Human chondrosarcoma cells stably transfected with a stromelysin (MMP-3) promoter reporter construct provide a method of assessing transcriptional inhibitors.
Janusz
M J
MJ
Hoechst Marion Roussel Pharmaceuticals, Cincinnati, OH 45215, USA. michaeljanusz@hmri.com
Hare
C M
CM
Durham
S L
SL
Woessner
R D
RD
D001859:Bone Neoplasms / Q000201:enzymology*; D002813:Chondrosarcoma / Q000201:enzymology*; D003907:Dexamethasone / Q000494:pharmacology; D006801:Humans; D007375:Interleukin-1 / Q000494:pharmacology; D019278:Matrix Metalloproteinase 3 / Q000235:genetics*; D011401:Promoter Regions, Genetic; D014158:Transcription, Genetic / Q000187:drug effects*; D014162:Transfection; D014407:Tumor Cells, Cultured
D007375:Interleukin-1; D003907:Dexamethasone; D019278:Matrix Metalloproteinase 3