title: Bromism: intoxication from a rare anticonvulsant therapy.
abstract: Bromide, the first effective therapy for epilepsy, is not commonly prescribed today but has been advocated by some pediatric neurologists for the treatment of intractable seizures in children. We report a 17-year-old female patient with intractable epilepsy who insidiously developed bromism while on treatment with triple bromide elixir. We review the clinical presentation, diagnosis, pathophysiology, and management of bromism.
authors.affiliation: Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, USA.
authors.forename: L P
authors.initials: LP
authors.lastname: James
authors.forename: H C
authors.initials: HC
authors.lastname: Farrar
authors.forename: M L
authors.initials: ML
authors.lastname: Griebel
authors.forename: S R
authors.initials: SR
authors.lastname: Bates
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000009:adverse effects*; D001965:Bromides / Q000009:adverse effects*; D003221:Confusion / Q000139:chemically induced; D004827:Epilepsy / Q000188:drug therapy; D005260:Female; D006801:Humans; D007508:Irritable Mood / Q000187:drug effects; D011041:Poisoning / Q000628:therapy; D013064:Speech Disorders / Q000139:chemically induced
chemical_list: D000927:Anticonvulsants; D001965:Bromides