title: Costs and cost-effectiveness of alternative tuberculosis management strategies in South Africa--implications for policy.
abstract: OBJECTIVE
  To conduct an economic analysis of the Hlabisa community-based directly observed therapy management strategy for tuberculosis and to project costs of three alternative strategies.
  
  
  METHODS
  Hlabisa health district, KwaZulu-Natal, South Africa.
  
  
  METHODS
  An economic analysis comparing the current tuberculosis management strategy in Hlabisa with three alternative strategies (the Hlabisa strategy prior to 1991 based on hospitalisation, the national strategy and sanatorium care) in terms of costs to both health service and patient and of cost-effectiveness.
  
  
  RESULTS
  The current Hlabisa strategy was the most cost-effective (R3799 per patient cured), compared with R98307 for the strategy used prior to 1991, R9940 for the national strategy, and R11145 for sanatorium care. Between 71% and 88% of treatment costs lie with the health service, and hospitalisation (R119 per day) is the most expensive item. Prolonged hospitalisation is extremely expensive, but community care is cheaper (community clinic visit, R28; community health worker visit, R7). The total cost of supervising a patient in the community under the current Hlabisa strategy was R503, equivalent to 4.2 days in hospital. Drug costs (R157) are equivalent to just 1.3 days in hospital.
  
  
  CONCLUSIONS
  Cost to both health service and patient can be substantially reduced by using community-based directly observed therapy for tuberculosis, a strategy that is cheap and cost-effective in Hlabisa. These findings have important national implications, supporting the goals of the new tuberculosis control programme.
authors.affiliation: Centre for Epidemiological Research in Southern Africa, Medical Research Council, Hiabisa, KwaZulu-Natal.
authors.forename: D
authors.initials: D
authors.lastname: Wilkinson
authors.forename: K
authors.initials: K
authors.lastname: Floyd
authors.forename: C F
authors.initials: CF
authors.lastname: Gilks
mesh_terms: D017281:Cost of Illness; D003362:Cost-Benefit Analysis; D017048:Health Care Costs; D006291:Health Policy; D006801:Humans; D013019:South Africa / Q000453:epidemiology; D014376:Tuberculosis / Q000191:economics* / Q000453:epidemiology / Q000628:therapy