Transporters of nucleotide sugars, nucleotide sulfate and ATP in the Golgi apparatus.
Proteins and glycolipids are glycosylated, sulfated and phosphorylated in the lumen of the Golgi apparatus. The nucleotide substrates of these reactions must first be translocated from the cytosol into the Golgi lumen by specific transporters (antiporters). These are hydrophobic, transmembrane spanning proteins that appear to regulate post-translational modifications in the Golgi lumen.
Abeijon
C
C
Department of Biochemistry and Molecular Biology, University of Massachusetts Medical Center, Worcester 01655, USA.
Mandon
E C
EC
Hirschberg
C B
CB
D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D017920:Antiporters / Q000737:chemistry / Q000378:metabolism*; D001692:Biological Transport; D050260:Carbohydrate Metabolism; D004721:Endoplasmic Reticulum / Q000378:metabolism; D006031:Glycosylation; D006056:Golgi Apparatus / Q000378:metabolism*; D009154:Mutation; D009711:Nucleotides / Q000378:metabolism*; D010766:Phosphorylation; D013431:Sulfates / Q000378:metabolism
D017920:Antiporters; D009711:Nucleotides; D013431:Sulfates; D000255:Adenosine Triphosphate