title: Synchronized Plasmodium yoelii yoelii: pattern of gametocyte production, sequestration and infectivity.
abstract: The chronobiology of the gametocytes of P. yoelii was studied in Percoll-glucose synchronized infection in the mouse. The gametocyte developmental cycle consisted of 4 successive stages: stage 0 maturation took 27 hours from merozoite invasion, stage 0 to stage 1 lasted 6 hours, stage I to stage II and stage II to stage III lasted 3 hours each. Stage 0 gametocytes were found to sequester in small peripheral capillaries, and the number of oocysts in mosquitoes was related to the number of stage 0 gametocytes ingested.
authors.affiliation: Laboratoire de Biologie Parasitaire et de Chimiothérapie, CNRS (ERS 156), Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Gautret
authors.forename: F
authors.initials: F
authors.lastname: Miltgen
authors.forename: A G
authors.initials: AG
authors.lastname: Chabaud
authors.forename: I
authors.initials: I
authors.lastname: Landau
mesh_terms: D000818:Animals; D000852:Anopheles / Q000469:parasitology; D005260:Female; D008288:Malaria / Q000469:parasitology; D008297:Male; D051379:Mice; D010967:Plasmodium yoelii / Q000166:cytology / Q000254:growth & development* / Q000302:isolation & purification / Q000502:physiology; D013997:Time Factors