title: Diagnostic decision support in suspected acute appendicitis: validation of a simplified scoring system.
abstract: OBJECTIVE
  To validate a simplified scoring system as an aid to the diagnosis of acute appendicitis.
  
  
  METHODS
  Open prospective study.
  
  
  METHODS
  County district hospital, and university hospital, Sweden.
  
  
  METHODS
  1167 Patients with suspected appendicitis.
  
  
  METHODS
  Correlation between scoring system and final diagnosis.
  
  
  RESULTS
  A total of 475 patients were operated on and 392 (82.5%) of these had histologically verified appendicitis. The negative laparotomy rate was 17.5% (11.2% for men and 25.4% for women). The sensitivity of the scoring system for appendicitis at the main cut-off point (score -2 or more) was 0.73 and the specificity was 0.87. At the cut-off level (score - 17 or less) for predicting non-specific abdominal pain (NSAP) the proportion of correctly classified patients was 0.72 and the proportion of false negatives (patients with appendicitis classified as NSAP) was 0.14. Analysis of the area under the receiver operating characteristic (ROC) curve showed that the scoring system performed slightly worse in the university hospital (area 0.83) than in the district hospital where it was originally developed (area 0.89).
  
  
  CONCLUSIONS
  The scoring system was a valid instrument for discriminating between acute appendicitis and NSAP in the two centres studied. Use of the scoring system in daily clinical work was associated with a reduced rate of negative laparotomies.
authors.affiliation: Department of Surgery, Nacka Hospital, Stockholm, Sweden. gyorgy.fenyo@kirurg.sos.sll.se
authors.forename: G
authors.initials: G
authors.lastname: Fenyö
authors.forename: G
authors.initials: G
authors.lastname: Lindberg
authors.forename: P
authors.initials: P
authors.lastname: Blind
authors.forename: L
authors.initials: L
authors.lastname: Enochsson
authors.forename: A
authors.initials: A
authors.lastname: Oberg
mesh_terms: D000208:Acute Disease; D001064:Appendicitis / Q000175:diagnosis*; D003661:Decision Support Techniques; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012372:ROC Curve