Risperidone in the treatment of delusions of infestation.
OBJECTIVE
The aim of this study is to describe the efficacy and safety of risperidone, in the treatment of delusions of infestation.


METHODS
The authors present a three-case series in which risperidone was used to treat delusions of infestation.


RESULTS
All three patients responded to risperidone and experienced no extrapyramidal side effects. Two of our patients had failed treatment with haloperidol and another had failed treatment with pimozide.


CONCLUSIONS
Risperidone was an effective and safe treatment in three cases of delusions of infestation. It is possible that 5-HT2 antagonism is essential for therapeutic benefit in this condition.
De León
O A
OA
Department of Psychiatry, University of Illinois at Chicago 60612, USA.
Furmaga
K M
KM
Canterbury
A L
AL
Bailey
L G
LG
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D003702:Delusions / Q000188:drug therapy* / Q000523:psychology; D003704:Dementia / Q000188:drug therapy / Q000523:psychology; D004478:Ectoparasitic Infestations / Q000523:psychology*; D005260:Female; D006212:Hallucinations / Q000188:drug therapy / Q000523:psychology; D006801:Humans; D008297:Male; D019965:Neurocognitive Disorders / Q000188:drug therapy / Q000523:psychology; D012008:Recurrence; D018967:Risperidone / Q000009:adverse effects / Q000627:therapeutic use*
D014150:Antipsychotic Agents; D018967:Risperidone