title: Influence of acute smoking exposure on the subsequent reinforcing value of smoking.
abstract: The reinforcing value of smoking (i.e., the degree to which a smoker will work to obtain smoking) after varying the magnitude of prior smoke exposure in smokers not trying to quit was examined. Eight men and 8 women participated in 5 sessions involving manipulation of prior exposure to smoking: 0, 2, 6, or 12 puffs after overnight smoking abstinence or ad-lib smoking before the session. After exposure, participants engaged in a computer task involving concurrent schedules of reinforcement for smoke puffs (16% all trials) versus money (4-64%). Only the greatest amount of prior exposure (ad lib) produced a significant reduction in subsequent responding for smoke puffs. No exposure condition significantly increased responding above that for 0 puffs, indicating no priming effect. By contrast, self-report measures of desire to smoke and amount of money participants would pay for a cigarette declined sharply with greater prior exposure. These measures were correlated only weakly with smoke-reinforced responding on the behavioral task, suggesting that subjective versus behavioral measures assess different dimensions of smoking's reward value.
authors.affiliation: Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pennsylvania 15213, USA. kperkins@vms.cis.pitt.edu
authors.forename: K A
authors.initials: KA
authors.lastname: Perkins
authors.forename: J
authors.initials: J
authors.lastname: Grobe
authors.forename: C
authors.initials: C
authors.lastname: Fonte
mesh_terms: D000328:Adult; D001944:Breath Tests; D002248:Carbon Monoxide / Q000378:metabolism; D005260:Female; D006801:Humans; D008297:Male; D012008:Recurrence; D012055:Reinforcement Schedule; D012201:Reward; D012907:Smoking / Q000523:psychology*; D016540:Smoking Cessation / Q000523:psychology*
chemical_list: D002248:Carbon Monoxide