Differentiation of dual seropositivity to HIV 1 and HIV 2 in Ghanaian sera using line immunoassay (INNOLIA).
Two hundred serum samples from AIDS-like patients, blood donors and miscellaneous patients were screened by ELISA for HIV 1-2. Repeatedly positive samples were confirmed using the Western Blot (WB). Twenty samples that were dual positive were further analysed by Innolia, which contains synthetic or recombinant antigens in HIV-1 and HIV-2. Only 5 of the samples were dual positive. The need for further analysis of dual WB results is re-emphasized.
Mingle
J A
JA
Department of Microbiology University of Ghana Medical School Acrra, Ghana.
D015153:Blotting, Western; D003937:Diagnosis, Differential; D004797:Enzyme-Linked Immunosorbent Assay; D005869:Ghana; D006679:HIV Seropositivity / Q000097:blood / Q000175:diagnosis* / Q000276:immunology / Q000821:virology*; D015497:HIV-1; D015498:HIV-2; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D015203:Reproducibility of Results