title: Synthesis and evaluation of the CNS activity of new 4-alkoxyphenylimidazolidin-2-ones.
abstract: Various 4-alkoxyphenylimidazolidin-2-ones were prepared from benzaldehydes via a Curtius rearrangement and were evaluated for their anticonvulsant activities.
authors.affiliation: Centre d'Etudes et de Recherche sur le Médicament de Normandie, Laboratoire de Pharmacochimie, Caen, France.
authors.forename: J
authors.initials: J
authors.lastname: Guillon
authors.forename: V
authors.initials: V
authors.lastname: Lelong
authors.forename: O
authors.initials: O
authors.lastname: Renault
authors.forename: M
authors.initials: M
authors.lastname: Boulouard
authors.forename: P
authors.initials: P
authors.lastname: Dallemagne
authors.forename: S
authors.initials: S
authors.lastname: Rault
authors.forename: M
authors.initials: M
authors.lastname: Robba
mesh_terms: D000818:Animals; D000927:Anticonvulsants / Q000138:chemical synthesis* / Q000494:pharmacology; D001522:Behavior, Animal / Q000187:drug effects; D002490:Central Nervous System / Q000187:drug effects*; D005260:Female; D006993:Hypnotics and Sedatives / Q000138:chemical synthesis* / Q000494:pharmacology; D007093:Imidazoles / Q000138:chemical synthesis* / Q000494:pharmacology; D007928:Lethal Dose 50; D051379:Mice; D009043:Motor Activity / Q000187:drug effects; D009126:Muscle Relaxation / Q000187:drug effects; D018482:Muscle, Skeletal / Q000187:drug effects; D012890:Sleep / Q000187:drug effects; D013329:Structure-Activity Relationship
chemical_list: D000927:Anticonvulsants; D006993:Hypnotics and Sedatives; D007093:Imidazoles