[Measurements of ultrasound reflectivity of oculomotor muscles in endocrine orbitopathy].
BACKGROUND
In the course of Graves' disease (GD) the extraocular muscles become fibrotic after an acute inflammatory stage. Differentiation of these two stages is important for therapy.


METHODS
First, we examined the eye muscles of 30 healthy volunteers with the 10 MHz-B probe (Ultrascan) Digital B 2000) and then those of 20 patients with GD. The thickness was measured in the longitudinal displayed muscle always with the same gain. The amplitude of the highest inner muscle spikes expressed as a percentage of amplitude of retina-sclera spike provided the internal reflectivity. The stage of GD was determined by clinical signs.


RESULTS
In GD, thickness of inferior and medial rectus was significantly enhanced in both the inflammatory and fibrotic stages, while internal reflectivity was only significantly higher in the latter stage.


CONCLUSIONS
Ultrasound discriminates the acute from chronic course of GD in eye muscles and thus provides a very useful tool for making therapeutic decisions.
Sucker
J
J
Universitäts-Augenklinik Giessen.
Krzizok
T
T
D000328:Adult; D005355:Fibrosis; D006111:Graves Disease / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D009801:Oculomotor Muscles / Q000000981:diagnostic imaging*; D012016:Reference Values; D014463:Ultrasonography