title: [Intraoperative malignant hyperthermia: apropos of a case].
abstract: Malignant hyperthermia (MHS) is a rare potentially fatal complication of general anesthesia. Anesthetic agents most frequently incriminated are succinylcholine and halogenated agents. Respiratory acidosis is the most specific and sensitive sign. Hyperthermia per se may occur secondarily or may stay totally absent. Tachycardia and/or arrhythmias often develop due to hyperkalemia and metabolic acidosis. Muscle rigidity whenever present is pathognomonic The "gold standard" test for the diagnosis of MHS is the halothane-caffeine contracture test. Dantrolene is the treatment of choice and prognosis depends on the early administration of this agent.
authors.affiliation: Service d'Anesthésie-Réanimation, Hôtel-Dieu de France, Beyrouth, Liban.
authors.forename: S
authors.initials: S
authors.lastname: Madi-Jebara
authors.forename: P
authors.initials: P
authors.lastname: Yazbeck
authors.forename: M
authors.initials: M
authors.lastname: Bou-Khalil
authors.forename: A
authors.initials: A
authors.lastname: Cherfane
authors.forename: M C
authors.initials: MC
authors.lastname: Antakly
mesh_terms: D003620:Dantrolene / Q000627:therapeutic use; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008305:Malignant Hyperthermia / Q000175:diagnosis / Q000628:therapy; D008875:Middle Aged; D009125:Muscle Relaxants, Central / Q000627:therapeutic use
chemical_list: D009125:Muscle Relaxants, Central; D003620:Dantrolene
vernacular_title: Hyperthermie maligne per opératoire: à propos d'un cas.