Pentavalent technetium-99m dimercaptosuccinic acid uptake in primary amyloidosis: comparison with autopsy findings.
Pentavalent technetium-99m labeled dimercaptosuccinic acid (99mTc(V)-DMSA) scanning was performed on a 71-year-old woman with histologically confirmed primary amyloidosis. Definite uptake of the tracer was noted in the thyroid, liver, spleen, and kidney as well as in the heart. Three months later, she died of heart failure, and autopsy findings demonstrated diffuse deposits of AL-type amyloid in those organs that were consistent with the accumulation of 99mTc(V)-DMSA.
Yukihiro
M
M
Department of Nuclear Medicine, Gunma University School of Medicine, Maebashi, Japan.
Tateno
M
M
Hirano
T
T
Oriuchi
N
N
Inoue
T
T
Iwasaki
T
T
Murata
K
K
Fukuda
T
T
Nakajima
T
T
Endo
K
K
D000368:Aged; D000686:Amyloidosis / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D005500:Follow-Up Studies; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D007674:Kidney Diseases / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology; D008107:Liver Diseases / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology; D009206:Myocardium / Q000378:metabolism / Q000473:pathology; D010179:Pancreas / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics*; D013158:Splenic Diseases / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology; D019783:Technetium Tc 99m Dimercaptosuccinic Acid / Q000493:pharmacokinetics*; D013959:Thyroid Diseases / Q000000981:diagnostic imaging / Q000378:metabolism* / Q000473:pathology
D019275:Radiopharmaceuticals; D019783:Technetium Tc 99m Dimercaptosuccinic Acid