title: [Necrotizing sarcoid granulomatosis diagnosed by video thoracoscopic lung biopsy].
abstract: A 28-year-old woman was admitted to our hospital because of chest pain. A chest roentgenogram and a chest computed tomogram revealed many nodular shadows on both sides. Examinations of specimens obtained by and by transbronchial lung biopsy during fiberoptic bronchoscopy were not diagnostic, and therefore video thoracoscopic lung biopsy was done. The lung lesion was characterized by aggregates of epithelioid cell granulomas, along with granulomatous and necrotizing angitis. We therefore diagnosed necrotizing sarcoid granulomatosis, and began to administer prednisolone. The nodular shadows disappeared within four weeks. In this case video thoracoscopic lung biopsy was useful in the diagnosis of necrotizing sarcoid granulomatosis in the lung.
authors.affiliation: First Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Koizumi
authors.forename: S
authors.initials: S
authors.lastname: Hashimoto
authors.forename: S
authors.initials: S
authors.lastname: Yamamura
authors.forename: Y
authors.initials: Y
authors.lastname: Morishita
authors.forename: Y
authors.initials: Y
authors.lastname: Abe
authors.forename: T
authors.initials: T
authors.lastname: Majima
authors.forename: N
authors.initials: N
authors.lastname: Nemoto
authors.forename: N
authors.initials: N
authors.lastname: Kinugawa
authors.forename: Y
authors.initials: Y
authors.lastname: Kawabata
authors.forename: T
authors.initials: T
authors.lastname: Horie
mesh_terms: D000328:Adult; D001706:Biopsy / Q000379:methods; D005260:Female; D015769:Granuloma, Respiratory Tract / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008168:Lung / Q000473:pathology*; D009336:Necrosis; D017565:Sarcoidosis, Pulmonary / Q000175:diagnosis* / Q000473:pathology; D013906:Thoracoscopy; D014743:Videotape Recording