Prospective study of human herpesvirus 6, human herpesvirus 7, and cytomegalovirus infections in human immunodeficiency virus-positive patients.
Blood samples from human immunodeficiency virus (HIV)-positive patients were monitored for cytomegalovirus (CMV), human herpesvirus 6 (HHV-6), and HHV-7 by PCR. We detected CMV in 17% of the patients, HHV-6 in 6%, and HHV-7 in 3%. The viral loads of CMV were significantly higher than those of HHV-6 (P = 0.007) or HHV-7 (P = 0.01). Detection of CMV and HHV-6 was associated with low and high CD4 counts, respectively.
Fabio
G
G
Department of Virology, Royal Free Hospital School of Medicine, Hampstead, London, United Kingdom.
Knight
S N
SN
Kidd
I M
IM
Noibi
S M
SM
Johnson
M A
MA
Emery
V C
VC
Griffiths
P D
PD
Clark
D A
DA
D018791:CD4 Lymphocyte Count; D003586:Cytomegalovirus Infections / Q000097:blood / Q000150:complications*; D006679:HIV Seropositivity / Q000150:complications*; D006566:Herpesviridae Infections / Q000097:blood / Q000150:complications*; D015654:Herpesvirus 6, Human / Q000302:isolation & purification*; D016199:Herpesvirus 7, Human / Q000302:isolation & purification*; D006801:Humans; D011446:Prospective Studies