Isoprenaline induces biosynthesis of proline-rich proteins in the salivary glands of rat but not in sheep.
Long-term treatment of rats with isoprenaline resulted in induction of proline-rich proteins (PRPs) in the salivary glands, which were subsequently purified by TCA solubility and column chromatography. When rats were removed from beta-agonist regimen, then these proteins were no longer observed. Treatment of sheep with isoprenaline did not reveal the induction of PRPs.
Haghighat
M
M
Department of Biochemistry, School of Veterinary Medicine, Shiraz University, Iran.
Moetamed
A
A
Vaseghi
T
T
Aminlari
M
M
D000318:Adrenergic beta-Agonists / Q000494:pharmacology*; D000818:Animals; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D007545:Isoproterenol / Q000494:pharmacology*; D008297:Male; D009929:Organ Size; D010306:Parotid Gland / Q000187:drug effects* / Q000378:metabolism; D010455:Peptides / Q000378:metabolism*; D055232:Proline-Rich Protein Domains; D051381:Rats; D017207:Rats, Sprague-Dawley; D012756:Sheep; D013363:Submandibular Gland / Q000187:drug effects* / Q000378:metabolism
D000318:Adrenergic beta-Agonists; D010455:Peptides; D007545:Isoproterenol