title: [Effect of patients' gender on the course of chronic myeloid leukemia].
abstract: Chronic myeloid leukemia course was evaluated versus sex in 271 patients. Chronic stage involved more pronounced leukocytosis, thrombocytosis and splenomegaly in females, the latter showing higher susceptibility to anemia. As a result, treatment has to deal with a greater mass of tumor. A relatively longer survival time in males (44 and 42 months, respectively) suggest a higher effectiveness of therapy in such patients. When diagnosed, leukocytosis, thrombocytosis, enhanced splenomegaly and anemia should be regarded as factors of unfavorable prognosis.
authors.forename: K M
authors.initials: KM
authors.lastname: Abdulkadyrov
authors.forename: O A
authors.initials: OA
authors.lastname: Rukavitzyn
authors.forename: S S
authors.initials: SS
authors.lastname: Bessmel'tsev
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Lomtev
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000740:Anemia / Q000209:etiology; D005260:Female; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000097:blood / Q000150:complications / Q000503:physiopathology*; D007964:Leukocytosis / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D012737:Sex Factors; D013163:Splenomegaly / Q000209:etiology; D016019:Survival Analysis; D013922:Thrombocytosis / Q000209:etiology
vernacular_title: Vliianie pola bol'nykh na techenie khronicheskogo mieloleĭkoza.