Interpretation and estimation of relative potency in vaccines.
The implication of relative potency varies between categories of assays. This review clarifies the meaning of the relative potency concept in each of several classes of assays commonly used to evaluate vaccines, so that an appropriate analytical procedure may be selected. Methods of estimating relative potency are reviewed and illustrated.
Siev
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Center for Veterinary Biologics, United States Department of Agriculture, Ames, IA 50010, USA. dsiev@aphis.usda.gov
D000818:Animals; D006801:Humans; D007118:Immunoassay; D014612:Vaccines / Q000494:pharmacology*
D014612:Vaccines