title: Experience with uni- (LVAD) and biventricular (ECMO) circulatory support in postcardiotomy pediatric patients.
abstract: In six pediatric patients with postoperative low-output-syndrome (LOS), uni-(LVAD) and biventricular (ECMO) assist systems with Biomedicus centrifugal pump were used. ECMO was applied in 5 children aged between 3 days and 16 years, one infant with an age of 16 months was implanted with LVAD. One patient from the ECMO-group and the patient with LVAD-support survived. Analysis of vital organ functions during ECMO and LVAD support are presented and characteristics of both support systems for use in pediatric patients with postcardiotomy LOS based on worldwide experience discussed. In conclusion, both, uni- (LVAD) and biventricular circulatory support (ECMO) using Biomedicus centrifugal pump can be safely applied for management of postcardiotomy LOS even in neonates, however, ECMO support in comparison to LVAD is a more aggressive approach associated with a higher complication rate.
authors.affiliation: Clinic of Heart Surgery, University of Cologne, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Borowski
authors.forename: H
authors.initials: H
authors.lastname: Korb
mesh_terms: D000293:Adolescent; D002303:Cardiac Output, Low / Q000209:etiology / Q000601:surgery*; D006348:Cardiac Surgical Procedures / Q000009:adverse effects*; D002675:Child, Preschool; D015199:Extracorporeal Membrane Oxygenation; D005260:Female; D006333:Heart Failure / Q000503:physiopathology; D006353:Heart-Assist Devices; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D017682:Myocardial Stunning / Q000517:prevention & control; D010976:Platelet Count; D016896:Treatment Outcome