Synthesis of new 2-arylidene-2H-1,4-benzoxazin-3(4H)-ones.
A number of 2-arylidene-2H-1,4-benzoxazin-3(4H)-ones were synthesized and evaluated for CNS activity. Some of the tested compounds exhibited marked CNS depressant activity in mice.
Gezginci
H
H
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Istanbul, Turkey.
Salman
S
S
Okyar
A
A
Baktir
G
G
D000818:Animals; D002492:Central Nervous System Depressants / Q000138:chemical synthesis / Q000494:pharmacology; D051379:Mice; D015394:Molecular Structure; D009043:Motor Activity / Q000187:drug effects; D010078:Oxazines / Q000138:chemical synthesis / Q000494:pharmacology*
D002492:Central Nervous System Depressants; D010078:Oxazines