title: [Giant cell tumors of the spine. Report of a case, literature review].
abstract: Giant cell tumors of bone are uncommon in the vertebrae above the sacrum. We report the case of a giant cell tumor of the third lumbar vertebra, revealed by lumbar and radicular pain. X ray, computed tomography and magnetic resonance imaging showed osteolysis of the body and vertebral arch of L3. Histologic evaluation gave a conclusion of a giant cell tumor, grade 2. Spondylectomy of L3 was performed using a combined approach (anterior and posterior) in two stages. The patient had a good functional result without recurrence at three years and six months. A review of the literature indicates that the radiological appearance is nonspecific but shows the extent of the tumor. Diagnosis can be based only on histological features. Radiotherapy could induce malignant transformation. Radical resection limits the risk of recurrence. Total spondylectomy is recommended for giant cell tumors when both the body and arch are involved.
authors.affiliation: Service d'Orthopédie et Traumatologie A, Hôpital Roger Salengro, Centre Hospitalier Universitaire de Lille, France.
authors.forename: P
authors.initials: P
authors.lastname: Laffargue
authors.forename: A
authors.initials: A
authors.lastname: Cotten
authors.forename: B
authors.initials: B
authors.lastname: Cortet
authors.forename: M
authors.initials: M
authors.lastname: Lecomte-Houcke
authors.forename: J
authors.initials: J
authors.lastname: Decoulx
mesh_terms: D000328:Adult; D001860:Bone Plates; D003952:Diagnostic Imaging; D005260:Female; D018212:Giant Cell Tumor of Bone / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008159:Lumbar Vertebrae / Q000601:surgery; D013123:Spinal Fusion / Q000295:instrumentation / Q000379:methods*; D013125:Spinal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery