[Analytical confirmation of error in false positive amphetamine immunoassays and results].
Numerous urine samples were found to be positive when using a new amphetamine immunoassay (AxSYM). Confirmation analysis was carried out in a second laboratory at "reasonable prices" using a simple TLC-method with non specific ninhydrine detection and resulted in many "positive" confirmation findings. The GC/MS analysis clearly indicated the absence of amphetamine derivatives regularly encountered in forensic toxicology. The false-positive immunochemical findings may probably be caused by endogenous substances.
Schütz
H
H
Institut für Rechtsmedizin, Universität Giessen.
Erdmann
F
F
Magiera
E S
ES
Weiler
G
G
D000661:Amphetamine / Q000652:urine*; D005189:False Positive Reactions; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007118:Immunoassay / Q000592:standards
D000661:Amphetamine
Fehlerhafte Bestätigungsanalytik bei falsch-positiven Amphetamin-Immunoassays und ihre Auswirkungen.