Relation of left atrial spontaneous echo contrast with prethrombotic state in atrial fibrillation associated with systemic hypertension, idiopathic dilated cardiomyopathy, or no identifiable cause (lone).
To investigate the association of left atrial (LA) spontaneous echo contrast with the hemostatic state in nonrheumatic atrial fibrillation (AF), we examined the plasma levels of prothrombin fragment 1+2 and fibrinopeptide A in 73 patients with chronic nonrheumatic AF undergoing transesophageal echocardiography and 38 age-matched normal subjects. The results support the theory that LA spontaneous echo contrast in nonrheumatic AF is associated with a hypercoagulable state, especially in patients with marked LA spontaneous echo contrast.
Tsai
L M
LM
Department of Internal Medicine, National Cheng Kung University Medical College and Hospital, Tainan, Taiwan, Republic of China.
Chen
J H
JH
Tsao
C J
CJ
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001281:Atrial Fibrillation / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D002312:Cardiomyopathy, Hypertrophic / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D016022:Case-Control Studies; D017548:Echocardiography, Transesophageal; D005260:Female; D005344:Fibrinopeptide A / Q000378:metabolism*; D006325:Heart Atria / Q000000981:diagnostic imaging*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D010446:Peptide Fragments / Q000378:metabolism*; D011498:Protein Precursors / Q000378:metabolism*; D011516:Prothrombin / Q000378:metabolism*; D013923:Thromboembolism / Q000517:prevention & control*
D010446:Peptide Fragments; D011498:Protein Precursors; D005344:Fibrinopeptide A; C029733:prothrombin fragment 1; C044183:prothrombin fragment 2; D011516:Prothrombin