Cerebral venous thrombosis in pregnancy: the role of protein S deficiency.
We report a 20 year-old, 28 week-pregnant woman, who developed superior sagittal sinus thrombosis, associated with a decreased free protein S level. Her father, who had been a stroke victim, had also significantly lower level of protein S. In very rare cases, a congenital or acquired protein S deficiency leads to cerebral venous thrombosis. The detection of such abnormalities has major practical consequences for the long-term management of patients to prevent further thrombotic episodes.
Gökçil
Z
Z
Department of Neurology, Gülhane Medical School, Ankara, Turkey.
Odabasi
Z
Z
Vural
O
O
Yardim
M
M
D000328:Adult; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic; D018455:Protein S Deficiency / Q000503:physiopathology*; D012851:Sinus Thrombosis, Intracranial / Q000175:diagnosis / Q000503:physiopathology*