[Comparison ov anti-HCV tests of the first and second generation and suggestions for a re-entry program].
After following up approximately 200,000 blood donors with 1st- and 2nd-generation anti-HCV tests the authors suggest: 1) to neglect earlier 1st-generation-positive anti-HCV results when the donor is negative in 2nd-generation ELISAs; 2) after a donation positive in a 2nd-generation test the following donation must not be used even if it is negative; a third, negative donation can be used; 3) a donor with two different donations positive in 2nd-generation ELISAs should be excluded from the donor pool.
Caspari
G
G
Institut für Medizinische Virologie, Justus-Liebig-Universität, Giessen.
Gerlich
W H
WH
Beyer
J
J
Schmitt
H
H
D001782:Blood Donors; D001803:Blood Transfusion / Q000592:standards*; D004797:Enzyme-Linked Immunosorbent Assay; D005500:Follow-Up Studies; D016174:Hepacivirus / Q000302:isolation & purification*; D006526:Hepatitis C / Q000175:diagnosis* / Q000517:prevention & control; D018937:Hepatitis C Antibodies / Q000097:blood*; D006801:Humans; D018579:Patient Selection; D011786:Quality Control
D018937:Hepatitis C Antibodies
Vergleich von Anti-HCV-Tests der 1. und 2. Generation und Vorschläge für ein Re-entry-Programm.