title: Improved disease resistance after Babesia divergens vaccination.
abstract: The efficacy of a new inactivated vaccine against Babesia divergens was evaluated by means of inoculation tests. The infection was initiated by i.v. injection of blood containing 2 x 10(9) living parasites into splenectomized and non-splenectomized calves. Clinical status and hematological parameters were determined. Serology examinations for antibodies against B. divergens were carried out by indirect fluorescent antibody test (IFAT). Non-vaccinated and splenectomized animals exhibited experimental infections. In vaccinated and splenectomized animals, clinical symptoms and prolonged incubation periods were observed.
authors.affiliation: Department of Parasitology and Zoology, Veterinary Medical University, Vienna, Austria.
authors.forename: R
authors.initials: R
authors.lastname: Edelhofer
authors.forename: A
authors.initials: A
authors.lastname: Kanout
authors.forename: M
authors.initials: M
authors.lastname: Schuh
authors.forename: E
authors.initials: E
authors.lastname: Kutzer
mesh_terms: D000818:Animals; D001403:Babesia / Q000276:immunology* / Q000302:isolation & purification; D001404:Babesiosis / Q000097:blood / Q000276:immunology / Q000469:parasitology / Q000517:prevention & control*; D002417:Cattle; D002418:Cattle Diseases / Q000097:blood / Q000276:immunology / Q000469:parasitology / Q000517:prevention & control*; D019084:Fluorescent Antibody Technique, Indirect / Q000662:veterinary; D007113:Immunity, Innate / Q000276:immunology; D007074:Immunoglobulin G / Q000097:blood / Q000302:isolation & purification; D008297:Male; D018512:Parasitemia / Q000175:diagnosis / Q000662:veterinary; D016052:Protozoan Vaccines / Q000008:administration & dosage* / Q000276:immunology; D013156:Splenectomy / Q000662:veterinary; D015164:Vaccines, Inactivated / Q000008:administration & dosage / Q000276:immunology
chemical_list: D007074:Immunoglobulin G; D016052:Protozoan Vaccines; D015164:Vaccines, Inactivated