title: A case of idiopathic anaphylaxis associated with respiratory infections.
abstract: BACKGROUND
  Anaphylaxis is associated with IgE-mediated reactions to foods, drugs, and other allergens. Exercise-induced anaphylaxis and food plus exercise-induced anaphylaxis have been reported. Anaphylactoid reactions with no mechanisms determined have been described with radiographic contrast media. Idiopathic anaphylaxis by definition is anaphylaxis with no identifiable external allergen or stimulus. In our series of more than 350 patients with idiopathic anaphylaxis, extensive evaluation has failed to identify a cause for the anaphylaxis.
  
  
  OBJECTIVE
  To report a first case of idiopathic anaphylaxis associated with coryzal symptoms.
  
  
  METHODS
  A patient was evaluated for idiopathic anaphylaxis. Appropriate therapy was initiated.
  
  
  RESULTS
  The patient's anaphylactic episodes are related to the occurrence of coryzal symptoms but no clear IgE-mediated mechanism was identified.
  
  
  CONCLUSIONS
  This is the first reported association of anaphylaxis with an inciting factor of infection.
authors.affiliation: Division of Allergy-Immunology, Northwestern University Medical School, Chicago, Illinois, USA.
authors.forename: N
authors.initials: N
authors.lastname: Mazur
authors.forename: R
authors.initials: R
authors.lastname: Patterson
authors.forename: D
authors.initials: D
authors.lastname: Perlman
mesh_terms: D000707:Anaphylaxis / Q000209:etiology*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D008875:Middle Aged; D012141:Respiratory Tract Infections / Q000150:complications*
chemical_list: D007073:Immunoglobulin E