[Azithromycin in the prevention of Mediterranean spotted fever].
Antibodies to Rickettsia conorii were detected by the indirect immunofluorescence (IFA) assay in 64 (51.6%) out of 124 examinees living in North Dalmatia (Croatia) who had a history of recent tick bites during 1994 and 1995. Positive titers of IFA antibodies to R. conorii were detected in 12 (31.5%) out of 38 examinees with carried out prophylaxis by azithromycin. The usual clinical signs of Mediterranean spotted fever were registered in 22 (25.6%) and asymptomatic infection in 30 (34.8%) out of 86 examinees without prophylaxis. Clinical signs of the disease were not registered in examinees with prophylaxis.
Dzelalija
B
B
Sluzba za lijecenje zaraznih bolesti, Opća bolnica Zadar.
Morović
M
M
Avsic-Zupanc
T
T
D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D017963:Azithromycin / Q000627:therapeutic use*; D001907:Boutonneuse Fever / Q000517:prevention & control*; D002648:Child; D006801:Humans
D000900:Anti-Bacterial Agents; D017963:Azithromycin
Azitromicin u profilaksi mediteranske pjegave groznice.