title: Increased serum CA19-9 in patients with xanthogranulomatous cholecystitis.
abstract: We present three cases of xanthogranulomatous cholecystitis (XGC) with an increased serum carbohydrate antigen 19-9 (CA19-9). All of the patients were elderly females and had gallstones lodged in the neck of the gallbladder. Preoperative serum CA19-9 levels were 709 U/ml, 87 U/ml, and 400 U/ml, respectively. A cholecystectomy with or without bile duct exploration was performed, and the histological diagnosis of XGC was made. Serum CA19-9 levels fell to normal levels in two patients who recovered uneventfully, but rose again in one patient who died of cholangitis. Clinicians must remember that XGC is a possible cause of increased serum CA19-9 levels.
authors.affiliation: Department of Surgery, Saiseikai Yahata General Hospital, Kitakyushu, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Adachi
authors.forename: Y
authors.initials: Y
authors.lastname: Iso
authors.forename: M
authors.initials: M
authors.lastname: Moriyama
authors.forename: T
authors.initials: T
authors.lastname: Kasai
authors.forename: H
authors.initials: H
authors.lastname: Hashimoto
mesh_terms: D000368:Aged; D018395:CA-19-9 Antigen / Q000097:blood*; D002763:Cholecystectomy; D002764:Cholecystitis / Q000150:complications / Q000000981:diagnostic imaging / Q000276:immunology*; D002769:Cholelithiasis / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery; D005260:Female; D006099:Granuloma / Q000150:complications / Q000000981:diagnostic imaging / Q000276:immunology*; D006801:Humans; D014057:Tomography, X-Ray Computed; D014973:Xanthomatosis / Q000150:complications / Q000000981:diagnostic imaging / Q000276:immunology*
chemical_list: D018395:CA-19-9 Antigen