title: Modern methods for probing RNA structure.
abstract: Molecular biologists have been remarkably successful in dividing large RNAs into small functional modules manageable for NMR and X-ray studies. At the same time biophysical, biochemical and genetic tools in RNA structure determination have reached a level of sophistication, at which we start to see a glimpse of molecular dynamics and the mechanism of RNA mediated catalysis.
authors.affiliation: Department of Molecular and Structural Biology, Aarhus University, Denmark. kjems@biobase.dk
authors.forename: J
authors.initials: J
authors.lastname: Kjems
authors.forename: J
authors.initials: J
authors.lastname: Egebjerg
mesh_terms: D001671:Biochemistry / Q000379:methods*; D001703:Biophysics / Q000379:methods*; D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D010802:Phylogeny; D012313:RNA / Q000737:chemistry* / Q000378:metabolism; D013816:Thermodynamics
chemical_list: D012313:RNA