Thyroid parameters during therapy with zotepine in delusional depression. Preliminary results.
There are only few data on the effects of atpyical neuroleptics on thyroid function. In an open pilot study of 12 inpatients with delusional depression, thyroid hormone levels and TRH-TSH test were determined during neuroleptic treatment with zotepine. No significant changes in triiodothyronine (T3), thyroxine (T4) and delta-TSH levels were found in this observation period (28 days).
König
F
F
Weissenau Psychiatric Center, Department of Psychiatry I, University of Ulm, Ravensburg, Germany.
Hauger
B
B
Barg
T
T
Wolfersdorf
M
M
D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D003702:Delusions / Q000188:drug therapy* / Q000523:psychology; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology*; D003988:Dibenzothiepins / Q000009:adverse effects* / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D013960:Thyroid Function Tests; D013961:Thyroid Gland / Q000187:drug effects*; D013963:Thyroid Hormones / Q000097:blood
D014150:Antipsychotic Agents; D003988:Dibenzothiepins; D013963:Thyroid Hormones; C022172:zotepine