title: HTLV-I associated sicca syndrome in Guadeloupe: lack of relation with a peculiar encoding sequence of surface envelope glycoprotein.
abstract: We previously reported a strikingly high prevalence of ocular diseases in HTLV-I infected patients in Guadeloupe (Caribbean basin). We sequenced the surface envelope encoding region of 7 HTLV-I proviruses from guadeloupean patients (5 with sicca syndrome, 2 with TSP/HAM). No relation between sequence and disease was observed. These 7 sequences are the first described from Guadeloupe.
authors.affiliation: INSERM, Unité 328, Université Victor Segalen-Bordeaux 2.
authors.forename: A
authors.initials: A
authors.lastname: Georges-Gobinet
authors.forename: D
authors.initials: D
authors.lastname: Moynet
authors.forename: C
authors.initials: C
authors.lastname: Hajjar
authors.forename: S
authors.initials: S
authors.lastname: Sainte-Foie
authors.forename: J
authors.initials: J
authors.lastname: Savin
authors.forename: B
authors.initials: B
authors.lastname: Guillemain
mesh_terms: D004279:DNA, Viral; D015686:Gene Products, env / Q000235:genetics*; D019430:Guadeloupe; D015368:Human T-lymphotropic virus 1 / Q000235:genetics*; D006801:Humans; D015493:Paraparesis, Tropical Spastic / Q000821:virology*; D015682:Retroviridae Proteins, Oncogenic / Q000235:genetics*; D012859:Sjogren's Syndrome / Q000821:virology*
chemical_list: D004279:DNA, Viral; D015686:Gene Products, env; D015682:Retroviridae Proteins, Oncogenic; C055266:gp46 protein, Human T-cell leukemia virus type I