title: Determination of bleeding risk in thrombocytopenic patients with platelet transfusion therapy.
abstract: In a clinical study (50 thrombocytopenic patients) we determined the bleeding risk and the platelet transfusion efficacy by a special modification of the in vitro bleeding test (IVBT, Thrombostat 4000). Additionally, cell count, hematocrit, body temperature, platelet volume and distribution width, Simplate bleeding time and a bleeding score were investigated. The use of the modified IVBT proved to be promising to find a clearer indication of platelet transfusion and to estimate its efficacy.
authors.affiliation: Department of Transfusion Medicine and Hemostaseology, University Hospital, Marburg, Germany.
authors.forename: V
authors.initials: V
authors.lastname: Kretschmer
authors.forename: B
authors.initials: B
authors.lastname: Huss
authors.forename: S
authors.initials: S
authors.lastname: Weber
authors.forename: S
authors.initials: S
authors.lastname: Bewarder
authors.forename: T
authors.initials: T
authors.lastname: Schulzki
authors.forename: H
authors.initials: H
authors.lastname: Köppler
authors.forename: J
authors.initials: J
authors.lastname: Heimanns
mesh_terms: D001760:Bleeding Time; D001772:Blood Cell Count; D001831:Body Temperature; D006470:Hemorrhage / Q000453:epidemiology*; D006801:Humans; D010976:Platelet Count; D017713:Platelet Transfusion / Q000009:adverse effects*; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood / Q000628:therapy*; D018570:Risk Assessment