Hepatoblastoma incidence in the United States from 1973 to 1992.
BACKGROUND
There is recent evidence to suggest that extremely low birth weight is associated with the occurrence of hepatoblastoma.


METHODS
In light of this possibility, we evaluated trends in hepatoblastoma incidence in the United States among children age 4 years and younger.


RESULTS
We found an increasing trend (5.2%) in hepatoblastoma incidence over the past two decades, a period that corresponds with improved survival of very low birth weight children.


CONCLUSIONS
Future studies of hepatoblastoma that incorporate birth weight are appropriate.
Ross
J A
JA
Department of Pediatrics, University of Minnesota, Minneapolis 55455, USA. ross@epivax.epi.umn.edu
Gurney
J G
JG
D002675:Child, Preschool; D005260:Female; D018197:Hepatoblastoma / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007223:Infant; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D008113:Liver Neoplasms / Q000453:epidemiology*; D008297:Male; D014481:United States / Q000453:epidemiology