[Lupus erythematosus: effects of different therapeutic methods on intranuclear characteristics of lymphoid cells].
In lymphocytes of peripheral blood from 46 patients with various forms of lupus erythematosus measurements were made of histone fractions and DNA. It is proved that intranuclear characteristics of lymphoid cells can be used in the choice of treatment and assessment of its efficacy. Lupus erythematosus treatment with glucocorticoids (diprospan, diprospan + celeston) is effective in correction of intranuclear lymphocyte changes in this disease.
Khamaganova
I V
IV
Savina
M I
MI
Khromova
S S
SS
Reshina
V M
VM
Aleĭnikova
N V
NV
D000293:Adolescent; D000328:Adult; D002455:Cell Division; D002467:Cell Nucleus / Q000737:chemistry / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D004247:DNA / Q000032:analysis; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006657:Histones / Q000032:analysis; D006801:Humans; D008179:Lupus Erythematosus, Discoid / Q000097:blood / Q000628:therapy; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000628:therapy*; D008214:Lymphocytes / Q000187:drug effects / Q000378:metabolism / Q000473:pathology*; D008280:Magnetics / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged
D005938:Glucocorticoids; D006657:Histones; D004247:DNA
Vliianie razlichnykh metodov lecheniia krasnoĭ volchanki na vnutriiadernye kharakteristiki limfoidnykh kletok.