title: The role of 99m-Tc HMPAO SPECT in the diagnosis of Creutzfeldt-Jacob disease.
abstract: A patient with acute dementia underwent imaging of the brain with technetium-99m hexamethylpropyleneamine oxime single-photon emission computed tomography. Regional perfusion abnormalities were identified in multiple locations, particularly in the left frontal lobe. This information was used to direct an open brain biopsy, which led to a diagnosis of Creutzfeldt-Jacob disease.
authors.affiliation: Department of Radiology, Pennsylvania Hospital, Philadelphia, USA.
authors.forename: D A
authors.initials: DA
authors.lastname: Miller
authors.forename: R A
authors.initials: RA
authors.lastname: Vitti
authors.forename: M M
authors.initials: MM
authors.lastname: Maslack
mesh_terms: D001706:Biopsy; D002560:Cerebrovascular Circulation / Q000502:physiology; D007562:Creutzfeldt-Jakob Syndrome / Q000000981:diagnostic imaging* / Q000503:physiopathology; D005260:Female; D005625:Frontal Lobe / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D019690:Technetium Tc 99m Exametazime; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D019690:Technetium Tc 99m Exametazime