title: [Rare initial manifestation and differential diagnosis of primary sclerosing cholangitis].
abstract: BACKGROUND
  Primary sclerosing cholangitis is most often diagnosed in middle-aged men who are suffering from inflammatory bowel diseases.
  
  
  METHODS
  A young, previously healthy woman presents with icterus of acute onset, high transaminases and positive hepatitis B virus serology. Ultrasound and nuclear magnetic resonance images demonstrate multiple liver tumors. After acute viral hepatitis as well as primary or secondary malignant liver tumors have been excluded as underlying diseases, diagnosis of primary sclerosing cholangitis is made.
  
  
  CONCLUSIONS
  Differential diagnosis of primary sclerosing cholangitis should also be considered in cases with untypical primary presentation.
authors.affiliation: Abteilung Gastroenterologie und Hepatologie, Zentrum Innere Medizin und Dermatologie, Medizinische Hochschule Hannover.
authors.forename: B
authors.initials: B
authors.lastname: Rehermann
authors.forename: K
authors.initials: K
authors.lastname: Klugewitz
authors.forename: U
authors.initials: U
authors.lastname: Seifert
authors.forename: K H
authors.initials: KH
authors.lastname: Böker
authors.forename: S
authors.initials: S
authors.lastname: Wagner
authors.forename: M P
authors.initials: MP
authors.lastname: Manns
mesh_terms: D000208:Acute Disease; D000328:Adult; D001323:Autoantibodies / Q000097:blood; D015209:Cholangitis, Sclerosing / Q000175:diagnosis*; D003937:Diagnosis, Differential; D005260:Female; D006509:Hepatitis B / Q000175:diagnosis*; D006801:Humans; D008099:Liver / Q000473:pathology; D008111:Liver Function Tests; D008279:Magnetic Resonance Imaging
chemical_list: D001323:Autoantibodies