[The analgesic and antidepressant action of adrenaline-induced stress in the endogenous activation of the gastric afferent systems in rats].
Adrenaline-induced stress as well as exogenous cholecystokinin exerted analgetic, antidepressant, and antistress effect upon depressive rats with high nociceptive sensitivity. The effect seems to be due to stimulation of chemoreceptors of the stomach vagal afferents by means of cholecystokinin secretion into the gastric lumen.
Serdiuk
S E
SE
Medical University, Ilyicha, Ukraine.
Gmiro
V E
VE
D000208:Acute Disease; D000344:Afferent Pathways / Q000187:drug effects / Q000503:physiopathology; D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D002628:Chemoreceptor Cells / Q000187:drug effects / Q000503:physiopathology; D002766:Cholecystokinin / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D004837:Epinephrine; D008297:Male; D051381:Rats; D013270:Stomach / Q000187:drug effects / Q000294:innervation / Q000503:physiopathology*; D013312:Stress, Physiological / Q000139:chemically induced / Q000503:physiopathology*; D014630:Vagus Nerve / Q000187:drug effects / Q000503:physiopathology
D000700:Analgesics; D000928:Antidepressive Agents; D002766:Cholecystokinin; D004837:Epinephrine
Anal'geziruiushchee i antidepressivnoe deĭstvie adrenalinovogo stressa pri éndogennoĭ aktivatsii afferentnykh sistem zheludka krys.