[An analysis of the treadmill exercise test in a population of mild and moderate extrinsic asthmatics].
The bronchial response to physical exercise on a treadmill was analyzed in 48 patients with mild to moderate extrinsic asthma diagnosed by clinical criteria and a positive methacholine test, and in 36 non-asthmatic subjects. Bronchoconstriction secondary to physical exercise was documented by measuring the percent fall in PEF in different post-exercise control times. Significant differences (p < 0.00001) were observed between bronchial response in asthmatic and non-asthmatic patients. By using ROC curves an optimal cut-off was obtained in a fall equal to or greater than 6% 10 minutes post-exercise, with a sensitivity of 0.75 and an specificity of 0.923. The bronchial challenge test with physical exercise on a treadmill, within the limits of the studied sample, can be used as a method for detecting BHR in asthmatic patients.
Arias Irigoyen
J
J
Servicio de Medicina Preventiva, Hospital Clínico Universitario, Zaragoza.
Moliner Lahoz
J
J
Duce Gracia
F
F
D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000175:diagnosis* / Q000503:physiopathology; D016535:Bronchial Hyperreactivity / Q000175:diagnosis; D002648:Child; D005080:Exercise Test / Q000379:methods / Q000706:statistics & numerical data; D006801:Humans; D012372:ROC Curve; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric