title: Fibula grafting for treatment of aggressive benign bone tumor and malignant bone tumor of extremities.
abstract: OBJECTIVE
  To compare the effect of vascularized and nonvascularized fibula grafting performed for the reconstruction of bone defects after the resection of bone tumors.
  
  
  METHODS
  Vascularized fibula grafting was performed in 18 patients with malignant or aggressive benign bone tumor of the extremities. Non-vascularized fibula grafting was performed in 15 patients with giant cell tumor of the radius. All the 18 patients were followed up with radiography, single photon emission computed tomography (SPECT), colored Doppler's sonography (CDS) examinations and functional observation for 2 to 14 years.
  
  
  RESULTS
  Vascularized fibula grafts with bone defects of 9 to 26 cm showed good blood supply in emission computerized tomography (ECT) and radiography examinations, and bone union was achieved (Table 1). In non-vascularized fibula grafting cases (Table 2), bone union was not achieved.
  
  
  CONCLUSIONS
  The advantages of vascularized grafting are the feasibility of one-stage reconstruction of various tissues and the growth of grafted fibula. It is necessary to adopt vascularized fibula grafting to reconstruct large bone defect resulting from the resection of extensive bone tumors, such as giant cell tumor (GCT), fibrous dysplasia of bone and malignant bone tumors.
authors.affiliation: Department of Orthopaedics, Zhong Shan Hospital, Shanghai Medical University, China.
authors.forename: Z
authors.initials: Z
authors.lastname: Chen
authors.forename: Z
authors.initials: Z
authors.lastname: Chen
authors.forename: G
authors.initials: G
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000601:surgery*; D005121:Extremities / Q000601:surgery; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000601:surgery*; D005360:Fibula / Q000098:blood supply / Q000637:transplantation*; D005500:Follow-Up Studies; D018212:Giant Cell Tumor of Bone / Q000601:surgery*; D018219:Histiocytoma, Benign Fibrous / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011884:Radius / Q000601:surgery; D015899:Tomography, Emission-Computed, Single-Photon; D014945:Wound Healing