title: The glycoprotein P0 in peripheral gliogenesis.
abstract: Recent data show that during development protein zero, P0, the most abundant peripheral nerve myelin protein, is detecable long before myelination. In particular, the expression of P0 in a fraction of migrating neural crest reveals progenitor cell heterogeneity in the developing PNS. Here we review the regulation and potential function of P0 during peripheral gliogenesis.
authors.affiliation: Institute of Cell Biology, Swiss Federal Institute of Technology, ETH-Hönggerberg, CH-8093 Zürich, Switzerland.
authors.forename: L
authors.initials: L
authors.lastname: Sommer
authors.forename: U
authors.initials: U
authors.lastname: Suter
mesh_terms: D000818:Animals; D002454:Cell Differentiation / Q000187:drug effects; D006801:Humans; D018993:Myelin P0 Protein / Q000235:genetics / Q000502:physiology*; D017933:Peripheral Nervous System / Q000166:cytology / Q000254:growth & development* / Q000502:physiology*; D012583:Schwann Cells / Q000166:cytology / Q000378:metabolism* / Q000502:physiology*
chemical_list: D018993:Myelin P0 Protein