title: Evolution of the hydrogenosome.
abstract: Since its discovery almost 25 years ago the enigmatic hydrogenosome, a redox organelle of anaerobic unicellular eukaryotes, has puzzled evolutionists as to its origin and function. Synthesis of recent molecular, physiological and morphological studies now favours the hypothesis that hydrogenosomes derived from a modification of pre-existing mitochondria, and argues against the previously held view that the hydrogenosome had a polyphyletic origin. These data provide evidence for a more ancient origin of mitochondria than hitherto thought.
authors.affiliation: Microbiology Group, School of Pure and Applied Biology, University of Wales Cardiff, UK. Biagini@cardiff.ac.uk
authors.forename: G A
authors.initials: GA
authors.lastname: Biagini
authors.forename: B J
authors.initials: BJ
authors.lastname: Finlay
authors.forename: D
authors.initials: D
authors.lastname: Lloyd
mesh_terms: D000818:Animals; D006859:Hydrogen / Q000378:metabolism; D008928:Mitochondria / Q000378:metabolism; D010802:Phylogeny; D014246:Trichomonas vaginalis / Q000145:classification* / Q000378:metabolism
chemical_list: D006859:Hydrogen