Alpha-fetoprotein serum concentration in different stages of liver cirrhosis.
Serum alpha-fetoprotein (AFP) concentration was measured in 41 patients with different stages of liver cirrhosis demonstrated through scored Child-Pugh classification. Mean value was elevated up to 65.9 21.9 U/l, butstatistically significant difference in comparison with control group was observed only in patients classified as Child-Pugh C. AFP concentration revealed significant positive correlation with score values. Dynamics of AFP during one-year follow up demonstrated three-fold and statistically significant increase of its concentration, that was accompanied by elevation of mean score values.
Wiercińska-Drapało
A
A
Department of Infectious Diseases, Medical Academy of Białystok.
Flisiak
R
R
Prokopowicz
D
D
D001201:Ascites; D001663:Bilirubin / Q000097:blood; D001706:Biopsy; D018450:Disease Progression; D005260:Female; D005500:Follow-Up Studies; D006501:Hepatic Encephalopathy / Q000145:classification; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood* / Q000145:classification / Q000473:pathology; D017093:Liver Failure / Q000097:blood / Q000145:classification; D008297:Male; D011516:Prothrombin / Q000032:analysis; D012709:Serum Albumin / Q000032:analysis; D000509:alpha-Fetoproteins / Q000032:analysis*
D012709:Serum Albumin; D000509:alpha-Fetoproteins; D011516:Prothrombin; D001663:Bilirubin