Direct isoform analysis of high-mannose-containing glycoproteins by on-line capillary electrophoresis electrospray mass spectrometry.
Yeung
B
B
Biopharmaceutical Characterization and Analysis, Genetics Institute, Inc., Andover, Massacheusetts 01810.
Porter
T J
TJ
Vath
J E
JE
D000595:Amino Acid Sequence; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins / Q000032:analysis / Q000737:chemistry; D002852:Chromatography, Ion Exchange; D019075:Electrophoresis, Capillary / Q000379:methods*; D006023:Glycoproteins / Q000032:analysis* / Q000737:chemistry; D006801:Humans; D008358:Mannose / Q000032:analysis*; D013058:Mass Spectrometry / Q000379:methods*; D008968:Molecular Conformation; D008969:Molecular Sequence Data; D008970:Molecular Weight; D011994:Recombinant Proteins / Q000032:analysis / Q000737:chemistry; D012260:Ribonucleases / Q000032:analysis / Q000737:chemistry; D012815:Signal Processing, Computer-Assisted; D016212:Transforming Growth Factor beta
C525718:BMP2 protein, human; D055396:Bone Morphogenetic Protein 2; D019485:Bone Morphogenetic Proteins; D006023:Glycoproteins; D011994:Recombinant Proteins; D016212:Transforming Growth Factor beta; C499469:recombinant human bone morphogenetic protein-2; D012260:Ribonucleases; C029600:ribonuclease B; D008358:Mannose