[Trochlear paralysis within the scope of acute herpes hominis virus (HHV) 6 subtype B infection].
METHODS
A 33-year-old woman developed progressive trochlear palsy without further neurological disorders. HHV-6 subtype B viremia was found in serological examination.


METHODS
To prevent necrotizing encephalitis, a dangerous complication of untreated symptomatic acute HHV 6 subtype B infection, intravenous antiviral treatment consisting of initially ganciclovir, then ganciclovir and foscarnet in alternating combination and finally solitary foscarnet was performed. The result was complete eradication of viremia and restitution of the palsy.


CONCLUSIONS
Bearing the risk of necrotizing encephalitis, acute HHV-6 subtype B infection should be taken into consideration as a possible cause for progressive neuroophthalmological disturbances of unknown etiology.
Thierfelder
S
S
Universitäts-Augenklinik Würzburg.
Pfennigsdorf
S
S
Grehn
F
F
D000998:Antiviral Agents / Q000627:therapeutic use; D003389:Cranial Nerve Diseases / Q000175:diagnosis* / Q000188:drug therapy; D004359:Drug Therapy, Combination; D005260:Female; D006566:Herpesviridae Infections / Q000175:diagnosis* / Q000188:drug therapy; D015654:Herpesvirus 6, Human; D006801:Humans; D009886:Ophthalmoplegia / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome; D014321:Trochlear Nerve; D019562:Viral Load
D000998:Antiviral Agents
Trochlearisparese im Rahmen einer akuten Herpeshominis-Virus-(HHV)-6-Subtyp-B-Infektion.