title: [Urolithiasis in children in West Algeria].
abstract: We analyzed a series of 61 stones from children aged 3 to 14 years old using Fourier transform infrared spectroscopy. The calculi were collected from urology departments of the University Hospitals of Oran, Sidi-Bel-Abbès and Mostaganem in West Algeria. This series is the first investigation concerning the composition of stones in children based on infrared analysis. Calculi were more frequent in males (75.4%) and mainly localized in the bladder (55.8%). Upper urinary tract calculi were more frequent in children over the age of 10 years, and the sex ratio was about 1. Calcium oxalate monohydrate was present in 70.5% of stones and was the main component in 50.8% of cases both in whole stones and nuclei. In contrast, calcium oxalate dihydrate was the main component in only 9.8% of calculi although it was present in 75.4% of stones. Ammonium urate was detected in 29.5% of stones and was always the main component of nuclei. Uric acid, observed in 31.1% of calculi, was the major constituent in 14.7% of stones and 19.7% of nuclei. Magnesium ammonium phosphate was observed in 24.6% of stones as a consequence of urinary tract infection by urea-splitting bacteria. Our observations emphasized that the anatomical location of stone and their composition were in accordance with those previously reported in other countries.
authors.affiliation: Département de Chimie, Université de Sidi-Bel-Abbes, Algérie.
authors.forename: D
authors.initials: D
authors.lastname: Harrache
authors.forename: A
authors.initials: A
authors.lastname: Mesri
authors.forename: A
authors.initials: A
authors.lastname: Addou
authors.forename: A
authors.initials: A
authors.lastname: Semmoud
authors.forename: B
authors.initials: B
authors.lastname: Lacour
authors.forename: M
authors.initials: M
authors.lastname: Daudon
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000462:Algeria / Q000453:epidemiology; D002129:Calcium Oxalate / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000453:epidemiology; D017616:Magnesium Compounds / Q000032:analysis; D008297:Male; D010710:Phosphates / Q000032:analysis; D012737:Sex Factors; D013057:Spectrum Analysis; D000069877:Struvite; D014514:Ureteral Calculi / Q000453:epidemiology; D014527:Uric Acid / Q000032:analysis; D001744:Urinary Bladder Calculi / Q000453:epidemiology; D014545:Urinary Calculi / Q000737:chemistry / Q000453:epidemiology*
chemical_list: D017616:Magnesium Compounds; D010710:Phosphates; D002129:Calcium Oxalate; D014527:Uric Acid; D000069877:Struvite
vernacular_title: La lithiase urinaire chez l'enfant dans l'Ouest-Algérien.