title: [Tuberculosis in patients with HIV infection].
abstract: Within 1987-1995 the authors observed 16 cases of tuberculosis in HIV-infected patients which accounted for 26.7% of AIDS patients treated by them. 14 cases were diagnosed intravitally, 2 postmortem. Infiltrative, generalized, cavernous, intrathoracic lymph node, intraabdominal lymph node tuberculosis and tuberculous pleurisy were identified in 5, 6, 2, 1, 1 and 1 patients, respectively. 6 patients from the above are still alive and are receiving treatment (5 of them with infiltrative tuberculosis), 10 died. Tuberculosis course and outcomes in HIV-infected subjects depended on the stage of their immunodeficiency. In moderate immunodeficiency (CD4-lymphocyte > 200/mm3) tuberculosis ran, as a rule, as local and infiltrative, sensitive to specific therapy. In severe damage to immune system (CD4 < 100/mm3) tuberculosis acquired a generalized course, sometimes fulminant, resistant to treatment. It is inferred that HIV-infected subjects with immunodeficiency need tuberculosis prophylaxis with isoniazide or rifampicin.
authors.forename: A V
authors.initials: AV
authors.lastname: Kravchenko
authors.forename: O G
authors.initials: OG
authors.lastname: Iurin
authors.forename: L P
authors.initials: LP
authors.lastname: Alekseeva
authors.forename: V A
authors.initials: VA
authors.lastname: Utekhin
authors.forename: T N
authors.initials: TN
authors.lastname: Ermak
authors.forename: L V
authors.initials: LV
authors.lastname: Serebrovskaia
authors.forename: V I
authors.initials: VI
authors.lastname: Shakhgil'dian
authors.forename: I M
authors.initials: IM
authors.lastname: Roslyĭ
authors.forename: Iu G
authors.initials: IuG
authors.lastname: Parkhomenko
authors.forename: V V
authors.initials: VV
authors.lastname: Serova
authors.forename: B M
authors.initials: BM
authors.lastname: Gruzdev
authors.forename: M A
authors.initials: MA
authors.lastname: Burchik
authors.forename: V V
authors.initials: VV
authors.lastname: Pokrovskiĭ
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000097:blood / Q000175:diagnosis*; D000328:Adult; D015703:Antigens, CD / Q000097:blood; D000944:Antigens, Differentiation, B-Lymphocyte / Q000097:blood; D018791:CD4 Lymphocyte Count; D018414:CD8-Positive T-Lymphocytes / Q000166:cytology; D015815:Cell Adhesion Molecules; D005260:Female; D015483:HIV Antibodies / Q000097:blood; D015497:HIV-1; D006487:Hemostasis; D006801:Humans; D007159:Immunologic Tests; D037102:Lectins; D018655:Lymphocyte Count; D008297:Male; D008875:Middle Aged; D051918:Sialic Acid Binding Ig-like Lectin 2; D014388:Tuberculosis, Lymph Node / Q000097:blood / Q000175:diagnosis; D014397:Tuberculosis, Pulmonary / Q000097:blood / Q000175:diagnosis*
chemical_list: D015703:Antigens, CD; D000944:Antigens, Differentiation, B-Lymphocyte; C497867:CD22 protein, human; D015815:Cell Adhesion Molecules; D015483:HIV Antibodies; D037102:Lectins; D051918:Sialic Acid Binding Ig-like Lectin 2