title: Effectiveness and limits of preoperative imaging studies for the localisation of pheochromocytomas and paragangliomas: a review of 282 cases. French Association of Surgery (AFC), and The French Association of Endocrine Surgeons (AFCE).
abstract: OBJECTIVE
  To find out the optimal strategy for the preoperative location of pheochromocytomas and paragangliomas.
  
  
  METHODS
  Retrospective study.
  
  
  METHODS
  282 patients operated on for histologically confirmed pheochromocytoma in France between 1980 and 1991, the past decade.
  
  
  METHODS
  The results of imaging procedures, i.e. computed tomography (CT), (131)I meta-iodobenzylguanidine scintigraphy (MIBG) and magnetic resonance imaging (MRI) were reviewed.
  
  
  RESULTS
  Pheochromocytomas were sporadic in 206 (73%). They were unilateral in 189 (67%), bilateral in 54 (19%) and extra-adrenal in 39 (14%). Overall sensitivity of the studies was 89% for CT, 98% for MRI, and 81% for (131)I-MIBG. In unilateral adrenal lesions sensitivity were 100% for CT and MRI, and 88% for (131)I-MIBG; in bilateral lesions 66% for CT, 100% for MRI, and 62% for (131)I-MIBG; in extra-adrenal lesions 64% for CT, 88% for MRI, and 64% for (131)I-MIBG.
  
  
  CONCLUSIONS
  The accuracy with which pheochromocytomas and paragangliomas can be visualized questions nowadays the routine use of abdominal approach. In selected cases of sporadic unilateral chromaffin tumours, a posterior, lateral, or even laparoscopic approach should be considered.
authors.affiliation: Clinique Chirurgicale, Hopital Huriez, Lille, France.
authors.forename: N D
authors.initials: ND
authors.lastname: Jalil
authors.forename: F N
authors.initials: FN
authors.lastname: Pattou
authors.forename: F
authors.initials: F
authors.lastname: Combemale
authors.forename: Y
authors.initials: Y
authors.lastname: Chapuis
authors.forename: J F
authors.initials: JF
authors.lastname: Henry
authors.forename: J L
authors.initials: JL
authors.lastname: Peix
authors.forename: C A
authors.initials: CA
authors.lastname: Proye
mesh_terms: D000008:Abdominal Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010235:Paraganglioma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D010386:Pelvic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D010673:Pheochromocytoma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000601:surgery; D011300:Preoperative Care; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed