title: Normal S cone electroretinogram b-wave in Oguchi's disease.
abstract: OBJECTIVE
  The short wavelength sensitive (S) cone electroretinograms (ERGs) were examined in two patients with Oguchi's disease to study S cone function.
  
  
  METHODS
  Ganzfeld colour flashes under bright white background illumination were used to elicit S cone, and mixed long (L) and middle (M) wavelength sensitive cone ERGs.
  
  
  RESULTS
  The S cone ERG b-wave was normal with short wavelength stimuli with normal L and M cone responses in both patients.
  
  
  CONCLUSIONS
  These ERG results indicate that the S cone system as well as the L and M cone system is not defective in Oguchi's disease, while the S cone responses are not detectable in the complete type of congenital stationary night blindness as reported previously. The results imply that there is a significant difference in the way the S cone system is affected in different forms of stationary night blindness, and that the S cone and rod do not share the same arrestin system.
authors.affiliation: Toho University Sakura Hospital, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Yamamoto
authors.forename: M
authors.initials: M
authors.lastname: Hayashi
authors.forename: S
authors.initials: S
authors.lastname: Takeuchi
authors.forename: Y
authors.initials: Y
authors.lastname: Shirao
authors.forename: K
authors.initials: K
authors.lastname: Kita
authors.forename: K
authors.initials: K
authors.lastname: Kawasaki
mesh_terms: D000328:Adult; D004596:Electroretinography; D005260:Female; D006801:Humans; D008875:Middle Aged; D009755:Night Blindness / Q000503:physiopathology*; D010775:Photic Stimulation; D017949:Retinal Cone Photoreceptor Cells / Q000503:physiopathology*; D017948:Retinal Rod Photoreceptor Cells / Q000503:physiopathology