[Latent long QT syndrome: discription of a clinical case].
Latent forms of long QT syndrome have been already reported. We describe one case of a 27 years old female patient who experienced an episode of cardiac arrest after several puffs of salbutamole. The malignant arrhythmia causing the cardiac arrest was torsade de pointes degenerated into ventricular fibrillation. The patient ECG showed a normal QTc basal interval and the correct diagnosis was made by contemporary recording of the ECG and MAP during orciprenalina infusion. After drug infusion, we have recorded a MAP lengthening and a dispersion of MAP duration between the right ventricular apex and the right ventricular outflow tract. These modifications were concomitant with the appearance of "humps" (probably related to the presence of early afterdepolarizations), a QT interval lengthening and morphologic changes of the T and U waves.
Castro
A
A
Dipartimento Malattie del Cuore, Ospedale-Azienda S. Filippo Neri, Roma.
Pandozi
C
C
Bianconi
L
L
Toscano
S
S
Santini
M
M
D000280:Administration, Inhalation; D000318:Adrenergic beta-Agonists / Q000008:administration & dosage / Q000009:adverse effects / Q000494:pharmacology / Q000627:therapeutic use; D000328:Adult; D000420:Albuterol / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D001249:Asthma / Q000150:complications / Q000188:drug therapy; D004562:Electrocardiography; D005260:Female; D006323:Heart Arrest / Q000139:chemically induced / Q000503:physiopathology; D006801:Humans; D008133:Long QT Syndrome / Q000473:pathology / Q000503:physiopathology*; D009921:Metaproterenol / Q000494:pharmacology
D000318:Adrenergic beta-Agonists; D009921:Metaproterenol; D000420:Albuterol
Sindrome del QT lungo latente: descrizione di un caso clinico.