title: [The effect of spasmolytics on dilatation of the uterine cervix].
abstract: Spasmolytics and spasmoanalgetic mixtures are administered to facilitate dilatation of the cervix during delivery and to shorten the first stage of labour. This medication is used in 70% deliveries at the 1st Dept. of Obstetrics and Gynaecology Masaryk University in Brno. The aim of the study was to analyze the spasmolytic effect on the process of cervix dilatation. The study comprises 108 uncomplicated deliveries (52 deliveries with spasmolytics and 56 deliveries without). We analyzed the effect of spasmolytics on the cervix, process of labour and outcome of delivery. Six kinds of spasmolytics were used, administered from once to four times during labour and most of them (85%) in the latent phase of the first stage of labour. In the group with spasmolytics there was statistically insignificant by prolonged active phase of the first stage of labour (126 vs 104 minutes) and more frequent administration of Oxytocin. Others parameters such as length of the second stage of labour, rate of birth injuries, the 1st minute Apgar score less than 7 and the necessity of neonatal resuscitation did not differ in the two groups.
  
  
  CONCLUSIONS
  The application of spasmolytics did not significantly affect the process of delivery.
authors.affiliation: I. gynek.-porod. klinika LF MU, Brno.
authors.forename: R
authors.initials: R
authors.lastname: Hudecek
authors.forename: J
authors.initials: J
authors.lastname: Nagy
authors.forename: V
authors.initials: V
authors.lastname: Unzeitig
mesh_terms: D000328:Adult; D002584:Cervix Uteri / Q000187:drug effects* / Q000502:physiology; D004106:Dilatation; D005260:Female; D006801:Humans; D007747:Labor Stage, First; D010276:Parasympatholytics / Q000008:administration & dosage*; D011247:Pregnancy
chemical_list: D010276:Parasympatholytics