Two marine Agrobacterium producers of sesbanimide antibiotics.
Sesbanimides are cytotoxic compounds, originally isolated in 1983 from seeds of the leguminous plants Sesbania drummondii and Sesbania punicea. In this paper we describe the bacterial production of sesbanimides by two "marine Agrobacterium"; strain PH-103 which produces Sesbanimide-A and strain PH-A034C which produces Sesbanimide-C. The isolation and taxonomy of the producing microorganisms, fermentation and isolation of sesbanimides are reported.
Acebal
C
C
Instituto Biomar, S.A., León, Spain.
Alcazar
R
R
Cañedo
L M
LM
de la Calle
F
F
Rodriguez
P
P
Romero
F
F
Fernandez Puentes
J L
JL
D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification*; D004187:Disaccharides / Q000737:chemistry / Q000302:isolation & purification*; D005285:Fermentation; D008386:Marine Biology; D010880:Piperidines / Q000737:chemistry / Q000302:isolation & purification*; D012231:Rhizobium / Q000737:chemistry* / Q000145:classification / Q000378:metabolism; D014871:Water Microbiology
D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D004187:Disaccharides; D010880:Piperidines; C077293:sesbanimide