Familial osteoma of the cranial vault.
A case of solitary osteoma of the parietal skull is described in a mother and her 12-year-old son. There were no other craniofacial or dysmorphic features and there was no history of previous cranial trauma or inflammatory process and no radiographic evidence of other skeletal lesions in both patients. Family history was otherwise unremarkable. Gardner syndrome was ruled out by excluding other associated clinical abnormalities and by family history. The clinical and radiological features of the patients' osteomas were different from those of Albright hereditary osteodystrophy, fibrodysplasia ossificans progressiva, progressive osseous heteroplasia and familial ectopic ossification. To the author's knowledge this is the first case of the familial presentation of osteomas.
Ruggieri
M
M
Division of Paediatric Neurology, University of Catania, Italy.
Pavone
V
V
Polizzi
A
A
Smilari
P
P
Magro
G
G
Merino
M
M
Duray
P H
PH
D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D010016:Osteoma / Q000175:diagnosis / Q000235:genetics*; D010294:Parietal Bone; D012888:Skull Neoplasms / Q000175:diagnosis / Q000235:genetics*