McAB 300 antibody against calbindin D-28K is a glial marker in the teleost brain.
The monoclonal antibody McAB 300 against calbindin D-28 k demonstrated an immunostaining pattern in the teleost brain completely different to those obtained in other classes of vertebrates, or after using in the teleost brain other monoclonal and polyclonal antibodies raised against the same protein. Although calbindin D-28k is considered a neuronal marker, McAB 300 specifically stained glial cells throughout the brains of teleosts, with the only exception of some retinal amacrine and horizontal cells.
Alonso
J R
JR
Departamento de Biología Celular y Patología, Universidad de Salamanca, Spain.
García-Ojeda
E
E
Weruaga
E
E
Briñón
J G
JG
Arévalo
R
R
Celio
M R
MR
Aijón
J
J
D000818:Animals; D000911:Antibodies, Monoclonal; D015415:Biomarkers; D001923:Brain Chemistry / Q000502:physiology*; D064026:Calbindins; D005399:Fishes / Q000378:metabolism*; D005904:Glial Fibrillary Acidic Protein / Q000378:metabolism; D007150:Immunohistochemistry; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D009457:Neuroglia / Q000378:metabolism*; D017686:Oncorhynchus mykiss / Q000378:metabolism*; D016612:Paraffin Embedding; D051381:Rats; D017208:Rats, Wistar; D064030:S100 Calcium Binding Protein G / Q000378:metabolism*; D014746:Vimentin / Q000378:metabolism
D000911:Antibodies, Monoclonal; D015415:Biomarkers; D064026:Calbindins; D005904:Glial Fibrillary Acidic Protein; D009419:Nerve Tissue Proteins; D064030:S100 Calcium Binding Protein G; D014746:Vimentin