Nitrite- and chloride-selective fluorescent nano-optodes and in vitro application to rat conceptuses.
Nitrite- and chloride-selective, ion correlation-based, nano-optodes have been prepared for application in vitro. These fluorescent, liquid polymer based sensors have theoretically predictable responses to anion activities and good selectivity. The nitrite sensor, prepared with a vitamin B12 derivative ionophore, would be useful for determination of oxidized nitric oxide. Chloride nano-optodes, as well as micro-optodes, prepared with an indium porphyrin ionophore, were utilized to determine chloride levels both on the surface and inside the visceral yolk sac of organogenesis-stage rat conceptuses.
Barker
S L
SL
Department of Chemistry, University of Michigan, Ann Arbor 48109-1055, USA.
Thorsrud
B A
BA
Kopelman
R
R
D000818:Animals; D002712:Chlorides / Q000032:analysis*; D004622:Embryo, Mammalian / Q000737:chemistry*; D005260:Female; D005336:Fiber Optic Technology; D005456:Fluorescent Dyes / Q000737:chemistry*; D008839:Microelectrodes; D009573:Nitrites / Q000032:analysis*; D011247:Pregnancy; D051381:Rats
D002712:Chlorides; D005456:Fluorescent Dyes; D009573:Nitrites