title: A novel method of assessing carcinoma cell proliferation by biophoton emission.
abstract: Changes in the emission intensities of ultraweak biophoton emission during the cell proliferation of human carcinoma cell culture (TE9 cell line) were detected using a highly sensitive and low noise measurement apparatus coupled with a flow culture system. In the sampling period of 93 h, the biophoton emission intensity from the culture followed a similar course as that of the growth curve. Spectral analysis of the biophoton emission from the cell culture demonstrated a significant peak at around 530 nm. Our results suggest that the emission intensity mainly depends on the cell population and that this noninvasive technique has a potential role in cancer diagnosis.
authors.affiliation: Biophotonics Information Laboratories, Yamagata Advanced Technology, Research & Development Center, Matsuei, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Takeda
authors.forename: Y
authors.initials: Y
authors.lastname: Tanno
authors.forename: M
authors.initials: M
authors.lastname: Kobayashi
authors.forename: M
authors.initials: M
authors.lastname: Usa
authors.forename: N
authors.initials: N
authors.lastname: Ohuchi
authors.forename: S
authors.initials: S
authors.lastname: Satomi
authors.forename: H
authors.initials: H
authors.lastname: Inaba
mesh_terms: D002277:Carcinoma / Q000473:pathology*; D002455:Cell Division; D004938:Esophageal Neoplasms / Q000473:pathology*; D006801:Humans; D008163:Luminescent Measurements; D017785:Photons