Cancer chemoprevention from the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazol[4,5-b]pyridine: reconsideration of the evidence.
Paolini
M
M
Department of Pharmacology, University of Bologna, Italy. paolini@biocfarm.unibo.it
Biagi
G L
GL
Cantelli-Forti
G
G
D000818:Animals; D016588:Anticarcinogenic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001711:Biotransformation; D002273:Carcinogens / Q000493:pharmacokinetics / Q000633:toxicity*; D019363:Cytochrome P-450 CYP1A1 / Q000378:metabolism*; D019388:Cytochrome P-450 CYP1A2 / Q000378:metabolism*; D004224:Diterpenes / Q000494:pharmacology / Q000627:therapeutic use; D004790:Enzyme Induction / Q000187:drug effects; D005838:Genotype; D006358:Hot Temperature; D006801:Humans; D006900:Hydroxylation; D007093:Imidazoles / Q000037:antagonists & inhibitors* / Q000493:pharmacokinetics / Q000633:toxicity; D008658:Inactivation, Metabolic; D008297:Male; D008460:Meat; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology; D010084:Oxidation-Reduction; D008517:Phytotherapy; D051381:Rats; D011916:Rats, Inbred F344; D013662:Tea / Q000627:therapeutic use
D016588:Anticarcinogenic Agents; D002273:Carcinogens; D004224:Diterpenes; D007093:Imidazoles; D013662:Tea; C053401:kahweol; C049584:2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine; C053400:cafestol; D019363:Cytochrome P-450 CYP1A1; D019388:Cytochrome P-450 CYP1A2