title: Primary leptomeningeal astrocytoma. Case report.
abstract: Gliomas very rarely arise from the leptomeninges. They can be both solitary and diffuse, and histological examination reveals mostly astrocytic tumors. The authors report a case (the 12th reported in the literature) of a solitary primary glioma of the leptomeninges in a 79-year-old man who presented with repeated seizures. A magnetic resonance image revealed an ill-defined enhancing lesion in the cerebral meninges. Autopsy examination showed a poorly demarcated astrocytoma in the sylvian fissure infiltrating the adjacent subarachnoid space. The literature concerning primary leptomeningeal glioma is reviewed.
authors.affiliation: Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong.
authors.forename: H K
authors.initials: HK
authors.lastname: Ng
authors.forename: W S
authors.initials: WS
authors.lastname: Poon
mesh_terms: D000368:Aged; D001099:Arachnoid / Q000473:pathology*; D001254:Astrocytoma / Q000175:diagnosis* / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D009361:Neoplasm Invasiveness; D010296:Parietal Lobe / Q000473:pathology; D010841:Pia Mater / Q000473:pathology*; D012640:Seizures / Q000175:diagnosis; D013346:Subarachnoid Space; D013702:Temporal Lobe / Q000473:pathology