title: Concordance for cloacal dysgenesis.
abstract: Monozygotic (MZ) twins concordant for cloacal dysgenesis were diagnosed at 15 weeks' gestation on ultrasound exam. The structural alterations result from abnormal morphogenesis of the cloacal membrane and contiguous anlage with resultant secondary changes. These defects are suggestive of teratogen exposure or an endogenous event early in gestation, resulting in MZ twinning and the development of a polytopic field defect.
authors.affiliation: Department of Obstetrics and Gynecology, Hutzel Hospital/Wayne State University, Detroit, Mich. 48201, USA.
authors.forename: R L
authors.initials: RL
authors.lastname: Kramer
authors.forename: M P
authors.initials: MP
authors.lastname: Johnson
authors.forename: F
authors.initials: F
authors.lastname: Qureshi
authors.forename: S M
authors.initials: SM
authors.lastname: Jacques
authors.forename: Y
authors.initials: Y
authors.lastname: Yaron
authors.forename: M I
authors.initials: MI
authors.lastname: Evans
mesh_terms: D002988:Cloaca / Q000002:abnormalities* / Q000473:pathology*; D005260:Female; D005313:Fetal Death / Q000473:pathology*; D006801:Humans; D008297:Male; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011272:Pregnancy, Multiple; D014430:Twins, Monozygotic