title: Multiple intramedullary spinal sarcoidosis: case report.
abstract: BACKGROUND
  According to past reported cases, spinal intramedullary sarcoidosis has the radiologic characteristics of a single enhanced lesion with cord swelling. However, it is difficult to make a diagnosis using only radiologic examinations. Including our case, 20 cases have been reported of intramedullary spinal sarcoidosis. Only six cases were diagnosed as primary spinal sarcoidosis. We present a rare case of multiple spinal intramedullary sarcoidosis without cord swelling.
  
  
  METHODS
  This 63 year-old man was afflicted with progressive paraparesis and numbness of the lower extremities. Magnetic resonance imaging showed intramedullary lesions without cord swelling. The patient underwent biopsy for diagnosis and the specimen showed a noncaseating granuloma mainly composed of epitheloid cells. Postoperative corticosteroid therapy was effective and the lesion disappeared 1 month after the operation.
  
  
  CONCLUSIONS
  Biopsy is a less invasive method and is useful for early diagnosis. Early diagnosis is important for spinal sarcoidosis so that high-dose corticosteroid therapy can be commenced while the lesion still has a good chance of being successfully treated.
authors.affiliation: Department of Neurosurgery, Osaka Prefectural Hospital, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Chitoku
authors.forename: S
authors.initials: S
authors.lastname: Kawai
authors.forename: Y
authors.initials: Y
authors.lastname: Watabe
authors.forename: M
authors.initials: M
authors.lastname: Nishitani
authors.forename: K
authors.initials: K
authors.lastname: Fujimoto
authors.forename: H
authors.initials: H
authors.lastname: Otsuka
authors.forename: H
authors.initials: H
authors.lastname: Fushimi
authors.forename: K
authors.initials: K
authors.lastname: Kotoh
mesh_terms: D006801:Humans; D008297:Male; D008875:Middle Aged; D012507:Sarcoidosis; D013122:Spinal Diseases