title: Calculation of radiation exposures from patients to whom radioactive materials have been administered.
abstract: Spreadsheet templates which calculate cumulative exposures to other persons from patients to whom radioactive materials have been administered have been developed by the authors. Calculations can be based on any specified single-, bi- or tri-exponential whole-body clearance rate and a diurnal (or any other periodic) contact pattern. The time (post-administration) during which close contact should be avoided in order to constrain the radiation exposure and exposure rates to selected limits is also calculated using an iterative technique (Newton's method), and the residual activity at the time when contact can resume is also calculated. These templates find particular application in the calculation of exposures to persons who are in contact with patients who have received 131I for therapeutic purposes. The effect of changing dose limits, contact patterns and using individually derived clearance rates may be readily modelled.
authors.affiliation: Division of Medical Imaging, Flinders Medical Centre, Australia.
authors.forename: J
authors.initials: J
authors.lastname: Cormack
authors.forename: J
authors.initials: J
authors.lastname: Shearer
mesh_terms: D055592:Biophysical Phenomena; D001703:Biophysics; D003628:Database Management Systems; D006801:Humans; D007457:Iodine Radioisotopes / Q000009:adverse effects / Q000627:therapeutic use; D008657:Metabolic Clearance Rate; D008954:Models, Biological; D011829:Radiation Dosage; D019275:Radiopharmaceuticals / Q000009:adverse effects* / Q000627:therapeutic use; D011879:Radiotherapy Dosage; D013997:Time Factors
chemical_list: D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals