[Fibrinogen as an independent cardiovascular risk factor and the question of treatment with fibrinogen-lowering drugs].
The atherosclerotic vascular disease is a progressive condition of multifactorial origin. Among cardiovascular risk factors alterations of lipid metabolism are of central role. But the haemostatic system, first of all the plasmatic fibrinogen is also highly implicated. Increased fibrinogen condition can be regarded as a strong and independent predictor of cardiovascular risk. Total cholesterol, LDL-cholesterol and plasma fibrinogen concentration as risk factors are compared. Fibrinogen lowering treatments are also summarized.
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II. Belklinika, Debreceni Orvostudományi Egyetem.
D000925:Anticoagulants / Q000008:administration & dosage*; D001161:Arteriosclerosis / Q000097:blood / Q000209:etiology* / Q000517:prevention & control; D001779:Blood Coagulation Factors / Q000032:analysis* / Q000037:antagonists & inhibitors; D002784:Cholesterol / Q000097:blood; D005260:Female; D005340:Fibrinogen / Q000032:analysis* / Q000037:antagonists & inhibitors; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications; D006949:Hyperlipidemias / Q000150:complications; D006973:Hypertension / Q000150:complications; D008074:Lipoproteins / Q000097:blood; D008297:Male; D009765:Obesity; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects
D000925:Anticoagulants; D001779:Blood Coagulation Factors; D008074:Lipoproteins; D005340:Fibrinogen; D002784:Cholesterol