title: New caerin antibacterial peptides from the skin glands of the Australian tree frog Litoria xanthomera. Part 2. Sequence determination using mass spectrometry and associated techniques.
abstract: Mass spectrometric sequencing, enzymic digestion and Edman degradation provide the structures of the two antimicrobial peptides from the skin glands of the Australian tree frog Litoria xanthomera as:- Gly Leu Phe Ser Val Leu Gly Ala Val Ala Lys His Val Leu Pro His Val Val Pro Val Ile Ala Glu Lys Leu (NH2) (caerin 1.6), and Gly Leu Phe Lys Val Leu Gly Ser Val Ala Lys His Leu Leu Pro His Val Ala Pro Val Ile Ala Glu Lys Leu (NH2) (caerin 1.7).
authors.affiliation: Department of Chemistry, University of Adelaide, Australia.
authors.forename: S T
authors.initials: ST
authors.lastname: Steinborner
authors.forename: R J
authors.initials: RJ
authors.lastname: Waugh
authors.forename: J H
authors.initials: JH
authors.lastname: Bowie
authors.forename: M J
authors.initials: MJ
authors.lastname: Tyler
mesh_terms: D000595:Amino Acid Sequence; D029845:Amphibian Proteins; D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis*; D023181:Antimicrobial Cationic Peptides; D001001:Anura / Q000378:metabolism*; D005088:Exocrine Glands / Q000737:chemistry*; D006868:Hydrolysis; D013058:Mass Spectrometry; D008969:Molecular Sequence Data; D010455:Peptides / Q000032:analysis*; D011487:Protein Conformation; D011499:Protein Processing, Post-Translational; D012867:Skin / Q000737:chemistry*
chemical_list: D029845:Amphibian Proteins; D000900:Anti-Bacterial Agents; D023181:Antimicrobial Cationic Peptides; D010455:Peptides; C107616:caerin 1.1, Anura; C107681:caerin 1.6 protein, Litoria; C107682:caerin 1.7 protein, Litoria