A retrospective study of 13 Oriental children with juvenile dermatomyositis.
This is a retrospective study of 13 Oriental children with juvenile dermatomyositis (JDM). We reviewed data found in the hospital records of children diagnosed to have definite (n = 4), probable (n = 7) and possible (n = 2) JDM who presented over a 10-year period at 4 centres in Singapore and compared our results with the experience of others. We found an overall female preponderance (female to male ratio of 3.3:1) but an equal sex ratio in children below 5 years of age. The majority (92%) had insidious onset and good outcome. Diagnosis was often delayed because of the insidious onset, and because weakness occurred late, was mild or absent. Only one child had an acute presentation and refractory course. She died despite aggressive therapy. Clinical features, complications and mainstay medication used were similar to Western studies.
See
Y
Y
Department of Paediatrics, Alexandra Hospital, Singapore.
Giam
Y C
YC
Chng
H H
HH
D000293:Adolescent; D017677:Age Distribution; D002648:Child; D002675:Child, Preschool; D003882:Dermatomyositis / Q000175:diagnosis / Q000188:drug therapy / Q000201:enzymology*; D004359:Drug Therapy, Combination; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D012008:Recurrence; D012189:Retrospective Studies; D017678:Sex Distribution; D012846:Singapore / Q000453:epidemiology; D016896:Treatment Outcome
D004365:Drugs, Chinese Herbal