title: Comparison of radiation dose from intravenous urography and 99Tcm DMSA scintigraphy in children.
abstract: Intravenous urography (i.v.u.) and 99Tcm DMSA scintigraphy are possible alternative diagnostic techniques in paediatric renal investigation. Radiation dose comparisons between them have been complicated in the past by the lack of paediatric data. In this study, evaluations relevant to children are used to compare estimates of effective dose from the two techniques. For the radiographic procedures, standard operating parameters and representative age-dependent values of entrance surface dose were established from recent literature. Conversion factors relating effective dose to entrance surface dose and dose-area product are presented and used to obtain values of effective dose for single radiographs of abdomen, kidneys and pelvis. Suggested i.v.u. procedures consisting of four ("minimum") or eight ("average") radiographs were adopted to derive the effective dose for full i.v.u. examinations. 99Tcm DMSA dose estimates, taken from our published work using an administered activity schedule based on body surface area, are almost constant at about 1 mSv for all children. In comparison, mean i.v.u. doses based on the "average" number of radiographs are similar to DMSA doses for infants (< 1 year) but may be twice as high for older children. Although the differences between procedures at this level of dose do not in themselves provide grounds for preference, when coupled with the lower diagnostic sensitivity of i.v.u. they suggest limitations of this procedure for detection of a renal scar.
authors.affiliation: Department of Radiology, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: T
authors.initials: T
authors.lastname: Smith
authors.forename: I
authors.initials: I
authors.lastname: Gordon
authors.forename: J P
authors.initials: JP
authors.lastname: Kelly
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007668:Kidney / Q000000981:diagnostic imaging; D010388:Pelvis / Q000000981:diagnostic imaging; D011829:Radiation Dosage; D011860:Radiography, Abdominal; D011877:Radionuclide Imaging; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D014567:Urography
chemical_list: D019783:Technetium Tc 99m Dimercaptosuccinic Acid