Tuberculosis due to drug-resistant Mycobacterium bovis in pregnancy.
We describe the management practices adopted in a case of pulmonary and extra-pulmonary tuberculosis caused by an isoniazid/pyrazinamide resistant strain of Mycobacterium bovis in a 26-week pregnant woman. She was initially treated with rifampin, isoniazid and ethambutol, pre-term delivery was induced and streptomycin was then added to the regimen. Screening of the new-born revealed no signs of either disease or infection. Isoniazid prophylaxis was not administered and the new-born was vaccinated and isolated from the mother for two months; however she continued to be fed with her mother's milk for the whole period.
Signorini
L
L
Clinic of Infectious and Tropical Diseases, University of Brescia, Italy.
Matteelli
A
A
Bombana
E
E
Pinsi
G
G
Gulletta
M
M
Tebaldi
A
A
Carosi
G
G
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D004641:Emigration and Immigration; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D009018:Morocco / Q000208:ethnology; D009163:Mycobacterium bovis / Q000187:drug effects* / Q000302:isolation & purification; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy / Q000382:microbiology*; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy / Q000382:microbiology*
D000995:Antitubercular Agents