IL-10 prevents the generation of dendritic cells from CD14+ blood monocytes, promotes the differentiation to mature macrophages and stimulates endocytosis of FITC-dextran.
Allavena
P
P
Department of Immunology and Cell Biology, Mario Negri Institute, Milano, Italy.
Piemonti
L
L
Longoni
D
D
Bernasconi
S
S
Stoppacciaro
A
A
Ruco
L
L
Mantovani
A
A
D002454:Cell Differentiation / Q000187:drug effects; D003713:Dendritic Cells / Q000166:cytology* / Q000187:drug effects / Q000276:immunology*; D003911:Dextrans; D004705:Endocytosis / Q000187:drug effects; D005312:Fetal Blood / Q000166:cytology / Q000276:immunology; D016650:Fluorescein-5-isothiocyanate / Q000031:analogs & derivatives; D006801:Humans; D066298:In Vitro Techniques; D007231:Infant, Newborn; D016753:Interleukin-10 / Q000494:pharmacology*; D018950:Lipopolysaccharide Receptors / Q000378:metabolism; D008264:Macrophages / Q000166:cytology* / Q000187:drug effects / Q000276:immunology*; D009000:Monocytes / Q000166:cytology* / Q000187:drug effects / Q000276:immunology*; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology
D003911:Dextrans; D018950:Lipopolysaccharide Receptors; D014409:Tumor Necrosis Factor-alpha; C015219:fluorescein isothiocyanate dextran; D016753:Interleukin-10; D016650:Fluorescein-5-isothiocyanate