title: Uterine and ovarian conservation in advanced small cell carcinoma of the ovary.
abstract: BACKGROUND
  The decision to recommend removal or conservation of a normal ovary and uterus in a young woman with advanced ovarian cancer is difficult and controversial.
  
  
  METHODS
  A 21-year-old patient with a large-cell variant of small-cell carcinoma of the ovary stage IIIc underwent optimal debulking surgery with preservation of the normal appearing uterus and opposite adnexa followed by aggressive multi-agent chemotherapy. She is menstruating normally and is free of disease, more than 2 years since completion of chemotherapy.
  
  
  CONCLUSIONS
  In selected cases, conservation of the uninvolved ovary and uterus in patients with advanced-stage, small-cell carcinoma of the ovary may not compromise survival.
authors.affiliation: Department of Obstetrics and Gynecology, Coastal Area Health Education Center, New Hanover Regional Medical Center, Wilmington, North Carolina 28402-9025, USA.
authors.forename: J L
authors.initials: JL
authors.lastname: Powell
authors.forename: R D
authors.initials: RD
authors.lastname: McAfee
authors.forename: R C
authors.initials: RC
authors.lastname: McCoy
authors.forename: B S
authors.initials: BS
authors.lastname: Shiro
mesh_terms: D000328:Adult; D018288:Carcinoma, Small Cell / Q000473:pathology / Q000556:secondary / Q000601:surgery*; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery*