title: Temporolimbic or transcallosal connections: where is the primary lesion in schizophrenia and what is its nature?
abstract: A critique of the article by Bogerts on the temporolimbic system theory is presented. Schizophrenia is conceived as arising as a component of the diversity of interhemisphric (callosal) connectivity associated with the evolution of language, a process that occurred through a genetic change (the speciation event) that allowed the hemispheres to develop with a degree of independence. Language and psychosis thus have a common evolutionary origin. The anatomical changes can be considered as a boundary component of the anatomical variation that is characteristic of the species.
authors.affiliation: Dept. of Psychiatry, University of Oxford, Warneford Hospital, England.
authors.forename: T J
authors.initials: TJ
authors.lastname: Crow
mesh_terms: D005075:Biological Evolution; D001931:Brain Mapping; D003337:Corpus Callosum / Q000473:pathology / Q000503:physiopathology*; D004292:Dominance, Cerebral / Q000502:physiology*; D006801:Humans; D008032:Limbic System / Q000473:pathology / Q000503:physiopathology*; D009434:Neural Pathways / Q000473:pathology / Q000503:physiopathology; D012559:Schizophrenia / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology*; D012565:Schizophrenic Psychology; D013702:Temporal Lobe / Q000473:pathology / Q000503:physiopathology*