title: Development of hyperthyroidism during long term interferon therapy in a patient with chronic myelogenous leukemia: case report.
abstract: In this case report a patient with thyroid dysfunction who received chronic treatment with interferon-alpha (INF-alpha) following a diagnosis of chronic myelogenous leukemia (CML) is described. Generally INF-alpha induced dysthyroidism develops in the earlier phase of INF-alpha treatment. This is a case report of thyroid dysfunction which occurred 4 years after the patient began to receive INF-alpha administration. In addition, INF-alpha was administered to this patient for a longer period than those reported in the literature.
authors.affiliation: Department of Medical Oncology, Gülhane Military Academy, Ankara-Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Ozet
authors.forename: G
authors.initials: G
authors.lastname: Ozet
authors.forename: Z
authors.initials: Z
authors.lastname: Calişkaner
authors.forename: S
authors.initials: S
authors.lastname: Kömürcü
authors.forename: B
authors.initials: B
authors.lastname: Oztürk
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000139:chemically induced*; D016898:Interferon-alpha / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000188:drug therapy*; D008875:Middle Aged
chemical_list: D000970:Antineoplastic Agents; D016898:Interferon-alpha