Effect of acidic fibroblast growth factor (aFGF) on phagocytosis in mouse peritoneal macrophages.
The effects of acidic fibroblast growth factor (aFGF) on phagocytosis in peritoneal macrophages from thioglycollate-elicited mice were examined using flow cytometry. aFGF enhanced phagocytosis of fluorescein isothiocyanate-labeled latex particles in a dose-dependent manner. Basic fibroblast growth factor (bFGF) also enhanced phagocytosis. This study suggests that aFGF can modulate an important activity of macrophages.
Ichinose
M
M
Department of Physiology, Shimane Medical University, Japan. michinos@shimane-med.ac.jp
Sawada
M
M
Sasaki
K
K
Oomura
Y
Y
D000818:Animals; D016220:Fibroblast Growth Factor 1 / Q000096:biosynthesis / Q000494:pharmacology*; D005434:Flow Cytometry; D017737:Macrophages, Peritoneal / Q000187:drug effects* / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D010587:Phagocytosis / Q000187:drug effects* / Q000276:immunology
D016220:Fibroblast Growth Factor 1