Isolated venlafaxine-induced serotonin syndrome.
Serotonin syndrome is a potentially fatal complication of serotonergic drug therapy. Usually, serotonin syndrome occurs with the concomitant use of two serotonergic drugs; this case report describes a patient with a classic presentation of serotonin syndrome induced solely by a venlafaxine overdose. Emergency physicians need to be aware that the serotonin syndrome may occur not only with serotonergic drug combinations but also with overdoses of a single potent serotonergic agent such as venlafaxine.
Kolecki
P
P
Department of Medical Toxicology, Good Samaritan Regional Medical Center, Phoenix, Arizona 85006, USA.
D000328:Adult; D001342:Autonomic Nervous System Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D003511:Cyclohexanols / Q000506:poisoning*; D062787:Drug Overdose; D006801:Humans; D008297:Male; D009468:Neuromuscular Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D017367:Selective Serotonin Reuptake Inhibitors / Q000506:poisoning*; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D013577:Syndrome; D000069470:Venlafaxine Hydrochloride
D003511:Cyclohexanols; D017367:Selective Serotonin Reuptake Inhibitors; D000069470:Venlafaxine Hydrochloride