title: Priapism in a patient with protein C deficiency.
abstract: We present the case of a patient with classical protein C deficiency presenting with acute priapism during warfarinization for thrombophlebitis. Priapism is a well-recognized complication of a number of conditions including sickle cell disease and haematological malignancies, but to our knowledge it has not previously been reported in association with protein C deficiency. This case highlights the potential dangers of initiating oral anticoagulant therapy using conventional loading dose regimens in patients with protein C deficiency.
authors.affiliation: CRC Institute of Cancer Studies, University of Birmingham, Medical School, UK.
authors.forename: S
authors.initials: S
authors.lastname: Daryanani
authors.forename: J T
authors.initials: JT
authors.lastname: Wilde
mesh_terms: D000208:Acute Disease; D000328:Adult; D000925:Anticoagulants / Q000009:adverse effects*; D006801:Humans; D008297:Male; D011317:Priapism / Q000139:chemically induced*; D020151:Protein C Deficiency; D014859:Warfarin / Q000009:adverse effects*
chemical_list: D000925:Anticoagulants; D014859:Warfarin