title: [A case of multifocal Langerhans cell granulomatosis: a BAL follow up study].
abstract: Langerhans cell granulomatosis, once called histiocytosis X, is a rare disease. A case of multifocal Langerhans cell granulomatosis in the bone, lymph nodes, skin and lungs of an 18-year-old man is described. Head CT and MRI showed a soft tissue mass of the left temporal bone. Lymph node and skin biopsies substantiated a diagnosis of Langerhans cell granulomatosis. A High resolution CT scan of the lung revealed a small cystic lesion, and bronchoalveolar lavage (BAL) showed an increased number of S-100 positive cells. Steroid therapy resulted in complete resolution, and no S-100 positive cells were obtained in the follow-up BAL study.
authors.affiliation: Department of Respiratory Medicine, Nishi-Kobe Medical Center, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Tomioka
authors.forename: R
authors.initials: R
authors.lastname: Fujiyama
authors.forename: H
authors.initials: H
authors.lastname: Ohnishi
authors.forename: T
authors.initials: T
authors.lastname: Sakurai
authors.forename: K
authors.initials: K
authors.lastname: Tada
authors.forename: H
authors.initials: H
authors.lastname: Sakamoto
authors.forename: H
authors.initials: H
authors.lastname: Iwasaki
authors.forename: K
authors.initials: K
authors.lastname: Imanaka
authors.forename: K
authors.initials: K
authors.lastname: Hashimoto
mesh_terms: D000293:Adolescent; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology* / Q000276:immunology; D005500:Follow-Up Studies; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008297:Male