[Early changes in cardiac function and beta-ARs in heart after severe scalds in rat].
The changes in left ventricular function and ventricle beta-adrenoceptors (beta-ARs) were measured in rat undergoing a full thickness scalded burn of skin of 30% total body surface area. The results showed that there were a significant decrease in left ventricular systolic pressure (LVSP), maximum rising and falling rate of left intraventricular pressure (LV +/- dp/dtmax) and density of ventricular beta-ARs. Correlation analysis showed that the change in beta-ARs density correlated with the change in LVSP, LV +/- dp/dtmax positively.
Sun
J
J
Bethune International Peace Hospital, Shijiazhuang.
Song
Y
Y
Li
F
F
D000818:Animals; D002056:Burns / Q000378:metabolism / Q000503:physiopathology*; D005260:Female; D008297:Male; D009206:Myocardium / Q000378:metabolism; D011817:Rabbits; D051381:Rats; D017208:Rats, Wistar; D011943:Receptors, Adrenergic, beta / Q000378:metabolism*; D016277:Ventricular Function, Left
D011943:Receptors, Adrenergic, beta