title: Correlation between the M and F wave characteristics and the innervated muscle strength in spinal muscular atrophy.
abstract: The purpose of this study is to elucidate the interrelation between the M and F wave characteristics of the median nerve and the grip power in patients with spinal muscular atrophy (SMA). The SMA patients showed decreased amplitudes of the M and F waves, decreased frequency of the F wave, and an increase of the F/M ratio as compared with the normative values. The F wave frequency and the amplitudes of M and F waves, which showed a significant linear correlation with each other, became lower in accordance with the decrease of grip power. The properties of M and F waves strongly correlated with the number of surviving motor neurons which would be fewer in those severely affected by SMA.
authors.affiliation: Department of Neurology, School of Medicine, Sapporo Medical University, Japan. toimai@sapmed.ac.jp
authors.forename: T
authors.initials: T
authors.lastname: Imai
authors.forename: M
authors.initials: M
authors.lastname: Saito
authors.forename: H
authors.initials: H
authors.lastname: Matsumoto
authors.forename: Y
authors.initials: Y
authors.lastname: Ishikawa
authors.forename: Y
authors.initials: Y
authors.lastname: Ishikawa
authors.forename: R
authors.initials: R
authors.lastname: Minami
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D004558:Electric Stimulation; D004576:Electromyography; D005260:Female; D006225:Hand; D018737:Hand Strength; D006801:Humans; D008297:Male; D008475:Median Nerve / Q000503:physiopathology*; D018482:Muscle, Skeletal / Q000294:innervation* / Q000503:physiopathology*; D009134:Muscular Atrophy, Spinal / Q000503:physiopathology*; D009431:Neural Conduction / Q000502:physiology; D012016:Reference Values; D013997:Time Factors