title: Role of host immune response in the occurrence of gastropathy in rats infected with larval Taenia taeniaeformis.
abstract: Decrease of spleen weight from peak to control levels together with a corresponding decline of serum IgG level at the onset of gastric hyperplasia in Taenia taeniaeformis-infected euthymic rats, may indicate that a form of down regulation of host immune response during the course of larval T. taeniaeformis infection could facilitate the occurrence of gastropathy in rats. Gastric hyperplasia developed in T. taeniaeformis-infected athymic nude rats, indicating that occurrence of gastropathy associated with larval T. taeniaeformis infection in the rat is T cell independent. Apparently, gastric hyperplasia appeared early in nude rats which suggests that absence of T cell-mediated response could have facilitated its early occurrence.
authors.affiliation: Department of Disease Control, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
authors.forename: J A
authors.initials: JA
authors.lastname: Abella
authors.forename: Y
authors.initials: Y
authors.lastname: Oku
authors.forename: N
authors.initials: N
authors.lastname: Nonaka
authors.forename: M
authors.initials: M
authors.lastname: Ito
authors.forename: M
authors.initials: M
authors.lastname: Kamiya
mesh_terms: D000818:Animals; D003551:Cysticercosis / Q000276:immunology* / Q000473:pathology*; D003552:Cysticercus / Q000302:isolation & purification*; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology*; D007074:Immunoglobulin G / Q000097:blood; D008099:Liver / Q000469:parasitology* / Q000473:pathology; D008297:Male; D009929:Organ Size; D051381:Rats; D011923:Rats, Nude; D017208:Rats, Wistar; D013154:Spleen / Q000276:immunology / Q000473:pathology; D013950:Thymus Gland / Q000276:immunology
chemical_list: D007074:Immunoglobulin G