title: Nonalcoholic steatohepatitis masquerading as autoimmune hepatitis.
abstract: Nonalcoholic steatohepatitis is an increasingly recognized clinicopathologic condition. We report two cases of nonalcoholic steatohepatitis in middle-aged Japanese women whose clinical and laboratory data mimicked autoimmune hepatitis. Histologic findings of both cases were definite steatohepatitis with portal and pericellular fibrosis. Both patients' HLA-DR haplotypes were DR4 and DR2, which are frequently observed in Japanese patients with autoimmune hepatitis. Our cases suggest a diversity in the pathogenesis of nonalcoholic steatohepatitis.
authors.affiliation: Second Department of Internal Medicine, Faculty of Medicine, Tokyo Medical and Dental University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Tajiri
authors.forename: H
authors.initials: H
authors.lastname: Takenawa
authors.forename: K
authors.initials: K
authors.lastname: Yamaoka
authors.forename: M
authors.initials: M
authors.lastname: Yamane
authors.forename: F
authors.initials: F
authors.lastname: Marumo
authors.forename: C
authors.initials: C
authors.lastname: Sato
mesh_terms: D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D005234:Fatty Liver / Q000473:pathology*; D005260:Female; D006505:Hepatitis / Q000473:pathology*; D019693:Hepatitis, Autoimmune / Q000473:pathology*; D006801:Humans; D008875:Middle Aged