title: [The anatomicopathological considerations in the clinical study of malignant non-Hodgkin's lymphomas in children].
abstract: There have been studied 78 cases with abdominal LMNH diagnosis, treated at the "Sf. Maria" Hospital of Iaşi, during the period 1970-1994. The microscopic exam has placed emphasis on the following two important aspects: (i) morphological diagnosis based on standard morphological methods, using conventional staining; (ii) immunohistochemical diagnosis, using monoclonal antibodies CD20, CD3; CD68, E29--for 18 cases. The cases investigated immunohistochemically permitted the identification of the lymphoid tumoral cells for the B/T line and tumoral macrophages, as well as the differential diagnosis with undifferentiated carcinomas. A direct correlation between a certain symptom and the disease could not be determined, although all the gastro-intestinal symptomatic elements have been taken into account. This fact reconfirmed the important role played by the anatomo-pathological exam in establishing the diagnosis and stage of the disease. Consequently the gastro-intestinal lymphomas are particular clinical entities, the investigation of which requires an interdisciplinary approach.
authors.affiliation: Disciplina de Histologie, Universitatea de Medicină şi Farmacie, Iaşi.
authors.forename: I D
authors.initials: ID
authors.lastname: Căruntu
authors.forename: D
authors.initials: D
authors.lastname: Mihăilă
authors.forename: M
authors.initials: M
authors.lastname: Mănescu
authors.forename: G
authors.initials: G
authors.lastname: Dobrescu
authors.forename: B
authors.initials: B
authors.lastname: Savu
mesh_terms: D000293:Adolescent; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007223:Infant; D008228:Lymphoma, Non-Hodgkin / Q000145:classification / Q000378:metabolism / Q000473:pathology*; D008297:Male; D009336:Necrosis
vernacular_title: Consideraţii anatomo-patologice pe marginea studiului clinic al limfoamelor maligne non-hodgkiniene la copil.