title: Precision of the gallbladder ejection fraction obtained with Tc-99m-pyridoxyl-5-methyl-tryptophan (99mTc-PMT) hepatobiliary scintigraphy as compared with the contraction ratio in three-dimensional computed tomography.
abstract: The gallbladder ejection fraction (GBEF) obtained with Tc-99m-pyridoxyl-5-methyl-tryptophan (99mTc-PMT) hepatobiliary scintigraphy has been used as a parameter of gallbladder function. To determine the accuracy of GBEF, the relationship with the contraction ratio of the gallbladder (GBCR) obtained with three-dimensional helical computed tomography (3D-CT) was studied.
  
  
  METHODS
  A normal volunteer, 8 patients suffering from cholecystolithiasis and a patient with gallbladder dyskinesia were examined. The percent initial dose (%ID) for the gallbladder and GBEF with hepatobiliary scintigraphy were used to compare the volume of the gallbladder and GBCR which was measured by 3D-CT.
  
  
  RESULTS
  The %ID of the gallbladder was correlated with the volume of the gallbladder by 3D-CT (Y = 1.000X - 1.818, r = 0.928). GBEF was correlated well with GBCR by 3D-CT (Y = 0.916X + 6.296, r = 0.975).
  
  
  CONCLUSIONS
  The %ID of the gallbladder obtained with hepatobiliary scintigraphy may be a good indicator of the volume of the gallbladder. The accuracy of GBEF was confirmed by comparison with 3D-CT examination. GBEF is considered a useful parameter of pathophysiological gallbladder function.
authors.affiliation: Department of Radiology, Showa University Fujigaoka Hospital, Yokohama, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Uchiyama
authors.forename: Y
authors.initials: Y
authors.lastname: Kuniyasu
authors.forename: S T
authors.initials: ST
authors.lastname: Higashi
authors.forename: Y
authors.initials: Y
authors.lastname: Shen
authors.forename: Y
authors.initials: Y
authors.lastname: Niio
authors.forename: S
authors.initials: S
authors.lastname: Hasebe
authors.forename: S
authors.initials: S
authors.lastname: Matsuoka
authors.forename: H
authors.initials: H
authors.lastname: Shima
authors.forename: H
authors.initials: H
authors.lastname: Shinohara
authors.forename: K
authors.initials: K
authors.lastname: Takizawa
authors.forename: M
authors.initials: M
authors.lastname: Obuchi
authors.forename: M
authors.initials: M
authors.lastname: Honda
authors.forename: N
authors.initials: N
authors.lastname: Hirata
mesh_terms: D000328:Adult; D000368:Aged; D002765:Cholecystography / Q000379:methods*; D002769:Cholelithiasis / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging* / Q000502:physiology; D005705:Gallbladder Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology; D016473:Gallbladder Emptying; D006801:Humans; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011759:Pyrrolidines; D011877:Radionuclide Imaging; D013752:Tetracycline; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D015609:Organotechnetium Compounds; D011759:Pyrrolidines; C057732:technetium Tc 99m pyrrolidino-methyltetracycline; D013752:Tetracycline