Blood clozapine levels elevated by fluvoxamine: potential for side effects and lower clozapine dosage.
Armstrong
S C
SC
Stephans
J R
JR
D000328:Adult; D003024:Clozapine / Q000097:blood* / Q000493:pharmacokinetics / Q000627:therapeutic use; D019388:Cytochrome P-450 CYP1A2 / Q000187:drug effects; D065609:Cytochrome P-450 CYP1A2 Inhibitors; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System / Q000187:drug effects; D004334:Drug Administration Schedule; D004359:Drug Therapy, Combination; D005260:Female; D016666:Fluvoxamine / Q000009:adverse effects / Q000493:pharmacokinetics* / Q000627:therapeutic use; D006801:Humans; D008862:Microsomes, Liver / Q000187:drug effects; D011618:Psychotic Disorders / Q000188:drug therapy
D065609:Cytochrome P-450 CYP1A2 Inhibitors; D065607:Cytochrome P-450 Enzyme Inhibitors; D003577:Cytochrome P-450 Enzyme System; D019388:Cytochrome P-450 CYP1A2; D003024:Clozapine; D016666:Fluvoxamine