[Collagen nephritis].
Fibrillar collagen in the glomeruli is considered specific of the nail-patella syndrome. A new nephropathy with diffuse intraglomerular deposition of type III collagen without nail and skeletal abnormalities has been described. We report the case of a 26-year-old woman who presented persistent proteinuria, hematuria, deafness without nail and skeletal abnormalities. The renal biopsy showed focal and segmental glomerulosclerosis by light microscopy. The electron microscopy revealed the presence of massive fibrillar collagen within the mesangial matriz and the basement membrane. This is the first patient reported in our country. We emphasize the usefulness of electron microscopy in the study of glomerular diseases.
Lago
N R
NR
Departamento de Patología, Facultad de Medicina, Universidad de Buenos Aires, Argentina.
Bulos
M J
MJ
Monserrat
A J
AJ
D000328:Adult; D003095:Collagen Diseases / Q000473:pathology*; D005260:Female; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology*; D008854:Microscopy, Electron; D009393:Nephritis / Q000473:pathology*
Nefritis colágena.