Perineurioma of the finger: case report of a rare peripheral nerve sheath neoplasm of pure perineurial cell lineage.
A 1.9-cm extraneural soft tissue tumor located on the palmar aspect of the index finger of a 50-year-old woman was excised. Depicting many histopathologic patterns and a full range of cellularity, the tumor was exclusively composed of epithelial membrane antigen/vimentin-positive and S-100 protein/Leu-7-negative neoplastic cells of perineurial lineage. Soft tissue (extraneural) perineurioma, a rare variant of benign peripheral nerve sheath tumor, should be included in the differential diagnosis of tumor and tumor-like conditions affecting soft parts of the hand.
Bégin
L R
LR
Department of Pathology, McGill University and The Sir Mortimer B. Davis-Jewish General Hospital, Montreal, Quebec, Canada.
D018959:CD57 Antigens / Q000032:analysis; D019070:Cell Lineage; D003937:Diagnosis, Differential; D005260:Female; D005385:Fingers / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D018396:Mucin-1 / Q000032:analysis; D018317:Nerve Sheath Neoplasms / Q000473:pathology*; D010525:Peripheral Nerves / Q000473:pathology; D009418:S100 Proteins / Q000032:analysis; D012983:Soft Tissue Neoplasms / Q000473:pathology*; D014746:Vimentin / Q000032:analysis
D018959:CD57 Antigens; D018396:Mucin-1; D009418:S100 Proteins; D014746:Vimentin