Two new cases of near-tetraploidy in adult acute myeloid leukemia.
Tetraploid or near-tetraploid karyotype has been described rarely in hematologic neoplasms. Herein we report two new cases of adult acute myeloblastic leukemia, M0 and M1 FAB subtypes that showed near-tetraploid clones that were studied with conventional cytogenetics and in situ hybridization (ISH). We compare our new cases with those previously reported.
Espinet
B
B
Laboratori de Citologia Hematològica, Hospital Central l'Aliança, Barcelona, Spain.
Solé
F
F
Woessner
S
S
Florensa
L
L
Besses
C
C
Sans-Sabrafen
J
J
D000368:Aged; D000369:Aged, 80 and over; D000782:Aneuploidy; D006801:Humans; D016130:Immunophenotyping; D017403:In Situ Hybridization; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D008875:Middle Aged