title: Expression of an ascidian gene in the tip of the tail of tail-bud-stage embryos.
abstract: The occurrence of tadpole-type larvae is one of the key events used to understand the origin and evolution of chordates, and the tail bud of chordate embryos is thought to be associated with formation of the tip of the tail. Although some transcriptional factor genes including Brachyury are expressed in the tail bud, no structural genes have been reported to be expressed there. We report here that an ascidian gene HrTT-1 is expressed exclusively in the tip of elongating tail of the tail-bud embryo. This gene encodes a possible secreted protein of 415 amino acids with the SCP/TPX family consensus sequences.
authors.affiliation: Department of Zoology, Graduate School of Science, Kyoto University, Kyoto 606-01, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Hotta
authors.forename: H
authors.initials: H
authors.lastname: Takahashi
authors.forename: N
authors.initials: N
authors.lastname: Satoh
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D018076:DNA, Complementary; D004625:Embryo, Nonmammalian / Q000378:metabolism*; D015870:Gene Expression; D017403:In Situ Hybridization; D008565:Membrane Proteins / Q000096:biosynthesis / Q000235:genetics*; D008969:Molecular Sequence Data; D017386:Sequence Homology, Amino Acid; D013623:Tail / Q000196:embryology; D014561:Urochordata / Q000235:genetics*
chemical_list: D018076:DNA, Complementary; C112929:HrTT-1 protein, Halocynthia roretzi; D008565:Membrane Proteins