Human parvovirus B19 infection.
Human parvovirus B19 shows remarkable tropism for human erythroid progenitor cells. The pathogenesis of disease resulting from infection is a dynamic between the viral suppression of erythropoiesis and the host's ability to mount an effective immune response. Understanding this process has led to strategies for treating chronic anemia in persistently infected patients and may result in the development of a vaccine to prevent infection.
Carper
E
E
Avigen, Inc., Alameda, CA 94502, USA.
Kurtzman
G J
GJ
D000740:Anemia / Q000821:virology; D015672:Erythroid Precursor Cells / Q000821:virology; D005315:Fetal Diseases / Q000821:virology; D006801:Humans; D016867:Immunocompromised Host; D010322:Parvoviridae Infections / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy / Q000635:transmission / Q000821:virology*; D016732:Parvovirus B19, Human / Q000145:classification / Q000235:genetics / Q000502:physiology