title: Clotting factor IX levels in C/EBP alpha knockout mice.
abstract: Previous studies have indicated that C/EBP alpha is involved in the regulation of factor IX and mutations of a C/EBP recognition element in the factor IX promoter result in haemophilia B. We now report that mice homozygous for the deletion of the c/ebp alpha gene are significantly deficient in factor IX transcription.
authors.affiliation: Chemical Pathology Unit, Sir William Dunn School of Pathology, University of Oxford.
authors.forename: N
authors.initials: N
authors.lastname: Davies
authors.forename: D E
authors.initials: DE
authors.lastname: Austen
authors.forename: M D
authors.initials: MD
authors.lastname: Wilde
authors.forename: G J
authors.initials: GJ
authors.lastname: Darlington
authors.forename: G G
authors.initials: GG
authors.lastname: Brownlee
mesh_terms: D000818:Animals; D015152:Blotting, Northern; D005164:Factor IX / Q000235:genetics* / Q000378:metabolism; D051379:Mice; D018345:Mice, Knockout; D009154:Mutation; D012333:RNA, Messenger / Q000378:metabolism; D014158:Transcription, Genetic
chemical_list: D012333:RNA, Messenger; D005164:Factor IX