A significant difference is one that makes a difference.
Todd
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D018686:Anesthetics, Intravenous / Q000037:antagonists & inhibitors; D000931:Antidotes / Q000008:administration & dosage*; D001569:Benzodiazepines / Q000037:antagonists & inhibitors; D002986:Clinical Trials as Topic; D016292:Procedural Sedation / Q000009:adverse effects*; D004635:Emergency Medicine / Q000379:methods*; D004636:Emergency Service, Hospital / Q000592:standards / Q000639:trends; D005442:Flumazenil / Q000008:administration & dosage*; D006801:Humans; D008874:Midazolam / Q000037:antagonists & inhibitors; D010146:Pain / Q000517:prevention & control*; D017410:Practice Guidelines as Topic; D014481:United States
D018686:Anesthetics, Intravenous; D000931:Antidotes; D001569:Benzodiazepines; D005442:Flumazenil; D008874:Midazolam