[Correction of homeostasis disorders in postoperative patients with disseminated purulent peritonitis].
The results of the surgical treatment of 335 patients with a toxic stage of disseminated purulent peritonitis (DPP) are analysed. The toxic stage of the DPP is characterized by the pain syndrome, endotoxicosis, hypodynamic disorders of the blood circulation, respiration, and secondary immunodeficiency. The analgetic mixture of Analgin, Seduxen and No-Spa appeared to be more effective in pain relief than Promedol or Moradol. Slow body detoxication, long standing hypodynamic circulation disorders and immunodeficiency, high level of lethality (16.2%) are typical for patients with toxic stage of DPP treated with conventional therapy (infusion of desintoxic medicines, stimulated diuresis, peritoneal dialysis. The use of intravascular laser irradiation and hemosorption provides marked detoxic ating and immunostimulating effect. Hypoxia and circulatory hypodynamia and immunodeficiency are quickly eliminated with the use of hyperbaric oxygenation and immunocorrective medicines (T-activin, Decaris) and gives a chance to decrease mortality 2 times.
Ismaílov
I S
IS
Medical University, Baku, Azerbaijan.
D000700:Analgesics / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006706:Homeostasis; D006801:Humans; D006931:Hyperbaric Oxygenation; D006993:Hypnotics and Sedatives / Q000627:therapeutic use; D007022:Hypotension / Q000209:etiology / Q000628:therapy; D000860:Hypoxia / Q000209:etiology / Q000628:therapy; D007153:Immunologic Deficiency Syndromes / Q000209:etiology / Q000628:therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D010530:Peritoneal Dialysis; D010538:Peritonitis / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D011184:Postoperative Period; D013492:Suppuration / Q000601:surgery; D014665:Vasodilator Agents / Q000627:therapeutic use
D000700:Analgesics; D006993:Hypnotics and Sedatives; D007166:Immunosuppressive Agents; D014665:Vasodilator Agents