title: Severe malabsorption in autoimmune polyendocrinopathy-candidosis-ectodermal dystrophy syndrome successfully treated with immunosuppression.
abstract: A 15 year old boy with autoimmune polyendocrinopathy-candidosis-ectodermal dystrophy syndrome suffered recurrent episodes of severe intractable diarrhoea, steatorrhoea, and hypocalcaemia. The only treatment modality, which controlled the malabsorption syndrome, was immunosuppression with intravenous high dose methylprednisolone and oral methotrexate maintenance therapy.
authors.affiliation: Department of Paediatrics, Chaim Sheba Medical Centre, Tel-Hashomer, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Padeh
authors.forename: R
authors.initials: R
authors.lastname: Theodor
authors.forename: A
authors.initials: A
authors.lastname: Jonas
authors.forename: J H
authors.initials: JH
authors.lastname: Passwell
mesh_terms: D000293:Adolescent; D001327:Autoimmune Diseases / Q000150:complications*; D004359:Drug Therapy, Combination; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008286:Malabsorption Syndromes / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D008775:Methylprednisolone / Q000627:therapeutic use; D016884:Polyendocrinopathies, Autoimmune / Q000150:complications*; D012008:Recurrence
chemical_list: D007166:Immunosuppressive Agents; D008775:Methylprednisolone; D008727:Methotrexate