The origin of an EPR signal observed in dithiocarbamate-loaded tissues. Copper(II)-dithiocarbamate complexes account for the narrow hyperfine lines.
We examined the electron paramagnetic resonance spectra of some copper(II)-dithiocarbamate complexes in various media at liquid nitrogen temperature. It is demonstrated that Cu(II)-dithiocarbamate complexes exhibit atypical spectra with narrow hyperfine splitting, and that the dithocarbamates forming a water-insoluble Cu(II) complex are permeable in tissues, while those yielding water-soluble complexes are not.
Suzuki
Y
Y
Division of Bioinorganic Chemistry, Institute for Life Support Technology, Yamagata Technopolis Foundation, Matsuei, Japan.
Fujii
S
S
Tominaga
T
T
Yoshimoto
T
T
Yoshimura
T
T
Kamada
H
H
D000818:Animals; D001923:Brain Chemistry; D003300:Copper / Q000737:chemistry*; D004578:Electron Spin Resonance Spectroscopy; D051381:Rats; D012996:Solutions; D013859:Thiocarbamates / Q000737:chemistry*
D012996:Solutions; D013859:Thiocarbamates; D003300:Copper