[Pulmonary edema associated with the ingestion of hydrochlorothiazide].
Hydrochlorotiazide may cause pulmonary dema. We report two female patients aged 58 and 69 years old, who after the ingestion of this diuretic, were admitted to an intensive care unit with fever, digestive symptoms, severe dyspnea, hypotension and a hemodynamic pattern resembling hypovolemia. Both had a good response to volume repletion and vasoactive drugs. Despite the severity of the clinical picture, they had a full and fast recovery. This type of reaction to hydrochlorotiazide is probably idiosyncratic and must be considered in the differential diagnosis of pulmonary edema.
Marín
P
P
Unidad de Cuidados Intensivos, Servicio de Medicina, Hospital Regional de Talca.
D000208:Acute Disease; D000368:Aged; D000959:Antihypertensive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000009:adverse effects* / Q000627:therapeutic use; D006973:Hypertension / Q000188:drug therapy; D008875:Middle Aged; D011654:Pulmonary Edema / Q000139:chemically induced* / Q000175:diagnosis
D000959:Antihypertensive Agents; D006852:Hydrochlorothiazide