Vitamin E treatment in tardive dystonia.
Tardive dystonia is a disorder characterized by abnormally sustained posturing associated with the use of dopamine-receptor blocking agents such as antipsychotic drugs. However, the structural pathologic and pathophysiologic features of this disorder are unknown, and no consistently effective pharmacologic treatment is available. Patients with tardive dystonia mostly are young men. We present the case of one substantially improved with treatment by 1200 mg/d (IU) of vitamin E.
Dannon
P N
PN
Division of Psychiatry, Chaim Sheba Medical Center, Tel HaShomer, Israel.
Grunhaus
L
L
Iancu
I
I
Braf
A
A
Lepkifker
E
E
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use; D004421:Dystonia / Q000139:chemically induced / Q000188:drug therapy*; D006801:Humans; D008297:Male; D014810:Vitamin E / Q000627:therapeutic use*
D014150:Antipsychotic Agents; D014810:Vitamin E