Angiotropic large cell lymphoma which infiltrated to the adrenal glands presenting as reversible adrenal insufficiency.
A 72-year-old man who suffered from recurrent fever was found to have enlarged bilateral adrenal glands on computed tomographic scanning, combined with subclinical adrenal insufficiency. Based on the pathology of bone marrow aspiration, he was diagnosed to have an angiotropic large cell lymphoma (ALCL). Soon after the treatment with a combination chemotherapy, he achieved complete remission of ALCL and size and function of the adrenal glands were apparently normalized. ALCL should be included in the list of differential diagnoses of non-functioning bilateral adrenal swelling with non-specific symptoms such as fever.
Kuwahara
K
K
Endocrine Service and Division of Hematology, Shizuoka City Hospital, Shizuoka.
Fukata
J
J
Kamio
M
M
Mochizuki
T
T
Tsuchiya
A
A
Tanaka
S
S
D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D000309:Adrenal Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage; D001853:Bone Marrow / Q000473:pathology; D003520:Cyclophosphamide / Q000008:administration & dosage; D003937:Diagnosis, Differential; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D011241:Prednisone / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000008:administration & dosage
D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011241:Prednisone