Children who can't smell the coffee: isolated congenital anosmia.
Two children with isolated congenital anosmia, a rare syndrome of deficient restricted neuronal migration, are presented with early diagnosis confirmed by standardized smell testing and detailed neuroimaging studies. Recognition of this disorder and its spectrum of presentations provides important insights into the molecular mechanisms underlying the development of the olfactory system.
Assouline
S
S
Division of Pediatric Neurology, Montreal Children's Hospital, Quebec, Canada.
Shevell
M I
MI
Zatorre
R J
RJ
Jones-Gotman
M
M
Schloss
M D
MD
Oudjhane
K
K
D000293:Adolescent; D003069:Coffee; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009297:Nasal Mucosa / Q000502:physiology; D000857:Olfaction Disorders / Q000151:congenital*; D009830:Olfactory Bulb / Q000000981:diagnostic imaging* / Q000473:pathology; D009833:Olfactory Pathways / Q000254:growth & development*; D011877:Radionuclide Imaging; D012903:Smell; D013577:Syndrome
D003069:Coffee