title: Effect of two anti-estrogens, clomiphene citrate and tamoxifen, on cervical mucus and sperm-cervical mucus interaction.
abstract: OBJECTIVE
  To compare the effect of two ovulation-inducing agents, clomiphene citrate and tamoxifen, on cervical mucus and sperm-cervical mucus interaction.
  
  
  METHODS
  Forty couples with unexplained infertility attending infertility clinic.
  
  
  METHODS
  Cervical mucus scoring and postcoital test done using the Moghissi system in a spontaneous cycle (control cycle) and with clomiphene citrate or tamoxifen (study cycles).
  
  
  RESULTS
  Clomiphene citrate significantly decreased cervical mucus production, whereas tamoxifen significantly improved the total score.
  
  
  CONCLUSIONS
  Tamoxifen is a better drug than clomiphene for ovulation induction in women with poor cervical mucus quality.
authors.affiliation: Department of Obstetrics and Gynaecology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: V
authors.initials: V
authors.lastname: Annapurna
authors.forename: L K
authors.initials: LK
authors.lastname: Dhaliwal
authors.forename: S
authors.initials: S
authors.lastname: Gopalan
mesh_terms: D000328:Adult; D002584:Cervix Uteri / Q000187:drug effects* / Q000502:physiology; D002996:Clomiphene / Q000494:pharmacology*; D004965:Estrogen Antagonists / Q000494:pharmacology*; D005260:Female; D005300:Fertility Agents, Female / Q000494:pharmacology*; D006801:Humans; D007246:Infertility / Q000188:drug therapy; D008297:Male; D009093:Mucus / Q000187:drug effects* / Q000502:physiology; D010062:Ovulation Induction; D011446:Prospective Studies; D013094:Spermatozoa / Q000187:drug effects* / Q000502:physiology; D013629:Tamoxifen / Q000494:pharmacology*
chemical_list: D004965:Estrogen Antagonists; D005300:Fertility Agents, Female; D013629:Tamoxifen; D002996:Clomiphene