Modelling the incidence of measles in Canada: an assessment of the options for vaccination policy.
A range of vaccination policy options for improving the control of measles in Canada is investigated using a mathematical model to simulate transmission of the disease. Results suggest that a catch up campaign giving a second dose of vaccine to children aged up to 18 years would have an immediate impact on transmission, which could be maintained by the introduction of a routine second dose at either 18 months or 5 years of age. Introducing a routine second dose of vaccine without a catch up campaign would allow continued endemic transmission of measles among older children for at least 10-15 years.
Gay
N J
NJ
Immunisation Division, PHLS Communicable Disease Surveillance Centre, London, UK.
Pelletier
L
L
Duclos
P
P
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000367:Age Factors; D000368:Aged; D002170:Canada / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006291:Health Policy; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008457:Measles / Q000453:epidemiology* / Q000517:prevention & control / Q000635:transmission; D008458:Measles Vaccine / Q000008:administration & dosage*; D008875:Middle Aged; D018448:Models, Immunological; D008962:Models, Theoretical; D011159:Population Surveillance; D014611:Vaccination
D008458:Measles Vaccine