A, B & H isoantigens in cervical lesions.
Expression of A, B and H isoantigens in cervical mucosa was demonstrated by specific red cell adherence test in 92 cervical lesions (40 chronic cervicitis, 12 dysplasia and 40 carcinoma cervix). Eighty percent cases of chronic cervicitis showed a moderate reaction. On the contrary, in carcinoma cervix, 75% cases were found to be SRCA negative. In dysplasia, the intensity of red blood cell adherence was found to be directly related to the degree of cellular differentiation. Study of A, B and H isoantigens might help in deciding the prognosis of dysplasia and/or early detection of malignancy.
Bisht
D
D
Department of Pathology, Moti Lal Nehru Medical College, Allahabad.
Misra
V
V
Gupta
S C
SC
Mehrotra
R
R
Garg
S
S
D000017:ABO Blood-Group System / Q000032:analysis*; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000276:immunology / Q000473:pathology; D002448:Cell Adhesion; D002584:Cervix Uteri / Q000276:immunology / Q000473:pathology; D004912:Erythrocytes / Q000502:physiology; D005260:Female; D006801:Humans; D011379:Prognosis; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D002575:Uterine Cervicitis / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology
D000017:ABO Blood-Group System