title: Nucleotide sequence of the Staphylococcus aureus transposon, Tn5405, carrying aminoglycosides resistance genes.
abstract: Tn5405 is a 12 kb staphylococcal composite transposon delimited by two inverted copies of the insertion sequence IS1182. This transposon carries two aminoglycosides resistance genes, aphA-3 and aadE, an altered gene similar to sat4 from Campylobacter coli BE/G4, and three open reading frames of unknown functions.
authors.affiliation: National Reference Center for Staphylococci, Unité des Staphylocoques Institut Pasteur, Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Derbise
authors.forename: G
authors.initials: G
authors.lastname: de Cespedes
authors.forename: N
authors.initials: N
authors.lastname: el Solh
mesh_terms: D000595:Amino Acid Sequence; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001483:Base Sequence; D004251:DNA Transposable Elements; D004352:Drug Resistance, Microbial / Q000235:genetics*; D008969:Molecular Sequence Data; D013211:Staphylococcus aureus / Q000235:genetics*
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D004251:DNA Transposable Elements