Endovascular papillary angioendothelioma (Dabska tumor) in an elderly woman.
A patient with endovascular papillary angioendothelioma with a low grade of malignancy showing papillary proliferation of endothelioid cells is presented. The patient, an 83-year-old woman, underwent resection of a tumor of the neck. At operation a 9 x 7 cm cystic tumor containing yellow transparent liquid with clots was found in the subcutaneous tissue. Histological studies showed endothelioid cells with spindle-shaped nuclei proliferated in layers around the fibrovascular cores, which showed the characteristic appearance of papillary proliferation. These cells were immunohistochemically positive for CD31, CD34 and factor VIII-related antigen. Based on these observations, the tumor was considered to be an endovascular papillary angioendothelioma (Dabska tumor). Dabska tumor is a vascular tumor with a low grade of malignancy and usually occurs in infants and young children. About 13 cases of Dabska tumor have been reported. The occurrence of a Dabska tumor in an aged patient is considered to be rare.
Yamada
A
A
Department of Pathology (Hospital), Hyogo College of Medicine, Nishinomiya, Japan.
Uematsu
K
K
Yasoshima
H
H
Sakurai
K
K
Hori
K
K
Ohya
M
M
Ohkubo
E
E
Ogasawara
H
H
D000368:Aged; D000369:Aged, 80 and over; D018952:Antigens, CD34 / Q000378:metabolism; D017809:Fatal Outcome; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology*; D006390:Hemangioendothelioma / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000378:metabolism; D014057:Tomography, X-Ray Computed
D018952:Antigens, CD34; D019408:Platelet Endothelial Cell Adhesion Molecule-1