title: Preoperative chemotherapy for congenital hemangiopericytoma and a review of the literature.
abstract: OBJECTIVE
  Malignant hemangiopericytoma is an uncommon tumor in the pediatric age group. A case of congenital hemangiopericytoma is presented with a review of the literature.
  
  
  METHODS
  A 2-month-old boy presented at birth with an enlarging posterior neck mass. Subsequent histopathologic studies showed findings consistent with hemangiopericytoma. Imaging studies demonstrated an extensive, infiltrative, vascular lesion not readily amenable to surgical resection. A pulmonary metastatic lesion was present.
  
  
  RESULTS
  Combined treatment using vincristine, doxorubicin, and cyclophosphamide given preoperatively resulted in a significant decrease in size of the primary tumor, allowing for resection without complication and resolution of the metastatic lesion.
  
  
  CONCLUSIONS
  Preoperative chemotherapy may have a significant role in the management of infants with malignant hemangiopericytoma.
authors.affiliation: Division of Pediatric Hematology/Oncology, University of Florida Health Science Center, Gainesville, USA.
authors.forename: M L
authors.initials: ML
authors.lastname: del Rosario
authors.forename: A
authors.initials: A
authors.lastname: Saleh
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006258:Head and Neck Neoplasms / Q000151:congenital* / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery; D006393:Hemangiopericytoma / Q000151:congenital* / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D007223:Infant; D008175:Lung Neoplasms / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008297:Male; D011300:Preoperative Care; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide