FasL--too much of a good thing? Transplanted grafts of pancreatic islet cells engineered to express Fas ligand are destroyed not protected by the immune system.
Lau
H T
HT
Stoeckert
C J
CJ
D000818:Animals; D017690:Cell Transplantation; D003921:Diabetes Mellitus, Experimental / Q000276:immunology; D053222:Fas Ligand Protein; D005818:Genetic Engineering; D007515:Islets of Langerhans / Q000166:cytology / Q000276:immunology*; D008562:Membrane Glycoproteins / Q000235:genetics / Q000276:immunology*; D051379:Mice; D008822:Mice, Transgenic; D009504:Neutrophils / Q000276:immunology; D014181:Transplantation Immunology
D053222:Fas Ligand Protein; C505658:Fasl protein, mouse; D008562:Membrane Glycoproteins