title: [Color-coded signal-enhanced duplex ultrasonography of space-occupying intramammary processes].
abstract: OBJECTIVE
  Prospective comparison of plain and signal-enhanced frequency and amplitude-modulated colour Doppler ultrasound of intramammary tumours to evaluate new criteria for diagnostic analysis.
  
  
  METHODS
  Frequency and amplitude-modulated colour Doppler examination with qualitative and quantitative analysis of 80 potentially malignant intramammary lesions were performed before and after application of d-galactose.
  
  
  RESULTS
  Signal-enhanced sonography revealed a typical vessel morphology of primary and recurrent breast cancer facilitating differential diagnosis. In 18 (frequency modulated US) or 16 (amplitude modulated US) of 51 carcinomas, the typical malignant vascularisation structure was sufficiently visible only after application of the signal enhancing agent. In 50% of the fibroadenomas, Doppler analysis of the vessels was possible only after application of d-galactose.
  
  
  CONCLUSIONS
  The application of d-galactose provides additional criteria for the differential diagnosis of breast lesions due to improved visualisation of the vascularisation structure.
authors.affiliation: Strahlenklinik und Poliklinik, Virchow-Klinikum, Medizinische Fakultät Humboldt-Universität zu Berlin.
authors.forename: R J
authors.initials: RJ
authors.lastname: Schröder
authors.forename: J
authors.initials: J
authors.lastname: Hadijuana
authors.forename: N
authors.initials: N
authors.lastname: Hidajat
authors.forename: J
authors.initials: J
authors.lastname: Mäurer
authors.forename: S
authors.initials: S
authors.lastname: Venz
authors.forename: T
authors.initials: T
authors.lastname: Vogl
authors.forename: S
authors.initials: S
authors.lastname: Weber
authors.forename: R
authors.initials: R
authors.lastname: Felix
mesh_terms: D000328:Adult; D000368:Aged; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D002277:Carcinoma / Q000000981:diagnostic imaging*; D003287:Contrast Media; D003937:Diagnosis, Differential; D005069:Evaluation Studies as Topic; D005260:Female; D018226:Fibroadenoma / Q000000981:diagnostic imaging*; D006801:Humans; D008875:Middle Aged; D011134:Polysaccharides; D011446:Prospective Studies; D018615:Ultrasonography, Doppler, Color
chemical_list: D003287:Contrast Media; D011134:Polysaccharides; C059891:SHU 508
vernacular_title: Farbkodierte signalverstärkte Duplexsonographie raumfordernder intramammärer Prozesse.