title: FT-IR spectroscopy as an emerging method for rapid characterization of microorganisms.
abstract: Statistical methods such as principal component analysis and cluster analysis were used to analyze ATR-FT-IR spectra obtained from bacterial whole cells. Both methods gave satisfactory results and are conclusive in showing that they can discriminate and classify bacterial strains of clinical origin exhibiting different resistance mechanisms. This approach places FT-IR spectroscopy at the forefront of those new potential techniques that could be used in the rapid screening of microorganisms.
authors.affiliation: Laboratoire de Spectroscopie Biomoléculaire, IFR 53, UFR de Pharmacie, Université de Reims Champagne-Ardenne, France.
authors.forename: G D
authors.initials: GD
authors.lastname: Sockalingum
authors.forename: W
authors.initials: W
authors.lastname: Bouhedja
authors.forename: P
authors.initials: P
authors.lastname: Pina
authors.forename: P
authors.initials: P
authors.lastname: Allouch
authors.forename: C
authors.initials: C
authors.lastname: Bloy
authors.forename: M
authors.initials: M
authors.lastname: Manfait
mesh_terms: D004926:Escherichia coli / Q000145:classification* / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D011550:Pseudomonas aeruginosa / Q000145:classification* / Q000187:drug effects; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods*; D013997:Time Factors; D018440:beta-Lactam Resistance