title: EEG findings in diabetic patients with and without retinopathy.
abstract: OBJECTIVE
  We showed previously that temporal low-voltage irregular delta waves (TLID) on EEG are indicative of cerebrovascular dysfunction in its early stages. The present study was designed to determine whether the incidence of this finding is elevated in diabetics as compared to normal controls.
  
  
  METHODS
  EEGs of 50 diabetics and 50 normal controls were examined. Relationships of blood sugar levels, levels of HbA1C and stages of diabetic retinopathy to TLID were also examined.
  
  
  RESULTS
  TLID was found in 56% of EEGs of the diabetics and in 14% of EEGs of the controls (P < 0.0001). The occurrence of TLID was also associated with the presence of diabetic retinopathy.
  
  
  CONCLUSIONS
  Our results suggest that the incidence of cerebrovascular dysfunction is elevated in diabetics. Since TLID was associated with diabetic retinopathy, it seems possible that the TLID detected in diabetics might reflect certain functional changes induced by microangiopathy of the brain.
authors.affiliation: Department of Psychiatry, Mie University School of Medicine, Tsu, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Inui
authors.forename: H
authors.initials: H
authors.lastname: Sannan
authors.forename: H
authors.initials: H
authors.lastname: Ota
authors.forename: Y
authors.initials: Y
authors.lastname: Uji
authors.forename: S
authors.initials: S
authors.lastname: Nomura
authors.forename: H
authors.initials: H
authors.lastname: Kaige
authors.forename: I
authors.initials: I
authors.lastname: Kitayama
authors.forename: J
authors.initials: J
authors.lastname: Nomura
mesh_terms: D000328:Adult; D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D002540:Cerebral Cortex / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000175:diagnosis* / Q000503:physiopathology; D003925:Diabetic Angiopathies / Q000175:diagnosis* / Q000503:physiopathology; D003930:Diabetic Retinopathy / Q000175:diagnosis* / Q000503:physiopathology; D004569:Electroencephalography; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin