[How to choose and adequate antihypertensive drug depending on the type of the existing heart damage?].
The main goal of the treatment for hypertensive vascular disease is to reduce the morbidity and mortality that follow the disease. In the patient with heart disease, the choice of antihypertensive treatment will depend on several factors, all of which must be considered prior to it: type of cardiopathy and complications, pharmacokinetics of the drug-selected and its side effects, interactions with specific treatment for the main heart disease, positive or negative interactions with risk factors and, finally, its prognostic benefits. In the present study we briefly analyze this considerations in relation to different diseases such as ischemic heart disease, ventricular dysfunction (hypertrophy, systolic and diastolic dysfunction), heart rhythm disorders (sinus node dysfunction, supraventricular and ventricular ectopies), vascular pathology (cerebral and peripheral vasculopathy) and risk factors (diabetes, dyslipemia, obesity). Based on this considerations, several recommendations are done in order to choose the best antihypertensive drug in such cardiovascular diseases.
Alegría Ezquerra
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Departamento de Cardiologia y Cirugía Cardiovascular, Facultad de Medicina, Universidad de Navarra, Pamplona.
Martínez Monzonís
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Grau Sepúlveda
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D000959:Antihypertensive Agents / Q000145:classification* / Q000627:therapeutic use; D003657:Decision Making; D006331:Heart Diseases / Q000145:classification / Q000150:complications*; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy*; D017379:Hypertrophy, Left Ventricular / Q000150:complications* / Q000628:therapy; D017202:Myocardial Ischemia / Q000150:complications* / Q000628:therapy
D000959:Antihypertensive Agents