title: Long-term remission of two feet-one hand syndrome.
abstract: Two feet-one hand syndrome is also defined as bilateral plantar tinea pedis with coexistent unilateral tinea manuum. Toenails and fingernails may also be affected and the dermatophyte Trichophyton rubrum is the usual cause. When there is nail involvement, especially of the toenails, treatment with an oral antifungal agent should be considered because topical therapy alone is usually not effective. However, relapses are common. With the advent of new, more effective antifungal drugs such as itraconazole, terbinafine, and fluconazole, it is hoped that this troublesome and recalcitrant disorder may be better controlled.
authors.affiliation: Department of Dermatology, Columbia-Presbyterian Medical Center, New York, New York 10032, USA.
authors.forename: J
authors.initials: J
authors.lastname: Seeburger
authors.forename: R K
authors.initials: RK
authors.lastname: Scher
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D006229:Hand Dermatoses / Q000188:drug therapy; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use*; D008297:Male; D014009:Onychomycosis / Q000188:drug therapy*; D013577:Syndrome; D014008:Tinea Pedis / Q000188:drug therapy*; D014249:Trichophyton / Q000302:isolation & purification*
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole