[Does the biocompatibility of the hemodialysis membrane influence the prognosis of acute renal insufficiency?].
Several recent publications have suggested that the use of cuprophane in the setting of acute renal failure is associated with a higher mortality (especially from sepsis) and a slower recovery of renal function in the survivors in comparison with more biocompatible membranes. We present here a critical review of these publications and point to several methodological bias that might invalidate their conclusions. However, while waiting further information, we would advocate to abandon the use of cuprophane to dialyze patients with acute renal failure.
Tielemans
C
C
Cliniques universitaires de Bruxelles, Hôpital Erasme, Université Libre de Bruxelles.
Gastaldello
K
K
Melot
C
C
Kahn
R J
RJ
Vanherweghem
J L
JL
D058186:Acute Kidney Injury / Q000401:mortality* / Q000628:therapy; D001672:Biocompatible Materials; D002482:Cellulose / Q000031:analogs & derivatives; D006801:Humans; D008567:Membranes, Artificial; D011379:Prognosis; D006435:Renal Dialysis / Q000295:instrumentation*
D001672:Biocompatible Materials; D008567:Membranes, Artificial; D002482:Cellulose; C009865:cuprammonium cellulose
La biocompatibilité de la membrane d'hémodialyse influence-t-elle le pronostic de l'insuffisance rénale aiguë?