title: Effects of housing conditions and 5-HT2A activation on male rat sexual behavior.
abstract: Adult male rats were housed individually or in groups for a period of 39 days. In Experiment 1, the effects of housing conditions on sexual behavior and concurrent spontaneous "wet dog shaking" (WDS) were investigated. Individual housing significantly impaired male sexual behavior and resulted in a trend toward increased WDS. In Experiment 2, the effects of housing conditions were examined following administration of the serotonergic type 2A (5-HT2A) agonist DOI. Individual housing significantly increased DOI-induced WDS. The implications of these findings are discussed in the context of stress-induced corticosterone secretion and the possible regulatory effect on 5-HT2A receptors.
authors.affiliation: Department of Psychology, The University of British Columbia, Vancouver, Canada.
authors.forename: L A
authors.initials: LA
authors.lastname: Brotto
authors.forename: B B
authors.initials: BB
authors.lastname: Gorzalka
authors.forename: L A
authors.initials: LA
authors.lastname: Hanson
mesh_terms: D000662:Amphetamines / Q000494:pharmacology; D000818:Animals; D006799:Housing, Animal; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D011985:Receptors, Serotonin / Q000187:drug effects / Q000502:physiology*; D017366:Serotonin Receptor Agonists / Q000494:pharmacology; D012726:Sexual Behavior, Animal / Q000502:physiology*; D012931:Social Environment; D012934:Social Isolation / Q000523:psychology
chemical_list: D000662:Amphetamines; D011985:Receptors, Serotonin; D017366:Serotonin Receptor Agonists; C015952:4-iodo-2,5-dimethoxyphenylisopropylamine