Salivary immune responses after gingival immunization with tetravaccinal and bivaccinal formulations of inactivated micro-organisms.
Two groups of rats were treated separately, fourteen times during three months, by rubbing at gingival mucosa with two antigenic mixtures: (i) Staph. aureus, Str. faecalis, E. coli and Prot. vulgaris; (ii) Str. mutans and Act. viscosus. At the end of the treatments the increases of specific salivary IgAGM ranged from 202.6% (Str. faecalis) to 312.7% (E. coli) in the case of tetravaccinal association and from 123% (Act. viscosus) to 171.4% (Str. mutans) in the one of bivaccinal formulation.
Casetta
P
P
Chair of Microbiology and Hygiene, University of Milan, Italy.
Negretti
F
F
D000818:Animals; D001428:Bacterial Vaccines / Q000008:administration & dosage / Q000276:immunology / Q000627:therapeutic use*; D005260:Female; D005881:Gingiva; D007114:Immunization / Q000379:methods*; D009061:Mouth Mucosa / Q000276:immunology; D051381:Rats; D017207:Rats, Sprague-Dawley; D012469:Salivary Glands / Q000276:immunology*; D015164:Vaccines, Inactivated / Q000008:administration & dosage / Q000276:immunology / Q000627:therapeutic use*
D001428:Bacterial Vaccines; D015164:Vaccines, Inactivated