title: On the cardioprotective effect of adenosine.
abstract: In isovolumically perfused Langendorff heart preparations of guinea pigs adenosine-depending on the experimental protocol-more or less could prevent the hypoxia-induced decrease in myocardial adenosine triphosphate [ATP], creatine phosphate [CP], glycogen and increase in lactate, i.e. showed cardioprotection.
authors.affiliation: Department of Pharmacology, Medical University of Debrecen, Hungary.
authors.forename: J Z
authors.initials: JZ
authors.lastname: Szabó
authors.forename: E
authors.initials: E
authors.lastname: Varga
authors.forename: K
authors.initials: K
authors.lastname: Nosztray
authors.forename: A
authors.initials: A
authors.lastname: Ujfalusi
authors.forename: J
authors.initials: J
authors.lastname: Szegi
authors.forename: P
authors.initials: P
authors.lastname: Kovács
authors.forename: A J
authors.initials: AJ
authors.lastname: Szentmiklósi
mesh_terms: D000241:Adenosine / Q000494:pharmacology*; D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D006003:Glycogen / Q000378:metabolism; D006168:Guinea Pigs; D006321:Heart / Q000187:drug effects*; D000860:Hypoxia / Q000378:metabolism; D066298:In Vitro Techniques; D019344:Lactic Acid / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D010725:Phosphocreatine / Q000378:metabolism; D012016:Reference Values
chemical_list: D010725:Phosphocreatine; D019344:Lactic Acid; D000255:Adenosine Triphosphate; D006003:Glycogen; D000241:Adenosine