title: Colorectal adenoma in patients with a history of breast cancer: a prospective study in Taiwan.
abstract: The increased incidence of colorectal cancer in women with a history of breast cancer is well established. However, the relationship between the prevalence of adenomatous polyps and breast cancer is still controversial. We conducted a prospective study of the incidence of colorectal polyps in patients with a history of breast cancer in Taiwan. Eighty-nine patients (86 women and 3 men) received colonoscopy to test for precancerous lesions. Mean age was 49.4 +/- 10.4 years. Twelve polyps (9 adenomatous, 2 hyperplastic, 1 inflammatory) (13.5%) and one cancer (1.1%) were found. The mean age of patients with and without colorectal neoplasia was 56.3 +/- 9.4 and 48.2 +/- 10.2 years respectively, (p < 0.005); 10 out of 13 patients (77%) with colorectal neoplasia were over 50 (p < 0.1). Compared with a study of Chinese people in Hong Kong, our population had a lower incidence of colorectal adenomatous polyps, but breast cancer patients have a greater risk of developing colorectal cancer than the general population in Taiwan.
authors.affiliation: Department of Gastroenterology, Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China.
authors.forename: C S
authors.initials: CS
authors.lastname: Wu
authors.forename: S Y
authors.initials: SY
authors.lastname: Tung
authors.forename: P C
authors.initials: PC
authors.lastname: Chen
authors.forename: Y C
authors.initials: YC
authors.lastname: Kuo
authors.forename: C Y
authors.initials: CY
authors.lastname: Wang
mesh_terms: D000236:Adenoma / Q000453:epidemiology*; D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000453:epidemiology*; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000453:epidemiology*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013624:Taiwan / Q000453:epidemiology