title: Metastatic small-cell carcinoma of rectum responding dramatically to combination chemotherapy.
abstract: Small-cell carcinoma of the rectum, is very rare with a dismal prognosis that follows a more aggressive course than the pure exocrine counterparts. As a result, survival is usually very poor. A male patient with metastatic disease is presented in this report. After receiving six cycles of combination chemotherapy regimen consisting of cyclophosphamide, adriamycin, and etoposide, he is in complete remission for >3 years. Although it is a single case, it shows that combination chemotherapy may achieve an excellent result even in a metastatic case of small-cell carcinoma of the rectum.
authors.affiliation: Hacettepe University Institute of Oncology, Ankara, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Yalçin
authors.forename: Y
authors.initials: Y
authors.lastname: Ozşik
authors.forename: G
authors.initials: G
authors.lastname: Tekuzman
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D018288:Carcinoma, Small Cell / Q000188:drug therapy* / Q000556:secondary*; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D008297:Male; D012004:Rectal Neoplasms / Q000188:drug therapy*; D012074:Remission Induction
chemical_list: D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide