title: Unusual liver MR findings of Wilson's disease in an asymptomatic 2-year-old girl.
abstract: We describe the unusual magnetic resonance (MR) findings of a case of Wilson's disease (WD) in an asymptomatic 2-year-old girl. Preenhanced computed tomography revealed multiple hyperdense areas in the liver. These lesions were hyperintense on T1-weighted and hypointense on T2-weighted MR images, results that might be ascribed to the paramagnetism of copper deposited in liver at a relatively early stage of the disease before severe liver cirrhosis had evolved.
authors.affiliation: Department of Radiology, Chang Gung Memorial Hospital at Kaohsiung, Chang Gung College of Medicine and Technology, 123 Ta-Pei Road, Niao-Sung Hsiang, Kaohsiung Hsien 833, Taiwan.
authors.forename: S
authors.initials: S
authors.lastname: Ko
authors.forename: T
authors.initials: T
authors.lastname: Lee
authors.forename: S
authors.initials: S
authors.lastname: Ng
authors.forename: J
authors.initials: J
authors.lastname: Lin
authors.forename: Y
authors.initials: Y
authors.lastname: Cheng
mesh_terms: D001706:Biopsy; D002614:Chelating Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002675:Child, Preschool; D003300:Copper / Q000378:metabolism; D018450:Disease Progression; D004305:Dose-Response Relationship, Drug; D005260:Female; D005500:Follow-Up Studies; D006527:Hepatolenticular Degeneration / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism; D006801:Humans; D007089:Image Enhancement; D008099:Liver / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D010396:Penicillamine / Q000008:administration & dosage / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D002614:Chelating Agents; D003300:Copper; D010396:Penicillamine