title: Switching gears during T-cell maturation: RANTES and late transcription.
abstract: Although much is understood about the induction of genes expressed early (within 24 h) after T-cell activation, little is known about the regulation of expression of genes expressed 'late' (three or more days) post-stimulation. A better understanding of transcriptional regulation at this important stage of T-cell maturation may yield new insights into T-cell development and new immunotherapeutic targets.
authors.affiliation: Division of Immunology, University of California, Berkeley 94720-3200, USA.
authors.forename: B D
authors.initials: BD
authors.lastname: Ortiz
authors.forename: P J
authors.initials: PJ
authors.lastname: Nelson
authors.forename: A M
authors.initials: AM
authors.lastname: Krensky
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D018946:Chemokine CCL5 / Q000235:genetics*; D006801:Humans; D007167:Immunotherapy; D008213:Lymphocyte Activation / Q000235:genetics; D011401:Promoter Regions, Genetic; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology* / Q000378:metabolism; D013997:Time Factors; D014157:Transcription Factors / Q000378:metabolism; D014158:Transcription, Genetic
chemical_list: D018946:Chemokine CCL5; D014157:Transcription Factors