[Role of genetics in the risk assessment of hypertensive patients].
The identification of genes responsible for the predisposition to hypertension could help define the exact role of genetics in the risk assessment of hypertensive subjects. Large scale genetic epidemiological trials and recent advances in the knowledge of the human genome should resolve this problem in the years to come. In addition to the role of each gene, the interaction between genes and the environment will have to be defined in the context of the physiopathology of this condition. The identification of genes which may favourise the complications of hypertension is an objective as important for definition of risks as for the management of the disease.
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INSERM U358, hôpital Saint-Louis, Paris.
D000818:Animals; D004195:Disease Models, Animal; D004198:Disease Susceptibility; D030342:Genetic Diseases, Inborn / Q000235:genetics; D005819:Genetic Markers; D005821:Genetic Techniques; D005838:Genotype; D006801:Humans; D006973:Hypertension / Q000235:genetics* / Q000503:physiopathology; D051381:Rats; D012307:Risk Factors
D005819:Genetic Markers