title: Successful intracoronary thrombolysis in cocaine-associated acute myocardial infarction.
abstract: We describe a case of cocaine-associated acute myocardial infarction managed by cardiac catheterization and intracoronary thrombolysis. Based on this and other reported cases, it appears that an invasive approach to the management of cocaine-associated acute myocardial infarction is advantageous over intravenous thrombolysis. Such a strategy would define the pathophysiology of acute myocardial infarction in the setting of cocaine use and allow mechanical intervention should pharmacologic therapy be unsuccessful.
authors.affiliation: Department of Medicine, Montefiore Medical Center, Bronx, New York, USA.
authors.forename: S S
authors.initials: SS
authors.lastname: Yao
authors.forename: H
authors.initials: H
authors.lastname: Spindola-Franco
authors.forename: M
authors.initials: M
authors.lastname: Menegus
authors.forename: M
authors.initials: M
authors.lastname: Greenberg
authors.forename: M
authors.initials: M
authors.lastname: Goldberger
authors.forename: J
authors.initials: J
authors.lastname: Shirani
mesh_terms: D000328:Adult; D003042:Cocaine / Q000009:adverse effects*; D019970:Cocaine-Related Disorders; D017023:Coronary Angiography; D004562:Electrocardiography; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000139:chemically induced* / Q000188:drug therapy; D010960:Plasminogen Activators / Q000627:therapeutic use*; D015912:Thrombolytic Therapy; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use*
chemical_list: D010960:Plasminogen Activators; D010959:Tissue Plasminogen Activator; D003042:Cocaine