Incidence and persistence of anti-Kell after transfusion of Kell-positive blood.
116 Kell-negative patients who had received at least one Kell-positive blood unit were tested about 3 and 12 months after transfusion. Antibody screening was performed by tube test and by gel centrifugation; both methods yielded identical results. After 3 months, anti-Kell was detected in 11 (9.5%) patients. Antibody titers using K+, k+ cells ranged from 1:1 to 1:128 with a predominance of low titers. Titers using K+, k- cells tended to be higher by one step; one anti-Kell could only be demonstrated with K+, k- cells. After about 12 months, anti-Kell could no longer be detected in 5 of the 11 patients (45.5%).
Schabel
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A
Institut für Transfusionsmedizin, Katharinenhospital, Stuttgart, Germany.
König
A L
AL
Schiebel
M R
MR
Sugg
U
U
D001803:Blood Transfusion; D005500:Follow-Up Studies; D006801:Humans; D007518:Isoantibodies / Q000097:blood*; D007626:Kell Blood-Group System / Q000276:immunology*; D008875:Middle Aged; D013997:Time Factors
D007518:Isoantibodies; D007626:Kell Blood-Group System