title: Valproate inhibits the mitochondrial pyruvate-driven oxidative phosphorylation in vitro.
authors.affiliation: C.M.G., Faculdade de Farmácia, Universidade de Lisboa, Portugal.
authors.forename: M F
authors.initials: MF
authors.lastname: Silva
authors.forename: J P
authors.initials: JP
authors.lastname: Ruiter
authors.forename: L
authors.initials: L
authors.lastname: Illst
authors.forename: C
authors.initials: C
authors.lastname: Jakobs
authors.forename: M
authors.initials: M
authors.lastname: Duran
authors.forename: I T
authors.initials: IT
authors.lastname: de Almeida
authors.forename: R J
authors.initials: RJ
authors.lastname: Wanders
mesh_terms: D000255:Adenosine Triphosphate / Q000096:biosynthesis; D000818:Animals; D000927:Anticonvulsants / Q000494:pharmacology*; D004072:Digitonin / Q000494:pharmacology; D066298:In Vitro Techniques; D008297:Male; D008930:Mitochondria, Liver / Q000187:drug effects / Q000378:metabolism*; D010085:Oxidative Phosphorylation / Q000187:drug effects*; D010101:Oxygen Consumption / Q000187:drug effects; D011048:Polarography; D011773:Pyruvates / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D014635:Valproic Acid / Q000494:pharmacology*
chemical_list: D000927:Anticonvulsants; D011773:Pyruvates; D014635:Valproic Acid; D000255:Adenosine Triphosphate; D004072:Digitonin