title: A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes.
abstract: A very short hydrogen bond between an Asp and a phosphate is established in two high resolution structures (0.98 and 1.05 A). A mutant complex that changes the Asp to an Asn, which forms a normal hydrogen bond, has a similar free energy of binding to the wild type complex, suggesting that the contribution of the short hydrogen bond is not extraordinarily strong.
authors.forename: Z
authors.initials: Z
authors.lastname: Wang
authors.forename: H
authors.initials: H
authors.lastname: Luecke
authors.forename: N
authors.initials: N
authors.lastname: Yao
authors.forename: F A
authors.initials: FA
authors.lastname: Quiocho
mesh_terms: D002352:Carrier Proteins / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism*; D018360:Crystallography, X-Ray; D006860:Hydrogen Bonding; D006863:Hydrogen-Ion Concentration; D008958:Models, Molecular; D009154:Mutation; D028044:Phosphate-Binding Proteins; D010710:Phosphates / Q000737:chemistry* / Q000378:metabolism*; D011487:Protein Conformation
chemical_list: D002352:Carrier Proteins; D028044:Phosphate-Binding Proteins; D010710:Phosphates