Comparison of acceleromyography and electromyography in vecuronium-induced neuromuscular blockade with xenon or sevoflurane anesthesia.
OBJECTIVE
To compare acceleromyography (AMG) and electromyography (EMG) with xenon or sevoflurane anesthesia during vecuronium-induced neuromuscular blockade.


METHODS
Prospective randomized study.


METHODS
University hospital.


METHODS
28 ASA physical status I and II adult patients presenting for elective surgery.


METHODS
Patients received vecuronium for neuromuscular blockade and either xenon (n = 11) or sevoflurane (n = 17) anesthesia.


RESULTS
The first twitch depression, which was expressed as a ratio of the first twitch to that obtained before the blocking drug was administered (T1/Tc), was measured simultaneously by AMG and EMG. T1/Tc as measured by AMG consistently demonstrated greater depression than that by EMG during recovery. The limits of agreement were unacceptably wide, suggesting that T1/Tc obtained by AMG is a poor predictor of T1/Tc as measured by EMG. Such relations were not affected by the anesthetic (xenon or sevoflurane) used.


CONCLUSIONS
AMG and EMG-cannot be used interchangeably with either xenon or sevoflurane anesthesia.
Nakata
Y
Y
Department of Anesthesia, Teikyo University School of Medicine and Ichihara Hospital, Chiba, Japan.
Goto
T
T
Saito
H
H
Ichinose
F
F
Uezono
S
S
Suwa
K
K
Morita
S
S
D000054:Acceleration; D000328:Adult; D000704:Analysis of Variance; D000762:Anesthesia Recovery Period; D000769:Anesthesia, Inhalation; D018685:Anesthetics, Inhalation / Q000008:administration & dosage*; D017558:Elective Surgical Procedures; D004576:Electromyography / Q000187:drug effects*; D005260:Female; D005544:Forecasting; D006801:Humans; D008297:Male; D008738:Methyl Ethers / Q000008:administration & dosage*; D009119:Muscle Contraction / Q000187:drug effects*; D019148:Neuromuscular Blockade; D003473:Neuromuscular Nondepolarizing Agents / Q000008:administration & dosage*; D011446:Prospective Studies; D000077149:Sevoflurane; D014673:Vecuronium Bromide / Q000008:administration & dosage*; D014978:Xenon / Q000008:administration & dosage*
D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D003473:Neuromuscular Nondepolarizing Agents; D000077149:Sevoflurane; D014978:Xenon; D014673:Vecuronium Bromide