title: The effect of phenolic compounds of poplar leaves extract on cutaneous angiogenesis reaction induced in mice by human mononuclear leukocytes.
abstract: The influence of ether fraction of water-soluble extract of poplar leaves (Populus nigra L.) and nine phenolic acids (cinnamic and benzoic acids derivatives) on human mononuclear (MNL) leukocytes angiogenic activity was studied. Ether fraction, containing mainly phenolic acids, increased cutaneous angiogenesis induced in mice by human MNL isolated from the blood of healthy donors. Increase of angiogenic activity was also observed in case of caffeic, gallic, salicylic, ferulic and gentisic acids. Isovanillic, protocatechuic and p-hydroxybenzoic acids did not influence this parameter.
authors.affiliation: Department of Pharmacognosy, School of Medicine, Warsaw, Poland.
authors.forename: G
authors.initials: G
authors.lastname: Glinkowska
authors.forename: B
authors.initials: B
authors.lastname: Bałan
authors.forename: E
authors.initials: E
authors.lastname: Sommer
authors.forename: U
authors.initials: U
authors.lastname: Demkow
authors.forename: I
authors.initials: I
authors.lastname: Sokolnicka
authors.forename: H
authors.initials: H
authors.lastname: Strzelecka
authors.forename: E
authors.initials: E
authors.lastname: Skopińska-Rózewska
mesh_terms: D000818:Animals; D006801:Humans; D007962:Leukocytes / Q000187:drug effects; D051379:Mice; D008807:Mice, Inbred BALB C; D009389:Neovascularization, Pathologic / Q000188:drug therapy* / Q000209:etiology; D010636:Phenols / Q000494:pharmacology*; D010936:Plant Extracts / Q000494:pharmacology; D012867:Skin / Q000098:blood supply*; D014197:Trees
chemical_list: D010636:Phenols; D010936:Plant Extracts