title: Alcohol abuse: a risk factor for surgical wound infections?
abstract: BACKGROUND
  The incidence of postoperative surgical site infections (SSIs) is difficult to estimate because of the current trend of early discharge after surgery. Both operation-related and host factors should be taken into consideration in the prevention of SSIs. We wanted to determine the actual incidence of SSIs and evaluate the risk factors in our clinic, using an extended follow-up period of 30 days after operations.
  
  
  METHODS
  We performed a prospective follow-up survey of SSIs over a 3.5-month period including a 1-month follow-up after discharge with written instructions and a telephone survey. The SSIs were defined according to Centers for Disease Control and Prevention criteria. Forty-three patient parameters were recorded, and risk factors for SSI were sought and tested by using multiple logistic regression analysis.
  
  
  RESULTS
  The follow-up was completed in 772 of 807 patients. The SSI rates in these patients were 5.3% in clean, 7.1% in clean-contaminated, 6.2% in contaminated, and 28.1% in dirty operations. Seventy-one percent of infections were not diagnosed until after discharge from the hospital. According to multiple logistic regression analysis, alcohol abuse (p < 0.0001), wound contamination class (p < 0.05), and operation duration of over 2 hours (p < 0.05) were independently significant risk factors for SSI.
  
  
  CONCLUSIONS
  A major portion of SSIs are found only after follow-up is extended during the postdischarge period. Alcohol abuse is a significant risk factor for SSI and should be taken into account when determining the susceptibility of an individual patient.
authors.affiliation: Department of Surgery, University of Turku, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Rantala
authors.forename: O P
authors.initials: OP
authors.lastname: Lehtonen
authors.forename: J
authors.initials: J
authors.lastname: Niinikoski
mesh_terms: D000328:Adult; D000368:Aged; D000437:Alcoholism / Q000150:complications / Q000453:epidemiology*; D016009:Chi-Square Distribution; D005260:Female; D005387:Finland / Q000453:epidemiology; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D013503:Surgery Department, Hospital / Q000706:statistics & numerical data; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000209:etiology; D015996:Survival Rate