title: Complete remission of extensive metastatic renal cancer following immunotherapy.
abstract: The authors describe the case history of a 54-year-old female patient, who presented with breathlessness, deteriorating general health and a 12 kg weight loss due to extensive metastatic renal cancer. Pulmonary emboli complicated the presentation. The patient entered a remarkable complete radiological remission by 18 weeks following the introduction of interleukin-2/alpha-interferon immunotherapy. The possibility of immediate nephrectomy or warfarin contributing to the augmentation of the effects of the immunotherapy is discussed.
authors.affiliation: St Bartholomew's Hospital, Department of Radiotherapy/Clinical Oncology, London, UK.
authors.forename: P N
authors.initials: PN
authors.lastname: Plowman
authors.forename: J
authors.initials: J
authors.lastname: Costello
authors.forename: N
authors.initials: N
authors.lastname: O'Donoghue
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging / Q000556:secondary / Q000628:therapy*; D005260:Female; D006801:Humans; D007167:Immunotherapy; D016898:Interferon-alpha / Q000627:therapeutic use*; D007376:Interleukin-2 / Q000627:therapeutic use*; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D008875:Middle Aged; D009392:Nephrectomy; D011859:Radiography; D012074:Remission Induction; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D000970:Antineoplastic Agents; D016898:Interferon-alpha; D007376:Interleukin-2; D014859:Warfarin