Ultraviolet radiation and skin carcinogenesis.
The incidence of skin cancer has increased over the last 30 years. Although the role of ultraviolet radiation in human skin carcinogenesis has been supported by a wealth of epidemiological data, the mechanisms by which it leads to skin cancer are still poorly understood. This article reviews recent developments in understanding of the epidemiology and molecular biology of skin carcinogenesis.
Quinn
A G
AG
Centre for Cutaneous Research, St Bartholomew's, London.
D002280:Basal Cell Carcinoma / Q000209:etiology* / Q000235:genetics; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000235:genetics; D004249:DNA Damage; D004260:DNA Repair; D006801:Humans; D015994:Incidence; D008545:Melanoma / Q000209:etiology* / Q000235:genetics; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors; D012878:Skin Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000235:genetics; D014466:Ultraviolet Rays / Q000009:adverse effects*; D006113:United Kingdom / Q000453:epidemiology