title: Why "underpowered" trials are not necessarily unethical.
authors.affiliation: Department of Public Health and Epidemiology, University of Birmingham Medical School, UK.
authors.forename: S J
authors.initials: SJ
authors.lastname: Edwards
authors.forename: R J
authors.initials: RJ
authors.lastname: Lilford
authors.forename: D
authors.initials: D
authors.lastname: Braunholtz
authors.forename: J
authors.initials: J
authors.lastname: Jackson
mesh_terms: D002986:Clinical Trials as Topic / Q000706:statistics & numerical data; D026689:Ethical Analysis; D028744:Ethics Committees, Research; D004992:Ethics, Medical; D005188:False Negative Reactions; D005189:False Positive Reactions; D006801:Humans; D035842:Research Subjects; D018401:Sample Size; D036302:Therapeutic Human Experimentation