title: Psychoeducational psychotherapy for schizophrenic patients and their key relatives or care-givers: results of a 2-year follow-up.
abstract: Psychoeducational medication management training (PMT), cognitive psychotherapy (CP) and key-person counselling (KC) were carried out in various combinations in this randomized, controlled intervention study of schizophrenic out-patients (according to DSM-III-R). Special design characteristics of the study were a control group consisting of non-specifically treated patients and a 2-year follow-up after completion of treatment in order to evaluate medium-term effects. A total of 132 patients underwent a follow-up examination 2 years after completion of treatment and were evaluated with an intention-to-treat approach. In the second follow-up year, all treatment groups had lower but not significantly different relapse rates compared to the control group. The most intensive treatment (PMT+CP+KC) produces a clinically relevant reduction in rehospitalization rate (a 26% reduction compared to the control group). In comparison with the non-specifically treated control group, whose original effect decreased, at least a medium-term therapeutic effect was recorded in the treatment groups.
authors.affiliation: Department of Psychiatry, University of Tübingen, Germany.
authors.forename: G
authors.initials: G
authors.lastname: Buchkremer
authors.forename: S
authors.initials: S
authors.lastname: Klingberg
authors.forename: R
authors.initials: R
authors.lastname: Holle
authors.forename: H
authors.initials: H
authors.lastname: Schulze Mönking
authors.forename: W P
authors.initials: WP
authors.lastname: Hornung
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D017028:Caregivers / Q000193:education*; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003376:Counseling / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010349:Patient Compliance; D010353:Patient Education as Topic; D010359:Patient Readmission; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data; D012008:Recurrence; D012559:Schizophrenia / Q000188:drug therapy / Q000534:rehabilitation / Q000628:therapy*; D012565:Schizophrenic Psychology; D012917:Social Adjustment; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D014150:Antipsychotic Agents