Release of stored retinol from adipocytes.
Adipose tissue is second only to liver as a retinol depot. Retinol is stored there is part as retinyl esters. In cultured mouse adipocytes, a hormone-sensitive lipase hydrolyzes these esters upon cAMP stimulation, with free retinol being released into the medium.
Wolf
G
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Department of Nutritional Sciences, University of California, Berkeley 94720-3104, USA.
D017667:Adipocytes / Q000187:drug effects / Q000378:metabolism*; D000818:Animals; D003994:Bucladesine / Q000494:pharmacology; D002478:Cells, Cultured; D000242:Cyclic AMP / Q000502:physiology*; D004952:Esters; D051379:Mice; D014801:Vitamin A / Q000378:metabolism*
D004952:Esters; D014801:Vitamin A; D003994:Bucladesine; D000242:Cyclic AMP