title: Drug-induced systemic lupus erythematosus after 8 years of treatment with carbamazepine.
abstract: This is the report of a late-onset carbamazepine-induced systemic lupus erythematosus in a 34-year-old patient who had been treated with daily carbamazepine for 8 years because of complex partial seizures. When carbamazepine was discontinued, symptoms rapidly improved and antinuclear antibodies disappeared. So far, few cases have been reported of carbamazepine-induced lupus erythematosus within months after the start of treatment. This is the first case report about carbamazepine-induced systemic lupus erythematosus with serological confirmation after years of treatment without side effects.
authors.affiliation: Friedrich-Baur-Institut, Medizinische Kunik, Klinikum Innenstadt, Ludwig-Maximillians-Universität, Munich, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Toepfer
authors.forename: T
authors.initials: T
authors.lastname: Sitter
authors.forename: H
authors.initials: H
authors.lastname: Lochmüller
authors.forename: D
authors.initials: D
authors.lastname: Pongratz
authors.forename: W
authors.initials: W
authors.lastname: Müller-Felber
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects* / Q000097:blood; D002220:Carbamazepine / Q000009:adverse effects* / Q000097:blood; D004828:Epilepsies, Partial / Q000188:drug therapy; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000139:chemically induced*; D008297:Male
chemical_list: D000927:Anticonvulsants; D002220:Carbamazepine