Isopoly-L-ornithine derivative as nucleic acid model.
Isopoly-L-ornithine derivatives of thymine, and thymidine were found to hardly interact with poly A. Conformational studies of the oligomers with CD and NMR revealed that stable intramolecular hydrogen bonding was formed between the thymine base and the ornithine unit.
Inaki
Y
Y
Materials and Life Science, Graduate School of Osaka University, Japan.
Tohnai
N
N
Miyabayashi
K
K
Miyata
M
M
D004247:DNA / Q000737:chemistry; D006860:Hydrogen Bonding; D007536:Isomerism; D008958:Models, Molecular; D008961:Models, Structural; D009690:Nucleic Acid Conformation; D010455:Peptides / Q000737:chemistry*; D011061:Poly A / Q000737:chemistry*; D011487:Protein Conformation; D012313:RNA / Q000737:chemistry; D013936:Thymidine; D013941:Thymine
D010455:Peptides; D011061:Poly A; C008973:polyornithine; D012313:RNA; D004247:DNA; D013941:Thymine; D013936:Thymidine