title: Persistent pulmonary hemorrhage as the sole initial clinical manifestation of pediatric systemic lupus erythematosus.
abstract: Pulmonary hemorrhage (PH) is a rare but potentially life-threatening manifestation of systemic lupus erythematosus (SLE). In this report we describe a 13 year old girl with PH as the sole presenting clinical manifestation of her SLE. Her serology was diagnostic of SLE and one year after presentation she developed arthritis. She had a rapid serologic but delayed clinical response to combination therapy of intravenous pulse methylprednisolone, pulse cyclophosphamide and daily prednisone. Awareness of the possibility of pulmonary hemorrhage as a presentation of SLE may aid in the diagnosis and early, aggressive management of this condition.
authors.affiliation: Department of Pediatrics, Hospital for Sick Children, University of Toronto, Canada.
authors.forename: Y
authors.initials: Y
authors.lastname: Uziel
authors.forename: R M
authors.initials: RM
authors.lastname: Laxer
authors.forename: E D
authors.initials: ED
authors.lastname: Silverman
mesh_terms: D000293:Adolescent; D005260:Female; D006469:Hemoptysis / Q000000981:diagnostic imaging* / Q000209:etiology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000000981:diagnostic imaging*; D011859:Radiography