title: Polarized light photography enhances visualization of inflammatory lesions of acne vulgaris.
abstract: BACKGROUND
  Polarized light photography has been used to selectively differentiate surface from subsurface features of photoaged skin.
  
  
  OBJECTIVE
  Our purpose was to compare acne assessments obtained from clinical evaluations with assessments from photographs obtained with flash photography and with perpendicular polarized light photography.
  
  
  METHODS
  Assessments of acne with the Cunliffe scale were made of 32 subjects. Retrospective evaluations of standard and perpendicular polarized light photographs were made in a blinded fashion by a panel of evaluators.
  
  
  RESULTS
  Visualization of inflammatory acne lesions was enhanced with perpendicular polarized light photography, with clear delineation of erythematous borders. Acne assessments with the use of a Cunliffe scale were significantly higher (p = 0.001) from perpendicular polarized light photographs than for clinical evaluations.
  
  
  CONCLUSIONS
  Polarized light photography enhances visualization of inflammatory acne lesions in a manner not possible with conventional flash photographs, permitting accurate evaluation of the extent of disease and the effectiveness of therapy.
authors.affiliation: Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA.
authors.forename: S B
authors.initials: SB
authors.lastname: Phillips
authors.forename: N
authors.initials: N
authors.lastname: Kollias
authors.forename: R
authors.initials: R
authors.lastname: Gillies
authors.forename: J A
authors.initials: JA
authors.lastname: Muccini
authors.forename: L A
authors.initials: LA
authors.lastname: Drake
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy / Q000473:pathology*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002981:Clindamycin / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use; D004890:Erythema / Q000473:pathology; D005069:Evaluation Studies as Topic; D005148:Facial Dermatoses / Q000188:drug therapy / Q000473:pathology; D005500:Follow-Up Studies; D006801:Humans; D017495:Hyperpigmentation / Q000473:pathology; D007249:Inflammation / Q000473:pathology; D008027:Light; D010781:Photography / Q000379:methods*; D012189:Retrospective Studies; D016037:Single-Blind Method; D012867:Skin / Q000473:pathology; D015595:Skin Aging
chemical_list: D000900:Anti-Bacterial Agents; D003879:Dermatologic Agents; D002981:Clindamycin