title: [Propofol in continuous infusion for performing nuclear magnetic resonance in children: an effective alternative to sedation with other drugs].
abstract: Sedation is often needed for obtaining nuclear magnetic resonance (NMR) images in children. The aim of this study was to evaluate the efficacy of propofol administered by continuous infusion to non-intubated children for whom our hospital's usual method of sedation (oral chlorohydrate 75 mg/kg at a maximum dose of 2 g plus 4 hours sleep privation the night before) had failed. Deep sedation was induced in 37 ASA I-II children aged 4 and 14 year old, with 2.5 mg/kg propofol followed by 6 mg/kg/h in continuous infusion. An additional dose of 1 mg/kg was administered if the child moved, and the perfusion was reduced to 4 mg/kg if SpO2 fell below 95%. Apnea occurred after induction in 24% (n = 9), 29% (n = 11) required additional doses of propofol, and a tendency to hypercapnia was observed as the imaging procedure progressed. Sedation failed in one child, who required general anesthesia when opisthotonos presented after the induction dose. Awakening was early and satisfactory in all patients, with a score of 2 on the Ramsay scale 15 minutes after NMR. Deep sedation with propofol is a safe and effective method of performing NMR in a child for whom other methods of sedation have failed, provided the child is ASA I-II, monitoring is exhaustive and procedure is carried out by an anesthesiologist.
authors.affiliation: Servicio de Anestesiología y Reanimación, Hospital Dr. Peset, Valencia.
authors.forename: J
authors.initials: J
authors.lastname: Bellver-Romero
authors.forename: J
authors.initials: J
authors.lastname: Seller-Losada
authors.forename: V
authors.initials: V
authors.lastname: Pertusa-Collado
authors.forename: A
authors.initials: A
authors.lastname: Marqués-González
authors.forename: M
authors.initials: M
authors.lastname: Barberá Alacreu
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives / Q000008:administration & dosage; D007262:Infusions, Intravenous; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D015742:Propofol / Q000008:administration & dosage
chemical_list: D006993:Hypnotics and Sedatives; D015742:Propofol