title: Pharmacology of therapeutic oligonucleotides.
authors.affiliation: Department of Pharmacology and Toxicology University of Alabama at Birmingham 35294, USA.
authors.forename: R B
authors.initials: RB
authors.lastname: Diasio
authors.forename: R
authors.initials: R
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001692:Biological Transport; D002986:Clinical Trials as Topic; D015195:Drug Design; D004353:Drug Evaluation, Preclinical; D006801:Humans; D051379:Mice; D016376:Oligonucleotides, Antisense / Q000737:chemistry / Q000493:pharmacokinetics* / Q000627:therapeutic use / Q000633:toxicity; D011485:Protein Binding; D012333:RNA, Messenger / Q000037:antagonists & inhibitors; D051381:Rats; D013329:Structure-Activity Relationship; D013873:Thionucleotides / Q000493:pharmacokinetics / Q000627:therapeutic use / Q000633:toxicity
chemical_list: D016376:Oligonucleotides, Antisense; D012333:RNA, Messenger; D013873:Thionucleotides