Properties of biomolecules measured from atomic force microscope images: a review.
AFM images can be used to obtain quantitative or qualitative information about the properties of biomaterials. Examples presented here are: (1) Persistence length measurements of moving and stationary DNA molecules. (2) Force mapping to measure properties such as the elasticity of cells and vesicles. (3) Phase mode imaging to detect variations in materials and properties of the sample surface. (4) Imaging of surfaces at different constant forces.
Hansma
H G
HG
Department of Physics, University of California, Santa Barbara 93106, USA.
Kim
K J
KJ
Laney
D E
DE
Garcia
R A
RA
Argaman
M
M
Allen
M J
MJ
Parsons
S M
SM
D000818:Animals; D010582:Bacteriophage lambda / Q000737:chemistry; D002482:Cellulose / Q000648:ultrastructure; D004247:DNA / Q000648:ultrastructure*; D012321:DNA-Directed RNA Polymerases / Q000648:ultrastructure; D006801:Humans; D008297:Male; D018625:Microscopy, Atomic Force; D010316:Particle Size; D013077:Sperm Head / Q000648:ultrastructure; D013499:Surface Properties; D013572:Synaptic Vesicles / Q000648:ultrastructure*; D014101:Torpedo
D002482:Cellulose; D004247:DNA; D012321:DNA-Directed RNA Polymerases