title: [Consequences of a bipolar disorder and use of mood stabilizers for its management during pregnancy].
abstract: For patients with a bipolar disorder who are pregnant or consider pregnancy, the following issues are of importance: Genetic counselling: genetic vulnerability is virtually certainly the basis of the occurrence of a bipolar disorder.
  
  
  METHODS
  discontinuation of the medication may lead to recurrence; continuation may cause intoxications in the woman and her child and congenital anomalies in the child. Alternatives to mood stabilizers can be applied; electroconvulsive therapy is a possibility as is medication with antidepressants, antipsychotics and benzodiazepines during acute episodes of mood disorder. Precautions for mother and child if mood-stabilizing treatment is continued: use sustained-release preparations, regularly check blood levels and thyroid function, administer vitamin K if necessary, perform ultrasonoscopy/examination of amniotic fluid, have the child delivered in hospital. Management of the newborn child: observation, determination of blood levels, regular checks of thyroid function, if necessary administration of vitamin K.
authors.affiliation: Psychiatrisch Ziekenhuis Endegeest, Jelgersmapolikliniek, Oegstgeest.
authors.forename: E A
authors.initials: EA
authors.lastname: Knoppert-van der Klein
authors.forename: P
authors.initials: P
authors.lastname: Kölling
authors.forename: E M
authors.initials: EM
authors.lastname: van Gent
authors.forename: I L
authors.initials: IL
authors.lastname: van Kamp
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000209:etiology; D000328:Adult; D001714:Bipolar Disorder / Q000188:drug therapy* / Q000235:genetics / Q000628:therapy; D004565:Electroconvulsive Therapy; D005260:Female; D005817:Genetic Counseling; D006801:Humans; D007231:Infant, Newborn; D011181:Postnatal Care; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*; D011295:Prenatal Care; D011619:Psychotropic Drugs / Q000009:adverse effects / Q000627:therapeutic use*; D018570:Risk Assessment
chemical_list: D011619:Psychotropic Drugs