title: 5-HT receptor classification and nomenclature: towards a harmonization with the human genome.
abstract: Molecular biology has dramatically advanced our knowledge and understanding of receptors for 5-hydroxytryptamine (5-HT). The existence of multiple 5-HT receptors defined using traditional pharmacological and biochemical approaches has now been amply confirmed, but gene products encoding putative "new" 5-HT receptors have also been discovered. In some cases, the absence of suitably selective agonists and antagonists has hampered determination of a physiological role for these gene products. This makes their classification as formally recognised receptors premature.
authors.affiliation: Novartis Pharma Ltd, Basel, Switzerland.
authors.forename: D
authors.initials: D
authors.lastname: Hoyer
authors.forename: G
authors.initials: G
authors.lastname: Martin
mesh_terms: D000818:Animals; D015894:Genome, Human; D006801:Humans; D011985:Receptors, Serotonin / Q000145:classification* / Q000235:genetics*; D009626:Terminology as Topic
chemical_list: D011985:Receptors, Serotonin