title: The emerging role of CTLA-4 as an immune attenuator.
authors.affiliation: Gwen Knapp Center for Lupus and Immunology Research, Department of Medicine, University of Chicago, Illinois 60637, USA. craig@knapp.uchicago.edu
authors.forename: C B
authors.initials: CB
authors.lastname: Thompson
authors.forename: J P
authors.initials: JP
authors.lastname: Allison
mesh_terms: D000069594:Abatacept; D000595:Amino Acid Sequence; D000818:Animals; D000937:Antigen-Antibody Reactions; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000502:physiology*; D001327:Autoimmune Diseases / Q000209:etiology; D018122:B7-1 Antigen / Q000502:physiology; D001665:Binding Sites; D018106:CD28 Antigens / Q000502:physiology; D060908:CTLA-4 Antigen; D003593:Cytoplasm / Q000737:chemistry / Q000502:physiology; D006111:Graves Disease / Q000503:physiopathology; D006801:Humans; D018796:Immunoconjugates; D008213:Lymphocyte Activation; D008232:Lymphoproliferative Disorders / Q000209:etiology; D051379:Mice; D018345:Mice, Knockout; D008969:Molecular Sequence Data; D011971:Receptors, Immunologic / Q000502:physiology*; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D015703:Antigens, CD; D000943:Antigens, Differentiation; D018122:B7-1 Antigen; D018106:CD28 Antigens; D060908:CTLA-4 Antigen; C556706:CTLA4 protein, human; C556707:Ctla4 protein, mouse; D018796:Immunoconjugates; D011971:Receptors, Immunologic; D000069594:Abatacept