title: (R)-3,N-dimethyl-N-[1-methyl-3-(4-methyl-piperidin-1-yl) propyl]benzenesulfonamide: the first selective 5-HT7 receptor antagonist.
authors.affiliation: Department of Medicinal Chemistry, SmithKline Beecham Pharmaceuticals, Harlow, Essex, England.
authors.forename: I T
authors.initials: IT
authors.lastname: Forbes
authors.forename: S
authors.initials: S
authors.lastname: Dabbs
authors.forename: D M
authors.initials: DM
authors.lastname: Duckworth
authors.forename: A J
authors.initials: AJ
authors.lastname: Jennings
authors.forename: F D
authors.initials: FD
authors.lastname: King
authors.forename: P J
authors.initials: PJ
authors.lastname: Lovell
authors.forename: A M
authors.initials: AM
authors.lastname: Brown
authors.forename: L
authors.initials: L
authors.lastname: Collin
authors.forename: J J
authors.initials: JJ
authors.lastname: Hagan
authors.forename: D N
authors.initials: DN
authors.lastname: Middlemiss
authors.forename: G J
authors.initials: GJ
authors.lastname: Riley
authors.forename: D R
authors.initials: DR
authors.lastname: Thomas
authors.forename: N
authors.initials: N
authors.lastname: Upton
mesh_terms: D000262:Adenylyl Cyclases / Q000378:metabolism; D001667:Binding, Competitive; D002460:Cell Line; D015870:Gene Expression; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010880:Piperidines / Q000138:chemical synthesis* / Q000494:pharmacology; D011985:Receptors, Serotonin / Q000187:drug effects* / Q000235:genetics / Q000502:physiology; D012702:Serotonin Antagonists / Q000138:chemical synthesis* / Q000494:pharmacology; D013237:Stereoisomerism; D013329:Structure-Activity Relationship; D013449:Sulfonamides / Q000138:chemical synthesis* / Q000494:pharmacology; D000096926:Benzenesulfonamides
chemical_list: D000262:Adenylyl Cyclases; D010880:Piperidines; D011985:Receptors, Serotonin; D012702:Serotonin Antagonists; D013449:Sulfonamides; C111309:3,N-dimethyl-N-(1-methyl-3-(4-methylpiperidin-1-yl)propyl)benzenesulfonamide; D000096926:Benzenesulfonamides; C104425:serotonin 7 receptor