title: Herpes simplex infection of the jejunum occurring in the early post-transplantation period.
abstract: Reactivation of infections with herpes viruses is a frequent and major cause of morbidity after bone marrow transplantation. In this case report we stress that HSV infections of the colon and small intestine should be considered in the differential diagnosis of diarrhea and intestinal bleeding in the early post-transplantation period. Severe acute GVHD and subsequent intensive immunosuppressive treatment may increase the risk for reactivation of HSV infection particularly in situations in which acyclovir prophylaxis has been omitted.
authors.affiliation: Abteilung für Innere Medizin und Poliklinik m.S. Hämatologie und Onkologie, Virchow Klinikum, Humboldt Universität, Berlin, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Kingreen
authors.forename: A
authors.initials: A
authors.lastname: Nitsche
authors.forename: J
authors.initials: J
authors.lastname: Beyer
authors.forename: W
authors.initials: W
authors.lastname: Siegert
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D016026:Bone Marrow Transplantation; D004279:DNA, Viral / Q000302:isolation & purification; D003937:Diagnosis, Differential; D004751:Enteritis / Q000150:complications / Q000821:virology; D017809:Fatal Outcome; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000150:complications* / Q000821:virology; D006086:Graft vs Host Disease / Q000150:complications*; D006561:Herpes Simplex / Q000150:complications / Q000175:diagnosis* / Q000209:etiology*; D006801:Humans; D007150:Immunohistochemistry; D007579:Jejunal Diseases / Q000150:complications / Q000209:etiology* / Q000821:virology; D008223:Lymphoma / Q000150:complications / Q000628:therapy; D016133:Polymerase Chain Reaction; D011241:Prednisone / Q000627:therapeutic use; D018139:Simplexvirus / Q000302:isolation & purification
chemical_list: D000893:Anti-Inflammatory Agents; D004279:DNA, Viral; D011241:Prednisone