[Disseminated mycobacteriosis with M. kansasii in a case of AIDS without HIV infection].
M. kansasii is an environmental Mycobacterium that causes disease mainly in patients with local or systemic immunodeficiency. We present a case with disseminated M. kansasii infection which led to a severe febrile illness lasting for 9 months. The patient had a combined acquired immunodeficiency syndrome (AIDS) which included CD4+ and CD8+ T-lymphocytopenia, monocytopenia and a deficiency in the IgG subclasses 2 and 4. HIV testing was repeatedly negative. In the published literature only 4 of 10 similar patients (this patient included) survived a disseminated M. kansasii infection. Eleven years after the disseminated infection with M. kansasii a second opportunistic infection, disseminated mollusca contagiosa and hyperparathyroidism, developed, and 14 years later the immunologic abnormalities persist.
Knoblauch
A
A
Pneumologische Abteilung, Kantonsspital St. Gallen.
Gloor
B W
BW
Flury
R
R
Galeazzi
R L
RL
Fierz
W
W
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy; D000995:Antitubercular Agents / Q000008:administration & dosage; D018791:CD4 Lymphocyte Count; D003131:Combined Modality Therapy; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007116:Immunization, Passive; D017710:Lymphocyte Transfusion; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000276:immunology / Q000628:therapy
D000995:Antitubercular Agents