title: [Acetylcholinesterase activity and catecholamine content in nerve fibers of the thymus gland and spleen in white rats at remote time after chronic exposure to physical factors and administration of interleukin-1 beta].
abstract: Acetylcholinesterase (AChE) activity and catecholamine (CA) content in nerve fibres of the thymus and spleen of white rats were studied 6 months after prolonged combined exposure to ionizing radiation and heat and after application of interleukin-1 beta (IL-1 beta). Combined action of the physical factors induced a certain decrease in AChE activity and increase in CA content in both organs. Application of the cytokine to animals exposed to radiation and heat elicited a more pronounced decrease in AChE in these lymphoid organs and increase, especially in the spleen, in CA. The results suggest about enhanced responsiveness of the autonomic nervous system to IL-1 beta animals which had been long before exposed to prolonged combined action of radiation and heat.
authors.affiliation: Institute of Physiology, Academy of Sciences of Belarus, Minsk.
authors.forename: T Ia
authors.initials: TIa
authors.lastname: Danilova
authors.forename: P P
authors.initials: PP
authors.lastname: Murzënok
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism*; D000818:Animals; D001341:Autonomic Nervous System / Q000503:physiopathology; D002395:Catecholamines / Q000378:metabolism*; D003627:Data Interpretation, Statistical; D006358:Hot Temperature / Q000009:adverse effects*; D007375:Interleukin-1 / Q000008:administration & dosage*; D008297:Male; D009412:Nerve Fibers / Q000201:enzymology / Q000378:metabolism* / Q000528:radiation effects; D010783:Photometry; D011833:Radiation Injuries, Experimental / Q000276:immunology* / Q000503:physiopathology; D051381:Rats; D013154:Spleen / Q000294:innervation / Q000378:metabolism / Q000528:radiation effects*; D013950:Thymus Gland / Q000294:innervation / Q000378:metabolism / Q000528:radiation effects*; D013997:Time Factors
chemical_list: D002395:Catecholamines; D007375:Interleukin-1; D000110:Acetylcholinesterase
vernacular_title: Aktivnost' atsetilkholinéstgerazy i soderzhanie katekholaminov v nervnykh voloknakh timusa i selezenki belykh krys v otdalennye sroki posle khronicheskogo deĭstviia fizicheskikh faktorov i vvedeniia interleĭkina-1beta.