Posttransplantation lymphoproliferative disorder in a renal allograft recipient.
As a complication of immunosuppressive therapy, solid organ and bone marrow transplant recipients have an increased risk of developing post transplant lymphoproliferative disorder (PTLD). Epstein-Barr virus (EBV) infection and the degree of immunosuppression have been identified as risk factors for the development of this complication. The clinical presentation includes a spectrum of disorders ranging from a benign infectious mononucleosis-like syndrome with fever and cervical adenopathy to multiorgan failure leading to death. Although, T-cell lesions have been described, PTLD is usually associated with a polyclonal or monoclonal B-cell proliferation. In this report, we present a renal transplant recipient with a perirenal mass diagnosed as PTLD.
Goral
S
S
Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232-2372, USA. goral.simin@nashville.va.gov
Felgar
R
R
Shappell
S
S
D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D007668:Kidney / Q000000981:diagnostic imaging / Q000473:pathology*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008232:Lymphoproliferative Disorders / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D011859:Radiography