title: In vivo pharmacokinetics of phosphorothioate oligonucleotides containing contiguous guanosines.
authors.affiliation: Hybridon, Inc., Cambridge, MA 02139, USA.
authors.forename: S
authors.initials: S
authors.lastname: Agrawal
authors.forename: W
authors.initials: W
authors.lastname: Tan
authors.forename: Q
authors.initials: Q
authors.lastname: Cai
authors.forename: X
authors.initials: X
authors.lastname: Xie
authors.forename: R
authors.initials: R
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001483:Base Sequence; D004355:Drug Stability; D005243:Feces / Q000737:chemistry; D006151:Guanosine; D008297:Male; D008657:Metabolic Clearance Rate; D016376:Oligonucleotides, Antisense / Q000097:blood / Q000737:chemistry / Q000493:pharmacokinetics* / Q000652:urine; D051381:Rats; D017207:Rats, Sprague-Dawley; D013873:Thionucleotides / Q000097:blood / Q000737:chemistry / Q000493:pharmacokinetics* / Q000652:urine; D014018:Tissue Distribution
chemical_list: D016376:Oligonucleotides, Antisense; D013873:Thionucleotides; D006151:Guanosine