title: Benign prostatic hyperplasia in older men.
abstract: Urinary tract symptoms secondary to benign prostatic hyperplasia (BPH) may adversely affect quality of life in many older men. Evaluation of patients with BPH should be focused on excluding complicating factors such as urinary tract infection, renal dysfunction, and malignancy. Watchful waiting is an appropriate option for men in whom such complicating conditions have been excluded. For those men who elect to be treated, therapy using alpha blockers (terazosin, doxazosin) or 5-alpha reductase inhibitors (finasteride) should be offered initially. Surgical treatment is generally reserved for patients who do not have a sufficient response to medical therapy and those with absolute indications for intervention, such as complete retention, recurrent infection or hematuria, renal insufficiency, and bladder stones.
authors.affiliation: Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, Illinois 60637, USA.
authors.forename: G S
authors.initials: GS
authors.lastname: Gerber
mesh_terms: D058891:5-alpha Reductase Inhibitors; D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use; D000368:Aged; D004791:Enzyme Inhibitors / Q000627:therapeutic use; D006801:Humans; D015994:Incidence; D008297:Male; D011468:Prostatectomy; D011470:Prostatic Hyperplasia / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D016055:Urinary Retention / Q000209:etiology
chemical_list: D058891:5-alpha Reductase Inhibitors; D000317:Adrenergic alpha-Antagonists; D004791:Enzyme Inhibitors