title: Infraorbital crease and atopic dermatitis.
abstract: The usefulness of a prominent infraorbital skin crease as a marker of atopic dermatitis (AD) was examined in 500 consecutive school children 3 to 11 years of age. Infraorbital crease was recorded by two trained observers according to a strict protocol, and AD was determined by an independent dermatologist who was blinded to the study design. A prominent infraorbital crease was present in only 4 of 20 (20%) children with AD, compared with 171 of 480 (35.6%) children who did not have AD (p > .05). While infraorbital crease may be of some use in diagnosing individual cases of AD in a hospital setting, it appears to be less useful in population-based studies because of its poor validity and repeatability.
authors.affiliation: Department of Dermatology & Venereology, Government Medical College Hospital, Chandigarh, India.
authors.forename: I
authors.initials: I
authors.lastname: Singh
authors.forename: A J
authors.initials: AJ
authors.lastname: Kanwar
mesh_terms: D002648:Child; D002675:Child, Preschool; D003876:Dermatitis, Atopic / Q000175:diagnosis*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D009915:Orbit