Bilirubinate granules: main pathologic bile component in patients with idiopathic acute pancreatitis.
OBJECTIVE
The aim of this study was to evaluate the main pathologic component of bile obtained by biliary drainage in patients with acute idiopathic pancreatitis and therapeutic implications.


METHODS
Eighteen patients diagnosed with idiopathic acute pancreatitis underwent biliary drainage. Microscopic evaluation of bile was performed and pathologic components were classified in cholesterol microcrystals, bilirubinate granules, and calcium microspherolites.


RESULTS
Five patients showed no abnormalities. In 11 patients, bilirubinate granules were found, cholesterol microcrystals in two, and Giardia lamblia in two.


CONCLUSIONS
Bilirubinate granules are the main pathologic component of bile in patients with acute idiopathic pancreatitis. Cholecystectomy is the preferred therapeutic approach.
Pérez-Martín
G
G
Department of Internal Medicine, La Paz Hospital, Autonoma University, Madrid, Spain.
Gómez-Cerezo
J
J
Codoceo
R
R
Olveira
A
A
Conde
P
P
Garcés
M C
MC
Barbado
F J
FJ
Vázquez
J J
JJ
D000328:Adult; D000368:Aged; D001646:Bile / Q000737:chemistry*; D001663:Bilirubin / Q000032:analysis / Q000737:chemistry*; D004322:Drainage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000473:pathology*
D001663:Bilirubin