title: Underreading of the tuberculin skin test reaction.
abstract: OBJECTIVE
  The tuberculin skin test is the best diagnostic method to detect tuberculous infection. How accurate is interpretation of the test?
  
  
  METHODS
  Observational study.
  
  
  METHODS
  Both general hospital and university hospital.
  
  
  METHODS
  One hundred seven health-care professionals, including 52 practicing pediatricians, 33 pediatric house officers, 10 pediatric academicians, 11 registered nurses, and 1 pediatric nurse practitioner.
  
  
  METHODS
  A tuberculin skin test (Mantoux) was applied to the arm of a known tuberculin converter. As participants entered/left the room, they were guided to the tuberculin converter. At no time did a participant observe readings other than his/her own.
  
  
  RESULTS
  Mantoux tuberculin reaction measuring 15 mm induration was read individually by a group of 52 practicing pediatricians, 33 pediatric house officers, 10 pediatric academicians, 11 registered nurses, and one pediatric nurse practitioner. The median induration recorded by this group of 107 health-care professionals was 10 mm, and 17 (33%) practicing pediatricians read the reaction as <10 mm induration. Using the > or = 15-mm induration indicator to identify a positive reaction, 93% of those in the study (99/107 participants) would have identified our known converter as tuberculin negative.
  
  
  CONCLUSIONS
  This study confirms a general inaccuracy in interpretation of the tuberculin skin test reaction. It raises two questions. (1) Is there a general tendency toward underreading? (2) Does this general tendency to underread tuberculin skin test reactions raise some question as to the American Academy of Pediatrics, American Thoracic Society, and Centers for Disease Control and Prevention move in raising the amount of induration considered tuberculin positive to 15 mm in low-risk individuals?
authors.affiliation: Department of Pediatrics and Biostatistics, Medical College of Virginia, Virginia Commonwealth University, Richmond, USA.
authors.forename: E L
authors.initials: EL
authors.lastname: Kendig
authors.forename: B V
authors.initials: BV
authors.lastname: Kirkpatrick
authors.forename: W H
authors.initials: WH
authors.lastname: Carter
authors.forename: F A
authors.initials: FA
authors.lastname: Hill
authors.forename: K
authors.initials: K
authors.lastname: Caldwell
authors.forename: M
authors.initials: M
authors.lastname: Entwistle
mesh_terms: D000328:Adult; D003951:Diagnostic Errors; D005260:Female; D006801:Humans; D008297:Male; D008505:Medical Staff, Hospital; D009741:Nursing Staff, Hospital; D010372:Pediatrics; D010820:Physicians; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity; D014374:Tuberculin Test / Q000592:standards; D014376:Tuberculosis / Q000175:diagnosis* / Q000453:epidemiology