Potential effects of common drugs on stroke recovery.
Studies in laboratory animals clearly show that the rate and extent of functional recovery after focal brain injury can be modulated by drugs affecting certain neurotransmitters in the central nervous system. Preliminary clinical studies suggest that similar drug effects occur in humans recovering from stroke. Understanding these pharmacological effects is important because several of the classes of drugs that impair recovery in laboratory experiments are used to treat coincident medical problems in patients who have had a stroke.
Goldstein
L B
LB
Department of Medicine (Neurology) Veterans Affairs Medical Center and Center for Clinical Health Policy Research, Duke University, Durham, NC 27710, USA. golds004@mc.duke.edu
D000927:Anticonvulsants / Q000627:therapeutic use; D000928:Antidepressive Agents / Q000627:therapeutic use; D002561:Cerebrovascular Disorders / Q000188:drug therapy*; D015259:Dopamine Agents / Q000627:therapeutic use; D018682:GABA Agents / Q000627:therapeutic use; D006801:Humans; D018377:Neurotransmitter Agents / Q000627:therapeutic use; D011379:Prognosis; D016896:Treatment Outcome
D000927:Anticonvulsants; D000928:Antidepressive Agents; D015259:Dopamine Agents; D018682:GABA Agents; D018377:Neurotransmitter Agents