title: Complete hydatidiform mole and coexisting normal fetuses. A report of two cases with contrasting outcomes.
abstract: BACKGROUND
  Multiple pregnancies consisting of a complete hydatidiform mole and coexisting fetuses are relatively rare but may become more common due to the increasing use of ovulation-induction agents.
  
  
  METHODS
  We report on a twin and a triplet pregnancy, conceived using clomiphene citrate, with contrasting outcomes. The twin pregnancy resulted in a term delivery of a healthy singleton and the triplet pregnancy in a termination at 17 weeks followed by the development of choriocarcinoma.
  
  
  CONCLUSIONS
  The few cases available suggest that a subgroup of complete moles follows a more benign course and can be managed conservatively, allowing the pregnancy to go to term with appropriate follow-up, whereas other cases follow a more aggressive course. Larger case series are needed to develop definitive protocols.
authors.affiliation: Department of Obstetrics and Gynecology, Erasme Hospital, Free University of Brussels, Belgium.
authors.forename: S
authors.initials: S
authors.lastname: Shahabi
authors.forename: G
authors.initials: G
authors.lastname: Naome
authors.forename: L
authors.initials: L
authors.lastname: Cobin
authors.forename: A
authors.initials: A
authors.lastname: Verougstraete
authors.forename: L
authors.initials: L
authors.lastname: Masters
authors.forename: V
authors.initials: V
authors.lastname: Zengbe
authors.forename: J C
authors.initials: JC
authors.lastname: Noël
authors.forename: E F
authors.initials: EF
authors.lastname: Avni
authors.forename: C
authors.initials: C
authors.lastname: Donner
authors.forename: A
authors.initials: A
authors.lastname: Verhest
authors.forename: W
authors.initials: W
authors.lastname: Foulon
authors.forename: F
authors.initials: F
authors.lastname: Rodesch
mesh_terms: D000328:Adult; D002822:Choriocarcinoma; D006063:Chorionic Gonadotropin / Q000097:blood; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000175:diagnosis / Q000503:physiopathology; D011247:Pregnancy; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple; D014594:Uterine Neoplasms
chemical_list: D006063:Chorionic Gonadotropin