title: [The spontaneous variability of populations of fungal strains in the genus Aspergillus--producers of allergen-active substances].
abstract: The method of genetic selection has been used for obtaining the fungal cultures of Aspergillus strains, producers of allergen-active substances. The natural variability of populations of A. fumigatus, A. niger, A. clavatus strains as regards the intensity of conidia germination has been studied. These fungal species are the etiological agents of mycotic lesions of the body in cases of immunodeficiency. As the result of this study, 3 Aspergillus species, stable as regards the intensity of conidia germination, have been selected. The selected Aspergillus producer strains are successfully used for obtained allergen-active substances. The isolated allergen are used for the specific diagnostics of mold mycosis and mycogenic allergy.
authors.affiliation: Medical Academy of Post-Diploma Education, St. Petersburg, Russia.
authors.forename: N P
authors.initials: NP
authors.lastname: Zhuravleva
authors.forename: G A
authors.initials: GA
authors.lastname: Babenko
authors.forename: N N
authors.initials: NN
authors.lastname: Begaeva
mesh_terms: D000485:Allergens / Q000096:biosynthesis*; D001230:Aspergillus / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D001232:Aspergillus fumigatus / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity; D001234:Aspergillus niger / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity; D018070:Biological Specimen Banks; D014644:Genetic Variation; D006801:Humans; D012426:Russia; D012641:Selection, Genetic; D013172:Spores, Fungal
chemical_list: D000485:Allergens
vernacular_title: Spontannaia izmenchivost' populiatsiĭ shtammov gribov roda Aspergillus--produtsentov allergenoaktivnykh veshchestv.