Collagenous colitis and cimetidine.
We report a case of a 62-year-old man who developed watery diarrhoea after starting treatment with cimetidine for dyspepsia. Macroscopically, sigmoidoscopy and colonoscopy were normal. Histology revealed features consistent with a diagnosis of collagenous colitis. The diarrhoea is responding to treatment with prednisolone and withdrawal of cimetidine. We conclude that the collagenous colitis may have been drug induced.
Duncan
H D
HD
Department of Gastroenterology and Nutrition, Central Middlesex Hospital NHS Trust, London, UK.
Talbot
I C
IC
Silk
D B
DB
D000930:Antidiarrheals / Q000627:therapeutic use; D001706:Biopsy; D002927:Cimetidine / Q000009:adverse effects*; D003092:Colitis / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D003094:Collagen; D003967:Diarrhea / Q000139:chemically induced; D006801:Humans; D008297:Male; D008875:Middle Aged
D000930:Antidiarrheals; D002927:Cimetidine; D003094:Collagen