Kawaguchipeptin B, an antibacterial cyclic undecapeptide from the cyanobacterium Microcystis aeruginosa.
Kawaguchipeptin B, an antibacterial cyclic undecapeptide, was isolated from the cultured cyanobacterium Microcystis aeruginosa (NIES-88). Its structure was elucidated as 1 on the basis of 2D NMR data and chemical degradation. Kawaguchipeptin B (1) inhibited the growth of the Gram-positive bacterium Staphylococcus aureus at a concentration of 1 microgram/mL (MIC).
Ishida
K
K
Laboratory of Marine Biochemistry, Graduate School of Agricultural Life Sciences, University of Tokyo, Japan.
Matsuda
H
H
Murakami
M
M
Yamaguchi
K
K
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D002849:Chromatography, Gas; D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D046931:Microcystis / Q000737:chemistry*; D010455:Peptides; D010456:Peptides, Cyclic; D011487:Protein Conformation; D013211:Staphylococcus aureus / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D010455:Peptides; D010456:Peptides, Cyclic; C107719:kawaguchipeptin B