title: [P73: a kin to the p52 tumor suppressor gene].
abstract: A gene with remarkable sequence homology with the tumour suppressor gene p53 is located at the tip of the short arm of human chromosome 1 which is often found to be deleted in neuroblastomas, melanomas and breast cancers. Despite their structural and functional similarities, p53 and p73 may have distinct roles in cell grow regulation.
authors.affiliation: Sanofi Recherche, Labège Innopole.
authors.forename: D
authors.initials: D
authors.lastname: Caput
mesh_terms: D002455:Cell Division / Q000235:genetics / Q000502:physiology; D002878:Chromosomes, Human, Pair 1; D004268:DNA-Binding Proteins / Q000235:genetics / Q000502:physiology; D016147:Genes, Tumor Suppressor; D006801:Humans; D009447:Neuroblastoma / Q000235:genetics; D009687:Nuclear Proteins / Q000235:genetics / Q000502:physiology; D000072160:Tumor Protein p73; D016159:Tumor Suppressor Protein p53 / Q000235:genetics / Q000502:physiology; D025521:Tumor Suppressor Proteins
chemical_list: D004268:DNA-Binding Proteins; D009687:Nuclear Proteins; C000606460:TP73 protein, human; D000072160:Tumor Protein p73; D016159:Tumor Suppressor Protein p53; D025521:Tumor Suppressor Proteins
vernacular_title: p73: un cousin du gène suppresseur de tumeur p53.