title: Nontuberculous mycobacterial cervical adenitis.
abstract: Granulomatous inflammation is a common finding in pathologic evaluation of surgically excised chronic lymphadenopathy in children. Confusion exists regarding diagnosis and management of these lesions. Over a 10-year period at The Children's Hospital of Philadelphia, a total of 81 children were identified with biopsy-confirmed granulomatous lesions of the head and neck, with nontuberculous mycobacteria (NTM) accounting for 67 of the cases. The typical presentation was that of a nontender mass in the cervicofacial area present for weeks to months, unresponsive to antimicrobials. All underwent surgical excision, which was curative in 54 patients; 13 children required additional procedures. This paper reviews NTM, its typical clinical presentation, difficulty in diagnosis, and the methods of treatment.
authors.affiliation: Division of Otolaryngology, Children's Hospital of Philadelphia, PA 19104, USA.
authors.forename: D L
authors.initials: DL
authors.lastname: Suskind
authors.forename: S D
authors.initials: SD
authors.lastname: Handler
authors.forename: L W
authors.initials: LW
authors.lastname: Tom
authors.forename: W P
authors.initials: WP
authors.lastname: Potsic
authors.forename: R F
authors.initials: RF
authors.lastname: Wetmore
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006099:Granuloma / Q000382:microbiology; D006801:Humans; D007223:Infant; D008198:Lymph Nodes / Q000382:microbiology*; D008199:Lymphadenitis / Q000382:microbiology*; D008297:Male; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D009333:Neck; D014376:Tuberculosis / Q000175:diagnosis