[Concomitant manifestation of ochronosis and chronic polyarthritis in a patient].
Ochronosis is rare disorder of tyrosin catabolism with an autosomal, recessive trait. Clinical signs predominantly affect the locomotor system. Inflammatory episodes in large joints can mimick Rheumatoid Arthritis (RA). Brownish discoloration of sclerae and cartilage is characteristic, diagnosis is confirmed by typical changes of spinal X-rays and the findings of homogentisic acid in urine samples. We describe a case of a 53 year old female patient with ochronosis and a second diagnosis of RA.
Simianer
S
S
Klinik für Rheumatologie, Evangelisches Fachkrankenhaus, Ratingen.
Krause
D
D
Rau
R
R
D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D002869:Chromosome Aberrations / Q000235:genetics; D025063:Chromosome Disorders; D003937:Diagnosis, Differential; D005260:Female; D005808:Genes, Recessive; D006801:Humans; D008875:Middle Aged; D009794:Ochronosis / Q000150:complications* / Q000175:diagnosis / Q000235:genetics / Q000628:therapy; D012217:Rheumatoid Factor / Q000097:blood
D012217:Rheumatoid Factor