Growth control: action mouse.
A recently described knockout mouse has abnormally large muscles. The phenotype suggests that the ablated product, growth differentiation factor 8 or 'myostatin', may be one of the long sought inhibitors that control the growth of individual tissues and organs.
Slack
J M
JM
Department of Biology and Biochemistry, University of Bath, UK.
D000818:Animals; D005246:Feedback; D051379:Mice; D018345:Mice, Knockout; D008954:Models, Biological; D024510:Muscle Development; D055435:Myostatin; D009928:Organ Specificity; D010641:Phenotype; D016212:Transforming Growth Factor beta / Q000235:genetics* / Q000502:physiology*
C525912:Mstn protein, mouse; D055435:Myostatin; D016212:Transforming Growth Factor beta