Purification and characterization of anti-Listeria compounds produced by Geotrichum candidum.
Geotrichum candidum can produce and excrete compounds that inhibit Listeria monocytogenes. These were purified by ultrafiltration, centrifugal partition chromatography, thin-layer chromatography, gel filtration, and high-pressure liquid chromatography, and analyzed by liquid chromatography-mass spectrometry, infrared spectrometry, nuclear magnetic resonance spectrometry, and optical rotation. Two inhibitors were identified: D-3-phenyllactic acid and D-3-indollactic acid.
Dieuleveux
V
V
Laboratoire de Microbiologie Alimentaire, Institut de Recherche en Biologie Appliquée, Université de Caen, France.
Van Der Pyl
D
D
Chataud
J
J
Gueguen
M
M
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000302:isolation & purification* / Q000494:pharmacology; D007773:Lactates / Q000302:isolation & purification* / Q000494:pharmacology*; D008087:Listeria / Q000187:drug effects*; D003904:Mitosporic Fungi / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D007773:Lactates; C017648:3-phenyllactic acid