Growth hormone and placental lactogen: biology, medicine and biotechnology.
Molecular cloning gave us access to the gene members of the human growth hormone and placental lactogen multigene family. Genomic sequencing provided clues for the understanding of the origin, functioning and regulation of this family. It has also allowed us to develop new diagnostic approaches for deficiencies of these hormones and to make new biotechnological contributions.
Barrera-Saldaña
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Departamento de Bioquímica, Facultad de Medicina, U.A.N.L. Av. Madero y Dr. Eduardo Aguirre Pequeño, Col. Mitras Centro, C.P. 64460, Monterrey, N.L., Mexico. hbarrera@uanl.mx
D019143:Evolution, Molecular; D005786:Gene Expression Regulation / Q000235:genetics; D013006:Growth Hormone / Q000235:genetics / Q000502:physiology*; D006801:Humans; D009154:Mutation / Q000235:genetics; D010928:Placental Lactogen / Q000235:genetics / Q000502:physiology*; D016133:Polymerase Chain Reaction / Q000379:methods; D015202:Protein Engineering; D011994:Recombinant Proteins / Q000302:isolation & purification; D017421:Sequence Analysis
D011994:Recombinant Proteins; D013006:Growth Hormone; D010928:Placental Lactogen