[Thromboembolism prophylaxis in pregnancy and labor].
Oral anticoagulants are contraindicated during pregnancy, especially during the I and III trimester, therefore heparin is recommended instead. We used fraxiparine s.c. once daily in prophylactic doses in 6 patients during pregnancy and labor (mean time of prophylaxis 6.5 months). Two of them received fraxiparine because of mechanical valve prosthesis, four after deep venous thrombosis occurring during the first few weeks of pregnancy. The pregnancies were uneventful, thromboembolic or haemorrhagic complications during delivery did not occur. Newborns were healthy, disturbances of hemostasis were not observed.
Czestochowska
E
E
IV Kliniki Chorób Wewnetrznych, Instytutu Chorób Wewnetrznych Akademii Medycznej w Gdańsku.
D000925:Anticoagulants / Q000627:therapeutic use*; D004334:Drug Administration Schedule; D005260:Female; D006350:Heart Valve Prosthesis; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D017762:Nadroparin / Q000627:therapeutic use*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000097:blood / Q000517:prevention & control*; D011256:Pregnancy Outcome; D013923:Thromboembolism / Q000097:blood / Q000517:prevention & control*; D013924:Thrombophlebitis / Q000097:blood / Q000517:prevention & control*
D000925:Anticoagulants; D017762:Nadroparin