title: [Anesthetic management of a patient with antiphospholipid syndrome].
abstract: A 46-year-old woman with antiphospholipid syndrome (APS) underwent an emergent laparotomy. The symptoms and signs of APS are reported to be thrombosis, habitual abortion, thrombocytopenia and biological false positive (BFP) for syphilis' tests. Clinical symptoms are based on hypercoagulation of blood, while prothrombin time (PT) activity and activated partial thromboplastin time (APTT) are prolonged. Although we have selected general endotracheal anesthesia without epidural catheterization, we recommend that the regional analgesia is suitable for those APS patients with abnormality of coagulation. If PT and APTT differ from clinical symptoms, we have to think about APS and manage the patients carefully as APS.
authors.affiliation: Department of Anesthesiology, Shizuoka General Hospital.
authors.forename: Y
authors.initials: Y
authors.lastname: Seima
authors.forename: Y
authors.initials: Y
authors.lastname: Shiraishi
authors.forename: S
authors.initials: S
authors.lastname: Sakai
authors.forename: J
authors.initials: J
authors.lastname: Yokoyama
authors.forename: H
authors.initials: H
authors.lastname: Igarashi
authors.forename: T
authors.initials: T
authors.lastname: Kimura
mesh_terms: D000768:Anesthesia, General; D016736:Antiphospholipid Syndrome / Q000097:blood / Q000150:complications*; D004630:Emergencies; D005260:Female; D006801:Humans; D007416:Intestinal Perforation / Q000150:complications / Q000601:surgery; D007813:Laparotomy; D008875:Middle Aged; D010314:Partial Thromboplastin Time; D010976:Platelet Count; D011517:Prothrombin Time