title: [Brain metastases from papillary thyroid carcinoma: a case report and review of the literature].
abstract: Papillary carcinoma, the commonest thyroid malignancy, has a good prognosis and low incidence of distant metastases. Brain metastasis is extremely rare with a frequency of about 1% in reported series. In this paper we present the clinical details of one case of histologically proven brain metastasis from papillary thyroid cancer, first presented with neurological symptoms, initially treated with excisional biopsy and radiotherapy in other hospital, without clinical response. The patient was then referred to our service, where he underwent a total thyroidectomy and modified radical neck dissection, with the aim of posterior radioactive iodine treatment for the brain lesion. Unfortunately, he died of neurological complications, two months after the neck treatment. Also presented is a review of the literature of this unusual clinical presentation.
authors.affiliation: Disciplina de Cirurgia de Cabeça, Pescoço do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo.
authors.forename: R A
authors.initials: RA
authors.lastname: Altimari-Romero
authors.forename: F L
authors.initials: FL
authors.lastname: Montenegro
authors.forename: P
authors.initials: P
authors.lastname: Michaluart Júnior
authors.forename: D
authors.initials: D
authors.lastname: De Carlucci
authors.forename: L R
authors.initials: LR
authors.lastname: Medina-Santos
authors.forename: A R
authors.initials: AR
authors.lastname: Ferraz
mesh_terms: D001932:Brain Neoplasms / Q000175:diagnosis / Q000556:secondary*; D002291:Carcinoma, Papillary / Q000175:diagnosis / Q000556:secondary*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000473:pathology*
vernacular_title: Metástase cerebral de carcinoma papilífero de tireóide como apresentação inicial da doença: relato de caso e revisão da literatura.