title: Conservative management of superior mesenteric and portal vein thrombosis associated with protein C and S deficiency. Case report.
abstract: Protein C and S, vitamin K-dependent proteins, are blood coagulation inhibitors. Their deficiency causes systemic thrombosis. A 35-year-old man who developed superior mesenteric venous thrombosis and portal vein thrombosis showed markedly decreased protein C and S levels. The therapeutic modality of this thrombosis associated with protein C and S deficiency is still debated. We treated this patient with systemic anticoagulation and long term total parenteral nutrition without surgical intervention.
authors.affiliation: Department of General Surgery, Samsung Medical Center, Seoul, Korea.
authors.forename: D I
authors.initials: DI
authors.lastname: Kim
authors.forename: B B
authors.initials: BB
authors.lastname: Lee
authors.forename: S I
authors.initials: SI
authors.lastname: Noh
authors.forename: Y H
authors.initials: YH
authors.lastname: Baek
authors.forename: J W
authors.initials: JW
authors.lastname: Joh
authors.forename: S K
authors.initials: SK
authors.lastname: Lee
authors.forename: Y I
authors.initials: YI
authors.lastname: Kim
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008642:Mesenteric Veins; D010288:Parenteral Nutrition; D011169:Portal Vein; D011172:Portography; D020151:Protein C Deficiency; D018455:Protein S Deficiency / Q000097:blood / Q000150:complications* / Q000628:therapy; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D014057:Tomography, X-Ray Computed
chemical_list: D000925:Anticoagulants