title: Treatment of condylomata acuminata with oral isotretinoin.
abstract: OBJECTIVE
  The aim of our study was to evaluate the efficacy and safety of oral isotretinoin in the treatment of condylomata acuminata.
  
  
  METHODS
  A total of 56 male patients with a history of condylomata acuminata refractory to at least 1 standard therapeutic regimen was treated orally with isotretinoin (1 mg./kg. daily) during a 3-month period.
  
  
  RESULTS
  At the end of treatment 21 of the 53 evaluated patients (39.6%) had complete response, 7 (13.2%) had partial response and 25 (47.1%) had no response. A statistically significant inverse relationship was found between age and area of treated lesions and response to medication. Two complete responders (9.5%) revealed recurrence during the 1-year followup.
  
  
  CONCLUSIONS
  Oral isotretinoin may be regarded as an effective, fairly well tolerated and noninvasive alternative form of therapy for immature and small condylomata acuminata.
authors.affiliation: Department of Dermatology, University of Patras, Greece.
authors.forename: D
authors.initials: D
authors.lastname: Tsambaos
authors.forename: S
authors.initials: S
authors.lastname: Georgiou
authors.forename: A
authors.initials: A
authors.lastname: Monastirli
authors.forename: T
authors.initials: T
authors.lastname: Sakkis
authors.forename: A
authors.initials: A
authors.lastname: Sagriotis
authors.forename: G
authors.initials: G
authors.lastname: Goerz
mesh_terms: D000284:Administration, Oral; D000328:Adult; D003218:Condylomata Acuminata / Q000188:drug therapy*; D005832:Genital Diseases, Male / Q000188:drug therapy*; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged
chemical_list: D015474:Isotretinoin