title: Analysis of the metal content of in vivo-fixed dental alloys by means of a simple office procedure.
abstract: The purpose of this study was to devise a simple technique to analyse the metal content of permanent dental prostheses without damaging the constructions. Metal debris was collected on grinding wheels for subsequent analysis by energy-dispersive X-ray fluorescence (EDXRF). We discuss the importance of being able to qualitatively ascertain the composition of the alloys, as such information makes it possible to perform a detailed allergological investigation. Furthermore, we tentatively put our findings in a broader context with regard to the emerging knowledge of the relationship between the immune and central nervous systems as well as the known fact that certain metal ions can produce various cutaneous reactions.
authors.affiliation: Department of Neuroscience, Karolinska Institute, Stockholm, Sweden.
authors.forename: M
authors.initials: M
authors.lastname: Forsell
authors.forename: J A
authors.initials: JA
authors.lastname: Marcusson
authors.forename: B
authors.initials: B
authors.lastname: Carlmark
authors.forename: O
authors.initials: O
authors.lastname: Johansson
mesh_terms: D000328:Adult; D000485:Allergens / Q000009:adverse effects; D003442:Crowns; D003722:Dental Alloys / Q000009:adverse effects / Q000032:analysis*; D003775:Dental Polishing / Q000295:instrumentation; D003793:Dental Restoration, Permanent; D003830:Denture, Partial, Fixed; D003877:Dermatitis, Contact / Q000175:diagnosis / Q000209:etiology; D004485:Eczema / Q000175:diagnosis / Q000209:etiology; D004577:Electron Probe Microanalysis; D005260:Female; D006047:Gold Alloys / Q000009:adverse effects / Q000032:analysis; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000209:etiology; D008670:Metals / Q000009:adverse effects / Q000032:analysis*; D008875:Middle Aged; D009532:Nickel / Q000009:adverse effects / Q000032:analysis; D010165:Palladium / Q000009:adverse effects / Q000032:analysis; D011537:Pruritus / Q000175:diagnosis / Q000209:etiology
chemical_list: D000485:Allergens; D003722:Dental Alloys; D006047:Gold Alloys; D008670:Metals; D010165:Palladium; D009532:Nickel