Measurement of chemical shifts and coupling constants for glutamate and glutamine.
Proton chemical shifts and coupling constants were obtained for glutamate and glutamine in water (D2O) at pH = 6.6. Initial chemical shift and coupling constant values obtained from experimental spectra were refined using a spectral simulation and optimization program to get a complete set of values that could not otherwise be measured directly from the experimental spectra due to strong spin-spin couplings. These values are essential for automated spectral fitting procedures that require a priori information.
Govindaraju
V
V
Department of Radiology, University of California San Francisco, VA Medical Center, 94121, USA.
Basus
V J
VJ
Matson
G B
GB
Maudsley
A A
AA
D001921:Brain / Q000033:anatomy & histology*; D003198:Computer Simulation; D005583:Fourier Analysis; D018698:Glutamic Acid / Q000032:analysis*; D005973:Glutamine / Q000032:analysis*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D009682:Magnetic Resonance Spectroscopy
D005973:Glutamine; D018698:Glutamic Acid