title: Abnormal Tl-201 myocardial scintigraphy associated with administration of sodium aurothiomalate.
abstract: A patient with strikingly reduced Tl-201 myocardial retention after intramuscular administration of gold therapy (sodium aurothiomalate) is described. Following a routine Bruce protocol exercise test, postexercise scintigraphy was normal; an abnormal scan of the thorax was obtained on delayed imaging at 3 hours. This scan showed no demonstrable myocardial retention of tracer. In between the two acquisitions, the patient received 50 mg intramuscular sodium aurothiomalate for rheumatoid arthritis. A repeat scan obtained 3 days later showed a normal myocardial scintigram. It is recommended that patients receiving intramuscular gold therapy should not undergo such treatment close to the timing of Tl-201 myocardial scans.
authors.affiliation: Division of Nuclear Medicine, University of Michigan Medical Center, Ann Arbor, USA.
authors.forename: K C
authors.initials: KC
authors.lastname: Allman
authors.forename: N
authors.initials: N
authors.lastname: Petry
authors.forename: B
authors.initials: B
authors.lastname: Shapiro
mesh_terms: D018501:Antirheumatic Agents / Q000494:pharmacology*; D006052:Gold Sodium Thiomalate / Q000494:pharmacology*; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013794:Thallium Radioisotopes
chemical_list: D018501:Antirheumatic Agents; D013794:Thallium Radioisotopes; D006052:Gold Sodium Thiomalate