title: Villous adenoma of the bladder.
abstract: Villous adenomas of the bladder are rare tumors and up to now they have not been seen to undergo malignant transformation. We report a case of villous adenoma of the bladder with areas of adenocarcinoma in a 72-year-old man. We describe all the morphological, histochemical and immunohistochemical features characterizing this tumor. We recommend adequate pathological sampling and a thorough follow-up of patients with villous adenoma. The prognosis and the behaviour of these adenomatous papillary lesions, morphologically similar to colonic adenomas, in the bladder is unclear. We report a case with focal area of adenocarcinoma and review the literature.
authors.affiliation: Department of Pathology, University of Siena.
authors.forename: S A
authors.initials: SA
authors.lastname: Tripodi
authors.forename: L
authors.initials: L
authors.lastname: Laurini
authors.forename: L
authors.initials: L
authors.lastname: Presenti
authors.forename: C
authors.initials: C
authors.lastname: Brunettini
authors.forename: G
authors.initials: G
authors.lastname: Boncompagni
authors.forename: M
authors.initials: M
authors.lastname: Messina
authors.forename: A
authors.initials: A
authors.lastname: D'Agata
authors.forename: M T
authors.initials: MT
authors.lastname: Del Vecchio
mesh_terms: D000230:Adenocarcinoma / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D018253:Adenoma, Villous / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D018450:Disease Progression; D006417:Hematuria / Q000209:etiology; D006801:Humans; D008297:Male; D008679:Metaplasia; D009363:Neoplasm Proteins / Q000032:analysis; D009378:Neoplasms, Multiple Primary / Q000473:pathology* / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D019459:Urothelium / Q000473:pathology
chemical_list: D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins