Molecular basis for the resistance of fibrin-bound thrombin to inactivation by heparin/serpin complexes.
Becker
D L
DL
Hamilton Civic Hospitals Research Centre, Ontario, Canada.
Fredenburgh
J C
JC
Stafford
A R
AR
Weitz
J I
JI
D000818:Animals; D000925:Anticoagulants / Q000627:therapeutic use; D001665:Binding Sites; D003327:Coronary Disease / Q000188:drug therapy; D005337:Fibrin / Q000502:physiology*; D006493:Heparin / Q000494:pharmacology* / Q000627:therapeutic use; D024764:Hirudin Therapy; D006801:Humans; D015843:Serpins / Q000494:pharmacology*; D013917:Thrombin / Q000037:antagonists & inhibitors / Q000378:metabolism*; D013927:Thrombosis / Q000503:physiopathology
D000925:Anticoagulants; D015843:Serpins; D005337:Fibrin; D006493:Heparin; D013917:Thrombin