title: Interaction of iron(II) with bile salts.
abstract: Iron(II) ions react with small aggregates of cholate, glycocholate, chenodeoxycholate, and deoxycholate to form soluble and colloidal compounds. Taurocholate under conditions used does not react with the Fe2+ ion. Small aggregates of dihydroxy bile salts (predominating in the premicellar region, at concentrations of the bile salt above 1 mmol dm-3) have a larger affinity for Fe2+ compared to those formed from cholate anions. In their interactions with small aggregates of cholate anions, the Fe2+ ion shows an affinity comparable to that of Cu2+ and Cd2+ and somewhat larger than that of Zn2+. Small aggregates of cholate show a higher ability to mask Fe2+ than those of taurocholate and glycocholate. Interaction of glycocholic acid anions with Fe2+ ions is sufficient to prevent iron(II) precipitation.
authors.affiliation: Istituto di Scienze Chimiche, Università di Bologna, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Fini
authors.forename: G
authors.initials: G
authors.lastname: Feroci
authors.forename: G
authors.initials: G
authors.lastname: Fazio
authors.forename: P
authors.initials: P
authors.lastname: Zuman
mesh_terms: D000838:Anions; D001647:Bile Acids and Salts / Q000378:metabolism*; D002104:Cadmium / Q000378:metabolism; D002635:Chenodeoxycholic Acid / Q000378:metabolism; D019826:Cholic Acid; D002793:Cholic Acids / Q000378:metabolism; D003102:Colloids; D003300:Copper / Q000378:metabolism; D003840:Deoxycholic Acid / Q000378:metabolism; D005296:Ferrous Compounds / Q000378:metabolism*; D006000:Glycocholic Acid / Q000378:metabolism; D006868:Hydrolysis; D012995:Solubility; D013656:Taurocholic Acid / Q000378:metabolism; D015032:Zinc / Q000378:metabolism
chemical_list: D000838:Anions; D001647:Bile Acids and Salts; D002793:Cholic Acids; D003102:Colloids; D005296:Ferrous Compounds; D003840:Deoxycholic Acid; D002104:Cadmium; D002635:Chenodeoxycholic Acid; D013656:Taurocholic Acid; D003300:Copper; D019826:Cholic Acid; D006000:Glycocholic Acid; D015032:Zinc