Post-transcriptional regulation: the dawn of PTB.
The 'polypyrimidine-tract-binding protein' (PTB) participates in the control of alternative processing and translation of various RNAs, and may operate as a multifunctional regulator of tissue-specific gene expression.
Valcárcel
J
J
Gene Expression Programme, European Molecular Biology Laboratory, Heidelberg, Germany.
Gebauer
F
F
D017398:Alternative Splicing / Q000187:drug effects; D000818:Animals; D004268:DNA-Binding Proteins / Q000235:genetics* / Q000502:physiology*; D005786:Gene Expression Regulation / Q000187:drug effects; D038941:Polypyrimidine Tract-Binding Protein; D012323:RNA Processing, Post-Transcriptional / Q000187:drug effects; D016601:RNA-Binding Proteins / Q000235:genetics* / Q000502:physiology*
D004268:DNA-Binding Proteins; D016601:RNA-Binding Proteins; D038941:Polypyrimidine Tract-Binding Protein