The lom gene of bacteriophage lambda is involved in Escherichia coli K12 adhesion to human buccal epithelial cells.
The role of the lom gene of bacteriophage lambda in adhesion of Escherichia coli to human buccal epithelial cells (HBC) was studied testing the adherence of lamda lom+ and lambda lom::TnphoA E. coli lysogens. lambda lom+ prophage increased 50% E. coli adhesion. This effect was not observed with lambda lom::TnphoA. These results suggest that the normal Lom protein participates directly in adhesion or regulates the synthesis of other protein(s), which may be involved in adhesion.
Vica Pacheco
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Laboratorio de Genética, Escuela Nacional de Estudios Profesionales Iztacala, Universidad Nacional Autónoma de México, Tlalnepantla, Edo., Mexico.
García González
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Paniagua Contreras
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GL
D000328:Adult; D001422:Bacterial Adhesion / Q000235:genetics*; D001425:Bacterial Outer Membrane Proteins / Q000235:genetics*; D010582:Bacteriophage lambda / Q000235:genetics*; D002610:Cheek / Q000382:microbiology; D004847:Epithelial Cells / Q000382:microbiology; D004926:Escherichia coli / Q000235:genetics* / Q000472:pathogenicity* / Q000821:virology; D005814:Genes, Viral; D006801:Humans; D066298:In Vitro Techniques; D014764:Viral Proteins; D014774:Virulence / Q000235:genetics
D001425:Bacterial Outer Membrane Proteins; D014764:Viral Proteins; C065502:lambdap26 protein, Bacteriophage lambda