title: MRI screening for acoustic neuroma without gadolinium: value of 3DFT-CISS sequence.
abstract: To evaluate the efficacy of a gradient-echo sequence (3DFT-CISS) in the diagnosis of acoustic neuromas, two independent observers twice reviewed the images of the temporal bones of 83 patients. Contrast-enhanced T1-weighted spin echo images were used as the reference, showing 18 acoustic neuromas, including 5 purely intracanalicular and one intralabyrinthine tumours. High sensitivity (89-94%), specificity (94-97%) and accuracy (94-95%) were found. Intraobserver (kappa 0.93-1) and interobserver (kappa 0.83-0.84) reproducibility were very good. The smallest intracanalicular tumour was overlooked twice by both observers; the intralabyrinthine tumour once by one observer. All tumours were detected with a less stringent decision criterion, at the expense of lower specificity.
authors.affiliation: Department of Radiology, University Hospital K.U. Leuven, Belgium.
authors.forename: R
authors.initials: R
authors.lastname: Hermans
authors.forename: A
authors.initials: A
authors.lastname: Van der Goten
authors.forename: B
authors.initials: B
authors.lastname: De Foer
authors.forename: A L
authors.initials: AL
authors.lastname: Baert
mesh_terms: D016477:Artifacts; D003362:Cost-Benefit Analysis; D003937:Diagnosis, Differential; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000191:economics; D008403:Mass Screening / Q000191:economics; D009464:Neuroma, Acoustic / Q000175:diagnosis / Q000453:epidemiology*; D015588:Observer Variation; D012372:ROC Curve; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013701:Temporal Bone / Q000473:pathology