cot1: a regulator of Arabidopsis trichome initiation.
In Arabidopsis, the timing and spatial arrangement of trichome initiation is tightly regulated and requires the activity of the GLABROUS1 (GL1) gene. The COTYLEDON TRICHOME 1 (COT1) gene affects trichome initiation during late stages of leaf development and is described in this article. In the wild-type background, cot1 has no observable effect on trichome initiation. GL1 overexpression in wild-type plants leads to a modest number of ectopic trichomes and to a decrease in trichome number on the adaxial leaf surface. The cot1 mutation enhances GL1-overexpression-dependent ectopic trichome formation and also induces increased leaf trichome initiation. The expressivity of the cot1 phenotype is sensitive to cot1 and 35S::GL1 gene dosage, and the most severe phenotypes are observed when cot1 and 35S::GL1 are homozygous. The COT1 locus is located on chromosome 2 15.3 cM north of er. Analysis of the interaction between cot1, try, and 35S::GL1 suggests that COT1 is part of a complex signal transduction pathway that regulates GL1-dependent adoption of the trichome cell fate.
Szymanski
D B
DB
Department of Genetics and Cell Biology, and Plant Molecular and Genetics Institute, University of Minnesota, St. Paul, Minnesota 55108, USA.
Klis
D A
DA
Larkin
J C
JC
Marks
M D
MD
D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development; D029681:Arabidopsis Proteins; D002874:Chromosome Mapping; D018548:Cotyledon / Q000235:genetics* / Q000254:growth & development / Q000648:ultrastructure; D004268:DNA-Binding Proteins / Q000235:genetics; D018507:Gene Expression Regulation, Developmental; D018506:Gene Expression Regulation, Plant / Q000235:genetics*; D017343:Genes, Plant / Q000502:physiology*; D005819:Genetic Markers; D006720:Homozygote; D010641:Phenotype; D010940:Plant Proteins / Q000235:genetics / Q000502:physiology; D030821:Plants, Genetically Modified; D014157:Transcription Factors / Q000235:genetics; D019076:Transgenes
D029681:Arabidopsis Proteins; D004268:DNA-Binding Proteins; D005819:Genetic Markers; D010940:Plant Proteins; D014157:Transcription Factors; C071556:GL1 protein, Arabidopsis