Anti-epiligrin (laminin 5) cicatricial pemphigoid.
Cicatricial pemphigoid is an autoimmune disease predominantly of elderly patients. Recently, a subtype of cicatricial pemphigoid with antibodies to epiligrin (laminin 5) was described. We report a patient in whom anti-epiligrin cicatricial pemphigoid was identified. He presented with cutaneous, oral and ocular involvement. He has shown initial improvement on corticosteroids and cyclophosphamide.
Allbritton
J I
JI
Department of Dermatology, Johns Hopkins Hospital, Baltimore, MD 21287, USA.
Nousari
H C
HC
Anhalt
G J
GJ
D001323:Autoantibodies / Q000032:analysis*; D001327:Autoimmune Diseases / Q000276:immunology* / Q000473:pathology; D015815:Cell Adhesion Molecules / Q000276:immunology*; D003229:Conjunctival Diseases / Q000276:immunology / Q000473:pathology; D005455:Fluorescent Antibody Technique; D006801:Humans; D008297:Male; D008875:Middle Aged; D010390:Pemphigoid, Benign Mucous Membrane / Q000276:immunology* / Q000473:pathology; D015531:Radioimmunoprecipitation Assay; D000097794:Kalinin
D001323:Autoantibodies; D015815:Cell Adhesion Molecules; D000097794:Kalinin