[Recovery of normal stressor reactions in rats with disrupted brain limbic structures by delta-sleep inducing peptide].
Administration of the DSIP improved resistance against stress in rats with septal or amygdalar brain lesions, the latter structures playing an important part in the resistance mechanisms. Bilateral lesion of these structures significantly decreased the resistance against emotional stress in rats.
Koplik
E V
EV
P. K. Anokhin Institute of Normal Physiology, Russian Acad. Med. Sci., Moscow, Russia.
Sudakov
K V
KV
D000311:Adrenal Glands / Q000187:drug effects / Q000473:pathology; D000679:Amygdala / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology; D000818:Animals; D003701:Delta Sleep-Inducing Peptide / Q000378:metabolism / Q000494:pharmacology*; D004558:Electric Stimulation; D008032:Limbic System / Q000187:drug effects* / Q000473:pathology / Q000503:physiopathology; D008297:Male; D009043:Motor Activity / Q000187:drug effects; D009929:Organ Size; D051381:Rats; D017208:Rats, Wistar; D012149:Restraint, Physical; D012686:Septal Nuclei / Q000187:drug effects / Q000473:pathology / Q000503:physiopathology; D013315:Stress, Psychological / Q000503:physiopathology*; D013950:Thymus Gland / Q000187:drug effects / Q000473:pathology
D003701:Delta Sleep-Inducing Peptide
Vosstanovlenie émotsional'nykh stressornykh reaktsiĭ u krys s razrushennymi limbicheskimi strukturami mozga peptidom, vyzyvaiushchim del'ta-son.