title: Early experience with the Norwood procedure.
abstract: The improved results of the Norwood procedure have recently stimulated its widespread adoption in many centres. Since 1993, 19 infants with hypoplastic left heart syndrome or similar conditions underwent a first-stage Norwood procedure. Circulatory arrest time was significantly reduced by using a modified repair of the aortic arch. The early mortality rate was 31.5% (n = 6). The addition of CO2 to the inspired gas mixture resulted in less early postoperative instability. Nine patients have subsequently undergone bidirectional cavopulmonary shunt and one fenestrated total cavopulmonary connection. Overall there have been five late deaths, two as result of failure of cavopulmonary operations. All the eight survivors are presently in good condition. One is awaiting bidirectional cavopulmonary shunt and the other seven total cavopulmonary connection. This early experience encourages the continued offering of the Norwood procedure to patients with hypoplastic left heart syndrome or its variants. Increasing experience with the perioperative care and a more careful evaluation before cavopulmonary operations may determine further improvement in the outcome.
authors.affiliation: Department of Cardiothoracic Surgery, National University Hospital Rigshospitalet, Copenhagen, Denmark.
authors.forename: S
authors.initials: S
authors.lastname: Conte
authors.forename: P B
authors.initials: PB
authors.lastname: Hansen
authors.forename: T
authors.initials: T
authors.lastname: Jensen
authors.forename: J R
authors.initials: JR
authors.lastname: Jacobsen
authors.forename: M
authors.initials: M
authors.lastname: Helvind
authors.forename: P
authors.initials: P
authors.lastname: Lauridsen
authors.forename: G
authors.initials: G
authors.lastname: Pettersson
mesh_terms: D001013:Aorta, Thoracic / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006324:Heart Arrest, Induced; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000401:mortality / Q000601:surgery*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011182:Postoperative Care / Q000379:methods; D011183:Postoperative Complications / Q000401:mortality / Q000601:surgery; D012086:Reoperation; D015996:Survival Rate; D013536:Suture Techniques