title: Divergent corticostriatal projections from a single cortical column in the somatosensory cortex of rats.
abstract: We injected biotinylated dextran amine (BDA) into single vibrissal 'barrels' of primary somatosensory (SI) cortex and reconstructed the topography of labelled varicosities in the dorsolateral caudate-putamen. Plots of labelled varicosities revealed densely-packed clusters of corticostriatal arborizations along the dorsolateral edge of the caudate-putamen and sparsely-packed arborizations more medially. The medial and lateral clusters of labelled terminals were separated by regions of unlabelled neuropil and lead us to conclude that a single cortical column sends divergent projections to multiple regions of the caudate-putamen.
authors.affiliation: Department of Neuroscience and Anatomy, Pennsylvania State University, Hershey, PA 17033, USA. kalloway@psuhmc.hmc.psu.edu
authors.forename: K D
authors.initials: KD
authors.lastname: Alloway
authors.forename: J J
authors.initials: JJ
authors.lastname: Mutic
authors.forename: J E
authors.initials: JE
authors.lastname: Hoover
mesh_terms: D000344:Afferent Pathways / Q000033:anatomy & histology / Q000502:physiology; D000818:Animals; D001370:Axonal Transport; D001710:Biotin / Q000031:analogs & derivatives; D001931:Brain Mapping; D002421:Caudate Nucleus / Q000033:anatomy & histology / Q000502:physiology*; D003911:Dextrans; D005456:Fluorescent Dyes; D011699:Putamen / Q000033:anatomy & histology / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013003:Somatosensory Cortex / Q000033:anatomy & histology / Q000502:physiology*; D014738:Vibrissae / Q000294:innervation*
chemical_list: D003911:Dextrans; D005456:Fluorescent Dyes; C076397:biotinylated dextran amine; D001710:Biotin