title: Allele frequencies for 20 microsatellites in a worldwide population survey.
abstract: 20 microsatellite polymorphisms: HUMHPRT, HUMD3S1358, HUMTH01, HUMACPP, HUMVWF, HUMD16S310, HUMD4S243, HUMTPO, HUMFES/FPS, HUMF13A1, HUMDHFRP2, HUMD11S2010, HUMD13S767, HUMD9S926, HUMD2S1328, HUMD14S306, HUMD18S848, HUMD5S818, HUMD7S820 and HUMFGA were analyzed in a worldwide survey covering five continents and allele frequencies are given. There is a high heterogeneity in allele frequencies among continents. A neighbor-joining tree based on Fst distance shows a pattern of differentiation that may reflect the role of drift in the development of genetic differences among humans. The variation found between continents confirms the usefulness of tetranucleotide microsatellites in human genetic variation studies.
authors.affiliation: Laboratori d'Antropologia, Facultat de Biologia, Universitat de Barcelona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Pérez-Lezaun
authors.forename: F
authors.initials: F
authors.lastname: Calafell
authors.forename: E
authors.initials: E
authors.lastname: Mateu
authors.forename: D
authors.initials: D
authors.lastname: Comas
authors.forename: E
authors.initials: E
authors.lastname: Bosch
authors.forename: J
authors.initials: J
authors.lastname: Bertranpetit
mesh_terms: D000483:Alleles; D005787:Gene Frequency; D014644:Genetic Variation; D005828:Genetics, Population; D006801:Humans; D018895:Microsatellite Repeats; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic