title: Management of laryngotracheobronchial sequelae and complications of relapsing polychondritis.
abstract: Relapsing polychondritis is a rare multisystem disorder of unknown etiology characterized by recurrent inflammation and degeneration of cartilage and connective tissue. Laryngotracheobronchial complications are the most severe manifestations of the disease and present the most challenging management decisions. We present four cases of relapsing polychondritis with laryngotracheobronchial manifestations that illustrate the clinical features and review the treatment options.
authors.affiliation: The Royal National Throat, Nose and Ear Hospital, London, United Kingdom.
authors.forename: P D
authors.initials: PD
authors.lastname: Spraggs
authors.forename: P M
authors.initials: PM
authors.lastname: Tostevin
authors.forename: D J
authors.initials: DJ
authors.lastname: Howard
mesh_terms: D000328:Adult; D000402:Airway Obstruction / Q000209:etiology; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001982:Bronchial Diseases / Q000209:etiology*; D002245:Carbon Dioxide; D004487:Edema / Q000209:etiology; D004890:Erythema / Q000209:etiology; D005260:Female; D006801:Humans; D007818:Laryngeal Diseases / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D007820:Laryngeal Mucosa / Q000473:pathology; D053685:Laser Therapy; D008875:Middle Aged; D010347:Patient Care Planning; D011081:Polychondritis, Relapsing / Q000150:complications* / Q000503:physiopathology; D011239:Prednisolone / Q000627:therapeutic use; D014133:Tracheal Diseases / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D014135:Tracheal Stenosis / Q000209:etiology
chemical_list: D000893:Anti-Inflammatory Agents; D002245:Carbon Dioxide; D011239:Prednisolone