title: Fats in seasoning and the relationship to pancreatic cancer.
abstract: The relationship between consumption of fat in seasoning and the risk of pancreatic cancer has been considered in a case-control study conducted in Italy between 1983 and 1995 on 362 pancreatic cancer cases and 1502 controls in hospital for acute, not neoplastic, non-digestive tract disorders. Subjective scores (low, intermediate, high) for the intake of butter, margarine and oil were used to evaluate the use of fat in seasoning. No material association was observed for butter or margarine. The score for oil (mainly olive oil) intake was inversely related to the risk of pancreatic cancer: the multivariate odds ratios were 0.76 for the intermediate, and 0.60 for the highest score of intake, and the trend in risk was significant. These findings support the hypothesis that (olive) oil may have a comparatively more favourable impact on the risk of pancreatic cancer than other types of seasoning fats.
authors.affiliation: Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy.
authors.forename: C
authors.initials: C
authors.lastname: La Vecchia
authors.forename: E
authors.initials: E
authors.lastname: Negri
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D016022:Case-Control Studies; D016001:Confidence Intervals; D004041:Dietary Fats / Q000009:adverse effects*; D004042:Dietary Fats, Unsaturated / Q000008:administration & dosage; D005260:Female; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D000069463:Olive Oil; D010190:Pancreatic Neoplasms / Q000453:epidemiology* / Q000209:etiology*; D010938:Plant Oils / Q000008:administration & dosage; D012307:Risk Factors; D017678:Sex Distribution; D017365:Spices / Q000009:adverse effects*; D015996:Survival Rate
chemical_list: D004041:Dietary Fats; D004042:Dietary Fats, Unsaturated; D000069463:Olive Oil; D010938:Plant Oils