Inflammatory acne represents hypersensitivity to Propionibacterium acnes.
Hypersensitivity to P. acnes may account for the great variation in acne severity. Alternative explanations such as hyperandrogenism fail to account for disease severity in large numbers of patients.
Webster
G F
GF
Jefferson Medical College, Philadelphia, Pa., USA.
D000152:Acne Vulgaris / Q000097:blood / Q000276:immunology* / Q000382:microbiology / Q000473:pathology; D000728:Androgens / Q000097:blood; D000907:Antibodies, Bacterial / Q000032:analysis; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000150:complications*; D007249:Inflammation; D011425:Propionibacterium acnes / Q000276:immunology*
D000728:Androgens; D000907:Antibodies, Bacterial