[Helicobacter pylori infection in developing countries].
Helicobacter pylori infection is probably the most common bacterial infection in the world. The pathogenicity of this bacteria has been recognized since 1989 in the developed world where prevalence is 20 to 40%. Its role in gastric and duodenal disease is certain and its low recurrence rate justifies eradication. In the developing world prevalence of Helicobacter pylori infection is over 80% with contamination being maximal in children. Transmission is oro-oral and even feco-oral. Crowded living conditions is the determinant factor. Helicobacter pylori infection exhibits special features in developing world. The prevalence of gastroduodenal disease varies according to geographic area independently of the prevalence of Helicobacter pylori infection and stomach cancer is uncommon. In newborns Helicobacter pylori infection seems to be the primary event for chronic malnutrition and diarrhea syndrome with failure to thrive. In practice detection of Helicobacter pylori is difficult in the developing world and presumptive treatment is always followed by recurrence. In the future active or passive immunization will be the solution.
Guisset
M
M
Service d'Hépato-Gastro-Entérologie, Hôpital d'Instruction des Armées Laveran, Marseille, France.
Coton
T
T
Rey
P
P
Debonne
J M
JM
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D003906:Developing Countries / Q000706:statistics & numerical data*; D003968:Diarrhea, Infantile / Q000453:epidemiology / Q000382:microbiology; D004378:Duodenal Diseases / Q000453:epidemiology / Q000382:microbiology; D005183:Failure to Thrive / Q000453:epidemiology / Q000382:microbiology; D005243:Feces / Q000382:microbiology; D005544:Forecasting; D016481:Helicobacter Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy / Q000635:transmission; D016480:Helicobacter pylori / Q000472:pathogenicity; D006801:Humans; D007114:Immunization; D007116:Immunization, Passive; D007231:Infant, Newborn; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology; D009748:Nutrition Disorders / Q000453:epidemiology / Q000382:microbiology; D015995:Prevalence; D012008:Recurrence; D012111:Residence Characteristics; D012924:Social Conditions; D013272:Stomach Diseases / Q000453:epidemiology / Q000382:microbiology; D013274:Stomach Neoplasms / Q000453:epidemiology / Q000382:microbiology; D014774:Virulence