[The range of individual sensitivity to adhesion by Neisseria meningitidis serogroup B in young men].
5,340 young adult males, including 5,149 healthy persons, 141 N. meningitidis carriers, 25 patients with generalized meningococcal infection and 6 patients with nasopharyngitis of meningococcal etiology, were examined. The study revealed that red blood cells of 17.4% of healthy persons were highly sensitive to N.meningitidis adhesion (adhesion indices equal to 0.25 and less), red blood cells of 20.4% of persons had low sensitivity to N.meningitidis adhesion (adhesion indices equal to 2 and greater). All other persons with high sensitivity of their red blood cells proved to be patients with meningococcal infection or carriers of N.meningitidis of the same group.
Rumiantsev
S N
SN
Simeshchenko
E P
EP
Pospelov
V F
VF
Tatarnikov
V M
VM
Shabarov
I A
IA
Rogacheva
N M
NM
Urmancheeva
Z I
ZI
Piasetskaia
M F
MF
D018829:Adhesins, Bacterial / Q000494:pharmacology; D000293:Adolescent; D000328:Adult; D001422:Bacterial Adhesion; D002353:Carrier State / Q000382:microbiology; D004912:Erythrocytes / Q000187:drug effects; D006801:Humans; D008297:Male; D008585:Meningitis, Meningococcal / Q000382:microbiology; D008589:Meningococcal Infections / Q000382:microbiology; D009304:Nasopharyngitis / Q000382:microbiology; D009345:Neisseria meningitidis / Q000145:classification / Q000472:pathogenicity*; D012703:Serotyping
D018829:Adhesins, Bacterial