The 31-cM region of chromosome 11 including the obesity gene tubby and ATP-sensitive potassium channel genes, SUR1 and Kir6.2, does not contain a major susceptibility locus for NIDDM in 127 non-Hispanic white affected sibships.
Lindner
T
T
Howard Hughes Medical Institute and the Department of Biochemistry and Molecular Biology, The University of Chicago, Illinois 60637, USA.
Gragnoli
C
C
Schulze
J
J
Rietzsch
H
H
Petzold
C
C
Schröder
H E
HE
Cox
N J
NJ
Bell
G I
GI
D018528:ATP-Binding Cassette Transporters; D000368:Aged; D001483:Base Sequence; D002641:Chicago; D002880:Chromosomes, Human, Pair 11 / Q000235:genetics*; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics*; D005190:Family; D008040:Genetic Linkage / Q000235:genetics*; D005819:Genetic Markers; D005838:Genotype; D005858:Germany; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000235:genetics*; D015221:Potassium Channels / Q000235:genetics*; D024661:Potassium Channels, Inwardly Rectifying; D011955:Receptors, Drug / Q000235:genetics*; D064233:Sulfonylurea Receptors; D044465:White People / Q000235:genetics
C577507:ABCC8 protein, human; D018528:ATP-Binding Cassette Transporters; D005819:Genetic Markers; D015221:Potassium Channels; D024661:Potassium Channels, Inwardly Rectifying; D011955:Receptors, Drug; D064233:Sulfonylurea Receptors