title: Risk factors, clinical features and outcome of Acinetobacter bacteremia in adults.
abstract: The medical records of 39 patients with Acinetobacter bacteremia identified in the period between 1985 and 1995 were reviewed. In 24 cases (62%) the bacteremia was considered to have been clinically significant. Most of the infections (79%) were nosocomial, and the majority of these were acquired in an intensive care unit. Ten (42%) patients developed septic shock complicating the bacteremia and 13 (54%) died. In most of these cases (85%), Acinetobacter bacteremia was thought to have caused or contributed to death. The following variables were associated with a greater risk of mortality: age > 65 years (OR = 16; p = 0.01); development of septic shock (OR = 22; p = 0.004); and the presence of coagulopathy (OR = 20; p = 0.03).
authors.affiliation: Department of Microbiology, Sunnybrook Health Science Centre, North York, Ontario, Canada.
authors.forename: S M
authors.initials: SM
authors.lastname: Poutanen
authors.forename: M
authors.initials: M
authors.lastname: Louie
authors.forename: A E
authors.initials: AE
authors.lastname: Simor
mesh_terms: D000150:Acinetobacter / Q000187:drug effects; D000151:Acinetobacter Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000401:mortality; D000328:Adult; D000367:Age Factors; D000368:Aged; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D016470:Bacteremia / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D001778:Blood Coagulation Disorders / Q000150:complications; D003428:Cross Infection / Q000382:microbiology; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D012772:Shock, Septic / Q000175:diagnosis / Q000453:epidemiology / Q000401:mortality
chemical_list: D000900:Anti-Bacterial Agents