title: A research agenda for AIDS prevention in the developing world.
abstract: BACKGROUND
  In the developing world, HIV is spreading in many epidemiologic patterns, ranging from slow spread in limited segments of the population to exponential growth to mature epidemics. These differences are superimposed on widely varying cultures and patterns of behavior, creating unique challenges for prevention in each setting. Local prevention research is continually necessary to respond appropriately and effectively to local prevention needs and to best use scarce resources.
  We propose a research agenda for AIDS prevention in the developing world, consisting of three main components: epidemiologic and behavioral surveillance; enhancing local understanding of HIV risk behavior; and testing interventions. We review examples of each. This 'bottom-up' research is contrasted with 'top-down' research conducted in the developing world by scientists from developed countries to answer questions of general interest.
  
  
  RESULTS
  The articles published in this volume exemplify the scope and importance of AIDS prevention research in the developing world. They also show what can be accomplished through international collaboration directed towards meeting local needs.
authors.affiliation: University of California, San Francisco 94105, USA.
authors.forename: N
authors.initials: N
authors.lastname: Hearst
authors.forename: J S
authors.initials: JS
authors.lastname: Mandel
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology / Q000517:prevention & control*; D003906:Developing Countries; D006801:Humans; D012307:Risk Factors; D012309:Risk-Taking