[Synthesis and structure of substituted arylazo-imidazolidines and arylidenethiazolidines].
Synthesis and physico-chemical properties of four 3-benzyl or 3-(4-chlorobenzyl)-4-thioxo-5-arylazo-imidazolidin-2-ones, five 3-(4-nitrobenzyl)-5-arylidenethiazolidine-2,4-diones and three 3-(4-phenyl-phenacyl)-4-thioxo-5-arylidenethiazolidin-2-ones have been described. These new products were synthesized by an aldolisation-crotonisation reaction from aromatic aldehydes and 3-substituted thioxothiazolidin-2-ones or thiazolidine-2,4-diones. The arylazo-imidazolidine compounds were synthesized by copulation of diazonium ions with imidazolidines. Antimicrobial activity was determined for some compounds.
Brandão
S S
SS
Departamento de Antibióticos, Universidade Federal de Pernambuco, Cidade Universitária, Recife, Brasil.
Rocha Filho
J A
JA
Chantegrel
J
J
Albuquerque
J F
JF
Ximenes
E A
EA
Galdino
S L
SL
Pitta
I R
IR
Perrissin
M
M
Luu-Duc
C
C
D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D013844:Thiazoles / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology
D000890:Anti-Infective Agents; D000935:Antifungal Agents; D013844:Thiazoles