title: Stroke unit treatment improves long-term quality of life: a randomized controlled trial.
abstract: OBJECTIVE
  We have previously shown that treatment of acute stroke patients in the combined acute and rehabilitation stroke unit in our hospital improves survival and functional outcome compared with treatment in general wards. The primary aim of the present trial was to examine whether the treatment in our stroke unit had an effect on different aspects of quality of life (QoL) for stroke patients 5 years after the onset of stroke.
  
  
  METHODS
  In a randomized controlled trial, 110 patients with symptoms and signs of an acute stroke were allocated to the stroke unit and 110 to general wards. No significant differences existed in baseline characteristics between the two groups. The patients alive after 5 years were assessed by the Nottingham Health Profile (NHP) and the Frenchay Activities Index (FAI), which were the scales used as primary outcome measures for QoL. As secondary outcome measures we used a global score for the NHP and a simple visual analogue scale (VAS).
  
  
  RESULTS
  After 5 years, 45 of the patients treated in the stroke unit and 32 of those treated in general wards were alive. All surviving patients were assessed by the FAI. Thirty-seven (82.2%) of the stroke unit patients and 25 (78.1%) of the general wards patients were assessed by the NHP; 38 (84.4%) and 28 (87.5%), respectively, were assessed by the VAS. Patients treated in the stroke unit had a higher score on the FAI (P=0.0142). Assessment with the NHP showed better results in the stroke unit group for the dimensions of energy (P=0.0323), physical mobility (P=0.0415), emotional reactions (P=0.0290), social isolation (P=0.0089), and sleep (P=0.0436), although there was no difference in pain (P=0.3186). The global NHP score and VAS score also showed significantly better results in the stroke unit group (NHP, P<0.01; VAS, P<0.001). Patients who were independent in activities of daily living had significantly better QoL assessed by these scales than patients who were dependent.
  
  
  CONCLUSIONS
  Our study shows for the first time that stroke unit care improves different aspects of long-term QoL for stroke patients.
authors.affiliation: Department of Medicine, University Hospital of Trondheim, Norway.
authors.forename: B
authors.initials: B
authors.lastname: Indredavik
authors.forename: F
authors.initials: F
authors.lastname: Bakke
authors.forename: S A
authors.initials: SA
authors.lastname: Slørdahl
authors.forename: R
authors.initials: R
authors.lastname: Rokseth
authors.forename: L L
authors.initials: LL
authors.lastname: Håheim
mesh_terms: D000203:Activities of Daily Living; D002561:Cerebrovascular Disorders / Q000517:prevention & control / Q000534:rehabilitation / Q000628:therapy*; D003627:Data Interpretation, Statistical; D005500:Follow-Up Studies; D006304:Health Status; D006305:Health Status Indicators; D006757:Hospital Units; D006801:Humans; D010147:Pain Measurement / Q000592:standards; D011788:Quality of Life