Dynamic complexation of solutes in capillary electrophoresis.
The analyte migration behavior in any chemical separation system can be described using a single equation that unifies all areas of separation science. This equation can be used in capillary electrophoresis (CE) to design separation systems, and to study interactions between analytes and additives. By using individual capacity factors for each analyte species present in the system, and with the knowledge of the characteristics of each interaction, one can predict the analyte migration behavior in complicated CE systems, including systems with multiple 1:1 interactions and/or higher order interactions.
Bowser
M T
MT
Department of Chemistry, University of British Columbia, Vancouver, Canada.
Chen
D D
DD
D001665:Binding Sites; D019075:Electrophoresis, Capillary / Q000379:methods* / Q000706:statistics & numerical data; D007700:Kinetics; D008962:Models, Theoretical; D012996:Solutions
D012996:Solutions