title: Management and outcome of borderline ovarian tumors incidentally discovered at or after laparoscopy.
abstract: BACKGROUND
  To evaluate in a series of patients with borderline ovarian tumors the clinical findings and the outcome after laparoscopic management.
  
  
  METHODS
  Retrospective study of 25 patients with borderline ovarian tumors first treated by laparoscopic approach.
  
  
  RESULTS
  Thirteen patients had mucinous tumors and 12 had serous tumors. Twenty-one patients had ultrasound examination which detected 24 ovarian cysts including multilocular cysts in 50% of cases and unilocular sonolucent cysts in 25% of cases. The serum CA 125 and CA 199 levels were elevated in 30.7% and 23% respectively. Among the 25 patients first treated by laparoscopic approach, 24 had stage I disease: six of them had cystectomy, seven unilateral salpingo-oophorectomy, two bilateral salpingo-oophorectomy and two laparoscopic hysterectomy with bilateral salpingo-oophorectomy. Seven patients had laparoconversion for presumption of ovarian cancer (5) and failure of laparoscopic procedure (2). One patient with stage III disease had laparoscopic biopsies and subsequent laparotomy. Among the 25 patients, 15 had conservative treatment and 10 had radical treatment. Three recurrences occurred after cystectomy. The mean follow-up was 41 months. Twenty-three patients were alive without evidence of disease, one died of intercurrent disease and one patient was lost to follow-up.
  
  
  CONCLUSIONS
  Our data suggest that the laparoscopic approach to borderline ovarian tumors is possible in early stage disease but associated with a high risk of recurrence after cystectomy.
authors.affiliation: Service de Gynécologie, Hôpital Bichat-Claude Bernard, Paris, France.
authors.forename: E
authors.initials: E
authors.lastname: Darai
authors.forename: J
authors.initials: J
authors.lastname: Teboul
authors.forename: A
authors.initials: A
authors.lastname: Fauconnier
authors.forename: J Y
authors.initials: JY
authors.lastname: Scoazec
authors.forename: J L
authors.initials: JL
authors.lastname: Benifla
authors.forename: P
authors.initials: P
authors.lastname: Madelenat
mesh_terms: D000328:Adult; D000368:Aged; D018394:CA-125 Antigen / Q000097:blood; D018395:CA-19-9 Antigen / Q000097:blood; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008875:Middle Aged; D009367:Neoplasm Staging; D010048:Ovarian Cysts / Q000000981:diagnostic imaging / Q000628:therapy; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging* / Q000276:immunology / Q000517:prevention & control / Q000628:therapy*; D012008:Recurrence; D012189:Retrospective Studies; D016896:Treatment Outcome; D014463:Ultrasonography
chemical_list: D018394:CA-125 Antigen; D018395:CA-19-9 Antigen