Update of the gene discovery program in Schistosoma mansoni with the expressed sequence tag approach.
Continuing the Schistosoma mansoni Genome Project 363 new templates were sequenced generating 205 more ESTs corresponding to 91 genes. Seventy four of these genes (81%) had not previously been described in S. mansoni. Among the newly discovered genes there are several of significant biological interest such as synaptophysin, NIFs-like and rho-GDP dissociation inhibitor.
Rabelo
E M
EM
Departamento de Parasitologia, Universidade Federal de Minas Gerais, Belo Horizonte, Brasil.
Franco
G R
GR
Azevedo
V A
VA
Pena
H B
HB
Santos
T M
TM
Meira
W S
WS
Rodrigues
N A
NA
Ortega
J M
JM
Pena
S D
SD
D000818:Animals; D002874:Chromosome Mapping; D018509:DNA, Helminth; D016678:Genome; D012550:Schistosoma mansoni / Q000235:genetics*; D012689:Sequence Homology, Nucleic Acid; D016324:Sequence Tagged Sites
D018509:DNA, Helminth