Cytogenetics of an atypical Spitz nevus metastatic to a single lymph node.
Clinicopathologic details of an atypical Spitz nevus are reported. A metastasis to a single ipsilateral lymph node is documented. Cytogenetic analysis of the metastatic lesion revealed a clonal chromosomal abnormality, add(6)(q12-13), previously noted in cases of malignant melanoma.
Smith
N M
NM
Department of Paediatric Pathology, Royal Hospital for Sick Children, Edinburgh, United Kingdom.
Evans
M J
MJ
Pearce
A
A
Wallace
W H
WH
D002869:Chromosome Aberrations; D002896:Chromosomes, Human, Pair 6; D005260:Female; D006801:Humans; D007223:Infant; D008207:Lymphatic Metastasis; D008545:Melanoma / Q000235:genetics; D018332:Nevus, Epithelioid and Spindle Cell / Q000235:genetics / Q000473:pathology*; D012878:Skin Neoplasms / Q000235:genetics / Q000473:pathology*