title: CSF/blood glucose ratio and other prognostic indices in pyogenic meningitis.
abstract: Fifty cases of pyogenic meningitis were examined for various prognostic indices, especially cerebrospinal fluid (CSF)/blood glucose ratio. Overall mortality was 40%. Age below one year and depressed level of consciousness were associated with high mortality. Illness of more than 7 days, presence of associated illness and absence of neck rigidity were not found to be statistically significant factors associated with higher mortality. CSF leucocyte count of more than 1000 cells/cmm and CSF protein more than 500 mg/dl were statistically significant factors associated with higher mortality. In cases of CSF glucose level below 20 mg/dl and CSF/blood glucose ratio below 0.2, the increase in mortality was highly significant. CSF/blood glucose ratio in cases who recovered was much higher than those who died. CSF/blood glucose ratio increased to normal in cases who recovered but remained low in cases who expired.
authors.affiliation: Department of Paediatrics, Shri MP Shah Medical College, Jamnagar.
authors.forename: B B
authors.initials: BB
authors.lastname: Javadekar
authors.forename: M D
authors.initials: MD
authors.lastname: Vyas
authors.forename: I S
authors.initials: IS
authors.lastname: Anand
mesh_terms: D001786:Blood Glucose / Q000032:analysis*; D002675:Child, Preschool; D005260:Female; D005947:Glucose / Q000134:cerebrospinal fluid*; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D008297:Male; D008581:Meningitis / Q000097:blood / Q000134:cerebrospinal fluid / Q000401:mortality*; D011237:Predictive Value of Tests; D011379:Prognosis; D013492:Suppuration
chemical_list: D001786:Blood Glucose; D005947:Glucose