title: Structure of D-amino acid oxidase: new insights from an old enzyme.
abstract: D-amino acid oxidase is the prototype of flavin-dependent oxidases. The recent resolution of its 3D structure has provided an explanation for several of its properties and has led to a substantial revision of the mechanism of D-amino acid dehydrogenation, with significant implications for the general understanding of flavin-dependent catalysis.
authors.affiliation: Dipartimento di Genetica e Microbiologia, Università di Pavia, Italy. mattevi@ipvgen.unipv.it
authors.forename: A
authors.initials: A
authors.lastname: Mattevi
authors.forename: M A
authors.initials: MA
authors.lastname: Vanoni
authors.forename: B
authors.initials: B
authors.lastname: Curti
mesh_terms: D001665:Binding Sites; D002384:Catalysis; D003605:D-Amino-Acid Oxidase / Q000737:chemistry* / Q000378:metabolism; D019143:Evolution, Molecular; D005420:Flavoproteins / Q000737:chemistry; D006860:Hydrogen Bonding; D008958:Models, Molecular; D017434:Protein Structure, Tertiary
chemical_list: D005420:Flavoproteins; D003605:D-Amino-Acid Oxidase