title: [Idiopathic ductopenia in adults as a cause of cryptogenic cirrhosis and complications of portal hypertension].
abstract: We describe a 56 years old male patient with long-term chronic liver disease of unknown etiology presenting with esophageal varices rupture. Prophylaxis of re-bleeding with propranolol and endoscopic sclerotherapy failed to prevent further haemorrhagic events and the placement of a transjugular intrahepatic portosystemic shunt (TIPS) was needed. The portal hemodynamic data revealed sinusoidal portal hypertension and the liver biopsy displayed ductopenic cholestasis. The patient met all criteria of idiopathic ductopenia. Subsequently, the jaundice worsened and the patient required liver transplantation.
authors.affiliation: Servicio de Gastroenterología, Hospital Xeral de Vigo.
authors.forename: D
authors.initials: D
authors.lastname: Rodríguez Martínez
authors.forename: C M
authors.initials: CM
authors.lastname: Fernández Rodríguez
authors.forename: I
authors.initials: I
authors.lastname: Rodríguez Prada
authors.forename: S
authors.initials: S
authors.lastname: Pereira Bueno
authors.forename: M
authors.initials: M
authors.lastname: Butrón
authors.forename: F
authors.initials: F
authors.lastname: Colina
mesh_terms: D001653:Bile Ducts, Intrahepatic; D001706:Biopsy; D002780:Cholestasis, Intrahepatic / Q000209:etiology* / Q000473:pathology; D006801:Humans; D006975:Hypertension, Portal / Q000209:etiology* / Q000473:pathology; D008099:Liver / Q000473:pathology; D008103:Liver Cirrhosis / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged
vernacular_title: Ductopenia idiopática del adulto como causa de cirrosis criptogenética y complicaciones de la hipertensión portal.