Hepatoprotective effect of Liv-52 and kumaryasava on carbon tetrachloride induced hepatic damage in rats.
Oral administration of Liv-52 and kumaryasava to carbon tetrachloride (CCl4) treated rats improved growth. Kumaryasava was more effective in reducing the liver weight increase due to hepatotoxicity of CCl4. Hepatic arginase, cathepsin-B, acid phosphatase, ribonuclease activity which were decreased on CCl4 treatment was stimulated by both Liv-52 and kumaryasava. Results indicate that Liv-52 and kumaryasava have protective effect on hepatic enzyme induced due to CCl4 hepatotoxicity.
Kataria
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Division of Biochemistry and Food Science, Indian Veterinary Research Institute, Izatnagar, India.
Singh
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LN
D000818:Animals; D002252:Carbon Tetrachloride Poisoning / Q000188:drug therapy*; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy* / Q000209:etiology; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D008297:Male; D008515:Medicine, Ayurvedic; D010936:Plant Extracts / Q000627:therapeutic use*; D010946:Plants, Medicinal; D051381:Rats
D004338:Drug Combinations; D010936:Plant Extracts; C002614:Liv 52