title: [Chronic exposure to environmental lead in Chilean infants].
abstract: BACKGROUND
  In Chile, there are several sources of environmental lead exposure. However, the few studies about lead levels in Chilean infants, do not allow to establish the prevalence of high lead levels in this population.
  
  
  OBJECTIVE
  To measure blood lead levels in nursing infants, living in rural and urban areas, from birth until two years of age.
  
  
  METHODS
  Newborns from public maternity hospitals in Santiago and a rural area were selected for the study. An umbilical cord blood sample was obtained at birth and venous blood samples thereafter, every 6 months until the age of 24 months. Lead levels were measured by atomic absorption spectrophotometry. Atmospheric lead was measured simultaneously every week in Santiago and the rural area.
  
  
  RESULTS
  Three hundred twelve children from Santiago and 113 from the rural area completed the 24 months follow-up. The mean lead exposure for infants living in Santiago and in the rural area was 1.23 +/- 0.66 and 0.19 +/- 0.15 micrograms/m3 respectively (p < 0.001). Mean blood levels were always higher in infants from Santiago, compared to those from the rural area. At 24 months, 4.5% of children from Santiago and 0.7% of children from the rural area had blood lead levels over 10 micrograms/dl. Significant risk factors for high lead levels were recent painting of the house where the infant lives, eating soil, biting banisters and familiar labor exposure to lead.
  
  
  CONCLUSIONS
  Infants living in an urban area and exposed to increased atmospheric lead levels have higher blood lead levels than infants living in a rural area.
authors.affiliation: Universidad de Chile, Facultad de Medicina, Santiago, Chile.
authors.forename: P
authors.initials: P
authors.lastname: Frenz
authors.forename: J
authors.initials: J
authors.lastname: Vega
authors.forename: N
authors.initials: N
authors.lastname: Marchetti
authors.forename: J
authors.initials: J
authors.lastname: Torres
authors.forename: E
authors.initials: E
authors.lastname: Kopplin
authors.forename: I
authors.initials: I
authors.lastname: Delgado
authors.forename: F
authors.initials: F
authors.lastname: Vega
mesh_terms: D000393:Air Pollutants / Q000097:blood*; D000704:Analysis of Variance; D002675:Child, Preschool; D002677:Chile; D004781:Environmental Exposure; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007854:Lead / Q000097:blood*; D012307:Risk Factors
chemical_list: D000393:Air Pollutants; D007854:Lead
vernacular_title: Exposición crónica a plomo ambiental en lactantes chilenos.