Sulphasalazine therapy in chronic uveitis of children with chronic arthritis.
Four children with chronic arthritis (3 juvenile rheumatoid arthritis and 1 juvenile ankylosing spondylitis) and poorly controlled chronic uveitis, were given sulphasalazine (SASP) therapy for a mean period of 3.3 years. Three patients showed an excellent response, as evidenced by a reduction of inflammatory cells in the anterior chamber of the eyes and improvement of visual acuity. The response occurred after a mean of 7.7 weeks. These data suggested SASP therapy may have a role in the treatment of chronic anterior uveitis in children with chronic arthritis.
Huang
J L
JL
Department of Pediatrics, Chang Gung Children's Hospital and Chang Gung Medical College, Taoyuan, Taiwan.
Hung
I J
IJ
Hsieh
K H
KH
D000293:Adolescent; D000328:Adult; D018501:Antirheumatic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001171:Arthritis, Juvenile / Q000150:complications* / Q000188:drug therapy; D002648:Child; D002908:Chronic Disease; D005260:Female; D006801:Humans; D015863:Iridocyclitis / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D012189:Retrospective Studies; D013167:Spondylitis, Ankylosing / Q000150:complications* / Q000188:drug therapy; D012460:Sulfasalazine / Q000008:administration & dosage / Q000627:therapeutic use*
D018501:Antirheumatic Agents; D012460:Sulfasalazine