Chromosomal mosaicisms during prenatal diagnosis.
Chromosomal mosaicism during prenatal diagnosis has been a major concern. Nondisjunctional events can lead to mosaicism in a number of ways, including failure of chromosomal pairing, failure to separate, anaphase lag and abnormal segregation. We provide a concise review on various types of mosaicism with their clinical significance.
Verma
R S
RS
Division of Genetics, The Long Island College Hospital-SUNY Health Science Center, Brooklyn, N.Y. 11201-5514, USA.
Kleyman
S M
SM
Conte
R A
RA
D000649:Amniocentesis; D015193:Chorionic Villi Sampling; D002869:Chromosome Aberrations / Q000175:diagnosis* / Q000209:etiology / Q000235:genetics; D025063:Chromosome Disorders; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009030:Mosaicism / Q000175:diagnosis* / Q000235:genetics; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*; D014960:X Chromosome