Adenocarcinoma of the gastric cardia.
Although adenocarcinoma of the stomach has decreased in incidence over the past several decades, cancer of the gastric cardia has increased rapidly over this time frame. There are several differences between adenocarcinoma of the cardia and distal stomach with respect to epidemiology, risk factors, and prognosis. In addition, recent data raise questions with regard to possible associations of cardia cancer with Barrett's esophagus, intestinal metaplasia of the cardia, and Helicobacter pylori. This article will review the current literature with regard to this important tumor and explore these potential disease associations.
Morales
T G
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Gastroenterology Section, University of Arizona Health Sciences Center, Tucson 85724, USA.
D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology; D001471:Barrett Esophagus / Q000150:complications / Q000473:pathology; D002299:Cardia; D016481:Helicobacter Infections / Q000150:complications; D016480:Helicobacter pylori; D006801:Humans; D009367:Neoplasm Staging; D011379:Prognosis; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000150:complications / Q000473:pathology