Discovery and development of non-peptide antagonists of peptide hormone receptors.
Pettibone
D J
DJ
Department of Pharmacology, Merck Research Laboratories, West Point, PA 19486, USA.
Freidinger
R M
RM
D000818:Animals; D065092:Antidiuretic Hormone Receptor Antagonists; D002164:Camphor / Q000031:analogs & derivatives / Q000494:pharmacology; D005260:Female; D019204:GTP-Binding Proteins / Q000502:physiology; D006727:Hormone Antagonists / Q000494:pharmacology*; D006801:Humans; D007752:Obstetric Labor, Premature / Q000517:prevention & control; D010121:Oxytocin / Q000037:antagonists & inhibitors*; D011247:Pregnancy; D011956:Receptors, Cell Surface / Q000037:antagonists & inhibitors / Q000502:physiology*; D011949:Receptors, Cholecystokinin / Q000037:antagonists & inhibitors / Q000502:physiology; D018045:Receptors, Oxytocin / Q000037:antagonists & inhibitors / Q000502:physiology*; D017483:Receptors, Vasopressin / Q000502:physiology*
D065092:Antidiuretic Hormone Receptor Antagonists; D006727:Hormone Antagonists; D011956:Receptors, Cell Surface; D011949:Receptors, Cholecystokinin; D018045:Receptors, Oxytocin; D017483:Receptors, Vasopressin; D010121:Oxytocin; D002164:Camphor; D019204:GTP-Binding Proteins