HLA antigens in asthmatic children.
The purpose of the present study was to analyze the frequency of HLA-DR and DQ antigens in Brazilian asthmatic children with skin-test and RAST positivity to Dermatophagoides pteronyssinus. The comparison of HLA-DR and DQ antigenic frequencies between patients (n = 30) and controls disclosed a significantly higher HLA-DQ2 frequency in the patients (60% versus 34%, p = 0.013; R. R. = 2.8).
Gerbase-DeLima
M
M
Department of Pediatrics, Escola Paulista de Medicina, Universidade Federal de São Paulo, Brazil.
Gallo
C A
CA
Daher
S
S
Solé
D
D
Naspitz
C K
CK
D000293:Adolescent; D001249:Asthma / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006683:HLA-DQ Antigens / Q000032:analysis* / Q000737:chemistry; D006684:HLA-DR Antigens / Q000032:analysis* / Q000737:chemistry; D006801:Humans; D008297:Male
D006683:HLA-DQ Antigens; D006684:HLA-DR Antigens