title: Simultaneous identification of campylobacters and prediction of quinolone resistance by comparative sequence analysis.
abstract: Comparative sequence analysis of a 30-bp segment in the quinolone resistance-determining region of campylobacters not only allows for the detection of base changes associated with resistance but also is a powerful tool for species identification based on silent mutations.
authors.affiliation: Institute for Medical Microbiology and Hygiene, Johannes-Gutenberg-University Mainz, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Husmann
authors.forename: A
authors.initials: A
authors.lastname: Feddersen
authors.forename: A
authors.initials: A
authors.lastname: Steitz
authors.forename: C
authors.initials: C
authors.lastname: Freytag
authors.forename: S
authors.initials: S
authors.lastname: Bhakdi
mesh_terms: D042462:4-Quinolones; D000890:Anti-Infective Agents / Q000494:pharmacology*; D002167:Campylobacter / Q000187:drug effects* / Q000235:genetics*; D027081:DNA Gyrase; D004250:DNA Topoisomerases, Type II / Q000235:genetics*; D004269:DNA, Bacterial / Q000032:analysis*; D004352:Drug Resistance, Microbial / Q000235:genetics; D016133:Polymerase Chain Reaction; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity
chemical_list: D042462:4-Quinolones; D000890:Anti-Infective Agents; D004269:DNA, Bacterial; D027081:DNA Gyrase; D004250:DNA Topoisomerases, Type II