title: [The treatment of rectal cancer--the optimizing possibilities].
abstract: The authors studies 280 rectal cancers treated in the first surgical clinic of Iaşi in the period 1981-1994. Although surgery is the main treatment of these tumors, it cannot be and it must be not used alone. Surgery must be associated with radio- and chemotherapy, because is the only way possible to increase the number of resections for rectal tumors and the survival rate. For the 263 tumors operated the resectability was 73, 5%: Milles's operation 101 (36, 7%), Dixon's operation 81 (30, 79%), other operation 91 (33, 11%). We consider that Dixon's operation is the best choice for the tumors in the stages A and B of Dukes classifications. Preoperative radiotherapy can influence the tumor volume (downstaging) and decrease local recurrences to about 10-15%. Surgery alone must be practiced only in emergencies. Postoperative chemotherapy is mandatory and it reduces local recurrences and delays metastasis evolution.
authors.affiliation: Clinica I-a Chirurgicală, Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.
authors.forename: M
authors.initials: M
authors.lastname: Chifan
authors.forename: N
authors.initials: N
authors.lastname: Dănilă
authors.forename: D
authors.initials: D
authors.lastname: Niculescu
authors.forename: E
authors.initials: E
authors.lastname: Târcoveanu
authors.forename: S
authors.initials: S
authors.lastname: Georgescu
authors.forename: O
authors.initials: O
authors.lastname: Epure
authors.forename: D
authors.initials: D
authors.lastname: Andronic
authors.forename: M R
authors.initials: MR
authors.lastname: Găleşanu
authors.forename: E
authors.initials: E
authors.lastname: Carasevici
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000453:epidemiology; D018714:Radiotherapy, Adjuvant; D012004:Rectal Neoplasms / Q000150:complications / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D012007:Rectum / Q000473:pathology / Q000601:surgery; D012383:Romania / Q000453:epidemiology
vernacular_title: Tratamentul cancerului rectal--posibilităţi de optimizare.