Role of type 1 fimbriae in EPEC infections.
Several fimbriae have been implicated as potentially important in EPEC adhesion and pathogenesis. EPEC strain E2348/69 produced only bundle forming pili and type 1 fimbriae, and did not produce other accesory adhesins identified in EPEC strain B171. Cloning and mutagenesis of these EPEC fim genes indicated that type 1 pili had no affect on levels or patterns of adhesion to cultured human cells.
Elliott
S J
SJ
Center for Vaccine Development, 685, W. Baltimore St, MD, 21201, USA.
Kaper
J B
JB
D000818:Animals; D001422:Bacterial Adhesion; D003001:Cloning, Molecular; D004926:Escherichia coli / Q000235:genetics / Q000472:pathogenicity*; D010861:Fimbriae, Bacterial / Q000235:genetics / Q000502:physiology*; D006801:Humans; D016296:Mutagenesis