title: Solitary extramedullary plasmacytoma.
abstract: A rare case of abdominal plasmacytoma is described. A computed guided biopsy of abdominal mass permitted an accurate diagnosis. Blood findings revealed an increased gamma-globulin level and serum immunoelectrophoresis revealed high IgG-kappa spike. Bone marrow biopsy resulted negative for neoplastic infiltration. Plasmacytoma is a malignant proliferation of differentiated B lymphocytes which produce immunoglobulin. In our case, microscopically, biopsy of abdominal mass revealed the presence of plasmablasts with bizarre multiforme nuclei, spindled contours and positive immunoenzymatic reaction for CD38, suggestive for plasma cell proliferation.
authors.affiliation: Dipartimento di Medicina Interna e Nefrologia, Università di Pavia, IRCCS Policlinico San Matteo.
authors.forename: A
authors.initials: A
authors.lastname: Mazzone
authors.forename: S
authors.initials: S
authors.lastname: Girola
authors.forename: I
authors.initials: I
authors.lastname: Mazzucchelli
authors.forename: E M
authors.initials: EM
authors.lastname: Di Maggio
authors.forename: C
authors.initials: C
authors.lastname: Cusa
authors.forename: M
authors.initials: M
authors.lastname: Celano
mesh_terms: D000008:Abdominal Neoplasms / Q000175:diagnosis / Q000473:pathology; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D005260:Female; D006801:Humans; D010954:Plasmacytoma / Q000175:diagnosis / Q000473:pathology; D014057:Tomography, X-Ray Computed