title: Monitoring of pH and PCO2 in children using the Paratrend 7 in a peripheral vein.
abstract: OBJECTIVE
  To determine the accuracy of the Paratrend 7 monitor inserted into a peripheral vein in providing continuous measurements of PCO2 and pH in children with respiratory failure.
  
  
  METHODS
  In a prospective, case series at a University based PICU in a tertiary referral hospital and following informed consent, the Paratrend 7 intra-arterial blood gas monitoring system was inserted through a peripheral intravenous cannula. When clinically indicated, an arterial blood gas (ABG) was obtained. The values of pH and PCO2 from the Paratrend 7 and the ABG were compared using linear regression analysis and Bland-Altman analysis.
  
  
  RESULTS
  Seventeen ABGs were obtained in the 4 patients. PaCO2 ranged from 29 to 51 mmHg and the pH values from 7.16 to 7.50. Linear regression analysis for the: Paratrend 7 pH vs the ABG pH resulted in an r = 0.9678 and an r2 = 0.9367 (P < 0.0001). Linear regression analysis for the Paratrend 7 CO2 vs ABG CO2 resulted in an r = 0.8273 and an r2 = 0.6845 (P = 0.01). Using a Bland and Altman analysis, the bias +/- precision of the PCO2 values was 3 +/- 1.4 and 0.036 +/- 0.02 for the pH values.
  
  
  CONCLUSIONS
  The pH and PCO2 values obtained from the Paratrend 7 monitor provide a clinically acceptable correlation with arterial values.
authors.affiliation: Department of Child Health, University of Missouri, Columbia 65212, USA.
authors.forename: J D
authors.initials: JD
authors.lastname: Tobias
authors.forename: D J
authors.initials: DJ
authors.lastname: Meyer
authors.forename: M A
authors.initials: MA
authors.lastname: Helikson
mesh_terms: D000293:Adolescent; D001158:Arteries; D015982:Bias; D002245:Carbon Dioxide / Q000097:blood*; D002406:Catheterization, Peripheral / Q000295:instrumentation*; D002408:Catheters, Indwelling; D002648:Child; D002675:Child, Preschool; D003422:Critical Care; D005260:Female; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D016014:Linear Models; D008297:Male; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D011446:Prospective Studies; D012131:Respiratory Insufficiency / Q000097:blood*; D012680:Sensitivity and Specificity; D014680:Veins
chemical_list: D002245:Carbon Dioxide