Circadian regulation of Fos-like expression in the brain of the blow fly Calliphora vicina.
Expression of Fos-like immunoreactivity (FOS-lir) was examined in the brains of the blow fly Calliphora vicina for evidence of circadian regulation by photic stimuli. Fos-lir in various parts of the brain was investigated as a function of light and time of day. Immunohistochemistry demonstrated that photic stimuli have an inductive effect on c-fos expression in the various parts of the brain, but only in the neurons of the pars intercerebralis did the clear photic induction of c-fos expression occur at times when light was capable of phase-shifting circadian locomotor activity rhythms. This suggests that the c-fos gene may play a role in the photic pathway for circadian entrainment and that these neurons may be involved in the transduction of photic signals. Whether changes in c-fos expression are essential components of this pathway remains to be determined.
Cymborowski
B
B
Department of Invertebrate Physiology, Warsaw University, Poland. bron@asp.biogeo.uw.edu.pl
King
V
V
D000818:Animals; D001921:Brain / Q000166:cytology / Q000502:physiology*; D002940:Circadian Rhythm / Q000235:genetics / Q000502:physiology*; D004175:Diptera / Q000502:physiology*; D005786:Gene Expression Regulation / Q000235:genetics*; D016762:Genes, fos / Q000235:genetics* / Q000276:immunology; D007150:Immunohistochemistry; D008027:Light; D008124:Locomotion; D009474:Neurons / Q000378:metabolism; D015398:Signal Transduction