[Contrast media-associated nephropathy--pathogenesis and prevention].
Contrast media-associated nephrotoxicity continues to be a relevant cause of acute renal failure, especially in patients with pre-existing renal insufficiency. Alterations in renal hemodynamics and direct tubular toxicity by contrast media are the primary factors believed to be responsible for contrast media-associated nephrotoxicity. We review recent insights into the pathogenesis of this complication and summarize prophylactic strategies focussing on hydration, vasoactive pharmacological agents, and prophylactic hemodialysis'.
Erley
C M
CM
Abteilung Innere Medizin III, Universität Tübingen.
Duda
S H
SH
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000517:prevention & control; D003287:Contrast Media / Q000009:adverse effects*; D005919:Glomerular Filtration Rate / Q000187:drug effects; D006801:Humans; D007668:Kidney / Q000098:blood supply; D007677:Kidney Function Tests; D007684:Kidney Tubules / Q000187:drug effects; D012039:Regional Blood Flow / Q000187:drug effects; D006435:Renal Dialysis; D012307:Risk Factors; D013806:Theophylline / Q000008:administration & dosage; D014665:Vasodilator Agents / Q000008:administration & dosage
D003287:Contrast Media; D014665:Vasodilator Agents; D013806:Theophylline