title: Principles and methods of evolutionary biotechnology.
abstract: Evolutionary biotechnology applies the principles of molecular evolution to biotechnology, leading to novel techniques for the creation of biomolecules with a great variety of functions for technical and medical purposes. Several basic principles for the application of evolutionary strategies can be derived from a comprehensive theory of molecular evolution. Prerequisites for evolutionary biotechnology are summarized with respect to the different classes of biomolecules and a few, selected applications are described in detail. Concepts for the technical implementation of evolutionary strategies are presented which allow automatized, high throughput processes.
authors.affiliation: Max-Planck-Institut für biophysikalische Chemie, Abteilung Biochemische Kinetik, Göttingen, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Koltermann
authors.forename: U
authors.initials: U
authors.lastname: Kettling
mesh_terms: D001709:Biotechnology / Q000379:methods*; D019143:Evolution, Molecular