title: Influence of filtration on platelet transfusion reactions. Northern Ireland Haematology Audit Group [corrected].
abstract: In a retrospective analysis two methods for preventing platelet transfusion reactions are compared. The first group of patients received platelets filtered in the hospital blood bank and were subsequently given filtered and washed platelets if they developed reactions. The second group received platelets filtered at the bedside. In the group receiving platelets filtered in the hospital blood bank there was a very low rate of reaction (2/101 = 2%) and no patients receiving filtered and washed platelets (0/91) developed a reaction. In the group receiving platelets filtered at the bedside there was a reaction rate of 19/95 (20%). Further, two of these reactions were categorised as very severe, the patients showing hypotensive collapse. We conclude that filtering platelets in the hospital blood bank is significantly more effective than bedside filtration in preventing platelet transfusion reactions.
authors.affiliation: Northern Ireland Blood Transfusion Service (NIBTS), Belfast City Hospital Complex.
authors.forename: K
authors.initials: K
authors.lastname: Morris
authors.forename: C
authors.initials: C
authors.lastname: Bharucha
mesh_terms: D000328:Adult; D005334:Fever / Q000209:etiology; D005374:Filtration / Q000295:instrumentation; D006461:Hemolysis; D006801:Humans; D017713:Platelet Transfusion / Q000009:adverse effects* / Q000295:instrumentation* / Q000379:methods; D012189:Retrospective Studies