title: Severe muscle damage induced by high carbohydrate intake from elemental diet in a patient with Crohn's disease.
abstract: Crohn's disease is associated with complications in multiple organs. However, there are very few reported cases of patients with Crohn's disease with muscle symptoms and/or high serum creatine phospho-kinase (CPK) levels. We report here a patient with Crohn's disease who experienced skeletal muscle damage with extremely high serum CPK level during treatment with an elemental diet. The non-parenteral administration of large amounts of carbohydrate and limited glycogen degradation capability may be a possible causative mechanism for this elemental diet-induced muscle damage.
authors.affiliation: Department of Medicine, Kobe University School of Medicine, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Waki
authors.forename: C
authors.initials: C
authors.lastname: Kawanami
authors.forename: F
authors.initials: F
authors.lastname: Kanda
authors.forename: Y
authors.initials: Y
authors.lastname: Uenoyama
authors.forename: T
authors.initials: T
authors.lastname: Maekawa
authors.forename: H
authors.initials: H
authors.lastname: Fukui
authors.forename: A
authors.initials: A
authors.lastname: Okada
authors.forename: Y
authors.initials: Y
authors.lastname: Matsushima
authors.forename: K
authors.initials: K
authors.lastname: Kishi
authors.forename: Y
authors.initials: Y
authors.lastname: Kinoshita
authors.forename: T
authors.initials: T
authors.lastname: Chiba
mesh_terms: D000328:Adult; D003402:Creatine Kinase / Q000097:blood; D003424:Crohn Disease / Q000150:complications* / Q000178:diet therapy* / Q000201:enzymology; D005260:Female; D005526:Food, Formulated / Q000009:adverse effects*; D006801:Humans; D018482:Muscle, Skeletal / Q000293:injuries* / Q000473:pathology*; D009748:Nutrition Disorders / Q000150:complications* / Q000201:enzymology
chemical_list: D003402:Creatine Kinase