Identification of a new DRB3*02 allele (DRB3*0207) by sequence-based typing.
A new DRB3*02 allele (DRB3*0207) was detected in a female Luxembourg Caucasian blood donor by sequence-based typing. The new allele differs from DRB3*0202 by two substitutions in codon 57 resulting in an amino acid change from a charged aspartic acid to a neutral valine. This is the first example of a DRB3 allele pair differing only at codon 57.
Voorter
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CE
Tissue Typing Laboratory, University Hospital Maastricht, The Netherlands.
Hentges
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van den Berg-Loonen
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EM
D000483:Alleles; D001483:Base Sequence; D005260:Female; D006681:HLA-D Antigens / Q000235:genetics*; D059826:HLA-DRB3 Chains; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D044465:White People
D006681:HLA-D Antigens; D059826:HLA-DRB3 Chains