title: [Intravascular ultrasound findings in calcifying arteriosclerosis: in vitro validation using "soft" roentgen images].
abstract: OBJECTIVE
  The aim of this study was to validate the detection of calcified arteriosclerotic plaques with intravascular ultrasound (IVUS).
  
  
  METHODS
  181 arteries were examined by 20/30 MHz IVUS. The ultrasound cross-sections were compared to the corresponding radiologic (30 kV) and histologic cross-sections.
  
  
  RESULTS
  Calcified lesions were imaged as bright echos with shadowing. In 13 cases of 161 calcified lesions were too small to detect by IVUS. In 5 ultrasonic sections the diagnosis "calcified lesion" could not be verified neither by radiology nor by histology. The sensitivity was 91.6%, the specificity was 94.7% and the accuracy was 93.0%.
  
  
  CONCLUSIONS
  Because of the acoustic properties of calcium, calcified lesions can be detected accurately by IVUS. IVUS can generate new insights into the effect of plaque composition on the response to catheter therapies.
authors.affiliation: Abteilung für Biomedizinische Technik, Ruhr-Universität Bochum.
authors.forename: M
authors.initials: M
authors.lastname: Meine
authors.forename: A
authors.initials: A
authors.lastname: Machraoui
authors.forename: G
authors.initials: G
authors.lastname: Dasbach
authors.forename: B
authors.initials: B
authors.lastname: Lemke
authors.forename: S
authors.initials: S
authors.lastname: Dryander
authors.forename: K M
authors.initials: KM
authors.lastname: Müller
authors.forename: J
authors.initials: J
authors.lastname: Barmeyer
mesh_terms: D000368:Aged; D001158:Arteries / Q000000981:diagnostic imaging; D001161:Arteriosclerosis / Q000000981:diagnostic imaging*; D002114:Calcinosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D066298:In Vitro Techniques; D008297:Male; D008875:Middle Aged; D008955:Models, Cardiovascular; D019047:Phantoms, Imaging; D012680:Sensitivity and Specificity; D018084:Ultrasonography, Interventional
vernacular_title: Intravasale Ultraschallbefunde bei kalzifizierender Arteriosklerose: In-vitro-Validierung mittels "weicher" Röntgenstrahlaufnahmen.