Prostaglandin E2 mediates parathyroid hormone induced osteoclast formation by cyclic AMP independent mechanism.
Sato
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T
Department of Physiological Chemistry, Graduate School, Tokyo Medical and Dental University, Japan.
Morita
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Murota
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D000818:Animals; D001853:Bone Marrow / Q000187:drug effects; D001862:Bone Resorption / Q000209:etiology* / Q000503:physiopathology; D002118:Calcium / Q000378:metabolism; D002454:Cell Differentiation; D002478:Cells, Cultured; D000242:Cyclic AMP / Q000502:physiology*; D051546:Cyclooxygenase 2; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology; D003907:Dexamethasone / Q000494:pharmacology; D015232:Dinoprostone / Q000494:pharmacology* / Q000502:physiology; D004790:Enzyme Induction / Q000187:drug effects; D007213:Indomethacin / Q000494:pharmacology; D007375:Interleukin-1 / Q000494:pharmacology; D017136:Ion Transport / Q000187:drug effects; D007527:Isoenzymes / Q000096:biosynthesis / Q000235:genetics; D008297:Male; D051379:Mice; D008817:Mice, Mutant Strains; D010010:Osteoclasts / Q000187:drug effects*; D010281:Parathyroid Hormone / Q000494:pharmacology* / Q000502:physiology; D011451:Prostaglandin-Endoperoxide Synthases / Q000096:biosynthesis / Q000235:genetics; D018078:Receptors, Prostaglandin E / Q000187:drug effects; D058306:Receptors, Prostaglandin E, EP1 Subtype
D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D007375:Interleukin-1; D007527:Isoenzymes; D010281:Parathyroid Hormone; C545636:Ptger1 protein, mouse; D018078:Receptors, Prostaglandin E; D058306:Receptors, Prostaglandin E, EP1 Subtype; D003907:Dexamethasone; D000242:Cyclic AMP; D051546:Cyclooxygenase 2; D011451:Prostaglandin-Endoperoxide Synthases; D015232:Dinoprostone; D002118:Calcium; D007213:Indomethacin