title: Cerebral blood flow in single and multiple lacunar infarctions.
abstract: OBJECTIVE
  Single and multiple lacunar infarctions may have some difference in underlying diseases and cerebral blood flows. To determine the difference, we investigated underlying diseases and cerebral blood flows in single and multiple lacunar infarctions.
  
  
  METHODS
  Fifteen cases of lacunar infarction, 10 cases of multiple lacunar infarctions, and 16 control subjects were studied. Regional cerebral blood flow was measured within 14 days after stroke onset with the stable xenon CT method.
  
  
  RESULTS
  The rate of association of diabetes mellitus was higher in the multiple lacunar infarctions group than in the single lacunar infarction group. The blood flow in the cerebral cortex was significantly lower in the multiple lacunar infarctions group than in the single lacunar infarction group. The blood flow change by acetazolamide in the cerebral cortex was significantly lower in the multiple lacunar infarctions group than in the single lacunar infarction group.
  
  
  CONCLUSIONS
  There is some difference in underlying diseases and cerebral blood flows between single and multiple lacunar infarctions.
authors.affiliation: Department of Neurology, Nihon University School of Medicine, Tokyo, Japan. LEF00015@niftyserve.or.jp
authors.forename: Y
authors.initials: Y
authors.lastname: Mochizuki
authors.forename: M
authors.initials: M
authors.lastname: Oishi
authors.forename: T
authors.initials: T
authors.lastname: Takasu
mesh_terms: D000086:Acetazolamide; D000437:Alcoholism / Q000150:complications; D002544:Cerebral Infarction / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D002560:Cerebrovascular Circulation; D048909:Diabetes Complications; D004232:Diuretics; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed / Q000379:methods; D014978:Xenon
chemical_list: D004232:Diuretics; D014978:Xenon; D000086:Acetazolamide