Laryngeal evoked brainstem responses in humans: a preliminary study.
Laryngeal evoked brainstem responses (LBRs) were recorded in normal human subjects in an attempt to develop a central laryngeal function test and enhance our understanding of neurolaryngologic disorders. The results showed that the human LBR consists of five positive peaks and five negative peaks reproducible within 10 ms after a vibratory stimulation to the superior laryngeal nerve (SLN). The waveform reproducibility was verified by blocking the SLN and topically anesthetizing the hypopharyngeal cavity. The morphology and latency of peak 5 were similar to results obtained in animal LBR experiments. It was concluded that a vibratory stimulation to the SLN was a noninvasive method to elicit far-field potentials from the central laryngeal pathway. These findings encourage further effort to establish normative data and explore clinical correlations.
Yin
S S
SS
Department of Otolaryngology-Head and Neck Surgery, Louisiana State University Medical Center in Shreveport, 71130-3932, U.S.A.
Qiu
W W
WW
Stucker
F J
FJ
Hoasjoe
D K
DK
Aarstad
R F
RF
Batchelor
B M
BM
D000328:Adult; D000779:Anesthetics, Local / Q000008:administration & dosage; D000818:Animals; D001933:Brain Stem / Q000502:physiology*; D003389:Cranial Nerve Diseases / Q000175:diagnosis / Q000503:physiopathology; D004566:Electrodes; D005071:Evoked Potentials / Q000187:drug effects / Q000502:physiology*; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000503:physiopathology; D006801:Humans; D007013:Hypopharynx / Q000187:drug effects / Q000294:innervation; D007818:Laryngeal Diseases / Q000175:diagnosis / Q000503:physiopathology; D007823:Laryngeal Nerves / Q000187:drug effects / Q000502:physiology*; D007830:Larynx / Q000502:physiology*; D008012:Lidocaine / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009407:Nerve Block; D009434:Neural Pathways / Q000502:physiology; D010812:Physical Stimulation; D011930:Reaction Time; D015203:Reproducibility of Results; D014732:Vibration
D000779:Anesthetics, Local; D008012:Lidocaine