Drug-induced acute tubulointerstitial nephritis: the clinical spectrum.
Clinical and laboratory findings vary with the drug involved. A definitive diagnosis requires renal biopsy; a gallium scan may be helpful when biopsy is not feasible. Outcome depends on drug withdrawal, but corticosteroids may be beneficial.
Cruz
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DN
Department of Internal Medicine, Yale University School of Medicine, New Haven, Conn., USA.
Perazella
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MA
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000009:adverse effects*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D000927:Anticonvulsants / Q000009:adverse effects*; D001706:Biopsy; D004232:Diuretics / Q000009:adverse effects*; D005710:Gallium Radioisotopes; D006801:Humans; D009395:Nephritis, Interstitial / Q000139:chemically induced* / Q000175:diagnosis* / Q000188:drug therapy
D000305:Adrenal Cortex Hormones; D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000927:Anticonvulsants; D004232:Diuretics; D005710:Gallium Radioisotopes