High-intensity lesion on T1-weighted MR images in neurofibromatosis type 1: a case of premalignant lesion.
We report a patient with NF1, who was followed up because of an optic glioma and one enhancing lesion presumed to be a pilocytic astrocytoma. T1- and T2-weighted MR images showed also a hyperintense periventricular lesion with no enhancement and no mass effect, of an unsuspected nature. Three years later a glioblastoma multiforme developed at the site of this preceding lesion.
Miaux
Y
Y
Department of Neuroradiology Charcot, Salpêtrière Hospital, Paris, France.
Guermazi
A
A
Cornu
P
P
Mokhtari
K
K
Singer
B
B
Chiras
J
J
Blanchet-Bardon
C
C
D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis*; D005260:Female; D005909:Glioblastoma / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D009456:Neurofibromatosis 1 / Q000175:diagnosis*; D011230:Precancerous Conditions / Q000175:diagnosis*