title: Pediatric idiopathic anaphylaxis: experience with 22 patients.
abstract: Idiopathic anaphylaxis in the pediatric population is being increasingly recognized, with symptoms (and therefore classifications) the same as those described in adults. We present a series of 22 patients with special attention to considerations relatively unique to the pediatric population. Prednisone, hydroxyzine, and albuterol were used to control symptoms and induce remission. No deaths occurred during treatment. One adolescent who presented with corticosteroid-dependent idiopathic anaphylaxis was diagnosed with undifferentiated somatoform-idiopathic anaphylaxis. Local physician reluctance to participate in management complicated care for some patients.
authors.affiliation: Department of Medicine and the Ernest S. Bazley Asthma and Allergic Diseases Center of Northwestern Memorial Hospital and Northwestern University Medical School, Chicago, IL 60611, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Ditto
authors.forename: J
authors.initials: J
authors.lastname: Krasnick
authors.forename: P A
authors.initials: PA
authors.lastname: Greenberger
authors.forename: K J
authors.initials: KJ
authors.lastname: Kelly
authors.forename: K
authors.initials: K
authors.lastname: McGrath
authors.forename: R
authors.initials: R
authors.lastname: Patterson
mesh_terms: D000293:Adolescent; D000318:Adrenergic beta-Agonists / Q000627:therapeutic use; D000328:Adult; D000420:Albuterol / Q000627:therapeutic use; D000707:Anaphylaxis / Q000175:diagnosis* / Q000188:drug therapy / Q000453:epidemiology; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002648:Child; D003695:Delivery of Health Care; D003937:Diagnosis, Differential; D005260:Female; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D006919:Hydroxyzine / Q000627:therapeutic use; D008297:Male; D010818:Practice Patterns, Physicians'; D011241:Prednisone / Q000627:therapeutic use
chemical_list: D000318:Adrenergic beta-Agonists; D000893:Anti-Inflammatory Agents; D006634:Histamine H1 Antagonists; D006919:Hydroxyzine; D000420:Albuterol; D011241:Prednisone