title: Temperature sensitivity of bacteriolysis induced by beta-lactam antibiotics in amino acid-deprived Escherichia coli.
abstract: The temperature-sensitive penicillin tolerance response previously reported in amino acid-deprived Escherichia coli (W. Kusser and E. E. Ishiguro, J. Bacteriol. 169:2310-2312, 1987) was not due to the induction of the heat shock response resulting from a temperature upshift and was therefore unrelated to the findings of another report (J. K. Powell and K. D. Young, J. Bacteriol. 173:4021-4026, 1991) indicating a positive correlation between the expression of heat shock proteins and penicillin tolerance. The thermosensitive event occurred in the lysis induction stage.
authors.affiliation: Department of Biochemistry and Microbiology, University of Victoria, British Columbia, Canada.
authors.forename: D G
authors.initials: DG
authors.lastname: Rodionov
authors.forename: E E
authors.initials: EE
authors.lastname: Ishiguro
mesh_terms: D000596:Amino Acids / Q000378:metabolism*; D000667:Ampicillin / Q000494:pharmacology*; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001433:Bacteriolysis / Q000187:drug effects / Q000502:physiology*; D002701:Chloramphenicol / Q000494:pharmacology*; D004347:Drug Interactions; D004926:Escherichia coli / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D007700:Kinetics; D013696:Temperature; D013997:Time Factors
chemical_list: D000596:Amino Acids; D000900:Anti-Bacterial Agents; D002701:Chloramphenicol; D000667:Ampicillin