Intrarenal localization of nitric oxide synthase isoforms and soluble guanylyl cyclase.
1. Nitric oxide (NO) plays an important role in the regulation of renal function. To date, five isoforms of NO synthase (NOS) and four subunits of soluble guanylyl cyclase have been cloned. The kidney contains four isoforms of NOS and all subunits of soluble guanylyl cyclase. 2. This review focuses on the intrarenal location of the isoforms of NOS and the subunits of soluble guanylyl cyclase.
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UT-Southwestern Medical Center, Dallas 75235-8856, USA. rstar@mednet.swmed.edu
D000818:Animals; D006162:Guanylate Cyclase / Q000378:metabolism*; D007668:Kidney / Q000378:metabolism*; D019001:Nitric Oxide Synthase / Q000378:metabolism*; D013237:Stereoisomerism
D019001:Nitric Oxide Synthase; D006162:Guanylate Cyclase