Complete remission in three patients with acute myeloblastic leukemia by administration of G-CSF without antileukemic agents.
We describe 3 patients with acute myeloblastic leukemia (AML), who received rhG-CSF for infections such as pneumonia or for prophylaxis of infection, and who achieved complete remission. They had not received any antileukemic therapy before or during the administration of rhG-CSF. These findings suggest the possibility that complete remission can be brought about by G-CSF itself in some patients with AML.
Takahashi
M
M
First Department of Internal Medicine, School of Medicine, Niigata University, Japan. matak@clg.niigata-u.ac.jp
Koike
T
T
Aizawa
Y
Y
Kashimura
M
M
Hayatsu
K
K
Nagai
K
K
Abe
A
A
Urushiyama
M
M
Yagisawa
K
K
D000368:Aged; D001424:Bacterial Infections / Q000209:etiology / Q000517:prevention & control; D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011994:Recombinant Proteins / Q000627:therapeutic use; D012074:Remission Induction
D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor