Management of psoriasis with calcipotriol used as monotherapy.
BACKGROUND
The vitamin D analog calcipotriene/calcipotriol (Dovonex/Daivonex) offers advantages over other forms of topical therapy in some patients with psoriasis.


OBJECTIVE
We review the studies of the use of calcipotriol alone in the management of psoriasis.


METHODS
The literature concerning topical calcipotriol therapy was reviewed.


RESULTS
Calcipotriol compares well with other standard forms of topical therapy for psoriasis. Irritation of the skin may occur but is generally mild. Treatment can often be restarted after the irritation has cleared.


CONCLUSIONS
Treatment with calcipotriol ointment, cream, or solution is effective and safe in many patients with psoriasis.
Ramsay
C A
CA
University of Toronto, Ontario, Canada.
D000279:Administration, Cutaneous; D002117:Calcitriol / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D007509:Irritants / Q000009:adverse effects; D009824:Ointments; D011565:Psoriasis / Q000188:drug therapy*; D016032:Randomized Controlled Trials as Topic; D012449:Safety; D012996:Solutions
D003879:Dermatologic Agents; D007509:Irritants; D009824:Ointments; D012996:Solutions; C055085:calcipotriene; D002117:Calcitriol