title: Percutaneous transluminal balloon pulmonary valvuloplasty using domestic balloon catheter for congenital pulmonary valve stenosis in children.
abstract: OBJECTIVE
  To estimate the effect of percutaneous balloon pulmonary valvuloplasty (PBPV) using domestic balloon catheter for congenital pulmonary valve stenosis (PVS) in infants and children.
  
  
  METHODS
  The data of 70 patients aged from 1.5 to 12 years (mean 5.5 +/- 3.4 years) who underwent PBPV using domestic balloon catheter for PVS in our institution were reviewed. Sixty-six patients had dome-shaped valve stenosis, and 4 had displastic valve stenosis. SaO2 reduced in 5 patients and associated open foramen ovale was noted in 23. Predilatation, right ventricular systolic pressure ranged from 60 to 234 mmHg (mean 115.75 +/- 36.15 mmHg). The systolic gradient (delta P) from right ventricle to pulmonary artery was 89.92 +/- 38.25 mmHg. Balloon diameter was selected 120%-142% of pulmonary valve annulus diameter (mean 132%). All patients were followed up for 3 months-4 years by means of clinical examination. ECG, 2D-UCG, and Doppler-UCG.
  
  
  RESULTS
  After dilatation, delta P reduced from 89.92 +/- 38.25 to 14.65 +/- 11.40 mmHg (P < 0.001). The rate of decrease in transvalve gradient (delta P) was 83.7%. No patients experienced procedure-related events. Mid-term follow-up showed that no patients had clinical and instrumental complications. Doppler and ECG analyses showed that delta P did not change significantly similar to immediate gradient after PBPV and right ventricular hypertrophy disappeared progressively 6 months after PBPV.
  
  
  CONCLUSIONS
  PBPV is a useful, safe and definitive procedure in the treatment of isolated PVS in infants and children. The properties and features of the balloon catheter produced by Shanghai Med-Tech Factory are similar to those of Med-Tech balloon catheter of U.S.A.
authors.affiliation: Affiliated Children Hospital, Zhejiang Medical University, Hangzhou.
authors.forename: C
authors.initials: C
authors.lastname: Xia
authors.forename: M
authors.initials: M
authors.lastname: Kang
authors.forename: W
authors.initials: W
authors.lastname: Zhu
authors.forename: J
authors.initials: J
authors.lastname: Wang
authors.forename: D
authors.initials: D
authors.lastname: Bao
authors.forename: Y
authors.initials: Y
authors.lastname: Zhou
authors.forename: F
authors.initials: F
authors.lastname: Gong
mesh_terms: D002404:Catheterization; D002648:Child; D002675:Child, Preschool; D015150:Echocardiography, Doppler; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D011666:Pulmonary Valve Stenosis / Q000151:congenital / Q000628:therapy*