title: Osteoarticular and muscle infectious lesions in patients with the human immunodeficiency virus.
abstract: Between 1988 and 1995, 1832 HIV positive patients were evaluated in our institution. We studied the epidemiologic, immunologic and bacteriologic data, laboratory tests, and X-Ray films in those with musculoskeletal infection. We reviewed twenty-one cases of musculoskeletal infection in twenty patients aged 23-35 years (mean 28,6 years, M:F= 15:5). In all of them risk factor for HIV was intravenous drug abuse. The number of CD4 positive lymphocytes ranged from 0,003 to 0,5 10(9)/l. Staphylococcus aureus was the organism responsible of the infection in twelve cases, all active intravenous drug abusers at the time the diagnosis was done. The remaining causative agents were: Mycobacterium tuberculosis (3 cases), Candida albicans (2 cases), Salmonella subgroup 1 (1 case), Neisseria gonorrhoeae (1 case), Pseudomona aeruginosa (1 case) and Streptococcus agalactiae (1 case). Fifteen infections were diagnosed between 1988 and 1991 and 6 between 1992 and 1995. Musculoskeletal infectious lesions in HIV positive patients in our country are related in the majority of cases to intravenous drug abuse. In the last four years due to a National medical health care plan conducted to educate this group of people the number of musculoskeletal infections is decreasing.
authors.affiliation: Rheumatology Unit, Hosp. NS Aránzazu, San Sebastián, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Belzunegui
authors.forename: C
authors.initials: C
authors.lastname: Gonzalez
authors.forename: L
authors.initials: L
authors.lastname: Lopez
authors.forename: I
authors.initials: I
authors.lastname: Plazaola
authors.forename: O
authors.initials: O
authors.lastname: Maiz
authors.forename: M
authors.initials: M
authors.lastname: Figueroa
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D000038:Abscess / Q000453:epidemiology / Q000382:microbiology*; D000328:Adult; D001170:Arthritis, Infectious / Q000453:epidemiology / Q000382:microbiology*; D001424:Bacterial Infections / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D002176:Candida albicans / Q000302:isolation & purification; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D009135:Muscular Diseases / Q000453:epidemiology / Q000382:microbiology*; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification; D010019:Osteomyelitis / Q000453:epidemiology / Q000382:microbiology*; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D013211:Staphylococcus aureus / Q000302:isolation & purification; D019966:Substance-Related Disorders / Q000150:complications*