title: [The clinical efficacy in using leukinferon in adults with diseases caused by the varicella-zoster virus].
abstract: To achieve more effective treatment of varicella (chickenpox) and herpes zoster in adults, a wide-spectrum immunocorrective agent containing, together with alpha-interferon, a number of other cytokines of the first phase of immune response was used. In patients with the different severity of disease leukinferon induced a rapid decrease in the severity of the disease, arrested the development of new elements on the skin and the buccal mucosa, and reduced the duration of the fever period. When used in such forms as intramuscular injections in combination with the irrigation of the buccal mucosa and ointment, leukinferon proved to be a highly effective preparation for the treatment of diseases caused by varicella-zoster virus.
authors.forename: V P
authors.initials: VP
authors.lastname: Kuznetsov
authors.forename: I N
authors.initials: IN
authors.lastname: Nikolaeva
authors.forename: G M
authors.initials: GM
authors.lastname: Barer
authors.forename: D L
authors.initials: DL
authors.lastname: Beliaev
authors.forename: A V
authors.initials: AV
authors.lastname: Sundukov
authors.forename: A A
authors.initials: AA
authors.lastname: Babaiants
authors.forename: N D
authors.initials: ND
authors.lastname: Iushchuk
mesh_terms: D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D002644:Chickenpox / Q000628:therapy*; D016207:Cytokines / Q000008:administration & dosage*; D004338:Drug Combinations; D006562:Herpes Zoster / Q000628:therapy*; D006801:Humans; D007273:Injections, Intramuscular; D007370:Interferon Type I / Q000008:administration & dosage*; D009824:Ointments; D012074:Remission Induction; D013997:Time Factors
chemical_list: D000276:Adjuvants, Immunologic; D016207:Cytokines; D004338:Drug Combinations; D007370:Interferon Type I; D009824:Ointments; C062252:leukinferon