[Dysembryoplastic neuroepithelial tumor. Case report].
Dysembryoplastic neuroepithelial tumor (DNT) is a relatively new neuroepithelial neoplasm that was first described by Daumas-Duport et al. in 1988. It was incorporated in the revised World Health Organization classification of brain tumors in 1993. The authors present the first case of DNT reported in the Latin-American literature. A 16-year-old woman had been found at age of five years to have complex partial seizures accompanied by secondary generalization. She was treated with various anti-epileptic drugs but always with incomplete control of seizures activity. Neurological examination was normal. Magnetic resonance imaging demonstrated a lesion in the left temporal lobe. She underwent a craniotomy with complete resection of the tumor. Histological study showed atypical neuroglial proliferation characteristic of DNT. Monoclonal antibody immunostaining for glial fibrillary acidic protein and S-100 protein confirmed the glial component, and neuronal specific enolase and synaptophysin emphasized the neuronal component.
Torres
L F
LF
Serviço de Anatomia Patológica, Hospital Nossa Senhora das Graças, Curitiba, Brasil.
Werner
B
B
Souza
D S
DS
Araújo
J C
JC
D000293:Adolescent; D004827:Epilepsy; D005260:Female; D006801:Humans; D018302:Neoplasms, Neuroepithelial / Q000503:physiopathology*; D013724:Teratoma / Q000503:physiopathology*
Tumor disembrioplástico neuroepitelial. Relato de caso.