title: Spontaneous splenic rupture in infectious mononucleosis: a review.
abstract: Spontaneous rupture of the spleen is a rare complication of infectious mononucleosis (IM) occurring in 0.1-0.5 percent of patients with proven IM [1]. Although splenectomy has been advocated as the definitive therapy in the past, numerous recent reports have documented favorable outcomes with non-operative management. A review of the literature suggests that non-operative management can be successful if appropriate criteria, such as hemodynamic stability and transfusion requirements are applied in patient selection. We report the case of a 36 year old man with infectious mononucleosis who had a spontaneous splenic rupture and who was successfully managed by splenectomy. Based on review of the literature, an approach to management of a spontaneously ruptured spleen secondary to IM is suggested.
authors.affiliation: Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA. Maryam.Asgari@yale.edu
authors.forename: M M
authors.initials: MM
authors.lastname: Asgari
authors.forename: D G
authors.initials: DG
authors.lastname: Begos
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications*; D008297:Male; D013156:Splenectomy / Q000009:adverse effects; D013161:Splenic Rupture / Q000473:pathology / Q000601:surgery* / Q000628:therapy*