title: Scintigraphic assessment of distal extremity perfusion in 17 patients.
abstract: To assess the role of scintigraphic evaluation of distal limb perfusion, the medical records and scintigraphic perfusion images of 17 animals (8 dogs, 2 cats, 2 calves, 4 birds and 1 ferret) with clinical signs of distal limb ischemia were examined retrospectively. Images were obtained at 5 and 10 minutes following injection of 99mTc-MDP, or 99mTc-DTPA. The initial scintigraphic diagnoses of 17 animals included complete ischemia (8/17), partially reduced perfusion (5/17), and normal to increased perfusion (4/17). In 4 of the animals with partially reduced perfusion, follow-up scans indicated progression to complete ischemia (1/4) or normal to increased perfusion (3/4). Nine of 17 animals had a final scintigraphic diagnosis of complete distal limb ischemia, and these animals were either euthanized (5/9) or had limb amputation (4/9). A final diagnosis of complete ischemia was supported with either repeat scanning (3/10), continued clinical observation (6/10) and/or pathological examination (10/10). Clinical signs of ischemia resolved in all (7/17) animals with increased or normal perfusion on their final scan. Scintigraphy provided a safe and noninvasive assessment of distal limb perfusion, which corresponded with clinical outcome.
authors.affiliation: Department of Clinical Sciences, Kansas State University, College of Veterinary Medicine, Manhattan 66506-5606, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Goggin
authors.forename: J J
authors.initials: JJ
authors.lastname: Hoskinson
authors.forename: J W
authors.initials: JW
authors.lastname: Carpenter
authors.forename: J K
authors.initials: JK
authors.lastname: Roush
authors.forename: R M
authors.initials: RM
authors.lastname: McLaughlin
authors.forename: D E
authors.initials: DE
authors.lastname: Anderson
mesh_terms: D000671:Amputation, Surgical / Q000662:veterinary; D000820:Animal Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D000818:Animals; D001715:Bird Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D001717:Birds; D002371:Cat Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D002415:Cats; D002417:Cattle; D002418:Cattle Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D018450:Disease Progression; D004283:Dog Diseases / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D004285:Dogs; D005065:Euthanasia / Q000662:veterinary; D005289:Ferrets; D005500:Follow-Up Studies; D006614:Hindlimb / Q000098:blood supply* / Q000601:surgery; D006940:Hyperemia / Q000503:physiopathology / Q000662:veterinary; D007511:Ischemia / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery / Q000662:veterinary*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D012039:Regional Blood Flow; D012189:Retrospective Studies; D013669:Technetium Tc 99m Medronate; D016284:Technetium Tc 99m Pentetate; D016896:Treatment Outcome
chemical_list: D019275:Radiopharmaceuticals; D016284:Technetium Tc 99m Pentetate; D013669:Technetium Tc 99m Medronate