[Peptide modulation of vagal sinus arrhythmia in cats].
In anesthetised cats, following vagal stimulation with short bursts of pulses, a narrow zone was identified within the cardiac cycle where even a small change of the vagal burst position produced sharp alterations in the magnitude of the chronotropic effect. Somatostatin diminished the size of this zone whereas its antagonist exerted an opposite effect.
Osadchiĭ
O E
OE
Kuban' Medical Academy, Krasnodar, Russia.
Pokrovskiĭ
V M
VM
D000818:Animals; D001146:Arrhythmia, Sinus / Q000503:physiopathology*; D002415:Cats; D004558:Electric Stimulation; D004562:Electrocardiography; D004743:Enkephalin, Leucine / Q000494:pharmacology*; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology; D006339:Heart Rate / Q000187:drug effects; D006727:Hormone Antagonists / Q000494:pharmacology*; D013004:Somatostatin / Q000031:analogs & derivatives* / Q000037:antagonists & inhibitors / Q000494:pharmacology*; D013997:Time Factors; D014630:Vagus Nerve / Q000187:drug effects*
D006727:Hormone Antagonists; D013004:Somatostatin; D004743:Enkephalin, Leucine; C043820:cyclo(7-aminoheptanoylphenylalanyl-tryptophyl-lysyl-benzylthreonyl)
Peptidnaia moduliatsiia vagusnoĭ sinusovoĭ aritmii serdtsa u koshek.