Assembly process of 2D protein arrays in wetting films.
We were successful in developing a technique to form protein array developed directly on solid surfaces. This promising array formation revealed two new concepts of the ordering mechanism: the lifetime of a secondary minimum and secondary films. These concepts are not limited to our film formation technique. Any electrolytic thin film on a solid surfaces or any free film may contain a secondary film. If the secondary film can be retained in an electrolytic thin film for a sufficient period, a large single domain of small colloidal particles, such as proteins, fine metal particles, fine semi-conductive particles, etc., can be produced by an Alder-type transition.
Adachi
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E
Nagayama Protein Array Project, ERATO, JRDC, Tsukuba, Japan.
Nagayama
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K
D000388:Air; D001709:Biotechnology / Q000379:methods; D011485:Protein Binding; D011506:Proteins / Q000737:chemistry*; D012825:Silicon; D012996:Solutions; D013499:Surface Properties
D011506:Proteins; D012996:Solutions; D012825:Silicon