No link between avascular necrosis of the femoral head and antiphospholipid antibodies.
The rate of occurrence of antiphospholipid antibodies was compared in 47 patients with avascular necrosis of the femoral head and in 47 controls matched on age and sex. Antiphospholipid antibodies were looked for using three techniques in each patient, namely the VDRL test, an ELISA for anticardiolipin, and a circulating anticoagulant detection procedure involving three different tests. The VDRL and the tests for circulating anticoagulants were negative in all the patients and controls. No significant between-group difference was found for the ELISA, which was positive in three patients and two controls.
Dromer
C
C
Rheumatology Department, Purpan Teaching Hospital, Toulouse, France.
Marc
V
V
Laroche
M
M
Sixou
L
L
Oksman
F
F
Bon
E
E
Cantagrel
A
A
Fournié
B
B
Mazières
B
B
D000328:Adult; D000368:Aged; D017153:Antibodies, Anticardiolipin / Q000097:blood*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005271:Femur Head Necrosis / Q000276:immunology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
D017153:Antibodies, Anticardiolipin