title: Prenatal diagnosis of an extensive fetal lymphangioma using ultrasonography, magnetic resonance imaging and cytology.
abstract: An unusual case of fetal lymphangioma diagnosed before delivery is reported in a second trimester pregnant woman. The lymphangioma was suspected at 28 weeks on the basis of the ultrasound appearances and progression of the lesions with advancing gestation. MRI was used to evaluate the extent and the tissue characteristics of the lesions. Cytology of the fluid aspirated from the cystic lesions showed abundant lymphocytes and macrophages, confirming the diagnosis of a lymphangioma. The parents opted for a pregnancy termination because of the rapid growth of the lesions and the poor prognosis. It is suggested that the combination of these tests could enable the early diagnosis of these tumours at a stage when the lesion is relatively limited and accessible to therapy in utero.
authors.affiliation: Fetal Medicine Unit, St James's University Hospital, Leeds, UK.
authors.forename: P
authors.initials: P
authors.lastname: Kaminopetros
authors.forename: E
authors.initials: E
authors.lastname: Jauniaux
authors.forename: P
authors.initials: P
authors.lastname: Kane
authors.forename: M
authors.initials: M
authors.lastname: Weston
authors.forename: K H
authors.initials: KH
authors.lastname: Nicolaides
authors.forename: D J
authors.initials: DJ
authors.lastname: Campbell
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008202:Lymphangioma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*; D012186:Retroperitoneal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D016216:Ultrasonography, Prenatal