Regional assignment of 64 human gene transcripts on chromosome 8.
A panel of somatic cell hybrids specific for human chromosome 8 was used to localize 64 expressed sequence-tagged site (ESTS) markers to six individual regions by PCR amplification. Nine ESTS correspond to 8 known human genes and 6 others show similarities with vertebrate genes, whereas the remaining 49 ESTS markers correspond to novel genes with no database similarities. These gene transcript markers will contribute to the developing physical and expression maps of chromosome 8, and to the search for candidate genes for various human diseases.
Ugolini
F
F
Laboratoire d'Oncologie Moléculaire, U.119 INSERM, Marseille, France.
Chaffanet
M
M
Houlgatte
R
R
Patterson
D
D
Wells
D
D
Auffray
C
C
Birnbaum
D
D
Pébusque
M J
MJ
D000818:Animals; D002874:Chromosome Mapping; D002898:Chromosomes, Human, Pair 8 / Q000235:genetics* / Q000648:ultrastructure; D006224:Cricetinae; D015870:Gene Expression; D005819:Genetic Markers; D006801:Humans; D006822:Hybrid Cells; D051379:Mice; D016133:Polymerase Chain Reaction; D051381:Rats; D014158:Transcription, Genetic
D005819:Genetic Markers