title: [Glutamate oxalacetate and glutamate pyruvate aminotransferase activity in Streptomyces hygroscopicus 155 producing antibiotic complex].
abstract: Antibiotic activity, aminotransferase activity and composition of intracellular amino acids in low and high potent variants of Streptomyces hygroscopicus 155 were studied. The data of the study are indicative of some general regularities characteristic of amino acid metabolism in actinomycetes: an increased pool of the main aminodonor amino acids (alanine, asparaginic and glutaminic acids) and an increased activity of aminotransferases in the cultures of both the variants when grown in media with readily assimilable nitrogen sources.
authors.affiliation: National Collection of Microorganisms and Cell Cultures, Sofia, Bulgaria.
authors.forename: V A
authors.initials: VA
authors.lastname: Chipeva
authors.forename: I V
authors.initials: IV
authors.lastname: Ivanova
authors.forename: B
authors.initials: B
authors.lastname: Gocheva
mesh_terms: D000409:Alanine / Q000378:metabolism; D000410:Alanine Transaminase / Q000378:metabolism*; D000596:Amino Acids / Q000378:metabolism; D000643:Ammonium Chloride / Q000737:chemistry; D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D001219:Aspartate Aminotransferases / Q000378:metabolism*; D001412:Bacillus subtilis / Q000187:drug effects; D003470:Culture Media; D005285:Fermentation; D005998:Glycine / Q000378:metabolism; D008826:Microbial Sensitivity Tests; D013302:Streptomyces / Q000737:chemistry / Q000201:enzymology*
chemical_list: D000596:Amino Acids; D000900:Anti-Bacterial Agents; D003470:Culture Media; D000643:Ammonium Chloride; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000409:Alanine; D005998:Glycine
vernacular_title: Gluatamat-oksaloatsetat i glytamat-piruvat aminotransferaznaia aktivnost' u Streptomyces hygroscopicus 155-produtsenta antibiotichnogo komplekca.