A high-resolution microsatellite map of the mouse genome.
The European Collaborative Interspecific Backcross (EUCIB) resource was constructed for the purposes of high-resolution genetic mapping of the mouse genome (). The large Mus spretus/C57BL/6 backcross of 982 progeny has a genetic resolution of 0.3 cM at the 95% confidence level ( approximately 500 kb in the mouse genome). We have used the EUCIB mapping resource to develop a genome-wide high-resolution genetic map incorporating 3368 microsatellites. The microsatellites are distributed among 2302 genetically separated bins with 1.46 markers per bin on average. Average bin separation is 0.61 cM. This high-resolution genetic map will aid the construction of a robust physical map of the mouse genome.
Rhodes
M
M
United Kingdom Human Genome Mapping Project (HGMP) Resource Centre, Hinxton CB10 1RQ, UK.
Straw
R
R
Fernando
S
S
Evans
A
A
Lacey
T
T
Dearlove
A
A
Greystrong
J
J
Walker
J
J
Watson
P
P
Weston
P
P
Kelly
M
M
Taylor
D
D
Gibson
K
K
Mundy
C
C
Bourgade
F
F
Poirier
C
C
Simon
D
D
Brunialti
A L
AL
Montagutelli
X
X
Gu'enet
J L
JL
Haynes
A
A
Brown
S D
SD
D000818:Animals; D002874:Chromosome Mapping / Q000379:methods* / Q000706:statistics & numerical data; D002875:Chromosomes / Q000235:genetics; D003433:Crosses, Genetic; D016208:Databases, Factual; D005819:Genetic Markers / Q000235:genetics; D016678:Genome; D005838:Genotype; D051379:Mice; D008810:Mice, Inbred C57BL / Q000235:genetics*; D018895:Microsatellite Repeats / Q000235:genetics*; D009115:Muridae / Q000235:genetics; D011336:Probability; D011995:Recombination, Genetic
D005819:Genetic Markers