Parenteral nutrition-associated cholestasis.
Parenteral nutrition-associated cholestasis is a persistent problem that has been a major cause of morbidity and mortality in young neonates. This review discusses some of the more recently associated risk factors, potential etiologies, including some potential genetic causes, and discusses potential forms of therapy, including the use of ursodeoxycholic acid and cholecystokinin.
Teitelbaum
D H
DH
University of Michigan Medical School, Section of Pediatric Surgery, Mott Children's Hospital, Ann Arbor 48109-0245, USA.
D018988:Bacterial Translocation; D002756:Cholagogues and Choleretics / Q000627:therapeutic use; D002766:Cholecystokinin / Q000627:therapeutic use; D002779:Cholestasis / Q000150:complications / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D007231:Infant, Newborn; D010289:Parenteral Nutrition, Total / Q000009:adverse effects*; D014580:Ursodeoxycholic Acid / Q000627:therapeutic use
D002756:Cholagogues and Choleretics; D014580:Ursodeoxycholic Acid; D002766:Cholecystokinin