Adjuvant chemotherapy for testicular cancer.
Two treatment options cure nearly all patients with pathologic stage II testicular nonseminomatous germ cell tumor following a retroperitoneal lymph node dissection. These are (1) two cycles of adjuvant etoposide plus cisplatin (with or without bleomycin) chemotherapy and (2) close surveillance with chemotherapy reserved for relapse. The decision to choose one of these options is dependent on the extent of tumor involvement at surgery and patient compliance.
Xiao
H
H
Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
Sheinfeld
J
J
Motzer
R J
RJ
D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage; D000970:Antineoplastic Agents / Q000008:administration & dosage; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D005500:Follow-Up Studies; D018237:Germinoma / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy; D009367:Neoplasm Staging; D010349:Patient Compliance; D013736:Testicular Neoplasms / Q000188:drug therapy / Q000601:surgery*
D000903:Antibiotics, Antineoplastic; D000970:Antineoplastic Agents; D000972:Antineoplastic Agents, Phytogenic; D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin