Carvedilol overdose.
Carvedilol is a non selective beta-adrenoceptor antagonist which also causes peripheral vasodilation primarily via alpha 1-adrenergic blockade (Strein et al., 1987, McTavish et al., 1993). It has been shown effective in the treatment of mild-to-moderate hypertension and angina, and is currently under investigation in patients with congestive heart failure.
Hantson
P
P
Department of Intensive Care, Cliniques Universitaires St-Luc, Brussels, Belgium. hantson@rean.ucl.ac.be
Lambermont
J Y
JY
Simoens
G
G
Mahieu
P
P
D000319:Adrenergic beta-Antagonists / Q000506:poisoning*; D001794:Blood Pressure / Q000187:drug effects; D002227:Carbazoles / Q000506:poisoning*; D000077261:Carvedilol; D004298:Dopamine / Q000627:therapeutic use; D062787:Drug Overdose / Q000188:drug therapy / Q000503:physiopathology; D004562:Electrocardiography; D005260:Female; D006801:Humans; D007022:Hypotension / Q000139:chemically induced* / Q000188:drug therapy / Q000503:physiopathology; D007262:Infusions, Intravenous; D008875:Middle Aged; D011412:Propanolamines / Q000506:poisoning*; D013406:Suicide, Attempted
D000319:Adrenergic beta-Antagonists; D002227:Carbazoles; D011412:Propanolamines; D000077261:Carvedilol; D004298:Dopamine