Calcium, magnesium, and zinc status in experimental hyperthyroidism.
In this study, experimental hyperthyroidism was established and used to investigate possible alterations in the calcium (Ca), magnesium (Mg), and zinc (Zn) homeostasis by assessing their concentrations in plasma and erythrocytes. In the L-thyroxine-induced hyperthyroidism condition, the experimental animals show a significant decrease in erythrocyte Ca, Mg, and Zn concentrations, and a significant decrease in plasma Mg concentration. Significant positive correlations were found for Mg and Zn both in plasma and in erythrocytes. The results suggest that the homeostasis of Ca, Mg, and Zn is altered during experimental hyperthyroidism.
Simsek
G
G
Department of Physiology, Faculty of Medicine, University of Istanbul, Cerrahpasa, Turkey.
Andican
G
G
Unal
E
E
Hatemi
H
H
Yigit
G
G
Candan
G
G
D000818:Animals; D002118:Calcium / Q000097:blood*; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D006980:Hyperthyroidism / Q000097:blood*; D008274:Magnesium / Q000097:blood*; D051381:Rats; D017208:Rats, Wistar; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D015032:Zinc / Q000097:blood*
D013972:Thyrotropin; D008274:Magnesium; D015032:Zinc; D013974:Thyroxine; D002118:Calcium