title: Bone lesion in a patient with transplanted liver for a metastatic carcinoid. The role of somatostatin receptor scintigraphy.
abstract: A patient who had previously undergone ileal resection and liver transplantation for a gastroenteropancreatic (GEP) tumor was evaluated with somatostatin receptor scintigraphy (SRS) using 111In-DTPA-D-Phe1-pentetreotide. Eighteen months after surgery, during follow-up procedures, conventional imaging techniques (ultrasound, computed tomography, magnetic resonance imaging) only showed a relapse in the gastropancreatic lymph nodes, while SRS demonstrated skeletal spread. This case report emphasizes the clinical impact of SRS on the management of patients affected by neuroendocrine gastroenteropancreatic tumors.
authors.affiliation: Nuclear Medicine Department, Istituto Nazionale per la Cura e lo Studio dei Tumori, Milan, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Savelli
authors.forename: A
authors.initials: A
authors.lastname: Chiti
authors.forename: A
authors.initials: A
authors.lastname: Spinelli
authors.forename: E
authors.initials: E
authors.lastname: Regalia
authors.forename: V
authors.initials: V
authors.lastname: Mazzaferro
authors.forename: M R
authors.initials: MR
authors.lastname: Castellani
authors.forename: L
authors.initials: L
authors.lastname: Balzarini
authors.forename: R
authors.initials: R
authors.lastname: Musumeci
authors.forename: E
authors.initials: E
authors.lastname: Bombardieri
mesh_terms: D000293:Adolescent; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000556:secondary*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D007205:Indium Radioisotopes; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism / Q000556:secondary* / Q000601:surgery*; D016031:Liver Transplantation; D008303:Malignant Carcinoid Syndrome / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology* / Q000601:surgery*; D004369:Pentetic Acid; D017481:Receptors, Somatostatin / Q000378:metabolism*; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods
chemical_list: D007205:Indium Radioisotopes; D017481:Receptors, Somatostatin; D004369:Pentetic Acid