Binary synthesis of multicomponent peptide mixtures by the portioning-mixing technique.
By introducing a new operation (non-coupling), our portioning-mixing method has become suitable for preparing binary peptide libraries. We demonstrate that all the expected components of a simple library are present in the mixture. The number of components in such libraries, the molar ratio of peptides as well as the possibilities of screening are discussed.
Sebestyén
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F
Department of Organic Chemistry, Eŏtvös Loránd University, Budapest, Hungary.
Szalatnyai
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T
Durgo
J A
JA
Furka
A
A
D000595:Amino Acid Sequence; D008722:Methods; D008969:Molecular Sequence Data; D010449:Peptide Mapping; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry / Q000302:isolation & purification
D010455:Peptides