title: Choroidal hemangiomas: visual and anatomic results of treatment by photocoagulation or radiation therapy.
abstract: OBJECTIVE
  Choroidal hemangioma is a benign hamartoma that causes accumulation of subretinal fluid and resultant visual loss. Although photocoagulation can result in resolution of subretinal fluid, some have found that recurrence is common and final visual acuity often is poor. The purpose of this study is to evaluate the visual and anatomic results of radiation therapy and photocoagulation in treating patients with visual loss from choroidal hemangiomas.
  
  
  METHODS
  A retrospective review was performed of patients with circumscribed choroidal hemangiomas (CCH) or diffuse choroidal hemangiomas (DCH) treated for visual loss caused by accumulation of subretinal fluid. Of 23 patients with CCH, 13 were treated by photocoagulation, 8 by plaque brachytherapy, and 2 by lens-sparing external beam radiation therapy (LSRT). All five patients with DCH were treated by LSRT.
  
  
  RESULTS
  Of patients with CCH treated by brachytherapy, six (75%) of eight had visual acuity of 6/12 or better at 1 year and 8 (100%) of 8 had no subretinal fluid. Of patients with CCH treated by photocoagulation, 5 (38%) of 13 had visual acuity of 6/12 or better at 1 year and 6 (46%) of 13 had no subretinal fluid. Of patients with CCH treated by LSRT, none of two had visual acuity of 6/12 or better at 1 year and one of two had no subretinal fluid. Of the five patients with DCH treated by LSRT, all had complete resolution of subretinal fluid. Two had marked visual improvement and in the other three, vision was stabilized.
  
  
  CONCLUSIONS
  Plaque brachytherapy is an effective alternative to photocoagulation for treatment of subretinal fluid caused by CCH. Lens-sparing external beam radiation therapy is effective treatment in patients with DCH.
authors.affiliation: Department of Ocular Oncology, St. Bartholomew's Hospital, London, England.
authors.forename: S A
authors.initials: SA
authors.lastname: Madreperla
authors.forename: J L
authors.initials: JL
authors.lastname: Hungerford
authors.forename: P N
authors.initials: PN
authors.lastname: Plowman
authors.forename: H C
authors.initials: HC
authors.lastname: Laganowski
authors.forename: P T
authors.initials: PT
authors.lastname: Gregory
mesh_terms: D000293:Adolescent; D000328:Adult; D001918:Brachytherapy; D002830:Choroid Neoplasms / Q000503:physiopathology / Q000628:therapy*; D005122:Exudates and Transudates; D005260:Female; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006391:Hemangioma / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D017075:Laser Coagulation; D008297:Male; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology*
chemical_list: D007457:Iodine Radioisotopes