title: Fatal subarachnoid hemorrhage from an inflammatory cavernous carotid artery aneurysm: failure of conservative treatment after early diagnosis--case report.
abstract: Inflammatory carotid artery aneurysm is a rare complication of acute paranasal sinusitis. A 50-year-old female presented with a ruptured giant carotid artery aneurysm secondary to infection of the sphenoid sinus and cavernous sinus. She had been healthy until 5 days before admission, when she developed orbital phlegmon and meningitis. She received antibiotic therapy for 10 days. Computed tomography (CT) of the brain 2 days after admission showed no abnormality. However, repeat CT on day 6 showed a round isodense mass in the suprasellar cistern suggesting a cerebral aneurysm. Twelve days after admission, she suffered a fatal subarachnoid hemorrhage. Cerebral angiography revealed a giant left cavernous carotid artery aneurysm with a very irregular shape. Autopsy found sphenoid sinusitis and osteomyelitis extending into the cavernous sinuses. Diagnosis of bacterial inflammatory aneurysms before rupture is very important. Appropriate surgical intervention should be considered if there is enlargement of the original aneurysm or appearance of a new aneurysm indicating a potentially dangerous situation.
authors.affiliation: Department of Neurosurgery, National Defense Medical College, Saitama.
authors.forename: H
authors.initials: H
authors.lastname: Nawashiro
authors.forename: A
authors.initials: A
authors.lastname: Shimizu
authors.forename: K
authors.initials: K
authors.lastname: Shima
authors.forename: H
authors.initials: H
authors.lastname: Chigasaki
authors.forename: T
authors.initials: T
authors.lastname: Kaji
authors.forename: E
authors.initials: E
authors.lastname: Doumoto
authors.forename: Y
authors.initials: Y
authors.lastname: Fuse
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002343:Carotid Artery, Internal / Q000473:pathology*; D002426:Cavernous Sinus / Q000473:pathology*; D002533:Cerebral Angiography; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications* / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008581:Meningitis / Q000150:complications / Q000188:drug therapy; D008875:Middle Aged; D013345:Subarachnoid Hemorrhage / Q000209:etiology*; D013997:Time Factors
chemical_list: D000900:Anti-Bacterial Agents