[Mathematical model of the mechanical properties of skeletal muscle fibres taking into account compliance of the actin filaments].
A mathematical model describing mechanical transients induced by the step length changes in skeletal muscle fibres is suggested. The model takes into account compliance of actin filaments and the cross-bridge mechanics. Two different approaches were used for modeling of the cross-bridges: the Huxley-Simmons (1971) model and a new nonlinear viscoelasic model. From a comparison of the results of computer simulation with experimental data we conclude that the best fitting is achieved by using a combined model where both Huxley-Simmons mechanism and cross-bridges viscoelastisity are represented.
Shestakov
D A
DA
Institute of Mechanics, Lomonosov Moscow State University, Russia.
Tsaturian
A K
AK
D000199:Actins / Q000502:physiology*; D000818:Animals; D006801:Humans; D008954:Models, Biological; D008962:Models, Theoretical; D009119:Muscle Contraction / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology*
D000199:Actins
Matematicheskaia model' mekhanicheskikh svoĭstv volokon skeletnoĭ my shtsy s uchetom rastiazhimosti aktinovykh niteĭ.