[The use of neoadjuvant selective intra-arterial polychemotherapy and its modifier verapamil in the combined treatment of colorectal cancer].
After combined treatment of 74 patients for colorectal cancer using preoperative neoadjuvant intraarterial selective polychemotherapy (IAPCT) three-year survival index have constituted (77.0 +/- 5.2)%, the cancer recurrence have occurred in (10.8 +/- 2.8)%, distant metastases were revealed in (17.5 +/- 4.2)%. Using verapamil as a IAPCT modifier in 54 patient three-year survival have increased by 11.8%, the frequency of distant metastases occurrence have reduced by 10.1%.
Kikot'
V A
VA
Sorokin
B V
BV
Iugrinov
O G
OG
Galakhin
K A
KA
Braun
E M
EM
Lishchishina
E M
EM
Priĭmak
V V
VV
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D017024:Chemotherapy, Adjuvant; D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000601:surgery; D006801:Humans; D007261:Infusions, Intra-Arterial / Q000009:adverse effects / Q000379:methods; D011300:Preoperative Care / Q000379:methods; D014665:Vasodilator Agents / Q000008:administration & dosage*; D014700:Verapamil / Q000008:administration & dosage*
D014665:Vasodilator Agents; D014700:Verapamil
Primenenie neoad'iuvantnoĭ selektivnoĭ vnutriarterial'noĭ polikhimioterapii i ee modifikatora verapamila v kombinirovannom lechenii kolorektal'nogo raka.