[Effects of fatty acid amides on phosphatidylcholine hydrolysis catalyzed by phospholipase A2 in micelles].
The effect of fatty acid amides on the hydrolysis of natural phosphatidylcholine and its semisynthetic analog, dioleoyl phosphatidylcholine, catalyzed by phospholipase A2 in mixed micelles with Triton X-100 has been studied. Palmitoylamide, oleoylamide, and stearoylamide were shown to be the inhibitors of enzymatic phospholipid hydrolysis.
Andreiuk
G M
GM
Kisel'
M A
MA
Litvinko
N M
NM
D000577:Amides / Q000494:pharmacology*; D002384:Catalysis; D005227:Fatty Acids / Q000494:pharmacology*; D008066:Lipolysis; D008823:Micelles; D017830:Octoxynol; D010713:Phosphatidylcholines / Q000378:metabolism*; D010741:Phospholipases A / Q000378:metabolism*; D054467:Phospholipases A2
D000577:Amides; D005227:Fatty Acids; D008823:Micelles; D010713:Phosphatidylcholines; D017830:Octoxynol; D010741:Phospholipases A; D054467:Phospholipases A2; C017251:1,2-oleoylphosphatidylcholine
Vliianie amidov zhirnykh kislot na kataliziruemyĭ fosfolipazoĭ A2 gidroliz fosfatidilkholina v mitsellakh.