title: A case of fibrin sealant application for closing benign trachea-esophageal fistula (TEF).
abstract: Surgical treatment of upper airway-esophageal communications are frequently lead to failure. Having previous experience of thoracic administration of Tissucol fibrin glue authors attempted the local application in a case of TEF. A young lady suffering from myasthenia gravis required longstanding artificial ventilation. Not surprisingly a TEP developed in the area of the tracheostomy. There was no room for surgical repair of the TEF. Two administrations of rapid acting form of Tissucol was needed following local astringent therapy and enzymatic debridement to achieve a complete and permanent closure of a tracheobronchial sinus in a diameter of 5 mm. In addition of meticulous technique and of general supporting therapy special attention was paid to the followings: 1/healthy wound edges 2/ local infection control 3/dry environment 4/patient building up strategy.
authors.affiliation: Department of Thoracic Surgery, First Surgical Clinic, Medical University of Pécs, Hungary.
authors.forename: I
authors.initials: I
authors.lastname: Benkó
authors.forename: T F
authors.initials: TF
authors.lastname: Molnár
authors.forename: O P
authors.initials: OP
authors.lastname: Horváth
mesh_terms: D000328:Adult; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D001252:Astringents / Q000627:therapeutic use; D057487:Enzyme Therapy; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D009157:Myasthenia Gravis / Q000628:therapy; D012121:Respiration, Artificial / Q000009:adverse effects; D014014:Tissue Adhesives / Q000627:therapeutic use*; D014138:Tracheoesophageal Fistula / Q000209:etiology / Q000628:therapy*; D014139:Tracheostomy / Q000009:adverse effects; D014867:Water; D014945:Wound Healing
chemical_list: D000891:Anti-Infective Agents, Local; D001252:Astringents; D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives; D014867:Water