title: Phylogenetic relationships of fungal cytochromes c.
abstract: The CYC1 gene encoding cytochrome c in the yeast Candida albicans was cloned by complementation of a cytochrome c-deficient mutant of Saccharomyces cerevisiae, and its DNA sequence was determined. The analysis of the amino acid sequences of cytochrome c from 14 fungal species and two isoforms from S. cerevisiae revealed sequences unique to fungi, and revealed a phylogenetic relationship with a pronounced divergence between Schizosaccharomyces pombe and other ascomycetous budding yeast.
authors.affiliation: Department of Biochemistry and Biophysics, University of Rochester Medical School, New York 14642, USA.
authors.forename: G
authors.initials: G
authors.lastname: Janbon
authors.forename: E P
authors.initials: EP
authors.lastname: Rustchenko
authors.forename: S
authors.initials: S
authors.lastname: Klug
authors.forename: S
authors.initials: S
authors.lastname: Scherer
authors.forename: F
authors.initials: F
authors.lastname: Sherman
mesh_terms: D000595:Amino Acid Sequence; D002176:Candida albicans / Q000201:enzymology; D003574:Cytochrome c Group / Q000737:chemistry / Q000235:genetics*; D004271:DNA, Fungal / Q000737:chemistry; D005658:Fungi / Q000145:classification / Q000201:enzymology*; D008969:Molecular Sequence Data; D010802:Phylogeny; D012441:Saccharomyces cerevisiae / Q000201:enzymology; D012568:Schizosaccharomyces / Q000201:enzymology
chemical_list: D003574:Cytochrome c Group; D004271:DNA, Fungal