Interaction of nitrosyl Fe(II) complex of bleomycin with DNA.
ESR spectra of Fe(III)BLM and NO-Fe(II)BLM on highly oriented DNA-fibers indicated that not only the iron binding domain of the BLM but also the orientation of NO bond axis is fixed with respect to the DNA-double helical axis at room temperature.
Chikira
M
M
Department of Applied Chemistry, Chuo University, Tokyo, Japan.
Sakamoto
K
K
Antholine
W E
WE
D000818:Animals; D001482:Base Composition; D001761:Bleomycin / Q000031:analogs & derivatives* / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D004578:Electron Spin Resonance Spectroscopy; D005296:Ferrous Compounds / Q000737:chemistry*; D009690:Nucleic Acid Conformation; D012474:Salmon
D005296:Ferrous Compounds; C023503:iron bleomycin; C113085:nitrosyl iron(II) bleomycin; D001761:Bleomycin; D004247:DNA