Vancomycin-resistant Staphylococcus aureus: an emerging public health threat.
Three reported cases of infection with strains of Staphylococcus aureus that had only intermediate susceptibility to vancomycin raise fears that high-level vancomycin resistance may soon be seen. To forestall this occurrence, physicians need to limit their use of vancomycin, and hospitals need to intensify their infection-control efforts. We review treatment options and the recommendations from the Centers for Disease Control and Prevention to identify and slow the spread of resistant strains.
Flores
P A
PA
Department of Hospital Pharmacy, Cleveland Clinic Foundation, OH 44195, USA.
Gordon
S M
SM
D000328:Adult; D003140:Communicable Disease Control; D004352:Drug Resistance, Microbial; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D009820:Ohio; D017410:Practice Guidelines as Topic; D011634:Public Health; D013203:Staphylococcal Infections / Q000517:prevention & control*; D013211:Staphylococcus aureus / Q000187:drug effects*; D014640:Vancomycin / Q000494:pharmacology* / Q000627:therapeutic use
D014640:Vancomycin