[IL-6 gene expression in human tumor cell lines].
Using Northern blot techniques and IL-6-dependent cell line proliferating response method, the IL-6 gene expression in 8 sorts of human tumor cell lines and the IL-6 biologic activity in 5 sorts of medium were investigated. The results revealed that IL-6mRNA was positively expressed in 7 sorts of these cell lines and there were differential IL-6 biologic activity in 5 sorts of assayed medium. These results may providea basis for further research.
Zhong
H
H
Institute of Urology, Beijing Medical University.
Gu
F
F
Yu
L
L
D015152:Blotting, Northern; D001943:Breast Neoplasms / Q000235:genetics*; D015179:Colorectal Neoplasms / Q000235:genetics*; D015870:Gene Expression; D006801:Humans; D015850:Interleukin-6 / Q000235:genetics* / Q000378:metabolism; D014407:Tumor Cells, Cultured / Q000378:metabolism; D001749:Urinary Bladder Neoplasms / Q000235:genetics*
D015850:Interleukin-6