title: Pericardial effusion and AIDS: benefits of surgical drainage.
abstract: OBJECTIVE
  During the last few years, AIDS has been the main cause of large pericardial effusions in urban settings. We have therefore had to perform surgical pericardial drainage for diagnostic and/or therapeutic purposes in AIDS patients. This study was designed to establish the diagnostic and therapeutic yield of pericardial drainage for these patients.
  
  
  METHODS
  We retrospectively reviewed the data of the 13 AIDS patients with a pericardial effusion, referred to our surgical department between December 1989 and December 1996 for surgical drainage and pericardial biopsy.
  
  
  RESULTS
  Cytological studies and searches for bacteria, mycobacteria and parasites were all negative. The histology of the 13 pericardial biopsies disclosed three pericardial locations of a Kaposi's sarcoma (all three patients had a pre-existent extra-cardiac location of this sarcoma) and one pericardial location of an already known immature mediastinal teratoma. In the nine other cases, the lesions were aspecific. Four patients died of multivisceral failure within 30 days of surgery. For the survivors, surgical drainage afforded relief and there were no clinical signs of recurrent effusion.
  
  
  CONCLUSIONS
  The cause of pericardial effusion in AIDS is still often unknown, even after pericardial biopsy. Here, aspecific pericarditis was the most common diagnosis. Although the prognosis of such effusion in these patients is known to be poor, surgical drainage provided relief for those who survived the post-operative period.
authors.affiliation: Vascular and Thoracic Surgery Department, Assistance Publique Tenon Hospital, Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Gouny
authors.forename: C
authors.initials: C
authors.lastname: Lancelin
authors.forename: P M
authors.initials: PM
authors.lastname: Girard
authors.forename: C
authors.initials: C
authors.lastname: Hocquet-Cheynel
authors.forename: W
authors.initials: W
authors.lastname: Rozenbaum
authors.forename: O
authors.initials: O
authors.lastname: Nussaume
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000150:complications*; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D010490:Pericardial Effusion / Q000000981:diagnostic imaging / Q000209:etiology / Q000601:surgery*; D010493:Pericarditis / Q000150:complications; D012189:Retrospective Studies; D016896:Treatment Outcome; D014463:Ultrasonography