title: Synthesis of sodium androst-5-ene-17-one-3 beta-methylene sulfonate.
abstract: The synthesis of sodium androst-5-ene-17-one-3 beta-methylene sulfonate 2, a stable analog of memory-enhancing neurosteroid dehydroepiandrosterone sulfate, is described. The synthesis of compound 2 is carried out in six steps from dehydroepiandrosterone.
authors.affiliation: Division of Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA 15282, USA.
authors.forename: G H
authors.initials: GH
authors.lastname: Chu
authors.forename: P K
authors.initials: PK
authors.lastname: Li
mesh_terms: D019314:Dehydroepiandrosterone Sulfate / Q000138:chemical synthesis / Q000737:chemistry*
chemical_list: C108252:androst-5-ene-17-one-3-methylene sulfonic acid; D019314:Dehydroepiandrosterone Sulfate