title: [Substantiation of MAC of crotonaldehyde in environmental air].
abstract: The reflex and resorptive effects of crotonaldehyde was studied. The maximum acceptable concentration (MAC) of crotonaldehyde was established to be 0.025 mg/m3, the mean daily MAC recommended to be 0.003 mg/m3, Hazard Class 2. It was shown that nasopharyngeal mucosal morphological changes in laboratory animals might serve as significant criteria for the action of the agent having an irritant effect.
authors.forename: L A
authors.initials: LA
authors.lastname: Tepikina
authors.forename: E L
authors.initials: EL
authors.lastname: Skvortsova
authors.forename: Z V
authors.initials: ZV
authors.lastname: Shipulina
authors.forename: A V
authors.initials: AV
authors.lastname: Kartashova
authors.forename: Iu N
authors.initials: IuN
authors.lastname: Mol'kov
authors.forename: N N
authors.initials: NN
authors.lastname: Sizova
mesh_terms: D000395:Air Pollutants, Occupational / Q000633:toxicity; D000447:Aldehydes / Q000633:toxicity; D000818:Animals; D002415:Cats; D005260:Female; D008452:Maximum Allowable Concentration; D051379:Mice; D008962:Models, Theoretical; D009297:Nasal Mucosa / Q000187:drug effects; D011817:Rabbits; D051381:Rats
chemical_list: D000395:Air Pollutants, Occupational; D000447:Aldehydes; C012796:2-butenal
vernacular_title: Obosnovanie PDK krotonovogo al'degida v atmosphernom vozdukhe.