title: Transfusion management in pediatric and adolescent scoliosis surgery. Efficacy of autologous blood.
abstract: METHODS
  A retrospective review of consecutive pediatric and adolescent patients who required posterior spinal fusion to correct scoliosis.
  
  
  OBJECTIVE
  To 1) measure the participation of pediatric patients in predeposit programs for autologous and directed blood donation 2) to assess the success of autologous predonation in preventing allogeneic blood use, 3) to determine whether transfusion indications differed between patients who received allogeneic blood and those who received autologous blood, and 4) to assess factors that predict transfusion requirements during scoliosis surgery.
  
  
  BACKGROUND
  Authors of recent studies in adults have questioned whether transfusion of autologous blood is a cost-effective therapy when compared with the less-expensive alternative--transfusion of allogeneic blood. In children, the efficacy of autologous blood has not been assessed in a large population of surgical patients. In adults, the frequency of patient participation, the success of autologous donors in avoiding allogeneic transfusion, and the proportion of collected autologous units used during the perioperative period are measures used to establish the efficacy of autologous predonation programs.
  
  
  METHODS
  Hospital and clinic records for each patient who underwent posterior spinal fusion from September 1, 1989 through September 1, 1994 were reviewed. Blood bank consultation, autologous donation records, anesthesia records, surgical reports, and hospital records were reviewed. Seventy percent of patients (164 of 243) participated in autologous donation.
  
  
  RESULTS
  More than 90% of autologous donors successfully avoided receiving allogeneic blood. Patients with idiopathic scoliosis (n = 168) were more likely to participate in autologous donation (n = 144) and to avoid allogeneic blood (n = 135). Patients with neurologic causes of scoliosis more commonly used allogeneic or directed donation (56 of 75 patients). Nineteen patients with neuromuscular causes of scoliosis participated in autologous donation, but more than one half of this group (10 of 19 patients) required allogeneic blood in addition to autologous units.
  
  
  CONCLUSIONS
  Using measures of efficacy similar to those reported in studies of adults, autologous blood was found to be more effective in meeting the transfusion needs of pediatric patients who required posterior spinal fusion than in meeting those needs in adult surgical patients in previous studies.
authors.affiliation: Department of Anesthesia, Washington University School of Medicine at St. Louis Children's Hospital, USA.
authors.forename: D J
authors.initials: DJ
authors.lastname: Murray
authors.forename: R B
authors.initials: RB
authors.lastname: Forbes
authors.forename: M B
authors.initials: MB
authors.lastname: Titone
authors.forename: S L
authors.initials: SL
authors.lastname: Weinstein
mesh_terms: D000293:Adolescent; D001771:Blood Banks; D016063:Blood Loss, Surgical / Q000517:prevention & control; D001804:Blood Transfusion, Autologous; D002648:Child; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D010349:Patient Compliance; D019990:Perioperative Care; D012600:Scoliosis / Q000601:surgery*; D013123:Spinal Fusion