Regression of superficial gastric MALT lymphoma with unsuccessful eradication therapy for Helicobacter pylori infection.
A 51-year-old man had a reddish flat granular lesion in the stomach on endoscopic examination. Histology of biopsied specimen confirmed the diagnosis of low-grade B-cell gastric lymphoma of mucosa-associated lymphoid tissue (gastric MALT lymphoma) and simultaneous infection with Helicobacter pylori. He was given antibiotic treatment. Five weeks later, endoscopy and histology of biopsied specimen showed eradication of H. pylori, and the tumor had regressed. Six months later, H. pylori reemerged, but the tumor had not recurred. After the second antibiotic therapy, H. pylori has been eradicated. The lymphoma has been in remission for 14 months.
Yoshikane
H
H
Department of Internal Medicine, Handa City Hospital, Aichi, Japan.
Yokoi
T
T
Hidano
H
H
Sakakibara
A
A
Niwa
Y
Y
Goto
H
H
D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001706:Biopsy; D015139:Blotting, Southern; D004724:Endoscopy; D016481:Helicobacter Infections / Q000150:complications / Q000188:drug therapy*; D016480:Helicobacter pylori; D006801:Humans; D007143:Immunoglobulin Heavy Chains / Q000235:genetics; D007147:Immunoglobulin Light Chains / Q000235:genetics; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014463:Ultrasonography
D000900:Anti-Bacterial Agents; D007143:Immunoglobulin Heavy Chains; D007147:Immunoglobulin Light Chains