Identification of a human population infected with simian foamy viruses.
Studying the transmission of simian retroviruses to humans can help define the importance of these infections to public health. We identified a substantial prevalence (4/231, 1.8%) of infection with simian foamy viruses (SFV) among humans occupationally exposed to nonhuman primates. Evidence of SFV infection included seropositivity, proviral DNA detection and isolation of foamy virus. The infecting SFV originated from an African green monkey (one person) and baboons (three people). These infections have not as yet resulted in either disease or sexual transmission, and may represent benign endpoint infections.
Heneine
W
W
HIV and Retrovirology Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. WMH2@cdc.gov
Switzer
W M
WM
Sandstrom
P
P
Brown
J
J
Vedapuri
S
S
Schable
C A
CA
Khan
A S
AS
Lerche
N W
NW
Schweizer
M
M
Neumann-Haefelin
D
D
Chapman
L E
LE
Folks
T M
TM
D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002522:Chlorocebus aethiops; D006801:Humans; D008214:Lymphocytes / Q000821:virology; D008253:Macaca mulatta; D008297:Male; D009784:Occupational Diseases / Q000453:epidemiology*; D016273:Occupational Exposure; D002679:Pan troglodytes; D010215:Papio; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D015995:Prevalence; D018419:Primate Diseases; D012190:Retroviridae / Q000302:isolation & purification; D012192:Retroviridae Infections / Q000453:epidemiology / Q000635:transmission* / Q000662:veterinary; D016092:Spumavirus / Q000235:genetics / Q000302:isolation & purification; D015047:Zoonoses / Q000453:epidemiology*
D000914:Antibodies, Viral