[Morphological and functional correlations of the protective action of coenzyme A in cisplatin ototoxicity (II)].
Earlier studies have shown that coenzyme A (CoA) protects against cisplatin (CP) induced deafness in guinea pigs. We studied the correlation between the latency of the N1 wave in electrocochleography and total loss of cilia in hair cells by scanning electron microscopy.
Ayala Martínez
L
L
Departamento de ORL, Facultad de Medicina, Universidad de Granada.
Fernández
F
F
Crespo
P V
PV
Campos
A
A
Ciges
M
M
D000818:Animals; D000970:Antineoplastic Agents / Q000009:adverse effects*; D002945:Cisplatin / Q000009:adverse effects*; D003065:Coenzyme A / Q000627:therapeutic use*; D003638:Deafness / Q000139:chemically induced* / Q000517:prevention & control*; D006168:Guinea Pigs; D006198:Hair Cells, Auditory / Q000187:drug effects* / Q000648:ultrastructure; D008854:Microscopy, Electron
D000970:Antineoplastic Agents; D002945:Cisplatin; D003065:Coenzyme A