[Hemocompatibility of various synthetic granulates].
The adherence of platelets to different polymer granulates was examined in a perfusion chamber filled with platelet-rich plasma. The surface area of each of the granulates was of a standardised size. The results were compared with those found for a non-thrombogenic and a highly thrombogenic foreign-body surface. The three polymers examined-Cryolite, Styrolux and Zylar-must be considered non-thrombogenic. Platelet adherence to these substances is significantly less (3%) than that to a highly thrombogenic surface such as glass (95%). The three materials did not differ in terms of platelet adherence, and would appear to be suitable potential materials for use in cell separators.
Jung
F
F
Abteilung für Klinische Hämostaseologie und Transfusionsmedizin, Universität des Saarlandes, Homburg/Saar.
Mrowietz
C
C
Seyfert
U T
UT
Franke
R P
RP
D001672:Biocompatible Materials; D002469:Cell Separation / Q000295:instrumentation*; D006801:Humans; D008422:Materials Testing; D010316:Particle Size; D010973:Platelet Adhesiveness / Q000502:physiology*; D010983:Plateletpheresis / Q000295:instrumentation*; D011108:Polymers; D013927:Thrombosis / Q000097:blood
D001672:Biocompatible Materials; D011108:Polymers