title: Inactivation of rotavirus by new polymeric water disinfectants.
abstract: Two new insoluble polymeric materials were evaluated for their efficacies in inactivating rotavirus in flowing water in a biocidal filter application. The two polymers are N-chloro and N-bromo derivatives of a poly-styrene hydantoin prepared from commercial poly-styrene. The studies were conducted for rotavirus in halogen demand-free water at pH 7.0, 25 degrees C and Environmental Protection Agency (EPA) Test Water no. 2 at pH 9.0, 4 degrees C which contained heavy halogen demand. The range of flow rates studied was 0.16-1.22 ml s-1 corresponding to contact times in the range of 4-24 s. Both of the polymers were effective in inactivating rotavirus, the N-bromo derivative providing a 4-6 log reduction under the test conditions. The materials may be useful as supplemental filters for hand-held water purification units.
authors.affiliation: Department of Pathobiology, Auburn University, AL 36849, USA.
authors.forename: V S
authors.initials: VS
authors.lastname: Panangala
authors.forename: L
authors.initials: L
authors.lastname: Liu
authors.forename: G
authors.initials: G
authors.lastname: Sun
authors.forename: S D
authors.initials: SD
authors.lastname: Worley
authors.forename: A
authors.initials: A
authors.lastname: Mitra
mesh_terms: D004202:Disinfectants / Q000494:pharmacology*; D011137:Polystyrenes; D012401:Rotavirus / Q000187:drug effects*; D014462:Ultrafiltration / Q000379:methods*; D010948:Viral Plaque Assay; D018508:Water Purification / Q000379:methods
chemical_list: D004202:Disinfectants; D011137:Polystyrenes