Analysis of postoperative vaginal vault radiotherapy of stage I endometrial cancer with different radionuclides.
A total of 213 patients in stage I grade 1 endometrial cancer were treated postoperatively with either radium or caesium vaginal applicators. The rate of complication and the incidence of second malignancies were studied in both groups. The frequency of grades 2 and 3 vaginal complications was higher among patients treated with caesium applicators but not statistically significant. The observed number of second malignancies was significantly higher than expected in the radium-treated group, in which the observed number of second malignancies with distant location was also significantly higher than expected, which could not be found in the caesium group.
Ryberg
M
M
Department of Gynecological Oncology, Radiumhemmet, Karolinska Hospital, Stockholm, Sweden.
Hamed
A F
AF
Nilsson
B
B
Rudén
B I
BI
Einhorn
N
N
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001918:Brachytherapy / Q000009:adverse effects; D002588:Cesium Radioisotopes / Q000009:adverse effects / Q000627:therapeutic use*; D016889:Endometrial Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology; D016609:Neoplasms, Second Primary / Q000453:epidemiology; D011182:Postoperative Care; D019275:Radiopharmaceuticals / Q000009:adverse effects / Q000627:therapeutic use*; D011883:Radium / Q000009:adverse effects / Q000627:therapeutic use*; D016019:Survival Analysis
D002588:Cesium Radioisotopes; D019275:Radiopharmaceuticals; D011883:Radium