title: Efficacy of intraoperative blood salvage during coronary artery bypass grafting.
abstract: OBJECTIVE
  To analyze the usefulness of autologous blood salvage and intraoperative isovolemic hemodilution in conjunction with autologous blood salvage in cardiac surgery, and also to compare two different autologous blood salvage methods.
  
  
  METHODS
  Retrospective analysis of transfusion practice in cardiac surgery.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  One hundred and sixty two consecutive patients who had coronary artery bypass grafting (CABG) from January to September, 1993.
  
  
  METHODS
  A review of transfusion records of patients who underwent intraoperative autologous blood salvage and isovolemic hemodilution.
  
  
  METHODS
  Perioperative transfusion requirements were analyzed in patients undergoing CABG using a cell saver system whereby blood was collected, processed and reinfused to the patients in the operating room.
  
  
  RESULTS
  Nineteen percent of patients did not receive perioperative homologous blood transfusion when a cell saver was used intraoperatively. When autologous isovolemic hemodilution was used in conjunction with a cell saver, fifty-four percent of the patients did not receive homologous blood transfusion. The results of this study were compared to matched patients undergoing CABG using a different type of cell saver system whereby blood was collected in the operating room, processed in the blood bank and reinfused in the intra- and/or postoperative period. We found that the former system provided a more timely and greater yield of blood salvaged and as a consequence, less homologous blood transfusion.
  
  
  CONCLUSIONS
  Intraoperative blood salvaging provides an immediate source of red blood cells and decreases the utilization of homologous blood. In addition, isovolemic hemodilution in conjunction with blood salvage further decreases homologous blood transfusion needs.
authors.affiliation: Department of Anesthesiology, St. Louis University, USA.
authors.forename: J
authors.initials: J
authors.lastname: Lee
authors.forename: S
authors.initials: S
authors.lastname: Ikeda
authors.forename: M F
authors.initials: MF
authors.lastname: Johnston
mesh_terms: D000368:Aged; D016063:Blood Loss, Surgical; D001793:Blood Preservation; D001804:Blood Transfusion, Autologous; D001026:Coronary Artery Bypass; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged