title: Conjunctival injection, episcleral vessel dilation, and subconjunctival hemorrhage in patients with new tsutsugamushi disease.
abstract: Tsutsugamushi disease is found in two types: classical and new. There have been very few reports describing the ocular findings in patients with the new form. We have described four patients with this type, selected according to their clinical and laboratory findings, including immunofluorescent titers and polymerase chain reaction results. Eyes were examined by standard ophthalmic procedures. Patient 1 had bilateral conjunctival injection and subconjunctival hemorrhage; patients 2-4 had conjunctival injection and episcleral vessel dilation bilaterally. We believe that conjunctival injection is found in most eyes of patients with new tsutsugamushi disease.
authors.affiliation: Department of Ophthalmology, Asahi General Hospital, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Kato
authors.forename: K
authors.initials: K
authors.lastname: Watanabe
authors.forename: M
authors.initials: M
authors.lastname: Katori
authors.forename: Y
authors.initials: Y
authors.lastname: Terada
authors.forename: S
authors.initials: S
authors.lastname: Hayasaka
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003228:Conjunctiva / Q000098:blood supply* / Q000187:drug effects / Q000473:pathology; D003229:Conjunctival Diseases / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D004269:DNA, Bacterial / Q000032:analysis; D004108:Dilatation, Pathologic / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006470:Hemorrhage / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008911:Minocycline / Q000627:therapeutic use; D012285:Orientia tsutsugamushi / Q000235:genetics / Q000276:immunology; D016133:Polymerase Chain Reaction; D012590:Sclera / Q000098:blood supply* / Q000187:drug effects / Q000473:pathology; D012612:Scrub Typhus / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D008911:Minocycline