Drug-induced systemic lupus erythematosus after 8 years of treatment with carbamazepine.
This is the report of a late-onset carbamazepine-induced systemic lupus erythematosus in a 34-year-old patient who had been treated with daily carbamazepine for 8 years because of complex partial seizures. When carbamazepine was discontinued, symptoms rapidly improved and antinuclear antibodies disappeared. So far, few cases have been reported of carbamazepine-induced lupus erythematosus within months after the start of treatment. This is the first case report about carbamazepine-induced systemic lupus erythematosus with serological confirmation after years of treatment without side effects.
Toepfer
M
M
Friedrich-Baur-Institut, Medizinische Kunik, Klinikum Innenstadt, Ludwig-Maximillians-Universität, Munich, Germany.
Sitter
T
T
Lochmüller
H
H
Pongratz
D
D
Müller-Felber
W
W
D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects* / Q000097:blood; D002220:Carbamazepine / Q000009:adverse effects* / Q000097:blood; D004828:Epilepsies, Partial / Q000188:drug therapy; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000139:chemically induced*; D008297:Male
D000927:Anticonvulsants; D002220:Carbamazepine