title: Echovirus type 22 outbreak associated with gastro-intestinal disease in a neonatal intensive care unit.
abstract: An echovirus type 22 outbreak involving 19 neonatal intensive care unit (NICU) patients during the months of October and November 1992 is reported. Twelve infants presented with diarrhea, 7 of whom had bloody stools and x-ray findings compatible with early stages of necrotizing enterocolitis, while one infant demonstrated characteristic pneumatosis intestinalis. Outbreaks of echovirus type 22 infection in premature infants have rarely been reported. The possibility of Echovirus 22 infection should be considered in neonatal gastrointestinal disease associated with features of necrotizing enterocolitis.
authors.affiliation: Department of Neonatalogy, Chaim Sheba Medical Center, Tel-Hashomer, Israel.
authors.forename: E
authors.initials: E
authors.lastname: Birenbaum
authors.forename: R
authors.initials: R
authors.lastname: Handsher
authors.forename: J
authors.initials: J
authors.lastname: Kuint
authors.forename: R
authors.initials: R
authors.lastname: Dagan
authors.forename: B
authors.initials: B
authors.lastname: Raichman
authors.forename: E
authors.initials: E
authors.lastname: Mendelson
authors.forename: N
authors.initials: N
authors.lastname: Linder
mesh_terms: D000914:Antibodies, Viral / Q000032:analysis; D003428:Cross Infection / Q000453:epidemiology* / Q000821:virology; D004196:Disease Outbreaks; D004457:Echovirus Infections / Q000175:diagnosis / Q000453:epidemiology*; D029822:Enterovirus B, Human / Q000276:immunology; D005767:Gastrointestinal Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000821:virology*; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D007557:Israel
chemical_list: D000914:Antibodies, Viral