title: Hepatic coma recovered after interventional obliteration for ileocecal-inferior vena cava shunt--report of one case.
abstract: We performed interventional angiography (IVA) in a patient with liver cirrhosis (LC) and hepatoma (HCC) who experienced repeated attacks of unconsciousness due to hyperammonemia caused by ileocecal-inferior vena cava (IC-IVC) shunt and succeeded in the treatment. We report the results below. The patient, 53-year-old male, underwent endoscopic injection sclerotherapy for esophageal varix due to LC followed by splenectomy for pancytopenia in 1986. He made good progress. However intraarterial anticancer therapy was conducted for HCC in 1994. From that time hepatic coma began to appear and its frequency gradually increased. Hepatic coma occurred once every 3 weeks from June 1996. He was thus admitted to our hospital. Hematobiochemical testes showed that ammonia level was 297 mcg/dl. Albumin 2.8d/dl, and Total-Bilirubin 10.78 mg/dl. Arterioportography from superior mesenteric artery showed most of portal blood flowed away from the liver though the ileocolic vein to IVC. We decided to conduct IVA for treatment. Specially, a 6Fr balloon catheter was inserted from the right inguinal region into a shunt to the portal vein though IVC by the Seldinger technique. The balloon was inflated in the shunt to close the shunt. Six ml of 5% ethanolamime oleate with iopamidol was injected because retrograde angiography showed that iopamidol was flowed out via testicular vein to IVC. The balloon catheter was retained for 24 hours. Angiography, conducted from the catheter again 24 hours later, showed that the shunt was occluded, blood ammonia level was 71 mcg/dl after occlusion. Hepatic coma was not observed after treatment. We encountered a very rare case who repeated hepatic comas due to IC-IVC shunt and recovered dramatically after IVA.
authors.affiliation: Department of Surgery, Tsukuba Soai Hospital.
authors.forename: T
authors.initials: T
authors.lastname: Sawano
authors.forename: T
authors.initials: T
authors.lastname: Kawashima
authors.forename: Y
authors.initials: Y
authors.lastname: Takase
authors.forename: F
authors.initials: F
authors.lastname: Chikamori
authors.forename: S
authors.initials: S
authors.lastname: Shibuya
authors.forename: K
authors.initials: K
authors.lastname: Fukao
mesh_terms: D000792:Angiography; D001166:Arteriovenous Shunt, Surgical; D006528:Carcinoma, Hepatocellular / Q000150:complications / Q000000981:diagnostic imaging; D006501:Hepatic Encephalopathy / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000150:complications / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D011169:Portal Vein / Q000601:surgery*; D011172:Portography; D015641:Radiography, Interventional; D013927:Thrombosis / Q000209:etiology / Q000601:surgery*