title: Translocation (X;1) reveals metastasis 31 years after renal cell carcinoma.
abstract: Cytogenetic investigation of a metastatic lesion appearing 31 years after nephrectomy allowed for the diagnosis of a renal cell carcinoma. The der(X)t(X;1)(p11.2;q21.1) found in this case and review of the 14 other cases previously reported indicates that this chromosome lesion may characterize a specific subgroup of renal cell carcinoma, with distinct histology and age distribution that also can occur in females.
authors.affiliation: Center for Human Genetics, Leuven, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Dal Cin
authors.forename: M
authors.initials: M
authors.lastname: Stas
authors.forename: R
authors.initials: R
authors.lastname: Sciot
authors.forename: I
authors.initials: I
authors.lastname: De Wever
authors.forename: B
authors.initials: B
authors.lastname: Van Damme
authors.forename: H
authors.initials: H
authors.lastname: Van den Berghe
mesh_terms: D002292:Carcinoma, Renal Cell / Q000235:genetics* / Q000473:pathology*; D002878:Chromosomes, Human, Pair 1; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000235:genetics* / Q000473:pathology*; D008875:Middle Aged; D014178:Translocation, Genetic; D014960:X Chromosome