[Determination of urinary excretion of iodine in cordarone induced hyperthyroidism].
It is well known that amiodarone, an antiarrythmic drug containing iodine, can induce in some subjects thyroid function alterations: hyperthyroidism in patients resident in iodine-deficient areas and hypothyroidism in those with sufficient iodine intake. We attempted in this study to show the possibility to select the subjects at major risk of this iodine-induced hyperthyroidism, with a simple and inexpensive method such as urinary excretion iodine assay.
Pepe
M
M
Dip. di Fisiopatologia Medica, Università degli Studi La Sapienza, Roma.
Graziano
F M
FM
Di Perna
P
P
Salvati
G
G
Reda
G
G
D000328:Adult; D000368:Aged; D000638:Amiodarone / Q000009:adverse effects / Q000627:therapeutic use*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000139:chemically induced* / Q000652:urine; D007037:Hypothyroidism / Q000139:chemically induced; D007455:Iodine / Q000652:urine*; D008297:Male; D008875:Middle Aged
D000889:Anti-Arrhythmia Agents; D007455:Iodine; D000638:Amiodarone