title: Rationale for the introduction of long chain polyunsaturated fatty acids and for concomitant increase in the level of vitamin E in infant formulas.
abstract: There is significant scientific agreement that human milk is the best source of nutrients for the human infant. In addition it is also agreed that the constituents of human milk and their concentrations should form the basis of infant formula compositions. The objectives of this review are two fold: to examine the data on the long chain polyunsaturated fatty acid levels (LC-PUFA) in human milk and the rationale for inclusion of these lipids in infant formulas; secondly, as a consequence of addition of highly unsaturated lipids to infant formulas, the antioxidant requirements are increased. Therefore the effect of the addition of LC-PUFA on infant vitamin E status is also examined.
authors.affiliation: Roche Vitamins Inc., Paramus, NJ 07652, USA.
authors.forename: A
authors.initials: A
authors.lastname: Bendich
authors.forename: P E
authors.initials: PE
authors.lastname: Brock
mesh_terms: D000975:Antioxidants / Q000008:administration & dosage; D005231:Fatty Acids, Unsaturated / Q000008:administration & dosage* / Q000032:analysis; D006801:Humans; D007223:Infant; D007225:Infant Food; D008895:Milk, Human / Q000737:chemistry*; D014810:Vitamin E / Q000008:administration & dosage*
chemical_list: D000975:Antioxidants; D005231:Fatty Acids, Unsaturated; D014810:Vitamin E