title: [Familial hypercholesterolemia: involvement of cerebral major arteries (communication 1)].
abstract: Ultrasound dopplerography, MR tomography were performed to assess the brain, major cerebral arteries and audiometry was conducted to study cochleovestibular system in 38 patients aged 16-63 years with heterozygous family hypercholesterolemia. Vascular disorders and defects in the white brain matter (in patients with transitory hypertension) were registered. Complications of cerebral atherosclerosis (brain infarction, perception cochleovestibular alterations) contributed to aggravation of ischemic heart disease. Patients with heterozygous family hypercholesterolemia should be observed and treated by cardiologist, neuropathologist and psychoneurologist to prevent cardiocerebral complications.
authors.forename: Kh G
authors.initials: KhG
authors.lastname: Alidzhanova
authors.forename: N N
authors.initials: NN
authors.lastname: Abramova
authors.forename: T V
authors.initials: TV
authors.lastname: Balakhonova
authors.forename: N E
authors.initials: NE
authors.lastname: Shevtsova
authors.forename: T P
authors.initials: TP
authors.lastname: Bessarab
authors.forename: V V
authors.initials: VV
authors.lastname: Kukharchuk
mesh_terms: D000293:Adolescent; D000328:Adult; D001783:Blood Flow Velocity; D001921:Brain / Q000098:blood supply / Q000473:pathology; D002533:Cerebral Angiography; D002536:Cerebral Arteries / Q000000981:diagnostic imaging / Q000473:pathology; D002561:Cerebrovascular Disorders / Q000150:complications* / Q000175:diagnosis / Q000503:physiopathology; D002784:Cholesterol / Q000097:blood; D005260:Female; D006579:Heterozygote; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000150:complications; D014280:Triglycerides / Q000097:blood; D018608:Ultrasonography, Doppler
chemical_list: D014280:Triglycerides; D002784:Cholesterol
vernacular_title: Semeĭnaia giperkholesterinemiia: porazhenie magistral'nykh arteriĭ golovnogo mozga.