title: [Secondary head and neck osteosarcoma following treatment of undifferentiated nasopharyngeal neoplasms (UCNT)].
abstract: Secondary tumours after radio and/or chemotherapy are mainly of hematopoietic (acute non lymphoblastic leukemia, non-Hodgkin lymphoma) or soft tissue lineage previously described most frequently after breast cancer and Hodgkin disease treatment with radio and/or chemotherapy. We report two cases of classical osteosarcoma's observed 9 and 3 years after treatment for UCNT with combined radiotherapy and alkylant-based adjuvant chemotherapy in one case and exclusive loco-regional irradiation in the second case.
authors.affiliation: Institut Salah Azaïz, Bab Saadoun, Tunis, Tunisie.
authors.forename: H
authors.initials: H
authors.lastname: Boussen
authors.forename: S
authors.initials: S
authors.lastname: Gritli
authors.forename: S
authors.initials: S
authors.lastname: Touati
authors.forename: A
authors.initials: A
authors.lastname: Chebbi
authors.forename: H
authors.initials: H
authors.lastname: Krichen
authors.forename: F
authors.initials: F
authors.lastname: Benna
authors.forename: A
authors.initials: A
authors.lastname: Saadi
authors.forename: A
authors.initials: A
authors.lastname: el May
authors.forename: F
authors.initials: F
authors.lastname: Ben Ayed
authors.forename: A
authors.initials: A
authors.lastname: Ladgham
mesh_terms: D000328:Adult; D002277:Carcinoma / Q000473:pathology / Q000628:therapy*; D002648:Child; D003131:Combined Modality Therapy; D017809:Fatal Outcome; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D006801:Humans; D009303:Nasopharyngeal Neoplasms / Q000473:pathology / Q000628:therapy*; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D012516:Osteosarcoma / Q000175:diagnosis / Q000556:secondary* / Q000628:therapy; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy / Q000009:adverse effects*
vernacular_title: Ostéosarcome secondaire de la tête et du cou après traitement de carcinome indifférencié du nasopharynx (UCNT).