title: Trends in antimicrobial drug use in the community--France, 1981-1992.
abstract: Trends in the use of antimicrobials in France between 1980-1981 and 1991-1992 were analyzed. Data were obtained from surveys of health and ambulatory care, which were based on national probability samples. In a 3-month period in 1980, 17% of the population of France was treated with an antibiotic, compared with 25% in 1991 (P < .001). The frequency of respiratory tract infections with a presumed viral etiology that were diagnosed and treated with antibiotics increased by 86% for adults and 115% for children in the 11-year period. The proper use of cephalosporins must be encouraged, and vigilance is required in view of the increased improper use of fluoroquinolones, mainly for respiratory tract infections with a presumed viral etiology.
authors.affiliation: Institut National de la Santé et de la Recherche Médicale, Unité 21, Faculté de Medecine PARIS SUD, Villejuif, France. guillemot@vjf.inserm.fr
authors.forename: D
authors.initials: D
authors.lastname: Guillemot
authors.forename: P
authors.initials: P
authors.lastname: Maison
authors.forename: C
authors.initials: C
authors.lastname: Carbon
authors.forename: B
authors.initials: B
authors.lastname: Balkau
authors.forename: F
authors.initials: F
authors.lastname: Vauzelle-Kervroëdan
authors.forename: C
authors.initials: C
authors.lastname: Sermet
authors.forename: G
authors.initials: G
authors.lastname: Bouvenot
authors.forename: E
authors.initials: E
authors.lastname: Eschwège
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000890:Anti-Infective Agents / Q000627:therapeutic use; D002511:Cephalosporins / Q000627:therapeutic use; D002648:Child; D003625:Data Collection; D004363:Drug Utilization / Q000639:trends*; D024841:Fluoroquinolones; D005602:France; D006801:Humans; D007239:Infections / Q000188:drug therapy*; D012141:Respiratory Tract Infections / Q000188:drug therapy / Q000821:virology; D014777:Virus Diseases / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D002511:Cephalosporins; D024841:Fluoroquinolones