title: Cutaneous angiosarcoma of the face: clinicopathologic and immunohistochemical study of a case resembling rosacea clinically.
abstract: An unusual cutaneous angiosarcoma resembling rosacea clinically is described. A 66-year-old man presented with a red discoloration and a diffuse swelling on his nose over a 2-year period that was diagnosed as rosacea. Despite antiinflammatory treatment, the infiltration increased and, after repeated skin biopsies, the diagnosis of a well-differentiated cutaneous angiosarcoma associated with a prominent inflammatory infiltrate was considered. The neoplasm was treated by surgery. The described case emphasizes that diffuse swelling and rosacea-like clinical features should be added to the variably clinical features of cutaneous angiosarcoma.
authors.affiliation: Institute of Pathology, University of Jena, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Mentzel
authors.forename: H
authors.initials: H
authors.lastname: Kutzner
authors.forename: U
authors.initials: U
authors.lastname: Wollina
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001706:Biopsy; D002467:Cell Nucleus / Q000648:ultrastructure; D003937:Diagnosis, Differential; D004730:Endothelium, Vascular / Q000473:pathology; D005169:Factor VIII / Q000032:analysis; D006394:Hemangiosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D007150:Immunohistochemistry; D008214:Lymphocytes / Q000473:pathology; D008297:Male; D009669:Nose Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000032:analysis; D012393:Rosacea / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery
chemical_list: D000893:Anti-Inflammatory Agents; D019408:Platelet Endothelial Cell Adhesion Molecule-1; D005169:Factor VIII