title: Sense of coherence--a protective factor for depression in rheumatoid arthritis.
abstract: OBJECTIVE
  A stress-vulnerability model of depression was investigated in patients with rheumatoid arthritis (RA). Antonovsky's Sense of Coherence (SOC) was examined as a factor protecting against depression.
  
  
  METHODS
  Relationships between sociodemographic factors, disease activity, functional impairment, pain, depression, and SOC were assessed using multivariate methods in a cross sectional sample of 89 consecutive outpatients with RA.
  
  
  RESULTS
  Increased prevalence of depression was associated with low SOC and high self-rated pain levels, but not with other factors assessed. By multiple regression analysis, independent contributions to depression were observed for SOC (23% of variance) and for pain (24% of variance), but not functional impairment or disease activity.
  
  
  CONCLUSIONS
  Comprehensive models of adjustment in RA need to include protective factors such as SOC, in addition to pain and other pathological variables. SOC may be helpful in identifying individuals with RA who are particularly vulnerable to depression, who may be helped by focused psychological interventions such as cognitive therapy.
authors.affiliation: Department of Psychiatry, Imperial College School of Medicine, West Middlesex University Hospital, London, UK.
authors.forename: S
authors.initials: S
authors.lastname: Büchi
authors.forename: T
authors.initials: T
authors.lastname: Sensky
authors.forename: S
authors.initials: S
authors.lastname: Allard
authors.forename: T
authors.initials: T
authors.lastname: Stoll
authors.forename: U
authors.initials: U
authors.lastname: Schnyder
authors.forename: R
authors.initials: R
authors.lastname: Klaghofer
authors.forename: C
authors.initials: C
authors.lastname: Buddeberg
mesh_terms: D000223:Adaptation, Psychological; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000523:psychology*; D003863:Depression / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010146:Pain / Q000209:etiology; D010147:Pain Measurement; D012044:Regression Analysis