Malaria: dissecting chloroquine resistance.
The malaria parasite's development of resistance to the drug chloroquine is a major threat to world health. A protein likely to be involved in chloroquine resistance has recently been identified; this discovery is important, but raises as many questions as it answers.
Ridley
R G
RG
F. Hoffmann-La Roche, Basel, Switzerland. robert_g.ridley@roche.com
D000818:Animals; D000962:Antimalarials / Q000378:metabolism / Q000494:pharmacology*; D002738:Chloroquine / Q000378:metabolism / Q000494:pharmacology*; D004351:Drug Resistance / Q000235:genetics; D006801:Humans; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000235:genetics*; D015800:Protozoan Proteins / Q000235:genetics*
D000962:Antimalarials; C109422:CG2 protein, Plasmodium falciparum; D015800:Protozoan Proteins; D002738:Chloroquine