title: [A clinical study of the efficacy of and tolerance for the combined transdermal preparation Estracomb TTS (CIBA)].
abstract: Result from the first study, carried out in our country an the therapeutic effects of Estracomb TTS in women with peri- and postmenopausal symptoms are reported. Seven women with postcastration syndrome and eight women with an intact uterus and no vaginal bleeding for a least 6 months were treated. In all women enrolled in the study the application of the preparation Estracomb TTS led to a significant improvement of peri- and postmenopausal symptoms without serious side effects.
authors.forename: S
authors.initials: S
authors.lastname: Tanchev
authors.forename: S
authors.initials: S
authors.lastname: Slaveĭkov
mesh_terms: D000279:Administration, Cutaneous; D004338:Drug Combinations; D004361:Drug Tolerance; D004958:Estradiol / Q000008:administration & dosage* / Q000009:adverse effects; D015914:Estrogen Replacement Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009640:Norethindrone / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D000077563:Norethindrone Acetate; D010052:Ovariectomy; D017698:Postmenopause / Q000187:drug effects; D017697:Premenopause / Q000187:drug effects; D013577:Syndrome; D013997:Time Factors
chemical_list: D004338:Drug Combinations; D004958:Estradiol; D000077563:Norethindrone Acetate; D009640:Norethindrone