title: Sequence of an HLA-B56 variant (B*5604) identified in the Korean population.
abstract: Three alleles encoding molecules with the B56 serologic specificity have been reported thus far. This study characterized an additional allele encoding a B56 molecule from two unrelated Korean individuals. The novel allele, B*5604, differs from B*5602 by a single nucleotide substitution at codon 103 (CTG-->GTG) resulting in an amino acid change from leucine to valine. The putative haplotype associated with the novel allele was A2-B*5604-Bw6-Cw7-DRB1*15-DRB5*02-DQA1*01-DQB 1*05.
authors.affiliation: Department of Clinical Pathology, College of Medicine, Hallym University, Seoul, Korea. leekw@www.hallym.or.kr
authors.forename: K W
authors.initials: KW
authors.lastname: Lee
authors.forename: N
authors.initials: N
authors.lastname: Steiner
authors.forename: C K
authors.initials: CK
authors.lastname: Hurley
mesh_terms: D000483:Alleles; D001483:Base Sequence; D004247:DNA / Q000235:genetics; D005785:Gene Conversion; D014644:Genetic Variation; D015235:HLA-B Antigens / Q000235:genetics*; D006239:Haplotypes; D006801:Humans; D007723:Korea; D016133:Polymerase Chain Reaction; D011110:Polymorphism, Genetic
chemical_list: D015235:HLA-B Antigens; C035270:HLA-B5 antigen; D004247:DNA