Clomipramine-induced tourettism in obsessive-compulsive disorder: clinical and theoretical implications.
We report a case in which vocal and motor tics (Tourettism) developed after the administration of clomipramine hydrochloride in a young patient with obsessive compulsive disorder and schizoid personality disorder. Several hypotheses for this occurrence are proposed based on the suggested pathogenesis of Tourette syndrome.
Moshe
K
K
Psychiatric Division, Sheba Medical Center, Tel Hashomer, Israel.
Iulian
I
I
Seth
K
K
Eli
L
L
Joseph
Z
Z
D000328:Adult; D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects* / Q000627:therapeutic use*; D002997:Clomipramine / Q000009:adverse effects* / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000188:drug therapy*; D005879:Tourette Syndrome / Q000139:chemically induced*
D000929:Antidepressive Agents, Tricyclic; D002997:Clomipramine