[Dobutamine technetium-99m-MIBI spect in evaluating the effects of coronary interventional management].
OBJECTIVE
To evaluate the effects of coronary interventional management by dobutamine 99mTc-MIBI single photon emission computed tomography (Dobu-ECT).


METHODS
Dobu-ECT was performed in pre- and post-interventional management of 32 patients. Dobutamine was administered intravenously at incremental rates from 5 to 40 micrograms x kg-1.min-1 at 3-minute intervals. At the highest infusion rate, 20 mCi 99mTc-MIBI was injected intravenously, and tomographic imaging was performed after one hour. Rest imagings were taken after 24 hours with a second dose of 99mTc-MIBI.


RESULTS
In 32 patients accepting interventional treatment, within 3-6 months follow-up, the results of Dobu-ECT showed a total effectiveness rate of treatment was 68.1%. 27 patients of whose Dobu-ECT showed significant reversible defects before procedure, the effectiveness rate was 77.8% (21/26), 6 still had reversible ischemia within the follow-up period, and restenoses of 5 patients were confirmed by angiography. We also compared the effect of percutaneous transluminal coronary angioplasty (PTCA) with intracoronary stenting using Dobu-ECT. The results showed that intracoronary stenting was more beneficial than PTCA (81.3% vs 43.8%, P < 0.05)


CONCLUSIONS
Dobu-ECT can be used to evaluate the effect of interventional management and detect restenosis after procedure.
Chen
B
B
Department of Cardiology, People's Hospital, Beijing Medical University.
Xu
C
C
Wang
W
W
D000328:Adult; D000368:Aged; D015906:Angioplasty, Balloon, Coronary; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000628:therapy; D003331:Coronary Vessels / Q000601:surgery; D004280:Dobutamine; D005069:Evaluation Studies as Topic; D005260:Female; D005500:Follow-Up Studies; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019275:Radiopharmaceuticals; D015607:Stents; D017256:Technetium Tc 99m Sestamibi; D015899:Tomography, Emission-Computed, Single-Photon
D019275:Radiopharmaceuticals; D004280:Dobutamine; D017256:Technetium Tc 99m Sestamibi