Propionibacterium acnes colonization in acne and nonacne.
Propionibacterium acnes is a number of the resident bacterial flora and resides in sebaceous follicles. Age-related and body-dependent quantitative differences exist, indicating the role of sebum as an important ecological factor for P. acnes. Acne patients demonstrate marked increases in this organism which generates inflammation through a variety of mechanisms.
Leyden
J J
JJ
University of Pennsylvania Hospital, Philadelphia 19104, USA.
McGinley
K J
KJ
Vowels
B
B
D000152:Acne Vulgaris / Q000382:microbiology*; D000293:Adolescent; D000367:Age Factors; D002648:Child; D006801:Humans; D007223:Infant; D011425:Propionibacterium acnes / Q000302:isolation & purification*; D012627:Sebaceous Glands / Q000382:microbiology; D012867:Skin / Q000382:microbiology*