title: Assessment of the esophageal wall by endoscopic ultrasonography in patients with nutcracker esophagus.
abstract: BACKGROUND
  The correlation between the width of muscularis propria and esophageal pressure in patients with the nutcracker esophagus is unknown. We examined by endoscopic ultrasonography the width of the muscularis propria in patients with nutcracker esophagus.
  
  
  METHODS
  The width of muscularis propria was measured at the gastroesophageal junction and at the lower, middle, and upper esophagus in 18 patients and 10 control subjects.
  
  
  RESULTS
  Mean muscularis propria diameter in patients was 1.8 +/- 1.4, 1.5 +/- 1.2, 1.5 +/- 0.8, and 1.2 +/- 0.4 mm at the gastroesophageal junction, lower, middle, and upper esophagus. In the control group, the mean width was 1.2 +/- 0.3, 1.2 +/- 0.3, 1.1 +/- 0.3, and 0.9 +/- 0.1 mm, respectively. The difference was significant at the gastroesophageal junction and upper esophagus. The muscularis propria was wider than 3 mm in 30% of patients. There was no correlation between the site of the wide muscularis propria and the esophageal segment where high pressure was recorded. Length of disease, frequency of symptoms, and length of each symptomatic period did not correlate with the width of muscularis propria.
  
  
  CONCLUSIONS
  The muscularis propria is thickened in one third of patients with nutcracker esophagus. The extent and magnitude of this thickening do not correspond to the location and the magnitude of the manometric abnormality or clinical presentation.
authors.affiliation: Department of Gastroenterology Sheba, Wolfson Medical Center, Tel Aviv University, Israel.
authors.forename: E
authors.initials: E
authors.lastname: Melzer
authors.forename: Y
authors.initials: Y
authors.lastname: Ron
authors.forename: E
authors.initials: E
authors.lastname: Tiomni
authors.forename: Y
authors.initials: Y
authors.lastname: Avni
authors.forename: S
authors.initials: S
authors.lastname: Bar-Meir
mesh_terms: D000328:Adult; D000368:Aged; D019160:Endosonography; D015154:Esophageal Motility Disorders / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D009130:Muscle, Smooth / Q000000981:diagnostic imaging; D011312:Pressure