Superficial Salmonella abscesses in two siblings with sickle cell diseases.
Salmonella infection in sickle cell disease patients is generally well-known but presentation as superficial abscess is relatively uncommon. Two sisters aged 4 1/2 and 6 years presented with superficial subcutaneous abscesses that were caused by the same strain of Salmonella enteriditis group C. Despite in vitro susceptibility with a MIC of 0.03 microgram/ml and an adequate dosage of ciprofloxacin there was a relapse with widespread dissemination of the same organism in the younger sister who subsequently developed multiple osteolytic infections. Change of treatment to chloramphenicol produced a cure in both patients.
Mansoury
B
B
Department of Paediatrics, King Fahd Armed Forces Hospital, Jeddah, Saudi Arabia.
Barbor
P H
PH
Feteih
J
J
Rotimi
V O
VO
D000038:Abscess / Q000188:drug therapy / Q000209:etiology*; D000755:Anemia, Sickle Cell / Q000150:complications*; D016470:Bacteremia / Q000188:drug therapy / Q000209:etiology*; D002648:Child; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D008826:Microbial Sensitivity Tests; D010019:Osteomyelitis / Q000209:etiology*; D012008:Recurrence; D012480:Salmonella Infections / Q000188:drug therapy / Q000209:etiology*; D012477:Salmonella enteritidis