title: Frequent gene conversion between human red and green opsin genes.
abstract: To study the evolution of human X-linked red and green opsin genes, genomic sequences in large regions of the two genes were compared. The divergences in introns 3, 4, and 5 and the 3' flanking sequence of the two genes are significantly lower than those in exons 4 and 5. The homogenization mechanism of introns and the 3' flanking sequence of human red and green opsin genes is probably gene conversion, which also occurred in exons 1 and 6. At least one gene conversion event occurred in each of three regions (1, 3, and 5) in the sequences compared. In conclusion, gene conversion has occurred frequently between human red and green opsin genes, but exons 2, 3, 4, and 5 have been maintained distinct between the two genes by natural selection.
authors.forename: Z
authors.initials: Z
authors.lastname: Zhao
authors.forename: D
authors.initials: D
authors.lastname: Hewett-Emmett
authors.forename: W H
authors.initials: WH
authors.lastname: Li
mesh_terms: D004247:DNA / Q000235:genetics; D019143:Evolution, Molecular; D005091:Exons; D005785:Gene Conversion; D008040:Genetic Linkage; D014644:Genetic Variation; D006801:Humans; D007438:Introns; D017299:Rod Opsins / Q000235:genetics*; D014960:X Chromosome / Q000235:genetics
chemical_list: D017299:Rod Opsins; D004247:DNA