title: [Laugier-Hunziker syndrome. A clinical and anatomopathologic study. Presentation of 13 cases].
abstract: We report the clinico-pathologic characteristics of 13 cases of Laugier-Hunziker disease, consisting of the presence of oral melanotic macules associated or not to longitudinal nail pigmentation. The presence of regular acanthosis, basal pigmentation without increase in the number of melanocytes and the presence of melanophages in subepidermal connective tissue have been the most constant histopathological characteristics. The term "essential cutaneo-mucous hyperpigmentation" as synonym of Laugier-Hunziker disease is proposed.
authors.affiliation: Faculté de Médecine et Odontologie c/Entrerrios s/n, Saint Jacques de Compostelle, Espagne.
authors.forename: J M
authors.initials: JM
authors.lastname: Seoane Lestón
authors.forename: J
authors.initials: J
authors.lastname: Vázquez García
authors.forename: A M
authors.initials: AM
authors.lastname: Cazenave Jiménez
authors.forename: A
authors.initials: A
authors.lastname: de la Cruz Mera
authors.forename: A
authors.initials: A
authors.lastname: Aguado Santos
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003238:Connective Tissue / Q000473:pathology; D004817:Epidermis / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000473:pathology; D008548:Melanosis / Q000473:pathology*; D008875:Middle Aged; D009059:Mouth Diseases / Q000473:pathology*; D009260:Nail Diseases / Q000473:pathology*; D010859:Pigmentation Disorders / Q000473:pathology*; D013577:Syndrome
vernacular_title: Syndrome de Laugier-Hunziker. Etude clinique et anatomopathologique. Présentation de treize cas.