title: Retrograde double-labeling study of retinal ganglion cells from the ipsilateral vLGN and SC in the albino rat.
abstract: Retinal ganglion cells with branches to the ipsilateral ventral lateral geniculate nucleus (vLGN) and superior colliculus (SC) were studied by retrograde fluorescent double-labeling. Double-labeled cells were found in the ventral temporal crescent of the retina, with a few ipsilaterally projecting single-labeled cells scattered in this area. Single-labeled vLGN-projecting cells were found predominantly in the ventral-temporal crescent and to a lesser extent in the temporal and dorsotemporal octant. SC-projecting cells were present predominantly in the ventral-temporal crescent and to a lesser extent in the ventral and ventronasal octant. Our best animal model had 2200 ipsilaterally labeled cells. There were 451 (20.5%) double-labeled vLGN and SC-projecting cells, 561 (25.5%) single-labeled vLGN-projecting cells, and 1186 (53.9%) single-labeled SC-projecting cells.
authors.affiliation: Department of Ophthalmology, New York Medical College, Valhalla 10595, USA. farid-ahmed@nymc.edu
authors.forename: A K
authors.initials: AK
authors.lastname: Farid Ahmed
authors.forename: K
authors.initials: K
authors.lastname: Dong
authors.forename: G F
authors.initials: GF
authors.lastname: Hanna
authors.forename: T
authors.initials: T
authors.lastname: Yamadori
mesh_terms: D000818:Animals; D001370:Axonal Transport; D002452:Cell Count; D003911:Dextrans / Q000378:metabolism; D005260:Female; D005456:Fluorescent Dyes / Q000378:metabolism; D005829:Geniculate Bodies / Q000378:metabolism / Q000502:physiology*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012165:Retinal Ganglion Cells / Q000378:metabolism / Q000502:physiology*; D012235:Rhodamines / Q000378:metabolism; D013266:Stilbamidines; D013477:Superior Colliculi / Q000378:metabolism / Q000502:physiology*
chemical_list: C049774:2-hydroxy-4,4'-diamidinostilbene, methanesulfonate salt; D003911:Dextrans; D005456:Fluorescent Dyes; C067661:Fluoro-Ruby; D012235:Rhodamines; D013266:Stilbamidines