[The immunochemical determination of the concentration of organ-specific ejaculate proteins in the differential diagnosis of chronic inflammatory diseases of the male reproductive system].
Concentrations of lactoferrin (LF), alpha-microglobulin of fertility (AMGF) and specific thermostable alpha-glycoprotein (STAG) which are markers of the prostate, seminal vesicles and testiculi in ejaculate, respectively, were determined by Ouchterlony's immunodiffusion method in 148 patients with chronic prostatitis (group 1), 26 patients with combination of prostatitis with chronic epididymitis (group 2) and 22 healthy controls (group 3). After that the patients were given prostatilen. It was found that high pretreatment values of LF registered in groups 1 and 2 lowered close to those in the controls. This shows elevated LF to be a diagnostic sign of prostatitis. In group 1 AMGF was lower than in controls, in groups 1, 2 and 3 STAG levels were similar.
Gal'kovich
K R
KR
Sosnin
D Iu
DIu
D000328:Adult; D015415:Biomarkers / Q000032:analysis; D002908:Chronic Disease; D003937:Diagnosis, Differential; D004542:Ejaculation; D004823:Epididymitis / Q000175:diagnosis*; D006023:Glycoproteins / Q000032:analysis*; D006801:Humans; D007120:Immunochemistry; D005779:Immunodiffusion; D007781:Lactoferrin / Q000032:analysis*; D008297:Male; D011472:Prostatitis / Q000175:diagnosis*; D012661:Semen / Q000737:chemistry*
D015415:Biomarkers; D006023:Glycoproteins; D007781:Lactoferrin