Localization of Chlamydia trachomatis heat shock proteins 60 and 70 during infection of a human endometrial epithelial cell line in vitro.
Unlike chlamydial lipopolysaccharide, which is released from the developing inclusion to the surface of infected genital epithelial cells, both Chlamydia trachomatis heat shock protein (hsp) 60 and 70 antigens remained confined within the inclusion during the course of the chlamydial developmental cycle. Exposure of the infected cells to penicillin to induce a persistent infection or to a lipophilic microbicide did not potentiate secretion or exocytosis of the chlamydial hsp.
Raulston
J E
JE
Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill 27599-7290, USA.
Paul
T R
TR
Knight
S T
ST
Wyrick
P B
PB
D001426:Bacterial Proteins / Q000032:analysis*; D002460:Cell Line; D018834:Chaperonin 60 / Q000032:analysis*; D002692:Chlamydia trachomatis / Q000737:chemistry*; D004717:Endometrium / Q000737:chemistry / Q000382:microbiology*; D004847:Epithelial Cells / Q000737:chemistry / Q000382:microbiology; D005260:Female; D018840:HSP70 Heat-Shock Proteins / Q000032:analysis*; D006801:Humans
D001426:Bacterial Proteins; D018834:Chaperonin 60; D018840:HSP70 Heat-Shock Proteins