[The use of cefotetan for the prevention of infectious postoperative complications in gynecology].
The study presents the results from the use of cefotetan for perioperative prophylaxis in 43 gynaecology patients compared with 29 controls without perioperative antibiotic prophylaxis with similar diseases and operations. Both groups show equal percentage of the cases with smooth postoperative period (70 and 72% respectively). 13 of the patients on cefotetan prophylaxis received additional antibiotic treatment (9 because of temperature up to 37.5 degrees and 4 because of temperature from 37.6 to 38.5 degrees). Mo major infections postoperative complications occurred among the patients on cefotetan prophylaxis. 8 of the non-prophylacted patients needed antibiotic treatment postoperatively including 4 with temperature above 38.5 degrees. Two infections of the operative wounds also occurred in the same group. The conclusion is that cefotetan effectively prevents the major infection postoperative complications in gynaecology. The administration of additional antibiotic treatment is most often not warranted.
Doganov
N
N
Dimitrov
R
R
Marinov
B
B
Shtereva
K
K
Nachev
A
A
Bozhilov
D
D
Blagoeva
V
V
D000293:Adolescent; D000328:Adult; D000368:Aged; D019072:Antibiotic Prophylaxis; D015313:Cefotetan / Q000627:therapeutic use*; D002513:Cephamycins / Q000627:therapeutic use*; D005260:Female; D005831:Genital Diseases, Female / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D011446:Prospective Studies; D013530:Surgical Wound Infection / Q000517:prevention & control*
D002513:Cephamycins; D015313:Cefotetan