title: [Panorama of uropathies discovered during the prenatal period. 147 cases].
abstract: OBJECTIVE
  The aim of this study was to establish the panorama of uropathies discovered during the antenatal period and to analyze the explorations performed. Pregnancy outcome and infant prognosis was also recorded.
  
  
  METHODS
  Ultrasonographic imaging revealed dilatation in 62.5% of the cases, parenchymal anomalies in 26.3% and unilateral or bilateral agenesia in 11.2%. The percentage of abnormal karyotypes was 4.76% for all urorenal symptomatologies. These abnormal karyotypes corresponded to 10% of those performed in 17 fetuses, urine puncture was used in order to assess in utero renal function. There were 113 live births, 31 medically termined pregnancies and 3 spontaneous abortions. Among the 113 live infants, 12 died during the post-natal period. Thirty-two infants were considered to be normal and 69 had an urorenal malformation, including 2 infants with pre-end-stage renal failure at 4 and 3 years.
  
  
  CONCLUSIONS
  It is uncommon to discover an urorenal malformation at prenatal ultrasonography. The main problem is antenatal management and evaluation of prognosis. Urine puncture and in utero derivation are discussed. When no other reliable factors affecting fetal prognosis are available, puncture of fetal urine provides useful information for management although the technique remains under debate.
authors.affiliation: Service de Gynécologie-Obstétrique, Hôpital Jeanne de Flandre, Lille.
authors.forename: S
authors.initials: S
authors.lastname: Vanderstichele
authors.forename: P
authors.initials: P
authors.lastname: Dufour
authors.forename: C
authors.initials: C
authors.lastname: Lefebvre
authors.forename: A S
authors.initials: AS
authors.lastname: Valat
authors.forename: F
authors.initials: F
authors.lastname: Puech
authors.forename: X
authors.initials: X
authors.lastname: Codaccioni
authors.forename: J C
authors.initials: JC
authors.lastname: Monnier
mesh_terms: D000032:Abortion, Therapeutic; D000013:Congenital Abnormalities / Q000000981:diagnostic imaging / Q000235:genetics / Q000652:urine; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D011247:Pregnancy; D011256:Pregnancy Outcome; D011379:Prognosis; D012189:Retrospective Studies; D016216:Ultrasonography, Prenatal; D014551:Urinary Tract / Q000002:abnormalities*