[Protein A immunoadsorption treatment of patients with refractory autoimmune thrombopenia].
Eight patients with chronic immunothrombocytopenia (ITP) who had failed at least one alternative therapy were treated with extracorporeal immunoadsorption. Two of the 8 patients responded to the treatment with a stable increase in platelet counts, but both of them had to be continuously treated with corticosteroids. Side effects of the treatment with extracorporeal immunoadsorption were musculoskeletal pain, nausea, vomiting, tachycardia, purpura, fatigue, and others.
Petersen
N
N
Institut für Blutspendewesen, Städtische Kliniken Dortmund, Deutschland.
Bremer
K
K
Hammad-Zulfughari
D
D
Kemper
J
J
Grüntjes-Prinsen
G
G
Hansmann
E
E
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D005112:Extracorporeal Circulation / Q000009:adverse effects; D006801:Humans; D007163:Immunosorbent Techniques / Q000009:adverse effects; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000628:therapy*; D013205:Staphylococcal Protein A
D000305:Adrenal Cortex Hormones; D013205:Staphylococcal Protein A
Protein-A-Immunadsorptionsbehandlung bei Patienten mit therapierefraktärer Autoimmunthrombopenie.