[Effect of L-glutamine on the gut glucose metabolism in severe burned miniswines].
In order to investigate the effect of L-glutamine on gut glucose metabolism, 14 miniswines with 30% TBSA full thickness burns were used in this study. The results showed that: the Nonglutamine group exhibited a decreased gut glucose utilization, and glutamine-group showed a small amount of gut glucose net release (0.11 mumol.min-1.kg-1), and from post burn day 4 on, both groups showed net gut glucose release, but glutamine-group had higher net gut glucoses than that of nonglutamine group (P < 0.01). This result suggests that administration of glutamine decreases gut glucose utilization and increases gut glucose synthesis significantly after severe burns.
Yu
B
B
Institute of Burn Research, Southwestern Hospital, Third Military Medical College, Chongqing.
Wang
S
S
You
Z
Z
D000818:Animals; D002056:Burns / Q000378:metabolism*; D005260:Female; D005947:Glucose / Q000378:metabolism*; D005973:Glutamine / Q000494:pharmacology*; D007413:Intestinal Mucosa / Q000378:metabolism*; D013552:Swine; D013556:Swine, Miniature
D005973:Glutamine; D005947:Glucose