Primary cerebellar nocardiosis and alveolar proteinosis.
We report a patient with known asymptomatic pulmonary alveolar proteinosis (PAP) who developed a cerebellar gait disorder and dysarthria caused by an isolated cerebellar nocardial abscess. To our knowledge only 1 patient with PAP and isolated central nervous system nocardia infection has previously been reported. In this early report, diagnosis was established at autopsy. In our patient the clinical and MRI examinations of this cerebellar abscess are described and specific features leading to earlier diagnosis and successful treatment are presented.
Oerlemans
W G
WG
Department of Neurology, Hospital Medisch Spectrum, Enschede, The Netherlands.
Jansen
E N
EN
Prevo
R L
RL
Eijsvogel
M M
MM
D001922:Brain Abscess / Q000175:diagnosis* / Q000473:pathology; D002526:Cerebellar Diseases / Q000175:diagnosis* / Q000473:pathology; D002531:Cerebellum / Q000473:pathology; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D009617:Nocardia Infections / Q000175:diagnosis* / Q000473:pathology; D011649:Pulmonary Alveolar Proteinosis / Q000175:diagnosis* / Q000473:pathology