title: [Polymorphism analysis of 4 loci of X-chromosome in a Chinese population of the Han nationality].
abstract: OBJECTIVE
  To investigate the polymorphism of 4 loci of X-chromosome in the Hans.
  
  
  METHODS
  Using PCR-SSLP, the authors analysed the polymorphism of DXS1068, DXS7132, DXS6804 and DXS6799 in the X-chromosome in 70 randomly selected female Hans.
  
  
  RESULTS
  The number of alleles in the 4 loci were 5,5,5 and 6 respectively; there were no significant differences between the observed and estimated and genotype probabilities of the 4 loci; the estimates of heterozygosity of 4 loci were 0.6819, 0.6895, 0.7659 and 0.6483 respectively and there were no significant differences between the observed and estimated heterozygosity of the 4 loci.
  
  
  CONCLUSIONS
  The distribution of alleles and genotype probabilities of 4 loci all observe the Hardy-Weinberg equilibrium.
authors.affiliation: Department of Medical Genetics, Shandong Medical University, Jinan 250012 P. R. China.
authors.forename: X
authors.initials: X
authors.lastname: Dou
authors.forename: C
authors.initials: C
authors.lastname: Guo
authors.forename: B
authors.initials: B
authors.lastname: Chen
authors.forename: X
authors.initials: X
authors.lastname: Liu
authors.forename: Y
authors.initials: Y
authors.lastname: Zou
authors.forename: Y
authors.initials: Y
authors.lastname: Gong
mesh_terms: D044466:Asian People / Q000235:genetics*; D002681:China; D005260:Female; D006801:Humans; D011110:Polymorphism, Genetic; D014960:X Chromosome