title: [The character of development of the immune response to sheep erythrocytes and parallel responses to exo- and endobiotics].
abstract: The immune response to sheep erythrocytes (SE) is usually used as the indicator system in screening of immunotropic compounds. We had shown earlier that a rapid immune reaction develops in response to a chemical compound (drug). It is characterized by an increase in the number of antigen-recognizing and antigen-producing lymphocytes and their blast forms, titers of antibodies specific of the introduced compound and endobiotics mobilized under its effect.
authors.forename: A A
authors.initials: AA
authors.lastname: Bykova
authors.forename: T A
authors.initials: TA
authors.lastname: Iushkova
mesh_terms: D000818:Animals; D000917:Antibody Formation / Q000187:drug effects / Q000276:immunology; D000918:Antibody Specificity / Q000187:drug effects* / Q000276:immunology; D000937:Antigen-Antibody Reactions / Q000276:immunology; D017690:Cell Transplantation; D004912:Erythrocytes / Q000166:cytology / Q000187:drug effects / Q000276:immunology*; D006241:Haptens / Q000008:administration & dosage / Q000633:toxicity; D007274:Injections, Intraperitoneal; D008213:Lymphocyte Activation / Q000187:drug effects; D008214:Lymphocytes / Q000166:cytology / Q000187:drug effects / Q000276:immunology / Q000378:metabolism; D051379:Mice; D012701:Serotonin / Q000378:metabolism; D012756:Sheep; D015262:Xenobiotics / Q000008:administration & dosage / Q000633:toxicity*
chemical_list: D006241:Haptens; D015262:Xenobiotics; D012701:Serotonin