title: [Use of mesoglycan in venous pathology].
abstract: Twenty-five female patients suffering from primary venous insufficiency of the lower limbs underwent parenteral and oral treatment with mesoglycan for 3 months. In addition to an evaluation of the subjective and objective parameters linked to venous insufficiency, all patients underwent lower limb venous echo colour-Doppler and videocapillaroscopy using an optic probe in a perimalleolar or periulcerous site. At the end of treatment, all patients reported an improvement in subjective parameters, which was confirmed by a reduction of distal edema in 22 out of 25 cases. There was also an improvement in capillaroscopic findings (reduction of edema of pericapillary connective tissue, reduction of capillary and venular ectasia.
authors.affiliation: Servizio di Angiologia, Azienda USL, Città di Bologna.
authors.forename: G
authors.initials: G
authors.lastname: Scondotto
authors.forename: G
authors.initials: G
authors.lastname: Catena
authors.forename: D
authors.initials: D
authors.lastname: Aloisi
mesh_terms: D000284:Administration, Oral; D000328:Adult; D000368:Aged; D002196:Capillaries / Q000187:drug effects; D004730:Endothelium, Vascular / Q000187:drug effects; D005260:Female; D005500:Follow-Up Studies; D006025:Glycosaminoglycans / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D007273:Injections, Intramuscular; D007866:Leg / Q000098:blood supply; D007871:Leg Ulcer / Q000000981:diagnostic imaging / Q000188:drug therapy; D008875:Middle Aged; D013997:Time Factors; D018615:Ultrasonography, Doppler, Color; D014689:Venous Insufficiency / Q000000981:diagnostic imaging / Q000188:drug therapy*; D014741:Video Recording
chemical_list: D006025:Glycosaminoglycans; C040617:mesoglycan
vernacular_title: Uso del mesoglicano in patologia venosa.