[Hepatolienal syndrome in patients with chronic lymphoid leukemia and liver cirrhosis: similarities and differences of macrophagal function].
Macrophagal function of the liver and spleen was studied using 99mTc dynamic scintigraphy in 31 patients with chronic lymphoid leukemia (CLL) and 11 patients with hepatic cirrhosis (HC). Total accumulation of the radionuclide in the above patients took place with more active participation of the spleen and less active--of the liver. Macrophagal function of the spleen and the liver was activated in CLL patients, whereas hepatic cirrhosis was accompanied by enhanced splenic function and diminished capacity of the liver for phagocytosis. Mechanisms of such phenomena are discussed.
Litvinov
A V
AV
Miliagin
V A
VA
D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D008099:Liver / Q000098:blood supply; D008103:Liver Cirrhosis / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D008264:Macrophages / Q000000981:diagnostic imaging / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D010587:Phagocytosis / Q000502:physiology; D011877:Radionuclide Imaging; D013154:Spleen / Q000098:blood supply; D013158:Splenic Diseases / Q000150:complications / Q000000981:diagnostic imaging* / Q000503:physiopathology; D013577:Syndrome