title: [Pharma-Clinics. The drug of the month. Adapalene (Differin gel)].
abstract: Adapalene is a new topical retinoid derived from naphthoic acid with a selective effect on the epidermis. It is indicated for treatment of acne vulgaris, alone or with other antiacneic topicals. It displays comedolytic and anti-inflammatory activities. The only frequent adverse event is a mild skin irritation during the first two weeks of treatment.
authors.affiliation: Université de Liège, Service de Dermatologie.
authors.forename: C
authors.initials: C
authors.lastname: Bonardeaux
authors.forename: M
authors.initials: M
authors.lastname: de la Brassinne
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy; D000068816:Adapalene; D000279:Administration, Cutaneous; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D004338:Drug Combinations; D006801:Humans; D007509:Irritants / Q000009:adverse effects; D009281:Naphthalenes / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D012176:Retinoids / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D012867:Skin / Q000187:drug effects; D013997:Time Factors
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D003879:Dermatologic Agents; D004338:Drug Combinations; D007509:Irritants; D009281:Naphthalenes; D012176:Retinoids; D000068816:Adapalene