title: [Structural and functional characteristics of angiotensin converting enzyme].
abstract: The structure and functions in various tissues of angiotensin converting enzyme (ACE, peptidyl dipeptidase A), a key enzyme in blood pressure regulation, are reviewed. The similarity and differences of two homologous catalytically active N- and C-domains of the ACE molecule are discussed, and different biological functions of these domains are suggested. Natural active single-domain forms of ACE are characterized.
authors.affiliation: Institute of Biomedical Chemistry, Russian Academy of Medical Sciences, Moscow, Russia.
authors.forename: Iu E
authors.initials: IuE
authors.lastname: Eliseeva
mesh_terms: D000595:Amino Acid Sequence; D001826:Body Fluids / Q000201:enzymology; D004730:Endothelium, Vascular / Q000166:cytology / Q000201:enzymology; D004847:Epithelial Cells / Q000201:enzymology; D005347:Fibroblasts / Q000201:enzymology; D006801:Humans; D007962:Leukocytes / Q000201:enzymology; D008969:Molecular Sequence Data; D009474:Neurons / Q000201:enzymology; D010455:Peptides / Q000737:chemistry*; D007703:Peptidyl-Dipeptidase A / Q000737:chemistry* / Q000502:physiology*; D013379:Substrate Specificity
chemical_list: D010455:Peptides; D007703:Peptidyl-Dipeptidase A
vernacular_title: Strukturno-funktsional'nye osobennosti angiotensinprevrashchaiushchego fermenta.