Primary pulmonary hypertension in a patient with CD8/T-cell large granulocyte leukemia: amelioration by cladribine therapy.
We report a case of primary pulmonary hypertension in an adult man with CD8/T-cell large granulocyte leukemia. Successful treatment of his leukemia with cladribine resulted in dramatic and sustained improvement of his pulmonary hypertension.
Rossoff
L J
LJ
Department of Medicine, Long Island Jewish Medical Center, New Hyde Park, NY 11042, USA.
Genovese
J
J
Coleman
M
M
Dantzker
D R
DR
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D018414:CD8-Positive T-Lymphocytes; D017338:Cladribine / Q000627:therapeutic use*; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology* / Q000517:prevention & control; D015461:Leukemia, Prolymphocytic, T-Cell / Q000150:complications* / Q000188:drug therapy*; D008297:Male
D000970:Antineoplastic Agents; D017338:Cladribine