title: Balloon aortic valvuloplasty.
abstract: Balloon aortic valvuloplasty is a percutaneous, therapeutic option for patients with severe aortic stenosis, yet the effectiveness of this procedure is dependent on the morphology of the stenotic aortic valve and the respective mechanism of dilation. In younger patients with congenital aortic stenosis, acute and intermediate-term results are good. However, in adult patients, in whom degenerative aortic stenosis is the most common cause, the acute clinical and hemodynamic benefits of balloon aortic valvuloplasty are not lasting, as restenosis occurs in most patients within 6 months. Sympatomatic relief for adults undergoing balloon aortic valvuloplasty is only apparent in patients with normal left ventricular function, who generally are also candidates for aortic valve replacement. Furthermore, the long-term survival for adults after balloon aortic valvuloplasty is similar to the natural history of untreated severe aortic stenosis. In this article, the mechanism of balloon aortic valvuloplasty, as well as its clinical and hemodynamic effects, are reviewed in the context of the different morphological types of aortic stenosis. In addition, two large registries of adult patients treated with balloon aortic valvuloplasty provide important information regarding the acute and long-term results of this procedure and are reviewed.
authors.affiliation: Division of Cardiology, Duke University Medical Center, Durham, NC 27710, USA.
authors.forename: A
authors.initials: A
authors.lastname: Wang
authors.forename: J K
authors.initials: JK
authors.lastname: Harrison
authors.forename: T M
authors.initials: TM
authors.lastname: Bashore
mesh_terms: D000328:Adult; D000368:Aged; D001024:Aortic Valve Stenosis / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D002404:Catheterization / Q000009:adverse effects / Q000379:methods / Q000401:mortality; D006350:Heart Valve Prosthesis; D006801:Humans; D008875:Middle Aged; D012449:Safety; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome