title: Treatment of recurrent dislocation of the temporomandibular joint with type A botulinum toxin.
abstract: A case is reported of a 56-year-old woman who suffered from recurrent dislocations of the temporomandibular joint (TMJ) secondary to an exacerbated tetraspastic syndrome of multiple sclerosis. Following chemical denervation of the masseter and pterygoid muscles with injections of type A botulinum toxin, no further dislocations occurred for periods of up to four months. The treatment has been repeated five times. Some of the indications and possible adverse reactions to this therapy are discussed and comparisons made with other, conventional methods for managing recurrent dislocation of the TMJ.
authors.affiliation: Department of Neurology, Asklepios Kliniken Schildautal, Seesen, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Daelen
authors.forename: V
authors.initials: V
authors.lastname: Thorwirth
authors.forename: A
authors.initials: A
authors.lastname: Koch
mesh_terms: D000200:Action Potentials / Q000187:drug effects; D019274:Botulinum Toxins, Type A / Q000009:adverse effects / Q000627:therapeutic use*; D003714:Denervation / Q000379:methods; D004576:Electromyography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D004204:Joint Dislocations / Q000188:drug therapy* / Q000209:etiology; D008406:Masseter Muscle / Q000187:drug effects / Q000294:innervation; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications / Q000503:physiopathology; D009128:Muscle Spasticity / Q000503:physiopathology; D009465:Neuromuscular Agents / Q000009:adverse effects / Q000627:therapeutic use*; D011626:Pterygoid Muscles / Q000187:drug effects / Q000294:innervation; D012008:Recurrence; D019233:Retreatment; D013705:Temporomandibular Joint Disorders / Q000188:drug therapy* / Q000209:etiology
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A