Factors influencing the photo-reproduction of hydroa vacciniforme lesions.
Hydroa vacciniforme vesicles can be reproduced experimentally with repetitive UVA irradiations, but this photo-reproduction is not constant. The aim of this study was to search for the factors that influence photo-reproduction. To reproduce hydroa vacciniforme lesions six patients underwent repetitive UVA and polychromatic irradiations on the back. In four patients out of six, UVA irradiation with high doses induced papulo-vesicular lesions. Photo-induced lesions were very close to those induced by sunlight. Photo-reproduction failed when phototesting was done after or shortly before remission. Therefore, the absence of photo-reproduction appears to be a good prognostic factor.
Leroy
D
D
Department of Dermatology, Centre Hospitalier Universitaire, Caen, France.
Dompmartin
A
A
Michel
M
M
Tack
B
B
Bravard
P
P
Louvet
S
S
D000293:Adolescent; D000328:Adult; D002648:Child; D002921:Cicatrix / Q000473:pathology; D004890:Erythema / Q000209:etiology / Q000503:physiopathology; D005260:Female; D006801:Humans; D006837:Hydroa Vacciniforme / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D008297:Male; D009336:Necrosis; D011379:Prognosis; D011537:Pruritus / Q000209:etiology; D011829:Radiation Dosage; D012008:Recurrence; D012075:Remission, Spontaneous; D012867:Skin / Q000473:pathology; D012882:Skin Tests / Q000379:methods; D013472:Sunlight / Q000009:adverse effects; D014466:Ultraviolet Rays / Q000009:adverse effects*