Cytokines in dementia of the Alzheimer's type (DAT): relevance to research and treatment.
There is indirect evidence suggesting that some cytokines may be involved in the pathophysiology of dementia of the Alzheimer type (DAT). Measurement of proinflammatory cytokines in the biologic fluids and brain tissues of DAT patients have provided some support for such a role. However, these studies are limited in scope and have included a relatively small number of patients. Future studies are needed to elucidate the role of cytokines in the pathogenesis and treatment of DAT.
Malek-Ahmadi
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Department of Neuropsychiatry School of Medicine Texas Tech University Health Sciences Center, Lubbock 79430, USA.
D000368:Aged; D000544:Alzheimer Disease / Q000378:metabolism* / Q000628:therapy*; D001923:Brain Chemistry / Q000502:physiology; D016207:Cytokines / Q000378:metabolism*; D006801:Humans
D016207:Cytokines