Pharmacokinetics of [14C] BBR 3053, an alkylating bisphosphonate, after single i.v. and multiple s.c. administration in rats.
Bernareggi
A
A
Boehringer Mannheim Italia SpA, Centro Ricerche, Monza (MI).
Crippa
M T
MT
Bastrup
U
U
Di Giovine
S
S
Cesarini
R
R
Tognella
S
S
D000818:Animals; D018906:Antineoplastic Agents, Alkylating / Q000008:administration & dosage / Q000493:pharmacokinetics*; D002279:Carcinoma 256, Walker / Q000188:drug therapy / Q000378:metabolism; D004164:Diphosphonates / Q000008:administration & dosage / Q000493:pharmacokinetics*; D007275:Injections, Intravenous; D007279:Injections, Subcutaneous; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D014018:Tissue Distribution
D018906:Antineoplastic Agents, Alkylating; C108156:BBR 3053; D004164:Diphosphonates