[Flow cytometry of bone marrow cells in health, anemias of different etiology and acute leukemias].
The distribution of bone marrow cells by stages of cell cycle was studied by flow cytometry in 26 normal subjects and 107 adult patients (42 with anemias and 65 with acute lymphoblastic or myeloblastic leukemias). Normal myelokaryocyte cell cycle is rather stable, which manifests by low variability of cells. In anemias and, more so, in leukemias the proliferative status of cells varies within a wide range, which is explained by unstable and ineffective hemopoiesis.
Shmarov
D A
DA
Kuchma
Iu M
IuM
Kozinets
G I
GI
D000293:Adolescent; D000328:Adult; D000368:Aged; D000740:Anemia / Q000175:diagnosis* / Q000473:pathology; D000741:Anemia, Aplastic / Q000175:diagnosis / Q000473:pathology; D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis / Q000473:pathology; D000752:Anemia, Pernicious / Q000175:diagnosis / Q000473:pathology; D001854:Bone Marrow Cells / Q000166:cytology*; D002453:Cell Cycle; D005260:Female; D005434:Flow Cytometry; D006410:Hematopoiesis; D006801:Humans; D007938:Leukemia / Q000175:diagnosis* / Q000473:pathology; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis / Q000473:pathology