Synthesis, antimicrobial and genotoxic properties of some benzoimidazole derivatives.
A number of 1H-benzoimidazol-2-ylamine and of 1-methyl-1H-benzoimidazol-2-ylamine derivatives were synthesized and the crystal and molecular structure of N-[4-(2-amino-benzoimidazole-1-sulfonyl)-phenyl] acetamide was determined by X-ray diffraction analysis. The compounds obtained were investigated for antimicrobial and genotoxic activities.
Benvenuti
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S
Dipartimento di Scienze Farmaceutiche, Università di Modena.
Severi
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F
Sacchetti
A
A
Melegari
M
M
Vampa
G
G
Zani
F
F
Mazza
P
P
Antolini
L
L
D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000494:pharmacology*; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000494:pharmacology; D007093:Imidazoles / Q000138:chemical synthesis / Q000494:pharmacology* / Q000633:toxicity; D015394:Molecular Structure; D009152:Mutagenicity Tests; D009153:Mutagens / Q000138:chemical synthesis / Q000633:toxicity
D000890:Anti-Infective Agents; D000935:Antifungal Agents; D007093:Imidazoles; D009153:Mutagens