Capsaicin stimulates release of substance P from dorsal root ganglion neurons via two distinct mechanisms.
Purkiss
J R
JR
CAMR (Centre of Applied Microbiology and Research), Salisbury, Wiltshire, U.K.
Welch
M J
MJ
Doward
S
S
Foster
K A
KA
D000818:Animals; D019274:Botulinum Toxins, Type A / Q000494:pharmacology; D002118:Calcium / Q000494:pharmacology; D002211:Capsaicin / Q000494:pharmacology*; D002478:Cells, Cultured; D004533:Egtazic Acid / Q000494:pharmacology; D004622:Embryo, Mammalian; D005727:Ganglia, Spinal / Q000166:cytology / Q000502:physiology*; D007700:Kinetics; D009474:Neurons / Q000166:cytology / Q000187:drug effects / Q000502:physiology*; D011189:Potassium Chloride / Q000494:pharmacology; D051381:Rats; D013373:Substance P / Q000378:metabolism*
D013373:Substance P; D004533:Egtazic Acid; D011189:Potassium Chloride; D019274:Botulinum Toxins, Type A; D002211:Capsaicin; D002118:Calcium