[Familial investigations of carriers of Rh 33].
The erythrocytes of a blood donor (P) showed an unusual pattern with anti-D sera: no agglutination with incomplete sera, and a strong agglutination with 2 out of 5 complete, monoclonal sera. These findings suggested the presence of an Rh 33, which was then confirmed in two external laboratories as the genotyp R0Har. Using anti-e sera, the titer scores of the cells of P were comparable with those of Ee cells but were only half as high as the scores of ee cells. This is consistent with a weak e in R0Har. The red cells of the donor's daughter (T) gave a positive reaction with all anti-D sera, but we observed no or only weak agglutination with several anti-e sera. It is very probable that T is also carrier of R0Har.
Endres
W
W
Blutbank-Immunhämatologie-Transfusionsmedizin, Medizinische Hochschule, Hannover, Deutschland.
Lichy
S
S
Stangel
W
W
D001782:Blood Donors; D001788:Blood Grouping and Crossmatching; D005260:Female; D006580:Genetic Carrier Screening; D006239:Haplotypes; D006386:Hemagglutination Tests; D006801:Humans; D008297:Male; D010375:Pedigree; D012204:Rh-Hr Blood-Group System / Q000235:genetics*
D012204:Rh-Hr Blood-Group System
Familienuntersuchung einer Trägerin von Rh 33.