[Results of direct revascularization of choroid: an experimental study].
The morphology of histological slices of tissue at the site of direct revascularization of the choroid was assessed in various periods (15 days, 1, 3, and 6 months) after surgery. The surgical method was as follows: a collagen hemostatic sponge, a strip of subconjunctival tissue, and tissue of the external rectal muscle were put onto an exposed 4 x 4 mm site of the choroid and closed with an episcleral flap fixed with nodular sutures without pulling. Experiments were carried out on 13 rabbits (26 eyes). Direct revascularization of the choroid was performed in all animals. The animals were sacrificed by air embolism 15 days, 1, 3, and 6 months after surgery. Vascular filling was carried out. The eyes were enucleated, paraffin slices were prepared from tissues at the site of operation, and the slices were stained with hematoxylin-eosin, tholuidine blue, and after Van Gieson. After direct revascularization of the choroid with episcleral, muscular, and subconjunctival tissue and collagen sponge numerous full-value vascular formations are seen at the site of the intervention as early as 3 months after surgery; these vascular formations connect the extraorbital tissues rich in vessels with the vascular coating; the number of newly formed vessels increases by 6 months postoperation. The results of experiments give good grounds for clinical use of the method.
Basinskiĭ
S N
SN
Department of Eye Diseases of Amur State Medical Academy, Blagoveshchensk.
Grigorenko
A A
AA
Krasnogorskaia
V N
VN
Solomina
E V
EV
D000818:Animals; D002829:Choroid / Q000098:blood supply* / Q000473:pathology / Q000601:surgery; D004195:Disease Models, Animal; D005260:Female; D005500:Follow-Up Studies; D008297:Male; D008833:Microcirculation; D008866:Microsurgery / Q000379:methods; D018919:Neovascularization, Physiologic; D011817:Rabbits; D016896:Treatment Outcome
Rezultaty operatsii priamoĭ revaskuliarizatsii khoroidei v éksperimene.