Urethral prolapse after collagen injection.
A woman who was treated for intrinsic urethral sphincteric deficiency with periurethral injection of glutaraldehyde cross-linked collagen had prolapse of the urethral mucosa and recurrence of incontinence. She subsequently required surgical resection and a fascia lata sling. This is the first known occurrence of this postinjection complication.
Harris
R L
RL
Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina, USA.
Cundiff
G W
GW
Coates
K W
KW
Addison
W A
WA
Bump
R C
RC
D000368:Aged; D001672:Biocompatible Materials / Q000009:adverse effects*; D003094:Collagen / Q000009:adverse effects*; D003432:Cross-Linking Reagents / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007267:Injections; D011391:Prolapse; D019736:Prostheses and Implants / Q000009:adverse effects*; D012008:Recurrence; D014522:Urethral Diseases / Q000209:etiology* / Q000601:surgery; D014550:Urinary Incontinence, Stress / Q000628:therapy
D001672:Biocompatible Materials; D003432:Cross-Linking Reagents; C048470:glutaraldehyde-cross-linked collagen; D003094:Collagen