title: [Adrenal carcinoma. Clinical and anatomopathological prognostic factors].
abstract: We performed on 9 patients with adrenal cortical carcinoma a retrospective study during 1967-1995 to evaluate the most important prognostic factors. Four patients were males and five females (mean age: 40.3 years). Five patients had endocrine symptoms (55%) and four had "non-functioning" tumors (45%). The tumor involved the left adrenal gland in 5 cases and the right in 4. The mean diameter of the neoplasm was 9.5 cm, with a mean weight of 411 g. The average duration of symptoms before diagnosis was 7.3 months. One patient had invasion of the inferior vena cava with liver metastases. Eight patients underwent curative surgery, the median survival time was 13.7 months, only 1 patient is alive after 18 months from surgical resection. We concluded that adrenal carcinomas have poor prognosis; staging and grading of the neoplasm, and age of the patient at diagnosis are predictors of survival.
authors.affiliation: Istituto di Chirurgia Generale e Cardiovascolare, Università degli studi, Milano.
authors.forename: M
authors.initials: M
authors.lastname: Boneschi
authors.forename: M
authors.initials: M
authors.lastname: Erba
authors.forename: L
authors.initials: L
authors.lastname: Beretta
authors.forename: S
authors.initials: S
authors.lastname: Miani
authors.forename: E M
authors.initials: EM
authors.lastname: Bortolani
mesh_terms: D000293:Adolescent; D000302:Adrenal Cortex / Q000473:pathology; D000306:Adrenal Cortex Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018268:Adrenocortical Carcinoma / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D000328:Adult; D000367:Age Factors; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D013997:Time Factors
vernacular_title: I carcinomi del surrene. Fattori prognostici clinici ed anatomopatologici.