Recent advances in managing non-small-cell lung cancer: 2. Surgery.
Surgery can be curative in non-small-cell lung cancer, but has only a minor role in small-cell lung cancer. About two-thirds of patients with non-small-cell lung cancer present with advanced disease that cannot be treated surgically. Lymph node involvement alone does not indicate inoperable or incurable cancer. Lobectomy in patients with Stage I disease results in a five-year survival rate of 70%. Lobectomy or pneumonectomy with resection of involved nodes in patients with Stage II disease has a five-year survival rate of 40%-45%. Carefully selected patients with Stage IIIA disease may benefit from surgical treatment.
McCaughan
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Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, NSW.
D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D009367:Neoplasm Staging; D018579:Patient Selection; D011013:Pneumonectomy