title: Ophthalmomyiasis interna posterior and pigmentary retinopathy of Guam.
abstract: BACKGROUND
  Ophthalmomyiasis is ocular invasion by a fly larva. In the United States, only two cases of bilateral subretinal ophthalmomyiasis have been reported in the literature. Subretinal invasion by the fly larva results in characteristic ophthalmoscopic and angiographic findings. Recently, similar subretinal changes have been associated with amyotrophic lateral sclerosis/Parkinsonism dementia complex (ALS-PDC) in the Chamorro population of Guam. This pigmentary retinopathy of Guam (PROG) is generally bilateral in presentation, whereas ophthalmomyiasis is generally unilateral. While PROG has been associated with neurologic findings, ophthalmomyiasis interna posterior (OIP) has not.
  
  
  METHODS
  A case of a 65-year-old Asian man with bilateral subretinal changes is described. Similarities and differences between ophthalmomyiasis and the pigmentary retinopathy of Guam are discussed.
  
  
  CONCLUSIONS
  Because PROG has been associated with ALS-PDC, a neurologic evaluation should be included in the workup of patients suspected of having OIP or PROG.
authors.affiliation: DVA West Side Medical Center, Chicago, Illinois 60680, USA.
authors.forename: N K
authors.initials: NK
authors.lastname: Hira
authors.forename: M M
authors.initials: MM
authors.lastname: Marciniak
authors.forename: S L
authors.initials: SL
authors.lastname: Penner
mesh_terms: D000368:Aged; D000818:Animals; D003937:Diagnosis, Differential; D004175:Diptera; D015822:Eye Infections, Parasitic / Q000209:etiology* / Q000473:pathology; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006141:Guam; D006801:Humans; D007814:Larva; D008297:Male; D009198:Myiasis / Q000209:etiology* / Q000473:pathology; D012160:Retina / Q000469:parasitology / Q000473:pathology*; D012174:Retinitis Pigmentosa / Q000469:parasitology* / Q000473:pathology; D012189:Retrospective Studies