title: Hepatic infarction with portal thrombosis.
abstract: A case of hepatic infarction with portal thrombosis is reported. A 63-year-old woman with liver cirrhosis and esophageal varices was admitted for treatment of the esophageal varices. Endoscopic variceal ligation (EVL) and endoscopic injection sclerotherapy (EIS) were performed. Two months later, she experienced right hypochondralgia and right flank pain. Serum transaminase levels were suddenly elevated, and computed tomography scans of the liver showed multiple small nodular lesions. Her condition worsened, and she died of hepatic failure. Autopsy revealed splenic and portal vein thrombosis, multiple hepatic infarction, and evidence of chronic pancreatitis. We believe that liver cirrhosis and chronic pancreatitis were the main risk factors for the portal thrombosis, and the treatment for esophageal varices appeared to have triggered the thrombosis. The hepatic infarction was caused by the portal thrombosis.
authors.affiliation: Department of Internal Medicine (Section 1), Sapporo Medical University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Yamashita
authors.forename: H
authors.initials: H
authors.lastname: Tsukuda
authors.forename: Y
authors.initials: Y
authors.lastname: Mizukami
authors.forename: J
authors.initials: J
authors.lastname: Ito
authors.forename: S
authors.initials: S
authors.lastname: Ikuta
authors.forename: Y
authors.initials: Y
authors.lastname: Kondo
authors.forename: H
authors.initials: H
authors.lastname: Kinoshita
authors.forename: Y
authors.initials: Y
authors.lastname: Fujisawa
authors.forename: K
authors.initials: K
authors.lastname: Imai
mesh_terms: D016145:Endoscopy, Digestive System; D004932:Esophageal and Gastric Varices / Q000150:complications / Q000628:therapy; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007238:Infarction / Q000175:diagnosis / Q000209:etiology*; D008026:Ligation; D008099:Liver / Q000098:blood supply*; D008103:Liver Cirrhosis / Q000150:complications; D008875:Middle Aged; D011169:Portal Vein; D015911:Sclerotherapy; D013924:Thrombophlebitis / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed