Mitochondrial morphogenesis: fusion factor for fly fertility.
The Drosophila Fzo protein is required for mitochondrial fusion during a key step in sperm formation. This novel, membrane-bound GTPase defines a family of proteins that may mediate mitochondrial fusion in a variety of eukaryotic cells.
Yaffe
M P
MP
Department of Biology, University of California, San Diego, La Jolla, California 92093-0347, USA. myaffe@ucsd.edu
D000818:Animals; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000502:physiology*; D005298:Fertility / Q000502:physiology; D020558:GTP Phosphohydrolases / Q000235:genetics / Q000502:physiology*; D006160:Guanosine Triphosphate / Q000378:metabolism; D006801:Humans; D019476:Insect Proteins / Q000235:genetics / Q000502:physiology*; D008297:Male; D008561:Membrane Fusion; D008565:Membrane Proteins / Q000235:genetics / Q000502:physiology*; D008928:Mitochondria / Q000502:physiology*; D009024:Morphogenesis; D013091:Spermatogenesis / Q000502:physiology*
D029721:Drosophila Proteins; D019476:Insect Proteins; D008565:Membrane Proteins; D006160:Guanosine Triphosphate; C107312:Fzo protein, Drosophila; D020558:GTP Phosphohydrolases