Killing two birds with one stone: a chemically plausible scheme for linked nucleic acid replication and coded peptide synthesis.
To understand how life began, we must explain the origins of nucleic acid replication and genetically coded peptide synthesis. Neither of these is easy to explain individually; here, we propose a chemically plausible scheme for the evolution of a process that simultaneously produced both polymers. Later, two separate machineries could have evolved from the linked process.
Sutherland
J D
JD
Dyson Perrins Laboratory, Oxford, UK. john.sutherland@dpl.ox.ac.uk
Blackburn
J M
JM
D004261:DNA Replication; D019143:Evolution, Molecular; D012313:RNA / Q000096:biosynthesis*
D012313:RNA