title: Are single-needle protocols equivalent to dual-needle protocols for platelet apheresis?
abstract: In light of the increasing demands being placed on cytapheresis donors and their occasional venous problems, it has become necessary to use 1-needle in addition to 2-needle separation techniques in thrombocytapheresis. We therefore compared five 1-needle and three 2-needle programs on four different cell separators and found that meanwhile both the platelet yields and the leukopenia (controlled by Nageotte chamber counting) of the products obtained with the 1-needle technique are equivalent to those obtained using the 2-needle technique, as long as the program is suitably adjusted.
authors.affiliation: Abteilung für Transfusionsmedizin, Friedrich-Alexander-Universität Erlangen, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Zingsem
authors.forename: V
authors.initials: V
authors.lastname: Weisbach
authors.forename: T
authors.initials: T
authors.lastname: Zeiler
authors.forename: R
authors.initials: R
authors.lastname: Zimmermann
authors.forename: B
authors.initials: B
authors.lastname: Neidhardt
authors.forename: R
authors.initials: R
authors.lastname: Eckstein
mesh_terms: D001772:Blood Cell Count; D006801:Humans; D007962:Leukocytes; D009339:Needles; D010983:Plateletpheresis / Q000295:instrumentation* / Q000379:methods*; D014019:Tissue Donors