Dermatitis herpetiformis cured by hormone replacement for panhypopituitarism.
Dermatitis herpetiformis is an autoimmune skin disorder frequently associated with gastrointestinal diseases. We report a 53-year-old male with a four-year history of refractory dermatitis herpetiformis associated with hypopituitarism. Endocrine testing, ophthalmological examination and magnetic resonance imaging revealed hypopituitarism due to a non-functioning pituitary macroadenoma. Following transsphenoidal removal of the pituitary tumor and appropriate hormone replacement, complete remission of the skin disorder was obtained. We discuss the permissive role of panhypopituitarism in the course of dermatitis herpetiformis.
Spitzweg
C
C
Division of Endocrinology, Medizinische Klinik, Klinikum Innenstadt Ludwig-Maximilians-University, Munich, Germany.
Hofbauer
L C
LC
Heufelder
A E
AE
D000236:Adenoma / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D003874:Dermatitis Herpetiformis / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D007018:Hypopituitarism / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D013739:Testosterone / Q000627:therapeutic use; D013974:Thyroxine / Q000627:therapeutic use
D013739:Testosterone; D013974:Thyroxine; D006854:Hydrocortisone