[A new method for evaluating the rheological properties of the erythrocytes in surgical patients with endogenous intoxication].
An examination of 30 patients against the background of using both the operative and conservative methods of treatment was performed in order to study the rheological properties of blood and selection of the most informative tests for diagnosis of microcirculatory disturbances in diseases of the gastrointestinal tract and gastroduodenal area. The authors propose methods of investigation of deformability and viscosity of erythrocytes in patients with the surgical diseases in question. The methods are simple, quite handy for any surgical hospital and polyclinic laboratories. In addition to being used in investigations of the aggregative ability of erythrocytes and viscosity of the whole blood, these methods can be of use in express diagnosis of rheological disorders. The endogenous intoxication in patients with the diseases in question was found to be accompanied by deep rheological disturbances. The deformability of erythrocytes and their viscosity index which can pass ahead of the shifts in other parameters characterizing the hemocoagulative and rheological properties of blood are changed. A conclusion is drawn that the parameters of the erythrocyte deformability and viscosity can be an additional criteria of the adequacy of therapy used for patients with the diseases in question.
Bessmel'tsev
S S
SS
Tsarapkin
I M
IM
Fedorova
Z D
ZD
D000208:Acute Disease; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001660:Biliary Tract Diseases / Q000097:blood / Q000601:surgery; D004903:Erythrocyte Aggregation; D004907:Erythrocyte Deformability; D005260:Female; D018056:Hemorheology / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010182:Pancreatic Diseases / Q000097:blood / Q000601:surgery; D010437:Peptic Ulcer / Q000097:blood / Q000150:complications / Q000601:surgery; D018805:Sepsis / Q000097:blood*