Molecular biology of iron and zinc uptake in eukaryotes.
Recent studies of iron uptake in Saccharomyces cerevisiae have provided insights into the role of multicopper oxidases in eukaryotic metal transport. These studies have also led to the identification of a novel iron transporter in plants and the recognition of a new family of transporter proteins that may participate in metal uptake in a diverse array of eukaryotic species.
Eide
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Nutritional Sciences Program, University of Missouri-Columbia 65211, USA. deide@showme.missouri.edu
D000818:Animals; D001692:Biological Transport; D002352:Carrier Proteins / Q000235:genetics / Q000378:metabolism*; D002462:Cell Membrane / Q000378:metabolism; D002570:Ceruloplasmin; D005057:Eukaryotic Cells / Q000378:metabolism; D006801:Humans; D007501:Iron / Q000378:metabolism*; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism*; D008954:Models, Biological; D005810:Multigene Family; D010088:Oxidoreductases / Q000235:genetics / Q000378:metabolism; D010802:Phylogeny; D010944:Plants / Q000378:metabolism; D012441:Saccharomyces cerevisiae / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins; D015032:Zinc / Q000378:metabolism*
D002352:Carrier Proteins; D008565:Membrane Proteins; D029701:Saccharomyces cerevisiae Proteins; D007501:Iron; D010088:Oxidoreductases; D002570:Ceruloplasmin; C085513:FET3 protein, S cerevisiae; D015032:Zinc