Innovative approaches to novel antibacterial drug discovery.
Increasing antibiotic resistance in microorganisms and new emerging pathogens have become a major problem in our society. Rising to satisfy this urgent medical need is a recent confluence of powerful new drug discovery technologies: combinatorial chemistry; sequence and functional genomic analysis; and novel methods of high-throughput screening. The combination of these technologies will bring to bear untapped power in the search for new antimicrobials.
Trias
J
J
Versicor, Fremont, CA 94555, USA.
Gordon
E M
EM
D000890:Anti-Infective Agents; D015195:Drug Design; D004352:Drug Resistance, Microbial / Q000235:genetics; D005798:Genes, Bacterial; D008826:Microbial Sensitivity Tests
D000890:Anti-Infective Agents