Extended duration between harvest and re-infusion of human bone marrow stored at room temperature.
A major limitation of unrelated bone marrow transplantation is the duration of time that is safe between harvest and re-infusion of the marrow. We have been able to demonstrate safe re-infusion of bone marrow kept at room temperature during transport, after almost 36 h. In vitro colony-forming assays suggest that stability may be as long as 5 days.
Lipton
J H
JH
Department of Medicine, Princess Margaret Hospital/Ontario Cancer Institute, University of Toronto, Canada.
Jamal
N
N
Messner
H A
HA
D000328:Adult; D001800:Blood Specimen Collection / Q000379:methods*; D016026:Bone Marrow Transplantation; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000628:therapy; D008297:Male; D013048:Specimen Handling / Q000379:methods; D013696:Temperature; D013997:Time Factors