title: Nail lichen striatus: clinical features and long-term follow-up of five patients.
abstract: BACKGROUND
  Nail involvement in lichen striatus (LS) is uncommon and has always been reported in association with typical skin lesions.
  
  
  OBJECTIVE
  We attempted to characterize the clinical and pathologic features and the long-term prognosis of nail LS.
  
  
  METHODS
  Five cases of LS of the nail including three cases with exclusive nail involvement were evaluated and the literature reviewed.
  
  
  RESULTS
  Biopsy specimens showed a moderately dense bandlike lymphohistiocytic infiltrate affecting the proximal nailfold, the nail bed, and the nail matrix dermis. Exocytosis with slight spongiosis, focal hypergranulosis, and dyskeratotic cells were detectable in the nail matrix epithelium. Spontaneous regression of the onychodystrophy occurred after 4 to 12 months from the time of diagnosis (mean, 8.4 months).
  
  
  CONCLUSIONS
  Nail LS is not necessarily associated with skin lesions but can also be an isolated finding. The diagnosis of nail LS should be strongly suspected when a child or a young patient presents with lichen planus-like nail abnormalities localized to the lateral or medial portion of a single nail.
authors.affiliation: Department of Dermatology, University of Bologna, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Tosti
authors.forename: A M
authors.initials: AM
authors.lastname: Peluso
authors.forename: C
authors.initials: C
authors.lastname: Misciali
authors.forename: N
authors.initials: N
authors.lastname: Cameli
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D005533:Foot Dermatoses / Q000150:complications / Q000473:pathology; D006229:Hand Dermatoses / Q000150:complications / Q000473:pathology; D006801:Humans; D017512:Lichenoid Eruptions / Q000150:complications* / Q000473:pathology; D008297:Male; D009260:Nail Diseases / Q000150:complications / Q000473:pathology*; D009262:Nails / Q000473:pathology