Hepatitis B and C virus infections in Turkish children with haemophilia.
We examined 41 Turkish children with haemophilia for evidence of hepatitis B virus (HBV) and hepatitis C virus (HCV) infections using the enzyme-linked immunosorbent assay (ELISA). Hepatitis B surface antigen was found to be positive in 11 patients (26.8%) and HCV-specific antibody (anti-HCV) was detected in 10 (24.4%) patients. There was a close relationship of the number of transfusions of blood plasma to the presence of HCV specific antibody, but not to the serum markers of HBV infection. In countries where HBV infection is commonly seen and problems in transfusion practice continue, as in Turkey, children with haemophilia are at greater risk for HBV and HCV infections.
Kocabaş
E
E
Department of Paediatric Infection, Cukurova University, Faculty of Medicine, Balcali, Adana, Turkey.
Aksaray
N
N
Alhan
E
E
Yarkin
F
F
Köksal
F
F
Kilinç
Y
Y
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D006467:Hemophilia A / Q000097:blood / Q000150:complications* / Q000821:virology; D006509:Hepatitis B / Q000097:blood / Q000150:complications*; D006514:Hepatitis B Surface Antigens; D006526:Hepatitis C / Q000097:blood / Q000150:complications*; D018936:Hepatitis C Antigens / Q000032:analysis; D006801:Humans; D007223:Infant; D008297:Male; D016036:Seroepidemiologic Studies; D014421:Turkey
D006514:Hepatitis B Surface Antigens; D018936:Hepatitis C Antigens