title: DIAS--the diabetes advisory system: an outline of the system and the evaluation results obtained so far.
abstract: The present paper gives a description of the Diabetes Advisory System (DIAS), and the evaluation results obtained so far. DIAS is a decision support system for the management of insulin dependent diabetes. The core of the system is a compartment model of the human carbohydrate metabolism implemented as a causal probabilistic network (CPN or Bayesian network), which gives it the ability to handle the uncertainty, for example, in blood glucose measurements or physiological variations in glucose metabolism. The evaluation results suggest that, at least in our hands, DIAS can generate advice that is safe and of a quality that is at least comparable to what is available from experienced clinicians.
authors.affiliation: Department of Medical Informatics, Aalborg University, Denmark. okh@miba.auc.dk
authors.forename: O K
authors.initials: OK
authors.lastname: Hejlesen
authors.forename: S
authors.initials: S
authors.lastname: Andreassen
authors.forename: R
authors.initials: R
authors.lastname: Hovorka
authors.forename: D A
authors.initials: DA
authors.lastname: Cavan
mesh_terms: D001499:Bayes Theorem; D001786:Blood Glucose / Q000032:analysis / Q000378:metabolism; D003198:Computer Simulation; D003660:Decision Support Systems, Management; D003922:Diabetes Mellitus, Type 1 / Q000188:drug therapy* / Q000378:metabolism; D004040:Dietary Carbohydrates / Q000378:metabolism; D004360:Drug Therapy, Computer-Assisted; D005069:Evaluation Studies as Topic; D005103:Expert Systems; D005947:Glucose / Q000378:metabolism; D006442:Glycated Hemoglobin / Q000032:analysis / Q000378:metabolism; D006801:Humans; D007003:Hypoglycemia / Q000097:blood / Q000209:etiology; D007328:Insulin / Q000008:administration & dosage / Q000627:therapeutic use; D007408:Intestinal Absorption; D008954:Models, Biological; D016571:Neural Networks, Computer; D011336:Probability
chemical_list: D001786:Blood Glucose; D004040:Dietary Carbohydrates; D005947:Glucose; D006442:Glycated Hemoglobin; D007328:Insulin