[Insertion mutation 22w of Drosophila melanogaster blocks the cell cycle in metaphase].
We studied the cytogenetic effect of P[lArB] transposon insertion into the 42A region of the second D. melanogaster chromosome (mutation 22w). This mutation was shown to induce metaphase (rarer anaphase) block of the cell cycle. The chromosomes have an abnormal "lump" morphology. Possible involvement of the corresponding gene product in functioning of the cell oscillator is discussed.
Omel'ianchuk
L V
LV
Institute of Cytology and Genetics, Siberian Division, Russian Academy of Sciences, Novosibirsk, Russia.
Lebedeva
L I
LI
D000818:Animals; D002453:Cell Cycle / Q000235:genetics*; D002874:Chromosome Mapping; D004251:DNA Transposable Elements; D004331:Drosophila melanogaster / Q000235:genetics*; D005260:Female; D005804:Genes, Lethal; D007621:Karyotyping; D008297:Male; D008677:Metaphase / Q000235:genetics*; D016254:Mutagenesis, Insertional
D004251:DNA Transposable Elements
Insertsionnaia mutatsiia 22w Drosophila melanogaster blokiruet kletochnyĭ tsikl v metafaze.