title: Synthesis of some 2-benzoxazolinone derivatives and their analgesic properties.
abstract: In this study, the synthesis and analgesic activities of some new 6-acyl-3-(4-substituted benzoylmethyl)-2-benzoxazolinone derivatives are reported. Their structures were confirmed by microanalysis, IR, and NMR spectral analysis. The obtained compounds were screened for their analgesic activities. Analgesic activity of these compounds was investigated by modified Koster Test. The 11 compounds synthesized showed good analgesic activities.
authors.affiliation: Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Ankara, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Erdogan
authors.forename: S
authors.initials: S
authors.lastname: Eriskon
authors.forename: R
authors.initials: R
authors.lastname: Demirdamar
mesh_terms: D018712:Analgesics, Non-Narcotic / Q000138:chemical synthesis* / Q000494:pharmacology; D000818:Animals; D001583:Benzoxazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D003460:Crystallization; D005260:Female; D051379:Mice
chemical_list: D018712:Analgesics, Non-Narcotic; D001583:Benzoxazoles