title: Splanchnic mucosal ischemia: an unrecognized consequence of routine pneumoperitoneum.
abstract: The hemodynamic consequences of a pneumoperitoneum are well understood, but there have been no studies investigating its impact on splanchnic mucosal perfusion. By use of nasogastric tonometry, this study demonstrates that fit patients undergoing elective laparoscopic cholecystectomy at normal pneumoperitoneum pressures (12-15 mm Hg) develop significant splanchnic mucosal ischemia. This is a particular concern in patients with preexistent peripheral vascular disease undergoing prolonged laparoscopic procedures.
authors.affiliation: Department of Surgery, University of Auckland, Auckland Hospital, New Zealand.
authors.forename: M A
authors.initials: MA
authors.lastname: Windsor
authors.forename: M J
authors.initials: MJ
authors.lastname: Bonham
authors.forename: M
authors.initials: M
authors.lastname: Rumball
mesh_terms: D000328:Adult; D000368:Aged; D017081:Cholecystectomy, Laparoscopic; D002764:Cholecystitis / Q000601:surgery; D002908:Chronic Disease; D017558:Elective Surgical Procedures; D005260:Female; D006801:Humans; D007511:Ischemia / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D009092:Mucous Membrane; D011028:Pneumoperitoneum, Artificial / Q000009:adverse effects*; D011312:Pressure; D013152:Splanchnic Circulation