title: Study of regional cerebral oxygen saturation during percutaneous cardiopulmonary support.
abstract: The purpose of this study was to evaluate the change of regional cerebral oxygen saturation (rSO2) during percutaneous cardiopulmonary support (PCPS) in patients with cardiogenic shock. Fifteen patients with cardiogenic shock were evaluated during PCPS by continuous monitoring of rSO2, systemic venous oxygen saturation (Svo2), and hemodynamics. The brain damage of these patients was also evaluated during and after PCPS. There were 10 males and 5 females. Their ages ranged from 57 to 79 years old (average: 60.0 +/- 14). Two patients were unconscious before PCPS, and 11 received intraaortic balloon pumping (IABP) before PCPS. The change of rSO2 was significantly correlated with the change of Svo2. The average of rSO2 was 64 +/- 3% at the stable hemodynamic condition. The rSO2 with pulsatile PCPS was higher than that with nonpulsatile PCPS. There was no correlation between brain damage and rSO2. The patients with low rSO2 (< 50%) that resulted in poor LV function could not be weaned from PCPS. In conclusion, the continuous monitoring of rSO2 during PCPS could be a useful tool.
authors.affiliation: Department of Second Surgery, Nippon Medical School, Tokyo, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Ninomiya
authors.forename: H
authors.initials: H
authors.lastname: Hosaka
authors.forename: D
authors.initials: D
authors.lastname: Okada
authors.forename: M
authors.initials: M
authors.lastname: Fujii
authors.forename: Y
authors.initials: Y
authors.lastname: Saji
authors.forename: K
authors.initials: K
authors.lastname: Hinokiyama
authors.forename: Y
authors.initials: Y
authors.lastname: Satoh
authors.forename: J
authors.initials: J
authors.lastname: Nejima
authors.forename: M
authors.initials: M
authors.lastname: Takayama
authors.forename: T
authors.initials: T
authors.lastname: Takano
authors.forename: S
authors.initials: S
authors.lastname: Tanaka
mesh_terms: D000368:Aged; D001921:Brain / Q000378:metabolism / Q000473:pathology; D002315:Cardiopulmonary Bypass / Q000592:standards*; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006353:Heart-Assist Devices / Q000592:standards*; D006801:Humans; D007423:Intra-Aortic Balloon Pumping; D008297:Male; D008875:Middle Aged; D010101:Oxygen Consumption / Q000502:physiology*; D011673:Pulsatile Flow; D012770:Shock, Cardiogenic / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome