Various blood parameters in commercial hens acutely and chronically infected with Mycoplasma gallisepticum and Mycoplasma synoviae.
Two trials were conducted to study the effects of acute (Trial 1) and chronic (Trial 2) mycoplasma infections on differential leukocyte counts in chickens. The trials initially included either 20 (Trial 1) or 40 (Trial 2) 6-wk-old commercial leghorn chickens negative for antibodies to Mycoplasma gallisepticum (MG) and Mycoplasma synoviae (MS). Chickens were inoculated with F strain MG (FMG), MS (WVU 1853), or both. One group of chickens remained uninoculated and served as a negative control for both trials. Chickens were housed in fiberglass isolation units from 6 to 10 wk (Trial 1) or 6 to 70 wk of age (Trial 2). Differential leukocyte counts were examined from 6 to 10 wk (Trial 1) or 66 to 70 wk of age (Trial 2) in all chickens. Also, in Trial 2, packed cell volumes (PCVs) and plasma protein values were examined from 66 to 70 wk of age. In the acute study (Trial 1), differential leukocyte counts revealed statistically significant differences (P < 0.05) in heterophil, lymphocyte, monocyte, eosinophil, and basophil values among treatments. In general, the differential counts of FMG- and MS-infected birds were characterized by heterophilia, lymphopenia, monocytosis, eosinopenia, and basopenia. Histopathologic examination of the spleen, liver, kidney, and bone marrow revealed a high degree of lymphoid foci within the spleen and bone marrow of all infected chickens. In the chronic study (Trial 2), no statistically significant differences (P < 0.05) were observed in differential leukocyte counts, PCV, and plasma protein values among treatments. Histopathologic examination of spleen, liver, kidney, and bone marrow did not reveal any difference among treatments.
Branton
S L
SL
USDA, Agricultural Research Service, Mississippi State, Mississippi 39762, USA.
May
J D
JD
Lott
B D
BD
Maslin
W R
WR
D000208:Acute Disease; D000818:Animals; D001798:Blood Proteins / Q000032:analysis; D002645:Chickens; D002908:Chronic Disease; D005260:Female; D007958:Leukocyte Count; D007970:Leukopenia / Q000209:etiology / Q000662:veterinary; D018655:Lymphocyte Count; D009174:Mycoplasma / Q000145:classification; D009175:Mycoplasma Infections / Q000097:blood / Q000662:veterinary*; D011201:Poultry Diseases
D001798:Blood Proteins