The road to the cure of acute lymphoblastic leukemia: a personal perspective.
Acute lymphoblastic leukemia was the first syngeneic systemic malignancy to be cured by chemotherapy (1962). The personal description of the key players and the major innovations are presented by one of those participating in this achievement. The principles developed over the subsequent 30 years have found wide application to the therapy of other systemic malignancies.
Freireich
E J
EJ
University of Texas M.D. Anderson Cancer Center, Houston 77030, USA. efreirei@notes.mdacc.tmc.edu
D000970:Antineoplastic Agents / Q000266:history; D049673:History, 20th Century; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000266:history / Q000628:therapy*; D014481:United States
D000970:Antineoplastic Agents