title: The dietary fatty acids of patients with coronary artery disease and controls in Curaçao. Implications for primary and secondary prevention.
abstract: Patients with coronary artery disease are advised to augment their dietary linoleic acid intakes at the expense of saturated fatty acids. We investigated whether the dietary linoleic acid intake of 57 patients with coronary artery disease (47 males, 10 females; ages 61 +/- 10 years) in Curaçao is higher as compared with 77 controls (51 males, 26 females; ages 56 +/- 7 years). For this, we measured plasma cholesterol ester fatty acids, which reflect the dietary fatty acid composition of the preceding weeks. Patients with coronary artery disease and controls had minor differences in cholesterol ester fatty acids. Their cholesterol ester linoleic acid content suggests that the dietary polyunsaturated/saturated fatty acid ratio is far below 1. Comparison with data reported for The Netherlands, Greenland and Crete showed that the dietary fatty acid composition in Curaçao is typically Western with a high intake of saturated fatty acids, a low intake of monounsaturated fatty acids and the consumption of linoleic acid as the predominant polyunsaturated fatty acid. Intake of long chain polyunsaturated fatty acids from fatty fish is low. Reduction of dietary saturated fatty acids, augmentation of fish consumption, and an increase of the alpha-linolenic/linoleic acid ratio are likely to be of benefit to both primary and secondary prevention from coronary artery disease in Curaçao.
authors.affiliation: Central Laboratory for Clinical Chemistry, University Hospital Gröningen, The Netherlands.
authors.forename: D A
authors.initials: DA
authors.lastname: Brouwer
authors.forename: F P
authors.initials: FP
authors.lastname: van der Dijs
authors.forename: C B
authors.initials: CB
authors.lastname: Leerink
authors.forename: H N
authors.initials: HN
authors.lastname: Steward
authors.forename: T A
authors.initials: TA
authors.lastname: Kroon
authors.forename: G H
authors.initials: GH
authors.lastname: Suverkropp
authors.forename: J W
authors.initials: JW
authors.lastname: Römer
authors.forename: J J
authors.initials: JJ
authors.lastname: van Doormaal
authors.forename: F A
authors.initials: FA
authors.lastname: Muskiet
mesh_terms: D000328:Adult; D000368:Aged; D002788:Cholesterol Esters / Q000097:blood; D003327:Coronary Disease / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D004041:Dietary Fats / Q000008:administration & dosage* / Q000009:adverse effects; D005227:Fatty Acids / Q000008:administration & dosage* / Q000009:adverse effects / Q000097:blood; D005247:Feeding Behavior; D005260:Female; D005395:Fish Oils / Q000008:administration & dosage; D006801:Humans; D019787:Linoleic Acid; D008041:Linoleic Acids / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D014505:Urban Population; D014687:Venezuela
chemical_list: D002788:Cholesterol Esters; D004041:Dietary Fats; D005227:Fatty Acids; D005395:Fish Oils; D008041:Linoleic Acids; D019787:Linoleic Acid