title: [Clinical importance of antinuclear antibodies].
abstract: Determination of antinuclear antibodies in the sera of patients with multisystem connective tissue disease has a long clinical application. In the review article authors report on their clinical significance and describe the types of antinuclear antibodies; anti-DNA antibodies, antihistone antibodies, anti-RNA-protein complexes and other antinuclear antibodies. The methods of laboratory determination of antibody types are discussed as well as their application in the diagnosis of autoimmune and multisystem-rheumatic diseases.
authors.affiliation: Zavod za klinicku imunologiju i reumatologiju, Klinika za unutrasnje bolesti Medicinskog fakulteta i Klinickog bolnickog centra Zagreb.
authors.forename: N
authors.initials: N
authors.lastname: Dabelić
authors.forename: N
authors.initials: N
authors.lastname: Cikes
mesh_terms: D000974:Antibodies, Antinuclear / Q000032:analysis*; D001327:Autoimmune Diseases / Q000175:diagnosis*; D003240:Connective Tissue Diseases / Q000175:diagnosis*; D006801:Humans
chemical_list: D000974:Antibodies, Antinuclear
vernacular_title: Klinicko znacenje antinuklearnih protutijela.