title: Formation of homo- and heterooligomeric supramolecular structures by D-glyceraldehyde-3-phosphate dehydrogenase and lactate dehydrogenase in reversed micelles of aerosol OT in octane.
abstract: The supramolecular structure of oligomeric enzymes can be specifically regulated by changing the size of an inner cavity of Aerosol OT reversed micelles in octane. Both D-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and lactate dehydrogenase (LDH) reveal an ability to exist and function in monomeric, dimeric and tetrameric forms (homooligomers). Various heterooligomeric complexes, in particular, GAPDH monomer--LDH monomer, GAPDH dimer--LDH tetramer were detected in reversed micelles.
authors.affiliation: Department of Chemistry, Moscow State University, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Levashov
authors.forename: A V
authors.initials: AV
authors.lastname: Ugolnikova
authors.forename: M V
authors.initials: MV
authors.lastname: Ivanov
authors.forename: N L
authors.initials: NL
authors.lastname: Klyachko
mesh_terms: D000818:Animals; D002384:Catalysis; D004143:Dioctyl Sulfosuccinic Acid; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases / Q000737:chemistry* / Q000378:metabolism; D007770:L-Lactate Dehydrogenase / Q000737:chemistry* / Q000378:metabolism; D046911:Macromolecular Substances; D008823:Micelles; D009795:Octanes; D010446:Peptide Fragments / Q000737:chemistry* / Q000378:metabolism; D011108:Polymers; D011487:Protein Conformation; D011817:Rabbits; D012997:Solvents; D013501:Surface-Active Agents
chemical_list: D046911:Macromolecular Substances; D008823:Micelles; D009795:Octanes; D010446:Peptide Fragments; D011108:Polymers; D012997:Solvents; D013501:Surface-Active Agents; D004143:Dioctyl Sulfosuccinic Acid; C068142:glyceraldehyde 3-phosphate dehydrogenase (304-313); D007770:L-Lactate Dehydrogenase; D005987:Glyceraldehyde-3-Phosphate Dehydrogenases; C026728:octane