title: A comparative study on the functional properties of the wild European mouflon and domestic sheep hemoglobins.
abstract: The functional properties of Hb B of the wild European mouflon (Ovis gmelini musimon), Hb B of domestic sheep (Ovis aries), and Hb C isolated from anemic mouflon were investigated. Mouflon and sheep Hbs appear to be very similar in their response to organic anions and protons, whereas sheep Hb B displays an oxygen affinity lower than that of mouflon Hb B and sheep Hb A. Mouflon Hb B and Hb C, like sheep Hb A and Hb C, have similar efficiencies in transporting oxygen to the tissues. As in other ruminant Hbs, the effect of temperature on the oxygen affinity is slight. Data suggest that mouflon Hb B is not only structurally, but even functionally, more similar to sheep Hb A than to sheep Hb B.
authors.affiliation: Istituto di Chimica Biologica, Università di Cagliari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Corda
authors.forename: B
authors.initials: B
authors.lastname: Giardina
authors.forename: M
authors.initials: M
authors.lastname: Pellegrini
authors.forename: L
authors.initials: L
authors.lastname: Manca
authors.forename: A
authors.initials: A
authors.lastname: Olianas
authors.forename: M T
authors.initials: MT
authors.lastname: Sanna
authors.forename: A
authors.initials: A
authors.lastname: Fais
authors.forename: B
authors.initials: B
authors.lastname: Masala
mesh_terms: D000818:Animals; D006441:Hemoglobin A / Q000378:metabolism*; D006444:Hemoglobin C / Q000378:metabolism*; D006454:Hemoglobins / Q000378:metabolism*; D006863:Hydrogen-Ion Concentration; D010108:Oxyhemoglobins / Q000378:metabolism; D010641:Phenotype; D012756:Sheep / Q000097:blood*; D013696:Temperature; D013816:Thermodynamics
chemical_list: D006454:Hemoglobins; D010108:Oxyhemoglobins; D006444:Hemoglobin C; D006441:Hemoglobin A; C020622:hemoglobin B