title: The antimicrobial activity of endodontic sealers to anaerobic bacteria.
abstract: The effect of five root canal sealers and two root canal dressing materials on the growth of three anaerobic bacteria associated with endodontic infections was determined using the agar diffusion inhibitory test. Samples of the following endodontic sealers (Apexit, Ketac-Endo, Roth Sealer, Sealapex and Tubliseal) and root canal dressing materials (Pulpdent and Root-cal) were incubated for 48 h with the following anaerobic bacteria: Capnocytophaga ochracea, Porphyromonas gingivalis and Peptostreptococcus micros. Statistically significant zones of bacterial growth inhibition for all the bacteria tested were observed in descending order of antimicrobial activity: Roth Sealer, Ketac-Endo, Tubliseal, Apexit and Sealapex. Root-cal and Pulpdent also showed statistically significant antimicrobial activity, but only to Capnocytophaga ochracea, not to the other two bacteria tested, with Pulpdent being the least active.
authors.affiliation: Department of Conservative Dentistry, Dental School, University of Dundee, UK.
authors.forename: A
authors.initials: A
authors.lastname: Abdulkader
authors.forename: R
authors.initials: R
authors.lastname: Duguid
authors.forename: E M
authors.initials: EM
authors.lastname: Saunders
mesh_terms: D001421:Bacteria, Anaerobic / Q000187:drug effects*; D002126:Calcium Hydroxide / Q000494:pharmacology; D002206:Capnocytophaga / Q000187:drug effects; D005899:Glass Ionomer Cements / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D010462:Peptostreptococcus / Q000187:drug effects; D016966:Porphyromonas gingivalis / Q000187:drug effects; D012387:Root Canal Filling Materials / Q000494:pharmacology*; D012459:Salicylates / Q000494:pharmacology; D015035:Zinc Oxide-Eugenol Cement / Q000494:pharmacology
chemical_list: C074418:Apexit; D005899:Glass Ionomer Cements; C074934:Ketac Endo; D012387:Root Canal Filling Materials; C106725:Rootcal; D012459:Salicylates; D015035:Zinc Oxide-Eugenol Cement; C055601:Sealapex; C029777:Pulpdent; C095719:Roth's 811 sealer; C048769:tubliseal; D002126:Calcium Hydroxide