Sweat gland vacuoles in Unverricht-Lundborg disease.
We report a re-evaluation of skin biopsies of 4 patients with Unverricht-Lundborg (UL) disease showing membrane-bound bodies in sweat glands. The previously described findings in 5 patients by Cochius et al. (1994) are confirmed. The data suggest that skin biopsy may be a useful mean for confirmation of diagnosis in this disorder, but the specificity of these findings is to be proved by examination of a larger number of cases.
Federico
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D000293:Adolescent; D000328:Adult; D001706:Biopsy; D002648:Child; D003594:Cytoplasmic Granules / Q000648:ultrastructure*; D004831:Epilepsies, Myoclonic / Q000473:pathology*; D006801:Humans; D008854:Microscopy, Electron; D013545:Sweat Glands / Q000473:pathology* / Q000648:ultrastructure