title: [A case of tabes dorsalis observed in an HTLV-1 carrier].
abstract: We report a case of a 53-year-old female HTLV-1 carrier with tabes dorsalis. In addition to typical symptoms of tabes dorsalis, she presented HTLV-1 associated myelopathy (HAM) like clinical features such as sensory disturbance with thoracic sensory levels and bladder disturbance (pollakiuria). Although penicillin treatment did not improve in her neurological symptoms, steroid therapy was effective especially in HAM like symptoms. The CSF neopterin level was markedly decreased after steroid therapy, indicating that inflammation in the spinal cord was settled down after treatment. Our case suggests that CNS infection like tabes dorsalis may be modified by HTLV-1 infection and then present some atypical clinical features based upon altered immunological aspects of HTLV-1 carriers.
authors.affiliation: Department of Neurology, National Sanatorium Okinawa Hospital.
authors.forename: A
authors.initials: A
authors.lastname: Nagata
authors.forename: M
authors.initials: M
authors.lastname: Saito
authors.forename: N
authors.initials: N
authors.lastname: Kanzato
authors.forename: T
authors.initials: T
authors.lastname: Matsuzaki
authors.forename: M
authors.initials: M
authors.lastname: Suehara
mesh_terms: D002353:Carrier State; D005260:Female; D006801:Humans; D008875:Middle Aged; D009894:Opportunistic Infections / Q000150:complications*; D015493:Paraparesis, Tropical Spastic / Q000150:complications*; D013606:Tabes Dorsalis / Q000150:complications*