Natural killer cells: influence of the home environment.
Recent results show that the repertoire of anti-MHC class 1-specific inhibitory receptors expressed by natural killer cells is influenced by self class 1 molecules in such a way as to minimize the number of cells with multiple self-reactive inhibitory receptors.
Gascoigne
N R
NR
Department of Immunology, Scripps Research Institute, La Jolla, California 92037, USA.
D000818:Animals; D000950:Antigens, Ly; D002352:Carrier Proteins / Q000235:genetics / Q000502:physiology*; D005786:Gene Expression Regulation; D006183:H-2 Antigens / Q000502:physiology; D007694:Killer Cells, Natural / Q000276:immunology*; D037181:Lectins, C-Type; D008565:Membrane Proteins / Q000235:genetics / Q000502:physiology*; D055630:Receptors, NK Cell Lectin-Like; D017634:Self Tolerance; D001613:beta 2-Microglobulin / Q000235:genetics / Q000502:physiology
D000950:Antigens, Ly; D002352:Carrier Proteins; D006183:H-2 Antigens; D037181:Lectins, C-Type; D008565:Membrane Proteins; D055630:Receptors, NK Cell Lectin-Like; D001613:beta 2-Microglobulin