title: Nucleotide sequence of canine herpesvirus homologues of herpes simplex virus type 1 US2, US3, glycoproteins I and E, US8.5 and US9 genes.
abstract: The partial nucleotide sequence of two BamHI fragments that span the unique short region (US), terminal repeat region (TR) and internal repeat region (IR) of canine herpesvirus (CHV) has been determined. Data obtained revealed several open reading frames (ORF's) identified as the US2, US3, gI, gE and US9 homologues of herpes simplex virus type 1 (HSV1). The CHV homologues also show significant identity in amino acid sequence with those encoded by feline herpesvirus type 1 (FHV1), bovine herpesvirus (BHV1) and equine herpesvirus (EHV1). Translation of another ORF showed little amino acid identity with the gene products of other alpha-herpesviruses. Its genomic position relative to the other CHV homologues would suggest it is the US8.5 gene of CHV.
authors.affiliation: CSIRO Division of Animal Health, Australian Animal Health Laboratory, Geelong, Australia.
authors.forename: S G
authors.initials: SG
authors.lastname: Tyack
authors.forename: M J
authors.initials: MJ
authors.lastname: Studdert
authors.forename: M A
authors.initials: MA
authors.lastname: Johnson
mesh_terms: D018138:Alphaherpesvirinae / Q000235:genetics; D000595:Amino Acid Sequence; D006023:Glycoproteins / Q000235:genetics*; D007242:Herpesvirus 1, Bovine / Q000235:genetics; D002184:Herpesvirus 1, Canid / Q000235:genetics*; D008969:Molecular Sequence Data; D016366:Open Reading Frames; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid; D014759:Viral Envelope Proteins / Q000235:genetics*
chemical_list: D006023:Glycoproteins; D014759:Viral Envelope Proteins; C044768:glycoprotein E, herpes simplex virus type 1; C064959:glycoprotein I, herpes simplex virus type 1