title: Localized scleroderma.
abstract: Localized scleroderma can be divided into three main subtypes: morphea, linear scleroderma, and generalized morphea. Plaque morphea usually has a good prognosis. Variants of morphea, including guttate morphea and atrophoderma of Pasini and Pierini, are seen. Linear scleroderma, whether involving an extremity or the face, is often associated with serological abnormalities. Cosmetic and functional prognosis may be poor. Therapy is usually ineffective. Generalized morphea may be difficult to differentiate from systemic scleroderma. However, progression to systemic scleroderma is uncommon.
authors.affiliation: University of California, San Francisco 94108, USA.
authors.forename: D L
authors.initials: DL
authors.lastname: Tuffanelli
mesh_terms: D000328:Adult; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012594:Scleroderma, Localized / Q000453:epidemiology / Q000473:pathology* / Q000503:physiopathology*