Axon-glia interactions: building a smart nerve fiber.
Myelinated nerve fibers are designed in an optimal manner which requires tuning of conduction time with millisecond precision. This involves the highly coordinated differentiation of axons and myelin-forming glial cells; the nature of the signals involved in this axon-glial cell dance are beginning to be elucidated.
Waxman
S G
SG
Department of Neurology, Yale University School of Medicine, New Haven, Connecticut 06510, USA.
D000818:Animals; D001369:Axons / Q000502:physiology*; D009412:Nerve Fibers / Q000502:physiology; D009457:Neuroglia / Q000502:physiology*