Detection of 2'-deoxyoxanosine by capillary electrophoresis.
We have investigated capillary electrophoresis separation of oxanine (Oxa), a base moiety of 2'-deoxyoxanosine (Figure 1), from various bases. Oxa was not well separated from the others by micelle electrokinetic chromatography which is a general method for separating of the bases. On the other hand, capillary zone electrophoresis showed much improved separation when used pH 12 where the six-membered ring of Oxa is opened.
Suzuki
T
T
Institute of Advanced Energy, Kyoto University, Uji, Japan.
Yamada
M
M
Furukawa
H
H
Kanaori
K
K
Tajima
K
K
Makino
K
K
D000900:Anti-Bacterial Agents / Q000302:isolation & purification; D004249:DNA Damage; D003853:Deoxyribonucleosides / Q000737:chemistry / Q000302:isolation & purification; D019075:Electrophoresis, Capillary / Q000379:methods
D000900:Anti-Bacterial Agents; D003853:Deoxyribonucleosides; C042917:2'-deoxyoxanosine