A cell-based assay for brevetoxins, saxitoxins, and ciguatoxins using a stably expressed c-fos-luciferase reporter gene.
Fairey
E R
ER
Marine Biotoxins Program, NOAA Southeast Fisheries Science Center Charleston Laboratory, Medical University of South Carolina, Charleston 29412, USA.
Edmunds
J S
JS
Ramsdell
J S
JS
D000818:Animals; D001681:Biological Assay / Q000379:methods*; D002454:Cell Differentiation; D002460:Cell Line; D002922:Ciguatoxins / Q000032:analysis* / Q000633:toxicity; D005069:Evaluation Studies as Topic; D017930:Genes, Reporter; D016762:Genes, fos; D008156:Luciferases / Q000235:genetics; D008387:Marine Toxins / Q000032:analysis* / Q000633:toxicity; D051379:Mice; D009498:Neurotoxins / Q000032:analysis / Q000633:toxicity; D035964:Oxocins; D012530:Saxitoxin / Q000032:analysis* / Q000633:toxicity; D015222:Sodium Channels / Q000187:drug effects; D000095702:Polyether Toxins
D002922:Ciguatoxins; D008156:Luciferases; D008387:Marine Toxins; D009498:Neurotoxins; D035964:Oxocins; D012530:Saxitoxin; D015222:Sodium Channels; C053342:brevetoxin; D000095702:Polyether Toxins