title: A study of thyroid radioiodine monitoring by Monte Carlo simulations: implications for equipment design.
abstract: Monte Carlo simulations have been performed to evaluate the design of collimated detectors used to measure 125I or 131I in the thyroid gland. Two detector sizes were simulated for each radioisotope: (i) for 125I monitoring 2.54 cm diameter and 7.62 cm diameter and 0.2 cm thickness and (ii) for 131I monitoring 2.54 cm diameter, 3.2 cm thickness and 7.62 cm diameter, 6.4 cm thickness. The virtual thyroid gland was 20 g. Activity was placed in both the gland and the remainder of the body in varying amounts to assess the efficacy of collimation. The results show that the detector should be sufficiently large so that its solid angle of acceptance when placed 15 cm anterior to the skin surface will include the whole of a moderately enlarged thyroid gland. Heavy collimation to reduce the contribution of extrathyroidal radioiodine within the subject's body is not normally required. It may be of more value as a positioning device and spacer ensuring an appropriate and constant neck to detector distance than in cutting down counts from extrathyroidal activity. In specifying a sensitive detector system for monitoring intrathyroidal radioiodine, a wide angle of acceptance and sufficient detector crystal thickness take precedence over collimation and shielding.
authors.affiliation: Human Monitoring Laboratory, Radiation Protection Bureau, Ottawa, Ontario, Canada.
authors.forename: G H
authors.initials: GH
authors.lastname: Kramer
authors.forename: M J
authors.initials: MJ
authors.lastname: Chamberlain
authors.forename: S
authors.initials: S
authors.lastname: Yiu
mesh_terms: D003198:Computer Simulation; D004867:Equipment Design; D006801:Humans; D007457:Iodine Radioisotopes / Q000378:metabolism* / Q000493:pharmacokinetics; D009010:Monte Carlo Method; D011829:Radiation Dosage; D011834:Radiation Monitoring / Q000295:instrumentation / Q000379:methods*; D011881:Radiotherapy, Computer-Assisted / Q000295:instrumentation / Q000379:methods; D013961:Thyroid Gland / Q000378:metabolism* / Q000528:radiation effects
chemical_list: D007457:Iodine Radioisotopes