[Prognostic significance of desmoplasia in breast carcinoma. A preliminary clinical study].
This study carried on 61 patients with breast cancer confirmed the biological assumption of a higher malignancy in tumors with strong desmoplastic reaction. Patients in stage II A, II B and III presenting a marked desmoplastic reaction have a shorter DFS (disease free survival). Therefore, desmoplastic reaction may be considered a marker of local malignancy and metastatic process.
Mezi
S
S
III Clinica Chirurgica Generale e Terapia Chirurgica, Università degli Studi La Sepienza, Roma.
Aloise
G
G
Marzullo
A
A
Marchei
P
P
Di Benedetto
A
A
Modica
A
A
Vasaturo
F
F
Modesti
M
M
D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000473:pathology; D011379:Prognosis; D013997:Time Factors
D014408:Biomarkers, Tumor