Diagnosis and treatment of a case of cutaneous cytomegalovirus infection with a dramatic clinical presentation.
A patient receiving long-term immunosuppressive treatment of systemic lupus erythematosus developed multiple large painful ulcers on her upper body. Histologic analysis showed cytopathic changes typical of cytomegalovirus infection that was confirmed by immunoperoxidase staining and polymerase chain reaction analyses. Treatment with ganciclovir and foscarnet resulted in clinical resolution. No recurrence was evident 6 months later.
Colsky
A S
AS
Department of Dermatology and Cutaneous Surgery, University of Miami School of Medicine, Florida 33136, USA.
Jegasothy
S M
SM
Leonardi
C
C
Kirsner
R S
RS
Kerdel
F A
FA
D000328:Adult; D001132:Arm; D001415:Back; D001706:Biopsy; D002908:Chronic Disease; D003131:Combined Modality Therapy; D003586:Cytomegalovirus Infections / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy; D012867:Skin / Q000473:pathology; D017193:Skin Diseases, Viral / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D012883:Skin Ulcer / Q000175:diagnosis / Q000209:etiology / Q000628:therapy
D007166:Immunosuppressive Agents