title: Vertebral body infarction as a confirmatory sign of spinal cord ischemic stroke: report of three cases and review of the literature.
abstract: BACKGROUND
  Acute spontaneous spinal cord syndromes often remain etiologically ambiguous despite extensive diagnostic efforts. In the previous literature five cases are described with acute spinal cord syndromes interpreted as spinal cord ischemic strokes because of association with vertebral body infarctions on MRI.
  
  
  METHODS
  Three cases are presented, and the literature is reviewed. In addition to an extensive diagnostic battery including an initial MRI without pathological signs, follow-up MRI at different time intervals from the onset of symptoms showed T2 hyperintense signals in vertebral bodies. Patient 1, who had plaques in the abdominal aorta, had suffered a thoracolumbar spinal infarction; this and a concomitant infarction of the left portion of T-12 could be demonstrated on follow-up MRI on day 12. Patient 2, who had incomplete transverse spinal artery syndrome below T-3, had an abnormal signal at the T-2 level of the spinal cord on follow-up MRI on day 5; this was one segment above infarction of the dorsal area of T-3, corresponding to the ascending course of the medullary artery. The spinal cord of patient 3, who had a posterior spinal artery syndrome below T-11, was unremarkable on follow-up MRI on day 14, but a T2 hyperintense signal was noted in the dorsal area of T-10.
  
  
  CONCLUSIONS
  Vertebral body infarction represents the only confirmatory sign for the otherwise exclusionary diagnostic procedure for spinal cord ischemic stroke and must be searched for on follow-up MRI as a key to correct diagnosis.
authors.affiliation: Department of Neurology, Klinikum Minden, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Faig
authors.forename: O
authors.initials: O
authors.lastname: Busse
authors.forename: R
authors.initials: R
authors.lastname: Salbeck
mesh_terms: D000368:Aged; D001012:Aorta, Abdominal / Q000473:pathology; D001018:Aortic Diseases / Q000175:diagnosis; D001158:Arteries / Q000473:pathology; D001161:Arteriosclerosis / Q000175:diagnosis; D002561:Cerebrovascular Disorders / Q000150:complications / Q000175:diagnosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007238:Infarction / Q000175:diagnosis / Q000209:etiology*; D007511:Ischemia / Q000150:complications* / Q000175:diagnosis; D008159:Lumbar Vertebrae / Q000098:blood supply; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D013116:Spinal Cord / Q000098:blood supply*; D013131:Spine / Q000098:blood supply*; D013577:Syndrome; D013904:Thoracic Vertebrae / Q000098:blood supply