An erythema multiforme-like eruption caused by exposure to 1-chloromethylnaphthalene.
A young male patient developed an erythema multiforme-like eruption following an accidental exposure to 1-chloromethylnaphthalene (1-CMN). In addition to the skin lesion, he suffered from liver involvement and tear insufficiency. Positive results of a patch test with 1-CMN and an in vitro lymphocyte transformation test suggested that direct exposure of the skin to chemical compounds was the probable cause of his symptoms.
Urano
S
S
Department of Dermatology, Ensyu General Hospital, Hamamatsu, Japan.
Tokura
Y
Y
D000287:Administration, Topical; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002617:Chemical Industry; D056486:Chemical and Drug Induced Liver Injury; D004892:Erythema Multiforme / Q000139:chemically induced* / Q000188:drug therapy; D005938:Glucocorticoids; D006801:Humans; D008213:Lymphocyte Activation / Q000187:drug effects; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009281:Naphthalenes / Q000009:adverse effects*; D009784:Occupational Diseases / Q000139:chemically induced* / Q000188:drug therapy; D010328:Patch Tests; D013666:Tears / Q000187:drug effects; D014985:Xerophthalmia / Q000139:chemically induced
C111381:1-chloromethylnaphthalene; D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D009281:Naphthalenes; C031721:naphthalene; D008775:Methylprednisolone