title: The first reported case of intestinal spirochaetosis in Japan.
abstract: A 65-year-old Japanese male consulted Ozuchi Prefectural Hospital (Iwate, Japan) on 19 January 1994 complaining of weight loss. Cecal mucosal biopsy material, which was stained with hematoxylin-eosin revealed a thick, basophilic fuzzy fringe covering the surface epithelium. Transmission and scanning electron microscopy observations demonstrated the presence of slightly wavy spirochaetes with tapered ends, which were attached to the surface epithelium of the colonic mucosa via one of these ends. The patient did not display any clinical symptoms of inflammatory bowel disease, and laboratory tests eliminated an immunodeficiency condition. Thus, in the present case, the intestinal spirochaetes appear to be harmless commensals. This paper presents the first reported case of intestinal spirochaetosis in Japan.
authors.affiliation: Division of Pathology, School of Medicine, Iwate Medical University, Morioka, Japan. nakamurashin@jsn.justnet.or.jp
authors.forename: S
authors.initials: S
authors.lastname: Nakamura
authors.forename: T
authors.initials: T
authors.lastname: Kuroda
authors.forename: T
authors.initials: T
authors.lastname: Sugai
authors.forename: S
authors.initials: S
authors.lastname: Ono
authors.forename: T
authors.initials: T
authors.lastname: Yoshida
authors.forename: I
authors.initials: I
authors.lastname: Akasaka
authors.forename: F
authors.initials: F
authors.lastname: Nakashima
authors.forename: S
authors.initials: S
authors.lastname: Sasou
mesh_terms: D000368:Aged; D002429:Cecal Diseases / Q000469:parasitology* / Q000473:pathology; D006651:Histocytochemistry; D006801:Humans; D007564:Japan; D008297:Male; D008854:Microscopy, Electron; D008855:Microscopy, Electron, Scanning; D013144:Spirochaetales / Q000648:ultrastructure; D013145:Spirochaetales Infections / Q000473:pathology*