Successful treatment of recurrent uterine bleeding during tamoxifen therapy by endometrial ablation.
Recurrent bleeding occurred in a premenopausal breast cancer woman during tamoxifen therapy. This bleeding required three curettages. Atypical hyperplasia and carcinoma were excluded, and the patient was prepared for endometrial ablation with two GnRH agonist injections. An endometrial ablation using the roller ball technique was carried out without complications. Tamoxifen therapy was continued postoperatively. During 24 months' follow-up the patient experienced no bleeding and no endometrium was seen by sonography.
Römer
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Department of Obstetrics and Gynecology, Ernst-Moritz-Arndt-University of Greifswald, Germany.
D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects* / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy; D017115:Catheter Ablation / Q000379:methods*; D004714:Endometrial Hyperplasia / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D012008:Recurrence; D013629:Tamoxifen / Q000009:adverse effects* / Q000627:therapeutic use; D014463:Ultrasonography; D014592:Uterine Hemorrhage / Q000139:chemically induced* / Q000503:physiopathology / Q000628:therapy*
D018931:Antineoplastic Agents, Hormonal; D013629:Tamoxifen