[An NMDA glutamate receptor subtype].
Glutamate is the main excitatory synaptic transmitter between neurones in the central nervous system. The excitatory effect of glutamate is due to activation of two distinct types of receptor ion channels-AMPA/kainate and NMDA type. This article reviews recent discoveries concerning molecular structure of NMDA receptor channels, its pharmacology and biophysics including excitatory postsynaptic currents mediated by activation of this subtype of glutamate receptor.
Turecek
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R
Fyziologický ústav AV CR, Praha.
Vyklický
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L
D000818:Animals; D006801:Humans; D016194:Receptors, N-Methyl-D-Aspartate / Q000187:drug effects / Q000378:metabolism / Q000502:physiology
D016194:Receptors, N-Methyl-D-Aspartate
NMDA podtyp glutamátového receptoru.