Thiocoraline, a novel depsipeptide with antitumor activity produced by a marine Micromonospora. II. Physico-chemical properties and structure determination.
Thiocoraline (1) is a new antitumor antibiotic isolated from the mycelium of Micromonospora sp. L-13-ACM2-092. Its structure was elucidated to be a novel cyclic thiodepsipeptide on the basis of spectroscopic methods.
Perez Baz
J
J
Drug Discovery Division, PharmaMar S.A., Spain.
Cañedo
L M
LM
Fernández Puentes
J L
JL
Silva Elipe
M V
MV
D000900:Anti-Bacterial Agents / Q000737:chemistry*; D000903:Antibiotics, Antineoplastic / Q000737:chemistry*; D047630:Depsipeptides; D015394:Molecular Structure; D010455:Peptides
D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; D047630:Depsipeptides; D010455:Peptides; C109005:thiocoraline