[The modulating effects of preparations of Baikal skullcap (Scutellaria baicalensis) on erythron reactions under conditions of neurotic exposures].
Preparations of Scutellaria baicalensis, namely its dry extract and the bioflavonoid baicalin stimulate erythropoiesis depressed in deprivation of the paradoxical phase of sleep. After a conflict situation, when hemopoiesis is activated, both drugs normalize it. The modulating effect of drugs on hemopoiesis in exposure to neurotic factors is a consequence of their influence on the functional state of the cell elements of the hemopoiesis-inducing microenvironment. The capacity of the Scutellaria baicalensis drugs for reducing the effect of psychoemotional stress on the blood system is apparently related to their influence on the adrenergic structures.
Dygaĭ
A M
AM
Institute of Pharmacology, Tomsk Research Center, Russian Academy of Medical Sciences, Russia.
Suslov
N I
NI
Skurikhin
E G
EG
Churin
A A
AA
Provalova
N V
NV
D000818:Animals; D001854:Bone Marrow Cells / Q000187:drug effects; D004195:Disease Models, Animal; D004353:Drug Evaluation, Preclinical; D004920:Erythropoiesis / Q000187:drug effects*; D005419:Flavonoids / Q000494:pharmacology / Q000627:therapeutic use; D008297:Male; D051379:Mice; D008808:Mice, Inbred CBA; D009497:Neurotic Disorders / Q000097:blood / Q000188:drug therapy* / Q000209:etiology; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use; D010946:Plants, Medicinal / Q000737:chemistry*; D013268:Stimulation, Chemical
D005419:Flavonoids; D010936:Plant Extracts; C038044:baicalin
Moduliruiushchie éffekty preparatov shlemnika baĭkal'skogo na reaktsii éritrona v usloviiakh nevroticheskikh vozdeĭstviĭ.