title: Investigation of the effects of 50 Hz magnetic fields on purified human hematopoietic progenitors.
abstract: Epidemiological reports suggest a possible association between exposure to extremely low frequency electromagnetic fields (ELF-EMFs) and the frequency of leukemia in men working in the field of electricity or in children living near power lines. At present, there is no experimental evidence for such an association. In this study we investigated the effects of 50 Hz EMFs (sinusoidal EMF of 10 microT or 1 mT) on human purified hematopoietic progenitor cells which are the first targets of a leukemogenic process. The results failed to reveal any significant changes in cell proliferation, cell kinetics, ultrastructure or clonogenic potential of these progenitors which could be related to a leukemogenic effect.
authors.affiliation: Laboratoire d'Hématologie Cellulaire et Moléculaire, UFR des Sciences Pharmaceutiques et Biologiques, Paris, France.
authors.forename: J
authors.initials: J
authors.lastname: Nafziger
authors.forename: L
authors.initials: L
authors.lastname: Devevey
authors.forename: V
authors.initials: V
authors.lastname: Tricottet
authors.forename: J J
authors.initials: JJ
authors.lastname: Guillosson
authors.forename: G
authors.initials: G
authors.lastname: Averlant
authors.forename: M
authors.initials: M
authors.lastname: Arock
mesh_terms: D000368:Aged; D018952:Antigens, CD34 / Q000502:physiology; D002453:Cell Cycle / Q000502:physiology; D002455:Cell Division / Q000502:physiology; D002478:Cells, Cultured; D004574:Electromagnetic Fields; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000648:ultrastructure; D006801:Humans; D007938:Leukemia / Q000209:etiology; D008875:Middle Aged
chemical_list: D018952:Antigens, CD34