Terpenoids from Salvia glutinosa.
A new steroidal compound 1-oxo-7 alpha-hydroxysitosterol was isolated from the whole plant of Salvia glutinosa in addition to 11 known triterpenoids and three steroids. The structures were established by spectral data. Cytotoxic activity of the new compound and 7 alpha-hydroxysitosterol were tested against P-388 and KB systems; only marginal activity was found.
Topcu
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TUBITAK, Marmara Research Center, Department of Chemistry, Gebze- Kocaeli, Turkey.
Tan
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Kökdil
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Ulubelen
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D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D007624:KB Cells; D007941:Leukemia P388; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051379:Mice; D010946:Plants, Medicinal; D012855:Sitosterols / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D013053:Spectrophotometry; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D014407:Tumor Cells, Cultured; D014421:Turkey
C107211:1-oxo-7-hydroxysitosterol; D000972:Antineoplastic Agents, Phytogenic; D012855:Sitosterols; D013256:Steroids; D014315:Triterpenes