[Ionol phosphorus organic analogs and stabilization of levorin].
Stability of levorin isolated and purified with the use of ionole phosphorus organic analogs having in their structure phosphate, phosphonate and phosphonite groups was studied. The compound having in its structure (in addition to tertiary butyl substitutes) the phosphonite group with the P-H bond increasing the compound antioxidant property was shown to have the highest stabilizing effect. The results of the study made it possible to recommend the use of the space complicated phenols with the structure fragments of the P-H bond type as antioxidants in production of levorin.
Belakhov
V V
VV
Research Technological Institute of Antibiotics and Medical Enzymes, St. Petersburg.
Shenin
Iu D
IuD
Nifant'ev 'EE
Kukhareva
T S
TS
Soldatova
I A
IA
D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry; D002084:Butylated Hydroxytoluene / Q000031:analogs & derivatives*; D002174:Candicidin / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D002175:Candida / Q000187:drug effects; D004355:Drug Stability; D008826:Microbial Sensitivity Tests; D010758:Phosphorus / Q000737:chemistry; D013329:Structure-Activity Relationship
D000935:Antifungal Agents; D000975:Antioxidants; D002174:Candicidin; D002084:Butylated Hydroxytoluene; D010758:Phosphorus
Ispol'zovaniephosphoroorganicheskikh analogov ionola dlia stabilizatsii levorina.