[Differences in the genetic control of the formation of induced chromosomal aberrations and mitotic exchanges].
The maternal effect of the mutation mus104D1 (defect of postreplication repair) on the yield of translocations involving heterochromatin breaks induced by irradiation of mature spermatozoa has been investigated. The mutation has been shown to bring about a threefold increase in the frequency of translocations. No significant maternal effect of this mutation on the frequency of mitotic exchanges induced by irradiation of mature hyperploid spermatozoa has been observed. This is in agreement with published evidence on properties of the mei41 mutation (allete mus104D1). However, our results are more accurate as both processes--formation of translocations and mitotic exchanges--were studied in the same tissue and at the same stage of development.
Omel'ianchuk
L V
LV
Volkova
E I
EI
D000483:Alleles; D002869:Chromosome Aberrations; D004260:DNA Repair; D006570:Heterochromatin / Q000528:radiation effects*; D006720:Homozygote; D006801:Humans; D008297:Male; D008938:Mitosis; D009154:Mutation; D015203:Reproducibility of Results; D013094:Spermatozoa / Q000528:radiation effects*; D014178:Translocation, Genetic
D006570:Heterochromatin