[The possibilities of arifon in the combined therapy of unstable stenocardia in persons with arterial hypertension].
The authors studied the effect of arifon on vascular-platelet hemostasis in patients with unstable angina pectoris and hypertension. It was established that arifon addition to standard treatment leads to a decrease of platelet aggregation. A degree of spontaneous aggregation under arifon administration reduced to 30.9%, the rate of spontaneous aggregation decreased to 47.6% versus 13.3 and 24.6%, respectively, in arifon-untreated patients. Arifon promoted reduction of ADP-induced platelet aggregation to 26.9% (without arifon 6.5%); p < 0.01.
Iakovlev
V M
VM
Sokolov
G S
GS
D000328:Adult; D000368:Aged; D000789:Angina, Unstable / Q000097:blood / Q000188:drug therapy*; D002908:Chronic Disease; D004232:Diuretics / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D005082:Physical Exertion; D010974:Platelet Aggregation / Q000187:drug effects; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D013997:Time Factors; D014665:Vasodilator Agents / Q000627:therapeutic use*
D004232:Diuretics; D010975:Platelet Aggregation Inhibitors; D014665:Vasodilator Agents