Growth hormone treatment of short children born small for gestational age.
The administration of growth hormone (GH) for a short period to short children born small for gestational age increases growth velocity. Children receiving 2-3 times the replacement dose gained nearly 2.0 SDS in height over a 3-year treatment period. This treatment is well tolerated, without significant side-effects. Further studies of the growth rate following cessation of GH treatment will reveal whether the gain in height is maintained, and whether the final height prediction is improved.
Czernichow
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Pediatric Endocrinology and Diabetology Unit, Hospital Robert Debre, Paris, France.
D001827:Body Height / Q000187:drug effects*; D002675:Child, Preschool; D005317:Fetal Growth Retardation / Q000209:etiology; D019382:Human Growth Hormone / Q000627:therapeutic use*; D006801:Humans; D007236:Infant, Small for Gestational Age / Q000254:growth & development*
D019382:Human Growth Hormone