Growth hormone deficiency in autoimmune polyglandular syndrome.
We describe a boy with autoimmune adrenal failure and compensated hypothyroidism, associated with isolated growth hormone deficiency (GHD). We suggest an autoimmune mechanism as the underlying etiology for the GHD in this case.
Zung
A
A
Department of Pediatrics, University of Maryland School of Medicine, Baltimore 21201, USA.
Andrews-Murray
G
G
Winqvist
O
O
Chalew
S A
SA
D000293:Adolescent; D000307:Adrenal Gland Diseases / Q000276:immunology; D000324:Adrenocorticotropic Hormone; D001323:Autoantibodies / Q000097:blood; D006063:Chorionic Gonadotropin / Q000627:therapeutic use; D019382:Human Growth Hormone / Q000172:deficiency*; D006801:Humans; D006854:Hydrocortisone / Q000097:blood / Q000627:therapeutic use; D007037:Hypothyroidism / Q000276:immunology; D008297:Male; D016884:Polyendocrinopathies, Autoimmune / Q000150:complications*; D011628:Puberty, Delayed / Q000188:drug therapy / Q000209:etiology; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood / Q000627:therapeutic use
D001323:Autoantibodies; D006063:Chorionic Gonadotropin; D019382:Human Growth Hormone; D000324:Adrenocorticotropic Hormone; D013972:Thyrotropin; D013974:Thyroxine; D006854:Hydrocortisone