[Glucagonoma: case report and literature review].
Glucagonoma is a neuroendocrine tumor of pancreatic alpha cells manifested by necrolytic migratory erythema, hyperglucagonemia, glucose intolerance, weight loss, anemia and hypopaminoacidemia. We report a case of glucagonoma in a 38 years-old patient diagnosed by the presence of a pancreatic tumor, liver metastasis, weight loss, glucose intolerance, necrolytic migratory erythema, hyperglucagonemia (1400 pg/ml; normal < 200 pg/ml) and histologic demonstration of glucagon and neurospecific enolase by immunocytochemical reaction. Actual therapeutic of glucagonoma includes surgery, chemotherapy, somatostatin or octreotide for control of the symptoms, and more recently alpha-interferon was suggested.
das Neves
M M
MM
UNIFESP-EPM.
Martins Júnior
E V
EV
Gaburri
A K
AK
Chebli
J M
JM
Stávale
J N
JN
Herani Filho
A K
AK
D000328:Adult; D005935:Glucagonoma / Q000473:pathology* / Q000556:secondary; D006801:Humans; D008297:Male; D010190:Pancreatic Neoplasms / Q000473:pathology*