A resected case of Mycobacterium szulgai pulmonary disease.
We present the first reported case of Mycobacterium szulgai pulmonary disease that needed surgical resection due to unsuccessful antimycobacterial chemotherapy. The patient was a non-immunocompromised 48-year-old male who presented with hemoptysis and whose sputum cultures repeatedly yielded M. szulgai. Antimycobacterial chemotherapy with isoniazid (INH) and rifampin (RMP)/ethambutol (EMB) for three years had been unsuccessful, and subsequent chemotherapy with RMP, EMB, ethionamide and kanamycin had to be discontinued due to liver dysfunction. Surgical resection was finally performed, and resulted in a favorable outcome. Although M. szulgai pulmonary disease is usually well controlled by antimycobacterial chemotherapy alone, surgical treatment may be necessary in some cases.
Tsuyuguchi
K
K
Department of Infection and Inflammation, Chest Disease Research Institute, Kyoto University, Japan.
Amitani
R
R
Matsumoto
H
H
Tanaka
E
E
Suzuki
K
K
Yanagihara
K
K
Mizuno
H
H
Hitomi
S
S
Kuze
F
F
D000995:Antitubercular Agents / Q000008:administration & dosage / Q000009:adverse effects; D004359:Drug Therapy, Combination; D004977:Ethambutol / Q000008:administration & dosage / Q000009:adverse effects; D005000:Ethionamide / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D007538:Isoniazid / Q000008:administration & dosage; D007612:Kanamycin / Q000008:administration & dosage / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy / Q000601:surgery*; D012293:Rifampin / Q000008:administration & dosage; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy / Q000601:surgery*
D000995:Antitubercular Agents; D007612:Kanamycin; D004977:Ethambutol; D005000:Ethionamide; D007538:Isoniazid; D012293:Rifampin