title: Corneal endothelial changes after divide and conquer versus chip and flip phacoemulsification.
abstract: OBJECTIVE
  To evaluate changes in central corneal endothelial cells and corneal thickness after divide and conquer phacoemulsification and chip and flip phacoemulsification.
  
  
  METHODS
  Houston Eye Clinic, Houston, Texas, USA.
  
  
  METHODS
  Forty-four eyes were randomly assigned to one of two groups to have divide and conquer (D/C Group) or chip and flip (C/F Group) phacoemulsification with implantation of a posterior chamber, foldable, silicone intraocular lens performed by one surgeon. Of these, 41 eyes of 37 patients (22 D/C Group, 19 C/F Group) met the inclusion criteria. All surgeries were uneventful. A complete eye examination including specular microscopy and pachymetry was performed preoperatively and 1 week and 1 and 3 months postoperatively.
  
  
  RESULTS
  There were no significant between-group differences in any of the following means: sex; age; time at 70% phaco power; total phacoemulsification time. No correlation was found between ultrasound time and increased corneal thickness except for a significant increase in percentage of hexagonal cells in the C/F Group at 1 month. The only statistically significant between-group differences were greater endothelial cell loss in the C/F Group at 1 month and the percentage change in hexagonal cells at 1 week (1.1% increase, D/C Group; 10.7% decrease, C/F Group).
  
  
  CONCLUSIONS
  The divide and conquer technique led to less endothelial loss and hexagonal cell change than the chip and flip technique, although at 3 months the differences were not significant.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkoknoi, Bangkok, Thailand.
authors.forename: P
authors.initials: P
authors.lastname: Kosrirukvongs
authors.forename: S G
authors.initials: SG
authors.lastname: Slade
authors.forename: R G
authors.initials: RG
authors.lastname: Berkeley
mesh_terms: D000368:Aged; D002452:Cell Count; D048429:Cell Size; D004728:Endothelium, Corneal / Q000473:pathology*; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D008297:Male; D018918:Phacoemulsification / Q000009:adverse effects / Q000379:methods*; D011183:Postoperative Complications / Q000209:etiology / Q000473:pathology*; D011446:Prospective Studies; D012826:Silicone Elastomers
chemical_list: D012826:Silicone Elastomers