title: Adverse effects of transfusions caused by leukocytes.
abstract: The tremendous complexity of blood products gives rise to a range of adverse reactions. Transfusion reactions caused by leukocytes range from subtle and discomforting to dramatic and fatal. Although leukocyte-mediated events usually are harmful, some effects are beneficial. Leukoreduction can prevent most, but not all, adverse reactions. Awareness of the array of leukocyte-mediated transfusion complications and the appropriate preventive and therapeutic measures to be taken is a critical component of sound clinical transfusion practice.
authors.affiliation: Blood Center of Southeastern Wisconsin, USA.
authors.forename: T J
authors.initials: TJ
authors.lastname: Raife
mesh_terms: D001787:Blood Group Incompatibility; D016207:Cytokines / Q000276:immunology / Q000378:metabolism*; D003586:Cytomegalovirus Infections / Q000635:transmission; D005334:Fever / Q000209:etiology; D006086:Graft vs Host Disease / Q000209:etiology; D006680:HLA Antigens / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular; D007962:Leukocytes / Q000276:immunology / Q000378:metabolism*; D065227:Transfusion Reaction
chemical_list: D016207:Cytokines; D006680:HLA Antigens