[Clinical evaluation of the use of propoleum in Peyronie's disease].
OBJECTIVE
To analyze the clinical efficacy of propoleum in Peyronie's disease.


METHODS
A controlled, double-blind clinical trial based on a previous pilot study was conducted in 34 patients with Peyronie's disease treated with propoleum (Cuban Academy of Sciences patent no. 21875). The study was performed at the Freyre de Andrade Hospital in Habana. The clinical course and ultrasound features of the fibrous plaque were evaluated during a period of 6 months.


RESULTS
A marked improvement was observed for penile curvature and pain in the treated group. Furthermore, plaque consistency and size was reduced five-fold after treatment and two-fold at ultrasound evaluation. No clinical or ultrasound changes were observed in the control group.


CONCLUSIONS
Our results demonstrate the efficacy of propoleum in Peyronie's disease.
Lemourt Oliva
M
M
Servicio de Urología, Radiología, Hospital de Andrade, Centro Habana, Cuba.
Filgueiras López
E
E
Rodríguez Barroso
A
A
González Oramas
E
E
Bordonado
R
R
D000328:Adult; D000368:Aged; D001688:Biological Products / Q000627:therapeutic use*; D004311:Double-Blind Method; D006801:Humans; D008297:Male; D008875:Middle Aged; D010411:Penile Induration / Q000628:therapy*; D011446:Prospective Studies
D001688:Biological Products
Evaluación clínica del uso del propóleo en la enfermedad de Peyronie.