title: Light and electron microscopic immunocytochemical visualization of 5-HT1B receptors in the rat brain.
abstract: Specific antipeptide antibodies were used for the immunohistochemical visualization of 5-HT1B receptors in the rat brain. A dense, specific 5-HT1B receptor-like immunoreactivity was found in the globus pallidus, the dorsal subiculum and the substantia nigra. At the light microscope level, immunostaining was diffuse within the neuropil but absent from cell bodies. Observations at the electron microscope level in the substantia nigra showed immunoperoxidase staining in fine unmyelinated axons and nerve terminals.
authors.affiliation: Département de Neurobiologie des Signaux Intercellulaires, Institut des Neurosciences, CNRS URA 1488, Université Pierre et Marie Curie, Paris, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Sari
authors.forename: K
authors.initials: K
authors.lastname: Lefèvre
authors.forename: M
authors.initials: M
authors.lastname: Bancila
authors.forename: M
authors.initials: M
authors.lastname: Quignon
authors.forename: M C
authors.initials: MC
authors.lastname: Miquel
authors.forename: X
authors.initials: X
authors.lastname: Langlois
authors.forename: M
authors.initials: M
authors.lastname: Hamon
authors.forename: D
authors.initials: D
authors.lastname: Vergé
mesh_terms: D000818:Animals; D001921:Brain / Q000033:anatomy & histology / Q000378:metabolism*; D007150:Immunohistochemistry; D008297:Male; D008854:Microscopy, Electron; D051381:Rats; D017208:Rats, Wistar; D011985:Receptors, Serotonin / Q000648:ultrastructure*; D013378:Substantia Nigra / Q000648:ultrastructure
chemical_list: D011985:Receptors, Serotonin