title: [Structural changes in the collagen fibers of the connective tissue in chronic inflammation in the periodontium].
abstract: Data of examinations of the periodontium during chronic inflammations are analyzed. Immunohistochemical studies revealed that the connective-tissue cicatrix forming in the course of reparative regeneration of the periodontium is immature and incapable of performing mechanical functions. The authors suggest that the above regeneration abnormalities lead to a relapsing occlusion injury of the periodontium and progress of the inflammatory sclerotic process. Perspective trends of the patho- and morphogenetic research of chronic periodontitis are outlined, as are the probable theoretical approaches to development of methods for correction of such abnormalities.
authors.forename: D V
authors.initials: DV
authors.lastname: Bogomolov
authors.forename: B V
authors.initials: BV
authors.lastname: Shekhonin
authors.forename: A A
authors.initials: AA
authors.lastname: Chumakov
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002908:Chronic Disease; D003094:Collagen / Q000378:metabolism*; D003238:Connective Tissue / Q000378:metabolism* / Q000473:pathology; D005109:Extracellular Matrix / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D010518:Periodontitis / Q000378:metabolism* / Q000473:pathology; D010519:Periodontium / Q000378:metabolism / Q000473:pathology
chemical_list: D003094:Collagen
vernacular_title: Izmeneniia stroeniia kollagenovykh volokon soedinitel'noĭ tkani pri khronicheskom vospalenii v periodonte.