[Chromosomal aberrations in prenatal diagnosis--results of karyotyping 2,000 samples of amniotic fluid].
The frequencies of different types of chromosomal abnormalities are shown in a study performed during 1989-1996. 32 pathological karyotypes were found, i.e. 1.6%. The ratio of numerical/structural abnormalities is 1.67. The number of de novo or unexpected structural abnormalities is 67% from all structural ones in this study. This strongly supports the need of complete cytogenetic analysis.
Horácek
J
J
Ustav lékarské genetiky IPVZ, Praha, Krc.
Becvárová
V
V
Svĕtnicová
K
K
D000649:Amniocentesis; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007621:Karyotyping; D011247:Pregnancy