Preliminary data on the efficacy of a Giardia vaccine in puppies.
Twenty puppies were vaccinated with a trophozoite-derived Giardia vaccine on day 0 and boosted on day 21 (Group 1); 10 control puppies received only saline (Group 2). Both groups were experimentally infected on day 35 with 1 x 10(6) Giardia duodenalis trophozoites by intraduodenal injection. Immunization provided protection to experimental Giardia infection.
Olson
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ME
Animal Health Unit, University of Calgary, Alberta.
Morck
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DW
Ceri
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H
D000704:Analysis of Variance; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood / Q000276:immunology; D004283:Dog Diseases / Q000276:immunology / Q000503:physiopathology / Q000517:prevention & control*; D004285:Dogs; D005243:Feces / Q000469:parasitology; D005260:Female; D005872:Giardia / Q000276:immunology* / Q000302:isolation & purification; D005873:Giardiasis / Q000503:physiopathology / Q000517:prevention & control / Q000662:veterinary*; D007070:Immunoglobulin A / Q000097:blood / Q000276:immunology; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology; D007075:Immunoglobulin M / Q000097:blood / Q000276:immunology; D007267:Injections / Q000379:methods / Q000662:veterinary; D008297:Male; D016052:Protozoan Vaccines / Q000008:administration & dosage / Q000276:immunology / Q000592:standards; D015430:Weight Gain / Q000502:physiology
D000913:Antibodies, Protozoan; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D016052:Protozoan Vaccines