title: Impact of surgery on quality of life in Crohn's disease.
abstract: OBJECTIVE
  Health-related quality of life (HRQOL) status is an important component in assessing the impact of disease and its treatments in patients with chronic disorders. We recently validated a HRQOL questionnaire in French patients with inflammatory bowel disease. The aim of this study was to evaluate prospectively the impact of surgery on HRQOL in patients operated on for Crohn's disease (CD).
  
  
  METHODS
  Twenty-six patients (14 women, 12 men; median age 28.5 yr) undergoing an elective ileocolonic resection for CD were studied. The HRQOL questionnaire comprised a general questionnaire of 36 items (Medical Outcomes Study-Short Form 36), to which was added a sleep module, and a specific questionnaire of 28 items (Rating Form of Inflammatory Bowel Disease Patient Concerns), to which were added three independent items because of their pertinence in the French population. HRQOL was assessed immediately preoperatively and 3 months postoperatively.
  
  
  RESULTS
  HRQOL was improved postoperatively compared with the immediate preoperative status in almost all scales. Patient concerns and worries decreased after surgery. However, ranking was unchanged for the five most intense concerns: having an ostomy bag, having surgery, energy level, uncertainty of the disease, and pain or suffering.
  
  
  CONCLUSIONS
  HRQOL is greatly improved after surgery for CD, and this reassuring message might be delivered to our patients. In addition, the questionnaire showed the ability to detect clinical changes over time. This attests to its potential use in research.
authors.affiliation: Clinique des Maladies de l'Appareil Digestif et de la Nutrition, Hôpital Huriez, CH et U Lille, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Yazdanpanah
authors.forename: O
authors.initials: O
authors.lastname: Klein
authors.forename: L
authors.initials: L
authors.lastname: Gambiez
authors.forename: P
authors.initials: P
authors.lastname: Baron
authors.forename: P
authors.initials: P
authors.lastname: Desreumaux
authors.forename: P
authors.initials: P
authors.lastname: Marquis
authors.forename: A
authors.initials: A
authors.lastname: Cortot
authors.forename: P
authors.initials: P
authors.lastname: Quandalle
authors.forename: J F
authors.initials: JF
authors.lastname: Colombel
mesh_terms: D000328:Adult; D003106:Colon / Q000601:surgery; D003424:Crohn Disease / Q000523:psychology / Q000601:surgery*; D005260:Female; D006801:Humans; D007082:Ileum / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011788:Quality of Life; D011795:Surveys and Questionnaires