Immunoglobulin G crystalline keratopathy associated with monoclonal gammopathy.
OBJECTIVE
Two cases of corneal crystal deposition are reported, both caused by a benign monoclonal gammopathy


METHODS
Similar corneal pathology is identified in these two patients, both of whom presented with visual acuities of 6/6 or better Consideration of possible causes involved biochemical and haematological testing and assessment.


RESULTS
Potential for malignant transformation of monoclonal gammopathy was recognized, hence the need for ongoing haematological follow-up.


CONCLUSIONS
Corneal crystals may be the initial presentation in a patient with monoclonal gammopathy, a rare, but significant, clinical finding.
Hutchinson
K
K
The Eye Unit, Greenslopes Private Hospital, Brisbane, Queensland, Australia.
Dal Pra
M
M
Apel
A
A
D001799:Blood Sedimentation; D002851:Chromatography, High Pressure Liquid; D003315:Cornea / Q000473:pathology*; D003316:Corneal Diseases / Q000150:complications / Q000175:diagnosis*; D003460:Crystallization; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007074:Immunoglobulin G / Q000032:analysis*; D007145:Immunoglobulin kappa-Chains / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D010265:Paraproteinemias / Q000150:complications / Q000175:diagnosis*; D014792:Visual Acuity
D007074:Immunoglobulin G; D007145:Immunoglobulin kappa-Chains