title: Maintenance of growth in cystic fibrosis despite reduction in pancreatic enzyme supplementation.
abstract: Twenty one children with cystic fibrosis were advised to decrease their pancreatic enzyme supplement (PES) dose to less than 10,000 units lipase/kg/day. Mean PES dosage was significantly decreased in 15 patients from 18,380 to 8647 units lipase/kg/day. There were no significant changes in energy or fat intake, but there were significant increases in weight SD score, height SD score, and weight/height ratio.
authors.affiliation: Department of Child Health, University Hospital of Wales, Heath Park, Cardiff.
authors.forename: J
authors.initials: J
authors.lastname: Lowdon
authors.forename: M C
authors.initials: MC
authors.lastname: Goodchild
authors.forename: H C
authors.initials: HC
authors.lastname: Ryley
authors.forename: I J
authors.initials: IJ
authors.lastname: Doull
mesh_terms: D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000188:drug therapy* / Q000378:metabolism / Q000503:physiopathology; D004334:Drug Administration Schedule; D005243:Feces / Q000737:chemistry; D005500:Follow-Up Studies; D006128:Growth / Q000187:drug effects*; D006801:Humans; D008049:Lipase / Q000008:administration & dosage*; D008055:Lipids / Q000032:analysis
chemical_list: D008055:Lipids; D008049:Lipase