title: Direct-current cardioversion of atrial tachyarrhythmias under oral flecainide therapy.
abstract: Results of direct-current cardioversion of 48 patients with atrial arrhythmia taking oral flecainide were compared with those of 96 control-matched patients. After completion of 3 shocks, 98% of flecainide patients were converted versus 78% of control patients (p <0.01). Thus, despite an experimental increase in defibrillation threshold, flecainide given before cardioversion seems to have a beneficial effect.
authors.affiliation: Department of Cardiology, Lariboisière University Hospital, Paris, France.
authors.forename: J F
authors.initials: JF
authors.lastname: Leclercq
authors.forename: J
authors.initials: J
authors.lastname: Bizot
authors.forename: P
authors.initials: P
authors.lastname: Attuel
authors.forename: P
authors.initials: P
authors.lastname: Coumel
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002908:Chronic Disease; D004554:Electric Countershock; D004562:Electrocardiography; D005260:Female; D005424:Flecainide / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013610:Tachycardia / Q000628:therapy*
chemical_list: D000889:Anti-Arrhythmia Agents; D005424:Flecainide