[Transplantation of organic culture of adrenal grand cortical substance in the treatment of post-adrenalectomy hypocorticoidism].
The organ culture transplantation of the adrenals cortical substance of a newborn piglets was applied while 94 patients treatment to whom total adrenalectomy for Itsenko--Cushing disease was done. Significant lowering of the substitutional hormonal therapy (steroid preparations) dosage was permitted due to the noted improvement of hypocorticism clinical course and an organism hormonal security indexes. The clinical effect duration is 6-9 months. The methods physiologically substantiated, technically simple, economically advantageous, do not cause the side effects.
Sichinava
R M
RM
Rybakov
S I
SI
Komissarenko
I V
IV
Turchin
I S
IS
D000293:Adolescent; D000311:Adrenal Glands / Q000196:embryology / Q000601:surgery / Q000637:transplantation; D000309:Adrenal Insufficiency / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery*; D000315:Adrenalectomy / Q000009:adverse effects*; D000324:Adrenocorticotropic Hormone / Q000172:deficiency*; D000328:Adult; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003348:Cortisone / Q000627:therapeutic use; D003480:Cushing Syndrome / Q000601:surgery*; D005260:Female; D016332:Fetal Tissue Transplantation; D006801:Humans; D008297:Male; D013552:Swine
D000893:Anti-Inflammatory Agents; D000324:Adrenocorticotropic Hormone; D003348:Cortisone
Transplantatsiia organnoĭ kul'tury korkovogo veshchestva nadpochechnikov v lechenii postadrenaléktomicheskogo gipokortitsizma.