title: Minimization of the number of pregnant women to be treated with preventive procedure against GBS infection by means of antibody measurement. GBS Infection Group.
abstract: To study preventive strategies, it is essential to screen pregnant women having group B Streptococcus (GBS) infection in the birth canal. For the purpose of studying preventive measures against this infection, nationwide multicenter research was performed in GBS-carrying pregnant women. Of a total of 10,267 pregnant women, 1860 cases (18.1%) had GBS. The most common serotypes of detected GBS were type NT6 and JM9, followed by type III, type Ia and then type Ib. Type-specific antibody titer was below the cut-off point of 10 units/mL in 30.9% of Ia carriers, 58.5% of Ib carriers, 45.9% of II carriers and 32.9% of III carriers. Fortunately, no neonatal GBS infection occurred during this research. We concluded that 18.1% of studied pregnant women were GBS carriers and one-third of these GBS carriers required preventive procedures with antibody measurement.
authors.affiliation: Tokyo Teishin Hospital, Fujimi, Chiyoda-ku, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Hoshina
mesh_terms: D000907:Antibodies, Bacterial / Q000032:analysis*; D002353:Carrier State / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical / Q000517:prevention & control*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis*; D013290:Streptococcal Infections / Q000175:diagnosis* / Q000517:prevention & control*; D013292:Streptococcus agalactiae / Q000276:immunology
chemical_list: D000907:Antibodies, Bacterial