title: [Preoperative radiotherapy in cancer of the rectum. Our 5-year experience].
abstract: Since 1990, 41 patients with rectal carcinoma have been submitted to preoperative radiotherapy, which induced a shrinkage of the tumor, favouring its surgical resection. Besides, in 3 cases the operative specimens were tumor free, and a higher incidence of A and B 1 categories was found. Surgical results have been compared with an analogous group of 20 patients, where surgery was performed as a first procedure, then followed by radiotherapy in 9. No increase of postoperative complications was observed. While analysis of follow-up results demonstrates a decrease of tumour recurrence in patients with preoperative radiotherapy, no difference in survival was registered, because of the development of extra-pelvic metastases.
authors.affiliation: Cattedra di Chirurgia d'Urgenza, Università degli Studi, Modena.
authors.forename: A
authors.initials: A
authors.lastname: Manenti
authors.forename: M
authors.initials: M
authors.lastname: Gavioli
authors.forename: M
authors.initials: M
authors.lastname: Santantonio
authors.forename: M
authors.initials: M
authors.lastname: Parmiggiani
authors.forename: G
authors.initials: G
authors.lastname: Mandolini
authors.forename: A
authors.initials: A
authors.lastname: Falchi
authors.forename: R
authors.initials: R
authors.lastname: Miselli
authors.forename: C
authors.initials: C
authors.lastname: Gabrielli
authors.forename: G
authors.initials: G
authors.lastname: Luppi
authors.forename: A C
authors.initials: AC
authors.lastname: Rosi
authors.forename: I
authors.initials: I
authors.lastname: Piccagli
authors.forename: M
authors.initials: M
authors.lastname: Romani
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003125:Colostomy; D003131:Combined Modality Therapy; D003627:Data Interpretation, Statistical; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D011183:Postoperative Complications; D011300:Preoperative Care; D011879:Radiotherapy Dosage; D012004:Rectal Neoplasms / Q000401:mortality / Q000532:radiotherapy* / Q000601:surgery*; D013997:Time Factors