title: Reciprocal inhibition in forearm muscles in patients with essential tremor.
abstract: Reciprocal inhibition of the H-reflex in the forearm flexor muscles was studied in 11 patients with essential tremor and in 10 normal controls. Whereas patients and controls had a similar first, disynaptic phase of reciprocal inhibition, patients had a significantly reduced second phase. Patients with more severe functional impairment had more pronounced abnormalities of reciprocal inhibition. Abnormalities of reciprocal inhibition may play a role in the pathophysiology of essential tremor and probably arise from defective suprasegmental control.
authors.affiliation: Dipartimento di Scienze Neurologiche, Università degli studi di Roma La Sapienza, Rome, Italy.
authors.forename: B
authors.initials: B
authors.lastname: Mercuri
authors.forename: A
authors.initials: A
authors.lastname: Berardelli
authors.forename: N
authors.initials: N
authors.lastname: Modugno
authors.forename: L
authors.initials: L
authors.lastname: Vacca
authors.forename: S
authors.initials: S
authors.lastname: Ruggieri
authors.forename: M
authors.initials: M
authors.lastname: Manfredi
mesh_terms: D004576:Electromyography; D005542:Forearm / Q000503:physiopathology*; D006181:H-Reflex; D006801:Humans; D008875:Middle Aged; D009433:Neural Inhibition / Q000502:physiology*; D011826:Radial Nerve / Q000502:physiology; D014202:Tremor / Q000503:physiopathology*