title: [Phenotypic analysis in colorectal carcinoma: an international interdisciplinary project].
abstract: An European research network grouping surgeons, pathologists, biochemists and molecular biologists is presented. The aim of this network is to define new diagnostic, prognostic and therapeutic markers at protein and RNA levels in colorectal cancer. The methodology is based on specific sample preparation techniques, allowing the isolation of pure epithelial cells, and on differential-display techniques, such as two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) and reverse arbitrarily-primed polymerase chain reaction (RAP-PCR).
authors.affiliation: Chirurgische Klinik, Universität Erlangen.
authors.forename: M A
authors.initials: MA
authors.lastname: Reymond
authors.forename: J C
authors.initials: JC
authors.lastname: Sanchez
authors.forename: C
authors.initials: C
authors.lastname: Schneider
authors.forename: P
authors.initials: P
authors.lastname: Rohwer
authors.forename: S
authors.initials: S
authors.lastname: Tortola
authors.forename: M A
authors.initials: MA
authors.lastname: Peinado
authors.forename: D
authors.initials: D
authors.lastname: Hochstrasser
authors.forename: T
authors.initials: T
authors.lastname: Kirchner
authors.forename: W
authors.initials: W
authors.lastname: Hohenberger
authors.forename: F
authors.initials: F
authors.lastname: Köckerling
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics; D015179:Colorectal Neoplasms / Q000235:genetics* / Q000473:pathology; D004848:Epithelium / Q000473:pathology; D015972:Gene Expression Regulation, Neoplastic / Q000502:physiology; D006801:Humans; D007391:International Cooperation; D007413:Intestinal Mucosa / Q000473:pathology; D009363:Neoplasm Proteins / Q000235:genetics; D010348:Patient Care Team; D010641:Phenotype; D011379:Prognosis; D012334:RNA, Neoplasm / Q000235:genetics
chemical_list: D014408:Biomarkers, Tumor; D009363:Neoplasm Proteins; D012334:RNA, Neoplasm
vernacular_title: Phänotypische Analyse beim kolorektalen Karzinom: ein internationales interdisziplinäres Projekt.