Stress-wave-induced membrane permeation of red blood cells is facilitated by aquaporins.
Stress waves generated by lasers and extracorporeal lithotripters have been shown to transiently increase the permeability of the plasma membrane, without affecting cell viability. Molecules present in the medium can diffuse into the cytoplasm under the concentration gradient. Molecular uptake under stress waves correlates with the presence of functioning aquaporins in the plasma membrane.
Lee
S
S
Wellman Laboratories of Photomedicine, Massachusetts General Hospital, Department of Dermatology, Harvard Medical School, Boston 02114, USA.
McAuliffe
D J
DJ
Zhang
H
H
Xu
Z
Z
Taitelbaum
J
J
Flotte
T J
TJ
Doukas
A G
AG
D000818:Animals; D002463:Cell Membrane Permeability; D002470:Cell Survival; D002645:Chickens; D004910:Erythrocyte Membrane / Q000502:physiology*; D005434:Flow Cytometry; D005456:Fluorescent Dyes; D006801:Humans; D007473:Ion Channels / Q000502:physiology*; D007834:Lasers; D008096:Lithotripsy; D012235:Rhodamines; D013314:Stress, Mechanical; D014867:Water / Q000378:metabolism
D005456:Fluorescent Dyes; D007473:Ion Channels; D012235:Rhodamines; D014867:Water