title: [Fluconazole in meningeal coccidioidomycosis].
abstract: We report our experience with ten virgin cases (5 children, 5 adults) with coccidioidal meningitis treated with fluconazole. The diagnosis was confirmed by a positive culture of the cerebrospinal fluid. Fluconazole at doses of 6/mg/kg/day for children and 400 mg/day for adults were given. All responded well, in five it was discontinued and four relapsed but responded well to fluconazole. We conclude that fluconazole is useful for coccidioidal meningitis.
authors.affiliation: Servicios de Infectología, Instituto Mexicano del Seguro Social, Monterrey, N.L.
authors.forename: J J
authors.initials: JJ
authors.lastname: Ayala-Gaytán
authors.forename: B A
authors.initials: BA
authors.lastname: Condarco-Cortés
authors.forename: J A
authors.initials: JA
authors.lastname: Pérez-Zuno
authors.forename: P
authors.initials: P
authors.lastname: Moreno-Guevara
mesh_terms: D000293:Adolescent; D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003047:Coccidioidomycosis / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000188:drug therapy*; D004341:Drug Evaluation; D005260:Female; D015725:Fluconazole / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D016921:Meningitis, Fungal / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000188:drug therapy*; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D015725:Fluconazole