Various graft vs. host diseases (GvHD) in rodents can be prevented and treated by malononitrilamides (MNAs).
Schorlemmer
H U
HU
Research Laboratories Hoechst Marion Roussell (HMR), Marburg, Germany.
Kurrle
R
R
Bartlett
R R
RR
D000480:Alkynes; D000818:Animals; D006086:Graft vs Host Disease / Q000473:pathology / Q000517:prevention & control*; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007555:Isoxazoles; D008198:Lymph Nodes / Q000473:pathology; D051379:Mice; D008810:Mice, Inbred C57BL; D008811:Mice, Inbred DBA; D009570:Nitriles / Q000627:therapeutic use*; D051381:Rats; D011914:Rats, Inbred BN; D011917:Rats, Inbred Lew
D000480:Alkynes; D007166:Immunosuppressive Agents; D007555:Isoxazoles; D009570:Nitriles; C102911:X 910279; C115284:2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide