title: Chronic noninvasive ventilation in obstructive airways disease.
abstract: Early experience with noninvasive ventilation in patients with chronic obstructive pulmonary disease was largely unsuccessful, with no benefit over long-term oxygen therapy. Nasal positive pressure ventilation, however, produces improvements in arterial blood gases, nocturnal-hypoventilation, and quality of life. Experience with nasal ventilation in other obstructive airways diseases, such as bronchiectasis and cystic fibrosis, is limited and less favorable.
authors.affiliation: Respiratory Care Unit, London Chest Hospital, United Kingdom.
authors.forename: J A
authors.initials: JA
authors.lastname: Wedzicha
mesh_terms: D001987:Bronchiectasis / Q000628:therapy; D003550:Cystic Fibrosis / Q000628:therapy; D006801:Humans; D007040:Hypoventilation / Q000209:etiology / Q000628:therapy; D007385:Intermittent Positive-Pressure Ventilation / Q000295:instrumentation / Q000379:methods; D008173:Lung Diseases, Obstructive / Q000150:complications / Q000628:therapy*; D012121:Respiration, Artificial / Q000379:methods*; D016896:Treatment Outcome