The impact of current use of hormone replacement therapy on prognostic factors and surgical treatment of new breast cancers.
When postmenopausal women were diagnosed with breast cancer while taking hormone replacement, no adverse effects were noted in either clinical or prognostic factors when compared to a similar group not on hormones. Younger age at diagnosis and an increased chance of carcinoma in situ were noted in those on hormones. A surveillance or observational bias is one explanation for these findings. A promotional effect of hormone replacement therapy could not be eliminated based on this study.
Stolier
A J
AJ
The Breast Center, New Orleans, LA 70115, USA.
Mera
R
R
Schapira
D
D
D000367:Age Factors; D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010052:Ovariectomy; D017698:Postmenopause; D011379:Prognosis; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis
D011960:Receptors, Estrogen; D011980:Receptors, Progesterone