title: Recent advances in gestational trophoblastic disease.
abstract: Important advances continue to occur in both our understanding and management of gestational trophoblastic disease. Complete molar pregnancy is being diagnosed earlier in pregnancy which affects its clinical and pathological presentation. The use of chemotherapy in persistent gestational trophoblastic tumors continues to be refined and our understanding of the immunobiology of these tumors has substantially advanced.
authors.affiliation: Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, MA 02115, USA.
authors.forename: R S
authors.initials: RS
authors.lastname: Berkowitz
authors.forename: D P
authors.initials: DP
authors.lastname: Goldstein
mesh_terms: D000951:Antigens, Neoplasm / Q000096:biosynthesis / Q000276:immunology; D000970:Antineoplastic Agents / Q000627:therapeutic use; D016207:Cytokines / Q000096:biosynthesis; D005260:Female; D005865:Gestational Age; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D008214:Lymphocytes / Q000276:immunology / Q000378:metabolism; D008264:Macrophages / Q000276:immunology / Q000378:metabolism; D011247:Pregnancy; D011379:Prognosis; D014328:Trophoblastic Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology; D014594:Uterine Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology
chemical_list: D000951:Antigens, Neoplasm; D000970:Antineoplastic Agents; D016207:Cytokines