Cancer gene therapy.
Developments in molecular genetics, immunology, molecular and cellular biology, and tumor biology have given rise to the field of cancer gene therapy. Several gene delivery vehicles have been developed and are being examined in clinical trials. Most cancer gene therapy strategies involve introduction of genes to augment existing therapies. An overview is provided on gene delivery vehicles, gene therapy strategies, and cancer gene therapy clinical trials.
Cusack
J C
JC
University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.
Tanabe
K K
KK
D000818:Animals; D002986:Clinical Trials as Topic; D015316:Genetic Therapy; D005822:Genetic Vectors; D006801:Humans; D009369:Neoplasms / Q000628:therapy*