Neural progenitors and stem cells: mechanisms of progenitor heterogeneity.
Heterogeneity among progenitor cells in the vertebrate nervous system has been documented with increasing frequency over the past few years. It has become clear that differences in progenitor cells help to determine when and how they respond to environmental signals. More recent studies have begun to elucidate the molecular basis of the differences in progenitor cell subpopulations that control their developmental potential and responsiveness to environmental signals.
Lillien
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Department of Neurobiology, University of Pittsburgh School of Medicine, Pennsylvania 15261, USA. lillien+@pitt.edu
D000818:Animals; D019070:Cell Lineage / Q000502:physiology; D005260:Female; D006801:Humans; D009420:Nervous System / Q000166:cytology / Q000196:embryology* / Q000254:growth & development*; D009474:Neurons / Q000502:physiology*; D011247:Pregnancy; D013234:Stem Cells / Q000502:physiology*