Successful management of an infected implantable cardioverter defibrillator with oral antibiotics and without removal of the device.
Infection of an implantable cardioverter defibrillator developed 2 weeks after implantation, presenting with fever, swelling, redness, and tenderness of the skin above the generator site. A cloxacillin resistant coagulase-negative staphylococcus was repeatedly cultured from the abdominal wall pocket fluid. The infection was successfully treated with a combination of two antibiotics, fusidic acid and rifampin, given orally for 3 months. Although the device was not removed, infection did not recur during a 24-month follow-up.
Turkisher
V
V
Department of Cardiology, E. Wolfson Hospital, Holon, Israel.
Priel
I
I
Dan
M
M
D000284:Administration, Oral; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D017147:Defibrillators, Implantable / Q000009:adverse effects*; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D005672:Fusidic Acid / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012293:Rifampin / Q000627:therapeutic use*; D013203:Staphylococcal Infections / Q000188:drug therapy*; D013530:Surgical Wound Infection / Q000188:drug therapy* / Q000382:microbiology; D017180:Tachycardia, Ventricular / Q000628:therapy; D013997:Time Factors
D000900:Anti-Bacterial Agents; D005672:Fusidic Acid; D012293:Rifampin