24(24(1))[Z]-dehydroamarasterone B, a phytoecdysteroid from seeds of Leuzea carthamoides.
A new phytoecdysteroid, 24(24(1))[Z]-dehydroamarasterone B, has been isolated from seeds of Leuzea (Rhaponticum) carthamoides. It has been unambiguously identified by CIMS, 13C NMR and 1H NMR spectroscopy. The biological activity of the ecdysteroid has been determined in the Drosophila melanogaster BII bioassay. The ED50 (5.2 x 10(-7) M) is 70-fold higher than that for 20-hydroxyecdysone (7.5 x 10(-9) M).
Baltayev
U A
UA
Institute of Petrochemistry and Catalysis, Bashkortostan Republic Academy of Sciences, Russia.
Dinan
L
L
Girault
J P
JP
Lafont
R
R
D000818:Animals; D002460:Cell Line; D004331:Drosophila melanogaster / Q000166:cytology / Q000187:drug effects*; D026461:Ecdysteroids; D007301:Insect Hormones / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D010944:Plants / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D013256:Steroids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D013265:Stigmasterol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
C107977:24(24')-dehydroamarasterone B; D026461:Ecdysteroids; D007301:Insect Hormones; D013256:Steroids; D013265:Stigmasterol