title: Histologic findings of transmyocardial laser channels after two hours.
abstract: Histologic examination of the human myocardium has been performed several days, weeks, and months after transmyocardial laser revascularization. We performed microscopic examinations 2 hours postoperatively. In addition to the patent channel (diameter, 1 mm) and a 1-to 2-mm rim of necrosis, a 1- to 3-mm zone of myofibrillary degeneration was found. This additional reversible injury immediately after transmyocardial laser revascularization could explain the higher mortality rate in patients with reduced left ventricular function.
authors.affiliation: Department of Cardiovascular Surgery, University of Freiburg, Germany. lutter@ch11.ukl.uni-freiburg.de
authors.forename: G
authors.initials: G
authors.lastname: Lutter
authors.forename: J
authors.initials: J
authors.lastname: Schwarzkopf
authors.forename: C
authors.initials: C
authors.lastname: Lutz
authors.forename: J
authors.initials: J
authors.lastname: Martin
authors.forename: F
authors.initials: F
authors.lastname: Beyersdorf
mesh_terms: D000368:Aged; D001145:Arrhythmias, Cardiac / Q000209:etiology; D002303:Cardiac Output, Low / Q000209:etiology; D004489:Edema, Cardiac / Q000473:pathology; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D009204:Myocardial Revascularization / Q000379:methods*; D009206:Myocardium / Q000473:pathology*; D009210:Myofibrils / Q000648:ultrastructure; D009336:Necrosis; D015996:Survival Rate; D014654:Vascular Patency; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000601:surgery