title: A signaling endosome hypothesis to explain NGF actions: potential implications for neurodegeneration.
authors.affiliation: Department of Physiology, University of California, San Francisco 94143, USA.
authors.forename: E C
authors.initials: EC
authors.lastname: Beattie
authors.forename: J
authors.initials: J
authors.lastname: Zhou
authors.forename: M L
authors.initials: ML
authors.lastname: Grimes
authors.forename: N W
authors.initials: NW
authors.lastname: Bunnett
authors.forename: C L
authors.initials: CL
authors.lastname: Howe
authors.forename: W C
authors.initials: WC
authors.lastname: Mobley
mesh_terms: D000818:Animals; D001710:Biotin / Q000378:metabolism; D015152:Blotting, Northern; D015153:Blotting, Western; D002458:Cell Fractionation; D002478:Cells, Cultured; D004705:Endocytosis; D011992:Endosomes / Q000502:physiology*; D006801:Humans; D018613:Microscopy, Confocal; D009410:Nerve Degeneration / Q000502:physiology*; D009414:Nerve Growth Factors / Q000502:physiology*; D015513:Oncogene Proteins / Q000378:metabolism; D016716:PC12 Cells; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D012313:RNA / Q000096:biosynthesis; D051381:Rats; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D009414:Nerve Growth Factors; D015513:Oncogene Proteins; C065400:oncogene protein trk; D012313:RNA; D001710:Biotin; D011505:Protein-Tyrosine Kinases