Radiotherapy of incompletely resected, moderately differentiated mast cell tumors in the dog: 37 cases (1989-1993).
Thirty-seven dogs with moderately differentiated, cutaneous mast cell tumors had incomplete surgical excisions as determined by histopathology, but no gross evidence of tumor. All dogs were irradiated to a total dose of between 46.2 and 48.0 Gy using either an orthovoltage source (n = 20) or a linear accelerator (megavoltage) (n = 17). Radiation was delivered to an area bordered by margins of 3 cm or greater around the surgical scar. The mast cell tumors had not recurred in 97% of dogs by one year after radiation therapy and had not recurred in 93% of dogs by three years after radiation. Both orthovoltage and megavoltage radiation provide excellent local control of moderately differentiated mast cell tumors in dogs.
Frimberger
A E
AE
Department of Small Animal Medicine, Tufts University School of Veterinary Medicine, North Grafton, Massachusetts 01536, USA.
Moore
A S
AS
LaRue
S M
SM
Gliatto
J M
JM
Bengtson
A E
AE
D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D062109:Dermatologic Surgical Procedures; D004283:Dog Diseases / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D004285:Dogs; D004307:Dose-Response Relationship, Radiation; D005260:Female; D008297:Male; D012515:Mast-Cell Sarcoma / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects / Q000662:veterinary; D012867:Skin / Q000473:pathology / Q000528:radiation effects; D012878:Skin Neoplasms / Q000532:radiotherapy / Q000601:surgery / Q000662:veterinary*