title: MRI-neuropathological correlations in type 1 lissencephaly.
abstract: Although imperfect, MRI is the best way of distinguishing type 1 lissencephaly from other, less classical lissencephalic malformations. We reported a case in which correlation of MRI and neuropathology was possible. Besides the classical radiological features of lissencephaly, i.e., agyria and excessive thickness of the cortex, an additional sign was observed: a thin cortical band, which gave high signal on T2-weighted images, represented a paucicellular and partially myelinated band, 1500 microns thick, lying under the true superficial cortex. This MRI feature could be characteristic of the particular cortical lamination observed in true type 1 lissencephaly.
authors.affiliation: Department of Paediatric Neurology, CHU Bicêtre, France.
authors.forename: P
authors.initials: P
authors.lastname: Landrieu
authors.forename: B
authors.initials: B
authors.lastname: Husson
authors.forename: D
authors.initials: D
authors.lastname: Pariente
authors.forename: C
authors.initials: C
authors.lastname: Lacroix
mesh_terms: D002540:Cerebral Cortex / Q000002:abnormalities*; D000013:Congenital Abnormalities / Q000175:diagnosis; D006801:Humans; D007223:Infant; D008279:Magnetic Resonance Imaging; D008297:Male