title: Gastric perforation with Candida tropicalis invasion in a previously healthy girl.
abstract: Fungal cells were observed infiltrating the submucosal margins of an acutely perforated gastric ulceration in an apparently immunocompetent 3-year-old girl. Perforation had occurred 24 h after hospital admission because of pain and vomiting. Colonies of Candida tropicalis were grown from peritoneal fluid and blood cultures. After surgical repair and a 30-day treatment with amphotericin B at a daily dose of 1 mg kg-1 body weight, the child was discharged in good health. No further infections have occurred in the 3 years since treatment.
authors.affiliation: Laboratorio de Immunología y Reumatología, Hospital Infantil de México Federico Gómez, México City, México.
authors.forename: M A
authors.initials: MA
authors.lastname: Faure-Fontenla
authors.forename: E
authors.initials: E
authors.lastname: Bracho-Blanchet
authors.forename: C
authors.initials: C
authors.lastname: Yañez-Molina
authors.forename: L
authors.initials: L
authors.lastname: Barragan-Tame
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000150:complications* / Q000628:therapy; D002675:Child, Preschool; D004636:Emergency Service, Hospital; D005260:Female; D006801:Humans; D007121:Immunocompetence; D008297:Male; D010146:Pain; D012422:Rupture, Spontaneous / Q000150:complications / Q000382:microbiology / Q000628:therapy; D013275:Stomach Rupture / Q000150:complications* / Q000382:microbiology / Q000628:therapy; D013276:Stomach Ulcer / Q000150:complications* / Q000382:microbiology / Q000628:therapy; D014839:Vomiting
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B