title: An unusual dienone-phenol rearrangement product formed during the synthesis of mometasone furoate (Sch 32088).
abstract: The structure of an unusual dienone-phenol rearrangement product 4 obtained during the synthesis of mometasone furoate (Sch 32088) was assigned on the basis of NMR and x-ray crystallographic data. The mechanism of formation is discussed.
authors.affiliation: Chemical Process Development Department, Schering-Plough Research Institute, Kenilworth, New Jersey 07033-0539, USA.
authors.forename: R W
authors.initials: RW
authors.lastname: Draper
authors.forename: M S
authors.initials: MS
authors.lastname: Puar
authors.forename: E J
authors.initials: EJ
authors.lastname: Vater
authors.forename: A T
authors.initials: AT
authors.lastname: McPhail
mesh_terms: D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis* / Q000737:chemistry; D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D000068656:Mometasone Furoate; D010636:Phenols / Q000737:chemistry*; D011244:Pregnadienediols / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D000893:Anti-Inflammatory Agents; D010636:Phenols; D011244:Pregnadienediols; D000068656:Mometasone Furoate