Sodium transporters in health and disease.
Our understanding of sodium transport defects has exploded in the past 18 months, and has provided unique insights into epithelial transport processes and unusual clinical syndromes resulting from mutations of specific transporters. These genetic disorders disturb sodium balance, with both sodium retaining and sodium wasting disorders as the consequence.
Warnock
D G
DG
Department of Medicine, University of Alabama at Birmingham 35294-0007, USA. dwarnock@nrtc.dom.uab edu
D000818:Animals; D001477:Bartter Syndrome / Q000235:genetics / Q000378:metabolism; D002118:Calcium / Q000652:urine; D002712:Chlorides / Q000378:metabolism; D003967:Diarrhea / Q000151:congenital / Q000235:genetics / Q000378:metabolism; D004848:Epithelium / Q000378:metabolism; D005260:Female; D006801:Humans; D007008:Hypokalemia / Q000235:genetics / Q000378:metabolism; D007015:Hypophosphatemia, Familial / Q000235:genetics / Q000378:metabolism; D007231:Infant, Newborn; D007669:Kidney Calculi / Q000235:genetics / Q000378:metabolism; D008297:Male; D051379:Mice; D011546:Pseudohypoaldosteronism / Q000145:classification / Q000235:genetics / Q000378:metabolism; D015222:Sodium Channels / Q000235:genetics / Q000378:metabolism*; D013577:Syndrome
D002712:Chlorides; D015222:Sodium Channels; D002118:Calcium