title: [Orthotopic bladder replacement: I. Physiopathology of orthotopic bladder replacement with intestine].
abstract: OBJECTIVE
  To analyze the physiopathological principles of utilizing the bowel for orthotopic bladder substitution and their effects on metabolism, function and continence.
  
  
  METHODS
  The world literature is reviewed and our experience of 100 cases is described in the third part of this study.
  
  
  CONCLUSIONS
  To reduce the metabolic changes, utilization of colonic or ileal segments with a maximum length of about 40 cm is advocated. This length of detubulized intestinal segment permits creating an ample, low pressure reservoir with an antireflux mechanism. The precise incidence of neoplastic degeneration of the ileal and colonic reservoirs is not known, but appears to be lower for the ileal neobladder.
authors.affiliation: Servicio de Urología, Fundación Puigvert, Barcelona, España.
authors.forename: C
authors.initials: C
authors.lastname: Errando Smet
authors.forename: R
authors.initials: R
authors.lastname: Regalado Pareja
authors.forename: J
authors.initials: J
authors.lastname: Huguet Pérez
authors.forename: B
authors.initials: B
authors.lastname: Xavier Lima
authors.forename: G
authors.initials: G
authors.lastname: Chéchile Toniolo
authors.forename: H
authors.initials: H
authors.lastname: Villavicencio Mavrich
mesh_terms: D006801:Humans; D007413:Intestinal Mucosa / Q000378:metabolism; D007422:Intestines / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D016476:Urinary Reservoirs, Continent / Q000379:methods*