[Relationship between iron status and diet in 410 hyperlipidemic patients].
In order to examine the influence of a low-fat diet on iron status, we carried out a study which involved 410 out-patients with hyperlipidaemia, i.e. 256 men and 154 women. Serum iron was positively correlated with protein intake (p = 0.11; p < 0.05) and transferrin saturation was inversely correlated with fat intake (p = - 0.12; p < 0.05). A positive iron balance (serum iron > 27 mumol/l and transferrin saturation > 45%) was found in 1.6% of the male subjects, a frequency which could be explained by the presence of the hemochromatosis genes. A negative iron balance (serum iron < 10 mumol/l and tranferrin saturation < 15%) was found in 13.7% for women aged 21-49 yr, 3.7% for women aged 50-77 yr and 3.5% for men aged 21-77 yr. We found no association between low-fat diet and iron deficiency. Men with iron deficiency had 12% decrease in total calorie intake compared to the Recommended Dietary Allowance. Our results do not provide evidence that hypolipidemic diet is associated with a high frequency of iron deficiency.
Marchand
C
C
Laboratoire Central de Biochimie, Groupe Hospitalier Pitié-Salpétrière, Paris Cedex 13, France.
Bruckert
E
E
Jacob
N
N
Turpin
G
G
Foglietti
M J
MJ
D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D018752:Diet, Fat-Restricted; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood* / Q000178:diet therapy*; D007501:Iron / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D014168:Transferrin / Q000032:analysis
D014168:Transferrin; D007501:Iron