Linkage analysis in 16 families with incontinentia pigmenti.
A locus for the X-linked dominant genodermatosis incontinentia pigmenti (IP) has been linked to markers in Xq28. Here we report high lod scores for markers spanning the interval DXS52-DXYS154 using 16 families, providing further evidence for a single major X-linked IP locus.
Jouet
M
M
Cambridge University Department of Medicine, Addenbrooke's Hospital, UK.
Stewart
H
H
Landy
S
S
Yates
J
J
Yong
S L
SL
Harris
A
A
Garret
C
C
Hatchwell
E
E
Read
A
A
Donnai
D
D
Kenwrick
S
S
D002874:Chromosome Mapping; D004247:DNA / Q000032:analysis; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D005820:Genetic Testing; D006801:Humans; D007184:Incontinentia Pigmenti / Q000235:genetics*; D008126:Lod Score; D008297:Male; D010375:Pedigree; D011110:Polymorphism, Genetic; D014960:X Chromosome / Q000235:genetics*
D005819:Genetic Markers; D004247:DNA