title: Anticardiolipin antibodies in pre-eclampsia and intrauterine growth retardation.
abstract: OBJECTIVE
  To establish an association of anticardiolipin antibody (ACA) levels and pre-eclampsia or intrauterine growth retardation (IUGR).
  
  
  METHODS
  Twenty-eight patients with pre-eclampsia, 28 with IUGR and 28 normotensive control group were matched for maternal age, race, weight, cigarette smoking, and parity. All had plasma anticardiolipin antibodies (GPL and MPL) detected by the modified enzyme-linked immuno-absorbent assay (ELISA) technique.
  
  
  RESULTS
  No statistical significant difference in ACA values, both GPL and MPL, was found among the three groups studied Furthermore, none reached a value of ACA that could be considered clinically relevant (> 15).
  
  
  CONCLUSIONS
  No association was found in anticardiolipin antibody levels between pre-eclamptic and IUGR versus the control group.
authors.affiliation: Institute of Gynecology, University of Messina, Italy.
authors.forename: R
authors.initials: R
authors.lastname: D'Anna
authors.forename: A
authors.initials: A
authors.lastname: Scilipoti
authors.forename: J
authors.initials: J
authors.lastname: Leonardi
authors.forename: M
authors.initials: M
authors.lastname: Scuderi
authors.forename: V M
authors.initials: VM
authors.lastname: Jasonni
authors.forename: R
authors.initials: R
authors.lastname: Leonardi
mesh_terms: D000328:Adult; D017153:Antibodies, Anticardiolipin / Q000097:blood* / Q000276:immunology; D015331:Cohort Studies; D005260:Female; D005317:Fetal Growth Retardation / Q000097:blood / Q000276:immunology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood / Q000276:immunology; D007075:Immunoglobulin M / Q000097:blood / Q000276:immunology; D011225:Pre-Eclampsia / Q000097:blood / Q000276:immunology*; D011247:Pregnancy / Q000097:blood / Q000276:immunology*; D011446:Prospective Studies; D012016:Reference Values
chemical_list: D017153:Antibodies, Anticardiolipin; D007074:Immunoglobulin G; D007075:Immunoglobulin M