Signaling angiogenesis and lymphangiogenesis.
Exciting progress has been made in elucidating the complex network of receptor-ligand interactions that regulate blood vessel growth. Understanding these control mechanisms is of interest not only because of their role in developmental biology, but because they provide potential therapeutic strategies for disease processes involving angiogenesis, such as tumor growth.
Korpelainen
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EI
Molecular/Cancer Biology Laboratory, Haartman Institute, University of Helsinki, Finland.
Alitalo
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K
D000818:Animals; D004729:Endothelium, Lymphatic / Q000196:embryology / Q000502:physiology* / Q000503:physiopathology; D006801:Humans; D008954:Models, Biological; D018919:Neovascularization, Physiologic / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*