In vitro trypanocidal activity of some rare Tanzanian medicinal plants.
Extracts prepared from 15 rare Tanzanian medicinal plants were tested for their in vitro antitrypanosomal activity against human pathogenic trypanosomes (Trypanosoma brucei rhodesiense). Of 37 extracts investigated, two were found to have strong activity with IC50 values below 1 microgram/ml and ten extracts revealed promising activities with IC50 values between 1-5 micrograms/ml.
Freiburghaus
F
F
Swiss Tropical Institute, Basel, Switzerland.
Jonker
S A
SA
Nkunya
M H
MH
Mwasumbi
L B
LB
Brun
R
R
D000818:Animals; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal; D013636:Tanzania; D016833:Trypanosoma brucei rhodesiense / Q000187:drug effects*
D010936:Plant Extracts