title: Colicin E5 as a new type of cytotoxin, which cleaves a specific group of tRNAs.
abstract: The C-terminal active domain of colicin E5 has a novel ribonuclease activity which specifically cleaves queuine-containing tRNAs. Colicin E5 is a new type cytotoxin targeting a group of tRNAs.
authors.affiliation: Department of Biotechnology, University of Tokyo, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Masaki
authors.forename: T
authors.initials: T
authors.lastname: Ogawa
authors.forename: K
authors.initials: K
authors.lastname: Tomita
authors.forename: T
authors.initials: T
authors.lastname: Ueda
authors.forename: K
authors.initials: K
authors.lastname: Watanabe
authors.forename: T
authors.initials: T
authors.lastname: Uozumi
mesh_terms: D001665:Binding Sites; D003087:Colicins / Q000737:chemistry / Q000378:metabolism*; D004926:Escherichia coli / Q000378:metabolism; D006868:Hydrolysis; D010446:Peptide Fragments / Q000737:chemistry / Q000378:metabolism; D012329:RNA, Bacterial / Q000378:metabolism; D012343:RNA, Transfer / Q000378:metabolism*; D012270:Ribosomes / Q000378:metabolism; D013379:Substrate Specificity
chemical_list: D003087:Colicins; D010446:Peptide Fragments; D012329:RNA, Bacterial; D012343:RNA, Transfer