[The hepatoprotective and hyoplipidemic effect of flower pollen lipid extract in androgenized rats].
Hepatoprotective, hypolipidemic and hypocholesterolemic effects of the lipid flower pollen extract in subchronically testosterone-androgenized rats were shown. Normalization of AspAT, A1AT and alkaline phosphatase--biochemical indicators of necrotic changes in the hepatic cell--substantially testifies to the hepatoprotective effect of the investigated lipid flower pollen extract on the hepatic cell, and constitutes a premise for further clinical studies.
Polański
M
M
Katedra Farmakodynamiki Collegium Medicum UJ.
Czarnecki
R
R
Woroń
J
J
D000410:Alanine Transaminase / Q000187:drug effects / Q000378:metabolism; D000469:Alkaline Phosphatase / Q000187:drug effects / Q000378:metabolism; D000818:Animals; D001219:Aspartate Aminotransferases / Q000187:drug effects / Q000378:metabolism; D015415:Biomarkers / Q000032:analysis; D002784:Cholesterol / Q000097:blood; D008055:Lipids / Q000097:blood*; D008099:Liver / Q000187:drug effects* / Q000201:enzymology / Q000473:pathology; D008297:Male; D009336:Necrosis; D010936:Plant Extracts / Q000494:pharmacology*; D011058:Pollen; D051381:Rats; D017208:Rats, Wistar; D013739:Testosterone / Q000633:toxicity
D015415:Biomarkers; D008055:Lipids; D010936:Plant Extracts; D013739:Testosterone; D002784:Cholesterol; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase