title: [Cardiac changes in children with AIDS].
abstract: OBJECTIVE
  To describe the cardiac findings in children with AIDS, the follow-up with treatment and the correlation between clinical and pathological features.
  
  
  METHODS
  We studied prospectively 25 children with clinical-laboratorial diagnosis of AIDS, ages between 3 months and 11 years, even those without cardiac symptoms. We classified the signs of AIDS following that of CDC-Atlanta 1994. Eight children died and it was done necropsy in six with macro and microscopic examinations.
  
  
  RESULTS
  Fifteen cases had already complications of AIDS and were classified as C2 and C3, 5 as B2, 3 B1 and 2 as A1. Beside the symptoms related to the disease and infections we found signs of congestive heart failure III and IV (NYHA) in 5 children, pericardial effusion in 5, (one of them had cardiac tamponade). In the electrocardiogram (EKG), 8 children had repolarization abnormalities. In 1st echocardiogram (ECHO) we found some features of dilated myocardiopathy in 8 (6 were asymptomatic) 5 of those had pericardial effusion, one child had huge amount of pericardial liquid and also increased measures of intraventricular septum and posterior wall of left ventricle by ECHO and confirmed by necropsy examination. All cases of diagnosis of myocardiopathy received treatment with captopril and 4 also received furosemide and digoxina. Even under oral treatment three of them had deterioration of heart failure but after combined anti-retroviral drugs they showed better cardiac functions. From the six necropsied cases, two had increased heart weight without myocarditis, one had toxoplasma pancarditis and other one had fibrocalcic vasculopathy.
  
  
  CONCLUSIONS
  We found several assymptomatic cases already with decreased ventricular function. Some worsened of heart failure even under apropriate treatment and showed better cardiac index after combined anti-retroviral drugs.
authors.affiliation: Hospital Universitário Antonio Pedro, UFF, Niterói.
authors.forename: G V
authors.initials: GV
authors.lastname: Haddad Herdy
authors.forename: M M
authors.initials: MM
authors.lastname: Leite
authors.forename: V G
authors.initials: VG
authors.lastname: Lopes
authors.forename: C A
authors.initials: CA
authors.lastname: Pinto
authors.forename: J
authors.initials: J
authors.lastname: Barbosa
authors.forename: P A
authors.initials: PA
authors.lastname: Tavares Júnior
authors.forename: A H
authors.initials: AH
authors.lastname: Herdy
authors.forename: P S
authors.initials: PS
authors.lastname: Almeida
authors.forename: R
authors.initials: R
authors.lastname: de Carvalho
authors.forename: P B
authors.initials: PB
authors.lastname: Barros
authors.forename: M B
authors.initials: MB
authors.lastname: Neto
authors.forename: R G
authors.initials: RG
authors.lastname: Ramos
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000175:diagnosis; D002648:Child; D002675:Child, Preschool; D006331:Heart Diseases / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007223:Infant; D011446:Prospective Studies
vernacular_title: Alterações cardíacas em crianças com SIDA.