title: Alteration of esophageal pressure in sleep-disordered breathing.
abstract: We investigated the alteration of esophageal pressure (Pes) in 10 patients with upper-airway sleep-disordered breathing (UASDB) and the relationship among Pes, breathing patterns and EEG arousals. Increased negative Pes without apnea or hypopnea, appeared not only in upper airway resistance syndrome but also in obstructive sleep apnea syndrome. This phenomenon produced frequent EEG microarousals leading to sleep fragmentation and daytime sleepiness. Moreover, increased negative Pes occasionally continued for more than 20 min without an EEG arousal, which might be considered to be one of the factors to cause complications of UASDB.
authors.affiliation: Department of Neuropsychiatry, Osaka University Medical School, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Mikami
authors.forename: T
authors.initials: T
authors.lastname: Watanabe
authors.forename: M
authors.initials: M
authors.lastname: Motonishi
authors.forename: H
authors.initials: H
authors.lastname: Honda
authors.forename: K
authors.initials: K
authors.lastname: Kyotani
authors.forename: S
authors.initials: S
authors.lastname: Uruha
authors.forename: K
authors.initials: K
authors.lastname: Terashima
authors.forename: Y
authors.initials: Y
authors.lastname: Teshima
authors.forename: Y
authors.initials: Y
authors.lastname: Sugita
mesh_terms: D000328:Adult; D000368:Aged; D000403:Airway Resistance / Q000502:physiology; D001143:Arousal / Q000502:physiology*; D002540:Cerebral Cortex / Q000503:physiopathology; D002940:Circadian Rhythm / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D010100:Oxygen / Q000097:blood; D017286:Polysomnography; D012016:Reference Values; D012891:Sleep Apnea Syndromes / Q000175:diagnosis / Q000503:physiopathology*; D014939:Work of Breathing / Q000502:physiology
chemical_list: D010100:Oxygen