Malignant endovascular papillary angioendothelioma (Dabska tumor) arising within a deep intramuscular hemangioma.
We report a rare malignant endovascular papillary angioendothelioma (Dabska tumor) arising within the deep periosteal soft tissue of the ulna of an 8-year-old girl. To our knowledge, this is the first report of a Dabska tumor of deep soft tissue that did not extend down from the dermis. This Dabska tumor appears to be a focal change within a larger, well-defined, cavernous hemangioma of deep muscle. We suggest that this represents secondary neoplastic progression of an existing benign lesion, a common phenomenon among vascular tumors. A review of the family of "hobnailed" endothelial cell lesions to which Dabska tumor belongs is presented.
Argani
P
P
Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Athanasian
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E
D002648:Child; D004730:Endothelium, Vascular / Q000473:pathology; D005260:Female; D005542:Forearm / Q000000981:diagnostic imaging / Q000473:pathology; D006390:Hemangioendothelioma / Q000150:complications / Q000473:pathology*; D006392:Hemangioma, Cavernous / Q000150:complications / Q000473:pathology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D019042:Muscle Neoplasms / Q000473:pathology*; D016609:Neoplasms, Second Primary / Q000473:pathology*; D011859:Radiography; D019043:Vascular Neoplasms / Q000150:complications / Q000473:pathology*