title: Chlamydia trachomatis infection in prelabour amniorrhexis.
abstract: The prevalence of Chlamydia trachomatis in the lower genital tract and amniotic fluid of women with preterm prelabour amniorrhexis was assessed by DNA amplification for C. trachomatis performed in cervical swabs and amniotic fluid obtained by amniocentesis. C. trachomatis was present in the cervix of 20 (23%) of the cases and in six (30%) of those the organism was also present in the amniotic fluid. There was no association with other pathogens in the lower genital tract or amniotic fluid. The presence of C. trachomatis was not associated with a significant decrease in the amniorrhexis to delivery interval or with an increase in perinatal mortality or morbidity.
authors.affiliation: Harris Birthright research Centre for Fetal Medicine, King's College Hospital Medical School, London, UK.
authors.forename: Y
authors.initials: Y
authors.lastname: Vile
authors.forename: S G
authors.initials: SG
authors.lastname: Carroll
authors.forename: P
authors.initials: P
authors.lastname: Watts
authors.forename: M
authors.initials: M
authors.lastname: Ward
authors.forename: K H
authors.initials: KH
authors.lastname: Nicolaides
mesh_terms: D000650:Amnion / Q000382:microbiology*; D002690:Chlamydia Infections / Q000150:complications*; D002692:Chlamydia trachomatis / Q000235:genetics / Q000302:isolation & purification*; D004269:DNA, Bacterial / Q000302:isolation & purification; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000382:microbiology*; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology*
chemical_list: D004269:DNA, Bacterial