title: Fatal rhabdomyolysis in a flame burn patient.
abstract: Rhabdomyolysis due to flame burns is not well described. A case of fatal rhabdomyolysis in an epileptic patient who sustained 65 per cent body surface area, very deep, flame burns is described. It appears as if the sustained muscle compression from the restrictive, circumferential eschar was the major factor in the aetiology of the rhabdomyolysis. Despite aggressive fluid management, the patient died of acute renal failure and adult respiratory distress syndrome. We have subsequently identified three other cases of pigmenturia occurring following burns. It would seem as if rhabdomyolysis following extensive full thickness burns may be more common than previously suggested. Fluid requirements are in excess of those proposed by traditional protocols. Rhabdomyolysis in flame burn patients indicates a poor prognosis.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Groote Schuur Hospital, Observatory, Cape Town, South Africa.
authors.forename: D
authors.initials: D
authors.lastname: Lazarus
authors.forename: D A
authors.initials: DA
authors.lastname: Hudson
mesh_terms: D000061:Accidents, Home; D000328:Adult; D002056:Burns / Q000150:complications* / Q000473:pathology / Q000628:therapy; D004827:Epilepsy / Q000150:complications; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012206:Rhabdomyolysis / Q000209:etiology* / Q000473:pathology