Effect of organotin compounds on trout hemoglobins.
The stability of trout hemoglobin was examined in the presence of some organotin compounds. Tributyltin chloride (TBTC) and triphenyltin chloride (TPTC) protect HbI most efficently from the oxidation. On the other hand, the same compounds accelerate the precipitation process in HbIV to a great extent. Parahydroxymercuribenzoate (PMB), an agent blocking free SH-groups of the protein, abolished the ability of TPTC to decrease the oxidation rate of HbI.
Santroni
A M
AM
Dipartimento di Biologia M.C.A., Università di Camerino, Camerino, Italy.
Fedeli
D
D
Gabbianelli
R
R
Zolese
G
G
Falcioni
G
G
D000818:Animals; D006454:Hemoglobins / Q000737:chemistry / Q000187:drug effects* / Q000378:metabolism; D009947:Organotin Compounds / Q000737:chemistry / Q000494:pharmacology*; D018384:Oxidative Stress; D014220:Trialkyltin Compounds / Q000737:chemistry / Q000494:pharmacology*; D014337:Trout / Q000097:blood*
D006454:Hemoglobins; D009947:Organotin Compounds; D014220:Trialkyltin Compounds; C011559:tributyltin; C012594:triphenyltin chloride