title: Tamoxifen induced endometrial abnormalities: evaluation by saline infusion sonohysterography.
abstract: Patients receiving tamoxifen therapy for breast cancer are at an increased risk for endometrial hyperplasia, polyps, and adenocarcinoma. Therefore, any bleeding in the post-menopausal patient on tamoxifen warrants further investigation. Sonohysterography is a new technique for evaluating the uterine cavity and clarifying the location of endometrial and peri-endometrial processes. Differentiating subendometrial cyst formation from endometrial proliferation can save patients from further, invasive investigative diagnostic procedures.
authors.affiliation: Department of Diagnostic Radiology, University of Maryland Medical Center, USA.
authors.forename: B M
authors.initials: BM
authors.lastname: Jaeger
authors.forename: K
authors.initials: K
authors.lastname: Grumbach
mesh_terms: D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects*; D003560:Cysts / Q000139:chemically induced / Q000000981:diagnostic imaging; D004717:Endometrium / Q000000981:diagnostic imaging* / Q000187:drug effects* / Q000473:pathology; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008875:Middle Aged; D017698:Postmenopause; D012965:Sodium Chloride; D013629:Tamoxifen / Q000009:adverse effects*; D014463:Ultrasonography / Q000379:methods; D014591:Uterine Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging; D014592:Uterine Hemorrhage / Q000139:chemically induced / Q000000981:diagnostic imaging*
chemical_list: D018931:Antineoplastic Agents, Hormonal; D013629:Tamoxifen; D012965:Sodium Chloride