Ivermectin toxicosis in a zebra.
A 3-mo-old zebra was accidentally given 2.08 mg ivermectin/kg bw orally. Ataxia, blindness and depression developed within a few hours and resolved with symptomatic and supportive treatment by the fifth day post-exposure. These effects were similar to those reported in horses, including the temporary blindness.
Hautekeete
L A
LA
ASPCA/National Animal Poison Control Center, Urbana, IL 61801, USA.
Khan
S A
SA
Hales
W S
WS
D000818:Animals; D000871:Anthelmintics / Q000506:poisoning*; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001259:Ataxia / Q000662:veterinary; D001766:Blindness / Q000662:veterinary; D003002:Clonixin / Q000031:analogs & derivatives / Q000627:therapeutic use; D003907:Dexamethasone / Q000627:therapeutic use; D062787:Drug Overdose / Q000662:veterinary; D018397:Equidae; D005947:Glucose / Q000627:therapeutic use; D006734:Horse Diseases / Q000139:chemically induced* / Q000628:therapy; D006736:Horses; D007559:Ivermectin / Q000506:poisoning*; D008297:Male
D000871:Anthelmintics; D000893:Anti-Inflammatory Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D007559:Ivermectin; D003907:Dexamethasone; C014558:flunixin meglumine; D005947:Glucose; D003002:Clonixin