title: Glottic-supraglottic barrier: fact or fantasy?
abstract: An anatomic structure that might act as a barrier between the glottic and supraglottic areas has never been demonstrated in whole organ serial section studies. Nevertheless, most squamous cell carcinomas arising on the supraglottic mucosa remain confined above the ventricle, and this fact is reflected in the high rate of local control obtained by surgeons performing horizontal supraglottic laryngectomy: 80.6% to 98%. Whole organ sections of laryngectomy specimens suggest that a tumor situated above and below the glottic level may have arrived there not by crossing the ventricle, but by encircling it. In so doing, part of the tumor is visible posterior to the ventricle or on the arytenoid cartilage-a finding that contraindicates conventional supraglottic laryngectomy, with or without limited mobility of the true vocal cord.
authors.affiliation: Dept of Surgery, Yale University School of Medicine, New Haven, Connecticut 06520-8041, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Kirchner
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery; D005931:Glottis / Q000473:pathology*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology* / Q000601:surgery; D007825:Laryngectomy; D007830:Larynx / Q000473:pathology; D009361:Neoplasm Invasiveness