title: [Recent advance in alveolar formation].
abstract: Recent technological advance in both molecular biology and morphology contributes to develop a research of alveolar formation in pre- and postnatal period. Retinoid, which has been known more than 2,000 compounds, has a key role for newly alveolar synthesis through various metabolic pathways related Hox gene, vitamin A laden fibroblast and collagen-elastin network. It has been shown that retinoid is a possible therapeutic regimen not only diffuse lung injury, such as bronchopulmonary dysplasia, but also a hopeful new-drug for newly alveolar synthesis in severe emphysema.
authors.affiliation: Pulmonary Division, Tokyo Metropolitan Geriatric Hospital, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Kida
mesh_terms: D000818:Animals; D001997:Bronchopulmonary Dysplasia / Q000188:drug therapy; D002454:Cell Differentiation; D002455:Cell Division; D005801:Genes, Homeobox; D006801:Humans; D007231:Infant, Newborn; D011650:Pulmonary Alveoli / Q000166:cytology*; D011656:Pulmonary Emphysema / Q000188:drug therapy; D012176:Retinoids / Q000627:therapeutic use; D014801:Vitamin A / Q000502:physiology
chemical_list: D012176:Retinoids; D014801:Vitamin A