title: Massive extra-enteric gastrointestinal hemorrhage secondary to splanchnic artery aneurysms.
abstract: OBJECTIVE
  Gastrointestinal hemorrhages of obscure origin are often difficult to diagnose and manage. Of these, splanchnic artery aneurysms have emerged as an important disorder because of the increasing prevalence and formidable mortality rate associated with their rupture. We herein evaluated extra-enteric gastrointestinal bleeding related to these ruptured aneurysms.
  
  
  METHODS
  The medical records of 17 patients with splanchnic artery aneurysms known to be exclusively manifested as gastrointestinal bleeding were reviewed. The pathogenesis, clinical picture, diagnostic tests, management, complications, and outcomes were compiled and analyzed.
  
  
  RESULTS
  Of the seventeen patients, 12 patients had true aneurysms; 5 patients had false aneurysms. Pancreatitis, trauma, iatrogenic hepatobiliary injury, and atherosclerosis were the four major etiologies. The sensitivity rates measured by endoscopy, ultrasonography, computed tomography and visceral angiography were 20%, 50%, 67%, and 100%, respectively. An exact diagnosis was attained in 94% of the patients at the time of management. Transcatheter embolization was employed in 7 patients, complicated with hepatic and splenic infarcts, and pyogenic liver abscesses in 2 instances. Two patients had recurrent bleeding aneurysms post embolotherapy. Ten patients underwent surgical intervention which resulted in 2 cases of hepatic failure. One out of 5 patients with a true aneurysm died, while 4 out of 12 patients with false aneurysms eventually died. Overall, the mortality rate was 29%.
  
  
  CONCLUSIONS
  Even though the exact diagnosis can be made in most of the patients by modern imaging studies, the mortality rate was still formidable, especially in patients with false aneurysms, in whom the underlying causal diseases substantially influenced the major outcome.
authors.affiliation: Department of Surgery, Chang Gung Memorial Hospital, Taiwan.
authors.forename: T S
authors.initials: TS
authors.lastname: Yeh
authors.forename: Y Y
authors.initials: YY
authors.lastname: Jan
authors.forename: L B
authors.initials: LB
authors.lastname: Jeng
authors.forename: T L
authors.initials: TL
authors.lastname: Hwang
authors.forename: C S
authors.initials: CS
authors.lastname: Wang
authors.forename: M F
authors.initials: MF
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017542:Aneurysm, Ruptured / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D000792:Angiography; D003131:Combined Modality Therapy; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005500:Follow-Up Studies; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D006801:Humans; D008297:Male; D008638:Mesenteric Arteries; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D013152:Splanchnic Circulation; D015996:Survival Rate; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome