title: Idiopathic CD4+ T-lymphocytopenia and recurrent vulvar intraepithelial neoplasia.
abstract: BACKGROUND
  CD4+ T-lymphocytopenia immunodeficiency without human immunodeficiency virus (HIV) infection has been reported recently. The association between immunodeficiency and anogenital neoplasia secondary to human papillomavirus infections is well documented.
  
  
  METHODS
  A woman with recurrent vulvar intraepithelial neoplasia (VIN) had idiopathic CD4+ T-lymphocytopenia without HIV infection.
  
  
  CONCLUSIONS
  Human papillomavirus-related VIN may be associated with idiopathic CD4+ T-lymphocytopenia.
authors.affiliation: Department of Gynecologic Oncology, City of Hope National Medical Center, Durate, California, USA.
authors.forename: K
authors.initials: K
authors.lastname: Park
authors.forename: B J
authors.initials: BJ
authors.lastname: Monk
authors.forename: S
authors.initials: S
authors.lastname: Wilczynski
authors.forename: J I
authors.initials: JI
authors.lastname: Ito
authors.forename: S A
authors.initials: SA
authors.lastname: Vasilev
mesh_terms: D002278:Carcinoma in Situ / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000150:complications*; D018344:T-Lymphocytopenia, Idiopathic CD4-Positive / Q000209:etiology*; D014846:Vulvar Neoplasms / Q000150:complications*