title: [Allogeneic peripheral blood stem cell transplantation for multiple myeloma].
abstract: We report here with a 46-year-old man with refractory multiple myeloma receiving allogeneic peripheral blood stem cell transplantation from his HLA-matched brother. The preparative regimen consisted of TBI (12Gy), VP16 (15 mg/kg) and cyclophosphamide (120 mg/kg). GVHD prophylaxis consisted of cyclosporin A and short course of methotrexate. The donor received G-CSF at 10 micrograms/kg/day for 5 consecutive days and underwent leukapheresis on days 5 and 6. The neutrophil recovery to 500/microliter and platelet recovery to 20,000/microliter were day 12 and day 15, respectively. The patient is currently well with no GVHD or graft failure and a complete donor's chimerism.
authors.affiliation: Department of Internal Medicine, Kokura Memorial Hospital.
authors.forename: H
authors.initials: H
authors.lastname: Sawada
authors.forename: A
authors.initials: A
authors.lastname: Wake
authors.forename: Y
authors.initials: Y
authors.lastname: Yamasaki
authors.forename: Y
authors.initials: Y
authors.lastname: Izumi
authors.forename: H
authors.initials: H
authors.lastname: Ohno
authors.forename: K
authors.initials: K
authors.lastname: Nakata
mesh_terms: D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000628:therapy*; D014184:Transplantation, Homologous; D016896:Treatment Outcome