Retinal development: communication helps you see the light.
Recent studies suggest that interactions between neurons, glial cells and endothelial cells are critical in determining the structure of the retina and the optic nerve. Dysregulation of these interactions can lead to disruption of retinal architecture and impairment of vision.
Wechsler-Reya
R J
RJ
Department of Developmental Biology, Stanford University School of Medicine, Stanford, California 94305, USA.
Barres
B A
BA
D000818:Animals; D001253:Astrocytes / Q000166:cytology / Q000378:metabolism*; D001369:Axons / Q000502:physiology; D001808:Blood Vessels / Q000254:growth & development; D016228:Endothelial Growth Factors / Q000378:metabolism*; D004847:Epithelial Cells; D005724:Ganglia / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D008222:Lymphokines / Q000378:metabolism*; D008954:Models, Biological; D009457:Neuroglia / Q000166:cytology / Q000378:metabolism; D009474:Neurons / Q000166:cytology / Q000378:metabolism*; D009900:Optic Nerve / Q000166:cytology; D010100:Oxygen; D010982:Platelet-Derived Growth Factor / Q000378:metabolism*; D017479:Receptors, Platelet-Derived Growth Factor / Q000378:metabolism; D012160:Retina / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism*; D012178:Retinopathy of Prematurity / Q000209:etiology / Q000517:prevention & control; D015398:Signal Transduction; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors; D014785:Vision, Ocular
D016228:Endothelial Growth Factors; D008222:Lymphokines; D010982:Platelet-Derived Growth Factor; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors; D017479:Receptors, Platelet-Derived Growth Factor; D010100:Oxygen