title: [Propofol and sevoflurane--a comparison of anesthesia for laryngomicrosurgery].
abstract: Laryngomicrosurgery has some special characteristics. It is under much stress such as intubation and direct laryngoscopy during a short operation time. Therefore both adequate anesthesia and quick recovery are needed. Thirty three ASA physical status I patients for laryngomicrosurgery were randomly assigned to receive either anesthesia with propofol and small dose of fentanyl (Group P) or anesthesia with thiopental and sevoflurane (Group S). Group P was induced with propofol 2-3 mg.kg-1 and fentanyl 0.1 mg and maintained with propofol 6 mg.kg-1.h-1 (from 10 mg.kg-1.h-1 by 2 mg.kg-1.h-1 decrement in interval of 10 minutes). No intravenous analgesic was added. Group S was induced with thiopental 4 -5 mg.kg-1 and maintained with sevoflurane 2-3%. We compared emergence time and the state of recovery 5 minutes after extubation and 5 minutes after entering the recovery room. There was no episode of inadequate anesthetic state in both groups. The emergence time was significantly shorter in Group P than in Group S. The state of recovery was much better in Group P compared with Group S in both 5 minutes after extubation and 5 minutes after entering the recovery room. Therefore, anesthesia with propofol and small dose of fentanyl at induction is more adequate compared with anesthesia with sevoflurane in laryngomicrosurgery.
authors.affiliation: Department of Anesthesiology, Tokyo Senbai Hospital.
authors.forename: M
authors.initials: M
authors.lastname: Nishimori
authors.forename: M
authors.initials: M
authors.lastname: Takasaki
authors.forename: T
authors.initials: T
authors.lastname: Akune
authors.forename: K
authors.initials: K
authors.lastname: Hanaoka
mesh_terms: D000293:Adolescent; D000328:Adult; D000762:Anesthesia Recovery Period; D000768:Anesthesia, General; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D004724:Endoscopy; D005260:Female; D005283:Fentanyl; D006801:Humans; D007825:Laryngectomy; D007828:Laryngoscopy; D008297:Male; D008738:Methyl Ethers; D008866:Microsurgery; D008875:Middle Aged; D013517:Otorhinolaryngologic Surgical Procedures; D015742:Propofol; D000077149:Sevoflurane; D013874:Thiopental; D013997:Time Factors
chemical_list: D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D008738:Methyl Ethers; D000077149:Sevoflurane; D013874:Thiopental; D005283:Fentanyl; D015742:Propofol