Dental problems associated with hypophosphataemic vitamin D resistant rickets.
OBJECTIVE
To review a series of cases of hypophosphataemic vitamin D resistant rickets. SUBJECTS INCLUDED: Seventeen cases, aged between 2 years 1 month and 15 years 9 months at first referral, and with an established diagnosis of vitamin D resistant rickets from twelve families were included in the review. Information was drawn from patient records for follow-up periods between 9 months and 20 years 4 months.


METHODS
All subjects had been referred to the Eastman Dental Hospital between 1973 and 1997.


RESULTS
Abscessed non-carious primary and/or permanent teeth were a presenting feature in eleven of the seventeen cases. Although attrition and exposure of the abnormally formed dentine accounted for the route of infection in primary teeth, the route for microbial invasion of pulpal tissues in permanent teeth remained unexplained in a number of patients. The possible part played by infractures of the enamel as a portal of entry for infection is discussed. Enamel defects were observed in only six patients, in three of whom these changes were limited to the primary dentition. Taurodontism of permanent molar teeth was confirmed as a feature of the condition in the more severely affected male subjects.
Goodman
J R
JR
Department of Paediatric Dentistry, Eastman Dental Hospital and Institute, London, UK.
Gelbier
M J
MJ
Bennett
J H
JH
Winter
G B
GB
D000038:Abscess / Q000000981:diagnostic imaging / Q000209:etiology*; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003743:Dental Enamel / Q000000981:diagnostic imaging; D003786:Dental Pulp Cavity / Q000002:abnormalities / Q000000981:diagnostic imaging; D003788:Dental Pulp Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D003804:Dentin / Q000000981:diagnostic imaging; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007015:Hypophosphatemia, Familial / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D011859:Radiography; D014076:Tooth Diseases / Q000000981:diagnostic imaging / Q000209:etiology*