title: Risk Score Estimation: a new method to determine optimal timing of aneurysm clipping for improved management outcome.
abstract: The outcome of 703 patients who underwent surgery following aneurysmal subarachnoid hemorrhage were analyzed with regards to age, associated medical conditions, vasospasm and clinical status at the time of operation. Patients with Hunt and Hess grade I, II, and III had a 96%, 90% and 93% favorable (good and fair) outcome respectively. In contrast only 58% of patients with grade IV had the same result. The outcome was unfavorable in 13% of the patients who were older than 60 years of age and only in 9% of the patients between 30-59 years of age. All the patients younger than 30 years old had a good outcome. Associated medical condition increased the incidences of poor outcome (7% vs. 12%). Patients harboring vertebro basilar aneurysms had a poorer outcome, as opposed to those with aneurysms located in the anterior circulation (20% vs. 8%). The presence of angiographic vasospasm alone did not influence outcome. A proposed point value was given for each of the adverse factors and from this the optimal surgical time was determined for each individual patient. This concept of Risk Score Estimation approach may improve the management outcome of patients with ruptured intracranial aneurysms.
authors.affiliation: Department of Neuroscience and Epilepsy Center, King-Drew Medical Center, Los Angeles, CA 90059, USA.
authors.forename: D H
authors.initials: DH
authors.lastname: Duong
authors.forename: V R
authors.initials: VR
authors.lastname: Kolluri
authors.forename: P J
authors.initials: PJ
authors.lastname: Spittaler
authors.forename: R P
authors.initials: RP
authors.lastname: Sengupta
mesh_terms: D000328:Adult; D017677:Age Distribution; D017542:Aneurysm, Ruptured / Q000401:mortality* / Q000601:surgery*; D001161:Arteriosclerosis / Q000453:epidemiology; D002543:Cerebral Hemorrhage / Q000401:mortality / Q000601:surgery; D002560:Cerebrovascular Circulation; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D002532:Intracranial Aneurysm / Q000401:mortality* / Q000601:surgery*; D016015:Logistic Models; D008171:Lung Diseases / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D018570:Risk Assessment; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D014661:Vasoconstriction