title: Effect of balloon angioplasty in femoropopliteal arteries assessed by intravascular ultrasound.
abstract: OBJECTIVE
  To study the effects of balloon angioplasty (PTA) of the femoropopliteal artery with intravascular ultrasound (IVUS).
  
  
  METHODS
  Corresponding IVUS cross-sections (n = 1033) obtained before and after PTA from 115 procedures were analysed. Vascular damage including plaque rupture, dissection and media rupture was assessed. Free lumen area (FLA), media-bounded area (MBA) and plaque area (PLA) were measured.
  
  
  RESULTS
  After PTA vascular damage was seen at the target site in 83 (72%) arteries: plaque rupture in 30 (26%), dissection in 66 (57%) and media rupture in 20 (17%) arteries. The FLA increased from 5.4 +/- 3.4 mm2 to 14.1 +/- 5.0 mm2 (p < 0.001), MBA increased from 26.9 +/- 10.0 mm2 to 32.9 +/- 10.7 mm2 (p < 0.001) and PLA decreased from 21.6 +/- 8.5 mm2 to 18.8 +/- 8.0 mm2 (p < 0.001). The increase in MBA accounted for 68% of lumen gain. The frequency of vascular damage and the relative contribution of MBA increase and PLA decrease to luminal gain were not different in procedures with balloon diameter < or = 5 mm and > or = 6 mm.
  
  
  CONCLUSIONS
  Vascular damage is common following PTA. Lumen gain is mainly due to vessel expansion and, to a lesser extent, to a decrease in plaque area.
authors.affiliation: University Hospital Rotterdam-Dijkzigt, The Netherlands.
authors.forename: A
authors.initials: A
authors.lastname: van der Lugt
authors.forename: E J
authors.initials: EJ
authors.lastname: Gussenhoven
authors.forename: W P
authors.initials: WP
authors.lastname: Mali
authors.forename: J A
authors.initials: JA
authors.lastname: Reekers
authors.forename: J L
authors.initials: JL
authors.lastname: Seelen
authors.forename: A V
authors.initials: AV
authors.lastname: Tielbeek
authors.forename: H
authors.initials: H
authors.lastname: Pieterman
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000784:Aortic Dissection / Q000000981:diagnostic imaging / Q000209:etiology*; D000800:Angioplasty, Balloon / Q000009:adverse effects*; D001157:Arterial Occlusive Diseases / Q000628:therapy*; D004730:Endothelium, Vascular / Q000293:injuries; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000293:injuries*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery / Q000000981:diagnostic imaging / Q000293:injuries*; D018084:Ultrasonography, Interventional / Q000379:methods