Pemphigoid presenting as atypical excoriated prurigo: regarding 11 cases.
The acquisition of bullous pemphigoid may have different aspects. The disease can be initiated via the development of an excoriated prurigo in which clinical and histological features do not initially suggest the diagnosis of pemphigoid. The presence of eosinophils, oedema or a cleft at the dermis-epidermis junction are not constant features of the histopathological picture. Distinguishing a bullous pemphigoid from a prurigo can only be achieved by direct immunofluorescence.
Gengoux
P
P
Unit of Dermato-Allergology and Dermato-Immunology, Louvain University, Brussels, Belgium.
Lachapelle
J M
JM
D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D004311:Double-Blind Method; D005260:Female; D019085:Fluorescent Antibody Technique, Direct; D006801:Humans; D008297:Male; D008875:Middle Aged; D010391:Pemphigoid, Bullous / Q000175:diagnosis / Q000473:pathology*; D011536:Prurigo / Q000175:diagnosis / Q000473:pathology*; D011537:Pruritus / Q000175:diagnosis / Q000473:pathology*; D012189:Retrospective Studies