title: [A rare biphasic pulmonary tumor, carcinosarcoma. A separate entity or differentiation variant of spindle-cell carcinoma?].
abstract: We report a case of pulmonary carcinosarcoma. Surgery is required for this rare mixed type, biphasic tumor. It is generally considered to be a malignant formation issuing from a single cell line but with a two-way differentiation into epithelial and conjunctive components. There is a differentiation continuum between spindle-cell carcinomas (also called monophasic sarcomatoid carcinoma) and carcinosarcoma (or biphasic sarcomatoid carcinoma) leading to debate concerning the immunohistochemical and ultrastructural features.
authors.affiliation: Service de Pneumologie, Hôpital Pontchaillou, CHRU Rennes.
authors.forename: J C
authors.initials: JC
authors.lastname: Renaud
authors.forename: H
authors.initials: H
authors.lastname: Léna
authors.forename: S
authors.initials: S
authors.lastname: Caulet-Maugendre
authors.forename: H
authors.initials: H
authors.lastname: Corbineau
authors.forename: C
authors.initials: C
authors.lastname: Belleguic
authors.forename: B
authors.initials: B
authors.lastname: Desrues
authors.forename: P
authors.initials: P
authors.lastname: Delaval
mesh_terms: D002296:Carcinosarcoma / Q000145:classification / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008175:Lung Neoplasms / Q000145:classification / Q000473:pathology* / Q000601:surgery; D008297:Male; D008875:Middle Aged
vernacular_title: Une tumeur pulmonaire biphasique rare, le carcinosarcome. Entité à part entière ou variante de différenciation du carcinome à cellules fusiformes?