title: [Effects of intermittent short-course chemotherapy under full-course supervision on the treatment of smear positive pulmonary tuberculosis].
abstract: OBJECTIVE
  To evaluate the effects of intermittent short-course chemotherapy under full-course supervision on the treatment of smear positive pulmonary tuberculosis.
  
  
  METHODS
  The regimens of 2H3R3Z3S3(E3)/4H3R3 and 2H3R3Z3S3E3/6H3R3E3 were respectively used in 125 initial and 249 relapse smear positive pulmonary tuberculosis cases under full-course supervision and management.
  
  
  RESULTS
  The total rate of treatment completion was 99.7%, and the rates of sputum negative conversion in initial and relapse cases were 96.7% and 84.8% respectively. During three-year follow-up, the bacteriological relapse rates were found to be 1.8% in initial cases and 10.2% in relapse cases.
  
  
  CONCLUSIONS
  The regimen was proved to be convenient, economical and effective in tuberculosis control programme.
authors.affiliation: Chengde Antituberculosis Institute.
authors.forename: S
authors.initials: S
authors.lastname: Yan
authors.forename: H
authors.initials: H
authors.lastname: Ye
authors.forename: S
authors.initials: S
authors.lastname: Lin
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage; D011718:Pyrazinamide / Q000008:administration & dosage; D012293:Rifampin / Q000008:administration & dosage; D013307:Streptomycin / Q000008:administration & dosage; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000995:Antitubercular Agents; D011718:Pyrazinamide; D004977:Ethambutol; D007538:Isoniazid; D012293:Rifampin; D013307:Streptomycin