title: Effects of lasalocid in milk replacer of calf starter on health and performance of calves challenged with Eimeria species.
abstract: Holstein bull calves (n = 48) were purchased from local sale barns at 3 to 7 d of age and were assigned randomly to a 2 x 2 factorial arrangement of lasalocid in milk replacer (0 or 80 mg/kg) and in calf starter (3 or 44 mg/kg of dry matter). On d 10 after arrival, calves were orally dosed with 100,000 Eimeria oocysts. Intakes of calf starter and milk replacer, body weight (BW), BW gain, excretion of fecal oocysts, and fecal scores were determined. Calves fed lasalocid in milk replacer consumed more calf starter, had greater BW gain, shed fewer oocysts in feces, and scoured less frequently and less severely than did calves fed no lasalocid or those fed lasalocid in calf starter alone. The combination of lasalocid in milk replacer and in calf starter did not improve performance above that of calves fed lasalocid in milk replacer alone. Low intake of calf starter prior to weaning may provide an insufficient amount of lasalocid to control effectively the effects of coccidiosis when calves are infected with Eimeria at an early age. Use of coccidiostats in milk replacers may reduce the effects of coccidiosis in young calves that are infected with Eimeria at an early age.
authors.affiliation: Department of Animal Science, University of Tennessee, Knoxville 37901-1071, USA.
authors.forename: J D
authors.initials: JD
authors.lastname: Quigley
authors.forename: J J
authors.initials: JJ
authors.lastname: Drewry
authors.forename: L M
authors.initials: LM
authors.lastname: Murray
authors.forename: S J
authors.initials: SJ
authors.lastname: Ivey
mesh_terms: D000375:Aging; D000821:Animal Feed; D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002417:Cattle / Q000254:growth & development / Q000502:physiology*; D002418:Cattle Diseases / Q000517:prevention & control*; D003048:Coccidiosis / Q000517:prevention & control / Q000662:veterinary*; D003049:Coccidiostats / Q000008:administration & dosage* / Q000627:therapeutic use; D004539:Eimeria; D005243:Feces / Q000469:parasitology; D006304:Health Status; D007832:Lasalocid / Q000008:administration & dosage* / Q000627:therapeutic use; D008297:Male; D008892:Milk; D015430:Weight Gain
chemical_list: D003049:Coccidiostats; D007832:Lasalocid