Oesophageal involvement in cicatricial pemphigoid.
Four cases of cicatricial pemphigoid complicated by oesophageal involvement are presented. All patients suffered dysphagia but repeated radiological studies were required for confirmation of oesophageal ulceration, webs and strictures. A combination of systemic drug therapy and oesophageal dilatation were necessary for the suppression of symptoms. The clinical and immunopathological features, management and complications of oesophageal involvement in cicatricial pemphigoid are discussed. Dermatologists should be aware of these features and make regular inquiries about swallowing difficulties in patients with cicatricial pemphigoid to guide appropriate investigations and treatment.
Warren
L J
LJ
Dermatology Department, Amersham Hospital, United Kingdom.
Wojnarowska
F
F
Wilkinson
J D
JD
D000368:Aged; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D004106:Dilatation; D018572:Disease-Free Survival; D004940:Esophageal Stenosis / Q000209:etiology* / Q000473:pathology* / Q000601:surgery; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D010390:Pemphigoid, Benign Mucous Membrane / Q000150:complications* / Q000473:pathology* / Q000601:surgery