title: [A case of 47XYY syndrome presenting with male infertility].
abstract: A 32-year-old man was referred to our hospital for primary infertility of a 4.5-year duration. Neither character nor intelligence disorders were observed. Bilateral testes measured 16 ml each. Sperm density was 0-0.1 x 10(6)/ml on 3 separate occasions. Endocrine examinations were all within normal limits. Maturation arrest was found on testicular biopsy. Karyotyping showed 47, XYY inversion. Polymerase chain reaction revealed no deletion of the azoospermic factor (AZF) gene on the Y chromosome. This is the 6th case reported in the Japanese literature of the 47XYY syndrome presenting with male infertility.
authors.affiliation: Department of Urology, St. Marianna University School of Medicine.
authors.forename: J
authors.initials: J
authors.lastname: Murakami
authors.forename: K
authors.initials: K
authors.lastname: Baba
authors.forename: N
authors.initials: N
authors.lastname: Minagawa
authors.forename: S
authors.initials: S
authors.lastname: Kono
authors.forename: M
authors.initials: M
authors.lastname: Yajima
authors.forename: T
authors.initials: T
authors.lastname: Iwamoto
mesh_terms: D000328:Adult; D006801:Humans; D007248:Infertility, Male / Q000209:etiology* / Q000473:pathology; D007621:Karyotyping; D008297:Male; D013737:Testis / Q000473:pathology; D014997:XYY Karyotype / Q000175:diagnosis*