Alginate based new materials.
Present and future applications of alginates are mainly linked to the most striking feature of the alginate molecule; i.e. a sol/gel transition in the presence of multivalent cations, e.g. Ca2+, almost independent on temperature. These very mild conditions, combined with the fact that alginates are highly characterised and understood both in the liquid and in the gel phase, makes this biopolymer unique compared to other gelling polysaccharides. Only pectins resemble alginate in the sol/gel transition behaviour, but this system can hardly be said to be as well characterised and understood as the alginates. The properties of alginate solutions and gels suggest biomedical and pharmaceutical uses. In this paper, the question of the specifications required by a polymer for applications in some biomedical areas will be discussed.
Draget
K I
KI
Department of Biotechnology, Norwegian University of Science and Technology, Trondheim. KDRAGET@KJEMI.UNIT.NO
Skjåk-Braek
G
G
Smidsrød
O
O
D000464:Alginates / Q000737:chemistry*; D001672:Biocompatible Materials / Q000737:chemistry*; D002240:Carbohydrate Sequence; D004058:Diffusion; D004800:Enzymes, Immobilized; D005782:Gels; D008969:Molecular Sequence Data; D019736:Prostheses and Implants; D012996:Solutions
D000464:Alginates; D001672:Biocompatible Materials; D004800:Enzymes, Immobilized; D005782:Gels; D012996:Solutions