title: EGF-receptor tyrosine kinase and 12-lipoxygenase activity regulate expression of 12-lipoxygenase in human tumor cells.
authors.affiliation: Division of Tumor Biochemistry, Deutsches Krebsforschungszentrum, Heidelberg, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Hagmann
authors.forename: S
authors.initials: S
authors.lastname: Borgers
mesh_terms: D001092:Arachidonate 12-Lipoxygenase / Q000096:biosynthesis* / Q000235:genetics; D001710:Biotin / Q000031:analogs & derivatives / Q000494:pharmacology; D002294:Carcinoma, Squamous Cell / Q000473:pathology; D004790:Enzyme Induction / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology; D004815:Epidermal Growth Factor / Q000494:pharmacology*; D066246:ErbB Receptors / Q000037:antagonists & inhibitors / Q000502:physiology*; D015972:Gene Expression Regulation, Neoplastic / Q000187:drug effects*; D006801:Humans; D009363:Neoplasm Proteins / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D010590:Phalloidine / Q000031:analogs & derivatives / Q000494:pharmacology; D010797:Phthalimides / Q000494:pharmacology; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000096:biosynthesis / Q000235:genetics; D015398:Signal Transduction / Q000187:drug effects; D014407:Tumor Cells, Cultured
chemical_list: D004791:Enzyme Inhibitors; D009363:Neoplasm Proteins; D010797:Phthalimides; D012333:RNA, Messenger; C060047:4-(3-(biotinylaminohexamethylenaminocarbonyl)propanoylaminomethyl)-2-methyl-1,3-dithiolane-2-yl-(Ala(7))phalloidin; D010590:Phalloidine; D004815:Epidermal Growth Factor; D001710:Biotin; D001092:Arachidonate 12-Lipoxygenase; D066246:ErbB Receptors; C098874:4,5-dianilinophthalimide