title: [The effect of phytogenic brassinosteroid steroidal hormones on transport of 86Rb+ ions into human erythrocytes].
abstract: The uptake of 86Rb+ ions by human erythrocytes as the measure of inhibition or stimulation of Na+, K(+)-ATPase by synthetic brassinolides, steroid fytohormonal promotors, was determined. No compound of the 12 tested brassinosteroids exerted higher inhibition of ATPase than digitoxin. A lower but significant inhibition of ion transport by 3 of tested derivatives, and a stimulation by 4 compounds was found. All active compounds were steroids with a 7-membered B-ring with an oxygen atom in the position 7a and with an oxogroup in position 6, i.e. they contained an lactone ring which is characteristic for natural brassinosteroids.
authors.affiliation: Endokrinologický ústav, Praha, Czech Republic.
authors.forename: L
authors.initials: L
authors.lastname: Stárka
authors.forename: V
authors.initials: V
authors.lastname: Schreiber
authors.forename: L
authors.initials: L
authors.lastname: Kohout
mesh_terms: D000251:Adenosine Triphosphatases / Q000037:antagonists & inhibitors; D004912:Erythrocytes / Q000378:metabolism*; D006801:Humans; D017136:Ion Transport / Q000187:drug effects; D010937:Plant Growth Regulators / Q000494:pharmacology*; D012413:Rubidium / Q000378:metabolism*
chemical_list: D010937:Plant Growth Regulators; D000251:Adenosine Triphosphatases; D012413:Rubidium