Localized unilateral periorbital edema induced by aspirin.
BACKGROUND
Aspirin intolerance manifested as bronchospasm or urticaria/angioedema has been observed since the beginning of this century.


OBJECTIVE
To report a novel case of intolerance to aspirin ingestion.


METHODS
Case report; routine skin testing; pulmonary function testing; aspirin challenge.


RESULTS
A 30-year-old man with a history of left ocular trauma at the age of 10 noted a 3-year history of left periorbital angioedema after aspirin but not other nonsteroidal anti-inflammatory drugs. Incremental oral aspirin challenge resulted in this unilateral symptomatology at a dose of 673 mg.


CONCLUSIONS
To the best of our knowledge, this is the first reported case of unilateral periorbital edema following aspirin ingestion.
Price
K S
KS
Department of Medicine, Montreal General Hospital, McGill University.
Thomson
D M
DM
D000328:Adult; D000799:Angioedema / Q000139:chemically induced*; D001241:Aspirin / Q000009:adverse effects*; D004361:Drug Tolerance / Q000276:immunology / Q000502:physiology; D006801:Humans; D008297:Male; D009916:Orbital Diseases / Q000139:chemically induced*
D001241:Aspirin