title: Regulation of megakaryocytopoiesis and platelet production: lessons from animal models.
authors.affiliation: Department of Molecular Oncology, Genentech Inc., South San Francisco, California 94080, USA.
authors.forename: F J
authors.initials: FJ
authors.lastname: de Sauvage
authors.forename: J L
authors.initials: JL
authors.lastname: Villeval
authors.forename: R A
authors.initials: RA
authors.lastname: Shivdasani
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000378:metabolism*; D002454:Cell Differentiation / Q000502:physiology; D004195:Disease Models, Animal; D005786:Gene Expression Regulation / Q000235:genetics; D006410:Hematopoiesis / Q000502:physiology*; D006801:Humans; D008533:Megakaryocytes / Q000502:physiology*; D051379:Mice; D018345:Mice, Knockout; D009363:Neoplasm Proteins; D011518:Proto-Oncogene Proteins / Q000502:physiology; D018121:Receptors, Cytokine; D053628:Receptors, Thrombopoietin; D013926:Thrombopoietin / Q000502:physiology / Q000627:therapeutic use
chemical_list: D009363:Neoplasm Proteins; D011518:Proto-Oncogene Proteins; D018121:Receptors, Cytokine; D053628:Receptors, Thrombopoietin; C082218:MPL protein, human; D013926:Thrombopoietin