title: Greek Cypriot allele and genotype frequencies for Amplitype PM-DQA1 and D1S80 loci.
abstract: A sample from the Greek Cypriot population was typed at seven forensically important PCR-based loci: LDLR, GYPA, HBGG, D7S8, GC, HLA-DQA1, and D1S80. The results showed that all loci meet Hardy-Weinberg expectations and that there is no evidence for association of alleles between loci. Allelic frequency distributions at all loci, except HLA-DQA1 and two D1S80 alleles, were similar to those of U.S. Caucasians. Greek Cypriot population databases have been created and can be used for forensic analyses to estimate the frequency of a multiple locus DNA profile.
authors.affiliation: Cyprus Institute of Neurology and Genetics, DNA Identification Laboratory, Nicosia.
authors.forename: M A
authors.initials: MA
authors.lastname: Cariolou
authors.forename: P
authors.initials: P
authors.lastname: Manoli
authors.forename: M
authors.initials: M
authors.lastname: Christophorou
authors.forename: E
authors.initials: E
authors.lastname: Bashiardes
authors.forename: A
authors.initials: A
authors.lastname: Karagrigoriou
authors.forename: B
authors.initials: B
authors.lastname: Budowle
mesh_terms: D000483:Alleles; D003535:Cyprus; D016172:DNA Fingerprinting / Q000379:methods; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D018740:Genetic Heterogeneity; D005819:Genetic Markers / Q000235:genetics*; D005838:Genotype; D006115:Greece / Q000208:ethnology; D006683:HLA-DQ Antigens / Q000235:genetics*; D059848:HLA-DQ alpha-Chains; D006650:Histocompatibility Testing; D006801:Humans; D016133:Polymerase Chain Reaction; D011933:Reagent Kits, Diagnostic
chemical_list: D005819:Genetic Markers; D006683:HLA-DQ Antigens; D059848:HLA-DQ alpha-Chains; C069050:HLA-DQA1 antigen; D011933:Reagent Kits, Diagnostic