Inhibin assays of ovarian cyst liquid obtained by needle aspiration may allow differential diagnosis between functional and organic cysts.
Radioimmunoassays of estradiol, CA125 and inhibin were carried out on ovarian cyst fluid samples. The samples were taken from ten women with functional cysts and 15 women with organic cysts. Statistical analysis shows that estradiol and inhibin assays allows satisfactory differential diagnosis between functional and organic cysts. However, the inhibin assay provides more precise results and appears to be a more reliable marker than estradiol. The differential diagnosis between the two types of cyst would indicate the use of coelioscopic surgery especially in the case of organic cysts, avoiding unnecessary risks for patients with functional cysts.
Binelli
C
C
Service de Gynécologie-Obstétrique, Angers, France.
Chretien
M F
MF
Yves
G
G
Kanaya
M
M
Alain
D
D
D000328:Adult; D001707:Biopsy, Needle; D001826:Body Fluids / Q000737:chemistry*; D018394:CA-125 Antigen / Q000032:analysis*; D003937:Diagnosis, Differential; D004958:Estradiol / Q000032:analysis*; D005260:Female; D006801:Humans; D007265:Inhibins / Q000032:analysis*; D008875:Middle Aged; D010048:Ovarian Cysts / Q000737:chemistry / Q000175:diagnosis*; D011863:Radioimmunoassay; D012189:Retrospective Studies
D018394:CA-125 Antigen; D004958:Estradiol; D007265:Inhibins