title: Structure of a conserved RNA component of the peptidyl transferase centre.
abstract: The structure of a conserved hairpin loop involved in peptidyl-tRNA recognition by 50S ribosomal subunits has been solved by NMR. The loop is closed by a novel G-C base pair and presents guanine residues for RNA recognition.
authors.forename: E V
authors.initials: EV
authors.lastname: Puglisi
authors.forename: R
authors.initials: R
authors.lastname: Green
authors.forename: H F
authors.initials: HF
authors.lastname: Noller
authors.forename: J D
authors.initials: JD
authors.lastname: Puglisi
mesh_terms: D001482:Base Composition; D001483:Base Sequence; D017124:Conserved Sequence; D008958:Models, Molecular; D019906:Nuclear Magnetic Resonance, Biomolecular; D009690:Nucleic Acid Conformation; D009843:Oligoribonucleotides / Q000737:chemistry*; D010458:Peptidyl Transferases / Q000737:chemistry* / Q000378:metabolism*; D012338:RNA, Ribosomal, 23S / Q000737:chemistry* / Q000378:metabolism*; D012270:Ribosomes / Q000378:metabolism* / Q000648:ultrastructure; D013816:Thermodynamics
chemical_list: D009843:Oligoribonucleotides; D012338:RNA, Ribosomal, 23S; D010458:Peptidyl Transferases