[HIV infection and pericardial disease invasion in Africa].
The number of cases with pericardial disease has been increasing in Africa and particularly in Zäire, after AIDS was defined. To investigate a possible link between HIV infection and risen incidence of pericardial effusions, 64 patients randomly selected (32 HIV carriers and 32 HIV-seronegative as controls), with suspected pericardial disease were studied in a longitudinal trial from January 1991 to December 1994. Central and accessory cells of immune system were measured in conjunction with blood screening, electrocardiogram (ECG), chest X-ray and cardiac ultrasound. Haematological examination included also microscopical examination of blood films after May-Grünwald-Giemsa staining. There were significant decreases of hemoglobin, CD4 cells, and basophils in HIV-seropositive patients. Pericardial disease was estimated 8.8% of in-hospital prevalence, in which 70% of cases were related to HIV infection. The HIV related pericardial disease had an incidence of 1.8% per year. Etiology of pericardial disease depends on evolution and immunodepression level; 90.5% of pericardial effusions related to HIV are caused by tuberculosis as shown at the second pericardiocenthesis.
Longo-Mbenza
B
B
Centre de cardiologie du coeur de l'Afrique, Kinshasa-Limete, Zaïre.
Tonduangu
K
K
Seghers
K V
KV
Mubagwa
D
D
D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000453:epidemiology; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000453:epidemiology; D000206:Actuarial Analysis; D000328:Adult; D000349:Africa / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D010493:Pericarditis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D010495:Pericarditis, Tuberculous / Q000453:epidemiology / Q000209:etiology; D011379:Prognosis; D012514:Sarcoma, Kaposi / Q000150:complications / Q000453:epidemiology; D015996:Survival Rate
Irruption de l'infection par le VIH et des pèricardites en Afrique.