title: Dosimetric analysis and clinical implementation of 6 MV X-ray radiosurgery beam.
abstract: The dosimetric data on tissue maximum ratios (TMR), output factors, off axis ratios and beam profiles are presented for small circular fields of diameters ranging from 12.5 to 40 mm for 6 MV radiosurgery beam. It is noticed that dmax increases as the collimator field size increases. Comparison of our data with the published TMR and output factors of similar small circular fields shows that our values are higher than those data. Similarities in trend are noticed with the published isodose volumes for 1-5 and 10 arcs. Not much variation is seen beyond two arcs for 80% isodose volumes for all the field sizes. The variation is small in 20% isodose volumes beyond three arcs. Variations are noticed in 5% isodose volumes for 12.5 mm diameter collimated beam. Our experience has been exclusively with malignant neoplasms. An ideal target volume is covered by 80% isodose volume with 3-4 arcs and a single isocenter. Sixteen patients have been treated to date at our institution, including one patient with brain metastases, two patients with meningiomas, one patient with lymphoma and 12 patients with astrocytomas. The majority of tumors have been treated with single isocenter but some as large as 7 cm have been treated safely with two isocenters.
authors.affiliation: Evanston Hospital Corporation, Division of Medical Physics, Northwestern University Medical School, IL 60201, USA.
authors.forename: S G
authors.initials: SG
authors.lastname: Prasad
authors.forename: K
authors.initials: K
authors.lastname: Parthasaradhi
authors.forename: C
authors.initials: C
authors.lastname: Des Rosiers
authors.forename: W D
authors.initials: WD
authors.lastname: Bloomer
authors.forename: M A
authors.initials: MA
authors.lastname: LaCombe
mesh_terms: D001932:Brain Neoplasms / Q000532:radiotherapy / Q000601:surgery; D006801:Humans; D009369:Neoplasms / Q000532:radiotherapy; D016634:Radiosurgery; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy