[Prognostic value of a positive single ultrasound-guided prostatic biopsy regarding tumor volume and intracapsular nature of prostatic adenocarcinoma].
OBJECTIVE
Study of the value of a single positive prostatic biopsy in the staging of prostatic carcinoma and the significance of the tumour volume.


METHODS
The clinical, laboratory and pathological parameters were studied in 27 prostatectomized patients with a single positive prostatic biopsy.


RESULTS
The length of tumour invasion on the biopsy was 2.6 mm (evaluation on 25 biopsies). Six patients (23%) had an extracapsular tumour and 21 (78%) had a significant tumour volume. Among the 16 patients with a length of tumour invasion < or = 3 mm, 13 (81%) had a significant tumour volume. 25% of patients with less than 3 mm of invasion on the biopsy and a Gleason score < or = 6 and 12% of patients with less than 3 mm of invasion and a PSA < or = 10 ng/ml had a non-significant tumour volume.


CONCLUSIONS
The presence of a single positive prostatic biopsy is not sufficient to determine the pathological stage of a prostatic carcinoma. In this retrospective study, the majority of patients with a single positive biopsy had a significant tumour volume > 0.5 cc. No preoperative predictive factor of tumour volume was demonstrated.
Barthelemy
Y
Y
Service d'Urologie, Hôpital Henri Mondor, Créteil, France.
Gasman
D
D
Bellot
J
J
Chopin
D
D
Abbou
C C
CC
D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000473:pathology*; D000368:Aged; D001706:Biopsy / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011237:Predictive Value of Tests; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D014463:Ultrasonography
Valeur pronostique d'une unique biopsie prostatique échoguidée positive sur le volume tumoral et le caractère intracapsulaire de l'adénocarcinome prostatique.