Extraskeletal uptake of technetium-99m-MDP in sites of heparin administration.
A 19-yr-old woman with juvenile diabetes and protein C deficiency was referred for a bone scan to rule out osteomyelitis of the right tibia. The bone scan did not reveal evidence of osteomyelitis. There was, however, extraskeletal uptake of the 99mTc bone tracer in the anterior abdominal wall confined to the sites of subcutaneous heparin administration. This case is presented because of its interesting scintigraphic findings and to discuss the association of protein C deficiency and heparin administration as a cause of extraskeletal 99mTc bone tracer accumulation.
Challa
S
S
Division of Nuclear Radiology, Childrens Hospital, Los Angeles, California 90027, USA.
Miller
J H
JH
D000009:Abdominal Muscles / Q000000981:diagnostic imaging*; D000328:Adult; D000925:Anticoagulants / Q000008:administration & dosage*; D001778:Blood Coagulation Disorders / Q000150:complications / Q000188:drug therapy; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D005260:Female; D006493:Heparin / Q000008:administration & dosage*; D006801:Humans; D007279:Injections, Subcutaneous; D010019:Osteomyelitis / Q000000981:diagnostic imaging; D020151:Protein C Deficiency; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate
D000925:Anticoagulants; D019275:Radiopharmaceuticals; D006493:Heparin; D013669:Technetium Tc 99m Medronate