title: Time-frequency distribution of heart rate variability below 0.05 Hz by Wigner-Ville spectral analysis in congestive heart failure patients.
abstract: The Wigner-Ville spectral analysis was utilized to demonstrate a high-resolution time-frequency distribution of heart rate variability below 0.05 Hz. There are different time-frequency characteristics between the normal subject and the patient with severe congestive heart failure. The former consists of multiple and broad-band spectral peaks, while the latter presents unique spectral peaks. Based on Bayes theory, a classifier for the unique spectral peaks was developed. After the beneficial improvement with low-dose beta-blockers, the unique spectral peaks had disappeared or the time of occurrence was reduced in most patients.
authors.affiliation: Department of Electrical Engineering, National Taiwan University, Taipei, Republic of China.
authors.forename: H L
authors.initials: HL
authors.lastname: Chan
authors.forename: J L
authors.initials: JL
authors.lastname: Lin
authors.forename: C C
authors.initials: CC
authors.lastname: Du
authors.forename: C P
authors.initials: CP
authors.lastname: Wu
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D001499:Bayes Theorem; D002639:Cheyne-Stokes Respiration / Q000145:classification / Q000175:diagnosis / Q000503:physiopathology; D002908:Chronic Disease; D015716:Electrocardiography, Ambulatory / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data; D005583:Fourier Analysis; D006333:Heart Failure / Q000175:diagnosis* / Q000188:drug therapy / Q000503:physiopathology; D006339:Heart Rate; D006801:Humans; D008875:Middle Aged; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation; D013997:Time Factors
chemical_list: D000319:Adrenergic beta-Antagonists