[The role of glucocorticoids at the corticosterone level after stress in the early ontogeny of gray rats].
Norway rats were subjected to stress procedure of saline or hydrocortisone injections. The saline-treated rats revealed an increased level of the plasma corticosterone as opposed to hydrocortisone-treated ones. The modification of adrenocortical function with the stress in early postnatal life seems to be connected with changes in hypothalamic catecholamine synthesis and can be prevented with exogenous glycocorticoids.
Maslova
L N
LN
Institute of Cytology and Genetics, Siberian Branch, Russian Acad. Sci., Novosibirsk, Russia.
Shishkina
G T
GT
Dygalo
N N
NN
Naumenko
E V
EV
D000375:Aging / Q000187:drug effects* / Q000502:physiology; D000818:Animals; D001921:Brain / Q000187:drug effects / Q000503:physiopathology; D003345:Corticosterone / Q000097:blood*; D005938:Glucocorticoids / Q000494:pharmacology*; D006854:Hydrocortisone / Q000494:pharmacology*; D007030:Hypothalamo-Hypophyseal System / Q000187:drug effects / Q000502:physiology; D008297:Male; D010913:Pituitary-Adrenal System / Q000187:drug effects / Q000502:physiology; D051381:Rats; D017983:Receptors, Catecholamine / Q000187:drug effects / Q000502:physiology; D012149:Restraint, Physical; D012641:Selection, Genetic; D013315:Stress, Psychological / Q000097:blood / Q000209:etiology / Q000503:physiopathology*
D005938:Glucocorticoids; D017983:Receptors, Catecholamine; D003345:Corticosterone; D006854:Hydrocortisone
Rol' gliukokortikoidov v urovne kortikosterona posle stressa v rannem ontogeneze u serykh krys.