title: [Use of combined lidocaine and bupivacaine spinal-epidural anesthesia in vascular surgery of lower limbs].
abstract: The efficacy of combined spinal epidural anesthesia (CSEA) for femoral to distal artery bypass surgery is assessed. Thirty-eight patients were divided into 3 groups. CSE block was performed at L3-L4 (26G pensil-point spinal needle and 18G catheter). In group I (n = 14) blocking was induced with 20 mg of 1% lidocaine and maintained with 2% lidocaine through an epidural catheter. Group II (n = 15) received spinal plain 20 mg of 0.5% bupivacaine. In group III (n = 9) the initial dose of plain 0.5% bupivacaine was 3 ml (15 mg); 5 min after the first bolus the incremental dose of plain bupivacaine 3 ml (15 mg) was injected and spinal needle was withdrawn. Epidural 0.5% bupivacaine was injected as needed. Sensory blockade was assessed by the pinprick test. Two patients in group I (18.2%) were in need of general anesthesia (GA) (inadequate dissemination of solution in 1 case and catheter kinking in the other). In group II GA had to be performed in 1 case because surgery was longer than planned. In group III anesthesia was effective in all cases. The mean level of sensory block in group I was T11.2 +/- 0.4, in group II T9.4 +/- 0.5, and in group III T8.6 +/- 0.55 (p > 0.05). The mean dose of bupivacaine per segment in groups II and III was 1.47 +/- 0.08 and 2.08 +/- 0.01, respectively (p < 0.05), use of epidural catheter during surgery 40 and 11%, respectively (p < 0.05). Arterial pressure drop was 10.8, 14.1, and 11.6% in groups I, II, and III, respectively. The mean total dose was 735 +/- 89 mg (172 +/- 14 mg/h) in the lidocaine group, in group II 38.5 +/- 6.4 mg (10.25 +/- 1.15 mg/h), and in group III 32.8 +/- 2.8 mg (7.46 +/- 1.67 mg/h) (p < 0.05). No neurological problems or PDPH were observed in any of the patients and no vasoactive drugs were needed. CSEA is fit for anesthesia for peripheral vascular surgery. CSEA with double spinal injection is preferable, for it provides a longer anesthesia and hemodynamic stability.
authors.forename: E Iu
authors.initials: EIu
authors.lastname: Gallinger
authors.forename: M N
authors.initials: MN
authors.lastname: Seleznev
authors.forename: G V
authors.initials: GV
authors.lastname: Babalian
mesh_terms: D000328:Adult; D000368:Aged; D000767:Anesthesia, Epidural; D000775:Anesthesia, Spinal; D000779:Anesthetics, Local / Q000008:administration & dosage*; D019917:Blood Vessel Prosthesis Implantation; D002045:Bupivacaine / Q000008:administration & dosage*; D003627:Data Interpretation, Statistical; D005069:Evaluation Studies as Topic; D006439:Hemodynamics; D006801:Humans; D007866:Leg / Q000098:blood supply / Q000601:surgery*; D008012:Lidocaine / Q000008:administration & dosage*; D008875:Middle Aged; D014656:Vascular Surgical Procedures
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine; D002045:Bupivacaine