title: [Dynamics of spontaneous beating of cardiomyocytes in vitro depend on the number of involved cells].
abstract: The dynamics of cardiomyocyte spontaneous beatings with fractal dimension calculation was studied. It was shown that isolated single cardiomyocyte beats stochastically, but when a number of cells synchronized a significant changes in the dynamics appear: deterministic chaos could be detected. Several reasons are discussed as a possible explanation of such a behavior: the effect of system volume increasing and specific influence of gap-junctions on the rhythm formation.
authors.affiliation: Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow Region, Russia.
authors.forename: T R
authors.initials: TR
authors.lastname: Pzharskiĭ
authors.forename: A A
authors.initials: AA
authors.lastname: Sorokin
authors.forename: Iu A
authors.initials: IuA
authors.lastname: Rochev
authors.forename: B K
authors.initials: BK
authors.lastname: Gavriliuk
authors.forename: L M
authors.initials: LM
authors.lastname: Chaĭlakhian
mesh_terms: D000818:Animals; D002452:Cell Count; D006321:Heart / Q000502:physiology*; D008954:Models, Biological; D008962:Models, Theoretical; D009200:Myocardial Contraction; D009206:Myocardium / Q000166:cytology*; D051381:Rats; D017208:Rats, Wistar
vernacular_title: Izmenenie dinamiki sokrashcheniĭ kardiomiotsitov in vitro pri uvelichenii chisla vzaimodeĭstvuiushchikh kletok.