title: Safety of hospitalized ventilator-dependent children outside of the intensive care unit.
abstract: OBJECTIVE
  Hospitalization of clinically stable ventilator-dependent children in an intensive care unit (ICU) remains the standard in most pediatric centers. The aim of this study was to determine whether chronically ventilator-dependent children could be hospitalized safely in a non-ICU setting.
  
  
  METHODS
  All ventilator-dependent children who were hospitalized on the pediatric wards at Childrens Hospital Los Angeles from December 1992 through June 1996 were reviewed retrospectively (N = 63) and compared with the general pediatric ward population hospitalized during the same period. Data collected included the number of unexpected ICU transfers from the pediatric ward and the number of deaths that occurred on the ward.
  
  
  RESULTS
  The ventilator-dependent children on the pediatric wards had 11 emergency readmissions to the ICU for unexpected deterioration. This represented an unexpected ICU transfer rate of 2.7 per 1000 patient-days on the wards. The general pediatric ward population had an unexpected ICU transfer rate of 3.3 per 1000 patient-days, which was not significantly different from that of ventilator-dependent children on the wards. There were three ward deaths among the ventilator-dependent children, but all of these patients had advance directive status (do not resuscitate). This represented a rate of seven deaths per 10,000 patient-days on the wards, which was not significantly different from those of nonventilator-dependent ward patients (eight deaths per 10,000 patient-days).
  
  
  CONCLUSIONS
  We conclude that ventilator-dependent children hospitalized outside of the ICU do not have an increased incidence of deaths and unexpected ICU admissions compared with nonventilator-dependent inpatients. We speculate that hospital care of stable ventilator-dependent children can be provided safely outside of an ICU and at lower cost.
authors.affiliation: Division of Pediatric Pulmonology, Childrens Hospital Los Angeles, University of Southern California School of Medicine 90027, USA.
authors.forename: I U
authors.initials: IU
authors.lastname: Ambrosio
authors.forename: M S
authors.initials: MS
authors.lastname: Woo
authors.forename: M T
authors.initials: MT
authors.lastname: Jansen
authors.forename: T G
authors.initials: TG
authors.lastname: Keens
mesh_terms: D002648:Child; D006748:Hospital Departments; D017052:Hospital Mortality; D006760:Hospitalization; D006776:Hospitals, Pediatric / Q000458:organization & administration; D006801:Humans; D015278:Intensive Care Units, Pediatric; D015141:Los Angeles; D010360:Patient Transfer; D012121:Respiration, Artificial; D012189:Retrospective Studies