title: [Ultrasound-guided fine-needle aspiration biopsy of focal liver lesions].
abstract: The ultrasound guided percutaneous fine needle biopsy (US-FNAB) of focal lesions in the liver is indispensable in many clinical situations. During the last 12 years, 657 US-FNAB were performed on patients with suspected neoplastic involvement of the liver with 22-gauge Chiba needles at our department. US-FNAB was performed mostly with the "free hand" technique. Sufficient material for cytologic analysis was obtained in 84% of the cases. The biopsies confirmed malignancy in 39.3%, including 9% primary hepatocellular carcinoma, 8% of the cases were suspect for malignancy, and in 36.7% were diagnosed benign lesion. 233 cases were confirmed histologically and with other follow up methods. The sensitivity rate was 91%, and specificity was 100%. There was no false positive diagnosis and no noteworthy complications were observed. US-FNAB is a highly reliable, safe, inexpensive and easy diagnostic procedure. On the basis of our experience, we recommend US-FNAB as a routine, first level procedure for the diagnosis of focal liver diseases.
authors.affiliation: Semmelweis Orvostudományi Egyetem, Budapest, II. Patológiai Intézet.
authors.forename: B
authors.initials: B
authors.lastname: Járay
authors.forename: E
authors.initials: E
authors.lastname: Turányi
authors.forename: K
authors.initials: K
authors.lastname: Szalay
authors.forename: T
authors.initials: T
authors.lastname: Winternitz
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D001707:Biopsy, Needle / Q000295:instrumentation*; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging* / Q000473:pathology; D003110:Colonic Neoplasms / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary; D014463:Ultrasonography