title: [The histopathologic picture of experimental poisoning with ethylmethacrylates].
abstract: Toxic effect of hydroxyethylmethacrylate, acetoxyethylmethacrylate and diethylenglycomethacrylate were studied in rats surviving as long as 1 to 20 days after intramuscular administration. Conspicuous lesion were found only in calf muscles at the site of application. Muscle fibre necroses with inflammatory reaction occurred repeatedly in animals surviving 1-2 days. Newly formed connective tissue replacing impaired muscle fibres was found in rats surviving 5 days. Intoxication related other lesion in rat organs were not identified.
authors.affiliation: Ustav soudního lékarství VFN a 1. LF UK, Praha.
authors.forename: F
authors.initials: F
authors.lastname: Nádvorník
authors.forename: P
authors.initials: P
authors.lastname: Schneiderka
authors.forename: M
authors.initials: M
authors.lastname: Roosová
authors.forename: J
authors.initials: J
authors.lastname: Vacík
authors.forename: J
authors.initials: J
authors.lastname: Labský
mesh_terms: D000818:Animals; D005260:Female; D008689:Methacrylates / Q000633:toxicity*; D018482:Muscle, Skeletal / Q000187:drug effects / Q000473:pathology; D051381:Rats; D017208:Rats, Wistar
chemical_list: D008689:Methacrylates
vernacular_title: Histopatologický obraz experimentální intoxikace ethylmethakryláty.