[Clinical study of MRSA carrier in sputum].
We studied the clinical aspects of 25 patients (17 male, 8 female, median age 79.4 y.o.) whom MRSA was colonized in sputum from 1989 January to 1994 December. Main underlying diseases were 16 chronic bronchitis and 15 Cerebrovascular damage. Nineteen cases (76%) had catheters, for example 15 urinary tract catheters and 8 nasogastric tube. Twenty-two cases (88%) used previous antimicrobial agent. Fifteen cases (60%) were dead during previous period, and that 14 cases were dead because of respiratory failure within a year after MRSA was colonized in sputum. Nine cases (36%) were able to remove MRSA in sputum, but mortality rate was not different whether MRSA disappear or continue, MIC50 against MRSA (19 strains) were minocycline 12.5 micrograms/ml, arbekacin 6.25 micrograms/ml, vancomycin 0.78 microgram/ml and 16 cases (84.2%) were coagulase type II.
Watanabe
H
H
Department of Respiratory Medicine, National Kawatana Hospital.
Yoshimine
H
H
Tanaka
H
H
Suenaga
N
N
Watanabe
K
K
Rikitomi
N
N
Nagatake
T
T
D000368:Aged; D001991:Bronchitis / Q000382:microbiology; D002353:Carrier State / Q000382:microbiology*; D002561:Cerebrovascular Disorders / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008712:Methicillin / Q000494:pharmacology*; D013183:Sputum / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000302:isolation & purification
D008712:Methicillin