title: [A case of solitary metastatic splenic tumor of ovarian carcinoma].
abstract: The case was a 67-year-old female. In March, 1993, bilateral oophrectomy + total hysterectomy+omentectomy were done, for stage III ovarian cancer with peritoneal dissemination, and high CA 125 level (2100 U/ml). As postoperative chemotherapy, intraperitoneal injection of CDDP 150 mg (4 courses), and intravenous injection of CAP (CPA 500 mg/ m2 + epirubicin 25 mg/m2 + CDDP 50 mg/m2) (10 courses) were undertaken. In March, 1995, in abdominal CT scan, a solitary splenic tumor was found and the tumor marker (CA 125) was again elevated, and splenic metastasis was suspected. In June, 1995, intravenous injection of CDDP 70 mg/m2 + CPT-11 60 mg/m2 (1 course) was given, and the splenic tumor enlarged gradually. In February, 1996, a splenectomy was done. In pathological findings, the tumor proved to be poorly-differentiated adenocarcinoma the same as primary ovarian cancer, and after splenectomy, CA 125 fell below the normal value. The diagnosis was solitary splenic metastasis from ovarian carcinoma.
authors.affiliation: Dept. of Surgery, Tohkoh-Kai Social Group Chofu Hospital.
authors.forename: A
authors.initials: A
authors.lastname: Kobayashi
authors.forename: M
authors.initials: M
authors.lastname: Yamaguchi
authors.forename: N
authors.initials: N
authors.lastname: Koarai
authors.forename: N
authors.initials: N
authors.lastname: Sugizaki
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary* / Q000601:surgery; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D004334:Drug Administration Schedule; D015251:Epirubicin / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007044:Hysterectomy; D000077146:Irinotecan; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000556:secondary* / Q000601:surgery
chemical_list: D015251:Epirubicin; D000077146:Irinotecan; D003520:Cyclophosphamide; D002945:Cisplatin; D002166:Camptothecin