Genetic characterization of late-flowering traits induced by DNA hypomethylation mutation in Arabidopsis thaliana.
Arabidopsis DNA hypomethylation mutation, ddm1, results in a variety of developmental abnormalities by slowly inducing heritable lesions at unlinked loci. Here, late-flowering traits observed at high frequencies in independently-established ddm1 lines were genetically characterized. In all of the four late-flowering lines examined the traits were dominant and mapped to the same chromosomal region, which is close or possibly identical to the FWA locus. The ddm1-induced phenotypic onsets are apparently not random mutation events, but specific to a group of genes, suggesting the underlying epigenetic mechanism. The DNA methylation mutant provide useful system for identifying epigenetically-regulated genes important for plant development.
Kakutani
T
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Department of Molecular Genetics, National Institute of Agrobiological Resources, Ibaraki, Japan. kakutani@abr.affrc.go.jp
D017360:Arabidopsis / Q000235:genetics / Q000502:physiology*; D003433:Crosses, Genetic; D019175:DNA Methylation; D018744:DNA, Plant / Q000737:chemistry / Q000235:genetics; D009154:Mutation; D010641:Phenotype; D018547:Plant Stems
D018744:DNA, Plant