[A case of huge liver metastasis from colon cancer successfully treated by hepatic intraarterial infusion of low-dose 5-FU].
A 71-year-old man with unresectable liver metastasis from colon cancer was treated by hepatic intraarterial infusion of low dose 5-FU (250 mg/body/day). The tumor measured 18 cm by ultrasonography and has reduced gradually to five cm during three years. Both serum CEA and CA 19-9 levels were as high as 49.9 ng/ml and 5,500 U/ml respectively, before treatment, but normalized. This case suggested that this hepatic intraarterial infusion of low-dose 5-FU might be effective to treat unresectable liver metastasis, especially with portal tumor thrombosis.
Kameyama
M
M
First Dept. of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases.
Murata
K
K
Nakamori
S
S
Yasuda
T
T
Nakano
H
H
Ohigashi
H
H
Hiratsuka
M
M
Sasaki
Y
Y
Kabuto
T
T
Ishikawa
O
O
Furukawa
H
H
Imaoka
S
S
Fujita
M
M
D000368:Aged; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage*; D003110:Colonic Neoplasms / Q000473:pathology*; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage*; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000556:secondary*; D008297:Male; D009361:Neoplasm Invasiveness; D011168:Portal System / Q000473:pathology
D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil