title: Evaluation of tremor in aluminum production workers.
abstract: A cross-sectional study of 63 current and former aluminum potroom workers and 37 comparison workers was conducted to evaluate for evidence of neurological dysfunction, including tremor from long-term exposures to aluminum using sensitive quantitative measures of arm/hand and leg tremor. Signs of upper extremity tremor were also evaluated by neurological examination and compared with the quantitative measures of arm/hand tremor. Both arm/hand and leg tremor were measured using fatiguing test conditions, but no statistically significant differences due to exposure to aluminum were present between the potroom workers and the comparison workers. The neurological examination also showed no statistically significant differences between the groups on the evaluation of signs of tremor. These results do not support the findings of Best-Pettersen et al., who reported evidence of increased tremor in aluminum workers using the static steadiness test in the Halstead-Reitan battery. Differences between the studies that may have contributed to the contrasting results are discussed. In addition, techniques are presented for using microcomputer-controlled devices to evaluate tremor in both the visible (1-6 Hz) and nonvisible (7-18 Hz) frequencies of the tremor spectrum.
authors.affiliation: US Department of Health and Human Services, Public Health Service/Centers for Disease Control and Prevention, Cincinnati, Ohio, USA.
authors.forename: R B
authors.initials: RB
authors.lastname: Dick
authors.forename: E F
authors.initials: EF
authors.lastname: Krieg
authors.forename: M A
authors.initials: MA
authors.lastname: Sim
authors.forename: B P
authors.initials: BP
authors.lastname: Bernard
authors.forename: B T
authors.initials: BT
authors.lastname: Taylor
mesh_terms: D000535:Aluminum; D006801:Humans; D008669:Metallurgy; D016273:Occupational Exposure / Q000009:adverse effects* / Q000517:prevention & control; D014202:Tremor / Q000139:chemically induced*
chemical_list: D000535:Aluminum