title: The effect of the OmpT protease on excision repair in UV-irradiated Escherichia coli.
abstract: The extent of pyrimidine dimer excision (PDE) was inhibited in UV-irradiated E. coli KS272 (ompT+) cells when they were preinduced by a low UV predose preceded by a nutrition stress but not in the preinduced E.coli SF100 (ompT-) mutants. The preinduction, however, markedly inhibited PDE in the ompT- cells transformed with a multicopy plasmid carrying ompT gene. The data are consistent with the hypothesis that the inducible OmpT protease (controlled by rpoH) might terminate the SOS period of excision repair so that when cells are preinduced PDE might be inhibited prematurely.
authors.affiliation: Department of Molecular Genetics, Slovak Academy of Sciences, Bratislava, Slovak Republic.
authors.forename: M
authors.initials: M
authors.lastname: Sedliaková
authors.forename: F
authors.initials: F
authors.lastname: Masek
authors.forename: V
authors.initials: V
authors.lastname: Slezáriková
authors.forename: M
authors.initials: M
authors.lastname: Pirsel
mesh_terms: D004249:DNA Damage; D004260:DNA Repair; D004269:DNA, Bacterial / Q000528:radiation effects; D004926:Escherichia coli / Q000235:genetics* / Q000528:radiation effects; D017353:Gene Deletion; D012697:Serine Endopeptidases / Q000235:genetics / Q000378:metabolism*; D014466:Ultraviolet Rays
chemical_list: D004269:DNA, Bacterial; D012697:Serine Endopeptidases; C057840:omptin outer membrane protease