title: [Epiduritis after long-term pain therapy with an epidural catheter--review of the literature with a current case report].
abstract: Patients suffering from vascular disease are often a challenge for the acute pain service. Ischaemia, impaired wound healing, stump and phantom limb pain often require a complex analgesic regimen. Invasive measures such as spinal or epidural catheters can be very helpful but carry the risk of infection, as shown by this case report. A 53-year-old woman with a ten-year history of diabetes developed arterial vascular disease. Her right lower leg had been amputated two years previously. She was now admitted with necroses of the left forefoot. A bypass operation was performed under general anaesthesia. Because of intractable ischaemic pain, she was provided with an epidural catheter by the acute pain service. The bypass occluded, however, and a few days later her left lower leg also had to be amputated, this operation being performed under epidural anaesthesia with bupivacaine. The catheter was subsequently used for postoperative pain control and as a means to prevent phantom limb pain. When signs of superficial catheter infection were noticed days later, the catheter was immediately removed. Intractable pain then developed in the left leg which could not be sufficiently controlled with opioids and NSAIDs, and so a second epidural catheter was inserted one segment rostrally. Several days later the infected vascular prosthesis had to be removed followed by amputation of the thigh, this operation also being performed in epidural anaesthesia. Eleven days after insertion of the first epidural catheter, the patient complained of low back pain and headache. Examination by a neurologist revealed no signs of intraspinal infection. The second epidural catheter dislocated at this point in time and it was decided to introduce a third one, this being the only means to treat the otherwise intractable stump pain. Ten days later meningism, Kernig's sign and leucocytosis developed. NMR tomography detected intraspinal fluid in the epidural space at the dorsal border of the spinal canal. A hemilaminectomy was performed. The spinal epidural space showed signs of inflammation of the adipose tissue, but no pus. A little necrotic material and residues of an old haematoma were removed and the epidural space was lavaged. Specimens taken from the epidural material revealed colonisation with staphylococcus epidermidis, which was sensitive to the broad spectrum antibiotics formerly given to the patient to treat the infection in the left stump. By the next day, all signs of epiduritis had disappeared and the patient recovered completely.
authors.affiliation: Universitätsklinik für Anästhesiologie, Klinikum der Universität Ulm.
authors.forename: H
authors.initials: H
authors.lastname: Michel
authors.forename: P
authors.initials: P
authors.lastname: Steffen
authors.forename: T
authors.initials: T
authors.lastname: Weichel
authors.forename: W
authors.initials: W
authors.lastname: Seeling
mesh_terms: D015360:Analgesia, Epidural / Q000295:instrumentation*; D002408:Catheters, Indwelling; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D010591:Phantom Limb / Q000188:drug therapy*; D013203:Staphylococcal Infections / Q000209:etiology* / Q000628:therapy; D013212:Staphylococcus epidermidis