title: Hyperplastic (metaplastic) polyposis of the colorectum associated with adenomas and an adenocarcinoma.
abstract: Hyperplastic (metaplastic) polyposis associated with adenoma and adenocarcinoma of the colorectum is rare. We describe a 55-year-old man with hyperplastic polyposis associated with multiple adenomas and an adenocarcinoma who underwent total colectomy. We found at least 200 polyps in the surgical specimen. Nearly all of the polyps were hyperplastic, and some were adenomas. Furthermore, some hyperplastic polyps had adenomatous areas. This indicates the transformational sequence of a hyperplastic polyp to adenoma to adenocarcinoma.
authors.affiliation: First Department of Internal Medicine, School of Medicine, Iwate Medical University, Morioka, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Orii
authors.forename: S
authors.initials: S
authors.lastname: Nakamura
authors.forename: T
authors.initials: T
authors.lastname: Sugai
authors.forename: W
authors.initials: W
authors.lastname: Habano
authors.forename: I
authors.initials: I
authors.lastname: Akasaka
authors.forename: F
authors.initials: F
authors.lastname: Nakasima
authors.forename: H
authors.initials: H
authors.lastname: Kazama
authors.forename: Y
authors.initials: Y
authors.lastname: Hasimoto
authors.forename: H
authors.initials: H
authors.lastname: Takahasi
authors.forename: M
authors.initials: M
authors.lastname: Sugawara
authors.forename: S
authors.initials: S
authors.lastname: Sato
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000236:Adenoma / Q000473:pathology*; D003111:Colonic Polyps / Q000473:pathology*; D015179:Colorectal Neoplasms / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged