title: 99mTc MIBI in neurofibromatosis imaging diagnosis: case report.
abstract: 99mTc MIBI has been shown to accumulate in different cancer cells types, in vitro and malignant tumours in vivo, making evidence of the scintigraphic diagnostic of them. We report two cases of neurofibromatosis type I, which has realised high levels of 99mTc MIBI uptake, primary to all chemo- or radiotherapy. Only certain zones of tumorous localisation have been seen, but a relation with the lesion histology was not really established. In conclusion, 99mTc MIBI scintigraphy may be usefull in the investigation of type I neurofibromatosis.
authors.affiliation: Disciplina de Biofizică şi Medicina Nucleară, Facultatea de Medicină, U.M.F. Gr. T. Popa, Iaşi.
authors.forename: C
authors.initials: C
authors.lastname: Stefănescu
authors.forename: M
authors.initials: M
authors.lastname: Meignan
authors.forename: P
authors.initials: P
authors.lastname: Volkenstein
authors.forename: V
authors.initials: V
authors.lastname: Rusu
mesh_terms: D000293:Adolescent; D000328:Adult; D001132:Arm; D001706:Biopsy; D005153:Facial Neoplasms / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D009456:Neurofibromatosis 1 / Q000000981:diagnostic imaging*; D018319:Neurofibrosarcoma / Q000000981:diagnostic imaging / Q000473:pathology; D011877:Radionuclide Imaging; D012878:Skin Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D017256:Technetium Tc 99m Sestamibi; D013848:Thigh
chemical_list: D017256:Technetium Tc 99m Sestamibi