title: [Hepatic arterial infusion chemotherapy (HAI) for advanced hepatocellular carcinoma inefficacious with transcatheter arterial embolization (TAE)].
abstract: For 6 patients with advanced hepatocellular carcinoma (HCC) in whom TAE was inefficacious, we tried hepatic arterial infusion chemotherapy. 5-FU 500 mg/day + CDDP 10 mg/day was administered during 5 days. The AFP level was decreased for 4 patients, and 2 patients showed a partial response in CT image. These 2 patients have been alive over 22 and 18 months, respectively. These results suggest that 5-FU + CDDP HAI might be a useful treatment of HCC inefficacious with TAE.
authors.affiliation: Second Dept. of Surgery, Chiba University School of Medicine.
authors.forename: W
authors.initials: W
authors.lastname: Takayama
authors.forename: T
authors.initials: T
authors.lastname: Asano
authors.forename: S
authors.initials: S
authors.lastname: Kobayashi
authors.forename: S
authors.initials: S
authors.lastname: Nakagouri
authors.forename: T
authors.initials: T
authors.lastname: Kenmochi
authors.forename: S
authors.initials: S
authors.lastname: Okazumi
authors.forename: A
authors.initials: A
authors.lastname: Takeda
authors.forename: T
authors.initials: T
authors.lastname: Fukunaga
authors.forename: K
authors.initials: K
authors.lastname: Iwasaki
authors.forename: K
authors.initials: K
authors.lastname: Shutou
authors.forename: H
authors.initials: H
authors.lastname: Matsuzaki
authors.forename: H
authors.initials: H
authors.lastname: Aoyama
authors.forename: K
authors.initials: K
authors.lastname: Shinotou
authors.forename: T
authors.initials: T
authors.lastname: Kouno
authors.forename: K
authors.initials: K
authors.lastname: Isono
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D016461:Chemoembolization, Therapeutic; D002945:Cisplatin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D005472:Fluorouracil / Q000008:administration & dosage; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000628:therapy*; D008297:Male; D008875:Middle Aged
chemical_list: D002945:Cisplatin; D005472:Fluorouracil