Cell death in the regulation of immune responses.
Cell death is an integral part of the functioning of the immune system. For T cells, potentially autoreactive or 'useless' cells are removed through apoptosis in response to signals (or lack of signals) from their T cell receptor complex. A myriad of proteins that can initiate or protect cells from cell death have recently been identified.
Winoto
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Department of Molecular and Cell Biology, Division of Immunology and Cancer Research Laboratory, Life Science Addition, Berkeley, CA 94720-3200, USA. winoto@uclink2.berkeley.edu.
D000818:Animals; D017209:Apoptosis / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
D011948:Receptors, Antigen, T-Cell