Reduction of alkyl (2-oxocyclohexyl)acetates by baker's yeast.
Baker's yeast reduction of methyl and ethyl (2-oxocyclohexyl) acetates proceeded with enantio- and diastereo-selectivity, affording the corresponding (2S)-trans-alcohols (major), (2S)-cis-alcohols (minor), and the unaltered (1S)-ketones with high optical purity.
Ganaha
M
M
Department of Agricultural Chemistry, Faculty of Agriculture, Ehime University, Matsuyama, Japan.
Funabiki
Y
Y
Motoki
M
M
Yamauchi
S
S
Kinoshita
Y
Y
D000085:Acetates / Q000378:metabolism*; D010084:Oxidation-Reduction; D012441:Saccharomyces cerevisiae / Q000378:metabolism*
D000085:Acetates