The ability of nitric oxide (NO) inhibitors to reverse an interleukin-1 (IL-1) induced depression of proteoglycan synthesis is age dependent.
Spirito
S
S
Ciba-Geigy Corporation, Research Department, Summit, NJ 07901, USA.
Goldberg
R L
RL
D000375:Aging; D000818:Animals; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D007375:Interleukin-1 / Q000494:pharmacology*; D009569:Nitric Oxide / Q000096:biosynthesis / Q000494:pharmacology; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors*; D011509:Proteoglycans / Q000096:biosynthesis*; D011817:Rabbits
D004791:Enzyme Inhibitors; D007375:Interleukin-1; D011509:Proteoglycans; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase