title: [Determination of the potential doubling time of tumors using bromodeoxyuridine and flow cytometry].
abstract: Tumor growth-rate affects prognosis and treatment planning. The injection of bromodeoxyuridine in dogs and cats permits determination of the potential doubling time following a biopsy of neoplastic tissue and flow cytometric analysis. The essentially non-invasive method gives exact results within 24 hours. This report describes a method to measure potential tumor doubling time of different tumors, and presents results of canine and feline tumors.
authors.affiliation: Veterinär-medizinisches Departement, Universität Zürich.
authors.forename: U
authors.initials: U
authors.lastname: Schwyn
authors.forename: B
authors.initials: B
authors.lastname: Kaser-Hotz
authors.forename: B
authors.initials: B
authors.lastname: Hauser
authors.forename: G
authors.initials: G
authors.lastname: Fodor
authors.forename: H
authors.initials: H
authors.lastname: Ruckstuhl
authors.forename: N E
authors.initials: NE
authors.lastname: Crompton
mesh_terms: D000818:Animals; D000964:Antimetabolites, Antineoplastic; D001706:Biopsy / Q000662:veterinary; D001973:Bromodeoxyuridine; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005434:Flow Cytometry / Q000662:veterinary; D009369:Neoplasms / Q000473:pathology / Q000662:veterinary*; D011379:Prognosis; D013997:Time Factors
chemical_list: D000964:Antimetabolites, Antineoplastic; D001973:Bromodeoxyuridine