[The immunomodulating and antioxidant action of beta-carotene and essentiale in a lipid metabolic disorder].
Excessive supply of lipids to the organism of rats causes increase in lipid peroxidation, reduction of red cell energy status, the appearance in them of immunosuppressive properties, and inhibition of immunological reactivity. Administration of beta-carotene and essential corrects the biochemical status and immunological reactivity of the organism in alimentary lipid loading. beta-Carotene cancels the immunosuppressive properties of light red blood cells, whereas essential induces the appearance of immunostimulating properties in the heavy cells.
Uteshev
B S
BS
Department of Pharmacology, Russian State Medical University, Moscow, Russia.
Baĭburin
F Ia
FIa
Prokopenko
L G
LG
D000276:Adjuvants, Immunologic / Q000627:therapeutic use*; D000818:Animals; D000921:Antibody-Producing Cells / Q000187:drug effects / Q000276:immunology; D000975:Antioxidants / Q000627:therapeutic use*; D004041:Dietary Fats / Q000008:administration & dosage; D004734:Energy Metabolism / Q000187:drug effects; D004912:Erythrocytes / Q000187:drug effects / Q000378:metabolism; D015228:Hypertriglyceridemia / Q000097:blood / Q000188:drug therapy* / Q000209:etiology / Q000276:immunology; D007114:Immunization / Q000379:methods; D015227:Lipid Peroxidation / Q000187:drug effects; D010713:Phosphatidylcholines / Q000627:therapeutic use*; D051381:Rats; D017208:Rats, Wistar; D013154:Spleen / Q000187:drug effects / Q000276:immunology; D013997:Time Factors; D019207:beta Carotene / Q000627:therapeutic use*
D000276:Adjuvants, Immunologic; D000975:Antioxidants; D004041:Dietary Fats; D010713:Phosphatidylcholines; D019207:beta Carotene; C011246:essential 303 forte
Immunomoduliruiushchee i antioksidantnoe deĭstvie beta-karotina i éssentsiale pri narushenii lipidnogo obmena.