Liver cell culture methods for measuring DNA alterations produced by chemicals and radiation.
Liver culture systems, both primary cultures of hepatocytes and replicating cell lines, can be used in a variety of ways to study the DNA-damaging effects of chemicals and radiation. The present report describes some of the available methods and their interpretation.
Williams
G M
GM
American Health Foundation, Valhalla, NY, USA.
D000818:Animals; D015197:Carcinogenicity Tests; D002460:Cell Line; D002478:Cells, Cultured; D004249:DNA Damage; D006801:Humans; D008099:Liver / Q000166:cytology* / Q000187:drug effects / Q000528:radiation effects; D009152:Mutagenicity Tests; D018384:Oxidative Stress; D051381:Rats; D018675:Toxicity Tests; D014466:Ultraviolet Rays; D015262:Xenobiotics / Q000633:toxicity*
D015262:Xenobiotics