Serum S-100 has prognostic significance in malignant melanoma.
BACKGROUND
Pretreatment serum values of S-100 and NSE were compared in patients with malignant melanoma.


METHODS
Pretreatment serum levels of patients with malignant melanoma were analysed for stage of disease and survival.


RESULTS
S-100 pretreatment serum values seem highly specific, but have low sensitivity.


CONCLUSIONS
Further evaluation is needed with an assay with improved sensitivity.
Bonfrer
J M
JM
Department of Clinical Chemistry, The Netherlands Cancer Institute (Antoni van Leeuwenhoek Huis), Amsterdam, The Netherlands.
Korse
C M
CM
Israels
S P
SP
D006801:Humans; D008545:Melanoma / Q000097:blood*; D010751:Phosphopyruvate Hydratase / Q000097:blood; D011379:Prognosis; D009418:S100 Proteins / Q000097:blood*; D012680:Sensitivity and Specificity
D009418:S100 Proteins; D010751:Phosphopyruvate Hydratase