title: The development of congestive cardiac failure in a patient with hairy cell leukemia treated with 2-chlorodeoxyadenosine.
abstract: Deoxyadenosines are closely related to adenosine and as such, may interfere with the cardiac adenylate cyclase pathway resulting in cardiac dysfunction. We report a rare case of a 42 year old man who developed transient cardiac failure following treatment with 2-CDA for hairy cell leukemia.
authors.affiliation: Division of Medicine, Roswell Park Cancer Institute, Buffalo, New York, USA.
authors.forename: B
authors.initials: B
authors.lastname: Koczwara
authors.forename: E
authors.initials: E
authors.lastname: Spangenthal
authors.forename: S H
authors.initials: SH
authors.lastname: Bernstein
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D017338:Cladribine / Q000009:adverse effects* / Q000627:therapeutic use*; D006333:Heart Failure / Q000139:chemically induced*; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000150:complications / Q000188:drug therapy*; D008297:Male
chemical_list: D000970:Antineoplastic Agents; D017338:Cladribine