Follicle aspiration, sperm injection, and assisted rupture (FASIAR): a simple new assisted reproductive technique.
OBJECTIVE
To describe the first successful application of a new fertility-enhancing technique.


METHODS
Case report.


METHODS
Academic fertility program.


METHODS
A 36-year-old nulligravid woman undergoing inseminations with frozen-thawed donor sperm.


METHODS
Ovarian superovulation, follicle aspiration, sperm injection, and assisted follicular rupture.


METHODS
Assessment of feasibility of technique and pregnancy outcome.


RESULTS
After failing to conceive during 16 cycles of IUI, the patient successfully achieved an ongoing pregnancy during the second follicle aspiration, sperm injection, and assisted rupture (FASIAR) attempt.


CONCLUSIONS
Follicle aspiration, sperm injection, and assisted rupture combines the concepts of superovulation, IUI, and peritoneal oocyte and sperm transfer to obviate the possibility of luteinized unruptured follicle syndrome, assist oocyte release, and ensure gamete intermixing. It also can be used to reduce the number of ovulating oocytes and thus to reduce the risk of multiple gestations. Follicle aspiration, sperm injection, and assisted rupture is a new, simple, office-based procedure that does not require embryologic expertise beyond sperm preparation as for IUI, yet promises to be more successful than IUI.
Paulson
R J
RJ
Department of Obstetrics and Gynecology, University of Southern California School of Medicine, Los Angeles, USA.
Thornton
M H
MH
D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008845:Microinjections; D009865:Oocytes; D006080:Ovarian Follicle; D010060:Ovulation; D011247:Pregnancy; D012099:Reproductive Techniques; D013094:Spermatozoa; D013396:Suction