title: [Chlamydia infection and female low fertility in Morocco].
abstract: Chlamydia trachomatis infection is recognised as the most common asymptomatic sexually transmitted disease, and this may lead to severe complication including infertility. The purpose of this study was to evaluate the part that this pathology takes in the female hypofertility, using serologic, cell culture, and histopathologic tests. Some of the women had undergone biopsies during coelioscopic exam, the others during salpingectomy. Cervical specimens were carried from other women. They had as clinical signs: primary or secondary infertility, ectopic pregnancy, syndrome of synechie, hydrosalpinx, or pelvic pains. 128 of these women had undergone serologic exam, 57 a cell culture, and 47 an histopathologic test. The results showed that 26% had anti Chlamydia trachomatis antibodies and 46% from them with tubal problems confirmed, had anti Chlamydia trachomatis antibodies as well, only 7% had cell culture positive from cervix specimens, none from the biopsies, and 73% of them had inflammatory responses. All women with inflammatory responses had a serologic and/or cell culture positive tests. Our results allow us to conclude that this infection takes a good part in female hypofertility, there is a correlation between a previous Chlamydia trachomatis infection and a tubal histopathology. In front of the difficulties of isolation by cell culture the detection of the microorganism by molecular biology assays may resolve a lot of problems.
authors.affiliation: Laboratoire des Chlamydiae, Institut Pasteur du Maroc, Casablanca, Maroc.
authors.forename: F
authors.initials: F
authors.lastname: Radouani
authors.forename: B
authors.initials: B
authors.lastname: Takourt
authors.forename: H
authors.initials: H
authors.lastname: Benomar
authors.forename: M
authors.initials: M
authors.lastname: Guerbaoui
authors.forename: M
authors.initials: M
authors.lastname: Bekkay
authors.forename: Y
authors.initials: Y
authors.lastname: Boutaleb
authors.forename: R
authors.initials: R
authors.lastname: Guinet
authors.forename: S
authors.initials: S
authors.lastname: Ibrahimy
authors.forename: A
authors.initials: A
authors.lastname: Benslimane
mesh_terms: D000328:Adult; D001706:Biopsy; D002478:Cells, Cultured; D002584:Cervix Uteri / Q000166:cytology / Q000382:microbiology / Q000473:pathology; D002690:Chlamydia Infections / Q000150:complications*; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology*; D009018:Morocco; D011247:Pregnancy