Isolation of novel human cDNA (hGMF-gamma) homologous to Glia Maturation Factor-beta gene.
A novel full-length human cDNA homologous to Glia Maturation Factor-beta (GMF-beta) gene was isolated. Sequence analysis of the entire cDNA revealed an open reading frame of 426 nucleotides with a deduced protein sequence of 142 amino acid residues. The deduced amino acid sequences of its putative product is highly homologous to human GMF-beta (82% identity) and named for GMF-gamma. Northern blot analysis indicated that a message of 0.9 kb long, but not 4.1 kb of GMF-beta, is predominantly expressed in human lung, heart, and placenta.
Asai
K
K
Department of Bioregulation Research, Nagoya City University Medical School, Japan. kiyoasai@med.nagoya-cu.ac.jp
Fujita
K
K
Yamamoto
M
M
Hotta
T
T
Morikawa
M
M
Kokubo
M
M
Moriyama
A
A
Kato
T
T
D000595:Amino Acid Sequence; D001483:Base Sequence; D015152:Blotting, Northern; D001921:Brain; D003001:Cloning, Molecular; D018076:DNA, Complementary / Q000302:isolation & purification*; D005333:Fetus; D020904:Glia Maturation Factor; D006801:Humans; D008969:Molecular Sequence Data; D009419:Nerve Tissue Proteins / Q000235:genetics* / Q000302:isolation & purification; D009928:Organ Specificity / Q000235:genetics; D017386:Sequence Homology, Amino Acid
D018076:DNA, Complementary; D020904:Glia Maturation Factor; D009419:Nerve Tissue Proteins