Interrelationship between tumour virus receptors, A and C, coded by host cell genes in fowl.
Bryan Standard strain of Rous Sarcoma Virus (BS-RSV) of subgroup A and pseudotype of Bryan high titre RSV(RAV-49) of subgroup C and an equal mixture of subgroup A and subgroup C virus were inoculated to 11-day old embryos of white leghorn (WL), Australorp (AL) and f1 and f2 generations of crosses between WL and AL breeds of fowl to detect and estimate the interrelationship between tumour virus receptor coding host cell genes of tva and tvc loci. Linkage values estimated on a pooled sex basis were 0.08 +/- 0.03 and 0.10 +/- 0.03 for WL and AL breeds respectively and 0.09 on pooled breed basis. This clearly indicates that the tva and tvc loci are indeed closely linked in WL and AL breeds of fowl and supports the concept of using subgroup C virus to raise stocks resistant to subgroup A virus infection.
Mehta
S C
SC
PL-480 Project, Indian Veterinary Research Institute, Izatnagar, India.
Pani
P K
PK
D000818:Animals; D001358:Avian Sarcoma Viruses / Q000378:metabolism; D002642:Chick Embryo; D002645:Chickens / Q000235:genetics*; D004198:Disease Susceptibility; D008040:Genetic Linkage; D011991:Receptors, Virus / Q000235:genetics / Q000378:metabolism*; D013045:Species Specificity
D011991:Receptors, Virus