Prognostic indicators in medical rehabilitation of traumatic brain injury: a commentary and review.
The National Information System (NIS) project is developing consensus opinion regarding a proposed structural framework for the prognostic data to be collected as part of this proposed multicenter research effort on severe traumatic brain injury (TBI). This article provide a brief history of the process, examines challenges facing rehabilitation research in this particular area, discusses reasons for identifying prognostic data within the research context of the NIS project, and describes methodologies for use of mathematical models in predicting outcome from TBI. The literature regarding prognostic parameters in severe TBI is briefly reviewed, utilizing three broad parameter categorizations: preinjury, injury, and postinjury. The implications of this research and directions for further study within the NIS project are discussed.
Zasler
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National NeuroRehabilitation Consortium, Inc., Glen Allen, VA 23060, USA.
D001930:Brain Injuries / Q000503:physiopathology / Q000534:rehabilitation*; D004594:Electrophysiology; D006305:Health Status Indicators; D006801:Humans; D017063:Outcome Assessment, Health Care; D011237:Predictive Value of Tests; D011379:Prognosis