Altered secretory responsiveness of BRIN-BD11 cells cultured under hyperglycaemic conditions is not readily reversed by subsequent culture in lower glucose concentrations.
Wilson
A M
AM
Diabetes Research Group, School of Biomedical Sciences, University of Ulster, N. Ireland, United Kingdom.
Barnett
C R
CR
Flatt
P R
PR
D000818:Animals; D002459:Cell Fusion; D002460:Cell Line; D006224:Cricetinae; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D004305:Dose-Response Relationship, Drug; D005947:Glucose / Q000494:pharmacology*; D006943:Hyperglycemia; D007328:Insulin / Q000378:metabolism*; D000078790:Insulin Secretion; D007515:Islets of Langerhans / Q000187:drug effects / Q000378:metabolism*; D008647:Mesocricetus; D008954:Models, Biological; D051381:Rats
D007328:Insulin; D005947:Glucose