Bereitschaftpotential in schizophrenia.
BACKGROUND
Several reports have documented the presence of motor abnormalities in schizophrenic patients.


METHODS
Thirty schizophrenics and 28 healthy controls were included in the study. Scalp-recorded bereitschaftpotentials (BPs) generated prior to voluntary movements were recorded in all subjects.


RESULTS
The early (NSI) and late components of BP and peak negativity were reduced in all schizophrenic patients. In particular, the NSI was reduced in patients with positive symptoms, and the late component in patients with negative symptoms.


CONCLUSIONS
These findings provide further support of the involvement of frontal cortex, subcortical structures and their connections in schizophrenia, and highlight some differences between positive and negative symptom clusters.
Karaman
T
T
University Medical Faculty, Antalya, Turkey.
Ozkaynak
S
S
Yaltkaya
K
K
Büyükberker
C
C
D000328:Adult; D003265:Contingent Negative Variation / Q000502:physiology*; D004576:Electromyography; D005260:Female; D006801:Humans; D008297:Male; D011596:Psychomotor Disorders / Q000209:etiology* / Q000503:physiopathology; D012559:Schizophrenia / Q000150:complications / Q000503:physiopathology*