Endometriosis in monozygotic twins.
OBJECTIVE
To describe the occurrence of endometriosis in monozygotic twins.


METHODS
Postal questionnaire plus confirmation of disease status.


METHODS
Twins were recruited via the American Endometriosis Association and the National Endometriosis Society of Great Britain and via British gynecologists.


RESULTS
Fourteen twin pairs were concordant for endometriosis, and two were discordant. Nine pairs of twins had moderate-severe endometriosis.


CONCLUSIONS
These findings contribute to the growing body of literature that suggests endometriosis has a genetic basis.
Hadfield
R M
RM
Nuffield Department of Obstetrics and Gynaecology, University of Oxford, John Radcliffe Hospital, United Kingdom.
Mardon
H J
HJ
Barlow
D H
DH
Kennedy
S H
SH
D004200:Diseases in Twins; D004715:Endometriosis / Q000453:epidemiology* / Q000235:genetics / Q000473:pathology; D005260:Female; D006801:Humans; D014430:Twins, Monozygotic