Different erythromycin resistance mechanisms in group C and group G streptococci.
Different mechanisms of erythromycin resistance predominate in group C and G streptococcus (GCS and GGS, respectively) isolates collected from 1992 to 1995 in Finland. Of the 21 erythromycin-resistant GCS and 32 erythromycin-resistant GGS isolates, 95% had the mefA or mefE drug efflux gene and 94% had the ermTR methylase gene, respectively.
Kataja
J
J
Antimicrobial Research Laboratory, National Public Health Institute, Turku, Finland. janne.kataja@utu.fi
Seppälä
H
H
Skurnik
M
M
Sarkkinen
H
H
Huovinen
P
P
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001426:Bacterial Proteins; D004352:Drug Resistance, Microbial / Q000235:genetics; D004917:Erythromycin / Q000494:pharmacology*; D008780:Methyltransferases / Q000235:genetics; D010641:Phenotype; D013291:Streptococcus / Q000187:drug effects*
D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D004917:Erythromycin; C111078:ErmTR protein, bacteria; D008780:Methyltransferases