title: Factors associated with term low birthweight in Cardiff, Wales.
abstract: This project was undertaken to examine the associations of a number of risk factors with impaired fetal growth, exemplified by delivery of a low-birthweight infant at term (TLBW). Utilising a large database of largely homogeneous (white) births in Wales, the Cardiff Births Survey, multivariable analysis by logistic regression examined the relative importance of these risk variables. Significant independent associations with TLBW were found (in decreasing order of magnitude) for low maternal weight, pre-eclampsia, smoking, short maternal height, late pregnancy bleeding, early pregnancy bleeding, history of a previous stillbirth, primiparity and older maternal age. In this population, risk of TBLW was associated with a number of demographic, medical and social factors. Of these, only smoking is likely to be modified by intervention.
authors.affiliation: Department of Obstetrics and Gynecology, Bowman Gray School of Medicine, Wake Forest University Winston-Salem, NC 27157-1066, USA.
authors.forename: P J
authors.initials: PJ
authors.lastname: Meis
authors.forename: R
authors.initials: R
authors.lastname: Michielutte
authors.forename: T J
authors.initials: TJ
authors.lastname: Peters
authors.forename: H B
authors.initials: HB
authors.lastname: Wells
authors.forename: R E
authors.initials: RE
authors.lastname: Sands
authors.forename: E C
authors.initials: EC
authors.lastname: Coles
authors.forename: K A
authors.initials: KA
authors.lastname: Johns
mesh_terms: D000293:Adolescent; D000328:Adult; D001724:Birth Weight; D016001:Confidence Intervals; D003430:Cross-Sectional Studies; D005260:Female; D005317:Fetal Growth Retardation / Q000453:epidemiology*; D006306:Health Surveys; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D016015:Logistic Models; D008423:Maternal Age; D016017:Odds Ratio; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology; D017584:Reproductive History; D012189:Retrospective Studies; D012307:Risk Factors; D012907:Smoking / Q000453:epidemiology; D012959:Socioeconomic Factors; D014852:Wales / Q000453:epidemiology