title: Alanine scan mutagenesis of chemokines.
authors.affiliation: Department of Immunology, Berlex Biosciences, Richmond, California 94804, USA.
authors.forename: J
authors.initials: J
authors.lastname: Hesselgesser
authors.forename: R
authors.initials: R
authors.lastname: Horuk
mesh_terms: D000409:Alanine / Q000235:genetics*; D000818:Animals; D000953:Antigens, Protozoan; D001667:Binding, Competitive; D002352:Carrier Proteins / Q000378:metabolism; D002478:Cells, Cultured; D054360:Chemokine CXCL1; D018925:Chemokines / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism; D019743:Chemokines, CXC; D002630:Chemotactic Factors / Q000235:genetics* / Q000378:metabolism / Q000494:pharmacology; D004912:Erythrocytes / Q000469:parasitology; D004926:Escherichia coli / Q000235:genetics; D015870:Gene Expression; D006133:Growth Substances / Q000235:genetics* / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins; D007668:Kidney; D019272:Leukocyte Elastase / Q000097:blood; D016297:Mutagenesis, Site-Directed; D009504:Neutrophils / Q000201:enzymology; D010455:Peptides / Q000138:chemical synthesis; D010957:Plasmids; D016790:Plasmodium knowlesi / Q000502:physiology; D015800:Protozoan Proteins; D011956:Receptors, Cell Surface / Q000378:metabolism; D018123:Receptors, Interleukin / Q000378:metabolism; D023063:Receptors, Interleukin-8B; D011994:Recombinant Proteins / Q000302:isolation & purification / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D000953:Antigens, Protozoan; C475829:CXCL1 protein, human; D002352:Carrier Proteins; D054360:Chemokine CXCL1; D018925:Chemokines; D019743:Chemokines, CXC; D002630:Chemotactic Factors; C066001:Duffy antigen binding protein, Plasmodium; D006133:Growth Substances; D036341:Intercellular Signaling Peptides and Proteins; D010455:Peptides; D015800:Protozoan Proteins; D011956:Receptors, Cell Surface; D018123:Receptors, Interleukin; D023063:Receptors, Interleukin-8B; D011994:Recombinant Proteins; D019272:Leukocyte Elastase; D000409:Alanine