Genetic approaches to adoptive cellular immunotherapy.
The ability to modify cells to express foreign genes has provided new venues in the treatment of cancer. These techniques have enabled investigators to generate more potent immune effector cells capable of mediating regression of established tumors. Some of these techniques are currently being evaluated in clinical trials.
Salas
A P
AP
Division of Surgical Oncology, University of Michigan, Ann Arbor, Michigan 48109-0932, USA.
Chang
A E
AE
D000818:Animals; D018014:Gene Transfer Techniques; D006801:Humans; D016219:Immunotherapy, Adoptive; D009369:Neoplasms / Q000628:therapy*