Synthesis of some chroman derivatives and preliminary investigation on their vasodilatory activity.
In this study, some N'-(chroman-4-yliden)-4-aryl-2-thiazolylhidrazide derivatives were synthesized. Their structures were elucidated by IR, NMR and microanalyses. The vasodilatory activities of the compounds obtained were examined in vitro.
Turan-Zitouni
G
G
University of Anadolu, Faculty of Pharmacy, Eskişehir, Turkey.
Chevallet
P
P
Erol
K
K
Boydağ
B S
BS
D000818:Animals; D001158:Arteries / Q000187:drug effects; D002839:Chromans / Q000138:chemical synthesis* / Q000494:pharmacology; D066298:In Vitro Techniques; D009638:Norepinephrine / Q000037:antagonists & inhibitors / Q000494:pharmacology; D012756:Sheep; D013055:Spectrophotometry, Infrared; D014662:Vasoconstrictor Agents / Q000037:antagonists & inhibitors / Q000494:pharmacology; D014665:Vasodilator Agents / Q000138:chemical synthesis* / Q000494:pharmacology
D002839:Chromans; D014662:Vasoconstrictor Agents; D014665:Vasodilator Agents; D009638:Norepinephrine