title: [Use of a preparation of natural origin to attenuate biological effects under conditions of radioactive pollution and in a radiobiological experiment].
abstract: The experiments in animals exposed in the area of increased radiation level around the Chernobyl NPP and the observational data on laringosyndrom and peripheral blood pattern of the people, who worked at the Chernobyl NPP in 1986-1987, have shown that it is possible to use some biogenic preparations (e.g. MIGI-K) for protection under chronic exposure to natural and technogenous ionizing radiation. MIGI-K preparation effectively enhances radioresistance as well as general resistance of the organism. It has important positive characteristics: it is non-toxic, there are no side effects and contra-indications for its peroral use as a nutriceutic, it has no mutagenic properties, it has not only radioprophylactic but also radiotherapeutic activity and pronounced cancerostatic activity. It is also important that MIGI-K has long-term effects on the organism resistance (up to 2 weeks after the ending of its month course), enhances the endogenous background of radioresistance, shows hemoregulatory effects, intensifies radionuclide efflux from organism. It can be stored under room temperature for several months without the loss of its activity. The data mentioned above let us to conclude that MIGI-K is adaptogenous preparation with wide spectrum of activity.
authors.affiliation: Lomonosov Moscow State University.
authors.forename: E N
authors.initials: EN
authors.lastname: Goncharenko
authors.forename: L I
authors.initials: LI
authors.lastname: Deev
authors.forename: Iu B
authors.initials: IuB
authors.lastname: Kudriashov
authors.forename: I M
authors.initials: IM
authors.lastname: Parkhomenko
mesh_terms: D000818:Animals; D001679:Biogenic Amines / Q000378:metabolism; D006801:Humans; D007107:Immune System / Q000187:drug effects / Q000528:radiation effects; D011210:Power Plants; D011836:Radiation Tolerance; D018788:Radioactive Hazard Release; D011848:Radioactive Pollutants / Q000009:adverse effects*; D011853:Radiobiology; D014455:Ukraine
chemical_list: D001679:Biogenic Amines; D011848:Radioactive Pollutants
vernacular_title: Ispol'zoavnie preparata prirodnogo proiskhozhdeniia dlia oslableniia biologicheskikh éffektov v usloviiakh radioaktivnogo zagriazneniia i v radiobiologicheskom eksperimente.