title: Bone cement reconstruction of the ossicular chain: a preliminary report.
abstract: OBJECTIVE
  To determine the feasibility and efficacy of using a bone cement, Oto-Cem, to reconstruct the ossicular chain.
  
  
  METHODS
  Prospective clinical trial on nine consecutively chosen adult patients with ossicular chain defects.
  
  
  METHODS
  Nine patients with ossicular chain defects involving the long process of the incus were treated at the Carolina Ear and Hearing Clinic. The ossicular chain was reconstructed using bone cement by itself or in conjunction with a stapes prosthesis.
  
  
  METHODS
  Preoperative audiograms were compared with audiograms 3, 6, and 12 months after reconstruction.
  
  
  RESULTS
  There was a mean pure-tone average (PTA) improvement of 15 dB in patients undergoing incus to stapes suprastructure reconstruction with the bone cement. The incus to mobile footplate reconstruction (using a stapes prosthesis attached to the newly reconstructed incus) resulted in a 34-dB PTA postoperative improvement. Two of the three patients with incus to oval window repairs experienced a 10-dB improvement in PTA. One of the three patients experienced a loss in speech discrimination and a 2-dB loss in PTA.
  
  
  CONCLUSIONS
  Despite the limited number of patients, this preliminary study demonstrates the effectiveness of Oto-Cem in reconstructing a foreshortened incus. There was a substantial hearing improvement in all but one patient in the incus to stapes or the incus to footplate categories.
authors.affiliation: Montifiore Medical Center, Bronx, New York, USA.
authors.forename: J G
authors.initials: JG
authors.lastname: Feghali
authors.forename: D M
authors.initials: DM
authors.lastname: Barrs
authors.forename: C W
authors.initials: CW
authors.lastname: Beatty
authors.forename: D A
authors.initials: DA
authors.lastname: Chen
authors.forename: J D
authors.initials: JD
authors.lastname: Green
authors.forename: W W
authors.initials: WW
authors.lastname: Krueger
authors.forename: C
authors.initials: C
authors.lastname: Shelton
authors.forename: W H
authors.initials: WH
authors.lastname: Slattery
authors.forename: B S
authors.initials: BS
authors.lastname: Thedinger
authors.forename: D F
authors.initials: DF
authors.lastname: Wilson
authors.forename: J T
authors.initials: JT
authors.lastname: McElveen
mesh_terms: D001309:Auditory Threshold; D001843:Bone Cements / Q000627:therapeutic use*; D004429:Ear Ossicles / Q000601:surgery*; D006314:Hearing Loss, Conductive / Q000175:diagnosis; D006801:Humans; D011182:Postoperative Care; D011300:Preoperative Care; D011446:Prospective Studies; D019919:Prosthesis Implantation; D013997:Time Factors
chemical_list: D001843:Bone Cements