title: Cutaneous epithelioid hemangioendothelioma, epithelioid cell histiocytoma and Spitz nevus. Three separate epithelioid tumors in one patient.
abstract: We report the unusual history of a young lady who, over a period of 9 years, developed 3 epithelioid neoplasms of different histiogenetic origin: a cutaneous epithelioid hemangioendothelioma, an epithelioid cell histiocytoma, and a Spitz nevus. To the best of our knowledge, such an unusual combination of neoplasms has not been reported previously and raises the question of an underlying "epithelioid" reaction pattern responsible for the epithelioid appearance in all 3 tumors; the likelihood of such a combination of tumors occurring in a single patient would be less than 1 in 1 billion.
authors.affiliation: Department of Pathology, University of Innsbruck, Austria.
authors.forename: B G
authors.initials: BG
authors.lastname: Zelger
authors.forename: B
authors.initials: B
authors.lastname: Wambacher
authors.forename: H
authors.initials: H
authors.lastname: Steiner
authors.forename: B
authors.initials: B
authors.lastname: Zelger
mesh_terms: D000328:Adult; D005260:Female; D018323:Hemangioendothelioma, Epithelioid / Q000473:pathology*; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology*; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D018332:Nevus, Epithelioid and Spindle Cell / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*