[Eruptive melanocytic nevi after chemotherapy].
BACKGROUND
Induction of melanocytic naevi by chemotherapy in children is reported in the literature. The reason for this phenomenon is not known yet.


METHODS
We present a 6-year-old girl who fell ill with acute lymphoblastic leukemia at the age of 2 years. After a combined chemotherapeutic treatment for 2 years followed by complete remission of leukemia, many (> 100) small pigmented naevi appeared over the whole body. The naevi did not show features suggestive of dysplasia.


CONCLUSIONS
Patients with excess numbers of melanocytic naevi constitute a risk group for malignant melanoma, therefore periodic skin examination is recommended.
Karrer
S
S
Dermatologische Klinik und Poliklinik, Universität Regensburg.
Szeimies
R M
RM
Stolz
W
W
Landthaler
M
M
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D005260:Female; D006801:Humans; D009508:Nevus, Pigmented / Q000139:chemically induced* / Q000235:genetics; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*; D012074:Remission Induction; D012878:Skin Neoplasms / Q000139:chemically induced* / Q000235:genetics
Eruptive melanozytäre Nävi nach Chemotherapie.