title: Recurrent toxoplasmic retinochoroiditis. Significance of perilesional satellite dark dots seen by indocyanine green angiography.
abstract: OBJECTIVE
  To suggest an explanation for the satellite dark dots seen by indocyanine green angiography (ICGA) around the main focus of a toxoplasmic retinochoroiditis.
  
  
  METHODS
  The authors analysed the evolution of ICG satellite dark dots in two cases of recurrent toxoplasmic retinochoroiditis receiving anti-toxoplasmic treatment not including corticosteroids.
  
  
  RESULTS
  Both patients had a recurrence on the peripheral aspect of scars from previous retinochoroiditis and were treated with pyrimethamine (50 mg/day) and sulfadiazine (4 g/day) for seven weeks. Resolution of satellite ICG dark dots was observed in both cases on the follow-up ICG angiogram performed at the end of treatment.
  
  
  CONCLUSIONS
  Resolution of ICG satellite dark dots after anti-toxoplasmic treatment not including corticosteroids tends to indicate that there is probably an infectious component in these hypofluorescent dots and that they probably do not represent a purely inflammatory perilesional reaction.
authors.affiliation: Department of Ophthalmology, Hôpital Jules Gonin, University of Lausanne, Switzerland.
authors.forename: O
authors.initials: O
authors.lastname: Bernasconi
authors.forename: C
authors.initials: C
authors.lastname: Auer
authors.forename: C P
authors.initials: CP
authors.lastname: Herbort
mesh_terms: D000328:Adult; D000792:Angiography; D000890:Anti-Infective Agents / Q000627:therapeutic use; D002825:Chorioretinitis / Q000188:drug therapy / Q000473:pathology*; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D011739:Pyrimethamine / Q000627:therapeutic use; D012008:Recurrence; D013411:Sulfadiazine / Q000627:therapeutic use; D014126:Toxoplasmosis, Ocular / Q000188:drug therapy / Q000473:pathology*; D014792:Visual Acuity
chemical_list: D000890:Anti-Infective Agents; D004396:Coloring Agents; D013411:Sulfadiazine; D007208:Indocyanine Green; D011739:Pyrimethamine