronary artery disease.
We compared the effects of nicorandil with nitroglycerin and nifedipine on left ventricular function. Intravenous nicorandil may be a balanced-typed vasodilator and useful in patients with left ventricular systolic and diastolic dysfunction.
Murayama
S
S
First Department of Internal Medicine, Mie University, Edobashi, Tsu, Japan.
Yamakado
T
T
Nakano
T
T
D000328:Adult; D000368:Aged; D002908:Chronic Disease; D003327:Coronary Disease / Q000503:physiopathology*; D003971:Diastole; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009536:Niacinamide / Q000031:analogs & derivatives* / Q000494:pharmacology; D020108:Nicorandil; D009543:Nifedipine / Q000494:pharmacology; D005996:Nitroglycerin / Q000494:pharmacology; D015221:Potassium Channels / Q000187:drug effects; D013599:Systole; D014665:Vasodilator Agents / Q000494:pharmacology*; D016277:Ventricular Function, Left / Q000187:drug effects*; D017725:Ventricular Pressure
D015221:Potassium Channels; D014665:Vasodilator Agents; D009536:Niacinamide; D020108:Nicorandil; D005996:Nitroglycerin; D009543:Nifedipine