title: Duplication of the pituitary gland in a newborn with median cleft face syndrome and nasal teratoma.
abstract: A newborn suffered immediate neonatal respiratory distress because of an obstructive, soft-tissue nasal mass. Clinical examination revealed a cleft palate with a protruding polypoid mass. CT and MRI showed a heterogeneous nasopharyngeal mass and associated intracranial abnormalities - duplication of the hypophysis and hypoplasia of the corpus callosum. Duplication of the hypophysis is a very rare malformation, only 13 cases having been previously described. The suggested pathogenesis is duplication of the prechordal plate and anterior end of the notochord during early embryological development.
authors.affiliation: Service de Neuroradiologie, Hôpital Roger Salengro, CHRU Lille, France.
authors.forename: M
authors.initials: M
authors.lastname: Hamon-Kérautret
authors.forename: G S
authors.initials: GS
authors.lastname: Ares
authors.forename: X
authors.initials: X
authors.lastname: Demondion
authors.forename: V
authors.initials: V
authors.lastname: Rouland
authors.forename: J P
authors.initials: JP
authors.lastname: Francke
authors.forename: J P
authors.initials: JP
authors.lastname: Pruvo
mesh_terms: D002972:Cleft Palate / Q000150:complications*; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D009296:Nasal Cavity; D009669:Nose Neoplasms / Q000150:complications*; D010902:Pituitary Gland / Q000002:abnormalities*; D013577:Syndrome; D013724:Teratoma / Q000150:complications*; D014057:Tomography, X-Ray Computed