title: [Stem cell apheresis--experiences in children].
abstract: Stem cell apheresis, as a means to support patients during aplasia, has become an important support in the management of patients with various malignant diseases in need for heavy therapeutic regimens. Progress in this field is due, among other reasons, to better knowledge of pathophysiology in haematopoiesis and of the functioning of cytokines. Furthermore, the technical feasibility of apheresis has been improved to such an extent as to allow for collection of a stem cell-containing fraction almost in pure form. Our experience with stem cell apheresis is relatively short but includes also children between the ages of 1 and 21 years (median: 5 1/2 years). Whereas the clinical results have been published elsewhere, we here report our experience in terms of safety, using the Fresenius AS 104 machine.
authors.affiliation: Hämatologisches Zentrallabor der Universität, Schweiz.
authors.forename: U
authors.initials: U
authors.lastname: Nydegger
authors.forename: J
authors.initials: J
authors.lastname: Muff
authors.forename: K
authors.initials: K
authors.lastname: Walter
authors.forename: A
authors.initials: A
authors.lastname: Tobler
authors.forename: K
authors.initials: K
authors.lastname: Leibundgut
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D016238:Cytapheresis / Q000009:adverse effects / Q000379:methods; D016207:Cytokines / Q000502:physiology; D006410:Hematopoiesis; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells; D006801:Humans; D007223:Infant; D012449:Safety
chemical_list: D016207:Cytokines
vernacular_title: Stammzellapherese--Berner Erfahrungen bei Kindern.