title: Induction of glutathione S-transferase activity in Triatoma infestans.
abstract: Several synthetic pesticides and allelochemicals used to treat Triatoma infestans adults by topic application showed some degree of cytosolic glutathione S-transferase (GST) induction. General inducers of detoxication systems such as phenobarbital and 3-methylcholantrene topically applied on T. infestans resulted in no GST induction. Meanwhile, general insecticide synergist such as piperonyl butoxide (160 micrograms/insect) increased the GST-activity in the range of 120-140%. Insects injected with reduced glutathione (300 mg/insect) presented at the forth day elevated GST activity.
authors.affiliation: Centro de Investigaciones de Plagas e Insecticidas-CIPEIN-(CITEFA-CONICET), Buenos Aires, Argentina.
authors.forename: J L
authors.initials: JL
authors.lastname: Sívori
authors.forename: N
authors.initials: N
authors.lastname: Casabé
authors.forename: E N
authors.initials: EN
authors.lastname: Zerba
authors.forename: E J
authors.initials: EJ
authors.lastname: Wood
mesh_terms: D000818:Animals; D004790:Enzyme Induction; D005982:Glutathione Transferase / Q000096:biosynthesis* / Q000187:drug effects*; D008297:Male; D013056:Spectrophotometry, Ultraviolet; D014224:Triatoma / Q000187:drug effects / Q000201:enzymology*
chemical_list: D005982:Glutathione Transferase