title: Ventricular late potentials, interstitial fibrosis, and right ventricular function in patients with ventricular tachycardia and normal left ventricular function.
abstract: We examined 40 patients with ventricular tachycardia (VT) and no evidence of heart disease, and found a 50% prevalence of ventricular late potentials (VLPs) on the signal-averaged electrocardiogram. This finding was associated with a significantly higher content of fibrous tissue on endomyocardial biopsy and a lower right ventricular ejection fraction. Thus, VLPs are frequently found in idiopathic VT, are a marker for subclinical anatomic and functional abnormalities of the right ventricle, and may be associated with a worse outcome.
authors.affiliation: Divisione di Cardiologia and Servizio di Anatomia Patologica, Ospedale S. Bortolo, Vicenza, Italy.
authors.forename: L
authors.initials: L
authors.lastname: La Vecchia
authors.forename: R
authors.initials: R
authors.lastname: Ometto
authors.forename: F
authors.initials: F
authors.lastname: Bedogni
authors.forename: G
authors.initials: G
authors.lastname: Finocchi
authors.forename: G M
authors.initials: GM
authors.lastname: Mosele
authors.forename: L
authors.initials: L
authors.lastname: Bozzola
authors.forename: P
authors.initials: P
authors.lastname: Bevilacqua
authors.forename: M
authors.initials: M
authors.lastname: Vincenzi
mesh_terms: D000328:Adult; D004562:Electrocardiography; D004719:Endomyocardial Fibrosis / Q000150:complications / Q000503:physiopathology*; D005260:Female; D006329:Heart Conduction System; D006801:Humans; D008297:Male; D008875:Middle Aged; D012815:Signal Processing, Computer-Assisted; D017180:Tachycardia, Ventricular / Q000150:complications / Q000503:physiopathology*; D016277:Ventricular Function, Left; D016278:Ventricular Function, Right