[Improvement of storage capability of blood by the use of biocompatible absorbents].
A new filtration method for leucocyte and chloride ion depletion of erythrocyte concentrates in one step by DEAE cellulose was developed. After passage of the packed red cells through this filter material a chloride depletion of 70-80% and a leucocyte depletion of 90% could be reached. The 25 degrees C storage of this in-line-filtered red cells characterized by metabolic parameters (ATP, 2,3-DPG) suggests the possibility of a long-term red blood cell storage.
Mavrina
L
L
Institut für Transfusionsmedizin, Universitätsklinikum Charité, Humboldt-Universität zu Berlin, Berlin.
Matthes
G
G
Frank
S
S
Loth
F
F
Melnikowa
V
V
D000042:Absorption; D001672:Biocompatible Materials; D001793:Blood Preservation / Q000295:instrumentation / Q000379:methods*; D002469:Cell Separation / Q000379:methods; D003636:DEAE-Cellulose; D004912:Erythrocytes; D005374:Filtration / Q000379:methods; D006801:Humans; D007962:Leukocytes / Q000166:cytology; D013997:Time Factors
D001672:Biocompatible Materials; D003636:DEAE-Cellulose
Untersuchungen zur Verbesserung der Lagerfähigkeit von Blutkonserven durch Einsatz von biokompatiblen Adsorbenzien.