Comparison between two prospective studies of cardiovascular disease carried out amongst renal replacement patients in UK and Italy.
The data on 256 non-diabetic patients entering renal replacement therapy (RRT) in Manchester between 1 January 1983 and 31 December 1986 were compared with those on 84 non-diabetic patients entering RRT in Milan between 1 January 1983 and 31 December 1988. In each unit, patients had been studied prospectively and the findings were entered on the same database for this report. At the end of the study, 68% of patients were alive in each centre and in each 16% had died from cardiovascular disease. 11% of Manchester and 18% of the Milan patients developed angina. The data do not support the view that there is a differential risk for cardiovascular disease in the Northern and Southern parts of Europe and it may be advisable to study the matter prospectively in a larger patient cohort.
Brown
J H
JH
Department of Renal Medicine, Royal Infirmary, Manchester, UK.
Fellin
G
G
Hunt
L P
LP
Vites
N P
NP
D'Amico
G
G
Mallick
N P
NP
D000293:Adolescent; D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000209:etiology; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000401:mortality; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000009:adverse effects; D016016:Proportional Hazards Models; D011446:Prospective Studies; D006435:Renal Dialysis / Q000009:adverse effects; D017582:Renal Replacement Therapy / Q000009:adverse effects*; D016019:Survival Analysis