Felodipine use in pregnancy. Report of three cases.
BACKGROUND
Calcium channel blockers are effective agents for the management of chronic hypertension and are being used with increasing frequency. If their safety and efficacy during pregnancy can be documented, women can be counseled to continue their antihypertensive agent during pregnancy. To our knowledge, the use of felodipine, a calcium channel blocker of the dihydropyridine group, during pregnancy has not been described.


METHODS
We report three cases of felodipine use in pregnancy by women with chronic hypertension.


CONCLUSIONS
In women with severe hypertension (diastolic blood pressure > 100 mm Hg) who require pharmacologic treatment of it during pregnancy, felodipine appears to be an acceptable option.
Casele
H L
HL
Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee-Womens Hospital, Pennsylvania 15213-3180, USA.
Windley
K C
KC
Prieto
J A
JA
Gratton
R
R
Laifer
S A
SA
D000328:Adult; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D015736:Felodipine / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy*; D011256:Pregnancy Outcome
D002121:Calcium Channel Blockers; D015736:Felodipine