title: New insights from spectroscopy into the structure/function relationships of lipoxygenases.
abstract: Spectroscopic properties of the redox-active iron in the active site of plant and mammalian lipoxygenases can now be combined with recent crystal structure determinations to obtain new insights into lipoxygenase reaction mechanisms.
authors.affiliation: Department of Chemistry, Stanford University, Standford, CA 94805, USA. solomon@chem.stanford.edu
authors.forename: E I
authors.initials: EI
authors.lastname: Solomon
authors.forename: J
authors.initials: J
authors.lastname: Zhou
authors.forename: F
authors.initials: F
authors.lastname: Neese
authors.forename: E G
authors.initials: EG
authors.lastname: Pavel
mesh_terms: D018360:Crystallography, X-Ray; D007501:Iron / Q000378:metabolism; D007527:Isoenzymes / Q000737:chemistry / Q000378:metabolism*; D008084:Lipoxygenase / Q000737:chemistry / Q000378:metabolism*; D008958:Models, Molecular; D010084:Oxidation-Reduction; D011487:Protein Conformation; D013025:Glycine max / Q000201:enzymology; D013053:Spectrophotometry; D013329:Structure-Activity Relationship
chemical_list: D007527:Isoenzymes; D007501:Iron; D008084:Lipoxygenase