title: Discordant splenic uptake of Tc-99m colloid and Tc-99m denatured RBC in candidiasis-endocrinopathy syndrome.
abstract: We report discordant splenic uptake of Tc-99m colloid and Tc-99m heat-denatured red blood cells (RBC) which occurred in a 21-year-old female with candidiasis-endocrinopathy syndrome. Tc-99m colloid liver-spleen imaging showed no splenic uptake, suggesting the presence of functional asplenia. A subsequent Tc-99m heat-denatured RBC study clearly revealed a small spleen with preserved sequestrating function. These results may demonstrate that the qualitative dissociation of splenic functions in processing colloid and denatured RBC in functional asplenia: the sequestration function remains while the reticuloendothelial system is impaired.
authors.affiliation: Department of Radiology, Asahikawa Medical College Hospital, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Aburano
authors.forename: R
authors.initials: R
authors.lastname: Katada
authors.forename: N
authors.initials: N
authors.lastname: Shuke
authors.forename: W
authors.initials: W
authors.lastname: Yamamoto
authors.forename: T
authors.initials: T
authors.lastname: Kawakami
authors.forename: I
authors.initials: I
authors.lastname: Makino
authors.forename: J
authors.initials: J
authors.lastname: Sato
authors.forename: Y
authors.initials: Y
authors.lastname: Ishikawa
mesh_terms: D000328:Adult; D002179:Candidiasis, Cutaneous / Q000000981:diagnostic imaging*; D004912:Erythrocytes; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging; D016884:Polyendocrinopathies, Autoimmune / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D013154:Spleen / Q000000981:diagnostic imaging*; D013577:Syndrome; D013667:Technetium / Q000493:pharmacokinetics; D014018:Tissue Distribution; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D013667:Technetium