title: Effect of endurance training on pancreatic enzyme activity in rats.
abstract: The effect of chronic exercise on pancreatic enzyme activity and basal pancreatic secretion was investigated in rats. Male Wistar rats were divided into three groups of ten rats each. In a trained (T) group, the animals were exercised on a treadmill at 35 m x min(-1) for 60 min, 5 days x week(-1). A free-fed control (C) group and a pair-fed control (PFC) group were kept sedentary. Food intake in the PFC group was restricted to the T group levels. After 6 weeks, pancreas wet mass per unit of body mass was significantly larger in the T group in comparison to the C and PFC groups. Protein content, and amylase and lipase activities of the pancreas were significantly higher in the T group in comparison to the C and PFC groups. Basal amylase but not bile-pancreatic juice volume was higher in the T group than in the other two groups. There were no significant differences between groups C and PFC in any of the above parameters. These results would suggest that pancreatic enzyme synthesis and basal secretion are accelerated with physical endurance training. This adjustment would be a beneficial adaptation to chronic endurance exercise, which requires a large energy supply from food.
authors.affiliation: Wayo Women's University, Chiba, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Minato
mesh_terms: D000681:Amylases / Q000378:metabolism; D000818:Animals; D001646:Bile / Q000378:metabolism; D008049:Lipase / Q000378:metabolism; D008297:Male; D010179:Pancreas / Q000201:enzymology*; D010189:Pancreatic Juice / Q000378:metabolism; D010807:Physical Endurance; D005082:Physical Exertion; D051381:Rats; D017208:Rats, Wistar
chemical_list: D008049:Lipase; D000681:Amylases