title: Percutaneous polymethylmethacrylate vertebroplasty in the treatment of osteoporotic vertebral body compression fractures: technical aspects.
abstract: OBJECTIVE
  To describe a technique for percutaneous vertebroplasty of osteoporotic vertebral body compression fractures and to report early results of its use.
  
  
  METHODS
  The technique was used over a 3-year period in 29 patients with 47 painful vertebral fractures. The technique involves percutaneous puncture of the involved vertebra(e) via a transpedicular approach followed by injection of polymethylmethacrylate (PMMA) into the vertebral body.
  
  
  RESULTS
  The procedure was technically successful in all patients, with an average injection amount of 7.1 mL PMMA per vertebral body. Two patients sustained single, nondisplaced rib fractures during the procedure; otherwise, no clinically significant complications were noted. Twenty-six patients (90%) reported significant pain relief immediately after treatment.
  
  
  CONCLUSIONS
  Vertebroplasty is a valuable tool in the treatment of painful osteoporotic vertebral fractures, providing acute pain relief and early mobilization in appropriate patients.
authors.affiliation: Department of Radiology, University of Virginia Health Sciences Center, Charlottesville 22908, USA.
authors.forename: M E
authors.initials: ME
authors.lastname: Jensen
authors.forename: A J
authors.initials: AJ
authors.lastname: Evans
authors.forename: J M
authors.initials: JM
authors.lastname: Mathis
authors.forename: D F
authors.initials: DF
authors.lastname: Kallmes
authors.forename: H J
authors.initials: HJ
authors.lastname: Cloft
authors.forename: J E
authors.initials: JE
authors.lastname: Dion
mesh_terms: D000328:Adult; D000368:Aged; D000792:Angiography; D005119:Extravasation of Diagnostic and Therapeutic Materials; D005260:Female; D005500:Follow-Up Studies; D018460:Fractures, Comminuted / Q000000981:diagnostic imaging / Q000628:therapy*; D005598:Fractures, Spontaneous / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D007267:Injections; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000000981:diagnostic imaging / Q000628:therapy*; D019904:Polymethyl Methacrylate; D019736:Prostheses and Implants; D016103:Spinal Fractures / Q000000981:diagnostic imaging / Q000628:therapy*; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D019904:Polymethyl Methacrylate