title: Incidence and spectrum of spontaneous neoplasms in Han:NMRI mice of both sexes.
abstract: Two hundred Han:NMRI mice of both sexes were kept for their natural life-span to obtain information about the spontaneous tumour spectrum of this strain. Neoplasms were seen in 72% of the males and 64% of the females. Lung tumours, Harderian gland tumours, liver and adrenal gland neoplasms were common in males, while ovary tumours and lung tumours were the most frequent neoplasms in females.
authors.affiliation: Fraunhofer Institute of Toxicology and Aerosol Research, Department of Pathology, Hannover, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Rittinghausen
authors.forename: J
authors.initials: J
authors.lastname: Kaspareit
authors.forename: U
authors.initials: U
authors.lastname: Mohr
mesh_terms: D000367:Age Factors; D000818:Animals; D005260:Female; D015994:Incidence; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009369:Neoplasms / Q000453:epidemiology* / Q000473:pathology* / Q000662:veterinary; D012376:Rodent Diseases / Q000453:epidemiology* / Q000473:pathology*; D012737:Sex Factors