title: Further search for virulence factors encoded by Salmonella serovar-specific plasmids.
abstract: The so called Salmonella virulence plasmids which are specifically prevalent among some of the S. enterica serovars were shown to contribute only marginally to the virulence make-up of salmonella, which is in contrast to Shigella and Yersinia spp. The experiments reported in this paper failed to find encoded plasmid factors which contribute to serum resistance, surface antigens, immunoinsufficiency or to up-regulation of chromosomally encoded factors such as toxins, surface antigens etc. Taking into consideration the rare prevalence of these plasmids among S. enterica but their common occurrence among a few of its serovars, their virulence implication remains an enigma.
authors.affiliation: Institut für Mikrobiologie und Immunologie, Medizinische Fakultät, Universität Magdeburg.
authors.forename: S
authors.initials: S
authors.lastname: Glockner
authors.forename: W
authors.initials: W
authors.lastname: Streckel
authors.forename: H
authors.initials: H
authors.lastname: Struy
authors.forename: A
authors.initials: A
authors.lastname: Fruth
authors.forename: J
authors.initials: J
authors.lastname: Morenz
authors.forename: H
authors.initials: H
authors.lastname: Tschäpe
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis / Q000235:genetics; D000942:Antigens, Bacterial / Q000032:analysis; D000954:Antigens, Surface / Q000032:analysis; D001770:Blood Bactericidal Activity; D004768:Enterotoxins / Q000096:biosynthesis / Q000235:genetics; D006801:Humans; D006877:Hydroxamic Acids / Q000378:metabolism; D051379:Mice; D008807:Mice, Inbred BALB C; D010957:Plasmids / Q000235:genetics* / Q000276:immunology / Q000378:metabolism; D012475:Salmonella / Q000235:genetics* / Q000472:pathogenicity*; D012481:Salmonella Infections, Animal / Q000276:immunology / Q000382:microbiology; D012477:Salmonella enteritidis / Q000235:genetics / Q000472:pathogenicity; D012486:Salmonella typhimurium / Q000235:genetics / Q000472:pathogenicity; D012763:Shigella flexneri / Q000235:genetics / Q000472:pathogenicity; D017262:Siderophores / Q000096:biosynthesis; D013045:Species Specificity; D014774:Virulence / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D000954:Antigens, Surface; D004768:Enterotoxins; D006877:Hydroxamic Acids; D017262:Siderophores; C082864:enterotoxin, Salmonella; C031819:aerobactin