title: [Frequency of sister chromatid exchanges (SCE)in peripheral blood lymphocytes from stainless steel welders].
abstract: In order to detect the genotoxic effects of nickel (Ni) and chromium (Cr) contained in welding fumes on humans, sister chromatid exchanges (SCEs) frequency in lymphocytes was determined in the blood samples derived from 39 stainless steel welders and compared with the data obtained from 22 sex and age matched unexposed controls. The frequency of SCEs was higher in the welders than in the controls. Smoking proved to be a significant, positive predictor for SCE frequency in the controls but not in the welders. Significant correlation between SCE and chromium concentrations in urine of smoking welders was found. A possible synergism between chromium exposure and smoking is discussed. Neither age and urine nickel concentrations nor duration of exposure was a significant predictor for SCE frequency.
authors.affiliation: Oddziału Klinicznego Chorób Zawodowych, Pomorskiej Akademii Medycznej w Szczecinie.
authors.forename: M
authors.initials: M
authors.lastname: Myślak
authors.forename: K
authors.initials: K
authors.lastname: Kośmider
mesh_terms: D000328:Adult; D002857:Chromium / Q000009:adverse effects* / Q000652:urine; D004784:Environmental Monitoring; D006801:Humans; D008214:Lymphocytes / Q000166:cytology*; D008875:Middle Aged; D009532:Nickel / Q000009:adverse effects*; D016273:Occupational Exposure / Q000009:adverse effects*; D012854:Sister Chromatid Exchange; D012907:Smoking / Q000009:adverse effects; D013193:Stainless Steel; D014896:Welding
chemical_list: D002857:Chromium; D013193:Stainless Steel; D009532:Nickel
vernacular_title: Czestość wymian siostrzanych chromatyd (SCE) w limfocytach krwi obwodowej spawaczy stali nierdzewnych.