Serum interleukin-2 and interleukin-6 levels in iron deficiency anemia.
The aim of this study was to investigate the serum levels of interleukin-2 (IL-2) and interleukin-6 (IL-6) in children with iron deficiency anemia before and after iron supplementation. Twenty-five children with iron deficiency anemia 6 months to 3 years of age were included in the study. Ten age- and sex-matched healthy children constituted the control group. In the iron-deficiency group the production of IL-2 was found to be significantly lower than that in controls and became normal after iron supplementation (P < .001). But there was no difference in serum levels of IL-6 in iron deficiency anemia before and after iron supplementation (P > .05).
Sipahi
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Dr. Sami Ulus Children's Medical Center, Department of Pediatric Hematology, Ankara University, Turkey.
Akar
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Eğin
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Cin
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D018798:Anemia, Iron-Deficiency / Q000097:blood* / Q000188:drug therapy / Q000276:immunology*; D002675:Child, Preschool; D019587:Dietary Supplements; D005293:Ferritins / Q000097:blood; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007223:Infant; D007376:Interleukin-2 / Q000097:blood*; D015850:Interleukin-6 / Q000097:blood*; D007501:Iron / Q000097:blood / Q000627:therapeutic use*; D012016:Reference Values; D014168:Transferrin / Q000378:metabolism
D006454:Hemoglobins; D007376:Interleukin-2; D015850:Interleukin-6; D014168:Transferrin; D005293:Ferritins; D007501:Iron