title: [Chronic myeloid leukemia developing into a multifocal extramedullary blast crisis].
abstract: A 47-old male with accelerated-phase chronic myelogenous leukaemia is presented. In spite of a good response to hydroxyurea and interferon treatment, the patient developed multiple foci of granulocytic sarcoma as a special form of blastic crisis. A review was carried out of the different aspects of this entity, stress being laid on the diagnostic characteristics and the current therapeutic approach in such cases.
authors.affiliation: Servicio Regional de Hematología y Hemoterapia, Hospital Miguel Servet, Zaragoza.
authors.forename: M
authors.initials: M
authors.lastname: Tapia
authors.forename: J C
authors.initials: JC
authors.lastname: García Zueco
authors.forename: A
authors.initials: A
authors.lastname: Gómez Ara
authors.forename: P
authors.initials: P
authors.lastname: Lanau
authors.forename: P
authors.initials: P
authors.lastname: Giraldo
mesh_terms: D001752:Blast Crisis / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D001859:Bone Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D017809:Fatal Outcome; D006801:Humans; D015465:Leukemia, Myeloid, Accelerated Phase / Q000188:drug therapy / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008875:Middle Aged
vernacular_title: Leucemia mieloide crónica con evolución a crisis blástica extramedular politópica.