Pheochromocytoma in pregnancy manifesting hypertensive crisis induced by metoclopramide.
Pheochromocytoma is a rare disease that may occur during pregnancy. Antenatal diagnosis is essential to improve fetal and maternal mortality and morbidity, but is difficult. A hypertensive crisis was induced by metoclopramide, a widely used anti-emetic, in a pregnant normotensive woman. Biochemical measurements of plasma and urine catecholamines and magnetic resonance imaging (MRI) established the diagnosis of pheochromocytoma. She was medically treated with prazocin and electively delivered by cesarean section simultaneously with tumor resection.
Takai
Y
Y
Department of Obstetrics and Gynecology, Saitama Medical Center, Kawagoe, Japan. yastakai-tky@umin.ac.jp
Seki
H
H
Kinoshita
K
K
D000310:Adrenal Gland Neoplasms / Q000175:diagnosis* / Q000628:therapy; D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use; D000328:Adult; D000932:Antiemetics / Q000009:adverse effects; D005260:Female; D006801:Humans; D006973:Hypertension / Q000139:chemically induced; D008279:Magnetic Resonance Imaging; D008787:Metoclopramide / Q000009:adverse effects; D010673:Pheochromocytoma / Q000175:diagnosis* / Q000628:therapy; D011224:Prazosin / Q000627:therapeutic use; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000175:diagnosis* / Q000628:therapy
D000317:Adrenergic alpha-Antagonists; D000932:Antiemetics; D008787:Metoclopramide; D011224:Prazosin