Anatomical and neurological correlates of acute and chronic visuospatial neglect following right hemisphere stroke.
Anatomical and neurological correlates of visuospatial neglect were studied in 53 patients with a CT-documented right hemisphere stroke. Evidence of neglect at the acute stage poststroke was strongly related to large lesions involving the middle temporal gyrus and/or the temporo-parietal paraventricular white matter. Thus, out of 18 patients with evidence of visuospatial neglect at the acute stage, 12 showed a lesion in the middle temporal gyrus and/or the deep temporo-parietal white matter. Among the 35 patients that failed to show visuospatial neglect, only one patient had a lesion within these areas. Comparing those patients who recovered from neglect with those that did not, a high correlation was found between persisting neglect and a lesion involving the paraventricular white matter in the temporal lobe. On the basis of above findings, it was suggested that a simultaneous damage to the cortico-thalamic system for regulation of arousal and to the neural systems mediating visual orienting, is likely to be followed by persisting neglect symptoms.
Samuelsson
H
H
Dept. of Psychology, University of Göteborg, Sweden.
Jensen
C
C
Ekholm
S
S
Naver
H
H
Blomstrand
C
C
D000328:Adult; D001143:Arousal / Q000502:physiology; D001288:Attention / Q000502:physiology*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000503:physiopathology*; D002552:Cerebral Ventricles / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D004292:Dominance, Cerebral / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006423:Hemianopsia / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D006429:Hemiplegia / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D009949:Orientation / Q000502:physiology*; D010296:Parietal Lobe / Q000503:physiopathology; D013702:Temporal Lobe / Q000503:physiopathology; D014057:Tomography, X-Ray Computed; D014794:Visual Fields / Q000502:physiology