title: Poland's syndrome and Wilms tumor: an unusual association.
abstract: Poland's syndrome, a rare congenital disorder with pectoralis muscular girdle defect, have been reported in association with lymphoreticular malignancies in the past. Childhood solid tumors in association with this congenital anomaly have not been reported so far. We describe this rare association of Poland's syndrome and Wilms tumor. Due to the possibility of increased risk of leukemogenesis in patients with Poland's syndrome, chemo-radiation therapy of Wilms tumor in our patient may increase the risk of secondary leukemia. Therapeutic modification of primary cancer in these patients may be necessary with careful long-term follow-up for early detection and treatment of secondary cancer.
authors.affiliation: Department of Pediatric Hematology/Oncology, Louisiana State University School of Medicine and Children's Hospital, New Orleans 70118, USA.
authors.forename: U H
authors.initials: UH
authors.lastname: Athale
authors.forename: R
authors.initials: R
authors.lastname: Warrier
mesh_terms: D006801:Humans; D007223:Infant; D007680:Kidney Neoplasms / Q000150:complications*; D008297:Male; D011045:Poland Syndrome / Q000150:complications*; D009396:Wilms Tumor / Q000150:complications*