Coenzyme Q homologs and vitamin E in synaptic and non-synaptic occipital cerebral cortex mitochondria in the ageing rat.
The coenzyme Q8 (CoQ8) and alpha-tocopherol contents of different mitochondrial fractions were investigated from occipital cerebral cortices of different ages. The highest CoQ8 and vitamin E concentrations were found in non-synaptic free mitochondria (FM) fractions. In several cases heavy mitochondria (HM) fractions displayed the lowest values. Occipital cerebral cortex mitochondria contained higher CoQ9 and lower CoQ10 amounts than those typical for other brain regions.
Battino
M
M
Institute of Biochemistry, Medical School, University of Ancona, Italy.
Svegliati Baroni
S
S
Littarru
G P
GP
Bompadre
S
S
Leone
L
L
Gorini
A
A
Villa
R F
RF
D000375:Aging / Q000378:metabolism*; D000818:Animals; D003067:Coenzymes; D008297:Male; D008928:Mitochondria / Q000737:chemistry*; D009778:Occipital Lobe / Q000737:chemistry* / Q000648:ultrastructure; D018384:Oxidative Stress; D051381:Rats; D017207:Rats, Sprague-Dawley; D013569:Synapses / Q000737:chemistry*; D014451:Ubiquinone / Q000031:analogs & derivatives* / Q000032:analysis*; D014810:Vitamin E / Q000032:analysis*
D003067:Coenzymes; D014451:Ubiquinone; D014810:Vitamin E; C030778:ubiquinone 8; C024989:coenzyme Q10