title: The views of members of Local Research Ethics Committees, researchers and members of the public towards the roles and functions of LRECs.
abstract: BACKGROUND
  It can be argued that the ethical conduct of research involves achieving a balance between the rights and needs of three parties-potential research participants, society, and researchers. Local Research Ethics Committees (LRECs) have a number of roles and functions in the research enterprise, but there have been some indications that LREC members, researchers and the public can have different views about these responsibilities. Any such differences are potential sources of disagreement and misunderstanding.
  
  
  OBJECTIVE
  To compare the views of LREC members, researchers and the public towards the roles and functions of LRECs.
  
  
  METHODS
  A questionnaire that contained items concerned with a variety of such roles was distributed to general practice patients (as proxies for potential research participants), researchers and LREC members.
  
  
  RESULTS
  While general practice patients believed that the main function of LRECs is to ensure that research participants come to no harm, LREC members were more concerned with the protection of participants' rights. There was also some disagreement between members and researchers with regard to the consideration of proposals on the grounds of scientific merit.
  
  
  CONCLUSIONS
  Local Research Ethics Committee members need to be aware of potential differences in views, that they ought to make their priorities clear, and that membership of LRECs ought to reflect the views of both researchers and potential research participants.
authors.affiliation: Northern General Hospital, Sheffield.
authors.forename: G
authors.initials: G
authors.lastname: Kent
mesh_terms: D001291:Attitude of Health Personnel; D026686:Beneficence; D032802:Committee Membership; D030881:Disclosure; D004739:England; D026724:Ethical Review; D017041:Ethics Committees; D028744:Ethics Committees, Research; D005194:Family Practice; D006801:Humans; D007258:Informed Consent / Q000331:legislation & jurisprudence*; D026684:Personal Autonomy; D011639:Public Opinion; D035842:Research Subjects; D018570:Risk Assessment; D011795:Surveys and Questionnaires