title: [Ultrasonographic and pathologic differences between non-palpable prostate cancer (T1c) and palpable lesions detected with rectal examination].
abstract: OBJECTIVE
  To determine whether non-palpable cancers (T1c) have different ultrasound and pathological features from other palpable cancers of the prostate gland.
  
  
  METHODS
  PSA levels, ultrasound features and Gleason score in 178 patients diagnosed with prostate cancer between 1994-1995 were compared. Correlation of pathological findings in surgical sections from 47 patients undergoing radical prostatectomy.
  
  
  RESULTS
  22% tumours were non-palpable. No difference was observed between both age groups (p = 0.5) and PSA levels (p = 0.09). Differences were noted in favour of palpable cancer in PSAD (p = 0.01), incidence of ultrasound nodes (p < 0.001), capsule changes (p < 0.001), seminal vesicles (p < 0.001), Gleason score (p = 0.006) and bone scan (p < 0.05). Two (14%) patients with non-palpable cancer showed no tumour in the prostatectomy section. Apart from these 2 patients, no differences were found between both groups in terms of Gleason score (p = 0.3), local stage (p = 0.7) and node involvement (p = 0.4) in patients undergoing radical prostatectomy.
  
  
  CONCLUSIONS
  86% patients with non-palpable prostate cancer has clinically significant tumours and showed no differences from the rest of tumours undergoing radical prostatectomy.
authors.affiliation: Servicio de Urología, H.G.U. Gregorio Marañón, Madrid.
authors.forename: F
authors.initials: F
authors.lastname: Herranz Amo
authors.forename: F
authors.initials: F
authors.lastname: Verdú Tartajo
authors.forename: J M
authors.initials: JM
authors.lastname: Díez Cordero
authors.forename: I
authors.initials: I
authors.lastname: Moncada Iribarren
authors.forename: E
authors.initials: E
authors.lastname: Lledó García
authors.forename: G
authors.initials: G
authors.lastname: Bueno Chomón
authors.forename: F
authors.initials: F
authors.lastname: Leal Hernández
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D010173:Palpation; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D012189:Retrospective Studies; D014463:Ultrasonography