title: Alpha 2-adrenergic mechanisms of analgesia: strategies for improving their therapeutic window and identification of the novel, potent alpha 2A-adrenergic receptor agonist, S 18616.
authors.affiliation: Department of Psychopharmacology, Institut de Recherches Servier, Croissy-sur-Seine (Paris), France.
authors.forename: M J
authors.initials: MJ
authors.lastname: Millan
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000494:pharmacology*; D000698:Analgesia; D000818:Animals; D001933:Brain Stem / Q000502:physiology; D003000:Clonidine / Q000494:pharmacology; D006801:Humans; D051379:Mice; D010080:Oxazoles / Q000494:pharmacology*; D018341:Receptors, Adrenergic, alpha-2 / Q000187:drug effects / Q000502:physiology*; D011994:Recombinant Proteins / Q000187:drug effects; D013116:Spinal Cord / Q000502:physiology; D014162:Transfection
chemical_list: C547768:ADRA2A protein, human; C547769:Adra2a protein, mouse; D000316:Adrenergic alpha-Agonists; D010080:Oxazoles; D018341:Receptors, Adrenergic, alpha-2; D011994:Recombinant Proteins; C108919:S 18616; D003000:Clonidine