title: Platelet apheresis for extreme thrombocytosis in an 11-year-old girl with CML.
abstract: This report describes the dramatic reduction in the platelet count and ablation of symptoms by consecutive platelet apheresis in a young girl with CML who presented with an extremely high platelet count of 10,320 x 10(9)/l. Extreme thrombocytosis, although quite rare, can be symptomatic and life-threatening in paediatric patients and should be considered an emergency. The mechanical removal of platelets by apheresis is effective therapy and should begin as soon as possible.
authors.affiliation: Indiana University School of Medicine, Indianapolis 46202-5283, USA.
authors.forename: L J
authors.initials: LJ
authors.lastname: McCarthy
authors.forename: V L
authors.initials: VL
authors.lastname: Graves
authors.forename: H
authors.initials: H
authors.lastname: Eigen
authors.forename: W A
authors.initials: WA
authors.lastname: McGuire
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications*; D010976:Platelet Count; D010983:Plateletpheresis; D013922:Thrombocytosis / Q000209:etiology / Q000628:therapy*