title: Anti-nociceptive and anti-inflammatory effects of some Jordanian medicinal plant extracts.
abstract: The anti-nociceptive effect of ethanolic extract of 11 traditionally used Jordanian plants was studied by using the acetic acid-induced writhing and hot-plate test in mice. The anti-inflammatory effect of these plants was determined by xylene-induced ear oedema in mice and cotton pellet granuloma test in rats. Mentha piperita, Cinnamomum zeylanicum, Apium graveolens, Eucalyptus camaldulentis, and Ruta graveolens possess an anti-nociceptive effect against both acetic acid-induced writhing and hot plate-induced thermal stimulation. M. piperita, Jasminum officinale, Commiphora molmol, and Beta vulgaris possess an anti-inflammatory effect against acute (xylene-induced ear oedema) and chronic (cotton-pellet granuloma) inflammation. The anti-nociceptive and anti-inflammatory effects were dose dependent. These data affirm the traditional use of some of these plants for painful and inflammatory conditions.
authors.affiliation: Department of Veterinary Basic Sciences, Faculty of Veterinary Medicine, Jordan University of Science and Technology, Irbid.
authors.forename: A H
authors.initials: AH
authors.lastname: Atta
authors.forename: A
authors.initials: A
authors.lastname: Alkofahi
mesh_terms: D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D000431:Ethanol; D007597:Jordan; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats
chemical_list: D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D010936:Plant Extracts; D000431:Ethanol