title: Fulminant demyelinating neuropathy mimicking cerebral death.
abstract: Guillain-Barré syndrome can very rarely present with acute quadripares and cranial nerve involvement resembling a locked-in state. We describe a very unusual case of fulminant neuropathy in a child who was previously exposed to vincristine. The clinical picture resembled brain death; however, electrodiagnostic studies led to the diagnosis of a peripheral neuropathy. Serial electrodiagnostic studies and pathologic findings confirmed demyelination.
authors.affiliation: Department of Neurology, University of California-Davis, 95616, USA.
authors.forename: N
authors.initials: N
authors.lastname: Bakshi
authors.forename: R A
authors.initials: RA
authors.lastname: Maselli
authors.forename: S M
authors.initials: SM
authors.lastname: Gospe
authors.forename: W G
authors.initials: WG
authors.lastname: Ellis
authors.forename: C
authors.initials: C
authors.lastname: McDonald
authors.forename: R N
authors.initials: RN
authors.lastname: Mandler
mesh_terms: D001706:Biopsy; D001926:Brain Death / Q000175:diagnosis*; D002648:Child; D019411:Clinical Laboratory Techniques; D003937:Diagnosis, Differential; D004568:Electrodiagnosis; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D011129:Polyradiculoneuropathy / Q000175:diagnosis* / Q000628:therapy; D013497:Sural Nerve / Q000473:pathology
chemical_list: D016756:Immunoglobulins, Intravenous