[Resistance of Haemophilus sp. to antibiotics].
The present study was undertaken to determine the in vitro drug resistance of Haemophilus influenzae (68 isolates) and H. parainfluenzae (17 isolates). The tests susceptibility to Ampicillin, Amoxicilin/Clavulanic Acid, Cefaclor, Cefuroxime, Cotrimoxazole, Aztreonam, Ceftriaxone, Tetracycline, Ciprofloxacin, Rifampicin and Chloramphenicol were performed with a standard disk-diffusion method. The NCCLS methodology and susceptibility interpretative criteria were applied as described by the disk manufacturer. Beta-lactamase production was detected with nitrocefin impregnated disk (Cefinase, BBL Microbiology System). Resistance in nosocomially acquired Haemophilus isolates to several antibiotics was observed. Of the Haemophilus isolates 28.2% were Ampicillin in resistant, all were susceptible to the combination of Amoxicillin/Clavulanic acid. The Ampicillin-resistant strains were beta-lactamase producers. We observed the high resistance (70.1%) to Tetracycline and (28.2%) to SXT (Cotrimoxazole). All isolates of Haemophilus were susceptible to Ciprofloxacin. The low resistance percentages to Rifampin (1.2%), Aztreonam (3.5%) and Chloramphenicol (3.5%) was observed.
Janicka
G
G
Katedry i Zakładu Mikrobiologii Państwowego Szpitala Klinicznego Akademii Medycznej w Bydgoszczy.
Gospodarek
E
E
Mikucka
A
A
Białek
M
M
Wojak
I
I
Krawiecka
D
D
D004352:Drug Resistance, Microbial; D006190:Haemophilus / Q000145:classification / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D008826:Microbial Sensitivity Tests; D011044:Poland; D013045:Species Specificity; D001618:beta-Lactamases / Q000378:metabolism
D001618:beta-Lactamases
Oporność Haemophilus sp. na antybiotyki.