title: Infantile myofibromatosis: a solitary lesion involving the upper lip.
abstract: Infantile myofibromatosis is a rare disease characterized by myofibroblastic proliferation, and typically occurs in early infancy. There is a wide spectrum of clinical presentation, which may involve various kinds of tissues in the body. Skin and subcutaneous lesions were the types of tissue most often seen. Although a multicentric form may behave aggressively, a solitary form of the tumor is benign with the possibility of spontaneous regression. Conservative management is justified after proper pathological diagnosis if the tumor involves an aesthetically important area. A case of solitary infantile myofibromatosis involving the upper lip is presented. Partial excision for biopsy was performed and long-term observation was undertaken. The tumor disappeared 3 years postoperatively.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Taipei, Taiwan.
authors.forename: L J
authors.initials: LJ
authors.lastname: Lo
authors.forename: C
authors.initials: C
authors.lastname: Hsueh
authors.forename: M S
authors.initials: MS
authors.lastname: Noordhoff
authors.forename: Y R
authors.initials: YR
authors.lastname: Chen
mesh_terms: D000199:Actins / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D006801:Humans; D007223:Infant; D008048:Lip Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D008297:Male; D018224:Myofibromatosis / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D009365:Neoplasm Regression, Spontaneous; D014746:Vimentin / Q000032:analysis
chemical_list: D000199:Actins; D014408:Biomarkers, Tumor; D014746:Vimentin