Drug-induced agranulocytosis.
Drug-induced agranulocytosis is a rare, potentially fatal idiosyncratic reaction that can occur unpredictably with a wide variety of drugs when taken in a conventional dose. In this article, we discuss its diagnosis and management and we consider the drugs most commonly involved and ways of minimising risk. We do not consider the dose-related granulocytopenia that commonly complicates treatment with cytotoxic and other myelosuppressant drugs, nor the rarer reaction, aplastic anaemia.
D000380:Agranulocytosis / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use; D006801:Humans; D009894:Opportunistic Infections / Q000188:drug therapy; D011994:Recombinant Proteins
D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor