[The efficacy of combined immunocorrection in patients undergoing a treatment for chronic epitympanitis].
Ninety six patients with chronic epitympanitis treated surgically were examined immunologically and allocated in 4 groups. Suppressed T- and B-cell immunities were found. Patients of group 1 received antibiotics and antihistamine drugs (controls), patients of group 2, 3 and 4 were given in addition timontin, myelopid and timontin + myelopid, respectively. Monotherapy with timontin and myelopid improved immunological status of the patients who exhibited better outcomes of conventional treatment than controls. Combined use of the above immunomodulators corrected the immunological defects and resulted in good clinical response.
Pogosov
V S
VS
Kafedra LOR-bolezneĭ RMAPO, Voronezhskaia oblastnaia klinicheskaia bol'nitsa.
Poliakova
S D
SD
D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D001402:B-Lymphocytes / Q000187:drug effects*; D002908:Chronic Disease; D006801:Humans; D010033:Otitis Media / Q000188:drug therapy* / Q000276:immunology*; D013601:T-Lymphocytes / Q000187:drug effects*; D014432:Tympanic Membrane / Q000276:immunology*
D000900:Anti-Bacterial Agents