title: KL-6 as a serologic indicator of Pneumocystis carinii pneumonia in immunocompromised hosts.
abstract: KL-6, a serum marker for interstitial pneumonitis, was evaluated in patients with Pneumocystis carinii pneumonia (PCP). Patient 1 was a 56-year-old woman with rheumatoid arthritis treated with immunosuppressive drugs and corticosteroids. Patient 2 was a 59-year-old man with a glioblastoma who received anti-cancer drugs and corticosteroids. In both patients, serum KL-6 showed an abnormally high level due to the complication of PCP, and it decreased following successful treatment. These results indicate that PCP is one of the diseases in which serum KL-6 increases.
authors.affiliation: Department of Internal Medicine, National Kinki-Chuo Hospital for Chest Diseases, Osaka.
authors.forename: H
authors.initials: H
authors.lastname: Hamada
authors.forename: N
authors.initials: N
authors.lastname: Kohno
authors.forename: A
authors.initials: A
authors.lastname: Yokoyama
authors.forename: Y
authors.initials: Y
authors.lastname: Hirasawa
authors.forename: K
authors.initials: K
authors.lastname: Hiwada
authors.forename: M
authors.initials: M
authors.lastname: Sakatani
authors.forename: E
authors.initials: E
authors.lastname: Ueda
mesh_terms: D000941:Antigens; D000951:Antigens, Neoplasm; D001172:Arthritis, Rheumatoid / Q000150:complications / Q000188:drug therapy; D015415:Biomarkers / Q000097:blood*; D001706:Biopsy; D001932:Brain Neoplasms / Q000150:complications / Q000188:drug therapy; D005260:Female; D005500:Follow-Up Studies; D005909:Glioblastoma / Q000150:complications / Q000188:drug therapy; D006023:Glycoproteins; D006801:Humans; D016867:Immunocompromised Host; D007150:Immunohistochemistry; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D018396:Mucin-1; D009077:Mucins / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood*; D011020:Pneumonia, Pneumocystis / Q000097:blood* / Q000150:complications / Q000473:pathology; D011347:Procollagen / Q000097:blood*
chemical_list: D000941:Antigens; D000951:Antigens, Neoplasm; D015415:Biomarkers; D006023:Glycoproteins; D007166:Immunosuppressive Agents; C060192:MUC1 protein, human; D018396:Mucin-1; D009077:Mucins; D010446:Peptide Fragments; D011347:Procollagen; C041876:procollagen Type III-N-terminal peptide