[Survival and quality of life of patients with testicular cancer].
Cisplatin has revolutionized the prognosis of testicular cancers. Stage I non-seminomatous germ cell tumours can be cured in 98% of cases; adjuvant therapy, chemotherapy or lymph node dissection, is recommended in high-risk tumours, while surveillance is indicated in tumours with a low risk of recurrence. Good prognosis metastatic non-seminomatous germ cell tumours are cured in almost 80% of cases at the cost of well tolerated chemotherapy, 3 BEP or 4 EP. The morbidity of lymph node dissection has been markedly decreased by means of various techniques of preservation of all or part of the sympathetic and lumbar contingent. Resection of residual masses after chemotherapy for metastatic non-seminomatous germ cell tumours is still recommended in the majority of cases. Stage I seminomatous germ cell tumours are cured in 98% of cases by 25 Grays of lumbo-aortic radiotherapy. Screening for carcinoma in situ in the contralateral testis to the primary tumour is controversial, but is recommended in the case of lowering of a maldesended testis after the age of puberty. Future paternity is a major concern in tumours of young adults, most of which are cured.
Lugagne Delpon
P M
PM
Service d'Urologie, Hôpital Foch, Suresnes.
Petit
M
M
Houlgatte
A
A
Droz
J P
JP
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005047:Etoposide / Q000008:administration & dosage; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D011379:Prognosis; D011788:Quality of Life; D016019:Survival Analysis; D013736:Testicular Neoplasms / Q000401:mortality / Q000523:psychology* / Q000601:surgery*
D001761:Bleomycin; D005047:Etoposide; D002945:Cisplatin
Survie et qualité de vie des cancers du testicule.