[The features of color pattern electroretinogram in early primary open-angle glaucoma].
OBJECTIVE
To observe the features of the changes of color pattern electroretinogram (CP-ERG) in early primary open-angle glaucoma (POAG).


METHODS
The detection and analyses of CP-ERGs in 29 patients (48 eyes) with POAG, 10 patients (16 eyes) with ocular hypertension and 33 age-matched normal volunteers (48 eyes) were made.


RESULTS
The changes of CP-ERG in early POAG included reduction of amplitudes of P1 and N2 waves, prolongation of the peak times of red/black N2 and blue/black P1 waves. Part of the patients with ocular hypertension had the amplitude of N2 wave reduced. Five factors including the amplitude of blue/black N2 wave, the amplitudes of red/black P1 and N2 waves, the peak time of red/black N2 wave and the white/black P1 to N2 wave amplitude ratio from CP-ERG which are significantly correlated to the diagnosis of early POAG were selected by the multiple factor stepwise discriminatory analysis, and the stepwise discriminatory function was set up.


CONCLUSIONS
CP-ERG is a useful method in detecting the retinal functions in early POAG, and is helpful to its early diagnosis.
Yang
H
H
Ophthalmology Department, Second Affiliated Hospital, Hunan Medical University, Changsha.
Jiang
Y
Y
Wu
Z
Z
D000328:Adult; D004596:Electroretinography; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000175:diagnosis*; D012160:Retina / Q000503:physiopathology*