title: The relationship between prevalence of Schistosoma haematobium infection and different morbidity indicators during the course of a control programme on Pemba Island.
abstract: A long-term schistosomiasis control programme was initiated on Pemba Island, Tanzania in 1986 with the aim of eliminating morbidity due to Schistosoma haematobium infection. The programme used haematuria as a community indicator of morbidity for surveillance and for identifying individuals for selective population chemotherapy. Analysis of the first 3 evaluation studies showed that the prevalence of microhaematuria was linearly related to the prevalence of infection, and that visually detectable haematuria was a marker of the intensity of infection and risk of morbidity in a community. These relationships remained consistent during repeated community-based chemotherapy, suggesting that measures of haematuria may be useful tools for surveillance.
authors.affiliation: Wellcome Trust Research Centre for Parasitic Infections, Imperial College of Science, Technology and Medicine, London, UK.
authors.forename: N J
authors.initials: NJ
authors.lastname: Lwambo
authors.forename: L
authors.initials: L
authors.lastname: Savioli
authors.forename: U M
authors.initials: UM
authors.lastname: Kisumku
authors.forename: K S
authors.initials: KS
authors.lastname: Alawi
authors.forename: D A
authors.initials: DA
authors.lastname: Bundy
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000980:Antiplatyhelmintic Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D006417:Hematuria / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D008875:Middle Aged; D011223:Praziquantel / Q000627:therapeutic use; D015995:Prevalence; D012044:Regression Analysis; D012553:Schistosomiasis haematobia / Q000188:drug therapy / Q000453:epidemiology* / Q000652:urine; D013636:Tanzania / Q000453:epidemiology
chemical_list: D000980:Antiplatyhelmintic Agents; D011223:Praziquantel