title: Massive hemoptysis as the presenting manifestation in a child with histoplasmosis.
abstract: A previously healthy and asymptomatic 7-year-old white boy presented with a history of two episodes of hemoptysis productive of bright red blood in the 5 days preceding admission. After admission he developed massive hemoptysis that, on bronchoscopy, was noted to be emanating from the right lower lobe. An emergency right lower lobe resection was done. Pathological examination revealed hilar adenopathy and peripheral lesions with caseating granulomas containing yeast, morphologically consistent with Histoplasma capsulatum.
authors.affiliation: Department of Pediatrics, Ohio State University Medical Center, Columbus 43210, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Shaffer
authors.forename: W
authors.initials: W
authors.lastname: Barson
authors.forename: M
authors.initials: M
authors.lastname: Luquette
authors.forename: J I
authors.initials: JI
authors.lastname: Groner
authors.forename: M J
authors.initials: MJ
authors.lastname: Hogan
authors.forename: E
authors.initials: E
authors.lastname: Allen
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001999:Bronchoscopy; D002648:Child; D004359:Drug Therapy, Combination; D006469:Hemoptysis / Q000209:etiology* / Q000601:surgery; D006660:Histoplasmosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008168:Lung / Q000473:pathology; D008172:Lung Diseases, Fungal / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008297:Male; D011013:Pneumonectomy; D012008:Recurrence
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B