Metastatic anterior chamber non-Hodgkin lymphoma in a patient with acquired immunodeficiency syndrome.
OBJECTIVE
To alert ophthalmologists to the possibility of metastatic anterior chamber intraocular non-Hodgkin lymphoma in patients with acquired immunodeficiency syndrome (AIDS).


METHODS
We examined a 19-year-old man with AIDS who had an anterior uveitis with pseudohypopyon and a history of 2 months of malaise. A specimen of the lesion was obtained with a 25-gauge needle for pathologic examination.


RESULTS
Systemic exploration showed hepatomegaly. Abdominal computed tomography showed multiple lesions in the liver and spleen. Fine-needle aspiration disclosed a high-grade non-Hodgkin lymphoma. The result of a fine-needle aspiration obtained from a lesion in the anterior chamber was consistent with the same diagnosis.


CONCLUSIONS
An anterior chamber pseudohypopyon with uveitis can be the manifesting sign of a systemic lymphoma in a patient with AIDS and requires a thorough systemic evaluation.
España-Gregori
E
E
Department of Optics, University of Valencia, Spain.
Hernández
M
M
Menezo-Rozalén
J L
JL
Díaz-Llopis
M
M
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D000867:Anterior Chamber; D001707:Biopsy, Needle; D005134:Eye Neoplasms / Q000150:complications* / Q000473:pathology / Q000556:secondary*; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000150:complications* / Q000473:pathology; D008297:Male