Connection of pharmacokinetics and pharmacodynamics--how does it work?
The present article gives an introduction to the correlation between drug transports and drug action in a body system. Direct linked model uses the law of mass action to describe the PK/PD modelling. More complex models like indirect linked models are discussed.
Cawello
W
W
Schwarz Pharma AG, Monheim am Rhein, Germany.
D004305:Dose-Response Relationship, Drug; D015195:Drug Design; D004347:Drug Interactions; D006801:Humans; D008954:Models, Biological; D010599:Pharmacokinetics; D010600:Pharmacology / Q000639:trends*