[Clinical significance of c-erbB2 oncoprotein expression in stomach carcinoma].
This paper reports a study of the c-erbB2 oncoprotein (by immunohistochemical method) in 97 gastric carcinoma resected at Shanghai Cancer Hospital in 1991. In 30 out of the 97 cases (30.9%) c-erbB2 was positive and its expression was higher among patients with lymph node metastasis (P < 0.05). Univariate and multivariate analyses indicated that c-erbB2 expression betokened poor prognosis.
Gong
Z
Z
Department of Surgery, Huadong Hospital, Shanghai.
Luo
E
E
Lu
Q
Q
D000230:Adenocarcinoma / Q000378:metabolism* / Q000556:secondary; D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D015870:Gene Expression; D006801:Humans; D007150:Immunohistochemistry; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000096:biosynthesis*; D013274:Stomach Neoplasms / Q000378:metabolism* / Q000473:pathology
D018719:Erb-b2 Receptor Tyrosine Kinases