title: Microvenular hemangioma.
abstract: A case of microvenular hemangioma in a 23-year-old Japanese female is described. The patient presented with a slowly growing, solitary reddish plague on her back, which measured 15 x 17 mm. Histologically, the tumor was an infiltrative growth throughout the dermis. It consisted of thin-walled, small-sized, irregularly branched vascular vessels. The vascular lumina were narrow. The flattened endothelial cells had oval to spindle-shaped nuclei and scant cytoplasm that were immunohistochemically positive for endothelial markers. The tumor cells lacked cellular atypia, pleomorphism, and mitotic figures. The patient was well without disease 8 months after the excision. Pathologists and clinicians should be aware of the existence of this type of hemangioma with an infiltrative growth and avoid overdiagnosis and overtreatment.
authors.affiliation: Department of Pathology, Jikei University School of Medicine, Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Fukunaga
authors.forename: S
authors.initials: S
authors.lastname: Ushigome
mesh_terms: D000199:Actins / Q000378:metabolism; D000328:Adult; D014408:Biomarkers, Tumor / Q000378:metabolism; D005260:Female; D006391:Hemangioma / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D012878:Skin Neoplasms / Q000378:metabolism / Q000473:pathology*; D014699:Venules; D014841:von Willebrand Factor / Q000378:metabolism
chemical_list: D000199:Actins; D014408:Biomarkers, Tumor; D014841:von Willebrand Factor