title: Serologic profile of some sexually transmitted diseases in women with squamous intraepithelial lesions.
abstract: The purpose of this study consisted of the evaluation of some sexually transmitted diseases in patients with cervical pathology, namely squamous intraepithelial lesions.
  
  
  METHODS
  a prospective study was performed. Patients with an abnormal cervical smear were submitted to colposcopy, directed biopsy and an immunologic assay for Chlamydia, Herpes Simplex Virus (HSV) types 1 and 2, Cytomegalovirus, Treponema pallidum, Hepatitis B and Human Immunodeficiency Virus I and II. The same parameters were evaluated in women with normal cervical cytology in a matched control group. A comparative study was performed evaluating some epidemiological parameters and the referred immunologic assays.
  
  
  RESULTS
  118 patients were separated into four groups. Statistically significant differences were observed in the personal history of fungi infections, as well as Chlamydia and HSV 2 IgM.
  
  
  CONCLUSIONS
  immunologic assays may prove useful in identifying sexually-transmitted diseases, especially Chlamydia and HSV 2 infections, in Human Papillomavirus infected women.
authors.affiliation: Department of Gynecology of the Hospitais da Universidade de Coimbra, Portugal.
authors.forename: C
authors.initials: C
authors.lastname: Gomes
authors.forename: M
authors.initials: M
authors.lastname: Dias
authors.forename: F
authors.initials: F
authors.lastname: Falcao
authors.forename: C
authors.initials: C
authors.lastname: Oliveira
mesh_terms: D000328:Adult; D001707:Biopsy, Needle; D002278:Carcinoma in Situ / Q000453:epidemiology / Q000209:etiology / Q000473:pathology*; D002294:Carcinoma, Squamous Cell / Q000453:epidemiology / Q000209:etiology / Q000473:pathology*; D016009:Chi-Square Distribution; D002690:Chlamydia Infections / Q000150:complications / Q000453:epidemiology / Q000473:pathology; D003127:Colposcopy; D005260:Female; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D009181:Mycoses / Q000150:complications / Q000453:epidemiology / Q000473:pathology; D027383:Papillomaviridae / Q000302:isolation & purification; D030361:Papillomavirus Infections / Q000150:complications / Q000453:epidemiology / Q000473:pathology; D011174:Portugal / Q000453:epidemiology; D011446:Prospective Studies; D012307:Risk Factors; D012698:Serologic Tests; D012749:Sexually Transmitted Diseases / Q000150:complications / Q000453:epidemiology / Q000473:pathology*; D014412:Tumor Virus Infections / Q000150:complications / Q000453:epidemiology / Q000473:pathology; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000209:etiology / Q000473:pathology*; D014626:Vaginal Smears