title: Hypercalcemia and carcinoma of the penis.
abstract: Hypercalcemia is the most common metabolic disorder associated with malignancies. Squamous cell carcinoma of the penis is a tumor for which this abnormality has rarely been described. This report presents a case of hypercalcemia seen in a patient with advanced penile cancer. A chemotherapy regimen of intravenous cisplatin and fluorouracil caused regression of the primary tumor and normalization of the serum calcium. A literature review supported an association between squamous cell carcinoma of the penis and hypercalcemia.
authors.affiliation: Department of Radiation Oncology, London Regional Cancer Centre, Ontario, Canada.
authors.forename: G M
authors.initials: GM
authors.lastname: Videtic
authors.forename: C T
authors.initials: CT
authors.lastname: Ago
authors.forename: E W
authors.initials: EW
authors.lastname: Winquist
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000188:drug therapy*; D002945:Cisplatin / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D006934:Hypercalcemia / Q000150:complications*; D008297:Male; D008875:Middle Aged; D010412:Penile Neoplasms / Q000150:complications* / Q000188:drug therapy*
chemical_list: D002945:Cisplatin; D005472:Fluorouracil