title: Sensitivity of computed tomography in detecting local recurrence of prostatic carcinoma following radical prostatectomy.
abstract: The aim of this study was to evaluate CT imaging in the post-operative follow-up and in the detection of recurrence after radical prostatectomy in cases of prostatic carcinoma. In over 500 patients undergoing radical prostatectomy for prostatic carcinoma, 22 cases with local recurrence were found. CT examinations of the pelvis were retrospectively evaluated in these patients. Local recurrence was detected by PSA uptake and confirmed by transrectal ultrasound (TRUS) in combination with guided biopsy. In 22 cases of confirmed local recurrence, positive results on CT were found in eight patients (36%) and negative results in nine patients (41%). In the remaining five cases (23%), no distinction could be made between scar and local recurrence. All cases definitively classified as recurrent tumour disease showed a soft tissue mass of 2 cm or more. CT sensitivity in local recurrence of prostatic carcinoma after surgery is low. Even in a very careful follow-up, the understaging would be up to 41%. In comparison, PSA, TRUS and needle biopsy are the methods of choice and are superior to CT imaging. Based on these results, there would be no reason for including pelvic CT examinations in the follow-up of prostatic carcinoma after radical prostatectomy.
authors.affiliation: Department of Radiology, University of Ulm, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Krämer
authors.forename: J
authors.initials: J
authors.lastname: Görich
authors.forename: H W
authors.initials: HW
authors.lastname: Gottfried
authors.forename: P
authors.initials: P
authors.lastname: Riska
authors.forename: A J
authors.initials: AJ
authors.lastname: Aschoff
authors.forename: N
authors.initials: N
authors.lastname: Rilinger
authors.forename: H J
authors.initials: HJ
authors.lastname: Brambs
authors.forename: R
authors.initials: R
authors.lastname: Sokiranski
mesh_terms: D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D011184:Postoperative Period; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography