title: Vascular permeability factor/vascular endothelial growth factor and vascular stroma formation in neoplasia. Insights from in situ hybridization studies.
abstract: The formation of vascular stroma plays an important role in the pathophysiology of malignancy. We describe the use of in situ hybridization in our laboratory as a tool to study the role of vascular permeability factor/vascular endothelial growth factor in the angiogenesis associated with malignancy.
authors.affiliation: Departments of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA.
authors.forename: L F
authors.initials: LF
authors.lastname: Brown
authors.forename: A J
authors.initials: AJ
authors.lastname: Guidi
authors.forename: K
authors.initials: K
authors.lastname: Tognazzi
authors.forename: H F
authors.initials: HF
authors.lastname: Dvorak
mesh_terms: D000818:Animals; D016228:Endothelial Growth Factors / Q000502:physiology*; D004730:Endothelium, Vascular / Q000473:pathology*; D006801:Humans; D017403:In Situ Hybridization; D008222:Lymphokines / Q000502:physiology*; D009369:Neoplasms / Q000098:blood supply* / Q000473:pathology; D009389:Neovascularization, Pathologic; D017154:Stromal Cells / Q000473:pathology; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors
chemical_list: D016228:Endothelial Growth Factors; D008222:Lymphokines; D042461:Vascular Endothelial Growth Factor A; D042442:Vascular Endothelial Growth Factors