title: Conservative treatment of hemarthrosis for prevention of hemophilic synovitis.
abstract: Acute hemarthroses are probably the most frequent type of bleeding in the patient with hemophilia. Delayed and/or inadequate treatment can trigger a series of pathologic changes within the joint leading to a painful and disabling arthropathy. Despite the advent of prophylactic treatment with factor concentrates, the majority of patients in the world have no access to even on demand factor replacement. Care for all patients involves a team approach led by the hematologist but including input from orthopaedic surgeons and physiotherapists. Optimal treatment involves a combination of factor replacement, rest, ice, and supervised rehabilitation. In certain cases, joint aspiration may be considered. In developing countries, where factor concentrates are in short supply, such bleeding episodes usually are treated by physical means alone or with the addition of cryoprecipitate or fresh frozen plasma. After successful resolution of such episodes by whatever means, the events leading to the bleeding episode and its subsequent management should be considered within the setting of the treating unit. Such debriefings should aim to provide counsel regarding any appropriate lifestyle modifications and, where necessary, treatment should be arranged to minimize the risk of additional episodes.
authors.affiliation: Department of Orthopaedics, Northampton General Hospital, United Kingdom.
authors.forename: W J
authors.initials: WJ
authors.lastname: Ribbans
authors.forename: P
authors.initials: P
authors.lastname: Giangrande
authors.forename: K
authors.initials: K
authors.lastname: Beeton
mesh_terms: D000208:Acute Disease; D001779:Blood Coagulation Factors / Q000627:therapeutic use; D003376:Counseling; D017679:Cryotherapy; D003906:Developing Countries; D006395:Hemarthrosis / Q000517:prevention & control / Q000534:rehabilitation / Q000628:therapy*; D006467:Hemophilia A / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007053:Ice; D007592:Joint Diseases / Q000209:etiology / Q000517:prevention & control; D008019:Life Style; D019152:Paracentesis; D010348:Patient Care Team; D026741:Physical Therapy Modalities; D012146:Rest; D012307:Risk Factors; D013585:Synovitis / Q000517:prevention & control*
chemical_list: D001779:Blood Coagulation Factors; D007053:Ice