Translational fidelity: error-prone versus hyper-accurate ribosomes.
Decoding mRNA is a multistep process involving the RNA and protein components of the ribosome, and external factors; little is known about the mechanism, however. New evidence suggests that a central region in small ribosomal RNA switches between two helices in translation to maintain translational fidelity.
von Ahsen
U
U
Research Institute of Molecular Pathology, Vienna, Austria. ahsen@nt.imp.univie.ac.at
D009690:Nucleic Acid Conformation; D014176:Protein Biosynthesis; D012335:RNA, Ribosomal / Q000737:chemistry; D012336:RNA, Ribosomal, 16S / Q000737:chemistry*; D012343:RNA, Transfer / Q000737:chemistry*; D012269:Ribosomal Proteins / Q000737:chemistry; D012270:Ribosomes / Q000737:chemistry*
D012335:RNA, Ribosomal; D012336:RNA, Ribosomal, 16S; D012269:Ribosomal Proteins; D012343:RNA, Transfer