title: Remarkable inhibitory effects of hybrid liposomes on the growth of HL-60 cells coupled to induction of apoptosis.
abstract: The hybrid liposomes (90 mol% DMPC/10 mol% C12(EO)10 or C12(EO)12) have a highly inhibitory effect on the growth of tumor cells (HL-60). The induction of apoptosis by the hybrid liposomes in HL-60 cells was revealed on the basis of flow cytometry and DNA electrophoresis.
authors.affiliation: Kumamoto Institute of Technology, Japan.
authors.forename: C
authors.initials: C
authors.lastname: Imamura
authors.forename: Y
authors.initials: Y
authors.lastname: Kemura
authors.forename: Y
authors.initials: Y
authors.lastname: Matsumoto
authors.forename: R
authors.initials: R
authors.lastname: Ueoka
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000633:toxicity; D017209:Apoptosis / Q000187:drug effects*; D016923:Cell Death; D053938:DNA Fragmentation / Q000187:drug effects; D004134:Dimyristoylphosphatidylcholine; D004587:Electrophoresis, Agar Gel; D018922:HL-60 Cells; D006801:Humans; D008081:Liposomes / Q000737:chemistry / Q000494:pharmacology* / Q000633:toxicity; D000077423:Polidocanol; D011092:Polyethylene Glycols
chemical_list: D000970:Antineoplastic Agents; D008081:Liposomes; D000077423:Polidocanol; D011092:Polyethylene Glycols; D004134:Dimyristoylphosphatidylcholine