title: Fresh osteochondral allografts for post-traumatic osteochondral defects of the knee.
abstract: We used fresh small-fragment osteochondral allografts to reconstruct post-traumatic osteochondral defects in 126 knees of 123 patients with a mean age of 35 years. At a mean follow-up of 7.5 years (2 to 20), 108 knees were rated as successful (85%) and 18 had failed (15%). The factors related to failure included age over 50 years (p = 0.008), bipolar defects (p < 0.05), malaligned knees with overstressing of the grafts, and workers' compensation cases (p < 0.04). Collapse of the graft by more than 3 mm and of the joint space of more than 50% were seen more frequently in radiographs of failed grafts. Our encouraging clinical results for fresh small-fragment osteochondral allografts show that they are indicated for unipolar post-traumatic osteochondral defects of the knee in young active patients.
authors.affiliation: Mount Sinai Hospital, Toronto, Ontario, Canada.
authors.forename: M T
authors.initials: MT
authors.lastname: Ghazavi
authors.forename: K P
authors.initials: KP
authors.lastname: Pritzker
authors.forename: A M
authors.initials: AM
authors.lastname: Davis
authors.forename: A E
authors.initials: AE
authors.lastname: Gross
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001863:Bone Screws; D016025:Bone Transplantation / Q000000981:diagnostic imaging / Q000473:pathology; D002356:Cartilage / Q000637:transplantation*; D002358:Cartilage, Articular / Q000000981:diagnostic imaging / Q000293:injuries / Q000473:pathology / Q000601:surgery; D016001:Confidence Intervals; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging / Q000293:injuries / Q000473:pathology / Q000601:surgery; D005500:Follow-Up Studies; D006085:Graft Survival; D006801:Humans; D007718:Knee Injuries / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010027:Osteotomy / Q000379:methods; D010329:Patella / Q000000981:diagnostic imaging / Q000293:injuries / Q000473:pathology / Q000601:surgery; D011183:Postoperative Complications; D011859:Radiography; D013314:Stress, Mechanical; D016019:Survival Analysis; D013977:Tibia / Q000000981:diagnostic imaging / Q000293:injuries / Q000473:pathology / Q000601:surgery; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D014942:Workers' Compensation