[Scheduled biliary surgery and antibiotic prophylaxis. Is its use always justified?].
OBJECTIVE
Evaluate the need to give prophylactic antibiotic therapy in patients that undergo elective surgery for cholelithiasis.


METHODS
Prospective study in 35 patients the underwent surgery for cholelithiasis, without infectious risk factors. All of them, the hemocultives, endotoxin and Tumor Necrosis Factor has been evaluated along the surgical process.


RESULTS
The hemocultives were in all the patients negatives. The levels of Tumor Necrosis Factor decreased along the surgical process, without modifications of endotoxin levels. There were no significant differences in either of the points of the analysis.


CONCLUSIONS
Biliary surgery in patients that undergo elective surgery for cholelithiasis, without infectious risk factors, is a clean surgery, and so, in this patients is not indicated systematically an antibiotic prophylaxis.
Blanco
J R
JR
Servicio de Medicina Interna y Enf. Infecciosas, Hospital de La Rioja.
Pérez
J L
JL
Martínez
K
K
Martínez
J L
JL
Goñi
E
E
Alvarez
A
A
Pérez
E
E
Oteo
J A
JA
D019072:Antibiotic Prophylaxis; D002769:Cholelithiasis / Q000601:surgery*; D004731:Endotoxins / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014409:Tumor Necrosis Factor-alpha / Q000032:analysis
D004731:Endotoxins; D014409:Tumor Necrosis Factor-alpha
Cirugía biliar programada y profilaxis antibiótica. Está siempre justificado su uso?