title: Laparoscopic Nissen fundoplication in children under 2 years of age.
abstract: BACKGROUND
  Antireflux operations have been recommended for infants and children suffering from complications related to gastroesophageal reflux (GER). In recent years, the laparoscopic approach has been used increasingly for antireflux surgery in adult patients. This is our initial experience with Nissen fundoplication in infants and children under 2 years of age.
  
  
  METHODS
  We operated on 11 patients weighing between 3.0 and 10.0 kg. The main indications for surgery were GER-induced aspiration pneumonia and failure to thrive, in spite of intensive conservative treatment. All patients except one had an associated neurological abnormality, including six patients with familial dysautonomia.
  
  
  RESULTS
  All attempted operations were completed successfully laparoscopically, with only a few postoperative complications and acceptable short-term results. The clinical considerations and technical aspects unique to this specific group of patients are discussed.
  
  
  CONCLUSIONS
  Laparoscopic Nissen fundoplication is feasible, safe, and effective, even in very small babies.
authors.affiliation: Department of Surgery and Pediatric Surgery, Hadassah University Hospital Mount Scopus, and the Hebrew University-Hadassah Medical School, Jerusalem, 91240 Israel.
authors.forename: O
authors.initials: O
authors.lastname: Zamir
authors.forename: R
authors.initials: R
authors.lastname: Udassin
authors.forename: D
authors.initials: D
authors.lastname: Seror
authors.forename: A
authors.initials: A
authors.lastname: Vromen
authors.forename: H R
authors.initials: HR
authors.lastname: Freund
mesh_terms: D000367:Age Factors; D001062:Appendectomy; D001835:Body Weight; D002547:Cerebral Palsy / Q000150:complications; D002675:Child, Preschool; D004402:Dysautonomia, Familial / Q000150:complications; D004750:Enteral Nutrition; D005183:Failure to Thrive / Q000209:etiology / Q000601:surgery; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D018662:Fundoplication / Q000009:adverse effects / Q000379:methods*; D005764:Gastroesophageal Reflux / Q000150:complications / Q000601:surgery; D005774:Gastrostomy; D006760:Hospitalization; D006801:Humans; D007223:Infant; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods; D007902:Length of Stay; D008297:Male; D011015:Pneumonia, Aspiration / Q000209:etiology / Q000601:surgery; D011183:Postoperative Complications; D012449:Safety; D016896:Treatment Outcome