title: [Brain functional MRI using 3D-SPGR pulse sequence].
abstract: We reported the effects of motor cortex stimulation of normal volunteers using conventional MR imaging techniques on standard 1.5 T clinical scanner. The imaging technique was an optimized conventional 2D and 3D spoiled GRASS. In the 3D-SPGR measurement, a slab of 96 mm with 32 partition was evaluated in sagital direction. The motor cortex stimulation was achieved by touching each finger to thumb in a sequential, self-paced, and repetitive manner. During stimulation, areas of increased signal intensity were identified in the sensorimotor cortex with both 2D and 3D SPGR method. The 3D-SPGR method in sagital direction is rather insensitive to inflow effects, thus signal increases with 3D-SPGR method is mainly due to the blood oxygenation level dependent effects.
authors.affiliation: Department of Radiology, National Toneyama Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
authors.forename: T
authors.initials: T
authors.lastname: Nishimura
mesh_terms: D001921:Brain / Q000033:anatomy & histology* / Q000502:physiology; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009044:Motor Cortex / Q000033:anatomy & histology / Q000502:physiology; D010108:Oxyhemoglobins / Q000378:metabolism; D010812:Physical Stimulation
chemical_list: D010108:Oxyhemoglobins