Parachordoma: a rare sarcoma with clonal chromosomal changes.
This is the first report on clonal chromosomal aberrations in a metastatic parachordoma lesion. All neoplastic cells had the karyotype 33-47,X,der(X)t(X;3) (p11;p11),der(3)t(3;6)(p11;q13), del(6)(q13), -9, -13,r(13), +mar. The presence of t(X;3) with a breakpoint at band Xp11 as in synovial sarcoma may suggest a common histological origin of the two tumor types.
Limon
J
J
Department of Biology and Genetics, Medical University of Gdańsk, Poland.
Babińska
M
M
Denis
A
A
Ryś
J
J
Niezabitowski
A
A
D002817:Chordoma / Q000235:genetics* / Q000473:pathology; D002869:Chromosome Aberrations; D005260:Female; D006801:Humans; D007621:Karyotyping; D008207:Lymphatic Metastasis; D008875:Middle Aged; D013899:Thoracic Neoplasms / Q000235:genetics / Q000473:pathology