title: Demonstration of myxoid change in fine-needle aspiration of synovial sarcoma: a case report.
abstract: We report a case of synovial sarcoma with extensive myxoid change diagnosed by fine-needle aspiration. The patient is a 46-year-old woman who presented with a right paratibial mass. Aspiration cytology demonstrated a spindle cell neoplasm consistent with a synovial sarcoma but containing a prominent myxoid matrix. The clinical suspicion and cytologic diagnosis of a synovial sarcoma was confirmed by histologic and immunohistochemical findings. The cytologic differential diagnosis of spindle cell neoplasms with extensive myxoid change should be broadened to include synovial sarcoma.
authors.affiliation: Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA.
authors.forename: E J
authors.initials: EJ
authors.lastname: Moffatt
authors.forename: K
authors.initials: K
authors.lastname: Liu
authors.forename: L J
authors.initials: LJ
authors.lastname: Layfield
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism; D001707:Biopsy, Needle; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000378:metabolism; D008875:Middle Aged; D009077:Mucins / Q000378:metabolism; D013584:Sarcoma, Synovial / Q000378:metabolism / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000378:metabolism / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor; D009077:Mucins; D007633:Keratins