title: Premedication with controlled release diclofenac sodium reduces post-operative pain after minor gynaecological surgery.
abstract: The effect of a single pre-operative oral dose of controlled release diclofenac sodium on post-operative pain after minor gynaecological surgery was investigated. Fifty-two women took part in a double-blind controlled study. Pain was assessed by visual analogue scale (VAS), a four-point verbal rating score, and the requirement for post-operative analgesia. Those patients who received diclofenac had significantly less post-operative pain than the placebo group up to 2 h after surgery.
authors.affiliation: Department of Anaesthesia, Whiston Hospital, Merseyside, UK.
authors.forename: M J
authors.initials: MJ
authors.lastname: Bamber
authors.forename: I E
authors.initials: IE
authors.lastname: Tweedie
authors.forename: C
authors.initials: C
authors.lastname: Breeze
authors.forename: N E
authors.initials: NE
authors.lastname: Williams
mesh_terms: D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000627:therapeutic use*; D000758:Anesthesia; D003692:Delayed-Action Preparations; D004008:Diclofenac / Q000008:administration & dosage / Q000627:therapeutic use*; D004311:Double-Blind Method; D005260:Female; D005831:Genital Diseases, Female / Q000601:surgery*; D006801:Humans; D008297:Male; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D011292:Premedication
chemical_list: D018712:Analgesics, Non-Narcotic; D003692:Delayed-Action Preparations; D004008:Diclofenac