title: [Lipid peroxidation and the antioxidant system of patients with urolithiasis after extracorporeal lithotripsy].
abstract: Activity of superoxide dismutase (SOD) in red cell membranes, levels of malonic dialdehyde (MDA) and dienic conjugates (DC) in blood plasma, red cells and urine were studied in 53 nephrolithiasis patients. A session of extracorporeal shock wave lithotripsy stimulated lipid peroxidation (LPO) in renal parenchyma manifesting with increased DC excretion with urine (an 89% increase). In red cell membranes SOD activity fell by 18%, DMA concentration rose by 16%. A two-week intake of vitamin E in a dose 100 mg/day elevated plasma alpha-tocopherol, diminished plasma MDA by 55% and prevented LPO activation in red cell membranes and renal parenchyma.
authors.forename: S A
authors.initials: SA
authors.lastname: Golovanov
authors.forename: E K
authors.initials: EK
authors.lastname: Ianenko
authors.forename: N K
authors.initials: NK
authors.lastname: Dzeranov
authors.forename: V V
authors.initials: VV
authors.lastname: Drozhzheva
authors.forename: D A
authors.initials: DA
authors.lastname: Beĭshliev
authors.forename: T A
authors.initials: TA
authors.lastname: Kon'kova
mesh_terms: D000975:Antioxidants / Q000378:metabolism*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007669:Kidney Calculi / Q000097:blood* / Q000628:therapy*; D015227:Lipid Peroxidation; D008096:Lithotripsy; D008297:Male; D014810:Vitamin E / Q000008:administration & dosage / Q000097:blood
chemical_list: D000975:Antioxidants; D014810:Vitamin E
vernacular_title: Lipidnaia peroksidatsiia i antioksidantnaia sistema u bol'nykh mochekamennoĭ bolezn'iu posle distantsionnoĭ litotripsii.