title: [Significance of left ventricular hypertrophy in primary hypertension and therapeutic modification by antihypertensive drugs].
abstract: Left ventricular hypertrophy (LVH) is one of the major cardiovascular risk factors. Without treatment a concentric form with left ventricular dysfunction develops characteristically into an excentric form with progressive heart failure. Many pathogenetically important factors are known. Treatment is possible with life-style modification and nearly all first-line antihypertensive drugs. It should aim at prevention or permanent normalisation of an existing LVH.
authors.affiliation: Klinische Forschung, Schwarz Pharma AG, Monheim (D).
authors.forename: A L
authors.initials: AL
authors.lastname: Schiemann
authors.forename: M
authors.initials: M
authors.lastname: Stimpel
mesh_terms: D000959:Antihypertensive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy* / Q000401:mortality; D017379:Hypertrophy, Left Ventricular / Q000188:drug therapy* / Q000209:etiology / Q000401:mortality; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents