Histologic findings of transmyocardial laser channels after two hours.
Histologic examination of the human myocardium has been performed several days, weeks, and months after transmyocardial laser revascularization. We performed microscopic examinations 2 hours postoperatively. In addition to the patent channel (diameter, 1 mm) and a 1-to 2-mm rim of necrosis, a 1- to 3-mm zone of myofibrillary degeneration was found. This additional reversible injury immediately after transmyocardial laser revascularization could explain the higher mortality rate in patients with reduced left ventricular function.
Lutter
G
G
Department of Cardiovascular Surgery, University of Freiburg, Germany. lutter@ch11.ukl.uni-freiburg.de
Schwarzkopf
J
J
Lutz
C
C
Martin
J
J
Beyersdorf
F
F
D000368:Aged; D001145:Arrhythmias, Cardiac / Q000209:etiology; D002303:Cardiac Output, Low / Q000209:etiology; D004489:Edema, Cardiac / Q000473:pathology; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D009204:Myocardial Revascularization / Q000379:methods*; D009206:Myocardium / Q000473:pathology*; D009210:Myofibrils / Q000648:ultrastructure; D009336:Necrosis; D015996:Survival Rate; D014654:Vascular Patency; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000601:surgery