title: [Therapy of hyperuricemia and gout].
abstract: Therapy of hyperuricemia and gout has to depend on pathogenesis and stage of the disease. Dietary regimen are in the forefront in treatment of asymptomatic hyperuricemia. Uric acid lowering drugs can only be supported in repeated serum-measures from 9 mg/dl up. The therapy of an acute attack of gout primarily is done with non-steroidal antiinflammatory drugs, in rare cases with colchicine or corticoids. Gouty arthritis in intermission, independent of the extent of hyperuricemia, as well as chronic gout are indications for an uric acid lowering pharmacotherapy, usually for life. A special therapeutic challenge arises out of renal complications and the frequent association with the metabolic syndrome.
authors.affiliation: Sonderkrankenanstalt für rheumatische Erkrankungen und Herzkreislaufkrankheiten der Pensionsversicherungsanstalt für Arbeiter, Saalfelden.
authors.forename: G
authors.initials: G
authors.lastname: Pöllmann
authors.forename: W
authors.initials: W
authors.lastname: Kullich
authors.forename: G
authors.initials: G
authors.lastname: Klein
mesh_terms: D000208:Acute Disease; D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D015210:Arthritis, Gouty / Q000145:classification / Q000188:drug therapy* / Q000209:etiology; D003078:Colchicine / Q000627:therapeutic use; D006073:Gout / Q000145:classification / Q000188:drug therapy* / Q000209:etiology; D006074:Gout Suppressants / Q000627:therapeutic use*; D006801:Humans; D014527:Uric Acid / Q000097:blood*
chemical_list: D000305:Adrenal Cortex Hormones; D000894:Anti-Inflammatory Agents, Non-Steroidal; D006074:Gout Suppressants; D014527:Uric Acid; D003078:Colchicine