title: Gastric adenocarcinoma and dysplasia in fundic gland polyps of a patient with attenuated adenomatous polyposis coli.
abstract: Gastric adenocarcinoma has been previously recognized as a potential complication of familial adenomatous polyposis coli (APC) and attenuated forms of APC (AAPC). This tumor has only been reported to originate from adenomatous polyps of the gastric mucosa in these clinical conditions. There have been no previous case reports of gastric adenocarcinoma arising from the more commonly found fundic gland polyps associated with AAPC or APC. We report the first definitive case of gastric adenocarcinoma arising from a hyperplastic polyp of the fundis of a patient with AAPC.
authors.affiliation: William B. and Shella Konar Center for Digestive and Liver Diseases, University of Rochester Medical Center, New York, USA.
authors.forename: A
authors.initials: A
authors.lastname: Zwick
authors.forename: M
authors.initials: M
authors.lastname: Munir
authors.forename: C K
authors.initials: CK
authors.lastname: Ryan
authors.forename: J
authors.initials: J
authors.lastname: Gian
authors.forename: R W
authors.initials: RW
authors.lastname: Burt
authors.forename: M
authors.initials: M
authors.lastname: Leppert
authors.forename: L
authors.initials: L
authors.lastname: Spirio
authors.forename: W Y
authors.initials: WY
authors.lastname: Chey
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology; D011125:Adenomatous Polyposis Coli / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D008875:Middle Aged; D011127:Polyps / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D013270:Stomach / Q000473:pathology; D013274:Stomach Neoplasms / Q000175:diagnosis / Q000209:etiology* / Q000473:pathology