[Primary cytomegalovirus infection and pregnant women: epidemiological study on 1100 women at Limoges].
During 13 months, 1101 women attending for antenatal care at Limoges University Hospital were prospectively studied to determine the prevalence of Cytomegalovirus (CMV) antibodies: 47.9% of these women were CMV seropositive. Ethnic group was strongly associated with CMV status: 42.6% of metropolitan and 94.5% of immigrant women were seropositive. Seropositivity was associated with increasing parity and older age. The risk of a susceptible woman to acquire CMV infection during pregnancy is 0.7%. Among the 4 seroconversions, 3 children were infected, with developmentally and neurologically normal status in one case, moderate ear damage in an other case and a disseminated infection in the third case requiring a provoked abortion.
Gambarotto
K
K
Laboratoire de Bactériologie-Virologie-Hygiène, CHRU Dupuytren, LIMOGES, France.
Ranger-Rogez
S
S
Aubard
Y
Y
Piver
P
P
Duffetelle
B
B
Delpeyroux
C
C
Roussanne
M C
MC
Nicot
T
T
Denis
F
F
D000328:Adult; D000367:Age Factors; D000368:Aged; D001782:Blood Donors / Q000706:statistics & numerical data; D003587:Cytomegalovirus; D003586:Cytomegalovirus Infections / Q000150:complications / Q000453:epidemiology* / Q000208:ethnology / Q000635:transmission; D005260:Female; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008875:Middle Aged; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology*; D011446:Prospective Studies