Syndrome of inappropriate antidiuretic hormone (SIADH) in an 80-year-old woman given clomipramine.
The author describes the syndrome of inappropriate antidiuretic hormone, with serum sodium decreasing from 137 mEq/L to 122 mEq/L in an 80-year-old woman prescribed clomipramine. The patient's delirium and serum sodium were slow to normalize, prolonging her hospital stay and delaying treatment of her depression.
Sommer
B R
BR
Stanford University Medical Center, CA 94305-5546, USA.
D000368:Aged; D000369:Aged, 80 and over; D002997:Clomipramine / Q000008:administration & dosage / Q000009:adverse effects*; D003693:Delirium / Q000139:chemically induced / Q000175:diagnosis / Q000523:psychology; D003866:Depressive Disorder / Q000139:chemically induced / Q000188:drug therapy* / Q000523:psychology; D003937:Diagnosis, Differential; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000139:chemically induced* / Q000175:diagnosis / Q000523:psychology; D017367:Selective Serotonin Reuptake Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*
D002997:Clomipramine; D017367:Selective Serotonin Reuptake Inhibitors