[Thrombus in the right ventricle in an infant--a good result of thrombolytic therapy with recombinant tissue plasminogen activator].
In a 2 month-old infant presenting with the symptoms of cardio-respiratory failure in the course of staphylococcal septicaemia a thrombus in the right ventricle was detected in an echocardiographic examination. Scintigraphy of the lungs revealed of microthrombosis. Thrombolytic therapy with recombinant tissue plasminogen activator (Actylise) was started on the dose of 0.5 mg/kg/hour in 7-hour constant infusion. After 5 days of treatment the thrombus was completely dissolved. No complication were observed. Indicators of serum clothing remained normal during the treatment.
Aleszewicz-Baranowska
J
J
Klinik Kardiologu Instytutu, Pediatrii Akademii Medycznej w Gdańsku
Ratajczak
B
B
Wierzba
J
J
Irga
N
N
Filipowicz
J
J
D016470:Bacteremia / Q000150:complications; D006331:Heart Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D007223:Infant; D013203:Staphylococcal Infections / Q000150:complications; D015912:Thrombolytic Therapy; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*; D016896:Treatment Outcome; D014463:Ultrasonography
D010959:Tissue Plasminogen Activator