Maternal control of embryogenesis by MEDEA, a polycomb group gene in Arabidopsis.
The gametophytic maternal effect mutant medea (mea) shows aberrant growth regulation during embryogenesis in Arabidopsis thaliana. Embryos derived from mea eggs grow excessively and die during seed desiccation. Embryo lethality is independent of the paternal contribution and gene dosage. The mea phenotype is consistent with the parental conflict theory for the evolution of parent-of-origin-specific effects. MEA encodes a SET domain protein similar to Enhancer of zeste, a member of the Polycomb group. In animals, Polycomb group proteins ensure the stable inheritance of expression patterns through cell division and regulate the control of cell proliferation.
Grossniklaus
U
U
Cold Spring Harbor Laboratory, 1 Bungtown Road, Post Office Box 100, Cold Spring Harbor, NY 11724, USA. grossnik@cshl.org
Vielle-Calzada
J P
JP
Hoeppner
M A
MA
Gagliano
W B
WB
D000483:Alleles; D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000196:embryology* / Q000235:genetics*; D029681:Arabidopsis Proteins; D002455:Cell Division; D003001:Cloning, Molecular; D003433:Crosses, Genetic; D029721:Drosophila Proteins; D018628:Gene Dosage; D018506:Gene Expression Regulation, Plant; D017343:Genes, Plant; D019476:Insect Proteins / Q000235:genetics; D008969:Molecular Sequence Data; D009024:Morphogenesis; D009154:Mutation; D009687:Nuclear Proteins / Q000737:chemistry / Q000235:genetics; D010940:Plant Proteins / Q000737:chemistry / Q000235:genetics* / Q000502:physiology; D063150:Polycomb Repressive Complex 1; D063151:Polycomb Repressive Complex 2; D012097:Repressor Proteins; D012639:Seeds / Q000235:genetics / Q000254:growth & development; D016415:Sequence Alignment
D029681:Arabidopsis Proteins; D029721:Drosophila Proteins; D019476:Insect Proteins; C111712:MEA protein, Arabidopsis; D009687:Nuclear Proteins; C066770:Pc protein, Drosophila; D010940:Plant Proteins; D012097:Repressor Proteins; C083329:E(z) protein, Drosophila; D063151:Polycomb Repressive Complex 2; D063150:Polycomb Repressive Complex 1