title: [Small-cell sarcoma of the esophagus as a fourth malignancy. Its palliative therapy with argon gas coagulation].
abstract: METHODS
  A prostatic carcinoma, an early gastric carcinoma and a colon carcinoma had occurred over 15 years in a now 82-year-old patient. He was now admitted because of severe dysphagia.
  
  
  METHODS
  Gastroscopy revealed an exophytic tumour of the oesophagus, histologically identified as a small-cell sarcoma. It had caused a 12 cm long severe eccentric stenosis of the oesophagus. Tissue from the previous three tumours were examined immunohistochemically for p-53 gene mutation, but only the oesophageal sarcoma gave positive results.
  
  
  METHODS
  After part of exophytic tumour had been ablated by argon gas coagulation a prosthetic tube was implanted. Bleeding from erosion of a large metastasis in the gastric fundus was successfully treated by argon gas coagulation 4 months after the previous discharge, but the patient died of the malignancy 1/1 and half months later.
  
  
  CONCLUSIONS
  The consecutive occurrence of four different malignant tumours is rare even in advanced age. In this case the malignancies were presumably unrelated and it demonstrates the possibility of removing an eccentric tumour stenosis by argon gas coagulation before implanting a prosthesis.
authors.affiliation: Abteilung für Allgemeine Innere Medizin und Gastroenterologie, Herz-Jesu-Krankenhaus, Fulda.
authors.forename: J
authors.initials: J
authors.lastname: Glaser
authors.forename: H
authors.initials: H
authors.lastname: Arps
authors.forename: M
authors.initials: M
authors.lastname: Rübsam
authors.forename: T
authors.initials: T
authors.lastname: Hack
mesh_terms: D000368:Aged; D002277:Carcinoma / Q000601:surgery*; D002299:Cardia; D003110:Colonic Neoplasms / Q000601:surgery*; D004938:Esophageal Neoplasms / Q000175:diagnosis / Q000601:surgery*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D018365:Neoplasm, Residual; D016609:Neoplasms, Second Primary / Q000175:diagnosis / Q000601:surgery*; D010166:Palliative Care / Q000379:methods*; D011471:Prostatic Neoplasms / Q000601:surgery*; D011708:Pylorus; D018228:Sarcoma, Small Cell / Q000175:diagnosis / Q000601:surgery*; D013274:Stomach Neoplasms / Q000556:secondary / Q000601:surgery*