Complete hydatidiform mole and coexisting normal fetuses. A report of two cases with contrasting outcomes.
BACKGROUND
Multiple pregnancies consisting of a complete hydatidiform mole and coexisting fetuses are relatively rare but may become more common due to the increasing use of ovulation-induction agents.


METHODS
We report on a twin and a triplet pregnancy, conceived using clomiphene citrate, with contrasting outcomes. The twin pregnancy resulted in a term delivery of a healthy singleton and the triplet pregnancy in a termination at 17 weeks followed by the development of choriocarcinoma.


CONCLUSIONS
The few cases available suggest that a subgroup of complete moles follows a more benign course and can be managed conservatively, allowing the pregnancy to go to term with appropriate follow-up, whereas other cases follow a more aggressive course. Larger case series are needed to develop definitive protocols.
Shahabi
S
S
Department of Obstetrics and Gynecology, Erasme Hospital, Free University of Brussels, Belgium.
Naome
G
G
Cobin
L
L
Verougstraete
A
A
Masters
L
L
Zengbe
V
V
Noël
J C
JC
Avni
E F
EF
Donner
C
C
Verhest
A
A
Foulon
W
W
Rodesch
F
F
D000328:Adult; D002822:Choriocarcinoma; D006063:Chorionic Gonadotropin / Q000097:blood; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000175:diagnosis / Q000503:physiopathology; D011247:Pregnancy; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple; D014594:Uterine Neoplasms
D006063:Chorionic Gonadotropin