Assessing quality of life in comparative cancer clinical trials: does it make a difference?
Many randomized Phase III trials of cancer therapy involve quality of life assessments. This paper argues for graphical presentation of quality of life measures in order to visualize changes over time.
Machin
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Medical Research Council Cancer Trials Office, Cambridge, United Kingdom.
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects; D017326:Clinical Trials, Phase III as Topic; D006801:Humans; D008137:Longitudinal Studies; D009369:Neoplasms / Q000188:drug therapy* / Q000401:mortality; D011788:Quality of Life; D016032:Randomized Controlled Trials as Topic; D016019:Survival Analysis