title: Organochlorine pesticides, polychlorinated biphenyls, polychlorinated dibenzo-p-dioxins and dibenzofurans in human adipose tissue from western Kyungnam, Korea.
abstract: Hexachlorocyclohexanes (HCHs), dichlorodiphenyl trichloroethane and its metabolites (DDTs), hexachlorobenzene (HCB), polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDDs/DFs) were determined in human adipose tissue samples collected from western Kyungnam, Korea. The residue levels of organochlorine compounds were in the order of DDTs followed by PCBs > HCHs > HCB > PCDDs/DFs. The mean concentrations of 2,3,7,8-TeCDD in male and female tissues were 2.8 and 1.7 pg.g-1 on lipid weight basis, respectively. No significant difference was found in the residue levels of PCDDs/DFs between sexes. In contrast, PCBs and DDTs showed a significant difference between sexes. Unlike the age trend observed for HCHs, PCBs and DDTs, PCDDs/DFs revealed a constant or rather decreasing pattern with increasing age. This is the first report on PCDDs/DFs contamination in human adipose tissue from Korea. Organochlorine concentrations in human adipose tissues from western Kyungnam were generally much lower than those of other countries.
authors.affiliation: Department of Environment Conservation, Ehime University, Japan.
authors.forename: Y S
authors.initials: YS
authors.lastname: Kang
authors.forename: M
authors.initials: M
authors.lastname: Matsuda
authors.forename: M
authors.initials: M
authors.lastname: Kawano
authors.forename: T
authors.initials: T
authors.lastname: Wakimoto
authors.forename: B Y
authors.initials: BY
authors.lastname: Min
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism*; D000328:Adult; D000368:Aged; D001572:Benzofurans / Q000378:metabolism*; D002849:Chromatography, Gas; D000072338:Dibenzofurans, Polychlorinated; D005260:Female; D006801:Humans; D007306:Insecticides / Q000378:metabolism*; D007723:Korea; D008297:Male; D008875:Middle Aged; D010573:Pesticide Residues / Q000378:metabolism; D011078:Polychlorinated Biphenyls / Q000378:metabolism*; D000072317:Polychlorinated Dibenzodioxins / Q000031:analogs & derivatives* / Q000378:metabolism; D012737:Sex Factors; D012989:Soil Pollutants / Q000378:metabolism*
chemical_list: D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D007306:Insecticides; D010573:Pesticide Residues; D000072317:Polychlorinated Dibenzodioxins; D012989:Soil Pollutants; D011078:Polychlorinated Biphenyls