title: [Early infantile epileptic encephalopathy and glycine encephalopathy].
abstract: BACKGROUND
  Early infantile epileptic encephalopathy (EIEE) with suppression burst activity in EEG (Ohtahara syndrome) is a rare type of epileptic encephalopathy in infancy and represents the earliest type of age-related symptomatic generalized epilepsy. The main etiologic factors associated to EIEE are cerebral dysgenesia and metabolopathies, principally nonketotic hyperglycinemia.
  
  
  METHODS
  We report a neonate with EIEE secondary to glycine encephalopathy, diagnosed by increased of LCR/plasma glycine index.
authors.affiliation: Servicio de Pediatría, Hospital Universitario San Juan, Alicante, España.
authors.forename: J
authors.initials: J
authors.lastname: González de Dios
authors.forename: M
authors.initials: M
authors.lastname: Moya
authors.forename: C
authors.initials: C
authors.lastname: Pastore
authors.forename: V
authors.initials: V
authors.lastname: Izura
authors.forename: F
authors.initials: F
authors.lastname: Carratalà
mesh_terms: D001927:Brain Diseases / Q000209:etiology* / Q000503:physiopathology*; D004569:Electroencephalography; D004829:Epilepsy, Generalized / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology*; D017809:Fatal Outcome; D005260:Female; D005998:Glycine / Q000134:cerebrospinal fluid*; D006801:Humans; D007231:Infant, Newborn; D008661:Metabolism, Inborn Errors / Q000134:cerebrospinal fluid* / Q000150:complications*; D013577:Syndrome; D013997:Time Factors
chemical_list: D005998:Glycine
vernacular_title: Encefalopatía epiléptica infantil precoz y encefalopatía glicinémica.