title: Biological effects of low-level exposures: a perspective from U.S. EPA scientists.
abstract: Biological effects of low-level exposures (BELLE) may be very important in characterizing the potential health risks of environmental pollutants. Before some features of BELLE, such as effects that may be modulated by adaptive or defense mechanisms, can be taken into greater consideration in U.S. Environmental Protection Agency risk assessments, however adequate information on a toxicant's mode of action and answers to other questions are needed.
authors.affiliation: National Center for Environmental Assessment, U.S. Environmental Protection Agency, Research Triangle Park, NC 27711, USA. davis.jmichael@epamail.epa.gov
authors.forename: J M
authors.initials: JM
authors.lastname: Davis
authors.forename: W H
authors.initials: WH
authors.lastname: Farland
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D004305:Dose-Response Relationship, Drug; D004785:Environmental Pollutants / Q000633:toxicity*; D006801:Humans; D018570:Risk Assessment; D014481:United States; D014484:United States Environmental Protection Agency
chemical_list: D004785:Environmental Pollutants