Pindolol augmentation of sertraline in resistant depression and its effect on sleep.
A case is reported of a 34-year-old lady with a 2-year history of resistant depression who responded to pindolol augmentation of sertraline. It also illustrates the use of sleep electroencephalogram measures as a way of assessing changes in brain 5-hydroxytryptamine function.
Bell
C
C
Psychopharmacology Unit, School of Medical Sciences, Bristol, UK.
Wilson
S
S
Nutt
D J
DJ
D015057:1-Naphthylamine / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000328:Adult; D000928:Antidepressive Agents / Q000627:therapeutic use*; D001921:Brain / Q000378:metabolism; D003863:Depression / Q000188:drug therapy* / Q000378:metabolism; D004357:Drug Synergism; D004569:Electroencephalography; D005260:Female; D006801:Humans; D010869:Pindolol / Q000627:therapeutic use*; D012701:Serotonin / Q000378:metabolism; D020280:Sertraline; D012890:Sleep / Q000187:drug effects*
D000319:Adrenergic beta-Antagonists; D000928:Antidepressive Agents; D012701:Serotonin; D015057:1-Naphthylamine; D010869:Pindolol; D020280:Sertraline