Structure and function of the long terminal repeats of feline leukemia viruses derived from naturally occurring acute myeloid leukemias in cats.
Long terminal repeats of feline leukemia viruses cloned from feline acute myeloid leukemias frequently contained direct repeats of 40 to 74 bp in the upstream region of the enhancer (URE). The repetitive URE conferred an enhancer function upon gene expression in myeloid cells, suggesting its association with tumorigenic potential in myeloid cells.
Nishigaki
K
K
Department of Veterinary Internal Medicine, Faculty of Agriculture, University of Tokyo, Japan.
Okuda
M
M
Endo
Y
Y
Watari
T
T
Tsujimoto
H
H
Hasegawa
A
A
D000208:Acute Disease; D000818:Animals; D001483:Base Sequence; D002371:Cat Diseases / Q000821:virology*; D002415:Cats; D002460:Cell Line; D004279:DNA, Viral; D004742:Enhancer Elements, Genetic; D006801:Humans; D019169:Jurkat Cells; D005256:Leukemia Virus, Feline / Q000235:genetics* / Q000302:isolation & purification; D007951:Leukemia, Myeloid / Q000662:veterinary* / Q000821:virology; D008969:Molecular Sequence Data; D012091:Repetitive Sequences, Nucleic Acid; D012689:Sequence Homology, Nucleic Acid; D014158:Transcription, Genetic
D004279:DNA, Viral