[The characteristics of the immune disorders in primary and repeated craniocerebral trauma].
The immune shifts induced by initial and recurrent craniocerebral injuries were studied experimentally on white rats. It was found that in an initial injury the inhibition of cellular and humoral immunity occurred on the 1st posttraumatic day. In case of a recurrent injury taking place 30-40 days after an initial one, the alterations in cellular and humoral immunity were less pronounced. Autoimmune responses to the brain antigens were more intensive in a recurrent injury and could be revealed as soon as on the 1st posttraumatic day. It follows therefore that the results of this study evidence for the immune difference between initial and recurrent injuries.
Lisianyĭ
M I
MI
Rudenko
V A
VA
Hniedkova
I O
IO
Lisianyĭ
O M
OM
Horobets'
O V
OV
D000818:Animals; D000917:Antibody Formation; D015551:Autoimmunity; D001835:Body Weight; D001930:Brain Injuries / Q000276:immunology* / Q000473:pathology; D007111:Immunity, Cellular; D009929:Organ Size; D051381:Rats; D012008:Recurrence; D013601:T-Lymphocytes / Q000276:immunology; D013950:Thymus Gland / Q000473:pathology; D013997:Time Factors
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