title: [Recombinant tissue plasminogen activator in treatment of fulminant meningococcal infection].
abstract: This article reports about a young boy with fulminant meningococcal septicemia. Conventional treatment with antibiotics, intensive care and hemostatic drugs hold up vital functions. Because of extensive purpura fulminans with skin necrosis recombinant tissue plasminogen activator (rt-PA) was used. Under this therapy clinical improvement was observed.
authors.affiliation: Abteilung für pädiatrische Intensivmedizin und Neonatologie, Universität Witten/Herdecke.
authors.forename: K
authors.initials: K
authors.lastname: Winter
authors.forename: C
authors.initials: C
authors.lastname: Noppeney
authors.forename: G
authors.initials: G
authors.lastname: Thom
authors.forename: K
authors.initials: K
authors.lastname: Runge
mesh_terms: D002675:Child, Preschool; D003131:Combined Modality Therapy; D003422:Critical Care; D006801:Humans; D008297:Male; D008589:Meningococcal Infections / Q000175:diagnosis / Q000628:therapy*; D009336:Necrosis; D011994:Recombinant Proteins / Q000008:administration & dosage; D018805:Sepsis / Q000175:diagnosis / Q000628:therapy*; D012867:Skin / Q000473:pathology; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage*
chemical_list: D011994:Recombinant Proteins; D010959:Tissue Plasminogen Activator