title: Primary low-grade T-helper cell testicular lymphoma.
abstract: Non-Hodgkin's lymphoma is the most common primary testicular neoplasm of older men but is rare in young men. The vast majority of primary testicular lymphomas are intermediate- to high-grade lymphomas. Peripheral T-cell lymphomas of the testes are rare; most are large cell lymphomas. We describe an unusual case of a primary small lymphocytic, CD4+, peripheral T-cell lymphoma that presented as a Staphylococcus aureus scrotal abscess in a 30-year-old male. Clonal rearrangement of the T-cell receptor beta gene was demonstrated by Southern analysis. To our knowledge, low-grade, peripheral T-cell lymphoma of the testes has not been previously reported.
authors.affiliation: Department of Laboratory Medicine, Geisinger Medical Center, Danville, MN, USA.
authors.forename: M K
authors.initials: MK
authors.lastname: Froberg
authors.forename: H
authors.initials: H
authors.lastname: Hamati
authors.forename: J A
authors.initials: JA
authors.lastname: Kant
authors.forename: K
authors.initials: K
authors.lastname: Addya
authors.forename: K E
authors.initials: KE
authors.lastname: Salhany
mesh_terms: D000328:Adult; D015139:Blotting, Southern; D017252:CD3 Complex / Q000032:analysis; D004273:DNA, Neoplasm / Q000235:genetics; D015333:Gene Rearrangement, beta-Chain T-Cell Antigen Receptor; D006801:Humans; D007124:Immunoenzyme Techniques; D015850:Interleukin-6 / Q000032:analysis; D016399:Lymphoma, T-Cell / Q000235:genetics / Q000473:pathology*; D008297:Male; D016176:T-Lymphocyte Subsets; D006377:T-Lymphocytes, Helper-Inducer / Q000473:pathology*; D013736:Testicular Neoplasms / Q000235:genetics / Q000473:pathology*
chemical_list: D017252:CD3 Complex; D004273:DNA, Neoplasm; D015850:Interleukin-6