Spinal extramedullary hematopoiesis secondary to hepatocellular carcinoma. Case report and literature review.
A 38-year-old man, with hepatitis C and a history of intravenous drug use had hepatocellular carcinoma. Severe low back pain was the result not of metastases but of extramedullary hematopoiesis. This was not confirmed by biopsy but seemed unequivocal on magnetic resonance imaging.
O'Connor
J F
JF
Case Western Reserve University, Metrohealth Medical Center, Cleveland, Ohio 44109, USA.
Levinthal
G N
GN
Sheets
R
R
Mullen
K D
KD
D000328:Adult; D001416:Back Pain / Q000209:etiology; D006528:Carcinoma, Hepatocellular / Q000150:complications*; D004824:Epidural Space / Q000473:pathology* / Q000502:physiology; D006411:Hematopoiesis, Extramedullary; D006526:Hepatitis C / Q000150:complications; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications; D008113:Liver Neoplasms / Q000150:complications*; D008159:Lumbar Vertebrae / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male