title: Virulence patterns of Escherichia coli K1 strains associated with neonatal meningitis.
abstract: The prevalence of the ibe10 gene, of the pap, afa, and sfa adhesin-encoding operons, and of a 14.9-kb rrn-containing HindIII fragment was studied for 67 Escherichia coli neonatal meningitis strains, 58 E. coli K1 commensal strains, and 47 E. coli blood isolates from neonates without meningitis. ibe10, sfa, and the 14.9-kb HindIII fragment were observed significantly more often in the meningitis strains than in blood or commensal strains.
authors.affiliation: Laboratoire de Recherche en Bactériologie Pédiatrique (ER 321), Hôpital Robert Debré and Université Denis Diderot-Paris 7, France. edouard.Bingen@rdb.ap_hop_paris.fr
authors.forename: E
authors.initials: E
authors.lastname: Bingen
authors.forename: S
authors.initials: S
authors.lastname: Bonacorsi
authors.forename: N
authors.initials: N
authors.lastname: Brahimi
authors.forename: E
authors.initials: E
authors.lastname: Denamur
authors.forename: J
authors.initials: J
authors.lastname: Elion
mesh_terms: D018829:Adhesins, Bacterial / Q000235:genetics; D001426:Bacterial Proteins / Q000235:genetics; D015247:Deoxyribonuclease HindIII; D004926:Escherichia coli / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000097:blood / Q000134:cerebrospinal fluid / Q000382:microbiology*; D029968:Escherichia coli Proteins; D005243:Feces / Q000382:microbiology; D005798:Genes, Bacterial; D006801:Humans; D007231:Infant, Newborn; D008565:Membrane Proteins / Q000235:genetics; D016920:Meningitis, Bacterial / Q000097:blood / Q000134:cerebrospinal fluid / Q000382:microbiology*; D009876:Operon; D016133:Polymerase Chain Reaction; D015183:Restriction Mapping; D014774:Virulence
chemical_list: D018829:Adhesins, Bacterial; D001426:Bacterial Proteins; C096350:CusC protein, E coli; D029968:Escherichia coli Proteins; D008565:Membrane Proteins; D015247:Deoxyribonuclease HindIII