Are single-needle protocols equivalent to dual-needle protocols for platelet apheresis?
In light of the increasing demands being placed on cytapheresis donors and their occasional venous problems, it has become necessary to use 1-needle in addition to 2-needle separation techniques in thrombocytapheresis. We therefore compared five 1-needle and three 2-needle programs on four different cell separators and found that meanwhile both the platelet yields and the leukopenia (controlled by Nageotte chamber counting) of the products obtained with the 1-needle technique are equivalent to those obtained using the 2-needle technique, as long as the program is suitably adjusted.
Zingsem
J
J
Abteilung für Transfusionsmedizin, Friedrich-Alexander-Universität Erlangen, Germany.
Weisbach
V
V
Zeiler
T
T
Zimmermann
R
R
Neidhardt
B
B
Eckstein
R
R
D001772:Blood Cell Count; D006801:Humans; D007962:Leukocytes; D009339:Needles; D010983:Plateletpheresis / Q000295:instrumentation* / Q000379:methods*; D014019:Tissue Donors