KNI-577, a potent small-sized HIV protease inhibitor based on the dipeptide containing the hydroxymethylcarbonyl isostere as an ideal transition-state mimic.
Kiso
Y
Y
Department of Medicinal Chemistry, Kyoto Pharmaceutical University, Japan.
Yamaguchi
S
S
Matsumoto
H
H
Mimoto
T
T
Kato
R
R
Nojima
S
S
Takaku
H
H
Fukazawa
T
T
Kimura
T
T
Akaji
K
K
D004151:Dipeptides / Q000494:pharmacology*; D017320:HIV Protease Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D015497:HIV-1; D008970:Molecular Weight
D004151:Dipeptides; D017320:HIV Protease Inhibitors; C112011:KNI 577