title: Staphylococcal endophthalmitis following cataract extraction in a patient with Darier's disease.
abstract: OBJECTIVE
  To report staphylococcal endophthalmitis following cataract extraction in a patient with Darier' s disease.
  
  
  METHODS
  A 67-year-old man presented with decreased visual acuity OD and hypopyon 3 days status post-cataract extraction with intraocular lens placement. The patient was hospitalized and placed on topical and intravenous antibiotics. A diagnostic vitreous tap, pars plana vitrectomy, and intravitreal antibiotic installation were performed.
  
  
  RESULTS
  Vitreal tap cultures indicated Staphylococcus epidermidis. His clinical status improved after vitrectomy and antibiotic therapy. The same bacteria was cultured from the patient's eyelids.
  
  
  CONCLUSIONS
  The source of the S. epidermidis was the skin lesions on the patient's face and eyelids. Darier's disease is an exfoliative hyperkeratotic skin disease that affects all areas on the body except the buttocks. Although clean, sterile surgical techniques were followed, the risk of endophthalmitis following intraocular surgery in a patient with Darier's disease may be increased due to his or her dermatologic condition.
authors.affiliation: Department of Ophthalmology, West Virginia University School of Medicine, Morgantown 26506, USA.
authors.forename: M S
authors.initials: MS
authors.lastname: Macsai
authors.forename: S
authors.initials: S
authors.lastname: Agarwal
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents; D002386:Cataract / Q000150:complications; D002387:Cataract Extraction / Q000009:adverse effects*; D007644:Darier Disease / Q000150:complications*; D004333:Drug Administration Routes; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D009877:Endophthalmitis / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D005500:Follow-Up Studies; D006801:Humans; D019654:Lens Implantation, Intraocular; D008297:Male; D011183:Postoperative Complications; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D013212:Staphylococcus epidermidis / Q000302:isolation & purification*; D014821:Vitrectomy; D014822:Vitreous Body / Q000382:microbiology / Q000601:surgery
chemical_list: D000900:Anti-Bacterial Agents