Photosensitivity reaction to fluoxetine and alprazolam.
We report the case of a male individual who developed a severe photosensitive reaction after sun exposure during therapy with fluoxetin 20 mg bid plus alprazolam 0.25 mg bid due to depressive disturbances. The patients, of North-African origin, was not taking other prescription medications nor over the counter products; in the past he had never shown any reaction to sunlight nor had ever used sun protective agents because of its phenotypical skin mark. Three months later, after a second photosensitive reaction, the pharmacological therapy was finally discontinued.
Pazzagli
L
L
Pharmacy Department, Azienda Sanitaria di Firenze, Italy.
Banfi
R
R
Borselli
G
G
Semmola
M V
MV
D000328:Adult; D000525:Alprazolam / Q000008:administration & dosage / Q000009:adverse effects*; D018687:Antidepressive Agents, Second-Generation / Q000008:administration & dosage / Q000009:adverse effects*; D003863:Depression / Q000188:drug therapy; D005002:Ethiopia / Q000208:ethnology; D005473:Fluoxetine / Q000008:administration & dosage / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010787:Photosensitivity Disorders / Q000139:chemically induced*
D018687:Antidepressive Agents, Second-Generation; D005473:Fluoxetine; D000525:Alprazolam