title: Enumeration of flux routes through complex biochemical reactions.
abstract: In the present work, a general algorithm for enumeration of the flux routes via which a chemical species "flows" through a complex biochemical reaction is outlined and presented by way of a biological example, a kinetic model for potassium ion permeation through a voltage-gated ion channel. The algorithm is readily amenable to computer based implementation and when used in conjunction with an existing algorithm provides a convenient means for simulation of the equilibrium and steady-state isotope exchange kinetics of complex biochemical reactions.
authors.affiliation: Rockefeller University, N.Y., N.Y. 10021, USA.
authors.forename: J
authors.initials: J
authors.lastname: Wagg
authors.forename: P
authors.initials: P
authors.lastname: Sellers
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D007700:Kinetics; D008660:Metabolism; D008954:Models, Biological; D008956:Models, Chemical; D011506:Proteins / Q000378:metabolism*
chemical_list: D011506:Proteins