Vascular pathogenesis of normal-tension glaucoma: a possible pathogenetic factor, other than intraocular pressure, of glaucomatous optic neuropathy.
Elevated intraocular pressure is significant in the pathogenesis of glaucomatous optic neuropathy in glaucoma, however a number of studies suggest that pressure-independent factor(s) are also associated with the pathogenesis. In this article, the significance of vascular pathogenesis in glaucoma is discussed. A brief overview of substances used to treat glaucoma, independent of an effect on intraocular pressure, such as calcium channel blockers, is also discussed.
Yamamoto
T
T
Department of Ophthalmology, Gifu University School of Medicine, Japan.
Kitazawa
Y
Y
D000818:Animals; D005902:Glaucoma, Open-Angle / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure; D009898:Optic Disk / Q000098:blood supply*; D009900:Optic Nerve / Q000098:blood supply*; D018917:Optic Neuropathy, Ischemic / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D014786:Vision Disorders / Q000209:etiology / Q000503:physiopathology; D014794:Visual Fields