title: Prevention of local scar formation after operative discectomy for lumbar disc herniation.
abstract: This was a prospective study. The study evaluated the use of Preclude Spinal Membrane to inhibit peridural fibrosis and reduce fibroses-related problems after first-time lumbar discectomy. Peridural scarring causes tethering of dura and nerve roots. Following discectomy Preclude Spinal Membrane was applied to patients of first group (10 patients). The second group (10 patients) was operated on without Preclude Spinal Membrane. Outcome was evaluated with MRI, 3 and 6 month after operation for all patients. No peridural or epidural scar tissue could be found in patients with Preclude Spinal Membrane, in the control group who were operated on without the preclude Spinal Membrane scar tissue of varying degree with complete enclosure of the nerve roots and dura was found.
authors.affiliation: Department of Neurosurgery, University of Innsbruck, Austria.
authors.forename: I
authors.initials: I
authors.lastname: Mohsenipour
authors.forename: M
authors.initials: M
authors.lastname: Daniaux
authors.forename: F
authors.initials: F
authors.lastname: Aichner
authors.forename: K
authors.initials: K
authors.lastname: Twerdy
mesh_terms: D000328:Adult; D002921:Cicatrix / Q000517:prevention & control*; D017586:Diskectomy; D006801:Humans; D007405:Intervertebral Disc Displacement / Q000175:diagnosis / Q000601:surgery*; D008159:Lumbar Vertebrae / Q000473:pathology / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008567:Membranes, Artificial; D008875:Middle Aged; D010865:Pilot Projects; D011183:Postoperative Complications / Q000517:prevention & control*; D011446:Prospective Studies; D016896:Treatment Outcome
chemical_list: D008567:Membranes, Artificial