title: Complications of absorbable pelvic mesh slings following surgery for rectal carcinoma.
abstract: OBJECTIVE
  To evaluate the intraoperative, postoperative, and long-term complications of an absorbable pelvic mesh sling after surgery for rectal carcinoma.
  
  
  METHODS
  A retrospective review of medical records from April 8, 1991, through April 8, 1996.
  
  
  RESULTS
  Twenty patients with a mean age of 57 (range, 37-79) years underwent pelvic mesh sling placement. The tumor stages were as follows: Stage I, 5; Stage II, 2; Stage III, 11; and Stage IV, 1. A recurrent perianal basal cell carcinoma was not included in the staging group. Surgery consisted of 18 abdominoperineal resections, 1 total proctocolectomy, and one Hartmann's procedure. Mean follow-up was 18 (range, 2-49) months. There were no intraoperative complications related to mesh placement. Twenty-nine complications occurred in 14 patients during the immediate postoperative period. Five were possibly mesh-related and included a pelvic abscess, perineal seroma, toxic perineal wound, pulmonary embolus, and lower extremity deep venous thrombosis, respectively. A mild postoperative ileus developed in 17 patients (85 percent), and a diet was initiated at a mean of seven (range, 4-24) days. Fourteen patients received postoperative radiotherapy with a mean dose of 5,339 (range, 2,500-7,020) cGy delivered in 180-cGy fractions. There were 14 immediate complications caused by radiotherapy in 11 patients, but only two patients required delays in treatment. Two patients had diarrhea alone, six developed perineal dermatitis alone, and three patients had both diarrhea and perineal dermatitis. All patients with diarrhea had received chemoradiation. One patient developed a partial small-bowel obstruction following radiation.
  
  
  CONCLUSIONS
  Absorbable pelvic mesh sling placement can be performed with minimum morbidity and is recommended following surgery for rectal cancer when radiation is anticipated as part of multimodality therapy.
authors.affiliation: Division of Surgical Oncology and Endoscopy, Roswell Park Cancer Institute, State University of New York at Buffalo 14263, USA.
authors.forename: A
authors.initials: A
authors.lastname: Beitler
authors.forename: M A
authors.initials: MA
authors.lastname: Rodriguez-Bigas
authors.forename: T K
authors.initials: TK
authors.lastname: Weber
authors.forename: R J
authors.initials: RJ
authors.lastname: Lee
authors.forename: R
authors.initials: R
authors.lastname: Cuenca
authors.forename: N J
authors.initials: NJ
authors.lastname: Petrelli
mesh_terms: D000230:Adenocarcinoma / Q000532:radiotherapy* / Q000601:surgery*; D000328:Adult; D000368:Aged; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007421:Intestine, Small; D008297:Male; D008875:Middle Aged; D010388:Pelvis; D011100:Polyglycolic Acid; D011183:Postoperative Complications; D011832:Radiation Injuries / Q000517:prevention & control*; D018714:Radiotherapy, Adjuvant / Q000009:adverse effects; D012004:Rectal Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D012007:Rectum / Q000601:surgery; D012189:Retrospective Studies; D013526:Surgical Mesh / Q000009:adverse effects*
chemical_list: D011100:Polyglycolic Acid