Reduction of nitrazepam by Clostridium leptum, a nitroreductase-producing bacterium isolated from the human intestinal tract.
Rafii
F
F
Division of Microbiology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, Arkansas 72079, USA.
Sutherland
J B
JB
Hansen
E B
EB
Cerniglia
C E
CE
D003013:Clostridium / Q000378:metabolism*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006993:Hypnotics and Sedatives / Q000378:metabolism*; D007422:Intestines / Q000382:microbiology*; D009567:Nitrazepam / Q000378:metabolism*; D009601:Nitroreductases / Q000378:metabolism*; D010084:Oxidation-Reduction
D006993:Hypnotics and Sedatives; D009567:Nitrazepam; D009601:Nitroreductases