title: The MAP kinase cascade: its role in Xenopus oocytes, eggs and embryos.
abstract: Mitogen-activated protein kinase (MAPK) was originally identified as a serine/threonine kinase that is activated by mitogens. Now MAPK and its activator, MAPK kinase (MAPKK), are thought to function in a wide variety of intracellular signalling pathways from yeast to vertebrate. We describe here a brief summary of the dissection of the MAPK cascade and its possible functions, especially in Xenopus oocytes and embryos.
authors.affiliation: Department of Genetics and Molecular Biology, Kyoto University, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Gotoh
authors.forename: E
authors.initials: E
authors.lastname: Nishida
mesh_terms: D000818:Animals; D017871:Calcium-Calmodulin-Dependent Protein Kinases / Q000502:physiology*; D008648:Mesoderm / Q000502:physiology; D020929:Mitogen-Activated Protein Kinase Kinases; D008938:Mitosis; D009865:Oocytes / Q000502:physiology; D011494:Protein Kinases / Q000502:physiology; D014981:Xenopus / Q000196:embryology / Q000502:physiology*
chemical_list: D011494:Protein Kinases; D017871:Calcium-Calmodulin-Dependent Protein Kinases; D020929:Mitogen-Activated Protein Kinase Kinases