title: Protective immune responses to Theileria annulata of relevance to vaccine development.
abstract: A series of projects on Theileria annulata funded by the European Union (STD1/STD2/STD3) have provided convincing evidence that macrophage and natural killer (NK) cell-dependent immune mechanisms may directly control the proliferation of different stages of T. annulata in cattle. The evidence for this conclusion and the implications for vaccine development are discussed in the following paper.
authors.affiliation: Division of Biological Sciences, University of Edinburgh, Scotland, U.K.
authors.forename: P M
authors.initials: PM
authors.lastname: Preston
authors.forename: A
authors.initials: A
authors.lastname: Visser
authors.forename: A
authors.initials: A
authors.lastname: Abraham
authors.forename: W
authors.initials: W
authors.lastname: Richardson
authors.forename: J
authors.initials: J
authors.lastname: Richardson
authors.forename: L
authors.initials: L
authors.lastname: Forsyth
authors.forename: L
authors.initials: L
authors.lastname: Bell-Sakyi
authors.forename: G
authors.initials: G
authors.lastname: Wilkie
authors.forename: G
authors.initials: G
authors.lastname: Entrican
authors.forename: R
authors.initials: R
authors.lastname: Boid
authors.forename: R L
authors.initials: RL
authors.lastname: Spooner
authors.forename: C G
authors.initials: CG
authors.lastname: Brown
mesh_terms: D000818:Animals; D000953:Antigens, Protozoan / Q000276:immunology; D002417:Cattle; D002418:Cattle Diseases / Q000276:immunology*; D007694:Killer Cells, Natural / Q000276:immunology; D008213:Lymphocyte Activation; D008262:Macrophage Activation / Q000276:immunology; D008264:Macrophages / Q000276:immunology; D016052:Protozoan Vaccines; D016796:Theileria annulata / Q000254:growth & development / Q000276:immunology*; D013801:Theileriasis / Q000276:immunology*
chemical_list: D000953:Antigens, Protozoan; D016052:Protozoan Vaccines