title: Complementary DNA cloning and chromosomal mapping of a novel phosphatidylinositol kinase gene.
abstract: A cDNA for a putative new member for phosphatidylinositol kinase family was cloned from an adult human whole brain cDNA library. The predicted translation product was composed of 961 amino acid residues and contained a sequence feature characteristic for lipid/protein kinases. The messenger RNA was ubiquitously expressed in various tissues, while relatively higher expression was observed in heart, skeletal muscle and testis. The chromosomal location of the gene was determined by fluorescence in situ hybridization and PCR-based analyses with both a human/rodent monochromosomal hybrid cell panel and a radiation hybrid mapping panel.
authors.affiliation: Genome Research Group, National Institute of Radiological Sciences, Chiba, Japan. t_saito@nirs.go.jp
authors.forename: T
authors.initials: T
authors.lastname: Saito
authors.forename: N
authors.initials: N
authors.lastname: Seki
authors.forename: H
authors.initials: H
authors.lastname: Ishii
authors.forename: M
authors.initials: M
authors.lastname: Ohira
authors.forename: A
authors.initials: A
authors.lastname: Hayashi
authors.forename: S
authors.initials: S
authors.lastname: Kozuma
authors.forename: T
authors.initials: T
authors.lastname: Hori
mesh_terms: D019870:1-Phosphatidylinositol 4-Kinase / Q000235:genetics*; D000328:Adult; D000595:Amino Acid Sequence; D001483:Base Sequence; D002874:Chromosome Mapping; D002878:Chromosomes, Human, Pair 1; D003001:Cloning, Molecular; D018076:DNA, Complementary; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction
chemical_list: D018076:DNA, Complementary; D019870:1-Phosphatidylinositol 4-Kinase