title: ICE: a novel and efficient method for isolation of chromosomal ends.
abstract: The linear chromosomal ends are usually unclonable by general methods due to a lack of restriction sites. We present a novel method, isolation of chromosomal ends (ICE), which has been developed for the efficient isolation of linear DNA ends.
authors.affiliation: Department of Life Science, Tokyo Institute of Technology, Yokohama, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Hatakeyama
authors.forename: F
authors.initials: F
authors.lastname: Ishikawa
mesh_terms: D002877:Chromosomes, Human; D004247:DNA / Q000302:isolation & purification*; D005821:Genetic Techniques; D006801:Humans; D011061:Poly A / Q000302:isolation & purification; D016615:Telomere
chemical_list: D011061:Poly A; C015465:poly(dA); D004247:DNA