Culture-negative endocarditis caused by Bartonella henselae.
A 4-year-old girl presented with clinical evidence of infective endocarditis involving her aortic valve, but blood cultures were sterile. Serologic studies and analysis of resected valve by immunohistochemistry and polymerase chain reaction established the diagnosis of Bartonella henselae endocarditis. Clinicians should be aware that B. henselae can cause apparent culture-negative endocarditis in children.
Baorto
E
E
Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri 63110, USA.
Payne
R M
RM
Slater
L N
LN
Lopez
F
F
Relman
D A
DA
Min
K W
KW
St Geme
J W
JW
D000907:Antibodies, Bacterial / Q000097:blood; D001021:Aortic Valve / Q000737:chemistry / Q000473:pathology; D018416:Bartonella henselae / Q000302:isolation & purification*; D002372:Cat-Scratch Disease / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D002675:Child, Preschool; D004697:Endocarditis, Bacterial / Q000175:diagnosis / Q000382:microbiology* / Q000601:surgery; D005260:Female; D006330:Heart Defects, Congenital / Q000150:complications / Q000601:surgery; D006801:Humans; D007124:Immunoenzyme Techniques; D007150:Immunohistochemistry; D016133:Polymerase Chain Reaction
D000907:Antibodies, Bacterial