title: Radiation doses deriving from patients undergoing 111In-DTPA-D-phe-1-octreotide scintigraphy.
abstract: The purpose of this study was to estimate the radiation doses to nursing staff, other patients, accompanying persons and family members deriving from patients undergoing 111In-DTPA-d-Phe-1-octreotide (111In-OCT) scintigraphy. Dose rates were measured from 16 patients who had received an intravenous injection of 140+/-40 MBq 111In-OCT. The measurements were performed at three different distances (0.5, 1 and 2 m) at 10-20 min, 5-7 h and 24 h (and in some cases, up to 48 h) after administration of 111In-OCT. The effective half-lives of the biexponential decrease of the dose rates were estimated to be 2.94+/-0.27 h (T1) and 65.17+/-0. 58 h (T2). The calculated maximum dose to other persons in the waiting area was 27.2 microSv, to family members 61.5 microSv, to nursing staff in a ward 24.1 microSv and to neighbouring patients in the ward 69.5 microSv. Our results clearly demonstrate that the calculated maximum radiation exposure to accompanying persons, personnel, family members and other patients is well below the maximum annual dose limit for non-professionally exposed persons.
authors.affiliation: Department of Nuclear Medicine, University of Vienna, Austria.
authors.forename: A
authors.initials: A
authors.lastname: Kurtaran
authors.forename: J
authors.initials: J
authors.lastname: Pfreitfellner
authors.forename: P
authors.initials: P
authors.lastname: Schaffarich
authors.forename: P
authors.initials: P
authors.lastname: Smith-Jones
authors.forename: B
authors.initials: B
authors.lastname: Niederle
authors.forename: M
authors.initials: M
authors.lastname: Raderer
authors.forename: I
authors.initials: I
authors.lastname: Virgolini
authors.forename: H
authors.initials: H
authors.lastname: Bergmann
authors.forename: E
authors.initials: E
authors.lastname: Havlik
mesh_terms: D000396:Air Pollutants, Radioactive; D000553:Ambulatory Care; D004781:Environmental Exposure; D005190:Family; D006801:Humans; D007205:Indium Radioisotopes; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging; D009740:Nursing Staff; D015282:Octreotide / Q000031:analogs & derivatives*; D004369:Pentetic Acid / Q000031:analogs & derivatives*; D011829:Radiation Dosage; D011835:Radiation Protection; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013997:Time Factors
chemical_list: D000396:Air Pollutants, Radioactive; D007205:Indium Radioisotopes; D019275:Radiopharmaceuticals; C071632:SDZ 215-811; D004369:Pentetic Acid; D015282:Octreotide