Ocular melanomas and melanocytic lesions of the eye.
This article describes several melanocytic lesions of the eye. Benign and malignant lesions will be discussed as well as a review of the dysplastic nevus syndrome and its proposed association with ocular melanoma. Ocular melanomas arise from the same embryologically derived melanocytes as their cutaneous counterparts. However, ocular and cutaneous melanomas differ in many respects. The diagnosis and management of these ocular tumors rely heavily on the ophthalmologist. However, knowledge of melanocytic lesions will aid the dermatologist in detection and in proper referral of these patients.
Grin
J M
JM
Department of Dermatology and Dermatopathology, University of Connecticut School of Medicine, Farmington 06032, USA.
Grant-Kels
J M
JM
Grin
C M
CM
Berke
A
A
Kels
B D
BD
D003230:Conjunctival Neoplasms / Q000175:diagnosis / Q000473:pathology; D003880:Dermatology; D004416:Dysplastic Nevus Syndrome / Q000175:diagnosis / Q000473:pathology; D005123:Eye / Q000033:anatomy & histology; D005128:Eye Diseases / Q000175:diagnosis* / Q000473:pathology; D005134:Eye Neoplasms / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008544:Melanocytes / Q000473:pathology; D008545:Melanoma / Q000175:diagnosis* / Q000473:pathology; D008548:Melanosis / Q000175:diagnosis / Q000473:pathology; D009506:Nevus / Q000175:diagnosis / Q000473:pathology; D009507:Nevus of Ota / Q000175:diagnosis / Q000473:pathology; D009885:Ophthalmology; D010859:Pigmentation Disorders / Q000175:diagnosis* / Q000473:pathology; D012017:Referral and Consultation; D015422:Scleral Diseases / Q000175:diagnosis / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology; D014604:Uveal Neoplasms / Q000175:diagnosis / Q000473:pathology