Fluorinated anesthetics differ in toxic effects on peritoneum and subjacent tissues.
Intraperitoneal injection of fluorinated anesthetics produced anesthesia in rats. This was followed by toxic effects on peritoneal organs and surfaces, except for sevoflurane, which did not produce any lesions.
Levine
S
S
Nathan S. Kline Institute for Psychiatric Research, Orangeburg, New York 10962, USA.
Saltzman
A
A
D000758:Anesthesia / Q000401:mortality; D018685:Anesthetics, Inhalation / Q000008:administration & dosage / Q000633:toxicity*; D000818:Animals; D005260:Female; D006221:Halothane / Q000008:administration & dosage / Q000633:toxicity*; D007274:Injections, Intraperitoneal; D007530:Isoflurane / Q000008:administration & dosage / Q000633:toxicity*; D008733:Methoxyflurane / Q000008:administration & dosage / Q000633:toxicity*; D008738:Methyl Ethers / Q000008:administration & dosage / Q000633:toxicity*; D010537:Peritoneum / Q000187:drug effects* / Q000473:pathology; D051381:Rats; D011917:Rats, Inbred Lew; D000077149:Sevoflurane; D013329:Structure-Activity Relationship
D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D008733:Methoxyflurane; D000077149:Sevoflurane; D007530:Isoflurane; D006221:Halothane