title: Propofol anesthesia in a patient with Isaacs syndrome--report of a case and literature review.
abstract: Isaacs syndrome is an unusual lower motor neuron disease characterized by myokymia (muscle twitching), muscular stiffness, and decreased tendon reflexes. We reported a patient who was affected with this rare disease, with manifestation of involuntary muscular contractions and required general anesthesia for bilateral tonsillectomies. Understanding the presentation and characterization of this unusual disease may be helpful in making choice of anesthetics or anesthetic techniques. Its possible mechanisms of action and its specific considerations in anesthesia in the literature are reviewed and discussed.
authors.affiliation: Department of Anaesthesia, Chang Gung Memorial Hospital, Taoyuan, Taiwan, R.O.C.
authors.forename: M H
authors.initials: MH
authors.lastname: Shyr
authors.forename: A C
authors.initials: AC
authors.lastname: Ho
authors.forename: C C
authors.initials: CC
authors.lastname: Lin
authors.forename: K Y
authors.initials: KY
authors.lastname: Hsu
authors.forename: C H
authors.initials: CH
authors.lastname: Yang
authors.forename: C H
authors.initials: CH
authors.lastname: Chen
mesh_terms: D000328:Adult; D000771:Anesthesia, Intravenous / Q000379:methods*; D018686:Anesthetics, Intravenous / Q000494:pharmacology*; D005207:Fasciculation / Q000150:complications*; D006801:Humans; D008297:Male; D015742:Propofol / Q000494:pharmacology*
chemical_list: D018686:Anesthetics, Intravenous; D015742:Propofol