title: [Targeting the gene for platelet-derived growth factor A-chain (PDGF-A) and preparation of chimeric mice with a "knockout" genome].
abstract: A vector was selected for homologous recombination to generate mouse embryonic stem cell clones with disrupted platelet-derived growth factor A (PDGF-A) chain gene. A chimeric mouse with targeted PDGF-A gene has been created.
authors.forename: I V
authors.initials: IV
authors.lastname: Makarova
authors.forename: N S
authors.initials: NS
authors.lastname: Neznanov
authors.forename: E S
authors.initials: ES
authors.lastname: Tsymbaliuk
authors.forename: L E
authors.initials: LE
authors.lastname: Andreeva
authors.forename: E S
authors.initials: ES
authors.lastname: Manuilova
authors.forename: I A
authors.initials: IA
authors.lastname: Grivennikov
authors.forename: V Z
authors.initials: VZ
authors.lastname: Tarantul
authors.forename: S M
authors.initials: SM
authors.lastname: Serov
authors.forename: E D
authors.initials: ED
authors.lastname: Adamson
authors.forename: K G
authors.initials: KG
authors.lastname: Gazarian
mesh_terms: D000818:Animals; D002678:Chimera; D005314:Embryonic and Fetal Development / Q000235:genetics; D018390:Gene Targeting; D005822:Genetic Vectors; D051379:Mice; D018345:Mice, Knockout / Q000235:genetics*; D010982:Platelet-Derived Growth Factor / Q000235:genetics*; D011995:Recombination, Genetic
chemical_list: D010982:Platelet-Derived Growth Factor; C075278:platelet-derived growth factor A