title: Influence of the volume of osteonecrosis on the outcome of core decompression of the femoral head.
abstract: OBJECTIVE
  To assess the outcome of core decompression in the treatment of osteonecrosis of the femoral head related to the volume of necrotic bone measured according to a previously reported method.
  
  
  METHODS
  Twenty hips corresponding to strictly Ficat stage II underwent magnetic resonance imaging and the volume of necrotic bone was expressed as a percentage of the volume of the entire head measured on each slice. All hips underwent core decompression and the outcome was evaluated at 24 months. The primary evaluation criterion was radiological appearance: the outcome was considered as good if the hip remained stage II and poor if the disease progressed.
  
  
  RESULTS
  Twenty four months after core decompression, half the cases remained stable and in half the disease had progressed. Outcome seemed to be related to the volume of necrotic bone (average 22% in the good outcome group versus 45% in the poor outcome group (p = 0.0051)) and was independent of risk factors, age, and histological type.
  
  
  CONCLUSIONS
  The volume of necrotic bone should be taken into account in the evaluation of any treatment, bearing in mind that in more than one third of cases this volume will probably decrease, especially at the beginning of the disease process.
authors.affiliation: Department of Rheumatology, University Hospital of Rangueil, Toulouse, France.
authors.forename: B
authors.initials: B
authors.lastname: Mazières
authors.forename: F
authors.initials: F
authors.lastname: Marin
authors.forename: P
authors.initials: P
authors.lastname: Chiron
authors.forename: L
authors.initials: L
authors.lastname: Moulinier
authors.forename: J M
authors.initials: JM
authors.lastname: Amigues
authors.forename: M
authors.initials: M
authors.lastname: Laroche
authors.forename: A
authors.initials: A
authors.lastname: Cantagrel
mesh_terms: D000328:Adult; D019299:Decompression, Surgical; D018450:Disease Progression; D005260:Female; D005271:Femur Head Necrosis / Q000473:pathology / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome