title: Hoarseness and gastroesophageal reflux in children.
abstract: The importance of a hoarse voice or voice change in children has not been stressed in the literature in the same way as it has been in adults. We present 21 children who had been suffering from chronic hoarseness for more than three months and had on fibre-optic laryngoscopy findings suggestive of gastroesophageal reflux. None of them had complained of gastroesophageal symptoms. Twenty-four hour pH monitoring revealed that 13 (62 per cent) of these children had gastroesophageal reflux, seven (33 per cent) having gastroesophageal reflux more than three times the upper limit of normal. The pH graphs highlighted frequent refluxes, ranging from 0.4 to 37.4 refluxes per hour (median of 7.3 refluxes/hour). The majority of these refluxes occurred when the child was awake as opposed to asleep, with a median of 14.8 refluxes/hour and 0.9 refluxes/hour respectively (p = 0.0009). The refluxes were classically of short duration. This study suggests that gastroesophageal reflux plays a direct role in the pathogenesis of chronic laryngitis and hoarseness in children.
authors.affiliation: Department of Oto-rhino-laryngology, Hôpital Saint Vincent de Paul, Faculté Cochin Paris, France.
authors.forename: L
authors.initials: L
authors.lastname: Gumpert
authors.forename: N
authors.initials: N
authors.lastname: Kalach
authors.forename: C
authors.initials: C
authors.lastname: Dupont
authors.forename: P
authors.initials: P
authors.lastname: Contencin
mesh_terms: D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D004947:Esophagus / Q000378:metabolism; D005260:Female; D005336:Fiber Optic Technology; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000378:metabolism; D006685:Hoarseness / Q000209:etiology* / Q000378:metabolism; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007828:Laryngoscopy; D008297:Male