title: Transendoscopic chemical ablation of progressive ethmoidal hematomas in standing horses.
abstract: OBJECTIVE
  To examine the response of horses with progressive ethmoidal hematoma (PEH) to intralesional injection of 4% formaldehyde solution.
  
  
  METHODS
  Nasal passages of horses affected with PEH were examined endoscopically at different intervals to determine the effects of intralesional injection of formaldehyde solution.
  
  
  METHODS
  21 horses with PEH.
  
  
  METHODS
  PEHs were injected transendoscopically with 4% formaldehyde solution. Horses were examined endoscopically and retreated at different intervals until the PEH was eliminated or was so small that reinjection was not possible.
  
  
  RESULTS
  Lesions diminished significantly in size or were eliminated after 1 to 18 injections (median, 5; mean, 7.0 +/- 5.62). Seventeen lesions (60.7%) resolved completely after 1 to 18 injections (median, 5; mean, 7.2 +/- 5.71). Five lesions decreased markedly in size but did not resolve after receiving 1 to 18 injections (median, 5; mean, 7.6 +/- 6.66). Injection of these lesions was discontinued 4.0 to 25.1 months (median, 9.5; mean, 11.02 +/- 8.446) after the first injection. The PEH of one horse was removed surgically after one injection. Three horses, one with bilateral PEH, were lost to follow-up. One horse developed signs of laminitis. No other complications were observed.
  
  
  CONCLUSIONS
  Horses with a PEH can be treated effectively by transendoscopic, intralesional injection of 4% formaldehyde solution.
  
  
  CONCLUSIONS
  Ablation of PEH using formaldehyde solution avoids general anesthesia and problems associated with ablation by conventional surgery or laser.
authors.affiliation: Department of Large Animal Medicine and Surgery, Texas Veterinary Medical Center, College of Veterinary Medicine, College Station, USA.
authors.forename: J
authors.initials: J
authors.lastname: Schumacher
authors.forename: T
authors.initials: T
authors.lastname: Yarbrough
authors.forename: J
authors.initials: J
authors.lastname: Pascoe
authors.forename: P
authors.initials: P
authors.lastname: Woods
authors.forename: D
authors.initials: D
authors.lastname: Meagher
authors.forename: C
authors.initials: C
authors.lastname: Honnas
mesh_terms: D000818:Animals; D004724:Endoscopy / Q000662:veterinary; D005005:Ethmoid Sinus; D005260:Female; D005557:Formaldehyde / Q000008:administration & dosage / Q000627:therapeutic use*; D006406:Hematoma / Q000628:therapy / Q000662:veterinary*; D006734:Horse Diseases / Q000628:therapy*; D006736:Horses; D015552:Injections, Intralesional / Q000662:veterinary; D008297:Male; D010254:Paranasal Sinus Diseases / Q000628:therapy / Q000662:veterinary*; D012996:Solutions; D016896:Treatment Outcome
chemical_list: D012996:Solutions; D005557:Formaldehyde