title: [Effect of occupational lead exposure on immunoglobulin concentration and cellular immune function in man].
abstract: The evaluation of immunological conditions of 14 workers occupationally exposed to lead and the comparison of these results with those of a non-exposed control group with similar age and sex were the aims of this study. It was determined the mean values of lead in blood. In exposed workers it was 46.9 micrograms/dl while in the control group it was 10.9 micrograms/dl. Levels of immunoglobulin decreasing while increasing lead concentration in blood were found in those exposed. It was also found a significant decrease in the formation for rosette in relation to the control group.
authors.affiliation: Sección de alergia e inmunología clínica, Instituto de Medicina del Trabajo, ciudad de La Habana, Cuba.
authors.forename: A
authors.initials: A
authors.lastname: Castillo Méndez
authors.forename: T
authors.initials: T
authors.lastname: Rodríguez Díaz
authors.forename: A
authors.initials: A
authors.lastname: León Lobeck
authors.forename: A J
authors.initials: AJ
authors.lastname: Gravalosa Cruz
mesh_terms: D000328:Adult; D000361:Agammaglobulinemia / Q000139:chemically induced*; D000917:Antibody Formation / Q000187:drug effects*; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects*; D007854:Lead / Q000009:adverse effects / Q000097:blood / Q000494:pharmacology*; D007855:Lead Poisoning / Q000276:immunology*; D008297:Male; D009784:Occupational Diseases / Q000139:chemically induced / Q000276:immunology*; D016273:Occupational Exposure; D012397:Rosette Formation
chemical_list: D007854:Lead