[Current technology of radiotherapy in the conservative treatment of localized breast cancer].
New procedures of radical radiotherapy for localized breast tumors have been developed. They offer high precision and a close fit of irradiation fields. Conservative treatment was given to 108 patients. Five- and ten year-survival, recurrence-free, following radical chemoradiation therapy was 30.2 and 14.1%, respectively: overall survival--33.6 and 15.5%, respectively. No signs of locoregional progression of tumor was observed in 77.5%. An evaluation of the results of complex treatment including obligatory mastectomy and those of conservative therapy revealed obvious advantages of the former in dealing with T3N1-2M0 tumors. However, no advantage was recorded in the treatment of T4N1-2M0 tumors. Radical chemo-radiotherapy of localized T4N1-2 tumors or respective single supraclavicular lymph nodes may be considered an alternative to modalities including mastectomy, provided all procedural and technological requirements are met.
Khmelevskiĭ
E V
EV
Kharchenko
V P
VP
Pan'shin
G A
GA
D001943:Breast Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D009367:Neoplasm Staging; D011879:Radiotherapy Dosage; D016019:Survival Analysis; D016896:Treatment Outcome