[Contemporary views on the pathogenesis and possible prophylaxis of age related cataracts].
In this review the role of UVB/290-320 nm/ and visible light radiation in generating of free radicals in the lens is described, which is the main factor leading to development of senile cataract. Also the mechanisms of antioxidant defence are presented especially glutathione and ascorbic acid. We review the literature connected with diet supplementation of antioxidants /vit. E, C, selenium/. According to actual theories the use of sun-glasses with UVB-filters, and antioxidant diet supplementation seems to be useful in prevention of age-related cataract.
Kałuzny
J J
JJ
Kliniki Okulistycznej AM w Bydgoszczy.
Kałuzny
J
J
D001205:Ascorbic Acid / Q000494:pharmacology; D002386:Cataract / Q000209:etiology* / Q000517:prevention & control*; D005139:Eyeglasses; D005527:Food, Fortified; D005609:Free Radicals / Q000009:adverse effects; D005978:Glutathione / Q000494:pharmacology; D006801:Humans; D007908:Lens, Crystalline / Q000187:drug effects / Q000528:radiation effects; D014466:Ultraviolet Rays / Q000009:adverse effects*
D005609:Free Radicals; D005978:Glutathione; D001205:Ascorbic Acid