Practical synthesis of (2s,3s)-3-amino-2-hydroxy-4-phenylbutyric acid, a key component of HIV protease inhibitors.
Shibata
N
N
Sagami Chemical Research Center, Sagamihara, Kanagawa, Japan.
Itoh
E
E
Terashima
S
S
D019380:Anti-HIV Agents / Q000138:chemical synthesis*; D002219:Carbamates; D005663:Furans; D017320:HIV Protease Inhibitors / Q000138:chemical synthesis; D009570:Nitriles / Q000737:chemistry; D009842:Oligopeptides / Q000138:chemical synthesis; D010654:Phenylbutyrates / Q000138:chemical synthesis*; D013237:Stereoisomerism; D013449:Sulfonamides / Q000138:chemical synthesis
D019380:Anti-HIV Agents; D002219:Carbamates; D005663:Furans; D017320:HIV Protease Inhibitors; D009570:Nitriles; D009842:Oligopeptides; D010654:Phenylbutyrates; D013449:Sulfonamides; C077823:kynostatin 227; C095108:amprenavir; C034940:3-amino-2-hydroxy-4-phenylbutanoic acid; C010833:acetone cyanohydrin; C077822:kynostatin 272