title: Gestational diabetes mellitus and glucose intolerance in a Mexican population.
abstract: OBJECTIVE
  To determine the prevalence of gestational diabetes mellitus (GDM), glucose intolerance (GI) and macrosomia in a Latin Mexican population, using the one-step procedure proposed by the World Health Organization.
  
  
  METHODS
  Consecutive pregnant women (n = 667) who attended the antenatal clinic and delivered at the hospital were recruited after 24 weeks of gestation, mean 34.2 weeks, range 24-40 weeks. After a minimum of 3 days with a 150-g carbohydrate diet, a glucose load of 75 g was administered and 2 h after, a blood sample for glucose was taken, plasma was separated and immediately processed for glucose, using a glucose-oxidase method.
  
  
  RESULTS
  Twenty women were diagnosed with GDM (3%), 87 had GI (13%) and 560 had a normal glucose response (84%). Macrosomia occurred in two (10%) of GDM, in nine (10.3%) of GI, and in 29 (5.4%) gravidas with a normal response, respectively. Only one of the macrosomic infants whose mother had GI, had neonatal hypoglycemia and hyperbilirubinemia.
  
  
  CONCLUSIONS
  The overall prevalence of glucose abnormalities during pregnancy was 16%. GI in this group was associated to macrosomia at the same rate as GDM.
authors.affiliation: Department of Endocrinology, Hospital de Gineco-Obstetricia Dr. I. Morones, Monterrey, Mexico.
authors.forename: G
authors.initials: G
authors.lastname: Forsbach
authors.forename: C
authors.initials: C
authors.lastname: Cantú-Diaz
authors.forename: J
authors.initials: J
authors.lastname: Vázquez-Lara
authors.forename: M A
authors.initials: MA
authors.lastname: Villanueva-Cuellar
authors.forename: C
authors.initials: C
authors.lastname: Alvarez y García
authors.forename: E
authors.initials: E
authors.lastname: Rodríguez-Ramírez
mesh_terms: D000328:Adult; D016640:Diabetes, Gestational / Q000453:epidemiology*; D005260:Female; D005320:Fetal Macrosomia / Q000453:epidemiology; D018149:Glucose Intolerance / Q000453:epidemiology*; D005951:Glucose Tolerance Test; D006801:Humans; D007231:Infant, Newborn; D008800:Mexico / Q000453:epidemiology; D011247:Pregnancy; D015995:Prevalence