title: Two-point Dixon technique for water-fat signal decomposition with B0 inhomogeneity correction.
abstract: To separate water and lipid resonance signals by phase-sensitive MRI, a two-point Dixon (2PD) reconstruction is presented in which phase-unwrapping is used to obtain an inhomogeneity map based on only in-phase and out-of-phase image data. Two relaxation-weighted images, a "water image" and a "fat image," representing a two-resonance peak model of proton density, are output. The method is designed for T1- or density-weighted spin-echo imaging; a double-echo scheme is more appropriate for T2-weighted spin-echo imaging. The technique is more time-efficient for clinical fat-water imaging than 3PD schemes, while still correcting for field inhomogeneity.
authors.affiliation: Department of Radiology, University of California, San Francisco 94121, USA.
authors.forename: B D
authors.initials: BD
authors.lastname: Coombs
authors.forename: J
authors.initials: J
authors.lastname: Szumowski
authors.forename: W
authors.initials: W
authors.lastname: Coshow
mesh_terms: D001940:Breast / Q000033:anatomy & histology; D005123:Eye / Q000033:anatomy & histology; D005260:Female; D006801:Humans; D008055:Lipids / Q000032:analysis*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D010388:Pelvis / Q000033:anatomy & histology; D014867:Water / Q000032:analysis*
chemical_list: D008055:Lipids; D014867:Water