The pedunculopontine tegmental nucleus issues collaterals to the fastigial nucleus and rostral ventrolateral reticular nucleus in the rat.
The pedunculopontine-laterodorsal tegmental nuclear complex was identified as a major source of brainstem afferents terminating in the fastigial cerebellar nucleus and/or ventrolateral reticular nucleus (n.Rvl). Collaterals from the pedunculopontine nucleus (Ch5 area) to rostral [vasopressor] regions of the fastigial nucleus and ventral reticular formation were revealed with a combined retrograde tracing technique. The data implicate acetylcholine as a transmitter and raise the hypothesis that the identified afferents may contribute to the autonomic and behavioral responses to midline cerebellar stimulation.
Ruggiero
D A
DA
Department of Neurology and Neuroscience, Cornell University Medical College, New York, NY 10021, USA.
Anwar
M
M
Golanov
E V
EV
Reis
D J
DJ
D000344:Afferent Pathways / Q000033:anatomy & histology*; D000818:Animals; D002531:Cerebellum / Q000033:anatomy & histology*; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D012154:Reticular Formation / Q000033:anatomy & histology*; D013681:Tegmentum Mesencephali / Q000033:anatomy & histology*