title: Respiratory symptoms, across-shift lung function changes and lifetime exposures of welders in New Zealand.
abstract: OBJECTIVE
  The possibility was investigated that exposure to welding fumes causes an acute decrease in pulmonary function.
  
  
  METHODS
  Changes in the pulmonary function of 62 current welders and 75 nonwelders at the same sites and the relationship with work-related symptoms were recorded.
  
  
  RESULTS
  Work-related cough was reported by 22.6% of the current welders and 6.7% of the nonwelders [odds ratio (OR) 4.1, 95% confidence interval (95% CI) 1.5-11.5], and the respective figures for at least 1 work-related symptom were 30.7% and 16.0% (OR 2.3, 95% CI 1.0-5.2). The groups' preshift lung function did not differ. The mean percentage change from the base-line value of the forced expiratory volume in 1 s (FEV1.0) after 15 minutes of work was -2.8% (range -29.3% to +20.9%) for the current welders and +1.0% (range -20.7% to +22.6%) for the nonwelders (P = 0.01). A multivariate analysis identified current welding as the most significant risk factor for a decrease of at least 5% in FEV1.0 after 15 minutes, the risk being greater for those with no local exhaust ventilation (OR 22.4, 95% CI 4.5-113.4) than for those with personal protection only (OR 16.0, 95% CI 2.1-122.9) and those with local exhaust ventilation (OR 2.8, 95% CI 0.2-41.2) or passive exposure only (OR 2.0, 95% CI 0.5-8.8).
  
  
  CONCLUSIONS
  An acute decrease in FEV1.0 in relation to work is more prevalent among welders than among nonwelders, and is more common among welders without local exhaust ventilation than among those with it.
authors.affiliation: Wellington Asthma Research Group, Department of Medicine, Wellington School of Medicine, New Zealand. warg.sec@wnmeds.ac.nz
authors.forename: D
authors.initials: D
authors.lastname: Fishwick
authors.forename: L M
authors.initials: LM
authors.lastname: Bradshaw
authors.forename: T
authors.initials: T
authors.lastname: Slater
authors.forename: N
authors.initials: N
authors.lastname: Pearce
mesh_terms: D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D003430:Cross-Sectional Studies; D005260:Female; D005541:Forced Expiratory Volume / Q000187:drug effects; D006801:Humans; D015994:Incidence; D008171:Lung Diseases / Q000453:epidemiology / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009520:New Zealand / Q000453:epidemiology; D016273:Occupational Exposure / Q000009:adverse effects* / Q000706:statistics & numerical data; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects / Q000453:epidemiology; D014896:Welding; D014940:Work Schedule Tolerance
chemical_list: D000395:Air Pollutants, Occupational