title: Tibial insert undersurface as a contributing source of polyethylene wear debris.
abstract: Sixty-seven ultrahigh molecular weight polyethylene tibial inserts from cementless total knee arthroplasties were retrieved at autopsy and revision surgery and analyzed for evidence of articular and nonarticular surface wear after a mean implantation time of 62.8 months (range, 4-131 months). Polyethylene cold flow and abrasive wear on the nonarticular insert surface (undersurface) were assigned a wear severity score (Grade 0-4). The severity of articular wear was assessed quantitatively and graded. Corresponding prerevision radiographs were evaluated for evidence of tibial metaphyseal osteolysis and osteolysis around tibial fixation screws. Exact nonparametric conditional inference methods were used to establish correlations between different variables and the occurrence of tibial metaphyseal osteolysis. Severe Grade 4 wear of the tibial insert undersurface was associated with tibial metaphyseal osteolysis or osteolysis around fixation screws. Time in situ statistically was related to Grade 4 undersurface wear and tibial metaphyseal osteolysis. The occurrence of tibial osteolysis was not related statistically to articular wear severity, insert thickness, or implant type. The main articulation between the femoral implant and ultrahigh molecular weight polyethylene insert has been assumed to be the primary source of polyethylene debris contributing to osteolysis and total knee arthroplasty implant failure. The undersurface of the insert is an additional source of polyethylene debris contributing to tibial metaphyseal osteolysis. To lessen polyethylene debris produced at this modular interface, the tibial implant locking mechanism should fix the insert firmly to the metal backing to decrease relative micromotion. Because motion between the insert and metal backing may be inevitable, the wear characteristics of the inner tray surface should be optimized to minimize wear debris production at this other articulation.
authors.affiliation: Biomaterials Laboratory, Ohio State University, Columbus, USA.
authors.forename: R C
authors.initials: RC
authors.lastname: Wasielewski
authors.forename: N
authors.initials: N
authors.lastname: Parks
authors.forename: I
authors.initials: I
authors.lastname: Williams
authors.forename: H
authors.initials: H
authors.lastname: Surprenant
authors.forename: J P
authors.initials: JP
authors.lastname: Collier
authors.forename: G
authors.initials: G
authors.lastname: Engh
mesh_terms: D019645:Arthroplasty, Replacement, Knee; D001863:Bone Screws / Q000009:adverse effects; D005269:Femur / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D007720:Knee Prosthesis / Q000009:adverse effects; D008670:Metals; D008970:Molecular Weight; D009068:Movement; D010014:Osteolysis / Q000000981:diagnostic imaging / Q000209:etiology; D011095:Polyethylenes; D011474:Prosthesis Design; D011475:Prosthesis Failure; D011859:Radiography; D012086:Reoperation; D013314:Stress, Mechanical; D013499:Surface Properties; D013977:Tibia / Q000000981:diagnostic imaging / Q000601:surgery; D013997:Time Factors
chemical_list: D008670:Metals; D011095:Polyethylenes