Localized squamous cell carcinoma of the bladder causing hypercalcemia and inhibition of PTH secretion.
We report a case of symptomatic hypercalcemia in a patient with muscle-invasive, resectable squamous cell carcinoma of the bladder. Serum parathyroid hormone was consistent with secretion of parathyroid hormone-related protein. After radical cystoprostatectomy, calcium levels returned to normal. Patients with squamous cell carcinoma and an abnormal serum calcium level may have localized disease and should not be denied definitive local therapy.
Wolchok
J D
JD
Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Herr
H W
HW
Kelly
W K
WK
D002294:Carcinoma, Squamous Cell / Q000150:complications* / Q000378:metabolism; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology* / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000378:metabolism*; D001749:Urinary Bladder Neoplasms / Q000150:complications* / Q000378:metabolism
D010281:Parathyroid Hormone