title: Disseminated infection due to Bipolaris australiensis in a young immunocompetent man: case report and review.
abstract: We report a case of disseminated infection due to Bipolaris australiensis in a 21-year-old immunocompetent Pakistani man. He presented with fever and jaundice. Examination revealed a mass in the right lung, mediastinal lymphadenopathy, a pericardial effusion, and abdominal masses obstructing and invading the common bile duct and right ureter. Histological examination and culture of a biopsy specimen of the hilar mass yielded the fungal pathogen B. australiensis. The patient was treated successfully with amphotericin B and itraconazole.
authors.affiliation: Hospital for Tropical Diseases, London, United Kingdom.
authors.forename: K L
authors.initials: KL
authors.lastname: Flanagan
authors.forename: A D
authors.initials: AD
authors.lastname: Bryceson
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002779:Cholestasis / Q000382:microbiology; D004359:Drug Therapy, Combination; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008172:Lung Diseases, Fungal / Q000382:microbiology; D008206:Lymphatic Diseases / Q000382:microbiology; D008297:Male; D008477:Mediastinal Diseases / Q000382:microbiology; D003904:Mitosporic Fungi / Q000254:growth & development / Q000302:isolation & purification*; D009181:Mycoses / Q000175:diagnosis* / Q000188:drug therapy; D010490:Pericardial Effusion / Q000382:microbiology; D014517:Ureteral Obstruction / Q000382:microbiology
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B