[Hydrocortisol, parathyroid hormone and calcitonin in blood of patients with chronic pyelonephritis and nephrosclesosis].
Hydrocortisole, parathyroid hormone (PTH), and calcitonin were radioimmunoassayed in the blood of patients with chronic pyelonephritis. Hydrocortisone content decreased at the early stages of nephrosclerosis before renal failure, and hypercalcitoninemia was developing. In chronic renal insufficiency hydrocortisone level normalized, hypercalcitoninemia augmented, and PTH level in the blood plasma increased. Disorders of these substances metabolism are believed to be one factor in the pathogenesis of pyelonephritic nephrosclerosis. Measurements of blood hydrocortisone and calcitonin in patients with chronic pyelonephritis can be used for early diagnosis of nephrosclerosis before its clinical manifestation as chronic pyelonephritis. Such measurements will help objectively assess the activity of the sclerotic process, timely begin proper treatment, and predict the disease course and outcome.
Pavlov
S B
SB
D000328:Adult; D000368:Aged; D015415:Biomarkers; D002116:Calcitonin / Q000097:blood*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009400:Nephrosclerosis / Q000097:blood* / Q000150:complications; D010281:Parathyroid Hormone / Q000097:blood*; D011704:Pyelonephritis / Q000097:blood* / Q000150:complications
D015415:Biomarkers; D010281:Parathyroid Hormone; D002116:Calcitonin; D006854:Hydrocortisone
Soderzhanie kortizola, paratiroĭdnogo gormona i kal'tsitonina v krovi bol'nykh khronicheskim pielonefritom pri razvitii nefroskleroza.