title: Transient leukaemia cutis in chronic lymphocytic leukaemia.
abstract: Leukaemia cutis arises due to cutaneous infiltration of neoplastic leukocytes or their precursors. Recent evidence suggests that this sign does not necessarily herald a poor prognosis. We describe a 72-year-old woman with B-cell chronic lymphatic leukaemia (CLL) who developed a papular eruption on her breast at the site of a recent herpetic eruption. Histology and immunostaining showed a dense dermal B-cell infiltrate in keeping with leukaemia cutis. The papules cleared in 6 months without treatment, leaving atrophic scars. The histological features and possible aetiological mechanisms of post-herpetic papular eruptions in CLL are reviewed.
authors.affiliation: Department of Dermatology, Amersham Hospital, Bucks, UK.
authors.forename: S H
authors.initials: SH
authors.lastname: Wakelin
authors.forename: E
authors.initials: E
authors.lastname: Young
authors.forename: S
authors.initials: S
authors.lastname: Kelly
authors.forename: M
authors.initials: M
authors.lastname: Turner
mesh_terms: D000368:Aged; D005260:Female; D006562:Herpes Zoster / Q000150:complications; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications / Q000473:pathology*; D017254:Leukemic Infiltration; D012867:Skin / Q000473:pathology*