title: [Prognostic factors of renal adenocarcinoma: study of a series of 233 patients].
abstract: OBJECTIVE
  To identify certain prognostic factors of renal cell carcinoma in a retrospective series of 233 patients.
  
  
  METHODS
  233 patients (162 males and 71 females with a mean age of 60 years) were operated for renal cell carcinoma between January 1980 and December 1991. sith a mean follow-up of 41.7 months. Statistical analysis was performed according to the Kaplan-Meier method for survival curves, according to the Mantel-Cox model for univariate or multivariate analysis and according to Student's t test and Chi-square test for comparison of quantitative and qualitative variables.
  
  
  RESULTS
  The operative and global mortality was 2.2% and 28%, respectively. The following prognostic factors were identified: visceral metastases (p = 0.0001), lymph node invasion (p = 0.001), symptomatic nature of the tumour (p = 0.0004), local pathological stage (p = 0.0001) and nuclear grade (p = 0.0001). Multivariate analysis showed that the first 3 factors were the most pejorative (relative risk (RR) = 6.7, 4.6, and 1.7, respectively). Venous invation, multifocal tumours, and cell type were not studied in our series.
  
  
  CONCLUSIONS
  This study confirmed that metastases, lymph node invasion and symptomatic tumours were the most pejorative prognostic factors.
authors.affiliation: Service d'Urologie, Hôpital Salvator, Marseille, France.
authors.forename: A
authors.initials: A
authors.lastname: Koutani
authors.forename: D
authors.initials: D
authors.lastname: Bretheau
authors.forename: E
authors.initials: E
authors.lastname: Lechevallier
authors.forename: M
authors.initials: M
authors.lastname: de Fromont
authors.forename: M
authors.initials: M
authors.lastname: Rampal
authors.forename: C
authors.initials: C
authors.lastname: Coulange
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000473:pathology / Q000556:secondary / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate
vernacular_title: Les facteurs pronostiques de l'adénocarcinome rénal: Etude d'une série de 233 patients.