Cytologic diagnosis of Ki-1 lymphoma in pleural and peritoneal effusions: a case report.
This is a report of a case of Ki-1-positive large-cell anaplastic lymphoma in an 87-year-old man diagnosed on pleural and peritoneal fluids by cytomorphologic and immunohistochemical examination. Papanicolaou-stained smears revealed many single, large neoplastic cells containing one or two nuclei with occasional multinucleated cells having a wreath-like nuclear arrangement. The tumor cells expressed Ki-1 antigen and epithelial membrane antigen. This is the first known report of Ki-1 lymphoma diagnosed initially on cytologic examination of pleural and peritoneal fluids.
Burja
I T
IT
Cytopathology Section, Veterans Administration Medical Center, Johnson City, Tennessee, USA.
Thompson
S K
SK
Brown
E J
EJ
D000368:Aged; D000369:Aged, 80 and over; D001202:Ascitic Fluid / Q000737:chemistry / Q000473:pathology*; D003581:Cytodiagnosis; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D017730:Ki-1 Antigen / Q000032:analysis; D017728:Lymphoma, Large-Cell, Anaplastic / Q000737:chemistry / Q000473:pathology*; D008297:Male; D018396:Mucin-1 / Q000032:analysis; D010996:Pleural Effusion / Q000737:chemistry / Q000473:pathology*
D017730:Ki-1 Antigen; D018396:Mucin-1