title: Effectiveness of atorvastatin for reducing low-density lipoprotein cholesterol to National Cholesterol Education Program treatment goals.
abstract: Atorvastatin is a highly efficacious hydroxymethylglutaryl-coenzyme A reductase inhibitor that has been shown to reduce low-density lipoprotein cholesterol by 40% to 60%. Monotherapy with atorvastatin (10 to 80 mg/day) is well-tolerated, convenient, and appears to be effective for achieving National Cholesterol Education Program treatment goals in most patients, regardless of risk status.
authors.affiliation: Chicago Center for Clinical Research, Illinois 60610, USA.
authors.forename: M H
authors.initials: MH
authors.lastname: Davidson
authors.forename: J W
authors.initials: JW
authors.lastname: Nawrocki
authors.forename: S R
authors.initials: SR
authors.lastname: Weiss
authors.forename: S L
authors.initials: SL
authors.lastname: Schwartz
authors.forename: P J
authors.initials: PJ
authors.lastname: Lupien
authors.forename: P H
authors.initials: PH
authors.lastname: Jones
authors.forename: H E
authors.initials: HE
authors.lastname: Haber
authors.forename: D M
authors.initials: DM
authors.lastname: Black
mesh_terms: D000924:Anticholesteremic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D000069059:Atorvastatin; D008078:Cholesterol, LDL / Q000097:blood*; D006538:Heptanoic Acids / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011758:Pyrroles / Q000008:administration & dosage / Q000627:therapeutic use*; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000924:Anticholesteremic Agents; D008078:Cholesterol, LDL; D006538:Heptanoic Acids; D011758:Pyrroles; D000069059:Atorvastatin