Case-control study of risk factors for complicated eclampsia.
OBJECTIVE
To identify risk factors associated with complicated eclampsia.


METHODS
Twenty-four patients with eclampsia complicated by intracerebral hemorrhage, pulmonary edema, renal, hepatic, or respiratory failure, disseminated intravascular coagulation, abruptio placentae, pulmonary aspiration, or hemolysis, elevated liver enzymes, low platelets syndrome were compared retrospectively with 101 uncomplicated eclamptic controls. Information on maternal demographic factors, medical and obstetric histories, and maternal and perinatal outcomes was retrieved and analyzed by univariate and multivariate analysis.


RESULTS
By multiple logistic regression, the only risk factors associated with the development of complicated eclampsia were maternal age over 26 years (adjusted odds ratio [OR] 6.3, 95% confidence interval [CI] 2.17, 18.48), multiparity (adjusted OR 4.5, 95% CI 1.55, 13.60) and no prenatal care (adjusted OR 3.3, 95% CI 1.25, 9.60).


CONCLUSIONS
Maternal age above 26 years, multiparity, and no prenatal care are the maternal risk factors identified for the development of complicated eclampsia.
Conde-Agudelo
A
A
Department of Obstetrics and Gynecology, Carlos Holmes Trujillo Hospital, Cali, Colombia.
Kafury-Goeta
A C
AC
D000328:Adult; D016022:Case-Control Studies; D004461:Eclampsia / Q000150:complications* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008423:Maternal Age; D010298:Parity; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology; D011295:Prenatal Care; D012189:Retrospective Studies; D012307:Risk Factors