Cytopathologic features of hepatic epithelioid hemangioendothelioma.
We present the cytological features of hepatic epithelioid hemangioendothelioma (EH), which is considered to be a vascular proliferation of intermediate malignant potential. The case report concerns a 52-yr-old previously healthy man discovered to have multiple hepatic masses upon evaluation for abnormal liver function tests. Fine-needle aspiration demonstrated a neoplasm composed of interanastomosing epithelioid cells that contained intracytoplasmic lumens. Histologic sections, immunohistochemistry, and ultrastructural evaluation were confirmatory. Although hepatic EH is a rare tumor, its characteristic cytological, histological, and ultrastructural features permit a straightforward diagnosis. It is important to distinguish this entity from adenocarcinoma and angiosarcoma because long-term disease-free survival is possible, especially in the setting of orthotopic liver transplantation.
Soslow
R A
RA
Department of Pathology, New York Hospital-Cornell Medical Center, New York 10021, USA.
Yin
P
P
Steinberg
C R
CR
Yang
G C
GC
D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D018323:Hemangioendothelioma, Epithelioid / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008875:Middle Aged