title: Mycosis fungoides with focal segmental glomerular sclerosis and nephrotic syndrome.
abstract: Cutaneous T-cell lymphoma includes mycosis fungoides and the leukemic variant, Sézary syndrome. We report the first two cases of focal segmental glomerulosclerosis in patients with cutaneous T-cell lymphoma, with nephrotic range proteinuria and review the literature on renal disease coexisting with cutaneous T-cell lymphoma. We hypothesize that glomerular injury in cutaneous T-cell lymphoma may be related to interleukin-2.
authors.affiliation: Division of Medical Specialties, University of Texas Medical School, Houston, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Cather
authors.forename: C
authors.initials: C
authors.lastname: Jackow
authors.forename: J
authors.initials: J
authors.lastname: Yegge
authors.forename: F
authors.initials: F
authors.lastname: Hagemeister
authors.forename: M
authors.initials: M
authors.lastname: Duvic
mesh_terms: D001706:Biopsy; D003131:Combined Modality Therapy; D005923:Glomerulosclerosis, Focal Segmental / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007668:Kidney / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000175:diagnosis* / Q000628:therapy; D009404:Nephrotic Syndrome / Q000175:diagnosis* / Q000628:therapy; D011507:Proteinuria / Q000175:diagnosis / Q000628:therapy; D012535:Scalp / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000628:therapy