Effect of topical miconazole in plaque psoriasis.
The aim of this study was the assessment of efficacy and tolerance of topical miconazole in plaque psoriasis. 9 patients aged 23-63 years with diagnosis of plaque psoriasis were enrolled. 2% miconazole cream was applied twice daily from 7 to 12 weeks (under occlusive dressing to obtain optimal penetration of the drug) in the plaque with a minimum diameter of 5 cm. In most patients clinical improvement of the topical miconazole treatment was observed.
Niczyporuk
W
W
Department of Dermatology, Venerology Medical Academy of Białystok.
Krajewska-Kułak
E
E
D000279:Administration, Cutaneous; D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D003879:Dermatologic Agents / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D006801:Humans; D008825:Miconazole / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000627:therapeutic use*; D008875:Middle Aged; D009779:Occlusive Dressings; D009824:Ointments; D010865:Pilot Projects; D011565:Psoriasis / Q000188:drug therapy*; D012869:Skin Absorption
D000935:Antifungal Agents; D003879:Dermatologic Agents; D009824:Ointments; D008825:Miconazole