title: 12,13-isotaxanes: synthesis of new potent analogs and X-ray crystallographic confirmation of structure.
authors.affiliation: Research Laboratories, Pharmacia & Upjohn, Inc., Kalamazoo, Michigan 49001, USA.
authors.forename: R A
authors.initials: RA
authors.lastname: Johnson
authors.forename: P J
authors.initials: PJ
authors.lastname: Dobrowolski
authors.forename: E G
authors.initials: EG
authors.lastname: Nidy
authors.forename: I
authors.initials: I
authors.lastname: Gebhard
authors.forename: S J
authors.initials: SJ
authors.lastname: Qualls
authors.forename: N A
authors.initials: NA
authors.lastname: Wicnienski
authors.forename: R C
authors.initials: RC
authors.lastname: Kelly
authors.forename: T W
authors.initials: TW
authors.lastname: Pitts
authors.forename: N M
authors.initials: NM
authors.lastname: Lopes
authors.forename: T F
authors.initials: TF
authors.lastname: DeKoning
authors.forename: S J
authors.initials: SJ
authors.lastname: Mattern
authors.forename: S D
authors.initials: SD
authors.lastname: Weed
authors.forename: J P
authors.initials: JP
authors.lastname: McGovren
authors.forename: C G
authors.initials: CG
authors.lastname: Chidester
mesh_terms: D000470:Alkaloids / Q000138:chemical synthesis / Q000737:chemistry / Q000633:toxicity; D000818:Animals; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D001952:Bridged-Ring Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D018360:Crystallography, X-Ray; D005260:Female; D006801:Humans; D008546:Melanoma, Experimental / Q000188:drug therapy; D051379:Mice; D008815:Mice, Inbred Strains; D008968:Molecular Conformation; D015394:Molecular Structure; D010051:Ovarian Neoplasms; D017239:Paclitaxel / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry* / Q000633:toxicity; D043823:Taxoids; D014407:Tumor Cells, Cultured
chemical_list: D000470:Alkaloids; D000970:Antineoplastic Agents; D001952:Bridged-Ring Compounds; D043823:Taxoids; C080625:taxane; D017239:Paclitaxel