Substrate for rapid feedforward inhibition of the auditory forebrain.
A sizeable, feedforward, GABAergic projection exists from the inferior colliculus to the medial geniculate body in cats. We compared the dimensions of GABA-immunoreactive and non-immunoreactive axons in the brachium of the cat inferior colliculus, and demonstrate that GABA-immunoreactive axons are among the largest of brachial axons. We propose that, based on their large size, GABAergic tectothalamic axons provide a substrate for rapid feedforward inhibition of geniculate neurons.
Saint Marie
R L
RL
Neuroanatomy Department, House Ear Institute, Los Angeles, CA 90057, USA. rstmarie@hei.org
Stanforth
D A
DA
Jubelier
E M
EM
D000818:Animals; D001369:Axons / Q000502:physiology / Q000648:ultrastructure; D001917:Brachial Plexus / Q000166:cytology / Q000502:physiology; D002415:Cats; D048429:Cell Size; D005829:Geniculate Bodies / Q000166:cytology / Q000502:physiology*; D007150:Immunohistochemistry; D007245:Inferior Colliculi / Q000166:cytology / Q000502:physiology*; D009186:Myelin Sheath / Q000502:physiology / Q000648:ultrastructure; D016548:Prosencephalon / Q000166:cytology / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism / Q000502:physiology
D005680:gamma-Aminobutyric Acid