title: Ultrasonic tissue characterization for coronary care unit patients with acute myocardial infarction.
abstract: The ultrasonic integrated backscatter of myocardium changes in infarction and ischemia. On the third day after acute myocardial infarction, 30 patients underwent ultrasonic tissue characterization from the parasternal short-axis view. With a composite parameter, the phase-weighted variation, sensitivity, specificity, and accuracy for diagnosing multivessel coronary artery disease were 84.6%, 52.9% and 66.6%, respectively. Using 67 degrees as the cutoff value for the phase deviation of the backscatter power curve, the recanalization of the infarct-related artery could be detected with a positive predictive value of 77.7% and a negative predictive value of 66.6%. Ultrasonic tissue characterization is a feasible technique for detecting the multivessel coronary artery diseases and the recanalization of infarct-related artery for patients with acute myocardial infarction. The diminished cardiac cycle-dependent variation in integrated backscatter and increased phase deviation can differentiate patent coronary arteries from those coronary arteries with anatomically significant stenoses.
authors.affiliation: Department of Internal Medicine, National Taiwan University Hospital, Taipei, ROC.
authors.forename: L C
authors.initials: LC
authors.lastname: Lin
authors.forename: C C
authors.initials: CC
authors.lastname: Wu
authors.forename: Y L
authors.initials: YL
authors.lastname: Ho
authors.forename: C W
authors.initials: CW
authors.lastname: Lin
authors.forename: W J
authors.initials: WJ
authors.lastname: Chen
authors.forename: M F
authors.initials: MF
authors.lastname: Chen
authors.forename: C S
authors.initials: CS
authors.lastname: Liau
authors.forename: Y T
authors.initials: YT
authors.lastname: Lee
mesh_terms: D000368:Aged; D017023:Coronary Angiography; D004452:Echocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging*; D015424:Reperfusion; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity