title: Invasive sino-nasal aspergillosis: a case report.
abstract: A case of invasive sino-nasal aspergillosis in an immunocompromised child is reported. Prognosis of this fulminant disease is usually poor. This paper reviews the early symptoms, clinical manifestations, risk factors, diagnosis and treatment. Awareness of the disease and early diagnosis by histological examination is essential. Treatment should consist of early administration of i.v. Amphotericin B and extensive surgical debridement.
authors.affiliation: Department of Otorhinolaryngology, Free University Brussels, Belgium.
authors.forename: K
authors.initials: K
authors.lastname: Hamels
authors.forename: F
authors.initials: F
authors.lastname: Gordts
authors.forename: J
authors.initials: J
authors.lastname: Ramet
mesh_terms: D000741:Anemia, Aplastic / Q000150:complications; D001228:Aspergillosis / Q000150:complications / Q000382:microbiology* / Q000473:pathology; D001231:Aspergillus flavus / Q000302:isolation & purification*; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005005:Ethmoid Sinus / Q000000981:diagnostic imaging / Q000382:microbiology*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007085:Ilium / Q000382:microbiology; D009297:Nasal Mucosa / Q000382:microbiology / Q000473:pathology; D009336:Necrosis; D014057:Tomography, X-Ray Computed