Cerebral venous thrombosis in nephrotic syndrome.
This report describes cerebral venous sinus thrombosis, a rare and perhaps under-diagnosed complication of nephrotic syndrome. We review the pathophysiology of the coagulopathy associated with nephrotic syndrome including abrupt renal loss of antithrombin III. We propose a rationale approach to treating this condition with low-molecular-weight heparin and antithrombin III replacement.
Akatsu
H
H
Stanford University Medical Center, CA, USA.
Vaysburd
M
M
Fervenza
F
F
Peterson
J
J
Jacobs
M
M
D000368:Aged; D000990:Antithrombin III / Q000032:analysis / Q000627:therapeutic use; D016572:Cyclosporine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009404:Nephrotic Syndrome / Q000150:complications* / Q000188:drug therapy; D012851:Sinus Thrombosis, Intracranial / Q000150:complications*
D016572:Cyclosporine; D000990:Antithrombin III