title: Neuroimaging and neuropsychology of the striatum. Bridging basic science and clinical practice.
abstract: Neuroimaging and neuropsychology are complementary disciplines that provide powerful means for assessing the structure and function of corticostriatal systems. Findings from four model basal ganglia disorders--OCD, TS, HD, and PD--are reviewed. This survey is intended as a vehicle for illustrating the breadth of current clinical and research applications, as well as the potential for future advances. The perspectives brought by neuroimaging and neuropsychology serve as a natural bridge from the basic neuroscience to the clinical practice articles in this issue.
authors.affiliation: Department of Psychiatry, Massachusetts General Hospital, Boston, USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Rauch
authors.forename: C R
authors.initials: CR
authors.lastname: Savage
mesh_terms: D003072:Cognition Disorders / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D003342:Corpus Striatum / Q000033:anatomy & histology / Q000502:physiology; D006801:Humans; D006816:Huntington Disease / Q000150:complications / Q000473:pathology / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008569:Memory Disorders / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D009483:Neuropsychological Tests; D009488:Neurosciences / Q000379:methods; D009771:Obsessive-Compulsive Disorder / Q000150:complications / Q000473:pathology / Q000503:physiopathology; D010300:Parkinson Disease / Q000150:complications / Q000473:pathology / Q000503:physiopathology; D014055:Tomography, Emission-Computed; D015899:Tomography, Emission-Computed, Single-Photon; D005879:Tourette Syndrome / Q000150:complications / Q000473:pathology / Q000503:physiopathology