title: [A fulminant course of infection after splenectomy].
abstract: A report is given of two patients with a history of splenectomy many years previously due to traumatic rupture. No vaccination was given to either patient. From a state of good health, both patients developed fulminant, therapy-resistant sepsis with proof of Streptococcus pneumoniae in the blood culture. Autopsy findings were similar to Water-house-Friderichsen-syndrome. In conjunction with the history of splenectomy, the final pathological diagnosis was a so-called OPSI syndrome. This postsplenectomy sepsis is discussed further.
authors.affiliation: Institut für Pathologie, Hegau Klinikum, Singen.
authors.forename: M
authors.initials: M
authors.lastname: Rodríguez Gomez
authors.forename: U
authors.initials: U
authors.lastname: Oehler
authors.forename: B
authors.initials: B
authors.lastname: Helpap
mesh_terms: D000311:Adrenal Glands / Q000473:pathology; D000328:Adult; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male; D008875:Middle Aged; D014066:Palatine Tonsil / Q000473:pathology; D011008:Pneumococcal Infections / Q000473:pathology*; D011183:Postoperative Complications / Q000473:pathology*; D012772:Shock, Septic / Q000473:pathology*; D013154:Spleen / Q000473:pathology; D013156:Splenectomy; D013161:Splenic Rupture / Q000473:pathology / Q000601:surgery*; D014884:Waterhouse-Friderichsen Syndrome / Q000473:pathology
vernacular_title: Foudroyant verlaufende Sepsis nach Splenektomie.