title: Dynamic and randomized perturbed posturography in the follow-up of patients with polyneuropathy.
abstract: BACKGROUND
  The purpose of the study was to investigate and follow the equilibrium performance of patients with chronic polyneuropathy using Dynamic Posturography (DP) and Randomized Perturbed Posturography (RPP).
  
  
  METHODS
  Fourteen patients with chronic polyneuropathy, aged 53-83 years, were evaluated by clinical investigation, vibrametry, DP and RPP in a six-year follow-up. The patient group was compared to 14 healthy volunteers, aged 63-80 years. The DP comprises a sensory organization (SO) part in which the platform and visual surround are stable or referenced to the patient sway, with eyes open or closed. In a movement coordination (MC) part, the platform makes active movements. In RPP, the platform moves randomly in the anteroposterior direction.
  
  
  RESULTS
  Comparison between the first and second study of the patient group showed decreased equilibrium scores under stable conditions and when vision was excluded. Compared with controls, the patients showed significantly lower scores in most of the SO test conditions except when the platform was sway referenced with stable surround; in the MC part, the patients showed prolonged muscular response latencies, and in the RPP, the patients showed increased sway areas.
  
  
  CONCLUSIONS
  The results are further evidence that proprioception is probably the single most important sensory input for postural control in humans. Posturography proved to be an objective method to study and follow the equilibrium performance in patients with PN.
authors.affiliation: Audiology and Neuro-otology Department, Hospital General Centro Médico La Raza, Instituto Mexicano del Seguro Social, México, D.F., México. kjauren@data.net.mx
authors.forename: K
authors.initials: K
authors.lastname: Jáuregui-Renaud
authors.forename: B
authors.initials: B
authors.lastname: Kovacsovics
authors.forename: M
authors.initials: M
authors.lastname: Vrethem
authors.forename: L M
authors.initials: LM
authors.lastname: Odjvist
authors.forename: T
authors.initials: T
authors.lastname: Ledin
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D004856:Postural Balance / Q000502:physiology*; D011187:Posture / Q000502:physiology*; D014724:Vestibular Function Tests