title: [The usefulness of fibrin glue spraying combined with CDDP for lung cancer].
abstract: The local slow release of an anticancer agent by one route is a form of treatment. There have been numerous reports to date that this approach might be a promising adjuvant for systemic therapy. We investigated the spraying of the operative field at a local site with cisplatin, which is considered the most effective carcinostatic in the field of lung cancer, and reported it in clinical cases selected in applying a Pilot-Study. The feature of this method is to use fibrin to spray drugs uniformly over a wide field. We expect it will be an adjuvant for postoperative purification and other uses.
authors.affiliation: Dept. of Thoracic Surgery, Dokkyo University School of Medicine.
authors.forename: H
authors.initials: H
authors.lastname: Ishihama
authors.forename: S
authors.initials: S
authors.lastname: Nagai
authors.forename: H
authors.initials: H
authors.lastname: Umezu
authors.forename: Y
authors.initials: Y
authors.lastname: Ikeda
authors.forename: K
authors.initials: K
authors.lastname: Sugita
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: M
authors.initials: M
authors.lastname: Chimoto
authors.forename: K
authors.initials: K
authors.lastname: Shimada
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000601:surgery; D000328:Adult; D000336:Aerosols; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D016190:Carboplatin / Q000008:administration & dosage; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000601:surgery; D002945:Cisplatin / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage; D006801:Humans; D007430:Intraoperative Care; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009330:Nebulizers and Vaporizers; D014751:Vindesine / Q000008:administration & dosage
chemical_list: D000336:Aerosols; D015718:Fibrin Tissue Adhesive; D016190:Carboplatin; D002945:Cisplatin; D014751:Vindesine