Double-blind trial of flumazenil in hemiballismus.
Three patients with hemiballismus received intravenous flumazenil and placebo in a double-blind cross-over study aimed to investigate whether an antagonistic action at the level of the GABA-benzodiazepine receptors may improve choreoballistic movements. No clinical benefit was seen.
Kulisevsky
J
J
Department of Neurology, Sant Pau Hospital, Autonomous University of Barcelona, Spain.
Avila
A
A
Berthier
M L
ML
Barbanoj
M
M
D000368:Aged; D000369:Aged, 80 and over; D018592:Cross-Over Studies; D004311:Double-Blind Method; D005260:Female; D005442:Flumazenil / Q000627:therapeutic use*; D018756:GABA Antagonists / Q000627:therapeutic use*; D006801:Humans; D009069:Movement Disorders / Q000188:drug therapy*; D010919:Placebos
D018756:GABA Antagonists; D010919:Placebos; D005442:Flumazenil