[Sympathoadrenal activity during the treatment of patients with cancer of the stomach and large intestine].
Excretion was studied of catecholamines and diphenilamine (DOPA) in 310 patients with carcinoma of the stomach and large intestine and 43 patients with non-malignant diseases. The oncological patients showed decrease in activity of the mediator link of the sympathoadrenal system (SAS) as well as its reserves but there was no association with sex, age, location or histological structure. Three types of SAS functioning were identified, such as compensation, overstrain and emaciation. Surgical intervention led to activation of the hormonal link and exhaustion of the system's reserves. Two kinds of sympathoadrenal response to stress were described--adequate and inadequate. In the former type, phases of stress remain as they are, unchanged, as are time periods of formation thereof, while under the latter one time periods of the phases formation or formation thereof get disordered.
Ial'chenko
N A
NA
D000311:Adrenal Glands / Q000503:physiopathology*; D002395:Catecholamines / Q000652:urine; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000503:physiopathology* / Q000601:surgery / Q000652:urine; D007420:Intestine, Large / Q000601:surgery; D008297:Male; D011184:Postoperative Period; D018709:Statistics, Nonparametric; D013274:Stomach Neoplasms / Q000503:physiopathology* / Q000601:surgery / Q000652:urine; D013564:Sympathetic Nervous System / Q000503:physiopathology*
D002395:Catecholamines