[Judgement criteria in treatments of advanced colorectal cancers and methods of evaluation].
Because of their bad prognosis, the effectiveness assessment of advanced cancer therapy is particularly important. A strict measurement of the treatment's benefit is necessary in order to consider its true interest objectively. The assessment of the tumor response allow an appreciation of the immediate effectiveness of the treatment on the lesions. An objective response doesn't mean that there is a survival improvement, which remains the primary aim of all treatments. Statistical methods are used so as to estimate overall survival or relapse-free arrival. Evaluating the quality of life is now essential in advanced cancer management. This is a complex, subjective and multi-dimensional concept and its evaluation requires some specific and validated instruments.
Mitry
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Service de gastro-entérologie institut Gustave-Roussy, Vellejuif.
Rougier
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P
D002986:Clinical Trials as Topic; D015179:Colorectal Neoplasms / Q000628:therapy*; D005069:Evaluation Studies as Topic; D006801:Humans; D011788:Quality of Life; D014944:World Health Organization
Critères de jugement des traitements des cancers colo-rectaux évolués et méthodes d'évaluation.