title: Sonography and MRI of experimental muscle injuries.
abstract: After sonographical examination with a 7.5-MHz linear array scanner, we created an experimental muscle injury of known site and location on 28 New Zealand white rabbits by stabbing them with a scalpel in the supraspinatus muscle. The changes in the healing process were followed and documented by sonography and magnetic resonance imaging (MRI) before and 2, 5, 11, 14, 36 and 64 days after injury. The changes in sonography and MRI followed a regular course. Ultrasound revealed an echo-poor area after injury with ever increasing echogenicity from the 14th day. Strong reflexes were found after 2 months. MRI showed few changes, only a slight increase of signal intensity, but a characteristic curve of calculated T2-times (a program of the MRI software). The interpretation of the sonographical picture in histopathological terms remained limited. The development of a hematoma and of fibrous scars can be followed up by sonography, but it is not possible to determine the point of time after injury very accurately. Nevertheless, sonography is a method of great value in the diagnosis of muscle injuries and, given certain limits, in the follow-up of the healing process, too. The significance of MRI can be increased by calculations with the implemented software, as in our study calculated T2-times produced a characteristic curve reflecting the shift of fluids after muscle injury.
authors.affiliation: Orthopädische Klinik, Johannes-Gutenberg-Universität Mainz, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Küllmer
authors.forename: K W
authors.initials: KW
authors.lastname: Sievers
authors.forename: J D
authors.initials: JD
authors.lastname: Rompe
authors.forename: M
authors.initials: M
authors.lastname: Nägele
authors.forename: U
authors.initials: U
authors.lastname: Harland
mesh_terms: D000818:Animals; D001415:Back; D008279:Magnetic Resonance Imaging; D008297:Male; D018482:Muscle, Skeletal / Q000000981:diagnostic imaging / Q000293:injuries* / Q000473:pathology; D011817:Rabbits; D014463:Ultrasonography; D014945:Wound Healing; D014951:Wounds, Stab / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology