Baboon syndrome.
An 18-month-old patient developed Baboon syndrome after oral treatment with erythromycin syrup for a sore throat. The lymphoblastic transformation test was positive for erythromycin. Prick tests were negative although the intradermal test was positive at a concentration of erythromycin of 1:10,000. The biopsy showed a perivascular lymphocytic dermatitis. Local treatment with a potent corticoid improved the lesions after 3 days. The Baboon syndrome is uncommon among children. It has a pattern similar to systemic contact dermatitis with particular features (erythema in flexural areas). In our case, the role of erythromycin was documented. However, this antibiotic remains a relatively rare allergen.
Goossens
C
C
Department of Dermatovenereology, St. Pierre, Brugmann, Belgium.
Sass
U
U
Song
M
M
D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D017449:Dermatitis, Allergic Contact / Q000209:etiology* / Q000503:physiopathology; D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000209:etiology / Q000503:physiopathology; D004917:Erythromycin / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D008297:Male; D012882:Skin Tests; D013577:Syndrome; D014069:Tonsillitis / Q000188:drug therapy
D000900:Anti-Bacterial Agents; D004917:Erythromycin