title: [Neurobiology of erectile dysfunction in multiple sclerosis].
abstract: OBJECTIVE
  To analyze the neurological alterations responsible for impotence in multiple sclerosis.
  
  
  METHODS
  We conducted a pharmacologic erection test and a neuroandrologic profile study in 11 patients with multiple sclerosis and impotence. This study consisted in: bulbocavernosus EMG, S2-S4 evoked potentials, somatosensory potentials of pudendal nerve, electromyography of cavernous smooth muscle (SPACE), sympathetic skin response (SSR) and cystometry.
  
  
  RESULTS
  The most frequent neurological lesion was complete suprasacral (7 cases; 64%) and parasympathetic (7 cases; 64%) lesions. The parasympathetic lesions were of the upper motor neuron type in 6 of the 7 cases (86%). Peripheral autonomic [sympathetic in 2 cases (18%); parasympathetic in 1 case (9%)] and pudendal lesions (3 cases; 27%) were also observed.
  
  
  CONCLUSIONS
  The main cause of impotence in multiple sclerosis could be ascribed to a suprasacral lesion. Some cases also present peripheral autonomic lesions.
authors.affiliation: Servicio de Urología, Hospital Universitario San Carlos, Universidad Complutense, Madrid, España.
authors.forename: J
authors.initials: J
authors.lastname: Salinas Casado
authors.forename: M
authors.initials: M
authors.lastname: Vírseda Chamorro
authors.forename: R
authors.initials: R
authors.lastname: Samblás García
authors.forename: M
authors.initials: M
authors.lastname: Esteban Fuertes
authors.forename: J M
authors.initials: JM
authors.lastname: Aristizábal Agudelo
authors.forename: J A
authors.initials: JA
authors.lastname: Delgado Martín
authors.forename: J
authors.initials: J
authors.lastname: Blázquez Izquierdo
authors.forename: L
authors.initials: L
authors.lastname: Resel Estévez
mesh_terms: D000328:Adult; D007172:Erectile Dysfunction / Q000209:etiology*; D006801:Humans; D008297:Male; D009103:Multiple Sclerosis / Q000150:complications*; D010275:Parasympathetic Nervous System; D010413:Penis / Q000294:innervation*; D010523:Peripheral Nervous System Diseases / Q000150:complications; D013564:Sympathetic Nervous System
vernacular_title: Neurobiología de la disfunción eréctil en la esclerosis múltiple.