Malignant evolution of presumed benign lesions in the brain in neurofibromatosis: case report.
We report a patient suffering from neurofibromatosis type 1 in whom neoplasms developed from the areas of altered signal which are generally considered benign and typical of the disease. MRI, despite two previous examinations 3 and 2 years before development of the tumour, gave no clue to an unfavourable outcome.
Carella
A
A
Servizio di Neuroradiologia Policlinico-A.S.L., Bari, Italy.
Medicamento
N
N
D000328:Adult; D001139:Arnold-Chiari Malformation / Q000235:genetics / Q000473:pathology; D001254:Astrocytoma / Q000235:genetics / Q000473:pathology; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000235:genetics / Q000473:pathology*; D002528:Cerebellar Neoplasms / Q000235:genetics / Q000473:pathology; D005500:Follow-Up Studies; D006580:Genetic Carrier Screening; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000235:genetics / Q000473:pathology; D009456:Neurofibromatosis 1 / Q000235:genetics / Q000473:pathology*