Potent and selective 1,2,3-trisubstituted indole NPY Y-1 antagonists.
Hipskind
P A
PA
Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285, USA. hipskind_philip_a@lilly.com
Lobb
K L
KL
Nixon
J A
JA
Britton
T C
TC
Bruns
R F
RF
Catlow
J
J
Dieckman-McGinty
D K
DK
Gackenheimer
S L
SL
Gitter
B D
BD
Iyengar
S
S
Schober
D A
DA
Simmons
R M
RM
Swanson
S
S
Zarrinmayeh
H
H
Zimmerman
D M
DM
Gehlert
D R
DR
D000818:Animals; D004305:Dose-Response Relationship, Drug; D004435:Eating / Q000187:drug effects; D006801:Humans; D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology*; D051379:Mice; D011869:Radioligand Assay; D017476:Receptors, Neuropeptide Y / Q000037:antagonists & inhibitors* / Q000145:classification / Q000378:metabolism; D013329:Structure-Activity Relationship
D007211:Indoles; D017476:Receptors, Neuropeptide Y; C097212:neuropeptide Y-Y1 receptor