title: [Sclerosing adenosis of the prostate].
abstract: OBJECTIVE
  To describe the anatomoclinical characteristics of 4 cases of sclerosing adenosis of the prostate in order to determine the diagnostic features and clinical significance of this disease entity, which histologically mimicks adenocarcinoma of the prostate.
  
  
  METHODS
  Specimens from our Pathological Anatomy Service obtained by transurethral resection (TUR) and prostatic adenomectomy, with a clinical diagnosis of a benign pathology, were reviewed. Three cases with a histological diagnosis of sclerosing adenosis of the prostate were found over the last 10 years. A fourth case, an adenomectomy specimen corresponding to 1986 whose initial diagnosis had been changed to that of sclerosing adenosis of the prostate, was identified in a review conducted on incidentally detected carcinomas Tla.
  
  
  RESULTS
  The four cases (2 adenomectomy, 2 TUR specimens) were microscopic findings. Patient mean age was 73 years. All cases were associated with a nodular hyperplasia, without clinical or analytical signs of malignant neoplasm or an associated carcinoma. One case showed involvement of 3 fragments of the TUR specimen; the rest had a single focus or involvement of a single fragment. At 5 years mean follow-up, no evidence of new lesions have been observed.
  
  
  CONCLUSIONS
  Sclerosing adenosis of the prostate is an uncommon lesion, which is generally microscopic and more frequently found in the prostatic transitional zone, and can be confused histologically with microacinar carcinoma. It is usually an incidental histopathological finding without clinical significance or relationship with carcinoma of the prostate.
authors.affiliation: Servicio de Anatomía Patológica, Hospital Ntra. Sra. del Pino, Las Palmas de Gran Canaria, España.
authors.forename: E
authors.initials: E
authors.lastname: Redonodo Martínez
authors.forename: A R
authors.initials: AR
authors.lastname: López
authors.forename: M
authors.initials: M
authors.lastname: de la Vega Pérez
authors.forename: M V
authors.initials: MV
authors.lastname: Sánchez Lobo
mesh_terms: D000368:Aged; D006801:Humans; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000473:pathology*
vernacular_title: Adenosis esclerosante de la próstata.