title: [Manifestations, diagnosis and treatment of non-tuberculous mycobacterial infections in non-immunodepressed patients].
abstract: Non-tuberculous mycobacteria (NTM) can be the etiologic agents of chronic pulmonary disease, lymphadenitis, skin and soft-tissue infection and disseminated disease in non-immunocompromised patients. The recognition of disease needs repeated isolation of the NTM from bronchopulmonary secretions or from tissue biopsies, and its identification by specific laboratory methods. A wide spectrum of clinical presentations and severity of disease can be found, from spontaneous healing to progressive and destructive lung disease, and death, according to predisposing conditions and mycobacterial species. The choice of surgical and drug treatment will depend on identification of specific pathogen and clinical evaluation.
authors.affiliation: Cliniques de l'Université Catholique de Louvain Mont-Godinne, Yvoir, Belgique.
authors.forename: L
authors.initials: L
authors.lastname: Delaunois
authors.forename: M G
authors.initials: MG
authors.lastname: Garrino
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use; D001706:Biopsy; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology; D002423:Cause of Death; D018450:Disease Progression; D006801:Humans; D007121:Immunocompetence; D008199:Lymphadenitis / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology* / Q000601:surgery; D015270:Mycobacterium avium-intracellulare Infection / Q000175:diagnosis / Q000188:drug therapy; D019909:Mycobacterium kansasii / Q000145:classification; D019912:Mycobacterium xenopi / Q000145:classification; D009170:Nontuberculous Mycobacteria / Q000145:classification / Q000502:physiology; D012307:Risk Factors; D018461:Soft Tissue Infections / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D014376:Tuberculosis / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology* / Q000601:surgery; D014382:Tuberculosis, Cutaneous / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery; D014388:Tuberculosis, Lymph Node / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery
chemical_list: D000995:Antitubercular Agents
vernacular_title: Manifestations, diagnostics et traitements des mycobactérioses non tuberculeuses chez le sujet non immunodéprimé.