[Characterization of a protein related to Bet v 1, the major birch pollen antigen, from cells of the Madagascar periwinkle. Universal presence of proteins of this type among higher plants].
In this work we present the characterisation of a gene that codes for a protein of 17 kDa, in in vitro cultures of a plant with ornamental and pharmaceutical properties, the Madagascan periwinkle, (Catharanthus roseus [L] G. DON). This protein is very close to the principal allergen of birch and also to allergens isolated from or demonstrated in some foods such as celery, parsley, apple tree, peas, asparagus and potato, but it has no allergenic characteristics.
Carpin
S
S
Laboratoire de Biologie Moléculaire et Biochimie Végétale, Faculté de Pharmacie de Tours.
Hamdi
S
S
Rideau
M
M
D000485:Allergens; D052179:Antigens, Plant; D016384:Consensus Sequence; D016207:Cytokines / Q000494:pharmacology; D018744:DNA, Plant / Q000235:genetics; D008970:Molecular Weight; D005810:Multigene Family; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification*; D010945:Plants, Edible / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D011058:Pollen / Q000276:immunology; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity; D014197:Trees
D000485:Allergens; D052179:Antigens, Plant; D016207:Cytokines; D018744:DNA, Plant; D010940:Plant Proteins; C061312:Bet v 1 allergen, Betula
Caractérisation d'une protéine apparentée à Bet v 1, l'allergène majeur du pollen de Bouleau, dans des cellules de Pervenche de Madagascar. Présence ubiquitaire de ce groupe de protéines chez les végétaux supérieurs.