title: Sexual factors associated with cytomegalovirus seropositivity in human immunodeficiency virus-infected men. The Seroco Study Group.
abstract: BACKGROUND
  Many people infected by human immunodeficiency virus (HIV) acquire severe cytomegalovirus (CMV) diseases. Factors associated with CMV seropositivity are poorly documented in sexually active HIV-infected men.
  
  
  OBJECTIVE
  To study CMV seroprevalence in HIV-infected men according to sexual behavior before the diagnosis of HIV seropositivity.
  
  
  METHODS
  Cross-sectional study. CMV seroprevalence was studied at enrollment in a prospective cohort of homosexual and heterosexual men infected by HIV through sexual contact.
  
  
  RESULTS
  In the study population (n = 723), age, sexual preference, previous lifetime history of sexually transmitted diseases, and multiple sexual partners were independently related to CMV seropositivity. Furthermore, routine condom use during the 6 months before diagnosis of HIV seropositivity was significantly related to CMV seropositivity (adjusted odds ratio [OR]: 0.4, 95% confidence interval [CI]: 0.1-1.0), occasional condom use being of borderline significance [adjusted OR: 0.5, CI: 0.2-1.3].
  
  
  CONCLUSIONS
  This study confirms the importance of sexual factors in the acquisition of CMV infection by HIV-infected men and suggests a protective effect of condom use.
authors.affiliation: Department of Public Health/Epidemiology/Human Reproduction at INSERM 292 (Institut National de la Santé et de la Recherche Médicale), Paris, France.
authors.forename: N
authors.initials: N
authors.lastname: Carré
authors.forename: M
authors.initials: M
authors.lastname: Robain
authors.forename: E
authors.initials: E
authors.lastname: Dussaix
authors.forename: D
authors.initials: D
authors.lastname: Salmon-Ceron
authors.forename: L
authors.initials: L
authors.lastname: Meyer
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000209:etiology*; D000328:Adult; D000367:Age Factors; D000914:Antibodies, Viral / Q000097:blood; D003430:Cross-Sectional Studies; D003586:Cytomegalovirus Infections / Q000209:etiology*; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012725:Sexual Behavior
chemical_list: D000914:Antibodies, Viral