title: Glutathione S-transferase theta genetic polymorphism might influence tacrine hepatotoxicity in Alzheimer's patients.
authors.affiliation: Clinical Pharmacology Unit, Saint Antoine University Hospital, School of Medicine Paris 6, France. christian.funck-brentano@sau.ap-hop-paris-fr
authors.forename: L
authors.initials: L
authors.lastname: Becquemont
authors.forename: S
authors.initials: S
authors.lastname: Lecoeur
authors.forename: T
authors.initials: T
authors.lastname: Simon
authors.forename: P
authors.initials: P
authors.lastname: Beaune
authors.forename: C
authors.initials: C
authors.lastname: Funck-Brentano
authors.forename: P
authors.initials: P
authors.lastname: Jaillon
mesh_terms: D000368:Aged; D000410:Alanine Transaminase / Q000097:blood; D000544:Alzheimer Disease / Q000188:drug therapy / Q000235:genetics*; D056486:Chemical and Drug Induced Liver Injury; D005838:Genotype; D005982:Glutathione Transferase / Q000235:genetics*; D006801:Humans; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic; D012307:Risk Factors; D013619:Tacrine / Q000009:adverse effects*
chemical_list: D013619:Tacrine; D005982:Glutathione Transferase; D000410:Alanine Transaminase