title: [Combined treatment of stomach neoplasms].
abstract: The results of treatment of 394 patients with gastric cancer were analysed to compare the effectiveness of surgical and two variants of combined treatment (preoperative irradiation with intensive-concentrated IKK method and dynamic DFD dose-fractioning). The advantages of combined treatment over surgical treatment are demonstrated. The 3-year survival in the combined treatment is 70.2%, in surgical treatment 34.5 +/- 6.2%. The advantages of SDF preoperative irradiation over IKK irradiation are revealed, that is proved by the increase of the 3-year survival rate (76 vs. 56.7%), and decrease in the rate of recurrence from 50 to 27.3%. The addition of metronidazol leads to increase of anticancer effectiveness, that is proved with the examination of tumor pathomorphosis and the rates of survival.
authors.affiliation: Scientific-Research Oncologic Institute , Moscow.
authors.forename: V I
authors.initials: VI
authors.lastname: Chissov
authors.forename: S L
authors.initials: SL
authors.lastname: Dar'ialova
authors.forename: L A
authors.initials: LA
authors.lastname: Vashakmadze
authors.forename: V S
authors.initials: VS
authors.lastname: Zuí
authors.forename: T A
authors.initials: TA
authors.lastname: Belous
mesh_terms: D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D004307:Dose-Response Relationship, Radiation; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery*; D015996:Survival Rate; D016896:Treatment Outcome