title: Silicone breast implants and connective tissue disease: an overview.
abstract: Silicone breast implants have been implicated in the possible pathogenesis of various connective tissue diseases. These findings have had a major impact not only on the medical and legal communities, but also on the community at large. In this communication, we review the history of the breast implant controversy, and examine the medical evidence regarding the possible link of silicone gel implants with connective tissue disorders such as scleroderma, rheumatoid arthritis, and lupus. Finally, we give a broad overview of the topic and offer some general suggestions regarding the care of patients who have silicone breast implants.
authors.affiliation: Department of Medicine Mount Sinai School of Medicine, New York, NY 10029, USA.
authors.forename: H
authors.initials: H
authors.lastname: Spiera
authors.forename: R F
authors.initials: RF
authors.lastname: Spiera
mesh_terms: D018427:Breast Implants / Q000009:adverse effects*; D003240:Connective Tissue Diseases / Q000209:etiology*; D005260:Female; D005782:Gels; D006801:Humans; D016462:Mammaplasty / Q000009:adverse effects; D012828:Silicones / Q000009:adverse effects*
chemical_list: D005782:Gels; D012828:Silicones