False-positive somatostatin receptor scintigraphy due to an accessory spleen.
A patient with previous left caudal pancreatectomy and splenectomy presented with Zollinger-Ellison syndrome. Abdominal CT and endoscopic ultrasonography revealed a mass in the splenic area. Somatostatin receptor scintigraphy showed a nodular increase of the uptake corresponding to the lesion detected with conventional imaging. A second laparotomy was performed and the mass was resected. Histological analysis showed that the nodular lesion was an accessory spleen. Since physiologic uptake of 111In-pentetreotide is seen in the spleen, an accessory spleen mimicking a tumor, specially after previous splenectomy, may result in false-positive somatostatin receptor scintigraphy.
Lebtahi
R
R
Nuclear Medicine, Department, Bichat Hospital, Paris, France.
Cadiot
G
G
Marmuse
J P
JP
Vissuzaine
C
C
Petegnief
Y
Y
Courillon-Mallet
A
A
Cattan
D
D
Mignon
M
M
Le Guludec
D
D
D005189:False Positive Reactions; D006801:Humans; D007205:Indium Radioisotopes; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D017481:Receptors, Somatostatin / Q000032:analysis*; D013004:Somatostatin / Q000031:analogs & derivatives*; D013154:Spleen / Q000002:abnormalities* / Q000000981:diagnostic imaging; D015043:Zollinger-Ellison Syndrome / Q000000981:diagnostic imaging*
D007205:Indium Radioisotopes; D017481:Receptors, Somatostatin; D013004:Somatostatin; C081788:pentetreotide