Enantioseparation of atropisomeric 1,1'-binaphthyl-2,2'-diyl hydrogen phosphate in capillary electrophoresis by using di- and oligosaccharides as chiral selectors: di- and oligosaccharide chiral selectors in capillary electrophoresis.
Twelve different disaccharides and a series of noncyclic malto- and cello-oligosaccharides were used as chiral selectors in capillary electrophoresis (CE). Most saccharides resolved the enantiomers of atropisomeric 1,1'-binaphthyl-2,2'-diyl hydrogen phosphate (BDHP) depending on the type (alpha or beta) and position of the linkage between monosaccharides. The effect of chain length of malto- and cello-oligosaccharides on enantioseparation of BDHP was also investigated. The nature of cations in background electrolytes affected significantly the separation of BDHP enantiomers.
Chankvetadze
B
B
Department of Applied Chemistry, School of Engineering, Nagoya University, Japan.
Saito
M
M
Yashima
E
E
Okamoto
Y
Y
D002240:Carbohydrate Sequence; D004110:Diltiazem / Q000737:chemistry; D004187:Disaccharides / Q000737:chemistry; D019075:Electrophoresis, Capillary; D008320:Maltose / Q000737:chemistry; D008969:Molecular Sequence Data; D009281:Naphthalenes / Q000737:chemistry*; D009844:Oligosaccharides / Q000737:chemistry*; D010755:Organophosphates / Q000737:chemistry*; D013237:Stereoisomerism
D004187:Disaccharides; D009281:Naphthalenes; D009844:Oligosaccharides; D010755:Organophosphates; C107195:1,1'-binaphthyl-2,2'-diyl hydrogen phosphate; D008320:Maltose; D004110:Diltiazem