Principles and methods of evolutionary biotechnology.
Evolutionary biotechnology applies the principles of molecular evolution to biotechnology, leading to novel techniques for the creation of biomolecules with a great variety of functions for technical and medical purposes. Several basic principles for the application of evolutionary strategies can be derived from a comprehensive theory of molecular evolution. Prerequisites for evolutionary biotechnology are summarized with respect to the different classes of biomolecules and a few, selected applications are described in detail. Concepts for the technical implementation of evolutionary strategies are presented which allow automatized, high throughput processes.
Koltermann
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A
Max-Planck-Institut für biophysikalische Chemie, Abteilung Biochemische Kinetik, Göttingen, Germany.
Kettling
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U
D001709:Biotechnology / Q000379:methods*; D019143:Evolution, Molecular