title: Fibrolamellar hepatocellular carcinoma: results of partial liver resection.
abstract: OBJECTIVE
  To assess the results of partial hepatic resection in the treatment of fibrolamellar hepatocellular carcinoma.
  
  
  RESULTS
  We present six cases of Fibrolamellar hepatocellular carcinoma treated by partial hepatic resection. There were five females and one male with a mean age of 20 (2.6) yr. Five patients were stage IVA and 1 IVB based on the Union International Against Cancer Classification. Two patients, due to recurrent disease, needed further pulmonary resection and a hilar lymphadenectomy. All six cases underwent major resection, three with vascular reconstruction. No operative mortality was recorded; half of the patients displayed some degree of morbidity. One patient died six months after the operation and the rest are alive at 78, 41, 24, 12 and 9 months. We believe that even in advanced cases, an aggressive surgical policy even with vascular reconstruction is justified in patients with fibrolamellar hepatocellular carcinoma.
authors.affiliation: Department of Surgery, Royal Postgraduate Medical School, Hammersmith Hospital, London.
authors.forename: A
authors.initials: A
authors.lastname: Martínez Isla
authors.forename: A
authors.initials: A
authors.lastname: Ferrara
authors.forename: J M
authors.initials: JM
authors.lastname: Badia
authors.forename: I
authors.initials: I
authors.lastname: Holloway
authors.forename: H
authors.initials: H
authors.lastname: Tanaka
authors.forename: A
authors.initials: A
authors.lastname: Riaz
authors.forename: N A
authors.initials: NA
authors.lastname: Habib
mesh_terms: D000293:Adolescent; D000328:Adult; D006528:Carcinoma, Hepatocellular / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000453:epidemiology; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000453:epidemiology