title: Daminozide--lack of the genotoxic activity in the short-term bacterial tests.
abstract: Daminozide [ALAR] a plant growth regulator has been widely used on apples since the late 1960s. It has been identified as a possible carcinogen. Restrictions were ordered to reduce both application rates and allowable daminozide residue levels. Since conclusive scientific data necessary to characterize the risk of daminozide were not available, additional information on mutagenic activity of this compound was needed.
authors.affiliation: Department of Biochemistry, Medical School, Warsaw, Poland.
authors.forename: I
authors.initials: I
authors.lastname: Rahden-Staroń
authors.forename: M
authors.initials: M
authors.lastname: Szumiło
authors.forename: P
authors.initials: P
authors.lastname: Ziemkiewicz
authors.forename: T
authors.initials: T
authors.lastname: Szymczyk-Wasiluk
mesh_terms: D000469:Alkaline Phosphatase / Q000187:drug effects; D000818:Animals; D004269:DNA, Bacterial / Q000187:drug effects*; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology; D008099:Liver / Q000187:drug effects; D008297:Male; D009152:Mutagenicity Tests; D010937:Plant Growth Regulators / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000235:genetics; D013045:Species Specificity; D013386:Succinates / Q000633:toxicity*; D001616:beta-Galactosidase / Q000187:drug effects
chemical_list: D004269:DNA, Bacterial; D010937:Plant Growth Regulators; D013386:Succinates; D000469:Alkaline Phosphatase; D001616:beta-Galactosidase; C014499:daminozide