[Malaria therapy; ups and downs, how much longer?].
The natural products quinine and artemisinine have been effective antimalarials for centuries. Most synthetic antimalarials were developed because of pressure of war; against all some degree of resistance has developed. The newer drugs are too expensive for large-scale use. Development of new antimalarials is financially too risky for the pharmaceutical industry. Co-operation among industries, research institutes, governments and international organizations is coming off the ground. Dutch researchers should contribute to international malaria research for humanitarian reasons and out of self-interest, for the benefit of public health.
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Afd. Inwendige Geneeskunde, onderafd. Infectieziekten, Tropische Geneeskunde en Aids, Universiteit van Amsterdam/Academisch Medisch Centrum.
D000962:Antimalarials / Q000138:chemical synthesis / Q000627:therapeutic use*; D004351:Drug Resistance; D006801:Humans; D007391:International Cooperation; D008288:Malaria / Q000188:drug therapy*
D000962:Antimalarials