Porphyria cutanea tarda and hematologic malignancy--a report of 4 cases.
Porphyria cutanea tarda has been reported in association with a variety of myeloproliferative and lymphoproliferative disorders, suggesting a possible association between these conditions. We describe four patients presenting within a 12 month period with sporadic porphyria cutanea tarda shortly following the diagnosis of hematologic malignancy. A review of the literature and evidence supportive of a causal association are presented.
McKenna
D B
DB
Department of Dermatology, Beaumont Hospital, Dublin, Ireland.
Browne
M
M
O'Donnell
R
R
Murphy
G M
GM
D000368:Aged; D005260:Female; D019337:Hematologic Neoplasms / Q000150:complications*; D006801:Humans; D017495:Hyperpigmentation / Q000209:etiology; D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications / Q000188:drug therapy; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000188:drug therapy; D008232:Lymphoproliferative Disorders / Q000150:complications; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications / Q000188:drug therapy; D009196:Myeloproliferative Disorders / Q000150:complications; D010257:Paraneoplastic Syndromes / Q000188:drug therapy / Q000209:etiology*; D017119:Porphyria Cutanea Tarda / Q000188:drug therapy / Q000209:etiology*
D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains