title: Langerhans cell histiocytosis in adults.
abstract: Langerhans cell histiocytosis in the adult is rare, but it is important to recognize its occurrence, as it must be differentiated from lymphoma, myeloma, and a variety of skin conditions and endocrinopathies. It has been reported in patients up to the ninth decade of life, and occurs equally in men and women. Local disease has a good prognosis, but associated diseases--particularly malignancy--may be the cause of death in some adults. The optimal treatment is not known. Coordinated investigation of the epidemiology and therapy of this disease is needed.
authors.affiliation: Imperial Cancer Research Fund, Department of Medical Oncology, St. Bartholomew's Hospital, London, United Kingdom.
authors.forename: J S
authors.initials: JS
authors.lastname: Malpas
mesh_terms: D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000473:pathology* / Q000503:physiopathology*; D006801:Humans; D008297:Male