title: Comparison of space-maintaining capabilities of Healon and Healon GV during phacoemulsification.
abstract: OBJECTIVE
  To determine whether Healon GV or Healon (both sodium hyaluronate products) maintains space better during phacoemulsification with intraocular lens (IOL) implantation.
  
  
  METHODS
  Department of Ophthalmology, Friedrich-Schiller-University of Jena, Germany.
  
  
  METHODS
  This double-blind, randomized clinical trial comprised 60 patients (30 Healon GV, 30 Healon) eligible for cataract surgery. Patients were evaluated 6 and 24 hours and 5 days postoperatively. A digital slide gauge mounted on an operating microscope was used to measure the distance between the iris and epithelial side of the cornea before surgery and before and after capsulorhexis. The distance between the anterior and posterior lens capsules (i.e., space in the capsular bag) was also measured before and after IOL insertion. The surgeon's objective opinion of the products was evaluated.
  
  
  RESULTS
  The mean anterior chamber depth after capsulorhexis was significantly greater in the Healon GV than in the Healon group (P = .003). The mean distance between the anterior and the posterior lens capsules was significantly larger in the Healon GV than in the Healon group before and after IOL insertion. The subjective evaluation of space-maintaining capacity during surgery also favored Healon GV. Healon was considered easier to inject and remove from the eye.
  
  
  CONCLUSIONS
  Healon GV had better space-maintaining capacity than Healon during cataract surgery with phacoemulsification and IOL insertion.
authors.affiliation: Department of Ophthalmology, University of Jena, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Strobel
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000033:anatomy & histology*; D004311:Double-Blind Method; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage* / Q000737:chemistry; D007903:Lens Capsule, Crystalline / Q000601:surgery; D019654:Lens Implantation, Intraocular; D008970:Molecular Weight; D018918:Phacoemulsification
chemical_list: D006820:Hyaluronic Acid