Is the cholesterol-lowering effect of simvastatin influenced by CYP2D6 polymorphism?
Nordin
C
C
Dahl
M L
ML
Eriksson
M
M
Sjöberg
S
S
D000924:Anticholesteremic Agents / Q000378:metabolism*; D002784:Cholesterol / Q000097:blood*; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics*; D003647:Debrisoquin / Q000378:metabolism; D004791:Enzyme Inhibitors / Q000378:metabolism*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D008148:Lovastatin / Q000031:analogs & derivatives* / Q000378:metabolism; D008297:Male; D011110:Polymorphism, Genetic; D019821:Simvastatin
D000924:Anticholesteremic Agents; D004791:Enzyme Inhibitors; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D002784:Cholesterol; D008148:Lovastatin; D019821:Simvastatin; D019389:Cytochrome P-450 CYP2D6; D003647:Debrisoquin