Divergent corticostriatal projections from a single cortical column in the somatosensory cortex of rats.
We injected biotinylated dextran amine (BDA) into single vibrissal 'barrels' of primary somatosensory (SI) cortex and reconstructed the topography of labelled varicosities in the dorsolateral caudate-putamen. Plots of labelled varicosities revealed densely-packed clusters of corticostriatal arborizations along the dorsolateral edge of the caudate-putamen and sparsely-packed arborizations more medially. The medial and lateral clusters of labelled terminals were separated by regions of unlabelled neuropil and lead us to conclude that a single cortical column sends divergent projections to multiple regions of the caudate-putamen.
Alloway
K D
KD
Department of Neuroscience and Anatomy, Pennsylvania State University, Hershey, PA 17033, USA. kalloway@psuhmc.hmc.psu.edu
Mutic
J J
JJ
Hoover
J E
JE
D000344:Afferent Pathways / Q000033:anatomy & histology / Q000502:physiology; D000818:Animals; D001370:Axonal Transport; D001710:Biotin / Q000031:analogs & derivatives; D001931:Brain Mapping; D002421:Caudate Nucleus / Q000033:anatomy & histology / Q000502:physiology*; D003911:Dextrans; D005456:Fluorescent Dyes; D011699:Putamen / Q000033:anatomy & histology / Q000502:physiology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013003:Somatosensory Cortex / Q000033:anatomy & histology / Q000502:physiology*; D014738:Vibrissae / Q000294:innervation*
D003911:Dextrans; D005456:Fluorescent Dyes; C076397:biotinylated dextran amine; D001710:Biotin