title: Clinical manifestations of Kashin-Beck disease in Nyemo Valley, Tibet.
abstract: Clinical manifestations of Kashin-Beck disease have been studied in Central Tibet. Statistical analysis of physical signs allowed a definition of the clinical diagnosis and a scale for the functional severity for the disease to be drawn up. This classification is used for the assessment of patients who received palliative physical treatment. A group of 136 patients have been examined and their disabled joints classified according to pain, bony enlargement and restriction of movement. 57% were between 20 and 35 years of age. The patients mainly complained about their distal weightbearing joints. The clinical evolution of the disease is described from childhood to adult life.
authors.affiliation: Médecins sans Frontières, Lhasa, Tibet Autonomous Region.
authors.forename: F
authors.initials: F
authors.lastname: Mathieu
authors.forename: F
authors.initials: F
authors.lastname: Begaux
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Lan
authors.forename: C
authors.initials: C
authors.lastname: Suetens
authors.forename: M
authors.initials: M
authors.lastname: Hinsenkamp
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D001827:Body Height; D002648:Child; D002675:Child, Preschool; D003906:Developing Countries; D019353:Endemic Diseases; D005260:Female; D006130:Growth Disorders / Q000453:epidemiology* / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D016059:Range of Motion, Articular / Q000502:physiology; D012307:Risk Factors; D012424:Rural Population; D017678:Sex Distribution; D018609:Tibet / Q000453:epidemiology; D016474:Weight-Bearing / Q000502:physiology