Vitamin E (alpha-tocopherol) enhances arachidonic acid release in rat heart myoblastic cells through the activation of cytosolic phospholipase A2.
Tran
K
K
Faculty of Medicine, University of Manitoba, Winnipeg, Canada.
Lee
E
E
Wong
J
J
Man
R Y
RY
Jay
F T
FT
Chan
A C
AC
Choy
P C
PC
D000818:Animals; D016718:Arachidonic Acid / Q000378:metabolism*; D000001:Calcimycin / Q000494:pharmacology; D003600:Cytosol / Q000201:enzymology; D004789:Enzyme Activation / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006321:Heart / Q000187:drug effects* / Q000502:physiology; D007211:Indoles / Q000494:pharmacology; D007476:Ionophores / Q000494:pharmacology; D007527:Isoenzymes / Q000502:physiology*; D009124:Muscle Proteins / Q000502:physiology*; D009206:Myocardium / Q000201:enzymology*; D010741:Phospholipases A / Q000502:physiology*; D054467:Phospholipases A2; D011493:Protein Kinase C / Q000037:antagonists & inhibitors / Q000502:physiology; D051381:Rats; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D014810:Vitamin E / Q000494:pharmacology*
D004791:Enzyme Inhibitors; D007211:Indoles; D007476:Ionophores; D007527:Isoenzymes; D009124:Muscle Proteins; D014810:Vitamin E; D016718:Arachidonic Acid; D000001:Calcimycin; D011493:Protein Kinase C; D010741:Phospholipases A; D054467:Phospholipases A2; D013755:Tetradecanoylphorbol Acetate; C064758:Ro 31-8220