title: Antisense oligonucleotide inhibitors of isozymes of protein kinase C: in vitro and in vivo activity, and clinical development as anti-cancer therapeutics.
authors.affiliation: ISIS Pharmaceuticals, Carlsbad CA 92008, USA.
authors.forename: K
authors.initials: K
authors.lastname: McGraw
authors.forename: R
authors.initials: R
authors.lastname: McKay
authors.forename: L
authors.initials: L
authors.lastname: Miraglia
authors.forename: R T
authors.initials: RT
authors.lastname: Boggs
authors.forename: J P
authors.initials: JP
authors.lastname: Pribble
authors.forename: M
authors.initials: M
authors.lastname: Muller
authors.forename: T
authors.initials: T
authors.lastname: Geiger
authors.forename: D
authors.initials: D
authors.lastname: Fabbro
authors.forename: N M
authors.initials: NM
authors.lastname: Dean
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D007527:Isoenzymes / Q000037:antagonists & inhibitors* / Q000378:metabolism; D009369:Neoplasms / Q000188:drug therapy* / Q000201:enzymology; D016376:Oligonucleotides, Antisense / Q000494:pharmacology*; D011493:Protein Kinase C / Q000037:antagonists & inhibitors* / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents; D004791:Enzyme Inhibitors; D007527:Isoenzymes; D016376:Oligonucleotides, Antisense; D011493:Protein Kinase C