[The effect of sodium ions in vitro on the hemostatic balance of whole blood in patients with ischemic heart disease and hypercoagulation].
Effects were studied of Na+ ions on parameters characterizing phases of blood coagulation as was the state of the fibrinolysis system in 22 patients with ischemic heart disease presenting with hypercoagulation, using a laboratory model of a new apparatus "Koaguloskop TS", its prototype being electrocoagulograph. It has been proved for the first time that Na+ ions are involved in the reduction of the blood coagulative potential and clot density, increase in the power of the anticoagulation system, quick activation of the processes of fibrinolysis and efficient lysis of the clot. A real idea of degree of hemostasis destruction permit obtaining values reflecting the result of the whole blood physical and chemical reaction of coagulation (or fibrinolysis) as a quantity of the substance produced and its density in each phase.
Tolstopiatov
S M
SM
D001778:Blood Coagulation Disorders / Q000097:blood*; D001780:Blood Coagulation Tests / Q000295:instrumentation; D003018:Clot Retraction; D006487:Hemostasis / Q000187:drug effects*; D006801:Humans; D008838:Microcomputers; D017202:Myocardial Ischemia / Q000097:blood*; D012964:Sodium / Q000494:pharmacology*; D014680:Veins
D012964:Sodium
Vliianie ionov natriia in vitro na gemostaticheskiĭ balans tsel'noĭ krovi u bol'nykh ishemicheskoĭ bolezn'iu serdtsa s giperkoaguliatsieĭ.