Methotrexate induced pericarditis and pericardial effusion in psoriatic patient.
We describe a 62-year-old woman with Psoriasis who presented as Methotrexate-induced pericarditis and pericardial effusion. Aspiration of the pericardium was required and the patient made a satisfactory recovery. At six-months follow-up, she remained well, psoriasis plaques was controlled by topical crude coal tar and topical corticosteroid. These complications are extremely rare, but have been described as isolated phenomena associated with methotrexate therapy.
Palungwachira
P
P
Family Medicine Department, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Palungwachira
P
P
Laohathai
P
P
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000009:adverse effects*; D004452:Echocardiography; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D010490:Pericardial Effusion / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D010493:Pericarditis / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D011565:Psoriasis / Q000188:drug therapy; D013396:Suction
D000305:Adrenal Cortex Hormones; D003879:Dermatologic Agents; D008727:Methotrexate