An evaluation of neuromuscular reversal with edrophonium in a patient with malathion intoxication.
We evaluated the neuromuscular reversal with edrophonium using peripheral nerve stimulator and recorder in a patient with malathion intoxication. Edrophonium 10 mg i.v. caused an increase in single twitch tension by 76% of the control during the recovery phase from an acute cholinergic crisis 16 days after ingestion of malathion solution. The present study indicated that edrophonium test seems to be a reliable monitoring in evaluating neuromuscular reversal in the patient with acute malathion insecticide poisoning.
Matsukawa
S
S
Division of Intensive Care Medicine, Tohoku University Hospital, Sendai, Japan.
Hashimoto
Y
Y
Kato
M
M
Hoshi
K
K
Satoh
D
D
Horinouchi
T
T
Satoh
S
S
Saishu
T
T
D000328:Adult; D002800:Cholinesterase Inhibitors / Q000506:poisoning*; D004491:Edrophonium; D004558:Electric Stimulation; D005260:Female; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D008294:Malathion / Q000506:poisoning*; D008991:Monitoring, Physiologic; D009119:Muscle Contraction / Q000187:drug effects; D009469:Neuromuscular Junction / Q000187:drug effects* / Q000503:physiopathology*; D010525:Peripheral Nerves / Q000187:drug effects* / Q000503:physiopathology*; D013406:Suicide, Attempted
D002800:Cholinesterase Inhibitors; D007306:Insecticides; D004491:Edrophonium; D008294:Malathion