Assignment of the human fast skeletal muscle troponin C gene (TNNC2) between D20S721 and GCT10F11 on chromosome 20 by somatic cell hybrid analysis.
The chromosomal location of the human fast skeletal muscle troponin C (TNNC2) gene was determined using somatic cell hybrids. PCR-based analysis of a 'monochromosomal' hybrid panel identified the presence of the TNNC2 gene on human chromosome 20 and subsequent analysis of the Genebridge4 radiation hybrid panel located the gene between D20S721 and GCT10F11 with a lod score of > 3.
Townsend
P J
PJ
Imperial College School of Medicine, National Heart and Lung Institute, London.
Yacoub
M H
MH
Barton
P J
PJ
D002874:Chromosome Mapping; D002890:Chromosomes, Human, Pair 20 / Q000235:genetics*; D004247:DNA / Q000032:analysis; D005819:Genetic Markers; D006801:Humans; D006822:Hybrid Cells / Q000737:chemistry*; D018656:Muscle Fibers, Fast-Twitch / Q000737:chemistry*; D016133:Polymerase Chain Reaction; D019209:Troponin C / Q000235:genetics*
D005819:Genetic Markers; D019209:Troponin C; D004247:DNA