[The clinico-immunological effects of leukinferon in the treatment of patients with acute suppurative pyelonephritis].
A many as 20 patients with acute purulent pyelonephritis were studied for clinical and immunological effects of leukinferone. The above patients were convalescent earlier than control subjects. There were instances where clinical status was not accompanied by shifts in immunity. However, on an average in the group, such parameters as level of lymphocytes, amounts of B-cells, Igs G, A, T-helpers, and Tx/Tc ratio were found to be increased as was activity of EK-cells. Stimulating effects of leukinferone were particularly pronounced in those patients with decreased values for immunological status. A conclusion is reached to the effect that patients with acute pyelonephritis may benefit from those treatments involving the use of the above drug preparation.
Vozianov
A F
AF
Kuznetsov
V P
VP
Driianskaia
V E
VE
Pasechnikov
S P
SP
Ozvinchuk
I I
II
Fedoruk
G V
GV
Drannik
G N
GN
D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000917:Antibody Formation / Q000187:drug effects; D003131:Combined Modality Therapy; D016207:Cytokines / Q000627:therapeutic use*; D004338:Drug Combinations; D004341:Drug Evaluation; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007370:Interferon Type I / Q000627:therapeutic use*; D008297:Male; D010587:Phagocytosis / Q000187:drug effects; D011182:Postoperative Care; D011704:Pyelonephritis / Q000276:immunology / Q000628:therapy*
D000276:Adjuvants, Immunologic; D016207:Cytokines; D004338:Drug Combinations; D007370:Interferon Type I; C062252:leukinferon