title: The influence of 0.12% chlorhexidine digluconate rinses on the incidence of infectious complications and implant success.
abstract: The effect of perioperative chlorhexidine on the frequency of infectious complications through stage II was examined. Chlorhexidine was used perioperatively in 54.6% of patients (52.5% of implants) in a Dental Implant Clinical Research Group study with a database of 2,641 implants (595 patients). With chlorhexidine, there was a significant reduction in the number of infectious complications (4.1% vs 8.7%). Two percent of implants failed in the absence of an infectious complication, whereas 12% with infectious complications failed. This sixfold difference is highly significant. Chlorhexidine may reduce microbial complications when used in the immediate perioperative period.
authors.affiliation: Dental Service, Department of Veterans Affairs Medical Center, Dayton, OH, USA.
authors.forename: P M
authors.initials: PM
authors.lastname: Lambert
authors.forename: H F
authors.initials: HF
authors.lastname: Morris
authors.forename: S
authors.initials: S
authors.lastname: Ochi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000497:Alloys; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000627:therapeutic use*; D002710:Chlorhexidine / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D019992:Databases as Topic; D003722:Dental Alloys; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D017267:Dental Prosthesis Design; D019232:Dental Restoration Failure; D017886:Durapatite; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes / Q000627:therapeutic use*; D011446:Prospective Studies; D013530:Surgical Wound Infection / Q000517:prevention & control*; D014025:Titanium; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D000497:Alloys; D000891:Anti-Infective Agents, Local; D003722:Dental Alloys; D015921:Dental Implants; D009067:Mouthwashes; C031462:titanium alloy (TiAl6V4); D017886:Durapatite; D014025:Titanium; C010882:chlorhexidine gluconate; D002710:Chlorhexidine