Nucleotide sequence of a Drosophila melanogaster cDNA encoding a calnexin homologue.
A cDNA which encodes a calnexin (Cnx)-like protein from Drosophila melanogaster has been characterized. The deduced amino acid sequence shares several regions of homology with Cnx from other sources with two conserved motifs each repeated four times. The gene was found to be transcribed in various tissues and at all developmental stages. We have mapped the gene at chromosomal position 99A and we have also mapped the related gene coding for Drosophila calreticulin at 85E.
Christodoulou
S
S
Genetics Laboratory, Department of Biochemistry, Oxford University, UK.
Lockyer
A E
AE
Foster
J M
JM
Hoheisel
J D
JD
Roberts
D B
DB
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015152:Blotting, Northern; D002135:Calcium-Binding Proteins / Q000737:chemistry / Q000235:genetics*; D037281:Calnexin; D037282:Calreticulin; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D017124:Conserved Sequence; D018076:DNA, Complementary; D004331:Drosophila melanogaster / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental; D017403:In Situ Hybridization; D019476:Insect Proteins / Q000737:chemistry / Q000235:genetics; D018832:Molecular Chaperones / Q000737:chemistry; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000032:analysis; D012091:Repetitive Sequences, Nucleic Acid; D012261:Ribonucleoproteins / Q000737:chemistry / Q000235:genetics
D002135:Calcium-Binding Proteins; D037282:Calreticulin; D018076:DNA, Complementary; D019476:Insect Proteins; D018832:Molecular Chaperones; D012333:RNA, Messenger; D012261:Ribonucleoproteins; D037281:Calnexin