title: [Effects of simulated weightlessness on the hypophyseal-cortical-adrenal axis in the pregnant rat].
abstract: The eventual part of stress in the hormonal responses to simulated weightlessness was studied during gestation in the rat. We have compared these responses with the effects of two other situations well-known to provoke stress: ultrasounds and denutrition. An increase of blood and adrenal corticosterone levels was found in mothers after denutrition, neither after ultrasounds nor after simulated weightlessness. In foetuses, a decrease of weight was noted after denutrition and simulated weightlessness. Foetal suprarenal corticosterone remained normal when mothers were submitted to simulated weightlessness. In this group, a decrease in foetal weight was found that could be explained by non suprarenal hormonal factors or by circulation disturbances.
authors.affiliation: Département de Biologie, Faculté des Sciences de Tunis, Tunisie.
authors.forename: S
authors.initials: S
authors.lastname: el Fazaa
authors.forename: N
authors.initials: N
authors.lastname: Gharbi
authors.forename: G
authors.initials: G
authors.lastname: Gauquelin
authors.forename: C
authors.initials: C
authors.lastname: Gharib
authors.forename: A
authors.initials: A
authors.lastname: Kamoun
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001835:Body Weight; D003345:Corticosterone / Q000378:metabolism; D005260:Female; D005333:Fetus / Q000502:physiology; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology*; D010913:Pituitary-Adrenal System / Q000502:physiology*; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar; D018474:Weightlessness Simulation
chemical_list: D003345:Corticosterone