title: [Driving fitness in therapy with antidepressive drugs].
abstract: The driving ability of patients under therapy with antidepressives is seen less restrictive than some years ago. The inhibition of psychomotor performance is of special interest. Some empirical studies point at antidepressives increasing the risk for accidents at least in elderly patients. Different groups of antidepressants apparently show different effects. Tricyclic antidepressants were shown to worsen cognitive and psychomotor performance in some patients while serotonin reuptake inhibitors and some other new antidepressants may cause less behavioral toxicity. Methodological problems in assessing driving ability and some recent findings are discussed.
authors.affiliation: Psychiatrischen Klinik, Universität München.
authors.forename: M
authors.initials: M
authors.lastname: Soyka
authors.forename: S
authors.initials: S
authors.lastname: Dittert
authors.forename: A
authors.initials: A
authors.lastname: Gartenmeier
authors.forename: M
authors.initials: M
authors.lastname: Schäfer
mesh_terms: D000328:Adult; D016907:Adverse Drug Reaction Reporting Systems; D000368:Aged; D000928:Antidepressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001288:Attention / Q000187:drug effects; D001334:Automobile Driving / Q000331:legislation & jurisprudence*; D003071:Cognition / Q000187:drug effects; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011597:Psychomotor Performance / Q000187:drug effects; D011930:Reaction Time / Q000187:drug effects
chemical_list: D000928:Antidepressive Agents
vernacular_title: Fahrtauglichkeit unter Therapie mit Antidepressiva.