[Electro-functional changes in pseudo-exfoliative syndrome].
OBJECTIVE
Up to date the pathogenetic aspects of exfoliation syndrome which are not well agreed upon even though the vascular damage plays a major role.


METHODS
In order to evaluate the electrophysiological changes occurring in patients affected by exfoliation syndrome a case-control study with pattern electrofunctional examinations and oscillatory potentials from standard flash-ERG in 80 eyes affected by exfoliation syndrome with or without ocular hypertension was undertaken.


RESULTS
Some statistically significant PERG, P-PEV and OP abnormalities were found in eyes affected by exfoliation syndrome with or without ocular hypertension (p < 0.001). There is no statistically significant difference between affected and control eyes in monolateral syndrome (p > 0.05). The electrofunctional examination did not mark any statistically significant difference between eyes with and without ocular hypertension (p > 0.05).


CONCLUSIONS
The results stressed by pattern and oscillatory potentials examinations may support the hypothesis of a primitive change of the optic nerve.
Spadea
L
L
Université de l'Aquila, Italie.
Giuffre
I
I
Bianco
G
G
Karoune
M
M
D000328:Adult; D000368:Aged; D004596:Electroretinography; D005074:Evoked Potentials, Visual; D017889:Exfoliation Syndrome / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000503:physiopathology; D009991:Oscillometry; D011446:Prospective Studies
Modification des examens électrofonctionnels dans le syndrome pseudo-exfoliatif.