title: Pancreatic resection for periampullary cancer in elderly patients.
abstract: OBJECTIVE
  Major abdominal surgery in elderly patients has traditionally been thought to carry a high operative risk. Recent data, however, have suggested that with proper selection, elderly patients can withstand pancreatic resection.
  
  
  METHODS
  The medical records of 102 patients who underwent pancreatic resection for pancreatic or periampullary tumors were retrospectively reviewed. Twenty-nine patients were aged 70 years or older (mean age: 74 years) and 73 patients were younger (mean age: 56 years). Concomitant comorbid conditions were evaluated in the patients of both groups, and no significant differences were identified. A pancreaticoduodenectomy was performed in 81 cases and a total pancreatectomy in 21.
  
  
  RESULTS
  The operative mortality rate was 0% in the older patients and 6.8% in the younger patients. Major complications occurred in 28% of the patients. There were no significant differences in morbidity among the two age groups. The overall actuarial survival curves showed similar trends in both groups.
  
  
  CONCLUSIONS
  With appropriate preoperative selection, pancreatic resection can be performed with low operative risk in elderly patients. Chronological age alone should not be considered an absolute contraindication for pancreatic resection.
authors.affiliation: Department of Surgery, Catholic University of Rome, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Magistrelli
authors.forename: R
authors.initials: R
authors.lastname: Masetti
authors.forename: R
authors.initials: R
authors.lastname: Coppola
authors.forename: M E
authors.initials: ME
authors.lastname: Riccioni
authors.forename: A
authors.initials: A
authors.lastname: Crucitti
authors.forename: G
authors.initials: G
authors.lastname: Nuzzo
authors.forename: A
authors.initials: A
authors.lastname: Picciocchi
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008875:Middle Aged; D010180:Pancreatectomy / Q000009:adverse effects / Q000401:mortality; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000601:surgery*; D011183:Postoperative Complications; D012189:Retrospective Studies; D015996:Survival Rate