title: Structure of benzyl T-antigen disaccharide bound to Amaranthus caudatus agglutinin.
abstract: Amaranthus caudatus agglutinin contains a novel arrangement of four beta-trefoil domains. The sugar-binding site provides specificity for the carcinoma-associated T-antigen disaccharide even when 'masked' by other sugars.
authors.forename: T R
authors.initials: TR
authors.lastname: Transue
authors.forename: A K
authors.initials: AK
authors.lastname: Smith
authors.forename: H
authors.initials: H
authors.lastname: Mo
authors.forename: I J
authors.initials: IJ
authors.lastname: Goldstein
authors.forename: M A
authors.initials: MA
authors.lastname: Saper
mesh_terms: D000957:Antigens, Viral, Tumor / Q000737:chemistry*; D001593:Benzyl Compounds; D018360:Crystallography, X-Ray / Q000379:methods; D019281:Dimerization; D004187:Disaccharides; D002523:Edible Grain; D037102:Lectins / Q000737:chemistry*; D008958:Models, Molecular; D037121:Plant Lectins; D011487:Protein Conformation; D054788:Ribosome Inactivating Proteins; D054789:Ribosome Inactivating Proteins, Type 1; D012639:Seeds
chemical_list: D000957:Antigens, Viral, Tumor; D001593:Benzyl Compounds; D004187:Disaccharides; D037102:Lectins; D037121:Plant Lectins; D054789:Ribosome Inactivating Proteins, Type 1; C061152:amaranthin protein, Amaranthus; D054788:Ribosome Inactivating Proteins