title: Indocyanine green angiographic findings in multifocal choroidopathies.
abstract: With high definition videoangiography (TOPCON IMAGEnet H1024) the Authors studied 41 patients affected by multifocal choroidopathies (MC) (68 eyes with ophthalmoscopic or indocyanine green angiographic evidences): 29 females and 12 males; age 21-51 years with a follow up of 6-29 months. In the light of the evidence provided by FA and ICG the Authors present a classification of MC in three stages: Stage 1 of subclinical choroidal activity (5 eyes): characterised by the presence of hypofluorescent or hyperfluorescent spots visible only in the late phases of ICGA; stage 2 of clinically evident choroidal activity (45 eyes): in FA the spots are hypofluorescent in the early phases and hyperfluorescent with a slight diffusion in the late phases, in ICGA either hypofluorescent spots or less frequently hyperfluorescent spots and choroidal permeability alterations can be observed; stage 3 or healed stage (18 eyes): in FA the spots are hyperfluorescent without late leakage, in ICGA hypofluorescence can be observed during all angiographic phases. In 5 patients in stage 1 of subclinical activity, a systemic steroid therapy induced the regression of the hypofluorescent sports in ICGA, in 2 cases the regression of hyperfluorescent spots in ICGA was observed after systemic antibiotic therapy. The authors underline that ICGA could be a particularly useful tool for an early diagnosis and clinical monitoring of MC.
authors.affiliation: Clinica Oculistica dell'Università di Ancona, Nuovo Ospedale Regionale di Torrette, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Giovannini
authors.forename: B
authors.initials: B
authors.lastname: Scassellati Sforzolini
authors.forename: E
authors.initials: E
authors.lastname: D'altobrando
authors.forename: C
authors.initials: C
authors.lastname: Mariotti
mesh_terms: D000328:Adult; D015862:Choroid Diseases / Q000145:classification / Q000175:diagnosis*; D004396:Coloring Agents; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008875:Middle Aged; D014792:Visual Acuity
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green