Gluconeogenesis and glycogenolysis in fluoride-treated rats.
Intraperitonial administration of 10 mg fluoride (NaF)/kg body weight resulted in hyperglycemia in rats. Role of gluconeogenesis and glycogenolysis in this hyperglycemic response was evaluated. Results of the study indicate that the fluoride induced hyperglycemia is mainly due to increased hepatic glycogenolysis.
Varadacharyulu
N C
NC
Department of Biochemistry, Sri Krishnadevaraya University, Anantapur, India.
Rao
P R
PR
D000818:Animals; D005943:Gluconeogenesis / Q000187:drug effects*; D006868:Hydrolysis; D008112:Liver Glycogen / Q000378:metabolism*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012969:Sodium Fluoride / Q000494:pharmacology*
D008112:Liver Glycogen; D012969:Sodium Fluoride