title: [The risk of palliative operation for bone metastasis].
abstract: Palliative operations for various bone metastases are being performed more frequently than before with the improvement of surgical technique and the development of new instruments. However, anesthesia in advanced cancer patients who are under palliative care accompanies inherent risks which are uncommon in general orthopaedic populations. Thus, we made a retrospective analysis of the medical records of 59 patients scheduled for palliative operation against metastatic bone lesions during the last 4 years. The survey revealed 5 cases of perioperative lethal events. Two of them died preoperatively from the hepatic failure and unexpected cerebral tumor embolism. An intraoperative cardiac arrest secondary to pulmonary embolism occurred in a patient during intramedullary nailing. There was a patient who developed disseminated intravascular coagulation and acute renal failure after posterior fixation of the lumbar vertebrae. The remaining one patient with superior vena cava syndrome developed life-threatening airway obstruction during general anesthesia with endotracheal intubation. We conclude that the exact evaluation of the patient's condition and the careful management of vital organ functions are mandatory during the perioperative period. In this regard, the anesthesiologists should be involved not only in the intraoperative anesthetic management but also in the perioperative care of the patients with bone metastasis.
authors.affiliation: Department of Anesthesia, National Cancer Center Hospital East, Kashiwa.
authors.forename: T
authors.initials: T
authors.lastname: Tsukeoka
authors.forename: T
authors.initials: T
authors.lastname: Kochi
authors.forename: K
authors.initials: K
authors.lastname: Koide
authors.forename: M
authors.initials: M
authors.lastname: Tahara
authors.forename: T
authors.initials: T
authors.lastname: Koyama
authors.forename: M
authors.initials: M
authors.lastname: Kitou
authors.forename: T
authors.initials: T
authors.lastname: Umeda
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000556:secondary* / Q000601:surgery*; D001943:Breast Neoplasms / Q000473:pathology; D005260:Female; D005598:Fractures, Spontaneous / Q000601:surgery; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures; D010166:Palliative Care; D012189:Retrospective Studies; D012306:Risk