Dictyostelium development: lower STATs.
The discovery of a STAT protein in Dictyostelium indicates that this organism uses phosphotyrosine-SH2-domain signalling during development. Such signalling is lacking in yeast and its appearance may therefore be an early step in the evolution of multicellularity.
Kay
R R
RR
MRC Laboratory of Molecular Biology, Cambridge, UK.
D000818:Animals; D004268:DNA-Binding Proteins / Q000502:physiology*; D004023:Dictyostelium / Q000166:cytology / Q000254:growth & development* / Q000502:physiology; D015398:Signal Transduction / Q000502:physiology*; D015534:Trans-Activators / Q000502:physiology*
D004268:DNA-Binding Proteins; D015534:Trans-Activators