title: Depressive symptoms in adult coeliac disease.
abstract: BACKGROUND
  Psychic symptoms and depression have been reported in coeliac disease (CD). The aim of this study was to explore depression in a large cohort of adult CD patients.
  
  
  METHODS
  Depressive symptoms were evaluated in 92 adult coeliacs, 100 normal controls (NC), and 48 chronic persistent hepatitis (CPH) patients by means of a modified version of the Zung Self-Rating Depression Scale (M-SDS). CD patients were evaluated for the level of knowledge about CD and the compliance with diet.
  
  
  RESULTS
  The M-SDS score differentiated CD patients from NC. Age at diagnosis and duration of and compliance with diet did not correlate with depression. Three main factors could be identified with the M-SDS: 'reactiveness', 'pessimism', and 'anhedonic-asthenic'.
  
  
  CONCLUSIONS
  Depressive symptoms are a feature of CD; they are present to a similar extent in patients with childhood- and adulthood-diagnosed CD. The results underline the relevance of personal psychologic resources, which play a fundamental role in determining and sustaining depression.
authors.affiliation: Dept. of Gastroenterology, University of Naples Federico II, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Ciacci
authors.forename: A
authors.initials: A
authors.lastname: Iavarone
authors.forename: G
authors.initials: G
authors.lastname: Mazzacca
authors.forename: A
authors.initials: A
authors.lastname: De Rosa
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D002446:Celiac Disease / Q000523:psychology*; D003863:Depression / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D011581:Psychological Tests