[Increased levels of erythropoietin in the initial phase of acute myocardial infarction].
BACKGROUND
It's know that cardiopulmonary function affects the kidney perfusion and that erythropoietin (EPO) release depends on it. We want to determine the plasma level of EPO in the acute phase of myocardial infarction (AMI).


METHODS
A transversal trial was carried out in 37 male patients with AMI aged between 31 and 84. We studied the following variables: cardiovascular risk factors, time lapse from beginning of symptoms until hospital arrival, transcutaneous oxygen saturation (ST02) and EPO plasma levels. 16 healthy males were used as control group.


RESULTS
Patients with AMI have different EPO levels than control group (25/37 vs 0/16) (18.90 +/- 8.43 mUI/ml vs 9.70 +/- 3.48 mUI/ml respectively p < 0.001). Hyperintense patients have higher EPO levels than normotense ones (18.53 +/- 8.28 mUI/ml vs 12.88 +/- 7.29 mUI/ml p < 0.05). Hypercholesterolemic patients have higher EPO level than normocholesterolemic ones (19 +/- 8.88 mUI/ml vs 12.40 +/- 6.75 mUI/ml p < 0.01). There were no difference between smokers and no smokers. We didn't find correlation between time lapse and EPO levels.


CONCLUSIONS
The trial remarks EPO levels increase during the initial phase of AMI and it is higher in hypertensive and hypercholesterolemic patients.
Antón Martínez
J
J
Servicio de Medicina Interna, Unidad de Cardiología, Hospital Campo Arañuelo, Navalmoral de la Mata, Cáceres.
Ojeda Ortego
J
J
González Blanco
P
P
Gutiérrez Sampedro
N
N
Palma Nieto
J C
JC
León García
L A
LA
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D004921:Erythropoietin / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood*; D013997:Time Factors
D004921:Erythropoietin
Elevación de la eritropoyetina en la fase inicial del infarto agudo de miocardio.