title: Bilateral pigmented villonodular synovitis in a dog.
abstract: Villonodular synovitis is an extremely rare condition of the synovial membrane in the dog. A 10-year-old, neutered crossbreed was presented with bilateral, progressive hindlimb lameness. Periarticular swelling was noted in both stifle joints. No craniocaudal instability was noted. Radiographs showed massive intra-articular soft tissue proliferation in both joints, with no bony involvement. Arthrocentesis was unsuccessful. Exploratory arthrotomy of the left stifle revealed a greatly thickened, florid, proliferative synovial membrane. An incisional biopsy was carried out and the histopathological diagnosis was chronic active villonodular synovitis. A radical synovectomy was carried out in the right stifle joint 10 days later. Corticosteroid treatment was initiated 10 days after the second surgery and continued for six weeks, with a continuous clinical improvement. Eighteen months after discontinuation of the steroid therapy, the owners reported no recurrence of clinical signs although a mild stiffness was still present.
authors.affiliation: College of Veterinary Medicine, North Carolina State University, Raleign 27606, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Marti
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D004285:Dogs; D005260:Female; D007794:Lameness, Animal / Q000209:etiology; D011859:Radiography; D013264:Stifle / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D000074402:Synovectomy; D013583:Synovial Membrane / Q000187:drug effects / Q000473:pathology; D013586:Synovitis, Pigmented Villonodular / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*
chemical_list: D000305:Adrenal Cortex Hormones