title: [Local progression of atherosclerosis after optimal directional atherectomy. Endocoronary ultrasonography of 17 patients].
abstract: In vivo endovascular ultrasonography has confirmed the extension of atheroma to angiographically normal segments. The authors set out to determine by endocoronary ultrasonography if the introduction of the atherotome changed the intimal thickness 20 mm proximal and distal to the site treated. The area circumscribed by the external elastic layer (EEL) and the surface area of the lumen was measured in 17 patients: 1) before atherectomy; 2) after atherectomy; 3) at control 6 months later. Atherectomy immediately increased the luminal area at the site dilated from 1.9 + 0.9 to 8.1 +/- 2mm (p < 0.001). At the proximal segment, the surface area of the lumen was unchanged (mean + 0.6 +/- 1.5 mm2; p = 0.13). Similarly the procedure did not change the surface circumscribed by the EEL (mean + 0.8 +/- 3.2 mm2; p = 0.32) in this zone. The same results were observed at the distal site. At 6 months, the areas under the EEL and those of the lumen were unchanged at the unoperated sites. The mean of the differences (+/- 1 SD) for the area under the EEL was respectively -0.2 +/- 1.5 mm2 proximally and +0.7 +/- 2.5 mm2 distally. The means for the luminal area were 0.2 +/- 1 mm2 proximally and -0.01 +/- 1.1 mm2; distally. At the site of atherectomy, the luminal surface increased (+2.0 +/- 2.6 mm2; p < 0.01) as did the area under the EEL (+2.0 +/- 3.5 mm2; p < 0.05). This preliminary series shows no significant progression of atherosclerosis at the sites not affected by atherectomy.
authors.affiliation: Service de soins intensifs et de cardiologie interventionelle, Université de Bordeaux II.
authors.forename: P
authors.initials: P
authors.lastname: Coste
authors.forename: S
authors.initials: S
authors.lastname: Sempé
authors.forename: C
authors.initials: C
authors.lastname: Jaïs
authors.forename: P
authors.initials: P
authors.lastname: Dos Santos
authors.forename: B
authors.initials: B
authors.lastname: Bonoron-Adèle
authors.forename: F
authors.initials: F
authors.lastname: Duclos
authors.forename: R
authors.initials: R
authors.lastname: Roudaut
authors.forename: P
authors.initials: P
authors.lastname: Besse
mesh_terms: D000328:Adult; D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D017225:Atherectomy, Coronary / Q000379:methods* / Q000706:statistics & numerical data; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000601:surgery; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D012008:Recurrence; D018084:Ultrasonography, Interventional / Q000379:methods* / Q000706:statistics & numerical data
vernacular_title: Progression locale de l'athérosclérose après athérectomie directionnelle optimale. Analyse par échographie endovasculaire à propos de 17 patients.