[The immunology of cholera and the molecular biology of cholera toxin. Recent progress and future perspectives].
Vibrio cholerae has recently called the attention of researchers due to its strong immunogenicity and also because it serves as coadjunct immunomodulator of the immune response of the intestinal mucosae for the mixed added antigens as well as for those covalently linked to the toxin. The immunopathogeny of cholera is a complex phenomenon. This article presents the preliminary results of experiments conducted with laboratory rats in order to find the IgA intestinal response of rodents and humans.
Carrada-Bravo
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Hospital General de Zona No. 2 IMSS. Irapuato, Gto. México.
D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis / Q000276:immunology*; D002771:Cholera / Q000276:immunology*; D002772:Cholera Toxin / Q000737:chemistry / Q000235:genetics / Q000276:immunology* / Q000633:toxicity; D022121:Cholera Vaccines / Q000276:immunology; D006801:Humans; D007070:Immunoglobulin A / Q000096:biosynthesis / Q000276:immunology*; D007413:Intestinal Mucosa / Q000276:immunology*; D008958:Models, Molecular; D011487:Protein Conformation; D051381:Rats; D014734:Vibrio cholerae / Q000235:genetics / Q000276:immunology*
D000907:Antibodies, Bacterial; D022121:Cholera Vaccines; D007070:Immunoglobulin A; D002772:Cholera Toxin