title: Simple choristoma of the anterior segment containing brain tissue.
abstract: We report an unusual case of a simple choristoma of the anterior segment that contained only brain tissue. The clinical characteristics and findings of pathological examination of this unusual ocular malformation were reviewed. A newborn girl was seen with a fleshy, highly vascular cystic mass arising from the inferior limbus and extending across the cornea. On a computed tomographic scan, gross disruption of the anterior segment was present, with subluxation of the lens into the cyst. Excision of the abnormal tissue was followed by evisceration; polyglactin (Vicryl) ball implantation; patch graft of the globe; and, later, prosthetic fitting. Pathologic findings showed a choristomatous malformation, containing only mature brain tissue. To our knowledge, a choristoma in which the sole constituent is brain tissue has not previously been reported.
authors.affiliation: Department of Ophthalmology, British Columbia's Children's Hospital, Vancouver.
authors.forename: W E
authors.initials: WE
authors.lastname: Marshman
authors.forename: C J
authors.initials: CJ
authors.lastname: Lyons
authors.forename: D W
authors.initials: DW
authors.lastname: Young
authors.forename: V A
authors.initials: VA
authors.lastname: White
mesh_terms: D000869:Anterior Eye Segment / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D001921:Brain; D002828:Choristoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005128:Eye Diseases / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D017234:Eye Evisceration; D005260:Female; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism; D006801:Humans; D007124:Immunoenzyme Techniques; D007231:Infant, Newborn; D011098:Polyglactin 910; D019736:Prostheses and Implants; D014057:Tomography, X-Ray Computed
chemical_list: D005904:Glial Fibrillary Acidic Protein; D011098:Polyglactin 910