title: Monitoring oxygen partial pressure in tissue using microdialysis sampling and membrane coated oxygen sensors.
abstract: The use of microdialysis sampling coupled to oxygen sensors for monitoring oxygen tension in the tissue of animals was examined. The response time of the microdialysis sampling system was not different than oxygen sensors implanted directly in the tissue. The microdialysis system could be calibrated in vivo using the no-net-flux calibration method while directly implanted oxygen sensors had to rely on in vitro calibration. No difference was found in the oxygen tensions determined in vivo between microdialysis sampling and direct sensor implantations.
authors.affiliation: Department of Chemistry, University of Kansas, Lawrence 66045, USA.
authors.forename: X Z
authors.initials: XZ
authors.lastname: Liang
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: C E
authors.initials: CE
authors.lastname: Lunte
mesh_terms: D000818:Animals; D015374:Biosensing Techniques; D001785:Blood Gas Monitoring, Transcutaneous / Q000379:methods*; D004566:Electrodes; D008297:Male; D008567:Membranes, Artificial; D017551:Microdialysis; D051381:Rats
chemical_list: D008567:Membranes, Artificial