title: The significance of hemispheric localization of ischemic brain lesion for the early prognosis of ischemic brain disease.
abstract: The possibility of early prediction of ischemic brain disease (IBD) is extremely significant for the creation of the individually designed treatment program. The aim of this study was to determine the significance of hemispheric localization of ischemic brain lesion as possible factor for the early prediction of IBD outcome. The study included 170 patients with IBD, whose score of neurologic and functional impairment was determined after admission by using the standard scales. The values of hemorrheological parameters-erythrocyte sedimentation rate (ESR), fibrinogen and alpha 2 globulin were also determined, so as the extensity of ischemic lesion by CT and MR brain examinations. After the treatment, the score of neurologic and functional impairment was also determined and the degree of ischemic disturbance was estimated-transitory ischemic attack (TIA), reversible ischemic attack (RIA) and cerebral infarction. The lower scores were noticed for neurologic and functional impairment, meaning the more severe degree of ischemic disorder with ischemic lesion localization in right cerebral hemisphere (RCH), in acute stage and at the end of treatment. The higher values of ESR, slightly less of fibrinogen and alpha 2 globulin were revealed in the case of ischemic lesion localization in RCH, so as the higher frequency of RCH lesions in percentages connected with the more severe ischemic disorders. It was concluded that the ischemic lesion localization in RCH might be the predictor of poorer IBD outcome.
authors.affiliation: Military Medical Academy, Clinic for Neurology, Belgrade.
authors.forename: D
authors.initials: D
authors.lastname: Dordević
authors.forename: A
authors.initials: A
authors.lastname: Jovicić
authors.forename: R
authors.initials: R
authors.lastname: Raicević
authors.forename: D
authors.initials: D
authors.lastname: Veljancić
mesh_terms: D001799:Blood Sedimentation; D002545:Brain Ischemia / Q000175:diagnosis*; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D011379:Prognosis; D012712:Serum Globulins / Q000032:analysis
chemical_list: D012712:Serum Globulins; D005340:Fibrinogen