title: Paclitaxel formulation as a cause of ethanol intoxication.
abstract: OBJECTIVE
  To report a case of ethyl alcohol intoxication associated with paclitaxel administration.
  
  
  METHODS
  A patient who received a 3-hour paclitaxel infusion for metastatic breast carcinoma and developed symptoms of acute alcohol intoxication. A blood ethanol concentration drawn at the end of the paclitaxel infusion was 97.8 mg/dL (0.098%).
  
  
  CONCLUSIONS
  The amount of alcohol contained in paclitaxel is discussed. A review of the literature revealed one patient series where the highest blood alcohol concentration was one-third that seen in our patient.
  
  
  CONCLUSIONS
  Clinicians should recognize the potential for alcohol intoxication with paclitaxel administration. This is especially pertinent when higher doses are given over a short period of time.
authors.affiliation: Mountain States Tumor Institute, Boise, ID 83712, USA.
authors.forename: D B
authors.initials: DB
authors.lastname: Wilson
authors.forename: T M
authors.initials: TM
authors.lastname: Beck
authors.forename: C A
authors.initials: CA
authors.lastname: Gundlach
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage* / Q000737:chemistry; D001943:Breast Neoplasms / Q000097:blood / Q000188:drug therapy; D000431:Ethanol / Q000097:blood / Q000506:poisoning*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008875:Middle Aged; D017239:Paclitaxel / Q000008:administration & dosage* / Q000737:chemistry; D014677:Pharmaceutical Vehicles; D012997:Solvents
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D014677:Pharmaceutical Vehicles; D012997:Solvents; D000431:Ethanol; D017239:Paclitaxel