title: Protective effects of cruciferous seed meals and hulls against colon cancer in mice.
abstract: Protective effects of diets containing cruciferous seed meals or hulls against chemically-induced colon tumors were examined in male CF1 mice. When commercial crambe meal, autolyzed crambe meal, crambe hulls, high glucosinolate rapeseed meal, or canola meal were fed as 12% of the diets of mice injected with 1,2-dimethylhydrazine, 25-80% of the animals developed colon tumors. Animals fed a soybean meal control diet had a 100% tumor rate. Data suggest that cruciferous seed meals may contain a number of compounds that can exert protective effects against tumor formation and growth.
authors.affiliation: Department of Biology, Kansas State University, Manhattan 66506, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Barrett
authors.forename: C F
authors.initials: CF
authors.lastname: Klopfenstein
authors.forename: H W
authors.initials: HW
authors.lastname: Leipold
mesh_terms: D000818:Animals; D019607:Brassicaceae; D003110:Colonic Neoplasms / Q000517:prevention & control*; D004032:Diet; D004043:Dietary Fiber; D005961:Glucosinolates; D008297:Male; D051379:Mice; D019800:Phenol; D010833:Phytic Acid; D013634:Tannins
chemical_list: D004043:Dietary Fiber; D005961:Glucosinolates; D013634:Tannins; D019800:Phenol; D010833:Phytic Acid