title: [A study of intraarticular irrigation-injection therapy of temporomandibular joint and its mechanism].
abstract: According to the research that there were some immune and inflammatory substances in the synovial fluid of temporomandibular joint disturbance syndrome (TMJDS), we improved the traditional intraarticular injection and developed an intraarticular irrigation-injection therapy to treat 43 cases of TMJDS and got a good result. The controls include two groups, the simple rinsing and the traditional injection. Statistical analysis showed a highly significant difference in the effects between test and control groups. In order to study the mechanism of the therapy, the tumor necrosis factor (TNF) in synovial fluid of 8 cases were assessed. It was found that the concentration of TNF was reduced markedly after treatment. We think that the new therapy is effectable for TMJDS and could be used widely.
authors.affiliation: Department of Stomatology, First Teaching Hospital, Zhejang Medical University, Hangzhou.
authors.forename: Z
authors.initials: Z
authors.lastname: Gu
authors.forename: Q
authors.initials: Q
authors.lastname: Wu
authors.forename: Z
authors.initials: Z
authors.lastname: Cao
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007270:Injections, Intra-Articular; D008297:Male; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D013582:Synovial Fluid / Q000378:metabolism; D013704:Temporomandibular Joint / Q000378:metabolism; D013706:Temporomandibular Joint Dysfunction Syndrome / Q000378:metabolism / Q000628:therapy*; D007507:Therapeutic Irrigation; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
chemical_list: D000893:Anti-Inflammatory Agents; D014409:Tumor Necrosis Factor-alpha; D011239:Prednisolone