Penile calciphylaxis.
Calciphylaxis is a condition of cutaneous necrosis secondary to small- and medium-sized vessel calcification that may progress rapidly and is often fatal. Patients with end-stage renal disease and hyperparathyroidism are almost exclusively at risk. Only 1 case of penile involvement has been previously described. At our institution, a 56-year-old man with end-stage renal disease presented with penile calciphylaxis. The patient received a series of treatments including circumcision, partial penectomy, amputation of necrotic phalanges, and a subtotal parathyroidectomy after which the patient's parathyroid hormone level normalized and the disease progression abated.
Wood
J C
JC
Department of Urology, Tulane University School of Medicine, New Orleans, Louisiana 70112, USA.
Monga
M
M
Hellstrom
W J
WJ
D002114:Calcinosis / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010409:Penile Diseases / Q000473:pathology*