title: [Immuno-biological diagnosis of food allergy].
abstract: Food allergy is becoming more frequent, with 6% of asthmatics reporting an isolated food allergy, and 5 to 6% of atopic dermatitis patients also have either a single or multiple true food allergy. There is value in immuno-biological diagnosis by: Measurement of total serum IgE. Measurement of mono-allergen-specific IgE, following a measurement by a multi-allergen of the Trophatope type. A study of elimination of foods for 2 or 3 months followed by their re-introduction. Oral provocation tests in a hospital environment under clinical control and subsequent measurement of the mediators:-Plasma histamine, tryptase, and urinary methylhistamine to give proof of responsibility of the food allergen. Nowadays, it is perfectly possible to include in diagnosis the new technologies of the test of activation of basophils/or lymphocytes by means of flow cytometry.
authors.affiliation: Laboratoire d'Immuno-Allergologie-CHRU, Angers.
authors.forename: A
authors.initials: A
authors.lastname: Sabbah
authors.forename: J
authors.initials: J
authors.lastname: Sainte-Laudy
authors.forename: M
authors.initials: M
authors.lastname: Drouet
authors.forename: M G
authors.initials: MG
authors.lastname: Lauret
authors.forename: M L
authors.initials: ML
authors.lastname: Loiry
authors.forename: M
authors.initials: M
authors.lastname: el Founini
authors.forename: J
authors.initials: J
authors.lastname: Oreac
authors.forename: J
authors.initials: J
authors.lastname: Guitton
authors.forename: M
authors.initials: M
authors.lastname: Doucet
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D000918:Antibody Specificity; D001250:Asthma, Exercise-Induced / Q000209:etiology; D015549:Basophil Degranulation Test; D002648:Child; D002675:Child, Preschool; D017449:Dermatitis, Allergic Contact / Q000150:complications; D004032:Diet; D004531:Eggs / Q000009:adverse effects; D005260:Female; D005512:Food Hypersensitivity / Q000150:complications / Q000175:diagnosis* / Q000178:diet therapy / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood / Q000276:immunology; D008213:Lymphocyte Activation; D008297:Male; D008460:Meat / Q000009:adverse effects; D008875:Middle Aged; D009402:Nephrosis, Lipoid / Q000209:etiology; D012130:Respiratory Hypersensitivity / Q000150:complications; D012882:Skin Tests; D011198:Solanum tuberosum / Q000009:adverse effects; D013552:Swine
chemical_list: D007073:Immunoglobulin E