title: Pure ovarian ependymoma: report of a case treated with surgery, chemotherapy, irradiation and hyperthermotherapy.
abstract: Ependymomas usually develop from neuroectodermal organs. Pure ovarian ependymoma is an extremely rare tumor. We report a patient with ovarian ependymoma who died at the age of 28, 9 years after initial surgery and subsequent intensive combination therapy (chemotherapy, irradiation and hyperthermotherapy) for repeated relapses and metastatic tumors. The diagnosis was confirmed by histopathological and immunohistochemical studies. For recurrent and persistent ependymoma, a combination of the treatment modalities described above is suggested to be beneficial in attenuating the rapid progress and spread of this disease.
authors.affiliation: Department of Obstetrics and Gynecology, Yokohama City University School of Medicine, Japan.
authors.forename: F
authors.initials: F
authors.lastname: Hirahara
authors.forename: M
authors.initials: M
authors.lastname: Yamanaka
authors.forename: E
authors.initials: E
authors.lastname: Miyagia
authors.forename: T
authors.initials: T
authors.lastname: Nakazawa
authors.forename: I
authors.initials: I
authors.lastname: Gorai
authors.forename: H
authors.initials: H
authors.lastname: Minaguchi
authors.forename: M
authors.initials: M
authors.lastname: Kakei
authors.forename: M
authors.initials: M
authors.lastname: Yamamoto
authors.forename: H
authors.initials: H
authors.lastname: Kitamura
mesh_terms: D000293:Adolescent; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D004806:Ependymoma / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D007150:Immunohistochemistry; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D011878:Radiotherapy