[Treatment review in rhinocerebral mucormycosis].
The rhinocerebral mucormycosis is the more common form produced by Rhizopus, a genus of fungi. It's a serious infective disease with high mortality, that needs a precocious medical treatment. Amphotericin B is the choice medical treatment, but liposomal amphotericine B in recent years is a better drug, due to minor renal toxicity and greater tisular diffusion. Even can not to treat all affected areas it's necessary an extensive surgical treatment according to individual characteristics and disease evolution. A 56-year-old man with rhinocerebral mucormycosis, caused by Rhizopus, who was treated with liposomal-amphotericin B and extensive rhino-orbital surgery is presented.
Pardal Refoyo
J L
JL
Hospital Virgen de la Concha, Insalud, Zamora.
Chocarro Martínez
A
A
Brezmes Valdivieso
M F
MF
Parra Pérez
C
C
D000666:Amphotericin B / Q000627:therapeutic use*; D000935:Antifungal Agents / Q000627:therapeutic use*; D001927:Brain Diseases / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000000981:diagnostic imaging / Q000382:microbiology / Q000628:therapy*; D010254:Paranasal Sinus Diseases / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery; D010256:Paranasal Sinuses / Q000000981:diagnostic imaging / Q000382:microbiology / Q000601:surgery*; D012233:Rhizopus / Q000302:isolation & purification; D014057:Tomography, X-Ray Computed
D000935:Antifungal Agents; D000666:Amphotericin B
Revisión del tratamiento en la mucormicosis rinocerebral.