title: Scanning force microscopy under aqueous solutions.
abstract: Merely ten years after its invention, the scanning force microscope is becoming a powerful method to investigate the structure and dynamics of biological molecules under aqueous environments. From the visualization of transcription in real time to the mechanical manipulation of individual proteins, the advances made during the past year open up a vast number of exciting applications of this technique in biology.
authors.affiliation: Howard Hughes Medical Institute, Chemistry Department, University of Oregon, Eugene 97403, USA. carlos@alice.uoregon.edu
authors.forename: C
authors.initials: C
authors.lastname: Bustamante
authors.forename: C
authors.initials: C
authors.lastname: Rivetti
authors.forename: D J
authors.initials: DJ
authors.lastname: Keller
mesh_terms: D064211:Connectin; D012321:DNA-Directed RNA Polymerases / Q000737:chemistry; D008565:Membrane Proteins / Q000737:chemistry*; D018625:Microscopy, Atomic Force / Q000379:methods*; D008854:Microscopy, Electron; D009124:Muscle Proteins / Q000737:chemistry; D011487:Protein Conformation; D017510:Protein Folding; D011494:Protein Kinases / Q000737:chemistry; D006180:Proton-Translocating ATPases; D014158:Transcription, Genetic
chemical_list: D064211:Connectin; D008565:Membrane Proteins; D009124:Muscle Proteins; D011494:Protein Kinases; D012321:DNA-Directed RNA Polymerases; D006180:Proton-Translocating ATPases