Laryngopharyngeal sensory testing with modified barium swallow as predictors of aspiration pneumonia after stroke.
Improved diagnostic tests that can accurately identify subjects at high risk for aspiration pneumonia (AP) are needed. One measure of this accuracy is the false-negative rate (FNR), which determines the failure of a test to identify a group at high risk. This study compares FNRs for AP among dysphagic stroke patients for two prognostic techniques: modified barium swallow (MBS) alone and MBS combined with laryngopharyngeal sensory discrimination testing (MBS + LPSDT). MBS and LPSDT were performed within 4 weeks of stroke in 20 subjects who were prospectively followed for at least 2 years to identify the frequency of AP. MBS identified 10 patients as not at risk based on the finding of no aspiration on initial MBS; four of these patients developed AP (FNR = 40%). MBS + LPSDT identified five patients as not at risk based on the findings of neither aspiration nor bilateral sensory deficits; none of these patients developed AP (FNR = 0%). The combination of MBS criterion (aspiration) with the LPSDT criterion (bilateral sensory deficits) improves prognostication of outcome in dysphagic stroke patients by identifying a subgroup at high risk for developing AP (nonaspirators with bilateral deficits).
Aviv
J E
JE
Department of Otolaryngology-Head and Neck Surgery, Columbia-Presbyterian Medical Center College of Physicians and Surgeons, Columbia University, New York, New York 10032, U.S.A.
Sacco
R L
RL
Mohr
J P
JP
Thompson
J L
JL
Levin
B
B
Sunshine
S
S
Thomson
J
J
Close
L G
LG
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001466:Barium Sulfate; D016022:Case-Control Studies; D002561:Cerebrovascular Disorders / Q000150:complications* / Q000628:therapy; D003287:Contrast Media; D003679:Deglutition / Q000502:physiology*; D003680:Deglutition Disorders / Q000150:complications / Q000503:physiopathology / Q000628:therapy; D005188:False Negative Reactions; D005260:Female; D005471:Fluoroscopy; D005500:Follow-Up Studies; D005544:Forecasting; D006801:Humans; D007823:Laryngeal Nerves / Q000503:physiopathology; D007830:Larynx / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D010614:Pharynx / Q000503:physiopathology*; D011015:Pneumonia, Aspiration / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D011379:Prognosis; D011446:Prospective Studies; D012018:Reflex / Q000502:physiology; D012307:Risk Factors; D012677:Sensation / Q000502:physiology*; D012678:Sensation Disorders / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D012684:Sensory Thresholds / Q000502:physiology; D016896:Treatment Outcome
D003287:Contrast Media; D001466:Barium Sulfate