Odor discrimination of 'cAMP-' and 'IP3-increasing' odorants at high temperature and at high NaCl concentration in turtle olfactory system.
The ability of the turtle olfactory system to discriminate between various cAMP- and IP3-increasing odorants at high temperature and at high NaCl concentration in the olfactory bulb was examined by the cross-adaptation technique. The degrees of discrimination in high [Na+] solution were similar to those in normal Ringer's solution, suggesting that selectivities of receptors coupled with cAMP- and IP3-dependent pathways are similar to those coupled with both cAMP- and IP3-independent pathways. The mean values of the degree of discrimination among the IP3-increasing odorants were higher than those among the cAMP-increasing odorants at high temperature and at high [Na+] concentration. The degrees of discrimination among the IP3-increasing odorants at 40 degrees C were greater than those at 25 degrees C, while those among the cAMP-increasing odorants at 40 degrees C were similar to those at 25 degrees C, suggesting that the features of the receptors of cAMP-increasing odorants are different from those which respond to IP3-increasing odorants.
Kashiwayanagi
M
M
Faculty of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan.
Inamura
K
K
Nagasawa
F
F
Kurihara
K
K
D000222:Adaptation, Physiological / Q000502:physiology; D000818:Animals; D000242:Cyclic AMP / Q000502:physiology*; D004192:Discrimination, Psychological / Q000502:physiology*; D006358:Hot Temperature; D015544:Inositol 1,4,5-Trisphosphate / Q000502:physiology*; D008560:Membrane Fluidity / Q000502:physiology; D009812:Odorants; D012903:Smell / Q000187:drug effects / Q000502:physiology*; D012965:Sodium Chloride / Q000494:pharmacology*; D013268:Stimulation, Chemical; D014426:Turtles / Q000502:physiology*
D012965:Sodium Chloride; D015544:Inositol 1,4,5-Trisphosphate; D000242:Cyclic AMP