title: Digital radiology using active matrix readout of amorphous selenium: theoretical analysis of detective quantum efficiency.
abstract: A flat-panel x-ray imaging detector using a layer of amorphous selenium (a-Se) for direct conversion of x rays (to charge) and an active matrix for self-scanned readout is being investigated for digital radiology. A theoretical analysis of the spatial frequency dependent detective quantum efficiency (DQE(f)) of the self-scanned a-Se detector is performed based on a model of signal and noise propagation in a cascaded imaging system. Because of the high intrinsic resolution of a-Se and the pixelated active matrix readout method, such detectors are inherently undersampled and aliasing is present. The presampling modulation transfer function (MTF) and aliased noise power spectrum (NPS) of the detector were used in the analysis of DQE(f). It is proven that the aliased NPS for the self-scanned a-Se detectors is white. Since the shape of DQE(f) is determined by the ratio of MTF squared and the NPS, the shape of DQE(f) follows the square of the presampling MTF of the detector as a result of the white NPS. The analysis also shows that DQE(0) is proportional to the pixel fill factor, i.e., the fraction of each pixel area used for image charge collection. The DQE analysis is applied to detector parameters for three x-ray imaging applications: mammography, chest radiography, and fluoroscopy. The effects of pixel fill factor, imaging geometry (i.e., incident angle of x rays), and various sources of electronic noise on the detector DQE(f) are discussed. Strategies for maximizing detector DQE for each x-ray imaging application are proposed.
authors.affiliation: Department of Medical Biophysics, University of Toronto, Sunnybrook Health Science Centre, Ontario, Canada. zhao@srcl.sunnybrook.utoronto.ca
authors.forename: W
authors.initials: W
authors.lastname: Zhao
authors.forename: J A
authors.initials: JA
authors.lastname: Rowlands
mesh_terms: D008962:Models, Theoretical; D011789:Quantum Theory; D011857:Radiographic Image Interpretation, Computer-Assisted; D012643:Selenium; D014965:X-Rays
chemical_list: D012643:Selenium