title: Crevicular fluid analysis around two failing dental implants: a clinical report.
abstract: The criteria for monitoring tissue health around endosseous implants remain subjective. Disagreement about which clinical measures of peri-implant health are of diagnostic value continues because of the complexity of the disease process and lack of validated measures of peri-implant health. Crevicular fluid analysis of various inflammatory mediators has been investigated as a means of providing objective criteria of tissue health. In this clinical report, the crevicular fluid levels of interleukin-1 beta (IL-1 beta), an inflammatory cytokine, were used to provide an objective measure of the peri-implant health and the effectiveness of treatment for a patient with two failing implants. The measurement of IL-1 beta may be an important supplement to clinical findings in establishing a diagnosis of peri-implantitis.
authors.affiliation: Department of Restorative Dentistry, University of California, San Francisco 94143-0758, USA.
authors.forename: D A
authors.initials: DA
authors.lastname: Curtis
authors.forename: R
authors.initials: R
authors.lastname: Kao
authors.forename: O
authors.initials: O
authors.lastname: Plesh
authors.forename: F
authors.initials: F
authors.lastname: Finzen
authors.forename: L
authors.initials: L
authors.lastname: Franz
mesh_terms: D000038:Abscess / Q000175:diagnosis / Q000628:therapy; D015415:Biomarkers / Q000032:analysis; D003131:Combined Modality Therapy; D003758:Dental Implantation, Endosseous / Q000009:adverse effects*; D019232:Dental Restoration Failure; D005260:Female; D005883:Gingival Crevicular Fluid / Q000737:chemistry*; D006801:Humans; D007375:Interleukin-1 / Q000032:analysis; D008875:Middle Aged; D011184:Postoperative Period; D014076:Tooth Diseases / Q000175:diagnosis / Q000628:therapy
chemical_list: D015415:Biomarkers; D007375:Interleukin-1