The gene for PEDF, a retinal growth factor is a prime candidate for retinitis pigmentosa and is tightly linked to the RP13 locus on chromosome 17p13.3.
Goliath
R
R
Department of Human Genetics, MRC Research Unit of Medical Genetics, University of Cape Town Medical School Observatory, Cape Town, South Africa.
Tombran-Tink
J
J
Rodriquez
I R
IR
Chader
G
G
Ramesar
R
R
Greenberg
J
J
D002135:Calcium-Binding Proteins / Q000235:genetics; D002874:Chromosome Mapping; D002886:Chromosomes, Human, Pair 17; D005136:Eye Proteins / Q000235:genetics; D005260:Female; D051597:Hippocalcin; D006801:Humans; D008074:Lipoproteins; D008297:Male; D009414:Nerve Growth Factors / Q000235:genetics; D009419:Nerve Tissue Proteins; D010375:Pedigree; D016133:Polymerase Chain Reaction; D018807:Polymorphism, Single-Stranded Conformational; D011506:Proteins / Q000235:genetics*; D051603:Recoverin; D012174:Retinitis Pigmentosa / Q000235:genetics*; D015843:Serpins / Q000235:genetics*; D000099174:Pigment Epithelium-Derived Factor
D002135:Calcium-Binding Proteins; D005136:Eye Proteins; D051597:Hippocalcin; D008074:Lipoproteins; D009414:Nerve Growth Factors; D009419:Nerve Tissue Proteins; D011506:Proteins; D051603:Recoverin; D015843:Serpins; D000099174:Pigment Epithelium-Derived Factor; C496731:RCVRN protein, human