Adult T-cell leukemia/lymphoma presenting with digital gangrene.
There have been only a few reports in the literature of lymphoma patients suffering from digital gangrene. The present case, a 40-year old man with adult T-cell leukemia/lymphoma (ATLL) showed marked edematous and dyshidrosis-like changes of the digital fingers. As a result of these changes, most of the fingertips of this patient were affected by gangrene. Histologically, lesions showed organized thrombi occluding veins in the middle dermis. In patients suffering from malignant lymphoma, digital swelling and pain associated with cyanosis should receive careful attention because of the possibility of digital gangrene. To our knowledge, this report is on the first ATLL case in the literature presenting with digital gangrene associated with occlusive thrombi.
Setoyama
M
M
Department of Dermatology, Faculty of Medicine, Kagoshima University, Japan.
Yamamoto
S
S
Kanzaki
T
T
D000328:Adult; D001157:Arterial Occlusive Diseases / Q000150:complications / Q000473:pathology; D001707:Biopsy, Needle; D015139:Blotting, Southern; D003937:Diagnosis, Differential; D005385:Fingers; D005734:Gangrene / Q000209:etiology* / Q000473:pathology; D006801:Humans; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000150:complications / Q000175:diagnosis*; D008297:Male