title: [Seroprevalence of cytomegalovirus and Toxoplasma gondii in healthy subjects under 30 years old in Santiago, Chile].
abstract: BACKGROUND
  Infections by Cytomegalovirus and Toxoplasma gondii are endemic in Chile and only a low proportion of infected individuals have clinical manifestations.
  
  
  OBJECTIVE
  To study the prevalence of infection by Cytomegalovirus and Toxoplasma gondii in Chile.
  
  
  METHODS
  The prevalence of IgG antibodies against Cytomegalovirus and Toxoplasma gondii were studied in 560 subjects under 30 years old, using an ELISA technique. Age, socioeconomic level, breast feeding, assistance to nurseries and number of family members were considered as risk factors for these infections.
  
  
  RESULTS
  Infection by Cytomegalovirus had a global prevalence of 60%. It showed an epidemiological pattern of late acquisition in high socioeconomic levels and a pattern of early infection in medium and low socioeconomic levels. Eighty to 90% of sera were positive for the infection in adult subjects of the three socioeconomic levels. There was a positive correlation between the duration of breast feeding and the frequency of Cytomegalovirus infection. Infection by Toxoplasma gondii had a global prevalence of 24.6%. The rates of susceptible individuals were 80 and 50% in high and medium-low socioeconomic levels respectively.
  
  
  CONCLUSIONS
  The knowledge about the frequency of these infections in high risk populations such as women during their reproductive years and immunodepressed individuals, will allow the implementation of preventive measures.
authors.affiliation: Departamento de Pediatría, Facultad de Medicina, Universidad Católica de Chile.
authors.forename: K
authors.initials: K
authors.lastname: Abarca
authors.forename: P A
authors.initials: PA
authors.lastname: Vial
authors.forename: J
authors.initials: J
authors.lastname: Zamorano
authors.forename: C
authors.initials: C
authors.lastname: Paris
authors.forename: M
authors.initials: M
authors.lastname: Ferrés
authors.forename: L
authors.initials: L
authors.lastname: Villarroel
authors.forename: C
authors.initials: C
authors.lastname: Ferreccio
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000097:blood*; D000914:Antibodies, Viral / Q000097:blood*; D016009:Chi-Square Distribution; D002648:Child; D002675:Child, Preschool; D002677:Chile / Q000453:epidemiology; D003587:Cytomegalovirus / Q000276:immunology*; D003586:Cytomegalovirus Infections / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000453:epidemiology*
chemical_list: D000913:Antibodies, Protozoan; D000914:Antibodies, Viral
vernacular_title: Seroprevalencia de citomegalovirus y Toxoplasma gondii en población sana menor de 30 años, en Santiago de Chile.