[Action of biologically active peptides and steroids on nuclear magnetic resonance relaxation of protons of kidney tissue water in vitro].
The effect of biologically active peptides (adrenocorticotropin, parathyroid hormone, calcitonin, prolactin) and steroids (aldosterone, progesterone, testosterone) hormones on NMR-relaxation proton of tissue water of kidney have been investigated in vitro. Results of this study suggest that peptide hormones caused dehydration of tissues via sodium regulation. Steroids, quite on the contrary, caused the hydration of kidney tissue independent of the movement of osmotic active electrolyte.
Komarevtseva
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IA
Orlova
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EA
D000324:Adrenocorticotropic Hormone / Q000494:pharmacology; D000450:Aldosterone / Q000494:pharmacology; D000818:Animals; D001834:Body Water / Q000187:drug effects*; D002116:Calcitonin / Q000494:pharmacology; D066298:In Vitro Techniques; D007668:Kidney / Q000187:drug effects*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D009997:Osmotic Pressure / Q000187:drug effects; D010281:Parathyroid Hormone / Q000494:pharmacology; D010455:Peptides / Q000494:pharmacology*; D011374:Progesterone / Q000494:pharmacology; D011388:Prolactin / Q000494:pharmacology; D011522:Protons; D051381:Rats; D017208:Rats, Wistar; D013256:Steroids / Q000494:pharmacology*
D010281:Parathyroid Hormone; D010455:Peptides; D011522:Protons; D013256:Steroids; D000450:Aldosterone; D011374:Progesterone; D000324:Adrenocorticotropic Hormone; D011388:Prolactin; D002116:Calcitonin