[Determination of estrogen receptor and progesterone receptor of the sinonasal malignant neoplasms].
To examine the relationship between sex steroid receptor and sinonasal malignant neoplasms, estrogen receptor (ER) and progesterone receptor (PR) were determined in 25 cases of sinonasal malignant neoplasms, 10 cases of sinonasal papillomas, 31 cases of nasal polyps and 12 cases of normal nasal mucosa. The determination of ER and PR was done by radioligand binding assay of receptors (RBAR). The results indicated that sinonasal malignant neoplasms had higher concentrations of ER and PR binding protein, while sinonasal papillomas, nasal polyps and normal nasal mucosa were found to contain lower concentration of ER and PR, and the differences were significant. (P < 0.01). It is suggested that sinonasal malignant neoplasms might depend on ER and PR.
Li
T
T
First Affilliated Hospital, Sun Yat-Sen University of Medical Sciences, Guangzhou.
Qiu
Q
Q
Wu
N
N
D000293:Adolescent; D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000737:chemistry*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000737:chemistry; D008297:Male; D008875:Middle Aged; D010212:Papilloma / Q000737:chemistry; D010255:Paranasal Sinus Neoplasms / Q000737:chemistry*; D011869:Radioligand Assay; D011960:Receptors, Estrogen / Q000032:analysis*; D011980:Receptors, Progesterone / Q000032:analysis*
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone