Identification of superoxide dismutase activity in Borrelia burgdorferi.
Infective and noninfective strains of Borrelia burgdorferi, along with Borrelia afzelii and Borrelia garinii, possessed a single iron-containing superoxide dismutase (SOD). None of the Lyme disease spirochetes tested possessed catalase or peroxidase activities. The borrelial SOD was not inducible by growth with increased oxygen concentrations and thus appeared to be produced constitutively.
Whitehouse
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CA
Department of Microbiology and Immunology, University of Louisville School of Medicine, Kentucky 40292, USA.
Williams
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LR
Austin
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D015748:Borrelia burgdorferi Group / Q000201:enzymology*; D010100:Oxygen / Q000494:pharmacology; D010544:Peroxidases / Q000378:metabolism; D012966:Sodium Cyanide / Q000494:pharmacology; D013482:Superoxide Dismutase / Q000378:metabolism*
D010544:Peroxidases; D013482:Superoxide Dismutase; D012966:Sodium Cyanide; D010100:Oxygen