Oxygen radicals and signaling.
Recent evidence suggests that reactive oxygen species, such as superoxide anions and hydrogen peroxide, function as intracellular second messengers. This review will discuss the progress in understanding the intracellular pathways leading from ligand stimulation to the generation of oxidants, as well as some of the increasing number of cellular processes that appear to be subject to redox regulation.
Finkel
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Cardiology Branch, National Institutes of Health, Bethesda, MD 20892-1650, USA.
D000818:Animals; D006801:Humans; D008954:Models, Biological; D017382:Reactive Oxygen Species / Q000378:metabolism* / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*
D017382:Reactive Oxygen Species