[The proliferative activity of the erythroblasts in the erythroblastic islands of rat bone marrow].
Administration of erythropoietin augmented the mitotic activity in the erythroid crown of erythroblastic islands in polycythemic as well as normal rats. The phenomenon seems to be due to activation of erythropoietic synthesis by the central macrophage in reconstructing erythroblastic islands.
Zakharov
Iu M
IuM
Medical Academy, Cheliabinsk, Russia.
Medianik
B V
BV
D000208:Acute Disease; D000740:Anemia / Q000097:blood / Q000209:etiology; D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology* / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D004900:Erythroblasts / Q000166:cytology* / Q000187:drug effects; D004920:Erythropoiesis / Q000187:drug effects; D004921:Erythropoietin / Q000494:pharmacology; D005260:Female; D006470:Hemorrhage / Q000097:blood / Q000150:complications; D008938:Mitosis / Q000187:drug effects; D011086:Polycythemia / Q000097:blood; D051381:Rats; D013997:Time Factors
D004921:Erythropoietin
O proliferativnoĭ aktivnosti éritroblastov v éritroblasticheskikh ostrovkakh kostnogo mozga u krys.