Parathyroid hormone induction of cyclooxygenase-2 expression in human osteoblasts depends on both cyclic AMP and calcium-dependent pathways.
Fernandes
A J
AJ
Rheumatic Diseases Unit, Faculty of Medicine, University of Sherbrooke, Québec, Canada.
Lora
M
M
Patry
C
C
Morisset
S
S
Sarrazin
P
P
Maciel
F
F
D003994:Bucladesine / Q000494:pharmacology; D002118:Calcium / Q000378:metabolism*; D002121:Calcium Channel Blockers / Q000494:pharmacology; D002478:Cells, Cultured; D005576:Colforsin / Q000494:pharmacology; D000242:Cyclic AMP / Q000378:metabolism*; D051546:Cyclooxygenase 2; D003907:Dexamethasone / Q000494:pharmacology; D004790:Enzyme Induction; D006801:Humans; D007527:Isoenzymes / Q000096:biosynthesis*; D008565:Membrane Proteins; D009543:Nifedipine / Q000494:pharmacology; D010006:Osteoblasts / Q000187:drug effects / Q000201:enzymology / Q000502:physiology*; D010281:Parathyroid Hormone / Q000494:pharmacology*; D011451:Prostaglandin-Endoperoxide Synthases / Q000096:biosynthesis*; D012333:RNA, Messenger / Q000096:biosynthesis; D015398:Signal Transduction / Q000187:drug effects; D014158:Transcription, Genetic / Q000187:drug effects; D014700:Verapamil / Q000494:pharmacology
D002121:Calcium Channel Blockers; D007527:Isoenzymes; D008565:Membrane Proteins; D010281:Parathyroid Hormone; D012333:RNA, Messenger; D005576:Colforsin; D003994:Bucladesine; D003907:Dexamethasone; D014700:Verapamil; D000242:Cyclic AMP; D051546:Cyclooxygenase 2; C496540:PTGS2 protein, human; D011451:Prostaglandin-Endoperoxide Synthases; D009543:Nifedipine; D002118:Calcium