Successful allogeneic bone marrow transplant for chronic myeloid leukaemia despite previous interferon-induced cardiomyopathy.
We report a patient with CML who developed a reversible dilated cardiomyopathy with cardiac failure following 10 months of IFN therapy. Despite the previous cardiomyopathy, he tolerated subsequent allogeneic BMT without any adverse cardiac events. Reversible IFN-induced cardiomyopathy should not be considered a contraindication to bone marrow transplantation.
Broady
R
R
Haematology Department, Auckland Hospital, New Zealand.
Hawkins
T
T
Browett
P
P
Palmer
S
S
D000328:Adult; D016026:Bone Marrow Transplantation; D002311:Cardiomyopathy, Dilated / Q000139:chemically induced*; D006801:Humans; D007372:Interferons / Q000009:adverse effects*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000628:therapy*; D008297:Male; D014184:Transplantation, Homologous
D007372:Interferons