title: [Two kinds of cytokine gene expression in umbilical cord blood of premature and mature neonates].
abstract: OBJECTIVE
  To study the immunological function of premature and mature neonates.
  
  
  METHODS
  By means of in situ hybridization technique, mRNA expression of interleukin-1 (IL-1) beta and IL-1r alpha in umbilical cord blood of 34 cases was analyzed.
  
  
  RESULTS
  It showed that mRNA expression of IL-1 beta and IL-1r alpha were significantly lower in the group of preterm vaginal delivery resulting from premature rupture of membranes than that of preterm cesarean section with the indication of pregnancy induced hypertension and than that of full term delivery (P < 0.001). No significant difference was found between the latter 2 groups.
  
  
  CONCLUSIONS
  It indicated that gene expression of IL-1 beta and IL-1r alpha probably related to the fetal maturity.
authors.affiliation: People's Hospital, Beijing Medical University.
authors.forename: J
authors.initials: J
authors.lastname: Tang
authors.forename: P
authors.initials: P
authors.lastname: Zhang
authors.forename: F
authors.initials: F
authors.lastname: Liu
mesh_terms: D000328:Adult; D005260:Female; D005312:Fetal Blood / Q000378:metabolism*; D015870:Gene Expression; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature / Q000097:blood / Q000276:immunology*; D053590:Interleukin 1 Receptor Antagonist Protein; D007375:Interleukin-1 / Q000235:genetics*; D053583:Interleukin-1beta; D010446:Peptide Fragments / Q000235:genetics*; D011247:Pregnancy; D012333:RNA, Messenger / Q000378:metabolism*; D012795:Sialoglycoproteins / Q000235:genetics*
chemical_list: C507763:IL1RN protein, human; D053590:Interleukin 1 Receptor Antagonist Protein; D007375:Interleukin-1; D053583:Interleukin-1beta; D010446:Peptide Fragments; D012333:RNA, Messenger; D012795:Sialoglycoproteins; C052994:interleukin-1beta (163-171)