[Interaction of Mycobacteria isolated from sarcoidosis patients with antituberculosis antibodies].
In 80% of cases, antituberculosis antibodies from the sera of patients with tuberculosis were ascertained to react in enzyme immunoassay (EIA) with antigens (ultrasound disintegrants (USDs)) of reverse mycobacteria isolated (initially) from patients with sarcoidosis. The USDs of reverse mycobacteria isolated from patients with sarcoidosis reacted in EIA with monoclonal antibodies (MAb) against M. tuberculosis complex antigens (unique and crossover). Both common and distinctive (unique) antigenic determinants were detected via MAb against different mycobacterial types by immunoblotting in the antigenic complexes of M. tuberculosis H37Rv and reverse strains isolated from patients with sarcoidosis.
Litvinov
V I
VI
Central NII of Tuberculosis PAMN, Moscow.
Chernousova
L N
LN
Safonova
S G
SG
Kalinina
O A
OA
Kulikovskaia
N V
NV
Kapina
M A
MA
Dem'ianenko
N V
NV
D000818:Animals; D000907:Antibodies, Bacterial / Q000276:immunology*; D000911:Antibodies, Monoclonal / Q000276:immunology; D000942:Antigens, Bacterial / Q000276:immunology; D003429:Cross Reactions / Q000276:immunology; D006801:Humans; D015151:Immunoblotting; D007124:Immunoenzyme Techniques; D051379:Mice; D008807:Mice, Inbred BALB C; D009169:Mycobacterium tuberculosis / Q000276:immunology* / Q000302:isolation & purification*; D012507:Sarcoidosis / Q000382:microbiology*; D013183:Sputum / Q000382:microbiology; D014397:Tuberculosis, Pulmonary / Q000276:immunology*
D000907:Antibodies, Bacterial; D000911:Antibodies, Monoclonal; D000942:Antigens, Bacterial
Vzaimodeístvie mikobakterií, bydelennykh ot bol'nykh sarkoidozom, s protivotuberkuleznymi antitelami.