[Blood pressure and diastolic function in the elderly].
To evaluate the relation between blood pressure and diastolic function in the elderly, 28 apparently healthy volunteers underwent blood pressure measurements, echocardiographic examinations, and radionuclide angiography acquired in list mode. Casual blood pressure did not correlate with diastolic indices measured either by echocardiography or by a radionuclide method, except for peak filling rate during atrial contraction assessed by radionuclide angiography (r = 0.39, p < 0.05). Ambulatory blood pressure monitoring revealed significant correlations between peak filling rate during atrial contraction assessed by radionuclide angiography and blood pressure measured over 24 hours, while awake and during sleep. The time to peak filling rate and the velocity of early diastolic filling were found to correlate with blood pressure, but the best correlation was between blood pressure during sleep and peak filling rate during atrial contraction (r = 0.53, p < 0.005). These results show a direct relation between blood pressure and diastolic function in the elderly, which is stronger during sleep than during wakefulness.
Odawara
H
H
Department of Medicine and Geriatrics, Kochi Medical School.
Chikamori
T
T
Yabe
T
T
Seo
H
H
Kawamoto
A
A
Ozawa
T
T
Doi
Y
Y
D000368:Aged / Q000502:physiology*; D001794:Blood Pressure / Q000502:physiology*; D003971:Diastole / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged