Fulminant demyelinating neuropathy mimicking cerebral death.
Guillain-Barré syndrome can very rarely present with acute quadripares and cranial nerve involvement resembling a locked-in state. We describe a very unusual case of fulminant neuropathy in a child who was previously exposed to vincristine. The clinical picture resembled brain death; however, electrodiagnostic studies led to the diagnosis of a peripheral neuropathy. Serial electrodiagnostic studies and pathologic findings confirmed demyelination.
Bakshi
N
N
Department of Neurology, University of California-Davis, 95616, USA.
Maselli
R A
RA
Gospe
S M
SM
Ellis
W G
WG
McDonald
C
C
Mandler
R N
RN
D001706:Biopsy; D001926:Brain Death / Q000175:diagnosis*; D002648:Child; D019411:Clinical Laboratory Techniques; D003937:Diagnosis, Differential; D004568:Electrodiagnosis; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D011129:Polyradiculoneuropathy / Q000175:diagnosis* / Q000628:therapy; D013497:Sural Nerve / Q000473:pathology
D016756:Immunoglobulins, Intravenous