title: Subcutaneous phaeohyphomycosis caused by Phoma cava. Report of a case and review of the literature.
abstract: We report a case of subcutaneous phaeohyphomycosis observed in a male patient presenting pulmonary sarcoidosis and submitted to corticosteroid treatment. He presented nodular erythematous-violaceous skin lesions in the dorsum of the right hand. Histopathological examination of the biopsied lesion revealed dematiaceous hyphae and yeast-like cells, with a granulomatous tissual reaction. The isolated fungus was identified as Phoma cava. A review of the literature on fungal infection caused by different Phoma species, is presented. The patient healed after therapy with amphotericin B. followed by itraconazole.
authors.affiliation: Faculty of Medical Sciences, Santa Casa de São Paulo, Brasil.
authors.forename: C
authors.initials: C
authors.lastname: Zaitz
authors.forename: E M
authors.initials: EM
authors.lastname: Heins-Vaccari
authors.forename: R S
authors.initials: RS
authors.lastname: de Freitas
authors.forename: G L
authors.initials: GL
authors.lastname: Arriagada
authors.forename: L
authors.initials: L
authors.lastname: Ruiz
authors.forename: S A
authors.initials: SA
authors.lastname: Totoli
authors.forename: A C
authors.initials: AC
authors.lastname: Marques
authors.forename: G G
authors.initials: GG
authors.lastname: Rezze
authors.forename: H
authors.initials: H
authors.lastname: Müller
authors.forename: N S
authors.initials: NS
authors.lastname: Valente
authors.forename: C da S
authors.initials: Cda S
authors.lastname: Lacaz
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D003904:Mitosporic Fungi / Q000302:isolation & purification; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole; D000666:Amphotericin B