title: [Basaliomas with invasion of bone: problems and prognosis].
abstract: The cure rate for basal cell carcinomas with the appropriate surgical management is excellent. However, when bony involvement is present the prognosis is adversely effected. Only 0.5% of orofacial basal cell carcinomas in our series had bony involvement. These 12 cases were analysed for recurrence rate. This revealed rates from 60% with primary tumours to 90% for recurrences. According to Kaplan-Meier the expected recurrence rate within 10 years is about 90%. Surprisingly the crucial factor mitigating against a cure is the presence of tumour bony infiltration, rather than the demonstration of tumour at the resection margins.
authors.affiliation: Klinik für Mund-, Kiefer-Gesichtschirurgie, Martin-Luther-Universität, Halle-Wittenberg.
authors.forename: J
authors.initials: J
authors.lastname: Schubert
authors.forename: A
authors.initials: A
authors.lastname: Müller
mesh_terms: D000328:Adult; D000368:Aged; D002280:Basal Cell Carcinoma / Q000401:mortality / Q000473:pathology*; D005153:Facial Neoplasms / Q000401:mortality / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000473:pathology; D009367:Neoplasm Staging; D018365:Neoplasm, Residual / Q000401:mortality / Q000473:pathology; D011379:Prognosis; D012888:Skull Neoplasms / Q000401:mortality / Q000473:pathology*; D016019:Survival Analysis
vernacular_title: Basaliome mit Einbruch in den Knochen: Probleme und Prognose.