[Authors' experience with transvaginal administration of progestagens].
The authors, after a short introducing on the most used kinds of progestins in Hormonal Replacement Therapy (HRT), report this own clinical experience on the efficacy of a micronized progestin treatment given by the vaginal route in comparison with oral somministration, studying in details the protective effects on endometrial hyperplasia and cancer. The role of danazolo on the hormonal balance during HRT has been also evaluated. The results suggest a positive effects of the vaginal somministration of micronized HRT progesterone or danazolo.
Cataldi
U
U
I Istituto di Clinica Ostetrica e Ginecologica, Università degli Studi di Roma La Sapienza.
Tridente
V
V
Pazienza
S
S
Brizzi
C
C
Serrao
L
L
Proia
L
L
Quattrini
M J
MJ
D000328:Adult; D003613:Danazol / Q000008:administration & dosage*; D004965:Estrogen Antagonists / Q000008:administration & dosage / Q000494:pharmacology; D015914:Estrogen Replacement Therapy / Q000379:methods; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000139:chemically induced; D008875:Middle Aged; D011374:Progesterone / Q000008:administration & dosage* / Q000009:adverse effects; D011372:Progestins / Q000008:administration & dosage* / Q000009:adverse effects; D016312:Treatment Refusal; D014621:Vagina
D004965:Estrogen Antagonists; D011372:Progestins; D011374:Progesterone; D003613:Danazol