title: Functional aspects of Aujeszky's disease (pseudorabies) viral proteins with relation to invasion, virulence and immunogenicity.
abstract: In the present review, the interaction of Aujeszky's disease (pseudorabies) virus (ADV) with individual susceptible cells and the entire host is presented. Special emphasis is put on how viral envelope glycoproteins control invasion and virulence. Furthermore, the importance of envelope glycoproteins in the induction of a protective immunity is discussed.
authors.affiliation: Laboratory of Veterinary Virology, Faculty of Veterinary Medicine, University of Gent, Merelbeke, Belgium.
authors.forename: H J
authors.initials: HJ
authors.lastname: Nauwynck
mesh_terms: D000818:Animals; D011558:Herpesvirus 1, Suid / Q000276:immunology / Q000472:pathogenicity* / Q000502:physiology*; D011557:Pseudorabies / Q000276:immunology / Q000503:physiopathology*; D022421:Pseudorabies Vaccines; D013552:Swine; D014759:Viral Envelope Proteins / Q000276:immunology / Q000502:physiology*; D014765:Viral Vaccines; D014774:Virulence
chemical_list: D022421:Pseudorabies Vaccines; D014759:Viral Envelope Proteins; D014765:Viral Vaccines