title: Three-dimensional structures and contexts associated with recurrent amino acid sequence patterns.
abstract: We have used cluster analysis to identify recurring sequence patterns that transcend protein family boundaries. A subset of these patterns occur predominantly in a single type of local structure in proteins. Here we characterize the three-dimensional structures and contexts in which these sequence patterns occur, with particular attention to the interactions responsible for their structural selectivity.
authors.affiliation: Graduate Group in Biophysics, University of California San Francisco School of Medicine 94143-0448, USA.
authors.forename: K F
authors.initials: KF
authors.lastname: Han
authors.forename: C
authors.initials: C
authors.lastname: Bystroff
authors.forename: D
authors.initials: D
authors.lastname: Baker
mesh_terms: D000465:Algorithms; D000595:Amino Acid Sequence; D016000:Cluster Analysis; D016208:Databases, Factual; D010363:Pattern Recognition, Automated; D011487:Protein Conformation; D016415:Sequence Alignment