A stochastic simulation of direct ion passage through a sodium channel.
Direct passage of alkali metal cations through a model transmembrane sodium channel is simulated by means of the Brownian dynamic technique. The Langevin version of the Brownian motion in the diffusive limit and with the finite difference equation approximation was used. Ion trajectories, single channel unidirectional ionic fluxes, average times of direct passage, as well as conductivities, were calculated. The microscopic theory of channel selectivity is presented.
Veresov
V G
VG
Institute of Photobiology, Belorussian Academy of Sciences, Minsk, Republic of Belarus.
D003198:Computer Simulation; D017136:Ion Transport; D008954:Models, Biological; D012964:Sodium / Q000378:metabolism*; D015222:Sodium Channels; D013269:Stochastic Processes
D015222:Sodium Channels; D012964:Sodium