Recombination at work for meiosis.
In sexually reproducing organisms, homologous recombination increases genetic diversity in gametes and ensures proper chromosome segregation. Recent publications have provided details of the molecular intermediates and proteins involved, the control of the distribution of recombination events at the chromosomal level, and the surveillance mechanisms that coordinate recombination with the meiotic cell cycle.
Smith
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KN
Institut Curie, Section de Recherche, CNRS UMR144, Paris, France.
Nicolas
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A
D000782:Aneuploidy; D000818:Animals; D003434:Crossing Over, Genetic; D004249:DNA Damage; D004260:DNA Repair; D006801:Humans; D008540:Meiosis; D008957:Models, Genetic; D011995:Recombination, Genetic; D012441:Saccharomyces cerevisiae; D013698:Templates, Genetic