title: [The search for new antiparasitic agents. 18. The synthesis and antitrichinelliasis activity of 1-[(2-acylamino)phenyl]-3,4-dihydroisoquinolines].
abstract: New 1-[(2-acylamino)phenyl]-3, 4-dihydroisoquinolines were synthesized and tested for their acute toxicity and antitrichinosis activity. The above compounds were found to show their low toxicity and two compounds (G-1615 and G-1616) displayed a high antitrichinosis effect.
authors.forename: F S
authors.initials: FS
authors.lastname: Mikhaĭlitsyn
authors.forename: N P
authors.initials: NP
authors.lastname: Kozyreva
authors.forename: N L
authors.initials: NL
authors.lastname: Veretennikova
authors.forename: B A
authors.initials: BA
authors.lastname: Astaf'ev
authors.forename: M N
authors.initials: MN
authors.lastname: Lebedeva
authors.forename: N D
authors.initials: ND
authors.lastname: Lychko
mesh_terms: D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000969:Antinematodal Agents / Q000737:chemistry* / Q000627:therapeutic use* / Q000633:toxicity; D004353:Drug Evaluation, Preclinical; D007546:Isoquinolines / Q000737:chemistry* / Q000627:therapeutic use* / Q000633:toxicity; D051379:Mice; D017160:Trichinella spiralis; D014235:Trichinellosis / Q000188:drug therapy*
chemical_list: D000969:Antinematodal Agents; C109852:G 1616; C109853:G 1617; D007546:Isoquinolines; D015766:Albendazole