title: Familial hemiplegic migraine with irreversible brain damage.
abstract: Familial hemiplegic migraine (FHM) is an autosomal dominant syndrome characterized by recurrent episodes of varying degrees of hemiparesis associated with migraine. The aura including hemiparesis may be prolonged and in severe attacks may often be associated with confusion or coma. We describe a case of FHM whose aura was atypically prolonged and resulted in irreversible brain deficit which on magnetic resonance imaging (MRI) was suggestive of cortical hyperperfusion. A subsequent MRI showed left brain atrophy.
authors.affiliation: Department of Neurology, Yokohama City Hospital, Kanagawa.
authors.forename: R
authors.initials: R
authors.lastname: Hayashi
authors.forename: H
authors.initials: H
authors.lastname: Tachikawa
authors.forename: R
authors.initials: R
authors.lastname: Watanabe
authors.forename: M
authors.initials: M
authors.lastname: Honda
authors.forename: Y
authors.initials: Y
authors.lastname: Katsumata
mesh_terms: D000328:Adult; D001284:Atrophy; D001921:Brain / Q000473:pathology*; D003704:Dementia / Q000150:complications / Q000235:genetics; D005799:Genes, Dominant; D006429:Hemiplegia / Q000150:complications* / Q000235:genetics* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008881:Migraine Disorders / Q000150:complications* / Q000235:genetics* / Q000473:pathology; D013577:Syndrome