Immunology of hematopoietic stem cell transplantation: a brief review of its history.
The history of clinical marrow transplantation since 1968 is reviewed with an emphasis on immunological and immunogenetic aspects. The events leading to the creation of an international network of volunteer donor registries and the implementation of unrelated allogeneic marrow transplantation as a routine procedure are discussed. Current major issues which need to be resolved are addressed in order to set the stage for the topics covered in this volume of Immunological Reviews.
Dupont
B
B
Sloan-Kettering Institute for Cancer Research, Memorial Sloan-Kettering Cancer Center, New York 10021, USA. b-dupont@ski.mskcc.org
D000818:Animals; D018380:Hematopoietic Stem Cell Transplantation / Q000266:history*; D049673:History, 20th Century; D006801:Humans; D014181:Transplantation Immunology