Genitourinary cancers in older adults.
Prostate and bladder carcinoma are, in large part, diseases of older adults, and they are discussed in this context. Pathology, diagnosis, and staging are reviewed. Surgical and medical approaches to these malignancies, and the limitations of these approaches, are highlighted. Renal cell carcinoma, while a relatively rare neoplasm, remains a formidable challenge: approximately 50% of patients die within 5 years of diagnosis. Advances in molecular genetics and histopathologic classification, as well as surgical management and investigational therapies, are emphasized.
Morganstern
D
D
Section of Medical Oncology, St. Elizabeth's Medical Center, Boston, Massachusetts 02135, USA.
Garnick
M B
MB
D000368:Aged; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D002295:Carcinoma, Transitional Cell / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D008297:Male; D011471:Prostatic Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy