Seasonal cyclothymia to seasonal bipolar affective disorder: a double switch after stroke.
The appearance of bipolar affective disorder after stroke depends on the presence of two factors: a predisposing factor of either genetic loading or subcortical atrophy, and a lesion of specific corticolimbic pathways involving the right hemisphere. Whether cyclothymia and seasonal affective disorder further predispose to poststroke affective disorder is not clear. A case is described which highlights these issues. The aetiological factors, pathophysiology, and diagnosis are discussed.
Kumar
S
S
PRiSM, Institute of Psychiatry, London, UK.
Jacobson
R R
RR
Sathananthan
K
K
D000368:Aged; D000369:Aged, 80 and over; D002561:Cerebrovascular Disorders / Q000523:psychology*; D003527:Cyclothymic Disorder / Q000175:diagnosis / Q000209:etiology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D016574:Seasonal Affective Disorder / Q000175:diagnosis / Q000209:etiology*; D012621:Seasons