title: Double-phase Tc-99m-SestaMIBI SPECT imaging in a case of glomus jugulare tumor.
abstract: We performed a double-phase Tc-99m-SestaMIBI SPECT study on a patient who presented with a mass located at the skull base. The results were compared with double-phase T1-201 SPECT study. Early phase (30 min) SPECT images of both radiopharmaceuticals demonstrated increased radiotracer uptake in the region of the tumor. However, late images (180 min) revealed rapid wash-out of Tc-99m-SestaMIBI from the tumor, suggestive of a benign vascular tumor, while T1-201 images showed slower wash-out. Tc-99m-SestaMIBI SPECT findings were also confirmed by carotid angiography and biopsy, while a contemporaneous MRI scan was inconclusive in differentiating benign from malignant tumor. Initial and one-year follow-up whole body CT scans were negative for any metastatic sites, supporting the diagnosis of benign glomus jugulare tumor.
authors.affiliation: Department of Nuclear Medicine, Hacettepe University Medical Faculty, Ankara, Turkey.
authors.forename: L
authors.initials: L
authors.lastname: Kostakoglu
authors.forename: N
authors.initials: N
authors.lastname: Elahi
authors.forename: D
authors.initials: D
authors.lastname: Uzal
authors.forename: B
authors.initials: B
authors.lastname: Khademi
authors.forename: L
authors.initials: L
authors.lastname: Atahan
authors.forename: C F
authors.initials: CF
authors.lastname: Bekdik
mesh_terms: D000792:Angiography; D001706:Biopsy; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D005260:Female; D005500:Follow-Up Studies; D005925:Glomus Jugulare Tumor / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010235:Paraganglioma / Q000000981:diagnostic imaging* / Q000473:pathology; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi