title: Comparison of acceleromyography and electromyography in vecuronium-induced neuromuscular blockade with xenon or sevoflurane anesthesia.
abstract: OBJECTIVE
  To compare acceleromyography (AMG) and electromyography (EMG) with xenon or sevoflurane anesthesia during vecuronium-induced neuromuscular blockade.
  
  
  METHODS
  Prospective randomized study.
  
  
  METHODS
  University hospital.
  
  
  METHODS
  28 ASA physical status I and II adult patients presenting for elective surgery.
  
  
  METHODS
  Patients received vecuronium for neuromuscular blockade and either xenon (n = 11) or sevoflurane (n = 17) anesthesia.
  
  
  RESULTS
  The first twitch depression, which was expressed as a ratio of the first twitch to that obtained before the blocking drug was administered (T1/Tc), was measured simultaneously by AMG and EMG. T1/Tc as measured by AMG consistently demonstrated greater depression than that by EMG during recovery. The limits of agreement were unacceptably wide, suggesting that T1/Tc obtained by AMG is a poor predictor of T1/Tc as measured by EMG. Such relations were not affected by the anesthetic (xenon or sevoflurane) used.
  
  
  CONCLUSIONS
  AMG and EMG-cannot be used interchangeably with either xenon or sevoflurane anesthesia.
authors.affiliation: Department of Anesthesia, Teikyo University School of Medicine and Ichihara Hospital, Chiba, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Nakata
authors.forename: T
authors.initials: T
authors.lastname: Goto
authors.forename: H
authors.initials: H
authors.lastname: Saito
authors.forename: F
authors.initials: F
authors.lastname: Ichinose
authors.forename: S
authors.initials: S
authors.lastname: Uezono
authors.forename: K
authors.initials: K
authors.lastname: Suwa
authors.forename: S
authors.initials: S
authors.lastname: Morita
mesh_terms: D000054:Acceleration; D000328:Adult; D000704:Analysis of Variance; D000762:Anesthesia Recovery Period; D000769:Anesthesia, Inhalation; D018685:Anesthetics, Inhalation / Q000008:administration & dosage*; D017558:Elective Surgical Procedures; D004576:Electromyography / Q000187:drug effects*; D005260:Female; D005544:Forecasting; D006801:Humans; D008297:Male; D008738:Methyl Ethers / Q000008:administration & dosage*; D009119:Muscle Contraction / Q000187:drug effects*; D019148:Neuromuscular Blockade; D003473:Neuromuscular Nondepolarizing Agents / Q000008:administration & dosage*; D011446:Prospective Studies; D000077149:Sevoflurane; D014673:Vecuronium Bromide / Q000008:administration & dosage*; D014978:Xenon / Q000008:administration & dosage*
chemical_list: D018685:Anesthetics, Inhalation; D008738:Methyl Ethers; D003473:Neuromuscular Nondepolarizing Agents; D000077149:Sevoflurane; D014978:Xenon; D014673:Vecuronium Bromide