Dihydropyrimidine dehydrogenase deficiency: a potential etiology for 5-fluorouracil-induced neurotoxicity.
Risso
M E
ME
School of Pharmacy, University of the Pacific, Stockton, California 94037, USA.
Hasson
N K
NK
Lum
B L
BL
D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D042943:Dihydrouracil Dehydrogenase (NADP); D005472:Fluorouracil / Q000009:adverse effects*; D006801:Humans; D009422:Nervous System Diseases / Q000139:chemically induced*; D010088:Oxidoreductases / Q000172:deficiency*
D000964:Antimetabolites, Antineoplastic; D010088:Oxidoreductases; D042943:Dihydrouracil Dehydrogenase (NADP); D005472:Fluorouracil