Calretinin-immunoreactive terminals make synapses on calbindin D28k-immunoreactive neurons in the lateral nucleus of the human amygdala.
A double-labeling immunohistochemical procedure and correlated light and electron microscopy were used to examine if calretinin-immunoreactive terminals make synapses on calbindin D28k-positive cells. In the lateral nucleus of the human amygdala, calretinin terminals make symmetric-like synapses on the somata and proximal dendrites of calbindin D28k-labeled cells. Our data provide the first evidence that neurons which contain two different calcium-binding proteins form synaptic contacts with each other in the human amygdala.
Sorvari
H
H
Department of Neuroscience and Neurology, University of Kuopio, P.O. Box 1627, FIN-70211 Kuopio, Finland.
Miettinen
R
R
Soininen
H
H
Paljärvi
L
L
Karkola
K
K
Pitkänen
A
A
D000328:Adult; D000368:Aged; D000679:Amygdala / Q000737:chemistry*; D000918:Antibody Specificity; D064092:Calbindin 1; D064032:Calbindin 2; D064026:Calbindins; D005260:Female; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D007395:Interneurons / Q000737:chemistry / Q000648:ultrastructure; D008297:Male; D016253:Microscopy, Immunoelectron; D008875:Middle Aged; D009419:Nerve Tissue Proteins / Q000032:analysis / Q000276:immunology*; D064030:S100 Calcium Binding Protein G / Q000032:analysis / Q000276:immunology*; D013569:Synapses / Q000737:chemistry* / Q000648:ultrastructure
C576498:CALB1 protein, human; C576764:CALB2 protein, human; D064092:Calbindin 1; D064032:Calbindin 2; D064026:Calbindins; D009419:Nerve Tissue Proteins; D064030:S100 Calcium Binding Protein G