title: [Results of treatment with interferon for chronic hepatitis B in children].
abstract: 8 children with chronic hepatitis B were treated with interferon, 3 M.U. subcutaneously three times a week for 4-5 months. Seroconversion from HBe antigen to anti HBe antibodies was observed in 3 of them and in 1 also seroconversion from HBs antigen to anti HBs antibodies. In remaining 5 cases the therapy was ineffective which could be caused by: more advanced inflammatory lesions in liver, infection with HB in infancy and low activity of aminotransferases before the treatment. Side effects of interferon were only transitory and in no case caused cessation of the therapy.
authors.affiliation: Kliniki Chorób Zakaźnych Wieku Dzieciecego Akademii Medycznej w Warszawie.
authors.forename: B
authors.initials: B
authors.lastname: Kowalik-Mikołajewska
authors.forename: E
authors.initials: E
authors.lastname: Ladyzyńska
authors.forename: T
authors.initials: T
authors.lastname: Loch
authors.forename: M
authors.initials: M
authors.lastname: Wojnarowski
mesh_terms: D002648:Child; D002675:Child, Preschool; D004334:Drug Administration Schedule; D005260:Female; D006510:Hepatitis B Antibodies / Q000032:analysis; D019694:Hepatitis B, Chronic / Q000175:diagnosis / Q000276:immunology / Q000628:therapy*; D006801:Humans; D007279:Injections, Subcutaneous; D007372:Interferons / Q000008:administration & dosage* / Q000009:adverse effects; D008297:Male
chemical_list: D006510:Hepatitis B Antibodies; D007372:Interferons
vernacular_title: Wyniki leczenia interferonem przewlekłego wirusowego zapalenia watroby typu B u dzieci.