[Computed tomographic correlates of the cognitive disorders in Parkinson disease].
There were observed of 88 patients with Parkinson's disease. According to data of computer tomography 3 groups of patients were determined: with external type of cerebral atrophy (CA) mainly, with internal type of CA mainly and combined type too. Neuropsychologic study revealed differences among CA types both in degree of manifestation and in character of alteration of high mental functions. Together with neuropsychologic symptoms of the damages of mediobasal structures which were quite characteristic for this disease, there were also revealed the damages of convex cortical areas of frontal, parietal and temporal lobes. Pathologic inertia, inactivity of remembering and impairment of the processes of generalization were found more frequently at internal type of CA. Meanwhile at external CA type both difficulties of learning and disorders of motor programs' control were observed. The obvious correlations were also established between the degree of cognitive alterations and a presence of CA. Moreover, CA type had certain influence mainly on the structure but not on the manifestation of the cognitive disorders.
Sadikova
O N
ON
Glozman
Zh M
ZhM
D000368:Aged; D001284:Atrophy / Q000150:complications / Q000000981:diagnostic imaging / Q000523:psychology; D001921:Brain / Q000000981:diagnostic imaging / Q000473:pathology; D003072:Cognition Disorders / Q000000981:diagnostic imaging* / Q000209:etiology / Q000523:psychology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000150:complications / Q000000981:diagnostic imaging* / Q000523:psychology; D014057:Tomography, X-Ray Computed