title: Synchronous occurrence of Wilms tumor and ganglioneuroblastoma in a child with neurofibromatosis.
abstract: A 2-year-old male with neurofibromatosis who had a Wilms tumor of the right kidney and an ipsilateral adrenal ganglioneuroblastoma is reported. Both tumors were completely removed and no recurrence occurred for 4 years after completion of the therapy. In a review of the literature, the prognosis of neurofibromatosis with these embryonal tumors is not satisfactory due to development of secondary tumors and disseminated metastases of the tumors. The synchronous occurrence of Wilms tumor and neuroblastoma in neurofibromatosis is extremely rare and this may be the first report in the world.
authors.affiliation: Department of Surgery, Branch Hospital, Nagoya University School of Medicine, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Ito
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
authors.forename: T
authors.initials: T
authors.lastname: Ito
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000473:pathology / Q000628:therapy; D002675:Child, Preschool; D004200:Diseases in Twins; D018305:Ganglioneuroblastoma / Q000473:pathology / Q000628:therapy; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology / Q000628:therapy; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000473:pathology / Q000628:therapy; D017253:Neurofibromatoses / Q000473:pathology / Q000628:therapy; D009396:Wilms Tumor / Q000473:pathology / Q000628:therapy