Clozapine for the control of hemiballismus.
Pharmacological agents used for the control of ballistic movements include chloral hydrate, barbiturates, paraldehyde, bromides, phenothiazines, progabide, haloperidol, pimozide, reserpine, tetrabenazine, sodium valproate, and dimethylaminoethanol. These agents are believed to act by different mechanisms, including modification of dopaminergic, GABAergic, or cholinergic mechanisms. We report a case where, after failure of haloperidol, phenobarbital, and pimozide, the hemiballistic movements were controlled with clozapine.
Bashir
K
K
Department of Neurology, Southern Illinois University School of Medicine, Springfield 62794-9230, USA.
Manyam
B V
BV
D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D003024:Clozapine / Q000627:therapeutic use*; D006220:Haloperidol / Q000627:therapeutic use; D006801:Humans; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D008297:Male; D009069:Movement Disorders / Q000188:drug therapy*; D010634:Phenobarbital / Q000627:therapeutic use; D010868:Pimozide / Q000627:therapeutic use
D000927:Anticonvulsants; D014150:Antipsychotic Agents; D006993:Hypnotics and Sedatives; D010868:Pimozide; D003024:Clozapine; D006220:Haloperidol; D010634:Phenobarbital