[The results of experimental study of phytoecdysteroids as erythropoiesis stimulators in laboratory animals].
Phytoecdysteroids alpha-ecdysone, 2-desoxyecdysterone, ecdysterone, sileneoside A, and turkesterone isolated from Rhaponticum carthamoides (Willd.) IIjin, Silene brahuica Boiss and Ajuga turkestanica (Rgl.) Repeated administration of brig increased the content of erythrocytes and hemoglobin in the blood of intact rats. The most active of them--ecdysterone, sileneoside A, and, particularly turkesterone, cause also a marked effect on red blood regeneration in hemotoxic phenylhydrazine anemia. In its capacity for simulating erythropoiesis turkesterone resembles the well-known steroidal anabolic drug nerobol.
Syrov
V N
VN
Nasyrova
S S
SS
Khushbaktova
Z A
ZA
D045930:Anabolic Agents / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D000743:Anemia, Hemolytic / Q000188:drug therapy; D000818:Animals; D004441:Ecdysterone / Q000008:administration & dosage / Q000031:analogs & derivatives / Q000494:pharmacology / Q000627:therapeutic use; D004906:Erythrocyte Count / Q000187:drug effects; D004920:Erythropoiesis / Q000187:drug effects*; D006454:Hemoglobins / Q000378:metabolism; D008696:Methandrostenolone / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D010659:Phenylhydrazines / Q000633:toxicity; D010840:Phytosterols / Q000008:administration & dosage / Q000494:pharmacology* / Q000627:therapeutic use; D051381:Rats; D012015:Reference Standards; D013329:Structure-Activity Relationship
D045930:Anabolic Agents; D006454:Hemoglobins; D010659:Phenylhydrazines; D010840:Phytosterols; C030299:phenylhydrazine; D004441:Ecdysterone; C017787:turkesterone; D008696:Methandrostenolone