[Effect of electro-acupuncture and transcutaneous electric nerve stimulation on experimental diabetes and its neuropathy].
In this paper, the experimental diabetic rats induced by streptozotocin (STZ, i.p. 50 mg/kg) were divided into three groups, electro-acupuncture (EA group, n = 8), transcutaneous electric nerve stimulation (TENS group, n = 8), at bilateral Shenshu and Zusanli points for 20 minutes once every 2-3 days for five weeks, and without any treatment (DM group, n = 6) respectively. As compared with the DM group, the increased plasma glucose levels was lowered significantly in EA group (P < 0.05) and slightly in TENS group (P > 0.05) by the end of the sixth week. And the symtoms of polyphagia, polydipsia and polyuria were attenuated in EA group. The motor nerve conduction velocity slowing was prevented or corrected after a course of four and six weeks treatment in EA and TENS group respectively. In the DM and TENS groups the pain threshold was lowered at 6-20 days after injection of STZ, but elevated in EA group, their differences were of significance (P < 0.05). In general, the efficiency of EA treatment on experimental diabetes and its neuropathy was better than that of TENS therapy.
Mo
X
X
Institute of Acupuncture and Moxibustion, China Academy of Traditional Chinese Medicine, Beijing.
Chen
D
D
Ji
C
C
Zhang
J
J
Liu
C
C
Zhu
L
L
D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D003921:Diabetes Mellitus, Experimental / Q000628:therapy*; D003929:Diabetic Neuropathies / Q000628:therapy*; D015671:Electroacupuncture; D008297:Male; D017288:Pain Threshold; D051381:Rats; D017208:Rats, Wistar; D004561:Transcutaneous Electric Nerve Stimulation
D001786:Blood Glucose