title: Update of the gene discovery program in Schistosoma mansoni with the expressed sequence tag approach.
abstract: Continuing the Schistosoma mansoni Genome Project 363 new templates were sequenced generating 205 more ESTs corresponding to 91 genes. Seventy four of these genes (81%) had not previously been described in S. mansoni. Among the newly discovered genes there are several of significant biological interest such as synaptophysin, NIFs-like and rho-GDP dissociation inhibitor.
authors.affiliation: Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.
authors.forename: E M
authors.initials: EM
authors.lastname: Rabelo
authors.forename: G R
authors.initials: GR
authors.lastname: Franco
authors.forename: V A
authors.initials: VA
authors.lastname: Azevedo
authors.forename: H B
authors.initials: HB
authors.lastname: Pena
authors.forename: T M
authors.initials: TM
authors.lastname: Santos
authors.forename: W S
authors.initials: WS
authors.lastname: Meira
authors.forename: N A
authors.initials: NA
authors.lastname: Rodrigues
authors.forename: J M
authors.initials: JM
authors.lastname: Ortega
authors.forename: S D
authors.initials: SD
authors.lastname: Pena
mesh_terms: D000818:Animals; D002874:Chromosome Mapping; D018509:DNA, Helminth; D016678:Genome; D012550:Schistosoma mansoni / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D016324:Sequence Tagged Sites
chemical_list: D018509:DNA, Helminth