title: Neuromuscular disorders and acute respiratory failure.
abstract: This article discusses the assessment and management of rapidly progressive weakness due to neuromuscular disorders. The authors review elements helpful in determining the causes of weakness including pertinent history and laboratory studies. Disorders are classified according to the level of the motor unit involved and triage/management decisions are described. In addition, respiratory function assessment is reviewed. The latter part of this article is devoted to evaluation and management of two of the most common disorders, Guillain-Barré syndrome and myasthenia gravis.
authors.affiliation: Department of Neurology, University of Massachusetts Medical Center, Worcester, Massachusetts, USA.
authors.forename: I
authors.initials: I
authors.lastname: Bella
authors.forename: D A
authors.initials: DA
authors.lastname: Chad
mesh_terms: D003937:Diagnosis, Differential; D004630:Emergencies; D006801:Humans; D009157:Myasthenia Gravis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D009460:Neurologic Examination; D009468:Neuromuscular Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D010348:Patient Care Team; D011129:Polyradiculoneuropathy / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D011379:Prognosis; D012131:Respiratory Insufficiency / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012307:Risk Factors