[Role of the lawc(p1) mutation in the regulation of the white locus expression in Drosophila].
The lawcp1 mutation of the leg-arista-wing complex (lawc) gene alters expression of three proneural loci: achaete, scute, and cut. In combination with the product of the zeste (z) gene, the product of the lawc gene regulates expression of the white (w) gene. The -w B3 mutation was genetically analyzed in compounds with various z and w mutations and dominant mutations modifying the z-w interaction. The results showed that lawcp1 can enhance the transvection effect. The lawc gene was assumed to regulate expression of the white locus at the level of chromatin condensation.
Simonova
O B
OB
Institute of Gene Biology, Russian Academy of Sciences, Moscow, Russia. olga@neuro.biogen.msk.su
Petruk
S F
SF
Dzhagaeva
I V
IV
Korochkin
L I
LI
D000818:Animals; D004330:Drosophila / Q000235:genetics*; D005127:Eye Color / Q000235:genetics*; D005260:Female; D005786:Gene Expression Regulation / Q000502:physiology*; D005799:Genes, Dominant; D017344:Genes, Insect; D008297:Male; D010641:Phenotype; D017354:Point Mutation
Rol' mutatsii lawc(p1) v reguliatsii ékspressii lokusa white u drozofily.