Effects of aging and drugs on normal renal function.
The aging kidney is associated with a number of structural and functional changes. As a result of these changes the aging kidney is more susceptible to nephrotoxic and ischemic injury. We will review the structural and functional changes that occur with aging and then review the salient features of acute renal failure in the elderly population.
Lash
J P
JP
Section of Nephrology University of Illinois at Chicago, USA.
Gardner
C
C
D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000503:physiopathology / Q000628:therapy; D000368:Aged; D000375:Aging / Q000502:physiology*; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects; D005260:Female; D006801:Humans; D007668:Kidney / Q000187:drug effects / Q000502:physiology*; D007677:Kidney Function Tests; D008297:Male; D011379:Prognosis; D012016:Reference Values
D000806:Angiotensin-Converting Enzyme Inhibitors; D000894:Anti-Inflammatory Agents, Non-Steroidal