Members of the AAA-gene family are involved in early embryogenesis of vertebrates.
Here the nucleotide sequence of three cDNAs from Xenopus laevis are reported. The corresponding genes belong to the AAA-family of genes showing the strongest sequence homology to the human HIV-1 Tat binding protein 1 (TBP-1) and to the yeast SUG1 gene, respectively. Analysis of their expression pattern indicate that they are maternally stored in oocytes and involved in very early stages of vertebrate embryogenesis.
Nacken
W
W
Institute of Experimental Dermatology, Münster Medical School, Germany. nacken@uni-muenster.de
D000251:Adenosine Triphosphatases / Q000235:genetics*; D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D018076:DNA, Complementary; D005314:Embryonic and Fetal Development / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D012689:Sequence Homology, Nucleic Acid; D014982:Xenopus laevis / Q000235:genetics
D018076:DNA, Complementary; D000251:Adenosine Triphosphatases