[Role of free radicals in articular inflammatory process].
The authors review recent studies supporting the role of free radicals in the inflammatory articular process. More specifically, superoxide anion and its derived active species and nitric oxide are analyzed regarding their generation by the articular cells and tissues, their destructive activity n these specialized tissues. Likewise, effects of the inhibition of free radicals production or activity in the inflammatory process is also commented.
Laurindo
I M
IM
Disciplina de Reumatologia, Faculdade de Medicina, Universidade de São Paulo.
de Mello
S B
SB
Novaes
G dos S
Gdos S
Palacios
F A
FA
Yoshinari
N H
NH
D005609:Free Radicals / Q000378:metabolism; D006801:Humans; D009569:Nitric Oxide / Q000378:metabolism*; D012216:Rheumatic Diseases / Q000378:metabolism*; D013481:Superoxides / Q000378:metabolism*
D005609:Free Radicals; D013481:Superoxides; D009569:Nitric Oxide