title: The impact of current use of hormone replacement therapy on prognostic factors and surgical treatment of new breast cancers.
abstract: When postmenopausal women were diagnosed with breast cancer while taking hormone replacement, no adverse effects were noted in either clinical or prognostic factors when compared to a similar group not on hormones. Younger age at diagnosis and an increased chance of carcinoma in situ were noted in those on hormones. A surveillance or observational bias is one explanation for these findings. A promotional effect of hormone replacement therapy could not be eliminated based on this study.
authors.affiliation: The Breast Center, New Orleans, LA 70115, USA.
authors.forename: A J
authors.initials: AJ
authors.lastname: Stolier
authors.forename: R
authors.initials: R
authors.lastname: Mera
authors.forename: D
authors.initials: D
authors.lastname: Schapira
mesh_terms: D000367:Age Factors; D000368:Aged; D001943:Breast Neoplasms / Q000473:pathology / Q000601:surgery*; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010052:Ovariectomy; D017698:Postmenopause; D011379:Prognosis; D011960:Receptors, Estrogen / Q000032:analysis; D011980:Receptors, Progesterone / Q000032:analysis
chemical_list: D011960:Receptors, Estrogen; D011980:Receptors, Progesterone