title: Rapid termination of intraoperative stimulation-evoked seizures with application of cold Ringer's lactate to the cortex. Technical note.
abstract: One major risk of intraoperative stimulation mapping is the production of stimulation-evoked seizures. Cold Ringer's lactate solution was applied directly to the irritated cortex in 22 patients with stimulation-induced seizures that occurred during intraoperative brain mapping procedures. The irrigation rapidly and reliably terminated these simple partial seizures and eliminated the need for intravenously administered short-acting barbiturates with antiepileptic properties. The authors describe a practical and simple method for controlling stimulation-induced seizure activity during brain mapping procedures.
authors.affiliation: Indianapolis Neurosurgical Group, Incorporated, Indiana, USA.
authors.forename: C J
authors.initials: CJ
authors.lastname: Sartorius
authors.forename: M S
authors.initials: MS
authors.lastname: Berger
mesh_terms: D000287:Administration, Topical; D001931:Brain Mapping; D001932:Brain Neoplasms / Q000601:surgery*; D003080:Cold Temperature; D004558:Electric Stimulation / Q000009:adverse effects*; D006801:Humans; D007431:Intraoperative Complications / Q000188:drug therapy* / Q000209:etiology; D007432:Intraoperative Period; D007552:Isotonic Solutions / Q000627:therapeutic use*; D000077325:Ringer's Lactate; D012640:Seizures / Q000209:etiology*
chemical_list: D007552:Isotonic Solutions; D000077325:Ringer's Lactate