title: [Strain-specific antibodies to wild poliomyelitis viruses as an index of the circulation of these viruses in a surveyed territory].
abstract: In response to vaccination or infection with wild poliovirus, some children can finely differentiate the virus structure and respond by forming strain-specific antibodies. The analysis of strain-specific antibodies indicates that in epidemically unfavorable regions strain-specific antibodies to wild poliovirus strains may prevail over those to vaccine poliovirus strains in children or occur with equal frequency. In epidemically favourable regions strain-specific antibodies to vaccine poliovirus strain significantly prevail in children or may be absent at all. The analysis of strain-specific antibodies makes it possible to retrospectively judge on the circulation of wild viruses in the surveyed region.
authors.affiliation: Chumakov Institute of Poliomyelitis and Viral Encephalitis, Moscow, Russia.
authors.forename: V B
authors.initials: VB
authors.lastname: Seĭbil'
authors.forename: L P
authors.initials: LP
authors.lastname: Malyshkina
authors.forename: I K
authors.initials: IK
authors.lastname: Lavrova
authors.forename: S G
authors.initials: SG
authors.lastname: Drozdov
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D000918:Antibody Specificity / Q000276:immunology*; D002648:Child; D003588:Cytopathogenic Effect, Viral; D004197:Disease Reservoirs; D006801:Humans; D009500:Neutralization Tests; D017955:Poliovirus / Q000276:immunology*; D011054:Poliovirus Vaccine, Inactivated / Q000276:immunology; D012189:Retrospective Studies; D013045:Species Specificity; D014610:Uzbekistan
chemical_list: D000914:Antibodies, Viral; D011054:Poliovirus Vaccine, Inactivated
vernacular_title: Shtammospetsficheskie antitela k dikim virusam poliomielita kak pokazatel' tsirkuliatsii étikh virusov na obsleduemoĭ territorii.