title: The effects of a selection of alkaloids on the invertase activity of some higher plants.
abstract: The effects of several alkaloids on the invertase activities of Ricinus communis, Solanum tuberosum, Oryza sativa and Carica papaya were studied. The following alkaloids: caffeine, berberine, strychnine, morphine, ethyl-narceine and nornicotine, have different inhibitory effects on invertase activity. Kinetic studies of the alkaloid inhibition revealed that different alkaloids exhibited diverse types of inhibition of invertase. It was found that alkaloids form reversible complexes with invertases. However cocaine and potato glycoalkaloids were activators of some invertase. The sugar moiety of potato glycoalkaloids were also activators. It is concluded that alkaloids may be effectors of higher plant invertase activity.
authors.affiliation: Cátedra de Fitoquímica, Facultad de Bioquímica, Química y Farmacia, Universidad Nacional de Tucuman.
authors.forename: H P
authors.initials: HP
authors.lastname: Rojo
authors.forename: E N
authors.initials: EN
authors.lastname: Quiroga
authors.forename: M A
authors.initials: MA
authors.lastname: Vattuone
authors.forename: A R
authors.initials: AR
authors.lastname: Sampietro
mesh_terms: D000470:Alkaloids / Q000494:pharmacology*; D006026:Glycoside Hydrolases / Q000037:antagonists & inhibitors*; D010940:Plant Proteins / Q000037:antagonists & inhibitors*; D010944:Plants / Q000187:drug effects / Q000201:enzymology*; D043324:beta-Fructofuranosidase
chemical_list: D000470:Alkaloids; D010940:Plant Proteins; D006026:Glycoside Hydrolases; D043324:beta-Fructofuranosidase