title: Continued development of the Nimbus/University of Pittsburgh (UOP) axial flow left ventricular assist system.
abstract: Nimbus and the University of Pittsburgh (UOP) have continued the development of a totally implanted axial flow blood pump under the National Institutes of Health (NIH) Innovative Ventricular Assist System (IVAS) program. This 62 cc device has an overall length of 84 mm and an outer diameter of 34.5 mm. The inner diameter of the blood pump is 12 mm. It is being designed to be a totally implanted permanent device. A key achievement during the past year was the completion of the Model 2 pump design. Ten of these pumps have been fabricated and are being used to conduct in vitro and in vivo experiments to evaluate the performance of different materials and hydraulic components. Efforts for optimizing the closed loop speed control have continued using mathematical modeling, computer simulations, and in vitro and in vivo testing. New hydraulic blade designs have been tested using computational fluid dynamics (CFD) and flow visualization. A second generation motor was designed with improved efficiency. To support the new motor, a new motor controller fabricated as a surface mount PC board has been completed. The program is now operating under a formal QA system.
authors.affiliation: Nimbus Inc., Rancho Cordova, California 95670, USA.
authors.forename: D C
authors.initials: DC
authors.lastname: Thomas
authors.forename: K C
authors.initials: KC
authors.lastname: Butler
authors.forename: L P
authors.initials: LP
authors.lastname: Taylor
authors.forename: P
authors.initials: P
authors.lastname: Le Blanc
authors.forename: B P
authors.initials: BP
authors.lastname: Griffith
authors.forename: R L
authors.initials: RL
authors.lastname: Kormos
authors.forename: H S
authors.initials: HS
authors.lastname: Borovetz
authors.forename: P
authors.initials: P
authors.lastname: Litwak
authors.forename: M V
authors.initials: MV
authors.lastname: Kameneva
authors.forename: S
authors.initials: S
authors.lastname: Choi
authors.forename: G W
authors.initials: GW
authors.lastname: Burgreen
authors.forename: W R
authors.initials: WR
authors.lastname: Wagner
authors.forename: Z
authors.initials: Z
authors.lastname: Wu
authors.forename: J F
authors.initials: JF
authors.lastname: Antaki
mesh_terms: D000818:Animals; D001696:Biomechanical Phenomena; D001698:Biomedical Engineering; D005069:Evaluation Studies as Topic; D006353:Heart-Assist Devices; D006801:Humans; D066298:In Vitro Techniques; D011474:Prosthesis Design