[The interrelation of changes in the upper and lower respiratory tracts in chronic bronchitis patients with different diseases of the nose and paranasal sinuses].
The examination covered 44 patients (16 males and 28 females) with chronic bronchitis (CB) associated with diseases of the nose and paranasal sinuses. Most of the patients (63.6%) had allergic rhinosinusopathy (ARSP). The kind of nasal and sinus affection varied with CB form (catarrhal or purulent). Aggravation of ENT disorders provoked deterioration of external respiration. Bronchial and maxillary mucosa showed identical changes in CB patients with purulent affection of the paranasal sinuses. Cytological examinations of the smear, lavage and sputum discovered a tendency to increased count of eosinophil leukocytes in all the samples from CB plus ARSP patients. On cytograms of bronchial lavage from patients with polypous-purulent ARSP there were also low counts of macrophages and lymphocytes. This is likely to reflect pronounced defects of local defense of the bronchi promoting progressive inflammatory and allergic processes.
Ovcharenko
S I
SI
Chichkova
N V
NV
Makolkin
V I
VI
D000293:Adolescent; D000328:Adult; D001991:Bronchitis / Q000175:diagnosis* / Q000503:physiopathology; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology / Q000382:microbiology; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009297:Nasal Mucosa / Q000166:cytology / Q000378:metabolism; D009668:Nose Diseases / Q000175:diagnosis* / Q000503:physiopathology; D010254:Paranasal Sinus Diseases / Q000175:diagnosis* / Q000503:physiopathology; D012137:Respiratory System / Q000503:physiopathology*; D013147:Spirometry; D013183:Sputum / Q000166:cytology / Q000382:microbiology