title: Outbreak of adenovirus 35 pneumonia among adult residents and staff of a chronic care psychiatric facility.
abstract: Outbreaks of acute respiratory disease caused by adenovirus are rarely documented in civilian populations, and adenovirus 35 is an uncommon serotype best recognized as a cause of serious disease in immunocompromised patients. An outbreak of adenovirus 35 pneumonia among residents and staff of a chronic care psychiatric facility was investigated. Fourteen (26%) of 53 residents and 4 (2%) of approximately 200 staff had radiographically confirmed pneumonia. Thirteen (93%) of 14 residents with pneumonia were hospitalized, 5 (36%) required mechanical ventilation, and 1 (7%) died. One staff member was hospitalized. Adenovirus infection was diagnosed in 17 (94%) persons with pneumonia by culture or serology and was confirmed as adenovirus 35 infection in 8 persons. Residents with pneumonia had resided at the facility longer than other residents. Chronic illness was not a risk factor for severe disease. Crowding and poor hygienic behaviors probably facilitated transmission among residents.
authors.affiliation: Division of Field Epidemiology, Epidemiology Program Office, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA.
authors.forename: M P
authors.initials: MP
authors.lastname: Sanchez
authors.forename: D D
authors.initials: DD
authors.lastname: Erdman
authors.forename: T J
authors.initials: TJ
authors.lastname: Torok
authors.forename: C J
authors.initials: CJ
authors.lastname: Freeman
authors.forename: B T
authors.initials: BT
authors.lastname: Matyas
mesh_terms: D000257:Adenoviridae Infections / Q000453:epidemiology* / Q000821:virology; D000260:Adenoviruses, Human / Q000145:classification; D000328:Adult; D003428:Cross Infection / Q000453:epidemiology* / Q000821:virology; D004196:Disease Outbreaks; D005260:Female; D006778:Hospitals, Psychiatric; D006801:Humans; D008297:Male; D008875:Middle Aged; D010564:Personnel, Hospital; D011024:Pneumonia, Viral / Q000453:epidemiology*; D012307:Risk Factors; D012703:Serotyping; D014407:Tumor Cells, Cultured