Dendritic cells.
Dendritic cells are potent stimulators of immune responses against foreign antigens. Recent advances in this area include the delineation of distinct developmental pathways for different dendritic cell subsets; the emerging concept that one dendritic cell subset has regulatory functions that may contribute to induction of tolerance to self antigens; increased understanding of the interaction of dendritic cells with microbial products and viruses, such as HIV; and the application of dendritic cells for immunotherapy in certain cancers and possibly for the induction of transplantation tolerance.
Austyn
J M
JM
Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Headington, UK.
D000818:Animals; D003713:Dendritic Cells / Q000166:cytology* / Q000276:immunology*; D006801:Humans; D007167:Immunotherapy; D007801:Langerhans Cells / Q000276:immunology; D016393:Lymphoma, B-Cell / Q000628:therapy; D051379:Mice; D009369:Neoplasms / Q000628:therapy