Binding of ATP-sensitive potassium channel (KATP) openers to cardiac membranes: correlation of binding affinities with cardioprotective and smooth muscle relaxing potencies.
Atwal
K S
KS
Bristol-Myers Squibb Pharmaceutical Research Institute, Princeton, New Jersey 08543-4000, USA.
Grover
G J
GJ
Lodge
N J
NJ
Normandin
D E
DE
Traeger
S C
SC
Sleph
P G
PG
Cohen
R B
RB
Bryson
C C
CC
Dickinson
K E
KE
D018528:ATP-Binding Cassette Transporters; D000818:Animals; D002316:Cardiotonic Agents / Q000737:chemistry / Q000494:pharmacology*; D004285:Dogs; D054086:KATP Channels; D009126:Muscle Relaxation / Q000187:drug effects; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology; D009206:Myocardium / Q000378:metabolism*; D015221:Potassium Channels / Q000819:agonists* / Q000378:metabolism; D024661:Potassium Channels, Inwardly Rectifying; D011485:Protein Binding; D013329:Structure-Activity Relationship
D018528:ATP-Binding Cassette Transporters; D002316:Cardiotonic Agents; D054086:KATP Channels; D015221:Potassium Channels; D024661:Potassium Channels, Inwardly Rectifying; C092520:uK-ATP-1 potassium channel