title: Flow extraction spectrophotometric method for the determination of diclofenac sodium in pharmaceutical preparations.
abstract: The spectrophotometric determination of trace amounts of diclofenac was carried out by liquid-liquid extraction using acridine yellow with a flow system. The determination of diclofenac sodium in the range of 3-80 micrograms ml-1 was possible with a sampling frequency of 40 samples h-1. The method was satisfactorily applied to the determination of diclofenac in pharmaceutical preparations.
authors.affiliation: Department of Analytical Chemistry, Faculty of Chemistry, University of Murcia, Spain.
authors.forename: T
authors.initials: T
authors.lastname: Pérez-Ruiz
authors.forename: C
authors.initials: C
authors.lastname: Martínez-Lozano
authors.forename: A
authors.initials: A
authors.lastname: Sanz
authors.forename: M T
authors.initials: MT
authors.lastname: San Miguel
mesh_terms: D000609:Aminoacridines; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000032:analysis*; D004008:Diclofenac / Q000032:analysis*; D017022:Flow Injection Analysis / Q000379:methods*; D005456:Fluorescent Dyes; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D013053:Spectrophotometry / Q000379:methods*
chemical_list: D000609:Aminoacridines; D000894:Anti-Inflammatory Agents, Non-Steroidal; D005456:Fluorescent Dyes; D004364:Pharmaceutical Preparations; D004008:Diclofenac; C025902:acridine yellow