Contemporaneous acute myeloid leukaemia and sarcoidosis. Report of three cases.
Three cases of contemporaneous acute myeloid leukaemia (AML) and sarcoidosis are described. The possible pathogenic mechanisms concerning their concurrent appearance are discussed: if sarcoidosis impaired T-cell response, it could perhaps predispose the development of AML; alternatively, the development of sarcoidosis during AML may be due to a reaction linked to a diffuse release of tumour antigens with a subsequent formation of a non-caseating granulomata.
Pagano
L
L
Institute of Semeiotica Medica, Catholic University, Roma, Italy.
Visani
G
G
Ferrara
F
F
Cenacchi
A
A
Bonini
A
A
Equitani
F
F
Fuso
L
L
Piscitelli
R
R
Pagliari
G
G
D000208:Acute Disease; D000328:Adult; D005260:Female; D006801:Humans; D007951:Leukemia, Myeloid / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D017565:Sarcoidosis, Pulmonary / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology; D013601:T-Lymphocytes / Q000276:immunology