title: Myofibroblastoma associated with bilateral gynecomastia: a case report and literature review.
abstract: Myofibroblastoma of the breast is a recently recognized benign mesenchymal mammary tumor that typically occurs as a unilateral, solitary lesion. Myofibroblastomas are well-circumscribed, unencapsulated tumors characterized by spindle cells in fascicles which exhibit varying degrees of myogenic and fibroblastic differentiation. Our case reports a mammary myofibroblastoma occurring in an 82-year-old male with gynecomastia and reviews the reported incidence of this benign spindle cell tumor in the world literature.
authors.affiliation: Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.
authors.forename: C C
authors.initials: CC
authors.lastname: Yoo
authors.forename: J C
authors.initials: JC
authors.lastname: Pui
authors.forename: M H
authors.initials: MH
authors.lastname: Torosian
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D018952:Antigens, CD34 / Q000032:analysis; D018567:Breast Neoplasms, Male / Q000737:chemistry / Q000150:complications* / Q000473:pathology; D003893:Desmin / Q000032:analysis; D005260:Female; D006177:Gynecomastia / Q000150:complications* / Q000473:pathology; D006801:Humans; D008297:Male; D009379:Neoplasms, Muscle Tissue / Q000737:chemistry / Q000150:complications* / Q000473:pathology
chemical_list: D018952:Antigens, CD34; D003893:Desmin