Fine-needle aspiration cytology and immunocytochemistry of Hodgkin's disease, suppurative type.
We describe 3 cases of Hodgkin's disease (HD) of unusual suppurative type, which were diagnosed on fine-needle aspirates. The smears were dominated by neutrophils, macrophages, and cellular debris. Only a few large, atypical cells of Hodgkin and Reed-Sternberg type were observed. The differential diagnoses of such smears include infectious mononucleosis, tuberculosis, metastatic lymph node involvement, non-Hodgkin's large-cell anaplastic Ki-1-positive lymphomas, T-cell-rich B-cell lymphomas, and peripheral T-cell lymphomas of mixed type. Immunocytochemistry identified the large atypical cells as CD 30 (BerH2)-positive and negative for CD 45 (LCA) in cytospin material from 2 patients, which allowed a conclusive diagnosis of HD.
Tani
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E
Department of Pathology and Cytology, Karolinska Hospital, Stockholm, Sweden.
Ersöz
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C
Svedmyr
E
E
Skoog
L
L
D000293:Adolescent; D000328:Adult; D001707:Biopsy, Needle; D005260:Female; D006689:Hodgkin Disease / Q000276:immunology / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D013492:Suppuration