title: Transcatheter uterine artery embolisation to treat large uterine fibroids.
abstract: Bilateral uterine artery embolisation was performed to treat eight women with symptomatic large fibroids requiring treatment. Uterine volume was quantitatively assessed by magnetic resonance imaging. Both uterine arteries were occluded effectively in all women, and the procedure was well tolerated, with a 24-36 hour admission for pain relief. The level of pain experienced was variable, but well controlled. Some women experienced intermittent vaginal discharge and pain following the procedure. Improvement of symptoms occurred in six of the seven women and the eighth woman conceived. There were no significant complications. At three months four women had a uterine volume of < 350 cm3. Embolisation appears to be a good alternative to surgery, but longer follow up is required to evaluate the long term effects and to determine those patients for whom the procedure is suitable.
authors.affiliation: Department of Obstetrics and Gynaecology, UMDS and Guy's Hospital Trust, London.
authors.forename: E A
authors.initials: EA
authors.lastname: Bradley
authors.forename: J F
authors.initials: JF
authors.lastname: Reidy
authors.forename: R G
authors.initials: RG
authors.lastname: Forman
authors.forename: J
authors.initials: J
authors.lastname: Jarosz
authors.forename: P R
authors.initials: PR
authors.lastname: Braude
mesh_terms: D000328:Adult; D000700:Analgesics / Q000627:therapeutic use; D002404:Catheterization; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007889:Leiomyoma / Q000150:complications / Q000628:therapy*; D008875:Middle Aged; D010146:Pain / Q000517:prevention & control; D014594:Uterine Neoplasms / Q000150:complications / Q000628:therapy*; D014599:Uterus / Q000098:blood supply
chemical_list: D000700:Analgesics