title: Necrotising fasciitis--an old enemy or a new foe.
abstract: Necrotising fasciitis when described by Meleney was caused predominantly by Streptococcus pyogenes. Since then, there were several reports which confirmed streptococcus as the main organism identified in this disease entity. However, recently there were reports of necrotising fasciitis caused by organisms other than Streptococcus. We analysed 19 cases of necrotising fasciitis seen in the Department of Orthopaedic Surgery over a period of 24 months to see if this disease entity has changed significantly. The patients in our series were between the ages of 19 to 85 years with an average age of 57.2 years. Males were more often affected (16 out of 19). The majority of the patients have some form of underlying disease (16 out of 19 cases). There was a trend towards polymicrobial infection and many were resistant to standard antimicrobial therapy. The mortality rate was 21.1%. Our results are comparable to many earlier series.
authors.affiliation: Department of Orthopaedic Surgery, Tan Tock Seng Hospital, Singapore.
authors.forename: Y H
authors.initials: YH
authors.lastname: Li
authors.forename: C L
authors.initials: CL
authors.lastname: Toh
authors.forename: C
authors.initials: C
authors.lastname: Khoo
authors.forename: Y P
authors.initials: YP
authors.lastname: Low
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019115:Fasciitis, Necrotizing / Q000175:diagnosis / Q000453:epidemiology* / Q000382:microbiology / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012846:Singapore / Q000453:epidemiology