title: [The expression of Bordetella pertussis protective antigens during bacterial multiplication on a medium with a fixed chemical composition].
abstract: The possibility of obtaining native pertussis preparations with high immunobiological activity has been shown. To obtain such preparations, the use of B. pertussis selected strain, its growth under the conditions of static cultivation in a synthetic culture medium and the use of supernatants with the maximum content of protective antigens with the aim of obtaining protective complexes are necessary.
authors.forename: E I
authors.initials: EI
authors.lastname: Shmeleva
authors.forename: N U
authors.initials: NU
authors.lastname: Mertsalova
authors.forename: E V
authors.initials: EV
authors.lastname: Sukhinova
authors.forename: G A
authors.initials: GA
authors.lastname: Kirillova
authors.forename: T N
authors.initials: TN
authors.lastname: Remova
authors.forename: I G
authors.initials: IG
authors.lastname: Bazhanova
authors.forename: M N
authors.initials: MN
authors.lastname: Ozeretskovskaia
authors.forename: M V
authors.initials: MV
authors.lastname: Britsina
authors.forename: E V
authors.initials: EV
authors.lastname: Ermolova
authors.forename: N S
authors.initials: NS
authors.lastname: Zakharova
mesh_terms: D000818:Animals; D000942:Antigens, Bacterial / Q000096:biosynthesis* / Q000276:immunology / Q000302:isolation & purification; D001431:Bacteriological Techniques; D001886:Bordetella pertussis / Q000254:growth & development / Q000276:immunology*; D003470:Culture Media; D007114:Immunization; D007962:Leukocytes / Q000276:immunology; D051379:Mice; D010567:Pertussis Vaccine / Q000096:biosynthesis* / Q000276:immunology / Q000302:isolation & purification; D010566:Virulence Factors, Bordetella / Q000032:analysis
chemical_list: D000942:Antigens, Bacterial; D003470:Culture Media; D010567:Pertussis Vaccine; D010566:Virulence Factors, Bordetella
vernacular_title: Ekspressiia protektivnykh antigenov Bordetella pertussis v protsesse razmnozheniia bakteriĭ v srede opredelennogo khimicheskogo sostava.