title: Pathophysiology of fever. Part 1: The role of cytokines.
abstract: Because of advanced molecular physiology techniques, there is new information about how fever affects the body. Now, fever is identified as a cascade of physiologic events, not just a single symptom. This article, the first in a set of two on the physiology of fever, focuses on the role of cytokines as the trigger for the physiologic cascade of fever. (Watch for Part 2 in the next issue of DCCN, which challenges the assumption that cooling interventions are appropriate for all febrile patients.
authors.affiliation: University of North Carolina at Chapel Hill, School of Nursing, USA.
authors.forename: P J
authors.initials: PJ
authors.lastname: Rowsey
mesh_terms: D001833:Body Temperature Regulation / Q000502:physiology; D016207:Cytokines / Q000145:classification / Q000276:immunology*; D005334:Fever / Q000276:immunology* / Q000451:nursing / Q000503:physiopathology; D006801:Humans
chemical_list: D016207:Cytokines