title: Early fetal blood sampling--another available option for early prenatal diagnosis.
abstract: Fourteen cases had early fetal blood sampling (FBS) performed between 13 and 18 weeks gestation in the Antenatal Diagnostic Centre, National University Hospital, Singapore from Jan 1988 to December 1994. The indications were: a) ultrasound abnormality (n = 6), b) hydrops (n = 1), c) screening for blood disorders (n = 2), d) amnio results inconclusive or to confirm abnormal amnio results (n = 5). This article analyses retrospectively the early FBS procedure and its outcome. There were no procedure related fetal losses in this study. The reliable rapid results obtained following the procedure enabled the obstetrician to counsel the couple regarding the current pregnancy and advise them accordingly for the subsequent pregnancy. Thus we found it useful not only in our patients but also for patients from overseas who get their results within a week to plan their stay.
authors.affiliation: Department of Obstetrics and Gynecology, National University Hospital, Singapore, Rep. of Singapore.
authors.forename: C
authors.initials: C
authors.lastname: Anandakumar
authors.forename: V
authors.initials: V
authors.lastname: Annapoorna
authors.forename: Y C
authors.initials: YC
authors.lastname: Wong
authors.forename: D
authors.initials: D
authors.lastname: Chia
authors.forename: B
authors.initials: B
authors.lastname: Ariff
authors.forename: S S
authors.initials: SS
authors.lastname: Ratnam
mesh_terms: D001800:Blood Specimen Collection / Q000379:methods*; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D005260:Female; D005312:Fetal Blood; D005865:Gestational Age; D006801:Humans; D007621:Karyotyping; D008214:Lymphocytes / Q000648:ultrastructure; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods*; D016216:Ultrasonography, Prenatal