Synthesis of some new aroyl/aryloxy-2-amino-1,3-thiazole derivatives with anti-inflammatory activity.
The synthesis of some novel aroyl/aryloxy aminothiazoles from the appropriate gamma-chloro-butyrophenones, gamma-chloro-butyrothienones, gamma-chloro-aryloxypropanes with the corresponding substituted 2-amino-1,3-thiazoles is described. The spectroscopical data (UV, IR, 1H-NMR and MS) of the derivatives are presented.
Geronikaki
A A
AA
Department of Pharmaceutical Chemistry, School of Pharmacy, Aristotelian University of Thessaloniki, Greece.
Hadjipavlou-Litina
D J
DJ
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D000894:Anti-Inflammatory Agents, Non-Steroidal; D013844:Thiazoles