[Diagnosis of Gilbert's syndrome: current status of the fasting test. Review of the literature].
Gilbert's syndrome is a benign, often familial condition characterized by recurrent but asymptomatic jaundice.


OBJECTIVE
To describe the involvement of the reduced caloric intake test, used as a diagnostic test in Gilbert's syndrome.


METHODS
49 patients were diagnosed of Gilbert's syndrome for 6 years. 39 patients took 400 kcal/day for three days. The unconjugated bilirubinemia levels were measured at 0, 24, 48 and 72 hours.


RESULTS
The 82.05% of test were diagnostics at 24 hours (p < 0.001), while it was necessary 48 hours to 100% of tests were diagnostics (p < 0.05). In any case was necessary to determinate the unconjugated bilirubinemia at 72 hours (p < 0.5).


CONCLUSIONS
The best diagnostic efficiency of the reduced caloric intake test is at 48 hours, while the 24 hours determination could be considered diagnostic in a big percentage of the cases. It is not necessary the determination at 72 hours in any case.
Mendoza Hernández
J L
JL
Servicio de Aparato Digestivo, Hospital Clínico Universitario San Carlos.
García Paredes
J
J
Larrubia Marfil
J R
JR
Casimiro Peytavi
C
C
Díaz-Rubio
M
M
D000293:Adolescent; D000328:Adult; D000368:Aged; D001663:Bilirubin / Q000097:blood; D002648:Child; D005215:Fasting; D005260:Female; D005878:Gilbert Disease / Q000097:blood / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged
D001663:Bilirubin