title: Effects of milk-borne colony stimulating factor-1 on circulating growth factor levels in the newborn infant.
abstract: Colony stimulating factor-1 (CSF-1) concentrations in colostrum were 20 to 25 times higher than in serum at birth and declined with lactation. No difference in concentrations of circulating CSF-1, however, were noted between breast-fed and formula-fed infants, suggesting that milk-borne CSF-1 may feed back negatively on endogenous growth factor levels, may act locally in the gastrointestinal tract, or may be locally degraded.
authors.affiliation: Department of Pediatrics, Albert Einstein College of Medicine-Montefiore Medical Center, Bronx, New York, USA.
authors.forename: O
authors.initials: O
authors.lastname: Flidel-Rimon
authors.forename: P
authors.initials: P
authors.lastname: Roth
mesh_terms: D000818:Animals; D005260:Female; D005526:Food, Formulated; D005865:Gestational Age; D006133:Growth Substances / Q000097:blood*; D006801:Humans; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D016173:Macrophage Colony-Stimulating Factor / Q000097:blood*; D008297:Male; D008895:Milk, Human / Q000737:chemistry*; D011863:Radioimmunoassay
chemical_list: D006133:Growth Substances; D016173:Macrophage Colony-Stimulating Factor