Population genetics: surviving under mutation pressure.
Concern has been voiced about the survival of endangered species, and even the long-term prospects for humans, in the face of accumulating deleterious mutations. Two experiments have investigated the mutation accumulation process in laboratory Drosophila populations, with apparently conflicting results.
Keightley
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PD
Institute of Cell, Animal and Population Biology, University of Edinburgh, West Mains Road, Edinburgh, EH9 3JT, Scotland.
Caballero
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García-Dorado
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D000818:Animals; D004330:Drosophila / Q000235:genetics; D005260:Female; D005828:Genetics, Population; D006801:Humans; D008297:Male; D008957:Models, Genetic; D009154:Mutation; D012641:Selection, Genetic