Acceptability of genital herpes immunization. The role of health beliefs and health behaviors.
OBJECTIVE
Little is known about the acceptability of vaccines for prevention of sexually transmitted diseases (STDs). The purpose of this study was to examine potential predictors of genital herpes simplex virus type 2 (HSV-2) vaccine acceptability.


OBJECTIVE
To evaluate the relationship of health beliefs and health behaviors to HSV-2 vaccine acceptability.


METHODS
Three hundred twenty-one subjects participating in two phase III clinical trials for an HSV-2 vaccine completed surveys addressing health beliefs, health behaviors, and acceptability of hypothetical HSV-2 vaccines.


RESULTS
Bivariate analyses found that perceived benefits of vaccination, seatbelt use, a healthy diet, and having had cholesterol levels checked were associated with higher acceptability. Perceived limitations of HSV-2 immunization, alcohol use, and exercise were associated with lower acceptability. Multiple regression analysis identified perceived benefits of vaccination, decreased exercise, and lower alcohol use as significant independent predictors of greater HSV-2 vaccine acceptability.


CONCLUSIONS
In groups of high-risk individuals who had completed participation in HSV-2 clinical trials, health beliefs and health behaviors influenced acceptability of hypothetical HSV-2 vaccination. The findings support the need to understand determinants of acceptance of vaccines for HSV-2 and other STDs.
Zimet
G D
GD
Section of Adolescent Medicine, Indiana University School of Medicine, Indianapolis, USA.
Fortenberry
J D
JD
Fife
K H
KH
Tyring
S K
SK
Herne
K
K
Douglas
J M
JM
D000328:Adult; D000368:Aged; D005260:Female; D015438:Health Behavior; D006558:Herpes Genitalis / Q000517:prevention & control*; D018258:Herpesvirus 2, Human / Q000276:immunology*; D006801:Humans; D007114:Immunization; D008297:Male; D008875:Middle Aged; D010342:Patient Acceptance of Health Care; D012044:Regression Analysis; D014765:Viral Vaccines / Q000276:immunology*
D014765:Viral Vaccines