Neuromagnetic fields reveal cortical plasticity when learning an auditory discrimination task.
Auditory evoked neuromagnetic fields of the primary and association auditory cortices were recorded while subjects learned to discriminate small differences in frequency and intensity between two consecutive tones. When discrimination was no better than chance, evoked field patterns across the scalp manifested no significant differences between correct and incorrect responses. However, when performance was correct on at least 75% of the trials, the spatial pattern of magnetic field differed significantly between correct and incorrect responses during the first 70 ms following the onset of the second tone. In this respect, the magnetic field pattern predicted when the subject would make an incorrect judgment more than 100 ms prior to indicating the judgment by a button press. One subject improved discrimination for much smaller differences between stimuli after 200 h of training. Evidence of cortical plasticity with improved discrimination is provided by an accompanying decrease of the relative magnetic field amplitude of the 100 ms response components in the primary and association auditory cortices.
Cansino
S
S
Laboratory of Cognitive Psychophysiology, Psychology Faculty, National Autonomous University of Mexico, Mexico City, DF. selene@servidor.unam.mx
Williamson
S J
SJ
D000161:Acoustic Stimulation; D000328:Adult; D001303:Auditory Cortex / Q000033:anatomy & histology / Q000502:physiology; D002540:Cerebral Cortex / Q000502:physiology*; D015350:Contrast Sensitivity; D004193:Discrimination Learning / Q000502:physiology*; D005260:Female; D006801:Humans; D015225:Magnetoencephalography; D008297:Male; D008875:Middle Aged; D009473:Neuronal Plasticity / Q000502:physiology*; D010364:Pattern Recognition, Visual / Q000502:physiology