Cholinergic structures and neuropathologic alterations in the olfactory bulb of Alzheimer's disease brain samples.
This report describes the laminar distribution of acetylcholinesterase-positive structures and the neuropathologic alterations in the human olfactory bulb of control and Alzheimer's disease brain samples. The results suggests that no correlation exists between the distribution of cholinergic axons and the neuropathological alterations in the different layers in Alzheimer's disease.
Kovacs
I
I
Alzheimer's Disease Research Center, Albert Szent-Györgyi Medical University, Szeged, Hungary. kimre@comser.szote.u-szeged.hu
Torok
I
I
Zombori
J
J
Kasa
P
P
D000110:Acetylcholinesterase / Q000378:metabolism; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000473:pathology*; D000682:Amyloid / Q000378:metabolism; D000818:Animals; D001921:Brain / Q000378:metabolism / Q000473:pathology*; D002799:Cholinergic Fibers / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D016874:Neurofibrillary Tangles / Q000473:pathology; D009830:Olfactory Bulb / Q000473:pathology*; D058225:Plaque, Amyloid / Q000473:pathology; D051381:Rats; D017207:Rats, Sprague-Dawley; D012016:Reference Values; D014018:Tissue Distribution
D000682:Amyloid; D000110:Acetylcholinesterase