[Prognostic factors of microalbuminuria in diabetes mellitus type 1].
The prophylaxis in diabetic nephropathy begin with the knowledge of factors that affect on the microalbuminuria. We designed a retrospective study with a follow-up of 8.4 +/- 2.9 years, in 75 patients with diabetes mellitus type 1: group A (n = 34) with microalbuminuria: group B (n = 41) without microalbuminuria. We tried to know the factors related to the on set of albuminuria. The mean Hb A1c was: Group A 8.7 +/- 1.5%; Group B 8.1 +/- 1% (p < 0.02). Patients that actually have microalbuminuria presented several years before a blood pressure (TA) greater than the group without microalbuminuria (Group A: TA systolic [TAS] 124.5 +/- 13 versus Group B 110.6 +/- 1 mmHg; p < 0.0001); (Group A: TA diastolic [TAD] 69.2 +/- 7 versus Group B 66.6 +/- 6 mm Hg; p < 0.0001). We confirm the influence of metabolic control on the microalbuminuria's beginning and the arterial blood pressure is greater in the group of patients with microalbuminuria actually.
García Fernández
Y
Y
Servicio de Endocrinología, Hospital de Cruces, Baracaldo, Vizcaya.
Goicolea Opacua
I
I
Vicente Vicente
M A
MA
Vázquez García
J A
JA
D000328:Adult; D000419:Albuminuria / Q000175:diagnosis* / Q000503:physiopathology; D000704:Analysis of Variance; D001794:Blood Pressure; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis / Q000503:physiopathology / Q000652:urine*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012044:Regression Analysis; D012189:Retrospective Studies; D013997:Time Factors