Polyarteritis nodosa and the antiphospholipid syndrome.
We describe a case of classical polyarteritis nodosa (PAN) with visceral aneurysms presenting with renal infarction and hypertension. The female patient also had all the laboratory features of the antiphospholipid syndrome (APS) and 2 months into her illness developed a large iliofemoral thrombosis. She responded well to immunosuppressive therapy and anti-coagulation. Repeat arteriogram showed regression of the visceral aneurysms. The link between PAN and APS, and the therapeutic dilemma posed by this association, are discussed.
Dasgupta
B
B
Department of Rheumatology, Southend General Hospital, Westcliff-on-Sea, Essex.
Almond
M K
MK
Tanqueray
A
A
D000783:Aneurysm / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology; D016736:Antiphospholipid Syndrome / Q000150:complications*; D001027:Aortography; D005260:Female; D005268:Femoral Vein / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D006977:Hypertension, Renal / Q000209:etiology; D007084:Iliac Vein / Q000000981:diagnostic imaging / Q000473:pathology; D007238:Infarction / Q000209:etiology; D007668:Kidney / Q000098:blood supply; D008875:Middle Aged; D010146:Pain / Q000209:etiology; D010488:Polyarteritis Nodosa / Q000150:complications*; D012077:Renal Artery / Q000000981:diagnostic imaging / Q000473:pathology; D013924:Thrombophlebitis / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology