[Effect of n-3 PUFA polyunsaturated fatty acids on the thymus of rats with severe protein depletion].
Severe protein deprivation at weaning provokes an arrest of cellular proliferation and maturation, and an increase of ADA and PNP activities in the thymus of growing rats. A 20% casein diet fed during 9 days was enough to reverse the effect on ADA and PNP. The supplementation with 24 mg/d of n-3 PUFA, was able to recover thymus' cellular proliferation and maturation.
Fernández
I
I
Cátedra de Nutrición, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.
Feliu
M S
MS
Pallaro
A N
AN
Slobodianik
N H
NH
D000818:Animals; D015525:Fatty Acids, Omega-3 / Q000627:therapeutic use*; D006128:Growth / Q000187:drug effects; D011502:Protein-Energy Malnutrition / Q000150:complications / Q000178:diet therapy*; D051381:Rats; D017208:Rats, Wistar; D013950:Thymus Gland / Q000187:drug effects*; D014886:Weaning
D015525:Fatty Acids, Omega-3