Kindler syndrome: a rare cause of desquamative lesions of the gingiva.
Kindler syndrome is a rare syndrome with cutaneous and intraoral manifestations. It has been suggested that there is an overlap between this syndrome and another called Weary syndrome. Only 68 cases of Weary and Kindler syndromes have been reported, with fewer solely attributed to Kindler syndrome. The salient cutaneous features are neonatal bullae, poikiloderma, photosensitivity, and acral atrophy. This article presents the clinical intraoral findings of two siblings of consanguineous descent diagnosed as having Kindler syndrome. Both had an erythematous and erosive appearance of the gingiva; one sibling had poor oral hygiene and a rapidly progressive form of periodontal disease; the other, whose oral hygiene was acceptable, had no detectable bone loss.
Ricketts
D N
DN
Department of Conservative Dentistry, UMDS Guy's and St Thomas' Medicaland Dental School, London, England.
Morgan
C L
CL
McGregor
J M
JM
Morgan
P R
PR
D000328:Adult; D016301:Alveolar Bone Loss / Q000235:genetics / Q000473:pathology; D001284:Atrophy; D003241:Consanguinity; D004890:Erythema / Q000235:genetics / Q000473:pathology; D005260:Female; D005882:Gingival Diseases / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008297:Male; D009910:Oral Hygiene; D010510:Periodontal Diseases / Q000235:genetics / Q000473:pathology; D010787:Photosensitivity Disorders / Q000235:genetics / Q000473:pathology; D011038:Rothmund-Thomson Syndrome / Q000235:genetics / Q000473:pathology; D012867:Skin / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000235:genetics* / Q000473:pathology; D013577:Syndrome