Reticuloendothelial "activation" noted after splenectomy for ITP and presence of a post-poliomyelitis asymmetry.
A radiocolloid study was carried out, after splenectomy, in a 75-year-old man who had idiopathic thrombocytopenic purpura. The patient, who did not have an increase in platelet counts after spleen removal or after platelet infusions, showed radiocolloid accumulation in the lungs and in the bone marrow. This suggested some "activation" of reticuloendothelial cells, perhaps by circulating immune complexes. The left femur (site of an episode of poliomyelitis many years previously) had less radiocolloid uptake than the right.
Spencer
R P
RP
Department of Nuclear Medicine, University of Connecticut Health Center, Farmington 06030, USA.
Mittal
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P
D000368:Aged; D000936:Antigen-Antibody Complex / Q000097:blood; D001853:Bone Marrow / Q000000981:diagnostic imaging / Q000502:physiology; D005269:Femur / Q000000981:diagnostic imaging; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000502:physiology; D008168:Lung / Q000000981:diagnostic imaging / Q000502:physiology; D008297:Male; D012157:Mononuclear Phagocyte System / Q000000981:diagnostic imaging* / Q000502:physiology; D010976:Platelet Count; D017713:Platelet Transfusion; D016262:Postpoliomyelitis Syndrome / Q000000981:diagnostic imaging*; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000000981:diagnostic imaging / Q000276:immunology / Q000601:surgery*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013156:Splenectomy; D013671:Technetium Tc 99m Sulfur Colloid
D000936:Antigen-Antibody Complex; D019275:Radiopharmaceuticals; D013671:Technetium Tc 99m Sulfur Colloid