title: Clinical outcome and bowel function following total abdominal colectomy and ileorectal anastomosis in the Oriental population.
abstract: Total abdominal colectomy with ileorectal anastomosis is a commonly performed surgical procedure. The postoperative outcome of these patients, however, has not been studied in detail in the Asian population.
  
  
  OBJECTIVE
  The purpose of this study was to analyze the functional outcome of patients following total abdominal colectomy and ileorectal anastomosis.
  
  
  METHODS
  All patients subjected to a total abdominal colectomy with ileorectal anastomosis during a six-year period from February 1989 to October 1995 were reviewed.
  
  
  RESULTS
  Sixty-six patients (male:female, 40:26) with a mean age of 55.2 (range, 20-88) years underwent total abdominal colectomy with ileorectal anastomosis. Median follow-up after surgery was 26 (range, 4-78) months. Indications for surgery were synchronous or metachronous tumors (18), complicated pancolonic diverticular disease (15), obstructed tumors with impending perforation (13), familial adenomatous polyposis (7), slow-transit constipation (6), and others (7). Mean operative time was 137 +/- 48 minutes. Mean postoperative hospitalization was 13.3 +/- 11.9 days. Time to first bowel movement and commencement of solid diet were 4.7 +/- 1.8 and 7.2 +/- 2.4 days, respectively. Four patients had prolonged postoperative ileus. Average stool frequencies per day were 5.5 at one week, 4.3 at one month, 3.9 at six months, 3.2 at one year, and 2.9 at two years postoperatively. Thirty-three patients (50 percent) required antidiarrheal treatment for a transient period, but none required long-term therapy. Ninety-seven percent of all patients rated the functional outcome as good to excellent, and 3 percent said it was fair. There was two perioperative mortalities. Five cases required re-laparotomy, three for anastomotic complications and two for hemoperitoneum. Five patients had recurrent admissions for adhesion colic, which resolved with nonsurgical therapy. Ten patients succumbed on follow-up, six to tumor recurrence, two to unrelated cancers (stomach and bladder), and three to medical conditions.
  
  
  CONCLUSIONS
  The functional outcome of ileorectal anastomosis is generally rated as good to excellent by patients. Acceptable bowel function and control is regained within six months of the operation and levels off at one year after surgery, and no patient requires long-term antidiarrheal medication.
authors.affiliation: Department of Colorectal Surgery, Singapore General Hospital, Singapore.
authors.forename: K W
authors.initials: KW
authors.lastname: Eu
authors.forename: S L
authors.initials: SL
authors.lastname: Lim
authors.forename: F
authors.initials: F
authors.lastname: Seow-Choen
authors.forename: A F
authors.initials: AF
authors.lastname: Leong
authors.forename: Y H
authors.initials: YH
authors.lastname: Ho
mesh_terms: D011125:Adenomatous Polyposis Coli / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical; D000930:Antidiarrheals / Q000627:therapeutic use; D003082:Colectomy / Q000401:mortality; D003106:Colon / Q000601:surgery*; D003110:Colonic Neoplasms / Q000601:surgery; D003672:Defecation / Q000502:physiology; D004241:Diverticulum, Colon / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007082:Ileum / Q000601:surgery*; D007415:Intestinal Obstruction / Q000209:etiology; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D010528:Peristalsis / Q000502:physiology; D011183:Postoperative Complications; D012007:Rectum / Q000601:surgery*; D012086:Reoperation; D016896:Treatment Outcome
chemical_list: D000930:Antidiarrheals