Health-related quality of life after ileoanal pull-through evaluation and assessment of new health status measures.
OBJECTIVE
Health-related quality of life (HRQL) after proctocolectomy is a critical parameter for management decisions in patients with chronic pancolitis. The aim of this study was to evaluate the HRQL of patients with ileoanal pull-through and to validate new, easy-to-administer HRQL measures.


METHODS
The Sickness Impact Profile (SIP), Short Form 36 (SF-36), Rating Form of Inflammatory Bowel Disease (IBD) Patient Concerns (RFIPC), and the time trade-off (TTO) were used to measure HRQL of pull-through patients. The SF-36 and the RFIPC were validated.


RESULTS
HRQL of patients with ileoanal pull-through was better than that of a national sample of patients with IBD (SIP and RFIPC) and similar to that of a normal population (SF-36). Physical and psychosocial subscales of the SF-36 correlated with the SIP, affirming the construct validity of the SF-36. The RFIPC results correlated with the SIP and SF-36 results, suggesting that it is also a valid health status measure for these patients. TTO results correlated with the physical subscales of the SIP and SF-36, reflecting the impact of physical health on this group.


CONCLUSIONS
HRQL of patients with ileoanal pull-through is excellent. The SF-36 and RFIPC are valid health status measures that can be used by clinicians and researchers in these patients.
Provenzale
D
D
Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.
Shearin
M
M
Phillips-Bute
B G
BG
Drossman
D A
DA
Li
Z
Z
Tillinger
W
W
Schmitt
C M
CM
Bollinger
R R
RR
Koruda
M J
MJ
D000328:Adult; D003093:Colitis, Ulcerative / Q000523:psychology / Q000601:surgery*; D005069:Evaluation Studies as Topic; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D016737:Proctocolectomy, Restorative / Q000523:psychology*; D011788:Quality of Life; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires