Tiotidine, a classical H2-antagonist, presents characteristics of an inverse agonist in U937 cell line.
Monczor
F
F
Laboratorio de Radioisótopos, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.
Legnazzi
B L
BL
Rivera
E
E
Davio
C
C
D002927:Cimetidine / Q000031:analogs & derivatives* / Q000494:pharmacology; D000242:Cyclic AMP / Q000032:analysis / Q000378:metabolism; D004305:Dose-Response Relationship, Drug; D006146:Guanidines / Q000494:pharmacology; D017442:Histamine Agonists / Q000494:pharmacology; D006635:Histamine H2 Antagonists / Q000494:pharmacology*; D006801:Humans; D007093:Imidazoles / Q000494:pharmacology; D016403:Lymphoma, Large B-Cell, Diffuse; D011970:Receptors, Histamine H2 / Q000145:classification / Q000187:drug effects; D014407:Tumor Cells, Cultured
D006146:Guanidines; D017442:Histamine Agonists; D006635:Histamine H2 Antagonists; D007093:Imidazoles; D011970:Receptors, Histamine H2; C069358:BU-E 75; D002927:Cimetidine; D000242:Cyclic AMP; C023990:tiotidine