title: Paradoxic excitation with diphenhydramine in an adult.
abstract: Although paradoxic excitation may rarely occur in children and adults with conventional dosages of antihistamines, few case reports have appeared in the literature. We cared for a 46-year-old patient who became extremely agitated after receiving a dose of intravenous diphenhydramine.
authors.affiliation: Department of Pharmacy, Bassett Healthcare, Cooperstown, New York 13326, USA.
authors.forename: K L
authors.initials: KL
authors.lastname: Cheng
authors.forename: P N
authors.initials: PN
authors.lastname: Dwyer
authors.forename: G W
authors.initials: GW
authors.lastname: Amsden
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000150:complications / Q000628:therapy; D004155:Diphenhydramine / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006634:Histamine H1 Antagonists / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008875:Middle Aged; D011595:Psychomotor Agitation / Q000503:physiopathology*
chemical_list: D006634:Histamine H1 Antagonists; D004155:Diphenhydramine