title: Synthetic osteochondral replacement of the femoral articular surface.
abstract: We have studied damage to the tibial articular surface after replacement of the femoral surface in dogs. We inserted pairs of implants made of alumina, titanium and polyvinyl alcohol (PVA) hydrogel on titanium fibre mesh into the femoral condyles. The two hard materials caused marked pathological changes in the articular cartilage and menisci, but the hydrogel composite replacement caused minimal damage. The composite osteochondral device became rapidly attached to host bone by ingrowth into the supporting mesh. We discuss the clinical implications of the possible use of this material in articular resurfacing and joint replacement.
authors.affiliation: Kyoto University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Oka
authors.forename: Y S
authors.initials: YS
authors.lastname: Chang
authors.forename: T
authors.initials: T
authors.lastname: Nakamura
authors.forename: K
authors.initials: K
authors.lastname: Ushio
authors.forename: J
authors.initials: J
authors.lastname: Toguchida
authors.forename: H O
authors.initials: HO
authors.lastname: Gu
mesh_terms: D000537:Aluminum Oxide; D000818:Animals; D019643:Arthroplasty, Replacement; D016723:Bone Remodeling; D002358:Cartilage, Articular / Q000473:pathology; D003238:Connective Tissue / Q000473:pathology; D004285:Dogs; D005269:Femur / Q000601:surgery*; D006614:Hindlimb / Q000601:surgery; D007595:Joint Prosthesis; D008592:Menisci, Tibial / Q000473:pathology; D016348:Osseointegration; D011142:Polyvinyl Alcohol; D016062:Porosity; D011474:Prosthesis Design; D016059:Range of Motion, Articular; D013526:Surgical Mesh; D013977:Tibia / Q000473:pathology; D014025:Titanium; D016474:Weight-Bearing
chemical_list: D011142:Polyvinyl Alcohol; D014025:Titanium; D000537:Aluminum Oxide