title: [Pathological examination of 10 eyes with silicone oil injection].
abstract: OBJECTIVE
  To find the histopathologic findings about 10 eyes of 10 patients with silicone oil injection.
  
  
  METHODS
  The operative procedures included retinal detachment surgery, pars plana vitrectomy and silicone oil injection. The globes were enucleated 4 to 27 months after silicone oil injection. Paraffin sections were made for light microscopic examination.
  
  
  RESULTS
  The retina showed severe degeneration, pre- and sub-retinal membranous fibrous tissue proliferation. The round empty vacuoles formed by silicone oil could be seen in the proliferative membrane.
  
  
  CONCLUSIONS
  It is demonstrated that silicone oil has great toxic effect to the detached retina and it may stimulate the development of proliferative vitreoretinopathy.
authors.affiliation: Department of Ophthalmology, Third Hospital, Beijing Medical University.
authors.forename: W
authors.initials: W
authors.lastname: Wang
authors.forename: H
authors.initials: H
authors.lastname: Zhang
authors.forename: H
authors.initials: H
authors.lastname: Schilling
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D012160:Retina / Q000473:pathology*; D012163:Retinal Detachment / Q000473:pathology* / Q000601:surgery; D012827:Silicone Oils / Q000009:adverse effects* / Q000627:therapeutic use; D014821:Vitrectomy; D018630:Vitreoretinopathy, Proliferative / Q000209:etiology / Q000473:pathology
chemical_list: D012827:Silicone Oils