title: [Two cases of tinea capitis with different clinical courses].
abstract: We report cases of two 4-year-old boys with tinea capitis who attend the same daynursery. Clinically, on the first visit both lesions were a superficial type, however we initiated treatment with a dose of 50 mg/day of oral itraconazole. Althougth the lesion of case 2 improved after 11 weeks of treatment, case 1 developed to kerion celsi and required continued treatment for 22 weeks for cure. Microsporum canis was isolated from the hairs of both cases and MIC of itraconazole against both isolates was 1 micro g/ml. We specurate that secondary bacterial infection was responsible for the development to kelion celsi in case 2.
authors.affiliation: Department of Dermatology, Tokyo Women's Medical University Daini Hospital, 2-1-10 Nishiogu, Arakawa-ku, Tokyo, 116-8567, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Ishizaki
authors.forename: H
authors.initials: H
authors.lastname: Ito
authors.forename: H
authors.initials: H
authors.lastname: Hanyaku
authors.forename: T
authors.initials: T
authors.lastname: Harada
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use*; D008297:Male; D012535:Scalp / Q000473:pathology; D014006:Tinea Capitis / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole