[Evaluation of the efficacy of immunotherapy with allergovit and catalet in patients with hay fever--multidrug evaluations].
The aim of this study was to compare the efficacy of the immunotherapy by Allergovit and Catalet. 699 patient in age 5-56 were desensitized. 213 were given Allergovit: 137 in one season, 56 in two seasons and 20 in three seasons and 484 were given Catalet: 288 in one season, 151 in two seasons and 45 in three seasons. The Catalet vaccine contains 12 grasses, rye and plantain pollen, but Allergovit contains a group of grass pollen-60% and rye pollen-40%. Qualification to the desensensitization was performed on the ground of clinics symptoms, positive (+ + + +) prick skin tests, of specific antibody IgE, positive provocation nose test presence and symptoms connected with pollen fall checked every day in the area of Poznań, Lódź and Katowice city. Estimation of the immunotherapy efficiency was assessed by patients, who noted their remarks in prepared "Patient card" using enclose score. In result of desensitization by Allergovit we achieved good and very good improvement (0 + 1 score) after one desensitization season in 77.3% patients, after two seasons in 85.7% and after three seasons in 90.0%, on the contrary by patients desensibilized by Catalet results good and very good were achieved in 50% after one season, after two seasons in 63.6% and after three seasons in 77.8%.


CONCLUSIONS
Better results were achieved in patients desensibilized by Allergovit than Catalet. It is necessary of compose the contain of Catalet vaccine for every patient.
Hofman
T
T
Centrum Alergologii w Poznaniu.
Buczyłko
K
K
Brewczyński
P
P
Kolasińska
B
B
D000293:Adolescent; D000328:Adult; D000485:Allergens / Q000008:administration & dosage*; D001985:Bronchial Provocation Tests; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007167:Immunotherapy; D008875:Middle Aged; D006255:Rhinitis, Allergic, Seasonal / Q000175:diagnosis / Q000628:therapy*; D012621:Seasons; D012882:Skin Tests; D016896:Treatment Outcome; D014612:Vaccines; D014614:Vaccines, Synthetic / Q000008:administration & dosage*
D000485:Allergens; D014612:Vaccines; D014614:Vaccines, Synthetic; C099681:allergovit; C082987:catalet