title: [A case of unresectable advanced gastric cancer with severe obstructive jaundice responding to combined chemotherapy with 5-fluorouracil and low-dose cisplatin].
abstract: A 69-year-old male patient with gastric cancer complaining severe jaundice was readmitted for the purpose of chemotherapy. The primary tumor was unresectable, and his jaundice was gradually increasing because of the growth of tumor, so the patient was treated by combined chemotherapy with 5-fluorouracil and low-dose cisplatin for 2 courses (1 course = 4 weeks), which resulted in remarkable reduction of jaundice without any severe side effects. So, the patient could be discharged and spend a useful life for about 10 months with good quality of life. This therapy might be a useful palliative chemotherapy for cases of this kind.
authors.affiliation: First Dept. of Surgery, Kurume University School of Medicine.
authors.forename: K
authors.initials: K
authors.lastname: Yasumoto
authors.forename: M
authors.initials: M
authors.lastname: Iwamoto
authors.forename: M
authors.initials: M
authors.lastname: Hoshiko
authors.forename: S
authors.initials: S
authors.lastname: Kawabata
authors.forename: J
authors.initials: J
authors.lastname: Takeda
authors.forename: K
authors.initials: K
authors.lastname: Shirouzu
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002779:Cholestasis / Q000188:drug therapy* / Q000209:etiology; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D008297:Male; D010166:Palliative Care; D011788:Quality of Life; D013274:Stomach Neoplasms / Q000150:complications / Q000188:drug therapy*
chemical_list: D002945:Cisplatin; D005472:Fluorouracil