Transient elevation of aldosterone levels in perinatal asphyxia.
We measured plasma aldosterone levels in cord blood and peripheral blood collected 18-24 h after birth in 19 asphyxiated and 19 normal term newborn infants. The asphyxiated newborn infants had significantly higher aldosterone levels in cord blood than the normal newborn infants. At 18-24 h after birth there was no difference between the groups with respect to aldosterone levels. There was a positive significant correlation between aldosterone levels and PCO2 in cord blood by multiple linear regression analysis. There is a transient elevation of aldosterone levels in perinatal asphyxia.
Pereira
D N
DN
Department of Pediatrics, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Procianoy
R S
RS
D000450:Aldosterone / Q000097:blood*; D001238:Asphyxia Neonatorum / Q000097:blood*; D005312:Fetal Blood / Q000737:chemistry; D006801:Humans; D007231:Infant, Newborn; D011446:Prospective Studies; D012044:Regression Analysis; D013997:Time Factors
D000450:Aldosterone