A model of in vivo dosimetry and quality assurance analysis of total body irradiation in Zagreb.
The aim of the study was to develop a systemic and simple method for determination of midplane dose factors and lung correction factors, suitable for semiconductor 60-Co total body irradiation (TBI) in vivo dosimetry, based on input (entrance) and output (exit) dose readings. A theoretical model of anthropomorphic phantoms of cylindrical ellipsoid shape made it possible to generalize the applicability to any individual case of the real patient's data. Also, the quality assurance analysis of dosimetric results of 230 patients who had undergone TBI during a 10-year period, was performed. The ratio of the mean measured dose values for all locations in all patients and stated dose (12.45 Gy in 3 days, 3 fractions) was 0.998, SD 0.033. The upper limit of the total combined uncertainty of TBI midplane absorbed dose, including all locations and all sources of error, amounted to 9.4%.
Vrtar
M
M
University Department of Oncology and Radiotherapy, University Hospital Centre, Zagreb, Croatia.
Kovacević
N
N
D006801:Humans; D019047:Phantoms, Imaging; D011785:Quality Assurance, Health Care; D011879:Radiotherapy Dosage; D014916:Whole-Body Irradiation / Q000379:methods* / Q000592:standards