[Accident during retinal fluorescein angiography].
OBJECTIVE
To evaluate adverse reactions frequency following fluorescein i.v. administration to perform retinoic angiography (ARF).


METHODS
Retrospective study.


METHODS
Eye Clinic of the University of Florence.


METHODS
6524 patients undergoing 10,003 ARF. PARAMETERS EVALUATED: For each patient age, sex, concomitant diseases, previous ARF, allergic history and any adverse reaction were evaluated.


RESULTS
Adverse experiences were described in 7.5% of 6524 patients. Most of the observed reactions were mild: nausea (3.8%), vomiting (0.43%), vasovagal phenomena (1.18%), anaphylactoid reactions (1.84%). A major rate of adverse reactions were observed in patients previously submitted to ARF who reported in the anamnesis a previous adverse reaction, and in those with a positive allergic history. Severe reactions occurred in 0.27% of patients, but only in 2 of 6524 patients a rianimatory treatment (0.03) was necessary.


CONCLUSIONS
From the data retrospective analysis it was observed that the manifestation of mild adverse effects was to be expected in many cases. It was therefore possible to point out classes of patients at risk (patients who reported a previous adverse reaction after ARF and patients with positive allergic history). Unfortunately it was not possible to expect and so to prevent the severe effects. Thus it is recommended to perform ARF in an adequately equipped room.
Lepri
A
A
Istituto di Anestesia e Rianimazione, Università degli Studi, Firenze.
Salvini
R
R
Rizzo
L
L
Cetica
P
P
Grechi
S
S
Di Filippo
A
A
Conti
M
M
Benvenuti
S
S
Novelli
G P
GP
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D005451:Fluorescein Angiography / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies