title: Medullary thyroid carcinoma: one component of the inherited disorder multiple endocrine neoplasia type 2A.
abstract: OBJECTIVE
  To describe and discuss the inherited syndrome multiple endocrine neoplasia (MEN) and one of its components medullary thyroid carcinoma.
  
  
  METHODS
  Published books and articles; clinical experience.
  
  
  RESULTS
  Three distinct types of MEN are known. Type 2a consists of medullary thyroid carcinoma, pheochromocytoma, and other conditions. The disorder is autosomal-dominant. Genetic counseling and screening and biochemical screening are possible. Early detection and treatment are key to successful control.
  
  
  CONCLUSIONS
  Identification of kindreds affected by this inherited disorder can result in improved detection and early treatment. The merit and value of presumptive treatment remain unclear. IMPLICATIONS FOR NURSING PRACTISE: Nursing activities encompass prediagnosis through postoperative phases. Care involves all members of the family as well as psychological care.
authors.affiliation: Seton Hall University Graduate School of Education, South Orange, NJ, USA.
authors.forename: E
authors.initials: E
authors.lastname: Giarelli
mesh_terms: D000328:Adult; D018276:Carcinoma, Medullary / Q000451:nursing* / Q000503:physiopathology / Q000517:prevention & control / Q000601:surgery; D005817:Genetic Counseling; D006801:Humans; D008297:Male; D018813:Multiple Endocrine Neoplasia Type 2a / Q000451:nursing* / Q000503:physiopathology / Q000517:prevention & control / Q000601:surgery; D009730:Nursing Assessment; D009626:Terminology as Topic; D013964:Thyroid Neoplasms / Q000451:nursing* / Q000503:physiopathology / Q000517:prevention & control / Q000601:surgery