title: [Application of electron microscopy and immunohistochemistry to the study of malignant tumors: a review of their diagnostic importance].
abstract: The results of examining in the course of the past twenty years a considerable number of malignant tumors with transmission electron microscopy and immunohistochemistry are discussed. The neoplasms were divided into epithelial tumors, tumors of fusiform cells, malignant round cell tumors and tumors of endocrine nature. The main ultrastructural findings and the results of immunohistochemical studies were pointed out regarding their contributory role in the diagnosis as well as for the prognosis and treatment of patients with cancer.
authors.affiliation: Unidad de Investigación en Patología Ultraestructural y Biología Molecular, Facultad de Medicina, Universidad Central de Venezuela, Caracas, Venezuela.
authors.forename: J
authors.initials: J
authors.lastname: García-Tamayo
authors.forename: E
authors.initials: E
authors.lastname: Caleiras
authors.forename: E
authors.initials: E
authors.lastname: Blasco-Olaetxea
authors.forename: D
authors.initials: D
authors.lastname: Parada
authors.forename: S E
authors.initials: SE
authors.lastname: de García
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D005069:Evaluation Studies as Topic; D006801:Humans; D007150:Immunohistochemistry; D008854:Microscopy, Electron; D009369:Neoplasms / Q000737:chemistry / Q000145:classification / Q000175:diagnosis* / Q000648:ultrastructure; D012189:Retrospective Studies
chemical_list: D014408:Biomarkers, Tumor
vernacular_title: Aplicación de la microscopía electrónica y de la inmunohistoquímica a1 estudio de los tumores malignos: una revisión de su importancia diagnóstica.