Role of endogenous enteric organisms in the reactivation of arthritis.
Reactive arthritis is an acute form of arthritis apparently caused by a combination of bacterial infection and genetic influences. Recent experiments using an animal model suggest that certain bacterial cell wall polymers originating from endogenous enteric bacteria may be responsible for the condition.
Lichtman
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Department of Pediatrics, University of North Carolina, Chapel Hill 27599-7220, USA.
D000818:Animals; D030801:Animals, Genetically Modified; D001168:Arthritis / Q000235:genetics / Q000382:microbiology*; D004195:Disease Models, Animal; D015796:HLA-B27 Antigen / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D007082:Ileum / Q000601:surgery; D007239:Infections / Q000150:complications*; D007422:Intestines / Q000382:microbiology; D007583:Jejunum / Q000601:surgery; D008954:Models, Biological; D011135:Polysaccharides, Bacterial / Q000633:toxicity; D051381:Rats
D015796:HLA-B27 Antigen; D011135:Polysaccharides, Bacterial