title: Malignant osteoclast-like giant cell tumor of the kidney.
abstract: Osteoclast-like giant cell tumors are rare mesenchymal tumors that typically present in osseous tissue and are remarkable because of their slow growth. We report the sixth documented case of a malignant osteoclast-like giant-cell tumor primary to the kidney of an 81-year-old man with a 5-month history of hematuria. Postnephrectomy analysis of the tumor, including immunohistochemical stains and electron microscopy, confirmed the diagnosis. Although the patient died of unrelated complications, metastatic disease was suspected.
authors.affiliation: Department of Urology and Pathology, The George Washington University Medical Center, Washington, DC 20037, USA.
authors.forename: K N
authors.initials: KN
authors.lastname: Heller
authors.forename: M J
authors.initials: MJ
authors.lastname: Manyak
authors.forename: S O
authors.initials: SO
authors.lastname: Tabbara
authors.forename: L A
authors.initials: LA
authors.lastname: Kerr
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005870:Giant Cell Tumors / Q000473:pathology*; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008297:Male