[Mesenteric lipoblastoma with changes in chromosome 8: use of cytogenetics in the diagnosis of adipocytic tumors in children].
Lipoblastoma is a rare type of benign tumor occurring in infants. We report a case of mesenteric lipoblastoma with histologic, electron microscopic and cytogenetic studies. The microscopic features of this tumor including lipoblastic proliferation and prominent immature capillary beds were typical of lipoblastoma. Cytogenetic study showed a karyotype 46,XX, inv (8) (p 21.1; q 24.2). We discuss the usefulness of cytogenetic study associated to fluorescent in situ hybridization, in the diagnosis of the lipoblastic tumors, i.e. myoxoid liposarcoma and lipoblastoma.
François
A
A
Laboratoire d'Anatomie Pathologique, Hôpital Charles Nicolle, CHU de Rouen.
Bodenant
C
C
Rives
N
N
Bachy
B
B
Mitrofanoff
P
P
Mace
B
B
Hemet
J
J
D002869:Chromosome Aberrations / Q000175:diagnosis*; D025063:Chromosome Disorders; D002898:Chromosomes, Human, Pair 8; D005260:Female; D006801:Humans; D007223:Infant; D007621:Karyotyping; D008067:Lipoma / Q000175:diagnosis* / Q000235:genetics; D008643:Mesentery; D010534:Peritoneal Neoplasms / Q000175:diagnosis* / Q000235:genetics
Lipoblastome mésentérique avec remaniement du chromosome 8: apport de la cytogénétique dans le diagnostic des tumeurs adipocytaires de l'enfant.