title: Possible therapeutic effects of growth hormone on wound healing in the diabetic patient.
abstract: Growth factors are increasingly investigated for their role in wound healing. The authors present evidence from human and animal studies suggesting that growth hormone induces a positive nitrogen balance, enhances connective-tissue synthesis, and increases lean body mass. The physiology of diabetes and wound healing is reviewed in the context of how growth hormone therapy could benefit this patient population.
authors.affiliation: Pennsylvania College of Podiatric Medicine, Philadelphia 19107, USA.
authors.forename: K A
authors.initials: KA
authors.lastname: Massey
authors.forename: C
authors.initials: C
authors.lastname: Blakeslee
authors.forename: H S
authors.initials: HS
authors.lastname: Pitkow
mesh_terms: D000818:Animals; D003920:Diabetes Mellitus / Q000378:metabolism* / Q000503:physiopathology; D004359:Drug Therapy, Combination; D019382:Human Growth Hormone / Q000378:metabolism / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D007328:Insulin / Q000378:metabolism; D007334:Insulin-Like Growth Factor I / Q000008:administration & dosage; D051381:Rats; D013514:Surgical Procedures, Operative; D014945:Wound Healing / Q000187:drug effects* / Q000502:physiology
chemical_list: D007328:Insulin; D019382:Human Growth Hormone; D007334:Insulin-Like Growth Factor I