Contact-angle analysis of intraocular lenses.
OBJECTIVE
To present contact-angle measurements of commercially available intraocular lenses (IOLs) in air and in water to facilitate the understanding of how various IOLs might interact in different environments.


METHODS
Laboratory.


METHODS
Five commercially available IOLs were studied: AMO DuraLens PS-59NB. AMO PhacoFlex SI-26NB, AMO PhacoFlex II SI-30NB, Chiron ChiroFlex C10UB, and Alcon AcrySof MA60BM. The AMO soft acrylic model AR40, currently under clinical study, was also evaluated. Contact-angle measurements were made in air and in water using sessile drop and captive bubble methods.


RESULTS
The sessile drop method indicated that all materials were hydrophobic in air. The captive bubble method differentiated materials based on their polar and dispersive forces.


CONCLUSIONS
Contact-angle measurements differed depending on the test conditions. Proper choice of contact-angle measurement method can generate useful information about a material surface and its potential biomaterial interactions.
Cunanan
C M
CM
Ghazizadeh
M
M
Buchen
S Y
SY
Knight
P M
PM
D000179:Acrylates / Q000737:chemistry* / Q000378:metabolism; D001672:Biocompatible Materials; D004577:Electron Probe Microanalysis; D007910:Lenses, Intraocular; D008855:Microscopy, Electron, Scanning; D019904:Polymethyl Methacrylate / Q000737:chemistry* / Q000378:metabolism; D012826:Silicone Elastomers / Q000737:chemistry* / Q000378:metabolism; D013500:Surface Tension; D014867:Water / Q000378:metabolism
D000179:Acrylates; D001672:Biocompatible Materials; D012826:Silicone Elastomers; D014867:Water; D019904:Polymethyl Methacrylate