title: Antiphospholipid antibodies: standardization and testing.
abstract: A phenomenon originally scorned as a laboratory nuisance has turned out to be an important cause of thromboembolism, fetal death, and other forms of human disease. Investigations of this inaptly named "lupus anticoagulant" has led to the discovery of at least two distinct types of autoimmune antibodies. In spite of recent discoveries regarding the pathophysiology of these antibodies, their clinical significance is still controversial.
authors.affiliation: Department of Pathology, Medical College of Virginia, Richmond, USA.
authors.forename: R S
authors.initials: RS
authors.lastname: Riley
authors.forename: J
authors.initials: J
authors.lastname: Friedline
authors.forename: J S
authors.initials: JS
authors.lastname: Rogers
mesh_terms: D017152:Antibodies, Antiphospholipid / Q000032:analysis* / Q000276:immunology; D016736:Antiphospholipid Syndrome / Q000276:immunology*; D001780:Blood Coagulation Tests / Q000592:standards*; D005260:Female; D006801:Humans; D011247:Pregnancy; D011786:Quality Control; D009626:Terminology as Topic
chemical_list: D017152:Antibodies, Antiphospholipid