[The formation of electrical excitability in cultured frog embryonic myocytes].
Quantitative changes of sodium and potassium ionic currents were studied in the frog embryonic skeletal myocytes cultures under conditions preventing cell fusion and division. During 7 days of culturing the mean values of the sodium and potassium currents densities were 7- and 1.8-fold increased, resp. In currents clamp records the APs were observed only after 5 days of culturing, and in cells with proportion of sodium and potassium conductances above the critical level.
Katina
I E
IE
Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Acad. Sci., St. Petersburg, Russia.
Luk'ianenko
V I
VI
Terent'ev
D A
DA
Tomilin
N V
NV
Nasledov
G A
GA
D000818:Animals; D002478:Cells, Cultured; D004625:Embryo, Nonmammalian; D008564:Membrane Potentials / Q000502:physiology; D018482:Muscle, Skeletal / Q000166:cytology / Q000502:physiology*; D018408:Patch-Clamp Techniques; D015221:Potassium Channels / Q000502:physiology; D011896:Rana temporaria; D015222:Sodium Channels / Q000502:physiology; D013997:Time Factors
D015221:Potassium Channels; D015222:Sodium Channels
Formirovanie élektrovozbudimosti v kul'tiviruemykh émbrional'nykh miotsitakh liagushki.