title: Cat, dog, and house-dust-mite allergen levels of house dust in Finnish apartments.
abstract: The presence of indoor allergens in Finnish homes was studied for the first time. Dust samples (n = 30) were collected by vacuuming a 1 m2 area from a living-room carpet in 30 apartments divided into three groups: homes with cats (n = 10), homes with dogs (n = 10), and homes without pets (n = 10). The levels of major cat (Fel d 1), dog (Can f 1), and house-dust-mite (Der p 1) allergens were analyzed by two-site ELISA methods. Der p 1 levels were below the detection limit in all dust samples. In the homes with cats or dogs, Fel 1 d and Can f 1 levels ranged from 147 to 2800 micrograms/g (geometric mean 296 micrograms/g), respectively, 567 micrograms/g), and from 86 to 1400 micrograms/g (geometric mean 296 micrograms/g), respectively, being slightly higher than those reported elsewhere. Low allergen levels, mainly below 3 micrograms/g were also detected in the homes without pets, indicating the transfer of allergens from place to place. However, in 25% of these samples, allergen levels exceeded the proposed threshold levels for cat or dog sensitization. The presence of pets was the most significant factor affecting cat and dog allergen levels in the house dust, and other factors, such as the amount of dust collected, residential time, and cleaning habits, had no or only a weak effect on allergen levels.
authors.affiliation: University of Kuopio, Department of Environmental Sciences, Finland.
authors.forename: P
authors.initials: P
authors.lastname: Raunio
authors.forename: A L
authors.initials: AL
authors.lastname: Pasanen
authors.forename: M
authors.initials: M
authors.lastname: Reiman
authors.forename: T
authors.initials: T
authors.lastname: Virtanen
mesh_terms: D000485:Allergens / Q000032:analysis*; D000818:Animals; D039741:Antigens, Dermatophagoides; D052179:Antigens, Plant; D004391:Dust / Q000032:analysis; D005387:Finland; D006023:Glycoproteins / Q000032:analysis*; D006798:Housing; D006801:Humans
chemical_list: D000485:Allergens; D039741:Antigens, Dermatophagoides; D052179:Antigens, Plant; D004391:Dust; D006023:Glycoproteins; C091462:allergen Can f I; C059296:Fel d 1 protein, Felis domesticus