Trigeminal perception of odorant quality in congenitally anosmic subjects.
Twenty congenitally anosmic subjects and 50 normosmic controls were tested for their ability (i) to assign verbal labels from a list of trigeminal-type descriptors to six odorants believed to have a strong trigeminal component; and (ii) to discriminate between intensity-matched pairs of these odorants in an odd-ball paradigm. The following was found: normosmic controls judged menthol and cineole as distinctly cool and fresh, acetic acid as pungent and sour, and acetone as pungent, but showed no clear descriptive profile for ethanol and propanol. The descriptive profiles given by the anosmic subjects correlated significantly with those given by the controls for three of the six odorants (menthol, cineol and ethanol), confirming that the sensations described may indeed be mediated by the trigeminal system. In the odd-ball test, the control subjects correctly identified an average of eight out of the nine items presented, with most mistakes occurring in response to pairs with a similar trigeminal profile. With an average of 7.2 of nine items correct, the performance of the anosmic subjects was not significantly different to that of the normosmics, except in discriminating between acetic acid and menthol. Although additional tests are necessary to decide finally whether differences in stimulus intensity may have contributed to this good discriminatory performance, the present results suggest that the nasal trigeminal system may contribute significantly to the perception of odor quality.
Laska
M
M
Institute für Medizinische Psychologie, Ludwig-Maximilians-Universität, München, Germany.
Distel
H
H
Hudson
R
R
D000433:1-Propanol / Q000494:pharmacology; D019342:Acetic Acid / Q000494:pharmacology; D000096:Acetone / Q000494:pharmacology; D000328:Adult; D003511:Cyclohexanols; D004192:Discrimination, Psychological / Q000187:drug effects / Q000502:physiology; D000431:Ethanol / Q000494:pharmacology; D000077591:Eucalyptol; D006801:Humans; D008610:Menthol / Q000031:analogs & derivatives / Q000494:pharmacology; D039821:Monoterpenes; D009812:Odorants; D000857:Olfaction Disorders / Q000151:congenital* / Q000503:physiopathology*; D010465:Perception / Q000187:drug effects / Q000502:physiology*; D012903:Smell / Q000187:drug effects / Q000502:physiology; D013729:Terpenes; D014276:Trigeminal Nerve / Q000503:physiopathology*
D003511:Cyclohexanols; D039821:Monoterpenes; D013729:Terpenes; D000096:Acetone; D008610:Menthol; D000431:Ethanol; D000433:1-Propanol; D019342:Acetic Acid; D000077591:Eucalyptol