Conservative management of superior mesenteric and portal vein thrombosis associated with protein C and S deficiency. Case report.
Protein C and S, vitamin K-dependent proteins, are blood coagulation inhibitors. Their deficiency causes systemic thrombosis. A 35-year-old man who developed superior mesenteric venous thrombosis and portal vein thrombosis showed markedly decreased protein C and S levels. The therapeutic modality of this thrombosis associated with protein C and S deficiency is still debated. We treated this patient with systemic anticoagulation and long term total parenteral nutrition without surgical intervention.
Kim
D I
DI
Department of General Surgery, Samsung Medical Center, Seoul, Korea.
Lee
B B
BB
Noh
S I
SI
Baek
Y H
YH
Joh
J W
JW
Lee
S K
SK
Kim
Y I
YI
D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008642:Mesenteric Veins; D010288:Parenteral Nutrition; D011169:Portal Vein; D011172:Portography; D020151:Protein C Deficiency; D018455:Protein S Deficiency / Q000097:blood / Q000150:complications* / Q000628:therapy; D013927:Thrombosis / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy*; D014057:Tomography, X-Ray Computed
D000925:Anticoagulants