title: Post-keratoplasty endophthalmitis caused by Proteus mirabilis.
abstract: A diabetic patient who underwent a triple procedure (penetrating keratoplasty, cataract extraction and posterior chamber intraocular lens implantation), developed endophthalmitis caused by Proteus mirabilis. The source of infection was the infected donor cornea, which was imported from Sri Lanka. The organism was resistant to gentamicin, which was the only antibiotic present in the storage medium. On top of an aggressive antibiotic treatment regime (topical, systemic and intravitreal), exchange of the infected with a fresh corneal graft and pars plana vitrectomy were performed. The patient had a speedy recovery and the visual outcome was 20/40 two and a half years after the incident. To our knowledge, post-keratoplasty endophthalmitis caused by P. mirabilis has never been reported in the literature. We report herein such a case with good visual outcome. Newer storage medium, such as Optisol GS, might have a role in preventing keratoplasty-related infection.
authors.affiliation: Department of Ophthalmology & Visual Sciences, Chinese University of Hong Kong, Prince of Wales Hospital Shatin, N. T., Hong Kong. dennislam@cuhk.edu.hk
authors.forename: D S
authors.initials: DS
authors.lastname: Lam
authors.forename: A K
authors.initials: AK
authors.lastname: Kwok
authors.forename: S
authors.initials: S
authors.lastname: Chew
mesh_terms: D000368:Aged; D002387:Cataract Extraction; D009877:Endophthalmitis / Q000382:microbiology*; D005260:Female; D006801:Humans; D015948:Keratoplasty, Penetrating / Q000009:adverse effects*; D019654:Lens Implantation, Intraocular; D011512:Proteus Infections / Q000635:transmission*; D011513:Proteus mirabilis