title: Lower extremity macrovascular disease in diabetes.
abstract: Lower extremity macrovascular disease is more common and progresses more rapidly in the presence of diabetes and has a characteristic peritibial distribution with sparing of the foot arteries. The biology of the diabetic foot is compromised, thereby making it more susceptible to injury. Hence, compromises in perfusion have a greater significance, warranting an aggressive approach to revascularization.
authors.affiliation: Beth Israel Medical Center, Harvard Medical School, Boston, MA, USA.
authors.forename: S
authors.initials: S
authors.lastname: Arora
authors.forename: F W
authors.initials: FW
authors.lastname: LoGerfo
mesh_terms: D001157:Arterial Occlusive Diseases / Q000150:complications / Q000628:therapy; D001161:Arteriosclerosis / Q000150:complications / Q000503:physiopathology; D048909:Diabetes Complications; D003920:Diabetes Mellitus / Q000503:physiopathology; D017719:Diabetic Foot / Q000503:physiopathology; D003929:Diabetic Neuropathies / Q000503:physiopathology; D006801:Humans; D007866:Leg; D012039:Regional Blood Flow; D014652:Vascular Diseases / Q000150:complications* / Q000503:physiopathology