title: Factors influencing blood loss in transurethral resection of the prostate (TURP): auditing TURP.
abstract: OBJECTIVE
  To assess the blood loss accompanying TURP and investigate its association with the resected weight of prostatic tissue, type of anaesthesia, type of presentation, histology, different surgeons and their differing techniques, and thus to reduce the morbidity associated with blood loss and transfusion.
  
  
  METHODS
  All prostatectomies carried out in a district general hospital were audited prospectively, recording the pre- and post-operative haemoglobin concentration (Hb), blood transfusions and the variables listed above. The audit was repeated a year later.
  
  
  RESULTS
  The peri-operative blood loss, as assessed by various indicators, was equivalent to a decrease in Hb of 10-15 g/L (8-11%). The weight of the resected prostatic tissue was the most important measurable factor in determining blood loss. Regional anaesthesia was associated with less blood loss than general anaesthesia. The added use of a suprapubic catheter for irrigation appeared to have a marginal advantage in large resections. The type of presentation, elective or otherwise, and the histological nature of the prostate did not influence blood loss. Smaller transfusions were probably avoidable in patients having smaller resections and a normal pre-operative Hb. On re-auditing, the overall transfusion rate was reduced from 10.8% to 8.2% and from 4.4% to 1% in patients having resections of < 30 g.
  
  
  CONCLUSIONS
  Blood transfusion can be reduced and rationalized. Patients with a normal pre-operative Hb and undergoing resections of < 30 g do not usually require transfusion. Regional anaesthesia is associated with less blood loss but its advantage is overshadowed in practice by the weight of the resected tissue. An audit of this type is repeatable and is useful in raising awareness, objectively assessing differences and advocating and assessing any changes made.
authors.affiliation: Urology Department, Torbay Hospital, UK.
authors.forename: M M
authors.initials: MM
authors.lastname: Kirollos
authors.forename: N
authors.initials: N
authors.lastname: Campbell
mesh_terms: D000368:Aged; D000765:Anesthesia, Conduction; D016063:Blood Loss, Surgical; D001803:Blood Transfusion; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008297:Male; D008485:Medical Audit; D011446:Prospective Studies; D011468:Prostatectomy / Q000009:adverse effects*; D011470:Prostatic Hyperplasia / Q000473:pathology / Q000601:surgery*; D014546:Urinary Catheterization
chemical_list: D006454:Hemoglobins