title: Component release from light-activated glass ionomer and compomer cements.
abstract: The purpose of this study was to identify and quantify any component released from seven commercially available light-cured or resin-modified glass ionomer and compomer cements. Twenty-one separate cylindrical stainless steel moulds 6 mm in diameter and 1.0 mm deep were filled with one of seven glass ionomer or compomer cements, light activated and then immediately immersed in separate containers of distilled water. Water samples were retrieved over a time period of up to 30 days and retained for analysis. An occlusal cavity 6 mm in diameter was prepared in extracted human third molar teeth with a remaining dentin thickness of 1.6-2.0 mm. A polypropylene chamber was attached to the cemento-enamel junction of each tooth to contain 1 mL of distilled water. Ten teeth were each filled with one of three cements and light activated. Water samples (eluates) were retrieved over a period of time. All samples were analysed by high performance liquid chromatography. Only one component, hydroxyethyl methacrylate (HEMA), was detected in the eluates from both tooth and mould samples. Analysis of diffusion of the HEMA through dentin showed a relatively sustained movement into the pulp space during the first day, with exponential decline thereafter. Our data show that HEMA was released from all of the light activated glass ionomer cements studied and from the compomer, both directly into water and through dentin. This release may be relevant both to the risk of adverse pulpal responses in patients and to the risk of allergy in patients and dental personnel.
authors.affiliation: Department of Resorative Dentistry, University of California, San Francisco, CA, USA.
authors.forename: A
authors.initials: A
authors.lastname: Hamid
authors.forename: A
authors.initials: A
authors.lastname: Okamoto
authors.forename: M
authors.initials: M
authors.lastname: Iwaku
authors.forename: W R
authors.initials: WR
authors.lastname: Hume
mesh_terms: D002851:Chromatography, High Pressure Liquid; D003188:Composite Resins / Q000009:adverse effects / Q000032:analysis / Q000737:chemistry*; D003782:Dental Pulp / Q000187:drug effects / Q000378:metabolism; D003793:Dental Restoration, Permanent; D003804:Dentin / Q000378:metabolism; D004058:Diffusion; D005899:Glass Ionomer Cements / Q000009:adverse effects / Q000032:analysis / Q000737:chemistry*; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology; D007101:Immersion; D008027:Light; D008689:Methacrylates / Q000009:adverse effects / Q000032:analysis / Q000737:chemistry; D008964:Molar, Third / Q000378:metabolism; D019279:Resin Cements / Q000009:adverse effects / Q000032:analysis / Q000737:chemistry*; D012307:Risk Factors; D013997:Time Factors; D019237:Tooth Cervix / Q000378:metabolism; D014867:Water
chemical_list: D003188:Composite Resins; D005899:Glass Ionomer Cements; D008689:Methacrylates; D019279:Resin Cements; D014867:Water; C005044:hydroxyethyl methacrylate