title: [Granular cell tumor of the eyelid].
abstract: A 54-year-old woman was evaluated for a right lower eyelid lesion that had been present for four months. Examination showed a firm, yellow to brown mass with associated loss of eyelashes. A complete resection of the lesion was performed and the lid was reconstructed with the Hughes procedure. Histologic features of the excised mass were consistent with a granular cell tumor. Immunohistochemical stains were positive for S-100 protein, neuron specific enolase, laminin, and various myelin proteins in the tumor cells. Ultrastructural examination displayed that tumor cells were distended by autophagic granules and some cells contained angulated bodies (Bangle bodies). Granular cell tumors probably origin from Schwann cells and rarely involve the eyelids.
authors.affiliation: L. F. Montgomery Eye Pathology Laboratory, Emory Eye Center, Emory University School of Medicine Atlanta, GA, USA.
authors.forename: C W
authors.initials: CW
authors.lastname: Spraul
authors.forename: T H
authors.initials: TH
authors.lastname: Wojno
authors.forename: H E
authors.initials: HE
authors.lastname: Grossniklaus
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D005142:Eyelid Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005143:Eyelids / Q000473:pathology / Q000601:surgery; D005260:Female; D016586:Granular Cell Tumor / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D002479:Inclusion Bodies / Q000648:ultrastructure; D008854:Microscopy, Electron; D008875:Middle Aged
chemical_list: D014408:Biomarkers, Tumor