title: (-)-formoterol, a selective beta 2-adrenoreceptor agonist.
abstract: The crystal structure of (-)-formoterol [2-hydroxy- 5-(hydroxy-2-¿[2-(p-methoxyphenyl)-1-methylethyl]- amino¿ethyl)formanilide (+)-tartrate, C19H25N2O4+.C4H5O6-] has been determined in order to elucidate its configuration relative to that of (+)-tartrate. The result is consistent with the configuration proposed on the basis of the chemical correlation experiments.
authors.affiliation: Institute for Drug Discovery Research, Yamanouchi Pharmaceutical Co., Ltd., Ibaraki, Japan. kurihara@yamanouchi.co.jp
authors.forename: H
authors.initials: H
authors.lastname: Kurihara
authors.forename: S
authors.initials: S
authors.lastname: Fujita
authors.forename: T
authors.initials: T
authors.lastname: Mase
mesh_terms: D000318:Adrenergic beta-Agonists / Q000737:chemistry*; D003460:Crystallization; D018360:Crystallography, X-Ray; D004983:Ethanolamines / Q000737:chemistry*; D000068759:Formoterol Fumarate; D006860:Hydrogen Bonding; D015394:Molecular Structure; D013237:Stereoisomerism
chemical_list: D000318:Adrenergic beta-Agonists; D004983:Ethanolamines; D000068759:Formoterol Fumarate