Is the heredity of reticulate acro pigmentation of Kitamura always autosomal dominant?
Reticulate acropigmentation of Kitamura (RAK) in three patients and their families is described. In one family, 2 women and 2 men were affected out of 9 individuals. In the other family, 6 women had lesions of reticulate acropigmentation out of total of 27 over three generations. In the third family, one man was affected. All of the cases had palmar pits; onset of lesions was after puberty in all the cases. The apparently different hereditary patterns in these three families are striking, and autosomal dominant inheritance appears unlikely in every case.
Singal
A
A
Department of Dermatology & STD, University College of Medical Sciences, Delhi, India.
Bhattacharya
S N
SN
Baruah
M C
MC
Indrayan
A
A
Singh
N
N
D000169:Acrodermatitis / Q000235:genetics* / Q000473:pathology; D000293:Adolescent; D000328:Adult; D001284:Atrophy; D001706:Biopsy; D004817:Epidermis / Q000473:pathology; D005148:Facial Dermatoses / Q000235:genetics; D005260:Female; D005799:Genes, Dominant / Q000235:genetics*; D006801:Humans; D017495:Hyperpigmentation / Q000235:genetics* / Q000473:pathology; D008297:Male; D008544:Melanocytes / Q000473:pathology; D010375:Pedigree; D011627:Puberty