title: [Long-term outcome of 72 patients surgically treated for stage II non-small cell bronchial cancer, between 1982 and 1989].
abstract: We report a 72 patients trial, who had surgical treatments for non small cell lung cancer, stage II (T1N1, T2N1). In our retrospective study, the overall 5-years survival is 44%, with a 24-month median survival. 45% of the patients have recurrence mainly due to distant metastasis. State II appears to be an heterogeneous group. As shown in other studies, the presence of hilar nodes (N1H) seems to be linked with a pejorative outcome. In our series, the survival associated with Lobar N1 (N1L) disease is the same as the survival of Hilar N1 disease, but the initial sites of recurrence differ. The interest of a postchirurgical treatment is controversial. The postoperative radiotherapy reduces the local recurrence without increasing the survival. The chemotherapy treatment is debatable and several studies are under way. We reviewed the different causes of death. The appearance of second cancer in the cured patients is very frequent.
authors.affiliation: Service de Pneumologie, Centre Hospitalo-Universitaire Lyon-Sud, Pierre-Bénite.
authors.forename: J
authors.initials: J
authors.lastname: Brunel-Crova
authors.forename: B
authors.initials: B
authors.lastname: Guibert
authors.forename: P
authors.initials: P
authors.lastname: Mulsant
authors.forename: P J
authors.initials: PJ
authors.lastname: Souquet
authors.forename: L
authors.initials: L
authors.lastname: Gérinière
authors.forename: P
authors.initials: P
authors.lastname: Bombaron
authors.forename: J P
authors.initials: JP
authors.lastname: Bernard
mesh_terms: D000328:Adult; D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D002423:Cause of Death; D017024:Chemotherapy, Adjuvant; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000601:surgery*; D008198:Lymph Nodes / Q000473:pathology; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D016609:Neoplasms, Second Primary / Q000473:pathology; D011013:Pneumonectomy; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome
vernacular_title: Devenir à long terme de 72 patients opérés d'un cancer bronchique non à petites cellules, de stade II, entre 1982 et 1989.