title: Understanding enzyme superfamilies. Chemistry As the fundamental determinant in the evolution of new catalytic activities.
authors.affiliation: Department of Pharmaceutical Chemistry, School of Pharmacy, University of California, San Francisco, California 94143-0466, USA.
authors.forename: P C
authors.initials: PC
authors.lastname: Babbitt
authors.forename: J A
authors.initials: JA
authors.lastname: Gerlt
mesh_terms: D000818:Animals; D002384:Catalysis; D019143:Evolution, Molecular; D006801:Humans; D008190:Lyases / Q000737:chemistry* / Q000378:metabolism
chemical_list: D008190:Lyases