title: Intermittent pneumatic sequential compression (ISC) of the lower extremities prevents venous stasis during laparoscopic cholecystectomy. A prospective randomized study.
abstract: BACKGROUND
  Fifty patients were included in a prospective randomized trial to evaluate the efficacy of intermittent sequential compression (ISC) of the lower extremities in preventing venous stasis during laparoscopic cholecystectomy.
  
  
  METHODS
  We treated 25 patients with (+ISC) and 25 without (-ISC) intermittent sequential compression. Peak flow velocity (PFV) and cross-sectional area (CSA) of the right femoral vein were measured by Doppler ultrasound before, during, and after capnopneumoperitoneum with 14 mm Hg.
  
  
  RESULTS
  PFV was 26.4 (8.4) cm/s and CSA was 1.03 (0.23) cm2 before pneumoperitoneum was induced. During abdominal insufflation, PFV decreased to 61% of the baseline value in the (-ISC) group but remained unchanged in the (+ISC) group (t = 5.17, df = 42.8, p < 0.01). CSA was 1.06 (0.22) cm2 before insufflation. It increased to 118% of the baseline in the (-ISC) group and to 108% in the (+ISC) group (t = -1.55, df = 47.1, p = 0.13). PFV and CSA returned to baseline values within 5 min after abdominal desufflation.
  
  
  CONCLUSIONS
  ISC effectively neutralizes venous stasis during laparoscopic surgery and may decrease the risk of post-operative thromboembolic complication. Therefore, it is recommended for all prolonged laparoscopic procedures.
authors.affiliation: Department of General Surgery, Charité, Medical Faculty of the Humboldt University, Berlin, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Schwenk
authors.forename: B
authors.initials: B
authors.lastname: Böhm
authors.forename: A
authors.initials: A
authors.lastname: Fügener
authors.forename: J M
authors.initials: JM
authors.lastname: Müller
mesh_terms: D000328:Adult; D001458:Bandages; D001783:Blood Flow Velocity; D017081:Cholecystectomy, Laparoscopic / Q000379:methods*; D015908:Counterpulsation; D005069:Evaluation Studies as Topic; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012039:Regional Blood Flow; D013924:Thrombophlebitis / Q000517:prevention & control*