title: The effect of drug lipophilicity on P-glycoprotein-mediated colchicine efflux at the blood-brain barrier.
authors.affiliation: King's College, London, UK.
authors.forename: E U
authors.initials: EU
authors.lastname: Khan
authors.forename: A
authors.initials: A
authors.lastname: Reichel
authors.forename: D J
authors.initials: DJ
authors.lastname: Begley
authors.forename: S J
authors.initials: SJ
authors.lastname: Roffey
authors.forename: S G
authors.initials: SG
authors.lastname: Jezequel
authors.forename: N J
authors.initials: NJ
authors.lastname: Abbott
mesh_terms: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000037:antagonists & inhibitors*; D000818:Animals; D001812:Blood-Brain Barrier / Q000187:drug effects*; D002460:Cell Line; D003078:Colchicine / Q000378:metabolism*; D016572:Cyclosporine / Q000737:chemistry / Q000494:pharmacology; D004176:Dipyridamole / Q000737:chemistry / Q000494:pharmacology; D008055:Lipids / Q000737:chemistry*; D051381:Rats; D012995:Solubility; D014700:Verapamil / Q000737:chemistry / Q000494:pharmacology; D015215:Zidovudine / Q000737:chemistry / Q000494:pharmacology
chemical_list: D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D008055:Lipids; D015215:Zidovudine; D004176:Dipyridamole; D016572:Cyclosporine; D014700:Verapamil; D003078:Colchicine