Protein regulation by phosphatidylinositol lipids.
Phosphatidylinositol lipids are best known as a source of the second messengers inositol trisphosphate and diacylglycerol. Some phosphatidylinositol lipids may directly regulate cytoskeletal events, however. To understand the role of lipids in signaling, help from both synthetic chemists and physical chemists is needed.
Janmey
P A
PA
Brigham and Women's Hospital, Department of Biomedical and Biological Sciences, Harvard Medical School, Boston, MA 02115, USA.
D000818:Animals; D001665:Binding Sites; D003599:Cytoskeleton / Q000378:metabolism; D006801:Humans; D008055:Lipids / Q000502:physiology*; D010716:Phosphatidylinositols / Q000502:physiology*; D014176:Protein Biosynthesis; D018160:Receptors, Cytoplasmic and Nuclear / Q000378:metabolism; D015398:Signal Transduction / Q000502:physiology*
D008055:Lipids; D010716:Phosphatidylinositols; D018160:Receptors, Cytoplasmic and Nuclear; C040985:phosphatidylinositol receptors