title: Extra and central pontine myelinolysis in a child with adrenal insufficiency.
abstract: We report a 5-year-old patient with adrenal insufficiency (AI) who had a subacute monophasic neurologic illness and brainstem and striatal lesions on brain imaging. The prominent electrolyte abnormalities in AI indicate that extra and central pontine myelinolysis is the likely cause. An association between AI and extra pontine myelinolysis has not previously been reported in children.
authors.affiliation: Department of Child Neurology; P.D. Hinduja National Hospital & Medical Research Centre; Mumbai, India.
authors.forename: V P
authors.initials: VP
authors.lastname: Udani
authors.forename: V R
authors.initials: VR
authors.lastname: Dharnidharka
authors.forename: A R
authors.initials: AR
authors.lastname: Gajendragadkar
authors.forename: B
authors.initials: B
authors.lastname: D'Souza
mesh_terms: D000309:Adrenal Insufficiency / Q000175:diagnosis*; D000324:Adrenocorticotropic Hormone / Q000097:blood; D001933:Brain Stem / Q000473:pathology; D002675:Child, Preschool; D003342:Corpus Striatum / Q000473:pathology; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D008297:Male; D017590:Myelinolysis, Central Pontine / Q000175:diagnosis*; D009460:Neurologic Examination; D011149:Pons / Q000473:pathology; D014882:Water-Electrolyte Balance / Q000502:physiology
chemical_list: D000324:Adrenocorticotropic Hormone; D006854:Hydrocortisone