[Staphylococcal sepsis associated with platelet transfusion: report of a new case and review of the literature].
Bacterial contamination of blood components is an infrequent although potentially fatal event. Bacterial contamination rate of platelet concentrates (PC) varies between 1/900 to 1/2,000 random donor units. However the risk of symptomatic bacteriemias is lower (between 1/2,000 to 1/12,000 random donor units). The organisms most commonly implicated in contaminated PC are gram-positive bacteria such as coagulase negative Staphylococci, Bacillus cereus or Propionibacterium acnes, although gram-negative organisms are also found that generally are associated to a higher mortality. Here, a fatal case of sepsis due to Staphylococcus carnosus associated to transfusion of a contaminated random donor platelet unit is reported.
Cid
J
J
Servicio de Hemoterapia, Hospital Clínic i Provincial de Barcelona.
Lozano
M
M
Nomdedeu
B
B
Mazzara
R
R
Vila
J
J
Rives
S
S
Ordinas
A
A
D016470:Bacteremia / Q000097:blood / Q000453:epidemiology / Q000635:transmission*; D001752:Blast Crisis / Q000473:pathology / Q000628:therapy; D017809:Fatal Outcome; D006801:Humans; D015994:Incidence; D015477:Leukemia, Myelomonocytic, Chronic / Q000473:pathology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009102:Multiple Organ Failure / Q000209:etiology; D017713:Platelet Transfusion / Q000009:adverse effects*; D012772:Shock, Septic / Q000209:etiology*; D013030:Spain / Q000453:epidemiology; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission*; D013210:Staphylococcus / Q000302:isolation & purification; D014481:United States / Q000453:epidemiology