title: In-vitro antibacterial effects of extracts of Nigerian tooth-cleaning sticks on periodontopathic bacteria.
abstract: Aqueous extracts from 8 plants used for tooth-cleaning in Nigeria were tested for their ability to inhibit the growth of five periodontopathic bacteria, Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, Eikenella corrodens and Campylobacter rectus. Extracts of all the plants except that of Massularia acuminata exhibited varying growth inhibitory potentials on the microorganisms. Extract of Terminalia glaucescens showed the widest spectrum of activity, inhibiting the growth of all the tested bacteria except P. gingivalis. These findings corroborate other studies that the plants possess antiplaque properties and suggest that they may be useful tools in preventive dentistry in poor developing countries. However, the bioavailability of the active ingredients of the plants and their long term effects in vivo need to be investigated.
authors.affiliation: Department of Children's Dentistry, Eastman Dental Institute, London.
authors.forename: E O
authors.initials: EO
authors.lastname: Sote
authors.forename: M
authors.initials: M
authors.lastname: Wilson
mesh_terms: D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D003742:Dental Devices, Home Care; D006801:Humans; D066298:In Vitro Techniques; D008826:Microbial Sensitivity Tests; D009549:Nigeria; D009910:Oral Hygiene / Q000295:instrumentation; D010519:Periodontium / Q000382:microbiology*; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal
chemical_list: D010936:Plant Extracts