title: Successful pregnancy following zygote intrafallopian transfer for congenital cervical hypoplasia.
abstract: BACKGROUND
  Congenital cervical atresia and hypoplasia are rare abnormalities that generally require reconstructive or extirpative procedures to relieve outflow tract obstruction. Infertility is a common sequel, and only four previous pregnancies have been reported. In selected cases, zygote intrafallopian transfer (ZIFT) or other assisted reproductive techniques may offer alternatives for conception.
  
  
  METHODS
  A 21-year-old amenorrheic woman experienced a spontaneous gush of vaginal bleeding following an 11-year history of cyclic lower abdominal pain. Regular but prolonged and painful menses ensued. After another 8 years of primary infertility, transcervical and transfundal hysteroscopy demonstrated congenital cervical hypoplasia and a normal endometrial cavity. Conception was achieved during her third cycle of ZIFT. Delivery occurred by elective cesarean at 39 weeks for a persistent oblique fetal lie.
  
  
  CONCLUSIONS
  A successful pregnancy was established following ZIFT in a woman with congenital cervical hypoplasia. The endometrial cavity was evaluated by a previously unreported technique, transfundal hysteroscopy. The use of appropriate surgical or assisted reproductive techniques in conjunction with individualized post-conception management may permit successful pregnancy and delivery in selected women with congenital cervical hypoplasia and atresia.
authors.affiliation: Department of Obstetrics and Gynecology, University of British Columbia, Vancouver, Canada.
authors.forename: M R
authors.initials: MR
authors.lastname: Fluker
authors.forename: M W
authors.initials: MW
authors.lastname: Bebbington
authors.forename: M G
authors.initials: MG
authors.lastname: Munro
mesh_terms: D000328:Adult; D002584:Cervix Uteri / Q000002:abnormalities*; D005260:Female; D006801:Humans; D011247:Pregnancy; D017388:Zygote Intrafallopian Transfer