title: [The diagnosis and clinical characteristics of cytomegalovirus infection in HIV-infected subjects].
abstract: Out of 180 HIV carriers active cytomegalovirus (CMV) infection was found in 30 patients, in 16 cases the infection manifested clinically. Most of the latter were patients with HIV infection IIIb or IIIc stage against persistent lowering of CD4-lymphocyte count under 100/mm3. Active CMV infection may be determined most significantly by the following criteria: high or moderate concentrations of CMV DNA in the blood, low concentrations of blood CMV DNA in the presence of long-term (at least 3 months) persistence of anti-CMV IgM and isolation of urinary CMV. CMV infection manifested usually as a generalized disease with typical signs of retinitis, myelitis, erosive-ulcerative colitis. Most patients had thrombocytopenia, functionally defective platelets. CNS involvement predicts poor prognosis in CMV-infected HIV carriers.
authors.forename: V I
authors.initials: VI
authors.lastname: Shakhgil'dian
authors.forename: A V
authors.initials: AV
authors.lastname: Kravchenko
authors.forename: O Iu
authors.initials: OIu
authors.lastname: Shipulina
authors.forename: N R
authors.initials: NR
authors.lastname: Marchenko
authors.forename: T N
authors.initials: TN
authors.lastname: Ermak
authors.forename: O G
authors.initials: OG
authors.lastname: Iurin
authors.forename: V M
authors.initials: VM
authors.lastname: Stakhanova
authors.forename: Iu G
authors.initials: IuG
authors.lastname: Parkhomenko
authors.forename: N V
authors.initials: NV
authors.lastname: Karazhas
authors.forename: L F
authors.initials: LF
authors.lastname: Evseeva
authors.forename: B M
authors.initials: BM
authors.lastname: Gruzdev
authors.forename: V V
authors.initials: VV
authors.lastname: Pokrovskiĭ
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000097:blood / Q000145:classification / Q000175:diagnosis* / Q000821:virology; D000328:Adult; D000918:Antibody Specificity; D015703:Antigens, CD / Q000097:blood; D000944:Antigens, Differentiation, B-Lymphocyte / Q000097:blood; D018791:CD4 Lymphocyte Count; D018414:CD8-Positive T-Lymphocytes / Q000166:cytology; D015815:Cell Adhesion Molecules; D003587:Cytomegalovirus / Q000235:genetics / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000097:blood / Q000175:diagnosis* / Q000821:virology; D004279:DNA, Viral / Q000097:blood; D005260:Female; D015483:HIV Antibodies / Q000097:blood; D015497:HIV-1; D006801:Humans; D037102:Lectins; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D051918:Sialic Acid Binding Ig-like Lectin 2; D014556:Urine / Q000821:virology
chemical_list: D015703:Antigens, CD; D000944:Antigens, Differentiation, B-Lymphocyte; C497867:CD22 protein, human; D015815:Cell Adhesion Molecules; D004279:DNA, Viral; D015483:HIV Antibodies; D037102:Lectins; D051918:Sialic Acid Binding Ig-like Lectin 2