[The pathogenetic and clinical significance of disorders in hemostatic homeostasis in diabetics].
DM patients who do not present with clinical manifestations of nephropathy exhibited significant reduction of urine fibrinolytic activity which is regarded as suggesting a preclinical stage of renal lesion in DM as well as hyperaggregation of platelets, enhanced activity of coagulative link of hemostasis and changes of different directions in the system of fibrinolysis. Among coagulologic methods, of most informative value is the turbidimetric method. In DM and low tolerability to glucosa, there is an increased incidence of gastroduodenal abnormalities, ulcer disease included, which fact warrants a gastroenterologic evaluation to be done in this patient population prior to prescribing anticoagulants.
Lapchyns'ka
I I
II
Bielits'ka
H O
HO
Kovalenko
S O
SO
D000328:Adult; D001780:Blood Coagulation Tests; D003922:Diabetes Mellitus, Type 1 / Q000097:blood* / Q000150:complications; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications; D003925:Diabetic Angiopathies / Q000097:blood / Q000209:etiology; D003928:Diabetic Nephropathies / Q000097:blood / Q000209:etiology; D005260:Female; D005951:Glucose Tolerance Test; D006487:Hemostasis; D006706:Homeostasis; D006801:Humans; D008297:Male; D008875:Middle Aged
Patohenetychne ta klinichne znachennia porushen' hemostatychnoho homeostazu u khvorykh na tsukrovyĭ diabet.