Assessment of genome damage in occupational exposure to ionising radiation and ultrasound.
The mutagenic effects of low doses of radiation on occupationally exposed subjects were studied on lymphocyte culture using two methods: analysis of structural chromosome aberrations and micronucleus assay. The results obtained in subjects exposed to ionising radiation alone were compared to those exposed to both ionising radiation and ultrasound. A correlation between the total number of chromosome aberrations and distribution of micronuclei in the genome of somatic cells show higher deviation in the group exposed to X-ray and ultrasound than in the group exposed to X-rays alone. The degree of genome damage in occupational exposure to X-rays and ultrasound were discussed.
Vera
G V
GV
Institute for Medical Research and Occupational Health, Ksaverska, Zagreb, Croatia.
Aleksandra
F
F
Dragan
K
K
Andrija
H
H
D000328:Adult; D002869:Chromosome Aberrations; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D008214:Lymphocytes / Q000187:drug effects; D008297:Male; D015162:Micronucleus Tests; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D014463:Ultrasonography / Q000009:adverse effects*; D014965:X-Rays / Q000009:adverse effects*