Gradient- and sensitivity-enhanced TOCSY experiments.
A pulsed field gradient version of the sensitivity-enhanced 2D TOCSY experiment is proposed which yields high-quality spectra with improved sensitivity and a minimum of two scans per t1 increment. For rapid acquisition of 1D TOCSY spectra, the 1D DPFGSE-TOCSY experiment was modified to include phase-encoded multiple-selective excitation followed by a simple spectral editing. Combination of these two building blocks is used in a sensitivity-enhanced 2D analog of the 3D TOCSY-TOCSY experiment which provides an efficient tool for resolving severely overlapped signals of oligomers in short experimental time.
Kövér
K E
KE
Department of Organic Chemistry, L. Kossuth University, Debrecen, H-4010, Hungary.
Uhrín
D
D
Hruby
V J
VJ
D000701:Analgesics, Opioid / Q000737:chemistry; D016477:Artifacts; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D009682:Magnetic Resonance Spectroscopy; D009842:Oligopeptides / Q000737:chemistry; D012680:Sensitivity and Specificity; D012984:Software
D000701:Analgesics, Opioid; D009842:Oligopeptides; C060208:deltorphin I, Ala(2)-