Malignant melanoma masquerading as malignant fibrous histiocytoma.
Numerous cytological variants of malignant melanoma (MM) exist. We report two cases of MM resembling malignant fibrous histiocytoma (MFH). Pathologists should be aware of this variant. Possible pitfalls that could lead to an incorrect diagnosis are discussed.
Helm
K F
KF
Department of Medicine, The Pennsylvania State University College of Medicine, 17033 U.S.A.
D000368:Aged; D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D001706:Biopsy; D003937:Diagnosis, Differential; D004416:Dysplastic Nevus Syndrome / Q000473:pathology; D015622:Epithelioid Cells / Q000473:pathology; D005534:Foot Diseases / Q000473:pathology; D015726:Giant Cells / Q000473:pathology; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology*; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000473:pathology; D008545:Melanoma / Q000473:pathology*; D009669:Nose Neoplasms / Q000473:pathology; D009418:S100 Proteins / Q000032:analysis; D012878:Skin Neoplasms / Q000473:pathology*; D014746:Vimentin / Q000032:analysis; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D009418:S100 Proteins; D014746:Vimentin; C067980:CD68 antigen, human; D000097382:CD68 Molecule