title: Treatment of a local recurrence of a carcinoid tumor of the middle ear by extended subtotal petrosectomy.
abstract: A recurrence of a primary carcinoid tumor of the middle ear 15 years after radical tympanomastoidectomy is reported. An extended subtotal petrosectomy using a craniocervical approach with temporary infracondylar mandibulotomy was performed, since imaging studies demonstrated an extensive tumor with a close relationship to the tegmen tympani, facial nerve, and ascending and horizontal portions of the carotid canal. The tumor was metabolically inactive. Histopathological examination showed a solid, trabecular tumor that was positive for pancytokeratin Lu5, neuron-specific enolase, pancreatic intestinal polypeptide and glucagon. Neuroendocrine-granules were demonstrable under electron microscopy. This case is reported to show that primary middle-ear carcinoid tumors can recur years after radical tympanomastoidectomy.
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, University of Vienna, Austria.
authors.forename: B
authors.initials: B
authors.lastname: Knerer
authors.forename: C
authors.initials: C
authors.lastname: Matula
authors.forename: S
authors.initials: S
authors.lastname: Youssefzadeh
authors.forename: W
authors.initials: W
authors.lastname: Ulrich
authors.forename: H
authors.initials: H
authors.lastname: Swoboda
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D002276:Carcinoid Tumor / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D004428:Ear Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D004432:Ear, Middle / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D010579:Petrous Bone / Q000473:pathology / Q000601:surgery*; D012086:Reoperation
chemical_list: D014408:Biomarkers, Tumor