Body composition analysis by dual energy X-ray absorptiometry in female diabetics differ between manufacturers.
OBJECTIVE
Comparison of body composition results by two dual energy X-ray absorptiometry (DXA) instruments, namely QDR-2000 from Hologic Inc and from Lunar in subpopulations of lean and obese subjects.


METHODS
Cross-sectional study with 85 female diabetics (BMI 18-43 kg/m2) measured with both DXA instruments.


RESULTS
The regression lines for fat tissue mass (FTM), FAT% and total body bone mineral content (TBMC), but not lean tissue mass (LTM), were different from the line of identity (P < 0.01). However, the relationships were high (r2 > 0.95), and the corresponding SEE%'s were low (0.8-4.8%), and were independent of BMI. FTM and FAT% measured by the QDR-2000 were 10% higher, and LTM and TBMC 6% lower, than by DPX (P < 0.001).


CONCLUSIONS
There were lack of agreements between total body composition results by DPX Lunar, and QDR-2000 Hologic Inc. Individual results on the two systems cannot be directly compared. Standardization of body composition measurements by DXA is strongly needed.
Kistorp
C N
CN
Center for Clinical and Basic Research, Ballerup, Denmark.
Svendsen
O L
OL
D015502:Absorptiometry, Photon / Q000295:instrumentation; D000293:Adolescent; D000368:Aged; D001823:Body Composition; D015519:Bone Density; D003430:Cross-Sectional Studies; D003922:Diabetes Mellitus, Type 1; D003924:Diabetes Mellitus, Type 2; D005260:Female; D006801:Humans; D008875:Middle Aged; D015203:Reproducibility of Results