[A comparative study of Coxiella burnetii strains differing in virulence in the intratracheal infection of guinea pigs].
As found out in earlier investigations, after the intratracheal infection of guinea pigs with C. burnetii (the method of infection, most similar to aerogenic infection which is characteristic of Coxiella under natural conditions) the maximum amount of the infective agent is accumulated in the lungs of the animals, damaging the organs of the reticuloendothelial system. The present investigation has revealed that this method of infection makes it possible differentiate C. burnetii virulent strains, differing in the level of the accumulation of the infective agent in the lungs of guinea pigs.
Suvorova
T A
TA
Pshenichnov
V A
VA
Grabarev
P A
PA
D000818:Animals; D016997:Coxiella burnetii / Q000302:isolation & purification / Q000472:pathogenicity*; D006168:Guinea Pigs; D008168:Lung / Q000382:microbiology; D008198:Lymph Nodes / Q000382:microbiology; D011778:Q Fever / Q000382:microbiology*; D051381:Rats; D013154:Spleen / Q000382:microbiology; D013997:Time Factors; D014132:Trachea; D014774:Virulence
Sravnitel'noe izuchenie razlichaiushchikhsia po virulentnosti shtammov Coxiella burnetii pri intratrakheal'nom infitsirovanii morskikh svinok.