Abnormal technetium labelled white cell scan in the colitis of chronic granulomatous disease.
A child with colitis was treated for Crohn's disease, diagnosed on history, clinical and colonoscopic findings, radiolabelled white cell bowel scan, and colonic histology. After septicaemia caused by an unusual organism, further investigation lead to a diagnosis of chronic granulomatous disease (CGD). The granulomatous colitis of CGD is clinically, histologically, and on white cell scanning, indistinguishable from that in Crohn's disease and should be considered in atypical cases. Infection with unusual 'pseudomonads' should prompt the exclusion of this disorder.
Hoare
S
S
Paediatric Department, Newcastle General Hospital, Westgate Road, Newcastle upon Tyne.
Walsh
J E
JE
Eastham
E
E
Abinun
M A
MA
Cant
A J
AJ
D019121:Burkholderia Infections / Q000000981:diagnostic imaging* / Q000473:pathology; D002675:Child, Preschool; D003092:Colitis / Q000000981:diagnostic imaging* / Q000382:microbiology; D003424:Crohn Disease / Q000000981:diagnostic imaging / Q000473:pathology; D003937:Diagnosis, Differential; D006105:Granulomatous Disease, Chronic / Q000000981:diagnostic imaging* / Q000382:microbiology; D006801:Humans; D007962:Leukocytes / Q000000981:diagnostic imaging*; D008297:Male; D015609:Organotechnetium Compounds; D010091:Oximes; D011877:Radionuclide Imaging; D019690:Technetium Tc 99m Exametazime
D015609:Organotechnetium Compounds; D010091:Oximes; D019690:Technetium Tc 99m Exametazime