Effects of exogenous surfactant on neonates supported by extracorporeal membrane oxygenation.
OBJECTIVE
The purpose of this study was to evaluate the impact of exogenous surfactant on the duration of extracorporeal membrane oxygenation needed to support neonates.


METHODS
Retrospective case review.


RESULTS
The duration of extracorporeal membrane oxygenation decreased from 112 +/- 43.3 hours to 76 +/- 17.9 hours. There was no difference in duration of mechanical ventilation, duration of supplemental oxygen, incidence of chronic lung disease, or length of hospital stay.


CONCLUSIONS
Surfactant administered soon after initiation of extracorporeal membrane oxygenation results in a significant reduction in the duration of extracorporeal support for neonates.
Stillerman
L R
LR
Department of Respiratory Care, James Whitcomb Riley Hospital for Children, Indiana University School of Medicine, Indianapolis 46202-5210, USA.
Gunn
S B
SB
Hart
J C
JC
Engle
W A
WA
D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006801:Humans; D007231:Infant, Newborn / Q000502:physiology*; D008297:Male; D011663:Pulmonary Surfactants / Q000627:therapeutic use*; D012189:Retrospective Studies; D013997:Time Factors
D011663:Pulmonary Surfactants