Analysis of oxyhalides in water by ion chromatography-ionspray mass spectrometry.
A sensitive method for analyzing chlorite, chlorate, bromate and iodate in water by ion chromatography (IC) coupled with ionspray tandem mass spectrometry (IS-MS-MS) has been developed. Prior to analysis, samples were subjected to off-line sample clean-up with Ba, Ag and H-form resins to remove sulfate, chloride and hydrogencarbonate, respectively. Oxyhalides in the purified samples were concentrated and separated on a short, high-performance anion-exchange column. An eluent consisting of ammonium nitrate in methanol-water (9:1, v/v) was found to be suitable for separating the analytes, while providing enhanced detector sensitivity. The coupling of IC with IS-MS-MS allows for the identification of the four oxyhalides mentioned above in a single run with very high specificity and sensitivity.
Charles
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L
Institut Louise Blanquet, Facultés de Médecine et de Pharmacie, Clermont-Ferrand, France.
Pépin
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D004326:Drinking; D006219:Halogens / Q000032:analysis* / Q000737:chemistry; D013058:Mass Spectrometry / Q000379:methods*; D000432:Methanol / Q000737:chemistry; D012680:Sensitivity and Specificity; D014867:Water / Q000737:chemistry*
D006219:Halogens; D014867:Water; D000432:Methanol