Subcutaneous phaeohyphomycosis caused by Phoma cava. Report of a case and review of the literature.
We report a case of subcutaneous phaeohyphomycosis observed in a male patient presenting pulmonary sarcoidosis and submitted to corticosteroid treatment. He presented nodular erythematous-violaceous skin lesions in the dorsum of the right hand. Histopathological examination of the biopsied lesion revealed dematiaceous hyphae and yeast-like cells, with a granulomatous tissual reaction. The isolated fungus was identified as Phoma cava. A review of the literature on fungal infection caused by different Phoma species, is presented. The patient healed after therapy with amphotericin B. followed by itraconazole.
Zaitz
C
C
Faculty of Medical Sciences, Santa Casa de São Paulo, Brasil.
Heins-Vaccari
E M
EM
de Freitas
R S
RS
Arriagada
G L
GL
Ruiz
L
L
Totoli
S A
SA
Marques
A C
AC
Rezze
G G
GG
Müller
H
H
Valente
N S
NS
Lacaz
C da S
Cda S
D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D003904:Mitosporic Fungi / Q000302:isolation & purification; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology
D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B