Secretion: dense-core vesicles can kiss-and-run too.
New measurements show that the entire transmitter contents of a dense-core vesicle can be released within a second through a narrow fusion pore that opens transiently. With other results, this raises the possibility that some dense core vesicles may, like small synaptic vesicles, undergo immediate recycling.
Artalejo
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Department of Pharmacology, Wayne State University, Detroit, Michigan 48201, USA.
Elhamdani
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Palfrey
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HC
D002395:Catecholamines / Q000378:metabolism; D015550:Cell Degranulation; D005089:Exocytosis / Q000502:physiology*; D008954:Models, Biological; D018377:Neurotransmitter Agents / Q000378:metabolism*; D015388:Organelles / Q000378:metabolism*
D002395:Catecholamines; D018377:Neurotransmitter Agents