Pyrrolidinoindoline Alkaloids from Psychotria colorata1
Fractionation of an alkaloid extract of Psychotria colorata flowers led to the isolation of six alkaloids, identified by UV, 1D and 2D NMR, and MS as (-)-calycanthine, isocalycanthine, (+)-chimonanthine, hodgkinsine, quadrigemine C, and a new alkaloid (1), whose structure was deduced by X-ray analysis to be (8-8a),(8'-8'a)-tetradehydroisocalycanthine 3a(R), 3'a(R).
Verotta
L
Dipartimento di Chimica Organica e Industriale, Università degli Studi, via Venezian 21, 20133 Milano, Italy, Centro per lo Studio delle Relazioni tra Struttura e Reattività Chimica del CNR, via Golgi 19, 20133 Milano, Italy, Structure Based Drug Design, Pharmacia & Upjohn, via Pasteur 10, 20014 Nerviano (MI), Italy, Departamento de Farmacologia, Universidade Federal do Rio Grande do Sul, CP 5072, Porto Alegre (RS), Brazil, and Curso de Pós-Graduação en Química, Universidade Federal do Parà, Belém (PA), Brazil.
Pilati
T
Tatò
M
Elisabetsky
E
Amador
TA
Nunes
DS