Odor identification in Huntington's disease patients and asymptomatic gene carriers.
Odor identification was assessed in 20 Huntington's disease (HD) patients, 20 normal adults with the genetic mutation that causes HD, and 20 mutation-negative adults. The University of Pennsylvania Smell Identification Test (UPSIT) revealed substantial odor identification deficits only in HD patients.
Bylsma
F W
FW
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287-7218, USA. fbylsma@welchlink.welch.jhu.edu
Moberg
P J
PJ
Doty
R L
RL
Brandt
J
J
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D015870:Gene Expression; D006579:Heterozygote; D006801:Humans; D006816:Huntington Disease / Q000235:genetics* / Q000523:psychology*; D008297:Male; D008875:Middle Aged; D009154:Mutation; D011569:Psychiatric Status Rating Scales; D012903:Smell / Q000502:physiology*