Vasodilator component in sympathetic nerve activity destined for the skin of the dorsal foot of mildly heated humans.
1. Skin sympathetic nerve activity (SSNA) was recorded in seven male subjects from the peroneal nerve by microneurography, and the temporal correspondence of spontaneously occurring SSNA bursts with vasodilatation and sweating responses on the dorsal foot was studied during a mild body heating at rest. 2. Some SSNA bursts were followed by a sweat expulsion with a latency of 2.4 +/- 0.4 s, and some bursts by a transient vasodilatation with a latency of 2.2 +/- 0.4 s (means +/- S.D.). SSNA bursts followed both by a sweat expulsion and by a vasodilatation response (Type 1), those followed only by a sweat expulsion (Type 2) and those followed only by a vasodilatation, response (Type 3) were 70%, 10% and 1% of the total bursts examined, respectively. 3. For Type 1 bursts, there was a significant, but weak linear relationship among the burst amplitude, the amplitude of the corresponding vasodilatation and the amplitude of the corresponding sweat expulsion. 4. It was concluded that SSNA contains vasodilatory activity which is synchronous with sudomotor nerve activity. The results suggest that such vasodilatory activity contributes to sustaining the sweat gland function by supplying sufficient blood.
Sugenoya
J
J
Department of Physiology, Aichi Medical University, Japan. sugenoya@aichi-med-u.ac.jp
Iwase
S
S
Mano
T
T
Sugiyama
Y
Y
Ogawa
T
T
Nishiyama
T
T
Nishimura
N
N
Kimura
T
T
D000328:Adult; D005528:Foot / Q000098:blood supply / Q000294:innervation* / Q000502:physiology*; D006358:Hot Temperature; D006801:Humans; D008297:Male; D008839:Microelectrodes; D009451:Neuroeffector Junction / Q000502:physiology; D012039:Regional Blood Flow / Q000502:physiology; D012867:Skin / Q000098:blood supply / Q000294:innervation*; D013546:Sweating / Q000502:physiology; D013564:Sympathetic Nervous System / Q000502:physiology*; D014664:Vasodilation / Q000502:physiology*