title: Multicentric malignant transformation of multiple exostoses.
abstract: We treated a patient with large multiple chondrosarcomas derived from multiple cartilaginous exostoses. One sarcoma originated in the left pubic bone and the other sarcoma in the posterior aspect of the greater trochanter of the left femur. Thirty months after hindquarter amputation, the patient is alive without relapse. This is the first report of a patient with synchronous multiple malignant transformation of multiple cartilaginous exostoses.
authors.affiliation: Department of Orthopaedics, Westfälische Wilhelms-University, Münster, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Ozaki
authors.forename: A
authors.initials: A
authors.lastname: Hillmann
authors.forename: S
authors.initials: S
authors.lastname: Blasius
authors.forename: T
authors.initials: T
authors.lastname: Link
authors.forename: W
authors.initials: W
authors.lastname: Winkelmann
mesh_terms: D000368:Aged; D001859:Bone Neoplasms / Q000175:diagnosis* / Q000473:pathology; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D005097:Exostoses, Multiple Hereditary / Q000175:diagnosis* / Q000473:pathology; D005266:Femoral Neoplasms / Q000175:diagnosis / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis* / Q000473:pathology; D015831:Osteochondroma / Q000175:diagnosis* / Q000473:pathology; D011230:Precancerous Conditions / Q000175:diagnosis* / Q000473:pathology; D011630:Pubic Bone / Q000473:pathology; D014057:Tomography, X-Ray Computed