Medicinal and other products and human and animal transmissible spongiform encephalopathies: memorandum from a WHO meeting.
The report in March 1996 of 10 human cases of a novel from of Creutzfeldt-Jakob disease in the United Kingdom, and its possible link to the agent that causes bovine spongiform encephalopathy (BSE), raises many questions about the safety of animal-derived products and by-products entering the food chain or being used in medicine. This Memorandum updates the preventive measures put forward in 1991 to minimize the risks associated with the use of bovine-derived materials in medicinal products and medical devices.
D000328:Adult; D000818:Animals; D001672:Biocompatible Materials / Q000009:adverse effects*; D001798:Blood Proteins / Q000009:adverse effects; D002417:Cattle; D007562:Creutzfeldt-Jakob Syndrome / Q000382:microbiology / Q000517:prevention & control / Q000635:transmission*; D016643:Encephalopathy, Bovine Spongiform / Q000635:transmission*; D005516:Food Microbiology; D006801:Humans; D008892:Milk / Q000009:adverse effects; D018621:PrPC Proteins / Q000472:pathogenicity; D012756:Sheep; D015047:Zoonoses
D001672:Biocompatible Materials; D001798:Blood Proteins; D018621:PrPC Proteins