Analysis of guanine oxidation product via electron transfer in 5'-d(TTGGTA)-3'.
The photoirradiation of 5'-TTGGTA-3' in the presence of riboflavin with or without complementary oligomer 5'-ATACCAAA-3' was investigated by HPLC analysis. It was found that 2-aminoimidazol-4-one (Iz) containing hexamers, 5'-TTIzGTA-3' and 5'-TTGIzTA-3', were the major products.
Kino
K
K
Faculty of Engineering, Kyoto University, Japan.
Sugiyama
H
H
Saito
I
I
D001483:Base Sequence; D002851:Chromatography, High Pressure Liquid; D004583:Electrons; D006147:Guanine / Q000031:analogs & derivatives* / Q000737:chemistry* / Q000528:radiation effects; D009838:Oligodeoxyribonucleotides / Q000737:chemistry* / Q000528:radiation effects; D010084:Oxidation-Reduction; D010777:Photochemistry; D012256:Riboflavin
D009838:Oligodeoxyribonucleotides; D006147:Guanine; D012256:Riboflavin