title: The role of surgery and laser ablation in oesophageal carcinoma.
abstract: Between January 1990 and December 1994 oesophagectomy was carried out in 42 patients and comparison made with 38 who had palliative laser therapy. Apart from six patients referred after being unresectable at surgical exploration there were no agreed selection criteria, although the laser patients were in general older (mean 64 V 73 year) with a higher proportion of cardiorespiratory co-morbidity (14 per cent V 18 per cent). Lateral margins were involved in 14 per cent of known palliative resections with 50 per cent having positive nodes. The mean operating time was three hours and two chest drains inserted electively were removed after 3.6 days with mean drainage of 817 ml. The mean ICU stay was 5.4 days and 3 had radiological leaks; all but one settled conservatively. The 90 day mortality was 11.9 per cent for surgery and 34 per cent for laser patients. Twenty-three patients (61 per cent) required further courses of laser-therapy for benign anastomotic stenosis. Including the initial treatment of both groups 6.0 procedures per patient year were required in the laser groups compared with 1.1 for surgery. The 1, 2 and 3 year survival was 60 per cent, 31 per cent, 39 per cent for surgery compared with 24 per cent, 8 per cent, 3 per cent for laser--12 surgical patients are still alive and well at mean of 29 months (range 16-68). Surgery where possible with acceptable morbidity and mortality offers good palliation and long-term survival is possible; selection criteria for palliation only need to be defined.
authors.affiliation: Department of Surgery, Mater Misericordiae Hospital, Dublin.
authors.forename: E D
authors.initials: ED
authors.lastname: Mulligan
authors.forename: M G
authors.initials: MG
authors.lastname: O'Riordain
authors.forename: M
authors.initials: M
authors.lastname: Duggan
authors.forename: J
authors.initials: J
authors.lastname: Crowe
authors.forename: J
authors.initials: J
authors.lastname: Lennon
authors.forename: P
authors.initials: P
authors.lastname: MacMathuna
authors.forename: J M
authors.initials: JM
authors.lastname: Fitzpatrick
authors.forename: T F
authors.initials: TF
authors.lastname: Gorey
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D004938:Esophageal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016629:Esophagectomy; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010166:Palliative Care; D011183:Postoperative Complications / Q000401:mortality; D015996:Survival Rate