title: Cyclosporin A in the treatment of adult onset Still's disease.
abstract: OBJECTIVE
  To determine whether cyclosporin A (CyA) is a useful option in the treatment of adult onset Still's disease (ASD).
  
  
  METHODS
  Low dose CyA was given to 6 patients with chronic or relapsing ASD who had not been prescribed any other second line agents during the previous 6 mo.
  
  
  RESULTS
  The disease completely remitted in 4 patients and improved markedly in the remaining 2. The corticosteroid requirement was substantially reduced in all cases. Tolerability was rated good or very good by all patients but one, who reported good tolerance to CyA only in a new formulation.
  
  
  CONCLUSIONS
  CyA may be included among the second line agents used in the treatment of refractory ASD.
authors.affiliation: Rheumatology Unit, University of Milan, G. Pini Orthopaedic Institute, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Marchesoni
authors.forename: G P
authors.initials: GP
authors.lastname: Ceravolo
authors.forename: N
authors.initials: N
authors.lastname: Battafarano
authors.forename: A
authors.initials: A
authors.lastname: Rossetti
authors.forename: S
authors.initials: S
authors.lastname: Tosi
authors.forename: F
authors.initials: F
authors.lastname: Fantini
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D018501:Antirheumatic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D016572:Cyclosporine / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D016706:Still's Disease, Adult-Onset / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome
chemical_list: D018501:Antirheumatic Agents; D016572:Cyclosporine