title: Functional state of segmental motoneurons in Wilson-Konovalov hepatocerebral dystrophy.
abstract: Stimulatory electromyography was used to investigate 12 patients, and chronaximetric investigations were performed in 18. Peak H-potential amplitudes indicated reductions in reflex excitability in the motoneuron pool. The stimulus size required for inducing threshold H-reflexes demonstrated a high level of reflex excitability among those alpha-motoneurons probably involved in generating hyperkinesia. Motor response parameters showed the direct electrical excitability of motor units to be elevated. Changes in H-reflex and M-response parameters demonstrated functional rearrangement of the movement analyzer after stereotaxic surgery. The functional states of the alpha- and gamma-systems are discussed.
authors.affiliation: Department of Neurological Diseases and Neurosurgery, I. P. Pavlov Russian Medical University.
authors.forename: A S
authors.initials: AS
authors.lastname: Starikov
mesh_terms: D000293:Adolescent; D000328:Adult; D002907:Chronaxy; D004576:Electromyography; D006181:H-Reflex / Q000502:physiology; D006527:Hepatolenticular Degeneration / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D006948:Hyperkinesis / Q000503:physiopathology; D009046:Motor Neurons / Q000502:physiology*; D009047:Motor Neurons, Gamma / Q000502:physiology; D014202:Tremor / Q000503:physiopathology