title: [Analytical confirmation of error in false positive amphetamine immunoassays and results].
abstract: Numerous urine samples were found to be positive when using a new amphetamine immunoassay (AxSYM). Confirmation analysis was carried out in a second laboratory at "reasonable prices" using a simple TLC-method with non specific ninhydrine detection and resulted in many "positive" confirmation findings. The GC/MS analysis clearly indicated the absence of amphetamine derivatives regularly encountered in forensic toxicology. The false-positive immunochemical findings may probably be caused by endogenous substances.
authors.affiliation: Institut für Rechtsmedizin, Universität Giessen.
authors.forename: H
authors.initials: H
authors.lastname: Schütz
authors.forename: F
authors.initials: F
authors.lastname: Erdmann
authors.forename: E S
authors.initials: ES
authors.lastname: Magiera
authors.forename: G
authors.initials: G
authors.lastname: Weiler
mesh_terms: D000661:Amphetamine / Q000652:urine*; D005189:False Positive Reactions; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D007118:Immunoassay / Q000592:standards
chemical_list: D000661:Amphetamine
vernacular_title: Fehlerhafte Bestätigungsanalytik bei falsch-positiven Amphetamin-Immunoassays und ihre Auswirkungen.