[Enhancement of epidermal regeneration by recombinant vaccinia virus growth factor].
Examining the specific activity has showed that recombinant vaccinia virus growth factor binds to appropriate receptors on the A-431 cell surface and prompts the healing acceleration of degree III burns in rats. This recombinant factor did not demonstrate pyrogenicity or toxicogenicity in tests on rabbits, guinea-pits, noninbred albino mice.
Petrov
V S
VS
Cheshenko
I O
IO
Omigov
V V
VV
Azaev
M Sh
MSh
Krendel'shchikov
A V
AV
Ovechkina
L G
LG
Cheshenko
N V
NV
Malygin
E G
EG
D000818:Animals; D002056:Burns / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D002478:Cells, Cultured; D004817:Epidermis / Q000187:drug effects / Q000502:physiology* / Q000648:ultrastructure; D005260:Female; D005500:Follow-Up Studies; D006133:Growth Substances / Q000627:therapeutic use*; D006168:Guinea Pigs; D051379:Mice; D016253:Microscopy, Immunoelectron; D011817:Rabbits; D051381:Rats; D011994:Recombinant Proteins; D016896:Treatment Outcome; D014616:Vaccinia virus / Q000378:metabolism*; D014945:Wound Healing / Q000187:drug effects / Q000502:physiology*
D006133:Growth Substances; D011994:Recombinant Proteins
Usilenie épidermal'noĭ regeneratsii s pomoshch'iu rekombinantnogo faktora rosta virusa ospovaktsiny.