title: Status of the eradication of indigenous wild poliomyelitis in the People's Republic of China.
abstract: A large nationwide outbreak occurred in 1989-1990 in China, in which nearly 10,000 poliomyelitis cases were reported. After two rounds of oral poliovirus vaccine (OPV) supplemental activity in nearly every province in the 1992-1993 winter season, no wild poliovirus was detected in 1993 in 22 provinces in the middle of China that contained 86% of the population. During the first national immunization days (NIDs) conducted in December 1993 and January 1994, 83 million children 0-47 months of age were immunized. In 1994, wild poliovirus was identified in only 6 of 2397 children with stool specimens tested. After a second NID in December 1994 and January 1995, no wild poliovirus was detected in 1995 despite a very high level of virus surveillance. In summary, double-round mass supplemental OPV immunizations in children 0-3 years old in two consecutive winters eliminated wild poliovirus from 23% of the world's population (1.2 billion people).
authors.affiliation: Chinese Academy of Preventive Medicine, Ministry of Public Health, World Health Organization, Beijing, People's Republic of China.
authors.forename: K a
authors.initials: Ka
authors.lastname: Wang
authors.forename: L B
authors.initials: LB
authors.lastname: Zhang
authors.forename: M W
authors.initials: MW
authors.lastname: Otten
authors.forename: X L
authors.initials: XL
authors.lastname: Zhang
authors.forename: C
authors.initials: C
authors.lastname: Yasuo
authors.forename: R Z
authors.initials: RZ
authors.lastname: Zhang
authors.forename: T
authors.initials: T
authors.lastname: Xu
authors.forename: X
authors.initials: X
authors.lastname: Liu
authors.forename: M
authors.initials: M
authors.lastname: Liu
authors.forename: Q L
authors.initials: QL
authors.lastname: Li
authors.forename: J J
authors.initials: JJ
authors.lastname: Yu
authors.forename: Z
authors.initials: Z
authors.lastname: Wang
mesh_terms: D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D006801:Humans; D017589:Immunization Programs; D007223:Infant; D007231:Infant, Newborn; D011051:Poliomyelitis / Q000453:epidemiology* / Q000517:prevention & control*; D017955:Poliovirus / Q000302:isolation & purification; D011055:Poliovirus Vaccine, Oral; D012621:Seasons
chemical_list: D011055:Poliovirus Vaccine, Oral