title: Axonal spheroids in the cochlear nucleus of normal beagle dogs.
abstract: In the course of drug evaluation studies, sporadic axonal spheroids were identified in the cochlear nucleus of 8-15-month-old Beagle dogs. These structures were identified by Bielschowski histochemical and anti-neurofilament immunohistochemical stains and by ultrastructural examination. No cellular reaction or significant neuropil alterations were associated with the presence of the spheroids. Their presence was unrelated to treatment and were considered to be an incidental background finding.
authors.affiliation: Animal Diagnostic Laboratories, Kissimmee, FL 34742, USA.
authors.forename: M V
authors.initials: MV
authors.lastname: Slayter
authors.forename: B A
authors.initials: BA
authors.lastname: Summers
authors.forename: R P
authors.initials: RP
authors.lastname: Meade
authors.forename: C A
authors.initials: CA
authors.lastname: Anderson
mesh_terms: D000818:Animals; D001369:Axons / Q000473:pathology*; D017626:Cochlear Nucleus / Q000473:pathology*; D004283:Dog Diseases / Q000473:pathology*; D004285:Dogs; D004801:Eosine Yellowish-(YS) / Q000737:chemistry; D005260:Female; D005456:Fluorescent Dyes / Q000737:chemistry; D006416:Hematoxylin / Q000737:chemistry; D006651:Histocytochemistry; D007150:Immunohistochemistry; D015994:Incidence; D008297:Male
chemical_list: D005456:Fluorescent Dyes; D004801:Eosine Yellowish-(YS); D006416:Hematoxylin