title: Comparison of exercise stress testing with dobutamine stress echocardiography and exercise technetium-99m isonitrile single photon emission computerized tomography for diagnosis of coronary artery disease.
abstract: To compare the value of exercise electrocardiography with dobutamine stress echocardiography and exercise technetium-99m isonitrile single-photon emission computed tomography for coronary artery disease, 70 patients with either suspected or proven coronary artery disease underwent dobutamine stress echocardiography, exercise technetium-99m isonitrile single-photon emission computed tomography (mibi-SPECT) and treadmill exercise electrocardiography (ECG). Dobutamine echocardiography and exercise mibi-SPECT revealed a higher overall sensitivity than exercise testing (90 vs 57%, p < 0.001; 96 vs 57%, p < 0.001, respectively). Dobutamine stress echocardiography showed a higher specificity than both exercise mibi-SPECT and treadmill exercise electrocardiography (90 vs 71%, p > 0.05; 90 and 62% p < 0.05, respectively) but the difference between dobutamine stress echocardiography and exercise mibi-SPECT was not statistically significant. Diagnostic accuracy of dobutamine stress echocardiography and exercise mibi-SPECT was higher than that of exercise testing (90 vs 59%, p < 0.001; 89 vs 59%, p < 0.001, respectively). Dobutamine stress echocardiography and exercise mibi-SPECT have superiority over exercise testing in the diagnosis of coronary artery disease and dobutamine stress echocardiography is an alternative for exercise mibi-SPECT.
authors.affiliation: Department of Cardiology, Ankara Yüksek Ihtisas Hospital, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Oğuzhan
authors.forename: H L
authors.initials: HL
authors.lastname: Kisacik
authors.forename: K
authors.initials: K
authors.lastname: Ozdemir
authors.forename: B B
authors.initials: BB
authors.lastname: Altunkeser
authors.forename: T
authors.initials: T
authors.lastname: Durmaz
authors.forename: E
authors.initials: E
authors.lastname: Altinyay
authors.forename: T
authors.initials: T
authors.lastname: Kural
authors.forename: S
authors.initials: S
authors.lastname: Korkmaz
authors.forename: M
authors.initials: M
authors.lastname: Kir
authors.forename: E
authors.initials: E
authors.lastname: Kütük
authors.forename: S
authors.initials: S
authors.lastname: Göksel
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure; D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis* / Q000000981:diagnostic imaging; D004280:Dobutamine; D004452:Echocardiography; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D004280:Dobutamine; D017256:Technetium Tc 99m Sestamibi