Autopsy study of patients dying of bleeding diathesis.
Ten thousand & thirty seven autopsies performed from the year 1982 to 1992 were studied retrospectively, to find out the number of deaths due to bleeding diathesis. Eighty-seven (0.87%) patients died due to bleeding diathesis, out of which haemolytic uraemic syndrome (HUS) was seen in 9 cases (10.34%), disseminated intravascular coagulation (DIC) in 67 cases (77.01%) & 11 cases were grouped as miscellaneous. Martius scarlet blue stain was carried out to demonstrate fibrin & depending on the number of thrombi in the glomerulus & blood vessels, the lesions were graded as mild, moderate or severe. Kidney was the most common organ involved in all groups of bleeding diathesis. In DIC kidney & lung involvement was almost equal.
Bhatia
S
S
Department of Pathology, L.T.M.M.C. & L.T.M.G. Hospital, Sion, Bombay.
Ranadive
N
N
Manek
R
R
Deodhar
K
K
D001344:Autopsy; D004211:Disseminated Intravascular Coagulation / Q000150:complications / Q000473:pathology*; D005260:Female; D005337:Fibrin / Q000032:analysis; D006463:Hemolytic-Uremic Syndrome / Q000150:complications / Q000473:pathology*; D006474:Hemorrhagic Disorders / Q000209:etiology*; D006801:Humans; D007668:Kidney / Q000473:pathology; D008168:Lung / Q000473:pathology; D008297:Male; D009336:Necrosis; D012189:Retrospective Studies; D013194:Staining and Labeling; D013927:Thrombosis / Q000473:pathology
D005337:Fibrin