title: Tissue characteristics of root resorption areas in transplanted maxillary canines.
abstract: The aim of the present study was to describe some histopathologic features of tissues collected from root resorption areas of maxillary canines after transalveolar transplantation surgery. In 8 of 101 transplanted canines, complications including cervical root resorption occurred between 6 and 11 years after treatment. The resorptive processes were located at the supra-alveolar portions of the distal and/or mesial aspects of the teeth and were scheduled for treatment involving surgical exploration. The resorption cavities, which extended from the cementoenamel junction to a position immediately below the bone crest, were filled with a granulation tissue. In four of the diagnosed complication cases, this granulation tissue was carefully excised concomitant with the adjacent gingival tissue after flap elevation and placed in a buffered fixative. After proper soft-tissue healing, the cavities were filled with a glass-ionomer material. The collected biopsy specimens were, after fixation and, in one case, decalcification in ethylenediaminetetraacetic acid, dehydrated and embedded in Epon. Sections 3 microns thick were produced, stained in periodic acid-Schiff and toluidine blue, and used for histometric and morphometric analyses. The histologic analysis showed that the dissected tissue harbored well-encapsulated areas of inflammatory infiltrates. The lesions comprised a relatively low volume of collagen and a large number of inflammatory cells, predominantly lymphocytes.
authors.affiliation: Department of Periodontology, Göteborg University, Sweden.
authors.forename: T
authors.initials: T
authors.lastname: Berglundh
authors.forename: B
authors.initials: B
authors.lastname: Thilander
authors.forename: S
authors.initials: S
authors.lastname: Sagne
mesh_terms: D000328:Adult; D000539:Alveolar Process / Q000473:pathology; D001706:Biopsy; D003094:Collagen; D004396:Coloring Agents; D003481:Cuspid / Q000473:pathology / Q000637:transplantation*; D003648:Decalcification Technique; D003793:Dental Restoration, Permanent; D004492:Edetic Acid; D004853:Epoxy Resins; D005260:Female; D005500:Follow-Up Studies; D005890:Gingivectomy / Q000379:methods; D005899:Glass Ionomer Cements; D006097:Granulation Tissue / Q000473:pathology; D006801:Humans; D007249:Inflammation; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D008437:Maxilla / Q000601:surgery; D008875:Middle Aged; D010503:Periodic Acid-Schiff Reaction; D016613:Plastic Embedding; D012391:Root Resorption / Q000473:pathology* / Q000628:therapy; D016707:Tissue Fixation; D014048:Tolonium Chloride; D019237:Tooth Cervix / Q000473:pathology; D014092:Tooth Root / Q000473:pathology; D014945:Wound Healing
chemical_list: D004396:Coloring Agents; D004853:Epoxy Resins; D005899:Glass Ionomer Cements; D014048:Tolonium Chloride; C004875:EPON; D003094:Collagen; D004492:Edetic Acid