title: Microbiology and antibiotic treatment of head and neck abscesses in children.
abstract: The clinical data, microbiological results and antibiotic treatment of 65 children who have required incision and drainage of suppurative head and neck abscesses was retrospectively investigated with the aim of developing a more effective clinical protocol of treatment, improving speed of resolution and rationalizing the need for surgical intervention. A positive culture grew in 78% of children and of these 45% were Staphylococcus aureus, 9% Streptococcus pyogenes, and 8% atypical mycobacteria. Only 3% of the samples grew anaerobes. All isolates of S. aureus were sensitive to Flucloxacillin and all isolates of S. pyogenes were sensitive to penicillin. All anaerobes were Metronidazole sensitive. In 40% of the children there were no localizing symptoms which could guide the treatment, therefore we recommend Flucloxacillin and Metronidazole as the antibiotic regimen of choice in acute suppurative lymphadenitis. The increasing incidence of atypical mycobacterial lymphadenitis is noteworthy.
authors.affiliation: Department of Otolaryngology, Booth Hall Children's Hospital, University of Manchester, UK.
authors.forename: R
authors.initials: R
authors.lastname: Simo
authors.forename: C
authors.initials: C
authors.lastname: Hartley
authors.forename: F
authors.initials: F
authors.lastname: Rapado
authors.forename: A P
authors.initials: AP
authors.lastname: Zarod
authors.forename: D
authors.initials: D
authors.lastname: Sanyal
authors.forename: M P
authors.initials: MP
authors.lastname: Rothera
mesh_terms: D000038:Abscess / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001421:Bacteria, Anaerobic / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D004322:Drainage; D005260:Female; D005436:Floxacillin / Q000627:therapeutic use; D006257:Head / Q000382:microbiology*; D006801:Humans; D015994:Incidence; D007223:Infant; D008199:Lymphadenitis / Q000188:drug therapy / Q000382:microbiology; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D009165:Mycobacterium Infections, Nontuberculous / Q000188:drug therapy / Q000601:surgery; D009333:Neck / Q000382:microbiology*; D010406:Penicillins / Q000627:therapeutic use; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000601:surgery; D013290:Streptococcal Infections / Q000188:drug therapy / Q000601:surgery; D013297:Streptococcus pyogenes; D013492:Suppuration
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins; D008795:Metronidazole; D005436:Floxacillin