Development of a malignant peripheral nerve sheath tumor following treatment for testicular seminoma.
A novel case is reported in which an S2 nerve root malignant peripheral nerve sheath tumor was diagnosed approximately 8 years after treatment for Stage I testicular seminoma. This patient underwent right orchiectomy and subsequent irradiation therapy to the periaortic region, including the sacrum. Postoperative radiation therapy likely played a role in the development of this second malignancy.
West
D A
DA
Division of Urology, St. Louis University School of Medicine, Missouri, USA.
Parra
R O
RO
Manepalli
A
A
Bernardi
R J
RJ
Cummings
J M
JM
D000328:Adult; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary / Q000175:diagnosis; D018317:Nerve Sheath Neoplasms / Q000175:diagnosis; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis; D018239:Seminoma / Q000628:therapy*; D013736:Testicular Neoplasms / Q000628:therapy*