Methoxyamericanolide B.
The title compound, C16H20O5, was isolated from the gorgonian coral P. americana found in the Caribbean zone of the West Indies. The compound belongs to a well known family of sesquiterpenoid lactones. Its structure features a guaiane skeleton incorporating three types of oxygen functionalities. Thus, the five O atoms that are incorporated in the skeleton form two epoxy groups, a lactone moiety and an ether link. This study assigns the relative stereochemistry at the six chiral centers as 1R, 2R, 4S, 5S, 8R, 10S.
Richardson
P L
PL
Department of Chemistry, University of Puerto Rico, San Juan 00931, USA.
Rodríguez
A D
AD
Boulanger
A
A
Huang
S D
SD
D000818:Animals; D003063:Cnidaria / Q000737:chemistry*; D018360:Crystallography, X-Ray; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry*
D012717:Sesquiterpenes; C111003:methoxyamericanolide B