title: Nesting and shredding behavior as an indicator of hippocampal ischemic damage.
abstract: Mongolian gerbils were subjected to bilateral carotid artery occlusion, exposed to nesting material and examined daily. Five minutes of ischemia significantly reduced nesting behavior for 3 days; while 10 min attenuated nesting 6 days. Semi-novel re-exposure to nesting material also resulted in deficits. These disruptions in nesting behavior directly correlate to the amount of ischemic morphological damage and thus serve as a behavioral indicator of tissue damage.
authors.affiliation: Department of Neurology, SUNY at Stony Brook, NY 11794-8121, USA. fantona@neuro.som.sunysb.edu
authors.forename: F J
authors.initials: FJ
authors.lastname: Antonawich
authors.forename: C S
authors.initials: CS
authors.lastname: Melton
authors.forename: P
authors.initials: P
authors.lastname: Wu
authors.forename: J N
authors.initials: JN
authors.lastname: Davis
mesh_terms: D000818:Animals; D002339:Carotid Arteries / Q000502:physiology; D005849:Gerbillinae; D006624:Hippocampus / Q000098:blood supply*; D002546:Ischemic Attack, Transient / Q000523:psychology*; D008297:Male; D009425:Nesting Behavior / Q000502:physiology*; D013997:Time Factors