title: Neuroleptic malignant syndrome in the acquired immunodeficiency syndrome.
abstract: Patients infected by the human immunodeficiency virus are predisposed to many infectious and noninfectious complications and often receive a variety of drugs. Furthermore, they seem to have a particular susceptibility to idiosyncratic adverse drug reactions. It is therefore surprising that only a few cases of the neuroleptic malignant syndrome have been described in patients with the acquired immunodeficiency syndrome. A high index of suspicion is required to diagnose the neuroleptic malignant syndrome in these patients, as its usual manifestations, including fever and altered consciousness, are frequently attributed to an underlying infection.
authors.affiliation: Department of Internal Medicine, Hospital Marqués de Valdecilla, University of Cantabria, Santander, Spain.
authors.forename: J L
authors.initials: JL
authors.lastname: Hernández
authors.forename: L
authors.initials: L
authors.lastname: Palacios-Araus
authors.forename: S
authors.initials: S
authors.lastname: Echevarría
authors.forename: A
authors.initials: A
authors.lastname: Herrán
authors.forename: J F
authors.initials: JF
authors.lastname: Campo
authors.forename: J A
authors.initials: JA
authors.lastname: Riancho
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009459:Neuroleptic Malignant Syndrome / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012307:Risk Factors
chemical_list: D014150:Antipsychotic Agents