Recombinant allergens for immunotherapy: a Der p 2 variant with reduced IgE reactivity retains T-cell epitopes.
Smith
A M
AM
Asthma and Allergic Diseases Center, Department of Medicine, University of Virginia, Charlottesville 22908, USA.
Chapman
M D
MD
Taketomi
E A
EA
Platts-Mills
T A
TA
Sung
S S
SS
D039741:Antigens, Dermatophagoides; D002455:Cell Division; D000939:Epitopes / Q000235:genetics / Q000276:immunology; D006023:Glycoproteins / Q000235:genetics* / Q000276:immunology*; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology*; D007167:Immunotherapy / Q000379:methods; D007963:Leukocytes, Mononuclear / Q000276:immunology; D016297:Mutagenesis, Site-Directed; D011994:Recombinant Proteins / Q000276:immunology*; D012882:Skin Tests; D013601:T-Lymphocytes / Q000166:cytology / Q000276:immunology*
D039741:Antigens, Dermatophagoides; D000939:Epitopes; D006023:Glycoproteins; D011994:Recombinant Proteins; D007073:Immunoglobulin E