A review of the literature: transmyocardial laser revascularization.
OBJECTIVE
Transmyocardial laser revascularization is an investigational procedure that improves chronic angina that is not amenable to other forms of therapy. The theorized mechanism is an increased supply of oxygenated blood to the myocardium via the creation of left ventricular transmural channels. The objective of this review is to facilitate an understanding of the current work published in the literature on the subject of transmyocardial laser revascularization.


METHODS
Using Melvyl Medline, all pertinent literature associated with transmyocardial laser revascularization was sought and reviewed.


CONCLUSIONS
The research in transmyocardial laser revascularization is growing. The results of the current work in animals is conflicting with some showing a benefit from this procedure and others that refute its effectiveness. This may be the outcome of differing methodology, which has yet to be evaluated. Although the results of human trials are positive, the overall effectiveness in comparison with the conventional forms of therapy has not been addressed. It is, therefore, a procedure worthy of continued study.
Hussain
F M
FM
Department of Vascular Surgery, Harbor UCLA Medical Center, Torrance 90502, USA.
Heilbron
M
M
D000787:Angina Pectoris / Q000601:surgery; D016342:Angioplasty, Laser; D000818:Animals; D002245:Carbon Dioxide; D006695:Holmium; D006801:Humans; D017202:Myocardial Ischemia / Q000601:surgery*; D009204:Myocardial Revascularization / Q000379:methods*; D018919:Neovascularization, Physiologic
D002245:Carbon Dioxide; D006695:Holmium