title: Marked dilutional acidosis complicating management of right ventricular myocardial infarction.
abstract: Dilutional acidosis is a poorly recognized cause of metabolic acidosis. Indeed, the prevailing view has been that even massive expansion of the extracellular fluid volume with non-bicarbonate-containing solutions would not lead to clinically significant hypobicarbonatemia. We describe the development of marked dilutional acidosis as a complication of management of right ventricular myocardial infarction. The pathogenesis, clinical significance, prevention, and treatment of the entity are discussed.
authors.affiliation: Department of Medicine, Tufts University School of Medicine, New England Medical Center, Boston, MA 02111, USA.
authors.forename: B L
authors.initials: BL
authors.lastname: Jaber
authors.forename: N E
authors.initials: NE
authors.lastname: Madias
mesh_terms: D000138:Acidosis / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D000368:Aged; D001639:Bicarbonates / Q000097:blood; D005110:Extracellular Space; D005440:Fluid Therapy / Q000009:adverse effects*; D006438:Hemodilution / Q000009:adverse effects; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000150:complications / Q000628:therapy*; D013997:Time Factors
chemical_list: D001639:Bicarbonates