title: Molecular scanning of the insulin receptor substrate 1 gene in subjects with severe insulin resistance: detection and functional analysis of a naturally occurring mutation in a YMXM motif.
authors.affiliation: Department of Medicine, University of Cambridge, Addenbrooke's Hospital, UK. jpw27@cus.cam.ac.uk
authors.forename: J P
authors.initials: JP
authors.lastname: Whitehead
authors.forename: P
authors.initials: P
authors.lastname: Humphreys
authors.forename: A
authors.initials: A
authors.lastname: Krook
authors.forename: R
authors.initials: R
authors.lastname: Jackson
authors.forename: A
authors.initials: A
authors.lastname: Hayward
authors.forename: H
authors.initials: H
authors.lastname: Lewis
authors.forename: K
authors.initials: K
authors.lastname: Siddle
authors.forename: S
authors.initials: S
authors.lastname: O'Rahilly
mesh_terms: D000293:Adolescent; D000595:Amino Acid Sequence; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics*; D005260:Female; D006801:Humans; D055504:Insulin Receptor Substrate Proteins; D007333:Insulin Resistance / Q000235:genetics*; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D010750:Phosphoproteins / Q000235:genetics*; D011972:Receptor, Insulin
chemical_list: C526292:IRS1 protein, human; D055504:Insulin Receptor Substrate Proteins; D010750:Phosphoproteins; D011972:Receptor, Insulin