Probing bacterial gene expression within host cells.
The study of bacterial gene expression in the host environment is critical to our understanding of the disease process. New research tools, such as luciferase and green fluorescent protein, provide the means to measure bacterial responses to the intracellular environment with minimal perturbations and with single-cell resolution.
Valdivia
R H
RH
Dept of Microbiology and Immunology, Stanford University School of Medicine, CA 94305, USA. valdivia@cmgm.stanford.edu
Falkow
S
S
D001419:Bacteria / Q000235:genetics* / Q000378:metabolism*; D001426:Bacterial Proteins / Q000032:analysis / Q000378:metabolism; D003593:Cytoplasm / Q000378:metabolism*; D005456:Fluorescent Dyes; D015870:Gene Expression; D005798:Genes, Bacterial; D017930:Genes, Reporter / Q000502:physiology; D013194:Staining and Labeling / Q000379:methods*
D001426:Bacterial Proteins; D005456:Fluorescent Dyes