title: MRI of active otosclerosis.
abstract: Our aim was to determine whether MRI reliably shows pathology in patients with active otosclerosis (otospongiosis). We studied five patients with clinical and audiometric signs of this disorder and positive findings on high-resolution CT and tympanocochlear scintigraphy. Contrast enhancement of otospongiotic lesions was found in all affected ears, and could be topographically related to demineralised otospongiotic foci on CT. In lesions in the lateral wall of the labyrinth MRI sometimes showed the pathology better than CT, where partial-volume effects could be troublesome.
authors.affiliation: Section of Neuroradiology, Universitätsklinik Freiburg, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Ziyeh
authors.forename: A
authors.initials: A
authors.lastname: Berlis
authors.forename: U H
authors.initials: UH
authors.lastname: Ross
authors.forename: M J
authors.initials: MJ
authors.lastname: Reinhardt
authors.forename: M
authors.initials: M
authors.lastname: Schumacher
mesh_terms: D000293:Adolescent; D000328:Adult; D003051:Cochlea / Q000473:pathology; D004292:Dominance, Cerebral / Q000502:physiology; D004432:Ear, Middle / Q000473:pathology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010040:Otosclerosis / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed