title: Mortality and morbidity among patients who undergo combined valve and coronary artery bypass surgery: early and late results.
abstract: OBJECTIVE
  To describe mortality and morbidity early and late after combined valve surgery and coronary artery bypass grafting (CABG) as compared with CABG alone.
  
  
  METHODS
  All patients from western Sweden in whom CABG in combination with valve surgery or CABG alone was carried out in 1988-1991.
  
  
  RESULTS
  Among 2116 patients who underwent CABG, 35 (2%) had this combined with mitral valve surgery and 134 (6%) had this combined with aortic valve surgery, whereas the remaining 92% underwent CABG alone. Patients who underwent combined valve surgery and CABG were older, included more women and had a higher prevalence of previous congestive heart failure and renal dysfunction but on the other hand a less severe coronary artery disease. Among patients who underwent mitral valve surgery in combination with CABG the mortality over the subsequent 5 years was 45%). The corresponding figure for patients who underwent aortic valve surgery in combination with CABG was 24%. Both were higher than for CABG alone (14%; P < 0.0001 and P = 0.003, respectively). In a stepwise multiple regression model mitral valve surgery in combination with CABG was found to be an independent significant predictor for death but aortic valve surgery in combination with CABG was not. Among patients who underwent mitral valve surgery in combination with CABG and were discharged alive from hospital 77% were rehospitalized during the 2 years following the operation as compared with 48% among patients who underwent aortic valve surgery in combination with CABG and 43% among patients with CABG alone. Multiple regression identified mitral valve surgery in combination with CABG as a significant independent predictor for rehospitalization but not aortic valve plus CABG.
  
  
  CONCLUSIONS
  Among patients who either underwent CABG in combination with mitral valve surgery or aortic valve surgery or CABG alone, mitral valve surgery in combination with CABG was independently associated with death and rehospitalization, but the combination of aortic valve surgery and CABG was not.
authors.affiliation: Division of Cardiology, Sahlgrenska University Hospital, Göteborg, Sweden.
authors.forename: J
authors.initials: J
authors.lastname: Herlitz
authors.forename: G
authors.initials: G
authors.lastname: Brandrup-Wognsen
authors.forename: K
authors.initials: K
authors.lastname: Caidahl
authors.forename: M
authors.initials: M
authors.lastname: Haglid
authors.forename: B W
authors.initials: BW
authors.lastname: Karlsson
authors.forename: T
authors.initials: T
authors.lastname: Karlsson
authors.forename: P
authors.initials: P
authors.lastname: Albertsson
authors.forename: B
authors.initials: B
authors.lastname: Lindelöw
mesh_terms: D000368:Aged; D001026:Coronary Artery Bypass / Q000401:mortality*; D003327:Coronary Disease / Q000150:complications / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006349:Heart Valve Diseases / Q000150:complications / Q000601:surgery; D019918:Heart Valve Prosthesis Implantation / Q000401:mortality*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D011379:Prognosis; D012086:Reoperation; D012189:Retrospective Studies; D015996:Survival Rate; D013548:Sweden / Q000453:epidemiology