Reversible segmental left-ventricular dysfunction caused by accidental administration of sympathomimetic drug in human.
A inadvertently administrated high dose of sympathomimetic drug induced cardiogenic shock manifestations in a previously healthy woman. This state was characterized by EKG subendocardial injury, serum cardiac enzymes elevation, extensive regional left ventricular wall motion abnormalities on echocardiogram. Therapeutics included oxygen, systemic vasodilators and diuretics. Clinical recovery occurred over a four days period and parallels the normalization of echocardiogram and EKG alterations.
Simões
M V
MV
Department of Internal Medicine, Medical School of Ribeirão Preto, University of São Paulo, Brazil.
Maciel
B C
BC
Marin-Neto
J A
JA
D000328:Adult; D005260:Female; D006801:Humans; D007022:Hypotension / Q000188:drug therapy*; D008508:Medication Errors; D008680:Metaraminol / Q000008:administration & dosage / Q000009:adverse effects*; D012770:Shock, Cardiogenic / Q000139:chemically induced; D013566:Sympathomimetics / Q000008:administration & dosage / Q000009:adverse effects*; D014463:Ultrasonography; D018487:Ventricular Dysfunction, Left / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy
D013566:Sympathomimetics; D008680:Metaraminol