Can microwave radiation at high temperatures reduce the toxicity of fibrous crocidolite asbestos?
Exposure of animals and humans to crocidolite asbestos fibers produces fibrosis and two types of cancers: bronchogenic carcinoma and mesothelioma. It is therefore desirable to reduce toxicity of these fibers without affecting their other characteristics. In this study, commercial crocidolite asbestos fibers were radiated with microwave radiation at different temperatures. Radiated fibers and nonradiated original fibers were then studied by Mössbauer spectroscopy to quantify the amount of ferric and ferrous ions present at structurally different sites in each crocidolite sample. They were also studied for their ability to initiate the peroxidation of linoleic acid to assess the effect of radiation on this process. Results showed that microwave radiation reduced the total Fe2+/Fe3+ ratio. This reduction produced a concomitant decrease in the ability of the radiated samples to peroxidize linoleic acid.
Gulumian
M
M
Biochemistry Research Section, National Centre for Occupational Health, Johannesburg, South Africa. mary@ncoh.pwv.gov.za
Nkosibomvu
Z L
ZL
Channa
K
K
Pollak
H
H
D000447:Aldehydes / Q000737:chemistry / Q000528:radiation effects; D017638:Asbestos, Crocidolite / Q000737:chemistry / Q000528:radiation effects*; D006358:Hot Temperature; D006861:Hydrogen Peroxide / Q000737:chemistry / Q000528:radiation effects; D007501:Iron / Q000737:chemistry / Q000528:radiation effects; D008872:Microwaves; D010084:Oxidation-Reduction; D015204:Spectroscopy, Mossbauer
D000447:Aldehydes; D017638:Asbestos, Crocidolite; D006861:Hydrogen Peroxide; D007501:Iron