title: Prostaglandins in liver disease and liver transplantation.
abstract: This brief review summarizes the physiology and pharmacology of eicosanoids and describes how they have been tested for possible application in liver disease and transplantation. The objective is to trace the stepwise application from the laboratory to the bedside. Although many questions remain to be answered, the observations summarized in this article have opened up new and potentially rewarding prospects in application to liver disease.
authors.affiliation: The Upjohn Company, Kalamazoo, Michigan, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Ruwart
authors.forename: K S
authors.initials: KS
authors.lastname: Henley
mesh_terms: D000818:Animals; D003362:Cost-Benefit Analysis; D006084:Graft Rejection / Q000503:physiopathology / Q000517:prevention & control; D006801:Humans; D008107:Liver Diseases / Q000188:drug therapy* / Q000601:surgery; D016031:Liver Transplantation; D008833:Microcirculation / Q000187:drug effects; D009926:Organ Preservation; D011453:Prostaglandins / Q000191:economics / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D011453:Prostaglandins