Autosomal recessive inheritance of erythrokeratoderma variabilis.
Erythrokeratoderma variabilis is a rare genodermatosis conventionally regarded as autosomal dominant in inheritance. We describe the clinical features and light and electron microscopic findings in two affected siblings born to unaffected parents and suggest an autosomal recessive mode of inheritance in this family. We also briefly review the literature on this disorder.
Armstrong
D K
DK
Department of Dermatology, Belfast City Hospital, Northern Ireland.
Hutchinson
T H
TH
Walsh
M Y
MY
McMillan
J C
JC
D004890:Erythema / Q000150:complications* / Q000235:genetics* / Q000473:pathology; D005808:Genes, Recessive; D006801:Humans; D007223:Infant; D007642:Keratosis / Q000150:complications* / Q000235:genetics* / Q000473:pathology; D008297:Male; D012867:Skin / Q000473:pathology