title: [Significance of adhesion molecules in oncology].
abstract: Cell-Cell-and cell-extracellular matrix interactions are important in the process of tumor cell invasion and metastasis. These interactions are mediated by adhesion molecules e.g. CD44, integrins, E-cadherin and N-CAM. The role of adhesion molecules along metastatic cascade as well as their importance in tumor differentiation and progression are discussed herein.
authors.affiliation: Gerhard-Domagk-Institut für Pathologie, Münster.
authors.forename: H J
authors.initials: HJ
authors.lastname: Terpe
authors.forename: W
authors.initials: W
authors.lastname: Böcker
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis*; D015820:Cadherins / Q000032:analysis / Q000502:physiology; D015815:Cell Adhesion Molecules / Q000032:analysis* / Q000502:physiology; D002465:Cell Movement / Q000502:physiology; D006801:Humans; D018960:Hyaluronan Receptors / Q000032:analysis / Q000502:physiology; D016023:Integrins / Q000032:analysis / Q000502:physiology; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000473:pathology* / Q000503:physiopathology; D019006:Neural Cell Adhesion Molecules / Q000032:analysis / Q000502:physiology
chemical_list: D014408:Biomarkers, Tumor; D015820:Cadherins; D015815:Cell Adhesion Molecules; D018960:Hyaluronan Receptors; D016023:Integrins; D019006:Neural Cell Adhesion Molecules
vernacular_title: Bedeutung von Adhäsionsmolekülen in der Onkologie.