title: Interplay of matrices in cartilage synovial fluid combine under moderate & high loadings.
abstract: Interplay of the constituents of the articular cartilage synovial fluid combine and its role was examined through the biochemical and rheological studies on bovine joints. The results showed an inverse relationship between the changes in the hyaluronic acid of synovial fluid and the proteoglycans content in articular cartilage together with alterations in the rheological properties of synovial fluid. The study indicated that the inter-movement of fluid solutes across the cartilage and synovial fluid may have an important role in the pathophysiology of osteoarthritis.
authors.affiliation: Centre for Biomedical Engineering, All India Institute of Medical Sciences, New Delhi.
authors.forename: R K
authors.initials: RK
authors.lastname: Saxena
authors.forename: K
authors.initials: K
authors.lastname: Agarwal
authors.forename: K B
authors.initials: KB
authors.lastname: Sahay
authors.forename: S K
authors.initials: SK
authors.lastname: Guha
authors.forename: P K
authors.initials: PK
authors.lastname: Dave
mesh_terms: D000818:Animals; D002358:Cartilage, Articular / Q000378:metabolism*; D002417:Cattle; D005260:Female; D012212:Rheology; D013582:Synovial Fluid / Q000378:metabolism*