Nitrosamine carcinogenesis: rodent assays, quantitative structure-activity relationships, and human risk assessment.
Lewis
D F
DF
School of Biological Sciences, University of Surrey, Guildford, UK.
Brantom
P G
PG
Ioannides
C
C
Walker
R
R
Parke
D V
DV
D000478:Alkylation; D000818:Animals; D015197:Carcinogenicity Tests / Q000379:methods; D002273:Carcinogens / Q000737:chemistry / Q000633:toxicity*; D004247:DNA / Q000737:chemistry / Q000378:metabolism; D004052:Diethylnitrosamine / Q000633:toxicity*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007928:Lethal Dose 50; D009569:Nitric Oxide / Q000378:metabolism; D009602:Nitrosamines / Q000737:chemistry / Q000633:toxicity*; D051381:Rats; D018570:Risk Assessment; D013329:Structure-Activity Relationship
D002273:Carcinogens; D009602:Nitrosamines; D009569:Nitric Oxide; D004052:Diethylnitrosamine; D004247:DNA