title: Primary Sjögren's syndrome associated with hyaline-vascular type of Castleman's disease and autoimmune idiopathic thrombocytopenia.
abstract: We describe a case of primary Sjögren's syndrome complicated by hyaline-vascular type of Castleman's disease and autoimmune idiopathic thrombocytopenia. This type of Castleman's disease was diagnosed by biopsy of a right axillary lymph node 7 years after the onset of Sjögren's syndrome. The specimen showed small hyaline-vascular lymphoid follicles and interfollicular capillary proliferation. Serum IL-6 was slightly increased, but systemic manifestations, such as fever or weight loss, were not present. Hyaline-vascular type of Castleman's disease should be considered a lymphoproliferative disorder associated with Sjögren's syndrome.
authors.affiliation: National Defense Medical College, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Higashi
authors.forename: Y
authors.initials: Y
authors.lastname: Matsuki
authors.forename: T
authors.initials: T
authors.lastname: Hidaka
authors.forename: S
authors.initials: S
authors.lastname: Aida
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
authors.forename: H
authors.initials: H
authors.lastname: Nakamura
mesh_terms: D001706:Biopsy; D005871:Castleman Disease / Q000150:complications*; D005260:Female; D006801:Humans; D006818:Hyalin; D008198:Lymph Nodes / Q000473:pathology; D008875:Middle Aged; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications*; D012859:Sjogren's Syndrome / Q000150:complications*