title: [Hereditary nervous system diseases in Mordovia].
abstract: A medical genetic study on hereditary neural diseases was performed in 21 districts of the Mordovian Republic. The total number of persons examined was 936,800. The population load of autosomal dominant, autosomal recessive, and X-linked recessive diseases was 0.1696 +/- 0.0129, 0.1075 +/- 0.0107, and 0.0341 +/- 0.0010, respectively. Twenty-eight disease entities were revealed, including 10 autosomal recessive (AR), 15 autosomal dominant (AD), 2 X-linked recessive (XR) diseases, and 1 genetically heterogenous disease. These diseases were nonuniformly distributed among different populations of Mordovia. The incidence of AR diseases was highest in the Mordovian and Tatar populations; that of AD diseases, in the Russian population; and that of XR diseases, in the Mordovian population.
authors.forename: A N
authors.initials: AN
authors.lastname: Petrin
authors.forename: A V
authors.initials: AV
authors.lastname: Perepelov
authors.forename: S D
authors.initials: SD
authors.lastname: Nurbaev
authors.forename: E V
authors.initials: EV
authors.lastname: Balanovskaia
authors.forename: V F
authors.initials: VF
authors.lastname: Sitnikov
authors.forename: V S
authors.initials: VS
authors.lastname: Inozemtseva
authors.forename: G E
authors.initials: GE
authors.lastname: Rudenskaia
mesh_terms: D017517:Commonwealth of Independent States / Q000453:epidemiology; D005006:Ethnicity; D005799:Genes, Dominant; D005808:Genes, Recessive; D008040:Genetic Linkage; D006801:Humans; D009422:Nervous System Diseases / Q000453:epidemiology / Q000208:ethnology / Q000235:genetics*; D014960:X Chromosome