title: Primary squamous cell carcinoma of accessory parotid gland duct epithelium: report of a case.
abstract: A rare case of primary squamous cell carcinoma surrounding Stensen's duct in a 75-year-old man is presented. The tumor was a relatively well-defined, hard, subcutaneous mass, measuring 18 x 14 x 9 mm and situated in the right cheek. Microscopic examination of an excisional biopsy specimen revealed tumor cells showing squamous differentiation, a papillary growth pattern, and ductal structures with comedo necrosis. Immunohistochemical studies showed positive reactivity for KL-1 (cytokeratin, monoclonal), epithelial membrane antigen, and carcinoembryonic antigen in some tumor cells. The origin of the tumor was thought to be the accessory parotid gland duct epithelium.
authors.affiliation: Department of Dentistry and Oral Surgery, Hyogo College of Medicine, Nishinomiya, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Sakurai
authors.forename: M
authors.initials: M
authors.lastname: Urade
authors.forename: H
authors.initials: H
authors.lastname: Kishimoto
authors.forename: Y
authors.initials: Y
authors.lastname: Takahashi
authors.forename: S
authors.initials: S
authors.lastname: Hozumi
authors.forename: T
authors.initials: T
authors.lastname: Yanagisawa
mesh_terms: D000368:Aged; D002272:Carcinoembryonic Antigen / Q000032:analysis; D002294:Carcinoma, Squamous Cell / Q000473:pathology*; D002454:Cell Differentiation; D002466:Cell Nucleolus / Q000648:ultrastructure; D002467:Cell Nucleus / Q000648:ultrastructure; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D003593:Cytoplasm / Q000648:ultrastructure; D004848:Epithelium / Q000473:pathology; D006801:Humans; D007633:Keratins / Q000032:analysis; D008297:Male; D018396:Mucin-1 / Q000032:analysis; D009336:Necrosis; D010306:Parotid Gland / Q000473:pathology; D010307:Parotid Neoplasms / Q000473:pathology*; D018987:Salivary Ducts / Q000473:pathology*
chemical_list: D002272:Carcinoembryonic Antigen; D018396:Mucin-1; D007633:Keratins