Secretor status and ankylosing spondylitis.
OBJECTIVE
To assess the genetic association between secretor status and ankylosing spondylitis (AS).


METHODS
A restriction digest method for determining secretor status was developed; 166 patients with AS and 216 healthy British white controls were typed for secretor status using this method.


RESULTS
The frequency of nonsecretors among patients with AS (47/166, 28%) was not significantly different from controls (72/216, 33%).


CONCLUSIONS
Secretor status does not influence susceptibility to AS.
Pal
A
A
Wellcome Trust Centre for Human Genetics, Oxford, UK.
Hill
M
M
Wordsworth
P
P
Brown
M
M
D015331:Cohort Studies; D005647:Fucosyltransferases / Q000235:genetics*; D006801:Humans; D018928:Immunity, Mucosal; D013167:Spondylitis, Ankylosing / Q000097:blood / Q000235:genetics*; D000097631:Galactoside 2-alpha-L-fucosyltransferase
D005647:Fucosyltransferases; D000097631:Galactoside 2-alpha-L-fucosyltransferase