title: [Cephalosporins in the treatment of children with oncohematologic diseases].
abstract: Clinical efficacy of 3rd generation cephalosporins i.e. oral cefpodoxime and parenteral ceftriaxone was studied in the treatment of children with oncohematologic pathology. Cefpodoxime proved to be efficient in cases of moderate infectious complications in regard to the respiratory tracts. The oral administration of the drug provided its usage in outpatients. Ceftriaxone had a favourable effect in the treatment of children with more severe processes as a rule at the background of agranulocytosis and a lower immune response often with a tendency to generalization. No side effects of the cephalosporins were observed.
authors.affiliation: Russian State Medical University, Moscow.
authors.forename: N V
authors.initials: NV
authors.lastname: Nepokul'chitskaia
authors.forename: A M
authors.initials: AM
authors.lastname: Timakov
authors.forename: K L
authors.initials: KL
authors.lastname: Kondratchik
authors.forename: T Zh
authors.initials: TZh
authors.lastname: Makhortykh
authors.forename: I S
authors.initials: IS
authors.lastname: Tarasova
authors.forename: T A
authors.initials: TA
authors.lastname: Erina
mesh_terms: D000284:Administration, Oral; D000380:Agranulocytosis / Q000209:etiology; D000741:Anemia, Aplastic / Q000150:complications* / Q000188:drug therapy; D015296:Ceftizoxime / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D002443:Ceftriaxone / Q000008:administration & dosage / Q000627:therapeutic use*; D002511:Cephalosporins / Q000008:administration & dosage / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D019337:Hematologic Neoplasms / Q000150:complications* / Q000503:physiopathology; D006801:Humans; D007274:Injections, Intraperitoneal; D009894:Opportunistic Infections / Q000188:drug therapy* / Q000209:etiology; D012141:Respiratory Tract Infections / Q000188:drug therapy* / Q000209:etiology; D016896:Treatment Outcome; D000097623:Cefpodoxime
chemical_list: D015296:Ceftizoxime; D002443:Ceftriaxone; D002511:Cephalosporins; D000097623:Cefpodoxime
vernacular_title: Primenenie tsefalosporinov u deteĭ s onkogematologicheskimi zabolevaniiami.