Subclinical rubella reinfection during pregnancy followed by transmission of virus to the fetus.
We report a documented case of rubella reinfection during pregnancy in a previously vaccinated woman with residual antibody titre to rubella of 15 IU/ml. The reinfection occurred following an exposure to rubella virus (contact with 6-year-old daughter with clinical rubella) between the 7th and 10th week of pregnancy which resulted in transmission of the virus to the fetus. Umbilical cord blood drawn by cordocentesis was found to be strongly positive for rubella IgM antibody. After termination of the pregnancy rubella virus was isolated in cell culture from fetal tissues.
Aboudy
Y
Y
Central Virology Laboratory, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Fogel
A
A
Barnea
B
B
Mendelson
E
E
Yosef
L
L
Frank
T
T
Shalev
E
E
D000328:Adult; D005260:Female; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000821:virology*; D012008:Recurrence; D012409:Rubella / Q000635:transmission*