title: Conduction aphasia in a 3-year-old with a left posterior cortical/subcortical abscess.
abstract: A 3-year-old, right-handed girl developed a conduction-type aphasia following a second generalized seizure in the setting of a developing abscess involving left subcortical and cortical angular gyrus and arcuate fasciculus, and the posterior corpus callosum. The language disorder was fluent, characterized by age appropriate mean length of utterance and syntax, but with markedly reduced spontaneity of output, rapid rate of speech and mild dysarthria. Comprehension was relatively, but not completely spared. Naming, repetition, and reading (letters) were initially markedly impaired. Improvements in naming and repetition were associated with both literal and semantic paraphasias. Writing skills in the form of drawing were spared, but a mild apraxia to verbal command and imitation was initially present. Despite her young age, this child's fluent conduction aphasia and lesion localization were adult-like. Multimodal memory difficulties appeared to underlie what is best described as conduction aphasia.
authors.affiliation: New York University Medical Center, Department of Neurology, NY 10016, USA.
authors.forename: R
authors.initials: R
authors.lastname: Nass
authors.forename: F
authors.initials: F
authors.lastname: Leventhal
authors.forename: B
authors.initials: B
authors.lastname: Levine
authors.forename: D
authors.initials: D
authors.lastname: Lebron
authors.forename: C
authors.initials: C
authors.lastname: Maxfield
authors.forename: P
authors.initials: P
authors.lastname: McCaul
authors.forename: A
authors.initials: A
authors.lastname: George
authors.forename: J
authors.initials: J
authors.lastname: Allen
mesh_terms: D000038:Abscess / Q000150:complications / Q000175:diagnosis*; D001037:Aphasia / Q000175:diagnosis / Q000209:etiology*; D002277:Carcinoma / Q000150:complications / Q000175:diagnosis; D002552:Cerebral Ventricles / Q000473:pathology*; D002675:Child, Preschool; D016545:Choroid Plexus Neoplasms / Q000150:complications / Q000175:diagnosis; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009483:Neuropsychological Tests; D014057:Tomography, X-Ray Computed