Atrial myxoma syndrome mimicking Ehrmann-Sneddon syndrome.
Livedo racemosa with cerebrovascular lesions has been described as Ehrmann-Sneddon syndrome. The etiopathogenetic factors provoking the vascular lesions, however, are of high diversity reaching from mechanical to autoimmune causes. We present a male patient with typical livedo racemosa, muscle pain and feeling of coldness of the forearms. By dermatohistopathology and magnetic resonance tomography of the brain, Ehrmann-Sneddon syndrome could be confirmed. At this time a chronic streptococcal infection could be diagnosed. Antibiotics, anticoagulants and vascularity-supplying therapy improved the clinical and subjective symptoms. Six months later, the patient developed dizziness, vision disorder, hypesthesia of the right forehead, malaise and weight loss. A further diagnostic workup including echocardiography revealed a myxoma of the left atrium. This report illustrates the association of Ehrmann-Sneddon syndrome with cardiac myxoma and points out that cardiac diagnostic examination should be included when dealing with small-vessel involvement of the brain.
Weisshaar
E
E
Department of Dermatology and Venereology, University of Magdeburg, Germany.
Claus
G
G
Friedl
A
A
Gollnick
H
H
D000328:Adult; D001241:Aspirin / Q000627:therapeutic use; D001933:Brain Stem / Q000473:pathology; D003937:Diagnosis, Differential; D004452:Echocardiography; D005500:Follow-Up Studies; D006325:Heart Atria / Q000000981:diagnostic imaging / Q000473:pathology; D006338:Heart Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009232:Myxoma / Q000150:complications / Q000175:diagnosis* / Q000000981:diagnostic imaging; D010296:Parietal Lobe / Q000473:pathology; D010406:Penicillins / Q000627:therapeutic use; D010431:Pentoxifylline / Q000627:therapeutic use; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D018860:Sneddon Syndrome / Q000150:complications / Q000175:diagnosis*; D013290:Streptococcal Infections / Q000175:diagnosis; D013577:Syndrome; D014665:Vasodilator Agents / Q000627:therapeutic use
D010406:Penicillins; D010975:Platelet Aggregation Inhibitors; D014665:Vasodilator Agents; D001241:Aspirin; D010431:Pentoxifylline