title: [Multicentric Castleman's disease with mediastinal involvement in a patient with HIV infection].
abstract: Castleman's disease is most often seen by a thoracic physician as a mediastinal tumour which is discovered fortuitously and whose surgical excision leads to a cure. We report a case of a patient of 30 who was seropositive for HIV and was suffering from Castleman's disease initially localised to the mediastinum. The disease was associated with a cutaneous and bronchial Kaposi sarcoma. The mediastinal disease, associated with cutaneous and bronchial Kaposi sarcoma, was marked by evolving in a multicentric manner. We review the histological definition and recent data concerning the pathophysiology and the diagnostic and therapeutic management of this disorder and the very varied clinical expression.
authors.affiliation: Service de Pneumologie et Réanimation Respiratoire, Hôpital Tenon, Paris.
authors.forename: E
authors.initials: E
authors.lastname: Azoulay
authors.forename: I
authors.initials: I
authors.lastname: Herry
authors.forename: M
authors.initials: M
authors.lastname: Antoine
authors.forename: C
authors.initials: C
authors.lastname: Mayaud
authors.forename: J
authors.initials: J
authors.lastname: Cadranel
mesh_terms: D000328:Adult; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D001984:Bronchial Neoplasms / Q000150:complications; D005871:Castleman Disease / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D015658:HIV Infections / Q000150:complications*; D006679:HIV Seropositivity; D006801:Humans; D008297:Male; D008477:Mediastinal Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D012514:Sarcoma, Kaposi / Q000150:complications; D012878:Skin Neoplasms / Q000150:complications; D014747:Vinblastine / Q000627:therapeutic use
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D014747:Vinblastine
vernacular_title: Maladie de Castleman multicentrique à expression médiastinale chez un patient infecté par le VIH.