Chronic inflammation in older people: recognition, consequences, and potential intervention.
In elderly individuals, some chronic inflammatory diseases appear to occur with increased frequency, and recent evidence suggests that some very common chronic, age-related disorders may be propagated and perpetuated by inflammatory processes, perhaps giving rise to the abnormal acute phase protein levels that are seen with increased frequency with aging. The consequences of chronic inflammation in the elderly undoubtedly contribute to excessive morbidity in this population. Treatment of chronic inflammation in the elderly is often difficult, requiring utmost care and close follow-up by a knowledgeable and dedicated physician.
Ballou
S P
SP
Division of Rheumatology, Department of Medicine, MetroHealth Medical Center, Cleveland, Ohio, USA.
Kushner
I
I
D000209:Acute-Phase Proteins; D000210:Acute-Phase Reaction; D000368:Aged; D000375:Aging / Q000502:physiology; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001799:Blood Sedimentation; D002097:C-Reactive Protein; D002908:Chronic Disease; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007249:Inflammation / Q000188:drug therapy / Q000503:physiopathology; D013256:Steroids
D000209:Acute-Phase Proteins; D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D005938:Glucocorticoids; D013256:Steroids; D002097:C-Reactive Protein