title: Stability of C3 convertase in the rat classical complement pathway.
abstract: It has been reported that rat serum complement causes efficient hemolysis of antibody-sensitized sheep erythrocytes (EA) at 20 C but not at 37 C. In connection with this, we demonstrated that C3 convertase of rat complement was significantly unstable at 37 C using purified components of rat complement.
authors.affiliation: Department of Molecular Biology, Nagoya City University School of Medicine, Aichi, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Naito
authors.forename: H
authors.initials: H
authors.lastname: Okada
mesh_terms: D000818:Animals; D003175:Complement C2 / Q000302:isolation & purification* / Q000378:metabolism; D050577:Complement C3-C5 Convertases / Q000378:metabolism*; D006168:Guinea Pigs; D006461:Hemolysis; D051381:Rats; D013696:Temperature
chemical_list: D003175:Complement C2; D050577:Complement C3-C5 Convertases