Postcolumn chemiluminescence as a detection technique in the liquid chromatographic analysis of beta-lactam ring containing compounds.
A broad range of compounds containing the beta-lactam ring were screened for enhancement of luminol chemiluminescence. A selection of these compounds were found to enhance the chemiluminescence of luminol. A high-performance liquid chromatographic method for the analysis of some beta-lactams employing postcolumn chemiluminescence was developed via flow injection analysis studies.
Miyawa
J H
JH
Dept of Medicinal Chemistry, University of Florida, Gainesville 32610, USA.
Schulman
S G
SG
Perrin
J H
JH
D002138:Calibration; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D007202:Indicators and Reagents / Q000737:chemistry; D008163:Luminescent Measurements; D008165:Luminol / Q000737:chemistry; D047090:beta-Lactams / Q000032:analysis* / Q000737:chemistry
D007202:Indicators and Reagents; D047090:beta-Lactams; D008165:Luminol