[Comparative efficacy of and tolerance to prestarium and lomir in long-term treatment of hypertensive subjects].
An antihypertensive action and tolerance of prestarium and lomir were studied in 31 and 33 hypertensive patients, respectively. They had hypertension stage I-II and took the drug for 12 months. Monotherapy with prestarium in a dose 8 mg/day and lomir (10 mg/day) given twice a day provides a complete hypotensive effect for a year in 56 and 62% of patients, respectively. Combinations prestarium + ariphon, lomir + anapriline or verapamil increased the above number to 100%. The occurrence of side effects of long-term lomir monotherapy was 4 times higher than due to prestarium therapy (39.4 versus 9.7%, respectively).
Nesterov
Iu I
IuI
Ivanova
I V
IV
Gol'dberg
G A
GA
D000328:Adult; D000368:Aged; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D002121:Calcium Channel Blockers / Q000008:administration & dosage / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D007211:Indoles / Q000008:administration & dosage / Q000627:therapeutic use*; D017275:Isradipine / Q000008:administration & dosage / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D020913:Perindopril; D016896:Treatment Outcome
D000806:Angiotensin-Converting Enzyme Inhibitors; D002121:Calcium Channel Blockers; D007211:Indoles; D020913:Perindopril; D017275:Isradipine
Sravnenie éffektivnosti i perenosimosti prestariuma i lomira pri dlitel'nom lechenii bol'nykh arterial'noĭ gipertenzieĭ.