Prevention and treatment of hemorrhagic cystitis.
Hemorrhagic cystitis is a syndrome associated with certain disease states as well as exposure to drugs, viruses, and toxins. It manifests as diffuse bleeding of the endothelial lining of the bladder. Treatment includes intravesical, systemic, and nonpharmacologic therapies, all of which have advantages and disadvantages.
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College of Pharmacy, University of Michigan, Ann Arbor 48109-0008, USA.
D000477:Alkylating Agents / Q000009:adverse effects*; D003520:Cyclophosphamide / Q000009:adverse effects*; D003556:Cystitis / Q000209:etiology / Q000517:prevention & control* / Q000628:therapy*; D006417:Hematuria / Q000517:prevention & control / Q000628:therapy; D006470:Hemorrhage / Q000209:etiology / Q000517:prevention & control* / Q000628:therapy*; D006801:Humans; D015080:Mesna / Q000627:therapeutic use; D001743:Urinary Bladder / Q000187:drug effects* / Q000473:pathology
D000477:Alkylating Agents; D003520:Cyclophosphamide; D015080:Mesna