title: NSAIDs: a critical appraisal.
abstract: In this issue, a case history is presented illustrating a serious side-effect of a non-steroidal anti-inflammatory drug (NSAID). It gives rise to a critical re-appraisal of NSAIDs.
authors.affiliation: Department of Rheumatology and Clinical Immunology, University Hospital Utrecht, Netherlands.
authors.forename: J W
authors.initials: JW
authors.lastname: Jacobs
authors.forename: J W
authors.initials: JW
authors.lastname: Bijlsma
mesh_terms: D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D005753:Gastric Mucosa / Q000187:drug effects; D005767:Gastrointestinal Diseases / Q000139:chemically induced* / Q000201:enzymology / Q000517:prevention & control; D006801:Humans; D007413:Intestinal Mucosa / Q000187:drug effects; D011379:Prognosis; D011451:Prostaglandin-Endoperoxide Synthases / Q000187:drug effects* / Q000378:metabolism
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D011451:Prostaglandin-Endoperoxide Synthases