Influence of breast- and formula-feeding on plasma cholesterol precursor sterols throughout the first year of life.
We evaluated endogenous cholesterol synthesis and plasma lipid profile longitudinally from birth to 1 year old in infants who were exclusively breast-fed (n = 19) or formula-fed (n = 19) for the first 4 months of life. At 1 and 4 months of age, breast-fed infants had higher plasma total and low-density lipoprotein cholesterol and apolipoprotein B levels than formula-fed infants, whereas plasma mevalonate and lanosterol levels were not different between the two study groups.
Bianchi
C
C
Department of Pediatrics, Istituto Scientifico H San Raffaele, Italy.
Brambilla
P
P
Cella
D
D
Ragogna
F
F
Tettamanti
C
C
Del Puppo
M
M
Kienle
M G
MG
Chiumello
G
G
Ruotolo
G
G
D000704:Analysis of Variance; D001055:Apolipoproteins B / Q000097:blood; D001942:Breast Feeding; D016009:Chi-Square Distribution; D002784:Cholesterol / Q000097:blood*; D008078:Cholesterol, LDL / Q000097:blood; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005500:Follow-Up Studies; D006801:Humans; D007225:Infant Food; D007231:Infant, Newborn; D007558:Italy; D007810:Lanosterol / Q000097:blood; D008137:Longitudinal Studies; D008297:Male; D008798:Mevalonic Acid / Q000097:blood; D012016:Reference Values; D012044:Regression Analysis; D017678:Sex Distribution
D001055:Apolipoproteins B; D008078:Cholesterol, LDL; D007810:Lanosterol; D002784:Cholesterol; D008798:Mevalonic Acid