title: Malignant glioma. Evaluation with 3D time-of-flight MR angiography.
abstract: OBJECTIVE
  To investigate the clinical utility of 3D time-of-flight (TOF) MR angiography (MRA) in the evaluation of pathological vessels in patients with malignant glioma.
  
  
  METHODS
  Sixteen patients with malignant glioma (12 with glioblastoma multiforme and 4 with anaplastic astrocytoma) were examined with 3D TOF MRA before and after the injection of gadopentetate dimeglumine. The 3D TOF MRA study was compared with conventional angiography in all patients.
  
  
  RESULTS
  The unenhanced 3D TOF MRAs successfully depicted the feeding arteries in 9 patients but failed to depict small feeding arteries in 2 patients in whom these arteries were shown by conventional angiography. The enhanced MRAs demonstrated draining veins from the lesions in 8 patients but failed to depict a draining vein in 1 patient that was shown by conventional angiography. The stereoscopic view projection effectively depicted displacements of the major cerebral arteries in 14 patients, and deep venous structures in 11 patients which almost accorded with the findings at conventional angiography.
  
  
  CONCLUSIONS
  Our results indicate that 3D TOF MRA can provide an accurate visualization of pathological vascular structures and thus help establish a diagnosis in patients with malignant glioma.
authors.affiliation: Department of Diagnostic Radiology, Osaka Medical Center for Cancer and Cardiovascular Diseases, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Kadota
authors.forename: H
authors.initials: H
authors.lastname: Nakagawa
authors.forename: C
authors.initials: C
authors.lastname: Kuroda
mesh_terms: D000328:Adult; D000368:Aged; D000792:Angiography; D005069:Evaluation Studies as Topic; D005260:Female; D019786:Gadolinium DTPA; D005910:Glioma / Q000175:diagnosis* / Q000000981:diagnostic imaging; D006801:Humans; D007091:Image Processing, Computer-Assisted; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged
chemical_list: D019786:Gadolinium DTPA