[New use of Bletilla striata as embolizing agent in the intervention treatment of hepatic carcinoma].
A Chinese herb, Bletilla striata, was used as embolizing agent in order to improve the therapeutic results of intervention treatment of liver cancer. From October 1991 to January 1995, 56 cases of hepatic carcinoma were treated with Bletilla striata by hepatic artery embolization, with conventional gelform embolization in 50 cases as control. Patients were followed-up for 10-48 months. Embolization with Bletilla striata led to extensive and permanent vascular obstruction, accompanied with marked shrinkage of tumor size and significant decrease in serum AFP levels. Collaterals were few in number and collateral circulation was established late so that the treatment intervals could be prolonged, with an average of 7 months. The 1-, 2-, and 3-year survival rate was 81.9%, 44.9% and 33.6%, respectively, with a median survival time of 19.8 months. All the clinical parameters were better than those treated with conventional gelform embolization. The results indicate that Bletilla striata is an ideal vascular embolizing agent.
Zheng
C
C
Department of Radiology, Union Hospital of Tongji Medical University, Wuhan.
Feng
G
G
Zhou
R
R
D000328:Adult; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D004621:Embolization, Therapeutic; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008113:Liver Neoplasms / Q000097:blood / Q000401:mortality / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D015641:Radiography, Interventional; D015996:Survival Rate; D000509:alpha-Fetoproteins / Q000032:analysis
D004365:Drugs, Chinese Herbal; D000509:alpha-Fetoproteins