title: Salivary fluoride content after toothbrushing with a sodium fluoride and an amine fluoride dentifrice followed by different mouthrinsing procedures.
abstract: The aim of the present study was to determine the salivary fluoride content after toothbrushing with a sodium fluoride and amine fluoride dentifrice followed by two different mouthrinsing procedures. Twenty-four dental students took part in this six-treatment, six-period study with a cross-over design. They brushed their teeth with an amine fluoride, a sodium fluoride, and a non-fluoridated dentifrice. After toothbrushing the subjects spat out the saliva/dentifrice slurry and underwent one of the following procedures: 1) mouthrinsing with 20 ml distilled water; 2) no mouthrinsing after spitting out. Whole saliva samples were collected before (baseline), 10 and 90 min after toothbrushing and mouthrinsing, respectively. Fluoride analysis was performed with a fluoride-sensitive electrode. Both dentifrices caused an elevated fluoride level in saliva after brushing. Use of the amine fluoride dentifrice resulted in higher salivary fluoride contents compared to the sodium fluoride toothpaste. However, this difference was statistically significant only 90 min after toothbrushing when preceded by mouthrinsing after brushing. Mouthrinsing with water after brushing led to significantly lower fluoride levels compared to the non-rinsing technique 10 min after brushing. Mouthrinsing after toothbrushing with fluoride dentifrices reduces the salivary fluoride concentration of both an amine and a sodium fluoride dentifrice.
authors.affiliation: University of Freiburg, Department of Operative Dentistry, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Attin
authors.forename: E
authors.initials: E
authors.lastname: Hellwig
mesh_terms: D000328:Adult; D000588:Amines; D000704:Analysis of Variance; D001682:Biological Availability; D002327:Cariostatic Agents / Q000032:analysis* / Q000493:pharmacokinetics; D018592:Cross-Over Studies; D003731:Dental Caries / Q000517:prevention & control; D003802:Dentifrices / Q000737:chemistry*; D005459:Fluorides / Q000032:analysis* / Q000493:pharmacokinetics; D006801:Humans; D009067:Mouthwashes; D012463:Saliva / Q000737:chemistry* / Q000378:metabolism; D012969:Sodium Fluoride; D018709:Statistics, Nonparametric; D013997:Time Factors; D014002:Tin Fluorides; D014099:Toothbrushing; D014867:Water
chemical_list: D000588:Amines; D002327:Cariostatic Agents; D003802:Dentifrices; D009067:Mouthwashes; D014002:Tin Fluorides; D014867:Water; C075174:amine fluoride gel; D012969:Sodium Fluoride; D005459:Fluorides