title: [The mechanisms of action of extracorporeal helium-neon laser irradiation in acute exogenous poisonings].
abstract: Extracorporeal exposure to LG-79 He-Ne laser of 12 mWt power was used in 57 patients hospitalized at the intoxication reanimation department with acute poisonings with psychotropic drugs. The clinical result was a decrease of the incidence of pneumonia in the patients with x-ray signs of venous congestion from 52% among those administered to physiochemotherapy to 24% after this treatment modality. Laser hemotherapy brought about a temporary normalization of the erythrocyte membrane permeability, which was changed biophysically by means of a diffractometer. Red cell aggregation was approximating the norm, decreasing by 20%, and platelet aggregation decreased by 17%. Analysis of the results brought as to a conclusion that He-Ne laser exposure is an effective source of singlet stimulation of molecular O2 evenly dissolved in the blood, which causes resonance oscillations of water difields. This leads to membrane depolarization, which is probably responsible for purification of polarized membranes from toxic agents fixed by them.
authors.forename: I Z
authors.initials: IZ
authors.lastname: Nemtsev
authors.forename: E A
authors.initials: EA
authors.lastname: Luzhnikov
authors.forename: V P
authors.initials: VP
authors.lastname: Lapshin
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Gol'dfarb
authors.forename: A V
authors.initials: AV
authors.lastname: Badalian
mesh_terms: D000208:Acute Disease; D055592:Biophysical Phenomena; D001703:Biophysics; D001769:Blood / Q000528:radiation effects*; D001804:Blood Transfusion, Autologous; D002463:Cell Membrane Permeability / Q000528:radiation effects; D003131:Combined Modality Therapy; D004910:Erythrocyte Membrane / Q000528:radiation effects; D005112:Extracorporeal Circulation; D006801:Humans; D053685:Laser Therapy; D011014:Pneumonia / Q000097:blood / Q000209:etiology / Q000628:therapy; D011041:Poisoning / Q000097:blood / Q000150:complications / Q000628:therapy; D011619:Psychotropic Drugs / Q000506:poisoning*; D011654:Pulmonary Edema / Q000097:blood / Q000209:etiology / Q000628:therapy
chemical_list: D011619:Psychotropic Drugs