title: 3-[2-(Pyrrolidin-1-yl)ethyl]indoles and 3-[3-(piperidin-1-yl)propyl]indoles: agonists for the h5-HT1D receptor with high selectivity over the h5-HT1B subtype.
authors.affiliation: Chemistry Department, Merck Sharp and Dohme Research Laboratories, Harlow, Essex, U.K.
authors.forename: J L
authors.initials: JL
authors.lastname: Castro
authors.forename: L J
authors.initials: LJ
authors.lastname: Street
authors.forename: A R
authors.initials: AR
authors.lastname: Guiblin
authors.forename: R A
authors.initials: RA
authors.lastname: Jelley
authors.forename: M G
authors.initials: MG
authors.lastname: Russell
authors.forename: F
authors.initials: F
authors.lastname: Sternfeld
authors.forename: M S
authors.initials: MS
authors.lastname: Beer
authors.forename: J A
authors.initials: JA
authors.lastname: Stanton
authors.forename: V G
authors.initials: VG
authors.lastname: Matassa
mesh_terms: D006801:Humans; D010880:Piperidines / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D011485:Protein Binding; D011759:Pyrrolidines / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D044302:Receptor, Serotonin, 5-HT1B; D044346:Receptor, Serotonin, 5-HT1D; D011985:Receptors, Serotonin / Q000187:drug effects* / Q000378:metabolism; D011994:Recombinant Proteins / Q000187:drug effects; D017366:Serotonin Receptor Agonists / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*
chemical_list: C470302:HTR1B protein, human; D010880:Piperidines; D011759:Pyrrolidines; D044302:Receptor, Serotonin, 5-HT1B; D044346:Receptor, Serotonin, 5-HT1D; D011985:Receptors, Serotonin; D011994:Recombinant Proteins; D017366:Serotonin Receptor Agonists