The P-glycoprotein multidrug transporter: interactions with membrane lipids, and their modulation of activity.
Sharom
F J
FJ
Guelph-Waterloo Centre for Graduate Work in Chemistry, Department of Chemistry and Biochemistry, University of Guelph, Ontario, Canada.
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism*; D000251:Adenosine Triphosphatases / Q000378:metabolism; D000818:Animals; D002462:Cell Membrane / Q000378:metabolism* / Q000648:ultrastructure; D004134:Dimyristoylphosphatidylcholine; D018432:Drug Resistance, Multiple; D008051:Lipid Bilayers; D008563:Membrane Lipids / Q000378:metabolism*; D008954:Models, Biological; D008958:Models, Molecular; D010743:Phospholipids / Q000494:pharmacology; D011487:Protein Conformation
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D008051:Lipid Bilayers; D008563:Membrane Lipids; D010743:Phospholipids; D000251:Adenosine Triphosphatases; D004134:Dimyristoylphosphatidylcholine