title: [Impact of controlled pressure on ciliary transport in the nasal epithelium].
abstract: Sinus catheters (RMNK) create positive and negative pressure in the nasal cavity. With control of this pressure, it is possible to remove abnormal secretion from different paranasal sinuses and to insert diagnostic and therapeutic medicines. Saccharine tests performed prior to and after the catheterization in patients with acute and chronic sinusitis confirmed inhibition of transport function of nasal ciliated epithelium (TF) in these affections. Intermittent pressure, insertion of drugs into the nasal cavity and paranasal sinusitis suppress TF significantly in chronic but insignificantly in acute sinusitis. Within 3 hours after the procedure the pressure recovered.
authors.affiliation: Rinologicheskiĭ tsentr Iaroslavskoĭ oblastnoĭ klinicheskoĭ bol'nitsy.
authors.forename: V S
authors.initials: VS
authors.lastname: Kozlov
authors.forename: L L
authors.initials: LL
authors.lastname: Derzhavina
mesh_terms: D000293:Adolescent; D000328:Adult; D002908:Chronic Disease; D004848:Epithelium; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009079:Mucociliary Clearance / Q000502:physiology*; D009297:Nasal Mucosa / Q000502:physiology*; D011312:Pressure; D012439:Saccharin; D012852:Sinusitis
chemical_list: D012439:Saccharin