[Study about development of extracapillary blood flow type oxygenator--comparison with HF-4000, Capiox II, and Silox].
Results about comparison of new extracapillary blood flow type polypropylene hollow fiber oxygenator (PHO) with HF-4000, Capiox II and Silox for effects on blood components, hemolysis, immunoglobulin and high molecular weight proteins, such as complements: 1) Platelet protection was about equal. Silox was best in leucocyte protection. 2) PHO was superior to HF-4000. The extracapillary type was better for hemolysis. 3) Silox was best in immunoglobulin protection. Effect on C3 and C4 was equal, and Silox was best in protection of CH50. Slight differences were caused by silicone membrane, not caused by blood flow type. 4) PHO was superior to HF-4000 (commercial extracapillary type), and almost equal to Capiox II (intracapillary type).
Ishii
Y
Y
Ohmori
K
K
Sezai
Y
Y
D000328:Adult; D000368:Aged; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D015941:Complement Hemolytic Activity Assay; D005069:Evaluation Studies as Topic; D006454:Hemoglobins / Q000032:analysis; D006461:Hemolysis; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007958:Leukocyte Count; D008875:Middle Aged; D010106:Oxygenators / Q000009:adverse effects / Q000592:standards*
D003176:Complement C3; D003181:Complement C4; D006454:Hemoglobins; D007074:Immunoglobulin G; D007075:Immunoglobulin M