Analysis of axon tract formation in the zebrafish brain: the role of territories of gene expression and their boundaries.
Mutant analysis in the zebrafish is revealing the genes that are expressed in the early neuroepithelium and that regulate factors responsible for the guidance of commissural axons. We review work on the developing zebrafish brain illustrating the way in which territories of regulatory gene expression influence the formation and positioning of axon pathways.
Wilson
S W
SW
Developmental Biology Research Centre, Randall Institute, King's College, 26-29 Drury Lane, London, WC2B 5RL, UK.
Brennan
C
C
Macdonald
R
R
Brand
M
M
Holder
N
N
D000818:Animals; D001370:Axonal Transport; D001921:Brain / Q000166:cytology* / Q000502:physiology*; D002450:Cell Communication; D005786:Gene Expression Regulation; D009474:Neurons / Q000166:cytology* / Q000502:physiology*; D014157:Transcription Factors / Q000502:physiology*; D015027:Zebrafish
D014157:Transcription Factors