title: Early gastric cancer and lymph node metastasis.
abstract: A total of 1,845 cases of gastric cancer have been resected in our hospital during the past 18 years. Of these, 764 cases (41.5%) were early gastric cancer. The rate of lymph node metastasis was 2% in early mucosal cancer and 19.4% in early submucosal cancer (p < 0.001). In the cases of early mucosal cancer, the rate of lymph node metastasis was 0.9% for the elevated type and 2.4% for the depressed type. In the cases of early submucosal cancer, the rate of lymph node metastasis was 25.3% for the elevated type and 17.3% for the depressed type. In the mucosal cancers the rate of lymph node metastasis was high in the 0-IIc and IIc + III macroscopic type, and in the poorly differentiated microscopic type. In the submucosal cancers the rate of lymph node metastasis was 40% in mucinous adenocarcinoma and 33% in papillary adenocarcinoma. There was no lymph node metastasis in any case of early gastric cancer smaller than 1 cm surface diameter.
authors.affiliation: Department of Gastroenterology, Kurume University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Koufuji
authors.forename: J
authors.initials: J
authors.lastname: Takeda
authors.forename: A
authors.initials: A
authors.lastname: Toyonaga
authors.forename: S
authors.initials: S
authors.lastname: Yoshihara
authors.forename: Y
authors.initials: Y
authors.lastname: Tanaka
authors.forename: J
authors.initials: J
authors.lastname: Ohta
authors.forename: K
authors.initials: K
authors.lastname: Aoyagi
authors.forename: S
authors.initials: S
authors.lastname: Yano
authors.forename: I
authors.initials: I
authors.lastname: Kodama
authors.forename: K
authors.initials: K
authors.lastname: Shirouzu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013274:Stomach Neoplasms / Q000473:pathology*