title: [Gallbladder emptying evaluation in chronic calcifying pancreatitis, by means of a scintilographic study with Tc-99m DISIDA].
abstract: The aim of this study was to analyze the gallbladder motor function in chronic pancreatitis (CP) patients. Gallbladder emptying was evaluated in 11 patients, without and with addition of pancreatic extract and in ten controls. The results were compared and analyzed statistically. The ejection fraction (EF) of the gallbladder (GB) at 30, 45 and 60 minutes were calculated by using Tc-99m DISIDA scintigraphy. The EF of GB at 60 minutes was significantly higher in the controls when compared to patients, although the results between patients were similar without and with addition of pancreatic extract. The results suggest that the delay in the GB emptying does not depend on the eventual alteration in the intestinal phase of the vesicular stimulation, but it probably results from a mechanic factor, which depends on the chronic pathological process located in the head of the pancreas.
authors.affiliation: Grupo de Pâncreas e Vias Biliares da Disciplina de Gastroenterologia da Faculdade de Medicina da Universidade de São Paulo.
authors.forename: M R
authors.initials: MR
authors.lastname: Pedroso
authors.forename: R M
authors.initials: RM
authors.lastname: Cunha
authors.forename: D R
authors.initials: DR
authors.lastname: Guarita
authors.forename: C A
authors.initials: CA
authors.lastname: Buchpieguel
authors.forename: C B
authors.initials: CB
authors.lastname: Mott
authors.forename: A T
authors.initials: AT
authors.lastname: Laudanna
mesh_terms: D000328:Adult; D015992:Body Mass Index; D002114:Calcinosis / Q000503:physiopathology*; D002908:Chronic Disease; D005260:Female; D005704:Gallbladder / Q000000981:diagnostic imaging*; D016473:Gallbladder Emptying / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010184:Pancreatic Extracts; D010195:Pancreatitis / Q000503:physiopathology*; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D019785:Technetium Tc 99m Disofenin; D013997:Time Factors
chemical_list: D010184:Pancreatic Extracts; D019275:Radiopharmaceuticals; D019785:Technetium Tc 99m Disofenin