The effects of essential fatty acids preparation in the treatment of intrauterine growth retardation.
A treatment of intravenous infusion of glucose, amino acids, and emulsion enriched in essential fatty acids (EFAs), linoleic, and linolenic acids were given to 30 pregnant women with intrauterine growth retardation (IUGR) and 28 non-EFAs treated cases as controls. There was a marked gain in fetal biparietal diameter (BPD) and in the estimated weight of the treated group over the control group. The mean birth weight was significantly different in the two groups. Fetal BPD increased much more in patients treated with EFAs at 28-34 gestational weeks than those at 34 1/7-37 weeks, which indicates that early initiate complement of n-3 and n-6 fatty acids to IUGR mothers may correct pregnancy-induced EFAs deficiency and maternal-fetal malnutrition, which demonstrates a fetal catch-up of growth in the brain and the whole body.
Zhang
L
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Department of Obstetrics and Gynecology, Xiangya Hospital, Human Medical University, Changsha, China.
D000328:Adult; D019160:Endosonography; D005228:Fatty Acids, Essential / Q000008:administration & dosage / Q000494:pharmacology*; D005260:Female; D005317:Fetal Growth Retardation / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005333:Fetus / Q000187:drug effects* / Q000502:physiology; D005865:Gestational Age; D006801:Humans; D007262:Infusions, Intravenous; D011247:Pregnancy; D011446:Prospective Studies
D005228:Fatty Acids, Essential