Fatal myocardial infarction associated with bromocriptine for postpartum lactation suppression.
Bromocriptine (Parlodel) has attracted widespread controversy for its use for postpartum lactation suppression because of recent reports of cerebral and cardiovascular complications. This case describes a maternal death in which bromocriptine therapy may have triggered myocardial infarction in a patient with asymptomatic coronary artery disease. We suggest its use with caution, especially in patients with identifiable risk factors of coronary artery disease or arteriovascular disease.
Dutt
S
S
Department of Obstetrics and Gynaecology, Bankstown/Lidcombe Hospital, Sydney, New South Wales.
Wong
F
F
Spurway
J H
JH
D000328:Adult; D001971:Bromocriptine / Q000009:adverse effects* / Q000627:therapeutic use; D003328:Coronary Thrombosis / Q000150:complications; D017809:Fatal Outcome; D005260:Female; D006727:Hormone Antagonists / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D007774:Lactation / Q000187:drug effects*; D009203:Myocardial Infarction / Q000139:chemically induced*; D011644:Puerperal Disorders / Q000139:chemically induced*
D006727:Hormone Antagonists; D001971:Bromocriptine