title: Heart surgery and quality of life: a prospective study on ischemic patients.
abstract: OBJECTIVE
  Recently, an interest has developed in the use of quality of life instruments to provide a more comprehensive assessment of the impact of disease and treatments on patients' everyday lives over time, particularly in the cardiovascular field. To evaluate changes in quality of life of patients with a coronary heart disease and undergoing heart surgery and to identify patients on which to concentrate stronger rehabilitative intervention, an observational prospective study with repeated measurements has been designed.
  
  
  METHODS
  A total of 259 consecutive coronary heart disease patients (211 males, 48 females, aged 63 (S.D., 9 years) are included into the study. Quality of life has been assessed by means of Karnofsky Performance Status Scale and Nottingham Health Profile (6 dimensions of quality of life) preoperatively, at 2 and 6 months. Changes in quality of life scores at short and mid term and the influence of possible predictors have been investigated. Separate scores have been considered for each dimension of quality of life as well as a global statistics accounting for the multidimensionality of quality of life.
  
  
  RESULTS
  Quality of life increased by 57, 64, 72, 52, 23, 44 and 56% for Karnofsky Performance Status Scale, energy, pain, emotion, sleep, social and mobility respectively at 2 months; at 6 months a further increase of 18% in sleep only occurred. Global scores appeared to be significantly influenced by sex, age class, preoperative NYHA, type of angina, associated procedure and complication at surgery.
  
  
  CONCLUSIONS
  The increase of quality of life concentrates mainly at an early stage of post-operative period. The preoperative factors tested, allow to stratify patients based on quality of life and to identify those on which to concentrate stronger rehabilitative intervention.
authors.affiliation: Biometric Unit-Scientific Direction, IRCCS San Matteo Hospital, Pavia, Italy. bibliosm@mbox.medit.it
authors.forename: C
authors.initials: C
authors.lastname: Klersy
authors.forename: L
authors.initials: L
authors.lastname: Collarini
authors.forename: M C
authors.initials: MC
authors.lastname: Morellini
authors.forename: F
authors.initials: F
authors.lastname: Cellino
mesh_terms: D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000523:psychology* / Q000534:rehabilitation / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011788:Quality of Life; D013997:Time Factors