Effects of posterior chamber lens implantation on the endothelium of transplanted corneas.
OBJECTIVE
The morphological changes of the corneal endothelium after posterior chamber lens implantation in the transplanted corneas were investigated.


METHODS
36 patients underwent extracapsular cataract extraction with posterior chamber lens implantation. Among these, penetrating keratoplasty had been performed in 18 patients before cataract surgery. The indications for penetrating keratoplasty in these cases included keratoconus, herpetic keratitis, and macula cornea. 18 cataract patients with normal corneas were also studied as controls. The central corneal endothelium in each subject was examined with a wide field specular microscope at a few days before and 3 months after cataract surgery.


RESULTS
Although the transplanted corneas showed lower endothelial cell densities, marked polymegethism, and pleomorphism in the baseline variables, the endothelial morphological changes in the transplanted corneas after posterior chamber lens implantation were comparable with those in the normal corneas. Also, there was no clinical evidence, especially, of corneal epithelial and/or endothelial rejections and corneal decompensation in all corneas.


CONCLUSIONS
Even though the transplanted corneas have a lower endothelial cell density and marked polymegethism, it is believed that cataract surgery does not induce corneal decompensation in cases where the peripheral recipient endothelium can be considered to have normal morphology.
Ohguro
N
N
Department of Ophthalmology, Osaka University Medical School, Japan.
Matsuda
M
M
Kinoshita
S
S
D000328:Adult; D000368:Aged; D002387:Cataract Extraction; D002452:Cell Count; D004728:Endothelium, Corneal / Q000473:pathology*; D005500:Follow-Up Studies; D006801:Humans; D015948:Keratoplasty, Penetrating / Q000473:pathology*; D019654:Lens Implantation, Intraocular; D008875:Middle Aged; D011184:Postoperative Period