Pathologic conditions in the small bowel: findings at fat-suppressed gadolinium-enhanced MR imaging with an optimized suspension of oral magnetic particles.
Depiction of small-bowel pathologic conditions was optimized with use of a negative luminal contrast agent, spectral fat suppression, and gadolinium enhancement in an excised gut phantom. The method was applied in nine patients in conjunction with standard enteroclysis examinations. Bulk susceptibility effects of oral magnetic particles were canceled with use of a diamagnetic methylcellulose suspension. In the ileum, fat suppression and contrast between bowel wall and lumen was judged good or excellent in eight and nine patients, respectively. In eight of nine patients, additional mesenteric findings were depicted.
Faber
S C
SC
Department of Diagnostic Radiology, Klinikum Grosshadern, University of Munich, Germany.
Stehling
M K
MK
Holzknecht
N
N
Gauger
J
J
Helmberger
T
T
Reiser
M
M
D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000818:Animals; D002417:Cattle; D003287:Contrast Media / Q000008:administration & dosage*; D004338:Drug Combinations; D005260:Female; D052203:Ferrosoferric Oxide; D005682:Gadolinium / Q000008:administration & dosage*; D019786:Gadolinium DTPA; D006801:Humans; D066298:In Vitro Techniques; D007410:Intestinal Diseases / Q000175:diagnosis*; D007421:Intestine, Small / Q000473:pathology*; D007501:Iron / Q000008:administration & dosage*; D008279:Magnetic Resonance Imaging; D008297:Male; D008536:Meglumine / Q000008:administration & dosage*; D008875:Middle Aged; D009942:Organometallic Compounds / Q000008:administration & dosage*; D010087:Oxides / Q000008:administration & dosage*; D004369:Pentetic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives*
D003287:Contrast Media; D004338:Drug Combinations; D009942:Organometallic Compounds; D010087:Oxides; D008536:Meglumine; D004369:Pentetic Acid; D005682:Gadolinium; D007501:Iron; D019786:Gadolinium DTPA; D052203:Ferrosoferric Oxide