Dose depending effect of the complex action hemocorrector "Lactosorbal" on the motility of the distal colon in the paralitic ileus dogs.
For the model of paralytic ileus caused by the severe surgery it has been studied the influence of different doses of hemocorrector of "Lactosorbal" on distal colon motility. It has been established that stimulating effect of "Lactosorbal" on the motility of distal colon is of the dose-dependent nature. The results of the current survey are making the ground for multiple use of "Lactosorbal" to reach the most beneficial outcome of severe paralytic ileus resulting from major traumatic surgery in clinic.
Oborin
A
A
Research Institute of Hematology Medical University, Lvov, Ukraine.
Ivankiv
T
T
Pavlovsky
M
M
Drapaka
V
V
Uspensky
B
B
D000818:Animals; D001802:Blood Substitutes / Q000008:administration & dosage / Q000627:therapeutic use*; D003106:Colon / Q000187:drug effects*; D003108:Colonic Diseases / Q000209:etiology / Q000503:physiopathology*; D004195:Disease Models, Animal; D004285:Dogs; D004305:Dose-Response Relationship, Drug; D005768:Gastrointestinal Hormones / Q000008:administration & dosage / Q000627:therapeutic use; D005769:Gastrointestinal Motility / Q000187:drug effects*; D007275:Injections, Intravenous; D007418:Intestinal Pseudo-Obstruction / Q000209:etiology / Q000503:physiopathology*; D010455:Peptides / Q000008:administration & dosage / Q000627:therapeutic use; D012709:Serum Albumin / Q000008:administration & dosage / Q000627:therapeutic use*; D013011:Sorbic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D013514:Surgical Procedures, Operative / Q000009:adverse effects; D016896:Treatment Outcome
D001802:Blood Substitutes; D005768:Gastrointestinal Hormones; D010455:Peptides; D012709:Serum Albumin; C091503:lactosorbal; C009664:villikinin; D013011:Sorbic Acid