[Immunologic bases of graft vs. host disease: 1997].
The development of a graft-versus-host reaction after hematopoietic stem cell transplantation is an important determinant of the transplant outcome. The existence of subsets of CD4+ helper T-lymphocytes that differ in their cytokine secretion patterns and effector functions provides a framework for better understanding and improved management of the graft-versus-host reaction. It should allow improved prevention and treatment of graft-versus-host disease and the development of new strategies to enhance a graft-versus-leukemic relapse after transplantation.
Uher
F
F
Kisérletes Csontvelötranszplantációs Laboratórium, Országos Haematológiai és Immunológiai Intézet, Budapest.
D006086:Graft vs Host Disease / Q000276:immunology*; D006680:HLA Antigens / Q000276:immunology; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D011153:Population; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*
D006680:HLA Antigens