title: Structural and sequence-based classification of glycoside hydrolases.
abstract: The diversity of oligo- and polysaccharides provides an abundance of biological roles for these carbohydrates. The enzymes hydrolysing these compounds, the glycoside hydrolases, therefore mediate a wealth of biological functions. Glycoside hydrolases fall into a number of sequence-based families. The recent analysis of these families, coupled with the burgeoning number of 3D structures, provides a detailed insight into the structure, function and catalytic mechanism of these enzymes.
authors.affiliation: Centre de Recherches sur les Macromolécules Végétales, CNRS, Joseph Fourier Université, Grenoble, France. bernie@cermav.grenet.fr
authors.forename: B
authors.initials: B
authors.lastname: Henrissat
authors.forename: G
authors.initials: G
authors.lastname: Davies
mesh_terms: D000595:Amino Acid Sequence; D002236:Carbohydrate Conformation; D006026:Glycoside Hydrolases / Q000737:chemistry* / Q000145:classification* / Q000378:metabolism; D008969:Molecular Sequence Data; D011487:Protein Conformation; D017386:Sequence Homology, Amino Acid; D013379:Substrate Specificity
chemical_list: D006026:Glycoside Hydrolases