A murine specific splicing variant of the acetylcholine receptor epsilon-subunit gene transcript.
The acetylcholine receptor (AChR) is an ion channel involved in signal transmission from motorneuron to skeletal muscle. We describe here a murine-specific splicing variant of the epsilon subunit of the AChR (epsilon s), which lacks exon 5 epsilon s has a truncated extracellular domain which may affect the physiological characteristics of the resulting AChR channel.
Koishi
K
K
Department of Anatomy and Structural Biology, University of Otago Medical School, Dunedin, New Zealand. kyoko.koishi@stonebow.otago.ac.nz
McLennan
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D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D018076:DNA, Complementary / Q000235:genetics; D051379:Mice; D008969:Molecular Sequence Data; D018482:Muscle, Skeletal / Q000737:chemistry; D009928:Organ Specificity; D012326:RNA Splicing / Q000235:genetics*; D012333:RNA, Messenger / Q000032:analysis / Q000235:genetics*; D011950:Receptors, Cholinergic / Q000235:genetics*; D017422:Sequence Analysis, DNA
D018076:DNA, Complementary; D012333:RNA, Messenger; D011950:Receptors, Cholinergic