title: Experience with segmental reconstruction of the radiated mandible with alloplastic prostheses.
abstract: Reconstruction of the mandible after radiation therapy and segmental resection is often complicated by wound breakdown, osteoradionecrosis, and crippling of the oral cavity. These complications make patient salvage after radiated oral carcinoma a high-risk endeavor. Although head and neck surgeons have improved the reliability of mandibular reconstruction with microvascular free tissue transfer, medical and oncologic issues may prohibit their application. This report presents 12 selected cases undergoing alloplastic reconstruction of the mandible and soft tissue reconstruction of the oral cavity. Although not as reliable as some reports of free tissue transfers, the results were reproducible and satisfactory in these cases, with time-efficient hospitalization and functional rehabilitation. Ten of 12 prosthetic reconstructions have been durable in this study population for as long as 36 months.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco-Mount Zion Cancer Center, 94115, U.S.A.
authors.forename: D
authors.initials: D
authors.lastname: Greene
authors.forename: S
authors.initials: S
authors.lastname: Sussman
authors.forename: M I
authors.initials: MI
authors.lastname: Singer
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D008334:Mandible / Q000601:surgery; D008336:Mandibular Diseases / Q000601:surgery; D008341:Mandibular Prosthesis; D008875:Middle Aged; D009062:Mouth Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D010025:Osteoradionecrosis / Q000601:surgery; D014025:Titanium
chemical_list: D014025:Titanium