title: [Systemic amyloidosis presenting as cholestatic jaundice].
abstract: We present a case of a 68 year old man with general deterioration and recent onset of jaundice that was admitted for clinical evaluation. Previous records were: treated bone tuberculosis, hypertrophic myocardiopathy and ischemic cardiopathy. Physical examination showed liver enlargement without evidence of chronic liver disease. Laboratory studies and other explorations such as abdominal ultrasound, CAT and ERCP did not leed to an objective diagnosis. Therefore, a liver biopsy was performed, showing liver amyloidosis AA type with amyloid deposits in portal spaces. The patient died three months later. The rarity of this clinical presentation is discussed and its poor prognosis outlined. Some peculiarities of liver deposits are reviewed.
authors.affiliation: Sección de Digestivo y Servicio de Anatomía Patológica. Hospital de León. León.
authors.forename: F
authors.initials: F
authors.lastname: Jorquera Plaza
authors.forename: M J
authors.initials: MJ
authors.lastname: Fernández Gundín
authors.forename: J
authors.initials: J
authors.lastname: Espinel Díez
authors.forename: F
authors.initials: F
authors.lastname: Muñoz Nnez
authors.forename: A
authors.initials: A
authors.lastname: Herrera Abián
authors.forename: E
authors.initials: E
authors.lastname: García Lagarto
authors.forename: J L
authors.initials: JL
authors.lastname: Olcoz Goñi
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007565:Jaundice / Q000209:etiology*; D008107:Liver Diseases / Q000175:diagnosis* / Q000473:pathology; D008297:Male
vernacular_title: Ictericia colestásica como forma de presentación de una amiloidosis sistémica.