Antihelminthic drugs in diffuse unilateral subacute neuroretinitis.
OBJECTIVE
To evaluate the efficacy of ivermectin and thiabendazole in confirmed cases of diffuse unilateral subacute neuroretinitis.


METHODS
Two patients with diffuse unilateral subacute neuroretinitis were treated with anthelminthic drugs. The first patient was treated with ivermectin and the second, with thiabendazole.


RESULTS
The worms were still mobile after treatment with ivermectin or thiabendazole. With the application of photocoagulation, the organisms were destroyed, and the patients' vision improved.


CONCLUSIONS
In these two patients, ivermectin and thiabendazole were not effective in treating confirmed diffuse unilateral subacute neuroretinitis.
Casella
A M
AM
Department of Ophthalmology, State University of Londrina, Brazil. mcasella@sercomtel.com.br
Farah
M E
ME
Belfort
R
R
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000871:Anthelmintics / Q000627:therapeutic use*; D015822:Eye Infections, Parasitic / Q000469:parasitology / Q000473:pathology / Q000628:therapy*; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D007559:Ivermectin / Q000627:therapeutic use; D017075:Laser Coagulation; D008297:Male; D009902:Optic Neuritis / Q000469:parasitology / Q000473:pathology / Q000628:therapy*; D011528:Protozoan Infections / Q000469:parasitology / Q000473:pathology / Q000628:therapy*; D012160:Retina / Q000469:parasitology; D012173:Retinitis / Q000469:parasitology / Q000473:pathology / Q000628:therapy*; D013827:Thiabendazole / Q000627:therapeutic use; D014792:Visual Acuity
D000871:Anthelmintics; D007559:Ivermectin; D013827:Thiabendazole