title: Salt-promoted adsorption of proteins onto amphiphilic agarose-based adsorbents. II. Effects of salt and salt concentration.
abstract: The effects of different types of salts and salt concentrations on the selectivity in the adsorption of serum proteins have been compared for the amphiphilic agarose-based adsorbents Phenyl-Sepharose, Octyl-Sepharose, butyl-agarose and mercaptopyridine-derivatized agarose. By use of multivariate analysis, the complex interrelationships for the different combined effects were evaluated. From these analyses conclusions about similarities and/or dissimilarities in the mechanisms involved in adsorption of proteins on respective adsorbent were made.
authors.affiliation: Department of Chemical Engineering, Mälardalen University, Eskilstuna, Sweden.
authors.forename: S
authors.initials: S
authors.lastname: Oscarsson
authors.forename: P
authors.initials: P
authors.lastname: Kårsnäs
mesh_terms: D000085:Acetates / Q000737:chemistry; D000327:Adsorption; D001798:Blood Proteins / Q000737:chemistry*; D002847:Chromatography, Agarose / Q000379:methods*; D009994:Osmolar Concentration; D011189:Potassium Chloride / Q000737:chemistry; D012492:Salts / Q000737:chemistry*; D019346:Sodium Acetate / Q000737:chemistry; D012965:Sodium Chloride / Q000737:chemistry; D013431:Sulfates / Q000737:chemistry
chemical_list: D000085:Acetates; D001798:Blood Proteins; D012492:Salts; D013431:Sulfates; C031512:potassium sulfate; D012965:Sodium Chloride; D019346:Sodium Acetate; D011189:Potassium Chloride; C018824:ammonium acetate