The activation by magnesium treatment of anti-oxidants eliminating the oxygen free radicals in Drosophila melanogaster in vivo.
Drosophila melanogaster adults of the Oregon R and Canton S wild-type stocks were fed for 24 h with 0.10 M, 0.25 M and 0.50 M MgCl2 in 1 per cent sugar solution. This treatment resulted in a significant increase (10-50 per cent) in the activities of the enzymes superoxide dismutase (SOD) and catalase as well as in the concentration of the non-enzymatic antioxidant glutathione (GSH). The increased activities could be due to the increased synthesis caused by the Mg treatment.
Matkovics
B
B
Attila József University, Isotope Laboratory, Szeged, Hungary.
Kiss
I
I
Kiss
S A
SA
D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D002374:Catalase / Q000187:drug effects; D004032:Diet; D004331:Drosophila melanogaster / Q000187:drug effects / Q000201:enzymology / Q000378:metabolism*; D005260:Female; D005978:Glutathione / Q000187:drug effects / Q000378:metabolism; D017665:Hydroxyl Radical / Q000378:metabolism; D015227:Lipid Peroxidation / Q000187:drug effects; D008274:Magnesium / Q000008:administration & dosage*; D008297:Male; D017382:Reactive Oxygen Species / Q000378:metabolism*; D013482:Superoxide Dismutase / Q000187:drug effects
D000975:Antioxidants; D017382:Reactive Oxygen Species; D017665:Hydroxyl Radical; D002374:Catalase; D013482:Superoxide Dismutase; D005978:Glutathione; D008274:Magnesium