title: Solid phase synthesis of benzamidine and butylamine-derived hydantoin libraries.
abstract: We have constructed a number of benzamidine- and butylamine-based hydantoin compounds by means of an efficient route using solid phase synthesis in which neat diisopropylamine was employed for a novel cyclization/traceless cleavage step. All library compounds were obtained in excellent yield and high purity.
authors.affiliation: Biotech Research Institute, LG Chemical Ltd., Science Town, Taejon, Korea.
authors.forename: S W
authors.initials: SW
authors.lastname: Kim
authors.forename: J S
authors.initials: JS
authors.lastname: Koh
authors.forename: E J
authors.initials: EJ
authors.lastname: Lee
authors.forename: S
authors.initials: S
authors.lastname: Ro
mesh_terms: D001550:Benzamidines / Q000138:chemical synthesis*; D002082:Butylamines / Q000378:metabolism; D006827:Hydantoins / Q000138:chemical synthesis*; D015394:Molecular Structure; D011437:Propylamines / Q000378:metabolism
chemical_list: D001550:Benzamidines; D002082:Butylamines; D006827:Hydantoins; D011437:Propylamines; C007442:diisopropylamine