title: Small cell carcinoma of the prostate: a case report.
abstract: A case of small cell carcinoma of the prostate without a primary lesion in the lung was reported. The cancer was diagnosed after the patient complained of lumbago caused by bone metastasis. The tumor was 5.9 x 5.0 x 4.6 cm. The patient was treated with 4 courses of chemotherapy using cisplatin and etoposide. The tumor diminished to 4.0 x 4.0 x 3.5 cm after completion of the 4 courses of treatment. Prostatic antigen levels were less than 1.0 ng/mL during the therapy. Neuron-specific enolase levels were 35.9 ng/mL at the beginning of therapy, and decreased to 7.4 ng/mL after completion of 4 courses of treatment. The patient died 3 months after the completion of treatment. This regimen had some value for inhibiting the growth of small cell carcinoma.
authors.affiliation: Department of Urology, Yokohama City Kowan Hospital, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Sano
authors.forename: K
authors.initials: K
authors.lastname: Miyai
authors.forename: S
authors.initials: S
authors.lastname: Yoshida
mesh_terms: D001707:Biopsy, Needle; D018288:Carcinoma, Small Cell / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D011471:Prostatic Neoplasms / Q000473:pathology / Q000556:secondary* / Q000628:therapy