[Recurrent urological cancer--diagnose and treatment].
Clinical efforts to spare bladder function even in the case of muscle invasive recurrent bladder cancer is taking. Early detection of recurrence is essential for bladder sparing, and both urinary NMP22 and BTA are thought to have potency to detect recurrence of bladder cancer earlier than urinary cytology. Intravesical administration of BCG for superficial bladder cancer and intraarterial injection of chemoagents (Methotrexate and Cisplatin) with radiation for muscle invasive bladder cancer are thought to play important roles in sparing the bladder. Early detection of recurrent prostate cancer is becoming easier by ultrasensitive PSA assay. Though the value of early detection of recurrence is not proven since the benefits of early hormonal treatment have not yet been established, that should be a good indicator to evaluate new and coming treatments and play a important role to develop an effective treatment for recurrent prostate cancer.
Takeshima
H
H
Dept. of Urology, University of Tsukuba, Japan.
Akaza
H
H
D000005:Abdomen / Q000000981:diagnostic imaging; D000283:Administration, Intravesical; D000951:Antigens, Neoplasm / Q000032:analysis; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001500:BCG Vaccine / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000032:analysis*; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D003558:Cystoscopy; D004317:Doxorubicin / Q000008:administration & dosage; D006801:Humans; D008297:Male; D008727:Methotrexate / Q000008:administration & dosage; D009364:Neoplasm Recurrence, Local / Q000628:therapy*; D009687:Nuclear Proteins / Q000032:analysis; D017430:Prostate-Specific Antigen / Q000097:blood; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D014463:Ultrasonography; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D014747:Vinblastine / Q000008:administration & dosage
D000951:Antigens, Neoplasm; D001500:BCG Vaccine; D014408:Biomarkers, Tumor; D009687:Nuclear Proteins; C100379:nuclear matrix protein 22; D014747:Vinblastine; D004317:Doxorubicin; D017430:Prostate-Specific Antigen; D002945:Cisplatin; D008727:Methotrexate