Depression and short REM latency in subjects with chronic fatigue syndrome.
OBJECTIVE
The hypothesized polysomnographic marker for depression, Rapid Eye Movement Latency (REML), was used to investigate two groups of subjects; Chronic Fatigue Syndrome (CFS)-not depressed and CFS-depressed.


METHODS
CFS subjects were classified into depressed and not depressed groups, using the Diagnostic Interview Schedule (DIS), and subsequently were studied in a sleep laboratory to ascertain REML.


RESULTS
Short REML showed a statistically significant correlation with the depressed state in CFS subjects.


CONCLUSIONS
Short REM latency is associated with depression in the CFS population.
Morehouse
R L
RL
Department of Psychiatry, Dalhousie University, QEII Health Sciences Centre, Halifax, Nova Scotia.
Flanigan
M
M
MacDonald
D D
DD
Braha
D
D
Shapiro
C
C
D000293:Adolescent; D000328:Adult; D003866:Depressive Disorder / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D015673:Fatigue Syndrome, Chronic / Q000175:diagnosis / Q000503:physiopathology* / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D011930:Reaction Time / Q000502:physiology*; D012016:Reference Values; D012894:Sleep Stages / Q000502:physiology; D012895:Sleep, REM / Q000502:physiology*