title: Glisoprenins C, D and E, new inhibitors of appressorium formation in Magnaporthe grisea, from cultures of Gliocladium roseum. 1. Production and biological activities.
abstract: Glisoprenins C, D, and E, new glisoprenin derivatives, were isolated together with glisoprenin A from submerged cultures of the deuteromycete Gliocladium roseum HA190-95. All glisoprenins inhibited appressorium formation in Magnaporthe grisea on inductive (hydrophobic) surfaces. The compounds exhibited moderate cytotoxic, but no antifungal, antibacterial or phytotoxic activities.
authors.affiliation: Lehrbereich Biotechnologie, University of Kaiserslautern, Germany.
authors.forename: E
authors.initials: E
authors.lastname: Thines
authors.forename: F
authors.initials: F
authors.lastname: Eilbert
authors.forename: H
authors.initials: H
authors.lastname: Anke
authors.forename: O
authors.initials: O
authors.lastname: Sterner
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000302:isolation & purification*; D001203:Ascomycota / Q000187:drug effects; D004791:Enzyme Inhibitors / Q000302:isolation & purification* / Q000494:pharmacology*; D005233:Fatty Alcohols / Q000302:isolation & purification* / Q000494:pharmacology*; D005285:Fermentation; D007769:Lactams; D008826:Microbial Sensitivity Tests; D003904:Mitosporic Fungi; D014407:Tumor Cells, Cultured / Q000187:drug effects
chemical_list: D000900:Anti-Bacterial Agents; D004791:Enzyme Inhibitors; D005233:Fatty Alcohols; D007769:Lactams; C111761:cremimycin; C111766:glisoprenin C; C111767:glisoprenin D; C111769:glisoprenin E; C077321:glisoprenin A