title: Nonocclusive excimer laser-assisted end-to-side anastomosis.
abstract: BACKGROUND
  High-flow extraintracranial bypass operation on the brain is a risky procedure because of the temporary occlusion of the intracranial portion of the internal carotid artery. We therefore developed a nonocclusive anastomosis technique in the experimental animal laboratory in 100 chronic and acute experiments in rabbits.
  
  
  METHODS
  In 40 patients we interposed a venous transplant between the external carotid artery or one of its branches and the intracranial portion of the internal carotid artery. During the construction of the distal anastomosis the recipient artery was not occluded. The donor vessel was stitched to the exterior of the recipient vessel and an Excimer laser catheter (Medolas GmbH, Amberg, Germany) was introduced by way of an artificial side branch. The tip of the laser catheter created a hole in the wall of the recipient artery just inside the anastomosis. The cut-out full-thickness portion of recipient vessel wall remained attached to the tip of the laser catheter by way of high vacuum suction and was removed together with the laser catheter. The artificial side branch was occluded with a hemostatic clip. No interruption of blood flow in the recipient artery was induced during the making of the anastomosis.
  
  
  RESULTS
  The procedure was well tolerated by the patients and a high patency rate was observed.
  
  
  CONCLUSIONS
  The nonocclusive Excimer laser-assisted anastomosis technique is safe and yields a high long-term patency rate in neurosurgical patients. It cannot be excluded that there are indications for this method in coronary bypass surgery.
authors.affiliation: Department of Neurosurgery, Medical Laser Center, University Hospital, Utrecht, the Netherlands.
authors.forename: C A
authors.initials: CA
authors.lastname: Tulleken
authors.forename: R M
authors.initials: RM
authors.lastname: Verdaasdonk
authors.forename: H J
authors.initials: HJ
authors.lastname: Mansvelt Beck
mesh_terms: D000714:Anastomosis, Surgical / Q000295:instrumentation / Q000379:methods; D000818:Animals; D001012:Aorta, Abdominal / Q000601:surgery; D002339:Carotid Arteries / Q000601:surgery; D002548:Cerebral Revascularization / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D053685:Laser Therapy; D011817:Rabbits