title: [Gastroesophageal reflux disease refractory to medical treatment. Which approach: the pill or the scalpel?].
abstract: We analyze the modern literature regarding natural history, clinical picture and treatment of gastroesophageal reflux disease. The characteristics of a small group of patients with tendency to relapse are emphasized, analyzing the possibilities offered by pharmacological as well as surgical treatment. Finally, we analyse the current literature of our country situation.
authors.affiliation: Servicio de Gastroenterología, Hospital Profesor Alejandro Posadas.
authors.forename: J C
authors.initials: JC
authors.lastname: Chiocca
authors.forename: G B
authors.initials: GB
authors.lastname: Salis
mesh_terms: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D001562:Benzimidazoles / Q000627:therapeutic use; D018662:Fundoplication; D005764:Gastroesophageal Reflux / Q000188:drug therapy* / Q000601:surgery*; D006801:Humans; D064747:Lansoprazole; D010535:Laparoscopy; D009853:Omeprazole / Q000031:analogs & derivatives / Q000627:therapeutic use; D000077402:Pantoprazole; D054328:Proton Pump Inhibitors; D012008:Recurrence; D013454:Sulfoxides / Q000627:therapeutic use
chemical_list: D053799:2-Pyridinylmethylsulfinylbenzimidazoles; D001562:Benzimidazoles; D054328:Proton Pump Inhibitors; D013454:Sulfoxides; D064747:Lansoprazole; D000077402:Pantoprazole; D009853:Omeprazole