title: Genetic heterogeneity of strains of Neisseria meningitidis belonging to serotype 22 isolated in the Czech Republic.
abstract: Strains of Neisseria meningitidis of serogroup B isolated in the Czech Republic frequently belong to serotype 22. We analyzed the genetic relationships among strains of this serotype by using the multilocus enzyme electrophoresis technique and the polymorphism of the pilA gene. Our results indicate that these strains correspond to a highly heterogeneous population rather than to the expansion of a single clone.
authors.affiliation: National Reference Laboratory for Meningococcal Infections, NIPH, Prague, Czech Republic.
authors.forename: M
authors.initials: M
authors.lastname: Musilek
authors.forename: D
authors.initials: D
authors.lastname: Giorgini
authors.forename: N
authors.initials: N
authors.lastname: Hamadouche
authors.forename: P
authors.initials: P
authors.lastname: Kriz
authors.forename: M K
authors.initials: MK
authors.lastname: Taha
mesh_terms: D000483:Alleles; D001426:Bacterial Proteins / Q000235:genetics*; D018153:Czech Republic / Q000453:epidemiology; D004269:DNA, Bacterial / Q000032:analysis* / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics*; D036781:Fimbriae Proteins; D006801:Humans; D007527:Isoenzymes / Q000235:genetics*; D008589:Meningococcal Infections / Q000453:epidemiology / Q000235:genetics* / Q000276:immunology; D009345:Neisseria meningitidis / Q000201:enzymology / Q000235:genetics* / Q000276:immunology; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
chemical_list: D001426:Bacterial Proteins; D004269:DNA, Bacterial; D004268:DNA-Binding Proteins; D007527:Isoenzymes; D036781:Fimbriae Proteins