title: [Intravascular coagulation as a typical concomitant of acute pulmonary tuberculosis].
abstract: Hemostasis and fibrinolysis, markers of intravascular coagulation (IC), hemorrhagic parameters, and platelet aggregatory properties were studied in 119 patients with various types of pulmonary tuberculosis. In patients with active pulmonary tuberculosis, IC was found to be a persistent and important component of a pathological process which both plasma factors and circulating cells were involved in. In most critical patients, the degree and rate of spontaneous and stimulated platelet aggregation were decreased, when stimulated, the rate of increases in the mean volume of aggregates was yet higher in these patients than in the controls. The latter created an additional prerequisite for progression of microthrombogenesis.
authors.affiliation: Central NII of Tuberculosis RAMN, Moscow.
authors.forename: G O
authors.initials: GO
authors.lastname: Kaminskaia
authors.forename: B A
authors.initials: BA
authors.lastname: Serebrianaia
authors.forename: E V
authors.initials: EV
authors.lastname: Martynova
authors.forename: V I
authors.initials: VI
authors.lastname: Mishin
mesh_terms: D000208:Acute Disease; D018450:Disease Progression; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000150:complications*; D006487:Hemostasis / Q000502:physiology*; D006801:Humans; D010974:Platelet Aggregation; D013923:Thromboembolism / Q000097:blood / Q000209:etiology; D014397:Tuberculosis, Pulmonary / Q000097:blood / Q000150:complications*