12,13-isotaxanes: synthesis of new potent analogs and X-ray crystallographic confirmation of structure.
Johnson
R A
RA
Research Laboratories, Pharmacia & Upjohn, Inc., Kalamazoo, Michigan 49001, USA.
Dobrowolski
P J
PJ
Nidy
E G
EG
Gebhard
I
I
Qualls
S J
SJ
Wicnienski
N A
NA
Kelly
R C
RC
Pitts
T W
TW
Lopes
N M
NM
DeKoning
T F
TF
Mattern
S J
SJ
Weed
S D
SD
McGovren
J P
JP
Chidester
C G
CG
D000470:Alkaloids / Q000138:chemical synthesis / Q000737:chemistry / Q000633:toxicity; D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D001952:Bridged-Ring Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D018360:Crystallography, X-Ray; D005260:Female; D006801:Humans; D008546:Melanoma, Experimental / Q000188:drug therapy; D051379:Mice; D008815:Mice, Inbred Strains; D008968:Molecular Conformation; D015394:Molecular Structure; D010051:Ovarian Neoplasms; D017239:Paclitaxel / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D043823:Taxoids; D014407:Tumor Cells, Cultured
D000470:Alkaloids; D000970:Antineoplastic Agents; D001952:Bridged-Ring Compounds; D043823:Taxoids; C080625:taxane; D017239:Paclitaxel