Transcriptional regulation of the human proenkephalin gene by conformational switching: implications for decoy design.
Spiro
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Department of Pharmacology, Mayo Clinic and Foundation, Rochester, MN 55905, USA.
McMurray
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D001483:Base Sequence; D016384:Consensus Sequence; D017362:Cyclic AMP Response Element-Binding Protein / Q000378:metabolism; D004274:DNA, Recombinant / Q000235:genetics; D015195:Drug Design; D004742:Enhancer Elements, Genetic / Q000187:drug effects / Q000235:genetics; D004745:Enkephalins / Q000096:biosynthesis / Q000235:genetics*; D005796:Genes; D006801:Humans; D008969:Molecular Sequence Data; D015394:Molecular Structure; D009690:Nucleic Acid Conformation / Q000187:drug effects*; D016376:Oligonucleotides, Antisense / Q000737:chemistry / Q000494:pharmacology*; D010957:Plasmids / Q000235:genetics; D011485:Protein Binding; D011498:Protein Precursors / Q000096:biosynthesis / Q000235:genetics*; D013329:Structure-Activity Relationship; D013873:Thionucleotides / Q000737:chemistry / Q000494:pharmacology; D014158:Transcription, Genetic / Q000187:drug effects*; D015533:Transcriptional Activation / Q000187:drug effects
D017362:Cyclic AMP Response Element-Binding Protein; D004274:DNA, Recombinant; D004745:Enkephalins; D016376:Oligonucleotides, Antisense; D011498:Protein Precursors; D013873:Thionucleotides; C029992:proenkephalin