[Effect of the flavonoid quercetin on the detoxication function of the liver].
Experiments in vivo have shown that introduction of quercetin leads to the decrease of microsomal oxidation intensity and makes more active the enzymes responsible for creation of conjugates in cytosolic and microsomal fractions of the animal liver. It is supposed that such an action of flavonoid is justified for the latter to be used as a method for correction of harmful substances metabolism under various deviations from the detoxication process connected with the proceeding of pathological processes in the organism.
Sivachenko
O Ie
OIe
Ruda
N V
NV
Markina
O A
OA
D000818:Animals; D003600:Cytosol / Q000187:drug effects / Q000378:metabolism; D005982:Glutathione Transferase / Q000378:metabolism; D006168:Guinea Pigs; D008658:Inactivation, Metabolic; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008862:Microsomes, Liver / Q000187:drug effects / Q000378:metabolism; D011794:Quercetin / Q000494:pharmacology*; D005723:gamma-Glutamyltransferase / Q000378:metabolism
D011794:Quercetin; D005723:gamma-Glutamyltransferase; D005982:Glutathione Transferase
Vplyv flavonoïdu kvertsetynu na dezintoksykatsiĭ funktsiiu pechinky.