Hormone replacement therapy and breast cancer.
Hormone replacement therapy (HRT) leads to a similar annual increase in risk of breast cancer as does each extra year of remaining premenopausal. Taken for more than 10 years HRT leads to a 35% increase in risk of developing breast cancer. It does not increase a woman's risk of dying of breast cancer, and may improve the prognosis. Some breast cancer patients can safely take HRT and some formulations might reduce the subsequent risk of relapse.
Faiz
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Breast Unit, Guy's Hospital, London, UK.
Fentiman
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D001943:Breast Neoplasms / Q000139:chemically induced* / Q000235:genetics / Q000401:mortality; D015914:Estrogen Replacement Therapy / Q000009:adverse effects*; D004967:Estrogens / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008134:Long-Term Care; D011379:Prognosis; D012306:Risk
D004967:Estrogens