title: Prolonged response of multicentric reticulohistiocytosis to low dose methotrexate.
abstract: We describe a case of multicentric reticulohistiocytosis complicated by central retinal vein thrombosis and trigeminal neuropathy. A variety of treatment modalities were tried in this patient. Both skin disease and arthritis responded to low dose methotrexate over 8 years of followup. Graduated compression gloves produced an excellent cosmetic improvement in the disfiguring skin lesions.
authors.affiliation: Walter and Eliza Hall Institute of Medical Research, Department of Occupational Therapy, The Royal Melbourne Hospital, Victoria, Australia.
authors.forename: J L
authors.initials: JL
authors.lastname: Rentsch
authors.forename: E M
authors.initials: EM
authors.lastname: Martin
authors.forename: L C
authors.initials: LC
authors.lastname: Harrison
authors.forename: I P
authors.initials: IP
authors.lastname: Wicks
mesh_terms: D000328:Adult; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D005260:Female; D015616:Histiocytosis, Non-Langerhans-Cell / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D008727:Methotrexate / Q000627:therapeutic use*; D012871:Skin Diseases / Q000188:drug therapy / Q000473:pathology
chemical_list: D018501:Antirheumatic Agents; D008727:Methotrexate