title: [Effects of capsules on attachment of human periodontal ligament fibroblasts to root surface].
abstract: Inhibition of attachment of human periodontal ligament fibroblasts to root surface by three capsules were determined with the methods of trypan blue and L*a*b* color difference measurement. The results showed that capsule from porphyromonas gingivalis was the strongest one in inhibiting attachment and followed by the one from provotalla intermedia. Capsule from porphyromonas endodontolis was the weakest one. The values of color difference from that of control root surface were 11, 13, 8.28 and 4.09 respectively. Inhibitory mechanism of capsules may include a direct growth inhibition of fibroblasts and a decrease in attachment due to changes of root surface properties. There were a few fibroblasts attached to root surface with progressive periodontitis, this was a sharp contrast with that of control root surface. We deduce that long term affections of toxins including capsules and other substances led to changes of root surface with periodontitis, which made fibroblasts difficult to attach.
authors.affiliation: School of Stomatology, Fourth Military Medical University, Xian.
authors.forename: S
authors.initials: S
authors.lastname: Zhao
authors.forename: J
authors.initials: J
authors.lastname: Shi
authors.forename: M
authors.initials: M
authors.lastname: Xiao
mesh_terms: D016667:Bacterial Capsules / Q000494:pharmacology*; D002448:Cell Adhesion / Q000187:drug effects; D005347:Fibroblasts / Q000502:physiology; D006801:Humans; D010513:Periodontal Ligament / Q000166:cytology*; D010518:Periodontitis / Q000473:pathology; D014092:Tooth Root