title: Immunohistochemical localization of calbindin D28k in the periodontal Ruffini endings of rat incisors.
abstract: It was examined whether calbindin D28k (CB) might be located in the rat incisor periodontal Ruffini ending, an essential mechanoreceptor in periodontal ligament, by light- and electron-microscopic immunohistochemistry. Some thick nerve fibers showing CB-like immunoreactivity (LI) entered the lingual half of the periodontal ligament of the incisor and showed the dendritic terminal arborization. Electron-dense immunoreaction products indicating CB-LI were distributed diffusely in axoplasm of the axon terminals, no mitochondria, however, were not labeled. Neither cell bodies nor cytoplasmic extensions of the terminal Schwann cells exhibited CB-LI. CB was presumed to be involved in the maintenance of Ca2+ homeostasis in the mechano-electric transduction in mechanoreceptors in the periodontal ligament.
authors.affiliation: Department of Oral Anatomy, Niigata University School of Dentistry, Gakkocho-dori, Japan. ochi@dent.niigata-u.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Ochi
authors.forename: S
authors.initials: S
authors.lastname: Wakisaka
authors.forename: S H
authors.initials: SH
authors.lastname: Youn
authors.forename: K
authors.initials: K
authors.lastname: Hanada
authors.forename: T
authors.initials: T
authors.lastname: Maeda
mesh_terms: D000818:Animals; D064092:Calbindin 1; D064026:Calbindins; D005881:Gingiva / Q000294:innervation*; D007150:Immunohistochemistry; D007180:Incisor / Q000294:innervation*; D008297:Male; D008465:Mechanoreceptors / Q000502:physiology; D008854:Microscopy, Electron; D016253:Microscopy, Immunoelectron; D009411:Nerve Endings / Q000502:physiology* / Q000648:ultrastructure; D009412:Nerve Fibers / Q000648:ultrastructure; D051381:Rats; D017207:Rats, Sprague-Dawley; D064030:S100 Calcium Binding Protein G / Q000378:metabolism*
chemical_list: C576500:Calb1 protein, rat; D064092:Calbindin 1; D064026:Calbindins; D064030:S100 Calcium Binding Protein G