S 18886, a new thromboxane (TP)-receptor antagonist is the active isomer of S 18204 in all species, except in the guinea-pig.
Simonet
S
S
Servier Research Institute, Division of Angiology, Suresnes, France.
Descombes
J J
JJ
Vallez
M O
MO
Dubuffet
T
T
Lavielle
G
G
Verbeuren
T J
TJ
D019796:15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid / Q000494:pharmacology; D000818:Animals; D016084:Bronchoconstriction / Q000187:drug effects; D004285:Dogs; D006168:Guinea Pigs; D006801:Humans; D009119:Muscle Contraction / Q000187:drug effects*; D009130:Muscle, Smooth / Q000187:drug effects / Q000502:physiology; D009281:Naphthalenes; D010974:Platelet Aggregation / Q000187:drug effects*; D011422:Propionates; D011817:Rabbits; D017482:Receptors, Thromboxane / Q000037:antagonists & inhibitors*; D013045:Species Specificity; D013237:Stereoisomerism; D013764:Tetrahydronaphthalenes / Q000737:chemistry / Q000494:pharmacology*; D014132:Trachea / Q000502:physiology
D009281:Naphthalenes; D011422:Propionates; D017482:Receptors, Thromboxane; D013764:Tetrahydronaphthalenes; D019796:15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; C501362:terutroban