Selection of functional DNAs which bind to a transition state analog.
Selection of single strand DNA molecules which bind to a transition state analogue of carboxyl ester hydrolysis was demonstrated. After the 9th round of selection, ssDNAs with the affinity to TSA were enriched.
Kato
T
T
Research Center for Advanced Science and Technology, University of Tokyo, Japan.
Ikebukuro
K
K
Karube
I
I
D017151:Antibodies, Catalytic / Q000737:chemistry; D001483:Base Sequence; D001665:Binding Sites; D017931:DNA Primers; D004277:DNA, Single-Stranded / Q000737:chemistry*; D006868:Hydrolysis; D009838:Oligodeoxyribonucleotides / Q000737:chemistry*; D016133:Polymerase Chain Reaction; D011166:Porphyrins / Q000737:chemistry; D016337:RNA, Catalytic / Q000737:chemistry; D013816:Thermodynamics
D017151:Antibodies, Catalytic; D017931:DNA Primers; D004277:DNA, Single-Stranded; D009838:Oligodeoxyribonucleotides; D011166:Porphyrins; D016337:RNA, Catalytic