title: Radionuclide angiography and ventilation/perfusion studies in two patients with systemic arterial supply to the basal segment of the left lung.
abstract: The findings of radionuclide studies in two adult men with systemic arterial supply to the basal segment of the left lung without sequestration are reported. Radionuclide angiography with Tc-99m human serum albumin-diethylenetriamine showed that the lung was perfused by the systemic circulation rather than by the pulmonary artery. Ventilation and perfusion scans with Xe-133 and Tc-99m MAA showed a V/Q mismatch in this area, suggesting the presence of normal bronchial communication without a pulmonary arterial supply. These results also suggest the presence of a left-to-left shunt in the well-ventilated lung in this area. MRI and conventional angiography showed an aberrant artery arising from the descending thoracic aorta, supplying the basal segment of the left lung without a pulmonary artery. In both patients, left lower lobectomy showed normal alveobronchial structures without sequestration. Radionuclide angiography and ventilation/perfusion imaging appear to be reliable noninvasive methods for diagnosing this rare anomaly with a left-to-left shunt.
authors.affiliation: Department of Radiology, Yamaguchi University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Suga
authors.forename: N
authors.initials: N
authors.lastname: Matsunaga
authors.forename: K
authors.initials: K
authors.lastname: Nishigauchi
authors.forename: S
authors.initials: S
authors.lastname: Yoneshiro
authors.forename: A
authors.initials: A
authors.lastname: Shimizu
authors.forename: K
authors.initials: K
authors.lastname: Takano
authors.forename: G
authors.initials: G
authors.lastname: Miura
authors.forename: I
authors.initials: I
authors.lastname: Ariyoshi
mesh_terms: D000328:Adult; D006801:Humans; D008168:Lung / Q000098:blood supply* / Q000000981:diagnostic imaging*; D008297:Male; D011651:Pulmonary Artery / Q000002:abnormalities*; D011875:Radionuclide Angiography; D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin; D014692:Ventilation-Perfusion Ratio
chemical_list: D019275:Radiopharmaceuticals; D013668:Technetium Tc 99m Aggregated Albumin