title: Hereditary hypotrichosis simplex.
abstract: Hypotrichosis is a relatively common feature of a number of complex hereditary syndromes. However, the isolated variant, called hereditary hypotrichosis simplex (HHS), is especially uncommon. We present a Spanish family with 8 of 19 persons covering 4 generations affected by HHS. No associated ectodermal or other defects were noted. The pedigree was compatible with an autosomal dominant inheritance with variable penetrance.
authors.affiliation: Department of Dermatology, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Just
authors.forename: M
authors.initials: M
authors.lastname: Ribera
authors.forename: M J
authors.initials: MJ
authors.lastname: Fuente
authors.forename: I
authors.initials: I
authors.lastname: Bielsa
authors.forename: C
authors.initials: C
authors.lastname: Ferrándiz
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D006801:Humans; D007039:Hypotrichosis / Q000175:diagnosis* / Q000235:genetics*; D008297:Male; D010375:Pedigree