[A histopathologic study on recovering effect of kangdu shengxue decoction on spleen and thymus of mice with radiation injury].
The effect of Kangdu Shengxue Decoction (KDSXD) on the spleen and thymus of mice irradiated with 80Co gamma-rays has been studied by histopathological methods. 130 LACA mice were divided into 3 groups. Control and experimental groups were generally irradiated for once with 8 Gy 80Co gamma-rays. The experiment of group were treated with KDSXD one hour before irradiation and consecutively five days after radiation. The results of experiment showed that 30 days after irradiation the structure of spleen and thymus of treated mice normalized. The difference of recovery between control and experimental group showed a high significance statistically (P < 0.01).
Wang
L Y
LY
Department of Pathology, Guanganmen Hospital, China Academy of Traditional Chinese Medicine, Beijing.
Wu
Z Y
ZY
Zhang
X Y
XY
D000818:Animals; D003037:Cobalt Radioisotopes; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D008297:Male; D051379:Mice; D011833:Radiation Injuries, Experimental / Q000188:drug therapy* / Q000473:pathology*; D011837:Radiation-Protective Agents / Q000627:therapeutic use*; D013154:Spleen / Q000473:pathology*; D013950:Thymus Gland / Q000473:pathology*; D014916:Whole-Body Irradiation
D003037:Cobalt Radioisotopes; D004365:Drugs, Chinese Herbal; D011837:Radiation-Protective Agents