Computed axial tomographic scan measurement of abdominal fat distribution and its correlation with anthropometry and insulin secretion in healthy Asian Indians.
Asian Indians have high insulin resistance, hyperinsulinemia, a high prevalence of diabetes, and a high waist to hip ratio (WHR), although the rate of obesity is low. WHR and visceral fat (VF) are highly correlated, and both are associated with insulin resistance. This study was performed to determine the normal ranges of abdominal fat distribution (subcutaneous [SF] and VF) in nondiabetic South Indians and also to study its correlations with WHR, plasma insulin, and metabolic profiles. Fat areas were measured by computed axial tomographic scan at the L4 to L5 level. Mean areas of SF and VF in men and women in this study were similar to the values in white populations. Women had significantly less VF than men. Gender differences were observed in the contribution of fat areas to anthropometric, hormonal, and metabolic variables. In general, in men, total fat (TF) area showed significant independent correlation with body mass index (BMI), WHR, and total cholesterol, and VF correlated with insulin secretion. In women, TF and BMI were correlated and SF showed a correlation with total cholesterol. Insulin secretion in women did not show a correlation with fat areas.
Snehalatha
C
C
Diabetes Research Centre, Royapuram, Madras, India.
Ramachandran
A
A
Satyavani
K
K
Vallabi
M Y
MY
Viswanathan
V
V
D000005:Abdomen; D000273:Adipose Tissue / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D000328:Adult; D000704:Analysis of Variance; D000886:Anthropometry / Q000379:methods; D001786:Blood Glucose / Q000378:metabolism; D001824:Body Constitution; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D006801:Humans; D007194:India; D007328:Insulin / Q000097:blood / Q000378:metabolism*; D000078790:Insulin Secretion; D008297:Male; D010725:Phosphocreatine / Q000097:blood; D012044:Regression Analysis; D014057:Tomography, X-Ray Computed / Q000379:methods; D014280:Triglycerides / Q000097:blood; D044465:White People
D001786:Blood Glucose; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D007328:Insulin; D014280:Triglycerides; D010725:Phosphocreatine; D002784:Cholesterol