title: Tricompartmental kinetics of the organophosphorous pesticide dimethoate.
abstract: We present a study on the distribution and persistence of the organophosphorous pesticide, dimethoate, in the Wistar rat. Dimethoate's levels in blood and tissues were determined using gas chromatography with a NPD detector. The toxicokinetic profile was estimated by non-linear regression using the software program PCNONLIN, which concluded that a tricompartmental model best described dimethoate's behavior in the rat body.
authors.affiliation: Instituto Nacional de Toxicologia, Sevilla, Spain.
authors.forename: R
authors.initials: R
authors.lastname: Garcia-Repetto
authors.forename: D
authors.initials: D
authors.lastname: Martinez
authors.forename: M
authors.initials: M
authors.lastname: Repetto
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000378:metabolism; D002849:Chromatography, Gas; D004117:Dimethoate / Q000493:pharmacokinetics*; D006207:Half-Life; D007306:Insecticides / Q000493:pharmacokinetics*; D008099:Liver / Q000378:metabolism; D008297:Male; D018482:Muscle, Skeletal / Q000378:metabolism; D051381:Rats; D017208:Rats, Wistar; D014018:Tissue Distribution
chemical_list: D007306:Insecticides; D004117:Dimethoate