[Heparin-associated thrombocytopenia (HAT) type II. An underestimated complication in prevention of thromboembolism with heparin].
We report four patients who developed heparin-associated thrombocytopenia (HAT) under heparin prophylaxis. One patient showed no clinical signs, but three had severe complications (white-clot syndrome, acute adrenal failure and loss of limb because of thromboembolic complication), leading to death in two cases.
Oberst
M
M
Abteilung für Unfallchirurgie, Klinikum der Stadt, Villingen-Schwenningen.
Vierling
P
P
Thielemann
F
F
D000368:Aged; D000369:Aged, 80 and over; D000925:Anticoagulants / Q000009:adverse effects* / Q000627:therapeutic use; D017809:Fatal Outcome; D005260:Female; D006493:Heparin / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000517:prevention & control*; D012307:Risk Factors; D013921:Thrombocytopenia / Q000139:chemically induced* / Q000175:diagnosis; D013923:Thromboembolism / Q000517:prevention & control*
D000925:Anticoagulants; D006493:Heparin