Jod-Basedow syndrome following oral iodine and radioiodinated-antibody administration.
This is a case of thyrotoxicosis, presumably due to Jod-Basedow syndrome, after stable iodine ingestion for thyroid blockade in a patient with ovarian carcinoma having 131I-labeled monoclonal antibody imaging. With the increased use of radioiodinated antibodies, for therapy and imaging, this possible side effect of excess stable iodine administration should be noted, especially in patients with pre-existing goiter.
El-Shirbiny
A M
AM
Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
Stavrou
S S
SS
Dnistrian
A
A
Sonenberg
M
M
Larson
S M
SM
Divgi
C R
CR
D000368:Aged; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging; D011193:Potassium Iodide / Q000008:administration & dosage / Q000009:adverse effects*; D016719:Radioimmunodetection / Q000009:adverse effects; D013577:Syndrome; D013971:Thyrotoxicosis / Q000139:chemically induced* / Q000000981:diagnostic imaging
D007457:Iodine Radioisotopes; D011193:Potassium Iodide