title: Early results with partial left ventriculectomy.
abstract: OBJECTIVE
  We sought to determine the role of partial left ventriculectomy in patients with dilated cardiomyopathy.
  
  
  METHODS
  Since May 1996 we have performed partial left ventriculectomy in 53 patients, primarily (94%) in heart transplant candidates. The mean age of the patients was 53 years (range 17 to 72 years); 60% were in class IV and 40% in class III. Preoperatively, 51 patients were thought to have idiopathic dilated cardiomyopathy, one familial cardiomyopathy, and one valvular cardiomyopathy. As our experience accrued we increased the extent of left ventriculectomy and more complex mitral valve repairs. For two patients mitral valve replacement was performed. For 51 patients the anterior and posterior mitral valve leaflets were approximated (Alfieri repair); 47 patients also had ring posterior annuloplasty. In 27 patients (51%) one or both papillary muscles were divided, additional left ventricular wall was resected, and the papillary muscle heads were reimplanted.
  
  
  RESULTS
  Echocardiography showed a significant decrease in left ventricular dimensions after resection (8.3 cm to 5.8 cm), reduction in mitral regurgitation (2.8+ to 0), and increase in forward ejection fraction (15.7% to 32.7%). Cardiac index did not increase significantly (2.2 to 2.4 L/min per square meter). Eight patients (15%) required a perioperative left ventricular assist device; one died and was the only perioperative mortality (1.9%). At 11 months, actuarial survival was 87% and freedom from relisting for transplantation was 72%.
  
  
  CONCLUSIONS
  Improved selection criteria are necessary to avoid early failures, and much more follow-up and analyses of data are mandatory. However, the operation may become a biologic bridge, or even alternative, to transplantation.
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Ohio 44195, USA.
authors.forename: P M
authors.initials: PM
authors.lastname: McCarthy
authors.forename: R C
authors.initials: RC
authors.lastname: Starling
authors.forename: J
authors.initials: J
authors.lastname: Wong
authors.forename: G M
authors.initials: GM
authors.lastname: Scalia
authors.forename: T
authors.initials: T
authors.lastname: Buda
authors.forename: R L
authors.initials: RL
authors.lastname: Vargo
authors.forename: M
authors.initials: M
authors.lastname: Goormastic
authors.forename: J D
authors.initials: JD
authors.lastname: Thomas
authors.forename: N G
authors.initials: NG
authors.lastname: Smedira
authors.forename: J B
authors.initials: JB
authors.lastname: Young
mesh_terms: D002311:Cardiomyopathy, Dilated / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D018618:Echocardiography, Doppler, Color; D017548:Echocardiography, Transesophageal; D005260:Female; D019918:Heart Valve Prosthesis Implantation; D006352:Heart Ventricles / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000601:surgery; D010210:Papillary Muscles / Q000601:surgery; D011446:Prospective Studies; D015996:Survival Rate; D016896:Treatment Outcome