title: Effects of non-steroidal anti-inflammatory drugs and cyclooxygenase-2 specific inhibitors on mediator release from rat peritoneal mast cells.
authors.affiliation: Department of Pharmacology, Faculty of Medicine, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong. hyalau@cuhk.edu.hk
authors.forename: H Y
authors.initials: HY
authors.lastname: Lau
authors.forename: G R
authors.initials: GR
authors.lastname: Stenton
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D002118:Calcium / Q000378:metabolism; D051546:Cyclooxygenase 2; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors / Q000494:pharmacology*; D004789:Enzyme Activation / Q000187:drug effects; D005480:Flurbiprofen / Q000494:pharmacology; D006636:Histamine Release / Q000187:drug effects*; D007052:Ibuprofen / Q000494:pharmacology; D007073:Immunoglobulin E / Q000276:immunology; D007189:Indans / Q000494:pharmacology; D007213:Indomethacin / Q000494:pharmacology; D007527:Isoenzymes / Q000378:metabolism*; D008297:Male; D008407:Mast Cells / Q000187:drug effects* / Q000378:metabolism; D009280:Naphthaleneacetic Acids / Q000494:pharmacology; D009578:Nitrobenzenes / Q000494:pharmacology; D010529:Peritoneal Cavity / Q000166:cytology; D015230:Prostaglandin D2 / Q000096:biosynthesis; D011451:Prostaglandin-Endoperoxide Synthases / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013449:Sulfonamides / Q000494:pharmacology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D052246:Cyclooxygenase 2 Inhibitors; D016861:Cyclooxygenase Inhibitors; D007189:Indans; D007527:Isoenzymes; C093700:L 745337; D009280:Naphthaleneacetic Acids; D009578:Nitrobenzenes; D013449:Sulfonamides; C080955:N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide; D007073:Immunoglobulin E; D005480:Flurbiprofen; C044612:6-methoxy-2-naphthylacetic acid; D051546:Cyclooxygenase 2; D011451:Prostaglandin-Endoperoxide Synthases; D015230:Prostaglandin D2; D002118:Calcium; D007052:Ibuprofen; D007213:Indomethacin