Cyfra 21-1 and TPA as markers in malignant mesothelioma.
BACKGROUND
Serum concentrations of CEA and Cyfra were compared in patients with mesothelioma.


METHODS
Serum levels of patients were analysed for prognosis of survival and follow up of disease.


RESULTS
Cyfra 21-1 and TPA have significant prognostic value for survival.


CONCLUSIONS
Assays measuring CK19 fragments seem to be good markers in the management of patients with malignant mesothelioma.
Bonfrer
J M
JM
Department of Clinical Chemistry, The Netherlands Cancer Institute (Antoni van Leeuwenhoek Huis), Amsterdam, The Netherlands.
Schouwink
J H
JH
Korse
C M
CM
Baas
P
P
D000951:Antigens, Neoplasm / Q000097:blood*; D014408:Biomarkers, Tumor / Q000097:blood*; D006801:Humans; D053539:Keratin-19; D007633:Keratins; D008654:Mesothelioma / Q000097:blood* / Q000401:mortality; D015996:Survival Rate; D019396:Tissue Polypeptide Antigen / Q000097:blood*
D000951:Antigens, Neoplasm; D014408:Biomarkers, Tumor; D053539:Keratin-19; D019396:Tissue Polypeptide Antigen; C102012:antigen CYFRA21.1; D007633:Keratins