Discoid lupus erythematosus presenting as asymmetric posterior blepharitis.
OBJECTIVE
To describe the ophthalmic findings of patients with discoid lupus erythematosus.


METHODS
We describe two women who originally were thought to have asymmetric posterior blepharitis; however, the involved eyelid also had an erythematous, scaly cutaneous lesion.


RESULTS
In both patients, histology and immunofluorescence studies performed on cutaneous biopsy specimens established the diagnosis of discoid lupus erythematosus.


CONCLUSIONS
It is important to diagnose discoid lupus of the eyelids because misdiagnosis can delay treatment and thus lead to deformities of the eyelid margin. Misdiagnosis can also lead to a complicated full-thickness eyelid biopsy and delay the diagnosis of systemic lupus erythematosus.
Gloor
P
P
Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT 06520-8061, USA. peter.gloor@yale.edu
Kim
M
M
McNiff
J M
JM
Wolfley
D
D
D000328:Adult; D000962:Antimalarials / Q000627:therapeutic use; D001706:Biopsy; D001762:Blepharitis / Q000175:diagnosis* / Q000188:drug therapy; D005143:Eyelids / Q000187:drug effects / Q000473:pathology; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D008179:Lupus Erythematosus, Discoid / Q000175:diagnosis* / Q000188:drug therapy; D008875:Middle Aged
D000962:Antimalarials; D006886:Hydroxychloroquine