Randomized, controlled, clinical trial of rice versus glucose oral rehydration solutions in infants and young children with acute watery diarrhoea.
A randomized clinical trial was carried out to compare a packaged ready-to-mix rice oral rehydration solution (ORS) to the standard glucose ORS for the treatment of childhood diarrhoea. Children were of either gender, aged 3-35 months, presenting with a history of watery diarrhoea for 72 h or less. The main outcomes examined were stool output, ORS intake, duration of diarrhoea and nutritional recovery during follow-up at 16 d of illness. Stool output in the first 24 h (106 vs 107 g kg(-1)), ORS intake in clinic (93 vs 102 ml per motion) and duration of diarrhoea (88 h vs 81 h) were similar in the two treatment groups. The few episodes that became persistent were similar (2%) in the two groups. The weight gain during follow-up was similar in the two ORS groups.
Faruque
A S
AS
International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka.
Hoque
S S
SS
Fuchs
G J
GJ
Mahalanabis
D
D
D000208:Acute Disease; D000284:Administration, Oral; D002675:Child, Preschool; D003967:Diarrhea / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D003968:Diarrhea, Infantile / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D005260:Female; D005947:Glucose / Q000627:therapeutic use*; D006801:Humans; D007194:India; D007223:Infant; D008297:Male; D012275:Oryza / Q000627:therapeutic use*; D008517:Phytotherapy; D015532:Rehydration Solutions / Q000627:therapeutic use*; D016896:Treatment Outcome; D015430:Weight Gain
D015532:Rehydration Solutions; D005947:Glucose