title: Sclerosing cholangitis associated with hypereosinophilic syndrome.
abstract: A 15-year-old male with hypereosinophilic syndrome was admitted to our hospital because of general malaise and abnormal liver function tests. Endoscopic retrograde cholangiopancreatography demonstrated bile duct changes consistent with primary sclerosing cholangitis. The patient's liver profile tests returned to normal after treatment with prednisolone and ursodeoxycholic acid. In this case, eosinophils might have played an important role in the pathogenesis of the bile duct lesion.
authors.affiliation: Department of Rheumatology, Institute of Rheumatology, Tokyo Women's Medical College.
authors.forename: N
authors.initials: N
authors.lastname: Ichikawa
authors.forename: A
authors.initials: A
authors.lastname: Taniguchi
authors.forename: H
authors.initials: H
authors.lastname: Akama
authors.forename: H
authors.initials: H
authors.lastname: Ishiguro
authors.forename: T
authors.initials: T
authors.lastname: Kurihara
authors.forename: C
authors.initials: C
authors.lastname: Terai
authors.forename: M
authors.initials: M
authors.lastname: Hara
authors.forename: S
authors.initials: S
authors.lastname: Kashiwazaki
mesh_terms: D000293:Adolescent; D015209:Cholangitis, Sclerosing / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D014580:Ursodeoxycholic Acid / Q000627:therapeutic use
chemical_list: D014580:Ursodeoxycholic Acid; D011241:Prednisone