title: Translocation 1;19 in two brain tumors.
abstract: We report two-cases of brain tumors, one childhood medulloblastoma and one adult glioblastoma with an unusual chromosomal abnormality: a t(1;19)(q23;q13). We analyzed these karyotypes using fluorescence in situ hybridization (FISH) and wonder if this chromosomal aberration could represent a particular entity in these brain tumors like t(1;19) in ALL.
authors.affiliation: Cytogenetic Oncology laboratory, C. H. U. Timone, Marseilles, France.
authors.forename: A M
authors.initials: AM
authors.lastname: Vagner-Capodano
authors.forename: F
authors.initials: F
authors.lastname: Mugneret
authors.forename: H
authors.initials: H
authors.lastname: Zattara-Cannoni
authors.forename: J
authors.initials: J
authors.lastname: Gabert
authors.forename: B
authors.initials: B
authors.lastname: Favre
authors.forename: D
authors.initials: D
authors.lastname: Figarella-Branger
authors.forename: J C
authors.initials: JC
authors.lastname: Gentet
authors.forename: G
authors.initials: G
authors.lastname: Lena
authors.forename: J L
authors.initials: JL
authors.lastname: Bernard
mesh_terms: D001932:Brain Neoplasms / Q000235:genetics*; D002675:Child, Preschool; D002878:Chromosomes, Human, Pair 1 / Q000235:genetics; D002888:Chromosomes, Human, Pair 19 / Q000235:genetics; D005260:Female; D005909:Glioblastoma / Q000235:genetics*; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D008527:Medulloblastoma / Q000235:genetics*; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D014178:Translocation, Genetic