title: Role of the suprachiasmatic nucleus in the pathogenesis of migraine attacks.
abstract: Neuroanatomic, morphometric, immunocytochemical, neurobiochemical and clinical data support the hypothesis that the suprachiasmatic nucleus of the hypothalamus might be the initial site of migraine attacks. The prodromal phase of a migraine attack could be considered a syndrome of functional suprachiasmatic nucleus insufficiency, and other phases a reactive denervation hypersensitivity with the affection of the visual, nociceptive, antinociceptive and cranial vasomotor system.
authors.affiliation: Zagreb School of Medicine, Department of Neurology, University Hospital Rebro, Croatia.
authors.forename: N
authors.initials: N
authors.lastname: Zurak
mesh_terms: D001683:Biological Clocks / Q000502:physiology; D006801:Humans; D008550:Melatonin / Q000378:metabolism; D008881:Migraine Disorders / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D010870:Pineal Gland / Q000502:physiology; D012701:Serotonin / Q000502:physiology; D012890:Sleep / Q000502:physiology; D013493:Suprachiasmatic Nucleus / Q000473:pathology / Q000502:physiology*; D014795:Visual Pathways / Q000502:physiology
chemical_list: D012701:Serotonin; D008550:Melatonin