DNA adduct levels in rapid and slow acetylator inbred rats administered 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
Fretland
A J
AJ
Department of Pharmacology and Toxicology, University of North Dakota School of Medicine and Health Sciences, Grand Forks 58202, USA.
Feng
Y
Y
Hein
D W
DW
D000818:Animals; D001191:Arylamine N-Acetyltransferase / Q000378:metabolism; D002274:Carcinogens, Environmental / Q000493:pharmacokinetics / Q000633:toxicity*; D018736:DNA Adducts / Q000378:metabolism*; D003849:Deoxyguanosine / Q000031:analogs & derivatives / Q000378:metabolism; D007093:Imidazoles / Q000378:metabolism* / Q000493:pharmacokinetics / Q000633:toxicity; D008297:Male; D009153:Mutagens / Q000378:metabolism* / Q000493:pharmacokinetics / Q000633:toxicity; D010641:Phenotype; D011110:Polymorphism, Genetic; D051381:Rats; D011916:Rats, Inbred F344; D011921:Rats, Inbred WKY; D014018:Tissue Distribution
D002274:Carcinogens, Environmental; D018736:DNA Adducts; D007093:Imidazoles; D009153:Mutagens; C078255:N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; C049584:2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; D001191:Arylamine N-Acetyltransferase; D003849:Deoxyguanosine