[Effectiveness of peroral application of a new immunocorrective agent of natural origin].
Data on peroral application of new peptide origin immunocorrector from nervous tissue of hydrobionts are cited. It has been established that immunological gangliin activity, perorally introduced, is close to that being applied parenterally. This drug comprises a soft immunocorrector that is expressed by humoral and cellular factor strengthening of immunity, increasing induces of phagocynosis of PMNC and sells SMPh. Peroral gangliin introduction protects 50-60% of mice from fatal coli-infection. Gangliin availability to be taken perorally opens the door to its wide application as food addition.
Epshteĭn
L M
LM
Borovskaia
G A
GA
Levachev
M M
MM
Gazha
A K
AK
Besednova
N N
NN
Iushkova
T A
TA
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000284:Administration, Oral; D000818:Animals; D000917:Antibody Formation / Q000187:drug effects; D004353:Drug Evaluation, Preclinical; D006168:Guinea Pigs; D006403:Hematologic Tests; D007111:Immunity, Cellular / Q000187:drug effects; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009479:Neuropeptides / Q000627:therapeutic use*; D010455:Peptides / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar
D000276:Adjuvants, Immunologic; D009479:Neuropeptides; D010455:Peptides; C106447:gangliin