Use of integral and differential methods for the determination of L-dopa in pure form and pharmaceutical preparations.
A new simple and selective kinetic method for the determination of L-dopa, using differential and integral methods, is described. The spectrophotometric measurements were recorded by measuring the increase in absorbance at 300 nm. The concentration range was valid from 5-35 ppm. The complex ratio showed a (1:2) of L-dopa with respect to sodium hydroxide, with formation constant 5.06 x 10(6) and molar absorptivity of 3.85 x 10(3) l mol-1 cm-1.
Helaleh
M I
MI
Department of Chemistry, Aligarh Muslim University, India.
Rahman
N
N
Jamhour
R M
RM
Abu Nameh
E S
ES
D000978:Antiparkinson Agents / Q000032:analysis*; D006863:Hydrogen-Ion Concentration; D007700:Kinetics; D007980:Levodopa / Q000032:analysis*; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D012972:Sodium Hydroxide / Q000737:chemistry; D013056:Spectrophotometry, Ultraviolet / Q000379:methods*; D013696:Temperature
D000978:Antiparkinson Agents; D004364:Pharmaceutical Preparations; D007980:Levodopa; D012972:Sodium Hydroxide