[The genetic bases of the lipid metabolic disorders in atherosclerosis].
The development of dyslipoproteinemia is to a large extent genetically determined. The mutations in gene controlling receptor to lipoproteids of low density, the genes Apo B, Apo A-1, and Apo E have a dominant role in the disturbance of lipid metabolism. The development of atherosclerosis at young age is apparently associated with the mutations in gene of receptors, in the gene Apo B and some mutations in a cluster of the genes A-I--CIII--AIV.
Tselĭko
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D001053:Apolipoproteins / Q000097:blood / Q000235:genetics; D001161:Arteriosclerosis / Q000097:blood / Q000235:genetics*; D005796:Genes / Q000235:genetics; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood / Q000235:genetics; D008055:Lipids / Q000097:blood / Q000235:genetics*; D009154:Mutation / Q000235:genetics; D018110:Receptors, Lipoprotein / Q000097:blood / Q000235:genetics
D001053:Apolipoproteins; D008055:Lipids; D018110:Receptors, Lipoprotein