title: Spatial transformation during 3D reconstruction in positron emission tomography.
abstract: Spatial transformations of positron emission tomographic data for aligning images or transforming to standard anatomical space are usually performed with reconstructed images. However, they can also be performed during the reconstruction process, thereby interpolating the raw data fewer times. We investigated the performance of spatial transformations during reconstruction, implemented it in a standard 3D reconstruction algorithm, and tested it on phantom and patient H215O activation studies for the application of aligning both transmission and emission scans. Performing the transformations during reconstruction was shown to be equivalent to performing the transformations with reconstructed images for this particular application.
authors.affiliation: OD OIR LDRR, Building 10 Room B1N256, 10 Center Drive MSC 1074, Bethesda, MD 20892-1074, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Smith
authors.forename: T
authors.initials: T
authors.lastname: Bruckbauer
authors.forename: K
authors.initials: K
authors.lastname: Wienhard
authors.forename: U
authors.initials: U
authors.lastname: Pietrzyk
authors.forename: L G
authors.initials: LG
authors.lastname: Byars
mesh_terms: D000465:Algorithms; D001834:Body Water / Q000378:metabolism; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000706:statistics & numerical data*; D010104:Oxygen Radioisotopes; D014055:Tomography, Emission-Computed / Q000706:statistics & numerical data*
chemical_list: D010104:Oxygen Radioisotopes