[Chlorinated carbohydrate content of fetal and pediatric organs and tissues].
Organic halogens are used as pesticides and in chemical industries. They are secreted with breast milk and accumulated in fat tissue of infants. Organic halogens can be found already in newborns. We analysed polychlorinated biphenyl (PCB), DDT, hexachlorocyclohexane (HCH), and heptachlor in subcutaneous fat tissue and other tissues (placenta, liver, kidney, lung, brain, thymus, muscle, heart) of 34 fetuses and dead children. These substances were found regularly in placenta, in fetal subcutaneous fat tissue and in fetal organs. They therefore can influence possibly early and sensitive stages of intrauterine development. The average concentrations found in fetal fat tissue were: PCB 0.7 mg/kg fat tissue, DDT 0.7 mg/kg, HCH 0.14 mg/kg, and heptachlor 0.03 mg/kg.
Bosse
U
U
Zentrum für Kinderheilkunde, Otto-von-Guericke-Universität, Magdeburg.
Bannert
N
N
Niessen
K H
KH
Teufel
M
M
Röse
I
I
D000273:Adipose Tissue / Q000737:chemistry* / Q000378:metabolism; D001921:Brain / Q000378:metabolism; D001923:Brain Chemistry; D002648:Child; D002675:Child, Preschool; D003634:DDT / Q000032:analysis / Q000493:pharmacokinetics; D005333:Fetus / Q000737:chemistry* / Q000378:metabolism; D006533:Heptachlor / Q000032:analysis / Q000493:pharmacokinetics; D001556:Hexachlorocyclohexane / Q000032:analysis / Q000493:pharmacokinetics; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis* / Q000493:pharmacokinetics; D007223:Infant; D007231:Infant, Newborn; D007306:Insecticides / Q000032:analysis* / Q000493:pharmacokinetics; D007668:Kidney / Q000737:chemistry / Q000378:metabolism; D008099:Liver / Q000737:chemistry / Q000378:metabolism; D008168:Lung / Q000737:chemistry / Q000378:metabolism; D009132:Muscles / Q000737:chemistry / Q000378:metabolism; D009206:Myocardium / Q000737:chemistry / Q000378:metabolism; D010920:Placenta / Q000737:chemistry / Q000378:metabolism; D011078:Polychlorinated Biphenyls / Q000032:analysis / Q000493:pharmacokinetics; D013950:Thymus Gland / Q000737:chemistry / Q000378:metabolism; D014018:Tissue Distribution
D006843:Hydrocarbons, Chlorinated; D007306:Insecticides; D001556:Hexachlorocyclohexane; D006533:Heptachlor; D003634:DDT; D011078:Polychlorinated Biphenyls