title: Population genetics: surviving under mutation pressure.
abstract: Concern has been voiced about the survival of endangered species, and even the long-term prospects for humans, in the face of accumulating deleterious mutations. Two experiments have investigated the mutation accumulation process in laboratory Drosophila populations, with apparently conflicting results.
authors.affiliation: Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT, Scotland.
authors.forename: P D
authors.initials: PD
authors.lastname: Keightley
authors.forename: A
authors.initials: A
authors.lastname: Caballero
authors.forename: A
authors.initials: A
authors.lastname: García-Dorado
mesh_terms: D000818:Animals; D004330:Drosophila / Q000235:genetics; D005260:Female; D005828:Genetics, Population; D006801:Humans; D008297:Male; D008957:Models, Genetic; D009154:Mutation; D012641:Selection, Genetic