title: [HPLC of oligodeoxyribonucleoside phosphorothioates ].
abstract: Conditions are described for the separation of synthetic oligodeoxyribonucleoside phosphorothioates by HPLC using a SCOUT WP PEI weak anion exchanger and for the separation of oligodeoxyribonucleotides with mixed phosphate and phosphorothioate internucleotide bonds on a Partisphere C18 support in ion-pair conditions. The influence of the nucleoside composition and the number of phosphorothioate bonds on the retention time was studied.
authors.forename: V N
authors.initials: VN
authors.lastname: Metelev
authors.forename: V N
authors.initials: VN
authors.lastname: Tashlitskił
authors.forename: S
authors.initials: S
authors.lastname: Agraval
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D007475:Ion Exchange Resins; D009838:Oligodeoxyribonucleotides / Q000737:chemistry / Q000302:isolation & purification*; D013872:Thionucleosides / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D007475:Ion Exchange Resins; D009838:Oligodeoxyribonucleotides; D013872:Thionucleosides