Lung transplantation in cystic fibrosis.
Since the mid-1980s, more than 500 isolated lung and more than 240 heart-lung transplantations have been performed in patients with cystic fibrosis and end-stage disease. Survival data in these patients are now comparable to those of the general transplantation population as physicians have learned to deal successfully with many issues unique to patients with cystic fibrosis. Resistant infections and bronchiolitis obliterans remain significant obstacles to overcome in order to improve patients outcomes and enhance posttransplant quality of life.
Maurer
J R
JR
Department of Pulmonary and Critical Care Medicine, Cleveland Clinic Foundation, OH 44195, USA.
Chaparro
C
C
D000328:Adult; D001989:Bronchiolitis Obliterans; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000601:surgery*; D016041:Heart-Lung Transplantation; D006801:Humans; D016040:Lung Transplantation; D018579:Patient Selection; D011183:Postoperative Complications