A simple method to calculate P50 from a single blood sample.
Hill's equation relating oxygen tension, saturation and P50 is used as the basis for a simple method to calculate P50 from a single blood sample. The effects of errors of measurement in oxygen tension and saturation are considered using the technique of sensitivity analysis. The method is illustrated using data published by Severinghaus.
Doyle
D J
DJ
Department of Anaesthesia, Toronto Hospital, Ontario, Canada.
D001784:Blood Gas Analysis; D006454:Hemoglobins / Q000032:analysis* / Q000378:metabolism; D006801:Humans; D008432:Mathematical Computing; D010100:Oxygen / Q000097:blood*; D010313:Partial Pressure
D006454:Hemoglobins; D010100:Oxygen