[Changes in the reactivity of the sensorimotor cortex resulting from the treatment of patients with depressive disorders].
Changes in the mu-rhythm power in response to sound (non-specific reactivity, NR) and related with the actual and imaginary movement with the right and left hand in response to sound (specific reactivity, SR) were studied in 38 right-handed patients with subdepressive psychogenic (PD) and endogenous (ED) disorders before and after successful complex treatment (pharmacotherapy and acupuncture) in comparison with 23 healthy subjects. The successful treatment was found to be accompanied by a certain extent of normalization of the disturbed SR which was different in PD and ED. The more complete recovery of the normal reactions in PD was mainly accounted for by the relative decrease in the NR and increase in the SR. The ED treatment predominantly modified the SR. Substantial reorganization of interhemispheric relations during movements in the PD patients resulted in disappearance of the abnormal ipsilateral reactions and transition to the contralateral reactions of the sensorimotor cortex.
Viatleva
O A
OA
Puchinskaia
L M
LM
Gorobets
L N
LN
D015670:Acupuncture Therapy; D000293:Adolescent; D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001714:Bipolar Disorder / Q000503:physiopathology / Q000628:therapy; D003863:Depression / Q000503:physiopathology* / Q000628:therapy; D003866:Depressive Disorder / Q000503:physiopathology / Q000628:therapy; D004292:Dominance, Cerebral / Q000187:drug effects / Q000502:physiology; D004359:Drug Therapy, Combination; D004569:Electroencephalography / Q000187:drug effects; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009044:Motor Cortex / Q000187:drug effects / Q000503:physiopathology*; D012559:Schizophrenia / Q000503:physiopathology / Q000628:therapy
D000928:Antidepressive Agents; D014150:Antipsychotic Agents