[The application of the pattern visual-evoked potential in the diagnosis and treatment of amblyopia].
OBJECTIVE
To research into the value of the application in the diagnosis and treatment of amblyopia, and to discuss the mechanism of amblyopia.


METHODS
The subjects were divided into three groups: 108 amblyopia eyes; 180 normal eyes and 26 amblyopia eyes during the treatment with Madopar. PVEP was observed with black-white checks pattern-reversal stimulation at several spatial frequencies (30', 60', 90').


RESULTS
P1 latency of the amblyopia eyes prolongs at the high frequency (30' angle of view), in which the occurrence rate of abnormal PVEP is 68.5%. Through detecting PVEP during the treatment of amblyopia with Madopar, we found P1 latency shortened and amplitude increased (P < 0.05).


CONCLUSIONS
It is better to use P1 latency to observe the visual function of patients with amslyopia with stimulation at 30' angle of view. PVEP is an important objective index in diagnosis and evaluating the curative effect of amblyopia.
Shao
C
C
Department of Physiology, Xingjiang Medical College, China.
Sun
Y
Y
Han
W
W
Pu
L
L
Zhang
Y
Y
Gao
L
L
Yang
H
H
D000293:Adolescent; D000328:Adult; D000550:Amblyopia / Q000175:diagnosis* / Q000188:drug therapy; D001545:Benserazide / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D015259:Dopamine Agents / Q000627:therapeutic use; D004338:Drug Combinations; D005074:Evoked Potentials, Visual; D005260:Female; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008297:Male
D015259:Dopamine Agents; D004338:Drug Combinations; C005177:benserazide, levodopa drug combination; D007980:Levodopa; D001545:Benserazide