[Evaluation of the quality of 2 techniques for measuring IgE: the Pharmacia CAP System (Pharmacia & Upjohn Diagnostics) and Alastat (DPC-France)].
The reliability of results given by specific IgE dosages technology is conditioned by the quality of the technology used. Analytical comparison of two techniques (Pharmacia CAP System and Alastat-DPC) shows important behaviour differences in the evaluation of the precision/reproducibility of results and in dilution tests. The Pharmacia CAP System demonstrates qualities comparable to those awaited from any immunodiagnostic test. The Alastat techniques shows high imprecision and the dilution tests make us wonder about calibration and/or ability of the support used to fix all epitopes.
Sabbah
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Laboratoires d'Immuno-Allergologie-C.H.U., Angers, France.
D000485:Allergens / Q000276:immunology; D000818:Animals; D002138:Calibration; D005069:Evaluation Studies as Topic; D005188:False Negative Reactions; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood*; D011786:Quality Control; D011852:Radioallergosorbent Test / Q000379:methods* / Q000592:standards; D011933:Reagent Kits, Diagnostic / Q000592:standards; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
D000485:Allergens; D011933:Reagent Kits, Diagnostic; D007073:Immunoglobulin E
Evaluation de la qualité de deux techniques de dosage d'IgE: Pharmacia CAP System (Pharmacia & Upjohn Diagnostics) et Alastat (DPC-France).