title: Assessment of genome damage in occupational exposure to ionising radiation and ultrasound.
abstract: The mutagenic effects of low doses of radiation on occupationally exposed subjects were studied on lymphocyte culture using two methods: analysis of structural chromosome aberrations and micronucleus assay. The results obtained in subjects exposed to ionising radiation alone were compared to those exposed to both ionising radiation and ultrasound. A correlation between the total number of chromosome aberrations and distribution of micronuclei in the genome of somatic cells show higher deviation in the group exposed to X-ray and ultrasound than in the group exposed to X-rays alone. The degree of genome damage in occupational exposure to X-rays and ultrasound were discussed.
authors.affiliation: Institute for Medical Research and Occupational Health, Ksaverska, Zagreb, Croatia.
authors.forename: G V
authors.initials: GV
authors.lastname: Vera
authors.forename: F
authors.initials: F
authors.lastname: Aleksandra
authors.forename: K
authors.initials: K
authors.lastname: Dragan
authors.forename: H
authors.initials: H
authors.lastname: Andrija
mesh_terms: D000328:Adult; D002869:Chromosome Aberrations; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects; D008297:Male; D015162:Micronucleus Tests; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D014463:Ultrasonography / Q000009:adverse effects*; D014965:X-Rays / Q000009:adverse effects*