Induction of glutathione S-transferase activity in Triatoma infestans.
Several synthetic pesticides and allelochemicals used to treat Triatoma infestans adults by topic application showed some degree of cytosolic glutathione S-transferase (GST) induction. General inducers of detoxication systems such as phenobarbital and 3-methylcholantrene topically applied on T. infestans resulted in no GST induction. Meanwhile, general insecticide synergist such as piperonyl butoxide (160 micrograms/insect) increased the GST-activity in the range of 120-140%. Insects injected with reduced glutathione (300 mg/insect) presented at the forth day elevated GST activity.
Sívori
J L
JL
Centro de Investigaciones de Plagas e Insecticidas-CIPEIN-(CITEFA-CONICET), Buenos Aires, Argentina.
Casabé
N
N
Zerba
E N
EN
Wood
E J
EJ
D000818:Animals; D004790:Enzyme Induction; D005982:Glutathione Transferase / Q000096:biosynthesis* / Q000187:drug effects*; D008297:Male; D013056:Spectrophotometry, Ultraviolet; D014224:Triatoma / Q000187:drug effects / Q000201:enzymology*
D005982:Glutathione Transferase