title: [Prevalence of hepatitis C virus and excessive consumption of alcohol in a nonhospital worker population].
abstract: The aim of the study was to know the prevalence of the hepatitis C virus (HCV) in a non hospital work population by ELISA 3.0 and PCR-Amplicor, as well as its relationship with excessive alcohol intake (more than 280 g/week in men and 168 g/week in women). A transversal seroepidemiologic study was carried out in 1,109 workers of the Empresa Nacional de Electricidad, S.A. (ENDESA). During the annual medical examinations (April 1993-October 1994) the amount of alcoholic beverages each worker had consumed over the 7 days prior to the medical examination was obtained by anamnesis together with a blood sample for different laboratory tests. Sixteen percent of the workers had had excessive alcohol intake. The prevalence of anti HCV antibodies in the study population was 2.4% being up to 4.6% in the workers declaring excessive alcohol consumption and 10.4% if they also presented an elevation in any of the transaminases. The prevalence of the potentially ineffective workers was 1.46%. The prevalence of anti C antibodies by ELISA 3.0 was greater than expected (2.4%) significantly increasing in the population group which declared excessive alcohol intake, thereby demonstrating the relationship between alcohol and hepatitis C.
authors.affiliation: Servicios Médicos de Empresa Nacional de Electricidad, Universidad Complutense de Madrid.
authors.forename: J J
authors.initials: JJ
authors.lastname: Prieto Domingo
authors.forename: J A
authors.initials: JA
authors.lastname: Carrión Bolaños
authors.forename: F
authors.initials: F
authors.lastname: Bandrés Moya
mesh_terms: D000328:Adult; D000428:Alcohol Drinking; D000437:Alcoholism / Q000150:complications; D001803:Blood Transfusion; D018592:Cross-Over Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006526:Hepatitis C / Q000453:epidemiology / Q000276:immunology*; D018937:Hepatitis C Antibodies / Q000032:analysis*; D006801:Humans; D015151:Immunoblotting; D008297:Male; D008875:Middle Aged; D009790:Occupations; D016133:Polymerase Chain Reaction; D015995:Prevalence; D013030:Spain / Q000453:epidemiology
chemical_list: D018937:Hepatitis C Antibodies
vernacular_title: Prevalencia del virus de la hepatitis C y consumo excesivo de alcohol en una población laboral no hospitalaria.