title: Molecular approaches to structure-function analysis of interleukin-8.
authors.affiliation: Department of Protein Engineering, Genentech, Inc., South San Francisco, California 94080, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Fairbrother
authors.forename: H B
authors.initials: HB
authors.lastname: Lowman
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D015703:Antigens, CD / Q000378:metabolism; D001667:Binding, Competitive; D002460:Cell Line; D002630:Chemotactic Factors / Q000737:chemistry / Q000378:metabolism; D004926:Escherichia coli / Q000235:genetics; D015870:Gene Expression; D006133:Growth Substances / Q000737:chemistry / Q000378:metabolism; D016209:Interleukin-8 / Q000737:chemistry* / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D008958:Models, Molecular; D008969:Molecular Sequence Data; D009154:Mutation / Q000235:genetics; D010455:Peptides / Q000737:chemistry / Q000378:metabolism; D010957:Plasmids; D018123:Receptors, Interleukin / Q000378:metabolism; D023062:Receptors, Interleukin-8A; D011994:Recombinant Proteins / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism; D016415:Sequence Alignment; D013329:Structure-Activity Relationship; D001620:beta-Thromboglobulin
chemical_list: D015703:Antigens, CD; D002630:Chemotactic Factors; D006133:Growth Substances; D016209:Interleukin-8; C061615:PPBP protein, human; D010455:Peptides; D018123:Receptors, Interleukin; D023062:Receptors, Interleukin-8A; D011994:Recombinant Proteins; D001620:beta-Thromboglobulin; C009862:connective tissue-activating peptide