title: A study of clinical and aetiological factors and possible associations of lichen sclerosus in males.
abstract: Lichen sclerosus is a chronic skin condition with a predilection for the genital area. In the present study, 35 male patients with lichen sclerosus were interviewed and examined. Blood screens were performed and histology was requested if not already performed. The findings indicate that lichen sclerosus in males exists as a spectrum of disease, ranging from a mild form with white plaques and few symptoms to a severe form with inflammation, atrophy and scarring with possible urological consequences. In many areas it differs from the condition in females; the association with autoimmune disease is weaker and there is less perianal and extragenital involvement. The association with malignancy in males is of lesser significance than initially believed.
authors.affiliation: Department of Dermatology, Amersham Hospital, United Kingdom.
authors.forename: T K
authors.initials: TK
authors.lastname: Lipscombe
authors.forename: J
authors.initials: J
authors.lastname: Wayte
authors.forename: F
authors.initials: F
authors.lastname: Wojnarowska
authors.forename: P
authors.initials: P
authors.lastname: Marren
authors.forename: G
authors.initials: G
authors.lastname: Luzzi
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D001327:Autoimmune Diseases / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D002648:Child; D003876:Dermatitis, Atopic / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D006801:Humans; D018459:Lichen Sclerosus et Atrophicus / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010808:Physical Examination; D012307:Risk Factors; D006113:United Kingdom / Q000453:epidemiology