Value of intraoperative keratometry in predicting outcome of radial keratotomy.
OBJECTIVE
To investigate whether the immediate change in corneal power during radial keratotomy correlates with the long-term postoperative change in subjective refraction, and thereby being predictive for refractive outcome.


METHODS
Manual keratometry was performed on 45 consecutively operated eyes of 45 young persons with myopia of 5 dioptres and less and immediately after radial keratotomy. Automated keratometry and subjective spherical equivalent refraction were investigated during a follow-up period of 6 months and correlated to the intraoperative keratometric measurements.


RESULTS
On average, the majority of the change in corneal curvature after radial keratotomy took place within 1 min. There was no correlation between the intraoperative curvature change and the changes in curvature measured up to 6 months after surgery. There was a weak significant positive correlation between intraoperative curvature change and the change in subjective refraction at 6 months after surgery (R = 0.48, p < 0.01). The prediction error in estimating subjective refractive changes from intraoperative keratometry changes was, however, similar in patients who had bilateral radial keratotomy. Inclusion of such fellow-eye information together with the age of the patient in a multiple linear regression analysis increased the correlation coefficient from 0.48 to 0.75.


CONCLUSIONS
The change in central corneal curvature takes place within minutes after corneal incision. As a single parameter, intraoperative keratometry cannot be used for titrating surgery. Information from the results of first eye radial keratotomy surgery with intraoperative keratometry is, however, predictive for radial keratotomy in the second eye. These findings suggest that a large source to refractive variability after radial keratotomy is related to individual patient factors, such as corneal biomechanics and wound healing.
Olsen
H
H
Department of Ophthalmology, Arhus University Hospital, Denmark.
Ehlers
N
N
Hjortdal
J O
JO
D000328:Adult; D003315:Cornea / Q000473:pathology*; D005260:Female; D005544:Forecasting; D006801:Humans; D007432:Intraoperative Period; D007646:Keratotomy, Radial; D008297:Male; D009216:Myopia / Q000503:physiopathology / Q000601:surgery; D012029:Refraction, Ocular / Q000502:physiology; D012044:Regression Analysis; D016896:Treatment Outcome