[Parvovirus B19 as infectious agent in infants].
OBJECTIVE
Since its casual discovery and implication as a human pathogen that provokes transitory aplastic crises and infectious erythema, the B19 parvovirus has been related to a wide spectrum of diseases. To better understand this clinical diversity, we reviewed the cases of a serology positive infants admitted to the hospital.


METHODS
From January 1992 to June 1995, all clinical charts were reviewed and we obtained 15 patients that had positive IgM antibodies by immunoenzyme assay.


RESULTS
The mean age was 12.2 months. No sex differences were seen. The incidence was higher in winter months. Over 50% of the patients belong to the last year studied. Clinical findings included 5 cases of arthritis (one juvenile rheumatoid arthritis, one polyarticular syndrome and 3 nonspecific forms), hematology disturbances in 5 cases (1 case of erythrophagocytosis, 1 of thrombocytopenic purpura, 2 of anemia and 1 chronic neutropenia), 3 cases of febrile syndrome, 1 liver dysfunction, and 1 neuromyelitis. Complementary exams were not significant and follow-up in all infants was satisfactory.


CONCLUSIONS
The B19 parvovirus, a poorly understood virus, is related to many clinical situations where is true significance remains unknown.
Angulo Barreras
M P
MP
Departamento de Pediatría, Hospital de Cruces, Baracaldo.
Fernández López
A
A
Pérez de Saracho Taramona
M
M
Labayru Etxeberria
M
M
Pocheville Guruzeta
I
I
Gutiérrez Villamayor
C
C
Sojo Aguirre
A
A
D017677:Age Distribution; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000276:immunology; D007223:Infant; D008297:Male; D010322:Parvoviridae Infections / Q000175:diagnosis* / Q000276:immunology / Q000821:virology*; D016732:Parvovirus B19, Human / Q000302:isolation & purification*; D012189:Retrospective Studies
D007075:Immunoglobulin M
El parvovirus B19 como agente infeccioso en el lactante.