The effect of behavioural states on cerebral oxygenation during endotracheal suctioning of preterm babies.
Near infrared spectroscopy (NIRS) was used to investigate the effect of behavioural states on changes of oxygenated (O2Hb), deoxygenated haemoglobin (HHb) and total haemoglobin (tHb), during endotracheal suctioning. In an open prospective design, NIRS measurements have been done during 20 suctioning episodes in 13 preterm neonates. Heart rate, arterial oxygen saturation, and carbon dioxide tension were monitored continuously. Behavioural state (BS) observations were made and documented as well. The statistical analysis showed that in patients who were active, with crying periods during suctioning (behavioural states 4-5), changes of oxygenated (p < 0.005) and deoxygenated haemoglobin (p < 0.05), as well as of arterial oxygen saturation (p < 0.05) and heart rate (p < 0.05) were significantly greater than in patients who were quiet with predominant behavioural state 1, 2 and 3. These results underline the influence of behavioural states on the physiological answers to endotracheal suctioning. NIRS proved to be a valuable tool to evaluate possible harmful effects of different suctioning techniques.
Bernert
G
G
Department of Paediatrics and Neonatal Medicine, University Hospital Gasthuisberg, Leuven, Belgium.
von Siebenthal
K
K
Seidl
R
R
Vanhole
C
C
Devlieger
H
H
Casaer
P
P
D002560:Cerebrovascular Circulation / Q000502:physiology*; D003430:Cross-Sectional Studies; D006339:Heart Rate; D006454:Hemoglobins / Q000032:analysis*; D006801:Humans; D018730:Infant Behavior / Q000502:physiology*; D007231:Infant, Newborn; D007234:Infant, Premature; D015931:Intensive Care, Neonatal / Q000379:methods*; D007442:Intubation, Intratracheal / Q000379:methods; D008137:Longitudinal Studies; D009043:Motor Activity / Q000502:physiology*; D010100:Oxygen / Q000097:blood*; D010108:Oxyhemoglobins / Q000032:analysis; D011446:Prospective Studies; D019265:Spectroscopy, Near-Infrared; D013396:Suction / Q000009:adverse effects* / Q000379:methods
D006454:Hemoglobins; D010108:Oxyhemoglobins; D010100:Oxygen