[The histopathologic picture of experimental poisoning with ethylmethacrylates].
Toxic effect of hydroxyethylmethacrylate, acetoxyethylmethacrylate and diethylenglycomethacrylate were studied in rats surviving as long as 1 to 20 days after intramuscular administration. Conspicuous lesion were found only in calf muscles at the site of application. Muscle fibre necroses with inflammatory reaction occurred repeatedly in animals surviving 1-2 days. Newly formed connective tissue replacing impaired muscle fibres was found in rats surviving 5 days. Intoxication related other lesion in rat organs were not identified.
Nádvorník
F
F
Ustav soudního lékarství VFN a 1. LF UK, Praha.
Schneiderka
P
P
Roosová
M
M
Vacík
J
J
Labský
J
J
D000818:Animals; D005260:Female; D008689:Methacrylates / Q000633:toxicity*; D018482:Muscle, Skeletal / Q000187:drug effects / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar
D008689:Methacrylates
Histopatologický obraz experimentální intoxikace ethylmethakryláty.