title: Viral infections of nonhuman primates.
abstract: Approximately 53,000 serologic tests and viral isolation studies were performed on 1,700 nonhuman primate specimens for evidence of past and/or current viral infection. Information, other than the requested test, generally was not provided with the specimen. This lack of information does not permit any attempt at interpretation of results. Requested testing included a large number of diverse viral agents in approximately 40 primate species. The resulting data are in keeping with those of previous studies and offer an insight into the needs of colony management, as well as some general information on the overall frequency of infection with the indicated viruses. Inasmuch as the results represent testing of single specimens, they are not to be construed as "diagnostic," and simply indicate past infection as represented by the presence of antibody in the test animal. Viral isolation results are listed, and the number of positive results versus the number of animals tested emphasizes the limitations of the procedure. Investigations such as these continue to assist in the maintenance of healthy nonhuman primate colonies. This information also supports continued use of nonhuman primates for research in human viral infections and may be helpful in terms of animal selection for use in xenotransplants.
authors.affiliation: Virus Reference Laboratory, Inc. (VRL), San Antonio, Texas 78229, USA.
authors.forename: S S
authors.initials: SS
authors.lastname: Kalter
authors.forename: R L
authors.initials: RL
authors.lastname: Heberling
authors.forename: A W
authors.initials: AW
authors.lastname: Cooke
authors.forename: J D
authors.initials: JD
authors.lastname: Barry
authors.forename: P Y
authors.initials: PY
authors.lastname: Tian
authors.forename: W J
authors.initials: WJ
authors.lastname: Northam
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000032:analysis; D018420:Ape Diseases / Q000175:diagnosis / Q000821:virology*; D019084:Fluorescent Antibody Technique, Indirect / Q000662:veterinary; D000882:Haplorhini / Q000821:virology*; D006801:Humans; D015151:Immunoblotting / Q000662:veterinary; D007124:Immunoenzyme Techniques / Q000662:veterinary; D008992:Monkey Diseases / Q000175:diagnosis / Q000821:virology*; D012698:Serologic Tests / Q000662:veterinary; D014777:Virus Diseases / Q000175:diagnosis / Q000662:veterinary* / Q000821:virology; D014780:Viruses / Q000276:immunology / Q000302:isolation & purification
chemical_list: D000914:Antibodies, Viral