[Effect of collateral circulation on myocardial perfusion using thallium-201].
BACKGROUND
The influence of collateral circulation (CC) on thallium-201 myocardial uptake was studied in 69 patients with coronary artery disease who underwent a coronary angiography.


METHODS
According to Cohen and Rentrop a CC of 2nd and 3rd degree only was considered. A stress-early redistribution 201Tl scintigraphic protocol was utilized. The images were divided into five segments in each projection; the segments with higher uptake were considered as normal (100%). 1035 segments were analyzed and each segment was related to the donor artery on the basis of the 201Tl and angiographic evaluation. Patients were distinguished in single or multi-vessel disease with or without CC. In collateralized segments related to occluded or functionally more severe coronary stenosis, a somewhat significant prevalence of normal thallium-201 perfusion was observed, while in the non collateralized segments a higher prevalence of irreversible thallium defects was observed.


CONCLUSIONS
The data suggest that CC is one of the factors responsible for the presence of normal scintigraphic images in patients with severe coronary stenosis or complete occlusion.
Hoffmann
E
E
Facoltà di Medicina e Chirurgia, Cattedra di Cardiologia, Università degli Studi, Palermo.
Assennato
P
P
Candela
B
B
Macaluso
L
L
Alcamisi
G P
GP
D000790:Angiocardiography / Q000379:methods; D003097:Collateral Circulation; D003327:Coronary Disease / Q000000981:diagnostic imaging*; D005080:Exercise Test; D006801:Humans; D011877:Radionuclide Imaging; D013794:Thallium Radioisotopes
D013794:Thallium Radioisotopes
Influenza del circolo collaterale sulla perfusione miocardica al tallio-201.