title: Betaxolol-associated hyperpigmentation of the fingers in a patient with unrelated contact dermatitis.
abstract: Betaxolol ophthalmic solution has been associated with periocular skin hyperpigmentation. We report a case of a woman with hyperpigmentation of the fingers associated with oral betaxolol. Based on case reports associated with the topical ophthalmic product, we believe the hyperpigmentation was likely caused by oral betaxolol.
authors.affiliation: Division of Dermatology, Pennsylvania State University, College of Medicine, Hershey 17033, USA.
authors.forename: D R
authors.initials: DR
authors.lastname: Adams
authors.forename: J G
authors.initials: JG
authors.lastname: Marks
mesh_terms: D000284:Administration, Oral; D000485:Allergens / Q000009:adverse effects; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D015784:Betaxolol / Q000008:administration & dosage / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000209:etiology*; D005260:Female; D005385:Fingers; D006027:Glycosides / Q000009:adverse effects; D006229:Hand Dermatoses / Q000139:chemically induced* / Q000209:etiology; D006801:Humans; D017495:Hyperpigmentation / Q000139:chemically induced*; D008875:Middle Aged; D010944:Plants; D012978:Sodium Oxybate / Q000009:adverse effects / Q000031:analogs & derivatives
chemical_list: D000485:Allergens; D000959:Antihypertensive Agents; D006027:Glycosides; C062516:tuliposide A; D012978:Sodium Oxybate; D015784:Betaxolol