[Involvement of medullary tail-flick related neurons in the descending facilitating effects evoked by stimulation of lateral habenular nucleus].
In lightly anesthetized rats 3 classes of neurons in the rostral ventromedial medulla (RVM) were in relation to tail-flick reflex (TF) recorded, i. e. the TF triggired on-cells, the TF triggered off-cells and the non-responsive or neutral cells. When lateral habenular nucleus (LHb) was stimulated the on-cells were excited, the off-cells inhibited while the neutral cells unaffected. The fact that stimulation of LHb facilitated tail-flick reflex appears to be quite well explained by its enhancement effect on the tail-flick related response of both the on- and the off-cells. These results indicate that the facilitating action of LHb on spinal defensive reflex is probably brought out by participation of the medullary tail-flick related cell activity.
Huang
L X
LX
Department of Physiology, Xi'an Medical University.
Cheng
Z F
ZF
D000818:Animals; D004558:Electric Stimulation; D004594:Electrophysiology; D005260:Female; D008297:Male; D008526:Medulla Oblongata / Q000166:cytology / Q000502:physiology*; D009474:Neurons / Q000502:physiology; D009619:Nociceptors / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012018:Reflex / Q000502:physiology; D013116:Spinal Cord / Q000502:physiology*; D013787:Thalamic Nuclei / Q000502:physiology*