[The optimum time interval for applying lidocaine containing adhesive tape is 6 to 8 hours for venipuncture pain relief].
Lidocaine containing adhesive tape (LT) is a pressure sensitive adhesive tape which contains 60% of lidocaine in base form. We investigated the optimum time interval for applying LT for venipuncture pain relief by using visual analogue scale (VAS). Six hundred seventeen cases were prospectively divided into 0.5, 1, 2, 3, 4, 6, 8, 12 hour groups. LT was applied on the dorsum of the hand and the vein was punctured with a 20 gauge polyurethane catheter (Insyte TM: Becton Dickinson, USA). The level of pin prick sensation was reduced in accordance with the duration of LT application. While the median of the pin prick sensation level was below 5% of control in the longer than 6 hour groups, the 90 percentile was 30% and 60% in 6 hour and 12 hour group, respectively. This suggested a possible poor skin contact of LT in the 12 hour group. VAS of venipuncture pain was significantly improved as the duration of LT application increased. When the punctures was smooth the median values of VAS in 6 and 8 hour groups were both less than 5%. Even with rough venipuncture, significant pain relief was observed in longer than 3 hour groups. We concluded that 6 to 8 hour applying of LT was optimum for pain relief of venipuncture.
Nakao
M
M
Department of Anesthesiology and Pain Control, Chuden Hospital, Chugoku Electric Power Company Incorporated, Hiroshima.
Onji
I
I
D000287:Administration, Topical; D000293:Adolescent; D000328:Adult; D000368:Aged; D000779:Anesthetics, Local / Q000008:administration & dosage* / Q000009:adverse effects; D004304:Dosage Forms; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage* / Q000009:adverse effects; D008875:Middle Aged; D010146:Pain / Q000209:etiology / Q000517:prevention & control*; D018962:Phlebotomy / Q000009:adverse effects*; D011446:Prospective Studies; D013997:Time Factors
D000779:Anesthetics, Local; D004304:Dosage Forms; D008012:Lidocaine