title: The AVID trial: evidence based or randomized control trials--is the AVID study too late? Antiarrhythmics Versus Implantable Defibrillators.
abstract: A great body of clinical evidence has been accumulated--before and without the AVID trial--showing that implantable defibrillators prolong life better than currently available antiarrhythmic drugs. With this evidence already available, we question the validity of a trial that attempted, in effect, to place a price tag on life and quality of life.
authors.forename: M E
authors.initials: ME
authors.lastname: Josephson
authors.forename: S
authors.initials: S
authors.lastname: Nisam
mesh_terms: D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use*; D001145:Arrhythmias, Cardiac / Q000188:drug therapy / Q000628:therapy*; D017147:Defibrillators, Implantable; D004992:Ethics, Medical; D006801:Humans; D016032:Randomized Controlled Trials as Topic; D012107:Research Design; D015983:Selection Bias
chemical_list: D000889:Anti-Arrhythmia Agents