Inositol treatment of autism.
Recent studies suggest that serotonin reuptake inhibitors are helpful in at least some symptoms of autism. Inositol is a precursor of the second messenger for some serotonin receptors, and has been reported effective in depression, panic disorder and obsessive-compulsive disorder. However a controlled double-blind crossover trial of inositol 200 mg/kg per day showed no benefit on 9 children with autism. Since biochemical studies could evaluate inositol in children already receiving serotonin reuptake inhibitors.
Levine
J
J
Abarbanel Mental Health Center, Bat Yam, Israel.
Aviram
A
A
Holan
A
A
Ring
A
A
Barak
Y
Y
Belmaker
R H
RH
D001321:Autistic Disorder / Q000188:drug therapy* / Q000523:psychology; D002648:Child; D002675:Child, Preschool; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007294:Inositol / Q000627:therapeutic use*; D008297:Male; D011569:Psychiatric Status Rating Scales
D007294:Inositol