Evaluation of structurally different carotenoids in Escherichia coli transformants as protectants against UV-B radiation.
Escherichia coli cells transformed with several carotenogenic genes to mediate the formation of zeta-carotene, neurosporene, lycopene, beta-carotene, and zeaxanthin were exposed to UV-B radiation. Short-term kinetics revealed that endogenous levels of neurosporene and beta-carotene protected E. coli against irradiation with UV-B. Zeaxanthin protected against only the photosensitized UV-B treatment. All other carotenoids were ineffective.
Sandmann
G
G
Botanisches Institut, Fachbereich Biologie, J. W. Goethe Universität, Frankfurt, Germany. Sandmann@em.uni-frankfurt.d400.de
Kuhn
S
S
Böger
P
P
D002338:Carotenoids / Q000235:genetics / Q000502:physiology*; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics; D011837:Radiation-Protective Agents; D014169:Transformation, Bacterial; D014466:Ultraviolet Rays
D011837:Radiation-Protective Agents; D002338:Carotenoids