title: Acid-base balance.
abstract: This article emphasizes the interactions between the respiratory and metabolic sources of acid and their clearance. It includes the chemistry of acid-based balance as expressed by the Henderson-Hasselbach equation, the principles and importance of biologic buffering systems, and a brief review of renal regulation of acid-based balance. Finally, the reader is given a set of guidelines for a systematic approach to the analysis of acid-base data.
authors.affiliation: Department of Anesthesia, Northwestern University Medical School, Chicago, Illinois, USA.
authors.forename: R A
authors.initials: RA
authors.lastname: Harrison
mesh_terms: D000136:Acid-Base Equilibrium / Q000502:physiology*; D000137:Acid-Base Imbalance / Q000175:diagnosis; D000328:Adult; D001784:Blood Gas Analysis; D002021:Buffers; D004734:Energy Metabolism / Q000502:physiology*; D017408:Guidelines as Topic; D006801:Humans; D007668:Kidney / Q000502:physiology; D012016:Reference Values; D012143:Respiratory Physiological Phenomena
chemical_list: D002021:Buffers