Studies on arylmethyltriazinone derivatives-Part II. Synthesis and antifungal properties of 2-aminomethyl-4-(arylidene)amino-6-arylmethyl- 3-mercapto-1,2,4-triazin-5(4H)-ones.
The preparation of twenty new 2-aminomethyl-4-(arylidene)amino- 6-arylmethyl-3-mercapto-1,2,4-triazin-5(4H)-ones(4) is described. The structural elucidation of all the compounds is carried out on the basis of analytical and spectral data. The newly synthesized compounds are evaluated for their antifungal activity against Candida albicans and Paecileomyces variotti.
Holla
B S
BS
Department of Chemistry, Mangalore University Mangalagangotri, India.
Gonsalves
R
R
Shivananda
M K
MK
D000935:Antifungal Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects; D005658:Fungi / Q000187:drug effects*; D008826:Microbial Sensitivity Tests; D014227:Triazines / Q000138:chemical synthesis* / Q000494:pharmacology
D000935:Antifungal Agents; D014227:Triazines