title: Primary hepatic malignant fibrous histiocytoma: report of a case and review of the literature.
abstract: Malignant fibrous histiocytoma (MFH) is a common sarcoma of adulthood, frequently arising in the extremities, but also in the abdomen and the retroperitoneum. Primary MFH of the liver, however, remains extremely rare and is one of the least diagnosed primary hepatic sarcoma. Another case of primary MFH of the liver is reported. The patient presented with a 12 cm mass involving the right and left lobes of the liver. The histopathologic examination revealed a typical MFH swirling (storiform) pattern composed of atypical spindle and giant cells. The radiologic, histologic, and clinical behavior of this rare neoplasm are reviewed.
authors.affiliation: Department of Pathology and Laboratory Medicine, College of Medicine, University of Florida, Gainesville 32603-0275, USA.
authors.forename: S
authors.initials: S
authors.lastname: Fujita
authors.forename: G Y
authors.initials: GY
authors.lastname: Lauwers
mesh_terms: D000368:Aged; D000792:Angiography; D014408:Biomarkers, Tumor / Q000378:metabolism; D017809:Fatal Outcome; D018219:Histiocytoma, Benign Fibrous / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008113:Liver Neoplasms / Q000378:metabolism / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D000514:alpha 1-Antichymotrypsin / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; D000514:alpha 1-Antichymotrypsin