title: [Acute life threatening catatonia--clinical significance and therapeutic possibilities].
abstract: Malignant catatonia, associated with different somatic and psychiatric disorders, is a rare, life-threatening syndrome. Immediate recognition and adequate treatment are essential and may be life-saving. We describe a case of malignant catatonia and discuss the clinical implications. Additionally, we review the recent literature regarding epidemiology, nosology, current pathophysiological concepts, differential diagnosis, and treatment recommendations.
authors.affiliation: Psychiatrische Universitätsklinik Zürich.
authors.forename: R
authors.initials: R
authors.lastname: Bridler
authors.forename: D
authors.initials: D
authors.lastname: Hell
mesh_terms: D000328:Adult; D001712:Biperiden / Q000008:administration & dosage; D002389:Catatonia / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D003006:Clopenthixol / Q000008:administration & dosage; D003024:Clozapine / Q000008:administration & dosage; D003937:Diagnosis, Differential; D003975:Diazepam / Q000008:administration & dosage; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D012562:Schizophrenia, Disorganized / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D001712:Biperiden; D003006:Clopenthixol; D003024:Clozapine; D003975:Diazepam