[A study of erythrocyte oxidative enzyme activity in patients with laryngeal cancer before and after treatment with a selenium preparation CEROSEL].
The preliminary results of activity changes of antioxidant enzymes (glutathione peroxidase, catalase and superoxide dismutase) in erythrocyte in 19 patients with laryngeal cancer were presented. Enzymes activity in patients was signified three times: before surgery, before and after radiotherapy. During Co-60-therapy patients received leaven preparation of selenium CE-ROSEL in dose 100 micrograms Se/day. Obtained results showed increase of enzymes activity after CE-ROSEL supplementation. This changes are probably the result of selenium influence on protected mechanism before the free radicals.
Namysłowski
G
G
II Katedry i Kliniki Laryngologii Slaskiej AM, Zabrzu.
Nowińska
E
E
Danch
A
A
Drózdz
M
M
Wójcik
A
A
Posielezna
B
B
Czecior
E
E
Anczykowska
M
M
D002374:Catalase / Q000187:drug effects / Q000378:metabolism; D003037:Cobalt Radioisotopes / Q000627:therapeutic use*; D004912:Erythrocytes / Q000187:drug effects / Q000201:enzymology*; D005260:Female; D005979:Glutathione Peroxidase / Q000187:drug effects / Q000378:metabolism; D006801:Humans; D007822:Laryngeal Neoplasms / Q000201:enzymology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010088:Oxidoreductases / Q000187:drug effects*; D011300:Preoperative Care; D018714:Radiotherapy, Adjuvant; D012643:Selenium / Q000008:administration & dosage*; D013482:Superoxide Dismutase / Q000187:drug effects / Q000378:metabolism
D003037:Cobalt Radioisotopes; D010088:Oxidoreductases; D002374:Catalase; D005979:Glutathione Peroxidase; D013482:Superoxide Dismutase; D012643:Selenium
Badania zmian aktywności enzymów antyoksydacyjnych w krwinkach pacjentów z rakiem krtani przed i po podaniu preparatu selenowego CEROSEL.