[A comparative study on a human model of the in situ absorption by enamel of fluorine obtained from the NaF and Na2PO3F contained in tooth pastes].
A denture model was used in situ in cross experiment to assess fluorine absorption by impaired enamel from toothpastes containing NaF and Na2PO3F. Six toothpastes were used in experiment: two contained NaF, three Na2PO3F, and one contained no fluorine. Twenty-five volunteers participated in experiment, who were fitted with dentures with sites of impaired enamel located close to each other. Each participant in the experiment was to accidentally clean his or her teeth with one of the pastes three times daily for two weeks. Then the enamel specimens were removed and analysed for fluorine content. The experiment lasted till each volunteer spent all the six pastes offered. The results indicated a much higher efficacy of NaF-containing pastes as regards fluorine absorption by impaired enamel than the ones containing Na2PO3F; the presence of decalcinated phosphate did not enhance the activity of Na2PO3F.
Dunipace
A J
AJ
Kelly
S A
SA
Wu
M
M
Stookey
G K
GK
D000042:Absorption; D000328:Adult; D000368:Aged; D000704:Analysis of Variance; D018592:Cross-Over Studies; D003743:Dental Enamel / Q000378:metabolism*; D004311:Double-Blind Method; D005459:Fluorides / Q000493:pharmacokinetics*; D006801:Humans; D008875:Middle Aged; D010710:Phosphates / Q000493:pharmacokinetics*; D012969:Sodium Fluoride / Q000493:pharmacokinetics*; D013997:Time Factors; D014099:Toothbrushing; D014100:Toothpastes / Q000493:pharmacokinetics*
D010710:Phosphates; D014100:Toothpastes; C012980:fluorophosphate; D012969:Sodium Fluoride; D005459:Fluorides
Sravnitel'noe izuchenie na chelovecheskoĭ modeli in situ pogloshcheniia émal'iu ftora, poluchennogo iz NaF i Na2PO3F, soderzhashchikhsia v zubnykh pastakh.