Mitomycin-C supplemented trabeculectomy, phacoemulsification, and foldable lens implantation.
OBJECTIVE
To evaluate the outcome of combined mitomycin-C filtering surgery, phacoemulsification, and foldable intraocular lens (IOL) implantation.


METHODS
Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.


METHODS
This retrospective study evaluated 182 eyes of 174 patients who had combined mitomycin-C trabeculectomy, phacoemulsification, and insertion of a foldable IOL through a 3.5 mm incision. Success of the combined procedure was defined as intraocular pressure (IOP) below 21 mm Hg, with or without medications, and no serious complication. Success rates were calculated using the Kaplan-Meier actuarial method.


RESULTS
Mean follow-up was 16.7 months +/- 5.4 (SD). The probability of success at 6, 12, 18, and 24 months was 98.3, 95.6, 90.6, and 88.0%, respectively. When compared with preoperatively, visual acuity improved one or more lines in 148 eyes (81.3%) and worsened one or more lines in 15 (8.2%); 111 eyes (61.0%) achieved visual acuity of 20/40 or better. The most frequent complication was posterior capsule opacification requiring capsulotomy, which occurred in 22 cases (12.0%).


CONCLUSIONS
The 1 year and 2 year IOP control rate of combined mitomycin-C filtering procedures and phacoemulsification in glaucoma patients was high.
Yang
K J
KJ
Glaucoma Service, Wills Eye Hospital, Jefferson Medical College, Philadelphia, Pennsylvania 19107, USA.
Moster
M R
MR
Azuara-Blanco
A
A
Wilson
R P
RP
Araujo
S V
SV
Schmidt
C M
CM
D000368:Aged; D002386:Cataract / Q000209:etiology; D002387:Cataract Extraction; D004867:Equipment Design; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D007910:Lenses, Intraocular; D008297:Male; D016685:Mitomycin / Q000627:therapeutic use*; D018918:Phacoemulsification; D011183:Postoperative Complications; D012086:Reoperation; D012189:Retrospective Studies; D014130:Trabeculectomy; D016896:Treatment Outcome; D014792:Visual Acuity
D016685:Mitomycin