title: Plasma endothelin-1 and tumor necrosis factor-alpha concentrations in pregnant and cyclic rats after low-dose endotoxin infusion.
abstract: Plasma endothelin-1 and tumor necrosis factor-alpha were determined in pregnant and cyclic rats after infusion of either endotoxin (1.0 microgram/kg of body weight) or saline solution. After endotoxin, but not after saline solution, administration there was a transient endothelin-1 response in pregnant rats but not cyclic rats. In both reproductive conditions there was an equally high transient tumor necrosis factor-alpha response after endotoxin.
authors.affiliation: Department of Obstetrics and Gynecology, University of Groningen, The Netherlands.
authors.forename: M M
authors.initials: MM
authors.lastname: Faas
authors.forename: W W
authors.initials: WW
authors.lastname: Bakker
authors.forename: N
authors.initials: N
authors.lastname: Valkhof
authors.forename: J F
authors.initials: JF
authors.lastname: Baller
authors.forename: G A
authors.initials: GA
authors.lastname: Schuiling
mesh_terms: D000818:Animals; D019332:Endothelin-1 / Q000097:blood*; D004731:Endotoxins / Q000008:administration & dosage*; D004971:Estrus / Q000502:physiology*; D005260:Female; D007700:Kinetics; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000097:blood*; D051381:Rats; D017208:Rats, Wistar; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism*
chemical_list: D019332:Endothelin-1; D004731:Endotoxins; D014409:Tumor Necrosis Factor-alpha