In vitro activities of quinupristin-dalfopristin and the streptogramin RPR 106972 against Mycoplasma pneumoniae.
The in vitro activities of quinupristin-dalfopristin and streptogramin RPR 106972 were determined with 44 strains of Mycoplasma pneumoniae and compared to those of macrolides, minocycline, and quinolones. All isolates tested were highly susceptible to macrolides and to quinupristin-dalfopristin (MIC at which 90% of the isolates are inhibited [MIC90], 0.0625 microg/ml), followed by RPR 106972 (MIC90, 0.5 microg/ml), quinolones, and minocycline.
Izumikawa
K
K
Department of Laboratory Medicine, Nagasaki University School of Medicine, Japan. peaton-ngs@umin.u-tokyo.ac.jp
Hirakata
Y
Y
Yamaguchi
T
T
Yoshida
R
R
Tanaka
H
H
Takemura
H
H
Maesaki
S
S
Tomono
K
K
Kaku
M
M
Izumikawa
K I
KI
Kamihira
S
S
Kohno
S
S
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests; D009177:Mycoplasma pneumoniae / Q000187:drug effects*; D014769:Virginiamycin / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; C099364:RPR 106972; D014769:Virginiamycin; C062940:quinupristin-dalfopristin