title: [Immunohistochemical insulin evidence at the injection site].
abstract: Under suspicion on an injection of high doses of insulin with suicidal or homicidal intention, the local detection of a vital injection of insulin is necessary for the critical examination. The submitted immunohistochemical method shows, that: the insulin-specific positive immunoreaction of the subcutaneous fatty tissue is assigned to an injection of insulin, although a missing staining does not exclude a premortal application of insulin, a widened immunopositive intercellular space between the subcutaneous lipocytes as expression of a local edema points to the intravitality of the injection of insulin.
authors.affiliation: Institut für Gerichtliche Medizin, Universität Tübingen.
authors.forename: F
authors.initials: F
authors.lastname: Wehner
authors.forename: H D
authors.initials: HD
authors.lastname: Wehner
authors.forename: M C
authors.initials: MC
authors.lastname: Schieffer
mesh_terms: D000273:Adipose Tissue / Q000737:chemistry*; D000328:Adult; D062787:Drug Overdose; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007273:Injections, Intramuscular; D007328:Insulin / Q000008:administration & dosage / Q000032:analysis*; D016602:Needlestick Injuries / Q000473:pathology*; D012867:Skin / Q000737:chemistry / Q000293:injuries* / Q000473:pathology; D013405:Suicide
chemical_list: D007328:Insulin
vernacular_title: Immunhistochemischer Insulinnachweis an der Injektionsstelle.