title: Otolaryngologic manifestations of gastro-oesophageal reflux disease.
abstract: At present, gastro-oesophageal reflux disease (GORD) is believed to be an important contributing etiologic factor in many laryngopharyngeal disorders. Endoscopic oesophagitis, however, is found in less than 25% of these patients. Prolonged oesophageal pH monitoring with a dual pH probe is the most sensitive test for diagnosing GORD-related ear, nose and throat (ENT) problems. Based on the therapy studies one may recommend the use of, preferably, proton-pump inhibitors in higher doses than in typical GORD patients. Therapy may be necessary for prolonged intervals or for a lifetime.
authors.affiliation: Dept of Gastroenterology, Free University Hospital, Amsterdam, The Netherlands.
authors.forename: E C
authors.initials: EC
authors.lastname: Klinkenberg-Knol
mesh_terms: D003680:Deglutition Disorders / Q000175:diagnosis / Q000209:etiology; D004941:Esophagitis / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D004945:Esophagoscopy; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000628:therapy*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis / Q000209:etiology; D007828:Laryngoscopy; D010038:Otorhinolaryngologic Diseases / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy