[The changes in plasma nitric oxide level in normal pregnant women and pregnancy induced hypertension].
OBJECTIVE
To investigate the relationship between nitric oxide (NO) level and pregnancy induced hypertension (PIH).


METHODS
The plasma level of NO in 36 cases of normal pregnant women (normal pregnancy group), 23 cases of PIH (PIH group), and 16 cases of non-pregnant women (control group) were measured and compared using fluorophotometry.


RESULTS
The NO level of normal pregnancy group was significantly higher than that of control group (P < 0.01), particularly in the second trimester of pregnancy. The NO level of PIH was significantly lower than that of third trimester of normal pregnancy (P < 0.01), and it decreased as the disease became severe.


CONCLUSIONS
Decreased synthesizing and releasing of NO might play an important role in pathogenesis of PIH.
Jin
Z
Z
Second Teaching Hospital, Bethune University of Medical Sciences, Changchun.
Wang
J
J
Li
S
S
D000328:Adult; D005260:Female; D006801:Humans; D009569:Nitric Oxide / Q000097:blood*; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy / Q000097:blood*
D009569:Nitric Oxide