title: Monoamine oxidase genes polymorphisms and mood disorder.
abstract: We investigated a genetic association between mood disorders (bipolar and unipolar) and the alleles of monoamine oxidase (MAO) A and B (MAOA and MAOB). One hundred and twelve unrelated Japanese patients (60 bipolar, 52 unipolar) and 100 controls were genotyped for three markers of MAOA and for one marker of MAOB. No statistically significant difference in the distribution of the alleles existed between cases and controls. Therefore, our results did not support the involvement of the alleles at MAOA and MAOB in the etiology of mood disorder.
authors.affiliation: Department of Psychiatry, Kurihama National Hospital, Kanagawa, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Muramatsu
authors.forename: S
authors.initials: S
authors.lastname: Matsushita
authors.forename: S
authors.initials: S
authors.lastname: Kanba
authors.forename: S
authors.initials: S
authors.lastname: Higuchi
authors.forename: H
authors.initials: H
authors.lastname: Manki
authors.forename: E
authors.initials: E
authors.lastname: Suzuki
authors.forename: M
authors.initials: M
authors.lastname: Asai
mesh_terms: D000328:Adult; D005260:Female; D005796:Genes; D005819:Genetic Markers; D006801:Humans; D008297:Male; D008875:Middle Aged; D008995:Monoamine Oxidase / Q000235:genetics*; D019964:Mood Disorders / Q000201:enzymology* / Q000235:genetics*; D011110:Polymorphism, Genetic
chemical_list: D005819:Genetic Markers; D008995:Monoamine Oxidase