[Penetrating duodenal ulcer as a complication of a hepatic artery port catheter in hepatic metastasis of sigmoid carcinoma].
METHODS
We report a typical complication of hepatic artery infusion therapy (HAI) in a patient with colon cancer metastatic to the liver. One year after the last HAI-therapy the patient presented with upper gastrointestinal bleeding. Endoscopy showed a large duodenic ulcer penetrating into an adjacent hepatic colon cancer metastasis. The hepatic artery catheter was visible at the ground of the duodenic ulcer.


CONCLUSIONS
Thirty-five percent of patients under HAI-therapy develop gastric/duodenic ulcers. The severity of the HAI complication presented here, however, is quite uncommon.
Jäger
D
D
II. Medizinische Klinik, Krankenhaus Nordwest, Frankfurt.
Warzelhan
J
J
Jäger
E
E
Knuth
A
A
D000230:Adenocarcinoma / Q000188:drug therapy / Q000556:secondary*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects*; D002408:Catheters, Indwelling; D004381:Duodenal Ulcer / Q000139:chemically induced* / Q000473:pathology; D004386:Duodenum / Q000187:drug effects / Q000473:pathology; D016099:Endoscopy, Gastrointestinal; D005472:Fluorouracil / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000295:instrumentation*; D007413:Intestinal Mucosa / Q000187:drug effects / Q000473:pathology; D002955:Leucovorin / Q000008:administration & dosage / Q000009:adverse effects*; D008113:Liver Neoplasms / Q000188:drug therapy / Q000556:secondary*; D008297:Male; D010439:Peptic Ulcer Perforation / Q000139:chemically induced* / Q000473:pathology; D012811:Sigmoid Neoplasms / Q000188:drug therapy*
D002955:Leucovorin; D005472:Fluorouracil
Penetrierendes Ulcus duodeni als Komplikation eines Arteria-hepatica-Portkatheters bei hepatisch metastasiertem Sigmakarzinom.