[New medical treatments of systemic idiopathic fibrosis].
Medical treatment of systemic idiopathic fibrosis is first based on steroid therapy, of which efficacy is well known for nearly 75% of cases of retroperitoneal fibrosis, but les certain for the other localisations of the disease. Studies on the immuno-pathological mechanism of systemic fibrosis have led to immunosuppressive drug use, such as azathioprin, cyclophosphamide and methotrexate. Tamoxifen has been tried because of its efficacy on desmoid tumors and seems to be of great interest. Attention is focused on fibrosing cervicitis which may also be treated with immunosuppressive drugs.
Bréchignac
X
X
Service de médecine interne, hôpital Jean-Minjoz, Besançon, France.
de Wazières
B
B
Desmurs
H
H
Gil
H
H
Berthier
S
S
Levrat
R
R
Dupond
J L
JL
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use*; D004965:Estrogen Antagonists / Q000627:therapeutic use*; D005355:Fibrosis; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D009333:Neck; D012185:Retroperitoneal Fibrosis / Q000188:drug therapy*
D000305:Adrenal Cortex Hormones; D004965:Estrogen Antagonists; D007166:Immunosuppressive Agents
Les nouveaux traitements médicaux des fibroses systémiques idiopathiques.