title: Effect of genetics, vaccine dosage, and postvaccination sampling interval on early antibody response to Salmonella enteritidis vaccine in broiler breeder chicks.
abstract: Broiler breeder chicks of two different genetic lines were evaluated for early antibody response to Salmonella enteritidis (SE) vaccine. Antibody responses to three dosages of SE vaccine administered at 22 d of age were measured at 3, 6, and 10 d postvaccination. Within each line, antibody levels at 10 d postvaccination were significantly higher than at either 3 or 6 d postvaccination. At all vaccine dosages, there was a significant antibody-response difference between the genetic lines at 6 and 10 d postvaccination. The vaccine dosage significantly affected antibody levels in one of the two genetic lines. These results demonstrate a genetic component of early antibody response to SE vaccine in broiler breeder chicks.
authors.affiliation: Department of Animal Science, Iowa State University, Ames, Iowa 50011-3150, USA.
authors.forename: M G
authors.initials: MG
authors.lastname: Kaiser
authors.forename: T
authors.initials: T
authors.lastname: Wing
authors.forename: S J
authors.initials: SJ
authors.lastname: Lamont
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D000907:Antibodies, Bacterial / Q000096:biosynthesis*; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000276:immunology*; D002645:Chickens / Q000235:genetics / Q000276:immunology*; D015331:Cohort Studies; D004306:Dose-Response Relationship, Immunologic; D008297:Male; D012477:Salmonella enteritidis / Q000276:immunology*; D013997:Time Factors; D014611:Vaccination / Q000662:veterinary*
chemical_list: D000907:Antibodies, Bacterial; D001428:Bacterial Vaccines