title: Colonic transit time assessed by 67 Ga-citrate in a case-series of patients with recto-sigmoid adenomas.
abstract: One plausible mechanism by which dietary factors may influence colorectal carcinogenesis is through their effect on intestinal transit time. This study examined colonic transit by means of oral 67Ga-citrate in a case-series of patients who had developed recto-sigmoid adenoma. Adenoma patients had a significantly shorter transit time than constipated patients (P = 0.01) and our results also suggest (but do not show conclusively) that colonic transit in adenoma patients is similar to that of normal controls. Although these findings require confirmation from a larger study, they raise the hypothesis that colonic transit times are not delayed in patients who harbour recto-sigmoid adenomas.
authors.affiliation: Department of Surgery, John Hunter Hospital, Newcastle, NSW, Australia.
authors.forename: C M
authors.initials: CM
authors.lastname: Chen
authors.forename: L
authors.initials: L
authors.lastname: Allen
authors.forename: M
authors.initials: M
authors.lastname: Coory
authors.forename: P
authors.initials: P
authors.lastname: Anseline
authors.forename: M
authors.initials: M
authors.lastname: Agrez
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging*; D002951:Citrates; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D005708:Gallium; D005710:Gallium Radioisotopes; D005772:Gastrointestinal Transit; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging
chemical_list: D002951:Citrates; D005710:Gallium Radioisotopes; D005708:Gallium; C103850:gallium citrate