Extralysosomal degradation of proteins.
Extralysosomal degradation of proteins is carried out by proteases complex (proteasomes), calcium dependent calpains, proteases of the rough endoplasmatic reticulum and proteases of the cellular membrane. It depends on a limited proteolysis and includes the main enzymatic proteins, hormones, growth factors and cytoskeletal proteins. Thus it plays an important regulatory role in the metabolism and formation of cellular structures.
Gacko
M
M
Department of Vascular Surgery and Transplantology, Medical Academy of Bialystok.
D000818:Animals; D002135:Calcium-Binding Proteins / Q000378:metabolism; D002154:Calpain / Q000378:metabolism; D002417:Cattle; D002451:Cell Compartmentation; D003546:Cysteine Endopeptidases / Q000378:metabolism; D010450:Endopeptidases / Q000378:metabolism*; D006801:Humans; D009097:Multienzyme Complexes / Q000378:metabolism; D015388:Organelles / Q000201:enzymology; D046988:Proteasome Endopeptidase Complex; D011506:Proteins / Q000378:metabolism*; D051381:Rats
D002135:Calcium-Binding Proteins; D009097:Multienzyme Complexes; D011506:Proteins; C033668:calpastatin; D010450:Endopeptidases; D002154:Calpain; D003546:Cysteine Endopeptidases; D046988:Proteasome Endopeptidase Complex