title: [Perioperative antibiotic prophylaxis in visceral surgery--pro and contra].
abstract: Perioperative antibiotic prophylaxis aims at reducing the enormous cost of hospital-acquired infections. Primary indications for antibiotic prophylaxis are wounds of the clean-contaminated and contaminated category. Use of antibiotic prophylaxis in clean surgery is still very controversial. To be effective, the antibiotic must be given in the period immediately before incision. A single-dose application is at least as effective as a multiple-dose regimen. Second-generation cephalosporins are still the main stay of antibiotic prophylaxis. In colorectal surgery they should be combined with, e.g., Metronidazol.
authors.affiliation: Chirurgische Universitätsklinik, RWTH Aachen.
authors.forename: R
authors.initials: R
authors.lastname: Kasperk
authors.forename: K P
authors.initials: KP
authors.lastname: Riesener
authors.forename: V
authors.initials: V
authors.lastname: Schumpelick
mesh_terms: D019072:Antibiotic Prophylaxis; D002511:Cephalosporins / Q000627:therapeutic use; D003428:Cross Infection / Q000382:microbiology / Q000517:prevention & control*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005767:Gastrointestinal Diseases / Q000382:microbiology / Q000601:surgery*; D006801:Humans; D008795:Metronidazole / Q000627:therapeutic use; D008826:Microbial Sensitivity Tests; D013530:Surgical Wound Infection / Q000382:microbiology / Q000517:prevention & control*; D016896:Treatment Outcome
chemical_list: D002511:Cephalosporins; D008795:Metronidazole
vernacular_title: Perioperative Antibiotikaprophylaxe in der Viszeralchirurgie--Pro und Contra.