title: Migraine with visual aura and photosensitive epileptic seizures.
abstract: A relationship between epilepsy and migraine has long been postulated, but the nature of this interaction is still debated. We observed this association in a 23-year old man with a history of migraine with visual aura who had seizures at age 15 years while watching television. Waking EEG was normal, but sleep recordings demonstrated posterior spike-waves during sleep. During intermittent photic stimulation (IPS), a photoparoxysmal response occurred, maximum in occipital areas. Brain magnetic resonance imaging scan was normal. Seizures did not recur after 4-year treatment with valproate. He is currently seizure-free, but continues to have rare migraine with visual aura. The role of spreading depression or of a putative dopaminergic failure in occipital cortex is discussed.
authors.affiliation: Centre Saint-Paul, Marseille, France.
authors.forename: A
authors.initials: A
authors.lastname: Donnet
authors.forename: F
authors.initials: F
authors.lastname: Bartolomei
mesh_terms: D000328:Adult; D015897:Comorbidity; D013181:Cortical Spreading Depression / Q000502:physiology; D004298:Dopamine / Q000502:physiology; D004569:Electroencephalography / Q000706:statistics & numerical data; D004827:Epilepsy / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology*; D009778:Occipital Lobe / Q000503:physiopathology; D010775:Photic Stimulation; D012607:Scotoma / Q000175:diagnosis / Q000453:epidemiology; D014635:Valproic Acid / Q000627:therapeutic use
chemical_list: D014635:Valproic Acid; D004298:Dopamine