Schizophrenia and disordered neural circuitry.
The knowledge of how alterations in neural circuitry relate to the symptoms of schizophrenia may depend on our ability to disentangle a complex cascade of pathological events that affect multiple brain regions. Recent progress in Alzheimer's disease research may provide several useful guiding principles in this pursuit.
Lewis
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Western Psychiatric Institute and Clinic, University of Pittsburgh, PA 15213-2593, USA.
D000544:Alzheimer Disease / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology; D001931:Brain Mapping; D006801:Humans; D009415:Nerve Net / Q000473:pathology / Q000503:physiopathology*; D012559:Schizophrenia / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology*; D012565:Schizophrenic Psychology