title: Temporal lobe necrosis in nasopharyngeal carcinoma: pictorial essay.
abstract: Nasopharyngeal carcinoma (NPC) shows a high frequency of skull base erosion and intracranial spread. This tumour is usually treated with radiation therapy. The medial and inferior portions of both temporal lobes are included within the radiation portals. These areas are therefore potential sites of radiation-induced necrosis. It is important to recognize this complication and separate it from intracranial tumour recurrence because the treatments of these entities are different.
authors.affiliation: Department of Diagnostic Radiology, Singapore General Hospital, Singapore.
authors.forename: V F
authors.initials: VF
authors.lastname: Chong
authors.forename: Y F
authors.initials: YF
authors.lastname: Fan
authors.forename: L L
authors.initials: LL
authors.lastname: Chan
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D009336:Necrosis; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D011832:Radiation Injuries / Q000175:diagnosis*; D013702:Temporal Lobe / Q000528:radiation effects*; D014057:Tomography, X-Ray Computed