A fatal case of fungal endocarditis of the tricuspid valve associated with long-term venous catheterization and treatment with antibiotics in a patient with a history of alcohol abuse.
We report a fatal case of fungal (candidal) endocarditis of the tricuspid valve with clinico-pathologically interesting findings following and associated with candidal pneumonia during long-term central venous catheterization (CVC) for intravenous therapy and long-term treatment with antibiotics for bacterial and fungal infection in a patient with a history of alcohol abuse. We review the literature on fungal cardiac infection related to long-term catheterization and alcohol abuse, and discuss the pathogenesis.
Ohmori
T
T
Second Department of Pathology, Ehime University School of Medicine, Japan. ohmori@m.ehime-u.ac.jp
Iwakawa
K
K
Matsumoto
Y
Y
Arita
N
N
Okada
K
K
D000368:Aged; D000437:Alcoholism / Q000150:complications; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002177:Candidiasis / Q000188:drug therapy / Q000473:pathology; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D004696:Endocarditis / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D017809:Fatal Outcome; D006349:Heart Valve Diseases / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D014261:Tricuspid Valve / Q000382:microbiology*
D000900:Anti-Bacterial Agents