Hyperbaric oxygen therapy in a case of post-total body irradiation colitis.
We report a 21-year-old man who experienced symptoms of colitis following autologous TBI-conditioned PBSC transplantation, which persisted despite conventional treatment. Abdominal echography showed a thickened, stratified wall of the cecum, of the right colon and of part of the transverse colon. Hyperbaric oxygen therapy (20 sessions of 100% oxygen inhalation at 2.5 bar for 120 min in a hyperbaric chamber) achieved a prompt clinical recovery as well as complete disappearance of the ultrasound abnormalities.
Favre
C
C
Bone Marrow Transplant Unit, Institute of Pediatrics, University of Pisa, Italy.
Ventura
A
A
Nardi
M
M
Massimetti
M
M
Papineschi
F
F
Macchia
P
P
D000005:Abdomen / Q000000981:diagnostic imaging; D000328:Adult; D003092:Colitis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D006931:Hyperbaric Oxygenation; D008228:Lymphoma, Non-Hodgkin / Q000150:complications / Q000532:radiotherapy; D008297:Male; D012008:Recurrence; D019172:Transplantation Conditioning; D014463:Ultrasonography; D014916:Whole-Body Irradiation / Q000009:adverse effects*