[Effects of hemosorption and combined therapy on cerebral perfusion pressure in patients with severe craniocerebral trauma].
Hemoperfusion with local heparin before and protamine after the column was used in the treatment of patients with grave craniocerebral injury. Effect of such treatment on the cerebral perfusion pressure (CPP) is analyzed. The treatment did not increase the liquor pressure but decreased it by 20-25 mm H2O in both groups of patients. CPP in the survivors improved and normalized. In the other group (dead patients) CPP did not change, despite a decrease of the liquor pressure, and remained high. These values can be prognostically important.
Isaev
Iu V
IuV
Dhangirova
G M
GM
Bichurina
V A
VA
Asriiants
S Iu
SIu
Poliakh
V F
VF
Fedorova
V Iu
VIu
Shadrin
A G
AG
D000293:Adolescent; D000328:Adult; D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage*; D001930:Brain Injuries / Q000503:physiopathology / Q000628:therapy*; D002560:Cerebrovascular Circulation; D002648:Child; D002675:Child, Preschool; D005260:Female; D006464:Hemoperfusion; D006493:Heparin / Q000008:administration & dosage*; D006494:Heparin Antagonists / Q000008:administration & dosage*; D006801:Humans; D007427:Intracranial Pressure; D008875:Middle Aged; D011379:Prognosis; D011479:Protamines / Q000008:administration & dosage*
D000925:Anticoagulants; D006494:Heparin Antagonists; D011479:Protamines; D006493:Heparin
Vliianie gemosorbtsii v kompleksnoĭ terapii bol'nykh s tiazheloĭ cherepno-mozgovoĭ travmoĭ na tserebralnoe perfuzionnoe davlenie.