Quantitative assessment of feline epidermal Langerhans cells.
The densities of feline epidermal dendritic cells expressing CD18, MHC class II and CD1a antigens were determined for four anatomical locations in 19 cats of European breed in blind conditions. The densities (+/- SD) of CD1a+ Langerhans cells in the skin of the abdominal wall (269 +/- 68 cells/mm2), the back (363 +/- 19), the internal side of the ear (572 +/- 30) and the external side of the ear (502 +/- 32) were significantly different, with young and old animals displaying less stained cells than adults. No significant differences in the mean densities were found with regard to sex, colour or antibody used.
Saint-André Marchal
I
I
Department de Pathologie et Clinique des Carnivores Domestiques, Ecole Nationale Vetérinaire de Lyon, Marcy I'Etoile, France.
Dezutter-Dambuyant
C
C
Martin
J P
JP
Willett
B J
BJ
Woo
J C
JC
Moore
P F
PF
Magnol
J P
JP
Schmitt
D
D
Marchal
T
T
D000005:Abdomen; D000375:Aging / Q000276:immunology*; D000818:Animals; D001415:Back; D002415:Cats / Q000276:immunology*; D002452:Cell Count; D004431:Ear, External; D000078404:Epidermal Cells; D005260:Female; D015395:Histocompatibility Antigens Class I / Q000032:analysis*; D007150:Immunohistochemistry; D007801:Langerhans Cells / Q000166:cytology* / Q000276:immunology*; D008297:Male
D015395:Histocompatibility Antigens Class I