title: Bioplastique at 6 years: clinical outcome studies.
abstract: Bioplastique is a biphasic polymer for the permanent augmentation of some soft tissues. It was developed in 1987, and clinical studies at this institution were begun in 1990. The combination of low molecular weight polyvinylpyrrolidone and solid polymer particles allows the implantation of permanent polymer spheres through a small needle under local anesthesia. In this study 127 cases are reviewed of consecutive patients who have received Bioplastique for scar revision, wrinkles, and augmentation for soft-tissue defects at 6 years after application. All patients who had not been in for follow-up recently were contacted by mail and questioned on the permanence of augmentation and migration of particles. About 30 percent of the patients were unreachable and had their charts reviewed for permanence and migration of particles. In eight of these cases, Bioplastique was removed because of overcorrection, two of them may have had infection. Bioplastique has gained wide use throughout the world and although some complications have been reported, in general, it functions quite well when used in selected cases.
authors.forename: R A
authors.initials: RA
authors.lastname: Ersek
authors.forename: S R
authors.initials: SR
authors.lastname: Gregory
authors.forename: A V
authors.initials: AV
authors.lastname: Salisbury
mesh_terms: D000328:Adult; D000772:Anesthesia, Local; D001672:Biocompatible Materials / Q000737:chemistry; D002921:Cicatrix / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D005548:Foreign-Body Migration / Q000209:etiology; D006801:Humans; D008970:Molecular Weight; D009339:Needles; D010316:Particle Size; D011108:Polymers / Q000737:chemistry; D011205:Povidone / Q000737:chemistry; D019736:Prostheses and Implants; D019919:Prosthesis Implantation / Q000009:adverse effects / Q000379:methods; D016459:Prosthesis-Related Infections; D019651:Plastic Surgery Procedures / Q000009:adverse effects / Q000379:methods; D012086:Reoperation; D012189:Retrospective Studies; D015361:Rhytidoplasty; D015595:Skin Aging; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D001672:Biocompatible Materials; C068018:Bioplastique; D011108:Polymers; D011205:Povidone