[Effects of hormone replacement treatment of menopause on the risk of venous thromboembolic disease].
Post-menopausal hormone replacement therapy increases the risk of venous thrombo-embolism 2- to 4-fold. The risk is highest in the beginning of the exposure to hormones and disappears rapidly after interruption of treatment. However, the increased risk remains low in absolute value and has to be weighed against coronary artery disease and post-menopausal osteoporosis.
Thery
C
C
Service de Soins Intensifs, Hôpital Cardiologique, Lille, France.
Prat
A
A
Asseman
P
P
Bauchart
J J
JJ
Michon
P
P
Lesenne
M
M
Jude
B
B
D015914:Estrogen Replacement Therapy / Q000009:adverse effects*; D005260:Female; D006487:Hemostasis; D006801:Humans; D008593:Menopause / Q000187:drug effects*; D008875:Middle Aged; D012307:Risk Factors; D013923:Thromboembolism / Q000139:chemically induced*