Autoimmune reactivity in inflammatory bowel disease.
Inflammatory bowel disease remains a poorly understood chronic inflammatory condition of the bowel. No etiologic agents, or agreed upon pathogenesis is currently known. Recent findings that perinuclear antineutrophil cytoplasmic antibodies (P-ANCA) are present in the vast majority of patients with this disease have proven to be of use in epidemiologic studies. Its clinical use is currently being explored by several investigators.
Keren
D F
DF
Warde Medical Laboratory, Department of Pathology, St. Joseph Mercy Hospital, Ann Arbor, Michigan, USA.
Goeken
J A
JA
D019268:Antibodies, Antineutrophil Cytoplasmic / Q000032:analysis*; D003093:Colitis, Ulcerative / Q000276:immunology* / Q000473:pathology; D003424:Crohn Disease / Q000276:immunology* / Q000473:pathology; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D009504:Neutrophils / Q000276:immunology
D019268:Antibodies, Antineutrophil Cytoplasmic