Baseline electroencephalographic tracings in rabbits differ significantly according to 'acute' or 'chronic' preparation. A computerized study.
Baseline electroencephalographic (EEG) tracings recorded from 'acute' and 'chronic' rabbits were compared by computerized spectral analysis. The results showed that baseline EEG activity of rabbits differ significantly and markedly according to acute or chronic preparation. It is suggested that this finding should be taken into account when studying the EEG effects of centrally acting drugs.
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Pharmacology Department, Istituto Superiore di Sanità, Roma, Italy.
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D000818:Animals; D002540:Cerebral Cortex / Q000187:drug effects / Q000502:physiology*; D004567:Electrodes, Implanted; D004569:Electroencephalography / Q000187:drug effects / Q000295:instrumentation*; D005071:Evoked Potentials / Q000187:drug effects / Q000502:physiology; D008297:Male; D008959:Models, Neurological; D011619:Psychotropic Drugs / Q000494:pharmacology; D011817:Rabbits; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*
D011619:Psychotropic Drugs