[Histofunctional state of the thyroid gland in pregnancy and in progeny under experimental regime of iodine intake].
The paper is devoted to the study of the character of structural changes in the thyroid gland in pregnancy and in progeny of rats with deficient or excessive intake of iodine. A stable model of thyroid transformation was developed under the conditions of the changed regimen of iodine intake in pregnancy. Predominantly proliferative changes of the epithelial component in the thyroid tissue developed in pregnancy both with deficient and excessive iodine. Based on the histochemical, morphometric, histostereometric analysis a close relationship between the character of transformation of maternal thyroid and the progeny thyroid tissue was found. Dynamics of the development of postnatal thyroid tissue in the presence of congenital structural-functional disorders is described.
Stepanov
S A
SA
Tupikina
E B
EB
D000818:Animals; D000831:Animals, Newborn; D005260:Female; D007455:Iodine / Q000008:administration & dosage*; D018811:Maternal Exposure; D011247:Pregnancy; D051381:Rats; D013959:Thyroid Diseases / Q000151:congenital; D013961:Thyroid Gland / Q000196:embryology / Q000473:pathology* / Q000503:physiopathology*
D007455:Iodine