title: Laser profiling of bovine pericardial heart valves.
abstract: Laser profiling techniques have been used to examine the 2-dimensional and 3-dimensional patterns of leaflet motion in functioning bovine pericardial heart valves (1 normal valve and 1 fatigued/calcified). In the normal valve the general patterns of opening and closing were similar for all leaflets; however, localised variations such as areas of high curvature, retarded motion and high speed motion were identified. In the fatigued/calcified valve significant differences from the normal leaflet motion were observed e.g. increased crimping, gross leaflet lag and irregular deformation. The laser profiling technique was able to reveal changes in the functional dynamics of pericardial valve leaflets not otherwise detectable by conventional hydrodynamic measurements of valve performance.
authors.affiliation: University Department of Cardiac Surgery, Glasgow Royal Infirmary University NHS Trust, UK.
authors.forename: A W
authors.initials: AW
authors.lastname: Donn
authors.forename: G M
authors.initials: GM
authors.lastname: Bernacca
authors.forename: T G
authors.initials: TG
authors.lastname: Mackay
authors.forename: M J
authors.initials: MJ
authors.lastname: Gulbransen
authors.forename: D J
authors.initials: DJ
authors.lastname: Wheatley
mesh_terms: D000818:Animals; D002114:Calcinosis; D002417:Cattle; D006349:Heart Valve Diseases / Q000175:diagnosis*; D007834:Lasers; D008953:Models, Anatomic; D010496:Pericardium / Q000502:physiology