title: Carcinoma of the male breast metastatic to both orbits.
abstract: We report the case of a 43-year-old man who presented with painless proptosis of the right eye of 6 weeks' duration. Examination demonstrated a tense right orbit and decreased vision and extraocular motility bilaterally. Diagnostic evaluation included computed tomographic imaging of the head and orbits, a therapeutic trial of high-dose systemic corticosteroids, and orbital biopsy, which revealed the presence of metastatic adenocarcinoma. The primary tumor was found to be an estrogen-receptor-positive, infiltrating ductal adenocarcinoma of the right breast. Therapy included lumpectomy of the breast mass, orbital irradiation, and hormonal therapy. Metastatic carcinoma of the breast should be considered in the differential diagnosis of orbital neoplastic disease in the male patient.
authors.affiliation: Department of Ophthalmology, Jules Stein Eye Institute, University of California, Los Angeles School of Medicine 90024, USA.
authors.forename: G H
authors.initials: GH
authors.lastname: Garcia
authors.forename: D A
authors.initials: DA
authors.lastname: Weinberg
authors.forename: B J
authors.initials: BJ
authors.lastname: Glasgow
authors.forename: K E
authors.initials: KE
authors.lastname: Hunt
authors.forename: R
authors.initials: R
authors.lastname: Venegas
authors.forename: R A
authors.initials: RA
authors.lastname: Goldberg
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D018567:Breast Neoplasms, Male / Q000378:metabolism / Q000473:pathology* / Q000628:therapy; D018270:Carcinoma, Ductal, Breast / Q000378:metabolism / Q000556:secondary* / Q000628:therapy; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D015412:Mastectomy, Segmental; D009915:Orbit / Q000000981:diagnostic imaging; D009918:Orbital Neoplasms / Q000378:metabolism / Q000556:secondary* / Q000628:therapy; D011960:Receptors, Estrogen / Q000378:metabolism; D014057:Tomography, X-Ray Computed
chemical_list: D011960:Receptors, Estrogen