title: Treatment of HIV-related scabies with emphasis on the efficacy of ivermectin.
abstract: Since the mid-1980s, worldwide reports confirm that scabies in individuals infected with the human immunodeficiency virus (HIV) result in a wide range of-clinical manifestations which differ from those seen in immunocompetent patients. There is also general agreement that HIV-related scabies is more difficult to treat. Oral ivermectin has been shown in several countries to be a safe and effective therapy. In otherwise healthy persons, one dose of 200 microg/kg is usually curative. In HIV-related scabies, one treatment may be curative but repeated doses may be required. Crusted scabies in these individual requires a combination of oral ivermectin, total body treatments with 5% permethrin cream, and keratolytic agents to hasten removal of crusts.
authors.affiliation: Department of Dermatology, University of Miami School of Medicine, FL 33101, USA.
authors.forename: D
authors.initials: D
authors.lastname: Taplin
authors.forename: T L
authors.initials: TL
authors.lastname: Meinking
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy*; D000284:Administration, Oral; D002986:Clinical Trials as Topic; D005260:Female; D006801:Humans; D007306:Insecticides / Q000627:therapeutic use*; D007559:Ivermectin / Q000627:therapeutic use*; D008297:Male; D012532:Scabies / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D007306:Insecticides; D007559:Ivermectin