title: Splenectomy in cancer gastrectomy: recommendation of spleen-preserving for early stages.
abstract: BACKGROUND
  The prognostic significance of splenectomy in cancer gastrectomy was reevaluated, in terms of postoperative survival rate, retrospectively.
  
  
  METHODS
  The cumulative survival rates between a splenectomized group (n = 272) and a nonsplenectomized group (n = 192) were compared.
  
  
  RESULTS
  The five-, ten- and fifteen-year survival rates were significantly higher in the nonsplenectomized group in total. When the cancer was classified, according to intraoperative gross findings of the degree of serosal invasion, penetration into adjacent organs and metastases, the five-year cumulative survival rate for Stage I and II patients was significantly higher in the nonsplenectomized group. No significant difference was found between the two groups of Stage II in any of the one- to fifteen-year survival rates. The one-year survival rate for Stage IV patients in the splenectomized group was higher than that in the nonsplenectomized group.
  
  
  CONCLUSIONS
  The splenectomy should be limited to the Stage III or IV patients with some specific findings.
authors.affiliation: Department of Surgery, Keio University School of Medicine, Tokyo, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Yoshino
authors.forename: Y
authors.initials: Y
authors.lastname: Yamada
authors.forename: F
authors.initials: F
authors.lastname: Asanuma
authors.forename: K
authors.initials: K
authors.lastname: Aizawa
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016009:Chi-Square Distribution; D000075202:Contraindications; D005260:Female; D005743:Gastrectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011379:Prognosis; D012189:Retrospective Studies; D013156:Splenectomy; D013274:Stomach Neoplasms / Q000401:mortality / Q000601:surgery*; D015996:Survival Rate