title: [Pulmonary embolism and cerebral stroke from paradoxical embolism in a young woman].
abstract: We describe a case of pulmonary embolism and ischemic stroke due to paradoxical embolism in a healthy young woman taking oral contraceptives to treat an ovarian cyst. It was not possible to identify the site of the thromboembolus. Ultrasound techniques played an important role in identifying the peripheral arterial obstructions and in diagnosing acute pulmonary hypertension. Transesophageal echocardiography provided detailed information on both the morphology and the evolution of the atrial thrombus straddling the foramen ovale within the aneurysmal interatrial septum. The patient was given anticoagulant treatment, initially with heparin and subsequently with warfarin over a period of six months. Repeated ultrasound controls showed no thrombus, regression of the signs of pulmonary hypertension and, lastly unchanged systemic arterial obstruction.
authors.affiliation: Istituto di Cardiologia, Ospedale Silvestrini, Università degli Studi, Perugia.
authors.forename: S
authors.initials: S
authors.lastname: Mandorla
authors.forename: M
authors.initials: M
authors.lastname: Fronticelli
authors.forename: M R
authors.initials: MR
authors.lastname: Taliani
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging / Q000209:etiology*; D003278:Contraceptives, Oral, Hormonal / Q000627:therapeutic use; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D010048:Ovarian Cysts / Q000150:complications / Q000188:drug therapy; D011655:Pulmonary Embolism / Q000000981:diagnostic imaging / Q000209:etiology*; D013923:Thromboembolism / Q000150:complications* / Q000000981:diagnostic imaging; D014463:Ultrasonography; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D003278:Contraceptives, Oral, Hormonal; D014859:Warfarin; D006493:Heparin