An unusual case of primary systemic amyloidosis.
Here we report an unusual case of primary systemic amyloidosis. The cutaneous lesions were polymorphic and included involvement of both external auditory canals. The visceral involvement was covert. Mapping of amyloid deposits was performed using scintigraphy with technetium-99m (V) dimercaptosuccinic acid ([99mTc (V)] DMSA). Therapy with melphalan, prednisone and colchicine resulted in considerable improvement.
Ambrosone
L
L
Istituto di Clinica Medica-Reumatologia, Seconda Università di Napoli, Italy.
Mansi
L
L
Salvatore
T
T
Marino
F
F
Orabona
P
P
Rambaldi
A
A
Rambaldi
P F
PF
Rambaldi
M
M
D000368:Aged; D000686:Amyloidosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use; D003078:Colchicine / Q000627:therapeutic use; D005260:Female; D006074:Gout Suppressants / Q000627:therapeutic use; D006801:Humans; D008558:Melphalan / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D011877:Radionuclide Imaging; D012871:Skin Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D019783:Technetium Tc 99m Dimercaptosuccinic Acid
D000893:Anti-Inflammatory Agents; D018906:Antineoplastic Agents, Alkylating; D006074:Gout Suppressants; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D008558:Melphalan; D003078:Colchicine; D011241:Prednisone