Autocatalytic removal of the pro-sequence from kexins requires an intact P-domain.
Powner
D
D
Department of Biological Sciences, University of Warwick, Coventry, UK. PDJT@dna.bio.warwick.ac.uk
Davey
J
J
D000409:Alanine; D019943:Amino Acid Substitution; D000818:Animals; D001665:Binding Sites; D002384:Catalysis; D002474:Cell-Free System; D005260:Female; D016297:Mutagenesis, Site-Directed; D009865:Oocytes / Q000502:physiology; D043484:Proprotein Convertases; D014176:Protein Biosynthesis; D011499:Protein Processing, Post-Translational; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000737:chemistry / Q000378:metabolism; D029701:Saccharomyces cerevisiae Proteins; D012568:Schizosaccharomyces / Q000201:enzymology*; D012694:Serine; D013381:Subtilisins / Q000096:biosynthesis / Q000737:chemistry* / Q000378:metabolism*; D014981:Xenopus
D011994:Recombinant Proteins; D029701:Saccharomyces cerevisiae Proteins; D012694:Serine; D043484:Proprotein Convertases; D013381:Subtilisins; C091268:krp dibasic endopeptidase; C058751:KEX2 protein, S cerevisiae; D000409:Alanine