title: Time to earliest peak serum antibody response to influenza vaccine in the elderly.
abstract: The earliest time at which serum antibody levels peak following administration of an influenza virus vaccine in elderly persons is not clearly defined. We compared the time intervals of 1 and 2 weeks after vaccination. A commercial trivalent vaccine containing the hemagglutinins of influenza viruses A/Texas/36/91 (H1N1), A/Johannesburg/33/94 (H3N2), and B/Harbin/7/94 was used. The hemagglutination inhibition (HAI) antibody titers at 1 week after vaccination were significantly lower than the HAI titers at 2 weeks postvaccination for all three vaccine components.
authors.affiliation: Department of Internal Medicine, Hackensack University Medical Center, New Jersey 07601, USA.
authors.forename: P A
authors.initials: PA
authors.lastname: Gross
authors.forename: C
authors.initials: C
authors.lastname: Russo
authors.forename: S
authors.initials: S
authors.lastname: Dran
authors.forename: P
authors.initials: P
authors.lastname: Cataruozolo
authors.forename: G
authors.initials: G
authors.lastname: Munk
authors.forename: S C
authors.initials: SC
authors.lastname: Lancey
mesh_terms: D000368:Aged; D000914:Antibodies, Viral / Q000097:blood*; D005260:Female; D006801:Humans; D007252:Influenza Vaccines / Q000276:immunology*; D008297:Male; D013997:Time Factors
chemical_list: D000914:Antibodies, Viral; D007252:Influenza Vaccines