[KI-1-positive, anaplastic, large-cell lymphoma related to Hodgkin's disease].
We report a case of lymphoma associated with lung carcinoma that shows morphological and immunohistochemical features of anaplastic large cell Ki-1 positive lymphoma and Hodgkin's disease, with positivity for Ki-1 (CD-30) (characteristic of both lymphomas) and Leu-M1 (CD-15) (normally dosent absent in anaplastic lymphoma). This subtype of lymphoma is designated anaplastic large-cell Hodgkin's related lymphoma (ALCL related to HD) and is considered by some authors as a secondary anaplastic large-cell lymphoma.
Veiga
M
M
Servicio de Anatomía Patológica del Hospital Covadonga (Hospital Central de Asturias).
Fresno
M F
MF
Pérez del Río
M J
MJ
García
I
I
Madrigal
B
B
Herrero
A
A
D000951:Antigens, Neoplasm / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000473:pathology / Q000556:secondary; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006689:Hodgkin Disease / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D017730:Ki-1 Antigen / Q000032:analysis; D019394:Ki-67 Antigen / Q000032:analysis; D016256:Lewis X Antigen / Q000032:analysis; D008175:Lung Neoplasms; D017728:Lymphoma, Large-Cell, Anaplastic / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000737:chemistry / Q000473:pathology
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D017730:Ki-1 Antigen; D019394:Ki-67 Antigen; D016256:Lewis X Antigen
Linfoma anaplásico de células grandes Ki-1 positivo relacionado con Hodgkin.