Lack of detection of myocardial injury during competitive races of 100 miles lasting 18 to 30 hours.
Competitors in an ultramarathon performed under extreme conditions did not demonstrate evidence of subclinical myocardial injury, as determined using cardiac troponin T as a marker. This finding refutes previous data and is likely due to utilization of an improved assay for cardiac troponin T that minimizes cross reactivity with skeletal muscle troponin T.
Laslett
L
L
Division of Cardiovascular Medicine, University of California, Davis Medical Center, Sacramento 95817, USA.
Eisenbud
E
E
D015415:Biomarkers / Q000032:analysis*; D003402:Creatine Kinase / Q000097:blood; D006801:Humans; D007118:Immunoassay / Q000379:methods; D007527:Isoenzymes; D009206:Myocardium / Q000473:pathology*; D010807:Physical Endurance / Q000502:physiology*; D012420:Running / Q000502:physiology*; D014336:Troponin / Q000032:analysis*; D020107:Troponin T
D015415:Biomarkers; D007527:Isoenzymes; D014336:Troponin; D020107:Troponin T; D003402:Creatine Kinase