title: New Hydroxylated Withanolides from Salpichroa origanifolia
abstract: From the leaves of Salpichroa origanifolia three new withanolides, (20S,22R,24S,25S,26R)-5alpha,6alpha:22,26:24,25-triepoxy-15,26-dihydroxy-17(13-->18)-abeo-ergosta-2,13,15,17-tetraen-1-one (salpichrolide G, 1), (20S,22R,24S,25R)-5alpha,6alpha:22,26-diepoxy-24,25,26-trihydroxy-17(13-->18)-abeo-ergosta-2,13,15,17-tetraen-1-one (salpichrolide H, 2), and (20S,22R,25S)-5alpha,6alpha:22,26-diepoxy-25,26-dihydroxy-17(13-->18)-abeo-ergosta-2,13,15,17,23-pentaen-1-one (salpichrolide I, 3), were isolated and characterized by spectroscopic methods and with the aid of molecular modeling. The latter two compounds were obtained as an epimeric mixture at C-26.
authors.affiliation: Departamento de Química Orgánica, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Pabellón 2, Ciudad Universitaria, 1428 Buenos Aires, Argentina, and Departamento de Química Orgánica and IMBIV, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Ap. Postal 4, Casilla 61, 5000 Córdoba, Argentina.
authors.initials: MC
authors.lastname: Tettamanzi
authors.initials: AS
authors.lastname: Veleiro
authors.initials: JC
authors.lastname: Oberti
authors.initials: G
authors.lastname: Burton