title: Artificial death switches: induction of apoptosis by chemically induced caspase multimerization.
authors.affiliation: Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
authors.forename: H
authors.initials: H
authors.lastname: Steller
mesh_terms: D000818:Animals; D017209:Apoptosis / Q000187:drug effects; D020170:Caspase 1; D053148:Caspase 3; D020169:Caspases; D003546:Cysteine Endopeptidases / Q000737:chemistry / Q000378:metabolism*; D019281:Dimerization; D004789:Enzyme Activation; D004792:Enzyme Precursors / Q000737:chemistry / Q000378:metabolism*; D015316:Genetic Therapy / Q000379:methods; D011487:Protein Conformation; D013329:Structure-Activity Relationship
chemical_list: D004792:Enzyme Precursors; D053148:Caspase 3; D020169:Caspases; D003546:Cysteine Endopeptidases; D020170:Caspase 1