Magnetic source imaging combined with image-guided frameless stereotaxy: a new method in surgery around the motor strip.
OBJECTIVE
In this study, information about the localization of the central sulcus obtained by magnetic source imaging (MSI) was intraoperatively translated to the brain, using frameless image-guided stereotaxy. In the past, the MSI results could be translated to the surgical space only by indirect methods (e.g., the comparison of the MSI results, displayed in surface renderings, with bony landmarks or blood vessels on the exposed brain surface).


METHODS
Somatosensory evoked fields were recorded with a MAGNES II biomagnetometer (Biomagnetic Technologies Inc., San Diego, CA). Using the single equivalent current dipole model, the localization of the somatosensory cortex was superimposed on magnetic resonance imaging with a self-developed contour fit program. The magnetic resonance image set containing the magnetoencephalographic dipole was then transferred to a frameless image-guided stereotactic system. Intraoperatively, the gyrus containing the dipole was identified as the postcentral gyrus, using neuronavigation, and the next anterior sulcus was regarded as the central sulcus. With intraoperative cortical recording of somatosensory evoked potentials, this assumption was verified in each case.


RESULTS
In all cases, the preoperatively assumed localization of the central sulcus and motor cortex with MSI agreed with the intraoperative identification of the central sulcus using the phase reversal technique.


CONCLUSIONS
The combined use of MSI and a frameless stereotactic system allows a fast orientation of eloquent brain areas during surgery. This may contribute to a safer and more radical surgery in lesions adjacent to the motor cortex.
Ganslandt
O
O
Department of Neurosurgery, University of Erlangen-Nürnberg, Germany.
Steinmeier
R
R
Kober
H
H
Vieth
J
J
Kassubek
J
J
Romstöck
J
J
Strauss
C
C
Fahlbusch
R
R
D000368:Aged; D001931:Brain Mapping / Q000295:instrumentation; D001932:Brain Neoplasms / Q000175:diagnosis / Q000601:surgery; D003196:Computer Graphics / Q000295:instrumentation; D004867:Equipment Design; D005073:Evoked Potentials, Somatosensory / Q000502:physiology; D005260:Female; D005625:Frontal Lobe / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D015225:Magnetoencephalography / Q000295:instrumentation; D016343:Monitoring, Intraoperative / Q000295:instrumentation; D009044:Motor Cortex / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D010296:Parietal Lobe / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D013003:Somatosensory Cortex / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D013238:Stereotaxic Techniques / Q000295:instrumentation*