title: [Diabetic gastroparesis: is tube feeding an alternative?].
abstract: A woman aged 26 with long-standing insulin-dependent diabetes mellitus displayed recurrent periods of nausea, vomiting, abnormal blood sugar levels, weight loss and poor physical condition in spite of a diet and use of propulsive agents. Scintigraphy revealed decelerated gastric evacuation for solid and liquid nutrients. The patient recovered after insertion of a percutaneous endoscopic gastrostomy (PEG) catheter. Diabetic gastroparesis is associated with a vicious circle in which delayed gastric emptying leads to poor glucose regulation with frequent hyperglycaemia, which in its turn adversely affects gastric emptying. Treatment should be aimed at improvement of the gastric motility (for instance by propulsive agents), more accurate glucose regulation and nutritional counselling. If this fails to produce improvement, tube feeding via a permanent nasoduodenal tube or via a PEG catheter constitutes an acceptable alternative for oral nutrition.
authors.affiliation: Afd. Maag. Academisch Ziekenhuis, Leiden.
authors.forename: U
authors.initials: U
authors.lastname: Schlüter
authors.forename: J W
authors.initials: JW
authors.lastname: Smit
authors.forename: A
authors.initials: A
authors.lastname: Wipkink-Bakker
authors.forename: A A
authors.initials: AA
authors.lastname: Masclee
mesh_terms: D000328:Adult; D001786:Blood Glucose; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000150:complications*; D004750:Enteral Nutrition; D005260:Female; D005746:Gastric Emptying; D018589:Gastroparesis / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D005774:Gastrostomy; D006801:Humans
chemical_list: D001786:Blood Glucose