Ro 45-2081, a TNF receptor fusion protein, prevents inflammatory responses in the airways.
Renzetti
L M
LM
Hoffmann-LaRoche Inc., Nutley, NJ 07110, USA. Louis_M.Renzetti@Roche.com
Gater
P R
PR
D000818:Animals; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology; D004804:Eosinophils / Q000473:pathology; D006168:Guinea Pigs; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000627:therapeutic use*; D007142:Immunoglobulin gamma-Chains; D007249:Inflammation / Q000276:immunology / Q000473:pathology / Q000517:prevention & control; D008168:Lung / Q000473:pathology; D008171:Lung Diseases / Q000276:immunology / Q000473:pathology / Q000517:prevention & control*; D008297:Male; D009504:Neutrophils / Q000473:pathology; D010047:Ovalbumin / Q000276:immunology; D011654:Pulmonary Edema / Q000276:immunology / Q000517:prevention & control; D051381:Rats; D018124:Receptors, Tumor Necrosis Factor / Q000627:therapeutic use*; D011993:Recombinant Fusion Proteins / Q000627:therapeutic use; D012130:Respiratory Hypersensitivity / Q000276:immunology / Q000473:pathology / Q000517:prevention & control*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
D007143:Immunoglobulin Heavy Chains; D007142:Immunoglobulin gamma-Chains; D018124:Receptors, Tumor Necrosis Factor; D011993:Recombinant Fusion Proteins; D014409:Tumor Necrosis Factor-alpha; C099374:Ro 45-2081; D010047:Ovalbumin