Primary malignant melanoma of the conjunctiva of the upper eyelid. A case report.
BACKGROUND
Malignant melanoma of the conjunctiva is rare. The nomenclature and clinical and pathologic features of cutaneous and conjunctival melanomas are different.


METHODS
A 62-year-old male presented with a history of slight bleeding of the upper conjunctiva for the previous six months. On clinical examination the ophthalmologist observed a smooth, partly nodular, pigmented lesion on the conjunctiva under the left eyelid, 1.5 cm in diameter. Fine needle aspiration (FNA) biopsy of the mass showed tumor cells dispersed as single cells with eccentric, round nuclei; coarsely granular chromatin; prominent nucleoli; and dense cytoplasm with occasional brownish pigmentation as well as small aggregates of spindle-shaped neoplastic cells with hyperchromatic nuclei and no cytoplasmic pigment.


CONCLUSIONS
FNA cytology is a simple and efficient method of making the diagnosis of malignant melanoma in conjunctival masses. Careful correlation with the clinical history and histologic findings is often necessary for confirmation of the diagnosis.
Gonidi
M
M
General Hospital of Corfu, Athens, Greece.
Athanassiadou
P
P
Drazinos
S
S
Petrakakou
E
E
Kairis
M
M
Zerva
C
C
D001707:Biopsy, Needle; D002466:Cell Nucleolus / Q000473:pathology; D002467:Cell Nucleus / Q000473:pathology; D002843:Chromatin / Q000473:pathology; D003230:Conjunctival Neoplasms / Q000473:pathology* / Q000601:surgery; D003593:Cytoplasm / Q000473:pathology; D005142:Eyelid Neoplasms / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D008545:Melanoma / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged
D002843:Chromatin