title: [Evaluation of the risk of decompression disease during hypobaric decompression from the standpoint of the probability theory].
abstract: Author's probabilistic theory of decompression sickness (DS) asserts that DS risk for human subjects during a single-stage reduction of pressure will be rated by distribution of estimated nucleation efficiency in the "worst" body tissues and its critical value as a function of initial nitrogen pressure, end-pressure, and bubble growth dynamics. The method was tested in the analysis of literature on the DS risk during altitude exposures with preliminary denitrogenation of varying length. Results of the analysis suggest that washing out half of nitrogen from the "worst" tissues will take minimum 480 minutes instead of 360 minutes. Calculated parameters of nucleation in tissues were used to plot DS risk due to hypobaric decompression against the final pressure. Influence of physical activity on nucleation parameters and DS risk curves is discussed.
authors.forename: V P
authors.initials: VP
authors.lastname: Nikolaev
mesh_terms: D003664:Decompression / Q000009:adverse effects* / Q000379:methods; D003665:Decompression Sickness / Q000209:etiology*; D006801:Humans; D008962:Models, Theoretical; D009584:Nitrogen; D005082:Physical Exertion; D011338:Probability Theory; D012307:Risk Factors
chemical_list: D009584:Nitrogen
vernacular_title: Otsenka riska dekompressionoĭ bolezni pri gipobaricheskikh dekompressiakh s pozitsiĭ veroiatnostnoĭ teorii.