Nonsteroidal anti-inflammatory drug induced duodenal web.
Duodenal webs represent an unusual cause of intestinal obstruction in adults. These anomalies are generally considered to be congenital in origin and usually present in infancy. However, they occasionally become symptomatic in adulthood. In these cases, because of the delay in symptoms, the etiology of duodenal webs in adults is uncertain. Gastrointestinal webs in adults have also been reported in the small intestine and colon. It is generally accepted that these lesions are an acquired defect related to long term nonsteroidal anti-inflammatory drug (NSAID) use. We report a patient with a history of long term NSAID use who presented with symptoms of gastric outlet obstruction due to the presence of a duodenal web.
Kannan
S
S
USD School of Medicine, Sioux Falls, USA.
McGreevy
P S
PS
Fullerton
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TE
D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D004380:Duodenal Obstruction / Q000139:chemically induced* / Q000175:diagnosis; D005260:Female; D017219:Gastric Outlet Obstruction / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D008134:Long-Term Care; D008881:Migraine Disorders / Q000188:drug therapy*; D009288:Naproxen / Q000008:administration & dosage / Q000009:adverse effects*
D000894:Anti-Inflammatory Agents, Non-Steroidal; D009288:Naproxen