Bilateral zonular cataract associated with the mitochondrial cytopathy of Pearson syndrome.
OBJECTIVE
To report a child with the mitochondrial cytopathy of Pearson syndrome and zonular cataract.


METHODS
Case report. We describe a 6-year-old boy with Pearson syndrome.


RESULTS
At age 3 years, the boy developed secondary strabismus caused by bilateral zonular cataract. Subsequently, he underwent successful bilateral cataract extraction with intraocular lens implantation. Postoperative visual acuity with best correction was RE, 20/25 and LE, 20/40.


CONCLUSIONS
Children with Pearson syndrome should be examined ophthalmologically to rule out zonular cataract and possible amblyopia. Mitochondrial cytopathies such as Pearson syndrome should be included in the differential diagnosis of congenital and early juvenile cataract.
Cursiefen
C
C
Department of Ophthalmology, University Eye Hospital, Friedrich-Alexander-University Erlangen-Nürnberg, Germany. claus.cursiefen@augen.med.uni-erlangen.de
Küchle
M
M
Scheurlen
W
W
Naumann
G O
GO
D000756:Anemia, Sideroblastic / Q000150:complications* / Q000473:pathology; D001855:Bone Marrow Diseases / Q000150:complications* / Q000473:pathology; D002386:Cataract / Q000209:etiology*; D002387:Cataract Extraction; D002648:Child; D004272:DNA, Mitochondrial / Q000235:genetics; D017353:Gene Deletion; D006130:Growth Disorders / Q000150:complications* / Q000473:pathology; D006801:Humans; D019654:Lens Implantation, Intraocular; D008297:Male; D008928:Mitochondria / Q000473:pathology*; D013577:Syndrome
D004272:DNA, Mitochondrial