Weak inhibitors of cyclooxygenases may exert their antinociceptive effect by modulation of transcription factors.
Scheuren
N
N
Institute of Experimental and Clinical Pharmacology and Toxicology, University of Erlangen-Nürnberg, Germany.
Bang
H
H
Münster
T
T
Brune
K
K
Pahl
A
A
D000700:Analgesics / Q000494:pharmacology*; D001665:Binding Sites; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology*; D006801:Humans; D007052:Ibuprofen / Q000494:pharmacology*; D019169:Jurkat Cells; D007700:Kinetics; D016328:NF-kappa B / Q000378:metabolism*; D013237:Stereoisomerism; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D014157:Transcription Factors / Q000378:metabolism*
D000700:Analgesics; D016861:Cyclooxygenase Inhibitors; D016328:NF-kappa B; D014157:Transcription Factors; D013755:Tetradecanoylphorbol Acetate; D007052:Ibuprofen