Clinical and biologic features of the AIDS dementia complex.
Human immunodeficiency virus type 1 infection is frequently associated with complications of the nervous system, involving all levels of the neuraxis. Many of these represent focal disorders, such as toxoplasmosis, lymphoma, and progressive multifocal leukoencephalopathy. This article reviews the salient clinical and biological features of these disorders.
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Department of Neurology, Tufts University School of Medicine, Boston, Massachusetts, USA.
D015526:AIDS Dementia Complex / Q000134:cerebrospinal fluid / Q000188:drug therapy / Q000473:pathology / Q000503:physiopathology*; D017088:AIDS-Related Opportunistic Infections / Q000473:pathology / Q000503:physiopathology; D019380:Anti-HIV Agents / Q000627:therapeutic use; D001519:Behavior / Q000502:physiology; D001695:Biology; D001932:Brain Neoplasms / Q000473:pathology / Q000503:physiopathology; D003071:Cognition / Q000502:physiology; D015497:HIV-1; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000473:pathology / Q000503:physiopathology; D016483:Lymphoma, AIDS-Related / Q000473:pathology / Q000503:physiopathology; D011597:Psychomotor Performance / Q000502:physiology; D016781:Toxoplasmosis, Cerebral / Q000473:pathology / Q000503:physiopathology; D015215:Zidovudine / Q000627:therapeutic use
D019380:Anti-HIV Agents; D015215:Zidovudine