title: Postoperative acute pulmonary edema: a rare presentation of pheochromocytoma.
abstract: A 39-year-old white female underwent an uneventful vaginal hysterectomy for dysfunctional bleeding. Evaluating a mild aortic insufficiency murmur preoperatively an echocardiogram revealed normal left ventricular wall motion and function. Postoperatively the patient developed severe abdominal pain, acute hypertension (200/100 mmHg), and sinus tachycardia. Within minutes she decompensated into acute pulmonary edema. ECG demonstrated acute ST segment elevation in the precordial leads consistent with acute infarction. Emergency left heart catheterization showed normal coronary vessels with severe left ventricular dysfunction. An abdominal ultrasound was obtained, revealing a right adrenal mass. Plasma epinephrine was 334, norepinephrine 34,543 pg/ml; urine epinephrine 45, urine norepinephrine 2,137 micrograms/24 hours. She was started on prazosin and nifedipine sustained release with good blood pressure control. Four days later, an echocardiogram demonstrated the left ventricular wall motion reverting to normal. The adrenal tumor was subsequently resected successfully. Acute pulmonary edema causing dilated cardiomyopathy is a rare complication of pheochromocytoma that has been seldomly reported. A progressive fatal course is common: reversibility and survival depend on identifying and removing the pheochromocytoma.
authors.affiliation: Medical College of Virginia, Department of Medicine, MCV Station, Richmond, USA.
authors.forename: N
authors.initials: N
authors.lastname: Fahmy
authors.forename: M
authors.initials: M
authors.lastname: Assaad
authors.forename: P
authors.initials: P
authors.lastname: Bathija
authors.forename: F C
authors.initials: FC
authors.lastname: Whittier
mesh_terms: D000208:Acute Disease; D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D000328:Adult; D001794:Blood Pressure; D002311:Cardiomyopathy, Dilated / Q000150:complications / Q000175:diagnosis; D005260:Female; D006801:Humans; D007045:Hysterectomy, Vaginal / Q000009:adverse effects*; D010673:Pheochromocytoma / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D011183:Postoperative Complications; D011654:Pulmonary Edema / Q000209:etiology*; D014592:Uterine Hemorrhage / Q000601:surgery