title: Tetracycline and niacinamide for the treatment of sterile pyogranuloma/granuloma syndrome in a dog.
abstract: A sterile pyogranuloma/granuloma syndrome in a dog is described. Diagnosis was based on cytological examinations of the skin and lymph nodes and histopathological examinations of the skin and nictitans. Although the condition initially was responsive to large doses of glucocorticoids, it subsequently was treated successfully with tetracycline and niacinamide. The excellent responses of this dog suggest that this drug combination may be a viable therapeutic option for dogs in which glucocorticoids cannot be used.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853-6401, USA.
authors.forename: E
authors.initials: E
authors.lastname: Rothstein
authors.forename: D W
authors.initials: DW
authors.lastname: Scott
authors.forename: R C
authors.initials: RC
authors.lastname: Riis
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001706:Biopsy / Q000379:methods / Q000662:veterinary; D004283:Dog Diseases / Q000188:drug therapy* / Q000473:pathology; D004285:Dogs; D004359:Drug Therapy, Combination; D006099:Granuloma / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D009536:Niacinamide / Q000627:therapeutic use*; D012867:Skin / Q000473:pathology; D012871:Skin Diseases / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D013577:Syndrome; D013752:Tetracycline / Q000627:therapeutic use*
chemical_list: D000900:Anti-Bacterial Agents; D009536:Niacinamide; D013752:Tetracycline