Gametogenesis: keeping the male element under control.
Caenorhabditis elegans hermaphrodites switch from making sperm to oocytes. This switch involves repression of fem-3 mRNA, mediated by a protein that binds RNA through a conserved motif; a similar motif mediates RNA binding by the Drosophila pattern-regulatory protein Pumilio.
Kuwabara
P E
PE
Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK. pek@mrc-lmb.cam.ac.uk
D000818:Animals; D017173:Caenorhabditis elegans / Q000235:genetics / Q000502:physiology*; D029742:Caenorhabditis elegans Proteins; D012734:Disorders of Sex Development / Q000235:genetics; D004330:Drosophila / Q000235:genetics / Q000502:physiology; D029721:Drosophila Proteins; D005718:Gametogenesis / Q000235:genetics*; D015801:Helminth Proteins / Q000235:genetics / Q000378:metabolism; D019476:Insect Proteins / Q000235:genetics; D008297:Male; D018510:RNA, Helminth / Q000235:genetics / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics* / Q000378:metabolism; D016601:RNA-Binding Proteins / Q000378:metabolism; D019849:Sex Determination Processes
D029742:Caenorhabditis elegans Proteins; D029721:Drosophila Proteins; D015801:Helminth Proteins; D019476:Insect Proteins; D018510:RNA, Helminth; D012333:RNA, Messenger; D016601:RNA-Binding Proteins; C075059:fem-3 protein, C elegans; C109286:fem-3-binding protein, C elegans; C074333:pum protein, Drosophila