[New data on the role of glycoproteins in germ cell chemotactism in chick embryo].
Using peroxidase-coupled Concanavalin A during the organogenesis of embryonic gonads, we show that there is a positive correlation between the expression of specific glycoprotein complexes by germ cells and the migratory activity of these cells. An experimental artifice enabled us to subject 'sedentary' primary gonocytes in the undifferentiated gonad to the attractive influence of a young germinal epithelium. Under these conditions, chemotactism was reactivated in the primary gonocytes, in conjunction with a stimulation of their expression of glycosylated complexes.
Cuminge
D
D
Institut d'embryologie cellulaire et moléculaire, CNRS, Nogent-sur-Marne, France.
Dubois
R
R
D000818:Animals; D015415:Biomarkers; D002633:Chemotaxis / Q000502:physiology*; D002642:Chick Embryo; D003208:Concanavalin A / Q000378:metabolism; D005854:Germ Cells / Q000502:physiology*; D006023:Glycoproteins / Q000502:physiology*; D006735:Horseradish Peroxidase / Q000378:metabolism
D015415:Biomarkers; D006023:Glycoproteins; C045779:concanavalin A-horseradish peroxidase conjugate; D003208:Concanavalin A; D006735:Horseradish Peroxidase