Cytokine signaling: cytokine-inducible signaling inhibitors.
Seven members of a family of cytokine-inducible proteins have been identified, a number of which have been shown to act as negative regulators of cytokine action. All of these proteins contain a central Src homology 2 domain, as well as conserved motifs in their carboxy-terminal regions.
Aman
M J
MJ
Laboratory of Molecular Immunology, National Institute of Health, National Heart, Lung, and Blood Institute, Bethesda, Maryland 20893, USA.
Leonard
W J
WJ
D000595:Amino Acid Sequence; D001665:Binding Sites; D016207:Cytokines / Q000378:metabolism*; D006801:Humans; D017874:Immediate-Early Proteins / Q000737:chemistry / Q000378:metabolism* / Q000502:physiology; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid; D015398:Signal Transduction; D050826:Suppressor of Cytokine Signaling Proteins; D018909:src Homology Domains
D016207:Cytokines; D017874:Immediate-Early Proteins; D050826:Suppressor of Cytokine Signaling Proteins