title: Amyotrophic lateral sclerosis: a lesson in deficiency diseases.
abstract: Amyotrophic lateral sclerosis (ALS) is an age-dependent degeneration of motor neurons in the central nervous system. ALS is not caused by faulty nutrition. Recent data suggest that ALS could be an oxidative neurotoxicity induced by a mutation in the SOD1 protein. This finding extends beyond the simple loss of an antioxidant enzyme.
authors.affiliation: Department of Biochemistry and Biophysics, Faculty of Nutrition, Texas A&M University, College Station 77843-2128, USA.
authors.forename: E D
authors.initials: ED
authors.lastname: Harris
mesh_terms: D000690:Amyotrophic Lateral Sclerosis / Q000201:enzymology / Q000235:genetics*; D000818:Animals; D006801:Humans; D013482:Superoxide Dismutase / Q000235:genetics* / Q000378:metabolism
chemical_list: D013482:Superoxide Dismutase