A novel quantitative measure of Tracé-alternant EEG activity and its association with sleep states of preterm infants.
This study describes the application of a novel quantitative method for classifying patterns of EEG activity that are associated with the predominant sleep-states of newborn infants. Periods in which there are bursts of high-voltage slow wave activity in the EEG that alternate with periods of low-voltage activity are termed Tracé-alternant. During active or REM sleep. Tracé-alternant is absent and EEG activity is characterized by a variable mixture of frequencies including intermittent high frequency (10-20 Hz) activity superimposed on slower frequencies. Results show that an analytic method previously developed in fetal baboons for identifying EEG segments with and without Tracé-alternant successfully distinguishes homologous patterns of EEG activity in preterm infants. This method provides an excellent objective approach for monitoring changes in EEG patterns that are coincident with behaviorally defined sleep states.
Myers
M M
MM
Division of Developmental Psychobiology, New York State Psychiatric Institute, New York 10032, USA.
Fifer
W P
WP
Grose-Fifer
J
J
Sahni
R
R
Stark
R I
RI
Schulze
K F
KF
D000818:Animals; D002540:Cerebral Cortex / Q000502:physiology; D004569:Electroencephalography / Q000145:classification / Q000295:instrumentation*; D005583:Fourier Analysis; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D010215:Papio / Q000196:embryology; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*; D012894:Sleep Stages / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology; D013045:Species Specificity