Effect of n-3 polyunsaturated fatty acids on the lipidic profile of healthy Mexican volunteers.
OBJECTIVE
The effect of n-3 polyunsaturated fatty acids on the serum lipid profile in a Mexican population was evaluated.


METHODS
Three g of salmon oil was the daily intake during four weeks. Total cholesterol, triglycerides, low density lipoproteins, high density lipoproteins and erythrocyte fatty acid composition were analyzed.


RESULTS
The hypertriglyceridemic group showed a statistically significant (p < 0.05) reduction of triglycerides and significant (p < 0.01) elevation of high density lipoproteins. The hypercholesterolemic group reduced significantly the levels of cholesterol and triglycerides; high density lipoproteins were augmented by 11.6%.


CONCLUSIONS
The hypolipidemic effect of n-3 polyunsaturated fatty acids was manifest in the Mexican volunteers under the conditions here evaluated.
Carvajal
O
O
Instituto Tecnológico de Veracruz, Departamento de Ingenlería Química y Bioquímica, Veracruz, México.
Angulo
O
O
D000328:Adult; D000818:Animals; D002784:Cholesterol / Q000097:blood; D002849:Chromatography, Gas; D003627:Data Interpretation, Statistical; D004281:Docosahexaenoic Acids / Q000494:pharmacology; D015118:Eicosapentaenoic Acid / Q000494:pharmacology; D004910:Erythrocyte Membrane / Q000737:chemistry; D015525:Fatty Acids, Omega-3 / Q000494:pharmacology*; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood; D006949:Hyperlipidemias / Q000097:blood; D015228:Hypertriglyceridemia / Q000097:blood; D008055:Lipids / Q000097:blood*; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D012474:Salmon; D014280:Triglycerides / Q000097:blood
D015525:Fatty Acids, Omega-3; D008055:Lipids; D008077:Lipoproteins, LDL; D014280:Triglycerides; D004281:Docosahexaenoic Acids; D002784:Cholesterol; D015118:Eicosapentaenoic Acid