The Synthesis of Phycopsisenone, a New Phenolic Secondary Metabolite from the Sponge Phycopsis sp.
A short first total synthesis of phycopsisenone (1) utilizing microwave irradiation-induced aldol condensation and TiCl4-catalyzed reaction of silyl enol ether (3) with acetone as key steps has been achieved in 29.4% overall yield.
Kad
GL
Department of Chemistry, Panjab University, Chandigarh 160014, India.
Singh
V
Khurana
A
Singh
J