Free radical mediated sperm-load management in the vagina of rats.
The postcoitus phagocytic engulfment of spermatozoa following disintegration of a sperm cell has not been well understood until now. By monitoring the free radical status of the vagina in accordance with the various stages of the estrous cycle and the sperm-cutting power of vaginal flushing, a positive correlation has been detected that favors the superoxide theory of the sperm-cutting technique in vivo. This finding is also consistent with the previous experience of free radical bombing of spermatozoa in spermatic granuloma.
Chatterjee
S
S
Department of Physiology, Himalayan Institute of Medical Sciences, Jolly Grant, Dehradoon, India.
Reddy
A L
AL
Laloraya
M
M
Kumar
P G
PG
D000818:Animals; D000838:Anions; D004031:Diestrus; D004971:Estrus; D005260:Female; D005609:Free Radicals; D008297:Male; D008855:Microscopy, Electron, Scanning; D010586:Phagocytes / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar; D013094:Spermatozoa / Q000502:physiology* / Q000648:ultrastructure; D013482:Superoxide Dismutase / Q000378:metabolism; D013481:Superoxides / Q000378:metabolism*; D014621:Vagina / Q000166:cytology* / Q000378:metabolism
D000838:Anions; D005609:Free Radicals; D013481:Superoxides; D013482:Superoxide Dismutase