title: HIV immunopathogenesis.
abstract: The challenges of human immunodeficiency virus type 1 (HIV-1) infection are related to the evolving scientific knowledge that has accumulated regarding the pathogenesis of the HIV illness trajectory. HIV-1 infection results in the clinical presentation of a disease process that encompasses a spectrum of illness from asymptomatic infection to acquired immune deficiency syndrome (AIDS). This article will provide a review of the human immune system, the structure, life cycle, and kinetics of HIV including its effects on the immune system, as well as the transmission, diagnosis, and current treatment recommendations.
authors.affiliation: Delta Region AIDS Education and Training Center, Louisiana State University Medical Center, USA.
authors.forename: C
authors.initials: C
authors.lastname: Brennan
authors.forename: D J
authors.initials: DJ
authors.lastname: Porche
mesh_terms: D018450:Disease Progression; D015658:HIV Infections / Q000175:diagnosis / Q000276:immunology* / Q000451:nursing / Q000628:therapy / Q000635:transmission; D015497:HIV-1 / Q000254:growth & development / Q000472:pathogenicity; D006801:Humans; D007107:Immune System / Q000502:physiology