title: Assessment of a new ventricular contractile index obtained with transoesophageal echocardiography before and after cardiopulmonary bypass in cardiac surgical patients.
abstract: We have compared a new contractile index "left ventricular end-systolic wall stress-heart rate-corrected velocity of circumferential fibre shortening (vcfc)" with conventional contractile indices in 13 patients undergoing coronary artery bypass grafting. We generated the slopes of the "end-systolic wall stress-vcfc", "end-systolic wall stress-area" and "peak arterial pressure-area" relationships by altering arterial pressure before and after cardiopulmonary bypass (CPB). In all patients, significant correlations were obtained for end-systolic wall stress-area and peak arterial pressure-area relationships before and after CPB. In all patients, significant inverse linear correlations were obtained for the end-systolic wall stress-vcfc relationship before CPB; however, inverse linear correlation was absent in eight patients after CPB. It may be that the increased afterload had less influence on left ventricular systolic function after CPB as a possible mechanism of loss of the inverse linear correlation in the end-systolic wall stress-vcfc relationship.
authors.affiliation: Department of Anaesthesiology and Intensive Care, Hamamatsu University School of Medicine, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kikura
authors.forename: T
authors.initials: T
authors.lastname: Ikeda
authors.forename: T
authors.initials: T
authors.lastname: Ohnuma
authors.forename: K
authors.initials: K
authors.lastname: Ikeda
mesh_terms: D000368:Aged; D001794:Blood Pressure; D002315:Cardiopulmonary Bypass; D001026:Coronary Artery Bypass; D017548:Echocardiography, Transesophageal; D005260:Female; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D011184:Postoperative Period; D016277:Ventricular Function, Left