title: [A novel use of cholinesterase amperometric biosensor for selective determination of 2,4-dichlorophenoxyacetic acid].
abstract: A new method of detection of 2,4-dichlorophenoxyacetic acid by means of immobilized monoclonal antibodies and an amperometric cholinesterase biosensor is proposed. A combination of monoclonal antibodies to 2,4-dichlorophenoxyacetic acid with an enzyme electrode provides high selectivity of measurements and allows trace amounts of this pesticide to be detected within a concentration range of 1 x 10(-1) to 5 x 10(-7) M with a sensitivity threshold of 5 x 10(-12) M.
authors.affiliation: Kazan State University, Tatarstan, Russia.
authors.forename: E P
authors.initials: EP
authors.lastname: Mediantseva
authors.forename: M G
authors.initials: MG
authors.lastname: Vertlib
authors.forename: G K
authors.initials: GK
authors.lastname: Budnikov
authors.forename: M P
authors.initials: MP
authors.lastname: Tyshlek
mesh_terms: D015084:2,4-Dichlorophenoxyacetic Acid / Q000032:analysis*; D000818:Animals; D015374:Biosensing Techniques; D002802:Cholinesterases; D004563:Electrochemistry; D004800:Enzymes, Immobilized; D005506:Food Contamination / Q000032:analysis; D006540:Herbicides / Q000032:analysis*; D008892:Milk / Q000737:chemistry; D012680:Sensitivity and Specificity
chemical_list: D004800:Enzymes, Immobilized; D006540:Herbicides; D015084:2,4-Dichlorophenoxyacetic Acid; D002802:Cholinesterases