title: [A case of lung abscess with elevated serum levers of sialyl Lewis X-i (SLX) and CA 19-9].
abstract: A case of lung abscess of the felt lower lobe in a 19-year-old woman with elevated serum levels of Sialyl Lewis X-i (SLX) and CA 19-9 is reported. Completing the lobectomy, serum SLX level returned to the normal range within a week postoperative day. Serum CA 19-9 level also decreased at half life of 2 weeks to the normal range within 6 weeks postoperative day. Laboratory examination demonstrated high levels of these antigens in abscess fluid. Histologically, the abscess was revealed to be associated with a markedly dilated bronchus with hyperplastic bronchial glands, and there was no evidence of malignancy. Immunohistochemical examinations using monoclonal antibodies against human SLX and CA 19-9 showed highly positive reaction with those antigens in both goblet cells in bronchial epithelia and the mucous cells in bronchial glands.
authors.affiliation: Department of Thoracic Surgery, Tohoku University, Sendai, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Suzuki
authors.forename: S
authors.initials: S
authors.lastname: Ono
authors.forename: T
authors.initials: T
authors.lastname: Tanita
authors.forename: T
authors.initials: T
authors.lastname: Suzuki
authors.forename: T
authors.initials: T
authors.lastname: Takahashi
authors.forename: S
authors.initials: S
authors.lastname: Fujimura
mesh_terms: D000328:Adult; D018395:CA-19-9 Antigen / Q000097:blood*; D005260:Female; D006801:Humans; D016256:Lewis X Antigen / Q000097:blood*; D008169:Lung Abscess / Q000276:immunology / Q000601:surgery*
chemical_list: D018395:CA-19-9 Antigen; D016256:Lewis X Antigen