title: Successful perioperative management of congenital cystic adenomatoid malformation of the lung by high frequency oscillatory ventilation--report of two cases.
abstract: BACKGROUND
  Comparable to congenital diaphragmatic hernia, patients with congenital cystic adenomatoid malformation of the lung (CCAM) may develop life-threatening mediastinal shift and persistent pulmonary hypertension. In patients with diaphragmatic hernia, high frequency oscillatory ventilation (HFOV) has been shown to allow perioperative stabilisation.
  
  
  METHODS
  One term and one premature newborn of 30 gestational weeks with CCAM. Both patients developed massive mediastinal shift and intermittend pulmonary hypertension.
  
  
  METHODS
  Retrospective chart review.
  
  
  RESULTS
  In both patients perioperative stabilisation could be achieved by institution of HFOV. This allowed safe operation in the almost immobile surgical site and controlled transient episodes of pulmonary hypertension. The resection of the malformed lobe was performed under continued HFOV on the neonatal intensive care unit. Hereby, transport stress and additional hyperinflation by hand ventilation could be avoided.
  
  
  CONCLUSIONS
  Comparable with the situation when repairing a congenital diaphragmatic hernia, perioperative HFOV may be advantageous in managing severe CCAM.
authors.affiliation: Kinderklinik, Medizinische Einrichtungen der Westfälischen Wilhelms-Universität Münster.
authors.forename: R
authors.initials: R
authors.lastname: Rossi
authors.forename: T D
authors.initials: TD
authors.lastname: Tjan
authors.forename: R
authors.initials: R
authors.lastname: Hentschel
authors.forename: G
authors.initials: G
authors.lastname: Hülskamp
authors.forename: G
authors.initials: G
authors.lastname: Jorch
mesh_terms: D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006612:High-Frequency Ventilation; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015931:Intensive Care, Neonatal; D008297:Male; D010100:Oxygen / Q000097:blood; D019990:Perioperative Care; D010547:Persistent Fetal Circulation Syndrome / Q000000981:diagnostic imaging / Q000628:therapy; D011013:Pneumonectomy; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D010100:Oxygen