A case of nondigitalis cardiac glycoside toxicity.
A case is presented of cardiac glycoside poisoning in a 1-year-old patient from the plant Nerium oleander (common oleander). The patient had bradycardia, vomiting, altered level of consciousness, and no history of ingestion. Antibody-based digoxin assays may cross-react with other cardiac glycosides nonquantitatively. Chromatographic techniques can be used in the specific diagnosis.
Gupta
A
A
Department of Paediatrics, Hospital for Sick Children, University of Toronto, Ontario, Canada.
Joshi
P
P
Jortani
S A
SA
Valdes
R
R
Thorkelsson
T
T
Verjee
Z
Z
Shemie
S
S
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000276:immunology; D001919:Bradycardia / Q000209:etiology*; D002298:Cardenolides / Q000302:isolation & purification; D002851:Chromatography, High Pressure Liquid; D003429:Cross Reactions; D004077:Digoxin / Q000276:immunology; D005189:False Positive Reactions; D006027:Glycosides / Q000506:poisoning*; D006801:Humans; D007118:Immunoassay / Q000379:methods; D007223:Infant; D008297:Male; D010939:Plant Poisoning / Q000150:complications*; D014839:Vomiting / Q000209:etiology
D000889:Anti-Arrhythmia Agents; D002298:Cardenolides; D006027:Glycosides; C008701:oleandrigenin; D004077:Digoxin; C021065:oleandrin