title: Comparison of ketoprofen and morphine for post-operative analgesia in orthopaedic patients.
abstract: A prospective, open label, randomized study to compare efficacy of intramuscular administration of ketoprofen and morphine for post operative analgesia in elective orthopaedic surgery was performed in 50 patients. The procedures were open reduction and internal fixation of long bone fractures (26 cases), hip replacement (9 cases) and spinal surgery (15 cases). Pain intensity and pain relief in both groups were evaluated at 1, 3 and 6 hours post-injection. There was no significant differences in pain relief of both groups (P = 0.05). The side effects of intramuscular ketoprofen were encountered in only 8 per cent. Ketoprofen injection is an alternative for post operative pain relief.
authors.affiliation: Institute of Orthopaedics, Lerdsin Hospital, Bangkok, Thailand.
authors.forename: P
authors.initials: P
authors.lastname: Vathana
authors.forename: C
authors.initials: C
authors.lastname: Pakpianpairoj
authors.forename: T
authors.initials: T
authors.lastname: Prasartritha
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000701:Analgesics, Opioid / Q000008:administration & dosage*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D007660:Ketoprofen / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009020:Morphine / Q000008:administration & dosage*; D009985:Orthopedics; D010147:Pain Measurement; D010149:Postoperative Pain / Q000517:prevention & control*; D011446:Prospective Studies; D011897:Random Allocation
chemical_list: D000701:Analgesics, Opioid; D000894:Anti-Inflammatory Agents, Non-Steroidal; D009020:Morphine; D007660:Ketoprofen