title: Cavernous angiomas of the spinal district: surgical treatment of 11 patients.
abstract: Cavernous angiomas, also called cavernous malformations or cavernomas, are vascular hamartomas accounting for 3-16% of all angiomatous lesions of the spinal district. Although histologically identical, these vascular anomalies may exhibit different clinical behavior and radiological features, depending on their location, hinting at different managements and therapeutic approaches. The authors report 11 cases of symptomatic spinal cavernous angiomas diagnosed and surgically treated over the past 18 years. Age of patients ranged from 15-75 years; males outnumbered females. Three patients had vertebral cavernous malformations, secondarily invading the epidural space; two had pure epidural lesions; two patients had intradural extramedullary lesions, and four intramedullary lesions. Surgical removal was completely achieved in four patients with intramedullary lesions, in two with subdural extramedullary lesions, and in one with a pure epidural lesion. Subtotal excision of another one epidural and three vertebral cavernous angiomas was followed by radiotherapy. There was no morbidity related to surgery; the mean follow-up was 2 years. The outcome was excellent in two cases, good in six, and unchanged in the other three. The authors discuss the different modalities of treatment of these vascular lesions variously placed along the spine.
authors.affiliation: Department of Neurosurgery, Bellaria Hospital, Bologna, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Padovani
authors.forename: N
authors.initials: N
authors.lastname: Acciarri
authors.forename: M
authors.initials: M
authors.lastname: Giulioni
authors.forename: R
authors.initials: R
authors.lastname: Pantieri
authors.forename: M P
authors.initials: MP
authors.lastname: Foschini
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002574:Cervical Vertebrae; D005260:Female; D005500:Follow-Up Studies; D006392:Hemangioma, Cavernous / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D006801:Humans; D007796:Laminectomy; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D013120:Spinal Cord Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D013125:Spinal Neoplasms / Q000175:diagnosis / Q000532:radiotherapy / Q000601:surgery*; D013904:Thoracic Vertebrae; D014057:Tomography, X-Ray Computed