title: Left ventricular morphology in chronic renal failure by echocardiography.
abstract: M-mode, two-dimensional, and Doppler echocardiography were performed in 38 chronic renal failure (CRD) patients on conservative management, 35 patients on hemodialysis, and 36 matched controls. The controls were matched for age, sex, and comorbidities. The incidence of hypertension, left ventricular (LV) end diastolic volume, LV end systolic volume, and LV mass index were significantly higher in patients on hemodialysis compared to the controls. The LV parameters in the predialysis patients were not significantly different from the controls, except the LV end systolic internal dimensions were significantly higher in the CRF patients. Multiple regression analysis underscored the strong association between increase in LV mass index (LVMI) and hypertension. The diabetic patients with renal failure had large LV internal diameter and end diastolic volume compared to non-diabetics. Systolic function was well preserved even in hypertensive and diabetic patients with uremia. The incidence of diastolic dysfunction and asymmetrical septal hypertrophy were not significantly different in the three groups of patients.
authors.affiliation: Department of Nephrology, St. John's Medical College Hospital, Bangalore, India.
authors.forename: D S
authors.initials: DS
authors.lastname: Raj
authors.forename: S
authors.initials: S
authors.lastname: D'Mello
authors.forename: S
authors.initials: S
authors.lastname: Somiah
authors.forename: S D
authors.initials: SD
authors.lastname: Sheeba
authors.forename: K
authors.initials: K
authors.lastname: Mani
mesh_terms: D003928:Diabetic Nephropathies / Q000503:physiopathology; D004452:Echocardiography; D015150:Echocardiography, Doppler; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D017379:Hypertrophy, Left Ventricular / Q000503:physiopathology; D007676:Kidney Failure, Chronic / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012044:Regression Analysis; D006435:Renal Dialysis; D016277:Ventricular Function, Left