[Procedure for complex toxico-genetical investigations].
A biomonitoring system is proposed, which involves measurement of environmental genetoxicants, determination of mutagenic accumulation in biological substrates of human beings and the severity of genetic abnormalities in their somatic cells. The toxicogenetical monitoring system includes the assessment of the examinees mental status. The results of application of the system are given by using as an example two Yaroslavl (machine-building and oil-processing) plants.
Revazova
I A
IA
HII of Profilactic Toxicology and Disinfection, Moscow.
Ingel'
F I
FI
Tsutsman
T E
TE
Khripach
L V
LV
Krivtsova
E K
EK
Iurchenko
V V
VV
Gevorkian
N M
NM
D000328:Adult; D000818:Animals; D002273:Carcinogens / Q000009:adverse effects* / Q000032:analysis; D004273:DNA, Neoplasm / Q000187:drug effects / Q000235:genetics; D004784:Environmental Monitoring / Q000379:methods*; D006801:Humans; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D008875:Middle Aged; D016296:Mutagenesis / Q000187:drug effects*; D009153:Mutagens / Q000009:adverse effects* / Q000032:analysis; D009374:Neoplasms, Experimental / Q000139:chemically induced* / Q000235:genetics / Q000378:metabolism; D016273:Occupational Exposure / Q000009:adverse effects*; D012189:Retrospective Studies
D002273:Carcinogens; D004273:DNA, Neoplasm; D009153:Mutagens