Preoperative chemotherapy for congenital hemangiopericytoma and a review of the literature.
OBJECTIVE
Malignant hemangiopericytoma is an uncommon tumor in the pediatric age group. A case of congenital hemangiopericytoma is presented with a review of the literature.


METHODS
A 2-month-old boy presented at birth with an enlarging posterior neck mass. Subsequent histopathologic studies showed findings consistent with hemangiopericytoma. Imaging studies demonstrated an extensive, infiltrative, vascular lesion not readily amenable to surgical resection. A pulmonary metastatic lesion was present.


RESULTS
Combined treatment using vincristine, doxorubicin, and cyclophosphamide given preoperatively resulted in a significant decrease in size of the primary tumor, allowing for resection without complication and resolution of the metastatic lesion.


CONCLUSIONS
Preoperative chemotherapy may have a significant role in the management of infants with malignant hemangiopericytoma.
del Rosario
M L
ML
Division of Pediatric Hematology/Oncology, University of Florida Health Science Center, Gainesville, USA.
Saleh
A
A
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D006258:Head and Neck Neoplasms / Q000151:congenital* / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery; D006393:Hemangiopericytoma / Q000151:congenital* / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery; D006801:Humans; D007223:Infant; D008175:Lung Neoplasms / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008297:Male; D011300:Preoperative Care; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000008:administration & dosage
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide