Effects of non steroidal anti-inflammatory drugs and sulfonamides on hepatic cytochrome P4502C activity in vitro in goats and cattle.
Zweers-Zeilmaker
W M
WM
Faculty of Veterinary Medicine, Department of Veterinary Pharmacology, Pharmacy and Toxicology, Utrecht University, The Netherlands.
Horbach
G J
GJ
Witkamp
R F
RF
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D002417:Cattle; D065607:Cytochrome P-450 Enzyme Inhibitors; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D005260:Female; D006041:Goats; D006900:Hydroxylation; D066298:In Vitro Techniques; D007527:Isoenzymes / Q000037:antagonists & inhibitors*; D008099:Liver / Q000187:drug effects* / Q000201:enzymology; D013449:Sulfonamides / Q000494:pharmacology*; D014044:Tolbutamide / Q000378:metabolism
D000894:Anti-Inflammatory Agents, Non-Steroidal; D065607:Cytochrome P-450 Enzyme Inhibitors; D004791:Enzyme Inhibitors; D007527:Isoenzymes; D013449:Sulfonamides; D014044:Tolbutamide