Gestational diabetes mellitus and glucose intolerance in a Mexican population.
OBJECTIVE
To determine the prevalence of gestational diabetes mellitus (GDM), glucose intolerance (GI) and macrosomia in a Latin Mexican population, using the one-step procedure proposed by the World Health Organization.


METHODS
Consecutive pregnant women (n = 667) who attended the antenatal clinic and delivered at the hospital were recruited after 24 weeks of gestation, mean 34.2 weeks, range 24-40 weeks. After a minimum of 3 days with a 150-g carbohydrate diet, a glucose load of 75 g was administered and 2 h after, a blood sample for glucose was taken, plasma was separated and immediately processed for glucose, using a glucose-oxidase method.


RESULTS
Twenty women were diagnosed with GDM (3%), 87 had GI (13%) and 560 had a normal glucose response (84%). Macrosomia occurred in two (10%) of GDM, in nine (10.3%) of GI, and in 29 (5.4%) gravidas with a normal response, respectively. Only one of the macrosomic infants whose mother had GI, had neonatal hypoglycemia and hyperbilirubinemia.


CONCLUSIONS
The overall prevalence of glucose abnormalities during pregnancy was 16%. GI in this group was associated to macrosomia at the same rate as GDM.
Forsbach
G
G
Department of Endocrinology, Hospital de Gineco-Obstetricia Dr. I. Morones, Monterrey, Mexico.
Cantú-Diaz
C
C
Vázquez-Lara
J
J
Villanueva-Cuellar
M A
MA
Alvarez y García
C
C
Rodríguez-Ramírez
E
E
D000328:Adult; D016640:Diabetes, Gestational / Q000453:epidemiology*; D005260:Female; D005320:Fetal Macrosomia / Q000453:epidemiology; D018149:Glucose Intolerance / Q000453:epidemiology*; D005951:Glucose Tolerance Test; D006801:Humans; D007231:Infant, Newborn; D008800:Mexico / Q000453:epidemiology; D011247:Pregnancy; D015995:Prevalence