title: Fourier transform infrared and Raman microspectroscopy of materials in tissue.
abstract: Fourier transform infrared and Raman (FT-IR and FT-Raman) microspectroscopy were used to study materials found in human tissue. Individual cases involving cholesterol, calcium stearate, and a polystyrenesulfonate ion exchange resin demonstrate the utility of the spectroscopic data. Characteristic spectral bands for these materials were compared with those of authentic chemical species to confirm their identities. The role of vibrational spectroscopy in pathologic diagnoses is discussed.
authors.affiliation: Department of Environmental and Toxicologic Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000, USA.
authors.forename: V F
authors.initials: VF
authors.lastname: Kalasinsky
authors.forename: F B
authors.initials: FB
authors.lastname: Johnson
authors.forename: R
authors.initials: R
authors.lastname: Ferwerda
mesh_terms: D002784:Cholesterol / Q000032:analysis; D019963:Clinical Chemistry Tests / Q000379:methods*; D005227:Fatty Acids / Q000032:analysis; D006801:Humans; D011137:Polystyrenes / Q000032:analysis; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods*; D013059:Spectrum Analysis, Raman / Q000379:methods*
chemical_list: D005227:Fatty Acids; D011137:Polystyrenes; C003321:polystyrene sulfonic acid; D002784:Cholesterol