Successful treatment of gangrene in systemic necrotizing vasculitis with iloprost.
Systemic necrotizing vasculitis is uncommon in children and may be rarely associated with gangrene. We describe a 3-yr-old girl with parvovirus B19-induced necrotizing vasculitis whose digital gangrene was successfully treated with iloprost, a prostacyclin analogue.
Zulian
F
F
Department of Paediatrics, University of Padua, Italy.
Costantini
C
C
Montesco
M C
MC
Schiavon
F
F
Zacchello
F
F
D000914:Antibodies, Viral / Q000032:analysis; D002675:Child, Preschool; D005260:Female; D005385:Fingers / Q000473:pathology; D005734:Gangrene / Q000188:drug therapy* / Q000473:pathology / Q000821:virology; D006801:Humans; D016285:Iloprost / Q000627:therapeutic use*; D010322:Parvoviridae Infections / Q000150:complications / Q000188:drug therapy*; D016732:Parvovirus B19, Human / Q000276:immunology*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use*; D010488:Polyarteritis Nodosa / Q000188:drug therapy* / Q000473:pathology / Q000821:virology
D000914:Antibodies, Viral; D010975:Platelet Aggregation Inhibitors; D016285:Iloprost