The development of the growth plate after birth: a study by osteocalcin immunocytochemistry.
The post natal development of the growth plate was studied in the rabbit lower limb using an immunocytochemical technique which localized osteocalcin in situ. At birth, there is poor columnar organization of the physis and bone is not produced. Instead the predominant activity is cartilage remodelling. The columnar architecture develops later when endochondral ossification is also observed.
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Glenfield Hospital, Leicester, UK.
D000375:Aging / Q000378:metabolism; D000818:Animals; D005269:Femur / Q000033:anatomy & histology; D006132:Growth Plate / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism; D007150:Immunohistochemistry; D015675:Osteocalcin / Q000378:metabolism*; D010012:Osteogenesis; D011817:Rabbits; D013977:Tibia / Q000033:anatomy & histology
D015675:Osteocalcin