T-cell subsets: transcriptional control in the Th1/Th2 decision.
Transcriptional mechanisms in CD4(+) T cells and antigen-presenting cells determine the activation or differentiation of Th1 and Th2 helper cell subsets, and also form attractive targets for therapeutic intervention in the balance of Th1/Th2 responses.
Rincón
M
M
Section of Immunobiology, Yale University School of Medicine, New Haven, Connecticut, 06520, USA.
Flavell
R A
RA
D000818:Animals; D018417:Th1 Cells / Q000378:metabolism*; D018418:Th2 Cells / Q000378:metabolism*; D014158:Transcription, Genetic