title: DBT: a partial D phenotype associated with the low-incidence antigen Rh32.
abstract: Eight probands are described with a D phenotype in which a partial D antigen is associated with Rh32 antigen; three of these probands were investigated because of the anti-D in their serum. The partial D lacks epD1-epD5 and epD9 and some epD6/7 and only expresses epD8 and other parts of epD6/7. The strength of the partial D antigen varies between unrelated DBT individuals. The Rh32 antigen of the DBT cells is weaker than that of D(C)(e) cells. Tests on DBT, DFR and R0Har cells with anti-epD6/7 split these monoclonal anti-D into eight patterns of reaction. A new pattern of reactions was observed, presaging a new epitope, but this was not numbered.
authors.affiliation: Medical Research Council Blood Group Unit, London, UK.
authors.forename: M
authors.initials: M
authors.lastname: Wallace
authors.forename: C
authors.initials: C
authors.lastname: Lomas-Francis
authors.forename: E
authors.initials: E
authors.lastname: Beckers
authors.forename: M
authors.initials: M
authors.lastname: Bruce
authors.forename: G
authors.initials: G
authors.lastname: Campbell
authors.forename: S
authors.initials: S
authors.lastname: Chatfield
authors.forename: N
authors.initials: N
authors.lastname: Nagao
authors.forename: Y
authors.initials: Y
authors.lastname: Okubo
authors.forename: A
authors.initials: A
authors.lastname: Opalka
authors.forename: M
authors.initials: M
authors.lastname: Overbeeke
authors.forename: M
authors.initials: M
authors.lastname: Scott
authors.forename: D
authors.initials: D
authors.lastname: Voak
mesh_terms: D000911:Antibodies, Monoclonal; D005260:Female; D006801:Humans; D015994:Incidence; D010375:Pedigree; D010641:Phenotype; D012204:Rh-Hr Blood-Group System / Q000235:genetics*
chemical_list: D000911:Antibodies, Monoclonal; D012204:Rh-Hr Blood-Group System; C026410:Rho(D) antigen