Infiltration of the central nervous system by a granulosa cell tumor immunostained by antibodies against inhibin.
Involvement of the CNS by a granulosa cell tumor of the ovary is rare. We describe a patient with leptomeningeal and cerebral cortex infiltration by this tumor. The diagnosis was confirmed by CSF cytology and immunocytochemistry using monoclonal antibodies against human inhibin.
Schnittger
C
C
Department of Neurology, Medizinische Hochschule Hannover, Germany.
Soudah
B
B
von Wasielewski
R
R
de Groot
M
M
Haubitz
B
B
Becker
H
H
Dengler
R
R
D000906:Antibodies; D001932:Brain Neoplasms / Q000473:pathology / Q000556:secondary*; D002540:Cerebral Cortex; D005260:Female; D006106:Granulosa Cell Tumor / Q000473:pathology / Q000556:secondary*; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D007265:Inhibins / Q000032:analysis*; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000473:pathology / Q000556:secondary*; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology*; D013120:Spinal Cord Neoplasms / Q000473:pathology / Q000556:secondary*
D000906:Antibodies; D007265:Inhibins