title: Effect of tea decoction given to rats ad libitum for a relatively long time on body weight gains and iron, copper, zinc, magnesium concentrations in blood, liver, duodenum and spleen.
abstract: The aim of our study was to examine the influence of tea decoction given ad libitum for 15 days on body weight gains and on nonheme iron, copper, zinc and magnesium concentrations in the blood from a semisynthetic diet provided to healthy rats. We have also evaluated the reserves of these essential minerals in the liver, duodenum and spleen. Our findings indicate that the tea decoction significantly reduced the total body weight growth in the tea group as compared to the control group (p < 0.0001). The total body weight gains for the control and tea groups were 13.2 and 2.4%, respectively. On the other hand, our data show that the tea decoction significantly reduced nonheme iron concentration in the total blood by 31.8% (p < 0.001). Similarly, the reserve of iron stored in the liver and the duodenum declined more significantly by 57% (p < 1.10(-7) and 50.5% (p < 1.10(-6)). respectively. In contrast to the inhibitory effect on iron concentration and its stored reserve, tea decoction significantly increased zinc, copper and magnesium concentrations in the total blood. Zinc, copper and magnesium concentrations increased by 29.4 (p < 0.05), 69.0 (p < 0.001) and 48.7% (p < 0.001), respectively. Moreover, tea decoction treatment did not raise the reserve of zinc or copper significantly but it increased the reserve of magnesium stored in the liver (p < 0.05).
authors.affiliation: Ecole supérieure des Sciences et Techniques de la Santé de Tunis, Tunisie.
authors.forename: M
authors.initials: M
authors.lastname: Hamdaoui
authors.forename: A
authors.initials: A
authors.lastname: Hédhili
authors.forename: T
authors.initials: T
authors.lastname: Doghri
authors.forename: B
authors.initials: B
authors.lastname: Tritar
mesh_terms: D000818:Animals; D003300:Copper / Q000097:blood / Q000378:metabolism*; D004386:Duodenum / Q000378:metabolism; D007501:Iron / Q000097:blood / Q000378:metabolism*; D008099:Liver / Q000378:metabolism; D008274:Magnesium / Q000097:blood / Q000378:metabolism*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000378:metabolism; D013662:Tea; D015430:Weight Gain / Q000187:drug effects*; D015032:Zinc / Q000097:blood / Q000378:metabolism*
chemical_list: D013662:Tea; D003300:Copper; D007501:Iron; D008274:Magnesium; D015032:Zinc