title: Cytokine signaling: cytokine-inducible signaling inhibitors.
abstract: Seven members of a family of cytokine-inducible proteins have been identified, a number of which have been shown to act as negative regulators of cytokine action. All of these proteins contain a central Src homology 2 domain, as well as conserved motifs in their carboxy-terminal regions.
authors.affiliation: Laboratory of Molecular Immunology, National Institute of Health, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20893, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Aman
authors.forename: W J
authors.initials: WJ
authors.lastname: Leonard
mesh_terms: D000595:Amino Acid Sequence; D001665:Binding Sites; D016207:Cytokines / Q000378:metabolism*; D006801:Humans; D017874:Immediate-Early Proteins / Q000737:chemistry / Q000378:metabolism* / Q000502:physiology; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid; D015398:Signal Transduction; D050826:Suppressor of Cytokine Signaling Proteins; D018909:src Homology Domains
chemical_list: D016207:Cytokines; D017874:Immediate-Early Proteins; D050826:Suppressor of Cytokine Signaling Proteins