title: [Primary malignant mediastinal melanoma. Apropos of a case].
abstract: We report the case of a 57-year-old patient with primary malignant melanoma of the mediastinum who survived nine months despite immunotherapy, radiotherapy and chemotherapy. The primary nature of the intrathoracic melanoma was difficult to prove. Definitive diagnosis was based on the uniform morphology of the melanoma which showed junctional anomalies at the histology examination with tracheo-bronchial and esophageal localizations as well as on the absence of other patent or formerly resected melanocyte-rich localizations (skin, mucosa, ocular) at clinical examination and autopsy.
authors.affiliation: Service de Pneumologie, unité de soins J. P. Battesti.
authors.forename: E
authors.initials: E
authors.lastname: Cordina
authors.forename: P S
authors.initials: PS
authors.lastname: Assouline
authors.forename: C
authors.initials: C
authors.lastname: Krespine
authors.forename: A
authors.initials: A
authors.lastname: Soulier
authors.forename: Y
authors.initials: Y
authors.lastname: Soulier
authors.forename: P
authors.initials: P
authors.lastname: Dournovo
authors.forename: B
authors.initials: B
authors.lastname: Lebeau
mesh_terms: D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology; D008545:Melanoma / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology; D008875:Middle Aged
vernacular_title: Mélanome malin primitif médiastinal. A propos d'un cas.