[Antioxidant enzymes activity of erythrocytes and indicators of blood hemodynamics of normal and hypoxic newborns in their first day of life].
The authors have found direct correlating between the enzymatic activity and the values of the total of circulation blood, erythrocytes, plasma and hematocrit. The highest activity of antioxidant-enzymes and values of hemodynamic was observed by the sixth hour of life of healthy newborns. Influenced by simultaneous effect of asphyxia and intrauterine chronic fetal hypoxia SOD, catalase, glucose-6-phosphate dehydrogenase activities in erythrocytes remain low during the first 24 hours of life. These newborns proved to have lower values of hemodynamics. The state of the antioxidant enzyme and hemodynamics at the moment of birth is discussed.
Dubinina
E E
EE
Pediatric Medical Academy, St. Petersbourg, Russia.
Talanova
I Iu
IIu
Burmistrov
S O
SO
Shabalov
N P
NP
D001238:Asphyxia Neonatorum / Q000097:blood*; D002374:Catalase / Q000097:blood*; D004796:Clinical Enzyme Tests; D004912:Erythrocytes / Q000201:enzymology*; D005311:Fetal Hypoxia / Q000097:blood*; D005954:Glucosephosphate Dehydrogenase / Q000097:blood*; D006400:Hematocrit; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D007231:Infant, Newborn; D010101:Oxygen Consumption / Q000502:physiology; D013482:Superoxide Dismutase / Q000097:blood*
D005954:Glucosephosphate Dehydrogenase; D002374:Catalase; D013482:Superoxide Dismutase
Fermenty antioksidantnoĭ sistemy éritrotsitov i nekotorye pokazateli gemodinamiki krovi v pervye sutki zhizni novorozhdennykh deteĭ v norme i pri gipoksicheskikh sostoianiiakh.