[T-cell large granular lymphocytic leukemia associated with pure red cell aplasia, successfully treated with cyclophosphamide].
Authors report effective treatment of T-cell large granular lymphocyte (LGL) leukaemia and secondary pure cell aplasia with cyclophosphamide. The current classification of LGL proliferations is presented, with emphasis on the issues of diagnosis, clinical course and treatment. LGL proliferations are not so rare that previously thought and should be involved in the differential diagnosis of neutropenia, pure red cell aplasia, Felty's syndrome and vasculitis of unknown origin.
Mátrai
Z
Z
Országos Haematológiai Intézet, Haematológiai és Immunológiai Osztály, Budapest.
Lelkes
G
G
Milosevits
J
J
Páldiné
H P
HP
Pecze
K
K
D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000627:therapeutic use*; D004912:Erythrocytes / Q000648:ultrastructure; D006801:Humans; D007694:Killer Cells, Natural; D015458:Leukemia, T-Cell / Q000097:blood / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D008214:Lymphocytes / Q000648:ultrastructure; D008854:Microscopy, Electron; D012010:Red-Cell Aplasia, Pure / Q000150:complications* / Q000188:drug therapy
D018906:Antineoplastic Agents, Alkylating; D003520:Cyclophosphamide