Isolation of 1-carboxymethylnicotinic acid from the marine sponge anthosigmella cf. raromicrosclera As a cysteine protease inhibitor1
1-Carboxymethylnicotinic acid (1) has been isolated from a marine sponge Anthosigmella cf. raromicrosclera as a cysteine protease inhibitor. The structure was elucidated by spectral data and chemical synthesis.
Matsunaga
S
Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Kamimura
T
Fusetani
N