title: [Angiostrongylosis in infants in Reunion and Mayotte. Apropos of 3 cases of eosinophilic meningitis including 1 fatal radiculo-myeloencephalitis with hydrocephalus].
abstract: BACKGROUND
  Eosinophilic meningitis caused by Angiostrongylus cantonensis is widespread in Southeast Asia and Pacific islands. Adults develop a transient meningitis with a benign course but severe or fatal disease may occur in pediatric patients.
  
  
  METHODS
  Case 1. A 11-month-old boy living in Mayotte island was hospitalized a few days with fever and skin rash following by seizure, coma, flaccid quadraplegia, absence of deep tendon reflexes, urinary retention and anal incontinence. Eosinophilia was observed in peripheral blood and cerebrospinal fluid. He further developed a triventricular hydrocephalus treated by ventriculoperitoneal shunt. The child died 3 weeks later. A serodiagnosis of angiostrongylus infestation was restrospectively established. Case reports 2 and 3.-Two infants, 10 and 11-month-old-boys, living in Reunion island, developed fever and vomitings, irritability and, for one of them, unilateral sixth cranial nerve palsy. There was eosinophilia in the peripheral blood and in the cerebrospinal fluid. All symptoms progressively disappeared with complete recovery. The suspected diagnosis of angiostrongylus infestation was confirmed by the serology.
  
  
  CONCLUSIONS
  We report the first case of Angiostrongylus cantonensis infection in the French island of Mayone (Comoro Islands) and we confirm the presence of this disease in Reunion island. In this Indian Ocean area, eosinophilic meningitis occurs most of the time in infants with sometimes severe radiculomyeloencephalitic forms.
authors.affiliation: Service de pédiatrie, centre hospitalier départemental F-Guyon, Saint-Denis, la Réunion, France.
authors.forename: D
authors.initials: D
authors.lastname: Graber
authors.forename: M C
authors.initials: MC
authors.lastname: Jaffar-Bandjee
authors.forename: T
authors.initials: T
authors.lastname: Attali
authors.forename: J
authors.initials: J
authors.lastname: Poisson
authors.forename: M
authors.initials: M
authors.lastname: Renouil
authors.forename: J L
authors.initials: JL
authors.lastname: Alessandri
authors.forename: J C
authors.initials: JC
authors.lastname: Combes
mesh_terms: D017185:Angiostrongylus cantonensis; D000818:Animals; D017507:Comoros; D004679:Encephalomyelitis / Q000209:etiology / Q000469:parasitology; D004802:Eosinophilia / Q000209:etiology / Q000469:parasitology*; D017809:Fatal Outcome; D006801:Humans; D006849:Hydrocephalus / Q000209:etiology / Q000469:parasitology; D007223:Infant; D008297:Male; D008581:Meningitis / Q000209:etiology / Q000469:parasitology*; D011843:Radiculopathy / Q000209:etiology / Q000469:parasitology; D017508:Reunion; D017206:Strongylida Infections / Q000150:complications / Q000175:diagnosis*
vernacular_title: L'angiostrongylose chez le nourrisson à la Réunion et à Mayotte. A propos de trois méningites à eosinophiles dont une radiculomyéloencéphalite fatale avec hydrocéphalie.