title: Influence of thoracic conformation and genetics on the risk of gastric dilatation-volvulus in Irish setters.
abstract: Body measurements, history of gastric dilatation-volvulus (GDV), and other data were obtained for 155 Irish setters at the 1994 National Specialty Show. The dogs ranged in age from 6.5 months to 12.4 years (mean+/-standard deviation [SD], 3.6+/-2.6 years); 11 (7%) of the dogs had histories of GDV. Gastric dilatation-volvulus risk increased 33% for each year of age (p of 0.01). Dogs with the deepest thorax relative to width (ratio range, 1.61 to 1.85) had a significantly greater GDV risk than those with the shallowest thorax (ratio range, 1.20 to 1.50); the odds ratio was 8.45; the 95% confidence limits were 1.44 to 49.57; and the p value equaled 0.02. Having a relative (particularly a parent) with GDV also increased GDV risk. Five-generation pedigrees yielded a significantly higher mean coefficient of relationship for the 11 dogs with GDV than for the 11 dogs without GDV.
authors.affiliation: Department of Veterinary Pathobiology, School of Veterinary Medicine, Purdue University, West Lafayette, Indiana 47907-1243, USA.
authors.forename: D
authors.initials: D
authors.lastname: Schellenberg
authors.forename: Q
authors.initials: Q
authors.lastname: Yi
authors.forename: N W
authors.initials: NW
authors.lastname: Glickman
authors.forename: L T
authors.initials: LT
authors.lastname: Glickman
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000453:epidemiology / Q000235:genetics; D004285:Dogs / Q000033:anatomy & histology* / Q000235:genetics; D005260:Female; D013271:Gastric Dilatation / Q000453:epidemiology / Q000503:physiopathology / Q000662:veterinary*; D008297:Male; D010375:Pedigree; D012307:Risk Factors; D012727:Sex Characteristics; D013045:Species Specificity; D013277:Stomach Volvulus / Q000453:epidemiology / Q000503:physiopathology / Q000662:veterinary*; D013909:Thorax / Q000033:anatomy & histology*