title: Yucatan pig: an optimal hairless model for a true random cutaneous flap.
abstract: Porcine models have been used extensively for skin flap research because of the established similarity between the cutaneous blood supply of the swine and humans. The Yucatan minipig provides an excellent model for researching the properties of random cutaneous flaps, offering several advantages over other breeds of swine. In this study, a total of 67 random cutaneous dorsal flank flaps measuring 4 x 14 cm were raised on nine Yucatan minipigs. The mean survival length (10.03 +/- 1.60 cm) of the nondelayed flaps was greater than others reported in the literature. The well-defined plane between the subcutaneous tissue and the panniculus carnosus facilitated flap elevation consistently above the level of the panniculus carnosus thereby ensuring the creation of a true random cutaneous flap. Furthermore, the hairless nature of the skin, particularly beneficial in studying chemical peels, permits easy visualization and monitoring of any external skin changes. These advantages make the Yucatan minipig a more desirable alternative to other breeds of swine for use in skin flap research.
authors.forename: L
authors.initials: L
authors.lastname: DeLuca
authors.forename: M
authors.initials: M
authors.lastname: Beckenstein
authors.forename: B
authors.initials: B
authors.lastname: Guyuron
mesh_terms: D000818:Animals; D006085:Graft Survival; D006801:Humans; D008954:Models, Biological; D009336:Necrosis; D012867:Skin / Q000473:pathology; D013524:Surgical Flaps / Q000473:pathology; D013552:Swine; D013556:Swine, Miniature