title: [Adrenergic mechanisms of pain regulation].
abstract: The authors briefly account the opioidergic regulation of pain and postulate a concept of adrenergic pain-relieving systems. They also analyze the analgetic and vegetocorrecting effects of clofelin and its benefits as a centrally acting non-opiate analgetic. They discuss the status and prospects for optimization of non-opiate anesthesia in clinical practice.
authors.forename: Iu D
authors.initials: IuD
authors.lastname: Ignatov
authors.forename: A A
authors.initials: AA
authors.lastname: Zaĭtsev
mesh_terms: D018663:Adrenergic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D000320:Adrenergic Fibers / Q000187:drug effects*; D000698:Analgesia / Q000379:methods*; D000700:Analgesics / Q000008:administration & dosage / Q000627:therapeutic use; D000818:Animals; D004305:Dose-Response Relationship, Drug; D006801:Humans; D010146:Pain / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D018663:Adrenergic Agents; D000700:Analgesics
vernacular_title: Adrenergicheskie mechanizmy reguliatsii boli]