title: [Clinical and immunological features of peripheral uveitis in children and adolescents. Differentiated treatment strategy].
abstract: Sixty-eight children with peripheral uveitis (PU) were examined, which is 11.5% of the total number of children with endogenous uveitis. In addition to the classical signs of PU, children often develop papillitis, corneal precipitations, and diffuse cataracts which are formed early. Clinical and immunological correlations were revealed, indicating a relationship between the clinical features and the disease etiology and pathogenesis: herpetic forms of PU (infectious and infectious-allergic) with immunopathological reactions to the retinal S-antigen only during late stages when the process takes a chronic course. Differentiated treatment strategy of PU with due consideration for the detected features is proposed.
authors.affiliation: Moscow NII of Eye Diseases.
authors.forename: L A
authors.initials: LA
authors.lastname: Katargina
authors.forename: O S
authors.initials: OS
authors.lastname: Slepova
authors.forename: G I
authors.initials: GI
authors.lastname: Krichevskaia
authors.forename: A V
authors.initials: AV
authors.lastname: Khvatova
authors.forename: G N
authors.initials: GN
authors.lastname: Bykovskaia
mesh_terms: D000293:Adolescent; D000998:Antiviral Agents / Q000627:therapeutic use; D019393:Arrestin / Q000276:immunology; D002648:Child; D002908:Chronic Disease; D003228:Conjunctiva / Q000821:virology; D017679:Cryotherapy; D003657:Decision Making; D015828:Eye Infections, Viral / Q000209:etiology* / Q000628:therapy; D005260:Female; D006801:Humans; D017075:Laser Coagulation; D008297:Male; D012160:Retina / Q000276:immunology / Q000821:virology; D014605:Uveitis / Q000276:immunology / Q000628:therapy / Q000821:virology; D014821:Vitrectomy
chemical_list: D000998:Antiviral Agents; D019393:Arrestin