Mouse models for the study of human hair loss.
A comparison has been presented to illustrate many of the similarities in patterns of disease between mouse and human hair follicle diseases and how various mouse mutations can be used as research tools to investigate these observations. The powerful genetic tools available for investigating mouse mutations and human homologues will continue to result in many breakthroughs in the understanding of hair follicle biology and pathology. Many more mouse mutations are available than are described here. Information on these mutations fills books and computer databases, providing an unlimited resource.
Sundberg
J P
JP
Jackson Laboratory, Bar Harbor, Maine, USA.
King
L E
LE
D000505:Alopecia / Q000209:etiology* / Q000503:physiopathology; D000818:Animals; D002921:Cicatrix / Q000209:etiology; D004195:Disease Models, Animal; D006197:Hair / Q000637:transplantation; D006628:Hirsutism / Q000503:physiopathology; D006801:Humans; D051379:Mice; D014183:Transplantation, Heterologous