title: Diagnostic and microsurgical presentation of intracranial angiolipomas. Case report and review of the literature.
abstract: Angiolipomas (ALs) are hamartomas composed of abnormally differentiated vessels and mature adipose tissue. Although they are most commonly found in peripheral tissues, ALs sometimes grow in the spinal epidural space. Intracranial ALs (ICALs) are rare: only seven cases have been reported in the literature. The authors describe the case of a 70-year-old woman who presented with ocular symptoms from a clinically and radiologically progressing parasellar ICAL. The radiological as well as the microsurgical findings are illustrated and compared with the seven previously published cases. The most frequent location of ALs is the skull base, especially the parasellar region. Other ICALs were diagnosed as components of cerebral arteriovenous malformations and were not symptomatic by themselves. Neuroradiological studies of ICALs usually demonstrate the characteristics of both adipose and vascular tissues. However, a review of the literature shows that the diagnosis had not been suspected preoperatively in any of the cases. Operative descriptions emphasize that most neurosurgeons were caught off guard by the profuse bleeding and the unusual relationship of this unexpected lesion to the cavernous sinus, so that removal was rarely complete. The authors conclude that preoperative diagnosis of ICALs is achievable based on magnetic resonance analysis, which should help optimize the microsurgical management of these lesions.
authors.affiliation: Department of Neurosurgery, Université Libre de Bruxelles, Erasme Hospital, Brussels, Belgium.
authors.forename: B
authors.initials: B
authors.lastname: Pirotte
authors.forename: B
authors.initials: B
authors.lastname: Krischek
authors.forename: M
authors.initials: M
authors.lastname: Levivier
authors.forename: S
authors.initials: S
authors.lastname: Bolyn
authors.forename: J M
authors.initials: JM
authors.lastname: Brucher
authors.forename: J
authors.initials: J
authors.lastname: Brotchi
mesh_terms: D000368:Aged; D018206:Angiolipoma / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D001932:Brain Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008866:Microsurgery; D014057:Tomography, X-Ray Computed