title: [Clinical course and prognostic factors in newborns with very low birth weight].
abstract: OBJECTIVE
  We report the results of survival and incidence of neurodevelopmental sequelae in a group of 249 infants treated in our hospital between 1986-91, whose birth weight was under 1,500 grams.
  
  
  METHODS
  We perform a follow-up at corrected ages of 3, 6, 10, 18, 36 months and 5 years thought results only included children followed until 18. Sequelae were classified in three groups, according to the disability degree.
  
  
  RESULTS
  Survival resulted to be 69.87% (174), 38.7% for the group under 1,000 grams and 84.7% for those over 1,000 grams. Sequelae were present in 22.6% (11.6% moderate and 10.9% severe). The incidence of severe sequelae was very different on basis of the birth weight, 25.8% for children under 1,000 grams, 13.9% for 1,000-1,249 grams and 1.6% for 1,250-1,500 grams.
  
  
  CONCLUSIONS
  Intracranial haemorrhage, hyperbilirubinemia, assisted ventilation and persistence of ductus arteriosus were significantly associated sequelae. We didn't find differences with respect to multiple pregnancy, seizures, sepsis or neonatal hypoxia.
authors.affiliation: Sección de Neonatología, Unidad de Salud Mental Infantil, Hospital General Universitario de Alicante.
authors.forename: C
authors.initials: C
authors.lastname: Tapia Collados
authors.forename: M A
authors.initials: MA
authors.lastname: Feret Siguile
authors.forename: J L
authors.initials: JL
authors.lastname: Serrano Martínez
authors.forename: J
authors.initials: J
authors.lastname: Sánchez Payá
authors.forename: I
authors.initials: I
authors.lastname: Palazón Azorín
authors.forename: A V
authors.initials: AV
authors.lastname: Alonso Barrena
authors.forename: B
authors.initials: B
authors.lastname: Jiménez Cobo
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology; D019102:Infant, Very Low Birth Weight; D011247:Pregnancy; D011379:Prognosis; D012189:Retrospective Studies
vernacular_title: Evolución y factores pronósticos en recién nacidos de muy bajo peso.