title: Clinical experience of trabeculotomy for the surgical treatment of aniridic glaucoma.
abstract: OBJECTIVE
  The purpose of this study is to determine the efficacy of initial trabeculotomy in the patient with aniridic glaucoma.
  
  
  METHODS
  Clinical charts were reviewed.
  
  
  METHODS
  Twenty-nine eyes of 16 patients with aniridia were studied.
  
  
  METHODS
  Glaucoma surgery was performed. As an initial procedure, trabeculotomy was performed in 12 eyes, other surgery was performed in 17 eyes (trabeculectomy, 5; goniotomy, 5; other, 7).
  
  
  METHODS
  Success was defined as an intraocular pressure (IOP) of 21 mmHg or lower, and no further surgery was performed.
  
  
  RESULTS
  Ten (83%) of 12 eyes obtained IOP control after first (6 eyes) or second (4 eyes) trabeculotomy with a mean follow-up period of 9.5 years. Five eyes maintained visual acuity of 20/40 to 20/200. No serious complications were found after trabeculotomy. Three (18%) of 17 eyes were controlled with the first glaucoma surgery other than trabeculotomy (goniotomy, trabeculectomy, trabeculectomy combined with trabeculotomy, and Molteno implant). Good IOP control was obtained in 8 (47%) of 17 eyes after several surgeries with a mean follow-up period of 10.4 years. Four of 17 eyes became phthisical.
  
  
  CONCLUSIONS
  This study suggests that trabeculotomy is the preferred initial operation for uncontrolled glaucoma with aniridia.
authors.affiliation: Glaucoma Research & Education Group, San Francisco, California 94102, USA.
authors.forename: M
authors.initials: M
authors.lastname: Adachi
authors.forename: C J
authors.initials: CJ
authors.lastname: Dickens
authors.forename: J
authors.initials: J
authors.lastname: Hetherington
authors.forename: H D
authors.initials: HD
authors.lastname: Hoskins
authors.forename: A G
authors.initials: AG
authors.lastname: Iwach
authors.forename: P C
authors.initials: PC
authors.lastname: Wong
authors.forename: N
authors.initials: N
authors.lastname: Nguyen
authors.forename: A S
authors.initials: AS
authors.lastname: Ma
mesh_terms: D000293:Adolescent; D000328:Adult; D015783:Aniridia / Q000503:physiopathology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D005901:Glaucoma / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007429:Intraocular Pressure / Q000502:physiology; D018465:Molteno Implants; D014130:Trabeculectomy; D016896:Treatment Outcome; D014792:Visual Acuity