title: Ejaculatory stimulation, quality of semen and reproductive aspects in spinal cord injured men.
abstract: this is a retrospective study of 39 male spinal cord injured patients who, over the last 5 years, have consulted us for ejaculatory dysfunction or infertility. All of these patients underwent at least two distinct sessions during which attempts were made to induce an ejaculation by vibratory stimulation, electric stimulation, or by using subcutaneous physostigmine. A semen analysis was performed each time that an ejaculate was obtained. By one or more of these techniques, 75% of these subjects were able to ejaculate. The level of the neurological lesion had a significant influence on the success rate. Likewise, the mode employed to produce an ejaculation influenced certain characteristics of the sperm collected (mean volume, percentage of motile forms), the best results being obtained by vibratory stimulation. Among the 10 couples who had consulted us for medically assisted reproduction, three pregnancies were obtained, two of which resulted in the birth of healthy children. Although the techniques of stimulation that we use allow ejaculation, the possibilities of reproduction remain limited in particular because of the difficulty in obtaining semen of adequate quality. Nevertheless, recent methods of micromanipulation of gametes should considerably improve the prognosis of the seminal insufficiencies in men with spinal cord injury.
authors.affiliation: Neurorehabilitation Unit, Pellegrin University Hospital, Bordeaux, France.
authors.forename: L
authors.initials: L
authors.lastname: Le Chapelain
authors.forename: P
authors.initials: P
authors.lastname: Nguyen Van Tam
authors.forename: P
authors.initials: P
authors.lastname: Dehail
authors.forename: J J
authors.initials: JJ
authors.lastname: Berjon
authors.forename: M
authors.initials: M
authors.lastname: Barat
authors.forename: J M
authors.initials: JM
authors.lastname: Mazaux
authors.forename: P A
authors.initials: PA
authors.lastname: Joseph
mesh_terms: D000328:Adult; D002800:Cholinesterase Inhibitors; D004542:Ejaculation / Q000502:physiology*; D004558:Electric Stimulation; D006801:Humans; D008297:Male; D008875:Middle Aged; D010830:Physostigmine; D012098:Reproduction / Q000502:physiology; D012189:Retrospective Studies; D012661:Semen / Q000166:cytology / Q000502:physiology*; D013119:Spinal Cord Injuries / Q000503:physiopathology*; D014732:Vibration
chemical_list: D002800:Cholinesterase Inhibitors; D010830:Physostigmine