Less can be more--at least in mice: osteocalcin deficiency associated with increased bone formation.
Holbauer
L C
LC
Endocrine Research Unit, Mayo Clinic, Rochester, Minnesota, USA.
Heufelder
A E
AE
D000818:Animals; D015519:Bone Density; D001842:Bone and Bones / Q000033:anatomy & histology / Q000378:metabolism; D051379:Mice / Q000033:anatomy & histology / Q000378:metabolism / Q000502:physiology*; D008817:Mice, Mutant Strains / Q000033:anatomy & histology / Q000378:metabolism; D015675:Osteocalcin / Q000172:deficiency*; D010012:Osteogenesis / Q000502:physiology*
D015675:Osteocalcin