title: Giant epidermoid involving 3 cranial bones.
abstract: We describe a patient with an incidental finding of an expansile osteolytic lesion centered in the sphenoid involving 3 cranial bones-frontal, temporal, and sphenoid-and invading the brain parenchyma and orbit. Biopsy demonstrated an epidermoid. The lesion was excised through frontotemporal craniotomy. Despite the benign nature of the tumor, the epidermoid had a destructive pattern of growth. Complete resection was needed to adequately address the inflammatory mass effect of the large lesion.
authors.affiliation: Department of Ophthalmic Plastics and Orbital Surgery, Massachusetts Eye and Ear Infirmary, Boston, USA.
authors.forename: S
authors.initials: S
authors.lastname: Rumelt
authors.forename: G R
authors.initials: GR
authors.lastname: Harsh
authors.forename: P A
authors.initials: PA
authors.lastname: Rubin
mesh_terms: D000328:Adult; D001706:Biopsy; D001847:Bone Diseases / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D004814:Epidermal Cyst / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D005094:Exophthalmos / Q000175:diagnosis / Q000209:etiology / Q000601:surgery; D005500:Follow-Up Studies; D005624:Frontal Bone / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008297:Male; D013100:Sphenoid Bone / Q000000981:diagnostic imaging / Q000473:pathology*; D013701:Temporal Bone / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed