The selective recognition of antibody IgY for digestive system cancers.
Biological methods for cancer therapies are very important. A small and efficient target carrier is the key component for anti-cancer drugs. In our laboratory, the antibody IgY was extracted from egg yolk of a SPF hen. The SPF hen was immunized with an antigene of P110 protein which was purified from human stomach cancer MGC-803 cells. Results indicated that the antibody IgY can specifically recognize gastrointestinal system cancers. It may become an important carrier for antitumorigenic drugs.
Yang
J
J
Institute of Genetics, Chinese Academy of Sciences, Beijing, China.
Jin
Z
Z
Yu
Q
Q
Yang
T
T
Wang
H
H
Liu
L
L
D000230:Adenocarcinoma / Q000276:immunology*; D000818:Animals; D000912:Antibodies, Neoplasm / Q000276:immunology*; D000951:Antigens, Neoplasm / Q000032:analysis / Q000276:immunology; D015153:Blotting, Western; D002645:Chickens; D004591:Electrophoresis, Polyacrylamide Gel; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology* / Q000302:isolation & purification; D011817:Rabbits; D013274:Stomach Neoplasms / Q000276:immunology*; D014407:Tumor Cells, Cultured
D000912:Antibodies, Neoplasm; D000951:Antigens, Neoplasm; C016512:IgY; D007136:Immunoglobulins