Pincer nails and alopecia as markers of gastrointestinal malignancy.
Nail abnormalities may be markers of non-dermatologic disease. We present a case in which pronounced pincer nails and universal alopecia developed in association with a metastasising adenocarcinoma of the sigmoid colon. It is suggested that this association represents a new ectodermal paraneoplastic syndrome.
Jemec
G B
GB
Department of Dermatology, Rigshospitalet, University of Copenhagen, Denmark.
Thomsen
K
K
D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis / Q000556:secondary; D000368:Aged; D000505:Alopecia / Q000209:etiology / Q000473:pathology*; D003110:Colonic Neoplasms / Q000150:complications / Q000175:diagnosis; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D009264:Nails, Malformed / Q000209:etiology / Q000473:pathology*; D010257:Paraneoplastic Syndromes / Q000175:diagnosis