title: Emergency stenting of malignant obstruction of the upper airways: long-term follow-up with two types of silicone prostheses.
abstract: We report on 10 patients with severe malignant "mixed-type" obstruction of the proximal trachea or distal trachea plus both main stem bronchi. They had far-advanced inoperable tumors (esophageal cancer in 4 patients, lung cancer in 3, and recurrent laryngeal, uvular, and thyroid cancers in 1 each). Emergency treatment consisted of a dilating bougie maneuver followed by the insertion of a large one-way (4 patients) or Y-shaped (6) silicone prosthesis. Subsequent to the intervention, there was long-lasting clinical improvement. The median survival from stent insertion was 8 months for all patients irrespective of tumor type; it was 5 months for lung carcinoma patients and 8 months for those with esophageal cancer. The results are in accordance with those of other studies using different therapeutic modalities. Stent exchange proved necessary in 5 patients. The main reasons were continuing tumor growth beyond the proximal and distal boundaries and recurrent productive bronchial infection. Patients died of pneumonia (4 patients), pulmonary lymphangitic spread (1), heart failure (2, one of whom also had pneumonia), and fatal hemorrhage (1). As of December 1995, 3 patients were still alive, 2, 5, and 8 months after stent implantation. As evidenced by clinical efficacy and length of palliation, endoscopic placement of silicone-based one-way and bifurcated prostheses in far-advanced tumor of the central airways is technically feasible and ethically justifiable.
authors.affiliation: Department of Otolaryngology, University of Cologne, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Wassermann
authors.forename: H E
authors.initials: HE
authors.lastname: Eckel
authors.forename: O
authors.initials: O
authors.lastname: Michel
authors.forename: R P
authors.initials: RP
authors.lastname: Müller
mesh_terms: D000368:Aged; D001982:Bronchial Diseases / Q000209:etiology / Q000628:therapy*; D003251:Constriction, Pathologic; D004638:Emergency Treatment; D004938:Esophageal Neoplasms / Q000150:complications; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications; D008297:Male; D008875:Middle Aged; D010039:Otorhinolaryngologic Neoplasms / Q000150:complications; D011474:Prosthesis Design; D012189:Retrospective Studies; D012828:Silicones; D015607:Stents; D013964:Thyroid Neoplasms / Q000150:complications; D014135:Tracheal Stenosis / Q000209:etiology / Q000628:therapy*
chemical_list: D012828:Silicones