[Assessing the efficacy of DNA hybridization for diagnosis of adenoviral and chlamydial diseases of eyes].
Analysis of scrapings off the conjunctiva of patients with suspected adenoviral infection (n = 60) and ophthalmochlamydiasis (n = 132) by different diagnostic tests showed good prospects of using DNA hybridization: the efficacy of detecting adenoviral diseases of the eyes was 35% improved in comparison with the fluorescent antibody method with polyclonal serum and the diagnosis of ophthalmochlamydiasis was 22.8% improved in comparison with enzyme immunoassay.
Skopinskaia
S N
SN
NII of Eyes Diseases, Moscow.
Andzhelov
V O
VO
Vakhova
E S
ES
D000257:Adenoviridae Infections / Q000175:diagnosis* / Q000821:virology; D000260:Adenoviruses, Human / Q000235:genetics*; D000293:Adolescent; D000328:Adult; D002692:Chlamydia trachomatis / Q000235:genetics*; D003235:Conjunctivitis, Inclusion / Q000175:diagnosis* / Q000382:microbiology; D003236:Conjunctivitis, Viral / Q000175:diagnosis* / Q000821:virology; D004269:DNA, Bacterial / Q000032:analysis*; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D007124:Immunoenzyme Techniques; D017403:In Situ Hybridization / Q000379:methods; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity
D004269:DNA, Bacterial; D004279:DNA, Viral