title: Health-related quality of life after ileoanal pull-through evaluation and assessment of new health status measures.
abstract: OBJECTIVE
  Health-related quality of life (HRQL) after proctocolectomy is a critical parameter for management decisions in patients with chronic pancolitis. The aim of this study was to evaluate the HRQL of patients with ileoanal pull-through and to validate new, easy-to-administer HRQL measures.
  
  
  METHODS
  The Sickness Impact Profile (SIP), Short Form 36 (SF-36), Rating Form of Inflammatory Bowel Disease (IBD) Patient Concerns (RFIPC), and the time trade-off (TTO) were used to measure HRQL of pull-through patients. The SF-36 and the RFIPC were validated.
  
  
  RESULTS
  HRQL of patients with ileoanal pull-through was better than that of a national sample of patients with IBD (SIP and RFIPC) and similar to that of a normal population (SF-36). Physical and psychosocial subscales of the SF-36 correlated with the SIP, affirming the construct validity of the SF-36. The RFIPC results correlated with the SIP and SF-36 results, suggesting that it is also a valid health status measure for these patients. TTO results correlated with the physical subscales of the SIP and SF-36, reflecting the impact of physical health on this group.
  
  
  CONCLUSIONS
  HRQL of patients with ileoanal pull-through is excellent. The SF-36 and RFIPC are valid health status measures that can be used by clinicians and researchers in these patients.
authors.affiliation: Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA.
authors.forename: D
authors.initials: D
authors.lastname: Provenzale
authors.forename: M
authors.initials: M
authors.lastname: Shearin
authors.forename: B G
authors.initials: BG
authors.lastname: Phillips-Bute
authors.forename: D A
authors.initials: DA
authors.lastname: Drossman
authors.forename: Z
authors.initials: Z
authors.lastname: Li
authors.forename: W
authors.initials: W
authors.lastname: Tillinger
authors.forename: C M
authors.initials: CM
authors.lastname: Schmitt
authors.forename: R R
authors.initials: RR
authors.lastname: Bollinger
authors.forename: M J
authors.initials: MJ
authors.lastname: Koruda
mesh_terms: D000328:Adult; D003093:Colitis, Ulcerative / Q000523:psychology / Q000601:surgery*; D005069:Evaluation Studies as Topic; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D016737:Proctocolectomy, Restorative / Q000523:psychology*; D011788:Quality of Life; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires