title: [Acute severe hypersensitivity reaction to salazopirin].
abstract: Sulphasalazine is the drug most widely used in intestinal inflammatory disease given its efficacy and low cost. Nonetheless, its administration is not lacking adverse effects. Two cases of severe hypersensitivity are herein described. Moreover, the diagnostic difficulties observed and their implication in the management of the underlying disease are discussed.
authors.affiliation: Servicio de Aparato Digestivo, Hospital Universitario Virgen del Rocio, Sevilla.
authors.forename: S
authors.initials: S
authors.lastname: Otero
authors.forename: J
authors.initials: J
authors.lastname: Larrauri
authors.forename: J M
authors.initials: JM
authors.lastname: Herrera
authors.forename: A
authors.initials: A
authors.lastname: Pizarro
authors.forename: E
authors.initials: E
authors.lastname: García
authors.forename: A
authors.initials: A
authors.lastname: Guil
authors.forename: C
authors.initials: C
authors.lastname: Crivell
authors.forename: J M
authors.initials: JM
authors.lastname: Cisneros
mesh_terms: D000328:Adult; D003229:Conjunctival Diseases / Q000139:chemically induced; D003967:Diarrhea / Q000188:drug therapy; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D005765:Gastrointestinal Agents / Q000009:adverse effects*; D006801:Humans; D007565:Jaundice / Q000139:chemically induced; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy; D012460:Sulfasalazine / Q000009:adverse effects
chemical_list: D005765:Gastrointestinal Agents; D012460:Sulfasalazine