[Genetic polymorphism of antithrombin III in five Chinese populations].
The genetic polymorphisms of antithrombin III (AT III) in 5 Chinese populations were studied by isoelectric focusing on polyacrylamide gels followed by immunoblotting. The products of two alleles at the antithrombin III locus together with 1 AT III anodic variant and 3 cathode variants were observed. The results revealed that the predominant allele of AT III blood group system in Chinese populations was AT III *1, with frequencies between 0.9773-0.9850. Frequencies of AT III *2 ranged from 0.0091 to 0.0169. These results indicate that the polymorphic information content of AT III blood group system in Chinese populations is limited.
Gou
Q
Q
Department of Forensic Biology, Chengdu.
Wu
J
J
Hou
Y
Y
Xu
Y
Y
Jin
Z
Z
Wu
M
M
D000483:Alleles; D000990:Antithrombin III / Q000235:genetics*; D044466:Asian People; D002681:China; D006801:Humans; D010375:Pedigree; D011110:Polymorphism, Genetic
D000990:Antithrombin III