Experimental models of colorectal cancer.
OBJECTIVE
A review of in vivo and in vitro models of colorectal cancer is presented.


METHODS
A retrospective literature review was performed with reference to CD-ROM Medline and Index Medicus.


RESULTS
A comparison of the advantages and disadvantages of the models is presented in addition to a summary of individual model methodology and applications.


CONCLUSIONS
Such models are a useful adjunct for surgical research in colorectal oncology.
Banerjee
A
A
Department of Surgery, Royal Halifax Infirmary, and University of Leeds Medical School, United Kingdom.
Quirke
P
P
D000818:Animals; D002273:Carcinogens; D002478:Cells, Cultured; D003043:Cocarcinogenesis; D015179:Colorectal Neoplasms / Q000139:chemically induced / Q000209:etiology; D006801:Humans; D066298:In Vitro Techniques; D008954:Models, Biological; D008957:Models, Genetic; D009362:Neoplasm Metastasis; D013514:Surgical Procedures, Operative; D014947:Wounds and Injuries / Q000150:complications
D002273:Carcinogens