title: Molecular mechanisms of ligand binding and activation in alpha 1-adrenergic receptors.
authors.affiliation: Department of Molecular Cardiology, Cleveland Clinic Research Institute, Ohio 44195, USA.
authors.forename: D M
authors.initials: DM
authors.lastname: Perez
authors.forename: J
authors.initials: J
authors.lastname: Hwa
authors.forename: M M
authors.initials: MM
authors.lastname: Zhao
authors.forename: J
authors.initials: J
authors.lastname: Porter
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000378:metabolism* / Q000494:pharmacology*; D000317:Adrenergic alpha-Antagonists / Q000494:pharmacology; D019943:Amino Acid Substitution; D000818:Animals; D002396:Catechols / Q000378:metabolism; D004837:Epinephrine / Q000378:metabolism; D007295:Inositol Phosphates / Q000378:metabolism; D008024:Ligands; D016297:Mutagenesis, Site-Directed; D017354:Point Mutation; D011487:Protein Conformation; D018340:Receptors, Adrenergic, alpha-1 / Q000378:metabolism / Q000502:physiology*
chemical_list: D000316:Adrenergic alpha-Agonists; D000317:Adrenergic alpha-Antagonists; D002396:Catechols; D007295:Inositol Phosphates; D008024:Ligands; D018340:Receptors, Adrenergic, alpha-1; D004837:Epinephrine