Pro-inflammatory signaling: last pieces in the NF-kappaB puzzle?
The discovery of three previously unknown kinases that are essential for signaling in response to tumour necrosis factor and interleukin-1 has provided the missing link in the pathway that activates inflammatory genes.
Baeuerle
P A
PA
Tularik Inc., Two Corporate Drive, South San Francisco, California 94080, USA. baeuerle@tularik.com
D000818:Animals; D006801:Humans; D007249:Inflammation / Q000209:etiology*; D016328:NF-kappa B / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*
D016328:NF-kappa B