title: Chondronecrosis of the cricoid cartilage after intubation. Two case reports.
abstract: Chondronecrosis of the cricoid cartilage is a rare complication of intubation. The records of two children were reviewed. An 8-month-old girl with myelomonocytic leukaemia developed chondronecrosis 10 days after a 2-day period of ventilation. A 4-year-old girl comatose after poisoning by the histamine antagonist, alimemazine, developed chondronecrosis after a 2-day period of intubation. The complication was suspected when extubation led to dyspnoea owing to laryngeal stridor and was confirmed by direct laryngoscopy. We review the development of the condition, the causative factors, treatment and prevention.
authors.affiliation: Département d'Anesthésie-Réanimation chirurgicale 2, Hôpital Claude Huriez, CHRU Lille, France.
authors.forename: E
authors.initials: E
authors.lastname: Wiel
authors.forename: B
authors.initials: B
authors.lastname: Vilette
authors.forename: C
authors.initials: C
authors.lastname: Solanet
authors.forename: J A
authors.initials: JA
authors.lastname: Darras
authors.forename: P
authors.initials: P
authors.lastname: Scherpereel
mesh_terms: D000982:Antipruritics / Q000506:poisoning; D002405:Catheterization, Central Venous; D002675:Child, Preschool; D003413:Cricoid Cartilage / Q000473:pathology*; D005260:Female; D006801:Humans; D007223:Infant; D007442:Intubation, Intratracheal / Q000009:adverse effects*; D015479:Leukemia, Myelomonocytic, Acute / Q000150:complications; D009336:Necrosis; D014291:Trimeprazine / Q000506:poisoning
chemical_list: D000982:Antipruritics; D014291:Trimeprazine