title: [Synthesis of triterpene 2-deoxy-alpha-D-hexopyranosides on the basis of glycals and their effect on reparative processes].
abstract: Triterpene 2-deoxy-alpha-D-hexopyranosides were synthesized by the glycosylation of oleanane triterpene alcohols with D-glucal and D-galactal acetates in the presence of di(sym-collidine)iodonium perchlorate with subsequent deiodination and deacetylation of the resulting 2-deoxy-2-iodo-alpha-D-glycosides. 2-Deoxy-alpha-D-arabino- and -lyxo-hexopyranosides of methyl glycyrrhetinate demonstrated pronounced antiulcer activity and stimulated reparative skin regeneration in rats more effectively than glycyrrhizic acid and methyluracil.
authors.forename: L A
authors.initials: LA
authors.lastname: Baltina
authors.forename: O B
authors.initials: OB
authors.lastname: Flekhter
authors.forename: E V
authors.initials: EV
authors.lastname: Vasil'eva
authors.forename: V A
authors.initials: VA
authors.lastname: Davydova
authors.forename: A F
authors.initials: AF
authors.lastname: Ismagilova
authors.forename: F S
authors.initials: FS
authors.lastname: Zarudi'i
authors.forename: G A
authors.initials: GA
authors.lastname: Tolstikov
mesh_terms: D000818:Animals; D000897:Anti-Ulcer Agents / Q000138:chemical synthesis*; D003879:Dermatologic Agents / Q000138:chemical synthesis*; D006027:Glycosides / Q000138:chemical synthesis* / Q000494:pharmacology; D051381:Rats; D012867:Skin / Q000293:injuries; D013329:Structure-Activity Relationship; D014945:Wound Healing / Q000187:drug effects
chemical_list: D000897:Anti-Ulcer Agents; D003879:Dermatologic Agents; D006027:Glycosides