title: [Clinical and experimental study of kidney tonics plus whole embryo extract in treatment of renal anemia].
abstract: According to the therapeutic principles, reinforcing Kidney-Qi and nourishing the blood were used in treating renal anemia, Renal Anemia Granule No. I and No. II (RAG I and II) were applied in treating patients of renal anemia, the former was a Yin reinforcing agent and the latter a Yang tonics principally. Thirty patients were treated according to the Syndrome Differentiation of TCM and divided into two groups: (1) The combined group, oral liquid of the whole embryo extract was given additionally. (2) The discombined group, no additional drug was given. Patients after treatment all showed significant improvements in serum erythropoietin and hemoglobin (P < 0.05). Experimental study in animal models also displayed the hemoglobin of treated group increased more than that of control group (P < 0.05), which might be related to the enhancement of hematopoietic function of bone marrow.
authors.affiliation: Renal Division, Renji Hospital, Shanghai Second Medical University.
authors.forename: Q Y
authors.initials: QY
authors.lastname: Zhang
authors.forename: J Y
authors.initials: JY
authors.lastname: Zhang
authors.forename: Q W
authors.initials: QW
authors.lastname: Wu
mesh_terms: D000368:Aged; D000740:Anemia / Q000097:blood / Q000628:therapy*; D000818:Animals; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004622:Embryo, Mammalian; D004921:Erythropoietin / Q000097:blood; D005260:Female; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D051381:Rats; D014020:Tissue Extracts / Q000627:therapeutic use*
chemical_list: D004365:Drugs, Chinese Herbal; D006454:Hemoglobins; D014020:Tissue Extracts; D004921:Erythropoietin