Recurrent acute transverse myelopathy associated with anticardiolipin antibodies.
In three patients with recurrent episodes of acute transverse myelopathy, spinal MR imaging during each episode showed areas of hyperintensity on proton density- and T2-weighted images with inconsistent contrast enhancement. Cranial MR imaging, laboratory screenings, and CSF analysis showed only increased titers of anticardiolipin antibodies. Although a causative role in neurologic conditions has not been established conclusively, an association between these antibodies and acute transverse myelopathy and its recurrences cannot be ignored.
Campi
A
A
Department of Neuroradiology, Scientific Institute H.S. Raffaele, University of Milan, Italy.
Filippi
M
M
Comi
G
G
Scotti
G
G
D000208:Acute Disease; D000328:Adult; D017153:Antibodies, Anticardiolipin / Q000032:analysis*; D016736:Antiphospholipid Syndrome / Q000150:complications / Q000175:diagnosis / Q000276:immunology; D002648:Child; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D012008:Recurrence; D013116:Spinal Cord / Q000473:pathology; D013118:Spinal Cord Diseases / Q000150:complications / Q000276:immunology*
D017153:Antibodies, Anticardiolipin