title: [Electrochemical regeneration of dialysis solution in experimental and clinical conditions].
abstract: The authors have created a new system for electrochemical regeneration of dialysis solution and conducted 67 experiments using a model solution. Two groups of patients with terminal renal failure were treated. The regeneration system was applied in the treatment of Group 1 patients (n = 14), the traditional acetate hemodialysis procedure was used in Group 2 (n = 11). Hemodialysis with electrochemical regeneration of dialysis fluid removed creatinine and potassium ions from critically ill patients' blood as effectively as the traditional hemodialysis procedure. During electrochemical hemodialysis, middle-molecular toxins were removed better those with the traditional one, but urea and inorganic phosphorus were eliminated slowler. Electrochemical regeneration provided continuous purification of dialysis fluid. The regenerator block can be used many times. Sodium hypochlorite ensured self-sterilization of the system. The use of electrochemical regeneration does not require water purification, water communications and dialysis concentrate, which enables the detoxification procedure to be performed outside the specially equipped rooms.
authors.affiliation: Scientific Center of Surgery RAMN, Moscow.
authors.forename: V L
authors.initials: VL
authors.lastname: Eventov
authors.forename: M I
authors.initials: MI
authors.lastname: Andrianova
authors.forename: V A
authors.initials: VA
authors.lastname: Maksimenko
authors.forename: S I
authors.initials: SI
authors.lastname: Nefedkin
authors.forename: T
authors.initials: T
authors.lastname: Ostodi
mesh_terms: D000818:Animals; D003956:Dialysis / Q000379:methods*; D015314:Dialysis Solutions; D004563:Electrochemistry / Q000379:methods*; D006801:Humans; D051437:Renal Insufficiency / Q000628:therapy
chemical_list: D015314:Dialysis Solutions