HTLV-I associated sicca syndrome in Guadeloupe: lack of relation with a peculiar encoding sequence of surface envelope glycoprotein.
We previously reported a strikingly high prevalence of ocular diseases in HTLV-I infected patients in Guadeloupe (Caribbean basin). We sequenced the surface envelope encoding region of 7 HTLV-I proviruses from guadeloupean patients (5 with sicca syndrome, 2 with TSP/HAM). No relation between sequence and disease was observed. These 7 sequences are the first described from Guadeloupe.
Georges-Gobinet
A
A
INSERM, Unité 328, Université Victor Segalen-Bordeaux 2.
Moynet
D
D
Hajjar
C
C
Sainte-Foie
S
S
Savin
J
J
Guillemain
B
B
D004279:DNA, Viral; D015686:Gene Products, env / Q000235:genetics*; D019430:Guadeloupe; D015368:Human T-lymphotropic virus 1 / Q000235:genetics*; D006801:Humans; D015493:Paraparesis, Tropical Spastic / Q000821:virology*; D015682:Retroviridae Proteins, Oncogenic / Q000235:genetics*; D012859:Sjogren's Syndrome / Q000821:virology*
D004279:DNA, Viral; D015686:Gene Products, env; D015682:Retroviridae Proteins, Oncogenic; C055266:gp46 protein, Human T-cell leukemia virus type I