Cationic peptides: a new source of antibiotics.
Antimicrobial cationic peptides are an important component of the innate defenses of all species of life. Different peptides may have antibacterial, antiendotoxic, antibiotic-potentiating or antifungal properties, and so they are being developed for use as a novel class of antimicrobial agents and as the basis for making transgenic disease-resistant plants and animals.
Hancock
R E
RE
Department of Microbiology and Immunology, University of British Columbia, Vancouver, Canada.
Lehrer
R
R
D000595:Amino Acid Sequence; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000494:pharmacology*; D023181:Antimicrobial Cationic Peptides; D001798:Blood Proteins / Q000737:chemistry / Q000494:pharmacology*; D003362:Cost-Benefit Analysis; D004268:DNA-Binding Proteins / Q000737:chemistry / Q000494:pharmacology*; D023082:Defensins; D006801:Humans; D007239:Infections / Q000276:immunology; D008969:Molecular Sequence Data; D010456:Peptides, Cyclic / Q000737:chemistry / Q000494:pharmacology*; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry / Q000494:pharmacology*; D019076:Transgenes
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D023181:Antimicrobial Cationic Peptides; D001798:Blood Proteins; D004268:DNA-Binding Proteins; D023082:Defensins; D010456:Peptides, Cyclic; D011506:Proteins; C094880:protegrin-1; C057636:tachyplesin peptide, Tachypleus tridentatus