Application of hemodilution in microsurgical free flap transplantation.
The intra-operative hemodilution and blood auto-transfusion is a blood-saving technique that can be performed when major blood loss is expected. The effects of this technique were studied in 30 microsurgical free flap transplantation patients. Between 400-600 ml blood was collected from the patients before surgery. The patients received dextran, a balanced salt solution, and glucose with the ratio of 3:1 to the collected blood volume, bleeding, and urine before the blood auto-transfusion. There were no significant changes in RBC, HCT, MCV, blood pressure, or heart rate. Of the 30 free flaps, 28 were successful with a 93.3% survival rate. The safety of intra-operative hemodilution and autologous blood transfusion in microsurgery as well as the effect of hemodilution on transplanted flap survival are discussed in this study.
Qiao
Q
Q
Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Beijing.
Zhou
G
G
Chen
G Y
GY
Ling
Y C
YC
Zhang
F
F
Buncke
H J
HJ
D000328:Adult; D001804:Blood Transfusion, Autologous; D003911:Dextrans; D005260:Female; D006438:Hemodilution; D006488:Hemostasis, Surgical; D006801:Humans; D008297:Male; D008866:Microsurgery; D010952:Plasma Substitutes; D013524:Surgical Flaps
D003911:Dextrans; D010952:Plasma Substitutes