Ca2+-dependent regulation in neuronal gene expression.
Ca2+ is an important signal-transduction molecule that plays a role in many intracellular signaling pathways. Recent advances have indicated that in neurons, Ca2+-controlled signaling mechanisms cooperate in order to discriminate amongst incoming cellular inputs. Ca2+-dependent transcriptional events can thereby be made selectively responsive to bursts of synaptic activity of specific intensity or duration.
Bito
H
H
Department of Pharmacology, Kyoto University Faculty of Medicine, Sakyo-ku, Kyoto 606-01, Japan. hbito@mfour.med.kyoto-u.ac.jp
Deisseroth
K
K
Tsien
R W
RW
D000818:Animals; D002118:Calcium / Q000502:physiology*; D015870:Gene Expression / Q000235:genetics*; D006624:Hippocampus / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism* / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology
D002118:Calcium