Fatty acids bind directly to and activate peroxisome proliferator-activated receptors alpha and gamma.
Peroxisome proliferator-activated receptors alpha and gamma function in lipid homeostasis. The receptors are activated by direct binding of hypolipidemic drugs and of mono- and polyunsaturated fatty acids. Upon activation, these receptors interact with a number of different genes involved in lipid metabolism.
Wolf
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Department of Nutritional Sciences, University of California, Berkeley 94720-3104, USA.
D000818:Animals; D004247:DNA / Q000378:metabolism; D005227:Fatty Acids / Q000378:metabolism*; D006706:Homeostasis / Q000235:genetics; D006801:Humans; D050356:Lipid Metabolism; D018160:Receptors, Cytoplasmic and Nuclear / Q000235:genetics / Q000378:metabolism*; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*; D014162:Transfection
D005227:Fatty Acids; D018160:Receptors, Cytoplasmic and Nuclear; D014157:Transcription Factors; D004247:DNA