[Are the anatomopathological classifications of primary Gougerot-Sjögren syndrome correlated with each-other and with clinical symptoms?].
Seventy-two cases of primary Sjögren's syndrome, according to the European classification criteria, were studied looking for a correlation between anatomic criteria and clinico-biological signs in this disease. Labial salivary gland biopsy was performed in all patients and anatomic criteria were evaluated according to both Chisholm and Chomette scales. Work-up included recording of functional and clinical signs. Our study shows no clinico-histological correlation in Sjögren's syndrome. Moreover, we did not find any correlation between the two histological scales. We think, therefore, that labial salivary gland biopsy appears to be an important step in Sjögren's syndrome diagnosis according to European criteria. However, it does not present any benefit in patient treatment.
Paccalin
M
M
Service de médecine interne, centre hospitalier universitaire La Milétrie, Poitiers.
Roblot
P
P
Goujon
J M
JM
Ramassamy
A
A
Debiais
F
F
Delaire
L
L
Vidal
E
E
Becq-Giraudon
B
B
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012470:Salivary Glands, Minor / Q000473:pathology; D012680:Sensitivity and Specificity; D012859:Sjogren's Syndrome / Q000145:classification / Q000473:pathology* / Q000503:physiopathology
Les classifications anatomopathologiques du syndrome de Gougerot-Sjögren primitif sont-elles corrélées entre elles et à la clinique?