[Intracytoplasmic sperm injection in the management of male infertility and idiopathic fertilization failure].
OBJECTIVE
To demonstrate the efficacy of intracytoplasmic sperm injection (ICSI) in treatment male infertility and idiopathic fertilization failure.


METHODS
31 couples received intracytoplasmic sperm injections because of severe oligo-astheno-teratospermia or idiopathic infertility. Ovarian stimulation was achieved by conventional protocol. Transvaginal ultrasound-guided oocyte collections were done 36 hours after hCG injection. Only matured oocytes were selected for microinjection.


RESULTS
237 oocytes were treated by intracytoplasmic sperm injection; normal fertilization and cleavage occurred in 132 of 213 oocytes which were survived (62.0% normal fertilization rate). From 1995 to 1996, clinical pregnancies were achieved in 8 cases (25.8%). The first ICSI baby was delivered on October 3, 1996.


CONCLUSIONS
Intracytoplasmic sperm injection has improved the results of IVF-ET treatment in male and idiopathic infertility.
Li
R
R
Assisted Reproductive Technique Center, First Affiliated Hospital of Sun Yet-Sen University of Medical Sciences, Guangzhou.
Zhuang
G
G
Zhang
M
M
D000328:Adult; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D007248:Infertility, Male / Q000628:therapy*; D008297:Male; D008845:Microinjections; D009865:Oocytes; D013094:Spermatozoa