title: [Carcinoma of the bladder: experience of the USC Los Angeles (antireflux nipple according to Ghoneim)].
abstract: A pelvic lymph node dissection, using continent urinary diversion and lower urinary tract reconstruction can significantly improve the patient's quality of life After almost 25 years of experience in treating 930 patients with carcinoma of the bladder, the Author concludes that most patients with superficial bladder cancer (grade 1 or grade 2) can be managed conservatively. Patients in the Urology Department at University of Southern California, who had grade 3 T1 tumours showing a mutation of P53 received early aggressive therapy, namely, cystectomy. The probability of recurrence for such patients was just 14% and the survival rate among all 930 patients (including grades 1-3) was over 75%. Lower urinary tract reconstruction using the Kock neobladder was found to give highly functional results, with few complications and a high satisfaction rate among patients (62% very happy, 20% happy and 18% satisfied with the results).
authors.affiliation: Dipartimento di Urologia, Scuola di Medicina, University of Southern California (USC), Los Angeles, USA.
authors.forename: D G
authors.initials: DG
authors.lastname: Skinner
mesh_terms: D002295:Carcinoma, Transitional Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D009367:Neoplasm Staging; D010388:Pelvis; D011187:Posture; D012737:Sex Factors; D001743:Urinary Bladder / Q000601:surgery; D001749:Urinary Bladder Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D014547:Urinary Diversion / Q000379:methods*