title: [Evolution of the prevalence of hepatitis A antibody in Seville].
abstract: OBJECTIVE
  To find the evolution of the prevalence of the Hepatitis-A antibody in Sevilla.
  
  
  METHODS
  Observational study of a crossover type. Comparison of results in 1995 with those from a similar study in 1981.
  
  
  METHODS
  Health Area covered by Sevilla's University Hospital Virgen del Rocío.
  
  
  METHODS
  Aliquots of serum from patients without Hepatitis were obtained from the hospital's clinical analysis laboratories.
  
  
  RESULTS
  The sera were analysed in the Nuclear Medicine laboratory of the HUVR. 37.96% (62.74% in 1981) of the individuals surveyed were HA-positive. Prevalence increased with age: in the over-24s it was over 75% (90% in 1981). The differences between the two sets of results was significant (p < 0.001).
  
  
  CONCLUSIONS
  Hepatitis-A infection is becoming less common in Andalusia, which can now be considered a low-incidence area.
authors.affiliation: Hospital Universitario Virgen del Rocío Sevilla.
authors.forename: F
authors.initials: F
authors.lastname: Rivera
authors.forename: J
authors.initials: J
authors.lastname: Ruiz
authors.forename: F
authors.initials: F
authors.lastname: García de Pesquera
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D018592:Cross-Over Studies; D003430:Cross-Sectional Studies; D006506:Hepatitis A / Q000453:epidemiology*; D035922:Hepatitis A Antibodies; D006508:Hepatitis Antibodies / Q000032:analysis*; D006507:Hepatovirus / Q000276:immunology*; D006801:Humans; D015994:Incidence; D007223:Infant; D013030:Spain / Q000453:epidemiology
chemical_list: D035922:Hepatitis A Antibodies; D006508:Hepatitis Antibodies
vernacular_title: Evolución de la prevalencia del anticuerpo antihepatitis A en Sevilla.