Lymphocytic thyroiditis in beagle dogs in a breeding colony: findings of serum autoantibodies.
Three serum autoantibodies against antigens of the thyroid gland were detected by the indirect immunofluorescence in a Beagle dog breeding colony. The anti-thyroglobulin autoantibody was present in 10.0%, the anti-microsomal antigen autoantibody was present in 24.6%, and the anti-nuclear substance autoantibody in 10.8% of examined sera, respectively. Only the presence of anti-thyroglobulin autoantibodies could be correlated with histologic findings of the lymphocytic thyroiditis in the same colony.
Vajner
L
L
Institute of Histology and Embryology, 2nd Faculty of Medicine, Charles University, Praha, Czech Republic. Ludek.Vajner@lfmotol.cuni.cz
D000818:Animals; D001323:Autoantibodies / Q000032:analysis*; D004283:Dog Diseases / Q000235:genetics* / Q000276:immunology; D004285:Dogs; D005260:Female; D008297:Male; D013967:Thyroiditis, Autoimmune / Q000235:genetics / Q000276:immunology / Q000662:veterinary*
D001323:Autoantibodies