title: Fetal fibronectin in vaginal fluid of women in prolonged pregnancy.
abstract: The aim of this study was to determine fetal fibronectin in vaginal fluid of women in prolonged pregnancy, its relationship to a modified Bishop score and its predictiveness of delivery within 3 days. Vaginal samples were collected from 80 women at 42 weeks of gestation for the fetal fibronectin assay. A modified Bishop score was estimated. Fetal fibronectin was determined by a quantitative enzyme immunoassay. The concentration of fetal fibronectin in vaginal fluid was elevated in only 36 of the 80 women. The Bishop score and the time between sampling and delivery were not associated with an elevated fetal fibronectin (> or = 0.05 mg/l). We conclude that fetal fibronectin is not a good indicator of delivery within 3 days. The findings add to our understanding of the complexity of the etiology of postterm labor.
authors.affiliation: Department of Obstetrics and Gynecology, Sahlgrens University Hospital, University of Göteborg, Sweden.
authors.forename: A R
authors.initials: AR
authors.lastname: Goffeng
authors.forename: I
authors.initials: I
authors.lastname: Milsom
authors.forename: G
authors.initials: G
authors.lastname: Lindstedt
authors.forename: P A
authors.initials: PA
authors.lastname: Lundberg
authors.forename: B
authors.initials: B
authors.lastname: Andersch
mesh_terms: D000328:Adult; D015415:Biomarkers; D001826:Body Fluids / Q000378:metabolism; D036861:Delivery, Obstetric; D005260:Female; D005333:Fetus / Q000378:metabolism*; D005353:Fibronectins / Q000378:metabolism*; D005865:Gestational Age; D006801:Humans; D007124:Immunoenzyme Techniques; D011237:Predictive Value of Tests; D011247:Pregnancy; D011273:Pregnancy, Prolonged / Q000378:metabolism*; D014621:Vagina / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D005353:Fibronectins