[In vivo investigations of stress susceptibility in pigs by means of magnetic resonance spectroscopy].
31P nuclear magnetic resonance spectroscopy was performed on 19 to 55 kg weighing pigs of different MHS genotypes to study the changes of phosphorus components (inorganic phosphate --Pi, phosphocreatine--PCr and adenosine triphosphate--ATP) of muscle metabolism as well as intramuscular pH under application of halothane. Aim of the present study was to observe the changes in energy metabolism and to perform a comparison with also measured blood parameters. Both, NN and Nn pigs did not show any changes during halothane exposure in phosphorus spectra, but in all animals a partially metabolically compensated respiratoric acidosis was found. In all MHS positive pigs a rapid fall of PCr and a corresponding raise of Pi levels in muscle was observed.
Kallweit
E
E
Institut für Tierzucht und Tierverhalten, FAL, Mariensee.
Baulain
U
U
Henning
M
M
Kohn
G
G
D000255:Adenosine Triphosphate / Q000378:metabolism; D000818:Animals; D004198:Disease Susceptibility; D004734:Energy Metabolism; D005838:Genotype; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D018482:Muscle, Skeletal / Q000378:metabolism*; D010710:Phosphates / Q000378:metabolism; D010725:Phosphocreatine / Q000378:metabolism; D013312:Stress, Physiological / Q000175:diagnosis / Q000235:genetics / Q000662:veterinary*; D013552:Swine; D013553:Swine Diseases / Q000235:genetics*
D010710:Phosphates; D010725:Phosphocreatine; D000255:Adenosine Triphosphate