title: An unusual case of primary systemic amyloidosis.
abstract: Here we report an unusual case of primary systemic amyloidosis. The cutaneous lesions were polymorphic and included involvement of both external auditory canals. The visceral involvement was covert. Mapping of amyloid deposits was performed using scintigraphy with technetium-99m (V) dimercaptosuccinic acid ([99mTc (V)] DMSA). Therapy with melphalan, prednisone and colchicine resulted in considerable improvement.
authors.affiliation: Istituto di Clinica Medica-Reumatologia, Seconda Università di Napoli, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Ambrosone
authors.forename: L
authors.initials: L
authors.lastname: Mansi
authors.forename: T
authors.initials: T
authors.lastname: Salvatore
authors.forename: F
authors.initials: F
authors.lastname: Marino
authors.forename: P
authors.initials: P
authors.lastname: Orabona
authors.forename: A
authors.initials: A
authors.lastname: Rambaldi
authors.forename: P F
authors.initials: PF
authors.lastname: Rambaldi
authors.forename: M
authors.initials: M
authors.lastname: Rambaldi
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D018906:Antineoplastic Agents, Alkylating / Q000627:therapeutic use; D003078:Colchicine / Q000627:therapeutic use; D005260:Female; D006074:Gout Suppressants / Q000627:therapeutic use; D006801:Humans; D008558:Melphalan / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D011877:Radionuclide Imaging; D012871:Skin Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D019783:Technetium Tc 99m Dimercaptosuccinic Acid
chemical_list: D000893:Anti-Inflammatory Agents; D018906:Antineoplastic Agents, Alkylating; D006074:Gout Suppressants; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D008558:Melphalan; D003078:Colchicine; D011241:Prednisone