title: Peripheral osteoarticular tuberculosis in children: tumor-like bone lesions.
abstract: Osteoarticular tuberculosis in children is rare in developed countries. We report three patients who were monitored between 3 1/2 years and 8 years. The primary focus was located in the distal epiphysis of the femur, distal epiphysis of the tibia, and the calcaneus. The lesions were initially radiolucent and ill defined, appearing afterward surrounded by a sclerosis halo; these features may disguise them as other infectious lesions or pseudotumoral processes. A poorly defined set of symptoms and a lack of specific signs may delay their diagnosis and treatment. Histopathological examination and culture identification are in the most accurate methods to reach a definitive diagnosis. Lesion scrapping and chemotherapy during sat least 9 months was effective in two patients.
authors.affiliation: Department of Orthopaedic Surgery, Hospital Universitario de Valme, Seville, Spain.
authors.forename: J
authors.initials: J
authors.lastname: González Herranz
authors.forename: D M
authors.initials: DM
authors.lastname: Farrington
authors.forename: J
authors.initials: J
authors.lastname: Angulo Gutiérrez
authors.forename: P
authors.initials: P
authors.lastname: Rodriguez Ferrol
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use; D002111:Calcaneus / Q000000981:diagnostic imaging; D002648:Child; D002675:Child, Preschool; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013977:Tibia / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D014394:Tuberculosis, Osteoarticular / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D014457:Ulna / Q000000981:diagnostic imaging
chemical_list: D000995:Antitubercular Agents