Flow extraction spectrophotometric method for the determination of diclofenac sodium in pharmaceutical preparations.
The spectrophotometric determination of trace amounts of diclofenac was carried out by liquid-liquid extraction using acridine yellow with a flow system. The determination of diclofenac sodium in the range of 3-80 micrograms ml-1 was possible with a sampling frequency of 40 samples h-1. The method was satisfactorily applied to the determination of diclofenac in pharmaceutical preparations.
Pérez-Ruiz
T
T
Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, Spain.
Martínez-Lozano
C
C
Sanz
A
A
San Miguel
M T
MT
D000609:Aminoacridines; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000032:analysis*; D004008:Diclofenac / Q000032:analysis*; D017022:Flow Injection Analysis / Q000379:methods*; D005456:Fluorescent Dyes; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D013053:Spectrophotometry / Q000379:methods*
D000609:Aminoacridines; D000894:Anti-Inflammatory Agents, Non-Steroidal; D005456:Fluorescent Dyes; D004364:Pharmaceutical Preparations; D004008:Diclofenac; C025902:acridine yellow