Cardiorespiratory response to exercise in patients with exercise-induced bronchial obstruction.
OBJECTIVE
To document the characteristics of the ventilatory response to exercise in patients with exercise-induced bronchial obstruction (EIB).


METHODS
Comparative study during the period between December 1993 and March 1994.


METHODS
Ambulatory care in Ohgaki Municipal Hospital.


METHODS
We evaluated 11 children with EIB. Each subject under went symptom-limited cardiopulmonary treadmill exercise testing (Bruce protocol).


RESULTS
Patients with EIB showed a significantly lower peak oxygen consumption (peak VO2) than the control subjects. Three patients with EIB developed relative hypoventilation during incremental exercise: an increase in end-tidal carbon dioxide partial pressure (PETCO2) and a decrease in VE/VCO2 were observed at the end-stage of exercise testing.


CONCLUSIONS
These findings demonstrate that some patients with EIB develop bronchoconstriction during exercise.
Baba
R
R
Department of Pediatrics, Nagoya University School of Medicine, Japan.
Nagashima
M
M
Tauchi
N
N
Nishibata
K
K
Kondo
T
T
D000293:Adolescent; D000553:Ambulatory Care; D001250:Asthma, Exercise-Induced / Q000503:physiopathology*; D001982:Bronchial Diseases / Q000503:physiopathology; D002245:Carbon Dioxide / Q000378:metabolism; D016022:Case-Control Studies; D002648:Child; D003251:Constriction, Pathologic / Q000503:physiopathology; D005069:Evaluation Studies as Topic; D005080:Exercise Test; D005260:Female; D006321:Heart / Q000502:physiology*; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007040:Hypoventilation / Q000503:physiopathology; D008168:Lung / Q000502:physiology*; D008297:Male; D010101:Oxygen Consumption / Q000502:physiology; D010313:Partial Pressure; D005082:Physical Exertion / Q000502:physiology*; D011659:Pulmonary Gas Exchange / Q000502:physiology; D012119:Respiration / Q000502:physiology; D013990:Tidal Volume / Q000502:physiology
D002245:Carbon Dioxide