title: Do retrospective and prospective quality of life assessments differ for pancreas-kidney transplant recipients?
abstract: The literature indicates that chronically ill patients have a remarkable capacity to adapt to their illness. For example, they will generally report a better quality of life (QoL) than individuals in the general population who are asked to imagine themselves as chronically ill and to rate their QoL. The present study further explores this phenomenon in type I diabetic transplant recipients with end-stage renal disease. In a prospective, longitudinal study, we assessed the QoL in 22 patients, both before and after they received a combined pancreas-kidney transplant. After transplantation, the patients were also asked to assess their pretransplant QoL by rating it on a 10-point scale. What we found was that prior to transplantation, QoL was prospectively given a mean rating of 5.23; this score increased to 7 after a successful transplant procedure. During follow-up assessments 5, 12, and 18 months after successful transplantation, patients retrospectively scored their pretransplant QoL as 3.27, 3.14, and 3.05, respectively. We conclude that when type I diabetic patients with end-stage renal disease undergo a transplant procedure to improve their health status, they re-evaluate their pretransplant QoL, and this retrospective assessment is significantly lower than their prospective one when transplantation is successful.
authors.affiliation: Department of Health, Organisation, Policy and Economics (BEOZ), Faculty of Health Sciences, University of Maastricht, The Netherlands. Eddy.Adang@BEOZ.unimaas.nl
authors.forename: E M
authors.initials: EM
authors.lastname: Adang
authors.forename: G
authors.initials: G
authors.lastname: Kootstra
authors.forename: G L
authors.initials: GL
authors.lastname: Engel
authors.forename: J P
authors.initials: JP
authors.lastname: van Hooff
authors.forename: H L
authors.initials: HL
authors.lastname: Merckelbach
mesh_terms: D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D016030:Kidney Transplantation; D008137:Longitudinal Studies; D016035:Pancreas Transplantation; D017060:Patient Satisfaction; D011446:Prospective Studies; D011788:Quality of Life; D012189:Retrospective Studies; D018434:Sickness Impact Profile