[The effect of treatment with sulphur water from the spring in Wiesław in Busko-Solec on levels of lipids,the fibrinolytic system and thrombogenic platelet function in patients with arteriosclerosis].
29 patients with arteriosclerosis obliterans and elevated level of cholesterol and/or triglycerides in blood received undiluted sulphur water from the spring Wiesław in Busko-Solec at the dose of 50 ml 3 times a day for 4 weeks. Such a treatment resulted in statistically significant decrease of blood levels of cholesterol, triglycerides and LDL cholesterol. The concentration of HDL cholesterol did not change significantly. Moreover, therapy with sulphur water resulted in decreasing of platelet aggregability evoked by ADP and collagen, spontaneous platelet aggregability and increasing fibrinolytic activity of the blood (elongation of euglobulin clot lysis time). We concluded that orally administered sulphur water from the spring Wiesław in Busko-Solec may be an additional means of treatment of patients with arteriosclerosis obliterans and high levels of cholesterol and/or triglycerides.
Goszcz
A
A
Zakładu Farmakologii Klinicznej Katedry Farmakologii Collegium Medicum Uniwersytetu Jagiellońskiego.
Kostka-Trabka
E
E
Grodzińska
L
L
Sławiński
M
M
Bieroń
K
K
Jachym
R
R
Kucharski
K
K
Gryglewski
R J
RJ
D000328:Adult; D000368:Aged; D001161:Arteriosclerosis / Q000097:blood / Q000628:therapy*; D001452:Balneology; D002784:Cholesterol / Q000097:blood*; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D006801:Humans; D008875:Middle Aged; D010974:Platelet Aggregation; D011044:Poland; D014280:Triglycerides / Q000097:blood*
D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D002784:Cholesterol