Signature sequences in diverse proteins provide evidence of a close evolutionary relationship between the Deinococcus-thermus group and cyanobacteria.
A number of proteins have been identified that contain prominent sequence signatures that are uniquely shared by the members of the Deinococcus-Thermus genera and the cyanobacterial species but which are not found in any of the other eubacterial or archaebacterial homologs. The proteins containing such sequence signatures include (1) the DnaJ/Hsp40 family of proteins, (2) DNA polymerase I, (3) the protein synthesis elongation factor EF-Tu, and (4) the elongation factor EF-Ts. A strong affinity of the Deinococcus-Thermus species to cyanobacteria is also seen in the phylogenetic trees based on Hsp70 and DnaJ sequences. These results provide strong evidence of a close and specific evolutionary relationship between species belonging to these two eubacterial divisions.
Gupta
R S
RS
Department of Biochemistry, McMaster University, Hamilton, Ontario, Canada L8N 3Z5.
Johari
V
V
D000595:Amino Acid Sequence; D001426:Bacterial Proteins / Q000235:genetics*; D000458:Cyanobacteria / Q000235:genetics*; D019143:Evolution, Molecular; D006095:Gram-Positive Cocci / Q000235:genetics*; D008969:Molecular Sequence Data; D010446:Peptide Fragments / Q000235:genetics*; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity; D013824:Thermus / Q000235:genetics*
D001426:Bacterial Proteins; D010446:Peptide Fragments