Lymphadenectomy in gastrointestinal surgery for malignancy.
In a randomised study 25 patients with gastrointestinal surgery combined with extended lymphadenectomy (three field lymphadenectomy in case of esophageal cancer, D2 lymphadenectomy in case of gastric cancer) has been compared to the same number of patients with limited lymphadenectomy (D1). The operation time and the need for blood transfusion has increased in the extended lymphadenectomy group. The complication rate was more than doubled in the extended lymphadenectomy group, due to fluid or lymph collection, lymphatic edema, and infection. The mapping and staging was superior in extended lymphadenectomy group, but increased morbidity and mortality has been found in this group. However the favourable effect of extended lymphadenectomy on survival needs further long-term studies and proofs.
Jakab
F
F
Department of Surgery, Uzsoki Teaching Hospital, Budapest, Hungary.
Baranyai
L
L
Baranyai
Z
Z
Országh
A
A
Mayer
A
A
Bajtai
A
A
D001803:Blood Transfusion; D004938:Esophageal Neoplasms / Q000601:surgery*; D005122:Exudates and Transudates; D006801:Humans; D008137:Longitudinal Studies; D008196:Lymph; D008197:Lymph Node Excision / Q000009:adverse effects / Q000379:methods*; D008207:Lymphatic Metastasis / Q000473:pathology; D008209:Lymphedema / Q000209:etiology; D009367:Neoplasm Staging; D013274:Stomach Neoplasms / Q000601:surgery*; D013530:Surgical Wound Infection / Q000209:etiology; D015996:Survival Rate; D013997:Time Factors; D016896:Treatment Outcome