Influence of blood transfusion on bactericidal activity of human leukocytes and sera against Yersinia enterocolitica and Salmonella typhimurium.
Patients undergoing joint surgery and blood transfusion were studied. Serum and leukocyte bactericidal tests in vitro against Salmonella typhimurium and Yersinia enterocolitica were carried out preoperatively as well as on the 1st, 3rd and 7th days after the operation. The serum complement (C3 and C4) concentrations were determined at the same intervals. It was found that after blood transfusion the bactericidic activity of sera and the serum C3 complement concentrations were increased. In contrast the killing ability of leukocytes was suppressed.
Markova
N
N
Institute of Microbiology, Bulgarian Academy of Sciences, Sofia.
Radoucheva
T
T
Kussovski
V
V
Dilova
K
K
Shtarbova
M
M
Paskaleva
I
I
D001770:Blood Bactericidal Activity / Q000276:immunology / Q000502:physiology*; D001804:Blood Transfusion, Autologous / Q000009:adverse effects*; D002478:Cells, Cultured; D015169:Colony Count, Microbial; D003176:Complement C3 / Q000032:analysis; D003181:Complement C4 / Q000032:analysis; D006801:Humans; D007596:Joints / Q000601:surgery; D007694:Killer Cells, Natural / Q000276:immunology / Q000382:microbiology; D007962:Leukocytes / Q000276:immunology* / Q000382:microbiology; D012486:Salmonella typhimurium / Q000276:immunology*; D015008:Yersinia enterocolitica / Q000276:immunology*
D003176:Complement C3; D003181:Complement C4