Separation of indenestrol A and B isomers and enantiomers by high-performance liquid chromatography.
High-performance liquid chromatography (HPLC) methods have been developed for the separation of substituted indenestrol A and B isomers on different columns. The isomers were separated by normal-phase liquid chromatography with a silica gel column. Enantiomers of these compounds were separated by chiral HPLC and the most successful separations were achieved with a Chiralcel OJ column.
Sadler
B R
BR
Laboratory of Reproductive and Developmental Toxicology, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709, USA.
Chae
K
K
Ishaq
K S
KS
Korach
K S
KS
D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D004968:Estrogens, Non-Steroidal / Q000302:isolation & purification*; D007192:Indenes / Q000302:isolation & purification*; D007536:Isomerism
D004968:Estrogens, Non-Steroidal; D007192:Indenes; C047437:indenestrol