[Oral contraceptive and risk of disease].
OBJECTIVE
To study the risk and benefits of using compination-type oral contraceptives (COC) for diseases.


METHODS
Meta-analysis was used to estimate the summary relative risk (SRR) for diseases.


RESULTS
The SRR for cardiovascular diseases was > 1 (P < 0.05). The SRR for endometrial cancer and ovarian cancer were < 1 (P < 0.05).


CONCLUSIONS
COC may increase the risk of cardiovascular diseases and may protect from endometrial and ovarian cancer.
Xu
B
B
School of Public Health, Shanghai Medical University.
Xu
Z
Z
D000328:Adult; D002318:Cardiovascular Diseases / Q000139:chemically induced*; D003271:Contraceptive Agents, Female / Q000009:adverse effects*; D016889:Endometrial Neoplasms / Q000139:chemically induced*; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000139:chemically induced*; D012307:Risk Factors
D003271:Contraceptive Agents, Female