title: Effects of child-rearing by schizophrenic mothers: a 25-year follow-up.
abstract: We conducted a 25-year follow-up study of 50 children of schizophrenic mothers, consisting of 25 children reared by their mothers and 25 children reared apart. The children's adult psychiatric status was evaluated in a 3-h structured interview employing a battery of syndrome check-lists and scales. A slightly higher incidence of psychopathology (including schizophrenia-spectrum disorders) was found among the reared-apart subjects. This may possibly be attributed to their greater genetic predisposition, as suggested by their mothers' more severe illnesses. Lifetime diagnoses do not provide evidence that psychopathology in offspring at genetic risk is increased by rearing by a schizophrenic mother.
authors.affiliation: Department of Psychology, University of California, Santa Barbara, USA.
authors.forename: J
authors.initials: J
authors.lastname: Higgins
authors.forename: R
authors.initials: R
authors.lastname: Gore
authors.forename: D
authors.initials: D
authors.lastname: Gutkind
authors.forename: S A
authors.initials: SA
authors.lastname: Mednick
authors.forename: J
authors.initials: J
authors.lastname: Parnas
authors.forename: F
authors.initials: F
authors.lastname: Schulsinger
authors.forename: T D
authors.initials: TD
authors.lastname: Cannon
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002668:Child Rearing; D016241:Child of Impaired Parents / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008426:Maternal Deprivation; D009035:Mothers / Q000523:psychology*; D010553:Personality Development; D011569:Psychiatric Status Rating Scales; D011599:Psychopathology; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis / Q000235:genetics*; D012565:Schizophrenic Psychology