title: High-resolution computed tomography sampling for detection of asbestos-related lung disease.
abstract: OBJECTIVE
  We determined whether a limited number of high-resolution computed tomography (HRCT) scans will effectively screen for interstitial lung disease (ILD) in a population of individuals exposed to asbestos.
  
  
  METHODS
  We retrospectively reviewed the computed tomography studies of 49 patients exposed to asbestos. HRCT in the supine and prone positions had been performed at specifically preselected levels. Two teams of thoracic radiologists evaluated, on separate occasions: (1) all images, (2) prone images only, and (3) a single prone image through the lung bases for the presence of diffuse ILD.
  
  
  RESULTS
  A relatively high level of accuracy was obtained with a single prone scan. However, improvement to 95% or better was found when additional prone images were used.
  
  
  CONCLUSIONS
  A screening study for ILD, in this case patients exposed to asbestos, may be performed by preselected prone HRCT images only. The ease and decreased time of performing the procedure make screening relatively large patient groups for ILD more feasible.
authors.affiliation: Department of Radiology, University of Utah Health Sciences Center, Salt Lake City 84132, USA.
authors.forename: K A
authors.initials: KA
authors.lastname: Murray
authors.forename: G
authors.initials: G
authors.lastname: Gamsu
authors.forename: W R
authors.initials: WR
authors.lastname: Webb
authors.forename: C J
authors.initials: CJ
authors.lastname: Salmon
authors.forename: M J
authors.initials: MJ
authors.lastname: Egger
mesh_terms: D001194:Asbestos / Q000009:adverse effects; D001195:Asbestosis / Q000000981:diagnostic imaging*; D006801:Humans; D015588:Observer Variation; D016273:Occupational Exposure / Q000009:adverse effects; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging; D012372:ROC Curve; D012189:Retrospective Studies; D018709:Statistics, Nonparametric; D014057:Tomography, X-Ray Computed
chemical_list: D001194:Asbestos