Immortalized cell lines with dendritic morphology derived from mice lacking both type I and type II interferon receptors present MHC II restricted antigen to T cells and induce mixed leukocyte reactions.
Nunez
R
R
Institute for Virology, Veterinary Faculty, University of Zürich, Switzerland.
Ackermann
M
M
Suter
M
M
D000818:Animals; D017951:Antigen Presentation; D000941:Antigens; D002454:Cell Differentiation; D002460:Cell Line; D002472:Cell Transformation, Viral; D003713:Dendritic Cells / Q000166:cytology / Q000276:immunology*; D000949:Histocompatibility Antigens Class II / Q000378:metabolism*; D066298:In Vitro Techniques; D007370:Interferon Type I / Q000378:metabolism; D007371:Interferon-gamma / Q000378:metabolism; D008213:Lymphocyte Activation; D007959:Lymphocyte Culture Test, Mixed; D051379:Mice; D018345:Mice, Knockout; D010047:Ovalbumin / Q000276:immunology; D017471:Receptors, Interferon / Q000172:deficiency* / Q000235:genetics; D013601:T-Lymphocytes / Q000276:immunology*
D000941:Antigens; D000949:Histocompatibility Antigens Class II; D007370:Interferon Type I; D017471:Receptors, Interferon; D007371:Interferon-gamma; D010047:Ovalbumin