title: Developmental signalling: a careful balancing act.
abstract: Embryos of arthropods and chordates are patterned along the dorso-ventral axis by a gradient of secreted morphogens of the Bmp4/Dpp family. This gradient now appears to be shaped by the opposing activities of Bmp-sequestering proteins, on the one hand, and Bmp-releasing metalloproteases, on the other.
authors.affiliation: LGPD, Institut de Biologie du Développement de Marseille, CNRS/INSERM/Université de la Méditerranée/AP de Marseille, Campus de Luminy, Case 907, F-13288, Marseille, France. lemaire@lgpd.univ-mrs.fr
authors.forename: P
authors.initials: P
authors.lastname: Lemaire
authors.forename: H
authors.initials: H
authors.lastname: Yasuo
mesh_terms: D000818:Animals; D001181:Arthropods / Q000196:embryology* / Q000235:genetics / Q000378:metabolism; D019521:Body Patterning; D019485:Bone Morphogenetic Proteins / Q000235:genetics / Q000378:metabolism; D002816:Chordata, Nonvertebrate / Q000196:embryology* / Q000235:genetics / Q000378:metabolism; D008954:Models, Biological; D015398:Signal Transduction
chemical_list: D019485:Bone Morphogenetic Proteins