title: Genetic selection of alcohol preference can be countered by conditioning processes.
abstract: Twenty-four P rats and 24 NP rats were conditioned to consume 10% w/v alcohol in daily 0.5-h limited access periods using a modified version of Samson's sucrose fading procedure. Both P and NP rats demonstrated a strikingly similar day-to-day pattern of alcohol intakes. For the most part, P rats drank more than NP rats, but by the middle of the fourth month of drinking, P and NP rats were drinking equivalent amounts of alcohol. Both P and NP rats consumed alcohol in amounts similar to two outbred strains of rats (Wistar and Sprague-Dawley) previously conditioned to drink alcohol in this laboratory.
authors.affiliation: Department of Psychiatry & Behavioral Sciences, University of Oklahoma Health Sciences Center, Oklahoma City 73190-3000, USA. dgauvin@rex.re.uokhsc.edu
authors.forename: D V
authors.initials: DV
authors.lastname: Gauvin
authors.forename: S A
authors.initials: SA
authors.lastname: Vanecek
authors.forename: T J
authors.initials: TJ
authors.lastname: Baird
authors.forename: R J
authors.initials: RJ
authors.lastname: Briscoe
authors.forename: M
authors.initials: M
authors.lastname: Vallett
authors.forename: F A
authors.initials: FA
authors.lastname: Holloway
mesh_terms: D000428:Alcohol Drinking / Q000235:genetics*; D000818:Animals; D003213:Conditioning, Psychological; D000431:Ethanol / Q000008:administration & dosage; D005518:Food Preferences; D008297:Male; D051381:Rats; D017207:Rats, Sprague-Dawley; D017208:Rats, Wistar; D012996:Solutions; D013395:Sucrose / Q000008:administration & dosage
chemical_list: D012996:Solutions; D000431:Ethanol; D013395:Sucrose