Structure-activity relationship in Ftorafur (Tegafur) and related 5-FU prodrugs.
Zhuk
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Latvian Institute of Organic Synthesis, Riga, Latvia.
D000818:Animals; D000964:Antimetabolites, Antineoplastic / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D005472:Fluorouracil / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D006801:Humans; D007202:Indicators and Reagents; D007939:Leukemia L1210 / Q000188:drug therapy; D051379:Mice; D008815:Mice, Inbred Strains; D015394:Molecular Structure; D011355:Prodrugs / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use; D012709:Serum Albumin / Q000378:metabolism; D013329:Structure-Activity Relationship; D005641:Tegafur / Q000138:chemical synthesis / Q000737:chemistry* / Q000627:therapeutic use
D000964:Antimetabolites, Antineoplastic; D007202:Indicators and Reagents; D011355:Prodrugs; D012709:Serum Albumin; D005641:Tegafur; D005472:Fluorouracil