title: Unusual MRI findings in grey matter heterotopia.
abstract: We report unusual MRI patterns in patients with grey matter heterotopia. Standard T1- and T2-weighted spin-echo and inversion-recovery sequences were used in 22 patients presenting with seizures or developmental delay. The images were reviewed for signal change surrounding white matter and for atypical size, morphology or topography. We found 10 cases of subependymal heterotopias 11 of focal subcortical heterotopia and of diffuse subcortical heterotopia. On clinical or MRI grounds, 8 cases were considered unusual: 2 of the subependymal type, 2 of focal subcortical heterotopia with white matter abnormalities, 2 of focal subcortical heterotopia with no clinicoradiological correlation 1 of extensive hemispheric subcortical heterotopia and 1 of diffuse subcortical heterotopia confined to the frontal lobe. The classical classification of heterotopia enables easy radiological diagnosis even in cases with unusual patterns. In some cases, heterogeneity and high signal in surrounding white matter can be found. Cortical dysplasia is the most frequent associated malformation.
authors.affiliation: Service de Neuroradiologie, Hôpital Roger Salengro, CHRU, Lille, France.
authors.forename: G
authors.initials: G
authors.lastname: Soto Ares
authors.forename: M
authors.initials: M
authors.lastname: Hamon-Kerautret
authors.forename: C
authors.initials: C
authors.lastname: Houlette
authors.forename: O
authors.initials: O
authors.lastname: Godefroy
authors.forename: X
authors.initials: X
authors.lastname: Leclerc
authors.forename: J P
authors.initials: JP
authors.lastname: Pruvo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001921:Brain / Q000473:pathology; D001927:Brain Diseases / Q000175:diagnosis* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D002828:Choristoma / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged