title: [Prevalence, diagnosis and clinical significance of thrombophilia caused by Va factor resistance to activated C protein].
abstract: Examining 26 patients with early recurrent venous thrombophilias and ischemic attacks revealed that 6 cases had Va factor resistance to activated C protein. The latter suggests that thrombophilia associated with hereditary C- protein resistance is recorded in the Russian population, among the residents of West Siberia in particular.
authors.forename: Z S
authors.initials: ZS
authors.lastname: Barkagan
authors.forename: L P
authors.initials: LP
authors.lastname: Tsyvkina
authors.forename: A N
authors.initials: AN
authors.lastname: Mamaev
authors.forename: I Ia
authors.initials: IIa
authors.lastname: Tseĭmakh
mesh_terms: D000293:Adolescent; D000328:Adult; D001780:Blood Coagulation Tests; D015943:Factor Va / Q000378:metabolism*; D005260:Female; D006801:Humans; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D011486:Protein C / Q000378:metabolism*; D011655:Pulmonary Embolism / Q000209:etiology; D012008:Recurrence; D012426:Russia / Q000453:epidemiology; D012800:Siberia / Q000453:epidemiology; D019851:Thrombophilia / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D013927:Thrombosis / Q000209:etiology
chemical_list: D011486:Protein C; D015943:Factor Va