Development of the kidney vasculature.
Renal vascularization and nephrogenesis occur simultaneously following a tightly regulated developmental program influenced by growth factors, extracellular matrix components and cell membrane receptors. Both processes of angiogenesis and vasculogenesis probably participate in the formation of renal vessels. The origin and fate of the various renal vascular cells and the molecular mechanisms that initiate and guide intrarenal vascularization are fundamental questions that remain to be answered.
Gomez
R A
RA
University of Virginia School of Medicine, Department of Pediatrics, Charlottesville 22908, USA.
Norwood
V F
VF
Tufro-McReddie
A
A
D000818:Animals; D001808:Blood Vessels / Q000196:embryology; D006801:Humans; D007668:Kidney / Q000098:blood supply* / Q000196:embryology*; D009024:Morphogenesis; D018919:Neovascularization, Physiologic