title: Congenital masses of the lung: changes in cross-sectional area during gestation.
abstract: OBJECTIVE
  We assessed the growth of congenital masses of the lung during gestation using computer-assisted planimetry.
  
  
  METHODS
  The prenatal sonograms of 8 fetuses with congenital masses of the lung were reviewed.
  
  
  RESULTS
  The cross-sectional area of the mass and chest were measured on the same transverse image using computer-assisted planimetry, and the percentage of the chest occupied by the mass was determined for each study. Four masses had pathologic features of type II congenital cystic adenomatoid malformation and intralobar sequestration (CCAM/ILS), 2 were type II CCAM, 1 was type I CCAM, and 1 was bronchial atresia with bronchiectasis. Four masses increased in cross-sectional area during gestation, 1 decreased, 2 were essentially unchanged, and 1 showed an initial increase in cross-sectional area followed by a decrease later in gestation. No consistent growth pattern was seen among masses with similar histologic characteristics. The percentage of the cross-sectional area of the chest occupied by the mass decreased in 7 fetuses and was virtually unchanged in 1 during gestation. All the fetuses survived to term; the infants had an uncomplicated postnatal course and underwent surgical resection of the mass during the first year of life.
  
  
  CONCLUSIONS
  This study showed that in a fetus with a congenital mass of the lung and a favorable clinical outcome, growth of the chest exceeds any growth of the mass that may occur and masses with the same pathologic diagnosis have different patterns of growth in utero.
authors.affiliation: Department of Radiology, Children's Hospital and Medical Center, Seattle, Washington 98105, USA.
authors.forename: W D
authors.initials: WD
authors.lastname: Winters
authors.forename: E L
authors.initials: EL
authors.lastname: Effmann
authors.forename: H V
authors.initials: HV
authors.lastname: Nghiem
authors.forename: D A
authors.initials: DA
authors.lastname: Nyberg
mesh_terms: D001982:Bronchial Diseases / Q000000981:diagnostic imaging*; D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging*; D005865:Gestational Age; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008168:Lung / Q000002:abnormalities / Q000196:embryology; D011247:Pregnancy; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal