title: [Efficacy of pefloxacin in the treatment of complicated relapsing erysipelas].
abstract: The effect of antimicrobial agents on the clinical and immunological indices was comparatively studied in 30 patients with relapsing erysipelas complicated by pyoderma. The patients were treated with pefloxacin in a daily dose of 800 mg for 7-10 days (15 patients) and with the routine antibiotics such as benzylpenicillin, ampicillin and erythromycin (15 patients). The efficacy of the treatment was defined by disappearance of the clinical signs and normalization of the functional immunity status. The pefloxacin effect was evident at early stages of the treatment and observed at least for 3 months after the patient discharge from the hospital. Gradual elimination of the secondary immune deficiency in the convalescents due to sanitation of the infection chronic foci was recorded.
authors.affiliation: Institute of Advanced Medical Training, Kazakh State Medical University, Alma-Ata.
authors.forename: K B
authors.initials: KB
authors.lastname: Kurmanova
authors.forename: Z I
authors.initials: ZI
authors.lastname: Sulełmenova
authors.forename: K
authors.initials: K
authors.lastname: Sensatkhit
authors.forename: M N
authors.initials: MN
authors.lastname: Uteulin
mesh_terms: D000368:Aged; D000667:Ampicillin / Q000008:administration & dosage / Q000627:therapeutic use; D000890:Anti-Infective Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D015703:Antigens, CD / Q000276:immunology; D004359:Drug Therapy, Combination / Q000008:administration & dosage / Q000627:therapeutic use*; D004886:Erysipelas / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D004917:Erythromycin / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D007136:Immunoglobulins / Q000276:immunology; D008297:Male; D008875:Middle Aged; D010351:Patient Discharge; D015366:Pefloxacin / Q000008:administration & dosage / Q000627:therapeutic use*; D010400:Penicillin G / Q000008:administration & dosage / Q000627:therapeutic use; D011711:Pyoderma / Q000150:complications / Q000188:drug therapy* / Q000276:immunology; D013211:Staphylococcus aureus / Q000187:drug effects; D013297:Streptococcus pyogenes / Q000187:drug effects; D013601:T-Lymphocytes / Q000276:immunology
chemical_list: D000890:Anti-Infective Agents; D015703:Antigens, CD; D007136:Immunoglobulins; D015366:Pefloxacin; D004917:Erythromycin; D000667:Ampicillin; D010400:Penicillin G
vernacular_title: 'Effektivnost' pefloksatsina pri oslozhnennom techenii retsidiviruiushcheł rozhi.