title: Mandibular distraction osteogenesis in the treatment of upper airway obstruction in children with craniofacial deformities.
abstract: Over the past 3 years, 16 patients (12 males, 4 females) have undergone mandibular distraction osteogenesis in conjunction with soft-tissue procedures to treat medically refractory obstructive sleep apnea. Thirty distraction devices were placed for bilateral distraction in 14 children and unilateral distraction in 2. The mean age of treatment was 4 years and 8 months (range 14 weeks to 12 years and 8 months). Eight of the patients had failed conventional medical and surgical treatment of obstructive sleep apnea and were considered tracheostomy candidates, whereas the remaining eight had tracheostomies placed shortly after birth for upper airway obstruction. These eight children could not be decannulated by standard protocols. The average distraction distance was 25 mm (range 18 to 35 mm). To date, seven of the eight patients with tracheostomies have been decannulated, and one is still in progress. Clinical improvement in the signs and symptoms of sleep apnea and reduction or elimination of preoperative oxygen requirements occurred in seven of the eight children with medically refractory sleep apnea. Twelve-channel polysomnograms were obtained preoperatively and postoperatively in each of the eight patients without tracheostomies. Respiratory disturbance index decreased from a mean of 7.1 to 1.7 after surgery. Lowest oxygen saturation rose from a mean of 0.70 to 0.89 after surgery. Application of mandibular distraction osteogenesis is an important component in the treatment of obstructive sleep apnea and permits mandibular advancement in the younger child. As more experience is gained with distraction osteogenesis in the treatment of children with obstructive sleep apnea, the role of distraction will become better defined.
authors.affiliation: Center for Craniofacial Disorders, Scottish Rite Children's Medical Center, Atlanta, Georgia 30342, USA.
authors.forename: S R
authors.initials: SR
authors.lastname: Cohen
authors.forename: C
authors.initials: C
authors.lastname: Simms
authors.forename: F D
authors.initials: FD
authors.lastname: Burstein
mesh_terms: D000402:Airway Obstruction / Q000209:etiology / Q000601:surgery*; D002648:Child; D002675:Child, Preschool; D019465:Craniofacial Abnormalities / Q000150:complications*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008334:Mandible / Q000601:surgery*; D019857:Osteogenesis, Distraction / Q000379:methods*; D012891:Sleep Apnea Syndromes / Q000209:etiology / Q000601:surgery*; D014139:Tracheostomy