title: Synthesis and pharmacological properties of 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives.
abstract: Some selected 1-aryl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives were synthesized and evaluated as the beta-adrenoceptor agents. Some of the compounds showed a weak agonistic or antagonistic activity on these receptors.
authors.affiliation: Institute of Chemistry and Technology of Drugs, School of Medicine, Lódź, Poland.
authors.forename: E
authors.initials: E
authors.lastname: Brzezińska
mesh_terms: D000818:Animals; D005260:Female; D006168:Guinea Pigs; D006321:Heart / Q000187:drug effects / Q000502:physiology; D006339:Heart Rate / Q000187:drug effects; D066298:In Vitro Techniques; D007546:Isoquinolines / Q000138:chemical synthesis* / Q000494:pharmacology*; D008297:Male; D009126:Muscle Relaxation; D011943:Receptors, Adrenergic, beta / Q000187:drug effects*; D014132:Trachea / Q000187:drug effects / Q000502:physiology
chemical_list: D007546:Isoquinolines; D011943:Receptors, Adrenergic, beta