title: [Malignant tumors of the peripheral nerve sheath (MPNST) after irradiation].
abstract: A case of relapsed malignant tumor of the brachial plexus and its nervous roots (MPNST) was observed in a patient treated with radiotherapy for Hodgkin's disease 24 years previously. A known risk of radiation therapy is the induction of secondary neoplasms, less commonly malignant peripheral nerve sheath tumor (MPNST). The clinico-pathological features of this rare tumor are presented and the possible relationship between radiotherapy and MPNST is discussed.
authors.affiliation: Cattedra di Chirurgia Plastica e Ricostruttiva, Istituto di Anatomiae Istologia Patologica, Università di Firenze.
authors.forename: M
authors.initials: M
authors.lastname: Dini
authors.forename: A
authors.initials: A
authors.lastname: Caldarella
authors.forename: G
authors.initials: G
authors.lastname: Lo Russo
authors.forename: P
authors.initials: P
authors.lastname: Conti
mesh_terms: D000293:Adolescent; D001917:Brachial Plexus / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006689:Hodgkin Disease / Q000532:radiotherapy*; D006801:Humans; D015182:Lymphatic Irradiation / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging; D008479:Mediastinal Neoplasms / Q000473:pathology / Q000556:secondary; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009381:Neoplasms, Radiation-Induced / Q000209:etiology* / Q000473:pathology; D016609:Neoplasms, Second Primary / Q000209:etiology* / Q000473:pathology; D018319:Neurofibrosarcoma / Q000209:etiology* / Q000473:pathology / Q000556:secondary; D013117:Spinal Cord Compression / Q000209:etiology; D013125:Spinal Neoplasms / Q000150:complications / Q000473:pathology / Q000556:secondary
vernacular_title: Tumore maligno della guaina dei nervi periferici (MPNST) post-irradiazione.