title: A method for more efficient source localization of interstitial implants with biplane radiographs.
abstract: The conventional method for source localization in an interstitial ribbon implant by means of biplane radiographs can be difficult, especially when a large number of seeds are involved. We present a new algorithm for more efficient source localization with the same conventional biplane radiographs. The method does not require a one-to-one source correspondence between two radiographs. The user needs only to digitize several points, following the shape of each ribbon from both films. The points that are digitized do not need to be the location of the seeds, and they do not have to correspond to the same points on both films. The algorithm uses the multidimensional minimization method to reconstruct the three-dimensional locus of the ribbon. The location of each seed is then determined by its pathlength relative to the corresponding starting point. We have used phantom experiments and clinical cases to test the reliability of the algorithm. The results show that the errors in the determination of seed locations are less than 2 mm, and the efficiency in source digitization for data entry can be increased by a factor up to 5.
authors.affiliation: Department of Medical Physics, Rush Presbyterian St. Luke's Medical Center, Chicago, Illinois 60612, USA. cai@therad.rpslmc.edu
authors.forename: J
authors.initials: J
authors.lastname: Cai
authors.forename: J C
authors.initials: JC
authors.lastname: Chu
authors.forename: V A
authors.initials: VA
authors.lastname: Saxena
authors.forename: L H
authors.initials: LH
authors.lastname: Lanzl
mesh_terms: D055592:Biophysical Phenomena; D001703:Biophysics; D001918:Brachytherapy / Q000379:methods* / Q000706:statistics & numerical data; D005069:Evaluation Studies as Topic; D006801:Humans; D008962:Models, Theoretical; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy; D019047:Phantoms, Imaging; D011856:Radiographic Image Enhancement / Q000379:methods*; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods* / Q000706:statistics & numerical data