The influence of 0.12% chlorhexidine digluconate rinses on the incidence of infectious complications and implant success.
The effect of perioperative chlorhexidine on the frequency of infectious complications through stage II was examined. Chlorhexidine was used perioperatively in 54.6% of patients (52.5% of implants) in a Dental Implant Clinical Research Group study with a database of 2,641 implants (595 patients). With chlorhexidine, there was a significant reduction in the number of infectious complications (4.1% vs 8.7%). Two percent of implants failed in the absence of an infectious complication, whereas 12% with infectious complications failed. This sixfold difference is highly significant. Chlorhexidine may reduce microbial complications when used in the immediate perioperative period.
Lambert
P M
PM
Dental Service, Department of Veterans Affairs Medical Center, Dayton, OH, USA.
Morris
H F
HF
Ochi
S
S
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000497:Alloys; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000627:therapeutic use*; D002710:Chlorhexidine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D019992:Databases as Topic; D003722:Dental Alloys; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D017267:Dental Prosthesis Design; D019232:Dental Restoration Failure; D017886:Durapatite; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes / Q000627:therapeutic use*; D011446:Prospective Studies; D013530:Surgical Wound Infection / Q000517:prevention & control*; D014025:Titanium; D016896:Treatment Outcome; D014945:Wound Healing
D000497:Alloys; D000891:Anti-Infective Agents, Local; D003722:Dental Alloys; D015921:Dental Implants; D009067:Mouthwashes; C031462:titanium alloy (TiAl6V4); D017886:Durapatite; D014025:Titanium; C010882:chlorhexidine gluconate; D002710:Chlorhexidine