Toxic nephropathies.
A variety of medications can adversely affect the kidney. Awareness of these potential nephrotoxic effects is crucial to prevention of serious sequelae. This review discusses renal injury caused by the chemotherapeutic agent ifosfamide, the problem of analgesic nephropathy, and the newly identified complication of trimethoprim-induced hyperkalemia. In addition, recent information about the classic nephrotoxins (cisplatin, amphotericin B, and aminoglycosides) is presented.
Springate
J E
JE
Division of Nephrology, Children's Hospital, Buffalo, NY 14222, USA.
D000700:Analgesics / Q000009:adverse effects; D018712:Analgesics, Non-Narcotic / Q000009:adverse effects; D000890:Anti-Infective Agents / Q000009:adverse effects; D018906:Antineoplastic Agents, Alkylating / Q000009:adverse effects; D006801:Humans; D007069:Ifosfamide / Q000009:adverse effects; D007674:Kidney Diseases / Q000139:chemically induced*
D000700:Analgesics; D018712:Analgesics, Non-Narcotic; D000890:Anti-Infective Agents; D018906:Antineoplastic Agents, Alkylating; D007069:Ifosfamide