[Superantigens and their possible involvement in psoriasis and other diseases].
Superantigens unit products of bacterial and viral agents which, in combination with MHC cl II, are capable to stimulate a large fraction of T lymphocytes in one affected individual. This stimulation primarily interests the variable region V of beta chain of T lymphocyte receptor. Superantigens are recently isolated, characterized and they seem to be implicated in some immune diseases. The study of this superantigens gives some explanations to certain incert pathogenic mechanisms.
Nemţişor
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Policlinica, Spital Univ. Sf. Spiridon, Iaşi.
D000942:Antigens, Bacterial / Q000276:immunology*; D000956:Antigens, Viral / Q000276:immunology*; D000949:Histocompatibility Antigens Class II / Q000276:immunology; D006801:Humans; D011565:Psoriasis / Q000209:etiology / Q000276:immunology*; D018089:Superantigens / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology
D000942:Antigens, Bacterial; D000956:Antigens, Viral; D000949:Histocompatibility Antigens Class II; D018089:Superantigens
Superantigene şi implicaţii posibile ale acestora în psoriasis şi în alte afecţiuni.