title: Clinically significant drug interactions in dermatology.
abstract: Access to information on clinically significant drug interactions is not readily available. This can be a source of uncertainty, and locating this information can be tedious and time-consuming. The pharmacology of drug interactions is briefly discussed. The most common drug interactions involve altered hepatic metabolism. At least 26 drugs are such frequent offenders that they can be considered "red flag" drugs. In addition, an extensive list of current significant and less significant drug interactions of particular importance to the dermatologist is presented.
authors.affiliation: Department of Dermatology, University of Oklahoma Health Sciences Center, Tulsa, USA.
authors.forename: V P
authors.initials: VP
authors.lastname: Barranco
mesh_terms: D003577:Cytochrome P-450 Enzyme System / Q000187:drug effects; D003879:Dermatologic Agents / Q000494:pharmacology*; D004347:Drug Interactions; D006801:Humans; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D012871:Skin Diseases / Q000188:drug therapy
chemical_list: D003879:Dermatologic Agents; D003577:Cytochrome P-450 Enzyme System