title: Spinal cord infection: myelitis and abscess formation.
abstract: OBJECTIVE
  Our purpose was to describe the MR findings and evolution of spinal cord abscess and to define those MR features that allow differentiation of cord infection from other intramedullary abnormalities.
  
  
  METHODS
  We retrospectively reviewed the MR studies of all patients in whom intramedullary spinal cord abscess was proved either by blood or cerebrospinal fluid culture or by serologic examination at our institution between January 1988 and January 1996. The study group included four adults and two children, 7 to 74 years old (mean age, 38 years).
  
  
  RESULTS
  Initial MR studies showed intramedullary high signal on T2-weighted sequences with poorly defined marginal enhancement on T1-weighted images. On follow-up contrast-enhanced T1-weighted studies, the lesions had well-defined enhancing margins with central low signal intensity. After the initiation of therapy, T2 signal abnormalities decreased markedly and contrast-enhanced studies showed ring enhancement. These T1 findings resolved with treatment over serial studies in four patients. The organisms identified were Streptococcus milleria, S pyogenes, atypical mycobacteria, Mycobacterium tuberculosis, and Schistosoma mansoni (both children).
  
  
  CONCLUSIONS
  A characteristic sequence of imaging findings aids in the differentiation of cord infection from other intramedullary lesions.
authors.affiliation: Department of Radiology, University of Michigan Hospitals, Ann Arbor, USA.
authors.forename: K J
authors.initials: KJ
authors.lastname: Murphy
authors.forename: J A
authors.initials: JA
authors.lastname: Brunberg
authors.forename: D J
authors.initials: DJ
authors.lastname: Quint
authors.forename: P H
authors.initials: PH
authors.lastname: Kazanjian
mesh_terms: D000038:Abscess / Q000175:diagnosis*; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis; D009187:Myelitis / Q000175:diagnosis*; D012189:Retrospective Studies; D012555:Schistosomiasis mansoni / Q000175:diagnosis; D013116:Spinal Cord / Q000473:pathology; D013118:Spinal Cord Diseases / Q000175:diagnosis*; D013290:Streptococcal Infections / Q000175:diagnosis; D013297:Streptococcus pyogenes; D014399:Tuberculosis, Spinal / Q000175:diagnosis