title: Bacteraemia during direct laryngoscopy and endotracheal intubation: a study using a multiple culture, large volume technique.
abstract: Bacteraemia secondary to orotracheal intubation has been reported to occur in 0-5.3% of patients. Bacteraemia detection is dependent upon several factors including the volume of blood per culture and the number of cultures. Prior studies used small volumes of blood and one or two cultures, and may therefore have underestimated the incidence of bacteraemia. Sixty-two adult patients who underwent direct laryngoscopy and endotracheal intubation were studied. Baseline blood cultures were sterile in all patients. After intubation, four blood cultures were obtained in ten minutes, with 10 ml being evenly divided between aerobic and anaerobic media. Two patients (3.2%) became bacteraemic. This is a lower incidence than occurs in association with other procedures for which The American Heart Association does not recommend administration of prophylactic antibiotics. Therefore, prophylactic antibiotics are not recommended prior to direct laryngoscopy. However, when a prophylactic antibiotic is administered prior to surgery, it would be best to administer the antibiotic prior to direct laryngoscopy and intubation.
authors.affiliation: Department of Anesthesia, U.M.D.N.J.-Robert Wood Johnson Medical School, New Brunswick, USA.
authors.forename: S
authors.initials: S
authors.lastname: Goldstein
authors.forename: G L
authors.initials: GL
authors.lastname: Wolf
authors.forename: S J
authors.initials: SJ
authors.lastname: Kim
authors.forename: M F
authors.initials: MF
authors.lastname: Sierra
authors.forename: C
authors.initials: C
authors.lastname: Whitmire
authors.forename: E M
authors.initials: EM
authors.lastname: Tolentino
mesh_terms: D000328:Adult; D019072:Antibiotic Prophylaxis; D016470:Bacteremia / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D006801:Humans; D007442:Intubation, Intratracheal / Q000009:adverse effects*; D007828:Laryngoscopy / Q000009:adverse effects*