Inactivation of prostaglandin endoperoxide synthase (PGHS) by N-(substituted)maleimides.
Kalgutkar
A S
AS
A. B. Hancock, Jr., Memorial Laboratory for Cancer Research, Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-0146, USA.
Crews
B C
BC
Marnett
L J
LJ
D002210:Caprylates / Q000494:pharmacology; D016861:Cyclooxygenase Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D008301:Maleimides / Q000737:chemistry / Q000494:pharmacology*; D010544:Peroxidases / Q000037:antagonists & inhibitors; D011451:Prostaglandin-Endoperoxide Synthases / Q000187:drug effects*; D013379:Substrate Specificity; D014357:Trypsin / Q000494:pharmacology
D002210:Caprylates; D016861:Cyclooxygenase Inhibitors; D008301:Maleimides; C109338:N-(carboxyheptyl)maleimide; D010544:Peroxidases; D011451:Prostaglandin-Endoperoxide Synthases; D014357:Trypsin