[Nervous system lymphoma in HIV infection].
Primary CNS lymphoma is recognized as one of the criteria of AIDS. The incidence is 0.4 to 0.56% of AIDS complications. Non-Hodgkin's lymphomas appear as multicentric tumours, mostly located in the hemispheres; they have a B phenotype and have a high grade of malignancy. They are sometimes associated with opportunistic infections. Survival is around 4 to 5 months. The presence of EBV in these tumours is an argument to propose a synergistic role of this virus in the pathogenesis of these tumours. Secondary lymphomas are observed in 40 to 47% of these tumours and must be systematically looked for. Hodgkin's disease is rare. It is mostly diagnosed as secondary compressive epidural tumors.
Mikol
J
J
Service d'Anatomie et Cytologie Pathologies, Hôpital Lariboisière, Paris, France.
Polivka
M
M
Gyuris
A
A
Minarovits
J
J
Morinet
F
F
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D016543:Central Nervous System Neoplasms / Q000150:complications / Q000209:etiology / Q000473:pathology*; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D016483:Lymphoma, AIDS-Related / Q000150:complications / Q000209:etiology / Q000473:pathology*