[Precocious menopause after antimitotic therapy. Is in vitro fertilization with oocyte donation the only appropriate response?].
Advances in antimitotic treatments have improved the prognosis of cancer in young subjects. The resulting increase in life expectancy raises the question of the subject's future fertility, a question that should be posed before beginning any anticancer therapy which could lead to a gonadal failure. If oocyte donation remains the alternative indication proposed for these patients desiring a child, it is important to assess the tissue alterations in the uterus, to verify its vascularization under suitable treatment and appreciate the other alternative directions.
Letur-Könirsch
H
H
CECOS Necker, Groupe hospitalier Necker Enfants-Malades, Paris.
Guis
F
F
Duymes
M
M
Alnot
M O
MO
Fernandez
H
H
D000970:Antineoplastic Agents / Q000009:adverse effects*; D015914:Estrogen Replacement Therapy; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000139:chemically induced* / Q000628:therapy*; D008017:Life Expectancy; D008594:Menopause, Premature / Q000187:drug effects*; D018587:Oocyte Donation; D018579:Patient Selection; D011247:Pregnancy; D011256:Pregnancy Outcome; D014599:Uterus / Q000098:blood supply
D000970:Antineoplastic Agents