title: Antibiotic-impregnated cement beads in the treatment of chronic osteomyelitis.
abstract: Fifty-four patients with chronic osteomyelitis of the long bones were treated at Gyeong-Sang National University Hospital between 1985 and 1993 using the cement bead technique. We studied the results of thirty-one patients who were followed up for 3 years or more. The average duration of follow-up was 4 years and 2 months (range: 3 to 7 years). All of the patients were treated by a two-stage operation; primary saucerization with implantation of antibiotic-impregnated polymethylmethacrylate beads and secondary bone grafts. The most recent follow-up examinations and analyses revealed that 17 patients (55%) were completely free of infection. Ten patients (32%) required repeated procedures of curettage and/or bone grafting. Amputations were performed on 4 patients.
authors.affiliation: Department of Orthopaedic Surgery College of Medicine and Hospital, Gyeong-Sang National University, Chinju, South Korea.
authors.forename: S H
authors.initials: SH
authors.lastname: Cho
authors.forename: H R
authors.initials: HR
authors.lastname: Song
authors.forename: K H
authors.initials: KH
authors.lastname: Koo
authors.forename: S T
authors.initials: ST
authors.lastname: Jeong
authors.forename: Y J
authors.initials: YJ
authors.lastname: Park
mesh_terms: D000293:Adolescent; D000328:Adult; D000671:Amputation, Surgical; D000900:Anti-Bacterial Agents; D001843:Bone Cements / Q000627:therapeutic use*; D016025:Bone Transplantation; D002908:Chronic Disease; D003131:Combined Modality Therapy; D003646:Debridement; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008863:Microspheres; D008875:Middle Aged; D010019:Osteomyelitis / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery*; D019904:Polymethyl Methacrylate / Q000627:therapeutic use*; D011859:Radiography; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D001843:Bone Cements; D019904:Polymethyl Methacrylate