A syndrome of leukonychia totalis and multiple sebaceous cysts.
We report on a family with leukonychia totalis, koilonychia and multiple sebaceous cysts segregating as an autosomal dominant disorder. This condition has only previously been described in two kindreds, and this report documents the natural course of the disorder and provides further evidence for pancreatitis being an associated syndromic feature.
Slee
J J
JJ
Genetic Services of Western Australia, Margaret Hospital for Children, Perth.
Wallman
I S
IS
Goldblatt
J
J
D000328:Adult; D004814:Epidermal Cyst / Q000235:genetics* / Q000473:pathology; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008875:Middle Aged; D009264:Nails, Malformed / Q000235:genetics* / Q000473:pathology; D010195:Pancreatitis / Q000235:genetics; D010641:Phenotype; D013577:Syndrome