title: Cyclosporine: update on pharmacology, analytical techniques and therapeutic monitoring.
abstract: The Authors relate about the current state of knowledge on Cyclosporin A metabolism, mechanism of action, toxic potential, necessity of therapeutic monitoring. The methods for measurement of Cyclosporin A and its metabolites and the study of their immunosuppressive activity are described. Their use for measurement of Cyclosporin G is discussed.
authors.affiliation: Laboratorio di Analisi Cliniche e Microbiologia, Ospedale Civile, Piacenza.
authors.forename: L
authors.initials: L
authors.lastname: Santori
authors.forename: M
authors.initials: M
authors.lastname: Rastelli
authors.forename: B
authors.initials: B
authors.lastname: Arena
authors.forename: M A
authors.initials: MA
authors.lastname: Morleo
mesh_terms: D000818:Animals; D016572:Cyclosporine / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine