title: [New means for the prophylaxis of colon cancer with the use of beta-glucuronidase inhibitors].
abstract: Experiments involving the use of 1,2-dimethylhydrazine-induced colonic tumors in rats showed long-term treatment with a newly synthesized drug EDE-10g to inhibit an enzyme of enteric beta-glucuronidase, to suppress carcinogenesis and to prolong lifespan of animals.
authors.affiliation: N.N. Petrov Research Institute of Oncology, Ministry of Health of the RF, St. Petersburg.
authors.forename: G B
authors.initials: GB
authors.lastname: Pliss
authors.forename: N N
authors.initials: NN
authors.lastname: Vlasov
authors.forename: I V
authors.initials: IV
authors.lastname: Anikin
mesh_terms: D019813:1,2-Dimethylhydrazine; D000818:Animals; D016588:Anticarcinogenic Agents / Q000494:pharmacology*; D003110:Colonic Neoplasms / Q000139:chemically induced / Q000201:enzymology* / Q000473:pathology / Q000517:prevention & control*; D004195:Disease Models, Animal; D005966:Glucuronidase / Q000037:antagonists & inhibitors*; D008297:Male; D051381:Rats; D016019:Survival Analysis
chemical_list: D016588:Anticarcinogenic Agents; D005966:Glucuronidase; D019813:1,2-Dimethylhydrazine
vernacular_title: Novye vozmozhnosti profilaktiki raka kishechnika s ispol'zovaniem preparatov - ingibitorov beta-gliukuronidazy.