title: [Clinical efficacy of three-dimensional chemical shift imaging (3D-CSI)--a study of 3D-CSI in the human heart and its clinical perspectives for the future].
abstract: The main purpose of this study was to investigate whether in vivo 31P three-dimensional chemical shift imaging(3D-CSI) of the human heart could serve as a useful tool for evaluating myocardial metabolism. We performed slice-selective 3D-CSI employing nuclear magnetic resonance(NMR) imaging with slice selection in one dimension and phase encoding in two dimensions. 31P NMR images of phosphocreatine (PCr) and ATP were superimposed on a corresponding 1H image of the heart. Our study revealed that while accurate in vivo 31P 3D-CSI measurement of the human heart is difficult to achieve it is not impossible, although various additional techniques for improving signal to noise ratio are indicated.
authors.affiliation: First Department of Internal Medicine, Shiga University of Medical Science.
authors.forename: T
authors.initials: T
authors.lastname: Yabe
authors.forename: K
authors.initials: K
authors.lastname: Mitsunami
authors.forename: T
authors.initials: T
authors.lastname: Inubushi
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy; D009206:Myocardium / Q000378:metabolism*; D010725:Phosphocreatine / Q000378:metabolism; D010758:Phosphorus
chemical_list: D010725:Phosphocreatine; D010758:Phosphorus; D000255:Adenosine Triphosphate