The combination of oral acitretin and bath PUVA for the treatment of severe psoriasis.
We report four patients with severe erythrodermic, pustular psoriasis, or plaque-type psoriasis, who were treated with a combination of acitretin and bath PUVA. After 4 weeks out-patient treatment, the psoriasis in all patients had improved by > or = 90%. No patient had relapsed when reviewed at 3 months. No significant side-effects were seen with the combined retinoid/bath PUVA treatment. Acitretin and bath PUVA may be safely combined for the treatment of severe psoriasis.
Muchenberger
S
S
Department of Dermatology, University Medical Centre, Freiburg, Germany.
Schöpf
E
E
Simon
J C
JC
D017255:Acitretin / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D004359:Drug Therapy, Combination; D005500:Follow-Up Studies; D006801:Humans; D007641:Keratolytic Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011701:PUVA Therapy; D011565:Psoriasis / Q000188:drug therapy* / Q000473:pathology
D007641:Keratolytic Agents; D017255:Acitretin