Simultaneous determination of chlorzoxazone, indicator of CYP2E1, and its metabolite in human serum using a new reversed-phase chromatographic column of 2-microm porous microspherical silica-gel.
Tanaka
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Department of Legal Medicine, Institute of Community Medicine, University of Tsukuba, Ibaraki-ken, Japan. einosuke@md.tsukuba.ac.jp
D002753:Chlorzoxazone / Q000031:analogs & derivatives* / Q000097:blood; D002851:Chromatography, High Pressure Liquid / Q000295:instrumentation*; D019392:Cytochrome P-450 CYP2E1 / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010316:Particle Size; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D058428:Silica Gel; D012822:Silicon Dioxide
C039289:6-hydroxychlorzoxazone; D058428:Silica Gel; D012822:Silicon Dioxide; D019392:Cytochrome P-450 CYP2E1; D002753:Chlorzoxazone