Medical and interventional therapy of coronary artery disease in women.
Coronary artery disease is the leading cause of death in women, and the importance of this condition is not generally appreciated. Few studies are available that investigate the response of women to the various therapeutic agents that are used in this disease. Those that are available suggest that risk factor reduction and estrogen replacement therapy are important, and that aspirin and vitamin E may be helpful in primary prevention in women. After myocardial infarction, thrombolytics and percutaneous transluminal coronary angioplasty reduce mortality and beta-adrenergic blocking agents and ACE inhibitors are valuable. Elective percutaneous transluminal coronary angioplasty appears to have similar success rates in men and women. In order to most effectively treat women with coronary artery disease, studies on their response to therapy are needed.
Krause
A
A
Cardiology section, LSU School of Medicine, Shreveport, La., USA.
Hanley
H G
HG
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D015906:Angioplasty, Balloon, Coronary; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D002423:Cause of Death; D003327:Coronary Disease / Q000209:etiology / Q000401:mortality / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000209:etiology / Q000401:mortality / Q000628:therapy; D012727:Sex Characteristics; D015912:Thrombolytic Therapy; D016896:Treatment Outcome
D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors