title: Reading within the lines: naturally processed peptides displayed by MHC class I molecules.
abstract: A typical mammalian cell contains tens of thousands of different gene products. Snippets of this genetic information are displayed on the cell surface by MHC class I molecules as short peptides for immune surveillance by CD8+ T lymphocytes. Genetic and biochemical analysis of these peptides is revealing novel sources and mechanisms by which these peptide/MHC class I complexes arise.
authors.affiliation: Department of Molecular and Cell Biology, University of California, Berkeley 94720-3200, USA. nshastri@socrates.berkeley.edu
authors.forename: N
authors.initials: N
authors.lastname: Shastri
authors.forename: T
authors.initials: T
authors.lastname: Serwold
authors.forename: P
authors.initials: P
authors.lastname: Paz
mesh_terms: D017951:Antigen Presentation / Q000276:immunology; D015395:Histocompatibility Antigens Class I / Q000276:immunology*; D006801:Humans; D010455:Peptides / Q000276:immunology*
chemical_list: D015395:Histocompatibility Antigens Class I; D010455:Peptides