Acute hemodynamic effects of metoprolol +/- nitroglycerin in patients with biopsy-proven lymphocytic myocarditis.
We evaluated acute hemodynamic effects of metoprolol +/- nitroglycerin in 11 patients with left ventricular dysfunction and biopsy-proven lymphocytic myocarditis. Acute administration of metoprolol improved ejection phase indexes, probably through the prolongation of diastole; the addition of a vasodilator further enhanced these effects by improving arterial elastance.
Popović
Z
Z
Dedinje Cardiovascular Institute and Belgrade University Medical School, Yugoslavia.
Mirić
M
M
Vasiljević
J
J
Sagić
D
D
Bojić
M
M
Popović
A D
AD
D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000328:Adult; D004359:Drug Therapy, Combination; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008214:Lymphocytes; D008297:Male; D008790:Metoprolol / Q000494:pharmacology*; D008875:Middle Aged; D009205:Myocarditis / Q000150:complications / Q000188:drug therapy* / Q000473:pathology / Q000503:physiopathology*; D005996:Nitroglycerin / Q000494:pharmacology*; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000494:pharmacology*; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000503:physiopathology*
D000319:Adrenergic beta-Antagonists; D014665:Vasodilator Agents; D005996:Nitroglycerin; D008790:Metoprolol