Molecular scanning of the insulin receptor substrate 1 gene in subjects with severe insulin resistance: detection and functional analysis of a naturally occurring mutation in a YMXM motif.
Whitehead
J P
JP
Department of Medicine, University of Cambridge, Addenbrooke's Hospital, UK. jpw27@cus.cam.ac.uk
Humphreys
P
P
Krook
A
A
Jackson
R
R
Hayward
A
A
Lewis
H
H
Siddle
K
K
O'Rahilly
S
S
D000293:Adolescent; D000595:Amino Acid Sequence; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics*; D005260:Female; D006801:Humans; D055504:Insulin Receptor Substrate Proteins; D007333:Insulin Resistance / Q000235:genetics*; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D010750:Phosphoproteins / Q000235:genetics*; D011972:Receptor, Insulin
C526292:IRS1 protein, human; D055504:Insulin Receptor Substrate Proteins; D010750:Phosphoproteins; D011972:Receptor, Insulin