title: A new tick-borne encephalitis-like virus infecting New England deer ticks, Ixodes dammini.
abstract: To determine if eastern North American Ixodes dammini, like related ticks in Eurasia, maintain tick-borne encephalitis group viruses, we analyzed ticks collected from sites where the agent of Lyme disease is zoonotic. Two viral isolates were obtained by inoculating mice with homogenates from tick salivary glands. The virus, which was described by reverse transcriptase polymerase chain reaction and direct sequencing of the amplification products, was similar to, but distinct from, Powassan virus and is provisionally named "deer tick virus." Enzootic tick-borne encephalitis group viruses accompany the agents of Lyme disease, babesiosis, and granulocytic ehrlichiosis in a Holarctic assemblage of emergent deer tick pathogens.
authors.affiliation: Harvard School of Public Health, Boston, Massachusetts, USA.
authors.forename: S R
authors.initials: SR
authors.lastname: Telford
authors.forename: P M
authors.initials: PM
authors.lastname: Armstrong
authors.forename: P
authors.initials: P
authors.lastname: Katavolos
authors.forename: I
authors.initials: I
authors.lastname: Foppa
authors.forename: A S
authors.initials: AS
authors.lastname: Garcia
authors.forename: M L
authors.initials: ML
authors.lastname: Wilson
authors.forename: A
authors.initials: A
authors.lastname: Spielman
mesh_terms: D000818:Animals; D004668:Encephalitis Viruses / Q000145:classification / Q000302:isolation & purification* / Q000472:pathogenicity; D018884:Ixodes / Q000821:virology*; D051379:Mice; D016133:Polymerase Chain Reaction