Quantitative histomorphometric description of implant anchorage for three types of dental implants following 3 months of healing in baboons.
Important to the understanding of the dynamics associated with dental implant anchorage over time is a knowledge of the supporting anatomy for common endosseous implants prior to being placed into function. This study followed 20 screw-shaped dental implants placed in edentulated (2 months' healing time) posterior jaws of five adult female baboons. Implants made of three biomaterials were placed and allowed to heal for 3 months prior to processing for evaluation. Percentage integration and bone area data from six horizontal sections along the entire length of each implant were collected and analyzed for differences between jaws, implant biomaterials, jaw/biomaterial, and sections of the implants (ANOVA, pairwise comparison using LSM with Bonferroni adjustment). The results indicated that overall mean percentage integration was 46.5 and mean percentage bone area was 39.9. Maxillary and mandibular differences for both parameters were statistically different (integration: maxillary = 38.1%, mandibular = 56.7%; bone area: maxillary = 35.8%, mandibular = 44.9%; both were significant at the P < .05 level). The biomaterial analyses revealed significant differences for percentage integration between the metal implants and the hydroxyapatite-coated implant (commercially pure titanium = 39.1%, titanium-aluminum-vanadium = 40.0%, hydroxyapatite-coated = 61.5%), but no such difference was noted for percentage bone area (commercially pure titanium = 38.8%, titanium-aluminum-vanadium = 38.9%, hydroxyapatite-coated = 42.3%). Discussion of the relative importance of the two parameters highlights the fact that resistance to functional loads requires establishing and then maintaining an adequate volume of bone, which may have a functionally specific structure based on the mechanical properties of the local jaw environment.
Carr
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AB
Ohio State University, College of Dentistry, Columbus 43210-1241, USA.
Gerard
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DA
Larsen
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PE
D000497:Alloys; D000704:Analysis of Variance; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry; D003722:Dental Alloys / Q000737:chemistry; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D017267:Dental Prosthesis Design; D017886:Durapatite / Q000737:chemistry; D005260:Female; D005500:Follow-Up Studies; D007575:Jaw, Edentulous / Q000473:pathology / Q000601:surgery; D008334:Mandible / Q000473:pathology* / Q000601:surgery; D008437:Maxilla / Q000473:pathology* / Q000601:surgery; D016348:Osseointegration; D010215:Papio; D013314:Stress, Mechanical; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry; D014945:Wound Healing
D000497:Alloys; D001672:Biocompatible Materials; D003722:Dental Alloys; D015921:Dental Implants; C031462:titanium alloy (TiAl6V4); D017886:Durapatite; D014025:Titanium