title: Local Research Ethics Committees can audit ethical standards in research.
abstract: OBJECTIVE
  To show that a Local Research Ethics Committee (LREC) can carry out an audit of ethical standards in research. To find out if a researcher met certain ethical standards in recruiting subjects for clinical trials and in obtaining their consent.
  
  
  METHODS
  Postal questionnaire.
  
  
  METHODS
  Clinical research by one doctor during one year.
  
  
  METHODS
  Eleven patients entered in clinical trials.
  
  
  METHODS
  Success in ethics committee obtaining data. Achievement of ethical standards in recruitment of subjects and in obtaining consent.
  
  
  RESULTS
  The audit was successfully carried out and standards were partly met.
  
  
  CONCLUSIONS
  Local Research Ethics Committees can carry out audits of the conduct of research projects which they have approved. Provision for possible audits can be made at the time of application to the committee. Our committee thought the ethical standards in the research which we audited were acceptable.
authors.affiliation: Princess Royal Hospital, Haywards Heath, West Sussex.
authors.forename: J
authors.initials: J
authors.lastname: Berry
mesh_terms: D032882:Comprehension; D030881:Disclosure; D026724:Ethical Review; D028744:Ethics Committees, Research; D004992:Ethics, Medical; D006801:Humans; D007258:Informed Consent; D008485:Medical Audit; D012106:Research / Q000592:standards*; D035842:Research Subjects; D011795:Surveys and Questionnaires; D036302:Therapeutic Human Experimentation; D006113:United Kingdom