title: [Granulocyte function and lipid peroxidation in untreated patients with hyperlipoproteinemia].
abstract: The fatty acid composition in free fatty acid and phospholipid fraction of plasma in untreated mildly hyperlipidemic patients were determined. The general trend was an increase in saturation in both free and phospholipid fractions of plasma in patients compared with that of healthy controls. Furthermore, arachidonic acid, precursor of formation of prostaglandins and leukotrienes was detected in significantly lower amount in plasma of mildly and untreated hyperlipidemic patients. These fatty acid abnormalities were connected with the increased lipidperoxidation in plasma lipids and in both resting and stimulated granulocytes.
authors.affiliation: Debreceni Orvostudományi Egyetem 1. Belgyógyászati Klinika.
authors.forename: Z
authors.initials: Z
authors.lastname: Varga
authors.forename: G
authors.initials: G
authors.lastname: Paragh
authors.forename: I
authors.initials: I
authors.lastname: Kárpáti
authors.forename: I
authors.initials: I
authors.lastname: Seres
authors.forename: L
authors.initials: L
authors.lastname: Buris
authors.forename: G
authors.initials: G
authors.lastname: Kakuk
mesh_terms: D000328:Adult; D002784:Cholesterol / Q000097:blood; D005227:Fatty Acids / Q000097:blood*; D005260:Female; D006098:Granulocytes; D006801:Humans; D006951:Hyperlipoproteinemias / Q000097:blood*; D008054:Lipid Peroxides / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010743:Phospholipids / Q000097:blood; D014280:Triglycerides / Q000097:blood
chemical_list: D005227:Fatty Acids; D008054:Lipid Peroxides; D010743:Phospholipids; D014280:Triglycerides; D002784:Cholesterol