title: Comparative study of the toxic actions of 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane and 2,2-bis(p-chlorophenyl)-1,1-dichloroethylene on the growth and respiratory activity of a microorganism used as a model.
abstract: A strain of Bacillus stearothermophilus was used as a model for a comparative study of the toxic effect of 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane and 2,2-bis(p-chlorophenyl)-1,1-dichloroethylene. Bacterial growth, the O2 consumption rate, and respiration-related enzymatic activities provided quantitative data in agreement with results reported for other systems. The use of this bacterium for screening for chemical toxicity is discussed.
authors.affiliation: Centro de Neurociências, Universidade de Coimbra, Portugal.
authors.forename: M M
authors.initials: MM
authors.lastname: Donato
authors.forename: A S
authors.initials: AS
authors.lastname: Jurado
authors.forename: M C
authors.initials: MC
authors.lastname: Antunes-Madeira
authors.forename: V M
authors.initials: VM
authors.lastname: Madeira
mesh_terms: D002455:Cell Division / Q000187:drug effects; D003634:DDT / Q000633:toxicity*; D003633:Dichlorodiphenyl Dichloroethylene / Q000633:toxicity*; D004352:Drug Resistance, Microbial; D001411:Geobacillus stearothermophilus / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D007306:Insecticides / Q000633:toxicity*; D008954:Models, Biological; D010084:Oxidation-Reduction; D010101:Oxygen Consumption / Q000187:drug effects
chemical_list: D007306:Insecticides; D003633:Dichlorodiphenyl Dichloroethylene; D003634:DDT