title: In vivo evaluation of [123I]-8-[4-[2-(5-iodothienyl)]-4-oxobutyl]-3-methyl-1-phenyl-1,3 ,8-tri azaspiro[4.5]decan-4-one as a potential dopamine D2 receptor radioligand for SPECT.
authors.affiliation: Department of Radiology, Duke University Medical Center, Durham, NC 27710, USA.
authors.forename: R N
authors.initials: RN
authors.lastname: Waterhouse
authors.forename: J T
authors.initials: JT
authors.lastname: Gotsick
authors.forename: G W
authors.initials: GW
authors.lastname: Kabalka
authors.forename: M M
authors.initials: MM
authors.lastname: Goodman
authors.forename: J C
authors.initials: JC
authors.lastname: O'Brien
mesh_terms: D000818:Animals; D001921:Brain / Q000378:metabolism; D007093:Imidazoles / Q000378:metabolism* / Q000493:pharmacokinetics; D007457:Iodine Radioisotopes; D008297:Male; D011869:Radioligand Assay; D019275:Radiopharmaceuticals / Q000378:metabolism* / Q000493:pharmacokinetics; D051381:Rats; D017208:Rats, Wistar; D017448:Receptors, Dopamine D2 / Q000378:metabolism* / Q000502:physiology; D013141:Spiro Compounds / Q000378:metabolism* / Q000493:pharmacokinetics; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: C111014:8-(4-(2-(5-iodothienyl))-4-oxobutyl)-3-methyl-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one; D007093:Imidazoles; D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals; D017448:Receptors, Dopamine D2; D013141:Spiro Compounds