Nonlinear property membrane rectifier potassium channel and inhibitory effects of oxygen free radical.
There are at least eight kinds of different potassium channels on cardiac cell membrane. This paper presents a nonlinear property membrane outward current going rectifying potassium channel and the inhibitory effects of oxygen free radical on this channel. The current-voltage relation of this nonlinear-membrane can be defined by an equation I = 8a3/(0.01v2 + 4a2)2 and the maximum conductance of this channel is -75.3 pS.
Bao
G
G
Institute of Basic Medical Sciences, CAMS, Beijing.
Yu
D
D
Liu
Y
Y
Liu
D
D
D000818:Animals; D002648:Child; D002675:Child, Preschool; D005260:Female; D005609:Free Radicals / Q000378:metabolism; D006801:Humans; D008564:Membrane Potentials; D010100:Oxygen / Q000378:metabolism*; D010210:Papillary Muscles / Q000502:physiology*; D015221:Potassium Channels / Q000187:drug effects*; D011247:Pregnancy; D051381:Rats; D017208:Rats, Wistar
D005609:Free Radicals; D015221:Potassium Channels; D010100:Oxygen