Symposium on rectal cancer: 2. Local recurrence after surgery for rectal cancer.
Local recurrence is a serious complication in patients with rectal cancer because of the frequency with which it occurs, its impact on quality of life and the fact that treatment is rarely successful. Although local recurrence rates varying from 4% to 51% have been reported, recent series have reported rates of less than 10%. Various factors may affect the rate of local recurrence, including the stage and location of the tumour. Other prognostic factors may be of importance, but it is controversial whether they are independent risk factors. Finally, there is mounting evidence that the local recurrence rate varies with the surgeon. Whether this is due to the surgical technique or surgical expertise is not clear, but randomized controlled trials addressing the issue of extent of resection are indicated in order to optimize surgical results.
McLeod
R S
RS
Department of Surgery, Mount Sinai Hospital, University of Toronto, Ont.
D006801:Humans; D015994:Incidence; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology / Q000209:etiology* / Q000517:prevention & control; D011379:Prognosis; D011788:Quality of Life; D012004:Rectal Neoplasms / Q000601:surgery*; D012307:Risk Factors; D016896:Treatment Outcome