Postoperative Rhizopus scleritis in a diabetic man.
A 50-year-old diabetic man developed necrotizing scleritis with adjacent keratitis 4 weeks after uncomplicated cataract extraction and intraocular lens implantation through a scleral tunnel incision. Cultures of the necrotic sclera grew Rizopus species. Severe destruction of the globe ensued despite topical, subconjunctival, and intravenous amphotericin B, in combination with hyperbaric oxygen therapy. Histopathological examination of the enucleated globe was consistent with Rhizopus infection. One year later, the patient was well without signs of recurrence.
Locher
D H
DH
Molecular Pathogenesis of Eye Infection Research Center, Dean A. McGee Eye Institute, Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Adesina
A
A
Wolf
T C
TC
Imes
C B
CB
Chodosh
J
J
D000935:Antifungal Agents / Q000627:therapeutic use; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D015353:Eye Enucleation; D015821:Eye Infections, Fungal / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D006801:Humans; D007634:Keratitis / Q000382:microbiology / Q000473:pathology / Q000628:therapy; D019654:Lens Implantation, Intraocular / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009091:Mucormycosis / Q000209:etiology* / Q000473:pathology / Q000628:therapy; D018918:Phacoemulsification / Q000009:adverse effects; D011183:Postoperative Complications / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D012233:Rhizopus / Q000302:isolation & purification*; D012590:Sclera / Q000382:microbiology / Q000473:pathology; D015423:Scleritis / Q000382:microbiology* / Q000473:pathology / Q000628:therapy
D000935:Antifungal Agents