New steroidal alkaloids from Buxus longifolia.
Four new steroidal alkaloids, (+)-cyclovirobuxeine F (1), N-benzoyl-O-acetylbuxalongifoline (2), buxasamarine (3), and (+)-cyclobuxamidine (4), along with two known steroidal bases, 16 alpha-acetoxybuxabenzamidienine (5) and trans-cyclosuffrobuxinine (6), were isolated from the leaves of Buxus longifolia. The alkaloids 1-4 showed significant antibacterial activity.
Atta-ur-Rahman
H.E.J. Research Institute of Chemistry, University of Karachi, Pakistan. att@hejfirst%uunet.uu.net
Noor-e-ain
F
F
Choudhary
M I
MI
Parveen
Z
Z
Türköz
S
S
Sener
B
B
D000470:Alkaloids / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D002240:Carbohydrate Sequence; D002855:Chromatography, Thin Layer; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D018515:Plant Leaves / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*
D000470:Alkaloids; D000900:Anti-Bacterial Agents