[Retiform hemangioendothelioma. Clinico-pathologic case report and discussion of the group of low malignancy vascular tumors].
We report a locally recurrent retiform haemangioendothelioma (RHE) on the right great toe in a 40-year-old woman. There was a secondary soft tissue lesion on her right lower leg. Histologically, primary lesion, local recurrence and the secondary soft tissue lesion (soft tissue metastasis?) showed identical features. Long, arborizing, neoplastic blood vessels were lined by CD31 and factor VIII-positive, monomorphic endothelial tumour cells; focally solid tumour areas, papillae and a prominent inflammatory infiltrate consisting of mature B and T lymphocytes were noted. The concept and the group of low-grade malignant vascular neoplasms is discussed, with special emphasis on inclusion of RHE in this category.
Mentzel
T
T
Institut für Pathologie der Friedrich-Schiller-Universität Jena.
Stengel
B
B
Katenkamp
D
D
D000328:Adult; D001402:B-Lymphocytes / Q000473:pathology; D014408:Biomarkers, Tumor / Q000032:analysis; D004730:Endothelium, Vascular / Q000473:pathology; D005169:Factor VIII / Q000032:analysis; D005260:Female; D006390:Hemangioendothelioma / Q000098:blood supply / Q000473:pathology*; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000098:blood supply / Q000473:pathology*; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000032:analysis; D012983:Soft Tissue Neoplasms / Q000098:blood supply / Q000473:pathology*; D013601:T-Lymphocytes / Q000473:pathology; D014034:Toes / Q000098:blood supply / Q000473:pathology
D014408:Biomarkers, Tumor; D019408:Platelet Endothelial Cell Adhesion Molecule-1; D005169:Factor VIII