Management of the fetus with a correctable malformation in Paris maternity units: evolution 1985-1994.
OBJECTIVE
To analyze the evolution of the management of delivery and neonatal care in a population of children with correctable malformations born in Parisian maternity hospitals during the period 1985-1994.


METHODS
Data were collected by the Paris Registry of Congenital Anomalies from 400,000 births recorded in Parisian maternity hospitals over a 10-year period. Chromosomal anomalies were excluded. The evolution between the first period (1985-1989) and the second (1990-1994) was analyzed for the following indicators in the management of liveborn children: place of delivery; frequency of prenatal diagnosis; transfer to intensive care units, and mortality.


RESULTS
More than 60% of the births of malformed children took place in public maternity hospitals where better management is offered. Most of them were prenatally diagnosed, except for esophageal and anorectal atresia for which the rate of prenatal diagnosis was low. For malformations with poor prognoses (diaphragmatic and abdominal wall anomalies), the rate of deliveries in public maternity hospitals reached about 90%, mostly in those with intensive care units. The evolution between the two periods was characterized by a quicker transfer to intensive care units, during the first day of life for most cases. Lethality during the first day, which was already low during the first period, decreased further. The early neonatal mortality rate decreased for cardiac anomalies, but not significantly. The prognosis remained poor for diaphragmatic anomalies: 49% of liveborn children died during the first week of life.
De Vigan
C
C
Registre des Malformations Congénitales de Paris, INSERM U149, France.
Goujard
J
J
Vodovar
V
V
Uzan
S
S
D000009:Abdominal Muscles / Q000002:abnormalities; D000013:Congenital Abnormalities / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D003964:Diaphragm / Q000002:abnormalities; D004933:Esophageal Atresia / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D005260:Female; D006330:Heart Defects, Congenital / Q000175:diagnosis / Q000401:mortality / Q000628:therapy; D006801:Humans; D007226:Infant Mortality; D007231:Infant, Newborn; D015931:Intensive Care, Neonatal; D009775:Obstetrics and Gynecology Department, Hospital; D010297:Paris; D011247:Pregnancy; D011256:Pregnancy Outcome; D011296:Prenatal Diagnosis; D011379:Prognosis; D012007:Rectum / Q000002:abnormalities; D014524:Urethral Obstruction / Q000175:diagnosis / Q000401:mortality / Q000628:therapy