Gadolinium-enhanced magnetic resonance angiography of the pelvis in patients with erectile impotence.
This study evaluated the potential of contrast-enhanced digital-subtraction magnetic resonance angiography (CE-DS-MRA) for noninvasive angiographic delineation of the arterial supply of the penis in patients with erectile dysfunction. After induction of an erection with prostaglandin E, a three-dimensional fast imaging with steady-state precision (FISP) sequence with TE of 1.8-2 milliseconds, TR of 4.4-5 milliseconds, and flip angle of 40 degrees-60 degrees was used to obtain high-resolution angiograms of the pelvis and penis during the injection of gadolinium diethylenetriaminepentaacetic acid (Gd-DTPA) 0.3 mmol/kg body weight, within 30-50 seconds. DS maximum intensity projections (MIPs) and multiplanar reconstructions (MPRs) were compared with clinical work-up and directional Doppler ultrasound in 11 patients. In all 11 patients (100%), the arterial supply of the penis could be delineated from the aortic bifurcation via the iliac and internal pudendal arteries to the dorsal and deep penile arteries. Of the 22 internal pudendal arteries, 6 (27%) were occluded on CE-DS-MRA and 5 (23%) had stenoses, of which 4 (18%) were greater than 50%. In 7 patients (64%) good correlation between CE-DS-MRA and clinical findings and/or Doppler ultrasound was found; in 2 patients (18%), the correlation was moderate, and in 2 patients (18%) results were discrepant. In 6 patients (55%), MRA provided additional information to the clinical and Doppler ultrasound work-up. CE-DS-MRA can delineate small vessels such as the internal pudendal and penile arteries and thus has the potential to become a noninvasive angiography method in the work-up of erectile impotence.
Stehling
M K
MK
Radiologic Institute, Munich, Germany.
Liu
L
L
Laub
G
G
Fleischmann
K
K
Rohde
U
U
D001158:Arteries / Q000473:pathology; D007172:Erectile Dysfunction / Q000175:diagnosis*; D005069:Evaluation Studies as Topic; D005682:Gadolinium; D006801:Humans; D007083:Iliac Artery / Q000473:pathology; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D010388:Pelvis / Q000000981:diagnostic imaging / Q000473:pathology*; D010410:Penile Erection / Q000502:physiology*; D010413:Penis / Q000098:blood supply / Q000000981:diagnostic imaging; D011856:Radiographic Image Enhancement; D011877:Radionuclide Imaging; D018608:Ultrasonography, Doppler / Q000379:methods
D005682:Gadolinium