Absidia corymbifera infections in neonates.
We report the first two documented cases of neonatal zygomycosis caused by Absidia corymbifera. A premature infant developed disseminated disease from a cutaneous site with pulmonary, gastrointestinal, and cerebral involvement. The infant died despite amphotericin B therapy and surgical debridement. The second case occurred in a full-term infant with congenital heart disease and fungal pneumonitis. Zygomycosis was not suspected because of underlying cardiac disease and a complicated postoperative course, and this infant also died. Absidia joins a growing list of opportunistic fungal pathogens of the compromised neonate.
Amin
S B
SB
Department of Pediatrics, Children's Hospital at Strong, Rochester, New York 14642, USA.
Ryan
R M
RM
Metlay
L A
LA
Watson
W J
WJ
D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009090:Mucorales; D009091:Mucormycosis / Q000188:drug therapy / Q000473:pathology