title: [Transitional laryngeal papilloma: clinical aspects, diagnosis and treatment].
abstract: Basing on the results of long-term observational study of 200 patients with laryngeal papillomatosis the authors made a conclusion on cycle pattern of the disease course. Each cycle consists of two periods: active (rapid growth of the tumor) and passive (slow growth of the tumor, recurrences are rare, 1-3 years of remission). A case of a male patient is reported illustrating cycle course of transitional laryngeal papilloma. In the beginning of the third cycle, in active period, his papilloma underwent malignant transformation. Cryotherapy of papilloma is thought ineffective.
authors.affiliation: Kafedra otorinolaringologii Rossiĭskogo universiteta druzhby narodov.
authors.forename: V F
authors.initials: VF
authors.lastname: Antoniv
authors.forename: N A
authors.initials: NA
authors.lastname: Lusinian
authors.forename: T Ia
authors.initials: TIa
authors.lastname: Vasyliv
authors.forename: M O
authors.initials: MO
authors.lastname: Panasiuk
authors.forename: V M
authors.initials: VM
authors.lastname: Aksenov
mesh_terms: D000293:Adolescent; D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002648:Child; D003131:Combined Modality Therapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery*; D007825:Laryngectomy; D008297:Male; D009824:Ointments; D010212:Papilloma / Q000188:drug therapy* / Q000601:surgery*; D011447:Prospidium / Q000627:therapeutic use*; D012075:Remission, Spontaneous; D014833:Voice Quality
chemical_list: D000970:Antineoplastic Agents; D009824:Ointments; D011447:Prospidium