title: The discovery of LY293111, a novel, potent and orally active leukotriene B4 receptor antagonist of the biphenylphenol class.
authors.affiliation: Lilly Research Labs, Eli Lilly and Co., Indianapolis, IN 46285, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Sofia
authors.forename: P
authors.initials: P
authors.lastname: Floreancig
authors.forename: N
authors.initials: N
authors.lastname: Bach
authors.forename: S R
authors.initials: SR
authors.lastname: Baker
authors.forename: K
authors.initials: K
authors.lastname: Nelson
authors.forename: J S
authors.initials: JS
authors.lastname: Sawyer
authors.forename: R
authors.initials: R
authors.lastname: Baldwin
authors.forename: S L
authors.initials: SL
authors.lastname: Cockerham
authors.forename: J H
authors.initials: JH
authors.lastname: Fleisch
authors.forename: L L
authors.initials: LL
authors.lastname: Froelich
authors.forename: W T
authors.initials: WT
authors.lastname: Jackson
authors.forename: P
authors.initials: P
authors.lastname: Marder
authors.forename: C R
authors.initials: CR
authors.lastname: Roman
authors.forename: D L
authors.initials: DL
authors.lastname: Saussy
authors.forename: S A
authors.initials: SA
authors.lastname: Silbaugh
authors.forename: S M
authors.initials: SM
authors.lastname: Spaethe
authors.forename: P W
authors.initials: PW
authors.lastname: Stengel
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001565:Benzoates / Q000008:administration & dosage / Q000494:pharmacology*; D016084:Bronchoconstriction / Q000187:drug effects; D002462:Cell Membrane / Q000378:metabolism; D006168:Guinea Pigs; D006801:Humans; D007975:Leukotriene B4 / Q000494:pharmacology; D008168:Lung / Q000502:physiology*; D009504:Neutrophils / Q000187:drug effects / Q000502:physiology*; D010636:Phenols / Q000494:pharmacology*; D018102:Receptors, Leukotriene B4 / Q000037:antagonists & inhibitors / Q000378:metabolism*; D013329:Structure-Activity Relationship
chemical_list: D001565:Benzoates; C094099:LY 293111; D010636:Phenols; D018102:Receptors, Leukotriene B4; D007975:Leukotriene B4