title: Pulmonary high-resolution computed tomography versus gallium scintigraphy: diagnostic utility in the diagnosis of patients with AIDS who have chest symptoms and normal or equivocal chest radiographs.
abstract: Fifty-six consecutive symptomatic patients with AIDS referred for gallium scintigraphy were prospectively studied with chest high-resolution computed tomography (HRCT). Results of gallium and HRCT were correlated with findings of bronchoscopy or clinical follow-up for 1 month from time of discharge. Twenty-two patients were eventually diagnosed with at least one of the following: Pneumocystis carinii, cytomegalovirus, Mycobacterium avium complex, bacteria, Kaposi's sarcoma, or lymphocytic interstitial pneumonitis. HRCT was more sensitive (82%) and more specific (91%) than gallium (59% and 75%, respectively). HRCT yielded higher positive predictive values (86%) and negative predictive values (88%) than did gallium (62% and 73%, respectively). HRCT was more helpful in guiding the method of biopsy and directing the brochoscopist to the diseased lung segment that would maximize diagnostic yield.
authors.affiliation: Department of Radiology, Illinois Masonic Medical Center, Chicago 60657, USA.
authors.forename: K J
authors.initials: KJ
authors.lastname: Kirshenbaum
authors.forename: R
authors.initials: R
authors.lastname: Burke
authors.forename: F
authors.initials: F
authors.lastname: Fanapour
authors.forename: K
authors.initials: K
authors.lastname: Lapat
authors.forename: C
authors.initials: C
authors.lastname: Overbeeke
authors.forename: D
authors.initials: D
authors.lastname: Blatt
authors.forename: A
authors.initials: A
authors.lastname: Sukerkar
authors.forename: R P
authors.initials: RP
authors.lastname: Cavallino
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000000981:diagnostic imaging*; D000328:Adult; D005260:Female; D005710:Gallium Radioisotopes; D006801:Humans; D008171:Lung Diseases / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D005710:Gallium Radioisotopes