title: Adjunctive use of olanzapine in mood disorders: five case reports.
abstract: Olanzapine has emerged as an atypical antipsychotic with few side effects and potentially superior efficacy in the treatment of schizophrenia. To our knowledge there have been few published reports of olanzapine in the treatment of mood disorders. We report on the adjunctive use of this medication in three subjects with mania and two with depression. Response occurred rapidly and patients tolerated the medication. Olanzapine offers promise in the treatment of mood disorders.
authors.affiliation: Department of Psychiatry and Behavioral Science, Duke University Medical Center Durham, North Carolina, USA.
authors.forename: R H
authors.initials: RH
authors.lastname: Weisler
authors.forename: E P
authors.initials: EP
authors.lastname: Ahearn
authors.forename: J R
authors.initials: JR
authors.lastname: Davidson
authors.forename: C D
authors.initials: CD
authors.lastname: Wallace
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D001569:Benzodiazepines; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000523:psychology; D003702:Delusions / Q000188:drug therapy / Q000523:psychology; D003865:Major Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008875:Middle Aged; D000077152:Olanzapine; D010890:Pirenzepine / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D012008:Recurrence
chemical_list: D014150:Antipsychotic Agents; D001569:Benzodiazepines; D010890:Pirenzepine; D000077152:Olanzapine