Coexistence of ganglioglioma and cortical dysplasia in a patient with intractable epilepsy--case report.
An 8-year-old girl presented with coexistence of ganglioglioma and cortical dysplasia manifesting as intractable epilepsy. Preoperative computed tomography demonstrated a small calcified lesion in the left frontal lobe which was not diagnosed as ganglioglioma. Magnetic resonance imaging also failed to demonstrate positive evidence of ganglioglioma or cortical dysplasia. A calcified tumor and the surrounding epileptogenic areas were resected under electrocorticography (ECoG) guidance. Histological examination revealed coexistence of ganglioglioma and cortical dysplasia. The patient became seizure-free after surgery. Resection of the ganglioglioma together with the adjacent epileptogenic area under intraoperative ECoG guidance is important to achieve a successful surgical result in patients with ganglioglioma.
Maehara
T
T
Department of Neurosurgery, Tokyo Metropolitan Neurological Hospital.
Shimizu
H
H
Oda
M
M
Arai
N
N
D001931:Brain Mapping; D001932:Brain Neoplasms / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D002540:Cerebral Cortex / Q000002:abnormalities* / Q000503:physiopathology / Q000601:surgery; D002648:Child; D004292:Dominance, Cerebral / Q000502:physiology; D004569:Electroencephalography; D017029:Epilepsy, Complex Partial / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D004829:Epilepsy, Generalized / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D018303:Ganglioglioma / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D016343:Monitoring, Intraoperative