title: Rheumatic manifestations of scurvy. A report of two cases.
abstract: Bleeding into the muscles and joints can be the presenting manifestation of scurvy, as illustrated by two case-reports. One patient presented with hemarthrosis of the tibiotalar joint due to an insufficiency fracture and was suspected to have scurvy based on the presence of purpura and hypertrophy of the gums with loss of teeth. In the other patient, multiple hematomas in the lower limbs were found at presentation and the presence of coiled hairs suggested the diagnosis. Both patients had completely eliminated fruit and vegetables from their diet. Low levels of ascorbic acid were found in serum and urine. A full recovery was achieved in both cases under ascorbic acid supplementation.
authors.affiliation: Rheumatology and Internal Medicine Department, Robert Debré Teaching Hospital, Reims, France.
authors.forename: J
authors.initials: J
authors.lastname: Léone
authors.forename: V
authors.initials: V
authors.lastname: Delhinger
authors.forename: D
authors.initials: D
authors.lastname: Maes
authors.forename: C
authors.initials: C
authors.lastname: Scheer
authors.forename: J L
authors.initials: JL
authors.lastname: Pennaforte
authors.forename: J P
authors.initials: JP
authors.lastname: Eschard
authors.forename: J C
authors.initials: JC
authors.lastname: Etienne
mesh_terms: D000328:Adult; D001205:Ascorbic Acid / Q000097:blood / Q000652:urine; D006395:Hemarthrosis / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D012216:Rheumatic Diseases / Q000209:etiology*; D012614:Scurvy / Q000150:complications*
chemical_list: D001205:Ascorbic Acid