[Marker proteins in cerebrospinal fluid of patients with grave craniocerebral injury].
The permeability of the blood-brain barrier for the cerebrospinal fluid marker proteins has been assessed in patients with grave craniocerebral injuries. The content of albumin and alpha 2-macroglobulin in the survivors decreased with time and by day 7 after the injury was virtually normal. In patients who died the content of these proteins was reliably increased starting from day 1. By day 7 the content of albumin in the cerebrospinal fluid approached the norm in this group, whereas the content of alpha 2-macroglobulin remained increased. The level of IgG surpassed the normal value on day 1 only in the patients who died, and later it did not differ from the norm in both groups.
Kuksinskiĭ
V A
VA
Churliaev
Iu A
IuA
Nikiforova
N V
NV
Lutsik
A A
AA
Lykova
O F
OF
D000418:Albumins / Q000134:cerebrospinal fluid*; D015415:Biomarkers; D001930:Brain Injuries / Q000134:cerebrospinal fluid* / Q000503:physiopathology; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid*; D000511:alpha-Macroglobulins / Q000134:cerebrospinal fluid*
D000418:Albumins; D015415:Biomarkers; D007074:Immunoglobulin G; D000511:alpha-Macroglobulins
Soderzhanie belkov-markerov v spinnomozgovoĭ zhidkosti pri tiazheloĭ cherepno-mozgovoĭ travme.