Utilization of thermoluminescent dosimetry in total skin electron beam radiotherapy of mycosis fungoides.
OBJECTIVE
The purpose of this report is to discuss the utilization of thermoluminescent dosimetry (TLD) in total skin electron beam (TSEB) radiotherapy to: (a) compare patient dose distributions for similar techniques on different machines, (b) confirm beam calibration and monitor unit calculations, (c) provide data for making clinical decisions, and (d) study reasons for variations in individual dose readings.


METHODS
We report dosimetric results for 72 cases of mycosis fungoides, using similar irradiation techniques on two different linear accelerators. All patients were treated using a modified Stanford 6-field technique. In vivo TLD was done on all patients, and the data for all patients treated on both machines was collected into a database for analysis. Means and standard deviations (SDs) were computed for all locations. Scatter plots of doses vs. height, weight, and obesity index were generated, and correlation coefficients with these variables were computed.


RESULTS
The TLD results show that our current TSEB implementation is dosimetrically equivalent to the previous implementation, and that our beam calibration technique and monitor unit calculation is accurate. Correlations with obesity index were significant at several sites. Individual TLD results allow us to customize the boost treatment for each patient, in addition to revealing patient positioning problems and/or systematic variations in dose caused by patient variability. The data agree well with previously published TLD results for similar TSEB techniques.


CONCLUSIONS
TLD is an important part of the treatment planning and quality assurance programs for TSEB, and routine use of TLD measurements for TSEB is recommended.
Antolak
J A
JA
Department of Radiation Physics, The University of Texas M. D. Anderson Cancer Center, Houston 77030, USA.
Cundiff
J H
JH
Ha
C S
CS
D004583:Electrons / Q000627:therapeutic use; D006801:Humans; D009182:Mycosis Fungoides / Q000532:radiotherapy*; D010315:Particle Accelerators; D012878:Skin Neoplasms / Q000532:radiotherapy*; D013819:Thermoluminescent Dosimetry; D014916:Whole-Body Irradiation