title: Human colonic microvascular endothelial cells is a model of inflammatory bowel disease.
abstract: BACKGROUND
  The pathophysiology of inflammatory bowel disease remains elusive primarily because of the limitations of the models available for study in the basic science laboratories. We propose a new model for the study of inflammatory bowel disease.
  
  
  METHODS
  Research and review articles published in the English literature.
  
  
  CONCLUSIONS
  The human colonic microvascular endothelial cell in culture is a legitimate model for the study of the human colon in the normal and diseased states.
authors.affiliation: Department of Surgery, University of California, San Francisco 94143-0144, USA.
authors.forename: M L
authors.initials: ML
authors.lastname: Welton
mesh_terms: D001920:Bradykinin / Q000502:physiology; D003106:Colon / Q000098:blood supply*; D016228:Endothelial Growth Factors / Q000502:physiology; D004730:Endothelium, Vascular / Q000166:cytology* / Q000502:physiology; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000503:physiopathology*; D008833:Microcirculation / Q000166:cytology / Q000502:physiology; D008954:Models, Biological; D013373:Substance P / Q000502:physiology
chemical_list: D016228:Endothelial Growth Factors; D013373:Substance P; D001920:Bradykinin