title: IgG concentration in mammary secretions of goats throughout lactation in healthy and coagulase-negative staphylococci infected udders.
abstract: Radial immunodiffusion was used to determine immunoglobulin (Ig)-G concentrations in 16 mammary secretions from uninfected udder halves and in 10-14 secretions from halves subclinically infected with coagulase-negative staphylococci in goats throughout lactation. IgG concentrations in samples from uninfected halves decreased rapidly during the first week after parturition (P < 0.001 ), henceforth falling slowly up to 30 d post-partum (P < 0.001). From 30 d post-partum to 180 d of lactation, IgG concentration showed a continuous decline to the end of the experiment but these changes were not statistically significant until 150 d after kidding (P < 0.01). IgG concentrations in lacteal secretions of halves harbouring coagulase-negative staphylococci showed a similar pattern, from the first month of lactation, to that observed in healthy udder halves, but concentrations were always lower. These differences were significant from 2 months after parturition (P < 0.001). IgG concentrations were compared with somatic cell counts obtained using an automatic counter (Fossomatic).
authors.affiliation: Departamento de Patología Animal, Facultad Veterinaria de Las Palmas de G.C., Gran Canaria, Spain.
authors.forename: O
authors.initials: O
authors.lastname: Ferrer
authors.forename: F
authors.initials: F
authors.lastname: Real
authors.forename: J M
authors.initials: JM
authors.lastname: Molina
authors.forename: B
authors.initials: B
authors.lastname: Acosta
authors.forename: M C
authors.initials: MC
authors.lastname: Munoz
authors.forename: L
authors.initials: L
authors.lastname: Leon
mesh_terms: D000818:Animals; D002452:Cell Count; D003030:Coagulase / Q000378:metabolism; D003126:Colostrum / Q000166:cytology / Q000276:immunology / Q000382:microbiology; D005260:Female; D015511:Goat Diseases / Q000276:immunology* / Q000382:microbiology / Q000473:pathology; D006041:Goats / Q000276:immunology*; D007074:Immunoglobulin G / Q000378:metabolism*; D007774:Lactation / Q000276:immunology*; D008413:Mastitis / Q000276:immunology* / Q000382:microbiology / Q000473:pathology; D008892:Milk / Q000166:cytology / Q000276:immunology* / Q000382:microbiology; D013203:Staphylococcal Infections / Q000276:immunology / Q000382:microbiology / Q000662:veterinary*; D013210:Staphylococcus / Q000201:enzymology / Q000302:isolation & purification; D013997:Time Factors
chemical_list: D003030:Coagulase; D007074:Immunoglobulin G