Multiple-domain dissociation between impaired visual perception and preserved mental imagery in a patient with bilateral extrastriate lesions.
A brain-damaged patient is described whose pattern of performance provides insight into both the functional mechanisms and the neural structures involved in visual mental imagery. The patient became severely agnosic, alexic, achromatopsic and prosopagnosic following bilateral brain lesions in the temporo-occipital cortex. However, her mental imagery for the same visual entities that she could not perceive was perfectly preserved. This clear-cut dissociation held across all the major domains of high-level vision: object recognition, reading, colour and face processing. Our findings, together with other reports on domain-specific dissociations and functional brain imaging studies, provide evidence to support the view that visual perception and visual mental imagery are subserved by independent functional mechanisms, which do not share the same cortical implementation. In particular, our results suggest that mental imagery abilities need not be mediated by early visual cortices.
Bartolomeo
P
P
INSERM Unit 324, Centre Paul Broca, Paris, France. paolo@broca.inserm.fr
Bachoud-Lévi
A C
AC
De Gelder
B
B
Denes
G
G
Dalla Barba
G
G
Brugières
P
P
Degos
J D
JD
D000368:Aged; D000377:Agnosia / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D002561:Cerebrovascular Disorders / Q000150:complications / Q000473:pathology / Q000503:physiopathology*; D003118:Color Perception; D004411:Dyslexia, Acquired / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D005260:Female; D005556:Form Perception; D006801:Humans; D007092:Imagination; D008279:Magnetic Resonance Imaging; D009778:Occipital Lobe / Q000473:pathology / Q000503:physiopathology; D013702:Temporal Lobe / Q000473:pathology / Q000503:physiopathology; D014796:Visual Perception