Recurrent brief depression in Prader-Willi syndrome: a case report.
Prader-Willi syndrome is caused by a deletion of 15q11-13 or maternal disomy of chromosome 15. A female patient with Prader-Willi syndrome, who was 19 years of age at the first onset of her recurrent brief episodes, is described. The episodes showed a near-monthly rhythm and were followed by a spontaneous remission in 7-18 days. The symptoms during the episodes were anorexia, insomnia, guilt feelings, ideas of being doomed, ostracized and persecuted, and stupor alternating with agitation.
Watanabe
H
H
Department of Psychiatry, University of Occupational and Environmental Health, Kitakyushu, Japan.
Ohmori
O
O
Abe
K
K
D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use; D002872:Chromosome Deletion; D002884:Chromosomes, Human, Pair 15 / Q000235:genetics; D003866:Depressive Disorder / Q000150:complications* / Q000188:drug therapy / Q000235:genetics; D005260:Female; D006801:Humans; D008094:Lithium / Q000627:therapeutic use; D011218:Prader-Willi Syndrome / Q000150:complications / Q000235:genetics / Q000523:psychology*; D012008:Recurrence
D000928:Antidepressive Agents; D008094:Lithium