title: Individual T cells hold unexpected clues to the nature of anergy and memory.
abstract: The primary interest of our laboratory is understanding how the signals that a T cell receives influence its behavior during an immune response. Recently, we have focused our attention on the examination of T cell responses at an individual cell level. This article outlines our approach, presents our initial findings, and discusses the implications of these findings relative to our current models of T cell activation.
authors.affiliation: Department of Microbiology/Immunology, University of Pennsylvania, Philadelphia, USA.
authors.forename: A D
authors.initials: AD
authors.lastname: Wells
authors.forename: L A
authors.initials: LA
authors.lastname: Turka
mesh_terms: D000818:Animals; D006801:Humans; D007156:Immunologic Memory; D008213:Lymphocyte Activation; D015398:Signal Transduction / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*