Skeletal metastases from soft-tissue sarcomas. Incidence, patterns, and radiological features.
We reviewed 277 patients with soft-tissue sarcoma (STS) treated between 1975 and 1995 to study the incidence, distribution, time of appearance, and radiological findings of skeletal metastases. Of these, 28 (10.1%) had metastases within a mean period of 18.6 months after admission. The incidence of skeletal metastases differed among the histological subtypes of sarcoma; alveolar soft-part sarcoma, dedifferentiated liposarcoma, angiosarcoma, and rhabdomyosarcoma tended to show higher incidences. The regional bones close to the primary tumour were affected in 13 (46.4%) of the 28 patients, and the axial bones in 18 (64.3%). Radiologically, the metastatic bony lesions predominantly showed osteolytic changes, and there were pathological fractures in 21 of 44 lesions.
Yoshikawa
H
H
Department of Orthopaedic Surgery, Osaka Medical Centre for Cancer and Cardiovascular Diseases and Osaka University Medical School, Japan.
Ueda
T
T
Mori
S
S
Araki
N
N
Kuratsu
S
S
Uchida
A
A
Ochi
T
T
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001859:Bone Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000556:secondary*; D002648:Child; D005260:Female; D005598:Fractures, Spontaneous / Q000150:complications; D018219:Histiocytoma, Benign Fibrous / Q000150:complications / Q000556:secondary; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D012208:Rhabdomyosarcoma / Q000150:complications / Q000556:secondary; D012509:Sarcoma / Q000150:complications / Q000000981:diagnostic imaging / Q000556:secondary*; D012983:Soft Tissue Neoplasms / Q000150:complications / Q000473:pathology*