title: Clinical utility of a newly developed pressure swing adsorption-type oxygen concentrator with a membrane humidifier.
abstract: The clinical utility of the newly developed pressure swing adsorption (PSA)-type oxygen concentrator with a membrane humidifier that does not require added water for humidification was evaluated in 13 patients with chronic pulmonary disease who were receiving long-term oxygen therapy. PaO2 and the relative humidity were measured when the patient breathed air and oxygen from the new device via a nasal cannula. After using the new concentrator for 5 h, the patients were asked whether they experienced dry nasal passages or a dry throat. A significant difference between the PaO2 measured while the patients breathed room air and while they breathed oxygen from the new device was observed. A significant difference was observed between the relative humidity of room air (44.7 +/- 18.6%) and that of the oxygen flow (72.7 +/- 14.8%) from the new device. None of the patients experienced dry nasal passages, dry throat, or any other adverse effects. Since this new PSA-type oxygen concentrator with a membrane humidifier supplies well-humidified nasal oxygen without water, laborious cleaning of the container and changing of the water are not necessary, and may help to improve the patient's quality of life.
authors.affiliation: Third Department of Internal Medicine, Faculty of Medicine, Tottori University, Yonago, Japan. burioka@grape.med.tottori-u.ac.jp
authors.forename: N
authors.initials: N
authors.lastname: Burioka
authors.forename: K
authors.initials: K
authors.lastname: Takano
authors.forename: E
authors.initials: E
authors.lastname: Hoshino
authors.forename: H
authors.initials: H
authors.lastname: Suyama
authors.forename: S
authors.initials: S
authors.lastname: Saito
authors.forename: T
authors.initials: T
authors.lastname: Sasaki
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004867:Equipment Design; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D006813:Humidity; D008173:Lung Diseases, Obstructive / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009330:Nebulizers and Vaporizers; D010100:Oxygen / Q000097:blood; D010102:Oxygen Inhalation Therapy / Q000295:instrumentation*
chemical_list: D010100:Oxygen