[Pseudotumor form of hepatic distomatosis: successful treatment with praziquantel].
Human Fasciola hepatica infection is usually discovered either early, during the acute (invasive) phase, or in the advanced phase, which is characterized by biliary complications. We report a case of liver distomatosis with nodular intra-hepatic lesions in a 58-year-old woman. Radiological investigations showed 3 nodular lesions in the VII segment, which were difficult to distinguish from liver metastases or liver abscesses. Distomatosis serology was positive with passive hemagglutination. After a 5-day treatment with praziquantel, clinical symptoms resolved quickly while serological tests became negative. Radiological images slowly decreased to a calcified scar at 13 months. No side-effects were noted. Praziquantel, whose efficacy in the common presentations of liver distomatosis has recently been demonstrated, also seems effective and well tolerated in case of nodular intra-hepatic lesions.
Queneau
P E
PE
Service de Gastroentérologie, CHRU Jean Minjoz, Besançon.
Koch
S
S
Bresson-Hadni
S
S
Bartholomot
B
B
Arbez-Gindre
F
F
Heyd
B
B
Miguet
J P
JP
D000980:Antiplatyhelmintic Agents / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D005211:Fascioliasis / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008109:Liver Diseases, Parasitic / Q000175:diagnosis; D008113:Liver Neoplasms / Q000175:diagnosis; D008875:Middle Aged; D011223:Praziquantel / Q000627:therapeutic use*
D000980:Antiplatyhelmintic Agents; D011223:Praziquantel