title: Nutritional implications of xerostomia and rampant caries caused by serotonin reuptake inhibitors: a case study.
abstract: Serotonin reuptake inhibitors, such as fluoxetine, fenfluramine, and dexfenfluramine, are frequently used to treat obesity, depression, and bulimia. A common side effect of these medications is xerostomia, or dry mouth. A case study demonstrating the impact of drug-induced xerostomia on oral health and subsequent nutrition implications is presented. Rampant caries can result from a combination of xerostomia and inappropriate dietary and oral hygiene habits. Preventive dietary and dental guidelines are presented to assist nutrition and dental professionals in treating and counseling patients with xerostomia.
authors.affiliation: Tufts University School of Nutrition Science and Policy, Frances Stern Nutrition Center, New England Medical Center, Boston, MA 02111, USA.
authors.forename: L D
authors.initials: LD
authors.lastname: Boyd
authors.forename: J T
authors.initials: JT
authors.lastname: Dwyer
authors.forename: A
authors.initials: A
authors.lastname: Papas
mesh_terms: D000328:Adult; D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D003731:Dental Caries / Q000209:etiology*; D004032:Diet; D005260:Female; D005277:Fenfluramine / Q000009:adverse effects; D005473:Fluoxetine / Q000009:adverse effects; D006801:Humans; D009765:Obesity / Q000628:therapy*; D009909:Oral Health; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D014987:Xerostomia / Q000139:chemically induced* / Q000150:complications
chemical_list: D000928:Antidepressive Agents; D005277:Fenfluramine; D005473:Fluoxetine; D017367:Selective Serotonin Reuptake Inhibitors