Sensitivity of carbohydrate-deficient transferrin (CDT) in relation to age and duration of abstinence.
Carbohydrate-deficient transferrin (CDT) serum concentrations were prospectively determined in 162 subjects (alcoholics n=62, controls n=100) using three different methods of detection (IEF, CDTect, Axis%CDT). Repeated testing in alcoholics after 3 and 5 days of abstinence demonstrated a significantly higher sensitivity of CDT in patients above 40 years of age compared to younger patients.
Agelink
M W
MW
Department of Psychiatry, University of Bochum, Evangl. Hospital Gelsenkirchen, Germany.
Dirkes-Kersting
A
A
Zeit
T
T
Bertling
R
R
Malessa
R
R
Klieser
E
E
D000328:Adult; D000368:Aged; D000375:Aging / Q000378:metabolism*; D000428:Alcohol Drinking / Q000097:blood*; D015415:Biomarkers; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D013695:Temperance; D013997:Time Factors; D014168:Transferrin / Q000031:analogs & derivatives* / Q000378:metabolism
D015415:Biomarkers; D014168:Transferrin; C056759:carbohydrate-deficient transferrin