title: Economic evaluation of respiratory syncytial virus infection in Canadian children: a Pediatric Investigators Collaborative Network on Infections in Canada (PICNIC) study.
abstract: OBJECTIVE
  To quantify the cost and distribution of health care resources consumed annually in management of Canadian children from birth to 4 years of age with respiratory syncytial virus (RSV) infection.
  
  
  METHODS
  Estimates of direct medical expenditures (in 1993 U.S. dollars) were collected from a prospective cohort study of hospitalized children with RSV and from national and provincial databases.
  
  
  RESULTS
  The annual cost of RSV-associated illness was almost $18 million. The largest component of direct expenditures (62%) was for inpatient care for the estimated 0.7% of all infected children ill enough to require admission. Physician fees comprised only 4% of inpatient expenses. Expenditures for ambulatory patients accounted for 38% of direct costs.
  
  
  CONCLUSIONS
  The greatest reductions in the economic cost of RSV infections will be found in interventions that reduce duration of or prevent hospital stay. Costs for management of RSV infection in children in the Canadian health care system are considerably less than charges reported in the United States.
authors.affiliation: Department of Pediatrics, Izask Walton Killam-Grace Health Centre, Halifax, Nova Scotia, Canada.
authors.forename: J M
authors.initials: JM
authors.lastname: Langley
authors.forename: E E
authors.initials: EE
authors.lastname: Wang
authors.forename: B J
authors.initials: BJ
authors.lastname: Law
authors.forename: D
authors.initials: D
authors.lastname: Stephens
authors.forename: F D
authors.initials: FD
authors.lastname: Boucher
authors.forename: S
authors.initials: S
authors.lastname: Dobson
authors.forename: J
authors.initials: J
authors.lastname: McDonald
authors.forename: N E
authors.initials: NE
authors.lastname: MacDonald
authors.forename: I
authors.initials: I
authors.lastname: Mitchell
authors.forename: J L
authors.initials: JL
authors.lastname: Robinson
mesh_terms: D000041:Absenteeism; D000328:Adult; D000553:Ambulatory Care / Q000191:economics; D001988:Bronchiolitis / Q000191:economics / Q000628:therapy / Q000821:virology; D002170:Canada; D002675:Child, Preschool; D015331:Cohort Studies; D003363:Cost Control; D017281:Cost of Illness; D004180:Direct Service Costs; D005069:Evaluation Studies as Topic; D005251:Fees, Medical; D005260:Female; D017048:Health Care Costs; D015276:Health Care Rationing; D005102:Health Expenditures; D006760:Hospitalization / Q000191:economics; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007256:Information Systems; D007902:Length of Stay / Q000191:economics; D010343:Patient Admission; D011446:Prospective Studies; D018357:Respiratory Syncytial Virus Infections / Q000191:economics* / Q000628:therapy; D012141:Respiratory Tract Infections / Q000191:economics* / Q000628:therapy; D012680:Sensitivity and Specificity; D014481:United States; D014931:Women, Working