Chronic active mononucleosis.
A 16-year-old girl with 3 clinical episodes of mononucleosis during a period of more than 2 year is presented. The patient had persistently elevated VCA-IgM antibodies during follow-up for 15 months until she became EBNA-positive. This is a case of prolonged primary EBV infection and late seroconversion as clinical restitution and development of EBNA antibodies occurred 2 year after the onset of clinical illness.
Kragsbjerg
P
P
Department of Internal Medicine, Sonderborg Hospital, Denmark.
D000293:Adolescent; D000914:Antibodies, Viral / Q000096:biosynthesis*; D002908:Chronic Disease; D005260:Female; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D007244:Infectious Mononucleosis / Q000276:immunology* / Q000503:physiopathology
D000914:Antibodies, Viral