title: Detection of noradrenaline-immunoreactive nerve fibres in rat liver by immunoelectron microscopy.
abstract: Noradrenergic innervation of rat liver was studied immunohistochemically using antibody to noradrenaline at the electron-microscopic level. Noradrenaline-immunoreactive nerve fibres were located in the portal tract and some were in close contact with the portal vein and hepatic artery. Noradrenaline-immunoreactive fibres were found to contain many vesicles that were reactive to anti-noradrenaline antibody. This preliminary study suggests that the method for detecting noradrenaline-immunoreactive fibres using the antibody is useful for studies at the electron-microscopic level.
authors.affiliation: Second Department of Internal Medicine, Nagoya University School of Medicine, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Fukuda
authors.forename: M
authors.initials: M
authors.lastname: Imoto
authors.forename: I
authors.initials: I
authors.lastname: Nakano
authors.forename: Y
authors.initials: Y
authors.lastname: Katano
authors.forename: T
authors.initials: T
authors.lastname: Hayakawa
mesh_terms: D000818:Animals; D006499:Hepatic Artery; D008099:Liver / Q000098:blood supply / Q000294:innervation*; D008297:Male; D016253:Microscopy, Immunoelectron / Q000379:methods; D009412:Nerve Fibers / Q000648:ultrastructure*; D009638:Norepinephrine / Q000032:analysis*; D011169:Portal Vein; D051381:Rats; D017208:Rats, Wistar
chemical_list: D009638:Norepinephrine