title: [Icelandic moss lozenges in the prevention or treatment of oral mucosa irritation and dried out throat mucosa].
abstract: BACKGROUND
  Icelandic Moss (Cetraria islandica) has been used to treat inflammation and dryness of the pharyngeal mucosa in the naturopathy for many years. It contains substances with protective and antiinflammatory effects for the oral mucosa. The necessary concentration of Icelandic Moss and its therapeutic effectiveness were analysed in this clinical study.
  
  
  METHODS
  Sixty-one patients who recently underwent surgery of nasal septum were evaluated for this randomized study. These patients suffer especially from dryness and inflammation of the oral cavity due to breathing only through the mouth while the nose is permanently closed by a nasal package. Three groups of patients treated with three different concentrations of the active substance were compared, Coating, dryness, and inflammation of the mucosa, lymph nodes, tongue, the tolerance of the drug, and symptoms like hoarseness and sore throat were documented. The oral application was performed from the first to the fifth day after the operation.
  
  
  RESULTS
  The treatment with Icelandic Moss caused a direct reduction of the observed pathological changes. There were no significant differences between the three test groups. A dose of 0.48 g per day (10 Isla-Moos lozenges per day) is a sufficient treatment.
  
  
  CONCLUSIONS
  Icelandic Moss is an advisable therapeutic opportunity without interactions and side effects for the treatment of inflammation of the oral mucosa occurring after nasal surgery, after intubation, and for simple infections of the throat.
authors.affiliation: HNO-Klinik, Westpfalz-Klinikum Kaiserslautern.
authors.forename: C
authors.initials: C
authors.lastname: Kempe
authors.forename: H
authors.initials: H
authors.lastname: Grüning
authors.forename: N
authors.initials: N
authors.lastname: Stasche
authors.forename: K
authors.initials: K
authors.lastname: Hörmann
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D019068:Bryopsida; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use*; D012225:Rhinoplasty; D013280:Stomatitis / Q000188:drug therapy*; D014987:Xerostomia / Q000188:drug therapy*
chemical_list: D000893:Anti-Inflammatory Agents; D010936:Plant Extracts