Atypical neuroleptic malignant syndrome associated with clozapine treatment.
Clozapine is an atypical neuroleptic drug that was initially thought not to cause neuroleptic malignant syndrome (NMS). The authors report a case of NMS associated with clozapine use, developed in a patient without previous history of NMS. Considering that 13 such cases (including ours) have been reported so far, NMS should be considered in the differential diagnosis of a febrile patient treated with clozapine.
Amore
M
M
Institute of Psychiatry, University of Bologna, Italy.
Zazzeri
N
N
Berardi
D
D
D000368:Aged; D003024:Clozapine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D009459:Neuroleptic Malignant Syndrome / Q000209:etiology*
D003024:Clozapine