title: Characterization of the genes for mouse LERK-3/Ephrin-A3 (Epl3), mouse LERK-4/Ephrin-A4 (Epl4), and human LERK-6/Ephrin-A2 (EPLG6): conservation of intron/exon structure.
abstract: We have isolated the genes for the eph receptor family ligands mouse LERK-3/Ephrin-A3 (Epl3), mouse LERK-4/Ephrin-A4 (Epl4), and human LERK-6/Ephrin-A2 (EPLG6). These genes show a high level of conservation in their intron/exon structures encoding the receptor-binding region. In addition, the nucleotide sequences of the genes reveal the predicted cDNA sequence of mouse LERK-3/Ephrin-A3, mouse LERK-4/Ephrin-A4, and human LERK-6/Ephrin-A2.
authors.affiliation: Department of Molecular Biology, Immunex Corporation, Seattle, Washington 98101, USA. cerretti@immunex.com
authors.forename: D P
authors.initials: DP
authors.lastname: Cerretti
authors.forename: N
authors.initials: N
authors.lastname: Nelson
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D003001:Cloning, Molecular; D017124:Conserved Sequence; D036383:Ephrin-A2; D036384:Ephrin-A3; D036385:Ephrin-A4; D005091:Exons; D006801:Humans; D017403:In Situ Hybridization / Q000379:methods; D007438:Introns; D008565:Membrane Proteins / Q000235:genetics* / Q000378:metabolism; D051379:Mice; D008969:Molecular Sequence Data; D014176:Protein Biosynthesis; D015183:Restriction Mapping; D014157:Transcription Factors / Q000235:genetics* / Q000378:metabolism
chemical_list: D036383:Ephrin-A2; D036384:Ephrin-A3; D036385:Ephrin-A4; D008565:Membrane Proteins; D014157:Transcription Factors