title: The rare association of tetralogy of Fallot with hypertrophic cardiomyopathy. Report of 2 neonatal patients.
abstract: Although tetralogy of Fallot is commonly associated with other congenital heart defects, it is rarely found in conjunction with hypertrophic cardiomyopathy. We describe the cases of 2 neonates with this rare condition, both of whom required surgical intervention during infancy. Because hypertrophic cardiomyopathy is frequently familial, and tetralogy of Fallot is commonly found in patients diagnosed with chromosomal anomalies, we speculate about a possible genetic cause for this association.
authors.affiliation: Lillie Frank Abercrombie Section of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston 77030-2399, USA.
authors.forename: M B
authors.initials: MB
authors.lastname: Lewin
authors.forename: J A
authors.initials: JA
authors.lastname: Towbin
authors.forename: M K
authors.initials: MK
authors.lastname: Thapar
authors.forename: W J
authors.initials: WJ
authors.lastname: Dreyer
authors.forename: T F
authors.initials: TF
authors.lastname: Feltes
mesh_terms: D002312:Cardiomyopathy, Hypertrophic / Q000150:complications* / Q000235:genetics / Q000601:surgery; D002869:Chromosome Aberrations; D002878:Chromosomes, Human, Pair 1; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007621:Karyotyping; D008297:Male; D012307:Risk Factors; D013771:Tetralogy of Fallot / Q000150:complications* / Q000235:genetics / Q000601:surgery