Lewis antigens as a possible cause of sudden death of previously healthy adults and infants and of diseases and phenomena linked to tissue ischemia.
In persons with anti-Lewis antibodies, erythrocyte agglutination might take place during breathing of odors from secretors of Lewis antigens. The agglutinates occlude capillary vessels, increasing resistance to blood flow. This might lead to the sudden death of adults, sudden infant death syndrome or to diseases accompanied by tissue ischemia, such as migraine, glaucoma, epilepsy, etc.
Grzeszczuk
J
J
D000328:Adult; D002196:Capillaries / Q000502:physiology; D003645:Death, Sudden / Q000209:etiology*; D004912:Erythrocytes / Q000502:physiology; D006384:Hemagglutination; D006461:Hemolysis; D006801:Humans; D007223:Infant; D007511:Ischemia / Q000401:mortality / Q000503:physiopathology*; D007983:Lewis Blood Group Antigens; D008954:Models, Biological; D009812:Odorants; D013398:Sudden Infant Death / Q000209:etiology*
D007983:Lewis Blood Group Antigens