title: Moving actuator type total artificial heart with reverse position of the aortic and pulmonary conduits.
abstract: Adequate intrathoracic anatomical compatibility is one of the most important considerations in designing a fully implantable total artificial heart (TAH). We have recently developed an innovative concept of reverse positioning of the aortic and pulmonary conduits to facilitate anatomical compatibility of the moving actuator type TAH. The pulmonary conduit of this TAH is designed to be located posterior to the aortic conduit, which results in a substantial reduction in the anteroposterior diameter of this heart, as well as the virtual elimination of the compression of the low pressure pulmonary conduit. In ovine orthotopic implantation experiments with this model of the TAH, we consecutively achieved 3 day survival in 1 sheep and 2 day survival in another. To the best of our knowledge, these were the first significant short-term survival cases in the orthotopic implantation of electric TAHs in sheep.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Yungeun-Dong, Korea.
authors.forename: W G
authors.initials: WG
authors.lastname: Kim
authors.forename: J K
authors.initials: JK
authors.lastname: Chang
authors.forename: H C
authors.initials: HC
authors.lastname: Kim
authors.forename: B G
authors.initials: BG
authors.lastname: Min
authors.forename: Y S
authors.initials: YS
authors.lastname: Won
authors.forename: J R
authors.initials: JR
authors.lastname: Rho
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000592:standards; D001783:Blood Flow Velocity / Q000502:physiology; D004867:Equipment Design; D005260:Female; D006354:Heart, Artificial; D007723:Korea; D012756:Sheep
chemical_list: D001672:Biocompatible Materials