title: Synthesis and conformational analysis of two 2-oxopiperazine-containing tetrapeptide analogues.
abstract: One unsubstituted and one stereoselectively prepared 3-(S)-substituted-2-oxopiperazine have been used as dipeptide templates to generate tetrapeptide analogues. NMR analysis shows that these tetrapeptide analogues present an inverse gamma-turn conformation in chloroform.
authors.affiliation: Laboratoire de Chimie Thérapeutique, Faculté des Sciences Pharmaceutiques et Biologiques, Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Pohlmann
authors.forename: D
authors.initials: D
authors.lastname: Guillaume
authors.forename: J C
authors.initials: JC
authors.lastname: Quirion
authors.forename: H P
authors.initials: HP
authors.lastname: Husson
mesh_terms: D000478:Alkylation; D002725:Chloroform; D004151:Dipeptides; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D009842:Oligopeptides / Q000138:chemical synthesis* / Q000737:chemistry; D010879:Piperazines / Q000737:chemistry*; D011487:Protein Conformation; D013698:Templates, Genetic
chemical_list: D004151:Dipeptides; D009842:Oligopeptides; D010879:Piperazines; D002725:Chloroform