title: Ethylene oxide allergy in dialysis patients.
abstract: METHODS
  Two groups of patients undergoing long-term dialysis were studied in order to evaluate the importance of ethylene oxide (EtO) in causing allergic reactions during dialysis. The first group of 50 subjects had never shown any hypersensitivity reactions related to dialysis, whereas the second group of 20 subjects had previously complained of reactions. All the patients underwent a prick test with a standard kit of aeroallergens in order to assess the presence of atopy (in doubtful cases a RAST test was carried out with the same aeroallergens). A blood sample for the investigation of EtO specific IgE antibodies was taken from all the patients; the immunoenzymatic method was used.
  
  
  RESULTS
  Sensitivity to EtO is significantly higher in the group of patients with previous allergic reactions during dialysis (55 vs 6% in the control group).
authors.affiliation: School of Allergy and Clinical Immunology, University of Messina, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Purello D'Ambrosio
authors.forename: V
authors.initials: V
authors.lastname: Savica
authors.forename: S
authors.initials: S
authors.lastname: Gangemi
authors.forename: L
authors.initials: L
authors.lastname: Ricciardi
authors.forename: G F
authors.initials: GF
authors.lastname: Bagnato
authors.forename: D
authors.initials: D
authors.lastname: Santoro
authors.forename: S
authors.initials: S
authors.lastname: Cuzzocrea
authors.forename: G
authors.initials: G
authors.lastname: Bellinghieri
mesh_terms: D000328:Adult; D000368:Aged; D004342:Drug Hypersensitivity / Q000209:etiology*; D005027:Ethylene Oxide / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis
chemical_list: D005027:Ethylene Oxide