title: Juvenile xanthogranuloma of the iris in an adult.
abstract: Juvenile xanthogranuloma is a self-limited skin disorder of young children that uncommonly affects the eye. Juvenile xanthogranuloma has been described in adults, but reported intraocular involvement is extremely rare. We report a case of juvenile xanthogranuloma diagnosed in a 25-year-old man who was seen with nontraumatic hyphema and iridocyclitis. Diagnosis was made from a biopsy specimen obtained from a suspicious skin lesion. Topical and systemic steroids, radiation therapy, and finally immunosupression were required to eliminate the iris tumor clinically and resolve the patient's recurrent symptoms.
authors.affiliation: Department of Surgery, Madigan Army Medical Center, Tacoma, Wash, USA. Goteborg@AOL.com
authors.forename: V C
authors.initials: VC
authors.lastname: Parmley
authors.forename: D P
authors.initials: DP
authors.lastname: George
authors.forename: L A
authors.initials: LA
authors.lastname: Fannin
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D006801:Humans; D006988:Hyphema / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D015863:Iridocyclitis / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D007499:Iris Diseases / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy; D008297:Male; D008727:Methotrexate / Q000627:therapeutic use; D014972:Xanthogranuloma, Juvenile / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy
chemical_list: D007166:Immunosuppressive Agents; D008727:Methotrexate