Mutans streptococcal serotypes in children with gastroesophageal reflux disease.
It has been suggested that vomiting acid gastric contents in bulimia might favor oral growth of Streptococcus sobrinus. We studied the colonization of Streptococcus sobrinus (serotypes g and d) and Streptococcus mutans (serotypes c, e and f) in sixteen children, ages five to fifteen years, who had suffered for four to eleven years from gastroesophageal reflux, another condition with recurrent acid regurgitation. Our aim was to find out if the prevalence of Streptococcus sobrinus would be higher also in this patient group. Mutants streptococci were detected in twelve out of sixteen (75 percent) study patients of the saliva samples cultured on MSB agar. For the Mutans streptococci positive children healthy controls were matched by salivary levels of mutans streptococci and age as closely as possible. From each child three to six isolates representing both Streptococcus mutans and Streptococcus sobrinus (n = 103) were serotyped by immunodiffusion method. The distribution of serotypes in the study/control group was: c: 7/10; e: 4/2; f: 0/1; g:3/2; d:0/0. One strain in the study group remained untypable. All patients infected with Streptococcus sobrinus were also infected with Streptococcus mutans. Our results indicate the great similarity in the distribution of ms serotypes in the gastroesophageal reflux children and their healthy controls. The data do not suggest that the acid regurgitation would have an influence on the prevalence of Streptococcus sobrinus.
Hölttä
P
P
Department of Pedodontics and Orthodontics, University of Helsinki, Finland.
Aine
L
L
Mäki
M
M
Ruuska
T
T
Vuento
R
R
Ashorn
M
M
Alaluusua
S
S
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005764:Gastroesophageal Reflux / Q000382:microbiology*; D006801:Humans; D012463:Saliva / Q000382:microbiology; D012703:Serotyping / Q000706:statistics & numerical data; D018709:Statistics, Nonparametric; D013295:Streptococcus mutans / Q000145:classification* / Q000302:isolation & purification; D016986:Streptococcus sobrinus / Q000145:classification / Q000302:isolation & purification