[Intercorrelation of psychopathological, morphologic, neurophysiologic an psychometric parameters in schizophrenic patients].
The present study was designed to determine the intercorrelation between schizophrenic symptoms, brain morphology, electrophysiological and neuropsychological variables. 44 patients, who met ICD-10 criteria for schizophrenic disorder, were included. At baseline, after 3 and 6 weeks BPRS, CGI, psychometric measurements and QEEG/ERP were performed. A CT scan was performed only at the beginning of the study. Data were evaluated by a multivariate test for data with an inherent structure. One of the most interesting findings is a correlation between BPRS total score and theta EEG power at baseline as well as under treatment. In conclusion, the study suggests the usefulness of multimethodological approaches in order to optimise diagnostic procedures in schizophrenia.
Pester
U
U
Klinik für Psychiatrie, Psychotherapie und Psychosomatische Medizin, Otto-von-Guericke-Universität Magdeburg.
Schwarz
A
A
Lerche
J
J
Brosz
M
M
Kropf
S
S
Ulrich
S
S
Bogerts
B
B
Wurthmann
C
C
D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D004569:Electroencephalography; D004594:Electrophysiology; D005260:Female; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D011569:Psychiatric Status Rating Scales; D011594:Psychometrics; D012559:Schizophrenia / Q000000981:diagnostic imaging / Q000473:pathology* / Q000503:physiopathology*; D012565:Schizophrenic Psychology; D014057:Tomography, X-Ray Computed