Myb proteins in life, death and differentiation.
Myb transcription factors are crucial to the control of proliferation and differentiation in a number of cell types but their mechanism of action is unclear. Regulation of Myb proteins by phosphorylation and intermolecular cooperation has recently been demonstrated, together with a new role for the proteins, in the control of apoptosis.
Weston
K
K
CRC Centre for Cell and Molecular Biology, Chester Beatty Laboratories, London, UK. kathy@icr.ac.uk
D000818:Animals; D018797:Cell Cycle Proteins; D016923:Cell Death; D002454:Cell Differentiation; D002470:Cell Survival; D004268:DNA-Binding Proteins / Q000235:genetics / Q000502:physiology*; D006801:Humans; D011518:Proto-Oncogene Proteins / Q000235:genetics / Q000502:physiology*; D020598:Proto-Oncogene Proteins c-myb; D015534:Trans-Activators / Q000235:genetics / Q000502:physiology*; D014157:Transcription Factors / Q000235:genetics / Q000502:physiology*
D018797:Cell Cycle Proteins; D004268:DNA-Binding Proteins; C088831:MYBL1 protein, human; C064352:MYBL2 protein, human; D011518:Proto-Oncogene Proteins; D020598:Proto-Oncogene Proteins c-myb; D015534:Trans-Activators; D014157:Transcription Factors