Effects on left ventricular mass and function of low doses of enalapril for systemic hypertension.
After 7 years of treatment with 20 mg of enalapril twice daily, regression of the initial left ventricular hypertrophy in a group of 24 patients with essential arterial hypertension was achieved: gradual reduction in the dosage to 10 or 5 mg twice daily caused no worsening of either blood pressure or ventricular structure or function.
González-Juanatey
J R
JR
Cardiology Department and Hypertension Unit, Complexo Hospitalario Universitario de Santiago de Compostela, Spain.
Reino
A P
AP
García-Acuña
J M
JM
Varela Román
A
A
Calvo Gómez
C
C
Cabezas-Cerrato
J
J
D000328:Adult; D000368:Aged; D000959:Antihypertensive Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001794:Blood Pressure; D018619:Echocardiography, Doppler, Pulsed; D004656:Enalapril / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy*; D017379:Hypertrophy, Left Ventricular / Q000000981:diagnostic imaging / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D016277:Ventricular Function, Left / Q000187:drug effects
D000959:Antihypertensive Agents; D004656:Enalapril