title: Toxoplasma encephalitis in a HIV patient: unusual involvement of the corpus callosum.
abstract: In patients with acquired immuno-deficiency syndrome, the differential diagnosis between primary brain lymphoma and toxoplasma encephalitis is not radiologically always straightforward, especially in the presence of a solitary cerebral lesion. In this context, involvement of the corpus callosum is almost exclusively associated with primary brain lymphoma. We describe here an HIV-infected patient who presented with a single and large cerebral lesion affecting the corpus callosum, suggestive of primary brain lymphoma on MRI-scan but who nonetheless responded clinically and radiologically to an anti-toxoplasma drug trial confirming the diagnosis of toxoplasma encephalitis.
authors.affiliation: Department of Neurology, Brugmann Hospital, Free University of Brussels (ULB), Belgium.
authors.forename: F
authors.initials: F
authors.lastname: Supiot
authors.forename: M P
authors.initials: MP
authors.lastname: Guillaume
authors.forename: N
authors.initials: N
authors.lastname: Hermanus
authors.forename: N
authors.initials: N
authors.lastname: Telerman-Toppet
authors.forename: R
authors.initials: R
authors.lastname: Karmali
mesh_terms: D000328:Adult; D000818:Animals; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology*; D003337:Corpus Callosum / Q000473:pathology*; D003937:Diagnosis, Differential; D004660:Encephalitis / Q000150:complications / Q000188:drug therapy / Q000209:etiology*; D006679:HIV Seropositivity / Q000150:complications*; D006801:Humans; D008223:Lymphoma / Q000150:complications / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D011739:Pyrimethamine / Q000627:therapeutic use; D013411:Sulfadiazine / Q000627:therapeutic use; D016781:Toxoplasmosis, Cerebral / Q000150:complications*
chemical_list: D000890:Anti-Infective Agents; D013411:Sulfadiazine; D011739:Pyrimethamine