[Continuous spike-wave activity during sleep. Electroencephalographic and clinical features].
Seventeen children were retrospectively evaluated. They exhibited continuous spike-wave activity during slow wave sleep (CSWS). Five of these had only speech problems and seizures (Landau-Kleffner syndrome) (group 1). The other cases had developmental milestones acquisition delay and/or mental retardation (group 2). Epileptic seizures were present in 11 of these, tetraparesis was observed in 5, hemiparesis in 2, microcephaly in 2 and behavior disturbances in 4 cases. The electroencephalogram showed in all cases diffuse CSWS. Group 1 showed diffuse activity, at times accentuated in the centrotemporal region (4/5). Group 2 had widespread discharges, including multifocal activity (5/12), sometimes with anterior predominance (7/12). We concluded that CSWS is a non specific electrographic pattern observed in some types of epilepsy in childhood that have different clinical presentation. It has however some topographic differentiation, depending upon the lesional sites.
Guilhoto
L M
LM
Departamento de Neurologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HC/FMSUP), Brasil.
Machado-Haertel
L R
LR
Manreza
M L
ML
Diament
A J
AJ
D001921:Brain / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007223:Infant; D018887:Landau-Kleffner Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D008297:Male; D012189:Retrospective Studies; D012890:Sleep / Q000502:physiology*
Espícula-onda contínua durante o sono. Aspectos clínicos e eletrencefalográficos.