title: Is splenectomy necessary in devascularization procedures for treatment of bleeding portal hypertension?
abstract: OBJECTIVE
  To investigate whether splenectomy as a part of devascularization procedures is necessary.
  
  
  METHODS
  Prospective, controlled, randomized trial.
  
  
  METHODS
  University hospital, referral center.
  
  
  METHODS
  A total of 55 patients (Child-Pugh class A and B) with a history of bleeding portal hypertension were treated by means of a modified Sugiura-Futagawa procedure. Twenty-three patients underwent splenectomy and 22 did not.
  
  
  METHODS
  Postoperative outcome was recorded and comparison of the 2 groups was done with the Fisher exact test. Kaplan-Meier survival curves were constructed. Main outcome and postoperative differences between the patients who underwent splenectomy and those who did not were investigated.
  
  
  RESULTS
  Both groups were comparable in the postoperative period. Significant differences were observed in transfusion requirements and postoperative portal vein thrombosis, both favoring the group without splenectomy. No differences in rebleeding, encephalopathy rate, operative time, or postoperative complications were observed.
  
  
  CONCLUSIONS
  Splenectomy is not routinely necessary in devascularization procedures for bleeding portal hypertension.
authors.affiliation: Portal Hypertension Clinic, Instituto Nacional de la Nutricion, Salvador Zubiran, Mexico City, Mexico.
authors.forename: H
authors.initials: H
authors.lastname: Orozco
authors.forename: M A
authors.initials: MA
authors.lastname: Mercado
authors.forename: R
authors.initials: R
authors.lastname: Martinez
authors.forename: M
authors.initials: M
authors.lastname: Tielve
authors.forename: C
authors.initials: C
authors.lastname: Chan
authors.forename: M
authors.initials: M
authors.lastname: Vasquez
authors.forename: G
authors.initials: G
authors.lastname: Zenteno-Guichard
authors.forename: J P
authors.initials: JP
authors.lastname: Pantoja
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000401:mortality / Q000601:surgery*; D006801:Humans; D006975:Hypertension, Portal / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D011446:Prospective Studies; D013156:Splenectomy; D016019:Survival Analysis; D016896:Treatment Outcome