title: Recent advances in stroke therapy.
abstract: Advances in stroke therapy have followed diverse paths over the past 2 years. Recent clinical trials have investigated the use of thrombolytic agents, anticoagulants, antiplatelet drugs and neuroprotective agents in acute stroke patients. The positive results of the National Institutes of Neurologic Disease and Stroke tissue plasminogen activator trial have increased interest in the field of acute stroke therapy and initiated significant changes in the management of stroke patients in the medical system. A new antiplatelet drug and a number of trials involving HMG Co-A reductase inhibitors are important advances in the secondary prevention of stroke.
authors.affiliation: Department of Medicine, Sinai Hospital of Baltimore, Johns Hopkins University School of Medicine, Maryland, USA.
authors.forename: A
authors.initials: A
authors.lastname: Goldszmidt
authors.forename: R J
authors.initials: RJ
authors.lastname: Wityk
mesh_terms: D000208:Acute Disease; D000818:Animals; D002561:Cerebrovascular Disorders / Q000188:drug therapy* / Q000503:physiopathology; D005343:Fibrinolytic Agents / Q000627:therapeutic use*; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*
chemical_list: D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors