title: Povidone-iodine in antisepsis--state of the art.
abstract: The natural element iodine has been used for more than 150 years to prevent infection and treat wounds. Yet only due to the development of iodophors has it become possible to use this highly efficient microbicide in a wide range of medical applications. The antimicrobial spectrum is universal. Its efficiency against clinically and epidemiologically significant new pathogens, such as methicillin-resistant Staphylococcus aureus and Enterococcus sp. has also been validated. No development of resistance has been determined. New data are also available on the excellent local tolerability of Betaisodona (povidone-iodine) preparations. On these grounds, a number of clinical fields exist in prophylaxis and therapy, for either once only or repeated applications: the disinfection of hands and skin, mucosa antisepsis, intra- and postoperative wound treatment, therapy of skin infections, burns and chronic wounds.
authors.affiliation: Mundipharma GmbH, Limburg, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Fleischer
authors.forename: K
authors.initials: K
authors.lastname: Reimer
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D000985:Antisepsis; D001424:Bacterial Infections / Q000188:drug therapy / Q000517:prevention & control; D002056:Burns / Q000188:drug therapy; D002908:Chronic Disease; D016983:Enterococcus / Q000187:drug effects; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy; D006225:Hand / Q000382:microbiology; D006801:Humans; D007430:Intraoperative Care; D007466:Iodophors / Q000627:therapeutic use*; D016106:Methicillin Resistance; D009092:Mucous Membrane / Q000382:microbiology; D011182:Postoperative Care; D011206:Povidone-Iodine / Q000627:therapeutic use*; D012867:Skin / Q000293:injuries / Q000382:microbiology; D012874:Skin Diseases, Infectious / Q000188:drug therapy; D013203:Staphylococcal Infections / Q000188:drug therapy; D013211:Staphylococcus aureus / Q000187:drug effects; D014946:Wound Infection / Q000188:drug therapy / Q000517:prevention & control
chemical_list: D000891:Anti-Infective Agents, Local; D007466:Iodophors; D011206:Povidone-Iodine