title: Bilateral anterior ischemic optic neuropathy as a presentation of Takayasu's disease.
abstract: Takayasu's disease is an arteritis with a predilection for the proximal branches of the aortic arch. Chronic retinal hypoxic changes and ischemic ocular inflammation, resulting from cervical vascular occlusion, have been described extensively. Anterior ischemic optic neuropathy has rarely been reported in this condition, and only in conjunction with other ophthalmic findings. Here we present the case of a patient who developed bilateral anterior ischemic optic neuropathy in the absence of other eye findings, and was subsequently found to have an aortic arch syndrome compatible with Takayasu's disease.
authors.affiliation: Department of Diagnostic Radiology and Nuclear Medicine, University of Western Ontario, London, Canada.
authors.forename: M H
authors.initials: MH
authors.lastname: Schmidt
authors.forename: A J
authors.initials: AJ
authors.lastname: Fox
authors.forename: D A
authors.initials: DA
authors.lastname: Nicolle
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001013:Aorta, Thoracic / Q000000981:diagnostic imaging; D001015:Aortic Arch Syndromes / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology; D001027:Aortography; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D008279:Magnetic Resonance Imaging; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D009898:Optic Disk / Q000098:blood supply* / Q000473:pathology; D018917:Optic Neuropathy, Ischemic / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D013625:Takayasu Arteritis / Q000150:complications* / Q000188:drug therapy
chemical_list: D000893:Anti-Inflammatory Agents; D008775:Methylprednisolone