title: A plasmid-mediated beta-lactamase conferring resistance to cefotaxime in a Salmonella typhimurium clone found in St Petersburg, Russia.
abstract: Four clinical and two environmental isolates of cefotaxime-resistant Salmonella typhimurium strains collected in St Petersburg, Russia, were studied. Molecular typing demonstrated that they constituted a single clone. The isolates expressed a cefotaxime-hydrolysing beta-lactamase with a pl of 8.4. The enzyme was encoded by a 12 kb plasmid which did not hybridize with TEM, SHV or ampC probes.
authors.affiliation: Department of Bacteriology, Hellenic Pasteur Institute, Athens, Greece.
authors.forename: M
authors.initials: M
authors.lastname: Gazouli
authors.forename: S V
authors.initials: SV
authors.lastname: Sidorenko
authors.forename: E
authors.initials: E
authors.lastname: Tzelepi
authors.forename: N S
authors.initials: NS
authors.lastname: Kozlova
authors.forename: D P
authors.initials: DP
authors.lastname: Gladin
authors.forename: L S
authors.initials: LS
authors.lastname: Tzouvelekis
mesh_terms: D002439:Cefotaxime / Q000494:pharmacology*; D002511:Cephalosporins / Q000494:pharmacology*; D010957:Plasmids / Q000235:genetics; D012426:Russia; D012486:Salmonella typhimurium / Q000187:drug effects* / Q000201:enzymology; D001618:beta-Lactamases / Q000187:drug effects* / Q000378:metabolism
chemical_list: D002511:Cephalosporins; D001618:beta-Lactamases; D002439:Cefotaxime