title: Recent solution structures of RNA and its complexes with drugs, peptides and proteins.
abstract: The past two years have seen remarkable progress in the study of RNA structure: the predicted era of RNA structural biology has arrived. Crystallographic structures of the hammerhead ribozyme and of a large subunit of a group I self-splicing intron have begun to reveal the structural basis of RNA enzymatic activity. A remarkable number of structures of small RNAs and of complexes with drugs, peptides and one protein domain have been determined by NMR.
authors.affiliation: MRC Laboratory of Molecular Biology, Cambridge, UK.
authors.forename: A
authors.initials: A
authors.lastname: Ramos
authors.forename: C C
authors.initials: CC
authors.lastname: Gubser
authors.forename: G
authors.initials: G
authors.lastname: Varani
mesh_terms: D005544:Forecasting; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D010455:Peptides / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*; D012313:RNA / Q000737:chemistry* / Q000378:metabolism*
chemical_list: D010455:Peptides; D004364:Pharmaceutical Preparations; D011506:Proteins; D012313:RNA