title: Radiotherapy of incompletely resected, moderately differentiated mast cell tumors in the dog: 37 cases (1989-1993).
abstract: Thirty-seven dogs with moderately differentiated, cutaneous mast cell tumors had incomplete surgical excisions as determined by histopathology, but no gross evidence of tumor. All dogs were irradiated to a total dose of between 46.2 and 48.0 Gy using either an orthovoltage source (n = 20) or a linear accelerator (megavoltage) (n = 17). Radiation was delivered to an area bordered by margins of 3 cm or greater around the surgical scar. The mast cell tumors had not recurred in 97% of dogs by one year after radiation therapy and had not recurred in 93% of dogs by three years after radiation. Both orthovoltage and megavoltage radiation provide excellent local control of moderately differentiated mast cell tumors in dogs.
authors.affiliation: Department of Small Animal Medicine, Tufts University School of Veterinary Medicine, North Grafton, Massachusetts 01536, USA.
authors.forename: A E
authors.initials: AE
authors.lastname: Frimberger
authors.forename: A S
authors.initials: AS
authors.lastname: Moore
authors.forename: S M
authors.initials: SM
authors.lastname: LaRue
authors.forename: J M
authors.initials: JM
authors.lastname: Gliatto
authors.forename: A E
authors.initials: AE
authors.lastname: Bengtson
mesh_terms: D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D062109:Dermatologic Surgical Procedures; D004283:Dog Diseases / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D004285:Dogs; D004307:Dose-Response Relationship, Radiation; D005260:Female; D008297:Male; D012515:Mast-Cell Sarcoma / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects / Q000662:veterinary; D012867:Skin / Q000473:pathology / Q000528:radiation effects; D012878:Skin Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*