title: Female genital tract malignancies during puberty. Uterine and cervical malignancies.
abstract: Malignancies of the uterine corpus are extremely rare. Diagnostic and therapeutic procedures should be performed according to oncological principles with individually adapted treatment regimes. Clinical cancer of the cervix is rare in adolescence; the treatment is radical surgery. Preclinical stages, that is, CIN III (severe dysplasia, carcinoma in situ) and microinvasive cancer (stages Ia1, Ia2), are important, also because of their frequency. Diagnosis is based on colposcopy, cytology, direct biopsy, histological examination, and conization. In addition, virology (HPV) and DNA cytometry may become prognostic factors. Treatment consists of conization with an exact histological examination in serial sections as a basis for preserving the uterus. The sarcoma botryoides is localized in the cervix in adolescence, whereas it is in the vagina in infants and children.
authors.affiliation: Department of Obstetrics and Gynecology, University of Graz, Austria.
authors.forename: G
authors.initials: G
authors.lastname: Tscherne
mesh_terms: D000293:Adolescent; D002648:Child; D016889:Endometrial Neoplasms / Q000175:diagnosis / Q000628:therapy; D005260:Female; D006801:Humans; D011627:Puberty; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis / Q000628:therapy; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*