title: Workshop studies with monoclonal antibodies identifying a novel porcine differentiation antigen, SWC9.
abstract: Two monoclonal antibodies (mAb) within cluster M4 of the myeloid section of the Second International Swine CD Workshop, C4 (No. 144) and PM18-7 (No. 192), showed reactivity with thymocytes and among cells of myelomonocytic origin with mature macrophages but not with monocytes and granulocytes. Both mAb recognize a protein showing two bands of 205 kDa and 130 kDa under both reducing and non-reducing conditions. Although epitope mapping with these mAb could not be performed, this cluster received the SWC9 designation.
authors.affiliation: Centro de Investigación en Sanidad Animal INIA, Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Dominguez
authors.forename: A
authors.initials: A
authors.lastname: Ezquerra
authors.forename: F
authors.initials: F
authors.lastname: Alonso
authors.forename: R
authors.initials: R
authors.lastname: Bullido
authors.forename: K
authors.initials: K
authors.lastname: McCullough
authors.forename: A
authors.initials: A
authors.lastname: Summerfield
authors.forename: A
authors.initials: A
authors.lastname: Bianchi
authors.forename: R J
authors.initials: RJ
authors.lastname: Zwart
authors.forename: Y B
authors.initials: YB
authors.lastname: Kim
authors.forename: F
authors.initials: F
authors.lastname: Blecha
authors.forename: S
authors.initials: S
authors.lastname: Eicher
authors.forename: M P
authors.initials: MP
authors.lastname: Murtaugh
authors.forename: M
authors.initials: M
authors.lastname: Pampusch
authors.forename: K
authors.initials: K
authors.lastname: Burger
mesh_terms: D000818:Animals; D000911:Antibodies, Monoclonal / Q000378:metabolism*; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis*; D007700:Kinetics; D008264:Macrophages / Q000276:immunology; D016676:Macrophages, Alveolar / Q000276:immunology; D009000:Monocytes / Q000276:immunology; D011233:Precipitin Tests; D013552:Swine / Q000276:immunology*; D013556:Swine, Miniature; D016176:T-Lymphocyte Subsets / Q000276:immunology
chemical_list: D000911:Antibodies, Monoclonal; D015214:Antigens, Differentiation, Myelomonocytic