title: Serum interleukin-5 levels in a case with allergic granulomatous angiitis.
abstract: A 50-year-old woman with allergic granulomatous angiitis (AGA) presented with an elevated serum interleukin-5 (IL-5) level upon admission to a hospital. Administration of prednisolone showed marked improvement of asthmatic symptoms, reduced eosinophil counts of peripheral blood, and normalized serum IL-5 levels. This is the first report describing an elevated serum level of IL-5 in AGA. The present findings suggest that IL-5 is involved in the pathogenesis of AGA.
authors.affiliation: Department of Clinical Research, Kure Kyosai Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Shiota
authors.forename: H
authors.initials: H
authors.lastname: Matsumoto
authors.forename: Y
authors.initials: Y
authors.lastname: Kanehisa
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.forename: K
authors.initials: K
authors.lastname: Kanazawa
authors.forename: J
authors.initials: J
authors.lastname: Hiyama
authors.forename: T
authors.initials: T
authors.lastname: Ono
authors.forename: M
authors.initials: M
authors.lastname: Marukawa
authors.forename: H
authors.initials: H
authors.lastname: Mashiba
mesh_terms: D015415:Biomarkers / Q000097:blood; D015267:Churg-Strauss Syndrome / Q000097:blood* / Q000188:drug therapy / Q000209:etiology; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D015848:Interleukin-5 / Q000097:blood*; D007958:Leukocyte Count; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D015415:Biomarkers; D005938:Glucocorticoids; D015848:Interleukin-5; D011239:Prednisolone