Changes in umbilical artery, middle cerebral artery, and aorta blood flow Doppler waveform pulsatility indices after funisocentesis.
This study evaluates the effect of funisocentesis on umbilical artery, fetal cerebral artery, and aortic circulation. The pulsatility index in the umbilical artery, fetal middle cerebral artery, and descending aorta was measured by pulsed Doppler ultrasonography before and after 41 diagnostic funisocenteses. Percutaneous umbilical artery blood sampling was associated with a significant decrease in umbilical artery pulsatility index (mean -0.132, standard deviation 0.259, P = 0.002) and in middle cerebral artery pulsatility index (mean -0.143, standard deviation 0.260, P = 0.001). The decline in resistance to flow of the umbilical artery (r = 0.340, P = 0.029) and middle cerebral artery (r = 0.457, P = 0.002) was correlated with gestational age at sampling. These findings suggest that alterations in the waveforms from both the umbilical and the fetal cerebral circulations can be induced by fetal blood sampling.
Chitrit
Y
Y
Department of Obstetrics and Gynecology, Centre Hospitalier, Général R. Ballanger, Aulnysous-Bois, France.
Caubel
P
P
Boulanger
M C
MC
Schwinte
A L
AL
Baledent
F
F
Lusina
D
D
Ter Sakarian
M
M
D001013:Aorta, Thoracic / Q000000981:diagnostic imaging* / Q000196:embryology; D002536:Cerebral Arteries / Q000000981:diagnostic imaging* / Q000196:embryology; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D006340:Heart Rate, Fetal; D006801:Humans; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000009:adverse effects*; D011673:Pulsatile Flow; D012039:Regional Blood Flow; D012044:Regression Analysis; D018617:Ultrasonography, Doppler, Pulsed; D016216:Ultrasonography, Prenatal; D014469:Umbilical Arteries / Q000000981:diagnostic imaging*; D014655:Vascular Resistance