title: [Application from chemiluminescence to serological diagnosis of human toxoplasmosis].
abstract: Diagnostic Products Corporation has chosen chemiluminescent for the new kit of quantitative measurement of IgG and qualitative detection of IgM antibodies to Toxoplasma gondii, 878 human sera of principal diagnosis situations were tested, and the results obtained with the IMMULITE Toxoplasmosis kit were compared with those of the Parasitology and Mycology Laboratory of the University of Lille. Chemiluminescent allows a sensitive and specific determination of immunity. In the same ways, this method is able to detect earlier specific IgM and IgG during seroconversion. The kit of quantitative measurement of IgG and qualitative detection of IgM is reproducible and sensitive; this confirms the interest for the pediatric diagnosis of congenital toxoplasmosis.
authors.affiliation: Service de Parasitologie-Mycologie, Faculté de Médecine, Vandoeuvre-Les-Nancy, France.
authors.forename: B
authors.initials: B
authors.lastname: Fortier
authors.forename: A
authors.initials: A
authors.lastname: Dao
authors.forename: C
authors.initials: C
authors.lastname: Coignard-Chatain
authors.forename: M F
authors.initials: MF
authors.lastname: Biava
mesh_terms: D000368:Aged; D000818:Animals; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D007231:Infant, Newborn; D008163:Luminescent Measurements; D011247:Pregnancy; D015597:Pregnancy Complications, Parasitic / Q000175:diagnosis*; D014122:Toxoplasma / Q000276:immunology; D014123:Toxoplasmosis / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D014124:Toxoplasmosis, Animal; D014125:Toxoplasmosis, Congenital / Q000097:blood / Q000175:diagnosis
chemical_list: D007074:Immunoglobulin G; D007075:Immunoglobulin M
vernacular_title: Application de la chimiluminescence au diagnostic sérologique des toxoplasmoses humaines.