title: Site-specific recombination: synapsis and strand exchange revealed.
abstract: Recently determined crystal structures of several members of the lambda integrase family of site-specific recominases have provided insights into the cis versus trans action of active site constituents, and hte processes of synapsis and strand exchange.
authors.affiliation: Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520-8114, USA.
authors.forename: N D
authors.initials: ND
authors.lastname: Grindley
mesh_terms: D001665:Binding Sites; D004254:DNA Nucleotidyltransferases / Q000737:chemistry / Q000378:metabolism*; D019426:Integrases / Q000737:chemistry / Q000378:metabolism*; D045522:Recombinases; D011995:Recombination, Genetic; D013329:Structure-Activity Relationship
chemical_list: D045522:Recombinases; D004254:DNA Nucleotidyltransferases; D019426:Integrases; C115006:integron integrase IntI1