New angles on actin dynamics.
Actin is now realised to play a dynamic role in muscle contraction and many cellular motility events that occur when the motor domain of myosin uses the energy of ATP hydrolysis to move along the actin filament. Optical and electron microscopic studies have led to seemingly contradictory pictures of actin filament dynamics.
Egelman
E H
EH
Department of Cell Biology and Neuroanatomy, University of Minnesota Medical School, Minneapolis 55455, USA. egelman@egel2.med.umn.edu
D008841:Actin Cytoskeleton / Q000648:ultrastructure; D051339:Actin Depolymerizing Factors; D000199:Actins / Q000737:chemistry / Q000378:metabolism* / Q000648:ultrastructure*; D008840:Microfilament Proteins / Q000378:metabolism / Q000648:ultrastructure; D008854:Microscopy, Electron; D009119:Muscle Contraction / Q000502:physiology; D011487:Protein Conformation
D051339:Actin Depolymerizing Factors; D000199:Actins; D008840:Microfilament Proteins