Multiple malignant meningiomas in a young cat.
A 2-year-old cat was presented with generalised muscle tremors and progressive fore- and hindlimb ataxia, 5 months after the initiation of chemotherapy for thymic lymphoma. The lymphoma was treated with combination chemotherapy (cyclophosphamide, vincristine and prednisolone), which resulted in remission. The neurological signs progressed to paralysis and the cat subsequently died. On autopsy, multiple meningiomas were diagnosed, which is an unusual finding. It is possible that the lymphoma chemotherapy resulted in the development of the multiple meningiomas as secondary malignancies.
Lobetti
R G
RG
Department of Medicine, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.
Nesbit
J W
JW
Miller
D B
DB
D000818:Animals; D001259:Ataxia / Q000209:etiology / Q000662:veterinary; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D064420:Drug-Related Side Effects and Adverse Reactions; D008223:Lymphoma / Q000188:drug therapy; D008297:Male; D008577:Meningeal Neoplasms / Q000473:pathology / Q000662:veterinary*; D008579:Meningioma / Q000473:pathology / Q000662:veterinary*; D009362:Neoplasm Metastasis; D016609:Neoplasms, Second Primary / Q000473:pathology / Q000662:veterinary*; D013953:Thymus Neoplasms / Q000188:drug therapy