An atlas of serpin conformations.
The serpins are a family of proteins that inhibit chymotrypsin-like serine proteinases, with an unusual mechanism involving a large conformational change known as the stressed-->relaxed (S-->R) transition. This article is a guide to the known serpin conformations and their biological significance.
Whisstock
J
J
Department of Haematology, University of Cambridge, MRC Centre, UK.
Skinner
R
R
Lesk
A M
AM
D000595:Amino Acid Sequence; D000818:Animals; D006801:Humans; D008958:Models, Molecular; D008969:Molecular Sequence Data; D011487:Protein Conformation; D015843:Serpins / Q000737:chemistry* / Q000235:genetics
D015843:Serpins