[Anti-herpes virus action of ethanol-extract from the root and rhizome of Rheum officinale Baill].
The study has shown that the cytotoxity of ethanol-extract from the root and rhizome of Rheum of ficinale is very low. It shows no cytotoxity even at 20,000 micrograms/ml and on the contrary tends to promote cell growth. Obvious anti-viral action can be observed in cell culture. The minimum inhibition dose for herpes simplex virus (HSV) is 100 micrograms/ml. Also, the extract helps to prevent cells from viral infections and has some direct effect on viral particles.
Wang
Z
Z
Institute of Pharmacy, Shandong Academy of Medical Sciences, Jinan.
Wang
G
G
Xu
H
H
Wang
P
P
D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D006367:HeLa Cells; D006801:Humans; D007668:Kidney / Q000166:cytology; D010946:Plants, Medicinal; D011817:Rabbits; D012250:Rheum; D018139:Simplexvirus / Q000187:drug effects / Q000502:physiology*; D014779:Virus Replication / Q000187:drug effects*
D000998:Antiviral Agents; D004365:Drugs, Chinese Herbal