[Metastatic disease of the liver: surgical perspective].
Approximately half of patients with colorectal cancer will develop hepatic metastases and it is estimated that up to 10% of that group will have resectable liver disease. Surgical resection remains the first line treatment option of metastatic liver tumors and has yielded a 20 to 40% five year survival rate. Selection of appropriate patients for resection is critical to a successful outcome. The best results are obtained in patients with isolated metastases. Factors that are associated with a poorer results are the presence of four or more lesions or a surgical margin less than 1 cm. Endocrine metastases can be resected in a palliative fashion but each case has to be individualized. This is also true for non colorectal-nonendocrine metastases. For this tumors the experience is anecdotal and confined to limited reported series. Adjuvant treatment (infusional chemotherapy and chemoembolization) can also have a role in treatment as well as cryotherapy.
Mercado
M A
MA
Clínica de Hipertensión Portal, Instituto Nacional de la Nutrición Salvador Zubirán, México, D.F.
Medina
H
H
Rossano
A
A
Acosta
E
E
Rodríguez
M
M
Chan
C
C
Orozco
H
H
D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D016461:Chemoembolization, Therapeutic; D015179:Colorectal Neoplasms; D017679:Cryotherapy; D005467:Floxuridine / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000556:secondary* / Q000601:surgery* / Q000628:therapy; D016031:Liver Transplantation; D010166:Palliative Care; D018579:Patient Selection; D011379:Prognosis; D015996:Survival Rate
D000964:Antimetabolites, Antineoplastic; D005467:Floxuridine; D005472:Fluorouracil
Enfermedad metastásica de hígado. Enfoque quirúrgico.