title: [Disproportion in diameter of the cardiac chambers and great arteries in the fetus. Contribution to the prenatal diagnosis of coarctation of the aorta].
abstract: The aim of this study was to identify simple echocardiographic criteria suggesting the presence of coarctation of the aorta in the antenatal period. This was a retrospective cooperative study of 43 cases of foetal echocardiography referred to a paediatric cardiologist for abnormal dimensions of the left cardiac chambers and vessels compared with 102 control foetus. Eighteen (41.8%) had abnormalities of the aortic arch at birth. Thirteen of the 18 (72%) neonates had aortic arch abnormalities when disequilibrium with a small left heart was observed before 25 weeks amenorrhea. The ratio between the right and left ventricular dimensions was abnormally high in foetus with functional disequilibrium similar to the foetus with coarctation: the difference between the two groups was not significant. The ratio of pulmonary artery to aortic dimension was higher in the foetus with coarctation of the aorta than with functional disequilibrium. The difference was significant: p < 0.0001. The diameter of the aortic arch in foetus with a future coarctation was much smaller than the mean of the controls, except in 4 cases. The majority of the foetus without left-sided obstacles at birth had normal aortic arches. An early disequilibrium, a high pulmonary artery/aortic ratio and the small size of the aortic ischmus were the main elements suggestive of abnormalities of the aortic arch, especially in the early prenatal period.
authors.affiliation: Service de pédiatrie et génétique médicale, hôpital Charles-Nicolle, Rouen.
authors.forename: N
authors.initials: N
authors.lastname: David
authors.forename: M
authors.initials: M
authors.lastname: Iselin
authors.forename: G
authors.initials: G
authors.lastname: Blaysat
authors.forename: I
authors.initials: I
authors.lastname: Durand
authors.forename: A
authors.initials: A
authors.lastname: Petit
mesh_terms: D001013:Aorta, Thoracic / Q000000981:diagnostic imaging; D001017:Aortic Coarctation / Q000000981:diagnostic imaging*; D016022:Case-Control Studies; D005314:Embryonic and Fetal Development; D005260:Female; D005865:Gestational Age; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011651:Pulmonary Artery / Q000000981:diagnostic imaging; D012189:Retrospective Studies; D016216:Ultrasonography, Prenatal