[The 5 factor model of childhood schizophrenia].
Forty-four first-admission patients with childhood-onset schizophrenia (age at onset < or = 14 years) were examined retrospectively for 30 clinical symptoms using the Positive and Negative Syndrome Scale (PANSS; 15). A principal component analysis with varimax rotation was applied to the full item set of this scale and revealed five orthogonal independent symptom groups: cognition affect, social withdrawal, anti-social behavior, excitement, and reality distortion. In order to validate these psychopathological dimensions we analyzed the relation between the five factor scores and outcome variables (Disability Assessment Schedule, DAS-M; 13) several years after onset: Social withdrawal was correlated with poor outcome; reality distortion was related to good outcome (P < 0.01). A multivariate ANOVA identified group differences in the anti-social behavior factor between acute and insidious onset of illness and between boys and girls; patients with an acute onset scored significantly higher on the excitement factor than those with an insidious onset (P < 0.05). According to our results more than two dimensions are necessary to describe the psychopathology of childhood-onset schizophrenia, similar to adolescent- and adult-onset schizophrenia.
Klapal
M
M
Klinik für Kinder- und Jugendpsychiatrie, Rheinische Landes- und Hochschulklinik, Essen.
Eggers
C
C
Bunk
D
D
Koriath
H
H
D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D010343:Patient Admission; D011569:Psychiatric Status Rating Scales / Q000706:statistics & numerical data*; D011594:Psychometrics; D011936:Reality Testing; D012189:Retrospective Studies; D012561:Schizophrenia, Childhood / Q000145:classification / Q000175:diagnosis* / Q000523:psychology; D012569:Schizotypal Personality Disorder / Q000145:classification / Q000175:diagnosis* / Q000523:psychology; D012919:Social Behavior; D012934:Social Isolation