Neonatal seizures
The understanding of the clinical features and pathophysiology of neonatal seizures continues to evolve. Although further refinement is necessary, there now exists a working classification of neonatal seizures. Etiology is the major determinant of outcome and management should be primarily directed at the cause. Treatment of the seizures with antiepileptic drugs is controversial. The short and long term consequences of seizures and antiepileptic drug therapy on the developing brain are discussed in this article.
Holmes
GL
Department of Neurology, Children's Hospital, Boston, MA 02115, USA.