title: [Pregnancy induced hypertension].
abstract: Hypertension remains a leading cause of perinatal morbidity and mortality. Classification of the hypertensive disorders of pregnancy is 1) preeclampsia-eclampsia, 2) chronic hypertension, 3) chronic hypertension with superimposed preeclampsia-eclampsia. Preeclampsia is characterized by the triad of hypertension, proteinuria, and edema but these findings are not specific. Although the etiology and pathogenesis of preeclampsia remain unknown, several factors such as abnormalities in prostaglandin systems, in coagulation process, derangements of the endothelium and so on. Management of preeclampsia is bed rest, aspirin administration, antihypertensive agents (beta-blockers, hydralazine, alpha-methyldopa) would be used for reduction of blood pressure.
authors.affiliation: Saitama Medical School, Department of Nephrology.
authors.forename: H
authors.initials: H
authors.lastname: Suzuki
mesh_terms: D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001510:Bed Rest; D000075202:Contraindications; D005260:Female; D006801:Humans; D006830:Hydralazine / Q000627:therapeutic use; D006973:Hypertension / Q000628:therapy; D008750:Methyldopa / Q000627:therapeutic use; D011225:Pre-Eclampsia / Q000209:etiology / Q000628:therapy; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000628:therapy
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D006830:Hydralazine; D008750:Methyldopa