Pancytopaenia from a disseminated anaplastic oligodendroglioma.
The rarity of extraneural metastases from a central nervous system (CNS) tumour may mean that the manifestations of a metastatic lesion are confused with a second pathology. This report concerns a patient who developed a fatal and clinically unexplained, pancytopaenia 3 months after removal of an anaplastic oligodendroglioma. Postmortem revealed widespread bone marrow dissemination of the CNS primary and a solitary liver metastasis. A brief review of the literature and some possible reasons for the rarity of extracranial metastases are discussed.
Dawson
T P
TP
Department of Histopathology, University of Wales College of Medicine, Cardiff, UK.
D000328:Adult; D015415:Biomarkers / Q000032:analysis; D019046:Bone Marrow Neoplasms / Q000556:secondary; D017809:Fatal Outcome; D005904:Glial Fibrillary Acidic Protein / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009837:Oligodendroglioma / Q000737:chemistry / Q000473:pathology*; D010198:Pancytopenia / Q000150:complications*; D016708:Synaptophysin / Q000032:analysis
D015415:Biomarkers; D005904:Glial Fibrillary Acidic Protein; D016708:Synaptophysin