[Values of amyloid protein A in serum of patients after thoracic surgery--preliminary report].
Initial results are presented on the usefulness of evaluating serum amyloid protein A (SAA) contents in patients operated for bronchial cancer. In the group of 20 analysed cases, blood was taken 1 day before and 1, 3, 7, 10 and 14 days after the surgical intervention, and in complicated cases-21 and 30 days after surgery. Erythrocyte sedimentation, leucocyte level, serum amyloid protein A content were measured. The extent of the intervention, the progression of the neoplastic process, clinical and radiological data were analysed. The control group consisted of 10 healthy volunteers. Amyloid protein A was evaluated by ELISA. Statistical analysis was performed on results obtained in 3 groups of patients, divided based on the extent of pulmonary resection. In all patients a statistically significant increase in SAA content was observed on the day preceding the surgery as well as 1, 3, 7 and 10 days after the surgery, in comparison with the control group. SAA level increase, in comparison with the preoperative examination, was statistically significant 1 and 3 days postoperatively in patients after pulmonectomy and only 3 days postoperatively after lobectomy. The lack of statistically significant differences in group 3 (after thoracotomy) resulted from very high preoperative values associated with the advanced progression of the neoplastic process.
Sawa
A
A
Katedry i Kliniki Chirurgii Klatki Piersiowej i Serca Akademii Medycznej w Lublinie.
Iłzecki
M
M
Goździuk
K
K
D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000097:blood*; D001984:Bronchial Neoplasms / Q000097:blood* / Q000601:surgery*; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D008875:Middle Aged; D011184:Postoperative Period; D000685:Serum Amyloid A Protein / Q000032:analysis*; D019616:Thoracic Surgical Procedures
D014408:Biomarkers, Tumor; D000685:Serum Amyloid A Protein