title: [Combined surgical treatment of pulmonary neoplasms with single brain metastasis].
abstract: The combined surgical treatment of primitive lung cancer with single brain metastasis is a frequently debated but still controversial problem. Up to day several therapeutic approaches are generally integrated (surgery, radiotherapy, chemotherapy) according to the clinical patterns and the technical possibilities. In general, the combined surgical operation (thoracotomy + craniotomy) when it is possible to be done, followed or proceeded by chemo-radiotherapy, has allowed to achieve a prolonged survival in these patients, maintaining an acceptable quality of life. The authors analyze 10 cases treated by thoracotomy and craniotomy at the Chair of Thoracic Surgery of University of L'Aquila. Although consisting of a small number of cases, this experience allows to detect the particular problems concerning these patients. The indications to the combined surgical treatment are considered, evaluating the surgical operation which is to be performed as first on the basis of lung cancer staging and of the location and size of the brain metastases. Finally the patients survival and their quality of life are considered.
authors.affiliation: Università degli Studi de L'Aquila, Cattedra di Chirurgia Toracica.
authors.forename: G
authors.initials: G
authors.lastname: Torresini
authors.forename: R
authors.initials: R
authors.lastname: Crisci
authors.forename: A
authors.initials: A
authors.lastname: Lococo
authors.forename: M
authors.initials: M
authors.lastname: Cardelli
authors.forename: L
authors.initials: L
authors.lastname: Giusti
authors.forename: R J
authors.initials: RJ
authors.lastname: Galzio
authors.forename: G F
authors.initials: GF
authors.lastname: Coloni
mesh_terms: D000230:Adenocarcinoma / Q000401:mortality / Q000556:secondary / Q000601:surgery; D000368:Aged; D001932:Brain Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000556:secondary / Q000601:surgery; D002423:Cause of Death; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged
vernacular_title: Trattamento chirurgico combinato delle neoplasie polmonari con metastasi cerebrale unica.