title: Molecular evidence that a distinct Vibrio cholerae O1 biotype El Tor strain in Calcutta may have spread to the African continent.
abstract: We present molecular evidence that a distinct genotype of Vibrio cholerae O1 which appeared in Calcutta, India, in September 1993 and which is characterized by a unique ribotype that is not found in the standardized ribotyping scheme of V. cholerae and that shows a specific pulsed-field gel electrophoresis profile may have spread to the west African country of Guinea-Bissau where it was responsible for an epidemic of cholera which began in October 1994 and continued into 1996.
authors.affiliation: Institute of Microbial Technology, Chandigarh, India.
authors.forename: C
authors.initials: C
authors.lastname: Sharma
authors.forename: A
authors.initials: A
authors.lastname: Ghosh
authors.forename: A
authors.initials: A
authors.lastname: Dalsgaard
authors.forename: A
authors.initials: A
authors.lastname: Forslund
authors.forename: R K
authors.initials: RK
authors.lastname: Ghosh
authors.forename: S K
authors.initials: SK
authors.lastname: Bhattacharya
authors.forename: G B
authors.initials: GB
authors.lastname: Nair
mesh_terms: D015373:Bacterial Typing Techniques; D002771:Cholera / Q000453:epidemiology* / Q000382:microbiology*; D004196:Disease Outbreaks; D016521:Electrophoresis, Gel, Pulsed-Field; D006169:Guinea-Bissau / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D017720:Molecular Epidemiology; D015347:RNA Probes; D012329:RNA, Bacterial / Q000235:genetics; D012335:RNA, Ribosomal / Q000235:genetics; D012703:Serotyping; D014734:Vibrio cholerae / Q000145:classification* / Q000235:genetics; D012407:rRNA Operon
chemical_list: D015347:RNA Probes; D012329:RNA, Bacterial; D012335:RNA, Ribosomal