Down syndrome associated malformations.
This paper reports the associated malformations and the clinical findings that were observed in 417 cytogenetically confirmed Down Syndrome patients. Among them congenital heart defects have occurred more frequently [75; 17.98%] than osteoarticular malformations [23; 5.52]; eye anomalies [22; 5.27%]; and gastroenterological malformations [n 16; 3.84%]. With regard to prognosis and treatment appropriate counselling has been given to Down Syndrome patients and their families.
Rajangam
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Dept. of Anatomy, St. John's Medical College, Bangalore.
Hegde
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Thomas
I M
IM
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004065:Digestive System Abnormalities / Q000000981:diagnostic imaging / Q000453:epidemiology*; D004314:Down Syndrome / Q000000981:diagnostic imaging / Q000453:epidemiology*; D005124:Eye Abnormalities / Q000000981:diagnostic imaging / Q000453:epidemiology*; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009139:Musculoskeletal Abnormalities / Q000000981:diagnostic imaging / Q000453:epidemiology*; D011859:Radiography; D015619:Respiratory System Abnormalities / Q000000981:diagnostic imaging / Q000453:epidemiology*; D012189:Retrospective Studies; D017678:Sex Distribution