title: Evaluation of bioelectrical impedance for prospective nutritional assessment in cystic fibrosis.
abstract: We have compared the use of bioelectrical impedance analysis (BIA) with anthropometry for the prediction of changes in total body potassium (TBK) in a group (n = 31) of children with cystic fibrosis. Linear regression analysis showed that TBK was highly correlated (r > 0.93) with height2/impedance, weight, height, and fat-free mass (FFM) estimated from skin-fold measurements. Changes in TBK were also correlated, but less well, with changes in height2/impedance, weight, height, and FFM (r = 0.69, 0.59, 0.44, and 0.40, respectively). The children were divided into two groups: those who had normal accretion of TBK (> 5%/y) and those who had suboptimal accretion of TBK (< 5%/y). Analysis of variance showed that the significant difference in the change in TBK between the groups was detectable by concomitant changes in impedance and weight but not by changes in height, FFM, or weight and height Z scores. The results of this study suggest that serial BIA measures may be useful as a predictor of progressive undernutrition and poor growth in children with cystic fibrosis.
authors.affiliation: Children's Nutrition Research Centre, Royal Children's Hospital, Queensland, Australia.
authors.forename: P C
authors.initials: PC
authors.lastname: Quirk
authors.forename: L C
authors.initials: LC
authors.lastname: Ward
authors.forename: B J
authors.initials: BJ
authors.lastname: Thomas
authors.forename: T L
authors.initials: TL
authors.lastname: Holt
authors.forename: R W
authors.initials: RW
authors.lastname: Shepherd
authors.forename: B H
authors.initials: BH
authors.lastname: Cornish
mesh_terms: D000293:Adolescent; D000886:Anthropometry; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000378:metabolism* / Q000473:pathology; D017097:Electric Impedance; D005260:Female; D006130:Growth Disorders / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology; D006801:Humans; D008297:Male; D015596:Nutrition Assessment; D009748:Nutrition Disorders / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology; D011188:Potassium / Q000378:metabolism*
chemical_list: D011188:Potassium