title: Radiation dosimetry for indium-111-pentetreotide.
abstract: We present radiation dose estimates for 111In-pentetreotide.
  
  
  METHODS
  Kinetic data were gathered in 10 subjects at two different sites. A compartmental model was used to fit the data, including retention, in three major organs and excretion.
  
  
  RESULTS
  The data were consistent for the subjects at both sites. The organ receiving the highest dose was the kidneys (0.52 mGy/MBq); the effective dose equivalent was 0.1 mSv/MBq, and the effective dose was 0.073 mSv/MBq.
  
  
  CONCLUSIONS
  The results of this study provide the basis for evaluation of radiation safety of this drug.
authors.affiliation: Oak Ridge Institute for Science and Education, Tennessee 37831-0117, USA.
authors.forename: M G
authors.initials: MG
authors.lastname: Stabin
authors.forename: P P
authors.initials: PP
authors.lastname: Kooij
authors.forename: W H
authors.initials: WH
authors.lastname: Bakker
authors.forename: T
authors.initials: T
authors.lastname: Inoue
authors.forename: K
authors.initials: K
authors.lastname: Endo
authors.forename: J
authors.initials: J
authors.lastname: Coveney
authors.forename: R
authors.initials: R
authors.lastname: de Jong
authors.forename: A
authors.initials: A
authors.lastname: Minegishi
mesh_terms: D000328:Adult; D002648:Child; D003198:Computer Simulation; D005260:Female; D006801:Humans; D007205:Indium Radioisotopes / Q000493:pharmacokinetics; D007668:Kidney / Q000528:radiation effects; D008297:Male; D015282:Octreotide / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D004369:Pentetic Acid / Q000031:analogs & derivatives* / Q000493:pharmacokinetics; D011247:Pregnancy; D011829:Radiation Dosage; D011835:Radiation Protection; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D014018:Tissue Distribution; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D007205:Indium Radioisotopes; D019275:Radiopharmaceuticals; C071632:SDZ 215-811; D004369:Pentetic Acid; D015282:Octreotide