[The regulation of microecological disorders of the intestines in newborn infants with perinatal pathology using the new probiotic bifidumbacterin-forte].
The study was made on 93 newborn infants with perinatal pathology, among them infants with the perinatal lesion of the central nervous system (52), hemolytic disease of newborns (19) and conjugation jaundice (12). All newborn infants were examined for the presence of intestinal microflora in its dynamics and for the state microbiocenosis, evaluated by the rapid method based on the determination of the caseinolytic activity of fecal supernatants after the correction of normal flora with bifidumbacterin in 55 infants and with bifidumbacterin-forte in 38 infants. The comparative study of these two preparations revealed that the use of probiotics containing Bifidobacterium bifidum was mainly substitutional, promoting the colonization of the intestine by lactobacteria, which later determined the suppression opportunistic microflora. The effectiveness of bifidumbacterin-forte containing live B. bifidum, immobilized on sorbent, proved to be most pronounced.
Iakushenko
M N
MN
Kabardin-Balkar University, Nalchik, Russia.
Tkhagapsoeva
Zh M
ZhM
Bondarenko
V M
VM
D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001644:Bifidobacterium; D001688:Biological Products / Q000627:therapeutic use*; D004341:Drug Evaluation; D005243:Feces / Q000382:microbiology; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000188:drug therapy* / Q000382:microbiology; D007422:Intestines / Q000382:microbiology*; D019936:Probiotics / Q000627:therapeutic use*; D013997:Time Factors
D000900:Anti-Bacterial Agents; D001688:Biological Products; C010546:bifidobacterin
Reguliatsiia mikroékologicheskikh narusheniĭ kishechnika u novorozhdennykh deteĭ s perinatal'noĭ patologieĭ novym probiotikom bifidumbakterinom-forte.