title: Genetic variation in the expression of the six hsp genes in the presence of heat shock in Drosophila melanogaster.
abstract: Genetic variation in total mRNA level of the six hsp genes (hsp22, hsp23, hsp26, hsp27, hsp70 and hsp82) in the presence of heat shock was investigated by using seventy-four second- and seventy third-chromosome lines of Drosophila melanogaster which have the same genetic background derived from a highly inbred stock. There was significant variation in all the six hsp genes for both the second- and third-chromosome lines except for the hsp22 gene of the third-chromosome lines. Although all the structural genes of the heat shock proteins are localized on the third chromosome, the estimates of genetic variance for the second-chromosome lines were larger than those for the third-chromosome lines. Highly significant correlations between total mRNA level of the different hsp genes in all the combinations of the six hsp genes using the second-chromosome lines were found, but some of correlations for the third-chromosome lines were not significant. These results suggest that some second chromosome variants have similar effects on the expression of the different genes.
authors.affiliation: Division of Medical Zoology, Oita Medical University, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Otsuka
authors.forename: T S
authors.initials: TS
authors.lastname: Takano
authors.forename: T
authors.initials: T
authors.lastname: Yamazaki
mesh_terms: D000818:Animals; D002875:Chromosomes; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D005786:Gene Expression Regulation; D014644:Genetic Variation; D005828:Genetics, Population; D006360:Heat-Shock Proteins / Q000235:genetics*; D006720:Homozygote; D006358:Hot Temperature; D007178:Inbreeding; D008297:Male; D010641:Phenotype; D012333:RNA, Messenger
chemical_list: D006360:Heat-Shock Proteins; D012333:RNA, Messenger