Attachment of gelatin films to tissue using argon beam coagulator.
Cross-linked gelatin films were bonded to heart muscle and to lung pleura and parenchyma using the electrical discharge of an argon beam radiofrequency coagulator. The bonds were stable in warm saline buffer for minutes to hours. Bonding was thought to partly occur through a mechanical interlock of film and tissue elements. The interdigitation of tissue and film arose during exposure to the argon beam, which denatured protein constituents of both, and created a fluidized state that rapidly coalesced.
Dapper
G
G
Point Biomedical Systems, San Carlos, California 94070, USA.
Wallace
D G
DG
Yamamoto
R
R
Barrett
S
S
Ly
D
D
Nguyen
M
M
Moravcsik
P
P
Lifrieri
J
J
Tran
H
H
Reich
C
C
Sawyer
P N
PN
D000818:Animals; D001128:Argon; D001672:Biocompatible Materials / Q000737:chemistry*; D002152:Calorimetry, Differential Scanning; D003094:Collagen / Q000737:chemistry; D004564:Electrocoagulation / Q000379:methods*; D005780:Gelatin / Q000737:chemistry*; D009206:Myocardium; D010994:Pleura; D013552:Swine; D013718:Tensile Strength
D001672:Biocompatible Materials; D001128:Argon; D005780:Gelatin; D003094:Collagen