Bringing genetic tests into the clinic.
The tests tend to become possible soon after the discovery of a disease-related gene. Hence, they often become available before any interventions are known to be effective. They may also arrive before extensive knowledge regarding their clinical validity. To ensure their safe and effective use, physicians must face several issues--in which the crucial point may be not so much that a test is genetic as that it is used predictively.
Holtzman
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Johns Hopkins University School of Medicine, Baltimore, USA.
D001291:Attitude of Health Personnel; D005260:Female; D030342:Genetic Diseases, Inborn / Q000175:diagnosis* / Q000523:psychology; D005820:Genetic Testing / Q000379:methods*; D006801:Humans; D008297:Male; D008967:Molecular Biology; D010375:Pedigree; D011237:Predictive Value of Tests