title: [The development of a method for viral inactivation using thiophosphamide].
abstract: Using three-functional alkylating compound thiophosphamide complete inactivation of the influenza and herpesviruses of type 1 and 2 was achieved. The method provides full inactivation of DNA- and RNA-containing viruses and preservation of their immunogenic properties.
authors.affiliation: Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, Kyiv.
authors.forename: A D
authors.initials: AD
authors.lastname: Shved
authors.forename: O E
authors.initials: OE
authors.lastname: Kitam
authors.forename: H S
authors.initials: HS
authors.lastname: Skrypchenko
authors.forename: S S
authors.initials: SS
authors.lastname: Tokolova
mesh_terms: D000477:Alkylating Agents / Q000494:pharmacology*; D000818:Animals; D000998:Antiviral Agents / Q000494:pharmacology*; D002478:Cells, Cultured; D002642:Chick Embryo; D003864:Depression, Chemical; D018259:Herpesvirus 1, Human / Q000187:drug effects* / Q000276:immunology; D009980:Influenza A virus / Q000187:drug effects* / Q000276:immunology; D007252:Influenza Vaccines; D013852:Thiotepa / Q000494:pharmacology*; D015164:Vaccines, Inactivated; D014765:Viral Vaccines; D014776:Virus Cultivation
chemical_list: D000477:Alkylating Agents; D000998:Antiviral Agents; D007252:Influenza Vaccines; D015164:Vaccines, Inactivated; D014765:Viral Vaccines; D013852:Thiotepa
vernacular_title: Rozrobka sposobu inaktyvatsiï virusiv za dopomohoiu tiofosfamidu.