[New putative gene from human retrovirus-containing locus on chromosome 19].
By means of cDNA selection, a cDNA clone corresponding to a putative gene was isolated. The identified gene was mapped to human chromosome 19 (region 19q12) to the locus containing the human endogenous retrovirus HERV-K LTR. The distance between the LTR and the cDNA fragment is about 20 kb. RT-PCR analysis of the total RNA revealed that the corresponding gene is preferentially expressed in the brain.
Khil'
P P
PP
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Lebedev
Iu B
IuB
Sverdlov
E D
ED
D001483:Base Sequence; D001921:Brain; D002874:Chromosome Mapping; D002888:Chromosomes, Human, Pair 19 / Q000235:genetics*; D003001:Cloning, Molecular; D004279:DNA, Viral / Q000235:genetics*; D015967:Gene Expression Regulation, Viral / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D016133:Polymerase Chain Reaction; D012091:Repetitive Sequences, Nucleic Acid; D012190:Retroviridae / Q000235:genetics*
D004279:DNA, Viral