Phytochemical analysis of Geigeria alata and Francoeuria crispa essential oils.
Phytochemical analyses of Geigeria alata (Benth. & Hook.) and Francoeuria crispa (Forssk., Cas.) (Asteraceae) essential oils were performed. G. alata oil showed moderate in vitro cytotoxicity (IC50, micrograms/ml against tumor cells; P388: 2.0, A-549: 2.5 and HT-29: 5.0), and also showed weak anti-HIV activity. S-Carvotanacetone, the major component of F. crispa oil (93.0%), was isolated and its structure was elucidated by 2D-NMR analysis.
Ross
S A
SA
el Sayed
K A
KA
el Sohly
M A
MA
Hamann
M T
MT
Abdel-Halim
O B
OB
Ahmed
A F
AF
Ahmed
M M
MM
D000818:Animals; D019380:Anti-HIV Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity; D002470:Cell Survival / Q000187:drug effects; D008401:Gas Chromatography-Mass Spectrometry; D006678:HIV / Q000187:drug effects / Q000502:physiology*; D006801:Humans; D007941:Leukemia P388; D051379:Mice; D009822:Oils, Volatile / Q000032:analysis*; D010946:Plants, Medicinal; D010947:Plants, Toxic; D014407:Tumor Cells, Cultured; D014779:Virus Replication / Q000187:drug effects
D019380:Anti-HIV Agents; D000972:Antineoplastic Agents, Phytogenic; D009822:Oils, Volatile