title: Usefulness of respiratory gated magnetic resonance coronary angiography in assessing narrowings > or = 50% in diameter in native coronary arteries and in aortocoronary bypass conduits.
abstract: Magnetic resonance coronary angiography (MRCA) is a promising method for the assessment of proximal coronary artery stenosis. Conventional 2-dimensional techniques require repetitive breath holds to image multiple sections. This may lead to misregistrations if the respiratory level is not exactly reproduced. In the present study, MRCA was performed using a 3-dimensional approach with navigator echo-based respiratory gating. In 73 patients (55 men and 18 women) who were referred for cardiac catheterization, the assessment of significant stenoses (> or = 50%) was performed in the proximal and midsegments of the coronary arteries after multiplanar reconstruction of the visualized coronary arteries. In addition, in 8 patients with coronary artery bypass grafts the patency of the transplants was evaluated. After withdrawing 8 patients from analysis because of poor image quality, stenosis evaluation was possible in 236 of 455 reviewed coronary segments (52%). In the other 219 cases, either the visualization of the vessel segment was indistinct (30%) or the segment was located outside the imaging volume (18%). In total, 28 of 43 significant coronary stenoses could be correctly identified (65%). Evaluation of bypass graft patency was possible in 7 patients. All 4 occluded and 13 of 15 patent grafts were correctly classified. Thus, respiratory gated MRCA is a feasable method for the assessment of hemodynamically significant coronary stenoses and bypass graft patency. However, technical improvements are mandatory to improve accuracy of the method.
authors.affiliation: Department of Internal Medicine II, University of Erlangen-Nuernberg, and Siemens Medical Engineering, Erlangen, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Kessler
authors.forename: S
authors.initials: S
authors.lastname: Achenbach
authors.forename: W
authors.initials: W
authors.lastname: Moshage
authors.forename: D
authors.initials: D
authors.lastname: Zink
authors.forename: R
authors.initials: R
authors.lastname: Kroeker
authors.forename: W
authors.initials: W
authors.lastname: Nitz
authors.forename: G
authors.initials: G
authors.lastname: Laub
authors.forename: K
authors.initials: K
authors.lastname: Bachmann
mesh_terms: D000328:Adult; D000368:Aged; D017023:Coronary Angiography / Q000379:methods*; D001026:Coronary Artery Bypass / Q000009:adverse effects*; D003327:Coronary Disease / Q000175:diagnosis*; D005069:Evaluation Studies as Topic; D005260:Female; D006083:Graft Occlusion, Vascular / Q000175:diagnosis*; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014654:Vascular Patency