Drastic elevation of serum CA125, CA72-4 and CA19-9 levels during menses in a patient with probable endometriosis.
Levels of CA125, CA72-4 and CA19-9, serum markers for ovarian cancer, were measured throughout menstrual cycles in a patient with probable pelvic endometriosis. The patient had CA125 levels >1000 U ml(-1), CA72-4>10 U ml(-1) and CA19-9>150 U ml(-1) during but not after menses (P<0.01). In luteal phase and premenstrual phase, the levels of these markers seemed to return normal ranges, although CA125 remained over the upper normal limit. Knowledge that a physiological elevation of these markers may occur during menses might avoid misinterpretation.
Imai
A
A
Department of Obstetrics and Gynecology, Gifu University School of Medicine, Tsukasamachi, Japan.
Horibe
S
S
Takagi
A
A
Takagi
H
H
Tamaya
T
T
D000291:Adnexal Diseases / Q000150:complications; D000328:Adult; D015295:Antigens, Tumor-Associated, Carbohydrate / Q000097:blood*; D002064:Buserelin / Q000627:therapeutic use; D018394:CA-125 Antigen / Q000097:blood*; D018395:CA-19-9 Antigen / Q000097:blood*; D003560:Cysts / Q000150:complications; D004715:Endometriosis / Q000150:complications / Q000188:drug therapy / Q000276:immunology*; D005260:Female; D006801:Humans; D008183:Luteal Phase; D008597:Menstrual Cycle
D015295:Antigens, Tumor-Associated, Carbohydrate; D018394:CA-125 Antigen; D018395:CA-19-9 Antigen; C083825:CA-72-4 antigen; D002064:Buserelin