Invasive pulmonary aspergillosis with cerebromeningeal involvement after short-term intravenous corticosteroid therapy in a patient with asthma.
The present case report describes a case of invasive pulmonary aspergillosis with cerebromeningeal invasion in an asthmatic non-immunocompromised patient. This fatal complication occurred despite early anti-fungal antibiotherapy after a 2-week course of intravenous corticosteroid therapy for treatment of an exacerbated asthma. Diagnostic and therapeutic procedures are discussed.
Monlun
E
E
Service de Réanimation Médicale, Hôpitaux Universitaires de Strasbourg, France.
de Blay
F
F
Berton
C
C
Gasser
B
B
Jaeger
A
A
Pauli
G
G
D000368:Aged; D001228:Aspergillosis / Q000175:diagnosis / Q000209:etiology*; D001249:Asthma / Q000188:drug therapy*; D001927:Brain Diseases / Q000382:microbiology; D017809:Fatal Outcome; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000209:etiology*; D008775:Methylprednisolone / Q000009:adverse effects*
D005938:Glucocorticoids; D008775:Methylprednisolone