Methodological issues in the use of biological markers in cancer epidemiology: cohort studies.
In this chapter we summarize the major strengths and weaknesses of cohort studies; consider how these characteristics influence the use of biomarkers in cohort studies; briefly review considerations of statistical power, design and the influence of measurement error in cohort studies; and discuss some of the emerging ethical considerations that relate to the use of biomarkers in prospective studies.
Hunter
D J
DJ
Harvard School of Public Health, Department of Epidemiology, Boston, MA 02115, USA.
D014408:Biomarkers, Tumor; D015331:Cohort Studies; D015340:Epidemiologic Research Design; D004992:Ethics, Medical; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000453:epidemiology*; D011446:Prospective Studies
D014408:Biomarkers, Tumor