title: Alterations of substance P immunoreactivity in lumbar and thoracic segments of rat spinal cord in ultraviolet irradiation induced hyperalgesia of the hindpaw.
abstract: Substance P immunostaining was quantified on sections from the 4th-5th lumbar and midthoracic spinal segments of rats at the peak of hyperalgesia following ultraviolet irradiation-induced inflammation of one hindpaw. The area of the immunostaining in the lumbar dorsal horn was significantly decreased on both sides by 50%, while in the thoracic spinal cord, it was increased by 18% on the contralateral and stayed unchanged on the ipsilateral side.
authors.affiliation: Department of Anatomy, Histology and Embryology, University Medical School, Debrecen H-4012, Hungary. ep7u@udcf.gla.ac.uk
authors.forename: E
authors.initials: E
authors.lastname: Polgár
authors.forename: P
authors.initials: P
authors.lastname: Szûcs
authors.forename: L
authors.initials: L
authors.lastname: Urbán
authors.forename: I
authors.initials: I
authors.lastname: Nagy
mesh_terms: D000818:Animals; D006614:Hindlimb / Q000528:radiation effects*; D006930:Hyperalgesia / Q000209:etiology* / Q000378:metabolism; D007158:Immunologic Techniques; D008161:Lumbosacral Region; D011833:Radiation Injuries, Experimental / Q000150:complications*; D051381:Rats; D011921:Rats, Inbred WKY; D013116:Spinal Cord / Q000378:metabolism*; D013373:Substance P / Q000378:metabolism*; D013909:Thorax; D014466:Ultraviolet Rays
chemical_list: D013373:Substance P