title: Chlamydia pneumoniae in children with otitis media.
abstract: In this study the polymerase chain reaction was used to test for the presence of Chlamydia pneumoniae DNA in 118 middle-ear aspirates from 20 children with acute otitis media (AOM) and 53 children with otitis media with effusion (OME). C. pneumoniae was detected in 8 samples obtained from 5 children with OME and, together with Streptococcus pneumoniae, in a sample from 1 child with AOM. The mean age of these five children (6.6 +/- 1.4 years) was significantly higher than that of the 48 children with OME in whom C. pneumoniae could not be detected (4.3 +/- 1.9 years). The presence of C. pneumoniae in 9.4% of the examined children with OME suggests that C. pneumoniae might be a significant supplementary factor in the etiology of this common children's disease.
authors.affiliation: Department of Medicine and Infectious Diseases, Marselisborg Hospital, University of Aarhus, Denmark.
authors.forename: M
authors.initials: M
authors.lastname: Storgaard
authors.forename: L
authors.initials: L
authors.lastname: Ostergaard
authors.forename: J S
authors.initials: JS
authors.lastname: Jensen
authors.forename: S
authors.initials: S
authors.lastname: Farholt
authors.forename: K
authors.initials: K
authors.lastname: Larsen
authors.forename: T
authors.initials: T
authors.lastname: Ovesen
authors.forename: H
authors.initials: H
authors.lastname: Nødgaard
authors.forename: P L
authors.initials: PL
authors.lastname: Andersen
mesh_terms: D000208:Acute Disease; D002648:Child; D002675:Child, Preschool; D002690:Chlamydia Infections / Q000382:microbiology* / Q000473:pathology; D016993:Chlamydophila pneumoniae / Q000235:genetics / Q000302:isolation & purification; D005260:Female; D006801:Humans; D008297:Male; D010033:Otitis Media / Q000382:microbiology* / Q000473:pathology; D010034:Otitis Media with Effusion / Q000382:microbiology* / Q000473:pathology