title: Conjunctival metastasis as the initial manifestation of lung cancer.
abstract: OBJECTIVE
  To report a case of conjunctival metastasis as the initial manifestation of lung cancer.
  
  
  METHODS
  A 55-year-old man without known systemic disease developed a conjunctival mass in his right eye. He underwent excision of the tumor and systemic evaluation.
  
  
  RESULTS
  Histopathologically, the mass was a metastatic squamous cell carcinoma. Further evaluation disclosed a primary bronchogenic carcinoma with metastasis to ribs and brain. The primary and secondary tumors were treated with chemotherapy and irradiation.
  
  
  CONCLUSIONS
  Conjunctival metastasis may be the initial manifestation of lung cancer. It should be considered in the differential diagnosis of a deep conjunctival mass.
authors.affiliation: Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA 19107, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Shields
authors.forename: K
authors.initials: K
authors.lastname: Gündüz
authors.forename: C L
authors.initials: CL
authors.lastname: Shields
authors.forename: R C
authors.initials: RC
authors.lastname: Eagle
authors.forename: P
authors.initials: P
authors.lastname: DePotter
authors.forename: E
authors.initials: E
authors.lastname: van Rens
mesh_terms: D001932:Brain Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary; D002283:Carcinoma, Bronchogenic / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D017024:Chemotherapy, Adjuvant; D003230:Conjunctival Neoplasms / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D003937:Diagnosis, Differential; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D008297:Male; D008875:Middle Aged; D018714:Radiotherapy, Adjuvant; D013899:Thoracic Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000556:secondary