[In vitro susceptibility to antifungal agents of Candida strains isolated from patients with various diseases of the respiratory tract].
The aim of the study was the estimation of in vitro susceptibility to antifungal agents of yeast isolated from sputum of 70 respiratory diseases patients using the disc-diffusion method-antimycogram. The following agents were tested: amphotericin B, 5-fluorocytosine, nystatin, ketoconazole, fluconazole. Only Candida strains were isolated from sputum, 82% of them were Candida albicans. We noted differences in susceptibility to antimycotics of Candida strains. The best antimycotic in vitro was 5-fluorocytosine. 54% of isolated Candida strains were resistant to 1 or more antimycotics.
Batura-Gabryel
H
H
Kliniki Pneumonologii Instytutu Chorób Wewnetrznych A. M. w Poznaniu.
Wieczorek
U
U
Mlynarczyk
W
W
D000328:Adult; D000368:Aged; D000666:Amphotericin B / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000009:adverse effects; D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects*; D002177:Candidiasis / Q000139:chemically induced; D015725:Fluconazole / Q000494:pharmacology; D005437:Flucytosine / Q000494:pharmacology; D006801:Humans; D007654:Ketoconazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009761:Nystatin / Q000494:pharmacology; D012141:Respiratory Tract Infections / Q000150:complications / Q000188:drug therapy / Q000382:microbiology*; D013045:Species Specificity; D013183:Sputum / Q000382:microbiology*
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D009761:Nystatin; D000666:Amphotericin B; D015725:Fluconazole; D005437:Flucytosine; D007654:Ketoconazole