title: Porous polyethylene sheet implant with a barrier surface: a rabbit study.
abstract: Soft tissue adhesion to the porous polyethylene sheet implant (PPSI) raises the concern of postoperative extraocular motility disturbance after orbital blowout fracture repairs using PPSI. A PPSI with a barrier surface (PPSI-B) has been developed to reduce adhesion between soft tissue and the implant. Six PPSI-B and six conventional PPSI were implanted under the scalps of three New Zealand white rabbits. The implants were harvested at 2-, 4-, and 20-week intervals. Clinical and histologic comparisons were made between PPSI-B and PPSI with regard to adhesion at the soft tissue-implant interface. Clinically, PPSI-B demonstrated less adhesion between soft tissue and implant compared with the conventional PPSI. Both types of implants demonstrated a complete fibrovascular ingrowth by 2 weeks. Because PPSI-B causes less adhesion at the soft tissue-implant interface, consideration should be given to the use of PPSI-B in repairs of orbital blowout fractures in which extraocular muscle is exposed to the implant surface.
authors.affiliation: Brigham and Women's Hospital, Boston, Massachusetts, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Choi
authors.forename: S
authors.initials: S
authors.lastname: Bstandig
authors.forename: M A
authors.initials: MA
authors.lastname: Iwamoto
authors.forename: P A
authors.initials: PA
authors.lastname: Rubin
authors.forename: J W
authors.initials: JW
authors.lastname: Shore
mesh_terms: D000818:Animals; D005260:Female; D005500:Follow-Up Studies; D016348:Osseointegration; D011095:Polyethylenes; D016062:Porosity; D011183:Postoperative Complications / Q000473:pathology / Q000517:prevention & control; D019736:Prostheses and Implants; D019919:Prosthesis Implantation; D011817:Rabbits; D012535:Scalp / Q000601:surgery; D000267:Tissue Adhesions / Q000473:pathology* / Q000517:prevention & control
chemical_list: D011095:Polyethylenes