title: Telangiectatic osteosarcoma of the skull base.
abstract: We present a patient with a distinctive lesion of the skull base, which, at imaging, showed expansile destruction of the sphenoid bone, hemorrhage with fluid-fluid levels, and contrast enhancement of a solid portion. These features ordinarily suggest either giant cell tumor or aneurysmal bone cyst; however, pathologic examination confirmed instead a rare variant of osteosarcoma of the telangiectatic type. Although imaging findings can indicate any of these possibilities, biopsy is an essential step in arriving at the diagnosis.
authors.affiliation: Department of Radiology, Boston University Medical Center, MA 02118, USA.
authors.forename: R E
authors.initials: RE
authors.lastname: Whitehead
authors.forename: E R
authors.initials: ER
authors.lastname: Melhem
authors.forename: J
authors.initials: J
authors.lastname: Kasznica
authors.forename: S
authors.initials: S
authors.lastname: Eustace
mesh_terms: D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012516:Osteosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D019292:Skull Base Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D013100:Sphenoid Bone / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed