title: Hyperhomocysteinemia as a cause of premature stroke in a young patient.
abstract: A case is presented of a woman who had an occlusive stroke at age 29. She was seen in a rehabilitation medicine clinic for central nervous system-mediated pain that had developed soon after a cerebrovascular event. After an extensive workup to find the cause of her cerebrovascular occlusion, it was discovered that she had a markedly elevated fasting plasma homocysteine level of 59 micromol/L. A discussion of premature vascular disease in the rehabilitation patient is followed by a short review of the clinical detection of, and potential therapy for, hyperhomocysteinemia.
authors.affiliation: Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
authors.forename: J G
authors.initials: JG
authors.lastname: Ray
authors.forename: D T
authors.initials: DT
authors.lastname: Harvey
mesh_terms: D000328:Adult; D017668:Age of Onset; D002561:Cerebrovascular Disorders / Q000097:blood / Q000209:etiology*; D005260:Female; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D010148:Intractable Pain / Q000209:etiology
chemical_list: D006710:Homocysteine