Difference between lambs with chronic and mild dermatophilosis in frequency of alleles of CD3 gamma.
Southern blots prepared with DNA from 20 Merino lambs that previously had chronic dermatophilosis (chronic) and 20 lambs that previously had mild dermatophilosis lesions (resistant) were hybridised with DNA sequences of the genes for the T-cell receptor-beta (TCR beta), a TCR-associated peptide 'cluster designation 3 gamma chain' (CD3 gamma) and ovine Major Histocompatibility Complex class 1 (ov. MHC class 1). There was a significant difference in the incidence of an allele of CD3 gamma between the chronic and resistant lambs. No significant difference in the incidence of alleles of TCR beta or ov. MHC class 1 was detected.
Masters
A M
AM
Animal Health Laboratories, Agriculture W.A., South Perth, Australia.
Ellis
T M
TM
Groth
D
D
D000193:Actinomycetales Infections / Q000235:genetics / Q000276:immunology / Q000662:veterinary*; D000483:Alleles; D000818:Animals; D002908:Chronic Disease; D004196:Disease Outbreaks / Q000662:veterinary; D005260:Female; D005787:Gene Frequency; D017260:Receptor-CD3 Complex, Antigen, T-Cell / Q000235:genetics*; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000235:genetics*; D012756:Sheep; D012757:Sheep Diseases; D017192:Skin Diseases, Bacterial / Q000235:genetics / Q000276:immunology / Q000662:veterinary*
D017260:Receptor-CD3 Complex, Antigen, T-Cell; D016693:Receptors, Antigen, T-Cell, alpha-beta