title: Distribution of HLA-DQ alpha and polymarker (LDLR, GC, GYPA, HBGG, and D7S8) alleles in Arab and Pakistani populations living in Abu Dhabi, United Arab Emirates.
abstract: Randomly collected blood samples from 100 Arabs and 100 Pakistanis residing in Abu Dhabi were analyzed using the HLA-DQ alpha and polymarker (LDLR, GC, GYPA, HBGG, D7S8) PCR based reverse dot blot systems. Allelic frequencies for each allele and observed heterozygosity for each locus were calculated. Departures from Hardy-Weinberg expectations (HWE) were determined using the unbiased estimate of the expected homozygote/ heterozygote frequencies, the likelihood ratio test and the exact test. No significant departures from HWE expectations were detected.
authors.affiliation: Indianapolis-Marion County Forensic Services Agency, IN, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Tahir
authors.forename: J
authors.initials: J
authors.lastname: Caruso
authors.forename: B
authors.initials: B
authors.lastname: Budowle
authors.forename: N
authors.initials: N
authors.lastname: Aziz
authors.forename: G E
authors.initials: GE
authors.lastname: Novick
mesh_terms: D001798:Blood Proteins / Q000235:genetics*; D004247:DNA / Q000097:blood*; D005784:Gene Amplification; D005787:Gene Frequency; D005819:Genetic Markers; D005838:Genotype; D006683:HLA-DQ Antigens / Q000235:genetics*; D059848:HLA-DQ alpha-Chains; D006801:Humans; D016013:Likelihood Functions; D010154:Pakistan / Q000453:epidemiology; D016133:Polymerase Chain Reaction; D011897:Random Allocation; D012529:Saudi Arabia / Q000453:epidemiology; D014479:United Arab Emirates; D044465:White People / Q000235:genetics*
chemical_list: D001798:Blood Proteins; D005819:Genetic Markers; D006683:HLA-DQ Antigens; D059848:HLA-DQ alpha-Chains; C069050:HLA-DQA1 antigen; D004247:DNA