title: [Malignant anorectal melanoma: description of a clinical case and review of the literature].
abstract: Malignant ano-rectal melanoma is a rare pathology without characteristic symptoms. It is more frequent in females than in males (ratio 2:1) and represents 3-15% of anal canal tumours. A case of a woman who recently came to us complaining of painful defecation, tenesmus and rectal bleeding induced us to reconsider the diagnostic and therapeutic implications in ano-rectal melanoma. The low incidence of cases reported and the negative 5-year prognosis are due to late, often incidental, diagnosis during clinical observation for hemorrhoids, rectal polyps or rhagades, together with the aspecificity of the tumour symptoms. We hope our case report emphasizes the importance of conducting early diagnosis in patients at risk of ano-rectal melanoma.
authors.affiliation: Département de médecine interne et de gériatrie, Université des études de Catania, Italie.
authors.forename: M
authors.initials: M
authors.lastname: Malaguarnera
authors.forename: G
authors.initials: G
authors.lastname: Pistone
authors.forename: L
authors.initials: L
authors.lastname: Succi
authors.forename: T
authors.initials: T
authors.lastname: Pontillo
authors.forename: A
authors.initials: A
authors.lastname: Laurino
authors.forename: D
authors.initials: D
authors.lastname: Russello
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001005:Anus Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008545:Melanoma / Q000175:diagnosis* / Q000628:therapy*; D008875:Middle Aged; D009367:Neoplasm Staging; D011379:Prognosis; D011879:Radiotherapy Dosage; D012004:Rectal Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D016019:Survival Analysis; D016896:Treatment Outcome
vernacular_title: Mélanome malin ano-rectal: description d'un cas clinique et revue de la littérature.