title: A comparison of arc-based and static mini-multileaf collimator-based radiosurgery treatment plans.
abstract: BACKGROUND
  The purpose of this study is to compare arc-based and mini-multileaf collimator (mMLC)-based radiosurgery treatment plans using isodose distributions and dose-volume histograms.
  
  
  METHODS
  Of 11 patients who underwent conventional arc-based radiosurgery for intracranial malignancies, four were treated with one isocenter, four were treated with two isocenters and three were treated with three isocenters. The same cases were re-planned using a test version of mMLC-based radiosurgery software for multiple static non-coplanar fields.
  
  
  CONCLUSIONS
  For non-spherical targets, treatment planning is relatively intuitive with mMLC-based radiosurgery, reducing the amount of time required for planning. Moreover, a lower dose of radiation is delivered to normal tissue with mMLC-based radiosurgery than with arc-based radiosurgery, which theoretically should lead to a reduced risk of complications.
authors.affiliation: Department of Radiation Oncology, University of California, Davis Medical Center, Sacramento 95817, USA.
authors.forename: H D
authors.initials: HD
authors.lastname: Kubo
authors.forename: C T
authors.initials: CT
authors.lastname: Pappas
authors.forename: R B
authors.initials: RB
authors.lastname: Wilder
mesh_terms: D001932:Brain Neoplasms / Q000601:surgery*; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D011379:Prognosis; D011829:Radiation Dosage; D016634:Radiosurgery / Q000295:instrumentation / Q000379:methods*; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*