Percutaneous varicocele embolization versus surgical ligation for the treatment of infertility: changes in seminal parameters and pregnancy outcomes.
OBJECTIVE
To compare the success of percutaneous varicocele embolization to surgical ligation with regard to changes in semen characteristics and pregnancy outcome.


METHODS
Infertility records from 346 men who underwent correction of their varicocele for infertility (surgical ligation 149; embolization 197) were reviewed retrospectively. Preprocedural and postprocedural semen analyses and pregnancy outcomes were obtained with use of chart and telephone follow-up.


RESULTS
In men who successfully impregnated their partners, there were significant improvements in sperm density, percent total improvement, motility, and progression. Postprocedural (embolization vs surgery) percentage increases in seminal parameters were density, 156.8% versus 138.5%; total, 168.8% versus 157.91%; and motility, 2.7% versus 3.2%. The percent of individuals who had a change in sperm progression was 31% versus 41%. There was no statistical difference between the techniques based on t tests. The pregnancy rates were similar for the two groups, 39% and 34% for embolization and surgery, respectively.


CONCLUSIONS
There is no significant statistical difference in seminal values or pregnancy outcome between the two techniques.
Shlansky-Goldberg
R D
RD
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104, USA.
VanArsdalen
K N
KN
Rutter
C M
CM
Soulen
M C
MC
Haskal
Z J
ZJ
Baum
R A
RA
Redd
D C
DC
Cope
C
C
Pentecost
M J
MJ
D000328:Adult; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000379:methods; D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000209:etiology*; D008026:Ligation; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011677:Punctures; D012189:Retrospective Studies; D013076:Sperm Count; D013081:Sperm Motility; D014646:Varicocele / Q000150:complications / Q000628:therapy*