title: Cutaneous polyarteritis nodosa in a child and a review of the literature.
abstract: The cutaneous form of polyarteritis nodosa in children is extremely rare. Findings are usually limited to the skin, muscles and joints. It has a benign but often chronic course. We describe an 8-y-old girl with cutaneous PAN, with extensive livedo reticularis on lower and upper extremities, tender subcutaneous nodules, arthralgia and right ankle swelling. Skin biopsy revealed vasculitis of small and medium-sized blood vessels characterized by fibrinoid necrosis. The use of prednisolone resulted in clinical improvement initially, but recurrence occurred during tapering. She showed marked improvement with additional high dose methyl prednisolone monthly.
authors.affiliation: Department of Paediatrics, Faculty of Medicine, Karadeniz (Black Sea) Technical University, Trabzon, Turkey.
authors.forename: H
authors.initials: H
authors.lastname: Mocan
authors.forename: M C
authors.initials: MC
authors.lastname: Mocan
authors.forename: H
authors.initials: H
authors.lastname: Peru
authors.forename: Y
authors.initials: Y
authors.lastname: Ozoran
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001707:Biopsy, Needle; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007866:Leg; D009336:Necrosis; D010488:Polyarteritis Nodosa / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D011239:Prednisolone / Q000627:therapeutic use; D012867:Skin / Q000473:pathology
chemical_list: D000893:Anti-Inflammatory Agents; D011239:Prednisolone