[Electrophoretic mobility and oxidizing status of rat blood erythrocytes at scald trauma].
On model of scald trauma the correlation of electrophoretic mobility of rat blood erythrocytes with intensity of lipid oxidation of erythrocyte membranes and with activity of catalase were studied. It is shown that in dynamics of scald disease development the erythrocyte mobility decreases, the velocity of oxidizing ability of their lipids increases and the protective action of blood antioxidation system is blocked. It is found that there is a close dependence between the level of oxidative processes and electrogenic properties of erythrocytes at the height of manifestation of scald toxaemia. A conclusion was made that the oppressing influence of increasing lipid oxidizing ability a on electrokinetic potential of erythrocytes is of a threshold nature and is realized through change in the membranes' state of these cells.
Matiushichev
V B
VB
Shamratova
V G
VG
Akhunova
A R
AR
Gerchikov
A Ia
AIa
D000818:Animals; D002056:Burns / Q000097:blood* / Q000473:pathology; D002374:Catalase / Q000378:metabolism; D004591:Electrophoresis, Polyacrylamide Gel; D004910:Erythrocyte Membrane / Q000201:enzymology / Q000378:metabolism; D004912:Erythrocytes / Q000166:cytology / Q000378:metabolism* / Q000473:pathology; D015227:Lipid Peroxidation / Q000502:physiology; D008297:Male; D010084:Oxidation-Reduction; D051381:Rats; D013262:Stevens-Johnson Syndrome / Q000378:metabolism
D002374:Catalase