title: Characterization of mitochondrial DNA and Y-chromosome haplotypes in a Uruguayan population of African ancestry.
abstract: We used a set of informative mtDNA and Y-chromosome-specific markers to determine the origin of maternal and paternal lineages in a sample of 41 Uruguayan black individuals. We found that 20 maternal lineages were African, 13 were Amerindian, and 5 were Caucasian. In three individuals we were unable to determine the ethnic origin of the mtDNA lineages. Of the 22 males analyzed we found 4 Y chromosomes of African origin, 5 of Caucasian origin, and 13 of undetermined ancestry. Our results suggest that mtDNA and Y-chromosome-specific DNA variants may be a useful tool in determining the level of mtDNA and Y chromosome ethnic introgression in a population of a given ethnic origin.
authors.affiliation: IMBICE, La Plata, Argentina.
authors.forename: C M
authors.initials: CM
authors.lastname: Bravi
authors.forename: M
authors.initials: M
authors.lastname: Sans
authors.forename: G
authors.initials: G
authors.lastname: Bailliet
authors.forename: V L
authors.initials: VL
authors.lastname: Martínez-Marignac
authors.forename: M
authors.initials: M
authors.lastname: Portas
authors.forename: I
authors.initials: I
authors.lastname: Barreto
authors.forename: C
authors.initials: C
authors.lastname: Bonilla
authors.forename: N O
authors.initials: NO
authors.lastname: Bianchi
mesh_terms: D000349:Africa / Q000208:ethnology; D044383:Black People / Q000235:genetics*; D004272:DNA, Mitochondrial / Q000032:analysis / Q000235:genetics*; D005260:Female; D005819:Genetic Markers; D006239:Haplotypes / Q000235:genetics; D006801:Humans; D007198:Indians, North American / Q000235:genetics*; D008297:Male; D010802:Phylogeny; D014583:Uruguay; D044465:White People / Q000235:genetics*; D014998:Y Chromosome / Q000235:genetics*
chemical_list: D004272:DNA, Mitochondrial; D005819:Genetic Markers