title: [Resistance to organophosphate insecticides in Culex pipiens L. (Diptera: Culicidae) and first signal of the presence of A5-B5 esterase in Italy].
abstract: After a short review on insecticide resistance in mosquitoes, the results of a study on organophosphate (OP) resistance, carried out on 2 Culex pipiens L. field populations from North-eastern Italy, are reported. The A1 an A4-B4 or A5-B5 esterases were detected in our sample by starch gel electrophoresis. In order to differentiate between A4-B4 and A5-B5 esterases, restriction fragment length polymorphism (RFLP) analysis at the esterases B locus was performed: both A4-B4 and A5-B5 aplotipes were found in one of the studied populations. This is the first record of A5-B5 esterases in continental Europe.
authors.affiliation: Laboratorio di Parassitologia, Istituto Superiore di Sanità, Roma.
authors.forename: C
authors.initials: C
authors.lastname: Severini
authors.forename: R
authors.initials: R
authors.lastname: Romi
authors.forename: R
authors.initials: R
authors.lastname: Zamburlini
authors.forename: V
authors.initials: V
authors.lastname: Di Pardo
authors.forename: M
authors.initials: M
authors.lastname: Marinucci
authors.forename: G
authors.initials: G
authors.lastname: Pierdominici
mesh_terms: D000818:Animals; D003465:Culex / Q000187:drug effects / Q000201:enzymology*; D007305:Insecticide Resistance; D007306:Insecticides / Q000494:pharmacology*; D007558:Italy; D009943:Organophosphorus Compounds; D012697:Serine Endopeptidases / Q000032:analysis*
chemical_list: D007306:Insecticides; D009943:Organophosphorus Compounds; D012697:Serine Endopeptidases; C049262:esterase B
vernacular_title: La resistenza agli insetticidi fosforganici in Culex pipiens L. (Diptera: Culicidae) e prima segnalazione della presenza delle esterasi A5-B5 in Italia.