title: Significance probability mapping in 45 patients with lacuna infarct.
abstract: OBJECTIVE
  To find out the implications of significant probability mapping (SPM) in patients with lacuna infarct.
  
  
  METHODS
  Quantitative electroencephalograms (QEEGs) of 45 patients with lacuna infarcts verified by computerized tomography (CT) were compared with mean power of different frequency bands of the healthy control group by Z transform.
  
  
  RESULTS
  Thirty patients with one focus of lacuna infarct and 15 patients with multiple foci were verified by CT scan. Thirty patients had focus, and the focal abnormality was found by SPM in 22 cases, but only 5 cases by EEGs (P < 0.05). In multiple lacuna infarcts, focal abnormalities were discovered on SPM in 5 cases. Both general and focal abnormalities in the predominant findings were the increased power of slow frequency band. In 13 cases the focal abnormalities were basically in correspondence with the localization verified by CT scan.
  
  
  CONCLUSIONS
  SPM could be helpful in discovering the remote dysfunction of cortex. The sensitivity of SPM was better than the electroencephalogram (EEG) and brain electrical activity mapping (BEAM).
authors.affiliation: Department of Neurology, First Teaching Hospital, Beijing Medical University, China.
authors.forename: W
authors.initials: W
authors.lastname: Wang
authors.forename: X
authors.initials: X
authors.lastname: Wu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001931:Brain Mapping / Q000379:methods*; D002540:Cerebral Cortex / Q000503:physiopathology*; D002544:Cerebral Infarction / Q000145:classification / Q000503:physiopathology*; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity