title: [Diagnosis of prostate cancer in urination disorders in urological practice: current status and future developments].
abstract: This paper presents the current diagnostics of patients with prostate related problems (lower urinary tract symptoms) who visit the urology clinic. The diagnostic triad for prostate cancer detection is presented, consisting of a serum Prostate-Specific Antigen test, a digital rectal examination to palpate the prostate, and transrectal ultrasound of the prostate to visualise internal structures and guide the urologist in taking biopsies. The results of the tests for a biopsied population of 232 patients illustrate the shortcomings of the individual tests in predicting the presence of a malignancy. Biopsies are needed to prove or rule out prostate cancer in case of a suspicion. Future developments in early detection of prostate cancer are directed to improve the clinical use of the current diagnostic triad, and to identify new diagnostic tools.
authors.affiliation: Afdeling Urologie Academisch Ziekenhuis Nijmegen.
authors.forename: R G
authors.initials: RG
authors.lastname: Aarnink
authors.forename: J J
authors.initials: JJ
authors.lastname: de la Rosette
authors.forename: J A
authors.initials: JA
authors.lastname: Witjes
authors.forename: F M
authors.initials: FM
authors.lastname: Debruyne
authors.forename: H
authors.initials: H
authors.lastname: Wijkstra
mesh_terms: D000368:Aged; D001707:Biopsy, Needle; D003663:Decision Trees; D005544:Forecasting; D006801:Humans; D008297:Male; D010173:Palpation; D010808:Physical Examination / Q000379:methods; D011237:Predictive Value of Tests; D011467:Prostate / Q000000981:diagnostic imaging / Q000473:pathology; D017430:Prostate-Specific Antigen / Q000302:isolation & purification; D011471:Prostatic Neoplasms / Q000150:complications / Q000175:diagnosis*; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D014555:Urination Disorders / Q000175:diagnosis / Q000209:etiology*; D014572:Urology / Q000639:trends
chemical_list: D017430:Prostate-Specific Antigen
vernacular_title: Diagnostiek van prostaatkanker bij mictieklachten in de urologische praktijk: huidige stand van zaken en toekomstige ontwikkelingen.