A comparison of the concentrations of certain pesticides and polychlorinated hydrocarbons in bone marrow and fat tissue.
Chlorinated hydrocarbon (CHC) and polychlorinated biphenyl (PCB) concentrations in the bone marrow of 29 adults were determined, referred to lipid content, and compared with literature values for adipose tissue of 20 adults in the Federal Republic of Germany. The concentrations of five of the seven investigated substances were lower in bone marrow than in fat tissue. The concentration of hexachloro-benzene (HCB) was eight-fold, the PCBsum was six-fold, the concentration of p,p'-dichlorodiphenyl-trichloroethane (p,p'-DDT) was three-fold lower in bone marrow and the concentration of p,p'-dichlorodiphenyl-dichloroethylene (p,p'-DDE) was 77% of the concentration in fat tissue. Whereas the concentration of beta-hexachlorocyclo-hexane (beta-HCH) was 41% of adipose tissue, alpha-hexachlorocyclohexane (alpha-HCH) and dieldrin, on the other hand, were increased 10- and 19-fold, respectively.
Scheele
J S
JS
UCSD School of Medicine, Department of Pathology, La Jolla, CA 92093-0612, USA.
D000273:Adipose Tissue / Q000737:chemistry*; D000328:Adult; D001853:Bone Marrow / Q000737:chemistry*; D006801:Humans; D006843:Hydrocarbons, Chlorinated / Q000032:analysis*; D011078:Polychlorinated Biphenyls / Q000032:analysis*
D006843:Hydrocarbons, Chlorinated; D011078:Polychlorinated Biphenyls