Are more complex implantable cardioverter defibrillators associated with an increased mortality? Lessons learned from clinical trials.
We compared 1-year survival in patients receiving implantable cardioverter defibrillators (ICDs) that provide only shock therapy with more advanced ICDs that provide antitachycardia pacing, bradycardia pacing, low-energy cardioversion, and advanced detection algorithms. Outcome in patients with advanced-generation ICD systems was similar or improved compared with outcome in patients receiving ICDs with only monophasic shock.
Ellenbogen
K A
KA
Department of Medicine, Medical College of Virginia and the McGuire VA Medical Center, Richmond 23298-0053, USA.
Epstein
A E
AE
Wood
M A
MA
Stambler
B S
BS
Kay
G N
GN
Plumb
V J
VJ
Voshage-Stahl
L
L
Hull
M L
ML
D002986:Clinical Trials as Topic; D016757:Death, Sudden, Cardiac / Q000209:etiology*; D017147:Defibrillators, Implantable / Q000009:adverse effects*; D004867:Equipment Design; D004868:Equipment Failure; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016019:Survival Analysis; D013610:Tachycardia / Q000150:complications / Q000401:mortality* / Q000628:therapy