title: Risks of silicosis in coalworkers exposed to unusual concentrations of respirable quartz.
abstract: OBJECTIVE
  To describe the radiographic changes in coalworkers exposed to unusual concentrations of respirable quartz during the 1970s, and to relate these to exposure measurements.
  
  
  METHODS
  Men who had worked at one Scottish colliery during the 1970s were invited to a health survey. Chest radiographs were taken from 547 subjects. Classifications of these films under the International Labour Organisation (ILO) 1980 scheme were related, by logistic regression, to existing data on individual men's exposures to respirable dust and quartz.
  
  
  RESULTS
  Taking the median of the three readers' results on profusion of small opacities, 203 men (38%) showed progression of at least one profusion category on the 12 point scale, from the various 1970s surveys to the follow up in 1990-1. A total of 158 men (29%) had a profusion of at least 1/0, and 47 (8.6%) of at least 2/1 at the follow up survey. Large opacities were recorded as present by at least two readers for 14 (2.6%) of the men. Profusion of small opacities was strongly related to exposures experienced in the 1970s, and more strongly for quartz than for the non-quartz fraction of the dust. Estimates of risk are presented over the range of quartz exposures experienced.
  
  
  CONCLUSIONS
  The quartz exposures experienced by some men at this colliery have caused considerable progression of radiographic abnormalities since exposure ended. The data accumulated offer opportunities for further more detailed analyses to inform debate on occupational limits for quartz exposures, both in collieries and in other industries where there is exposure to quartz in mixed dust.
authors.affiliation: Institute of Occupational Medicine, Edinburg, UK.
authors.forename: B G
authors.initials: BG
authors.lastname: Miller
authors.forename: S
authors.initials: S
authors.lastname: Hagen
authors.forename: R G
authors.initials: RG
authors.lastname: Love
authors.forename: C A
authors.initials: CA
authors.lastname: Soutar
authors.forename: H A
authors.initials: HA
authors.lastname: Cowie
authors.forename: M W
authors.initials: MW
authors.lastname: Kidd
authors.forename: A
authors.initials: A
authors.lastname: Robertson
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D003032:Coal Mining; D018450:Disease Progression; D004305:Dose-Response Relationship, Drug; D004391:Dust / Q000009:adverse effects; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects; D011791:Quartz / Q000008:administration & dosage / Q000009:adverse effects*; D011859:Radiography; D012829:Silicosis / Q000000981:diagnostic imaging / Q000209:etiology*; D012907:Smoking
chemical_list: D004391:Dust; D011791:Quartz