The effect of a peripheral mononeuropathy on immunoreactive (ir)-galanin release in the spinal cord of the rat.
The pattern of ir-galanin release in the spinal cord of rats with a peripheral mononeuropathy was studied. On the side of the cord ipsilateral to the nerve injury enhanced ir-galanin release was found in the superficial dorsal horn. It is probable that, after nerve injury, some primary afferent neurons spontaneously release galanin from their central terminals.
Colvin
L A
LA
Department of Preclinical Veterinary Sciences, Royal (Dick) School of Veterinary Studies, University of Edinburgh, Summerhall, UK. lcolvin@lab0.vet.ed.ac.uk
Mark
M A
MA
Duggan
A W
AW
D000818:Animals; D019004:Galanin / Q000032:analysis / Q000378:metabolism*; D007091:Image Processing, Computer-Assisted; D008026:Ligation; D008297:Male; D008839:Microelectrodes; D009408:Nerve Compression Syndromes / Q000378:metabolism*; D009475:Neurons, Afferent / Q000502:physiology; D010146:Pain / Q000503:physiopathology; D051381:Rats; D017208:Rats, Wistar; D012018:Reflex; D012584:Sciatic Nerve / Q000293:injuries* / Q000601:surgery; D013116:Spinal Cord / Q000737:chemistry / Q000166:cytology / Q000378:metabolism*
D019004:Galanin