Acute renal failure due to indinavir crystalluria and nephrolithiasis: report of two cases.
Two patients with oliguric acute renal failure (ARF) attributed to crystalluria and nephrolithiasis with obstructive uropathy caused by the human immunodeficiency virus protease inhibitor indinavir are described. In both patients, ARF resolved with administration of intravenous fluids. One patient required urologic intervention to relieve bilateral ureteral obstruction.
Berns
J S
JS
Department of Medicine, Allegheny University Hospitals, Graduate, Philadelphia, PA 19146, USA.
Cohen
R M
RM
Silverman
M
M
Turner
J
J
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000628:therapy / Q000652:urine; D000328:Adult; D003460:Crystallization; D005440:Fluid Therapy; D015658:HIV Infections / Q000188:drug therapy*; D017320:HIV Protease Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D019469:Indinavir / Q000009:adverse effects* / Q000627:therapeutic use; D007669:Kidney Calculi / Q000139:chemically induced* / Q000628:therapy / Q000652:urine; D008297:Male
D017320:HIV Protease Inhibitors; D019469:Indinavir