[The use of a new marker and test systems for the diagnosis of lung cancer with a study of bronchoalveolar washings].
Diagnostic value of enzyme immunoassays and immunoagglutination kits based on monoclonal antibodies ICO 25 was investigated. Antigen CAg 25 occurred in minimal quantities (5 micrograms/ml maximum) or was absent in the bronchoalveolar lavage of patients with bronchial asthma, chronic bronchitis or free of pulmonary affection. The concentration 9-19 micrograms/ml was registered in epidermoid bronchial cancer and peripheral lung cancer. It is stated that test systems able to detect a new antigen CAg 25 in BAL are diagnostically significant.
Vikha
G V
GV
Romanova
L K
LK
Poletaeva
O A
OA
Meshandin
A G
AG
Timofeeva
O I
OI
Ovcharenko
S I
SI
Zavodnov
V Ia
VIa
D000372:Agglutination Tests; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000032:analysis*; D001249:Asthma / Q000175:diagnosis; D014408:Biomarkers, Tumor / Q000032:analysis*; D001991:Bronchitis / Q000175:diagnosis; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry*; D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay; D005069:Evaluation Studies as Topic; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D011933:Reagent Kits, Diagnostic
D015295:Antigens, Tumor-Associated, Carbohydrate; D014408:Biomarkers, Tumor; D011933:Reagent Kits, Diagnostic
Ispol'zovanie novogo markera i test-sistem dlia diagnostiki raka legkogo pri issledovanii bronkhoal'veoliarnykh smyvov.