title: The comparison of primordial germ cell populations in embryos of KE and CBA inbred strains of mice.
abstract: The changes in primordial germ cell (PGC) populations were compared in embryos of two inbred strains of mice-KE and CBA/Kw on 11, 12, 13 and 14 day of foetal life. The number of PGCs did not differ in 11-day embryos of both strains. In 12-day CBA/Kw embryos the proliferation rate of PGCs was higher and the number of PGC was significantly higher than in 12-day KE embryos. However, on subsequent days the PGC proliferation rate decreased in CBA/Kw but rapidly increased in KE embryos, leading to significantly higher number of PGCs in 14-day KE embryos. These differences in proliferation rate between KE and CBA/Kw PGCs can be regarded as the reason of strong selection against CBA/Kw derived gametes observed in KE<-->CBA aggregation chimaeras.
authors.affiliation: Department of Genetics and Evolution, Jagiellonian University, Kraków, Poland.
authors.forename: B
authors.initials: B
authors.lastname: Wabik-Sliz
authors.forename: I
authors.initials: I
authors.lastname: Paczuska
authors.forename: A
authors.initials: A
authors.lastname: Wiśniewska
authors.forename: M
authors.initials: M
authors.lastname: Lenartowicz
mesh_terms: D000469:Alkaline Phosphatase / Q000032:analysis; D000818:Animals; D002452:Cell Count; D002455:Cell Division / Q000502:physiology; D002678:Chimera; D005314:Embryonic and Fetal Development; D005260:Female; D005854:Germ Cells / Q000166:cytology*; D006651:Histocytochemistry; D051379:Mice; D008815:Mice, Inbred Strains; D013234:Stem Cells / Q000166:cytology
chemical_list: D000469:Alkaline Phosphatase