Identification of a new strain of fastidious enterovirus 70 as the causative agent of an outbreak of hemorrhagic conjunctivitis.
A 1994 outbreak of acute hemorrhagic conjunctivitis in Israel was caused by an enterovirus 70 strain that was distinct from previously reported strains. Characterization was by electron microscopy (eye washes), reverse transcription-PCR (RT-PCR; eyewash, specimens, eye swabs, and tears), and sequence analysis of RT-PCR-amplified fragments from the 5' noncoding region and VP1.
Shulman
L M
LM
Central Virology Laboratory, Sheba Medical Center, Tel Hashomer, Israel. cvlsheba@netvision.net.il
Manor
Y
Y
Azar
R
R
Handsher
R
R
Vonsover
A
A
Mendelson
E
E
Rothman
S
S
Hassin
D
D
Halmut
T
T
Abramovitz
B
B
Varsano
N
N
D000595:Amino Acid Sequence; D001483:Base Sequence; D003232:Conjunctivitis, Acute Hemorrhagic / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis*; D004268:DNA-Binding Proteins / Q000235:genetics*; D004770:Enterovirus / Q000235:genetics* / Q000302:isolation & purification; D004769:Enterovirus Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000821:virology*; D006801:Humans; D007557:Israel / Q000453:epidemiology; D008969:Molecular Sequence Data; D010802:Phylogeny; D010940:Plant Proteins; D016133:Polymerase Chain Reaction; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid; D015534:Trans-Activators; D014157:Transcription Factors / Q000235:genetics*
D004279:DNA, Viral; D004268:DNA-Binding Proteins; D010940:Plant Proteins; D015534:Trans-Activators; D014157:Transcription Factors