Analysis of DNA adducts by capillary methods coupled to mass spectrometry: a perspective.
The analysis of DNA adducts, important molecular biomarkers indicative of potential cellular damage by covalent attachment to DNA, is discussed. The paper focusses on a discussion of the current status in the analysis of DNA adducts via the use of capillary high-performance liquid chromatographic and capillary electrophoretic methods coupled to tandem mass spectrometry.
Apruzzese
W A
WA
Department of Chemistry, Northeastern University, Boston, MA 02115, USA.
Vouros
P
P
D000818:Animals; D018736:DNA Adducts / Q000032:analysis*; D019075:Electrophoresis, Capillary; D006801:Humans; D013058:Mass Spectrometry
D018736:DNA Adducts