Expression of Drosophila melanogaster gene encoding transcription factor GAGA is tissue-specific and temperature-dependent.
The GAGA factor (GAF) of Drosophila melanogaster encoded by the Trithorax-like gene is known to maintain expression of many Drosophila genes including homeotic ones, through configuration remodeling of local chromatin. The complicated transcript pattern of the GAF gene has been revealed at all stages of development. The study of GAF gene expression in whole flies and in salivary glands and in the brains with adjacent imaginal disks of the third instar larvae showed tissue-specific variations in transcript patterns and dependence of these patterns on the temperature of development (14-37 degrees C).
Baricheva
E M
EM
Group of Molecular Neurogenetics of Drosophila, Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Sciences, Novosibirsk. cellbiol@cgi.nsk.su
Katokhin
A V
AV
Perelygina
L M
LM
D000818:Animals; D002843:Chromatin / Q000502:physiology; D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000235:genetics / Q000502:physiology*; D018507:Gene Expression Regulation, Developmental; D017344:Genes, Insect; D018398:Homeodomain Proteins / Q000096:biosynthesis*; D007814:Larva; D009928:Organ Specificity; D015183:Restriction Mapping; D012469:Salivary Glands / Q000378:metabolism; D013696:Temperature; D014157:Transcription Factors / Q000096:biosynthesis*
D002843:Chromatin; D004268:DNA-Binding Proteins; D029721:Drosophila Proteins; D018398:Homeodomain Proteins; D014157:Transcription Factors; C063460:Trl protein, Drosophila