Oocyte differentiation: a motor makes a difference.
In a variety of developmental systems, asymmetric mitoses precede, and are essential for, cellular differentiation. Recent studies demonstrate a role for the motor protein cytoplasmic dynein in generating the mitotic asymmetries that lead to Drosophila oocyte differentiation.
Theurkauf
W E
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Department of Biochemistry and Cell Biology, State University of New York at Stony Brook Stony Brook, New York 11764-5215, USA. theurk@mcbsgi.bio.sunysb.edu
D000818:Animals; D017173:Caenorhabditis elegans; D004330:Drosophila; D004398:Dyneins / Q000502:physiology*; D008938:Mitosis; D009866:Oogenesis / Q000502:physiology*
D004398:Dyneins