Leptomeningeal metastasis from a paraspinal rhabdomyosarcoma with a der(13)t(1;13)(q23;q32) in a 14-month-old boy.
Cytogenetic analysis performed on a 14-month-old boy with a primary retroperitoneal/paraspinal alveolar rhabdomyosarcoma showed the presence of a der(13)t(1;13)(q23;q32) resulting in partial trisomy of the 1q23-->qter region and loss of the 13q32-->qter region. The present case is discussed with reference to a similar case reported in the literature.
Kline
R M
RM
Department of Pediatrics, University of Louisville, Kentucky 40202, USA.
Oseas
R S
RS
Jolley
S G
SG
Reyna
T M
TM
Erling
M A
MA
Sandberg
A A
AA
Meloni
A M
AM
D002878:Chromosomes, Human, Pair 1; D002882:Chromosomes, Human, Pair 13; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008297:Male; D008577:Meningeal Neoplasms / Q000235:genetics* / Q000556:secondary; D018232:Rhabdomyosarcoma, Alveolar / Q000235:genetics* / Q000473:pathology; D012983:Soft Tissue Neoplasms / Q000235:genetics* / Q000473:pathology; D013131:Spine; D014178:Translocation, Genetic