title: The role of Actinobacillus actinomycetemcomitans in the pathogenesis of periodontal disease.
abstract: Periodontal disease consists of a constellation of complex bacterium-host cell interactions. One example of these oral pathogens, Actinobacillus actinomycetemcomitans, has an arsenal of putative virulence determinants that account for its potent periodontopathogenicity. Of these determinants, invasion of host cells and leukocytotoxicity have been studied extensively.
authors.affiliation: Dept of Microbiology and Molecular Genetics, College of Medicine and College of Agricultural and Life Sciences, University of Vermont, Burlington 05405, USA.
authors.forename: D H
authors.initials: DH
authors.lastname: Meyer
authors.forename: P M
authors.initials: PM
authors.lastname: Fives-Taylor
mesh_terms: D000189:Actinobacillus Infections / Q000276:immunology / Q000382:microbiology*; D016976:Aggregatibacter actinomycetemcomitans / Q000472:pathogenicity*; D001427:Bacterial Toxins / Q000633:toxicity; D006790:Host-Parasite Interactions; D006801:Humans; D007962:Leukocytes / Q000382:microbiology; D010510:Periodontal Diseases / Q000382:microbiology*; D014774:Virulence
chemical_list: D001427:Bacterial Toxins