A clinical evaluation of non-steroidal anti-inflammatory drugs (NSAIDS) as adjuncts in the management of periodontal disease.
Several effectors and mediators of inflammation have been identified as principle factors in periodontal disease progression. It has been reported that topical and systemic application of flurbiprofen (non-steroidal anti-inflammatory drug) reduced the rate of alveolar bone loss as well as signs of gingival inflammation. Twenty rapidly progressive as well as juvenile periodontitis patients were included in the present study. Results of the present study showed a significant reduction in pocket depth & gingival index in the experimental group over the control group. Radiographs revealed more bone fill in the experimental group over the control group.
Aboul-Dahab
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Department of Oral Medicine and Periodontology, Faculty of Oral and Dental Medicine, Cairo University.
D010520:Aggressive Periodontitis / Q000175:diagnosis / Q000188:drug therapy*; D000704:Analysis of Variance; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D012534:Dental Scaling; D004341:Drug Evaluation; D006801:Humans; D007052:Ibuprofen / Q000627:therapeutic use*; D010512:Periodontal Index; D010514:Periodontal Pocket / Q000175:diagnosis / Q000188:drug therapy*; D013997:Time Factors
D000894:Anti-Inflammatory Agents, Non-Steroidal; D007052:Ibuprofen