title: Immunoglobulin G in the developing oocytes of the domestic hen and immunospecific antibody response in serum and corresponding egg yolk.
abstract: The concentration of Immunoglobulin G (IgG) in developing oocytes from normal chickens was measured by ELISA. The concentration was similar in oocytes ranging in size from 6 mm to 38 mm, which is in the last stage of development before ovulation. The concentration of immunospecific IgG was similar in corresponding serum and yolk samples in chickens immunised with human IgG, and a significant linear correlation between response of a specific antibody in the serum and corresponding egg yolk was found. The serum antibody level had to reach a certain level before specific antibody appeared in the egg yolk, and the egg yolk to a certain extent reflected the serum concentration of IgG over 6 to 7 days; because this is the time it takes for the developing oocyte to grow from 6 to 35 mm in diameter.
authors.affiliation: Scantox, Lille Skensved, Denmark.
authors.forename: L S
authors.initials: LS
authors.lastname: Bollen
authors.forename: J
authors.initials: J
authors.lastname: Hau
mesh_terms: D000818:Animals; D002645:Chickens; D004530:Egg Yolk / Q000276:immunology*; D007074:Immunoglobulin G / Q000378:metabolism*; D009865:Oocytes / Q000276:immunology*
chemical_list: D007074:Immunoglobulin G