Microbial immunology: a new mechanism for immune subversion.
The number of mechanisms that have evolved in microbes to subvert the immune response seems limitless. Tubercle bacilli have found a novel way to coat themselves with the C3 complement protein and invade macrophages by interactions with complement receptors.
Lachmann
P J
PJ
Microbial Immunology Group, University of Cambridge, Centre for Veterinary Science, Madingley Road, Cambridge, CB3 OES, UK.
D001426:Bacterial Proteins / Q000276:immunology* / Q000378:metabolism; D003175:Complement C2 / Q000172:deficiency / Q000276:immunology; D050678:Complement C2a; D003176:Complement C3 / Q000276:immunology*; D050577:Complement C3-C5 Convertases / Q000378:metabolism; D015935:Complement C4b / Q000276:immunology*; D003171:Complement Pathway, Classical; D003165:Complement System Proteins / Q000502:physiology*; D006801:Humans; D008264:Macrophages / Q000382:microbiology*; D018716:Molecular Mimicry; D009169:Mycobacterium tuberculosis / Q000276:immunology*; D044465:White People / Q000235:genetics
D001426:Bacterial Proteins; D003175:Complement C2; D003176:Complement C3; D015935:Complement C4b; D003165:Complement System Proteins; D050577:Complement C3-C5 Convertases; D050678:Complement C2a