title: Open access gastroscopy findings are unrelated to the use of aspirin and non-steroidal anti-inflammatory drugs.
abstract: This study aims to determine whether priority should be given to patients taking non-steroidal anti-inflammatory drugs (NSAIDs) or aspirin when selecting which dyspeptic patients to refer for open access gastroscopy. A total of 8156 patients underwent gastroscopy, all of whom had upper gastrointestinal symptoms. Patients taking NSAIDs or aspirin showed no significant differences in the frequency of ulcer disease when age-matched groups were compared. Although NSAIDs and aspirin are frequently implicated in gastrointestinal bleeding in the elderly, patients referred for investigation of dyspepsia show no increase in major endoscopic pathology.
authors.affiliation: Endoscopy Centre, South Cleveland Hospital, Middlesbrough.
authors.forename: J C
authors.initials: JC
authors.lastname: Mansfield
authors.forename: J R
authors.initials: JR
authors.lastname: Greenaway
authors.forename: B R
authors.initials: BR
authors.lastname: Contractor
authors.forename: N
authors.initials: N
authors.lastname: Idle
authors.forename: M G
authors.initials: MG
authors.lastname: Bramble
mesh_terms: D000328:Adult; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D001241:Aspirin / Q000009:adverse effects*; D004415:Dyspepsia / Q000209:etiology; D004941:Esophagitis / Q000139:chemically induced*; D005773:Gastroscopy; D006801:Humans; D008875:Middle Aged; D018579:Patient Selection; D010437:Peptic Ulcer / Q000139:chemically induced*; D012189:Retrospective Studies
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D001241:Aspirin