title: Cancer of the thyroid in children and adolescents.
abstract: Thyroid cancer is a rare but intriguing malignancy when it occurs in childhood and adolescence. In this retrospective study 58 young patients with thyroid cancer treated at the Rabin Medical Centre are presented. We found that thyroid carcinoma in children presented in a more advanced stage than in adults, and the incidence of regional metastases at the time of presentation is higher. Nevertheless, the biological behaviour of the tumour is more benign. We believe that near-total thyroidectomy is the treatment of choice in this age group for disease limited to the gland, and total thyroidectomy with perithyroidal neck dissection should be performed in patients with nodal disease. For follow-up, we recommend physical examination with measurement of thyroglobulin and TSH levels, ultrasound examination of the neck and chest radiography.
authors.affiliation: Department of Otolaryngology, Rabin Medical Centre, Petah Tiqva, Israel.
authors.forename: K
authors.initials: K
authors.lastname: Segal
authors.forename: A
authors.initials: A
authors.lastname: Arad-Cohen
authors.forename: S
authors.initials: S
authors.lastname: Mechlis
authors.forename: E
authors.initials: E
authors.lastname: Lubin
authors.forename: R
authors.initials: R
authors.lastname: Feinmesser
mesh_terms: D018263:Adenocarcinoma, Follicular / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D000293:Adolescent; D002291:Carcinoma, Papillary / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D018265:Carcinoma, Papillary, Follicular / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008197:Lymph Node Excision; D008297:Male; D037981:Neck Dissection; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D013965:Thyroidectomy; D013997:Time Factors
chemical_list: D007457:Iodine Radioisotopes