Cytotoxic compounds from the roots of Juglans mandshurica.
Three new compounds, a diarylheptanone glucoside (1), 4,5, 8-trihydroxy-alpha-tetralone 5-O-beta-d-[6'-O-(3", 5"-dimethoxy-4"-hydroxybenzoyl)]glucopyranoside (2), and 1,4, 8-trihydroxy-3-naphthalenecarboxylic acid 1-O-beta-d-glucopyranoside methyl ester (3), were isolated from the roots of Juglans mandshurica, and their structures were elucidated on the basis of spectroscopic studies including 2D-NMR.
Kim
S H
SH
College of Pharmacy, Yeungnam University, Gyongsan 712-749, Korea.
Lee
K S
KS
Son
J K
JK
Je
G H
GH
Lee
J S
JS
Lee
C H
CH
Cheong
C J
CJ
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification*; D001952:Bridged-Ring Compounds / Q000737:chemistry / Q000302:isolation & purification*; D036381:Diarylheptanoids; D004354:Drug Screening Assays, Antitumor; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D006801:Humans; D009281:Naphthalenes / Q000737:chemistry / Q000302:isolation & purification*; D018517:Plant Roots / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D013057:Spectrum Analysis; D044024:Tetralones; D014407:Tumor Cells, Cultured
C112721:1,4,8-trihydroxy-3-naphthalenecarboxylic acid 1-O-glucopyranoside methyl ester; C112720:4,5,8-trihydroxy-alpha-tetralone 5-O-(6'-O-(3'',5''-dimethoxy-4''-hydroxybenzoyl))glucopyranoside; D000972:Antineoplastic Agents, Phytogenic; D001952:Bridged-Ring Compounds; D036381:Diarylheptanoids; D005960:Glucosides; D009281:Naphthalenes; D044024:Tetralones; C112722:diarylheptanone glucoside I