DNA topology: topoisomerases keep it simple.
The ability of type II DNA topoisomerases to perturb the equilibrium distributions of DNA topoisomers is a consequence of their ability to hydrolyse ATP. A sliding mechanism of topoisomerase action has been proposed to account for this phenomenon.
Bates
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School of Biological Sciences, University of Liverpool, Life Sciences Building, Crown Street, Liverpool L69 7ZB, UK. bates@liv.ac.uk
Maxwell
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A
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D004247:DNA / Q000737:chemistry / Q000378:metabolism*; D004250:DNA Topoisomerases, Type II / Q000378:metabolism*; D009690:Nucleic Acid Conformation
D000255:Adenosine Triphosphate; D004247:DNA; D004250:DNA Topoisomerases, Type II