title: [Regression of left ventricular hypertrophy in hypertensive patients].
abstract: Left ventricular hypertrophy associated with systemic hypertension differs from left ventricular hypertrophy initiated by other pressure overload diseases. Its development depends not only of hemodynamics aspects but of biochemical factors. Many studies have demonstrated a close link between left ventricular hypertrophy and cardiovascular morbidity and mortality. For that reason the idea of reversal of left ventricular hypertrophy has been a goal of the antihypertensive treatment. From the literature review has been established that the most classes of antihypertensive medications reduce the left ventricular mass, though there is a variation in required duration of treatment. At this point the angiotensin converting enzyme inhibitors, probably because a double effect: hypotensive and blockers of the trophic stimulus of angiotensin II, seemed to be the most potent for reducing the left ventricular mass. Still we don't know if reversal of left ventricular hypertrophy, by the antihypertensive treatment, reduce independently the cardiovascular risk.
authors.affiliation: Servicio de Cardiología, Hospital Universitario de Canarias, Tenerife.
authors.forename: F
authors.initials: F
authors.lastname: Bosa Ojeda
authors.forename: M
authors.initials: M
authors.lastname: García González
authors.forename: A
authors.initials: A
authors.lastname: Domínguez Rodríguez
authors.forename: A
authors.initials: A
authors.lastname: Barragán Acea
authors.forename: J M
authors.initials: JM
authors.lastname: Miralles Ibarra
authors.forename: J
authors.initials: J
authors.lastname: Lacalzada Almeida
authors.forename: D
authors.initials: D
authors.lastname: de Armas Trujillo
mesh_terms: D000804:Angiotensin II; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use*; D000959:Antihypertensive Agents / Q000627:therapeutic use; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy / Q000628:therapy; D017379:Hypertrophy, Left Ventricular / Q000209:etiology* / Q000401:mortality / Q000517:prevention & control
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D000804:Angiotensin II