title: The smoothened gene and hedgehog signal transduction in Drosophila and vertebrate development.
authors.affiliation: Molecular Embryology Laboratory, Imperial Cancer Research Fund, London, United Kingdom.
authors.forename: J
authors.initials: J
authors.lastname: Quirk
authors.forename: M
authors.initials: M
authors.lastname: van den Heuvel
authors.forename: D
authors.initials: D
authors.lastname: Henrique
authors.forename: V
authors.initials: V
authors.lastname: Marigo
authors.forename: T A
authors.initials: TA
authors.lastname: Jones
authors.forename: C
authors.initials: C
authors.lastname: Tabin
authors.forename: P W
authors.initials: PW
authors.lastname: Ingham
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D019521:Body Patterning; D012831:Bombyx / Q000196:embryology; D002642:Chick Embryo; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000196:embryology*; D004625:Embryo, Nonmammalian / Q000502:physiology*; D004627:Embryonic Induction; D017344:Genes, Insect; D053823:Hedgehog Proteins; D006801:Humans; D019476:Insect Proteins / Q000502:physiology*; D008958:Models, Molecular; D008969:Molecular Sequence Data; D016296:Mutagenesis; D011487:Protein Conformation; D011956:Receptors, Cell Surface / Q000096:biosynthesis / Q000235:genetics / Q000502:physiology*; D043562:Receptors, G-Protein-Coupled; D011994:Recombinant Proteins / Q000096:biosynthesis; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D015398:Signal Transduction; D000072086:Smoothened Receptor; D014714:Vertebrates / Q000196:embryology*
chemical_list: D029721:Drosophila Proteins; D053823:Hedgehog Proteins; D019476:Insect Proteins; D011956:Receptors, Cell Surface; D043562:Receptors, G-Protein-Coupled; D011994:Recombinant Proteins; C491023:SMO protein, human; D000072086:Smoothened Receptor; C100664:smo protein, Drosophila; C077245:hh protein, Drosophila