Adrenal carcinosarcoma--a case report.
Carcinosarcoma of the adrenal gland is an extremely rare variant of adrenocortical carcinoma, characterized by a biphasic pattern of carcinoma and sarcoma-like components. We report a case of adrenal carcinosarcoma occurring in a 61-year-old Korean man who presented with right flank pain of one month duration radiating to the back and right iliac crest. The tumor measured 12 x 12 x 7 cm and adhered to the liver and right upper pole of the kidney. The carcinomatous component of the tumor showed polygonal cells in a broad anastomosing trabecular pattern with delicate slit-like vascular channels; the sarcomatous component showed uniform spindled cells in a fascicular pattern. Both the carcinomatous and sarcomatous portions of the tumor were positive for pan-cytokeratin, and vimentin stained only the sarcomatous areas.
Lee
M S
MS
Department of Pathology and Urology, Seoul National University College of Medicine, Korea.
Park
I A
IA
Chi
J G
JG
Ham
E K
EK
Lee
K C
KC
Lee
C W
CW
D000310:Adrenal Gland Neoplasms / Q000175:diagnosis*; D002296:Carcinosarcoma / Q000175:diagnosis*; D006801:Humans; D007723:Korea; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed