title: Parkinson's disease.
abstract: Parkinson's disease (PD) is one of the most common neurodegenerative diseases and affects 150 to 200 people per 100,000 population. Rapid advances have been made in the neurobiology of PD; this disorder is now recognized as a model of dysfunction in fronto-striatal circuits expressed by motor and behavioral symptoms. Several clinical and surgical strategies for the management of PD are discussed.
authors.affiliation: Department of Neurology, Hospital das Clínicas, University of São Paulo Medical School, Brazil.
authors.forename: E R
authors.initials: ER
authors.lastname: Barbosa
authors.forename: J C
authors.initials: JC
authors.lastname: Limongi
authors.forename: J L
authors.initials: JL
authors.lastname: Cummings
mesh_terms: D000978:Antiparkinson Agents / Q000627:therapeutic use; D001526:Behavioral Symptoms / Q000503:physiopathology / Q000628:therapy; D001921:Brain / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D009410:Nerve Degeneration / Q000209:etiology / Q000503:physiopathology; D009434:Neural Pathways / Q000503:physiopathology; D010300:Parkinson Disease / Q000175:diagnosis / Q000209:etiology / Q000473:pathology / Q000628:therapy
chemical_list: D000978:Antiparkinson Agents