title: [Spherical crystallization in pharmaceutical technology].
abstract: Physical properties of crystals, such as size, crystal size distribution and morphology, may predetermine the usefulness of crystalline materials in many pharmaceutical application. The above properties can be regulated with the crystallization process. The spherical crystals are suitable for direct tablet-making because of their better flowability and compressibility properties. These crystals can be used in the filling of the capsule. In this work, the spherical crystals such as "single crystal", "poly-crystals" and agglomerates with other excipients are collected from the literature and the experimental results of the authors. A close cooperation between chemists and the pharmaceutical technologists can help for doing steps in this field.
authors.affiliation: Szent-Györgyi Albert Orvostudományi Egyetem, Gyógyszertechnológiai Intézet, Szeged.
authors.forename: R P
authors.initials: RP
authors.lastname: Szabóné
authors.forename: H K
authors.initials: HK
authors.lastname: Pintyéné
authors.forename: P
authors.initials: P
authors.lastname: Kása
authors.forename: I
authors.initials: I
authors.lastname: Erös
authors.forename: N M
authors.initials: NM
authors.lastname: Hasznosné
authors.forename: B
authors.initials: B
authors.lastname: Farkas
mesh_terms: D002627:Chemistry, Physical / Q000379:methods; D003460:Crystallization; D004364:Pharmaceutical Preparations
chemical_list: D004364:Pharmaceutical Preparations
vernacular_title: A szférikus kristályosítás gyógyszertechnológiai vonatkozásai.