Remission of infantile systemic lupus erythematosus with intravenous cyclophosphamide.
We report an 8-month-old boy with systemic lupus erythematosus and World Health Organization class IV lupus nephritis who has gone into complete clinical and serological remission with pulse i.v. cyclophosphamide therapy. To our knowledge this is the first case of pulse i.v. cyclophosphamide therapy in infantile systemic lupus erythematosus resulting in long-term remission.
Saberi
M S
MS
Department of Pediatrics, Saint John Hospital and Medical Center, Detroit, Michigan, USA.
Jones
B A
BA
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D018906:Antineoplastic Agents, Alkylating / Q000008:administration & dosage / Q000627:therapeutic use*; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D007275:Injections, Intravenous; D007678:Kidney Glomerulus / Q000473:pathology; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D011241:Prednisone / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D018906:Antineoplastic Agents, Alkylating; D003520:Cyclophosphamide; D011241:Prednisone