title: Necrotizing fasciitis and myonecrosis in early childhood: a report of three patients.
abstract: Necrotizing fasciitis (NF) is a rare and life-threatening disease. It usually presents as a postoperative complication, but rarely appears following trauma or without apparent cause. Over a period of 2 years we have treated three infants with NF, aged 15, 5, and 30 months, respectively. Two patients developed this complication following minor trauma while the third was post-elective bilateral inguinal hernia repair. The micro-organisms isolated were Staphylococcus aureus with Enterococcus durans in one patient, beta-hemolytic streptococcus in a second, and Staph. aureus in the third. The cornerstone of therapy is prompt, early, aggressive surgical debridement of the massive necrotic tissue and repeated debridement if necessary, with appropriate parenteral antibiotic therapy and hyperalimentation. All three patients survived. Early recognition of this life-threatening situation is mandatory in achieving survival.
authors.affiliation: Department of Pediatric Surgery, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
authors.forename: J
authors.initials: J
authors.lastname: Mordehai
authors.forename: E
authors.initials: E
authors.lastname: Kurzbart
authors.forename: Z
authors.initials: Z
authors.lastname: Cohen
authors.forename: A J
authors.initials: AJ
authors.lastname: Mares
mesh_terms: D000900:Anti-Bacterial Agents; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003646:Debridement; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D019115:Fasciitis, Necrotizing / Q000453:epidemiology / Q000382:microbiology / Q000628:therapy; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D018482:Muscle, Skeletal / Q000473:pathology; D009336:Necrosis; D010289:Parenteral Nutrition, Total; D016038:Skin Transplantation
chemical_list: D000900:Anti-Bacterial Agents