Prevention of catheter-associated urinary tract infection by meatal disinfection.
The incidence of catheter-associated urinary tract infections (UTIs) becomes higher with prolongation of the indwelling period of a catheter. As to the entry of bacteria, ascending UTIs have now attracted attention. In the present study. the metal area was examined bacteriologically and the possibility to use antiseptics for blocking the route of developing infections was investigated. The subjects included 72 patients with an indwelling, urethral catheter inserted post-operatively. These patients were divided into three groups treated with once or twice daily application of povidone-iodine or once daily application of povidone-iodine cream. In these groups, the relation between changes in isolation of bacteria from the meatal area and the incidence of UTI was evaluated. It was found that reduction in bacterial count by antisepsis is effective to prevent ascending UTIs. Moreover, once daily application of povidone-iodine was proven to be effective in male patients. The effective antisepsis in females was twice daily application of povidone-iodine.
Matsumoto
T
T
Department of Urology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Sakumoto
M
M
Takahashi
K
K
Kumazawa
J
J
D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000627:therapeutic use*; D000985:Antisepsis; D001419:Bacteria / Q000187:drug effects / Q000254:growth & development; D001437:Bacteriuria / Q000382:microbiology / Q000652:urine; D019117:Burkholderia / Q000187:drug effects; D002408:Catheters, Indwelling / Q000009:adverse effects*; D018890:Chemoprevention; D015169:Colony Count, Microbial; D004755:Enterobacteriaceae / Q000187:drug effects / Q000254:growth & development; D004756:Enterobacteriaceae Infections / Q000517:prevention & control; D016983:Enterococcus / Q000187:drug effects / Q000254:growth & development; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000517:prevention & control; D006801:Humans; D015994:Incidence; D007466:Iodophors / Q000627:therapeutic use*; D008297:Male; D011182:Postoperative Care; D011206:Povidone-Iodine / Q000008:administration & dosage / Q000627:therapeutic use*; D012737:Sex Factors; D013203:Staphylococcal Infections / Q000517:prevention & control; D013210:Staphylococcus / Q000187:drug effects / Q000254:growth & development; D014521:Urethra / Q000187:drug effects* / Q000382:microbiology; D014546:Urinary Catheterization / Q000009:adverse effects / Q000295:instrumentation*; D014552:Urinary Tract Infections / Q000517:prevention & control*
D000891:Anti-Infective Agents, Local; D007466:Iodophors; D011206:Povidone-Iodine