Candida albicans suppresses transcription of melanogenesis enzymes in cultured melanocytes.
Human skin can be colonized by different yeasts that may have an impact on skin pigmentation. In order to study this effect normal human melanocytes were cultured with different yeasts. Reverse transcription polymerase chain reaction (RT-PCR) analysis gives evidence that Candida albicans suppresses the transcription of melanogenesis enzymes.
Kippenberger
S
S
Abteilung 1, Klinikum der Johann Wolfgang Goethe-Universität, Frankfurt/Main, Germany.
Bernd
A
A
Menzel
I
I
Loitsch
S
S
Ramirez-Bosca
A
A
Kaufmann
R
R
D019747:Aldose-Ketose Isomerases; D002176:Candida albicans / Q000502:physiology*; D002478:Cells, Cultured; D005656:Fungal Proteins / Q000235:genetics; D006801:Humans; D008544:Melanocytes / Q000201:enzymology* / Q000382:microbiology*; D014442:Monophenol Monooxygenase / Q000235:genetics; D016133:Polymerase Chain Reaction; D012880:Skin Pigmentation / Q000235:genetics*; D014158:Transcription, Genetic
D005656:Fungal Proteins; D014442:Monophenol Monooxygenase; D019747:Aldose-Ketose Isomerases