Renal duplex ultrasonography in the diagnosis and follow-up of a case of accelerated transplant rejection treated with OKT3.
Several studies have discussed the value of ultrasonography in the differential diagnosis of early renal allograft dysfunction. However, much controversy still remains regarding its real usefulness in this clinical setting. Among the causes of early graft dysfunction, accelerated rejection is one of the most serious and leads frequently to early graft loss; early diagnosis and aggressive therapy are essential to prevent irreversible graft damage or even graft rupture. Limited attention has been paid to the evaluation of accelerated rejection treated with monoclonal CD3 antibodies by means of combined B-mode and Doppler ultrasonography. We report one such a case with a favorable outcome.
Salgado
O
O
Center for Experimental Surgery, Faculty of Medicine, University of Zulia, Venezuela.
García
R
R
Henríquez
C
C
Rodríguez-Iturbe
B
B
D006084:Graft Rejection / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007668:Kidney / Q000000981:diagnostic imaging / Q000473:pathology; D016030:Kidney Transplantation / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D016853:Muromonab-CD3 / Q000627:therapeutic use*; D014463:Ultrasonography
D007166:Immunosuppressive Agents; D016853:Muromonab-CD3