title: Computer-assisted adjustment of inspired oxygen concentration improves control of oxygen saturation in newborn infants requiring mechanical ventilation.
abstract: Open-loop computer control of inspired oxygen concentration was evaluated in 16 newborn infants requiring mechanical ventilation. FIO2 and oxygen saturation were compared for 2-hour periods of computer versus routine manual FIO2 adjustment. During computer-assisted FIO2 adjustment, patients spent more time at the target SaO2 and less time with SaO2 < 90%.
authors.affiliation: Joint Program in Neonatology, Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Sun
authors.forename: I S
authors.initials: IS
authors.lastname: Kohane
authors.forename: A R
authors.initials: AR
authors.lastname: Stark
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D010092:Oximetry; D010101:Oxygen Consumption; D012121:Respiration, Artificial; D013813:Therapy, Computer-Assisted