title: Interference of peptides and specific antibodies with the function of the Actinobacillus pleuropneumoniae transferrin-binding protein.
abstract: Multiple-antigenic peptides (MAPs) containing transferrin-binding domains of the Actinobacillus pleuropneumoniae serotype 7-derived transferrin-binding protein (TfbA) (K. Strutzberg, L. von Olleschik, B. Franz, C. Pyne, M. A. Schmidt, and G.-F. Gerlach, Infect. Immun. 63:3846-3850, 1995) were constructed. It was found that the MAPs inhibited transferrin binding of the recombinant TfbA protein, whereas antibodies directed against transferrin-binding domains failed to do so.
authors.affiliation: Tierärztliche Hochschule Hannover, Institut für Mikrobiologie und Tierseuchen, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Strutzberg
authors.forename: B
authors.initials: B
authors.lastname: Franz
authors.forename: G F
authors.initials: GF
authors.lastname: Gerlach
mesh_terms: D016977:Actinobacillus pleuropneumoniae / Q000378:metabolism*; D000595:Amino Acid Sequence; D000907:Antibodies, Bacterial / Q000276:immunology* / Q000378:metabolism; D001426:Bacterial Proteins / Q000737:chemistry / Q000276:immunology / Q000378:metabolism*; D008969:Molecular Sequence Data; D010455:Peptides / Q000737:chemistry / Q000378:metabolism; D011485:Protein Binding; D014168:Transferrin / Q000378:metabolism*
chemical_list: D000907:Antibodies, Bacterial; D001426:Bacterial Proteins; D010455:Peptides; D014168:Transferrin