Helix packing angle preferences.
The distribution of interaxial angles between packed alpha-helices has been explained by a number of elegant models describing how side chains on helices can interdigitate without steric conflicts. Here I show that much of the apparent preference for particular angles is due to statistical bias and that true packing angle preferences are not well described by regular packing models.
Bowie
J U
JU
Department of Chemistry and Biochemistry, University of California, Los Angeles 90095, USA. bowie@mbi.ucla.edu
D008958:Models, Molecular; D015233:Models, Statistical; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry
D011506:Proteins