title: [A case of infiltration of scar of sarcoidosis after blepharoplasty].
abstract: A case of a 28-year-old woman with infiltration of sarcoidosis scar tissue after blepharoplasty is reported. Nodules developed two times in her right upper eyelid about 1 and 2 years after blepharoplasty of both eyes and they were resected each time, but eruption recurred. Ophthalmic examination revealed aqueous flare and cells, snowball vitreous opacities, and retinal periphlebitis. A chest X-ray disclosed bilateral hilar lymphadenopathy (BHL). Laboratory studies showed an elevation of the serum angiotensin converting enzyme (ACE). Light microscopy revealed epithelioid granuloma with no caseation necrosis in a biopsy specimen, Viewing through polarized light demonstrated crystalline-like foreign bodies with bi-refringence in the epithelioid granuloma. Electron microscopic X-ray microanalysis confirmed these foreign bodies to be composed of Si, Mg, and O. These findings indicate that this skin lesion was caused by an infiltration of sarcoidosis scar tissue.
authors.affiliation: Department of Ophthalmology, Itabashi-ku Medical Association Hospital, Japan.
authors.forename: J
authors.initials: J
authors.lastname: Takahashi
authors.forename: T
authors.initials: T
authors.lastname: Morishima
authors.forename: Y
authors.initials: Y
authors.lastname: Satoh
authors.forename: S
authors.initials: S
authors.lastname: Hashimoto
mesh_terms: D000328:Adult; D019882:Blepharoplasty / Q000009:adverse effects*; D002921:Cicatrix / Q000150:complications* / Q000473:pathology; D004577:Electron Probe Microanalysis; D005141:Eyelid Diseases / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008274:Magnesium / Q000032:analysis; D010100:Oxygen / Q000032:analysis; D012507:Sarcoidosis / Q000209:etiology* / Q000473:pathology; D012825:Silicon / Q000032:analysis; D012871:Skin Diseases / Q000209:etiology* / Q000473:pathology
chemical_list: D008274:Magnesium; D010100:Oxygen; D012825:Silicon