title: Is crusted (Norwegian) scabies a marker of adult T cell leukemia/lymphoma in human T lymphotropic virus type I-seropositive patients?
abstract: Human T cell lymphotropic virus type I (HTLV-I)-induced immunosuppression has been suggested to explain the occurrence of crusted scabies in HTLV-I-infected patients. HTLV-I is the etiologic agent of adult T cell leukemia/lymphoma (ATL). Crusted scabies diagnosed in 6 HTLV-I-seropositive patients was studied to look for an association with ATL. Four of the 6 either had concomitant ATL when crusted scabies was diagnosed or developed ATL a few months later. These findings suggest that the occurrence of crusted scabies in patients seropositive for HTLV-I could represent a sign of marked immunosuppression related to ATL.
authors.affiliation: Department of Dermatology, Hôpital Général de Cayenne, French Guiana.
authors.forename: P
authors.initials: P
authors.lastname: del Giudice
authors.forename: D
authors.initials: D
authors.lastname: Sainte Marie
authors.forename: Y
authors.initials: Y
authors.lastname: Gérard
authors.forename: P
authors.initials: P
authors.lastname: Couppié
authors.forename: R
authors.initials: R
authors.lastname: Pradinaud
mesh_terms: D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000032:analysis*; D003937:Diagnosis, Differential; D005260:Female; D015481:HTLV-I Antibodies / Q000032:analysis; D006801:Humans; D016867:Immunocompromised Host; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000175:diagnosis* / Q000276:immunology; D008297:Male; D012532:Scabies / Q000175:diagnosis* / Q000276:immunology
chemical_list: D015415:Biomarkers; D015481:HTLV-I Antibodies