title: Ligand-free MHC class I conformation.
abstract: Perhaps the most important structural questions regarding MHC molecules concern what changes occur when the MHC molecule binds peptide. Extensive new biochemical evidence indicates that peptide-empty MHC class I molecules adapt an unstable and partially folded conformation.
authors.forename: T
authors.initials: T
authors.lastname: Hansen
mesh_terms: D000818:Animals; D015395:Histocompatibility Antigens Class I / Q000737:chemistry*; D006801:Humans; D008024:Ligands; D051379:Mice; D008954:Models, Biological; D011487:Protein Conformation
chemical_list: D015395:Histocompatibility Antigens Class I; D008024:Ligands