Diffuse pulmonary hemorrhage after fibrinolytic therapy for acute myocardial infarction.
We report a patient with diffuse pulmonary hemorrhage after streptokinase therapy for acute myocardial infarction. Hemoptysis, anemia, fever, jaundice, progressive bilateral pulmonary infiltrates and severe acute respiratory failure were observed. The patient required mechanical ventilation and recovered successfully. An immunological reaction to a highly antigenic agent such as streptokinase is considered in the pathogenesis of this complication.
Masip
J
J
Vecilla
F
F
Páez
J
J
D018893:Bronchoalveolar Lavage; D005343:Fibrinolytic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D005500:Follow-Up Studies; D006469:Hemoptysis / Q000139:chemically induced; D006470:Hemorrhage / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D008171:Lung Diseases / Q000139:chemically induced* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications / Q000188:drug therapy*; D013300:Streptokinase / Q000009:adverse effects* / Q000627:therapeutic use; D015912:Thrombolytic Therapy / Q000009:adverse effects*
D005343:Fibrinolytic Agents; D013300:Streptokinase