title: Stage IIIC ovarian leiomyosarcoma in a premenopausal woman with multiple recurrences: prolonged survival with surgical therapy.
abstract: A case of Stage IIIC primary ovarian leiomyosarcoma in a premenopausal woman with multiple recurrences alive and well 7 years after diagnosis is presented. In addition to the typical light microscopic, immunohistochemical, and electron microscopic features of ovarian leiomyosarcoma, the tumor was progesterone receptor positive. This is 28th report of primary ovarian leiomyosarcoma and the first report of progesterone receptor in this tumor. This is the longest reported survival in a woman with this disease.
authors.affiliation: Department of Obstetrics and Gynecology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, Iowa 52242, USA.
authors.forename: C C
authors.initials: CC
authors.lastname: Rasmussen
authors.forename: J S
authors.initials: JS
authors.lastname: Skilling
authors.forename: J I
authors.initials: JI
authors.lastname: Sorosky
authors.forename: D J
authors.initials: DJ
authors.lastname: Lager
authors.forename: R E
authors.initials: RE
authors.lastname: Buller
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000473:pathology / Q000601:surgery; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery; D017697:Premenopause