title: Bromoacetamido-analogs of indomethacin and mefenamic acid affinity-label prostaglandin H2 synthase at two sites.
authors.affiliation: Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia 19104-6084, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Tang
authors.forename: L J
authors.initials: LJ
authors.lastname: Askonas
authors.forename: T M
authors.initials: TM
authors.lastname: Penning
mesh_terms: D000345:Affinity Labels; D000818:Animals; D001665:Binding Sites; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology*; D007213:Indomethacin / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D007700:Kinetics; D008297:Male; D008528:Mefenamic Acid / Q000378:metabolism / Q000494:pharmacology*; D008861:Microsomes / Q000201:enzymology; D010544:Peroxidases / Q000378:metabolism; D011451:Prostaglandin-Endoperoxide Synthases / Q000737:chemistry* / Q000378:metabolism*; D012669:Seminal Vesicles / Q000201:enzymology; D012756:Sheep; D062367:ortho-Aminobenzoates / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology*
chemical_list: C112081:4'-(bromoacetamido)-N-(2,3-dimethylphenyl)anthranilic acid; C112080:4'-(bromoacetamido)-benzyl-indomethacin; D000345:Affinity Labels; D016861:Cyclooxygenase Inhibitors; D062367:ortho-Aminobenzoates; D008528:Mefenamic Acid; D010544:Peroxidases; D011451:Prostaglandin-Endoperoxide Synthases; D007213:Indomethacin