title: Left ventricular geometry in presenting untreated hypertension.
abstract: In order to investigate the spectrum of geometry in our patient population, 63 untreated hypertensives underwent two-dimensional echocardiography. Left ventricular (LV) mass index and relative wall thickness, a measure of wall thickness in relation to cavity size, were calculated from the M-mode strip. In addition, to assess the sphericity of the left ventricle the ratio of LV minor to major hemiaxis was calculated. The subjects comprised 41 men (17 Caucasian, 22 Afro-Caribbean and two Oriental), and 21 women (five Caucasian, 12 Afro-Caribbean and two Oriental). Concentric hypertrophy was present in 46% of subjects, concentric remodelling in 32% of subjects, eccentric hypertrophy in only 6% of subjects and a normal left ventricular shape in 16% of subjects. The degree of sphericity of the left ventricle was similar among the four groups, suggesting that it does not change in uncomplicated hypertension. In contrast to the previously published combined series from Sassari and New York we had a low proportion of patients with either eccentric hypertrophy or normal left ventricular geometry. This is probably due to the high proportion of Afro-Caribbean subjects in our clinic population who are more likely to have left ventricular hypertrophy.
authors.affiliation: Department of Cardiology, Imperial College, St Mary's Hospital, London, UK.
authors.forename: J
authors.initials: J
authors.lastname: Mayet
authors.forename: M
authors.initials: M
authors.lastname: Shahi
authors.forename: N R
authors.initials: NR
authors.lastname: Poulter
authors.forename: P S
authors.initials: PS
authors.lastname: Sever
authors.forename: R A
authors.initials: RA
authors.lastname: Foale
authors.forename: S A
authors.initials: SA
authors.lastname: Thom
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications*; D017379:Hypertrophy, Left Ventricular / Q000209:etiology*; D008297:Male; D008875:Middle Aged