title: Obstetrical anaesthesia for a parturient with preeclampsia, HELLP syndrome and acute cortical blindness.
abstract: OBJECTIVE
  To report the management of a multigravida presenting with preeclampsia, HELLP syndrome and acute cortical blindness for Caesarean section.
  
  
  METHODS
  A 39-yr-old woman, with three past uncomplicated pregnancies presented at 33 wk with acute cortical blindness. Based on clinical and laboratory assessment, a diagnosis of preeclampsia with HELLP syndrome was made. A CT scan of her head demonstrated ischaemic lesions of her basal ganglia, extending superiorly to involve both posterior parietal and occipital regions. Infusions of magnesium sulphate and hydralazine were started and an urgent Caesarean section was performed under subarachnoid anaesthesia after insertion of an arterial line and intravenous hydration. The course of anaesthesia and surgery was uneventful and she delivered a live 1540 g female infant. By the following morning, she had recovered some vision and visual recovery was complete by 72 hr postpartum. She underwent an MRI with angiography on the first postpartum day. Ischaemic lesions were confirmed in the same sites identified on CT scan but all major cerebral vessels were patent and no significant vascular abnormality was noted. Her postoperative course was uneventful and she was discharged home seven days postpartum after being prescribed labetalol for continued hypertension.
  
  
  CONCLUSIONS
  The anaesthetic management of a parturient with acute cortical blindness and HELLP syndrome is modeled on the underlying preeclamptic condition. Invasive monitoring is not routinely indicated but is specifically indicated in some cases. Provided that it is not contraindicated because of prohibitive risk to the mother, regional anaesthesia has particular advantage in these patients. In particular, the use of spinal anaesthesia, which has been discouraged by some for this patient population, should be re-evaluated.
authors.affiliation: Department of Anaesthesia, University of Ottawa, Ottawa General Hospital, Ontario. ecrosby@fox.nstn.ca
authors.forename: E T
authors.initials: ET
authors.lastname: Crosby
authors.forename: R
authors.initials: R
authors.lastname: Preston
mesh_terms: D000208:Acute Disease; D000328:Adult; D000773:Anesthesia, Obstetrical; D019575:Blindness, Cortical / Q000209:etiology*; D005260:Female; D017359:HELLP Syndrome / Q000209:etiology*; D006801:Humans; D007231:Infant, Newborn; D011225:Pre-Eclampsia / Q000150:complications*; D011247:Pregnancy