title: Improved resolution and signal-to-noise ratio in MRI via enhanced signal digitization.
abstract: The high frequency k-space data in magnetic resonance imaging is often poorly reproduced due to the finite dynamic range of an analog-to-digital converter. The magnitude of this digitization error can equal and even exceed the magnitude of the thermal noise. Under such conditions, attempts to increase image signal-to-noise ratio via signal averaging meet with diminishing success. Because the relative size of the digitization error increases at higher spatial frequencies, a reduction in image resolution is incurred as well. By adjusting the level of the analog signal sampled by the analog-to-digital converter during the course of an imaging experiment, the magnitude of the digitization artifact can be greatly reduced. The results of simulations and imaging experiments are presented which demonstrate that this strategy improves both the signal-to-noise ratio and resolution of magnetic resonance images.
authors.affiliation: Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6100, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Elliott
authors.forename: E K
authors.initials: EK
authors.lastname: Insko
authors.forename: R L
authors.initials: RL
authors.lastname: Greenman
authors.forename: J S
authors.initials: JS
authors.lastname: Leigh
mesh_terms: D016477:Artifacts; D003198:Computer Simulation; D005583:Fourier Analysis; D007089:Image Enhancement; D008279:Magnetic Resonance Imaging / Q000379:methods*