p53 gene mutation: software and database.
A large number of different mutations in the p53 tumor suppressor gene have been identified in all types of cancer. As of October, 1997, this database (http:// perso.curie.fr/tsoussi ) contained >7500 mutations. Such a substantial increase since our previous reports should enable epidemiological analyses which were not previously possible. In order to analyse these new data, the UMD software has been improved. A new Web version of the UMD software enables online analysis of the database. The present report describes various improvements since the last release of the database.
Béroud
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C
Hôpital Necker Enfants Malades, U383 INSERM, Paris, France.
Soussi
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T
D000818:Animals; D003195:Computer Communication Networks; D004252:DNA Mutational Analysis; D016208:Databases, Factual; D016158:Genes, p53; D006801:Humans; D016247:Information Storage and Retrieval; D009154:Mutation; D012984:Software