title: [Alzheimer's disease: beta amyloid and lipid metabolism].
abstract: Amyloid deposits found in brains of Alzheimer's disease. Down's syndrome and normal aged individuals are composed mainly of aggregated amyloid beta (Ab), soluble form which is a normal protein. We previously reported that soluble Ab (sAb) in normal human plasma and cerebrospinal fluid is complexed to high density lipoprotein (HDL). Consequences of sAb association with the HDL and Ab involvement in the lipid turnover are discussed herein.
authors.affiliation: Russian Academy of Medical Sciences, School of Medicine, Russian Peoples, Friendship University, Moscow, Russia. koudin@imb.imb.ac.ru
authors.forename: N V
authors.initials: NV
authors.lastname: Kudinova
authors.forename: A R
authors.initials: AR
authors.lastname: Kudinov
authors.forename: T T
authors.initials: TT
authors.lastname: Berezov
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000544:Alzheimer Disease / Q000097:blood*; D000595:Amino Acid Sequence; D016229:Amyloid beta-Peptides / Q000097:blood* / Q000235:genetics; D000818:Animals; D004314:Down Syndrome / Q000097:blood; D006801:Humans; D050356:Lipid Metabolism; D008969:Molecular Sequence Data
chemical_list: D016229:Amyloid beta-Peptides
vernacular_title: Bolezn' Al'tsgeĭmera: amiloid beta i metabolizm lipidov.