title: The aging tendon.
abstract: After maturation tendons undergo many biochemical, cellular, mechanical and pathological changes that bring about a general decline in the structure and function of the tendon. This decline in the aging tendon is characterized by a reduced ability to adapt to environmental stress and loss of tissue homeostasis. The tendon's adaptability to these changes will decide the rate and the success of treatment of a tendon injury. This review examines these changes and also looks at how we can curtail their progression through exercise and lifestyle modification.
authors.affiliation: Department of Anatomy, Trinity College, Dublin, Ireland.
authors.forename: D J
authors.initials: DJ
authors.lastname: Tuite
authors.forename: P A
authors.initials: PA
authors.lastname: Renström
authors.forename: M
authors.initials: M
authors.lastname: O'Brien
mesh_terms: D000375:Aging / Q000502:physiology*; D001696:Biomechanical Phenomena; D016922:Cellular Senescence / Q000502:physiology*; D003094:Collagen / Q000502:physiology*; D004549:Elastin / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D005109:Extracellular Matrix / Q000502:physiology; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D008019:Life Style; D013710:Tendons / Q000473:pathology / Q000502:physiology*
chemical_list: D003094:Collagen; D004549:Elastin