title: Tsukamurella tyrosinosolvens sp. nov.
abstract: Chemotaxonomic and 16S ribosomal DNA sequence analyses of four bacterial isolates from blood cultures from patients with cardiac pacemaker implants and sputa of patients with chronic lung infections clearly demonstrated that these bacteria belong to the genus Tsukamurella. DNA-DNA hybridization data, as well as the physiological characteristics of the isolates, indicate that they are closely related and belong to a single species that differs from previously described members of the genus Tsukamurella. The name Tsukamurella tyrosinosolvens sp. nov. is proposed for these isolates, and the new species is represented by strain IMMIB D-1397T (= DSM 44234T). Strain IMMIB D-1397T exhibits 53.4, 53.5, and 54.7% DNA-DNA relatedness to Tsukamurella paurometabola DSM 20162T, Tsukamurella inchonensis DSM 44067T, and Tsukamurella pulmonis DSM 44142T, respectively.
authors.affiliation: Institut für Medizinische Mikrobiologie und Immunologie, Universität Bonn, Germany.
authors.forename: A F
authors.initials: AF
authors.lastname: Yassin
authors.forename: F A
authors.initials: FA
authors.lastname: Rainey
authors.forename: J
authors.initials: J
authors.lastname: Burghardt
authors.forename: H
authors.initials: H
authors.lastname: Brzezinka
authors.forename: S
authors.initials: S
authors.lastname: Schmitt
authors.forename: P
authors.initials: P
authors.lastname: Seifert
authors.forename: O
authors.initials: O
authors.lastname: Zimmermann
authors.forename: H
authors.initials: H
authors.lastname: Mauch
authors.forename: D
authors.initials: D
authors.lastname: Gierth
authors.forename: I
authors.initials: I
authors.lastname: Lux
authors.forename: K P
authors.initials: KP
authors.lastname: Schaal
mesh_terms: D000192:Actinomycetales / Q000145:classification* / Q000235:genetics* / Q000648:ultrastructure; D000193:Actinomycetales Infections / Q000382:microbiology*; D001426:Bacterial Proteins / Q000032:analysis; D001769:Blood / Q000382:microbiology; D002855:Chromatography, Thin Layer; D004269:DNA, Bacterial / Q000032:analysis; D004275:DNA, Ribosomal / Q000032:analysis; D006801:Humans; D008055:Lipids / Q000032:analysis; D008855:Microscopy, Electron, Scanning; D008969:Molecular Sequence Data; D010802:Phylogeny
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; D004275:DNA, Ribosomal; D008055:Lipids