title: [Hemodynamic effects of continuous epidural infusion with local anesthetics].
abstract: Epidural blockade with local anesthetic may cause hypotension resulting from sympathetic block and/or systemic effect produced by absorbed local anesthetic through epidural blood vessels. In the present study, we compared the hemodynamic effects of saline 0.5 ml.h-1, lidocaine 0.5 ml.h-1, bupivacaine 0.5 ml.h-1, lidocaine 2 ml.h-1, and bupivacaine 2 ml.h-1, which were given epidurally combined with morphine. There was not significant difference in hemodynamics among 5 groups. Continuous epidural infusion with a small dose of local anesthetic agent combined with morphine is unlikely to induce apparent hemodynamic effects during postoperative period.
authors.affiliation: Department of Anesthesiology and Critical Care Medicine, Gifu University School of Medicine.
authors.forename: A
authors.initials: A
authors.lastname: Oda
authors.forename: H
authors.initials: H
authors.lastname: Iida
authors.forename: S
authors.initials: S
authors.lastname: Dohi
mesh_terms: D000328:Adult; D000368:Aged; D015360:Analgesia, Epidural; D000779:Anesthetics, Local / Q000494:pharmacology*; D002045:Bupivacaine / Q000494:pharmacology*; D004824:Epidural Space; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007260:Infusion Pumps; D008012:Lidocaine / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine; D002045:Bupivacaine