[Polymorphism analysis of 4 loci of X-chromosome in a Chinese population of the Han nationality].
OBJECTIVE
To investigate the polymorphism of 4 loci of X-chromosome in the Hans.


METHODS
Using PCR-SSLP, the authors analysed the polymorphism of DXS1068, DXS7132, DXS6804 and DXS6799 in the X-chromosome in 70 randomly selected female Hans.


RESULTS
The number of alleles in the 4 loci were 5,5,5 and 6 respectively; there were no significant differences between the observed and estimated and genotype probabilities of the 4 loci; the estimates of heterozygosity of 4 loci were 0.6819, 0.6895, 0.7659 and 0.6483 respectively and there were no significant differences between the observed and estimated heterozygosity of the 4 loci.


CONCLUSIONS
The distribution of alleles and genotype probabilities of 4 loci all observe the Hardy-Weinberg equilibrium.
Dou
X
X
Department of Medical Genetics, Shandong Medical University, Jinan 250012 P. R. China.
Guo
C
C
Chen
B
B
Liu
X
X
Zou
Y
Y
Gong
Y
Y
D044466:Asian People / Q000235:genetics*; D002681:China; D005260:Female; D006801:Humans; D011110:Polymorphism, Genetic; D014960:X Chromosome