Treatment of HIV-related scabies with emphasis on the efficacy of ivermectin.
Since the mid-1980s, worldwide reports confirm that scabies in individuals infected with the human immunodeficiency virus (HIV) result in a wide range of-clinical manifestations which differ from those seen in immunocompetent patients. There is also general agreement that HIV-related scabies is more difficult to treat. Oral ivermectin has been shown in several countries to be a safe and effective therapy. In otherwise healthy persons, one dose of 200 microg/kg is usually curative. In HIV-related scabies, one treatment may be curative but repeated doses may be required. Crusted scabies in these individual requires a combination of oral ivermectin, total body treatments with 5% permethrin cream, and keratolytic agents to hasten removal of crusts.
Taplin
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Department of Dermatology, University of Miami School of Medicine, FL 33101, USA.
Meinking
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D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy*; D000284:Administration, Oral; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007306:Insecticides / Q000627:therapeutic use*; D007559:Ivermectin / Q000627:therapeutic use*; D008297:Male; D012532:Scabies / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
D007306:Insecticides; D007559:Ivermectin