title: Audiogenic startle reflex in acute hemiplegia.
abstract: The generators of the audiogenic startle reflex (ASR) are located in the bulbopontine reticular formation. We studied the influence of acute vascular supratentorial lesions on ASR. Ten patients with hemiplegia due to hemispheric cerebral infarct were studied within 5 days of stroke onset. ASR and magnetic cortical stimulation were performed the same day. A muscle response to magnetic stimulation was not elicited over the plegic side in any patient. In four of seven patients, ASR was enhanced over the plegic side. We suggest that enhanced ASR is due to the loss of a predominantly inhibitory hemispheric drive on ASR generators.
authors.affiliation: Service de Neurologie, Hôpital Erasme, Université Libre de Bruxelles, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Voordecker
authors.forename: N
authors.initials: N
authors.lastname: Mavroudakis
authors.forename: S
authors.initials: S
authors.lastname: Blecic
authors.forename: J
authors.initials: J
authors.lastname: Hildebrand
authors.forename: D
authors.initials: D
authors.lastname: Zegers de Beyl
mesh_terms: D000161:Acoustic Stimulation; D000208:Acute Disease; D000328:Adult; D000368:Aged; D001132:Arm; D002544:Cerebral Infarction / Q000150:complications*; D019054:Evoked Potentials, Motor; D005260:Female; D006429:Hemiplegia / Q000209:etiology* / Q000503:physiopathology*; D006801:Humans; D008280:Magnetics; D008297:Male; D008875:Middle Aged; D009132:Muscles / Q000503:physiopathology; D010812:Physical Stimulation; D011930:Reaction Time; D013216:Reflex, Startle / Q000502:physiology*