title: A preliminary assessment of intra-oral lubricating systems for dry mouth patients.
abstract: OBJECTIVE
  To provide extended intra-oral delivery of a saliva substitute.
  
  
  METHODS
  Three different types of prostheses containing saliva substitute were designed and assessed: a two-part device resembling a mandibular complete denture sealed by cobalt-samerium magnets, a one-part clear resin device for the edentate patients and a flexible mouth guard type of appliance containing a lubricant releasing bubble for the dentate patients.
  
  
  METHODS
  A teaching hospital Oral Medicine and Rheumatology Clinic.
  
  
  METHODS
  8 edentate and 3 dentate Sjogren Syndrome sufferers.
  
  
  METHODS
  Subjective dryness after a week of wearing the lubricating appliance.
  
  
  RESULTS
  The majority of the subjects wore the appliances for 6-12 hours during each 24 hours. The initial dryness severity diminished after wearing the lubricating prosthesis. The patients preferred to wear the appliance at night.
  
  
  CONCLUSIONS
  All criteria were fulfilled on designing a saliva substitute lubricating appliance and some of the subjects have worn this prosthesis successfully for up to 3 years. Particular benefit was obtained by night-time wear.
authors.affiliation: Department of Prosthetic Dentistry, UMDS, London.
authors.forename: P M
authors.initials: PM
authors.lastname: Frost
authors.forename: R M
authors.initials: RM
authors.lastname: Gardner
authors.forename: A R
authors.initials: AR
authors.lastname: Price
authors.forename: G F
authors.initials: GF
authors.lastname: Sinclair
mesh_terms: D000368:Aged; D017267:Dental Prosthesis Design; D003779:Denture Design; D003826:Denture, Complete, Lower; D016503:Drug Delivery Systems / Q000295:instrumentation*; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D008297:Male; D012464:Saliva, Artificial / Q000008:administration & dosage*; D012859:Sjogren's Syndrome / Q000628:therapy*; D011795:Surveys and Questionnaires
chemical_list: D012464:Saliva, Artificial