title: Hematological parameters in Bufo arenarum injected with sublethal dose of lead acetate.
abstract: Lead has been recognized as a high risk toxic for most organisms including human. The effects of Pb in non-mammalian vertebrates are poorly known, particularly in anuran amphibians. The purpose of this study was to determine the effect of this metal on some hematological parameters of adult Bufo arenarum. It was found that all parameters remained unaltered within normal ranges, with the exception of reticulocyte counts which was significantly increased compared to the in controls (3.7% vs. 0.2%). It is suggested that the selective change found in reticulocyte count might be considered as an early response of a biomarker to sublethal exposition of Bufo arenarum to lead.
authors.affiliation: Cátedra de Fisiología Animal, Facultad de Ciencias Naturales, Universidad Nacional de La Plata (UNLP), Argentina.
authors.forename: S I
authors.initials: SI
authors.lastname: Perí
authors.forename: N E
authors.initials: NE
authors.lastname: Fink
authors.forename: A
authors.initials: A
authors.lastname: Salibián
mesh_terms: D000818:Animals; D002022:Bufo arenarum; D002452:Cell Count; D048429:Cell Size / Q000187:drug effects; D004906:Erythrocyte Count / Q000187:drug effects; D005260:Female; D006400:Hematocrit; D006454:Hemoglobins / Q000032:analysis; D007854:Lead / Q000633:toxicity*; D007958:Leukocyte Count / Q000187:drug effects; D009942:Organometallic Compounds / Q000008:administration & dosage / Q000633:toxicity*; D012156:Reticulocytes / Q000166:cytology / Q000187:drug effects*
chemical_list: D006454:Hemoglobins; D009942:Organometallic Compounds; D007854:Lead; C008261:lead acetate