Encapsulated filtering blebs after trabeculectomy with mitomycin-C.
OBJECTIVE
To determine the frequency of encapsulated blebs after guarded filtration procedures with mitomycin-C.


METHODS
The authors reviewed the charts of all patients who had undergone a guarded filtration procedure with mitomycin-C. There were 235 patients (283 cases) who had more than 1 month of follow-up.


RESULTS
An encapsulated bleb developed in 7 eyes (2.47%) of 6 patients. Identification of bleb encapsulation occurred at a mean follow-up time of 29.7 +/- 14.6 days after surgery. The mean intraocular pressure at that point was 24.2 +/- 13.5 mm Hg in the affected eyes. Three eyes were treated medically, and needling was performed in 4 eyes.


CONCLUSIONS
There is a low frequency of encapsulated bleb formation after guarded filtration procedures with adjunctive mitomycin-C.
Azuara-Blanco
A
A
Glaucoma Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA.
Bond
J B
JB
Wilson
R P
RP
Moster
M R
MR
Schmidt
C M
CM
D000287:Administration, Topical; D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000188:drug therapy / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage / Q000627:therapeutic use*; D009883:Ophthalmic Solutions; D011183:Postoperative Complications / Q000517:prevention & control / Q000601:surgery; D012189:Retrospective Studies; D014130:Trabeculectomy / Q000009:adverse effects*
D000903:Antibiotics, Antineoplastic; D009883:Ophthalmic Solutions; D016685:Mitomycin