title: Epileptic skew deviation.
abstract: We describe a 43-year-old neurologically intact patient who reported episodes of diplopia and oscillopsia associated with a right-beating nystagmus and a skew deviation. These symptoms and signs were related to a left posterior epileptic EEG discharge. We suggest that these ocular motor signs derived from an ictal activation of the vestibular cortex, which in turn activated descending projections to the vestibular nuclei, leading to both a dynamic (right-beating nystagmus) and a static (skew deviation) vestibular imbalance.
authors.affiliation: Epilepsy Centre, Neurological Institute C. Mondino Foundation, Pavia, Italy.
authors.forename: C A
authors.initials: CA
authors.lastname: Galimberti
authors.forename: M
authors.initials: M
authors.lastname: Versino
authors.forename: I
authors.initials: I
authors.lastname: Sartori
authors.forename: R
authors.initials: R
authors.lastname: Manni
authors.forename: A
authors.initials: A
authors.lastname: Martelli
authors.forename: A
authors.initials: A
authors.lastname: Tartara
mesh_terms: D000328:Adult; D004172:Diplopia / Q000209:etiology* / Q000503:physiopathology; D004569:Electroencephalography; D004828:Epilepsies, Partial / Q000150:complications* / Q000503:physiopathology; D005133:Eye Movements / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009759:Nystagmus, Pathologic / Q000209:etiology* / Q000503:physiopathology