Enantioselective Total Syntheses of (-)-7betaH-Eudesmane-4alpha,11-diol and (+)-ent-7betaH-Eudesmane-4alpha,11-diol
The syntheses of (-)-7betaH-eudesmane-4alpha,11-diol (2) and (+)-ent-7betaH-eudesmane-4alpha,11-diol (ent-2) were carried out starting from (-)- and (+)-dihydrocarvones. As a result, the structure, including absolute configuration, of the naturally occurring eudesmane-4,11-diol isolated from Pluchea arguta was determined to be (+)-ent-7betaH-eudesmane-4alpha,11-diol (ent-2).
Shimoma
F
Department of Applied Chemistry, Faculty of Engineering, Niigata University, Ikarashi 2-8050, Niigata, 950-21, Japan, and Graduate School of Science and Technology, Niigata University, Ikarashi 2-8050, Niigata 950-21, Japan.
Kondo
H
Yuuya
S
Suzuki
T
Hagiwara
H
Ando
M