[Algorithmic support of a laboratory bed for testing geroprotectors and geropromoters].
The paper proposes a mathematical model of development of a cell population with a changing proliferative activity. The model is based on the Markov branching process with cells of several types. A procedure for identifying the constructed model by experimental evidence is being developed. An example of model construction and assessment for cultured diploid fibroblasts is given.
Kudriavtsev
P S
PS
paul@nevrol.msk.ru
Prokhorov
L Iu
LIu
Khirova
E V
EV
Khokhlov
A N
AN
D000375:Aging / Q000187:drug effects*; D000465:Algorithms; D000818:Animals; D002455:Cell Division / Q000187:drug effects; D002478:Cells, Cultured; D003864:Depression, Chemical; D004353:Drug Evaluation, Preclinical / Q000706:statistics & numerical data; D005347:Fibroblasts / Q000166:cytology / Q000187:drug effects; D008390:Markov Chains; D008954:Models, Biological; D013268:Stimulation, Chemical; D013997:Time Factors