Severe muscle damage induced by high carbohydrate intake from elemental diet in a patient with Crohn's disease.
Crohn's disease is associated with complications in multiple organs. However, there are very few reported cases of patients with Crohn's disease with muscle symptoms and/or high serum creatine phospho-kinase (CPK) levels. We report here a patient with Crohn's disease who experienced skeletal muscle damage with extremely high serum CPK level during treatment with an elemental diet. The non-parenteral administration of large amounts of carbohydrate and limited glycogen degradation capability may be a possible causative mechanism for this elemental diet-induced muscle damage.
Waki
S
S
Department of Medicine, Kobe University School of Medicine, Japan.
Kawanami
C
C
Kanda
F
F
Uenoyama
Y
Y
Maekawa
T
T
Fukui
H
H
Okada
A
A
Matsushima
Y
Y
Kishi
K
K
Kinoshita
Y
Y
Chiba
T
T
D000328:Adult; D003402:Creatine Kinase / Q000097:blood; D003424:Crohn Disease / Q000150:complications* / Q000178:diet therapy* / Q000201:enzymology; D005260:Female; D005526:Food, Formulated / Q000009:adverse effects*; D006801:Humans; D018482:Muscle, Skeletal / Q000293:injuries* / Q000473:pathology*; D009748:Nutrition Disorders / Q000150:complications* / Q000201:enzymology
D003402:Creatine Kinase