[Patterns in the change of the evoked skin autonomic potential in nervous system diseases].
The study of sympathetic skin response (SSR) was performed both in 30 healthy volunteers either in rest or after pharmacological preparations administration (reserpine, sydnocarb, gammalone) and in 48 patients with autonomic disfunction, syringomyelia, polyneuropathy. It was determined that two processes were presented in SSR structure, exactly: the first one which included I and III phases and was bound with trophotropic functions and the second process which was presented by II phase only and reflected the activity of ergotropic functions. The latent period of SSR reflected the tonus of the sympathetic nervous system. It was established that SSR changed regularly in the nervous systems diseases studied: thus, increase or decrease of the latent period as well as of the amplitudes of SSR phases were observed in autonomic disfunction while depression or absence of SSR took place in syringomyelia or polyneuropathies. The data obtained testified the results of the other authors about possibility of SSR usage for diagnosis of both central and peripheric autonomic disturbances.
Mikhaĭlenko
A A
AA
Odinak
M M
MM
Ivanov
Iu S
IuS
Kotel'nikov
S A
SA
Semin
G F
GF
Shustov
E B
EB
D000293:Adolescent; D018663:Adrenergic Agents / Q000494:pharmacology; D000328:Adult; D001341:Autonomic Nervous System / Q000187:drug effects / Q000503:physiopathology*; D005071:Evoked Potentials / Q000187:drug effects / Q000502:physiology; D018682:GABA Agents / Q000494:pharmacology; D006801:Humans; D009422:Nervous System Diseases / Q000503:physiopathology*; D011115:Polyneuropathies / Q000503:physiopathology; D011930:Reaction Time / Q000187:drug effects / Q000502:physiology; D012016:Reference Values; D012110:Reserpine / Q000494:pharmacology; D012867:Skin / Q000187:drug effects / Q000294:innervation / Q000503:physiopathology*; D013558:Sydnones / Q000494:pharmacology; D013595:Syringomyelia / Q000503:physiopathology; D005680:gamma-Aminobutyric Acid / Q000494:pharmacology
D018663:Adrenergic Agents; D018682:GABA Agents; D013558:Sydnones; D005680:gamma-Aminobutyric Acid; D012110:Reserpine; C009257:sidnocarb