Recurrent toxoplasmic retinochoroiditis. Significance of perilesional satellite dark dots seen by indocyanine green angiography.
OBJECTIVE
To suggest an explanation for the satellite dark dots seen by indocyanine green angiography (ICGA) around the main focus of a toxoplasmic retinochoroiditis.


METHODS
The authors analysed the evolution of ICG satellite dark dots in two cases of recurrent toxoplasmic retinochoroiditis receiving anti-toxoplasmic treatment not including corticosteroids.


RESULTS
Both patients had a recurrence on the peripheral aspect of scars from previous retinochoroiditis and were treated with pyrimethamine (50 mg/day) and sulfadiazine (4 g/day) for seven weeks. Resolution of satellite ICG dark dots was observed in both cases on the follow-up ICG angiogram performed at the end of treatment.


CONCLUSIONS
Resolution of ICG satellite dark dots after anti-toxoplasmic treatment not including corticosteroids tends to indicate that there is probably an infectious component in these hypofluorescent dots and that they probably do not represent a purely inflammatory perilesional reaction.
Bernasconi
O
O
Department of Ophthalmology, Hôpital Jules Gonin, University of Lausanne, Switzerland.
Auer
C
C
Herbort
C P
CP
D000328:Adult; D000792:Angiography; D000890:Anti-Infective Agents / Q000627:therapeutic use; D002825:Chorioretinitis / Q000188:drug therapy / Q000473:pathology*; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D011739:Pyrimethamine / Q000627:therapeutic use; D012008:Recurrence; D013411:Sulfadiazine / Q000627:therapeutic use; D014126:Toxoplasmosis, Ocular / Q000188:drug therapy / Q000473:pathology*; D014792:Visual Acuity
D000890:Anti-Infective Agents; D004396:Coloring Agents; D013411:Sulfadiazine; D007208:Indocyanine Green; D011739:Pyrimethamine