title: [A case of transitional cell carcinoma of renal pelvis with extremely high serum levels of CA19-9 and CEA].
abstract: We report a case of transitional cell carcinoma of the renal pelvis with extremely high serum levels of carbohydrate antigen 19-9 (CA19-9) and carcinoembryonic antigen (CEA). A 69-year-old woman was admitted with gross hematuria. Imaging diagnosis revealed a tumor in the left renal pelvis and multiple liver and bone metastases. Serum levels of CA19-9 and CEA were 2,557 U/ml (normal < 36) and 523 ng/ml (normal < 3.8), respectively. She died of cancer progression 3 weeks after admission. An autopsy diagnosis was transitional cell carcinoma of the left renal pelvis. No abnormal findings were recognized in the gastrointestinal organs. Cancer cells showed a positive immunohistochemical staining for both CA19-9 and CEA.
authors.affiliation: Department of Urology, Jichi Medical School.
authors.forename: Y
authors.initials: Y
authors.lastname: Sugaya
authors.forename: M
authors.initials: M
authors.lastname: Ochi
authors.forename: S
authors.initials: S
authors.lastname: Hashimoto
authors.forename: J
authors.initials: J
authors.lastname: Muraki
authors.forename: T
authors.initials: T
authors.lastname: Morita
authors.forename: Y
authors.initials: Y
authors.lastname: Kobayashi
authors.forename: S
authors.initials: S
authors.lastname: Nakamura
authors.forename: A
authors.initials: A
authors.lastname: Tokue
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood*; D001859:Bone Neoplasms / Q000556:secondary; D018395:CA-19-9 Antigen / Q000097:blood*; D002272:Carcinoembryonic Antigen / Q000097:blood*; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis* / Q000556:secondary; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000473:pathology; D007682:Kidney Pelvis; D008113:Liver Neoplasms / Q000556:secondary
chemical_list: D014408:Biomarkers, Tumor; D018395:CA-19-9 Antigen; D002272:Carcinoembryonic Antigen