title: Bipolar affective disorder associated with Klinefelter's syndrome--a case report.
abstract: Several cytogenetic surveys and literature reviews have suggested a possible association between Klinefelter's syndrome and bipolar illness. We describe a manic patient with Klinefelter's syndrome who was treated successfully with lithium. Our patient represents the 32nd reported case of bipolar disorder in an individual with a known chromosomal abnormality, the 15th with Klinefelter's syndrome, and the 11th with a karyotype of 47XXY.
authors.affiliation: Department of Psychiatry, Faculty of Medicine, Karadeniz Technical University, Trabzon, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Bekaroglu
authors.forename: C
authors.initials: C
authors.lastname: Soylu
authors.forename: N
authors.initials: N
authors.lastname: Soylu
authors.forename: M
authors.initials: M
authors.lastname: Bilici
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000235:genetics*; D008040:Genetic Linkage / Q000235:genetics; D006801:Humans; D007621:Karyotyping; D007713:Klinefelter Syndrome / Q000235:genetics*; D008297:Male; D014960:X Chromosome