title: Characterization of two class I genes from the H2-M region: evidence for a new subfamily.
abstract: We cloned, sequenced, and mapped two divergent major histocompatibility class Ib genes from BALB/c mice. M9d and M10d both have the potential to encode full-length class I molecules, but transcripts were not readily detectable. M9 is 86% similar to M1 in its nucleotide sequence and maps next to it on YAC clones. M9 is only 64% similar to M10 and 60% to H2-K k. Probes from M10 define a new subfamily of eight class I genes in C3H mice; five cluster directly distal to H2-T1, and three are located between M9-1-7-8 and M6-4-5 in the H2-M region.
authors.affiliation: Laboratory of Genetics and Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.
authors.forename: S R
authors.initials: SR
authors.lastname: Arepalli
authors.forename: E P
authors.initials: EP
authors.lastname: Jones
authors.forename: T K
authors.initials: TK
authors.lastname: Howcroft
authors.forename: I
authors.initials: I
authors.lastname: Carlo
authors.forename: C
authors.initials: C
authors.lastname: Wang
authors.forename: K F
authors.initials: KF
authors.lastname: Lindahl
authors.forename: D S
authors.initials: DS
authors.lastname: Singer
authors.forename: S
authors.initials: S
authors.lastname: Rudikoff
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002874:Chromosome Mapping; D018076:DNA, Complementary; D006183:H-2 Antigens / Q000235:genetics*; D051379:Mice; D008807:Mice, Inbred BALB C; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid
chemical_list: D018076:DNA, Complementary; D006183:H-2 Antigens