title: Familial focal segmental glomerulosclerosis: nine cases in four families and review of the literature.
abstract: Idiopathic focal segmental glomerulosclerosis (FSGS) is a common cause of glomerular disease. Although previous case reports suggesting a familial form of the disease exist in the literature, its significance has not been emphasized. We report on our experience with nine cases in four families, as well as a review of the literature, and provide evidence that a familial form of FSGS might represent a distinct genotypic and phenotypic subset of idiopathic FSGS.
authors.affiliation: Department of Medicine, The Brookdale University Hospital and Medical Center, Brooklyn, NY 11212, USA.
authors.forename: P F
authors.initials: PF
authors.lastname: Faubert
authors.forename: J G
authors.initials: JG
authors.lastname: Porush
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D005923:Glomerulosclerosis, Focal Segmental / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007668:Kidney / Q000473:pathology; D008297:Male; D008875:Middle Aged