title: The effectiveness of intrauterine insemination in couples with sterility due to male infertility with and without a woman's hormone factor.
abstract: OBJECTIVE
  To examine the efficacy of IUI on fecundity and baby-take-home rates in cases of infertility attributable to a male factor with and without a woman's hormone factor.
  
  
  METHODS
  Retrospective analysis.
  
  
  METHODS
  Department of Gynecology and Obstetrics at the General Public Hospital, Horn, Austria.
  
  
  METHODS
  Seventy-eight long-standing involuntarily childless couples.
  
  
  METHODS
  After a follicular phase GnRH analog (buserelin) protocol with hMG stimulation of the woman and a Percoll gradient preparation and capacitation of the man's semen, an IUI was performed.
  
  
  METHODS
  Fecundity and baby-take-home rates.
  
  
  RESULTS
  One hundred nine inseminations were followed by 53 pregnancies (48.6%; 95% confidence intervals (CI) 38.9%-58.4%) and 38 deliveries (34.9%; 95% CI 26.0%-44.6%). Forty-nine children were born and 47 are alive (43.1%).
  
  
  CONCLUSIONS
  Intrauterine insemination combined with buserelin gonadotropin stimulation, Percoll semen preparation, and sperm capacitation is a feasible solution to the problem of sterility attributable to a male factor with and without a woman's hormone factor.
authors.affiliation: Department of Gynecology and Obstetrics, General Public Hospital, Horn, Austria.
authors.forename: E
authors.initials: E
authors.lastname: Rammer
authors.forename: F
authors.initials: F
authors.lastname: Friedrich
mesh_terms: D000293:Adolescent; D000328:Adult; D001723:Birth Rate; D002064:Buserelin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D007248:Infertility, Male / Q000628:therapy*; D007317:Insemination, Artificial, Homologous; D008297:Male; D008596:Menotropins / Q000627:therapeutic use; D008875:Middle Aged; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D012189:Retrospective Studies; D013075:Sperm Capacitation / Q000502:physiology
chemical_list: D008596:Menotropins; D002064:Buserelin