title: Monochromatic microtomographic imaging of osteoporotic bone.
abstract: A monochromatic beam obtained from laboratory based instrumentation has been used for the first time to carry out a microtomographic x-ray scan of a small segment of osteoporotic bone. The resulting tomograph provides an accurate map of the x-ray linear attenuation coefficient at the characteristic energy for Cu K alpha x-rays. The bone segment was imaged in a variety of ways which are common to microtomography in order to compare the efficacy of different experimental configurations. A Si crystal monochromator was placed before the x-ray detector in order to reject radiation scattered by the sample. In addition, polychromatic scans were compared with monochromatic scans. The effects of multiple scatter can be seen upon comparison of scans with and without the second monochromator. The results indicate that beam-hardening and x-ray scattering can significantly alter an image, thereby distorting the interpretation of what is physically present in the specimen. An accurate, monochromatic tomographic scanning facility is being developed in an attempt to map meaningful physical constants for various materials.
authors.affiliation: Department of Physics, Monash University, Clayton, Victoria, Australia.
authors.forename: B J
authors.initials: BJ
authors.lastname: Kirby
authors.forename: J R
authors.initials: JR
authors.lastname: Davis
authors.forename: J A
authors.initials: JA
authors.lastname: Grant
authors.forename: M J
authors.initials: MJ
authors.lastname: Morgan
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging*; D004867:Equipment Design; D006620:Hip Fractures / Q000000981:diagnostic imaging; D006801:Humans; D010024:Osteoporosis / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed / Q000295:instrumentation*