[Effect of jiawei sijunzi decoction on migrating myoelectric complex in 8 Gy irradiated rats].
The normal intestinal migrating myoelectric complex (MMC) of rats recorded by implanted electrode consists of four phases (phase I, II, III and IV). After 8 Gy of gamma-radiation for 1 hour to 7 days, the MMC cycle in most of the rats were disappeared only phase I or II existed with minute's rhythm. 1 hour or 3 days after radiation, the MMC cycle appeared in a few rats with the phase II shortened significantly (P < 0.05). Results of observation on effect of Jiawei Sijunzi Decoction on MMC after radiation showed the changed phase and cycle of MMC were normalized basically by the medication. These results suggested that the Jiawei Sijunzi decoction could improve the intestinal disturbances caused by radiation, it might be one of the reason of its alleviating effect on the radiation diarrhea.
Chen
G Z
GZ
Institute of Radiation Medicine, Academy of Military Medical Sciences, Beijing.
Fu
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D000818:Animals; D003967:Diarrhea / Q000209:etiology / Q000503:physiopathology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D008297:Male; D016065:Myoelectric Complex, Migrating / Q000187:drug effects*; D011833:Radiation Injuries, Experimental / Q000503:physiopathology*; D051381:Rats; D017208:Rats, Wistar; D014916:Whole-Body Irradiation / Q000009:adverse effects
D004365:Drugs, Chinese Herbal