title: [Anatomoclinical study of aortic insufficiency in atrophic polychondritis. Apropos of a case].
abstract: The authors report the anatomo-clinical features of aortic insufficiency complicating atrophic polychondritis, a rare inflammatory disease affecting mainly cartilaginous tissues. This case illustrates the inflammatory changes of the aortic wall, particularly progressive during this disease, responsible for aortic insufficiency and aneurysmal dilatation of the ascending aorta which required aortic valve replacement and prosthetic replacement of the ascending aorta. Histological analysis showed inflammatory lesions of the aortic wall comparable to the cartilaginous lesions described in this condition and suggesting a common physiopathogenic mechanism.
authors.affiliation: Service de cardiologie B, hôpital Bichat, Paris.
authors.forename: C
authors.initials: C
authors.lastname: Thuaire
authors.forename: H
authors.initials: H
authors.lastname: Benamer
authors.forename: E
authors.initials: E
authors.lastname: Brochet
authors.forename: P
authors.initials: P
authors.lastname: Aubry
authors.forename: G
authors.initials: G
authors.lastname: Hayem
authors.forename: C
authors.initials: C
authors.lastname: Vissuzaine
authors.forename: D
authors.initials: D
authors.lastname: Chatel
authors.forename: P
authors.initials: P
authors.lastname: Assayag
mesh_terms: D000328:Adult; D017545:Aortic Aneurysm, Thoracic / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D001022:Aortic Valve Insufficiency / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D001027:Aortography; D019917:Blood Vessel Prosthesis Implantation; D017548:Echocardiography, Transesophageal; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D011081:Polychondritis, Relapsing / Q000150:complications* / Q000175:diagnosis; D016896:Treatment Outcome