title: [The relation between coronary vasospasm and coronary obstructive lesions in patients with variant angina].
abstract: A series of 38 patients with variant angina in whom coronary arteriography was performed was reviewed to investigate the relation between coronary vasospasm and coronary obstructive lesions. 10 of the 38 (26.3%) patients had completely normal coronary arteriograms; 4 (10.5%) had insignificant coronary artery disease (< 50% stenosis); 24 (63.2%) had significant (> or = 50% stenosis) coronary artery disease, including single vessel disease in 12 cases, multiple vessel disease in 11 cases and left main trunk disease in one case. The results of this study showed that the incidence of coronary vasospasm increased with the severity of coronary stenosis and was highest at 75%-90% stenosis of the ischemia-related artery in those patients with significant coronary disease. In this study of 38 patients, coronary vasospasm involved the left anterior descending artery (LAD) in 25 patients (65.8%), right coronary artery (RCA) in 10 (26.3%) and left circumflex artery (LCX) in 2 (5.3%), but in patients with in significant stenosis (< 50%), LAD was involved in 50.0%, RCA in 42.9% and LCX in 7.1%. These results indicate that coronary vasospasm occurs frequently in patients with severe stenosis of the LAD.
authors.affiliation: Cardiovascular Institute of the Chinese Academy of Medical Sciences, Fu Wai Cardiovascular Hospital, Beijing.
authors.forename: J
authors.initials: J
authors.lastname: Chen
authors.forename: R
authors.initials: R
authors.lastname: Gao
authors.forename: K
authors.initials: K
authors.lastname: Yao
mesh_terms: D000328:Adult; D000788:Angina Pectoris, Variant / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D000790:Angiocardiography; D003329:Coronary Vasospasm / Q000150:complications*; D003331:Coronary Vessels / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged