title: Collagenous colitis and cimetidine.
abstract: We report a case of a 62-year-old man who developed watery diarrhoea after starting treatment with cimetidine for dyspepsia. Macroscopically, sigmoidoscopy and colonoscopy were normal. Histology revealed features consistent with a diagnosis of collagenous colitis. The diarrhoea is responding to treatment with prednisolone and withdrawal of cimetidine. We conclude that the collagenous colitis may have been drug induced.
authors.affiliation: Department of Gastroenterology and Nutrition, Central Middlesex Hospital NHS Trust, London, UK.
authors.forename: H D
authors.initials: HD
authors.lastname: Duncan
authors.forename: I C
authors.initials: IC
authors.lastname: Talbot
authors.forename: D B
authors.initials: DB
authors.lastname: Silk
mesh_terms: D000930:Antidiarrheals / Q000627:therapeutic use; D001706:Biopsy; D002927:Cimetidine / Q000009:adverse effects*; D003092:Colitis / Q000139:chemically induced* / Q000188:drug therapy / Q000473:pathology; D003094:Collagen; D003967:Diarrhea / Q000139:chemically induced; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D000930:Antidiarrheals; D002927:Cimetidine; D003094:Collagen