Value of the electrocardiogram in determining cardiac events and mortality in myotonic dystrophy.
Electrocardiograms were recorded at baseline and regular intervals in 53 patients with myotonic dystrophy who were followed for a mean of 6.3 +/- 4.0 years. Patients with cardiac events had a significantly prolonged PR interval (p <0.001), a later age of onset of neuromuscular symptoms (p <0.05), and were older (p <0.005).
Colleran
J A
JA
Department of Neurology, Georgetown University Medical Center, Washington, D.C., USA.
Hawley
R J
RJ
Pinnow
E E
EE
Kokkinos
P F
PF
Fletcher
R D
RD
D000328:Adult; D016757:Death, Sudden, Cardiac; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006331:Heart Diseases / Q000175:diagnosis* / Q000401:mortality* / Q000503:physiopathology; D006801:Humans; D008297:Male; D009223:Myotonic Dystrophy / Q000401:mortality / Q000503:physiopathology*; D011237:Predictive Value of Tests; D012307:Risk Factors; D015996:Survival Rate; D013997:Time Factors