title: Lupus-related mitral valve disease: embolic coronary occlusion as a unique cause of myocardial infarction.
abstract: Early diagnosis and greatly improved treatment have markedly altered the clinical evolution of systemic lupus erythematosus; the pattern of cardiac involvement in lupus has also changed. To illustrate this, a young woman who died from severe mitral valve disease, including a coronary embolus from verrucous endocarditis, is presented. Mitral valve involvement in lupus is no longer limited to the small benign lesions described by Libman and Sacks.
authors.affiliation: Division of Cardiology, Hartford Hospital, Connecticut 06102-5037, USA. sgiri@harthosp.org
authors.forename: S
authors.initials: S
authors.lastname: Giri
authors.forename: A L
authors.initials: AL
authors.lastname: Parke
authors.forename: J
authors.initials: J
authors.lastname: Mangion
authors.forename: J
authors.initials: J
authors.lastname: Hasson
authors.forename: L
authors.initials: L
authors.lastname: Gillam
authors.forename: D D
authors.initials: DD
authors.lastname: Waters
mesh_terms: D000293:Adolescent; D004617:Embolism / Q000175:diagnosis / Q000209:etiology*; D004696:Endocarditis / Q000175:diagnosis / Q000209:etiology; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008943:Mitral Valve / Q000473:pathology; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000209:etiology*; D009203:Myocardial Infarction / Q000175:diagnosis / Q000209:etiology*