title: [Congenital developmental defects negatively affecting the viability of children of Kursk region: prevalence, pattern, trends].
abstract: The distribution of and time trends in congenital defects of development (CD) influencing viability of children in the Kursk region were studied on the basis of 4517 autopsy reports for the period 1985-1994. A total of 880 children had CD (5.40%). The incidence of CD in towns (6.38%), was higher than in country regions (4.91%), p < 0.001, being the highest in the central parts of the region. Among the stillborns the specific proportion of congenital defects was 14.53%, perinatal deaths occurred in 16.96%, deaths during the 1st year of life in 22.10%. The percentage of multiple congenital defects, the defects of cardiovascular system, developmental anomalies of digestive system, the defects of central nervous system and organs of sense was 39.77, 27.16, 10.11 and 8.30, respectively.
authors.forename: V P
authors.initials: VP
authors.lastname: Ivanov
authors.forename: M I
authors.initials: MI
authors.lastname: Churnosov
authors.forename: A I
authors.initials: AI
authors.lastname: Kirilenko
mesh_terms: D000015:Abnormalities, Multiple / Q000453:epidemiology; D002490:Central Nervous System / Q000002:abnormalities; D000013:Congenital Abnormalities / Q000453:epidemiology* / Q000401:mortality; D004065:Digestive System Abnormalities; D005313:Fetal Death / Q000453:epidemiology; D006330:Heart Defects, Congenital / Q000453:epidemiology; D006801:Humans; D007223:Infant; D007226:Infant Mortality / Q000639:trends*; D007231:Infant, Newborn; D015995:Prevalence; D012423:Rural Health; D012426:Russia / Q000453:epidemiology; D014504:Urban Health