title: Can primary prevention or selective screening for melanoma be more precisely targeted through general practice? A prospective study to validate a self administered risk score.
abstract: OBJECTIVE
  To establish whether a questionnaire incorporating MacKie's risk factor flow chart can identify patients at high risk for melanoma so that they can be targeted for primary and secondary prevention. To validate the risk score derived from the questionnaire and test the feasibility of self completion by comparing patients' self reported skin characteristics with a skin examination performed by an experienced general practitioner.
  
  
  METHODS
  Prospective questionnaire survey followed by a comparative study.
  
  
  METHODS
  16 randomly selected group practices in a health district in Cheshire, United Kingdom.
  
  
  METHODS
  Questionnaire survey--3105 consecutive patients aged 16 years and over attending for a primary care consultation; comparative study--a self selected subsample of 388 of the 3,105 patients.
  
  
  METHODS
  MacKie risk group for melanoma. Comparison of high risk skin characteristics reported by patients and those noted during a skin examination by a doctor (kappa statistic).
  
  
  RESULTS
  4.3% of patients (87% women) were in the highest risk group and 4.4% (79% men) were in the second highest risk group, as defined by the MacKie score. Agreement between patients' self appraisal of skin characteristics and clinical skin examinations was reflected in kappa values of 0.67 for freckles, 0.60 for moles, and 0.43 for atypical naevi.
  
  
  CONCLUSIONS
  This questionnaire helped to identify a group at high risk for melanoma. Furthermore, good agreement was found when the patient's risk scores were compared with results of the clinical skin examination. This risk score is potentially useful in targeting primary and secondary prevention of melanoma through general practice.
authors.affiliation: Department of General Practice, Maelfa Health Centre, Llanedeyrn, Cardiff. 100131.1162@compuserve.com
authors.forename: A
authors.initials: A
authors.lastname: Jackson
authors.forename: C
authors.initials: C
authors.lastname: Wilkinson
authors.forename: M
authors.initials: M
authors.lastname: Ranger
authors.forename: R
authors.initials: R
authors.lastname: Pill
authors.forename: P
authors.initials: P
authors.lastname: August
mesh_terms: D017677:Age Distribution; D005194:Family Practice; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods / Q000458:organization & administration*; D008545:Melanoma / Q000517:prevention & control*; D011322:Primary Prevention / Q000379:methods / Q000458:organization & administration*; D011446:Prospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D017678:Sex Distribution; D012878:Skin Neoplasms / Q000517:prevention & control*; D006113:United Kingdom