[The use of xidifon for the correction of phosphorus-calcium metabolism in patients in the terminal stage of chronic kidney failure who are on programmed hemodialysis].
Correction of impaired phosphoric-calcium metabolism was performed in 15 hemodialysis patients with terminal chronic renal failure (TCRF). For this purpose a synthetic analogue of pyrophosphoric acid xidiphone produced in Russia was used (2% aqueous solution 1 tablespoon 3 times a day 0.5 h before meal for 2-3 months). Prior to and in the course of xidiphone treatment all the patients received calcium gluconate (1 g x 3 daily), polyvitamins, on-demand digoxine. Measurements of serum concentrations of urea, potassium, sodium, total calcium, alkaline phosphatase activity demonstrated xidiphone-related normalization of serum total calcium, serum activity of alkaline phosphatase, a mild rise of sodium. The results say in favor of using xidiphone in the TCRF patients.
Konstantinova
O V
OV
Ianenko
E K
EK
Danilkov
A P
AP
Pashkin
I N
IN
D000328:Adult; D002128:Calcium Metabolism Disorders / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D002614:Chelating Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D004164:Diphosphonates / Q000009:adverse effects / Q000627:therapeutic use*; D004341:Drug Evaluation; D012968:Etidronic Acid; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000150:complications / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010760:Phosphorus Metabolism Disorders / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D006435:Renal Dialysis; D013997:Time Factors
D002614:Chelating Agents; D004164:Diphosphonates; D012968:Etidronic Acid
Primenenie ksidifona dlia korrektsii fosforno-kal'tsievogo obmena u bol'nykh s terminal'noĭ stadieĭ khronicheskoĭ pochechnoĭ nedostatochnosti, nakhodiashchikhsia na programmnom gemodialeze.