title: Frequency of steroid sulfatase deficiency in Hiroshima.
abstract: A retrospective survey was performed between 1983 and 1995 to determine the frequency of steroid sulfatase (STS) deficiency in Hiroshima. Males with ichthyosis were diagnosed enzymatically. During 1979-95 in Hiroshima Prefecture, 275,943 males were born and 28 had STS deficiency. The observed frequency of STS deficiency was 1 per 9855 males. Therefore, STS deficiency is fairly prevalent in Japan.
authors.affiliation: Department of Pediatrics, Hiroshima University School of Medicine, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Sakura
authors.forename: S I
authors.initials: SI
authors.lastname: Nishimura
authors.forename: T
authors.initials: T
authors.lastname: Matsumoto
authors.forename: M
authors.initials: M
authors.lastname: Ohsaki
mesh_terms: D001192:Arylsulfatases / Q000172:deficiency*; D002648:Child; D006801:Humans; D016114:Ichthyosis, X-Linked / Q000201:enzymology / Q000453:epidemiology*; D007223:Infant; D007564:Japan / Q000453:epidemiology; D008297:Male; D015995:Prevalence; D012189:Retrospective Studies; D043266:Steryl-Sulfatase
chemical_list: D001192:Arylsulfatases; D043266:Steryl-Sulfatase