[Pulmonary mucormycosis in a leukemia patient. Diagnostic and therapeutic difficulties].
The observation of pulmonary mucormycosis occurring in a patient presenting with aplasia induced therapeutically during treatment for acute myeloblastic leukaemia, has led to a review of the characteristics of this rare opportunistic fungal infection: it occurs in a particular condition; the clinical manifestations are characterised by the thrombotic character and the rapidly necrosing nature of the histological lesions; the diagnosis is usually very difficult to make and is linked to the rarity of the pathology and the frequently negative mycological specimens apart from tissue biopsies; the value of a medicosurgical therapeutic strategy on which the prognosis of the infection depends.
Nourdine
K
K
Service de Pneumologie et de Réanimation Respiratoire, Hôpital Tenon, Paris.
Telfour
A
A
Antoine
M
M
Roux
P
P
Zini
J M
JM
Cadranel
J
J
D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001992:Bronchoalveolar Lavage Fluid; D001999:Bronchoscopy; D006469:Hemoptysis / Q000175:diagnosis; D006801:Humans; D016867:Immunocompromised Host; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy*; D008172:Lung Diseases, Fungal / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D009336:Necrosis; D009894:Opportunistic Infections / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy; D011379:Prognosis; D011655:Pulmonary Embolism / Q000175:diagnosis / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed
D000935:Antifungal Agents; D000666:Amphotericin B
Mucormycose pulmonaire chez un patient leucémique. Difficultés diagnostique et thérapeutique.