Hereditary multiple benign cystic epithelioma (multiple trichoepithelioma) with onset at early age.
A mother and a daughter affected with multiple trichoepithelioma were studied. The age of onset of the symptomatology in both was 7-years-old, the daughter being more severely affected than the mother at this age. This early age of onset is an exceptional observation which could be explained by maternal imprinting.
Correa-Cerro
L S
LS
División de Genética, IMSS, Centro Universitario Ciencias de la Salud, Universidad de Guadalajara, Jalisco, Mexico.
García-Cruz
D
D
Sarralde
A
A
Morales-Peralta
E
E
González-Mendoza
A
A
Sánchez-Corona
J
J
D000328:Adult; D002648:Child; D002869:Chromosome Aberrations / Q000235:genetics*; D025063:Chromosome Disorders; D005153:Facial Neoplasms / Q000235:genetics*; D005260:Female; D015870:Gene Expression / Q000502:physiology; D005799:Genes, Dominant / Q000235:genetics*; D006801:Humans; D018295:Neoplasms, Basal Cell / Q000235:genetics*; D009378:Neoplasms, Multiple Primary / Q000235:genetics*; D009386:Neoplastic Syndromes, Hereditary / Q000235:genetics*; D010641:Phenotype; D012878:Skin Neoplasms / Q000235:genetics*