Semen-like urethral discharge during the use of mazindol.
Two case reports are described of male patients experiencing a semen-like urethral discharge during micturition, suspected to be induced by mazindol. Mazindol has an indirect sympathomimetic action and is known to cause urogenital side effects such as urinary retention and testicular pain. It is suggested that seminal discharge may be added to this list.
van Puijenbroek
E P
EP
Netherlands Pharmacovigilance Foundation Lareb, MH 's-Hertogenbosch, The Netherlands.
Meyboom
R H
RH
D000328:Adult; D001067:Appetite Depressants / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008454:Mazindol / Q000009:adverse effects*; D009765:Obesity / Q000188:drug therapy*; D012661:Semen; D014521:Urethra; D014522:Urethral Diseases / Q000139:chemically induced*; D014554:Urination
D001067:Appetite Depressants; D008454:Mazindol