title: [The pathomorphology and pathogenesis of glanders in laboratory animals].
abstract: The pathomorphology and cell-mediated response of the body to Burkholderia mallei in laboratory animals, highly sensitive and resistant to these bacteria. In the comparative study of the pathomorphology and pathogenesis of glanders in golden hamsters and white rats quantitative and qualitative differences in the histogenesis of response reaction and the morphology of immunocompetent organs were established. Cell-mediated reactions play a greater role in the limitation of the early spread of B. mallei in the host body than antigen-mediated mechanisms.
authors.forename: N R
authors.initials: NR
authors.lastname: Diadishchev
authors.forename: A A
authors.initials: AA
authors.lastname: Vorob'ev
authors.forename: S B
authors.initials: SB
authors.lastname: Zakharov
mesh_terms: D000818:Animals; D019117:Burkholderia / Q000302:isolation & purification / Q000472:pathogenicity; D006224:Cricetinae; D005260:Female; D005896:Glanders / Q000209:etiology* / Q000276:immunology / Q000382:microbiology / Q000473:pathology*; D007113:Immunity, Innate; D007740:L Forms / Q000302:isolation & purification / Q000472:pathogenicity; D008297:Male; D008647:Mesocricetus; D051381:Rats; D013997:Time Factors; D014774:Virulence
vernacular_title: Patomorfologiia i patogenez sapa u laboratornykh zhivotnykh.