[Prognosis of residual spleen after partial splenic embolization for the treatment of hypersplenism in cirrhosis].
The aim of this study was to elusidate the change in residual spleen volume after partial splenic embolization (PSE) in 43 cirrhotic patients with marked hypersplenism. Residual spleen volume was indicated as the rate (%) of residual spleen to initial spleen before PSE. Furthermore, the platelet count after PSE was observed in 23 patients followed up for 2 years. Residual spleen volume in patients with infarction rates of more than 80% (group A) had been maintained within 20 % even after 2 years, while they had obviously increased during the early stage after PSE in patients with infarction rates under 80% (group B), especially in patients with lower infarction rates (under 60%). Mean platelet count improved significantly in both groups after PSE (p < 0.001, respectively), but increased more in group A than in group B (p < 0.01). High fever and abdominal pain were observed in all cases of PSE. Other adverse effects such as pleural effusion and ascites that were frequent in group A were transient. These results suggest that PSE performed with a high infarction rate of the spleen provides effective, long-lasting results in the treatment of hypersplenism in cirrhosis.
Iida
T
T
Department of Radiology, Saiseikai Yahata General Hospital.
Sakino
I
I
Akagi
K
K
D004621:Embolization, Therapeutic / Q000379:methods; D005260:Female; D006801:Humans; D006971:Hypersplenism / Q000209:etiology / Q000628:therapy*; D008103:Liver Cirrhosis / Q000150:complications*; D008297:Male; D011379:Prognosis; D013154:Spleen / Q000000981:diagnostic imaging*; D014057:Tomography, X-Ray Computed