[Androgen-producing adrenocortical adenoma in childhood. Pitfalls of differential diagnosis].
A two-year-old girl presented with clitoromegaly and an abdominal mass. Diagnostic procedures including sonography, computerized tomography, scintigraphy and measurement of catecholamines in urine excluded neuroblastoma, but suspected Wilms-tumor. Before completing the steroid measurements therapy was initiated according to Wilms-tumor (preoperative cytostatic therapy followed by surgical removal of the tumor). Morphology of the tumor, the serum and urinary steroid profile proved a benign adrenocortical adenoma producing mainly delta 5-steroids including the weak androgen, dehydroepiandrosterone.
Gyulay
K
K
II. sz. Gyermekgyógyászati Klinika, Semmelweis Orvostudományi Egyetem, Budapest.
Niederland
T
T
Rudas
G
G
Kontor
E
E
Zalatnai
A
A
Kopper
L
L
Homoki
J
J
Borsi
J
J
Sólyom
J
J
D000236:Adenoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D000306:Adrenal Cortex Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D002675:Child, Preschool; D005260:Female; D006801:Humans; D011379:Prognosis; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography