title: Functionalized analogues of 5,8,10-trideazafolate as potential inhibitors of GAR Tfase or AICAR Tfase.
authors.affiliation: Department of Chemistry, Scripps Research Institute, La Jolla, CA 92037, USA.
authors.forename: D L
authors.initials: DL
authors.lastname: Boger
authors.forename: N E
authors.initials: NE
authors.lastname: Haynes
authors.forename: M S
authors.initials: MS
authors.lastname: Warren
authors.forename: L T
authors.initials: LT
authors.lastname: Gooljarsingh
authors.forename: J
authors.initials: J
authors.lastname: Ramcharan
authors.forename: P A
authors.initials: PA
authors.lastname: Kitos
authors.forename: S J
authors.initials: SJ
authors.lastname: Benkovic
mesh_terms: D002455:Cell Division / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005971:Glutamates / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D019877:Hydroxymethyl and Formyl Transferases / Q000037:antagonists & inhibitors*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D051027:Phosphoribosylaminoimidazolecarboxamide Formyltransferase; D051026:Phosphoribosylglycinamide Formyltransferase; D011799:Quinazolines / Q000737:chemistry / Q000494:pharmacology*; D016339:Spectrometry, Mass, Fast Atom Bombardment; D014407:Tumor Cells, Cultured
chemical_list: D004791:Enzyme Inhibitors; D005971:Glutamates; D011799:Quinazolines; D019877:Hydroxymethyl and Formyl Transferases; D051026:Phosphoribosylglycinamide Formyltransferase; D051027:Phosphoribosylaminoimidazolecarboxamide Formyltransferase