title: Comparison of mRAST and CAP with skin end point titration for Alternaria tenuis and dermatophagoides pteronyssinus.
abstract: There has been a recent explosion of new in vitro tests for the diagnosis of allergies. At present there is no general agreement on which type of in vitro test is best. Recently our hospital switched in vitro testing from the modified radioallergosorbent system (mRAST) to the Pharmacia CAP system (CAP). While changing in vitro testing techniques, 47 patients were tested with both the mRAST and CAP tests. Comparisons were made between the mRAST and CAP results of Alternaria tenuis and Dermatophagoides pteronyssinus allergens. These results were then compared with the results of patients who also underwent intradermal skin testing based on end point titration techniques.
authors.affiliation: Division of Otolaryngology, University of Missouri, Columbia, USA.
authors.forename: D W
authors.initials: DW
authors.lastname: Chambers
authors.forename: P R
authors.initials: PR
authors.lastname: Cook
authors.forename: G J
authors.initials: GJ
authors.lastname: Nishioka
authors.forename: P
authors.initials: P
authors.lastname: Erhart
mesh_terms: D000485:Allergens / Q000032:analysis*; D000528:Alternaria / Q000276:immunology*; D000818:Animals; D000941:Antigens / Q000032:analysis; D039741:Antigens, Dermatophagoides; D000946:Antigens, Fungal / Q000032:analysis; D003546:Cysteine Endopeptidases / Q000032:analysis; D005188:False Negative Reactions; D005189:False Positive Reactions; D006023:Glycoproteins / Q000032:analysis; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis; D007163:Immunosorbent Techniques; D008925:Mites / Q000276:immunology*; D011852:Radioallergosorbent Test; D012221:Rhinitis, Allergic, Perennial / Q000175:diagnosis; D012680:Sensitivity and Specificity; D015927:Skin Test End-Point Titration
chemical_list: D000485:Allergens; D000941:Antigens; D039741:Antigens, Dermatophagoides; D000946:Antigens, Fungal; D006023:Glycoproteins; D003546:Cysteine Endopeptidases