[Late onset of pseudobulbar paralysis and dystonia in a case of hemispheric cortical dysplasia].
The atypical clinical course of a young male with encephalopathy due to right hemispheric cortical dysplasia (pachygiria) is described. From the first months of life the course of the disease was a static encephalopathy with left hemiparesis, epilepsy and mild mental retardation. When he was 14 years old a subacute pseudobulbar palsy, dystonia and spread of the paresis to the right side occurred. Epileptic seizures, paroxysmal EEG abnormalities and drug ingestion were excluded. Neuropsychological studies showed a low level of cognitive functions, probably related to the malformative encephalopathy and expressive language deficit due to the pseudobulbar paresis. We speculate that this case could be an atypical case of delayed onset dyskiesia.
Sans
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A
Unidad integrada de Pediatria, Hospital Sant Joan de Déu-Hospital, Clinic, Barcelona, Espana.
Gassió
R
R
López-Casas
J
J
Férnandez-Alvarez
E
E
D000328:Adult; D017668:Age of Onset; D002540:Cerebral Cortex / Q000002:abnormalities*; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology; D004421:Dystonia / Q000150:complications / Q000175:diagnosis*; D007839:Functional Laterality; D006801:Humans; D007806:Language Disorders / Q000175:diagnosis / Q000209:etiology; D010243:Paralysis / Q000150:complications / Q000175:diagnosis*
Inicio tardío de parálisis pseudobulbar y distonía en un caso de displasia cortical hemisférica.