title: [Application of gene gun for local-regional cancer].
abstract: We studied the in vivo gene transfusion using a gene gun, formerly used in plants and culture cells. The hand-held type gene gun (Helios Gene Gun System) is simple and convenient for effective gene transfection in living animals. This method has some advantages in that there is no need for use of viral vector, independence on the cell cycle and local inducement of plural genes. There is a great possibility for application to local-regional cancer.
authors.affiliation: Dept. of Clinical Pharmacology, Jichi Medical School.
authors.forename: E
authors.initials: E
authors.lastname: Kobayashi
authors.forename: Y
authors.initials: Y
authors.lastname: Yoshida
authors.forename: A
authors.initials: A
authors.lastname: Fujimura
authors.forename: T
authors.initials: T
authors.lastname: Yamanaka
authors.forename: H
authors.initials: H
authors.lastname: Endo
authors.forename: T
authors.initials: T
authors.lastname: Hamamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Kagawa
mesh_terms: D000818:Animals; D019470:Biolistics / Q000295:instrumentation*; D004247:DNA / Q000008:administration & dosage; D008114:Liver Neoplasms, Experimental / Q000628:therapy*; D008297:Male; D051381:Rats; D017208:Rats, Wistar
chemical_list: D004247:DNA