An in vivo model for functional MRI in cat visual cortex.
A protocol is described for obtaining functional magnetic resonance images in anesthetized cat brain based on the blood oxygenation level dependent (BOLD) contrast mechanism. A visual stimulus was used, which consisted of a high-contrast drifting grating, whose speed and spatial frequency was optimized for cat area 18 (V2). Experiments were conducted at 4.7 Tesla using a gradient echo EPI sequence with a 29-ms echo time, yielding signal changes of between 0.7% and 2% in area 18.
Jezzard
P
P
Unit on MRI Physics, LBC, NIMH, NIH, Bethesda, MD 20892-1366, USA.
Rauschecker
J P
JP
Malonek
D
D
D000818:Animals; D002415:Cats; D017352:Echo-Planar Imaging; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010100:Oxygen / Q000097:blood; D014793:Visual Cortex / Q000033:anatomy & histology* / Q000502:physiology
D010100:Oxygen