title: Phenylethanolamine N-methyltransferase mRNA in rat hypothalamus and cerebellum.
abstract: Using the reverse transcription polymerase chain reaction, we detected a single form of phenylethanolamine N-methyltransferase (PNMT) mRNA in hypothalamus and medulla/pons and two forms in cerebellum. These findings indicate that the PNMT gene is expressed in these brain areas and suggest that tissue specific splicing of PNMT mRNA may occur.
authors.affiliation: Department of Biology, Virginia Commonwealth University, Richmond 23284-2012, USA.
authors.forename: J L
authors.initials: JL
authors.lastname: Andreassi
authors.forename: W B
authors.initials: WB
authors.lastname: Eggleston
authors.forename: G
authors.initials: G
authors.lastname: Fu
authors.forename: J K
authors.initials: JK
authors.lastname: Stewart
mesh_terms: D000818:Animals; D002531:Cerebellum / Q000737:chemistry*; D007031:Hypothalamus / Q000737:chemistry*; D008297:Male; D008526:Medulla Oblongata / Q000737:chemistry; D010625:Phenylethanolamine N-Methyltransferase / Q000235:genetics*; D016133:Polymerase Chain Reaction / Q000379:methods; D011149:Pons / Q000737:chemistry; D012333:RNA, Messenger / Q000032:analysis*; D051381:Rats; D017207:Rats, Sprague-Dawley; D014158:Transcription, Genetic
chemical_list: D012333:RNA, Messenger; D010625:Phenylethanolamine N-Methyltransferase