Cerebral metastasis in patients with uterine cervical cancer.
We report on eight patients who developed brain metastases following uterine cervical cancer. The mean interval between diagnosis of the primary cancer and diagnosis of the brain metastasis was 28.4 months (range: 6.1-61.8 months). Nausea and vomiting due to increased intracranial pressure were the most frequent symptoms. Surgical excision of the brain lesions, followed by postoperative radiotherapy, was performed in three patients. The other five patients received only cranial radiotherapy. When the metastatic brain lesions were detected, other distant metastatic lesions were confirmed at the same time in five patients. The median survival time after diagnosis of the brain metastases was only 3.0 months.
Ikeda
S
S
Department of Gynecology, National Cancer Center Hospital, Tokyo, Japan.
Yamada
T
T
Katsumata
N
N
Hida
K
K
Tanemura
K
K
Tsunematu
R
R
Ohmi
K
K
Sonoda
T
T
Ikeda
H
H
Nomura
K
K
D000230:Adenocarcinoma / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D000328:Adult; D000368:Aged; D001932:Brain Neoplasms / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D002277:Carcinoma / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000532:radiotherapy / Q000556:secondary* / Q000601:surgery; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008875:Middle Aged; D011379:Prognosis; D015173:Supratentorial Neoplasms / Q000532:radiotherapy / Q000556:secondary / Q000601:surgery; D016019:Survival Analysis; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery