The cell biology of liver fibrogenesis - an imbalance of proliferation, growth arrest and apoptosis of myofibroblasts.
Fibrosis following liver damage and factors influencing this process are discussed with special reference to hepatic stellate cells and their transformation to myo- fibroblasts.
Gressner
A M
AM
Institut für Klinische Chemie und Pathobiochemie - Zentrallaboratorium, RWTH Universitätsklinikum, Pauwelsstrasse 30, D-52057 Aachen, Germany. gressner@rwth-aachen.de
D017209:Apoptosis / Q000502:physiology*; D002455:Cell Division / Q000502:physiology; D005347:Fibroblasts / Q000473:pathology; D006801:Humans; D008103:Liver Cirrhosis / Q000473:pathology*