title: [Multifocal electroretinography in acquired macular dysfunction].
abstract: BACKGROUND
  Multifocal electroretinography allows physiological mapping of the central retina. The purpose of this study was to describe the spatial distribution of ERG-activity in patients with impairment of macular function which usually do not exhibit a pathologic Ganzfeld-ERG.
  
  
  METHODS
  6 patients with macular lesions due to uveitis (4), retinitis centralis serosa (1), and contusio bulbi (1) were examined using the multifocal ERG technique.
  
  
  RESULTS
  In normal volunteers the response density of the multifocal ERG decreased with eccentricity according to cone density distribution. In eyes with impaired central vision the foveal and macular responses were markedly diminished while surrounding signals were of normal or moderately decreased amplitudes.
  
  
  CONCLUSIONS
  With the multifocal ERG disturbances of macular function due to oedema and secondary structural changes were detected in the presented cases and the extension of the central lesions was estimated.
authors.affiliation: Abteilung Pathophysiologie des Sehens und Neuro-Ophthalmologie, Universitäts-Augenklinik Tübingen.
authors.forename: U
authors.initials: U
authors.lastname: Kretschmann
authors.forename: T
authors.initials: T
authors.lastname: Schlote
authors.forename: N
authors.initials: N
authors.lastname: Stübiger
authors.forename: K
authors.initials: K
authors.lastname: Gendo
authors.forename: E
authors.initials: E
authors.lastname: Hipp
authors.forename: E
authors.initials: E
authors.lastname: Zrenner
mesh_terms: D000293:Adolescent; D000328:Adult; D003196:Computer Graphics; D003288:Contusions / Q000175:diagnosis / Q000503:physiopathology; D003937:Diagnosis, Differential; D004596:Electroretinography / Q000379:methods*; D005131:Eye Injuries / Q000175:diagnosis / Q000503:physiopathology; D005260:Female; D006801:Humans; D008266:Macula Lutea / Q000503:physiopathology*; D008297:Male; D017949:Retinal Cone Photoreceptor Cells / Q000503:physiopathology; D012164:Retinal Diseases / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D012173:Retinitis / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D012815:Signal Processing, Computer-Assisted; D014605:Uveitis / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology
vernacular_title: Multifokale Elektroretinographie bei erworbenen Makulafunktionsstörungen.