title: [A case of hepatic arterial infusion chemotherapy for multiple liver metastasis from breast cancer].
abstract: A 52-year-old woman underwent Auchinclass' operation for breast cancer. The histological type was papillotubular carcinoma. One year and 5 months after operation, multiple liver tumors were found on the CT scan and multiple bone metastasis on MRI. The former were treated by hepatic artery infusion chemotherapy with epirubicin and 5-FU using a subcutaneous implanted pump and the latter by 50 Gy irradiation. The patient began to complain of abdominal pain and discomfort after hepatic artery infusion, so all treatment was discontinued. Six months later the patient died of respiratory failure due to pleural dissemination. No liver mass was detected, and bone metastasis was not changed in section tissues. This suggested that the therapy for a breast cancer patient with distant metastasis must be considered according to the region of recurrence.
authors.affiliation: First Dept. of Surgery, Nagasaki University, School of Medicine.
authors.forename: S
authors.initials: S
authors.lastname: Hara
authors.forename: S
authors.initials: S
authors.lastname: Hashizume
authors.forename: N
authors.initials: N
authors.lastname: Itoyanagi
authors.forename: H
authors.initials: H
authors.lastname: Ayabe
authors.forename: Y
authors.initials: Y
authors.lastname: Tagawa
authors.forename: H
authors.initials: H
authors.lastname: Tsuji
authors.forename: T
authors.initials: T
authors.lastname: Oka
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
authors.forename: H
authors.initials: H
authors.lastname: Shinguu
authors.forename: K
authors.initials: K
authors.lastname: Tou
authors.forename: H
authors.initials: H
authors.lastname: Tooyama
authors.forename: K
authors.initials: K
authors.lastname: Yamazumi
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000532:radiotherapy / Q000556:secondary*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000556:secondary; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D003131:Combined Modality Therapy; D004334:Drug Administration Schedule; D015251:Epirubicin / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000532:radiotherapy / Q000556:secondary*; D008408:Mastectomy; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000556:secondary
chemical_list: D015251:Epirubicin; D005472:Fluorouracil