Tissue-specific distribution of mouse casein kinase I alpha mRNA.
A clone isolated from a mouse skeletal muscle cDNA library by differentially screening for sequences expressed in skeletal but not cardiac muscle was found to correspond to the a-isoform of casein kinase I. The bulk of the clone corresponded to the 3'-untranslated region of the mRNA, which is isoform-specific. Hybridization to mRNA indicated a tissue-specific distribution for this isoform of casein kinase I.
McInnes
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Department of Biochemistry, University of Glasgow, U.K.
Leader
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DP
D000818:Animals; D001483:Base Sequence; D001921:Brain / Q000378:metabolism; D047388:Casein Kinases; D018076:DNA, Complementary; D008099:Liver / Q000378:metabolism; D051379:Mice; D008969:Molecular Sequence Data; D018482:Muscle, Skeletal / Q000378:metabolism; D009206:Myocardium / Q000378:metabolism; D009928:Organ Specificity; D014176:Protein Biosynthesis; D011494:Protein Kinases / Q000235:genetics* / Q000378:metabolism*; D017422:Sequence Analysis, DNA; D014018:Tissue Distribution
D018076:DNA, Complementary; D011494:Protein Kinases; D047388:Casein Kinases