title: [Medical-social outcome of 59 infants born to addicted mothers].
abstract: BACKGROUND
  Follow up of children born to drug-addicted mothers is difficult because of social context. The aim of this study was to determine the precise outcome in a cohort of infants from two neonatal units. POPULATION AND METHODS; Analysis of perinatal and follow up data of 59 infants born to drug-addicted mothers, admitted from 1988 to 1993 in the neonatal units of Colombes and Neuilly.
  
  
  RESULTS
  Perinatal data: very poor social context; 100% addiction by opiates and very frequent polyintoxication; 21% HIV + mothers; 54% came later or not at all to prenatal care; 34% prematurity and 46% intrauterine growth retardation; 80% neonatal withdrawal symptoms. Precise follow up data is known for 95% of the infants at the age of 1 to 7 years: 5% died during the first year of life; 51% are living with their family (with or without their mother); 36% are in institutions or foster homes, and 8% are fully adopted; among 41 newborns discharged from neonatal unit to their mother, 34% have been secondarily placed by Child Protection Services. The only severe sequelae were not related to drug direct effect: 5 neurologic or respiratory chronic impairment related to prematurity, and 3 asymptomatic HIV + children; a few moderate behavioral problems appear to be related to social familial context. Among the 51 mothers, 6 died (5 by overdose) 19 are severely addicted, 10 have stopped addiction but 2 are HIV +, and 16 are lost to follow up.
  
  
  CONCLUSIONS
  Analysis of this cohort and of the literature suggest a need for changing our perinatal strategies to ameliorate medico-psycho-social care of these pregnancies, mothers and infants, with or without methadone maintenance programs; these strategies have been proved to prevent perinatal problems (specially prematurity), and to improve mother-infant attachment.
authors.affiliation: Service de Néonatologie, Hôpital Louis Mourier, Colombes.
authors.forename: C
authors.initials: C
authors.lastname: Lejeune
authors.forename: J C
authors.initials: JC
authors.lastname: Ropert
authors.forename: S
authors.initials: S
authors.lastname: Montamat
authors.forename: C
authors.initials: C
authors.lastname: Floch-Tudal
authors.forename: F
authors.initials: F
authors.lastname: Mazy
authors.forename: N
authors.initials: N
authors.lastname: Wijkhuisen
authors.forename: H
authors.initials: H
authors.lastname: Froment
mesh_terms: D000293:Adolescent; D000328:Adult; D002423:Cause of Death; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology*; D005500:Follow-Up Studies; D006301:Health Services Needs and Demand; D006801:Humans; D007231:Infant, Newborn; D008428:Maternal Mortality; D009357:Neonatal Abstinence Syndrome / Q000209:etiology*; D007752:Obstetric Labor, Premature / Q000209:etiology*; D011247:Pregnancy; D011248:Pregnancy Complications; D011256:Pregnancy Outcome; D011379:Prognosis; D012189:Retrospective Studies; D012923:Social Class; D019966:Substance-Related Disorders / Q000150:complications*