title: Smoking and dietary risk factors for cervical cancer at different age group in Japan.
abstract: The importance of the major risk and protective factors for cervical cancer in women by age group was evaluated with the use of data from the Hospital-based Epidemiologic Research Program at Aichi Cancer Center (HERPACC), Japan. This study included 416 cervical cancer cases and 20,985 referents confirmed as free of cancer. Cases and referents were divided into three age groups: the younger, middle and older age groups (30-44, 45-54 and 55-69 years old, respectively). Logistic model was applied separately to the three groups to estimate odds ratios (ORs) of smoking, beverage and dietary habits with adjustment for marital and reproductive factors. The elevated OR of current smokers was observed consistently in all age groups, while alcohol intake did not show any increased ORs. Dietary control for health lowered ORs for all three age groups, and the effect appeared to be more pronounced among the older age group (OR = 0.49, 95% confidence interval: 0.30-0.80). Higher frequency intake of green-yellow vegetables consistently afforded lower ORs among all three age groups. This risk increment of smoking and risk reduction by dietary control were consistent in all age groups. These findings suggested practicable prevention strategy for the cervical cancer by modifying general life style.
authors.affiliation: Division of Epidemiology, Aichi Cancer Center Research Institute, Nagoya, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Hirose
authors.forename: N
authors.initials: N
authors.lastname: Hamajima
authors.forename: T
authors.initials: T
authors.lastname: Takezaki
authors.forename: T
authors.initials: T
authors.lastname: Kuroishi
authors.forename: K
authors.initials: K
authors.lastname: Kuzuya
authors.forename: S
authors.initials: S
authors.lastname: Sasaki
authors.forename: S
authors.initials: S
authors.lastname: Tokudome
authors.forename: K
authors.initials: K
authors.lastname: Tajima
mesh_terms: D000069:Acculturation; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D016001:Confidence Intervals; D005247:Feeding Behavior / Q000208:ethnology; D005260:Female; D019456:Health Transition; D006801:Humans; D007564:Japan / Q000453:epidemiology; D016015:Logistic Models; D008875:Middle Aged; D016017:Odds Ratio; D012907:Smoking / Q000453:epidemiology*; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology*