[Determination of plasma D-dimer in patients with pregnancy induced hypertension].
OBJECTIVE
To investigate the changes and the clinical significance of plasma D-dimer in normal pregnant women and patients with pregnancy induced hypertension (PIH).


METHODS
Using ELISA method, we measured the level of plasma D-dimer in 160 cases, including 106 normal pregnant women and 25 patients with mild and moderate PIH, 18 patients with preeclampsia and 11 patients with eclampsia.


RESULTS
The value (2.27 +/- 0.92 mg/L) of plasma D-dimer in mild and moderate PIH patients was markedly higher than that of normal third trimester pregnant women (1.45 +/- 0.38 mg/L, P < 0.01). The value (3.09 +/- 1.65 mg/L) of plasma D-dimer in preeclampsia patients was markedly higher than that of mild and moderate PIH patients (P < 0.01). The value (5.62 +/- 1.34 mg/L) of plasma D-dimer in eclampsia patients was markedly higher than that of preeclampsia patients.


CONCLUSIONS
Determination of plasma D-dimer level in second and third trimester pregnant women was of great significance in diagnosing early PIH and predicting the prognosis of PIH.
Zhou
H
H
First Hospital of San Ming, Fu Jian.
Chen
R
R
Liu
X
X
D000328:Adult; D000933:Antifibrinolytic Agents / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism*; D006801:Humans; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D011379:Prognosis
D000933:Antifibrinolytic Agents; D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D