title: [Signal-enhanced color-coded duplex sonography of reactively and metastatically enlarged lymph nodes].
abstract: OBJECTIVE
  Prospective comparison of B-mode-, plain and signal-enhanced colour Doppler ultrasound to evaluate new criteria for assessment of the tumour status of enlarged cervical lymph nodes.
  
  
  METHODS
  Colour Doppler sonography was performed before and after application of d-galactose in 35 patients with suspected lymph node metastases of the neck. Sonomorphology was analysed qualitatively, maximal flow rate, pulsatility index and resistance index were determined quantitatively.
  
  
  RESULTS
  Signal enhanced Doppler revealed a typical vessel morphology of the lymph nodes facilitating differential diagnosis. In 23%, vascularisation of the lymph nodes was only visible after application of the signal-enhancing agent (benign: 44%, malignant: 5%). The measurement of flow velocity and the calculation of RI and PI did not lead to a reliable differentiation between malignant and benign lymph nodes whereas B-mode sonography yielded highly valid results.
  
  
  CONCLUSIONS
  The application of d-galactose facilitates differentiation between malignant and benign lymph nodes.
authors.affiliation: Strahlenklinik und Poliklinik, Medizinische Fakultät, Humboldt-Universität zu Berlin.
authors.forename: R J
authors.initials: RJ
authors.lastname: Schröder
authors.forename: J
authors.initials: J
authors.lastname: Mäurer
authors.forename: N
authors.initials: N
authors.lastname: Hidajat
authors.forename: C
authors.initials: C
authors.lastname: Willam
authors.forename: B
authors.initials: B
authors.lastname: Hell
authors.forename: S
authors.initials: S
authors.lastname: Weber
authors.forename: T
authors.initials: T
authors.lastname: Vogl
authors.forename: R
authors.initials: R
authors.lastname: Felix
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D005260:Female; D005690:Galactose; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary*; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging*; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging*; D008228:Lymphoma, Non-Hodgkin / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D018615:Ultrasonography, Doppler, Color / Q000379:methods*
chemical_list: D005690:Galactose
vernacular_title: Signalverstärkte farbkodierte Duplexsonographie reaktiv und metastatisch vergrösserter Lymphknoten.