The use of glucagon in nifedipine poisoning complicated by clonidine ingestion.
Glucagon has been used to treat the hypotension associated with calcium channel antagonist poisoning in adult patients. We describe the successful use of glucagon in a pediatric patient poisoned with nifedipine and clonidine whose hypotension was unresponsive to fluid resuscitation, calcium chloride, and dopamine.
Fant
J S
JS
Section of Pediatric Clinical Pharmacology, University of Arkansas for Medical Sciences, Little Rock, USA.
James
L P
LP
Fiser
R T
RT
Kearns
G L
GL
D000293:Adolescent; D000931:Antidotes / Q000627:therapeutic use*; D000959:Antihypertensive Agents / Q000506:poisoning*; D002121:Calcium Channel Blockers / Q000506:poisoning*; D003000:Clonidine / Q000506:poisoning*; D004347:Drug Interactions; D062787:Drug Overdose; D005260:Female; D005934:Glucagon / Q000627:therapeutic use*; D006801:Humans; D009543:Nifedipine / Q000506:poisoning*; D011041:Poisoning / Q000188:drug therapy
D000931:Antidotes; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D005934:Glucagon; D009543:Nifedipine; D003000:Clonidine