title: The mini bottle brush--a new fastening device in cancellous bone.
abstract: A new design for bone implants, the bottle brush, was recently presented in a pilot study on marrow cavities in the femur of rabbits. In this study, the concept is further evaluated on a mini bottle brush. The fixture, 5 x 7 mm, with an implant shaft made of CP-titanium and bristles of nylon coated with sputtered titanium, was inserted into the cancellous bone of the medial femoral condyle in 15 adult rabbits. The titanium fixture was compared with a similar brush without the titanium sputtered surface. The animals were sacrificed after 4 months and the quantity and quality of bone integration were evaluated with pull-out tests and histological examination. In both parameters, the values were significantly higher for the titanium-sputtered brushes, with removal forces similar to titanium cylinders of the same size and with a bone-to-metal contact area of about 50%.
authors.affiliation: Department of Plastic Surgery, Hand Surgery and Burns, University Hospital, Linköping, Sweden.
authors.forename: L
authors.initials: L
authors.lastname: Krysander
authors.forename: S
authors.initials: S
authors.lastname: Hellem
authors.forename: A
authors.initials: A
authors.lastname: Berggren
authors.forename: B
authors.initials: B
authors.lastname: Klinge
mesh_terms: D000818:Animals; D001706:Biopsy; D001842:Bone and Bones / Q000601:surgery*; D005069:Evaluation Studies as Topic; D005269:Femur / Q000473:pathology; D008422:Materials Testing; D009757:Nylons; D016348:Osseointegration / Q000502:physiology; D019736:Prostheses and Implants; D011474:Prosthesis Design; D019919:Prosthesis Implantation / Q000379:methods; D011817:Rabbits; D013314:Stress, Mechanical; D014025:Titanium
chemical_list: D009757:Nylons; D014025:Titanium