Pyridoxin-responsive anaemia in a patient with a history of polycythaemia vera.
Pancytopenia in the course of polycythaemia vera (PV) following the proliferative and stable phase, ultimately leads to a spent phase characterized by extensive marrow fibrosis. We describe a patient with a history of PV and pancytopenia caused by myelodysplasia, before a genuine end stage myelofibrosis had occurred. The related anaemia was responsive to pyridoxin.
Van Gameren
I I
II
Department of Internal Medicine, Martini Hospital, van Swietenlaan, The Netherlands.
Wijnja
L
L
Louwes
H
H
de Wolf
J T
JT
D001853:Bone Marrow / Q000187:drug effects / Q000473:pathology; D005260:Female; D005355:Fibrosis; D006801:Humans; D008875:Middle Aged; D010198:Pancytopenia / Q000188:drug therapy* / Q000209:etiology; D011087:Polycythemia Vera / Q000150:complications*; D011736:Pyridoxine / Q000627:therapeutic use*
D011736:Pyridoxine