title: An unusual localisation of Kaposi's sarcoma: the external auditory canal.
abstract: The epidemic form of Kaposi's sarcoma is associated with human immunodeficiency virus infection. Cutaneous and mucosal manifestations are frequently reported in the ENT sphere, mostly involving the oral cavity. The external and middle ear are only rarely concerned with only one case of a mastoid lesion without extension to the external auditory canal (EAC) being reported to this day. The present article describes the first case of involvement of the EAC with extension to adjacent structures. This patient presented other Kaposi lesions and had been treated by systemic hormonal therapy. Thereafter local injection of a cytotoxic agent was given without effect. Finally, radiotherapy resulted in a 50% regression of the tumour mass. The epidemiologic factors and therapeutic modalities with their results are described.
authors.affiliation: Department of Ear, Nose, Throat, Head and Neck Surgery, Université Libre de Bruxelles, Belgium.
authors.forename: C
authors.initials: C
authors.lastname: Delbrouck
authors.forename: S
authors.initials: S
authors.lastname: Kampouridis
authors.forename: G
authors.initials: G
authors.lastname: Chantrain
mesh_terms: D000328:Adult; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D002465:Cell Movement; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000627:therapeutic use; D004424:Ear Canal / Q000473:pathology* / Q000528:radiation effects; D004428:Ear Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D005682:Gadolinium; D006314:Hearing Loss, Conductive / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009361:Neoplasm Invasiveness; D016609:Neoplasms, Second Primary / Q000473:pathology; D010159:Palate / Q000473:pathology; D010610:Pharyngeal Neoplasms / Q000473:pathology; D011868:Radioisotopes; D012514:Sarcoma, Kaposi / Q000150:complications / Q000175:diagnosis* / Q000628:therapy; D014057:Tomography, X-Ray Computed; D014747:Vinblastine / Q000627:therapeutic use
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D018997:Chorionic Gonadotropin, beta Subunit, Human; D011868:Radioisotopes; D014747:Vinblastine; D005682:Gadolinium