[Vasculitis and viral infection].
Viruses have been implicated in vasculitis. To determine activity of viral infection associated with vasculitis. 17 patients with vasculitis had been in immunological and antiviral antibodies evaluation. Twenty five healthy controls sex and age matched with hematic biometry (BH) and AA. All subjects were negative to HIV and HBV. Viral activity was demonstrated in eight patients; vascular purpura (5), Takayasu disease (1), polyarteritis nodosa (1), erythema nodosum (1). None subject of control group had IgM activity. Antibodies response of IgG in patients were of lesser intensity than in control group. 14 abnormalities in BH were found in patients and 4 in control group. Immune response in patients, measured by lymphocyte subpopulations and circulating immune complexes was abnormal. In conclusion 47% showed viral activity, but the dominant feature was abnormal immune response in 82%.
Martínez Aguilar
N E
NE
Médico adscrito del servicio de inmunología clínica y alergia. Centro Médico Nacional 20 de Noviembre, ISSSTE.
Guido Bayardo
R
R
Vargas Camaño
M E
ME
Compañ González
D
D
Miranda Feria
A J
AJ
D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D000936:Antigen-Antibody Complex / Q000097:blood; D002648:Child; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000097:blood; D007958:Leukocyte Count; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D016036:Seroepidemiologic Studies; D014657:Vasculitis / Q000097:blood / Q000145:classification / Q000276:immunology / Q000821:virology*; D014777:Virus Diseases / Q000097:blood / Q000150:complications* / Q000453:epidemiology
D000914:Antibodies, Viral; D000936:Antigen-Antibody Complex; D007136:Immunoglobulins