title: Structures of the O-antigens of Proteus bacilli belonging to OX group (serogroups O1-O3) used in Weil-Felix test.
abstract: Structures of the O-specific polysaccharide chains of lipopolysaccharides from Proteus group OX strains (serogroups O1-O3) used as antigens in Weil-Felix test for diagnosis of rickettsiosis, were established. From them, the acid-labile polysaccharide of Proteus vulgaris OX19 (O1) is built up of the following branched pentasaccharide repeating units connected via a phosphate group: [structure in text] where QuiNAc stands for 2-acetamido-2,6-dideoxyglucose (N-acetylquinovosamine). The basis of serospecificity of the Proteus group OX antigens and their cross-reactivity with human anti-rickettsial antibodies is discussed.
authors.affiliation: Center of Microbiology and Virology, Polish Academy of Sciences, Lodz.
authors.forename: A
authors.initials: A
authors.lastname: Ziolkowski
authors.forename: A S
authors.initials: AS
authors.lastname: Shashkov
authors.forename: A S
authors.initials: AS
authors.lastname: Swierzko
authors.forename: S N
authors.initials: SN
authors.lastname: Senchenkova
authors.forename: F V
authors.initials: FV
authors.lastname: Toukach
authors.forename: M
authors.initials: M
authors.lastname: Cedzynski
authors.forename: K I
authors.initials: KI
authors.lastname: Amano
authors.forename: W
authors.initials: W
authors.lastname: Kaca
authors.forename: Y A
authors.initials: YA
authors.lastname: Knirel
mesh_terms: D000907:Antibodies, Bacterial / Q000276:immunology; D002236:Carbohydrate Conformation; D002240:Carbohydrate Sequence; D003429:Cross Reactions; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D008969:Molecular Sequence Data; D009005:Monosaccharides / Q000032:analysis; D019081:O Antigens / Q000737:chemistry* / Q000276:immunology; D009844:Oligosaccharides / Q000737:chemistry; D011513:Proteus mirabilis / Q000145:classification / Q000276:immunology*; D011514:Proteus vulgaris / Q000145:classification / Q000276:immunology*; D012281:Rickettsia / Q000276:immunology; D012282:Rickettsia Infections / Q000175:diagnosis / Q000276:immunology; D012698:Serologic Tests; D013403:Sugar Phosphates / Q000737:chemistry
chemical_list: D000907:Antibodies, Bacterial; D009005:Monosaccharides; D019081:O Antigens; D009844:Oligosaccharides; D013403:Sugar Phosphates