Platelet apheresis for extreme thrombocytosis in an 11-year-old girl with CML.
This report describes the dramatic reduction in the platelet count and ablation of symptoms by consecutive platelet apheresis in a young girl with CML who presented with an extremely high platelet count of 10,320 x 10(9)/l. Extreme thrombocytosis, although quite rare, can be symptomatic and life-threatening in paediatric patients and should be considered an emergency. The mechanical removal of platelets by apheresis is effective therapy and should begin as soon as possible.
McCarthy
L J
LJ
Indiana University School of Medicine, Indianapolis 46202-5283, USA.
Graves
V L
VL
Eigen
H
H
McGuire
W A
WA
D002648:Child; D005260:Female; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications*; D010976:Platelet Count; D010983:Plateletpheresis; D013922:Thrombocytosis / Q000209:etiology / Q000628:therapy*