Lymphocytes with cerebriform nuclei in chronic B-cell lymphoproliferative diseases.
Two patients with chronic lymphoproliferative diseases, a splenic marginal zone lymphoma and hairy cell leukaemia variant, were reported. In both diseases a B-immunophenotype was demonstrated but a variable percentage of lymphoid cells (30 and 52%) showed a highly irregular nuclear outline, sometimes mimicking the nuclei of Sézary cells.
Woessner
S
S
Hospital Central l'Aliança, Barcelona, Spain.
Domingo
A
A
Gumà
J
J
Romagosa
V
V
Florensa
L
L
D000368:Aged; D001402:B-Lymphocytes / Q000473:pathology*; D014408:Biomarkers, Tumor / Q000032:analysis; D002467:Cell Nucleus / Q000648:ultrastructure*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007943:Leukemia, Hairy Cell / Q000473:pathology / Q000601:surgery; D008232:Lymphoproliferative Disorders / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged; D012751:Sezary Syndrome / Q000175:diagnosis / Q000473:pathology*; D013156:Splenectomy
D014408:Biomarkers, Tumor