title: [Efficacy and safety of timoptic depot in hypotensive therapy of glaucoma].
abstract: The efficacy of timoptic depot is assessed in 20 patients with open-angle glaucoma, previously treated with 0.25 and 0.5% timolol. Instillations of 0.25 and 0.5% timoptic depot for 4 weeks did not appreciably change the intraocular pressure, no local or general side effects were noted. Hence, timoptic depot is a more convenient drug for glaucoma patients, remaining effective even after long use.
authors.forename: V P
authors.initials: VP
authors.lastname: Erichev
authors.forename: L V
authors.initials: LV
authors.lastname: Iakubova
mesh_terms: D000287:Administration, Topical; D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D000368:Aged; D001794:Blood Pressure / Q000187:drug effects; D003692:Delayed-Action Preparations; D004305:Dose-Response Relationship, Drug; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000188:drug therapy*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D009883:Ophthalmic Solutions; D012449:Safety; D013999:Timolol / Q000008:administration & dosage / Q000627:therapeutic use*; D014065:Tonometry, Ocular; D016896:Treatment Outcome
chemical_list: D000319:Adrenergic beta-Antagonists; D003692:Delayed-Action Preparations; D009883:Ophthalmic Solutions; D013999:Timolol
vernacular_title: Effektivnost' i bezopasnost' ispol'zovaniia timoptic-depo v gipotenzivnoĭ terapii glaukomy.