Cartilage chondrolysis by fibronectin fragments causes cleavage of aggrecan at the same site as found in osteoarthritic cartilage.
Homandberg
G A
GA
Department of Biochemistry, Rush Medical College at Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois, USA.
Davis
G
G
Maniglia
C
C
Shrikhande
A
A
D053674:Aggrecans; D000595:Amino Acid Sequence; D000818:Animals; D002358:Cartilage, Articular / Q000187:drug effects* / Q000378:metabolism; D002417:Cattle; D046508:Culture Techniques; D016326:Extracellular Matrix Proteins; D005353:Fibronectins / Q000494:pharmacology*; D007375:Interleukin-1 / Q000494:pharmacology; D037181:Lectins, C-Type; D010003:Osteoarthritis / Q000378:metabolism*; D010446:Peptide Fragments / Q000494:pharmacology*; D011509:Proteoglycans / Q000737:chemistry / Q000378:metabolism*; D011994:Recombinant Proteins / Q000494:pharmacology
D053674:Aggrecans; D016326:Extracellular Matrix Proteins; D005353:Fibronectins; D007375:Interleukin-1; D037181:Lectins, C-Type; D010446:Peptide Fragments; D011509:Proteoglycans; D011994:Recombinant Proteins