title: Detection of specific IgE to human milk proteins in sera of atopic infants.
abstract: Specific IgE (sIgE) for cow's milk proteins (CMP) have been reported to be present in blood sera of exclusively breast-fed infants. The aim of this study was to find whether the presence of sIgE to human milk proteins in the sera of exclusively breast-fed infants could explain the apparent detection of sIgE to CMP in infants that were never previously in contact with cow's milk. sIgE for human milk whey proteins were found in the blood sera of atopic infants, and these sIgE strongly cross-reacted with the corresponding CMP. In none of the sera examined were sIgE to bovine beta-lactoglobulin detected.
authors.affiliation: Centro Studio Alimentazione Animali, CNR, Torino, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Cantisani
authors.forename: M G
authors.initials: MG
authors.lastname: Giuffrida
authors.forename: C
authors.initials: C
authors.lastname: Fabris
authors.forename: E
authors.initials: E
authors.lastname: Bertino
authors.forename: A
authors.initials: A
authors.lastname: Coscia
authors.forename: R
authors.initials: R
authors.lastname: Oggero
authors.forename: G
authors.initials: G
authors.lastname: Monti
authors.forename: P
authors.initials: P
authors.lastname: Stroppiana
authors.forename: A
authors.initials: A
authors.lastname: Conti
mesh_terms: D000818:Animals; D000918:Antibody Specificity; D001666:Binding Sites, Antibody; D001667:Binding, Competitive / Q000276:immunology; D002417:Cattle / Q000276:immunology; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000097:blood / Q000209:etiology / Q000276:immunology*; D007073:Immunoglobulin E / Q000097:blood* / Q000378:metabolism; D007223:Infant; D008894:Milk Proteins / Q000276:immunology* / Q000378:metabolism; D008895:Milk, Human / Q000276:immunology*; D013045:Species Specificity
chemical_list: D008894:Milk Proteins; D007073:Immunoglobulin E