title: Synthesis of stereoselectively 13C/2H-doubly labeled DNA oligomers by the combined use of chemical and enzymatic reactions.
abstract: (2'S,5'S)-(1',2',3',4',5'-13C5;2',5'-2H2-thymidine, prepared via labeled ribosyl thymidine as described in the accompanying paper, has been successfully converted into isotopically labeled dA, dG, and dC using enzymatic transdeoxyribosylation reactions.
authors.affiliation: Department of Chemistry, Faculty of Science, Tokyo Metropolitan University, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Ono
authors.forename: Y
authors.initials: Y
authors.lastname: Oogo
authors.forename: S
authors.initials: S
authors.lastname: Tate
authors.forename: A
authors.initials: A
authors.lastname: Ono
authors.forename: M
authors.initials: M
authors.lastname: Kainosho
mesh_terms: D002247:Carbon Isotopes; D004247:DNA / Q000138:chemical synthesis / Q000737:chemistry; D003903:Deuterium; D007202:Indicators and Reagents; D007553:Isotope Labeling / Q000379:methods; D009838:Oligodeoxyribonucleotides / Q000138:chemical synthesis* / Q000737:chemistry*; D013936:Thymidine
chemical_list: D002247:Carbon Isotopes; D007202:Indicators and Reagents; D009838:Oligodeoxyribonucleotides; D004247:DNA; D003903:Deuterium; D013936:Thymidine