title: A high-speed gated baseline restorer and its implementation in a blood cell volume analyser.
abstract: Accurate measurement of the height of individual pulses in a signal that is a.c.-coupled is dependent upon correcting a changing baseline to a constant value. A new fast baseline restorer, using internally triggered gated feedback with gain, has been designed and a version optimized for Gaussian-shaped pulses. Performance is dependent on the magnitudes of both the forward and the feedback gains. The design presented can achieve a 0.5% accuracy in pulse height for a minimum pulse width of 2.5 microseconds or for 5 microseconds overlapping pulses as long as the overlap is less than 50%. Typical applications for the baseline restorer include blood cell volume measurement systems, scintillation counters and radiation spectroscopy.
authors.affiliation: School of Biomedical Engineering, University of Dundee, UK.
authors.forename: E W
authors.initials: EW
authors.lastname: Abel
authors.forename: S
authors.initials: S
authors.lastname: Inglis
authors.forename: Y
authors.initials: Y
authors.lastname: Liu
authors.forename: J J
authors.initials: JJ
authors.lastname: Belch
authors.forename: A
authors.initials: A
authors.lastname: Koop
mesh_terms: D001698:Biomedical Engineering; D001773:Blood Cells / Q000166:cytology*; D048429:Cell Size; D004582:Electronics, Medical; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D005246:Feedback; D005434:Flow Cytometry / Q000295:instrumentation*; D006801:Humans