title: Interleukin 18, a cytokine which resembles IL-1 structurally and IL-12 functionally but exerts its effect independently of both.
authors.affiliation: Fujisaki Institute, Hayashibara Biochemical Laboratories, Inc., Okayama, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kohno
authors.forename: M
authors.initials: M
authors.lastname: Kurimoto
mesh_terms: D000311:Adrenal Glands / Q000378:metabolism; D000818:Animals; D019556:COS Cells; D003110:Colonic Neoplasms / Q000628:therapy; D016207:Cytokines / Q000737:chemistry / Q000494:pharmacology / Q000502:physiology* / Q000627:therapeutic use; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D007371:Interferon-gamma / Q000096:biosynthesis; D020382:Interleukin-18; D053727:Interleukin-18 Receptor alpha Subunit; D007694:Killer Cells, Natural / Q000187:drug effects; D007728:Kupffer Cells / Q000378:metabolism; D051379:Mice; D008807:Mice, Inbred BALB C; D018123:Receptors, Interleukin / Q000502:physiology; D053724:Receptors, Interleukin-18; D011993:Recombinant Fusion Proteins / Q000378:metabolism; D015398:Signal Transduction; D013601:T-Lymphocytes / Q000187:drug effects; D014162:Transfection; D014407:Tumor Cells, Cultured
chemical_list: D016207:Cytokines; C508572:IL18R1 protein, human; C508573:Il18r1 protein, mouse; D007155:Immunologic Factors; D020382:Interleukin-18; D053727:Interleukin-18 Receptor alpha Subunit; D018123:Receptors, Interleukin; D053724:Receptors, Interleukin-18; D011993:Recombinant Fusion Proteins; D007371:Interferon-gamma