title: Primary epithelioid hemangioendothelioma of the clivus.
abstract: We describe the clinical, radiologic, and pathologic features of a primary intracranial hemangioendothelioma arising in the clivus in a 38-year-old female, emphasizing the importance of including this rare entity in the differential diagnosis of tumors arising at the base of the skull. To our knowledge, this is the first reported case of a clival hemangioendothelioma. Aside from its unusual location, this case is also notable for its apparent rapid growth and mixed epithelioid-spindle cell morphology. Appropriate neuroimaging studies may offer crucial information, ensuring that this uncommon entity is included in the differential diagnosis of a clival mass.
authors.affiliation: Department of Pathology, University of Texas Southwestern Medical Center at Dallas 75235-9072, USA.
authors.forename: E J
authors.initials: EJ
authors.lastname: Rushing
authors.forename: J A
authors.initials: JA
authors.lastname: White
authors.forename: M D
authors.initials: MD
authors.lastname: D' Alise
authors.forename: D P
authors.initials: DP
authors.lastname: Chason
authors.forename: C L
authors.initials: CL
authors.lastname: White
authors.forename: E H
authors.initials: EH
authors.lastname: Bigio
mesh_terms: D000199:Actins / Q000032:analysis; D000328:Adult; D000792:Angiography; D003388:Cranial Fossa, Posterior; D005260:Female; D018323:Hemangioendothelioma, Epithelioid / Q000737:chemistry / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D019394:Ki-67 Antigen / Q000032:analysis; D008279:Magnetic Resonance Imaging; D019292:Skull Base Neoplasms / Q000737:chemistry / Q000473:pathology*
chemical_list: D000199:Actins; D019394:Ki-67 Antigen