Oxidative damage and fragmentation of mitochondrial DNA in cellular apoptosis.
The molecular genetics and bioenergetics of oxidative damage, fragmentation, and fragility of mitochondrial DNA in cellular apoptosis is reviewed in connection with the "redox mechanism of ageing."
Ozawa
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Department of Biomedical Chemistry, Faculty of Medicine, University of Nagoya, Japan.
D000375:Aging; D000818:Animals; D017209:Apoptosis / Q000235:genetics*; D053938:DNA Fragmentation; D004272:DNA, Mitochondrial / Q000502:physiology*; D006801:Humans; D018384:Oxidative Stress
D004272:DNA, Mitochondrial