title: Comparison of simultaneous patch testing with parthenolide and sesquiterpene lactone mix.
abstract: Several studies have pointed out that the sesquiterpene lactone (SL) mix is a safe, though inadequate, screen for Compositae allergy. To test the usefulness of the sesquiterpene lactone parthenolide as a supplementary Compositae screening test to the mix, both were included in the standard series in 2 Danish dermatology departments. Among 2244 patients tested, 46 (2%) were positive to SL mix and 73-75% of these were positive to parthenolide. The results demonstrate that parthenolide is not suitable as a supplementary screening agent to SL mix, but may be a fairly good screen on its own if the mix is not available.
authors.affiliation: Department of Dermatology, Tel-Aviv Medical Center, Israel.
authors.forename: E
authors.initials: E
authors.lastname: Orion
authors.forename: E
authors.initials: E
authors.lastname: Paulsen
authors.forename: K E
authors.initials: KE
authors.lastname: Andersen
authors.forename: T
authors.initials: T
authors.lastname: Menné
mesh_terms: D019659:Asteraceae / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D006801:Humans; D010328:Patch Tests / Q000379:methods*; D010946:Plants, Medicinal / Q000009:adverse effects*; D012717:Sesquiterpenes / Q000009:adverse effects*
chemical_list: D012717:Sesquiterpenes; C002669:parthenolide