[The diagnosis of hepatitis C viral infection in blood donors and patients].
The data on the examination of 5139 serum samples, obtained from 3358 blood donors and 1781 somatic patients, for the presence of HCV, HBV and HDV markers. Antibodies (Ab) to HCV were detected, on the average, in 1.56% of the examined blood donors (207 persons). Of these, in 1994 HCV markers were detected in 1.98% and HBV markers in 6.74% of cases, while in 1995 these markers were detected in 1.14% and 3.43% of cases respectively. The diagnosis of chronic viral hepatitis (mainly C) was verified in 14% of seropositive donors. In the group of somatic patients Ab to HCV were diagnosed in 130 examined patients (7.3%), in a half of the cases HCV and HBV coinfection being present. Similar percentage of coinfection was detected in blood donors. It should be pointed out that out of the total number of somatic patients only 4 patients had chronic viral hepatic diseases. Our data were compared with the data of medical statistics and were found to reflect the spread of HCV and HBV infection in the region among different groups of the population.
Ariamkina
O L
OL
State University, Central Medico-Sanitary Institution, Ulyanovsk, Russia.
Grigor'ev
Iu B
IuB
Fadeeva
G E
GE
Burganova
R A
RA
Maĭorova
G S
GS
Khalilova
R R
RR
Fatullaeva
E M
EM
Arslanova
R Kh
RKh
D000328:Adult; D015415:Biomarkers / Q000097:blood; D001782:Blood Donors / Q000706:statistics & numerical data; D005260:Female; D006509:Hepatitis B / Q000175:diagnosis / Q000453:epidemiology; D006526:Hepatitis C / Q000175:diagnosis* / Q000453:epidemiology; D018937:Hepatitis C Antibodies / Q000097:blood; D019698:Hepatitis C, Chronic / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D012426:Russia / Q000453:epidemiology; D016036:Seroepidemiologic Studies
D015415:Biomarkers; D018937:Hepatitis C Antibodies
O diagnostike infitsirovaniia virusom gepatita C donorov krovi i bol'nykh.