title: Effects of hyperthermal stress on the ultrastructure of platelets with reference to the localization of platelet peroxidase and fibrinogen in vivo.
abstract: Ultrastructure of platelets with the localization of platelet peroxidase and fibrinogen through 3-min 47 degrees C hot-spring bathing was investigated in eight healthy volunteers. The mean sublingual temperature rose about 1.8 degrees C 5 min after the start of bathing. The frequencies of fold, pseudopods, vacuoles, and centralization were increased after bathing. Platelet peroxidase activity was decreased after bathing. Furthermore, fibrinogen was decreased in alpha-granules after bathing. Thus, hyperthermal stress in vivo may activate platelets, resulting in consumption of platelet peroxidase and fibrinogen.
authors.affiliation: Department of Medicine, Kusatsu Branch Hospital, Gunma University Hospital, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Kurabayashi
authors.forename: K
authors.initials: K
authors.lastname: Kubota
authors.forename: H
authors.initials: H
authors.lastname: Take
authors.forename: K
authors.initials: K
authors.lastname: Tamura
authors.forename: T
authors.initials: T
authors.lastname: Shirakura
mesh_terms: D000328:Adult; D001494:Baths / Q000009:adverse effects; D001792:Blood Platelets / Q000378:metabolism / Q000648:ultrastructure*; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D005340:Fibrinogen / Q000378:metabolism* / Q000648:ultrastructure; D006358:Hot Temperature / Q000009:adverse effects*; D006801:Humans; D008297:Male; D009195:Peroxidase / Q000378:metabolism* / Q000648:ultrastructure; D015539:Platelet Activation; D013312:Stress, Physiological / Q000097:blood* / Q000209:etiology
chemical_list: D005340:Fibrinogen; D009195:Peroxidase