title: Oral appliance therapy for obstructive sleep apnea syndrome: progressive mandibular advancement during polysomnography.
abstract: Six patients diagnosed with obstructive sleep apnea completed titration of an adjustable oral appliance, called the Silencer, during a single night of polysomnography. This protocol allowed for rapid titration of the oral appliance and effective treatment of sleep apnea. Variables which showed improvement included frequency of obstructive events, oxyhemoglobin saturation and snoring. Dental appliance adjustments with the silencer device can be made within three minutes. We have demonstrated that incremental mandibular advancement and repositioning allow us to determine the most effective jaw position to treat sleep apnea and snoring, which is also most likely to be tolerated by the patient.
authors.affiliation: Greater Washington Sleep Disorders Centers, Rockville, Maryland 20850, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Raphaelson
authors.forename: E J
authors.initials: EJ
authors.lastname: Alpher
authors.forename: K W
authors.initials: KW
authors.lastname: Bakker
authors.forename: J R
authors.initials: JR
authors.lastname: Perlstrom
mesh_terms: D000328:Adult; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D019186:Mandibular Advancement / Q000379:methods*; D008875:Middle Aged; D016382:Orthodontic Appliance Design; D009967:Orthodontic Appliances; D017286:Polysomnography / Q000379:methods*; D012891:Sleep Apnea Syndromes / Q000175:diagnosis / Q000628:therapy*; D012913:Snoring / Q000175:diagnosis / Q000628:therapy