Diagnosis and management of complicated gout.
Although a diagnosis of gout can be confirmed by the presence of monosodium urate crystals in synovial fluid, arriving at the suspected diagnosis and managing the disease can be a challenge for primary care physicians and specialists alike. Symptoms of gout can mimic other forms of inflammatory arthritis such as rheumatoid arthritis, pseudogout, or septic arthritis. Treatment can be complicated by the patient's need for drugs that contribute to hyperuricemia. Once other diagnoses are ruled out and urate crystals are detected under polarized light microscopy, treatment to end the acute attack and follow-up treatment designed to lower serum urate levels can be undertaken.
Wise
C M
CM
Division of Rheumatology, Allergy, and Immunology, Medical College of Virginia, Virginia Commonwealth University, Richmond, USA.
Agudelo
C A
CA
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D003078:Colchicine / Q000627:therapeutic use*; D006073:Gout / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D006074:Gout Suppressants / Q000627:therapeutic use*; D006801:Humans
D000894:Anti-Inflammatory Agents, Non-Steroidal; D006074:Gout Suppressants; D003078:Colchicine