Thrombocytopenic purpura and anemia in a breast-fed infant whose mother was treated with valproic acid.
Valproic acid is an antiepileptic drug in widespread use. The possibility of various hematologic side effects with this drug is well recognized. We describe a breast-fed infant with thrombocytopenic purpura, anemia, and reticulocytosis, whose mother was treated with valproic acid. As the mother stopped breast-feeding, the infant recovered.
Stahl
M M
MM
Pharmacoepidemiology Unit, Medical Products Agency, Uppsala, Sweden.
Neiderud
J
J
Vinge
E
E
D000740:Anemia / Q000209:etiology*; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D001942:Breast Feeding; D004827:Epilepsy / Q000188:drug therapy; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008429:Maternal Welfare; D011696:Purpura, Thrombocytopenic / Q000209:etiology*; D014635:Valproic Acid / Q000009:adverse effects* / Q000627:therapeutic use
D000927:Anticonvulsants; D014635:Valproic Acid