title: Cancrum oris (noma) in a patient with acute lymphoblastic leukaemia. A complication of chemotherapy induced neutropenia.
abstract: Cancrum oris (noma) has been most commonly described in malnourished debilitated children with poor oral hygiene following systemic childhood infections such as measles, pertussis or scarlet fever. We describe a patient who developed this condition during a period of profound neutropenia following cytotoxic chemotherapy for acute lymphoblastic leukaemia.
authors.affiliation: Department of Pathology, and Microbiology, University of the West Indies, Mona, Jamaica.
authors.forename: D C
authors.initials: DC
authors.lastname: Brady-West
authors.forename: L
authors.initials: L
authors.lastname: Richards
authors.forename: J
authors.initials: J
authors.lastname: Thame
authors.forename: F
authors.initials: F
authors.lastname: Moosdeen
authors.forename: A
authors.initials: A
authors.lastname: Nicholson
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D005734:Gangrene; D006801:Humans; D007710:Klebsiella Infections / Q000139:chemically induced / Q000473:pathology; D007711:Klebsiella pneumoniae; D015459:Leukemia-Lymphoma, Adult T-Cell / Q000188:drug therapy* / Q000473:pathology; D008046:Lip / Q000473:pathology; D009061:Mouth Mucosa / Q000473:pathology; D009503:Neutropenia / Q000139:chemically induced* / Q000473:pathology; D009625:Noma / Q000139:chemically induced* / Q000473:pathology; D011552:Pseudomonas Infections / Q000139:chemically induced / Q000473:pathology; D011550:Pseudomonas aeruginosa; D012074:Remission Induction; D013203:Staphylococcal Infections / Q000139:chemically induced / Q000473:pathology