title: Idiopathic hypereosinophilic syndrome presenting as cholestatic liver disease.
abstract: We report the case of a 34-year-old white man with recurrent episodes of abdominal pain, cholestasis and eosinophilia. The diagnosis of idiopathic hypereosinophilic syndrome (IHS) was made after exclusion of all known causes of eosinophilia. Liver biopsy revealed an eosinophilic infiltrate with biliary damage. The patient recovered after prednisolone treatment. We review the literature on the association between IHS and liver disease.
authors.affiliation: Department of Medicine 2, University Hospital of Santa Maria, Lisbon, Portugal.
authors.forename: A I
authors.initials: AI
authors.lastname: Valente
authors.forename: H C
authors.initials: HC
authors.lastname: Pinto
authors.forename: F
authors.initials: F
authors.lastname: Ramalho
authors.forename: P F
authors.initials: PF
authors.lastname: Cabrita
authors.forename: C
authors.initials: C
authors.lastname: Catarino
authors.forename: F
authors.initials: F
authors.lastname: Serejo
authors.forename: A
authors.initials: A
authors.lastname: Baptista
authors.forename: A
authors.initials: A
authors.lastname: Saragoça
authors.forename: O
authors.initials: O
authors.lastname: Bordalo
authors.forename: M C
authors.initials: MC
authors.lastname: Moura
mesh_terms: D000328:Adult; D002779:Cholestasis / Q000175:diagnosis*; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D008107:Liver Diseases / Q000175:diagnosis*; D008297:Male; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D011239:Prednisolone