title: Update on antifungal resistance.
abstract: Overuse of antifungal agents has resulted in the selection of naturally resistant Candida species, as well as expression of resistance from previously susceptible species resulting from genetic mutations and/or selection of resistant subpopulations. Strategies for the appropriate use of antifungal agents need to be developed to prevent further development of resistance.
authors.affiliation: University of Iowa College of Pharmacy, Iowa City 52242, USA. michael-klepser@uiowa.edu
authors.forename: M E
authors.initials: ME
authors.lastname: Klepser
authors.forename: E J
authors.initials: EJ
authors.lastname: Ernst
authors.forename: M A
authors.initials: MA
authors.lastname: Pfaller
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D002175:Candida / Q000235:genetics / Q000472:pathogenicity; D002177:Candidiasis / Q000188:drug therapy*; D004352:Drug Resistance, Microbial; D004358:Drug Therapy / Q000379:methods; D005658:Fungi / Q000235:genetics / Q000472:pathogenicity; D006801:Humans; D009154:Mutation; D009181:Mycoses / Q000188:drug therapy*
chemical_list: D000935:Antifungal Agents