Acute peripheral neuropathy in adults. Guillain-Barré syndrome and related disorders.
Acute paralysis in adults has an extensive assortment of etiologies. Guillian-Barré syndrome is the most common cause of acute neuropathy in adults. This review emphasizes pathophysiology, clinical features, differential diagnosis, and a practical approach to the laboratory work-up for patients with suspected Guillian-Barré syndrome. The current status of immunotherapy is reviewed.
Pascuzzi
R M
RM
Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.
Fleck
J D
JD
D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D000328:Adult; D003422:Critical Care; D006801:Humans; D007116:Immunization, Passive; D010523:Peripheral Nervous System Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D010951:Plasma Exchange; D011115:Polyneuropathies / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D011129:Polyradiculoneuropathy / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
D000305:Adrenal Cortex Hormones