title: Management of oral Kaposi's sarcoma and a proposal for clinical staging.
abstract: Kaposi's sarcoma (KS) is the most common neoplastic disease in patients with disease due to human immunodeficiency virus (HIV), and oral KS (OKS) is the commonest oral neoplasia. OKS has been managed by local excision, intralesional chemotherapy regional radiotherapy, and systemic chemotherapy. Comparison between studies is difficult as the severity of oral involvement is not well defined in most studies. This paper reviews the approach to the management of OKS and also presents a proposal for the clinical staging of OKS. Clinical staging of OKS will facilitate comparisons of outcomes of treatment of OKS and improve our understanding of the natural history of the neoplasia, which has varied presentation and rates of progression.
authors.affiliation: British Columbia Cancer Agency, Vancouver, Canada.
authors.forename: J B
authors.initials: JB
authors.lastname: Epstein
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D017742:Dental Care for Chronically Ill; D006801:Humans; D015552:Injections, Intralesional; D009062:Mouth Neoplasms / Q000209:etiology / Q000473:pathology* / Q000628:therapy*; D009367:Neoplasm Staging; D010043:Outcome and Process Assessment, Health Care; D010166:Palliative Care; D010347:Patient Care Planning; D012514:Sarcoma, Kaposi / Q000209:etiology / Q000473:pathology* / Q000628:therapy*; D014747:Vinblastine / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D014747:Vinblastine