title: Advances in periodontal diagnosis. 4. Potential microbiological markers.
abstract: The potential of bacterial markers for the detection of periodontal disease activity is discussed. Chronic periodontitis has been associated with subgingival bacteria. Techniques are available to detect and distinguish different bacteria. In subgingival plaque, bacterial proteases can be detected. Commercial diagnostic tests based on bacterial factors are described.
authors.affiliation: Periodontal Department, King's College School of Medicine and Dentistry, Denmark Hill, London.
authors.forename: B M
authors.initials: BM
authors.lastname: Eley
authors.forename: S W
authors.initials: SW
authors.lastname: Cox
mesh_terms: D001421:Bacteria, Anaerobic / Q000201:enzymology / Q000302:isolation & purification; D001587:Benzoylarginine-2-Naphthylamide; D015415:Biomarkers; D004796:Clinical Enzyme Tests; D015342:DNA Probes; D004269:DNA, Bacterial / Q000032:analysis; D003773:Dental Plaque / Q000201:enzymology / Q000382:microbiology; D010450:Endopeptidases / Q000032:analysis; D004797:Enzyme-Linked Immunosorbent Assay; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D010510:Periodontal Diseases / Q000175:diagnosis* / Q000382:microbiology*; D011933:Reagent Kits, Diagnostic
chemical_list: D015415:Biomarkers; D015342:DNA Probes; D004269:DNA, Bacterial; D011933:Reagent Kits, Diagnostic; D001587:Benzoylarginine-2-Naphthylamide; D010450:Endopeptidases