Perfusion MRI in normal and abnormal pituitary gland. A preliminary study.
Perfusion MRI (magnetic resonance imaging) of the pituitary gland was performed in 20 healthy volunteers and 63 patients with various lesions involving the pituitary gland. All patients underwent sequential contrast-enhanced MRI using spoiled gradient recalled sequences with high temporal resolution (7 seconds). Four pituitary areas (pituitary stalk, posterior lobe, postero-superior, and antero-inferior adenohypophysis) were tested with a selected region of interest. Maximal contrast percentual variation was calculated. The timing of enhancement in normal patients matched perfectly with normal pituitary vascularization. Abnormal timing in pathological condition was investigated.
Manfré
L
L
Department of Radiology P. Cignolini, University of Palermo, Italy.
Midiri
M
M
Rosato
F
F
Janni
A
A
Lagalla
R
R
D000236:Adenoma / Q000098:blood supply* / Q000175:diagnosis; D000324:Adrenocorticotropic Hormone / Q000378:metabolism*; D003287:Contrast Media; D003937:Diagnosis, Differential; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D010900:Pituitary Diseases / Q000175:diagnosis; D010902:Pituitary Gland / Q000098:blood supply*; D010911:Pituitary Neoplasms / Q000098:blood supply* / Q000175:diagnosis; D015175:Prolactinoma / Q000098:blood supply* / Q000175:diagnosis; D012016:Reference Values; D012039:Regional Blood Flow / Q000502:physiology
D003287:Contrast Media; D000324:Adrenocorticotropic Hormone; D019786:Gadolinium DTPA