title: [New method of atherosclerotic macular dystrophies treatment].
abstract: The authors analyze the results of treating atherosclerotic maculodystrophies by direct laser phoresis. The method consists in insertion of a collagen infusion system in Tenon's space. Drugs (nicotinic acid or xanthinol nicotinate) are delivered to the posterior compartment of the eye through this system. Then a light guide is inserted in the tube and a 2-min session of low-intensity He-Ne laser exposure is performed at a wavelength of 630 nm, and 10 mWt/cm2 flow power density (7 to 10 sessions per course). Clinical studies showed that vision acuity increased by an average of 0.08 diopters, or by 40% of the initial level, in 72% of cases. The peripheral visual field extended by an average of 51.4 degrees for 8 meridians in 95% of patients. The index of critical frequency of flashings fusing and the frequency-contrast characteristics improved in 85% of cases. The rheography improved by 34.5% of the initial level. A stable improvement was observed for 12 months after a course of direct laser phoresis in 97.5% of patients. Hence, the new method is simple and recommended for the treatment of atherosclerotic maculodystrophies.
authors.forename: S N
authors.initials: SN
authors.lastname: Basinskiĭ
authors.forename: V N
authors.initials: VN
authors.lastname: Krasnogorskaia
mesh_terms: D001161:Arteriosclerosis / Q000150:complications* / Q000503:physiopathology; D003094:Collagen; D005500:Follow-Up Studies; D006801:Humans; D007263:Infusions, Parenteral; D007834:Lasers; D008268:Macular Degeneration / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D008875:Middle Aged; D009525:Niacin / Q000008:administration & dosage*; D017893:Photopheresis / Q000379:methods*; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000008:administration & dosage*; D014792:Visual Acuity / Q000502:physiology; D014794:Visual Fields / Q000502:physiology; D014971:Xanthinol Niacinate / Q000008:administration & dosage*
chemical_list: D014665:Vasodilator Agents; D009525:Niacin; D014971:Xanthinol Niacinate; D003094:Collagen
vernacular_title: Novyĭ metod lecheniia ateroskleroticheskikh makulodistrofiĭ.