Vitamin E serum levels in Rett syndrome.
In order to study the role of vitamin E in the pathogenesis of Rett syndrome (RS), we analysed vitamin E serum levels in twenty-eight patients affected by this disorder. We found lower vitamin E serum levels in nine cases (32.1%). These results indicated that the oxidative free radical metabolism may be impaired in a significant percentage of Rett syndrome patients suggesting the need for further studies of tissue vitamin E in different brain regions.
Formichi
P
P
Institute of Neurological Sciences, University of Siena, Policlinico Le Scotte, Italy.
Battisti
C
C
Dotti
M T
MT
Hayek
G
G
Zappella
M
M
Federico
A
A
D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002784:Cholesterol / Q000097:blood; D005260:Female; D006801:Humans; D015518:Rett Syndrome / Q000097:blood*; D014810:Vitamin E / Q000097:blood*
D014810:Vitamin E; D002784:Cholesterol