title: Urinary excretion of orally ingested gastrografin on CT.
abstract: Renal excretion of orally ingested gastrografin has rarely been reported on computed tomography (CT). We studied the unenhanced scans of 82 patients with bowel disorders or perforation to assess the prevalence of urinary contrast material (CM) in various bowel diseases. We also assessed the clinical significance of this sign. In addition, we reviewed the unenhanced CT scans of 100 randomly selected patients without bowel diseases as a control group. Twenty-nine of the 58 patients with bowel diseases, six of nine with free perforation, and one of 15 with covered perforation had CM in the urinary tract. None of the 100 without bowel disease showed urinary CM. Statistical analysis was done by using the Fisher's exact test. The prevalence of urinary CM was highest in inflammatory bowel disease, radiation enteritis, and free perforation (p < 0. 0001). This study shows that the CT finding of orally ingested gastrografin in the urinary tract differentiates patients with bowel disease from those without.
authors.affiliation: Department of Imaging, Chaim Sheba Medical Center, Tel Hashomer, Israel
authors.forename: S
authors.initials: S
authors.lastname: Apter
authors.forename: G
authors.initials: G
authors.lastname: Gayer
authors.forename: M
authors.initials: M
authors.lastname: Amitai
authors.forename: M
authors.initials: M
authors.lastname: Hertz
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003287:Contrast Media / Q000008:administration & dosage / Q000493:pharmacokinetics*; D003974:Diatrizoate Meglumine / Q000008:administration & dosage / Q000493:pharmacokinetics* / Q000652:urine; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000000981:diagnostic imaging / Q000652:urine*; D007414:Intestinal Neoplasms / Q000000981:diagnostic imaging / Q000652:urine; D008297:Male; D008875:Middle Aged; D012422:Rupture, Spontaneous; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D003974:Diatrizoate Meglumine