[Activation of blood lymphocytes in lung cancer patients with polyclonal mitogens].
The lymphocyte proliferative response to PHA, Con A and PWM was studied in patients with lung tumors (stage I-IV) and other histological types. Disorders in the mitogen-induced lymphocyte activation were identified in more advanced tumors. Certain peculiarities of lymphocyte proliferative activity were found to be determined by histological pattern and localization. A method of evaluation of blasttransformation consequences with due account of lymphocyte functional activity in cancer patients is suggested.
Oleĭnik
E K
EK
Institute of Biology, Karelian Research Center of Russian Academy of Sciences, Petrozavodsk.
Bakhlaev
I E
IE
Ageenko
A I
AI
D000328:Adult; D000368:Aged; D002455:Cell Division / Q000187:drug effects; D003208:Concanavalin A / Q000494:pharmacology; D005260:Female; D006801:Humans; D037102:Lectins / Q000494:pharmacology; D008175:Lung Neoplasms / Q000276:immunology* / Q000473:pathology; D008213:Lymphocyte Activation / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D008934:Mitogens / Q000494:pharmacology*
D037102:Lectins; D008934:Mitogens; D003208:Concanavalin A
Aktivatsiia limfotsitov krovi bol'knykh rakom lëgkogo polyklonal'nymi mitogenami.