title: [Keratotic neurocutaneous syndromes].
abstract: OBJECTIVE
  To review current knowledge of etiologic, clinic, diagnostic and therapeutic aspects of ichthyotic diseases with neurologic manifestations.
  
  
  METHODS
  Classic keratotic neurocutaneous syndromes including Sjögren-Larsson syndrome, trichotyodystrophy, KID (keratitis, ichthyosis and deafness) syndrome and Rud syndrome, are reviewed. Furthermore, we pay attention to syndromes whose description and study are of current importance: cardiofaciocutaneous syndrome, neutral lipids storage disease with ichthyosis, multiple sulphatase deficiency disease and peroxisomal disorders.
  
  
  CONCLUSIONS
  Keratotic neurocutaneous syndromes knowledge will help to improve its diagnosis and therapeutic approach.
authors.affiliation: Sección de Dermatología, Hospital Universitario Virgen de las Nieves, Granada, España.
authors.forename: J
authors.initials: J
authors.lastname: Tercedor
authors.forename: A
authors.initials: A
authors.lastname: García
mesh_terms: D000326:Adrenoleukodystrophy / Q000175:diagnosis; D002806:Chondrodysplasia Punctata / Q000175:diagnosis; D003638:Deafness / Q000150:complications; D006801:Humans; D007057:Ichthyosis / Q000150:complications / Q000175:diagnosis*; D018901:Peroxisomal Disorders / Q000175:diagnosis*; D012035:Refsum Disease / Q000175:diagnosis; D016111:Sjogren-Larsson Syndrome / Q000175:diagnosis; D013577:Syndrome