No circadian variation of dihydropyrimidine dehydrogenase, uridine phosphorylase, beta-alanine, and 5-fluorouracil during continuous infusion of 5-fluorouracil.
Van Kuilenburg
A B
AB
Department Clinical Chemistry, Academic Medical Center, University of Amsterdam, The Netherlands.
Poorter
R L
RL
Peters
G J
GJ
Van Gennip
A H
AH
Van Lenthe
H
H
Stroomer
A E
AE
Smid
K
K
Noordhuis
P
P
Bakker
P J
PJ
Veenhof
C H
CH
D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage / Q000097:blood* / Q000627:therapeutic use; D002940:Circadian Rhythm; D015179:Colorectal Neoplasms / Q000097:blood / Q000188:drug therapy*; D042943:Dihydrouracil Dehydrogenase (NADP); D005472:Fluorouracil / Q000008:administration & dosage / Q000097:blood* / Q000627:therapeutic use; D006801:Humans; D007262:Infusions, Intravenous; D007963:Leukocytes, Mononuclear / Q000201:enzymology*; D010088:Oxidoreductases / Q000097:blood*; D012044:Regression Analysis; D014543:Uridine Phosphorylase / Q000097:blood*; D015091:beta-Alanine / Q000097:blood*
D000964:Antimetabolites, Antineoplastic; D015091:beta-Alanine; D010088:Oxidoreductases; D042943:Dihydrouracil Dehydrogenase (NADP); D014543:Uridine Phosphorylase; D005472:Fluorouracil