title: Timing of the occurrence of pulmonary embolism in trauma patients.
abstract: OBJECTIVE
  To determine how soon after trauma pulmonary embolism (PE) occurs and if there is an association between the duration of this interval and mortality.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  All patients admitted to our trauma service with established PE based on high probability findings on ventilation perfusion scan, positive results on a pulmonary arteriogram, or autopsy from July 1, 1990, to September 30, 1995.
  
  
  METHODS
  Time interval between injury and PE.
  
  
  METHODS
  Level I university trauma center.
  
  
  RESULTS
  Of 18,255 trauma patients identified, 63 met our criteria for PE (30 using a pulmonary arteriogram; 26, a ventilation perfusion scan; and 7, autopsy). Four patients (6%) had a documented PE on day 1 following injury. Mortality was not correlated with the interval between injury and PE. Of the 63 patients, 58 (92%) had 1 or more established risk factors for thromboembolism. The ratio of PaO2 to fraction of inspired oxygen was the only factor predictive of mortality (P = .02, logistic regression analysis).
  
  
  CONCLUSIONS
  Pulmonary embolism occurs in the immediate period following injury. Aggressive workup in patients with signs consistent with PE should be instituted promptly. Trauma patients who have at least 1 risk factor for thromboembolism should receive prophylaxis as soon after injury as possible.
authors.affiliation: Department of Surgery, University of California, Davis, Medical Center, Sacramento, USA.
authors.forename: J T
authors.initials: JT
authors.lastname: Owings
authors.forename: E
authors.initials: E
authors.lastname: Kraut
authors.forename: F
authors.initials: F
authors.lastname: Battistella
authors.forename: J T
authors.initials: JT
authors.lastname: Cornelius
authors.forename: R
authors.initials: R
authors.lastname: O'Malley
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology / Q000628:therapy; D012189:Retrospective Studies; D013997:Time Factors; D014947:Wounds and Injuries / Q000150:complications*