Parental history of hypertension and hostility moderate cardiovascular responses to interpersonal conflict.
A parental history of hypertension has been implicated in the development of hypertension, perhaps by virtue of an elevated cardiovascular response to stress. Similarly, hostility has been hypothesized to be linked to cardiovascular disease through cardiovascular hyperreactivity. The interaction of parental history and hostility in moderating cardiovascular response has been infrequently examined, though research suggests the two may be linked through familial factors. The present study examined the cardiovascular response of 98 healthy young adult males categorized as offspring of hypertensive subjects (PH+) or offspring of normotensive subjects (PH-) and as high or low hostile, based on Cook-Medley Hostility scores (HiHo vs. LoHo). Subjects were exposed to either an harassment or non-harassment stressor. Results indicated elevated cardiac output and forearm blood flow responses in PH+/HiHo subjects who were harassed as compared to any other harassed subject and all non-harassed individuals. This hemodynamic response pattern of elevated blood flow suggests a mechanism of hypertensive disease development.
Miller
S B
SB
Department of Psychology, Concordia University, Montreal, Quebec, Canada.
Dolgoy
L
L
Friese
M
M
Sita
A
A
D000328:Adult; D000786:Anger / Q000502:physiology; D001007:Anxiety / Q000503:physiopathology / Q000523:psychology; D001794:Blood Pressure / Q000502:physiology; D003220:Conflict, Psychological; D006439:Hemodynamics / Q000502:physiology*; D006791:Hostility; D006801:Humans; D006973:Hypertension / Q000235:genetics / Q000503:physiopathology* / Q000523:psychology; D008297:Male; D010556:Personality Tests; D013315:Stress, Psychological / Q000503:physiopathology / Q000523:psychology