Semen quality and sex hormones with reference to metal welding.
Welding may involve hazards to the male reproductive system, but previous studies of semen quality have produced inconsistent results. We studied the effects of welding on markers of semen quality in a Danish nationwide sample of 430 first-time pregnancy planners without earlier reproductive experience. Couples were recruited among members of the union of metal workers and three other trade unions and were followed from termination of birth control until pregnancy for a maximum of six menstrual cycles. The males provided semen samples in each cycle. Median sperm density for welders was 56 x 10(6)/mL (52.5 x 10(6)/mL and 50.0 x 10(6)/mL in two reference groups). No statistically significant differences attributable to welding were found in proportions of morphologically normal sperm, sperm motility assessed by computer-aided sperm analysis, or sex hormones (testosterone, follicle-stimulating hormone, and luteinizing hormone). These negative findings may not apply to populations with high-level exposure to welding fume or to welders exposed to other putative hazards, e.g., heat.
Hjollund
N H
NH
Department of Occupational Medicine, Aarhus University Hospital, Denmark.
Bonde
J P
JP
Jensen
T K
TK
Ernst
E
E
Henriksen
T B
TB
Kolstad
H A
HA
Giwercman
A
A
Skakkebaek
N E
NE
Olsen
J
J
D000328:Adult; D002857:Chromium / Q000009:adverse effects* / Q000097:blood; D003718:Denmark; D005260:Female; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008297:Male; D016273:Occupational Exposure; D011247:Pregnancy; D012661:Semen / Q000187:drug effects*; D013076:Sperm Count / Q000187:drug effects; D013081:Sperm Motility / Q000187:drug effects; D013094:Spermatozoa / Q000187:drug effects*; D013739:Testosterone / Q000097:blood; D014896:Welding
D002857:Chromium; D013739:Testosterone; D007986:Luteinizing Hormone; D005640:Follicle Stimulating Hormone