Detrimental effects of polyvinylpyrrolidone on the ultrastructure of spermatozoa (Notulae seminologicae 13).
The effect of in-vitro treatment by polyvinylpyrrolidone (PVP) on the ultrastructure of human spermatozoa has been tested previously with the statistical analysis of B. Baccetti et al. (1995, J. Androl., 16, 356-371). PVP had a primary detrimental action on the plasma membrane, as well as on acrosomal and mitochondrial membranes. Furthermore, membrane damage induces deterioration of the chromatin, axonemal tubules, fibrous sheath, and accessory fibres.
Strehler
E
E
Institute for Reproductive Medicine, Ulm, Germany.
Baccetti
B
B
Sterzik
K
K
Capitani
S
S
Collodel
G
G
De Santo
M
M
Gambera
L
L
Piomboni
P
P
D000177:Acrosome / Q000187:drug effects; D002462:Cell Membrane / Q000187:drug effects; D002467:Cell Nucleus / Q000187:drug effects; D006801:Humans; D008297:Male; D008928:Mitochondria / Q000187:drug effects; D011205:Povidone / Q000009:adverse effects*; D013094:Spermatozoa / Q000187:drug effects* / Q000648:ultrastructure
D011205:Povidone