Tardive akathisia due to sulpiride.
A 56 year-old woman who suffered from parkinsonism, oro-lingual dyskinesia (OLD) and tardive akathisia (TA) due to sulpiride is reported. OLD and TA appeared after sulpiride withdrawal. The patient was successfully treated with tetrabenazine even a mild parkinsonism was present. TA seems to be related with an apparent dopaminergic hyperactivity and it has to be differentiated of other neuroleptic-induced movement disorders such as restless legs syndrome in order of an appropriate treatment. Sulpiride has the same possible side effects than classic neuroleptics.
López de Munain
A
A
Neurology Department, Hospital Nuestra Señora, de Aranzazu, San Sebastian, Spain.
Poza
J J
JJ
Gorospe
A
A
Arce
A
A
Martí Massó
J F
JF
D017109:Akathisia, Drug-Induced / Q000209:etiology*; D018687:Antidepressive Agents, Second-Generation / Q000009:adverse effects*; D014150:Antipsychotic Agents / Q000009:adverse effects*; D018492:Dopamine Antagonists / Q000009:adverse effects*; D004409:Dyskinesia, Drug-Induced / Q000209:etiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D010302:Parkinson Disease, Secondary / Q000209:etiology; D013469:Sulpiride / Q000009:adverse effects*
D018687:Antidepressive Agents, Second-Generation; D014150:Antipsychotic Agents; D018492:Dopamine Antagonists; D013469:Sulpiride