title: Altered expression of Fc gammaRIII (CD16) on polymorphonuclear neutrophils from individuals with human immunodeficiency virus type 1 disease and pulmonary tuberculosis.
abstract: Fc gammaRIII (CD16) expression on the surfaces of polymorphonuclear neutrophils was significantly reduced in human immunodeficiency virus type 1-seropositive patients with pulmonary tuberculosis compared to that in individuals with either disease alone or in healthy blood donors. This downregulation of Fc gammaRIII may contribute to the enhanced susceptibility of coinfected individuals to opportunistic infections.
authors.affiliation: National Institute for Virology, and Department of Virology, University of the Witwatersrand, Johannesburg, South Africa.
authors.forename: S
authors.initials: S
authors.lastname: Meddows-Taylor
authors.forename: D J
authors.initials: DJ
authors.lastname: Martin
authors.forename: C T
authors.initials: CT
authors.lastname: Tiemessen
mesh_terms: D015658:HIV Infections / Q000097:blood*; D015497:HIV-1; D006801:Humans; D009169:Mycobacterium tuberculosis; D009504:Neutrophils / Q000378:metabolism* / Q000502:physiology; D017452:Receptors, IgG / Q000097:blood*; D014397:Tuberculosis, Pulmonary / Q000097:blood*
chemical_list: D017452:Receptors, IgG