title: [Iodine-125 implantation in localized cancer of the prostate; too early for rejoicing].
abstract: The role of I-125 implantation in treatment with curative intent of carcinoma of the prostate is not yet perfectly clear. No long-term results in large groups of patients have so far been published. An inherent restriction of the technique is that it is difficult to attain a high dose of radiation in the periphery of the prostate. Consequently, the technique appears to be less or not appropriate for peripherally located tumours or tumours with extracapsular spread. Implantation of I-125 should for the moment be regarded as an experimental therapy. Its application should be limited to strictly selected patients and should be carried out as a part of trials.
authors.affiliation: Nederlands Kanker Instituut/Antoni van Leeuwenhoek Ziekenhuis, Amsterdam.
authors.forename: L M
authors.initials: LM
authors.lastname: Moonen
authors.forename: S
authors.initials: S
authors.lastname: Horenblas
mesh_terms: D001918:Brachytherapy / Q000009:adverse effects / Q000379:methods*; D000075202:Contraindications; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D008297:Male; D009367:Neoplasm Staging; D011471:Prostatic Neoplasms / Q000473:pathology / Q000532:radiotherapy*
chemical_list: D007457:Iodine Radioisotopes
vernacular_title: Jodium-125-implantatie bij gelokaliseerd prostaatcarcinoom: niet te vroeg juichen.