Composite biomaterials with chemical bonding between hydroxyapatite filler particles and PEG/PBT copolymer matrix.
In an effort to make composites from hydroxyapatite and a PEG/PBT copolymer (Polyactive 70/30), chemical linkages were introduced between the filler particles and polymer matrix using hexamethylene diisocyanate as a coupling agent. Infrared spectra (IR) and thermal gravimetric analysis (TGA) confirmed the presence of Polyactive 70/30 on the surface of HA filler particles. The amount of chemically bound polymer was 4.7 wt.%, as determined by TGA. The mechanical properties of the composites, that is, tensile strength and Young's modulus, were improved significantly by the introduction of a chemical linkage between the filler particles and polymer matrix compared to control composites. This method provides an effective way to introduce chemical linkage between HA filler particles and a polymer matrix. By optimizing the grafting process, a further improvement of the mechanical properties in the composites can be expected.
Liu
Q
Q
Biomaterials Research Group, Leiden University, Bilthoven, The Netherlands. Qing@Ruf.Rice.Edu
de Wijn
J R
JR
van Blitterswijk
C A
CA
D003188:Composite Resins; D017886:Durapatite; D004548:Elasticity; D008422:Materials Testing; D019563:Mechanics; D011091:Polyesters / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry*; D011208:Powders; D013055:Spectrophotometry, Infrared; D013499:Surface Properties; D013718:Tensile Strength
D003188:Composite Resins; D011091:Polyesters; D011208:Powders; C041733:poly(1,4-butylene terephthalate); D011092:Polyethylene Glycols; D017886:Durapatite