Antibacterial activity of rhodium, iridium, and ruthenium tripodal phosphine complexes.
Twenty-eight rhodium, iridium, or ruthenium complexes were evaluated for their in vitro antibacterial activity against Enterococcus faecalis ATCC 29212, Staphylococcus aureus ATCC 29213, Escherichia coli ATCC 25922 and Pseudomonaa aeruginosa ATCC 27853. Ten compounds showed an antibacterial activity against Enterococcus faecalis ATCC 29212 and Staphylococcus aureus ATCC 29213 with a range of the minimum inhibitory concentrations (MICs) between 16 and 125 micrograms/ml. None of the compounds exhibited antimicrobial activity against the gram-negative strains E. coli ATCC 25922 or Pseudomonas aeruginosa ATCC 29213 with a concentration range between 4 and 500 micrograms/ml.
Sülü
M
M
Department of Chemistry, Faculty of Arts and Sciences, Inönü University, Malatya, Turkey.
Küçükbay
H
H
Durmaz
R
R
Günal
S
S
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D007495:Iridium / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000494:pharmacology; D012238:Rhodium / Q000494:pharmacology; D012428:Ruthenium / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D009942:Organometallic Compounds; D007495:Iridium; D012428:Ruthenium; D012238:Rhodium