title: Management of chylothorax.
abstract: BACKGROUND
  Chylothorax is a rare primary or secondary condition the optimum management of which remains uncertain.
  
  
  METHODS
  Twenty cases of chylothorax, including ten of primary chylothorax and ten secondary to either malignancy, subclavian vein thrombosis or lymphangioma treated between 1956 and 1986 have been reviewed.
  
  
  RESULTS
  Open pleurectomy was the most successful treatment in preventing reaccumulation of the effusion. Three patients had thoracic duct-azygous vein anastomoses, but all anastomoses were probably occluded within a year of surgery. Three patients have been lost to follow-up and five died within 2 years of their treatment, but 12 patients were alive and free from an effusion 3-22 years after treatment.
  
  
  CONCLUSIONS
  Patients with chylothorax should undergo lymphangiography to identify the cause and site of the lymphatic abnormality. Conservative treatment is successful in some patients but should be abandoned if the fluid loss exceeds 1.5 l/day for more than 5-7 days in an adult or more than 100 ml/day in a child. Parietal pleurectomy is the most successful treatment when no distinct chylous leak can be identified. Less commonly, an isolated chylous leak either in the chest or in the abdomen may be identified and this should be treated by direct ligation.
authors.affiliation: Department of Surgery, St. Thomas' Hospital, London, UK.
authors.forename: N L
authors.initials: NL
authors.lastname: Browse
authors.forename: D R
authors.initials: DR
authors.lastname: Allen
authors.forename: N M
authors.initials: NM
authors.lastname: Wilson
mesh_terms: D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002916:Chylothorax / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007223:Infant; D008202:Lymphangioma / Q000150:complications; D008220:Lymphography; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000150:complications; D013350:Subclavian Vein; D013927:Thrombosis / Q000150:complications