[Therapeutic approach in sarcoma of corpus uteri].
The results of treatment of 419 patients with endometrial sarcoma are presented. Five-year survival was 42.7% and it appeared to depend on histological pattern substantially: leimyosarcoma--49.5; endometrial stromal sarcoma--43.5; mixed mesodermal tumors--40.2% (carcinosarcoma included--26.4%). With localized tumors (stage I) of all histological patterns, survival was 3 times (58.9%) that in cases of cervix uteri involvement (19.4%). The recommendations for treatment of endometrial sarcoma are given: uterine extirpation with adnexa in patients with leimyosarcoma and a modified extended extirpation of the uterus for mixed mesodermal tumors. Radiotherapy is recommended for all patterns of tumor, except for leimyosarcoma. Adjuvant chemotherapy will increase the chances of better prognosis.
Bokhman
Ia V
IaV
Prof. N.N.Petrov Research Institute of Oncology, Ministry of Health of the RF, St.Petersburg.
Urmancheeva
A F
AF
Gershanovich
M L
ML
Zel'dovich
D R
DR
Kutusheva
G F
GF
D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D016889:Endometrial Neoplasms / Q000628:therapy*; D005260:Female; D006801:Humans; D007890:Leiomyosarcoma / Q000628:therapy*; D018199:Mixed Tumor, Mesodermal / Q000628:therapy*; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D014594:Uterine Neoplasms / Q000628:therapy*
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