Behaviour disorder in an adolescent with terminal deletion of chromosome 3.
Individuals with terminal deletion of the long arm of chromosome 3 are rare and survival into adulthood has not been previously reported. A 15-year-old with this condition was studied and the difficulties in management of the manifest behaviours are described. This chromosomal abnormality may be associated with mental and functional deterioration as well as severe self-injurious behaviour, commencing in early childhood.
Davies
J L
JL
Psychiatric Unit, Barnet General Hospital, Herts, England.
Mathew
G
G
D000203:Activities of Daily Living / Q000523:psychology; D000293:Adolescent; D000374:Aggression / Q000523:psychology; D002869:Chromosome Aberrations / Q000235:genetics*; D002872:Chromosome Deletion; D025063:Chromosome Disorders; D002893:Chromosomes, Human, Pair 3; D019465:Craniofacial Abnormalities / Q000175:diagnosis / Q000235:genetics / Q000523:psychology; D006801:Humans; D008607:Intellectual Disability / Q000175:diagnosis / Q000235:genetics* / Q000523:psychology; D008297:Male; D011595:Psychomotor Agitation / Q000235:genetics* / Q000517:prevention & control / Q000523:psychology; D012112:Residential Facilities; D016728:Self-Injurious Behavior / Q000235:genetics* / Q000517:prevention & control / Q000523:psychology