Fruiting-inducing activity and antifungal properties of lipid components in members of Annelida.
Fruiting-inducing activity and antifungal properties of lipid components in the phylum Annelida were examined. Some amphoteric cerebrosides carrying a phosphocholine group showed fruiting-inducing activity on Schizophyllum commune, and one of them possessed activity comparable to that of Sch II, the most potent substance known. Furthermore, alkyl lysophosphatidylcholines were found to have an inhibitory effect on the growth of phytopathogenic fungi, Alternaria kikuchiana and Phomopsis mali. The relationship between structure and biological activities is discussed.
Tanaka
R
R
Faculty of Pharmaceutical Sciences, Setsunan University, Osaka, Japan.
Ishizaki
H
H
Kawano
S
S
Okuda
H
H
Miyahara
K
K
Noda
N
N
D000528:Alternaria / Q000187:drug effects*; D000818:Animals; D000845:Annelida / Q000378:metabolism*; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002554:Cerebrosides / Q000302:isolation & purification / Q000494:pharmacology; D008244:Lysophosphatidylcholines / Q000494:pharmacology; D010743:Phospholipids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D012567:Schizophyllum / Q000187:drug effects*; D013329:Structure-Activity Relationship
D000935:Antifungal Agents; D002554:Cerebrosides; D008244:Lysophosphatidylcholines; D010743:Phospholipids