title: Earliest evidence for arthrogryposis multiplex congenita or Larsen syndrome?
abstract: A sixteenth-century illustrated pamphlet from Great Britain suggests that documentary evidence may permit accurate diagnosis of pathological conditions in earlier societies. The document is of particular importance, since the presented congenital abnormalities, including cleft lip, spina bifida cystica, genu recurvatum, and talipes deformity are reported rarely in archaeological skeletal material. It is suggested that the combination of abnormalities may represent the earliest case of arthrogryposis multiplex congenita or Larsen syndrome.
authors.affiliation: Canterbury Archaeological Trust, Kent, UK.
authors.forename: T
authors.initials: T
authors.lastname: Anderson
mesh_terms: D000015:Abnormalities, Multiple / Q000266:history*; D001176:Arthrogryposis / Q000266:history*; D002971:Cleft Lip / Q000266:history; D002972:Cleft Palate / Q000266:history; D005532:Foot Deformities, Congenital / Q000266:history; D049669:History, 16th Century; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008488:Medical Illustration / Q000266:history; D013577:Syndrome; D006113:United Kingdom