Evaluation of drug absorption after intrapulmonary administration using Xenopus pulmonary membranes: correlation with in vivo pulmonary absorption studies in rats.
Okumura
S
S
Department of Biopharmaceutics, Kyoto Pharmaceutical University, Japan.
Tanaka
H
H
Shinsako
K
K
Ito
M
M
Yamamoto
A
A
Muranishi
S
S
D000042:Absorption / Q000502:physiology; D000280:Administration, Inhalation; D000818:Animals; D002110:Caffeine / Q000493:pharmacokinetics; D002462:Cell Membrane / Q000378:metabolism; D000697:Central Nervous System Stimulants / Q000493:pharmacokinetics*; D005260:Female; D008297:Male; D051381:Rats; D015657:Respiratory Transport / Q000502:physiology*; D014982:Xenopus laevis
D000697:Central Nervous System Stimulants; D002110:Caffeine