title: Detection of nasopharyngeal carcinoma with head and neck Tc-99m tetrofosmin SPECT imaging.
abstract: Tc-99m tetrofosmin SPECT imaging of the head and neck was performed on 10 patients with nasopharyngeal carcinoma (NPC) and 10 controls. There was no abnormal nasopharyngeal uptake of tetrofosmin in the 10 controls. In the patients with NPC, 3/10 (30%) of the cases had no abnormal uptake and 7/10 (70%) had increased nasopharyngeal uptake. Considering our preliminary study, we find that Tc-99m tetrofosmin SPECT of the head and neck may be helpful in the detection of NPC. However, further study with a larger number of patients is needed to ascertain the value of Tc-99m tetrofosmin SPECT in such cases.
authors.affiliation: Department of Nuclear Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan, Republic of China.
authors.forename: Y Y
authors.initials: YY
authors.lastname: Shen
authors.forename: C H
authors.initials: CH
authors.lastname: Kao
authors.forename: S P
authors.initials: SP
authors.lastname: Changlai
authors.forename: P U
authors.initials: PU
authors.lastname: Chieng
authors.forename: T C
authors.initials: TC
authors.lastname: Yen
mesh_terms: D000328:Adult; D001706:Biopsy; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006257:Head / Q000000981:diagnostic imaging; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007275:Injections, Intravenous; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D009305:Nasopharynx / Q000000981:diagnostic imaging; D009333:Neck / Q000000981:diagnostic imaging; D009943:Organophosphorus Compounds / Q000008:administration & dosage; D015609:Organotechnetium Compounds / Q000008:administration & dosage; D019275:Radiopharmaceuticals / Q000008:administration & dosage; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; D019275:Radiopharmaceuticals; C078700:technetium tc-99m tetrofosmin