Organization of DNA sequences near the centromere of the Drosophila melanogaster Y chromosome.
The structural analysis of a yeast artificial chromosome clone from Drosophila melanogaster enriched in dodecasatellite sequences has led us to find a new retrotransposon that we have called Circe. Moreover, this retrotransposon has allowed the isolation of a contig encompassing approximately 200 kb near the centromere of the Y chromosome, providing an entry point into a region from which very little sequence information has been obtained to date. The molecular characterization of the contig has shown the presence of HeT-A telomeric retrotransposons close to the centromere of the Y chromosome, suggesting a telocentric origin for this submetacentric chromosome.
Losada
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Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM), E-28049 Madrid, Spain.
Abad
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JP
Villasante
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D000818:Animals; D001483:Base Sequence; D002503:Centromere / Q000737:chemistry / Q000235:genetics*; D002874:Chromosome Mapping; D018244:Chromosomes, Artificial, Yeast / Q000737:chemistry / Q000235:genetics; D004247:DNA / Q000032:analysis* / Q000235:genetics*; D004251:DNA Transposable Elements; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000235:genetics*; D015683:Gene Products, gag; D019476:Insect Proteins / Q000235:genetics; D008969:Molecular Sequence Data; D018626:Retroelements / Q000235:genetics; D017422:Sequence Analysis, DNA; D014998:Y Chromosome / Q000737:chemistry / Q000235:genetics*
D004251:DNA Transposable Elements; D029721:Drosophila Proteins; D015683:Gene Products, gag; C103996:HeT-A-gag protein, Drosophila; D019476:Insect Proteins; D018626:Retroelements; D004247:DNA