title: Scedosporium prolificans corneoscleritis: a successful outcome.
abstract: BACKGROUND
  A case of Scedosporium prolificans corneoscleritis is reported in a patient who had developed scleral necrosis following pterygium surgery, with adjunctive beta-irradiation. This fungus has been reported to be the causative organism in only two previous cases of corneoscleritis.
  
  
  METHODS
  The patient presented with signs and symptoms typical of corneoscleritis. When the fungus was isolated from a biopsy specimen, aggressive scleral debridement was carried out and intensive antifungal therapy was instigated.
  
  
  RESULTS
  After a prolonged course, the eye was rendered sterile.
  
  
  CONCLUSIONS
  Early conjunctival recession and aggressive scleral debridement combined with intensive instillation of antifungals are crucial to the successful management of fungal corneoscleritis.
authors.affiliation: Department of Ophthalmology, Royal Perth Hospital, Australia.
authors.forename: B
authors.initials: B
authors.lastname: Kumar
authors.forename: G J
authors.initials: GJ
authors.lastname: Crawford
authors.forename: G C
authors.initials: GC
authors.lastname: Morlet
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D001706:Biopsy; D003315:Cornea / Q000382:microbiology / Q000473:pathology; D003646:Debridement; D015821:Eye Infections, Fungal / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007634:Keratitis / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D003904:Mitosporic Fungi / Q000302:isolation & purification; D009181:Mycoses / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D009336:Necrosis; D011625:Pterygium / Q000532:radiotherapy / Q000601:surgery; D012590:Sclera / Q000382:microbiology / Q000473:pathology; D015423:Scleritis / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology
chemical_list: D000935:Antifungal Agents