False discoveries in genome scanning.
Methods of multiple comparisons were applied to linkage analysis in the case of genome scanning. Data for Problem 2A were used. p-Values were calculated for all 440,400 possible tests of linkage. Plots of distribution functions and false discovery rate are shown.
Drigalenko
E I
EI
Department of Epidemiology and Biostatistics, Rammelkamp Center for Education and Research, Case Western Reserve University, Cleveland, Ohio 44109-1998, USA.
Elston
R C
RC
D002874:Chromosome Mapping; D005260:Female; D008040:Genetic Linkage; D005819:Genetic Markers; D005820:Genetic Testing / Q000379:methods*; D015894:Genome, Human; D006801:Humans; D016014:Linear Models; D008297:Male; D016555:Matched-Pair Analysis; D009679:Nuclear Family; D011237:Predictive Value of Tests; D019655:Quantitative Trait, Heritable; D012044:Regression Analysis; D012984:Software
D005819:Genetic Markers