Risk factors associated with the acquisition of amikacin-resistant gram-negative bacilli in central New Jersey hospitals.
A case-control study was performed in central New Jersey hospitals to evaluate the potential patient factors associated with the acquisition of amikacin-resistant gram-negative bacilli (ARGNB). Univariate analysis revealed an association between numerous patient factors, and multivariate analysis revealed four factors to be associated independently with ARGNB: the number of hospital admissions during the prior year, previous aminoglycoside exposure, intubation, and intensive-care-unit admission.
Jessop
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AB
John
J F
JF
Paul
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SM
D000583:Amikacin / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D016022:Case-Control Studies; D004352:Drug Resistance, Microbial; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000302:isolation & purification*; D006801:Humans; D007362:Intensive Care Units; D007440:Intubation / Q000009:adverse effects; D009515:New Jersey; D012044:Regression Analysis; D012307:Risk Factors
D000900:Anti-Bacterial Agents; D000583:Amikacin