title: [Gas embolism secondary to intraoperative use of hydrogen peroxide].
abstract: Hydrogen peroxide solution (H2O2) is used to irrigate and clean wounds. When applied to tissue hydrogen peroxide decomposes rapidly as a result of the action of catalases, releasing oxygen in the process. High pressure irrigation of the washing of closed cavities can cause serious complications. We report a case of gas embolism arising from the use of hydrogen peroxide during surgery for hydatidosis of the liver. A 64-year-old woman underwent surgery for removal of a hydatid cyst of the liver. When pressurized injection of 10 ml of 3% hydrogen peroxide was applied to the cystic cavity, cardiac arrhythmias were observed, a long with decreased PetCO2, hypotension and a "water mill" heart murmur. Gas embolism was suspected and treatment was instated immediately. Clinical course was good and without complications. We wish to warn against the potential dangers of using peroxide during surgery and of the importance of capnography for early diagnosis of gas embolism.
authors.affiliation: Servicio de Anestesiología, Reanimación y Tratamiento del Dolor, Hospital de Girona Dr. Josep Trueta.
authors.forename: P
authors.initials: P
authors.lastname: García-Velasco
authors.forename: C
authors.initials: C
authors.lastname: García
authors.forename: F
authors.initials: F
authors.lastname: Parramon
authors.forename: A
authors.initials: A
authors.lastname: Villalonga
authors.forename: B
authors.initials: B
authors.lastname: Beltrán de Heredia
mesh_terms: D004618:Embolism, Air / Q000139:chemically induced*; D005260:Female; D006801:Humans; D006861:Hydrogen Peroxide / Q000009:adverse effects*; D007431:Intraoperative Complications / Q000139:chemically induced*; D008875:Middle Aged
chemical_list: D006861:Hydrogen Peroxide