title: Venous haemodynamics in both legs after total knee replacement.
abstract: We studied the effect of total knee replacement on venous flow in 110 patients. Resting venous blood flow was measured using strain-gauge plethysmography before operation, after surgery and after discharge from hospital. There was a significant reduction in mean venous capacitance (p < 0.001) and mean venous outflow (p < 0.004) affecting only the operated leg. Both improved significantly after mobilisation in the early postoperative period, returning to preoperative levels by six days after surgery and before discharge from hospital. Our findings showed that venous stasis may contribute to deep-vein thrombosis only in the first few days after total knee replacement. This would be the most important period for the use of flow-enhancing prophylactic devices. Comparison with changes in blood flow after total hip replacement identified different patterns of altered haemodynamics suggesting that there are different mechanisms of venous stasis and thrombogenesis in hip and knee arthritis and during surgery for these conditions.
authors.affiliation: Department of Orthopaedic Surgery, The Queen's University of Belfast, Musgrave Park Hospital, Belfast, Northern Ireland.
authors.forename: M A
authors.initials: MA
authors.lastname: McNally
authors.forename: R
authors.initials: R
authors.lastname: Bahadur
authors.forename: E A
authors.initials: EA
authors.lastname: Cooke
authors.forename: R A
authors.initials: RA
authors.lastname: Mollan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007720:Knee Prosthesis; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D010991:Plethysmography; D011184:Postoperative Period; D012039:Regional Blood Flow