title: Intermediate filaments and their associated proteins: multiple dynamic personalities.
abstract: A fusion of mouse and human genetics has now proven that intermediate filaments form a flexible scaffold essential for structuring cytoplasm in a variety of cell contexts. In some cases, the formation of this scaffold is achieved through a newly identified family of intermediate-filament-associated proteins that form cross-bridges between intermediate filaments and other cytoskeletal elements, including actin and microtubules.
authors.affiliation: Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla 92093, USA.
authors.forename: M K
authors.initials: MK
authors.lastname: Houseweart
authors.forename: D W
authors.initials: DW
authors.lastname: Cleveland
mesh_terms: D000818:Animals; D006801:Humans; D007381:Intermediate Filament Proteins / Q000502:physiology*; D007382:Intermediate Filaments / Q000502:physiology*; D051379:Mice
chemical_list: D007381:Intermediate Filament Proteins