[Significance of monitoring cytokine levels in the prognosis of acute pancreatitis].
The importance of cytokines as mediators and immunomodulators is increasing in all disciplines. Acute pancreatitis is a disease where the trigger mechanisms of the inflammation and thus also the influence of cytokines are very closely associated and are therefore apparent. The authors investigated on that model the levels of IL-2, IL-6, IL-8, IL-2r and neopterin in relation to the stage of the disease and time. They provided evidence in a group of 33 patients that the cytokine level indicates very accurately the stage of the disease and thus also its prognosis. For the assessment proper of the diagnosis the cytokine level is less important as the rise of the level is quite unspecific.
Král
V
V
I. chirurgická klinika FN, Olomouc.
Havlík
R
R
Grosmanová
T
T
Bartek
J
J
D000208:Acute Disease; D015415:Biomarkers / Q000097:blood; D001708:Biopterins / Q000031:analogs & derivatives / Q000097:blood; D006801:Humans; D007378:Interleukins / Q000097:blood*; D019798:Neopterin; D010195:Pancreatitis / Q000097:blood / Q000175:diagnosis*; D011379:Prognosis
D015415:Biomarkers; D007378:Interleukins; D001708:Biopterins; D019798:Neopterin