title: A cyanobacterial phytochrome two-component light sensory system.
abstract: The biliprotein phytochrome regulates plant growth and developmental responses to the ambient light environment through an unknown mechanism. Biochemical analyses demonstrate that phytochrome is an ancient molecule that evolved from a more compact light sensor in cyanobacteria. The cyanobacterial phytochrome Cph1 is a light-regulated histidine kinase that mediates red, far-red reversible phosphorylation of a small response regulator, Rcp1 (response regulator for cyanobacterial phytochrome), encoded by the adjacent gene, thus implicating protein phosphorylation-dephosphorylation in the initial step of light signal transduction by phytochrome.
authors.affiliation: Section of Molecular and Cellular Biology, University of California, Davis, CA 95616, USA.
authors.forename: K C
authors.initials: KC
authors.lastname: Yeh
authors.forename: S H
authors.initials: SH
authors.lastname: Wu
authors.forename: J T
authors.initials: JT
authors.lastname: Murphy
authors.forename: J C
authors.initials: JC
authors.lastname: Lagarias
mesh_terms: D000595:Amino Acid Sequence; D001426:Bacterial Proteins; D003001:Cloning, Molecular; D000458:Cyanobacteria / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D005798:Genes, Bacterial; D000071677:Histidine Kinase; D008027:Light; D008969:Molecular Sequence Data; D009876:Operon; D010766:Phosphorylation; D011494:Protein Kinases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D011506:Proteins; D011993:Recombinant Fusion Proteins / Q000737:chemistry / Q000378:metabolism; D017384:Sequence Deletion; D015398:Signal Transduction
chemical_list: D001426:Bacterial Proteins; D011506:Proteins; C107945:Rcp1 protein, Synechocystis; D011993:Recombinant Fusion Proteins; D011494:Protein Kinases; D000071677:Histidine Kinase