Nitric oxide is not increased in alcoholic brain.
Nitric oxide (NO) metabolites nitrite and nitrate were measured in the cerebrospinal fluid in 12 alcohol-dependent subjects and in 16 healthy controls. The amounts of NO metabolites in alcoholics were not different from those in the controls. The results suggest that NO is not a major factor responsible for brain damage in these patients.
Neiman
J
J
Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
Benthin
G
G
D000428:Alcohol Drinking; D000437:Alcoholism / Q000134:cerebrospinal fluid / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D001923:Brain Chemistry; D006801:Humans; D009566:Nitrates / Q000134:cerebrospinal fluid; D009569:Nitric Oxide / Q000378:metabolism*; D009573:Nitrites / Q000134:cerebrospinal fluid; D013695:Temperance
D009566:Nitrates; D009573:Nitrites; D009569:Nitric Oxide