Chronic intestinal infection due to subgenus F type 40 adenovirus in a patient with AIDS.
A case of chronic intestinal infection due to adenovirus type 40 lasting for 13 months in a patient with AIDS is described. Adenovirus particles were detected by electron microscopy in biopsy samples taken from the duodenum 3 months after the onset of diarrhoea. The virus was identified as adenovirus type 40 in stool samples by ELISA monoclonal antibodies to adenovirus group antigen (MAd-g2) and types 40 and 41 (MA 40-1 and MA 41-1). No other enteropathogens were found. These data support a causal relationship between adenovirus 40 and the gastrointestinal symptoms of the patient. This is the first reported case of intestinal infection caused by adenovirus type 40 in a patient with AIDS.
Dionisio
D
D
Infectious Diseases Unit, Careggi Hospital, Florence, Italy.
Arista
S
S
Vizzi
E
E
Manneschi
L I
LI
Di Lollo
S
S
Trotta
M
M
Sterrantino
G
G
Mininni
S
S
Leoncini
F
F
D017088:AIDS-Related Opportunistic Infections / Q000473:pathology / Q000821:virology*; D000258:Adenovirus Infections, Human / Q000473:pathology / Q000821:virology*; D000260:Adenoviruses, Human / Q000302:isolation & purification*; D000328:Adult; D002908:Chronic Disease; D003967:Diarrhea / Q000821:virology; D004378:Duodenal Diseases / Q000473:pathology / Q000821:virology; D004386:Duodenum / Q000648:ultrastructure / Q000821:virology; D005243:Feces / Q000821:virology; D006801:Humans; D007410:Intestinal Diseases / Q000473:pathology / Q000821:virology*; D007413:Intestinal Mucosa / Q000648:ultrastructure / Q000821:virology; D008297:Male; D008854:Microscopy, Electron