Prevention of the development of murine systemic lupus erythematosus (SLE)-like diseases by the malononitrilamides MNA 279 and MNA 715.
Schorlemmer
H U
HU
Research Laboratories Hoechst Marion Roussell (HMR), Marburg, Germany.
Bartlett
R R
RR
D000375:Aging; D000480:Alkynes; D000818:Animals; D001327:Autoimmune Diseases / Q000209:etiology / Q000517:prevention & control; D005260:Female; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D007555:Isoxazoles; D007700:Kinetics; D008180:Lupus Erythematosus, Systemic / Q000517:prevention & control*; D008198:Lymph Nodes / Q000473:pathology; D051379:Mice; D008811:Mice, Inbred DBA; D009570:Nitriles / Q000627:therapeutic use*; D013154:Spleen / Q000637:transplantation; D013163:Splenomegaly / Q000517:prevention & control
D000480:Alkynes; D007166:Immunosuppressive Agents; D007555:Isoxazoles; D009570:Nitriles; C102911:X 910279; C115284:2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide