[A case of lung abscess with elevated serum levers of sialyl Lewis X-i (SLX) and CA 19-9].
A case of lung abscess of the felt lower lobe in a 19-year-old woman with elevated serum levels of Sialyl Lewis X-i (SLX) and CA 19-9 is reported. Completing the lobectomy, serum SLX level returned to the normal range within a week postoperative day. Serum CA 19-9 level also decreased at half life of 2 weeks to the normal range within 6 weeks postoperative day. Laboratory examination demonstrated high levels of these antigens in abscess fluid. Histologically, the abscess was revealed to be associated with a markedly dilated bronchus with hyperplastic bronchial glands, and there was no evidence of malignancy. Immunohistochemical examinations using monoclonal antibodies against human SLX and CA 19-9 showed highly positive reaction with those antigens in both goblet cells in bronchial epithelia and the mucous cells in bronchial glands.
Suzuki
S
S
Department of Thoracic Surgery, Tohoku University, Sendai, Japan.
Ono
S
S
Tanita
T
T
Suzuki
T
T
Takahashi
T
T
Fujimura
S
S
D000328:Adult; D018395:CA-19-9 Antigen / Q000097:blood*; D005260:Female; D006801:Humans; D016256:Lewis X Antigen / Q000097:blood*; D008169:Lung Abscess / Q000276:immunology / Q000601:surgery*
D018395:CA-19-9 Antigen; D016256:Lewis X Antigen