[Liver and spleen macrophages function in patients with chronic leukemia].
Macrophagal function of the liver and the spleen has been studied using dynamic scintigraphy in 46 patients with chronic lymphatic and myeloid leukemia. There was an increase in the share of the spleen in total accumulation of radionuclide, shortening of the time of its capture by the liver macrophages and an increase in the indices of hepatic and splenic clearance with the same total time of drug elimination from the blood. The above changes became more distinct with leukemia progression and seem to be more severe in chronic myeloid leukemia.
Litvinov
A V
AV
Miliagin
V A
VA
Savchenko
V G
VG
D000328:Adult; D000368:Aged; D018450:Disease Progression; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000000981:diagnostic imaging / Q000503:physiopathology*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008099:Liver / Q000502:physiology*; D008264:Macrophages / Q000000981:diagnostic imaging / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011877:Radionuclide Imaging; D013154:Spleen / Q000502:physiology*; D017556:Technetium Compounds / Q000493:pharmacokinetics
D017556:Technetium Compounds
Sostoianie makrofagal'noĭ funktsii pecheni i selezenki u bol'nykh khronicheskimi leĭkozami.