title: Fetal tissue typing in anticipation of neonatal heart transplantation.
abstract: BACKGROUND
  Hypoplastic left heart syndrome is among the most common major congenital cardiac anomalies. Fetuses with this anomaly survive but require either reconstructive surgery or heart transplantation postnatally.
  
  
  METHODS
  A woman whose fetus was diagnosed with hypoplastic left heart syndrome underwent funipuncture for fetal tissue typing. The fetus then was listed for heart transplantation. Once an ABO-compatible donor heart was procured, the fetus was delivered and immediately underwent transplantation.
  
  
  CONCLUSIONS
  In candidates for neonatal heart transplantation, fetal tissue typing allows the search for an ABO-compatible donor heart to begin earlier. This approach minimizes the morbidity associated with postnatal waiting and allows transplantation to take place while the neonate is less immunocompetent.
authors.affiliation: Department of Obstetrics and Gynecology, University of Miami School of Medicine, Florida 33101-6960, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Gilles
authors.forename: G
authors.initials: G
authors.lastname: Burkett
authors.forename: R A
authors.initials: RA
authors.lastname: Perryman
authors.forename: P L
authors.initials: PL
authors.lastname: Ferrer
mesh_terms: D000017:ABO Blood-Group System; D000328:Adult; D005260:Female; D005312:Fetal Blood; D005333:Fetus / Q000276:immunology*; D016027:Heart Transplantation; D006650:Histocompatibility Testing; D006801:Humans; D018636:Hypoplastic Left Heart Syndrome / Q000175:diagnosis / Q000601:surgery*; D007231:Infant, Newborn; D011247:Pregnancy; D011296:Prenatal Diagnosis
chemical_list: D000017:ABO Blood-Group System