title: Leukocyte-marrow scintigraphy in hyperostosis frontalis interna.
abstract: Hyperostosis frontalis interna is the term used to describe the thickening of the frontal bones of the skull. This thickening of the frontal bones is accompanied by an increase in the diploic space which results in an increased quantity of hematopoietically active marrow. Increased frontal bone uptake of labeled leukocytes has been reported in this condition, and the symmetric appearance of this activity may suggest its benign etiology. We have encountered a case of hyperostosis frontalis interna in which the uptake of labeled leukocytes was asymmetric and marrow scintigraphy confirmed that the activity seen was due to marrow not infection.
authors.affiliation: Division of Nuclear Medicine, Long Island Jewish Medical Center, New Hyde Park, New York 11040, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Torres
authors.forename: C J
authors.initials: CJ
authors.lastname: Palestro
mesh_terms: D000368:Aged; D001853:Bone Marrow / Q000000981:diagnostic imaging*; D005260:Female; D005624:Frontal Bone / Q000000981:diagnostic imaging*; D006801:Humans; D006957:Hyperostosis Frontalis Interna / Q000000981:diagnostic imaging*; D007205:Indium Radioisotopes; D007962:Leukocytes; D011877:Radionuclide Imaging; D013671:Technetium Tc 99m Sulfur Colloid
chemical_list: D007205:Indium Radioisotopes; D013671:Technetium Tc 99m Sulfur Colloid