title: [Determination of the end-point of naproxen sodium granules in Glatt VG-WS-CD high-shear granulator fluid bed dryer equipment].
abstract: Determination of the end-point of granulation in the Glatt VG-600-WS-CD-120 high shear granulator-fluid dryer is presented. The method of the determination based on measuring of the impeller motor current during the granulation operation. The influencing parameters during the granulation of naproxen-sodium on granule-quality are also shown. Reproductibility of the acceptable granule-quality in serial producing is documented.
authors.affiliation: Alkaloida Vegyészeti Gyár Rt., Tiszavasvári.
authors.forename: B Z
authors.initials: BZ
authors.lastname: Jekóné
authors.forename: K E
authors.initials: KE
authors.lastname: Görgeyné
mesh_terms: D002626:Chemistry, Pharmaceutical / Q000295:instrumentation* / Q000379:methods; D004304:Dosage Forms; D009288:Naproxen / Q000737:chemistry*; D015203:Reproducibility of Results
chemical_list: D004304:Dosage Forms; D009288:Naproxen
vernacular_title: Naproxen-nátrium granulálálás végpontijának megállapítása a Glatt VG-WS-CD berendezésben.