Peroxisome biogenesis: back to the endoplasmic reticulum?
Proteins are targeted to the membrane and matrix of peroxisomes by distinct pathways. Recent observations suggest a further route: a subset of peroxisomal membrane proteins might be targeted first to the endoplasmic reticulum, and from there to peroxisomes by vesicle-mediated transport.
Kunau
W H
WH
Institut für Physiologische Chemie, Ruhr-Universität Bochum, 44780 Bochum, Germany. Wolf-H.Kunau@ruhr-uni-bochum.de
Erdmann
R
R
D000818:Animals; D001693:Biological Transport, Active; D020756:Coatomer Protein; D004721:Endoplasmic Reticulum / Q000378:metabolism*; D006031:Glycosylation; D006801:Humans; D008099:Liver / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D008830:Microbodies / Q000378:metabolism*; D008954:Models, Biological; D010750:Phosphoproteins / Q000378:metabolism; D011485:Protein Binding; D029701:Saccharomyces cerevisiae Proteins
D020756:Coatomer Protein; D008565:Membrane Proteins; C110177:PEX15 protein, S cerevisiae; D010750:Phosphoproteins; D029701:Saccharomyces cerevisiae Proteins