title: del 11(q23) as a prognostic factor of iron overload in refractory anemia with ringed sideroblasts.
abstract: We present the case of a patient with MDS RARS subtype with loss of part of the long arm of chromosome 11 del 11(q23). This a cytogenetic abnormality that occurs in 7% to 20% of RARS cases not related to poor prognosis. It seems that this deletion is a marker of iron overload in MDS.
authors.affiliation: Disciplina de Hematologia e Hemoterapia, Escola Paulista de Medicina-UNIFESP, Brazil.
authors.forename: M de L
authors.initials: Mde L
authors.lastname: Chauffaille
authors.forename: J T
authors.initials: JT
authors.lastname: Stéfano
authors.forename: R M
authors.initials: RM
authors.lastname: Valério
authors.forename: M
authors.initials: M
authors.lastname: Romeo
authors.forename: M M
authors.initials: MM
authors.lastname: Rodrígues
authors.forename: J
authors.initials: J
authors.lastname: Kerbauy
mesh_terms: D000753:Anemia, Refractory / Q000235:genetics*; D000756:Anemia, Sideroblastic / Q000235:genetics*; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D002880:Chromosomes, Human, Pair 11; D005260:Female; D006801:Humans; D019190:Iron Overload / Q000235:genetics*; D008875:Middle Aged; D011379:Prognosis