Leptin in human plasma is derived in part from the brain, and cleared by the kidneys.
Esler
M
M
Vaz
M
M
Collier
G
G
Nestel
P
P
Jennings
G
G
Kaye
D
D
Seals
D
D
Lambert
G
G
D000328:Adult; D000368:Aged; D001921:Brain / Q000378:metabolism*; D006801:Humans; D007668:Kidney / Q000378:metabolism*; D020738:Leptin; D008297:Male; D008657:Metabolic Clearance Rate; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism*; D011506:Proteins / Q000378:metabolism*
D020738:Leptin; D011506:Proteins