Vasopressin-induced amber-like skin necrosis.
Case reports about vasopressin-induced cutaneous necrosis are not frequent. Here we report a further case, of which skin manifestations included not only mottling, cyanosis, ecchymosis, bullae and gangrene, but also amber-like change in focal areas. Besides, intermittent paling of the skin with or without deep pain sensation of the limbs over non-injection sites was observed that might be a warning sign of impending skin necrosis. Based on the literature about vasopressin-induced skin necrosis we discuss the possible role of coagulation enhancement of this molecule.
Lin
R Y
RY
Department of Dermatology, Tri-Service General Hospital, Taipei, Taiwan, Republic of China.
Du
S L
SL
Yeh
H S
HS
Wang
W M
WM
D004932:Esophageal and Gastric Varices / Q000188:drug therapy; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy; D006490:Hemostatics / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010859:Pigmentation Disorders / Q000139:chemically induced* / Q000473:pathology; D012871:Skin Diseases / Q000139:chemically induced* / Q000473:pathology; D014667:Vasopressins / Q000009:adverse effects*
D006490:Hemostatics; D014667:Vasopressins