Cytogenetic effects of 935.2-MHz (GSM) microwaves alone and in combination with mitomycin C.
This paper focuses on the genetic effects of microwaves from mobile communication frequencies (935.2 MHz) alone and in combination with a chemical DNA-damaging agent (mitomycin C). Three cytogenetic endpoints were investigated after in vitro exposure of human whole blood cells. These endpoints were the 'classical' chromosome aberration test, the sister chromatid exchange test and the alkaline comet assay. No direct cytogenetic effect was found. The combined exposure of the cells to the radiofrequency fields followed by their cultivation in the presence of mitomycin C revealed a very weak effect when compared to cells exposed to mitomycin C alone.
Maes
A
A
VITO, Environmental Toxicology, Mol, Belgium. maes@vito.be
Collier
M
M
Van Gorp
U
U
Vandoninck
S
S
Verschaeve
L
L
D002869:Chromosome Aberrations; D003582:Cytogenetics; D004247:DNA / Q000187:drug effects / Q000235:genetics / Q000528:radiation effects; D004249:DNA Damage; D004586:Electrophoresis / Q000379:methods; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D008297:Male; D008872:Microwaves / Q000009:adverse effects*; D016685:Mitomycin / Q000633:toxicity*; D009152:Mutagenicity Tests / Q000379:methods; D012854:Sister Chromatid Exchange / Q000187:drug effects / Q000528:radiation effects
D016685:Mitomycin; D004247:DNA