title: Docetaxel-induced subungual hemorrhage.
abstract: Docetaxel (RP 56976 or Taxotere), a semisynthetic drug belonging to the family of taxoids, is a new chemotherapeutic agent used in phase II trials for breast, ovarian and lung cancer. We report 2 cases of subungual hemorrhages, which, to our knowledge, have yet to be cited in association with the use of docetaxel. Although not incapacitating, the patient should be made aware of the potential risk of this drug reaction.
authors.affiliation: Department of Dermatology and Venereology, Saínte Elisabeth Hospital, Namur, Belgium.
authors.forename: O
authors.initials: O
authors.lastname: Vanhooteghem
authors.forename: J
authors.initials: J
authors.lastname: André
authors.forename: A
authors.initials: A
authors.lastname: Vindevoghel
authors.forename: L
authors.initials: L
authors.lastname: Vandenbossche
authors.forename: A
authors.initials: A
authors.lastname: Vandeveire
authors.forename: M
authors.initials: M
authors.lastname: Song
mesh_terms: D000328:Adult; D000972:Antineoplastic Agents, Phytogenic / Q000009:adverse effects* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy; D018567:Breast Neoplasms, Male / Q000188:drug therapy; D000077143:Docetaxel; D005260:Female; D006470:Hemorrhage / Q000139:chemically induced*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009260:Nail Diseases / Q000139:chemically induced*; D017239:Paclitaxel / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D043823:Taxoids
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D043823:Taxoids; D000077143:Docetaxel; D017239:Paclitaxel