title: Invasive versus non-invasive diagnosis of renal bone disease.
abstract: At present, bone histomorphometry remains the gold standard for the diagnosis of the various types of renal bone disease. In the search for a non-invasive method of diagnosis, biochemical serum markers of bone remodelling, in addition to serum intact parathyroid hormone and aluminium determinations, have been proposed as the most reliable tools and are at present widely used in clinical practice. Their respective diagnostic values, as separate items and in combined analysis, are thoroughly discussed in the present review.
authors.affiliation: Department of Nephrology, Amiens-University Hospital, France. neph-chu@burotec.fr
authors.forename: A
authors.initials: A
authors.lastname: Fournier
authors.forename: R
authors.initials: R
authors.lastname: Oprisiu
authors.forename: S
authors.initials: S
authors.lastname: Said
authors.forename: A
authors.initials: A
authors.lastname: Sechet
authors.forename: A
authors.initials: A
authors.lastname: Ghazali
authors.forename: A
authors.initials: A
authors.lastname: Marié
authors.forename: I
authors.initials: I
authors.lastname: el Esper
authors.forename: M
authors.initials: M
authors.lastname: Brazier
authors.forename: J M
authors.initials: JM
authors.lastname: Achard
authors.forename: P
authors.initials: P
authors.lastname: Morinière
mesh_terms: D000535:Aluminum / Q000097:blood; D015415:Biomarkers / Q000097:blood; D001847:Bone Diseases / Q000097:blood / Q000150:complications* / Q000175:diagnosis*; D001851:Bone Diseases, Metabolic / Q000097:blood / Q000209:etiology; D016723:Bone Remodeling / Q000502:physiology; D002114:Calcinosis / Q000097:blood / Q000209:etiology; D005357:Fibrous Dysplasia of Bone / Q000175:diagnosis; D006801:Humans; D006934:Hypercalcemia / Q000097:blood / Q000209:etiology; D007674:Kidney Diseases / Q000097:blood / Q000150:complications* / Q000175:diagnosis*; D010018:Osteomalacia / Q000175:diagnosis; D010281:Parathyroid Hormone / Q000097:blood; D010710:Phosphates / Q000097:blood
chemical_list: D015415:Biomarkers; D010281:Parathyroid Hormone; D010710:Phosphates; D000535:Aluminum