title: Successful diagnosis and management of cytomegalovirus carditis.
abstract: Cytomegalovirus (CMV)-associated carditis in the immunosuppressed patient carries a 60% mortality. Underlying pathogenesis is poorly understood but may involve either direct viral invasion or autoimmune cardiac damage triggered in response to the infection. Specific anti-cytomegalovirus therapy and/or anti-inflammatory drugs have been shown to benefit in cases where an early diagnosis was established. We report an unusual case of endo-pericarditis which was temporally related to acute cytomegalovirus infection diagnosed by the immediate early antigen detection in cell culture on whole blood.
authors.affiliation: Regional Department of Infectious Diseases and Tropical Medicine, North Manchester General Hospital, U.K.
authors.forename: T T
authors.initials: TT
authors.lastname: Ng
authors.forename: D J
authors.initials: DJ
authors.lastname: Morris
authors.forename: E G
authors.initials: EG
authors.lastname: Wilkins
mesh_terms: D000328:Adult; D003586:Cytomegalovirus Infections / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D006801:Humans; D009205:Myocarditis / Q000175:diagnosis* / Q000628:therapy