[The principle of cytokine therapy in the sepsis syndrome (a preliminary report)].
The results of using recombinant interleukin-2 from yeast for the treatment of patients with the sepsis syndrome are discussed. It is noted that there was a marked immunomodulating effect, the amount of endogenous interleukin-2 increased. The patients' state was shown to become less severe (according to the SAPS criterion), the patients felt better. A conclusion is made of the possibility in principle and expediency of using cytokines for the treatment of patients with the sepsis syndrome.
Shliapnikov
S A
SA
Bubnova
N a
Na
Eriukhin
I A
IA
D000293:Adolescent; D000328:Adult; D000368:Aged; D003422:Critical Care / Q000379:methods; D016207:Cytokines / Q000627:therapeutic use*; D004341:Drug Evaluation; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007376:Interleukin-2 / Q000627:therapeutic use; D008875:Middle Aged; D008889:Military Personnel; D011994:Recombinant Proteins / Q000627:therapeutic use; D012426:Russia; D018746:Systemic Inflammatory Response Syndrome / Q000276:immunology / Q000628:therapy*
D016207:Cytokines; D007376:Interleukin-2; D011994:Recombinant Proteins
Printsip tsitokinovoĭ terapii sepsis-sindroma (predvaritel'noe soobshchenie).