title: Lack of seroreactivity to Ehrlichia chaffeensis among rodent populations.
abstract: A retrospective serosurvey for antibodies to Ehrlichia chaffeensis was conducted on eight species of wild rodents (Mus musculus, Oryzomys palustris, Peromyscus leucopus, Rattus norvegicus, Reithrodontomys humulis, Sciurus carolinensis, Sciurus niger, and Sigmodon hispidus) from the southeastern United States. Serum samples (n = 281) collected between 1973 and 1993 were evaluated using an indirect fluorescent antibody test. All samples, screened at a dilution of 1:32, were negative for antibodies to E. chaffeensis. Sixty-three percent of the rodents tested were from areas where E. chaffeensis has been confirmed or is strongly suspected to be endemic. These data suggest limited or no involvement of rodents in the epidemiology of E. chaffeensis.
authors.affiliation: Southeastern Cooperative Wildlife Disease Study, College of Veterinary Medicine, University of Georgia, Athens 30602, USA.
authors.forename: J M
authors.initials: JM
authors.lastname: Lockhart
authors.forename: W R
authors.initials: WR
authors.lastname: Davidson
authors.forename: D E
authors.initials: DE
authors.lastname: Stallknecht
authors.forename: J E
authors.initials: JE
authors.lastname: Dawson
mesh_terms: D000818:Animals; D000835:Animals, Wild; D000907:Antibodies, Bacterial / Q000097:blood*; D004197:Disease Reservoirs; D018469:Ehrlichia chaffeensis / Q000276:immunology*; D016873:Ehrlichiosis / Q000453:epidemiology / Q000276:immunology / Q000662:veterinary*; D019084:Fluorescent Antibody Technique, Indirect / Q000662:veterinary; D051379:Mice; D008809:Mice, Inbred C3H; D051381:Rats; D012189:Retrospective Studies; D012376:Rodent Diseases / Q000453:epidemiology* / Q000276:immunology; D012377:Rodentia; D015144:Southeastern United States / Q000453:epidemiology
chemical_list: D000907:Antibodies, Bacterial