title: Solvent-induced toxic encephalopathy: electrophysiological data in relation to neuropsychological findings.
abstract: Male subjects with type 2A (n = 12) and 2B (n = 12) solvent-induced toxic encephalopathy and a reference group of healthy men (n = 12) without previous solvent exposure were studied using quantitative EEG and event-related potentials from an odd-ball and a dual-task paradigm. Subjects with toxic encephalopathy of types 2A and 2B showed markedly lower P300 amplitudes than did controls in both paradigms. In the relatively complex dual-task setting, subjects with 2A and 2B showed lower signal detection than did controls.
authors.affiliation: Department of Clinical Neuroscience, Lund University, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Lindgren
authors.forename: K
authors.initials: K
authors.lastname: Osterberg
authors.forename: P
authors.initials: P
authors.lastname: Orbaek
authors.forename: I
authors.initials: I
authors.lastname: Rosén
mesh_terms: D001927:Brain Diseases / Q000139:chemically induced* / Q000523:psychology*; D004569:Electroencephalography; D004594:Electrophysiology; D018913:Event-Related Potentials, P300; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D016273:Occupational Exposure / Q000009:adverse effects*; D011597:Psychomotor Performance / Q000502:physiology; D012997:Solvents
chemical_list: D012997:Solvents