[Current views on surgical treatment of non-small cell lung neoplasms with metastasis to the central nervous system].
Non-small cell lung cancer is the most frequently encountered malignant neoplasm. Brain metastases occur in about 30% of patients with NSCLC The recent data from Poland indicate that there were about 6000 patients with NSCLC and brain metastasis in the year 1993. The first symptoms in those patients are usually of neurological nature, because brain metastases have high dynamics of growth and accompanying brain oedema accelerates increase of intracranial hypertension. Although the surgical treatment of NSCLC with brain metastases has been known for 50 years there is still controversy over indications for such treatment and possibility of improvement in results by combining surgery with other methods of treatment. There is good evidence in literature on the surgical treatment of lung cancer and synchronous brain metastasis. In some papers the results of treatment of many hundreds of patients are presented. They show, that thoracic and neurological surgery operations coordinated in time provide a chance to extend the survival time of the majority of patients, and enable even 5-year survival in up to 20% of patients. Polish experience on this subject resulted in only a few publications. Majority of those papers come from neurosurgical centres related to the results of treatment of brain metastases. Patients with single brain metastasis and a resectable primary lung tumour have the best prognosis for radical treatment. Presented study suggests that it is still worth undertaking the combined neurosurgical and thoraco-surgical treatment in patients with NSCLC and brain metastasis.
Furmanik
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Katedry i Kliniki Chirurgii Klatki Piersiowej i Serca Akademii Medycznej w Lublinie.
Sawicki
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D002289:Carcinoma, Non-Small-Cell Lung / Q000556:secondary* / Q000601:surgery*; D016543:Central Nervous System Neoplasms / Q000556:secondary* / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000601:surgery*
Współczesne poglady na leczenie chirurgiczne niedrobnokomórkowego raka płuca z przerzutem(ami) do ośrodkowego układu nerwowego.