Galactorrhoea and amenorrhoea due to an intradural neurinoma originating from a thoracic intercostal nerve radicle.
A 42-year-old woman had galactorrhoea and amenorrhoea. Four years previously she complained of sensory disturbance of her legs, with galt disturbance. Serum PRL level was 1408 mU/l. Magnetic resonance imaging showed a spindle-shaped mass in the spinal canal at the level of the ninth thoracic vertebra. The tumour was removed and histologically was found to be a neurinoma originating from the right ninth intercostal nerve radicle. Soon after the operation, galactorrhoea, amenorrhoea and neurological symptoms disappeared. Prolactin levels normalized at 346 mU/l. These findings indicate that hyperprolactinaemia occurred as a result of the stimulation of afferent fibres from an intercostal nerve in a patient with intradural neurinoma of the intercostal nerve radicle.
Katsuren
E
E
Department of Medicine, Jichi Medical School, Tochigi, Japan.
Ishikawa
S
S
Honda
K
K
Saito
T
T
D000328:Adult; D000568:Amenorrhea / Q000209:etiology*; D005260:Female; D005687:Galactorrhea / Q000209:etiology*; D006801:Humans; D007367:Intercostal Nerves; D008279:Magnetic Resonance Imaging; D009442:Neurilemmoma / Q000150:complications*; D010524:Peripheral Nervous System Neoplasms / Q000150:complications*; D013120:Spinal Cord Neoplasms / Q000150:complications*