Cutaneous epithelioid angioleiomyoma.
We describe an unusual dermal neoplasm with epithelioid morphology. A 44-year-old man presented with a solitary, tender, 4-mm nodule on the leg. Excisional biopsy showed several well-circumscribed dermal epithelioid tumor nodules, prominent vascularity, and smooth muscle differentiation. We suggest the term cutaneous epithelioid angioleiomyoma for this neoplasm. In a review of the literature, we found reports of two similar cases and a recent report describing five cutaneous epithelioid leiomyosarcomas. Cutaneous epithelioid angioleiomyoma represents a rare variant of dermal smooth muscle tumor and could represent the benign counterpart to the recently described epithelioid leiomyosarcoma of the skin.
Heffernan
M P
MP
Department of Dermatology, Stanford University School of Medicine, California, USA.
Smoller
B R
BR
Kohler
S
S
D000199:Actins / Q000032:analysis; D000328:Adult; D018229:Angiomyoma / Q000737:chemistry / Q000473:pathology*; D018952:Antigens, CD34 / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D018230:Leiomyoma, Epithelioid / Q000737:chemistry / Q000473:pathology*; D008297:Male; D012878:Skin Neoplasms / Q000737:chemistry / Q000473:pathology*
D000199:Actins; D018952:Antigens, CD34; D014408:Biomarkers, Tumor