title: Feeding lactating primiparous sows to establish three divergent metabolic states: I. Associated endocrine changes and postweaning reproductive performance.
abstract: We investigated effects of different metabolic states on reproductive performance in lactating, primiparous sows. Sows were fed ad libitum (AL; n = 12), alimentated via a gastric cannula to 125% of AL feed intake (SA; n = 8), or restricted (R; n = 9) to 50% of AL from d 1 to 28 of lactation. At weaning, all sows were fed 2.5x maintenance energy requirements until standing heat and then fed twice maintenance energy requirement until slaughter. Sow weight, backfat, and litter weights were recorded weekly. After weaning, sows were tested twice daily for the onset of estrus and inseminated twice using pooled semen. At d 28 of gestation, sows were slaughtered, and the reproductive tracts were recovered to determine ovulation rate and embryo survival. Intensive blood sampling was performed before and after weaning for 12-h periods to characterize changes in plasma LH, insulin, and IGF-I. After weaning, additional samples were taken to monitor changes in LH and progesterone. Insulin and IGF-I were determined at standing heat. During lactation, AL and R sows lost, whereas SA sows gained, body weight and backfat (P < .001). Litter growth rates did not differ among treatments. Although plasma insulin was not different among treatments, plasma IGF-I concentration was lower (P < .001) in R sows. Mean LH and pulse frequency before (P < .03 and P < .06, respectively) and after (P < .001; for both) weaning were lower in R than in AL or SA sows. After weaning, SA sows lost more weight (P < .01) and backfat (P < .01) and ate less feed (P < .001) than AL or R sows. At standing heat, no differences in plasma IGF-I or insulin were observed, although energy balance for SA sows was lower (P < .01) than for AL or R sows. Weaning-to-estrus interval was extended (P < .02) in R sows. We observed no treatment difference in ovulation rate or embryo survival. Our results demonstrate that making sows anabolic during lactation did not ameliorate the negative impact of the suckling stimulus or improve fertility after weaning.
authors.affiliation: Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada.
authors.forename: L J
authors.initials: LJ
authors.lastname: Zak
authors.forename: I H
authors.initials: IH
authors.lastname: Williams
authors.forename: G R
authors.initials: GR
authors.lastname: Foxcroft
authors.forename: J R
authors.initials: JR
authors.lastname: Pluske
authors.forename: A C
authors.initials: AC
authors.lastname: Cegielski
authors.forename: E J
authors.initials: EJ
authors.lastname: Clowes
authors.forename: F X
authors.initials: FX
authors.lastname: Aherne
mesh_terms: D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D002940:Circadian Rhythm / Q000502:physiology; D015331:Cohort Studies; D005260:Female; D007328:Insulin / Q000097:blood*; D007334:Insulin-Like Growth Factor I / Q000032:analysis*; D007774:Lactation / Q000097:blood / Q000378:metabolism*; D016018:Least-Squares Analysis; D007986:Luteinizing Hormone / Q000097:blood* / Q000378:metabolism; D010060:Ovulation / Q000502:physiology; D010298:Parity; D013552:Swine / Q000097:blood* / Q000378:metabolism / Q000502:physiology; D014886:Weaning
chemical_list: D007328:Insulin; D007334:Insulin-Like Growth Factor I; D007986:Luteinizing Hormone