title: [Transitory relaxation of the esophageal inferior sphincter and gastroesophageal reflux].
abstract: Transient lower esophageal sphincter relaxation is the most common cause of reflux disease. These are non-swallow-induced, spontaneous relaxations of the LES, leading to frequent episodes of gastroesophageal reflux. It is still unknown why patients with reflux disease have more TLESRs but the answer may lie in the afferent sensory mechanisms of the stomach, involved in a vagal reflex arc that control the LES.
authors.affiliation: Hôpital cantonal universitaire de Genève, Département de médecine.
authors.forename: B
authors.initials: B
authors.lastname: Armenian
mesh_terms: D000344:Afferent Pathways; D005764:Gastroesophageal Reflux / Q000209:etiology* / Q000503:physiopathology* / Q000628:therapy; D006801:Humans; D011708:Pylorus / Q000503:physiopathology; D013270:Stomach / Q000294:innervation; D014630:Vagus Nerve / Q000503:physiopathology