[Metabolic processes in the tissues of pregnant animals and their fetuses affected by ammonium chloride].
The acid-alkali state of blood as well as some parameters of energy, nitrogen and protein metabolism in animals at the last stage of pregnancy and in their fetuses have been studied as affected by ammonium chloride. It is shown that ammonium chloride in a dose of 0.6 g per 1 kg of the body weight that was given to duply pregnant animals per os evokes the decrease of O2 partial pressure and the increase of the amount of CO2 in the blood, stimulates the processes of ureogenesis and glycoly-sis, inhibits reactions of tissue respiration, changes redox-state of free nicotinamide coenzymes and intracellular level of inorganic phosphorus in the organism of animals at the last stage of pregnancy. Analogous changes of metabolic processes under high content of ammonium chloride in the organism are also observed in their fetuses.
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D000643:Ammonium Chloride / Q000494:pharmacology*; D000818:Animals; D002245:Carbon Dioxide / Q000097:blood; D004305:Dose-Response Relationship, Drug; D005260:Female; D005333:Fetus / Q000187:drug effects / Q000378:metabolism*; D006019:Glycolysis / Q000187:drug effects; D006863:Hydrogen-Ion Concentration; D009536:Niacinamide / Q000378:metabolism; D009584:Nitrogen / Q000378:metabolism; D010100:Oxygen / Q000097:blood; D010101:Oxygen Consumption / Q000187:drug effects; D010313:Partial Pressure; D010758:Phosphorus / Q000378:metabolism; D011247:Pregnancy; D011270:Pregnancy, Animal / Q000097:blood / Q000378:metabolism*; D051381:Rats; D017208:Rats, Wistar; D014508:Urea / Q000378:metabolism
D000643:Ammonium Chloride; D002245:Carbon Dioxide; D009536:Niacinamide; D010758:Phosphorus; D014508:Urea; D009584:Nitrogen; D010100:Oxygen
Osoblivosti metabolichnykh protsesiv v tkaninakh vagitnikh tvaryn ta ïkh plodiv pid vplivom NH4Cl