title: [Behçet's disease with a fatal evolution].
abstract: Behçet disease in an inflammatory systemic disease, of unknown etiology. Usually it is defined by a triad; buccal ulcerations, genital ulcerations and uveitis. Treatment is based on steroids and in difficult cases cyclosporina or cytotoxic agents could be used. We present a case of Behçet disease in a young male. The first symptoms were retrobulbar optic neuropathy, followed by buccal and genital ulcerations. For beginning the treatment was based on steroids, but the disease was more and more severe, so that the left eye lost its function because of an inflammatory maculopathy and new symptoms arose. We started treatment with cyclosporina (5 mg/kg/day), but we had to stopped it 3 months latter because of renal function's failure.
authors.affiliation: Clinica oftalmologică Cluj.
authors.forename: C
authors.initials: C
authors.lastname: Stan
authors.forename: A M
authors.initials: AM
authors.lastname: Săceleanu
mesh_terms: D000208:Acute Disease; D000328:Adult; D001528:Behcet Syndrome / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D016572:Cyclosporine / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D017809:Fatal Outcome; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D009902:Optic Neuritis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D011241:Prednisone / Q000627:therapeutic use
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D003520:Cyclophosphamide; D011241:Prednisone