[The value of diagnostic methods used to assess the response to treatment in patients with limited small cell lung carcinoma].
Tumor response is used as a main criterion whether or not the treatment yields an anticancer activity. The tumor response criteria are defined by WHO recommendation but little is known about the tests must be used. The aim of this paper was to compare the degree of response to the treatment of 268 patients with limited small cell lung cancer, using independently 3 methods: radiological, bronchoscopic and cytological of bronchial material. Particular categories of response (CR, PR NR and presence or absence of carcinomatous cells) were related to survival time of patients independently to method of assessment. Multivarinte Cox analysis selected 3 parameters related to 3 different methods as independent survival risk factors. We conclude that each of diagnostic method (chest x-ray, bronchoscopy, cytological examination of bronchial material yield independent information correlated with survival risk of particular patient.
Wiatr
E
E
III Kliniki Gruzlicy i Chorób Płuc, Warszawie.
Bestry
I
I
Załeska
J
J
Zych
J
J
Lewandowski
Z
Z
Rowińska-Zakrzewska
E
E
D001980:Bronchi / Q000473:pathology; D001999:Bronchoscopy; D018288:Carcinoma, Small Cell / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000628:therapy; D015999:Multivariate Analysis; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome