title: [Suction pump-supported aspiration thrombectomy: an in-vitro comparison with a thrombus fragmentation procedure].
abstract: OBJECTIVE
  To compare the efficacy of vacuum pump controlled aspiration thrombectomy (VPCAT) with the Amplatz thrombectomy device (ATD) for treatment of thrombotic occlusions.
  
  
  METHODS
  In a flow-model a superficial femoral artery is simulated. VPCAT provides the connection either of an aspiration catheter (AC, 8 F) or a multipurpose catheter (MPC, 8 F) with a vacuum pump (-110 mbar underpressure). 7 day old porcine blood (n = 30; 7.4 g +/- 0.1g) was treated with AC and MPC (VPCAT technique) and with the ATD.
  
  
  RESULTS
  Complete thrombectomy was achieved with all techniques. Thrombectomy time was short for ATD (8.8 +/- 0.94 s; p < 0.01). MPC caused the least overall weight of emboli related to thrombus weight (5.14 0/100; p < 0.01). ATD caused the least embolisms at 1000 microns (3.27 mg; p < 0.05), and the most embolisms at 100 microns and at 10 microns (26.5 mg and 26.9 mg; p < 0.01). The aspirated volume of the MPC (33 +/- 17 ml) was half the volume of the AC (65 +/- 25 ml).
  
  
  CONCLUSIONS
  In-vitro, VPCAT proves to be an alternative procedure to ATD. The use of a wide lumen multipurpose catheter is advantageous. In vitro, embolism rates of all methods are sufficiently low.
authors.affiliation: Klinik für Radiologische Diagnostik, Christian-Albrechts-Universität zu Kiel.
authors.forename: S
authors.initials: S
authors.lastname: Müller-Hülsbeck
authors.forename: H
authors.initials: H
authors.lastname: Schwarzenberg
authors.forename: C
authors.initials: C
authors.lastname: Bangard
authors.forename: J C
authors.initials: JC
authors.lastname: Steffens
authors.forename: M
authors.initials: M
authors.lastname: Heller
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D002404:Catheterization; D005069:Evaluation Studies as Topic; D005263:Femoral Artery; D005374:Filtration / Q000295:instrumentation; D066298:In Vitro Techniques; D013396:Suction / Q000295:instrumentation; D013552:Swine; D017131:Thrombectomy / Q000295:instrumentation* / Q000379:methods / Q000706:statistics & numerical data; D013927:Thrombosis / Q000628:therapy; D014618:Vacuum
vernacular_title: Saugpumpenunterstützte Aspirationsthrombektomie: In-vitro-Vergleich mit einem Thrombusfragmentierungsverfahren.