Cotranslational disassembly of flock house virus in a cell-free system.
Intact, purified particles of the nodaviruses flock house virus and nodamura virus that were either transfected into cells that were resistant to infection or introduced into in vitro translation systems directed the synthesis of viral proteins. We infer that direct interaction of these nodavirus particles with cytoplasmic components mediated virion disassembly that resulted in release of the viral RNA.
Hiscox
J A
JA
Department of Microbiology, University of Alabama at Birmingham, 35294-2170, USA.
Ball
L A
LA
D000818:Animals; D002460:Cell Line; D002474:Cell-Free System; D006224:Cricetinae; D007304:Insect Viruses / Q000502:physiology*; D014176:Protein Biosynthesis; D012328:RNA Viruses / Q000502:physiology*; D012367:RNA, Viral / Q000378:metabolism*; D014162:Transfection; D014764:Viral Proteins / Q000096:biosynthesis; D014771:Virion / Q000502:physiology; D014779:Virus Replication
D012367:RNA, Viral; D014764:Viral Proteins