Idiopathic CD4+ T-lymphocytopenia and recurrent vulvar intraepithelial neoplasia.
BACKGROUND
CD4+ T-lymphocytopenia immunodeficiency without human immunodeficiency virus (HIV) infection has been reported recently. The association between immunodeficiency and anogenital neoplasia secondary to human papillomavirus infections is well documented.


METHODS
A woman with recurrent vulvar intraepithelial neoplasia (VIN) had idiopathic CD4+ T-lymphocytopenia without HIV infection.


CONCLUSIONS
Human papillomavirus-related VIN may be associated with idiopathic CD4+ T-lymphocytopenia.
Park
K
K
Department of Gynecologic Oncology, City of Hope National Medical Center, Durate, California, USA.
Monk
B J
BJ
Wilczynski
S
S
Ito
J I
JI
Vasilev
S A
SA
D002278:Carcinoma in Situ / Q000150:complications*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000150:complications*; D018344:T-Lymphocytopenia, Idiopathic CD4-Positive / Q000209:etiology*; D014846:Vulvar Neoplasms / Q000150:complications*