title: Complete nucleotide sequence of the HLA-DRB1 *1302 allele.
abstract: Sequencing studies of HLA class II molecules have focused almost exclusively on its exon 2. The complete cDNA sequence of the DRB*1302 allele is reported here for the first time. A conservative polymorphism was detected outside the exon 2 at residue 206; these changes can only be recorded if complete cDNA sequences are studied, and may be of value in drawing evolutive inferences.
authors.affiliation: Hospital Universitario 12 de Octubre, Universidad Complutense, Madrid, Spain.
authors.forename: N
authors.initials: N
authors.lastname: Martinez-Quiles
authors.forename: J M
authors.initials: JM
authors.lastname: Martin-Villa
authors.forename: J
authors.initials: J
authors.lastname: Martinez-Laso
authors.forename: S
authors.initials: S
authors.lastname: Ferre-Lopez
authors.forename: M
authors.initials: M
authors.lastname: Alvarez
authors.forename: E
authors.initials: E
authors.lastname: Gomez-Casado
authors.forename: M D
authors.initials: MD
authors.lastname: de Juan
authors.forename: A
authors.initials: A
authors.lastname: Arnaiz-Villena
mesh_terms: D001483:Base Sequence; D018076:DNA, Complementary / Q000235:genetics; D005091:Exons / Q000235:genetics; D005260:Female; D005802:Genes, MHC Class II / Q000235:genetics*; D006684:HLA-DR Antigens / Q000032:analysis / Q000235:genetics*; D059810:HLA-DR Serological Subtypes; D059811:HLA-DRB1 Chains; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000235:genetics / Q000276:immunology; D008297:Male; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic; D017422:Sequence Analysis, DNA
chemical_list: D018076:DNA, Complementary; D006684:HLA-DR Antigens; D059810:HLA-DR Serological Subtypes; C097337:HLA-DR13 antigen; D059811:HLA-DRB1 Chains