title: [Osteo-conductive materials: animal experiments and instrumental analysis II].
abstract: BACKGROUND
  In daily dental surgery practice, when it is not possible to obtain-enough autogenous bone graft to fill bone defects, bone substitutes can be useful for bone regeneration.
  
  
  METHODS
  After a preliminary microscopic examination of histologic samples obtained from semithin sections of the tibias of rats showing no major differences in the results both for the single material and implant time, further studies on five different osteoconductive materials used in oral clinical practice were carried out with microradiography, SEM and X-ray microanalysis. In experimental animals (rats) bone defects 3 mm large were surgically induced in both tibias: one of the defects was filled by bone substitutes and on the other side the bone defect healed naturally.
  
  
  CONCLUSIONS
  The findings obtained were studied in depth, and allowed to conclude that the materials tested are suitable for the purpose for which they are marketed. Non-demineralized bovine bone showed the best results with a high degree of osteointegration. However, the results also show that not all the materials tested offer healing advantages over controls.
authors.affiliation: Istituto di Discipline Odontostomatologiche, Università degli Studi, Pavia.
authors.forename: R
authors.initials: R
authors.lastname: Rodriguez y Baena
authors.forename: D
authors.initials: D
authors.lastname: Zaffe
authors.forename: C
authors.initials: C
authors.lastname: Brusotti
authors.forename: C
authors.initials: C
authors.lastname: Marchetti
authors.forename: A
authors.initials: A
authors.lastname: Botticelli
authors.forename: S
authors.initials: S
authors.lastname: Rizzo
mesh_terms: D000818:Animals; D001844:Bone Conduction; D001861:Bone Regeneration; D016025:Bone Transplantation; D001842:Bone and Bones / Q000648:ultrastructure; D002417:Cattle; D003764:Dental Materials; D006801:Humans; D008854:Microscopy, Electron; D051381:Rats; D013515:Surgery, Oral; D014183:Transplantation, Heterologous
chemical_list: D003764:Dental Materials