title: [Posterior scleritis in Wegener disease].
abstract: BACKGROUND
  Wegener's granulomatosis is a focal necrotizing granulomatous vasculitis of unknown etiology. It manifests initially as localized inflammation, usually of the lungs, and preceeds to the state of generalisation which can be life-threatening due to renal failure. Ocular and orbital involvement occurs in 28-58% of patients with Wegener's granulomatosis. More often, the anterior segments of the eye are involved whereas inflammation of the posterior segments is quite uncommon.
  
  
  METHODS
  We report a case of posterior scleritis as the initial manifestation of Wegener's granulomatosis in a 65-year-old woman.
  
  
  RESULTS
  Posterior scleritis responded favourably to therapy with systemic steroids and cyclophosphamide.
  
  
  CONCLUSIONS
  Wegener's granulomatosis can have a poor prognosis if not diagnosed and treated in time. Knowledge of posterior scleritis as a possible presenting symptom may therefore facilitate early diagnosis and treatment and prevent progression of the disease.
authors.affiliation: Universitäts-Augenklinik und Poliklinik, Ulm.
authors.forename: A B
authors.initials: AB
authors.lastname: Arnavaz
authors.forename: K
authors.initials: K
authors.lastname: Freissler
authors.forename: G E
authors.initials: GE
authors.lastname: Lang
mesh_terms: D000368:Aged; D005260:Female; D005451:Fluorescein Angiography; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis*; D006801:Humans; D012163:Retinal Detachment / Q000175:diagnosis; D012590:Sclera / Q000473:pathology; D015423:Scleritis / Q000175:diagnosis*