title: [Anticoagulant rodenticide poisoning in dogs in The Netherlands].
abstract: The occurrence, the diagnosis, and the treatment of anticoagulant rodenticide poisoning in dogs in the Netherlands was evaluated by a survey among Dutch veterinarians carried out by the National Poisons Control Center (NPCC). The survey included information on 54 dogs, 32 being treated by veterinarians who consulted the NPCC and 22 that were admitted to the Utrecht University Clinic for Companion Animals (UUCCA). The poisons that were suspected were brodifacoum (n = 19), bromadiolone (n = 14), difenacoum (n = 8), difethialone (n = 6) and chlorophacinone (n = 1). In 6 dogs the identity of the poison was unknown. Of 31 dogs with hemorrhages, 2 died shortly after presentation to practitioners and 2 died shortly after admission to the UUCCA. Signs of bleeding occurred especially in poisoning by brodifacoum (n = 16). In all but one of the dogs without hemorrhages, the intake of poison had taken place within 24 hours before presentation. The method of treatment varied, with the induction of vomiting and the use of vitamin K mentioned most. The choice of therapy was determined by the length of time after intake of the poison, the clinical signs and whether or not an anticoagulant toxicosis was suspected at the time of the initial examination. These findings provide the basis for discussion of several aspects of diagnosis and treatment.
authors.affiliation: Intensieve Zorg Afdeling, Faculteit der Diergeneeskunde, Universiteit Utrecht.
authors.forename: J H
authors.initials: JH
authors.lastname: Robben
authors.forename: H C
authors.initials: HC
authors.lastname: Mout
authors.forename: E A
authors.initials: EA
authors.lastname: Kuijpers
mesh_terms: D000818:Animals; D000925:Anticoagulants / Q000494:pharmacology / Q000506:poisoning*; D001774:Blood Chemical Analysis / Q000662:veterinary; D004283:Dog Diseases / Q000139:chemically induced*; D004285:Dogs; D011041:Poisoning / Q000097:blood / Q000662:veterinary; D012378:Rodenticides / Q000494:pharmacology / Q000506:poisoning*
chemical_list: D000925:Anticoagulants; D012378:Rodenticides
vernacular_title: Rodenticide anticoagulans-intoxicatie bij honden in Nederland.