title: [Control of blood transfusion malaria in an endemic and in a non-endemic region in Brazil].
abstract: The aim of the present work was to establish appropriate criteria for screening of donor blood from regions with distinct Malaria epidemiological characteristics. Three locations with different screening criteria were studied: São Paulo, SP (with no vectorial transmission), Belém, PA (with low active transmission) and Matupá and Peixoto de Azevedo, MT (with high active transmission). The Malaria parasite--Plasmodium sp--was searched for by "thick film", QBC Test and antigen Immunofluorescence test, and was not detected in any of the samples. There was, however, a great variation in the positivity of anti-plasmodial antibodies, as determined by IIF-IgG anti-P. vivax and -P. falciparum, between accepted donors in the 3 studied locations and between rejected and accepted donors in São Paulo (1.98% accepted, 22.3% rejected--p < 0.01) and Belém (17.2% accepted, 58.3% rejected--p < 0.01). These data endorse the use of the applied clinical and epidemiological screening. In Matupá and Peixoto de Azevedo, where there was no rejected donor, the serological positivity was 80.6%. We, therefore, consider that the Malaria screening in blood banks should follow clinical and epidemiological criteria suitable to each region. The laboratorial screening techniques should then detect either the parasites (thick film/QBC Test or the parasite antigens.
authors.affiliation: Fundação Pró-Sangue/Hemocentro de São Paulo (FPS/HSP), Brasil.
authors.forename: A
authors.initials: A
authors.lastname: Sáez-Alquézar
authors.forename: A M
authors.initials: AM
authors.lastname: Ramos
authors.forename: S M
authors.initials: SM
authors.lastname: Di Santi
authors.forename: M S
authors.initials: MS
authors.lastname: Branquinho
authors.forename: K
authors.initials: K
authors.lastname: Kirchgatter
authors.forename: I A
authors.initials: IA
authors.lastname: Cordeiro
authors.forename: M
authors.initials: M
authors.lastname: Murta
authors.forename: J C
authors.initials: JC
authors.lastname: Saraiva
authors.forename: S G
authors.initials: SG
authors.lastname: Oliveira
authors.forename: M G
authors.initials: MG
authors.lastname: Bochetti
authors.forename: J A
authors.initials: JA
authors.lastname: Pirolla
authors.forename: D
authors.initials: D
authors.lastname: Guerzoni
authors.forename: D A
authors.initials: DA
authors.lastname: Chamone
mesh_terms: D001782:Blood Donors / Q000145:classification; D001938:Brazil / Q000453:epidemiology; D006801:Humans; D008288:Malaria / Q000097:blood / Q000453:epidemiology / Q000517:prevention & control* / Q000635:transmission; D015995:Prevalence; D065227:Transfusion Reaction; D014218:Triage
vernacular_title: Controle da malária transfusional em região endêmica e não endêmica do Brasil.