The use of risperidone for psychosis and agitation in demented patients with Parkinson's disease.
This pilot study investigated effectiveness and tolerability of risperidone for the treatment of psychosis and agitation in 9 inpatients with Parkinson's disease and dementia. Investigators found risperidone to be effective and safe, without worsening extrapyramidal symptoms or further impairing cognition.
Workman
R H
RH
Veterans Affairs Medical Center, Houston, Texas 77030, USA. workman.richardvhvjr@houston.va.gov
Orengo
C A
CA
Bakey
A A
AA
Molinari
V A
VA
Kunik
M E
ME
D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003704:Dementia / Q000150:complications / Q000188:drug therapy* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D010300:Parkinson Disease / Q000150:complications* / Q000523:psychology; D010865:Pilot Projects; D011569:Psychiatric Status Rating Scales; D011595:Psychomotor Agitation / Q000188:drug therapy* / Q000209:etiology / Q000523:psychology; D018967:Risperidone / Q000009:adverse effects / Q000627:therapeutic use*
D014150:Antipsychotic Agents; D018967:Risperidone