title: Synthesis and antimicrobial activity of some new anilino benzimidazoles.
abstract: A series of 2-(anilino or 2,6-dichloroanilino)-1,5(6)-disubstituted-1H-benzimidazoles (1-13) were prepared by reaction of several 2-chloro- or 2-chloromethyl-1H-benzimidazoles with aniline derivatives. The prepared compounds were screened for their in vitro antibacterial and antifungal activities. Compounds 2, 8, and 9 exhibited the best activity.
authors.affiliation: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Tunçbilek
authors.forename: H
authors.initials: H
authors.lastname: Göker
authors.forename: R
authors.initials: R
authors.lastname: Ertan
authors.forename: R
authors.initials: R
authors.lastname: Eryigit
authors.forename: E
authors.initials: E
authors.lastname: Kendi
authors.forename: N
authors.initials: N
authors.lastname: Altanlar
mesh_terms: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001562:Benzimidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects; D013329:Structure-Activity Relationship
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D001562:Benzimidazoles