title: Appearance of electron spin resonance signals in the interaction of dithiocarbamate-Fe(II) with nitrogen dioxide and nitrite.
abstract: Whether dithiocarbamate-Fe(II) complexes used in the electron spin resonance (ESR) studies are specific for the detection of NO was investigated. It was found that the typical ESR signals of dithiocarbamate-Fe(II)-NO spin adducts appeared in the interaction of N-methyl-D-glucaminedithiocarbamate (MGD)-, bis(hydroxyethyl) dithiocarbamate (HED)- and diethyldithiocarbamate (DED)-Fe(II) complexes with the NO-derived nitrogen oxides, nitrogen dioxide (NO2) and nitrite ion (NO2-) in a prolonged incubation. Under the conditions of prolonged incubation, appearance of the ESR signals of the dithiocarbamate-Fe(II)-NO spin adducts may indicate the presence of not only NO but NO2 and NO2-.
authors.affiliation: School of Pharmacy, Tokyo University of Pharmacy and Life Science, Hachioji, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Hiramoto
authors.forename: S
authors.initials: S
authors.lastname: Tomiyama
authors.forename: K
authors.initials: K
authors.lastname: Kikugawa
mesh_terms: D002614:Chelating Agents / Q000737:chemistry; D004050:Ditiocarb / Q000031:analogs & derivatives / Q000737:chemistry / Q000378:metabolism; D004578:Electron Spin Resonance Spectroscopy; D005296:Ferrous Compounds / Q000737:chemistry / Q000378:metabolism*; D009573:Nitrites / Q000737:chemistry / Q000378:metabolism*; D009585:Nitrogen Dioxide / Q000737:chemistry / Q000378:metabolism*; D009609:Nitrous Oxide / Q000737:chemistry / Q000378:metabolism; D012996:Solutions; D013012:Sorbitol / Q000031:analogs & derivatives* / Q000737:chemistry / Q000378:metabolism; D013113:Spin Labels; D013859:Thiocarbamates / Q000737:chemistry / Q000378:metabolism*
chemical_list: D002614:Chelating Agents; D005296:Ferrous Compounds; D009573:Nitrites; D012996:Solutions; D013113:Spin Labels; D013859:Thiocarbamates; C110934:dithiocarbamate-Fe(II); D013012:Sorbitol; C041262:N-methyl-D-glucamine dithiocarbamate; D004050:Ditiocarb; C039353:dihydroxyethyldithiocarbamate; D009609:Nitrous Oxide; D009585:Nitrogen Dioxide