Tumor extent of slowly progressive oligodendroglioma determined by 18F-fluorophenylalanine positron emission tomography.
We report the use of positron emission tomography (PET) and 18F-fluorophenylalanine (18F-Phe) to determine the extent of a slowly progressive oligodendroglioma, which gradually grew over 10 years after the onset of convulsions. The tumor exhibited intense accumulation of 18F-Phe and was easily distinguished from the surrounding brain tissue. The tumor lesion indicated by 18F-phe PET was more extensive than the lesion detected by computerized tomography (CT) and was comparable to the hypointense lesion detected by T2-weighted magnetic resonance imaging (MRI). The tumor, a histologically verified oligodendroglioma, was extensively resected, and its extent corresponded to the high uptake region of 18F-Phe. The accuracy of the 18F-Phe PET technique for determining the extent of a tumor is valuable and will aid in the selection of an appropriate therapy modality for the management of oligodendrogliomas.
Mineura
K
K
Neurosurgical Service, Akita University, Japan. mineura@med.akita-u.ac.jp
Shioya
H
H
Kowada
M
M
Uemura
K
K
D001706:Biopsy; D002533:Cerebral Angiography; D005462:Fluorine Radioisotopes; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009837:Oligodendroglioma / Q000000981:diagnostic imaging* / Q000601:surgery; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed
D005462:Fluorine Radioisotopes