title: [The immunomodulating effect of vilozen in the combined treatment of children with rheumatism associated with an allergy].
abstract: Effects were traced out of vilosene alone and combination with ketotifene on clinical-and-immunologic parameters in 86 children with rheumatism associated with concurrent allergy. There has been disclosed immunomodulating effect of vilosene in hyposuppressor variant of a secondary immune deficient state in rheumatic children. Antiallergic action of vilosene is more pronounced when employed in combination with ketotifene. The clinical effect was evident 1-1.5 weeks earlier than in controls. The data obtained suggest vilosene and ketotifen to be useful in the treatment of rheumatic children presenting with concurrent allergy.
authors.forename: P S
authors.initials: PS
authors.lastname: Moshchych
authors.forename: N M
authors.initials: NM
authors.lastname: Petrenko
mesh_terms: D000208:Acute Disease; D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000293:Adolescent; D018926:Anti-Allergic Agents / Q000627:therapeutic use; D000917:Antibody Formation / Q000187:drug effects; D004341:Drug Evaluation; D004342:Drug Hypersensitivity / Q000188:drug therapy* / Q000276:immunology; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007665:Ketotifen / Q000627:therapeutic use; D008297:Male; D012214:Rheumatic Heart Disease / Q000188:drug therapy* / Q000276:immunology; D013949:Thymus Extracts / Q000627:therapeutic use*
chemical_list: D000276:Adjuvants, Immunologic; D018926:Anti-Allergic Agents; D013949:Thymus Extracts; C059606:iilozen; D007665:Ketotifen