title: Amebic osteomyelitis in a child with acquired immunodeficiency syndrome: a case report.
abstract: Disseminated Acanthamoeba infection has been described in immunocompromised or debilitated patients. The usual sites of involvement are skin, sinus, and brain. Sporadic reports of Acanthamoeba infection in patients infected with the human immunodeficiency virus are present in recent literature, predominantly in adults, and one case involving an 8-year-old child. We describe a case of amebic osteomyelitis, seen in a 6-year-old child with vertically acquired human immunodeficiency virus and a 6-month history of cutaneous Acanthamoeba infection.
authors.affiliation: Department of Pathology, Children's National Medical Center, Washington, DC 20010-2970, USA. dselby@cnmc.org
authors.forename: D M
authors.initials: DM
authors.lastname: Selby
authors.forename: R S
authors.initials: RS
authors.lastname: Chandra
authors.forename: T A
authors.initials: TA
authors.lastname: Rakusan
authors.forename: B
authors.initials: B
authors.lastname: Loechelt
authors.forename: B M
authors.initials: BM
authors.lastname: Markle
authors.forename: G S
authors.initials: GS
authors.lastname: Visvesvara
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D000048:Acanthamoeba; D000328:Adult; D000562:Amebiasis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D000818:Animals; D000977:Antiparasitic Agents; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001842:Bone and Bones / Q000473:pathology; D002648:Child; D005437:Flucytosine / Q000627:therapeutic use; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D010019:Osteomyelitis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D010419:Pentamidine / Q000627:therapeutic use; D012867:Skin / Q000473:pathology; D012876:Skin Diseases, Parasitic / Q000150:complications / Q000473:pathology
chemical_list: D000977:Antiparasitic Agents; D000981:Antiprotozoal Agents; D017964:Itraconazole; D010419:Pentamidine; D005437:Flucytosine