The expression pattern of endothelin 3 in the avian embryo.
We investigated the expression pattern of the endothelin 3 gene, of which the mutation, as well as mutation of its receptor (endothelin-B receptor), affects the development of two neural crest derivatives: enteric nervous system and melanocytes. After previous work showing that these neural crest derived cells express endothelin-B receptor or its subtype endothelin-B2 receptor in the avian embryo, we have demonstrated that endothelin 3 is expressed by the environment of enteric nervous system and melanocyte precursors.
Nataf
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Institut d'Embryologie Cellulaire et Moléculaire du Centre National de la Recherche Scientifique et du Collège de France, 49 bis Avenue de la Belle Gabrielle, 94736, Nogent-sur-Marne Cedex, France.
Amemiya
A
A
Yanagisawa
M
M
Le Douarin
N M
NM
D000818:Animals; D002642:Chick Embryo; D004625:Embryo, Nonmammalian / Q000378:metabolism*; D019334:Endothelin-3 / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism
D019334:Endothelin-3; D012333:RNA, Messenger