Discordant splenic uptake of Tc-99m colloid and Tc-99m denatured RBC in candidiasis-endocrinopathy syndrome.
We report discordant splenic uptake of Tc-99m colloid and Tc-99m heat-denatured red blood cells (RBC) which occurred in a 21-year-old female with candidiasis-endocrinopathy syndrome. Tc-99m colloid liver-spleen imaging showed no splenic uptake, suggesting the presence of functional asplenia. A subsequent Tc-99m heat-denatured RBC study clearly revealed a small spleen with preserved sequestrating function. These results may demonstrate that the qualitative dissociation of splenic functions in processing colloid and denatured RBC in functional asplenia: the sequestration function remains while the reticuloendothelial system is impaired.
Aburano
T
T
Department of Radiology, Asahikawa Medical College Hospital, Japan.
Katada
R
R
Shuke
N
N
Yamamoto
W
W
Kawakami
T
T
Makino
I
I
Sato
J
J
Ishikawa
Y
Y
D000328:Adult; D002179:Candidiasis, Cutaneous / Q000000981:diagnostic imaging*; D004912:Erythrocytes; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging; D016884:Polyendocrinopathies, Autoimmune / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D013154:Spleen / Q000000981:diagnostic imaging*; D013577:Syndrome; D013667:Technetium / Q000493:pharmacokinetics; D014018:Tissue Distribution; D015899:Tomography, Emission-Computed, Single-Photon; D014057:Tomography, X-Ray Computed
D019275:Radiopharmaceuticals; D013667:Technetium