title: Effect of anorectal eversion on long-term clinical outcome of restorative proctocolectomy.
abstract: Eversion of the rectum during restorative proctocolectomy with stapled ileal pouch-anal anastomosis (IPAA) remains a controversial surgical manoeuvre because of concern that it may impair anal sphincter function and adversely affect outcome. We have reviewed the long-term results in 41 patients whose operation included formation of a 20 cm J-pouch with stapled IPAA by the technique of rectal eversion. At median follow-up of 4 years (range 1-6 years), 4 pouches (10%) had been removed (2 for pelvic sepsis, 1 for rectovaginal fistula and 1 for Crohn's disease). In 34 patients with functioning pouches in situ, median stool frequency was 5 per 24 h (range 2-10). 11 patients (33%) regularly had to evacuate their pouch at night and 4 (12%) used antidiarrhoeal medication. No patients reported major incontinence; 2 (6%) had minor leakage, and in another 2 minor leakage had now ceased. 4 patients had had episodes of pouchitis. These favourable results offer no support for the contention that rectal eversion substantially worsens the long-term results of restorative proctocolectomy.
authors.affiliation: Department of Surgery, University Hospital of South Manchester, Chorley Hospital, Lancs, England.
authors.forename: D J
authors.initials: DJ
authors.lastname: DeFriend
authors.forename: M
authors.initials: M
authors.lastname: Mughal
authors.forename: R H
authors.initials: RH
authors.lastname: Grace
authors.forename: P F
authors.initials: PF
authors.lastname: Schofield
mesh_terms: D000293:Adolescent; D000328:Adult; D003672:Defecation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D016737:Proctocolectomy, Restorative / Q000379:methods*; D012007:Rectum / Q000601:surgery*; D018805:Sepsis; D017211:Treatment Failure; D016896:Treatment Outcome