[Human intestinal microsporidiosis in Bamako (Mali): the presence of Enterocytozoon bieneusi in HIV seropositive patients].
A study was conducted between 1993 and 1996 in Bamako to determine the rate of occurrence of microsporidia in 88 patients. Most (80%) had chronic diarrhea associated with weight loss and 87.5% were HIV-positive. Intestinal microsporidia were detected in 32% of the patients infected with HIV-1, HIV-2, or coinfected with both strains. Microsporidiosis was also diagnosed in three of the eleven HIV-negative individuals (27%). Microsporidiosis was confirmed by electron microscopy in 6 HIV-positive patients and 1 HIV-negative individual. Enterocytozoon bieneusi was detected in each case. These results suggest that microsporidia are common pathogens in HIV-positive patients in Bamako. Cases of microsporidiosis have been reported for the first time in HIV-2-infected patients. The proportion of women microsporidiosis patients is higher in Mali than in industrialized countries. The presence of microsporidia in HIV-negative patients suggests that these parasites may be an underestimated cause of enteritis in developing countries.
Maiga
I
I
Laboratoire de biologie médicale, Hôpital national du Point G, Bamako, Mali.
Doumbo
O
O
Dembele
M
M
Traoré
H
H
Desportes-Livage
I
I
Hilmarsdottir
I
I
Giboyau
E
E
Maiga
L
L
Kassambara
L
L
el Fakhry
Y
Y
Datry
A
A
Gentilini
M
M
Pichard
E
E
D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology / Q000469:parasitology*; D000328:Adult; D000368:Aged; D000818:Animals; D002908:Chronic Disease; D019049:Developed Countries / Q000706:statistics & numerical data; D003906:Developing Countries / Q000706:statistics & numerical data; D003967:Diarrhea / Q000453:epidemiology / Q000469:parasitology; D004751:Enteritis / Q000453:epidemiology / Q000469:parasitology; D005260:Female; D018023:HIV Seronegativity; D006679:HIV Seropositivity / Q000453:epidemiology / Q000469:parasitology*; D015497:HIV-1; D015498:HIV-2; D006801:Humans; D007411:Intestinal Diseases, Parasitic / Q000453:epidemiology*; D008297:Male; D008302:Mali / Q000453:epidemiology; D016816:Microsporida / Q000145:classification / Q000302:isolation & purification; D016881:Microsporidiosis / Q000453:epidemiology*; D008875:Middle Aged; D012737:Sex Factors; D015431:Weight Loss