Subcutaneous T-cell lymphoma in a patient with rheumatoid arthritis not treated with cytotoxic agents.
This case report describes an 81-year-old patient with prolonged rheumatoid arthritis (RA), which was complicated by the occurrence of a subcutaneous T-cell lymphoma. During the course of his illness the patient had not been treated with disease-modifying agents (i.e. cytotoxic agents), but only symptomatically with anti-inflammatory drugs. This finding demonstrates a previously undescribed association between RA and a rare from of subcutaneous T-cell lymphoma, which may add more information to the controversial issue of emergence of malignancy in RA.
Levy
Y
Y
The Department of Medicine B, Sheba Medical Center and Sackler Faculty of Medicine, Tel-Hashomer, Israel.
George
J
J
Abraham
A
A
Afek
A
A
Livneh
A
A
Shoenfeld
Y
Y
D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy; D001706:Biopsy; D017809:Fatal Outcome; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000150:complications* / Q000473:pathology; D008297:Male
D000894:Anti-Inflammatory Agents, Non-Steroidal