title: [Usefulness of a new technique to assess drug perfusion pattern on balloon occluded arterial infusion therapy (BOAI) for intrapelvic malignant neoplasms: subtraction CT with low-flow-rate arterial injection (S-CTLA)].
abstract: The hemodynamics in balloon occluded arterial infusion therapy (BOAI) for intrapelvic malignant neoplasms is not totally understood. A new technique to evaluate the perfusion pattern of anticancer drugs under BOAI, which is named Subtraction CT with Low-flow-rate Arterial injection (S-CTLA), has been developed by us. In this technique, spiral CT data were acquired twice, before and after low-flow-rate (0.2 ml/sec) injection of contrast agent. Then, subtraction images were reconstructed. S-CTLA was performed in 3 patients with urinary bladder cancer. Our results provided demonstrable images as well as useful information in predicting the effectiveness of BOAI.
authors.affiliation: Department of Radiology, Hitachi General Hospital.
authors.forename: K
authors.initials: K
authors.lastname: Mori
authors.forename: H
authors.initials: H
authors.lastname: Yoshioka
authors.forename: K
authors.initials: K
authors.lastname: Nakajima
authors.forename: K
authors.initials: K
authors.lastname: Nozawa
authors.forename: S
authors.initials: S
authors.lastname: Sugawara
authors.forename: Y
authors.initials: Y
authors.lastname: Itai
mesh_terms: D000368:Aged; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000493:pharmacokinetics; D002295:Carcinoma, Transitional Cell / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000378:metabolism; D002404:Catheterization; D003287:Contrast Media / Q000008:administration & dosage* / Q000493:pharmacokinetics; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000379:methods*; D008297:Male; D008875:Middle Aged; D013382:Subtraction Technique; D014057:Tomography, X-Ray Computed; D001749:Urinary Bladder Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents; D003287:Contrast Media