title: [Hepatic arterial chemotherapy for liver cancer over a period of 8 years].
abstract: Hepatic arterial chemotherapy was performed for 27 patients with primary (3), metastatic liver cancer (21), and 3 other cases, over a period of 8 years. Chemotherapy was performed by intermittent hepatic arterial infusion of 5-FU or FAM (in case of metastatic tumor from colorectal cancer), FAM (from gastric cancer), and CDDP or Farmorubicin (HCC). Hepatic resection was performed in 10 cases of metastatic tumor from colorectal cancer, and 8 cases of 10 were curative operation. The 5-year survival rates of curative liver resection group, and non-curative liver resection or non-resection group were 57.1% and 12.5%, respectively. As is the case with metastatic cancer from gastric cancer, pancreatic cancer, and hepatocellular carcinoma (HCC), the prognosis was poor except for one CR case of HCC. We concluded that hepatic arterial chemotherapy may be recommended for a curative resected case of liver metastasis from colorectal cancer.
authors.affiliation: Dept. of Surgery, Sakai Municipal Hospital.
authors.forename: S
authors.initials: S
authors.lastname: Masutani
authors.forename: M
authors.initials: M
authors.lastname: Tatsuta
authors.forename: T
authors.initials: T
authors.lastname: Kawasaki
authors.forename: O
authors.initials: O
authors.lastname: Morimoto
authors.forename: Y
authors.initials: Y
authors.lastname: Tsuji
authors.forename: K
authors.initials: K
authors.lastname: Shiozaki
authors.forename: S
authors.initials: S
authors.lastname: Baba
authors.forename: A
authors.initials: A
authors.lastname: Miya
authors.forename: H
authors.initials: H
authors.lastname: Ishida
authors.forename: T
authors.initials: T
authors.lastname: Satomi
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002945:Cisplatin / Q000008:administration & dosage; D015179:Colorectal Neoplasms / Q000473:pathology; D015251:Epirubicin / Q000008:administration & dosage; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000556:secondary; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000401:mortality; D015996:Survival Rate
chemical_list: D015251:Epirubicin; D016685:Mitomycin; D002945:Cisplatin; D005472:Fluorouracil