title: [Repolarisation anomalies simulating anterior myocardial infarction during ischemic cerebrovascular accident].
abstract: The authors report the case of a woman admitted to hospital for minor trauma of the left hip and who presented major ST segment elevation on the second day suggesting an acute anterior wall myocardial infarction at the same time as a cerebrovascular accident. Complementary investigations and follow-up excluded the diagnosis of myocardial infarction with normalisation of the ECG on the 5th day. ECG changes during cerebrovascular accidents may be very variable ranging from extrasystoles to ST elevation mimicking myocardial infarction. They carry a poor prognosis with an increased risk of sudden death necessitating continuous ECG monitoring until the ECG reverts to normal. The cardiac involvement is not ischaemic but due to disease of the insular cortex of the brain which induces myocytolysis (centered around the intra-cardiac nerve endings) due to the sudden liberation of catecholamines. These lesions may be treated by propranolol or phentolamine.
authors.affiliation: Service de cardiologie, CHU Purpan, Toulouse.
authors.forename: P
authors.initials: P
authors.lastname: Berdague
authors.forename: H
authors.initials: H
authors.lastname: Mhenni
authors.forename: Z
authors.initials: Z
authors.lastname: Smiri
authors.forename: H
authors.initials: H
authors.lastname: Haouala
authors.forename: N
authors.initials: N
authors.lastname: Chebbi
authors.forename: M
authors.initials: M
authors.lastname: Guediche
authors.forename: M
authors.initials: M
authors.lastname: Delay
authors.forename: J
authors.initials: J
authors.lastname: Puel
mesh_terms: D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D002540:Cerebral Cortex / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D003937:Diagnosis, Differential; D004562:Electrocardiography; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006801:Humans; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000503:physiopathology; D010646:Phentolamine / Q000008:administration & dosage; D011379:Prognosis; D011433:Propranolol / Q000008:administration & dosage; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000317:Adrenergic alpha-Antagonists; D000319:Adrenergic beta-Antagonists; D011433:Propranolol; D010646:Phentolamine
vernacular_title: Anomalies de la repolarisation simulant un infarctus du myocarde antérieur au cours d'un accident vasculaire cérébral ischémique.