title: Successful recovery of 14 patients afflicted with full-thickness burns for more than 70 per cent body surface area.
abstract: Fourteen cases suffering full-thickness burns of more than 70 per cent total body surface area (TBSA) have been successfully treated during the last 8 years (1988-1995). Among these patients, 10 cases suffered from burns of more than 90 per cent TBSA. Five cases had full-thickness burns of 80-90 per cent TBSA. Escharectomy, followed by coverage of wounds with a homograft to the lower surface of which, adjacent to the wound bed, microautoskin grafts had been attached was employed to close wounds in the early stages after burn. The remaining non-surgically treated wound was treated by exposure and topical silver sulfadiazine. The temperature and humidity of the ward was controlled by air conditioning and dehumidification. Aggressive excision of eschar and auto-skingrafting was carried out 3 weeks post-injury. Strictly limiting the uncovered wound to less than 5 per cent appeared to be the major effective measure in preventing burn infection.
authors.affiliation: Burn Unit, Nan-fang Hospital, First Military Medical University, Guangzhou, P.R. China.
authors.forename: Y P
authors.initials: YP
authors.lastname: Zhou
authors.forename: Z H
authors.initials: ZH
authors.lastname: Zhou
authors.forename: W M
authors.initials: WM
authors.lastname: Zhou
authors.forename: J L
authors.initials: JL
authors.lastname: Ren
authors.forename: Y H
authors.initials: YH
authors.lastname: Wu
authors.forename: X Z
authors.initials: XZ
authors.lastname: Rong
authors.forename: L
authors.initials: L
authors.lastname: Yang
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local / Q000008:administration & dosage / Q000627:therapeutic use*; D002056:Burns / Q000175:diagnosis / Q000628:therapy*; D002648:Child; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D005260:Female; D005440:Fluid Therapy; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012774:Shock, Traumatic / Q000628:therapy; D012837:Silver Sulfadiazine / Q000008:administration & dosage / Q000627:therapeutic use*; D016038:Skin Transplantation; D014184:Transplantation, Homologous; D015599:Trauma Severity Indices; D016896:Treatment Outcome; D014945:Wound Healing; D014946:Wound Infection / Q000517:prevention & control
chemical_list: D000900:Anti-Bacterial Agents; D000891:Anti-Infective Agents, Local; D012837:Silver Sulfadiazine