[Late effects of ionizing radiations on head and neck region tissues].
Numerous structures are included in the irradiated volume of patients presenting with head and neck cancer: skin, mucosa, bone, teeth, cartilage, muscles, salivary glands, etc. Curative intent treatment of such tumours requires aggressive approach which can lead to severe sequellae. These sequellae are in most cases dose-dependent and volume-dependent. However, an appropriate technique might decrease the severity of such sequellae. Details of these late changes are presented, including their pathophysiology, clinical syndromes, potential treatment, and prevention.
Mazeron
J J
JJ
Centre des tumeurs, groupe hospitalier Pitié-Salpêtrière, Paris, France.
Grimard
L
L
D004307:Dose-Response Relationship, Radiation; D004423:Ear / Q000473:pathology / Q000528:radiation effects*; D006801:Humans; D007830:Larynx / Q000473:pathology / Q000528:radiation effects*; D008336:Mandibular Diseases / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D009059:Mouth Diseases / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D010025:Osteoradionecrosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D011836:Radiation Tolerance; D011878:Radiotherapy / Q000009:adverse effects* / Q000379:methods; D012469:Salivary Glands / Q000473:pathology / Q000528:radiation effects; D012886:Skull / Q000473:pathology / Q000528:radiation effects; D013284:Stomatognathic System / Q000473:pathology / Q000528:radiation effects*
Effets tardifs des radiations ionisantes sur les tissus de la sphère otorhinolaryngologique.