title: Pre- and post-therapy blood lymphocyte levels in IgE-negative urticaria, associated with several parasitic or fungal diseases.
abstract: 115 patients with non-immune (IgE-negative) urticaria, related to parasitic (lambliasis, oxyuriasis, ascaridiasis) or fungal (candidiasis) associations were investigated-both before and one month after specific and antihistaminic therapy-concerning different percentage levels of blood lymphocyte sets and subsets, by means of flow cytometry. Before therapy, three kinds of immune deficiency patients were obtained, one in lambliasis and oxyuriasis, the second in ascaridiasis, and the third in candidiasis, respectively. Clinical, biological and immunological recovering after therapy exhibited some differences related to the presumed non-allergic etiology, i.e. better in lambliasis and oxyuriasis and worse in ascaridiasis and candidiasis.
authors.affiliation: Faculty of Medicine, Department of Microbiology and Immunology, Craiova, Romania.
authors.forename: C
authors.initials: C
authors.lastname: Voiculescu
authors.forename: M
authors.initials: M
authors.lastname: Voiculescu
authors.forename: C
authors.initials: C
authors.lastname: Avramescu
authors.forename: E
authors.initials: E
authors.lastname: Radu
mesh_terms: D000293:Adolescent; D000328:Adult; D000871:Anthelmintics / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001198:Ascaridiasis / Q000097:blood / Q000150:complications / Q000188:drug therapy / Q000276:immunology; D002177:Candidiasis / Q000097:blood / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D003289:Convalescence; D005260:Female; D005873:Giardiasis / Q000097:blood / Q000150:complications / Q000188:drug therapy / Q000276:immunology; D006633:Histamine Antagonists / Q000627:therapeutic use; D006801:Humans; D007111:Immunity, Cellular; D007073:Immunoglobulin E / Q000097:blood; D007411:Intestinal Diseases, Parasitic / Q000097:blood / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D007654:Ketoconazole / Q000627:therapeutic use; D018655:Lymphocyte Count; D016131:Lymphocyte Subsets; D008297:Male; D010123:Oxyuriasis / Q000097:blood / Q000150:complications / Q000188:drug therapy / Q000276:immunology; D014581:Urticaria / Q000097:blood / Q000188:drug therapy / Q000209:etiology / Q000276:immunology*
chemical_list: D000871:Anthelmintics; D000935:Antifungal Agents; D000981:Antiprotozoal Agents; D006633:Histamine Antagonists; D007073:Immunoglobulin E; D007654:Ketoconazole