title: Technetium-99m-tetrofosmin uptake in sarcoidosis stage I.
abstract: The uptake of 99mTc-tetrofosmin in enlarged lymph nodes, of the lung hilus, in the case of sarcoidosis Stage I (histopathologically confirmed by mediastinoscopic biopsy) is demonstrated. On a routine chest radiograph of a 78-yr-old woman, hilar lymphadenopathy was first detected. In the following mammography, disseminated micro calcifications were found in the left breast and a 99mTc-tetrofosmin study was performed for detection of breast cancer. Scintigraphy using 99mTc-tetrofosmin showed clear uptake in the hilar lymph nodes, but not in the left breast. The 99mTc-tetrofosmin uptake in the hilar lymph nodes was due to sarcoidosis confirmed by histology. Therefore, 99mTc-tetrofosmin scintigraphy may be useful in patients with suspected sarcoidosis, especially in Stage I.
authors.affiliation: Department of Nuclear Medicine and Special Endocrinology, Landeskrankenhaus Klagenfurt, Austria.
authors.forename: D
authors.initials: D
authors.lastname: Tschabitscher
authors.forename: H J
authors.initials: HJ
authors.lastname: Gallowitsch
authors.forename: P
authors.initials: P
authors.lastname: Mikosch
authors.forename: E
authors.initials: E
authors.lastname: Kresnik
authors.forename: I
authors.initials: I
authors.lastname: Gomez
authors.forename: M
authors.initials: M
authors.lastname: Molnar
authors.forename: H P
authors.initials: HP
authors.lastname: Dinges
authors.forename: A
authors.initials: A
authors.lastname: Kroiss
authors.forename: P
authors.initials: P
authors.lastname: Lind
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging*; D008482:Mediastinum; D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; D012507:Sarcoidosis / Q000000981:diagnostic imaging*; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C078700:technetium tc-99m tetrofosmin