title: Preparation of thietane derivatives from 2-(3-hydroxyalkylthio)benzoxazoles and their conversion into thietane nucleosides.
abstract: Thietanes were prepared by the reaction of 2-(3-hydroxyalkylthio)benzoxazoles with KH. 3,3-Dibenzylthietane was oxidized by mCPBA to give 3,3-dibenzylthietane-1-oxide, which was converted into thietane nucleosides (Pummerer-type-reaction).
authors.affiliation: Department of Chemistry, College of Science and Engineering, Aoyama Gakuin University, Tokyo, Japan.
authors.forename: D
authors.initials: D
authors.lastname: Ikemizu
authors.forename: A
authors.initials: A
authors.lastname: Matsuyama
authors.forename: T
authors.initials: T
authors.lastname: Endo
authors.forename: O
authors.initials: O
authors.lastname: Mitsunobu
mesh_terms: D001583:Benzoxazoles; D007202:Indicators and Reagents; D013440:Sulfides; D013872:Thionucleosides / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D001583:Benzoxazoles; D007202:Indicators and Reagents; D013440:Sulfides; D013872:Thionucleosides