[Evaluation of fetal condition in pregnancy complicated by hypertension--biochemical assessment of amniotic fluid. I. Protein and lipid components and kidney maturation].
Sixty two samples of amniotic fluid were submitted to biochemical investigation including 31 samples from women with pregnancy complicated by hypertension (studied group with mean blood pressure 165 +/- 15/95 +/- 5 mmHg) and 31 samples deriving from healthy pregnant women (control group with mean blood pressure 118 +/- 10/74 +/- +/- 9 mmHg). In the studied group pregnancy induced hypertension, primary hypertension and nephrogenic hypertension scored 58%, 32% and 10% of cases respectively. Both investigated and control groups consisted of pregnant women with the same gestational age of 37 +/- 2 weeks (34-40 weeks). The following parameters of amniotic fluid were measured: 1) total protein, 2) albumin, 3) beta-lipoprotein, 4) cholesterol, 5) uric acid, 6) urea, 7) creatinine. Micromethods were used. Amniotic fluid deriving from women with pregnancy complicated by hypertension showed decreased concentrations of total protein, albumin and beta-lipoprotein. In pregnancy complicated by hypertension kidneys of the fetuses were estimated to be as mature as in the normal pregnancy within the same gestational age.
Smolarczyk
R
R
II Katedry i Kliniki Połoznictwa i Ginekologii Akademii Medycznej w Warszawie.
Wójcicka-Jagodzińska
J
J
Romejko
E
E
Czajkowski
K
K
Piekarski
P
P
Teliga-Czajkowska
J
J
Kuczyńcka-Sicińska
J
J
D000328:Adult; D000418:Albumins / Q000378:metabolism; D000653:Amniotic Fluid / Q000737:chemistry*; D002784:Cholesterol / Q000378:metabolism; D003404:Creatinine / Q000378:metabolism; D005260:Female; D006801:Humans; D006973:Hypertension / Q000378:metabolism*; D006977:Hypertension, Renal / Q000378:metabolism*; D007668:Kidney / Q000196:embryology*; D008077:Lipoproteins, LDL / Q000378:metabolism; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000378:metabolism*; D011263:Pregnancy Trimester, Third; D011506:Proteins / Q000378:metabolism; D014508:Urea / Q000378:metabolism; D014527:Uric Acid / Q000378:metabolism
D000418:Albumins; D008077:Lipoproteins, LDL; D011506:Proteins; D014527:Uric Acid; D014508:Urea; D002784:Cholesterol; D003404:Creatinine