title: [High malignant B-cell non-Hodgkin lymphoma of the heart: intravital diagnosis by transesophageal echocardiography controlled biopsy].
abstract: We report about a 66-year old patient with Non-Q-wave infarction in coronary artery two-vessel disease. During an echo- and transesophageal multiplane echocardiography preoperatively before a coronary artery bypass surgery a right atrium septal tumor of unknown form was discovered. The computerized axial tomography (CAT) and nuclear magnetic resonance (NMR) scans did not demonstrate extracardiac pathologic findings. A transesophageal echocardiography-guided biopsy of the right atrial septum over the vena femoralis and the right atrium enabled intra vitam a very early diagnosis of high malignant B-cell Non-Hodgkin-lymphoma without the need for thoracotomy. The diagnosis was confirmed histopathologically and immunohistochemically and early treatment with cytostatic therapy could begin. To our knowledge the transesophageal echocardiography-guided biopsy has never been described in the worldwide literature.
authors.affiliation: Krankenhaus München-Neuperlach, 2. Medizinische Abteilung/Kardiologie und Pneumologie.
authors.forename: J L
authors.initials: JL
authors.lastname: Fischer
authors.forename: D
authors.initials: D
authors.lastname: Antoni
authors.forename: J
authors.initials: J
authors.lastname: Quadbeck
authors.forename: H
authors.initials: H
authors.lastname: Kramer
authors.forename: G
authors.initials: G
authors.lastname: Tiefenböck
authors.forename: G
authors.initials: G
authors.lastname: Aschenbrenner
authors.forename: H
authors.initials: H
authors.lastname: Strohm
authors.forename: H J
authors.initials: HJ
authors.lastname: Krieg
authors.forename: C
authors.initials: C
authors.lastname: Fuchs
authors.forename: S
authors.initials: S
authors.lastname: Gross
authors.forename: M
authors.initials: M
authors.lastname: Schlemmer
authors.forename: K
authors.initials: K
authors.lastname: Nibler
authors.forename: M
authors.initials: M
authors.lastname: Garbrecht
authors.forename: L
authors.initials: L
authors.lastname: Henselmann
authors.forename: B
authors.initials: B
authors.lastname: Bültmann
mesh_terms: D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D006328:Cardiac Catheterization; D017548:Echocardiography, Transesophageal; D006325:Heart Atria / Q000000981:diagnostic imaging / Q000473:pathology; D006338:Heart Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D006346:Heart Septum / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D016393:Lymphoma, B-Cell / Q000000981:diagnostic imaging* / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000473:pathology
chemical_list: D014408:Biomarkers, Tumor
vernacular_title: Hochmalignes B-Zell-Non-Hodgkin-Lymphom des Herzens: intravitale Diagnose durch transösophageale Echokardiographie-gesteuerte Biopsie.