title: Treatment of facial furrows and rhytides.
abstract: Many substances have historically been used to address facial soft tissue defects. Currently in the United States autologous fat and injectable bovine collagen are the most commonly utilized injectable fillers. Additionally, the judicious application of BOTOX in the upper face as well as neck has all but revolutionized the use of filling agents in these locales. While other agents are briefly mentioned, this is an in-depth review of the characteristics and application of autologous fat, bovine collagen.
authors.affiliation: Department of Medicine, UCLA School of Medicine, USA.
authors.forename: A W
authors.initials: AW
authors.lastname: Klein
authors.forename: P
authors.initials: P
authors.lastname: Wexler
authors.forename: A
authors.initials: A
authors.lastname: Carruthers
authors.forename: J
authors.initials: J
authors.lastname: Carruthers
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D002417:Cattle; D003094:Collagen / Q000008:administration & dosage*; D004954:Esthetics; D005260:Female; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D008875:Middle Aged; D015361:Rhytidoplasty / Q000379:methods*; D015595:Skin Aging / Q000187:drug effects; D016896:Treatment Outcome
chemical_list: D003094:Collagen