Renal vasculitis with HIV seropositivity: potential manifestation of cytomegalovirus infection.
The associations among human immunodeficiency virus (HIV) infection, focal segmental glomerulosclerosis, and its variant, "collapsing glomerulopathy," often leading to chronic renal failure, are well described. HIV-seropositive patients may also develop a variety of immune complex-mediated glomerular diseases, including postinfectious glomerulonephritis, IgA nephropathy, and membranoproliferative glomerulonephritis. Herein we describe a case of pauci-immune necrotizing renal vasculitis in an HIV-seropositive patient, thereby expanding the differential diagnosis of acute renal failure in this setting.
Chertow
G M
GM
Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Rennke
H G
HG
Curhan
G C
GC
Brady
H R
HR
D003586:Cytomegalovirus Infections / Q000150:complications* / Q000175:diagnosis; D003937:Diagnosis, Differential; D005923:Glomerulosclerosis, Focal Segmental / Q000209:etiology*; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D007668:Kidney / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D014657:Vasculitis / Q000209:etiology*