Cellular and molecular mechanisms of oxidants and antioxidants.
This report summarizes the major categories of oxidants and antioxidants. The mechanisms for modulating the most potent antioxidant in plasma, vitamin E, are described. The roles of oxidants and antioxidants in the redox-sensitive signal transduction pathway of NF-kappa B are discussed.
Traber
M G
MG
Department of Molecular and Cell Biology, University of California, Berkeley 94720-3200, USA. mgtraber@uclink4.berkeley.edu
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001692:Biological Transport; D005609:Free Radicals; D006801:Humans; D008074:Lipoproteins / Q000097:blood; D016877:Oxidants / Q000494:pharmacology*; D017382:Reactive Oxygen Species; D015398:Signal Transduction / Q000187:drug effects*; D014810:Vitamin E / Q000493:pharmacokinetics / Q000494:pharmacology
D000975:Antioxidants; D005609:Free Radicals; D008074:Lipoproteins; D016877:Oxidants; D017382:Reactive Oxygen Species; D014810:Vitamin E