title: Focal hyperemia on RBC blood-flow imaging. A scintigraphic marker of arterioportal venous shunting in hepatic cavernous hemangiomas?
abstract: OBJECTIVE
  To investigate the significance of increased perfusion associated with some hepatic hemangiomata during radionuclide blood volume imaging.
  
  
  METHODS
  Immediate dynamic planar projections and delayed SPECT imaging of a hepatic lesion were obtained after the administration of Tc-99m-labeled RBC. Scintigraphic data were compared with X-ray CT, contrast angiography and postresection histopathology.
  
  
  RESULTS
  A surgically proven, cavernous hemangioma with typical findings on delayed radionuclide blood-pool imaging showed markedly increased perfusion by scintigraphy. This correlated with arterioportal venous shunting (AVPS) on contrast angiography.
  
  
  CONCLUSIONS
  Increased perfusion on radionuclide blood-volume imaging of hepatic hemangiomata may be a scintigraphic marker of AVPS. This may serve to identify patients with increased risk for spontaneous rupture or may identify them for the development of portal hypertension.
authors.affiliation: Department of Internal Medicine Nuclear Medicine, University of Michigan Medical Center, Ann Arbor 48109-0028, USA.
authors.forename: B A
authors.initials: BA
authors.lastname: Dwamena
authors.forename: K K
authors.initials: KK
authors.lastname: Belcher
authors.forename: N
authors.initials: N
authors.lastname: Dasika
authors.forename: K A
authors.initials: KA
authors.lastname: Frey
mesh_terms: D001810:Blood Volume; D004912:Erythrocytes; D005260:Female; D006392:Hemangioma, Cavernous / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D006940:Hyperemia / Q000000981:diagnostic imaging*; D008113:Liver Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging* / Q000601:surgery; D008875:Middle Aged; D011169:Portal Vein / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals; D012307:Risk Factors; D013670:Sodium Pertechnetate Tc 99m; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D019275:Radiopharmaceuticals; D013670:Sodium Pertechnetate Tc 99m