title: Does pulmonary tuberculosis change with ageing?
abstract: METHODS
  In most low prevalence countries, tuberculosis has become a disease of the aged; it has recently been suggested that the elderly may present a specific pattern.
  
  
  OBJECTIVE
  To compare clinical, bacteriological and radiological features of pulmonary tuberculosis between young and elderly populations in a high incidence country.
  
  
  METHODS
  We retrospectively studied 337 consecutive pulmonary tuberculosis patients without confirmed HIV infection, hospitalised from 1989 to 1993. The clinical, bacteriological and radiological features of the two age groups considered, young adults (< 60 years) and elderly (> or = 60 years), were compared.
  
  
  RESULTS
  Thoracic pain (16.3% vs 32.7%) and fever (27.2% vs 50.6%) were significantly less frequent in the elderly, while the frequency and duration of other symptoms before hospitalisation were similar. After admission, fever remained longer in young patients (P < 0.05). No significant differences were found regarding the general health status at hospitalisation, or associated illnesses (83.7% vs 73.5%; P = 0.068). Radiological lesions not related to the present diagnosis (14.1% vs 2.0%; P < 0.05), and a presumed diagnosis of tuberculosis (11.7% vs 4.1%; P = 0.02) were more frequent in the elderly.
  
  
  CONCLUSIONS
  This study showed no specific clinical, bacteriological or radiological features between age groups, and does not support the hypothesis of any age-related patterns in pulmonary tuberculosis.
authors.affiliation: Serviço de Pneumologia, Hospital Joaquim Urbano, Faculdade de Medicina do Porto, Portugal.
authors.forename: M
authors.initials: M
authors.lastname: Rocha
authors.forename: S
authors.initials: S
authors.lastname: Pereira
authors.forename: H
authors.initials: H
authors.lastname: Barros
authors.forename: J
authors.initials: J
authors.lastname: Seabra
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000375:Aging; D018450:Disease Progression; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D011174:Portugal / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology