Bilateral internal jugular venous thrombosis complicating severe ovarian hyperstimulation syndrome after prophylactic albumin administration.
OBJECTIVE
To report a case of bilateral thrombosis of the internal jugular veins in a patient after controlled ovarian hyperstimulation and IVF.


METHODS
Case report.


METHODS
University-based IVF program.


METHODS
Ovulation induction with gonadotropins, IVF-ET, albumin administration, and therapeutic heparinization.


METHODS
Doppler ultrasound of neck veins.


RESULTS
Severe ovarian hyperstimulation syndrome and bilateral thrombosis of the internal jugular veins occurred despite prophylactic administration of albumin. This was treated successfully with therapeutic heparinization.


CONCLUSIONS
Internal jugular venous thrombosis, a rare complication of ovulation induction with gonadotropins, should be considered in patients with neck pain and swelling.
Moutos
D M
DM
University of Arkansas for Medical Sciences, Department of Obstetrics and Gynecology, Little Rock 72205, USA.
Miller
M M
MM
Mahadevan
M M
MM
D000328:Adult; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D007275:Injections, Intravenous; D007601:Jugular Veins / Q000000981:diagnostic imaging; D016471:Ovarian Hyperstimulation Syndrome / Q000150:complications* / Q000628:therapy; D010062:Ovulation Induction / Q000009:adverse effects*; D012709:Serum Albumin / Q000008:administration & dosage; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D018608:Ultrasonography, Doppler
D005343:Fibrinolytic Agents; D012709:Serum Albumin; D006493:Heparin