Occupational allergic contact dermatitis from carnosol, a naturally-occurring compound present in rosemary.
A 56-year-old man, working in a food processing factory, developed contact dermatitis of his hands, forearms, and face after the introduction of a new herb extract (Rosmanox) made from the leaves of rosemary (Rosmarinus officinalis). He reacted to carnosol, the main constituent of Rosmanox. 226 controls were negative. To our knowledge, this is the 1st reported case of contact dermatitis from carnosol.
Hjorther
A B
AB
Department of Dermatology, Københavns Amtssygehus Gentofte, Hellerup, Denmark.
Christophersen
C
C
Hausen
B M
BM
Menné
T
T
D045784:Abietanes; D000975:Antioxidants / Q000009:adverse effects; D003877:Dermatitis, Contact / Q000209:etiology*; D009783:Dermatitis, Occupational / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010616:Phenanthrenes / Q000009:adverse effects*; D010936:Plant Extracts / Q000009:adverse effects* / Q000737:chemistry*; D017365:Spices
D045784:Abietanes; D000975:Antioxidants; D010616:Phenanthrenes; D010936:Plant Extracts; C068623:carnosol