title: Computational transient simulations with varying degree and shape of pulmonic stenosis in models of the bidirectional cavopulmonary anastomosis.
abstract: The bidirectional cavopulmonary anastomosis is a surgical technique utilized to treat severe congenital malformations of the right part of the heart. It is obtained by anastomosing the superior vena cava to the superior aspect of the undivided right pulmonary artery. Transient simulations with a three-dimensional model of the bidirectional cavopulmonary anastomosis were carried out to evaluate the haemodynamics of different types of pulmonic stenosis (shape and severity of the obstruction). Models with a tunnel-like (supravalvar) or discrete (valvar) pulmonic stenosis with different values of reduction of cross-sectional area (60 and 75%) were investigated and compared to a model without stenosis. Calculations were based on a finite element method analysis. The results showed that a tighter stenosis can lead to a blood volume flow to the left lung reaching 70% of the total pulmonary flow. Moreover, the flow fields are highly influenced by the presence and shape of the pulmonic stenosis; the most intense jets in the left pulmonary artery occur for a discrete pulmonic stenosis of 75%. The flow in the right pulmonary artery is nearly steady because it is damped down by the steady caval flow.
authors.affiliation: Dipartimento di Bioingegneria, Politecnico di Milano, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Migliavacca
authors.forename: G
authors.initials: G
authors.lastname: Dubini
authors.forename: R
authors.initials: R
authors.lastname: Pietrabissa
authors.forename: M R
authors.initials: MR
authors.lastname: de Leval
mesh_terms: D000714:Anastomosis, Surgical; D055592:Biophysical Phenomena; D001703:Biophysics; D001783:Blood Flow Velocity; D003198:Computer Simulation; D006801:Humans; D008955:Models, Cardiovascular; D011651:Pulmonary Artery / Q000503:physiopathology* / Q000601:surgery; D011652:Pulmonary Circulation; D011666:Pulmonary Valve Stenosis / Q000151:congenital / Q000503:physiopathology* / Q000601:surgery; D014683:Vena Cava, Superior / Q000503:physiopathology* / Q000601:surgery