title: [A management for severe acquired stuttering in a case of pure akinesia syndrome].
abstract: We reported a 73-year-old man with pure akinesia syndrome who showed severe acquired stuttering and paradoxical kinesia on speech. He was evaluated in another hospital for bradykinesia and frozen gait at age of 67 when his cranial MRI disclosed ischemic changes in bilateral basal ganglia and periventricular deep white matter. The treatment with L-dopa and L-threo DOPS was not effective. His symptoms were slowly progressive and got worse gradually. At age of 72, he began to have difficulty in speech due to severe acquired stuttering, and one year later, he visited our hospital. The diagnosis of pure akinesia syndrome was made because of akinesia, micrographia, marked frozen gait with paradoxical kinesia and disturbance of postural reflex without tremor and rigidity. His speech showed severe acquired stuttering with marked blocking and repetition of initial phonemes at the beginning of speech. But intelligible speech recurred with pointing the characters by his finger or with writing an initial letter of word, although his speech was small and monotonous. Surface EMG findings of muscles participating speech in acquired stuttering showed the similar tonic discharge to those of muscles of lower extremity in frozen gait. These results implied that freezing phenomenon and festination of muscles participating speech in our patient may result in acquired stuttering.
authors.affiliation: Department of Medicine, Showa University Fujigaoka Hospital.
authors.forename: S
authors.initials: S
authors.lastname: Shibuya
authors.forename: Y
authors.initials: Y
authors.lastname: Wakayama
authors.forename: M
authors.initials: M
authors.lastname: Murahashi
authors.forename: K
authors.initials: K
authors.lastname: Aoki
authors.forename: Y
authors.initials: Y
authors.lastname: Ozasa
mesh_terms: D000368:Aged; D001921:Brain / Q000473:pathology; D004576:Electromyography; D005684:Gait; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009069:Movement Disorders / Q000150:complications* / Q000503:physiopathology; D018482:Muscle, Skeletal / Q000503:physiopathology; D012021:Reflex, Abnormal; D013342:Stuttering / Q000209:etiology*; D013577:Syndrome