Intractable Crohn's colitis and perianal disease responding to cyclophosphamide and epirubicin.
A case is reported where intractable Crohn's disease responded to chemotherapy for breast carcinoma. The drug most likely responsible was cyclophosphamide. Cyclophosphamide may have a role in the management of inflammatory bowel disease, but this needs to be confirmed before it can be recommended as a treatment option.
Rieger
N
N
Medical Centre, Bedford Park, South Australia.
Stahl
J
J
Wattchow
D
D
D000477:Alkylating Agents / Q000627:therapeutic use*; D000903:Antibiotics, Antineoplastic / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000150:complications / Q000188:drug therapy / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000150:complications / Q000188:drug therapy / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D003092:Colitis / Q000188:drug therapy; D003424:Crohn Disease / Q000150:complications / Q000188:drug therapy*; D003520:Cyclophosphamide / Q000627:therapeutic use*; D015251:Epirubicin / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008408:Mastectomy; D008875:Middle Aged; D012002:Rectal Diseases / Q000188:drug therapy*
D000477:Alkylating Agents; D000903:Antibiotics, Antineoplastic; D007166:Immunosuppressive Agents; D015251:Epirubicin; D003520:Cyclophosphamide