Intermediate filaments and their associated proteins: multiple dynamic personalities.
A fusion of mouse and human genetics has now proven that intermediate filaments form a flexible scaffold essential for structuring cytoplasm in a variety of cell contexts. In some cases, the formation of this scaffold is achieved through a newly identified family of intermediate-filament-associated proteins that form cross-bridges between intermediate filaments and other cytoskeletal elements, including actin and microtubules.
Houseweart
M K
MK
Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla 92093, USA.
Cleveland
D W
DW
D000818:Animals; D006801:Humans; D007381:Intermediate Filament Proteins / Q000502:physiology*; D007382:Intermediate Filaments / Q000502:physiology*; D051379:Mice
D007381:Intermediate Filament Proteins