title: [The role of conformational mobility in the decay of free-radical states in proteins].
abstract: The kinetic study of decay reaction of macroradicals in proteins with the use of a stochastic dynamic model of proteins has been carried out. Two types of distributions of the effective coefficients (diffusion, friction and viscosity) corresponding to two types of conformational motion of proteins have been obtained. The distributions of the effective parameters corresponding to the diffusion of protein molecule over conformational states are equal for all. The distributions of the same parameters corresponding to the diffusion of individual atomic groups in protein molecule are different and influenced by proteins, temperature and humidity. In dry proteins macroradicals disappear at the more conformational mobility only as compared with proteins in water.
authors.affiliation: Akmolinsk State Medical Institute, Ministry of Health, Kazakhstan.
authors.forename: A A
authors.initials: AA
authors.lastname: Iskakov
authors.forename: K M
authors.initials: KM
authors.lastname: L'vov
mesh_terms: D005609:Free Radicals; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*
chemical_list: D005609:Free Radicals; D011506:Proteins
vernacular_title: Rol' konformatsionnoĭ podvizhnosti v gibeli svobodnoradikal'nykh sostoianiĭ v belkakh.