title: Reproductive performance and three-dimensional ultrasound volume determination of polycystic ovaries following laparoscopic ovarian drilling.
abstract: OBJECTIVE
  To evaluate the changes in ovarian volume and the reproductive outcome after laparoscopic treatment of polycystic ovaries (PCOS) in clomiphene-resistant anovulatory women.
  
  
  METHODS
  A prospective study of women undergoing laparoscopic treatment of polycystic ovaries. Ultrasound examination for three-dimensional (3D) volume determination was performed before and after surgery.
  
  
  METHODS
  University teaching hospital.
  
  
  METHODS
  Thirty-four women with polycystic ovarian syndrome who failed to ovulate with clomiphene citrate and who subsequently underwent laparoscopic ovarian drilling.
  
  
  METHODS
  Laparoscopic ovarian drilling and three-dimensional ultrasound examination.
  
  
  METHODS
  Cumulative probability of conception and changes in ovarian volume.
  
  
  RESULTS
  Ovulation rate after the procedure was 30/34 (88.2%). Using Life Table Analysis, the cumulative probability of conception at 12 months follow-up was 70% (median, 8.1 months). The preoperative ovarian volume was 12.2 +/- 1.8 cm3 and 1 week after surgery it was 13.6 +/- 1.5 cm3. The ovarian volume 3 weeks after surgery, 6.9 +/- 1.3 cm3, was significantly smaller than that before surgery.
  
  
  CONCLUSIONS
  Laparoscopic treatment of polycystic ovaries in women with clomiphene-resistant PCOS is associated with an ovulation rate of 88.2% and a cumulative pregnancy rate of 70% at 12 months. It appears also that laparoscopic ovarian drilling may result in a transient increase, with a subsequent significant reduction, in ovarian volume.
authors.affiliation: Royal Victoria Hospital, Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada.
authors.forename: T
authors.initials: T
authors.lastname: Tulandi
authors.forename: K
authors.initials: K
authors.lastname: Watkin
authors.forename: S L
authors.initials: SL
authors.lastname: Tan
mesh_terms: D000328:Adult; D004598:Electrosurgery; D005260:Female; D005306:Fertilization; D005500:Follow-Up Studies; D006801:Humans; D007091:Image Processing, Computer-Assisted; D010535:Laparoscopy / Q000379:methods*; D010053:Ovary / Q000000981:diagnostic imaging* / Q000502:physiology / Q000601:surgery*; D010060:Ovulation; D011085:Polycystic Ovary Syndrome / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D011184:Postoperative Period; D011247:Pregnancy; D018873:Pregnancy Rate; D011446:Prospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D014463:Ultrasonography