title: A computer model of intracranial dynamics integrated to a full-scale patient simulator.
abstract: The ability to visualize intracranial dynamics during simulated clinical scenarios is a valuable tool for teaching brain physiology and the consequences of different medical interventions on the brain. Studies have isolated physiologic variables and shown their effects on brain dynamics. However, no studies have shown the combined effects of these variables on intracranial dynamics. This brain model offers one approach that brings all these relationships together and shows how they affect the dynamics of the brain. The brain model obtains its physiologic inputs from a full-scale patient simulator which responds to clinical interventions. This integration allows individuals working on the patient simulator to see the effects of their actions on brain dynamics. The brain model gives a real-time display of intracranial events (cerebral metabolic rate, cerebral blood flow, cerebral blood volume, cerebral perfusion pressure, and intracranial pressure) and responds to changes in the pulmonary and cardiovascular condition of the patient simulator.
authors.affiliation: Department of Anesthesiology, University of Florida Brain Institute, University of Florida College of Medicine, Gainesville 32608, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Thoman
authors.forename: S
authors.initials: S
authors.lastname: Lampotang
authors.forename: D
authors.initials: D
authors.lastname: Gravenstein
authors.forename: J
authors.initials: J
authors.lastname: van der Aa
mesh_terms: D001810:Blood Volume; D001921:Brain / Q000502:physiology*; D001930:Brain Injuries / Q000503:physiopathology; D002560:Cerebrovascular Circulation; D003198:Computer Simulation; D006801:Humans; D007427:Intracranial Pressure; D008959:Models, Neurological; D010313:Partial Pressure; D005791:Patient Care; D010477:Perfusion