title: [Possibility of using saliva for therapeutic monitoring of digoxin].
abstract: Digoxin in salvia and blood serum of 24 patients obtained Bemecor was determined by the method of FPIA (IMx-ABBOT). Mixed saliva was collected by three different types of Salivette (Sarstedt) given in order: normal Salivette with cotton wool swab, Slivette with polyester wool and Salivette with citric acid as a stimulator. It was found, that the correletio between the digoxin concentrations in saliva and serum and saliva/serum rations depended on the type of Salivette. The highest correlation was obtained with the Salivette with polyester wool (r = 0.892), but low concentrations of this drug in serum were good reflected in all samples of saliva, independent on kind of Salivette.
authors.affiliation: Zakładu Diagnostyki Laboratoryjnej CMKP, Warszawie.
authors.forename: W
authors.initials: W
authors.lastname: Tadeusiak
authors.forename: E
authors.initials: E
authors.lastname: Marcinowska-Suchowierska
authors.forename: J
authors.initials: J
authors.lastname: Podleśny
authors.forename: A
authors.initials: A
authors.lastname: Andrzejewski
mesh_terms: D004077:Digoxin / Q000032:analysis* / Q000097:blood; D005260:Female; D006801:Humans; D008297:Male; D008520:Medigoxin / Q000008:administration & dosage / Q000378:metabolism; D012463:Saliva / Q000737:chemistry*; D013048:Specimen Handling / Q000379:methods*
chemical_list: D004077:Digoxin; D008520:Medigoxin
vernacular_title: Mozliwość zastosowania śliny do terapii monitorowanej digoksyny.