[The role of carnitine in human lipid metabolism].
Carnitine is an important nutrient that is present in diet (particularly in meat and dairy products) and is synthesized from amino acids. Carnitine has two principal functions in the organism. One is to transport long-chain fatty acids into the mitochondrion. The second function of carnitine is to regulate the intramitochondrial ratio of acylocoenzyme A to free coenzyme A. This function is important because it allows to remove excessive (and potentially toxic) short- and medium-chain fatty acids from the mitochondrion, and because it maintains sufficient free coenzyme A within the mitochondrion to support energy metabolism.
Pietrzak
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Studium Doktoranckiego Slaskiej Akademii Medycznej w Katowicach.
Opala
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D002331:Carnitine / Q000378:metabolism*; D003065:Coenzyme A / Q000378:metabolism; D004734:Energy Metabolism; D005227:Fatty Acids / Q000378:metabolism; D006801:Humans; D050356:Lipid Metabolism; D008928:Mitochondria / Q000378:metabolism; D012016:Reference Values
D005227:Fatty Acids; D002331:Carnitine; D003065:Coenzyme A
Rola karnityny w przemianie lipidowej u człowieka.