Sclerosing cholangitis associated with hypereosinophilic syndrome.
A 15-year-old male with hypereosinophilic syndrome was admitted to our hospital because of general malaise and abnormal liver function tests. Endoscopic retrograde cholangiopancreatography demonstrated bile duct changes consistent with primary sclerosing cholangitis. The patient's liver profile tests returned to normal after treatment with prednisolone and ursodeoxycholic acid. In this case, eosinophils might have played an important role in the pathogenesis of the bile duct lesion.
Ichikawa
N
N
Department of Rheumatology, Institute of Rheumatology, Tokyo Women's Medical College.
Taniguchi
A
A
Akama
H
H
Ishiguro
H
H
Kurihara
T
T
Terai
C
C
Hara
M
M
Kashiwazaki
S
S
D000293:Adolescent; D015209:Cholangitis, Sclerosing / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D017681:Hypereosinophilic Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D011241:Prednisone / Q000627:therapeutic use; D014580:Ursodeoxycholic Acid / Q000627:therapeutic use
D014580:Ursodeoxycholic Acid; D011241:Prednisone