title: Case report. An unusual case of precocious puberty.
abstract: An almost 3-year-old boy was evaluated for pubic hair and unilateral testicular enlargement 1 week after resection of an astrocytoma of the posterior fossa. Rather than the expected diagnosis of central precocity due to increased intracranial pressure, a diagnosis of congenital adrenal hyperplasia (21-hydroxylase deficiency) with testicular adrenal rest cells was made. The differential diagnosis, laboratory evaluation, and currently accepted medical management of congenital adrenal hyperplasia are described.
authors.affiliation: Yale University School of Medicine, New Haven, CT 06520, USA.
authors.forename: S D
authors.initials: SD
authors.lastname: Boulware
mesh_terms: D000312:Adrenal Hyperplasia, Congenital / Q000150:complications* / Q000175:diagnosis* / Q000628:therapy; D001254:Astrocytoma / Q000150:complications / Q000601:surgery; D001932:Brain Neoplasms / Q000150:complications / Q000601:surgery; D002675:Child, Preschool; D003388:Cranial Fossa, Posterior; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D011629:Puberty, Precocious / Q000209:etiology*