title: [Development of new generation of vaccines based on structural conjugation of antigens and synthetic polymer immunomodulators].
abstract: The immunogenetic principle of creation of artificial antigens and vaccines possessing the abnormal immunogenecity and having capability to induce the high immune response in weakly reacting individuals have been suggested and proved by experiment. The vaccines of a new generation against the grippe pathogene, salmonellosis have been developed on the basis of this principle. In theory the methods of receiving allergovaccines for allergy disease therapy have been worked out and based.
authors.forename: R M
authors.initials: RM
authors.lastname: Khaitov
mesh_terms: D000276:Adjuvants, Immunologic / Q000737:chemistry / Q000627:therapeutic use; D000485:Allergens / Q000737:chemistry / Q000276:immunology; D000818:Animals; D000941:Antigens / Q000737:chemistry / Q000276:immunology*; D000942:Antigens, Bacterial / Q000737:chemistry / Q000276:immunology; D000956:Antigens, Viral / Q000737:chemistry / Q000276:immunology; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D011058:Pollen / Q000276:immunology; D011108:Polymers / Q000737:chemistry; D014614:Vaccines, Synthetic / Q000627:therapeutic use
chemical_list: D000276:Adjuvants, Immunologic; D000485:Allergens; D000941:Antigens; D000942:Antigens, Bacterial; D000956:Antigens, Viral; D011108:Polymers; D014614:Vaccines, Synthetic