title: Synthesis of new immunogens for estrone and estradiol-17 beta and antisera evaluation.
abstract: Syntheses of the 6 alpha-O-carboxymethyl ether derivatives of estrone and estradiol-17 beta and the preparation of their bovine serum albumin conjugates are described. The generation and evaluation of antisera produced from these conjugates is discussed.
authors.affiliation: Department of Organic Chemistry, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245-0549, USA.
authors.forename: P N
authors.initials: PN
authors.lastname: Rao
authors.forename: Z
authors.initials: Z
authors.lastname: Wang
authors.forename: J W
authors.initials: JW
authors.lastname: Cessac
authors.forename: P H
authors.initials: PH
authors.lastname: Moore
mesh_terms: D000818:Animals; D004958:Estradiol / Q000737:chemistry / Q000276:immunology*; D004970:Estrone / Q000737:chemistry / Q000276:immunology*; D005069:Evaluation Studies as Topic; D007106:Immune Sera; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D015394:Molecular Structure; D011817:Rabbits; D012710:Serum Albumin, Bovine / Q000737:chemistry; D014614:Vaccines, Synthetic / Q000737:chemistry*
chemical_list: D007106:Immune Sera; D014614:Vaccines, Synthetic; D012710:Serum Albumin, Bovine; D004970:Estrone; D004958:Estradiol