The soil fungus Chaetomium in the human paranasal sinuses.
Chaetomium is a soil fungus of which more than 180 species are now known. Most species cause degradation of cellulose-rich substrates, such as components in soil, straw or wood. Growth of Chaetomium globosum is often stimulated in the presence of Aspergillus fumigatus, which excretes such compounds as sugar phosphates and phospho-glyceric acid. A 73-year-old woman, with long-standing pain and secretion from her left maxillary sinus, was admitted to hospital where an infundibulectomy was performed. Histological examination showed necrotic material with hyphae of A. fumigatus and perithecia of Chaetomium sp. The latter fungus is rarely pathogenic to man.
Aru
A
A
Department of Pathology, Frederiksborg County Hospital, Hillerød, Denmark.
Munk-Nielsen
L
L
Federspiel
B H
BH
D000368:Aged; D000935:Antifungal Agents / Q000627:therapeutic use; D001232:Aspergillus fumigatus / Q000302:isolation & purification; D002597:Chaetomium / Q000302:isolation & purification*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D015523:Maxillary Sinusitis / Q000382:microbiology* / Q000628:therapy; D009181:Mycoses / Q000628:therapy; D010406:Penicillins / Q000627:therapeutic use
D000935:Antifungal Agents; D010406:Penicillins