Colonic transit time assessed by 67 Ga-citrate in a case-series of patients with recto-sigmoid adenomas.
One plausible mechanism by which dietary factors may influence colorectal carcinogenesis is through their effect on intestinal transit time. This study examined colonic transit by means of oral 67Ga-citrate in a case-series of patients who had developed recto-sigmoid adenoma. Adenoma patients had a significantly shorter transit time than constipated patients (P = 0.01) and our results also suggest (but do not show conclusively) that colonic transit in adenoma patients is similar to that of normal controls. Although these findings require confirmation from a larger study, they raise the hypothesis that colonic transit times are not delayed in patients who harbour recto-sigmoid adenomas.
Chen
C M
CM
Department of Surgery, John Hunter Hospital, Newcastle, NSW, Australia.
Allen
L
L
Coory
M
M
Anseline
P
P
Agrez
M
M
D000236:Adenoma / Q000000981:diagnostic imaging*; D002951:Citrates; D015179:Colorectal Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D005708:Gallium; D005710:Gallium Radioisotopes; D005772:Gastrointestinal Transit; D006801:Humans; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging
D002951:Citrates; D005710:Gallium Radioisotopes; D005708:Gallium; C103850:gallium citrate