[Abnormal agglutination by reducing surface charge of red cell membrane as source of error in ABO typing and actual cases of incompatible ABO blood transfusion due to various factors].
T activation of red cells results from the effects of microbial sialidase catalysing the cleavage of sialic acid from red cell membrane. Abnormal agglutination may be induced when human-derived antiA,B antibodies containing antiT are used. By the using of mouse-derived antiA,B monoclonal antibodies this type of polyagglutination as source of error could be overcome. Most common cause of ABO mismatch is due to more simple technical or clerical error resulting in transfusion of the wrong blood to the recipient. Three such cases with non-fatal hemolytic transfusion reaction are described.
Okada
K
K
Department of Basic Nursing and Health Sciences, Hiroshima University, School of Medicine.
D000293:Adolescent; D000368:Aged; D001777:Blood Coagulation; D001787:Blood Group Incompatibility / Q000209:etiology*; D001788:Blood Grouping and Crossmatching; D004910:Erythrocyte Membrane / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008564:Membrane Potentials / Q000502:physiology