[Immediate and long-term results of combined therapy of patients with endometrial neoplasms depending on the effect of counter-suppression of blood lymphocytes].
The short-term (wound healing) and end-results (relapse and metastasis frequency, duration of relapse-free survival and 2-, 3- and 5-year survival) of combined treatment (surgery + gamma therapy) of 97 patients with endometrial carcinoma (stage I-II and stage III-IV) (FIGO, 1988) versus the effect of preoperative counter-suppression of blood lymphocytes were investigated. Both short-term and end-results appeared to be much better in patients showing the counter-suppression effect; they were much worse in patients who revealed the effect prior to combined therapy, and still worse--in cases of inverse effect involving enhanced suppression. It is suggested that the effect of blood lymphocyte counter-suppression before combined treatment is a factor of favorable prognosis in patients with endometrial carcinoma.
Adamian
R T
RT
V.A.Fanarjuan Center for Oncology Research, Yerevan.
Gambarov
S S
SS
Movsesian
M A
MA
Markosian
K M
KM
D003131:Combined Modality Therapy; D018572:Disease-Free Survival; D016889:Endometrial Neoplasms / Q000276:immunology* / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D005260:Female; D006801:Humans; D008214:Lymphocytes; D011379:Prognosis; D016019:Survival Analysis; D016896:Treatment Outcome; D014945:Wound Healing
Blizhaĭshie i otdalënnye rezul'taty kombinirovannogo lecheniia bol'nykh rakom tela matki v zavisimosti ot éffekta kontrasupressii limfotsitov krovi.