Isolation of new anthracyclines 10-O-rhodosaminyl beta-rhodomycinone and beta-isorhodomycinone from mild-acid treated culture of obelmycin-producing Streptomyces violaceus.
Johdo
O
O
Central Research Laboratories, Mercian Corporation, Johnan, Fujisawa, Japan.
Yoshioka
T
T
Takeuchi
T
T
Yoshimoto
A
A
D000818:Animals; D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic / Q000096:biosynthesis* / Q000737:chemistry / Q000302:isolation & purification*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D006863:Hydrogen-Ion Concentration; D007939:Leukemia L1210 / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D051379:Mice; D009279:Naphthacenes / Q000737:chemistry / Q000302:isolation & purification* / Q000378:metabolism; D013302:Streptomyces / Q000737:chemistry* / Q000378:metabolism*
D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic; D009279:Naphthacenes; C107812:10-O-rhodosaminyl beta-rhodomycinone; C107811:obelmycin H; C042916:beta-isorhodomycinone