title: Esophageal replacement for end-stage benign esophageal disease.
abstract: The fact that esophageal resection and foregut reconstruction for benign disease can be performed with only a 2% mortality and minimal morbidity is encouraging news to patients who are crippled by the various manifestations of end-stage disease. The continuation of slow, anxious, and socially restricted alimentation or the maintenance of nutrition by enteral or parenteral means is unnecessary. The patient should be referred to a unit skilled in evaluating foregut function, performing esophageal replacement surgery, and caring for patients in the perioperative period. In our experience, the colon, when available, is the preferred conduit for esophageal replacement over the long term. Even though some subtle preoperative symptoms of foregut dysfunction may persist after surgery, the overall outcome is generally judged to be satisfactory. Indeed, patients can re-enter society and live a normal and fulfilled life after remedial surgery. Prolonged attempts at medical management of patients with severe derangements of esophageal structure and function are not warranted. Long-term esophageal replacement for severe end-stage benign disease can be accomplished with low mortality, a high degree of success, and a marked improvement in the quality of alimentation. Reconstruction restores the pleasure of eating and is viewed by the patient to be highly successful.
authors.affiliation: Department of Surgery, University of Southern California School of Medicine, Los Angeles, USA.
authors.forename: T J
authors.initials: TJ
authors.lastname: Watson
authors.forename: J H
authors.initials: JH
authors.lastname: Peters
authors.forename: T R
authors.initials: TR
authors.lastname: DeMeester
mesh_terms: D003106:Colon / Q000601:surgery; D004935:Esophageal Diseases / Q000601:surgery*; D016629:Esophagectomy / Q000379:methods; D006801:Humans; D007583:Jejunum / Q000637:transplantation; D013270:Stomach / Q000601:surgery; D016896:Treatment Outcome; D014628:Vagotomy