title: Elephantiasis nostras of the lips: a case report.
abstract: Elephantiasis nostras (EN) is a clinical entity that usually presents as a persistent swelling of the lower extremities. It has been related to recurrent lymphangitis of bacterial origin that causes a fibrosis and thickening of both epidermal and connective tissue. Although very rare, EN has been previously reported in the lips. This is the first case reported in the oral medicine literature that describes EN involving the lips. We describe the clinical features and a differential diagnosis of the lip lesions and a treatment protocol to which this patient has responded. A diagnosis of EN should be entertained in patients with chronically edematous, scaling lip lesions.
authors.affiliation: University of Pennsylvania School of Dental Medicine, Philadelphia, USA.
authors.forename: T P
authors.initials: TP
authors.lastname: Sollecito
authors.forename: S
authors.initials: S
authors.lastname: DeRossi
authors.forename: J C
authors.initials: JC
authors.lastname: Stewart
authors.forename: D
authors.initials: D
authors.lastname: Ettlin
authors.forename: C
authors.initials: C
authors.lastname: Mowad
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000982:Antipruritics / Q000627:therapeutic use; D001424:Bacterial Infections; D002981:Clindamycin / Q000627:therapeutic use; D003238:Connective Tissue / Q000473:pathology; D003937:Diagnosis, Differential; D004009:Dicloxacillin / Q000008:administration & dosage / Q000627:therapeutic use; D004316:Doxepin / Q000627:therapeutic use; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D004487:Edema / Q000473:pathology; D004604:Elephantiasis / Q000188:drug therapy / Q000473:pathology*; D004817:Epidermis / Q000473:pathology; D004890:Erythema / Q000473:pathology; D004917:Erythromycin / Q000627:therapeutic use; D005260:Female; D005355:Fibrosis; D005500:Follow-Up Studies; D006801:Humans; D008047:Lip Diseases / Q000188:drug therapy / Q000473:pathology*; D008205:Lymphangitis / Q000382:microbiology; D010406:Penicillins / Q000627:therapeutic use; D012008:Recurrence
chemical_list: D000900:Anti-Bacterial Agents; D000982:Antipruritics; D010406:Penicillins; D004316:Doxepin; D002981:Clindamycin; D004917:Erythromycin; D004009:Dicloxacillin