title: Evaluation of the MAST CLA allergy system for diagnosis of allergies to house dust mites and cats.
abstract: The MAST CLA system was evaluated against skin prick test (SPT) for diagnosis of allergies to house dust mites (Dermatophagoides pteronyssinus, Dermatophagoides farinae) and cats. Forty three asthmatic children were examined by SPT and MAST CLA. Chi-square analysis indicated significant association between SPT and MAST CLA results for the house dust mites but not for cats. The sensitivities of MAST CLA for house dust mites and cats were 100 and 25% respectively; specificities were all less than 50%. The efficiency of MAST CLA for detection of allergy to the house dust mites was 88% and 44% for cats. A significant linear correlation was found between SPT wheal size and MAST CLA grade for D. farinae but not for D. pteronyssinus and cats. It is concluded that the MAST CLA allergy system can be used to supplement SPT for diagnosis of allergies to house dust mites but not to cats.
authors.affiliation: Institute for Medical Research, Jalan Pahang, Kuala Lumpur, Malaysia.
authors.forename: T M
authors.initials: TM
authors.lastname: Ho
authors.forename: J
authors.initials: J
authors.lastname: DeBruynne
authors.forename: M
authors.initials: M
authors.lastname: Ahamad
authors.forename: H
authors.initials: H
authors.lastname: Darussamin
mesh_terms: D000293:Adolescent; D000485:Allergens; D000818:Animals; D002415:Cats / Q000276:immunology*; D002648:Child; D004391:Dust / Q000009:adverse effects*; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis* / Q000276:immunology; D007118:Immunoassay / Q000379:methods*; D016014:Linear Models; D008163:Luminescent Measurements; D008925:Mites / Q000276:immunology*; D012680:Sensitivity and Specificity; D012882:Skin Tests
chemical_list: D000485:Allergens; D004391:Dust