Bacterial virulence in urinary tract infection.
Urinary tract infections (UTI) are caused by a variety of gram-negative bacteria that ascend into the urinary tract and establish bacteriuria often at levels greater than or equal to 10(5) bacteria/ mL of urine. Escherichia coli dominate as the causative agent in all patient groups, with Staphylococcus saprophyticus as the second most common, accounting for about 10% to 30% of the infections in young adult women depending on the season. This article covers the pathogenesis and inflammatory response of UTI and the virulence factors of uropathogenic E. coli.
Svanborg
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Department of Medical Microbiology, Lund University, Sweden.
Godaly
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D000328:Adult; D002999:Clone Cells; D004926:Escherichia coli / Q000235:genetics / Q000378:metabolism / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000276:immunology / Q000378:metabolism / Q000382:microbiology*; D005260:Female; D006460:Hemolysin Proteins / Q000378:metabolism; D006801:Humans; D006877:Hydroxamic Acids / Q000378:metabolism; D007249:Inflammation / Q000382:microbiology; D008070:Lipopolysaccharides / Q000378:metabolism; D011135:Polysaccharides, Bacterial / Q000378:metabolism; D014552:Urinary Tract Infections / Q000276:immunology / Q000378:metabolism / Q000382:microbiology*; D014774:Virulence
D006460:Hemolysin Proteins; D006877:Hydroxamic Acids; D008070:Lipopolysaccharides; D011135:Polysaccharides, Bacterial; C031819:aerobactin