title: [Results of therapy for osteogenic sarcoma in children: perspectives of improvement].
abstract: A retrospective analysis of treatment of 67 children suffering localized osteogenic sarcoma received at the Institute's Clinic (1977-1995) has been carried out. The best 5-year survival results were obtained with the COSS-91 and PECOSS programs and those for pre- and post-operative COMBAP chemotherapy (77.8 and 70.0%, respectively). Another randomized comparative study of the effectiveness of different polychemotherapy and pre-operative radiation schedules are being planned.
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Punanov
authors.forename: A P
authors.initials: AP
authors.lastname: Malinin
authors.forename: S A
authors.initials: SA
authors.lastname: Safonova
authors.forename: T D
authors.initials: TD
authors.lastname: Viktorovich
authors.forename: G I
authors.initials: GI
authors.lastname: Gafton
authors.forename: E I
authors.initials: EI
authors.lastname: Darskaia
authors.forename: S A
authors.initials: SA
authors.lastname: Malikov
authors.forename: B A
authors.initials: BA
authors.lastname: Kolygin
mesh_terms: D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D012516:Osteosarcoma / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D012189:Retrospective Studies; D016019:Survival Analysis; D016896:Treatment Outcome