[Strain-specific antibodies to wild poliomyelitis viruses as an index of the circulation of these viruses in a surveyed territory].
In response to vaccination or infection with wild poliovirus, some children can finely differentiate the virus structure and respond by forming strain-specific antibodies. The analysis of strain-specific antibodies indicates that in epidemically unfavorable regions strain-specific antibodies to wild poliovirus strains may prevail over those to vaccine poliovirus strains in children or occur with equal frequency. In epidemically favourable regions strain-specific antibodies to vaccine poliovirus strain significantly prevail in children or may be absent at all. The analysis of strain-specific antibodies makes it possible to retrospectively judge on the circulation of wild viruses in the surveyed region.
Seĭbil'
V B
VB
Chumakov Institute of Poliomyelitis and Viral Encephalitis, Moscow, Russia.
Malyshkina
L P
LP
Lavrova
I K
IK
Drozdov
S G
SG
D000914:Antibodies, Viral / Q000097:blood*; D000918:Antibody Specificity / Q000276:immunology*; D002648:Child; D003588:Cytopathogenic Effect, Viral; D004197:Disease Reservoirs; D006801:Humans; D009500:Neutralization Tests; D017955:Poliovirus / Q000276:immunology*; D011054:Poliovirus Vaccine, Inactivated / Q000276:immunology; D012189:Retrospective Studies; D013045:Species Specificity; D014610:Uzbekistan
D000914:Antibodies, Viral; D011054:Poliovirus Vaccine, Inactivated
Shtammospetsficheskie antitela k dikim virusam poliomielita kak pokazatel' tsirkuliatsii étikh virusov na obsleduemoĭ territorii.