title: HLA gene frequencies and migration in an Italian province.
abstract: HLA class I (HLA-A, HLA-B) and class II (HLA-DR, HLA-DQ) gene frequencies in 6 subareas of Pavia province are calculated in two samples of bone marrow donors. We estimated the degree of genetic differentiation between the 6 sub-areas through the standardized variance FST. On the basis of the island migration model the number of migrants is estimated from FST and compared with the observed migration index in the province according to the 1991 census.
authors.affiliation: Dipartimento di Genetica e Microbiologia, Università di Pavia, Italy.
authors.forename: A
authors.initials: A
authors.lastname: De Silvestri
authors.forename: M
authors.initials: M
authors.lastname: Martinetti
authors.forename: C
authors.initials: C
authors.lastname: Daielli
authors.forename: L
authors.initials: L
authors.lastname: Salvaneschi
authors.forename: M
authors.initials: M
authors.lastname: Cuccia
authors.forename: C R
authors.initials: CR
authors.lastname: Guglielmino
mesh_terms: D001856:Bone Marrow Examination; D005787:Gene Frequency; D005805:Genes, MHC Class I; D005802:Genes, MHC Class II; D006801:Humans; D007558:Italy; D019520:Living Donors; D014171:Transients and Migrants