title: Application of hemodilution in microsurgical free flap transplantation.
abstract: The intra-operative hemodilution and blood auto-transfusion is a blood-saving technique that can be performed when major blood loss is expected. The effects of this technique were studied in 30 microsurgical free flap transplantation patients. Between 400-600 ml blood was collected from the patients before surgery. The patients received dextran, a balanced salt solution, and glucose with the ratio of 3:1 to the collected blood volume, bleeding, and urine before the blood auto-transfusion. There were no significant changes in RBC, HCT, MCV, blood pressure, or heart rate. Of the 30 free flaps, 28 were successful with a 93.3% survival rate. The safety of intra-operative hemodilution and autologous blood transfusion in microsurgery as well as the effect of hemodilution on transplanted flap survival are discussed in this study.
authors.affiliation: Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Beijing.
authors.forename: Q
authors.initials: Q
authors.lastname: Qiao
authors.forename: G
authors.initials: G
authors.lastname: Zhou
authors.forename: G Y
authors.initials: GY
authors.lastname: Chen
authors.forename: Y C
authors.initials: YC
authors.lastname: Ling
authors.forename: F
authors.initials: F
authors.lastname: Zhang
authors.forename: H J
authors.initials: HJ
authors.lastname: Buncke
mesh_terms: D000328:Adult; D001804:Blood Transfusion, Autologous; D003911:Dextrans; D005260:Female; D006438:Hemodilution; D006488:Hemostasis, Surgical; D006801:Humans; D008297:Male; D008866:Microsurgery; D010952:Plasma Substitutes; D013524:Surgical Flaps
chemical_list: D003911:Dextrans; D010952:Plasma Substitutes