title: Overview: hyperacute rt-PA stroke treatment. The NINDS rt-PA Stroke Study Group.
abstract: Ischemic stroke remains a significant problem in the United States. Complex intracellular metabolic events occur leading to cell death. A search for treatments to prevent this ischemic process continues. Thrombolytic agents, recently developed and tested, may lessen the disabling effects of stroke.
authors.affiliation: Long Island Jewish Medical Center, Department of Neurology, New York, New York 11040, USA.
authors.forename: R
authors.initials: R
authors.lastname: Donnarumma
authors.forename: G
authors.initials: G
authors.lastname: Kongable
authors.forename: C
authors.initials: C
authors.lastname: Barch
authors.forename: J
authors.initials: J
authors.lastname: Braimah
authors.forename: P
authors.initials: P
authors.lastname: Bratina
authors.forename: S
authors.initials: S
authors.lastname: Daley
authors.forename: K
authors.initials: K
authors.lastname: Rapp
authors.forename: S
authors.initials: S
authors.lastname: Sailor
authors.forename: J
authors.initials: J
authors.lastname: Spilker
mesh_terms: D002545:Brain Ischemia / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D002561:Cerebrovascular Disorders / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D006233:Persons with Disabilities; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D010960:Plasminogen Activators / Q000494:pharmacology / Q000627:therapeutic use*; D011994:Recombinant Proteins / Q000494:pharmacology / Q000627:therapeutic use*; D010959:Tissue Plasminogen Activator / Q000494:pharmacology / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents; D011994:Recombinant Proteins; D010960:Plasminogen Activators; D010959:Tissue Plasminogen Activator