title: Cone electroretinogram to chromatic stimuli in myopic eyes.
abstract: The cone electroretinograms (ERGs) to different chromatic stimuli were recorded in myopic subjects. Ganzfeld color flashes under bright white background illumination were used to elicit short-wavelength-sensitive (S-), and mixed long-(L-) and middle-(M-) wavelength-sensitive cone ERGs. Nineteen subjects with mild myopia (between -3.0 and -6.0 D), 12 subjects with high myopia (greater than -6.25 D) but without chorioretinal atrophy or posterior staphyloma, and 22 age-matched normal controls were compared. The S-cone and L,M-cone b-wave amplitudes decreased progressively with increasing myopia. The amplitudes of the S-cone and the L,M-cone b-wave were significantly lower in highly myopic subjects, as compared with controls. The implicit times of both b-waves were normal in most myopic subjects. The S-cone and the L,M-cone ERGs were almost equally affected in myopic eyes. The selective reduction of the S-cone pathway in high myopia, reported previously, may not originate from the other retina.
authors.affiliation: Department of Ophthalmology, Toyama Medical and Pharmaceutical University, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
authors.forename: K
authors.initials: K
authors.lastname: Nitta
authors.forename: M
authors.initials: M
authors.lastname: Kamiyama
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003118:Color Perception / Q000502:physiology*; D004596:Electroretinography; D006801:Humans; D009216:Myopia / Q000503:physiopathology*; D017949:Retinal Cone Photoreceptor Cells / Q000503:physiopathology*; D013053:Spectrophotometry