title: Double line scan diffusion imaging.
abstract: A new double line scan diffusion imaging sequence (DLSDI) is presented. In DLSDI, two lines from two separate slices are acquired in each shot. As its predecessor, LSDI, DLSDI is insensitive to motion artifacts and it can be used on conventional MR scanners. In addition, DLSDI is almost twice as fast as LSDI. Preliminary results from phantom and patient studies show excellent agreement between ADC trace maps obtained with DLSDI and LSDI. The technical and the theoretical aspects of DLSDI are studied, and it is shown how the conditional random walk model can be used as an analytical tool to derive the diffusion sensitivity in the DLSDI sequence.
authors.affiliation: Brigham and Women's Hospital, Harvard Medical School, Department of Radiology, Boston, MA, USA.
authors.forename: H
authors.initials: H
authors.lastname: Gudbjartsson
authors.forename: S E
authors.initials: SE
authors.lastname: Maier
authors.forename: F A
authors.initials: FA
authors.lastname: Jolesz
mesh_terms: D001921:Brain / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000175:diagnosis; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D019047:Phantoms, Imaging; D015203:Reproducibility of Results