Alternative splice variants of cytokines: making a list.
The cytokine network is an extremely complicated and redundant system of mutually interdependent pleiotropic cytokines that interacts with a variety of cells, tissues and organs producing various regulatory effects, both local and systemic. Recent studies have revealed a new source of complexity in the cytokine network--alternative splicing. This minireview attempts to summarize the available data on the alternative splicing of cytokines and its regulatory significance.
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Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine, Baltimore 21201, U.S.A.
D017398:Alternative Splicing; D000818:Animals; D016207:Cytokines / Q000096:biosynthesis*; D014644:Genetic Variation; D006133:Growth Substances / Q000096:biosynthesis*; D006801:Humans; D014158:Transcription, Genetic
D016207:Cytokines; D006133:Growth Substances