Tubulin family: kinship of key proteins across phylogenetic domains.
Atomic structures obtained by electron microscopy for tubulin, and by X-ray crystallography for bacterial FtsZ, show that the two proteins are highly homologous. The complementarity between such high-resolution studies and low-resolution reconstructions of microtubule complexes is clear, but controversy still abounds.
Egelman
E H
EH
Department of Cell Biology and Neuroanatomy, University of Minnesota Medical School, 321 Church Street SE, Minneapolis, Minnesota 55455, USA. egelman@ege12.med.numn.edu
D001426:Bacterial Proteins / Q000737:chemistry*; D018360:Crystallography, X-Ray; D003598:Cytoskeletal Proteins; D008854:Microscopy, Electron; D008870:Microtubules / Q000737:chemistry; D008958:Models, Molecular; D010802:Phylogeny; D014404:Tubulin / Q000737:chemistry*
D001426:Bacterial Proteins; D003598:Cytoskeletal Proteins; C071525:FtsZ protein, Bacteria; D014404:Tubulin