[Effectiveness of cefpirome on Klebsiella pneumoniae producing beta-lactamases with an extended spectrum of activity].
In the submitted paper the author investigated the effectiveness of cefpirome on Klebsiella pneumoniae strains producing beta-lactamases with an extended spectrum (ESBL). From a total of 1348 examined strains of Klebsiella pneumoniae ESBL production was confirmed in 59 strains (4.4%). Resistance of ESBL-positive strains of Klebsiella pneumoniae to ceftazidime was 83.1%, to cefotaxime 93.2%, while resistance to cefpirome was recorded only in 45.8%.
Kolár
M
M
Mikrobiologický ústav, Lékarská fakulta Univerzity Palackého, Olomouc.
D002511:Cephalosporins / Q000494:pharmacology*; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000201:enzymology; D008826:Microbial Sensitivity Tests; D001618:beta-Lactamases / Q000096:biosynthesis*; D000097572:Cefpirome
D002511:Cephalosporins; D001618:beta-Lactamases; D000097572:Cefpirome
Ucinnost cefpiromu na kmeny Klebsiella pneumoniae produkující beta-laktamázy s rozsíreným spektrem aktivity (ESBL).