Plasmablastic lymphoma of the stomach. A case report.
We report the case of a 53 year-old woman with a gastric tumor showing morphological, phenotypical and molecular features of a plasmablastic lymphoma, a recently recognized subtype of diffuse large B-cell lymphoma. The tumor was composed of plasmablast-like cells, lacked CD45 and B-cell associated antigens, expressed the plasma cell-associated antigen CD38, and showed clonally rearranged IgH genes in the absence of bcl-2 and bcl-6 genes rearrangement.
Pruneri
G
G
II Servizio di Anatomia Patologica, Istituto di Scienze Mediche, IRCCS Ospedale Maggiore di Milan, Italy.
Graziadei
G
G
Ermellino
L
L
Baldini
L
L
Neri
A
A
Buffa
R
R
D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000473:pathology; D016403:Lymphoma, Large B-Cell, Diffuse / Q000473:pathology*; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000473:pathology*