title: Molecular intimacy between proteins specifying plant-pathogen recognition.
abstract: Disease resistance in plants is commonly specified by genetically paired plant resistance (R) and pathogen avirulence (Avr) proteins. Recent molecular analyses of several R-Avr protein interactions provide compelling evidence for a receptor-ligand mechanism in which specific binding of the Avr elicitor by its matching R protein leads to activation of the plant defence response. Direct R-Avr protein recognition precedes the function of an expanding battery of plant resistance signalling components.
authors.affiliation: Sainsbury Laboratory, Norwich Research Park, UK. parkerj@bbsrc.ac.uk
authors.forename: J E
authors.initials: JE
authors.lastname: Parker
authors.forename: M J
authors.initials: MJ
authors.lastname: Coleman
mesh_terms: D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D003001:Cloning, Molecular; D005656:Fungal Proteins / Q000235:genetics* / Q000378:metabolism; D005798:Genes, Bacterial / Q000235:genetics; D005800:Genes, Fungal / Q000235:genetics; D007113:Immunity, Innate / Q000235:genetics*; D010935:Plant Diseases; D010940:Plant Proteins / Q000235:genetics*; D010944:Plants / Q000235:genetics* / Q000382:microbiology; D015398:Signal Transduction
chemical_list: D001426:Bacterial Proteins; D005656:Fungal Proteins; D010940:Plant Proteins