title: Synthesis and antimicrobial activities of some new 2-substituted benzoxazole/benzothiazole derivatives.
abstract: In the search for new antimicrobial compounds, several new sulfur bearing heterobicyclic moieties (4-11) have been synthesized by acylation and alkylation of acetamide, thioacetamide and semicarbazide derivatives. The structure of the products was deduced from elemental analyses as well as spectral data (IR, 1H NMR and MS). Significant antimicrobial activities were obtained for all new compounds especially against Fusarium oxysporum.
authors.affiliation: Department of Chemistry, Faculty of Education, Ain-Shams University, Roxy, Cairo.
authors.forename: H M
authors.initials: HM
authors.lastname: el-Shaaer
authors.forename: S A
authors.initials: SA
authors.lastname: Abdel-Aziz
authors.forename: H A
authors.initials: HA
authors.lastname: Allimony
authors.forename: U F
authors.initials: UF
authors.lastname: Ali
authors.forename: R M
authors.initials: RM
authors.lastname: Abdel-Rahman
mesh_terms: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001232:Aspergillus fumigatus / Q000187:drug effects; D001419:Bacteria / Q000187:drug effects; D001583:Benzoxazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D005670:Fusarium / Q000187:drug effects; D006375:Helminthosporium / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D013055:Spectrophotometry, Infrared; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D001583:Benzoxazoles; D013844:Thiazoles