Pharmacology of fluticasone propionate.
Fluticasone propionate is a novel inhaled corticosteroid which has the interesting properties of a high activity combined with low gastrointestinal absorption and rapid liver metabolism. On theoretical grounds, this drug might be expected to serve as a good antiinflammatory agent in asthma, while at the same time causing minimal systemic side effects.
Sastre
J
J
Allergy Department, Jiménez Díaz Foundation, Autonomous University of Madrid, Spain.
D000280:Administration, Inhalation; D000730:Androstadienes / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D000818:Animals; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D001249:Asthma / Q000188:drug therapy; D001682:Biological Availability; D000068298:Fluticasone; D006801:Humans; D008168:Lung / Q000378:metabolism
D000730:Androstadienes; D018927:Anti-Asthmatic Agents; D000068298:Fluticasone