Effect of an ointment containing boric acid, zinc oxide, starch and petrolatum on psoriasis.
A randomized double-blind controlled trial was undertaken to study the efficacy of a cow udder ointment versus petroalatum alone. A total of 30 patients participated in the study. Sixteen patients completed the trial with 8 of 9 patients improving in the active group and 6 of 7 patients improving in the placebo group. This difference was not statistically significant. The use of a cow udder ointment for psoriasis cannot be supported, particularly with the potential for side effects.
Limaye
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S
Department of Dermatology, Queen Elizabeth Hospital, Adelaide, Australia.
Weightman
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W
D000287:Administration, Topical; D000328:Adult; D000368:Aged; D001888:Boric Acids / Q000008:administration & dosage*; D004311:Double-Blind Method; D004338:Drug Combinations; D004643:Emollients / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009824:Ointments / Q000627:therapeutic use; D010577:Petrolatum / Q000008:administration & dosage*; D011565:Psoriasis / Q000188:drug therapy*; D013213:Starch / Q000008:administration & dosage; D016896:Treatment Outcome; D015034:Zinc Oxide / Q000008:administration & dosage*
D001888:Boric Acids; D004338:Drug Combinations; D004643:Emollients; D009824:Ointments; D010577:Petrolatum; D013213:Starch; C032688:boric acid; D015034:Zinc Oxide