title: [The in vitro biological behavior of TiNb30 alloy treated with hydroxyapatite and tricalcium phosphates].
abstract: An in vitro study has been carried out in different cell systems to determine the biological response of TiNb30 alloy before and after a surface treatment with hydroxyapatite (HA) and tricalcium phosphate (TCP) by the sol-gel method. TiNb30 pure Ti induce favorable cell viability with respect to pure Ni showing a high cytotoxic effect. After surface treatment with HA or HA-TCP mixtures, no difference in cell proliferation can be observed between amorphous and cristalline forms. However, HA decreases (75 +/- 15%) and HA-TCP mixtures increase (133 +/- 11%) significantly cell proliferation compared with controls.
authors.affiliation: Groupe de Recherches sur les Biomatériaux, Faculté de Médecine, Lille, France.
authors.forename: I
authors.initials: I
authors.lastname: Floquet
authors.forename: A
authors.initials: A
authors.lastname: Ralison
authors.forename: E
authors.initials: E
authors.lastname: Eisenbarth
authors.forename: A
authors.initials: A
authors.lastname: Iost
authors.forename: J
authors.initials: J
authors.lastname: Breme
authors.forename: H F
authors.initials: HF
authors.lastname: Hildebrand
mesh_terms: D000497:Alloys / Q000737:chemistry / Q000494:pharmacology*; D001672:Biocompatible Materials / Q000494:pharmacology*; D002130:Calcium Phosphates / Q000737:chemistry / Q000494:pharmacology*; D016923:Cell Death / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D003460:Crystallization; D017886:Durapatite / Q000737:chemistry / Q000494:pharmacology*; D004847:Epithelial Cells / Q000187:drug effects; D005782:Gels; D006801:Humans; D008422:Materials Testing; D009532:Nickel / Q000737:chemistry / Q000494:pharmacology; D009556:Niobium / Q000737:chemistry; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D000497:Alloys; D001672:Biocompatible Materials; D002130:Calcium Phosphates; D005782:Gels; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; D009556:Niobium; C485838:calcium phosphate, monobasic, anhydrous; D009532:Nickel; D017886:Durapatite; C020243:calcium phosphate; D014025:Titanium; C485829:calcium phosphate, dibasic, anhydrous
vernacular_title: Le comportement biologique in vitro d'un alliage TiNb30 traité avec hydroxyapatite et phosphates tricalciques.