Experimental evaluation of a new device for percutaneous transrenal ureteral occlusion.
OBJECTIVE
To develop a device for percutaneous transrenal ureteral occlusion.


METHODS
The device was a double-body Gianturco-Rösch biliary stent constrained at the junction of the two stents to create an hourglass shape. One stent was coated with silicone. One device was percutaneously placed in each of nine pigs through a 9-F Teflon sheath. Urographic and hematologic follow-up was performed for up to 12 weeks.


RESULTS
Seven pigs showed immediate, complete ureteral occlusion, and two pigs exhibited persistent incomplete high-grade obstruction. All animals exhibited varying degrees of hydronephrosis and hydroureter. No device migration was noted. Minor complications were encountered during device placement in three pigs. Mucosal folds and villus-like projections that arose from the lamina propria protruded into the lumen of the ureter at the cranial end of the covered stent and around the wire of the caudal stent. Varying degrees of mural inflammation and edema were noted.


CONCLUSIONS
Transrenal ureteral occlusion with the described device appears to be a viable method for treating urinary fistulas.
Marr
B
B
Department of Diagnostic Radiology, The University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.
Wright
K C
KC
Carrasco
C H
CH
Brewer
L
L
D000818:Animals; D007668:Kidney / Q000473:pathology; D015607:Stents; D013552:Swine; D013556:Swine, Miniature; D014513:Ureter / Q000473:pathology; D014548:Urinary Fistula / Q000628:therapy