Collaborative study on evaluation of immunodiagnostic assays in schistosomiasis japonica by treatment efficacy assessment. Collaboration Group.
OBJECTIVE
This paper is the summary of "National Symposium on the Value of Immunodiagnostic Assays in Schistosomiasis by Treatment Effects Assessment" which was directed by the Expert Advisory Committee for Schistosomiasis of the Ministry of Public Health. This symposium was held to evaluate the diagnostic effects of the new system of detection in the sensitivity and specificity by treatment assessment.


METHODS
Twelve laboratories with 14 assay systems participated in this collaborative study, in which, 450 sera were detected by double blind trial using a classical antibody detection with ELISA as a control.


RESULTS
The results showed that 6 test systems were superior or close to the classical antibody detection, especially in evaluating the value of treatment effects.


CONCLUSIONS
It is unanimously recognized that much progress has been made in the research of immunodiagnosis of schistosomiasis in China, but many problems remain to be solved and worth further studying.
Guan
X
X
Department of Parasitology, Nanjing Medical University.
Shi
Y
Y
D000818:Animals; D000947:Antigens, Helminth / Q000097:blood*; D004311:Double-Blind Method; D006801:Humans; D007159:Immunologic Tests; D011223:Praziquantel / Q000627:therapeutic use*; D012549:Schistosoma japonicum / Q000276:immunology*; D012554:Schistosomiasis japonica / Q000175:diagnosis / Q000188:drug therapy*; D012556:Schistosomicides / Q000627:therapeutic use*; D012680:Sensitivity and Specificity
D000947:Antigens, Helminth; D012556:Schistosomicides; D011223:Praziquantel