Identification of the anthracycline antibiotic 4-O-(beta-D-glucopyranuronosyl)-epsilon-rhodomycinone, produced by Streptomyces ruber JCM3131, as an up-regulator of MHC class-I molecules in B16/BL6 cells.
Komatsu
Y
Y
Pharmaceuticals & Biotechnology Laboratory, Japan Energy Corporation, Saitama, Japan.
Takahashi
O
O
Hayashi
H
H
D000818:Animals; D000903:Antibiotics, Antineoplastic / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D015395:Histocompatibility Antigens Class I / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy; D008546:Melanoma, Experimental / Q000276:immunology; D051379:Mice; D009279:Naphthacenes / Q000737:chemistry* / Q000302:isolation & purification* / Q000494:pharmacology; D013302:Streptomyces / Q000737:chemistry*; D015854:Up-Regulation
D000903:Antibiotics, Antineoplastic; D006027:Glycosides; D015395:Histocompatibility Antigens Class I; D009279:Naphthacenes; C047545:4-O-(glucopyranosyl)-epsilon-rhodomycinone