title: Homology modeling of glycosyl hydrolase family 18 enzymes and proteins.
abstract: Using state-of-the-art homology modeling methods, three-dimensional coordinates for three family 18 glycosyl hydrolases were determined. The structures for Gp39, Brp39, and chitotriosidase were computer determined using the X-ray coordinates from SmChiA. The results of the modeling efforts are assessed, and comparison of the modeled structures to other known family 18 members is made.
authors.affiliation: Department of Biochemistry and Molecular Biology, College of Medicine, Mobile, Alabama, USA.
authors.forename: N N
authors.initials: NN
authors.lastname: Aronson
authors.forename: C J
authors.initials: CJ
authors.lastname: Blanchard
authors.forename: J D
authors.initials: JD
authors.lastname: Madura
mesh_terms: D000118:Acetylglucosaminidase / Q000737:chemistry*; D000595:Amino Acid Sequence; D000818:Animals; D002688:Chitinases / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006801:Humans; D008961:Models, Structural; D008969:Molecular Sequence Data; D011487:Protein Conformation; D017386:Sequence Homology, Amino Acid
chemical_list: D002688:Chitinases; D000118:Acetylglucosaminidase