title: [Evaluation of tumor necrosis factor and C-reactive protein level determination in cerebrospinal fluid of meningitis and encephalitis].
abstract: The evaluation of TNF-alpha and CRP in cerebrospinal fluid (CSF) concentrations determining in the differential diagnosis of infectious meningitis was shown. The highest concentrations of these parameters were detected in the group of patients with bacterial meningitis. The findings correlated with the severity of clinical course of bacterial meningitis and with the routine determined laboratory data of CSF. Usefulness of examination CSF for TNF-alpha and CRP in differential diagnosis of meningitis was underlined, especially in cases, where routine parameters of CSF are not conclusive.
authors.affiliation: I Kliniki Chorób Zakaźnych Slaskiej Akademii Medycznej w Bytomiu.
authors.forename: L
authors.initials: L
authors.lastname: Kepa
authors.forename: B
authors.initials: B
authors.lastname: Adamek
mesh_terms: D000328:Adult; D002097:C-Reactive Protein / Q000134:cerebrospinal fluid*; D003937:Diagnosis, Differential; D004660:Encephalitis / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000134:cerebrospinal fluid / Q000175:diagnosis*; D008875:Middle Aged; D014409:Tumor Necrosis Factor-alpha / Q000134:cerebrospinal fluid*
chemical_list: D014409:Tumor Necrosis Factor-alpha; D002097:C-Reactive Protein