Scedosporium prolificans corneoscleritis: a successful outcome.
BACKGROUND
A case of Scedosporium prolificans corneoscleritis is reported in a patient who had developed scleral necrosis following pterygium surgery, with adjunctive beta-irradiation. This fungus has been reported to be the causative organism in only two previous cases of corneoscleritis.


METHODS
The patient presented with signs and symptoms typical of corneoscleritis. When the fungus was isolated from a biopsy specimen, aggressive scleral debridement was carried out and intensive antifungal therapy was instigated.


RESULTS
After a prolonged course, the eye was rendered sterile.


CONCLUSIONS
Early conjunctival recession and aggressive scleral debridement combined with intensive instillation of antifungals are crucial to the successful management of fungal corneoscleritis.
Kumar
B
B
Department of Ophthalmology, Royal Perth Hospital, Australia.
Crawford
G J
GJ
Morlet
G C
GC
D000935:Antifungal Agents / Q000627:therapeutic use; D001706:Biopsy; D003315:Cornea / Q000382:microbiology / Q000473:pathology; D003646:Debridement; D015821:Eye Infections, Fungal / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D006801:Humans; D007634:Keratitis / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D003904:Mitosporic Fungi / Q000302:isolation & purification; D009181:Mycoses / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D009336:Necrosis; D011625:Pterygium / Q000532:radiotherapy / Q000601:surgery; D012590:Sclera / Q000382:microbiology / Q000473:pathology; D015423:Scleritis / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology
D000935:Antifungal Agents