title: The epidemiology of Langerhans cell histiocytosis.
abstract: Little progress has been made in finding the causes of LCH. Epidemiologic studies are difficult because of the rarity of this disease. Although several associations have been demonstrated in case-control studies, particularly that with thyroid disease, no causal relationships have been documented. Additional case-control studies may uncover the to-date missing lead that may prove fruitful for epidemiologic investigation.
authors.affiliation: Department of Pediatrics, Oregon Health Sciences University/NRC5, Portland, USA.
authors.forename: H S
authors.initials: HS
authors.lastname: Nicholson
authors.forename: R M
authors.initials: RM
authors.lastname: Egeler
authors.forename: M E
authors.initials: ME
authors.lastname: Nesbit
mesh_terms: D002648:Child; D002675:Child, Preschool; D006646:Histiocytosis, Langerhans-Cell / Q000453:epidemiology*; D006801:Humans; D007223:Infant