Capillary electrophoresis for pharmacokinetic studies.
Different analytical techniques involving capillary electrophoresis for the determination of drugs and metabolites in biological fluids are described. Pharmacokinetic studies carried out using capillary electrophoresis are presented, as well as the in vitro metabolism investigations. The advantages and the limitations of capillary electrophoresis for pharmacokinetic studies are discussed.
Levêque
D
D
Laboratory of Pharmacokinetics, Institute of Bacteriology, Strasbourg, France.
Gailion-Renault
C
C
Monteil
H
H
Jehl
F
F
D000818:Animals; D001826:Body Fluids / Q000737:chemistry; D019075:Electrophoresis, Capillary; D006801:Humans; D004364:Pharmaceutical Preparations / Q000032:analysis* / Q000378:metabolism; D010599:Pharmacokinetics
D004364:Pharmaceutical Preparations