title: Long-term follow-up of corridor operation for lone atrial fibrillation: evidence for progression of disease?
abstract: BACKGROUND
  Currently, surgery- and catheter-mediated ablation is applied when drug refractoriness of atrial fibrillation is evident, although little is known about the long-term incidence of new atrial arrhythmia and the preservation of sinus node function.
  
  
  RESULTS
  To address this issue, 30 patients with successful corridor surgery for lone paroxysmal atrial fibrillation and normal preoperative sinus node function were followed in a single outpatient department. Five years after surgery, the actuarial proportion of patients with recurrence of atrial fibrillation arising in the corridor was 8% +/- 5%, with new atrial arrhythmias consisting of atrial flutter and atrial tachycardia in the corridor 27% +/- 8%, and with incompetent sinus node requiring pacing therapy 13% +/- 6%. Right atrial transport was preserved in 69% of the patients without recurrence of atrial fibrillation and normal sinus node function. Stroke was documented in two patients.
  
  
  CONCLUSIONS
  Corridor surgery for atrial fibrillation is a transient or palliative treatment instead of a definitive therapy for drug refractory atrial fibrillation. This observation strongly affects patient selection for this intervention and constitutes a word of caution for other, nonpharmacologic interventions for drug refractory atrial fibrillation.
authors.affiliation: Department of Cardiology, St. Antonius Hospital, Nieuwegein, The Netherlands.
authors.forename: N M
authors.initials: NM
authors.lastname: van Hemel
authors.forename: J J
authors.initials: JJ
authors.lastname: Defauw
authors.forename: G M
authors.initials: GM
authors.lastname: Guiraudon
authors.forename: J C
authors.initials: JC
authors.lastname: Kelder
authors.forename: E R
authors.initials: ER
authors.lastname: Jessurun
authors.forename: J M
authors.initials: JM
authors.lastname: Ernst
mesh_terms: D000328:Adult; D001145:Arrhythmias, Cardiac / Q000503:physiopathology; D001281:Atrial Fibrillation / Q000150:complications* / Q000503:physiopathology / Q000601:surgery*; D016280:Atrial Function, Right / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010138:Pacemaker, Artificial; D011183:Postoperative Complications / Q000209:etiology* / Q000503:physiopathology; D011446:Prospective Studies; D012008:Recurrence; D012849:Sinoatrial Node / Q000503:physiopathology; D013923:Thromboembolism / Q000503:physiopathology; D013997:Time Factors