title: Gene transfer trials in clinical haematology.
abstract: The haematopoietic stem cells in the bone marrow have long been considered, at least in theory, as an ideal target for gene therapy. Of the more than 250 clinical gene transfer protocols reported from around the world up to December 1996, almost one in three involves manipulation of haematopoietic cells. This includes both marketing trials and trials with a therapeutic intent. The human gene transfer trials targeting haematopoietic cells, the knowledge gained from them and their limitations are briefly summarized.
authors.affiliation: Gene Therapy Center, University of Lund, Sweden.
authors.forename: J
authors.initials: J
authors.lastname: Richter
mesh_terms: D002986:Clinical Trials as Topic; D018014:Gene Transfer Techniques; D006801:Humans