title: Lymphocyte homeostasis.
abstract: B- and T-lymphocyte populations have an independent homeostatic regulation of resting (B and T) and activated (B) or memory (T) cell compartments. This organization may provide an efficient mechanism to ensure simultaneously a first natural barrier of protection against common pathogens, the maintenance of immunological T-cell memory and a reservoir of repertoire diversity capable of dealing with new antigenic challenges.
authors.affiliation: INSERM U345, Institut Necker, 156 Rue Vaugirard, Paris, 75015, France.
authors.forename: C
authors.initials: C
authors.lastname: Tanchot
authors.forename: M M
authors.initials: MM
authors.lastname: Rosado
authors.forename: F
authors.initials: F
authors.lastname: Agenes
authors.forename: A A
authors.initials: AA
authors.lastname: Freitas
authors.forename: B
authors.initials: B
authors.lastname: Rocha
mesh_terms: D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D001854:Bone Marrow Cells; D006706:Homeostasis; D007156:Immunologic Memory; D008213:Lymphocyte Activation; D051379:Mice; D018448:Models, Immunological; D013601:T-Lymphocytes / Q000276:immunology*; D013950:Thymus Gland