title: Cigarette smoking, serum lipids, folate, and vitamin B12 in lung cancer.
abstract: The purpose of our study was to evaluate the effects of cigarette smoking and serum lipids, folate, and vitamin B12 on the development of lung cancer in the Turkish population. The study group consisted of patients with histologically proven lung cancer and the control group comprised healthy smokers being followed in our smoking cessation outpatient department. Smoking history was obtained from all subjects and serum total cholesterol, HDL cholesterol, triglycerides, vitamin B12, and folate levels were measured. Pack/years of cigarettes smoked were significantly higher in the subjects with lung cancer than in the control group (p < 0.01). Serum total cholesterol, HDL cholesterol, triglyceride, serum folate, and vitamin B12 levels were within normal limits in both groups (p < 0.05), but serum vitamin B12 levels were statistically significantly higher (p < 0.01) in the cancer group than in the controls. In our study, we did not observe low levels of serum cholesterol, vitamin B12, or folate in the lung cancer patients.
authors.affiliation: Department of Chest Diseases, Uludağ University School of Medicine, Bursa, Turkey.
authors.forename: E
authors.initials: E
authors.lastname: Gürdal-Yüksel
authors.forename: M
authors.initials: M
authors.lastname: Karadağ
authors.forename: N
authors.initials: N
authors.lastname: Ozyardimci
authors.forename: A E
authors.initials: AE
authors.lastname: Kunt-Uzaslan
authors.forename: T
authors.initials: T
authors.lastname: Yarkin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002784:Cholesterol / Q000097:blood; D005260:Female; D005492:Folic Acid / Q000097:blood*; D006801:Humans; D008055:Lipids / Q000097:blood*; D008075:Lipoproteins, HDL / Q000097:blood; D008175:Lung Neoplasms / Q000097:blood* / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D010947:Plants, Toxic; D012907:Smoking / Q000009:adverse effects; D013997:Time Factors; D014026:Nicotiana; D014280:Triglycerides / Q000097:blood; D014421:Turkey / Q000453:epidemiology; D014805:Vitamin B 12 / Q000097:blood*
chemical_list: D008055:Lipids; D008075:Lipoproteins, HDL; D014280:Triglycerides; D005492:Folic Acid; D002784:Cholesterol; D014805:Vitamin B 12