[Monitoring growth factors during wound healing as the basic principle of effective clinical growth factor therapy?].
The microenvironment of healing human skin wounds is continuously monitored by a cutaneous chamber model. In recent studies in patients, baseline data for barrier function, temporal profiles of growth factors, and other mediators of healing were established. This model may be useful in clinical research of modulators of healing and wound pharmacology.
Vogt
P M
PM
Klinik für Plastische Chirurgie und Schwerbrandverletzte, Handchirurgie-Zentrum, BG-Kliniken Bergmannsheil, Ruhr-Universität Bochum.
Wagner
D
D
Lehnhardt
M
M
Peter
F W
FW
Steinau
H U
HU
D000818:Animals; D001458:Bandages; D006133:Growth Substances / Q000378:metabolism*; D006801:Humans; D012884:Skin Window Technique; D013552:Swine; D014945:Wound Healing / Q000502:physiology*
D006133:Growth Substances
Monitoring von Wachstumsfaktoren während der Wundheilung als Grundlage einer effizienten klinischen Wachstumsfaktortherapie?