title: Pesticides poisonings in clinical and medicolegal aspect.
abstract: In the course of time, progress in knowledge, after many years of a widespread use of pesticides, it is necessary to evaluate negative results they cause. Poisonings with these xenobiotics have claimed new tasks and problems for toxicology. The present study comprises some complex problems of pesticides poisonings on the basis of examinations referring to non-fatal and fatal cases of poisonings in clinical and medicolegal aspects. They include cholinesterase inhibitor poisonings, dipyridil herbicides and chlorphenoxyacetate as well. On the basis of quantitative determinations of cholinesterase inhibitors relations between blood concentration and toxic effects were considered. Moreover, an elimination of inhibitors from blood in relation to the method of treatment and kind of pesticide was observed. In fatal cases of intoxication morphological changes in tissues, pesticides distribution and antemortem-postmortem relations were discussed. Toxicological findings in the cases examined constitute a data library for complex clinical and medicolegal purposes.
authors.affiliation: Department of Forensic Medicine, Collegium Medicum, Jagiellonian University, Kraków.
authors.forename: M
authors.initials: M
authors.lastname: Kłys
authors.forename: J
authors.initials: J
authors.lastname: Pach
authors.forename: B
authors.initials: B
authors.lastname: Groszek
mesh_terms: D006801:Humans; D010575:Pesticides / Q000506:poisoning*; D011041:Poisoning / Q000175:diagnosis* / Q000378:metabolism / Q000628:therapy; D015262:Xenobiotics / Q000506:poisoning
chemical_list: D010575:Pesticides; D015262:Xenobiotics