[Efficacy of the lithium compound with prolonged action during "reserpine depression"].
A single administration of the new lithium compound with prolonged action formed on the basis of lithium oxyburate produces an antiblepharoptosis effect in rats with reserpine depression for 24 to 48 h. It optimally prevents the development of "reserpine-desynchronization" in rats when prescribed in the morning at intervals of 48 h.
Zamoshchina
T A
TA
Siberian State Medical University, Tomsk, Russia.
Saratikov
A S
AS
D000818:Animals; D000928:Antidepressive Agents / Q000494:pharmacology*; D001763:Blepharoptosis / Q000139:chemically induced / Q000517:prevention & control; D001831:Body Temperature / Q000187:drug effects; D002940:Circadian Rhythm; D003692:Delayed-Action Preparations; D003863:Depression / Q000139:chemically induced / Q000503:physiopathology / Q000517:prevention & control*; D005106:Exploratory Behavior / Q000187:drug effects; D006885:Hydroxybutyrates / Q000494:pharmacology*; D016651:Lithium Carbonate / Q000494:pharmacology; D008297:Male; D009942:Organometallic Compounds / Q000494:pharmacology*; D051381:Rats
D000928:Antidepressive Agents; D003692:Delayed-Action Preparations; D006885:Hydroxybutyrates; D009942:Organometallic Compounds; D016651:Lithium Carbonate; C022826:lithium hydroxybutyrate
Effektivnost' soedineniĭ litiia s prolongirovannym deĭstviem pri "rezerpinovoĭ depressii".