title: Avian leukemias and lymphomas: interplay between retroviruses and herpesviruses.
abstract: Avian leukemias and lymphomas are caused primarily by retroviruses and herpesviruses. The protooncogenes activated by avian retroviral insertions in B & T-cell lymphomas will be summarized, with discussion on a new common insertion site, bravo, associated with RAV-O LTR insertion. Two novel interactions between avian retroviruses and Marek's disease herpesvirus (MDV) will be described: one involves direct interactions between putative viral oncoproteins and the other integrative recombination between these two viruses.
authors.affiliation: Department of Molecular Biology & Microbiology, Case Western Reserve University, School of Medicine, Cleveland, OH 44106, USA.
authors.forename: D
authors.initials: D
authors.lastname: Robinson
authors.forename: J L
authors.initials: JL
authors.lastname: Liu
authors.forename: D
authors.initials: D
authors.lastname: Jones
authors.forename: P
authors.initials: P
authors.lastname: Brunovskis
authors.forename: Z
authors.initials: Z
authors.lastname: Qian
authors.forename: R
authors.initials: R
authors.lastname: Isfort
authors.forename: J K
authors.initials: JK
authors.lastname: Tillotson
authors.forename: L
authors.initials: L
authors.lastname: Lee
authors.forename: R
authors.initials: R
authors.lastname: Witter
authors.forename: D
authors.initials: D
authors.lastname: Salter
authors.forename: L
authors.initials: L
authors.lastname: Crittenden
authors.forename: S
authors.initials: S
authors.lastname: Hughes
authors.forename: H J
authors.initials: HJ
authors.lastname: Kung
mesh_terms: D001355:Alpharetrovirus / Q000235:genetics; D000818:Animals; D001353:Avian Leukosis / Q000821:virology*; D002645:Chickens; D004251:DNA Transposable Elements; D006564:Herpesviridae / Q000235:genetics* / Q000472:pathogenicity; D007680:Kidney Neoplasms / Q000662:veterinary / Q000821:virology; D016393:Lymphoma, B-Cell / Q000662:veterinary* / Q000821:virology; D016399:Lymphoma, T-Cell / Q000662:veterinary* / Q000821:virology; D011201:Poultry Diseases; D011519:Proto-Oncogenes; D011995:Recombination, Genetic; D012190:Retroviridae / Q000235:genetics* / Q000472:pathogenicity; D014412:Tumor Virus Infections / Q000821:virology; D016662:Virus Integration; D009396:Wilms Tumor / Q000662:veterinary / Q000821:virology
chemical_list: D004251:DNA Transposable Elements