Clinical and economic outcomes of expanded criteria donors in renal transplantation.
Although graft and patient survival rates were similar between recipients of kidneys from ECDs and non-ECDs, transplantation with organs from ECDs was significantly more expensive. Multivariate analysis using stepwise linear regression demonstrated length of stay to be a strong proxy for total hospital costs. Inherent tensions between the overall good clinical outcomes associated with the use of ECDs in terms of graft survival and the markedly increased costs seen with these organs are evident.
Whiting
J F
JF
Department of Surgery, University of Cincinnati College of Medicine, OH 45267-0558, USA.
Golconda
M
M
Smith
R
R
O'Brien
S
S
First
M R
MR
Alexander
J W
JW
D000367:Age Factors; D002102:Cadaver; D002675:Child, Preschool; D003365:Costs and Cost Analysis; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation / Q000191:economics / Q000401:mortality / Q000502:physiology*; D008875:Middle Aged; D009820:Ohio; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate; D014019:Tissue Donors / Q000706:statistics & numerical data / Q000600:supply & distribution*; D009927:Tissue and Organ Procurement / Q000458:organization & administration; D016896:Treatment Outcome