title: New approach to surgical management of early esophageal thoracic perforation: primary suture repair reinforced with absorbable mesh and fibrin glue.
abstract: Esophageal perforation is a life-threatening situation and represents a major therapeutic challenge. Results have improved in recent years particularly as a result of progress in antibiotic therapy and the use of total parenteral nutrition. Surgical management retains a predominant role, involving early primary closure and thoracic drainage. We have made an addition to the surgical management by applying an absorbable mesh and fibrin glue to the repaired site. Seven patients (ages 38-79 years) were treated as described. The mean interval from leak to surgery was 28 hours. Six patients had an uneventful postoperative course with a mean hospital stay of 34 days (range 26-45 days). In one case the technique failed and the patient required an exclusion-diversion procedure. All 7 patients recovered without mortality. We believe that this technique provides a real improvement for this precarious esophageal repair.
authors.affiliation: Department of Surgery, Hôpital Pontchaillou, University of Rennes, Rennes, France.
authors.forename: E
authors.initials: E
authors.lastname: Bardaxoglou
authors.forename: D
authors.initials: D
authors.lastname: Manganas
authors.forename: B
authors.initials: B
authors.lastname: Meunier
authors.forename: S
authors.initials: S
authors.lastname: Landen
authors.forename: G J
authors.initials: GJ
authors.lastname: Maddern
authors.forename: J P
authors.initials: JP
authors.lastname: Campion
authors.forename: B
authors.initials: B
authors.lastname: Launois
mesh_terms: D000328:Adult; D000368:Aged; D004939:Esophageal Perforation / Q000601:surgery*; D005260:Female; D015718:Fibrin Tissue Adhesive; D006801:Humans; D008297:Male; D008875:Middle Aged; D013526:Surgical Mesh; D013536:Suture Techniques
chemical_list: D015718:Fibrin Tissue Adhesive