title: [Pure red cell aplasia, associated with chronic lymphoid leukemia, successfully treated with closorine].
abstract: Pure red cell aplasia (PRCA) is a rare disorder, which is characterized by severe anaemia associated with reticulocytopenia and absence of erythroid precursor cell from the bone marrow. Mostly immunological mechanisms have a role in its pathogenesis. Primarily the acquired, idiopathic type occurs in adults, however, it is rarely associated with other disorders (autoimmune-, and lymphoproliferative diseases, etc.). The authors present a patient with B-cell chronic lymphocytic leukemia associated with PRCA, which was successfully treated with cyclosporine. The pathogenesis and the therapy of the PRCA is also summarized.
authors.affiliation: Debreceni Orvostudományi Egyetem, II. sz. Belklinika.
authors.forename: K
authors.initials: K
authors.lastname: Rácz
authors.forename: B
authors.initials: B
authors.lastname: Telek
authors.forename: G
authors.initials: G
authors.lastname: Ujj
authors.forename: A
authors.initials: A
authors.lastname: Kiss
authors.forename: K
authors.initials: K
authors.lastname: Rák
authors.forename: M
authors.initials: M
authors.lastname: Udvardy
mesh_terms: D016572:Cyclosporine / Q000627:therapeutic use*; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D012010:Red-Cell Aplasia, Pure / Q000150:complications* / Q000188:drug therapy
chemical_list: D016572:Cyclosporine