title: Ketamine for bone marrow aspiration and trephine biopsy in children.
abstract: To make bone marrow aspiration and trephine biopsy less painful and more acceptable in children a short acting anaesthetic ketamine was used in a dose of 1-2 mg/kg body weight intravenously or 4-5 mg/kg intramuscularly. One hundred cases aged 2 to 13 years were studied. The actual procedure time ranged between 20 seconds and 3 minutes, adequate samples were obtained in 80% of children on first attempt. Vomiting was the only side effect noted in two children. Ketamine is safe and recommended in all children undergoing bone marrow aspiration and trephine biopsies.
authors.affiliation: Department of Haematology, Armed Forces Institute of Pathology, CMH, Rawalpindi.
authors.forename: T
authors.initials: T
authors.lastname: Zafar
authors.forename: S
authors.initials: S
authors.lastname: Javaid
authors.forename: M
authors.initials: M
authors.lastname: Saleem
authors.forename: Z A
authors.initials: ZA
authors.lastname: Malik
authors.forename: M F
authors.initials: MF
authors.lastname: Khattak
mesh_terms: D000293:Adolescent; D000778:Anesthetics, Dissociative; D001706:Biopsy / Q000379:methods; D001856:Bone Marrow Examination / Q000379:methods*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D007649:Ketamine; D008297:Male
chemical_list: D000778:Anesthetics, Dissociative; D007649:Ketamine