title: [Minimizing the costs of prescription of anti-infective drugs in two areas of primary health care].
abstract: BACKGROUND
  Pharmaceutical costs are the main cost item in basic health care. The need to contain health care expenditure has led to the search for alternatives in this area, one of which would be to foster a prescription policy which uses the cheapest presentation for each active principle. The aim of this study was to evaluate the amount which would be saved by prescribing the cheapest alternative from a selection of anti-infective drugs.
  
  
  METHODS
  Pharmacy prescriptions in two different health areas were analyzed using the database on turnover of pharmaceutical products for 1995. Single principle drugs with anti-infective action were selected, and for each active principle and presentation the most economic alternative was sought using the records provided by the Ministry of Health and a cost minimisation analysis was undertaken. The cost of applying this prescription policy was not considered.
  
  
  RESULTS
  Total pharmaceutical expenditure in the areas was pesetas 8.547 bn in 1995. Expenditure on selected anti-infective drugs was pesetas 522 million (6.1% of the total). The overall saving estimated was 7.63% (pesetas 39,901,778). This saving was centred on the following subgroups: penicillins, quinolones, cephalosporins and macrolides. Of potential savings identified, 75% would be achieved by prescribing the cheaper alternative of 2 active principles: amoxacillin and cyprofloxacine.
  
  
  CONCLUSIONS
  The study shows the possibility of containing expenditure in our area and offers a basis for action in this direction. It would be advisable to increase information and training for prescribers and dispensers in order to stimulate the use of the most economical alternative of each medicament prescribed, especially in cases in which there are significant margins to be saved.
authors.affiliation: Servicio de Medicina Preventiva, Hospital Miguel Servet, Zaragoza.
authors.forename: S
authors.initials: S
authors.lastname: Castán Cameo
authors.forename: F J
authors.initials: FJ
authors.lastname: García Latorre
authors.forename: J
authors.initials: J
authors.lastname: Martínez Gorostiaga
authors.forename: M J
authors.initials: MJ
authors.lastname: Sierra Moros
authors.forename: V M
authors.initials: VM
authors.lastname: Solano Bernad
authors.forename: A
authors.initials: A
authors.lastname: Peral Casado
mesh_terms: D000890:Anti-Infective Agents / Q000191:economics*; D002391:Catchment Area, Health; D003365:Costs and Cost Analysis; D011307:Drug Prescriptions / Q000191:economics*; D006801:Humans; D011320:Primary Health Care; D013030:Spain
chemical_list: D000890:Anti-Infective Agents
vernacular_title: Un estudio de minimización de costes en la prescripción de antiinfecciosos en dos areas de atención primaria.