title: [Effect of controlled hypotension induced by prostaglandin E1 on evoked spinal cord potential and spinal cord blood flow].
abstract: We evaluated the effect of controlled hypotension induced by PGE1 on evoked spinal cord potential (ESCP) and spinal cord blood flow (SCBF) in 14 patients undergoing laminectomy or laminoplasty. They were divided into two groups: hypotensive group (group H), non-hypotensive group (group N). Controlled hypotension was induced with PGE1 to maintain mean arterial blood pressure at 55-60 mmHg for 45 min. The amplitude and latency of the N 1 potential were analyzed, and the SCBF was estimated by laser doppler flowmeter. There were no significant differences in ESCP and SCBF. These results suggest that controlled hypotension by PGE1 maintained normal local spinal cord blood flow autoregulation.
authors.affiliation: Department of Anesthesia, Nagasaki Rosai Hospital, Sasebo.
authors.forename: R
authors.initials: R
authors.lastname: Ide
authors.forename: M
authors.initials: M
authors.lastname: Fukusaki
authors.forename: K
authors.initials: K
authors.lastname: Yamaguchi
authors.forename: M
authors.initials: M
authors.lastname: Matsumoto
authors.forename: K
authors.initials: K
authors.lastname: Ogata
authors.forename: K
authors.initials: K
authors.lastname: Sumikawa
mesh_terms: D000368:Aged; D000527:Alprostadil; D005071:Evoked Potentials; D005260:Female; D006706:Homeostasis; D006801:Humans; D007023:Hypotension, Controlled; D007796:Laminectomy; D008297:Male; D008875:Middle Aged; D012039:Regional Blood Flow; D013116:Spinal Cord / Q000098:blood supply* / Q000502:physiology*
chemical_list: D000527:Alprostadil