[Effect of low doses of radiation on the contractility of vascular smooth muscle at stretch].
The contractile reactions of the vascular smooth muscles at their stretch were studied in the isolated strips of v. porta of control rats and those, which had been born and exposed for 6 months to low intensity small dose radiation (Experimental Base in Chernobyl). The results obtained revealed the "mosaic" and significant disturbances (60% of cases) of the muscle contractile activity in the experimental animals. The myogenic mechanisms, which provide for the length-force dependence of the vessel's smooth muscles, were less effective in experimental vs. control animals. A major reason for the above changes may be the disturbances of the endothelium's function.
Tkachenko
M N
MN
Sagach
V F
VF
D000818:Animals; D066298:In Vitro Techniques; D009119:Muscle Contraction / Q000528:radiation effects*; D009131:Muscle, Smooth, Vascular / Q000502:physiology / Q000528:radiation effects*; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000503:physiopathology; D018788:Radioactive Hazard Release; D051381:Rats; D013314:Stress, Mechanical