title: The 10 years single center experience of using elderly donors for living related kidney transplantation.
abstract: The use of elderly donors has been advocated to expand the organ donor pool because of increased needs and organ shortage. The aim of the study was to analyse whether old age of donors affects the outcome of renal transplantation and the long term safety of retrieval for the donors. We present data of 335 consecutive living related kidney transplants, performed in our centre the last 10 years, where in 174 patients the donor was less than 60 years of age, while in the rest 161 patients the donor was more than 60 years of age. No statistical difference was noted in either group at the incidence of irreversible acute rejections, early acute tubular necrosis, vascular complications and patient deaths. The graft survival was 86.7%, 80.4% and 78.1% for the 3rd, the 5th and the 8th year for the younger group of donors, while it was 83.6%, 78.2% and 67.8% for the older group (p = 0.13). Patient survival of the younger group was 95.9%, 94.7% and 94.7%, while for the older was 94.4%, 92.0% and 89.2% for the 3rd, the 5th, and the 8th year post transplantation (p = 0.24). Functional rehabilitation and quality of life were good in donors and recipients of both groups. These results suggest that renal transplantation from elderly donors offers comparable results from those obtained from younger donors.
authors.affiliation: Transplantation Centre, Laïkon General Hospital, Athens, Greece.
authors.forename: A
authors.initials: A
authors.lastname: Kostakis
authors.forename: J
authors.initials: J
authors.lastname: Bokos
authors.forename: D
authors.initials: D
authors.lastname: Stamatiades
authors.forename: G
authors.initials: G
authors.lastname: Zavos
authors.forename: J
authors.initials: J
authors.lastname: Boletis
authors.forename: J
authors.initials: J
authors.lastname: Papadogianakis
authors.forename: C
authors.initials: C
authors.lastname: Stathakis
authors.forename: G
authors.initials: G
authors.lastname: Skalkeas
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006085:Graft Survival; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D014019:Tissue Donors