Cytologically negative carcinomatous meningitis: usefulness of CSF biochemical markers.
Eighteen patients (age range, 28 to 62 years; median, 58) with carcinomatous meningitis defined clinically (100%) and neuroradiographically (39%) with negative CSF cytology were evaluated with CSF biochemical markers. In only four patients (22%), CSF biochemical markers corroborated a diagnosis of carcinomatous meningitis.
Chamberlain
M C
MC
University of California, San Diego, La Jolla, CA, USA.
D000328:Adult; D015415:Biomarkers; D001943:Breast Neoplasms / Q000473:pathology; D002289:Carcinoma, Non-Small-Cell Lung / Q000473:pathology; D018288:Carcinoma, Small Cell / Q000473:pathology; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology; D008297:Male; D008545:Melanoma / Q000473:pathology; D008577:Meningeal Neoplasms / Q000134:cerebrospinal fluid* / Q000556:secondary*; D008581:Meningitis / Q000134:cerebrospinal fluid* / Q000209:etiology*; D008875:Middle Aged
D015415:Biomarkers