Minimal inhibitory concentrations and minimal bactericidal concentrations of quinupristin/dalfopristin against clinical isolates of Corynebacterium jeikeium and Listeria monocytogenes.
Thirty clinical isolates of Listeria monocytogenes and 30 clinical isolates of Corynebacterium jeikeium were tested against quinupristin/dalfopristin by the NCCLS broth macrodilution technique for determination of MICs. MBC testing was also performed on the 60 isolates. Quinupristin/dalfopristin MIC90 values against L. monocytogenes and C. jeikeium were 1.6 mg/L and 0.2 mg/L, respectively. Quinupristin/dalfopristin was bacteriostatic against these organisms.
Moore
L S
LS
Medical Center of Delaware, Infectious Disease Research Laboratory, Wilmington 19899, USA.
Schneider
B
B
Holloway
W J
WJ
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003352:Corynebacterium / Q000187:drug effects*; D006801:Humans; D008089:Listeria monocytogenes / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D014769:Virginiamycin / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D014769:Virginiamycin; C062940:quinupristin-dalfopristin