title: Aplastic anemia complicating Sjögren's syndrome.
abstract: A 47-year-old woman was referred to our hospital because of severe anemia and polyclonal gammopathy. She developed sicca syndrome after admission. Laboratory data revealed pancytopenia (white blood cells, 2,800/microliter; hemoglobin, 6.4 g/dl; platelets, 6.1 x 10(4)/microliter) and hyper gamma globulinemia (5.2 g/dl), and bone marrow was hypoplastic. Histology of the salivary gland showed infiltration of lymphocytes. We report a good response to immunosuppressive therapy in a rare case of aplastic anemia complicating Sjögren's syndrome.
authors.affiliation: First Department of Internal Medicine, Kansai Medical University, Osaka.
authors.forename: N
authors.initials: N
authors.lastname: Matsumoto
authors.forename: H
authors.initials: H
authors.lastname: Kagawa
authors.forename: H
authors.initials: H
authors.lastname: Ichiyoshi
authors.forename: T
authors.initials: T
authors.lastname: Iguchi
authors.forename: Y
authors.initials: Y
authors.lastname: Yamanaka
authors.forename: Y
authors.initials: Y
authors.lastname: Kishimoto
authors.forename: S
authors.initials: S
authors.lastname: Fukuhara
mesh_terms: D000741:Anemia, Aplastic / Q000150:complications* / Q000188:drug therapy / Q000209:etiology; D005260:Female; D006801:Humans; D006942:Hypergammaglobulinemia / Q000150:complications / Q000188:drug therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000150:complications* / Q000188:drug therapy
chemical_list: D007166:Immunosuppressive Agents; D008775:Methylprednisolone