title: Marfan Database (third edition): new mutations and new routines for the software.
abstract: The Marfan database is a software that contains routines for the analysis of mutations identified in the FBN1 gene that encodes fibrillin-1. Mutations in this gene are associated not only with Marfan syndrome but also with a spectrum of overlapping disorders. The third version of the Marfan database contains 137 entries. The software has been modified to accommodate four new routines and is now accessible on the World Wide Web at http://www.umd.necker.fr
authors.affiliation: INSERM U383, Hôpital Necker-Enfants Malades, Université René Descartes, Paris V, 149-161 rue de Sèvres, 75743 Paris Cedex 15, France.
authors.forename: G
authors.initials: G
authors.lastname: Collod-Béroud
authors.forename: C
authors.initials: C
authors.lastname: Béroud
authors.forename: L
authors.initials: L
authors.lastname: Ades
authors.forename: C
authors.initials: C
authors.lastname: Black
authors.forename: M
authors.initials: M
authors.lastname: Boxer
authors.forename: D J
authors.initials: DJ
authors.lastname: Brock
authors.forename: K J
authors.initials: KJ
authors.lastname: Holman
authors.forename: A
authors.initials: A
authors.lastname: de Paepe
authors.forename: U
authors.initials: U
authors.lastname: Francke
authors.forename: U
authors.initials: U
authors.lastname: Grau
authors.forename: C
authors.initials: C
authors.lastname: Hayward
authors.forename: H G
authors.initials: HG
authors.lastname: Klein
authors.forename: W
authors.initials: W
authors.lastname: Liu
authors.forename: L
authors.initials: L
authors.lastname: Nuytinck
authors.forename: L
authors.initials: L
authors.lastname: Peltonen
authors.forename: A B
authors.initials: AB
authors.lastname: Alvarez Perez
authors.forename: T
authors.initials: T
authors.lastname: Rantamäki
authors.forename: C
authors.initials: C
authors.lastname: Junien
authors.forename: C
authors.initials: C
authors.lastname: Boileau
mesh_terms: D003195:Computer Communication Networks; D004252:DNA Mutational Analysis; D016208:Databases, Factual; D000071838:Fibrillin-1; D000071837:Fibrillins; D006801:Humans; D008382:Marfan Syndrome / Q000235:genetics*; D008840:Microfilament Proteins / Q000235:genetics; D009154:Mutation; D012984:Software; D054392:Adipokines
chemical_list: D000071838:Fibrillin-1; D000071837:Fibrillins; D008840:Microfilament Proteins; C000605722:FBN1 protein, human; D054392:Adipokines