Dynamic scintigraphy of bone and bone marrow in multiple myeloma patients with bone-marrow transplants.
OBJECTIVE
To determine whether dynamic registration at bone and bone-marrow scintigraphy produces additional information compared to subsequent static registrations of bone-marrow transplants in multiple myeloma patients.


METHODS
In a prospective study, 8 dynamic bone and 6 dynamic bone-marrow scintigraphies were performed in 10 patients. The dynamic scintigraphies were compared with conventional radiography, MR images, and static scintigraphies of bone and bone marrow.


RESULTS
No additional information was revealed by the dynamic registration method; on the contrary, 4 of the 8 known lesions were not discerned at dynamic registration. An incidental observation was that the time-activity curves of both radiopharmaceuticals had a specific pattern.


CONCLUSIONS
Dynamic registration at bone and bone-marrow scintigraphy was not useful for detecting disease in multiple myeloma lesions.
Agren
B
B
Department of Diagnostic Radiology, Huddinge University Hospital, Sweden.
Rudberg
U
U
Aspelin
P
P
D000328:Adult; D001853:Bone Marrow / Q000000981:diagnostic imaging*; D016026:Bone Marrow Transplantation / Q000000981:diagnostic imaging*; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000000981:diagnostic imaging* / Q000628:therapy; D011446:Prospective Studies; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; D013669:Technetium Tc 99m Medronate
D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; D013669:Technetium Tc 99m Medronate