title: Genetic variation in the east Midlands.
abstract: According to history, the population of the British Isles derives its genepool from a succession of invaders and immigrants. The settlement pattern of these invaders gave rise to a patchwork of genepools, shown in previous genetic surveys. Specimens from 1117 blood donors of regionally subdivided East Midlands (Derbyshire, Nottinghamshire and Leicestershire) were analysed for 18 conventional genetic systems (blood groups, serum proteins and red cell enzymes), according to place of residence. Significant differences exist among the five geographically defined sub-populations, and it is argued that these are derived from the historical settlement of continental European populations in the region, especially the Danes and the Vikings.
authors.affiliation: Department of Human Sciences, Loughborough University, UK.
authors.forename: S S
authors.initials: SS
authors.lastname: Mastana
authors.forename: R J
authors.initials: RJ
authors.lastname: Sokol
mesh_terms: D000704:Analysis of Variance; D000941:Antigens / Q000235:genetics; D001789:Blood Group Antigens / Q000235:genetics / Q000276:immunology; D001798:Blood Proteins / Q000235:genetics; D004912:Erythrocytes / Q000201:enzymology; D014644:Genetic Variation; D015894:Genome, Human; D006801:Humans; D008957:Models, Genetic; D006113:United Kingdom
chemical_list: D000941:Antigens; D001789:Blood Group Antigens; D001798:Blood Proteins