title: Protein engineering aspartic proteinases. Site-directed mutagenesis, biochemical characterisation, and X-ray analysis of chymosins with substituted single amino acid substitutions and loop replacements.
authors.affiliation: Department of Crystallography, Birkbeck College, University of London, United Kingdom.
authors.forename: A
authors.initials: A
authors.lastname: Albert
authors.forename: T L
authors.initials: TL
authors.lastname: Blundell
authors.forename: V
authors.initials: V
authors.lastname: Dhanaraj
authors.forename: L E
authors.initials: LE
authors.lastname: Donate
authors.forename: M
authors.initials: M
authors.lastname: Groves
authors.forename: K
authors.initials: K
authors.lastname: Guruprasad
authors.forename: P G
authors.initials: PG
authors.lastname: Nugent
authors.forename: P
authors.initials: P
authors.lastname: Orprayoon
authors.forename: J E
authors.initials: JE
authors.lastname: Pitts
authors.forename: S
authors.initials: S
authors.lastname: Rufino
authors.forename: N
authors.initials: N
authors.lastname: Srinivasan
authors.forename: M
authors.initials: M
authors.lastname: Williams
authors.forename: J
authors.initials: J
authors.lastname: Wilsher
mesh_terms: D000596:Amino Acids; D000818:Animals; D012085:Chymosin / Q000737:chemistry* / Q000235:genetics*; D018360:Crystallography, X-Ray; D015870:Gene Expression; D016297:Mutagenesis, Site-Directed; D015202:Protein Engineering / Q000379:methods*; D017433:Protein Structure, Secondary; D011993:Recombinant Fusion Proteins / Q000737:chemistry / Q000235:genetics
chemical_list: D000596:Amino Acids; D011993:Recombinant Fusion Proteins; D012085:Chymosin