title: Two new cases of near-tetraploidy in adult acute myeloid leukemia.
abstract: Tetraploid or near-tetraploid karyotype has been described rarely in hematologic neoplasms. Herein we report two new cases of adult acute myeloblastic leukemia, M0 and M1 FAB subtypes that showed near-tetraploid clones that were studied with conventional cytogenetics and in situ hybridization (ISH). We compare our new cases with those previously reported.
authors.affiliation: Laboratori de Citologia Hematològica, Hospital Central l'Aliança, Barcelona, Spain.
authors.forename: B
authors.initials: B
authors.lastname: Espinet
authors.forename: F
authors.initials: F
authors.lastname: Solé
authors.forename: S
authors.initials: S
authors.lastname: Woessner
authors.forename: L
authors.initials: L
authors.lastname: Florensa
authors.forename: C
authors.initials: C
authors.lastname: Besses
authors.forename: J
authors.initials: J
authors.lastname: Sans-Sabrafen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000782:Aneuploidy; D006801:Humans; D016130:Immunophenotyping; D017403:In Situ Hybridization; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D008875:Middle Aged