title: [The clinical aspects of the pathomorphosis of tuberculosis of the respiratory organs in adults (based on data from autopsy material)].
abstract: With the purpose of studying the clinical aspects of pathomorphosis of tuberculosis of the respiratory organs of different genesis in adults, a comparison was done between the clinical data and results of postmortem examinations of necropsies of 1814 those declased who had died of primary (n = 250) and secondary (n = 1564) tuberculosis over 45 years (1947-1992). Important changes were found out to occur in the clinical course of primary and secondary tuberculosis of the respiratory organs in adults secondary to induced pathomorphosis. Deaths of primary forms of tuberculosis had reduced from 20.3% to 5.4%, while those of secondary tuberculosis increased from 79.7% to 94.6%. In tuberculosis of primary genesis, major proportion of the patients died as a result of the development of generalized forms of the specific process and marked tubintoxication, in secondary tuberculosis they died from formation of chronic cor pulmonale and cardiopulmonary insufficiency. At present, reversion is identified of grave forms of primary and secondary tuberculosis which were common in the past.
authors.forename: M I
authors.initials: MI
authors.lastname: Sakhelashvili
mesh_terms: D000208:Acute Disease; D000328:Adult; D001344:Autopsy / Q000706:statistics & numerical data; D002908:Chronic Disease; D006801:Humans; D008875:Middle Aged; D014388:Tuberculosis, Lymph Node / Q000401:mortality / Q000473:pathology; D014391:Tuberculosis, Miliary / Q000401:mortality / Q000473:pathology; D014397:Tuberculosis, Pulmonary / Q000401:mortality / Q000473:pathology*; D014455:Ukraine / Q000453:epidemiology