title: Comparison of carbon dioxide and air pneumoperitoneum for gamete intrafallopian transfer under conscious sedation and local anesthesia.
abstract: OBJECTIVE
  To compare patient tolerance and pregnancy rates (PRs) between two cohorts that underwent GIFT under local anesthesia with air versus carbon dioxide (CO2) pneumoperitoneum.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  University clinic.
  
  
  METHODS
  Eighty-five patients who underwent 125 laparoscopies under conscious sedation for GIFT using air pneumoperitoneum were compared with 42 patients who had 70 GIFT procedures with CO2 pneumoperitoneum.
  
  
  METHODS
  Transvaginal ultrasound-guided egg retrieval followed by GIFT with compressed air or CO2 for pneumoperitoneum under local anesthesia and i.v. sedation.
  
  
  METHODS
  Patient tolerance and viable PR.
  
  
  RESULTS
  The percentage of patients scoring "very good" was lower in the CO2 group (73% for air versus 57% for CO2), but the combined percentage of those scoring "very good" or "good" was comparable at 89% and 87%. The difference in the viable PRs between the two groups (43% versus 37%) for patients < 40 years old was not statistically significant.
  
  
  CONCLUSIONS
  Patient tolerance and PRs are similar for air and CO2 pneumoperitoneum during GIFT under local anesthesia. Given the theoretical risk of air embolus and lack of detrimental effect of CO2 on patient tolerance and success rate, it seems prudent to use CO2 in such a setting.
authors.affiliation: Department of Gynecology and Obstetrics, Stanford University School of Medicine, California 94305, USA.
authors.forename: A A
authors.initials: AA
authors.lastname: Milki
authors.forename: S I
authors.initials: SI
authors.lastname: Tazuke
mesh_terms: D000328:Adult; D000388:Air; D000772:Anesthesia, Local; D002245:Carbon Dioxide; D016292:Procedural Sedation; D005260:Female; D015181:Gamete Intrafallopian Transfer / Q000379:methods*; D006801:Humans; D011028:Pneumoperitoneum, Artificial; D011247:Pregnancy
chemical_list: D002245:Carbon Dioxide