[Experimental study on repair of mandibular defect by allogenic decalcified bone compounded with autogeneic bone marrow in rabbits].
Twenty adult rabbits were used in our experiment. The bone defects were made at the lower border of the bilateral mandible. A compound bone graft (allogenic decalcified bone with autogeneic bone marrow, ADB) was implanted in the right bone defect as the experimental group. The left mandible was taken as the control group and autogeneic cancellous bone was grafted. The process of new bone formation was evaluated by X-ray plain film, 99Tc-PYP Scintigraphy, histological, and histochemical, and transmmission electronic microscope examinations. The results demonstrated histogically that ADB induced new bone formation. The quantity of new bone produced by compound bone graft in the experimental group was much more than that in control group (P < 0.05). The compound bone graft can promote and accelerate bone defect healing.
Li
Y
Y
Stomatological Hospital, China Medical University, Shenyang.
Yang
Y
Y
Yan
L
L
D000818:Animals; D018775:Bone Demineralization Technique; D016026:Bone Marrow Transplantation; D016025:Bone Transplantation; D003648:Decalcification Technique; D008334:Mandible / Q000601:surgery*; D010012:Osteogenesis; D011817:Rabbits