title: [Postpartum thyroiditis and Basedow disease].
abstract: BACKGROUND
  The postpartum period is characterized by a rebound in autoimmunity secondary to immune tolerance induced by pregnancy, creating favorable conditions for flare up of Graves' disease or autoimmune thyroiditis. Postpartum thyroiditis is a recognized clinical entity.
  
  
  METHODS
  Six years after onset of Graves' disease treated with antithyroid drugs, a 25-year-old woman had a high serum level of antithyroperoxidase antibodies a few months before she became pregnant. Six weeks after delivery, she developed signs of hyperthyroidism and goiter. The diagnosis of postpartum thyroiditis was retained. Her condition regressed spontaneously to euthyroidism then hypothyroidism.
  
  
  CONCLUSIONS
  The therapeutic options involved underline the importance of distinguishing between Graves' disease and postpartum thyroiditis. The diagnosis of postpartum thyroiditis is based on history taking, clinical findings, and laboratory tests, especially isotope uptake.
authors.affiliation: Clinique d'Endocrinologie, Hôtel-Dieu, Nantes.
authors.forename: C
authors.initials: C
authors.lastname: Agard
authors.forename: L
authors.initials: L
authors.lastname: Chaillous
authors.forename: A
authors.initials: A
authors.lastname: Murat
authors.forename: D
authors.initials: D
authors.lastname: Tranchant
authors.forename: B
authors.initials: B
authors.lastname: Charbonnel
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006111:Graves Disease / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D006980:Hyperthyroidism / Q000209:etiology / Q000503:physiopathology; D011247:Pregnancy; D011644:Puerperal Disorders / Q000175:diagnosis* / Q000503:physiopathology; D012008:Recurrence; D013967:Thyroiditis, Autoimmune / Q000175:diagnosis* / Q000503:physiopathology
vernacular_title: Thyroïdite du post-partum et maladie de Basedow.