3 beta,5 alpha-Dihydroxycholestan-6-one exists in human blood.
3 beta,5 alpha-Dihydroxycholestan-6-one was detected in fresh human plasma at the concentration of 14-44 ng/mL. The oxysterol binds specifically to phorbol ester specific binding protein in vitro, and may be an endogenous ligand of the protein.
Yamaguchi
M
M
Graduate School of Pharmaceutical Sciences, University of Tokyo, Japan.
Endo
Y
Y
Shimizu
M
M
Yamamoto
K
K
Yamada
S
S
Shudo
K
K
D000818:Animals; D002417:Cattle; D002470:Cell Survival / Q000502:physiology; D002778:Cholestanones / Q000097:blood*; D006801:Humans; D011485:Protein Binding; D013755:Tetradecanoylphorbol Acetate / Q000097:blood*
D002778:Cholestanones; C082633:yakkasterone; D013755:Tetradecanoylphorbol Acetate