title: Distraction osteogenesis: application to dentofacial orthopedics.
abstract: Distraction osteogenesis is a surgical-orthopedic method for lengthening bone by separating or distracting a fracture callus. This technique has a long history in limb lengthening and has recently been used to lengthen mandibles and maxillae in human patients. Distraction osteogenesis represents a powerful method of producing unlimited quantities of living bone which can be formed along any plane of space. Because this method uses local host tissue, it offers many advantages over bone grafting. In the author's experience, large (10-22 mm) antero-posterior and vertical corrections of mandibles can be achieved using this technique. The purpose of this article is to review its biological basis and discuss recent clinical applications. This article reviews the history, theory, current management, and limitations of distraction osteogenesis in treating craniofacial anomalies.
authors.affiliation: Center for Craniofacial Molecular Biology, University of Southern California, Los Angeles 90033, USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Yen
mesh_terms: D002508:Cephalometry; D019465:Craniofacial Abnormalities / Q000175:diagnosis / Q000601:surgery*; D005146:Facial Asymmetry / Q000175:diagnosis / Q000601:surgery*; D005544:Forecasting; D006801:Humans; D008334:Mandible / Q000601:surgery; D008437:Maxilla / Q000601:surgery; D019857:Osteogenesis, Distraction / Q000295:instrumentation / Q000379:methods* / Q000639:trends