[Effect of vitamin D3 and 20-hydroxyecdysone on the content of ATP, creatine phosphate, carnosine and Ca2+ in skeletal muscles].
The effect of vitamin D3, 20-hydroxyecdysone and extract from Serratula coronata containing 20-hydroxyecdysone on the level of basic metabolites in the skeletal muscles of rats has been studied. It was shown that development of D-hypovitaminosis is accompanied by the decrease in content of ATP, creatine phosphate, carnosine, and by the increase of Ca2+ content. Against the background of D-hypovitaminosis the 20-hydroxyecdysone and the extract from Serratula coronata which contains 20-hydroxyecdysone promote the increase of the amount of these metabolites up to the control of one and normalize Ca2+ content in them.
Kholodova
Iu D
IuD
A.V. Palladin Institute of Biochemistry, National Academy of Sciences of Ukraine, Kyiv.
Tugaĭ
V A
VA
Zimina
V P
VP
D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002336:Carnosine / Q000378:metabolism*; D002762:Cholecalciferol / Q000494:pharmacology*; D004441:Ecdysterone / Q000494:pharmacology*; D018482:Muscle, Skeletal / Q000187:drug effects / Q000378:metabolism; D010725:Phosphocreatine / Q000378:metabolism*; D010936:Plant Extracts / Q000494:pharmacology; D051381:Rats; D014808:Vitamin D Deficiency / Q000188:drug therapy / Q000378:metabolism
D010936:Plant Extracts; D010725:Phosphocreatine; D002762:Cholecalciferol; D004441:Ecdysterone; D002336:Carnosine; D000255:Adenosine Triphosphate; D002118:Calcium
Vliianie vitamina D3 i 20-gidroksiékdizona na soderzhanie ATP, kreatinfosfata, karnozina i Ca2+ v skeletnykh myshtsakh.