title: Post-kala-azar dermal leishmaniasis with mucosal involvement in a kidney transplant recipient: treatment with liposomal amphotericin B.
abstract: Post-kala-azar dermal leishmaniasis (PKDL) is a rare clinical variant of cutaneous leishmaniasis. It is very common in the Indian subcontinent and less frequent in East Africa, but exceptional in the American and European continents. We have observed a case of PKDL in a renal transplant recipient. No systemic symptoms were present. The patient was treated with liposomal amphotericin B. We emphasize the unusual aspects of this case: the appearance of PKDL in Europe, its relationship with immunosuppression, the severe mucosal involvement and the excellent response to liposomal amphotericin B, a newly described treatment for the disease.
authors.affiliation: Department of Dermatology, Hospital Puerta de Hierro, Madrid, Spain.
authors.forename: G
authors.initials: G
authors.lastname: Roustan
authors.forename: J A
authors.initials: JA
authors.lastname: Jiménez
authors.forename: B
authors.initials: B
authors.lastname: Gutiérrez-Solar
authors.forename: J L
authors.initials: JL
authors.lastname: Gallego
authors.forename: J
authors.initials: J
authors.lastname: Alvar
authors.forename: M
authors.initials: M
authors.lastname: Patrón
mesh_terms: D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D004337:Drug Carriers; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation; D016773:Leishmaniasis, Cutaneous / Q000188:drug therapy / Q000209:etiology*; D007898:Leishmaniasis, Visceral / Q000150:complications*; D008081:Liposomes; D008297:Male
chemical_list: D000900:Anti-Bacterial Agents; D004337:Drug Carriers; D008081:Liposomes; D000666:Amphotericin B