Treatment options for cirrhotic ascites.
Ascites due to cirrhosis can usually be managed successfully by dietary sodium restriction and carefully monitored diuretic therapy. However, paracentesis with an albumin infusion is a relatively safe alternative that has gained widespread acceptance. Other plasma expanders offer a cheaper alternative to albumin. Other recently developed techniques include peritoneovenous shunt and transjugular intrahepatic portosystemic stent shunt. Each of these is associated with an operative mortality and substantial complications, but for diuretic-resistant ascites a peritoneovenous shunt has comparable results to paracentesis/albumin. For patients with spontaneously occurring renal failure the prognosis is poor. None of the above treatments improves renal function. Management should therefore be symptomatic with paracentesis as necessary.
Wilkinson
S P
SP
Derriford Hospital, Plymouth, UK.
D001201:Ascites / Q000188:drug therapy / Q000601:surgery*; D004232:Diuretics / Q000627:therapeutic use; D006801:Humans; D008103:Liver Cirrhosis / Q000188:drug therapy / Q000601:surgery*; D019152:Paracentesis; D010536:Peritoneovenous Shunt; D011170:Portasystemic Shunt, Surgical
D004232:Diuretics