Octreotide-induced bradycardia.
Because of deleterious hemodynamic effects of octreotide in a nonacromegalic patient with a pancreatic fistula, we conducted a MEDLINE search of English-language journal articles to extract information on this complication of octreotide or somatostatin therapy. Few data are available regarding patients with disease states other than acromegaly. We believe octreotide should be considered when determining the cause of bradycardia.
Herrington
A M
AM
Department of Pharmacy Services, Scott & White Memorial Hospital, Texas A&M University Health Science Center, Temple 76508, USA.
George
K W
KW
Moulds
C C
CC
D000328:Adult; D000743:Anemia, Hemolytic / Q000188:drug therapy; D018931:Antineoplastic Agents, Hormonal / Q000009:adverse effects* / Q000627:therapeutic use; D001919:Bradycardia / Q000139:chemically induced*; D002318:Cardiovascular Diseases / Q000139:chemically induced; D005260:Female; D006801:Humans; D015282:Octreotide / Q000009:adverse effects* / Q000627:therapeutic use
D018931:Antineoplastic Agents, Hormonal; D015282:Octreotide