[Proliferative properties of cell differons in the vascular wall].
Using quantitative methods (radioautography using thymidine label, DNA cytophotometry and mitotic index definition) proliferative properties of the vascular wall main cell differons (endothelium, smooth myocytes and fibroblasts) were investigated in 60 rats during postnatal and reparative morphogenesis. Most pronounced DNA synthesis was noted to occur in aortal endothelium in newborn animals and in fibroblasts of adventitia in 1 and 6 months and old aged (2.5 years) rats. In various vessel types of adult animals significant differences of label incorporation in fibroblasts of adventitia were not revealed whereas endothelial daily proliferation pool varies significantly showing minimal value (0.5%) in inferior caval vein and maximal (6%)-in capillaries. During the regenerative morphogenesis of aorta, caused by adventita cryodestruction proliferative activity elevation was noted in all the cell types, most reactive of them being smooth myocyte differon of the media.
Gansburgskiĭ
A N
AN
Department of Histology, Embryology and Cytology, State Medical Academy of Yaroslavle.
Pavlov
A V
AV
D000818:Animals; D001011:Aorta / Q000166:cytology; D001345:Autoradiography; D002455:Cell Division / Q000502:physiology; D004247:DNA / Q000096:biosynthesis; D004730:Endothelium, Vascular / Q000166:cytology* / Q000196:embryology / Q000254:growth & development; D005347:Fibroblasts / Q000166:cytology; D008297:Male; D008940:Mitotic Index; D009024:Morphogenesis; D009131:Muscle, Smooth, Vascular / Q000166:cytology*; D051381:Rats; D014682:Vena Cava, Inferior / Q000166:cytology
D004247:DNA
Proliferativnye svoĭstva kletochnykh differonov sosudistoĭ stenki.