title: Antiandrogen and hormonal treatment of acne.
abstract: In the treatment of acne in women, the use of antiandrogens and other hormonal approaches is a valuable alternative to standard therapy. These treatments that are based on physiologically sound principles produce gratifying results in selected women with acne, and are the primary treatment for women with hirsutism. The drugs discussed in this article include spironolactone, cyproterone acetate, flutamide, oral contraceptives, corticosteroids, finasteride, and gonadotropin-releasing hormone agonists. Patient selection, pretreatment evaluation, and case studies also are discussed with an emphasis on practical applications.
authors.affiliation: Department of Dermatology, Oregon Health Sciences University, Portland, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Shaw
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy*; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000726:Androgen Antagonists / Q000627:therapeutic use*; D042944:Cholestenone 5 alpha-Reductase; D003276:Contraceptives, Oral / Q000627:therapeutic use; D005260:Female; D006801:Humans; D010088:Oxidoreductases / Q000037:antagonists & inhibitors; D018579:Patient Selection; D012008:Recurrence
chemical_list: D000305:Adrenal Cortex Hormones; D000726:Androgen Antagonists; D003276:Contraceptives, Oral; D010088:Oxidoreductases; D042944:Cholestenone 5 alpha-Reductase