title: Premedication for neonatal intubation.
abstract: The incidence of complications was recorded for 269 consecutive neonatal endotracheal intubations after instituting a routine policy of premedication. Two hundred and fifty-three of the intubations were premedicated with a combination of atropine, fentanyl and succinylcholine, 194 were without incident, 28 required two attempts, 22 required more than two attempts, and 9 required a second attempt with a smaller endotracheal tube. All infants were successfully intubated. We conclude that a policy of routine neonatal premedication for intubation is safe, feasible, and humane.
authors.affiliation: University of California, San Diego, Medical Center, 92103-8774, USA.
authors.forename: K J
authors.initials: KJ
authors.lastname: Barrington
authors.forename: P J
authors.initials: PJ
authors.lastname: Byrne
mesh_terms: D000759:Adjuvants, Anesthesia / Q000008:administration & dosage / Q000627:therapeutic use; D018686:Anesthetics, Intravenous / Q000008:administration & dosage / Q000627:therapeutic use; D001285:Atropine / Q000008:administration & dosage / Q000627:therapeutic use; D001724:Birth Weight / Q000502:physiology; D015331:Cohort Studies; D005283:Fentanyl / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007231:Infant, Newborn / Q000502:physiology*; D007385:Intermittent Positive-Pressure Ventilation; D007442:Intubation, Intratracheal / Q000009:adverse effects / Q000379:methods*; D009467:Neuromuscular Depolarizing Agents / Q000008:administration & dosage / Q000627:therapeutic use; D011292:Premedication / Q000009:adverse effects / Q000379:methods*; D013390:Succinylcholine / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D000759:Adjuvants, Anesthesia; D018686:Anesthetics, Intravenous; D009467:Neuromuscular Depolarizing Agents; D001285:Atropine; D013390:Succinylcholine; D005283:Fentanyl