[Relationship between activity of atrial natriuretic peptide and process of myocardial remodelling in patients with cardiac failure].
Echocardioscopy in M- and B-modes with measurement of routine parameters of central hemodynamics and thickness of carotid intimal-medial segment as well as radioimmunoassay of plasma concentrations of atrial natriuretic peptide (ANUP) were performed in 159 patients aged 42-63 years (17 healthy subjects and 142 patients with cardiac failure associated with ischemic heart disease and sinus rhythm, without history of myocardial infarction). The results were indicative of possible use of ANUP as a marker of initial cardiac insufficiency and a corrector of the disease prognosis.
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D000328:Adult; D009320:Atrial Natriuretic Factor / Q000097:blood* / Q000378:metabolism; D015415:Biomarkers / Q000097:blood; D002302:Cardiac Output; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D004452:Echocardiography; D006325:Heart Atria / Q000000981:diagnostic imaging / Q000378:metabolism*; D006333:Heart Failure / Q000097:blood* / Q000150:complications / Q000503:physiopathology; D006801:Humans; D008875:Middle Aged; D009200:Myocardial Contraction; D017202:Myocardial Ischemia / Q000097:blood / Q000150:complications / Q000503:physiopathology; D011379:Prognosis; D011863:Radioimmunoassay; D018487:Ventricular Dysfunction, Left / Q000097:blood* / Q000150:complications / Q000503:physiopathology
D015415:Biomarkers; D009320:Atrial Natriuretic Factor
Sviaz' aktivnosti predserdnogo natriĭureticheskogo peptida i protsessov remodelirovaniia miokarda u bol'nykh s serdechoĭ nedostatochnost'iu.