title: Studies on the Synthesis of Elegan-Type Linear Diterpenes: The Efficient Total Syntheses of Eleganolone, Eleganolone Acetate, Elegandiol, Eleganonal, and Epoxyeleganolone
abstract: The first total syntheses of five elegan-type linear diterpenes-eleganolone (1), eleganolone acetate (2), elegandiol (3), eleganonal (4), and epoxyeleganolone (5)-were accomplished starting from (E,E)-farnesol (6) via four to six steps, successively, with high overall yield. The key step was the alkylation reaction of silyl cyanide with allylic iodide.
authors.affiliation: National Laboratory of Applied Organic Chemistry and Institute of Organic Chemistry, Lanzhou University, Lanzhou 730000, People's Republic of China.
authors.initials: J
authors.lastname: Li
authors.initials: J
authors.lastname: Lan
authors.initials: Z
authors.lastname: Liu
authors.initials: Y
authors.lastname: Li