title: Protoporphyrin derivatives--the use in localization of neoplasmas by titanium laser-induced fluorescence technique.
abstract: Examples of in vivo detection of skin neoplasmas (Mercl, melanoma) and breast carcinoma using laser induced fluorescence (LIF) and bis-1[1-alanylo-N]-ethylodeuteroporphyrin (Ala-PP) are described in this study. Photosensitizer, wave titanium laser and standard CCD camera coupled to vision amplifier enable precise neoplasm imaging, Ala-PP retention monitoring and further photodynamic therapy (PDT).
authors.affiliation: Optoelectronics Institute, Technical Military Academy, Warsaw, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Kwaśny
authors.forename: Z
authors.initials: Z
authors.lastname: Mierczyk
authors.forename: P
authors.initials: P
authors.lastname: Fiedor
authors.forename: W
authors.initials: W
authors.lastname: Rowiński
authors.forename: K
authors.initials: K
authors.lastname: Socha
authors.forename: A
authors.initials: A
authors.lastname: Graczyk
authors.forename: J
authors.initials: J
authors.lastname: Domaniecki
authors.forename: A P
authors.initials: AP
authors.lastname: Mazurek
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis*; D002277:Carcinoma / Q000175:diagnosis*; D015266:Carcinoma, Merkel Cell / Q000175:diagnosis; D005260:Female; D006414:Hematoporphyrin Photoradiation; D006801:Humans; D007834:Lasers; D008545:Melanoma / Q000175:diagnosis*; D011524:Protoporphyrins / Q000737:chemistry; D012878:Skin Neoplasms / Q000175:diagnosis*; D013050:Spectrometry, Fluorescence
chemical_list: D011524:Protoporphyrins