title: Cerebellar degeneration following neuroleptic malignant syndrome.
abstract: A 55-year-old woman with a history of bipolar affective disorder developed hyperpyrexia, rigidity and depressed consciousness (neuroleptic malignant syndrome) after commencing neuroleptic therapy. On regaining consciousness, she was mute and had signs suggesting pancerebellar involvement. Hyperpyrexia, which is a cardinal feature of neuroleptic malignant syndrome, may have caused cerebellar damage. Neuroleptic malignant syndrome needs both early recognition and prompt treatment to obviate devastating complications.
authors.affiliation: Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: V
authors.initials: V
authors.lastname: Lal
authors.forename: V
authors.initials: V
authors.lastname: Sardana
authors.forename: A
authors.initials: A
authors.lastname: Thussu
authors.forename: I M
authors.initials: IM
authors.lastname: Sawhney
authors.forename: S
authors.initials: S
authors.lastname: Prabhakar
mesh_terms: D002526:Cerebellar Diseases / Q000209:etiology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009155:Mutism / Q000209:etiology*; D009459:Neuroleptic Malignant Syndrome / Q000150:complications*