title: Laboratory evaluation of the I-NOvent nitric oxide delivery device.
abstract: The "I-NOvent delivery system" (Ohmeda Inc., Madison, WI, USA) is a device designed to add nitric oxide to a ventilator breathing system so that the inspired nitric oxide concentration remains constant in spite of changes in minute ventilation. In a laboratory study the device maintained the inspired nitric oxide concentration delivered to a model lung in the range 10.2-10.7 parts per million (ppm) when set to deliver 10 ppm, and in the range 40.5-42 ppm when set to deliver 40 ppm, for tidal volumes of 500, 700 and 900 ml, ventilator rates of 10, 15 and 20 bpm, peak inspiratory flow rates of 30, 40 and 50 litre min-1, and square, sine and decelerating ramp flow waveforms.
authors.affiliation: Department of Anaesthetics, Radcliffe Infirmary, Oxford.
authors.forename: J D
authors.initials: JD
authors.lastname: Young
authors.forename: M
authors.initials: M
authors.lastname: Roberts
authors.forename: L B
authors.initials: LB
authors.lastname: Gale
mesh_terms: D004334:Drug Administration Schedule; D016503:Drug Delivery Systems / Q000295:instrumentation*; D005069:Evaluation Studies as Topic; D006801:Humans; D008163:Luminescent Measurements; D009569:Nitric Oxide / Q000008:administration & dosage*; D013990:Tidal Volume; D012122:Ventilators, Mechanical
chemical_list: D009569:Nitric Oxide