Intraoperative functional MRI using a real-time neurosurgical navigation system.
A 42-year-old-man had focal left hand motor seizures. MR studies demonstrated a right posterior frontal brain tumor. Functional MRI was performed, localizing the motor cortex posterior to the lesion. The functional images were integrated with a neurosurgical navigation computer. A real-time intraoperative display of the anatomic and functional images was produced, registered to a neurosurgical probe. Excellent correlation was demonstrated between the functional maps and invasive electrophysiologic mapping performed at the time of craniotomy.
Maldjian
J A
JA
Department of Radiolgy, UMDNJ-New Jersey Medical School, Newark, USA.
Schulder
M
M
Liu
W C
WC
Mun
I K
IK
Hirschorn
D
D
Murthy
R
R
Carmel
P
P
Kalnin
A
A
D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis / Q000601:surgery*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007432:Intraoperative Period; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009044:Motor Cortex / Q000473:pathology*