Endometrial carcinoma in a patient with blepharophimosis syndrome and menstrual abnormality.
OBJECTIVE
To describe a woman with blepharophimosis syndrome and menstrual abnormality who developed endometrial carcinoma.


METHODS
A 26-year-old woman with blepharophimosis syndrome and menstrual abnormality had increased serum luteinizing hormone and serum follicle-stimulating hormone levels. She was followed up for 5 years.


RESULTS
She developed endometrial carcinoma.


CONCLUSIONS
Patients with blepharophimosis syndrome and menstrual abnormality should be examined gynecologically. Hormone-dependent endometrial carcinoma may develop.
Matsuoka
Y
Y
Department of Ophthalmology, Shimane Medical University, Japan.
Shibuya
Y
Y
D000230:Adenocarcinoma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D000328:Adult; D000568:Amenorrhea / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D016569:Blepharophimosis / Q000150:complications* / Q000175:diagnosis / Q000235:genetics; D001763:Blepharoptosis / Q000150:complications / Q000151:congenital / Q000175:diagnosis; D016889:Endometrial Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D015785:Eye Diseases, Hereditary / Q000150:complications / Q000175:diagnosis / Q000235:genetics; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D005500:Follow-Up Studies; D006801:Humans; D007044:Hysterectomy; D007247:Infertility, Female / Q000097:blood / Q000150:complications / Q000175:diagnosis; D007986:Luteinizing Hormone / Q000097:blood; D010052:Ovariectomy; D010375:Pedigree; D012307:Risk Factors; D013577:Syndrome
D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone