Solvent-induced toxic encephalopathy: electrophysiological data in relation to neuropsychological findings.
Male subjects with type 2A (n = 12) and 2B (n = 12) solvent-induced toxic encephalopathy and a reference group of healthy men (n = 12) without previous solvent exposure were studied using quantitative EEG and event-related potentials from an odd-ball and a dual-task paradigm. Subjects with toxic encephalopathy of types 2A and 2B showed markedly lower P300 amplitudes than did controls in both paradigms. In the relatively complex dual-task setting, subjects with 2A and 2B showed lower signal detection than did controls.
Lindgren
M
M
Department of Clinical Neuroscience, Lund University, Sweden.
Osterberg
K
K
Orbaek
P
P
Rosén
I
I
D001927:Brain Diseases / Q000139:chemically induced* / Q000523:psychology*; D004569:Electroencephalography; D004594:Electrophysiology; D018913:Event-Related Potentials, P300; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D016273:Occupational Exposure / Q000009:adverse effects*; D011597:Psychomotor Performance / Q000502:physiology; D012997:Solvents
D012997:Solvents