Stroke from internal carotid artery occlusion during mumps infection.
During the terminal incubation period of severe mumps infection, a 40-year-old patient suffered from large infarction in the right middle cerebral artery territory. The proximal right internal carotid artery (ICA) was occluded on angiography. Computed tomography of the neck detected a hemorrhage located ventromedial to the right common carotid artery. Four months later the right ICA was partly recanalized. Carotid surgery revealed an atherosclerotic plaque and a vessel wall, which was fragile and less compact than usually. A strong inflammatory reaction to mumps infection may have contributed to the pathogenesis of the cervical hemorrhage and to acute thrombosis and occlusion of the ICA.
Grau
A J
AJ
Department of Neurology, University of Heidelberg, Germany.
Eckstein
H H
HH
Schäfer
B
B
Schnabel
P A
PA
Brandt
T
T
Hacke
W
W
D000328:Adult; D002340:Carotid Artery Diseases / Q000209:etiology* / Q000473:pathology; D002343:Carotid Artery, Internal / Q000473:pathology*; D002533:Cerebral Angiography; D002561:Cerebrovascular Disorders / Q000209:etiology* / Q000473:pathology; D006429:Hemiplegia / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D009107:Mumps / Q000150:complications*; D014057:Tomography, X-Ray Computed