title: Relationship between free-living daily physical activity and ambulatory measures in older claudicants.
abstract: The purpose of this study was to determine the relationship between free-living daily physical activity and ambulatory measurements in peripheral arterial occlusive disease (PAOD) patients with intermittent claudication. Thirty-four older, nonsmoking PAOD patients with intermittent claudication (age=69.0 +/- 6.0 years, ankle/brachial index [ABI] =0.63 +/- 0.18) were recruited from the Vascular Clinic at the Baltimore Veterans Affairs Medical Center and from radio and newspaper advertisements. Energy expenditure of physical activity (EEPA) was determined by using doubly labeled water and indirect calorimetry techniques. Patients were also characterized on claudication distances and peak oxygen uptake during a graded treadmill test, 6-minute walking distance, weight, body mass index, and percent body fat. The claudication patients were sedentary, as EEPA was 362 +/- 266 kcal/day. EEPA was related to the 6-minute walk distance (369 +/- 68 meters; r=0.629, P<0.001), to the number of steps taken during 6 minutes (605 +/- 99 steps; r=0.485, P=0.008), to the treadmill distance to maximal claudication (313 +/- 131 meters; r=0.470, P=0.010), and to the time to relief of pain (6:21 +/- 3:57 min:sec; r=-0.417, P=0.017). None of the other ambulatory and body composition measurements were correlated with EEPA. In conclusion, a reduction in free-living daily physical activity was associated with a decrease in ambulatory ability and with more severe intermittent claudication in older PAOD patients.
authors.affiliation: Claude D. Pepper Older Americans Independence Center, Department of Medicine, University of Maryland, Baltimore, USA.
authors.forename: A W
authors.initials: AW
authors.lastname: Gardner
authors.forename: C J
authors.initials: CJ
authors.lastname: Womack
authors.forename: D J
authors.initials: DJ
authors.lastname: Sieminski
authors.forename: P S
authors.initials: PS
authors.lastname: Montgomery
authors.forename: L A
authors.initials: LA
authors.lastname: Killewich
authors.forename: T
authors.initials: T
authors.lastname: Fonong
mesh_terms: D000203:Activities of Daily Living; D000273:Adipose Tissue / Q000473:pathology; D000368:Aged; D000369:Aged, 80 and over; D000842:Ankle / Q000098:blood supply; D001157:Arterial Occlusive Diseases / Q000503:physiopathology; D001794:Blood Pressure / Q000502:physiology; D001823:Body Composition / Q000502:physiology; D015992:Body Mass Index; D001835:Body Weight; D001916:Brachial Artery / Q000502:physiology; D002151:Calorimetry; D004734:Energy Metabolism / Q000502:physiology; D005080:Exercise Test; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D007383:Intermittent Claudication / Q000503:physiopathology*; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology; D010101:Oxygen Consumption / Q000502:physiology; D010146:Pain / Q000503:physiopathology; D016491:Peripheral Vascular Diseases / Q000503:physiopathology; D013997:Time Factors; D016138:Walking / Q000502:physiology*