Chemical and pharmacological studies on fixed oil of Ocimum sanctum.
Gas liquid chromatographic analysis of fixed oil of O. sanctum revealed the presence of five fatty acids (stearic, palmitic, oleic, linoleic and linolenic acids). The triglyceride fraction of the oil showed higher protection compared to fixed oil against carrageenam-induced paw edema and acetic acid-induced writhings in rats and mice, respectively. The pharmacological activity of the fixed oil could be attributed to its triglyceride fraction or the fatty acids.
Singh
S
S
College of Pharmacy (University of Delhi) Pushp Vihar, India.
Majumdar
D K
DK
Yadav
M R
MR
D000700:Analgesics / Q000737:chemistry* / Q000494:pharmacology; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000737:chemistry* / Q000494:pharmacology; D005227:Fatty Acids / Q000032:analysis; D005260:Female; D008297:Male; D051379:Mice; D018649:Ocimum basilicum / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D010938:Plant Oils / Q000737:chemistry* / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D014280:Triglycerides
D000700:Analgesics; D000893:Anti-Inflammatory Agents; D005227:Fatty Acids; D010936:Plant Extracts; D010938:Plant Oils; D014280:Triglycerides