Peroxisome proliferator activated receptors: transcriptional regulators of adipogenesis, lipid metabolism and more....
The recent discovery of lipid-activatable transcription factors that regulate the genes controlling lipid metabolism and adipogenesis has provided insight into the way that organisms sense and respond to lipid levels. Identification of the signaling pathways in which these receptors are involved will help us to understand the control of energy balance and the molecular defects underlying its disorders.
Wahli
W
W
Glaxo Institute for Molecular Biology, Geneva, Switzerland.
Braissant
O
O
Desvergne
B
B
D000273:Adipose Tissue / Q000502:physiology*; D000818:Animals; D004734:Energy Metabolism; D005786:Gene Expression Regulation / Q000235:genetics / Q000502:physiology; D006801:Humans; D050356:Lipid Metabolism; D008055:Lipids / Q000235:genetics; D018160:Receptors, Cytoplasmic and Nuclear / Q000235:genetics / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology; D014157:Transcription Factors / Q000235:genetics / Q000502:physiology*; D014158:Transcription, Genetic / Q000235:genetics / Q000502:physiology*
D008055:Lipids; D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors