[The characteristics of the clinical course and treatment of chronic obstructive lung diseases against a background of lymphoproliferative diseases].
The authors studied expectoration, cough clearance and immunity in 48 patients with exacerbation of chronic obstructive pulmonary affections (COPA) associated with lymphoproliferative diseases (chronic lymphoid leukemia, lymphocytic lymphoma, myeloma) versus 16 control patients suffering from COPA alone. patients of the test group received cytostatics and steroids according to standard schemes. They are shown to develop aggravation of immune defects with emergence of persistent secondary immunodeficiency, more marked disturbance of tracheobronchial clearance with more frequent occurrence of persistent ciliary dyskinesia. This resulted in slower relief of clinical symptoms, more severe course dictating the necessity of longer treatment, the addition of immunocorrectors, antibacterial drugs without immunosuppressive action.
Provotorov
V M
VM
Kazabtsov
A Iu
AIu
D000328:Adult; D000917:Antibody Formation; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007111:Immunity, Cellular; D008173:Lung Diseases, Obstructive / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D008232:Lymphoproliferative Disorders / Q000175:diagnosis* / Q000188:drug therapy / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009079:Mucociliary Clearance; D012131:Respiratory Insufficiency / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology
Osobennosti klinicheskogo techeniia i lecheniia khronicheskikh obstruktivnykh zabolevaniĭ legkikh na fone limfoproliferativnykh bolezneĭ.