title: Comparison of patients with and without papillary muscle rupture during acute myocardial infarction.
abstract: Seventeen of 31 patients with papillary muscle rupture (PMR) were admitted with a >24-hour delay since onset of acute myocardial infarction (AMI) in contrast to 81 of 1,012 with AMI without cardiac rupture; in 8 of 11 patients with in-hospital PMR it was preceded by new anginal pain in 5 and/or by strenuous exercise in 4; mortality was higher in those with anterior PMR, previous infarction, or 3-vessel disease than in those without PMR. Thus, persistence of physical activity before or during hospitalization, as well as postinfarction ischemia/infarct extension, appear to be relevant triggers of PMR, whereas mortality is more often associated with existence of a previous infarction, 3-vessel disease, and/or anterior PMR.
authors.affiliation: Unitat Coronària, Servei de Cardiologia, Hospital General Vall d'Hebron, Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Figueras
authors.forename: F
authors.initials: F
authors.lastname: Calvo
authors.forename: J
authors.initials: J
authors.lastname: Cortadellas
authors.forename: J
authors.initials: J
authors.lastname: Soler-Soler
mesh_terms: D000368:Aged; D005260:Female; D006349:Heart Valve Diseases / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000209:etiology*; D009203:Myocardial Infarction / Q000150:complications*; D009336:Necrosis; D010210:Papillary Muscles / Q000473:pathology; D012422:Rupture, Spontaneous