title: The impact of ischemic heart disease on main pulmonary artery blood flow patterns: a comparison between magnetic resonance phase velocity mapping and transesophageal color Doppler.
abstract: OBJECTIVE
  To give a detailed evaluation on main pulmonary artery blood velocity patterns, in patients with ischemic heart disease and to provide recommendations for pulsed Doppler sample volume placement, in order to optimize cardiac output estimation.
  
  
  METHODS
  Using magnetic resonance phase and esophageal color Doppler velocity mapping in 12 patients with ischemic heart disease and undergoing coronary artery by-pass grafting, very similar data on pulmonary artery blood velocity patterns were provided for comparison with each other.
  
  
  RESULTS
  Peak blood velocities were located in the inferior half of the main pulmonary artery cross-sectional area. Early after peak systole the highest velocities shifted towards the superior/left (major curvature) with a simultaneous decrease in velocities inferiorly. The velocity decrease further evolved into retrograde flow to the inferior/right (minor curvature). This feature was significantly enhanced compared to earlier findings in healthy volunteers. The mean temporal blood velocity profiles were asymmetrically skewed, thereby giving unreliable cardiac output estimates based on single point Doppler blood velocity recordings. The error incurred may amount to more than 100% in extreme cases. According to our data, optimal assessment of cardiac output should be based on multiple sample volumes placed along the inferior/right to superior/left diameter.
  
  
  CONCLUSIONS
  MR-phase velocity mapping and multiplane transesophageal color Doppler recordings provided similar blood velocity patterns in patients with ischemic heart disease. The skewness of the mean temporal blood velocity profile is enhanced compared with healthy subjects, resulting in error in the assessment of CO by means of pulsed Doppler echocardiography. By using multiple Doppler sample volumes, the error can be minimized.
authors.affiliation: Department of Anaesthesia, Aarhus Kommune Hospital, Denmark.
authors.forename: E
authors.initials: E
authors.lastname: Sloth
authors.forename: M
authors.initials: M
authors.lastname: Kruse
authors.forename: K C
authors.initials: KC
authors.lastname: Houlind
authors.forename: E M
authors.initials: EM
authors.lastname: Pedersen
authors.forename: J M
authors.initials: JM
authors.lastname: Hasenkam
mesh_terms: D000368:Aged; D018618:Echocardiography, Doppler, Color; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000503:physiopathology*; D011651:Pulmonary Artery; D012039:Regional Blood Flow; D012815:Signal Processing, Computer-Assisted