The cytochrome oxidase subunit 1 gene (cox1) from the dinoflagellate, Crypthecodinium cohnii.
To date, no genes have been characterized from dinoflagellate mitochondrial DNA. Here we present the complete sequence of the gene (cox1) encoding subunit 1 of cytochrome c oxidase in the dinoflagellate, Crypthecodinium cohnii. Analysis of nucleotide and deduced amino acid sequences predicts a protein of 523 amino acids that is translated using universal initiation, stop and tryptophan codons. COX1 amino acid identity and phylogenetic tree analyses strongly support a close evolutionary relationship between dinoflagellates and apicomplexans; however, inclusion of the ciliates in this clade is less well supported, a result likely due to the highly derived nature of ciliate COX1 sequences.
Norman
J E
JE
Program in Evolutionary Biology, Canadian Institute for Advanced Research, Department of Biochemistry, Dalhousie University, Halifax, Nova Scotia.
Gray
M W
MW
D000595:Amino Acid Sequence; D000818:Animals; D003001:Cloning, Molecular; D003062:Codon / Q000235:genetics; D004272:DNA, Mitochondrial / Q000235:genetics*; D016054:DNA, Protozoan / Q000235:genetics; D004141:Dinoflagellida / Q000235:genetics*; D003576:Electron Transport Complex IV / Q000235:genetics*; D017125:Genes, Protozoan / Q000235:genetics*; D008969:Molecular Sequence Data; D016366:Open Reading Frames / Q000235:genetics; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid; D014364:Tryptophan / Q000235:genetics
D003062:Codon; D004272:DNA, Mitochondrial; D016054:DNA, Protozoan; D014364:Tryptophan; D003576:Electron Transport Complex IV