title: Secretory meningioma with severe perifocal edema--case report.
abstract: An 82-year-old male presented with a small parasagittal meningioma associated with disproportionately severe perifocal edema. Histological examination including immunohistochemical staining and electron microscopy resulted in a diagnosis of secretory meningioma. In addition to tumor size, the edema could not be explained by location, growth rate, vascular involvement, or other factors. We conclude that secretory meningiomas may possess an innate ability to cause brain edema.
authors.affiliation: Department of Neurosurgery, Self Defense Forces Central Hospital, Tokyo, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Tsuzuki
authors.forename: H
authors.initials: H
authors.lastname: Nakau
authors.forename: M
authors.initials: M
authors.lastname: Sugaya
authors.forename: K
authors.initials: K
authors.lastname: Hashizume
authors.forename: S
authors.initials: S
authors.lastname: Matsukuma
authors.forename: R
authors.initials: R
authors.lastname: Wada
authors.forename: N
authors.initials: N
authors.lastname: Kuwabara
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001921:Brain / Q000473:pathology / Q000601:surgery; D001929:Brain Edema / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery; D003399:Craniotomy; D003594:Cytoplasmic Granules / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000378:metabolism* / Q000473:pathology / Q000601:surgery; D008579:Meningioma / Q000378:metabolism* / Q000473:pathology / Q000601:surgery; D008854:Microscopy, Electron; D014057:Tomography, X-Ray Computed