Neuroborreliosis in county Baranya, Hungary.
The incidence and clinical characteristics of Lyme neuroborreliosis (NB) in a region of high prevalence of tick-bite in Hungary is described. In the county Baranya 66 patients were recorded in a five-year period (1989-93). Fifty-six patients (85%) were in "early", and 10 patients (15%) in "late stage" of NB. The sex distribution was equal. The incidence of NB was 2.9-100,000/year in this region. The incidence of radiculitis/neuritis, meningitis, encephalitis and myelitis in the sample was 56.1%, 19.7%, 18.2% and 6%, respectively. The EEG and evoked potentials showed both central and peripheral neural involvement, EMG and ENG abnormalities were related to the peripheral clinical signs. Non-specific white matter lesions could be found by MRI in 5 patients with central involvement. Cerebrospinal fluid changes were not obligatory but a better indicator of inflammatory process in cases with meningitis and/or encephalitis forms (positivity 75%) than in cases with myelitis and radiculitis (positivity 49%).
Pál
E
E
Department of Neurology, University Medical School of Pécs, Hungary.
Barta
Z
Z
Nagy
F
F
Wágner
M
M
Vécsei
L
L
D000293:Adolescent; D000328:Adult; D000368:Aged; D004594:Electrophysiology; D004675:Encephalitis, Tick-Borne / Q000150:complications / Q000453:epidemiology; D005260:Female; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D008193:Lyme Disease / Q000134:cerebrospinal fluid / Q000453:epidemiology* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012621:Seasons; D014057:Tomography, X-Ray Computed