title: Preoperative features of patients with exfoliation glaucoma and primary open-angle glaucoma. The AHEPA study.
abstract: OBJECTIVE
  To describe and compare the preoperative characteristics of Greek patients with exfoliation glaucoma (EXG) and primary open-angle glaucoma (POAG).
  
  
  METHODS
  We prospectively investigated the preoperative features of 100 consecutive patients undergoing filtration surgery for either EXG, or POAG. We compared 74 patients with EXG and 26 with POAG.
  
  
  RESULTS
  EXG patients were older (68.2 vs 62.4 years; p<0.05) and more often from the countryside (73%). Both glaucomas showed a preponderance for males, similar frequencies of positive family history and systemic disorders, with the exception of diabetes which was more common in POAG (19.2% vs 5.4%). The first IOP measurement, before treatment, was significantly higher in EXG (40.4 mm Hg) compared with POAG (33.9 mm Hg). Despite a shorter duration of medical therapy (25 vs 65 months) and more topical drugs EXG patients exhibited higher mean preoperative IOP (36 vs 27.8 mm Hg for POAG; p<0.05). EXG patients had significantly worse visual acuity than POAG (0.4 vs 0.6; p<0.05) and worse compliance to medical therapy (48%) compared to POAG (33%).
  
  
  CONCLUSIONS
  Significant differences in preoperative features distinguish EXG from POAG.
authors.affiliation: Department of Ophthalmology, Aristotle University of Thessaloniki, Greece. konstas@med.auth.gr
authors.forename: A G
authors.initials: AG
authors.lastname: Konstas
authors.forename: I
authors.initials: I
authors.lastname: Tsatsos
authors.forename: A
authors.initials: A
authors.lastname: Kardasopoulos
authors.forename: T
authors.initials: T
authors.lastname: Bufidis
authors.forename: G
authors.initials: G
authors.lastname: Maskaleris
mesh_terms: D017677:Age Distribution; D000368:Aged; D017889:Exfoliation Syndrome / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology* / Q000601:surgery; D005260:Female; D018463:Filtering Surgery; D005902:Glaucoma, Open-Angle / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology* / Q000601:surgery; D006801:Humans; D015994:Incidence; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D011446:Prospective Studies; D012424:Rural Population; D017678:Sex Distribution; D014792:Visual Acuity / Q000502:physiology