title: Autocatalytic removal of the pro-sequence from kexins requires an intact P-domain.
authors.affiliation: Department of Biological Sciences, University of Warwick, Coventry, UK. PDJT@dna.bio.warwick.ac.uk
authors.forename: D
authors.initials: D
authors.lastname: Powner
authors.forename: J
authors.initials: J
authors.lastname: Davey
mesh_terms: D000409:Alanine; D019943:Amino Acid Substitution; D000818:Animals; D001665:Binding Sites; D002384:Catalysis; D002474:Cell-Free System; D005260:Female; D016297:Mutagenesis, Site-Directed; D009865:Oocytes / Q000502:physiology; D043484:Proprotein Convertases; D014176:Protein Biosynthesis; D011499:Protein Processing, Post-Translational; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000737:chemistry / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins; D012568:Schizosaccharomyces / Q000201:enzymology*; D012694:Serine; D013381:Subtilisins / Q000096:biosynthesis / Q000737:chemistry* / Q000378:metabolism*; D014981:Xenopus
chemical_list: D011994:Recombinant Proteins; D029701:Saccharomyces cerevisiae Proteins; D012694:Serine; D043484:Proprotein Convertases; D013381:Subtilisins; C091268:krp dibasic endopeptidase; C058751:KEX2 protein, S cerevisiae; D000409:Alanine