[Comparison of thrombocyte concentrates from buffy coats after 3 and 16 hours of storage].
Since extended storage of the buffy coat (BC) might be disadvantageous for the platelet function because of granulocyte proteases we investigated platelet concentrates (PC) prepared from BC which rested either for 3 h (n = 18) or 16 h (n = 41) before further preparation. We found significant differences especially in the morphology score, pH and lactate in favour of the PC from 3-hour-BC. The differences decreased during the 5-day storage. PC of unacceptable quality (n = 4) only derived from 16-hour-BC. Therefore, the use of PC from BC stored for more than 4 h at least requires an adequate quality control before delivery.
Häberle
H
H
Abteilung für Transfusionsmedizin und Gerinnungsphysiologie, Universität Marburg, Deutschland.
Schulzki
T
T
Kretschmer
V
V
D001792:Blood Platelets; D001793:Blood Preservation; D010450:Endopeptidases / Q000097:blood; D006098:Granulocytes / Q000201:enzymology; D006801:Humans; D007962:Leukocytes; D010983:Plateletpheresis / Q000379:methods*; D013997:Time Factors
D010450:Endopeptidases
Vergleich zwischen Thrombozytenkonzentraten aus Buffy coat mit 3 und 16 Stunden Lagerungszeit.