title: Hydranencephaly with renal dysgenesis: a coincidental finding? Case report with review of the literature.
abstract: We present the case of a female fetus aborted in the 20th week of gestation due to severely dysplastic kidneys, anhydramnios and hydranencephalus. The combination of these malformations is extremely rare, resulting in only 4 cases described so far. Our case is the first ever presented in a female showing polycystic-dysplastic kidneys. Multiple multinucleated neurons were a remarkable finding in the remnants of the brain. The possibility of an underlying genetic disorder is discussed, together with a brief review of the literature to date.
authors.affiliation: Department of Pathology, University of Innsbruck, Austria.
authors.forename: A
authors.initials: A
authors.lastname: Gschwendtner
authors.forename: T
authors.initials: T
authors.lastname: Mairinger
authors.forename: E
authors.initials: E
authors.lastname: Soelder
authors.forename: A
authors.initials: A
authors.lastname: Alge
authors.forename: A
authors.initials: A
authors.lastname: Kreczy
mesh_terms: D000028:Abortion, Induced; D000328:Adult; D005260:Female; D005865:Gestational Age; D006801:Humans; D006832:Hydranencephaly / Q000150:complications* / Q000175:diagnosis; D007668:Kidney / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D007690:Polycystic Kidney Diseases / Q000150:complications* / Q000151:congenital / Q000175:diagnosis; D011247:Pregnancy; D016216:Ultrasonography, Prenatal