title: Catalysis of peroxynitrite reactions by manganese and iron porphyrins.
abstract: Kinetics and products of peroxynitrite anion O=NOO- reactions, catalyzed by water-soluble manganese and iron porphyrins, were studied under basic and neutral conditions. In the absence of organic substrates peroxynitrite decomposes catalytically to give nitrite and dioxygen as major products. Catalytic decomposition competes with direct oxidation of sulfoxide to sulfone, while phenol is catalytically nitrated in o- and p-positions. A reaction mechanism is proposed.
authors.affiliation: Laboratoire de Chimie de Coordination, CNRS, Toulouse, France. balavoin@lcc-toulouse.fr
authors.forename: G G
authors.initials: GG
authors.lastname: Balavoine
authors.forename: Y V
authors.initials: YV
authors.lastname: Geletti
authors.forename: D
authors.initials: D
authors.lastname: Bejan
mesh_terms: D000426:Alcohol Dehydrogenase; D002384:Catalysis; D005609:Free Radicals / Q000378:metabolism; D007501:Iron / Q000378:metabolism; D007700:Kinetics; D008345:Manganese / Q000494:pharmacology*; D015394:Molecular Structure; D009566:Nitrates / Q000378:metabolism*; D010100:Oxygen / Q000378:metabolism; D010636:Phenols / Q000378:metabolism; D011166:Porphyrins / Q000378:metabolism*; D013454:Sulfoxides / Q000378:metabolism; D013876:Thiophenes
chemical_list: D005609:Free Radicals; D009566:Nitrates; D010636:Phenols; D011166:Porphyrins; D013454:Sulfoxides; D013876:Thiophenes; C038166:tetramethylene sulfoxide; C039642:peroxynitric acid; D008345:Manganese; D007501:Iron; D000426:Alcohol Dehydrogenase; D010100:Oxygen