Human biological decline and mortality rates.
Intercepts on the x (age)-axis of 107 normalized declining human biological functions were determined and assembled in 3 histograms, being placed in increasing order within each decade (10 year period). The histograms were classed accordingly as they contained properties associated with dividing cells, sensory properties and non-dividing cells respectively. Their cumulants were determined, multiple regressions calculated and compared with current death-rates for women and men respectively, for 10 amongst the longest living populations in the World. An alternative verification based on risk theory led to an estimate of an optimal life expectancy of 96 years. The survival curve turns out to be of the form (See text: Formula) where the inner integral represents the cumulant dimension (t') and the outer one age (t"). The premises underlying this study are compatible with the notion of a probable life-span, rather than a fixed one.
Weale
R A
RA
Age Concern Institute of Geneology, King's College London, UK.
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000502:physiology*; D000704:Analysis of Variance; D005260:Female; D006801:Humans; D008017:Life Expectancy; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009026:Mortality; D015203:Reproducibility of Results; D015996:Survival Rate