title: [Influence of lead on metabolism of vitamins B group in alimentary iron deficient rats].
abstract: Experimentally induced lead poisoning especially under simultaneous iron deficit leads to the development of secondary thiamine insufficiency. Erythrocyte riboflavin content and erythrocyte glutathion reductase and aspartate aminotransferase activities have been demonstrated to be increased. Lead treatment is accompanied with the increase of urinary excretion of riboflavin, 4-pyridoxic acid and 1-vtthylnicotinamide in rats fed with adequate diet. Thus lead intoxication and iron deficiency influence vitamin B group metabolism.
authors.affiliation: Institute of Nutrition RAMN, Moscow.
authors.forename: S A
authors.initials: SA
authors.lastname: Khotimchenko
authors.forename: V M
authors.initials: VM
authors.lastname: Kodentsova
authors.forename: I A
authors.initials: IA
authors.lastname: Alekseeva
authors.forename: S G
authors.initials: SG
authors.lastname: Vlaskina
authors.forename: O A
authors.initials: OA
authors.lastname: Vrzhesinskaia
authors.forename: A A
authors.initials: AA
authors.lastname: Sokol'nikov
authors.forename: L A
authors.initials: LA
authors.lastname: Kharitonchik
authors.forename: I P
authors.initials: IP
authors.lastname: Aleshko-Ozhevskií
authors.forename: L V
authors.initials: LV
authors.lastname: Sheviakova
mesh_terms: D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism; D005980:Glutathione Reductase / Q000097:blood; D000090463:Iron Deficiencies; D007855:Lead Poisoning / Q000150:complications / Q000378:metabolism*; D008297:Male; D009536:Niacinamide / Q000031:analogs & derivatives / Q000652:urine; D011735:Pyridoxic Acid / Q000652:urine; D051381:Rats; D012256:Riboflavin / Q000097:blood / Q000652:urine; D013831:Thiamine / Q000097:blood / Q000652:urine; D013832:Thiamine Deficiency / Q000097:blood / Q000209:etiology / Q000652:urine; D014803:Vitamin B Complex / Q000378:metabolism*
chemical_list: D014803:Vitamin B Complex; D009536:Niacinamide; D011735:Pyridoxic Acid; D005980:Glutathione Reductase; D001219:Aspartate Aminotransferases; D012256:Riboflavin; C024058:N(1)-methylnicotinamide; D013831:Thiamine