title: [Comparative analysis of the VP2 variable region of the gene from infectious bursal disease virus isolates].
abstract: Variable cDNA regions in the VP2 gene of 24 isolates of infectious bursal disease virus (IBDV) isolated in Russia in 1993-1996 were amplified by the "nested" PCR and sequenced. The primary structure analysis of the VP2 gene variable region revealed 2 major groups of IBDV isolates. The first group consisted of the isolates with the structure identical or closely related to the highly virulent European strains CS89, 74/89A, 661, JY86, and DV86, the second group included the isolates with a high level of homology to the vaccine strains PBG98 and Cu-1. In addition, two isolates with original structure were identified, which differed from previously studied strains.
authors.forename: L O
authors.initials: LO
authors.lastname: Shcherbakova
authors.forename: A I
authors.initials: AI
authors.lastname: Lomakin
authors.forename: A V
authors.initials: AV
authors.lastname: Borisov
authors.forename: V V
authors.initials: VV
authors.lastname: Drygin
authors.forename: A A
authors.initials: AA
authors.lastname: Gusev
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D004279:DNA, Viral; D007243:Infectious bursal disease virus / Q000235:genetics* / Q000276:immunology; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid; D015678:Viral Structural Proteins / Q000235:genetics*; D014765:Viral Vaccines / Q000235:genetics
chemical_list: D004279:DNA, Viral; C082513:VP2 protein, infectious bursal disease virus; D015678:Viral Structural Proteins; D014765:Viral Vaccines
vernacular_title: Sravnitel'nyĭ analiz variabel'noĭ oblasti gena VP2 izoliatov virusa infektsionnoĭ bursal'noĭ bolezni.