title: Cinemakeratography using computer morphing.
abstract: OBJECTIVE
  TMS-1 videokeratography (Tomey Technologies, Inc.) was animated using computer morphing to visualize corneal shape change over time.
  
  
  METHODS
  Morphing was performed using keratoconus (8 examinations/76 months) and postoperative photorefractive keratectomy (PRK) corneas (8 examinations/37 months; LSU PRK Phase IIa).
  
  
  RESULTS
  In the keratoconus animation, the inferior cone increased curvature, but not equally in all directions, nor at a constant rate. The cone apex did not drift over time. Periodic flattening and steepening was observed superiorly, as well as cone regression at month 76. The Keratoconus Prediction Index (KPI) at month 0 was 0.18, plateaued at 0.36 at month 46, and dropped to 0.33 at month 76. In the post-PRK animation there was continuous corneal remodeling out to 30 months. Fluctuating steep and flat regions of the ablation zone correlated with the Surface Regularity Index (SRI).
  
  
  CONCLUSIONS
  Cinemakeratography (Cinema-K) enhanced our appreciation of subtle changes in corneal topography.
authors.affiliation: Lions Eye Research Laboratories, LSU Eye Center, Louisiana State University Medical Center, New Orleans, USA. msmole@lsumc.edu
authors.forename: M K
authors.initials: MK
authors.lastname: Smolek
authors.forename: S D
authors.initials: SD
authors.lastname: Klyce
mesh_terms: D003315:Cornea / Q000033:anatomy & histology* / Q000473:pathology; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007640:Keratoconus / Q000473:pathology; D054018:Lasers, Excimer; D009040:Motion Pictures; D018903:Photorefractive Keratectomy; D011184:Postoperative Period