Stealth virus epidemic in the Mohave Valley. I. Initial report of virus isolation.
Increasing numbers of patients within the Mohave Valley region of the United States are reporting symptoms attributable to atypical neurological illness. Many of these patients have experienced an acute-onset gastrointestinal illness during the spring and summer of 1996. Stealth viral cultures performed on the blood of 40 of these patients have been uniformly positive, yielding unequivocal transmissible cytopathic effect (CPE) in both human- and monkey-derived cell lines. One patient has died from a stealth-CPE-positive glioblastoma, while another patient has developed a plemorphic adenoma of the parotid. Viral cultures and epidemiological data support human-to-human, and probable human-to-dog, transmission of the Mohave stealth virus infection.
Martin
W J
WJ
Center for Complex Infectious Diseases, Rosemead, Calif 91770, USA. wjmartin@bcf.usc.edu
Anderson
D
D
D000818:Animals; D001130:Arizona; D003587:Cytomegalovirus / Q000472:pathogenicity*; D003586:Cytomegalovirus Infections / Q000473:pathology / Q000821:virology*; D003588:Cytopathogenic Effect, Viral; D004196:Disease Outbreaks; D004285:Dogs