Bioactivation of 2-amino-3-methylimidazo[4,5-f] quinoline (IQ) by prostaglandin H synthase.
Degen
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GH
Institut für Arbeitsphysiologie an der Universität Dortmund (IfADo), Germany.
Wolz
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Gerber
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Pfau
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D000818:Animals; D001711:Biotransformation; D018929:Cell Culture Techniques; D018736:DNA Adducts / Q000032:analysis; D008297:Male; D015162:Micronucleus Tests; D009152:Mutagenicity Tests; D009153:Mutagens / Q000493:pharmacokinetics* / Q000633:toxicity; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism*; D011804:Quinolines / Q000493:pharmacokinetics* / Q000633:toxicity; D012486:Salmonella typhimurium / Q000187:drug effects / Q000378:metabolism; D012669:Seminal Vesicles / Q000187:drug effects / Q000648:ultrastructure; D012756:Sheep
D018736:DNA Adducts; D009153:Mutagens; D011804:Quinolines; C029216:2-amino-3-methylimidazo(4,5-f)quinoline; D011451:Prostaglandin-Endoperoxide Synthases