title: Cardiopulmonary and anesthetic effects of propofol administered intraosseously to green iguanas.
abstract: OBJECTIVE
  To determine cardiopulmonary effects of intraosseous administration of propofol in green iguanas (Iguana iguana).
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  14 green iguanas.
  
  
  METHODS
  Anesthesia was induced in 4 iguanas with propofol (10 mg/kg [4.5 mg/lb] of body weight, intraosseously). Heart and respiratory rates, functional hemoglobin oxygen saturation (SpO2), end-tidal CO2 concentration, and cloacal temperature were recorded. Ten additional iguanas were given propofol intraosseously for induction (5 mg/kg [2.3 mg/lb] and maintenance (0.5 mg/kg/min [0.23 mg/lb/min], q 30 min) of anesthesia. Heart and respiratory rates, cloacal temperature, and SpO2 were recorded.
  
  
  RESULTS
  Mean induction time for the first 4 iguanas was 1.2 minutes. A significant decrease in heart rate was seen 1 minute after induction of anesthesia. All iguanas were apneic, but spontaneous ventilation resumed within 5 minutes. End-tidal CO2 concentration decreased from 46 mm of Hg 4 minutes after induction of anesthesia to 32 mm of Hg 30 minutes after induction of anesthesia. Mean duration of anesthesia was 27 minutes. Mean induction time for the other 10 iguanas was 3 minutes. A significant decrease in heart rate was detected 35 minutes after induction of anesthesia and persisted until 120 minutes. Mean SpO2 value decreased from 79% 5 minutes after induction of anesthesia to 64% 30 minutes after induction of anesthesia. Mean recovery time was 57 minutes.
  
  
  CONCLUSIONS
  Propofol is an effective anesthetic agent for use in green iguanas. It is recommended that iguanas be intubated, provided oxygen, and given assisted ventilation after administration of propofol to prevent hypoxemia and hypercapnia.
authors.affiliation: Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville 32610-0125, USA.
authors.forename: R A
authors.initials: RA
authors.lastname: Bennett
authors.forename: J
authors.initials: J
authors.lastname: Schumacher
authors.forename: K
authors.initials: K
authors.lastname: Hedjazi-Haring
authors.forename: S M
authors.initials: SM
authors.lastname: Newell
mesh_terms: D000758:Anesthesia / Q000379:methods / Q000662:veterinary*; D000777:Anesthetics / Q000008:administration & dosage / Q000494:pharmacology*; D000818:Animals; D002245:Carbon Dioxide / Q000097:blood; D006339:Heart Rate / Q000187:drug effects*; D007076:Iguanas / Q000502:physiology*; D017148:Infusions, Intraosseous / Q000662:veterinary; D010100:Oxygen / Q000097:blood; D015742:Propofol / Q000008:administration & dosage / Q000494:pharmacology*; D012119:Respiration / Q000187:drug effects*; D013977:Tibia
chemical_list: D000777:Anesthetics; D002245:Carbon Dioxide; D010100:Oxygen; D015742:Propofol