title: [Endocrine apparatus of the epithelium of the appendicular mucosa (the appendix-- an endocrine gland, functioning in the embryonal period?].
abstract: Based on the concept on gastroenteropancreatic system, endocrinocytes of which are diffusely scattered throughout the digestive tract epithelium and are found in pancreatic islets, an analysis of endocrine apparatus of epithelium in human appendicular mucosa was performed at different stages of ontogenesis. The response of appendicular endocrinocytes to clinical pathology of both this organ and the entire organism was studied. On the base of the analysis of the appendix function from morphological view, the authors proposed a hypothesis postulating it to be an organ equal to an actively functioning endocrine gland and its unique role on early stages of embryogenesis.
authors.affiliation: Department of Medical Biology and Gross Genetics, I.I. Mechnikov State Medical Academy, St. Petersburg.
authors.forename: S V
authors.initials: SV
authors.lastname: Kostiukevich
authors.forename: A A
authors.initials: AA
authors.lastname: Puzyrev
authors.forename: V F
authors.initials: VF
authors.lastname: Ivanova
mesh_terms: D001065:Appendix / Q000196:embryology* / Q000473:pathology; D002454:Cell Differentiation / Q000502:physiology; D005314:Embryonic and Fetal Development / Q000502:physiology; D004703:Endocrine System / Q000196:embryology* / Q000473:pathology; D004847:Epithelial Cells / Q000473:pathology*; D006801:Humans; D009092:Mucous Membrane / Q000196:embryology / Q000473:pathology
vernacular_title: Endokrinnyĭ apparat épiteliia slizistoĭ obolochki cherveobraznogo otrostka cheloveka (cherveobraznyĭ otrostok--éndokrinnaia zheleza, funktsioniruiushchaia v émbrional'nyĭ period?)