Pravastatin-induced lichenoid drug eruption.
Although drug eruptions caused by pravastatin and other lovastatin analogs have previously been described, reports of lichenoid eruptions are rare. We report a patient whose lichenoid lesions developed after initiation, resolved on discontinuation, and reappeared on rechallenge with pravastatin therapy. A brief review of lichenoid drug eruptions and skin lesions due to 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors is discussed.
Keough
G C
GC
Department of Dermatology, Brooke Army Medical Center, Fort Sam Houston, Texas 78234-6200, USA.
Richardson
T T
TT
Grabski
W J
WJ
D000368:Aged; D000924:Anticholesteremic Agents / Q000009:adverse effects*; D003937:Diagnosis, Differential; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects*; D017512:Lichenoid Eruptions / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D017035:Pravastatin / Q000009:adverse effects*
D000924:Anticholesteremic Agents; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D017035:Pravastatin