title: MRI of the hypopharynx with provocative maneuvers.
abstract: The purpose of this study was to assess the validity of magnetic resonance (MR) functional images of the hypopharynx. Following T2-weighted spin-echo sequences during quiet respiration, contrast enhanced 2D-Turbo-FLASH sequences were obtained during Valsalva-maneuver, quiet respiration, A- and U-phonation, respectively. Tumor detection was clearly improved using functional MRI (sensitivity of 97.4%, specificity 83.3%, accuracy 95.5%) when compared with MRI during quiet respiration (sensitivity of 87.1%, specificity 33.3%, accuracy 80%). Rapid MR sequences such as 2D-Turbo FLASH allow functional imaging of the hypopharynx, thereby improving MR diagnosis of hypopharyngeal tumors.
authors.affiliation: Department of Radiology, University of Regensburg, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Held
authors.forename: C
authors.initials: C
authors.lastname: Fellner
authors.forename: J
authors.initials: J
authors.lastname: Seitz
authors.forename: A
authors.initials: A
authors.lastname: Geissler
authors.forename: V
authors.initials: V
authors.lastname: Bonkowsky
mesh_terms: D000328:Adult; D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis* / Q000628:therapy; D003287:Contrast Media; D005260:Female; D005500:Follow-Up Studies; D019786:Gadolinium DTPA; D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000175:diagnosis* / Q000628:therapy; D007013:Hypopharynx / Q000473:pathology*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis; D009367:Neoplasm Staging; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014636:Valsalva Maneuver
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA