Mechanisms of asthma.
In recent years, our understanding of basic mechanisms of asthma has increased significantly. This article reviews three specific areas that have been the focus of current asthma research: the role of nitric oxide in the control of airway tone and inflammation, mechanisms of exercise-induced asthma, and current studies in the genetics of asthma. Recent advances in each of these areas have contributed to a better understanding of the pathophysiologic mechanisms in asthma and are important in the diagnosis and therapy of this disease.
Teeter
J G
JG
Division of Pulmonary and Critical Care Medicine, University of Maryland School of Medicine, Baltimore 21201, USA.
Bleecker
E R
ER
D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics / Q000503:physiopathology*; D001250:Asthma, Exercise-Induced / Q000503:physiopathology; D001980:Bronchi / Q000503:physiopathology; D016535:Bronchial Hyperreactivity / Q000503:physiopathology; D001991:Bronchitis / Q000503:physiopathology; D006801:Humans; D009569:Nitric Oxide / Q000502:physiology
D009569:Nitric Oxide