[Changes in the sensitivity of Escherichia coli to 6 antimicrobial agents during the last 12 years. Group of Microbiologists of County Hospitals of Catalonia].
OBJECTIVE
To study the current state and development in the sensitivity of Escherichia coli during 12 years, in order to find the use of 6 antimicrobials.


METHODS
A descriptive study of the annual sensitivity percentages of E. coli strains isolated from clinical samples between 1984 and 1995.


METHODS
Microbiology Laboratories in 15 County Hospitals in the province of Barcelona.


METHODS
E. coli strains, isolated from clinically significant samples, were studied for sensitivity against antimicrobials.


RESULTS
Cefuroxime and Gentamicin had in vitro sensibility above 94%. Current sensitivity of E. coli to Norfloxacin was 85%. Amoxicillin-Clavulanic acid maintained its sensitivity at about 80% with few variations. Ampicillin and Co-trimoxazole had steady sensitivity figures, always below 50 and 70%, respectively.


CONCLUSIONS
Progressive decrease in the sensitivity of E. coli strains to Norfloxacin was observed. There was excellent sensitivity to Cefuroxime and Gentamicin.
Sauca
G
G
Consorci Sanitari Mataró, Hospital Sant Jaume de Calella, Barcelona.
Gallés
C
C
Gasós
M A
MA
D000658:Amoxicillin / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002444:Cefuroxime / Q000494:pharmacology; D002511:Cephalosporins / Q000494:pharmacology; D019818:Clavulanic Acid; D002969:Clavulanic Acids / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects* / Q000302:isolation & purification; D005839:Gentamicins / Q000494:pharmacology; D006801:Humans; D008826:Microbial Sensitivity Tests; D009643:Norfloxacin / Q000494:pharmacology; D010406:Penicillins / Q000494:pharmacology; D013030:Spain; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D002969:Clavulanic Acids; D005839:Gentamicins; D010406:Penicillins; D019818:Clavulanic Acid; D000658:Amoxicillin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D009643:Norfloxacin; D002444:Cefuroxime