title: Early computed tomography is rarely necessary in gallstone pancreatitis.
abstract: The role of early CT scanning in acute gallstone pancreatitis remains ill defined. The purpose of our study was to: 1) determine whether our previously identified admission prognostic factors for gallstone pancreatitis [white blood cell (WBC) count > or = 14.5 x 10(9)/L, blood urea nitrogen (BUN) > or = 12 mmol/L, Acute and Chronic Health Evaluation II score > or = 5, glucose > or = 150 mg/dL, and heart rate > or = 100 beats/min)] correlate with the severity of pancreatic inflammation on CT scan, and 2) to determine the utility of early CT scanning in the management of gallstone pancreatitis. Admission clinical and laboratory variables were collected prospectively. Early CT scan findings were graded using the Balthazar scoring system and subgrouped into mild-moderate (Balthazar grades A-C) or severe (grades D and E) by a radiologist blinded to the patients' clinical status. Ninety-seven patients underwent surgery during their initial hospitalization without preoperative CT scanning. Four had operative complications (4%). Forty-two patients underwent early CT scan (grade A, 19%; B, 5%; C, 21%; D, 10%; and E, 45%), but only four (all grade E) had surgery delayed because of necrotizing pancreatitis, abscess, or pseudocyst. All four had persistent abdominal pain. There was one (2.5%) operative complication in the CT group and no deaths. Admission WBC count > or = 14.5 x 10(9)/L and BUN > or = 12 mmol/L correlated with severe pancreatitis (grades D and E) on CT (P < .05). We conclude that in patients with gallstone pancreatitis, 1) admission WBC count > or = 14.5 x 10(9)/L and BUN > or = 12 mmol/L correlate with the severity of pancreatic inflammation on CT scan, and 2) CT scan findings rarely influence management decisions and CT is therefore unnecessary, except in the minority of patients with objective indications of severe or unresolving pancreatitis.
authors.affiliation: Department of Surgery, Harbor-UCLA Medical Center, Torrance 90509, USA.
authors.forename: K
authors.initials: K
authors.lastname: Toosie
authors.forename: L
authors.initials: L
authors.lastname: Chang
authors.forename: R
authors.initials: R
authors.lastname: Renslo
authors.forename: T
authors.initials: T
authors.lastname: Arnell
authors.forename: F
authors.initials: F
authors.lastname: Bongard
authors.forename: B E
authors.initials: BE
authors.lastname: Stabile
authors.forename: C
authors.initials: C
authors.lastname: de Virgilio
mesh_terms: D018806:APACHE; D015746:Abdominal Pain / Q000000981:diagnostic imaging; D000038:Abscess / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery; D000328:Adult; D001786:Blood Glucose / Q000032:analysis; D001806:Blood Urea Nitrogen; D002769:Cholelithiasis / Q000150:complications / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000601:surgery; D003657:Decision Making; D005260:Female; D006339:Heart Rate; D006760:Hospitalization; D006801:Humans; D007431:Intraoperative Complications; D007958:Leukocyte Count; D008297:Male; D010182:Pancreatic Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery; D010192:Pancreatic Pseudocyst / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery; D010195:Pancreatitis / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery; D019283:Pancreatitis, Acute Necrotizing / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery; D010343:Patient Admission; D010347:Patient Care Planning; D011379:Prognosis; D011446:Prospective Studies; D011871:Radiology; D012680:Sensitivity and Specificity; D016037:Single-Blind Method; D014057:Tomography, X-Ray Computed
chemical_list: D001786:Blood Glucose