title: [Smooth-muscle-cell tumors of the gastroenteric tract. A review of cases].
abstract: Smooth muscle tumors of the gastrointestinal tract are difficult to evaluate and to stage. Twenty-four patients surgically treated during the last ten years have been evaluated using a TGM staging to identify the more rational criteria for the therapeutic choice. Six gastric leiomyomas, 1 ileal leiomyoma, 4 gastric leiomyosarcomas, 1 esophageal leiomyosarcoma, 4 ileal leiomyosarcomas, 2 rectal leiomyosarcomas and 6 gastric leiomyoblastomas were included. 62.5% of cases presented acute clinical features. Preoperative histological diagnosis was adequate in 29% of cases. We performed 7 excisions, 6 gastric subtotal resections, 3 total gastrectomies, 1 esophageal resection, 5 ileal resections, 2 rectal low anterior resection. Fourteen patients were staged I/II, 8 staged III and 2 staged IV. The overall median survival time was 27.5 months (56, 20 and 5 months concerning stage I/II, III and IV respectively; p < 0.01). In relation to T and G factors overall survival was statistically significant. TGM staging was highly significant to predict long-term survival. Radical surgical procedure was highly effective to guarantee long-term survival. Extended follow up is requested because recurrences after many years seem to be possible also with low histologic grade at first presentation.
authors.affiliation: Istituto di Chirurgia d'Urgenza, Ospedale Maggiore IRCCS, Università degli Studi, Milano.
authors.forename: O
authors.initials: O
authors.lastname: Chiara
authors.forename: T
authors.initials: T
authors.lastname: Canini
authors.forename: M
authors.initials: M
authors.lastname: Segala
authors.forename: G A
authors.initials: GA
authors.lastname: Tiberio
authors.forename: S M
authors.initials: SM
authors.lastname: Giulini
authors.forename: G
authors.initials: G
authors.lastname: Tiberio
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D005770:Gastrointestinal Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology / Q000601:surgery; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000401:mortality / Q000473:pathology / Q000601:surgery; D009367:Neoplasm Staging; D018235:Smooth Muscle Tumor / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology / Q000601:surgery
vernacular_title: I tumori a cellule muscolari lisce del tratto gastroenterico. Revisione casistica.