title: Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1 beta-converting enzyme inhibitor.
authors.affiliation: Sanofi Winthrop Inc., Collegeville, Pennsylvania 19426, USA.
authors.forename: R E
authors.initials: RE
authors.lastname: Dolle
authors.forename: C V
authors.initials: CV
authors.lastname: Prasad
authors.forename: C P
authors.initials: CP
authors.lastname: Prouty
authors.forename: J M
authors.initials: JM
authors.lastname: Salvino
authors.forename: M M
authors.initials: MM
authors.lastname: Awad
authors.forename: S J
authors.initials: SJ
authors.lastname: Schmidt
authors.forename: D
authors.initials: D
authors.lastname: Hoyer
authors.forename: T M
authors.initials: TM
authors.lastname: Ross
authors.forename: T L
authors.initials: TL
authors.lastname: Graybill
authors.forename: G J
authors.initials: GJ
authors.lastname: Speier
authors.forename: J
authors.initials: J
authors.lastname: Uhl
authors.forename: B E
authors.initials: BE
authors.lastname: Miller
authors.forename: C T
authors.initials: CT
authors.lastname: Helaszek
authors.forename: M A
authors.initials: MA
authors.lastname: Ator
mesh_terms: D000818:Animals; D001381:Azepines / Q000737:chemistry* / Q000493:pharmacokinetics; D004285:Dogs; D015195:Drug Design; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000493:pharmacokinetics; D008657:Metabolic Clearance Rate; D011724:Pyridazines / Q000737:chemistry* / Q000493:pharmacokinetics; D015843:Serpins / Q000138:chemical synthesis* / Q000493:pharmacokinetics; D014764:Viral Proteins
chemical_list: D001381:Azepines; D004791:Enzyme Inhibitors; D011724:Pyridazines; D015843:Serpins; D014764:Viral Proteins; C074641:interleukin-1beta-converting enzyme inhibitor