title: Urinary tract infections with Aerococcus urinae in the south of The Netherlands.
abstract: Aerococcus urinae is an uncommon urinary tract pathogen that causes infections predominantly in elderly persons with local or general predisposing conditions. During a one-year study, the clinical features of Aerococcus urinae urinary tract infections (> or = 10(5) cfu/ml) were investigated in two large medical microbiology laboratories in the Netherlands. The incidence of Aerococcus urinae urinary tract infections ranged between 0.31 and 0.44% for the two laboratories. The median age (range 35-95 years) of patients with this infection was 82.5 years for women and 77.5 for men. Men had significantly (p < 0.01) more local predisposing conditions than did women. Underlying systemic diseases such as diabetes mellitus, malignancy, and dementia were found in 67.5% of patients. Most patients (97.5%) had the classic signs of a urinary tract infection, but none of them developed serious symptoms. All isolates tested were susceptible to penicillin, amoxicillin, and nitrofurantoin, 78.3% were susceptible to norfloxacin, and all were resistant to sulfonamides. The majority of patients were treated with amoxicillin, amoxicillin with clavulanic acid, or norfloxacin.
authors.affiliation: Department of Medical Microbiology, St. Elisabeth Hospital, Tilburg, The Netherlands.
authors.forename: P M
authors.initials: PM
authors.lastname: Schuur
authors.forename: M E
authors.initials: ME
authors.lastname: Kasteren
authors.forename: L
authors.initials: L
authors.lastname: Sabbe
authors.forename: M C
authors.initials: MC
authors.lastname: Vos
authors.forename: M M
authors.initials: MM
authors.lastname: Janssens
authors.forename: A G
authors.initials: AG
authors.lastname: Buiting
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004912:Erythrocytes / Q000473:pathology; D005260:Female; D005334:Fever / Q000209:etiology; D006417:Hematuria / Q000209:etiology; D006801:Humans; D006965:Hyperplasia / Q000209:etiology; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009426:Netherlands / Q000453:epidemiology; D011776:Pyuria / Q000209:etiology; D013289:Streptococcaceae / Q000302:isolation & purification*; D013290:Streptococcal Infections / Q000188:drug therapy / Q000652:urine*; D014525:Urethral Stricture / Q000209:etiology; D014549:Urinary Incontinence / Q000209:etiology; D014552:Urinary Tract Infections / Q000150:complications / Q000453:epidemiology* / Q000382:microbiology*; D014555:Urination Disorders / Q000209:etiology
chemical_list: D000900:Anti-Bacterial Agents