title: [Large volume lymphocytapheresis for the collection of peripheral stem cells].
abstract: We performed 29 large-volume leukaphereses of 20 patients for collection of peripheral blood stem cells. All patients have been pretreated with cytokines after chemotherapy. In 9 patients with precounts of > or = 3 x 10(9) mononuclear cells/l we achieved a sufficient transplantation doses with one LVL. If the MNC precount was < or = 3 x 10(9)/l we had to perform more than one LVL. On 16 patients we compared a standard apheresis procedure with the LVL procedure. It seems that especially patients with a lower MNC precount can profit from LVL. From patients with higher MNC precounts we harvested the double amount of MNCs, from patients with lower MNC precounts the triple amount.
authors.affiliation: Institut für Transfusionsmedizin, Universitätsklinikum Charité, Humboldt-Universität zu Berlin, Deutschland.
authors.forename: I
authors.initials: I
authors.lastname: Pawlow
authors.forename: E
authors.initials: E
authors.lastname: Richter
authors.forename: G
authors.initials: G
authors.lastname: Matthes
authors.forename: E
authors.initials: E
authors.lastname: Rath
authors.forename: W
authors.initials: W
authors.lastname: Schultze
mesh_terms: D005260:Female; D006412:Hematopoietic Stem Cells; D006801:Humans; D007937:Leukapheresis / Q000295:instrumentation / Q000379:methods*; D007938:Leukemia / Q000628:therapy; D008214:Lymphocytes; D008223:Lymphoma / Q000628:therapy; D008297:Male; D009369:Neoplasms / Q000628:therapy*
vernacular_title: Grossvolumige Lymphozytapherese zur Sammlung peripherer Stammzellen.