title: N1-Hetaryl substituted pyridine- and pyrazinecarboxamidrazones with antimycobacterial activity.
abstract: A series of amidrazones was prepared and characterized by 1H NMR and mass spectroscopy. The substances were tested against M. tuberculosis, M. avium, M. intracellulare, and M. lufu. Compounds 11-13 exhibit a satisfactory inhibition of mycobacteria.
authors.affiliation: Institut für Pharmazeutische Chemie, Halle.
authors.forename: D
authors.initials: D
authors.lastname: Ranft
authors.forename: G
authors.initials: G
authors.lastname: Lehwark-Yvetot
authors.forename: K J
authors.initials: KJ
authors.lastname: Schaper
authors.forename: A
authors.initials: A
authors.lastname: Büge
mesh_terms: D000995:Antitubercular Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D009161:Mycobacterium / Q000187:drug effects* / Q000254:growth & development; D009162:Mycobacterium avium / Q000187:drug effects; D015269:Mycobacterium avium Complex / Q000187:drug effects; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D011719:Pyrazines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011725:Pyridines / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013329:Structure-Activity Relationship
chemical_list: D000995:Antitubercular Agents; D011719:Pyrazines; D011725:Pyridines