Conservation of locus-specific microsatellite variability across species: a comparison of two Drosophila sibling species, D. melanogaster and D. simulans.
Fifteen microsatellite loci were studied in Drosophila melanogaster and Drosophila simulans, two closely related sibling species which split 2-3.5 MYA. Within-species variances in repeat number were found to differ up to 1,000-fold among individual microsatellite loci. A significant correlation of log variances between both species indicated a locus-specific mutation rate of microsatellites. Hence, locus-specific effects are apparently among the major forces influencing microsatellite variation and deserve more consideration in microsatellite analysis.
Harr
B
B
Institut für Tierzucht und Genetik, Veterinärmedizinische Universität Wien, Austria.
Zangerl
B
B
Brem
G
G
Schlötterer
C
C
D000349:Africa; D000818:Animals; D004330:Drosophila / Q000145:classification / Q000235:genetics*; D004331:Drosophila melanogaster / Q000145:classification / Q000235:genetics; D019143:Evolution, Molecular; D005819:Genetic Markers; D018895:Microsatellite Repeats; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D013045:Species Specificity
D005819:Genetic Markers