title: Differential glutamate immunoreactivity in glial cells of the retino-recipient layer of the viper optic tectum following retinal ablation. A quantitative EM immunogold study.
abstract: In normal conditions, retino-tectal terminals are densely glutamate-immunoreactive. During the degenerative process of these terminals, a significant increase of glutamate immunoreactivity has been exclusively observed in microglial cells. It is suggested that this phenomenon is consecutive to the synthesis of glutamate by these cells after their activation by degenerating optic terminals.
authors.affiliation: INSERM U-106, Hôpital de la Salpêtrière, Bâtiment de Pédiatrie, Paris, France.
authors.forename: J
authors.initials: J
authors.lastname: Repérant
authors.forename: J P
authors.initials: JP
authors.lastname: Rio
authors.forename: M
authors.initials: M
authors.lastname: Wasowicz
authors.forename: R
authors.initials: R
authors.lastname: Ward
authors.forename: D
authors.initials: D
authors.lastname: Miceli
mesh_terms: D000818:Animals; D001369:Axons / Q000502:physiology; D003714:Denervation; D005260:Female; D018698:Glutamic Acid / Q000032:analysis / Q000276:immunology*; D007150:Immunohistochemistry; D008297:Male; D016253:Microscopy, Immunoelectron; D009410:Nerve Degeneration / Q000502:physiology; D009457:Neuroglia / Q000737:chemistry* / Q000648:ultrastructure; D017729:Presynaptic Terminals / Q000737:chemistry / Q000648:ultrastructure; D012160:Retina / Q000166:cytology / Q000601:surgery; D013477:Superior Colliculi / Q000166:cytology*; D017819:Viperidae
chemical_list: D018698:Glutamic Acid