Endogenous cortisol profile in patients with central serous chorioretinopathy.
OBJECTIVE
To study the endogenous cortisol levels in patients with central serous chorioretinopathy (CSCR).


METHODS
Endogenous cortisol levels in urine and plasma were determined in 30 patients with acute CSCR and compared with 30 age and sex matched controls.


RESULTS
The mean values of the 8 am plasma cortisol (29.97 micrograms/dl v 18.76 micrograms/dl), 11 pm plasma cortisol (22.03 micrograms/dl v 13.06 micrograms/dl), and 24 hour urine cortisol (11.01 mg/24 h v 7.39 mg/24 h) revealed significantly higher values in the patient group (p < 0.001).


CONCLUSIONS
Increased levels of endogenous cortisol are present in patients with CSCR.
Garg
S P
SP
Dr R P Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India.
Dada
T
T
Talwar
D
D
Biswas
N R
NR
D000328:Adult; D015415:Biomarkers / Q000032:analysis / Q000097:blood / Q000652:urine; D016022:Case-Control Studies; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis* / Q000097:blood / Q000652:urine; D008297:Male; D012164:Retinal Diseases / Q000378:metabolism*; D014792:Visual Acuity
D015415:Biomarkers; D006854:Hydrocortisone