title: Extralysosomal degradation of proteins.
abstract: Extralysosomal degradation of proteins is carried out by proteases complex (proteasomes), calcium dependent calpains, proteases of the rough endoplasmatic reticulum and proteases of the cellular membrane. It depends on a limited proteolysis and includes the main enzymatic proteins, hormones, growth factors and cytoskeletal proteins. Thus it plays an important regulatory role in the metabolism and formation of cellular structures.
authors.affiliation: Department of Vascular Surgery and Transplantology, Medical Academy of Bialystok.
authors.forename: M
authors.initials: M
authors.lastname: Gacko
mesh_terms: D000818:Animals; D002135:Calcium-Binding Proteins / Q000378:metabolism; D002154:Calpain / Q000378:metabolism; D002417:Cattle; D002451:Cell Compartmentation; D003546:Cysteine Endopeptidases / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism*; D006801:Humans; D009097:Multienzyme Complexes / Q000378:metabolism; D015388:Organelles / Q000201:enzymology; D046988:Proteasome Endopeptidase Complex; D011506:Proteins / Q000378:metabolism*; D051381:Rats
chemical_list: D002135:Calcium-Binding Proteins; D009097:Multienzyme Complexes; D011506:Proteins; C033668:calpastatin; D010450:Endopeptidases; D002154:Calpain; D003546:Cysteine Endopeptidases; D046988:Proteasome Endopeptidase Complex