[The storage technology of blood, the latest advances--cryopreservation of red blood cells].
In the field of red blood cell cryopreservation, the latest research informations were mainly divided into two parts as follows: 1) The improvement of the frozen storage bag. 2) The long-term storage of the frozen and thawed red blood cells. That was based on the research for changing the film of frozen storage bags from polyvinyl chloride to polyolefin. In consequent, the broken ratio of the bags in the period of frozen storage was expected to reduced, immediately. And this was studied for establishment of the closed bag system and introduction of the mannitol-adenine-phosphate(MAP) solution. From these results, it was made clear that the frozen and thawed red blood cells could be stored in MAP solution at 4 degrees C for 3 weeks.
Takayanagi
M
M
Aichi Prefecture Red Cross Blood Center.
Ishikawa
Y
Y
Nakashima
T
T
Ozawa
K
K
Yashiro
T
T
D015925:Cryopreservation / Q000379:methods*; D004912:Erythrocytes / Q000502:physiology*; D006801:Humans