The calyxolanes: new 1,3-diphenylbutanoid metabolites isolated from the Caribbean marine sponge Calyx podatypa.
Calyxolanes A (1) and B (2) are rare 1,3-diphenylbutanoid compounds isolated from the marine sponge Calyx podatypa collected in Puerto Rico. Their structures, including relative stereochemistry, have been determined by spectroscopic methods. The unique 2,4-diphenyloxolane function in 1 and 2 was established by 2D 1H-1H and 1H-13C NMR correlation experiments and confirmed by mass spectral analysis. A suggestion is made as to their biogenetic origin.
Rodríguez
A D
AD
Department of Chemistry, University of Puerto Rico, Río Piedras, Puerto Rico 00931-3346, USA.
Cóbar
O M
OM
Padilla
O L
OL
D000818:Animals; D005663:Furans / Q000302:isolation & purification* / Q000494:pharmacology; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D011161:Porifera / Q000737:chemistry*; D013237:Stereoisomerism
D005663:Furans; C108749:calyxolane A; C108750:calyxolane B