[Surgical treatment of advanced lung emphysema. Does it really improve treatment results?].
Lung emphysema may be one of the components of chronic obstructive pulmonary disease (COPD). Nearly 60% of patients with advanced chronic respiratory insufficiency with FEV1 < 30% expected, aged > 65 years die within the first 2 years of the disease. The treatment of COPD includes oxygen therapy, lung transplantation and/or lung volume reduction (LVR). The study presents qualification criteria for LVR in reference to oxygen therapy and lung transplantation. Crucial diagnostic features include: CT of the chest with densitometric analysis and lung perfusion scans. Patients with severe but limited dyspnea, disseminated emphysema lesions with fairly untouched areas of normal lung tissue, FEV1% < 30-35%, DLCO < 25% expected, PaCO2 < or = 50 mmHg and PaO2 < or = 50-55 mmHg, appear to be the best candidates for LVR. The results of the study indicate, that in Poland, patients with advanced emphysema, who are treated with oxygen therapy or soon will be qualified this therapy or await lung transplantation might be candidates for LVR. The early results of lung volume reduction are promising and include: decrease in total lung capacity, residual volume and breathing frequency. LVR has been in use for about 3 years and majority of authors still do not possess clinical observations long enough to obtain statistically significant comparison with other methods of treatment. Limited morbidity and low perioperative mortality enable application of LVR even in patients with severe respiratory insufficiency and/or requiring constant oxygen therapy. In conclusion considering all positive aspects of LVR it is necessary to emphasise that for overall assessment of this method a broader clinical material is required including data on duration of clinical improvement.
Furmanik
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F
Jabłonka
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D000368:Aged; D003937:Diagnosis, Differential; D004646:Emphysema / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000601:surgery; D008173:Lung Diseases, Obstructive / Q000150:complications / Q000175:diagnosis; D016040:Lung Transplantation; D010100:Oxygen / Q000627:therapeutic use; D011859:Radiography; D011877:Radionuclide Imaging; D012129:Respiratory Function Tests
D010100:Oxygen