title: [Effects of ear acupuncture on beta-adrenoreceptor in lung tissues of guinea-pigs with experimental asthma].
abstract: The maximal binding volume (Bmax) of beta-adrenoreceptor in the lung tissues of guinea-pigs in health group, experimental asthma group and ear acupuncture treatment group was determined with radiological ligand binding analysis. The results were as follows: (1) the Bmax of beta-adrenoreceptor in lung tissues of guinea-pigs in asthma group (52.4 +/- 20.1 fmol/mg protein) was significantly lower than that of healthy group (106.8 +/- 14.0 fmol/mg protein) (P < 0.01); (2) the Bmax in the lung tissues of guinea-pigs in ear acupuncture treatment group (84.5 +/- 35.1 fmol/mg protein) was significantly higher than that of asthma group (P < 0.02), and was similar to that of healthy group(P > 0.05). These suggested it was one of the mechanisms of ear acupuncture treatment on asthma to increase the number of beta-adrenorecepor in the lung tissues.
authors.affiliation: Department of Acupuncture and Moxibustion, PLA General Hospital, Beijing.
authors.forename: L
authors.initials: L
authors.lastname: Chen
authors.forename: X
authors.initials: X
authors.lastname: Liu
authors.forename: X
authors.initials: X
authors.lastname: Wang
authors.forename: G
authors.initials: G
authors.lastname: Yan
authors.forename: X
authors.initials: X
authors.lastname: Hao
authors.forename: L
authors.initials: L
authors.lastname: Wang
authors.forename: Y
authors.initials: Y
authors.lastname: Mu
mesh_terms: D000818:Animals; D001249:Asthma / Q000378:metabolism* / Q000628:therapy; D004431:Ear, External; D015671:Electroacupuncture / Q000379:methods; D006168:Guinea Pigs; D008168:Lung / Q000378:metabolism*; D008297:Male; D011943:Receptors, Adrenergic, beta / Q000378:metabolism*
chemical_list: D011943:Receptors, Adrenergic, beta