[Clinical and therapeutic considerations in pseudomyxoma peritonei].
Pseudomyxoma peritonei (PMP) is an uncommon clinical entity, lacking a precisely defined etiopathogenesis. Its clinical features are not specific and diagnosis is difficult. We analysed 10 patients, all of them women, whom we had treated surgically in combination with intraperitoneal chemotherapy. Postoperative complications had been minimal and no death had occurred. 5 patients were followed up in time, 4 of them presenting a favourable evolution (2 required reintervention), and 1 patient decreased. We analysed up-to-date therapeutic approaches and the benefit of their combinations in order to identify the optimal therapeutic strategy. We consider that the combinations surgery + intraperitoneal chemotherapy or surgery + intracavitary radiotherapy are the most effective up to date.
Constantinoiu
S
S
Clinica de Chirurgie, Spitalul Clinic Sfânta Maria, UMF Carol Davila, Bucureşti, România.
Chiru
F
F
Mateş
I N
IN
Pop
D
D
Cochior
D
D
Bârlă
R
R
Dinu
D
D
Predescu
D
D
Predescu
V
V
D000328:Adult; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D007430:Intraoperative Care; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D010534:Peritoneal Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D011553:Pseudomyxoma Peritonei / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology / Q000601:surgery; D012189:Retrospective Studies