title: Isolated sphenoid sinus aspergillomas.
abstract: Fungi are more often than previously believed to be the causative organisms of paranasal sinusitis. Aspergillus, a fungus belonging to the Ascomycetes class, accounts for the majority of these infections, which affect not only debilitated patients but healthy people as well. There are two distinct clinical forms of Aspergillus sinusitis, invasive and non-invasive, and each of them is further divided in two subtypes. Isolated aspergillosis of the sphenoid sinus is a rare disease, which is usually misdiagnosed for a long time because of its varying symptomatology. In the present study, four cases of isolated sphenoid Aspergillus disease are described and the recent literature is reviewed. Physicians should be aware of this rare clinical entity, as in many cases early diagnosis and appropriate treatment provide the key to achieve favourable outcomes.
authors.affiliation: ENT Department, University of Athens School of Medicine, Hippokration Hospital, Greece.
authors.forename: I
authors.initials: I
authors.lastname: Yiotakis
authors.forename: I
authors.initials: I
authors.lastname: Psarommatis
authors.forename: I
authors.initials: I
authors.lastname: Seggas
authors.forename: L
authors.initials: L
authors.lastname: Manolopoulos
authors.forename: E
authors.initials: E
authors.lastname: Ferekidis
authors.forename: G
authors.initials: G
authors.lastname: Adamopoulos
mesh_terms: D000328:Adult; D000368:Aged; D001228:Aspergillosis / Q000000981:diagnostic imaging / Q000601:surgery; D003131:Combined Modality Therapy; D004724:Endoscopy; D005260:Female; D006801:Humans; D008875:Middle Aged; D015524:Sphenoid Sinusitis / Q000000981:diagnostic imaging / Q000382:microbiology* / Q000601:surgery; D014057:Tomography, X-Ray Computed