Asbestos bodies in bronchoalveolar lavage fluid and sputum.
The aim of the study was to determine the concordance of asbestos body (AB) detection in sputum and bronchoalveolar lavage fluid (BALF). AB were detected in the BALF of 110 former or current asbestos workers with medium weak exposure level and, for 65 subjects, in sputum. Several spontaneous sputum samples were taken from each subject. AB prevalence in BALF was rather low (48.2%) especially in subjects with former chrysotile exposure (32.5%). AB prevalence was lower in smokers (40.9%) and ex-smokers (40.7%) than in non-smokers (68.7%). In the sub-group, who underwent both sputum and BALF examination, the concordance of AB detection was observed only in 56.8% of the cases. Neither of the two methods had significant prevalence over the other but were complementary, as both are useful in increasing the probability of AB detection.
Capellaro
E
E
Department of Traumatology, Orthopaedics and Occupational Medicine, University of Turin.
Chiesa
A
A
Villari
S
S
Bontempi
S
S
Sulotto
F
F
Scansetti
G
G
D001194:Asbestos / Q000032:analysis*; D017636:Asbestos, Amphibole / Q000032:analysis; D017632:Asbestos, Serpentine / Q000032:analysis; D001195:Asbestosis / Q000175:diagnosis; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D009790:Occupations; D015995:Prevalence; D012907:Smoking / Q000009:adverse effects; D013183:Sputum / Q000737:chemistry*
D017636:Asbestos, Amphibole; D017632:Asbestos, Serpentine; D001194:Asbestos