title: Lymphocytic thyroiditis in beagle dogs in a breeding colony: findings of serum autoantibodies.
abstract: Three serum autoantibodies against antigens of the thyroid gland were detected by the indirect immunofluorescence in a Beagle dog breeding colony. The anti-thyroglobulin autoantibody was present in 10.0%, the anti-microsomal antigen autoantibody was present in 24.6%, and the anti-nuclear substance autoantibody in 10.8% of examined sera, respectively. Only the presence of anti-thyroglobulin autoantibodies could be correlated with histologic findings of the lymphocytic thyroiditis in the same colony.
authors.affiliation: Institute of Histology and Embryology, 2nd Faculty of Medicine, Charles University, Praha, Czech Republic. Ludek.Vajner@lfmotol.cuni.cz
authors.forename: L
authors.initials: L
authors.lastname: Vajner
mesh_terms: D000818:Animals; D001323:Autoantibodies / Q000032:analysis*; D004283:Dog Diseases / Q000235:genetics* / Q000276:immunology; D004285:Dogs; D005260:Female; D008297:Male; D013967:Thyroiditis, Autoimmune / Q000235:genetics / Q000276:immunology / Q000662:veterinary*
chemical_list: D001323:Autoantibodies