title: Blood group gene frequency in a selected north Indian population.
abstract: Gene frequencies have been calculated from 6334 blood donors who were tested at a referral hospital in north India, for ABO & Rh and from > 350 donors who were tested for other blood groups. The Hardy Weinberg equation for 2 allel systems and the Bernstein method for 3 or more allel systems have been employed for calculating gene frequencies. The predominance of blood group B (37.39%), Rh D negative frequency of 4.63 per cent, predominance of M gene (0.6383) and M s haplotype (0.4464) and S gene frequency below 0.3 (0.2069) agrees with earlier data. The new findings include the presence of the allels Fy (a-b-) (0.44%) in the Duffy group, S- s- (1.16%) in the Ss group and JK (a-b-) (0.54%) in the Kidd blood group system. These have not been reported in the Indian population.
authors.affiliation: Department of Transfusion Medicine, All India Institute of Medical Sciences, New Delhi.
authors.forename: A
authors.initials: A
authors.lastname: Nanu
authors.forename: R M
authors.initials: RM
authors.lastname: Thapliyal
mesh_terms: D001789:Blood Group Antigens / Q000235:genetics*; D005787:Gene Frequency; D006801:Humans; D007194:India
chemical_list: D001789:Blood Group Antigens