Esophagolaryngeal reflex in a porcine animal model.
OBJECTIVE
The purpose of this study was to determine the effect of stimulation of the distal esophagus upon tension in the thyroarytenoid muscles.


METHODS
Stimulation of the distal esophagus of six anaesthetized female pigs by means of balloon dilatation and acid infusion was performed. Response was measured with electromyography of the thyroarytenoid muscles.


RESULTS
Acid infusion into the distal esophagus showed a statistically significant response in the thyroaytenoid muscles. Response to balloon dilatation was marked but not statistically significant.


CONCLUSIONS
Stimulation of the distal esophagus during episodes of gastroesophageal reflux may play a causative role in producing some of the symptoms that otolaryngologists treat on a daily basis.
Gill
C
C
Department of Surgery, University of British Columbia, Vancouver.
Morrison
M D
MD
D000818:Animals; D002404:Catheterization; D004195:Disease Models, Animal; D004576:Electromyography; D004947:Esophagus / Q000503:physiopathology*; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications* / Q000503:physiopathology*; D006685:Hoarseness / Q000209:etiology*; D007821:Laryngeal Muscles / Q000503:physiopathology*; D010612:Pharyngitis / Q000209:etiology*; D012018:Reflex; D013552:Swine