title: [Increased physical activity due to intermittent self-ventilation in chronic respiratory insufficiency].
abstract: BACKGROUND
  Nocturnal mechanical ventilation (NMV) can reduce symptoms of hypoventilation and improve gas exchange in patients with chronic respiratory failure but there is no data concerning the impact of nocturnal mechanical ventilation on daily activity. We prospectively measured daily activity as judged by total steps per day.
  
  
  METHODS
  Thirty stable patients (17 men, mean age 55.2 years, pCO2: 62.3 +/- 9.0 mmHg) with chronic respiratory failure.
  
  
  METHODS
  Kyphoscoliosis (n = 11), COLD (n = 7), neuromuscular diseases (n = 6), post-tbc sequelae (n = 6). Applying a pedometer over a 7 day period before and 3 months after initiating nocturnal mechanical ventilation the steps per day were counted. We also obtained arterial blood gases and applied the St. George's Respiratory Questionnaire (scoring range from 0 = complete health to 100 = worst possible).
  
  
  CONCLUSIONS
  The daily activity in patients with hypercapnic respiratory failure as judged by the total amount of steps per day increased by 120% after 3 months of nocturnal mechanical ventilation (from 1606.9 +/- 1341.3 to 3535 +/- 1813.8 steps per day, p < 0.0001). This was associated with a significant improvement in daytime blood gases and quality of life (QoL) as judged by questionnaire (total score: from 61.3 +/- 14.9 to 48.3 +/- 18.7, p = 0.0006). However no correlation between steps per day and QoL was found.
authors.affiliation: Krankenhaus Kloster Grafschaft, Zentrum fur Pneumologie, Beatmungs- und Schlafmedizin, Schmallenberg-Grafschaft.
authors.forename: B
authors.initials: B
authors.lastname: Schönhofer
authors.forename: M
authors.initials: M
authors.lastname: Geibel
authors.forename: P
authors.initials: P
authors.lastname: Jones
authors.forename: D
authors.initials: D
authors.lastname: Köhler
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007384:Intermittent Positive-Pressure Breathing; D008173:Lung Diseases, Obstructive / Q000209:etiology / Q000503:physiopathology / Q000534:rehabilitation*; D008297:Male; D008875:Middle Aged; D009551:Night Care; D010809:Physical Fitness / Q000502:physiology*; D011788:Quality of Life; D012131:Respiratory Insufficiency / Q000209:etiology / Q000503:physiopathology / Q000534:rehabilitation*; D014692:Ventilation-Perfusion Ratio / Q000502:physiology; D016138:Walking / Q000502:physiology*
vernacular_title: Zunahme der körperlichen Aktivität infolge intermittierender Selbstbeatmung bei chronisch ventilatorischer Insuffizienz.