title: Incidence of bloodborne virus infection and risk behaviours in a cohort of injecting drug users in Victoria, 1990-1995.
abstract: OBJECTIVE
  To assess changes in risk behaviours for transmission of bloodborne viruses and incidences and prevalences of these viruses in a field-recruited cohort of injecting drug users.
  
  
  METHODS
  Prospective longitudinal cohort study.
  
  
  METHODS
  Metropolitan and rural Victoria, June 1990 to December 1995.
  
  
  METHODS
  626 current injecting drug users (i.e., who had injected drugs within the previous 12 months).
  
  
  METHODS
  Seroconversion to HIV and hepatitis B and C viruses (HBV and HCV), risk behaviours for infection.
  
  
  RESULTS
  HIV incidence was very low (0.2 per 100 person-years). HCV incidence was high (10.7 per 100 person-years), but fell throughout the study, although the downward trend did not reach statistical significance. HBV incidence was moderate (1.8 per 100 person-years) and did not fall. Prevalence of risk behaviours, notably sharing needles and syringes, decreased significantly.
  
  
  CONCLUSIONS
  Significant change has occurred in the risk behaviours of the cohort, confirming results of cross-sectional studies of injecting drug use. This change may be responsible for the apparent decline in HIV and HCV incidence. Further studies are needed to monitor the incidence of bloodborne viruses in injecting drug users. Efforts to decrease risk of transmission should continue.
authors.affiliation: Epidemiology and Social Research Unit, Macfarlane Burnet Centre for Medical Research, Melbourne, VIC. crofts@mbcmr.unimelb.edu.au
authors.forename: N
authors.initials: N
authors.lastname: Crofts
authors.forename: C K
authors.initials: CK
authors.lastname: Aitken
mesh_terms: D000293:Adolescent; D000328:Adult; D017848:Blood-Borne Pathogens; D005260:Female; D015658:HIV Infections / Q000453:epidemiology*; D006509:Hepatitis B / Q000453:epidemiology*; D006526:Hepatitis C / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D016485:Needle Sharing / Q000009:adverse effects; D015995:Prevalence; D011446:Prospective Studies; D012307:Risk Factors; D012309:Risk-Taking; D015819:Substance Abuse, Intravenous / Q000150:complications* / Q000523:psychology; D014739:Victoria / Q000453:epidemiology