Toxicity and complications of inhaled nitric oxide.
The extent of toxicity and adverse effects resulting from inhaled NO is poorly understood. Presumably, toxicity is low and adverse effects are rare at the doses commonly used to treat acute respiratory failure. Much remains to be learned about this important topic, however.
Hess
D
D
Department of Respiratory Care, Massachusetts General Hospital, Boston, USA.
Bigatello
L
L
Hurford
W E
WE
D000280:Administration, Inhalation; D001792:Blood Platelets / Q000187:drug effects; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology; D000860:Hypoxia / Q000209:etiology; D008708:Methemoglobinemia / Q000139:chemically induced; D009569:Nitric Oxide / Q000009:adverse effects* / Q000633:toxicity*; D009585:Nitrogen Dioxide / Q000378:metabolism; D012131:Respiratory Insufficiency / Q000188:drug therapy
D009569:Nitric Oxide; D009585:Nitrogen Dioxide