Opioid receptors: pinning down the opiate targets.
Recent studies of knockout mice conclusively show that the mu opioid receptor mediates the analgesic effects of morphine; they further suggest that the mu opioid receptor also has a role in mediating the effects of other opioid agonists, and provide insights into the non-analgesic effects of mu opioids.
Childers
S R
SR
Department of Physiology/Pharmacology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, North Carolina 27157, USA.
D000818:Animals; D051379:Mice; D018345:Mice, Knockout; D009020:Morphine / Q000494:pharmacology*; D011957:Receptors, Opioid / Q000172:deficiency / Q000187:drug effects / Q000235:genetics / Q000502:physiology
D011957:Receptors, Opioid; D009020:Morphine