Effect of pulmonary artery stenoses on the cardiopulmonary response to exercise following repair of tetralogy of Fallot.
Data from exercise tests, echocardiograms, and lung perfusion scans were analyzed to determine whether the excessive minute ventilation (VE) often encountered among patients with tetralogy of Fallot is due to ventilation-perfusion mismatch secondary to branch pulmonary artery stenoses. Patients with branch PA stenoses had lower peak oxygen consumptions and higher VE during exercise than did patients without stenoses, and a strong correlation existed between the degree of pulmonary blood flow maldistribution on lung perfusion scan and the amount of excessive VE during exercise.
Rhodes
J
J
Division of Pediatric Cardiology, Boston, Massachusetts 02111, USA.
Dave
A
A
Pulling
M C
MC
Geggel
R L
RL
Marx
G R
GR
Fulton
D R
DR
Hijazi
Z M
ZM
D000293:Adolescent; D000328:Adult; D002648:Child; D015150:Echocardiography, Doppler; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D011652:Pulmonary Circulation; D011666:Pulmonary Valve Stenosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology*; D013771:Tetralogy of Fallot / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery; D014692:Ventilation-Perfusion Ratio