title: [Gallbladder cancer in chronic calculous cholecystitis].
abstract: 127 cases of gallbladder cancer are analysed. Among them there were 99(78%) women and 28(22%) men. The majority of the patients were at the age from 61 to 70 years; 19 (15%) patients were younger than 50 years. Mean average age of the patients was 61.7 years. Chronic calculous cholecystitis was detected in 116 (91.3%) patients. In 75 (59%) patients the duration of the disease exceeded 5 years. Women suffer more frequently than men because of higher rate of calculous cholecystitis in women. Radical surgery was possible only in 51 of 97 (52.7%) patients as a result of late diagnosis of the cancer. Cholecystectomy was performed in 32 patients, cholecystectomy in combination with liver resection in 9 patients, tumor removal in borderes of the healthy tissues in 10 patients. Palliative operations were performed in 46 (36.2%) patients. Long-term results of the surgery were followed up in 93 patients. 5 year survival after the radical surgery was 40%, 10 year survival--20%. Mean survival after the palliative surgery was 7 months. Gallbladder cancer is difficult for diagnosis and the results of its treatment are unsatisfactory. Timery surgery of chronic calculous cholecystitis is important in prevention of gallbladder cancer.
authors.affiliation: Department of Liver, Biliary tract and Pancreatic Surgery of NTsKh, Moscow.
authors.forename: A A
authors.initials: AA
authors.lastname: Movchun
authors.forename: G A
authors.initials: GA
authors.lastname: Shatverian
mesh_terms: D000368:Aged; D002763:Cholecystectomy; D002764:Cholecystitis / Q000150:complications* / Q000601:surgery; D002769:Cholelithiasis / Q000150:complications* / Q000601:surgery; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D005706:Gallbladder Neoplasms / Q000150:complications* / Q000401:mortality / Q000601:surgery; D006498:Hepatectomy; D006801:Humans; D008297:Male; D008875:Middle Aged; D015996:Survival Rate; D013997:Time Factors