title: [Blood component separation with gravity filtration: production of leukocyte-depleted erythrocyte concentrates].
abstract: In this study a leukocyte-depleted red-cell concentrate (RCC) was prepared by a new plasma separation filter separating by gravity. This separation filter and a leukocyte depletion filter were integrated in a 4-blood-bag system. The filtered RCC was characterized, the RCC was stored for 6 weeks, and tests to evaluate the quality of the stored RCC were performed every week. The leukocyte contamination of the RCC was (0.59 +/- 0.28 microliter-1) immediately after filtration. Compared with conventionally prepared RCC, at the end of the 6-week storage period low concentrations of LDH (86.0 +/- 5.5 U/l), K+ (36.6 +/- 6.4 mmol/l) and free hemoglobin (101.0 +/- 12.4 mg/100 ml) in the supernatant were determined.
authors.affiliation: Abteilung Hämostaseologie und Transfusionsmedizin, Max-Planck-Institut für physiologische und klinische Forschung, Kerckhoff-Klinik, Bad Nauheim, Deutschland.
authors.forename: U
authors.initials: U
authors.lastname: Taborski
authors.forename: J
authors.initials: J
authors.lastname: Kollig
authors.forename: G
authors.initials: G
authors.lastname: Müller-Berghaus
mesh_terms: D016238:Cytapheresis / Q000295:instrumentation / Q000379:methods*; D017707:Erythrocyte Transfusion; D004912:Erythrocytes; D005374:Filtration / Q000295:instrumentation / Q000379:methods; D006112:Gravitation; D006400:Hematocrit; D006801:Humans; D007962:Leukocytes
vernacular_title: Blutkomponentenseparation mittels Schwerkraftfiltration: Herstellung eines leukozytendepletierten Erythrozytenkonzentrates.