title: [Palladium-containing compounds possess radiation-protective properties and enhance adaptive response of CFUs to radiation].
abstract: Efasol and potassium tetrachloropalladate being injected into mice prior to irradiation with a dose of 150 sGy increase the colony forming activity of animals bone marrow cells transplanted in lethally irradiated recipient mice. The palladium presence in such compounds is supposed to be a reason of radioprotection. Upon the combined application of potassium tetrachloropalladate and irradiation of mice with an adaptive dose of 5 sGy a potentiation of individual effect of each separate agent to increase CFUs resistance against the consequent irradiation was observed.
authors.affiliation: Medical Radiological Research Centre of Russian Academy of Medical Science, Obninsk.
authors.forename: T N
authors.initials: TN
authors.lastname: Semenets
authors.forename: O V
authors.initials: OV
authors.lastname: Semina
authors.forename: I A
authors.initials: IA
authors.lastname: Efimenko
authors.forename: N A
authors.initials: NA
authors.lastname: Ivanova
authors.forename: A M
authors.initials: AM
authors.lastname: Poverennyĭ
mesh_terms: D000220:Adaptation, Biological; D000818:Animals; D001854:Bone Marrow Cells / Q000187:drug effects* / Q000528:radiation effects*; D016026:Bone Marrow Transplantation; D005260:Female; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D010165:Palladium / Q000494:pharmacology*; D011829:Radiation Dosage; D011837:Radiation-Protective Agents / Q000494:pharmacology*; D013997:Time Factors
chemical_list: D011837:Radiation-Protective Agents; C030174:tetrachloropalladium; D010165:Palladium
vernacular_title: Palladiĭsoderzhashchie soedineniia obladaiut radioprotektivnymi svoĭstvami i usilivaiut adaptivnyĭ otvek KOEs k radiatsionnomu vozdeĭstviiu.