Lack of arrhythmogenicity with ST-segment elevation during high-dose of dobutamine atropine stress in patients with documented or suspected coronary artery disease.
The angiographic, echocardiographic, and electrocardiographic correlates of ST-segment elevation during high-dose dobutamine-atropine stress were prospectively looked at in a group of high-risk patients. Unlike exercise-induced ST elevation, ST-segment elevation with dobutamine-atropine stress, while indicating transmural ischemia, did not increase rate of arrhythmias and hence by itself may not be an indication to terminate the test.
Kamalesh
M
M
Department of Medicine, University of Oklahoma Health Sciences Center and Department of Veterans Affairs Medical Center, Oklahoma City, USA.
Chandrasekaran
K
K
Sivaram
C A
CA
Thadani
U
U
D000368:Aged; D000889:Anti-Arrhythmia Agents; D001285:Atropine; D002316:Cardiotonic Agents / Q000494:pharmacology; D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis*; D004280:Dobutamine / Q000494:pharmacology; D004452:Echocardiography; D005080:Exercise Test; D006329:Heart Conduction System / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged
D000889:Anti-Arrhythmia Agents; D002316:Cardiotonic Agents; D004280:Dobutamine; D001285:Atropine