title: Thallium/technetium subtraction scanning for primary hyperparathyroidism: scan sensitivity and effect on operative time.
abstract: Over a ten-year period 26 patients were evaluated by the authors for elevated serum calcium and parathormone levels. All patients were clinically asymptomatic and were referred for parathyroid evaluation following a diagnosis of hypercalcemia made on routine SMA-12 studies. Twenty-four patients had positive thallium/technetium subtraction studies; two were suggestive of bilateral adenomata, one of which was confirmed at surgery. In two patients both thallium/technetium and technetium sestamibi scanning studies were negative. These patients were managed medically without surgical exploration. In all operative cases the patients remained normocalcemic during a six-month follow-up period. Operative times in all cases were less than one hour.
authors.affiliation: Department of Surgery-Otolaryngology, Rutgers Medical School, Piscataway, New Jersey, USA.
authors.forename: J A
authors.initials: JA
authors.lastname: Bergman
authors.forename: R
authors.initials: R
authors.lastname: Pallant
mesh_terms: D000236:Adenoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology; D006961:Hyperparathyroidism / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D010282:Parathyroid Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D011877:Radionuclide Imaging; D012680:Sensitivity and Specificity; D013382:Subtraction Technique; D013667:Technetium; D017256:Technetium Tc 99m Sestamibi; D013794:Thallium Radioisotopes
chemical_list: D013794:Thallium Radioisotopes; D013667:Technetium; D017256:Technetium Tc 99m Sestamibi