title: [Diphasic regulatory effect of lishen injection on sex hormones in senile female patients with coronary heart disease of kidney deficiency type].
abstract: Effects of Lishen injection on serum estradiol (E2), testosterone (T) and the E2/T ratio in 30 cases of postmenopausal patients with coronary heart disease and of Kidney Deficiency type were observed. Results showed that: (1) Serum E2 and the E2/T ratio were lower (P < 0.01) in the group of Kidney-Yin Deficiency type and higher (P < 0.01) in the group of Kidney-Yang Deficiency type as compared with normal control. (2) After treatment with Lishen injection the levels of serum E2 and the E2/T ratio were elevated in the former (P < 0.01) and lowered in the later (P < 0.01). Both were approaching to normal level (P > 0.05). (3) The levels of T in both groups were unaffected (P > 0.05) before and after treatment. These results suggested the imbalance of Kidney-Yin and Kidney-Yang is related to the disturbance of sex hormones and Lishen injection could not only regulate the Kidney-Yin and Kidney-Yang, improve the symptoms of Kidney Deficiency, but also could convert the abnormal change of sex hormone, it has a good diphasic regulatory effect on E2, and is beneficial on balance of sex hormones of both sex in the inner environment of human body.
authors.affiliation: First affiliated Hospital, Sun Yat-sen University of Medical Sciences, Guangzhou.
authors.forename: R X
authors.initials: RX
authors.lastname: Qiu
authors.forename: M H
authors.initials: MH
authors.lastname: Jin
authors.forename: G Z
authors.initials: GZ
authors.lastname: Wu
mesh_terms: D000368:Aged; D003327:Coronary Disease / Q000097:blood* / Q000188:drug therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004958:Estradiol / Q000097:blood*; D005260:Female; D006801:Humans; D008875:Middle Aged; D005894:Panax; D010946:Plants, Medicinal; D017698:Postmenopause; D013739:Testosterone / Q000097:blood*; D016711:Yang Deficiency / Q000097:blood / Q000188:drug therapy; D016710:Yin Deficiency / Q000097:blood / Q000188:drug therapy
chemical_list: D004365:Drugs, Chinese Herbal; D013739:Testosterone; D004958:Estradiol