Enveloped viruses: a common mode of membrane fusion?.
Viruses use elaborate stratagems to enter cells. The HIV-1 envelope glycoprotein, which mediates both attachment and membrane fusion, has grudgingly begun to yield high-resolution structural information that suggests mechanistic similarities with the hemagglutinin protein of influenza virus.
Hughson
F M
FM
Department of Molecular Biology, Princeton University, Princeton, New Jersey 08544, USA. fhughson@molbiol.princeton.edu
D000818:Animals; D015497:HIV-1 / Q000502:physiology; D019267:Hemagglutinin Glycoproteins, Influenza Virus / Q000502:physiology; D006801:Humans; D008561:Membrane Fusion; D008958:Models, Molecular; D009975:Orthomyxoviridae / Q000502:physiology; D014759:Viral Envelope Proteins / Q000502:physiology*; D014760:Viral Fusion Proteins / Q000502:physiology
D019267:Hemagglutinin Glycoproteins, Influenza Virus; D014759:Viral Envelope Proteins; D014760:Viral Fusion Proteins