Functional MR imaging of cortical activation of the cerebral hemispheres during motor tasks.
OBJECTIVE
We used functional MR imaging to evaluate cortical activation in the precentral, central, and postcentral regions of the contralateral and ipsilateral cerebral hemispheres during left- and right-handed motor tasks.


METHODS
Ten healthy right-handed volunteers were studied with echo-planner MR imaging (1.5 T) while performing alternating finger apposition tasks with both hands. During the hand tasks, the areas of activated pixels were compared between subregions (precentral, central, and postcentral) of the contralateral and ipsilateral sensorimotor cortex.


RESULTS
The activated area of the contralateral sensorimotor cortex was significantly larger than that of the ipsilateral cortex during tasks with either hand, whereas the ipsilateral activated area was significantly larger during the left-handed task than during the right-handed task. Ipsilateral activation was greatest in the precentral region, less in the central region, and least prominent in the postcentral region.


CONCLUSIONS
Our results confirmed those of previous investigators that ipsilateral activation is more pronounced during left-sided movements than during right-sided movements. The variation in activation of the precentral, central, and postcentral subregions suggests different roles of the ipsilateral and contralateral hemispheres during motor tasks.
Singh
L N
LN
Department of Radiology, Tohoku University School of Medicine, Sendai, Japan.
Higano
S
S
Takahashi
S
S
Abe
Y
Y
Sakamoto
M
M
Kurihara
N
N
Furuta
S
S
Tamura
H
H
Yanagawa
I
I
Fujii
T
T
Ishibashi
T
T
Maruoka
S
S
Yamada
S
S
D000328:Adult; D001143:Arousal / Q000502:physiology*; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000502:physiology*; D004292:Dominance, Cerebral / Q000502:physiology; D005260:Female; D007839:Functional Laterality / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009044:Motor Cortex / Q000502:physiology; D009048:Motor Skills / Q000502:physiology*; D012016:Reference Values; D013003:Somatosensory Cortex / Q000502:physiology