Molecular motors: the natural economy of kinesin.
Kinesin is a molecular-scale walking machine. New analyses of its mechanism indicate that each step along a microtubule consumes one ATP molecule, and that the binding and cleavage of ATP precede detachment of the molecule's 'feet'. Directional walking ensues if ATP processing occurs preferentially on one foot.
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Molecular Motors Group, Marie Curie Research Institute, Oxted, Surrey, UK.
D000251:Adenosine Triphosphatases / Q000378:metabolism; D000255:Adenosine Triphosphate / Q000378:metabolism*; D016547:Kinesins / Q000378:metabolism / Q000502:physiology*; D008870:Microtubules / Q000378:metabolism
D000255:Adenosine Triphosphate; D000251:Adenosine Triphosphatases; D016547:Kinesins