Separate and joint effects of marine oil and simvastatin in patients with combined hyperlipidemia.
Marine oil plus simvastatin is an effective therapy for improving serum triglycerides, non-high-density lipoprotein cholesterol, and high-density lipoprotein cholesterol in patients with combined hyperlipidemia. Concurrent administration does not attenuate the individual effects of either marine oil or simvastatin on the serum lipid profile.
Davidson
M H
MH
The Chicago Center for Clinical Research, Illinois 60610-4324, USA.
Macariola-Coad
J R
JR
McDonald
A M
AM
Maki
K C
KC
Hall
H A
HA
D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005260:Female; D005395:Fish Oils / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D006950:Hyperlipidemia, Familial Combined / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D008148:Lovastatin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D008297:Male; D019821:Simvastatin; D014280:Triglycerides / Q000097:blood
D005395:Fish Oils; D000960:Hypolipidemic Agents; D014280:Triglycerides; D008148:Lovastatin; D019821:Simvastatin