Manuifolins D, E, and F: new isoflavonoids from Maackia tenuifolia.
Chemical examination of roots of Maackia tenuifolia yielded three new isoflavans, manuifolins D, E, and F, along with the known (6aR, 12aR)-pterocarpin and (6aR,12aR)-maackiain. The new compounds were established as (3R)-5'-(1,1-dimethyl-2-propenyl)-4'- O-(3-methyl-2-butenyl)- 7,2'-dihydroxyisoflavan (1), (3R)-6,5'-bis(1,1-dimethyl-2-propenyl)-7,2',4', -trihydroxyisoflavan (2), and (3R)-5'-(1-isopropylethenyl)-8-(3-methyl-2-butenyl)-7,2',4'- trihydroxyisoflavan (3), respectively, by spectroscopic methods.
Zeng
J F
JF
State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, China.
Li
G L
GL
Shen
J K
JK
Zhu
D Y
DY
Chen
K
K
Lee
K H
KH
D007887:Fabaceae / Q000737:chemistry*; D005419:Flavonoids / Q000302:isolation & purification* / Q000494:pharmacology; D007529:Isoflavones; D009682:Magnetic Resonance Spectroscopy; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal
D005419:Flavonoids; D007529:Isoflavones; C108751:manuifolin D; C108752:manuifolin E; C108753:manuifolin F