Renal effects of renin-angiotensin system blockade.
Pharmacological interruption of the renin-angiotensin system at different pathway levels has extended our knowledge on the distribution of angiotensin receptors in different nephron segments, its regulation and tubular cell responses. Novel beneficial effects obtained with blockade of this peptide on cellular proliferation and its interaction with other vasoactive systems are particularly important for preventing renal damage.
Franco
M
M
Department of Nephrology, Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico.
Paniagua
R
R
Herrera-Acosta
J
J
D000804:Angiotensin II / Q000502:physiology; D001808:Blood Vessels / Q000502:physiology; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007668:Kidney / Q000254:growth & development / Q000502:physiology*; D007684:Kidney Tubules / Q000502:physiology; D011945:Receptors, Angiotensin / Q000502:physiology; D012079:Renal Circulation / Q000502:physiology; D012084:Renin-Angiotensin System / Q000502:physiology*
D011945:Receptors, Angiotensin; D000804:Angiotensin II