[An epidemiologic study on the aetiological factors of primary liver cancer in Shunde City of Guangdong province].
In order to investigate the aetiological factors of Primary Liver Cancer (PLC) in Shunde City of Guangdong province, 96 clinically diagnosed PLC patients and 144 matched hospital controls were interviewed and their blood samples were examined for HBV, HCV and other seven indices. Monofactorial and multifactorial analyses were fitted by using Non-conditional Logistic Regression model. The findings confirmed the strong association between HBV infection and PLC. Histories of hepatitis and histories of eating raw fish, shrimp or salt fish were also noticed. The history of alcohol intake might have associated with PLC. The present study did not find associations between PLC and drinking water, histories of blood transfusion and injection- or exposure to insecticides. Antibody of HBV surface antigen seemed to be a protective factor with a relative risk of 0.3064 (0.1647-0.5701). The results showed that the combined effects of HBsAg infection and HCV infection were worthy for further study.
Wang
Z J
ZJ
Department of Epidemiology, Sun Yat-sen University of Med. Sc.
Zhou
Y P
YP
Cheng
B
B
D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D006509:Hepatitis B / Q000150:complications; D006514:Hepatitis B Surface Antigens / Q000097:blood; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D008113:Liver Neoplasms / Q000453:epidemiology* / Q000209:etiology / Q000276:immunology; D016015:Logistic Models; D012307:Risk Factors
D006514:Hepatitis B Surface Antigens; D018937:Hepatitis C Antibodies