title: Correction of B1 inhomogeneities using echo-planar imaging of water.
abstract: Reliable interpretation of the MR signal intensity over the FOV of an image must consider the spatial heterogeneity of instrumental sensitivity. A major source of such variation is the nonuniformity of the B1 magnetic field of the radiofrequency coil. This heterogeneity can be minimized by coil design but is exaggerated by surface coils, which are used to maximize the signal-to-noise ratio for some applications. This paper describes a rapid method for mapping the B1 field over the sample of interest, using 1H echo-planar imaging, to correct for B1 distortions. The method applies to 1H imaging and has been extended to non-1H imaging by using dual-frequency coils in which the B1 distributions are matched for the 1H frequency and the frequency of interest. The approach is demonstrated in phantoms, animals, and humans and for sodium imaging.
authors.affiliation: MR Research Center, Department of Radiology, University of Pittsburgh Medical Center, Pennsylvania, USA.
authors.forename: K R
authors.initials: KR
authors.lastname: Thulborn
authors.forename: F E
authors.initials: FE
authors.lastname: Boada
authors.forename: G X
authors.initials: GX
authors.lastname: Shen
authors.forename: J D
authors.initials: JD
authors.lastname: Christensen
authors.forename: T G
authors.initials: TG
authors.lastname: Reese
mesh_terms: D000465:Algorithms; D000818:Animals; D016477:Artifacts; D001834:Body Water / Q000737:chemistry*; D001921:Brain / Q000033:anatomy & histology; D003903:Deuterium; D017352:Echo-Planar Imaging / Q000295:instrumentation / Q000379:methods*; D004867:Equipment Design; D005583:Fourier Analysis; D006801:Humans; D006859:Hydrogen; D007089:Image Enhancement / Q000379:methods*; D008280:Magnetics; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D011522:Protons; D015203:Reproducibility of Results; D012964:Sodium; D012965:Sodium Chloride; D013552:Swine; D013556:Swine, Miniature
chemical_list: D011522:Protons; D012965:Sodium Chloride; D006859:Hydrogen; D012964:Sodium; D003903:Deuterium