title: High-intensity lesion on T1-weighted MR images in neurofibromatosis type 1: a case of premalignant lesion.
abstract: We report a patient with NF1, who was followed up because of an optic glioma and one enhancing lesion presumed to be a pilocytic astrocytoma. T1- and T2-weighted MR images showed also a hyperintense periventricular lesion with no enhancement and no mass effect, of an unsuspected nature. Three years later a glioblastoma multiforme developed at the site of this preceding lesion.
authors.affiliation: Department of Neuroradiology Charcot, Salpêtrière Hospital, Paris, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Miaux
authors.forename: A
authors.initials: A
authors.lastname: Guermazi
authors.forename: P
authors.initials: P
authors.lastname: Cornu
authors.forename: K
authors.initials: K
authors.lastname: Mokhtari
authors.forename: B
authors.initials: B
authors.lastname: Singer
authors.forename: J
authors.initials: J
authors.lastname: Chiras
authors.forename: C
authors.initials: C
authors.lastname: Blanchet-Bardon
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000175:diagnosis*; D005260:Female; D005909:Glioblastoma / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D009456:Neurofibromatosis 1 / Q000175:diagnosis*; D011230:Precancerous Conditions / Q000175:diagnosis*