title: [Cost increase due to incorrect antibiotic prophylaxis in visceral, thoracic and vascular surgery].
abstract: We analysed retrospectively 460 patients treated between March 1991 and February 1992, in respect to a correct perioperative antibiotic prophylaxis. In our opinion a correct prophylaxis is a single-shot application, with a second dose given only during long operations (over 3 hours) or when blood loss is great. 240 of the 460 patients analysed (52.2%) were given antibiotics prophylactically. In 76.6% of the cases (n = 184) the prophylaxis was performed correctly. In 23.4% (n = 56) antibiotic application was extended indiscriminately into the post-operative phase. This calculated to costs three times higher than those actually necessary, causing us to spend 22,000-Swiss francs unnecessarily, one twelfth of the total cost of antibiotic treatment in our hospital each year. For economic reasons as well as to keep growth of resistant strains in check, an antibiotic prophylaxis should be restricted to the perioperative period in most cases as a single shot only.
authors.affiliation: Klinik für Chirurgie, Kantonsspital St. Gallen.
authors.forename: R
authors.initials: R
authors.lastname: Zengaffinen
authors.forename: J
authors.initials: J
authors.lastname: Lange
mesh_terms: D000005:Abdomen / Q000601:surgery*; D019072:Antibiotic Prophylaxis / Q000191:economics*; D002435:Cefamandole / Q000008:administration & dosage / Q000191:economics; D002511:Cephalosporins / Q000008:administration & dosage / Q000191:economics; D003365:Costs and Cost Analysis; D005260:Female; D006300:Health Services Misuse / Q000191:economics*; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D013557:Switzerland; D013903:Thoracic Surgery / Q000191:economics*; D014656:Vascular Surgical Procedures / Q000191:economics*
chemical_list: D002511:Cephalosporins; D002435:Cefamandole