title: The kinetics of bioaccumulation of zinc, copper, lead and cadmium by oysters (Crassostrea iredalei and C. belcheri) under tropical field conditions.
abstract: A study on the kinetics of accumulation and depuration of Zn, Cu, Pb and Cd by the oysters (Crassostrea iredalei and Crassostrea belcheri) cultured at two locations in the Merbok Estuary, Malaysia was conducted. A first-order kinetic model was employed to fit the experimental data in order to estimate the rate constants for uptake and elimination processes and to predict the bioconcentration factors (BCF). Among the four metals studied, only the Zn accumulation process could not be modelled using first-order kinetics. The elimination rate constants estimated from depuration data for C. iredalei are found to be much greater than those from accumulation data. The results suggest that the values of kinetic parameters and BCFs derived under conditions of both aqueous and dietary exposure are probably more site- than species-specific.
authors.affiliation: School of Chemical Sciences, Universiti Sains Malaysia, Penang, Malaysia.
authors.forename: P E
authors.initials: PE
authors.lastname: Lim
authors.forename: C K
authors.initials: CK
authors.lastname: Lee
authors.forename: Z
authors.initials: Z
authors.lastname: Din
mesh_terms: D000818:Animals; D002104:Cadmium / Q000493:pharmacokinetics; D003300:Copper / Q000493:pharmacokinetics; D005506:Food Contamination; D006801:Humans; D007700:Kinetics; D007854:Lead / Q000493:pharmacokinetics; D008296:Malaysia; D019216:Metals, Heavy / Q000493:pharmacokinetics*; D008954:Models, Biological; D010125:Ostreidae / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000493:pharmacokinetics*; D015032:Zinc / Q000493:pharmacokinetics
chemical_list: D019216:Metals, Heavy; D014874:Water Pollutants, Chemical; D002104:Cadmium; D007854:Lead; D003300:Copper; D015032:Zinc