title: [Transitory hyperinsulinism with hypoglycemia in asphyxia neonatorum].
abstract: BACKGROUND
  Hypoglycemia is a well-known complication in neonates small for gestational age and in those with diabetic mothers. Birth asphyxiated infants can develop severe hypoglycemia due to reduced glycogen stores.
  
  
  METHODS
  The first patient was born at 41 weeks, weighing 3,780 g by emergency cesarean section because of fetal distress. He developed a pneumothorax and hypoglycemia. He was given glucose infusion (at day 4: 20 mg/kg/d). Hyperinsulinism was confirmed: blood levels at 18.3 mU/L on day 1 and 11.7 mU/L on day 2. The infusion rate was gradually decreased. The second patient was born at 39 weeks, weighing 2,780 g by emergency cesarean section because of fetal distress. She needed glucose infusion (24 g/kg/d) because of hypoglycemia with hyperinsulinism (12.8 mU/L on day 2 and 11.7 mU/L on day 3). After 5 days, the infusion of glucose was replaced by oral feeding only.
  
  
  CONCLUSIONS
  Transient hypoglycemia in asphyxiated newborn infants with hyperinsulinism must be considered even when hypoglycemia may be difficult to prove.
authors.affiliation: Service de néonatologie, CHU Morvan, Brest, France.
authors.forename: J D
authors.initials: JD
authors.lastname: Giroux
authors.forename: E
authors.initials: E
authors.lastname: Vernotte
authors.forename: A
authors.initials: A
authors.lastname: Gagneur
authors.forename: C
authors.initials: C
authors.lastname: Metz
authors.forename: M
authors.initials: M
authors.lastname: Collet
authors.forename: L
authors.initials: L
authors.lastname: de Parscau
mesh_terms: D001238:Asphyxia Neonatorum / Q000150:complications*; D005260:Female; D006801:Humans; D006946:Hyperinsulinism / Q000150:complications* / Q000503:physiopathology; D007003:Hypoglycemia / Q000150:complications* / Q000503:physiopathology; D007231:Infant, Newborn; D008297:Male
vernacular_title: Hyperinsulinisme transitoire avec hypoglycémie par asphyxie néonatale.