title: Peak flow rate changes in O3 exposed children: spirometry vs miniWright flow meters.
abstract: We compared "miniWright" peak flow (mWPF) readings with spirometric peak expiratory flow rates (PEFR) in 91 children, aged 8-15, exposed to ambient air at a summer camp in northwestern New Jersey. mWPF measurements immediately preceded spirometry, and mWPF-PEFR differences were regressed on spirometric PEFR by child. The ratio (mWPF-PEFR)/PEFR (mean +/- SE) was -0.027 +/- 0.028 (n = 91) (NS). When subdivided into PEFR ranges, the ratios were: -0.089 +/- 0.060 (n = 17) for 2-<4 Liters/second (Lps) (p = 0.04), -0.019 +/- 0.038 (n = 50) for 4-<6 Lps (NS); and -0.000 +/- 0.044 (n = 24) for 6-<8 Lps (NS). The mWPF values were also regressed on the average ozone (O3) concentration in the previous hour, by child. The mWPF response for O3 was -6.63 +/- 0.76 mL/sec/ppb, compared to -6.78 +/- 0.73 mL/sec/ppb O3 for PEFR. Thus: 1) mWPF, with an overall underestimation of approximately 2%, is a useful surrogate for spirometric values of PEFR (although, for the smallest children studied, it underestimated peak flows by approximately 9%), and 2) the portable miniWright peak flow meter is a convenient and effective tool for characterizing changes in PEFR associated with exposures to ambient O3.
authors.affiliation: New York University Medical Center, Nelson Institute of Environmental Medicine, Tuxedo 10987, USA. lippmann@charlotte.med.nyu.edu
authors.forename: M
authors.initials: M
authors.lastname: Lippmann
authors.forename: D M
authors.initials: DM
authors.lastname: Spektor
mesh_terms: D000293:Adolescent; D000397:Air Pollution / Q000032:analysis*; D002138:Calibration; D002648:Child; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D008297:Male; D010126:Ozone; D010366:Peak Expiratory Flow Rate; D015203:Reproducibility of Results; D013147:Spirometry
chemical_list: D010126:Ozone