title: Nasal hypersensitivity and recurrent adenoids disease.
abstract: Authors studied nasal hypersensitivity (NH) behaviour on 41 subjects suffering from recurrent adenoids disease during their paediatric age. All subjects underwent clinical history, ENT examination, skin-test, RAST and non-specific nasal provocation test with histamine and assessment of the amount of sneezes. The results showed a familial transmission of the NH in 53.6% of cases, a hypogammaglobulinemia in 14.6% of cases. NH was present in 57% of subjects, much more with higher number of phlogosis, with higher possibility of familial transmission and with premature socialisation. These data showed a strict correlation between NH and recurrent adenoids disease. This NH didn't reduce in subjects undergone adenoidectomy and with time it conditioned the answer of the whole airways which could be noticed also in adulthood subjects. The presence of this NH had remarkable significance for diagnosis and therapeutic behaviour.
authors.affiliation: ENT Department, University of Rome La Sapienza, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Filiaci
authors.forename: G
authors.initials: G
authors.lastname: Zambetti
authors.forename: A
authors.initials: A
authors.lastname: Lovecchio
authors.forename: R
authors.initials: R
authors.lastname: Romeo
mesh_terms: D000233:Adenoidectomy; D000234:Adenoids / Q000473:pathology / Q000601:surgery*; D002648:Child; D002656:Child Day Care Centers; D002675:Child, Preschool; D004198:Disease Susceptibility; D005260:Female; D006632:Histamine / Q000494:pharmacology; D006801:Humans; D006984:Hypertrophy; D017098:IgA Deficiency / Q000150:complications; D017099:IgG Deficiency / Q000150:complications; D015994:Incidence; D008297:Male; D009299:Nasal Provocation Tests; D009668:Nose Diseases / Q000150:complications* / Q000175:diagnosis; D011183:Postoperative Complications / Q000453:epidemiology; D011852:Radioallergosorbent Test; D012008:Recurrence; D012130:Respiratory Hypersensitivity / Q000150:complications* / Q000175:diagnosis; D012141:Respiratory Tract Infections / Q000453:epidemiology; D012882:Skin Tests; D012912:Sneezing / Q000187:drug effects*
chemical_list: D006632:Histamine