title: Effect of inadequate cardiac output reserve on exercise tolerance in patients with moderate mitral stenosis.
abstract: Twenty-nine patients with moderate mitral stenosis and 29 age-matched normal controls underwent symptom-limited upright bicycle exercise testing with simultaneous hemodynamic monitoring. Exercise tolerance in the mitral stenosis group was found to be limited by inadequate cardiac output reserve and not by resting mitral valve area or exercise pulmonary capillary wedge pressure.
authors.affiliation: Duke University Medical Center, Department of Medicine, Durham, North Carolina 27710, USA.
authors.forename: V H
authors.initials: VH
authors.lastname: Rigolin
authors.forename: M B
authors.initials: MB
authors.lastname: Higgenbotham
authors.forename: P A
authors.initials: PA
authors.lastname: Robiolio
authors.forename: S E
authors.initials: SE
authors.lastname: Hearne
authors.forename: W A
authors.initials: WA
authors.lastname: Baker
authors.forename: K B
authors.initials: KB
authors.lastname: Kisslo
authors.forename: J K
authors.initials: JK
authors.lastname: Harrison
authors.forename: T M
authors.initials: TM
authors.lastname: Bashore
mesh_terms: D000328:Adult; D000368:Aged; D002302:Cardiac Output; D016022:Case-Control Studies; D005080:Exercise Test; D017079:Exercise Tolerance; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000503:physiopathology*; D012044:Regression Analysis