[Favism. Acute hemolysis after intake of fava beans].
Acute haemolysis due to Glucose-6-Phosphate-Dehydrogenase deficiency is a common disorder in American and African Blacks, in Mediterranean people and among Orientals. The erythrocytes in affected individuals have insufficient reducing power against toxic peroxydes and free radicals generated during metabolism. Normally, affected individuals are without signs of disease, but under the influence of oxydants severe intravascular haemolysis may occur. One of the most important oxydants is the fava bean which, when ingested, may cause acute favism, a condition which has a 10% mortality if not treated properly. We describe a 35 year-old man from Iraq who developed serious haemolytic anemia with a fall in haemoglobin to 6.5 g/100 ml three days after ingestion of fava beans. He was treated with intravenous fluids and blood transfusions. He recovered and was discharged from hospital after nine days. This is the first described case of favism in Norway.
Holm
B
B
Medisinsk avdeling, Lovisenberg Diakonale Sykehus, Oslo.
Jensenius
M
M
D000328:Adult; D005236:Favism / Q000175:diagnosis / Q000628:therapy; D006801:Humans; D007493:Iraq / Q000208:ethnology; D008297:Male; D009664:Norway
Favisme. Akutt hemolyse etter inntak av favabønner.