Flutamide photosensitivity--residual vitiliginous lesions.
A case of flutamide photosensitivity is reported in a patient receiving treatment for prostate cancer. Photopatch testing with flutamide at 10 and 20% in acetone was positive and controls negative. Other reports in the literature indicate that flutamide photosensitivity can be produced either by UV-A or UV-B, but the small number of reports and the differences in the tests performed do not allow the specific characteristics of flutamide photosensitivity to be established. Presently it would be advisable, due to the frequent use of this drug, to include flutamide in the investigation of photosensitive patients.
Vilaplana
J
J
Servei de Dermatologia, Hospital Clínic i Provincial, Facultat de Medicina, Universitat de Barcelona, Spain.
Romaguera
C
C
Azón
A
A
Lecha
M
M
D000368:Aged; D000726:Androgen Antagonists / Q000009:adverse effects* / Q000627:therapeutic use; D017454:Dermatitis, Photoallergic / Q000209:etiology*; D003875:Drug Eruptions / Q000209:etiology; D005485:Flutamide / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000188:drug therapy; D012867:Skin / Q000187:drug effects / Q000473:pathology / Q000528:radiation effects; D014820:Vitiligo / Q000139:chemically induced*
D000726:Androgen Antagonists; D005485:Flutamide