Increased recognition of IgA nephropathy in African-American children.
Based upon the percentage of cases of IgA nephropathy (IgAN) in biopsy series, a lower prevalence has been assumed for African-Americans compared with Americans of European descent. This may be due to a racial difference in the basic underlying pathology of IgAN or to racial differences in patterns of referral and biopsy selection practices. Over the past decade (1985-1994), we have found similar incidences of IgAN in Caucasian and African-American children from Shelby County, Tennessee. The incidence was 3.0 cases per million per year for Caucasian and 5.7 cases per million per year for African-American children. IgAN may be more common in African-American children than previously appreciated. Population-based incidence studies will be necessary to determine whether or not our experience has become a more widespread phenomenon.
Sehic
A M
AM
Department of Pediatrics, University of Tennessee, Memphis 38103, USA.
Gaber
L W
LW
Roy
S
S
Miller
P M
PM
Kritchevsky
S B
SB
Wyatt
R J
RJ
D000293:Adolescent; D044383:Black People; D002648:Child; D002675:Child, Preschool; D005260:Female; D005922:Glomerulonephritis, IGA / Q000453:epidemiology / Q000208:ethnology*; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D044465:White People; D001741:Black or African American