Polyangiitis overlap syndrome.
A 33-year-old man was admitted to our hospital because of intermittent claudication and finger tip ulceration with a skin rash on the upper and lower extremities. He later developed a massive melena. Angiography revealed arterial occlusion in the hand and foot, skin biopsy showed vasculitis with eosinophilic infiltration, and biopsy of the colon showed mucosal vasculitis with thrombosis. A diagnosis of polyangiitis overlap syndrome was made, and all these symptoms improved after corticosteroid therapy.
Shimizu
T
T
First Department of Internal Medicine, Kansai Medical University, Moriguchi, Osaka.
Kagawa
H
H
Katsura
K
K
Shirai
K
K
Yamanaka
Y
Y
Kishimoto
Y
Y
Okamura
A
A
Fukuhara
S
S
D000328:Adult; D000792:Angiography; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging / Q000209:etiology; D006471:Gastrointestinal Hemorrhage / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007866:Leg / Q000098:blood supply / Q000000981:diagnostic imaging; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use; D013577:Syndrome; D014657:Vasculitis / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology
D007166:Immunosuppressive Agents; D011239:Prednisolone