Actinomycotic splenic abscesses presenting with arthritis.
An 18-month-old Caucasian female began with a high fever. She developed swelling in one finger and one toe. Abdominal ultrasound revealed multiple abscesses in her spleen. Multiple blood culture and splenic abscess aspirations grew no pathogens. She had transient response to multiple antibiotics and splenic abscess drainage, but fever returned along with subcutaneous nodules. Culture of splenic tissue from her second splenic drainage eventually grew one organism identified as Actinomyces naeslundii. Therapy with high dose penicillin followed by amoxicillin p.o. and total splenectomy led to complete recovery.
Quintero-Del-Rio
A I
AI
Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas 75235-9063, USA.
Trujillo
M
M
Fink
C W
CW
D000038:Abscess / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D000190:Actinomyces / Q000302:isolation & purification*; D000196:Actinomycosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016918:Arthritis, Reactive / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007223:Infant; D010400:Penicillin G / Q000627:therapeutic use; D010406:Penicillins / Q000627:therapeutic use; D013154:Spleen / Q000000981:diagnostic imaging / Q000382:microbiology; D013158:Splenic Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D014057:Tomography, X-Ray Computed; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D010406:Penicillins; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D010400:Penicillin G