title: Retrograde migration of starch in the genital tract of rabbits.
abstract: This study in a rabbit model simulates contamination with glove powder in association with a routine gynaecological examination. Large individual variations of powder contamination were found and there were no overall statistically significant differences between the control and experimental animals. The findings are supported by the observation that some but not all women develop adhesions after gynaecological surgery. Analyzes of variances indicate differences in the migration of starch particles in the genital tract with the highest amount of particles found three days after starch contamination of the vagina. Since no adhesions were observed, there would probably need to be an ongoing post surgical or post infectious inflammation in the tissue, when the starch particles are added. Starch powder from latex gloves can cause adhesions and increase the risk of latex allergy in healthcare workers. Retrograde migration in the genital tract cannot be excluded, powdered examination products should be eliminated from the gynecologicla examination room.
authors.affiliation: Department of Obstetrics and Gynaecology, SOS, Karolinska Institute, Sweden.
authors.forename: G A
authors.initials: GA
authors.lastname: Edelstam
authors.forename: A C
authors.initials: AC
authors.lastname: Sjösten
authors.forename: H
authors.initials: H
authors.lastname: Ellis
mesh_terms: D000818:Animals; D001202:Ascitic Fluid / Q000378:metabolism; D005260:Female; D005836:Genitalia, Female / Q000378:metabolism; D005932:Gloves, Surgical / Q000009:adverse effects; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects; D006801:Humans; D006820:Hyaluronic Acid / Q000493:pharmacokinetics; D007249:Inflammation / Q000209:etiology; D011208:Powders / Q000009:adverse effects / Q000493:pharmacokinetics; D011817:Rabbits; D013213:Starch / Q000009:adverse effects / Q000493:pharmacokinetics*; D000267:Tissue Adhesions / Q000209:etiology; D014621:Vagina / Q000378:metabolism
chemical_list: D011208:Powders; D006820:Hyaluronic Acid; D013213:Starch