title: [Treatment of peripheral arterial embolisms. Our case series and review of the literature].
abstract: Acute arterial obstruction of the limbs represents one of the most frequent events in Emergency Surgery. In 95% of the cases, the cause has to be searched in embolus parting from the heart in patients with rheumatic or fibrillary disease. Currently the two therapeutic methods used for peripheral arterial obstruction are thrombolytic therapy and surgical dysobstruction using Fogarty's catheter. The Authors compare the two methods on the basis of their experience in 129 cases underlying how the thrombolytic therapy (Urokinase, Streptokinase) should be instituted in the early hours from presentation of symptoms, otherwise, the possibility of revascularization will heavily drop. Better results are obtained by positioning a catheter under radiologic guide for intra-arterial infusion. The Authors also believe that up-to-date the surgical approach with Fogarty's catheter represents one of the best procedures, either for its feasibility of for the costs of the thrombolytic therapy. Furthermore, the thrombolysis may be not complete, and account for possible haemorrhagic complications.
authors.affiliation: Istituto di Clinica Chirurgica, Università degli Studi, La Sapienza, Roma.
authors.forename: V
authors.initials: V
authors.lastname: Terrinoni
authors.forename: F
authors.initials: F
authors.lastname: Altilia
authors.forename: G
authors.initials: G
authors.lastname: Bianchi
authors.forename: O
authors.initials: O
authors.lastname: Abate
authors.forename: N
authors.initials: N
authors.lastname: Bellini
authors.forename: G
authors.initials: G
authors.lastname: Imondi
authors.forename: G
authors.initials: G
authors.lastname: Carbone
authors.forename: M
authors.initials: M
authors.lastname: Rengo
mesh_terms: D000208:Acute Disease; D000368:Aged; D000369:Aged, 80 and over; D017128:Embolectomy; D004617:Embolism / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage; D006801:Humans; D007866:Leg / Q000098:blood supply*; D008297:Male; D010960:Plasminogen Activators / Q000008:administration & dosage; D013300:Streptokinase / Q000008:administration & dosage; D015912:Thrombolytic Therapy; D014568:Urokinase-Type Plasminogen Activator / Q000008:administration & dosage
chemical_list: D005343:Fibrinolytic Agents; D013300:Streptokinase; D010960:Plasminogen Activators; D014568:Urokinase-Type Plasminogen Activator