Neuropsychological deficits in HIV-1 seropositive and seronegative intravenous drug users (IVDUs): a follow-up study.
Human immunodeficiency virus type 1 (HIV-1) seropositive AIDS free and HIV-1 seronegative intravenous drug users were tested twice with a comprehensive neuropsychological test battery. Only minor group differences were found. Memory difficulties were the most pronounced difference with lower scores in the HIV-1 seropositive group. The memory difficulties were to some degree associated with emotional difficulties, that is, anxiety. The HIV-1 seropositive subjects were tested a third time and there was no further decline in any test with memory content at this testing. The only test that showed a significant decline in the HIV-1 seropositive group was the Trail Making Test.
Hestad
K
K
Department of Biological and Medical Psychology, University of Bergen, Norway.
Aukrust
P
P
Ellertsen
B
B
Kløve
H
H
D015526:AIDS Dementia Complex / Q000175:diagnosis* / Q000523:psychology; D000328:Adult; D001143:Arousal; D005260:Female; D005500:Follow-Up Studies; D018023:HIV Seronegativity; D006679:HIV Seropositivity / Q000175:diagnosis* / Q000523:psychology; D015497:HIV-1; D006801:Humans; D008297:Male; D011939:Mental Recall; D009483:Neuropsychological Tests; D015819:Substance Abuse, Intravenous / Q000523:psychology*