title: Granuloma faciale: successful treatment of nine cases with a combination of cryotherapy and intralesional corticosteroid injection.
abstract: BACKGROUND
  Granuloma faciale is a rare disorder characterized by asymptomatic papules, nodules, and plaques on the face. Although the exact pathogenesis of this disease in unclear, it is considered a variant of leukocytoclastic vasculitis confined to the skin. Several medical and surgical methods have been used to treat it with variable results.
  
  
  METHODS
  We report nine cases of granuloma faciale treated with a combination of cryotherapy with liquid nitrogen and intralesional injection of corticosteroids.
  
  
  RESULTS
  The lesions cleared completely in all of the patients without any side-effects. No recurrences have been observed.
  
  
  CONCLUSIONS
  Cryotherapy with liquid nitrogen, followed by intralesional injection of corticosteroids, is a safe and effective method to treat granuloma faciale.
authors.affiliation: Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, Iran.
authors.forename: B
authors.initials: B
authors.lastname: Dowlati
authors.forename: A
authors.initials: A
authors.lastname: Firooz
authors.forename: Y
authors.initials: Y
authors.lastname: Dowlati
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D003452:Cryosurgery / Q000379:methods*; D005148:Facial Dermatoses / Q000628:therapy*; D005260:Female; D006099:Granuloma / Q000628:therapy*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome; D014222:Triamcinolone Acetonide / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000305:Adrenal Cortex Hormones; D014222:Triamcinolone Acetonide