title: [Description of a case of Reye's-like syndrome with fatal outcome].
abstract: A Reye Like Syndrome case occurred in a twelve year-old little girl with a previous familiar history is reported. The little patient was admitted in the pediatric ward for fever, vomiting and aspecific respiratory symptoms and developed very quickly a severe metabolic acidosis, alterations of consciousness, hypoxia, tissular hypoperfusion, multiple organ failure (MOF) and a fatal outcome. The postmortem diagnosis pointed out a methyl malonic acidaemia, a fairly frequent cause of acute metabolic distress, which may occur also in prepuberal age. The correct diagnostic and therapeutic approach of these cases is stressed since they need a prompt and careful monitoring in intensive care unit and a close cooperation among pediatricians, intensive care specialists and the nearest centre for the study of metabolic diseases.
authors.affiliation: Nuovo Ospedale San Giovanni di Dio, U.O. Anestesia-Rianimazione, Azienda Sanitaria di Firenze.
authors.forename: R
authors.initials: R
authors.lastname: Oggioni
authors.forename: R
authors.initials: R
authors.lastname: Iamello
authors.forename: G
authors.initials: G
authors.lastname: Tulli
mesh_terms: D002648:Child; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D012202:Reye Syndrome / Q000503:physiopathology*
vernacular_title: Descrizione di un caso di Reye like syndrome ad esito fatale.