Heparin cofactor II: a new marker for pre-eclampsia.
The plasma levels of heparin cofactor II were determined in pregnant women who were either normotensive, or had essential hypertension, gestational hypertension or pre-eclampsia during the third trimester and 72 h after delivery. Heparin cofactor II levels in the pre-eclampsia group were depressed. The clinical relevance of this finding is the potential utility of heparin cofactor II plasma levels in the differential diagnostic between non-proteinuric hypertension and pre-eclampsia.
Bellart
J
J
Unitat de Medicina Materno-fetal, Hospital Universitari de Tarragona Joan XXIII, Universitat Rovira i Virgili, Spain. jbellarta@meditex.es
Gilabert
R
R
Cabero
L
L
Fontcuberta
J
J
Monasterio
J
J
Miralles
R M
RM
D000328:Adult; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D003937:Diagnosis, Differential; D005260:Female; D015844:Heparin Cofactor II / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000150:complications; D011225:Pre-Eclampsia / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D011237:Predictive Value of Tests; D011247:Pregnancy
D015415:Biomarkers; D015844:Heparin Cofactor II