title: Thermography and nailfold capillaroscopy as noninvasive measures of circulation in children with Raynaud's phenomenon.
abstract: OBJECTIVE
  To determine in a pilot study the feasibility of noninvasive techniques of (a) measurement of rewarming response after a standard cold challenge test (using thermographic imaging) and (b) measurement of nailfold capillary dimensions using video capillaroscopy, in the assessment of children presenting with Raynaud's phenomenon (RP).
  
  
  METHODS
  Ten children with RP and 10 age matched healthy controls were studied. No child had definite evidence of underlying connective tissue disease.
  
  
  RESULTS
  Children with RP had abnormal rewarming curves. The gradient of the rewarming curve was significantly lower in children with RP (median 1.5 vs 5.0 degrees C/min in controls; p = 0.015), and there was a trend for the lag time (the interval between the end of the cold challenge and the onset of rewarming) to be increased in children with RP (median 4.7 vs 0.5 min in controls; p = 0.08). Capillary dimensions were measured in 7 of the children with RP, and were similar to those of healthy controls.
  
  
  CONCLUSIONS
  Thermography and nailfold capillaroscopy are feasible in children and should be further evaluated.
authors.affiliation: University of Manchester Rheumatic Diseases Centre, Hope Hospital, Salford, UK.
authors.forename: S
authors.initials: S
authors.lastname: Jayanetti
authors.forename: C P
authors.initials: CP
authors.lastname: Smith
authors.forename: T
authors.initials: T
authors.lastname: Moore
authors.forename: M I
authors.initials: MI
authors.lastname: Jayson
authors.forename: A L
authors.initials: AL
authors.lastname: Herrick
mesh_terms: D000293:Adolescent; D002196:Capillaries; D002648:Child; D002675:Child, Preschool; D003080:Cold Temperature; D005240:Feasibility Studies; D005260:Female; D005385:Fingers / Q000098:blood supply*; D006801:Humans; D008297:Male; D010865:Pilot Projects; D011928:Raynaud Disease / Q000503:physiopathology*; D012039:Regional Blood Flow; D013817:Thermography