Limb development: marginal fringe benefits.
Recent results show that in the developing Drosophila wing, the secreted pioneer protein Fringe regulates the sensitivity of the Notch signaling pathway to different ligands. This provides a likely mechanism by which Fringe-like molecules may control patterning in both Drosophila and vertebrates.
Blair
S S
SS
Department of Zoology, 250 N. Mills St., University of Wisconsin, Madison 53706, USA.
D000818:Animals; D004330:Drosophila / Q000235:genetics* / Q000254:growth & development*; D029721:Drosophila Proteins; D018507:Gene Expression Regulation, Developmental; D019476:Insect Proteins / Q000235:genetics; D017351:N-Acetylglucosaminyltransferases; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology*; D014921:Wings, Animal / Q000254:growth & development* / Q000502:physiology
D029721:Drosophila Proteins; D019476:Insect Proteins; D017351:N-Acetylglucosaminyltransferases; C090576:fng protein, Drosophila