Fundic gland polyps: three other case reports suggesting a possible association with acid suppressing therapy.
We describe three patients who developed fundic gland polyps after starting a treatment with acid suppressive agents. All three patients were treated for a long time with H2-blockers or proton pump inhibiting agents for reflux oesophagitis. In one patient the fundic gland polyps disappeared after discontinuation of the acid suppressing therapy. A possible causal role of these agents is suggested. A review of the literature about fundic gland polyps and their possible association with acid suppressive therapy and a short review about proton pump inhibiting agents and the appearance of gastric polyps in general is given.
Van Vlierberghe
H
H
University Hospital, Department of Gastroenterology, Ghent, Belgium.
De Vos
M
M
De Cock
G
G
Cuvelier
C
C
Elewaut
A
A
D000368:Aged; D000369:Aged, 80 and over; D000897:Anti-Ulcer Agents / Q000009:adverse effects* / Q000627:therapeutic use; D004942:Esophagitis, Peptic / Q000175:diagnosis / Q000188:drug therapy*; D004945:Esophagoscopy; D005260:Female; D018662:Fundoplication; D005744:Gastric Acid / Q000378:metabolism; D005748:Gastric Fundus / Q000473:pathology; D005773:Gastroscopy; D006801:Humans; D008297:Male; D009853:Omeprazole / Q000009:adverse effects* / Q000627:therapeutic use; D011127:Polyps / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery; D011899:Ranitidine / Q000009:adverse effects* / Q000627:therapeutic use; D013274:Stomach Neoplasms / Q000139:chemically induced* / Q000473:pathology / Q000601:surgery
D000897:Anti-Ulcer Agents; D011899:Ranitidine; D009853:Omeprazole