title: Antiphospholipid syndrome complicated by thrombosis of the superior mesenteric artery, co-existence of smooth muscle hyperplasia.
abstract: A 37-year-old woman underwent an emergency operation at our hospital because of severe abdominal pain and ileus. Most of her small intestine and ascending colon were observed to have become necrotic due to occlusion of her superior mesenteric artery (SMA). Pathological findings of the resected intestine revealed that her SMA was completely thrombosed 2 cm distal from its origin with smooth muscle proliferation. Post-surgical blood analysis of her pre-operative serum was positive for lupus anticoagulant and antinuclear antibodies. She noticed vaginal bleeding due to missed abortion on the 31st day after the operation. We diagnosed her acute abdominal pain to be that of antiphospholipid syndrome associated with her pregnancy.
authors.affiliation: Department of Internal Medicine, Komaki City Hospital, Aichi.
authors.forename: E
authors.initials: E
authors.lastname: Kojima
authors.forename: K
authors.initials: K
authors.lastname: Naito
authors.forename: M
authors.initials: M
authors.lastname: Iwai
authors.forename: Y
authors.initials: Y
authors.lastname: Hirose
authors.forename: K
authors.initials: K
authors.lastname: Isobe
authors.forename: K
authors.initials: K
authors.lastname: Takano
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000030:Abortion, Missed / Q000209:etiology; D000022:Abortion, Spontaneous / Q000209:etiology; D000328:Adult; D016736:Antiphospholipid Syndrome / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D001327:Autoimmune Diseases / Q000097:blood / Q000150:complications* / Q000175:diagnosis / Q000276:immunology; D005260:Female; D006417:Hematuria / Q000209:etiology; D006801:Humans; D006965:Hyperplasia; D007418:Intestinal Pseudo-Obstruction / Q000209:etiology* / Q000601:surgery; D016682:Lupus Coagulation Inhibitor / Q000097:blood; D017538:Mesenteric Artery, Superior / Q000473:pathology; D009131:Muscle, Smooth, Vascular / Q000473:pathology*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis* / Q000276:immunology; D013478:Superior Mesenteric Artery Syndrome / Q000209:etiology*; D013927:Thrombosis / Q000209:etiology*
chemical_list: D016682:Lupus Coagulation Inhibitor