Non-diabetic end-stage renal disease among Saskatchewan aboriginal people.
OBJECTIVE
To determine the rates, causes and outcomes of non-diabetic end-stage renal disease (ESRD) among aboriginal and non-aboriginal people in Saskatchewan.


METHODS
Retrospective population-based study using data from the Canadian Organ Replacement Register.


METHODS
Saskatchewan.


METHODS
All patients with non-diabetic ESRD diagnosed between Jan. 1, 1981, and Dec. 31, 1990.


METHODS
Age- and sex-specific as well as age-adjusted incidence rates of non-diabetic ESRD among aboriginal and non-aboriginal people in Saskatchewan, causes of non-diabetic ESRD, mortality rates, causes of death and renal transplantation rates.


RESULTS
The 10-year incidence rates of non-diabetic ESRD were higher in all age groups among aboriginal people than among non-aboriginal people. The overall risk ratio for aboriginal people was 2.56. Aboriginal people experienced non-diabetic ESRD at an earlier age and were twice as likely to have a form of glomerulonephritis as a cause. Crude mortality rates, causes of death and transplantation rates were similar in the 2 populations, although we were unable to adjust these for differences in age.


CONCLUSIONS
Although diabetes is the most common cause of ESRD among aboriginal people in Saskatchewan, this population also experiences an excessive burden of non-diabetic ESRD, which is largely explained by a higher rate of glomerulonephritis.
Dyck
R F
RF
Department of Medicine, College of Medicine, University of Saskatchewan, Saskatoon.
Tan
L
L
D000367:Age Factors; D044467:American Indian or Alaska Native / Q000706:statistics & numerical data*; D048909:Diabetes Complications; D005260:Female; D005921:Glomerulonephritis / Q000150:complications; D006801:Humans; D007676:Kidney Failure, Chronic / Q000453:epidemiology* / Q000401:mortality; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors; D012525:Saskatchewan; D012737:Sex Factors