title: 2,5-Diketopiperidine derivatives as non-peptide ligands for cholecystokinin receptors.
abstract: Easily accessible 2,5-diketopiperidines have been used as templates for the construction of Trp-Phe and Trp-Asp-Phe-NH2 mimics. The cycle [L-Trp psi[COCH2]-L-Phe] analogue 1a has shown to possess significant and selective affinity for CCKA receptors.
authors.affiliation: Instituto de Química Médica (C.S.I.C.), Madrid, Spain.
authors.forename: R G
authors.initials: RG
authors.lastname: González-Muñiz
authors.forename: M J
authors.initials: MJ
authors.lastname: Domínguez
authors.forename: R
authors.initials: R
authors.lastname: Herranz
authors.forename: M T
authors.initials: MT
authors.lastname: García-López
authors.forename: S J
authors.initials: SJ
authors.lastname: Ballaz
authors.forename: A
authors.initials: A
authors.lastname: Fortuño
authors.forename: J
authors.initials: J
authors.lastname: Del Río
mesh_terms: D008024:Ligands; D015394:Molecular Structure; D010455:Peptides; D010880:Piperidines / Q000737:chemistry / Q000378:metabolism*; D011949:Receptors, Cholecystokinin / Q000378:metabolism*
chemical_list: D008024:Ligands; D010455:Peptides; D010880:Piperidines; D011949:Receptors, Cholecystokinin