title: Monoclonal gammopathy in a Dutch warmblood mare.
abstract: A 15-year-old Dutch warmblood mare was presented because of lethargy, which had been present for several weeks, and severe anaemia. Total protein was high and serum electrophoresis revealed a monoclonal peak in the alpha-2 region. Monoclonal immunoglobulin, IgG(T), was detected by immuno-electrophoresis in serum and urine. Postmortem examination revealed a relatively large number of plasmacytoid cells in the bone marrow and a monotonous population of plasmacytoid cells in the spleen. These findings are suggestive of a plasma cell myeloma.
authors.affiliation: Department of Large Animal Medicine and Nutrition, Utrecht University, Faculty of Veterinary Medicine, The Netherlands.
authors.forename: S N
authors.initials: SN
authors.lastname: Geelen
authors.forename: W E
authors.initials: WE
authors.lastname: Bernadina
authors.forename: G C
authors.initials: GC
authors.lastname: Grinwis
authors.forename: H C
authors.initials: HC
authors.lastname: Kalsbeek
mesh_terms: D000740:Anemia / Q000473:pathology / Q000662:veterinary; D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D005260:Female; D006734:Horse Diseases / Q000097:blood / Q000473:pathology* / Q000652:urine; D006736:Horses; D007122:Immunoelectrophoresis / Q000662:veterinary; D007074:Immunoglobulin G / Q000097:blood / Q000652:urine; D010265:Paraproteinemias / Q000097:blood / Q000473:pathology / Q000652:urine / Q000662:veterinary*; D012016:Reference Values; D013154:Spleen / Q000473:pathology
chemical_list: D007074:Immunoglobulin G