[The results of a morphological study of the gastric and duodenal mucosae in patients with vibration-induced disease].
OBJECTIVE
Morphological study of gastric and duodenal mucosa in patients with vibration disease.


METHODS
64 patients with vibration disease stage I and II were examined endoscopically, histologically, bacterioscopically and morphometrically irrespective of the presence or absence of gastrointestinal complaints.


RESULTS
Erosive gastroduodenitis, non-erosive gastroduodenitis and gastritis, polyps in the stomach and gastric ulcer were diagnosed in 19(29.7%), 40(62.5%), 2(3.2%) and 1(1.6%) patients, respectively. Small intestinal metaplasia occurred in 22% of patients. Helicobacter pylori occurred most frequently in the antral part of the stomach (90.24%). Advanced dissemination often combined with metaplasia of the small bowel. Morphometrically, there were slight differences from relevant values in patients with chronic gastroduodenitis who were not exposed to occupational hazards. Vibration disease patients exhibited impairment of duodenal vessels (large endothelial nuclei, thick arteriolar walls) 2 times more frequently than controls.


CONCLUSIONS
In vibration disease, gastric and duodenal mucosa, as a rule, shows signs of chronic gastroduodenitis.
Liubchenko
P N
PN
Novikova
A V
AV
Karpov
V N
VN
Gorenkov
R V
RV
Tereshchenko
S G
SG
Dement'eva
O Iu
OIu
D000328:Adult; D001706:Biopsy; D004382:Duodenitis / Q000209:etiology / Q000473:pathology; D004386:Duodenum / Q000473:pathology*; D016099:Endoscopy, Gastrointestinal; D005753:Gastric Mucosa / Q000473:pathology*; D005756:Gastritis / Q000209:etiology / Q000473:pathology; D016481:Helicobacter Infections / Q000209:etiology / Q000473:pathology; D016480:Helicobacter pylori; D006801:Humans; D007413:Intestinal Mucosa / Q000473:pathology*; D008875:Middle Aged; D009784:Occupational Diseases / Q000209:etiology / Q000473:pathology*; D014732:Vibration / Q000009:adverse effects*