Lung cancer risk due to exposure to incorporated plutonium.
An epidemiological study has been carried out among 1,479 male workers who started working at the "Mayak" Production Association in 1948-1958 and were exposed to external gamma radiation and plutonium aerosols. Lung cancer mortality for the follow-up period 1948-1993 has been analyzed. No statistically significant association of lung cancer mortality and external gamma-ray dose has been revealed in the range of accumulated doses of 0.2-5.5 Gy. Association of lung cancer mortality and the dose of alpha-particle radiation to the lung is statistically significant. In the dose range below 30 Sv, this association can be described in terms of a linear nonthreshold function. Lifetime lung cancer risk in the dose range below 30 Sv is 1.21 x 10(-2)Sv(-1).
Koshurnikova
N A
NA
Branch No. 1 of the State Scientific Center Biophysics Institute, Ozyorsk, Chelyabinsk region, Russia.
Bolotnikova
M G
MG
Ilyin
L A
LA
Keirim-Markus
I B
IB
Menshikh
Z S
ZS
Okatenko
P V
PV
Romanov
S A
SA
Tsvetkov
V I
VI
Shilnikova
N S
NS
D000328:Adult; D000336:Aerosols; D000367:Age Factors; D000368:Aged; D000512:Alpha Particles; D004307:Dose-Response Relationship, Radiation; D005720:Gamma Rays; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology* / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced; D016273:Occupational Exposure; D011005:Plutonium; D012042:Registries; D012306:Risk
D000336:Aerosols; D011005:Plutonium