title: Activation of blood coagulation in patients with mitral stenosis and sinus rhythm.
abstract: The aim of this study was to assess whether there is blood coagulation activation in patients with mitral stenosis (MS) and sinus rhythm (SR) and to investigate the value of left atrial spontaneous echo contrast (LASEC) as a predictive sign of increased coagulation activity. Using thrombin-antithrombin III complexes and prothrombin fragment 1+2 as in vivo hemostatic markers, we concluded that there is a hypercoagulable state in patients with MS and SR when LASEC is present.
authors.affiliation: Department of Hematology, Hacettepe University Medical School, Ankara, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Ileri
authors.forename: Y
authors.initials: Y
authors.lastname: Büyükaşik
authors.forename: N S
authors.initials: NS
authors.lastname: Ileri
authors.forename: I C
authors.initials: IC
authors.lastname: Haznedaroglu
authors.forename: S
authors.initials: S
authors.lastname: Göksel
authors.forename: S
authors.initials: S
authors.lastname: Kirazli
authors.forename: S
authors.initials: S
authors.lastname: Dündar
mesh_terms: D000328:Adult; D000368:Aged; D001777:Blood Coagulation; D001778:Blood Coagulation Disorders / Q000097:blood* / Q000000981:diagnostic imaging / Q000503:physiopathology; D004452:Echocardiography; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D008946:Mitral Valve Stenosis / Q000097:blood* / Q000000981:diagnostic imaging / Q000503:physiopathology