title: Active-site studies of enzymes by secondary structure prediction and by molecular modeling.
abstract: Since the determination of the tertiary structure by X-ray crystallography has been achieved only for a limited number of proteins, alternative approaches are being sought. In this article, the use of secondary structure prediction and of molecular modeling is discussed. Several examples are analyzed in detail.
authors.affiliation: Laboratorio de Biofísica Molecular, Facultad de Ciencias Biológicas, Universidad de Concepción, Chile.
authors.forename: H
authors.initials: H
authors.lastname: Cid
authors.forename: M
authors.initials: M
authors.lastname: Bunster
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D004789:Enzyme Activation; D008958:Models, Molecular; D008969:Molecular Sequence Data; D017433:Protein Structure, Secondary; D014965:X-Rays