Synthesis of new immunogens for estrone and estradiol-17 beta and antisera evaluation.
Syntheses of the 6 alpha-O-carboxymethyl ether derivatives of estrone and estradiol-17 beta and the preparation of their bovine serum albumin conjugates are described. The generation and evaluation of antisera produced from these conjugates is discussed.
Rao
P N
PN
Department of Organic Chemistry, Southwest Foundation for Biomedical Research, San Antonio, Texas 78245-0549, USA.
Wang
Z
Z
Cessac
J W
JW
Moore
P H
PH
D000818:Animals; D004958:Estradiol / Q000737:chemistry / Q000276:immunology*; D004970:Estrone / Q000737:chemistry / Q000276:immunology*; D005069:Evaluation Studies as Topic; D007106:Immune Sera; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D015394:Molecular Structure; D011817:Rabbits; D012710:Serum Albumin, Bovine / Q000737:chemistry; D014614:Vaccines, Synthetic / Q000737:chemistry*
D007106:Immune Sera; D014614:Vaccines, Synthetic; D012710:Serum Albumin, Bovine; D004970:Estrone; D004958:Estradiol