title: Effects of aging on the functional outcome of coloanal anastomosis with colonic J-pouch.
abstract: BACKGROUND
  Many low rectal cancers can be treated radically by proctectomy with total mesorectal excision followed by colonic J-pouch anal anastomosis (CPAA). In elderly patients, the fear of poor function might reduce indications for CPAA in favor of abdomino-perineal excision with end stoma.
  
  
  METHODS
  Among 198 patients with CPAA operated on for low rectal cancer between 1984 and 1992, 20 patients over 75 years old were alive without recurrence at the time of telephone interview (July 1995). Minimal follow-up was 3 years (mean 8) for all patients. Their functional results were compared with those of 37 younger patients operated consecutively during the last 5 years of the study period.
  
  
  RESULTS
  The two groups were well matched for gender, tumor distance from the anal verge, histologic staging, and use of adjuvant radiotherapy. Follow-up was longer in the elderly group than in the young group (96 versus 63 months, respectively). The elderly group had a median of 1 bowel movement per day and the young group a median of 1.5 (P = 0.13). The presence of irregular intestinal transit was reported in 48% of the aged and in 35% of the young group (P = 0.6), but fragmented defecation was less frequent (25% versus 47%, respectively; P = 0.15). Urgency was noted, respectively, in 15% and 22% of elderly and young patients (P = 0.7) and constipation in 40% and 22% (P = 0.2). Incontinence for feces (15%) and for flatus (40%) in elderly were not significantly different from the younger group (14% and 46%, P = 1.0 and P = 0.8, respectively). Laxatives were used in 32% of elderly and 17% of young patients (P = 0.3).
  
  
  CONCLUSIONS
  Functional outcome may be good to excellent in elderly patients after CPAA and compares well with that obtained in younger patients. Constipation, however, may be more frequent in the elderly. Age is not a contraindication for CPAA if the sphincter tone is clinically normal.
authors.affiliation: Department of Alimentary Tract Surgery, Hospital and Faculty of Medicine Saint Antoine, University Pierre and Marie Curie, Paris, France.
authors.forename: N
authors.initials: N
authors.lastname: Dehni
authors.forename: D
authors.initials: D
authors.lastname: Schlegel
authors.forename: E
authors.initials: E
authors.lastname: Tiret
authors.forename: J D
authors.initials: JD
authors.lastname: Singland
authors.forename: M
authors.initials: M
authors.lastname: Guiguet
authors.forename: R
authors.initials: R
authors.lastname: Parc
mesh_terms: D000230:Adenocarcinoma / Q000601:surgery*; D000328:Adult; D000367:Age Factors; D000368:Aged; D001003:Anal Canal / Q000601:surgery; D000714:Anastomosis, Surgical; D003106:Colon / Q000601:surgery; D003672:Defecation; D005242:Fecal Incontinence / Q000209:etiology; D006801:Humans; D008875:Middle Aged; D011183:Postoperative Complications; D016737:Proctocolectomy, Restorative; D012004:Rectal Neoplasms / Q000601:surgery*; D016896:Treatment Outcome