title: Fibroelastolytic papulosis of the neck: a report of 20 cases.
abstract: The clinical and histological features of the entities known as 'white fibrous papulosis of the neck' (WFPN) and 'acquired elastolysis of the papillary dermis simulating pseudoxanthoma elasticum' (PDE) are not clearly defined. This study was conducted to compare our experience of WFPN/PDE with those described in the literature. Twenty patients presented at our institution with papular eruptions involving the neck. The asymptomatic lesions, which ranged in colour from normal skin tones to yellowish, were isolated or coalescent. Microscopically, the papules showed elastolysis and fibrosis of the upper reticular and papillary dermis. A review of the literature shows similar characteristics in cases reported as WFPN and PDE. This study indicates that WFPN and PDE are variants of a single disorder that can be more precisely defined as 'fibroelastolytic papulosis of the neck' and which appears to be a manifestation of intrinsic skin ageing.
authors.affiliation: Laboratory of Dermatopathology, San Gallicano Institute of Dermatology, Rome, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Balus
authors.forename: A
authors.initials: A
authors.lastname: Amantea
authors.forename: P
authors.initials: P
authors.lastname: Donati
authors.forename: M
authors.initials: M
authors.lastname: Fazio
authors.forename: M C
authors.initials: MC
authors.lastname: Giuliano
authors.forename: M
authors.initials: M
authors.lastname: Bellocci
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003240:Connective Tissue Diseases / Q000473:pathology; D004547:Elastic Tissue / Q000473:pathology*; D005260:Female; D005355:Fibrosis; D006801:Humans; D008875:Middle Aged; D009333:Neck; D012867:Skin / Q000473:pathology*