title: Studies on plasmepsins I and II from the malarial parasite Plasmodium falciparum and their exploitation as drug targets.
authors.affiliation: F. Hoffmann-La Roche, Pharmaceuticals Division, Pharma Research Pre-Clinical, Basel, Switzerland.
authors.forename: R P
authors.initials: RP
authors.lastname: Moon
authors.forename: D
authors.initials: D
authors.lastname: Bur
authors.forename: H
authors.initials: H
authors.lastname: Loetscher
authors.forename: A
authors.initials: A
authors.lastname: D'Arcy
authors.forename: L
authors.initials: L
authors.lastname: Tyas
authors.forename: C
authors.initials: C
authors.lastname: Oefner
authors.forename: F
authors.initials: F
authors.lastname: Grueninger-Leitch
authors.forename: D
authors.initials: D
authors.lastname: Mona
authors.forename: K
authors.initials: K
authors.lastname: Rupp
authors.forename: A
authors.initials: A
authors.lastname: Dorn
authors.forename: H
authors.initials: H
authors.lastname: Matile
authors.forename: U
authors.initials: U
authors.lastname: Certa
authors.forename: C
authors.initials: C
authors.lastname: Berry
authors.forename: J
authors.initials: J
authors.lastname: Kay
authors.forename: R G
authors.initials: RG
authors.lastname: Ridley
mesh_terms: D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D016282:Aspartic Acid Endopeptidases / Q000037:antagonists & inhibitors / Q000235:genetics / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D010963:Plasmodium falciparum / Q000187:drug effects / Q000201:enzymology* / Q000254:growth & development; D015800:Protozoan Proteins
chemical_list: D000962:Antimalarials; D004791:Enzyme Inhibitors; D006454:Hemoglobins; D015800:Protozoan Proteins; D016282:Aspartic Acid Endopeptidases; C089643:plasmepsin; C100637:plasmepsin II