title: Determination of the PCO2-dependent component of the H+ concentration in venous and arterial blood plasma.
abstract: In normal venous blood plasma, the regression line of [H+] plotted against the PCO2 was linear against the square root of PCO2. Sequential measurements in venous and arterial blood of PCO2 and [H+] showed that the venous-arterial (V-A) difference in [H+] was linearly related to the V-A difference in the square root of PCO2, the regression line having the same slope as that of the venous [H+] plotted against the square root of PCO2. These findings suggested that the venous [H+] on the regression line represents the PCO2-dependent component, of [H+], [H+]*. The PCO2-independent component, delta [H+], can then be given by subtracting [H+]* from the measured [H+]. The delta [H+] in venous blood agreed well with that in arterial blood with a correlation coefficient of 0.99, supporting the validity of the value of [H+]*.
authors.affiliation: Geriatric Respiratory Research Center, Nishimaruyama Hospital, Sapporo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Mochizuki
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001158:Arteries; D001774:Blood Chemical Analysis / Q000706:statistics & numerical data; D002245:Carbon Dioxide / Q000097:blood*; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D010949:Plasma / Q000378:metabolism*; D012016:Reference Values; D012044:Regression Analysis; D014680:Veins
chemical_list: D002245:Carbon Dioxide