title: Ribozymes, recognition and evolution.
abstract: Precision in the recognition and orientation of substrate is important in the selectivity of catalysis by natural enzymes. Several new ribozyme species have been evolved using in vitro selection/mutagenesis which make use of precise substrate recognition to catalyze a variety of reactions.
authors.affiliation: Department of Chemistry and Biochemistry, University of Texas, Austin 78712, USA.
authors.forename: B L
authors.initials: BL
authors.lastname: Iverson
mesh_terms: D000818:Animals; D005075:Biological Evolution; D002384:Catalysis; D006801:Humans; D012313:RNA / Q000096:biosynthesis; D016337:RNA, Catalytic / Q000502:physiology*
chemical_list: D016337:RNA, Catalytic; D012313:RNA