Ki-1 lymphoma with cardiac involvement at initial presentation.
Anaplastic large cell lymphoma is a rare malignancy in childhood. We describe the case of a 6-year-old boy with Ki-1 lymphoma of the thymus who presented with an endocardiac mass. The first histologic analysis suggested a high-grade undifferentiated sarcoma, but reevaluation and immunohistochemistry confirmed the CD30+ lymphoid derivation of the process. The patient was given chemotherapy and 24 months later he remains in complete remission. It is noted that echocardiography was repeated many times to detect heart lesion.
Papadopoulou
A L
AL
First Department of Pediatrics, University of Athens, Aghia Sophia Children's Hospital, Greece.
Argiriou
M
M
Bonoris
M
M
Papadopoulos
G S
GS
Van Vliet-Constantinidou
C
C
Stavrinadis
C
C
Moschovi
M
M
Tzortzatou-Stathopoulou
F
F
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002648:Child; D006338:Heart Neoplasms / Q000188:drug therapy* / Q000503:physiopathology* / Q000601:surgery*; D006801:Humans; D017728:Lymphoma, Large-Cell, Anaplastic / Q000188:drug therapy* / Q000503:physiopathology* / Q000601:surgery*; D008297:Male; D012074:Remission Induction