Automated feedback control of body temperature for small animal studies with MR microscopy.
A temperature control system consisting of a thermistor, signal processor, and computer algorithm was developed for magnetic resonance (MR) microscopy of small live animals. With control of body temperature within +/- 0.2 degree C of the set point, heart rate is stabilized and, in turn, repetition time (TR) during cardiac-gated studies is less variable. Thus, image quality and resolution are improved.
Qiu
H H
HH
Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA.
Cofer
G P
GP
Hedlund
L W
LW
Johnson
G A
GA
D000818:Animals; D001831:Body Temperature / Q000502:physiology*; D004867:Equipment Design; D005246:Feedback / Q000502:physiology*; D005289:Ferrets; D006168:Guinea Pigs; D008279:Magnetic Resonance Imaging; D051379:Mice; D008853:Microscopy; D008954:Models, Biological; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods; D051381:Rats; D012121:Respiration, Artificial; D012815:Signal Processing, Computer-Assisted; D013821:Thermometers