title: Invasive pulmonary aspergillosis with cerebromeningeal involvement after short-term intravenous corticosteroid therapy in a patient with asthma.
abstract: The present case report describes a case of invasive pulmonary aspergillosis with cerebromeningeal invasion in an asthmatic non-immunocompromised patient. This fatal complication occurred despite early anti-fungal antibiotherapy after a 2-week course of intravenous corticosteroid therapy for treatment of an exacerbated asthma. Diagnostic and therapeutic procedures are discussed.
authors.affiliation: Service de Réanimation Médicale, Hôpitaux Universitaires de Strasbourg, France.
authors.forename: E
authors.initials: E
authors.lastname: Monlun
authors.forename: F
authors.initials: F
authors.lastname: de Blay
authors.forename: C
authors.initials: C
authors.lastname: Berton
authors.forename: B
authors.initials: B
authors.lastname: Gasser
authors.forename: A
authors.initials: A
authors.lastname: Jaeger
authors.forename: G
authors.initials: G
authors.lastname: Pauli
mesh_terms: D000368:Aged; D001228:Aspergillosis / Q000175:diagnosis / Q000209:etiology*; D001249:Asthma / Q000188:drug therapy*; D001927:Brain Diseases / Q000382:microbiology; D017809:Fatal Outcome; D005260:Female; D005938:Glucocorticoids / Q000009:adverse effects*; D006801:Humans; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000209:etiology*; D008775:Methylprednisolone / Q000009:adverse effects*
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone