title: Interspecies sharing of two distinct nonstructural protein 1 alleles among human and animal rotaviruses as revealed by dot blot hybridization.
abstract: The distribution of the nonstructural protein 1 (NSP1) alleles from human strain AU-1 and canine strain K9 among rotaviruses of human, feline, canine, bovine, and simian origin was studied by a dot blot hybridization assay. Human and feline strains belonging to the AU-1 genogroup had the same NSP1 allele, while canine and feline strains belonging to the canine-feline genogroup shared another NSP1 allele. This canine-feline NSP1 allele had a significant level of homology with the NSP1 of rhesus rotavirus strain MMU18006.
authors.affiliation: Department of Microbiology, Akita University School of Medicine, Hondo, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Fujiwara
authors.forename: O
authors.initials: O
authors.lastname: Nakagomi
mesh_terms: D000483:Alleles; D000818:Animals; D000956:Antigens, Viral; D002213:Capsid / Q000235:genetics; D036022:Capsid Proteins; D002415:Cats; D002417:Cattle; D004285:Dogs; D006801:Humans; D008969:Molecular Sequence Data; D009693:Nucleic Acid Hybridization; D012401:Rotavirus / Q000145:classification* / Q000235:genetics; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity; D017361:Viral Nonstructural Proteins / Q000235:genetics*
chemical_list: D000956:Antigens, Viral; D036022:Capsid Proteins; C060339:VP4 protein, Rotavirus; C050779:VP7 protein, Rotavirus; D017361:Viral Nonstructural Proteins; C104282:nsp1 protein, Rotavirus