title: [Participation of the follicular fluid in follicular development, oocyte maturation and spermatic function].
abstract: Follicular fluid (FF) is of great importance in Assisted Procreation Programmes, because it constitutes the micro-environment of the follicle that regulates the development of the oocyte and participates in the capacitation of the spermatozoa. The biochemical composition of FF is influenced by the state of follicle maturation and reciprocally the content of the fluid predicts the success of the subsequent follicular maturation and pregnancy. In most of the species the high concentrations of estradiol are common in the follicles of intermediate maturity, the progesterone in the mature ones and the androgens in the atresics ones. Estradiol concentration is associated with the fertilizing capacity of the oocytes and its metabolites stimulate the progesterone production. Moreover, the FF regulates the action of the gonadotrophins, because it contains factors that help the union of these with its receptor. The FF contributes providing factors that inhibit and stimulate the meiosis. It contains factors that stimulates oocyte maturation, or that block the ability of the cortical granules to modify the components of the pellucid zone. The exposition of spermatozoons with this fluid helps the acrosomal reaction, the spermatic motility and the ovum penetration.
authors.affiliation: Unidad de Investigación Médica en Bioquímica, Hospital de Especialidades, Centro Médico Nacional Siglo XXI A.P., México, D.F.
authors.forename: G
authors.initials: G
authors.lastname: Durán Reyes
authors.forename: A M
authors.initials: AM
authors.lastname: Rosales
authors.forename: J J
authors.initials: JJ
authors.lastname: Hicks Gómez
mesh_terms: D006063:Chorionic Gonadotropin / Q000502:physiology; D005260:Female; D015571:Follicular Fluid / Q000502:physiology*; D005498:Follicular Phase; D006801:Humans; D007315:Insemination, Artificial; D008297:Male; D009865:Oocytes / Q000502:physiology*; D011247:Pregnancy; D013094:Spermatozoa / Q000502:physiology
chemical_list: D006063:Chorionic Gonadotropin