title: [Seroepidemiological considerations of the incidence of viral hepatitis C in some population groups].
abstract: In the interval 1985-1994, in the Iaşi district, the reported cases of viral hepatitis (VH) have recorded annual morbidity rates ranging between 67/100,000 inhabitants in 1993 and 373/100,000 in 1990. VH attributed to HAV and HBV has represented, with yearly differences, 62% to 94% of all cases. Posttransfusion viral hepatitis (PTVH) has determined a morbidity of 0.51/100,000 inhabitants in 1986 and 8.34/100,000 in 1994. PTVH without AgHBs ranged from 16.3% in 1993 to 94.0% in 1987, as compared to 6.0% in 1987 and 1988 and 75.0% in 1985 for PTVH with AgHBs. In the interval under study 70.9% of the PTVH cases were most likely determined by HCV and 28.9% by HBV (AgHBs+). From all PTVH cases, 64.0% were from urban areas, 59.3% were females, 92.5% belonged to over 20 years age groups, and 31.3% were industrial workers, the remainder belonging to other 5 occupational groups. In 241 patients (18.2%) admitted for liver disorders, posttransfusion hepatitis included, AcHCV was present in 39.4%, of which 45.2% belonged to the age groups 20-60 years. The results of some investigations carried out on 4471 blood donors (72.4% males, 85.4% aged between 21 ad 50 years, 86.4% from urban areas, 62.1% workers in industry and building) are presented. Out of these, 217 (4.9%) presented to hepatitis C virus (AcHCV). Occupational distribution of AcHCV possessors shows that 44.2% are workers in the heavy industry, 14.8% in the light industry and 12.9% unemployed. Sera were tested by Monolisa New Antigens, and those with AcHCV were reassessed with Monolisa, Murex anti HCV, ORTO-HCV 3.0 and confirmed by Immunoblot DECISCAN, with 5 antigens.
authors.affiliation: Universitatea de Medicină şi Farmacie Gr. T. Popa, Iaşi.
authors.forename: A
authors.initials: A
authors.lastname: Ivan
authors.forename: D
authors.initials: D
authors.lastname: Azoicăi
authors.forename: R
authors.initials: R
authors.lastname: Grigorescu
authors.forename: G
authors.initials: G
authors.lastname: Pisică
authors.forename: M
authors.initials: M
authors.lastname: Groll
authors.forename: M
authors.initials: M
authors.lastname: Trifan
authors.forename: M
authors.initials: M
authors.lastname: Bârhală
authors.forename: I
authors.initials: I
authors.lastname: Mitroi
authors.forename: L
authors.initials: L
authors.lastname: Chiriac
authors.forename: D
authors.initials: D
authors.lastname: Scripcaru
mesh_terms: D000328:Adult; D017677:Age Distribution; D001782:Blood Donors / Q000706:statistics & numerical data; D005260:Female; D006514:Hepatitis B Surface Antigens / Q000097:blood; D006526:Hepatitis C / Q000453:epidemiology* / Q000276:immunology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009017:Morbidity / Q000639:trends; D012383:Romania / Q000453:epidemiology; D016036:Seroepidemiologic Studies; D017678:Sex Distribution; D012959:Socioeconomic Factors
chemical_list: D006514:Hepatitis B Surface Antigens
vernacular_title: Consideraţii sero-epidemiologice privind incidenţa hepatitei virale C în unele grupuri populaţionale.