Chronic hepatitis in an infant, in association with human herpesvirus-6 infection.
A 20-month-old boy was investigated for persistent liver dysfunction. Liver histologic findings showed chronic hepatitis. The presence of human herpesvirus-6 DNA in liver tissue was demonstrated both by in situ hybridization and by polymerase chain reaction. Human herpesvirus-6 may be a causative agent of chronic hepatitis in this case.
Tajiri
H
H
Department of Pediatrics, Faculty of Medicine, Osaka University, Japan.
Tanaka-Taya
K
K
Ozaki
Y
Y
Okada
S
S
Mushiake
S
S
Yamanishi
K
K
D001706:Biopsy; D015139:Blotting, Southern; D002908:Chronic Disease; D004279:DNA, Viral / Q000032:analysis*; D003937:Diagnosis, Differential; D005077:Exanthema Subitum / Q000150:complications*; D006525:Hepatitis, Viral, Human / Q000097:blood / Q000473:pathology / Q000821:virology*; D015654:Herpesvirus 6, Human / Q000235:genetics*; D006801:Humans; D017403:In Situ Hybridization; D007223:Infant; D007963:Leukocytes, Mononuclear / Q000821:virology*; D008297:Male; D016133:Polymerase Chain Reaction
D004279:DNA, Viral