Advances in fluorescent in situ hybridisation.
Recent advances in fluorescent in situ hybridisation included the generation of allele-specific probes, bar-coded chromosomes, and the visualisation of chromosome territories and genes within the nucleus. One major advance has been our ability to visualise and make precise and reproducible measurements from stretched DNA molecules prepared directly from human cells.
Ekong
R
R
MRC Human Biochemical Genetics Unit, Galton Laboratory, London, UK. r.ekong@galton.ucl.ac.uk
Wolfe
J
J
D002875:Chromosomes; D003582:Cytogenetics / Q000379:methods; D015342:DNA Probes; D005826:Genetics, Medical / Q000379:methods*; D006801:Humans; D017403:In Situ Hybridization / Q000379:methods*; D007621:Karyotyping
D015342:DNA Probes