Removal of serum beta-2 microglobulin using high-performance membranes and analysis of changes in serum BMG levels after dialysis.
OBJECTIVE
The present study was undertaken to analyze the beta2-microglobulin (BMG)-removing efficiency of high-performance membranes (HPMs) in relation to changes in serum BMG levels after dialysis.


METHODS
In 10 stable dialysis patients, six different HPMs were used in a crossover method. Serum BMG levels were measured immediately before dialysis, immediately after, 4 h after, and immediately before the next dialysis. On the basis of these measurements, the BMG removal rate was calculated.


RESULTS
The BMG removal rate as calculated on the basis of the BMG level immediately after dialysis was 11.29% higher than the rate calculated on the basis of the BMG level 4 h after dialysis.


CONCLUSIONS
The BMG removal rate can be overestimated if it is calculated on the basis of the BMG level immediately after dialysis.
Yasuhiro
I
I
2nd Division of Internal Medicine, Kansai Medical University, Kohori Hospital, Neyagawa, Osaka, Japan.
Eiichi
N
N
Mineo
O
O
Muneto
Y
Y
Toshihiro
I
I
Masahiro
F
F
Yoshifumi
N
N
Masahito
M
M
Ryuichi
M
M
D018592:Cross-Over Studies; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood / Q000628:therapy; D007688:Kidneys, Artificial; D008567:Membranes, Artificial; D006435:Renal Dialysis / Q000295:instrumentation*; D013997:Time Factors; D001613:beta 2-Microglobulin / Q000032:analysis* / Q000378:metabolism
D008567:Membranes, Artificial; D001613:beta 2-Microglobulin