[The safety and reactogenicity of the new probiotic subalin for volunteers].
Data are presented on the study of innocuousness and reactogenicity of a new recombinant probiotic subalin characterized by antibacterial and antiviral activity. Volunteers who took subalin (one dose twice a day for 10 days) were under observation at Kyiv Scientific-Research Institute of Epidemiology and Infectious Diseases of the Ministry of Public Health of Ukraine. They carried out clinical and bacteriological investigations during administration and after termination of the course of oral administration of subalin testified to its innocuousness as well as to the absence of any side-effects.
Sorokulova
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IB
Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, Kyiv.
D000284:Administration, Oral; D000328:Adult; D000906:Antibodies / Q000097:blood / Q000187:drug effects; D001412:Bacillus subtilis; D016470:Bacteremia / Q000382:microbiology; D001437:Bacteriuria / Q000382:microbiology; D001685:Biological Factors / Q000008:administration & dosage / Q000009:adverse effects*; D004341:Drug Evaluation; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D007372:Interferons / Q000097:blood / Q000187:drug effects / Q000276:immunology; D008297:Male; D008875:Middle Aged; D019936:Probiotics / Q000008:administration & dosage / Q000009:adverse effects*; D011994:Recombinant Proteins / Q000008:administration & dosage / Q000009:adverse effects; D013997:Time Factors
D000906:Antibodies; D001685:Biological Factors; D011994:Recombinant Proteins; C112120:subalin; D007372:Interferons
Izuchenie bezopasnosti i reaktogennosti novogo probiotika subalina dlia dobrovol'tsev.