title: Effect of fluvastatin on low-density lipoprotein peak particle diameter.
abstract: The effect of fluvastatin on low-density lipoprotein (LDL) particle diameter was investigated in 42 hypercholesterolemic patients. Fluvastatin reduced LDL cholesterol significantly but had no effect on LDL particle diameter; it also had no differential effect on patients classified as LDL pattern A (large LDL), pattern B (small LDL), or I (intermediate LDL).
authors.affiliation: Cholesterol, Genetics, and Heart Disease Institute, San Mateo, California 94402, USA.
authors.forename: H R
authors.initials: HR
authors.lastname: Superko
authors.forename: R M
authors.initials: RM
authors.lastname: Krauss
authors.forename: C
authors.initials: C
authors.lastname: DiRicco
mesh_terms: D000704:Analysis of Variance; D008078:Cholesterol, LDL / Q000097:blood / Q000187:drug effects*; D004311:Double-Blind Method; D005229:Fatty Acids, Monounsaturated / Q000494:pharmacology / Q000627:therapeutic use*; D000077340:Fluvastatin; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D007211:Indoles / Q000494:pharmacology / Q000627:therapeutic use*; D010316:Particle Size; D012016:Reference Values
chemical_list: D008078:Cholesterol, LDL; D005229:Fatty Acids, Monounsaturated; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D007211:Indoles; D000077340:Fluvastatin