title: CT of neural plexus invasion in common bile duct carcinoma.
abstract: OBJECTIVE
  Our purpose was to analyze the CT findings of neural plexus invasion in common bile duct carcinoma.
  
  
  METHODS
  We studied 16 patients with common bile duct carcinoma who underwent surgery. Of these, neural invasion was seen in 10 patients. CT findings were retrospectively reviewed and correlated with the surgical and pathological findings.
  
  
  RESULTS
  Irregular masses adjacent to the medial aspect of the uncinate process were observed in 4 of 14 patients with distal common bile duct carcinoma. These lesions extended medially and showed contiguity with the superior mesenteric artery and/or celiac axis, corresponding to neural plexus invasion with desmoplastic change. Increased attenuation of the fat between the common bile duct and the proper hepatic artery was seen in two of two patients with proximal common bile duct carcinoma, associated with neural plexus invasion in the hepatoduodenal ligament.
  
  
  CONCLUSIONS
  The location and spread of neural plexus invasion in common bile duct carcinoma are characteristic and can be diagnosed by CT.
authors.affiliation: Department of Radiology, Nagasaki University School of Medicine, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Fukuda
authors.forename: S
authors.initials: S
authors.lastname: Iwanaga
authors.forename: I
authors.initials: I
authors.lastname: Sakamoto
authors.forename: N
authors.initials: N
authors.lastname: Aso
authors.forename: K
authors.initials: K
authors.lastname: Nagaoki
authors.forename: K
authors.initials: K
authors.lastname: Hayashi
authors.forename: H
authors.initials: H
authors.lastname: Yamaguchi
authors.forename: S
authors.initials: S
authors.lastname: Okudaira
authors.forename: T
authors.initials: T
authors.lastname: Tomioka
authors.forename: T
authors.initials: T
authors.lastname: Okimoto
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D000273:Adipose Tissue / Q000000981:diagnostic imaging / Q000473:pathology; D000328:Adult; D000368:Aged; D002447:Celiac Plexus / Q000000981:diagnostic imaging* / Q000473:pathology; D003135:Common Bile Duct / Q000000981:diagnostic imaging / Q000473:pathology; D003138:Common Bile Duct Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D004386:Duodenum / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D005355:Fibrosis; D006499:Hepatic Artery / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008022:Ligaments / Q000000981:diagnostic imaging / Q000473:pathology; D008099:Liver / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D017538:Mesenteric Artery, Superior / Q000000981:diagnostic imaging / Q000473:pathology; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009412:Nerve Fibers / Q000000981:diagnostic imaging* / Q000473:pathology; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed