Probable post-influenza cerebellitis.
The nucleoprotein (NP) gene of type B influenza virus was detected by reverse transcription polymerase chain reaction (RT-PCR) from the cerebrospinal fluid (CSF) of a patient presenting with ataxia due to cerebellitis. The CSF was obtained 7 and 9 weeks after flu syndrome occurred, suggesting persistence of viral genes in the central nervous system (CNS). Although an unusually high serum hemagglutination inhibition (HI) titer against influenza virus B was noted, HI titers of the CSF were not elevated.
Hayase
Y
Y
Department of Virology, Jichi Medical School, Tochigi.
Tobita
K
K
D000328:Adult; D002526:Cerebellar Diseases / Q000134:cerebrospinal fluid / Q000473:pathology / Q000821:virology*; D002555:Cerebrospinal Fluid / Q000821:virology; D017931:DNA Primers / Q000737:chemistry; D004279:DNA, Viral / Q000032:analysis; D004587:Electrophoresis, Agar Gel; D018792:Encephalitis, Viral / Q000134:cerebrospinal fluid / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D009981:Influenza B virus / Q000235:genetics / Q000302:isolation & purification; D007251:Influenza, Human / Q000134:cerebrospinal fluid / Q000209:etiology* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D019590:Nucleocapsid Proteins; D009698:Nucleoproteins; D016133:Polymerase Chain Reaction; D014057:Tomography, X-Ray Computed; D014758:Viral Core Proteins / Q000235:genetics
D017931:DNA Primers; D004279:DNA, Viral; D019590:Nucleocapsid Proteins; D009698:Nucleoproteins; D014758:Viral Core Proteins