Respiratory-related pharyngeal constrictor muscle activity in decerebrate cats.
Respiratory-related activity of the hyopharyngeus (middle pharyngeal constrictor) and thyropharyngeus (inferior pharyngeal constrictor) muscles was determined in decerebrate, tracheotomized adult cats and compared with the electromyographic activity of the thyroarytenoid, a vocal cord adductor. During quiet breathing, the hyopharyngeus and usually the thyroarytenoid exhibited phasic activity during expiration and tonic activity throughout the respiratory cycle. Respiratory-related thyropharyngeus activity was absent under these conditions. Progressive hyperoxic hypercapnia and progressive isocapnic hypoxia increased phasic expiratory activity in both pharyngeal constrictor (PC) muscles but tended to suppress thyroarytenoid activity. Passively induced hypocapnia and the central apnea that followed the cessation of the mechanical hyperventilation were associated with tonic activation of the hyopharyngeus and thyroarytenoid but no recruitment in thyropharyngeus activity. The expiratory phase of a sigh and progressive pneumothorax were associated with an increase in phasic thyroarytenoid activity but no change in phasic PC activity. The results indicate that a variety of stimuli modulate respiratory-related PC activity, suggesting that the PC muscles may have a role in the regulation of upper airway patency during respiration.
Kuna
S T
ST
Department of Internal Medicine, University of Texas Medical Branch, Galveston 77555-0561, USA.
Vanoye
C R
CR
D000818:Animals; D002415:Cats; D003655:Decerebrate State / Q000503:physiopathology*; D004576:Electromyography; D005260:Female; D006935:Hypercapnia / Q000503:physiopathology; D006985:Hyperventilation / Q000503:physiopathology; D000860:Hypoxia / Q000503:physiopathology; D008176:Lung Volume Measurements; D008297:Male; D010609:Pharyngeal Muscles / Q000502:physiology*; D011030:Pneumothorax / Q000503:physiopathology; D015656:Respiratory Mechanics / Q000502:physiology*