An investigation of the effects of the local use of 1:25 dihydroxycholecalciferol (1:25 D) on tension sites during experimental tooth movement in rats.
The aim of this work was to investigate the local effects of 1:25 dihydroxychole-calciferol, one of the most potent osteoclastic activity stimulants. Tests were conducted on 32 Wistar albino rats divided into 3 groups: an experimental (appliance + drug, n = 11), control (appliance only, n = 11) and a no therapy group (n = 10) which was used for purposes of interpreting histological findings in the others. A significantly higher area of unilateral apposition, relative to the control group, was observed in the experimental group local to the area of administration of the 1:25 D.
Baran
S
S
Faculty of Dentistry, Dicle University, Diyarbakir, Türkiye.
Hamamci
O
O
Akalar
M
M
D000287:Administration, Topical; D000818:Animals; D001862:Bone Resorption / Q000139:chemically induced / Q000473:pathology; D002117:Calcitriol / Q000008:administration & dosage* / Q000494:pharmacology; D008437:Maxilla / Q000187:drug effects / Q000473:pathology; D009967:Orthodontic Appliances; D051381:Rats; D017208:Rats, Wistar; D013268:Stimulation, Chemical; D013997:Time Factors; D014087:Tooth Movement Techniques / Q000295:instrumentation / Q000379:methods*
D002117:Calcitriol