Correlation between central somatosensory conduction time, blood flow velocity, and delayed cerebral ischemia after aneurysmal subarachnoid hemorrhage.
In this retrospective study of 67 aneurysmal patients, the predictive role of central conduction time (CCT) on vasospasm occurrence evaluated by means of transcranial Doppler sonography (TCD) and the correlation of CCT to blood flow velocity measured simultaneously in postoperative course were studied. Data about the clinical state of patients at the time of admission (Hunt Hess scale), severity of subarachnoidal hemorrhage on initial CT scan (Fisher grade), timing of surgery (acute or delayed), outcome (Glasgow Outcome Scale), severity of vasospasm graded by highest mean blood flow velocity (BFV) during the entire clinical course and CCT values measured at admission (preoperatively), then postoperatively (one day after surgery) and simultaneously with later TCD investigations were collected from the files. Interhemispheric difference of CCT was also calculated. The results showed that CCT at admission was not predictive for vasospasm. CCT measured either at admission or on the first postoperative day did not differ significantly in the different grades of vasospasm. Similar results were obtained in the acute and in the late operated group of patients. The results also suggest that increased CCT and interhemispheric difference at the time of admission indicate a worse prognosis, but this can be related to higher surgical risk rather than to a higher incidence of late ischemic deterioration. Simultaneous CCT and TCD examinations demonstrated that coincident and statistically significant (p < 0.01) increase of actual CCT (6.7 msec) was found only in the severe grade of vasospasm (BFV 200 cm/s). The authors discuss the role of CCT and TCD monitoring in the management of aneurysmal subarachnoid hemorrhage.
Szabó
S
S
Department of Neurosurgery, Medical School University of Debrecen, Hungary.
Mikó
L
L
Novák
L
L
Rózsa
L
L
Székely
G
G
D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D002545:Brain Ischemia / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D002560:Cerebrovascular Circulation; D005073:Evoked Potentials, Somatosensory; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013003:Somatosensory Cortex / Q000502:physiology; D013345:Subarachnoid Hemorrhage / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D014463:Ultrasonography