title: Late onset paraplegia--a sequela to Pott's disease. A report on imaging, prevention and management.
abstract: Late onset paraplegia is a neurological complication that develops after a variable period in a patient with healed tuberculous disease of the vertebrae. In this retrospective analysis clinical features, imaging in diagnosis and treatment of this condition are described among 5 cases seen over a period of 5 years. This complication occurred even after successful treatment of initial spinal lesions with rifampicin-containing regimens. Magnetic resonance imaging was useful in pinpointing the exact pathology; one case had syrinx and two cases had marked internal gibbus with cord atrophy. Of the two cases who accepted surgical treatment, one improved.
authors.affiliation: Tuberculosis Research Centre, Madras, India.
authors.forename: R
authors.initials: R
authors.lastname: Rajeswari
authors.forename: R
authors.initials: R
authors.lastname: Ranjani
authors.forename: T
authors.initials: T
authors.lastname: Santha
authors.forename: K
authors.initials: K
authors.lastname: Sriram
authors.forename: R
authors.initials: R
authors.lastname: Prabhakar
mesh_terms: D000293:Adolescent; D000995:Antitubercular Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009192:Myelography; D010264:Paraplegia / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D012189:Retrospective Studies; D013904:Thoracic Vertebrae; D013997:Time Factors; D014399:Tuberculosis, Spinal / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology
chemical_list: D000995:Antitubercular Agents