title: Assessment of preterm infants in the intensive-care unit to predict cerebral palsy and motor outcome at 6 years.
abstract: One hundred and fifty-three infants were assessed by a method specific to preterm infants and appropriate to the intensive-care nursery environment. The presence or absence of six atypical features (coarse jitters, dominant asymmetrical tonic neck reflex, paucity of movement, 'contradictory' development, hypotonia, or hypertonia) resulted in neonatal classification. There were 116 'usual' (an absence of atypical features with progressive development), 26 'unusual' (a transient occurrence of any atypical feature), and 11 'suspect' (dominance of one or more atypical features). At 6 years of age the motor subsystems of balance, coordination, fine and gross motor, and associated movements were assessed. Nine of 11 children with cerebral palsy had neonatal categories of 'suspect' (7) and 'unusual' (2), of the remaining four other 'suspect' children, two failed two motor subsystems and two failed motor items. A 'usual' neonatal assessment predicted normal motor outcome for 72 of 116 (62%) whereas a 'suspect' assessment predicted major motor dysfunction for seven of 11 of the children.
authors.affiliation: Neurology and Perinatology, King George V Hospital, Sydney, NSW, Australia.
authors.forename: J L
authors.initials: JL
authors.lastname: Lacey
authors.forename: D J
authors.initials: DJ
authors.lastname: Henderson-Smart
mesh_terms: D002547:Cerebral Palsy / Q000175:diagnosis*; D002648:Child; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D019102:Infant, Very Low Birth Weight; D015931:Intensive Care, Neonatal; D009460:Neurologic Examination; D011237:Predictive Value of Tests; D011446:Prospective Studies; D011596:Psychomotor Disorders / Q000175:diagnosis*; D013997:Time Factors