title: Histopathological changes of primary HIV infection. Description of three cases and review of the literature.
abstract: The histopathological changes observed in the cutaneous rash of three patients who suffered the acute phase of HIV infection are described. In all three patients a perivascular and interstitial inflammatory infiltrate was present in the upper and mid-reticular dermis. In one biopsy isolated areas of epidermal necrosis were observed and in the two other biopsies a perifollicular inflammatory infiltrate was detected with perforation in one case. Furthermore, a periductal infiltrate was observed in one of these biopsies.
authors.affiliation: Department of Dermatology, Hospital de la Sta, Barcelona, Spain.
authors.forename: M A
authors.initials: MA
authors.lastname: Barnadas
authors.forename: M
authors.initials: M
authors.lastname: Alegre
authors.forename: E
authors.initials: E
authors.lastname: Baselga
authors.forename: L
authors.initials: L
authors.lastname: Randazzo
authors.forename: N
authors.initials: N
authors.lastname: Margall
authors.forename: N
authors.initials: N
authors.lastname: Rabella
authors.forename: R
authors.initials: R
authors.lastname: Curell
authors.forename: J M
authors.initials: JM
authors.lastname: de Moragas
mesh_terms: D000328:Adult; D005076:Exanthema / Q000150:complications / Q000473:pathology*; D015658:HIV Infections / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019226:Oral Ulcer / Q000150:complications / Q000473:pathology*