Paradoxic excitation with diphenhydramine in an adult.
Although paradoxic excitation may rarely occur in children and adults with conventional dosages of antihistamines, few case reports have appeared in the literature. We cared for a 46-year-old patient who became extremely agitated after receiving a dose of intravenous diphenhydramine.
Cheng
K L
KL
Department of Pharmacy, Bassett Healthcare, Cooperstown, New York 13326, USA.
Dwyer
P N
PN
Amsden
G W
GW
D000328:Adult; D001943:Breast Neoplasms / Q000150:complications / Q000628:therapy; D004155:Diphenhydramine / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006634:Histamine H1 Antagonists / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D011595:Psychomotor Agitation / Q000503:physiopathology*
D006634:Histamine H1 Antagonists; D004155:Diphenhydramine