Disseminated infection with Bacillus Calmette-Guerin in a child with advanced HIV disease.
An 8-month-old boy with vertically acquired HIV-infection who developed a disseminated BCG infection is described. The patient had been immunized at birth with BCG. In spite of a normal CD-4 lymphocyte count, he suffered from fever, anaemia and failure to thrive. BCG was isolated by culture from CSF, bone marrow and peripheral blood. Anti-tuberculous treatment initially seemed successful, but shortly after, the patient died from Pneumocystis carinii pneumonia. In symptomatic HIV-infected children originating from countries with BCG immunization programs, disseminated BCG infection should be considered.
Rosenfeldt
V
V
University Clinic of Paediatrics, Hvidovre Hospital, Denmark.
Paerregaard
A
A
Valerius
N H
NH
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis / Q000209:etiology*; D001500:BCG Vaccine / Q000009:adverse effects* / Q000276:immunology; D015658:HIV Infections / Q000276:immunology* / Q000382:microbiology; D006801:Humans; D007223:Infant; D008297:Male; D009164:Mycobacterium Infections / Q000175:diagnosis / Q000209:etiology*; D009163:Mycobacterium bovis / Q000302:isolation & purification*; D014611:Vaccination / Q000009:adverse effects
D001500:BCG Vaccine