title: Hepatic nodules as single organ involvement in an adult with Langerhans cell granulomatosis. A case report.
abstract: Liver involvement manifesting as hepatomegaly in Langerhans cell granulomatosis (LCG) is well known, but the definitive diagnosis is generally possible because other organs are involved. We report a 41-year-old white man who presented with cholestasis and liver nodules as an isolated hepatic LCG. The diagnosis of LCG was suspected based on routine histopathologic examination; the diagnosis became definitive 4 years later when Birbeck granules were found in the liver, an uncommon occurrence in this organ. This is an unusual presentation of a benign form of this disease and one of the first that reported Birbeck granules in the liver.
authors.affiliation: Department of Hepato-Gastroenterology, Amiens Hospital, France.
authors.forename: S
authors.initials: S
authors.lastname: Lévy
authors.forename: D
authors.initials: D
authors.lastname: Capron
authors.forename: J P
authors.initials: JP
authors.lastname: Joly
authors.forename: C
authors.initials: C
authors.lastname: Cordonnier
authors.forename: H
authors.initials: H
authors.lastname: Sevestre
authors.forename: J
authors.initials: J
authors.lastname: Delamarre
authors.forename: B
authors.initials: B
authors.lastname: Tribout
authors.forename: J P
authors.initials: JP
authors.lastname: Capron
mesh_terms: D000328:Adult; D006529:Hepatomegaly / Q000209:etiology / Q000473:pathology; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications*; D006801:Humans; D008107:Liver Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology*; D008297:Male; D011859:Radiography; D014463:Ultrasonography