Interaction of reactive oxygen species with DNA. A review.
Data on direct and indirect effects of reactive oxygen species on DNA are reviewed. The classification of the types of DNA oxidative damage and repair enzymes including glycosylases and endo- and exonucleases is presented. The regulatory function of reactive oxygen species and their role in carcinogenesis are discussed.
Peskin
A V
AV
Kol'tsov Institute of Developmental Biology, Russian Academy of Sciences, Moscow, Russia. peskin@ibrran.msk.su
D004247:DNA / Q000737:chemistry*; D004249:DNA Damage; D004260:DNA Repair; D009369:Neoplasms / Q000235:genetics / Q000473:pathology; D018384:Oxidative Stress; D017382:Reactive Oxygen Species
D017382:Reactive Oxygen Species; D004247:DNA