[Evaluation of eosinophils in nasal mucus from patients with perennial allergic rhinitis during nasal provocation tests].
The purpose of this study was the evaluation of the behaviour of the eosinophils in the nasal mucous of patients with perennial allergic rhinitis in the moment of making a nasal initiation test 30 subjects were studied to which a nasal initiation test was applied with a 1:100 dilution of aqueous extracts, the samples were taken with a inferior nostril swab in basal form, in 30 minutes. Two and eight hours after the antigenic dare, the samples were tinged with the Wright technic, and the quantity of eosinophils and polymorphonuclear cells were determined. There were not adverse reaction during the procedure. The results showed eosinophils of 4.9% basal form, 13% at the 30 minutes, 19% at two hours and 28%, eight hours after the antigenic initiation, the percentage of polymorphonuclear cells was of 40.6%, 34.2%, 34.8% and 31.7% respectively. The obtained results are in accordance to the expectations in the different phases of the allergic response in rhinitis. We suggest for a correct evaluation of this nasal cytology test in patients with allergic rhinitis, the allergic response phase where the patient is, should be known.
Arzuaga Orozco
J
J
Servicio de inmunología clínica y alergia, Hospital de especialidades del Centro Médica Nacional Siglo XXI, IMSS, México.
Segura Méndez
N H
NH
Martínez Cairo-Cueto
S
S
D000293:Adolescent; D000328:Adult; D004802:Eosinophilia / Q000209:etiology / Q000473:pathology*; D004804:Eosinophils; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D009093:Mucus / Q000166:cytology*; D009297:Nasal Mucosa / Q000473:pathology*; D009299:Nasal Provocation Tests; D009504:Neutrophils; D012221:Rhinitis, Allergic, Perennial / Q000150:complications / Q000473:pathology*; D013997:Time Factors