The case for sunscreens. A review of their use in preventing actinic damage and neoplasia.
BACKGROUND
Recent controversy surrounding sunscreens has stimulated a reexamination of their use. The purposes of this article are to weigh the evidence regarding the value of sunscreens in preventing actinic damage and neoplasia and to evaluate the merit of objections that have been raised against their use for this purpose. Scientific aspects of damage from UV light, neoplasia, and sunscreens are reviewed. The value of sunscreen use in preventing actinic damage is discussed and a number of sunscreen controversies are revisited.


METHODS
The evidence favors the safety and efficacy of sunscreens for the prevention of actinic damage, melanoma, and nonmelanoma skin cancer.


CONCLUSIONS
Sunscreens continue to be a practical and useful tool for the prevention of actinic damage and neoplasia.
Naylor
M F
MF
Department of Dermatology, College of Medicine, University of Oklahoma, Oklahoma City, USA.
Farmer
K C
KC
D000818:Animals; D006801:Humans; D007108:Immune Tolerance / Q000187:drug effects / Q000528:radiation effects; D008545:Melanoma / Q000517:prevention & control*; D009153:Mutagens / Q000009:adverse effects; D009381:Neoplasms, Radiation-Induced / Q000517:prevention & control*; D012878:Skin Neoplasms / Q000517:prevention & control*; D013471:Sunburn / Q000517:prevention & control*; D013473:Sunscreening Agents / Q000009:adverse effects / Q000627:therapeutic use*; D014466:Ultraviolet Rays / Q000009:adverse effects*
D009153:Mutagens; D013473:Sunscreening Agents