title: Effects of repeated hyperthermal stress on blood cells in vivo.
abstract: The effects of repeated hyperthermal stress on blood cells were examined in seven healthy subjects who took three 3-minute 47 degrees C hotspring baths daily for three consecutive weeks. After a 3-minute 47 degrees C bath, the sublingual temperature was transiently increased about 1.8 degrees C, returning to the baseline level within 60 min. Two weeks after completing the 3-week bathing period, monocytes were increased and eosinophils were decreased significantly. Total lymphocytes and CD3+ cells tended to be decreased. Interestingly, CD4+ cells were decreased significantly at the time of completing the 3-week bathing period and returned to the baseline level two weeks later. These findings suggest that repeated hyperthermal stress may induce alteration of the blood cells.
authors.affiliation: Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kubota
authors.forename: H
authors.initials: H
authors.lastname: Kurabayashi
authors.forename: H
authors.initials: H
authors.lastname: Take
authors.forename: K
authors.initials: K
authors.lastname: Tamura
authors.forename: T
authors.initials: T
authors.lastname: Shirakura
mesh_terms: D000328:Adult; D000368:Aged; D001494:Baths / Q000009:adverse effects; D001772:Blood Cell Count; D001773:Blood Cells; D017252:CD3 Complex / Q000378:metabolism; D018791:CD4 Lymphocyte Count; D004804:Eosinophils; D005260:Female; D006358:Hot Temperature / Q000009:adverse effects*; D006801:Humans; D018655:Lymphocyte Count; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009000:Monocytes; D013312:Stress, Physiological / Q000097:blood*; D013997:Time Factors
chemical_list: D017252:CD3 Complex