title: Lipoblastoma: a case with t(7;8)(q31;q13).
abstract: Lipoblastoma is a rare benign adipose tumor which, in all of the cases so far described, presents an involvement of chromosome 8 in the region 8q11-13. We hereby report the results of the second case of lipoblastoma studied by fluorescence in situ hybridization (FISH), in a 13-month-old boy. An abnormal karyotype 46,XY,t(7;8)(q31;q13) was found in 90% of the metaphases examined, in agreement with the previously reported observations. We suggest the region 8q11-13 may contain a relevant locus for lipoblastoma origin.
authors.affiliation: Department of Pediatric Hematology/Oncology, Giannina Gaslini Institute, Genova, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Panarello
authors.forename: C
authors.initials: C
authors.lastname: Rosanda
authors.forename: C
authors.initials: C
authors.lastname: Morerio
authors.forename: I
authors.initials: I
authors.lastname: Russo
authors.forename: S
authors.initials: S
authors.lastname: Dallorso
authors.forename: C
authors.initials: C
authors.lastname: Gambini
authors.forename: A S
authors.initials: AS
authors.lastname: Ricco
authors.forename: T
authors.initials: T
authors.lastname: Storlazzi
authors.forename: N
authors.initials: N
authors.lastname: Archidiacono
authors.forename: M
authors.initials: M
authors.lastname: Rocchi
mesh_terms: D002897:Chromosomes, Human, Pair 7; D002898:Chromosomes, Human, Pair 8; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007223:Infant; D007621:Karyotyping; D008067:Lipoma / Q000235:genetics* / Q000473:pathology; D008297:Male; D014178:Translocation, Genetic