title: Bovine rotavirus 993/83 shows a third subtype of avian VP7 protein.
abstract: VP7 genes of rotavirus (RV) 993/83 isolated from a German calf with diarrhea and of RV PO-13 isolated from a Japanese pigeon were sequenced. Alignment of the deduced VP7 amino acid sequence showed 98.8% sequence identity, while only 70% and 84% identity was seen with VP7 from chicken RV Ch-2 and turkey RV Ty-1, respectively. Over the antigenic regions A, B, and C mammalian RV 993/83 showed more aa identity with mammalian G3 RVs than with chicken RV Ch-2, which could explain the strong one-way cross-neutralization observed between RV 993/83 and G3 RVs. Despite marked VP7 sequence diversity avian RVs could not be differentiated into distinct G types.
authors.affiliation: Department of Medical Microbiology and Virology, Ruhr-University Bochum, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Rohwedder
authors.forename: H
authors.initials: H
authors.lastname: Hotop
authors.forename: N
authors.initials: N
authors.lastname: Minamoto
authors.forename: H
authors.initials: H
authors.lastname: Ito
authors.forename: O
authors.initials: O
authors.lastname: Nakagomi
authors.forename: H
authors.initials: H
authors.lastname: Brüssow
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000956:Antigens, Viral / Q000235:genetics; D002213:Capsid / Q000145:classification* / Q000235:genetics* / Q000276:immunology; D036022:Capsid Proteins; D002417:Cattle; D002645:Chickens; D010856:Columbidae; D006801:Humans; D008322:Mammals; D008969:Molecular Sequence Data; D010802:Phylogeny; D012401:Rotavirus / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification; D017386:Sequence Homology, Amino Acid; D012703:Serotyping; D013045:Species Specificity; D014422:Turkeys
chemical_list: D000956:Antigens, Viral; D036022:Capsid Proteins; C050779:VP7 protein, Rotavirus