title: [Variable changes in immune reactivity and stress-sensitivity as a factor of selection of adaptation strategy under unfavorable conditions].
abstract: Experimental data are provided which substantiate the concept on reciprocal changes in immune reactivity and stress sensitivity as a basis for selection of adaptation strategy under unfavorable conditions. The data obtained suggest that transition from the resistant (stress) strategy of adaptation to hypobiosis is a prerequisite for maintenance of the immune reactivity under extreme conditions. Stimulation of the immune system per se may provide for transition from stress to the tolerant (hypobiotic) strategy of adaptation.
authors.affiliation: State Medical Academy of Chelyabinsk, Russia.
authors.forename: I A
authors.initials: IA
authors.lastname: Volchegorskiĭ
authors.forename: V E
authors.initials: VE
authors.lastname: Tseĭlikman
authors.forename: O L
authors.initials: OL
authors.lastname: Kolesnikov
mesh_terms: D000209:Acute-Phase Proteins / Q000276:immunology; D000222:Adaptation, Physiological / Q000187:drug effects / Q000276:immunology*; D000276:Adjuvants, Immunologic / Q000494:pharmacology; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology; D000818:Animals; D000921:Antibody-Producing Cells / Q000187:drug effects / Q000276:immunology*; D001921:Brain / Q000201:enzymology / Q000276:immunology; D005230:Fatty Acids, Nonesterified / Q000097:blood; D006003:Glycogen / Q000378:metabolism; D006968:Hypersensitivity, Delayed / Q000276:immunology; D000860:Hypoxia / Q000276:immunology; D007103:Immobilization; D007375:Interleukin-1 / Q000097:blood / Q000276:immunology; D017737:Macrophages, Peritoneal / Q000187:drug effects / Q000276:immunology; D008995:Monoamine Oxidase / Q000378:metabolism; D009043:Motor Activity / Q000187:drug effects / Q000276:immunology; D009504:Neutrophils / Q000187:drug effects / Q000276:immunology; D011433:Propranolol / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D013312:Stress, Physiological / Q000097:blood / Q000276:immunology* / Q000378:metabolism / Q000503:physiopathology
chemical_list: D000209:Acute-Phase Proteins; D000276:Adjuvants, Immunologic; D000319:Adrenergic beta-Antagonists; D005230:Fatty Acids, Nonesterified; D007375:Interleukin-1; D006003:Glycogen; D011433:Propranolol; D008995:Monoamine Oxidase
vernacular_title: Raznonapravlennost' izmeneniĭ immunnoĭ reaktivnosti i stress-chuvstvitel'nosti kak faktor vybora adaptatsionnoĭ strategii v neblagopriiatnykh usloviiakh.