title: Solid and papillary tumor of the pancreas: ultrastructural observations on two contrasting cases.
abstract: Two papillary and solid tumors of the pancreas are reported which differed in their clinical features, ultrastructure, and biologic behavior. Both tumors contained papillary and solid areas by light microscopy. One tumor followed the more usual indolent course. The second patient presented with a liver metastasis and died of progressive disease in a relatively short period of time. Neither neoplasm showed convincing immunohistochemical or ultrastructural evidence of endocrine differentiation, but the electron microscopic findings hinted that this tumor possesses at least latent endocrine properties.
authors.affiliation: Department of Pathology, University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.
authors.forename: G
authors.initials: G
authors.lastname: de la Roza
authors.forename: K R
authors.initials: KR
authors.lastname: Cleary
authors.forename: N G
authors.initials: NG
authors.lastname: Ordóñez
authors.forename: A
authors.initials: A
authors.lastname: el-Naggar
authors.forename: B
authors.initials: B
authors.lastname: Mackay
authors.forename: M M
authors.initials: MM
authors.lastname: Romsdahl
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000032:analysis; D001706:Biopsy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000737:chemistry / Q000473:pathology*; D011003:Ploidies; D012186:Retroperitoneal Neoplasms / Q000737:chemistry / Q000473:pathology*
chemical_list: D015415:Biomarkers