The treatment of periocular and facial pain with topical capsaicin.
This article describes the effects of topically applied capsaicin (a nociceptive substance-P suppressor) in patients with neuropathic periocular or facial pain. Peripheral neuropathic pain is a major cause of periocular or facial discomfort and usually follows injury to a subcutaneous peripheral nerve. Though the damage is local, the pain tends to radiate. We studied three patients who complained of a 2- to 30-year history of fluctuating pain in the periocular area. All three had an area of point tenderness that responded to the topical application of capsaicin cream.
Lincoff
N S
NS
Department of Neurology and Ophthalmology, School of Medicine and Biomedical Sciences, State University of New York, Buffalo, USA.
Rath
P P
PP
Hirano
M
M
D000287:Administration, Topical; D000368:Aged; D002211:Capsaicin / Q000008:administration & dosage / Q000627:therapeutic use*; D005128:Eye Diseases / Q000188:drug therapy*; D005157:Facial Pain / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009824:Ointments; D010146:Pain / Q000188:drug therapy; D014277:Trigeminal Neuralgia / Q000188:drug therapy
D009824:Ointments; D002211:Capsaicin