title: Comparison of biochemical effects produced by calcium ions and by monomers of polyacrylamide (acrylamide and bisacrylamide) on strains of Saccharomyces cerevisiae used for production of chiral synthons.
abstract: The biochemical behaviour of four commercial strains of Saccharomyces cerevisiae was studied in the presence of calcium ions, acrylamide and bisacrylamide. Calcium ions at a concentration of 300 microM induced an increase of NAD(P)+ reduction in commercial Turkish and American strains, while in Chilean and Brazilian commercial strains, it diminished NAD(P)+ reduction. On the other hand, polyacrylamide monomers (acrylamide and bisacrylamide) induced a decrease of NAD(P)+ reduction in all strains studied in this paper. When membrane potential (delta psi) and oxygen consumption were measured in the presence of polyacrylamide monomers, a decrease of both was observed in all strains studied.
authors.affiliation: Yale University, School of Medicine, New Haven, CT 06520-8062, USA.
authors.forename: R
authors.initials: R
authors.lastname: de Souza Pereira
mesh_terms: D000178:Acrylamides / Q000494:pharmacology*; D000180:Acrylic Resins / Q000494:pharmacology; D000464:Alginates / Q000494:pharmacology; D001711:Biotransformation; D002118:Calcium / Q000494:pharmacology*; D003574:Cytochrome c Group / Q000378:metabolism; D020723:Glucuronic Acid; D006603:Hexuronic Acids; D008564:Membrane Potentials; D009249:NADP / Q000378:metabolism; D010084:Oxidation-Reduction; D010101:Oxygen Consumption; D012441:Saccharomyces cerevisiae / Q000187:drug effects / Q000378:metabolism*; D000099166:Polyacrylamides
chemical_list: D000178:Acrylamides; D000180:Acrylic Resins; D000464:Alginates; D002118:Calcium; D003574:Cytochrome c Group; D020723:Glucuronic Acid; D006603:Hexuronic Acids; D009249:NADP; D000099166:Polyacrylamides