Functional magnetic resonance neuroimaging data acquisition techniques.
Functional MRI studies of human brain require rapid data acquisition techniques, to map dynamic changes with sufficient anatomical coverage. In addition, task activation studies employing functional MRI require a high scan sensitivity, in order to discriminate the small, activation-related signal changes from background noise. An overview is given of current fast scan methods, which are sensitized to detect susceptibility changes related to task-induced changes in blood oxygenation. Sources of artifacts are discussed, as well as their effect on image quality.
Duyn
J H
JH
Laboratory of Diagnostic Radiology Research, OIR, NIH, Bethesda, Maryland 20892, USA. jhd@helix.nih.gov
Yang
Y
Y
Frank
J A
JA
Mattay
V S
VS
Hou
L
L
D016477:Artifacts; D001921:Brain / Q000098:blood supply*; D001931:Brain Mapping / Q000295:instrumentation*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging / Q000295:instrumentation*; D010101:Oxygen Consumption / Q000502:physiology; D012039:Regional Blood Flow / Q000502:physiology; D012680:Sensitivity and Specificity