title: Successful controlled limb reperfusion after severe prolonged ischemia.
abstract: Controlled limb reperfusion was performed in two patients who were admitted for lower limb-threatening ischemia as a result of embolism. After embolectomy, the inflow blood was drained with a cannula and mixed with a crystalloid solution to obtain an hyperosmolar, hypocalcemic, alkalotic, and substrate-enriched (aspartate, glutamate) reperfusate. This reperfusate was reinjected with a roller pump for 30 minutes through two cannulas inserted in the profunda and superficial femoral arteries. Temperature, intraarterial pressures, and flow were closely controlled. No complications occurred, and complete recovery of motor and sensory functions were observed, with restoration of pedal pulses.
authors.affiliation: Department of Cardiovascular Surgery, University Hospital of Liege, Belgium.
authors.forename: J O
authors.initials: JO
authors.lastname: Defraigne
authors.forename: J
authors.initials: J
authors.lastname: Pincemail
authors.forename: C
authors.initials: C
authors.lastname: Laroche
authors.forename: F
authors.initials: F
authors.lastname: Blaffart
authors.forename: R
authors.initials: R
authors.lastname: Limet
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007511:Ischemia / Q000601:surgery*; D007866:Leg / Q000098:blood supply*; D015424:Reperfusion / Q000379:methods*; D012720:Severity of Illness Index; D013997:Time Factors