title: Metastasis of breast carcinoma to eyelid and orbit of a postmenopausal woman: good response to tamoxifen therapy.
abstract: We report a case of metastatic eyelid and orbital carcinoma in a postmenopausal woman 8 years after mastectomy for cancer. MRI scan T1-weighted images with fat suppression revealed an intraconal lesion surrounding the left optic nerve in addition to the left lid tumor. Excision biopsy demonstrated tumor cells in an Indian file pattern. We diagnosed metastasis of breast carcinoma to the eyelid and orbit. Therapy with tamoxifen reduced eyelid and orbital metastases of carcinoma of the breast. Metastatic breast carcinoma should be listed as one of the causes of lesions of the eyelids.
authors.affiliation: Department of Ophthalmology, Nagasaki University School of Medicine, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Saitoh
authors.forename: T
authors.initials: T
authors.lastname: Amemiya
authors.forename: N
authors.initials: N
authors.lastname: Tsuda
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary*; D000284:Administration, Oral; D000368:Aged; D001706:Biopsy; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D004965:Estrogen Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D005142:Eyelid Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D015409:Mastectomy, Radical; D009918:Orbital Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000556:secondary*; D017698:Postmenopause; D013629:Tamoxifen / Q000008:administration & dosage / Q000627:therapeutic use*; D014792:Visual Acuity; D014794:Visual Fields
chemical_list: D004965:Estrogen Antagonists; D013629:Tamoxifen