Failure to thrive, sacropenia and functional decline in the elderly.
At this time, there are no commonly accepted definitions for either the "failure to thrive" syndrome or for the newly described syndrome of sarcopenia. This lack of a common definition makes it difficult to contrast study results and understand the etiology of these syndromes. This article reviews the current state of understanding of these conditions and suggests potential mechanisms that may be further investigated.
Roubenoff
R
R
Physiology Laboratory and Sarcopenia Research Program, Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA.
Harris
T B
TB
D000368:Aged; D000375:Aging / Q000473:pathology / Q000502:physiology*; D001823:Body Composition; D005183:Failure to Thrive; D016330:Frail Elderly; D006801:Humans; D018482:Muscle, Skeletal / Q000473:pathology; D009133:Muscular Atrophy