Autologous transplantation of G-CSF mobilized bone marrow cells in a child with disseminated fibrosarcoma.
We report a very rapid engraftment after reinfusion of bone marrow cells derived from 'G-CSF-primed bone marrow' in a small child. As the hemopoietic recovery was equal to that seen after PBSCT, we suggest that the use of 'mobilized bone marrow' is a good alternative for PBSCT in children if contraindications to the collection of PBSCT are present.
Hoogerbrugge
P M
PM
Dept of Pediatric Hemato-Oncology, Sophia Children's Hospital, Rotterdam, The Netherlands.
Egeler
R M
RM
D016026:Bone Marrow Transplantation; D005354:Fibrosarcoma / Q000473:pathology / Q000628:therapy*; D005534:Foot Diseases / Q000473:pathology*; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage*; D019650:Hematopoietic Stem Cell Mobilization; D006801:Humans; D007223:Infant; D008297:Male; D009362:Neoplasm Metastasis; D012983:Soft Tissue Neoplasms / Q000473:pathology / Q000628:therapy*; D014182:Transplantation, Autologous
D016179:Granulocyte Colony-Stimulating Factor