Successful treatment of acute promyelocytic leukemia using all-trans retinoic acid and erythropoietin in a Jehovah's Witness boy.
A 10-year-old boy with acute promyelocytic leukemia (APL) was treated with all-trans-retinoic acid (ATRA) at a dose of 60 mg/m2/day. Recombinant erythropoietin was also used. The patient parents and other relatives, all Jehova's Witnesses, refused any type of hemotherapy. After 43 days of ATRA treatment complete remission was obtained without the use of hemotherapy. This case exemplifies the advantages provided by ATRA treatment in APL.
Menéndez
A
A
Institute of Hematology, Ciudad de la Habana, Cuba.
Svarch
E
E
Martínez
G
G
Hernández
P
P
D002648:Child; D002835:Christianity; D004921:Erythropoietin / Q000627:therapeutic use*; D006801:Humans; D015473:Leukemia, Promyelocytic, Acute / Q000188:drug therapy*; D008297:Male; D011994:Recombinant Proteins; D014212:Tretinoin / Q000627:therapeutic use*
D011994:Recombinant Proteins; D004921:Erythropoietin; D014212:Tretinoin