A retinoic acid receptor-alpha (RAR alpha) selective agonist modulates procoagulant activity of acute promyelocytic cells and induces their differentiation into neutrophils.
Shibakura
M
M
Koyama
T
T
Ohsawa
M
M
Kamiyama
R
R
Hirosawa
S
S
D000970:Antineoplastic Agents / Q000494:pharmacology*; D001565:Benzoates / Q000494:pharmacology*; D001777:Blood Coagulation / Q000187:drug effects*; D002454:Cell Differentiation / Q000187:drug effects; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000378:metabolism / Q000473:pathology*; D009504:Neutrophils / Q000473:pathology*; D018168:Receptors, Retinoic Acid / Q000819:agonists* / Q000378:metabolism*; D000072482:Retinoic Acid Receptor alpha; D013764:Tetrahydronaphthalenes / Q000494:pharmacology*
D000970:Antineoplastic Agents; D001565:Benzoates; C000607071:RARA protein, human; D018168:Receptors, Retinoic Acid; D000072482:Retinoic Acid Receptor alpha; D013764:Tetrahydronaphthalenes; C068073:Am 580