title: HIV vaccine acceptance among heterosexual clients of a sexually transmitted diseases clinic.
abstract: We evaluated the willingness of clients at a large urban sexually transmitted diseases (STD) clinic in the southeastern United States to participate in future trials of preventive vaccines for HIV type 1 (HIV-1). A single trained interviewer administered an oral survey instrument to STD clinic clients over a 4-week enrollment period. The participants were 167 randomly selected clients (90 men and 77 women), most of whom were young, African-American heterosexuals. Risk behaviors for HIV-1 infection were highly prevalent. Overall, 67% of clients expressed willingness to consider participation in an HIV-1 vaccine trial. By univariate analysis, prior HIV-1 testing was significantly associated with willingness to participate (P = 0.04). Multivariate analysis revealed that female gender (P = 0.05) and prior HIV-1 testing (P = 0.03) were significant predictors of willingness to participate.
authors.affiliation: University of Alabama at Birmingham, 35294-2170, USA.
authors.forename: J
authors.initials: J
authors.lastname: Tello
authors.forename: S J
authors.initials: SJ
authors.lastname: Soong
authors.forename: B
authors.initials: B
authors.lastname: Hunter
authors.forename: R
authors.initials: R
authors.lastname: Meriwether
authors.forename: E W
authors.initials: EW
authors.lastname: Hook
authors.forename: M J
authors.initials: MJ
authors.lastname: Mulligan
mesh_terms: D016915:AIDS Vaccines; D000163:Acquired Immunodeficiency Syndrome / Q000517:prevention & control*; D000328:Adult; D001741:Black or African American; D000407:Alabama; D000704:Analysis of Variance; D002986:Clinical Trials as Topic; D003153:Community Health Services; D005260:Female; D015497:HIV-1; D020010:Heterosexuality; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D010342:Patient Acceptance of Health Care; D012309:Risk-Taking; D012749:Sexually Transmitted Diseases; D015144:Southeastern United States; D011795:Surveys and Questionnaires; D014505:Urban Population; D044465:White People
chemical_list: D016915:AIDS Vaccines