[Immune responsive features in patients with pulmonary tuberculosis complicated by intestinal dysbacteriosis].
Clinical and immunological studies made in 130 patients with various types of pulmonary tuberculosis ascertain that the absolute majority (90%) patients who begin to develop intestinal dysbacteriosis due to long-term chemotherapy have T-cell immunity impairments, which appears as their quantitative shortage and functional insufficiency. There is a marked decrease in T helper levels with subpopulation imbalance and lower Tx/Tc ratios. The applied complex of corrective means produces stimulating and correcting effects on cellular and humoral immunological responses, promotes the increase of T helper counts, by eliminating the imbalance of regulatory subpopulations of T lymphocytes and having a beneficial effect on the clinical and X-ray changes in pulmonary tuberculosis.
Lineva
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NPO "Phthisiology", Iakutia.
D000995:Antitubercular Agents / Q000009:adverse effects; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification; D001424:Bacterial Infections / Q000150:complications / Q000382:microbiology; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D007410:Intestinal Diseases / Q000209:etiology* / Q000276:immunology / Q000382:microbiology; D007422:Intestines / Q000382:microbiology; D008297:Male; D016176:T-Lymphocyte Subsets / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology*; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000276:immunology*
D000995:Antitubercular Agents; D007136:Immunoglobulins
Osobennosti immunologicheskoí reaktivnosti u bol'nykh tuberkulezom legkikh, oslozhnennym disbakteriozom kishechnika.