title: Fine needle aspiration biopsy in children.
abstract: BACKGROUND
  Fine needle biopsy (FNB) in children has been slow to gain acceptance compared with the use of the technique in adults where it is regarded as standard clinical practice in screening significant lymphadenopathy and suspicious masses. We report our early experience with FNB in the paediatric population.
  
  
  METHODS
  Fifty-two biopsies were performed between June 1991 and June 1993. The age of the children ranged from 6 months to 14 years (median 2 years, mean 5 years).
  
  
  RESULTS
  A definite diagnosis on cytology alone was obtained in 67%. The pathologist was certain of malignant or nonmalignant potential in 79% (67% benign and 12% malignant) and unsure in 21% (17% benign and 4% malignant). There were no false positive or false negative diagnoses of malignancy. Surgical excision or biopsy was performed in 33%. Fine needle biopsy assisted in planning surgery in 12%. Surgery was necessary for a definite diagnosis in 21% and FNB assisted 42% of the patients to avoid surgery altogether.
  
  
  CONCLUSIONS
  Fine needle biopsy is simple, minimally invasive and useful in the evaluation of children with suspicious lymph nodes and masses.
authors.affiliation: Division of Surgery, Princess Margaret Hospital for Children, Perth, Western Australia.
authors.forename: J E
authors.initials: JE
authors.lastname: Orford
authors.forename: I
authors.initials: I
authors.lastname: Gollow
authors.forename: B
authors.initials: B
authors.lastname: Brennan
authors.forename: L
authors.initials: L
authors.lastname: Hallam
mesh_terms: D000293:Adolescent; D001707:Biopsy, Needle; D002648:Child; D002675:Child, Preschool; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D007223:Infant; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D009369:Neoplasms / Q000473:pathology*; D011237:Predictive Value of Tests; D015203:Reproducibility of Results