title: [Nitric oxide synthase in neuroepithelial brain tumors].
abstract: Immunohistochemical investigation of NO-synthase in brain astrocytic tumors revealed intense reaction in many tumor cells as well as direct correlation in the intensity of reaction and the degree of tumor anaplasia. Grade I astrocytomas did not show immunoreactivity in contrast to high anaplastic tumors where many cells had positive reaction with a different degree of intensity. Positive immunoreaction was shown in many giant cells. Small cell glioblastomas and oligodendrogliomas were immunonegative. There was a direct correlation between NO-synthase expression and glial fibrillar acidic protein.
authors.affiliation: N.P. Ogarev Mordovian State University, Saransk, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Sosunov
authors.forename: I N
authors.initials: IN
authors.lastname: Chairkin
authors.forename: L R
authors.initials: LR
authors.lastname: Odyvanova
authors.forename: G
authors.initials: G
authors.lastname: Guski
authors.forename: D Zh
authors.initials: DZh
authors.lastname: Tservos-Navarro
mesh_terms: D001254:Astrocytoma / Q000201:enzymology*; D001932:Brain Neoplasms / Q000201:enzymology*; D005909:Glioblastoma / Q000201:enzymology*; D006801:Humans; D007150:Immunohistochemistry; D019001:Nitric Oxide Synthase / Q000032:analysis*
chemical_list: D019001:Nitric Oxide Synthase
vernacular_title: Sintaza okisi azota v neĭroépitelial'nykh opukholiakh golovnogo mozga.