The change to non-CFC metered dose inhalers.
The first non-chlorofluorocarbon containing (non-CFC) metered dose inhaler (MDI) (i.e. albuterol, Airomir, 3M) has been approved for marketing in over 35 countries. It is hoped by the year 2000 most MDIs will use non-CFC propellants. By the year 2005 it is likely that CFC containing MDIs will no longer be available in developed countries. This article looks at the basis for this change and how it may affect medical practice.
Rubinfeld
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Royal Melbourne Hospital, Parkville.
D000280:Administration, Inhalation; D000335:Aerosol Propellants / Q000009:adverse effects; D000420:Albuterol / Q000008:administration & dosage*; D001249:Asthma / Q000188:drug therapy*; D001315:Australia; D001993:Bronchodilator Agents / Q000008:administration & dosage*; D017402:Chlorofluorocarbons / Q000009:adverse effects; D004867:Equipment Design; D006801:Humans; D006845:Hydrocarbons, Fluorinated; D009313:National Health Programs; D009330:Nebulizers and Vaporizers / Q000592:standards*
D000335:Aerosol Propellants; D001993:Bronchodilator Agents; D017402:Chlorofluorocarbons; D006845:Hydrocarbons, Fluorinated; D000420:Albuterol