title: Argentinian collaborative study on prevalence of erythromycin and penicillin susceptibility in Streptococcus pyogenes. The Argentinian Streptococcus Study Group.
abstract: Two monthly studies on the prevalence of penicillin and erythromycin susceptibility of Streptococcus pyogenes were performed in May and October of 1994 in Argentina. A total of 58 centers from 27 cities participated in these studies. A total of 1072 isolates were tested by a diffusion method, although 595 isolates were tested both by the diffusion and an agar dilution method (n = 1767 isolates). No penicillin-resistant streptococci were found in our study (MIC100 = 0.03 microgram/ml). Only four isolates were confirmed as erythromycin resistant S. pyogenes (prevalence 0.14 and 0.28% in May and October 1994, respectively). Resistance in three isolates was due to an inducible mechanism, although in one strain a different phenotype was observed.
authors.affiliation: Hospital de Pediatria Prof. Dr. Juan P. Garrahan, Universidad Católica Argentina, Buenos Aires, Buenos Aires, Argentina.
authors.forename: H A
authors.initials: HA
authors.lastname: Lopardo
authors.forename: M E
authors.initials: ME
authors.lastname: Venuta
authors.forename: P
authors.initials: P
authors.lastname: Vidal
authors.forename: L
authors.initials: L
authors.lastname: Rosaenz
authors.forename: C
authors.initials: C
authors.lastname: Corthey
authors.forename: A
authors.initials: A
authors.lastname: Farinati
authors.forename: E
authors.initials: E
authors.lastname: Couto
authors.forename: B
authors.initials: B
authors.lastname: Sarachian
authors.forename: M
authors.initials: M
authors.lastname: Sparo
authors.forename: S
authors.initials: S
authors.lastname: Kaufman
authors.forename: C A
authors.initials: CA
authors.lastname: De Mier
authors.forename: L
authors.initials: L
authors.lastname: Gubbay
authors.forename: V
authors.initials: V
authors.lastname: Scilingo
authors.forename: P
authors.initials: P
authors.lastname: Villaverde
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001118:Argentina; D004352:Drug Resistance, Microbial; D004917:Erythromycin / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D010403:Penicillin Resistance; D010406:Penicillins / Q000494:pharmacology*; D013297:Streptococcus pyogenes / Q000187:drug effects* / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins; D004917:Erythromycin