title: Modelling cure rates using the Gompertz model with covariate information.
abstract: We extend the modified Gompertz hazard function, first used by Cantor and Shuster for estimation of cure rates from pediatric clinical trials, by including covariate effects. The extended model provides a convenient method for estimation of the cure rate as a function of treatments and covariates.
authors.affiliation: Pediatric Oncology Group Statistical Office, Gainesville, FL 32601-3330, USA.
authors.forename: P W
authors.initials: PW
authors.lastname: Gieser
authors.forename: M N
authors.initials: MN
authors.lastname: Chang
authors.forename: P V
authors.initials: PV
authors.lastname: Rao
authors.forename: J J
authors.initials: JJ
authors.lastname: Shuster
authors.forename: J
authors.initials: J
authors.lastname: Pullen
mesh_terms: D000465:Algorithms; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002648:Child; D006801:Humans; D016013:Likelihood Functions; D016014:Linear Models; D008432:Mathematical Computing; D015233:Models, Statistical; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000401:mortality / Q000628:therapy; D011379:Prognosis; D016032:Randomized Controlled Trials as Topic; D012044:Regression Analysis; D018709:Statistics, Nonparametric; D015996:Survival Rate; D016896:Treatment Outcome