title: Sick building syndrome--a wolf in sheep's clothing.
abstract: OBJECTIVE
  Reading this article will acquaint the reader with possible outcomes associated with the diagnosis of "sick building syndrome." The definition, epidemiology, and precipitating events of this symptom complex are distinguished from other defined building-related illnesses.
  
  
  METHODS
  The author's experience with many patients presenting with this diagnostic label and selected studies on indoor pollution and "sick building syndrome" are carefully reviewed.
  
  
  METHODS
  Pertinent scientific investigations on "sick building syndrome" and previously published reviews on this and related subjects that met the educational objectives were critically reviewed.
  
  
  RESULTS
  "Sick building syndrome" is a pseudodiagnosis composed of nonspecific, transient symptoms without proven biologic markers. Its application in the clinical setting invites frequent subsequent linkage to other similar vague diagnoses associated with chronic debility and lack of therapeutic intervention.
  
  
  CONCLUSIONS
  The reader is encouraged to avoid the use of this term in favor of a simpler, descriptive diagnosis (e.g., transient office-related annoyance and/or irritation) or if this seems inadequate, adoption of the diagnostic label of "idiopathic building intolerance."
authors.affiliation: Oregon Health Sciences University, Division of Allergy and Clinical Immunology, Portland, USA.
authors.forename: E J
authors.initials: EJ
authors.lastname: Bardana
mesh_terms: D006801:Humans; D012141:Respiratory Tract Infections / Q000635:transmission; D018877:Sick Building Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000382:microbiology