Acute pancreatitis secondary to ifosfamide.
Acute pancreatitis in cancer patients can be secondary to the malignant process itself. It is also a rare complication of antineoplastic agent administration. Ifosfamide is an effective drug in the treatment of several tumors and has known neurologic, renal, and hematologic toxicities. There is only one recent report in the literature of pancreatitis associated with ifosfamide. We report a case of a 65-year-old woman with small cell bronchogenic carcinoma without pancreatic metastases who developed acute pancreatitis after ifosfamide administration.
Gerson
R
R
Unidad de Quimioterapia, Hospital General de Mexico, Mexico City, Mexico.
Serrano
A
A
Villalobos
A
A
Sternbach
G L
GL
Varon
J
J
D000208:Acute Disease; D000368:Aged; D018906:Antineoplastic Agents, Alkylating / Q000009:adverse effects*; D018288:Carcinoma, Small Cell / Q000188:drug therapy; D005260:Female; D006801:Humans; D007069:Ifosfamide / Q000009:adverse effects*; D008175:Lung Neoplasms / Q000188:drug therapy; D010195:Pancreatitis / Q000139:chemically induced*
D018906:Antineoplastic Agents, Alkylating; D007069:Ifosfamide