title: Anaesthesiological indications and contraindications of minimally invasive surgery.
abstract: Spreading of laparoscopic techniques caused changes in anaesthesiological contraindications. In the first period laparoscopy was contraindicated in ischemic heart disease (IHD). Early mobilisation and short postoperative period are positive goals, IHD was taken out of contraindications. Present study compares changes in circulatory, blood gas and acid-base balance values during laparoscopic cholecystectomy (LC) in groups of patients ASA I-II. and ASA III. with IHD. There were 30 patients in group ASA I-II, 30 patients with IHD in category of ASA III. investigated during LC. Fifteen patients of both groups went under Propofol-Fentanyl (TIVA) anaesthesia, others were on Propofol-Fentanyl-N2O (IVA) protocol. All of them got also Atracurium. Pulse rate, mean arterial pressure, O2 saturation and end tidal CO2, blood gases and acid-base state were recorded before induction, after CO2 insufflation, after desufflation, 1 and 3 hours postoperatively. After CO2 insufflation there was a moderate tachycardia in both ASA III. groups (74/min-->88/min). In all groups pCO2 increased (40-->48 mmHg) but normalised till the 3rd postoperative hours (42 mmHg). Ventricular extrasystoles appeared in 3 ASA III. patients in IVA group. Three high risk patients had serious metabolic acidosis postoperatively. Present time the ischaemic heart disease does not contraindicates laparoscopic interventions. TIVA with Propofol is better choice because of its favourable effects on circulation and acid-base balance. Using N2O caused higher grade of intestinal distension. The cardio-respiratory, blood gas parameters and acid-base balance have to be monitorised in perioperative period of laparoscopic surgery.
authors.affiliation: 1st Surgical Department, Semmelweis University Medical School, Budapest, Hungary.
authors.forename: K
authors.initials: K
authors.lastname: Darvas
authors.forename: Z
authors.initials: Z
authors.lastname: Molnár
authors.forename: I
authors.initials: I
authors.lastname: Irtó
authors.forename: M
authors.initials: M
authors.lastname: Tarjányi
authors.forename: L
authors.initials: L
authors.lastname: Flautner
mesh_terms: D000136:Acid-Base Equilibrium; D000138:Acidosis / Q000209:etiology; D000768:Anesthesia, General / Q000009:adverse effects / Q000379:methods*; D000769:Anesthesia, Inhalation / Q000009:adverse effects; D000771:Anesthesia, Intravenous / Q000009:adverse effects; D018685:Anesthetics, Inhalation / Q000008:administration & dosage; D018686:Anesthetics, Intravenous / Q000008:administration & dosage; D001279:Atracurium / Q000008:administration & dosage; D001775:Blood Circulation; D001794:Blood Pressure; D002245:Carbon Dioxide / Q000097:blood / Q000378:metabolism; D017081:Cholecystectomy, Laparoscopic / Q000379:methods*; D000075202:Contraindications; D004434:Early Ambulation; D005283:Fentanyl / Q000008:administration & dosage; D005500:Follow-Up Studies; D006801:Humans; D007327:Insufflation; D007431:Intraoperative Complications; D007902:Length of Stay; D019060:Minimally Invasive Surgical Procedures; D017202:Myocardial Ischemia / Q000150:complications*; D003473:Neuromuscular Nondepolarizing Agents / Q000008:administration & dosage; D009609:Nitrous Oxide / Q000008:administration & dosage; D010100:Oxygen / Q000097:blood; D015742:Propofol / Q000008:administration & dosage; D011674:Pulse; D013610:Tachycardia / Q000209:etiology; D018879:Ventricular Premature Complexes / Q000209:etiology
chemical_list: D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D003473:Neuromuscular Nondepolarizing Agents; D002245:Carbon Dioxide; D001279:Atracurium; D009609:Nitrous Oxide; D010100:Oxygen; D005283:Fentanyl; D015742:Propofol