title: Anserinones A and B: new antifungal and antibacterial benzoquinones from the coprophilous fungus Podospora anserina.
abstract: Two new benzoquinones with antifungal, antibacterial, and cytotoxic activities have been isolated from liquid cultures of the coprophilous fungus Podospora anserina. The structures of anserinones A (1) and B (2) were assigned on the basis of MS and NMR results, and the absolute stereochemistry of 2 was deduced by analysis of 1H-NMR data for its (R)- and (S)-2-phenylbutyryl ester derivatives.
authors.affiliation: Department of Chemistry, University of Iowa, Iowa City 52242, USA.
authors.forename: H
authors.initials: H
authors.lastname: Wang
authors.forename: K B
authors.initials: KB
authors.lastname: Gloer
authors.forename: J B
authors.initials: JB
authors.lastname: Gloer
authors.forename: J A
authors.initials: JA
authors.lastname: Scott
authors.forename: D
authors.initials: D
authors.lastname: Malloch
mesh_terms: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000302:isolation & purification* / Q000494:pharmacology; D000935:Antifungal Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D016227:Benzoquinones / Q000302:isolation & purification* / Q000494:pharmacology; D005658:Fungi / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013098:Xylariales / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D016227:Benzoquinones; C107779:anserinone A; C107780:anserinone B