A case of Wegener's granulomatosis complicated by diffuse pulmonary hemorrhage and thrombotic thrombocytopenic purpura.
Wegener's granulomatosis is a distinct form of necrotizing granulomatous vasculitis which usually affects the kidneys and the upper and lower respiratory tracts. Unusual manifestations have also been reported, and these include colitis, urethritis and diabetes insipidus. We describe a case of Wegener's granulomatosis which presented with rapidly progressive renal insufficiency, sudden deafness, red eye, facial palsy, and complicated by uncommon manifestations that were diffuse pulmonary hemorrhage and thrombotic thrombocytopenic purpura.
Lim
H E
HE
Department of Internal Medicine and Clinical Pathology, College of Medicine, Korea University, Seoul, Korea.
Jo
S K
SK
Kim
S W
SW
Choi
H K
HK
Suh
I B
IB
Yoon
S Y
SY
Moon
J S
JS
Won
N H
NH
Kwon
Y J
YJ
Pyo
H J
HJ
D000368:Aged; D016572:Cyclosporine / Q000627:therapeutic use; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006470:Hemorrhage / Q000150:complications*; D006801:Humans; D008171:Lung Diseases / Q000150:complications*; D011239:Prednisolone / Q000627:therapeutic use; D011697:Purpura, Thrombotic Thrombocytopenic / Q000150:complications*
D016572:Cyclosporine; D011239:Prednisolone