Susceptibilities of neonatal respiratory isolates of Ureaplasma urealyticum to antimicrobial agents.
Twenty-one neonatal respiratory isolates of Ureaplasma urealyticum were serotyped, and their susceptibilities to ciprofloxacin, gentamicin, chloramphenicol, erythromycin, azithromycin, and doxycycline were tested. Most patient strains were Ureaplasma urealyticum bv. parvum. Chloramphenicol, doxycycline, and azithromycin had the lowest MICs. This data may be useful when designing prophylactic or therapeutic trials of antibiotics for chronic lung disease of the newborn.
Matlow
A
A
Department of Pediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada. anne.matlow@mailhub.sickkids.on.ca
Th'ng
C
C
Kovach
D
D
Quinn
P
P
Dunn
M
M
Wang
E
E
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D017963:Azithromycin / Q000494:pharmacology; D002701:Chloramphenicol / Q000494:pharmacology; D004318:Doxycycline / Q000494:pharmacology; D006801:Humans; D007231:Infant, Newborn; D008171:Lung Diseases / Q000188:drug therapy / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D012137:Respiratory System / Q000382:microbiology*; D016869:Ureaplasma Infections / Q000188:drug therapy / Q000382:microbiology; D016990:Ureaplasma urealyticum / Q000187:drug effects* / Q000302:isolation & purification
D000900:Anti-Bacterial Agents; D002701:Chloramphenicol; D017963:Azithromycin; D004318:Doxycycline