title: [Chronic inflammation of mucous membranes: integration of immunity and regeneration].
abstract: Lymphoid tissue of mucous membranes is a morphological basis for local immunity. Lymphocytes of mucous membranes are bifunctional: reception of antigenic information and regulation of epithelial cells regeneration. The following structural manifestations of intercellular interactions are discussed: expression of HLA-DR antigens by the epithelium and endotheliocytes transforming them into "facultative" antigen-presenting cells; polyclonal plasmocyte proliferation; the exchange of their prevailing IgA phenotype for IgG; cytotoxic and cytogenetic effect of the interepithelial lymphocytes.
authors.forename: A S
authors.initials: AS
authors.lastname: Zinov'ev
authors.forename: A V
authors.initials: AV
authors.lastname: Kononov
mesh_terms: D001980:Bronchi / Q000473:pathology; D002908:Chronic Disease; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D018928:Immunity, Mucosal; D007136:Immunoglobulins / Q000276:immunology; D007249:Inflammation / Q000276:immunology* / Q000473:pathology / Q000503:physiopathology; D007413:Intestinal Mucosa / Q000473:pathology; D012038:Regeneration / Q000502:physiology*
chemical_list: D007136:Immunoglobulins