title: [Rejuvenation of autologous blood preserved by washing in glucose- adenine- phosphate- and citrate-containing solution].
abstract: Outdated red cell concentrates (RCC-SAGM) were washed with a chloride-free, glucose-adenine-phosphate-citrate preservation solution. After resuspension of the red cells in this solution a hypothermic storage for additional 63 days was performed. Quality parameters (2,3-DPG, glucose, lactose, free hemoglobin, pH, chloride, pO50, shape quality index, filtration index) of the preserved red blood cells became normal within 7-11 days after the rejuvenation procedure. The data prove that a rejuvenation of outdated blood by a simple washing procedure allows a post-storage time of 21 days.
authors.affiliation: Institut für Transfusionsmedizin, Universitätsklinikum Charité, Humboldt-Universität zu Berlin, Deutschland.
authors.forename: G
authors.initials: G
authors.lastname: Matthes
authors.forename: E
authors.initials: E
authors.lastname: Richter
authors.forename: U
authors.initials: U
authors.lastname: Tofoté
authors.forename: I
authors.initials: I
authors.lastname: Pawlow
authors.forename: W
authors.initials: W
authors.lastname: Kucera
authors.forename: D
authors.initials: D
authors.lastname: Lerche
mesh_terms: D000225:Adenine; D015415:Biomarkers; D001793:Blood Preservation / Q000379:methods* / Q000592:standards; D001804:Blood Transfusion, Autologous / Q000379:methods* / Q000592:standards; D002951:Citrates; D004912:Erythrocytes; D005947:Glucose; D006801:Humans; D010710:Phosphates; D011786:Quality Control; D012996:Solutions
chemical_list: D015415:Biomarkers; D002951:Citrates; D010710:Phosphates; D012996:Solutions; D005947:Glucose; D000225:Adenine
vernacular_title: Rejuvenation von Eigenblutkonserven durch Waschen mit glukose-adenin-phosphat-citrathaltiger Lösung.