[Chronic inflammation of mucous membranes: integration of immunity and regeneration].
Lymphoid tissue of mucous membranes is a morphological basis for local immunity. Lymphocytes of mucous membranes are bifunctional: reception of antigenic information and regulation of epithelial cells regeneration. The following structural manifestations of intercellular interactions are discussed: expression of HLA-DR antigens by the epithelium and endotheliocytes transforming them into "facultative" antigen-presenting cells; polyclonal plasmocyte proliferation; the exchange of their prevailing IgA phenotype for IgG; cytotoxic and cytogenetic effect of the interepithelial lymphocytes.
Zinov'ev
A S
AS
Kononov
A V
AV
D001980:Bronchi / Q000473:pathology; D002908:Chronic Disease; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D018928:Immunity, Mucosal; D007136:Immunoglobulins / Q000276:immunology; D007249:Inflammation / Q000276:immunology* / Q000473:pathology / Q000503:physiopathology; D007413:Intestinal Mucosa / Q000473:pathology; D012038:Regeneration / Q000502:physiology*
D007136:Immunoglobulins