title: Interhemispheric memory transfer in the intracarotid amobarbital procedure.
abstract: The authors examined interhemispheric memory transfer in 32 patients with lateralized temporal lobe complex partial epilepsy (15 right onsets, 17 left onsets). Visually presented verbal, nonverbal, and two types of dually encodable stimuli were displayed during amobarbital anesthesia, and recognition memory was tested with verbal and nonverbal (pointing) response modalities. No relationship was found between the material specificity of stimuli and response modality. The only significant findings were for poorer recognition memory after injection of the hemisphere contralateral to the seizure focus. Visual information presented predominantly to one hemisphere during anesthesia is available to the other hemisphere for recognition memory on clearing.
authors.affiliation: Department of Neurology, Hospital for Joint Disease, New York, New York.
authors.forename: K
authors.initials: K
authors.lastname: Perrine
authors.forename: N
authors.initials: N
authors.lastname: Donofrio
authors.forename: O
authors.initials: O
authors.lastname: Devinsky
authors.forename: J
authors.initials: J
authors.lastname: Gershengorn
authors.forename: D J
authors.initials: DJ
authors.lastname: Luciano
authors.forename: P K
authors.initials: PK
authors.lastname: Nelson
mesh_terms: D000328:Adult; D000654:Amobarbital; D002343:Carotid Artery, Internal; D002540:Cerebral Cortex / Q000187:drug effects / Q000502:physiology*; D004292:Dominance, Cerebral / Q000502:physiology; D004833:Epilepsy, Temporal Lobe / Q000503:physiopathology*; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives; D007269:Injections, Intra-Arterial; D008297:Male; D008568:Memory / Q000187:drug effects / Q000502:physiology*; D008569:Memory Disorders / Q000139:chemically induced; D009434:Neural Pathways / Q000502:physiology; D009483:Neuropsychological Tests; D010364:Pattern Recognition, Visual / Q000502:physiology; D014163:Transfer, Psychology / Q000502:physiology*; D014705:Verbal Behavior / Q000502:physiology
chemical_list: D006993:Hypnotics and Sedatives; D000654:Amobarbital