title: Dioxin is a promoter blocker, a promoter, and a net anticarcinogen.
abstract: An ad hoc panel of dioxin experts convened by EPA's Science Advisory Board found the Agency's claim of cancer causation by dioxin unacceptable. This paper uses the very same two studies [Fingerhut (NIOSH) and Kociba] EPA relied upon to test the observations made in an unused third study [Bertazzi] to conclude that dioxin is (1) a promoter blocker of certain cancers, including all the cancers Agency scientists claimed dioxin promoted; (2) a promoter of some other cancers that EPA scientists failed to identify; and (3) a net anticarcinogen. Three independent total tumor reductions provide evidence of both cancer prevention and quantifiable risk reductions tied to specific dioxin levels. The author indirectly suggests a general cancer prevention treatment, even for cancers already initiated.
authors.forename: G
authors.initials: G
authors.lastname: Kayajanian
mesh_terms: D016588:Anticarcinogenic Agents / Q000633:toxicity*; D002273:Carcinogens / Q000037:antagonists & inhibitors; D004147:Dioxins / Q000627:therapeutic use / Q000633:toxicity*; D006801:Humans; D007558:Italy / Q000453:epidemiology; D009369:Neoplasms / Q000139:chemically induced* / Q000453:epidemiology / Q000517:prevention & control; D014481:United States; D014484:United States Environmental Protection Agency
chemical_list: D016588:Anticarcinogenic Agents; D002273:Carcinogens; D004147:Dioxins