The genetics of epigenetics.
The formation of silent epialleles is accompanied by local hypermethylation of the DNA template, and genetically altered, methylation-deficient Arabidopsis mutants generate an increased number of epimutations. But what came first - methylation or epigenetic change?
Paszkowski
J
Friedrich Miescher Institute PO Box 2543, Ch 4002, Basel, Switzerland jurek@fmi.ch
Scheid
OM