[Antiseptic efficacy and acceptance of Octenisept computed with common antiseptic mouthwashes].
The efficacy of common antiseptic mouth rinses was evaluated in a study with healthy volunteers. Octenisept and Cetylpyridiniumchlorid had a significant stronger impact on the microbial burden of the oral cavity than Chlorhexidin (Corsodyl) immediately and 10 min after the application. Dobendan (contains Cetylpyridiniumchlorid) showed a better antimicrobial effect than Corsodyl immediately after application, after 10 min an increasing loss of efficacy was noted. The antiseptic efficacy of hexetidin-based Gurfix was very similar to the efficacy observed with Corsodyl from the start of the antiseptic treatment until 1 h later. Acriflavine-solution (0.2% m/v) was significantly less efficient after 10, 30 and 60 min compared to Corsodyl. The antimicrobial impact of Fluomint-Lysoform was very similar to the effect of rinsing with dest. sterile water. A subjective assessment of taste and smell of the mouth rinse solutions concludes the evaluation. Further methodological aspects for a common test guideline for antiseptic mouth rinse solutions are discussed.
Kramer
A
A
Institut für Hygiene und Umweltmedizin, Ernst-Moritz-Arndt-Universität Greifswald.
Höppe
H
H
Krull
B
B
Pitten
F A
FA
Rosenau
S
S
D000328:Adult; D000891:Anti-Infective Agents, Local / Q000494:pharmacology; D002594:Cetylpyridinium / Q000494:pharmacology; D002710:Chlorhexidine / Q000494:pharmacology; D006590:Hexetidine / Q000494:pharmacology; D006801:Humans; D007097:Imines; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology; D009067:Mouthwashes; D011725:Pyridines / Q000494:pharmacology; D012903:Smell; D013649:Taste
D000891:Anti-Infective Agents, Local; D007097:Imines; D009067:Mouthwashes; D011725:Pyridines; D006590:Hexetidine; D002594:Cetylpyridinium; C034213:octenidine; D002710:Chlorhexidine
Antiseptische Wirksamkeit und Akzeptanz von Octenisept im Vergleich zu ausgewählten herkömmlichen Mundhöhlenantiseptika.