[Effectiveness of differential diagnosis of benign and malignant ulcers at endoscopy].
OBJECTIVE
Assessment of efficacy of differential diagnosis between benign and malignant lesions in gastric mucosa by means of endoscopy.


METHODS
Morphological verdicts upon investigation of operative specimens were compared to findings at preoperative duodenofibrogastroscopy with spot biopsy in 326 patients operated for gastric ulcer. The number of discrepancies between the endoscopic and morphological diagnoses enabled estimation of endoscopy + biopsy efficiency in identification of the ulcer malignancy.


RESULTS
The number of diagnostic errors made on malignant or benign nature of ulcer at endoscopic and biopsy investigations is rather big, i.e. at least 12% for both false negative and false positive hypophyses. The overall diagnostic efficacy of endoscopy in detection of the disease lies within 65-80%.


CONCLUSIONS
Reliability of endoscopic identification including biopsy of malignant nature of gastric ulcers is not very high. Real sensitivity of this method in detection of ulcers undergoing malignant transformation reaches 76-78%.
Gurin
N N
NN
Logunov
K V
KV
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001706:Biopsy; D002908:Chronic Disease; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D016145:Endoscopy, Digestive System; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000601:surgery; D013276:Stomach Ulcer / Q000175:diagnosis* / Q000601:surgery
Effektivnost' differentsial'noĭ diagnostiki dobrokachestvennykh i rakovykh iazv zheludka pri éndoskopii.