Manauealides, some of the causative agents of a red alga Gracilaria coronopifolia poisoning in Hawaii.
Manauealides A-C (1-3), compounds related to debromoaplysiatoxin (5), were isolated and characterized from a red alga Gracilaria coronopifolia. Compounds 1 and 2 are presumed to be the causative toxins of G. coronopifolia food poisoning in Hawaii. Manauealide A (1) and C (3) are new macrolides, whereas manauealide B (2) is a known semisynthetic product of 5.
Nagai
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Suntory Institute for Bioorganic Research, Osaka, Japan. LEE05540@niftyserve.or.jp
Yasumoto
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T
Hokama
Y
Y
D002240:Carbohydrate Sequence; D002851:Chromatography, High Pressure Liquid; D005517:Foodborne Diseases / Q000503:physiopathology*; D006254:Hawaii; D008235:Lyngbya Toxins / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity; D018942:Macrolides / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity; D009682:Magnetic Resonance Spectroscopy; D008387:Marine Toxins / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity; D008969:Molecular Sequence Data; D000461:Rhodophyta / Q000737:chemistry*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013056:Spectrophotometry, Ultraviolet
D008235:Lyngbya Toxins; D018942:Macrolides; D008387:Marine Toxins; C108754:manauealide A; C108755:manauealide B; C108756:manauealide C