Size at birth, maternal nutritional status in pregnancy, and blood pressure at age 17: population based analysis.
OBJECTIVE
To assess the effect of size at birth, maternal nutrition, and body mass index on blood pressure in late adolescence.


METHODS
Population based analysis of birth weight corrected for gestational age, mother's weight before pregnancy and weight gain in pregnancy, obtained from the Jerusalem perinatal study, and blood pressure and body mass index at age 17, available from military draft records.


METHODS
Jerusalem, Israel.


METHODS
10,883 subjects (6684 men and 4199 women) born in Jerusalem during 1974-6 and subsequently drafted to the army.


METHODS
Systolic and diastolic blood pressures measured at age 17 and their correlation with birth weight, size at birth, mother's body mass index and weight gain during pregnancy, and height and weight at age 17.


RESULTS
Systolic and diastolic blood pressures were significantly and positively correlated with body weight, height, body mass index at age 17, and with mother's body weight and body mass index before pregnancy, but not with birth weight or mother's weight gain in pregnancy.


CONCLUSIONS
Variables reflecting poor intrauterine nutrition, including low maternal body mass index before pregnancy, poor maternal weight gain in pregnancy, and being born small for gestational age, were not associated with a higher blood pressure in late adolescence.
Laor
A
A
Department of Internal Medicine, Carmel Hospital, Haifa, Israel.
Stevenson
D K
DK
Shemer
J
J
Gale
R
R
Seidman
D S
DS
D000293:Adolescent; D001724:Birth Weight / Q000502:physiology; D001794:Blood Pressure / Q000502:physiology*; D001824:Body Constitution; D015992:Body Mass Index; D001835:Body Weight / Q000502:physiology; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn / Q000502:physiology*; D008297:Male; D009752:Nutritional Status / Q000502:physiology*; D011247:Pregnancy / Q000502:physiology*; D011297:Prenatal Exposure Delayed Effects; D012044:Regression Analysis