Disseminated histoplasmosis presenting with cutaneous lesions in a patient with acquired immunodeficiency syndrome.
OBJECTIVE
Presentation of a case of disseminated histoplasmosis, observed in a non-endemic area, in which cutaneous lesions and fever were the dominant clinical signs of the infection.


METHODS
A 54-year-old homosexual man with acquired immunodeficiency syndrome (AIDS) related Kaposi's sarcoma presented with cutaneous lesions and fever due to disseminated histoplasmosis. The patient was successfully treated with itraconazole 200 mg/day. He died after 8 months from AIDS dementia complex: disseminated histoplasmosis relapse was not observed.


CONCLUSIONS
The case shows that infection with Histoplasma capsulatum must be considered by dermatologists in HIV/AIDS patients, even in non-endemic areas.
Angius
A G
AG
Institute of Dermatological Sciences of the University of Milan, IRCCS Ospedale Maggiore of Milan, Italy.
Viviani
M A
MA
Muratori
S
S
Cusini
M
M
Brignolo
L
L
Alessi
E
E
D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D000935:Antifungal Agents / Q000627:therapeutic use; D001707:Biopsy, Needle; D003881:Dermatomycoses / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D017809:Fatal Outcome; D006660:Histoplasmosis / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D018451:Homosexuality, Male; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D012514:Sarcoma, Kaposi / Q000175:diagnosis* / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology
D000935:Antifungal Agents; D017964:Itraconazole