title: Acquired perforating dermatosis and diabetic nephropathy--a case report and review of the literature.
abstract: A case of acquired perforating dermatosis associated with diabetic nephropathy is described. The case is unusual in that the dermatosis first developed approximately 1 year after renal transplantation rather than at a time when renal function was more severely impaired or during haemodialysis. There was a partial response to treatment with isotretinoin but the use of this drug was limited by the development of hyperlipidaemia. The relevant literature is reviewed.
authors.affiliation: Department of Dermatology, St. Albans City Hospital, UK.
authors.forename: P D
authors.initials: PD
authors.lastname: Maurice
authors.forename: G H
authors.initials: GH
authors.lastname: Neild
mesh_terms: D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000150:complications; D003928:Diabetic Nephropathies / Q000150:complications*; D006801:Humans; D006949:Hyperlipidemias / Q000139:chemically induced; D015474:Isotretinoin / Q000627:therapeutic use; D007641:Keratolytic Agents / Q000009:adverse effects / Q000627:therapeutic use; D007676:Kidney Failure, Chronic / Q000150:complications*; D008297:Male; D012871:Skin Diseases / Q000150:complications* / Q000188:drug therapy / Q000473:pathology
chemical_list: D007641:Keratolytic Agents; D015474:Isotretinoin