[Effect of triton x-100 and glutaraldehyde on Ca2+- and Mg2+-ATPase activity of erythrocytes during irradiation].
The effect of triton X-100 and glutaraldehyde on the changes in Ca(2+)- and Mg(2+)-ATPase activity of erythrocyte plasma membrane under irradiation of rat erythrocytes has been studied. It was found that irradiation of erythrocyte ghosts in a dose of 1000 Gy leads to the inhibition of the both enzymes. Triton X-100 enhanced the radiation effect, while glutaraldehyde decreased Ca(2+)-ATPase sensitivity to the action of radiation. The mechanisms of the effects observed are discussed.
Finashin
A V
AV
Krupin
V D
VD
Tovstiak
V V
VV
D000818:Animals; D017301:Ca(2+) Mg(2+)-ATPase / Q000097:blood / Q000187:drug effects*; D000252:Calcium-Transporting ATPases / Q000097:blood / Q000187:drug effects*; D003902:Detergents; D004910:Erythrocyte Membrane / Q000187:drug effects* / Q000201:enzymology / Q000528:radiation effects / Q000648:ultrastructure; D005976:Glutaral / Q000494:pharmacology*; D017830:Octoxynol / Q000494:pharmacology*; D051381:Rats
D003902:Detergents; D017830:Octoxynol; D017301:Ca(2+) Mg(2+)-ATPase; D000252:Calcium-Transporting ATPases; D005976:Glutaral
Vliianie tritona X-100 i glutarovogo al'degida na aktivnost' Ca2+- i Mg2+-ATP-az éritrotsitov pri obluchenii.