title: Inflammatory nevus comedonicus in children.
abstract: More than 100 years has passed since the first report of a nevus comedonicus. The earliest reports emphasized the inflammatory aspect of the nevus comedonicus as being the most significant problem. In the past 30 years, publications have ignored the inflammatory aspect of nevus comedonicus while emphasizing a variety of associated malformations. In this review, we describe five prepubertal children with prominent and persistent inflammatory changes limited to areas within a nevus comedonicus. In our experience, inflammation can be severe and resistant to treatment. Ultimately, surgical removal of the involved skin was required in two children.
authors.affiliation: Department of Dermatology, University of Colorado Health Sciences Center, Denver, USA.
authors.forename: P E
authors.initials: PE
authors.lastname: Vasiloudes
authors.forename: J G
authors.initials: JG
authors.lastname: Morelli
authors.forename: W L
authors.initials: WL
authors.lastname: Weston
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D019980:Amoxicillin-Potassium Clavulanate Combination / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D002610:Cheek / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005153:Facial Neoplasms / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D009506:Nevus / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D012782:Shoulder / Q000473:pathology; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D013899:Thoracic Neoplasms / Q000188:drug therapy / Q000473:pathology; D014212:Tretinoin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D014212:Tretinoin; D019980:Amoxicillin-Potassium Clavulanate Combination