Hydranencephaly with renal dysgenesis: a coincidental finding? Case report with review of the literature.
We present the case of a female fetus aborted in the 20th week of gestation due to severely dysplastic kidneys, anhydramnios and hydranencephalus. The combination of these malformations is extremely rare, resulting in only 4 cases described so far. Our case is the first ever presented in a female showing polycystic-dysplastic kidneys. Multiple multinucleated neurons were a remarkable finding in the remnants of the brain. The possibility of an underlying genetic disorder is discussed, together with a brief review of the literature to date.
Gschwendtner
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Department of Pathology, University of Innsbruck, Austria.
Mairinger
T
T
Soelder
E
E
Alge
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Kreczy
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A
D000028:Abortion, Induced; D000328:Adult; D005260:Female; D005865:Gestational Age; D006801:Humans; D006832:Hydranencephaly / Q000150:complications* / Q000175:diagnosis; D007668:Kidney / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D007690:Polycystic Kidney Diseases / Q000150:complications* / Q000151:congenital / Q000175:diagnosis; D011247:Pregnancy; D016216:Ultrasonography, Prenatal