[Significance of apoptotic processes in radiotherapy. I].
According to a considerable amount of publications apoptosis plays an important role for radio- and chemotherapy. The most important results related to this issue will be described in 2 independent articles, covering the following topics: Part I: I. definition, morphology, biochemical processes, II. clinical relevant detection assays, III. signal transduction. Part II: significance of apoptosis for radio- and chemotherapy.
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Akademie des Sanitäts- und Gesundheitswesens der Bundeswehr, Institut für Radiobiologie, München. 101653.1373@compuserve.com
van Beuningen
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D017209:Apoptosis / Q000528:radiation effects; D020170:Caspase 1; D002477:Cells / Q000378:metabolism / Q000473:pathology / Q000528:radiation effects; D003546:Cysteine Endopeptidases / Q000378:metabolism; D053938:DNA Fragmentation; D016521:Electrophoresis, Gel, Pulsed-Field; D005434:Flow Cytometry; D006801:Humans; D066298:In Vitro Techniques; D009336:Necrosis; D009369:Neoplasms / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology / Q000532:radiotherapy; D011493:Protein Kinase C / Q000378:metabolism; D011519:Proto-Oncogenes / Q000235:genetics; D011878:Radiotherapy; D017382:Reactive Oxygen Species / Q000378:metabolism; D015398:Signal Transduction / Q000528:radiation effects; D016159:Tumor Suppressor Protein p53 / Q000378:metabolism
D017382:Reactive Oxygen Species; D016159:Tumor Suppressor Protein p53; D011493:Protein Kinase C; D003546:Cysteine Endopeptidases; D020170:Caspase 1
Bedeutung apoptotischer Prozesse für die Strahlentherapie. Teil I.