title: [Regularities in the spread of hepatitis C virus and its genotypes in Russian and countries within the former USSR].
abstract: The incidence of markers of hepatitis C virus (HCV in the blood of 4216 normal subjects living in the European Russia (Northern, North-Western, Central, Central Chernozem, Volga-Vyatka, Volga, and North Caucasian regions), in the Urals, in Siberia (Eastern Siberian region), in the Far East, and in Monogolia is assessed. The incidence of antibodies to HCV varied from 0.7% in the Central region to 3.8% in the Central Chernozem and 10.7% in Mongolia. HCV genotyping (identification of 1a, 1b, 2a, 2b, and 3a genotypes) was performed using 469 RNA of HCV-positive sera of donors and patients collected in Russia, Moldova, Turkmenistan, and Mongolia. The 1b genotype predominated everywhere (68.9%), its incidence being the highest in Moldova (96%). Unclassifiable variants of HCV were found in 28 (6%) of sera. The regularities of HCV genotypes circulation in the European Russia were the same as in other European countries, whereas their prevalence in Eastern Russia was rather like that in China or Japan. The prevalence of genotypes did not depend on the clinical manifestations of diseases caused by HCV.
authors.forename: D K
authors.initials: DK
authors.lastname: L'vov
authors.forename: E I
authors.initials: EI
authors.lastname: Samokhvalov
authors.forename: S
authors.initials: S
authors.lastname: Mishiro
authors.forename: F
authors.initials: F
authors.lastname: Tsuda
authors.forename: N A
authors.initials: NA
authors.lastname: Selivanov
authors.forename: H
authors.initials: H
authors.lastname: Okamoto
authors.forename: V M
authors.initials: VM
authors.lastname: Stakhanova
authors.forename: V L
authors.initials: VL
authors.lastname: Gromashevskiĭ
authors.forename: V A
authors.initials: VA
authors.lastname: Aristova
authors.forename: N V
authors.initials: NV
authors.lastname: Doroshenko
authors.forename: T L
authors.initials: TL
authors.lastname: Iashina
authors.forename: S N
authors.initials: SN
authors.lastname: Kuzin
authors.forename: I A
authors.initials: IA
authors.lastname: Suetina
authors.forename: D S
authors.initials: DS
authors.lastname: Lobanov
authors.forename: P G
authors.initials: PG
authors.lastname: Deriabin
authors.forename: L A
authors.initials: LA
authors.lastname: Ruzaeva
authors.forename: V N
authors.initials: VN
authors.lastname: Bezgodov
authors.forename: V I
authors.initials: VI
authors.lastname: Frizen
authors.forename: L A
authors.initials: LA
authors.lastname: Firsova
authors.forename: L I
authors.initials: LI
authors.lastname: Firsova
authors.forename: B B
authors.initials: BB
authors.lastname: Darizhapov
authors.forename: S D
authors.initials: SD
authors.lastname: L'vov
authors.forename: V N
authors.initials: VN
authors.lastname: Smirnov
authors.forename: V E
authors.initials: VE
authors.lastname: Lisitsina
authors.forename: I A
authors.initials: IA
authors.lastname: Shchukina
mesh_terms: D000293:Adolescent; D000328:Adult; D017517:Commonwealth of Independent States / Q000453:epidemiology; D005260:Female; D005838:Genotype; D016174:Hepacivirus / Q000145:classification / Q000235:genetics*; D006526:Hepatitis C / Q000453:epidemiology* / Q000821:virology; D006801:Humans; D015995:Prevalence; D013045:Species Specificity