[Hemostasis using vasopressin analogs during conization of the uterine cervix and minor vaginal operations].
Peroperative haemorrhage is a frequent complication of conization of the portio uteri by surgery-by a "cold knife" scalpel or another method (LEEP, laser, etc.). In a clinical study comprising 41 patients with the diagnosis CIN I-III or laceration of the portio uteri classical conization by means of a scalpel was made with concurrent haemostasis with terlipressin (TLP) by paracervical administration (400 micrograms-REMESTYP 2 amp.). Concurrently the blood loss in ml was followed, the Hb level and other effects of the preparation. From the results ensues that side-effects after local administration of TLP were observed only in 12.2%. Peroperative blood losses were on average under 15 ml. Local paracervical TLP administration appears effective from the clinical aspect with regard to the low frequency of side-effects and the favourable haemostatic effect.
Jelínek
J
J
II. gynek.-porod. klinika LF MU, Brno.
Huvar
I
I
Roztocil
A
A
Pilka
L
L
D016063:Blood Loss, Surgical / Q000517:prevention & control*; D002584:Cervix Uteri / Q000601:surgery*; D019092:Conization; D005260:Female; D006488:Hemostasis, Surgical; D006801:Humans; D008236:Lypressin / Q000008:administration & dosage / Q000031:analogs & derivatives*; D000077585:Terlipressin; D002583:Uterine Cervical Neoplasms / Q000601:surgery; D014621:Vagina / Q000601:surgery*; D002578:Uterine Cervical Dysplasia / Q000601:surgery
D008236:Lypressin; D000077585:Terlipressin