title: Stereotactic core needle biopsy of nonpalpable breast lesions: initial experience with a promising technique.
abstract: OBJECTIVE
  To evaluate the correlation between the pathological findings of stereotactic core needle biopsy (SCNB) and the prebiopsy mammographic findings, as well as the pathological findings of lesions that were subsequently removed by surgical excision.
  
  
  METHODS
  A retrospective review of 97 consecutive patients who underwent 100 SCNBs of suspicious nonpalpable mammographic lesions. The criterion standard is surgical excisional biopsy with needle localization. Mammographic findings were graded according to the American College of Radiology Breast Imaging Reporting and Data System. The pathological findings of SCNB were categorized into 4 groups: benign and specific, benign and nonspecific, premalignant, and malignant. Surgical excision of the lesion was performed if the pathological finding on SCNB was nonconcordant with the prebiopsy mammogram and when premalignant or malignant lesions were found. The pathological findings of lesions that were subsequently removed by surgical excision were compared with those of SCNB.
  
  
  METHODS
  Community-based private multispecialty ambulatory practice.
  
  
  METHODS
  A population-based sample composed of 97 patients who had grade III, IV, or V lesions on routine screening mammograms.
  
  
  METHODS
  Stereotactic core needle biopsy of nonpalpable mammographic lesions.
  
  
  METHODS
  Percentage of patients whose SCNB results were concordant with the mammographic findings and the pathological findings on subsequent surgical excision.
  
  
  RESULTS
  Concordance between SCNB and mammography occurred in 97% of biopsy specimens. Concordance between the pathological findings of SCNB and those of surgically excised lesions occurred in 92.5% of biopsy specimens. We had 1 false-negative result. We had no false-positive diagnosis of cancer with SCNB.
  
  
  CONCLUSIONS
  On the basis of accumulating literature and our own initial experience, SCNB is a promising, safe, and cost-effective procedure.
authors.affiliation: Department of Surgery, University of Massachusetts Medical School, Berkshire Medical Center, Pittsfield 01201, USA.
authors.forename: H
authors.initials: H
authors.lastname: Seoudi
authors.forename: J
authors.initials: J
authors.lastname: Mortier
authors.forename: R
authors.initials: R
authors.lastname: Basile
authors.forename: E
authors.initials: E
authors.lastname: Curletti
mesh_terms: D001707:Biopsy, Needle / Q000379:methods*; D001940:Breast / Q000473:pathology*; D001941:Breast Diseases / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000473:pathology; D001943:Breast Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000473:pathology*; D016022:Case-Control Studies; D005188:False Negative Reactions; D005260:Female; D006801:Humans; D008327:Mammography; D008875:Middle Aged; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D013238:Stereotaxic Techniques