Stability of C3 convertase in the rat classical complement pathway.
It has been reported that rat serum complement causes efficient hemolysis of antibody-sensitized sheep erythrocytes (EA) at 20 C but not at 37 C. In connection with this, we demonstrated that C3 convertase of rat complement was significantly unstable at 37 C using purified components of rat complement.
Naito
A
A
Department of Molecular Biology, Nagoya City University School of Medicine, Aichi, Japan.
Okada
H
H
D000818:Animals; D003175:Complement C2 / Q000302:isolation & purification* / Q000378:metabolism; D050577:Complement C3-C5 Convertases / Q000378:metabolism*; D006168:Guinea Pigs; D006461:Hemolysis; D051381:Rats; D013696:Temperature
D003175:Complement C2; D050577:Complement C3-C5 Convertases