The vasoactive intestinal peptide analogue RO25-1553 inhibits the production of TNF and IL-12 by LPS-activated monocytes.
Dewit
D
D
Laboratory of Experimental Immunology, Medical School, Université Libre de Bruxelles, Brussels, Belgium.
Gourlet
P
P
Amraoui
Z
Z
Vertongen
P
P
Willems
F
F
Robberecht
P
P
Goldman
M
M
D006801:Humans; D016753:Interleukin-10 / Q000096:biosynthesis; D018664:Interleukin-12 / Q000037:antagonists & inhibitors* / Q000096:biosynthesis; D008070:Lipopolysaccharides / Q000494:pharmacology*; D008934:Mitogens / Q000494:pharmacology*; D009000:Monocytes / Q000187:drug effects* / Q000378:metabolism; D010456:Peptides, Cyclic / Q000494:pharmacology*; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors* / Q000096:biosynthesis; D014660:Vasoactive Intestinal Peptide / Q000031:analogs & derivatives* / Q000494:pharmacology
D008070:Lipopolysaccharides; D008934:Mitogens; D010456:Peptides, Cyclic; C089777:Ro 25-1553; D014409:Tumor Necrosis Factor-alpha; D016753:Interleukin-10; D018664:Interleukin-12; D014660:Vasoactive Intestinal Peptide