title: [Systemic and local immunity in patients with diabetic retinopathy].
abstract: Total-systems and local immunity parameters were assessed in the lacrimal fluid of 118 patients with nonproliferative and proliferative diabetic retinopathy (DR). Humoral and cellular immunity characteristics of the total-systems immunity were shifted and local immune homeostasis impaired. The most manifest changes were detected in patients with proliferative DR. The authors hypothesize a possible contribution of local immune disorders to the pathogenesis of DR.
authors.forename: V F
authors.initials: VF
authors.lastname: Ekgardt
authors.forename: L N
authors.initials: LN
authors.lastname: Tarasova
authors.forename: S N
authors.initials: SN
authors.lastname: Teplova
authors.forename: T V
authors.initials: TV
authors.lastname: Alekhina
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000917:Antibody Formation / Q000276:immunology; D001402:B-Lymphocytes / Q000276:immunology; D003176:Complement C3 / Q000276:immunology; D003181:Complement C4 / Q000276:immunology; D003930:Diabetic Retinopathy / Q000276:immunology*; D005260:Female; D006801:Humans; D007111:Immunity, Cellular / Q000276:immunology; D007136:Immunoglobulins / Q000276:immunology; D008297:Male; D008875:Middle Aged; D013601:T-Lymphocytes / Q000276:immunology; D013666:Tears / Q000276:immunology*
chemical_list: D003176:Complement C3; D003181:Complement C4; D007136:Immunoglobulins
vernacular_title: Sistemnyĭ i mestnyĭ immunitet u bol'nykh s diabeticheskoĭ retinopatieĭ.