Optical chemical imaging of tobacco mosaic virus in solution at 60-nm resolution.
Scanning near-field optical microscopy can provide images with a resolution less than the wavelength of light, and therefore ought in principle to be of great value in studies of biological structures. In this work we show how for the first time images have been obtained of tobacco mosaic virus particles at 60-nm resolution, combined with chemical imaging using monoclonal antibodies under in vitro conditions.
Keller
T H
TH
Department of Chemistry, University of Cambridge, England.
Rayment
T
T
Klenerman
D
D
D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D055592:Biophysical Phenomena; D001703:Biophysics; D008853:Microscopy / Q000379:methods; D018625:Microscopy, Atomic Force; D055095:Optics and Photonics; D012996:Solutions; D014027:Tobacco Mosaic Virus / Q000737:chemistry* / Q000276:immunology / Q000648:ultrastructure*
D000911:Antibodies, Monoclonal; D000914:Antibodies, Viral; D012996:Solutions