Acute Epstein-Barr virus infection complicated by severe thrombocytopenia.
We describe one patient with acute Epstein-Barr virus (EBV) infection associated with severe thrombocytopenia and review 36 additional cases reported in the literature. Complications of EBV infection due to severe thrombocytopenia occurred in 10 (27.0%) of 37 patients, and 2 (5.4%) of 37 patients died. Although acute EBV infections are generally benign and self-limiting, thrombocytopenia, a potentially serious complication, should not be overlooked.
Pipp
M L
ML
Department of Medicine, Graduate School of Medicine, The University of Tennessee Medical Center at Knoxville, 37920-6999, USA.
Means
N D
ND
Sixbey
J W
JW
Morris
K L
KL
Gue
C L
CL
Baddour
L M
LM
D000208:Acute Disease; D000293:Adolescent; D005260:Female; D006566:Herpesviridae Infections / Q000150:complications*; D004854:Herpesvirus 4, Human / Q000302:isolation & purification; D006801:Humans; D012720:Severity of Illness Index; D013921:Thrombocytopenia / Q000150:complications*; D014412:Tumor Virus Infections / Q000150:complications*