title: [Responders and nonresponders of ultraviolet A-1 therapy of acute exacerbated atopic eczema].
abstract: Of 46 patients with severe atopic eczema treated with UVA-1, 14 were evaluated as non-responders and 32 as responders. Responding patients significantly had (p < 0.05) more severe skin involvement before onset of treatment (clinical severity score SCORAD 62.7 +/- 12.4 points) compared to non-responders (53.0 +/- 10.6 points). Serum levels of total IgE, ECP and sIL2R before treatment did not show any significant differences between the two groups. The data confirm the efficacy of UVA-1 treatment in severe cases of atopic eczema.
authors.affiliation: Hautklinik Vogtlandklinikum Plauen.
authors.forename: L
authors.initials: L
authors.lastname: Kowalzick
authors.forename: J M
authors.initials: JM
authors.lastname: Pönnighaus
authors.forename: M
authors.initials: M
authors.lastname: Suckow
authors.forename: T
authors.initials: T
authors.lastname: Waldmann
mesh_terms: D000328:Adult; D001798:Blood Proteins / Q000378:metabolism; D003876:Dermatitis, Atopic / Q000145:classification / Q000276:immunology / Q000532:radiotherapy*; D047091:Eosinophil Granule Proteins; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D008297:Male; D008875:Middle Aged; D015375:Receptors, Interleukin-2 / Q000097:blood; D012260:Ribonucleases; D016896:Treatment Outcome; D014467:Ultraviolet Therapy
chemical_list: D001798:Blood Proteins; D047091:Eosinophil Granule Proteins; D015375:Receptors, Interleukin-2; D007073:Immunoglobulin E; D012260:Ribonucleases