title: Hepatitis C virus-associated mixed cryoglobulinaemia.
abstract: Symptomatic mixed cryoglobulinaemia may dominate the course of hepatitis C virus infection. While conventional treatment of mixed cryoglobulinaemia relied on immunosuppression, the discovery of the close association to HCV infection has prompted treatment studies with interferon-alpha. Although symptomatic improvement is achieved in most patients during therapy, the rate of sustained response is low.
authors.affiliation: Department of General Internal Medicine, University of Bonn, Germany.
authors.forename: F L
authors.initials: FL
authors.lastname: Dumoulin
authors.forename: U
authors.initials: U
authors.lastname: Spengler
authors.forename: T
authors.initials: T
authors.lastname: Sauerbruch
mesh_terms: D003449:Cryoglobulinemia / Q000175:diagnosis / Q000628:therapy* / Q000821:virology; D016174:Hepacivirus / Q000302:isolation & purification*; D006526:Hepatitis C / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D016898:Interferon-alpha / Q000627:therapeutic use*
chemical_list: D016898:Interferon-alpha