Twists and turns of the nucleosome: tails without ends.
The high-resolution structure of a nucleosome core particle gives us our first detailed look at the primary level of eukaryotic DNA organization. The structure reveals the nature of histone-DNA contacts and provides some surprises regarding the histone tails and their possible involvement in higher levels of chromatin organization.
Dutnall
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Department of Biochemistry, University of Utah School of Medicine, Salt Lake City 84132, USA.
Ramakrishnan
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D000818:Animals; D001483:Base Sequence; D018360:Crystallography, X-Ray; D004247:DNA / Q000737:chemistry; D005057:Eukaryotic Cells; D006657:Histones / Q000737:chemistry*; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009690:Nucleic Acid Conformation; D009707:Nucleosomes / Q000737:chemistry*; D011487:Protein Conformation
D006657:Histones; D009707:Nucleosomes; D004247:DNA