[Who are the "non-dippers": an insight from the ambulatory monitoring of arterial pressure in heart transplant patients].
This study was performed in order to define who are the "non-dippers", knowing that their present definition does not imply any explanation about the mechanisms. The investigation was performed on 34 heart transplanted patients, 28 males (mean age 52 +/- 11 years) and 6 women (mean age 35 +/- 14 years), knowing that the "non-dippers" were described as the hypertensives who are devoid of the expected nocturnal fall in blood pressure (BP). The "non-dipping" phenomenon was investigated by exploring the BP 24-h pattern via ambulatory non-invasive BP monitoring, and by applying the rhythmometric analysis for quantifying the BP circadian rhythm. The study provided evidence that the "non-dippers" can be found among the hypertensives as well as the normotensives, suggesting that high BP is not a necessary condition for the "non-dipping" phenomenon, and vice versa. Both the normotensive and hypertensive "non-dippers" were seen to show stereotypic changes in BP circadian rhythm. There are normotensive and hypertensive "non-dippers" with or without the BP circadian rhythm. The "rhythmic non-dippers" show a BP circadian rhythm which is inverted in phase or demodulated in amplitude. The "non-dippers" are, thus, a heterogeneous category.
Cugini
P
P
Semeiotica e Metodologia Medica, Università La Sapienza, Roma.
Chiera
A
A
Scibilia
G
G
Laurenti
A
A
Papalia
U
U
Marino
B
B
Voci
P
P
Petrangeli
C M
CM
Capodaglio
P F
PF
Fontana
S
S
Ranone
G
G
Schiavone
R
R
D000328:Adult; D018660:Blood Pressure Monitoring, Ambulatory / Q000706:statistics & numerical data; D002940:Circadian Rhythm; D005260:Female; D016027:Heart Transplantation / Q000502:physiology* / Q000706:statistics & numerical data; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis
Chi sono i "non-dipper": un approfondimento dal monitoraggio ambulatorio della pressione arteriosa nei cardiotrapiantati.