Induction of bioactivity of a non-bioactive glass-ceramic by a chemical treatment.
Glass-ceramic A-W(Al), which was prepared by heat treatment of a MgO-CaO-SiO2-P2O5-Al2O3 glass to precipitate crystalline apatite and wollastonite, shows a higher mechanical strength than glass-ceramic A-W, which was prepared by heat treatment of a MgO-CaO-SiO2-P2O5 glass to precipitate the same types of crystalline phases. The former, however, does not show bone-bonding ability, i.e. bioactivity, whereas the latter shows it. In the present study, in order to induce bioactivity of glass-ceramic A-W(Al), it was treated with HCl or NaOH solutions with different concentrations, and its bioactivity was evaluated by examining the apatite formation on its surface in a simulated body fluid (SBF) with ion concentrations nearly equal to those of human blood plasma. When the glass-ceramic A-W(Al) was pretreated with HCl aqueous solutions with concentrations over 0.1 M, it formed the bone-like apatite on its surface in SBF. This was attributed to the formation of a hydrated silica on its surface by the HCl treatment.
Cho
S B
SB
Department of Material Chemistry, Faculty of Engineering, Kyoto University, Japan.
Miyaji
F
F
Kokubo
T
T
Nakamura
T
T
D001031:Apatites / Q000737:chemistry; D001672:Biocompatible Materials / Q000737:chemistry*; D001826:Body Fluids; D002516:Ceramics / Q000737:chemistry*; D005898:Glass / Q000737:chemistry*; D006801:Humans; D008855:Microscopy, Electron, Scanning; D012996:Solutions; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
D001031:Apatites; D001672:Biocompatible Materials; D012996:Solutions