[Lipid peroxidation and the antioxidant saturation of the body during the treatment of patients with cancer of the stomach and large intestine].
Condition was studied of the system lipid peroxidation-antioxidants in 243 patients with carcinoma of the stomach and large intestine and 39 patients with non-malignant diseases. No relationship was found between the studied parameters and age, sex of the oncological patients, location and histological structure of the tumour. During different stages, different dysbalance of components of the system was being formed but there was no strong correlation between content and a particular stage. Three types of functioning of the antioxidants system were identified in oncological patients, such as relative compensation, overstrain and depletion. Postoperative changes in the system were determined by its baseline condition and volume of surgical supplies and involved the overstrain and depletion type adequate and inadequate shifts. Suppuration type complications were more commonly seen amongst those subjects demonstrating the baseline overstrain or depletion of the antioxidant system or where there is an inadequate reaction of the above system to the surgical operation-associated stress.
Ial'chenko
N A
NA
Lagutin
V D
VD
D000975:Antioxidants / Q000032:analysis*; D001782:Blood Donors; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000097:blood* / Q000473:pathology / Q000601:surgery*; D007420:Intestine, Large; D015227:Lipid Peroxidation; D008297:Male; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000097:blood* / Q000473:pathology / Q000601:surgery*
D000975:Antioxidants