Monoamine oxidase inhibitors and cardiac anesthesia revisited.
There are well-recognized adverse interactions between the monoamine oxidase inhibitors and anesthetic drugs, particularly narcotics. Patients having cardiopulmonary bypass procedures are commonly anesthetized using high-dose narcotic techniques. We describe an uneventful perioperative course in a parkinsonian patient who required urgent coronary artery bypass graft surgery while he was taking selegiline, a selective inhibitor of monoamine oxidase type B.
Noorily
S H
SH
Department of Anesthesiology, University of Texas Health Science Center, San Antonio 78284-7838, USA.
Hantler
C B
CB
Sako
E Y
EY
D000368:Aged; D018681:Anesthetics, General / Q000009:adverse effects*; D000978:Antiparkinson Agents / Q000009:adverse effects; D001026:Coronary Artery Bypass; D004347:Drug Interactions; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008297:Male; D008996:Monoamine Oxidase Inhibitors / Q000009:adverse effects*; D009294:Narcotics / Q000009:adverse effects*; D010300:Parkinson Disease / Q000188:drug therapy; D012642:Selegiline / Q000009:adverse effects*
D018681:Anesthetics, General; D000978:Antiparkinson Agents; D008996:Monoamine Oxidase Inhibitors; D009294:Narcotics; D012642:Selegiline