The hypoglycemic effect of chloroquine.
Ten persons were studied to observe the effect of intravenous administration of chloroquine on serum glucose level. Ten healthy individuals were given 800 mg of chloroquine in three hours infusion. There was a significant (p = 0.001) fall of 25.86 per cent of initial blood glucose level in test group, while it was only 10.47 per cent in control group. Therefore, it is emphasized that seriously III patients and those who are prore to hypoglycemia should be carefully monitored when giving IV chlorquine.
Goyal
V
V
Department of Medicine, R.N.T. Medical College Udaipur.
Bordia
A
A
D000328:Adult; D000962:Antimalarials / Q000008:administration & dosage / Q000494:pharmacology*; D001786:Blood Glucose / Q000032:analysis / Q000187:drug effects; D002738:Chloroquine / Q000008:administration & dosage / Q000494:pharmacology*; D003243:Consciousness / Q000187:drug effects; D004311:Double-Blind Method; D005260:Female; D006261:Headache / Q000139:chemically induced; D006801:Humans; D007003:Hypoglycemia / Q000097:blood / Q000503:physiopathology; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000494:pharmacology*; D007262:Infusions, Intravenous; D008297:Male
D000962:Antimalarials; D001786:Blood Glucose; D007004:Hypoglycemic Agents; D002738:Chloroquine