title: Multimodality treatment of esophageal disruptions.
abstract: The treatment of esophageal disruptions has changed since 1981. The value of a more selective assessment in six spontaneous ruptures and 30 mostly intrathoracic (83.4%) esophageal perforations is evaluated in this study. Based on the previous state of the esophagus, the time factor, and type and site of the disruption, reinforced primary repair (by diaphragmatic, muscular, pleural flap, or fundoplication), transhiatal closure, resection, intubation, suture combined with myotomy and fundoplication, esophageal diversion, and transhiatal mediastinal drainage were employed. The overall 30-day hospital mortality was 19.4%. Although these operations were mostly used in late (24 h to 7 months) perforations and ruptures, none of the patients with reinforced repair by autogenous diaphragmatic, muscular, or pleural flaps or fundoplication had fatal outcome for breakdown of the closure. Only patients with renal, cardiac, or multiorgan failure as a consequence of sepsis due to time elapsed before hospital admission died. The key to improve the prognosis of this life-threatening emergency is the more appropriate selection of the primary employed procedure.
authors.affiliation: Postgraduate Medical University, Thoracic Surgical Clinic, Budapest, Hungary.
authors.forename: L
authors.initials: L
authors.lastname: Kotsis
authors.forename: S
authors.initials: S
authors.lastname: Kostic
authors.forename: K
authors.initials: K
authors.lastname: Zubovits
mesh_terms: D003131:Combined Modality Therapy; D004935:Esophageal Diseases / Q000209:etiology / Q000401:mortality / Q000628:therapy; D004939:Esophageal Perforation / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D004947:Esophagus / Q000293:injuries; D017052:Hospital Mortality; D006801:Humans; D007441:Intubation, Gastrointestinal; D012189:Retrospective Studies; D012421:Rupture; D012422:Rupture, Spontaneous; D013524:Surgical Flaps; D013536:Suture Techniques; D016896:Treatment Outcome