Persistence of antibodies to Mycoplasma agalactiae in vaccinated sheep.
We report the results of a study on the persistence of antibodies to Mycoplasma agalactiae in two groups of sheep inoculated with inactivated vaccines: a vaccine in aluminium hydroxide adjuvant and a vaccine in mineral oil adjuvant. Antibody titers were evaluated monthly for a period of 11 months, using an ELISA test prepared with Mycoplasma agalactiae membrane antigen. The antibody titers of the group inoculated with the mineral oil vaccine were significantly higher than those of the group inoculated with the aluminium vaccine and they remained at high levels for up to 11 months. The antibody titers of the group inoculated with the aluminium vaccine 3 months after the vaccination decreased to the values observed before the vaccine inoculation.
Buonavoglia
D
D
Istituto di Malattie Infettive e Parassitarie degli animali Facoltà di Medicina Veterinaria, Università degli Studi, Bari.
Fasanella
A
A
Sagazio
P
P
Tempesta
M
M
Iovane
G
G
Buonavoglia
C
C
D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D007114:Immunization / Q000662:veterinary; D009174:Mycoplasma / Q000276:immunology*; D012756:Sheep; D015164:Vaccines, Inactivated / Q000276:immunology*
D000907:Antibodies, Bacterial; D015164:Vaccines, Inactivated