title: Role of 12-lipoxygenase and protein kinase C in modulating the activation state of the integrin alpha IIb beta 3 on human tumor cells.
authors.affiliation: Department of Pathology, Wayne State University, Detroit, Michigan 48202, USA.
authors.forename: M
authors.initials: M
authors.lastname: Trikha
authors.forename: K V
authors.initials: KV
authors.lastname: Honn
mesh_terms: D019377:12-Hydroxy-5,8,10,14-eicosatetraenoic Acid / Q000502:physiology; D001092:Arachidonate 12-Lipoxygenase / Q000502:physiology*; D002448:Cell Adhesion / Q000187:drug effects; D002465:Cell Movement; D018450:Disease Progression; D004789:Enzyme Activation; D005109:Extracellular Matrix / Q000378:metabolism; D006801:Humans; D008954:Models, Biological; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis / Q000503:physiopathology*; D009363:Neoplasm Proteins / Q000502:physiology*; D019039:Platelet Glycoprotein GPIIb-IIIa Complex / Q000378:metabolism*; D011493:Protein Kinase C / Q000502:physiology*; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D014407:Tumor Cells, Cultured
chemical_list: D009363:Neoplasm Proteins; D019039:Platelet Glycoprotein GPIIb-IIIa Complex; D019377:12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; D001092:Arachidonate 12-Lipoxygenase; D011493:Protein Kinase C; D013755:Tetradecanoylphorbol Acetate