title: Relation of left atrial spontaneous echo contrast with prethrombotic state in atrial fibrillation associated with systemic hypertension, idiopathic dilated cardiomyopathy, or no identifiable cause (lone).
abstract: To investigate the association of left atrial (LA) spontaneous echo contrast with the hemostatic state in nonrheumatic atrial fibrillation (AF), we examined the plasma levels of prothrombin fragment 1+2 and fibrinopeptide A in 73 patients with chronic nonrheumatic AF undergoing transesophageal echocardiography and 38 age-matched normal subjects. The results support the theory that LA spontaneous echo contrast in nonrheumatic AF is associated with a hypercoagulable state, especially in patients with marked LA spontaneous echo contrast.
authors.affiliation: Department of Internal Medicine, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan, Republic of China.
authors.forename: L M
authors.initials: LM
authors.lastname: Tsai
authors.forename: J H
authors.initials: JH
authors.lastname: Chen
authors.forename: C J
authors.initials: CJ
authors.lastname: Tsao
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001281:Atrial Fibrillation / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D002312:Cardiomyopathy, Hypertrophic / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D016022:Case-Control Studies; D017548:Echocardiography, Transesophageal; D005260:Female; D005344:Fibrinopeptide A / Q000378:metabolism*; D006325:Heart Atria / Q000000981:diagnostic imaging*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010446:Peptide Fragments / Q000378:metabolism*; D011498:Protein Precursors / Q000378:metabolism*; D011516:Prothrombin / Q000378:metabolism*; D013923:Thromboembolism / Q000517:prevention & control*
chemical_list: D010446:Peptide Fragments; D011498:Protein Precursors; D005344:Fibrinopeptide A; C029733:prothrombin fragment 1; C044183:prothrombin fragment 2; D011516:Prothrombin