title: Effect of ingested sodium bicarbonate on muscle force, fatigue, and recovery.
abstract: The influence of acute ingestion of NaHCO3 on fatigue and recovery of teh quadriceps femoris muscle after exercise was studied in six healthy male subjects. A bicycle ergometer was used for exercising under three loading conditions: test A, load corresponding to maximal oxygen consumption; test B, load in test A + 17%; test C, load in test B but performed 1 h after acute ingestion of NaHCO3. Functional electrical stimulation (FES) was applied to provoke isometric contraction of the quadriceps femoris. The resulting knee torque was monitored during fatigue (2-min chronic FES) and recovery (10-s FES every 10 min, for 40 min). Quadriceps torques were higher in the presence of NaHCO3 (P < 0.05): with NaHCO3 the peak, residual, and recovery (after 40 min) normalized torques were, respectively, 0.68 +/- 0.05 (SD), 0.58 +/- 0.05, and 0.73 +/- 0.05; without NaHCO3 the values were 0.45 +/- 0.04, 0.30 +/- 0.06, and 0.63 +/- 0.06. The increased torques obtained after acute ingestion of NaHCO3 indicate the possible existence of improved nonoxidative glycolysis in isometric contraction, resulting in reduced fatigue and enhanced recovery.
authors.affiliation: Department of Biomedical Engineering, Technion-Israel Institute of Technology, Haifa 32000, Israel.
authors.forename: O
authors.initials: O
authors.lastname: Verbitsky
authors.forename: J
authors.initials: J
authors.lastname: Mizrahi
authors.forename: M
authors.initials: M
authors.lastname: Levin
authors.forename: E
authors.initials: E
authors.lastname: Isakov
mesh_terms: D000284:Administration, Oral; D000328:Adult; D004558:Electric Stimulation; D006801:Humans; D007537:Isometric Contraction; D008297:Male; D018763:Muscle Fatigue / Q000187:drug effects*; D009132:Muscles / Q000187:drug effects* / Q000502:physiology*; D017693:Sodium Bicarbonate / Q000494:pharmacology*; D013848:Thigh; D019415:Torque
chemical_list: D017693:Sodium Bicarbonate