Styrene toxicity: an ecotoxicological assessment.
Although other aromatic compounds (e.g., benzene, toluene, polycyclic aromatic hydrocarbons (PAH), etc.) have been thoroughly studied over the years, styrene has been given little attention probably due to its lower rate of industrial use. In addition, it is less toxic than benzene and PAH, proven carcinogens. However, it is classified as a mutagen and thus potentially carcinogenic. Its main use is in the production of the polymer polystyrene and in the production of plastics, rubber, resins, and insulators. Entry into the environment is mainly through industrial and municipal discharges. In this review, the toxicological effects of styrene on humans, animals, and plants are discussed. Its mode of entry and methods of monitoring its presence are examined. Although its effects on humans and aquatic life have been studied, the data on short- or long-term exposures to plants, birds, and land animals are insufficient to be conclusive. Since exposure to workers can result in memory loss, difficulties in concentration and learning, brain and liver damage, and cancer, development of accurate methods to monitor its exposure is essential. In addition, the review outlines the present state of styrene in the environment and suggests ways to deal with its presence. It might appear that the quantities are not sufficient to harm humans, but more data are necessary to evaluate its effect, especially on workers who are regularly exposed to it.
Gibbs
B F
BF
Concordia University, Montreal, Quebec, Canada.
Mulligan
C N
CN
D000818:Animals; D002170:Canada; D002273:Carcinogens / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity*; D017753:Ecosystem; D004784:Environmental Monitoring; D006801:Humans; D008862:Microsomes, Liver / Q000378:metabolism; D009153:Mutagens / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity*; D016273:Occupational Exposure; D010969:Plastics / Q000138:chemical synthesis; D013045:Species Specificity; D020058:Styrene; D013343:Styrenes / Q000737:chemistry / Q000378:metabolism / Q000633:toxicity*; D014874:Water Pollutants, Chemical / Q000633:toxicity
D002273:Carcinogens; D009153:Mutagens; D010969:Plastics; D013343:Styrenes; D014874:Water Pollutants, Chemical; D020058:Styrene