Disseminated bacillus Calmette-Guerin infection in an HIV-infected child: a case with cutaneous lesions.
A boy born to a mother with unknown HIV infection was immunized with BCG in his first month of life. Seven months later axillary adenopathy developed. At the age of 10 months, 2 months after HIV infection had been diagnosed, papular skin lesions appeared all over his body. Mycobacterium bovis, BCG strain, was cultured from a lymph node and blood. Ziehl-Neelsen stain of a skin biopsy specimen showed histiocytes loaded with numerous acid-fast bacilli. The patient died 10 days later, before the infection was confirmed. This is the first reported case of disseminated BCG infection in an HIV-infected child presenting with cutaneous lesions.
Ratón
J A
JA
Department of Dermatology, Cruces Hospital, Bilbao, Spain.
Pocheville
I
I
Vicente
J M
JM
González
R
R
Bilbao
I
I
Gutierrez
C
C
Díaz-Pérez
J L
JL
D001365:Axilla; D001500:BCG Vaccine / Q000009:adverse effects*; D002648:Child; D006679:HIV Seropositivity; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000382:microbiology; D008297:Male; D009164:Mycobacterium Infections / Q000382:microbiology*; D009163:Mycobacterium bovis / Q000302:isolation & purification*; D012871:Skin Diseases / Q000382:microbiology* / Q000473:pathology
D001500:BCG Vaccine