title: Practical considerations in the early treatment of ischemic stroke.
abstract: Successful treatment of patients with ischemic stroke depends on the ability to treat within three hours of onset, because tissue plasminogen activator has not yet been proved effective beyond this time frame. The two major causes of delay in treatment are failure, on the part of the patient or family, to recognize stroke symptoms and failure to access the medical system most efficiently--by calling 911. Hospital stroke teams can shorten the time between patient arrival at the emergency department and treatment. Guidelines for the evaluation and treatment of potential stroke patients are presented, along with goal times for arrival-to-treatment intervals.
authors.affiliation: University of Cincinnati Medical Center, Ohio, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Broderick
mesh_terms: D000208:Acute Disease; D002543:Cerebral Hemorrhage / Q000139:chemically induced; D002561:Cerebrovascular Disorders / Q000188:drug therapy / Q000628:therapy*; D000075202:Contraindications; D019091:Critical Pathways; D004636:Emergency Service, Hospital; D006801:Humans; D009203:Myocardial Infarction / Q000628:therapy; D018579:Patient Selection; D017410:Practice Guidelines as Topic; D015912:Thrombolytic Therapy / Q000592:standards*; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D010959:Tissue Plasminogen Activator