The rise of human in vivo NMR spectroscopy.
NMR spectroscopy and NMR imaging with magnetic field gradients make strange bedfellows, the requirements for one seemingly ruling out the other for human applications. Nevertheless, their stories are intertwined; the advent of high field imaging systems arose because of the desire for human spectroscopy. Localized spectroscopy is possible because of NMR imaging. Both have links to physics at Nottingham, at least in the personalized account that follows. Today, virtually all NMR spectroscopy experiments can be conceived with a localized in vivo spectroscopy counterpart.
Bottomley
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PA
Department of Radiology, Johns Hopkins University, Baltimore, MD 21287-0843, USA. bottoml@mri.jhu.edu
D000818:Animals; D049673:History, 20th Century; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000266:history*