title: Modified intraparietal vagotomy in the treatment of perforated duodenal ulcer.
abstract: OBJECTIVE
  The purpose of this study was to introduce modified intraparietal vagotomy as a safe procedure and a method of choice in the treatment of perforated duodenal ulcers.
  
  
  METHODS
  Eighty-six patients with perforated duodenal ulcers underwent oversewing of the perforated ulcer and modified intraparietal selective vagotomy. The site of perforation was sewn over and an abdominal cavity lavage was performed. The posterior vagal nerve was resected, and a modified intraparietal anterior vagotomy was performed. During the postoperative period, after twenty days, six months and one year, respectively, we analyzed the following data: body weight, signs of gastroesophageal reflux, subjective discomfort, early postoperative complications, gastroduodenoscopic findings, basal acid output (BAO), and maximal acid output stimulated by pentagastrin (PAO).
  
  
  RESULTS
  There was no mortality in our group, the post-operative morbidity was insignificant, and the duration of operation was shorter in comparison to other vagotomy methods. BAO and PAO values were similar to those in the literature when proximal selective vagotomy (PSV) was performed. There were no cases of duodenogastric or gastroesophageal reflux nor re-occurrence of ulcer disease, as confirmed by gastroduodenoscopy. According to the modified Visick's criteria, 94% of the patients followed-up were classified as group 1.
  
  
  CONCLUSIONS
  We consider the modified intraparietal vagotomy to be the method of choice in the treatment of perforated duodenal ulcers because of the simple surgical technique involved, the shorter duration of surgery, and the avoidance of standard PSV complications. The surgery can be performed even by a less experienced surgeon, independently of the patient's age and condition. This modification is suitable for laparoscopic surgery.
authors.affiliation: Clinical Hospital Split, Department of Abdominal Surgery Krizine, Split, Republic of Croatia.
authors.forename: N
authors.initials: N
authors.lastname: Druzijanic
authors.forename: J
authors.initials: J
authors.lastname: Juricic
authors.forename: A
authors.initials: A
authors.lastname: Bakovic
authors.forename: D
authors.initials: D
authors.lastname: Kraljevic
mesh_terms: D000328:Adult; D004381:Duodenal Ulcer / Q000150:complications / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010439:Peptic Ulcer Perforation / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D014629:Vagotomy, Proximal Gastric / Q000379:methods*