title: Intracochlear, electrical, multichannel stimulation effects on the development of auditory system in neonatally deafened kittens.
abstract: OBJECTIVE
  To investigate the effect of chronic electrical stimulation in acoustically deprivated animals during maturation.
  
  
  METHODS
  Latencies of EABR measurements from acoustically deprivated and acoustically deprivated, but electrically stimulated animals were compared with ABR from normal hearing cats. In addition, morphological analyses of the cochlear nuclei and the auditory cortex and their subdivisions were done.
  
  
  CONCLUSIONS
  EABR latencies demonstrated that the most peripheral auditory pathway is more independent from the normal auditory or external electrical stimulation than the more central regions. Morphological analysis also demonstrated the reverse of the acoustically deprivation effect during maturation in the auditory cortex via intracochlear electrical stimulation.
authors.affiliation: Department of Otorhinolaryngology, Medizinische Hochschule Hannover, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Reuter
authors.forename: S M
authors.initials: SM
authors.lastname: Cords
authors.forename: P
authors.initials: P
authors.lastname: Issing
authors.forename: P
authors.initials: P
authors.lastname: Keller
authors.forename: T
authors.initials: T
authors.lastname: Lenarz
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001303:Auditory Cortex / Q000502:physiology*; D002415:Cats; D019929:Cochlear Implantation; D003638:Deafness / Q000601:surgery*; D004558:Electric Stimulation / Q000295:instrumentation; D004867:Equipment Design; D016057:Evoked Potentials, Auditory, Brain Stem; D006309:Hearing / Q000502:physiology; D017966:Pyramidal Cells / Q000502:physiology