title: A second primary squamous cell carcinoma arising in a radial forearm flap used for reconstruction of the hypopharynx.
abstract: A 63-year-old man had undergone hypopharyngectomy for hypopharyngeal carcinoma in 1985. A free radial forearm flap was used for reconstruction of the pharynx. Ten years after the surgery, a second primary squamous cell carcinoma occurred in the neopharynx. Persistent exposure to alcohol, saliva and foodstuffs was considered as a possible cause of second primary carcinoma. Long-term follow-up is indicated in patients undergoing reconstruction using cutaneous or musculocutaneous flaps.
authors.affiliation: Department of Otolaryngology, Faculty of Medicine, University of Tokyo, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Sakamoto
authors.forename: K
authors.initials: K
authors.lastname: Nibu
authors.forename: M
authors.initials: M
authors.lastname: Sugasawa
authors.forename: T
authors.initials: T
authors.lastname: Nakatsuka
authors.forename: K
authors.initials: K
authors.lastname: Harii
authors.forename: K
authors.initials: K
authors.lastname: Ichimura
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005542:Forearm / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000473:pathology*; D010610:Pharyngeal Neoplasms / Q000473:pathology / Q000601:surgery*; D013524:Surgical Flaps