title: Paget's disease of the sternum simulating an ectopic adenoma on parathyroid scintigraphy.
abstract: The authors present the case of a patient with recurrent hyperparathyroidism who was shown on thallium-technetium subtraction scintigraphy, ultrasound, and magnetic resonance imaging to have recurrent parathyroid tissue in the right side of the neck. The thallium scan also showed intense uptake centrally in the chest, mimicking an intrathoracic adenoma. This was subsequently shown on plain films and a radionuclide bone scan to be due to Paget's disease of the sternum. This case illustrates the value of a combined imaging strategy in preventing an unnecessary thoracotomy after a false-positive nuclear medicine scan.
authors.affiliation: Department of Radiology, University Hospital Of Wales NHS Healthcare Trust, Heath Park, Cardiff, United Kingdom.
authors.forename: R
authors.initials: R
authors.lastname: Seymour
authors.forename: J
authors.initials: J
authors.lastname: Rees
authors.forename: A K
authors.initials: AK
authors.lastname: Sharma
authors.forename: M H
authors.initials: MH
authors.lastname: Wheeler
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging*; D000368:Aged; D002828:Choristoma / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000175:diagnosis / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D009333:Neck / Q000000981:diagnostic imaging*; D010001:Osteitis Deformans / Q000000981:diagnostic imaging*; D010280:Parathyroid Glands / Q000000981:diagnostic imaging; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals; D012008:Recurrence; D013249:Sternum / Q000000981:diagnostic imaging*; D013382:Subtraction Technique; D013669:Technetium Tc 99m Medronate; D013794:Thallium Radioisotopes; D013896:Thoracic Diseases / Q000000981:diagnostic imaging; D015899:Tomography, Emission-Computed, Single-Photon; D014463:Ultrasonography
chemical_list: D019275:Radiopharmaceuticals; D013794:Thallium Radioisotopes; D013669:Technetium Tc 99m Medronate