title: The prevalence and consequences of missed abortion in twin pregnancies at 10 to 14 weeks of gestation.
abstract: In singleton pregnancies at 10 to 14 weeks of gestation the prevalence of missed abortion is about 2%. In an ultrasound screening study at 10 to 14 weeks of gestation involving 492 twin pregnancies the prevalence of missed abortion was about twice as high as in singletons. The risk of subsequent miscarriage in twin pregnancies with one missed abortion was about ten times higher than in normal twin pregnancies. These findings may have important implications both in terms of counselling and for future research into the causes of miscarriage.
authors.affiliation: Harris Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, London, UK.
authors.forename: N J
authors.initials: NJ
authors.lastname: Sebire
authors.forename: S
authors.initials: S
authors.lastname: Thornton
authors.forename: K
authors.initials: K
authors.lastname: Hughes
authors.forename: R J
authors.initials: RJ
authors.lastname: Snijders
authors.forename: K H
authors.initials: KH
authors.lastname: Nicolaides
mesh_terms: D000030:Abortion, Missed / Q000453:epidemiology*; D000328:Adult; D004739:England / Q000453:epidemiology; D005260:Female; D005313:Fetal Death; D005865:Gestational Age; D006801:Humans; D008423:Maternal Age; D011247:Pregnancy; D011256:Pregnancy Outcome; D011261:Pregnancy Trimester, First; D011272:Pregnancy, Multiple / Q000706:statistics & numerical data*; D015995:Prevalence; D014429:Twins, Dizygotic / Q000706:statistics & numerical data; D014430:Twins, Monozygotic / Q000706:statistics & numerical data