Medication-induced gingival enlargement: a clinical review.
This review discusses the etiology and treatment of gingival hyperplasia. It cites evidence that medications such as phenytoin, an anticonvulsant; cyclosporine, an immunosuppressant; and numerous calcium channel blocking agents have been shown clinically and histologically to produce analogous gingival enlargements. A multiphasic approach to treating disfiguring gingival hyperplasia through mechanical and chemical plaque control, in conjunction with the surgical removal of the hyperplastic tissue, is discussed.
Silverstein
L H
LH
Department of Periodontics, Medical College of Georgia, Augusta, USA.
Garnick
J J
JJ
Szikman
M
M
Singh
B
B
D000927:Anticonvulsants / Q000009:adverse effects*; D002121:Calcium Channel Blockers / Q000009:adverse effects*; D019214:Gingival Overgrowth / Q000139:chemically induced*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*
D000927:Anticonvulsants; D002121:Calcium Channel Blockers; D007166:Immunosuppressive Agents