title: Laser In Situ keratomileusis (LASIK) for the treatment of low moderate, and high myopia.
abstract: OBJECTIVE
  To evaluate the efficacy, safety and predictability of LASIK in the treatment of low, moderate and high myopia.
  
  
  METHODS
  A perspective study of LASIK for low myopia of -0.75 to -6.00 with less than +1 D of astigmatism and for moderate and high myopia of -6.12 to -20 D with astigmatism up to +4.50 D was performed at our institution from March through November, 1996. The Chiron automated corneal shaper was used for the initial flap, and either the Summit or VISX laser was used for the refractive ablation. Preoperative refraction, uncorrected and corrected visual acuity were compared to postoperative refraction, uncorrected and corrected visual acuity. One day and 1 month results were available on all patients.
  
  
  RESULTS
  In the low myopia group 101 eyes underwent LASIK with a mean preoperative spherical equivalent of -4.16 +/- 1.41 D (-0.75 D to -6.00 D). Mean preoperative astigmatism was +0.4 +/- 1.29 D (0 to 0.75 D). At 1 day, 48% were 20/25 or better and 80% were 20/40 or better. The day 1 mean spherical equivalent was +0.4 +/- 0.75 D with 86% between +/- 1.00 D of emmetropia. At 1 month, 50% were 20/25 or better and 90% were 20/40 or better. The 1 month mean spherical equivalent was -0.26 +/- 0.65 D with 89% between +/- 1.00 D of emmetropia. In the high myopia group 198 eyes underwent LASIK with a preoperative mean spherical equivalent of -8.34 +/- 2.15 D)-6 to -20D) and a mean preoperative astigmatism of +1.18 +/- 0.88 D (0 to +4.5 D). At 1 day postoperatively, 17% were 20/25 or better, and 61% were 20/40 or better. The mean day one spherical equivalent was -0.26 +/- 1.56 D with 58% between +/- 1.00 D of emmetropia. At 1 month, 35% were 20/25 or better and 71% were 20/40 or better. The 1 month mean spherical equivalent was -0.28 +/- 1.18 with 63% within +/- 1.00 D of emmetropia.
  
  
  CONCLUSIONS
  Early results of using LASIK to treat low, moderate and high degrees of myopia with and without astigmatism appear promising, although longer follow-up and nomogram refinement are needed.
authors.affiliation: Phillips Eye Institute, Minneapolis, Minnesota, USA.
authors.forename: R L
authors.initials: RL
authors.lastname: Lindstrom
authors.forename: D R
authors.initials: DR
authors.lastname: Hardten
authors.forename: Y R
authors.initials: YR
authors.lastname: Chu
mesh_terms: D000328:Adult; D001251:Astigmatism / Q000150:complications; D003315:Cornea / Q000503:physiopathology / Q000601:surgery*; D016039:Corneal Transplantation / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy; D009216:Myopia / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D011183:Postoperative Complications; D011446:Prospective Studies; D012029:Refraction, Ocular; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology