title: Simple reaction time as a measure of global attention in Alzheimer's disease.
abstract: Alzheimer's disease (AD) is characterized by progressive decline in memory, language and other cognitive functions. Deficits in attentional processes have also been suggested. A simple reaction time (RT) task was used to assess global attention in AD. The length and consistency of a warning signal given prior to the response stimulus were manipulated to determine if patients with AD and age-matched controls benefit from predictability in RT tasks. Overall reaction time was slower in the AD group than in the and control group. Both groups demonstrated significant improvement in RT with long warning signals compared to short warning signals, but only the control group benefited from the consistency of the warning.
authors.affiliation: Department of Neurology in the Sergievsky Center, Columbia University College of Physicians and Surgeons, NY 10032, USA.
authors.forename: M
authors.initials: M
authors.lastname: Sano
authors.forename: W
authors.initials: W
authors.lastname: Rosen
authors.forename: Y
authors.initials: Y
authors.lastname: Stern
authors.forename: J
authors.initials: J
authors.lastname: Rosen
authors.forename: R
authors.initials: R
authors.lastname: Mayeux
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000175:diagnosis* / Q000523:psychology; D001288:Attention; D003463:Cues; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011930:Reaction Time; D012016:Reference Values