title: Colour Doppler sonography in breast tumours: an update.
abstract: The aim of our study was to reassess the diagnostic performance of image-based, computer-assisted colour Doppler quantification under routine conditions. We used a computer-assisted protocol that quantitatively characterises a colour Doppler image by the relative amount of colour pixels (colour pixel density, CPD) and the colour hues (numerically expressed by the mean colour value, MCV) in 44 patients with breast carcinoma and 49 patients with benign breast lesions. Studies were carried out over two periods by two examiners, subsequently in charge of breast ultrasound. During the first period, the sensitivity of the MCV was 92 %, the specificity 75 %; the sensitivity of the CPD was 80 %, the specificity 81 %. During the second period, the sensitivity of the MCV was 58 %, the specificity 77 %; the sensitivity of the CPD was 68 %, the specificity 71 %. Despite measures to create uniform examination conditions, the diagnostic performance of this method may decline under routine conditions.
authors.affiliation: Department of Oncologic Diagnostic and Therapy, German Cancer Research Centre, Im Neuenheimer Feld 280, D-69 120 Heidelberg Germany.
authors.forename: S
authors.initials: S
authors.lastname: Delorme
authors.forename: I
authors.initials: I
authors.lastname: Zuna
authors.forename: S
authors.initials: S
authors.lastname: Huber
authors.forename: B
authors.initials: B
authors.lastname: Albert
authors.forename: M L
authors.initials: ML
authors.lastname: Bahner
authors.forename: H
authors.initials: H
authors.lastname: Junkermann
authors.forename: G
authors.initials: G
authors.lastname: van Kaick
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D018615:Ultrasonography, Doppler, Color; D016217:Ultrasonography, Mammary