title: Multiple pulmonary nodules in association with pyoderma gangrenosum.
abstract: This report describes a patient with extensive pyoderma gangrenosum in whom there were co-existent lung abnormalities. The patient's X-ray showed peripherally sited multiple pulmonary lesions bilaterally. A lung biopsy showed chronic non-specific inflammatory changes with neutrophil and lymphocyte infiltration which were similar to the skin lesions. This case was diagnosed as multiple aseptic nodules in pyoderma gangrenosum. The pulmonary infiltrative shadows were controlled only with prednisolone treatment. Steroid therapy is considered to be the first choice to control pulmonary lesions of this disease.
authors.affiliation: First Department of Internal Medicine, Tokyo Medical College, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Kasuga
authors.forename: N
authors.initials: N
authors.lastname: Yanagisawa
authors.forename: C
authors.initials: C
authors.lastname: Takeo
authors.forename: M
authors.initials: M
authors.lastname: Koga
authors.forename: H
authors.initials: H
authors.lastname: Kiyokawa
authors.forename: M
authors.initials: M
authors.lastname: Yonemaru
authors.forename: Y
authors.initials: Y
authors.lastname: Ichinose
authors.forename: K
authors.initials: K
authors.lastname: Toyama
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D006801:Humans; D008171:Lung Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D017511:Pyoderma Gangrenosum / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D011859:Radiography
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone