Movement-related cortical potentials and contingent negative variation in olivopontocerebellar atrophy.
Movement-related cortical potentials (MRCPs) and contingent negative variation (CNV) were recorded in 8 cases of olivopontocerebellar atrophy (OPCA) and 8 age-matched healthy controls. The amplitude of the negative slope (NS') was smaller in the OPCA group than in the healthy control group. The amplitude of late CNV was smaller in OPCA group than in the healthy control group. These abnormalities in MRCPs and CNV were improved by intravenous infusion of thyrotropin releasing hormone.
Oishi
M
M
Department of Neurology, Nihon University School of Medicine, Tokyo, Japan.
Mochizuki
Y
Y
Takasu
T
T
D000368:Aged; D016022:Case-Control Studies; D004569:Electroencephalography; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009068:Movement; D009849:Olivopontocerebellar Atrophies / Q000188:drug therapy* / Q000503:physiopathology*; D018709:Statistics, Nonparametric; D013973:Thyrotropin-Releasing Hormone / Q000627:therapeutic use*
D013973:Thyrotropin-Releasing Hormone