Expression of CD34 in glomus tumors.
Immunohistochemical studies were performed in order to characterize glomus tumors. In all cases the glomus tumor cells stained positively for smooth muscle actin. In half of six cases, the glomus tumor cells weakly expressed desmin. They were not reactive with Ulex europaeus agglutinin-I and anti-Factor VIII-related antigen, whereas the only endothelial cells were reactive with them. The tumor cells as well as vascular endothelial cells amongst the tumor cells expressed CD34 in five of the cases.
Hatori
M
M
Department of Orthopaedic Surgery, Tohoku University School of Medicine, Japan.
Aiba
S
S
Kato
M
M
Kamiya
N
N
Kokubun
S
S
D000293:Adolescent; D000328:Adult; D018952:Antigens, CD34 / Q000032:analysis / Q000096:biosynthesis*; D014408:Biomarkers, Tumor / Q000032:analysis; D005385:Fingers; D005918:Glomus Tumor / Q000737:chemistry / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D009260:Nail Diseases / Q000378:metabolism / Q000473:pathology*; D014034:Toes
D018952:Antigens, CD34; D014408:Biomarkers, Tumor