title: Failure of therapeutic ultrasound in healing burn injuries.
abstract: Experimental observations suggest that therapeutic ultrasound stimulates wound healing. Despite the controversy concerning its efficiency, this procedure is commonly implemented. To study the effect of this treatment in burns, we conducted a randomized control trail in 20 Fischer rats. Two groups of 10 animals each were studied, In group 1 the experimental burn was treated with pulsed ultrasound (SATA 0.25 W/cm2), in group 2 with continuous ultrasound (0.3 W/cm2). No stimulating effect of ultrasound could be demonstrated in these two groups, monitored by histological examination and a size index. These results discourage the clinical administration of therapeutic ultrasound to enhance the healing of burns.
authors.affiliation: Department of Motor Rehabilitation and Physiotherapy, Faculty of Medicine, University Hospital, Ghent, Belgium.
authors.forename: D C
authors.initials: DC
authors.lastname: Cambier
authors.forename: G G
authors.initials: GG
authors.lastname: Vanderstraeten
mesh_terms: D000818:Animals; D002056:Burns / Q000209:etiology / Q000473:pathology / Q000628:therapy*; D004195:Disease Models, Animal; D005260:Female; D051381:Rats; D011916:Rats, Inbred F344; D012867:Skin / Q000293:injuries / Q000473:pathology; D017211:Treatment Failure; D014464:Ultrasonic Therapy; D014945:Wound Healing