title: Massive pleural effusion in diffuse granulomatous disease.
abstract: Although recurrent, massive pleural effusions frequently are associated with malignancy, they rarely occur in granulomatous diseases of the lung. We report the case of a 50-year-old man with a recurrent, massive pleural effusion and a diffuse granulomatous disease that involved the lung, the lymphatics, and bone marrow. The cause of the effusion and granulomatous disease is not entirely clear; however, the effusion did resolve with antifungal therapy and a brief course of corticosteroids.
authors.affiliation: Division of Pulmonary, Critical Care, and Occupational Medicine, the University of Iowa College of Medicine, and the Iowa City Veterans Administration Medical Center, IA 52242, USA.
authors.forename: A B
authors.initials: AB
authors.lastname: Carter
authors.forename: G W
authors.initials: GW
authors.lastname: Hunninghake
mesh_terms: D001853:Bone Marrow / Q000473:pathology; D006099:Granuloma / Q000150:complications* / Q000175:diagnosis / Q000382:microbiology; D006660:Histoplasmosis / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008168:Lung / Q000473:pathology; D008172:Lung Diseases, Fungal / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D010996:Pleural Effusion / Q000175:diagnosis / Q000209:etiology*; D012008:Recurrence; D014057:Tomography, X-Ray Computed