title: Multifocal gastric neoplasia after recurrent laser therapy for the watermelon stomach.
abstract: Repeated laser therapy has become an accepted therapeutic approach in the treatment of watermelon stomach, and to date no important negative sequelae have been reported. The case of a patient who underwent repeated sessions of neodymium: yttrium aluminum garnet (Nd:YAG) laser therapy over a five-year period for the treatment of the watermelon stomach is presented. Postlaser therapy the patient developed deep ulcerations that would heal; however, he ultimately developed a nodular antrum. Random biopsies of antral nodules revealed carcinoma-in-situ. A Billroth I gastrectomy revealed two foci of carcinoma-in-situ/high grade dysplasia and multiple foci of lower grades of dysplasia. This case suggests a possible association between use of laser therapy and development of gastric neoplasia.
authors.affiliation: Department of Medicine, University of Manitoba, Winnipeg. cbernst@cc.umanitoba.ca
authors.forename: C N
authors.initials: CN
authors.lastname: Bernstein
authors.forename: N
authors.initials: N
authors.lastname: Pettigrew
authors.forename: K K
authors.initials: KK
authors.lastname: Wang
authors.forename: H
authors.initials: H
authors.lastname: Greenberg
authors.forename: J
authors.initials: J
authors.lastname: Lipschitz
mesh_terms: D000368:Aged; D002278:Carcinoma in Situ / Q000209:etiology* / Q000473:pathology; D006471:Gastrointestinal Hemorrhage / Q000601:surgery*; D006801:Humans; D017075:Laser Coagulation / Q000009:adverse effects*; D008297:Male; D011706:Pyloric Antrum / Q000098:blood supply* / Q000473:pathology; D013274:Stomach Neoplasms / Q000209:etiology* / Q000473:pathology; D014652:Vascular Diseases / Q000473:pathology / Q000601:surgery