title: Clinical and histologic trends of melanoma.
abstract: BACKGROUND
  Several changing clinical and histopathologic melanoma trends occurred from the 1950s to the 1980s.
  
  
  OBJECTIVE
  The purpose of this study was to evaluate melanoma trends during the past decade and to compare present trends to those documented during the past four decades.
  
  
  METHODS
  Sex, age at diagnosis, location, tumor thickness, stage, and histologic subtypes were evaluated from 1984 to 1995 and compared with trends during the past four decades.
  
  
  RESULTS
  Most changing trends from the past four decades have slowed or stabilized during the past decade.
  
  
  CONCLUSIONS
  Complete reporting of all melanomas to central tumor registries is necessary to accurately analyze present and future melanoma trends. Ongoing and new prevention and control strategies beginning at birth may be necessary to continue the positive efforts to curtail the melanoma epidemic.
authors.affiliation: Department of Dermatology, University of Michigan Medical Center, Ann Arbor, USA.
authors.forename: T M
authors.initials: TM
authors.lastname: Johnson
authors.forename: O M
authors.initials: OM
authors.lastname: Dolan
authors.forename: T A
authors.initials: TA
authors.lastname: Hamilton
authors.forename: M C
authors.initials: MC
authors.lastname: Lu
authors.forename: N A
authors.initials: NA
authors.lastname: Swanson
authors.forename: L
authors.initials: L
authors.lastname: Lowe
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D016009:Chi-Square Distribution; D004196:Disease Outbreaks / Q000517:prevention & control; D005260:Female; D005544:Forecasting; D006258:Head and Neck Neoplasms / Q000453:epidemiology / Q000473:pathology; D006801:Humans; D018327:Hutchinson's Melanotic Freckle / Q000453:epidemiology / Q000473:pathology / Q000517:prevention & control; D008297:Male; D008545:Melanoma / Q000145:classification / Q000453:epidemiology / Q000473:pathology* / Q000517:prevention & control; D018328:Melanoma, Amelanotic / Q000453:epidemiology / Q000473:pathology / Q000517:prevention & control; D008875:Middle Aged; D009367:Neoplasm Staging / Q000145:classification; D012042:Registries; D012737:Sex Factors; D012878:Skin Neoplasms / Q000145:classification / Q000453:epidemiology / Q000473:pathology* / Q000517:prevention & control; D013899:Thoracic Neoplasms / Q000453:epidemiology / Q000473:pathology; D014481:United States / Q000453:epidemiology