Invasive versus non-invasive diagnosis of renal bone disease.
At present, bone histomorphometry remains the gold standard for the diagnosis of the various types of renal bone disease. In the search for a non-invasive method of diagnosis, biochemical serum markers of bone remodelling, in addition to serum intact parathyroid hormone and aluminium determinations, have been proposed as the most reliable tools and are at present widely used in clinical practice. Their respective diagnostic values, as separate items and in combined analysis, are thoroughly discussed in the present review.
Fournier
A
A
Department of Nephrology, Amiens-University Hospital, France. neph-chu@burotec.fr
Oprisiu
R
R
Said
S
S
Sechet
A
A
Ghazali
A
A
Marié
A
A
el Esper
I
I
Brazier
M
M
Achard
J M
JM
Morinière
P
P
D000535:Aluminum / Q000097:blood; D015415:Biomarkers / Q000097:blood; D001847:Bone Diseases / Q000097:blood / Q000150:complications* / Q000175:diagnosis*; D001851:Bone Diseases, Metabolic / Q000097:blood / Q000209:etiology; D016723:Bone Remodeling / Q000502:physiology; D002114:Calcinosis / Q000097:blood / Q000209:etiology; D005357:Fibrous Dysplasia of Bone / Q000175:diagnosis; D006801:Humans; D006934:Hypercalcemia / Q000097:blood / Q000209:etiology; D007674:Kidney Diseases / Q000097:blood / Q000150:complications* / Q000175:diagnosis*; D010018:Osteomalacia / Q000175:diagnosis; D010281:Parathyroid Hormone / Q000097:blood; D010710:Phosphates / Q000097:blood
D015415:Biomarkers; D010281:Parathyroid Hormone; D010710:Phosphates; D000535:Aluminum