Direct participation of phospholipids in transmembrane K(+)-transport.
The correlation between the characteristics of K(+)-transport across the mitochondrial and bilayer lipid membranes formed form mitochondrial lipids has been demonstrated. It has been shown that different modes of K(+)-efflux activation in mitochondria result in the appearance of K(+)-transporting phospholipid forms. The experiments described in this work suggest that current fluctuations similar to those observed for biological channels can be registered in unmodified bilayer lipid membranes containing no protein components.
Evtodienko YuV
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region.
Kudzina LuY
Medvedev
B I
BI
Yurkov
I S
IS
D000818:Animals; D001692:Biological Transport; D004553:Electric Conductivity; D007425:Intracellular Membranes / Q000378:metabolism* / Q000502:physiology; D008051:Lipid Bilayers / Q000378:metabolism*; D008567:Membranes, Artificial; D008928:Mitochondria / Q000378:metabolism* / Q000648:ultrastructure*; D010539:Permeability; D010743:Phospholipids / Q000378:metabolism*; D011188:Potassium / Q000378:metabolism*; D015221:Potassium Channels / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar
D008051:Lipid Bilayers; D008567:Membranes, Artificial; D010743:Phospholipids; D015221:Potassium Channels; D011188:Potassium