title: Evaluation and prognostic significance of left ventricular diastolic function assessed by Doppler echocardiography in the early phase of a first acute myocardial infarction.
abstract: OBJECTIVE
  To study the prognostic significance of left ventricular diastolic function evaluated by transmitral and pulmonary venous flow velocities obtained in the early phase of a first acute myocardial infarction in relation to later development of congestive heart failure.
  
  
  METHODS
  Pulsed Doppler echocardiography of transmitral and pulmonary venous flow was assessed in 65 consecutive patients with a first myocardial infarction within 1 h of arrival in the coronary care unit.
  
  
  RESULTS
  A univariate regression analysis identified age, left ventricular ejection fraction < or = 45%, mitral E deceleration time < or = 130 ms, E/A ratio > 1.5, peak pulmonary venous atrial flow velocity > or = 30 cm.s-1 and a difference between mitral and pulmonary venous atrial flow duration < 0 ms as variables significantly related to the development of congestive heart failure. However, in a multivariate analysis only mitral E deceleration time < or = 130 ms and age were significant independent variables related to the development of congestive heart failure during the first week following a first acute myocardial infarction.
  
  
  CONCLUSIONS
  Assessment of left ventricular diastolic function complements measurements of systolic function in the evaluation of cardiac function, and mitral deceleration < or = 130 ms best identifies patients at risk of development of congestive heart failure following acute myocardial infarction.
authors.affiliation: Department of Medicine, Haderslev Hospital, Denmark.
authors.forename: S H
authors.initials: SH
authors.lastname: Poulsen
authors.forename: S E
authors.initials: SE
authors.lastname: Jensen
authors.forename: O
authors.initials: O
authors.lastname: Gøtzsche
authors.forename: K
authors.initials: K
authors.lastname: Egstrup
mesh_terms: D000368:Aged; D003971:Diastole; D015150:Echocardiography, Doppler; D005260:Female; D006333:Heart Failure / Q000209:etiology; D006439:Hemodynamics; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000503:physiopathology*; D011379:Prognosis; D011446:Prospective Studies; D016277:Ventricular Function, Left