Nerve expansion in nerve regeneration: effect of time on induction of ornithine decarboxylase and Schwann cell proliferation.
We studied the effect of initiation time of nerve expansion after nerve transection on the induction of ODC activity and Schwann cell proliferation in nerve tissue under Wallerian degeneration. The levels of ODC activity and Schwann cell proliferation decreased as the initiation time of nerve expansion was delayed after nerve transection, and peak levels of ODC activity following nerve expansion preceded peak levels of Schwann cell proliferation.
Ohkaya
S
S
Department of Orthopedic Surgery, Faculty of Medicine, Mie University, Japan.
Hibasami
H
H
Hirata
H
H
Sasaki
H
H
Morita
A
A
Matsumoto
M
M
Uchida
A
A
Nakashima
K
K
D000818:Animals; D002455:Cell Division; D003714:Denervation; D004790:Enzyme Induction; D008297:Male; D009416:Nerve Regeneration / Q000502:physiology*; D009417:Nerve Tissue / Q000503:physiopathology*; D009955:Ornithine Decarboxylase / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D012583:Schwann Cells / Q000166:cytology*; D013997:Time Factors; D014855:Wallerian Degeneration / Q000502:physiology
D009955:Ornithine Decarboxylase