title: [Cardioxane in pediatric oncohematology].
abstract: The tolerance of cardioxan (JCRF-187, dexrazoxan), an ethylenediamine tetra-acetic acid analog and a Chiron Company product, administered to pediatric oncohematological patients, is discussed. The drug was used in 37 cases of acute lymphoblastic and non-lymphoblastic leukemia, non-Hodgkin's lymphoma and Hodgkin's disease treated by polychemotherapy including anthracycline antibiotics administration. No untoward side-effects or inhibition of the therapeutic effect were observed.
authors.forename: V I
authors.initials: VI
authors.lastname: Kurmashov
authors.forename: I E
authors.initials: IE
authors.lastname: Gavrilova
authors.forename: S A
authors.initials: SA
authors.lastname: Maiakova
authors.forename: A V
authors.initials: AV
authors.lastname: Popa
authors.forename: O V
authors.initials: OV
authors.lastname: Morozova
authors.forename: L F
authors.initials: LF
authors.lastname: Ivanova
authors.forename: B V
authors.initials: BV
authors.lastname: Kurdiukov
authors.forename: N V
authors.initials: NV
authors.lastname: Gavrikova
authors.forename: V V
authors.initials: VV
authors.lastname: Il'iashenko
authors.forename: M
authors.initials: M
authors.lastname: Terzich
mesh_terms: D000293:Adolescent; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D002317:Cardiovascular Agents / Q000494:pharmacology*; D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D006321:Heart / Q000187:drug effects*; D006801:Humans; D011929:Razoxane / Q000494:pharmacology*; D016896:Treatment Outcome
chemical_list: D000903:Antibiotics, Antineoplastic; D002317:Cardiovascular Agents; D011929:Razoxane