title: Hypertension and hypothyroidism.
abstract: Correction of the causes of secondary forms of hypertension usually restores blood pressure to normal. Hypothyroidism is a potentially important but overlooked cause of hypertension and restoration of euthyroidism with thyroxine therapy usually results in a substantial reduction in both systolic and diastolic blood pressure, especially in younger subjects. The mechanism of hypertension in hypothyroidism is not completely understood: changes in circulating catecholamines, their receptors and the renin-angiotensin-aldosterone system have all been implicated. Effective treatment with thyroxine is readily available and inexpensive.
authors.affiliation: University of Sheffield, Department of Medicine, Northern General Hospital, UK.
authors.forename: A K
authors.initials: AK
authors.lastname: Fletcher
authors.forename: A P
authors.initials: AP
authors.lastname: Weetman
mesh_terms: D006801:Humans; D006973:Hypertension / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy; D007037:Hypothyroidism / Q000150:complications*; D015995:Prevalence