Human immunodeficiency virus type 1 in an unusual cystic lymphoepithelial lesion of the lung.
OBJECTIVE
We present the clinical and histopathological findings of an unusual pulmonary cystic lymphoepithelial lesion in an HIV sero-positive patient.


RESULTS
The 32-year-old female patient developed two nodules in the vicinity of the right and left hila. Left upper lobectomy showed a 40-mm wide cystic lesion. The cyst wall was lined by a squamous epithelium and lymphoid tissue with a marked follicular hyperplasia and a prominent follicular cell dendritic network expressing HIV major core protein p24.


CONCLUSIONS
The absence of an Epstein-Barr virus infected lymphoid population and monoclonal immunoglobulin gene rearrangement supported the benign nature of the lesion.
Marie
B
B
Laboratoire d'Anatomie Pathologique, Hôpital Haut-Lévèque Bordeaux, France.
Labouyrie
E
E
Scheid
P
P
Siat
J
J
Ménard
O
O
Cosmidis
I
I
Plénat
F
F
Vignaud
J M
JM
D000328:Adult; D004848:Epithelium / Q000473:pathology / Q000821:virology; D005260:Female; D016655:HIV Core Protein p24 / Q000032:analysis; D015497:HIV-1 / Q000302:isolation & purification*; D006801:Humans; D008171:Lung Diseases / Q000473:pathology* / Q000821:virology; D008210:Lymphocele / Q000473:pathology* / Q000821:virology; D008221:Lymphoid Tissue / Q000473:pathology* / Q000821:virology
D016655:HIV Core Protein p24