title: [Current status of the treatment of high grade bone sarcomas].
abstract: The authors present a review of the changes occurred in the treatment of high grade bone sarcomas in the last 20 years. It was discussed the multidisciplinary approach for the local and systemic control of these tumors particularly the neoadjuvant chemotherapy that leads to an increase in the overall survival not only for the osteosarcoma but also for the Ewing sarcoma. They showed the possibilities for limb reconstruction after wide resection of the lesion that includes non conventional endoprosthesis and allografts.
authors.affiliation: Departamento de Ortopedia e Traumatologia, Faculdade de Medicina, Universidade de São Paulo.
authors.forename: O P
authors.initials: OP
authors.lastname: de Camargo
authors.forename: A T
authors.initials: AT
authors.lastname: Croci
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D004358:Drug Therapy / Q000639:trends; D006801:Humans; D011379:Prognosis; D011859:Radiography; D012509:Sarcoma / Q000000981:diagnostic imaging / Q000628:therapy*; D013514:Surgical Procedures, Operative / Q000639:trends