title: Laparoscopic repair of perforated duodenal ulcer. A prospective multicenter clinical trial.
abstract: BACKGROUND
  A series of 100 consecutive patients with perforated peptic ulcer were prospectively evaluated in a multicenter study. The feasibility of the laparoscopic repair was evaluated.
  
  
  METHODS
  All patients had peritonitis, 20% were in septic shock, and 57% had delayed perforation. Conversion to laparotomy was necessary in eight patients. The morbidity rate was 9% and mortality rate 5%.
  
  
  RESULTS
  The mean delay of postoperative gastric aspiration (mean 3.4 days) and resumed food intake (mean 4.4 days) as well as the mean postoperative hospital stay (mean 9.3 days) were comparable to conventional surgery, but postoperative comfort was subjectively increased by laparoscopy and noticed by all laparoscopic surgeons participating in this study.
  
  
  CONCLUSIONS
  Laparoscopic repair of perforated peptic ulcer proves to be technically feasable and carries an acceptable morbidity and mortality rate, compared with conventional surgery.
authors.affiliation: Medical and Surgical Unit of Gastroenterology, Hospital Center Etterbeeck-CHEI, Brussels, Belgium.
authors.forename: M L
authors.initials: ML
authors.lastname: Druart
authors.forename: R
authors.initials: R
authors.lastname: Van Hee
authors.forename: J
authors.initials: J
authors.lastname: Etienne
authors.forename: G B
authors.initials: GB
authors.lastname: Cadière
authors.forename: J F
authors.initials: JF
authors.lastname: Gigot
authors.forename: M
authors.initials: M
authors.lastname: Legrand
authors.forename: J M
authors.initials: JM
authors.lastname: Limbosch
authors.forename: B
authors.initials: B
authors.lastname: Navez
authors.forename: M
authors.initials: M
authors.lastname: Tugilimana
authors.forename: E
authors.initials: E
authors.lastname: Van Vyve
authors.forename: L
authors.initials: L
authors.lastname: Vereecken
authors.forename: E
authors.initials: E
authors.lastname: Wibin
authors.forename: J P
authors.initials: JP
authors.lastname: Yvergneaux
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004381:Duodenal Ulcer / Q000150:complications*; D005260:Female; D006801:Humans; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D010439:Peptic Ulcer Perforation / Q000209:etiology / Q000601:surgery*; D011183:Postoperative Complications; D011446:Prospective Studies; D015996:Survival Rate