title: Synthetic and biological catalysts in chemical synthesis: how to assess practical utility.
abstract: Enzymes, synthetic catalysts, and catalytic antibodies can all be used to perform asymmetric reactions, but their practical utility is not always easy to evaluate. Criteria with which to compare such catalysts are proposed and illustrated for asymmetric epoxidation, a reaction to which all three approaches have been applied.
authors.affiliation: Harvard University, Department of Chemistry, Cambridge, MA 02138, USA.
authors.forename: E N
authors.initials: EN
authors.lastname: Jacobsen
authors.forename: N S
authors.initials: NS
authors.lastname: Finney
mesh_terms: D000906:Antibodies / Q000737:chemistry; D002384:Catalysis; D004798:Enzymes / Q000737:chemistry / Q000378:metabolism*; D004852:Epoxy Compounds / Q000737:chemistry
chemical_list: D000906:Antibodies; D004798:Enzymes; D004852:Epoxy Compounds