title: Factor V Leiden mutation in a case with ischemic stroke: which relationship? A case report.
abstract: A 50-year-old man presented spontaneous internal carotid artery dissection with ischemic stroke. He had a history of deep venous thrombosis, and an activated protein C resistance due to factor V Leiden mutation was documented. He showed no other vascular risk factor. This unusual case puts the question whether this coagulation defect may be related to the stroke occurrence.
authors.affiliation: Department of Neurosciences, University of Pisa, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Orlandi
authors.forename: A
authors.initials: A
authors.lastname: Pellegrinetti
authors.forename: C
authors.initials: C
authors.lastname: Fioretti
authors.forename: A
authors.initials: A
authors.lastname: Martini
authors.forename: L
authors.initials: L
authors.lastname: Murri
mesh_terms: D000784:Aortic Dissection / Q000209:etiology; D000925:Anticoagulants / Q000627:therapeutic use; D002545:Brain Ischemia / Q000209:etiology*; D002343:Carotid Artery, Internal; D016893:Carotid Stenosis / Q000209:etiology; D002561:Cerebrovascular Disorders / Q000209:etiology; D005165:Factor V / Q000235:genetics*; D005500:Follow-Up Studies; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D017354:Point Mutation / Q000235:genetics*; D011486:Protein C; D013924:Thrombophlebitis / Q000188:drug therapy / Q000209:etiology; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D011486:Protein C; C095381:factor V Leiden; D014859:Warfarin; D005165:Factor V; D006493:Heparin