title: Advances in periodontal diagnosis. 7. Proteolytic and hydrolytic enzymes link with periodontitis.
abstract: Biomarkers of periodontal disease activity may be obtained from potential proteolytic and hydrolytic enzymes of inflammatory cell origin. Studies that have sought to correlate these enzymes with periodontal disease activity are reviewed with special consideration given to collagenases, cysteine, aspartate and serine proteinases, beta-glucuronidase, arylsulphate, alkaline and acid phosphatases, myeloperoxidase, lysozyme and lactoferrin.
authors.affiliation: Department, King's College School of Medicine and Dentistry, Denmark Hill, London.
authors.forename: B M
authors.initials: BM
authors.lastname: Eley
authors.forename: S W
authors.initials: SW
authors.lastname: Cox
mesh_terms: D000135:Acid Phosphatase / Q000032:analysis; D000469:Alkaline Phosphatase / Q000032:analysis; D001192:Arylsulfatases / Q000032:analysis; D016282:Aspartic Acid Endopeptidases / Q000032:analysis; D015415:Biomarkers / Q000032:analysis; D017364:Collagenases / Q000032:analysis; D003546:Cysteine Endopeptidases / Q000032:analysis; D005966:Glucuronidase / Q000032:analysis; D006801:Humans; D006867:Hydrolases / Q000032:analysis*; D007781:Lactoferrin / Q000032:analysis; D009113:Muramidase / Q000032:analysis; D010447:Peptide Hydrolases / Q000032:analysis*; D010510:Periodontal Diseases / Q000175:diagnosis* / Q000201:enzymology; D010518:Periodontitis / Q000175:diagnosis / Q000201:enzymology*; D009195:Peroxidase / Q000032:analysis; D012697:Serine Endopeptidases / Q000032:analysis
chemical_list: D015415:Biomarkers; D009195:Peroxidase; D006867:Hydrolases; D000469:Alkaline Phosphatase; D000135:Acid Phosphatase; D001192:Arylsulfatases; D009113:Muramidase; D005966:Glucuronidase; D010447:Peptide Hydrolases; D007781:Lactoferrin; D012697:Serine Endopeptidases; D003546:Cysteine Endopeptidases; D016282:Aspartic Acid Endopeptidases; D017364:Collagenases