title: Cyfra 21-1 and TPA as markers in malignant mesothelioma.
abstract: BACKGROUND
  Serum concentrations of CEA and Cyfra were compared in patients with mesothelioma.
  
  
  METHODS
  Serum levels of patients were analysed for prognosis of survival and follow up of disease.
  
  
  RESULTS
  Cyfra 21-1 and TPA have significant prognostic value for survival.
  
  
  CONCLUSIONS
  Assays measuring CK19 fragments seem to be good markers in the management of patients with malignant mesothelioma.
authors.affiliation: Department of Clinical Chemistry, The Netherlands Cancer Institute (Antoni van Leeuwenhoek Huis), Amsterdam, The Netherlands.
authors.forename: J M
authors.initials: JM
authors.lastname: Bonfrer
authors.forename: J H
authors.initials: JH
authors.lastname: Schouwink
authors.forename: C M
authors.initials: CM
authors.lastname: Korse
authors.forename: P
authors.initials: P
authors.lastname: Baas
mesh_terms: D000951:Antigens, Neoplasm / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D006801:Humans; D053539:Keratin-19; D007633:Keratins; D008654:Mesothelioma / Q000097:blood* / Q000401:mortality; D015996:Survival Rate; D019396:Tissue Polypeptide Antigen / Q000097:blood*
chemical_list: D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D053539:Keratin-19; D019396:Tissue Polypeptide Antigen; C102012:antigen CYFRA21.1; D007633:Keratins