title: Postoperative limited volume irradiation in a child with a solitary brain metastasis from Wilms tumor: a case report.
abstract: An 11-year-old boy presented with a solitary cerebral metastasis 2.5 years after initial diagnosis and 4 months after successful combined modality treatment of a stage II recurrent Wilms tumor in the chest. Resection of the brain metastasis was followed by limited volume irradiation with 30.0 Gy total dose. After a follow-up of 2.5 years the boy is in complete remission and shows no neurological or neuropsychological deficits indicating the possibility of curative postoperative radiotherapy of low toxicity and restricted to the tumor site in the presence of solitary brain metastases.
authors.affiliation: Department of Radiotherapy, University of Tübingen, Germany.
authors.forename: R D
authors.initials: RD
authors.lastname: Kortmann
authors.forename: W
authors.initials: W
authors.lastname: Budach
authors.forename: D
authors.initials: D
authors.lastname: Niethammer
authors.forename: E H
authors.initials: EH
authors.lastname: Grote
authors.forename: M
authors.initials: M
authors.lastname: Bamberg
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D002648:Child; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary / Q000601:surgery; D008297:Male; D008479:Mediastinal Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D009367:Neoplasm Staging; D011182:Postoperative Care; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy; D012074:Remission Induction; D016879:Salvage Therapy; D009396:Wilms Tumor / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery