title: The regurgitation of large vitreous injections.
abstract: The same quantity of fluorescein labelled dextran was injected into the vitreous humor of 5 rabbits; in one eye, dissolved in 10 microliters solution and in the other, 100 microliters. The level of fluorescence in the two eyes was compared a few days later and found to average only 12% less with the larger volume. It is concluded that regurgitation through the needle hole can be ignored in spite of the very high intraocular pressure created by the 100 microliter injection.
authors.affiliation: Department of Ophthalmology, College of Physicians and Surgeons, Columbia University, New York, New York, USA.
authors.forename: D M
authors.initials: DM
authors.lastname: Maurice
mesh_terms: D000818:Animals; D003911:Dextrans; D005260:Female; D016650:Fluorescein-5-isothiocyanate / Q000031:analogs & derivatives; D008845:Microinjections; D011817:Rabbits; D014822:Vitreous Body / Q000378:metabolism*
chemical_list: D003911:Dextrans; C015219:fluorescein isothiocyanate dextran; D016650:Fluorescein-5-isothiocyanate