title: Reference cDNA library facilities available from European sources.
abstract: cDNA libraries are the cornerstone of efforts to identify the relatively small regions of genomes that are responsible for biological effects. Gene hunter seeking candidate genes, via a variety of approaches, ultimately focus on the cloning, sequencing, and expression of cDNAs. Assistance is now available to researchers in the form of genome programs, whose initial goals include assembly of a complete collection of expressed sequences derived from the genome of interest. The concept of reference sets of cDNA libraries is that the aims of genome programs are served most effectively by different laboratories working on a common set of high-quality arrayed cDNA libraries, using different experimental approaches, thereby reducing unnecessary duplication of effort, and maximizing the amount of information that one set of resources can provide.
authors.affiliation: UK HGMP Resource Centre, Hinxton, Cambridge, UK. mstarkey@hgmp.mrc.ac.uk
authors.forename: M P
authors.initials: MP
authors.lastname: Starkey
authors.forename: Y
authors.initials: Y
authors.lastname: Umrania
authors.forename: C R
authors.initials: CR
authors.lastname: Mundy
authors.forename: M J
authors.initials: MJ
authors.lastname: Bishop
mesh_terms: D018076:DNA, Complementary; D016208:Databases, Factual; D005060:Europe; D015698:Genomic Library; D016045:Human Genome Project; D006801:Humans; D016247:Information Storage and Retrieval; D012984:Software
chemical_list: D018076:DNA, Complementary