[Bulimia and autoimmunity].
In the first part of this study, we investigated the rate of natural autoantibodies, in a sample of 31 female inpatients with bulimia nervosa according to DSM III-R criteria. The control (age and sex matched) group consisted in high school students including 10 females without eating disorders, depressive disorder or immunological disease. We investigated especially natural autoantibodies reacting with compounds of the central nervous system (Dopamine, Dopamine beta Hydroxylase, Serotonin). Our first conclusion is that there is a lower level of these natural auto-antibodies among female patients with bulimia nervosa. In the second part of the study, we have especially investigated the correlation between impulsivity in bulimia nervosa and the rate of natural autoantibodies against serotonin.
Corcos
M
M
Institut Mutualiste Montsouris, Service de Psychiatrie de l'Adolescent et du Jeune Adulte du Pr Jeammet, Paris.
Atger
F Y
FY
Levy-Soussan
P
P
Avrameas
S
S
Guilbert
B
B
Jeammet
P
P
D000293:Adolescent; D000328:Adult; D001323:Autoantibodies / Q000097:blood*; D001327:Autoimmune Diseases / Q000276:immunology*; D001921:Brain / Q000276:immunology; D002032:Bulimia / Q000276:immunology*; D004298:Dopamine / Q000276:immunology; D005260:Female; D006801:Humans; D008297:Male; D018377:Neurotransmitter Agents / Q000276:immunology*; D012016:Reference Values; D012307:Risk Factors; D012701:Serotonin / Q000276:immunology
D001323:Autoantibodies; D018377:Neurotransmitter Agents; D012701:Serotonin; D004298:Dopamine