title: Gender-related considerations in clinical pharmacology and drug therapeutics.
abstract: The pharmacokinetics and pharmacodynamics in women are different from that in men because of women's unique anatomy and physiology. Recently, gender-related studies in clinical pharmacology have been emerging, supporting the observation of gender-induced variations in drug response. The hormonal fluctuations during a woman's life span may influence pharmacotherapy. Therefore, gender-related pharmacology should be taken into consideration when prescribing medication for a woman. Data from drug developmental studies, FDA approved label directions, and other clinical research evaluation women's responses to medications are necessary to make optimal pharmacotherapeutic decisions.
authors.affiliation: Center for Pharmaceutical Science and Technology, College of Pharmacy, University of Kentucky, Lexington, USA.
authors.forename: C X
authors.initials: CX
authors.lastname: Xie
authors.forename: L T
authors.initials: LT
authors.lastname: Piecoro
authors.forename: D P
authors.initials: DP
authors.lastname: Wermeling
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D004364:Pharmaceutical Preparations / Q000378:metabolism*; D010599:Pharmacokinetics; D012727:Sex Characteristics; D012737:Sex Factors
chemical_list: D004364:Pharmaceutical Preparations