Do calcium-channel blockers and glucocorticoids impair no production in ischaemic heart disease patients?
Calcium channel blockers, as glucocorticoids, may impair generation of NO in vivo, because of urinary nitrates deficit in spite of nitrated derivatives treatment in ischaemic heart disease patients.
Giroux
M
M
Ferrières
J
J
Salles
J P
JP
D002121:Calcium Channel Blockers / Q000009:adverse effects* / Q000627:therapeutic use; D005938:Glucocorticoids / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D017202:Myocardial Ischemia / Q000188:drug therapy*; D009569:Nitric Oxide / Q000378:metabolism / Q000652:urine*; D019001:Nitric Oxide Synthase / Q000037:antagonists & inhibitors* / Q000187:drug effects; D012016:Reference Values; D016482:Urinalysis
D002121:Calcium Channel Blockers; D005938:Glucocorticoids; D009569:Nitric Oxide; D019001:Nitric Oxide Synthase