Birth weight, gestational age and medications during pregnancy.
OBJECTIVE
To determine the effect of medication on birth weight and gestational age in 29,004 healthy newborn infants born to mothers with or without treatment of drugs.


METHODS
Birth weight and gestational age were evaluated in healthy control newborn infants in the population-based dataset of the Hungarian Case-Control Surveillance of Congenital Abnormalities (1980-1991) using multiple regression analysis.


RESULTS
Of 114 drugs used in more than 100 pregnant women, 19 had a positive or negative impact.


CONCLUSIONS
Further studies should be carried out to identify the possible mechanisms of medication and/or the maternal disorder for which this medication was given.
Czeizel
A E
AE
Department of Human Genetics and Teratology, National Institute of Hygiene-WHO Collaborating Centre for the Community Control of Hereditary Diseases, Budapest, Hungary.
Tóth
M
M
D001724:Birth Weight / Q000187:drug effects*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy / Q000187:drug effects*; D011248:Pregnancy Complications / Q000188:drug therapy*; D011256:Pregnancy Outcome