title: Vascular complications of thoracic outlet syndrome.
abstract: Vascular complications of thoracic outlet syndrome are uncommon but may result in significant long-term disability. This report documents a retrospective review of 17 such patients. Ten patients presented with acute onset of upper extremity swelling and axillosubclavian vein thrombosis. One patient presented with chronic, intermittent arm swelling and subclavian vein stenosis. Three patients presented with acute symptoms of upper extremity emboli, and three presented with chronic arm claudication. Cervical ribs were discovered in four patients with arterial symptoms and in no patients with venous symptoms. All ten patients with acute venous thrombosis underwent successful thrombolysis, with venous stenosis uncovered in 8. Thrombolysis was also performed for two patients with arterial emboli. All 17 patients underwent surgical decompression of the thoracic outlet, 16 via a supraclavicular approach and one via a transaxillary approach. One subclavian arteriotomy with endarterectomy and one resection of a subclavian artery aneurysm were performed at the time of decompression. Repeat venography after decompression demonstrated persistent venous stenosis in one patient that was treated with balloon angioplasty and stenting. After a mean of 22 months' follow-up, 12 patients had no residual symptoms, and 5 had experienced significant improvement of symptoms. In conclusion, a combined approach of thrombolysis and surgical decompression of the thoracic outlet provides a salutary outcome in a majority of patients.
authors.affiliation: Department of Surgery, University of Southern California School of Medicine, Los Angeles 90033, USA.
authors.forename: D B
authors.initials: DB
authors.lastname: Hood
authors.forename: J
authors.initials: J
authors.lastname: Kuehne
authors.forename: A E
authors.initials: AE
authors.lastname: Yellin
authors.forename: F A
authors.initials: FA
authors.lastname: Weaver
mesh_terms: D000208:Acute Disease; D000328:Adult; D000368:Aged; D000783:Aneurysm / Q000601:surgery; D000800:Angioplasty, Balloon; D001132:Arm / Q000098:blood supply*; D001367:Axillary Vein / Q000473:pathology; D002573:Cervical Rib Syndrome / Q000150:complications; D002908:Chronic Disease; D003251:Constriction, Pathologic / Q000209:etiology; D004487:Edema / Q000209:etiology; D004617:Embolism / Q000188:drug therapy / Q000209:etiology; D004691:Endarterectomy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007383:Intermittent Claudication / Q000209:etiology; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D010690:Phlebography; D012189:Retrospective Studies; D015607:Stents; D013348:Subclavian Artery / Q000473:pathology / Q000601:surgery; D013350:Subclavian Vein / Q000473:pathology; D013901:Thoracic Outlet Syndrome / Q000150:complications* / Q000601:surgery; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000188:drug therapy / Q000209:etiology; D016896:Treatment Outcome