[The participation of the dorsal hippocampus in the antianxiety action of melatonin and diazepam].
The pineal hormone melatonin and the tranquilizer diazepam given in an equal dose (0.1 mg/kg) demonstrated an anxiolytic effect on a model of a conflict situation in rats. Damage to the dorsal hippocampus produced a similar effect and the anxiolytic activity of the drugs under study was removed against this background.
Arushanian
E B
EB
Department of Pharmacology, Stavropol Medical Academy, Russia.
Beĭer
E V
EV
D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001522:Behavior, Animal / Q000187:drug effects; D003220:Conflict, Psychological; D003975:Diazepam / Q000494:pharmacology*; D006624:Hippocampus / Q000502:physiology* / Q000601:surgery; D008297:Male; D008550:Melatonin / Q000494:pharmacology*; D051381:Rats
D014151:Anti-Anxiety Agents; D008550:Melatonin; D003975:Diazepam
Uchastie dorsal'nogo gippokampa v protivotrevozhnom deĭstvii melatonina i diazepama.