Periodontal health and HIV infection.
Despite a large amount of research of periodontal health seen in HIV infection, much remains to be learned. Very few large controlled studies of infected people at settings not self-selected for oral disease have been reported, and few have investigated the necrotising periodontal diseases described in HIV infection. In this paper we present a brief review of three approaches to identify periodontal changes associated with HIV infection and identify possible aetiological factors for them. First, we summarise the methods and findings of a controlled blinded study of the periodontal health of homosexual men attending a genito-urinary medicine clinic. Second, we precis a case-control study of gingival ulceration among patients at a dedicated dental clinic. Finally, we outline how the validity of diagnostic criteria for HIV-associated periodontal changes were tested against the data collected in the controlled study.
Robinson
P G
PG
Department of Epidemiology and Public Health, University College, London, UK.
Sheiham
A
A
Challacombe
S J
SJ
Zakrzewska
J M
JM
D017088:AIDS-Related Opportunistic Infections / Q000209:etiology / Q000517:prevention & control; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D018791:CD4 Lymphocyte Count; D002180:Candidiasis, Oral / Q000209:etiology; D016022:Case-Control Studies; D005882:Gingival Diseases / Q000175:diagnosis / Q000209:etiology; D005892:Gingivitis, Necrotizing Ulcerative / Q000175:diagnosis / Q000209:etiology; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D019226:Oral Ulcer / Q000209:etiology*; D010510:Periodontal Diseases / Q000175:diagnosis / Q000209:etiology*; D011379:Prognosis; D012107:Research Design; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination