title: Ion exchanger modified PVC membranes--selectivity studies and response amplification of oxalate and lactate enzyme electrodes.
abstract: We report on a novel method of oxidase enzyme electrode response amplification, using unplasticized PVC and plasticized PVC, respectively. The anion exchanger tricaprylylmethylammonium chloride (Aliquat 336s) and hydrophobic isopropylmyristate (IPM) plasticizer have been used together to modify PVC. Resulting structures are anionic substrate selective and hydrogen peroxide impermeable and can be used as outer membranes of a classical dual membrane amperometric enzyme electrode where an oxidase is used to generate H2O2 for electrochemical detection. Their effect on sensor sensitivity and linearity is considered.
authors.affiliation: University of Wales (Bangor), Institute of Molecular and Biomolecular Electronics, UK.
authors.forename: S M
authors.initials: SM
authors.lastname: Reddy
authors.forename: P M
authors.initials: PM
authors.lastname: Vadgama
mesh_terms: D015374:Biosensing Techniques; D004058:Diffusion; D007474:Ion Exchange; D019344:Lactic Acid / Q000032:analysis*; D016014:Linear Models; D008567:Membranes, Artificial; D010070:Oxalates / Q000032:analysis*; D011143:Polyvinyl Chloride; D000644:Quaternary Ammonium Compounds; D012680:Sensitivity and Specificity
chemical_list: D008567:Membranes, Artificial; D010070:Oxalates; D000644:Quaternary Ammonium Compounds; D019344:Lactic Acid; C037759:trioctylmethylammonium; D011143:Polyvinyl Chloride