The data presented by Jelinek et al. (1997) should not be taken as evidence against an association between resistance to sulphadoxine-pyrimethamine (S/P) and mutations in the dihydrofolate reductase gene of Plasmodium falciparum.
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D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D002648:Child; D004338:Drug Combinations; D004352:Drug Resistance, Microbial; D006801:Humans; D009154:Mutation; D010963:Plasmodium falciparum / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics*; D011739:Pyrimethamine / Q000494:pharmacology*; D013413:Sulfadoxine / Q000494:pharmacology*; D013762:Tetrahydrofolate Dehydrogenase / Q000235:genetics*
D000962:Antimalarials; D004338:Drug Combinations; C001205:fanasil, pyrimethamine drug combination; D013413:Sulfadoxine; D013762:Tetrahydrofolate Dehydrogenase; D011739:Pyrimethamine