title: [Clinical experience for ventricular assist device].
abstract: We began applying of our VAD system clinically in 1982 and have subsequently obtained good results. The first case treated with the VAD returned to normal life. In a total of 70 cases of clinical applications this system there has been instance of apparatus dysfunction. Confirming the reliability and safety promised by the results of biological experiments. Here, we report the results of clinical application of the system in a total of 61 cases between August, 1985 and March, 1989. The following conclusions were reached: 1) Satisfactory weaning and survival rates were obtained i.e. 18 cases out of 61 cases (30%) survived over one month and 13 cases (21%) are currently surviving, even in elderly patients of 60 years of age or older. 2) The weaning rate and survival rates were good after approximately 1 week of support. Detailed evaluation of the recovery of the heart and functions of other major organs has led to the conclusion that the results can be improved further when the weaning period is carefully determined. 3) With regard to surgical factors, good findings were obtained when the artificial heart-lung bypass time was less than 6 hours. The VAD can be used in the early stages without vainly attempting weaning from the artificial heart-lung bypass. 4) There were no mechanical problems with the hardware of the blood pump drive assembly, etc., or noteworthy side effects.
authors.forename: Y
authors.initials: Y
authors.lastname: Sezai
authors.forename: K
authors.initials: K
authors.lastname: Atsumi
authors.forename: I
authors.initials: I
authors.lastname: Fujimasa
authors.forename: K
authors.initials: K
authors.lastname: Imachi
authors.forename: H
authors.initials: H
authors.lastname: Koyanagi
authors.forename: T
authors.initials: T
authors.lastname: Horiuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Orime
mesh_terms: D000368:Aged; D002303:Cardiac Output, Low / Q000628:therapy; D005069:Evaluation Studies as Topic; D005260:Female; D006353:Heart-Assist Devices; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications; D015996:Survival Rate