Can clinically relevant histamine release be accurately diagnosed in anaesthetised patients without plasma histamine measurements? Randomised study with nested sampling aimed to change paradigms.
Duda
D
D
Clinic of Anaesthesiology, Johannes Gutenberg University, Mainz Germany. duda@goofy.zdv.uni-mainz.de
Lorenz
W
W
Dick
W
W
Celik
I
I
Black
A
A
Healy
M J
MJ
Black
J W
JW
D000707:Anaphylaxis / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control; D000758:Anesthesia / Q000009:adverse effects*; D000777:Anesthetics / Q000008:administration & dosage / Q000009:adverse effects; D001794:Blood Pressure / Q000187:drug effects; D006339:Heart Rate / Q000187:drug effects; D006632:Histamine / Q000097:blood; D006634:Histamine H1 Antagonists / Q000494:pharmacology / Q000627:therapeutic use*; D006635:Histamine H2 Antagonists / Q000494:pharmacology / Q000627:therapeutic use*; D006636:Histamine Release / Q000187:drug effects*; D006801:Humans
D000777:Anesthetics; D006634:Histamine H1 Antagonists; D006635:Histamine H2 Antagonists; D006632:Histamine