Dengue haemorrhagic fever/dengue shock syndrome. An unwelcome arrival in Trinidad.
This is the first report of dengue haemorrhagic fever and dengue shock syndrome in Trinidad. Dengue infection was confirmed serologically or by viral isolation in five patients, aged 15 to 53 years, who presented with fever, thrombocytopenia and haemoconcentration. Three patients developed dengue shock syndrome, which was fatal; although there was no haemorrhagic tendency among these patients, bleeding occurred shortly before death in one of them. Two patients who had dengue haemorrhagic fever survived. The co-circulation of dengue virus serotypes 1, 2, and 4 in the Caribbean facilitates the development of dengue shock syndrome (DSS) or dengue haemorrhagic fever (DHF). Clinicians should therefore be aware of their clinical features, laboratory diagnosis and clinical management. Appropriate public health interventions and improved surveillance should be implemented to reduce the risk of DHF/DSS associated mortality in Trinidad and Tobago.
Teelucksingh
S
S
Department of Medicine, Eric Williams Medical Sciences Complex, Trinidad.
Mangray
A S
AS
Barrow
S
S
Jankey
N
N
Prabhakar
P
P
Lewis
M
M
D000293:Adolescent; D000328:Adult; D003715:Dengue / Q000175:diagnosis* / Q000401:mortality; D003716:Dengue Virus / Q000145:classification; D003906:Developing Countries; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D015996:Survival Rate; D014300:Trinidad and Tobago / Q000453:epidemiology