[Substantiation of MAC of crotonaldehyde in environmental air].
The reflex and resorptive effects of crotonaldehyde was studied. The maximum acceptable concentration (MAC) of crotonaldehyde was established to be 0.025 mg/m3, the mean daily MAC recommended to be 0.003 mg/m3, Hazard Class 2. It was shown that nasopharyngeal mucosal morphological changes in laboratory animals might serve as significant criteria for the action of the agent having an irritant effect.
Tepikina
L A
LA
Skvortsova
E L
EL
Shipulina
Z V
ZV
Kartashova
A V
AV
Mol'kov
Iu N
IuN
Sizova
N N
NN
D000395:Air Pollutants, Occupational / Q000633:toxicity; D000447:Aldehydes / Q000633:toxicity; D000818:Animals; D002415:Cats; D005260:Female; D008452:Maximum Allowable Concentration; D051379:Mice; D008962:Models, Theoretical; D009297:Nasal Mucosa / Q000187:drug effects; D011817:Rabbits; D051381:Rats
D000395:Air Pollutants, Occupational; D000447:Aldehydes; C012796:2-butenal
Obosnovanie PDK krotonovogo al'degida v atmosphernom vozdukhe.