Pregnancy in infertile PCOD patients. Complications and outcome.
OBJECTIVE
To evaluate the complications and outcome of pregnancy in women with polycystic ovary disease (PCOD).


METHODS
The course and outcome of 47 singleton pregnancies in women with well-documented PCOD were compared with those in 100 healthy controls.


RESULTS
Women with PCOD had a significantly higher body mass index as compared to the control group (P < .05); however, the proportion of lean versus obese subjects in the two groups was similar. The incidence of an abnormal glucose challenge test, gestational diabetes mellitus and pregnancy-induced hypertension was significantly increased in pregnant women with PCOD (P < .05). When lean PCOD subjects were compared with lean control subjects, the difference in the incidence of the above complications was still significant (P < .05). The incidence of pregnancy complications was similar when obese PCOD subjects were compared with obese controls.


CONCLUSIONS
Women with PCOD were at increased risk of gestational diabetes and pregnancy-induced hypertension, and this risk appeared to be independent of body mass index.
Urman
B
B
Department of Obstetrics and Gynecology, University of Hacettepe, Faculty of Medicine, Ankara, Turkey.
Sarac
E
E
Dogan
L
L
Gurgan
T
T
D000328:Adult; D015992:Body Mass Index; D002996:Clomiphene / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D016640:Diabetes, Gestational / Q000209:etiology; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D005951:Glucose Tolerance Test; D006801:Humans; D006973:Hypertension / Q000209:etiology; D007247:Infertility, Female / Q000209:etiology* / Q000628:therapy; D008596:Menotropins / Q000627:therapeutic use; D010062:Ovulation Induction; D011085:Polycystic Ovary Syndrome / Q000150:complications*; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome
D002996:Clomiphene; D008596:Menotropins; D003907:Dexamethasone