[Occurrence of D category VI in blood donors in Baden-Württemberg].
33,830 repeated donors and 9,157 first donors were screened for DVI. All D-positive first donors and the repeated donors with depressed D antigen (Du) were tested with Seraclone anti-D (IgM) that is known to be nonreactive with DIV. D-positive donors who were negative with Seraclone anti-D were further evaluated with a monoclonal IgG anti-D nonreactive with DIV. By using a D-screen panel it was attempted to type donors who were also negative with these antibodies. With this procedure, among 42,987 donors, 4 donors with DVI and 2 donors with probable DVI or closely related variants were detected. This is in agreement with previous reports from Great Britain and Australia. These donors with qualitative variants represent 2% of donors previously typed as Du and 10% of D-positive donors who were negative with Seraclone.
Wagner
F
F
Abteilung Transfusionsmedizin, Universität Ulm, Deutschland.
Wölpl
A
A
Kubanek
B
B
D000911:Antibodies, Monoclonal; D001782:Blood Donors; D005858:Germany; D006681:HLA-D Antigens / Q000097:blood* / Q000145:classification; D006801:Humans; D007074:Immunoglobulin G
D000911:Antibodies, Monoclonal; D006681:HLA-D Antigens; D007074:Immunoglobulin G
Häufigkeit der D-Kategorie VI unter Blutspendern in Baden-Württemberg.