title: Repetition priming with nonverbal stimuli in patients with dementia of the Alzheimer type.
abstract: Perceptual repetition priming was examined in patients with dementia of the Alzheimer type (DAT) and normal control (NC) participants using a task involving the discrimination of geometric designs that had either a continuous ("closed") or discontinuous ("open") perimeter. With the open stimuli, the groups displayed significant and equivalent levels of priming after immediate repetition of the stimuli, whereas only the NC group primed significantly over a delay of three intervening items. Neither group demonstrated significant priming with the closed stimuli. Results indicate that under some conditions DAT patients can exhibit normal repetition priming with stimuli that do not have preexisting representations but that (due possibly to a deficiency in the level of steady-state cortical activation) this priming dissipates more rapidly in DAT patients than in NC participants.
authors.affiliation: Department of Psychology, Brown University, Providence, Rhode Island 02912, USA. wheindel@brownvm.brown.edu
authors.forename: W C
authors.initials: WC
authors.lastname: Heindel
authors.forename: D P
authors.initials: DP
authors.lastname: Salmon
authors.forename: C
authors.initials: C
authors.lastname: Fennema-Notestine
authors.forename: A S
authors.initials: AS
authors.lastname: Chan
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000523:psychology*; D003071:Cognition / Q000502:physiology*; D003463:Cues; D004192:Discrimination, Psychological / Q000502:physiology; D005260:Female; D005556:Form Perception / Q000502:physiology; D006801:Humans; D008297:Male; D011597:Psychomotor Performance; D011930:Reaction Time / Q000502:physiology