Angiotensin converting enzyme (ACE) inhibitors and their implications for the dental surgeon.
Angiotensin enzyme converting (ACE) inhibitors are a widely prescribed group of drugs used in the management of hypertension and heart failure. Several unwanted effects are associated with ACE inhibitors and this paper highlights those significant to the dental surgeon. Of particular concern is the problem of angioedema, which can be life threatening. Three case reports are presented that illustrate this problem and the management is discussed.
Seymour
R A
RA
Department of Restorative Dentistry, Dental School, University of Newcastle upon Tyne.
Thomason
J M
JM
Nolan
A
A
D000799:Angioedema / Q000139:chemically induced* / Q000188:drug therapy; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D000959:Antihypertensive Agents / Q000009:adverse effects*; D005145:Face; D005260:Female; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D007818:Laryngeal Diseases / Q000139:chemically induced / Q000188:drug therapy; D017706:Lisinopril / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000139:chemically induced; D009060:Mouth Floor / Q000187:drug effects; D010608:Pharyngeal Diseases / Q000139:chemically induced / Q000188:drug therapy; D012008:Recurrence; D013651:Taste Disorders / Q000139:chemically induced*; D016593:Terfenadine / Q000627:therapeutic use; D014060:Tongue Diseases / Q000139:chemically induced* / Q000188:drug therapy
D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D006634:Histamine H1 Antagonists; D016593:Terfenadine; D017706:Lisinopril