Urodynamic abnormalities in two brothers with adrenomyeloneuropathy.
Adrenoleukodystrophy is an X-linked disorder characterized by loss of adrenal function and demyelinating nervous disease. A slowly progressive form, adrenomyeloneuropathy, has been described that can mimic multiple sclerosis. Two brothers are presented whose contrasting urodynamic findings are compatible with upper and mixed (upper and lower) motor neuron disease, respectively.
Walther
M M
MM
Urologic Oncology Branch, DCS/NCI/NIH, Bethesda, MD 20898-1502, USA.
Cutler
G B
GB
D000326:Adrenoleukodystrophy / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000175:diagnosis / Q000503:physiopathology; D001750:Urinary Bladder, Neurogenic / Q000209:etiology / Q000503:physiopathology*; D014563:Urodynamics