title: Nephron sparing surgery for de novo renal cell carcinoma in an allograft kidney: a case report.
abstract: De novo renal cell carcinoma in a renal allograft is rare and has special implications in renal transplant recipients. We describe a patient with a renal allograft who developed a de novo renal cell carcinoma in the functioning renal allograft 258 months after transplantation. The patient underwent enucleation of the tumor because preoperative MRI showed it was well-encapsulated. A DNA banding study showed that the tumor originated from the donor. Indications for conservative renal surgery in renal cell carcinoma have been increasing. Accordingly, 1 option in the treatment of de novo renal cell carcinoma in a functioning renal allograft is enucleation as a method of nephron sparing surgery.
authors.affiliation: Department of Urology, Shiga University of Medical Science, Otsu, Japan.
authors.forename: K I
authors.initials: KI
authors.lastname: Park
authors.forename: H
authors.initials: H
authors.lastname: Inoue
authors.forename: C J
authors.initials: CJ
authors.lastname: Kim
authors.forename: T
authors.initials: T
authors.lastname: Tomoyoshi
mesh_terms: D001345:Autoradiography; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D015342:DNA Probes / Q000737:chemistry; D004273:DNA, Neoplasm / Q000032:analysis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D016030:Kidney Transplantation / Q000009:adverse effects; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009399:Nephrons / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D011183:Postoperative Complications; D012086:Reoperation; D014057:Tomography, X-Ray Computed; D014184:Transplantation, Homologous
chemical_list: D015342:DNA Probes; D004273:DNA, Neoplasm