title: [Effect of oxygen inhalation on hemodynamics in chronic thromboembolic pulmonary hypertension].
abstract: OBJECTIVE
  This study evaluates the haemodynamic effects of oxygen inhalation on pulmonary artery pressure and pulmonary vascular resistance in patients with chronic thromboembolic pulmonary hypertension.
  
  
  METHODS
  In 47 patients with chronic thromboembolic pulmonary hypertension haemodynamic parameters were measured before and after oxygen inhalation.
  
  
  RESULTS
  In moderately severe and severe pulmonary hypertension oxygen inhalation significantly reduced mean pulmonary artery pressure by about 11.1% and 4.6%, respectively. However, pulmonary vascular resistance was not significantly affected. Oxygen saturation improved and heart rate was reduced. Cardiac index decreased in severe pulmonary hypertension. Systemic vascular resistance increased.
  
  
  CONCLUSIONS
  We conclude that oxygen inhalation reduces pulmonary artery pressure and improves oxygen supply in patients with moderately severe and severe chronic thromboembolic pulmonary hypertension.
authors.affiliation: Klinik für Radiologie, Johannes Gutenberg-Universität Mainz.
authors.forename: M B
authors.initials: MB
authors.lastname: Pitton
authors.forename: C
authors.initials: C
authors.lastname: Düber
authors.forename: E
authors.initials: E
authors.lastname: Mayer
authors.forename: M
authors.initials: M
authors.lastname: Thelen
mesh_terms: D001794:Blood Pressure; D002245:Carbon Dioxide / Q000097:blood; D002302:Cardiac Output; D002908:Chronic Disease; D005260:Female; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D006976:Hypertension, Pulmonary / Q000503:physiopathology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D010102:Oxygen Inhalation Therapy; D010313:Partial Pressure; D011651:Pulmonary Artery; D011652:Pulmonary Circulation; D011655:Pulmonary Embolism / Q000503:physiopathology* / Q000628:therapy*; D014655:Vascular Resistance
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen
vernacular_title: Auswirkungen der Sauerstoffinhalation auf die Hämodynamik bei chronischer thromboembolischer pulmonaler Hypertonie.