title: [The problem of genetic-biochemical basis of individual sensitivity in occupational medicine].
abstract: Human sensitivity to various factors of occupational environment (toxic chemicals, aerosols with mostly fibrogenic effects, etc.) depends on individual hereditary features determining adaptation or dysadaptation with subsequent disease. Studies of propensity and resistance in individuals exposed to occupational hazards should cover analysis of genetic basis for polymorphism in certain biochemical systems determining relationships between hazards detoxication and activation, DNA alteration and repair.
authors.forename: L A
authors.initials: LA
authors.lastname: Tarasova
authors.forename: L P
authors.initials: LP
authors.lastname: Kuz'mina
authors.forename: A A
authors.initials: AA
authors.lastname: Kasparov
mesh_terms: D003580:Cytochromes / Q000235:genetics; D005819:Genetic Markers; D006801:Humans; D009784:Occupational Diseases / Q000209:etiology / Q000235:genetics* / Q000276:immunology*; D016273:Occupational Exposure / Q000009:adverse effects; D016272:Occupational Health; D010641:Phenotype
chemical_list: D003580:Cytochromes; D005819:Genetic Markers
vernacular_title: Problema genetiko-biokhimicheskikh osnov individual'noĭ chuvstvitel'nosti v meditsine truda.