title: [Non-metastatic calcinosis localized in the prepuce. Clinicopathological study of a case and review of the literature].
abstract: Penis calcinosis is a rare pathology and only two previous cases have been reported in literature. We describe the clinicopathologic features of a case of nodular foreskin calcinosis in a 25-year-old man. The patient's history resulted negative for local trauma, inflammatory disorders or metabolic diseases. The mass measured up to 2 cm and was histologically constituted by multiple intradermic calcium deposits, whose deepest ones were surrounded by epithelioid histiocytes and multinucleated giant cells, with no evidence of any epithelial structures around none of them. These features were consistent with a non-metastatic calcinosis, likely idiopathic, even though also dystrophic calcinosis, observed at its end-stage, may show the same microscopic aspect. The exact idiopathic/dystrophic nosology is briefly discussed.
authors.affiliation: Dipartimento di Medicina Sperimentale e Patologia, Università La Sapienza di Roma.
authors.forename: A
authors.initials: A
authors.lastname: Corsi
authors.forename: P F
authors.initials: PF
authors.lastname: Salvi
authors.forename: F
authors.initials: F
authors.lastname: Diomesi Camassei
authors.forename: C
authors.initials: C
authors.lastname: Bosman
mesh_terms: D000328:Adult; D002114:Calcinosis / Q000175:diagnosis / Q000473:pathology*; D003937:Diagnosis, Differential; D015726:Giant Cells / Q000473:pathology; D006644:Histiocytes / Q000473:pathology; D006801:Humans; D008297:Male; D010409:Penile Diseases / Q000175:diagnosis / Q000473:pathology*; D010412:Penile Neoplasms / Q000175:diagnosis / Q000556:secondary
vernacular_title: Calcinosi non-metastatica localizzata del prepuzio. Studio clinicopatologico di un caso e revisione della letteratura.