title: Synthesis of 5H-dipyrido[1,2-a:2',3'-d]pyrimidin-5-ones as potential antiallergy agents.
abstract: A novel synthesis of 5H-dipyrido[1,2-a:2',3'-d]pyrimidin-5-ones is described. The method is based on Ullmann condensation of 2-chloronicotinic acid and its 5-bromo analoguewith 2-aminopyridine 1-oxides, followed by intramolecular cyclization of the resulting 3-carboxy-2,2'-bipyridylamine 1'-oxides with phosphorous.
authors.affiliation: Institute of Chemistry, Agricultural and Pedagogical University, Siedlce, Poland.
authors.forename: A
authors.initials: A
authors.lastname: Rykowski
authors.forename: W
authors.initials: W
authors.lastname: Pucko
mesh_terms: D018926:Anti-Allergic Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D011725:Pyridines / Q000138:chemical synthesis* / Q000494:pharmacology; D011744:Pyrimidinones / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D018926:Anti-Allergic Agents; D011725:Pyridines; D011744:Pyrimidinones