Focal myasthenia gravis in a dog.
A 10-month-old American cocker spaniel was evaluated for megaesophagus, aspiration pneumonia, but no appendicular muscle weakness. During hospitalization, weakness of the facial muscles developed, this resolved with anticholinesterase administration. Serum antibodies against acetylcholine receptors were documented, confirming the diagnosis of focal myasthenia gravis. Diagnosis, management, and medical treatment are discussed.
Webb
A A
AA
Department of Veterinary Internal Medicine, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon.
Taylor
S M
SM
McPhee
L
L
D000818:Animals; D001323:Autoantibodies / Q000097:blood / Q000276:immunology; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D004285:Dogs; D004931:Esophageal Achalasia / Q000175:diagnosis / Q000662:veterinary; D007037:Hypothyroidism / Q000175:diagnosis / Q000662:veterinary; D008297:Male; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D009388:Neostigmine / Q000627:therapeutic use; D011950:Receptors, Cholinergic / Q000276:immunology
D001323:Autoantibodies; D002800:Cholinesterase Inhibitors; D011950:Receptors, Cholinergic; D009388:Neostigmine