Hippocampal CA1-region-restricted knockout of NMDAR1 gene disrupts synaptic plasticity, place fields, and spatial learning.
Tonegawa
S
S
Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge 02139, USA.
Tsien
J Z
JZ
McHugh
T J
TJ
Huerta
P
P
Blum
K I
KI
Wilson
M A
MA
D000818:Animals; D018891:Dentate Gyrus / Q000502:physiology; D004594:Electrophysiology; D006624:Hippocampus / Q000378:metabolism*; D007858:Learning / Q000502:physiology*; D051379:Mice; D018345:Mice, Knockout; D009154:Mutation / Q000502:physiology; D009473:Neuronal Plasticity / Q000502:physiology*; D016194:Receptors, N-Methyl-D-Aspartate / Q000096:biosynthesis / Q000235:genetics*; D013028:Space Perception / Q000502:physiology*; D013569:Synapses / Q000502:physiology*
D016194:Receptors, N-Methyl-D-Aspartate