Feasibility of an obstetrician-based cord blood collection network for unrelated donor umbilical cord blood banking.
The purpose of this study was to evaluate the feasibility of an obstetrician-based cord blood collection system for the purpose of banking cord blood for unrelated donor hematopoietic stem cell transplantation. Over 200 delivering physicians and 40 area obstetrical units were educated and became involved in the collection of cord blood during the third stage of labor. These products compared favorable with those obtained after placental delivery. Issues involved in the development of quality assurance for unrelated donor banking are discussed. An obstetrician-based cord blood collection network is feasible and advantageous in that cord blood can be collected from a wider variety of communities, thus enhancing the ethnic diversity of a bank.
Wall
D A
DA
Department of Pediatrics, St. Louis University Health Sciences Center, Cardinal Glennon Children's Hospital, Missouri 63104, USA.
Noffsinger
J M
JM
Mueckl
K A
KA
Alonso
J M
JM
Regan
D M
DM
Johnson
C E
CE
Weinstein
D L
DL
Duarte
L M
LM
Winn
H N
HN
D001419:Bacteria / Q000302:isolation & purification; D001771:Blood Banks; D001782:Blood Donors; D001800:Blood Specimen Collection; D005240:Feasibility Studies; D005260:Female; D005312:Fetal Blood / Q000382:microbiology; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells; D006801:Humans; D007749:Labor Stage, Third; D009774:Obstetrics; D011247:Pregnancy; D011786:Quality Control