title: Exploring novel chemotherapy treatments using the WWW.
abstract: A JAVA application, The Oncologists Workbench, which allows oncologists to estimate the influence of new cancer treatment schedules is being developed. The requirement for a rational approach to the design of chemotherapeutic regimens is well established [1]. Our prototype allows oncologists using the World Wide Web (WWW) to graphically construct treatment regimens while considering various toxic side effects. A simulation engine makes predictions of tumour growth based on previous clinical knowledge of response to treatment. The oncologist can then examine the predicted tumour response information with a specially constructed interactive viewer. These interlinked tools allow oncologists to develop and predict the effectiveness of novel chemotherapeutic regimens. This work is part of an ongoing collaboration between oncologists, mathematicians and computer scientists to provide tools for improving cancer chemotherapy.
authors.affiliation: School of Computer and Mathematical Sciences, The Robert Gordon University, Aberdeen, Scotland, UK. jb@scms.rgu.ac.uk
authors.forename: J
authors.initials: J
authors.lastname: Boyle
authors.forename: D
authors.initials: D
authors.lastname: Henderson
authors.forename: J
authors.initials: J
authors.lastname: McCall
authors.forename: H
authors.initials: H
authors.lastname: McLeod
authors.forename: J
authors.initials: J
authors.lastname: Usher
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002985:Clinical Protocols; D003195:Computer Communication Networks; D003196:Computer Graphics; D003198:Computer Simulation; D003199:Computer Systems; D005544:Forecasting; D006801:Humans; D008954:Models, Biological; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology; D012984:Software; D014584:User-Computer Interface
chemical_list: D000970:Antineoplastic Agents