title: Physician-diagnosed asthma and drug utilization in the European Community Respiratory Health Survey.
abstract: The aim of this analysis was to estimate the geographical variation in the prevalence of physician-diagnosed asthma and treatment practice for asthma in young adults. The results are based on an ecological analysis of 34 centres in 14 countries, in which a total of 17,029 randomly selected subjects (52% females, age 20-48 yrs) underwent a structured interview and spirometry as part of the European Community Respiratory Health Survey. The sample was enriched with 2,903 symptomatic subjects when investigating treatment in subjects with physician-diagnosed asthma. The prevalence of physician-diagnosed asthma was highest in New Zealand and Australia (11-13%) and lowest in Erfurt, Germany (1.2%) and Spain (1.5-3.0%). The reported use of antiasthma medication in the last 12 months was also highest in New Zealand and Australia (12-16%) and correlated closely with the prevalence of diagnosed asthma (r=0.89, p<0.001). Herbal remedies against breathing problems had been used by 13% of subjects in Hamburg but the reported use of alternative remedies for breathing problems was low in most other centres. The use of inhaled anti-inflammatory drugs in subjects with physician-diagnosed asthma ranged from 49% in the UK to 17% in Italy and correlated with the prevalence of doctors' consultations within the last 12 months (r=0.66, p<0.05). The prevalence of anti-inflammatory treatment was positively related to the prevalence of nocturnal asthma symptoms (p<0.05). We conclude that there is a wide geographical variation in the prevalence of physician-diagnosed asthma and use of antiasthma medication. The geographical variation in the use of anti-inflammatory drugs among individuals with diagnosed asthma may be related to variations in asthma severity, as well as differences in treatment practices between countries.
authors.affiliation: Dept of Public Health Medicine, United Medical and Dental Schools of Guy's and St Thomas' Hospitals, London, UK.
authors.forename: C
authors.initials: C
authors.lastname: Janson
authors.forename: S
authors.initials: S
authors.lastname: Chinn
authors.forename: D
authors.initials: D
authors.lastname: Jarvis
authors.forename: P
authors.initials: P
authors.lastname: Burney
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology*; D001315:Australia; D001993:Bronchodilator Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D003154:Community Medicine; D000529:Complementary Therapies; D003710:Demography; D005060:Europe; D005260:Female; D006306:Health Surveys; D006801:Humans; D008297:Male; D008875:Middle Aged; D009520:New Zealand; D010820:Physicians; D015995:Prevalence; D012119:Respiration
chemical_list: D000893:Anti-Inflammatory Agents; D001993:Bronchodilator Agents