Eicosanoid 12(S)-HETE upregulates endothelial cell alpha V beta 3 integrin expression and promotes tumor cell adhesion to vascular endothelium.
Honn
K V
KV
Department of Radiation Oncology, Wayne State University, Detroit, MI 48202, USA.
Tang
D G
DG
D019377:12-Hydroxy-5,8,10,14-eicosatetraenoic Acid / Q000494:pharmacology*; D000818:Animals; D002448:Cell Adhesion / Q000187:drug effects / Q000502:physiology*; D004730:Endothelium, Vascular / Q000187:drug effects / Q000502:physiology / Q000503:physiopathology*; D006801:Humans; D009362:Neoplasm Metastasis; D009369:Neoplasms / Q000473:pathology / Q000503:physiopathology*; D019030:Receptors, Vitronectin / Q000096:biosynthesis*; D014158:Transcription, Genetic / Q000187:drug effects; D015854:Up-Regulation / Q000187:drug effects
D019030:Receptors, Vitronectin; D019377:12-Hydroxy-5,8,10,14-eicosatetraenoic Acid