A Staphylococcus aureus enterotoxin-B induced type 1 immediate hypersensitivity reaction in a goat.
A Nigerian dwarf goat intended for the production of antibodies to staphylococcal enterotoxin-B exhibited classical signs of a type 1 anaphylactic reaction 2 to 3 min after parenteral introduction of this antigen. The exquisite sensitivity demonstrated in concert with the pathognomonic signs appeared to make the breed and species an excellent model for the further study and interpretation of this syndrome in domestic food animals.
Schofield
L N
LN
Medical Countermeasures Section, Defence Research Establishment Suffield, Alberta, Canada.
DiNinno
V L
VL
Bhatti
A R
AR
D000707:Anaphylaxis / Q000188:drug therapy / Q000276:immunology / Q000662:veterinary*; D000818:Animals; D004768:Enterotoxins / Q000008:administration & dosage / Q000276:immunology*; D004837:Epinephrine / Q000627:therapeutic use; D015511:Goat Diseases / Q000276:immunology*; D006041:Goats; D011239:Prednisolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D013211:Staphylococcus aureus / Q000276:immunology*; D018089:Superantigens / Q000008:administration & dosage / Q000276:immunology*
D004768:Enterotoxins; D018089:Superantigens; C031818:enterotoxin B, staphylococcal; D011239:Prednisolone; C021322:prednisolone hemisuccinate; D004837:Epinephrine