Portal vein reconstruction with conventional polytetrafluoroethylene grafts: an experimental study in dogs.
The purpose of this study was to examine the short- and long-term performance of conventional polytetrafluoroethylene (PTFE) grafts for portal vein reconstruction. The grafts were placed as a portal vein replacement in 11 mongrel dogs. At 1 month and 6 months, the grafts were then retrieved and examined for patency, while also undergoing a pathological analysis. During the observation period (at 55 days), one dog died of an unknown cause with a patent graft. The patency rates of the other 10 grafts were 83% (5/6) at 1 month and 100% (4/4) at 6 months. However, the neointima formation was incomplete even 6 months after implantation. In conclusion, although conventional PTFE grafts may be used as a synthetic alternative to autogenous vein grafts, every effort should be made to use autogenous vein grafts before considering conventional PTFE grafts.
Nishibe
T
T
Second Department of Surgery, Hokkaido University School of Medicine, Sapporo, Japan.
Manase
H
H
Miyazaki
K
K
Ohkashiwa
H
H
Satoh
Y
Y
Watanabe
S
S
Takahashi
T
T
Katoh
H
H
Okuda
Y
Y
Tanabe
T
T
D000818:Animals; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods; D004285:Dogs; D011138:Polytetrafluoroethylene; D011169:Portal Vein / Q000601:surgery*; D011183:Postoperative Complications; D019651:Plastic Surgery Procedures / Q000379:methods*; D016896:Treatment Outcome
D011138:Polytetrafluoroethylene