title: Treatment of intrabony defects by polylactic acid matrix barrier--a one-year follow-up study.
abstract: The present investigation was conducted to evaluate the effect of a polylactic acid-citric acid softened membrane barrier during guided tissue regeneration (GTR) surgery on human intrabony defects. Eighteen patients were treated in the study and 16 patients completed the 1-year follow-up. In all, 27 intrabony defects were treated and clinical soft tissue measurements, including probing depth (PD), probing attachment level (PAL), and recession, were recorded. Results of the investigation demonstrated a significant reduction in PD (3.7 mm), a significant gain in PAL (4.2 mm), and a slight increase in recession (1.2 mm).
authors.affiliation: Northwestern University Dental School, Department of Periodontics, Chicago, Illinois 60611, USA.
authors.forename: E C
authors.initials: EC
authors.lastname: Shen
authors.forename: C L
authors.initials: CL
authors.lastname: Chen
authors.forename: C
authors.initials: C
authors.lastname: Sfeir
authors.forename: A V
authors.initials: AV
authors.lastname: Gargiulo
mesh_terms: D000328:Adult; D000368:Aged; D016301:Alveolar Bone Loss / Q000601:surgery*; D019343:Citric Acid; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D005889:Gingival Recession / Q000601:surgery; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D006801:Humans; D019344:Lactic Acid; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D017622:Periodontal Attachment Loss / Q000601:surgery; D010514:Periodontal Pocket / Q000601:surgery; D011091:Polyesters; D011108:Polymers
chemical_list: D008567:Membranes, Artificial; D011091:Polyesters; D011108:Polymers; D019343:Citric Acid; D019344:Lactic Acid; C033616:poly(lactide)