Mechanism of anti-proliferative action of eicosapentaenoic acid (EPA) in vascular cell growth: its effect on signal transduction system.
Terano
T
T
2nd Department of Internal Medicine, Chiba University School of Medicine, Japan.
Hirai
A
A
Shiina
T
T
Tamura
Y
Y
Saitoh
Y
Y
D000284:Administration, Oral; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use; D016718:Arachidonic Acid / Q000378:metabolism; D001161:Arteriosclerosis / Q000517:prevention & control; D001162:Arteriosclerosis Obliterans / Q000188:drug therapy; D001241:Aspirin / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D002986:Clinical Trials as Topic; D015777:Eicosanoids / Q000096:biosynthesis; D015118:Eicosapentaenoic Acid / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D011464:Epoprostenol / Q000096:biosynthesis; D005343:Fibrinolytic Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D006131:Growth Inhibitors / Q000494:pharmacology*; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D000960:Hypolipidemic Agents / Q000494:pharmacology; D009131:Muscle, Smooth, Vascular / Q000166:cytology / Q000187:drug effects*; D010974:Platelet Aggregation / Q000187:drug effects; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology; D051381:Rats; D015398:Signal Transduction / Q000187:drug effects*; D019851:Thrombophilia / Q000097:blood / Q000188:drug therapy; D013927:Thrombosis / Q000517:prevention & control; D013928:Thromboxane A2 / Q000096:biosynthesis
D000894:Anti-Inflammatory Agents, Non-Steroidal; D015777:Eicosanoids; D005343:Fibrinolytic Agents; D006131:Growth Inhibitors; D000960:Hypolipidemic Agents; D010975:Platelet Aggregation Inhibitors; D016718:Arachidonic Acid; D013928:Thromboxane A2; D015118:Eicosapentaenoic Acid; D011464:Epoprostenol; D001241:Aspirin