[Effect of chrysotile-asbestos and zeolites dust on generations of reactive oxygen species by alveolar macrophages and granulocytes].
Different characteristics of the influence of dusts of chrysotile--asbestos, mordenite, erionite and klinoptilolite on the total generation of the active forms of oxygen by the alveolar macrophages and the generation of O2- and H2O2 by the granulocytes give the possibility to connect some of these characteristics with the peculiarity of biological action these dusts. It is discovered the most strong activating properties has the dust of chrysotile--asbestos, and the most cytotoxic effect has the dust of klinoptilolite.
Gusev
V A
VA
NII of Labor Medicine RAMN, Moscow.
Lomonosova
O S
OS
Velichkovskií
B T
BT
D000818:Animals; D017632:Asbestos, Serpentine / Q000494:pharmacology*; D002273:Carcinogens / Q000494:pharmacology*; D002682:Chinchilla; D004391:Dust; D006098:Granulocytes / Q000187:drug effects / Q000378:metabolism*; D016676:Macrophages, Alveolar / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D011817:Rabbits; D017382:Reactive Oxygen Species / Q000502:physiology*; D017641:Zeolites / Q000494:pharmacology*
D017632:Asbestos, Serpentine; D002273:Carcinogens; D004391:Dust; D017382:Reactive Oxygen Species; D017641:Zeolites