[A case of successful treatment with ganciclovir for cytomegalovirus pneumonia after pulmonary lobectomy].
The premortem diagnosis of cytomegalovirus (CMV) pneumonia is usually difficult, and mortality of it is high. A case of successful treatment with ganciclovir for cytomegalovirus pneumonia after pulmonary lobectomy is reported. The patient was a 76-year-old man. Under diagnosis as lung cancer, the right lower lobectomy was performed. After operation, pneumonia occurred on the nonoperated side and in a few days reticular shadows rapidly spread to the whole lung. Although pulse steroid therapy was performed, the interstitial pneumonitis improved only a little. Then intranuclear inclusion body-bearing giant cells were found in sputum obtained by bronchoscopy. So we diagnosed the interstitial pneumonitis as CMV pneumonia and ganciclovir was administrated. CMV pneumonia had improved for two weeks and the patient has no recurrence. When interstitial pneumonitis develop in patients after operation or steroid therapy, the differential diagnosis should include the possibility of CMV pneumonia.
Inaba
H
H
Department of Respiratory Surgery, Shizuoka General Hospital, Japan.
Ohta
S
S
Nishimura
T
T
Takamochi
K
K
Ishida
I
I
Etoh
T
T
Honda
A
A
Nakajima
H
H
Muro
H
H
Nagashima
Y
Y
D000368:Aged; D000998:Antiviral Agents / Q000627:therapeutic use*; D003586:Cytomegalovirus Infections / Q000188:drug therapy*; D015774:Ganciclovir / Q000627:therapeutic use*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000188:drug therapy*; D008297:Male; D011013:Pneumonectomy; D011024:Pneumonia, Viral / Q000188:drug therapy*; D011183:Postoperative Complications / Q000188:drug therapy
D000998:Antiviral Agents; D015774:Ganciclovir