Emerging treatments in multiple sclerosis.
Currently used and developing therapies for multiple sclerosis (MS) are dealing with the treatment of acute exacerbations, the prevention of relapses and of the progression of neurological handicap, the treatment of symptoms, and the repair of demyelinated lesions. New insights into the treatment of acute relapses as well as recent immunomodulatory and immunosuppressive agents tested in MS are exposed in this brief review. Interferon-beta (1a and 1b), copolymer 1 and new immunosuppressive therapies are particularly discussed with emphasis on their potential to alter the course of MS.
Schluep
M
M
Service de Neurologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Suisse. Myriam.Schluep@chuv.hospvd.ch
Bogousslavsky
J
J
D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D018450:Disease Progression; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016899:Interferon-beta / Q000627:therapeutic use; D009103:Multiple Sclerosis / Q000628:therapy*; D010166:Palliative Care / Q000639:trends; D055502:Secondary Prevention; D013256:Steroids / Q000627:therapeutic use
D000276:Adjuvants, Immunologic; D007166:Immunosuppressive Agents; D013256:Steroids; D016899:Interferon-beta