Preparation of two dosage forms containing antitumor prostaglandin and their antitumor effect in vitro and in vivo: Lipiodol solution for i.a. administration and lipid microspheres for i.p. or i.v. administration.
Shoji
F
F
Kobe-Gakuin Univ., Japan.
Masahiro
N
N
Yoshikazu
T
T
Masanori
F
F
D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000633:toxicity*; D002455:Cell Division / Q000187:drug effects; D002470:Cell Survival / Q000187:drug effects; D002945:Cisplatin / Q000008:administration & dosage / Q000627:therapeutic use / Q000633:toxicity; D003110:Colonic Neoplasms / Q000188:drug therapy* / Q000473:pathology; D004337:Drug Carriers; D005260:Female; D006367:HeLa Cells; D006801:Humans; D007269:Injections, Intra-Arterial; D007459:Iodized Oil; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D008545:Melanoma / Q000188:drug therapy* / Q000473:pathology; D051379:Mice; D008815:Mice, Inbred Strains; D008819:Mice, Nude; D008863:Microspheres; D011453:Prostaglandins / Q000008:administration & dosage* / Q000627:therapeutic use* / Q000633:toxicity; D011817:Rabbits; D051381:Rats; D017207:Rats, Sprague-Dawley; D014183:Transplantation, Heterologous; D014407:Tumor Cells, Cultured
D000970:Antineoplastic Agents; D004337:Drug Carriers; D011453:Prostaglandins; D007459:Iodized Oil; D002945:Cisplatin