title: Synthesis of new 2-arylidene-2H-1,4-benzoxazin-3(4H)-ones.
abstract: A number of 2-arylidene-2H-1,4-benzoxazin-3(4H)-ones were synthesized and evaluated for CNS activity. Some of the tested compounds exhibited marked CNS depressant activity in mice.
authors.affiliation: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Istanbul, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Gezginci
authors.forename: S
authors.initials: S
authors.lastname: Salman
authors.forename: A
authors.initials: A
authors.lastname: Okyar
authors.forename: G
authors.initials: G
authors.lastname: Baktir
mesh_terms: D000818:Animals; D002492:Central Nervous System Depressants / Q000138:chemical synthesis / Q000494:pharmacology; D051379:Mice; D015394:Molecular Structure; D009043:Motor Activity / Q000187:drug effects; D010078:Oxazines / Q000138:chemical synthesis / Q000494:pharmacology*
chemical_list: D002492:Central Nervous System Depressants; D010078:Oxazines