title: [Between bench and bedside: examples of clinically oriented basic surgery research].
abstract: Animal experimental studies are an effective modality for testing new therapeutic strategies, provided that the animal model and the study protocol simulate the clinical situation. This is exemplified by various animal experimental studies on the therapy of infectious complications in acute necrotizing pancreatitis that were performed preliminary or supplementary to clinical studies. The results show that basic surgical research with close clinical orientation can be usefully and fruitfully combined with clinical studies and enables the academically active young surgeon to overcome the dualism between laboratory work and clinical practice.
authors.affiliation: Abteilung für Allgemein-, Gefäss- und Thoraxchirurgie, Universitätsklinikum Benjamin Franklin, Freie Universität Berlin.
authors.forename: H G
authors.initials: HG
authors.lastname: Hotz
authors.forename: T
authors.initials: T
authors.lastname: Foitzik
authors.forename: N
authors.initials: N
authors.lastname: Runkel
authors.forename: H J
authors.initials: HJ
authors.lastname: Buhr
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D019283:Pancreatitis, Acute Necrotizing / Q000209:etiology / Q000601:surgery*; D012307:Risk Factors; D013530:Surgical Wound Infection / Q000209:etiology / Q000601:surgery*
vernacular_title: Between Bench and Bedside: Beispiele klinisch orientierter chirurgischer Grundlagenforschung.