[Emotional stress and sleep: a study of adrenalectomized rats].
Polygraphic recordings were performed during 12-h dark period in 18 adrenalectomized rats with implanted electrodes for ECoG and EMG under normal conditions and following 1-h immobilization period. The exposure of rats to emotional immobilization stress evoked a highly significant increase in sleep which was especially pronounced for the slow wave sleep (about 40% above the control value). The immobilization effect was completely abolished by preliminary treatment with dexametazone (1 mg/kg subcutaneously). Thus, adrenal steroids are involved into the interrelation between the emotional stress and sleep as a link in a negative feedback loop.
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D000311:Adrenal Glands / Q000187:drug effects / Q000502:physiology*; D000315:Adrenalectomy; D000818:Animals; D003907:Dexamethasone / Q000494:pharmacology; D004569:Electroencephalography / Q000187:drug effects; D004576:Electromyography / Q000187:drug effects; D005938:Glucocorticoids / Q000494:pharmacology; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012149:Restraint, Physical; D012890:Sleep / Q000187:drug effects / Q000502:physiology*; D013315:Stress, Psychological / Q000503:physiopathology*; D013997:Time Factors
D005938:Glucocorticoids; D003907:Dexamethasone