Isolation and mapping of two chicken POU family genes and the identification of a syntenic group with human and mouse.
Two partial chicken POU domain genes were isolated by genomic library screening and reverse transcriptase-polymerase chain reaction (RT-PCR). A cDNA clone encoding the POU domain of Brn-3a, which showed near identity to the human Brn-3a sequence (100% amino acid identity), was isolated and mapped to chicken linkage group E48. A Skn-1/Epoc-1/Oct-11 genomic clone was identified and mapped to chicken linkage group E49. This mapping identified a syntenic group in chicken linkage group E49 that was conserved with human chromosome 11q23 and mouse chromosome 9.
Heltemes
L M
LM
Program of Immunobiology, Iowa State University, Ames 50011, USA.
Tuggle
C K
CK
Lamont
S J
SJ
D000595:Amino Acid Sequence; D000818:Animals; D029742:Caenorhabditis elegans Proteins; D002645:Chickens / Q000235:genetics*; D002874:Chromosome Mapping; D002880:Chromosomes, Human, Pair 11; D017124:Conserved Sequence; D004268:DNA-Binding Proteins / Q000235:genetics; D008040:Genetic Linkage; D015801:Helminth Proteins / Q000235:genetics; D006801:Humans; D051379:Mice; D005810:Multigene Family; D050810:Octamer Transcription Factors; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D050818:Transcription Factor Brn-3; D014157:Transcription Factors / Q000235:genetics*
D029742:Caenorhabditis elegans Proteins; D004268:DNA-Binding Proteins; D015801:Helminth Proteins; D050810:Octamer Transcription Factors; C484169:POU2F3 protein, human; C084342:Pou2f3 protein, mouse; D050818:Transcription Factor Brn-3; D014157:Transcription Factors; C073702:skn-1 protein, C elegans