title: A clinical evaluation of an allograft combined with a bioabsorbable membrane versus an alloplast/allograft composite graft combined with a bioabsorbable membrane. 100 consecutively treated cases.
abstract: The purpose of this study was to evaluate and compare the clinical effectiveness of 2 surgical techniques in treating periodontal defects. Both techniques involved tetracycline treatment of a root planed root, grafting the osseous defect with a bone graft, and placement of a bioabsorbable membrane. In group A, the bone graft was a mix of demineralized freeze-dried allograft, tetracycline, and porous hydroxyapatite and in group B, the bone graft was a mix of demineralized freeze-dried allograft and tetracycline. There was a statistically significant increase in recession (group A, 0.7 mm; group B, 0.6 mm), decreases in probing depth (group A, 6.1 mm; group B, 5.6 mm), and gains in attachment levels (group A, 5.4 mm; group B, 5.0 mm). There were no statistically significant differences between the results for either group. The defects associated with furcations and those that were not associated with furcations had similar results, except for the percent attachment gain. Smoking and age (> or =60 years old) could not be associated with results. Defects with > or =10 mm probing depths (PD) had greater PD reductions (group A, 7.7 mm; group B, 7.1) and attachment gains (group A, 6.6 mm; group B, 6.4 mm) than the defects with probing depths less than 10 mm (probing reduction group A, 4.8 mm; group B, 4.5 mm; attachment gain group A, 4.4 mm; group B, 4.0 mm). Both surgical procedures improved the clinical situation. However, neither technique seemed to offer a statistical advantage over the other. The inclusion of porous hydroxyapatite did not improve or diminish the results.
authors.forename: R J
authors.initials: RJ
authors.lastname: Harris
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D016301:Alveolar Bone Loss / Q000601:surgery; D000704:Analysis of Variance; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D001673:Biodegradation, Environmental; D001861:Bone Regeneration / Q000187:drug effects*; D016025:Bone Transplantation / Q000379:methods*; D003648:Decalcification Technique; D017886:Durapatite / Q000494:pharmacology*; D005260:Female; D005612:Freeze Drying; D017823:Furcation Defects / Q000601:surgery; D005889:Gingival Recession / Q000601:surgery; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D006801:Humans; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D017622:Periodontal Attachment Loss / Q000601:surgery; D010510:Periodontal Diseases / Q000601:surgery*; D010512:Periodontal Index; D012907:Smoking; D013752:Tetracycline / Q000008:administration & dosage; D014092:Tooth Root / Q000187:drug effects; D014182:Transplantation, Autologous; D014184:Transplantation, Homologous
chemical_list: D000900:Anti-Bacterial Agents; D008567:Membranes, Artificial; D017886:Durapatite; D013752:Tetracycline