title: Norgestomet implants prevent pregnancy in beef heifers on pasture.
abstract: The efficacy of erodible norgestomet implants for preventing pregnancy in postpubertal heifers was evaluated in two experiments at five locations each. Heifers (n = 896) within each study location were stratified by weight and allotted randomly to receive an ear implant containing either 0, 24, 36, or 48 mg of norgestomet (d 0). Heifers were exposed to fertile bulls immediately after implantation for 75 d (d 0 to 74) in Exp. 1 (n = 476) or for 80 d (d 75 to 154) in Exp. 2 (n = 420). Weights were recorded on d 0 and 74 (Exp. 1 and 2) and d 154 (Exp. 2). Each heifer was palpated rectally for pregnancy at the end of each experiment. Pregnancy rates were higher (P < .01) for control heifers (0 mg implant) than for heifers that received 24, 36, or 48 mg of norgestomet. In Exp. 1, pregnancy rates were 96, 29, 6, and 4% for heifers that received 0, 24, 36, and 48 mg implants of norgestomet, respectively. In Exp. 2, pregnancy rates were 85, 36, 19, and 9% for heifers that received 0, 24, 36, and 48 mg implants of norgestomet, respectively. Estrous activity during the first 3 wk of bull exposure was reduced (P < .05) among heifers that received norgestomet implants compared to control heifers but was not completely abolished at any dosage in Exp. 1. During the first 75 d of Exp. 1 and 2, heifers treated with 36 or 48 mg norgestomet implants gained weight faster (P < .05) than control heifers. Combined across both experiments, ADG during the first 74 d were .53, .56, .59, and .60 kg/d for heifers treated with 0, 24, 36, and 48 mg implants of norgestomet, respectively. These data indicate that norgestomet implants increased rate of weight gain, reduced estrous activity, and reduced the occurrence of pregnancy in heifers on pasture.
authors.affiliation: Colorado State University, Fort Collins 80523, USA.
authors.forename: T W
authors.initials: TW
authors.lastname: Geary
authors.forename: J J
authors.initials: JJ
authors.lastname: Reeves
authors.forename: D W
authors.initials: DW
authors.lastname: Schafer
authors.forename: R R
authors.initials: RR
authors.lastname: Evans
authors.forename: R D
authors.initials: RD
authors.lastname: Randel
authors.forename: L M
authors.initials: LM
authors.lastname: Rutter
authors.forename: R G
authors.initials: RG
authors.lastname: Sasser
authors.forename: R
authors.initials: R
authors.lastname: Guardia
authors.forename: B
authors.initials: B
authors.lastname: Alexander
authors.forename: D
authors.initials: D
authors.lastname: Holcombe
authors.forename: D R
authors.initials: DR
authors.lastname: Hanks
authors.forename: D B
authors.initials: DB
authors.lastname: Faulkner
mesh_terms: D000821:Animal Feed; D000818:Animals; D002417:Cattle / Q000502:physiology*; D004305:Dose-Response Relationship, Drug; D004343:Drug Implants; D004971:Estrus / Q000187:drug effects / Q000502:physiology; D005260:Female; D005298:Fertility / Q000187:drug effects / Q000502:physiology; D008297:Male; D011247:Pregnancy; D018873:Pregnancy Rate; D011270:Pregnancy, Animal / Q000187:drug effects* / Q000502:physiology; D011282:Pregnenediones / Q000008:administration & dosage / Q000494:pharmacology*; D045167:Progesterone Congeners / Q000008:administration & dosage / Q000494:pharmacology*; D011897:Random Allocation; D015430:Weight Gain / Q000187:drug effects / Q000502:physiology
chemical_list: D004343:Drug Implants; D011282:Pregnenediones; D045167:Progesterone Congeners; C100284:norgestomet