[Mucoepidermoid carcinoma of the submandibular gland after high-dose radioiodine therapy: case report and review of the literature].
Case report of a 42 year old female, who received 14th-20th year of life six radioiodine therapies with altogether 19.2 GBq131I because of a papillary thyroid carcinoma. 17 years after the last therapy, she developed a histologically proven chronic radiogenic sialadenitis of the left submandibular gland. Further four years later, the right submandibular gland has been extirpated because of a mucoepidermoid carcinoma with infiltration of a regionary lymphatic node. Review of the previous published secondary-malignancies of the salivary glands after high-dose radioiodine therapies.
Henze
M
M
Abteilung für Nuklearmedizin der Radiologischen Universitätsklinik Heidelberg, Deutschland.
Hittel
J P
JP
Elser
H
H
D000328:Adult; D018277:Carcinoma, Mucoepidermoid / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D002291:Carcinoma, Papillary / Q000532:radiotherapy*; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000009:adverse effects*; D008207:Lymphatic Metastasis; D009381:Neoplasms, Radiation-Induced / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D019275:Radiopharmaceuticals / Q000009:adverse effects*; D013365:Submandibular Gland Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D013964:Thyroid Neoplasms / Q000532:radiotherapy*; D014057:Tomography, X-Ray Computed
D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals
Mukoepidermoid-Karzinom der Glandula Submandibularis nach hochdosierter Radioiodtherapie: Fallpräsentation und Literaturübersicht.