[The optimization of the hemodynamic characteristics in patients with ischemic heart disease and circulatory failure by using a substrate-coenzyme complex].
On the basis of findings from evaluation of 65 patients with ischemic heart disease presenting with functional class II-III effort angina and FC II-III circulatory insufficiency (NYHA) a comparative assessment was carried out of efficacy of combined therapy involving basic antianginal agents and glucose-insulin-potassium mixture plus glutaminic acid versus solitary basic therapy. It has been shown that combined versus basic therapy is much more capable of restoring cardiohemodynamic interrelations. This was evidenced by a significant reduction of the postexercise level, improvement in the coordination of work of the arterial system, and augmentation of the left ventricular inotropic function.
Vizir
A D
AD
Dunaev
V V
VV
Berezin
A E
AE
Kraĭdashenko
O V
OV
D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000188:drug therapy / Q000503:physiopathology; D002317:Cardiovascular Agents / Q000627:therapeutic use*; D004338:Drug Combinations; D004359:Drug Therapy, Combination; D006333:Heart Failure / Q000188:drug therapy* / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000188:drug therapy* / Q000503:physiopathology; D005082:Physical Exertion
D002317:Cardiovascular Agents; D004338:Drug Combinations
Optimizatsiia gemodinamicheskikh kharakteristik u bol'nykh ishemicheskoĭ bolezn'iu serdtsa s nedostatochnost'iu krovoobrashcheniia s pomoshch'iu substratno-kofermentnogo kompleksa.