title: Unilateral multiple adenolymphomas originating in the parotid gland: a clinicopathological study.
abstract: The validity of Seifert's hypothesis about growth pattern of adenolymphomas has been evaluated in three of five patients with adenolymphomas of the parotid gland, who at the time of a parotidectomy, were found to have multiple unilateral adenolymphomas in the intraglandular lymph nodes. This evaluation, which was based on assessing the epithelial: lymphoid tissue ratio in excised adenolymphomas and the growth in tumor size, showed that there was no association between the histological changes in the epithelial:lymphoid tissue and the tumor size. Adenolymphomas seem to have no consistent growth pattern and develop independently. However, as multiple tumors were detected histopathologically in lymph nodes as small as 5 mm in diameter the importance of a detailed examination of patients with adenolymphomas is stressed, so that other tumours are not overlooked.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Kitasato University, School of Medicine, Kanagawa, Japan.
authors.forename: E
authors.initials: E
authors.lastname: Uchinuma
authors.forename: N
authors.initials: N
authors.lastname: Shioya
mesh_terms: D000235:Adenolymphoma / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010306:Parotid Gland / Q000473:pathology*; D010307:Parotid Neoplasms / Q000473:pathology* / Q000601:surgery