title: Diffuse bony uptake of thallium-201-chloride in the granulocyte colony-stimulating factor-producing lung carcinoma.
abstract: Diffuse uptake of 201TI in the axial bone is reported in a patient with large cell carcinoma of the lung who showed leukocytosis and an increased concentration of granulocyte colony-stimulating factor (G-CSF) in plasma. The abnormal bony uptake of 201TI disappeared in association with normalization of the elevated plasma G-CSF level after complete tumor resection. The production of G-CSF was confirmed by immunoperoxidase staining of the tumor tissue.
authors.affiliation: Department of Internal Medicine, Nishi-Kobe Medical Center, Kobe, Japan.
authors.forename: R
authors.initials: R
authors.lastname: Takeuchi
authors.forename: K
authors.initials: K
authors.lastname: Kasagi
authors.forename: H
authors.initials: H
authors.lastname: Ohta
authors.forename: J
authors.initials: J
authors.lastname: Konishi
mesh_terms: D001842:Bone and Bones / Q000000981:diagnostic imaging*; D002289:Carcinoma, Non-Small-Cell Lung / Q000150:complications / Q000000981:diagnostic imaging* / Q000378:metabolism; D002951:Citrates; D005708:Gallium; D005710:Gallium Radioisotopes; D016179:Granulocyte Colony-Stimulating Factor / Q000096:biosynthesis*; D006801:Humans; D007964:Leukocytosis / Q000150:complications; D008175:Lung Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013793:Thallium; D013794:Thallium Radioisotopes
chemical_list: D002951:Citrates; D005710:Gallium Radioisotopes; D019275:Radiopharmaceuticals; D013794:Thallium Radioisotopes; D016179:Granulocyte Colony-Stimulating Factor; C027549:thallium chloride; D013793:Thallium; D005708:Gallium; C103850:gallium citrate