title: [The characteristics of the clinical course of nephritis in patients with cryoglobulinemia].
abstract: Cryoglobulins were measured spectrophotometrically in the sera of 40 patients with renal diseases. 18 of them had chronic glomerulonephritis, 14 lupus nephritis and 8 nephritis. 20 patients with high concentration of cryoglobulins (100-600 micrograms/ml) exhibited high incidence of nephrotic syndrome (80%), arterial hypertension (90%), creatininemia (70%) and, respectively, 25, 25 and 15% of patients free of cryoglobulinemia. There was a correlation between cryoglobulins level and creatininemia (r = 0.468), proteinuria (r = 0.478), ESR (r = 0.393), systolic and diastolic arterial pressure (r = 0.393 and r = 342, respectively). An inverse relation existed with serum albumins (r = -0.526). Progression of renal failure was associated with high cryoglobulinemia. In decline of cryoglobulins content there was clinical improvement, lowering or normalization of blood creatinin levels.
authors.forename: N B
authors.initials: NB
authors.lastname: Gordovskaia
authors.forename: V V
authors.initials: VV
authors.lastname: Azarova
authors.forename: V B
authors.initials: VB
authors.lastname: Artem'eva
authors.forename: I Iu
authors.initials: IIu
authors.lastname: Kulikova
authors.forename: N A
authors.initials: NA
authors.lastname: Konstantinova
authors.forename: L V
authors.initials: LV
authors.lastname: Kozlovskaia
mesh_terms: D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D003404:Creatinine / Q000097:blood; D003449:Cryoglobulinemia / Q000097:blood*; D003450:Cryoglobulins / Q000032:analysis; D005260:Female; D005921:Glomerulonephritis / Q000097:blood; D006801:Humans; D008181:Lupus Nephritis / Q000097:blood; D008297:Male; D008875:Middle Aged; D009393:Nephritis / Q000097:blood*; D014657:Vasculitis / Q000097:blood
chemical_list: D003450:Cryoglobulins; D003404:Creatinine