Transcranial magnetic stimulation induces alterations in brain monoamines.
Transcranial magnetic stimulation has been suggested as a possible therapeutic tool in depression. In behavioral models of depression, magnetic stimulation induced similar effects to those of electroconvulsive shock. This study demonstrates the effect of a single session of rapid TMS on tissue monoamines in rat brain. Alterations in monoamines were selective and specific in relation to brain areas and type of monoamine. The results imply on a biochemical basis to the suggested ECT-like treatment potential of TMS.
Ben-Shachar
D
D
Faculty of Medicine, Technion, Department of Psychiatry, Rambam Medical Center, Beer-Sheva, Israel.
Belmaker
R H
RH
Grisaru
N
N
Klein
E
E
D000818:Animals; D015306:Biogenic Monoamines / Q000378:metabolism*; D001921:Brain / Q000502:physiology*; D001923:Brain Chemistry / Q000528:radiation effects*; D004574:Electromagnetic Fields; D008297:Male; D010812:Physical Stimulation; D051381:Rats; D017207:Rats, Sprague-Dawley
D015306:Biogenic Monoamines