title: Transmissible spongiform encephalopathies in food animals. Human food safety and animal feed safety concerns for veterinarians.
abstract: This article presents a brief overview of transmissible spongiform encephalopathies (TSEs) using examples of diseases that provide evidence supporting oral transmission of the agent. Agent theories are described briefly in general terms. Scrapie, bovine spongiform encephalopathy (BSE), chronic wasting disease, and transmissible mink encephalopathy are discussed to improve disease recognition by the food animal practitioner. Control programs for scrapie and BSE are described and the role of the veterinarian in animal feed and human food safety is related to TSEs.
authors.affiliation: Center for Veterinary Medicine, United States Food and Drug Administration, Rockville, Maryland, USA.
authors.forename: K A
authors.initials: KA
authors.lastname: Godon
authors.forename: J
authors.initials: J
authors.lastname: Honstead
mesh_terms: D000821:Animal Feed / Q000592:standards; D000818:Animals; D002417:Cattle; D007562:Creutzfeldt-Jakob Syndrome / Q000209:etiology*; D016643:Encephalopathy, Bovine Spongiform / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D005523:Food Supply / Q000592:standards; D015511:Goat Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D006041:Goats; D006801:Humans; D018620:PrPSc Proteins / Q000737:chemistry; D017096:Prion Diseases / Q000209:etiology / Q000635:transmission*; D011328:Prions / Q000502:physiology; D012608:Scrapie / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D012756:Sheep
chemical_list: D018620:PrPSc Proteins; D011328:Prions