[Methods for calculating tolerance levels of lung irradiation as function of radiation dose and volume (modified LQ and TDF models)].
Modified mathematical TDF and LQ models that take into account the volumes of the irradiated lung were designed. An important radiological parameter, such as a single tolerance, has been inserted into the LQ model. Mathematical model parameters versus irradiated lung volume curves have been plotted. It is shown that the tolerance calculated using two models may greatly differ particularly for the small irradiated lung. Further collection and processing of radiological information are required for making a justified conclusion on the comparative efficiency of the above models used in radiological practice.
Klepper
L Ia
LIa
Makarova
G V
GV
D006801:Humans; D008168:Lung / Q000528:radiation effects*; D008175:Lung Neoplasms / Q000532:radiotherapy*; D008962:Models, Theoretical; D011836:Radiation Tolerance; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted