title: False-positive somatostatin receptor scintigraphy due to an accessory spleen.
abstract: A patient with previous left caudal pancreatectomy and splenectomy presented with Zollinger-Ellison syndrome. Abdominal CT and endoscopic ultrasonography revealed a mass in the splenic area. Somatostatin receptor scintigraphy showed a nodular increase of the uptake corresponding to the lesion detected with conventional imaging. A second laparotomy was performed and the mass was resected. Histological analysis showed that the nodular lesion was an accessory spleen. Since physiologic uptake of 111In-pentetreotide is seen in the spleen, an accessory spleen mimicking a tumor, specially after previous splenectomy, may result in false-positive somatostatin receptor scintigraphy.
authors.affiliation: Nuclear Medicine, Department, Bichat Hospital, Paris, France.
authors.forename: R
authors.initials: R
authors.lastname: Lebtahi
authors.forename: G
authors.initials: G
authors.lastname: Cadiot
authors.forename: J P
authors.initials: JP
authors.lastname: Marmuse
authors.forename: C
authors.initials: C
authors.lastname: Vissuzaine
authors.forename: Y
authors.initials: Y
authors.lastname: Petegnief
authors.forename: A
authors.initials: A
authors.lastname: Courillon-Mallet
authors.forename: D
authors.initials: D
authors.lastname: Cattan
authors.forename: M
authors.initials: M
authors.lastname: Mignon
authors.forename: D
authors.initials: D
authors.lastname: Le Guludec
mesh_terms: D005189:False Positive Reactions; D006801:Humans; D007205:Indium Radioisotopes; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D017481:Receptors, Somatostatin / Q000032:analysis*; D013004:Somatostatin / Q000031:analogs & derivatives*; D013154:Spleen / Q000002:abnormalities* / Q000000981:diagnostic imaging; D015043:Zollinger-Ellison Syndrome / Q000000981:diagnostic imaging*
chemical_list: D007205:Indium Radioisotopes; D017481:Receptors, Somatostatin; D013004:Somatostatin; C081788:pentetreotide