title: [Clinical and experimental study on wenchangning oral liquor in treating infantile autumn diarrhea].
abstract: Gold-Dampness Syndrome of Infantile Autumn diarrhea treated with Wenchangning Oral Liquor was observed clinically. There were 238 cases in the treated group, the cure rate was 81.9%. In comparing with control group (32 cases in Huoxiang Zhengqi Liquid group, 50 cases in gentamycin group), there were highly significant difference between treated and control groups in the cure rate, markedly effective rate, total effective rate, time for stopping diarrhea and for disappearing of clinical symptoms, P < 0.01 and < 0.001. Clinical practice and animal experiments revealed that the drug had no toxic and side-effects. The possible therapeutic mechanisms were; (1) Anti-Rotavirus, anti-diarrhea; (2) Promote the recovery of intestinal digestive and absorptive function; (3) Enhance the immune function of the body; (4) Inhibit the motility of intestinal tract, Wenchangning Oral Liquor is rapid in action, conveniant in administration and safe, conforming to the criteria for the preventing and treating diarrhea of World Health Organization.
authors.affiliation: Baoji TCM Hospital, Shaanxi.
authors.forename: W D
authors.initials: WD
authors.lastname: Zhang
authors.forename: Q S
authors.initials: QS
authors.lastname: Zhou
authors.forename: Z L
authors.initials: ZL
authors.lastname: Yang
mesh_terms: D000818:Animals; D002648:Child; D002675:Child, Preschool; D003968:Diarrhea, Infantile / Q000188:drug therapy* / Q000276:immunology / Q000503:physiopathology; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use* / Q000633:toxicity; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects*; D006801:Humans; D007223:Infant; D017737:Macrophages, Peritoneal / Q000276:immunology; D008297:Male; D051379:Mice; D010587:Phagocytosis / Q000187:drug effects; D051381:Rats
chemical_list: D004365:Drugs, Chinese Herbal