title: Magnesium toxicosis in two horses.
abstract: Magnesium sulfate, a saline laxative, is often used for treatment of intestinal impactions in horses. Clinical signs of hypermagnesemia are an uncommon complication following oral administration of magnesium sulfate. Overdose of magnesium sulfate in combination with renal insufficiency, hypocalcemia, or compromise of intestinal integrity may predispose horses to magnesium toxicosis. Establishment of diuresis with fluids and IV administration of calcium may provide successful treatment of magnesium toxicosis in horses.
authors.affiliation: Penn Paddock Equine Center, Annville, PA 17003, USA.
authors.forename: R W
authors.initials: RW
authors.lastname: Henninger
authors.forename: J
authors.initials: J
authors.lastname: Horst
mesh_terms: D000818:Animals; D002125:Calcium Gluconate / Q000008:administration & dosage / Q000627:therapeutic use; D002400:Cathartics / Q000506:poisoning* / Q000627:therapeutic use; D062787:Drug Overdose / Q000188:drug therapy / Q000662:veterinary; D005244:Fecal Impaction / Q000188:drug therapy / Q000662:veterinary*; D005260:Female; D006734:Horse Diseases / Q000139:chemically induced* / Q000188:drug therapy; D006736:Horses; D007262:Infusions, Intravenous / Q000662:veterinary; D008274:Magnesium / Q000097:blood; D008278:Magnesium Sulfate / Q000506:poisoning* / Q000627:therapeutic use; D008297:Male
chemical_list: D002400:Cathartics; D008278:Magnesium Sulfate; D008274:Magnesium; D002125:Calcium Gluconate