Repetition priming in normal aging and Alzheimer's disease: a review of findings and theories.
On repetition priming tasks, memory is measured indirectly as a change in performance due to recent experience. It is often functionally and neurally dissociated from performance on explicit memory tasks, which directly measure conscious recall or recognition of recent events. Repetition priming has therefore been extensively studied in normal aging and Alzheimer's disease, which feature mild to severe changes in explicit memory. Initial studies indicated that repetition priming was immune to the effects of aging and greatly reduced in Alzheimer's disease (AD). As more studies have been performed, however, these initial conclusions appear less clear than before and, in the case of AD, actually misleading. The purpose of this article is to provide a comprehensive review of this rapidly expanding literature, articulate the issues that are critical to interpreting the empirical results, and discuss what new conclusions are suggested by the overall pattern of findings.
Fleischman
D A
DA
Department of Neurological Sciences, Rush Medical College, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612, USA. dfleisch@rush.edu
Gabrieli
J D
JD
D000368:Aged; D000375:Aging / Q000523:psychology*; D000544:Alzheimer Disease / Q000523:psychology*; D003071:Cognition; D003463:Cues; D005260:Female; D006801:Humans; D008297:Male; D008606:Mental Processes; D011939:Mental Recall; D008875:Middle Aged; D011932:Reading; D012153:Retention, Psychology