Central nervous system involvement as a relapse of disseminated histoplasmosis in an Italian AIDS patient.
A case of an Italian AIDS patient who developed both meningitis and cerebral mass lesion as a final relapse of disseminated histoplasmosis is reported. Central nervous system (CNS) involvement occurred while the patient was receiving both amphotericin B and itraconazole as maintenance therapy, thus indicating the difficulty of eradicating histoplasmosis in patients with AIDS.
Vullo
V
V
Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Rome, Italy.
Mastroianni
C M
CM
Ferone
U
U
Trinchieri
V
V
Folgori
F
F
Lichtner
M
M
D'Agostino
C
C
D017088:AIDS-Related Opportunistic Infections / Q000134:cerebrospinal fluid / Q000150:complications* / Q000188:drug therapy; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D017809:Fatal Outcome; D006658:Histoplasma; D006660:Histoplasmosis / Q000134:cerebrospinal fluid / Q000139:chemically induced* / Q000188:drug therapy; D006801:Humans; D007558:Italy; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008581:Meningitis / Q000188:drug therapy / Q000382:microbiology*
D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B