Treatment of condylomata acuminata with oral isotretinoin.
OBJECTIVE
The aim of our study was to evaluate the efficacy and safety of oral isotretinoin in the treatment of condylomata acuminata.


METHODS
A total of 56 male patients with a history of condylomata acuminata refractory to at least 1 standard therapeutic regimen was treated orally with isotretinoin (1 mg./kg. daily) during a 3-month period.


RESULTS
At the end of treatment 21 of the 53 evaluated patients (39.6%) had complete response, 7 (13.2%) had partial response and 25 (47.1%) had no response. A statistically significant inverse relationship was found between age and area of treated lesions and response to medication. Two complete responders (9.5%) revealed recurrence during the 1-year followup.


CONCLUSIONS
Oral isotretinoin may be regarded as an effective, fairly well tolerated and noninvasive alternative form of therapy for immature and small condylomata acuminata.
Tsambaos
D
D
Department of Dermatology, University of Patras, Greece.
Georgiou
S
S
Monastirli
A
A
Sakkis
T
T
Sagriotis
A
A
Goerz
G
G
D000284:Administration, Oral; D000328:Adult; D003218:Condylomata Acuminata / Q000188:drug therapy*; D005832:Genital Diseases, Male / Q000188:drug therapy*; D006801:Humans; D015474:Isotretinoin / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged
D015474:Isotretinoin