title: Clinical versus statistical considerations in the design and analysis of clinical research.
authors.affiliation: Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: R I
authors.initials: RI
authors.lastname: Horwitz
authors.forename: B H
authors.initials: BH
authors.lastname: Singer
authors.forename: R W
authors.initials: RW
authors.lastname: Makuch
authors.forename: C M
authors.initials: CM
authors.lastname: Viscoli
mesh_terms: D002986:Clinical Trials as Topic / Q000379:methods / Q000706:statistics & numerical data*; D003627:Data Interpretation, Statistical; D006801:Humans; D012107:Research Design