title: Fat-suppressed MRI of musculoskeletal infection: fast T2-weighted techniques versus gadolinium-enhanced T1-weighted images.
abstract: OBJECTIVE
  To investigate gadolinium's role in imaging musculoskeletal infection by comparing the conspicuity and extent of inflammatory changes demonstrated on gadolinium-enhanced fat-suppressed T1-weighted images versus fat-suppressed fast T2-weighted sequences.
  
  
  METHODS
  Eighteen patients with infection were imaged in a 1.5-T unit, using frequency-selective and/or inversion recovery fat-suppressed fast T2-weighted images (T2WI) and gadolinium-enhanced frequency-selective fat-suppressed T1-weighted images (T1WI). Thirty-four imaging planes with both a fat-suppressed gadolinium-enhanced T1-weighted sequence and a fat-suppressed T2-weighted sequence were obtained. Comparison of the extent and conspicuity of signal intensity changes was made for both bone and soft tissue in each plane.
  
  
  RESULTS
  In bone, inflammatory change was equal in extent and conspicuity on fat-suppressed T2WI and fat-suppressed T1WI with gadolinium in 19 planes, more extensive or conspicuous on T2WI in three planes, and less so on T2WI in two planes. Marrow was normal on all three sequences in 10 cases. In soft tissue, inflammatory change was seen equally well in 20 instances, more extensively or conspicuously on the T2WI in 11 instances, and less so on T2WI in 2 instances. One case had no soft tissue involvement on any of the sequences. Five abscesses and three joint effusions were present, all more conspicuously delineated from surrounding inflammatory change on the fat-saturated T1WI with gadolinium. The average imaging time for the fat-saturated T1WI with gadolinium was 6.75 min, while that of the T2-weighted sequences was 5.75 min.
  
  
  CONCLUSIONS
  Routine use of gadolinium is not warranted. Instead, gadolinium should be reserved for clinically suspected infection in or around a joint, and in cases refractory to medical or surgical treatment due to possible abscess formation.
authors.affiliation: Department of Radiology, North Shore University Hospital, Manhasset, NY 11030, USA.
authors.forename: T T
authors.initials: TT
authors.lastname: Miller
authors.forename: D A
authors.initials: DA
authors.lastname: Randolph
authors.forename: R B
authors.initials: RB
authors.lastname: Staron
authors.forename: F
authors.initials: F
authors.lastname: Feldman
authors.forename: S
authors.initials: S
authors.lastname: Cushin
mesh_terms: D000273:Adipose Tissue / Q000033:anatomy & histology*; D000328:Adult; D000368:Aged; D001424:Bacterial Infections / Q000175:diagnosis*; D001850:Bone Diseases, Infectious / Q000175:diagnosis; D005682:Gadolinium / Q000494:pharmacology*; D006801:Humans; D007249:Inflammation / Q000175:diagnosis; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D009140:Musculoskeletal Diseases / Q000175:diagnosis*; D011446:Prospective Studies; D018461:Soft Tissue Infections / Q000175:diagnosis
chemical_list: D005682:Gadolinium