title: Pleural effusion during bromocriptine exposure in two patients with pre-existing asbestos pleural plaques: a relationship?
abstract: Two patients with pleural plaques developed pleural effusion and subsequent diffuse pleural fibrosis 50 and 39 yrs after their first exposure to asbestos. The diagnosis of benign asbestos pleural effusion was suggested, but the work-up finally suggested bromocriptine-induced pleural disease in both patients. These two cases illustrate that drug-induced pleural effusion is an important differential diagnosis of benign asbestos pleural effusion. It is, moreover, possible that pre-existing asbestos pleural lesions, or even asbestos exposure, increases the risk of developing bromocriptine-induced pleural disease.
authors.affiliation: Dept of Chest Medicine, Erasme Hospital, Brussels, Belgium.
authors.forename: C
authors.initials: C
authors.lastname: Knoop
authors.forename: M
authors.initials: M
authors.lastname: Mairesse
authors.forename: C
authors.initials: C
authors.lastname: Lenclud
authors.forename: P A
authors.initials: PA
authors.lastname: Gevenois
authors.forename: P
authors.initials: P
authors.lastname: De Vuyst
mesh_terms: D000978:Antiparkinson Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001195:Asbestosis / Q000150:complications* / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000503:physiopathology; D001971:Bromocriptine / Q000009:adverse effects* / Q000627:therapeutic use; D001992:Bronchoalveolar Lavage Fluid / Q000737:chemistry; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D010995:Pleural Diseases / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D010996:Pleural Effusion / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D011658:Pulmonary Fibrosis / Q000175:diagnosis* / Q000209:etiology; D014057:Tomography, X-Ray Computed
chemical_list: D000978:Antiparkinson Agents; D001971:Bromocriptine