Protein engineering and the development of generic biosensors.
Biosensors exploit the remarkable specificity of biomolecular recognition to provide analytical tools that can measure the presence of a single molecular species in a complex mixture. A new strategy is emerging in the development of biosensor technologies: molecular-engineering techniques are being used to adapt the properties of proteins to simple, generic detector instrumentation, rather than adapting instruments to the unique requirements of a natural molecule.
Hellinga
H W
HW
Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA.
Marvin
J S
JS
D001665:Binding Sites; D015374:Biosensing Techniques; D011485:Protein Binding; D015202:Protein Engineering; D011506:Proteins / Q000737:chemistry / Q000378:metabolism*; D015398:Signal Transduction
D011506:Proteins