title: Cloning and characterization of the genomic RNA sequence of the mumps virus strain associated with a high incidence of aseptic meningitis.
abstract: cDNA clones of the mumps virus wild-type strain, associated with a high incidence of aseptic meningitis (ODATE-1 strain), were isolated and analyzed from genomic nucleotide position 22 to 8520 containing the NP, P, M, F, SH and HN protein coding region. The ODATE-1 strain exhibited a RFLP profile identical to that of the Urabe vaccine strain in spite of the fact that the virus was isolated from non-vaccinated cases. However, a comparison of nucleotide and amino acid sequences among the ODATE-1 strain, Urabe strain and Miyahara strain revealed that the ODATE-1 strain was not related to the Urabe strain.
authors.affiliation: Department of Microbiology, Akita Prefectural Institute of Public Health, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Saito
authors.forename: Y
authors.initials: Y
authors.lastname: Takahashi
authors.forename: S
authors.initials: S
authors.lastname: Harata
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: H
authors.initials: H
authors.lastname: Sato
authors.forename: T
authors.initials: T
authors.lastname: Suto
authors.forename: A
authors.initials: A
authors.lastname: Yamada
authors.forename: S
authors.initials: S
authors.lastname: Yamazaki
authors.forename: M
authors.initials: M
authors.lastname: Morita
mesh_terms: D000818:Animals; D002522:Chlorocebus aethiops; D006801:Humans; D008582:Meningitis, Aseptic / Q000453:epidemiology / Q000821:virology*; D009109:Mumps virus / Q000235:genetics*; D012367:RNA, Viral / Q000737:chemistry*; D017423:Sequence Analysis, RNA; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity; D014709:Vero Cells
chemical_list: D012367:RNA, Viral