title: Exactness of source analysis of biomagnetic signals of epileptiform spikes by the method of spatial filtering: a computer simulation.
abstract: On the basis of spatial covariance it is found that, by spatial filtering the localisation of a single dipole source, both parallel and perpendicular to the measurement plane (assuming a signal-noise ratio of 5:1), can be performed with an accuracy of < 0.5 mm. When the signal-noise ratio is increased to 30:1, the resolution of temporally independent current sources separated by 2 mm becomes practicable. This resolution study is carried out by means of a pair of unity current dipoles with the dipole distance as a varying source model parameter. The conclusions, drawn from the results of computer simulation and supported by statistical calculations, refer to the spherical model of the volume conductor of the brain.
authors.affiliation: Institute of Pathological Physiology, Klinikum Friedrich Schiller Universität, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Wagner
authors.forename: M
authors.initials: M
authors.lastname: Eiselt
authors.forename: U
authors.initials: U
authors.lastname: Zwiener
mesh_terms: D003198:Computer Simulation; D004828:Epilepsies, Partial / Q000503:physiopathology*; D006801:Humans; D015225:Magnetoencephalography / Q000379:methods*; D008433:Mathematics; D008959:Models, Neurological; D012815:Signal Processing, Computer-Assisted