title: Periprosthetic bone density around fully hydroxyapatite coated femoral stem.
abstract: In this study, periprosthetic bone mineral density was measured at scheduled time intervals after surgery by dual energy x-ray absorptiometry in 21 patients to assess the history of bone density redistribution after femoral stem insertion. Measurements of changes in bone density with time were obtained for the regions of the greater trochanter, the lateral cortex, the tip, the medial cortex, and the calcar. In all regions, bone density decreased during the first 3 months after surgery; this was followed by a prolonged period of 18 to 30 months of bone gain, a subsequent period of steady state, and the final resumption of bone aging processes after the third postoperative year. The greatest loss was observed in the calcar region after 6 months (greater than 50%). The characteristic pattern of time related bone density changes obtained in this study may make it possible to compare other pathologic, design, or stiffness related patterns. This could have clinical relevance in the early diagnosis of pathologic processes and as a means of evaluating prosthetic designs.
authors.affiliation: Clinica Ortopedica II dell' Università degli Studi di Milano, Osp. S. Gerardo-Monza, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Trevisan
authors.forename: M
authors.initials: M
authors.lastname: Bigoni
authors.forename: G
authors.initials: G
authors.lastname: Randelli
authors.forename: E C
authors.initials: EC
authors.lastname: Marinoni
authors.forename: G
authors.initials: G
authors.lastname: Peretti
authors.forename: S
authors.initials: S
authors.lastname: Ortolani
mesh_terms: D015502:Absorptiometry, Photon; D000368:Aged; D001672:Biocompatible Materials; D015519:Bone Density; D017886:Durapatite; D005260:Female; D005269:Femur; D006622:Hip Prosthesis; D006801:Humans; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000503:physiopathology; D017698:Postmenopause; D011446:Prospective Studies
chemical_list: D001672:Biocompatible Materials; D017886:Durapatite