title: Emerging targets for the development of novel antifungal therapeutics.
abstract: Invasive mycoses have become important causes of morbidity and mortality in immunocompromised patients. New approaches for antifungal therapy are required to meet the challenges imposed by these life-threatening infections. Such approaches are being developed through identification of novel biochemical and molecular targets of pathogenic fungi.
authors.affiliation: Immunocompromised Host Section, National Cancer Institute, NIH, Bethesda, MD, USA.
authors.forename: A H
authors.initials: AH
authors.lastname: Groll
authors.forename: A J
authors.initials: AJ
authors.lastname: De Lucca
authors.forename: T J
authors.initials: TJ
authors.lastname: Walsh
mesh_terms: D000935:Antifungal Agents / Q000737:chemistry* / Q000494:pharmacology*; D002462:Cell Membrane / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism; D002473:Cell Wall / Q000737:chemistry / Q000187:drug effects; D004271:DNA, Fungal / Q000378:metabolism; D005656:Fungal Proteins / Q000096:biosynthesis; D010445:Peptide Elongation Factors / Q000096:biosynthesis; D015398:Signal Transduction
chemical_list: D000935:Antifungal Agents; D004271:DNA, Fungal; D005656:Fungal Proteins; D010445:Peptide Elongation Factors