title: Conservative management of splenic rupture in a haemophiliac adult.
abstract: The recognition of the grave risk of overwhelming sepsis in splenectomized individuals has led to the search for alternatives to splenectomy. Conservative management, first tried successfully in children and later extended to adult patients, has become the accepted form of treatment and has also been tried with success in haemophiliac children. The case presented here is important because this is the first report of a successful outcome of non-operative treatment of a ruptured spleen in a haemophiliac adult.
authors.affiliation: Department of Surgery, Torbay Hospital, Devon, UK.
authors.forename: K
authors.initials: K
authors.lastname: Nigam
authors.forename: R G
authors.initials: RG
authors.lastname: Hughes
authors.forename: B
authors.initials: B
authors.lastname: Murphy
mesh_terms: D000328:Adult; D005169:Factor VIII / Q000627:therapeutic use; D006467:Hemophilia A / Q000150:complications*; D006801:Humans; D008297:Male; D012422:Rupture, Spontaneous; D013161:Splenic Rupture / Q000209:etiology / Q000628:therapy*
chemical_list: D005169:Factor VIII