title: Rhizopus microsporus in wooden tongue depressors: a major threat or minor inconvenience?
abstract: The investigation and management of an apparent outbreak of Rhizopus spp. in a London paediatric referral centre between September 1995 and April 1996 is described. The organism was identified in microbiological surveillance samples from 23 patients nursed in four hospital areas. Investigations revealed the presence of the organism in spatulae from all ward areas investigated and from closed boxed containers held in the central hospital stores obtained from a new supplier. In contrast, culture of spatulae from the initial supplier failed to yield any fungal isolates. The incident was reported to the Medical Device Agency (MDA), the Central Public Health Laboratory Service (CPHLS) and the Birmingham PHLS. A statement was prepared for the weekly Communicable Disease Report and a hazard warning issued by the MDA. The spatulae were withdrawn from use and the contract with the original supplier was re-established. This incident resulted in contamination of samples only and no patient involvement. It highlights the problems which may follow use of equipment for unintended purposes and the need for good manufacturing practice guidelines to be applied to non-sterile equipment used in direct patient care.
authors.affiliation: Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: H
authors.initials: H
authors.lastname: Holzel
authors.forename: S
authors.initials: S
authors.lastname: Macqueen
authors.forename: A
authors.initials: A
authors.lastname: MacDonald
authors.forename: S
authors.initials: S
authors.lastname: Alexander
authors.forename: C K
authors.initials: CK
authors.lastname: Campbell
authors.forename: E M
authors.initials: EM
authors.lastname: Johnson
authors.forename: D W
authors.initials: DW
authors.lastname: Warnock
mesh_terms: D002648:Child; D002675:Child, Preschool; D004196:Disease Outbreaks; D004866:Equipment Contamination; D004865:Equipment and Supplies, Hospital / Q000382:microbiology; D006801:Humans; D007223:Infant; D017053:Infection Control / Q000379:methods; D008131:London; D009091:Mucormycosis / Q000453:epidemiology* / Q000209:etiology; D012233:Rhizopus / Q000302:isolation & purification*