title: Cytoarchitecture of the entorhinal cortex in schizophrenia.
abstract: OBJECTIVE
  The purpose of this study was to determine whether schizophrenia is associated with abnormalities in neuronal migration in the entorhinal cortex.
  
  
  METHODS
  Nissl-stained sections through three cytoarchitectonic subdivisions of the entorhinal cortex were examined in postmortem brain specimens from 10 schizophrenic subjects and 10 matched normal comparison subjects.
  
  
  RESULTS
  No qualitative differences in cytoarchitecture were observed between the schizophrenic and comparison subjects.
  
  
  CONCLUSIONS
  These findings do not replicate previous reports of cytoarchitectural disturbances in the entorhinal cortex of schizophrenic subjects and thus fail to support the hypothesis of abnormal neuronal migration in schizophrenia.
authors.affiliation: Department of Psychiatry, University of Pittsburgh, PA 15213, USA.
authors.forename: M
authors.initials: M
authors.lastname: Akil
authors.forename: D A
authors.initials: DA
authors.lastname: Lewis
mesh_terms: D018728:Entorhinal Cortex / Q000002:abnormalities / Q000033:anatomy & histology*; D006801:Humans; D009436:Neural Tube Defects / Q000473:pathology; D012559:Schizophrenia / Q000175:diagnosis* / Q000473:pathology