SLE: mechanisms of vascular injury.
The chronic elevation of complement split products seen in many patients with systemic lupus erythematosus should be regarded as equivalent to silent hypertension, or hyperglycemia in a patient with incipient diabetes mellitus. Although the consequences may not be immediately evident, such patients should be monitored and perhaps even treated.
Abramson
S B
SB
New York University, USA.
Belmont
H M
HM
D000328:Adult; D000936:Antigen-Antibody Complex / Q000276:immunology*; D016736:Antiphospholipid Syndrome / Q000209:etiology; D003167:Complement Activation / Q000276:immunology*; D004730:Endothelium, Vascular / Q000276:immunology; D005260:Female; D006801:Humans; D007962:Leukocytes / Q000276:immunology; D008180:Lupus Erythematosus, Systemic / Q000150:complications* / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D012008:Recurrence; D013927:Thrombosis / Q000209:etiology; D014652:Vascular Diseases / Q000209:etiology*
D000936:Antigen-Antibody Complex