title: Extraskeletal osteosarcomas in dogs: a retrospective study of 169 cases (1986-1996).
abstract: Extraskeletal osteosarcomas (EOSs) are rare tumors that arise in various soft-tissue sites (e.g., gastrointestinal tract, subcutaneous tissue, spleen, liver, skin, kidney, urinary bladder, muscle, thyroid gland, eye, and mammary glands). Soft-tissue osteosarcomas (STOs) occur in older dogs with no sex predilection; beagles and rottweilers are at higher risk. Mammary gland osteosarcomas (MGOs) occur in older females; mixed-breed dogs, German shepherd dogs, and miniature poodles are at higher risk. The median survival time for cases with STO was 26 days, and the major cause of death was local recurrence (92%). The median survival time for cases with MGO was 90 days, and the major cause of death was pulmonary metastasis (62.5%).
authors.affiliation: Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia 19104-6010, USA.
authors.forename: A
authors.initials: A
authors.lastname: Langenbach
authors.forename: M A
authors.initials: MA
authors.lastname: Anderson
authors.forename: D M
authors.initials: DM
authors.lastname: Dambach
authors.forename: K U
authors.initials: KU
authors.lastname: Sorenmo
authors.forename: F D
authors.initials: FD
authors.lastname: Shofer
mesh_terms: D000818:Animals; D001706:Biopsy / Q000662:veterinary; D016001:Confidence Intervals; D004283:Dog Diseases / Q000453:epidemiology / Q000473:pathology*; D004285:Dogs; D005260:Female; D008297:Male; D015674:Mammary Neoplasms, Animal / Q000453:epidemiology / Q000473:pathology*; D016017:Odds Ratio; D012516:Osteosarcoma / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary*; D011379:Prognosis; D012189:Retrospective Studies; D012983:Soft Tissue Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000662:veterinary*; D016019:Survival Analysis