title: [Antiseptic efficacy and acceptance of Octenisept computed with common antiseptic mouthwashes].
abstract: The efficacy of common antiseptic mouth rinses was evaluated in a study with healthy volunteers. Octenisept and Cetylpyridiniumchlorid had a significant stronger impact on the microbial burden of the oral cavity than Chlorhexidin (Corsodyl) immediately and 10 min after the application. Dobendan (contains Cetylpyridiniumchlorid) showed a better antimicrobial effect than Corsodyl immediately after application, after 10 min an increasing loss of efficacy was noted. The antiseptic efficacy of hexetidin-based Gurfix was very similar to the efficacy observed with Corsodyl from the start of the antiseptic treatment until 1 h later. Acriflavine-solution (0.2% m/v) was significantly less efficient after 10, 30 and 60 min compared to Corsodyl. The antimicrobial impact of Fluomint-Lysoform was very similar to the effect of rinsing with dest. sterile water. A subjective assessment of taste and smell of the mouth rinse solutions concludes the evaluation. Further methodological aspects for a common test guideline for antiseptic mouth rinse solutions are discussed.
authors.affiliation: Institut für Hygiene und Umweltmedizin, Ernst-Moritz-Arndt-Universität Greifswald.
authors.forename: A
authors.initials: A
authors.lastname: Kramer
authors.forename: H
authors.initials: H
authors.lastname: Höppe
authors.forename: B
authors.initials: B
authors.lastname: Krull
authors.forename: F A
authors.initials: FA
authors.lastname: Pitten
authors.forename: S
authors.initials: S
authors.lastname: Rosenau
mesh_terms: D000328:Adult; D000891:Anti-Infective Agents, Local / Q000494:pharmacology; D002594:Cetylpyridinium / Q000494:pharmacology; D002710:Chlorhexidine / Q000494:pharmacology; D006590:Hexetidine / Q000494:pharmacology; D006801:Humans; D007097:Imines; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology; D009067:Mouthwashes; D011725:Pyridines / Q000494:pharmacology; D012903:Smell; D013649:Taste
chemical_list: D000891:Anti-Infective Agents, Local; D007097:Imines; D009067:Mouthwashes; D011725:Pyridines; D006590:Hexetidine; D002594:Cetylpyridinium; C034213:octenidine; D002710:Chlorhexidine
vernacular_title: Antiseptische Wirksamkeit und Akzeptanz von Octenisept im Vergleich zu ausgewählten herkömmlichen Mundhöhlenantiseptika.