title: The right brain hemisphere is dominant in human infants.
abstract: The development of functional brain asymmetry during childhood is confirmed by changes in cerebral blood flow measured at rest using dynamic single photon emission computed tomography. Between 1 and 3 years of age, the blood flow shows a right hemispheric predominance, mainly due to the activity in the posterior associative area. Asymmetry shifts to the left after 3 years. The subsequent time course of changes appear to follow the emergence of functions localized initially on the right, but later on the left hemisphere (i.e. visuospatial and later language abilities). These findings support the hypothesis that, in man, the right hemisphere develops its functions earlier than the left.
authors.affiliation: Hospital F. Joliot, Department of Medical Research, Orsay, France.
authors.forename: C
authors.initials: C
authors.lastname: Chiron
authors.forename: I
authors.initials: I
authors.lastname: Jambaque
authors.forename: R
authors.initials: R
authors.lastname: Nabbout
authors.forename: R
authors.initials: R
authors.lastname: Lounes
authors.forename: A
authors.initials: A
authors.lastname: Syrota
authors.forename: O
authors.initials: O
authors.lastname: Dulac
mesh_terms: D000293:Adolescent; D000328:Adult; D001264:Athetosis / Q000000981:diagnostic imaging / Q000503:physiopathology; D002540:Cerebral Cortex / Q000098:blood supply / Q000254:growth & development* / Q000502:physiology; D002560:Cerebrovascular Circulation / Q000502:physiology; D002648:Child; D002675:Child, Preschool; D004292:Dominance, Cerebral / Q000502:physiology*; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D006261:Headache / Q000000981:diagnostic imaging / Q000503:physiopathology; D006391:Hemangioma / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009207:Myoclonus / Q000000981:diagnostic imaging / Q000503:physiopathology; D003294:Seizures, Febrile / Q000000981:diagnostic imaging / Q000503:physiopathology; D012893:Sleep Wake Disorders / Q000000981:diagnostic imaging / Q000503:physiopathology; D015899:Tomography, Emission-Computed, Single-Photon