title: Adrenal carcinosarcoma--a case report.
abstract: Carcinosarcoma of the adrenal gland is an extremely rare variant of adrenocortical carcinoma, characterized by a biphasic pattern of carcinoma and sarcoma-like components. We report a case of adrenal carcinosarcoma occurring in a 61-year-old Korean man who presented with right flank pain of one month duration radiating to the back and right iliac crest. The tumor measured 12 x 12 x 7 cm and adhered to the liver and right upper pole of the kidney. The carcinomatous component of the tumor showed polygonal cells in a broad anastomosing trabecular pattern with delicate slit-like vascular channels; the sarcomatous component showed uniform spindled cells in a fascicular pattern. Both the carcinomatous and sarcomatous portions of the tumor were positive for pan-cytokeratin, and vimentin stained only the sarcomatous areas.
authors.affiliation: Department of Pathology and Urology, Seoul National University College of Medicine, Korea.
authors.forename: M S
authors.initials: MS
authors.lastname: Lee
authors.forename: I A
authors.initials: IA
authors.lastname: Park
authors.forename: J G
authors.initials: JG
authors.lastname: Chi
authors.forename: E K
authors.initials: EK
authors.lastname: Ham
authors.forename: K C
authors.initials: KC
authors.lastname: Lee
authors.forename: C W
authors.initials: CW
authors.lastname: Lee
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000175:diagnosis*; D002296:Carcinosarcoma / Q000175:diagnosis*; D006801:Humans; D007723:Korea; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed