Mycoplasma genes: a case for reflective annotation.
Although function can be assigned to genome sequence by homology at a macroscopic level, this can be misleading in the absence of data on enzyme activities. Together, such data can reveal whether open reading frames are expressed, identify multienzyme function and point to 'orphan' function. Because of their small size and small genomes, the genome sequences of some Mycoplasma spp. are very amenable to detailed analyses.
Pollack
J D
JD
Dept of Medical Microbiology and Immunology, College of Medicine, Ohio State University, Columbus 43210, USA. pollack.1@osu.edu
D005798:Genes, Bacterial; D009174:Mycoplasma / Q000235:genetics*; D013329:Structure-Activity Relationship