[Use of adjuvant therapy in patients with metastasis of melanoma to regional lymph nodes].
The results of treatment of 276 patients with cutaneous melanoma of T1-4N1M0 stage were analyzed. The irradiation therapy conduction did not influence the result of surgical treatment. The trustworthy improvement of three-year survival index of patients after the radical operation conduction was noted under the influence of the endolymphatic cytostatic therapy. The result of preoperative endolymphatic chemotherapy and interferon therapy conduction is quite similar.
Korovin
S I
SI
D000328:Adult; D000964:Antimetabolites, Antineoplastic / Q000008:administration & dosage; D018906:Antineoplastic Agents, Alkylating / Q000008:administration & dosage; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D017024:Chemotherapy, Adjuvant; D003131:Combined Modality Therapy; D003520:Cyclophosphamide / Q000008:administration & dosage; D005260:Female; D006801:Humans; D007272:Injections, Intralymphatic; D007370:Interferon Type I / Q000008:administration & dosage; D008197:Lymph Node Excision; D008207:Lymphatic Metastasis; D008297:Male; D008545:Melanoma / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D008727:Methotrexate / Q000008:administration & dosage; D008875:Middle Aged; D011300:Preoperative Care; D011447:Prospidium / Q000008:administration & dosage; D011994:Recombinant Proteins; D012878:Skin Neoplasms / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D013997:Time Factors
D000964:Antimetabolites, Antineoplastic; D018906:Antineoplastic Agents, Alkylating; D007370:Interferon Type I; D011994:Recombinant Proteins; D011447:Prospidium; D003520:Cyclophosphamide; D008727:Methotrexate
Primenenie ad"iuvantnoĭ terapii u bol'nykh s metastazami melanomy v regionarnykh limfaticheskikh uzlakh.