Odontogenic myxoma in an adolescent with tuberous sclerosis.
Tuberous sclerosis is a hamartoneoplastic syndrome characterised by early onset of convulsive seizures with mental retardation. Oral abnormalities, including enamel hypoplasia and mucosal fibromas, have been previously reported. We report here a 17-year-old girl with this disorder who had received repeated dental trauma. She presented with a swelling associated with a traumatised maxillary central incisor that suggested a diagnosis other than the odontogenic myxoma found at operation. Odontogenic myxoma has not previously been reported in this condition; it may represent an unusual phenotypic expression of the genetic defect understood to determine tuberous sclerosis, or it may be an unrelated coincidental finding.
Harrison
M G
MG
Guy's Dental Hospital, London, UK.
O'Neill
I D
ID
Chadwick
B L
BL
D000293:Adolescent; D005260:Female; D006801:Humans; D008441:Maxillary Neoplasms / Q000150:complications / Q000175:diagnosis*; D009232:Myxoma / Q000150:complications / Q000175:diagnosis*; D009808:Odontogenic Tumors / Q000150:complications / Q000175:diagnosis*; D014402:Tuberous Sclerosis / Q000150:complications* / Q000175:diagnosis