Ultrarapid metabolism of clomipramine in a therapy-resistant depressive patient, as confirmed by CYP2 D6 genotyping.
Baumann
P
P
Broly
F
F
Kosel
M
M
Eap
C B
CB
D000929:Antidepressive Agents, Tricyclic / Q000493:pharmacokinetics* / Q000627:therapeutic use; D002997:Clomipramine / Q000493:pharmacokinetics* / Q000627:therapeutic use; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics* / Q000378:metabolism*; D003866:Depressive Disorder / Q000188:drug therapy / Q000235:genetics* / Q000378:metabolism*; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged
D000929:Antidepressive Agents, Tricyclic; D019389:Cytochrome P-450 CYP2D6; D002997:Clomipramine