title: Lymphoma of the lumbar nerve root: case report.
abstract: BACKGROUND
  Lymphoma deposits in the spine are typically extradural. However, we report the case of a 38-year-old man who had a peripheral T-cell lymphoma with both intra- and extradural involvement.
  
  
  METHODS
  The patient presented with a 3-month history of right hip and thigh pain. Computed tomography and magnetic resonance imaging revealed features indistinguishable from those of a benign neurofibroma, except for a small area of T2-weighted signal abnormality in the third lumbar vertebral body.
  
  
  METHODS
  A solitary lesion of the right third lumbar root with normal surrounding bone and soft tissue was excised at surgery. At immunohistopathological evaluation, a diagnosis was made of peripheral lymphoma. Postoperative evaluation did not reveal lymphoma in the cerebrospinal fluid, abdomen, chest, blood, or bone marrow. This case illustrates that lymphomas can grow in patterns indistinguishable from a tumor of a nerve root. Therefore, other treatment modalities would have been considered had the diagnosis of lymphoma been made preoperatively.
  
  
  CONCLUSIONS
  Involvement of a solitary nerve root by lymphoma, although rare, should be suspected in all cases of nerve root neurofibroma, and magnetic resonance imaging should be performed. Even minor signal abnormalities in adjoining vertebrae signal the possibility of malignancy. Percutaneous biopsy of suspicious bony lesions and systemic evaluation can demonstrate other sites of involvement, enabling the confirmation of the diagnosis and appropriate treatment without recourse to surgery.
authors.affiliation: Department of Neurosurgery, Christ Hospital, University of Cincinnati College of Medicine, Ohio, USA.
authors.forename: R
authors.initials: R
authors.lastname: Viswanathan
authors.forename: N K
authors.initials: NK
authors.lastname: Swamy
authors.forename: J
authors.initials: J
authors.lastname: Vago
authors.forename: S B
authors.initials: SB
authors.lastname: Dunsker
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D006801:Humans; D007796:Laminectomy; D008161:Lumbosacral Region; D008223:Lymphoma / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D013126:Spinal Nerve Roots; D016896:Treatment Outcome