[Prevention of infections in immunosuppressed patients: prevention of post-transfusion infections].
CMV infection is the most severe transfusion-transmitted infection in immunosuppressed patients, and must be prevented in high-risk subjects by the use of seronegative units or by the use if leucocyte-reduced units. The value of these methods has been shown in patients who are seronegative for CMV. Allotransfusions may favor bacterial infections through negative immunomodulatory effects due to leucocytes. Finally, parvovirus can induce a more severe disease in immunosuppressed patients.
Joly
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Service de Médecine Interne, Hôpital Bichat-Claude-Bernard, Paris.
D017088:AIDS-Related Opportunistic Infections / Q000517:prevention & control; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007231:Infant, Newborn; D017053:Infection Control; D011247:Pregnancy; D012307:Risk Factors; D065227:Transfusion Reaction
Prophylaxie des infections chez les immunodéprimés: prévention des infections post-transfusionnelles.