title: The contribution of 18F-fluoro-2-deoxy-glucose positron emission tomographic imaging to radiotherapy planning in lung cancer.
abstract: A retrospective analysis was performed to determine whether coronal thoracic [18F]fluoro-2-deoxy-glucose positron emission tomography (FDG-PET) scans, if viewed at the time of radiotherapy (RT) planning, would have influenced the anterior-posterior (AP) RT volumes that were administered to a group of unoperated lung cancer patients. Viewing of PET and diagnostic images enabled a qualitative assessment of whether abnormal thoracic PET activity was present in areas regarded as normal by diagnostic imaging; this would, therefore, have influenced the RT volume if done prospectively. Additionally a method of graphical co-registration was devised to quantitate the adequacy of coverage of each patient's abnormal PET activity by his/her actual RT field. Of 15 patients analyzed, 26.7% (four patients) would have had their RT volume influenced by PET findings, highlighting the potential value of PET in treatment planning.
authors.affiliation: Radiotherapy Centre, Austin and Repatriation Medical Centre, West Heidleberg, Victoria, Australia.
authors.forename: J D
authors.initials: JD
authors.lastname: Kiffer
authors.forename: S U
authors.initials: SU
authors.lastname: Berlangieri
authors.forename: A M
authors.initials: AM
authors.lastname: Scott
authors.forename: G
authors.initials: G
authors.lastname: Quong
authors.forename: M
authors.initials: M
authors.lastname: Feigen
authors.forename: W
authors.initials: W
authors.lastname: Schumer
authors.forename: C P
authors.initials: CP
authors.lastname: Clarke
authors.forename: S R
authors.initials: SR
authors.lastname: Knight
authors.forename: F J
authors.initials: FJ
authors.lastname: Daniel
mesh_terms: D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy*; D011880:Radiotherapy Planning, Computer-Assisted; D012189:Retrospective Studies; D014055:Tomography, Emission-Computed
chemical_list: D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18