Preliminary results with technetium-99m MIBI SPECT imaging in patients with brain tumors: correlation with histological and neuroradiological diagnoses and therapeutic response.
SPECT using Tc-99m MIBI was performed in patients with brain tumors in order to determine Tc-99m MIBI uptake in brain tumors and to evaluate the efficacy of MIBI imaging in the assessment of treatment response. A MIBI uptake index was calculated on SPECT imaging. All tumors with a MIBI-index higher than 7.5 were malignant. In the tumors evaluated before and after radiochemotherapy, the MIBI-index immediately following therapy correlated with treatment response 2 months after therapy. Thus, semiquantitative assessment using Tc-99m MIBI SPECT imaging may be useful in the evaluation of treatment response.
Tomura
N
N
Department of Radiology, Akita University School of Medicine, Japan.
Hirano
H
H
Watanabe
O
O
Kato
K
K
Sasaki
K
K
Watarai
J
J
Sasajima
H
H
Ito
Y
Y
Mineura
K
K
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015901:Angiography, Digital Subtraction; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon
D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi