[A case of severe odontogenic infection with allergic skin reaction for beta-lactam antibiotics].
A 54-aged woman consulted with right buccal phlegmon caused by lower apical periodontitis. The primary chemotherapy using flomoxef induced allergic skin eruption. A decision was made for using clindamycin, levofloxacin and fosfomycin as chemotherapeutic agents. Cultured organisms from the abscess revealed the mixed infection with Streptococcus sanguis, Veillonella sp., Prevotella loescheii, Wolinella spp. On 12th hospital day, her serum CRP turned to negative. This case carried numerous implications for the use of antibiotics as chemotherapy agents.
Kuriyama
T
T
Department of Oral and Maxillofacial Surgery, School of Medicine, Kanazawa University.
Nakagawa
K
K
Saiki
Y
Y
Yamamoto
E
E
D000328:Adult; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D002481:Cellulitis / Q000188:drug therapy / Q000209:etiology; D002511:Cephalosporins / Q000009:adverse effects*; D002981:Clindamycin / Q000008:administration & dosage; D003875:Drug Eruptions / Q000209:etiology*; D004359:Drug Therapy, Combination / Q000008:administration & dosage; D005260:Female; D005578:Fosfomycin / Q000008:administration & dosage; D006801:Humans; D064704:Levofloxacin; D015242:Ofloxacin / Q000008:administration & dosage; D010482:Periapical Abscess / Q000188:drug therapy* / Q000382:microbiology
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D005578:Fosfomycin; D002981:Clindamycin; D064704:Levofloxacin; D015242:Ofloxacin; C045693:flomoxef