title: [Morphologic analysis of congenital central nervous system malformations in children from the first of life dying in the years 1986-1990].
abstract: An incidence and morphology of the CNS congenital malformations in newborn babies and infants were analysed in the consecutive autopsies carried out in 1986-1990, i.e. following Tscharnobyl disaster. The obtained results were compared to those seen in the two earlier periods (1976-1980 and 1981-1986). In 1986-1990, a percentage of autopsies showing congenital CNS malformations increased approximately by two-fold (15%). The highest percentage of such malformations in specific years of the analysed period was noted in 1990 (20%). Central nervous system malformations were more frequent in female sex (57%) than in male sex (43%). In 64% of cases newborn babies were affected. A percentage of CNS malformations coexisting with other congenital malformations increased to 40% in the analysed period of time (from 29.4% in 1976-1985). Meningomyelocele (41%), congenital hydrocephalus (21.5%), multiple anomalies in brain (14%), and anencephaly (12.6%) constituted the most frequent group of CNS malformations. In 1986-1990, an incidence of meningomyelocele increased by more than two-fold (if this anomaly coexisted with hydrocephaly, an increase in the incidence exceeded three-fold), and hydrocephaly as well as an increase in the incidence of anencephaly by 1.5 times in comparison with 1976-1985.
authors.affiliation: Zakładu Anatomii Patologicznej AM w Białymstoku.
authors.forename: M
authors.initials: M
authors.lastname: Sobaniec-Lotowska
authors.forename: W
authors.initials: W
authors.lastname: Sobaniec
authors.forename: M
authors.initials: M
authors.lastname: Sulkowska
authors.forename: S
authors.initials: S
authors.lastname: Sulkowski
authors.forename: W
authors.initials: W
authors.lastname: Kułak
mesh_terms: D000015:Abnormalities, Multiple / Q000453:epidemiology* / Q000473:pathology*; D000059:Accidents; D001344:Autopsy; D002490:Central Nervous System / Q000002:abnormalities*; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009688:Nuclear Reactors; D011044:Poland / Q000453:epidemiology; D017678:Sex Distribution; D014455:Ukraine