title: Low molecular weight heparin-induced skin necrosis occurring distant from injection sites and without thrombocytopenia.
abstract: In this paper we report a case of 76-year-old white male patient with skin necrosis induced by subcutaneous prophylactic administration of low-molecular-weight heparin (LMWH). Skin necrosis occurred distant from heparin injection sites and without concomitant thrombocytopenia. This is the first reported case presenting these clinical findings.
authors.affiliation: Department of Gastroenterology and Hepatology, Medizinische Hochschule Hannover, Germany.
authors.forename: U J
authors.initials: UJ
authors.lastname: Tietge
authors.forename: H H
authors.initials: HH
authors.lastname: Schmidt
authors.forename: E
authors.initials: E
authors.lastname: Jäckel
authors.forename: C
authors.initials: C
authors.lastname: Trautwein
authors.forename: M P
authors.initials: MP
authors.lastname: Manns
mesh_terms: D000368:Aged; D005343:Fibrinolytic Agents / Q000009:adverse effects*; D006495:Heparin, Low-Molecular-Weight / Q000009:adverse effects*; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D009336:Necrosis; D012867:Skin / Q000187:drug effects* / Q000473:pathology*; D013921:Thrombocytopenia
chemical_list: D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight