title: Necrotizing granulomatosis of the breast.
abstract: We describe a case of necrotizing granulomatosis of Wegener's type involving the breasts of a 40-year-old man. There were no signs of generalized disease. Involvement of the breast is rare in Wegener's granulomatosis (WG). To date, 17 cases have been reported, and all were women. They predominantly presented with a unilateral breast mass, and mammary malignancy was the principal concern. In the majority of cases, breast lesions of WG have been a presenting sign of, or preceded, disseminated disease. Our patient is unusual in that the necrotizing granulomas developed as an isolated finding in a site remote from those usually affected by WG, and, as far as we are aware, represents the first case of Wegener's type granulomatosis involving the male breast.
authors.affiliation: Department of Dermatology, University Hospital of Zurich, Switzerland.
authors.forename: R M
authors.initials: RM
authors.lastname: Trüeb
authors.forename: M
authors.initials: M
authors.lastname: Pericin
authors.forename: E
authors.initials: E
authors.lastname: Kohler
authors.forename: J
authors.initials: J
authors.lastname: Barandun
authors.forename: G
authors.initials: G
authors.lastname: Burg
mesh_terms: D000328:Adult; D000368:Aged; D001941:Breast Diseases / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D014890:Granulomatosis with Polyangiitis / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged