title: Peripheral melt of flap after laser in situ keratomileusis.
abstract: BACKGROUND
  Laser in situ keratomileusis (LASIK) is an effective procedure to correct myopia. It may have complications related to the flap, such as epithelial ingrowth and stromal melt.
  
  
  METHODS
  We report on a patient who developed extensive epithelial ingrowth and partial keratolysis of the flap following LASIK. This complication was treated by lifting the flap and removing the epithelium from within the interface.
  
  
  RESULTS
  Progressive keratolysis (stromal melt) can result in irregular astigmatism and loss of vision as well as photophobia and ciliary injection. The pathogenesis is not completely understood although the epithelial ingrowth in the interface is always present, and epithelial-stromal interaction with production of proteases may be involved.
  
  
  CONCLUSIONS
  Epithelial ingrowth may develop in the lamellar interface after LASIK and be associated with melting of the edge of the flap. This undesirable complication can be successfully managed with early surgical removal of the epithelium and proper attachment of the flap.
authors.affiliation: Centro del Laser, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Castillo
authors.forename: D
authors.initials: D
authors.lastname: Diaz-Valle
authors.forename: A R
authors.initials: AR
authors.lastname: Gutierrez
authors.forename: N
authors.initials: N
authors.lastname: Toledano
authors.forename: F
authors.initials: F
authors.lastname: Romero
mesh_terms: D000328:Adult; D003315:Cornea / Q000601:surgery*; D016039:Corneal Transplantation / Q000009:adverse effects*; D019573:Epithelium, Corneal / Q000473:pathology* / Q000601:surgery; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy; D008297:Male; D009216:Myopia / Q000601:surgery*; D011183:Postoperative Complications / Q000473:pathology* / Q000601:surgery; D012086:Reoperation; D013524:Surgical Flaps / Q000473:pathology*