[Effects of electret and Ligusticum wallichii (chuangxiong) on the functional recovery of muscle grafts].
The aim of this study was to evaluate the effects of electret and Ligusticum wallichii (Chuangxiong, a traditional Chinese herb medicine) on the functional recovery of muscle grafts. Twenty-eight adult dogs were divided into 4 groups with each consisting of 7 animals. After orthotopical transplantation of bilateral rectus femoris muscle with neurovascular anastomosis, group A received electret local implant, group B received Chuangxiong injection, group C received both electret local implant and Chuangxiong injection and group D was used as control. The results showed that the functional recovery of the transplanted rectus femoris muscle in group A and B was better than group D while group C was the best. At 22 postoperative weeks, the recovery rate of maximal tetanic tension was 64.94 +/- 3.82% in group c: 57.68 +/- 1.67% in group A, 53.64 +/- 3.82% in group B and 47.99 +/- 2.21% in group D (P < 0.05). The structural recovery of the transplanted muscle in group C was closest to the normal.
Jiang
H
H
Department of Plastic Surgery, Changhai Hospital, Second Military Medical University, Shanghai.
Guo
E
E
Miao
X
X
D000200:Action Potentials; D000818:Animals; D004285:Dogs; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D004574:Electromagnetic Fields; D005260:Female; D008297:Male; D018482:Muscle, Skeletal / Q000294:innervation / Q000503:physiopathology / Q000637:transplantation*; D019736:Prostheses and Implants
D004365:Drugs, Chinese Herbal