title: [Laparoscopic cholecystectomy and respiratory function].
abstract: A prospective analysis of 58 patients undergoing laparoscopic cholecystectomy was undertaken to assess pulmonary function changes related to the surgical procedure. Pulmonary function tests were performed preoperatively, as well as 24 hrs., and 48 hrs. after operation. Additionally blood gas analysis was assessed 1 hr. and 6 hrs. after the procedure. At 24 hrs. from operation significant decreases in forced vital capacity, forced expiratory volume in 1", and Tidal volume to 72% (p < 0.001), 70% (p < 0.001), and 92% (p < 0.001) of preoperative values respectively were registered. There was a reduction in PaO2 (p < 0.001) and an increase in PaCO2 (p < 0.05) at 24 hrs. An increase in PaCO2 was also observed 1 hr. (p < 0.001) and 6 hrs. (p < 0.05) postoperatively. Blood gas analysis revealed pH value slightly lower than normal at 1 hr. from operation (p < 0.01). The pulmonary function tests returned to preoperative values at 48 hours.
authors.affiliation: Cattedra di IV Patologia Chirurgica, Università degli Studi La Sapienza, Roma.
authors.forename: A
authors.initials: A
authors.lastname: Tocchi
authors.forename: G
authors.initials: G
authors.lastname: Costa
authors.forename: L
authors.initials: L
authors.lastname: Lepre
authors.forename: G
authors.initials: G
authors.lastname: Liotta
authors.forename: G
authors.initials: G
authors.lastname: Mazzoni
mesh_terms: D000328:Adult; D000368:Aged; D002245:Carbon Dioxide / Q000097:blood; D017081:Cholecystectomy, Laparoscopic; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D011184:Postoperative Period; D011446:Prospective Studies; D012119:Respiration / Q000502:physiology*; D013990:Tidal Volume; D013997:Time Factors; D014797:Vital Capacity
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen