title: Endoscopic resection of gastrointestinal submucosal tumors.
abstract: OBJECTIVE
  The occurrence of submucosal tumors in the gastrointestinal tract is not infrequent. According to endoscopic pictures, submucosal tumors can usually be diagnosed without difficulty. However, even with the aid of endoscopic ultrasound, a definite diagnosis is not possible without histological results. Before endoscopy became available, the treatment strategy for gastrointestinal submucosal tumors was either surgery or observation. Due to advances in scientific technology, endoscopic treatment of gastrointestinal submucosal tumors has become increasingly popular. In reviewing the literature, we found that only case reports or small series reports detailing specific tumors in specific locations existed previously.
  
  
  METHODS
  Endoscopic resection for 12 gastrointestinal submucosal tumors in 11 patients has been successfully performed in our hospital during the past three years.
  
  
  RESULTS
  The group included 5 men and 6 women, ranging in age from 28 to 78 years. The locations of the tumors consisted of 1 in the esophagus, 2 in the stomach, 1 in the jejunum, 5 in the colon and 3 in the rectum. Histological results showed 3 lipomas, 3 carcinoids, 2 leiomyomas, 1 ganglioneuromatous polyp, 1 hemangioma, 1 inflammatory fibroid polyp and 1 myomatous hyperplasia. Bleeding complications occurred in only 2 cases. One stopped spontaneously and the other stopped after epinephrine and sclerosant injection. Only 1 case required a two-step resection in order to avoid perforation. No tumor recurrence was noted during the follow-up period, which ranged from 2 months to 3 years.
  
  
  CONCLUSIONS
  In suitable cases, endoscopic resection of gastrointestinal submucosal tumors can be a safe and valuable method for treating symptomatic tumors and obtaining histological diagnosis of the submucosal tumors.
authors.affiliation: Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan, R.O.C.
authors.forename: S C
authors.initials: SC
authors.lastname: Wei
authors.forename: J M
authors.initials: JM
authors.lastname: Wong
authors.forename: M J
authors.initials: MJ
authors.lastname: Shieh
authors.forename: C T
authors.initials: CT
authors.lastname: Sun
authors.forename: C Y
authors.initials: CY
authors.lastname: Wang
authors.forename: T H
authors.initials: TH
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D004724:Endoscopy; D016099:Endoscopy, Gastrointestinal; D005260:Female; D005770:Gastrointestinal Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged