Activation of 5-lipoxygenase in whole polymorphonuclear leukocytes by arachidonic acid: evidence of cytosolic active enzyme.
Vila
L
L
Inflammation and Cell Proliferation Mediators Lab, Santa Creu i Sant Pau Hospital, Barcelona, Spain.
Sola
J
J
D001094:Arachidonate 5-Lipoxygenase / Q000097:blood* / Q000187:drug effects; D016718:Arachidonic Acid / Q000097:blood / Q000378:metabolism* / Q000494:pharmacology*; D002118:Calcium / Q000097:blood; D002851:Chromatography, High Pressure Liquid; D003600:Cytosol / Q000201:enzymology / Q000378:metabolism; D015777:Eicosanoids / Q000096:biosynthesis / Q000097:blood; D004789:Enzyme Activation; D006801:Humans; D066298:In Vitro Techniques; D007700:Kinetics; D009504:Neutrophils / Q000201:enzymology*
D015777:Eicosanoids; D016718:Arachidonic Acid; D001094:Arachidonate 5-Lipoxygenase; D002118:Calcium