title: The value of hysteroscopic exploration for abnormal uterine bleeding.
abstract: OBJECTIVE
  To determine sensitivity, specificity, positive predictive value, negative predictive value, and global diagnostic precision of hysteroscopic exploration in the diagnosis of endometrial hyperplasia and adenocarcinoma in women with abnormal uterine bleeding.
  
  
  METHODS
  Retrospective analysis.
  
  
  METHODS
  University-affiliated hospital.
  
  
  METHODS
  One thousand three hundred ninety-eight patients with abnormal uterine bleeding, 57.3% premenopausal and 42.6% postmenopausal.
  
  
  METHODS
  Diagnostic hysteroscopy and subsequent dilatation and curettage.
  
  
  RESULTS
  Endometrium was classified hysteroscopically as normal, atrophic, endometrial hyperplasia, and endometrial carcinoma. Histopathologic diagnosis was performed to determine the efficacy of hysteroscopy in diagnosing endometrial hyperplasia and adenocarcinoma. For endometrial hyperplasia in premenopausal women, sensitivity was 71.8%, specificity 96.4%, and global diagnostic precision 92.5%; in postmenopausal women, respective figures were 85. 1%, 100%, and 97.3%. For diagnosing adenocarcinoma in premenopausal patients, hysteroscopy was 100% sensitive, with specificity 99.4% and global diagnostic precision 99.5%; in postmenopausal women, respective figures were 100%, 99.4%, and 99.5%.
  
  
  CONCLUSIONS
  In women with abnormal uterine bleeding, diagnostic hysteroscopy is a basic tool that allows precise diagnosis of endouterine lesions such as polyps and submucous myomas. It also is highly accurate for evaluating endometrial adenocarcinoma and hyperplasia.
authors.affiliation: School of Medicine, "Puerto Real" University Hospital, Cadiz, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Torrejon
authors.forename: J J
authors.initials: JJ
authors.lastname: Fernandez-Alba
authors.forename: I
authors.initials: I
authors.lastname: Carnicer
authors.forename: A
authors.initials: A
authors.lastname: Martin
authors.forename: C
authors.initials: C
authors.lastname: Castro
authors.forename: J
authors.initials: J
authors.lastname: Garcia-Cabanillas
authors.forename: J
authors.initials: J
authors.lastname: Rodriguez-Cornejo
authors.forename: L J
authors.initials: LJ
authors.lastname: Moreno
authors.forename: R
authors.initials: R
authors.lastname: Comino
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis; D000328:Adult; D004107:Dilatation and Curettage; D004714:Endometrial Hyperplasia / Q000150:complications / Q000175:diagnosis*; D016889:Endometrial Neoplasms / Q000150:complications / Q000175:diagnosis*; D004717:Endometrium / Q000473:pathology; D005260:Female; D006801:Humans; D015907:Hysteroscopy; D008875:Middle Aged; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014592:Uterine Hemorrhage / Q000175:diagnosis / Q000209:etiology*