[Hormone receptors and growth factors in carcinoma of the prostate].
The therapeutic and prognostic significance of androgen receptors in prostatic carcinoma has been examined on the basis of data obtained with the different techniques used in receptor determination. Moreover, the role of some polypeptide growth factors in the regulation of prostatic cancer growth and progression has been reviewed. Great attention has been focused on in vitro models utilized to investigate androgen receptor alterations and the effects of the different positive and negative regulators of prostatic carcinoma cell growth.
Sica
G
G
Istituto di Istologia ed Embriologia, Facoltà Medicina e Chirurgia Università Cattolica del S. Cuore, Roma.
Lama
G
G
Angelucci
C
C
Zelano
G
G
D000728:Androgens / Q000378:metabolism; D006133:Growth Substances / Q000032:analysis* / Q000378:metabolism; D006801:Humans; D008297:Male; D009363:Neoplasm Proteins / Q000032:analysis* / Q000378:metabolism; D009376:Neoplasms, Hormone-Dependent; D011471:Prostatic Neoplasms / Q000737:chemistry* / Q000378:metabolism; D011944:Receptors, Androgen / Q000032:analysis* / Q000235:genetics / Q000378:metabolism; D014407:Tumor Cells, Cultured
D000728:Androgens; D006133:Growth Substances; D009363:Neoplasm Proteins; D011944:Receptors, Androgen