Appearance of immune complex glomerulonephritis following the onset of type I diabetes mellitus in a child.
Renal disease is a frequent late complication of type I diabetes mellitus, occurring almost entirely in adult patients. Typical diabetic nephropathy is characterized by proteinuria, and by the histological lesions of mesangial expansion and basement membrane thickening. We report an interesting case of a 3-year-old boy who developed immune complex glomerulonephritis with nephrotic syndrome 2 months after the onset of insulin-dependent diabetes mellitus.
Robinson
L A
LA
Department of Pediatric Nephrology, Duke University Medical Center, Durham, NC 27710, USA.
Howell
D N
DN
Wigfall
D R
DR
Foreman
J W
JW
D001706:Biopsy; D002675:Child, Preschool; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000175:diagnosis; D003928:Diabetic Nephropathies / Q000175:diagnosis / Q000209:etiology*; D003937:Diagnosis, Differential; D005921:Glomerulonephritis / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D007105:Immune Complex Diseases / Q000175:diagnosis / Q000209:etiology*; D007668:Kidney / Q000473:pathology; D008297:Male; D009404:Nephrotic Syndrome / Q000175:diagnosis / Q000209:etiology; D013997:Time Factors