title: Antigen presentation: mixing oil and water.
abstract: Studies of the cellular immunology and protein structure of human and mouse CD1 proteins reveal these to be a family of antigen-presenting molecules that allow T cells to recognize lipid and glycolipid antigens of microbial pathogens.
authors.affiliation: Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
authors.forename: S A
authors.initials: SA
authors.lastname: Porcelli
authors.forename: M B
authors.initials: MB
authors.lastname: Brenner
mesh_terms: D000818:Animals; D017951:Antigen Presentation / Q000502:physiology*; D018949:Antigens, CD1 / Q000378:metabolism*; D002240:Carbohydrate Sequence; D006801:Humans; D008055:Lipids / Q000737:chemistry / Q000276:immunology; D051379:Mice; D008954:Models, Biological; D008969:Molecular Sequence Data; D015394:Molecular Structure; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D018949:Antigens, CD1; D008055:Lipids