title: Positron emission tomography: background, possibilities and perspectives in neuroscience.
abstract: Positron Emission Tomography (PET) is a method for determining biochemical and physiological processes in vivo in a quantitative way. This includes the measurement of the pharmacokinetics of labeled drugs and the measurement of the effects of drugs and/or therapy on metabolism. Also deviations of normal metabolism can be measured and insight in biological processes responsible for diseases can be obtained. To accomplish these measurements a multi-disciplinary team is necessary for the expertise in the fields of radionuclide production, radiochemistry, pharmacy, medicine, nuclear imaging and data analysis.
authors.affiliation: PET-Center, Groningen University Hospital, The Netherlands.
authors.forename: A M
authors.initials: AM
authors.lastname: Paans
mesh_terms: D017357:Cyclotrons; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D049673:History, 20th Century; D006801:Humans; D009462:Neurology / Q000379:methods*; D014055:Tomography, Emission-Computed / Q000266:history / Q000295:instrumentation
chemical_list: D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18