Cutaneous manifestation of Chagas' disease after heart transplantation: successful treatment with allopurinol.
We describe two patients who underwent cardiac transplantation for chronic cardiomyopathy of Chagas' disease, and in whom the disease was reactivated with the development of cutaneous lesions. In both cases, the skin lesions regressed completely after 2 months of therapy with allopurinol.
Tomimori-Yamashita
J
J
Department of Dermatology, Universidade Federal de São Paulo-EPM, Brazil.
Deps
P D
PD
Almeida
D R
DR
Enokihara
M M
MM
De Seixas
M T
MT
Freymüller
E
E
D000328:Adult; D000493:Allopurinol / Q000627:therapeutic use*; D000977:Antiparasitic Agents; D002598:Chagas Cardiomyopathy / Q000601:surgery; D014355:Chagas Disease / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D016027:Heart Transplantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012876:Skin Diseases, Parasitic / Q000473:pathology; D014344:Trypanocidal Agents / Q000627:therapeutic use*
D000977:Antiparasitic Agents; D014344:Trypanocidal Agents; D000493:Allopurinol