title: Role of transient-evoked otoacoustic emissions for hearing preservation in acoustic neuroma surgery.
abstract: OBJECTIVE
  This study aimed to assess whether transient-evoked otoacoustic emissions (TEOAEs), which are known to be expressions of an intact cochlear function, could be useful for the rationale of hearing preservation in acoustic neuroma (AN) surgery.
  
  
  METHODS
  The TEOAEs were measured before, during, and after surgery in a consecutive series of patients affected by cerebellopontine angle tumors.
  
  
  METHODS
  The study was performed at the Department of Otolaryngology, University "La Sapienza" of Rome.
  
  
  METHODS
  Five patients with AN and one with a meningioma totally involving the Cochlear (VIII) nerve.
  
  
  METHODS
  Retrosigmoid approach on the ground of the limited AN size (within 20 mm) and the 30/70 rule, as proposed by the American Academy of Otolaryngology-Head and Neck Surgery nomogram. Two patients also were selected despite a poor hearing level and the absence of TEOAEs.
  
  
  METHODS
  Preoperative and postoperative pure tone audiometry compared with TEOAEs. Intraoperative TEOAEs were compared with electrocochleographic findings.
  
  
  RESULTS
  The TEOAEs were found to be present also in patients with AN with poor pure-tone average (PTA) threshold (i.e., > 75 dB). Intraoperatively, TEOAEs recording showed to be markedly affected by the environmental noise as well as by specific intraoperative maneuvers, such as drilling of the internal auditory canal or tumor removal or both. In the three patients in whom hearing successfully was preserved. TEOAEs were present in the first postoperative days, despite a temporary deterioration of the PTA threshold.
  
  
  CONCLUSIONS
  The intraoperative use of TEOAEs showed to be scarcely reliable, whereas their presence in the preoperative assessment of patients with AN could lead to an extended number of patients to be selected for hearing-preservation surgery. Finally, an early postoperative identification of TEOAEs may be considered a favorable prognostic sign for foreseeing a delayed pure-tone hearing threshold recovery.
authors.affiliation: Department of Otolaryngology, University of Rome La Sapienza, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Filipo
authors.forename: R
authors.initials: R
authors.lastname: Delfini
authors.forename: M
authors.initials: M
authors.lastname: Fabiani
authors.forename: A
authors.initials: A
authors.lastname: Cordier
authors.forename: M
authors.initials: M
authors.lastname: Barbara
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D000368:Aged; D001300:Audiometry, Evoked Response; D001301:Audiometry, Pure-Tone; D001309:Auditory Threshold; D003051:Cochlea; D005260:Female; D006309:Hearing / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009464:Neuroma, Acoustic / Q000601:surgery*