title: The Addiction Severity Index in clinical efficacy trials of medications for cocaine dependence.
abstract: In sum, the ASI provides a standard and multidimensional initial evaluation of the subject. Furthermore, a profile of subjects is obtained that can be compared at different evaluation points, providing secondary outcomes. However, for the purposes of clinical trials evaluating pharmacotherapy for cocaine abusers, supplemental measures are needed at both baseline and followup to more specifically address cocaine use and problems.
authors.affiliation: Center for Studies of Addiction, University of Pennsylvania School of Medicine/Philadelphia VA Medical Center 19104-6178, USA.
authors.forename: J S
authors.initials: JS
authors.lastname: Cacciola
authors.forename: A I
authors.initials: AI
authors.lastname: Alterman
authors.forename: C P
authors.initials: CP
authors.lastname: O'Brien
authors.forename: A T
authors.initials: AT
authors.lastname: McLellan
mesh_terms: D003042:Cocaine; D006801:Humans; D009294:Narcotics; D011569:Psychiatric Status Rating Scales; D019966:Substance-Related Disorders / Q000188:drug therapy* / Q000523:psychology*
chemical_list: D009294:Narcotics; D003042:Cocaine