title: Constrained reconstruction applied to 2-D chemical shift imaging.
abstract: The method of constrained reconstruction, previously applied to magnetic resonance imaging (MRI), is extended to magnetic resonance spectroscopy. This method assumes a model for the MR signal. The model parameters are estimated directly from the phase encoded data. This process obviates the need for the fast Fourier transform (FFT) (which often exhibits limited resolution and ringing artifact). The technique is tested on simulated data, phantom data, and data acquired from human liver in vivo. In each case, constrained reconstruction offers spatial resolution superior to that obtained with the FFT.
authors.affiliation: Center for Devices and Radiological Health, Food and Drug Administration, Rockville, MD 20852 USA. kaw@fdadr.cdrh.fda.gov
authors.forename: K A
authors.initials: KA
authors.lastname: Wear
authors.forename: K J
authors.initials: KJ
authors.lastname: Myers
authors.forename: S S
authors.initials: SS
authors.lastname: Rajan
authors.forename: L W
authors.initials: LW
authors.lastname: Grossman
mesh_terms: D016477:Artifacts; D003198:Computer Simulation; D005583:Fourier Analysis; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008099:Liver / Q000378:metabolism; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy; D008956:Models, Chemical; D018482:Muscle, Skeletal / Q000378:metabolism; D019047:Phantoms, Imaging; D010710:Phosphates / Q000737:chemistry; D010725:Phosphocreatine / Q000378:metabolism; D010759:Phosphorus Isotopes
chemical_list: D010710:Phosphates; D010759:Phosphorus Isotopes; D010725:Phosphocreatine