Orbital granulocytic sarcoma in an elderly patient.
OBJECTIVE
To report a 71-year-old woman with acute myelogenous leukemia in remission who developed orbital granulocytic sarcoma.


METHODS
The patient was referred for acute proptosis and decreased vision of the right eye. Computed tomography of the orbits demonstrated a right extraconal mass compressing the optic nerve. A right lateral orbitotomy was performed, and a portion of the mass was excised for diagnostic purposes and orbital decompression.


RESULTS
Histopathologic and immunohistochemical evaluation disclosed orbital granulocytic sarcoma. With chemotherapy and radiation, vision remained stable and right proptosis resolved.


CONCLUSIONS
Orbital granulocytic sarcoma is usually diagnosed in children with a history of acute myelogenous leukemia. This case demonstrated that this entity may also occur rarely in older patients with a history of acute myelogenous leukemia.
Watkins
L M
LM
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston 02114, USA.
Remulla
H D
HD
Rubin
P A
PA
D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005094:Exophthalmos / Q000473:pathology; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007951:Leukemia, Myeloid / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D008942:Mitoxantrone / Q000627:therapeutic use; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed; D014750:Vincristine / Q000627:therapeutic use; D014792:Visual Acuity
D014750:Vincristine; D008942:Mitoxantrone