title: Pregnancy resulting from frozen-thawed embryos achieved by intracytoplasmic injection of cryopreserved sperm cells extracted from an orchidectomized, seminoma-bearing testis, causing obstructive azoospermia.
abstract: A clinical pregnancy occurred in a 26-year-old patient after transfer of frozen-thawed embryos had been achieved by intracytoplasmic sperm injection (ICSI) of cryopreserved spermatozoa. These had been obtained from a testis removed due to seminoma. The couple applied to our fertility clinic for sperm cryopreservation before orchidectomy and radiotherapy. Unfortunately the husband was found to be azoospermic upon admission and sperm cells were extracted from the removed testis for use in our ICSI programme. This case represents a new aetiology for obstructive azoospermia that was successfully treated by ICSI. A pregnancy was established, resulting in successful birth.
authors.affiliation: The Institute for the Study of Fertility, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Israel.
authors.forename: H
authors.initials: H
authors.lastname: Yavetz
authors.forename: R
authors.initials: R
authors.lastname: Hauser
authors.forename: A
authors.initials: A
authors.lastname: Botchan
authors.forename: F
authors.initials: F
authors.lastname: Azem
authors.forename: I
authors.initials: I
authors.lastname: Yovel
authors.forename: J B
authors.initials: JB
authors.lastname: Lessing
authors.forename: A
authors.initials: A
authors.lastname: Amit
authors.forename: L
authors.initials: L
authors.lastname: Yogev
mesh_terms: D000328:Adult; D015925:Cryopreservation; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008845:Microinjections; D009845:Oligospermia / Q000209:etiology / Q000628:therapy*; D009919:Orchiectomy; D011247:Pregnancy; D011256:Pregnancy Outcome; D011878:Radiotherapy; D018239:Seminoma / Q000150:complications* / Q000473:pathology / Q000628:therapy; D013094:Spermatozoa; D013736:Testicular Neoplasms / Q000150:complications* / Q000473:pathology / Q000628:therapy; D013737:Testis / Q000166:cytology