title: Intermale aggression, GAD activity in the olfactory bulbs and Y chromosome effect in seven inbred mouse strains.
abstract: The capacity to attack a passive standard opponent in a resident-intruder test and the GAD activity in the olfactory bulbs were measured in 140 male mice from seven different inbred mouse strains. The effect of the non-pseudo autosomal region of the Y-chromosome (YNPAR) on these two phenotypes has also been investigated using a quartet of reciprocal strains congenic for the YNPAR. A strong negative correlation was found between the two variables but the YNPAR is not involved. This result suggests that males of more attacking strains have a lower olfactory threshold, making the olfactory discrimination of the opponent easier and its identification as a stranger more efficient.
authors.affiliation: Mammalian Genetics Unit, Medical Research Council, Harwell, Didcot, Oxfordshire, UK. P.GUILLOT@har.mrc.ac.uk
authors.forename: P V
authors.initials: PV
authors.lastname: Guillot
authors.forename: G
authors.initials: G
authors.lastname: Chapouthier
mesh_terms: D000374:Aggression / Q000502:physiology*; D000818:Animals; D005969:Glutamate Dehydrogenase / Q000378:metabolism*; D007700:Kinetics; D008297:Male; D051379:Mice; D008815:Mice, Inbred Strains; D009830:Olfactory Bulb / Q000201:enzymology*; D013045:Species Specificity; D014998:Y Chromosome / Q000201:enzymology*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism
chemical_list: D005680:gamma-Aminobutyric Acid; D005969:Glutamate Dehydrogenase