[Effect of hormone replacement therapy on postmenopausal ocular function].
OBJECTIVE
Determination of the effects of hormonal replacement therapy (HRT) on various ocular parameters and symptoms in postmenopausal women.


METHODS
Prospective study.


METHODS
Department of Obstetrics and Gynecology, University "Federico II" of Naples.


METHODS
14 healthy women treated orally with equine conjugated estrogen in continuous (0,625 mg/daily) and acetate-medroxyprogesteron (10 mg/daily) from 17th to 28th day for three months.


METHODS
Ocular symptomatology, intraocular pressure (IOP), lacrimal secretion, reflected and basal and corneal thickness.


RESULTS
After 3 months of HRT the IOP was reduced of 10.8% (p < 0.005), the lacrimal secretion, reflected and basal, increased of 19% and 48%, respectively and the corneal thickness increased of 16.6%.


CONCLUSIONS
The HRT has a positive effect on ocular physiology.
Sorrentino
C
C
Facoltà di Medicina e Chirurgia, Cattedra di Ostetricia e Ginecologia, Università degli Studi Federico II, Napoli.
Affinito
P
P
Mattace Raso
F
F
Loffredo
M
M
Merlino
P
P
Loffredo
A
A
Palomba
S
S
Nappi
C
C
D000368:Aged; D003315:Cornea / Q000187:drug effects; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D007765:Lacrimal Apparatus / Q000187:drug effects; D008875:Middle Aged; D009799:Ocular Physiological Phenomena / Q000187:drug effects*
Effetti della terapia ormonale sostitutiva sulla funzionalità oculare in postmenopausa.