Clearance of cervical human papillomavirus infection by treatment for cervical dysplasia.
OBJECTIVE
The aim of this study was to investigate the prevalence of human papillomavirus (HPV) after treatment for cervical dysplasia.


METHODS
The presence of HPV was investigated in cervical scrapes of 91 patients, before and after treatment, using consensus primers in the polymerase chain reaction.


RESULTS
Before treatment for cervical dysplasia, 89 of 91 patients (98%) were HPV-positive compared with 28 of 91 patients (31%) after treatment. The HPV type present before treatment was found in the scrapes of only 9 of 89 patients (10%). Detection of HPV after treatment was associated with human immunodeficiency virus infection and incomplete conization.


CONCLUSIONS
The HPV type present before treatment was frequently cleared by treatment for cervical dysplasia.
Bollen
L J
LJ
Department of Virology, University of Amsterdam, Academic Medical Center, The Netherlands.
Tjong-A-Hung
S P
SP
van der Velden
J
J
Mol
B W
BW
Boer
K
K
ten Kate
F J
FJ
Bleker
O P
OP
ter Schegget
J
J
D000328:Adult; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D006801:Humans; D008875:Middle Aged; D008969:Molecular Sequence Data; D009426:Netherlands / Q000453:epidemiology; D027383:Papillomaviridae / Q000235:genetics*; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000821:virology; D016133:Polymerase Chain Reaction; D015995:Prevalence; D011446:Prospective Studies; D014412:Tumor Virus Infections / Q000453:epidemiology* / Q000821:virology; D002578:Uterine Cervical Dysplasia / Q000150:complications* / Q000473:pathology / Q000628:therapy; D002583:Uterine Cervical Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy
D004279:DNA, Viral