[Effect of Scutellaria baicalensis extract on the immunologic status of patients with lung cancer receiving antineoplastic chemotherapy].
Cytostatic therapy of patients with lung cancer is attended with decrease in the relative number of T-lymphocytes and their theophylline-resistant population. Patients who were given SB showed a tendency towards increase of these parameters during antitumor chemotherapy. The immunoregulation index (IRI) in this case was approximately twice the background values during the whole period of investigation. The inclusion of SB in the therapeutic complex promotes increase in the number of immunoglobulins A at a stable level of immunoglobulins G.
Smol'ianinov
E S
ES
Institute of Pharmacology Tomsk Research Center, Russian Academy of Medical Sciences, Russia.
Gol'dberg
V E
VE
Matiash
M G
MG
Ryzhakov
V M
VM
Boldyshev
D A
DA
Litvinenko
V I
VI
Dygaĭ
A M
AM
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D001402:B-Lymphocytes / Q000187:drug effects / Q000276:immunology; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000009:adverse effects; D004317:Doxorubicin / Q000008:administration & dosage / Q000009:adverse effects; D004731:Endotoxins; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood; D007074:Immunoglobulin G / Q000097:blood; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects; D008875:Middle Aged; D009367:Neoplasm Staging; D010946:Plants, Medicinal; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology
D000276:Adjuvants, Immunologic; D004731:Endotoxins; D007070:Immunoglobulin A; D007074:Immunoglobulin G; D004317:Doxorubicin; D003520:Cyclophosphamide; D008727:Methotrexate
Vliianie ékstracta shlemnika baĭkal'skogo na immunologicheskiĭ status bol'nykh rakom legkogo v usloviiakh protivoopukholevoĭ khimioterapii.