[Did glucan in indoor environment cause respiratory tract inflammation?].
Three children living in a house affected by mould manifested severe airways and general symptoms indicative of non-specific airways inflammation. Measurement of airborne (1-->3)-beta-D-glucan, a cell wall constituent in moulds, yielded values ranging from 22 to 115 ng/m3, as compared to normal values of some few ng/m3. On moving to relatives, all three children improved and could terminate medication after 2-3 weeks. The findings are consistent with previous reports of symptoms induced by exposure to mould, and suggest that quantification of viable organisms may not adequately reflect the exposure risk.
Rylander
R
R
Göteborgs universitet.
Fogelmark
B
B
Danielsson
B
B
D000328:Adult; D016902:Air Pollution, Indoor / Q000009:adverse effects; D002675:Child, Preschool; D005260:Female; D005936:Glucans / Q000009:adverse effects* / Q000032:analysis; D006801:Humans; D006813:Humidity; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D012140:Respiratory Tract Diseases / Q000139:chemically induced*; D018877:Sick Building Syndrome / Q000139:chemically induced*; D013172:Spores, Fungal
D005936:Glucans