title: [Malignant myoepithelioma associated with in situ and invasive ductal carcinoma. Description of a case and review of the literature].
abstract: A case of malignant myoepithelioma of the breast, associated with in situ and invasive carcinoma NOS is described. Myoepithelial differentiation was demonstrated with immunohistochemistry and electron microscopy. The tumour affected the left breast of a 72 year old lady. The patient had been treated with quadrantectomy with axillary dissection, followed by radiotherapy. At the time of diagnosis no local or distant metastases were found. Bone, pulmonary and cerebral metastases appeared 28 months after treatment. Malignant myoepitheliomas share histological and immunohistochemical features with monophasic sarcomatoid carcinomas. Comparison and and possible relationship with monophasic sarcomatoid carcinomas is discussed.
authors.affiliation: Sezione di Anatomia, Istologia e Citopatologia M. Malpighi, Università di Bologna, Ospedale Bellaria.
authors.forename: F
authors.initials: F
authors.lastname: Scarpellini
authors.forename: L
authors.initials: L
authors.lastname: Usellini
authors.forename: M P
authors.initials: MP
authors.lastname: Foschini
mesh_terms: D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology*; D002278:Carcinoma in Situ / Q000473:pathology*; D018270:Carcinoma, Ductal, Breast / Q000473:pathology*; D002454:Cell Differentiation; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D009208:Myoepithelioma / Q000473:pathology*; D009362:Neoplasm Metastasis; D009378:Neoplasms, Multiple Primary / Q000473:pathology*
vernacular_title: Mioepitelioma maligno associato a carcinoma duttale in situ ed invasivo NAS. Descrizione di un caso e revisione della letteratura.