title: [Prospective study of 288 cases of acute appendicitis during childhood: characteristics in preschool children].
abstract: OBJECTIVE
  The purpose of this study was to verify that preschool children with acute appendicitis show some clinical characteristics which, associated with the faster evolution of the infection at this age, result in a higher incidence of perforations, peritonitis and complications.
  
  
  METHODS
  A group of 288 children between 9 months and 17 years of age with acute appendicitis was studied over a 17-month period, ending July 1993. They were divided into two age groups: Group I (< 5 years: n = 45) and Group II (5 or more years: n = 243). Comparisons between clinical, laboratory and radiological findings, appendiceal pathology, microbiology and complications were made.
  
  
  RESULTS
  Children fro Group I showed a higher incidence of perforations (29% vs 7.8%), peritonitis (69% vs 36%), appendiceal masses (37% vs 10.2%), positive cultures (66% vs 18%) and complications (24% vs 9.8%) than those from Group II. All differences were found to be significant (p < 0.05). Children from Group I more frequently showed a set of clinical characteristics forming an atypical picture consisting of: 1) Diffuse abdominal pain (69% vs 30%); 2) Associated infections with non-specific symptoms (33% vs 11.5%); 3) Previous therapy with antimicrobial agents (40% vs 9.8%); 4) X-ray findings compatible with gastroenteritis (27% vs 7.4%); and 5) Inability of the child to specify the intensity and location of pain.
  
  
  CONCLUSIONS
  All these factors justified the delay in the diagnosis and its significant relationship with the higher incidence of peritonitis in this age group.
authors.affiliation: Servicio de Cirugía Pediatrica, Hospital Niño Jesús, Madrid.
authors.forename: M
authors.initials: M
authors.lastname: Alvarez Bernaldo de Quirós
authors.forename: N
authors.initials: N
authors.lastname: Sanz Villa
authors.forename: M J
authors.initials: MJ
authors.lastname: Cortés Gómez
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D001064:Appendicitis / Q000150:complications / Q000175:diagnosis*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D016343:Monitoring, Intraoperative; D010538:Peritonitis / Q000209:etiology / Q000382:microbiology; D011446:Prospective Studies; D012189:Retrospective Studies; D012422:Rupture, Spontaneous / Q000209:etiology