Ethyl alcohol and dilative cardiomyopathy.
The ethanol-induced dilative cardiomyopathy has a complex clinical and paraclinical picture because of the direct action of the alcohol and the indirect action of its metabolites on human myocardium and neuroendocrine system. Ventricular arrhythmias, atrial arrhythmias, and heart failure are significant and show a great sensitivity of the conduction system. Working myocardium is also affected, which is proved by the impaired systolic and diastolic function of the heart and by the nitroglycerine-resistant isovolumetric relaxation time.
Stanciu
M
M
N. Gh. Lupu Clinical Hospital, Bucharest, Romania.
Câmpeanu
A
A
D000286:Administration, Sublingual; D000328:Adult; D002310:Cardiomyopathy, Alcoholic / Q000097:blood / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D002311:Cardiomyopathy, Dilated / Q000097:blood / Q000139:chemically induced* / Q000188:drug therapy / Q000503:physiopathology; D002784:Cholesterol / Q000097:blood; D000431:Ethanol / Q000009:adverse effects*; D006321:Heart / Q000187:drug effects / Q000503:physiopathology; D006801:Humans; D008274:Magnesium / Q000097:blood; D008297:Male; D005996:Nitroglycerin / Q000008:administration & dosage; D014280:Triglycerides / Q000097:blood; D014665:Vasodilator Agents / Q000008:administration & dosage
D014280:Triglycerides; D014665:Vasodilator Agents; D000431:Ethanol; D002784:Cholesterol; D005996:Nitroglycerin; D008274:Magnesium