Five year treatment with IGF-I of a patient with Laron syndrome in Slovenia (a follow-up report).
This is a follow-up report of a 14 1/2 year-old boy with Laron syndrome, who received twice daily therapy with IGF-I 120 micrograms/kg for 5 years that resulted in a linear growth of 40 cm. Concomitantly he became very obese which is attributed to IGF-I action via the insulin receptors.
Krzisnik
C
C
Department of Paediatrics, University Medical Centre Ljubljana, Slovenia.
Battelino
T
T
D000886:Anthropometry; D001827:Body Height; D002648:Child; D005500:Follow-Up Studies; D006130:Growth Disorders / Q000188:drug therapy*; D006801:Humans; D007334:Insulin-Like Growth Factor I / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D009154:Mutation; D011628:Puberty, Delayed; D011986:Receptors, Somatotropin / Q000235:genetics*; D011994:Recombinant Proteins / Q000627:therapeutic use; D017524:Slovenia; D013577:Syndrome
D011986:Receptors, Somatotropin; D011994:Recombinant Proteins; D007334:Insulin-Like Growth Factor I