Cell cycle: checkpoint proteins and kinetochores.
Vertebrate homologs of yeast spindle assembly checkpoint proteins are localized to kinetochores and may act as a sensor for proper chromosome attachment to the mitotic spindle.
Straight
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Department of Physiology, School of Medicine, University of California, San Francisco 94143-0444, USA. straight@cgl.ucsf.edu
D000818:Animals; D002135:Calcium-Binding Proteins / Q000378:metabolism*; D002352:Carrier Proteins; D002453:Cell Cycle; D018797:Cell Cycle Proteins; D005656:Fungal Proteins / Q000378:metabolism*; D006801:Humans; D018386:Kinetochores / Q000378:metabolism*; D009687:Nuclear Proteins; D011494:Protein Kinases / Q000378:metabolism*; D017346:Protein Serine-Threonine Kinases; D015398:Signal Transduction; D008941:Spindle Apparatus / Q000378:metabolism*
D002135:Calcium-Binding Proteins; D002352:Carrier Proteins; D018797:Cell Cycle Proteins; D005656:Fungal Proteins; D009687:Nuclear Proteins; D011494:Protein Kinases; C090464:Bub1 spindle checkpoint protein; D017346:Protein Serine-Threonine Kinases