title: CT angiography of potential renal transplant donors.
abstract: Renal transplantation has grown rapidly over the past 30 years, resulting in an inadequate supply of organs to meet the ever-increasing demand. This has led to an increase in the number of living-related donors. Advances in imaging technology now allow safe, rapid, and relatively noninvasive evaluation of potential donors. Helical computed tomographic (CT) angiography is a fast, minimally invasive procedure that is quickly becoming the imaging modality of choice for preoperative evaluation of potential renal transplant donors. Helical CT, combined with low-osmolar intravenous contrast materials, has enabled CT angiography to depict arterial and venous anatomy accurately. Between July 1995 and March 1997, CT angiography was performed in 205 potential renal donors. Correlation with surgical findings in 136 donor nephrectomies helped confirm a high level of accuracy for CT angiography in the assessment of the renal vasculature: Sensitivity and specificity for identifying specific vessels was 99.6% and 99.6% for main renal arteries, 76.9% and 89.9% for polar arteries, and 98.7% and 95.5% for main renal veins, respectively. CT angiography allows the radiologist to provide the transplant surgeon with precise preoperative anatomy of the renal vasculature, thus reducing the risks and complications associated with the harvesting procedure and improving the chances for a successful outcome. However, accurate radiologic interpretation depends on the radiologist's experience level, attention to detail, and commitment to careful image evaluation.
authors.affiliation: Department of Radiology, University of Wisconsin Medical School, Madison 53792-3252, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Pozniak
authors.forename: D J
authors.initials: DJ
authors.lastname: Balison
authors.forename: F T
authors.initials: FT
authors.lastname: Lee
authors.forename: R H
authors.initials: RH
authors.lastname: Tambeaux
authors.forename: D T
authors.initials: DT
authors.lastname: Uehling
authors.forename: T D
authors.initials: TD
authors.lastname: Moon
mesh_terms: D000792:Angiography / Q000379:methods*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007668:Kidney / Q000098:blood supply* / Q000000981:diagnostic imaging*; D007674:Kidney Diseases / Q000000981:diagnostic imaging; D016030:Kidney Transplantation; D019520:Living Donors; D008297:Male; D011857:Radiographic Image Interpretation, Computer-Assisted; D012077:Renal Artery / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D012082:Renal Veins / Q000033:anatomy & histology / Q000000981:diagnostic imaging; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*