title: [Two cases of severe metabolic acidosis after monitoring of evoked spinal cord potential].
abstract: Evoked spinal cord potential (ESCP) elicited by direct spinal cord stimulation has been applied to monitor the spinal cord function during spinal surgery. We report here two patients who showed excessive muscle contraction and developed severe metabolic acidosis as a result of the stimulation of spinal cord to measure ESCP. These changes were prevented by vecuronium administration prior to ESCP monitoring. These results suggest that excessive muscle contraction by direct spinal cord stimulation may lead to metabolic acidosis. In conclusion, the use of a non-depolarizing muscle relaxant is recommended to prevent the adverse effects of ESCP monitoring.
authors.affiliation: Department of Anesthesiology, Sapporo Medical University School of Medicine.
authors.forename: Y
authors.initials: Y
authors.lastname: Tohdoh
authors.forename: S
authors.initials: S
authors.lastname: Sumita
authors.forename: H
authors.initials: H
authors.lastname: Iwasaki
authors.forename: T
authors.initials: T
authors.lastname: Kawamata
authors.forename: H
authors.initials: H
authors.lastname: Tsuchida
authors.forename: A
authors.initials: A
authors.lastname: Namiki
mesh_terms: D000138:Acidosis / Q000209:etiology* / Q000517:prevention & control; D000293:Adolescent; D005071:Evoked Potentials; D005260:Female; D006801:Humans; D008297:Male; D016343:Monitoring, Intraoperative / Q000009:adverse effects*; D003473:Neuromuscular Nondepolarizing Agents / Q000008:administration & dosage; D011292:Premedication; D013116:Spinal Cord / Q000502:physiology*; D013131:Spine / Q000601:surgery; D014673:Vecuronium Bromide / Q000008:administration & dosage
chemical_list: D003473:Neuromuscular Nondepolarizing Agents; D014673:Vecuronium Bromide