Efficacy of intravenous adenosine in treatment of paroxysmal supraventricular tachycardia in the local population.
In a prospective study conducted over 4 months at the Accident and Emergency Department, 21 patients with 24 episodes of spontaneous paroxysmal supraventricular tachycardia (PSVT) were treated with intravenous adenosine at incremental doses of 3 mg, 6 mg, 9 mg and 12 mg until termination of the PSVT. There were 6 males and 15 females. The mean age was 54 +/- 17 years (range from 23 to 83 years). The mean QRS rate was 171 +/- 21 per minute. When data were expressed in a cumulative manner, the response to intravenous adenosine 3 mg, 6 mg, 9 mg and 12 mg in the 24 episodes of PSVT were 5 episodes (21%), 16 episodes (67%), 20 episodes (83%) and 20 episodes (83%) respectively. Adverse effects were present in 10 episodes (42%) of the PSVT. They were all mild and transient, lasting less than 1 minute.
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Emergency Department National University Hospital, Singapore.
D000241:Adenosine / Q000008:administration & dosage*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013614:Tachycardia, Paroxysmal / Q000188:drug therapy*; D013617:Tachycardia, Supraventricular / Q000188:drug therapy*; D016896:Treatment Outcome
D000889:Anti-Arrhythmia Agents; D000241:Adenosine