title: Endocervical infection in a pregnant woman caused by Neisseria meningitidis: evidence of associated oropharyngeal colonization of the male partner.
abstract: A case of premature birth associated with an endocervical infection caused by Neisseria meningitidis is reported. Treatment of the mother with amoxycillin eradicated the bacteria from the endocervix and avoided newborn colonization or infection. Epidemiological investigation identified meningococcal oropharyngeal colonization of the male partner. The two strains were of the same antigenic formula B:4:P1.14 and exhibited identical rDNA restriction fragment patterns and outer membrane protein profiles. This phenotypic and genomic identity of strains is the first clear evidence for cross-colonization between sexual partners.
authors.affiliation: Département de Microbiologie Médicale et Moléculaire, EP CNRS 117, CHU Bretonneau, Tours, France.
authors.forename: P
authors.initials: P
authors.lastname: Harriau
authors.forename: C
authors.initials: C
authors.lastname: Ramanantsoa
authors.forename: F
authors.initials: F
authors.lastname: Pierre
authors.forename: J Y
authors.initials: JY
authors.lastname: Riou
authors.forename: R
authors.initials: R
authors.lastname: Quentin
mesh_terms: D000328:Adult; D000658:Amoxicillin / Q000008:administration & dosage / Q000627:therapeutic use; D015373:Bacterial Typing Techniques; D002584:Cervix Uteri / Q000382:microbiology* / Q000473:pathology; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008565:Membrane Proteins / Q000032:analysis; D008589:Meningococcal Infections / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D009345:Neisseria meningitidis / Q000145:classification / Q000254:growth & development / Q000302:isolation & purification; D007752:Obstetric Labor, Premature / Q000382:microbiology*; D009960:Oropharynx / Q000382:microbiology*; D010406:Penicillins / Q000008:administration & dosage / Q000627:therapeutic use; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000382:microbiology*; D011256:Pregnancy Outcome; D002577:Uterine Cervical Diseases / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D014626:Vaginal Smears
chemical_list: D008565:Membrane Proteins; D010406:Penicillins; D000658:Amoxicillin