Transmission of human and feline immunodeficiency viruses via reused suture material.
Several documented cases of human immunodeficiency virus (HIV) infection have involved unconventional or unknown modes of transmission of the virus. Some such cases have occurred within a surgical setting. We investigated the potential for transmission of HIV on suture material that had been reused following passage through an HIV-infected patient. Initial experiments were conducted in vitro using HIV. To provide stronger evidence that HIV could be transmitted via this route, further experiments were undertaken in vivo using a feline immunodeficiency virus (FIV)/cat model. Both methods indicated the possibility of transmission of virus if suture materials were reused.
Druce
J D
JD
Victorian Infectious Diseases Reference Laboratory, Fairfield, Australia. julian@hna.ffh.vic.gov.au
Robinson
W F
WF
Locarnini
S A
SA
Kyaw-Tanner
M T
MT
Sommerlad
S F
SF
Birch
C J
CJ
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D001483:Base Sequence; D002415:Cats; D002460:Cell Line; D017931:DNA Primers / Q000235:genetics; D004279:DNA, Viral / Q000235:genetics / Q000302:isolation & purification; D017743:Equipment Reuse; D016181:Feline Acquired Immunodeficiency Syndrome / Q000276:immunology / Q000635:transmission* / Q000821:virology; D006678:HIV / Q000302:isolation & purification*; D015658:HIV Infections / Q000635:transmission*; D006801:Humans; D016089:Immunodeficiency Virus, Feline / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D066298:In Vitro Techniques; D016133:Polymerase Chain Reaction; D011533:Proviruses / Q000235:genetics / Q000302:isolation & purification; D013537:Sutures / Q000009:adverse effects*
D000914:Antibodies, Viral; D017931:DNA Primers; D004279:DNA, Viral