title: Nitrite- and chloride-selective fluorescent nano-optodes and in vitro application to rat conceptuses.
abstract: Nitrite- and chloride-selective, ion correlation-based, nano-optodes have been prepared for application in vitro. These fluorescent, liquid polymer based sensors have theoretically predictable responses to anion activities and good selectivity. The nitrite sensor, prepared with a vitamin B12 derivative ionophore, would be useful for determination of oxidized nitric oxide. Chloride nano-optodes, as well as micro-optodes, prepared with an indium porphyrin ionophore, were utilized to determine chloride levels both on the surface and inside the visceral yolk sac of organogenesis-stage rat conceptuses.
authors.affiliation: Department of Chemistry, University of Michigan, Ann Arbor 48109-1055, USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Barker
authors.forename: B A
authors.initials: BA
authors.lastname: Thorsrud
authors.forename: R
authors.initials: R
authors.lastname: Kopelman
mesh_terms: D000818:Animals; D002712:Chlorides / Q000032:analysis*; D004622:Embryo, Mammalian / Q000737:chemistry*; D005260:Female; D005336:Fiber Optic Technology; D005456:Fluorescent Dyes / Q000737:chemistry*; D008839:Microelectrodes; D009573:Nitrites / Q000032:analysis*; D011247:Pregnancy; D051381:Rats
chemical_list: D002712:Chlorides; D005456:Fluorescent Dyes; D009573:Nitrites