[Cyclophosphane in the treatment of trophic ulcers of lower extremities with allergic and autoimmune components].
In 36 patients with varicose-trophic ulcers of the lower extremities with marked allergic and autoimmune components use of low frequency ultrasound through 0.02% solution of chlorhexidine and 0.2% cyclophosphamide made it possible to diminish allergic dermatitis and eczema after 5 or 7 procedures. The ulcers cleaned in 8-13 days (sometimes, in 14-18 days). In 27 patients surgical correction of venous blood flow was performed after the sanatation and autodermoplasty of the ulcers. There were no recurrences in the long-term period (up to 2 years).
Khokhlov
A M
AM
Khanin
A G
AG
D000368:Aged; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D002710:Chlorhexidine / Q000008:administration & dosage*; D003520:Cyclophosphamide / Q000008:administration & dosage*; D003876:Dermatitis, Atopic / Q000188:drug therapy; D004485:Eczema / Q000188:drug therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D016038:Skin Transplantation; D013997:Time Factors; D014464:Ultrasonic Therapy; D014647:Varicose Ulcer / Q000188:drug therapy* / Q000276:immunology / Q000601:surgery
D000891:Anti-Infective Agents, Local; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D002710:Chlorhexidine