[Effect of atropine on the enhancing action of Fructus Aurantii Immaturus on the myoelectric activity of small intestine in dogs].
Effect of Fructus Aurantii Immaturus (FAI) was observed by using the computerized electrophysiologic method with the interdigestive myoelectric complex (IDMEC) as criterion. 100% FAI was given to the healthy, awakened and fasting dogs by gastrogavage and as soon as the effect on electric activity of small intestine appeared, atropine was injected. Results showed that the enhancing effect of FAI could be inhibited significantly by atropine, an antagonist of cholinergic receptor. It revealed that although the duration of phase II and general cycle were prolonged, but the spike burst per cluster in the duration between phase II and phase III as well as that per minute were decreased. It suggested the effect of FAI might be relevant with muscarinic receptor.
Huang
Z H
ZH
Department of Physiology, Nanjing Railway Medical College.
Yang
D Z
DZ
Wei
Y Q
YQ
D000818:Animals; D001285:Atropine / Q000494:pharmacology*; D004285:Dogs; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D005260:Female; D007421:Intestine, Small / Q000502:physiology; D018727:Muscarinic Antagonists / Q000494:pharmacology*; D016065:Myoelectric Complex, Migrating / Q000187:drug effects*
D004365:Drugs, Chinese Herbal; D018727:Muscarinic Antagonists; D001285:Atropine