title: Protective antibody after a 'one dollar' hepatitis B vaccine.
abstract: The seropositivity rate of anti-HBs after hepatitis B vaccines, "Hepavax B", a one-dollar per dose vaccine produced by Korean Green Cross Corporation, Korea which were widely distributed and used for the first few years in the National Expanded Program on Immunization in Thailand were assessed in children who regularly came for immunization at the Well Baby Clinic at the Children's Hospital between June to December 1994. The schedule for hepatitis B immunization is at birth, 2 and 6 months of age. The seropositivity rate of anti-HBs at 6 months after the last dose were 86.3% and 87.7% at 12 months which was comparable to the seropositivity rate after other more expensive hepatitis B vaccines at 2 years (88.1%). This result should convince people that a one-dollar hepatitis B vaccine, "Hepavax" is immunogenic and expected to be as effective as other expensive hepatitis B vaccines. The marked reduce in the cost of hepatitis B vaccines will enable us to prevent and ultimately control of worldwide hepatitis B infections in the future.
authors.affiliation: Children's Hospital, Bangkok, Thailand.
authors.forename: S
authors.initials: S
authors.lastname: Kalayanarooj
authors.forename: D W
authors.initials: DW
authors.lastname: Vaughn
authors.forename: C
authors.initials: C
authors.lastname: Ariyasriwatana
authors.forename: R
authors.initials: R
authors.lastname: Snitbhan
mesh_terms: D003365:Costs and Cost Analysis; D006509:Hepatitis B / Q000276:immunology / Q000517:prevention & control; D006510:Hepatitis B Antibodies / Q000276:immunology*; D017325:Hepatitis B Vaccines / Q000191:economics / Q000276:immunology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D013785:Thailand
chemical_list: D006510:Hepatitis B Antibodies; D017325:Hepatitis B Vaccines