title: Uvulopalatopharyngoplasty for the obstructive sleep apnoea syndrome: value of polysomnography, Mueller manoeuvre and cephalometry in predicting surgical outcome.
abstract: Sixty consecutive patients with the obstructive sleep apnoea syndrome (53 men and seven women) were analysed by questionnaire, polysomnography, röntgenographic cephalometry and the Mueller manoeuvre before and 6 months after uvulopalatopharyngoplasty (UPPP), to assess the surgical outcome and the prognostic value of preoperative evaluation. Seventy-three per cent of patients reported improvement of snoring and 55% reported improvement of excessive daytime sleepiness. Thirty-five per cent showed a decrease of at least 50% in the desaturation index, and 13% had a postoperative desaturation index below 5. Although the improvement of desaturation parameters was marked in some patients, the overall change was not significant. Neither the Body Mass Index (BMI), nor any of the cephalometric variables were significantly correlated to surgical outcome. Increased difference in collapsibility between the soft palate and the base of the tongue showed a close to significant relation with the improvement of desaturation index. High desaturation index, low mean saturation and deep lowest saturation were found to be slightly predictive of improvement in nocturnal desaturation. In a multivariate analysis however no significant predictors could be identified. It is concluded that UPPP is effective in reducing snoring and daytime sleepiness over a 6-month follow-up period, but that the overall improvement in nocturnal desaturation is limited and difficult to predict. Further research is needed to evaluate the long-term efficacy of UPPP.
authors.affiliation: Department of Neurology, University Hospital Rotterdam, The Netherlands.
authors.forename: H
authors.initials: H
authors.lastname: Boot
authors.forename: R M
authors.initials: RM
authors.lastname: Poublon
authors.forename: R
authors.initials: R
authors.lastname: Van Wegen
authors.forename: J M
authors.initials: JM
authors.lastname: Bogaard
authors.forename: P I
authors.initials: PI
authors.lastname: Schmitz
authors.forename: A Z
authors.initials: AZ
authors.lastname: Ginaï
authors.forename: F G
authors.initials: FG
authors.lastname: Van der Meché
mesh_terms: D015992:Body Mass Index; D002508:Cephalometry; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010160:Palate, Soft / Q000601:surgery*; D010614:Pharynx / Q000601:surgery*; D017286:Polysomnography; D011237:Predictive Value of Tests; D011300:Preoperative Care; D012891:Sleep Apnea Syndromes / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D014609:Uvula / Q000601:surgery*