T-cell regulation: Thy-1 - hiding in full view.
Thy-1 is a highly abundant glycoprotein on the surface of thymocytes and neurons. A null mutation in the gene encoding Thy-1 deregulates T-cell receptor signaling and causes abnormal thymocyte development; does this mean that Thy-1 has a signaling function?
Killeen
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Department of Microbiology and Immunology, University of California, San Francisco, California 94143-0414, USA.
D000818:Animals; D002454:Cell Differentiation; D051379:Mice; D018345:Mice, Knockout; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000166:cytology / Q000378:metabolism*; D018800:Thy-1 Antigens / Q000235:genetics / Q000378:metabolism*
D018800:Thy-1 Antigens