[Computer-assisted microtelephotometric study of dysplasia and adenocarcinoma of the large intestine in patients with chronic nonspecific colitis].
Computer-aided microtelephotometry showed that the mean size of the nuclei gradually increases and their shape changes, and the total content of Feulgen DNA increases in patients with nonspecific ulcerative colitis in proportion to the severity of dysplasia and malignant degeneration of the mucosal epithelium of the large intestine. In first-degree dysplasia the value os 2.8, in second degree 5.0, in third degree 6.9; in cribriform structures of adenocarcinoma 8.6, in poorly differentiated cancer cells 10.9, and in highly polymorphous sites of adenocarcinoma as high as 20. Mathematical expression of different degree of dysplasia and of adenocarcinoma of the large intestine will no doubt facilitate the differential diagnosis of these processes and help universally assess them. A new technology of histocytological investigations - computer-aided microtelephotometry - permits the use of all types of telecommunications for consultations to be carried out all over the country.
Avtandilov
G G
GG
Chervonnaia
L V
LV
Simakina
E P
EP
D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology*; D001706:Biopsy; D003093:Colitis, Ulcerative / Q000175:diagnosis / Q000473:pathology*; D004273:DNA, Neoplasm / Q000032:analysis; D003937:Diagnosis, Differential; D006652:Histological Techniques; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007414:Intestinal Neoplasms / Q000175:diagnosis / Q000473:pathology*; D007420:Intestine, Large / Q000473:pathology; D010783:Photometry; D019113:Telepathology
D004273:DNA, Neoplasm