title: Role of deoxycytidine kinase (dCK), thymidine kinase 2 (TK2), and deoxycytidine deaminase (dCDA) in the antitumor activity of gemcitabine (dFdC).
authors.affiliation: Department of Med. Oncology, University Hospital VU, Amsterdam, The Netherlands.
authors.forename: J R
authors.initials: JR
authors.lastname: Kroep
authors.forename: C J
authors.initials: CJ
authors.lastname: van Moorsel
authors.forename: G
authors.initials: G
authors.lastname: Veerman
authors.forename: D A
authors.initials: DA
authors.lastname: Voorn
authors.forename: R M
authors.initials: RM
authors.lastname: Schultz
authors.forename: J F
authors.initials: JF
authors.lastname: Worzalla
authors.forename: L R
authors.initials: LR
authors.lastname: Tanzer
authors.forename: R L
authors.initials: RL
authors.lastname: Merriman
authors.forename: H M
authors.initials: HM
authors.lastname: Pinedo
authors.forename: G J
authors.initials: GJ
authors.lastname: Peters
mesh_terms: D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000627:therapeutic use*; D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy / Q000201:enzymology*; D003564:Cytidine Deaminase; D003841:Deoxycytidine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003842:Deoxycytidine Kinase / Q000378:metabolism*; D019008:Drug Resistance, Neoplasm; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000201:enzymology*; D051379:Mice; D009700:Nucleoside Deaminases / Q000378:metabolism*; D010190:Pancreatic Neoplasms / Q000188:drug therapy / Q000201:enzymology*; D013937:Thymidine Kinase / Q000378:metabolism*; D014183:Transplantation, Heterologous; D000093542:Gemcitabine
chemical_list: D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; C105339:thymidine kinase 2; D013937:Thymidine Kinase; D003842:Deoxycytidine Kinase; D009700:Nucleoside Deaminases; D003564:Cytidine Deaminase; C011530:deoxycytidine deaminase; D000093542:Gemcitabine