title: An evaluation of neuromuscular reversal with edrophonium in a patient with malathion intoxication.
abstract: We evaluated the neuromuscular reversal with edrophonium using peripheral nerve stimulator and recorder in a patient with malathion intoxication. Edrophonium 10 mg i.v. caused an increase in single twitch tension by 76% of the control during the recovery phase from an acute cholinergic crisis 16 days after ingestion of malathion solution. The present study indicated that edrophonium test seems to be a reliable monitoring in evaluating neuromuscular reversal in the patient with acute malathion insecticide poisoning.
authors.affiliation: Division of Intensive Care Medicine, Tohoku University Hospital, Sendai, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Matsukawa
authors.forename: Y
authors.initials: Y
authors.lastname: Hashimoto
authors.forename: M
authors.initials: M
authors.lastname: Kato
authors.forename: K
authors.initials: K
authors.lastname: Hoshi
authors.forename: D
authors.initials: D
authors.lastname: Satoh
authors.forename: T
authors.initials: T
authors.lastname: Horinouchi
authors.forename: S
authors.initials: S
authors.lastname: Satoh
authors.forename: T
authors.initials: T
authors.lastname: Saishu
mesh_terms: D000328:Adult; D002800:Cholinesterase Inhibitors / Q000506:poisoning*; D004491:Edrophonium; D004558:Electric Stimulation; D005260:Female; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D008294:Malathion / Q000506:poisoning*; D008991:Monitoring, Physiologic; D009119:Muscle Contraction / Q000187:drug effects; D009469:Neuromuscular Junction / Q000187:drug effects* / Q000503:physiopathology*; D010525:Peripheral Nerves / Q000187:drug effects* / Q000503:physiopathology*; D013406:Suicide, Attempted
chemical_list: D002800:Cholinesterase Inhibitors; D007306:Insecticides; D004491:Edrophonium; D008294:Malathion