Recovery of hearing and vocal behavior after hair-cell regeneration.
Postmitotic hair-cell regeneration in the inner ear of birds provides an opportunity to study the effect of renewed auditory input on auditory perception, vocal production, and vocal learning in a vertebrate. We used behavioral conditioning to test both perception and vocal production in a small Australian parrot, the budgerigar. Results show that both auditory perception and vocal production are disrupted when hair cells are damaged or lost but that these behaviors return to near normal over time. Precision in vocal production completely recovers well before recovery of full auditory function. These results may have particular relevance for understanding the relation between hearing loss and human speech production especially where there is consideration of an auditory prosthetic device. The present results show, at least for a bird, that even limited recovery of auditory input soon after deafening can support full recovery of vocal precision.
Dooling
R J
RJ
Department of Psychology, University of Maryland, College Park, MD 20742, USA. dooling@bss3.umd.edu
Ryals
B M
BM
Manabe
K
K
D000818:Animals; D001307:Auditory Perception / Q000502:physiology; D001309:Auditory Threshold / Q000502:physiology; D003213:Conditioning, Psychological / Q000502:physiology; D004192:Discrimination, Psychological / Q000502:physiology; D006198:Hair Cells, Auditory / Q000187:drug effects / Q000473:pathology / Q000502:physiology*; D006309:Hearing / Q000502:physiology*; D034381:Hearing Loss / Q000503:physiopathology / Q000523:psychology; D006801:Humans; D007612:Kanamycin / Q000633:toxicity; D007858:Learning / Q000502:physiology; D008297:Male; D010240:Parakeets / Q000502:physiology*; D012038:Regeneration / Q000502:physiology*; D013997:Time Factors; D014828:Vocalization, Animal / Q000502:physiology*
D007612:Kanamycin