Incidence of extrapyramidal syndromes in AIDS patients and a comparison group of medically ill inpatients.
The authors retrospectively reviewed the charts of 29 inpatients with AIDS and 24 medically ill inpatients, all of whom were exposed to neuroleptics. Results adjusted for age, gender, type and dosage of neuroleptic, and extrapyramidal prophylaxis indicated that inpatients with AIDS were 7 times more likely to develop extrapyramidal syndromes (EPS) from neuroleptics than the comparison group of medically ill inpatients. Possible neuroanatomic, neuropathologic, and neurochemical reasons for the vulnerability of patients with AIDS to EPS are reviewed.
Ramachandran
G
G
Department of Psychiatry, State University of New York Health Science Center at Brooklyn, USA.
Glickman
L
L
Levenson
J
J
Rao
C
C
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D001480:Basal Ganglia Diseases / Q000139:chemically induced* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
D014150:Antipsychotic Agents