[Low-grade papillary transitional-cell carcinoma of the distal urethra with focal squamous differentiation and association with human papillomavirus types 6-11].
OBJECTIVE
To report a case of transitional cell carcinoma of the urethra associated with human papilloma virus (HPV) infection in areas of squamous differentiation of the neoplasm.


RESULTS
A 32-year-old male with a previously treated condylomata acuminatum of the prepuce presented with a verrucous lesion in the penile meatus, corresponding to well differentiated, low grade papillary transitional cell carcinoma with squamous differentiation. Histological viral expression of HPV was confirmed by in situ hybridization.


CONCLUSIONS
We emphasize the rare presentation of transitional carcinoma in the distal urethra associated with HPV infection.
Alonso
E
E
Instituto de Anatomía Patológica, Rosario, Argentina.
Maróstica
A
A
Roma
S
S
Redín
I
I
Sánchez Mazzaferri
F
F
Toffoni
C
C
D000328:Adult; D002295:Carcinoma, Transitional Cell / Q000473:pathology* / Q000821:virology; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D002472:Cell Transformation, Viral; D006801:Humans; D017403:In Situ Hybridization; D008297:Male; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000473:pathology* / Q000821:virology; D014412:Tumor Virus Infections / Q000473:pathology* / Q000821:virology; D014521:Urethra / Q000473:pathology / Q000821:virology; D014523:Urethral Neoplasms / Q000473:pathology* / Q000821:virology
Carcinoma transicional papilar, de bajo grado, de uretra distal, con diferenciación escamosa focal y asociación con virus papiloma humano, tipos 6-11.