title: Oxidative damage and fragmentation of mitochondrial DNA in cellular apoptosis.
abstract: The molecular genetics and bioenergetics of oxidative damage, fragmentation, and fragility of mitochondrial DNA in cellular apoptosis is reviewed in connection with the "redox mechanism of ageing."
authors.affiliation: Department of Biomedical Chemistry, Faculty of Medicine, University of Nagoya, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Ozawa
mesh_terms: D000375:Aging; D000818:Animals; D017209:Apoptosis / Q000235:genetics*; D053938:DNA Fragmentation; D004272:DNA, Mitochondrial / Q000502:physiology*; D006801:Humans; D018384:Oxidative Stress
chemical_list: D004272:DNA, Mitochondrial