title: [The Wermer syndrome].
abstract: The difficult diagnostic and therapeutic management of patients having gastrinoma with multiple endocrine neoplasia type I (MEN I) has been discussed by reference to the literature and a personal experience of 2 patients with Wermer syndrome. The syndrome is often familial and might be inherited as an autosomal dominant trait with a high but variable degree of penetrance. Pancreatic islets, parathyroid glands and adenohypophyseal [correction of antehypophyseal] cells are the three localization main for endocrine involvement in MEN I syndrome.
authors.affiliation: Clinica I Chirurgie, Spitalul Universitar Sf. Spiridon, Iaşi.
authors.forename: E
authors.initials: E
authors.lastname: Târcoveanu
authors.forename: V
authors.initials: V
authors.lastname: Strat
authors.forename: E
authors.initials: E
authors.lastname: Cotea
authors.forename: V
authors.initials: V
authors.lastname: Filip
authors.forename: E
authors.initials: E
authors.lastname: Zbranca
authors.forename: C
authors.initials: C
authors.lastname: Vulpoi
authors.forename: N
authors.initials: N
authors.lastname: Florea
authors.forename: C
authors.initials: C
authors.lastname: Daniil
authors.forename: F
authors.initials: F
authors.lastname: Crumpei
authors.forename: V
authors.initials: V
authors.lastname: Rusu
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D015408:Gastrinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D018761:Multiple Endocrine Neoplasia Type 1 / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010282:Parathyroid Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010437:Peptic Ulcer / Q000175:diagnosis / Q000473:pathology / Q000601:surgery; D012008:Recurrence; D012086:Reoperation