[The effect of lesion of nucleus ventromedialis hypothalami on neurogenesis in adult ring doves].
In the present study the effects of lesion hypothalami ventromedialis nucleus (VMN) of ring dove (Streptopelia Risoria) on neurogenesis regarding the lesion-induced change of distribution of proliferating cells in the lateral ventricular zone (LVZ) and new neurons in the non-ventricular zone (VZ) were studied by using [3H] thymidine-autoradiographic and immunohistochemistry methods. The results showed that such lesion not only induced significant increase of neurogenesis in telencephalon (up to 1.62 times of that of the intact doves), but also altered distribution patterns of the newborn neurons. Many of the new neurons confined in neostriatum medialis and pars caudalis of telencephalon, where the rate of neurogenesis in intact dove is very low. Such kinds of neurogenesis in the birds with brain lesions may be region-dependent and somewhat underlie brain repair and alteration of endocrine function after brain injury.
Zou
M X
MX
Department of Biology, Beijing Normal University.
D000818:Animals; D010856:Columbidae; D008297:Male; D017072:Neostriatum / Q000473:pathology; D009416:Nerve Regeneration; D009474:Neurons; D013687:Telencephalon / Q000473:pathology / Q000502:physiology*; D014697:Ventromedial Hypothalamic Nucleus / Q000502:physiology*