Prenatal fluoride for growth and development: Part X.
Examinations of prenatal fluoride supplemented (PNF) teeth in an animal model and in a five-month human fetus find these teeth to be more developed than the non-supplemented controls. The fact that PNF allows teeth to develop to their full potential suggests that PNF could be an essential nutrient for the entire human and this could be demonstrated most easily during rapid fetal growth. A review of the recent literature, including trials by NIH and The World Health Organization, provide evidence that fluoride (F) does allow the fetus to grow and develop to its full potential. The authors conclude that PNF must be supplied in at least a 2 mg/day pulse dose, and then F must be given from shortly after birth in a daily amount appropriate for the weight of the child with some consideration for the amount of F water utilized.
Glenn
F B
FB
Children's Dental Research Society, Miami, FL, USA.
Glenn
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WD
Burdi
A R
AR
D000565:Ameloblasts / Q000166:cytology; D000818:Animals; D001835:Body Weight; D016022:Case-Control Studies; D006224:Cricetinae; D003743:Dental Enamel / Q000196:embryology; D003771:Dental Papilla / Q000196:embryology; D019587:Dietary Supplements; D004195:Disease Models, Animal; D005314:Embryonic and Fetal Development / Q000187:drug effects*; D004847:Epithelial Cells / Q000166:cytology; D005152:Facial Muscles / Q000196:embryology; D005260:Female; D005457:Fluoridation; D005459:Fluorides / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007180:Incisor / Q000196:embryology; D008334:Mandible / Q000196:embryology; D009804:Odontoblasts / Q000166:cytology; D009805:Odontogenesis / Q000187:drug effects; D011247:Pregnancy
D005459:Fluorides