A biomechanical double sac (pericardium-Pebax) for specially shaped artificial ventricles: a computerized study to evaluate its mechanical and volumetric properties.
For original ovoid shaped artificial ventricles, a biomechanical double sac consisting of a biological sac (porcine pericardium) as the blood contact interface and a synthetic sac (Pebax 3533) as the mechanical support to assume systolic-diastolic dynamic constraints was conceived. The volumetric and mechanical properties were assessed with a three-dimensional modeling of Pebax sacs and computerized simulations of their systolic distortions for both right and left ventricular configurations. The stresses and strains of these sacs were represented as quantitative mappings for a maximum end-systolic state and were below the respective threshold values above which the Pebax material is jeopardized for permanent structure impairment. After fatigue tests applied on Pebax strips under the alleged working conditions of Pebax sacs, the material structure was unchanged and maintained its intrinsic mechanical properties. The theoretical maximum stroke volumes were 74.4 cm3 and 62.4 cm3 for the left and right ventricular configurations, respectively. With these mechanical and volumetric features, the biomechanical double sac concept was considered valid and could be provided for a consequent specific total artificial heart.
Chatel
D
D
Département de Chirurgie Cardiaque, Hopital Bichat, Paris, France.
Delamare
L
L
Dang
P
P
Lebouvier
D
D
Trocherie
F
F
D000818:Animals; D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D003198:Computer Simulation; D005240:Feasibility Studies; D005976:Glutaral / Q000737:chemistry; D006352:Heart Ventricles; D006354:Heart, Artificial / Q000592:standards*; D008962:Models, Theoretical; D010496:Pericardium; D011108:Polymers; D013318:Stroke Volume; D013552:Swine; D013718:Tensile Strength
D001672:Biocompatible Materials; D011108:Polymers; D005976:Glutaral