title: Association between allele 1 of T102C polymorphism, 5-hydroxytryptamine 2a receptor gene and schizophrenia in Chinese males in Singapore.
abstract: The T102C polymorphism at the 5-hydroxytryptamine 2a receptor (5HTR2a) gene was studied in 101 Chinese male schizophrenics and 103 controls. Genotyping revealed a predominance of allele 1 among schizophrenics. This is in contrast to previous reports in Caucasians and Japanese which showed an association of allele 2 of this polymorphism with schizophrenia.
authors.affiliation: Institute of Molecular and Cell Biology, National University of Singapore, Republic of Singapore. mcbtayhn@nus.sg
authors.forename: A H
authors.initials: AH
authors.lastname: Tay
authors.forename: L C
authors.initials: LC
authors.lastname: Lim
authors.forename: W L
authors.initials: WL
authors.lastname: Lee
authors.forename: K E
authors.initials: KE
authors.lastname: Wong
authors.forename: L Y
authors.initials: LY
authors.lastname: Wong
authors.forename: W F
authors.initials: WF
authors.lastname: Tsoi
mesh_terms: D000483:Alleles; D044466:Asian People / Q000235:genetics*; D005787:Gene Frequency; D005796:Genes; D005838:Genotype; D006801:Humans; D015810:Linkage Disequilibrium; D008297:Male; D011110:Polymorphism, Genetic; D011985:Receptors, Serotonin / Q000235:genetics*; D012559:Schizophrenia / Q000453:epidemiology* / Q000235:genetics*; D012846:Singapore / Q000453:epidemiology
chemical_list: D011985:Receptors, Serotonin