Immunomodulating and antiviral therapy in herpes zoster.
Two groups of patients with herpes zoster were followed up. The first group was subjected, beside a symptomatic therapy, to an immunological and antiviral treatment. The control group was treated only symptomatically. The immunological preparations used were: the immunostimulant SRE (Corynebacterium parvum), which stimulated the lymphocytes and macrophages, Moroxidin (Virustat-Paris) and Antiherpin (interferon inductor), which acted by blocking the virus replication. The preparations were indigenous and atoxic. A significant difference between the courses of disease in the two groups was observed, namely, the severity and duration of subjective and objective symptoms were more than double and followed by persistent neurological sequelae in the control group in comparison with the patients of the experimental group.
Topciu
V
V
University of Medicine and Pharmacy, Timişoara.
Mihăilescu
R
R
D000276:Adjuvants, Immunologic / Q000008:administration & dosage*; D000956:Antigens, Viral / Q000627:therapeutic use*; D001645:Biguanides; D005500:Follow-Up Studies; D006562:Herpes Zoster / Q000188:drug therapy* / Q000276:immunology; D006801:Humans; D009025:Morpholines / Q000627:therapeutic use*
D000276:Adjuvants, Immunologic; D000956:Antigens, Viral; D001645:Biguanides; D009025:Morpholines; C074145:antiherpin; C005267:moroxydine