[Treatment of arterial hypertension with renal involvement].
TREATMENT GUIDELINES: To prevent the development of hypertensive renal disease of progression of underlying renal disease, the blood pressure goal should be 130/85 mmHg or less if possible when proteinuria exceeds 1 g/24 h. ANTIHYPERTENSIVE DRUGS: Converting enzyme inhibitors are recommended in patients with non-diabetic renal disease and, as first-line therapy, in diabetics with microalbuminurea or patent diabetic nephropathy with or without hypertension. TREATMENT ONSET: Converting enzyme inhibitors should be started progressively with a lower final dosage in case of renal failure. Creatinemia and kaliemia must be monitored. Combination therapy with diuretics is generally used, but potassium-sparing diuretics are contraindicated due to the risk of hyperkaliemia. Reduced sodium intake is essential to obtain maximum effect.
Bobrie
G
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Service de Néphrologie et d'Hypertension artérielle, Centre Hospitalier, Vannes.
D000959:Antihypertensive Agents / Q000627:therapeutic use; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy / Q000628:therapy*; D007674:Kidney Diseases / Q000188:drug therapy / Q000209:etiology / Q000628:therapy*
D000959:Antihypertensive Agents