title: Evaluation of the Brusini glaucoma staging system for follow-up in glaucoma.
abstract: BACKGROUND
  Brusini developed a new interpretation system for Octopus and Humphrey automated perimeters that is based on mean defect (MD) and corrected loss variance (CLV) or corrected pattern standard deviation (CPSD). This study tested the performance of Brusini's glaucoma staging system (GSS) in staging and follow-up.
  
  
  METHODS
  Retrospectively, 610 visual fields of 64 eyes of open-angle glaucoma patients were analyzed with Brusini GSS and compared with Aulhorn-Karmeyer stages and by PeriData 7.0 trend analysis.
  
  
  RESULTS
  Follow-up was comparable to PeriData 7.0 trend analysis in 97%. Change was observed in 41% of eyes, i.e., initial improvement (19% eyes), deterioration (16%), and after an initial improvement, either deterioration (11%) or a stable period (5%). No change was seen in 59% of the eyes, of which 30% showed small and 19% high long-term fluctuation (LF) due to fatigue effect, poor cooperation of patient, impaired reliability, or short-term fluctuation (SF) greater than 1.7 dB. However, for 8% of the eyes there was no apparent reason for high LF.
  
  
  CONCLUSIONS
  Brusini GSS is useful for staging and recommended for follow-up evaluation of visual fields in glaucoma.
authors.affiliation: University Eye clinic, Basel, Switzerland.
authors.forename: I
authors.initials: I
authors.lastname: Koçak
authors.forename: M
authors.initials: M
authors.lastname: Zulauf
authors.forename: P
authors.initials: P
authors.lastname: Hendrickson
authors.forename: D
authors.initials: D
authors.lastname: Stümpfig
mesh_terms: D000368:Aged; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000145:classification* / Q000503:physiopathology; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D058609:Visual Field Tests / Q000379:methods* / Q000706:statistics & numerical data; D014794:Visual Fields / Q000502:physiology*