title: [Static contrast sensitivity in idiopathic Parkinson disease].
abstract: During Parkinson's disease static contrast sensitivity (C.S.) abnormalities are linked to an impairment of the sensitive visual function. C.S. was tested in twelve parkinsonians and 12 controls without neurological and/or ophthalmological pathology, using a Colored Stripes Electronic Generator (GEPCO). Results for parkinsons showed a general deficiency over the spectrum of spatial frequencies, which was statistically significant and particularly pronounced for intermediate frequencies. This study was repeated for three patients: it showed threshold deterioration for two of them, correlated by evolution in the disease, and an improvement for the third patient after introduction of dopatherapy. C.S. is subjected to dopaminergic control. Among parkinsonians. C.S. deterioration may result in an operating failure of both the visual cortex and retina, and is improved by dopatherapy. The Static Gepco contrast sensitivity test is easy to reproduce and can be used easily to monitor the sensory visual defect in parkinsonian patients under treatment.
authors.affiliation: Service de Biophysique, Hôpital Lariboisière, Paris.
authors.forename: I
authors.initials: I
authors.lastname: Ingster-Moati
authors.forename: P
authors.initials: P
authors.lastname: Le Coz
authors.forename: E
authors.initials: E
authors.lastname: Albuisson
authors.forename: G
authors.initials: G
authors.lastname: Fromont
authors.forename: C
authors.initials: C
authors.lastname: Pierron
authors.forename: Y
authors.initials: Y
authors.lastname: Grall
authors.forename: M
authors.initials: M
authors.lastname: Haguenau
mesh_terms: D000368:Aged; D015350:Contrast Sensitivity; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000503:physiopathology*; D012680:Sensitivity and Specificity; D014787:Vision Tests