Polycystic ovary syndrome. An autoimmune disease?
OBJECTIVE
To determine whether there is an autoimmune cause of polycystic ovary disease (PCOD) implicating antiovarian antibodies in the pathophysiology of the syndrome.


METHODS
This study examined 31 women diagnosed as having PCOD according to internationally recognized criteria and who attended our infertility clinic during 1994-1995.


RESULTS
We could not confirm the findings of previous studies. Only one patient in our group with type II diabetes mellitus had antiovarian antibodies present in her serum.


CONCLUSIONS
It seems that an autoimmune mechanism probably is not of prime importance in this multifaceted syndrome.
Rojansky
N
N
Department of Obstetrics and Gynecology, Hadassah Hebrew University Medical Center Ein-Kerein, Jerusalem, Israel.
Roll
D
D
Meirow
D
D
D000328:Adult; D001323:Autoantibodies / Q000032:analysis* / Q000276:immunology; D001327:Autoimmune Diseases / Q000097:blood / Q000276:immunology*; D005215:Fasting; D005260:Female; D006801:Humans; D007328:Insulin / Q000097:blood; D010053:Ovary / Q000276:immunology*; D011085:Polycystic Ovary Syndrome / Q000097:blood / Q000276:immunology*; D011446:Prospective Studies; D013739:Testosterone / Q000097:blood
D001323:Autoantibodies; D007328:Insulin; D013739:Testosterone