[Cardioprotective effect of taurine].
The review analyses data which had been accumulated in the recent years on the pharmacological properties of the inhibiting amino acid taurine concerning its cardiotropic action. The results of experimental and clinical studies of the beneficial effect of this compound on pathologically changed function of the heart are shown, and the mechanisms of this effect both on the cellular and systemic level are discussed.
Torkunov
P A
PA
Department of Neuropharmacology, Russian Academy of Medical Sciences, St. Petersburg, Russia.
Sapronov
N S
NS
D000818:Animals; D000975:Antioxidants / Q000494:pharmacology* / Q000627:therapeutic use; D001161:Arteriosclerosis / Q000378:metabolism / Q000517:prevention & control; D002317:Cardiovascular Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology; D006801:Humans; D015428:Myocardial Reperfusion Injury / Q000378:metabolism / Q000503:physiopathology / Q000517:prevention & control; D009206:Myocardium / Q000378:metabolism; D017933:Peripheral Nervous System / Q000187:drug effects; D013654:Taurine / Q000494:pharmacology* / Q000502:physiology / Q000627:therapeutic use
D000975:Antioxidants; D002317:Cardiovascular Agents; D013654:Taurine
Kardioprotektornoe deĭstvie taurina.