title: Discovering high-affinity ligands for proteins.
authors.affiliation: Abbott Laboratories, Pharmaceutical Discovery Division, Abbott Park, IL 60064, USA.
authors.forename: P J
authors.initials: PJ
authors.lastname: Hajduk
authors.forename: R P
authors.initials: RP
authors.lastname: Meadows
authors.forename: S W
authors.initials: SW
authors.lastname: Fesik
mesh_terms: D002626:Chemistry, Pharmaceutical / Q000379:methods*; D003198:Computer Simulation; D015195:Drug Design; D008024:Ligands; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D011506:Proteins / Q000378:metabolism*; D012995:Solubility; D013329:Structure-Activity Relationship
chemical_list: D008024:Ligands; D011506:Proteins