'Alice in Wonderland' syndrome as a precursor of depressive disorder.
A 54-year-old Japanese businessman who was found to exhibit the 'Alice in Wonderland' syndrome and went on to develop a depressive disorder is described. Lengthening and shortening of time experience continued intermittently for about 3 months, and metamorphopsia, distortion of body image, and the quick-motion phenomenon (alteration in time sense) persisted for almost 2 days without interruption. There were no abnormal physical findings. The authors review studies on 'Alice in Wonderland' syndrome and suggest that depressive illness may be a causal factor.
Mizuno
M
M
Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan.
Kashima
H
H
Chiba
H
H
Murakami
M
M
Asai
M
M
D001828:Body Image; D003861:Depersonalization / Q000175:diagnosis / Q000523:psychology; D003866:Depressive Disorder / Q000175:diagnosis* / Q000523:psychology; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D010469:Perceptual Distortion; D013577:Syndrome; D013998:Time Perception