Effects of malnutrition and atherosclerosis on the fatty acid composition of plasma phospholipids in the elderly.
The fatty acid profiles of plasma phospholipids have been compared in 53 elderly subjects suffering from malnutrition (group U, 17 subjects) or from atherosclerosis (group A, 15 subjects). A control group was also included in the study (group C, 21 subjects). Main differences were observed in phosphatidylcholine (PC). In group U, the proportion of monounsaturated fatty acids increased in PC, which was reflected by an increase in unsaturated fatty acids without significant modification of essential fatty acids. In group A, no major modification has been observed statistically, although the proportion of saturated fatty acids tended to increase.
Bamberg
T
T
Centre de Nutrition Humaine, Nancy, France.
Pelletier
X
X
Blain
H
H
Jeandel
C
C
Debry
G
G
D000368:Aged; D000375:Aging / Q000097:blood*; D001161:Arteriosclerosis / Q000097:blood*; D002308:Cardiolipins / Q000097:blood; D005227:Fatty Acids / Q000097:blood*; D006801:Humans; D008244:Lysophosphatidylcholines / Q000097:blood; D009748:Nutrition Disorders / Q000097:blood*; D010713:Phosphatidylcholines / Q000097:blood; D010714:Phosphatidylethanolamines / Q000097:blood; D010716:Phosphatidylinositols / Q000097:blood; D010743:Phospholipids / Q000097:blood*; D013109:Sphingomyelins / Q000097:blood
D002308:Cardiolipins; D005227:Fatty Acids; D008244:Lysophosphatidylcholines; D010713:Phosphatidylcholines; D010714:Phosphatidylethanolamines; D010716:Phosphatidylinositols; D010743:Phospholipids; D013109:Sphingomyelins