[Prevention of cardiovascular risk in menopause women: role of ovarian hormones].
Women receiving estrogen replacement therapy after menopause have a reduced risk of cardiovascular and cerebrovascular mortality when compared to untreated controls. Estrogens are thought to protect women primarily through an effect on lipid metabolism. However estrogen-induced increase of HDL-cholesterol and decrease of total and LDL-cholesterol appear to account only in part for the protective effect of ovarian hormones. Direct effects of estrogens on the arterial wall appear to contribute to the over-all cardiovascular benefits.
Rosano
G M
GM
Dipartimento di Cardiologia, Ospedale San Raffaele, Roma.
Leonardo
F
F
Ricci
S
S
Serra
G B
GB
Chierchia
S L
SL
D002318:Cardiovascular Diseases / Q000517:prevention & control*; D004730:Endothelium, Vascular / Q000187:drug effects / Q000502:physiology; D015914:Estrogen Replacement Therapy; D004967:Estrogens / Q000494:pharmacology / Q000502:physiology; D005260:Female; D005947:Glucose / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D008593:Menopause; D012307:Risk Factors; D014655:Vascular Resistance / Q000187:drug effects / Q000502:physiology
D004967:Estrogens; D005947:Glucose
La prevenzione del rischio cardiovascolare nella donna in menopausa: ruolo degli ormoni ovarici.