Inhibition of ICE slows ALS in mice.
Friedlander
R M
RM
Brown
R H
RH
Gagliardini
V
V
Wang
J
J
Yuan
J
J
D000690:Amyotrophic Lateral Sclerosis / Q000235:genetics / Q000628:therapy*; D000818:Animals; D020170:Caspase 1; D003546:Cysteine Endopeptidases / Q000235:genetics*; D015853:Cysteine Proteinase Inhibitors / Q000627:therapeutic use; D004195:Disease Models, Animal; D005260:Female; D006801:Humans; D007375:Interleukin-1; D008297:Male; D051379:Mice; D008822:Mice, Transgenic; D009154:Mutation
D015853:Cysteine Proteinase Inhibitors; D007375:Interleukin-1; D003546:Cysteine Endopeptidases; D020170:Caspase 1