Salivary fluoride levels in overdenture wearers after topical fluoride gel application.
This study describes salivary fluoride levels after topical fluoride gel application on overdenture abutments. Fluoride levels were evaluated separately for the subjects with normal unstimulated salivary flow rate (n = 16) and for those with a low flow rate (n = 8). One drop of fluoride gel (Karigel-N, Lorvic) was placed in two abutment depressions of the duplicated overdenture, after which unstimulated whole saliva was collected for 30 minutes. Samples for fluoride analysis were taken at 5-minute intervals. Two additional samples were taken at 45 and 60 minutes. Fluoride concentration at the abutment-denture interface (remaining fluoride concentration) was measured at the end of the study. Salivary fluoride concentrations decreased gradually in both groups of subjects, but after 1 hour they remained at a higher level in subjects with low flow rates. Subjects' salivary flow rates correlated negatively with remaining fluoride concentration at the denture-tissue interface. Consequently, mean remaining fluoride concentration was significantly higher in subjects with low flow rate than in their normal counterparts.
Närhi
T O
TO
Department of Prosthodontics, University of Helsinki Institute of Dentistry, Finland.
Ettinger
R L
RL
Heilman
J R
JR
Wefel
J S
JS
D000368:Aged; D000704:Analysis of Variance; D000044:Dental Abutments; D003828:Denture, Overlay; D005260:Female; D005459:Fluorides / Q000032:analysis*; D005460:Fluorides, Topical / Q000008:administration & dosage*; D005782:Gels; D006801:Humans; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000737:chemistry* / Q000378:metabolism; D012636:Secretory Rate; D013997:Time Factors
D005460:Fluorides, Topical; D005782:Gels; D005459:Fluorides