[Disturbance of equilibrium between blood levels of antioxidant and prooxidant metalloproteins in pain stress in children].
Molecular mechanisms of the trauma stress of different origins in children to some extent is related to the quantitative changes of blood superoxide dismutase, catalase, ceruloplasmin, transferrin, cytochromes b5, b558III, b558IV and suprol. Non adequate changes of antioxidant (superoxide dismutase, catalase, ceruloplasmin, transferrin) and newly discovered prooxidant (cytochromes b5, b558III, b558IV, suprol) metalloproteins, as well as serum and erythrocyte cytochrome b5 depend on characteristic and duration of trauma stress caused by extremity fractures in children. This is due to the different mechanisms of adaptation to trauma stress.
Shakarian
M A
MA
Institute of Molecular Biology, National Academy of Sciences of Armenija, Erevan.
Karagezian
K G
KG
Simonian
M A
MA
Babloian
A S
AS
D000222:Adaptation, Physiological; D000293:Adolescent; D000975:Antioxidants / Q000378:metabolism*; D002374:Catalase / Q000097:blood; D002570:Ceruloplasmin / Q000378:metabolism; D002648:Child; D003573:Cytochrome b Group / Q000097:blood; D004912:Erythrocytes / Q000378:metabolism; D050723:Fractures, Bone / Q000097:blood / Q000150:complications; D006801:Humans; D008297:Male; D008667:Metalloproteins / Q000097:blood*; D010146:Pain / Q000097:blood* / Q000150:complications; D013312:Stress, Physiological / Q000097:blood* / Q000209:etiology; D013482:Superoxide Dismutase / Q000097:blood; D014168:Transferrin / Q000378:metabolism
D000975:Antioxidants; D003573:Cytochrome b Group; D008667:Metalloproteins; D014168:Transferrin; D002374:Catalase; D013482:Superoxide Dismutase; D002570:Ceruloplasmin
Narushenie ravnovesiia mezhdu urovnem antioksidantnykh i prooksidantnykh metalloproteinov krovi pri bolevom stresse u deteĭ.