title: Portal vein reconstruction with conventional polytetrafluoroethylene grafts: an experimental study in dogs.
abstract: The purpose of this study was to examine the short- and long-term performance of conventional polytetrafluoroethylene (PTFE) grafts for portal vein reconstruction. The grafts were placed as a portal vein replacement in 11 mongrel dogs. At 1 month and 6 months, the grafts were then retrieved and examined for patency, while also undergoing a pathological analysis. During the observation period (at 55 days), one dog died of an unknown cause with a patent graft. The patency rates of the other 10 grafts were 83% (5/6) at 1 month and 100% (4/4) at 6 months. However, the neointima formation was incomplete even 6 months after implantation. In conclusion, although conventional PTFE grafts may be used as a synthetic alternative to autogenous vein grafts, every effort should be made to use autogenous vein grafts before considering conventional PTFE grafts.
authors.affiliation: Second Department of Surgery, Hokkaido University School of Medicine, Sapporo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Nishibe
authors.forename: H
authors.initials: H
authors.lastname: Manase
authors.forename: K
authors.initials: K
authors.lastname: Miyazaki
authors.forename: H
authors.initials: H
authors.lastname: Ohkashiwa
authors.forename: Y
authors.initials: Y
authors.lastname: Satoh
authors.forename: S
authors.initials: S
authors.lastname: Watanabe
authors.forename: T
authors.initials: T
authors.lastname: Takahashi
authors.forename: H
authors.initials: H
authors.lastname: Katoh
authors.forename: Y
authors.initials: Y
authors.lastname: Okuda
authors.forename: T
authors.initials: T
authors.lastname: Tanabe
mesh_terms: D000818:Animals; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods; D004285:Dogs; D011138:Polytetrafluoroethylene; D011169:Portal Vein / Q000601:surgery*; D011183:Postoperative Complications; D019651:Plastic Surgery Procedures / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D011138:Polytetrafluoroethylene