[Cardiovascular effects of AV interval shortening with electrical stimulation in dilated cardiomyopathy].
BACKGROUND
A temporal alteration between atrial and ventricular contraction, in which the last one would be abnormally retarded, could exist in patients with dilated cardiomyopathy. This alteration could have adverse hemodynamic effects.


OBJECTIVE
To study the hemodynamic modifications caused by an artificial shortening of AV interval in patients with dilated cardiomyopathy.


METHODS
Nine patients with dilated cardiomyopathy were studied. Hemodynamic and tissular perfusion values, echocardiographic and radioisotopic ventricular function parameters were measured before and after six hours of AV interval shortening with electrical stimulation of the heart.


RESULTS
After electrical stimulation, cardiac output increased from 3.38 +/- 0.8 to 3.87 +/- 0.79 l/min (p< 0.05). Pulmonary capillary pressure decreased from 23.8 +/- 8.9 to 19.8 +/- 9.2 mm Hg (p = NS). There were no significant changes in ventricular function parameters or in systemic and pulmonary pressures.


CONCLUSIONS
Electrical shortening of AV interval in patients with dilated cardiomyopathy increases cardiac output but does not change ventricular function parameters.
Fajuri
A
A
Departamento de Enfermedades Cardiovasculares, Facultad de Medicina, Pontificia Universidad Católica, Santiago de Chile. afajuri@puc.cl
Guarda
E
E
Vergara
I
I
Fernández
S
S
Olea
E
E
Martínez
A
A
Jalil
J
J
Dubernet
J
J
Chamorro
G
G
Rodríguez
J A
JA
González
R
R
Cambón
A M
AM
D000328:Adult; D000368:Aged; D002302:Cardiac Output; D002303:Cardiac Output, Low / Q000503:physiopathology; D002311:Cardiomyopathy, Dilated / Q000503:physiopathology*; D004599:Electric Stimulation Therapy / Q000009:adverse effects*; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D013997:Time Factors; D016276:Ventricular Function
Efectos cardiovasculares del acortamiento del intervalo AV mediante estimulación eléctrica del corazón en miocardiopatía dilatada.