title: Bovine attaching and effacing Escherichia coli possess a pathogenesis island related to the LEE of the human enteropathogenic Escherichia coli strain E2348/69.
abstract: Attaching and effacing Escherichia coli (AEEC) has been described as a cause of diarrhea in calves. The molecular pathogenesis of AEEC was mainly studied in human enteropathogenic E. coli strain E2348/69 in which the virulence correlated with the presence of a 35.4 kb pathogenesis island called LEE. We showed that several strains isolated from calves with diarrhea were able to produce attaching and effacing lesions in a rabbit ileal loop model and that they possess a pathogenesis island related to the LEE. Moreover, we showed that the LEE from bovine strains was inserted mainly at a different position in the chromosome compared to the human enteropathogenic E. coli strain E2348/69.
authors.affiliation: University of Liège, Faculty of Veterinary Medicine, Laboratory of Bacteriology, Belgium.
authors.forename: F
authors.initials: F
authors.lastname: Goffaux
authors.forename: J
authors.initials: J
authors.lastname: Mainil
authors.forename: V
authors.initials: V
authors.lastname: Pirson
authors.forename: G
authors.initials: G
authors.lastname: Charlier
authors.forename: P
authors.initials: P
authors.lastname: Pohl
authors.forename: E
authors.initials: E
authors.lastname: Jacquemin
authors.forename: B
authors.initials: B
authors.lastname: China
mesh_terms: D000818:Animals; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology*; D002874:Chromosome Mapping; D003967:Diarrhea / Q000382:microbiology* / Q000662:veterinary; D004926:Escherichia coli / Q000472:pathogenicity*; D006801:Humans; D016133:Polymerase Chain Reaction; D011817:Rabbits