Chromosomal translocation, t(1;11)(q12;p15), in an extragonadal immature teratoma.
A case of immature teratoma arising from the base of the skull is reported. The cytogenetic analysis revealed t(1;11)(q12;p15) as a sole chromosomal abnormality, suggesting that the breakpoint on chromosome 11 plays an important role in the early oncogenesis of human germ cell tumors (GCTs).
Houri
T
T
Hashimoto
N
N
Ibayashi
N
N
Mori
T
T
Fujimoto
M
M
Ueda
S
S
Abe
T
T
Inazawa
J
J
D002878:Chromosomes, Human, Pair 1 / Q000235:genetics; D002880:Chromosomes, Human, Pair 11 / Q000235:genetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000235:genetics*; D013724:Teratoma / Q000235:genetics*; D014178:Translocation, Genetic