Transient liver accumulation of Tc-99m phytate in hepatocellular carcinoma after percutaneous ethanol injection.
OBJECTIVE
We report that colloid liver scanning gave early evidence of the return to normal of Kupffer cell functions after ethanol injections into the liver.


METHODS
A 71-year-old man with hepatocellular carcinoma received percutaneous ethanol injections twice of 15 mL of ethanol, 1 week apart.


RESULTS
Abdominal CT after the second injection showed an irregularly shaped low-density area in the left side of the tumor, extending outside the tumor. Liver imaging with To-99m phytate 10 days later showed increased activity at the corresponding site. Thirty days after the second injection, liver imaging did not show high activity.


CONCLUSIONS
Ethanol that leaked into the normal part of the liver probably temporarily activated Kupffer cell function.
Shiomi
S
S
Third Department of Internal Medicine, Osaka City University Medical School, Japan.
Kuroki
T
T
Masaki
K
K
Sakaguchi
H
H
Takeda
T
T
Kuriyama
M
M
Tanaka
T
T
Ochi
H
H
D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D000431:Ethanol / Q000008:administration & dosage*; D006801:Humans; D007728:Kupffer Cells / Q000000981:diagnostic imaging / Q000187:drug effects; D008103:Liver Cirrhosis / Q000150:complications; D008113:Liver Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000188:drug therapy; D008297:Male; D015609:Organotechnetium Compounds; D010833:Phytic Acid; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals
D000970:Antineoplastic Agents; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C026177:technetium phytate; D000431:Ethanol; D010833:Phytic Acid