title: The Mitrofanoff principle in continent urinary reconstruction.
abstract: Continent urinary diversion has increasingly become important for treating children and adults with urinary tract pathology that cannot be managed by direct reconstructive techniques. The Mitrofanoff principle, a term that has become synonymous with the flap valve mechanism for promoting the unidirectorial flow of a fluid medium, is a recapitulation of nature's design for the competent ureterovesical junction. Construction of a catheterizable channel using this principle can be performed with a variety of tissues and serves well as a continence mechanism for either the native bladder or intestinal reservoirs. In addition to its utility in managing urinary incontinence, implantation of a catheterizable channel into the cecum can be used to manage fecal incontinence in patients with neurogenic bowel dysfunction.
authors.affiliation: Department of Urology, Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: M
authors.initials: M
authors.lastname: Kaefer
authors.forename: A B
authors.initials: AB
authors.lastname: Retik
mesh_terms: D000293:Adolescent; D000328:Adult; D001065:Appendix / Q000601:surgery; D002648:Child; D003559:Cystostomy; D005242:Fecal Incontinence / Q000628:therapy; D005500:Follow-Up Studies; D006801:Humans; D007422:Intestines / Q000601:surgery; D011182:Postoperative Care; D011183:Postoperative Complications / Q000453:epidemiology; D011300:Preoperative Care; D013270:Stomach / Q000601:surgery; D014513:Ureter / Q000601:surgery; D016476:Urinary Reservoirs, Continent / Q000009:adverse effects