Sarcomatoid renal cell carcinoma: case report and review of the literature.
Sarcomatoid renal cell carcinoma (SRCC) is an uncommon tumor of the renal parenchyma, representing one to five percent of all primary kidney tumors. The major symptoms are the same as in the classic renal cell carcinoma: haematuria and flank pain. The tumor consists of a bimorph feature of clear cells with areas of spindle cells and giant cells, resembling a sarcoma. Immunohistochemistry and electronmicroscopy are often necessary to prove the epithelial origin of these spindle cells. Therapy is essentially surgical but in some cases there can be a benefit of chemotherapy.
Staelens
L
L
Department of Urology, University Hospitals, K.U. Leuven, Belgium.
Van Poppel
H
H
Vanuytsel
L
L
Van Oosterom
A
A
Van Damme
B
B
Baert
L
L
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002292:Carcinoma, Renal Cell / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary / Q000601:surgery; D019070:Cell Lineage; D004847:Epithelial Cells / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D015726:Giant Cells / Q000473:pathology; D006417:Hematuria / Q000175:diagnosis; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D008197:Lymph Node Excision; D008297:Male; D008854:Microscopy, Electron; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009392:Nephrectomy; D010146:Pain / Q000175:diagnosis; D010166:Palliative Care; D012509:Sarcoma / Q000473:pathology