title: Molecular cloning and expression of mouse homologue of SFA-1/PETA-3 (CD151), a member of the transmembrane 4 superfamily.
abstract: We have isolated mouse SFA-1 (CD151) cDNA from a mouse myelomonocytic leukemia cell line, WEHI-3. Mouse CD151 mRNA comprises approximately 1.8 kb, has 253 amino acid residues with 93% identity to human CD151 and contains four putative transmembrane domains, a number of cysteine residues and one potential N-glycosylation site located at a site corresponding to that in human CD151. Mouse CD151 gene expression was observed in many cell types, but was either absent or present at a low level in brain and lymphoid cells and tissues, including thymus and spleen. The expression patterns of mouse and human CD151 genes are similar.
authors.affiliation: First Department of Internal Medicine, Ehime University, School of Medicine, Shigenobu, Japan. hitoshih@m.ehime-u.ac.jp
authors.forename: H
authors.initials: H
authors.lastname: Hasegawa
authors.forename: H
authors.initials: H
authors.lastname: Watanabe
authors.forename: T
authors.initials: T
authors.lastname: Nomura
authors.forename: Y
authors.initials: Y
authors.lastname: Utsunomiya
authors.forename: K
authors.initials: K
authors.lastname: Yanagisawa
authors.forename: S
authors.initials: S
authors.lastname: Fujita
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D015703:Antigens, CD / Q000235:genetics*; D001483:Base Sequence; D002460:Cell Line; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000302:isolation & purification; D015870:Gene Expression; D051379:Mice; D008807:Mice, Inbred BALB C; D008969:Molecular Sequence Data; D012313:RNA / Q000302:isolation & purification; D017386:Sequence Homology, Amino Acid; D060185:Tetraspanin 24; D014407:Tumor Cells, Cultured
chemical_list: D015703:Antigens, CD; C554715:CD151 protein, human; C554716:Cd151 protein, mouse; D018076:DNA, Complementary; D060185:Tetraspanin 24; D012313:RNA