title: [Virtual simulation. First clinical results in patients with prostate cancer].
abstract: OBJECTIVE
  Investigation of options of virtual simulation in patients with localized prostate cancer.
  
  
  METHODS
  Twenty-four patients suffering from prostate cancer were virtual simulated. The clinical target volume was contoured and the planning target volume was defined after CT scan. The isocenter of the planning target volume was determined and marked at patient's skin. The precision of patients marking was controlled with conventional simulation after physical radiation treatment planning.
  
  
  RESULTS
  Mean differences of the patient's mark revealed between the 2 simulations in all room axes around 1 mm. The organs at risk were visualized in the digital reconstructed radiographs.
  
  
  CONCLUSIONS
  The precise patient's mark of the isocentre by virtual simulation allows to skip the conventional simulation. The visualisation of organs at risk leeds to an unnecessarily of an application of contrast medium and to a further relieve of the patient. The personal requirement is not higher in virtual simulation than in conventional CT based radiation treatment planning.
authors.affiliation: Klinik und Poliklinik für Strahlentherapie, Universitätsklinikum Charité, Berlin.
authors.forename: A
authors.initials: A
authors.lastname: Buchali
authors.forename: S
authors.initials: S
authors.lastname: Dinges
authors.forename: S
authors.initials: S
authors.lastname: Koswig
authors.forename: P
authors.initials: P
authors.lastname: Rosenthal
authors.forename: S
authors.initials: S
authors.lastname: Salk
authors.forename: C
authors.initials: C
authors.lastname: Harder
authors.forename: L
authors.initials: L
authors.lastname: Schlenger
authors.forename: V
authors.initials: V
authors.lastname: Budach
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003198:Computer Simulation; D006801:Humans; D008297:Male; D008875:Middle Aged; D008953:Models, Anatomic; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy*; D011881:Radiotherapy, Computer-Assisted / Q000379:methods*; D014057:Tomography, X-Ray Computed; D014584:User-Computer Interface
vernacular_title: Virtuelle Simulation. Erst klinische Ergebnisse bei Patienten mit Prostatakarzinom.