Precision of the gallbladder ejection fraction obtained with Tc-99m-pyridoxyl-5-methyl-tryptophan (99mTc-PMT) hepatobiliary scintigraphy as compared with the contraction ratio in three-dimensional computed tomography.
The gallbladder ejection fraction (GBEF) obtained with Tc-99m-pyridoxyl-5-methyl-tryptophan (99mTc-PMT) hepatobiliary scintigraphy has been used as a parameter of gallbladder function. To determine the accuracy of GBEF, the relationship with the contraction ratio of the gallbladder (GBCR) obtained with three-dimensional helical computed tomography (3D-CT) was studied.


METHODS
A normal volunteer, 8 patients suffering from cholecystolithiasis and a patient with gallbladder dyskinesia were examined. The percent initial dose (%ID) for the gallbladder and GBEF with hepatobiliary scintigraphy were used to compare the volume of the gallbladder and GBCR which was measured by 3D-CT.


RESULTS
The %ID of the gallbladder was correlated with the volume of the gallbladder by 3D-CT (Y = 1.000X - 1.818, r = 0.928). GBEF was correlated well with GBCR by 3D-CT (Y = 0.916X + 6.296, r = 0.975).


CONCLUSIONS
The %ID of the gallbladder obtained with hepatobiliary scintigraphy may be a good indicator of the volume of the gallbladder. The accuracy of GBEF was confirmed by comparison with 3D-CT examination. GBEF is considered a useful parameter of pathophysiological gallbladder function.
Uchiyama
K
K
Department of Radiology, Showa University Fujigaoka Hospital, Yokohama, Japan.
Kuniyasu
Y
Y
Higashi
S T
ST
Shen
Y
Y
Niio
Y
Y
Hasebe
S
S
Matsuoka
S
S
Shima
H
H
Shinohara
H
H
Takizawa
K
K
Obuchi
M
M
Honda
M
M
Hirata
N
N
D000328:Adult; D000368:Aged; D002765:Cholecystography / Q000379:methods*; D002769:Cholelithiasis / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging* / Q000502:physiology; D005705:Gallbladder Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology; D016473:Gallbladder Emptying; D006801:Humans; D008297:Male; D008875:Middle Aged; D015609:Organotechnetium Compounds; D011759:Pyrrolidines; D011877:Radionuclide Imaging; D013752:Tetracycline; D014057:Tomography, X-Ray Computed / Q000379:methods*
D015609:Organotechnetium Compounds; D011759:Pyrrolidines; C057732:technetium Tc 99m pyrrolidino-methyltetracycline; D013752:Tetracycline