title: [The use of the new biological adhesive preparation fibrin polymer in thyroid surgery].
abstract: A study made in 18 patients with nodular euthyroiditis and toxic goiter proved high efficacy of a new preparation "Fibrin Polymer" ("Bioadhesive") based on a combined action of human fibrinogen and thrombin. Employment of the above preparation makes for maintaining intraoperative hemostasis, reducing postoperative wound serous and haemorrhagic and lymphatic secretion, joining lips of skin wound to improve cosmetic results of the operation. A novel modality is proposed for low-invasive treatment of cystic forms of nodular goiter based on obliteration of the cyst with the aid of the preparation "Fibrin Polymer" administered by puncturing the cyst following aspiration of its contents. Of the eight treated patients, 1 had a recurrence, 2 subjects had more than 2-fold diminution in cyst size, 5 patients recovered 12 months following the treatment. The preparation "Fibrin Polymer" should, we believe, come to be widely used in thyroid surgery.
authors.forename: S M
authors.initials: SM
authors.lastname: Cheren'ko
mesh_terms: D000328:Adult; D004341:Drug Evaluation; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D006044:Goiter, Nodular / Q000601:surgery; D006111:Graves Disease / Q000601:surgery; D006488:Hemostasis, Surgical / Q000379:methods; D006490:Hemostatics / Q000627:therapeutic use*; D006801:Humans; D019106:Postoperative Hemorrhage / Q000517:prevention & control; D013961:Thyroid Gland / Q000601:surgery*; D013965:Thyroidectomy
chemical_list: D015718:Fibrin Tissue Adhesive; D006490:Hemostatics
vernacular_title: Zastosuvannia novoho biolohichnoho adhezyvnoho preparatu "Polimer fibrynu" v khirurhiï shchytovydnoï zalozy.