title: History of perforated duodenal and gastric ulcers.
abstract: Perforated peptic ulcer as a disease entity has been known since 167 BC. Surgical and nonsurgical treatment strategies for perforated peptic ulcer disease were not developed until the latter half of the nineteenth century. The history of the gradual evolution of the various forms of treatment adopted for the conditions over the last century and a half is described.
authors.affiliation: Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong.
authors.forename: W Y
authors.initials: WY
authors.lastname: Lau
authors.forename: C K
authors.initials: CK
authors.lastname: Leow
mesh_terms: D004381:Duodenal Ulcer / Q000150:complications / Q000266:history* / Q000601:surgery; D005743:Gastrectomy; D049671:History, 18th Century; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D010535:Laparoscopy; D010439:Peptic Ulcer Perforation / Q000266:history* / Q000601:surgery; D013276:Stomach Ulcer / Q000150:complications / Q000266:history* / Q000601:surgery; D014628:Vagotomy