title: Timing algorithm for bolus chase MR digital subtraction angiography.
abstract: To acquire multiple longitudinal locations in the lower extremity after a single contrast injection, appropriate table translation and contrast injection are required. An approximate model based on constant bolus velocity was developed to describe the space-time course of a contrast bolus in the lower extremity. This model was verified in dynamic MR angiograms acquired in a group of patients using time-resolved 2D MR digital subtraction angiography (MRDSA). From this contrast bolus passage model, a timing algorithm for table translation and contrast injection was developed for bolus chase MRDSA, subsequently validated in bolus chase 2D MRDSA experiments. All targeted major peripheral arteries were well depicted in bolus chase 2D MRDSA using this timing algorithm and a single 15-ml contrast dose.
authors.affiliation: Department of Radiology, Cornell University Medical College, New York, NY 10021, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.forename: H M
authors.initials: HM
authors.lastname: Lee
authors.forename: R
authors.initials: R
authors.lastname: Avakian
authors.forename: P A
authors.initials: PA
authors.lastname: Winchester
authors.forename: N M
authors.initials: NM
authors.lastname: Khilnani
authors.forename: D
authors.initials: D
authors.lastname: Trost
mesh_terms: D000328:Adult; D000465:Algorithms; D003287:Contrast Media; D005260:Female; D019786:Gadolinium DTPA; D006801:Humans; D007275:Injections, Intravenous; D007866:Leg / Q000098:blood supply; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D016491:Peripheral Vascular Diseases / Q000175:diagnosis; D013382:Subtraction Technique; D013997:Time Factors
chemical_list: D003287:Contrast Media; C064925:gadodiamide; D019786:Gadolinium DTPA