title: Down syndrome associated malformations.
abstract: This paper reports the associated malformations and the clinical findings that were observed in 417 cytogenetically confirmed Down Syndrome patients. Among them congenital heart defects have occurred more frequently [75; 17.98%] than osteoarticular malformations [23; 5.52]; eye anomalies [22; 5.27%]; and gastroenterological malformations [n 16; 3.84%]. With regard to prognosis and treatment appropriate counselling has been given to Down Syndrome patients and their families.
authors.affiliation: Dept. of Anatomy, St. John's Medical College, Bangalore.
authors.forename: S
authors.initials: S
authors.lastname: Rajangam
authors.forename: S
authors.initials: S
authors.lastname: Hegde
authors.forename: I M
authors.initials: IM
authors.lastname: Thomas
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004065:Digestive System Abnormalities / Q000000981:diagnostic imaging / Q000453:epidemiology*; D004314:Down Syndrome / Q000000981:diagnostic imaging / Q000453:epidemiology*; D005124:Eye Abnormalities / Q000000981:diagnostic imaging / Q000453:epidemiology*; D005260:Female; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009139:Musculoskeletal Abnormalities / Q000000981:diagnostic imaging / Q000453:epidemiology*; D011859:Radiography; D015619:Respiratory System Abnormalities / Q000000981:diagnostic imaging / Q000453:epidemiology*; D012189:Retrospective Studies; D017678:Sex Distribution