title: [Endoscopic ultrasonography in the staging of esophageal cancer. Therapeutic implications].
abstract: Endoscopic ultrasonography (EUS) provides accurate visualization of the different layers of the gastrointestinal wall and surrounding structures, allowing TN staging of tumors prior surgery. The aim of this study was to evaluate the sensitivity, specificity and accuracy of EUS in the staging of esophageal carcinoma as well as its applicability and usefulness in tumors with nontraversable stenoses. EUS was performed in 43 patients with esophageal carcinoma. The technique was carried out with a radial echoendoscope under sedation with i.v. midazolam. Both, the infiltration of the tumor through the layers of the esophageal wall (T staging) and the presence of lymph nodes in different areas (N and M staging) were determined. In cases with nontraversable stenoses, only the proximal tumor margin was assessed by means of EUS. EUS showed T1 stage in only one case and more advanced stages in the remaining patients: T2 (n = 12), T3 (n = 22) and T4 (n = 4). We know the outcome of 28 patients, 14 of whom underwent surgery. In these patients, the sensitivity for T and N staging was 86% and 92% respectively, and the accuracy 86% in both. Both, T and N, were overstaged in one case (7%) and understaged in another (7%). The tumor caused nontraversable stenoses in 59% of patients (n = 26). In 4 patients the staging could not be assessed with sufficient reliability. In the subgroup of patients with nontraversable stenoses who underwent surgery, the accuracy of EUS when comparing with histopathology was 80%. Endoscopic ultrasonography has a high sensitivity and accuracy in the staging of esophageal tumors even in cases with nontraversable stenoses.
authors.affiliation: Sección de Endoscopia Digestiva, Hospital Clínic i Provincial, Barcelona.
authors.forename: A
authors.initials: A
authors.lastname: Ginès
authors.forename: J M
authors.initials: JM
authors.lastname: Bordas
authors.forename: J
authors.initials: J
authors.lastname: Llach
authors.forename: F
authors.initials: F
authors.lastname: Mondelo
authors.forename: J
authors.initials: J
authors.lastname: Fernández
authors.forename: A
authors.initials: A
authors.lastname: Castells
authors.forename: M
authors.initials: M
authors.lastname: Pera
authors.forename: L
authors.initials: L
authors.lastname: Grande
authors.forename: J M
authors.initials: JM
authors.lastname: Piqué
mesh_terms: D000368:Aged; D019160:Endosonography; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012680:Sensitivity and Specificity
vernacular_title: Ultrasonografía endoscópica y estudio de extensión del carcinoma de esófago. Implicaciones terapéuticas.