Effects of cardioselective beta blockers on ventilation and gas exchange in patients with heart disease during ramp treadmill testing.
The effects of cardioselective beta blockade on ventilation and gas exchange were investigated in 12 male subjects with coronary artery disease during ramp treadmill testing. Patients were able to maintain much of their functional capacity as measured by oxygen consumption in the beta-blocked condition, and also maintained minute ventilation by increasing respiratory rate despite a decrease in tidal volume.
Foley
K O
KO
Department of Medicine, Wake Forest University, Winston-Salem, North Carolina 27109, USA.
Brubaker
P H
PH
Matrazzo
B
B
Berry
M J
MJ
Pribanich
S
S
Miller
H S
HS
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D003327:Coronary Disease / Q000188:drug therapy* / Q000503:physiopathology; D005080:Exercise Test; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008297:Male; D008875:Middle Aged; D011659:Pulmonary Gas Exchange / Q000187:drug effects*; D012123:Pulmonary Ventilation / Q000187:drug effects*
D000319:Adrenergic beta-Antagonists