title: [Critical review of renal transplantation data from the Piedmontese Regional Dialysis and Transplantation Registry].
abstract: On 31/12/1995 a total of 1,128 Piedmontese uremic patients had undergone kidney transplantation, with 65% of operations performed by the Regional Reference Centre and 35% by extra-regional centres. Waiting time for dialysis was less than 5 years in over half of the patients most of whom were aged between 40 and 60 years old. In overall terms, the patient survival rate was 94%, 87%, 75% at 24, 60, 120 months respectively, with a statistically significant improvement when the curve was evaluated in the patient-pool treated with cyclosporine (84% versus 87% at 7 years). Organ survival was 76% at 21 years and 42% at 10 years, and results were again improved by the use of cyclosporine. Pathologies affecting the transplanted organ represent the main cause of morbidity; drop-out during dialysis is caused above all by immunological diseases. Infectious pathologies were responsible for the majority of deaths in this population.
authors.affiliation: Unità Operativa di Nefrologia e Dialisi, Ospedale Castelli, Verbania.
authors.forename: A
authors.initials: A
authors.lastname: Baroni
authors.forename: M
authors.initials: M
authors.lastname: Pozzato
authors.forename: M
authors.initials: M
authors.lastname: Fabiano
authors.forename: A
authors.initials: A
authors.lastname: Serra
authors.forename: A
authors.initials: A
authors.lastname: Vallero
authors.forename: S
authors.initials: S
authors.lastname: Cusinato
authors.forename: M
authors.initials: M
authors.lastname: Salomone
mesh_terms: D000293:Adolescent; D000328:Adult; D002318:Cardiovascular Diseases / Q000401:mortality; D002423:Cause of Death; D002648:Child; D002675:Child, Preschool; D016572:Cyclosporine / Q000627:therapeutic use; D004363:Drug Utilization / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007223:Infant; D007239:Infections / Q000401:mortality; D007558:Italy / Q000453:epidemiology; D007676:Kidney Failure, Chronic / Q000401:mortality / Q000601:surgery*; D016030:Kidney Transplantation / Q000401:mortality / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000401:mortality; D012042:Registries / Q000706:statistics & numerical data*; D012086:Reoperation; D016019:Survival Analysis
chemical_list: D007166:Immunosuppressive Agents; D016572:Cyclosporine
vernacular_title: Revisione critica dei dati riguardanti il trapianto renale nel Registro Regionale Piemontese di Dialisi e Trapianto (RPDT).