title: Long-term results after repair of complete atrioventricular septal defects: analysis of risk factors.
abstract: BACKGROUND
  We analyzed data from 320 patients to evaluate the impact of different preoperative, operative, and postoperative factors on the outcome after repair of complete atrioventricular septal defect.
  
  
  METHODS
  Between October 1974 and December 1995, 320 patients with complete atrioventricular septal defect not associated with major cardiac anomalies were operated on. Two hundred seventy-four patients underwent total repair. Sixty-three patients (23%) were less than 6 months old. One hundred ninety-eight (72.2%) underwent primary repair. Seventy-six patients (27.7%) had a previous palliative operation.
  
  
  RESULTS
  Operative mortality in patients who underwent primary repair decreased from 17.6% (1974 to 1979) to 5.0% (1990 to 1995) despite an increase in the number of patients younger than 6 months. In patients undergoing a two-stage procedure operative mortality was 3.9% (late mortality, 7.9%). Young age (<6 months) was an incremental risk factor (p = 0.008) for operative mortality in the early study period. Coarctation of the aorta (p = 0.02) and severe dysplastic left atrioventricular valve (p = 0.001) were associated with a higher risk for operative mortality. Freedom from reoperation at 10 years was 82.5% +/- 3.8%.
  
  
  CONCLUSIONS
  In patients with complete atrioventricular septal defect, primary repair is the treatment of choice and can be accomplished with good results. In our experience over a period of more than 20 years, earlier date of operation, young age (<6 months), dysplastic left atrioventricular valve, and coexisting coarctation were incremental risk factors for hospital death. The presence of a previously placed pulmonary artery band did not alter the outcome of repair. The reconstructed atrioventricular valve shows a good and long-lasting performance.
authors.affiliation: Department of Cardiovascular Surgery, German Heart Center, Munich.
authors.forename: T
authors.initials: T
authors.lastname: Günther
authors.forename: D
authors.initials: D
authors.lastname: Mazzitelli
authors.forename: C J
authors.initials: CJ
authors.lastname: Haehnel
authors.forename: K
authors.initials: K
authors.lastname: Holper
authors.forename: F
authors.initials: F
authors.lastname: Sebening
authors.forename: H
authors.initials: H
authors.lastname: Meisner
mesh_terms: D000367:Age Factors; D001017:Aortic Coarctation / Q000150:complications; D006328:Cardiac Catheterization; D005500:Follow-Up Studies; D006343:Heart Septal Defects / Q000401:mortality / Q000601:surgery*; D006801:Humans; D007223:Infant; D008722:Methods; D011379:Prognosis; D012086:Reoperation; D012307:Risk Factors; D016896:Treatment Outcome