Myocardial rest iodine-123-beta-methyl-iodophenyl-pentadecanoic acid scintigraphy compared with dipyridamole stress thallium-201 scintigraphy in unstable angina.
Twelve patients with stable angina and 12 patients with unstable angina underwent rest iodine-123-beta-methyl-iodophenyl-pentadecanoic acid (BMIPP), dipyridamole stress thallium scintigraphy and delayed thallium scintigraphy. In stable angina, sensitivity for detecting ischemic segments was higher in dipyridamole thallium (74%) than rest BMIPP (48%) images (p<0.05), but there was no significant difference between the 2 images in unstable angina. In unstable angina, the incidence of segments with higher defect scores on BMIPP images than on delayed thallium images and the opposite pattern was 27 and 5 (p<0.01). In stable angina, there was no difference. The mean defect score on BMIPP (6.3 +/- 5.6) was higher than that on delayed thallium scintigraphy (2.9 +/- 2.7) and it was almost the same as on the initial dipyridamole stress test (6.5 +/- 5.2). In conclusion, BMIPP scintigraphy is safer and may be as useful in detecting myocardial ischemia in patients with unstable angina as thallium scintigraphy.
Misumi
I
I
Department of Cardiology, Kumamoto City Hospital, Kotoh, Kumamoto.
Kimura
Y
Y
Hokamura
Y
Y
Yamabe
H
H
Ueno
K
K
D000787:Angina Pectoris / Q000000981:diagnostic imaging; D000789:Angina, Unstable / Q000000981:diagnostic imaging*; D004176:Dipyridamole; D005227:Fatty Acids; D006801:Humans; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D011877:Radionuclide Imaging; D012146:Rest; D012680:Sensitivity and Specificity; D013312:Stress, Physiological; D013794:Thallium Radioisotopes
D005227:Fatty Acids; D007457:Iodine Radioisotopes; D007462:Iodobenzenes; D013794:Thallium Radioisotopes; C049338:iodofiltic acid; D004176:Dipyridamole