title: [A new method in the determination of individual delay time in bolus application in spiral CT].
abstract: Helical-CT examinations, particularly CT angiography, require precise timing between the examination procedure and the individual dynamics of contrast medium distribution in the arteriovenous system of the patient. The necessary delay between contrast medium injection and onset of has usually been either estimated or determined by means of an additional helical CT examination. The present paper introduces a new technique which allows bolus analysis without an additional scan. Prior to a CT angiography with 10 patients, two techniques for bolus analysis (BA) were compared. Prior to diagnostic contrast medium enhanced examination, a native (BA I) and a dynamic (BA II) examination were performed. Ten seconds prior to the start of each examination, a 10 ml test bolus was applied with an injection flow rate of 3 ml/s. Both examinations lasted for 30 s. During BA I, increase in attenuation in the aorta was compared at different sites, during BA II consistently at the same site. Comparison of the individual peak times yielded a coefficient of correlation of r = 0.926. The median value for BA I was 18.4 +/- 5.4 s and 19.2 +/- 4.5 s for BA II. The difference between measurement of peak time was 1.2 +/- 1.16 s. This modified technique for bolus analysis during the primary native scan of the upper abdominal organs permits calculation of the required individual delay time between contrast medium application and scan start: no additional examination is required and the method can be performed with any helical CT unit.
authors.affiliation: Radiologische Klinik und Poliklinik, Universität Ulm.
authors.forename: R
authors.initials: R
authors.lastname: Sokiranski
authors.forename: K
authors.initials: K
authors.lastname: Elsner
authors.forename: M
authors.initials: M
authors.lastname: Welke
authors.forename: J
authors.initials: J
authors.lastname: Görich
authors.forename: N
authors.initials: N
authors.lastname: Rilinger
authors.forename: T
authors.initials: T
authors.lastname: Fleiter
mesh_terms: D000328:Adult; D000368:Aged; D001011:Aorta / Q000378:metabolism; D001027:Aortography; D003287:Contrast Media / Q000008:administration & dosage* / Q000378:metabolism; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media