[The effect of dimethylethanolamine on the summation capacity of the central nervous system and on the work capacity of animals in a chronic experiment].
The effects of inhaling action of dimethylethanolamine (twenty-four-hour for four months (on summarizing liminal index, SLI) and efficiency of white rats in dependence on various concentrations of amino alcohol were studied in chronic experiments. The obtained results allowed to conclude, that high (2.76 mg/m3) concentration of dimethylethanolamine influenced on functional state of central nervous system. SLI changes pointed to disturbance of dynamic equilibrium between processes of inhibition and excitation with prevalence of latter. In the same time the sufficient grounds for the attribution of dimethylethanolamine to myorelaxants were absent, since in our experiments we used only very high concentrations of this agent.
Lukoshko
S O
SO
Koval'chuk
T O
TO
Rybal'chenko
V K
VK
D000280:Administration, Inhalation; D000818:Animals; D000928:Antidepressive Agents / Q000008:administration & dosage / Q000494:pharmacology*; D002490:Central Nervous System / Q000502:physiology*; D003642:Deanol / Q000008:administration & dosage / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D005260:Female; D051381:Rats; D013997:Time Factors
D000928:Antidepressive Agents; D003642:Deanol