B-complex vitamins in the prophylaxis and treatment of Wernicke-Korsakoff syndrome.
Wernicke-Korsakoff syndrome, which is associated with high morbidity and mortality, is a more common neuropsychiatric sequela of alcohol misuse than is widely realized. It is easily prevented and treated with parenteral B-complex vitamins, although this treatment is widely under-utilized.
Cook
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CC
Kent Institute of Medicine and Health Sciences, University of Kent, Canterbury.
Thomson
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AD
D000431:Ethanol / Q000009:adverse effects; D006801:Humans; D007263:Infusions, Parenteral; D007408:Intestinal Absorption; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy; D013832:Thiamine Deficiency / Q000188:drug therapy; D014803:Vitamin B Complex / Q000008:administration & dosage / Q000378:metabolism / Q000627:therapeutic use*; D014804:Vitamin B Deficiency / Q000188:drug therapy; D014899:Wernicke Encephalopathy / Q000188:drug therapy* / Q000517:prevention & control
D014803:Vitamin B Complex; D000431:Ethanol