title: Signal transduction by wild-type and leukemogenic Abl proteins.
authors.affiliation: Hematology-Oncology, Department of Medicine, UCLA School of Medicine, Los Angeles, CA 90095-1678, USA.
authors.forename: A B
authors.initials: AB
authors.lastname: Raitano
authors.forename: Y E
authors.initials: YE
authors.lastname: Whang
authors.forename: C L
authors.initials: CL
authors.lastname: Sawyers
mesh_terms: D017209:Apoptosis; D017871:Calcium-Calmodulin-Dependent Protein Kinases / Q000502:physiology; D002448:Cell Adhesion; D002453:Cell Cycle; D002471:Cell Transformation, Neoplastic; D004249:DNA Damage; D004789:Enzyme Activation; D016044:Fusion Proteins, bcr-abl / Q000502:physiology; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000503:physiopathology*; D019869:Phosphatidylinositol 3-Kinases / Q000502:physiology; D011485:Protein Binding; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; D053824:Protein Tyrosine Phosphatase, Non-Receptor Type 6; D017027:Protein Tyrosine Phosphatases / Q000502:physiology; D011505:Protein-Tyrosine Kinases / Q000502:physiology*; D011518:Proto-Oncogene Proteins / Q000502:physiology; D016315:Proto-Oncogene Proteins c-abl / Q000502:physiology*; D051562:Proto-Oncogene Proteins c-bcr; D050737:Proto-Oncogene Proteins c-crk; D016283:Proto-Oncogene Proteins p21(ras) / Q000502:physiology; D015398:Signal Transduction
chemical_list: D047908:Intracellular Signaling Peptides and Proteins; D011518:Proto-Oncogene Proteins; D050737:Proto-Oncogene Proteins c-crk; D019869:Phosphatidylinositol 3-Kinases; D011505:Protein-Tyrosine Kinases; D016044:Fusion Proteins, bcr-abl; D016315:Proto-Oncogene Proteins c-abl; C496613:BCR protein, human; D051562:Proto-Oncogene Proteins c-bcr; D017871:Calcium-Calmodulin-Dependent Protein Kinases; C516724:PTPN11 protein, human; C509249:PTPN6 protein, human; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; D053824:Protein Tyrosine Phosphatase, Non-Receptor Type 6; D017027:Protein Tyrosine Phosphatases; C501009:HRAS protein, human; D016283:Proto-Oncogene Proteins p21(ras)