title: Insulin resistance, dehydroepiandrosterone sulfate and sex hormone-binding globulin in essential hypertension.
abstract: OBJECTIVE
  To evaluate insulin sensitivity, and serum levels of sex hormone-binding globulin (SHBG) and dehydroepiandrosterone sulfate (DHEA-sulfate), in patients with essential hypertension.
  
  
  METHODS
  In 15 non-treated hypertensive patients, insulin resistance was measured by an insulin suppression test (IST). Serum levels of DHEA-sulfate and SHBG were measured at the beginning and at the end of the IST. The results were compared to those of a control group of 10 healthy normotensive subjects matched for age, sex and body mass index (BMI).
authors.affiliation: Department of Endocrinology, Hospital General Universitario de Alicante, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Serrano-Gotarredona
authors.forename: H F
authors.initials: HF
authors.lastname: Escobar-Morreale
authors.forename: J M
authors.initials: JM
authors.lastname: Sancho
authors.forename: R
authors.initials: R
authors.lastname: García-Robles
mesh_terms: D000368:Aged; D001786:Blood Glucose / Q000378:metabolism; D015992:Body Mass Index; D019314:Dehydroepiandrosterone Sulfate / Q000097:blood*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood*; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D008297:Male; D008875:Middle Aged; D012738:Sex Hormone-Binding Globulin / Q000378:metabolism*; D013004:Somatostatin
chemical_list: D001786:Blood Glucose; D007328:Insulin; D012738:Sex Hormone-Binding Globulin; D013004:Somatostatin; D019314:Dehydroepiandrosterone Sulfate