[Effect of ascorbic acid on uric acid formation in men and animals].
The effect of the level of ascorbic acid on the formation of uric acid in the animals and human organisms has been learned. Activation of the hydroxylation of adenyl purins and uric acid by ascorbic acid has been found. A hypothesis was made about the activation of formation of glucocorticoids by ascorbic acid. Glucocorticoids, perhaps, lower the level of uric acid. Hypothesis was confirmed by experiments.
Sumbaev
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Iasinskaia
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D000225:Adenine / Q000737:chemistry; D000328:Adult; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D001205:Ascorbic Acid / Q000494:pharmacology*; D005938:Glucocorticoids / Q000378:metabolism* / Q000652:urine; D006168:Guinea Pigs; D006801:Humans; D006854:Hydrocortisone / Q000494:pharmacology; D006900:Hydroxylation; D014527:Uric Acid / Q000378:metabolism* / Q000652:urine
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D014527:Uric Acid; D000225:Adenine; D001205:Ascorbic Acid; D006854:Hydrocortisone
Vliianie ascorbinovoł kisloty na okiclenie adenina i obrazovanie mochevoł kisloty v organizme zhivotnykh i cheloveka