[Selection of mice for brain weight].
The results of two experiments on selection of laboratory mice for large and small brain weight are presented. Selection was based on the regression relationship between body and brain weight. This allowed considerable differences in brain weight to be obtained accompanied by insignificant interlinear differences in body weight compared to the range of intralinear variation. The two lines of mice with a large and small brain weight (F9-F10) differed significantly in brain weight. The absolute difference was 60-70 mg, i.e., approximately 13% of the brain weight in the original heterogeneous population.
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D000818:Animals; D001835:Body Weight / Q000235:genetics; D001921:Brain / Q000033:anatomy & histology*; D051379:Mice; D008815:Mice, Inbred Strains; D009929:Organ Size / Q000235:genetics; D012044:Regression Analysis; D012641:Selection, Genetic; D013045:Species Specificity
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