[Drug delivery system in cardiovascular drugs].
Various drug delivery systems are available when cardiovascular drugs are used. Various kinds of receptor inhibitors such as beta blockade or angiotensin II receptor inhibitor are frequently used in the daily cardiovascular clinic. Several different routes of drug administration exist. Conventional tablet or its liquid spray by sublingual or lingual administration is rapidly absorbed and specified oral tablet or transdermal patch for maintaining longtime is slowly absorbed from the digestive tract or skin. Some drugs have different type of tablets for obtaining different pharmacodynamics. Nifedipine has 3 kinds of tablets showing short, long and very long-time effect. Recent advance in drug delivery system makes possible to administer the drug to the small local area through stent or balloon catheter at the coronary interventional therapy.
Miyake
F
F
Second Department of Internal Medicine, St. Marianna University School of Medicine.
Kamogawa
A
A
Sakakibara
M
M
D015906:Angioplasty, Balloon, Coronary; D002317:Cardiovascular Agents / Q000008:administration & dosage* / Q000493:pharmacokinetics; D002318:Cardiovascular Diseases / Q000628:therapy; D004333:Drug Administration Routes; D016503:Drug Delivery Systems; D006801:Humans; D012008:Recurrence; D015607:Stents
D002317:Cardiovascular Agents