Applications of nuclear magnetic resonance spectroscopy and molecular modeling to the study of protein-carbohydrate interactions.
This work provides an overview of the applications of NMR to the study of protein-carbohydrate interactions. The use of TR-NOE experiments in this context is given. In particular, the study of Ricin/lactose and Hevein/chitobiose complexes is detailed.
Poveda
A
A
Servicio Interdepartamental de Investigación, Facultad de Ciencias, Universidad Autónoma de Madrid, Spain.
Asensio
J L
JL
Espinosa
J F
JF
Martin-Pastor
M
M
Cañada
J
J
Jiménez-Barbero
J
J
D000818:Animals; D023181:Antimicrobial Cationic Peptides; D001665:Binding Sites; D002240:Carbohydrate Sequence; D002241:Carbohydrates / Q000737:chemistry*; D003196:Computer Graphics; D004187:Disaccharides / Q000737:chemistry; D006801:Humans; D007785:Lactose / Q000737:chemistry; D037102:Lectins / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D008969:Molecular Sequence Data; D037121:Plant Lectins; D010940:Plant Proteins / Q000737:chemistry; D011506:Proteins / Q000737:chemistry*; D012276:Ricin / Q000737:chemistry
D023181:Antimicrobial Cationic Peptides; D002241:Carbohydrates; D004187:Disaccharides; D037102:Lectins; D037121:Plant Lectins; D010940:Plant Proteins; D011506:Proteins; C045875:hevein; C032438:chitobiose; D012276:Ricin; D007785:Lactose