title: [A patient with acromegalic heart disease--a case report].
abstract: A perioperative anesthetic management of a 69 year old woman with acromegaly whose clinical course was characterized by severe heart failure is described. The patient showed symptoms of massive cardiomegaly. Endocrine studies indicated that her pituitary tumor was active with hyperproduction of growth hormone. There was no demonstrable evidence for other known causes of heart disease. Following hormonal therapy using continuous subcutaneous infusion of somatostatin for about two months, there was improvement in daily activity and reduction in heart size. After the improvement of cardiac function, transsphenoidal hypophysectomy was performed under general anesthesia and its perioperative course was quite uneventful. We conclude that because cardiac involvement such as left ventricular dilatation in acromegaly might be reversible with proper treatment, any surgical procedure, as long as the case is elective, should be considered after hormone therapy.
authors.affiliation: Department of Anesthesiology, Shimane Medical University, Izumo.
authors.forename: K
authors.initials: K
authors.lastname: Hashimoto
authors.forename: M
authors.initials: M
authors.lastname: Yamanaka
authors.forename: H
authors.initials: H
authors.lastname: Uchida
authors.forename: Y
authors.initials: Y
authors.lastname: Saito
authors.forename: Y
authors.initials: Y
authors.lastname: Kosaka
mesh_terms: D000172:Acromegaly / Q000150:complications*; D000236:Adenoma / Q000150:complications / Q000601:surgery; D000368:Aged; D000768:Anesthesia, General; D002311:Cardiomyopathy, Dilated / Q000150:complications*; D005260:Female; D006801:Humans; D007016:Hypophysectomy / Q000379:methods*; D007279:Injections, Subcutaneous; D010911:Pituitary Neoplasms / Q000150:complications / Q000601:surgery; D011292:Premedication; D011300:Preoperative Care; D013004:Somatostatin / Q000008:administration & dosage
chemical_list: D013004:Somatostatin