title: [Effect of medicamentous cholesterol control on resources utilization in public health--significance of the Scandinavian Simvastatin Survival Study (4-S Study) for cost control in Swiss health management conditions].
abstract: Upward spiralling health care expenditures have triggered the need to assess the cost-effectiveness of medical interventions. Specifically, interventions in primary and secondary prevention represent an important field of research. A resource utilization analysis was performed on the basis of the recently published Scandinavian Simvastatin Survival Study. It could be shown that treatment with simvastatin compared to placebo leads to a reduction in patient costs of CHF 8.4 million. This represents a reduction of CHF 3770.- per patient. The effective daily treatment costs can thus be calculated at CHF 1.11, which is equivalent to 36% of the actual acquisition cost per day. These results support the notion that secondary coronary prevention is not only justified from a clinical but also from an economic point of view.
authors.affiliation: Zentrum für Pharmakoökonomie, Universität Mailand.
authors.forename: T D
authors.initials: TD
authors.lastname: Szucs
authors.forename: T F
authors.initials: TF
authors.lastname: Lüscher
authors.forename: F
authors.initials: F
authors.lastname: Gutzwiller
mesh_terms: D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000188:drug therapy / Q000191:economics / Q000401:mortality; D000924:Anticholesteremic Agents / Q000009:adverse effects / Q000191:economics / Q000627:therapeutic use*; D003363:Cost Control / Q000639:trends; D003362:Cost-Benefit Analysis; D005260:Female; D005544:Forecasting; D017048:Health Care Costs / Q000706:statistics & numerical data*; D006300:Health Services Misuse / Q000191:economics*; D006801:Humans; D006937:Hypercholesterolemia / Q000188:drug therapy* / Q000191:economics / Q000401:mortality; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000188:drug therapy / Q000191:economics / Q000401:mortality; D012537:Scandinavian and Nordic Countries / Q000453:epidemiology; D019821:Simvastatin / Q000009:adverse effects / Q000191:economics / Q000627:therapeutic use*; D015996:Survival Rate; D013557:Switzerland / Q000453:epidemiology
chemical_list: D000924:Anticholesteremic Agents; D019821:Simvastatin