Protoporphyrin derivatives--the use in localization of neoplasmas by titanium laser-induced fluorescence technique.
Examples of in vivo detection of skin neoplasmas (Mercl, melanoma) and breast carcinoma using laser induced fluorescence (LIF) and bis-1[1-alanylo-N]-ethylodeuteroporphyrin (Ala-PP) are described in this study. Photosensitizer, wave titanium laser and standard CCD camera coupled to vision amplifier enable precise neoplasm imaging, Ala-PP retention monitoring and further photodynamic therapy (PDT).
Kwaśny
M
M
Optoelectronics Institute, Technical Military Academy, Warsaw, Poland.
Mierczyk
Z
Z
Fiedor
P
P
Rowiński
W
W
Socha
K
K
Graczyk
A
A
Domaniecki
J
J
Mazurek
A P
AP
D001943:Breast Neoplasms / Q000175:diagnosis*; D002277:Carcinoma / Q000175:diagnosis*; D015266:Carcinoma, Merkel Cell / Q000175:diagnosis; D005260:Female; D006414:Hematoporphyrin Photoradiation; D006801:Humans; D007834:Lasers; D008545:Melanoma / Q000175:diagnosis*; D011524:Protoporphyrins / Q000737:chemistry; D012878:Skin Neoplasms / Q000175:diagnosis*; D013050:Spectrometry, Fluorescence
D011524:Protoporphyrins