title: Activity of selected beta-lactams, ciprofloxacin, and amikacin against different Acinetobacter baumannii biotypes from Chilean hospitals.
abstract: The activity of some third generation cephalosporins, aztreonam, imipenem, ciprofloxacin, and amikacin against isolates of Acinetobacter baumannii of various biotypes has been studied. The isolates, independently of the biotype, exhibited a broad multiresistance against cephalosporins. Ceftazidime was the most active and cefoperazone the least active compound. Aztreonam also showed low activity and no imipenem-resistant strains were found. Ciprofloxacin and amikacin were somewhat more active than cephalosporins, but resistant isolates were also frequent. Isolates of Biotypes 9 and 8 exhibited broader multiresistance than those of Biotype 6 and "other."
authors.affiliation: Departamento de Microbiologia, Facultad de Ciencias Biologicas, Universidad de Concepcion, Chile.
authors.forename: H
authors.initials: H
authors.lastname: Bello
authors.forename: G
authors.initials: G
authors.lastname: Gonzalez
authors.forename: M
authors.initials: M
authors.lastname: Dominguez
authors.forename: R
authors.initials: R
authors.lastname: Zemelman
authors.forename: A
authors.initials: A
authors.lastname: Garcia
authors.forename: S
authors.initials: S
authors.lastname: Mella
mesh_terms: D000150:Acinetobacter / Q000145:classification / Q000187:drug effects*; D000151:Acinetobacter Infections / Q000382:microbiology; D000583:Amikacin / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000494:pharmacology*; D015373:Bacterial Typing Techniques; D002677:Chile; D002939:Ciprofloxacin / Q000494:pharmacology*; D003428:Cross Infection / Q000382:microbiology*; D018432:Drug Resistance, Multiple; D006801:Humans; D008826:Microbial Sensitivity Tests; D015337:Multicenter Studies as Topic; D018440:beta-Lactam Resistance; D047090:beta-Lactams
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D047090:beta-Lactams; D002939:Ciprofloxacin; D000583:Amikacin