title: Enteroaggregative, Shiga toxin-producing Escherichia coli O111:H2 associated with an outbreak of hemolytic-uremic syndrome.
abstract: Shiga toxin-producing Escherichia coli O111:H2 strains from an outbreak of hemolytic-uremic syndrome showed aggregative adhesion to HEp-2 cells and harbored large plasmids which hybridized with the enteroaggregative E. coli probe PCVD432. These strains present a novel combination of virulence factors and might be as pathogenic to humans as the classic enterohemorrhagic E. coli.
authors.affiliation: Laboratorio di Medicina Veterinaria, Istituto Superiore di Sanità, Rome, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Morabito
authors.forename: H
authors.initials: H
authors.lastname: Karch
authors.forename: P
authors.initials: P
authors.lastname: Mariani-Kurkdjian
authors.forename: H
authors.initials: H
authors.lastname: Schmidt
authors.forename: F
authors.initials: F
authors.lastname: Minelli
authors.forename: E
authors.initials: E
authors.lastname: Bingen
authors.forename: A
authors.initials: A
authors.lastname: Caprioli
mesh_terms: D001422:Bacterial Adhesion; D001427:Bacterial Toxins / Q000096:biosynthesis*; D003090:Coliphages / Q000235:genetics / Q000502:physiology; D004196:Disease Outbreaks; D004926:Escherichia coli / Q000235:genetics / Q000472:pathogenicity*; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology*; D006463:Hemolytic-Uremic Syndrome / Q000453:epidemiology / Q000382:microbiology*; D006801:Humans; D010957:Plasmids; D022603:Shiga Toxins; D014407:Tumor Cells, Cultured; D014774:Virulence
chemical_list: D001427:Bacterial Toxins; D022603:Shiga Toxins