Autoimmune diabetic neuropathy.
Recent work has shown that inflammatory vasculopathy is commonly seen in biopsies of diabetic patients with neuropathy. Most of these patients have had syndromes consistent with proximal diabetic neuropathy or amyotrophy. This suggests that inflammatory vasculopathy is important in the pathogenesis of these disorders. Immunosuppressive therapy may benefit many of these patients.
Krendel
D A
DA
Department of Pathology and Neurology, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
Zacharias
A
A
Younger
D S
DS
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D015703:Antigens, CD / Q000276:immunology; D003929:Diabetic Neuropathies / Q000188:drug therapy / Q000276:immunology* / Q000473:pathology; D005267:Femoral Nerve / Q000473:pathology; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D007378:Interleukins / Q000276:immunology; D013497:Sural Nerve / Q000473:pathology; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology
D000305:Adrenal Cortex Hormones; D015703:Antigens, CD; D016756:Immunoglobulins, Intravenous; D007378:Interleukins; D014409:Tumor Necrosis Factor-alpha