title: Eczematous hypersensitivity from aqueous vitamin K injection.
abstract: Hypoprothrombinemic states are commonly treated with injectable vitamin K. Cutaneous vitamin K hypersensitivity can manifest as eczematous or sclerodermoid lesions and historically has been related to the use of fat-soluble vitamin K1. We present a case of warfarin-induced hypoprothrombinemia treated with aqueous vitamin K1, which resulted in the appearance of eczematous vitamin K1 hypersensitivity.
authors.affiliation: Department of Dermatology, Brooke Army Medical Center, Fort Sam Houston, Texas 78234-6200, USA.
authors.forename: G C
authors.initials: GC
authors.lastname: Keough
authors.forename: J C
authors.initials: JC
authors.lastname: English
authors.forename: J J
authors.initials: JJ
authors.lastname: Meffert
mesh_terms: D000328:Adult; D004485:Eczema / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D006801:Humans; D007020:Hypoprothrombinemias / Q000188:drug therapy; D007279:Injections, Subcutaneous; D014812:Vitamin K / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D014812:Vitamin K