title: Mechanisms of limited maximum coronary flow in severe single-vessel coronary artery disease in humans due to vertical steal.
abstract: We evaluated the usefulness of a decrease in the average peak velocity from 4 to 10 minutes after infusion of dipyridamole for detecting myocardial ischemia in 50 patients, including patients with a prior myocardial infarction. The decrease in the average peak velocity from 4 to 10 minutes associated with vertical steal and combined with a coronary flow reserve of < 1.6 had a high predictive value for myocardial ischemia in patients with or without prior myocardial infarction.
authors.affiliation: First Department of Internal Medicine, Faculty of Medicine, Kagoshima University, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Hamasaki
authors.forename: S
authors.initials: S
authors.lastname: Arima
authors.forename: N
authors.initials: N
authors.lastname: Fukumoto
authors.forename: T
authors.initials: T
authors.lastname: Yamaguchi
authors.forename: F
authors.initials: F
authors.lastname: Nakano
authors.forename: M
authors.initials: M
authors.lastname: Kamekou
authors.forename: K
authors.initials: K
authors.lastname: Kihara
authors.forename: H
authors.initials: H
authors.lastname: Shono
authors.forename: S
authors.initials: S
authors.lastname: Nakao
authors.forename: H
authors.initials: H
authors.lastname: Tanaka
mesh_terms: D000368:Aged; D001783:Blood Flow Velocity / Q000187:drug effects; D003326:Coronary Circulation; D004176:Dipyridamole / Q000494:pharmacology; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology; D017202:Myocardial Ischemia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D013794:Thallium Radioisotopes; D014665:Vasodilator Agents / Q000494:pharmacology
chemical_list: D013794:Thallium Radioisotopes; D014665:Vasodilator Agents; D004176:Dipyridamole