[Hereditary amyloidosis].
Clinical aspects of hereditary amyloidoses are very diverse, and they pose many diagnostic problems to the physician. Biochemical and genetic aspects are also various. Several proteins are implicated in these hereditary diseases: transthyretin, apolipoprotein A1, gelsolin, fibrinogen alpha chain and lysozyme. Studies on structural changes induced by the mutations in these proteins should bring new data relevant to our understanding of the amyloidogenic process. Familial mediterranean fever is a hereditary disease of the inflammatory reaction which is associated with AA amyloidosis.
Grateau
G
G
Service de médecine interne, L'Hôtel-Dieu, Paris.
D000686:Amyloidosis / Q000175:diagnosis / Q000235:genetics* / Q000378:metabolism / Q000628:therapy; D010505:Familial Mediterranean Fever / Q000175:diagnosis / Q000235:genetics; D006801:Humans; D011228:Prealbumin / Q000032:analysis / Q000235:genetics
D011228:Prealbumin
Amyloses héréditaires.