Applications of computer assisted quantum pharmacology calculations in devising anticonvulsant rational polypharmacy strategies.
Weaver
D F
DF
Department of Neurology, Queen's University, Kingston, Ontario, Canada.
D000927:Anticonvulsants / Q000008:administration & dosage* / Q000009:adverse effects / Q000493:pharmacokinetics; D001921:Brain / Q000187:drug effects* / Q000503:physiopathology; D001931:Brain Mapping; D003198:Computer Simulation; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D004360:Drug Therapy, Computer-Assisted; D004569:Electroencephalography / Q000187:drug effects; D004827:Epilepsy / Q000188:drug therapy* / Q000503:physiopathology; D006801:Humans; D008564:Membrane Potentials / Q000187:drug effects / Q000502:physiology; D009474:Neurons / Q000187:drug effects / Q000502:physiology; D011789:Quantum Theory; D017981:Receptors, Neurotransmitter / Q000187:drug effects / Q000502:physiology; D013329:Structure-Activity Relationship; D009435:Synaptic Transmission / Q000187:drug effects* / Q000502:physiology; D016896:Treatment Outcome
D000927:Anticonvulsants; D017981:Receptors, Neurotransmitter