Hereditary hypotrichosis simplex.
Hypotrichosis is a relatively common feature of a number of complex hereditary syndromes. However, the isolated variant, called hereditary hypotrichosis simplex (HHS), is especially uncommon. We present a Spanish family with 8 of 19 persons covering 4 generations affected by HHS. No associated ectodermal or other defects were noted. The pedigree was compatible with an autosomal dominant inheritance with variable penetrance.
Just
M
M
Department of Dermatology, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain.
Ribera
M
M
Fuente
M J
MJ
Bielsa
I
I
Ferrándiz
C
C
D002648:Child; D003937:Diagnosis, Differential; D006801:Humans; D007039:Hypotrichosis / Q000175:diagnosis* / Q000235:genetics*; D008297:Male; D010375:Pedigree