Characterization of the phenotype conferred by two different rpsL alleles coding for streptomycin dependence.
Two streptomycin-dependent strains of E. coli B showing different phenotypes were isolated. They carried different rpsL alleles which conferred two levels of dependence on the drug, and showed a different expression when present in heterozygous conditions with other rpsL alleles, coding for sensitivity or resistance on the drug.
Lagatolla
C
C
Dipartimento di Scienze Biomediche, Università di Trieste, Italy.
Dolzani
L
L
Monti-Bragadin
C
C
D000483:Alleles; D000900:Anti-Bacterial Agents / Q000378:metabolism*; D004352:Drug Resistance, Microbial / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D029968:Escherichia coli Proteins; D005798:Genes, Bacterial / Q000235:genetics*; D008826:Microbial Sensitivity Tests; D010641:Phenotype; D017354:Point Mutation; D000091243:Ribosomal Protein S9; D012269:Ribosomal Proteins / Q000235:genetics; D013307:Streptomycin / Q000378:metabolism*
D000900:Anti-Bacterial Agents; D029968:Escherichia coli Proteins; D000091243:Ribosomal Protein S9; D012269:Ribosomal Proteins; C000717190:RpsI protein, E coli; D013307:Streptomycin