MRI of hyperpolarized 3He gas in human paranasal sinuses.
In this study, MRI of hyperpolarized 3He gas in human paranasal sinuses is presented. Helium images were obtained at 1.5 T, using a surface coil and a 2D, fast gradient-echo sequence with a nominal constant flip angle of 12 degrees. Coronal images of 20-mm thick slices were generated and compared with proton images of the corresponding sections. The images enable visualization of the paranasal sinuses and the nasal cavity, suggesting a potential use of this method not only in identifying the anatomical configuration of these pneumatic spaces, but also in assessing sinus ventilation.
Rizi
R R
RR
Department of Radiology, University of Pennsylvania, Philadelphia 19104-6281, USA.
Dimitrov
I E
IE
Thompson
A
A
Jones
G
G
Gentile
T R
TR
Ishii
M
M
Reddy
R
R
Schnall
M D
MD
Leigh
J S
JS
D000328:Adult; D003287:Contrast Media; D006371:Helium; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation; D007554:Isotopes; D008279:Magnetic Resonance Imaging / Q000295:instrumentation; D008297:Male; D009296:Nasal Cavity / Q000033:anatomy & histology; D010256:Paranasal Sinuses / Q000033:anatomy & histology*; D012123:Pulmonary Ventilation / Q000502:physiology; D012016:Reference Values; D012680:Sensitivity and Specificity
D003287:Contrast Media; D007554:Isotopes; D006371:Helium