Digitalization of the mother in treating hydrops fetalis in monochorionic twin with Ebstein's anomaly. Case report.
Hydrops fetalis thought to be due to Ebstein's anomaly was seen at 22 weeks' gestation in one of two fetuses with a monochorionic placenta. Hydrops was treated with maternal digitalization and resolved by the 28th week of gestation. Hydrops did not recur while maternal digitalization continued. A clinical diagnosis of twin-to-twin transfusion syndrome required termination of the pregnancy at 33 weeks of gestation. The twin with Ebstein's anomaly died 22 hours after birth. The other twin survived and was normal at 19 months of age. Thus, administration of digitalis to the mother controlled hydrops fetalis in one fetus, and ultimately led to the survival of the healthy infant.
Koike
T
T
Department of Obstetrics and Gynecology, Jichi Medical School, Tochigi, Japan.
Minakami
H
H
Shiraishi
H
H
Ogawa
S
S
Matsubara
S
S
Honma
Y
Y
Sato
I
I
D000328:Adult; D000653:Amniotic Fluid / Q000737:chemistry; D004077:Digoxin / Q000032:analysis / Q000097:blood / Q000627:therapeutic use*; D004200:Diseases in Twins; D004437:Ebstein Anomaly / Q000150:complications*; D005260:Female; D005313:Fetal Death / Q000517:prevention & control; D006801:Humans; D015160:Hydrops Fetalis / Q000188:drug therapy* / Q000209:etiology*; D011247:Pregnancy
D004077:Digoxin