The bioavailability of ginkgolides in Ginkgo biloba extracts.
A new Ginkgo biloba leaf extract, BioGinkgo 27/7, was prepared using a method that enriches ginkgolide B. The bioavailability of ginkgolides in these extracts was assessed in rabbits in comparison with a commercially available standardized 24/6 extract. It was found that, after a single dose, a higher concentration of ginkgolides was maintained for a longer period of time with these extracts than was found with commercial extract prepared by existing methods.
Li
C L
CL
School of Pharmacy, Beijing Medical University, People's Republic of China.
Wong
Y Y
YY
D000818:Animals; D001682:Biological Availability; D001792:Blood Platelets / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism; D004224:Diterpenes; D005260:Female; D046934:Ginkgolides; D007783:Lactones / Q000493:pharmacokinetics*; D008297:Male; D010936:Plant Extracts / Q000737:chemistry*; D010972:Platelet Activating Factor / Q000037:antagonists & inhibitors; D011817:Rabbits
D004224:Diterpenes; D046934:Ginkgolides; D007783:Lactones; D010936:Plant Extracts; D010972:Platelet Activating Factor; C045856:ginkgolide B