Double minute chromosomes and myelodysplastic syndrome: a case report and literature review.
Double minute chromosomes (dmin) occur in about 3.3-10.6% of acute leukemia, especially in the elderly. However, dmins are relatively rare in myelodysplastic syndrome (MDS). We describe a case of refractory anemia with excess blasts associated with complex cytogenetic abnormalities, dmins, and brief survival.
Keung
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YK
Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock 79430, USA.
Cobos
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Morgan
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Whitehead
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Tonk
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D000368:Aged; D002869:Chromosome Aberrations / Q000235:genetics* / Q000473:pathology; D002871:Chromosome Banding; D025063:Chromosome Disorders; D005260:Female; D005784:Gene Amplification; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000235:genetics* / Q000473:pathology