Netherton syndrome presenting as congenital psoriasis.
A white boy had erythroderma and dense scale at birth. By 3 months the scale had localized to scalp, diaper area, and acral surfaces. Two biopsy specimens were read as psoriasiform dermatitis at 1 and 3 months. It was not until he was 10 months of age, when terminal hairs grew with nodose irregularities (trichorrhexis invaginatum), that the correct diagnosis of Netherton syndrome was made.
Shwayder
T
T
Henry Ford Hospital, Wayne State University School of Medicine, Detroit, Michigan, USA.
Banerjee
S
S
D001706:Biopsy; D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006197:Hair / Q000002:abnormalities* / Q000648:ultrastructure; D006201:Hair Diseases / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D016113:Ichthyosiform Erythroderma, Congenital / Q000175:diagnosis* / Q000473:pathology; D007223:Infant; D008297:Male; D011565:Psoriasis / Q000151:congenital / Q000175:diagnosis*; D012867:Skin / Q000473:pathology; D013577:Syndrome