title: Anatomical consideration for an implantable centrifugal biventricular assist system.
abstract: A miniaturized pivot bearing-supported centrifugal blood pump (Gyro PI) has been developed as a long-term biventricular assist system (BiVAS). In this study we determined the anatomical configuration of this system using a bovine model. Under general anesthesia, a left lateral thoracotomy was performed to open the chest. Two Gyro PI-601 pumps for left and right assists were placed in the preperitoneal pocket by a subcostal abdominal incision. The left pump could be placed along the dome of the diaphragm just beneath the apex of the left ventricle. The right pump could be placed next to the left pump. The inlet and outlet ports of both pumps penetrated the diaphragm. The inlet port of the left pump, with a length of 55 mm, was inserted directly into the apex of the left ventricle. A woven Dacron graft (150 mm long, 11 mm inner diameter) was placed between the outlet port of the left pump and the descending aorta. As for the right pump, a 100 mm long and 120 degree angled inflow conduit was placed between the inlet port and the right ventricular infundibulum. The outlet port of the right pump was connected to the main trunk of the pulmonary artery using a 90 mm long, 11 mm inner diameter Dacron graft. We could perform biventricular assistance to confirm the anatomical feasibility of the Gyro implantable centrifugal BiVAS.
authors.affiliation: Department of Surgery, Baylor College of Medicine, Houston, Texas, U.S.A.
authors.forename: Y
authors.initials: Y
authors.lastname: Takami
authors.forename: T
authors.initials: T
authors.lastname: Nakazawa
authors.forename: G
authors.initials: G
authors.lastname: Otsuka
authors.forename: E
authors.initials: E
authors.lastname: Tayama
authors.forename: Y
authors.initials: Y
authors.lastname: Ohashi
authors.forename: A
authors.initials: A
authors.lastname: Sueoka
authors.forename: H
authors.initials: H
authors.lastname: Schima
authors.forename: H
authors.initials: H
authors.lastname: Schmallegger
authors.forename: E
authors.initials: E
authors.lastname: Wolner
authors.forename: Y
authors.initials: Y
authors.lastname: Nosé
mesh_terms: D000818:Animals; D002417:Cattle; D002498:Centrifugation; D006352:Heart Ventricles / Q000033:anatomy & histology*; D006353:Heart-Assist Devices; D008953:Models, Anatomic; D019919:Prosthesis Implantation / Q000379:methods*