Sonographic evaluation of the placental cord insertion site.
OBJECTIVE
Velamentous and marginal umbilical cords are uncommon abnormalities of placental cord insertion that can entail significant fetal risk. We undertook this investigation to assess the ability of prenatal sonography to reveal abnormal insertions of the umbilical cord into the placenta.


METHODS
Forty-six patients had both prenatal sonographic evaluation of the placental cord insertion site and postnatal pathologic examination. Distance from the insertion site to the nearest placental edge was categorized by sonography and pathology as normal if greater than 1 cm and abnormal if less than or equal to 1 cm. Sonographic and pathologic findings were compared.


RESULTS
Thirty-eight singleton and eight twin pregnancies, for a total of 54 cord insertions, were studied. Of the 43 sonographically normal insertions, 38 had normal pathologic findings, and the remaining five insertions had abnormal pathologic findings (all marginal cord insertions). All 11 insertions that showed abnormality on sonography were abnormal on pathologic examination (seven marginal and four velamentous insertions). Sonography was able to reveal a difference between the two types of abnormal insertions in only a single patient, in whom the cord insertion changed from marginal to velamentous during a 7-week interval. Sonography had an overall sensitivity of 69% (11/16), a specificity of 100% (38/38), and an accuracy of 91% (49/54) for revealing abnormal placental cord insertion sites.


CONCLUSIONS
Targeted sonographic examination of the placental site of umbilical cord insertion will reveal abnormal placental cord insertions, although distinguishing the specific type of abnormal insertion may require the use of color Doppler imaging.
Di Salvo
D N
DN
Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Benson
C B
CB
Laing
F C
FC
Brown
D L
DL
Frates
M C
MC
Doubilet
P M
PM
D002823:Chorion / Q000000981:diagnostic imaging; D005260:Female; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D010920:Placenta / Q000002:abnormalities / Q000000981:diagnostic imaging* / Q000473:pathology; D011247:Pregnancy; D011272:Pregnancy, Multiple; D011446:Prospective Studies; D012680:Sensitivity and Specificity; D014427:Twins; D018615:Ultrasonography, Doppler, Color; D016216:Ultrasonography, Prenatal; D014470:Umbilical Cord / Q000002:abnormalities / Q000000981:diagnostic imaging* / Q000473:pathology