Torsade de pointes and prolonged QT interval from surreptitious use of sotalol: use of drug levels in diagnosis.
Torsade de pointes is a well-established toxic effect of sotalol hydrochloride. In a patient presenting with torsade de pointes and a long QTc interval of unknown cause, a serum sotalol level was used to secure an otherwise difficult diagnosis.
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Cardiac Arrhythmia Service, Tufts/New England Medical Center, Boston, MA 02111, USA.
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Sloan
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Homoud
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Wang
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D000328:Adult; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000097:blood / Q000506:poisoning*; D062787:Drug Overdose; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008133:Long QT Syndrome / Q000139:chemically induced* / Q000175:diagnosis; D013015:Sotalol / Q000008:administration & dosage / Q000097:blood / Q000506:poisoning*; D016171:Torsades de Pointes / Q000139:chemically induced* / Q000175:diagnosis
D000889:Anti-Arrhythmia Agents; D013015:Sotalol