Treatment of superficial ulcerative squamous cell carcinoma in three horses with topical 5-fluorouracil.
Three horses with superficial ulcerative squamous cell carcinoma were successfully treated with topical 5-fluorouracil. Two of them remain in remission after a single course of treatment and the third case is controlled by the application of the cream for seven days every six weeks. No systemic side-effects were observed but there was a localised inflammatory reaction in the skin in each case.
Paterson
S
S
Animal Medical Centre, Chorlton.
D000287:Administration, Topical; D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000627:therapeutic use*; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage / Q000627:therapeutic use*; D006734:Horse Diseases / Q000188:drug therapy* / Q000473:pathology; D006736:Horses; D008297:Male; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*
D000964:Antimetabolites, Antineoplastic; D005472:Fluorouracil