[The dynamics of the formation of IgG subclasses in Balb/c and CBA mice infected with the LCM, Lassa and Mopeia viruses and their role in diagnosis].
The dynamics of the induction of individual IgG subclasses in BALB/c and CBA mice and their role on the diagnostics of arenaviruses LCM, Lassa and Mopeia was studied. The study demonstrated that in solid-phase enzyme immunoassay (EIA) isotypes IgG2a and IgG2b to virus Mopeia could be used for the differentiation of virus Mopeia from viruses LCM and Lassa, and the antigen of virus Mopeia could be used for the preparation of diagnostic EIA systems not only to nonpathogenic virus Mopeia, but also to pathogenic viruses LCM and Lassa.
Zaĭtseva
V N
VN
Bystrova
S I
SI
Shkolina
T V
TV
Vladyko
A S
AS
D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis* / Q000097:blood; D000915:Antibody Affinity; D001116:Arenaviridae / Q000276:immunology*; D001117:Arenaviridae Infections / Q000175:diagnosis*; D003429:Cross Reactions; D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay; D007114:Immunization; D007074:Immunoglobulin G / Q000096:biosynthesis* / Q000097:blood; D007132:Immunoglobulin Isotypes / Q000096:biosynthesis* / Q000097:blood; D007835:Lassa Fever / Q000175:diagnosis*; D007836:Lassa virus / Q000276:immunology*; D008216:Lymphocytic Choriomeningitis / Q000175:diagnosis*; D008217:Lymphocytic choriomeningitis virus / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D008808:Mice, Inbred CBA
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007132:Immunoglobulin Isotypes