title: The role of esophagectomy in the management of esophageal perforations.
abstract: BACKGROUND
  Despite the many advancements made in thoracic surgery, the management of patients with esophageal perforation remains problematic and controversial.
  
  
  METHODS
  Between 1985 and 1995, 27 esophagectomies were performed for perforation of the thoracic esophagus. A retrospective review of the records of these patients was carried out, and a scoring scale developed by Elebute and Stoner to grade the severity of sepsis was applied.
  
  
  RESULTS
  Among the 27 patients undergoing esophagectomy for a perforation, the interval between rupture and esophagectomy was less than 24 hours in only 11 patients (40.7%). Postoperative surgical complications occurred in 4 patients (14.8%) and nonsurgical complications, in 7 (25.9%). The hospital mortality rate was 3.7% (1/27). In 14 patients, primary reconstruction was performed in the bed of the excised esophagus. There were no anastomotic leaks in this subgroup. This suggests that an anastomosis between viable, well-vascularized tissues is more important for successful healing than avoidance of some degree of contamination of the adjacent mediastinum. On follow-up, which averages 41 months, 73% of patients (16/22) have neither symptoms nor complaints.
  
  
  CONCLUSIONS
  Esophageal resection definitively eliminates the source of intrathoracic sepsis, the perforation, and the affected esophagus. Reconstruction carried out in one stage does not increase operative morbidity. Esophageal resection and reconstruction is a valid approach even in cases of spontaneous perforation in which the diagnosis is markedly delayed.
authors.affiliation: Department of Surgery, Postgraduate Medical University, Budapest, Hungary.
authors.forename: A
authors.initials: A
authors.lastname: Altorjay
authors.forename: J
authors.initials: J
authors.lastname: Kiss
authors.forename: A
authors.initials: A
authors.lastname: Vörös
authors.forename: E
authors.initials: E
authors.lastname: Szirányi
mesh_terms: D000328:Adult; D000368:Aged; D000714:Anastomosis, Surgical / Q000379:methods; D004935:Esophageal Diseases / Q000209:etiology / Q000601:surgery; D004939:Esophageal Perforation / Q000601:surgery*; D016629:Esophagectomy / Q000009:adverse effects / Q000379:methods; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008482:Mediastinum / Q000382:microbiology; D008875:Middle Aged; D011183:Postoperative Complications; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012422:Rupture, Spontaneous; D018805:Sepsis / Q000209:etiology; D015996:Survival Rate; D013896:Thoracic Diseases / Q000382:microbiology; D013997:Time Factors; D014945:Wound Healing