Blood pressure peaks correlated with plasma fibronectin levels and microalbuminuria in hypertensive pregnancies.
A group of 32 selected hypertensive pregnant women under antihypertensive therapy, with biochemical parameters, functional parameters, plasma fibronectin levels (PLF), microalbuminuria (MA) levels and continuous 24 h blood pressure monitoring, were followed monthly until delivery and during puerperium. Also possible biochemical and clinical markers and the predictive value in the complications during PIH were attempted to be identified. There was a statistical correlation between systolic pressure peaks associated with high levels of PLF and MA in hypertensive pregnant women who may have a higher risk of pregnancy or cardiovascular complications. Continuous 24 h blood pressure monitoring in hypertensive pregnancies was found to be helpful in identifying the highest risk patients especially by reading the night peak percentages.
Panella
M
M
1a Clinica Ostetrica e Ginecologia, Università di Catania, Italy.
Rocchi
M C
MC
Landolina
C
C
Rizzo
S
S
Viglianisi
G
G
Noto
R
R
Longhitano
A
A
Garozzo
G
G
D000293:Adolescent; D000328:Adult; D000419:Albuminuria / Q000503:physiopathology*; D001794:Blood Pressure; D002585:Cesarean Section; D003971:Diastole; D005260:Female; D005353:Fibronectins / Q000097:blood*; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008875:Middle Aged; D011225:Pre-Eclampsia / Q000503:physiopathology; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000503:physiopathology*; D013599:Systole
D005353:Fibronectins