Characterization in vivo of muscle fiber types by magnetic resonance imaging.
Magnetic resonance imaging has been used to characterize muscle fiber types. Here, T1 and T2 values were determined in pure slow-twitch and fast-twitch rabbit muscles and in rabbit muscles with mixed fiber types. The muscles with high proportions of oxidative slow-twitch fibers had higher T2 values than the others. Echo time, orientation of muscle fibers in B0, and moving spins had no effect on relaxation parameters. The results are discussed in terms of slow myosin isoform content and oxidative metabolism.
Bonny
J M
JM
STIM, INRA-Theix, Saint-Genes-Champanelle, France.
Zanca
M
M
Boespflug-Tanguy
O
O
Dedieu
V
V
Joandel
S
S
Renou
J P
JP
D000251:Adenosine Triphosphatases / Q000032:analysis; D000818:Animals; D002950:Citrate (si)-Synthase / Q000032:analysis; D006614:Hindlimb; D006651:Histocytochemistry; D007770:L-Lactate Dehydrogenase / Q000032:analysis; D008279:Magnetic Resonance Imaging; D018656:Muscle Fibers, Fast-Twitch / Q000166:cytology / Q000201:enzymology; D018485:Muscle Fibers, Skeletal / Q000166:cytology* / Q000201:enzymology; D018657:Muscle Fibers, Slow-Twitch / Q000166:cytology / Q000201:enzymology; D018482:Muscle, Skeletal / Q000033:anatomy & histology; D011817:Rabbits
D007770:L-Lactate Dehydrogenase; D002950:Citrate (si)-Synthase; D000251:Adenosine Triphosphatases