title: Mutagenicity of 4-nitroquinoline n-oxide after its complexation with copper (II) 2-chlorophenoxyacetate.
abstract: Using the AMes test with Salmonella typhimurium strains TA97, TA100 and TA102, it was found that the mutagenicity of 4-nitroquinoline-N-oxide was much lower than that of the tetrakis[mu-2-chlorophenoxyacetato(1-)-O,O[bis(4-nitro-quinoline- N-oxide-O)dicopper(II) complex.
authors.affiliation: Department of Chemical Theory of Drugs, Faculty of Pharmacy, Comenius University, Bratislava, Slovakia.
authors.forename: M
authors.initials: M
authors.lastname: Blahová
authors.forename: N
authors.initials: N
authors.lastname: Lahitová
authors.forename: J
authors.initials: J
authors.lastname: Sokolík
mesh_terms: D015112:4-Nitroquinoline-1-oxide / Q000494:pharmacology; D000818:Animals; D051379:Mice; D008810:Mice, Inbred C57BL; D008862:Microsomes, Liver / Q000378:metabolism; D009152:Mutagenicity Tests; D009153:Mutagens / Q000494:pharmacology*; D009942:Organometallic Compounds / Q000737:chemistry / Q000494:pharmacology*; D012486:Salmonella typhimurium / Q000187:drug effects*
chemical_list: D009153:Mutagens; D009942:Organometallic Compounds; C111018:tetrakis(mu-2-chlorophenoxyacetato(1-)-O,O')bis(4-nitroquinoline N-oxide-O)dicopper(II); D015112:4-Nitroquinoline-1-oxide