An unusual case of urinary incontinence, ataxia-telangiectasia, and metastatic dysgerminoma: case report and review of the literature.
Ataxia-telangiectasia (A-T) is a rare autosomal recessive disease notable for neurodegeneration, chromosomal instability, and a predisposition to cancer. It presents in childhood with a variable phenotype. We report the first case of an A-T related tumor presenting as urinary incontinence, and the first case of 2-year survival in an A-T patient with metastatic dysgerminoma.
deVries
C R
CR
Section of Urology, Medical College of Georgia, Augusta 30912-4050, USA.
Kaplan
G W
GW
D000293:Adolescent; D001260:Ataxia Telangiectasia / Q000150:complications*; D004407:Dysgerminoma / Q000150:complications* / Q000556:secondary; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000150:complications* / Q000473:pathology; D014549:Urinary Incontinence / Q000209:etiology*