title: Haemostatic function in coronary artery disease (CAD).
abstract: Tests to evaluate haemostatic function bleeding time (BT), prothrombin time (PT) partial thromboplastin time with kaolin (PTTK), thrombin time (TT), platelet count, platelet function tests (platelet adhesiveness and microthrombus index) and plasma fibrinogen levels were performed in 30 patients of coronary artery disease (14 myocardial infarction, 16 angina pectoris) and 20 age and sex matched controls. There was no statistically significant difference in platelet adhesiveness and mean microthrombus index in patients and controls. The BT, PT, PTTK and TT were normal in all patients and controls. Stepwise logistic regression analysis showed that plasma fibrinogen was an independent risk factor in the production of CAD.
authors.affiliation: Department of Pathology, University College of Medical Sciences & GTB Hospital, Shahdara, Delhi.
authors.forename: A
authors.initials: A
authors.lastname: Gupta
authors.forename: M
authors.initials: M
authors.lastname: Sikka
authors.forename: N
authors.initials: N
authors.lastname: Madan
authors.forename: S
authors.initials: S
authors.lastname: Dwidedi
authors.forename: U
authors.initials: U
authors.lastname: Rusia
authors.forename: S
authors.initials: S
authors.lastname: Sharma
mesh_terms: D000328:Adult; D000368:Aged; D001760:Bleeding Time; D001792:Blood Platelets / Q000502:physiology; D003327:Coronary Disease / Q000097:blood*; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010314:Partial Thromboplastin Time; D010973:Platelet Adhesiveness; D010974:Platelet Aggregation; D010976:Platelet Count; D011517:Prothrombin Time; D013918:Thrombin Time
chemical_list: D005340:Fibrinogen