title: [Acquired toxoplasmosis with cerebral involvement and subsequent hearing loss].
abstract: In immunocompetent patients the postnatally acquired toxoplasmosis is usually a mild or asymptomatic disease. CNS manifestations are rare, e.g. in patients with HIV infection or in patients with other types of immunosuppression. We report on a 9-year old healthy boy, who was hospitalized after one week with subfebrile temperatures and headache with clinical signs of encephalitis and unilateral deafness. We diagnosed a toxoplasmosis and treated the patient with pyrimethamine and sulfadiazine. While most of the signs and symptoms disappeared rapidly the deafness persisted.
authors.affiliation: Universitätskinderklinik, Universität Leipzig.
authors.forename: D
authors.initials: D
authors.lastname: Rösch
authors.forename: W
authors.initials: W
authors.lastname: Handrick
authors.forename: R
authors.initials: R
authors.lastname: Lietz
authors.forename: R
authors.initials: R
authors.lastname: Blatz
authors.forename: E
authors.initials: E
authors.lastname: König
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D001309:Auditory Threshold; D002648:Child; D005500:Follow-Up Studies; D006316:Hearing Loss, High-Frequency / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D016781:Toxoplasmosis, Cerebral / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
vernacular_title: Erworbene Toxoplasmose mit zerebraler Beteiligung und nachfolgender Hörstörung.