title: Novel bioreductive anticancer agents based on indolequinones.
abstract: The background to bioreductive drugs based on indolequinones is surveyed, and the development of novel cyclopropamitosenes as potent anticancer agents is reviewed. Thiazolylindoles were also investigated as potential inhibitors of topoisomerase II.
authors.affiliation: Department of Chemistry, University of Exeter, Devon, UK.
authors.forename: C J
authors.initials: CJ
authors.lastname: Moody
authors.forename: E
authors.initials: E
authors.lastname: Swann
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology; D011355:Prodrugs / Q000138:chemical synthesis; D011809:Quinones / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000970:Antineoplastic Agents; D007211:Indoles; D011355:Prodrugs; D011809:Quinones