[Cerebral infarction due to stenosis of the bilateral internal carotid artery in Turner's syndrome].
A 43-year-old woman was admitted into our hospital because of aphasia and right hemiparesis. Computed tomographic scan demonstrated border zone infarction in the anterior and middle cerebral artery. Magnetic resonance imaging scans showed the borderline area between the terminal branches of the lenticulostriate arteries and the perforating branches of the middle cerebral artery. Digital subtraction ICA angiogram showed severe narrowing of the distal portion of the right and left ICA. A pattern analysis of ambulatory blood pressure monitoring (ABPM) was carried out in this patient, and it was showed "dipper type". Laboratory data was elevated excretion of pituitary gonadotropines and low estrogen excretion. Chromosome analysis revealed the 45, X/46, XX. She was diagnosed with mosaic type of Turner's syndrome. The cerebrovascular abnormality might be due to congenital hypoplasia of arteries, and declining of blood pressure during sleep was possible significant factors in the pathogenesis of cerebral infarction in this patient.
Miyamoto
T
T
Department of Neurology, Southern Tohoku Research Institute for Neuroscience, Fukushima, Japan.
Tarukawa
Y
Y
Katayama
S
S
Sato
M
M
Shimizu
S
S
Homma
M
M
Watanabe
K
K
Miyamoto
M
M
Hirata
K
K
D000328:Adult; D001037:Aphasia; D002343:Carotid Artery, Internal; D016893:Carotid Stenosis / Q000150:complications*; D002544:Cerebral Infarction / Q000209:etiology* / Q000473:pathology; D005260:Female; D006429:Hemiplegia; D006801:Humans; D014424:Turner Syndrome / Q000150:complications*