Population statistics of protein structures: lessons from structural classifications.
Structural classifications aid the interpretation of proteins by describing degrees of structural and evolutionary relatedness. They have also recently revealed strikingly skewed distributions at all levels; for example, a small number of folds are far more common than others, and just a few superfamilies are known to have diverged widely. The classifications also provide an indication of the total number of superfamilies in nature.
Brenner
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Structural Biology Centre, National Institute for Bioscience and Human-Technology, Ibaraki, Japan. brenner@hyper.stanford.edu
Chothia
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Hubbard
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D001665:Binding Sites; D019143:Evolution, Molecular; D011487:Protein Conformation; D017510:Protein Folding; D011506:Proteins / Q000737:chemistry* / Q000145:classification* / Q000378:metabolism
D011506:Proteins