title: Vitamin A status and therapy in childhood pulmonary tuberculosis.
abstract: Low plasma vitamin A levels (mean, 18.1 +/- 10.3 micrograms/dl, 62% below normal) were demonstrated in South African children with pulmonary tuberculosis. More extensive or severe disease (e.g., additional extrapulmonary tuberculosis) and low levels of retinol binding protein, prealbumin, and albumin were associated with low vitamin A levels. High-dose vitamin A therapy had no effect on disease outcome.
authors.affiliation: Department of Paediatrics and Child Health, University of Cape Town, South Africa.
authors.forename: W A
authors.initials: WA
authors.lastname: Hanekom
authors.forename: S
authors.initials: S
authors.lastname: Potgieter
authors.forename: E J
authors.initials: EJ
authors.lastname: Hughes
authors.forename: H
authors.initials: H
authors.lastname: Malan
authors.forename: G
authors.initials: G
authors.lastname: Kessow
authors.forename: G D
authors.initials: GD
authors.lastname: Hussey
mesh_terms: D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D012044:Regression Analysis; D013019:South Africa; D014397:Tuberculosis, Pulmonary / Q000097:blood / Q000628:therapy*; D014801:Vitamin A / Q000097:blood / Q000627:therapeutic use*
chemical_list: D014801:Vitamin A