title: [Pregnancy and delivery in the patients with spina bifida--report of 5 cases].
abstract: BACKGROUND
  Because of improvement in the management for life-threatening complications of spina bifida, quality of life in the patient has become better and pregnancy is becoming more common problem in adolescent and adult female patients. In this paper, we reported patients with spina bifida who became pregnant and delivered a baby.
  
  
  METHODS
  There were 6 deliveries from 5 patients. Mean patient age at the first pregnancy was 27.6 years (ranged from 26 to 32 years). Four patients had undergone surgical managements before pregnancy, of whom 1 had augmentation cystoplasty. Urological and obstetrical conditions during the pregnancy were analyzed.
  
  
  RESULTS
  Upper urinary tract deterioration which was transient, was observed in 3 pregnancies. Serum BUN and creatinine levels remained stable throughout pregnancy in 4 patients. Pyelonephritis complicated 3 of 6 pregnancies. Delivery was vaginal in 4 and by cesarean section in 2. There were 7 obstetrical complications, which consisted of premature labor (2), uterine inertia (2), cephalo pelvic disproportion (2) and hydramnios (1). There were no significant anomalies in the newborns of these patients.
  
  
  CONCLUSIONS
  To achieve successful pregnancy and delivery in the patient with spina bifida, careful urological and obstetrical observation for the potential complications is needed.
authors.affiliation: Department of Urology, Hoshigaoka Koseinenkin Hospital.
authors.forename: M
authors.initials: M
authors.lastname: Yamamoto
authors.forename: K
authors.initials: K
authors.lastname: Yamada
authors.forename: N
authors.initials: N
authors.lastname: Hirata
authors.forename: Y
authors.initials: Y
authors.lastname: Kawata
authors.forename: A
authors.initials: A
authors.lastname: Hirayama
authors.forename: H
authors.initials: H
authors.lastname: Kashiwai
authors.forename: H
authors.initials: H
authors.lastname: Momose
authors.forename: T
authors.initials: T
authors.lastname: Shiomi
authors.forename: T
authors.initials: T
authors.lastname: Suemori
authors.forename: O
authors.initials: O
authors.lastname: Natsume
authors.forename: Y
authors.initials: Y
authors.lastname: Hirao
mesh_terms: D000328:Adult; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D007668:Kidney / Q000503:physiopathology; D007743:Labor, Obstetric; D011247:Pregnancy; D011248:Pregnancy Complications; D016135:Spinal Dysraphism / Q000503:physiopathology / Q000601:surgery