Alendronate-induced esophagitis: case report of a recently recognized form of severe esophagitis with esophageal stricture--radiographic features.
Alendronate sodium, an aminobiphosphonate used primarily to treat osteoporosis in postmenopausal women, is known to cause esophagitis. A 71-year-old woman experienced severe, acute esophagitis and severe stricture of the esophagus due to oral alendronate therapy. Unlike in previous cases, she had taken alendronate for 10 months before the onset of complications and the stricture proved resistant to dilation.
Ryan
J M
JM
Department of Radiology, Massachusetts General Hospital, Boston, USA.
Kelsey
P
P
Ryan
B M
BM
Mueller
P R
PR
D000284:Administration, Oral; D000368:Aged; D019386:Alendronate / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D004106:Dilatation; D004940:Esophageal Stenosis / Q000139:chemically induced* / Q000000981:diagnostic imaging* / Q000628:therapy; D004941:Esophagitis / Q000139:chemically induced* / Q000000981:diagnostic imaging* / Q000628:therapy; D005260:Female; D006801:Humans; D015663:Osteoporosis, Postmenopausal / Q000188:drug therapy*; D011859:Radiography; D013997:Time Factors; D017211:Treatment Failure
D019386:Alendronate