[Relationship between lipid peroxidase and superoxide dismutase in bronchoalveolar lavage fluid and pulmonary qi deficiency syndrome].
Investigating the levels of lipid peroxidase (LPO) and superoxide dismutase (SOD) in serum, bronchoalveolar lavage fluid (BALF) and alveolar macrophage (AM) were determined in 40 chronic bronchitis patients with Pulmonary Qi Deficiency (PQD) Syndrome and 36 normal subjects. Results showed: (1) No significant differences were found between PQD syndrome and normal subjects on serum SOD or LPO levels. (2) Patients with PQD Syndrome. LPO level in BALF was significantly higher, and SOD significantly lower, when compared with normal subjects. (3) Through correlation analysis, it was found in BALF that SOD level was markedly correlated with AM, while LPO was significantly correlated with neutrophil. In short, SOD and LPO in BALF play an important role in the development of the PQD Syndrome, and are good indications in evaluating the PQD Syndrome.
Zhao
J Y
JY
Anhui College of TCM, Hefei.
Song
W D
WD
Liu
Z B
ZB
D000328:Adult; D000368:Aged; D001991:Bronchitis / Q000201:enzymology*; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry*; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation; D016676:Macrophages, Alveolar / Q000201:enzymology; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D019413:Qi; D013482:Superoxide Dismutase / Q000378:metabolism*
D013482:Superoxide Dismutase