title: Cervical amyloidoma of C2. Case report and review of the literature.
abstract: METHODS
  Second published report of a patient with amyloidoma of the upper cervical spine.
  
  
  OBJECTIVE
  To describe a patient with rare radiculopathy to alert other physicians to consider amyloid tumor as a differential diagnosis of locally destructive spine lesions.
  
  
  BACKGROUND
  Localized amyloid tumor of the bone is a rare disease. Only seven cases of spine involvement have been reported. Appropriate tissue sampling is required to establish the diagnosis. Histopathologic examination shows pathognomonic apple-green birefringence under polarized light. When bone is involved with amyloid, it is most commonly associated with multiple myeloma or other plasma cell-dyscrasias.
  
  
  METHODS
  This case was described, and pertinent literature was reviewed.
  
  
  RESULTS
  The patient showed persistent neurologic improvement after transoral complete tumor removal, followed by a secondary posterior stabilization procedure using transarticular C1-C2 screws.
  
  
  CONCLUSIONS
  Amyloidomas are benign lesions with no associated documented risk for the development of plasmocytoma-related diseases. The clinical and radiographic manifestations of this lesion are nonspecific. A cure is possible with complete resection of the tumor and no adjuvant management procedures.
authors.affiliation: Division of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona, USA.
authors.forename: F
authors.initials: F
authors.lastname: Porchet
authors.forename: V K
authors.initials: VK
authors.lastname: Sonntag
authors.forename: N
authors.initials: N
authors.lastname: Vrodos
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D001863:Bone Screws; D002574:Cervical Vertebrae / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D013120:Spinal Cord Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D013123:Spinal Fusion; D014057:Tomography, X-Ray Computed