Serum sialic acid and its relationship to various haematological parameters, including erythrocyte sedimentation rate.
Serum total sialic acid (TSA) has been reported to be a marker or risk factor for cardiovascular disease. The reason for this is not clear, although it has been suggested that serum TSA is a marker of the acute phase response. We measured serum TSA and various haematological parameters in 40 subjects. Significant correlations of serum TSA with erythrocyte sedimentation rate (ESR) (r = 0.65, P < 0.0001), platelet count (r = 0.65, P < 0.0001) and neutrophil count (r = 0.33, P < 0.05) were found. There was an inverse correlation with haemoglobin concentration (r = -0.62, P < 0.0001) and erythrocyte count (r = -0.42, P < 0.01).
Crook
M A
MA
Department of Chemical Pathology, Guy's Hospital, London, England, UK.
Haq
M
M
Tutt
P
P
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015415:Biomarkers / Q000097:blood; D001772:Blood Cell Count; D001799:Blood Sedimentation; D002318:Cardiovascular Diseases / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019158:N-Acetylneuraminic Acid / Q000097:blood*
D015415:Biomarkers; D019158:N-Acetylneuraminic Acid