Enteroaggregative, Shiga toxin-producing Escherichia coli O111:H2 associated with an outbreak of hemolytic-uremic syndrome.
Shiga toxin-producing Escherichia coli O111:H2 strains from an outbreak of hemolytic-uremic syndrome showed aggregative adhesion to HEp-2 cells and harbored large plasmids which hybridized with the enteroaggregative E. coli probe PCVD432. These strains present a novel combination of virulence factors and might be as pathogenic to humans as the classic enterohemorrhagic E. coli.
Morabito
S
S
Laboratorio di Medicina Veterinaria, Istituto Superiore di Sanità, Rome, Italy.
Karch
H
H
Mariani-Kurkdjian
P
P
Schmidt
H
H
Minelli
F
F
Bingen
E
E
Caprioli
A
A
D001422:Bacterial Adhesion; D001427:Bacterial Toxins / Q000096:biosynthesis*; D003090:Coliphages / Q000235:genetics / Q000502:physiology; D004196:Disease Outbreaks; D004926:Escherichia coli / Q000235:genetics / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology*; D006463:Hemolytic-Uremic Syndrome / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D010957:Plasmids; D022603:Shiga Toxins; D014407:Tumor Cells, Cultured; D014774:Virulence
D001427:Bacterial Toxins; D022603:Shiga Toxins