[Mortality in adults with asthma. Results from the Osterbro study].
A prospective analysis of overall and cause-specific mortality in subjects with self-reported asthma was undertaken using the data from The Copenhagen City Heart Study. A sample of 13,540 individuals selected from the general population was followed for 17 years. Survival of subjects with self-reported asthma was significantly poorer than that of non-asthmatics, the excess mortality being limited to pulmonary mortality. After statistical adjustment for age, length of school education, and smoking, women with asthma had a 1.7 higher risk of dying than women without asthma. The similar risk for men was 1.5. Inclusion of one-second forced expiratory volume, in % predicted, in the mortality analyses showed that the increased risk of death associated with asthma was mediated mainly through reduced lung function. We conclude that in the general population self-reported asthma is associated with a slight excess of mortality, mainly due to respiratory disease.
Lange
P
P
Epidemiologisk forskningsenhed, afdeling 7121, H:S Rigshospitalet, Osterbroundersøgelsen.
Ulrik
C S
CS
Vestbo
J
J
D000328:Adult; D000368:Aged; D001249:Asthma / Q000175:diagnosis / Q000401:mortality* / Q000503:physiopathology; D002423:Cause of Death; D003718:Denmark / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012959:Socioeconomic Factors; D014504:Urban Health
Dødelighed hos voksne med astma. Resultater fra Osterbroundersøgelsen.