Desmoplastic fibroma of the temporal bone.
BACKGROUND
Desmoplastic fibroma is a benign, locally aggressive, intraosseous neoplasm with a propensity for local recurrence. Desmoplastic fibroma most commonly originates within the mandible (70% of cases), and long bones with rare lesions reported in the maxillary, frontal, and parietal bones. We report two patients with desmoplastic fibroma arising within the temporal bone.


METHODS
Case report and literature review.


METHODS
Two patients with desmoplastic fibroma with intracranial and extra cranial growth patterns are presented. Both were young females with aural fullness and decreased hearing.


METHODS
Diagnostic and therapeutic.


RESULTS
Both tumors were surgically extirpated and the patients have remained disease free for 18-48 months. Neither tumor expressed estrogen or progesterone receptors.


CONCLUSIONS
Desmoplastic fibroma is a highly invasive local destructive lesion which is best treated by nondestructive surgical intervention. Immunohistochemical analysis may demonstrate hormonal receptors, in which case Tamoxifen may reduce recurrence.
Pensak
M L
ML
Department of Otolaryngology, University of Cincinnati College of Medicine, OH 45267-0528, USA.
Nestok
B R
BR
Van Loveren
H
H
Shumrick
K A
KA
D000328:Adult; D005260:Female; D018220:Fibroma, Desmoplastic / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D012888:Skull Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D013701:Temporal Bone / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed