title: [Granulomatous slack skin].
abstract: A 48-year-old woman developed granulomatous slack skin (GSS), one of the special forms of cutaneous T-cell lymphoma. The lesional skin slack with an atrophic, poikilodermic surface and granulomatous induration. Histopathological findings included epidermotropism, diffuse lymphoid cell infiltration and foreign body giant cells as well as granulomatous reactions from superficial to deep dermis, including part the subcutis. The diagnosis was established by positive results for rearrangement of the T-cell receptor gene. The therapeutic possibilities, especially with corticosteroids and monitoring the disease course by following serum angiotensin converting enzyme activity are discussed.
authors.affiliation: Dermatologische Abteilung, Tokai Universität, Kanagawa, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Kawakubo
authors.forename: H
authors.initials: H
authors.lastname: Shinagawa
authors.forename: M
authors.initials: M
authors.lastname: Akamatsu
authors.forename: M
authors.initials: M
authors.lastname: Iizuka
authors.forename: Y
authors.initials: Y
authors.lastname: Tsutsumi
authors.forename: M
authors.initials: M
authors.lastname: Ohkido
mesh_terms: D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis / Q000235:genetics / Q000473:pathology; D005260:Female; D015329:Gene Rearrangement, T-Lymphocyte / Q000235:genetics; D015743:Giant Cells, Foreign-Body / Q000473:pathology; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D008875:Middle Aged; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology
vernacular_title: "Granulomatous slack skin".