title: Confocal imaging of gene expression during hamster submandibular gland biogenesis.
abstract: The data presented here provide evidence that the abundance of the ALG7 protein product, GPT, correlates with high proliferative activity during the postnatal development of the hamster SMG development, and that it becomes downregulated with differentiation. Based on our previous studies with yeast, changes in the level of ALG7 expression may be necessary for the events directing salivary cell polarization, migration, differentiation, and apoptosis at distinct developmental stages.
authors.affiliation: Division of Oral Biology, Boston University Goldman School of Dental Medicine, Massachusetts 02118, USA.
authors.forename: R
authors.initials: R
authors.lastname: Fernandes
authors.forename: M
authors.initials: M
authors.lastname: Fox
authors.forename: D
authors.initials: D
authors.lastname: Cotanche
authors.forename: K
authors.initials: K
authors.lastname: Lennon
authors.forename: M A
authors.initials: MA
authors.lastname: Kukuruzinska
mesh_terms: D000818:Animals; D006224:Cricetinae; D015870:Gene Expression; D007150:Immunohistochemistry; D018613:Microscopy, Confocal; D013363:Submandibular Gland / Q000201:enzymology / Q000254:growth & development*; D017855:Transferases (Other Substituted Phosphate Groups) / Q000096:biosynthesis* / Q000235:genetics
chemical_list: D017855:Transferases (Other Substituted Phosphate Groups); C023222:UDPacetylglucosamine-dolichyl-phosphate acetylglucosamine-1-phosphate transferase