title: Childhood tumors.
abstract: Advances are slowly being made in the understanding and treatment of primary childhood brain tumors. The addition of chemotherapy has resulted in better survival for children with medulloblastoma. For other tumor types, therapeutic advances have been slower. High-dose chemotherapy is increasingly being employed to treat malignant childhood tumors, with variable results. Chemotherapy has been effective in low-grade glial tumors.
authors.affiliation: Department of Neurology, Children's National Medical Center, Washington, DC 20010, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Packer
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy / Q000628:therapy*; D002528:Cerebellar Neoplasms / Q000188:drug therapy / Q000532:radiotherapy; D002648:Child; D004806:Ependymoma / Q000628:therapy; D018237:Germinoma / Q000628:therapy; D006801:Humans; D008527:Medulloblastoma / Q000188:drug therapy / Q000532:radiotherapy; D016019:Survival Analysis; D016896:Treatment Outcome
chemical_list: D000970:Antineoplastic Agents