title: Superior sagittal sinus thrombosis treated with combined local thrombolytic and systemic anticoagulation therapy.
abstract: We recently encountered a patient with thrombosis of the superior sagittal sinus of an idiopathic cause. The patient was treated initially with combined local thrombolytic therapy through the burr hole over the superior sagittal sinus and systemic anticoagulant therapy. Continuous ventricular drainage and hyperbaric oxygenation therapy were used to control the increased intracranial pressure. The superior sagittal sinus was successfully recanalized. Whereas the patient suffered a complication with subacute subdural haematoma, he was successfully treated with the combination of these therapies. The rationale and approach are discussed.
authors.affiliation: Department of Neurosurgery, Tokyo Women's Medical College, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Aoki
authors.forename: H
authors.initials: H
authors.lastname: Uchinuno
authors.forename: T
authors.initials: T
authors.lastname: Tanikawa
authors.forename: M
authors.initials: M
authors.lastname: Kagawa
authors.forename: K
authors.initials: K
authors.lastname: Takakura
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D002550:Cerebral Veins / Q000000981:diagnostic imaging / Q000187:drug effects / Q000473:pathology*; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D015912:Thrombolytic Therapy; D014057:Tomography, X-Ray Computed
chemical_list: D000925:Anticoagulants