Prolongation of allograft survival of transfected islets expressing human CTLA4-Ig, human soluble Fas ligand or a combination of the two.
Gainer
A L
AL
Department of Medicine, University of Alberta, Edmonton, Canada.
Suarez-Pinzon
W L
WL
Min
W P
WP
Hancock-Friesen
C
C
Korbutt
G S
GS
Rajotte
R V
RV
Rabinovitch
A
A
Warnock
G L
GL
Elliott
J F
JF
D000069594:Abatacept; D000276:Adjuvants, Immunologic / Q000235:genetics; D000818:Animals; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000235:genetics / Q000276:immunology*; D060908:CTLA-4 Antigen; D003921:Diabetes Mellitus, Experimental / Q000276:immunology / Q000601:surgery*; D053222:Fas Ligand Protein; D018014:Gene Transfer Techniques; D006085:Graft Survival / Q000235:genetics / Q000276:immunology*; D006801:Humans; D018796:Immunoconjugates; D007515:Islets of Langerhans / Q000502:physiology; D016381:Islets of Langerhans Transplantation; D008562:Membrane Glycoproteins / Q000235:genetics / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D014184:Transplantation, Homologous
D000276:Adjuvants, Immunologic; D015703:Antigens, CD; D000943:Antigens, Differentiation; D060908:CTLA-4 Antigen; C556706:CTLA4 protein, human; C556707:Ctla4 protein, mouse; C505661:FASLG protein, human; D053222:Fas Ligand Protein; C505658:Fasl protein, mouse; D018796:Immunoconjugates; D008562:Membrane Glycoproteins; D000069594:Abatacept