Acetylcholine reactivates latent pseudorabies virus in mice.
The latency model of pseudorabies virus (PrV) wild strain, YS-81, in mice was established and latent PrV reactivated with acetylcholine. The latent PrV was reactivated from the trigeminal ganglia with acetylcholine. It was found that this model is useful in investigating the mechanism of latent PrV reactivation by acetylcholine.
Tanaka
S
S
Animal Laboratory Center, Oita Medical University, Japan.
Imamura
T
T
Sakaguchi
M
M
Mannen
K
K
D000109:Acetylcholine / Q000494:pharmacology*; D000818:Animals; D002460:Cell Line; D003588:Cytopathogenic Effect, Viral; D004195:Disease Models, Animal; D011558:Herpesvirus 1, Suid / Q000502:physiology*; D051379:Mice; D008807:Mice, Inbred BALB C; D011557:Pseudorabies / Q000821:virology*; D013552:Swine; D012668:Trigeminal Ganglion / Q000821:virology; D014775:Virus Activation; D017735:Virus Latency
D000109:Acetylcholine