[A prospective study on post-transfusion hepatitis C].
A cooperative prospective study on the clinical epidemiology of post-transfusion hepatitis C virus (HCV) infection was carried out from April 1993 to November 1994 in four medical schools in China, namely, Peking Union Medical College (PUMC), Western China Medical University (WCMU), Shanghai Medical University (SMU) and Beijing Medical University (BMU). A screen test on anti-HCV was done for the healthy donors of four groups. Anti-HCV positive rate was found to be 14.49% in professional blood donors, 5.60% in rural donors and 0.42% in urban volunteer donors. The positive rate of anti-HCV in blood recipients followed more than three months after transfusion was quite different in the four institutes, being 15.34% (14/91) in PUMC, 24.59% (15/61) in WCMU, 13.18% (12/91) in SMU and 1.53% (1/65) in BMU. During the same period post-transfusion hepatitis B virus infection rate decreased as compared with that in the past. It is concluded that the screen test on anti-HCV in blood donors can not completely rule out post-transfusion HCV infection.
Wang
A
A
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing.
Sheng
R
R
D001782:Blood Donors; D001803:Blood Transfusion; D002681:China / Q000453:epidemiology; D006526:Hepatitis C / Q000453:epidemiology / Q000635:transmission*; D018937:Hepatitis C Antibodies / Q000097:blood; D006801:Humans; D015994:Incidence; D011446:Prospective Studies
D018937:Hepatitis C Antibodies