title: Studies of apolipoprotein B-100 metabolism using radiotracers and stable isotopes.
abstract: Apolipoprotein B metabolism can be investigated in-vivo either by exogenous radiolabeling of preformed lipoproteins or by endogenous labelling of denovo synthesized apo B using a stable isotope substituted amino acid tracer. The potential of both methods and results obtained by in-vivo studies in genetically determined dys- or hyperlipidaemic subjects will be discussed.
authors.affiliation: Institut für Klinische Chemie, Klinikum Grosshadern, München, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Demant
authors.forename: C J
authors.initials: CJ
authors.lastname: Packard
mesh_terms: D053299:Apolipoprotein B-100; D001055:Apolipoproteins B / Q000378:metabolism*; D003903:Deuterium; D006801:Humans; D006949:Hyperlipidemias / Q000378:metabolism*; D007457:Iodine Radioisotopes; D007553:Isotope Labeling / Q000379:methods*; D008074:Lipoproteins / Q000378:metabolism*
chemical_list: D053299:Apolipoprotein B-100; D001055:Apolipoproteins B; D007457:Iodine Radioisotopes; D008074:Lipoproteins; D003903:Deuterium