Lafora bodies associated with neurologic signs in a cat.
Lafora bodies (polyglucosan deposits) were identified in the brain of a young adult cat with neurologic signs characterized by intermittent but progressively worsening head and body tremors. The cerebellar cortex was the most severely affected area of brain, and the deposits were identified within Purkinje cell bodies and processes and throughout the neuropil. The association of Lafora bodies with neurologic signs, occurrence of deposits within neuronal perikarya, and distribution primarily within the cerebellar cortex are features distinct from the more commonly recognized situation in which Lafora bodies occur as incidental lesions in cats.
Hall
D G
DG
Department of Pathology, College of Veterinary Medicine, University of Georgia, Athens 30602-7388, USA.
Steffens
W L
WL
Lassiter
L
L
D000818:Animals; D001927:Brain Diseases / Q000175:diagnosis / Q000378:metabolism / Q000662:veterinary*; D002371:Cat Diseases / Q000175:diagnosis* / Q000378:metabolism; D002415:Cats; D002525:Cerebellar Cortex / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D005260:Female; D005936:Glucans / Q000378:metabolism / Q000648:ultrastructure; D002479:Inclusion Bodies / Q000378:metabolism / Q000473:pathology* / Q000648:ultrastructure; D011689:Purkinje Cells / Q000378:metabolism / Q000473:pathology / Q000648:ultrastructure
D005936:Glucans; C083094:polyglucosan