[Evaluation of risk factors for endometrial adenocarcinoma in women with diabetes, hypertension and obesity hospitalized for pathologic uterine hemorrhage around the age of postmenopause].
The aim of the study was to investigate the incidence and risk factors for endometrial adenocarcinoma which are associated with abnormal bleeding patterns, overweight, a lower number of deliveries and a later menopause, diabetes mellitus and hypertension. A retrospective study (from 1991 to 1993) of 2887 women with pathological gynecological sings and symptoms was performed. Risk factors such as age, height, weight, Brock index, age of menopause, diabetes mellitus and hypertension, stage and cell type were analyzed. The patients were between 38 to 35 years old (average 53.9 +/- 10.2). They were divided into two subgroups: 259 patients below 85 years of age with a histologically confirmed neoplasm, and 2628 women hospitalised due to gynecological signs and symptoms which were not, however, diagnosed as neoplastic disorders. However, it is necessary to note the relationship between the typical age for these two characteristics and the typical age for endometrial cancer. Diabetes was found to be a strong factor whereas hypertension appears to be a relatively weak one for endometrial carcinoma. High Brock's index is also associated with ab increased risk of endometrial carcinoma.
Friebe
Z
Z
Kliniki Ginekologii, Połoznictwa Akademii Medycznej, Poznaniu.
Bembnista
M
M
Nowakowski
B
B
D000230:Adenocarcinoma / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003920:Diabetes Mellitus / Q000209:etiology*; D016889:Endometrial Neoplasms / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D006973:Hypertension / Q000209:etiology*; D008593:Menopause; D008875:Middle Aged; D009765:Obesity / Q000150:complications*; D011044:Poland; D012189:Retrospective Studies; D012307:Risk Factors; D014592:Uterine Hemorrhage / Q000209:etiology*
Ocena ryzyka powstania raka błony śluzowej macicy u kobiet z cukrzyca, nadciśnieniem i otyłościa, hospitalizowanych z powodu patologicznych krwawień z macicy, w wieku około-i pomenopauzalnym.