title: Noninvasive risk stratification in unstable coronary artery disease: exercise test and biochemical markers. FRISC Study Group.
abstract: Early risk assessment is essential for the application of appropriate treatment and further management in patients with unstable coronary artery disease, i.e., unstable angina or non-Q-wave myocardial infarction. In this article, the use of exercise testing and biochemical markers for identification of high- and low-risk patients is discussed, with special reference to experiences from the FRISC (Fragmin During Instability in Coronary Artery Disease) trial. It is concluded that a symptom-limited predischarge exercise test (provided all relevant information obtained is considered) and determination of troponin T are inexpensive, widely applicable, and useful methods for early risk stratification in both men and women after an episode of unstable coronary artery disease.
authors.affiliation: Department of Cardiology, University of Uppsala, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Lindahl
authors.forename: B
authors.initials: B
authors.lastname: Andrén
authors.forename: J
authors.initials: J
authors.lastname: Ohlsson
authors.forename: P
authors.initials: P
authors.lastname: Venge
authors.forename: L
authors.initials: L
authors.lastname: Wallentin
mesh_terms: D015415:Biomarkers / Q000097:blood; D003327:Coronary Disease / Q000175:diagnosis* / Q000453:epidemiology / Q000401:mortality; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000175:diagnosis / Q000401:mortality; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D018570:Risk Assessment; D016019:Survival Analysis; D014336:Troponin / Q000097:blood; D020107:Troponin T
chemical_list: D015415:Biomarkers; D014336:Troponin; D020107:Troponin T