Isolation of a new member of DnaJ-like heat shock protein 40 (Hsp40) from human liver.
A new member of Hsp40, HLJ1, consisting of 337 amino acids, was cloned from a human liver cDNA library. The deduced amino acid sequence of HLJ1 has an 84% homology (69% identity) with that of HDJ-1 isolated from human placenta. Northern analysis showed that expression of the HLJ1 gene is heat-inducible and its transcription shows some degree of preference in heart, skeletal muscle, and pancreas.
Hoe
K L
KL
Cell Cycle and Signal Research Unit, Korea Research Institute of Bioscience and Biotechnology, Taejon, South Korea.
Won
M
M
Chung
K S
KS
Jang
Y J
YJ
Lee
S B
SB
Kim
D U
DU
Lee
J W
JW
Yun
J H
JH
Yoo
H S
HS
D000595:Amino Acid Sequence; D001483:Base Sequence; D003001:Cloning, Molecular; D015723:Gene Library; D050956:HSP40 Heat-Shock Proteins; D006360:Heat-Shock Proteins / Q000302:isolation & purification*; D006801:Humans; D008099:Liver / Q000737:chemistry*; D008969:Molecular Sequence Data; D010920:Placenta / Q000737:chemistry; D017386:Sequence Homology, Amino Acid
C494647:DNAJB1 protein, human; C494650:DNAJB4 protein, human; D050956:HSP40 Heat-Shock Proteins; D006360:Heat-Shock Proteins