[The activating effect of antisarcolemmal antibodies on the contractile reactions of the papillary muscles of the rat heart].
In experiments on the hyperpermeable papillary muscles (PM), we studied the antimembranous antibodies effects on their contractile responses. It has been found that antibodies enhance the amplitude of isometric contraction. Specific antibodies were suggested to induce the release of Ca2+ from the sarcoplasmatic reticulum in the PM of rats.
Ianchiĭ
R I
RI
D000818:Animals; D000906:Antibodies / Q000302:isolation & purification / Q000494:pharmacology*; D000918:Antibody Specificity; D007537:Isometric Contraction / Q000187:drug effects*; D008297:Male; D010210:Papillary Muscles / Q000187:drug effects*; D051381:Rats; D017208:Rats, Wistar; D012508:Sarcolemma / Q000276:immunology*; D012996:Solutions
D000906:Antibodies; D012996:Solutions
Aktyvuiuchyĭ efekt antysarkolemal'nykh antytil na skorotlyvi reaktsiï papiliarnykh m'iaziv sertsia shchura.