Decidual leukocyte populations in ectopic pregnancies.
OBJECTIVE
To determine whether the recruitment of decidual leukocytes during pregnancy is the same in intrauterine pregnancies (IUPs) versus ectopic pregnancies (EPs).


METHODS
Intrauterine decidual samples from both EPs and IUPs were obtained for the evaluation of leukocyte populations.


METHODS
In vitro experiment.


METHODS
Women with EPs and women with IUPs.


METHODS
Immunohistochemical identification of decidual leukocyte populations.


RESULTS
We have analyzed the decidual leukocyte populations from three women with EPs by immunohistochemical analysis. The data demonstrate a leukocyte infiltration similar to that found in decidua from normal pregnancies.


CONCLUSIONS
These data support the hypothesis that decidual leukocyte recruitment and/or increases during pregnancy is primarily hormonally regulated.
Stewart-Akers
A M
AM
University of Pittsburgh, Pennsylvania, USA.
Krasnow
J S
JS
DeLoia
J A
JA
D015703:Antigens, CD / Q000032:analysis*; D017252:CD3 Complex / Q000032:analysis; D019002:CD56 Antigen / Q000032:analysis; D003656:Decidua / Q000166:cytology / Q000473:pathology*; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D007150:Immunohistochemistry; D017493:Leukocyte Common Antigens / Q000032:analysis; D007958:Leukocyte Count; D007962:Leukocytes / Q000276:immunology; D018950:Lipopolysaccharide Receptors / Q000032:analysis; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000473:pathology*
D015703:Antigens, CD; D017252:CD3 Complex; D019002:CD56 Antigen; D018950:Lipopolysaccharide Receptors; D017493:Leukocyte Common Antigens