title: [Nonsteroidal anti-inflammatory agents: their topical use in the treatment of xerophthalmia secondary to Sjögren's syndrome].
abstract: The authors, in a case-control study, analyzed the topical application of nonsteroidal anti-inflammatory drug (flurbiprofene drops) in patients affected by keratoconjunctivitis sicca in Sjögren's syndrome. The variation of break-up-time values, and xerophthalmia grade were analyzed. A mild increase of mean values of break-up-time (two seconds in the treated group), and a mild decrease of xerophthalmia grade were found.
authors.affiliation: Istituto di Oftalmologia, Università La Sapienza, Roma.
authors.forename: D
authors.initials: D
authors.lastname: Giorgi
authors.forename: A
authors.initials: A
authors.lastname: Giorgi
authors.forename: G
authors.initials: G
authors.lastname: D'Angelo
authors.forename: G
authors.initials: G
authors.lastname: Verrastro
authors.forename: S
authors.initials: S
authors.lastname: Lai
authors.forename: F
authors.initials: F
authors.lastname: Grandinetti
authors.forename: C B
authors.initials: CB
authors.lastname: Gabrieli
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D016022:Case-Control Studies; D004341:Drug Evaluation; D005260:Female; D005480:Flurbiprofen / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000150:complications / Q000188:drug therapy*; D014985:Xerophthalmia / Q000188:drug therapy* / Q000209:etiology
chemical_list: D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D005480:Flurbiprofen