title: Rheumatoid nodules: MR/pathological correlation.
abstract: OBJECTIVE
  To demonstrate the signal characteristics of subcutaneous rheumatoid nodules in correlation to their histopathologic features.
  
  
  METHODS
  The magnetic resonance imaging (MRI) features of biopsy proven subcutaneous rheumatoid nodules are described in five patients with rheumatoid arthritis established by classic criteria.
  
  
  RESULTS
  Two morphologic appearances of rheumatoid nodules were observed on MRI: one predominantly cystic, with enhancing peripheral component; and a second type which is predominantly solid, with uniform enhancement following gadolinium injection.
  
  
  CONCLUSIONS
  Subcutaneous rheumatoid nodules can appear by MR as solid, cystic, or a combination of both components. This closely correlates with their histopathologic evolution.
authors.affiliation: Department of Radiology, Alexandria University, Egypt.
authors.forename: K I
authors.initials: KI
authors.lastname: el-Noueam
authors.forename: V
authors.initials: V
authors.lastname: Giuliano
authors.forename: M E
authors.initials: ME
authors.lastname: Schweitzer
authors.forename: B J
authors.initials: BJ
authors.lastname: O'Hara
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000175:diagnosis; D001706:Biopsy; D002111:Calcaneus / Q000473:pathology; D003287:Contrast Media; D003560:Cysts / Q000473:pathology; D005260:Female; D005347:Fibroblasts / Q000473:pathology; D005534:Foot Diseases / Q000175:diagnosis* / Q000473:pathology; D005682:Gadolinium; D019786:Gadolinium DTPA; D015726:Giant Cells / Q000473:pathology; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D007089:Image Enhancement; D008264:Macrophages / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009942:Organometallic Compounds; D004369:Pentetic Acid / Q000031:analogs & derivatives; D012218:Rheumatoid Nodule / Q000175:diagnosis* / Q000473:pathology; D012867:Skin / Q000473:pathology
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; D004369:Pentetic Acid; D005682:Gadolinium; D019786:Gadolinium DTPA