[The joint action of nitrates and gamma radiation on the blood plasma proteinase-inhibiting and antioxidative systems in rats].
The separate and combine influence of nitrates (40 mg of natrium nitrate) 100 g of body mass during 60 days) and gamma radiation (3 Gy) on condition of proteolytic and antioxidative blood plasma systems of rats have been investigated. There are were increase of total proteolytic activity (TPA) on 3-day, adaptive increase of alpha-antiproteinase inhibitor (API) on 7- and 14-day after factors separate action and tendency to increase TPA together with the invariable content of API after combine influence. The decrease of alpha-2-macroglobulin level on 14-day after all influences and more significantly after combination of factors action have been also shown. The decrease of antioxidant system and system of free radicals inactivation have been observed.
Kirpichenok
L N
LN
Gidranovich
L G
LG
Kheĭdorov
V P
VP
D000818:Animals; D005609:Free Radicals / Q000097:blood / Q000528:radiation effects; D005720:Gamma Rays; D008163:Luminescent Measurements; D009566:Nitrates / Q000494:pharmacology*; D010084:Oxidation-Reduction / Q000187:drug effects / Q000528:radiation effects; D011480:Protease Inhibitors / Q000097:blood / Q000528:radiation effects*; D051381:Rats; D013997:Time Factors; D000515:alpha 1-Antitrypsin / Q000032:analysis / Q000187:drug effects / Q000528:radiation effects; D000511:alpha-Macroglobulins / Q000032:analysis / Q000187:drug effects / Q000528:radiation effects
D005609:Free Radicals; D009566:Nitrates; D011480:Protease Inhibitors; D000515:alpha 1-Antitrypsin; D000511:alpha-Macroglobulins; C031618:sodium nitrate
Sochetannoe vozdeĭstvie nitratov i gamma-izlucheniia na proteinazoingibitornuiu i antiokislitel'nuiu sistemy plazmy krovi krys.