title: [Contrast media-associated nephropathy--pathogenesis and prevention].
abstract: Contrast media-associated nephrotoxicity continues to be a relevant cause of acute renal failure, especially in patients with pre-existing renal insufficiency. Alterations in renal hemodynamics and direct tubular toxicity by contrast media are the primary factors believed to be responsible for contrast media-associated nephrotoxicity. We review recent insights into the pathogenesis of this complication and summarize prophylactic strategies focussing on hydration, vasoactive pharmacological agents, and prophylactic hemodialysis'.
authors.affiliation: Abteilung Innere Medizin III, Universität Tübingen.
authors.forename: C M
authors.initials: CM
authors.lastname: Erley
authors.forename: S H
authors.initials: SH
authors.lastname: Duda
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000517:prevention & control; D003287:Contrast Media / Q000009:adverse effects*; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006801:Humans; D007668:Kidney / Q000098:blood supply; D007677:Kidney Function Tests; D007684:Kidney Tubules / Q000187:drug effects; D012039:Regional Blood Flow / Q000187:drug effects; D006435:Renal Dialysis; D012307:Risk Factors; D013806:Theophylline / Q000008:administration & dosage; D014665:Vasodilator Agents / Q000008:administration & dosage
chemical_list: D003287:Contrast Media; D014665:Vasodilator Agents; D013806:Theophylline