[Natural cytokine complex as a drug bioregulator in healing of alkaline burns of cornea (experimental morphological study)].
Clinical morphological features of reparative processes of alkaline burns of the cornea are studied in 24 rabbits. Effects of the natural cytokine complex on this process are validated. Burn process is regarded as an immune inflammation. Morphological and morphometric data demonstrate the mechanism of the cytokine effect on the reparative processes in the cornea, based on the regulation of the inflammatory postburn and proliferative processes. The repair of the cornea after burn in experiment and control is described in detail.
Khoroshilova-Maslova
I P
IP
Gankovskaia
L V
LV
Ilatovskaia
L V
LV
Chavla
R
R
Rodygina
T V
TV
Bakhtulova
M E
ME
D000287:Administration, Topical; D000468:Alkalies / Q000009:adverse effects; D000818:Animals; D002057:Burns, Chemical / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D002455:Cell Division; D002682:Chinchilla; D003315:Cornea / Q000187:drug effects* / Q000276:immunology / Q000473:pathology; D016207:Cytokines / Q000008:administration & dosage / Q000627:therapeutic use*; D004195:Disease Models, Animal; D005126:Eye Burns / Q000139:chemically induced* / Q000276:immunology / Q000473:pathology; D005347:Fibroblasts / Q000187:drug effects / Q000473:pathology; D005500:Follow-Up Studies; D008214:Lymphocytes / Q000276:immunology / Q000473:pathology; D008264:Macrophages / Q000276:immunology / Q000473:pathology; D009883:Ophthalmic Solutions; D011817:Rabbits; D016896:Treatment Outcome; D014945:Wound Healing / Q000187:drug effects / Q000502:physiology*
D000468:Alkalies; D016207:Cytokines; D009883:Ophthalmic Solutions
Estestvennyĭ kompleks tsitokinov kak lekarstvennyĭ bioreguliator pri zazhivlenii shchelochnykh ozhogov rogovitsy (éksperimental'no-morfologicheskoe issledovanie).