title: Transient compartmental expression of neurocan in the developing striatum of the rat.
abstract: The expression of the chondroitin sulfate proteoglycan neurocan was examined in the developing striatum of the rat and compared with the distribution of dopaminergic terminals. Neurocan immunoreactivity shows a homogeneous pattern in the embryonic striatum. In the postnatal striatum, neurocan was first expressed within the matrix but not the patch compartments, and subsequently within both. These results suggest that chondroitin sulfate proteoglycans are involved in formation of connections between the substantia nigra and striatum.
authors.affiliation: Laboratoire de Neurobiologie du Développement, LAPSEN, INSERM U318, Université Joseph Fourier, CERMO, Grenoble, France. Igor.Charvet@ujf-grenoble.fr
authors.forename: I
authors.initials: I
authors.lastname: Charvet
authors.forename: F J
authors.initials: FJ
authors.lastname: Hemming
authors.forename: C
authors.initials: C
authors.lastname: Feuerstein
authors.forename: R
authors.initials: R
authors.lastname: Saxod
mesh_terms: D000367:Age Factors; D000818:Animals; D000911:Antibodies, Monoclonal; D011508:Chondroitin Sulfate Proteoglycans / Q000032:analysis* / Q000096:biosynthesis / Q000276:immunology; D002809:Chondroitin Sulfates / Q000032:analysis / Q000378:metabolism; D003342:Corpus Striatum / Q000737:chemistry / Q000196:embryology / Q000254:growth & development; D004298:Dopamine / Q000032:analysis / Q000378:metabolism; D037181:Lectins, C-Type; D009419:Nerve Tissue Proteins / Q000032:analysis* / Q000096:biosynthesis / Q000276:immunology; D058580:Neurocan; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000911:Antibodies, Monoclonal; D011508:Chondroitin Sulfate Proteoglycans; D037181:Lectins, C-Type; D009419:Nerve Tissue Proteins; D058580:Neurocan; C076817:NCAN protein, human; D002809:Chondroitin Sulfates; D004298:Dopamine