title: [Intracytoplasmic sperm injection in the management of male infertility and idiopathic fertilization failure].
abstract: OBJECTIVE
  To demonstrate the efficacy of intracytoplasmic sperm injection (ICSI) in treatment male infertility and idiopathic fertilization failure.
  
  
  METHODS
  31 couples received intracytoplasmic sperm injections because of severe oligo-astheno-teratospermia or idiopathic infertility. Ovarian stimulation was achieved by conventional protocol. Transvaginal ultrasound-guided oocyte collections were done 36 hours after hCG injection. Only matured oocytes were selected for microinjection.
  
  
  RESULTS
  237 oocytes were treated by intracytoplasmic sperm injection; normal fertilization and cleavage occurred in 132 of 213 oocytes which were survived (62.0% normal fertilization rate). From 1995 to 1996, clinical pregnancies were achieved in 8 cases (25.8%). The first ICSI baby was delivered on October 3, 1996.
  
  
  CONCLUSIONS
  Intracytoplasmic sperm injection has improved the results of IVF-ET treatment in male and idiopathic infertility.
authors.affiliation: Assisted Reproductive Technique Center, First Affiliated Hospital of Sun Yet-Sen University of Medical Sciences, Guangzhou.
authors.forename: R
authors.initials: R
authors.lastname: Li
authors.forename: G
authors.initials: G
authors.lastname: Zhuang
authors.forename: M
authors.initials: M
authors.lastname: Zhang
mesh_terms: D000328:Adult; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007247:Infertility, Female / Q000628:therapy*; D007248:Infertility, Male / Q000628:therapy*; D008297:Male; D008845:Microinjections; D009865:Oocytes; D013094:Spermatozoa