[Exercise performance and body composition in patients with chronic obstructive pulmonary disease].
Malnutritions is one cause of exercise intolerance in patients with chronic obstructive pulmonary disease. We studied the relation between exercise limitation and body composition in 20 clinically stable patients with chronic obstructive pulmonary disease. Maximal work capacity was measured during incremental exercise on a cycle ergometer, along with maximal oxygen uptake. Anaerobic threshold was determined by the V-slope method. Bone mineral content, lean mass, and fat mass were assessed by dual-energy X-ray absorptiometry. Bone mineral content and lean mass were significantly lower in moderately malnourished patients (%IBW < 80) than in well-nourished patients (%IBW > or = 90). Fat mass was significantly lower in mildly malnourished patients than in well-nourished patients. Maximal work capacity, maximal oxygen uptake, and anaerobic threshold correlated significantly with lean mass, but not with fat mass. These data suggest that lean mass is one determinant of exercise capacity in patients with chronic obstructive pulmonary disease.
Yoshikawa
M
M
Second Department of Internal Medicine, Nara Medical University, Japan.
Kobayashi
A
A
Yamamoto
C
C
Fu
A
A
Takenaka
H
H
Ikuno
M
M
Yoneda
T
T
Narita
N
N
Nezu
K
K
Kitamura
S
S
D000368:Aged; D001823:Body Composition; D017079:Exercise Tolerance / Q000502:physiology*; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000503:physiopathology*; D008297:Male