title: Serum butyrylcholinesterase (CHE1) polymorphism in a Chilean population of mixed ancestry.
abstract: We estimated the allele frequencies of three variants of serum butyryl-cholinesterase, CHE1*U, CHE1*A and CHE1*F in an urban population of Santiago, Chile, resulting from a mixture of Amerindians with Europeans (mostly Spanish). The CHE1*A frequency was approximately that expected for this population but the incidence of CHE1*F was higher than previous studies would have predicted, probably because in this case more precise techniques were used for its detection. The finding of a CHE1 AK individual suggests that allele CHE1*K is also present at an appreciable frequency in this population.
authors.affiliation: Department of Cellular Biology and Genetics, School of Medicine, University of Chile, Santiago, Chile.
authors.forename: M
authors.initials: M
authors.lastname: Acuña
authors.forename: L
authors.initials: L
authors.lastname: Eaton
mesh_terms: D000483:Alleles; D002091:Butyrylcholinesterase / Q000097:blood / Q000235:genetics*; D002677:Chile; D005060:Europe / Q000208:ethnology; D005260:Female; D005787:Gene Frequency; D006579:Heterozygote; D006720:Homozygote; D006801:Humans; D007199:Indians, South American / Q000235:genetics*; D008297:Male; D010641:Phenotype; D011110:Polymorphism, Genetic; D014505:Urban Population; D044465:White People / Q000235:genetics*
chemical_list: D002091:Butyrylcholinesterase