title: [Dimethylsulfoxide (DMSO) in horses: a literature review].
abstract: The use of dimethyl sulphoxide in equine medicine is discussed with special reference to trauma of the central nervous system, chronic endometritis, trauma of the locomotor apparatus, and ischaemic bowel pathophysiology. The ability of dimethyl sulphoxide to reduce connective tissue formation might be of interest in abdominal surgery. The anti-inflammatory effect of dimethyl sulphoxide is used in the treatment of muscle trauma, tendinitis, laminitis, and arthritis. Dimethyl sulphoxide can potentiate the effects of other drugs. The most common dose is 1 g/kg body weight intravenously up to a 40%-solution with a maximum duration of treatment of 5 days. Dimethyl sulphoxide has not been approved for use in horses in the Netherlands.
authors.affiliation: Vakgroep Inwendige Ziekten en Voeding der Grote Huisdieren, Utrecht.
authors.forename: R A
authors.initials: RA
authors.lastname: Douwes
authors.forename: J H
authors.initials: JH
authors.lastname: van der Kolk
mesh_terms: D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D002493:Central Nervous System Diseases / Q000188:drug therapy / Q000662:veterinary; D004066:Digestive System Diseases / Q000188:drug therapy / Q000662:veterinary; D004121:Dimethyl Sulfoxide / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D005298:Fertility / Q000187:drug effects; D006734:Horse Diseases / Q000188:drug therapy*; D006736:Horses; D008297:Male; D009140:Musculoskeletal Diseases / Q000188:drug therapy / Q000662:veterinary
chemical_list: D000893:Anti-Inflammatory Agents; D004121:Dimethyl Sulfoxide
vernacular_title: Dimethylsulfoxide (DMSO) bij het paard: een literatuuroverzicht.