Epidermolysis bullosa acquisita in childhood.
This case report of an 11-year-old girl describes a juvenile form of epidermolysis bullosa acquisita, an autoimmune disease of IgG antibodies to basement membrane type 7 collagen. Our case illustrates an unusually severe, acute inflammatory presentation of this condition with prominent mucosal and constitutional features requiring admission to a paediatric burns unit. The treatment consisted of supportive topical and systemic agents, prednisolone and dapsone. She responded to dapsone alone and the course of the illness was uneventful.
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J C
JC
Department of Dermatology, Royal Children's Hospital, Parkville, Victoria, Australia.
Varigos
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GA
Dowling
J
J
D000890:Anti-Infective Agents / Q000627:therapeutic use; D002648:Child; D003622:Dapsone / Q000627:therapeutic use; D016107:Epidermolysis Bullosa Acquisita / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006801:Humans
D000890:Anti-Infective Agents; D003622:Dapsone