MIRs are present in coding regions of human genes.
By using a weighted function and the method of enlarged similarity a search has been performed to identify mammalian interspersed repeats (MIRs) in DNA sequences from the EMBL data bank. The existence of MIRs is shown in coding regions of human genes and also in chicken and duck genomes. It is possible to conclude from the results obtained that MIRs were established in the coding regions of some genes and may have taken part in gene evolution. Furthermore, MIRs may have been amplified in vertebrate genomes before the origin of mammals.
Tulko
J S
JS
Bioengineering Center, Russian Academy of Sciences, Moscow, Russia.
Korotkov
E V
EV
Phoenix
D A
DA
D000465:Algorithms; D000818:Animals; D001483:Base Sequence; D001717:Birds / Q000235:genetics; D017124:Conserved Sequence; D004251:DNA Transposable Elements; D016208:Databases, Factual; D019143:Evolution, Molecular; D006801:Humans; D008322:Mammals / Q000235:genetics; D008957:Models, Genetic; D008969:Molecular Sequence Data; D012091:Repetitive Sequences, Nucleic Acid; D012689:Sequence Homology, Nucleic Acid
D004251:DNA Transposable Elements