title: Multivalent vaccines: prospects and challenges.
abstract: The advantages and disadvantages of combination vaccines are set out with a clear indication that, although there are many (described and discussed) influences on in the immunogenicity of a vaccine it would still be of considerable value to be able to deliver such materials with the minimum number of needle-stick injections. Such a situation may become facilitated in the future as vaccines based on plasmid DNA become available; a prospect which is examined in outline in the final section.
authors.affiliation: University of Surrey, Guildford, UK.
authors.forename: R E
authors.initials: RE
authors.lastname: Spier
mesh_terms: D017277:Drug Approval; D015195:Drug Design; D004345:Drug Industry / Q000639:trends; D013601:T-Lymphocytes / Q000276:immunology; D014612:Vaccines; D017778:Vaccines, Combined; D019444:Vaccines, DNA
chemical_list: D014612:Vaccines; D017778:Vaccines, Combined; D019444:Vaccines, DNA