title: Calyxamines A and B, novel piperidine alkaloids from the Caribbean sea sponge Calyx podatypa.
abstract: Calyxamines A (1) and B (2) are 2,2,4,6,6-pentasubstituted piperidine alkaloids possessing novel carbon skeletons isolated from the marine sponge Calyx podatypa collected in Puerto Rico. Their structures, after derivatization with trifluoroacetic acid, have been determined by a combination of X-ray and spectroscopic methods. A plausible biogenetic pathway to the calyxamines is suggested.
authors.affiliation: Department of Chemistry, University of Puerto Rico, Río Piedras 00931-3346, USA. abrodrig@upracd.upr.clu.edu
authors.forename: A D
authors.initials: AD
authors.lastname: Rodríguez
authors.forename: O M
authors.initials: OM
authors.lastname: Cóbar
authors.forename: O L
authors.initials: OL
authors.lastname: Padilla
authors.forename: C L
authors.initials: CL
authors.lastname: Barnes
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D010880:Piperidines / Q000737:chemistry / Q000302:isolation & purification*; D011161:Porifera / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D010880:Piperidines; C110082:calyxamine A; C110083:calyxamine B