Morphologic hysteroscopic criteria suggestive of endometrial hyperplasia.
OBJECTIVE
To evaluate the morphologic hysteroscopic criteria leading to a diagnosis of endometrial hyperplasia and compare their accuracy with that of histology.


METHODS
A total of 95 hysteroscopic examinations were evaluated. Of these, 37 had a histologic diagnosis of normal endometrium and the remaining 58 of simple or complex endometrial hyperplasia. We compared the morphologic hysteroscopic criteria for the two groups using Pearson's chi-squared and Fisher's exact test.


RESULTS
Only the presence of endometrial glands presenting a cystic pattern at hysteroscopy gave statistically significant results (P < 0.05), with low sensitivity (15.79%), high specificity (97.29%) and a relative risk of 6.75. With a prevalence of endometrial hyperplasia of 22.97% in a population of women with metrorrhagia, the positive predictive value was 63.53% and the negative predictive value was 79.40%.


CONCLUSIONS
Additional, prospective studies are needed to determine the real value of the diagnostic morphologic parameters under consideration.
Uno
L H
LH
Department of Gynecology and Obstetrics, Faculty of Medicine, University of São Paulo, Brazil.
Sugimoto
O
O
Carvalho
F M
FM
Bagnoli
V R
VR
Fonseca
A M
AM
Pinotti
J A
JA
D000328:Adult; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D004714:Endometrial Hyperplasia / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology*; D005260:Female; D006801:Humans; D015907:Hysteroscopy / Q000379:methods*; D008875:Middle Aged; D011237:Predictive Value of Tests; D015995:Prevalence; D011446:Prospective Studies; D012680:Sensitivity and Specificity