Lipodystrophia centrifugalis abdominalis infantilis.
OBJECTIVE
To describe the clinical features of lipodystrophia centrifugalis abdominalis infantilis (LCAI) with special attention to the erythema which is seen around the depressed lesion.


BACKGROUND
LCAI is a rare disorder which occurs mainly in Asian people, particularly in Japanese; it usually begins as an erythematous macule which subsequently expands centrifugally and leaves a central depression. However, the erythema has been seldom documented in detail. We here report a case of LCAI observed from its early stage and review the literature.


METHODS
A 2-year-old Japanese girl was brought to our out-patient clinic. Clinical examination revealed a slight depression surrounded by faint erythema that mimicked morphea on her left inguinum, but there was no hardening of the skin. The erythema disappeared 5 months after onset. Thereafter, the lipodystrophy expanded irrespective of the treatment to her right inguinum and lower abdomen.


CONCLUSIONS
The depression continues to grow without the erythema in most patients. This suggests that the erythema is not necessary for enlargement of the depression although it precedes the depression in most patients.
Takeda
H
H
Department of Dermatology, Yamagata University School of Medicine, Yamagata, Japan.
Mitsuhashi
Y
Y
Ishizawa
T
T
Kondo
S
S
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001707:Biopsy, Needle; D002675:Child, Preschool; D003937:Diagnosis, Differential; D018450:Disease Progression; D004890:Erythema / Q000209:etiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008060:Lipodystrophy / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use; D012594:Scleroderma, Localized / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology
D000893:Anti-Inflammatory Agents; D011239:Prednisolone