[Experimental therapy of perforating wounds of cornea with adhelon].
The efficacy of Adhelon, a new stimulator of repair regeneration belonging to the group of adhesion factors, was experimentally assessed in the treatment of ocular injuries on a model of perforating untreated wound of the cornea. Clinical and histologic studies in two groups of rabbits persuasively demonstrated the benign effect of adhelon on the course of wound process: the period of inflammatory reaction shortened, infectious complications were prevented, the wound edges closed sooner, epithelialization and reconstruction of newly formed cicatricial tissue was accelerated. Application of adhelon led to the formation of more delicate, compact, and vessel-free cicatrices and accelerated the repair regeneration of the wounded cornea.
Gundorova
R A
RA
NII of Eye Diseases of Gelmogolts, Moscow.
Khoroshilova-Maslova
I P
IP
Chentsova
E V
EV
Ilatovskaia
L V
LV
Iamskova
V P
VP
Romanova
I I
II
D000269:Adhesives / Q000008:administration & dosage / Q000627:therapeutic use*; D000287:Administration, Topical; D000818:Animals; D002682:Chinchilla; D003315:Cornea / Q000187:drug effects / Q000473:pathology; D065306:Corneal Injuries; D015807:Eye Injuries, Penetrating / Q000188:drug therapy* / Q000473:pathology; D011817:Rabbits; D014945:Wound Healing / Q000187:drug effects
D000269:Adhesives
Primenenie Adgelona v lechenii pronikaiushchikh raneniĭ rogovitsy v eksperimente.