title: Secreted enzymes of Aeromonas.
abstract: A hallmark characteristic of species of Aeromonas is their ability to secrete a wide variety of enzymes associated with pathogenicity and environmental adaptability. Among the most intensively studied are beta-lactamases, lipases, hemolytic enterotoxins, proteases, chitinases, nucleases and amylases. Multiple copies of genes encoding each type of enzyme provide additional biological diversity. Except for the chitinases, these multiple copies show little evolutionary relatedness at the DNA level and only limited similarity at the protein level. Indeed a number of the genes, such as nuclease H of A. hydrophila, have no similarity to known prokaryotic or eukaryotic sequences. The challenge is to determine how these genes evolved, where they originated and why Aeromonas possesses them in such abundance and variety.
authors.affiliation: Department of Microbiology, University of Queensland, St. Lucia, Australia. pemberto@biosci.uq.oz.au
authors.forename: J M
authors.initials: JM
authors.lastname: Pemberton
authors.forename: S P
authors.initials: SP
authors.lastname: Kidd
authors.forename: R
authors.initials: R
authors.lastname: Schmidt
mesh_terms: D000333:Aeromonas / Q000201:enzymology* / Q000472:pathogenicity; D000681:Amylases / Q000502:physiology; D002688:Chitinases / Q000502:physiology; D003851:Deoxyribonucleases / Q000502:physiology; D010450:Endopeptidases / Q000502:physiology; D008049:Lipase / Q000502:physiology; D017262:Siderophores / Q000502:physiology; D001618:beta-Lactamases / Q000502:physiology
chemical_list: D017262:Siderophores; D003851:Deoxyribonucleases; D008049:Lipase; D000681:Amylases; D002688:Chitinases; D010450:Endopeptidases; D001618:beta-Lactamases