[Rejuvenation of autologous blood preserved by washing in glucose- adenine- phosphate- and citrate-containing solution].
Outdated red cell concentrates (RCC-SAGM) were washed with a chloride-free, glucose-adenine-phosphate-citrate preservation solution. After resuspension of the red cells in this solution a hypothermic storage for additional 63 days was performed. Quality parameters (2,3-DPG, glucose, lactose, free hemoglobin, pH, chloride, pO50, shape quality index, filtration index) of the preserved red blood cells became normal within 7-11 days after the rejuvenation procedure. The data prove that a rejuvenation of outdated blood by a simple washing procedure allows a post-storage time of 21 days.
Matthes
G
G
Institut für Transfusionsmedizin, Universitätsklinikum Charité, Humboldt-Universität zu Berlin, Deutschland.
Richter
E
E
Tofoté
U
U
Pawlow
I
I
Kucera
W
W
Lerche
D
D
D000225:Adenine; D015415:Biomarkers; D001793:Blood Preservation / Q000379:methods* / Q000592:standards; D001804:Blood Transfusion, Autologous / Q000379:methods* / Q000592:standards; D002951:Citrates; D004912:Erythrocytes; D005947:Glucose; D006801:Humans; D010710:Phosphates; D011786:Quality Control; D012996:Solutions
D015415:Biomarkers; D002951:Citrates; D010710:Phosphates; D012996:Solutions; D005947:Glucose; D000225:Adenine
Rejuvenation von Eigenblutkonserven durch Waschen mit glukose-adenin-phosphat-citrathaltiger Lösung.