Prognostic factors in leukemia and lymphoma.
The medical literature contains large numbers of reports on the clinical, laboratory, and biologic properties of the leukemias and lymphomas, the clinical relevance of which is largely unknown. This review focuses on the statistical criteria required for the design and interpretation of prognostic factor studies and discusses recent reports regarding potential pretreatment, treatment response, and biologic factors of leukemia and lymphomas that may, on further investigation, have applicability in predicting response to a given therapy.
Smith
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Indiana University School of Medicine, Indianapolis, USA.
D000208:Acute Disease; D003627:Data Interpretation, Statistical; D006801:Humans; D007938:Leukemia / Q000628:therapy*; D007951:Leukemia, Myeloid / Q000628:therapy; D008223:Lymphoma / Q000628:therapy*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000628:therapy; D011379:Prognosis; D012107:Research Design