[In vitro and in vivo biocompatibility of stainless steel as a function of surface treatments: roughness and surfacing with hydroxyapatite].
The in vitro tests on cell viability reveal a favorable position for steel and hydroxyapatite (HA)? However, the roughness induces a negative effect on cell proliferation. Sandblasting of the stainless steel considerably decreased cell number compared with the polished substrate. HA showed a better percentage of proliferation in spite of the surface effect compared with controls. For in vivo biocompatibility, intramuscular implants revealed localized inflammatory reactions for the HA treated stainless steel but nor for the untreated alloy.
Bataille
L
L
Groupe de Recherche sur les Biomatériaux, Faculté de Médecine de Lille, France.
Judas
D
D
Rocher
P
P
Laffargue
P
P
Lecomte-Houcke
M
M
Iost
A
A
Lefevre
A
A
Hildebrand
H F
HF
D000818:Animals; D001284:Atrophy; D001672:Biocompatible Materials / Q000737:chemistry / Q000494:pharmacology; D002455:Cell Division / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002478:Cells, Cultured; D017886:Durapatite / Q000737:chemistry / Q000494:pharmacology; D004847:Epithelial Cells / Q000187:drug effects / Q000473:pathology; D005355:Fibrosis; D005549:Foreign-Body Reaction / Q000473:pathology; D015726:Giant Cells / Q000473:pathology; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D020007:Implants, Experimental; D007928:Lethal Dose 50; D008297:Male; D008422:Materials Testing; D018482:Muscle, Skeletal / Q000473:pathology / Q000601:surgery; D019919:Prosthesis Implantation; D011817:Rabbits; D013193:Stainless Steel / Q000737:chemistry / Q000494:pharmacology; D013499:Surface Properties
D001672:Biocompatible Materials; D013193:Stainless Steel; D017886:Durapatite
Biocompatibilité in vitro et in vivo de l'acier inoxydable en fonction du traitement de surface: rugosité et revêtement avec hydroxyapatite.