[Pulmonary epithelioid hemangioendothelioma (or IVBAT). Report of a case of exclusively myxoid form].
Epithelioid hemangioendothelioma of the lung, therefore labeled as IntraVascular BronchioAlveolar Tumor (IVBAT), is a tumor of endothelial origin; its presentation with multiple pulmonary nodules radiographically suggests metastatic disease. We describe here an epithelioid hemangioendothelioma with an exclusively myxoid pattern. The tumor was composed of nodules extending in a polypoid fashion from the alveolar septa. The cells within the tumor were epithelial-like and contained cytoplasmic lacunae positive for anti-FVIII, CD31 and CD34 antibodies. According to usual criteria, it was considered as a tumor of low grade malignancy, without vascular or bronchiolar extension or cytonuclear atypia and mitosis; the prognosis, difficult to determine, depends on locoregional tumor progression.
Lantuéjoul
S
S
Service de Pathologie Cellulaire, CHU A. Michallon, La Tronche.
Esvant
H
H
Brambilla
C
C
Brambilla
E
E
D018323:Hemangioendothelioma, Epithelioid / Q000473:pathology*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009383:Neoplasms, Vascular Tissue / Q000473:pathology*