title: Imaging of the brain using the fast-spin-echo and gradient-spin-echo techniques.
abstract: The aim of our study was to compare gradient-spin-echo (GRASE) to fast-spin-echo (FSE) sequences for fast T2-weighted MR imaging of the brain. Thirty-one patients with high-signal-intensity lesions on T2-weighted images were examined on a 1.5-T MR system. The FSE and GRASE sequences with identical sequence parameters were obtained and compared side by side. Image assessment criteria included lesion conspicuity, contrast between different types of normal tissue, and image artifacts. In addition, signal-to-noise, contrast-to-noise, and contrast ratios and were determined. The FSE technique demonstrated more lesions than GRASE and with generally better conspicuity. Smaller lesions in particular were better demonstrated on FSE because of lower image noise and slightly weaker image artifacts. Gray-white differentiation was better on FSE. Ferritin and hemosiderin depositions appeared darker on GRASE, which resulted in better contrast. Fatty tissue was less bright on GRASE. With current standard hardware equipment, the FSE technique seems preferable to GRASE for fast T2-weighted routine MR imaging of the brain. For the assessment of hemosiderin or ferritin depositions, GRASE might be considered.
authors.affiliation: Department of Radiology, University of Vienna, AKH, Währinger Gürtel 18-20, A-1090 Vienna, Austria.
authors.forename: W
authors.initials: W
authors.lastname: Umek
authors.forename: A
authors.initials: A
authors.lastname: Ba-Ssalamah
authors.forename: R
authors.initials: R
authors.lastname: Prokesch
authors.forename: R
authors.initials: R
authors.lastname: Mallek
authors.forename: K
authors.initials: K
authors.lastname: Heimberger
authors.forename: K
authors.initials: K
authors.lastname: Hittmair
mesh_terms: D000273:Adipose Tissue / Q000473:pathology; D000293:Adolescent; D000328:Adult; D000368:Aged; D016477:Artifacts; D001479:Basal Ganglia / Q000473:pathology; D001921:Brain / Q000473:pathology*; D001927:Brain Diseases / Q000473:pathology*; D001933:Brain Stem / Q000473:pathology; D002531:Cerebellum / Q000473:pathology; D002552:Cerebral Ventricles / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D003199:Computer Systems; D005260:Female; D005293:Ferritins / Q000032:analysis; D005917:Globus Pallidus / Q000473:pathology; D006485:Hemosiderin / Q000032:analysis; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D013788:Thalamus / Q000473:pathology
chemical_list: D005293:Ferritins; D006485:Hemosiderin