title: [Programmed complex for planning fractionated regimens of malignant tumor irradiation by local adjustment of mathematical model parameters].
abstract: The accuracy of planning the fractionated radiation regimens may be enhanced by the proposed method of local adjustment of its parameters. For planning the fractionated radiation regimens in practical radiology, TDF was used to design a programmed complex (PC) which defines the main radiological parameters of a radiation plan as a system of interchangeable values in remote, contact, and combined radiation therapy for uniform and nonuniform dose fractionation regimens. PC allows a radiologist to actively use his clinical observation for local adjustment of mathematical model parameters and for planning the fractionated radiation regimens. The method of local adjustment of mathematical model parameters for dose fractionation is applicable to lung tissue radiation. Its advantage is that it permits one to consider the complexity of the organism exposed to radiation and, to a definite extent, to minimize the possible inadequacy of the used mathematical model of dose fractionation.
authors.forename: L Ia
authors.initials: LIa
authors.lastname: Klepper
mesh_terms: D019583:Dose Fractionation, Radiation; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy; D008962:Models, Theoretical; D009369:Neoplasms / Q000532:radiotherapy*; D011836:Radiation Tolerance
vernacular_title: Programmnyĭ kompleks dlia planirovaniia fraktsionirovannykh skhem oblucheniia zlokachestvennykh opukholeĭ metodom lokal'noĭ nastroĭki parametrov matematicheskikh modeleĭ.