title: Continuous estimation of CO2 production during exercise.
abstract: A new method was developed for continuous isotopic estimation of human whole body CO2 rate of appearance (Ra) during non-steady state exercise. The technique consisted of a breath-by-breath measurement of 13CO2 enrichment (E) and a real-time fuzzy logic feedback system which controlled NaH13CO3 infusion rate to achieve an isotopic steady state. Ra was estimated from the isotope infusion rate and body 13CO2 enrichment which was equal to E at the isotopic steady state. During a non-steady state incremental cycle exercise (5 w/min or 10 w/min), NaH13CO3 infusion rate was successfully increased by the action of feedback controller so as to keep E constant.
authors.affiliation: Laboratory for Exercise Physiology and Biomechanics, Graduate School of Education, University of Tokyo, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Soma
authors.forename: Y
authors.initials: Y
authors.lastname: Yamamoto
mesh_terms: D000328:Adult; D001944:Breath Tests; D002245:Carbon Dioxide / Q000502:physiology*; D017143:Fuzzy Logic; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic; D005082:Physical Exertion; D011659:Pulmonary Gas Exchange; D012119:Respiration
chemical_list: D002245:Carbon Dioxide