title: Erythrocyte carbonic anhydrase activity in smokers and in diabetic patients.
abstract: Carbonic anhydrase activity was measured in lyzed erythrocytes from smoking and non-smoking young men as well as from diabetic and healthy young women. Enzyme activity was determined by a changing-pH-assay, using a stirred reaction vessel and glass pH electrode. CAA was lower in smokers than in non-smokers. Furthermore, it was lower in diabetics than in nondiabetic controls. We conclude that cigarette smoking as well as diabetes mellitus may reduce erythrocyte carbonic anhydrase activity.
authors.affiliation: Institute of Physiology, Ernst-Moritz-Arndt-University Greifswald, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Abel
authors.forename: S
authors.initials: S
authors.lastname: Wussow
authors.forename: H
authors.initials: H
authors.lastname: Blücher
authors.forename: G
authors.initials: G
authors.lastname: Gros
authors.forename: R
authors.initials: R
authors.lastname: Rettig
authors.forename: A
authors.initials: A
authors.lastname: Honig
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000201:enzymology*; D004563:Electrochemistry / Q000379:methods; D004912:Erythrocytes / Q000201:enzymology*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D008297:Male; D012016:Reference Values; D012907:Smoking / Q000097:blood / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000097:blood*
chemical_list: D013482:Superoxide Dismutase