Stability of the Escherichia coli division inhibitor protein MinC requires determinants in the carboxy-terminal region of the protein.
Certain mutations in the C-terminal region of the Escherichia coli division inhibitor protein MinC cause loss of function of the division inhibitor by making MinC more sensitive to degradation by Lon protease, implying a possible role for the C-terminal region in regulating the stability and cellular concentration of MinC.
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Department of Microbiology, University of Connecticut Health Center, Farmington 06032, USA.
Rothfield
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D049069:ATP-Dependent Proteases; D001426:Bacterial Proteins / Q000032:analysis / Q000737:chemistry* / Q000235:genetics; D002455:Cell Division; D004926:Escherichia coli / Q000166:cytology* / Q000235:genetics; D029968:Escherichia coli Proteins; D006360:Heat-Shock Proteins / Q000378:metabolism; D009154:Mutation; D010641:Phenotype; D049070:Protease La; D012697:Serine Endopeptidases / Q000378:metabolism
D001426:Bacterial Proteins; D029968:Escherichia coli Proteins; D006360:Heat-Shock Proteins; C080466:MinC protein, Bacteria; D049069:ATP-Dependent Proteases; D012697:Serine Endopeptidases; C483567:Lon protein, E coli; D049070:Protease La