Comparison of the intraosseous biocompatibility of Dyract and Super EBA.
The purpose of this study was to compare the intraosseous biocompatibility of Dyract, a new hydrophilic glass-ionomer cement, to that of Super EBA. Twenty-four New Zealand rabbits were anesthetized, one leg was shaved, the femur exposed, and two holes were drilled through the cortical plate. The materials were loaded into silicone carriers and inserted into the femur. Half of the rabbits were killed 4 weeks after implantation and the other half at 12 weeks and the femurs were prepared using standard histological procedures. The tissue reactions were graded from none to severe. At 4 weeks both materials showed slight to moderate reactions, characterized by the presence of fibrous tissue interposition and inflammatory cells. At 12 weeks, bone healing had occurred, despite the persistence of some fibrous tissue interposition, and the reactions were classified as slight. At both observation periods, statistical analysis failed to show any difference between the two materials indicating that Dyract and Super EBA had similar intraosseous biocompatibility.
Pertot
W J
WJ
Unité Interface Matrice Extracellulaire Biomatériaux-EA 1787, Université de la Méditerranée, U.F.R. d'Odontologie, Marseille, France.
Stephan
G
G
Tardieu
C
C
Proust
J P
JP
D000818:Animals; D001672:Biocompatible Materials / Q000633:toxicity*; D001842:Bone and Bones / Q000187:drug effects; D020770:Compomers; D017220:Dentin-Bonding Agents / Q000633:toxicity*; D005269:Femur; D020007:Implants, Experimental; D008689:Methacrylates / Q000633:toxicity*; D011817:Rabbits; D012387:Root Canal Filling Materials / Q000633:toxicity*; D017640:Silicates / Q000633:toxicity*; D018709:Statistics, Nonparametric
D001672:Biocompatible Materials; D020770:Compomers; D017220:Dentin-Bonding Agents; C088486:Dyract; D008689:Methacrylates; D012387:Root Canal Filling Materials; D017640:Silicates; C084074:Super EBA