Neurotransmitter release at individual sympathetic varicosities, boutons.
The secretosome hypothesis has been studied at autonomic nerve terminals. Evidence is presented that there is a nonuniform secretion probability at different release sites of these terminals. This can be correlated with their influx of calcium ions following an impulse, as expected according to the secretosome hypothesis.
Bennett
M R
MR
Neurobiology Laboratory, University of Sydney, Australia.
D000320:Adrenergic Fibers / Q000502:physiology*; D000818:Animals; D001341:Autonomic Nervous System / Q000502:physiology*; D002118:Calcium / Q000378:metabolism; D015220:Calcium Channels / Q000502:physiology*; D002135:Calcium-Binding Proteins; D005089:Exocytosis / Q000502:physiology*; D008562:Membrane Glycoproteins / Q000502:physiology; D009419:Nerve Tissue Proteins / Q000502:physiology; D018377:Neurotransmitter Agents / Q000378:metabolism*; D011336:Probability; D017783:Superior Cervical Ganglion / Q000502:physiology; D017779:Sympathetic Fibers, Postganglionic / Q000502:physiology; D013569:Synapses / Q000502:physiology*; D009435:Synaptic Transmission; D050857:Synaptotagmins
D015220:Calcium Channels; D002135:Calcium-Binding Proteins; D008562:Membrane Glycoproteins; D009419:Nerve Tissue Proteins; D018377:Neurotransmitter Agents; D050857:Synaptotagmins; D002118:Calcium