[Host range of influenza viruses and their receptor binding specificities].
Host-range of influenza viruses are established by many factors in nature such as the quantitative, qualitative aspects of the viral receptor, the permissive and non permissive states of host-cell condition, and also the antibody and inhibitor pressure present in the host. Influenza virus hemagglutinin recognizes specific sialyl-sugar chains of the host cell membranes. In this paper, the structure and function of sialyl-sugar chains as influenza virus receptors are described in relation to the variation of influenza viruses and the molecular evolution of influenza virus hemagglutinin.
Suzuki
Y
Y
Department of Biochemistry, University of Shizuoka School of Pharmaceutical Sciences.
D019267:Hemagglutinin Glycoproteins, Influenza Virus / Q000502:physiology; D008958:Models, Molecular; D009975:Orthomyxoviridae / Q000737:chemistry / Q000502:physiology*; D011991:Receptors, Virus / Q000737:chemistry / Q000502:physiology*
D019267:Hemagglutinin Glycoproteins, Influenza Virus; D011991:Receptors, Virus