title: Trace metals in urine of United States residents: reference range concentrations.
abstract: We measured 13 metals in the urine of 496 United States residents to establish reference range concentrations using inductively coupled argon plasma mass spectrometry and Zeeman graphite furnace atomic absorption spectrometry. We frequently found 8 of these analytes at detectable concentrations in urine specimens: molybdenum (in 99.8%); lead (98.8%); tin (89%); thallium (77%); antimony (73.5%); manganese (73%); cesium (71%); tungsten (70%); and platinum (69.7%). The 95th percentile concentration for molybdenum was 168 micrograms/L; concentrations ranged up to 688 micrograms/L. Lead concentrations ranged up to 67 micrograms/L, and the 95th upper percentile was 6.4 micrograms/L. Tin had 95th upper percentile of 20.1 micrograms/L. Other analytes measured at detectable concentrations included barium (in 67% of the specimens); beryllium (67%); chromium (54%); thorium (44%); and cobalt (43%). In almost every case, the 95th upper percentiles of these analytes were less than 15 micrograms/L.
authors.affiliation: Division of Environmental Health Laboratory Sciences, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA.
authors.forename: D C
authors.initials: DC
authors.lastname: Paschal
authors.forename: B G
authors.initials: BG
authors.lastname: Ting
authors.forename: J C
authors.initials: JC
authors.lastname: Morrow
authors.forename: J L
authors.initials: JL
authors.lastname: Pirkle
authors.forename: R J
authors.initials: RJ
authors.lastname: Jackson
authors.forename: E J
authors.initials: EJ
authors.lastname: Sampson
authors.forename: D T
authors.initials: DT
authors.lastname: Miller
authors.forename: K L
authors.initials: KL
authors.lastname: Caldwell
mesh_terms: D000328:Adult; D002648:Child; D003627:Data Interpretation, Statistical; D005260:Female; D006801:Humans; D008297:Male; D014131:Trace Elements / Q000652:urine*; D014481:United States
chemical_list: D014131:Trace Elements