title: Nucleotide sequence of a highly conserved region of the canine p53 tumour suppressor gene.
abstract: An evolutionary conserved region of the canine tumour suppressor gene, p53, was PCR amplified and its DNA sequence determined. The 1003 bp fragment consisted of exons 5 to 8 and the intervening introns. A high level of sequence homology was demonstrated with human sequences, with the evolutionary conserved domains II, III, IV and V being identical.
authors.affiliation: Department of Veterinary Clinical Studies, University of Glasgow Veterinary School, Scotland, U.K.
authors.forename: L
authors.initials: L
authors.lastname: Nasir
authors.forename: D J
authors.initials: DJ
authors.lastname: Argyle
authors.forename: S T
authors.initials: ST
authors.lastname: McFarlane
authors.forename: S W
authors.initials: SW
authors.lastname: Reid
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D017124:Conserved Sequence; D004285:Dogs; D005091:Exons; D016158:Genes, p53; D006801:Humans; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D012689:Sequence Homology, Nucleic Acid