title: Crusted scabies of the scalp in dermatomyositis patients: three cases treated with oral ivermectin.
abstract: BACKGROUND
  Cutaneous features in the scalp area among adult patients are rarely considered as a manifestation of scabies.
  
  
  METHODS
  Three patients with clinical and laboratory data of dermatomyositis with scalp involvement (fulfill three or four of Bohan and Peter's criteria), of 4 years, 8 months, and 3 years duration, were seen at our department between 1995 and 1996. For relapses of ordinary scabies, they were treated repeatedly with local scabicide with temporary effect. After a symptom-free period during the treatment of dermatomyositis with corticosteroids and azathioprine, they developed diffuse redness with scales and crusts on the scalp areas. Light microscopy examination of material taken from these crusts showed an abundance of live mites.
  
  
  RESULTS
  All patients were successfully cured of scabies with a twice oral dose of 200 microg/kg ivermectin within 8 days.
  
  
  CONCLUSIONS
  Our patients with crusted scabies of the scalp and dermatomyositis prompted us to change our standard diagnostic and therapeutic regimens. Fascinating features included mimicry of scabies in patients with dermatomyositis, location of parasites on the scalp, suppressed cell-mediated immunity and successful cure of mange by ivermectin.
authors.affiliation: Department of Dermatology and Venereology, University of Medicine, Sofia, Bulgaria.
authors.forename: A L
authors.initials: AL
authors.lastname: Dourmishev
authors.forename: D K
authors.initials: DK
authors.lastname: Serafimova
authors.forename: L A
authors.initials: LA
authors.lastname: Dourmishev
authors.forename: M A
authors.initials: MA
authors.lastname: Mualla
authors.forename: V
authors.initials: V
authors.lastname: Papaharalambous
authors.forename: T
authors.initials: T
authors.lastname: Malchevsky
mesh_terms: D000328:Adult; D000368:Aged; D003882:Dermatomyositis / Q000150:complications*; D005260:Female; D006801:Humans; D007306:Insecticides / Q000627:therapeutic use*; D007559:Ivermectin / Q000627:therapeutic use*; D012532:Scabies / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D012536:Scalp Dermatoses / Q000150:complications / Q000469:parasitology* / Q000473:pathology
chemical_list: D007306:Insecticides; D007559:Ivermectin