[The relationship of C fiber to 5-hydroxytryptamine in spinal cord of rat in electroacupuncture analgesia].
By using spectrofluorophotometry, it was observed that electroacupuntrure at "Huantiao" points of rat could decease the content of 5-hydroxytryptamine (5-HT) and increase the content of 5-hydroxyindoleacetic acid (5-HIAA) in spinal cord. However, the above effects of electroacupunture were obviously reduced after the C fibers of rats had been destroyed by capsaicin, which suggesting that capsaicin-sensitive C fiber might take part in the roles of electroacupuncture's promoting the release and utilization of 5-HT in spinal cord.
Wang
L
L
Department of Physicochemistry, School of Pharmacy, Tongji Medical University, Wuhan.
Li
Z
Z
Guan
X
X
D015667:Acupuncture Analgesia; D000818:Animals; D015671:Electroacupuncture; D005260:Female; D006897:Hydroxyindoleacetic Acid / Q000378:metabolism; D008297:Male; D009412:Nerve Fibers / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012701:Serotonin / Q000378:metabolism*; D013116:Spinal Cord / Q000378:metabolism
D012701:Serotonin; D006897:Hydroxyindoleacetic Acid