Villous adenoma of the bladder.
Villous adenomas of the bladder are rare tumors and up to now they have not been seen to undergo malignant transformation. We report a case of villous adenoma of the bladder with areas of adenocarcinoma in a 72-year-old man. We describe all the morphological, histochemical and immunohistochemical features characterizing this tumor. We recommend adequate pathological sampling and a thorough follow-up of patients with villous adenoma. The prognosis and the behaviour of these adenomatous papillary lesions, morphologically similar to colonic adenomas, in the bladder is unclear. We report a case with focal area of adenocarcinoma and review the literature.
Tripodi
S A
SA
Department of Pathology, University of Siena.
Laurini
L
L
Presenti
L
L
Brunettini
C
C
Boncompagni
G
G
Messina
M
M
D'Agata
A
A
Del Vecchio
M T
MT
D000230:Adenocarcinoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D018253:Adenoma, Villous / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D018450:Disease Progression; D006417:Hematuria / Q000209:etiology; D006801:Humans; D008297:Male; D008679:Metaplasia; D009363:Neoplasm Proteins / Q000032:analysis; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D019459:Urothelium / Q000473:pathology
D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins