Effects of photoperiod on brain corticosteroid receptors and the stress response in the golden hamster (Mesocricetus auratus).
Following exposure to short daylengths, in golden hamsters, changes in basal adrenal glucocorticoid secretion are associated with a significant increase in Type I receptor binding, and are preceded by alterations in the stress-induced release of glucocorticoids, which is one of the major modes of operation of the hypothalamo-pituitary-adrenocortical axis (HPA). These results lend support to the hypothesis that corticosteroid receptors, and in particular the Type I receptor subtype, play a central role in the regulation of circadian and circannual rhythms of the HPA.
Ronchi
E
E
Laboratory of Neuroendocrinology, Rockefeller University, New York, NY 10021, USA.
Spencer
R L
RL
Krey
L C
LC
McEwen
B S
BS
D000315:Adrenalectomy; D000818:Animals; D001923:Brain Chemistry / Q000502:physiology*; D002540:Cerebral Cortex / Q000737:chemistry / Q000502:physiology; D003345:Corticosterone / Q000097:blood; D006224:Cricetinae; D006624:Hippocampus / Q000737:chemistry / Q000502:physiology; D006854:Hydrocortisone / Q000378:metabolism / Q000494:pharmacology; D007031:Hypothalamus / Q000737:chemistry / Q000502:physiology; D008297:Male; D008647:Mesocricetus; D017440:Photoperiod; D010913:Pituitary-Adrenal System / Q000502:physiology; D011987:Receptors, Steroid / Q000819:agonists / Q000032:analysis*; D013312:Stress, Physiological / Q000378:metabolism*; D014316:Tritium
D011987:Receptors, Steroid; D014316:Tritium; D003345:Corticosterone; D006854:Hydrocortisone