title: Thyroid function in attention deficit and hyperactivity disorder.
abstract: In view of the recent conflicting findings regarding the causative role of thyroid abnormalities in attention deficit hyperactivity disorder (ADHD), we performed a replication study to clarify the issue and establish clinical guidelines. Thyroid tests were performed in 43 ADHD children and 28 age- and gender-matched controls. Sixteen ADHD children showed total triiodothyronine (TT3) levels which were slightly above the upper limit of normal, but no significant difference in TT3 values was noted between the ADHD and the control groups. Moreover, none of the ADHD subjects had abnormal levels of total thyroxine, free thyroxine, thyroid stimulating hormone or total triiodothyronine reuptake. The present study supplies additional evidence for the lack of an association between thyroid function and ADHD, and counters the suggestion that thyroid function be routinely screened for in ADHD children.
authors.affiliation: Tel Aviv Community Mental Health Center, Tel Aviv University, Israel.
authors.forename: P
authors.initials: P
authors.lastname: Toren
authors.forename: A
authors.initials: A
authors.lastname: Karasik
authors.forename: S
authors.initials: S
authors.lastname: Eldar
authors.forename: L
authors.initials: L
authors.lastname: Wolmer
authors.forename: I
authors.initials: I
authors.lastname: Shimon
authors.forename: R
authors.initials: R
authors.lastname: Weitz
authors.forename: D
authors.initials: D
authors.lastname: Inbar
authors.forename: S
authors.initials: S
authors.lastname: Koren
authors.forename: C
authors.initials: C
authors.lastname: Pariente
authors.forename: A
authors.initials: A
authors.lastname: Reiss
authors.forename: R
authors.initials: R
authors.lastname: Weizman
authors.forename: N
authors.initials: N
authors.lastname: Laor
mesh_terms: D000293:Adolescent; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D012016:Reference Values; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000503:physiopathology; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
chemical_list: D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine