title: Algorithmic analysis of in vitro chemotherapy against Pneumocystis carinii.
abstract: The development of in vitro experimental chemotherapy against P.carinii has been hindered by the lack of efficient methods for continuous cultivation of the microorganism. Various short-term systems, allowing the production of infectious forms of Pneumocystis, can be employed for in vitro experimental chemotherapy. The purpose of the present study is to describe a statistically relevant algorithmic model for the evaluation of P.carinii in short-term in vitro culture and drug screening.
authors.affiliation: II Div. Inf. Dis., L. Sacco Hosp. Milan, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Atzori
authors.forename: F
authors.initials: F
authors.lastname: Agostoni
authors.forename: E
authors.initials: E
authors.lastname: Angeli
authors.forename: A
authors.initials: A
authors.lastname: Cargnel
authors.forename: L
authors.initials: L
authors.lastname: Drago
authors.forename: M R
authors.initials: MR
authors.lastname: Gismondo
mesh_terms: D000465:Algorithms; D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D002460:Cell Line; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D011010:Pneumocystis / Q000187:drug effects*; D051381:Rats
chemical_list: D000935:Antifungal Agents