Fibromuscular proliferation in finger arteries after hand replantation: a case report.
We report on a case where a digit of a previously replanted hand was amputated 3 years after injury. Histologically, the finger arteries demonstrated a marked intimal thickening due to fibromuscular proliferation, with narrowing of the lumen. The media showed muscular hyperplasia and fibrosis, whereas the adventitia was normal. These changes are probably a consequence of ischemia and reperfusion injury and might explain the persistent vasomotor insufficiency found in replantation patients.
Meuli-Simmen
C
C
Division of Reconstructive Surgery, University Hospital, Zurich, Switzerland.
Eiman
T
T
Alpert
B S
BS
Meyer
V E
VE
Buncke
G M
GM
Buncke
H J
HJ
D000328:Adult; D000671:Amputation, Surgical; D000673:Amputation, Traumatic / Q000601:surgery*; D001158:Arteries / Q000473:pathology; D002455:Cell Division; D005385:Fingers / Q000098:blood supply* / Q000601:surgery; D006230:Hand Injuries / Q000601:surgery*; D006801:Humans; D008297:Male; D008866:Microsurgery; D015427:Reperfusion Injury / Q000473:pathology; D012092:Replantation; D017539:Tunica Intima / Q000473:pathology