[The nature of the action of chemical substances on the activity of the microflora in soft dental deposits].
Effects of the principal mineral and mineralizing components of the saliva, nutrient organic acids (carbohydrate and some others substances' metabolites) on the activity of microflora of soft dental deposit were studied in vitro. The inhibitory effect was assessed visually from the appearance or absence of deposit coating, pH measurement, and by photo- and nephelometry. Concentrations of lactic acid and sucrose were measured. The inactivating effects of the reagents were assessed by double control: qualitative, by comparing the specimen with the optic density of the extract from aqueous suspension of the deposit, and time control, by comparing the specimen with the optic density of extracts from deposit suspensions directly after mixing with the medium. Acid medium was found to block the formation of soft dental deposit and inhibit the production of lactic acid by bacterial deposit. Hence, weakly acid gargle is recommended as an effective and physiological measure preventing cariogenic situation resultant from the intake of easily fermenting carbohydrates.
Leont'ev
V K
VK
Petrovich
Iu A
IuA
Kruglova
L N
LN
D002327:Cariostatic Agents / Q000627:therapeutic use*; D003741:Dental Deposits / Q000188:drug therapy* / Q000382:microbiology*; D003864:Depression, Chemical; D004353:Drug Evaluation, Preclinical; D006801:Humans; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D012996:Solutions
D002327:Cariostatic Agents; D012996:Solutions
O kharaktere vozdeĭstviia nekotorykh khimicheskikh veshchestv na aktivnost' mikroflory miagkogo zubnogo naleta.