title: [Hepatocyte cytolysis enzymes as the markers of operative trauma in open cholecystectomy].
abstract: Surgical and narcotic aggression lead to certain injuries of hepatocytes. The authors followed up the time course of liver injury marker enzymes in two groups of patients subjected to open cholecystectomy (n = 62): succinate dehydrogenase (SDH), glutamate dehydrogenase (GIDH), SGPT, and SGOT. In group 1 the operative trauma was minimal, in group 2 traumatism was higher because of technological difficulties. A high diagnostic significance of SDH and GIDH is worthy of note: their activities increase in proportion with the severity of surgical trauma. Comparison of laboratory data helps objectively assess the severity of operative injury in open cholecystectomy.
authors.forename: M L
authors.initials: ML
authors.lastname: Zolotavina
authors.forename: S E
authors.initials: SE
authors.lastname: Gumeniuk
authors.forename: S N
authors.initials: SN
authors.lastname: Potemin
authors.forename: I V
authors.initials: IV
authors.lastname: Aksenov
authors.forename: M T
authors.initials: MT
authors.lastname: Proskuriakov
mesh_terms: D015415:Biomarkers; D002763:Cholecystectomy; D005969:Glutamate Dehydrogenase / Q000032:analysis*; D006801:Humans; D007431:Intraoperative Complications; D007064:L-Iditol 2-Dehydrogenase / Q000032:analysis*; D008099:Liver / Q000201:enzymology* / Q000293:injuries
chemical_list: D015415:Biomarkers; D007064:L-Iditol 2-Dehydrogenase; D005969:Glutamate Dehydrogenase; C061421:glutamate dehydrogenase (NAD(P)+)
vernacular_title: Fermenty tsitoliza gepatotsitov v otsenke operatsionnoĭ travmy pri otkrytoĭ kholetsistĕktomii.