title: Pregnancy in infertile PCOD patients. Complications and outcome.
abstract: OBJECTIVE
  To evaluate the complications and outcome of pregnancy in women with polycystic ovary disease (PCOD).
  
  
  METHODS
  The course and outcome of 47 singleton pregnancies in women with well-documented PCOD were compared with those in 100 healthy controls.
  
  
  RESULTS
  Women with PCOD had a significantly higher body mass index as compared to the control group (P < .05); however, the proportion of lean versus obese subjects in the two groups was similar. The incidence of an abnormal glucose challenge test, gestational diabetes mellitus and pregnancy-induced hypertension was significantly increased in pregnant women with PCOD (P < .05). When lean PCOD subjects were compared with lean control subjects, the difference in the incidence of the above complications was still significant (P < .05). The incidence of pregnancy complications was similar when obese PCOD subjects were compared with obese controls.
  
  
  CONCLUSIONS
  Women with PCOD were at increased risk of gestational diabetes and pregnancy-induced hypertension, and this risk appeared to be independent of body mass index.
authors.affiliation: Department of Obstetrics and Gynecology, University of Hacettepe, Faculty of Medicine, Ankara, Turkey.
authors.forename: B
authors.initials: B
authors.lastname: Urman
authors.forename: E
authors.initials: E
authors.lastname: Sarac
authors.forename: L
authors.initials: L
authors.lastname: Dogan
authors.forename: T
authors.initials: T
authors.lastname: Gurgan
mesh_terms: D000328:Adult; D015992:Body Mass Index; D002996:Clomiphene / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D016640:Diabetes, Gestational / Q000209:etiology; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D005951:Glucose Tolerance Test; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007247:Infertility, Female / Q000209:etiology* / Q000628:therapy; D008596:Menotropins / Q000627:therapeutic use; D010062:Ovulation Induction; D011085:Polycystic Ovary Syndrome / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome
chemical_list: D002996:Clomiphene; D008596:Menotropins; D003907:Dexamethasone