title: Scarred for life?
abstract: Acne vulgaris is a common inflammatory dermatosis capable of producing significant psychological and physical scarring. The following work describes the benefit of using a questionnaire as a clinical tool to identify acne patients who have developed psychological sequelae as a result of the disease process. In addition, the benefit of isotretinoin on psychological impact has also been highlighted by this work. A prospective clinical study examines the early use of isotretinoin in acne and demonstrates the beneficial effect of early therapy in minimising acne scarring. In summary, oral isotretinoin (Roaccutane/Accutane) provides a very effective therapy to prevent acne patients being 'scarred for life'!
authors.affiliation: Department of Dermatology, Leeds Foundation for Dermatology Research, Harrogate District Hospital, UK.
authors.forename: A M
authors.initials: AM
authors.lastname: Layton
authors.forename: D
authors.initials: D
authors.lastname: Seukeran
authors.forename: W J
authors.initials: WJ
authors.lastname: Cunliffe
mesh_terms: D000152:Acne Vulgaris / Q000150:complications / Q000188:drug therapy* / Q000523:psychology*; D000223:Adaptation, Psychological; D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D002921:Cicatrix / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage* / Q000627:therapeutic use; D007641:Keratolytic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D008297:Male; D017060:Patient Satisfaction; D011446:Prospective Studies; D011788:Quality of Life; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires
chemical_list: D007641:Keratolytic Agents; D015474:Isotretinoin