Cerebral blood volume in the sleep measured by near-infrared spectroscopy.
We investigated the relationship between hemodynamic changes in the cortex measured by near-infrared spectroscopy (NIRS) and the polysomnographic changes during sleep. Four healthy male volunteers participated in the study. Near-infrared spectroscopy measuring and polysomnographic recordings were done simultaneously during sleep. In many case, oxy-hemoglobin (oxy-Hb) decreased and deoxy-hemoglobin (deoxy-Hb) increased during the transition from wakefulness to sleep, and oxy-Hb increased toward deep sleep. Oxy-Hb and deoxy-Hb had larger fluctuations during REM sleep than those during non-REM sleep. During REM sleep, oxy-Hb often showed a lower level and deoxy-Hb showed a higher level than those during the preceding and following non-REM sleep.
Shiotsuka
S
S
Saitama Comprehensive Mental Health Center, Japan.
Atsumi
Y
Y
Ogata
S
S
Yamamoto
R
R
Igawa
M
M
Takahashi
K
K
Hirasawa
H
H
Koyama
K
K
Maki
A
A
Yamashita
Y
Y
Koizumi
H
H
Toru
M
M
D000328:Adult; D001341:Autonomic Nervous System / Q000502:physiology; D001810:Blood Volume / Q000502:physiology*; D001921:Brain / Q000098:blood supply*; D002540:Cerebral Cortex / Q000098:blood supply; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D008297:Male; D010108:Oxyhemoglobins / Q000378:metabolism; D017286:Polysomnography / Q000295:instrumentation*; D012016:Reference Values; D012894:Sleep Stages / Q000502:physiology*; D012895:Sleep, REM / Q000502:physiology; D019265:Spectroscopy, Near-Infrared / Q000295:instrumentation*; D014851:Wakefulness / Q000502:physiology
D006454:Hemoglobins; D010108:Oxyhemoglobins; C100003:deoxyhemoglobin