title: Marked left ventricular hypertrophy in children on tacrolimus (FK506) after orthotopic liver transplantation.
abstract: Although the cardiac effects of tacrolimus (FK506) have not been well documented, clinical cases of children on FK506 who developed hypertrophic obstructive cardiomyopathy have been reported. We report 2 cases of marked concentric hypertrophy of the left ventricular myocardium found at autospy in children on FK506.
authors.affiliation: Department of Pediatrics, UCLA Medical Center, Los Angeles, California 90024, USA.
authors.forename: R K
authors.initials: RK
authors.lastname: Chang
authors.forename: M
authors.initials: M
authors.lastname: Alzona
authors.forename: J
authors.initials: J
authors.lastname: Alejos
authors.forename: K
authors.initials: K
authors.lastname: Jue
authors.forename: S V
authors.initials: SV
authors.lastname: McDiarmid
mesh_terms: D002648:Child; D005260:Female; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000139:chemically induced* / Q000473:pathology*; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D007231:Infant, Newborn; D016031:Liver Transplantation; D008297:Male; D016559:Tacrolimus / Q000009:adverse effects*
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus