title: Industrial noise exposure, noise annoyance, and serum lipid levels in blue-collar workers--the CORDIS Study.
abstract: Chronic noise exposure may constitute a risk factor for cardiovascular disease, but the exact mechanism is unclear. The authors studied the association between industrial noise exposure, noise annoyance, and serum lipid/lipoprotein levels in male (n = 1,455) and female (n = 624) blue-collar workers. The authors found that young men (i.e., < or = 44 y of age) exposed to high noise levels (> or = 80 dB[A]) had higher total levels of cholesterol (p = .023) and triglycerides (p = .001), as well as a higher cholesterol ratio (p = .038), than men exposed to low noise levels, even after controlling for confounding variables. In women or in older (> 45 y) men, noise did not affect serum lipid/lipoprotein levels. The authors found no interaction between noise exposure level and noise annoyance (except for high-density lipoprotein in women). However, noise annoyance covaried independently with total cholesterol (p = .022) and high-density lipoprotein (p = .0039) levels in young men and with total cholesterol (p = .035), triglyceride (p = .035), and high-density lipoprotein levels in women (under high noise exposure conditions)(p = .048) levels in women. Noise annoyance and noise exposure levels had an additive effect on cholesterol levels. Young men who scored high on both variables had a 15-mg/dl higher mean cholesterol level (95 % confidence interval [CI] = 7.2, 22.8; p = .0003) than those who scored low on both variables; in women, the corresponding difference was 23 mg/dl (95% CI = 1.5, 42.9; p = .019). The authors concluded that the examination of serum lipid/lipoprotein levels may be useful in studies of the health effects of noise, and particular attention should be paid to noise-annoyed individuals.
authors.affiliation: Occupational Health & Rehabilitation Institute at Loewenstein Hospital, Raanana, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Melamed
authors.forename: P
authors.initials: P
authors.lastname: Froom
authors.forename: E
authors.initials: E
authors.lastname: Kristal-Boneh
authors.forename: D
authors.initials: D
authors.lastname: Gofer
authors.forename: J
authors.initials: J
authors.lastname: Ribak
mesh_terms: D000328:Adult; D000375:Aging / Q000097:blood; D005260:Female; D006801:Humans; D007557:Israel; D008055:Lipids / Q000097:blood*; D008074:Lipoproteins / Q000097:blood; D008297:Male; D008875:Middle Aged; D009623:Noise, Occupational / Q000009:adverse effects* / Q000706:statistics & numerical data; D012307:Risk Factors; D012727:Sex Characteristics
chemical_list: D008055:Lipids; D008074:Lipoproteins