title: Barrier between the supraglottis and the glottis: myth or reality?
abstract: Controversial opinions on the existence of a "barrier" between the supraglottic and glottic regions of the larynx are reported. Even if the two areas have different embryological derivations, there is no anatomic evidence of a "barrier" that could prevent supraglottic cancer from extending downward to the glottis. Numerous adequate pathologic studies, including whole organ sections, confirm that for advanced cancers, anatomic compartments delimiting the spread of the neoplastic process from the supraglottis to the glottis do not exist. Therefore, supraglottic laryngectomy should be performed not on the basis of embryological considerations, but on the basis of the actual extension of the neoplastic lesion.
authors.affiliation: Department of Otolaryngology, University of Padua, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Ferlito
authors.forename: J
authors.initials: J
authors.lastname: Olofsson
authors.forename: A
authors.initials: A
authors.lastname: Rinaldo
mesh_terms: D005931:Glottis / Q000033:anatomy & histology*; D006801:Humans; D007830:Larynx / Q000033:anatomy & histology*