Quinolinic acid: effect on the nucleus arcuatus of the hypothalamus in the rat (ultrastructural evidence).
Quinolinic acid was administered intraperitoneally to male Wistar rats in a dose of 60 mmol, once daily for 8 days. By electron microscopy, in quinolinic acid-treated rats, the neuronal cell bodies in the arcuate nucleus had features of increased cellular activity, but some damage of neuronal cell bodies was also evident.
Beskid
M
M
Medical Centre of Postgraduate Education, Laboratory of Histochemistry, Warsaw, Poland.
Rózycka
Z
Z
Taraszewska
A
A
D000818:Animals; D001111:Arcuate Nucleus of Hypothalamus / Q000187:drug effects* / Q000648:ultrastructure; D002467:Cell Nucleus / Q000187:drug effects / Q000648:ultrastructure; D003593:Cytoplasm / Q000187:drug effects / Q000648:ultrastructure; D003594:Cytoplasmic Granules / Q000187:drug effects / Q000648:ultrastructure; D007274:Injections, Intraperitoneal; D008297:Male; D008854:Microscopy, Electron; D009474:Neurons / Q000648:ultrastructure; D017378:Quinolinic Acid / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar
D017378:Quinolinic Acid