Evaluation of potential health effects of 10 kHz magnetic fields: a rodent reproductive study.
New technology involving the use of high-frequency inductive power distribution (HID) has recently been developed for use in materials handling and personnel transfer. Sinusoidal magnetic fields at a frequency of 10 kHz with field intensities of approximately 0.2 mT are generated directly between the current-carrying coils of this equipment. Effects of 10 kHz magnetic fields on cell division, migration, and differentiation have never been previously investigated. To evaluate potential effects on these parameters, a rodent reproductive study was undertaken using Wistar rats. Exposures were at 0.095, 0.24, and 0.95 mT with a background exposure of 5-10 microT. Three sets of parental rats were exposed continuously for 20-23.5 h/day to the fields: maternal rats during gestation, paternal rats for at least 45 days prior to mating and maternal rats 1 month prior to mating. Exposure phases thus covered spermatogenesis, maturation of the ovum and ovulation, fertilization, implantation, embryogenesis, organogenesis, and maturation of the fetus immediately prior to parturition. In all experiments pregnancy outcome was assessed. These studies failed to demonstrate any reproductive toxicity resulting from maternal or fetal exposure during gestation or following paternal or maternal exposure for several weeks prior to mating. No quantitative or qualitative effects on spermatogenesis occurred after exposure, and no effects on the estrous cycle or ovulation could be demonstrably linked to the 10 kHz magnetic field exposure at 0.095, 0.25, or 0.95 mT. Where possible, parental clinical chemistry and hematology were also examined. As in mouse toxicology studies previously reported, minor differences were observed between control and treated groups. These were regarded as statistically, but not biologically, significant and could not categorically be attributed to magnetic field exposure.
Dawson
B V
BV
Department of Anatomy, University of Auckland, New Zealand. b.dawson@auckland.ac.nz
Robertson
I G
IG
Wilson
W R
WR
Zwi
L J
LJ
Boys
J T
JT
Green
A W
AW
D000818:Animals; D005314:Embryonic and Fetal Development; D004971:Estrus; D005260:Female; D008098:Litter Size; D008280:Magnetics / Q000009:adverse effects*; D008297:Male; D051379:Mice; D011247:Pregnancy; D011256:Pregnancy Outcome; D051381:Rats; D017208:Rats, Wistar; D012098:Reproduction; D015430:Weight Gain