title: [The immuno-pathological damage of placenta and its types in pregnancy induced hypertension].
abstract: OBJECTIVE
  To study the immuno-pathological damage to placenta and its types in pregnancy induced hypertension (PIH).
  
  
  METHODS
  Using immunohistochemical technique (PAP method), authors studied the expression and localization of IgG, IgE, C3, C4, 5-HT on the villous vessels wall in PIH patients (n = 22) and normal pregnant women (n = 10), and observed the pathological changes of placenta with mast cell and connective tissue stain.
  
  
  RESULTS
  The immunostaining of IgG, IgE, C3, C4, and 5-HT were seen in the wall of villous vessels in PIH patients, the strong positive rate were 100%, 90%, 100%, 100%, 90% in severe PIH patients respectively, accompanied by aggregation of mast cells and lesions of villi and villous arterioles.
  
  
  CONCLUSIONS
  The immunological compound reaction and types 1, N of anaphylactic reactions took place in the placenta of PIH patients. It showed that the immunological factors were closely related to PIH.
authors.affiliation: Tongji Hospital, Tongji Medical University, Wuhan.
authors.forename: H
authors.initials: H
authors.lastname: Chen
authors.forename: Y
authors.initials: Y
authors.lastname: Huang
authors.forename: T
authors.initials: T
authors.lastname: Ma
mesh_terms: D000936:Antigen-Antibody Complex / Q000378:metabolism; D003176:Complement C3 / Q000378:metabolism; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000378:metabolism; D007074:Immunoglobulin G / Q000378:metabolism*; D010920:Placenta / Q000276:immunology / Q000473:pathology*; D011225:Pre-Eclampsia / Q000276:immunology* / Q000473:pathology*; D011247:Pregnancy; D012701:Serotonin / Q000378:metabolism
chemical_list: D000936:Antigen-Antibody Complex; D003176:Complement C3; D007074:Immunoglobulin G; D012701:Serotonin; D007073:Immunoglobulin E