title: Peptide growth factors and preimplantation development.
abstract: This paper examines some of the problems and questions that must be considered in relation to research on the role of growth factors in preimplantation embryos. It reviews and summarizes the large body of work on gene expression of growth factor receptors and ligands in preimplantation embryos and in oviduct and uterine tissue. It also reviews the literature on the effects of gene knockout in preimplantation embryos and concludes with a review of work on the effects of growth factors on cultured embryos.
authors.affiliation: Physiology Department, University College, Galway, Ireland. michael.kane@ucg.ie
authors.forename: M T
authors.initials: MT
authors.lastname: Kane
authors.forename: P M
authors.initials: PM
authors.lastname: Morgan
authors.forename: C
authors.initials: C
authors.lastname: Coonan
mesh_terms: D000818:Animals; D001755:Blastocyst / Q000502:physiology; D047108:Embryonic Development / Q000502:physiology*; D005314:Embryonic and Fetal Development; D005260:Female; D006133:Growth Substances / Q000502:physiology*; D051379:Mice; D010455:Peptides / Q000502:physiology*; D011247:Pregnancy
chemical_list: D006133:Growth Substances; D010455:Peptides