Anti-E as a cause of hemolytic disease of the newborn.
A case of HDN caused by anti-E antibody is reported. A group A, E-positive, hemoglobin E trait female infant was born from a group A, E-negative, beta-thalassemia/hemoglobin E mother. Hyperbilirubinemia was noted at the first day of life. The DAT was positive. Anti-E was detected in the maternal serum. Jaundice and anemia occurring to the baby were severe enough to require phototherapy intervention for 9 days and 50 ml of group A, E-negative packed red blood cells was transfused. The baby's condition improved. She was discharged at 12 days of age. Follow-up of the baby at 1 year old showed that she was alive and in good health.
Cheepsattayakorn
R
R
Department of Pathology, Faculty of Medicine, Chiang Mai University, Thailand.
Fongsatitkul
L
L
Chotinaruemol
S
S
Mahawongtong
M
M
D000017:ABO Blood-Group System / Q000235:genetics; D000328:Adult; D004899:Erythroblastosis, Fetal / Q000097:blood / Q000209:etiology*; D005260:Female; D005838:Genotype; D006454:Hemoglobins / Q000235:genetics; D006801:Humans; D007231:Infant, Newborn; D007518:Isoantibodies / Q000276:immunology*; D012204:Rh-Hr Blood-Group System / Q000235:genetics / Q000276:immunology*
D000017:ABO Blood-Group System; D006454:Hemoglobins; D007518:Isoantibodies; D012204:Rh-Hr Blood-Group System