title: The pulmonary infiltration with eosinophilia syndrome.
abstract: The term eosinophilia denotes an absolute eosinophil count above 500 cells/microL. Eosinophilia has been noted in various inflammatory disorders: skin conditions (eczema, dermatitis, generalized drug reactions), malignancies (Hodgkin's disease and lung cancer), chronic granulomatous disorders (tuberculosis, sarcoidosis), fungal diseases (coccidioidomycosis, aspergillosis), drug- and chemical--related conditions, and idiopathic pulmonary infiltrate and eosinophilia syndromes. The incidence of pulmonary infiltration with eosinophilia is on the rise. Idiopathic pulmonary eosinophilia should be distinguished from the eosinophilic myeloproliferative syndrome. The diagnosis can usually be secured with the help of a good history and physical examination enhanced by simple laboratory tests on blood and sputum and a chest radiogram. The therapy is then directed to correct the initial injury.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, University of Southern California School of Medicine, Los Angeles 90033, USA.
authors.forename: O P
authors.initials: OP
authors.lastname: Sharma
authors.forename: E P
authors.initials: EP
authors.lastname: Bethlem
mesh_terms: D003937:Diagnosis, Differential; D064420:Drug-Related Side Effects and Adverse Reactions; D006099:Granuloma / Q000150:complications; D006801:Humans; D015994:Incidence; D008487:Medical History Taking; D009181:Mycoses / Q000150:complications; D009196:Myeloproliferative Disorders / Q000175:diagnosis; D009369:Neoplasms / Q000150:complications; D010808:Physical Examination; D011657:Pulmonary Eosinophilia / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy; D011859:Radiography; D012871:Skin Diseases / Q000150:complications; D013183:Sputum / Q000737:chemistry