[Correlation of umbilical artery erythropoietin levels during labor with traditional indicators of neonatal hypoxia].
OBJECTIVE
To assess a correlation between the erythropoietin (Epo) level in umbilical blood during delivery and three "classical" markers of hypoxia: the Apgar score, pH in the umbilical artery and lactate concentration.


METHODS
The above parameters were assessed in 109 deliveries divided into three groups-normal deliveries, deliveries with neonatal pathology at term and premature deliveries.


RESULTS
Based on calculation of Spearman correlations which seemed most suitable with regard to the nature of the experimental data no significant relations were found between Epo and any of the mentioned parameters, while the mutual correlations between the Apgar score, pH of the umbilical artery and lactate were highly significant.


CONCLUSIONS
Epo is an independent marker of foetal hypoxia and supplementation of "classical" markers by this examination could be an asset to the evaluation of the prognosis of postnatal development.
Fingerová
H
H
Gynek.-porod. klinika LF UP a FN, Olomouc.
Zupková
H
H
D001238:Asphyxia Neonatorum / Q000097:blood / Q000175:diagnosis*; D015415:Biomarkers / Q000097:blood*; D004921:Erythropoietin / Q000097:blood*; D005311:Fetal Hypoxia / Q000175:diagnosis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007231:Infant, Newborn; D014469:Umbilical Arteries
D015415:Biomarkers; D004921:Erythropoietin