[Hyperbaric oxygenation in inhalation poisoning with substances with varying mechanisms of action (styrene, toluene and carbon monoxide].
The disintoxicating mechanisms of hyperbaric oxygenation (HBO) on inhalation intoxication with substances from different chemical classes (aromatic hydrocarbons and carbon oxide) were investigated in rats. HBO was demonstrated to have a significant effect on the whole array of the studied parameters (physiological, morphological, and biochemical ones), on lipid peroxidation (LP) in particular. The levels of LP products in the liver, brain, blood became normal and the antioxidative system was stimulated as well. The most striking effect of HBO therapy on inhalation of toxic agents taken in the mean or maximum lethal concentrations was noted in the use of carbon oxide.
Fertikova
T E
TE
Faustov
A S
AS
Leonov
A N
AN
D000280:Administration, Inhalation; D000818:Animals; D002249:Carbon Monoxide Poisoning; D006931:Hyperbaric Oxygenation; D051381:Rats; D020058:Styrene; D013343:Styrenes / Q000506:poisoning*; D014050:Toluene / Q000506:poisoning*
D013343:Styrenes; D014050:Toluene; D020058:Styrene