title: Congenital abnormalities in twins: selective termination.
abstract: Selective termination for an anomalous twin in discordant twin pregnancy has been a management option for nearly two decades. Using current conventional prenatal diagnostic techniques, the diagnosis of a twin gestation discordant for a congenital anomaly is commonly confirmed in the second trimester. Selective termination is thus usually a second-trimester procedure. The risks of second-trimester terminations as well as protocol choices, including indications and timing, have evolved over the years. Ethical issues regarding selective termination have developed significantly and continue to be debated.
authors.affiliation: Department of Obetetrics and Gynecology, Hutzel Hospital, Wayne State University, Detroit, Michigan, USA.
authors.forename: K S
authors.initials: KS
authors.lastname: Stewart
authors.forename: M P
authors.initials: MP
authors.lastname: Johnson
authors.forename: R A
authors.initials: RA
authors.lastname: Quintero
authors.forename: M I
authors.initials: MI
authors.lastname: Evans
mesh_terms: D000013:Congenital Abnormalities / Q000175:diagnosis*; D004200:Diseases in Twins / Q000175:diagnosis*; D004989:Ethics; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis*; D006801:Humans; D011247:Pregnancy; D018607:Pregnancy Reduction, Multifetal; D011262:Pregnancy Trimester, Second; D011296:Prenatal Diagnosis / Q000379:methods*; D014427:Twins