title: Patterns of gene duplication in lepidopteran pheromone binding proteins.
abstract: We have isolated and characterized cDNAs representing two distinct pheromone binding proteins (PBPs) from the gypsy moth, Lymantria dispar. We use the L. dispar protein sequences, along with other published lepidopteran PBPs, to investigate the evolutionary relationships among genes within the PBP multigene family. Our analyses suggest that the presence of two distinct PBPs in genera representing separate moth superfamilies is the result of relatively recent, independent, gene duplication events rather than a single, ancient, duplication. We discuss this result with respect to the biochemical diversification of moth PBPs.
authors.affiliation: Department of Biological Sciences, University of South Carolina, Columbia 29208, USA. merritt@biol.scarolina.edu
authors.forename: T J
authors.initials: TJ
authors.lastname: Merritt
authors.forename: S
authors.initials: S
authors.lastname: LaForest
authors.forename: G D
authors.initials: GD
authors.lastname: Prestwich
authors.forename: J M
authors.initials: JM
authors.lastname: Quattro
authors.forename: R G
authors.initials: RG
authors.lastname: Vogt
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002352:Carrier Proteins / Q000737:chemistry / Q000235:genetics*; D003001:Cloning, Molecular; D019476:Insect Proteins / Q000737:chemistry / Q000235:genetics*; D036341:Intercellular Signaling Peptides and Proteins; D007915:Lepidoptera / Q000235:genetics* / Q000378:metabolism; D008969:Molecular Sequence Data; D005810:Multigene Family; D010802:Phylogeny; D017386:Sequence Homology, Amino Acid
chemical_list: D002352:Carrier Proteins; D019476:Insect Proteins; D036341:Intercellular Signaling Peptides and Proteins; C111001:PBP1 protein, Lymantria dispar; C111000:PBP2 protein, Lymantria dispar