[The cytological characteristics of a radioresistant variant of the L929 line].
The dose-effect dependence in the dose interval 5-20 Gy the LD50 for L929 cell culture has been investigated. It is 11.8 Gy. After successive irradiation with 12 Gy LD50 of surviving cell has grown to 14 and 16 Gy. The acquisition of radioresistance is accompanied with the increase of cell polymorphism, quantity of intercellular contacts and multikaryon structure formation.
Zinchenko
V A
VA
D000818:Animals; D002461:Cell Line, Transformed / Q000166:cytology / Q000528:radiation effects*; D002470:Cell Survival / Q000528:radiation effects; D004307:Dose-Response Relationship, Radiation; D005347:Fibroblasts / Q000166:cytology / Q000528:radiation effects; D007928:Lethal Dose 50; D051379:Mice; D011836:Radiation Tolerance / Q000528:radiation effects*; D014407:Tumor Cells, Cultured / Q000166:cytology / Q000528:radiation effects
Tsitologicheskaia kharakteristika radiorezistentnogo varianta shtamma L929.