Alteration in the activities of the membrane-integrated enzymes of polymorphonuclear leukocytes in obesity.
Oubain sensitive and insensitive adenosine triphosphatase showed decrease in their activities in the polymorphonuclear leukocytes of obese patients while the activity of acetylcholinesterase was found to be increased significantly. The contents of sodium, potassium and magnesium were found to be significantly decreased in polymorphonuclear leukocytes of obese patients. Polymorphonuclear leukocytes obtained from treated obese patients showed considerable restoration.
Das
R K
RK
Department of Biochemistry, Government Medical College, Nagpur.
Muddeshwar
M G
MG
D000110:Acetylcholinesterase / Q000378:metabolism*; D000328:Adult; D001067:Appetite Depressants / Q000627:therapeutic use; D015992:Body Mass Index; D017301:Ca(2+) Mg(2+)-ATPase / Q000378:metabolism*; D002462:Cell Membrane / Q000201:enzymology; D005277:Fenfluramine / Q000627:therapeutic use; D006801:Humans; D008274:Magnesium / Q000378:metabolism; D008297:Male; D009504:Neutrophils / Q000201:enzymology*; D009767:Obesity, Morbid / Q000188:drug therapy / Q000201:enzymology*; D011188:Potassium / Q000378:metabolism; D012964:Sodium / Q000378:metabolism; D000254:Sodium-Potassium-Exchanging ATPase / Q000378:metabolism*; D013054:Spectrophotometry, Atomic
D001067:Appetite Depressants; D005277:Fenfluramine; D012964:Sodium; D000110:Acetylcholinesterase; D017301:Ca(2+) Mg(2+)-ATPase; D000254:Sodium-Potassium-Exchanging ATPase; D008274:Magnesium; D011188:Potassium