[Determination of nucleotide sequences of Russian isolates of delta hepatitis virus].
Genome RNA of hepatitis Delta virus (HDV) was isolated from the blood sera of 4 independently infected patients. The genome fragment of 901-1265 was obtained for each isolate by the RT-PCR. The resultant sequences showed that all isolates belonged to HDV genotype I. Russian isolates were shown to be closely related to an Italian one (98.1-97.5% and 97.1-95.1% identity for the nucleic acid and amino acid levels, respectively); they may represent an extra subtype within genotype I. No appreciable differences between the Russian strains were found, which fact may reflect a possible homogeneity of HDV population in North-Western Russia.
Ryzhova
E V
EV
Reshetnikova
O Iu
OIu
Grudinin
M P
MP
Ivaniushina
V A
VA
Kiselev
O I
OI
D001483:Base Sequence; D018076:DNA, Complementary; D003698:Hepatitis Delta Virus / Q000145:classification / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012367:RNA, Viral; D012426:Russia; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity
D018076:DNA, Complementary; D012367:RNA, Viral