title: Desmoplastic fibroma of the temporal bone.
abstract: BACKGROUND
  Desmoplastic fibroma is a benign, locally aggressive, intraosseous neoplasm with a propensity for local recurrence. Desmoplastic fibroma most commonly originates within the mandible (70% of cases), and long bones with rare lesions reported in the maxillary, frontal, and parietal bones. We report two patients with desmoplastic fibroma arising within the temporal bone.
  
  
  METHODS
  Case report and literature review.
  
  
  METHODS
  Two patients with desmoplastic fibroma with intracranial and extra cranial growth patterns are presented. Both were young females with aural fullness and decreased hearing.
  
  
  METHODS
  Diagnostic and therapeutic.
  
  
  RESULTS
  Both tumors were surgically extirpated and the patients have remained disease free for 18-48 months. Neither tumor expressed estrogen or progesterone receptors.
  
  
  CONCLUSIONS
  Desmoplastic fibroma is a highly invasive local destructive lesion which is best treated by nondestructive surgical intervention. Immunohistochemical analysis may demonstrate hormonal receptors, in which case Tamoxifen may reduce recurrence.
authors.affiliation: Department of Otolaryngology, University of Cincinnati College of Medicine, OH 45267-0528, USA.
authors.forename: M L
authors.initials: ML
authors.lastname: Pensak
authors.forename: B R
authors.initials: BR
authors.lastname: Nestok
authors.forename: H
authors.initials: H
authors.lastname: Van Loveren
authors.forename: K A
authors.initials: KA
authors.lastname: Shumrick
mesh_terms: D000328:Adult; D005260:Female; D018220:Fibroma, Desmoplastic / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D012888:Skull Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D013701:Temporal Bone / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed