title: [Retrograde ejaculation: a treatable fertility problem].
abstract: Retrograde ejaculation was diagnosed in a 32-year-old man. This condition is an uncommon cause of male infertility. In most cases the only possible treatment is recovery of spermatozoa from the urine followed by artificial insemination; the couple underwent this treatment; the women received intrauterine insemination. In order to ensure the best possible survival of the sperm cells the pH (7.2-8.2) and the osmolality (300-380 mosmol/kg) of the urine were adjusted beforehand by administering bicarbonate and water to the man a few hours before ejaculation. A successful pregnancy ensued. When the couple desired another child the semen quality had deteriorated and in-vitro fertilisation with spermatozoa collected from urine was chosen as a treatment. A second successful pregnancy developed.
authors.affiliation: Academisch Ziekenhuis, afd. Obstetrie en Gynaecologie, Groningen.
authors.forename: J J
authors.initials: JJ
authors.lastname: Dirken
authors.forename: J H
authors.initials: JH
authors.lastname: Cleine
mesh_terms: D000328:Adult; D004542:Ejaculation / Q000187:drug effects / Q000502:physiology*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007099:Imipramine / Q000627:therapeutic use; D007248:Infertility, Male / Q000188:drug therapy / Q000209:etiology / Q000652:urine*; D007317:Insemination, Artificial, Homologous; D008297:Male; D011247:Pregnancy; D013094:Spermatozoa / Q000502:physiology*; D014556:Urine / Q000737:chemistry
chemical_list: D007099:Imipramine