[Study of the secretion of P substance, neurotensin and somatostatin in healthy adults].
OBJECTIVE
A study in humans of the profile of physiologic secretion, basal and postprandial of three gastrointestinal peptides has been carried out.


METHODS
20 healthy subjects were studied (9 women and 11 men); any previous digestive pathology has not been included. The study was carried out by determining P substance, neurotensin and somatostatin in plasma by means of RIA I125. The subjects were studied in basal conditions of fasting and the samples were taken at 30, 60 and 90 minutes intervals after the oral intake of a semi-liquid preparation made up of the three immediate principles.


RESULTS
It shows the secretion curve of the three gastrointestinal peptides, in a global way and also in relation to sex, age and body weight.
Ortega López
D
D
Servicio de Cirugía General I, Hospital Universitario San Carlos, Madrid.
Martínez Sarmiento
J
J
Borque
M
M
Fernández
D
D
Sobrino
J A
JA
Hernández
C
C
Alvarez
M
M
Alvarez Fernández-Represa
J
J
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009496:Neurotensin / Q000378:metabolism*; D012016:Reference Values; D013004:Somatostatin / Q000378:metabolism*; D013373:Substance P / Q000378:metabolism*
D013373:Substance P; D009496:Neurotensin; D013004:Somatostatin
Estudio de la secreción de sustancia P, neurotensina y somatostatina en adultos sanos.