Treatment of arterial thromboembolic disease.
Prevention of thrombus formation and embolization remains a therapeutic challenge. Recent advances in the treatment of arterial thromboembolic disease include prevention of thromboembolism in patients with nonrheumatic atrial fibrillation with warfarin or aspirin, and combined therapy with low-dose aspirin, and anticoagulants for prosthetic heart valves and coronary artery disease. The potential of direct thrombin inhibition for treatment of acute coronary syndromes is also discussed.
Meyer
B J
BJ
University Hospital, Berne, Switzerland.
Chesebro
J H
JH
D001157:Arterial Occlusive Diseases / Q000188:drug therapy*; D001281:Atrial Fibrillation / Q000150:complications / Q000188:drug therapy; D002986:Clinical Trials as Topic; D003327:Coronary Disease / Q000150:complications / Q000188:drug therapy; D006350:Heart Valve Prosthesis / Q000009:adverse effects; D006801:Humans; D013923:Thromboembolism / Q000188:drug therapy* / Q000209:etiology; D015912:Thrombolytic Therapy