title: [Methylene blue staining in fiberoptic bronchoscopy in the diagnosis of bronchial tumors].
abstract: 47 patients were stained by using methylene blue in fiberoptic bronchoscopy. Of these, 35 had central lung cancer, and 12 bronchitis. 40 patients with central lung cancer were detected by general fibreoptic endoscopy. The results demonstrated that normal bronchial mucosa was not stained, 97.14% central malignant bronchial tumors stained, and 8.33% bronchitis stained. X2test showed the marked difference. Positive diagnosis was 97.06% in biopsy specimens stained, it was higher than 77.05% in the general investigated (P < 0.05). Using methylene blue in fiberoptic bronchoscopy would help diagnose central lung cancer, determine tumors limits, permit accurate biopsy. The stain was not related to the pathological classification, differentiation of cancer cells, and classification of clinical pathology (P > 0.05).
authors.affiliation: Second Hospital, China Medical University, Shenyang.
authors.forename: R
authors.initials: R
authors.lastname: Yang
authors.forename: X
authors.initials: X
authors.lastname: Yin
authors.forename: X
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000328:Adult; D000368:Aged; D001984:Bronchial Neoplasms / Q000175:diagnosis*; D001999:Bronchoscopy; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis*; D004396:Coloring Agents; D005260:Female; D006801:Humans; D008297:Male; D008751:Methylene Blue; D008875:Middle Aged; D013194:Staining and Labeling
chemical_list: D004396:Coloring Agents; D008751:Methylene Blue