title: Systemic absorption of gentamicin ear drops.
abstract: Aminoglycoside-containing topical preparations are commonly used in the treatment of chronic suppurative otitis media and otitis externa. We report a case where systemic absorption of topical Gentisone HC occurred producing a serum gentamicin level of 6.2 micrograms/ml.
authors.affiliation: Department of Otolaryngology, Royal Preston Hospital, UK.
authors.forename: K M
authors.initials: KM
authors.lastname: Green
authors.forename: D W
authors.initials: DW
authors.lastname: Lappin
authors.forename: J W
authors.initials: JW
authors.lastname: Curley
authors.forename: J P
authors.initials: JP
authors.lastname: de Carpentier
mesh_terms: D000042:Absorption; D000287:Administration, Topical; D000900:Anti-Bacterial Agents / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use; D005839:Gentamicins / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood; D008297:Male; D008875:Middle Aged; D010035:Otitis Media, Suppurative / Q000097:blood* / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D005839:Gentamicins