[Methotrexate and pregnancy].
A 39-year-old woman had a spontaneous abortion at the 13th-14th gestational week. Not knowing that she was pregnant, she had taken two doses of methotrexate of 15 mg for psoriasis--one dose at the conception time and one dose a week later. Autopsy of the foetus revealed no malformations. Guidelines for low-dose methotrexate treatment before and after conception are discussed.
Ibsen
H H
HH
Arhus Universitetshospital, Marselisborg Hospital, dermato-venerologisk afdeling.
D000022:Abortion, Spontaneous / Q000139:chemically induced*; D000328:Adult; D003879:Dermatologic Agents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects*; D011247:Pregnancy; D011565:Psoriasis / Q000188:drug therapy
D003879:Dermatologic Agents; D008727:Methotrexate