Effects of anesthetics on Fos protein expression in autonomic brain nuclei related to cardiovascular regulation.
We tested the influence of urethane, chloral hydrate and a mixture of ketamine/xylazine on Fos protein expression in autonomic brain regions related to blood pressure. We conclude that ketamine/xylazine is a suitable anesthetic to be used in studies looking at c-fos expression in neural circuits serving cardiovascular regulation.
Rocha
M J
MJ
Department of Physiology, University of Tübingen, Germany. mjrocha@rfi.fmrp.usp.br
Herbert
H
H
D000777:Anesthetics / Q000494:pharmacology*; D018681:Anesthetics, General / Q000494:pharmacology; D000818:Animals; D001341:Autonomic Nervous System / Q000187:drug effects / Q000378:metabolism*; D001921:Brain / Q000033:anatomy & histology / Q000187:drug effects / Q000502:physiology*; D002697:Chloral Hydrate / Q000494:pharmacology; D006439:Hemodynamics / Q000187:drug effects / Q000502:physiology*; D007150:Immunohistochemistry; D007649:Ketamine / Q000494:pharmacology; D008297:Male; D016760:Proto-Oncogene Proteins c-fos / Q000096:biosynthesis*; D051381:Rats; D017207:Rats, Sprague-Dawley; D014520:Urethane / Q000494:pharmacology; D014991:Xylazine / Q000494:pharmacology
D000777:Anesthetics; D018681:Anesthetics, General; D016760:Proto-Oncogene Proteins c-fos; D014991:Xylazine; D014520:Urethane; D002697:Chloral Hydrate; D007649:Ketamine