title: Posthypoxic myoclonus in intensive care.
abstract: Posthypoxic myoclonus (Lance-Adams' syndrome) is a rare complication of cardiorespiratory arrest. It has a better prognosis than other movement disorders secondary to brain ischaemia. We report a case of posthypoxic myoclonus in a 66-year-old woman after acute myocardial infarction and cardiopulmonary arrest. She had action and intention myoclonus, and these movements were also initiated by acoustic and pain stimuli. The origin of the myoclonus was probably subcortical, and it improved with clonazepam 2 mg t.i.d. We emphasize that early diagnosis is necessary in intensive care units in order to avoid misinterpretation of this syndrome and to start appropriate treatment.
authors.affiliation: Department of Internal Medicine, Hospital Clínic i Provincial, Barcelona, Spain.
authors.forename: O
authors.initials: O
authors.lastname: Miró
authors.forename: A
authors.initials: A
authors.lastname: Chamorro
authors.forename: M
authors.initials: M
authors.lastname: del Mar Lluch
authors.forename: P
authors.initials: P
authors.lastname: Nadal
authors.forename: J
authors.initials: J
authors.lastname: Millá
authors.forename: A
authors.initials: A
authors.lastname: Urbano-Márquez
mesh_terms: D000368:Aged; D000927:Anticonvulsants / Q000627:therapeutic use; D016887:Cardiopulmonary Resuscitation / Q000009:adverse effects*; D002998:Clonazepam / Q000627:therapeutic use; D003422:Critical Care; D005260:Female; D005500:Follow-Up Studies; D006323:Heart Arrest / Q000209:etiology* / Q000628:therapy; D006801:Humans; D002534:Hypoxia, Brain / Q000150:complications* / Q000628:therapy; D008577:Meningeal Neoplasms / Q000150:complications; D008579:Meningioma / Q000150:complications; D009203:Myocardial Infarction / Q000150:complications / Q000628:therapy; D009207:Myoclonus / Q000188:drug therapy / Q000209:etiology*; D013577:Syndrome
chemical_list: D000927:Anticonvulsants; D002998:Clonazepam