title: [Clinical evaluation for radiotherapy of metastatic brain tumors in lung cancer: prognostic analyses relevant to QOL].
abstract: From 1986 through 1992, 144 patients with metastatic brain tumors of lung cancer were treated with X-ray irradiation to whole brain or a comparatively wide field of the brain. To identify the subset of patients indicated for boost therapy like a stereotactic radiotherapy, we have analyzed the treatment results concerning both survival and performance status (PS). Median survival time of the patients in good PS (0-2) was 6.7 months, which was significantly better than 2.3 months in poor PS (3-4). Complete tumor-resectability, age, steroid therapy and condition within two months after the beginning of brain irradiation, seemed to be important prognostic indicators correlated with PS by both univariate and multivariates analyses.
authors.affiliation: Dept. of Radiology, National Sapporo Hospital, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Myojin
authors.forename: M
authors.initials: M
authors.lastname: Nishio
authors.forename: F
authors.initials: F
authors.lastname: Mizoguchi
authors.forename: K
authors.initials: K
authors.lastname: Kawashima
authors.forename: N
authors.initials: N
authors.lastname: Mita
authors.forename: A
authors.initials: A
authors.lastname: Fujita
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000401:mortality / Q000532:radiotherapy* / Q000556:secondary*; D016371:Cranial Irradiation; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D011379:Prognosis; D016016:Proportional Hazards Models; D011788:Quality of Life; D011879:Radiotherapy Dosage; D015996:Survival Rate