[The endoscopic assessment of the effect of ranitidine and pirenzepine on the manifestations of the gastropathy induced by nonsteroidal anti-inflammatory preparations].
Two antiulcer drugs, ranitidine and pirenzepine belonging to blockers of H2-receptors and selective M-cholinoblockers, respectively, were compared by efficacy against erosive and ulcer lesions in the upper gastrointestinal mucosa. A total of 62 rheumatics were examined. In patients treated by nonsteroid antiinflammatory drugs irrespectively of the mode of their administration the highest response was shown by ranitidine while pirenzepine efficacy proved poor.
Karateev
A E
AE
Murav'ev
Iu V
IuV
Nasonova
V A
VA
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D005260:Female; D005773:Gastroscopy; D006635:Histamine H2 Antagonists / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010890:Pirenzepine / Q000627:therapeutic use*; D011899:Ranitidine / Q000627:therapeutic use*; D012216:Rheumatic Diseases / Q000150:complications; D013276:Stomach Ulcer / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000897:Anti-Ulcer Agents; D006635:Histamine H2 Antagonists; D010890:Pirenzepine; D011899:Ranitidine
Endoskopicheskaia otsenka vliianiia ranitidina i pirenzepina na gastropatii, vyzvannoĭ nesteroidnymi protivovospalitel'nymi preparatami.