title: Iris-color change developed after topical isopropyl unoprostone treatment.
abstract: OBJECTIVE
  To present a case in which iris pigmentation developed after treatment with isopropyl unoprostone, an analogue of a prostaglandin metabolite.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  A Japanese man with dark brown irises, treated unilaterally with isopropyl unoprostone, developed iris-color change in the treated eye after a 20-month treatment.
  
  
  CONCLUSIONS
  Isopropyl unoprostone can induce iris pigmentation as does latanoprost.
authors.affiliation: Department of Ophthalmology, Gifu University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yamamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Kitazawa
mesh_terms: D000287:Administration, Topical; D015237:Dinoprost / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005127:Eye Color / Q000187:drug effects*; D005500:Follow-Up Studies; D005901:Glaucoma / Q000188:drug therapy; D006801:Humans; D007498:Iris / Q000187:drug effects* / Q000473:pathology; D007499:Iris Diseases / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions
chemical_list: D009883:Ophthalmic Solutions; C072630:isopropyl unoprostone; D015237:Dinoprost