title: Clinical observation on efficacy of electro-acupuncture therapy in hyperplasia of mammary glands and its effect on immunological function.
abstract: Based on our work on electro-acupuncture therapy of hyperplasia of mammary glands and in order to observe further the relationship between immunological function and E2 in hyperplasia of mammary glands, we determined the change not only in immunological function before and after electro-acupuncture in 44 in-patients with hyperplasia of mammary glands and having the same menstruation date, but also in electro-acupuncture treated rat hyperplasia of mammary glands model. We found that there was decrease of immunological function in hyperplasia of mammary glands and this function could be remarkably enhanced by electro-acupuncture both in hyperplasia of mammary glands patients and in rat hyperplasia of mammary glands model. The mechanism implies it might be that the inhibitory effect on immunological function exerted by high concentration of E2 was lowered by electro-acupuncture, hence the immunological function was reinforced. The results of this study are important in exploration of both the pathogenesis of this disease and the mechanism of electro-acupuncture, and in reducing the incidence of breast carcinoma.
authors.affiliation: Shaanxi College of Traditional Chinese Medicine, Xianyang.
authors.forename: C
authors.initials: C
authors.lastname: Guo
authors.forename: W
authors.initials: W
authors.lastname: Zhang
authors.forename: S
authors.initials: S
authors.lastname: Zheng
authors.forename: D
authors.initials: D
authors.lastname: Ju
authors.forename: C
authors.initials: C
authors.lastname: Zhao
mesh_terms: D000328:Adult; D000818:Animals; D015671:Electroacupuncture; D004958:Estradiol / Q000097:blood; D005260:Female; D005348:Fibrocystic Breast Disease / Q000276:immunology / Q000628:therapy*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D008213:Lymphocyte Activation; D008597:Menstrual Cycle; D008875:Middle Aged; D051381:Rats; D017207:Rats, Sprague-Dawley; D012397:Rosette Formation
chemical_list: D007074:Immunoglobulin G; D004958:Estradiol