Acute myeloid leukemia with a novel (7;11)(q36;q13) translocation.
A 79-year-old female presented with acute myeloblastic leukemia without maturation. Cytogenetic studies showed a previously undescribed abnormality of t(7;11)(q36;q13). The significance of the involvement of 11q13 in the pathogenesis of myeloid leukemia is discussed.
Wong
K F
KF
Department of Pathology, Queen Elizabeth Hospital, Hong Kong, China.
Chu
Y C
YC
D000368:Aged; D002880:Chromosomes, Human, Pair 11 / Q000235:genetics*; D002897:Chromosomes, Human, Pair 7 / Q000235:genetics*; D005260:Female; D006801:Humans; D007621:Karyotyping; D015470:Leukemia, Myeloid, Acute / Q000235:genetics* / Q000473:pathology; D014178:Translocation, Genetic / Q000235:genetics*