Non-insulin dependent diabetes in children and adolescents: the therapeutic challenge.
Data are presented comparing non-insulin dependent diabetes mellitus (NIDDM) and insulin dependent diabetes mellitus (IDDM) in youth. Children and adolescents with NIDDM were predominantly Mexican-American, presented less frequently in ketoacidosis, had a greater frequency of family history of diabetes, had higher BMIs (27.4 vs 16.6 kg/m2), and had higher frequency of acanthosis nigricans (67% vs 1.2%). Logistical, social, and cultural challenges facing the physician treating children and adolescents with NIDDM are discussed, and treatment options for NIDDM in youth are briefly reviewed.
Jones
K L
KL
Department of Pediatrics, School of Medicine, University of California, San Diego, La Jolla 92093-0831, USA.
D000052:Acanthosis Nigricans / Q000453:epidemiology / Q000235:genetics / Q000628:therapy; D000293:Adolescent; D002140:California / Q000453:epidemiology; D002648:Child; D003466:Cultural Characteristics; D003710:Demography; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology* / Q000235:genetics / Q000628:therapy; D016883:Diabetic Ketoacidosis / Q000453:epidemiology / Q000235:genetics / Q000628:therapy; D003927:Diet, Diabetic; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D017058:Mexican Americans; D012959:Socioeconomic Factors