title: A robust sequential detection algorithm for cardiac arrhythmia classification.
abstract: In [1] qnd [2] Thakor et al. describe a sequential probability ratio test (SPRT) based on threshold crossing intervals (TCI) for the discrimination of ventricular fibrillation (VF) from ventricular tachycardia (VT). However, in applying their algorithm to data from the MIT-BIH malignant arrhythmia database, we observed some overlap in the distributions of TCI for VF and VT resulting in 16% overall error rate for the discrimination. In this communication, we describe a modified SPRT algorithm, using a new feature dubbed blanking variability (BV) as the basis for discrimination. Using the MIT-BIH database, the preliminary results showed that the proposed method decreases the overall error rate to 5%.
authors.affiliation: Biomedical Engineering Center, Ohio State University, Columbus 43210, USA.
authors.forename: S W
authors.initials: SW
authors.lastname: Chen
authors.forename: P M
authors.initials: PM
authors.lastname: Clarkson
authors.forename: Q
authors.initials: Q
authors.lastname: Fan
mesh_terms: D000465:Algorithms; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D004562:Electrocardiography; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D016011:Normal Distribution; D011336:Probability; D012815:Signal Processing, Computer-Assisted; D017180:Tachycardia, Ventricular / Q000145:classification*; D014693:Ventricular Fibrillation / Q000145:classification*