title: Laser-induced thermal lesions in the human brain: short- and long-term appearance on MRI.
abstract: OBJECTIVE
  The purpose of our study was to investigate with MRI the development of thermal lesions in the human brain up to almost 4 years after laser-induced interstitial thermotherapy (LITT).
  
  
  METHODS
  Eighteen patients with brain tumors who underwent LITT entered the study.
  
  
  RESULTS
  In all patients the acute lesion comprised five concentric zones that showed reverse signal intensities on T1- versus T2-weighted images. Lesion development over time was uniform in 89% of the lesions. In two cases variations were observed.
  
  
  CONCLUSIONS
  The results of our MR follow-up studies showed that post-LITT, laser-induced lesions will shrink exponentially after an initial expansion without any pseudocystic effects.
authors.affiliation: Institute of Diagnostic Radiology, Heinrich Heine University, Düsseldorf, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Schwabe
authors.forename: T
authors.initials: T
authors.lastname: Kahn
authors.forename: T
authors.initials: T
authors.lastname: Harth
authors.forename: F
authors.initials: F
authors.lastname: Ulrich
authors.forename: H J
authors.initials: HJ
authors.lastname: Schwarzmaier
mesh_terms: D000328:Adult; D000368:Aged; D001254:Astrocytoma / Q000628:therapy; D001921:Brain / Q000473:pathology*; D001929:Brain Edema / Q000473:pathology; D001932:Brain Neoplasms / Q000628:therapy*; D003287:Contrast Media; D005260:Female; D005500:Follow-Up Studies; D005682:Gadolinium; D019786:Gadolinium DTPA; D005910:Glioma / Q000628:therapy; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D017075:Laser Coagulation; D053685:Laser Therapy; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives; D013238:Stereotaxic Techniques; D014945:Wound Healing
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA