title: Comparison of substance P concentration in acupuncture points in different tissues in dogs.
abstract: Histologically, acupuncture points show neuronal innervation. One hundred seventy-seven tissue samples of acupuncture points and control points from 4 dogs were collected. Concentrations of substance P, a neurotransmitter, in the skin, muscle and subcutis of acupuncture points and control points were measured by means of enzyme immunoassay. The determined tissue concentrations of substance P (mean +/- SEM) in acupuncture points and control points were 1.81 +/- 0.13 and 1.51 +/- 0.1 ng/g in the muscle, 3.33 +/- 0.29 and 2.63 +/- 0.28 ng/g in the skin and 1.59 +/- 0.22 and 1.32 +/- 0.16 ng/g in the subcutis, respectively. The results indicate that there is a difference in the neurochemical profile between acupuncture points and control points.
authors.affiliation: Institut für Medizinische Chemie, Veterinarmedizinische Universität Wien, Vienna, Austria.
authors.forename: W W
authors.initials: WW
authors.lastname: Chan
authors.forename: H
authors.initials: H
authors.lastname: Weissensteiner
authors.forename: W D
authors.initials: WD
authors.lastname: Rausch
authors.forename: K Y
authors.initials: KY
authors.lastname: Chen
authors.forename: L S
authors.initials: LS
authors.lastname: Wu
authors.forename: J H
authors.initials: JH
authors.lastname: Lin
mesh_terms: D015669:Acupuncture Points; D000818:Animals; D004285:Dogs; D005260:Female; D008297:Male; D009132:Muscles / Q000378:metabolism; D012867:Skin / Q000378:metabolism; D013373:Substance P / Q000378:metabolism*
chemical_list: D013373:Substance P