Co-occurrence of AIDS and tuberculosis: results of a database "match" and investigation.
OBJECTIVE
To conduct a match between the AIDS and Tuberculosis (TB) Registries in Philadelphia.


METHODS
Database extracts for the year 1993 were prepared manually and matched by name, birth date, and social security number. Reported cases not matching with those on the primary registry were investigated. Proportion levels of comorbidity were calculated. Predictors of comorbidity were evaluated separately for the TB sample and for the AIDS sample.


RESULTS
The proportion of comorbid patients with AIDS alive at midyear was 4.7%; 17.1% of TB cases were also HIV-positive. Twenty-three percent of AIDS cases were falsely reported as having active TB; the false-positive rate in TB Control for HIV seropositivity was 4.2%. Having public or no health insurance, injection drug use (IDU) or heterosexual risk background (HET), and being nonwhite and female were significant predictors of active TB in persons with AIDS.


CONCLUSIONS
A registries' data match can provide useful information and result in improved validity for both registries. Although women with AIDS initially appeared to have a higher risk of having active TB, additional parallel analyses suggested that this effect was primarily the result of the 1993 expansion of the definition of AIDS.
Gollub
E L
EL
AIDS Activities Coordinating Office and the TB Control Division, Department of Public Health, Philadelphia, Pennsylvania 19146, U.S.A.
Trino
R
R
Salmon
M
M
Moore
L
L
Dean
J L
JL
Davidson
B L
BL
D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology*; D015897:Comorbidity / Q000639:trends; D016208:Databases, Factual / Q000706:statistics & numerical data*; D005189:False Positive Reactions; D005260:Female; D006679:HIV Seropositivity / Q000453:epidemiology; D006801:Humans; D008297:Male; D015143:Philadelphia / Q000453:epidemiology; D011237:Predictive Value of Tests; D011634:Public Health / Q000706:statistics & numerical data; D012042:Registries / Q000706:statistics & numerical data*; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000453:epidemiology*