[Role of PCR and dot bolt hybridization in the detection of human papillomavirus of the penile cancer].
Human papillomavirus (HPV), a oncogenicpotential, may be carcinogenic effectors in variety of genital tract malignancies. We examined the association of human papillomavirus type 16 and 18 in 28 penile cancers by the highly sensitive polymerase chain reaction and dot bolt hybridization. Human papillomavirus type 16 was found in 14 of 28 penile cancers (50%), whereas type 18 was identified in 3 of 28 penile cancers (10.6%). Our results suggest humanpapillomavirus type 16 may play a role in the development of this tumor and associate with smoking and ages of patients.
Ding
Q
Q
Huashan Hospital, Shanghai Medical University.
Zhang
Y
Y
Sun
S
S
D000328:Adult; D004279:DNA, Viral / Q000032:analysis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D027383:Papillomaviridae / Q000302:isolation & purification*; D030361:Papillomavirus Infections; D010412:Penile Neoplasms / Q000821:virology*; D016133:Polymerase Chain Reaction; D012189:Retrospective Studies; D014412:Tumor Virus Infections
D004279:DNA, Viral