title: Simultaneous occurrence of papulonecrotic tuberculide and erythema induratum and the identification of Mycobacterium tuberculosis DNA by polymerase chain reaction.
abstract: The simultaneous occurrence of two tuberculides in one patient is rare. We report the case of a 32-year-old man presenting with both papulonecrotic tuberculide and erythema induratum. Mycobacterial DNA was identified from both skin lesions by polymerase chain reaction using formalin-fixed and paraffin-embedded tissues, suggesting that tuberculides are related to tuberculosis. New skin lesions developed after the patient discontinued his medication on his own initiative, 2 months after triple antituberculous therapy had been started. It is important to continue therapy for a prolonged period.
authors.affiliation: Department of Dermatology, Chang Gung Memorial Hospital, Taipel, Taiwan.
authors.forename: Y H
authors.initials: YH
authors.lastname: Chuang
authors.forename: T T
authors.initials: TT
authors.lastname: Kuo
authors.forename: C M
authors.initials: CM
authors.lastname: Wang
authors.forename: C N
authors.initials: CN
authors.lastname: Wang
authors.forename: W R
authors.initials: WR
authors.lastname: Wong
authors.forename: H L
authors.initials: HL
authors.lastname: Chan
mesh_terms: D000328:Adult; D004269:DNA, Bacterial / Q000032:analysis; D004891:Erythema Induratum / Q000150:complications / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D014382:Tuberculosis, Cutaneous / Q000150:complications / Q000382:microbiology / Q000473:pathology*
chemical_list: D004269:DNA, Bacterial