title: Focal myasthenia gravis in a dog.
abstract: A 10-month-old American cocker spaniel was evaluated for megaesophagus, aspiration pneumonia, but no appendicular muscle weakness. During hospitalization, weakness of the facial muscles developed, this resolved with anticholinesterase administration. Serum antibodies against acetylcholine receptors were documented, confirming the diagnosis of focal myasthenia gravis. Diagnosis, management, and medical treatment are discussed.
authors.affiliation: Department of Veterinary Internal Medicine, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon.
authors.forename: A A
authors.initials: AA
authors.lastname: Webb
authors.forename: S M
authors.initials: SM
authors.lastname: Taylor
authors.forename: L
authors.initials: L
authors.lastname: McPhee
mesh_terms: D000818:Animals; D001323:Autoantibodies / Q000097:blood / Q000276:immunology; D002800:Cholinesterase Inhibitors / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000097:blood / Q000175:diagnosis* / Q000188:drug therapy; D004285:Dogs; D004931:Esophageal Achalasia / Q000175:diagnosis / Q000662:veterinary; D007037:Hypothyroidism / Q000175:diagnosis / Q000662:veterinary; D008297:Male; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000188:drug therapy / Q000662:veterinary*; D009388:Neostigmine / Q000627:therapeutic use; D011950:Receptors, Cholinergic / Q000276:immunology
chemical_list: D001323:Autoantibodies; D002800:Cholinesterase Inhibitors; D011950:Receptors, Cholinergic; D009388:Neostigmine