Cytology. A valuable tool in prognostication of carcinoma breast.
Sixty consecutive cases of carcinoma breast diagnosed on fine needle aspiration cytology (FNAC) between July 1993 to June 1994 were studied prospectively. Nuclear grading was done on all cytologic smears, histologic grading was possible in only 22 cases. A good correlation was seen between nuclear grading on cytology and histology. Silver staining for nucleolar organizer region, and immunocytochemical staining for Ki-67 and C-erbB-2 could be done with ease on cytologic smears, providing necessary additional information on which to base the theraputic decisions.
Singh
U R
UR
Department of Pathology, University College of Medical Sciences, Delhi, India.
Sinha
S K
SK
Bhatia
A
A
Gupta
S
S
D001707:Biopsy, Needle; D001941:Breast Diseases / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology*; D002277:Carcinoma / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D019394:Ki-67 Antigen / Q000032:analysis; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000473:pathology; D009697:Nucleolus Organizer Region / Q000737:chemistry; D011379:Prognosis; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000032:analysis; D016622:Silver Staining
D019394:Ki-67 Antigen; D018719:Erb-b2 Receptor Tyrosine Kinases