Cyclosporine in the treatment of an unusual case of juvenile systemic sclerosis.
We describe a child who initially presented with juvenile dermatomyositis (JDM). Four years after the complete remission of JDM she developed systemic sclerosis without internal organ involvement. She was unresponsive to a combination of systemic corticosteroid therapy and pencillamine. The institution of cyclosporine induced a complete remission.
al-Mayouf
S M
SM
Department of Pediatrics, University of Toronto, The Hospital for Sick Children, Ontario, Canada.
Silverman
E D
ED
Feldman
B M
BM
Thorner
P
P
Laxer
R M
RM
D000293:Adolescent; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D016572:Cyclosporine / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D012595:Scleroderma, Systemic / Q000188:drug therapy*
D018501:Antirheumatic Agents; D016572:Cyclosporine