Etiology and treatment of acquired coagulopathies in the critically ill adult and child.
Excessive bleeding frequently complicates the care of critically ill patients. Except in the case of trauma or inpatients with known coagulopathies, the bleeding is generally not directly related to the illness that results in admission to the intensive care unit. In general, the causes of the bleeding can be divided into three categories: consumptive coagulopathies, bleeding related to "hepatic issues," and iatrogenic causes. In most circumstances, the pathogenesis and management of these acquired coagulopathies do not differ between the adult and child patient. However, some differences do exist in regards to the clinical manifestations and management of some consumptive coagulopathies. This article reviews the more common causes of bleeding in the critically ill patient and outlines diagnostic and treatment approaches for these patients. Particular emphasis will be placed on the differences in presentation and management where differences exist.
Parker
R I
RI
Department of Pediatrics, State University of New York at Stony Brook, USA.
D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects; D001778:Blood Coagulation Disorders / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D002648:Child; D002675:Child, Preschool; D004211:Disseminated Intravascular Coagulation / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006801:Humans; D007223:Infant; D008107:Liver Diseases / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D065227:Transfusion Reaction; D014813:Vitamin K Deficiency / Q000175:diagnosis / Q000209:etiology / Q000628:therapy
D000925:Anticoagulants