title: Rational approach to combined carotid and ischaemic heart disease.
abstract: BACKGROUND
  The management of patients with concomitant coronary and carotid artery disease remains a controversial subject. The aim of this review was to develop a rational plan for the management of such patients based on a review of the literature.
  
  
  RESULTS
  A retrospective review was carried out of relevant papers derived from the Medline database from 1964 to 1996.
  
  
  CONCLUSIONS
  The management of patients with concomitant coronary and carotid artery disease has not yet been put to the test in a properly designed and randomized multicentre trial. It is suggested that, until the results of such a trial are available, the rational approach to combined symptomatic disease is combined carotid endarterectomy and coronary artery bypass grafting (CABG). Combined surgery is also appropriate for patients with symptomatic carotid artery disease and significant but asymptomatic cardiac disease. At present there is inadequate evidence to promote carotid endarterectomy for asymptomatic disease in combination with CABG.
authors.affiliation: Department of Vascular, Hammersmith Hospital, London, UK.
authors.forename: S
authors.initials: S
authors.lastname: Renton
authors.forename: P
authors.initials: P
authors.lastname: Hornick
authors.forename: K M
authors.initials: KM
authors.lastname: Taylor
authors.forename: P A
authors.initials: PA
authors.lastname: Grace
mesh_terms: D002340:Carotid Artery Diseases / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D003327:Coronary Disease / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D016894:Endarterectomy, Carotid; D006801:Humans; D017202:Myocardial Ischemia / Q000150:complications* / Q000175:diagnosis / Q000601:surgery; D012189:Retrospective Studies