title: [Glucagonoma: case report and literature review].
abstract: Glucagonoma is a neuroendocrine tumor of pancreatic alpha cells manifested by necrolytic migratory erythema, hyperglucagonemia, glucose intolerance, weight loss, anemia and hypopaminoacidemia. We report a case of glucagonoma in a 38 years-old patient diagnosed by the presence of a pancreatic tumor, liver metastasis, weight loss, glucose intolerance, necrolytic migratory erythema, hyperglucagonemia (1400 pg/ml; normal < 200 pg/ml) and histologic demonstration of glucagon and neurospecific enolase by immunocytochemical reaction. Actual therapeutic of glucagonoma includes surgery, chemotherapy, somatostatin or octreotide for control of the symptoms, and more recently alpha-interferon was suggested.
authors.affiliation: UNIFESP-EPM.
authors.forename: M M
authors.initials: MM
authors.lastname: das Neves
authors.forename: E V
authors.initials: EV
authors.lastname: Martins Júnior
authors.forename: A K
authors.initials: AK
authors.lastname: Gaburri
authors.forename: J M
authors.initials: JM
authors.lastname: Chebli
authors.forename: J N
authors.initials: JN
authors.lastname: Stávale
authors.forename: A K
authors.initials: AK
authors.lastname: Herani Filho
mesh_terms: D000328:Adult; D005935:Glucagonoma / Q000473:pathology* / Q000556:secondary; D006801:Humans; D008297:Male; D010190:Pancreatic Neoplasms / Q000473:pathology*