title: Clinics in diagnostic imaging (29). Thalassaemia major with iron overload.
abstract: A 5-year-old girl presented with lethargy, anaemia and facial distortion. Both parents had beta-thalassaemia minor. Radiographs confirmed the characteristic features of thalassaemia major. A treatment regime comprising regular blood transfusions was commenced. The basis of the radiographic changes and the current role of magnetic resonance imaging, particularly with respect to assessing iron overload, are emphasized.
authors.affiliation: Department of Diagnostic, Radiology and Organ Imaging, Chinese University of Hong Kong Shatin, Hong Kong.
authors.forename: J F
authors.initials: JF
authors.lastname: Griffith
authors.forename: A D
authors.initials: AD
authors.lastname: King
authors.forename: Y L
authors.initials: YL
authors.lastname: Chan
mesh_terms: D001803:Blood Transfusion; D002675:Child, Preschool; D005260:Female; D006801:Humans; D019190:Iron Overload / Q000175:diagnosis* / Q000209:etiology; D008279:Magnetic Resonance Imaging; D017086:beta-Thalassemia / Q000150:complications / Q000175:diagnosis* / Q000628:therapy