Trans-acting factor(s) confer glucose-responsive transcriptional regulation in the insulin gene.
Goodison
S
S
University of Oxford, Nuffield Dept. of Clinical Biochemistry, John Radcliffe Hospital, Headington, United Kingdom.
Ashcroft
S J
SJ
D000818:Animals; D002460:Cell Line; D002467:Cell Nucleus / Q000378:metabolism; D005786:Gene Expression Regulation / Q000187:drug effects*; D017930:Genes, Reporter; D005947:Glucose / Q000494:pharmacology*; D007328:Insulin / Q000096:biosynthesis* / Q000235:genetics; D007515:Islets of Langerhans / Q000378:metabolism*; D011401:Promoter Regions, Genetic; D011993:Recombinant Fusion Proteins / Q000096:biosynthesis; D015534:Trans-Activators / Q000378:metabolism*; D014158:Transcription, Genetic / Q000187:drug effects*; D014162:Transfection
D007328:Insulin; D011993:Recombinant Fusion Proteins; D015534:Trans-Activators; D005947:Glucose