Evaluation and treatment of speech and swallowing disorders associated with myopathies.
Dysphagia, or disordered swallowing, can be demonstrated at any time over the course of many myopathies. Ability to swallow may be impaired because of weakness, inflammation, or dysfunction of the oropharyngeal, laryngeal, and esophageal musculature. Dysphagia may occur during the progression of disease regardless of whether the patient is properly treated. The presentation of signs of dysphagia can vary among patients because of differing patterns of weakness or incoordination of the facial muscles, lips, tongue, palate, pharyngeal constrictors, or smooth and striated muscles of the esophagus. Although the literature has focused on problems in the esophagus, scant attention has been paid to the oropharynx, which is often equally affected. Studies suggest that surgical myotomy and botulinum toxin injection may provide benefits for some patients with esophageal dysfunction. Although the condition is pervasive, there is little information on the incidence of dysphagia in muscular disorders. Because a major complication of dysphagia is aspiration, any sign of swallowing impairment demands medical attention and treatment.
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Department of Rehabilitation Medicine, W. G. Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892, USA.
D003680:Deglutition Disorders / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D006801:Humans; D009135:Muscular Diseases / Q000150:complications*; D013064:Speech Disorders / Q000175:diagnosis* / Q000628:therapy*