title: Substance use disorders among inpatients with bipolar disorder and major depressive disorder in a general hospital.
abstract: The prevalence and type of substance abuse and dependence were determined for 49 patients with mood disorders on a general hospital psychiatric unit. A standardized diagnostic interview was conducted with a high value of inter-rater reliability. This study found that 18.4% of mood disorder inpatients met the diagnostic criteria for psychoactive substance use disorders by DSM-III-R. Sedatives-hypnotics-anxiolytics was the most common substance use disorder (10.2%), followed by alcohol (6.1%). Patients with major depression had a higher rate of comorbidity with substance use disorders than did the bipolar disorder patients (p = 0.011). The prevalence of sedatives-hypnotics-anxiolytics use disorder among major depression patients was 35.7%, which was higher than that among bipolar disorder patients (0%). Male patients had a significantly higher percentage of substance use disorders than did female patients (p = 0.054). Seventy-seven percent of the patients with a dual diagnosis of mood and substance use disorder were not diagnosed as having substance use disorders by psychiatrists in charge.
authors.affiliation: Department of Psychiatry, Yu-Li Veterans Hospital, Hua-Lien, Taiwan, R.O.C.
authors.forename: C C
authors.initials: CC
authors.lastname: Lin
authors.forename: Y M
authors.initials: YM
authors.lastname: Bai
authors.forename: P G
authors.initials: PG
authors.lastname: Hu
authors.forename: H S
authors.initials: HS
authors.lastname: Yeh
mesh_terms: D000293:Adolescent; D000328:Adult; D001714:Bipolar Disorder / Q000453:epidemiology*; D016009:Chi-Square Distribution; D015897:Comorbidity; D003866:Depressive Disorder / Q000453:epidemiology*; D017831:Diagnosis, Dual (Psychiatry) / Q000706:statistics & numerical data; D003951:Diagnostic Errors / Q000706:statistics & numerical data; D005260:Female; D006787:Hospitals, Veterans / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D011567:Psychiatric Department, Hospital / Q000706:statistics & numerical data; D019966:Substance-Related Disorders / Q000453:epidemiology*; D013624:Taiwan / Q000453:epidemiology