title: Eosinophil cationic protein in tracheal aspirates of preterm infants with bronchopulmonary dysplasia.
abstract: Eosinophil cationic protein was elevated during the first week of life in tracheal aspirates from 11 preterm infants in whom bronchopulmonary dysplasia subsequently developed compared with 8 preterm and 8 term infants without bronchopulmonary dysplasia. Eosinophil cationic protein levels increased progressively with continued intubation in the infants with bronchopulmonary dysplasia but remained low in a comparison group of term infants. We suggest that eosinophils participate in the inflammatory process in bronchopulmonary dysplasia and may contribute to lung injury.
authors.affiliation: Division of Neonatology, University of California at Los Angeles Children's Hospital 90095-1752, USA.
authors.forename: B
authors.initials: B
authors.lastname: Raghavender
authors.forename: J B
authors.initials: JB
authors.lastname: Smith
mesh_terms: D001997:Bronchopulmonary Dysplasia / Q000150:complications / Q000175:diagnosis*; D002412:Cations; D004804:Eosinophils; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D011506:Proteins / Q000032:analysis*; D011863:Radioimmunoassay; D012121:Respiration, Artificial; D012127:Respiratory Distress Syndrome, Newborn / Q000209:etiology / Q000534:rehabilitation; D014132:Trachea
chemical_list: D002412:Cations; D011506:Proteins