Excitatory synaptic transmission in the rat medical vestibular nucleus.
In vitro brainstem slice preparations have provided the opportunity to obtain accurate information about the neuropharmacology of the vestibular system. By stimulating the root of the eighth cranial nerve, excitatory synaptic transmission in the rat medial vestibular nucleus has been observed and analyzed with extra- and intra-cellular recordings. Recently, tight-seal, whole-cell recordings, perforated whole-cell recordings and microfluorometry of Ca2+ were applied to in vitro brainstem slice preparations to obtain detailed information. Excitatory synaptic transmission to MVN neurons is reviewed.
Takahashi
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Y
Department of Otolaryngology, Osaka University Medical School, Japan.
Kubo
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T
D000818:Animals; D001933:Brain Stem / Q000502:physiology; D002118:Calcium / Q000378:metabolism / Q000502:physiology; D015220:Calcium Channels / Q000502:physiology; D003592:Cytophotometry; D005071:Evoked Potentials / Q000187:drug effects / Q000502:physiology; D018691:Excitatory Amino Acid Antagonists / Q000494:pharmacology; D009474:Neurons / Q000502:physiology; D051381:Rats; D017470:Receptors, Glutamate / Q000187:drug effects / Q000502:physiology; D016194:Receptors, N-Methyl-D-Aspartate / Q000187:drug effects / Q000502:physiology; D009435:Synaptic Transmission / Q000187:drug effects / Q000502:physiology*; D014726:Vestibular Nuclei / Q000502:physiology*; D000159:Vestibulocochlear Nerve / Q000502:physiology
D015220:Calcium Channels; D018691:Excitatory Amino Acid Antagonists; D017470:Receptors, Glutamate; D016194:Receptors, N-Methyl-D-Aspartate; D002118:Calcium