[Detection of Epstein-Barr virus DNA in malignant lymphomas].
The etiology of malignant lymphomas is unknown, but certain evidence imply the possibility of Epstein-Barr virus connection to this disease. The presence of Epstein-Barr viral DNA in 95 patients with malignant lymphomas (49 patients with Hodgkin's disease and 46 patients with non-Hodgkin's lymphomas) was investigated by method of in situ hybridization. Viral DNA was proved in 30.53% patients with malignant lymphomas: in 38.78% of patients with Hodgkin's disease and 21.74% patients with non-Hodgkin's lymphomas. Those facts point out that Epstein-Barr virus is one of the possible carcinogens involved in those tumors growth.
Kuljić-Kapulica
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Vojnomedicinska akademija, ZPM-Institut za mikrobiologiju, Beograd.
D000293:Adolescent; D000328:Adult; D000368:Aged; D004279:DNA, Viral / Q000032:analysis*; D004854:Herpesvirus 4, Human / Q000302:isolation & purification*; D006801:Humans; D008223:Lymphoma / Q000821:virology*; D008875:Middle Aged
D004279:DNA, Viral
Detekcija DNK Epstein-Barr-ovog virusa u malignim limfomima.