title: Double minute chromosomes and myelodysplastic syndrome: a case report and literature review.
abstract: Double minute chromosomes (dmin) occur in about 3.3-10.6% of acute leukemia, especially in the elderly. However, dmins are relatively rare in myelodysplastic syndrome (MDS). We describe a case of refractory anemia with excess blasts associated with complex cytogenetic abnormalities, dmins, and brief survival.
authors.affiliation: Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock 79430, USA.
authors.forename: Y K
authors.initials: YK
authors.lastname: Keung
authors.forename: E
authors.initials: E
authors.lastname: Cobos
authors.forename: D
authors.initials: D
authors.lastname: Morgan
authors.forename: R P
authors.initials: RP
authors.lastname: Whitehead
authors.forename: V
authors.initials: V
authors.lastname: Tonk
mesh_terms: D000368:Aged; D002869:Chromosome Aberrations / Q000235:genetics* / Q000473:pathology; D002871:Chromosome Banding; D025063:Chromosome Disorders; D005260:Female; D005784:Gene Amplification; D006801:Humans; D008297:Male; D008875:Middle Aged; D009190:Myelodysplastic Syndromes / Q000235:genetics* / Q000473:pathology