title: [Laboratory diagnosis of lipid imbalance].
abstract: Accurate diagnosis of hyperlipidaemia is necessary for the effective treatment. Measurements in serum or plasma obtained after an overnight fast of over 16 hours should include total cholesterol, triglycerides and HDL-cholesterol concentrations; LDL-cholesterol can be calculated using the Friedelwald's formula. Lipoprotein electrophoresis is used to define different phenotypes of hyperlipoproteinaemia according to the Fredrickson's classification. More sophisticated tests include apolipoprotein analysis, determination of Lp(a) concentration, activities of enzymes involved in lipid metabolism and genetic studies. Secondary causes of hyperlipidaemia, including liver, kidney, endocrine disorders should be excluded using the laboratory methods.
authors.affiliation: Katedry i Zakładu Biochemii i Chemii Slaskiej Akademii Medycznej w Katowicach.
authors.forename: K
authors.initials: K
authors.lastname: Siemianowicz
mesh_terms: D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003937:Diagnosis, Differential; D004700:Endocrine System Diseases / Q000175:diagnosis; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000145:classification / Q000175:diagnosis*; D007674:Kidney Diseases / Q000175:diagnosis; D008052:Lipid Metabolism, Inborn Errors / Q000097:blood / Q000175:diagnosis; D008107:Liver Diseases / Q000175:diagnosis; D010641:Phenotype; D014280:Triglycerides / Q000097:blood
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D002784:Cholesterol
vernacular_title: Diagnostyka laboratoryjna gospodarki lipidowej.