[Retinal involvement in drepanocytosis in Togo. Correlation between age, genotype and retinopathy].
OBJECTIVE
To evaluate different retinal complications, study correlation with age and links with genotypic forms in Togolese sickle cell patients.


METHODS
Patients were recruited between 1994 and 1996 at the hospital, genotypic diagnosis by electrophoresis, systematic angiofluorography were performed and laser photocoagulation of retinal neovascularisation if needed.


RESULTS
A total number of 190 patients were recruited, 84 (44.21%) had retinopathy, while 106 (55.79%) were normal. The SC form was most affected with 50 patients (26.3%), followed by the SS group in 11.05% (21 patients), and AS trait, 2.65% (5 patients). Patients most affected by proliferative retinopathy were aged 35-44 years (n = 30; 15%), 25-34 years in 23.8% and 15-24 years in 20.6%.


CONCLUSIONS
Young Togolese sickle cell patients aged 35 to 44 year-old and the SC forms appear to have a relative high risk of proliferative retinopathy in this study.
Balo
K P
KP
Service d'Ophtalmologie du CHU Tokoin, Lomé, Togo.
Fany
A
A
Mihluedo
H
H
Djagnikpo
P A
PA
Koffi-Gue
K B
KB
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000755:Anemia, Sickle Cell / Q000150:complications* / Q000235:genetics; D002648:Child; D002675:Child, Preschool; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D012164:Retinal Diseases / Q000209:etiology*; D015861:Retinal Neovascularization / Q000209:etiology; D012307:Risk Factors; D014037:Togo
Atteinte rétinienne au cours de la drépanocytose au Togo. Corrélation entre âge, génotype et rétinopathie.