title: Early postnatal hypoglycaemia in newborn infants of diabetic mothers.
abstract: This study found that early postnatal hypoglycaemia was mainly induced by foetal hyperinsulinaemia, in close relation to maternal hyperglycaemia, even in well-controlled pregnancies of 59 mothers with insulin-treated diabetes mellitus, 29 with insulin-dependent diabetes mellitus and 30 with gestational diabetes mellitus. Ten of the newborn children (17%) had a blood glucose concentration below 1.0 mmol l(-1) at 2 h postnatally. Cord insulin-like growth factor-I or glucagon concentrations were not related to the early decline of blood glucose.
authors.affiliation: Department of Paediatrics, Orebro Medical Centre Hospital, Sweden.
authors.forename: E
authors.initials: E
authors.lastname: Stenninger
authors.forename: J
authors.initials: J
authors.lastname: Schollin
authors.forename: J
authors.initials: J
authors.lastname: Aman
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001786:Blood Glucose / Q000032:analysis; D015331:Cohort Studies; D003922:Diabetes Mellitus, Type 1 / Q000150:complications* / Q000188:drug therapy; D016640:Diabetes, Gestational / Q000150:complications* / Q000188:drug therapy; D005260:Female; D005312:Fetal Blood / Q000378:metabolism; D005934:Glucagon / Q000032:analysis; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007003:Hypoglycemia / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D015994:Incidence; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D007334:Insulin-Like Growth Factor I / Q000032:analysis; D008297:Male; D011181:Postnatal Care; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000150:complications* / Q000188:drug therapy; D013548:Sweden / Q000453:epidemiology
chemical_list: D001786:Blood Glucose; D005934:Glucagon; D006442:Glycated Hemoglobin; D007334:Insulin-Like Growth Factor I