title: Experimental technique for (laparoscopic) bowel anastomosis: transient endoluminally stented anastomosis (TESA).
abstract: A new technique for bowel anastomosis is presented. The principle of transient endoluminally stented anastomosis (TESA) is based on anastomosing the two bowel ends around a resorbable stent of polyglycolic acid (PGA) in seroserosal contact. To evaluate the feasibility of TESA for bowel anastomosis, laparoscopic colon anastomosis following sigma resection was performed in five juvenile pigs. Three animals were sacrificed 2 months postoperatively, and the anastomoses were examined radiologically and histologically. One animal was sacrificed at day 2, suffering from acute peritonitis due to small bowel leak but with regular colon anastomosis. One trial was terminated at the fourth postoperative day because of insufficiency of the colon anastomosis. Three animals did not have any complications during the 2-month follow-up. In these animals the colon anastomoses were not detectable radiologically at the time of death. The microscopic examination showed intact mucosal and muscular layers without foreign material. Our study demonstrates that laparoscopic application of TESA to colon anastomosis is a feasible method. These results will further stimulate our future research for an anastomosis technique avoiding remnant foreign material.
authors.affiliation: Clinic for Visceral Surgery, Department of Surgery, University Hospital, Zürich, Switzerland.
authors.forename: R A
authors.initials: RA
authors.lastname: Schmid
authors.forename: O
authors.initials: O
authors.lastname: Schöb
authors.forename: F
authors.initials: F
authors.lastname: Hetzer
authors.forename: R
authors.initials: R
authors.lastname: Schlumpf
authors.forename: M
authors.initials: M
authors.lastname: Spiess
authors.forename: F
authors.initials: F
authors.lastname: Largiadèr
mesh_terms: D000714:Anastomosis, Surgical / Q000295:instrumentation / Q000379:methods*; D000818:Animals; D003106:Colon / Q000033:anatomy & histology / Q000601:surgery*; D010535:Laparoscopy; D011100:Polyglycolic Acid; D015607:Stents; D013552:Swine
chemical_list: D011100:Polyglycolic Acid