Laryngeal radionecrosis versus recurrent cancer: a clinical approach.
A group of 38 patients was studied by positron emission tomography utilizing fluorine18-labeled deoxyglucose (FDG-PET) scanning to examine the ability to differentiate postirradiation laryngeal recurrent cancer from radionecrosis. The resulting 79% correct diagnosis showed the technique to be far superior to conventional computed tomography scanning (61%) and clinical examination (43%). An algorithmic approach to evaluating and treating patients with radionecrosis and/or recurrent cancer by utilizing FDG-PET scanning is presented.
McGuirt
W F
WF
Department of Otolaryngology, Wake Forest University Medical Center, Winston-Salem, North Carolina 27157-1034, USA.
Greven
K M
KM
Keyes
J W
JW
Williams
D W
DW
Watson
N
N
D000465:Algorithms; D003937:Diagnosis, Differential; D019788:Fluorodeoxyglucose F18; D006801:Humans; D007822:Laryngeal Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy; D009336:Necrosis; D009364:Neoplasm Recurrence, Local; D009381:Neoplasms, Radiation-Induced / Q000000981:diagnostic imaging*; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging*; D011446:Prospective Studies; D011832:Radiation Injuries / Q000000981:diagnostic imaging*; D011878:Radiotherapy / Q000009:adverse effects*; D014055:Tomography, Emission-Computed
D019788:Fluorodeoxyglucose F18