Selection of prognostic factors of acute hepatitis type non-A, non-B for patient listing for liver transplantation.
The aim of this study was to select prognostic factors from information available on admission in order to list patients for liver transplantation before the onset of hepatic encephalopathy in patients with fatal hepatitis type non-A, non-B. Information regarding patient profile and biochemical data obtained on admission was analyzed by multiple stepwise logistic regression, and independent prognostic factors related to death were selected. Four parameters were selected as independent prognostic factors. Patient age (over 50 years), serum total bilirubin level (over 10 mg/dl), peripheral leukocyte count, and prothrombin time were independently related to death. Positive predictive value, negative predictive value, and predictive accuracy were 0.86, 0.79, and 0.84, respectively. Our model is able to predict a patient's fatal outcome much earlier than other currently used models. It will be helpful for early referral to a transplant center.
Kumashiro
R
R
Second Department of Medicine, Kurume University School of Medicine, Fukuoka, Japan.
Sata
M
M
Koga
Y
Y
Suzuki
H
H
Noguchi
K
K
Ishii
K
K
Kusaba
N
N
Tanikawa
K
K
D000328:Adult; D000368:Aged; D006525:Hepatitis, Viral, Human / Q000401:mortality* / Q000601:surgery; D006801:Humans; D016031:Liver Transplantation / Q000706:statistics & numerical data; D008875:Middle Aged; D011379:Prognosis; D015996:Survival Rate; D009927:Tissue and Organ Procurement / Q000379:methods*; D014850:Waiting Lists