Optical recording of responses to frequency-modulated sounds in the auditory cortex.
Using an optical recording method with a voltage-sensitive dye, we recorded activities in the primary auditory cortex (AI) of anesthetized guinea pigs in response to frequency-modulated (FM) sounds and sounds with stepwise changes in frequency (SF). Responses to the FM sound showed a spatiotemporal pattern in which a localized active spot traversed the isofrequency bands in the AI, and they differed from the band-like responses to the SF sound. These results indicate that time-varying sounds are represented as spatiotemporal activation of tonotopic organization in the AI by spectral cues with interactions between frequency bands.
Horikawa
J
J
Department of Neurophysiology, Medical Research Institute, Tokyo Medical and Dental University, Japan.
Nasu
M
M
Taniguchi
I
I
D000161:Acoustic Stimulation; D000818:Animals; D001303:Auditory Cortex / Q000502:physiology*; D004594:Electrophysiology; D005456:Fluorescent Dyes; D006168:Guinea Pigs
D005456:Fluorescent Dyes