title: Some properties of a measure of resolution in gel electrophoresis and capillary zone electrophoresis.
abstract: The most commonly used measure of resolution for chromatographic and electrophoretic separations does not take into account the possibility of there being different amounts of each of the molecular species. A modification of a measure of resolution recently suggested by Aldroubi and Garner (BioTechniques 1992, 13, 620-624) can incorporate this effect explicitly. Their criterion for resolution is based on the time to observe a valley of specified magnitude separating two peaks. We examine how this measure depends on different physically relevant parameters that characterize the system.
authors.affiliation: Division of Computer Research and Technology, National Institutes of Health, Bethesda, MD 20892, USA. ghw@helix.nih.gov
authors.forename: G H
authors.initials: GH
authors.lastname: Weiss
authors.forename: J E
authors.initials: JE
authors.lastname: Kiefer
mesh_terms: D004247:DNA / Q000302:isolation & purification; D004586:Electrophoresis / Q000706:statistics & numerical data; D019075:Electrophoresis, Capillary / Q000706:statistics & numerical data; D011506:Proteins / Q000302:isolation & purification; D012680:Sensitivity and Specificity
chemical_list: D011506:Proteins; D004247:DNA