title: Bone marrow trephine biopsy in infants. European Neuroblastoma Study Group.
abstract: Central review of bone marrow trephine biopsies obtained between January 1990 and July 1996 from 282 children with neuroblastoma showed that 18% of cores from older children and an unacceptably high 36% from infants were inadequate (p = 0.0002). Centres should choose their operators for this invasive investigation of infants with more care in order to reduce the failure rate.
authors.affiliation: Department of Haematology, Royal Victoria Infirmary, Newcastle upon Tyne.
authors.forename: M M
authors.initials: MM
authors.lastname: Reid
authors.forename: B
authors.initials: B
authors.lastname: Roald
mesh_terms: D001706:Biopsy / Q000379:methods*; D001853:Bone Marrow / Q000473:pathology*; D001856:Bone Marrow Examination / Q000379:methods; D002983:Clinical Competence; D006801:Humans; D007223:Infant; D009447:Neuroblastoma / Q000473:pathology*