title: Reference intervals for serum thyrotropin, free thyroxine and free triiodothyronine in healthy adults in Finland, measured by an immunoautomate based on time-resolved fluorescence (AutoDELFIA).
abstract: We have established reference intervals for healthy adults of serum thyrotropin, free thyroxine and free triiodothyronine using the AutoDELFIA (Wallac, Finland) automatic measuring device. The determination of reference intervals in a proper manner is costly, and many laboratories adopt reference ranges from the literature rather than determining them alone. This is the first report on reference values in thyroidology where this automatic system based on time-resolved fluorescence has been used. The reference intervals for thyrotropin, free thyroxine and free triiodothyronine were 0.6-4.3 mIU/l, 9.6-17.1 pmol/l and 4.3-7.5 pmol/l, respectively.
authors.affiliation: Department of Clinical Chemistry, University Central Hospital of Turku, Finland. eeva.taimela@bts.redcross.fi
authors.forename: E
authors.initials: E
authors.lastname: Taimela
authors.forename: V
authors.initials: V
authors.lastname: Kairisto
authors.forename: P
authors.initials: P
authors.lastname: Koskinen
authors.forename: A
authors.initials: A
authors.lastname: Leino
authors.forename: K
authors.initials: K
authors.lastname: Irjala
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005453:Fluorescence; D006801:Humans; D008297:Male; D008875:Middle Aged; D011933:Reagent Kits, Diagnostic; D012016:Reference Values; D013972:Thyrotropin / Q000097:blood*; D013974:Thyroxine / Q000097:blood*; D014284:Triiodothyronine / Q000097:blood*
chemical_list: D011933:Reagent Kits, Diagnostic; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine