Chromosome dynamics: yeast pulls it apart.
Sister chromatid cohesion and chromosome condensation are both essential to the successful completion of mitosis. The recent identification and characterization of the yeast Mcd1p/Scc1p protein reveals a previously unsuspected mechanistic link between these processes.
Gottschling
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Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, Seattle, Washington 98109, USA.
Berg
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D000705:Anaphase / Q000502:physiology*; D000818:Animals; D002453:Cell Cycle; D018797:Cell Cycle Proteins / Q000502:physiology*; D002868:Chromosomal Proteins, Non-Histone; D015825:Chromosomes, Fungal / Q000502:physiology*; D005656:Fungal Proteins / Q000502:physiology*; D019185:Notophthalmus / Q000033:anatomy & histology; D009687:Nuclear Proteins; D010750:Phosphoproteins; D012441:Saccharomyces cerevisiae / Q000166:cytology* / Q000235:genetics; D029701:Saccharomyces cerevisiae Proteins; D013045:Species Specificity
D018797:Cell Cycle Proteins; D002868:Chromosomal Proteins, Non-Histone; D005656:Fungal Proteins; C490529:MCD1 protein, S cerevisiae; D009687:Nuclear Proteins; D010750:Phosphoproteins; D029701:Saccharomyces cerevisiae Proteins