[The pathomorphological characteristics of duodenal peptic ulcer in the victims of the accident at the Chernobyl Atomic Electric Power Station: changes in the gastric mucosa].
Gastrobiopsies were studied from patients with duodenal ulcer, 62 of whom took part in the elimination of the effects of the Chernobyl Nuclear Power Plant breakdown, 33 were permanent residents in the territories affected by radioactive contamination, and 36 formed the control group. Several distinguishing features were noted in chronic Helicobacter gastritis in victims of Chernobyl accident versus control, such as higher degree and activity of the inflammatory process spreading over large tissue areas, with Helicobacter pylori being recordable in the gastric mucosa in highly increased numbers, and more frequent occurrence of atrophic changes. Incorporation of radionuclides and external irradiation at dose levels exceeding 25 cause most significant disturbances in regeneration of epithelium, with its enterolyzation and dysplasia going on, which fact makes the risk of neoplastic transformations higher.
Degtiareva
L V
LV
Moroz
G Z
GZ
D000328:Adult; D001706:Biopsy; D002908:Chronic Disease; D004381:Duodenal Ulcer / Q000382:microbiology / Q000473:pathology*; D005753:Gastric Mucosa / Q000382:microbiology / Q000473:pathology* / Q000528:radiation effects; D016481:Helicobacter Infections / Q000382:microbiology / Q000473:pathology; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D011210:Power Plants; D011832:Radiation Injuries / Q000382:microbiology / Q000473:pathology*; D018788:Radioactive Hazard Release; D014455:Ukraine
Patomorfologicheskie osobennosti iazvennoĭ bolezni dvenadtsatiperstnoĭ kishki u lits, postradavshikh vsledstvie avarii na ChAES: izmeneniia slizistoĭ obolochki zheludka.