title: [Eye involvement in Chagas disease (American trypanosomiasis). 1996/1997 studies in Paraguay].
abstract: BACKGROUND
  Last year's pilot study, which examined for the first time a representative group of patients with Chagas disease, showed that in this parasitosis changes in the ocular fundus can be expected in the form of defects of the retinal pigment epithelium. Examination of more patients in this study should give further information about the character and extent of the alterations found.
  
  
  METHODS
  After serological confirmation of the disease, we performed an ophthalmological examination of the anterior and posterior segments.
  
  
  RESULTS
  In 21 out of 23 patients the fundus was unobtrusive; 1 patient showed fibrae medullares and 1 patient clear pigment dispersion on the posterior pole. Together with the pilot study, a total of 102 chagasic patients were examined. In 8 patients (7.8%) defects of the retinal pigment epithelium were found, which did not cause any significant loss of vision.
  
  
  CONCLUSIONS
  We presume that the described defects are a matter of rare and harmless postinflammatory or immunological changes in the American type of trypanosomiasis.
authors.affiliation: Augenklinik, Klinikum Innenstadt der LMU München.
authors.forename: S J
authors.initials: SJ
authors.lastname: Fröhlich
authors.forename: H
authors.initials: H
authors.lastname: Miño de Kaspar
authors.forename: R
authors.initials: R
authors.lastname: Perán
authors.forename: A
authors.initials: A
authors.lastname: Rojas de Arias
authors.forename: N
authors.initials: N
authors.lastname: Sanchez Insfran
authors.forename: R
authors.initials: R
authors.lastname: Moreno Azorero
authors.forename: V
authors.initials: V
authors.lastname: Klauss
mesh_terms: D000328:Adult; D014355:Chagas Disease / Q000175:diagnosis*; D002648:Child; D005260:Female; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D010239:Paraguay; D010857:Pigment Epithelium of Eye / Q000473:pathology; D010865:Pilot Projects; D012164:Retinal Diseases / Q000175:diagnosis*; D014792:Visual Acuity / Q000502:physiology
vernacular_title: Augenbeteiligung bei Chagas-Krankheit (Amerikanische Trypanosomiasis). Untersuchungen in Paraguay 1996/1997.