title: Causes and mechanisms of cerebellar infarction in young patients.
abstract: OBJECTIVE
  The incidence of cerebellar infarction in a series of patients with stroke is approximately 1.5%. The average patient age in most reported series is 62 years. The most common etiologies in this age group are atherosclerosis and cardiac embolism. The aim of this study was to determine the causes and mechanisms of cerebellar infarction in patients younger than 40 years.
  
  
  METHODS
  We analyzed retrospectively the clinical and radiological data from 21 men and 16 women with cerebellar infarction admitted to our hospital from January 1986 to December 1996. The patients had been studied extensively to determine the etiology of the cerebellar infarction.
  
  
  RESULTS
  In the 37 patients (mean age, 30 years), 29 infarcts were limited to one territory (15 in the posteroinferior cerebellar artery [PICA]; 14 in the superior cerebellar artery); 8 had nonterritorial infarctions. The most common stroke mechanisms in each territory were as follows: PICA: nonatherosclerotic vasculopathic (67%), cardioembolic (20%), and hematologic and cryptogenic (each 7%); superior cerebellar artery: cardioembolic (42%), cryptogenic (31%), migrainous (21%), and nonatherosclerotic vasculopathic and hematologic (each 7%); and mixed territory: nonatherosclerotic vasculopathic (50%), cryptogenic (25%), cardioembolic (12%), and hematologic (12%).
  
  
  CONCLUSIONS
  The most common mechanism of cerebellar infarctions was arterial occlusion as a result of intracranial vertebral artery dissection (40%), mainly with PICA involvement. Embolism from a cardiac source resulted primarily from patent foramen ovale and rheumatic valvular disease. Hematologic disturbances and migraine were responsible for a few cases.
authors.affiliation: Stroke Clinic, Instituto Nacional de Neurologia y Neurocirugía, Manuel Velasco Suárez, Mexico City, Mexico.
authors.forename: F
authors.initials: F
authors.lastname: Barinagarrementeria
authors.forename: L E
authors.initials: LE
authors.lastname: Amaya
authors.forename: C
authors.initials: C
authors.lastname: Cantú
mesh_terms: D000293:Adolescent; D000328:Adult; D000784:Aortic Dissection / Q000150:complications; D002526:Cerebellar Diseases / Q000209:etiology* / Q000503:physiopathology*; D002544:Cerebral Infarction / Q000209:etiology* / Q000503:physiopathology*; D003327:Coronary Disease / Q000150:complications; D004617:Embolism / Q000150:complications; D005260:Female; D006402:Hematologic Diseases / Q000150:complications; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications; D008297:Male; D008881:Migraine Disorders / Q000150:complications; D012189:Retrospective Studies; D014711:Vertebral Artery