Nontuberculous mycobacterial cervical adenitis.
Granulomatous inflammation is a common finding in pathologic evaluation of surgically excised chronic lymphadenopathy in children. Confusion exists regarding diagnosis and management of these lesions. Over a 10-year period at The Children's Hospital of Philadelphia, a total of 81 children were identified with biopsy-confirmed granulomatous lesions of the head and neck, with nontuberculous mycobacteria (NTM) accounting for 67 of the cases. The typical presentation was that of a nontender mass in the cervicofacial area present for weeks to months, unresponsive to antimicrobials. All underwent surgical excision, which was curative in 54 patients; 13 children required additional procedures. This paper reviews NTM, its typical clinical presentation, difficulty in diagnosis, and the methods of treatment.
Suskind
D L
DL
Division of Otolaryngology, Children's Hospital of Philadelphia, PA 19104, USA.
Handler
S D
SD
Tom
L W
LW
Potsic
W P
WP
Wetmore
R F
RF
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006099:Granuloma / Q000382:microbiology; D006801:Humans; D007223:Infant; D008198:Lymph Nodes / Q000382:microbiology*; D008199:Lymphadenitis / Q000382:microbiology*; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D009333:Neck; D014376:Tuberculosis / Q000175:diagnosis