title: First COMT inhibitor approved for Parkinson's disease.
mesh_terms: D000978:Antiparkinson Agents / Q000627:therapeutic use*; D001577:Benzophenones / Q000627:therapeutic use*; D065098:Catechol O-Methyltransferase Inhibitors; D017277:Drug Approval; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D006801:Humans; D009596:Nitrophenols; D010300:Parkinson Disease / Q000188:drug therapy*; D000077867:Tolcapone; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D000978:Antiparkinson Agents; D001577:Benzophenones; D065098:Catechol O-Methyltransferase Inhibitors; D004791:Enzyme Inhibitors; D009596:Nitrophenols; D000077867:Tolcapone