title: Mapping of eight testis-specific genes to mouse chromosomes.
abstract: We previously identified eight testis-specific genes using antibodies raised against testicular germ cells. They are expressed during spermatogenesis and are presumed to be involved in testicular germ cell differentiation and sperm formation. We have mapped the genomic loci for these testis-specific genes using restriction fragment length variants in interspecific backcross mice. The calmegin gene (Clgn) was mapped to Chr 8. The synaptonemal complex protein gene 1 (Sycp1) probe hybridized with two sequences on different chromosomes; Sycp1-rs2 was mapped to Chr 3, whereas Sycp1-rs3 was mapped to Chr 7. The relaxin-like factor gene (Rlnl) was mapped to Chr 8, and collapsin response mediator protein 1 (Crmp1) was mapped to Chr 5. Three novel genes encoding testis-specific proteins A2 (Tsga2), A8 (Tsga8), and A12 (Tsga12) were mapped to chromosomes 3, X, and 10, respectively.
authors.affiliation: Laboratory of Biomedical Genetics, Graduate School of Pharmaceutical Sciences, University of Tokyo, Japan. taketo@mol.f.u-tokyo.ac.jp
authors.forename: M M
authors.initials: MM
authors.lastname: Taketo
authors.forename: Y
authors.initials: Y
authors.lastname: Araki
authors.forename: A
authors.initials: A
authors.lastname: Matsunaga
authors.forename: A
authors.initials: A
authors.lastname: Yokoi
authors.forename: J
authors.initials: J
authors.lastname: Tsuchida
authors.forename: Y
authors.initials: Y
authors.lastname: Nishina
authors.forename: M
authors.initials: M
authors.lastname: Nozaki
authors.forename: H
authors.initials: H
authors.lastname: Tanaka
authors.forename: M
authors.initials: M
authors.lastname: Koga
authors.forename: K
authors.initials: K
authors.lastname: Uchida
authors.forename: K
authors.initials: K
authors.lastname: Matsumiya
authors.forename: A
authors.initials: A
authors.lastname: Okuyama
authors.forename: J M
authors.initials: JM
authors.lastname: Rochelle
authors.forename: Y
authors.initials: Y
authors.lastname: Nishimune
authors.forename: M
authors.initials: M
authors.lastname: Matsui
authors.forename: M F
authors.initials: MF
authors.lastname: Seldin
mesh_terms: D000818:Animals; D002135:Calcium-Binding Proteins / Q000235:genetics; D037281:Calnexin; D002874:Chromosome Mapping; D003433:Crosses, Genetic; D004268:DNA-Binding Proteins; D005796:Genes / Q000235:genetics*; D007328:Insulin; D008297:Male; D051379:Mice; D008809:Mice, Inbred C3H; D018832:Molecular Chaperones; D008969:Molecular Sequence Data; D009115:Muridae; D009419:Nerve Tissue Proteins / Q000235:genetics; D009687:Nuclear Proteins / Q000235:genetics; D010750:Phosphoproteins / Q000235:genetics; D012150:Polymorphism, Restriction Fragment Length; D011506:Proteins / Q000235:genetics; D013091:Spermatogenesis / Q000235:genetics*; D013737:Testis / Q000502:physiology*; D000098855:Collapsin Response Mediator Protein 1
chemical_list: D002135:Calcium-Binding Proteins; D004268:DNA-Binding Proteins; D007328:Insulin; C084797:Leydig insulin-like protein; D018832:Molecular Chaperones; D009419:Nerve Tissue Proteins; D009687:Nuclear Proteins; D010750:Phosphoproteins; D011506:Proteins; C489754:Sycp1 protein, mouse; D000098855:Collapsin Response Mediator Protein 1; D037281:Calnexin; C087341:calmegin