[The population genetic aspects of the intestinal microbiological phenotype in healthy humans].
The principle of the formation of the microbiological phenotype in the intestine of healthy persons was studied by the method of the population-genetic analysis. The microbial composition of the intestinal flora of healthy members of 10 complete families (altogether 50 persons) was studied. The study revealed that practically in all cases the variability of the qualitative and quantitative characteristics of the phenotype under study on the levels of both genera and individual microbial species is formed mainly under the influence of environmental factors. The presence of indigenous bacteria in the intestinal microbiocenosis (including Escherichia coli with normal enzymatic properties) is strongly genetically determined.
Vorob'ev
A A
AA
Nesvizhskiĭ
Iu V
IuV
Budanova
E V
EV
Inozemtseva
L O
LO
D000293:Adolescent; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D001419:Bacteria / Q000145:classification / Q000302:isolation & purification; D002648:Child; D005243:Feces / Q000382:microbiology; D005260:Female; D014644:Genetic Variation; D005828:Genetics, Population; D005838:Genotype; D006801:Humans; D007422:Intestines / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D012016:Reference Values