Emerging targets for the development of novel antifungal therapeutics.
Invasive mycoses have become important causes of morbidity and mortality in immunocompromised patients. New approaches for antifungal therapy are required to meet the challenges imposed by these life-threatening infections. Such approaches are being developed through identification of novel biochemical and molecular targets of pathogenic fungi.
Groll
A H
AH
Immunocompromised Host Section, National Cancer Institute, NIH, Bethesda, MD, USA.
De Lucca
A J
AJ
Walsh
T J
TJ
D000935:Antifungal Agents / Q000737:chemistry* / Q000494:pharmacology*; D002462:Cell Membrane / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism; D002473:Cell Wall / Q000737:chemistry / Q000187:drug effects; D004271:DNA, Fungal / Q000378:metabolism; D005656:Fungal Proteins / Q000096:biosynthesis; D010445:Peptide Elongation Factors / Q000096:biosynthesis; D015398:Signal Transduction
D000935:Antifungal Agents; D004271:DNA, Fungal; D005656:Fungal Proteins; D010445:Peptide Elongation Factors