title: [Noninvasive ventilation in acute respiratory insufficiency].
abstract: OBJECTIVE
  Noninvasive positive pressure ventilation (NPPV) via face mask offers in comparison to endotracheal intubation in treating patients with acute respiratory failure (ARF) advantages like allowing swallowing and coughing. We report our experiences and try to verify the indications and the efficacy of NPPV.
  
  
  METHODS
  In the period of January 1991 until August 1996 109 patients (30 female, 79 male, mean age 61 +/- 12 years) received mechanical ventilation with NPPV representing 25% of all MVs in this term. As baseline capillary blood gases (CBG) were found: pH: 7.30 +/- 0, 10; pCO2: 64 +/- 19; pO2: 60 +/- 19 (all patients received supplemental oxygen). Success of NPPV was determined by an improvement of the baseline CBG.
  
  
  RESULTS
  NPPV was successful in 77 (71%) patients. Considering the kind of respiratory insufficiency the patient population was divided into 4 groups 1. acute hypoxemic respiratory failure, 2. acute hypercapnic ventilatory failure, 3. acute decompensation of chronic respiratory insufficiency (CRI) and 4. combined failure. Considering these subgroups we obtained the best results in the group of patients with hypercapnic disturbances. In patients with hypoxemic RF we observed a success of NPPV if the improvement of CBG occurred in the early stage (< or = 12 hours) of NPPV.
  
  
  CONCLUSIONS
  Our data indicate that application of NPPV is an effective and safe alternative to endotracheal intubation in many patients with hypercapnic ventilatory failure. NPPV is also successful in patients with hypoxemic RF with a milder course.
authors.affiliation: Pneumologische Klinik, Zentralkrankenhaus Gauting.
authors.forename: S
authors.initials: S
authors.lastname: Heindl
authors.forename: O
authors.initials: O
authors.lastname: Karg
authors.forename: F
authors.initials: F
authors.lastname: Bullemer
authors.forename: P
authors.initials: P
authors.lastname: Kroworsch
authors.forename: J
authors.initials: J
authors.lastname: Pahnke
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D002245:Carbon Dioxide / Q000097:blood; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D011175:Positive-Pressure Respiration / Q000295:instrumentation*; D011659:Pulmonary Gas Exchange / Q000502:physiology; D012131:Respiratory Insufficiency / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome; D014692:Ventilation-Perfusion Ratio / Q000502:physiology
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen
vernacular_title: Nichtinvasive Beatmung bei akuter respiratorischer Insuffizienz.