[Prognostic factors in differentiated thyroid gland carcinoma].
This review aims at describing the influence of established and not yet sufficiently characterized parameters on the prognosis of thyroid follicle cell carcinomas. The analysis of literature data covers a broad spectrum of pathologic and biologic factors from classical prognostic features like age, gender and tumor stage to mutation, activation or, where applicable, inactivation of tumor suppressor genes, metastasis-related genes and adhesion molecules.
Fonseca
E
E
Institute of Molecular Pathology and Immunology, University of Porto (IPATIMUP) Medical Faculty, Hospital de S. João, Portugal.
Soares
P
P
Rossi
S
S
Sobrinho-Simões
M
M
D018263:Adenocarcinoma, Follicular / Q000145:classification / Q000235:genetics / Q000473:pathology; D014408:Biomarkers, Tumor / Q000235:genetics; D002277:Carcinoma / Q000145:classification / Q000235:genetics / Q000473:pathology; D018276:Carcinoma, Medullary / Q000145:classification / Q000235:genetics / Q000473:pathology; D002291:Carcinoma, Papillary / Q000145:classification / Q000235:genetics / Q000473:pathology; D004252:DNA Mutational Analysis; D016147:Genes, Tumor Suppressor / Q000235:genetics; D006801:Humans; D011379:Prognosis; D013961:Thyroid Gland / Q000473:pathology; D013964:Thyroid Neoplasms / Q000145:classification / Q000235:genetics / Q000473:pathology*
D014408:Biomarkers, Tumor