title: Myoepithelial carcinoma (malignant myoepithelioma): first report of an occurrence in the maxillary sinus.
abstract: OBJECTIVE
  We document for the first time the occurrence of a malignant myoepithelioma at a site other than within the major and minor salivary glands.
  
  
  RESULTS
  A 67-year-old male presented with progressive symptoms and signs of a space-occupying lesion in the right maxillary sinus. An initial biopsy identified a malignant (myo)epithelial lesion and a radical maxillectomy was performed. Histology, supplemented by immunohistochemistry, confirmed the presence of a malignant myoepithelioma.
  
  
  CONCLUSIONS
  Malignant myoepithelioma is a very rare tumour composed almost exclusively of myoepithelial cells and, to date, has only been described arising in the the major and minor salivary glands. A variety of tumours of salivary tissue have been reported within the head and neck area at sites outside the major and minor salivary glands, probably arising within accessory salivary tissue. We report the first case of a malignant myoepithelioma occurring in the maxillary sinus, also presumably arising in accessory salivary tissue in this location.
authors.affiliation: Department of Pathology, Leiden University Medical Centre, The Netherlands.
authors.forename: J F
authors.initials: JF
authors.lastname: Graadt van Roggen
authors.forename: R J
authors.initials: RJ
authors.lastname: Baatenberg-de Jong
authors.forename: H P
authors.initials: HP
authors.lastname: Verschuur
authors.forename: J C
authors.initials: JC
authors.lastname: Balhuizen
authors.forename: P J
authors.initials: PJ
authors.lastname: Slootweg
authors.forename: J H
authors.initials: JH
authors.lastname: van Krieken
mesh_terms: D000368:Aged; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008444:Maxillary Sinus Neoplasms / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D009208:Myoepithelioma / Q000209:etiology / Q000378:metabolism / Q000473:pathology*; D009418:S100 Proteins / Q000378:metabolism
chemical_list: D009418:S100 Proteins