[Biological activity of the protein-polysaccharide complex secreted by Bifidobacterium adolescentis].
Extracellular protein-polysaccharide complex (PPC) of Bifidobacterium adolescentis stimulated growth, acidogenesis, accumulation of extracellular proteins and enzymes and the utilization of sugars in both physiologically active and anabiotic forms of B. adolescentis cultivated in rich nutrient media. The PPC variants III-DN-48 and IV-DN-24 isolated from the cell surface of B. adolescentis had the most pronounced bifidogenic effect. PPC promoted a quick and complete rehabitation of anabiotic bifidobacteria. The PPC variants III-DN-48 and IV-DN-24 were shown to be nontoxic for the population of Tetrahymena pyriformis W. Nor were they mutagenic or sensitizing. At the same time, PPCs showed pronounced adaptogenic and growth-promoting activities.
Novik
G I
GI
Astapovich
N I
NI
Riabaia
N E
NE
Bogdan
A S
AS
D000818:Animals; D001426:Bacterial Proteins / Q000378:metabolism / Q000494:pharmacology*; D001644:Bifidobacterium / Q000378:metabolism*; D050260:Carbohydrate Metabolism; D002455:Cell Division / Q000187:drug effects; D003470:Culture Media; D006863:Hydrogen-Ion Concentration; D009153:Mutagens / Q000494:pharmacology; D011134:Polysaccharides / Q000378:metabolism / Q000494:pharmacology*; D013769:Tetrahymena pyriformis / Q000187:drug effects
D001426:Bacterial Proteins; D003470:Culture Media; D009153:Mutagens; D011134:Polysaccharides