title: [Pell-Nicol, a medicinal toothpaste].
abstract: A medicinal toothpaste based on an atomized extract obtained out of sulfurous mud of Nicolina Iassy (a natural organic-mineral complex) has been formulated and physico-chemically characterized. The optimal formula has been chosen corresponding to following parameters: aspect, colour, taste, smell; weight/tube (65 g +/- 5%); Dentine Abrasion Value (D. A. V.) = 30; pH = 6.95-7.42; foaming capability of foam, in minutes = 0.40-0.60; residue on the sieve (g% = 0.09); heavy metals content; abrasive substances; g% = 32-37 at least; sodium chloride g% = 0.30 at least; firmness time = 30 sec. Also it have been effectuated rheological measurements and dynamic viscosity. The medicinal toothpaste Pell-Nicole presents a plastic behaviour with thixotropic character, which confers a good stability in time, an adequate firmness and comparable properties with others marketed products. The therapeutical effects have been tested, such as the antimicrobial and anti-inflammatory actions. The medicinal dentifrice toothpaste Pell-Nicole is recommended for gum affections, superficial chronic inflammatory forms, deep paradontopathies, as well as for a proper dental hygiene.
authors.affiliation: Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.
authors.forename: I
authors.initials: I
authors.lastname: Popovici
authors.forename: C
authors.initials: C
authors.lastname: Caraman
authors.forename: A
authors.initials: A
authors.lastname: Stefanache
authors.forename: M
authors.initials: M
authors.lastname: Cojocaru
authors.forename: S
authors.initials: S
authors.lastname: Braha
authors.forename: C
authors.initials: C
authors.lastname: Filipovici
authors.forename: C
authors.initials: C
authors.lastname: Tăpceanu
mesh_terms: D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000627:therapeutic use*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D004341:Drug Evaluation; D006801:Humans; D008903:Minerals / Q000737:chemistry / Q000627:therapeutic use*; D010510:Periodontal Diseases / Q000628:therapy; D014100:Toothpastes / Q000032:analysis / Q000627:therapeutic use*
chemical_list: D000893:Anti-Inflammatory Agents; D008903:Minerals; D014100:Toothpastes
vernacular_title: Pell-Nicol, pasta de dinţi medicinală.