title: Two methods of administration of propofol for dental sedation.
abstract: Propofol was used for intravenous sedation in a group of 19 healthy fit young patients undergoing third molar extractions. We compared two ways of giving the drug, patient-controlled and operator-controlled, in a crossover trial. There were no differences between the two methods. The psychomotor functions returned to normal by 60 min, there was a high incidence of partial or complete amnesia and both methods were acceptable to 18/19 patients. There were only minimal changes in the respiratory function, and oxygen saturation remained normal. The only problem noted was mild pain on injection in 4 patients.
authors.affiliation: Department of Anaesthesia and Intensive Care, Dunedin School of Medicine, New Zealand.
authors.forename: M
authors.initials: M
authors.lastname: Zacharias
authors.forename: J
authors.initials: J
authors.lastname: Bridgman
authors.forename: R
authors.initials: R
authors.lastname: Parkinson
mesh_terms: D000293:Adolescent; D000328:Adult; D016058:Analgesia, Patient-Controlled; D000766:Anesthesia, Dental; D018686:Anesthetics, Intravenous / Q000008:administration & dosage*; D016292:Procedural Sedation / Q000379:methods*; D018592:Cross-Over Studies; D005260:Female; D006801:Humans; D015994:Incidence; D007275:Injections, Intravenous / Q000009:adverse effects; D008297:Male; D008568:Memory / Q000187:drug effects; D008964:Molar, Third / Q000601:surgery; D010100:Oxygen / Q000097:blood; D010146:Pain / Q000209:etiology; D017060:Patient Satisfaction; D015742:Propofol / Q000008:administration & dosage*; D011597:Psychomotor Performance / Q000187:drug effects; D012119:Respiration / Q000187:drug effects; D013997:Time Factors; D014081:Tooth Extraction
chemical_list: D018686:Anesthetics, Intravenous; D010100:Oxygen; D015742:Propofol