Antimicrobial peptides of vertebrates.
The past year brought several discoveries that focused attention on antimicrobial peptides on epithelial surfaces. The malfunction of these substances was implicated as a cause of airway infections in cystic fibrosis. Other highlights included new insights into the relative selectivity of antimicrobial peptides for microbial membranes, their primary site of action.
Ganz
T
T
Department of Medicine, University of California School of Medicine, Los Angeles 90095-1690, USA. tganz@ucla.edu
Lehrer
R I
RI
D000818:Animals; D000890:Anti-Infective Agents / Q000276:immunology*; D023181:Antimicrobial Cationic Peptides / Q000276:immunology*; D001798:Blood Proteins / Q000276:immunology; D054804:Cathelicidins; D023082:Defensins; D006801:Humans; D007448:Invertebrates / Q000276:immunology*; D014714:Vertebrates / Q000276:immunology
D000890:Anti-Infective Agents; D023181:Antimicrobial Cationic Peptides; D001798:Blood Proteins; D054804:Cathelicidins; D023082:Defensins