The aging tendon.
After maturation tendons undergo many biochemical, cellular, mechanical and pathological changes that bring about a general decline in the structure and function of the tendon. This decline in the aging tendon is characterized by a reduced ability to adapt to environmental stress and loss of tissue homeostasis. The tendon's adaptability to these changes will decide the rate and the success of treatment of a tendon injury. This review examines these changes and also looks at how we can curtail their progression through exercise and lifestyle modification.
Tuite
D J
DJ
Department of Anatomy, Trinity College, Dublin, Ireland.
Renström
P A
PA
O'Brien
M
M
D000375:Aging / Q000502:physiology*; D001696:Biomechanical Phenomena; D016922:Cellular Senescence / Q000502:physiology*; D003094:Collagen / Q000502:physiology*; D004549:Elastin / Q000502:physiology*; D015444:Exercise / Q000502:physiology*; D005109:Extracellular Matrix / Q000502:physiology; D006706:Homeostasis / Q000502:physiology; D006801:Humans; D008019:Life Style; D013710:Tendons / Q000473:pathology / Q000502:physiology*
D003094:Collagen; D004549:Elastin