title: [Metastatic disease of the liver: surgical perspective].
abstract: Approximately half of patients with colorectal cancer will develop hepatic metastases and it is estimated that up to 10% of that group will have resectable liver disease. Surgical resection remains the first line treatment option of metastatic liver tumors and has yielded a 20 to 40% five year survival rate. Selection of appropriate patients for resection is critical to a successful outcome. The best results are obtained in patients with isolated metastases. Factors that are associated with a poorer results are the presence of four or more lesions or a surgical margin less than 1 cm. Endocrine metastases can be resected in a palliative fashion but each case has to be individualized. This is also true for non colorectal-nonendocrine metastases. For this tumors the experience is anecdotal and confined to limited reported series. Adjuvant treatment (infusional chemotherapy and chemoembolization) can also have a role in treatment as well as cryotherapy.
authors.affiliation: Clínica de Hipertensión Portal, Instituto Nacional de la Nutrición Salvador Zubirán, México, D.F.
authors.forename: M A
authors.initials: MA
authors.lastname: Mercado
authors.forename: H
authors.initials: H
authors.lastname: Medina
authors.forename: A
authors.initials: A
authors.lastname: Rossano
authors.forename: E
authors.initials: E
authors.lastname: Acosta
authors.forename: M
authors.initials: M
authors.lastname: Rodríguez
authors.forename: C
authors.initials: C
authors.lastname: Chan
authors.forename: H
authors.initials: H
authors.lastname: Orozco
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D016461:Chemoembolization, Therapeutic; D015179:Colorectal Neoplasms; D017679:Cryotherapy; D005467:Floxuridine / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery* / Q000628:therapy; D016031:Liver Transplantation; D010166:Palliative Care; D018579:Patient Selection; D011379:Prognosis; D015996:Survival Rate
chemical_list: D000964:Antimetabolites, Antineoplastic; D005467:Floxuridine; D005472:Fluorouracil
vernacular_title: Enfermedad metastásica de hígado. Enfoque quirúrgico.