Association between allele 1 of T102C polymorphism, 5-hydroxytryptamine 2a receptor gene and schizophrenia in Chinese males in Singapore.
The T102C polymorphism at the 5-hydroxytryptamine 2a receptor (5HTR2a) gene was studied in 101 Chinese male schizophrenics and 103 controls. Genotyping revealed a predominance of allele 1 among schizophrenics. This is in contrast to previous reports in Caucasians and Japanese which showed an association of allele 2 of this polymorphism with schizophrenia.
Tay
A H
AH
Institute of Molecular and Cell Biology, National University of Singapore, Republic of Singapore. mcbtayhn@nus.sg
Lim
L C
LC
Lee
W L
WL
Wong
K E
KE
Wong
L Y
LY
Tsoi
W F
WF
D000483:Alleles; D044466:Asian People / Q000235:genetics*; D005787:Gene Frequency; D005796:Genes; D005838:Genotype; D006801:Humans; D015810:Linkage Disequilibrium; D008297:Male; D011110:Polymorphism, Genetic; D011985:Receptors, Serotonin / Q000235:genetics*; D012559:Schizophrenia / Q000453:epidemiology* / Q000235:genetics*; D012846:Singapore / Q000453:epidemiology
D011985:Receptors, Serotonin