Persistent pulmonary hemorrhage as the sole initial clinical manifestation of pediatric systemic lupus erythematosus.
Pulmonary hemorrhage (PH) is a rare but potentially life-threatening manifestation of systemic lupus erythematosus (SLE). In this report we describe a 13 year old girl with PH as the sole presenting clinical manifestation of her SLE. Her serology was diagnostic of SLE and one year after presentation she developed arthritis. She had a rapid serologic but delayed clinical response to combination therapy of intravenous pulse methylprednisolone, pulse cyclophosphamide and daily prednisone. Awareness of the possibility of pulmonary hemorrhage as a presentation of SLE may aid in the diagnosis and early, aggressive management of this condition.
Uziel
Y
Y
Department of Pediatrics, Hospital for Sick Children, University of Toronto, Canada.
Laxer
R M
RM
Silverman
E D
ED
D000293:Adolescent; D005260:Female; D006469:Hemoptysis / Q000000981:diagnostic imaging* / Q000209:etiology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000000981:diagnostic imaging*; D011859:Radiography