title: Distribution of human platelet antigens in a Chinese population.
abstract: We report the distribution of the human platelet antigens HPA-1, -2, -3, -4 and -5 as determined using the polymerase chain reaction with sequence-specific primers in 100 random, healthy Chinese in Hong Kong. The HPA-1a, -2a, -4a and -5a genes were present in every sample tested, HPA-1b, -2b and -5b were rare, and the sample was monomorphic for HPA-4a. HPA-3a and -3b genes showed frequencies of 0.525 and 0.475 respectively. There was no departure from Hardy-Weinberg equilibrium in any of the five HPA systems studied.
authors.affiliation: Department of Pathology, The University of Hong Kong, Hong Kong.
authors.forename: Y W
authors.initials: YW
authors.lastname: Chang
authors.forename: J
authors.initials: J
authors.lastname: Mytilineos
authors.forename: G
authors.initials: G
authors.lastname: Opelz
authors.forename: B R
authors.initials: BR
authors.lastname: Hawkins
mesh_terms: D016824:Antigens, Human Platelet / Q000145:classification / Q000235:genetics*; D044466:Asian People / Q000235:genetics*; D006801:Humans; D016133:Polymerase Chain Reaction; D011153:Population
chemical_list: D016824:Antigens, Human Platelet