The continuing debate: conservative or interventional therapy for unstable coronary artery disease.
A "look-and-act" approach, using a strategy of early intervention, and a "watchful waiting" approach, using medical therapy, are compared for the management of patients with unstable coronary artery disease (UCAD). Results from clinical trials are used to illustrate the advantages of antiplatelet and antithrombotic therapy and the problems associated with early intervention. Finally, a clinical management strategy for patients with UCAD is outlined. It is concluded that watchful waiting appears to be the most effective way of managing both patients and resources.
Hillis
W S
WS
Department of Medicine and Therapeutics, University of Glasgow, Gardiner Institute, United Kingdom.
D000789:Angina, Unstable / Q000188:drug therapy / Q000601:surgery / Q000628:therapy; D015906:Angioplasty, Balloon, Coronary; D003327:Coronary Disease / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D006801:Humans; D009203:Myocardial Infarction / Q000188:drug therapy / Q000601:surgery / Q000628:therapy; D016032:Randomized Controlled Trials as Topic; D015912:Thrombolytic Therapy; D013997:Time Factors; D016896:Treatment Outcome