title: [Effect of hydroxylated pyrimidine derivatives on activities of thiamine-dependent enzymes and some parameters of lipid metabolism in mice].
abstract: It has been found that hydroxylated pyrimidine derivatives actively participate in metabolic proceeds related to functioning of vitamin B1-dependent enzymes (transketolase, 2-oxo acid dehydrogenase). Hydroxypyrimidines also induce a significant increase in the levels of total lipids and cholesterol in the mice liver, not changing the phospholipid content.
authors.forename: D A
authors.initials: DA
authors.lastname: Oparin
authors.forename: B I
authors.initials: BI
authors.lastname: Gorenshteĭn
authors.forename: L M
authors.initials: LM
authors.lastname: Karaedova
authors.forename: E E
authors.initials: EE
authors.lastname: Naruta
authors.forename: S V
authors.initials: SV
authors.lastname: Zabrodskaia
authors.forename: T V
authors.initials: TV
authors.lastname: Rudiak
authors.forename: V E
authors.initials: VE
authors.lastname: Akat'ev
authors.forename: F S
authors.initials: FS
authors.lastname: Larin
mesh_terms: D000818:Animals; D002784:Cholesterol / Q000378:metabolism; D005260:Female; D006900:Hydroxylation; D007655:Ketoglutarate Dehydrogenase Complex / Q000378:metabolism*; D050356:Lipid Metabolism; D051379:Mice; D010743:Phospholipids / Q000378:metabolism; D011743:Pyrimidines / Q000737:chemistry / Q000494:pharmacology*; D011768:Pyruvate Dehydrogenase Complex / Q000378:metabolism*; D014174:Transketolase / Q000378:metabolism*
chemical_list: D010743:Phospholipids; D011743:Pyrimidines; D011768:Pyruvate Dehydrogenase Complex; D002784:Cholesterol; D007655:Ketoglutarate Dehydrogenase Complex; D014174:Transketolase
vernacular_title: Vliianie gidroksilirovannykh proizvodnykh pirimidina na aktivnost' tiaminzavisimykh fermentov i nekotorye pokazateli obmena lipidov u mysheĭ.