title: The effects of methylmethacrylate's hyperthermic polymerization on cerebral vascular permeability.
abstract: This study was undertaken to analyze the effects of significant hyperthermia (> 100 degrees C) associated with the polymerization of polymethlymethacrylate (PMM) on the permeability of the cerebral vasculature in rats. The method used to visualize the pial vasculature included the open pial window technique and epifluorescence microscopy. Results indicated that there is a significant increase in cerebral vascular permeability following in situ polymerization of PMM over the craniectomy site.
authors.affiliation: Division of Neurosurgery, University of Missouri Health Sciences Center, Columbia, USA.
authors.forename: D F
authors.initials: DF
authors.lastname: Jimenez
authors.forename: C M
authors.initials: CM
authors.lastname: Barone
authors.forename: T
authors.initials: T
authors.lastname: Tigno
authors.forename: X F
authors.initials: XF
authors.lastname: Yang
authors.forename: A
authors.initials: A
authors.lastname: Clapper
mesh_terms: D000818:Animals; D001921:Brain / Q000098:blood supply*; D002199:Capillary Permeability / Q000502:physiology*; D005260:Female; D006358:Hot Temperature; D019904:Polymethyl Methacrylate / Q000138:chemical synthesis*; D051381:Rats; D017207:Rats, Sprague-Dawley
chemical_list: D019904:Polymethyl Methacrylate