title: [Oral, facial and cranial manifestations of von Recklinghausen neurofibromatosis (NF)].
abstract: 19 patients with neurofibromatosis (NF) type 1 were evaluated retrospectively. Many patients presented not only with orocraniofacial neurofibromas but also with cranial skeletal deformities--involving skullbase, skull, orbit, midface and mandibula--and ophthalmological and dental symptoms, as well as neurological disorders. Malignant transformation of NF was observed in 1 case. Severe manifestations of NF were associated with the plexiform growth type. Due to the nature of NF surgical treatment most often is only palliative.
authors.affiliation: Klinik und Poliklinik für Mund-, Kiefer- und Gesichtschirurgie, Eberhard-Karls-Universität, Tübingen.
authors.forename: C
authors.initials: C
authors.lastname: Keutel
authors.forename: B
authors.initials: B
authors.lastname: Vees
authors.forename: M
authors.initials: M
authors.lastname: Krimmel
authors.forename: C P
authors.initials: CP
authors.lastname: Cornelius
authors.forename: N
authors.initials: N
authors.lastname: Schwenzer
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005145:Face / Q000473:pathology; D005153:Facial Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000473:pathology; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D009456:Neurofibromatosis 1 / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D012886:Skull / Q000473:pathology; D012888:Skull Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology