title: [Prognostic significance of desmoplasia in breast carcinoma. A preliminary clinical study].
abstract: This study carried on 61 patients with breast cancer confirmed the biological assumption of a higher malignancy in tumors with strong desmoplastic reaction. Patients in stage II A, II B and III presenting a marked desmoplastic reaction have a shorter DFS (disease free survival). Therefore, desmoplastic reaction may be considered a marker of local malignancy and metastatic process.
authors.affiliation: III Clinica Chirurgica Generale e Terapia Chirurgica, Università degli Studi La Sepienza, Roma.
authors.forename: S
authors.initials: S
authors.lastname: Mezi
authors.forename: G
authors.initials: G
authors.lastname: Aloise
authors.forename: A
authors.initials: A
authors.lastname: Marzullo
authors.forename: P
authors.initials: P
authors.lastname: Marchei
authors.forename: A
authors.initials: A
authors.lastname: Di Benedetto
authors.forename: A
authors.initials: A
authors.lastname: Modica
authors.forename: F
authors.initials: F
authors.lastname: Vasaturo
authors.forename: M
authors.initials: M
authors.lastname: Modesti
mesh_terms: D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000473:pathology; D011379:Prognosis; D013997:Time Factors
chemical_list: D014408:Biomarkers, Tumor