title: The emerging market for long-term nicotine maintenance.
abstract: In increasing numbers, Americans will seek to satisfy nicotine addictions through the use of novel nicotine-delivery products devoid of several of the poisons that make cigarettes so deadly. In the vanguard are tobacco industry devices that heat tobacco derivatives rather than burn tobacco, and pharmaceutical industry nicotine-replacement products, with nicotine gum and the patch now available over the counter. Ostensibly, these 2 industries have diametrically opposed objectives, the tobacco industry striving to sustain nicotine addictions, the pharmaceutical industry to end them. However, a series of technological, economic, political, regulatory, and social developments augurs a strange-bedfellows competition in which these industries will vie for shares of a new multibillion dollar long-term nicotine-maintenance market. Regulatory options range from encouraging competition to banning all nicotine-delivery devices. A more realistic approach discourages use of the most dangerous products, while making less hazardous products readily available to adults.
authors.affiliation: Department of Health Management and Policy, School of Public Health, University of Michigan, Ann Arbor 48109-2029, USA. kwarner@umich.edu
authors.forename: K E
authors.initials: KE
authors.lastname: Warner
authors.forename: J
authors.initials: J
authors.lastname: Slade
authors.forename: D T
authors.initials: DT
authors.lastname: Sweanor
mesh_terms: D000328:Adult; D003132:Commerce; D016503:Drug Delivery Systems; D004345:Drug Industry / Q000191:economics* / Q000331:legislation & jurisprudence; D005731:Ganglionic Stimulants / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D009538:Nicotine / Q000008:administration & dosage* / Q000627:therapeutic use; D011640:Public Policy; D019460:Tobacco Industry / Q000191:economics* / Q000331:legislation & jurisprudence; D014029:Tobacco Use Disorder / Q000191:economics / Q000517:prevention & control; D014481:United States
chemical_list: D005731:Ganglionic Stimulants; D009538:Nicotine