Bilateral multifocal retinal arteriolar sheathing as the only ocular finding in hereditary amyloidosis.
OBJECTIVE
To report the early ocular findings in hereditary amyloidosis.


METHODS
Case report of a visually asymptomatic, 52-year-old Mexican man with systemic manifestations of amyloidosis (peripheral neuropathy, restrictive cardiomyopathy), with a positive family history, and with amyloid on an endomyocardial biopsy specimen, who had bilateral multifocal sheathing or cuffing of the peripheral retinal arterioles.


RESULTS
An extensive evaluation for retinal vasculitis was discontinued when hereditary amyloidosis was diagnosed.


CONCLUSIONS
Focal retinal periarteriolar plaques of amyloid may be the earliest and only ocular finding of hereditary amyloidosis.
Noble
K G
KG
Department of Ophthalmology, New York University Medical Center, NY 10016, USA.
D000682:Amyloid / Q000378:metabolism; D000686:Amyloidosis / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D001160:Arterioles / Q000473:pathology; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D012161:Retinal Artery / Q000473:pathology*; D012164:Retinal Diseases / Q000235:genetics / Q000473:pathology
D000682:Amyloid