title: Research notes: Immunohistochemical observations in the ceca of chickens infected with Salmonella enteritidis phage type four.
abstract: One-day-old specific-pathogen-free White Leghorn chicks were inoculated orally with Salmonella enteritidis phage type 4 to study adhesion and invasion of the ceca by immunohistochemistry. Positive staining bacilli were associated with the epithelial surface and were present in the lumen of the cecal crypts. They were observed in the interstitial tissue and in the cytoplasm of macrophage-like cells in the lamina propria. A granulomatous nodule containing positive staining bacilli was present in the submucosa of the cecum of one bird at 14 d after inoculation.
authors.affiliation: Department of Pathology, Bacteriology and Poultry Diseases, University of Gent, Merelbeke, Belgium. Miek.Desmidt@rug.ac.be
authors.forename: M
authors.initials: M
authors.lastname: Desmidt
authors.forename: R
authors.initials: R
authors.lastname: Ducatelle
authors.forename: F
authors.initials: F
authors.lastname: Haesebrouck
mesh_terms: D000818:Animals; D001422:Bacterial Adhesion; D002432:Cecum / Q000382:microbiology* / Q000473:pathology; D002645:Chickens; D007150:Immunohistochemistry; D007413:Intestinal Mucosa / Q000382:microbiology* / Q000473:pathology; D012481:Salmonella Infections, Animal / Q000382:microbiology / Q000473:pathology*; D012477:Salmonella enteritidis / Q000145:classification / Q000302:isolation & purification* / Q000502:physiology