title: Simultaneous angle closure in twins.
abstract: OBJECTIVE
  This article reports identical twin sisters who were found to have acute angle-closure glaucoma at the same time.
  
  
  METHODS
  Two case reports.
  
  
  RESULTS
  Two 73-year-old identical twin sisters presented to the emergency room with a complaint of decreased vision and eye pain after having been in a fist fight with each other the previous night. One sister exhibited signs of angle-closure glaucoma with an intraocular pressure > 50 mmHg in the left eye, while her twin sister presented with bilateral angle-closure glaucoma and similar intraocular pressures. Both patients were treated with anti-glaucoma medications and bilateral laser iridotomies.
  
  
  CONCLUSIONS
  Polygenetic factors influence the configuration of the anterior chamber, but other environmental factors contribute to the risk of developing primary angle-closure glaucoma. Potentially occludable angles are more common in individuals with a first-degree relative with acute angle closure. Screening of these patients (especially twins) for occludable angles is recommended.
authors.affiliation: Glaucoma Service, Northwestern University, Chicago, Illinois, USA.
authors.forename: D
authors.initials: D
authors.lastname: Talluto
authors.forename: M
authors.initials: M
authors.lastname: Feith
authors.forename: S
authors.initials: S
authors.lastname: Allee
mesh_terms: D000086:Acetazolamide / Q000627:therapeutic use; D000208:Acute Disease; D000368:Aged; D002257:Carbonic Anhydrase Inhibitors / Q000627:therapeutic use; D004200:Diseases in Twins; D004234:Diuretics, Osmotic / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D005260:Female; D015812:Glaucoma, Angle-Closure / Q000188:drug therapy / Q000235:genetics* / Q000601:surgery; D006801:Humans; D007429:Intraocular Pressure; D007498:Iris / Q000601:surgery; D053685:Laser Therapy; D008353:Mannitol / Q000627:therapeutic use; D008916:Miotics / Q000627:therapeutic use; D010862:Pilocarpine / Q000627:therapeutic use
chemical_list: D002257:Carbonic Anhydrase Inhibitors; D004234:Diuretics, Osmotic; D008916:Miotics; D010862:Pilocarpine; D008353:Mannitol; D000086:Acetazolamide