title: [Clarifying the crystal structure of hepatitis C virus NS3/NS4A protease complex--basics for the development of specific HCV protease inhibitors?].
authors.affiliation: I. Medizinische Klinik, Christian-Albrechts-Universität, Kiel.
authors.forename: R
authors.initials: R
authors.lastname: Günther
authors.forename: W E
authors.initials: WE
authors.lastname: Schmidt
mesh_terms: D016174:Hepacivirus / Q000737:chemistry*; D006526:Hepatitis C / Q000188:drug therapy / Q000821:virology*; D006801:Humans; D011480:Protease Inhibitors / Q000138:chemical synthesis* / Q000627:therapeutic use; D013329:Structure-Activity Relationship; D017361:Viral Nonstructural Proteins / Q000032:analysis* / Q000037:antagonists & inhibitors; D012697:Serine Endopeptidases; D043583:Nucleoside-Triphosphatase; D053487:DEAD-box RNA Helicases; D000085242:Viral Proteases
chemical_list: D011480:Protease Inhibitors; D017361:Viral Nonstructural Proteins; C084422:NS3 protein, hepatitis C virus; D012697:Serine Endopeptidases; D043583:Nucleoside-Triphosphatase; D053487:DEAD-box RNA Helicases; D000085242:Viral Proteases; C093542:NS4 protein, hepatitis C virus
vernacular_title: Aufklärung der Kristallstruktur des Hepatitis-C-Virus-NS3/NS4A-Proteasekomplexes-Grundlage für die Entwicklung spezifischer HCV-Proteaseinhibitoren?