title: [The effect of the serotonin level on the postsynaptically induced potentiation of neuronal responses in the snail].
abstract: The EPSP potentiation induced by the intracellular tetanization of a postsynaptic neuron was studied in the identified neurons of a terrestrial Helix lucorum snail. The high-frequency intracellular tetanization of the command neuron induced a two-phase long-term increase in the amplitude of synaptic responses. The role of 5-HT was studied in potentiation formation. The obtained evidence suggests that the presence of a certain 5-HT concentration in the extracellular fluid is necessary for the second phase formation while the first (short-term) phase is insensible to the 5-HT level in the CNS.
authors.forename: A Iu
authors.initials: AIu
authors.lastname: Malyshev
authors.forename: N I
authors.initials: NI
authors.lastname: Bravarenko
authors.forename: A S
authors.initials: AS
authors.lastname: Pivovarov
authors.forename: P M
authors.initials: PM
authors.lastname: Balaban
mesh_terms: D015116:5,7-Dihydroxytryptamine / Q000494:pharmacology; D000109:Acetylcholine / Q000494:pharmacology; D000818:Animals; D004558:Electric Stimulation / Q000379:methods; D006372:Helix, Snails / Q000187:drug effects / Q000502:physiology*; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D008839:Microelectrodes; D009474:Neurons / Q000187:drug effects / Q000502:physiology*; D009498:Neurotoxins / Q000494:pharmacology; D017981:Receptors, Neurotransmitter / Q000187:drug effects / Q000502:physiology*; D012701:Serotonin / Q000502:physiology*; D017366:Serotonin Receptor Agonists / Q000494:pharmacology; D013997:Time Factors
chemical_list: D009498:Neurotoxins; D017981:Receptors, Neurotransmitter; D017366:Serotonin Receptor Agonists; D015116:5,7-Dihydroxytryptamine; D012701:Serotonin; D000109:Acetylcholine