title: [Primary polycythaemia vera in the elderly].
abstract: We present an 86-years-old woman's case with paralysis in her left hand of abrupt apparition, accompanied by arterial hypertension and dizziness. The investigation revealed erythrocytosis, leukocytosis, thrombocytosis, with normal arterial O2 saturation (O2 SAT), increased of his red cell volume and blood viscosity. The polycythaemia vera (PV) was diagnose and the paralysis disappeared, when 24 hours before a phlebotomy was practiced, and the function was recovered by the hand. We analysed the presents diagnostics criteria of the disease defined by Polycythaemia Vera Study Group (PVSG). The different treatments for PV are discussed; in addition to venesection, conventional treatment include chemotherapy with hydroxyurea and pipobroman, as well as the erythropheresis, -interferon and aspirin. All of the treatments are associated with complications; thrombotic in the case of phlebotomy; malignancies and gastrointestinal bleeding in the case of myelosuppressive treatments and aspirin. We think the optimal treatment for PV is a judicious combination of the available alternatives, depending on the phase of the disease, and the age of the patient.
authors.affiliation: Servicio de Medicina Interna, Hospital Clínico Universitario de Valencia.
authors.forename: F
authors.initials: F
authors.lastname: Gabriel Botella
authors.forename: M
authors.initials: M
authors.lastname: Labiós Gómez
authors.forename: J
authors.initials: J
authors.lastname: Sempere Montés
authors.forename: A
authors.initials: A
authors.lastname: Nicolau Arrufat
authors.forename: M
authors.initials: M
authors.lastname: Martínez Silvestre
authors.forename: A
authors.initials: A
authors.lastname: Vayá Montaña
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D011087:Polycythemia Vera / Q000175:diagnosis*
vernacular_title: La policitemia vera en el anciano.