title: [Diabetic foot--uncontrollable infections despite successful revascularization].
abstract: We treated foot ulcerations in diabetics with limb-threatening ischemia using percutaneous balloon dilatation (44) and popliteodistal vein grafts (94). After revascularization, we observed in 12% an increase in the infection which necessitated major amputation despite open bypass or successful dilatation. A diabetic local immunodeficiency leads to cellular and humoral alterations which may cause severe tissue damage although the perfusion has been improved.
authors.affiliation: Klinik für Gefäss- und Thoraxchirurgie, Zentralklinikum, Augsburg.
authors.forename: C
authors.initials: C
authors.lastname: Wack
authors.forename: K D
authors.initials: KD
authors.lastname: Wölfle
authors.forename: H
authors.initials: H
authors.lastname: Häuser
authors.forename: K
authors.initials: K
authors.lastname: Bohndorf
authors.forename: H
authors.initials: H
authors.lastname: Loeprecht
mesh_terms: D000368:Aged; D000671:Amputation, Surgical; D000800:Angioplasty, Balloon; D001166:Arteriovenous Shunt, Surgical; D003131:Combined Modality Therapy; D017719:Diabetic Foot / Q000276:immunology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005528:Foot / Q000098:blood supply*; D006801:Humans; D007108:Immune Tolerance / Q000276:immunology; D007511:Ischemia / Q000276:immunology / Q000601:surgery*; D008297:Male; D012086:Reoperation; D017211:Treatment Failure; D014680:Veins / Q000637:transplantation*; D014946:Wound Infection / Q000209:etiology / Q000601:surgery*
vernacular_title: Der diabetische Fuss--nicht beherrschbare Infektionen trotz erfolgreicher Revaskularisation.