title: [Inhaled nitric oxide after Fontan type operation].
abstract: The indication of Fontan type operation has been extending, but some cases on the boundary of the indication resulted in low cardiac output syndrome (LOS) postoperatively. Recently the inhalation of nitric oxide (NO) has been revealed to produce selective pulmonary vasodilatation, and it has come to be applied in the clinical setting. We experienced a case of 6-year-old boy with complex cardiac anomaly in whom the inhalation of nitric oxide was remarkably effective for the LOS caused by increased pulmonary vascular resistance after Fontan type operation. In the case various conventional treatments failed to improve his LOS during the weaning from a respirator on the second postoperative day. After the initiation of the inhalation of nitric oxide at a concentration of 6ppm, a rapid decreasing of pulmonary artery pressure concomitant with an improvement of hemodynamics were obtained. We concluded that the inhalation of nitric oxide is an effective strategy for the increased pulmonary resistance after Fontan type operation.
authors.affiliation: National Cardiovascular Center, Department of Cardiovascular Surgery, Osaka.
authors.forename: T
authors.initials: T
authors.lastname: Ishizaka
authors.forename: K
authors.initials: K
authors.lastname: Kumon
authors.forename: N
authors.initials: N
authors.lastname: Yahagi
authors.forename: H
authors.initials: H
authors.lastname: Tanigami
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
authors.forename: O
authors.initials: O
authors.lastname: Matsuki
authors.forename: M
authors.initials: M
authors.lastname: Nakaya
authors.forename: M
authors.initials: M
authors.lastname: Nishigaki
authors.forename: F
authors.initials: F
authors.lastname: Yamamoto
authors.forename: T
authors.initials: T
authors.lastname: Yagihara
mesh_terms: D000280:Administration, Inhalation; D018685:Anesthetics, Inhalation / Q000008:administration & dosage*; D002303:Cardiac Output, Low / Q000188:drug therapy; D002648:Child; D018729:Fontan Procedure; D006330:Heart Defects, Congenital / Q000601:surgery; D006801:Humans; D008297:Male; D009609:Nitrous Oxide / Q000008:administration & dosage*; D011183:Postoperative Complications / Q000188:drug therapy; D014655:Vascular Resistance / Q000187:drug effects; D014665:Vasodilator Agents / Q000008:administration & dosage*
chemical_list: D018685:Anesthetics, Inhalation; D014665:Vasodilator Agents; D009609:Nitrous Oxide