Beneficial hemodynamic effects of oral prostacyclin (PGI2) analogue, beraprost sodium, on a patient with primary pulmonary hypertension--a case report.
A 65-year-old woman was admitted to our hospital because of exertional dyspnea in 1987. A diagnosis of primary pulmonary hypertension was confirmed by right heart catheterization. She had received conventional therapy in the outpatient clinic. She was readmitted with the deterioration of exertional dyspnea in 1995. Stabilization of pulmonary hemodynamics, while not achieved with conventional therapy, was achieved with additive administration of an oral prostacyclin (PGI2) analogue, beraprost sodium.
Hashida
H
H
Second Department of Internal Medicine, Ehime University School of Medicine, Onsen-gun, Japan.
Hamada
M
M
Shigematsu
Y
Y
Ikeda
S
S
Kuwahara
T
T
Kawakami
H
H
Hara
Y
Y
Kodama
K
K
Kohara
K
K
Hiwada
K
K
D000284:Administration, Oral; D000368:Aged; D006328:Cardiac Catheterization; D004452:Echocardiography; D011464:Epoprostenol / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D005500:Follow-Up Studies; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D014665:Vasodilator Agents / Q000008:administration & dosage* / Q000627:therapeutic use
D014665:Vasodilator Agents; C048081:beraprost; D011464:Epoprostenol