title: A result on a 2 x 2 survival experiment.
abstract: Lifetime data classified according to categorical variables under the proportionality of the hazard functions of response variables for various treatment combinations is assumed. The proposed model is a combination of Cox's proportional hazards model and ANOVA model. The existence of a solution to the marginal likelihood function is examined for the case of 2 x 2 two-way classification. We provide an easily verifiable condition for the existence of a unique estimate.
authors.affiliation: Division of Biometry and Risk Assessment, National Center for Toxicological Research, Jefferson, Arkansas 72079-9502, USA.
authors.forename: R B
authors.initials: RB
authors.lastname: Arani
authors.forename: M B
authors.initials: MB
authors.lastname: Rao
mesh_terms: D006801:Humans; D015993:Life Tables; D008433:Mathematics; D011336:Probability; D016016:Proportional Hazards Models; D016019:Survival Analysis