title: Generating, partitioning, targeting and functioning of superoxide in mitochondria.
abstract: Recently, we proposed a hypothetical model of coexistence of "Reactive oxygen cycle" with Q cycle and H+ cycle in mitochondrial respiratory chain to combine both processes of univalent electron leak for production of superoxide and of proton leak across inner mitochondrial membrane. This review presents a more detailed description of this model and summaries the supporting experimental evidence obtained.
authors.affiliation: State Key Laboratory of Biomembrane and Membrane Biotechnology, Chinese Academy of Sciences, Beijing, China.
authors.forename: S S
authors.initials: SS
authors.lastname: Liu
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000378:metabolism; D019069:Cell Respiration; D006801:Humans; D008564:Membrane Potentials; D008928:Mitochondria / Q000378:metabolism*; D008954:Models, Biological; D011522:Protons; D017382:Reactive Oxygen Species; D013481:Superoxides / Q000378:metabolism*
chemical_list: D011522:Protons; D017382:Reactive Oxygen Species; D013481:Superoxides