title: [Significance of the expression of HLA-DR on keratinocytes in oral lichen planus lesions].
abstract: In this article, the expression of HLA-DR in keratinocytes in lesions of oral lichen planus (OLP) was investigated, using an immunohistochemical technique (PAP method). The results showed: HLA-DR positive keratinocytes were found in all groups of patients, the numbers and expressive degree of HLA-DR were related to types and duration of OLP, there were higher statistically significant differences between different groups and types of OLP (P < 0.01). The authors considered that the expression of HLA-DR in keratinocytes plays an important role in gathering T cells and forming inflammation in OLP lesions.
authors.affiliation: Department of Stomatology 371 Hospital of PLA, Xinxiang.
authors.forename: Z
authors.initials: Z
authors.lastname: Guan
authors.forename: H
authors.initials: H
authors.lastname: Li
mesh_terms: D000328:Adult; D005260:Female; D006684:HLA-DR Antigens / Q000378:metabolism*; D006651:Histocytochemistry; D006801:Humans; D015603:Keratinocytes / Q000276:immunology*; D017676:Lichen Planus, Oral / Q000276:immunology*; D008297:Male; D008875:Middle Aged
chemical_list: D006684:HLA-DR Antigens