Characterization of a malignant eccrine poroma by cytogenetic and fluorescence in situ hybridization techniques.
We have cytogenetically and by fluorescence in situ hybridization (FISH) analyzed short-term cultures from a malignant eccrine poroma, a type of tumor in which chromosomal abnormalities have previously not been reported. Combining the results from G-banding and FISH, the karyotype was interpreted as 50,XX,t(3;11;12)(q21;p15;q15),+5,+7,+9, +9,t(12;22)(q13;q13),+del(12)(q15),der(15)t(3;15) (q23;p13),der(17)t(8;17)(q22;p13),-20,add(22)(q13).
Jin
Y
Y
Department of Clinical Genetics, University Hospital, Lund, Sweden.
Jin
C
C
Mertens
F
F
Persson
B
B
Jonsson
N
N
D018250:Acrospiroma / Q000235:genetics* / Q000473:pathology; D000368:Aged; D002869:Chromosome Aberrations; D002871:Chromosome Banding; D005260:Female; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D007621:Karyotyping; D013544:Sweat Gland Neoplasms / Q000235:genetics* / Q000473:pathology