[Intestinal flora in renal allograft recipients].
OBJECTIVE
To explore the change of 10 kinds of intestinal flora in renal allograft recipients and its significance.


METHODS
Ten kinds of intestinal flora in faeces were investigated in 30 renal allograft recipients by Kang Bai's classification of flora, and compared with 100 patients with diarrhea and 30 normal controls.


RESULTS
The number of enteric bacilli in renal allograft recipients (8.5 +/- 1.0 CFU/g) was increased more markely than in the diarrhea patients (7.7 +/- 1.1 CFU/g, P < 0.01). The number of bacteroid (7.8 +/- 0.6 CFU/g), bifidobactercium (7.7 +/- 0.3 CFU/g), eubaclerium (7.2 +/- 0.6 CFU/g), and clostridium (7.8 +/- 0.5 CFU/g) in renal allograft recipients were decreased more markedly in than normal control (8.2 +/- 0.7 CFU/g, P < 0.01, 8.3 +/- 0.7 CFU/g, P < 0.01, 8.1 +/- 0.9 CFU/g, P < 0.01, 8.0 +/- 0.8 CFU/g, P < 0.01), but the number of Bifidobactercum was higher than that is the diarrhea patients (7.3 +/- 0.6 CFU/g, P < 0.01). The number of eubacterium was Lower than that in the diarrhea patients (7.7 +/- 0.8 CFU/g, P < 0.01). Among 30 renal allograft recipients 3 had constipation and 20 diarrhea. Two cases died of toxic shock with serious diarrhea because of imbalance of intestinal flora.


CONCLUSIONS
The imbalance of intestinal flora existes in the early stage of renal transplantation. It is characterized by anaerobic bacilli imabalance such as bifidobacteriam and may be a direct cause of intestinal infection as diarrhea.
Pan
G H
GH
Department of Urology, Nanfang Hospital, First Millitarg Medical University, Guangzhou.
Xu
G
G
Fu
S
S
D000293:Adolescent; D000328:Adult; D001644:Bifidobacterium / Q000302:isolation & purification*; D003967:Diarrhea / Q000382:microbiology*; D005260:Female; D006801:Humans; D007421:Intestine, Small / Q000382:microbiology*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009393:Nephritis / Q000601:surgery; D011183:Postoperative Complications / Q000382:microbiology*; D014511:Uremia / Q000601:surgery