title: Parry-Romberg syndrome: follow-up imaging during suppressive therapy.
abstract: Parry-Romberg syndrome is a poorly--understood disorder characterized by progressive hemifacial atrophy involving the skin, soft tissue, and bone. Involvement of the central nervous system with impairment in neurologic function occurs infrequently. We describe a child with this syndrome in whom central nervous system involvement, documented on serial MRI, played a prominent role. We have attempted to correlate the clinical course with the radiologic findings, and to determine the impact of prednisone and methotrexate on the intracranial lesions.
authors.affiliation: Department of Neurology, Children's Hospital Medical Center, Cincinnati 45229-3039, USA.
authors.forename: H
authors.initials: H
authors.lastname: Goldberg-Stern
authors.forename: T
authors.initials: T
authors.lastname: deGrauw
authors.forename: M
authors.initials: M
authors.lastname: Passo
authors.forename: W S
authors.initials: WS
authors.lastname: Ball
mesh_terms: D001921:Brain / Q000473:pathology*; D002648:Child; D005150:Facial Hemiatrophy / Q000188:drug therapy* / Q000473:pathology*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008279:Magnetic Resonance Imaging; D008727:Methotrexate / Q000627:therapeutic use*; D011241:Prednisone / Q000627:therapeutic use*
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D011241:Prednisone; D008727:Methotrexate