Exceptionally potent antispermatogenic compounds from 8-halogenation of (4aRS,5SR,9bRS)-hexahydroindeno-[1,2-c]pyridines.
Cook
C E
CE
Chemistry and Life Sciences, Research Triangle Institute, Research Triangle Park, North Carolina 27709, USA.
Jump
J M
JM
Zhang
P
P
Stephens
J R
JR
Lee
Y W
YW
Fail
P A
PA
Anderson
S A
SA
D000284:Administration, Oral; D000818:Animals; D003272:Contraceptive Agents, Male / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D005298:Fertility / Q000187:drug effects; D007192:Indenes / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D008297:Male; D051379:Mice; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013091:Spermatogenesis / Q000187:drug effects*; D013237:Stereoisomerism
D003272:Contraceptive Agents, Male; D007192:Indenes; D011725:Pyridines