Progressive sensorineural hearing loss, subjective tinnitus and vertigo caused by elevated blood lipids.
The otologist frequently sees patients with progressive sensorineural hearing loss, subjective aural tinnitus and vertigo with no apparent cause. Elevated blood lipids may be a cause of inner ear malfunction on a biochemical basis. To establish the true incidence of this condition, all new patients (4,251) seen during an eight-year period were evaluated; of these, 2,332 patients had complaints of inner ear disease. All had a complete neurotologic examination, appropriate audiometric and vestibular studies and imaging, and blood tests including lipid phenotype studies. Hyperlipoproteinemia was found in 120 patients (5.1%). Most patients were found to be overweight and had additional coexisting conditions such as diabetes mellitus. Treatment with vasodilators and a 500-calorie, high-protein, low-carbohydrate diet yielded improvement of symptoms in 83% of patients within five months of initiation of treatment.
Pulec
J L
JL
Pulec Ear Clinic and Ear International, Los Angeles, California, USA.
Pulec
M B
MB
Mendoza
I
I
D000328:Adult; D000368:Aged; D001301:Audiometry, Pure-Tone; D002784:Cholesterol / Q000097:blood; D003131:Combined Modality Therapy; D048909:Diabetes Complications; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D006951:Hyperlipoproteinemias / Q000150:complications* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D014012:Tinnitus / Q000209:etiology*; D014280:Triglycerides / Q000097:blood; D014665:Vasodilator Agents / Q000627:therapeutic use; D014717:Vertigo / Q000209:etiology*
D014280:Triglycerides; D014665:Vasodilator Agents; D002784:Cholesterol