[Determination of the potential doubling time of tumors using bromodeoxyuridine and flow cytometry].
Tumor growth-rate affects prognosis and treatment planning. The injection of bromodeoxyuridine in dogs and cats permits determination of the potential doubling time following a biopsy of neoplastic tissue and flow cytometric analysis. The essentially non-invasive method gives exact results within 24 hours. This report describes a method to measure potential tumor doubling time of different tumors, and presents results of canine and feline tumors.
Schwyn
U
U
Veterinär-medizinisches Departement, Universität Zürich.
Kaser-Hotz
B
B
Hauser
B
B
Fodor
G
G
Ruckstuhl
H
H
Crompton
N E
NE
D000818:Animals; D000964:Antimetabolites, Antineoplastic; D001706:Biopsy / Q000662:veterinary; D001973:Bromodeoxyuridine; D002371:Cat Diseases / Q000473:pathology*; D002415:Cats; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D005434:Flow Cytometry / Q000662:veterinary; D009369:Neoplasms / Q000473:pathology / Q000662:veterinary*; D011379:Prognosis; D013997:Time Factors
D000964:Antimetabolites, Antineoplastic; D001973:Bromodeoxyuridine