title: [Identification of the origin of 7q+ marker chromosome in a mental retard patient].
abstract: The present chromosome-specific and chromosome-band-specific probe pools constructed by the technique of human chromosome microdissection and PCR were taken as painting probes. Using the forward chromosome painting and chromosome screening method, we had identified a chromosome additional fragment of a 7 q+ marker chromosome in a patient originated from 3 q 26-->3 qter, and ascertained the patient's karyotype was 46, XX, -7, + der (7) t (7;3) (7 pter-->7 q 32::3 q 26-->3 qter). Applying this strategy, we can identify the origin of marker chromosomes fastly and effectively.
authors.affiliation: Hunan Medical University, State Key Laboratory of Medical Genetics, Changsha.
authors.forename: J J
authors.initials: JJ
authors.lastname: Fu
authors.forename: J H
authors.initials: JH
authors.lastname: Xia
authors.forename: Z G
authors.initials: ZG
authors.lastname: Long
authors.forename: Y
authors.initials: Y
authors.lastname: Yang
authors.forename: Q
authors.initials: Q
authors.lastname: Pan
authors.forename: X D
authors.initials: XD
authors.lastname: Liao
authors.forename: X
authors.initials: X
authors.lastname: Xia
authors.forename: S X
authors.initials: SX
authors.lastname: Chen
mesh_terms: D002648:Child; D002893:Chromosomes, Human, Pair 3; D002897:Chromosomes, Human, Pair 7; D005260:Female; D006801:Humans; D008607:Intellectual Disability / Q000235:genetics*; D014178:Translocation, Genetic