title: Free radicals and MPTP-induced selective destruction of substantia nigra compacta neurons.
authors.affiliation: Unit on Neurotoxicology and Neuroprotection, National Institute of Mental Health, Bethesda, Maryland 20892, USA.
authors.forename: C C
authors.initials: CC
authors.lastname: Chiueh
authors.forename: P
authors.initials: P
authors.lastname: Rauhala
mesh_terms: D015655:1-Methyl-4-phenylpyridinium / Q000633:toxicity; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D004298:Dopamine / Q000378:metabolism*; D005609:Free Radicals / Q000378:metabolism; D017665:Hydroxyl Radical / Q000378:metabolism; D020267:MPTP Poisoning; D008543:Melanins / Q000378:metabolism*; D009474:Neurons / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology; D018384:Oxidative Stress / Q000187:drug effects; D016716:PC12 Cells; D051381:Rats; D017382:Reactive Oxygen Species / Q000378:metabolism*; D013378:Substantia Nigra / Q000187:drug effects* / Q000378:metabolism / Q000473:pathology
chemical_list: D000975:Antioxidants; D005609:Free Radicals; D008543:Melanins; D017382:Reactive Oxygen Species; D017665:Hydroxyl Radical; D015655:1-Methyl-4-phenylpyridinium; D004298:Dopamine