title: Dramatic response of postthymomectomy myasthenia gravis with multiple lung nodules to corticosteroids.
abstract: A 36-year-old woman underwent thymomectomy and left pneumonectomy with total pleurectomy for stage IVa invasive thymoma without myasthenia gravis. Six years later, a crisis of myasthenia gravis developed associated with multiple lung nodules. Steroid therapy induced remarkable regression of the lung nodules that has persisted for more than 11 months. Concurrently, the clinical severity of her myasthenia gravis markedly decreased and recovered to the extent of permitting her to return to normal life.
authors.affiliation: Department of Thoracic Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kodama
authors.forename: O
authors.initials: O
authors.lastname: Doi
authors.forename: M
authors.initials: M
authors.lastname: Higashiyama
authors.forename: H
authors.initials: H
authors.lastname: Yokouchi
authors.forename: T
authors.initials: T
authors.lastname: Yasuda
authors.forename: H
authors.initials: H
authors.lastname: Funai
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003907:Dexamethasone / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary*; D008775:Methylprednisolone / Q000008:administration & dosage; D009157:Myasthenia Gravis / Q000188:drug therapy / Q000209:etiology*; D009388:Neostigmine / Q000008:administration & dosage; D011241:Prednisone / Q000008:administration & dosage; D011859:Radiography; D013934:Thymectomy; D013945:Thymoma / Q000150:complications / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery; D013953:Thymus Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery
chemical_list: D005938:Glucocorticoids; D009388:Neostigmine; D003907:Dexamethasone; D011241:Prednisone; D008775:Methylprednisolone