title: Straight ileoanal anastomosis with multiple ileal myotomies as an alternative to pelvic pouch.
abstract: An alternative technique of restorative proctocolectomy, by means of straight ileoanal anastomosis with multiple myotomies (SIAM) of the terminal ileum in 15 patients, nine with familial adenomatous polyposis (FAP) and six with ulcerative colitis (UC) is reported.
  
  
  METHODS
  Eight to ten longitudinal myotomies (3-4 cm long, on three different circumferential sites) were performed on the terminal ileum for a total length of 12-14 cm.
  
  
  RESULTS
  At a mean follow up of 44 months (range 3-84 months) from the closure of the ileostomy, daytime continence was achieved in all the patients; stool frequency per 24 hours (+/- SD) was 4.1 +/- 1.8 for FAP patients and 5.8 +/- 1.7 for UC patients; nocturnal defecation was 1.0 +/- 0.5 and 1.2 +/- 0.8 for FAP and UC patients respectively; frequent nocturnal soiling was present in 2/5 of UC patients, and in 3/9 of FAP patients. SIAM failed in one UC patient that was converted to an ileoanal reservoir because of poor functional result. Signs of ileal mucosal inflammation were never observed at endoscopic examination. Histopathological assessment showed no evidence of acute terminal ileitis. MANOMETRIC FINDINGS: A significant postoperative reduction in anal resting pressure was observed after SIAM. Neither the absence of anal inhibitory reflex nor the presence of high pressure waves generated in the terminal ileum during air insufflation were related to the presence of soiling. The closure of the loop ileostomy was followed by an increased capacity and distensibility of the terminal ileum. Values of neorectal compliance were similar in FAP and UC patients although FAP patients were able to reach higher values of maximum tolerated volume and pressure.
  
  
  CONCLUSIONS
  1) SIAM can be an alternative to pelvic pouch in patients who have undergone restorative proctocolectomy when the construction of the pouch is not feasible. 2) The functional result observed after SIAM has been shown to be similar to that observed after pouch construction.
authors.affiliation: Department of Clinical Physiopathology, University of Florence, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Tonelli
authors.forename: G
authors.initials: G
authors.lastname: Batignani
authors.forename: F
authors.initials: F
authors.lastname: Ficari
authors.forename: P
authors.initials: P
authors.lastname: Mazzoni
authors.forename: A
authors.initials: A
authors.lastname: Garcea
authors.forename: I
authors.initials: I
authors.lastname: Monaci
mesh_terms: D018256:Adenomatous Polyps / Q000601:surgery*; D000293:Adolescent; D000328:Adult; D001003:Anal Canal / Q000502:physiology / Q000601:surgery*; D000714:Anastomosis, Surgical / Q000379:methods; D002648:Child; D003093:Colitis, Ulcerative / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007082:Ileum / Q000502:physiology / Q000601:surgery*; D008297:Male; D008365:Manometry; D008875:Middle Aged; D009130:Muscle, Smooth / Q000502:physiology / Q000601:surgery*; D016737:Proctocolectomy, Restorative / Q000379:methods*