Late onset Epstein-Barr virus-associated lymphoproliferative disease after allogeneic bone marrow transplant presenting as breast masses.
We report a patient who developed breast masses 17 months after a T cell-depleted partially mismatched related donor (PMRD) bone marrow transplant (BMT) for chronic myeloid leukemia. The patient had severe chronic graft-versus-host disease (GVHD) and the masses were due to Epstein-Barr virus (EBV) lymphoproliferative disease (LPD). The patient expired from fungal pneumonia after chemotherapy for the EBV-LPD.
Abhyankar
S H
SH
Department of Medicine, University of South Carolina and Richland Memorial Hospital, Columbia 29203, USA.
Chiang
K Y
KY
McGuirk
J P
JP
Pati
A R
AR
Godder
K T
KT
Welsh
J A
JA
Waldron
R L
RL
McElveen
J L
JL
Henslee-Downey
P J
PJ
D000328:Adult; D001228:Aspergillosis / Q000209:etiology / Q000401:mortality; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D001940:Breast / Q000473:pathology*; D002051:Burkitt Lymphoma / Q000209:etiology* / Q000473:pathology; D005260:Female; D006086:Graft vs Host Disease / Q000150:complications; D004854:Herpesvirus 4, Human; D006650:Histocompatibility Testing; D006801:Humans; D008172:Lung Diseases, Fungal / Q000209:etiology / Q000401:mortality; D014184:Transplantation, Homologous