Analysis of skeletal and cardiac muscle from desmin knock-out and normal mice by high resolution separation of myosin heavy-chain isoforms.
In this study, using a modified electrophoretic technique, we have defined in the mouse the myosin heavy-chain composition of both newborn and adult skeletal and cardiac muscles. Using this high resolution technique it was possible to detect modifications in the myosin heavy-chain expression in both cardiac and skeletal muscles of desmin knock-out mice.
Agbulut
O
O
CNRS-URA 1448, UFR Biomedical de St-Pères, Paris, France.
Li
Z
Z
Mouly
V
V
Butler-Browne
G S
GS
D000818:Animals; D003893:Desmin / Q000235:genetics / Q000378:metabolism*; D004586:Electrophoresis; D051379:Mice; D018345:Mice, Knockout; D018482:Muscle, Skeletal / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D018995:Myosin Heavy Chains / Q000032:analysis*
D003893:Desmin; D018995:Myosin Heavy Chains