title: Endophthalmitis after astigmatic myopic laser in situ keratomileusis.
abstract: A 36-year-old woman had uneventful astigmatic myopic laser in situ keratomileusis (LASIK) to correct -12.00 -1.50 x 70. Three days later, she developed a corneal abscess, hypopyon, and an intense vitreous cellular reaction-endophthalmitis. The patient was immediately given intravenous ciprofloxacin and topical vancomycin and ceftazidime. The infecting organism was Streptococcus pneumoniae. One day after therapy was instituted, the hypopyon resolved. Seven months later, best corrected visual acuity was 20/25 and refractive error, -4.00 diopters. A stromal scar (grade 2 haze) was causing a slight reduction in acuity. Endophthalmitis after LASIK, if treated promptly, need not lead to a permanent reduction in visual acuity.
authors.affiliation: Department of Ophthalmology, Mater Private Hospital, Dublin, Ireland.
authors.forename: M G
authors.initials: MG
authors.lastname: Mulhern
authors.forename: P I
authors.initials: PI
authors.lastname: Condon
authors.forename: M
authors.initials: M
authors.lastname: O'Keefe
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001251:Astigmatism / Q000601:surgery*; D002442:Ceftazidime / Q000627:therapeutic use; D002511:Cephalosporins / Q000627:therapeutic use; D003228:Conjunctiva / Q000382:microbiology; D003315:Cornea / Q000187:drug effects / Q000382:microbiology / Q000601:surgery*; D016039:Corneal Transplantation / Q000009:adverse effects*; D009877:Endophthalmitis / Q000188:drug therapy / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006801:Humans; D053685:Laser Therapy; D009216:Myopia / Q000601:surgery*; D015242:Ofloxacin / Q000627:therapeutic use; D011008:Pneumococcal Infections / Q000188:drug therapy / Q000209:etiology*; D013296:Streptococcus pneumoniae / Q000302:isolation & purification; D014640:Vancomycin / Q000627:therapeutic use; D014792:Visual Acuity
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D002511:Cephalosporins; D014640:Vancomycin; D002442:Ceftazidime; D015242:Ofloxacin