Nebulized morphine in the palliation of dyspnoea.
Seventeen terminally ill cancer patients with primary or secondary intrathoracic malignancy complaining of breathlessness were treated with nebulized morphine in doses of 20 mg 4-hourly for 48 h. The effect on dyspnoea was evaluated using the Dyspnoea Assessment Questionnaire. Most patients felt less dyspnoeic after 24 h; the effect was maintained, but not improved upon, after 48 h.
Zeppetella
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St Joseph's Hospice, Hackney, London, UK.
D000280:Administration, Inhalation; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D004334:Drug Administration Schedule; D004417:Dyspnea / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage*; D010166:Palliative Care / Q000379:methods*; D011446:Prospective Studies; D012720:Severity of Illness Index
D000701:Analgesics, Opioid; D009020:Morphine