title: Genome sequences: genome sequence of a model prokaryote.
abstract: The complete Escherichia coli genome sequence is now known; it should greatly facilitate the analysis of other genomes, but a lot remains to be learnt about E. coli itself. About half the genes were previously uncharacterized, but expanding databases and improving analysis methods will help predict their functions.
authors.affiliation: National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894, USA.
authors.forename: E V
authors.initials: EV
authors.lastname: Koonin
mesh_terms: D001426:Bacterial Proteins / Q000737:chemistry / Q000235:genetics; D017124:Conserved Sequence; D004926:Escherichia coli / Q000235:genetics*; D016680:Genome, Bacterial; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
chemical_list: D001426:Bacterial Proteins