title: [The effect of a paravertebral novocaine block on acid formation in the stomach].
abstract: The dependence of acid-formation in the stomach on the blockade of sympathetic innervation of the acid-formation area was investigated in 38 patients in whom the paravertebral novocaine blockade was made at the ThVII-ThIX level in order to cup off the pain syndrome. The control group included 7 patients without diseases of the organs of the hepato-pancreatico-duodenal zone. This blockade was found to sharply increase the basal acid-formation in healthy people. In patients with the high acid-formation it leads to greater elevation of acidity. It was shown that the disturbed functional balance between two parts of the vegetative nervous system responsible for the acid-formation function of the stomach was one of the causes of higher acid formation in patients with peptic ulcer of the gastroenterostomy and with chronic ulcer of the duodenum. It seems to be reasonable to investigate disturbances of the function of sympathetic innervation of the acid-formation area of the stomach for determining the optimum volume of surgical interventions in such patients.
authors.forename: A A
authors.initials: AA
authors.lastname: Kurygin
authors.forename: A N
authors.initials: AN
authors.lastname: Voĭtsitskiĭ
authors.forename: M A
authors.initials: MA
authors.lastname: Nikulin
authors.forename: N N
authors.initials: NN
authors.lastname: Lebedev
mesh_terms: D000779:Anesthetics, Local; D001340:Autonomic Nerve Block / Q000379:methods*; D002908:Chronic Disease; D004381:Duodenal Ulcer / Q000503:physiopathology; D005744:Gastric Acid / Q000378:metabolism*; D006801:Humans; D011343:Procaine; D013126:Spinal Nerve Roots / Q000000981:diagnostic imaging; D013276:Stomach Ulcer / Q000503:physiopathology; D013904:Thoracic Vertebrae; D014057:Tomography, X-Ray Computed
chemical_list: D000779:Anesthetics, Local; D011343:Procaine