Factors influencing antibody responses to acellular pertussis vaccines.
There are several factors which can potentially affect the immune response of humans to vaccination with acellular pertussis vaccines. The only way to study these responses at present is by serology. Only for a few of these factors has the effect on humoral immunogenicity been studied in any way, making conclusions difficult. Nonetheless, at least gender and pre-existing, maternal antibody appear not to influence the serological response to acellular pertussis vaccination.
Trollfors
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Department of Paediatrics, Gothenburg University, Sweden.
D018829:Adhesins, Bacterial / Q000276:immunology; D000907:Antibodies, Bacterial / Q000096:biosynthesis* / Q000276:immunology; D000942:Antigens, Bacterial / Q000276:immunology; D001425:Bacterial Outer Membrane Proteins / Q000276:immunology; D015721:Diphtheria-Tetanus-Pertussis Vaccine / Q000276:immunology*; D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines; D005260:Female; D010861:Fimbriae, Bacterial / Q000276:immunology; D006388:Hemagglutinins / Q000276:immunology; D006801:Humans; D007115:Immunization Schedule; D008297:Male; D014611:Vaccination; D010566:Virulence Factors, Bordetella; D014917:Whooping Cough / Q000517:prevention & control
D018829:Adhesins, Bacterial; D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001425:Bacterial Outer Membrane Proteins; D015721:Diphtheria-Tetanus-Pertussis Vaccine; D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines; D006388:Hemagglutinins; D010566:Virulence Factors, Bordetella; C065273:filamentous hemagglutinin adhesin, Bordetella pertussis; C068929:pertactin