title: Human orosomucoid (ORM1) subtyping: further population genetic data and reports on the feasibility to type aged blood samples and stains.
abstract: Genetic polymorphism of serum orosomucoid (ORM1) was investigated in 1072 unrelated German Caucasians using isoelectric focusing followed by Western blotting and EIA. The estimated allele frequencies were ORM1 *F1 = 0.5690, ORM1 *S = 0.3927, ORM1 *F2 = 0.0368, ORM1 *F2S = 0.0009 and ORM1 *F5 = 0.0005. The method was successfully applied to determine ORM1 phenotypes in aged blood samples and blood stains. The results indicated that the ORM protein is a informative and remarkably robust blood group system.
authors.affiliation: Institut für Blutgruppenforschung, Köln, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Dülmer
authors.forename: G
authors.initials: G
authors.lastname: Reker
authors.forename: T T
authors.initials: TT
authors.lastname: Nguyen
authors.forename: L
authors.initials: L
authors.lastname: Henke
authors.forename: J
authors.initials: J
authors.lastname: Henke
mesh_terms: D000483:Alleles; D001793:Blood Preservation; D001801:Blood Stains; D004247:DNA / Q000032:analysis*; D016172:DNA Fingerprinting; D005240:Feasibility Studies; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D006801:Humans; D007525:Isoelectric Focusing; D009961:Orosomucoid / Q000235:genetics*; D011110:Polymorphism, Genetic; D013997:Time Factors
chemical_list: D005819:Genetic Markers; D009961:Orosomucoid; D004247:DNA