title: [Familial metachromatic leukodystrophy as a cause of psychotic manifestations in young adults].
abstract: Cases of metachromatic leucodystrophy in brother and sister are presented. The clinical pattern in the female was characterised by the progressing dementia, whereas in the male the first symptom was the manic syndrome. The neurological status was normal. The cases were diagnosed by the demyelination visible in MRI pattern and in the decreased activity of arylsulphatase A in blood leukocytes.
authors.affiliation: Zespołu Neuroimmunologii Instytutu Centrum Medycyny Doświadczalnej i Klinicznej PAN.
authors.forename: M
authors.initials: M
authors.lastname: Wender
authors.forename: D
authors.initials: D
authors.lastname: Pruchnik-Wolińska
authors.forename: W
authors.initials: W
authors.lastname: Paprzycki
authors.forename: B
authors.initials: B
authors.lastname: Czartoryska
mesh_terms: D000328:Adult; D001714:Bipolar Disorder / Q000175:diagnosis / Q000209:etiology*; D001921:Brain / Q000473:pathology; D003704:Dementia / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D007966:Leukodystrophy, Metachromatic / Q000235:genetics* / Q000473:pathology / Q000523:psychology*; D008279:Magnetic Resonance Imaging; D010375:Pedigree; D011569:Psychiatric Status Rating Scales
vernacular_title: Rodzinna leukodystrofia metachromatyczna jako przyczyna zaburzeń psychicznych u młodych osób dorosłych.