[Sudden cardiac death in patients with arterial hypertension and left ventricular hypertrophy on antihypertensive therapy].
The hypertrophy of the left ventricle in patients with arterial hypertension is an independent risk factor which increases c 9 times the probability of sudden cardiac death. Despite the fact that the incidence of sudden cardiac death in patients with arterial hypertension is low, regarding the high occurrence of hypertension it represents a significant medical problem. The therapy of arterial hypertension is able to decrease the general and cardiovascular mortalities with significant interspecies characteristics of individual antihypertensive drugs, as well as to promote the regression of hypertrophy of the left ventricle. The therapy per se can however increase the risk of cardiovascular complications: until now the complication of the therapy by diuretics rich in potassium and beta-blockers are best distinguished. Calcium antagonists are effective antihypertensive drugs but they do not decrease the total mortality. ACE inhibitors have a marked antihypertensive effect and few adverse effects, but until now there is not a sufficient number of large prospective studies which would definitely confirm the preliminary promising findings. Despite the presented problems the cured patients with arterial hypertension have a substantially better prognosis than patients that are not being cured.
Lietava
J
J
II. interná klinika Fakultnej nemocnice a Lekárskej fakulty Univerzity Komenského v Bratislave, Slovakia.
Dúbrava
M
M
D000959:Antihypertensive Agents / Q000627:therapeutic use*; D016757:Death, Sudden, Cardiac / Q000209:etiology*; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000188:drug therapy; D017379:Hypertrophy, Left Ventricular / Q000150:complications*; D011379:Prognosis; D012307:Risk Factors
D000959:Antihypertensive Agents
Náhla srdcová smrt u chorých s artériovou hypertenziou, hypertrofiou l'avej komory a pri liecbe antihypertenzívami.