title: [Quantitative evaluation of the suitability of magnetic resonance sequences for the detection of spinal bone marrow metastases of solid tumors].
abstract: OBJECTIVE
  To compare MR sequences for the examination of the bone marrow of the spine in the detection of skeletal metastases.
  
  
  METHODS
  20 standardised prospective studies of the cervical, thoracic or lumbar spine in patients with known skeletal metastases were evaluated quantitatively. Studies included T1w SE with and without intravenous contrast medium (CM) administration of Gd-DTPA, T2w TSE with and without frequence selective fat saturation (SPIR), opposed phase gradient echo (opGE) with and without intravenous CM administration of Gd-DTPA and T1w SE CM SPIR sequences. The quantitative parameters signal/noise ratio (SNR), contrast/noise ratio (CNR) and contrast were evaluated.
  
  
  RESULTS
  OpGE with contrast showed the best results in SNR, CNR and C. Results were statistically significant. Good SNR and C also was found for T1w SE native. SPIR and T2w sequences were less sensitive.
  
  
  CONCLUSIONS
  OpGE sequences are recommended for the detection of skeletal metastases of the spine.
authors.affiliation: Radiologische Universitätsklinik Bonn.
authors.forename: G
authors.initials: G
authors.lastname: Layer
authors.forename: T
authors.initials: T
authors.lastname: Sommer
authors.forename: M
authors.initials: M
authors.lastname: Busch
authors.forename: H
authors.initials: H
authors.lastname: Schüller
authors.forename: H H
authors.initials: HH
authors.lastname: Schild
mesh_terms: D019046:Bone Marrow Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D003287:Contrast Media; D019786:Gadolinium DTPA; D006801:Humans; D008279:Magnetic Resonance Imaging; D019042:Muscle Neoplasms / Q000175:diagnosis* / Q000473:pathology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013131:Spine
chemical_list: D003287:Contrast Media; D019786:Gadolinium DTPA
vernacular_title: Quantitative Evaluierung der Eignung von Magnetresonanzsequenzen zum Nachweis von Wirbelsäulenmetastasen solider Tumoren.