title: [Quantification of lamellar bodies in amniotic fluid: a method for the evaluation of fetal pulmonary maturity].
abstract: It was tried to know the counting up of lamellar bodies in amniotic fluid, as a test of fetal pulmonary maturity, comparing it with neonatal evolution. 31 samples of amniotic fluid of different ages of gestation, were obtained, lamellar bodies were quantified with a standard equipment of hematic counting, and comparing with neonatal evolution, sensitivity, specificity, positive predictive value, and negative predictive value are established. The established concentration of 30,000/l by comparison with Lecitine/Esfingomieline and with Fosfatidilglycerol was used. From 29 patients with counts greater than 30,000, none presented Respiratory Difficulty syndrome (SDR); and from two patients with lower counts, one presented SDR and one had normal neonatal evolution. Sensitivity was 96%; specificity was 100%; predictive positive value, 50%; and negative predictive value was 100%. Because of this, the test is so useful in practice. Its statistical values, its minimal cost; easiness to do, and equipment availability, justify this test as a first election.
authors.affiliation: Centro de Ginecología y Obstetricia de Monterrey SA.
authors.forename: J
authors.initials: J
authors.lastname: Carrillo
authors.forename: E
authors.initials: E
authors.lastname: García
authors.forename: C
authors.initials: C
authors.lastname: Lozano
authors.forename: P
authors.initials: P
authors.lastname: Galache
authors.forename: J
authors.initials: J
authors.lastname: Lozano
authors.forename: H
authors.initials: H
authors.lastname: González
mesh_terms: D000653:Amniotic Fluid / Q000737:chemistry*; D005260:Female; D005325:Fetal Organ Maturity; D005865:Gestational Age; D006801:Humans; D008168:Lung / Q000196:embryology*; D015388:Organelles / Q000648:ultrastructure; D011237:Predictive Value of Tests; D011247:Pregnancy