title: Isolated sphenoid sinus disease: an analysis of 132 cases.
abstract: Solitary involvement of the sphenoid sinus is a relatively uncommon entity. A series of 132 patients with isolated sphenoid disease accumulated over a 22-year period is reported. A retrospective chart review was performed with special attention to the patients' presenting signs, symptoms, and radiographic findings. There were 80 patients with inflammatory disease, 38 with neoplasms, four with fibroosseous disorders, and 10 with traumatic and developmental lesions. The most common presenting symptom was headache, followed by visual changes and cranial nerve palsies. Cranial nerve abnormalities were encountered in 12% of the inflammatory cases, 60% of the benign tumors, and 57% of the malignant tumors. Radiographically, bone remodeling was associated with chronic inflammatory disease, especially mucoceles. Bone erosion was found principally with neoplastic disease, occurring rarely with mucoceles. Extension was associated with malignant tumors.
authors.affiliation: Department of Otolaryngology-Head & Neck Surgery, The Mount Sinai Medical Center, New York, New York 10029, USA.
authors.forename: W
authors.initials: W
authors.lastname: Lawson
authors.forename: A J
authors.initials: AJ
authors.lastname: Reino
mesh_terms: D000293:Adolescent; D000368:Aged; D000465:Algorithms; D002547:Cerebral Palsy / Q000503:physiopathology; D002648:Child; D002908:Chronic Disease; D003391:Cranial Nerves / Q000503:physiopathology; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000150:complications; D006261:Headache / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012720:Severity of Illness Index; D012888:Skull Neoplasms / Q000150:complications / Q000473:pathology*; D015524:Sphenoid Sinusitis / Q000150:complications / Q000473:pathology* / Q000601:surgery; D014786:Vision Disorders / Q000209:etiology