title: In vivo evaluation of a retrievable vena cava filter--the Dibie-Musset filter: experimental results.
abstract: OBJECTIVE
  To evaluate, in an animal model, the efficacy and safety of a 7 Fr percutaneous vena cava filter for temporary or permanent use.
  
  
  METHODS
  The Dibie-Musset (DM) filter is a wire preformed into a double-spiral shape with a spring effect. The experiment was performed in 15 adult sheep and consisted of the insertion of 45 filters, clot trapping tests, and filter retrieval. Follow-up in all sheep consisted of radiologic (abdominal radiograph, inferior vena cavogram, abdominal computed tomography), macroscopic, and microscopic examinations between days 8 and 386 after filter placement.
  
  
  RESULTS
  Of the 45 filters implanted in 15 sheep, 29 were retrieved between day 0 and day 15. Filtration efficiency was 100% for clots 4 x 4 x 20 mm. No long-term (1 year) side-effects were detectable. Microscopic examination of the vein wall showed only a dense intimal fibrosis without signs of acute inflammation at 1 year.
  
  
  CONCLUSIONS
  These results support the efficiency and safety of the DM filter in an animal model.
authors.affiliation: Departement Cardio-Vasculaire, Institut Mutualiste Montsouris, Choisy 6, Place de Port au Prince, F-75013 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Dibie
authors.forename: D
authors.initials: D
authors.lastname: Musset
authors.forename: M
authors.initials: M
authors.lastname: Heissler
authors.forename: J C
authors.initials: JC
authors.lastname: Fournet
authors.forename: R
authors.initials: R
authors.lastname: Palau
authors.forename: F
authors.initials: F
authors.lastname: Laborde
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D005374:Filtration; D012756:Sheep; D016306:Vena Cava Filters
chemical_list: D001672:Biocompatible Materials