title: Methods to obtain quantitative parametric descriptions of the optical surfaces of the human crystalline lens from Scheimpflug slit-lamp images. I. Image processing methods.
abstract: Of the methods developed (e.g., phakometry, magnetic resonance imaging, etc.) for noninvasive measurement of the geometry of the anterior segment of the human eye, Scheimpflug photography offers the best resolution and the highest precision. The primary obstacle encountered with this or any other image-based method has been in obtaining quantitative measurements directly from the images. Image enhancement (gray-scale gradient analysis) and pattern recognition methods (Hough transform and recursive least-squares algorithms) are developed so that parametric representations of lens surfaces and zone boundaries can be obtained directly from the images. Methods to correct for nonlinear Scheimpflug camera reproduction ratios and provide error estimates for geometrical parameters are also developed and will be presented separately. Combined, these techniques yield representations of lens geometry having sufficient precision, to which paraxial ray tracing can be applied to determine lens optical properties by using well-posed optical models with one unknown.
authors.affiliation: Cytometrics, Inc., Philadelphia, Pennsylvania 19106, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Cook
authors.forename: J F
authors.initials: JF
authors.lastname: Koretz
mesh_terms: D000465:Algorithms; D006801:Humans; D007089:Image Enhancement; D007091:Image Processing, Computer-Assisted; D007908:Lens, Crystalline / Q000473:pathology*; D008433:Mathematics; D008953:Models, Anatomic; D009885:Ophthalmology / Q000295:instrumentation* / Q000379:methods*; D010781:Photography / Q000295:instrumentation* / Q000379:methods*