title: Towards development of T-cell vaccines.
abstract: Recent studies on the recognition of antigens by CD4+ and CD8+ T cells have revealed new ways of preparing efficient T-cell vaccines. Here, Constantin Bona and colleagues discuss several approaches for the development of T-cell vaccines, with applications ranging from the induction of protective immunity against intracellular parasites to the development of therapeutic agents against autoimmune disorders, allergic diseases and cancer.
authors.affiliation: Mount Sinai School of Medicine, Dept of Microbiology, New York, NY 10029, USA. bona@msvax.mssm.edu
authors.forename: C A
authors.initials: CA
authors.lastname: Bona
authors.forename: S
authors.initials: S
authors.lastname: Casares
authors.forename: T D
authors.initials: TD
authors.lastname: Brumeanu
mesh_terms: D000818:Animals; D004247:DNA / Q000276:immunology; D016503:Drug Delivery Systems; D018984:Epitopes, T-Lymphocyte / Q000276:immunology; D006801:Humans; D018448:Models, Immunological; D011994:Recombinant Proteins / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology; D014614:Vaccines, Synthetic / Q000276:immunology / Q000627:therapeutic use
chemical_list: D018984:Epitopes, T-Lymphocyte; D011994:Recombinant Proteins; D014614:Vaccines, Synthetic; D004247:DNA