title: Assessment of malnutrition parameters in head and neck cancer and their relation to postoperative complications.
abstract: BACKGROUND
  Malnutrition is reported frequently in head and neck cancer patients. The impact of malnutrition on surgical outcome is not clearly understood. The purpose of this study was to define the usefulness of six different parameters in scoring malnutrition and to determine the nutritional parameter primarily related to postoperative complications.
  
  
  METHODS
  Sixty-four patients undergoing major surgery for advanced head and neck cancer were studied prospectively, and six different parameters were used to define malnutrition. Logistic regression was used to relate nutritional parameters to postoperative complications.
  
  
  RESULTS
  The parameters applied all identified different aspects of the nutritional status, as malnutrition varied between 20% and 67%. Logistic regression analysis identified a weight loss of more than 10% to be the most prominent predictive parameter for the occurrence of major postoperative complications.
  
  
  CONCLUSIONS
  Patients with weight loss more than 10% during the six months before surgery are at a great risk for the occurrence of major postoperative complications.
authors.affiliation: Department of Dietetics, Free University Hospital, Amsterdam, The Netherlands.
authors.forename: M A
authors.initials: MA
authors.lastname: van Bokhorst-de van der Schueren
authors.forename: P A
authors.initials: PA
authors.lastname: van Leeuwen
authors.forename: H P
authors.initials: HP
authors.lastname: Sauerwein
authors.forename: D J
authors.initials: DJ
authors.lastname: Kuik
authors.forename: G B
authors.initials: GB
authors.lastname: Snow
authors.forename: J J
authors.initials: JJ
authors.lastname: Quak
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000601:surgery*; D003679:Deglutition; D005260:Female; D006801:Humans; D007013:Hypopharynx; D007822:Laryngeal Neoplasms / Q000150:complications* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000150:complications* / Q000601:surgery*; D009748:Nutrition Disorders / Q000209:etiology*; D009752:Nutritional Status; D009960:Oropharynx; D010610:Pharyngeal Neoplasms / Q000601:surgery*; D011183:Postoperative Complications; D011446:Prospective Studies; D012044:Regression Analysis; D012307:Risk Factors; D015431:Weight Loss