title: Erythroxan diterpenes from Fagonia glutinosa.
abstract: Further investigation of the ether extract of the aerial parts of Fagonia glutinosa utilizing the brine shrimp bioassay resulted in the isolation of two new cytotoxic erythroxan diterpenes: 1 alpha, 10 alpha-epoxy-2-oxofagonene (1) and 1 beta, 10 beta-epoxy-2-oxofagonene (2). In addition, two inactive diterpenes, 2-oxofagonene (3) and its previously reported isomer 2-oxo-5-epi-fagonene (4), were also isolated.
authors.forename: M S
authors.initials: MS
authors.lastname: Abdel-Kader
authors.forename: A A
authors.initials: AA
authors.lastname: Omar
authors.forename: F R
authors.initials: FR
authors.lastname: Stermitz
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004224:Diterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D015394:Molecular Structure; D010944:Plants / Q000737:chemistry*; D013057:Spectrum Analysis
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D004224:Diterpenes