title: Dental parameters in the long-term survivors of childhood cancer compared with siblings.
abstract: There have been a number of reports on the dental health of long-term survivors (LTS) of childhood malignancy as compared with normal controls. However, it is usually difficult to identify a meaningful control population as most of these patients are from widely differing geographical areas and socio-economic status. The aim of this investigation was, therefore, to study the dental health of LTS compared with siblings. 46 LTS who had siblings of a similar age were identified for the study. Both groups were examined for dental caries, gingivitis and enamel defects. There was no statistically significant difference in the mean DMFS of the test and control groups. However, the LTS had a significantly (P = 0.006) higher number of decayed surfaces (1.50 +/- 0.30) as compared with their siblings (0.50 +/- 0.20). The LTS also had a significantly higher prevalence of severe gingivitis (1.11 +/- 0.33) compared with controls (0.02 +/- 0.02). There was a significantly higher prevalence of all types of enamel defects in the LTS and fewer teeth with no enamel defect as compared with their siblings, with the mean values being 15.7 +/- 0.9 and 25.3 +/- 0.3, respectively. It was concluded that there was a higher prevalence of untreated dental disease and developmental defects in long-term survivors.
authors.affiliation: Division of Child Dental Health, Leeds Dental Institute, U.K.
authors.forename: M S
authors.initials: MS
authors.lastname: Duggal
authors.forename: M E
authors.initials: ME
authors.lastname: Curzon
authors.forename: C C
authors.initials: CC
authors.lastname: Bailey
authors.forename: I J
authors.initials: IJ
authors.lastname: Lewis
authors.forename: M
authors.initials: M
authors.lastname: Prendergast
mesh_terms: D000293:Adolescent; D000328:Adult; D003731:Dental Caries / Q000209:etiology; D003743:Dental Enamel / Q000002:abnormalities; D003744:Dental Enamel Hypoplasia / Q000209:etiology; D005190:Family; D005500:Follow-Up Studies; D005891:Gingivitis / Q000209:etiology*; D006801:Humans; D009369:Neoplasms / Q000628:therapy*; D017741:Survivors; D014076:Tooth Diseases / Q000209:etiology*