title: [Effectiveness of immunodiagnosis of drug intolerance in adolescents having tuberculosis and concomitant diseases].
abstract: Fifty seven adolescents having tuberculosis and clinical signs of drug intolerance were examined by immunological tests (thermistometry and blast-transformation reaction in 20 and 37 patients, respectively). Of them 30 patients had concomitant diseases. Patients with concurrent abnormalities require laboratory evidence for drug intolerance. Of all negative tests, they were more common in patients with concomitant abnormalities (65.5%), but they amounted to 34.5% in those without concomitant abnormalities. There was a similarity of the clinical symptomatology of intolerance with negative immunological responses to the exacerbation or increased symptoms of concomitant diseases.
authors.affiliation: Central NII of Tuberculosis RAMN, Moscow.
authors.forename: L I
authors.initials: LI
authors.lastname: Rusakova
authors.forename: V I
authors.initials: VI
authors.lastname: Gergert
authors.forename: Z P
authors.initials: ZP
authors.lastname: Abramova
authors.forename: E S
authors.initials: ES
authors.lastname: Ovsiankina
mesh_terms: D000293:Adolescent; D000995:Antitubercular Agents / Q000009:adverse effects*; D048909:Diabetes Complications; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000209:etiology; D005128:Eye Diseases / Q000150:complications; D005767:Gastrointestinal Diseases / Q000150:complications; D005921:Glomerulonephritis / Q000150:complications; D006801:Humans; D007159:Immunologic Tests; D012680:Sensitivity and Specificity; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents
vernacular_title: Effektivnost' immunodiagnostiki lekarstvennoí neperenosimosti u podrostkov, bol'nykh tuberkulezom i imeiushchikh soputstvuiushchie zabolevaniia.