title: Effects of anesthetics on Fos protein expression in autonomic brain nuclei related to cardiovascular regulation.
abstract: We tested the influence of urethane, chloral hydrate and a mixture of ketamine/xylazine on Fos protein expression in autonomic brain regions related to blood pressure. We conclude that ketamine/xylazine is a suitable anesthetic to be used in studies looking at c-fos expression in neural circuits serving cardiovascular regulation.
authors.affiliation: Department of Physiology, University of Tübingen, Germany. mjrocha@rfi.fmrp.usp.br
authors.forename: M J
authors.initials: MJ
authors.lastname: Rocha
authors.forename: H
authors.initials: H
authors.lastname: Herbert
mesh_terms: D000777:Anesthetics / Q000494:pharmacology*; D018681:Anesthetics, General / Q000494:pharmacology; D000818:Animals; D001341:Autonomic Nervous System / Q000187:drug effects / Q000378:metabolism*; D001921:Brain / Q000033:anatomy & histology / Q000187:drug effects / Q000502:physiology*; D002697:Chloral Hydrate / Q000494:pharmacology; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology*; D007150:Immunohistochemistry; D007649:Ketamine / Q000494:pharmacology; D008297:Male; D016760:Proto-Oncogene Proteins c-fos / Q000096:biosynthesis*; D051381:Rats; D017207:Rats, Sprague-Dawley; D014520:Urethane / Q000494:pharmacology; D014991:Xylazine / Q000494:pharmacology
chemical_list: D000777:Anesthetics; D018681:Anesthetics, General; D016760:Proto-Oncogene Proteins c-fos; D014991:Xylazine; D014520:Urethane; D002697:Chloral Hydrate; D007649:Ketamine