[Neovascularization of pre-formed tissue flaps in relation to arteriovenous blood flow of the implanted vascular pedicle. Experimental study in the rabbit].
In 45 Chinchilla-Bastard rabbits, a skeletonised arterio-venous pedicle was implanted on the subsurface of a 15 x 8 cm abdominal skinflap to create a neovascularised axial prefabricated flap. In order to evaluate the potency of neovascularisation in relation to the blood flow of the pedicle, we compared minimal blood flow by distal ligation (model 1) with maximal blood flow by distal microvascular arteriovenous shunt anastomoses (model 2) of the implanted vascular pedicle. The results show that 8 and 12 days after pedicle implantation, tissue flap perfusion in model 2 is significantly earlier and better in comparison to model 1.
Klöppel
M
M
Abteilung für Plastische und Wiederherstellungschirurgie, Technische Universität München.
Nguyen
T H
TH
Graf
P
P
Laubenbacher
C
C
Höhnke
C
C
Schwaiger
M
M
Biemer
E
E
D000714:Anastomosis, Surgical; D000792:Angiography; D000818:Animals; D001783:Blood Flow Velocity / Q000502:physiology; D008833:Microcirculation / Q000502:physiology; D008866:Microsurgery / Q000379:methods*; D018919:Neovascularization, Physiologic / Q000502:physiology*; D011817:Rabbits; D013524:Surgical Flaps / Q000098:blood supply*
Die Neovaskularisation im präformierten Gewebelappen in Abhängigkeit vom arteriovenösen Blutfluss des implantierten Gefässstieles. Experimentelle Untersuchung am Kaninchen.