title: Ropivacaine in paediatric surgery: preliminary results.
abstract: In a double blind study 40 patients, aged 1-9 years, undergoing elective minor surgery were examined and randomly divided in two groups (20 children each). After light general anaesthesia Group 1 received caudal injection of bupivacaine 0.25% 2 mg.kg-1 while Group 2 received 0.2% ropivacaine 2 mg.kg-1. No differences were observed in demographic data, HR, BP and duration of surgery; the onset time of anaesthesia was 12 min and 9 min in Group 1 and 2 respectively. Ten patients in Group 1 received paracetamol in the first 24 h after surgery while only two children in Group 2 needed analgesic; even the duration of analgesia in the patients requiring paracetamol was superior in group 2 (520 min vs 253 min). No motor block was apparent at awakening in either group and no side effect was noticed. In conclusion ropivacaine seems to be an effective and safe drug in paediatric regional anaesthesia.
authors.affiliation: Department of Anaesthesia, Gaslini Children's Hospital, Genoa, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Ivani
authors.forename: N
authors.initials: N
authors.lastname: Mereto
authors.forename: E
authors.initials: E
authors.lastname: Lampugnani
authors.forename: P D
authors.initials: PD
authors.lastname: Negri
authors.forename: M
authors.initials: M
authors.lastname: Torre
authors.forename: G
authors.initials: G
authors.lastname: Mattioli
authors.forename: V
authors.initials: V
authors.lastname: Jasonni
authors.forename: P A
authors.initials: PA
authors.lastname: Lönnqvist
mesh_terms: D000577:Amides / Q000008:administration & dosage / Q000009:adverse effects; D015360:Analgesia, Epidural; D000768:Anesthesia, General; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000009:adverse effects; D002045:Bupivacaine / Q000008:administration & dosage; D002648:Child; D002675:Child, Preschool; D004311:Double-Blind Method; D006801:Humans; D007223:Infant; D013511:Minor Surgical Procedures; D000077212:Ropivacaine
chemical_list: D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine; D002045:Bupivacaine