Comprehensive school-based behavioral assessment of the effects of methylphenidate.
Individualized assessments of the effects of three doses of methylphenidate (MPH) were conducted for 2 students with attention deficit hyperactivity disorder within each child's classroom using behavioral, academic, and social measures. A double-blind, placebo-controlled, multielement design was used to evaluate the results. Results suggested that at least one or more dosages of MPH were associated with some degree of improvement for both children in each area of functioning as compared to placebo. However, the degree of improvement at times varied substantially across dosage and area of functioning. Results suggest that MPH dosage and area of child functioning are critical assessment parameters and that controlled clinical trials are necessary to optimize the effectiveness of treatment with MPH for the individual child.
Gulley
V
V
Department of Psychology, Louisiana State University, Baton Rouge 70803, USA.
Northup
J
J
D001289:Attention Deficit Disorder with Hyperactivity / Q000150:complications / Q000188:drug therapy*; D000697:Central Nervous System Stimulants / Q000627:therapeutic use*; D002648:Child; D002652:Child Behavior; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D006801:Humans; D007206:Individuality; D008137:Longitudinal Studies; D008297:Male; D008433:Mathematics; D008774:Methylphenidate / Q000627:therapeutic use*; D011932:Reading; D012919:Social Behavior; D013647:Task Performance and Analysis; D016896:Treatment Outcome
D000697:Central Nervous System Stimulants; D008774:Methylphenidate