A negative component on event related potential recorded in the drowsy state.
Behavior of event related potential (ERP) components in the drowsy state was examined in nine subjects using oddball paradigm. A component with peak latency of 300 msec, N300, was superimposed on ERP in the drowsy state. N300 appeared also in stage 1 of NREM sleep and closely resembled vertex sharp wave evoked by sound stimulation in both scalp distribution and peak latency. It was suggested that N300 recorded in the drowsy state and vertex sharp wave recorded in stage 1 of NREM sleep are generated by the identical synchronizing mechanism in the brain.
Sekine
A
A
Psychiatric Clinic, Akita City Hospital, Akita, Japan.
Niiyama
Y
Y
Fujiwara
R
R
Satoh
N
N
Fushimi
M
M
Kutsuzawa
O
O
Hishikawa
Y
Y
D000328:Adult; D001143:Arousal / Q000502:physiology*; D002540:Cerebral Cortex / Q000502:physiology; D003265:Contingent Negative Variation / Q000502:physiology*; D003344:Cortical Synchronization; D004569:Electroencephalography; D005072:Evoked Potentials, Auditory / Q000502:physiology; D006801:Humans; D008297:Male; D010897:Pitch Discrimination / Q000502:physiology; D011930:Reaction Time / Q000502:physiology; D012894:Sleep Stages / Q000502:physiology*; D014851:Wakefulness / Q000502:physiology