Mechanisms of limited maximum coronary flow in severe single-vessel coronary artery disease in humans due to vertical steal.
We evaluated the usefulness of a decrease in the average peak velocity from 4 to 10 minutes after infusion of dipyridamole for detecting myocardial ischemia in 50 patients, including patients with a prior myocardial infarction. The decrease in the average peak velocity from 4 to 10 minutes associated with vertical steal and combined with a coronary flow reserve of < 1.6 had a high predictive value for myocardial ischemia in patients with or without prior myocardial infarction.
Hamasaki
S
S
First Department of Internal Medicine, Faculty of Medicine, Kagoshima University, Japan.
Arima
S
S
Fukumoto
N
N
Yamaguchi
T
T
Nakano
F
F
Kamekou
M
M
Kihara
K
K
Shono
H
H
Nakao
S
S
Tanaka
H
H
D000368:Aged; D001783:Blood Flow Velocity / Q000187:drug effects; D003326:Coronary Circulation; D004176:Dipyridamole / Q000494:pharmacology; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology; D017202:Myocardial Ischemia / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000503:physiopathology; D011237:Predictive Value of Tests; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D013794:Thallium Radioisotopes; D014665:Vasodilator Agents / Q000494:pharmacology
D013794:Thallium Radioisotopes; D014665:Vasodilator Agents; D004176:Dipyridamole