title: [Lipoprotein profile determinants in children and adolescents from a lipid consultation clinic. The impact of diet, body composition and physical activity].
abstract: OBJECTIVE
  Diet, physical activity, physical fitness and body composition are factors that contribute to lipid disorders; however, we do not know whether they are relevant in children of the general population and in children with dyslipoproteinemias.
  
  
  METHODS
  We have studied all of these factors in 89 children, aged 4.0 to 20.0 years. Children were divided into two groups: 1) Normocholesterolemics (total cholesterol < 225 mg/dL) and 2) Hypercholesterolemics (total cholesterol > or = 225 mg/dL).
  
  
  RESULTS
  In normocholesterolemic children, the main determinants of total and low-density lipoprotein cholesterol were height and cholesterol intake, which explained both 50 and 32% of its variability, respectively. The main determinants of high density lipoprotein cholesterol were blood pressure after submaximal loading and fat mass, which explained 50% of the variability. In hypercholesterolemic children, fat and carbohydrate intake and physical activity explained more than 90% of the variability of total and low density lipoprotein cholesterol. Resting energy expenditure explained 40% of the variability of high density lipoprotein cholesterol.
  
  
  CONCLUSIONS
  In the treatment of children and adolescents with dyslipoproteinemias, we must emphasize not only dietary intake, but also physical activity. To increase high density lipoprotein cholesterol we must also improve physical fitness and decrease the amount of body fat mass.
authors.affiliation: Departamento de Pediatria, Hospital Clínico Universitario Lozano Blesa, Zaragoza.
authors.forename: A
authors.initials: A
authors.lastname: Sarría Chueca
authors.forename: M T
authors.initials: MT
authors.lastname: Martín Nasarre de Letosa
authors.forename: B
authors.initials: B
authors.lastname: Lomba García
authors.forename: L A
authors.initials: LA
authors.lastname: Moreno Aznar
authors.forename: A
authors.initials: A
authors.lastname: Lázaro Almarza
authors.forename: M
authors.initials: M
authors.lastname: Bueno Sánchez
mesh_terms: D000293:Adolescent; D000328:Adult; D001823:Body Composition; D002648:Child; D002664:Child Nutritional Physiological Phenomena; D002675:Child, Preschool; D008076:Cholesterol, HDL / Q000097:blood*; D015243:Cholesterol, VLDL / Q000097:blood*; D004032:Diet; D015444:Exercise; D005260:Female; D006801:Humans; D006937:Hypercholesterolemia / Q000097:blood*; D008297:Male; D012189:Retrospective Studies
chemical_list: D008076:Cholesterol, HDL; D015243:Cholesterol, VLDL
vernacular_title: Determinantes del perfil lipídico en niños y adolescentes asistidos en una consulta de lípidos. Importancia de la dieta, composición corporal y actividad física.