title: Clinical aspects and surgical treatment of hyperadrenocorticism in the domestic ferret: 94 cases (1994-1996).
abstract: The signalment, clinical findings, laboratory values, and histopathological results of 96 ferrets with signs (i.e., bilaterally symmetrical alopecia, return to male sexual behavior, or an enlarged vulva) suggestive of hyperadrenocorticism were evaluated retrospectively. Of these 96 ferrets, 94 (98%) were diagnosed with hyperadrenocorticism histologically. Treatment consisted of unilateral adrenalectomy for unilateral tumors (84%) and subtotal bilateral adrenalectomy for bilateral adrenal tumors (16%). The histopathological diagnosis included nodular hyperplasia (56%), adrenocortical carcinoma (26%), and adrenocortical adenoma (16%). Common concurrent diseases included splenomegaly (87%), islet-cell tumor (27%), and cardiomyopathy (10%).
authors.affiliation: Potomac Animal Hospital, Maryland 20854, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Weiss
authors.forename: M V
authors.initials: MV
authors.lastname: Scott
mesh_terms: D000236:Adenoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary; D000302:Adrenal Cortex / Q000378:metabolism / Q000473:pathology* / Q000601:surgery*; D000306:Adrenal Cortex Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary; D018268:Adrenocortical Carcinoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary; D000308:Adrenocortical Hyperfunction / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D000410:Alanine Transaminase / Q000097:blood; D000505:Alopecia / Q000473:pathology / Q000503:physiopathology / Q000662:veterinary; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001786:Blood Glucose / Q000032:analysis; D001806:Blood Urea Nitrogen; D002118:Calcium / Q000097:blood; D003404:Creatinine / Q000097:blood; D005260:Female; D005289:Ferrets; D006400:Hematocrit; D007958:Leukocyte Count; D008297:Male; D010758:Phosphorus / Q000097:blood; D012189:Retrospective Studies; D012709:Serum Albumin / Q000032:analysis; D012726:Sexual Behavior, Animal / Q000502:physiology
chemical_list: D001786:Blood Glucose; D012709:Serum Albumin; D010758:Phosphorus; D003404:Creatinine; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D002118:Calcium