title: Massive osteolysis of the skull and upper cervical spine. Case report and review of the literature.
abstract: Massive osteolysis is a type of idiopathic osteolysis in which there is spontaneous onset of bone resorption. Almost any bone in the body can be affected. The authors present the case of a 62-year-old man diagnosed with massive osteolysis of the occipital bone and the upper two cervical vertebrae. Despite extensive pneumocephalus, no neurological sign or spinal instability was evident. In this case 4000 cGy of radiation in 200-cGy fractions was administered to the diseased area while the patient was kept in a Miami-J collar. At the 2-year follow-up examination, arrest of the disease process and new bone formation was evident on radiographic studies.
authors.affiliation: Department of Neurosurgery, West Virginia University, Morgantown 26506, USA.
authors.forename: H
authors.initials: H
authors.lastname: Khosrovi
authors.forename: O
authors.initials: O
authors.lastname: Ortiz
authors.forename: H H
authors.initials: HH
authors.lastname: Kaufman
authors.forename: S S
authors.initials: SS
authors.lastname: Schochet
authors.forename: G N
authors.initials: GN
authors.lastname: Reddy
authors.forename: D
authors.initials: D
authors.lastname: Simmons
mesh_terms: D002574:Cervical Vertebrae; D006801:Humans; D008297:Male; D008875:Middle Aged; D010014:Osteolysis / Q000145:classification / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D011379:Prognosis; D012886:Skull