title: A biokinetic model for 137Cs.
abstract: An improved biokinetic model for 137Cs in humans was developed based on an analysis of data obtained from individuals internally contaminated during an accident in Goiania, Brazil, and other data. Seventeen children (ten girls and seven boys 1-10 y old), ten adolescents (four females and six males), and thirty adults, (fifteen females and fifteen males contaminated in the accident in Goiânia contributed to this study. 137Cs retention was determined through periodic measurements in a whole-body counter. In addition to the data on 137Cs retention from these individuals, data from a study on the metabolism of 137Cs in immature, adult, and aged Beagle dogs and data from the literature were used in the formulation of the 137Cs biokinetic model presented. Mathematically, the retention of cesium is described by three exponential terms, and the retention model is based on a step function of body weight. When the ICRP Publication 56 model for cesium was compared to the model suggested in this paper, it was determined that the ICRP model predicts lower effective doses in 5-y-old children and higher effective doses in infants, adolescents, and adults.
authors.affiliation: Instituto de Radioproteção e Dosimetria, Barra da Tijuca, Rio de Janeiro, Brazil.
authors.forename: D R
authors.initials: DR
authors.lastname: Melo
authors.forename: J L
authors.initials: JL
authors.lastname: Lipsztein
authors.forename: C A
authors.initials: CA
authors.lastname: Oliveira
authors.forename: D L
authors.initials: DL
authors.lastname: Lundgren
authors.forename: B A
authors.initials: BA
authors.lastname: Muggenburg
authors.forename: R A
authors.initials: RA
authors.lastname: Guilmette
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D002588:Cesium Radioisotopes / Q000493:pharmacokinetics*; D002648:Child; D002675:Child, Preschool; D004285:Dogs; D005260:Female; D006207:Half-Life; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D011829:Radiation Dosage
chemical_list: D002588:Cesium Radioisotopes