title: Realization of a permanent implantable pulsatile impeller heart with magnetically suspended motor.
abstract: A permanent impeller heart that could work for years was once an idea. However, now this idea is turning into reality through the use of the magnetically suspended motor. Recently, with our implantable pulsatile impeller pump, 3 left ventricular assisted calves survived for about 2 months (62, 54, and 46 days, respectively). The termination of the experiments was related to wear of the mechanical bearing, which resulted in vibration of the rotor and pump failure. All the experimental animals were in good condition prior to pump failure. It seemed as if the experiments could have lasted indefinitely if the bearing had not failed. All the hematological and biochemical data of the calves remained in normal or acceptable ranges; neither blood damage nor organ dysfunction of any animal was detected. During autopsy, no severe thrombus formation was found in the pump or vessels although a low dose of heparin (0.5-0.8 g/h) was given to increase the activated coagulation time (ACT) to 1.5-2.0 times its normal value. To solve the problem of bearing wear, a magnetically suspended motor was investigated and applied to the impeller pump. On the opposite sides of a disc connected to the rotor, 2 permanent magnet rings were embedded, one for driving and the other for axial suspension. Because both the driving and suspending coils with iron cores attract the disc, no radial bearing was needed. This newly devised impeller heart promises to have long-term and permanent applications.
authors.affiliation: Institute of Biomedical Engineering, Jiangsu University of Science and Technology, China.
authors.forename: K X
authors.initials: KX
authors.lastname: Qian
authors.forename: M
authors.initials: M
authors.lastname: Zheng
mesh_terms: D000818:Animals; D001794:Blood Pressure; D002417:Cattle; D004562:Electrocardiography; D004868:Equipment Failure; D006353:Heart-Assist Devices / Q000009:adverse effects / Q000592:standards / Q000639:trends; D008280:Magnetics; D011183:Postoperative Complications / Q000209:etiology / Q000401:mortality; D011673:Pulsatile Flow; D013552:Swine