title: Landscaping the cancer terrain.
authors.affiliation: Molecular Genetics Laboratory, Johns Hopkins Oncology Center, Baltimore, MD 21231, USA.
authors.forename: K W
authors.initials: KW
authors.lastname: Kinzler
authors.forename: B
authors.initials: B
authors.lastname: Vogelstein
mesh_terms: D002455:Cell Division; D015179:Colorectal Neoplasms / Q000235:genetics* / Q000473:pathology; D004268:DNA-Binding Proteins; D004847:Epithelial Cells / Q000473:pathology; D016147:Genes, Tumor Suppressor; D020022:Genetic Predisposition to Disease; D006223:Hamartoma Syndrome, Multiple / Q000235:genetics* / Q000473:pathology; D006801:Humans; D007417:Intestinal Polyps / Q000235:genetics* / Q000473:pathology; D009154:Mutation; D009369:Neoplasms / Q000235:genetics* / Q000473:pathology; D051059:PTEN Phosphohydrolase; D010744:Phosphoric Monoester Hydrolases; D017027:Protein Tyrosine Phosphatases / Q000235:genetics; D051901:Smad4 Protein; D017154:Stromal Cells / Q000473:pathology; D015534:Trans-Activators / Q000235:genetics; D025521:Tumor Suppressor Proteins
chemical_list: D004268:DNA-Binding Proteins; C497796:SMAD4 protein, human; D051901:Smad4 Protein; D015534:Trans-Activators; D025521:Tumor Suppressor Proteins; D010744:Phosphoric Monoester Hydrolases; D017027:Protein Tyrosine Phosphatases; D051059:PTEN Phosphohydrolase; C494929:PTEN protein, human