title: Nonlinear effects and a cascade of radical events leading to laser-specific generation of active oxygen species.
abstract: Laser photolysis of benzoyl radical precursors (such as PhCOC[OH]R2) in oxygen-containing solutions leads to a laser-specific cascade of oxidative events in which benzoyl peroxyl radicals undergo self-reaction, ultimately leading to the sequential formation of benzoyloxyl, phenyl and phenyl peroxyl radicals. Thus, photoreactions producing benzoyl (PhCO) radicals lead to PhOO under conditions where benzoyl radicals do not decarbonylate. These reactions require the high-intensity conditions that can only be achieved under pulsed laser excitation; yet, they do not involve any multiphoton processes. Type I mechanisms of this type may be of importance as new laser-based therapeutic technologies are developed.
authors.affiliation: Department of Chemistry, University of Ottawa, Ontario, Canada.
authors.forename: T
authors.initials: T
authors.lastname: Hancock-Chen
authors.forename: J C
authors.initials: JC
authors.lastname: Scaiano
mesh_terms: D001585:Benzoyl Peroxide / Q000737:chemistry*; D005609:Free Radicals / Q000737:chemistry; D007834:Lasers; D010777:Photochemistry / Q000379:methods; D010782:Photolysis; D017382:Reactive Oxygen Species
chemical_list: D005609:Free Radicals; D017382:Reactive Oxygen Species; D001585:Benzoyl Peroxide