title: Quantitative cerebral perfusion SPECT in systemic lupus erythematosus with severe central nervous involvement--before and after methylprednisolone pulse therapy.
abstract: Severe cerebral involvement may occur in patients with systemic lupus erythematosus. Methylprednisolone pulse therapy is a management choice for those with severe cerebral involvement. However, its effectiveness is uncertain. This article describes Tc-99m HMPAO cerebral perfusion single-photon emission computerized tomography to document the restoration of cerebral perfusion after methylprednisolone pulse therapy in a case of systemic lupus erythromatosus with severe cerebral manifestations.
authors.affiliation: Department of Nuclear Medicine, Sun Yat-Sen Hospital Taiwan, Republic of China.
authors.forename: D L
authors.initials: DL
authors.lastname: You
authors.forename: K Y
authors.initials: KY
authors.lastname: Tzen
authors.forename: P F
authors.initials: PF
authors.lastname: Kao
authors.forename: M F
authors.initials: MF
authors.lastname: Tsai
mesh_terms: D000293:Adolescent; D002493:Central Nervous System Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation / Q000187:drug effects; D005260:Female; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000188:drug therapy; D008775:Methylprednisolone / Q000008:administration & dosage*; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D005938:Glucocorticoids; D008775:Methylprednisolone