Studies on the ossification of compound transplantation of porous TCP ceramics and bone marrow.
Following the culture of human red marrow with porous TCP ceramics in vitro, a large amount culturing marrow cells adhered well to the surface and inner wall of TCP ceramics and spread well over the dish bottom 4 weeks after cultivation. After the compound transplantation of porous TCP ceramics with red marrow into quadriceps femoris muscle of rabbits, a huge amount of new bone and marrow formed in these sites on and in the ceramics 4 weeks after transplantation. These results showed an excellent biocompatibility between TCP ceramics and marrow and an excellent osteogenic effect in the compound transplantation. The mechanism of ossification and clinical significance about the compound transplantation were discussed.
Zheng
Q
Q
Department of Orthopedics, Xiehe Hospital, Tongji Medical University, Wuhan.
Zhu
T
T
Du
J
J
Wang
H
H
Li
S
S
D000818:Animals; D001854:Bone Marrow Cells / Q000473:pathology; D016026:Bone Marrow Transplantation / Q000379:methods; D018786:Bone Substitutes; D002130:Calcium Phosphates; D002478:Cells, Cultured; D005260:Female; D006801:Humans; D008297:Male; D016348:Osseointegration; D019736:Prostheses and Implants; D011817:Rabbits
D018786:Bone Substitutes; D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous