DNA vaccines for parasitic infections.
There has been a tremendous explosion in the area of DNA vaccine research over the last 4 years, particularly in relation to antiviral vaccines. This report discusses the development and application of this new technology with regard to parasitic infections. Progress has been made towards the development of a vaccine against malaria, cryptosporidiosis, leishmaniasis, toxoplasmosis and schistosomiasis. In the future, nucleic acid vaccines will be a useful tool to help control these and other parasitic infections.
Kalinna
B H
BH
Molecular Parasitology Unit, Australian Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research, Bancroft Centre, Brisbane, Australia. berndK@qimr.edu.au
D000818:Animals; D000953:Antigens, Protozoan / Q000276:immunology*; D003457:Cryptosporidiosis / Q000276:immunology / Q000517:prevention & control; D005544:Forecasting; D007896:Leishmaniasis / Q000276:immunology / Q000517:prevention & control; D008288:Malaria / Q000276:immunology / Q000517:prevention & control; D051379:Mice; D010272:Parasitic Diseases / Q000276:immunology* / Q000517:prevention & control*; D010273:Parasitic Diseases, Animal / Q000276:immunology / Q000517:prevention & control; D012552:Schistosomiasis / Q000276:immunology / Q000517:prevention & control; D014123:Toxoplasmosis / Q000276:immunology / Q000517:prevention & control; D014124:Toxoplasmosis, Animal / Q000276:immunology / Q000517:prevention & control; D014611:Vaccination / Q000379:methods*; D019444:Vaccines, DNA / Q000627:therapeutic use*
D000953:Antigens, Protozoan; D019444:Vaccines, DNA