title: Osseous metaplasia in proliferative vitreoretinopathy.
abstract: OBJECTIVE
  To report the clinicopathologic features of intraocular osseous production in association with proliferative vitreoretinopathy.
  
  
  METHODS
  The clinical and histopathologic features of two patients with proliferative vitreoretinopathy and intraocular bone formation are reviewed.
  
  
  RESULTS
  Preretinal osseous tissue incorporated in the proliferative vitreoretinopathy was surgically removed in one patient, and osseous tissue was present in the proliferative vitreoretinopathy in the enucleated eye of the other patient.
  
  
  CONCLUSIONS
  Bone formation, presumably from metaplastic retinal pigment epithelium, may be present in proliferative vitreoretinopathy tissue. The intraocular bone is present internal rather than external to the neurosensory retina.
authors.affiliation: Department of Ophthalmology, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Y D
authors.initials: YD
authors.lastname: Yoon
authors.forename: T M
authors.initials: TM
authors.lastname: Aaberg
authors.forename: T H
authors.initials: TH
authors.lastname: Wojno
authors.forename: H E
authors.initials: HE
authors.lastname: Grossniklaus
mesh_terms: D000328:Adult; D015353:Eye Enucleation; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D008679:Metaplasia / Q000473:pathology; D009999:Ossification, Heterotopic / Q000150:complications* / Q000473:pathology / Q000601:surgery; D012160:Retina / Q000473:pathology*; D012163:Retinal Detachment / Q000150:complications / Q000601:surgery; D012164:Retinal Diseases / Q000150:complications* / Q000473:pathology / Q000601:surgery; D018630:Vitreoretinopathy, Proliferative / Q000150:complications* / Q000601:surgery