title: Stroke from internal carotid artery occlusion during mumps infection.
abstract: During the terminal incubation period of severe mumps infection, a 40-year-old patient suffered from large infarction in the right middle cerebral artery territory. The proximal right internal carotid artery (ICA) was occluded on angiography. Computed tomography of the neck detected a hemorrhage located ventromedial to the right common carotid artery. Four months later the right ICA was partly recanalized. Carotid surgery revealed an atherosclerotic plaque and a vessel wall, which was fragile and less compact than usually. A strong inflammatory reaction to mumps infection may have contributed to the pathogenesis of the cervical hemorrhage and to acute thrombosis and occlusion of the ICA.
authors.affiliation: Department of Neurology, University of Heidelberg, Germany.
authors.forename: A J
authors.initials: AJ
authors.lastname: Grau
authors.forename: H H
authors.initials: HH
authors.lastname: Eckstein
authors.forename: B
authors.initials: B
authors.lastname: Schäfer
authors.forename: P A
authors.initials: PA
authors.lastname: Schnabel
authors.forename: T
authors.initials: T
authors.lastname: Brandt
authors.forename: W
authors.initials: W
authors.lastname: Hacke
mesh_terms: D000328:Adult; D002340:Carotid Artery Diseases / Q000209:etiology* / Q000473:pathology; D002343:Carotid Artery, Internal / Q000473:pathology*; D002533:Cerebral Angiography; D002561:Cerebrovascular Disorders / Q000209:etiology* / Q000473:pathology; D006429:Hemiplegia / Q000209:etiology / Q000473:pathology; D006801:Humans; D008297:Male; D009107:Mumps / Q000150:complications*; D014057:Tomography, X-Ray Computed