Inhibition of the inositol triphosphate receptor increases endotoxin-mediated nitric oxide synthesis in macrophages.
Schroeder
R A
RA
Department of Surgery, University of Maryland Medical System, Baltimore, USA.
Gu
J
J
Kuo
P C
PC
D000818:Animals; D015220:Calcium Channels; D002478:Cells, Cultured; D004731:Endotoxins / Q000494:pharmacology*; D053496:Inositol 1,4,5-Trisphosphate Receptors; D008264:Macrophages / Q000378:metabolism*; D051379:Mice; D009569:Nitric Oxide / Q000096:biosynthesis*; D010716:Phosphatidylinositols / Q000737:chemistry*; D018160:Receptors, Cytoplasmic and Nuclear / Q000037:antagonists & inhibitors*; D015398:Signal Transduction / Q000187:drug effects
D015220:Calcium Channels; D004731:Endotoxins; D053496:Inositol 1,4,5-Trisphosphate Receptors; D010716:Phosphatidylinositols; D018160:Receptors, Cytoplasmic and Nuclear; D009569:Nitric Oxide