title: Item assessment in the development of a diagnostic motor performance test for myopathy in children.
abstract: The authors conducted an assessment study of newly developed motor performance items for the diagnosis of myopathy. 17 children who had had muscle biopsy for this diagnosis in the recent past were administered 14 items based on the measurement of static, dynamic and explosive muscle strength and muscle endurance. Individual items did not have perfect discriminative power, but the results were encouraging enough to warrant detailed study with combinations of the items, so that in future fewer children will have to undergo unnecessary muscle biopsies.
authors.affiliation: Department of Medical Informatics and Epidemiology, University of Nijmegen, The Netherlands.
authors.forename: Y T
authors.initials: YT
authors.lastname: van der Schouw
authors.forename: W A
authors.initials: WA
authors.lastname: van den Beld
authors.forename: G A
authors.initials: GA
authors.lastname: van der Sanden
authors.forename: R A
authors.initials: RA
authors.lastname: Binkhorst
authors.forename: F J
authors.initials: FJ
authors.lastname: Gabreëls
authors.forename: A L
authors.initials: AL
authors.lastname: Verbeek
mesh_terms: D001706:Biopsy; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009048:Motor Skills / Q000145:classification*; D018482:Muscle, Skeletal / Q000473:pathology; D009460:Neurologic Examination / Q000379:methods; D009468:Neuromuscular Diseases / Q000175:diagnosis*; D012680:Sensitivity and Specificity