title: [Primary amyloidosis AL as a cause of restrictive cardiomyopathy].
abstract: In a 71-year-old woman with macroglossia and heart failure, a monoclonal protein (kappa-light chains) was found in the serum. Congestive heart failure was diagnosed on the basis of heart catheterization and echocardiography. The tongue biopsy showed numerous amyloid fibrils, and plasmacytosis was present in the bone marrow. All these findings indicated a restrictive cardiomyopathy as part of a primary systemic amyloidosis.
authors.affiliation: Universitätspoliklinik für Ambulante Spezialmedizin Charité, Humboldt-Universität zu Berlin.
authors.forename: Y
authors.initials: Y
authors.lastname: Rückert
authors.forename: A
authors.initials: A
authors.lastname: Hansen
authors.forename: W V
authors.initials: WV
authors.lastname: Dörffel
authors.forename: B
authors.initials: B
authors.lastname: Eckert
authors.forename: J
authors.initials: J
authors.lastname: Scholze
mesh_terms: D000368:Aged; D000682:Amyloid / Q000097:blood*; D000686:Amyloidosis / Q000175:diagnosis* / Q000473:pathology; D001706:Biopsy; D002313:Cardiomyopathy, Restrictive / Q000175:diagnosis* / Q000473:pathology; D004452:Echocardiography; D005260:Female; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000097:blood; D007145:Immunoglobulin kappa-Chains / Q000097:blood; D009206:Myocardium / Q000473:pathology; D013363:Submandibular Gland / Q000473:pathology; D014059:Tongue / Q000473:pathology
chemical_list: D000682:Amyloid; D007147:Immunoglobulin Light Chains; D007145:Immunoglobulin kappa-Chains; C035222:amyloid protein AL
vernacular_title: Primäre Amyloidose AL als Ursache der restriktiven Kardiomyopathie.