[Effect of oxygen inhalation on hemodynamics in chronic thromboembolic pulmonary hypertension].
OBJECTIVE
This study evaluates the haemodynamic effects of oxygen inhalation on pulmonary artery pressure and pulmonary vascular resistance in patients with chronic thromboembolic pulmonary hypertension.


METHODS
In 47 patients with chronic thromboembolic pulmonary hypertension haemodynamic parameters were measured before and after oxygen inhalation.


RESULTS
In moderately severe and severe pulmonary hypertension oxygen inhalation significantly reduced mean pulmonary artery pressure by about 11.1% and 4.6%, respectively. However, pulmonary vascular resistance was not significantly affected. Oxygen saturation improved and heart rate was reduced. Cardiac index decreased in severe pulmonary hypertension. Systemic vascular resistance increased.


CONCLUSIONS
We conclude that oxygen inhalation reduces pulmonary artery pressure and improves oxygen supply in patients with moderately severe and severe chronic thromboembolic pulmonary hypertension.
Pitton
M B
MB
Klinik für Radiologie, Johannes Gutenberg-Universität Mainz.
Düber
C
C
Mayer
E
E
Thelen
M
M
D001794:Blood Pressure; D002245:Carbon Dioxide / Q000097:blood; D002302:Cardiac Output; D002908:Chronic Disease; D005260:Female; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000503:physiopathology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010102:Oxygen Inhalation Therapy; D010313:Partial Pressure; D011651:Pulmonary Artery; D011652:Pulmonary Circulation; D011655:Pulmonary Embolism / Q000503:physiopathology* / Q000628:therapy*; D014655:Vascular Resistance
D002245:Carbon Dioxide; D010100:Oxygen
Auswirkungen der Sauerstoffinhalation auf die Hämodynamik bei chronischer thromboembolischer pulmonaler Hypertonie.