title: Antioxidative activities of several marine polysaccharides evaluated in a phosphatidylcholine-liposomal suspension and organic solvents.
abstract: The antioxidative activities of several water-soluble marine polysaccharides, alginate (ALG), alginate sulfate (SALG), propylene glucolalginate sodium sulfate (PSS), propylene glucol mannuronate sulfate (PGMS), the oligosaccharide of chitosan (OLC), N,O-carboxymethyl chitosan (NOCC) and hydroxypropylated chitosan (HPC), were examined in a phosphatidylcholine (PC)-liposomal suspension containing the water-soluble radical emitter, 2,2'-azobis (2-amidinopropane) dihydrochloride. In the suspensions containing OLC and SALG, the initial rates of PC-OOH accumulation were 2.78 x 10(-8) MS-1 and 2.88 x 10(-8) MS-1, respectively, while all the polysaccharides tested showed antioxidative activity. Liposoluble marine polysaccharides, hexanoyl chitin (HCH) and an N-benzoylhexanoyl chitosan (NBHC) solution, also retarded the hydroperoxide accumulation of methyl linoleate by effectively trapping peroxide radicals in organic solvents when the radical chain reaction had been initiated by 2,2'-azobis (2,4-dimethylvaleronitrile). The kinetic data presented indicate that the alginate and chitin derivatives can be expected to play a role in the antioxidative mechanism of biological systems.
authors.affiliation: Department of Food Science and Technology, Faculty of Fisheries, Ocean University of Qingdao, China.
authors.forename: C
authors.initials: C
authors.lastname: Xue
authors.forename: G
authors.initials: G
authors.lastname: Yu
authors.forename: T
authors.initials: T
authors.lastname: Hirata
authors.forename: J
authors.initials: J
authors.lastname: Terao
authors.forename: H
authors.initials: H
authors.lastname: Lin
mesh_terms: D000464:Alginates / Q000737:chemistry*; D000578:Amidines / Q000737:chemistry; D000975:Antioxidants / Q000737:chemistry*; D001391:Azo Compounds / Q000737:chemistry; D002084:Butylated Hydroxytoluene / Q000737:chemistry; D002686:Chitin / Q000031:analogs & derivatives* / Q000737:chemistry; D048271:Chitosan; D002851:Chromatography, High Pressure Liquid; D007700:Kinetics; D008041:Linoleic Acids / Q000737:chemistry; D008081:Liposomes; D009570:Nitriles / Q000737:chemistry; D016877:Oxidants / Q000737:chemistry; D010084:Oxidation-Reduction; D010713:Phosphatidylcholines / Q000378:metabolism*; D011134:Polysaccharides / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D014810:Vitamin E / Q000737:chemistry
chemical_list: D000464:Alginates; D000578:Amidines; D000975:Antioxidants; D001391:Azo Compounds; D008041:Linoleic Acids; D008081:Liposomes; D009570:Nitriles; D016877:Oxidants; D010713:Phosphatidylcholines; D011134:Polysaccharides; D012997:Solvents; C055792:2,2'-azobis(2,4-dimethylvaleronitrile); D002686:Chitin; D014810:Vitamin E; D002084:Butylated Hydroxytoluene; C005575:methyl linoleate; C046728:2,2'-azobis(2-amidinopropane); D048271:Chitosan