title: [Behavior reactions and lipids of brain synaptic membranes of rats under chronic exposure to gamma irradiation].
abstract: The effects of low level chronic ionising irradiation (12.9 cGy/day on the sensory attention to the stimuli of different modalities (somatosensory, visual, odor) of Wistar rats were studied. Analysis of animals behaviour was made after they had received the different doses of irradiation: 4, 6, 8, 10, 15 and 20 Gy. It was founded, that the attention and exploratory activity of rats is significantly decreased up to 20-30% after 4-6 Gy. The irradiation doses 8 Gy did not change animal behaviour as compared to control animals, but doses 10, 15 and 20 Gy decreased the exploratory activity as well as sensory attention of rats to 3-5-times as compared to previous dose. Such a wave-like way of behaviour reflects the functioning of an adaptive mechanism. Biochemical data indicated that after 5 months of the irradiation (dose 20 Gy) the level of phospholipids, lysophosphatidylcholine, phosphatidylethanolamine, phosphatidylcholine, cholesterol were decreased.
authors.forename: T P
authors.initials: TP
authors.lastname: Semenova
authors.forename: N I
authors.initials: NI
authors.lastname: Medvinskaia
authors.forename: N I
authors.initials: NI
authors.lastname: Potekhina
authors.forename: I K
authors.initials: IK
authors.lastname: Kolomiĭtseva
mesh_terms: D000818:Animals; D001288:Attention / Q000528:radiation effects; D001522:Behavior, Animal / Q000528:radiation effects*; D001921:Brain / Q000378:metabolism / Q000528:radiation effects*; D002784:Cholesterol / Q000032:analysis / Q000528:radiation effects; D002855:Chromatography, Thin Layer; D003627:Data Interpretation, Statistical; D005106:Exploratory Behavior / Q000528:radiation effects; D005720:Gamma Rays; D008244:Lysophosphatidylcholines / Q000032:analysis / Q000528:radiation effects; D008297:Male; D008563:Membrane Lipids / Q000032:analysis / Q000528:radiation effects*; D010714:Phosphatidylethanolamines / Q000032:analysis / Q000528:radiation effects; D010743:Phospholipids / Q000032:analysis / Q000528:radiation effects; D011829:Radiation Dosage; D051381:Rats; D017208:Rats, Wistar; D013570:Synaptic Membranes / Q000378:metabolism / Q000528:radiation effects*; D013997:Time Factors
chemical_list: D008244:Lysophosphatidylcholines; D008563:Membrane Lipids; D010714:Phosphatidylethanolamines; D010743:Phospholipids; D002784:Cholesterol