Nucleotide sequence variation of human T-lymphotropic virus type II in Vietnam.
A high rate of human T-lymphotropic virus type II (HTLV-II) infection has been documented in intravenous drug abusers (IVDAs) in South Vietnam. We have investigated the molecular characteristics of the virus and have shown that one HTLV-II subtype is predominant in Ho Chi Minh City. This molecular subtype, HTLV-IIb, was identified in a number of South Vietnamese by nucleotide sequence analysis of the long terminal repeat (LTR) region. HTLV-IIa was not found. These findings suggest that HTLV-IIb is endemic in IVDAs in South Vietnam, although IVDAs in urban areas in North America are predominantly infected with HTLV-IIa.
Yoshizaki
H
H
First Research Group, National Institute of Infectious Diseases, Tokyo.
Nakasone
T
T
Nakasatomi
T
T
Kusagawa
S
S
Sato
H
H
Nguyen
T H
TH
Mai
H A
HA
Hoang
T L
TL
Takebe
Y
Y
Honda
M
M
D000328:Adult; D001483:Base Sequence; D014644:Genetic Variation; D015482:HTLV-II Antibodies / Q000097:blood; D015491:HTLV-II Infections / Q000635:transmission / Q000821:virology*; D015367:Human T-lymphotropic virus 2 / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008969:Molecular Sequence Data; D009656:North America; D010802:Phylogeny; D012091:Repetitive Sequences, Nucleic Acid; D016415:Sequence Alignment; D015819:Substance Abuse, Intravenous; D014505:Urban Population; D014744:Vietnam
D015482:HTLV-II Antibodies