Experiences of the 14C-ethanol technique for blood flow measurements in human subcutaneous adipose tissue.
We compared the 14C-ethanol technique and 133Xe-clearance for adipose tissue blood flow measurements in young healthy subjects before and after exercise on an ergometer bicycle. The results showed a decrease in outflow/inflow ratio of 14C-ethanol during the basal situation before the exercise, indicating an increased blood flow. However, there was a great range of values, and no correlation between the 14C-ethanol technique and 133Xe-clearance was found. Our data indicate that the 14C-ethanol technique can not be recommended in its current form.
Børsheim
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The Norwegian University of Sport and Physical Education, Department of Physiology, National Institute of Occupational Health, Oslo. elisab@idrettshs.brage.no
Jansson
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PA
D000273:Adipose Tissue / Q000098:blood supply* / Q000378:metabolism; D000328:Adult; D002250:Carbon Radioisotopes / Q000493:pharmacokinetics; D000431:Ethanol / Q000493:pharmacokinetics*; D015444:Exercise; D006801:Humans; D012016:Reference Values; D012039:Regional Blood Flow; D014980:Xenon Radioisotopes / Q000493:pharmacokinetics
D002250:Carbon Radioisotopes; D014980:Xenon Radioisotopes; D000431:Ethanol