[The effect of polyunsaturated fatty acids of the omega-3 class on the late phase of the allergic reaction in bronchial asthma patients].
Placebo-controlled study of changes in the course of atopic bronchial asthma (ABA) induced by supplement of the diet with polyunsaturated fatty acids of omega-3 class in 13 patients compared to placebo-treated subjects allowed the conclusion on significant attenuation of late allergic response in patients who had taken eiconol for two weeks. The effects of the acids are explained by a comparative replacement of arachidonic acid in the membranes of cell effectors of the inflammation with omega-3 fatty acids leading to inhibition of production of inflammation lipid mediators.
Masuev
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D000293:Adolescent; D000328:Adult; D000485:Allergens; D018927:Anti-Asthmatic Agents / Q000627:therapeutic use*; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy*; D002908:Chronic Disease; D004042:Dietary Fats, Unsaturated / Q000627:therapeutic use*; D004341:Drug Evaluation; D004391:Dust / Q000009:adverse effects; D005395:Fish Oils / Q000627:therapeutic use*; D006801:Humans; D012130:Respiratory Hypersensitivity / Q000175:diagnosis / Q000188:drug therapy*; D013997:Time Factors
D000485:Allergens; D018927:Anti-Asthmatic Agents; D004042:Dietary Fats, Unsaturated; D004391:Dust; D005395:Fish Oils; C089938:eiconol
Vliianie polinenasyshchennykh zhirnykh kislot omega-3 klassa na pozdniuiu fazu allergicheskoĭ reaktsii y bol'nykh bronkhial'noĭ astmoĭ.