Lamotrigine control of central pain.
Central pain remains a therapeutic challenge. We report beneficial effects of lamotrigine, a novel antiepileptic drug, on four patients suffering from long-standing central pain. Analgesia may be due to interference with glutamatergic transmission.
Canavero
Sergio
S
Pain Relief Unit, Department of Neurosciences, University of Turin, Ospedale Molinette,Turin,Italy.
Bonicalzi
Vincenzo
V
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000700:Analgesics / Q000627:therapeutic use*; D000927:Anticonvulsants / Q000627:therapeutic use*; D002493:Central Nervous System Diseases / Q000150:complications*; D005260:Female; D006801:Humans; D000077213:Lamotrigine; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D014227:Triazines / Q000627:therapeutic use*
D000700:Analgesics; D000927:Anticonvulsants; D014227:Triazines; D000077213:Lamotrigine