Effects of embryo reduction from trichorionic triplets to twins.
Sixty-six trichorionic triplet pregnancies reduced to twins were compared with 47 triplet pregnancies that were not reduced. The miscarriage rate was higher (7.6% compared with 2.6%) but the number delivering between 24 and 32 weeks was lower (8.2% compared with 24.0%). Since severe preterm delivery is associated with risks of neonatal death and severe handicap, embryo reduction of triplets to twins may not improve the chance of survival but may reduce the rate of handicap.
Sebire
N J
NJ
Harris Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, Denmark Hill, London, UK.
D'Ercole
C
C
Sepulveda
W
W
Hughes
K
K
Nicolaides
K H
KH
D000022:Abortion, Spontaneous / Q000453:epidemiology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D008131:London / Q000453:epidemiology; D007752:Obstetric Labor, Premature / Q000453:epidemiology; D011247:Pregnancy; D018607:Pregnancy Reduction, Multifetal / Q000009:adverse effects*; D012307:Risk Factors; D014310:Triplets; D014427:Twins