[The influence of surfactant on the alveolar morphology in premature rabbits].
OBJECTIVE
To study the effects of treatment by surfactant manufactured by our institute on premature rabbits through observation of alveolar morphologic changes.


METHODS
The morphology of alveolar area in the premature rabbits were quantitatively studied by morphometry.


RESULTS
In the surfactant treated group, there was a reduction of alveolar number, and increases in alveolus area and the ratio of alveolus to alveolar septum. These changes were better than that in the control group.


CONCLUSIONS
Our surfactant was effective for respiratory distress syndrome in premature rabbits.
Liu
D
D
Capital Institute of Pediatrics, Beijing.
Hu
S
S
Lin
J
J
D000818:Animals; D000831:Animals, Newborn; D005260:Female; D005325:Fetal Organ Maturity / Q000187:drug effects; D007091:Image Processing, Computer-Assisted; D011650:Pulmonary Alveoli / Q000187:drug effects* / Q000196:embryology; D011663:Pulmonary Surfactants / Q000494:pharmacology*; D011817:Rabbits
D011663:Pulmonary Surfactants