Linear IgA disease with clinical and immunopathological features of epidermolysis bullosa acquisita.
A 10-year-old boy had a 3-month history of urticarial plaques and vesicles. Histologic and immunofluorescence testing confirmed the diagnosis of linear IgA disease. Immunoelectron microscopy revealed IgA deposits in the sublamina densa area similar to those seen in epidermolysis bullosa acquisita. Milia developed after resolution of the lesions, similar to lesions of epidermolysis bullosa acquisita.
Mutasim
D F
DF
Department of Dermatology, University of Cincinnati, Ohio 45267-0523, USA.
Cummings
M P
MP
D001485:Basement Membrane / Q000276:immunology; D002648:Child; D003622:Dapsone / Q000627:therapeutic use; D006801:Humans; D007070:Immunoglobulin A / Q000032:analysis*; D008297:Male; D012867:Skin / Q000276:immunology* / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology
D007070:Immunoglobulin A; D003622:Dapsone