Evaluation of the quality of HLA antibodies in placental blood.
Two groups of blood samples, placental blood and female donor blood, were shown to have a frequency of 16.4 and 1.5% of anti-human leucocyte antigen (HLA) antibodies respectively. The specificities and qualities of these antibodies were further characterized by their relative coefficient (r) values and strength indices (SIs). Most had an r value of approximately one, but their SIs varied from 41 to 100%. Among these two groups, nine samples gave very strong and definite results (r = 1 and SI = 100%). Data analysis revealed that the qualities of the two groups were comparable. However, the antibody positive rate was higher in placental blood samples than that in donor blood samples.
Huang
Y T
YT
Taichung Blood Centre, Chinese Blood Services Foundation, Taiwan.
Hsieh
Y S
YS
Phan
M C
MC
Wang
L
L
D000906:Antibodies / Q000097:blood*; D000918:Antibody Specificity; D001782:Blood Donors; D000939:Epitopes; D005069:Evaluation Studies as Topic; D005260:Female; D006680:HLA Antigens / Q000276:immunology*; D006801:Humans; D010920:Placenta / Q000098:blood supply / Q000276:immunology*; D011237:Predictive Value of Tests; D011247:Pregnancy
D000906:Antibodies; D000939:Epitopes; D006680:HLA Antigens