title: Osteoregenerative lateral suboccipital craniectomy using fibrin glue.
abstract: This report describes a simple technique of cranioplasty for suboccipital craniectomy and the results of a clinical study to assess the effects of fibrin glue on regeneration of the skull. Cranioplasty using a mixture of autologous bone chips and human allogenic fibrin glue was performed in 31 patients who received lateral suboccipital craniectomy. Long-term observations with three-dimensional CT showed satisfactory reconstruction of the mastoid-occipital bone plate in 25 patients (81%); among them, a nearly complete reconstruction of the occipital bone (plate) was found in 14 patients. Regeneration of the bone began 6 months after surgery on the inner surface, adjacent to the dura mater. In conclusion, the present technique provides a new simple method to restore an autologous bone plate in a cranial defect made by piecemeal craniectomy.
authors.affiliation: Department of Neurosurgery, University of Hokkaido School of Medicine, Sapporo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Sawamura
authors.forename: S
authors.initials: S
authors.lastname: Terasaka
authors.forename: N
authors.initials: N
authors.lastname: Ishii
authors.forename: M
authors.initials: M
authors.lastname: Tada
authors.forename: H
authors.initials: H
authors.lastname: Abe
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001861:Bone Regeneration / Q000502:physiology*; D016025:Bone Transplantation; D003399:Craniotomy / Q000379:methods*; D005155:Facial Nerve Diseases / Q000601:surgery*; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008297:Male; D008875:Middle Aged; D009408:Nerve Compression Syndromes / Q000601:surgery*; D009464:Neuroma, Acoustic / Q000601:surgery*; D009777:Occipital Bone / Q000000981:diagnostic imaging / Q000601:surgery; D011183:Postoperative Complications / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
chemical_list: D015718:Fibrin Tissue Adhesive