title: Evolving clinical strategies: innovative approaches to the use of mitoxantrone--introduction.
abstract: New clinical strategies and innovative approaches to the use of mitoxantrone include high-dose treatment, new combinations such as 5-fluorouracil with leucovorin (NFL), and neoadjuvant therapy for metastatic and primary breast cancer. Its use in other malignancies such as acute leukaemia and low-grade non-Hodgkin's lymphoma are also areas of significant development.
authors.affiliation: Royal Marsden Hospital, Sutton, Surrey.
authors.forename: T J
authors.initials: TJ
authors.lastname: Powles
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000556:secondary; D005260:Female; D006801:Humans; D007938:Leukemia / Q000188:drug therapy*; D008223:Lymphoma / Q000188:drug therapy*; D008942:Mitoxantrone / Q000627:therapeutic use*
chemical_list: D000970:Antineoplastic Agents; D008942:Mitoxantrone