title: Magnetization transfer and spin lock MR imaging of patellar cartilage degeneration at 0.1 T.
abstract: OBJECTIVE
  To investigate magnetization transfer (MT) parameters and rotating frame relaxation time T1 rho in patellar cartilage at different levels of degeneration.
  
  
  METHODS
  Thirty cadaveric patellae were examined at 0.1 T using the time-dependent saturation-transfer MT technique and the spin lock (SL) technique. In an SL experiment, nuclear spins are locked with a radiofrequency (RF) field, and the locked nuclear magnetization relaxes along the magnetic component of the locking RF field. The specimens were divided into three groups according to the level of cartilage degeneration. MT parameters and T1 rho were measured.
  
  
  RESULTS
  The MT effect was greater in degenerated cartilage than in normal cartilage. T1 rho was longer in advanced cartilage degeneration than in intermediate cartilage degeneration.
  
  
  CONCLUSIONS
  The results suggest that more studies are needed to fully establish the value of SL imaging in cartilage degeneration.
authors.affiliation: Department of Diagnostic Radiology, Turku University Hospital, University of Turku, Finland.
authors.forename: S K
authors.initials: SK
authors.lastname: Koskinen
authors.forename: H
authors.initials: H
authors.lastname: Ylä-Outinen
authors.forename: H J
authors.initials: HJ
authors.lastname: Aho
authors.forename: M E
authors.initials: ME
authors.lastname: Komu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D001853:Bone Marrow / Q000473:pathology; D002102:Cadaver; D002357:Cartilage Diseases / Q000175:diagnosis / Q000473:pathology; D002358:Cartilage, Articular / Q000473:pathology*; D002648:Child; D019902:Chondrocytes / Q000473:pathology; D004578:Electron Spin Resonance Spectroscopy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010329:Patella / Q000473:pathology*