[Lung cancer surgery in a patient with idiopathic thrombocytopenic purpura (ITP)].
A 59-year-old woman was hospitalized due to an abnormal chest X-ray film. Chest X-ray examination revealed an irregular opacity in the right S6 area. Adenocarcinoma was diagnosed by bronchoscopic exfoliative cytology. Preoperative hematology tests showed a low platelet count and further investigation suggested the presence of idiopathic thrombocytopenic purpura. Preoperative high-dose immunoglobulin therapy (400 mg/kg/day for five days) and platelet transfusion allowed the operation to be performed successfully (resection of the inferior lobe of the right lung and removal of regional lymphnodes). High-dose immunoglobulin therapy is thought to be a very useful method with few adverse effects for the rapid increase of platelet count to prevent massive hemorrhage.
Tsuchishima
S
S
Department of Thoracic and Cardiovascular Surgery, Kanazawa Medical University, Ishikawa, Japan.
Shimizu
T
T
Yuasa
K
K
Ooya
N
N
Nishizawa
H
H
D000230:Adenocarcinoma / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000008:administration & dosage; D008175:Lung Neoplasms / Q000150:complications / Q000601:surgery*; D008875:Middle Aged; D017713:Platelet Transfusion; D011300:Preoperative Care; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications*
D007136:Immunoglobulins