title: Hufnagel procedure reconverted by endovascular leaflet dislocation and extirpation.
abstract: Before the development of standard aortic valve replacement, Hufnagel treated aortic insufficiency by implanting a ball-valve prosthesis in the descending thoracic aorta. In a patient who, after four major thoracic procedures, ultimately received two mechanical bileaflet valves in series (one in the ascending and one in the descending aorta), the downstream prosthesis became progressively immobilized, with total blockage of the leaflets in the open position due to insufficient transvalvular negative pressure gradient. After evaluation of this particular situation in an experimental model, we predicted blockage of the downstream prosthesis, once the ascending valve had regained normal function, and easily cleared the blockage of the distal valve by removing the two leaflets using balloon inflation. Normal circulation was clinically restored in three separate steps. (a) Normal function was re-established surgically in the ascending aorta position. (b) A second thoracotomy was avoided by endovascular dislocation of both blocked descending thoracic leaflets through endovascular balloon inflation. (c) Both leaflets embolized to the level of the left common iliac artery, where the nearly intact leaflets were removed surgically, finally creating a near-normal circulatory situation.
authors.affiliation: Institute of Biomedical Engineering, University of Ghent, Belgium.
authors.forename: G J
authors.initials: GJ
authors.lastname: Van Nooten
authors.forename: Y
authors.initials: Y
authors.lastname: Taeymans
authors.forename: P
authors.initials: P
authors.lastname: Verdonck
mesh_terms: D001013:Aorta, Thoracic / Q000601:surgery; D001021:Aortic Valve; D001022:Aortic Valve Insufficiency / Q000601:surgery*; D001705:Bioprosthesis / Q000009:adverse effects*; D002404:Catheterization; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D011474:Prosthesis Design; D012086:Reoperation