title: Manauealides, some of the causative agents of a red alga Gracilaria coronopifolia poisoning in Hawaii.
abstract: Manauealides A-C (1-3), compounds related to debromoaplysiatoxin (5), were isolated and characterized from a red alga Gracilaria coronopifolia. Compounds 1 and 2 are presumed to be the causative toxins of G. coronopifolia food poisoning in Hawaii. Manauealide A (1) and C (3) are new macrolides, whereas manauealide B (2) is a known semisynthetic product of 5.
authors.affiliation: Suntory Institute for Bioorganic Research, Osaka, Japan. LEE05540@niftyserve.or.jp
authors.forename: H
authors.initials: H
authors.lastname: Nagai
authors.forename: T
authors.initials: T
authors.lastname: Yasumoto
authors.forename: Y
authors.initials: Y
authors.lastname: Hokama
mesh_terms: D002240:Carbohydrate Sequence; D002851:Chromatography, High Pressure Liquid; D005517:Foodborne Diseases / Q000503:physiopathology*; D006254:Hawaii; D008235:Lyngbya Toxins / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity; D018942:Macrolides / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity; D009682:Magnetic Resonance Spectroscopy; D008387:Marine Toxins / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity; D008969:Molecular Sequence Data; D000461:Rhodophyta / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013056:Spectrophotometry, Ultraviolet
chemical_list: D008235:Lyngbya Toxins; D018942:Macrolides; D008387:Marine Toxins; C108754:manauealide A; C108755:manauealide B; C108756:manauealide C