[Splanchnic portal circulation (enhancement of radiologic image intensity and of visibility of collateral branches with prostaglandin E1)].
The authors present the results of a comparative study of mesenterico-portographies with and without the use of Prostaglandin E1 (PGE1) injected intrarterially into the superior mesenteric artery as an adjunct to the radiographic procedure. Twenty eight patients, with varied hepatic and biliopancreatic ailments, referred to the Radiologic Department for angiographic appraisal of the splanchnic circulation were studied. Two series of radiographies were realized after catheterization of the superior mesenteric artery: a first after the injection of the contrast only and a second after the injection of 50 micrograms of PGE1 as a bolus prior the contrast means. The difference in opacification of the various segments of the portal system and the lapse of time necessary to attain the maximum radiographic density were appraised. They observed that, with the use of PGE1 was attained a regular, intense and swift opacification of the superior mesenteric vein, portal vein and intrahepatic branches in all patients that had those segments previous and/or hepatotropic circulation. There was a significative reduction in the lapse of time necessary to attain the maximum opacification. Also they observed, with the use of the PGE1, the opacification of collateral branches of the portal system in more patients and intensification in those that were previously opacified. Because of the good results attained with the use of the PGE1, its transitory pharmacologic action and absence of collateral reactions with the dose used, they recommend its regular use when this investigation is performed.
Widman
A
A
Departamento de Radiologia-INRAD-do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo-FMUSP.
Speranzini
M B
MB
Saad
W A
WA
D000527:Alprostadil / Q000494:pharmacology*; D005260:Female; D005706:Gallbladder Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging; D006801:Humans; D008103:Liver Cirrhosis / Q000000981:diagnostic imaging; D008297:Male; D017538:Mesenteric Artery, Superior; D011168:Portal System / Q000000981:diagnostic imaging* / Q000187:drug effects*; D011172:Portography; D011856:Radiographic Image Enhancement / Q000379:methods*; D012552:Schistosomiasis / Q000000981:diagnostic imaging; D013152:Splanchnic Circulation / Q000187:drug effects*; D014665:Vasodilator Agents / Q000494:pharmacology*
D014665:Vasodilator Agents; D000527:Alprostadil
Circulação portal esplâncnica. (Reforço da intensidade da imagem radiológica e aumento da visibilização de colaterais com emprego da prostaglandina E1).