[A change in the composition of cardiac membrane phospholipids in the process of nonspecific myocardial adaptation].
The content and composition of cardiac phospholipids (PL) were investigated under the action of a new neuroactive inhibitory amino acid designed on the molecular basis. I.p. injection of the drug in rats was shown to cause no changes in PL levels and to alter the composition of metabolically important PL fractions (phosphatidylinositol, phosphatidylserine). These changes may be involved in the nonspecific adaptation of the heart to damaging exposures and in the cardioprotective action of substances, such as antihypoxants.
Sapronov
N S
NS
Torkunov
P A
PA
Novoselova
N Iu
NIu
Nalivaeva
N N
NN
D000222:Adaptation, Physiological; D000818:Animals; D008297:Male; D008563:Membrane Lipids / Q000378:metabolism*; D009206:Myocardium / Q000378:metabolism*; D010743:Phospholipids / Q000378:metabolism*; D051381:Rats
D008563:Membrane Lipids; D010743:Phospholipids