[Clinical and experimental study on treatment of rotaviral enteritis with qiwei baizhu powder].
Sixty cases of rotaviral enteritis treated with Qiwei Baizhu Powder (QWBZP) revealed a better efficacy than that treated with Oral Rehydration solution (ORS, chi 2 = 6.07, P < 0.05). The content of Na+ and glucose as well as number of patients with positive human rotavirus (HRV) antigen in faeces in QWBZP group were less than that in ORS group (chi 2 = 18.09, P < 0.05). In experimental study, QWBZP was found to be effective in treating HRV enteritis of newborn NIH mice in vivo, as compared with the control groups, the mortality of mice was decreased by 73.3%, the content of Na+ and glucose as well as number of mice with positive HRV antigen in faeces was markedly reduced, the pathological changes of intestine such as the damage of small intestinal mucosa and the exfoliation of intestinal villi were also obviously alleviated.
He
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Hunan Academy of Traditional Chinese Medicine, Changsha.
He
F Z
FZ
Wu
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CR
D000818:Animals; D000956:Antigens, Viral / Q000378:metabolism*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004751:Enteritis / Q000188:drug therapy* / Q000628:therapy / Q000821:virology; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007223:Infant; D007413:Intestinal Mucosa / Q000473:pathology; D008297:Male; D051379:Mice; D012401:Rotavirus / Q000276:immunology*; D012400:Rotavirus Infections / Q000188:drug therapy* / Q000628:therapy
D000956:Antigens, Viral; D004365:Drugs, Chinese Herbal