[Antioncogenes--tumor suppression genes].
Recent knowledge about biological role of tumor suppressor genes and their products: RB1, p53, WT1, DCC, APC/FAP, NF1, NF2, VHL, MCC and MTS1 is presented. The main approaches of these agents as physiological regulators of cell growth and proliferation are discussed. Views on the tumor suppressor genes involvement in the development of inherited and sporadic forms of cancer have been reviewed.
Berbeć
H
H
Katedra i Zakład Chemii Fizjologicznej Akademii Medycznej w Lublinie.
D000818:Animals; D002455:Cell Division / Q000502:physiology; D016147:Genes, Tumor Suppressor / Q000502:physiology*; D006801:Humans; D009369:Neoplasms / Q000503:physiopathology