[The role of free radical processes in the uterus--placenta--fetus system during adaptation to interval hypoxia].
The impact of adaptation to interval normobaric hypoxia on free radical-mediated processes was studied in pregnant women at abdominal delivery. The content of the material reacting with thiobarbituric acid, the generation of active oxygen forms (peroxide-induced, luminol-dependent chemiluminescence) and superoxide scavenging activity were evaluated in maternal venous plasma, umbilical plasma, and placenta. The findings suggest that interval hypoxic training of pregnant women produces antioxidative effects not only on the maternal organism, but also on the fetus and placenta. Thus, regulation and optimization of free radical-mediated processes in the mother-placenta-fetus system are a mechanism underlying the beneficial effects of interval hypoxic training.
Piliavskaia
A N
AN
Adiiatulin
A I
AI
Tkachuk
E N
EN
Gluiaeva
N V
NV
D000222:Adaptation, Physiological; D000328:Adult; D005260:Female; D005333:Fetus / Q000502:physiology*; D005609:Free Radicals; D006801:Humans; D010100:Oxygen / Q000502:physiology*; D010920:Placenta / Q000502:physiology*; D011247:Pregnancy; D014599:Uterus / Q000502:physiology*
D005609:Free Radicals; D010100:Oxygen