A succinylanthranilic acid ester and other bioactive constituents of Jolyna laminarioides.
Methyl 2-[propanamide-2'-methoxycarbonyl] benzoate, fucosterol, trans-phytol and p-formylphenol were isolated for the first time from a methanolic extract of Jolyna laminarioides. Methyl 2-[propanamide-2'-methoxycarbonyl]-benzoate exhibited chymotrypsin inhibitory activity and also found to be active against Escherichia coli and Shigella boydii. Fucosterol exhibited antifungal activity against Curvularia lunata, Stachybotrys atra and Microsporum canis.
Atta-Ur-Rahman
H.E.J. Research Institute of Chemistry, University of Karachi, Pakistan.
Choudhary
M I
MI
Majeed
A
A
Shabbir
M
M
Ghani
U
U
Shameel
M
M
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D000935:Antifungal Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D001547:Benzaldehydes / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D001565:Benzoates / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D002918:Chymotrypsin / Q000037:antagonists & inhibitors; D004926:Escherichia coli / Q000187:drug effects; D005658:Fungi / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D008864:Microsporum / Q000187:drug effects; D015394:Molecular Structure; D000459:Phaeophyceae / Q000737:chemistry*; D010836:Phytol / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D010936:Plant Extracts; D011480:Protease Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D012761:Shigella boydii / Q000187:drug effects; D013265:Stigmasterol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D001547:Benzaldehydes; D001565:Benzoates; D010936:Plant Extracts; D011480:Protease Inhibitors; C110234:methyl-2-(propanamide-2'-methoxycarbonyl)benzoate; D010836:Phytol; C015896:fucosterol; D013265:Stigmasterol; D002918:Chymotrypsin; C011483:4-hydroxybenzaldehyde