title: Cost-effectiveness of measles outbreak intervention strategies.
abstract: In this study, we compared the likely cost-effectiveness of alternative strategies for controlling a school-based measles outbreak. The analysis involved assessing the expected costs and number of cases in a school-based outbreak of measles, with no intervention and with each of six control strategies. The marginal cost per case prevented ranged from $32.90 when only previously unvaccinated school children were offered vaccination to $6795 when vaccination was extended to the siblings of school children aged 6 to 12 months. This study provided further evidence of the cost-effectiveness of vaccination in outbreak control, and yielded useful information to inform control strategies in the event of a school-based outbreak. Decisions about which groups of children to aim at and whether to conduct school-based clinics will be influenced by local circumstances, particularly the baseline measles vaccination rate and the measles attack rate among infants.
authors.affiliation: Department of Public Health and Community Medicine, University of Sydney, NSW.
authors.forename: A
authors.initials: A
authors.lastname: Shiell
authors.forename: L R
authors.initials: LR
authors.lastname: Jorm
authors.forename: R
authors.initials: R
authors.lastname: Carruthers
authors.forename: G J
authors.initials: GJ
authors.lastname: Fitzsimmons
mesh_terms: D000704:Analysis of Variance; D001315:Australia / Q000453:epidemiology; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003140:Communicable Disease Control / Q000191:economics* / Q000379:methods; D003362:Cost-Benefit Analysis; D004196:Disease Outbreaks / Q000191:economics* / Q000517:prevention & control; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008457:Measles / Q000191:economics / Q000453:epidemiology*; D008458:Measles Vaccine / Q000008:administration & dosage* / Q000191:economics; D014611:Vaccination / Q000191:economics*
chemical_list: D008458:Measles Vaccine