title: [Acute Weston Hurst necrotizing hemorrhagic leukoencephalitis].
abstract: The clinical and pathological findings of a 43-year-old woman, diagnosed as having acute hemorrhagic leukoencephalitis at postmortem examination, are presented. The acute hemorrhagic leukoencephalitis affects mainly young adults and is the most fulminant from of demyelinating disease. It is frequently preceded by a respiratory infection. Diagnosis is facilitated by CT scanning and MRI, which reveal the massive lesion in the cerebral white matter. Many cases terminate fatally in 2 or 4 days, but in others survival is longer. The pathological findings are distinctive.
authors.affiliation: Service de Neurochirurgie, CHU Timone-Marseille.
authors.forename: A
authors.initials: A
authors.lastname: Donnet
authors.forename: H
authors.initials: H
authors.lastname: Dufour
authors.forename: D
authors.initials: D
authors.lastname: Gambarelli
authors.forename: N
authors.initials: N
authors.lastname: Bruder
authors.forename: J F
authors.initials: JF
authors.lastname: Pellissier
authors.forename: F
authors.initials: F
authors.lastname: Grisoli
mesh_terms: D000208:Acute Disease; D000328:Adult; D001921:Brain / Q000473:pathology; D005260:Female; D006801:Humans; D004684:Leukoencephalitis, Acute Hemorrhagic / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy