Mid-dermal elastolysis in an adolescent subsequent to lesions resembling granuloma annulare.
First described by Shelley and Wood in 1977, mid-dermal elastolysis (MDE) is a rare acquired disorder in which there is a bandlike absence of elastic tissue limited to the mid-dermis. In their patient, MDE developed in an area previously involved with recurrent episodes of urticaria. We describe a 15-year-old white girl with well-circumscribed, minimally palpable yellow-white plaques and wrinkling diagnosed histologically as MDE in areas clinically diagnosed 5 years previously as granuloma annulare. As in the first described patient, five years elapsed between clearance of the original skin lesions and the clinical appearance of MDE. To our knowledge, we report the first adolescent case of MDE localized to previous sites of lesions clinically consistent with granuloma annulare and propose that MDE represents an abnormal end-stage reaction to multiple processes.
Yen
A
A
Department of Dermatology, University of Texas Medical Branch, Galveston 77555-0783, USA.
Tschen
J
J
Raimer
S S
SS
D000293:Adolescent; D001284:Atrophy; D001706:Biopsy; D003483:Cutis Laxa / Q000209:etiology* / Q000473:pathology; D004547:Elastic Tissue / Q000473:pathology; D005260:Female; D016460:Granuloma Annulare / Q000150:complications*; D006801:Humans; D012867:Skin / Q000473:pathology*