title: Histopathological study of the effect of phacoemulsification-aspiration on iris muscles.
abstract: Phacoemulsification-aspiration (PEA) followed by peripheral iridectomy was performed in 10 patients, and the dissected iris fragments were examined by electron microscopy. Organic changes such as cytoplasmic vacuolation and lamellar formation were observed in both the sphincter and dilator muscles of the pupil. No changes in the axons were detected. The same findings were observed when a simian eye was examined after PEA. These results indicate that PEA causes injury to iris muscles.
authors.affiliation: Department of Ophthalmology, Musashino Red Cross Hospital, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Komatsu
authors.forename: S
authors.initials: S
authors.lastname: Uga
authors.forename: S
authors.initials: S
authors.lastname: Oono
authors.forename: K
authors.initials: K
authors.lastname: Shimizu
authors.forename: M
authors.initials: M
authors.lastname: Kohara
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D001369:Axons / Q000648:ultrastructure; D001485:Basement Membrane / Q000648:ultrastructure; D004322:Drainage; D005260:Female; D006801:Humans; D007431:Intraoperative Complications / Q000473:pathology*; D007498:Iris / Q000293:injuries* / Q000601:surgery / Q000648:ultrastructure; D008251:Macaca; D008297:Male; D008875:Middle Aged; D009130:Muscle, Smooth / Q000293:injuries* / Q000601:surgery / Q000648:ultrastructure; D018918:Phacoemulsification / Q000009:adverse effects*; D014617:Vacuoles / Q000648:ultrastructure