title: Progression of choroidal atrophy in acute posterior multifocal placoid pigment epitheliopathy.
abstract: Acute posterior multifocal placoid pigment epitheliopathy is a non-granulomatous chorioretinitis of uncertain origin that occurs in healthy young adults. The prevailing opinion is that the disease has a good long-term prognosis for visual acuity because it is self-limiting and chorioretinal scars do not enlarge with time. A middle-aged adult male who had acute posterior multifocal placoid pigment epitheliopathy in one eye has been followed for 22 years. After apparent clinical healing of the placoid epithelial lesions, widespread severe choroidal atrophy with visual loss occurred and progressed over years without interruption. To our knowledge this is the second report of progressive deterioration of a supposedly self-limiting chorioretinal disease.
authors.affiliation: Department of Medico-Surgical Specialties, University of Perugia, School of Medicine, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Daniele
authors.forename: C
authors.initials: C
authors.lastname: Daniele
authors.forename: F
authors.initials: F
authors.lastname: Orcidi
authors.forename: A
authors.initials: A
authors.lastname: Tavano
mesh_terms: D000208:Acute Disease; D000328:Adult; D002829:Choroid / Q000473:pathology*; D018450:Disease Progression; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D015799:Gyrate Atrophy / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*; D006801:Humans; D008297:Male; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012164:Retinal Diseases / Q000150:complications* / Q000175:diagnosis