title: Expression of high-affinity 67-kDa laminin receptors in primary breast cancers and metachronous metastatic lesions or contralateral cancers.
abstract: The presence of high-affinity 67-kDa laminin receptors, detected immunohistochemically, was determined on 63 primary breast cancers and on metachronous metastatic lesions or contralateral cancers from the same patients. A disagreement was observed in two-thirds of the cases. In particular, laminin receptor content was significantly lower (P = 0.02) in local recurrences and slightly higher in lymph node metastasis than in the corresponding primary tumours.
authors.affiliation: Oncologia Sperimentale C, Istituto Nazionale per lo Studio e la Cura del Tumori, Milano, Italy.
authors.forename: M G
authors.initials: MG
authors.lastname: Daidone
authors.forename: R
authors.initials: R
authors.lastname: Silvestrini
authors.forename: E
authors.initials: E
authors.lastname: Benini
authors.forename: W F
authors.initials: WF
authors.lastname: Grigioni
authors.forename: A
authors.initials: A
authors.lastname: D'Errico
mesh_terms: D001943:Breast Neoplasms / Q000378:metabolism*; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local / Q000378:metabolism; D009378:Neoplasms, Multiple Primary / Q000378:metabolism*; D017474:Receptors, Laminin / Q000378:metabolism*
chemical_list: D017474:Receptors, Laminin