[The connection between ultrastructural synaptic plasticity and the number of ribosomes in the dendritic terminals studied in a cell model of conditioning in the rat neocortex].
The dependence was studied of the ultrastructural changes in postsynaptic densities of axodendritic synapses on the size of postsynaptic ribosomal aggregates. A positive correlation was established between the thickness of postsynaptic densities and the number of ribosomes. The role of dendritic mRNA is discussed and the possible mechanisms underlying rapid local protein synthesis in a modification of postsynaptic components which have been observed in case of combined application of two neurotransmitters to the neocortex of rats.
Khludova
G G
GG
Lomonosov State University, Moscow.
D000818:Animals; D016009:Chi-Square Distribution; D003213:Conditioning, Psychological / Q000502:physiology*; D003712:Dendrites / Q000502:physiology* / Q000648:ultrastructure; D005260:Female; D008959:Models, Neurological; D009044:Motor Cortex / Q000502:physiology / Q000648:ultrastructure; D019579:Neocortex / Q000502:physiology* / Q000648:ultrastructure; D009473:Neuronal Plasticity / Q000502:physiology*; D017729:Presynaptic Terminals / Q000502:physiology* / Q000648:ultrastructure; D012333:RNA, Messenger / Q000502:physiology; D051381:Rats; D012269:Ribosomal Proteins / Q000096:biosynthesis; D012270:Ribosomes / Q000502:physiology* / Q000648:ultrastructure; D013569:Synapses / Q000502:physiology* / Q000648:ultrastructure
D012333:RNA, Messenger; D012269:Ribosomal Proteins
Issledovanie sviazi mezhdu ul'trastrukturnoĭ sinapticheskoĭ plastichnost'iu i chislom ribosom v dendritnykh okonchaniiakh na kletochnoĭ modeli obuslovlivanii v neokortekse krys.