Substance P receptor (NK1)-immunoreactive neurons projecting to the periaqueductal gray: distribution in the spinal trigeminal nucleus and the spinal cord of the rat.
Substance P receptor (SPR)-immunoreactive neurons projecting to the periaqueductal gray (PAG) were examined in the rat spinal trigeminal nucleus and spinal cord by a retrograde tracing method combined with immunofluorescence histochemistry. After injection of Fluoro-gold (FG) into the PAG, SPR-immunoreactive neurons labeled with FG were observed mainly in the lateral spinal nucleus and lamina I of the medullary and spinal dorsal horns and additionally in laminae V and X of the spinal cord.
Li
J L
JL
Department of Anatomy and K. K. Leung Brain Research Centre, Fourth Military Medical University, Xi'an, People's Republic of China.
Ding
Y Q
YQ
Xiong
K H
KH
Li
J S
JS
Shigemoto
R
R
Mizuno
N
N
D000818:Animals; D019084:Fluorescent Antibody Technique, Indirect; D007150:Immunohistochemistry; D008297:Male; D009474:Neurons / Q000737:chemistry* / Q000276:immunology; D010487:Periaqueductal Gray / Q000737:chemistry* / Q000276:immunology; D051381:Rats; D017208:Rats, Wistar; D018040:Receptors, Neurokinin-1 / Q000032:analysis*; D013116:Spinal Cord / Q000737:chemistry* / Q000276:immunology; D014279:Trigeminal Nucleus, Spinal / Q000737:chemistry* / Q000276:immunology
D018040:Receptors, Neurokinin-1