ABT-491, a highly potent and selective PAF antagonist, inhibits nasal vascular permeability associated with experimental allergic rhinitis in brown Norway rats.
Albert
D H
DH
Department 47J, Abbott Laboratories, Abbott Park, IL 60064-3500, USA.
Tapang
P
P
Morgan
D W
DW
Curtin
M L
ML
Sheppard
G S
GS
Davidsen
S K
SK
Summers
J B
JB
Carter
G W
GW
D000818:Animals; D002199:Capillary Permeability / Q000187:drug effects*; D007093:Imidazoles / Q000494:pharmacology*; D007211:Indoles / Q000494:pharmacology*; D007700:Kinetics; D009297:Nasal Mucosa / Q000098:blood supply*; D010972:Platelet Activating Factor / Q000037:antagonists & inhibitors* / Q000494:pharmacology; D051381:Rats; D011914:Rats, Inbred BN; D012221:Rhinitis, Allergic, Perennial / Q000503:physiopathology*
D007093:Imidazoles; D007211:Indoles; D010972:Platelet Activating Factor; C107116:ABT 491