Lung transplantation: the experience of the Thoracic Organ Transplantation Centre of Pavia.
Between January 1991 and September 1995 at the Thoracic Organ Transplantation Centre of Pavia, 193 patients entered the waiting list for heart-lung or lung transplantation. Indications for heart-lung transplantation (HLT) were mainly primary or secondary pulmonary vascular diseases. Parenchymal lung diseases were the most frequent reasons for single- (SLT) or double-lung (DLT) transplantation. During the same period, 21 patients underwent HLT, 16 SLT and 14 DLT. Early deaths (within 30 days of surgery) occurred in 2 (10%) HLT, in 3 (19%) SLT, and in 3 (21%) DLT. Nineteen (90%) patients with HLT, 11 (69%) with SLT, and 10 (71%) with DLT survived up to 3 months; and 11 (52%) patients with HLT, 8 (50%) with SLT, and 5 (36%) with DLT survived up to 12 months. At the time of writing, the following patients are still alive: 10 (48%) with HLT, after a mean +/- SEM follow-up of 37.2 +/- 6 (range 28-46) months, 12 (75%) with SLT, after a mean follow-up of 16 +/- 11 (range 1-35) months, and finally 7 (50%) with DLT, after mean follow-up of 14 +/- 9 (range 1-23) months.
Fracchia
C
C
Salvatore Maugeri Foundation IRCCS, Pulmonary Division, Medical Center of Montescano, Italy.
Callegari
G
G
Volpato
G
G
Martinelli
L
L
Rinaldi
M
M
Rampulla
C
C
Ambrosino
N
N
D000328:Adult; D000368:Aged; D005260:Female; D016041:Heart-Lung Transplantation / Q000401:mortality / Q000706:statistics & numerical data; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008171:Lung Diseases / Q000401:mortality / Q000601:surgery*; D016040:Lung Transplantation / Q000401:mortality / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D016019:Survival Analysis