title: [Self-contained cryoapplicators made of porous titanium nickelide in the treatment of precancer of the lip and oral mucosa].
abstract: A set of autonomic cryoapplicators of porous titanium nickelide is designed, their physical parameters described, and cryogenic properties studied on gelatin model. Ninety-eight patients with precancer diseases of the red lips and buccal mucosa were treated using these applicators. The applicators are easy to use and meet the requirements to cryoinstruments. Cryoexposure is to be performed during the first minute after coolant charging, when the temperature of the applicators is close to the nitrogen one. The larger is the diameter of the working piece of the applicator and the larger is the device, the more ice is formed. The depth of freezing is 2 to 6 mm. The choice of an applicator, duration of cryoexposure, number of cryocontacts, and cycles of freezing and thawing depend on the form of precancer disease, size of lesions, and degree of the pathological changes. Good results were attained in 96.9 +/- 1.6% of patients.
authors.forename: M D
authors.initials: MD
authors.lastname: Filirin
authors.forename: P G
authors.initials: PG
authors.lastname: Sysoliatin
authors.forename: V E
authors.initials: VE
authors.lastname: Giunter
authors.forename: A A
authors.initials: AA
authors.lastname: Sogomonian
mesh_terms: D000497:Alloys; D003452:Cryosurgery / Q000295:instrumentation* / Q000706:statistics & numerical data; D004867:Equipment Design; D005500:Follow-Up Studies; D006801:Humans; D008048:Lip Neoplasms / Q000601:surgery*; D009061:Mouth Mucosa / Q000601:surgery; D009062:Mouth Neoplasms / Q000601:surgery*; D009532:Nickel; D016062:Porosity; D011230:Precancerous Conditions / Q000601:surgery*; D014025:Titanium
chemical_list: D000497:Alloys; C040654:titanium nickelide; D009532:Nickel; D014025:Titanium