title: Granulomatous hepatitis in pasteurella multocida infection.
abstract: Numerous diseases can lead to multilocular lesions of the liver. The authors report a rare pediatric case of hepatic granulomas due to Pasteurella multocida: a 7-year-old girl with chronic fever was investigated by sonography and CT scan, demonstrating mesenteric lymph node enlargement and numerous small hepatic lesions. After surgical biopsy, histopathology of the liver specimens showed pyogenic granuloma, with serologic testing positive for Pasteurella multocida. Treatment with a tetracycline and corticosteroids was successful. Pasteurella multocida infection, despite its habitual benign course, should be suspected among differential diagnoses of lymphogranulomatous affections with hepatic involvement. No case of liver and lymph node foci in a child has been previously described.
authors.affiliation: Service de Radiologie A, Hôpital Pellegrin, Place A Raba Léon, F-33076, Bordeaux Cedex, France.
authors.forename: J F
authors.initials: JF
authors.lastname: Chateil
authors.forename: M
authors.initials: M
authors.lastname: Brun
authors.forename: Y
authors.initials: Y
authors.lastname: Perel
authors.forename: J C
authors.initials: JC
authors.lastname: Sananes
authors.forename: J F
authors.initials: JF
authors.lastname: Castell
authors.forename: F
authors.initials: F
authors.lastname: Diard
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000907:Antibodies, Bacterial / Q000032:analysis; D002648:Child; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006099:Granuloma / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D006505:Hepatitis / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D006801:Humans; D008206:Lymphatic Diseases / Q000175:diagnosis / Q000382:microbiology / Q000628:therapy; D010326:Pasteurella Infections / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D016979:Pasteurella multocida / Q000276:immunology; D013752:Tetracycline / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D000900:Anti-Bacterial Agents; D000907:Antibodies, Bacterial; D005938:Glucocorticoids; D013752:Tetracycline