Rifampicin and isoniazid in the treatment of leprous nerve abscesses.
Thirty nine cases of borderline tuberculoid leprosy having nerve abscesses (15 with sinuses) were treated with daily dose of rifampicin and isoniazid for six months along with standard multidrug therapy. The patients were followed up for three to five years. No recurrence of abscess or sinus was observed. Observations indicate that medical approach is required at times to supplement surgical intervention for management of these cases.
Husain
S
S
Central Jalma Institute for Leprosy, Tajganj, Agra, India.
Mishra
B
B
Malaviya
G N
GN
D000038:Abscess / Q000188:drug therapy* / Q000382:microbiology; D000328:Adult; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007538:Isoniazid / Q000627:therapeutic use*; D007917:Leprostatic Agents / Q000627:therapeutic use*; D015439:Leprosy, Borderline / Q000150:complications*; D015441:Leprosy, Tuberculoid / Q000150:complications*; D008297:Male; D009422:Nervous System Diseases / Q000188:drug therapy* / Q000382:microbiology; D012293:Rifampin / Q000627:therapeutic use*; D016896:Treatment Outcome
D007917:Leprostatic Agents; D007538:Isoniazid; D012293:Rifampin