New developments in postmenopausal hormone replacement therapy.
In this review we summarize background data that have steadily accumulated to help explain the beneficial actions of oestrogen replacement treatment on cardiovascular disease. The range of beneficial actions on the cardiovascular system is extraordinary, and goes far beyond the widely acknowledged effects on lipoprotein action. We also review recent reports on the beneficial actions of oestrogen treatment on Alzheimer's disease and colorectal cancer. The emphasis throughout is on understanding the mechanisms of benefit.
Prelevic
G M
GM
Department of Medicine, University College of London Medical School, Middlesex Hospital, UK.
Jacobs
H S
HS
D000544:Alzheimer Disease / Q000453:epidemiology / Q000517:prevention & control; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000378:metabolism / Q000517:prevention & control; D003110:Colonic Neoplasms / Q000453:epidemiology / Q000517:prevention & control; D015914:Estrogen Replacement Therapy / Q000379:methods / Q000639:trends; D004967:Estrogens / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D015994:Incidence; D008055:Lipids / Q000097:blood; D017698:Postmenopause / Q000187:drug effects* / Q000378:metabolism
D004967:Estrogens; D008055:Lipids