title: Occupational asthma due to porcine pancreatic amylase.
abstract: A case of occupational asthma in a 41 year old histopathology laboratory technician attributable to a powder preparation of the porcine pancreatic enzyme amylase is reported. The diagnosis was confirmed by a double blind, placebo controlled, inhalation challenge study which showed immediate and late asthmatic reactions associated with a significant increase in airway responsiveness to methacholine.
authors.affiliation: Department of Respiratory Medicine, Royal Victoria Infirmary, University of Newcastle upon Tyne.
authors.forename: T C
authors.initials: TC
authors.lastname: Aiken
authors.forename: R
authors.initials: R
authors.lastname: Ward
authors.forename: E T
authors.initials: ET
authors.lastname: Peel
authors.forename: D J
authors.initials: DJ
authors.lastname: Hendrick
mesh_terms: D000328:Adult; D000681:Amylases / Q000009:adverse effects*; D000818:Animals; D001249:Asthma / Q000139:chemically induced*; D001985:Bronchial Provocation Tests; D004311:Double-Blind Method; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D017056:Medical Laboratory Personnel; D009784:Occupational Diseases / Q000139:chemically induced*; D010919:Placebos; D013552:Swine
chemical_list: D010919:Placebos; D000681:Amylases