Isolated intracranial involvement in Rosai-Dorfman disease: a report of two cases and review of the literature.
Rosai-Dorfman disease is an idiopathic histiocytic disorder of lymph nodes and extranodal sites. Central nervous system manifestations of this disease are rare, and to our knowledge only 16 cases of intracranial involvement have been reported previously. Intracranial Rosai-Dorfman disease clinically and radiologically resembles meningioma, and histologic examination is essential for a definitive diagnosis. We report two cases of isolated, intracranial, dural-based Rosai-Dorfman disease, review the literature, and discuss the differential diagnoses of this lesion.
Deodhare
S S
SS
Department of Pathology, St Michael's Hospital, University of Toronto, Ontario, Canada.
Ang
L C
LC
Bilbao
J M
JM
D000328:Adult; D003937:Diagnosis, Differential; D004388:Dura Mater / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure; D006644:Histiocytes / Q000473:pathology; D015618:Histiocytosis, Sinus / Q000000981:diagnostic imaging / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008579:Meningioma / Q000175:diagnosis; D008854:Microscopy, Electron; D009418:S100 Proteins / Q000032:analysis; D014057:Tomography, X-Ray Computed
D009418:S100 Proteins