title: Non-Hodgkin lymphoma (NHL) as a second neoplasm occurring after neuroblastoma treatment.
abstract: As far as we know, this is the first report of a non-Hodgkin lymphoma developing after successful treatment of neuroblastoma. A boy was found to have a mediastinal T-cell lymphoma at the age of 5. He had been treated for a neuroblastoma of the left adrenal region 4 years before, when by intensive chemotherapy and radiation a complete remission of the primary tumor was achieved. The second malignancy has also been controlled without evidence of recurrence 1 year after termination of treatment. We conclude that treatment of a neuroblastoma by cytostatic drugs and radiation may lead to a non-Hodgkin lymphoma as a second malignancy.
authors.affiliation: Department of Pediatrics, Medical Faculty of the Technical University, Dresden, Germany.
authors.forename: E
authors.initials: E
authors.lastname: Siegert
authors.forename: G
authors.initials: G
authors.lastname: Weissbach
authors.forename: R
authors.initials: R
authors.lastname: Fischer
authors.forename: I
authors.initials: I
authors.lastname: Lauterbach
mesh_terms: D006801:Humans; D007223:Infant; D008228:Lymphoma, Non-Hodgkin / Q000209:etiology*; D008297:Male; D016609:Neoplasms, Second Primary / Q000209:etiology*; D009447:Neuroblastoma / Q000628:therapy*