title: Percutaneous removal of malignant mammographic lesions at stereotactic vacuum-assisted biopsy.
abstract: OBJECTIVE
  To determine whether complete percutaneous removal of a malignant lesion detected at mammography ensures complete excision of the carcinoma histopathologically.
  
  
  METHODS
  A retrospective review was performed of 135 lesions in which stereotactic biopsy was performed with a directional, vacuum biopsy instrument and an 11-gauge probe followed by mammography. Carcinoma was diagnosed at stereotactic biopsy in 51 (38%) lesions. In 15 (29%) carcinomas, the lesion seen at mammography was removed at stereotactic biopsy. Surgical findings were available for correlation with biopsy and imaging findings in all 15 cases. Mammographic and histopathologic findings were reviewed.
  
  
  RESULTS
  Mammographic findings were calcifications in 11 lesions and a mass in four lesions. The median lesion size was 0.7 cm (range, 0.2-1.4 cm), and the median number of biopsy specimens was 15 (range, 10-22 specimens). Histopathologic findings at stereotactic biopsy were ductal carcinoma in situ in 12 lesions and infiltrating ductal carcinoma in three. Surgery revealed residual carcinoma in 11 (73%) of 15 lesions, including all three infiltrating ductal carcinomas and eight of 12 ductal carcinoma in situ lesions.
  
  
  CONCLUSIONS
  Complete removal of the mammographic lesion does not ensure complete excision of the carcinoma.
authors.affiliation: Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.
authors.forename: L
authors.initials: L
authors.lastname: Liberman
authors.forename: D D
authors.initials: DD
authors.lastname: Dershaw
authors.forename: P P
authors.initials: PP
authors.lastname: Rosen
authors.forename: E A
authors.initials: EA
authors.lastname: Morris
authors.forename: A F
authors.initials: AF
authors.lastname: Abramson
authors.forename: P I
authors.initials: PI
authors.lastname: Borgen
mesh_terms: D001707:Biopsy, Needle / Q000295:instrumentation / Q000379:methods*; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D002278:Carcinoma in Situ / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008327:Mammography / Q000379:methods; D008875:Middle Aged; D018365:Neoplasm, Residual; D012189:Retrospective Studies; D014618:Vacuum