[Quantification of lamellar bodies in amniotic fluid: a method for the evaluation of fetal pulmonary maturity].
It was tried to know the counting up of lamellar bodies in amniotic fluid, as a test of fetal pulmonary maturity, comparing it with neonatal evolution. 31 samples of amniotic fluid of different ages of gestation, were obtained, lamellar bodies were quantified with a standard equipment of hematic counting, and comparing with neonatal evolution, sensitivity, specificity, positive predictive value, and negative predictive value are established. The established concentration of 30,000/l by comparison with Lecitine/Esfingomieline and with Fosfatidilglycerol was used. From 29 patients with counts greater than 30,000, none presented Respiratory Difficulty syndrome (SDR); and from two patients with lower counts, one presented SDR and one had normal neonatal evolution. Sensitivity was 96%; specificity was 100%; predictive positive value, 50%; and negative predictive value was 100%. Because of this, the test is so useful in practice. Its statistical values, its minimal cost; easiness to do, and equipment availability, justify this test as a first election.
Carrillo
J
J
Centro de Ginecología y Obstetricia de Monterrey SA.
García
E
E
Lozano
C
C
Galache
P
P
Lozano
J
J
González
H
H
D000653:Amniotic Fluid / Q000737:chemistry*; D005260:Female; D005325:Fetal Organ Maturity; D005865:Gestational Age; D006801:Humans; D008168:Lung / Q000196:embryology*; D015388:Organelles / Q000648:ultrastructure; D011237:Predictive Value of Tests; D011247:Pregnancy