Modulation of vincristine cytotoxicity by dexverapamil in sensitive and resistant HL-60 cell lines as a function of extracellular protein binding.
Stratmann
G
G
Institute for Clinical Pharmacology, University Hospital, Frankfurt am Main, Germany.
Harder
S
S
Hölzer
D
D
Hofmann
W K
WK
Ottmann
O G
OG
Woodcock
B G
BG
Hoffmann
W K
WK
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000037:antagonists & inhibitors*; D000972:Antineoplastic Agents, Phytogenic / Q000378:metabolism*; D001769:Blood; D002121:Calcium Channel Blockers / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D018432:Drug Resistance, Multiple; D005109:Extracellular Matrix / Q000378:metabolism; D018922:HL-60 Cells / Q000187:drug effects; D006801:Humans; D009961:Orosomucoid; D011485:Protein Binding / Q000187:drug effects; D014700:Verapamil / Q000494:pharmacology*; D014750:Vincristine / Q000378:metabolism*
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000972:Antineoplastic Agents, Phytogenic; D002121:Calcium Channel Blockers; D009961:Orosomucoid; D014750:Vincristine; D014700:Verapamil