title: POEMS syndrome in a 24-year-old man associated with vitamin B12 deficiency and a solitary lytic bone lesion.
abstract: We report one of the youngest cases of POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes), presenting in a 24-year-old man. A solitary lytic bone lesion and vitamin B12 deficiency were also found. We suggest that this syndrome be considered in cases of subacute polyneuropathy developing in young adults.
authors.affiliation: Division of Neurology, University of Toronto, Ontario, Canada.
authors.forename: P J
authors.initials: PJ
authors.lastname: Tuite
authors.forename: V
authors.initials: V
authors.lastname: Bril
mesh_terms: D000077:Acetabulum / Q000528:radiation effects; D000328:Adult; D001706:Biopsy; D001847:Bone Diseases / Q000150:complications* / Q000532:radiotherapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D009431:Neural Conduction; D016878:POEMS Syndrome / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D011241:Prednisone / Q000627:therapeutic use; D013497:Sural Nerve / Q000473:pathology; D014805:Vitamin B 12 / Q000627:therapeutic use; D014806:Vitamin B 12 Deficiency / Q000150:complications* / Q000188:drug therapy
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D003520:Cyclophosphamide; D014805:Vitamin B 12; D011241:Prednisone