title: Diabetes in midlife: planting genetic time bombs.
authors.forename: S
authors.initials: S
authors.lastname: O'Rahilly
mesh_terms: D000818:Animals; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics* / Q000503:physiopathology; D051275:Glucose Transporter Type 4; D006801:Humans; D006946:Hyperinsulinism / Q000235:genetics; D007328:Insulin / Q000502:physiology; D055504:Insulin Receptor Substrate Proteins; D007333:Insulin Resistance / Q000235:genetics; D007515:Islets of Langerhans / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D008817:Mice, Mutant Strains; D008820:Mice, Obese; D008954:Models, Biological; D009004:Monosaccharide Transport Proteins / Q000096:biosynthesis / Q000235:genetics; D009124:Muscle Proteins; D010750:Phosphoproteins / Q000096:biosynthesis; D011972:Receptor, Insulin / Q000096:biosynthesis
chemical_list: D051275:Glucose Transporter Type 4; C526292:IRS1 protein, human; D007328:Insulin; D055504:Insulin Receptor Substrate Proteins; C526295:Irs1 protein, mouse; D009004:Monosaccharide Transport Proteins; D009124:Muscle Proteins; D010750:Phosphoproteins; C495692:SLC2A4 protein, human; C495693:Slc2a4 protein, mouse; D011972:Receptor, Insulin