title: Central nervous system involvement as a relapse of disseminated histoplasmosis in an Italian AIDS patient.
abstract: A case of an Italian AIDS patient who developed both meningitis and cerebral mass lesion as a final relapse of disseminated histoplasmosis is reported. Central nervous system (CNS) involvement occurred while the patient was receiving both amphotericin B and itraconazole as maintenance therapy, thus indicating the difficulty of eradicating histoplasmosis in patients with AIDS.
authors.affiliation: Department of Infectious and Tropical Diseases, La Sapienza University, Policlinico Umberto I, Rome, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Vullo
authors.forename: C M
authors.initials: CM
authors.lastname: Mastroianni
authors.forename: U
authors.initials: U
authors.lastname: Ferone
authors.forename: V
authors.initials: V
authors.lastname: Trinchieri
authors.forename: F
authors.initials: F
authors.lastname: Folgori
authors.forename: M
authors.initials: M
authors.lastname: Lichtner
authors.forename: C
authors.initials: C
authors.lastname: D'Agostino
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000134:cerebrospinal fluid / Q000150:complications* / Q000188:drug therapy; D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D017809:Fatal Outcome; D006658:Histoplasma; D006660:Histoplasmosis / Q000134:cerebrospinal fluid / Q000139:chemically induced* / Q000188:drug therapy; D006801:Humans; D007558:Italy; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008581:Meningitis / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B