title: [A case of medullary carcinoma of the thyroid gland: metachronous bilateral metastasis of the neck and mediastinal lymph nodes were treated successfully by staged resection].
abstract: This patient, a 52-year-old male, underwent subtotal thyroidectomy on the diagnosis of medullary carcinoma of the thyroid gland in 1980 and postoperative course was uneventful. Since November 1990 he had a persistent diarrhea for 6 months and was admitted to the hospital for the further examination on June 1991. The serum CEA and calcitonine level was very high and chest CT scan findings showed the swelling of right neck and mediastinal lymph nodes. Dissection of the lymph nodes was performed by anterior approach which was gained through a proximal median sternotomy extended into the anterior fourth intercostal space as well as to the base of the neck on the right side. On the pathological examination it was metastasis of medullary carcinoma of the thyroid gland. And 50 months later after second operation he had a persistent diarrhea once again. Left neck and mediastinal lymph node metastasis was detected by chest CT with high serum CEA and calcitonine level. Similarly resection was performed by the same anterior approach on the left side. Irrespective of the extended resection he was free of severe complication; he is still alive 10 months after the third operation without any evidence of recurrence and his current performance status is very good.
authors.affiliation: Department of Surgery, Tuboi Hospital, Jisankai Medical Institute, Kohriyama, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Hiyoshi
authors.forename: H
authors.initials: H
authors.lastname: Iwanami
authors.forename: K
authors.initials: K
authors.lastname: Narita
authors.forename: M
authors.initials: M
authors.lastname: Tachibana
authors.forename: M
authors.initials: M
authors.lastname: Sakonji
authors.forename: E
authors.initials: E
authors.lastname: Tsuboi
authors.forename: H
authors.initials: H
authors.lastname: Kato
mesh_terms: D018276:Carcinoma, Medullary / Q000556:secondary / Q000601:surgery*; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods*; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012086:Reoperation; D013964:Thyroid Neoplasms / Q000473:pathology / Q000601:surgery*