title: [Calcitonin and otosclerosis: a preliminary clinical note].
abstract: Otosclerosis is a disorder characterized by alternating periods of bone resorption and formation as a result of a disturbance in the enzymatic balance of the otic capsule and stapedial footplate. In some cases, calcitonin administration improved the metabolic abnormalities associated with the disease. This hormone inhibits bone resorption produced by osteoclasts and facilitates osteoblastic accretion. The authors describe the results obtained in a patient with aggressive otosclerosis who experienced an improvement in hearing and tinnitus after treatment with salmon calcitonin.
authors.affiliation: Servicio de ORL, Hospital San Millán, Logroño.
authors.forename: J L
authors.initials: JL
authors.lastname: Lacosta
authors.forename: J C
authors.initials: JC
authors.lastname: Infante
authors.forename: L
authors.initials: L
authors.lastname: Sánchez Galán
mesh_terms: D000281:Administration, Intranasal; D000293:Adolescent; D001301:Audiometry, Pure-Tone; D002116:Calcitonin / Q000627:therapeutic use*; D016861:Cyclooxygenase Inhibitors / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D005260:Female; D006312:Hearing Loss, Bilateral / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D010040:Otosclerosis / Q000150:complications / Q000188:drug therapy*
chemical_list: D016861:Cyclooxygenase Inhibitors; D002116:Calcitonin
vernacular_title: Calcitonina y otosclerosis: nota clínica preliminar.