title: [Analgesia in breast surgery with interpleural bupivacaine].
abstract: A control group of 15 patients undergoing breast surgery was given general anesthesia. In 15 other patients an interpleural block with 0.4 ml/kg bupivacaine, 0.5%, was performed 20 minutes before induction of general anesthesia for pre-emptive analgesia. This was extended further by continuous administration of bupivacaine 0.25%, 0.125 ml/kg/hr by automatic infusion pump, with supplements of opiates for postoperative pain management. The combined technique was associated with significantly reduced perioperative opiate requirement with better emergence from anesthesia, fewer side effects, a prolonged pain-free period, and overall better quality of postoperative recovery.
authors.affiliation: Dept. of Anesthesiology, HaEmek Medical Center, Afula.
authors.forename: Z
authors.initials: Z
authors.lastname: Crystal
authors.forename: Y
authors.initials: Y
authors.lastname: Katz
mesh_terms: D000698:Analgesia / Q000379:methods*; D000768:Anesthesia, General; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007263:Infusions, Parenteral; D008197:Lymph Node Excision; D008408:Mastectomy; D015409:Mastectomy, Radical; D015412:Mastectomy, Segmental; D015413:Mastectomy, Simple; D008875:Middle Aged; D010149:Postoperative Pain; D010994:Pleura; D011292:Premedication
chemical_list: D000779:Anesthetics, Local; D002045:Bupivacaine