title: The assessment of value of transvaginal ultrasound for monitoring of gestational trophoblastic disease treatment.
abstract: Thirtysix patients with persistent gestational trophoblastic disease were analysed in The Clinic of Cancer of Female Reproductive System. Using transvaginal USG, the volume of pathological foci within myometrium, diametre of theca lutein ovarian cysts and uterus length before, during and after the treatment were registred. In order to check the effectiveness of USG examination in the monitoring of GTD treatment particular USG factors were compared with hCG level. On 28 patients (77.7%) in USG examination pathological changes in uterus and ovaries were seen. The relation between hCG level and tumor volume, uterus length and theca lutein ovarian cysts was stated. That proves the usefulness of transvaginal USG examination in the monitoring of treatment of patients with persistent gestational trophoblastic disease.
authors.affiliation: Clinic of Cancer of Female Reproductive System, Centre of Oncology, Warsaw, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Bidziñski
authors.forename: B
authors.initials: B
authors.lastname: Lemieszczuk
authors.forename: M
authors.initials: M
authors.lastname: Drabik
mesh_terms: D000328:Adult; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage / Q000627:therapeutic use*; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000627:therapeutic use*; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage / Q000627:therapeutic use*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D006063:Chorionic Gonadotropin / Q000097:blood; D003609:Dactinomycin / Q000008:administration & dosage / Q000627:therapeutic use*; D005047:Etoposide / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008727:Methotrexate / Q000008:administration & dosage / Q000627:therapeutic use*; D008991:Monitoring, Physiologic / Q000379:methods; D010053:Ovary / Q000000981:diagnostic imaging; D011247:Pregnancy; D014328:Trophoblastic Neoplasms / Q000097:blood / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D014463:Ultrasonography; D014594:Uterine Neoplasms / Q000097:blood / Q000000981:diagnostic imaging* / Q000188:drug therapy*; D014599:Uterus / Q000033:anatomy & histology / Q000000981:diagnostic imaging
chemical_list: D000903:Antibiotics, Antineoplastic; D000964:Antimetabolites, Antineoplastic; D000972:Antineoplastic Agents, Phytogenic; D006063:Chorionic Gonadotropin; D003609:Dactinomycin; D005047:Etoposide; D008727:Methotrexate