title: Critical role of arachidonate lipoxygenases in regulating apoptosis.
authors.affiliation: Department of Radiation Oncology, Wayne State University, Detroit, Michigan 48202, USA.
authors.forename: D G
authors.initials: DG
authors.lastname: Tang
authors.forename: A T
authors.initials: AT
authors.lastname: Porter
authors.forename: K V
authors.initials: KV
authors.lastname: Honn
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000187:drug effects / Q000502:physiology*; D001092:Arachidonate 12-Lipoxygenase / Q000235:genetics / Q000502:physiology; D016718:Arachidonic Acid / Q000502:physiology*; D001710:Biotin / Q000031:analogs & derivatives / Q000494:pharmacology; D015777:Eicosanoids / Q000502:physiology; D008084:Lipoxygenase / Q000502:physiology*; D016859:Lipoxygenase Inhibitors / Q000494:pharmacology; D008322:Mammals / Q000378:metabolism; D008563:Membrane Lipids / Q000502:physiology*; D008954:Models, Biological; D009000:Monocytes / Q000187:drug effects / Q000378:metabolism; D016376:Oligonucleotides, Antisense / Q000494:pharmacology; D010590:Phalloidine / Q000031:analogs & derivatives / Q000494:pharmacology; D010741:Phospholipases A / Q000502:physiology; D011451:Prostaglandin-Endoperoxide Synthases / Q000502:physiology; D051381:Rats
chemical_list: D015777:Eicosanoids; D016859:Lipoxygenase Inhibitors; D008563:Membrane Lipids; D016376:Oligonucleotides, Antisense; C060047:4-(3-(biotinylaminohexamethylenaminocarbonyl)propanoylaminomethyl)-2-methyl-1,3-dithiolane-2-yl-(Ala(7))phalloidin; D010590:Phalloidine; D016718:Arachidonic Acid; D001710:Biotin; D008084:Lipoxygenase; D001092:Arachidonate 12-Lipoxygenase; D011451:Prostaglandin-Endoperoxide Synthases; D010741:Phospholipases A