title: Comparison of dobutamine ECG stress test with predischarge exercise test after acute myocardial infarction.
abstract: Exercise testing after acute myocardial infarction is commonly used, but in recent years alternative methods have been proposed. Standard exercise testing was compared with dobutamine electrocardiographic (ECG) stress testing in 100 patients after an acute initial myocardial infarction. Dobutamine ECG stress testing was performed in a standard manner at 5 +/- 1 days after the infarction and exercise testing was performed a mean of 10 +/- 2 days following the event. Agreement between both tests was observed in 91 cases (91%), P < .001, Fisher test kappa value, 0.79). The dobutamine test predicted the result of the exercise test with a sensitivity of 100% (95% confidence interval, 87-100) and a specificity of 88% (95% confidence interval 77-93) for a positive predictive value of 75% (95% confidence interval, 62-97) and a negative predictive value of 100% (95% confidence interval, 91-100). Dobutamine ECG stress testing is concluded to be an objective and reliable procedure, which accurately predicts the results of standard exercise testing. It is inexpensive, easy to perform, and although not yet confirmed, could be particularly useful in patients who cannot perform exercise.
authors.affiliation: Division of Coronary Care, Hospital de Clinicas José de San Martín, University of Buenos Aires School of Medicine, Argentina.
authors.forename: J A
authors.initials: JA
authors.lastname: Martínez-Martínez
authors.forename: C
authors.initials: C
authors.lastname: Militello
authors.forename: V
authors.initials: V
authors.lastname: Irazola
authors.forename: R
authors.initials: R
authors.lastname: Perez de la Hoz
authors.forename: J
authors.initials: J
authors.lastname: Lerman
authors.forename: E
authors.initials: E
authors.lastname: Sampó
mesh_terms: D000368:Aged; D004280:Dobutamine / Q000009:adverse effects / Q000494:pharmacology*; D004562:Electrocardiography / Q000379:methods*; D005080:Exercise Test / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000503:physiopathology*; D010351:Patient Discharge; D011237:Predictive Value of Tests; D011446:Prospective Studies
chemical_list: D004280:Dobutamine