title: [Use of software "Aggregate state of the blood" in staged diagnosis and correction of disorders of blood coagulation and rheology].
abstract: The "Aggregate State of the Blood" software was created at the National Research Center of Surgery in 1994. The software is intended for comprehensive assessment of the blood fluidity under different conditions of clotting, rheology, and acid-base balance and shows deviations of the detected values from the norm, predicting the risk of thrombotic and/or hemorrhagic complications. From 1994 to 1996, the program was used in more than 1000 patients subjected to cardiopulmonary bypass surgery with complicated and uneventful peri- and postoperative period. The operations were as follows: heart and liver transplantations (19 and 7 cases), intraaortic balloon counterpulsation (16), extracorporeal detoxication (10), acute myocardial infarction (9), etc. The results were compared with the data recorded in case histories of 255 patients who underwent similar operations in 1991-1994. The results of diagnosis and prediction were commented in the protocol for each case. The conclusions were used for therapy or prevention. The incidence of thrombotic and hemorrhagic complications and the DIC syndrome in 1995-1996, when the new software started to be used, was significantly lower than before. The best clinical results were attained in the patients examined before surgery (n = 92). In this group application of the program (and subsequent preventive treatment) helped improve the adaptive potential of the physiological systems maintaining the blood fluidity. This resulted in a lower postoperative blood loss and a lesser incidence of thrombotic and hemorrhagic complications and the DIC syndrome as against the reference group.
authors.forename: E V
authors.initials: EV
authors.lastname: Roĭtman
authors.forename: I I
authors.initials: II
authors.lastname: Dement'eva
authors.forename: T P
authors.initials: TP
authors.lastname: Ziuliaeva
authors.forename: N I
authors.initials: NI
authors.lastname: Chaus
authors.forename: A A
authors.initials: AA
authors.lastname: Eremenko
authors.forename: Iu M
authors.initials: IuM
authors.lastname: Mikhaĭlov
authors.forename: S F
authors.initials: SF
authors.lastname: Leonova
authors.forename: L V
authors.initials: LV
authors.lastname: Bozh'eva
authors.forename: I V
authors.initials: IV
authors.lastname: Iarygin
authors.forename: V G
authors.initials: VG
authors.lastname: Domnin
authors.forename: I E
authors.initials: IE
authors.lastname: Belianko
mesh_terms: D001777:Blood Coagulation; D001778:Blood Coagulation Disorders / Q000097:blood / Q000175:diagnosis* / Q000628:therapy*; D016063:Blood Loss, Surgical / Q000517:prevention & control; D002315:Cardiopulmonary Bypass / Q000009:adverse effects; D003936:Diagnosis, Computer-Assisted; D018056:Hemorheology / Q000379:methods*; D006801:Humans; D019106:Postoperative Hemorrhage / Q000517:prevention & control; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012984:Software; D013927:Thrombosis / Q000517:prevention & control
vernacular_title: Ispol'zovanie algoritma "Agregatnoe sostoianie krovi" v poétapnoĭ diagnostike i korrektsii narysheniĭ svertovaniia i reologii krovi.