title: Self-assembling bis-dendritic peptides: design, synthesis and characterization of oxalyl-linked bis-glutamyl peptides [Glu(n)(CO2Me)n + 1-CO-]2; n = 1,3,7.
abstract: Three generations of glutamic acid dendrons [Glu(n),(CO2Me)n + 1; n = 1, 3, 7] have been joined together head-to-head by an oxalyl unit to form highly sterically congested bis-Glu-dendritic peptides with gelling properties. The single crystal X-ray structure of the first generation bis-dendritic peptide showed an extended hydrogen-bonded chiral tape with modest nonlinear optical activity.
authors.affiliation: Biomolecular Research Unit, Regional Research Laboratory (CSIR), Trivandrum, India.
authors.forename: D
authors.initials: D
authors.lastname: Ranganathan
authors.forename: S
authors.initials: S
authors.lastname: Kurur
authors.forename: K P
authors.initials: KP
authors.lastname: Madhusudanan
authors.forename: R
authors.initials: R
authors.lastname: Roy
authors.forename: I L
authors.initials: IL
authors.lastname: Karle
mesh_terms: D018360:Crystallography, X-Ray; D018698:Glutamic Acid / Q000737:chemistry*; D010455:Peptides / Q000138:chemical synthesis* / Q000737:chemistry*; D011487:Protein Conformation
chemical_list: D010455:Peptides; D018698:Glutamic Acid