title: Pathophysiology and management of portal hypertension. 1: Variceal haemorrhage.
abstract: Portal hypertension occurs secondary to a combination of increased resistance to portal venous flow and increased splanchnic inflow to the portal venous system. The main clinical complication is gastrooesophageal haemorrhage from which mortality remains high at approximately 40%.
authors.affiliation: Department of Medicine, Royal Infirmary of Edinburgh.
authors.forename: A J
authors.initials: AJ
authors.lastname: Stanley
authors.forename: I A
authors.initials: IA
authors.lastname: Bouchier
authors.forename: P C
authors.initials: PC
authors.lastname: Hayes
mesh_terms: D004932:Esophageal and Gastric Varices / Q000503:physiopathology / Q000628:therapy*; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000628:therapy*; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications / Q000503:physiopathology* / Q000628:therapy*; D012008:Recurrence