title: Foveal cone spacing and cone photopigment density difference: objective measurements in the same subjects.
abstract: Foveal cone spacing was measured in vivo using an objective technique: ocular speckle interferometry. Cone packing density was computed from cone spacing data. Foveal cone photopigment density difference was measured in the same subjects using retinal densitometry with a scanning laser ophthalmoscope. Both the cone packing density and cone photopigment density difference decreased sharply with increasing retinal eccentricity. From the comparison of both sets of measurements, the computed amounts of photopigment per cone increased slightly with increasing retinal eccentricity. Consistent with previous results, decreases in cone outer segment length are over-compensated by an increase in the outer segment area, at least in retinal eccentricities up to 1 deg.
authors.affiliation: Instituto de Optica, Consejo Superior de Investigaciones Cientificas, Madrid, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Marcos
authors.forename: R P
authors.initials: RP
authors.lastname: Tornow
authors.forename: A E
authors.initials: AE
authors.lastname: Elsner
authors.forename: R
authors.initials: R
authors.lastname: Navarro
mesh_terms: D000328:Adult; D000886:Anthropometry; D003720:Densitometry; D005260:Female; D005584:Fovea Centralis / Q000166:cytology*; D005654:Fundus Oculi; D006801:Humans; D007368:Interferometry / Q000379:methods; D008027:Light; D008297:Male; D009887:Ophthalmoscopy; D017949:Retinal Cone Photoreceptor Cells / Q000737:chemistry / Q000166:cytology*; D012168:Retinal Pigments / Q000032:analysis*
chemical_list: D012168:Retinal Pigments