[The treatment of Hodgkin's disease by taking into account individual sensitivity to antitumor preparations].
Polychemotherapy as one of the chief modes of treatment of Hodgkin's disease needs to be updated time and time again. Among approaches toward optimization of chemotherapeutic effects of the drug preparations in question is their selection tailored to the individual with regard to the results of the preliminary investigation into sensitivity to cytostatics. At the department of systemic tumor diseases, treatments with regard to individual sensitivity to chemotherapeutic drug preparations were administered to 190 patients with lymphogranulomatosis. The above treatments appeared to be associated with significant improvement of the immediate results, in the patients developing drug resistance included.
Ponomareva
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Kindzel'skiĭ
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D000293:Adolescent; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use*; D004351:Drug Resistance; D004354:Drug Screening Assays, Antitumor / Q000379:methods; D006689:Hodgkin Disease / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D012008:Recurrence