[Is gene therapy of advanced prostatic carcinoma on the verge of clinical application?].
Gene transfer strategies for prostate cancer may yield promising future perspectives. In this regard, gene modified tumor vaccines, suicide gene therapy and gene replacement of nonfunctioning tumor suppressor genes are of special interest. Clinical phase I and early phase II studies with gene modified vaccines have to demonstrate the clinical implication of these new therapeutic options. Apart from this approach the development of more efficient delivery systems for in vivo gene transfer is highly desirable.
Gschwend
J E
JE
Urologische Universitätsklinik Ulm.
Hautmann
R E
RE
D019496:Cancer Vaccines / Q000235:genetics / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D018014:Gene Transfer Techniques; D015316:Genetic Therapy; D006801:Humans; D016233:Immunotherapy, Active; D008297:Male; D011471:Prostatic Neoplasms / Q000235:genetics / Q000276:immunology / Q000628:therapy*
D019496:Cancer Vaccines