title: Combined use of root conditioning, fibrin-fibronectin system and a collagen membrane to treat a localized gingival recession: a 10-case report.
abstract: The purpose of this research was to evaluate the effectiveness of combined root surface conditioning with tetracycline HCI, fibrin sealing system, guided tissue regeneration procedure and coronal sliding flap application in the treatment of localized gingival recessions. The present study was conducted on 10 patients with localized facial recessions of at least 3mm. A trapezium-shaped flap was elevated apically to the margin of the bone dehiscence and the root surface was thoroughly scaled by hand instruments and burs. Tetracycline HCI (pH 1.9) solution was then topically applied for 5 minutes and the root surface thoroughly rinsed with sterile saline. A collagen membrane was trimmed and shaped to cover the entire root surface and later removed and a fibrin sealing system injected onto the root surface. Immediately membrane was placed again on the root surface without applying any pressure. The flap was sutured in the coronal position to completely cover the root surface and membrane. Control group patients were treated with only coronal sliding flap operation. Sutures were removed 10 days after surgery. Patients were clinically reevaluated 6 months postoperatively. The mean amount of root surface coverage obtained was similar in the test and control groups (test = 71.7%; control = 68.55%) but the clinical attachment gain (test = 4.21mm; control = 2.86mm) and pocket depth variations (test = 1.14mm reduction; control = 0.07mm reduction) differed significantly (P < 0.001). This study found promising healing of localized gingival recessions to result from a combined use of tetracycline HCI root demineralization, fibrin sealing system application, guided tissue regeneration procedure and coronal sliding flap operation.
authors.affiliation: Gazi University, Faculty of Dentistry, Department of Periodontology, Ankara, Türkiye.
authors.forename: G
authors.initials: G
authors.lastname: Ozcan
authors.forename: B
authors.initials: B
authors.lastname: Kurtiş
authors.forename: K
authors.initials: K
authors.lastname: Baloş
mesh_terms: D000287:Administration, Topical; D000328:Adult; D003094:Collagen / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage*; D005889:Gingival Recession / Q000628:therapy*; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods* / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D013752:Tetracycline / Q000008:administration & dosage; D014016:Tissue Conditioning, Dental / Q000379:methods* / Q000706:statistics & numerical data; D014092:Tooth Root
chemical_list: D015718:Fibrin Tissue Adhesive; D008567:Membranes, Artificial; D003094:Collagen; D013752:Tetracycline