Too many COX (cyclo-oxygenase) spoil the broth: aspirin-sensitive asthma and 5-lypoxygenase.
Mitchell
J A
JA
Belvisi
M G
MG
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D001094:Arachidonate 5-Lipoxygenase / Q000378:metabolism; D001241:Aspirin / Q000009:adverse effects*; D001249:Asthma / Q000139:chemically induced / Q000201:enzymology* / Q000378:metabolism; D004789:Enzyme Activation; D007527:Isoenzymes / Q000378:metabolism*; D015289:Leukotrienes / Q000096:biosynthesis; D008168:Lung / Q000201:enzymology* / Q000378:metabolism; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism*; D011453:Prostaglandins / Q000096:biosynthesis
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007527:Isoenzymes; D015289:Leukotrienes; D011453:Prostaglandins; D001094:Arachidonate 5-Lipoxygenase; D011451:Prostaglandin-Endoperoxide Synthases; D001241:Aspirin