title: [Familial multiple sclerosis: study of 2 cases of a northern African family].
abstract: We report two cases of multiple sclerosis (MS) beginning in a mother and her daughter at 40 years of age. The diagnosis of MS was certain for both patients (Poser et al., 1983). Clinical features, evolution and response to treatment are comparable in both cases. Cerebral and medullar cord MRI and/or CT Scan showed characteristic lesions of demyelination on periventricular white matter, corpus callosum and brainstem.
authors.affiliation: Service de Neurologie, EPS Charles Nicolle, Tunis, Tunisie.
authors.forename: I B
authors.initials: IB
authors.lastname: Ben Hamouda
authors.forename: A
authors.initials: A
authors.lastname: Mrabet
authors.forename: M
authors.initials: M
authors.lastname: Fredj
authors.forename: R
authors.initials: R
authors.lastname: Gouilder
mesh_terms: D000328:Adult; D000352:Africa, Northern / Q000453:epidemiology / Q000208:ethnology; D004198:Disease Susceptibility; D005260:Female; D005819:Genetic Markers; D006801:Humans; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000453:epidemiology / Q000235:genetics*; D010375:Pedigree; D010641:Phenotype; D013997:Time Factors
chemical_list: D005819:Genetic Markers