title: Asymptomatic HIV-infected women: preliminary study of quantitative EEG activity and performance on a continuous performance test.
abstract: Several studies have examined the electrophysiological correlates of human immunodeficiency virus (HIV) infection in medically asymptomatic men. Although the rates of HIV infection are increasing at a greater rate in women than men, there have been no publications to date of electrophysiological functioning in HIV-infected women. In the present study, quantitative electroencephalographic (qEEG) activity was measured in 22 women (11 asymptomatic HIV-seropositive and 11 HIV-seronegative) utilizing a procedure comprised of three auditory continuous performance tests and a set of qEEG components derived from principal components analysis. No significant group differences were found in qEEG or in performance on the continuous performance tests; however, task-related differences were detected across groups between simple and complex language tasks in EEG fast beta power, delta power, and a left-hemisphere principal components analysis-derived EEG component. In examining the electrophysiological correlates of HIV infection, researchers might employ a similar methodology while increasing the sample size and varying the task modality or difficulty.
authors.affiliation: Department of Psychiatry, University of Connecticut Health Center School of Medicine, Farmington, CT 06030-2103, USA. costa@psychiatry.uchc.edu
authors.forename: L
authors.initials: L
authors.lastname: Costa
authors.forename: J E
authors.initials: JE
authors.lastname: Arruda
authors.forename: R A
authors.initials: RA
authors.lastname: Stern
authors.forename: J A
authors.initials: JA
authors.lastname: Somerville
authors.forename: D
authors.initials: D
authors.lastname: Valentino
mesh_terms: D000328:Adult; D001288:Attention / Q000502:physiology*; D001307:Auditory Perception / Q000502:physiology*; D001921:Brain / Q000503:physiopathology; D004569:Electroencephalography / Q000379:methods* / Q000706:statistics & numerical data; D005260:Female; D007839:Functional Laterality / Q000502:physiology; D015658:HIV Infections / Q000175:diagnosis* / Q000503:physiopathology; D018023:HIV Seronegativity; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010700:Phonetics; D011597:Psychomotor Performance / Q000502:physiology*; D011930:Reaction Time / Q000502:physiology; D012660:Semantics; D012737:Sex Factors