title: The role of light intensity, irradiation time and photoactive substance concentration in photodynamic therapy of tumors in preclinical research.
abstract: The role of physical parameters such as light intensity, irradiation time, light wave-length and photoactive substance concentration during photodynamic therapy is discussed. Optimal values for all these parameters were determined in a well defined biological model based on the treatment of CMC-2 fibrosarcoma implanted in the right hind leg of CBA/HZgr mice.
authors.affiliation: Sestre Milosrdnice University Hospital, Zagreb, Croatia.
authors.forename: M
authors.initials: M
authors.lastname: Doko
authors.forename: A
authors.initials: A
authors.lastname: Varc
authors.forename: M L
authors.initials: ML
authors.lastname: Urin
authors.forename: S
authors.initials: S
authors.lastname: Borović
authors.forename: H E
authors.initials: HE
authors.lastname: Zorc
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D017323:Dihematoporphyrin Ether / Q000008:administration & dosage*; D005354:Fibrosarcoma / Q000188:drug therapy*; D008027:Light; D051379:Mice; D008808:Mice, Inbred CBA; D009368:Neoplasm Transplantation; D010778:Photochemotherapy; D011829:Radiation Dosage; D013997:Time Factors
chemical_list: D000970:Antineoplastic Agents; D017323:Dihematoporphyrin Ether