title: Percutaneous sclerotherapy of venous malformations of the head and neck using sodium tetradecyl sulphate (sotradecol).
abstract: Thirty-eight patients with venous malformations of the face, neck, and tongue underwent percutaneous sclerotherapy with direct puncture and instillation of sodium tetradecyl sulphate (Sotradecol) (33-67% solution, mixed with contrast material) into the lesions. Each patient underwent from one to seven treatment sessions (mean 2.2), followed by reconstructive surgery in three cases. Of the 34 patients who responded to the follow-up questionnaire, the late results were excellent or good in 23 patients (68%), moderate in eight, unchanged in three, and were worse in one. Compared with our previous experience of embolisation of such malformations with ethanol, the results with Sotradecol were slightly worse. There was one serious complication, unilateral loss of vision in a patient with a large malformation that extended to the orbit. In conclusion, percutaneous sclerotherapy with Sotradecol is effective treatment for venous malformations of the head and neck. Careful planning is essential to reduce the risks of the treatment.
authors.affiliation: Department of Diagnostic Radiology, Oulu University Hospital, University of Oulu, Finland.
authors.forename: T M
authors.initials: TM
authors.lastname: Siniluoto
authors.forename: P A
authors.initials: PA
authors.lastname: Svendsen
authors.forename: G M
authors.initials: GM
authors.lastname: Wikholm
authors.forename: I
authors.initials: I
authors.lastname: Fogdestam
authors.forename: S
authors.initials: S
authors.lastname: Edström
mesh_terms: D000293:Adolescent; D001165:Arteriovenous Malformations / Q000628:therapy*; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006257:Head / Q000098:blood supply*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012597:Sclerosing Solutions / Q000009:adverse effects / Q000627:therapeutic use*; D015911:Sclerotherapy; D012981:Sodium Tetradecyl Sulfate / Q000009:adverse effects / Q000627:therapeutic use*; D011795:Surveys and Questionnaires
chemical_list: D012597:Sclerosing Solutions; D012981:Sodium Tetradecyl Sulfate