[Transplantation of fetal tissues in otorhinolaryngology: current status and prospects for the future].
Insufficient efficacy of treatment of neurosensory hypoacusis makes investigators search for new methods. Transplantation of fetal tissue taken from healthy embryos of gestation stage II tried in various fields of medicine, such as neurology, endocrinology, surgery, etc., was also tested in management of various forms of neurosensory hypoacusis. Endonasal, endaural, endolumbal and intracochlear methods of the transplantation are detailed. Results of combined dynamic audiological control of these patients including tonal threshold audiometry in extended frequency range are presented. A 1-year follow-up provided evidence in favour of endolumbal and intracochlear transplantation. Further investigations are needed.
Magomedov
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D000328:Adult; D001301:Audiometry, Pure-Tone; D016380:Brain Tissue Transplantation; D002530:Cerebellopontine Angle / Q000196:embryology / Q000601:surgery; D002908:Chronic Disease; D003051:Cochlea / Q000196:embryology / Q000637:transplantation; D005260:Female; D016332:Fetal Tissue Transplantation / Q000379:methods / Q000639:trends; D005500:Follow-Up Studies; D006319:Hearing Loss, Sensorineural / Q000209:etiology / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010036:Otolaryngology / Q000379:methods*; D012189:Retrospective Studies; D013702:Temporal Lobe / Q000196:embryology / Q000637:transplantation; D000159:Vestibulocochlear Nerve / Q000196:embryology / Q000637:transplantation