title: Sublingual nifedipine in human pregnancy.
abstract: BACKGROUND
  Nifedipine is widely used for acute lowering of blood pressure in obstetric hypertensive emergencies. It has not been approved for this indication or widely assessed.
  
  
  OBJECTIVE
  To examine retrospectively the efficacy of nifedipine over a 12 month period in a high risk obstetric service.
  
  
  METHODS
  Chart review of all patients admitted to hospital in the antenatal period with moderate to severe hypertension. Description of their management, usage of nifedipine, and pregnancy outcome.
  
  
  RESULTS
  Sublingual nifedipine resulted in significant lowering of blood pressure without hypotension. Pregnancy outcome was satisfactory in all patients.
  
  
  CONCLUSIONS
  Sublingual nifedipine was effective, easy to administer, and without serious complications in this retrospective study.
authors.affiliation: Department of Medicine, Sydney University, Royal North Shore Hospital, Sydney, NSW.
authors.forename: E D
authors.initials: ED
authors.lastname: Gallery
authors.forename: A Z
authors.initials: AZ
authors.lastname: Györy
mesh_terms: D000286:Administration, Sublingual; D001034:Apgar Score; D001724:Birth Weight; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007231:Infant, Newborn; D009543:Nifedipine / Q000627:therapeutic use*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000188:drug therapy*; D011256:Pregnancy Outcome; D012189:Retrospective Studies
chemical_list: D002121:Calcium Channel Blockers; D009543:Nifedipine