Inhibition by 3'-azido-3'-deoxythymidine (AZT) of Trypanosoma cruzi growth in mammalian cells and a possible mechanism of action.
Nakajima-Shimada
J
J
Department of Parasitology, Juntendo University, School of Medicine, Tokyo, Japan.
Aoki
T
T
D000818:Animals; D000981:Antiprotozoal Agents / Q000494:pharmacology*; D015224:Dideoxynucleosides / Q000494:pharmacology*; D006678:HIV / Q000201:enzymology; D006367:HeLa Cells; D006801:Humans; D008322:Mammals; D012194:RNA-Directed DNA Polymerase / Q000378:metabolism; D018894:Reverse Transcriptase Inhibitors / Q000494:pharmacology*; D014349:Trypanosoma cruzi / Q000187:drug effects / Q000201:enzymology / Q000254:growth & development*; D015215:Zidovudine / Q000494:pharmacology*
D000981:Antiprotozoal Agents; D015224:Dideoxynucleosides; D018894:Reverse Transcriptase Inhibitors; D015215:Zidovudine; D012194:RNA-Directed DNA Polymerase