title: Salivary fluoride levels in overdenture wearers after topical fluoride gel application.
abstract: This study describes salivary fluoride levels after topical fluoride gel application on overdenture abutments. Fluoride levels were evaluated separately for the subjects with normal unstimulated salivary flow rate (n = 16) and for those with a low flow rate (n = 8). One drop of fluoride gel (Karigel-N, Lorvic) was placed in two abutment depressions of the duplicated overdenture, after which unstimulated whole saliva was collected for 30 minutes. Samples for fluoride analysis were taken at 5-minute intervals. Two additional samples were taken at 45 and 60 minutes. Fluoride concentration at the abutment-denture interface (remaining fluoride concentration) was measured at the end of the study. Salivary fluoride concentrations decreased gradually in both groups of subjects, but after 1 hour they remained at a higher level in subjects with low flow rates. Subjects' salivary flow rates correlated negatively with remaining fluoride concentration at the denture-tissue interface. Consequently, mean remaining fluoride concentration was significantly higher in subjects with low flow rate than in their normal counterparts.
authors.affiliation: Department of Prosthodontics, University of Helsinki Institute of Dentistry, Finland.
authors.forename: T O
authors.initials: TO
authors.lastname: Närhi
authors.forename: R L
authors.initials: RL
authors.lastname: Ettinger
authors.forename: J R
authors.initials: JR
authors.lastname: Heilman
authors.forename: J S
authors.initials: JS
authors.lastname: Wefel
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D000044:Dental Abutments; D003828:Denture, Overlay; D005260:Female; D005459:Fluorides / Q000032:analysis*; D005460:Fluorides, Topical / Q000008:administration & dosage*; D005782:Gels; D006801:Humans; D008297:Male; D008875:Middle Aged; D012463:Saliva / Q000737:chemistry* / Q000378:metabolism; D012636:Secretory Rate; D013997:Time Factors
chemical_list: D005460:Fluorides, Topical; D005782:Gels; D005459:Fluorides