title: Soluble vascular cell adhesion molecule-1 and E-selectin in patients with acute myocardial infarction treated with thrombolytic agents.
abstract: Twenty-three patients enrolled in th GUSTO-III study underwent serial measurements of soluble vascular cell adhesion molecule-1 (VCAM-1) and E-selectin by enzyme-linked immunosorbent assay at prespecified time intervals. Soluble VCAM-1, but not E-selectin levels, were increased in patients with acute myocardial infarction, indicating that VCAM-1 may serve as a marker of increased endothelial activation in acute myocardial infarction.
authors.affiliation: Union Memorial Hospital, Baltimore, Maryland 21218, USA.
authors.forename: P A
authors.initials: PA
authors.lastname: Gurbel
authors.forename: V L
authors.initials: VL
authors.lastname: Serebruany
mesh_terms: D000368:Aged; D019040:E-Selectin / Q000097:blood*; D005260:Female; D005343:Fibrinolytic Agents / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood* / Q000188:drug therapy*; D010960:Plasminogen Activators / Q000627:therapeutic use; D011994:Recombinant Proteins / Q000627:therapeutic use; D015912:Thrombolytic Therapy; D013997:Time Factors; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use; D019010:Vascular Cell Adhesion Molecule-1 / Q000097:blood*
chemical_list: D019040:E-Selectin; D005343:Fibrinolytic Agents; D011994:Recombinant Proteins; D019010:Vascular Cell Adhesion Molecule-1; C087896:reteplase; D010960:Plasminogen Activators; D010959:Tissue Plasminogen Activator