[How can we measure a diameter of each entrance of a ion channel recording only channel conductance?].
The channel formed by colicin Ia in planar lipid bilayer was used to develop a method determining a diameter of each channel entrance. The method is based on measuring of a channel filling with nonelectrolytes through cis- and trans-entrance separately. To do this, one need to establish the two things only: the conductance of an ion channel and the conductivity of used solutions. Using the method to predict the internal geometry of a channel lumen is discussed.
Krasil'nikov
O V
OV
Institute of Physiology and Biophysics, Tashkent, Uzbekistan.
Da Cruz
J B
JB
Nogueira
R A
RA
D003087:Colicins / Q000737:chemistry*; D004594:Electrophysiology / Q000379:methods*; D015640:Ion Channel Gating; D007473:Ion Channels / Q000737:chemistry* / Q000502:physiology; D008051:Lipid Bilayers / Q000737:chemistry*
D003087:Colicins; D007473:Ion Channels; D008051:Lipid Bilayers
Kak izmerit' diametr kazhdogo vkhoda u ionnogo kanala, regestriruia tol'ko ego provodimost'?