title: Imidazolium triflate as an efficient promoter for O-selective phosphitylation of N-unprotected nucleosides via the phosphoramidite approach.
abstract: A novel method for the preparation of nucleotides via the phosphoramidite approach with imidazolium triflate 1 as a promoter has been developed. This approach required no protecting groups for nucleoside bases of building blocks.
authors.affiliation: Laboratory of Bioorganic Chemistry, Graduate School of Human Informatics, Nagoya University, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kataoka
authors.forename: S
authors.initials: S
authors.lastname: Heidenhain
authors.forename: Y
authors.initials: Y
authors.lastname: Hayakawa
mesh_terms: D015195:Drug Design; D015394:Molecular Structure; D009705:Nucleosides; D009711:Nucleotides / Q000138:chemical synthesis*; D009943:Organophosphorus Compounds
chemical_list: D009705:Nucleosides; D009711:Nucleotides; D009943:Organophosphorus Compounds