title: Neonatal TSH screening--an instrument of iodine supplementation monitoring in Bulgaria in comparison to Berlin--a preliminary report.
abstract: The challenge to eradicate iodine deficiency disorders (IDD) by the year 2000 worldwide will have positive consequences for more than 20 million people suffering from IDD. This is the main and common goal for the developing but also for a lot the developed countries. Sensitive tools like neonatal thyroid screening (NTS) can be used in order to make changes in iodine supplementation more transparent and to have a dynamic target oriented approach. The comparison between six districts in Bulgaria and Berlin revealed despite of some positive changes after the fortification of the iodine supplementation program still existing iodine deficiency in Bulgaria which is more profound than in Berlin in 1990. The shift to higher TSH-values in the Black-Sea region, classified by goitre-prevalence in 1956 as non-endemic for iodine deficiency, needs further investigation. Besides of iodine deficiency an influence of iodine-containing disinfectants and/or goitrogens is possible.
authors.affiliation: Department of Endocrinology and Diabetes, University Children's Hospital Sofia, Bulgaria.
authors.forename: I
authors.initials: I
authors.lastname: Stoeva
authors.forename: L
authors.initials: L
authors.lastname: Peneva
authors.forename: R
authors.initials: R
authors.lastname: Grigorova
authors.forename: B
authors.initials: B
authors.lastname: Vassileva
authors.forename: H
authors.initials: H
authors.lastname: Brumm
authors.forename: A
authors.initials: A
authors.lastname: Grüters
mesh_terms: D001604:Berlin; D002031:Bulgaria; D019353:Endemic Diseases; D006042:Goiter / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D007231:Infant, Newborn; D007455:Iodine / Q000008:administration & dosage* / Q000172:deficiency; D015997:Neonatal Screening; D013972:Thyrotropin / Q000097:blood*
chemical_list: D013972:Thyrotropin; D007455:Iodine