[Effects of prolonged gamma irradiation and hypoxia on bioelectrical activity of myocardial cells].
It was established that prolonged gamma-irradiation of rats leads to the decrease of amplitude and duration of action potentials of right atrial cells, attenuation of the dependence of these electrophysiological characteristics upon the stimulation frequency, depression of the interval of cardiomyocytes reaction on the hypoxia. The revealed post-radiation changes determine the reduction of function resistance of heart cells bioelectrical activity and promote the initiation of arrhythmias.
Lobanok
L M
LM
Institute of Radiobiology, National Academy of Science of Belarus, Minsk.
Malykhina
A P
AP
D000200:Action Potentials; D000818:Animals; D001145:Arrhythmias, Cardiac / Q000209:etiology; D003627:Data Interpretation, Statistical; D004558:Electric Stimulation; D004594:Electrophysiology; D006321:Heart / Q000503:physiopathology*; D006325:Heart Atria / Q000166:cytology / Q000503:physiopathology; D000860:Hypoxia / Q000503:physiopathology*; D066298:In Vitro Techniques; D008297:Male; D009206:Myocardium / Q000166:cytology*; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000503:physiopathology*; D051381:Rats; D012984:Software; D013997:Time Factors
Effekty prolongirovannogo gamma-oblucheniia i gipoksii na bioélektricheskuiu aktivnost' kletok miokarda.