title: [Teleangiectasia haemorrhagica hereditaria. Surgical therapy of malignant skin tumors (Osler-Weber-Rendu disease].
abstract: A 65 year old male patient was diagnosed with hereditary hemorrhagic telangiectasia at 30. During recent years he has suffered frequent, almost daily, nose bleeds causing anemia and making several blood transfusions necessary. In the past 2-3 years, the patient has developed multiple squamous cell carcinomas on the face. These unusually large tumours were treated by micrographic surgery using paraffin sections and the defects dosed with a variety of flaps and grafts. Several solar keratoses were also removed. If hemostasis parameters are normal, skin surgery can be performed without hesitation in hereditary hemorrhagic telangiectasia.
authors.affiliation: Universitäts-Hautklinik, Tübingen.
authors.forename: H
authors.initials: H
authors.lastname: Breuninger
authors.forename: O
authors.initials: O
authors.lastname: Bogenschütz
authors.forename: E
authors.initials: E
authors.lastname: Konrad
authors.forename: G
authors.initials: G
authors.lastname: Rassner
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005153:Facial Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D015580:Mohs Surgery; D009378:Neoplasms, Multiple Primary / Q000473:pathology / Q000601:surgery*; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000473:pathology / Q000601:surgery*