Idiopathic thrombocytopenic purpura in pregnancy treated with pulsed high-dose oral dexamethasone.
Idiopathic thrombocytopenic purpura in pregnancy is usually treated with prednisone or intravenous immune globulin. Because of the fetal risk, there are few good alternatives for women who do not respond. We report a case of refractory idiopathic thrombocytopenic purpura successfully treated with pulsed high-dose oral dexamethasone, which offered ease of administration, low cost, and low risk.
Byrne
J D
JD
Department of Obstetrics and Gynecology, University of Southern California School of Medicine, Los Angeles, USA.
Incerpi
M H
MH
Goodwin
T M
TM
D000328:Adult; D003907:Dexamethasone / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000188:drug therapy*; D011256:Pregnancy Outcome; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000188:drug therapy*
D005938:Glucocorticoids; D003907:Dexamethasone