title: Defining the maximum tolerated dose: investigator, academic, industry and regulatory perspectives.
authors.affiliation: Tufts University School of Medicine, Boston, Massachusetts, USA.
authors.forename: N R
authors.initials: NR
authors.lastname: Cutler
authors.forename: J J
authors.initials: JJ
authors.lastname: Sramek
authors.forename: D J
authors.initials: DJ
authors.lastname: Greenblatt
authors.forename: P
authors.initials: P
authors.lastname: Chaikin
authors.forename: N
authors.initials: N
authors.lastname: Ford
authors.forename: L J
authors.initials: LJ
authors.lastname: Lesko
authors.forename: B
authors.initials: B
authors.lastname: Davis
authors.forename: R L
authors.initials: RL
authors.lastname: Williams
mesh_terms: D000818:Animals; D002986:Clinical Trials as Topic; D004305:Dose-Response Relationship, Drug; D004345:Drug Industry; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D012107:Research Design; D014481:United States; D014486:United States Food and Drug Administration