title: APC gene: database of germline and somatic mutations in human tumors and cell lines.
abstract: A database (http://perso.curie.fr/tsoussi ) is described, in which over 1000 mutations in the human APC gene of tumors (colon cancer predominantly) are compiled from the literature. It includes both molecular information about the mutations and clinical data about the patients. Software has been designed to analyse all this information in the database.
authors.affiliation: Hôpital Laennec Service de Chirurgie Digestive Générale et Oncologique, 42 Rue de Sevres, 75007 Paris, France. pierre.laurent-puig@biomedicale.univ-paris5.fr
authors.forename: P
authors.initials: P
authors.lastname: Laurent-Puig
authors.forename: C
authors.initials: C
authors.lastname: Béroud
authors.forename: T
authors.initials: T
authors.lastname: Soussi
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000235:genetics*; D003195:Computer Communication Networks; D016208:Databases, Factual; D017491:Genes, APC; D018095:Germ-Line Mutation; D006801:Humans; D009154:Mutation; D014407:Tumor Cells, Cultured