title: Expression of c-fos, fos B, and egr-1 in the medial preoptic area and bed nucleus of the stria terminalis during maternal behavior in rats.
abstract: The spatial and temporal pattern of expression of the protein products of immediate early genes (IEGs) c-fos, fos B, and egr-1 were mapped in medial preoptic area (MPOA) and ventral bed nucleus of stria terminalis (VBST) during maternal behavior in rats. Immunocytochemical analysis indicated significant increases in the number of cells expressing c-Fos after 2 h of pup exposure, while Fos B levels showed a delayed response, reaching maximal levels after 6 h.
authors.affiliation: Department of Psychology, Boston College, Chestnut Hill, MA 02167, USA. mnuman@cu.uned.es
authors.forename: M
authors.initials: M
authors.lastname: Numan
authors.forename: M J
authors.initials: MJ
authors.lastname: Numan
authors.forename: S R
authors.initials: SR
authors.lastname: Marzella
authors.forename: A
authors.initials: A
authors.lastname: Palumbo
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000502:physiology; D004268:DNA-Binding Proteins / Q000032:analysis / Q000096:biosynthesis*; D051766:Early Growth Response Protein 1; D005260:Female; D017781:Genes, Immediate-Early / Q000502:physiology; D017874:Immediate-Early Proteins; D008425:Maternal Behavior / Q000502:physiology*; D011301:Preoptic Area / Q000737:chemistry / Q000378:metabolism*; D016760:Proto-Oncogene Proteins c-fos / Q000032:analysis / Q000096:biosynthesis*; D051381:Rats; D011919:Rats, Inbred Strains; D014157:Transcription Factors / Q000032:analysis / Q000096:biosynthesis*; D016335:Zinc Fingers / Q000502:physiology
chemical_list: D004268:DNA-Binding Proteins; D051766:Early Growth Response Protein 1; C486110:Egr1 protein, rat; D017874:Immediate-Early Proteins; D016760:Proto-Oncogene Proteins c-fos; D014157:Transcription Factors