[Beta trace protein in the cerebrospinal fluid and serum in meningoencephalitis].
BACKGROUND
beta-trace protein or D2 prostaglandin synthase is a dual functional protein. Its role and clinical value in cerebrospinal fluid is under study.


METHODS
Seventy four pediatric patients suffering from viral meningoencephalitis and 7 with bacterial meningoencephalitis were studied. Sera and cerebrospinal fluid samples were taken. Albumin and beta-trace protein were quantified by immunodiffusion and nephelometry respectively.


RESULTS
Increased cerebrospinal fluid beta-trace protein levels in comparison with normal value were observed. Nevertheless such expected increment was no possible seen in bacterial meningoencephalitis.


CONCLUSIONS
beta-trace protein may contribute with the etiological diagnosis in meningoencephalitis.
Dorta-Contreras
A J
AJ
Laboratorio de Neuroinmunología, Hospital Pediátrico San Miguel del Padrón, La Habana, Cuba.
Reiber
H
H
Agüero-Valdés
E
E
Interían-Morales
M T
MT
Mechulam-Cohen
A
A
Noris-García
E
E
D000418:Albumins / Q000134:cerebrospinal fluid; D001798:Blood Proteins / Q000032:analysis*; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis*; D002675:Child, Preschool; D003937:Diagnosis, Differential; D006801:Humans; D005779:Immunodiffusion / Q000379:methods; D008590:Meningoencephalitis / Q000097:blood* / Q000134:cerebrospinal fluid*; D009391:Nephelometry and Turbidimetry / Q000379:methods; D015230:Prostaglandin D2 / Q000097:blood* / Q000134:cerebrospinal fluid*; D011451:Prostaglandin-Endoperoxide Synthases / Q000097:blood* / Q000134:cerebrospinal fluid*; D012709:Serum Albumin / Q000032:analysis
D000418:Albumins; D001798:Blood Proteins; D002556:Cerebrospinal Fluid Proteins; D012709:Serum Albumin; D011451:Prostaglandin-Endoperoxide Synthases; D015230:Prostaglandin D2
Proteína beta traza en líquido cefalorraquídeo y suero en meningoencefalitis.