title: Sleep in asthma.
abstract: The nocturnal worsening of asthma is a major cause of morbidity and mortality from this disease. The physiologic changes that occur during normal sleep can have adverse effects on breathing patterns, arousal responses, and airway clearance in asthmatics. Understanding of these alterations in airway mechanics and airway inflammation may lead to better management of this disease.
authors.affiliation: Department of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: C M
authors.initials: CM
authors.lastname: D'Ambrosio
authors.forename: V
authors.initials: V
authors.lastname: Mohsenin
mesh_terms: D000328:Adult; D000403:Airway Resistance; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D016535:Bronchial Hyperreactivity / Q000503:physiopathology*; D001993:Bronchodilator Agents / Q000627:therapeutic use; D002940:Circadian Rhythm; D005260:Female; D005764:Gastroesophageal Reflux / Q000150:complications; D006801:Humans; D008176:Lung Volume Measurements; D008297:Male; D015656:Respiratory Mechanics / Q000502:physiology*; D012890:Sleep / Q000502:physiology*; D012891:Sleep Apnea Syndromes / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*
chemical_list: D001993:Bronchodilator Agents