Clinical evaluation of Acuvue contact lenses with UV blocking characteristics.
BACKGROUND
In response to increasing scientific evidence which indicates that ultraviolet radiation (UVR) is a potential threat to ocular health, Acuvue contact lenses (Vistakon, Johnson & Johnson Vision Products Inc., Jacksonville, Florida) have been developed which incorporate an ultraviolet (UV) blocker within the lens polymer. Data are presented for the first clinical evaluation of Acuvue lenses with UV blocking characteristics.


METHODS
A double-masked, multicenter, prospective clinical trial involving 94 subjects was conducted. The study followed a randomized, parallel group design and consisted of 3 months of daily wear with two-weekly lens replacement. Two thirds of the subjects (61) wore the test lenses (Acuvue with UV blocker) and the remaining subjects (33) wore conventional Acuvue lenses (without UV blocker).


RESULTS
Biomicroscopic evaluations indicated that the performance of the test and control lenses was clinically similar. No clinically relevant differences between the test and control lenses were noted in the subjective assessments of vision, comfort, or handling. In addition, no differences were shown for surface deposition, lens durability, visual acuity, and subjective symptoms.


CONCLUSIONS
The study findings indicate that the addition of a UV blocker to Acuvue contact lenses has been achieved without affecting daily wear clinical performance. Because there is increasing evidence to suggest that the ocular tissues may be damaged by UVR, it is prudent for eye care practitioners to prescribe contact lenses that offer the benefits of both regular replacement and UV protection.
Hickson-Curran
S B
SB
Vistakon Clinical Research, Jacksonville, Florida, USA.
Nason
R J
RJ
Becherer
P D
PD
Davis
R A
RA
Pfeifer
J
J
Stiegemeier
M J
MJ
D000293:Adolescent; D000328:Adult; D003261:Contact Lenses / Q000009:adverse effects; D004311:Double-Blind Method; D005260:Female; D005374:Filtration; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009799:Ocular Physiological Phenomena; D011446:Prospective Studies; D011835:Radiation Protection; D012030:Refractive Errors / Q000628:therapy; D014466:Ultraviolet Rays