title: Localisation of the classical DNA satellites on human chromosomes as determined by primed in situ labelling (PRINS).
abstract: The chromosomal localisation and relative amounts in humans of the classical DNA satellites I, II and III have been determined by using the primed in situ labelling reaction with a variety of oligonucleotide primers. The centromeres of seven of the human chromosomes, viz. nos 6, 8, 11, 12, 18, 19 and X, are not identifiably marked by any of the primers. A possible phylogenetic explanation of this is suggested and the possible relationship of the classical satellites to the function of the centromere is discussed.
authors.affiliation: Institute of Human Genetics, Aarhus University, Denmark.
authors.forename: A J
authors.initials: AJ
authors.lastname: Therkelsen
authors.forename: A
authors.initials: A
authors.lastname: Nielsen
authors.forename: S
authors.initials: S
authors.lastname: Kølvraa
mesh_terms: D002874:Chromosome Mapping; D017931:DNA Primers; D004276:DNA, Satellite; D006801:Humans; D017403:In Situ Hybridization / Q000379:methods; D008297:Male
chemical_list: D017931:DNA Primers; D004276:DNA, Satellite