title: [Experimental data on pharmacological effects of new phenothiazine derivatives].
abstract: A variety of triazoles and thiadiazoles linked to the N-atom of the phenothiazine through a two carbon atoms chain have been submitted to preliminary toxicological screening (DL50 and DMT). Two derivatives have been selected for the specific pharmacological evaluation. It has been noted a diminution of the exploratory capacity without the muscle tonus, the balance and the capacity of becoming normal again of the tested animals (mice and rats) being affected.
authors.affiliation: Faculté de Chimie, Université AI. I. Cuza Iasi, România.
authors.forename: E
authors.initials: E
authors.lastname: Bâcu
authors.forename: M
authors.initials: M
authors.lastname: Petrovanu
authors.forename: C
authors.initials: C
authors.lastname: Antohie
authors.forename: I
authors.initials: I
authors.lastname: Ciocoiu
authors.forename: O C
authors.initials: OC
authors.lastname: Mungiu
mesh_terms: D000818:Animals; D014150:Antipsychotic Agents / Q000494:pharmacology*; D001522:Behavior, Animal / Q000187:drug effects; D007928:Lethal Dose 50; D010640:Phenothiazines / Q000494:pharmacology*
chemical_list: D014150:Antipsychotic Agents; D010640:Phenothiazines
vernacular_title: Données expérimentales concernant les effets pharmacologiques de quelques nouveaux dérivés phénothiaziniques.