title: [Comparison of HLA typing and retyping data in patients with bone marrow transplantation].
abstract: Comparing HLA data from 851 patients with serological HLA-A, -B, -DR and/or PCR-SSO HLA-DRB, -DQB reevaluated HLA types produced 107 (12.5%) different results. The high discrepancy of HLA data from patients confirm the demand for a serological HLA-A, -B and a DNA HLA-DRB, -DQB reevaluation before starting an unrelated donor search for bone marrow transplantation. The reliability of serological HLA-DRB, -DQB typing was evaluated as 97.8%, whereas DNA HLA-DRB, -DQB typing was 99.5%.
authors.affiliation: Abteilung Transplantationsimmunologie, DRK-Blutspendezentrale Ulm, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Wölpl
authors.forename: M
authors.initials: M
authors.lastname: Fischer
authors.forename: T
authors.initials: T
authors.lastname: Eiermann
authors.forename: S F
authors.initials: SF
authors.lastname: Goldmann
mesh_terms: D016026:Bone Marrow Transplantation / Q000276:immunology*; D015234:HLA-A Antigens / Q000276:immunology; D015235:HLA-B Antigens / Q000276:immunology; D015236:HLA-C Antigens / Q000276:immunology; D006683:HLA-DQ Antigens / Q000276:immunology; D006684:HLA-DR Antigens / Q000276:immunology; D006650:Histocompatibility Testing; D006801:Humans; D016133:Polymerase Chain Reaction / Q000379:methods
chemical_list: D015234:HLA-A Antigens; D015235:HLA-B Antigens; D015236:HLA-C Antigens; D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens
vernacular_title: Vergleich der HLA-Typisierungs- und Retypisierungsdaten bei Patienten mit Knochenmarktransplantation.