title: [Vasopressin: basic and clinical aspects].
abstract: Vasopressin (VP) is distributed in many parts of the brain. VP regulates the hypothalamo-pituitary-adrenal axis together with the corticotropin-releasing hormone. It closely follows a 24-h rhythm in the suprachiasmatic nucleus (SCN) and influences memory and behavior in the septum. clinical evidence suggests that VP might be related to depression and dementia. In this review, the central distribution of VP-containing cells, the physiological action of VP and related findings in depressed patients and demented patients are described.
authors.affiliation: Department of Psychiatry, Yamanashi Medical University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kubota
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000378:metabolism; D003704:Dementia / Q000209:etiology / Q000378:metabolism; D003863:Depression / Q000209:etiology / Q000378:metabolism; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology; D010286:Paraventricular Hypothalamic Nucleus / Q000378:metabolism; D010903:Pituitary Gland, Anterior / Q000378:metabolism; D010913:Pituitary-Adrenal System / Q000502:physiology; D017483:Receptors, Vasopressin / Q000378:metabolism; D013312:Stress, Physiological / Q000209:etiology / Q000378:metabolism; D013495:Supraoptic Nucleus / Q000378:metabolism; D014667:Vasopressins / Q000378:metabolism / Q000502:physiology
chemical_list: D017483:Receptors, Vasopressin; D014667:Vasopressins; D000324:Adrenocorticotropic Hormone