title: Meningitis due to a combined infection with Cryptococcus neoformans and Streptococcus pneumoniae in an AIDS patient.
abstract: We report on a case of dual infection with Cryptococcus neoformans and Streptococcus pneumoniae in the cerebrospinal fluid of a patient with AIDS. To our knowledge this represents the first case to be reported in the English literature. In immunocompromised patients the importance of performing both the Gram- and India-ink stain and cryptococcal antigen test on CSF specimens with completely normal biochemical and cellular parameters is emphasized.
authors.affiliation: Department of Medical Microbiology, University of Natal Medical School, Durban, South Africa.
authors.forename: M A
authors.initials: MA
authors.lastname: John
authors.forename: Y
authors.initials: Y
authors.lastname: Coovadia
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis*; D000328:Adult; D000946:Antigens, Fungal / Q000032:analysis; D002244:Carbon; D002555:Cerebrospinal Fluid / Q000382:microbiology; D004396:Coloring Agents; D003455:Cryptococcus neoformans / Q000302:isolation & purification; D005260:Female; D005840:Gentian Violet; D006801:Humans; D016919:Meningitis, Cryptococcal / Q000175:diagnosis*; D008586:Meningitis, Pneumococcal / Q000175:diagnosis*; D010619:Phenazines; D013194:Staining and Labeling; D013296:Streptococcus pneumoniae / Q000302:isolation & purification
chemical_list: D000946:Antigens, Fungal; D004396:Coloring Agents; C035863:Gram's stain; D010619:Phenazines; C028433:chinese ink; D002244:Carbon; D005840:Gentian Violet