Bioavailability of selenium from veal, chicken, beef, pork, lamb, flounder, tuna, selenomethionine, and sodium selenite assessed in selenium-deficient rats.
The bioavailability of selenium (Se) from veal, chicken, beef, pork, lamb, flounder, tuna, selenomethionine (SeMet), and sodium selenite was assessed in Se-deficient Fischer-344 rats. Se as veal, chicken, beef, pork, lamb, flounder, tuna, SeMet, and sodium selenite was added to torula yeast (TY) basal diets to comprise Se-inadequate (0.05 mg Se/kg) diets. Se as sodium selenite was added to a TY basal diet to comprise a Se-adequate (0.10 mg Se/kg), Se-control diet. The experimental diets were fed to weanling Fischer-344 rats that had been subjected to dietary Se depletion for 6 wk. After 9 wk of the dietary Se repletion, relative activity of liver glutathione peroxidase (GSHPx) from the different dietary groups compared with control rats (100%) was: flounder 106%, tuna 101%, pork 86%, sodium selenite 81%, SeMet 80%, beef 80%, chicken 77%, veal 77%, and lamb 58%. Se from flounder was the most efficient at restoring Se concentrations in the liver and skeletal muscle. Se from sodium selenite, SeMet, beef, veal, chicken, pork, lamb, and tuna was not dietarily sufficient to restore liver and muscle Se after 9 wk of recovery following a 6-wk period of Se depletion.
Wen
H Y
HY
Texas Tech University, Lubbock 79409, USA.
Davis
R L
RL
Shi
B
B
Chen
J J
JJ
Chen
L
L
Boylan
M
M
Spallholz
J E
JE
D000818:Animals; D001682:Biological Availability; D002417:Cattle; D002645:Chickens; D005260:Female; D005432:Flounder; D005979:Glutathione Peroxidase / Q000378:metabolism; D008099:Liver / Q000378:metabolism; D008460:Meat; D018482:Muscle, Skeletal / Q000378:metabolism; D051381:Rats; D011916:Rats, Inbred F344; D012643:Selenium / Q000172:deficiency / Q000493:pharmacokinetics*; D012645:Selenomethionine / Q000493:pharmacokinetics; D012756:Sheep; D018038:Sodium Selenite / Q000493:pharmacokinetics; D013050:Spectrometry, Fluorescence; D013552:Swine; D014413:Tuna
D012645:Selenomethionine; D005979:Glutathione Peroxidase; D012643:Selenium; D018038:Sodium Selenite