Pulmonary smooth muscle proliferation occurring after lung transplantation.
We report the first example of smooth-muscle proliferations occurring in an allograft lung implanted in a recipient who had end-stage emphysema. Smooth-muscle proliferations were detected 46 months following transplantation in a 53-year-old woman. The lesions involved the airways and were bronchoscopically undetectable. Posttransplant smooth-muscle tumors have been described in liver transplant patients and are thought to be due to Epstein-Barr virus. Evidence of virus infection was not found in the current case.
Flint
A
A
Department of Pathology, University of Michigan School of Medicine, Ann Arbor 48105-2522, USA.
Lynch
J P
JP
Martinez
F J
FJ
Whyte
R I
RI
D001706:Biopsy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008168:Lung / Q000473:pathology*; D016040:Lung Transplantation / Q000473:pathology*; D008875:Middle Aged; D009130:Muscle, Smooth / Q000473:pathology*; D011656:Pulmonary Emphysema / Q000601:surgery*; D013997:Time Factors