Analysis and design of three-stranded coiled coils and three-helix bundles.
Three-stranded coiled coils and three-helix bundles are increasingly being identified in proteins. Design and engineering on the scaffolds of these motifs is a potential route towards combating associated viral infections as well as introducing novel functional sites.
Schneider
J P
JP
Johnson Research Foundation, Department of Biochemistry and Biophysics, University of Pennsylvania, Philadelphia 19104-6059, USA.
Lombardi
A
A
DeGrado
W F
WF
D001665:Binding Sites; D002352:Carrier Proteins / Q000737:chemistry; D037102:Lectins / Q000737:chemistry; D037241:Mannose-Binding Lectins; D008958:Models, Molecular; D011487:Protein Conformation; D017510:Protein Folding; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry*; D014759:Viral Envelope Proteins / Q000737:chemistry
D002352:Carrier Proteins; D037102:Lectins; D037241:Mannose-Binding Lectins; D011506:Proteins; D014759:Viral Envelope Proteins