title: Staphylococcal necrotizing fasciitis in the mammary region in childhood: a report of five cases.
abstract: OBJECTIVE
  Necrotizing fasciitis is a highly lethal soft tissue infection rarely reported in childhood. The initiating site is usually a local trauma or a surgical wound. We observed five cases of necrotizing fasciitis the initiating site for which was the mammary region and discuss their management.
  
  
  METHODS
  We describe these five patients and review the clinical characteristics of their presentation.
  
  
  RESULTS
  Staphylococcal necrotizing fasciitis was observed in the mammary region in all five cases. Four children were newborn infants with a mammitis preceding the onset of necrotizing fasciitis. Surgical débridement was done only after the fourth day from onset of illness. All children were discharged in good condition after 1 month. Two have been followed until puberty, with destruction of the mammary gland in one case and good development in the other one.
  
  
  CONCLUSIONS
  Mammitis may be the initiating event for necrotizing fasciitis in neonates. Necrotizing fasciitis is a life-threatening disease; patients require early intensive care, parenteral antibiotic therapy, and surgical débridement. In a few instances surgery can be carefully delayed until the necrotic area is more delineated if the condition is diagnosed early during disease evolution and appropriate treatment is instituted in intensive care units.
authors.affiliation: Department of Dermatology, Hôpital Necker Enfants-Malades, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Bodemer
authors.forename: A
authors.initials: A
authors.lastname: Panhans
authors.forename: B
authors.initials: B
authors.lastname: Chretien-Marquet
authors.forename: M
authors.initials: M
authors.lastname: Cloup
authors.forename: D
authors.initials: D
authors.lastname: Pellerin
authors.forename: Y
authors.initials: Y
authors.lastname: de Prost
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002675:Child, Preschool; D003131:Combined Modality Therapy; D003646:Debridement; D019115:Fasciitis, Necrotizing / Q000382:microbiology* / Q000628:therapy; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008413:Mastitis / Q000382:microbiology* / Q000628:therapy; D008826:Microbial Sensitivity Tests; D013203:Staphylococcal Infections / Q000382:microbiology* / Q000628:therapy; D013211:Staphylococcus aureus
chemical_list: D000900:Anti-Bacterial Agents