title: Carbamazepine responsive epileptic oral motor and ocular motor apraxia.
abstract: We evaluated seven patients with oral motor apraxia and ocular motor apraxia. Apraxia in three patients (Group 1) with new-onset partial seizures and epileptiform discharges on EEG improved with carbamazepine. Four patients (Group 2) without seizures and nonepileptiform EEG findings had no change in apraxia after a trial of carbamazepine. Epileptic apraxia may precede clinical seizures and can respond to antiepileptic drugs.
authors.affiliation: Department of Neurology, University of North Carolina at Chapel Hill, 27599, USA.
authors.forename: S Z
authors.initials: SZ
authors.lastname: Naqvi
authors.forename: R S
authors.initials: RS
authors.lastname: Greenwood
authors.forename: O F
authors.initials: OF
authors.lastname: D'Cruz
mesh_terms: D000927:Anticonvulsants / Q000627:therapeutic use*; D001072:Apraxias / Q000150:complications / Q000188:drug therapy*; D002220:Carbamazepine / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D015835:Ocular Motility Disorders / Q000188:drug therapy* / Q000209:etiology; D011446:Prospective Studies; D011597:Psychomotor Performance / Q000187:drug effects*
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine