title: Non-invasive blood glucose monitoring by means of near infrared spectroscopy: methods for improving the reliability of the calibration models.
abstract: The feasibility of using near infrared reflection spectroscopy for non-invasive blood glucose monitoring is discussed. Spectra were obtained using a diode-array spectrometer with a fiberoptic measuring head with a wavelength ranging from 800 nm to 1350 nm. Calibration was performed using partial least-squares regression and radial basis function networks. The results of different methods used to evaluate the quality of the recorded spectra in order to improve the reliability of the calibration models, are presented.
authors.affiliation: Department for Internal Medicine II, Medical School, Friedrich Schiller University, Jena, Germany.
authors.forename: U A
authors.initials: UA
authors.lastname: Müller
authors.forename: B
authors.initials: B
authors.lastname: Mertes
authors.forename: C
authors.initials: C
authors.lastname: Fischbacher
authors.forename: K U
authors.initials: KU
authors.lastname: Jageman
authors.forename: K
authors.initials: K
authors.lastname: Danzer
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D015190:Blood Glucose Self-Monitoring / Q000295:instrumentation / Q000379:methods; D002138:Calibration; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D019265:Spectroscopy, Near-Infrared
chemical_list: D001786:Blood Glucose