[Mycobacterial antigens and antitubercular antibodies in patients with tuberculosis salpingo-oophoritis].
Sixty two and 59 patients with tuberculous and nontuberculous salpingo-oophoritis, respectively, and 30 healthy females were examined. It was found that indirect solid-phase enzyme immunoassay (EIA) using ultrasonography of Mycobacterium tuberculosis H37Rv could detect antituberculosis antibodies in 66.7% of patients with tuberculous salpingo-oophoritis, and in 10% of healthy females. That using the antigen isolated from the cell wall extract of M. tuberculosis (whose molecular weight was 38 - 42 kD) could reveal them in 70.2, 4.3%, and 6.7%, respectively. After dissociation of immune complexes, EIA inhibition using affinity-purified antimycobacterial antisera displayed mycobacterial antigens in 75.0 and 4.3% of patients with tuberculous and nontuberculous salpingo-oophoritis, respectively, and in none healthy female. Thus, the detection of mycobacterial antigens and antituberculosis antibody may be successfully used in the complex diagnosis of tuberculosis of the female genitals.
Bazarova
A B
AB
Central NII of Tuberculosis RAMN, Moscow.
Baenskií
A V
AV
Kulikovskaia
N V
NV
Litvinov
V I
VI
D000290:Adnexa Uteri / Q000382:microbiology; D000328:Adult; D000907:Antibodies, Bacterial / Q000032:analysis*; D000942:Antigens, Bacterial / Q000032:analysis*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006801:Humans; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000276:immunology*; D009869:Oophoritis / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology*; D012488:Salpingitis / Q000175:diagnosis / Q000276:immunology / Q000382:microbiology*; D014373:Tuberculin / Q000032:analysis; D014376:Tuberculosis / Q000150:complications / Q000175:diagnosis / Q000276:immunology*
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D014373:Tuberculin