title: Palliation of a malignant gastrocolic fistula by endoscopic human fibrin sealant injection.
abstract: We report the case of a female patient with Hodgkin's disease resistant to therapy who developed a gastrocolic fistula as a consequence of her disease, leading to distressing faeculent vomiting. This was not considered to be amenable to surgical resection and her symptoms were successfully palliated endoscopically using injection of human fibrin sealant into the gastric and colonic aspect of the fistula tract. Both mechanical sealing and promotion of healing by human fibrin sealant are likely to be responsible for its efficacy.
authors.affiliation: Gastrointestinal Unit, Western General Hospital, Edinburgh, UK.
authors.forename: A
authors.initials: A
authors.lastname: Shand
authors.forename: S
authors.initials: S
authors.lastname: Reading
authors.forename: J
authors.initials: J
authors.lastname: Ewing
authors.forename: B
authors.initials: B
authors.lastname: Neil
authors.forename: D
authors.initials: D
authors.lastname: Welsh
authors.forename: A
authors.initials: A
authors.lastname: Parker
authors.forename: S
authors.initials: S
authors.lastname: Ghosh
mesh_terms: D000328:Adult; D004724:Endoscopy; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage / Q000627:therapeutic use*; D005747:Gastric Fistula / Q000188:drug therapy* / Q000209:etiology; D006689:Hodgkin Disease / Q000150:complications; D006801:Humans; D015552:Injections, Intralesional; D007412:Intestinal Fistula / Q000188:drug therapy* / Q000209:etiology; D010166:Palliative Care
chemical_list: D015718:Fibrin Tissue Adhesive