title: Efficacy and tolerance of 400 MG bezafibrate in diabetic and hyperlipidaemic patients.
abstract: The authors report the results of an open clinical study using 400 mg Bezafibrate once a day. Among 25 diabetic patients (type II.) underwent a 4 weeks period with nutritional advice. Average changes from inclusion levels were -24% for total cholesterol, -56% for triglicerides, +11.9% for HDL-cholesterol, -19% for plama fibrinogen. In conclusion, bezafibrate at a daily dose of 400 mg had significant lipid-modifying properties but also exhibited a beneficial effect on other related risk factors such as fibrinogen reduction.
authors.affiliation: II.nd Department of Internal Medicine, University Medical School Pécs, Hungary.
authors.forename: J
authors.initials: J
authors.lastname: Lakatos
authors.forename: M
authors.initials: M
authors.lastname: Molnár
authors.forename: K
authors.initials: K
authors.lastname: Tóth
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001629:Bezafibrate / Q000009:adverse effects / Q000627:therapeutic use*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications*; D005260:Female; D006801:Humans; D006949:Hyperlipidemias / Q000097:blood* / Q000188:drug therapy*; D000960:Hypolipidemic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
chemical_list: D000960:Hypolipidemic Agents; D001629:Bezafibrate