title: A novel technology for packing and unpacking pilot and production scale columns.
abstract: A new method of packing and unpacking large scale chromatography columns is described. This involves use of a 3-position valve that can inject chromatography media into a closed column thereby packing it. This same valve in another state is then used to unpack the column. Heights equivalent to a theoretical plate and asymmetry factors of packs on columns from 280 to 800 mm diameter are discussed.
authors.affiliation: Euroflow (UK) Ltd., Unit 4, Stroud, Gloucestershire, UK.
authors.forename: M
authors.initials: M
authors.lastname: Hofmann
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods*; D012685:Sepharose
chemical_list: D012685:Sepharose