[Chronic obstructive pulmonary disease patients undergoing home oxygen therapy: a study of clinical parameters, nutritional status and ambulatory capacity].
OBJECTIVE
The aim of the study was to document the nutritional status and the calorie demands of patients suffering from severe chronic airflow obstruction (BPCO) who were on continuous domiciliary oxygen therapy (OCD) and to correlate this information with the clinical picture, the severity of the respiratory disease and the daily distance walked, this to be measured in a prospective manner.


METHODS
Fifty clinically stable patients with chronic airflow obstruction on continuous oxygen therapy for 33 months (range 4-106) in whom the following measures were made at home: pulmonary function, maximal static inspiratory and expiratory pressure (PIMAX and PEMAX), strength of hand, grip, the mean distance walked daily (wearing a pedometer for one week), body mass index (IMC), and the body composition by electrical bio-impedence and calorie requirements.


RESULTS
Thirty four per cent of patients presented with an excessive body mass (IMC > 27 kg/m2), 42 per cent had normal nutrition (IMC 20-27 kg/m2) and 24 per cent were malnourished (IMC < 20 kg/m2). Malnourished patients had, in a statistically significant manner, airflow obstruction of greater severity and a lower oxygen saturation and a PEMAX as well as a lower daily distance compared to over weight subjects. However, their net calorie requirements were markedly higher (39 +/- 5 Kcal/kg/j) compared to patients having normal weight (29 +/- 11 kcal/kg/j) or excess weight (25 +/- 8 kcal/kg/j). From the clinical standpoint no malnourished patient fulfilled the clinical criteria of chronic bronchitis. By contrast 61 per cent of subjects with normal nutrition and 94 per cent of subjects with excessive weight were chronic bronchitics.


CONCLUSIONS
In the group of patients with severe airflow obstruction on domiciliary oxygen, 25 per cent were malnourished and this was in spite of netly increased calorie consumption which is superior to their theoretical need. This suggests that the solution of increasing supplements to their dietary requirements would be a difficult to realise. These subjects presented also with a more marked ventilatory handicap and a clinical picture characterised by the absence of the classical signs of chronic bronchitis.
Frey
J G
JG
Centre Valaisan de Pneumologie, Montana, Suisse.
Rochat
T
T
Pichard
C
C
Dousse
N
N
Janssens
J P
JP
Tschopp
J M
JM
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001823:Body Composition; D015992:Body Mass Index; D001835:Body Weight; D001991:Bronchitis / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy; D002908:Chronic Disease; D017097:Electric Impedance; D004734:Energy Metabolism; D005260:Female; D005500:Follow-Up Studies; D018737:Hand Strength / Q000502:physiology; D006699:Home Care Services; D006801:Humans; D007320:Inspiratory Capacity / Q000502:physiology; D008168:Lung / Q000503:physiopathology; D008173:Lung Diseases, Obstructive / Q000097:blood / Q000378:metabolism / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009748:Nutrition Disorders / Q000097:blood / Q000503:physiopathology; D009752:Nutritional Status; D010100:Oxygen / Q000097:blood; D010102:Oxygen Inhalation Therapy; D010366:Peak Expiratory Flow Rate / Q000502:physiology; D011446:Prospective Studies; D012720:Severity of Illness Index; D016138:Walking / Q000502:physiology*
D010100:Oxygen