Anticomplementary activity of ginseng saponins and their degradation products.
The anticomplementary activity of ginseng saponins and their degradation products obtained by chemical treatment of Korean red ginseng saponins was investigated. The total saponin and its major components showed strong anticomplementary activity and their structure-activity relationship was evaluated.
Kim
D S
DS
Korea Research Institute of Bioscience and Biotechnology, Taejon, Korea.
Oh
S R
SR
Lee
I S
IS
Jung
K Y
KY
Park
J D
JD
Kim
S I
SI
Lee
H K
HK
D003169:Complement Inactivator Proteins / Q000302:isolation & purification / Q000494:pharmacology*; D003171:Complement Pathway, Classical / Q000187:drug effects*; D006801:Humans; D007723:Korea; D005894:Panax; D010946:Plants, Medicinal; D012502:Sapogenins / Q000302:isolation & purification / Q000494:pharmacology*; D012503:Saponins / Q000302:isolation & purification / Q000494:pharmacology*; D013329:Structure-Activity Relationship
D003169:Complement Inactivator Proteins; D012502:Sapogenins; D012503:Saponins