title: Fluconazole for treatment of fungal infections of the urinary tract in children.
abstract: Two children with fungal urinary tract infections (UTI) were treated with fluconazole. One had bilateral megaureters, an almost non-functioning right kidney, and a moderately functioning left kidney because of severe vesicoureteric reflux. He underwent a ureteric reimplantation procedure but developed a fungal UTI postoperatively. The other child had bilateral refluxing megaureters, one of which appeared to open ectopically into the urethra. He acquired a fungal infection during intensive and prolonged antibiotic therapy for a bacterial UTI and septicaemia in the neonatal period. Both fungal infections were cured successfully. We recommend fluconazole as a safe and effective antifungal agent that may be used as a drug of choice for this difficult problem.
authors.affiliation: Department of Paediatric Urology, The Children's Hospital and The Institute of Child Health, Lahore, Pakistan.
authors.forename: M
authors.initials: M
authors.lastname: Zia-ul-Miraj
authors.forename: I
authors.initials: I
authors.lastname: Mirza
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009181:Mycoses / Q000188:drug therapy*; D014552:Urinary Tract Infections / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole