title: Quality of general movements in preterm infants with transient periventricular echodensities.
abstract: By means of sequential videotape recordings, the relevance of the quality of general movements for neurological outcome was determined in a group of 21 appropriate-for-gestational-age preterm infants with transient periventricular echodensities of variable localization and duration and in 6 infants without echodensities. Echodensities, especially in the parieto-occipital area, affected the quality of general movements. Echodensities persisting beyond 14d were associated with abnormal general movements; infants with echodensities up to 14 d had either normal or abnormal general movements. The developmental course of movement quality was correlated to neurological outcome (p < 0.005): normal outcomes were found in 11/12 infants with normal general movements throughout and in 9/11 infants with transient abnormal general movements; all 4 infants with persistent abnormal general movements had impaired outcomes. In infants with transient echodensities, longitudinal assessment of the quality of general movements helps to determine if there is brain dysfunction, either transient or persistent, and identifies infants at risk for impaired neurological outcomes.
authors.affiliation: Department of Paediatrics, Beatrix Children's Hospital, Groningen, The Netherlands.
authors.forename: A F
authors.initials: AF
authors.lastname: Bos
authors.forename: A
authors.initials: A
authors.lastname: Martijn
authors.forename: A
authors.initials: A
authors.lastname: Okken
authors.forename: H F
authors.initials: HF
authors.lastname: Prechtl
mesh_terms: D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000254:growth & development; D002657:Child Development / Q000502:physiology; D004453:Echoencephalography; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007969:Leukomalacia, Periventricular / Q000150:complications / Q000000981:diagnostic imaging*; D008297:Male; D009069:Movement Disorders / Q000000981:diagnostic imaging* / Q000209:etiology; D009460:Neurologic Examination; D011379:Prognosis; D012016:Reference Values; D012680:Sensitivity and Specificity