Amine neurotransmitter levels in male and female rats through developmental periods.
Monoamines (MA) such as dopamine (DA), norepinephrine (NE), and 5-hydroxytryptamine (5-HT) are now generally regarded as widely distributed and essential endogenous mediators contributing to the integration of reproductive physiology. MA measured in the hypothalamus tissue of male and female rats aged 1 to 90 days showed its own characteristic development pattern. Significant differences were observed at 5, 15, and 90 days of age in NE mean levels and at all ages except for 3 days of age in 5-HT mean levels. In contrast, no sex differences were seen in DA mean levels.
Valencia-Sánchez
A
A
UIM en Farmacología, Coordinación Investigación Biomédica, México, DF, México.
Esparza-Avalos
N S
NS
Cruz
M L
ML
Ortega-Corona
B G
BG
D000375:Aging / Q000378:metabolism; D000818:Animals; D015306:Biogenic Monoamines / Q000378:metabolism*; D004298:Dopamine / Q000378:metabolism; D005260:Female; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism; D007031:Hypothalamus / Q000254:growth & development / Q000378:metabolism*; D008297:Male; D009638:Norepinephrine / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D012701:Serotonin / Q000378:metabolism
D015306:Biogenic Monoamines; D012701:Serotonin; D006897:Hydroxyindoleacetic Acid; D004298:Dopamine; D009638:Norepinephrine