title: Chemical modification of enzymes: kinetic aspects.
abstract: Important information on enzyme ligand interactions can be obtained when analyzing the kinetics of chemical modification reactions. In this article, several kinetic models of inactivation are discussed, along with the determination of enzyme-ligand dissociation constants and of the pK of enzyme reactive groups from chemical modification kinetic data.
authors.affiliation: Departamento de Ciencias Químicas, Facultad de Química y Biología, Universidad de Santiago de Chile, Chile.
authors.forename: E
authors.initials: E
authors.lastname: Cardemil
mesh_terms: D004789:Enzyme Activation / Q000502:physiology*; D004798:Enzymes / Q000378:metabolism*; D007700:Kinetics
chemical_list: D004798:Enzymes