title: [Prophylactic use of Neoton in cardiac failure in patients with myocardial infarction].
abstract: Echocardiography and integral body rheography were made in 174 patients with macrofocal myocardial infarction (MI) to study hemodynamics at six stages of hospital rehabilitation (MI day 1-28). 97 patients received neoton (4 different scheme) in the acute period of MI. Neoton administration was found to prevent progressive left ventricular dilation and emergence of cardiac insufficiency in subacute period of MI, to reduce the risk of cardiac aneurism, recurrence and postinfarction angina. The response to neoton rises with an increase of its dose on the first day of the disease and lessening of the time span from first symptoms of MI and first neoton injection. An optimal scheme of neoton use is proposed.
authors.affiliation: NII of Cardiology, Saint Petersburg.
authors.forename: N B
authors.initials: NB
authors.lastname: Perepech
authors.forename: A O
authors.initials: AO
authors.lastname: Nedoshivin
authors.lastname: Kutuzova A'E
mesh_terms: D000328:Adult; D000368:Aged; D002316:Cardiotonic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004452:Echocardiography; D006333:Heart Failure / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D010725:Phosphocreatine / Q000008:administration & dosage / Q000627:therapeutic use*; D010992:Plethysmography, Impedance; D016896:Treatment Outcome
chemical_list: D002316:Cardiotonic Agents; D010725:Phosphocreatine
vernacular_title: Primenenie Neotona dlia profilaktiki serdechnoí nedostatochnosti u bol'nykh infarktom miokarda.