Comparative study of the toxic actions of 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane and 2,2-bis(p-chlorophenyl)-1,1-dichloroethylene on the growth and respiratory activity of a microorganism used as a model.
A strain of Bacillus stearothermophilus was used as a model for a comparative study of the toxic effect of 2,2-bis(p-chlorophenyl)-1,1,1-trichloroethane and 2,2-bis(p-chlorophenyl)-1,1-dichloroethylene. Bacterial growth, the O2 consumption rate, and respiration-related enzymatic activities provided quantitative data in agreement with results reported for other systems. The use of this bacterium for screening for chemical toxicity is discussed.
Donato
M M
MM
Centro de Neurociências, Universidade de Coimbra, Portugal.
Jurado
A S
AS
Antunes-Madeira
M C
MC
Madeira
V M
VM
D002455:Cell Division / Q000187:drug effects; D003634:DDT / Q000633:toxicity*; D003633:Dichlorodiphenyl Dichloroethylene / Q000633:toxicity*; D004352:Drug Resistance, Microbial; D001411:Geobacillus stearothermophilus / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D007306:Insecticides / Q000633:toxicity*; D008954:Models, Biological; D010084:Oxidation-Reduction; D010101:Oxygen Consumption / Q000187:drug effects
D007306:Insecticides; D003633:Dichlorodiphenyl Dichloroethylene; D003634:DDT