title: Acute hemorrhagic conjunctivitis outbreak in Thailand, 1992.
abstract: The 260 cases of acute hemorrhagic conjunctivitis seen at Siriraj Hospital during October to December, 1992 were studied. Evidence of coxsackie virus A24 variant (CA24v) infections was demonstrated in 76.8% of 95 cases. The isolation rates from conjunctival swabs and throat swabs were 68.2% and 32.8%, respectively. A four-fold rising titer of neutralizing antibody was shown in 59.5% of 42 cases. The disease was characterized by a short incubation period, sudden onset, a mild and self-limited course within 5 days without ocular sequelae. Lacrimation, swelling lida, itching, foreign body sensation and periorbital pain were common features with bilateral involvement in the majority of cases. Approximately 48% of eyes had a mucopurulent discharge. Preauricular lymphadenopathy, keratitis and subconjunctival hemorrhage were observed in 16.2%, 12.6%, and 10.1% of affected eyes, respectively. Respiratory disturbances accompanied the eye signs in some cases. Only one case developed neurological complications: facial palsy was observed for three months without recovery.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: P
authors.initials: P
authors.lastname: Kosrirukvongs
authors.forename: R
authors.initials: R
authors.lastname: Kanyok
authors.forename: S
authors.initials: S
authors.lastname: Sitritantikorn
authors.forename: C
authors.initials: C
authors.lastname: Wasi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003232:Conjunctivitis, Acute Hemorrhagic / Q000150:complications / Q000453:epidemiology* / Q000821:virology*; D003384:Coxsackievirus Infections / Q000150:complications / Q000453:epidemiology* / Q000821:virology*; D004196:Disease Outbreaks; D004770:Enterovirus; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009500:Neutralization Tests; D011159:Population Surveillance; D011446:Prospective Studies; D013785:Thailand / Q000453:epidemiology