Vancomycin-resistant enterococci. Mechanism and clinical relevance.
Vancomycin-resistant enterococci have spread widely throughout the United States. Mechanisms of glycopeptide resistance are understood to a significant extent. These organisms are associated with considerable morbidity. Treatment options are limited, and control of their spread requires considerable effort and results in increased costs.
Eliopoulos
G M
GM
Harvard Medical School, Boston, Massachusetts, USA.
D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology; D004352:Drug Resistance, Microbial / Q000235:genetics; D016983:Enterococcus / Q000187:drug effects* / Q000235:genetics; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D012307:Risk Factors; D014640:Vancomycin / Q000494:pharmacology* / Q000627:therapeutic use*
D000900:Anti-Bacterial Agents; D014640:Vancomycin