[The characteristics of the changes in the submicroscopic structure of the immunocompetent cells in the development of experimental mycobacterioses].
The electron-microscopic study of the ultrastructure of peritoneal exudate cells of laboratory animals during the development of infectious processes caused by Mycobacterium tuberculosis and atypical mycobacteria was carried out. The study revealed that in all pathological processes under study typical manifestation of cell-mediated immunity took place, characterized by microbial phagocytosis on the level of cell ultrastructure, an increase in the lysosomal activity and the exhaustion of cells involved in the process up to their destruction. These changes in processes caused by the action of the agents of different mycobacterial infections were manifested with different intensity.
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Research Institute of Epidemiology and Hygiene, Lvov, Ukraine.
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D000818:Animals; D001202:Ascitic Fluid / Q000166:cytology; D001402:B-Lymphocytes / Q000648:ultrastructure*; D006168:Guinea Pigs; D008854:Microscopy, Electron; D009165:Mycobacterium Infections, Nontuberculous / Q000473:pathology*; D009162:Mycobacterium avium; D009163:Mycobacterium bovis; D019907:Mycobacterium fortuitum; D019909:Mycobacterium kansasii; D015359:Mycobacterium scrofulaceum; D013601:T-Lymphocytes / Q000648:ultrastructure*; D013997:Time Factors; D014376:Tuberculosis / Q000473:pathology*
Osobennosti izmeneniĭ submikroskopicheskogo stroeniia immunokompetentnykh kletok pri razvitii éksperimental'nykh mikobakteriozov.