title: Popliteal vein reflux reduces the healing of chronic venous ulcer.
abstract: BACKGROUND
  The relationship between deep and superficial venous reflux and healing of venous ulceration by non-operative compression therapy has not been studied previously.
  
  
  METHODS
  A total of 155 patients with chronic venous ulcers underwent duplex ultrasonography before treatment with compression bandaging at a hospital-based venous clinic.
  
  
  RESULTS
  At 24 weeks, 104 (67 per cent) of ulcers had healed. There was no significant difference in the pattern of either deep or superficial venous reflux between healed and non-healed ulcers except with respect to the popliteal vein. In healed ulcers, 39 scans (38 per cent) indicated competence of the above-knee popliteal vein compared with five (10 per cent) in the non-healing group (P < 0.001, chi 2 test). Similarly, 43 scans (42 per cent) showed below-knee popliteal vein competence in the healed ulcers compared with only five (10 per cent) performed in legs remaining ulcerated (P < 0.001, chi 2 test).
  
  
  CONCLUSIONS
  Popliteal vein incompetence is an indicator of poor response to compression therapy for venous ulceration.
authors.affiliation: University Department of Surgery, Royal Infirmary, Edinburgh, UK.
authors.forename: J
authors.initials: J
authors.lastname: Brittenden
authors.forename: A W
authors.initials: AW
authors.lastname: Bradbury
authors.forename: P L
authors.initials: PL
authors.lastname: Allan
authors.forename: R J
authors.initials: RJ
authors.lastname: Prescott
authors.forename: D R
authors.initials: DR
authors.lastname: Harper
authors.forename: C V
authors.initials: CV
authors.lastname: Ruckley
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001458:Bandages; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016491:Peripheral Vascular Diseases / Q000503:physiopathology; D011152:Popliteal Vein; D018608:Ultrasonography, Doppler; D014647:Varicose Ulcer / Q000503:physiopathology* / Q000628:therapy; D014689:Venous Insufficiency / Q000503:physiopathology; D014945:Wound Healing