title: Barotolerance is dependent on both trehalose and heat shock protein 104 but is essentially different from thermotolerance in Saccharomyces cerevisiae.
abstract: The contribution of trehalose and hsp104 to barotolerance in Saccharomyces cerevisiae has been investigated. Mutant strains, which lacked the ability to accumulate trehalose and/or hsp104, were examined for barotolerance and thermotolerance. All the mutants showed lower barotolerance and thermotolerance than their control strains. Trehalose had a greater protective effect towards high pressure than high temperature. Thus, trehalose and hsp104 are important factors for barotolerance and thermotolerance, but trehalose is more important for barotolerance than for thermotolerance.
authors.affiliation: National Institute of Bioscience and Human Technology, Agency of Industrial Science and Technology, Ibaraki, Japan. iwahashi@nibh.go.jp
authors.forename: H
authors.initials: H
authors.lastname: Iwahashi
authors.forename: K
authors.initials: K
authors.lastname: Obuchi
authors.forename: S
authors.initials: S
authors.lastname: Fujii
authors.forename: Y
authors.initials: Y
authors.lastname: Komatsu
mesh_terms: D006360:Heat-Shock Proteins / Q000502:physiology*; D006358:Hot Temperature; D009154:Mutation; D011312:Pressure; D012441:Saccharomyces cerevisiae / Q000502:physiology*; D014199:Trehalose / Q000502:physiology*
chemical_list: D006360:Heat-Shock Proteins; D014199:Trehalose