Occupational asthma due to porcine pancreatic amylase.
A case of occupational asthma in a 41 year old histopathology laboratory technician attributable to a powder preparation of the porcine pancreatic enzyme amylase is reported. The diagnosis was confirmed by a double blind, placebo controlled, inhalation challenge study which showed immediate and late asthmatic reactions associated with a significant increase in airway responsiveness to methacholine.
Aiken
T C
TC
Department of Respiratory Medicine, Royal Victoria Infirmary, University of Newcastle upon Tyne.
Ward
R
R
Peel
E T
ET
Hendrick
D J
DJ
D000328:Adult; D000681:Amylases / Q000009:adverse effects*; D000818:Animals; D001249:Asthma / Q000139:chemically induced*; D001985:Bronchial Provocation Tests; D004311:Double-Blind Method; D005541:Forced Expiratory Volume; D006801:Humans; D008297:Male; D017056:Medical Laboratory Personnel; D009784:Occupational Diseases / Q000139:chemically induced*; D010919:Placebos; D013552:Swine
D010919:Placebos; D000681:Amylases