Comparison between the erythrocyte and urinary Sda antigen distribution in a large number of individuals from Emilia-Romagna, a region of northern Italy.
In this study we found that the frequencies of Sda antigen on erythrocytes and urine of a large number of individuals from Emilia-Romagna (a region of northern Italy) are 0.89 and 0.93, respectively. The hypothesis that the infection by pyelonephritogenic Escherichia coli strains with specific adhesins for the alpha 2,3sialyl-galactosyl structure might operate as selective agents for the high frequency of Sda antigen in distal renal cells is discussed.
Conte
R
R
Servizio di Immunoematologia e Trasfusionale, Ospedale Policlinico S. Orsola, Bologna, Italy.
Serafini-Cessi
F
F
D001789:Blood Group Antigens / Q000097:blood* / Q000652:urine*; D004912:Erythrocytes / Q000276:immunology*; D006801:Humans; D007558:Italy; D009844:Oligosaccharides / Q000097:blood* / Q000652:urine*
D001789:Blood Group Antigens; D009844:Oligosaccharides; C106678:Sd(a) determinant