title: A model of radiostrontium transfer in dairy goats based on calcium metabolism.
abstract: A model for the transfer of radiostrontium (90Sr) in dairy goats is presented. The novel feature of the model is that it is based on the current understanding of Ca metabolism and assumes that the transfer of radiostrontium is driven by Ca transfer. Previously published models of radiostrontium transfer in animals have ignored the influence of Ca metabolism. Unknown model parameters were obtained by fitting the model to data from a study of radiostrontium and Ca transfer in goats. The model accounted for 95 and 97% of the observed variation in the data for Ca (n = 22) and radiostrontium (n = 43), respectively. Unlike previously reported models, the model presented here could be applied to simulate the effect of additional dietary Ca as a countermeasure to the contamination of milk by radiostrontium under different circumstances.
authors.affiliation: Department of Physiology and Environmental Science, University of Nottingham, Sutton Bonington, United Kingdom.
authors.forename: N M
authors.initials: NM
authors.lastname: Crout
authors.forename: N A
authors.initials: NA
authors.lastname: Beresford
authors.forename: B J
authors.initials: BJ
authors.lastname: Howard
authors.forename: R W
authors.initials: RW
authors.lastname: Mayes
authors.forename: H S
authors.initials: HS
authors.lastname: Hansen
mesh_terms: D000042:Absorption; D000818:Animals; D002118:Calcium / Q000008:administration & dosage / Q000378:metabolism*; D002132:Calcium Radioisotopes / Q000378:metabolism; D004032:Diet; D005260:Female; D005506:Food Contamination; D006041:Goats / Q000378:metabolism*; D007700:Kinetics; D007774:Lactation; D008892:Milk / Q000378:metabolism*; D008954:Models, Biological; D013326:Strontium Radioisotopes / Q000493:pharmacokinetics*
chemical_list: D002132:Calcium Radioisotopes; D013326:Strontium Radioisotopes; D002118:Calcium