title: In utero eyeball development study by magnetic resonance imaging.
abstract: The aim of this study was to measure fetal ocular development and to determine a growth curve by means of measurements in utero. Fetal ocular development was recorded by analysis of the results of magnetic resonance imaging (MRI). An anatomic study allowed definition of the best contrasted MRI sequences for calculation of the ocular surface. Biometric analysis of the values of the ocular surface in the neuro-ocular plane in 35 fetuses allowed establishment of a linear model of ocular growth curve in utero. Evaluation of ocular development may allow the detection and confirmation of malformational ocular anomalies such as microphthalmia.
authors.affiliation: Institut d'Anatomie des Saints Pères, Paris, France.
authors.forename: D S
authors.initials: DS
authors.lastname: Brémond-Gignac
authors.forename: K
authors.initials: K
authors.lastname: Benali
authors.forename: S
authors.initials: S
authors.lastname: Deplus
authors.forename: O
authors.initials: O
authors.lastname: Cussenot
authors.forename: L
authors.initials: L
authors.lastname: Ferkdadji
authors.forename: M
authors.initials: M
authors.lastname: Elmaleh
authors.forename: J P
authors.initials: JP
authors.lastname: Lassau
mesh_terms: D005314:Embryonic and Fetal Development; D005123:Eye / Q000196:embryology*; D005865:Gestational Age; D006801:Humans; D008279:Magnetic Resonance Imaging; D008850:Microphthalmos / Q000175:diagnosis; D013997:Time Factors