title: Postmortem analysis of consecutively retrieved asymmetric porous-coated tibial components.
abstract: The objective of this investigation was to conduct a postmortem analysis of 8 porous-coated asymmetric tibial components to measure the extent of radiolucencies and bone ingrowth. With the use of radiographic, electron microscope, and histologic analysis techniques, a quantitative postmortem study of 8 consecutively retrieved porous-coated tibial components was conducted. Time in situ averaged 47+/-36 months. The components were secured with 4 pegs and 2 screws. Autograft bone chips were applied to the resected tibia during implantation. Contact radiographs of an average of 8 3-mm sections from each implant revealed that 73%+/-17% of the porous coating had no apparent radiolucencies present between the host bone and porous coating for the series. Backscattered electron imaging showed that the bone ingrowth averaged 6%+/-2%. Histologic analysis was unable to demonstrate any adverse cellular response. The analysis suggested that this asymmetric implant design is stable and biocompatible and has potential for long-term clinical durability.
authors.affiliation: Bone and Joint Research Laboratory, VA Medical Center, Salt Lake City, UT 84148, USA.
authors.forename: R D
authors.initials: RD
authors.lastname: Bloebaum
authors.forename: K N
authors.initials: KN
authors.lastname: Bachus
authors.forename: J W
authors.initials: JW
authors.lastname: Jensen
authors.forename: A A
authors.initials: AA
authors.lastname: Hofmann
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee; D001672:Biocompatible Materials; D001860:Bone Plates; D001863:Bone Screws; D016025:Bone Transplantation / Q000000981:diagnostic imaging / Q000473:pathology; D002102:Cadaver; D006801:Humans; D007720:Knee Prosthesis; D008297:Male; D008855:Microscopy, Electron, Scanning; D010784:Photomicrography; D011095:Polyethylenes; D016062:Porosity; D011859:Radiography; D013977:Tibia / Q000000981:diagnostic imaging / Q000601:surgery / Q000648:ultrastructure
chemical_list: D001672:Biocompatible Materials; D011095:Polyethylenes