Subretinal perfluorodecalin toxicity.
BACKGROUND
Subretinal injection of perfluorocarbon liquids (PFCL) can occur during vitreoretinal surgery. The long-term effects of this complication are not well established.


METHODS
A case report is presented of a patient with retained subretinal perfluorodecalin following retinal detachment repair for a giant retinal tear.


RESULTS
In the early postoperative period, the macular retinal pigment epithelium (RPE) became opalescent in appearance and by 2 months postoperatively the patient developed macular RPE atrophy with resulting poor central vision.


CONCLUSIONS
Toxicity of subretinal perfluorodecalin causing RPE atrophy is proposed. We recommend all traces of PFCL should be removed if possible.
Lee
G A
GA
Royal Brisbane Hospital, Herston, Queensland, Australia.
Finnegan
S J
SJ
Bourke
R D
RD
D001284:Atrophy / Q000139:chemically induced / Q000473:pathology; D005260:Female; D005451:Fluorescein Angiography; D005466:Fluorocarbons / Q000008:administration & dosage / Q000009:adverse effects*; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D007267:Injections; D008266:Macula Lutea / Q000187:drug effects*; D008875:Middle Aged; D010857:Pigment Epithelium of Eye / Q000473:pathology*; D012163:Retinal Detachment / Q000150:complications / Q000601:surgery; D012164:Retinal Diseases / Q000139:chemically induced* / Q000473:pathology; D012167:Retinal Perforations / Q000209:etiology / Q000601:surgery; D014792:Visual Acuity; D014821:Vitrectomy
D005466:Fluorocarbons; C008805:perfluorodecalin