Abscisic acid signaling through cyclic ADP-ribose in plants.
Abscisic acid (ABA) is the primary hormone that mediates plant responses to stresses such as cold, drought, and salinity. Single-cell microinjection experiments in tomato were used to identify possible intermediates involved in ABA signal transduction. Cyclic ADP-ribose (cADPR) was identified as a signaling molecule in the ABA response and was shown to exert its effects by way of calcium. Bioassay experiments showed that the amounts of cADPR in Arabidopsis thaliana plants increased in response to ABA treatment and before ABA-induced gene expression.
Wu
Y
Y
Laboratory of Plant Molecular Biology, Rockefeller University, 1230 York Avenue, New York, NY 10021-6399, USA.
Kuzma
J
J
Maréchal
E
E
Graeff
R
R
Lee
H C
HC
Foster
R
R
Chua
N H
NH
D000040:Abscisic Acid / Q000494:pharmacology*; D000246:Adenosine Diphosphate Ribose / Q000031:analogs & derivatives* / Q000378:metabolism / Q000494:pharmacology; D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism; D029681:Arabidopsis Proteins; D002118:Calcium / Q000378:metabolism* / Q000494:pharmacology; D036563:Cyclic ADP-Ribose; D004533:Egtazic Acid / Q000494:pharmacology; D019204:GTP-Binding Proteins / Q000502:physiology; D018506:Gene Expression Regulation, Plant / Q000187:drug effects; D017930:Genes, Reporter; D007295:Inositol Phosphates / Q000494:pharmacology; D018551:Solanum lycopersicum / Q000235:genetics / Q000378:metabolism; D008845:Microinjections; D010749:Phosphoprotein Phosphatases / Q000378:metabolism; D010766:Phosphorylation; D010834:Phytochrome / Q000494:pharmacology; D051942:Phytochrome A; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D030821:Plants, Genetically Modified; D011494:Protein Kinases / Q000378:metabolism; D015290:Second Messenger Systems; D015398:Signal Transduction
D029681:Arabidopsis Proteins; D007295:Inositol Phosphates; C497973:PHYA protein, Arabidopsis; D051942:Phytochrome A; D010834:Phytochrome; D036563:Cyclic ADP-Ribose; D000246:Adenosine Diphosphate Ribose; D004533:Egtazic Acid; D000040:Abscisic Acid; D011494:Protein Kinases; D010749:Phosphoprotein Phosphatases; D019204:GTP-Binding Proteins; D002118:Calcium