title: Assessment of exposure to polycyclic aromatic hydrocarbons during firefighting by measurement of urinary 1-hydroxypyrene.
abstract: Firefighters may be exposed to carcinogenic agents in the smoke from fires, and there has been some concern regarding firefighters' risk of developing occupational-related cancer. Polycyclic aromatic hydrocarbons (PAHs) are present in most fires, posing a cancer risk. The objective of this study was to evaluate the PAH exposure among firefighters. Students (n = 9) and teachers (n = 4) at a firefighter training school delivered urine samples before and 6 to 7 hours after extinguishing burning diesel fuel. The urine samples were analyzed by high-performance liquid chromatography for 1-hydroxypyrene. A small but significant increase in 1-hydroxypyrene levels in the urine was found after the firefighting. This means that firefighting may cause exposure to PAHs. Although the exposure levels were low in this study, they may be different during other types of fires.
authors.affiliation: Division for Occupational Medicine, University of Bergen, Norway.
authors.forename: B E
authors.initials: BE
authors.lastname: Moen
authors.forename: S
authors.initials: S
authors.lastname: Ovrebø
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004784:Environmental Monitoring / Q000379:methods*; D005390:Fires; D006801:Humans; D008875:Middle Aged; D009153:Mutagens / Q000032:analysis*; D016273:Occupational Exposure / Q000032:analysis*; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis*; D011721:Pyrenes / Q000032:analysis*; D012906:Smoke / Q000009:adverse effects*; D014556:Urine / Q000737:chemistry
chemical_list: D009153:Mutagens; D011084:Polycyclic Aromatic Hydrocarbons; D011721:Pyrenes; D012906:Smoke; C033146:1-hydroxypyrene