title: [Lyme disease in Mato Grosso do Sul State, Brazil: report of three clinical cases, including the first of Lyme meningitis in Brazil].
abstract: The authors report the occurrence of the first three clinical cases of Lyme disease in Mato Grosso do Sul State, including the first case of Lyme meningitis in Brazil. These were identified by clinical and laboratorial criteria. Anti-Borrelia burgdorferi antibody search was carried out through ELISA and Western Blotting techniques, the former providing identification of IgG class antibodies alone, in one only of those cases. Through Immunoblotting, the following features were found in serum: 5 IgG and 2 IgM bands for the first case; 7 IgG and 2 IgM bands for the second; and 5 IgG and 6 IgM bands for the third. In the latter, presence fo specific antibodies was searched in liquor, due to lymphomonocitary meningitis occurrence, and one IgM band was detected. After antibiotic therapy, all patients exhibited significant clinical and laboratorial improvement in their conditions along with symptom regression to the present moment.
authors.affiliation: Disciplina de Reumatologia, Faculdade de Medicina, Universidade de São Paulo.
authors.forename: I P
authors.initials: IP
authors.lastname: Costa
authors.forename: N H
authors.initials: NH
authors.lastname: Yoshinari
authors.forename: P J
authors.initials: PJ
authors.lastname: Barros
authors.forename: V L
authors.initials: VL
authors.lastname: Bonoldi
authors.forename: E P
authors.initials: EP
authors.lastname: Leon
authors.forename: A D
authors.initials: AD
authors.lastname: Zeitune
authors.forename: W
authors.initials: W
authors.lastname: Cossermelli
mesh_terms: D000293:Adolescent; D000328:Adult; D001899:Borrelia Infections / Q000175:diagnosis* / Q000188:drug therapy; D001938:Brazil; D005260:Female; D006801:Humans; D008193:Lyme Disease / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D016920:Meningitis, Bacterial / Q000175:diagnosis* / Q000188:drug therapy
vernacular_title: Doença de Lyme em Mato Grosso do Sul: relato de três casos clínicos, incluindo o primeiro relato de meningite de Lyme no Brasil.