title: The significance of angiogenesis in guided bone regeneration. A case report of a rabbit experiment.
abstract: A dome-shaped bioresorbable membrane was fixed to the wounded rabbit calvaria and filled with a bioresorbable fibre conglomerate. After 4 weeks, the histologic preparation revealed an intimate spatial and temporal correlation between newly formed blood vessels and de novo extraskeletal bone formation. These observations emphasize the significance of angiogenesis in guided bone generation.
authors.affiliation: Department of Periodontology and Fixed Prosthodontics, University of Berne, Switzerland.
authors.forename: J
authors.initials: J
authors.lastname: Schmid
authors.forename: B
authors.initials: B
authors.lastname: Wallkamm
authors.forename: C H
authors.initials: CH
authors.lastname: Hämmerle
authors.forename: S
authors.initials: S
authors.lastname: Gogolewski
authors.forename: N P
authors.initials: NP
authors.lastname: Lang
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D001861:Bone Regeneration / Q000502:physiology*; D001842:Bone and Bones / Q000098:blood supply*; D048091:Guided Tissue Regeneration; D019344:Lactic Acid; D008567:Membranes, Artificial; D018919:Neovascularization, Physiologic; D011091:Polyesters; D011108:Polymers; D011817:Rabbits; D012886:Skull / Q000601:surgery
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial; D011091:Polyesters; D011108:Polymers; D019344:Lactic Acid; C033616:poly(lactide)