DBT: a partial D phenotype associated with the low-incidence antigen Rh32.
Eight probands are described with a D phenotype in which a partial D antigen is associated with Rh32 antigen; three of these probands were investigated because of the anti-D in their serum. The partial D lacks epD1-epD5 and epD9 and some epD6/7 and only expresses epD8 and other parts of epD6/7. The strength of the partial D antigen varies between unrelated DBT individuals. The Rh32 antigen of the DBT cells is weaker than that of D(C)(e) cells. Tests on DBT, DFR and R0Har cells with anti-epD6/7 split these monoclonal anti-D into eight patterns of reaction. A new pattern of reactions was observed, presaging a new epitope, but this was not numbered.
Wallace
M
M
Medical Research Council Blood Group Unit, London, UK.
Lomas-Francis
C
C
Beckers
E
E
Bruce
M
M
Campbell
G
G
Chatfield
S
S
Nagao
N
N
Okubo
Y
Y
Opalka
A
A
Overbeeke
M
M
Scott
M
M
Voak
D
D
D000911:Antibodies, Monoclonal; D005260:Female; D006801:Humans; D015994:Incidence; D010375:Pedigree; D010641:Phenotype; D012204:Rh-Hr Blood-Group System / Q000235:genetics*
D000911:Antibodies, Monoclonal; D012204:Rh-Hr Blood-Group System; C026410:Rho(D) antigen