title: [Genetic diagnosis and therapy of hereditary breast carcinoma].
abstract: Congenital genetic disturbances in the genes BRCA1 and BRCA2 could lead to the forming of mamacarcinoma and ovarian carcinomas. The probability of illness is by an existing gene defect very high, and mostly young women are already affected. A direct anamnestic identification of high risk person with a following proof of gene mutations could help the patient. The way of the clinical-consultation which is recommending the BRCA1-BRCA2-test in reasons for an early recognition diagnosis is at the moment subject in clinical and scientific research.
authors.affiliation: Zentrum fur Gynakologie im Krankenhaus Maingau vom Roten Kreuz Frankfurt am Main.
authors.forename: Z
authors.initials: Z
authors.lastname: Hrgović
authors.forename: M
authors.initials: M
authors.lastname: Kaufmann
authors.forename: J
authors.initials: J
authors.lastname: Loncar
authors.forename: A
authors.initials: A
authors.lastname: Salihagić
authors.forename: U
authors.initials: U
authors.lastname: Langenbeck
mesh_terms: D024682:BRCA2 Protein; D001943:Breast Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D005260:Female; D019398:Genes, BRCA1; D016147:Genes, Tumor Suppressor; D005819:Genetic Markers; D006801:Humans; D009363:Neoplasm Proteins / Q000235:genetics; D012307:Risk Factors; D014157:Transcription Factors / Q000235:genetics
chemical_list: D024682:BRCA2 Protein; D005819:Genetic Markers; D009363:Neoplasm Proteins; D014157:Transcription Factors