Secondary collapsing glomerulopathy associated with Loa loa filariasis.
This is the first case of nonprimary collapsing focal segmental glomerulosclerosis (FSGS) associated with Loa loa filariasis. Loa loa micofilariae were detected on a blood smear after a patient presented with nephrotic syndrome (NS), microhematuria, and renal failure. The renal biopsy showed a collapsing glomerulopathy variant of FSGS. Microfilariae also were identified in renal microvasculature, including the afferent arterioles and the glomerular and peritubular capillaries.
Pakasa
N M
NM
Department of Pathology, University Hospital of Kinshasha, Democratic Republic of Congo, Zaire. kim.solez@ualberta.ca
Nseka
N M
NM
Nyimi
L M
LM
D058186:Acute Kidney Injury / Q000469:parasitology; D000818:Animals; D001160:Arterioles / Q000469:parasitology; D002196:Capillaries / Q000469:parasitology; D005260:Female; D005923:Glomerulosclerosis, Focal Segmental / Q000469:parasitology* / Q000473:pathology; D006417:Hematuria / Q000469:parasitology; D006801:Humans; D007668:Kidney / Q000098:blood supply; D007678:Kidney Glomerulus / Q000098:blood supply / Q000469:parasitology / Q000473:pathology; D007684:Kidney Tubules / Q000098:blood supply; D008117:Loa; D008118:Loiasis / Q000097:blood / Q000150:complications*; D008833:Microcirculation / Q000469:parasitology; D008875:Middle Aged; D009404:Nephrotic Syndrome / Q000469:parasitology