title: The natural history of macular pseudoholes.
abstract: OBJECTIVE
  To report the natural history of macular pseudoholes with regard to ophthalmoscopic appearance and visual acuity.
  
  
  METHODS
  Thirty-six eyes of 34 patients with macular pseudoholes who were followed up for 1 year or longer were retrospectively evaluated to compare the initial ophthalmoscopic appearance and visual acuity with the most recent follow-up appearance and visual acuity.
  
  
  RESULTS
  Mean visual acuity at initial examination was 20/32 (median, 20/30); mean follow-up visual acuity was 20/32 (median, 20/30). Fourteen eyes (39%) had identical initial and final visual acuities, and 30 eyes (83%) had final visual acuity within 2 lines on the visual acuity chart from their initial examination. Four eyes had improved visual acuity of more than 2 lines, and two eyes lost more than 2 lines of visual acuity. Thirty-one eyes had adequate initial and follow-up photographs allowing comparison of macular appearance. Twenty-three (74%) of the 31 eyes showed a definitive change in macular appearance.
  
  
  CONCLUSIONS
  Visual acuity in patients with macular pseudoholes tended to remain stable. However, the macular appearance changed in 74% of eyes.
authors.affiliation: Wake Forest University Eye Center, Bowman Gray School of Medicine, Winston-Salem, North Carolina 27157-1033, USA. cgreven@bgsm.edu
authors.forename: C M
authors.initials: CM
authors.lastname: Greven
authors.forename: M M
authors.initials: MM
authors.lastname: Slusher
authors.forename: C N
authors.initials: CN
authors.lastname: Czyz
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy; D012167:Retinal Perforations / Q000209:etiology / Q000473:pathology / Q000503:physiopathology*; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology*