Endothelial dysfunction and coronary risk reduction.
There is growing evidence that improvement of endothelial function has the potential to reduce cardiovascular ris. This article reviews the impact of coronary risk factors on endothelial function and the benefits of risk factor reduction. Recent studies indicate that chronic exercise may directly improve endothelial function, thus providing an additional explanation for the benefits of increased physical activity.
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Evans Memorial Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
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Vita
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D000208:Acute Disease; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000975:Antioxidants / Q000627:therapeutic use; D002908:Chronic Disease; D003327:Coronary Disease / Q000209:etiology* / Q000517:prevention & control*; D004730:Endothelium, Vascular / Q000187:drug effects / Q000503:physiopathology*; D015914:Estrogen Replacement Therapy; D015444:Exercise / Q000502:physiology; D006801:Humans; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D009569:Nitric Oxide / Q000502:physiology; D012307:Risk Factors
D000806:Angiotensin-Converting Enzyme Inhibitors; D000975:Antioxidants; D000960:Hypolipidemic Agents; D009569:Nitric Oxide