title: A computer program for correlating dental plaque pH values, cH+, plaque titration, critical pH, resting pH and the solubility of enamel apatite.
abstract: A computer program was written in Visual Basic (Microsoft) to calculate (a) the area between a plaque pH curve (as seen after a sucrose rinse) and either a resting pH (around pH 7) or a critical pH value (around 5.5) above at least parts of the pH curve; (b) the solubility of apatite at the pH values in plaque; (c) the area between the plaque pH solubility curve and the apatite solubility at the resting pH/critical pH; (d) the area between plaque cH+ curve and the cH+ value at resting pH/ critical pH; and (e) the area between a plaque pH curve and a cut-off pH value below the curve, e.g. pH 3. It was found that because both the cH+ and the solubility of apatite increased logarithmically with a pH drop, the two latter area functions (d, e) were basically different from those based directly on pH curves. Thus, pH changes around the resting pH value had little effect on areas calculated from concentrations of H+ and solubility. In contrast, a small pH change around pH 4 had a strong impact on both demineralization potential and areas based on cH+. Also, because of the logarithmic nature, demineralization potentials were generally large in comparison to remineralization potentials, a point that has hitherto received little attention.
authors.affiliation: Royal Dental College, University of Aarhus, Denmark.
authors.forename: M J
authors.initials: MJ
authors.lastname: Larsen
authors.forename: E I
authors.initials: EI
authors.lastname: Pearce
mesh_terms: D001031:Apatites / Q000737:chemistry*; D003747:Dental Enamel Solubility; D003773:Dental Plaque / Q000503:physiopathology*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D011381:Programming Languages; D012016:Reference Values; D012984:Software / Q000706:statistics & numerical data
chemical_list: D001031:Apatites