title: Nephrotic syndrome resulting in thromboembolic disease and disseminated intravascular coagulation in a dog.
abstract: Thromboembolic disease and progression to disseminated intravascular coagulation (DIC) are potential life-threatening complications for dogs with nephrotic syndrome. Platelet count, prothrombin time (PT), activated partial thromboplastin time (APTT), plasma concentration of fibrinogen degradation products (FDPs), antithrombin III (ATIII), protein C, and plasminogen were used to identify hemostatic abnormalities in a dog with nephrotic syndrome. Pulmonary thromboembolic disease was diagnosed by thoracic radiography, arterial blood gas analysis, and pulmonary scintigraphy. Prompt recognition and treatment of hemostatic complications is necessary in dogs with nephrotic syndrome.
authors.affiliation: Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station 77843-4457, USA.
authors.forename: M G
authors.initials: MG
authors.lastname: Ritt
authors.forename: K S
authors.initials: KS
authors.lastname: Rogers
authors.forename: J S
authors.initials: JS
authors.lastname: Thomas
mesh_terms: D000818:Animals; D000990:Antithrombin III / Q000032:analysis / Q000378:metabolism; D001784:Blood Gas Analysis / Q000662:veterinary; D001786:Blood Glucose / Q000032:analysis; D001806:Blood Urea Nitrogen; D002784:Cholesterol / Q000097:blood; D003404:Creatinine / Q000097:blood; D018450:Disease Progression; D004211:Disseminated Intravascular Coagulation / Q000097:blood / Q000209:etiology / Q000662:veterinary*; D004283:Dog Diseases / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D004285:Dogs; D005340:Fibrinogen / Q000032:analysis / Q000378:metabolism; D008168:Lung / Q000000981:diagnostic imaging; D008297:Male; D009404:Nephrotic Syndrome / Q000097:blood / Q000150:complications / Q000662:veterinary*; D010314:Partial Thromboplastin Time; D010958:Plasminogen / Q000032:analysis / Q000378:metabolism; D010976:Platelet Count; D011486:Protein C / Q000032:analysis / Q000378:metabolism; D011517:Prothrombin Time; D011655:Pulmonary Embolism / Q000097:blood / Q000209:etiology / Q000662:veterinary*; D013902:Radiography, Thoracic / Q000379:methods / Q000662:veterinary; D011877:Radionuclide Imaging
chemical_list: D001786:Blood Glucose; D011486:Protein C; D000990:Antithrombin III; D005340:Fibrinogen; D010958:Plasminogen; D002784:Cholesterol; D003404:Creatinine