[The apolipoprotein AII gene is not a risk factor for development ischemic heart disease in the Moscow population].
Polymorphism of microsatellite (CA)n repeat in the second intron of the apolipoprotein AH gene--one of the major structural proteins of high-density lipoproteins--was performed in male coronary heart disease (CHD) patients and in a random sample of men from the Moscow population. No association between the polymorphism and the development of CHD was revealed. Therefore, apolipoprotein AII gene is not a factor of genetic risk of the development of atherosclerosis in the population studied.
Shadrina
M I
MI
Slominskiĭ
P A
PA
Perova
N V
NV
Limborskaia
S A
SA
D000328:Adult; D000483:Alleles; D016633:Apolipoprotein A-II / Q000235:genetics*; D006801:Humans; D008077:Lipoproteins, LDL / Q000235:genetics; D008297:Male; D018895:Microsatellite Repeats; D008875:Middle Aged; D009031:Moscow; D017202:Myocardial Ischemia / Q000235:genetics*; D011110:Polymorphism, Genetic; D012307:Risk Factors
D016633:Apolipoprotein A-II; D008077:Lipoproteins, LDL