[A clinico-pharmacological study of olifen in periodontal inflammation].
Clinical study of the efficacy of oliphen treatment in generalized periodontitis in comparison with galascorbin treatment was conducted. Oliphen arrested the inflammatory process in the periodontium quickly and effectively and shortened the duration of treatment by half. Under its effect lipid peroxidation became less intense, the level of malonic dealdehyde decreased, and the activity of catalase in the oral fluid of patients with periodontitis increased. The favorable effect of oliphen in periodontitis is connected with its antioxidant and antihypoxant properties.
Turgeneva
L B
LB
Novikov
V E
VE
Tsenov
L M
LM
D000328:Adult; D000975:Antioxidants / Q000494:pharmacology* / Q000627:therapeutic use; D001205:Ascorbic Acid / Q000494:pharmacology / Q000627:therapeutic use; D002908:Chronic Disease; D004338:Drug Combinations; D004341:Drug Evaluation; D005419:Flavonoids / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D047348:Hydrolyzable Tannins; D015227:Lipid Peroxidation / Q000187:drug effects; D008163:Luminescent Measurements; D008875:Middle Aged; D010518:Periodontitis / Q000188:drug therapy* / Q000378:metabolism; D010519:Periodontium / Q000187:drug effects; D010647:Phenyl Ethers / Q000494:pharmacology* / Q000627:therapeutic use; D012463:Saliva / Q000187:drug effects / Q000378:metabolism; D012996:Solutions; D013634:Tannins / Q000494:pharmacology / Q000627:therapeutic use
D000975:Antioxidants; D004338:Drug Combinations; D005419:Flavonoids; D047348:Hydrolyzable Tannins; D010647:Phenyl Ethers; D012996:Solutions; D013634:Tannins; C085806:olifen; C002944:galascorbin; D001205:Ascorbic Acid