Lymphocyte homeostasis.
B- and T-lymphocyte populations have an independent homeostatic regulation of resting (B and T) and activated (B) or memory (T) cell compartments. This organization may provide an efficient mechanism to ensure simultaneously a first natural barrier of protection against common pathogens, the maintenance of immunological T-cell memory and a reservoir of repertoire diversity capable of dealing with new antigenic challenges.
Tanchot
C
C
INSERM U345, Institut Necker, 156 Rue Vaugirard, Paris, 75015, France.
Rosado
M M
MM
Agenes
F
F
Freitas
A A
AA
Rocha
B
B
D000818:Animals; D001402:B-Lymphocytes / Q000276:immunology*; D001854:Bone Marrow Cells; D006706:Homeostasis; D007156:Immunologic Memory; D008213:Lymphocyte Activation; D051379:Mice; D018448:Models, Immunological; D013601:T-Lymphocytes / Q000276:immunology*; D013950:Thymus Gland