[Pharmacotherapy of depressed patients. Increasing the therapeutic arsenal with a new generation of antidepressive drugs].
Antidepressants form the core of the biological approach to antidepressive treatment. The present paper presents and discusses the basic principles of treatment with antipressants, for example selection criteria, dosage, maintenance therapy, etc. In particular new developments in the area of pharmacotherapeutic treatment are examined. In comparison with the classical tricyclic antidepressants, antidepressants of the third generation such as SSRI, selective and reversible MAO-A inhibitors, antidepressants with a dual mode of action acting selectively on specific neurotransmitter systems, seem to be better tolerated while offering comparable efficacy.
Möller
H J
HJ
Psychiatrische Klinik und Poliklinik, Universität München.
D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003866:Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D006801:Humans; D008134:Long-Term Care; D013405:Suicide / Q000523:psychology; D000092864:Suicide Prevention
D000928:Antidepressive Agents