Calcium phosphate coatings for medical implants.
In surgical disciplines where bone has to be repaired, augmented or improved, bone substitutes are essential. Although bone banks, such as Eurotransplant, are founded to supply such substitutes, natural bone is not always adequate. For example, frequently these so-called bone grafts resorb after implantation (1). Further, they cannot be used for joint and tooth replacement, and recently worries have been raised about the transfer of infectious diseases. Therefore, interest has dramatically increased in the use of synthetic materials for replacement of lost or damaged bone tissue. The generic name of these tissue alternatives is biomaterials. A special class of these biomaterials is composed of metallic devices with coatings to improve bone bonding. These specialized coatings used to improve the metallic implant are the topic of this paper.
de Groot
K
K
Biomaterials Research Group, University of Leiden, The Netherlands.
Wolke
J G
JG
Jansen
J A
JA
D000268:Adhesiveness; D001672:Biocompatible Materials; D001673:Biodegradation, Environmental; D001842:Bone and Bones; D002130:Calcium Phosphates / Q000737:chemistry; D002516:Ceramics / Q000737:chemistry; D004586:Electrophoresis; D008422:Materials Testing; D019736:Prostheses and Implants; D013314:Stress, Mechanical; D013499:Surface Properties
D001672:Biocompatible Materials; D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; C485830:tetracalcium phosphate; C485838:calcium phosphate, monobasic, anhydrous; C020243:calcium phosphate; C485829:calcium phosphate, dibasic, anhydrous