Compatibility of ketamine and morphine injections.
The compatibility of ketamine and morphine mixture was studied. In addition, pH adjustment to minimise local tissue irritation led to no change in stability of the mixture up to pH 5.9. It appears that ketamine and morphine mixtures are stable over a 24 h period.
Lau
M H
MH
Department of Pharmaceutics, Victorian College of Pharmacy, Monash University, Parkville, Australia.
Hackman
C
C
Morgan
D J
DJ
D004338:Drug Combinations; D004347:Drug Interactions; D004355:Drug Stability; D005240:Feasibility Studies; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007267:Injections; D007649:Ketamine / Q000737:chemistry / Q000494:pharmacology* / Q000528:radiation effects; D008027:Light; D009020:Morphine / Q000737:chemistry / Q000494:pharmacology* / Q000528:radiation effects; D017693:Sodium Bicarbonate / Q000494:pharmacology; D013997:Time Factors
D004338:Drug Combinations; D007649:Ketamine; D009020:Morphine; D017693:Sodium Bicarbonate