[Coccidioidomycosis as the cause of granulomatous hepatitis].
The case of 36-year-old man is reported who fell ill with a febrile infection, shortly after returning from several weeks to Mexico.


RESULTS
Chest X-ray revealed a pulmonary infiltration. Also, the levels of liver function tests (gamma-GT, alkaline phosphatase, SGOT, SGPT) were clearly increased. As there were no signs of extended bile ducts in ultrasonics, a liver biopsy was indicated. The histology showed a granulomatous hepatitis.


METHODS
The exposure during the Mexico-trip, the pulmonary infiltration, the histology and the significant raised titers in specific serological tests led to the diagnosis of a general infection by the fungus coccidioides immitis. In addition to pathogenetic aspects of coccidioidomycosis the diagnostic approaches and relevant therapeutic strategies are discussed.
Zangerl
B
B
II. Medizinische Klinik, St.-Franziskus-Hospitals Münster.
Edel
G
G
von Manitius
J
J
Schmidt-Wilcke
H A
HA
D000328:Adult; D001706:Biopsy; D003047:Coccidioidomycosis / Q000175:diagnosis* / Q000473:pathology; D006099:Granuloma / Q000175:diagnosis* / Q000473:pathology; D006505:Hepatitis / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008099:Liver / Q000473:pathology; D008111:Liver Function Tests; D008172:Lung Diseases, Fungal / Q000175:diagnosis / Q000473:pathology; D008297:Male