[Galactorrhea].
Galactorrhea syndromes are mainly caused by hyperprolactinemia, which has been defined by the basal prolactin level more than 15 ng/ml. However, normoprolactinemia can not be proved only by the basal prolactin level less than 15 ng/ml, which required the assessment of prolactin secreting capacity. Occulted hyperprolactinemia has be well known as the same syndrome as hyperprolactinemia, which shows basal prolactin level less than 15 ng/ml and the exceed response of prolactin to prolactin secreting stimulation like as thyroid releasing hormone. Women with occulted hyperprolactinemiais show temporary and intermitted hyperprolactincmia responding to a lot of atimulous states like as stress, sleep or elevated E2 level, which resulted in galactrrhea, menstrual disturbances or infertility. The elevated prolactin not only suppress the pituitary ganadotropin secretion, but also disturb follicular development and luteal function in the ovary. Dopamine agonists, bromocriptine and teruguride an usually indicate in the treatment of hyperptolactinemia and have brought the good results.
Iino
Y
Y
Department of Gynecology and Obsterics, Teikyo University School of Medicine.
Mori
H
H
D000328:Adult; D005260:Female; D005687:Galactorrhea / Q000209:etiology*; D006801:Humans; D006966:Hyperprolactinemia / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy