title: Selenium level and glutathione peroxidase activity in plasma, erythrocytes and platelets of healthy Japanese volunteers.
abstract: The purpose of this study was to determine both the selenium (Se) level and glutathione peroxidase (GSH-Px) activity in plasma, erythrocytes and platelets from 51 healthy Japanese individuals. The Se levels (mean +/- SD) of plasma, erythrocytes and platelets were 117.4 +/- 15.7 micrograms/L, 0.954 +/- 0.159 microgram/g hemoglobin, and 4.93 +/- 1.52 ng/mg protein, respectively, and GSH-Px activity was 318 +/- 50 U/L, 18.0 +/- 5.0 U/g hemoglobin, and 0.142 +/- 0.035 U/mg protein, respectively. There was a negative correlation between age and the platelet Se level in men (r = -0.761, p < 0.001), and a positive correlation between the plasma and platelet GSH-Px activities in women (r = 0.663, p < 0.001).
authors.affiliation: Department of Social & Preventive Medicine, Graduate School of Medicine, Kyoto University, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Matsuda
authors.forename: M
authors.initials: M
authors.lastname: Kimura
authors.forename: Y
authors.initials: Y
authors.lastname: Itokawa
mesh_terms: D000328:Adult; D001792:Blood Platelets / Q000201:enzymology / Q000378:metabolism*; D004912:Erythrocytes / Q000201:enzymology / Q000378:metabolism*; D005260:Female; D005979:Glutathione Peroxidase / Q000097:blood*; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012643:Selenium / Q000097:blood*
chemical_list: D005979:Glutathione Peroxidase; D012643:Selenium