Distribution of human platelet antigens in a Chinese population.
We report the distribution of the human platelet antigens HPA-1, -2, -3, -4 and -5 as determined using the polymerase chain reaction with sequence-specific primers in 100 random, healthy Chinese in Hong Kong. The HPA-1a, -2a, -4a and -5a genes were present in every sample tested, HPA-1b, -2b and -5b were rare, and the sample was monomorphic for HPA-4a. HPA-3a and -3b genes showed frequencies of 0.525 and 0.475 respectively. There was no departure from Hardy-Weinberg equilibrium in any of the five HPA systems studied.
Chang
Y W
YW
Department of Pathology, The University of Hong Kong, Hong Kong.
Mytilineos
J
J
Opelz
G
G
Hawkins
B R
BR
D016824:Antigens, Human Platelet / Q000145:classification / Q000235:genetics*; D044466:Asian People / Q000235:genetics*; D006801:Humans; D016133:Polymerase Chain Reaction; D011153:Population
D016824:Antigens, Human Platelet