[The unmasking of secondary adrenal insufficiency and central diabetes insipidus by a highly febrile acute Hantaan virus infection].
METHODS
A 32-year-old obese patient was admitted to our hospital as an emergency with very severe abdominal pain. Routine examinations initially failed to establish a diagnosis. The patient then went on to develop a high fever that was associated with polydipsia and polyuria. Serological studies revealed an acute infection with the Hantaan virus. Laboratory investigations showed hypofunction of the anterior and posterior lobes of the pituitary, with complete absence of ACTH, which was caused by two germinomas located intracranially.


CONCLUSIONS
The clinical symptoms had thus been the result of acute secondary insufficiency of the adrenal cortex, which was unmasked by the acute, highly febrile Hantaan viral infection.
Schröder
S
S
Abteilung für Endokrinologie und Stoffwechselerkrankungen, Medizinische Universitätsklinik und Poliklinik Tübingen.
Dilger
J
J
Weiss
E M
EM
Seif
F J
FJ
D000309:Adrenal Insufficiency / Q000150:complications / Q000175:diagnosis* / Q000209:etiology; D000328:Adult; D003919:Diabetes Insipidus / Q000150:complications / Q000175:diagnosis* / Q000209:etiology; D003937:Diagnosis, Differential; D005334:Fever / Q000821:virology*; D018237:Germinoma / Q000150:complications / Q000175:diagnosis*; D006480:Hemorrhagic Fever with Renal Syndrome / Q000150:complications*; D006801:Humans; D008297:Male; D010911:Pituitary Neoplasms / Q000150:complications / Q000175:diagnosis*
Demaskierung einer sekundären Nebennierenrindeninsuffizienz und eines Diabetes insipidus centralis durch eine hochfieberhafte akute Hantaan-Virus-Infektion.