title: [D-dimer in different stages of pregnancy toxemia. A pilot study].
abstract: We assayed D-Dimer levels in the different stages of preeclampsia. This test appears to be the most reliable for the probability of abnormal status in patients with disseminated intravascular coagulation. Data were analyzed by dividing all cases in four groups: a.-Healthy non pregnan women (10 cases) 550 ng/ml mean levels. B.-Normal pregnant women (8 cases) 875 ng/ml mean levels. C.-Mild and severe preeclamptic patients (8 cases) 1625 ng/ml mean levels, and D.-Eclampsia and HELLP patients (6 cases) 3000 ng/ml. This results were statistical significant at level p < 0.05. It is believed that pregnancy is associated with "hypercoagulability" that it is enhance in toxemia cases. It is necessary to perform more studies with quantitative elisa techniques of D-Dimer, more cases and other markers of dic and endothelial cell injury.
authors.affiliation: Grupo de Estudio de Toxemia Rio Blanco, Ver. Hospital Regional de Rio Blanco S.S.A.
authors.forename: L
authors.initials: L
authors.lastname: Verduzco Rodríguez
authors.forename: E
authors.initials: E
authors.lastname: González Puebla
authors.forename: F
authors.initials: F
authors.lastname: Manffrini Madrid
authors.forename: B
authors.initials: B
authors.lastname: López Ariza
mesh_terms: D000293:Adolescent; D000328:Adult; D001034:Apgar Score; D004211:Disseminated Intravascular Coagulation / Q000175:diagnosis*; D004461:Eclampsia / Q000097:blood* / Q000175:diagnosis; D005260:Female; D017359:HELLP Syndrome / Q000097:blood / Q000175:diagnosis; D006801:Humans; D007231:Infant, Newborn; D010865:Pilot Projects; D011225:Pre-Eclampsia / Q000097:blood / Q000175:diagnosis; D011247:Pregnancy; D018000:Receptors, Peptide / Q000032:analysis*
chemical_list: D018000:Receptors, Peptide; C048650:fibrin-fibrinogen degradation products receptor
vernacular_title: Dímero-D en las diferentes etapas de la toxemia del embarazo. Estudio piloto.