title: Bis-quinolinium cyclophanes: 6,10-diaza-3(1,3),8(1,4)-dibenzena-1,5(1,4)- diquinolinacyclodecaphane (UCL 1684), the first nanomolar, non-peptidic blocker of the apamin-sensitive Ca(2+)-activated K+ channel.
authors.affiliation: Department of Chemistry and Pharmacology, University College London, U.K.
authors.forename: J C
authors.initials: JC
authors.lastname: Rosa
authors.forename: D
authors.initials: D
authors.lastname: Galanakis
authors.forename: C R
authors.initials: CR
authors.lastname: Ganellin
authors.forename: P M
authors.initials: PM
authors.lastname: Dunn
authors.forename: D H
authors.initials: DH
authors.lastname: Jenkinson
mesh_terms: D000473:Alkanes / Q000737:chemistry* / Q000494:pharmacology; D000818:Animals; D001030:Apamin / Q000494:pharmacology*; D001921:Brain / Q000502:physiology; D006801:Humans; D015394:Molecular Structure; D009865:Oocytes / Q000187:drug effects / Q000502:physiology; D026902:Potassium Channel Blockers; D015221:Potassium Channels; D024681:Potassium Channels, Calcium-Activated; D011806:Quinolinium Compounds / Q000737:chemistry* / Q000494:pharmacology; D051381:Rats; D051640:Small-Conductance Calcium-Activated Potassium Channels; D013329:Structure-Activity Relationship; D014982:Xenopus laevis
chemical_list: C110349:6,10-diaza-3(1,3),8(1,4)dibenzena-1,5(1,4)diquinolinacyclodecaphane; D000473:Alkanes; D026902:Potassium Channel Blockers; D015221:Potassium Channels; D024681:Potassium Channels, Calcium-Activated; D011806:Quinolinium Compounds; D051640:Small-Conductance Calcium-Activated Potassium Channels; D001030:Apamin