Dipolar cycloadditions in solid-phase organic synthesis (SPOS).
We present a concise review of polymer-supported 1,3-dipolar cycloaddition reactions. Nitrile oxide and azomethine ylides constitute the two types of 1,3-dipoles which have been used in conjunction with solid-phase organic synthesis. These cycloaddition reactions on solid phase are generally of equal or greater efficiency than the analogous solution-phase reactions.
Kantorowski
E J
EJ
Department of Chemistry, University of California, Davis 95616, USA.
Kurth
M J
MJ
D001391:Azo Compounds / Q000737:chemistry*; D002625:Chemistry, Organic / Q000379:methods*; D009570:Nitriles / Q000737:chemistry
D001391:Azo Compounds; D009570:Nitriles