title: A 10-year longitudinal study of tubal function in patients with nasopharyngeal carcinoma after irradiation.
abstract: OBJECTIVE
  To follow up the chronological change of tubal function in patients with nasopharyngeal carcinoma for 10 years after irradiation.
  
  
  METHODS
  Patients with nasopharyngeal carcinoma were subjected to eustachian tube function tests before irradiation and 6 months, 5 years, and 10 years after irradiation.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  Ten patients (20 ears), 7 men and 3 women.
  
  
  RESULTS
  Twelve (60%) of the ears had patulous tubes 10 years after irradiation, which might result from atrophy of peritubal tissues. The occurrence of a patulous tube was independent of the radiation dosage, but it was related to the interval since irradiation.
  
  
  CONCLUSIONS
  Development of a patulous tube is associated with correction of organic obstruction of the eustachian tube. Resolution of the inflammatory reaction plays the most important role in recovery of function of the tube. Therefore, the prevalence of middle ear complications is low 10 years after irradiation.
authors.affiliation: Department of Otolaryngology, National Taiwan University, Taipei.
authors.forename: Y H
authors.initials: YH
authors.lastname: Young
authors.forename: P W
authors.initials: PW
authors.lastname: Cheng
authors.forename: J Y
authors.initials: JY
authors.lastname: Ko
mesh_terms: D000328:Adult; D000368:Aged; D001284:Atrophy; D002277:Carcinoma / Q000150:complications / Q000532:radiotherapy*; D004396:Coloring Agents; D005064:Eustachian Tube / Q000473:pathology / Q000502:physiology / Q000528:radiation effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007203:Indigo Carmine; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000150:complications / Q000532:radiotherapy*; D010033:Otitis Media / Q000209:etiology / Q000628:therapy; D010034:Otitis Media with Effusion / Q000209:etiology / Q000628:therapy; D011312:Pressure; D015995:Prevalence; D011879:Radiotherapy Dosage; D013997:Time Factors
chemical_list: D004396:Coloring Agents; D007203:Indigo Carmine