Impact of d-amphetamine on temporal estimation in pigeons tested with a production procedure.
The influence of d-amphetamine on timing in pigeons was examined with a production procedure. Birds were trained with a fixed time schedule in which food reinforcement was contingent on the first response made after a duration signal had appeared for 30 s. Probe tests involved trials in which the duration signal was extended to 90 s and reinforcement was omitted. In Experiment 1, 2.0 mg/kg d-amphetamine shifted peak responding to a duration shorter than that found with saline. In Experiment 2, the dose-response function for this drug effect was examined. A 0.3-mg/kg dose of d-amphetamine had no impact on performance, but a 1.0-mg/kg dose shifted the peak duration significantly relative to saline; a 2.0-mg/kg dose shifted the function even more. These results complement previous findings with rats tested with the peak procedure and pigeons tested with a discrimination procedure.
Kraemer
P J
PJ
Department of Psychology, University of Kentucky, Lexington 40506, USA. pjkrae@pop.uky.edu
Randall
C K
CK
Dose
J M
JM
Brown
R W
RW
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D000697:Central Nervous System Stimulants / Q000494:pharmacology*; D010856:Columbidae; D003913:Dextroamphetamine / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D013998:Time Perception / Q000187:drug effects*
D000697:Central Nervous System Stimulants; D003913:Dextroamphetamine