Synthesis of novel mammalian metabolites of the isoflavonoid phytoestrogens daidzein and genistein.
The synthesis of novel mammalian metabolites of dietary isoflavones, dihydrodaidzein (4',7-dihydroxyisoflavanone) 7, dihydrogenistein (4',5,7-trihydroxyisoflavanone) 9, 6'-hydroxy-O-demethylangolensin [1-(2,4,6-trihydroxyphenyl)-2-(4-hydroxyphenyl)propan-1-one] 10, and cis- and trans-4',7-dihydroxyisoflavan-4-ols 11, 12 is described, and their characteristics by physical and chemical constants given for the first time.
Wähälä
K
K
Department of Chemistry, University of Helsinki, Finland. Kristiina.Wahala@helsinki.fi
Salakka
A
A
Adlercreutz
H
H
D019833:Genistein / Q000378:metabolism*; D006801:Humans; D007529:Isoflavones / Q000378:metabolism*
D007529:Isoflavones; C004742:daidzein; D019833:Genistein