title: ERIC-PCR typing profiles of Enterobacter cloacae are stable after development of advanced cephalosporin resistance.
abstract: Enterobacterial repetitive intergenic consensus (ERIC) sequence polymerase chain reaction genotype profiles of Enterobacter cloacae were prepared for paired isolates which were obtained before and after the high level expression of the chromosomal cephalosporinase. These profiles were homologous within strain pairs which suggests that the acquired resistance does not lead to major chromosomal alterations. ERIC genotypes are therefore reliable markers in epidemiological investigations where antibiogram modifications may arise as a consequence of antibiotic exposure and beta-lactamase over-production..
authors.affiliation: Program of Microbiology, Virology and Infection Control, British Columbia's Children's Hospital, Vancouver, Canada.
authors.forename: A
authors.initials: A
authors.lastname: Zaher
authors.forename: N
authors.initials: N
authors.lastname: Cimolai
mesh_terms: D015373:Bacterial Typing Techniques; D018550:Cephalosporin Resistance / Q000235:genetics*; D016384:Consensus Sequence; D016172:DNA Fingerprinting; D004587:Electrophoresis, Agar Gel; D016972:Enterobacter cloacae / Q000145:classification* / Q000187:drug effects / Q000235:genetics*; D004813:Epidemiology; D006801:Humans; D016133:Polymerase Chain Reaction