[Exophthalmos and cranial neuropathy as a form of presentation of Wegener's granulomatosis].
The cases of three patients with Wegener's granulomatosis presenting as exophthalmos and cranial neuropathy are reported. In the first patient's symptoms were secondary to the presence of a retro-orbital mass. In the second and third patients there was dissemination of neighboring granulomatous processes. Paranasal sinuses were involved in two patients, but clinical manifestations were evident in only one. Full remission was achieved in all three. Two patients had been received immunosuppressant therapy for inflammatory processes evaluated a posteriori in the context of Wegener's granulomatosis. The immunosuppressant treatment seems to have conditioned this unusual clinical presentation.
Campello
I
I
Servicio de Neurología, Hospital Miguel Servet, Zaragoza.
Sanjuán
F
F
Brieva
L
L
Losfablos
F
F
Hermida
I
I
Velilla
J
J
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D018906:Antineoplastic Agents, Alkylating / Q000008:administration & dosage / Q000627:therapeutic use; D001921:Brain / Q000473:pathology*; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000627:therapeutic use; D005094:Exophthalmos / Q000150:complications*; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000008:administration & dosage / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D018906:Antineoplastic Agents, Alkylating; D003520:Cyclophosphamide; D011241:Prednisone
Exoftalmos y neuropatía craneal como forma de presentación de la granulomatosis de Wegener.