title: Atrophic fundus lesions associated with untreated retinopathy of prematurity.
abstract: OBJECTIVE
  To document that lacunar, atrophic lesions of the retinal pigment epithelium, previously reported as a complication of treatment, can result from the natural course of retinopathy of prematurity.
  
  
  METHODS
  We reviewed photographs of patients diagnosed with retinopathy of prematurity at the Casey Eye Institute between 1979 and 1996. Lacunar atrophic lesions of the retinal pigment epithelium were correlated with the clinical records of the affected patients.
  
  
  RESULTS
  Three untreated eyes of three patients with retinopathy of prematurity had lacunar atrophic lesions of the retinal pigment epithelium.
  
  
  CONCLUSIONS
  The spectrum of findings associated with untreated retinopathy of prematurity includes lacunar, atrophic lesions of the retinal pigment epithelium. These lesions are distinct from scars secondary to treatment and are possibly linked to macular dragging and exudative or serous retinal detachment.
authors.affiliation: Department of Ophthalmology, Casey Eye Institute, Oregon Health Sciences University, Portland 97201-4197, USA.
authors.forename: B C
authors.initials: BC
authors.lastname: Fishburne
authors.forename: K L
authors.initials: KL
authors.lastname: Winthrop
authors.forename: J E
authors.initials: JE
authors.lastname: Robertson
mesh_terms: D000328:Adult; D001284:Atrophy; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010857:Pigment Epithelium of Eye / Q000473:pathology; D012178:Retinopathy of Prematurity / Q000473:pathology*