A male with fetal valproate syndrome and autism.
Fetal valproate syndrome (FVS) is characterized by minor craniofacial anomalies, major organ malformations, and developmental delay. We report on a patient who has a clinical phenotype compatible with both FVS and autism. The presence of an autistic disorder in a previously reported case of FVS and similar findings in our patient suggest that a relation between this known teratogen and autism may exist.
Williams
P G
PG
University of Louisville School of Medicine, Child Evaluation Center, Kentucky 40202-3828, USA.
Hersh
J H
JH
D000927:Anticonvulsants / Q000009:adverse effects*; D001298:Audiology; D001321:Autistic Disorder / Q000139:chemically induced*; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007806:Language Disorders / Q000139:chemically induced / Q000175:diagnosis; D008297:Male; D009483:Neuropsychological Tests; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D014635:Valproic Acid / Q000009:adverse effects*
D000927:Anticonvulsants; D014635:Valproic Acid