Organ-preserving management of rhabdomyosarcoma of the prostate and bladder in children.
Between November 1978 and July 1991, ten children between one and eight years of age with Group III pelvic rhabdomyosarcoma (IRS classification) and considered inoperable at diagnosis were treated primarily with intensive poly-chemotherapy. Complementary radiotherapy and conservative surgery were added as needed. Eight of the ten survive free of disease with functioning bladders for periods ranging from 5.7-18.4 years.
Silván
A M
AM
Department of Oncology, Hospital Uniersitario Infantil Virgen del Rocio de Sevilla, Spain.
Gordillo
M J
MJ
Lopez
A M
AM
Cuevas
G P
GP
Gutiérrez
J A
JA
Iriondo
J M
JM
Cantón
J A
JA
Caro
A M
AM
Quesada
M L
ML
Arceaga
M A
MA
Vallés
M C
MC
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000628:therapy*; D011879:Radiotherapy Dosage; D012208:Rhabdomyosarcoma / Q000175:diagnosis / Q000628:therapy*; D016019:Survival Analysis; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000628:therapy*