[Effect of imuran on the activity of metalloenzymes and parameters of metal metabolism in the body].
Retention of iron, copper and cobalt in the guinea pig organism as affected by imuran increases while that of zinc sharply decreases. These bioelements are considerably redistributed in the blood, skin, liver, muscles, bones, spleen; activity of metalloenzymes conjugated with them (lactate dehydrogenase, carboanhydrase, alkaline phosphatase, ceruloplasmin) in the blood changes.
Babenko
H O
HO
Zaviĭs'kyĭ
Iu M
IuM
D000469:Alkaline Phosphatase / Q000097:blood / Q000187:drug effects; D000818:Animals; D001379:Azathioprine / Q000494:pharmacology*; D002256:Carbonic Anhydrases / Q000097:blood / Q000187:drug effects; D002374:Catalase / Q000097:blood / Q000187:drug effects; D002570:Ceruloplasmin / Q000187:drug effects; D006168:Guinea Pigs; D007770:L-Lactate Dehydrogenase / Q000097:blood / Q000187:drug effects; D008297:Male; D008667:Metalloproteins / Q000097:blood / Q000187:drug effects*
D008667:Metalloproteins; D007770:L-Lactate Dehydrogenase; D002374:Catalase; D002570:Ceruloplasmin; D000469:Alkaline Phosphatase; D002256:Carbonic Anhydrases; D001379:Azathioprine