title: Estimating correlations from epidemiological data in the presence of measurement error.
abstract: Analysis of a major multi-site epidemiologic study of heart disease has required estimation of the pairwise correlation of several measurements across subpopulations. Because the measurements from each subpopulation were subject to sampling variability, the Pearson product moment estimator of these correlations produces biased estimates. This paper proposes a model that takes into account within and between sub-population variation, provides algorithms for obtaining maximum likelihood estimates of these correlations and discusses several approaches for obtaining interval estimates.
authors.affiliation: Department of Statistics, University of Newcastle, NSW, Australia.
authors.forename: K B
authors.initials: KB
authors.lastname: Dear
authors.forename: M L
authors.initials: ML
authors.lastname: Puterman
authors.forename: A J
authors.initials: AJ
authors.lastname: Dobson
mesh_terms: D000328:Adult; D000368:Aged; D000465:Algorithms; D015982:Bias; D001794:Blood Pressure; D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000453:epidemiology* / Q000209:etiology / Q000517:prevention & control; D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D016013:Likelihood Functions; D008297:Male; D008875:Middle Aged; D012494:Sampling Studies; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology
chemical_list: D002784:Cholesterol