Mycosis fungoides with focal segmental glomerular sclerosis and nephrotic syndrome.
Cutaneous T-cell lymphoma includes mycosis fungoides and the leukemic variant, Sézary syndrome. We report the first two cases of focal segmental glomerulosclerosis in patients with cutaneous T-cell lymphoma, with nephrotic range proteinuria and review the literature on renal disease coexisting with cutaneous T-cell lymphoma. We hypothesize that glomerular injury in cutaneous T-cell lymphoma may be related to interleukin-2.
Cather
J C
JC
Division of Medical Specialties, University of Texas Medical School, Houston, USA.
Jackow
C
C
Yegge
J
J
Hagemeister
F
F
Duvic
M
M
D001706:Biopsy; D003131:Combined Modality Therapy; D005923:Glomerulosclerosis, Focal Segmental / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007668:Kidney / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009182:Mycosis Fungoides / Q000175:diagnosis* / Q000628:therapy; D009404:Nephrotic Syndrome / Q000175:diagnosis* / Q000628:therapy; D011507:Proteinuria / Q000175:diagnosis / Q000628:therapy; D012535:Scalp / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000628:therapy