title: Non-surgical treatment of vestibular schwannoma patients.
abstract: The aim of the study was to evaluate the course of vestibular schwannoma (VS) when surgery was not attempted. The tumor may be slowly growing and surgery a risk for a patient. Twenty-eight patients out of 390 VS patients during years 1981-1995 were primarily recommended a non-surgical treatment. Another 3 patients refused the operation. Altogether 23 women and 8 men were evaluated. Their age varied from 30.6 to 74.6 years (median 56.7 years). Tumor size varied from 5 to 30 mm (median 15.0 mm) at the beginning of the follow-up. Patients symptoms, condition and other illnesses were recorded. Seven patients had neurofibromatosis 2 (3 of them had one hearing ear), 2 had severe mental problems, 5 patients had their only hearing ear and 11 patients were not recommended an operation because of their age and other illnesses. Patients were controlled with MRI at intervals from 1 to 3 years. The follow-up time varied from 1 to 20 years (median 2.0 years). The average tumor growth rate among unilateral VS patients was 0.035 cm/year and among bilateral tumors the average tumor growth rate was 0.015 cm/year. Two patients were later operated on, one 2 years after diagnosis because of the tumor growth and the other one 4 years after diagnosis-she had refused an operation earlier. Two patients could not be reached. Another patient had tumor growth but because of his illnesses he got a radiation beam instead of an operation. The majority of the patients could live fairly normal lives and required no treatment. Surgery is not the only alternative to VS patients. Wait-and-see policy is also a good alternative to those who have high operation risk or who refuse an operation.
authors.affiliation: Department of Otolaryngology, University of Helsinki, Finland.
authors.forename: H
authors.initials: H
authors.lastname: Levo
authors.forename: I
authors.initials: I
authors.lastname: Pyykkö
authors.forename: G
authors.initials: G
authors.lastname: Blomstedt
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D013997:Time Factors; D016312:Treatment Refusal