title: [Acute schistosomiasis with brain involvement. Case report].
abstract: A case of acute schistosomiasis with magnetic resonance images (MRI) of the brain suggestive of demyelinating lesions, pyramidal disorder in the lower limbs and normal cerebrospinal fluid is presented. Diagnosis could be established by detection of antibodies on blood and cerebrospinal fluid. Schistosoma mansoni involves the spinal cord more often than the brain. Praziquantel associated to prednisolone was effective in this case. There are few reports of brain involvement with S. mansoni, but its prevalence is probably greater. Due to the paucity of studies, its pathophysiology and therapeutics remain to be better clarified. The immune and MRI aspects are emphasized.
authors.affiliation: Departamento de Clínica Médica, Hospital de Clínicas da Universidade, Federal do Paraná (UFPR), Curitiba, Brasil.
authors.forename: C D
authors.initials: CD
authors.lastname: Urban
authors.forename: E J
authors.initials: EJ
authors.lastname: Piovesan
authors.forename: S M
authors.initials: SM
authors.lastname: De Almeida
authors.forename: P A
authors.initials: PA
authors.lastname: Kowacs
authors.forename: G
authors.initials: G
authors.lastname: Minguetti
authors.forename: L C
authors.initials: LC
authors.lastname: Werneck
mesh_terms: D000208:Acute Disease; D000328:Adult; D001927:Brain Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D012555:Schistosomiasis mansoni / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000188:drug therapy