[Topical progesterone as support for the luteal phase in induced cycles].
e efficacy and tolerability of 2.5% natural vaginal progesterone as luteal phase support in pharmacologically induced cycles has been evaluated.


METHODS
On the basis of the administered therapy, the population studied was subdivided at random into four different groups. Sixty patients came to the Sterility Autonomous Department of the Niguarda Ca' Granda Hospital in Milan from November 1994 to January 1996. Both ultrasonographic and plasmatic hormonal parameters have been evaluated on a monthly basis.


RESULTS
The plasma progesterone levels and ultrasonographic endometrial thickness average values resulted more important in groups treated with topical progesterone; in these same groups a greater percentage of pregnancies was observed.


CONCLUSIONS
The results obtained demonstrated that the drug studied can be recommended as a valid luteal phase support in pharmacologically induced cycles.
Zaffaroni
L
L
Sezione Autonoma per la Sterilità e la Patologia Osterica Ginecologica Funzionale, Ospedale Niguarda Ca' Granda, Milano.
Costa
P
P
Vinci
G W
GW
D000287:Administration, Topical; D000328:Adult; D004717:Endometrium / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000188:drug therapy*; D008183:Luteal Phase / Q000187:drug effects*; D010062:Ovulation Induction; D011374:Progesterone / Q000008:administration & dosage* / Q000097:blood / Q000494:pharmacology; D014463:Ultrasonography; D014621:Vagina
D011374:Progesterone