title: Model-free reconstruction of three-dimensional myocardial strain from planar tagged MR images.
abstract: A technique is presented for reconstructing a three-dimensional myocardial strain map from a set of parallel-tagged MR images. Radial strains were reconstructed from in vivo data from an anesthetized dog with values between .05 and .1 with a precision of +/- .003 for a tag detection accuracy of .1 mm and a tag spacing of 2.5 mm. The reconstruction spatial resolution was demonstrated by reconstructing a localized displacement abnormality. In the circumferential direction, the abnormality that resulted in 50% displacement attenuation had a full width at half maximum of 5.4 +/- .4 mm (mean +/- SD). Graphs are presented showing the relationship between the size of an abnormality and the ability of the method to reconstruct that abnormality. The combination of high resolution parallel-tagged MR images and the model-free, coordinate system-free strain reconstruction technique presented in this paper is capable of producing accurate, high resolution strain maps of the myocardium.
authors.affiliation: Electrical Engineering Department, Auburn University, AL 36849-5201, USA.
authors.forename: T S
authors.initials: TS
authors.lastname: Denney
authors.forename: E R
authors.initials: ER
authors.lastname: McVeigh
mesh_terms: D000465:Algorithms; D000818:Animals; D004285:Dogs; D017352:Echo-Planar Imaging / Q000295:instrumentation / Q000379:methods*; D006321:Heart / Q000033:anatomy & histology / Q000502:physiology*; D007089:Image Enhancement / Q000379:methods*; D009010:Monte Carlo Method; D012680:Sensitivity and Specificity; D013314:Stress, Mechanical