An unusual poisoning with the unusual pesticide amitraz.
Amitraz, 1,5 di-(2,4-dimethylphenyl)-3-methyl-1,3,5-triaza-penta-1,4-diene, a formamidine pesticide, is used worldwide. It causes side-effects in animals that resemble those caused by pure alpha 2-adrenergic agonist drugs such as clonidine. Data on poisonings in humans are scanty. We report on a case of human poisoning with amitraz with typical signs of alpha 2-adrenoreceptor stimulation.
Jorens
P G
PG
Department of Intensive Care Medicine, University Hospital of Antwerp, Edegem, Belgium.
Zandijk
E
E
Belmans
L
L
Schepens
P J
PJ
Bossaert
L L
LL
D001794:Blood Pressure / Q000187:drug effects; D001919:Bradycardia / Q000139:chemically induced; D003128:Coma / Q000139:chemically induced; D006339:Heart Rate / Q000187:drug effects; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D008297:Male; D008875:Middle Aged; D018341:Receptors, Adrenergic, alpha-2 / Q000187:drug effects; D014052:Toluidines / Q000097:blood / Q000493:pharmacokinetics / Q000506:poisoning*
D007306:Insecticides; D018341:Receptors, Adrenergic, alpha-2; D014052:Toluidines; C014983:amitraz