title: Cellulitis due to Streptococcus pneumoniae with diminished susceptibility to penicillin in an immunocompromised patient.
abstract: A 74-year-old man with multiple myeloma developed facial and cervical cellulitis and severe sepsis as a complication of surgery (alar region basal cell carcinoma). The etiological agent was, surprisingly, penicillin-resistant Streptococcus pneumoniae (PRSP). The patient successfully received 16 days of antibiotics. Amoxicillin was given as monotherapy during the last 14 days of treatment. PRSP can be responsible not only for otitis media, pneumonia or meningitis, but also for various other types of infection in patients with predisposing factors.
authors.affiliation: Service de Réanimation Polyvalente, Hôpital G. Montpied, Clermont-Ferrand, France.
authors.forename: B
authors.initials: B
authors.lastname: Souweine
authors.forename: T
authors.initials: T
authors.lastname: Mom
authors.forename: L
authors.initials: L
authors.lastname: Bret
authors.forename: A
authors.initials: A
authors.lastname: Klisnick
authors.forename: J C
authors.initials: JC
authors.lastname: Baguet
authors.forename: L
authors.initials: L
authors.lastname: Gilain
mesh_terms: D000368:Aged; D002481:Cellulitis / Q000188:drug therapy / Q000276:immunology / Q000382:microbiology*; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D010403:Penicillin Resistance; D010406:Penicillins / Q000494:pharmacology / Q000627:therapeutic use*; D011008:Pneumococcal Infections / Q000188:drug therapy* / Q000276:immunology; D013296:Streptococcus pneumoniae / Q000187:drug effects*
chemical_list: D010406:Penicillins