Intravenous immunoglobulin therapy in a child with cutaneous polyarteritis nodosa.
Cutaneous polyarteritis nodosa (CPAN) may have a prolonged recurrent course which needs chronic corticosteroids treatment to achieve remission. In this report we describe a 9 year old boy who developed CPAN, which we treated with high dose intravenous immunoglobulin (IVIG), with an immediate favourable response. We discuss the advantages of IVIG over corticosteroids and speculate on its pathogenesis and mechanism of action.
Uziel
Y
Y
Department of Pediatrics, Hospital for Sick Children, University of Toronto, Canada.
Silverman
E D
ED
D002648:Child; D004305:Dose-Response Relationship, Drug; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage; D008297:Male; D010488:Polyarteritis Nodosa / Q000473:pathology / Q000628:therapy*; D012867:Skin / Q000098:blood supply*
D016756:Immunoglobulins, Intravenous