[Results of treatment with interferon for chronic hepatitis B in children].
8 children with chronic hepatitis B were treated with interferon, 3 M.U. subcutaneously three times a week for 4-5 months. Seroconversion from HBe antigen to anti HBe antibodies was observed in 3 of them and in 1 also seroconversion from HBs antigen to anti HBs antibodies. In remaining 5 cases the therapy was ineffective which could be caused by: more advanced inflammatory lesions in liver, infection with HB in infancy and low activity of aminotransferases before the treatment. Side effects of interferon were only transitory and in no case caused cessation of the therapy.
Kowalik-Mikołajewska
B
B
Kliniki Chorób Zakaźnych Wieku Dzieciecego Akademii Medycznej w Warszawie.
Ladyzyńska
E
E
Loch
T
T
Wojnarowski
M
M
D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D005260:Female; D006510:Hepatitis B Antibodies / Q000032:analysis; D019694:Hepatitis B, Chronic / Q000175:diagnosis / Q000276:immunology / Q000628:therapy*; D006801:Humans; D007279:Injections, Subcutaneous; D007372:Interferons / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male
D006510:Hepatitis B Antibodies; D007372:Interferons
Wyniki leczenia interferonem przewlekłego wirusowego zapalenia watroby typu B u dzieci.