title: Sydenham's chorea.
abstract: Sydenham's chorea (SC) is a disorder of the central nervous system (CNS) characterized by sudden, involuntary, arrhythmic, clonic, and purposeless movements. SC appears to provide a model for understanding various neuropsychiatric dysfunctions. Its relationship with attentional deficits, obsessive-compulsive symptoms (OCS) as well as movement disorders provides support for the hypothesis of the involvement of the corticostriatal loops in the pathophysiology of the disorder.
authors.affiliation: Pediatric Department, São Paulo University Medical School, Brazil.
authors.forename: M J
authors.initials: MJ
authors.lastname: Marques-Dias
authors.forename: M T
authors.initials: MT
authors.lastname: Mercadante
authors.forename: D
authors.initials: D
authors.lastname: Tucker
authors.forename: P
authors.initials: P
authors.lastname: Lombroso
mesh_terms: D001327:Autoimmune Diseases / Q000209:etiology; D001479:Basal Ganglia / Q000503:physiopathology; D001526:Behavioral Symptoms; D002819:Chorea / Q000188:drug therapy / Q000453:epidemiology / Q000209:etiology / Q000276:immunology / Q000503:physiopathology; D006801:Humans; D007175:Impulsive Behavior / Q000503:physiopathology; D012213:Rheumatic Fever / Q000150:complications / Q000453:epidemiology / Q000235:genetics