title: [Use of ofloxacin in the treatment of suppurative-inflammatory complications in surgery].
abstract: Analysis of ofloxacin use in clinical surgery over the latest decade showed that despite its wide clinical application for the prevention and therapy of postoperative complications, this drug remains highly active for the majority of micro-organisms. Hence, a wide spectrum, high bactericidal activity of the drug, optimal pharmacokinetics, and a high bio-availability (95-100%) still recommend ofloxacin, a highly effective agent for the treatment of infectious complications of surgery.
authors.forename: N S
authors.initials: NS
authors.lastname: Bogomolova
authors.forename: L V
authors.initials: LV
authors.lastname: Bol'shakov
authors.forename: L N
authors.initials: LN
authors.lastname: Vinogradova
authors.forename: V I
authors.initials: VI
authors.lastname: Sorokina
authors.forename: T D
authors.initials: TD
authors.lastname: Oreshkina
authors.forename: E S
authors.initials: ES
authors.lastname: Tret'iakova
mesh_terms: D000150:Acinetobacter / Q000187:drug effects; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D004755:Enterobacteriaceae / Q000187:drug effects; D006801:Humans; D007249:Inflammation / Q000188:drug therapy*; D008826:Microbial Sensitivity Tests; D015242:Ofloxacin / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000188:drug therapy*; D011549:Pseudomonas / Q000187:drug effects; D013210:Staphylococcus / Q000187:drug effects; D013492:Suppuration / Q000188:drug therapy
chemical_list: D000890:Anti-Infective Agents; D015242:Ofloxacin