title: Residual stresses in the human aorta and their influences by growth and remodelling.
abstract: The aim of the present work is to demonstrate of the influence of the adventitia on distribution of residual stresses in the human aorta. The biomaterial increase in media as well as in adventitia in the course of the aorta's growth is formed by an intussusceptive mechanism of growth. In children's aortas, formative elastin lamellae are wavy with high amplitude perpendicular to the aortic surface. In adults' aortas the waves become smoother (stepwise) towards the adventitia. Also introduced is the growth function, which characterizes the biomaterial growth and the interference between the media and adventitial layers. It is possible to expect an extraordinary variability in the formation of the aortic wall tissue in the course of its growth as a result of metabolic and humoral influences and magnitude of the residual stresses in the course of growth.
authors.affiliation: Department of Biomechanics and Strength of Materials, Czech Technical University, Faculty of Mechanical Engineering, Prague, Czech Republic.
authors.forename: J
authors.initials: J
authors.lastname: Valenta
authors.forename: T
authors.initials: T
authors.lastname: Hrus
authors.forename: M
authors.initials: M
authors.lastname: Sochor
authors.forename: R
authors.initials: R
authors.lastname: Cihák
authors.forename: C
authors.initials: C
authors.lastname: Povýsil
authors.forename: J
authors.initials: J
authors.lastname: Steidl
mesh_terms: D000328:Adult; D000368:Aged; D001011:Aorta / Q000166:cytology / Q000502:physiology*; D001013:Aorta, Thoracic / Q000166:cytology / Q000502:physiology*; D003331:Coronary Vessels / Q000502:physiology; D004548:Elasticity; D004549:Elastin / Q000032:analysis / Q000502:physiology; D004730:Endothelium, Vascular / Q000166:cytology; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D008955:Models, Cardiovascular; D013314:Stress, Mechanical
chemical_list: D004549:Elastin