Hepatocyte nuclear factor 1alpha coding mutations are an uncommon contributor to early-onset type 2 diabetes in Ashkenazi Jews.
Behn
P S
PS
Division of Metabolism, Endocrinology and Diabetes, Washington University Medical School, St. Louis, Missouri 63110, USA.
Wasson
J
J
Chayen
S
S
Smolovitch
I
I
Thomas
J
J
Glaser
B
B
Permutt
M A
MA
D000328:Adult; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D004247:DNA / Q000097:blood; D004268:DNA-Binding Proteins / Q000235:genetics; D003924:Diabetes Mellitus, Type 2 / Q000235:genetics*; D005061:Europe, Eastern / Q000208:ethnology; D005091:Exons; D014644:Genetic Variation; D051537:Hepatocyte Nuclear Factor 1; D051538:Hepatocyte Nuclear Factor 1-alpha; D051539:Hepatocyte Nuclear Factor 1-beta; D006801:Humans; D007557:Israel; D007585:Jews / Q000235:genetics*; D008875:Middle Aged; D009687:Nuclear Proteins; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D014157:Transcription Factors / Q000096:biosynthesis / Q000235:genetics*
D004268:DNA-Binding Proteins; C496487:HNF1A protein, human; C496495:HNF1B protein, human; D051538:Hepatocyte Nuclear Factor 1-alpha; D009687:Nuclear Proteins; D014157:Transcription Factors; D051537:Hepatocyte Nuclear Factor 1; D051539:Hepatocyte Nuclear Factor 1-beta; D004247:DNA