Parvovirus-induced pancytopenia in a child with acquired haemolytic anaemia.
A 14-year-old boy, with acquired haemolytic anaemia secondary to paravalvular leak from a prosthetic aortic valve, presented with severe pancytopenia. Subsequent investigation showed serological evidence of recent parvovirus B19 infection. The patient required transfusion and subsequently improved rapidly, with maintenance of pre-infective haemoglobin levels. To our knowledge this is the first reported case in which infection with parvovirus has caused pancytopenia in an acquired chronic mechanical haemolytic anaemia.
Myers
B
B
Department of Clinical and Laboratory Haematology, University Hospital, Nottingham, UK.
Dolan
G
G
D000293:Adolescent; D000743:Anemia, Hemolytic / Q000628:therapy / Q000821:virology*; D003131:Combined Modality Therapy; D017707:Erythrocyte Transfusion; D006801:Humans; D008297:Male; D010198:Pancytopenia / Q000628:therapy / Q000821:virology*; D010322:Parvoviridae Infections / Q000150:complications* / Q000628:therapy