Selecting antibacterial agents for the control of surgical infection: mini-review.
An analysis of the recent literature on the control of surgical infections confirms the role of antimicrobial agents which guarantee valid perioperative antisepsis in both clean and clean-contaminated surgery. Current chemotherapy is able to check serious postoperative infectious complications by reducing the risk of septic shock with use of a glycopeptide-aminoglycoside-betalactam combination together with anti-inflammatory drugs.
Periti
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P
Department of Pharmacology, University of Florence, Italy. EIFT@mclink.it
Tonelli
F
F
Mini
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E
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D004359:Drug Therapy, Combination / Q000627:therapeutic use*; D019446:Endotoxemia / Q000517:prevention & control; D006020:Glycopeptides; D006801:Humans; D007769:Lactams; D012772:Shock, Septic / Q000517:prevention & control; D013256:Steroids; D013530:Surgical Wound Infection / Q000188:drug therapy / Q000382:microbiology / Q000517:prevention & control*
D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000891:Anti-Infective Agents, Local; D000893:Anti-Inflammatory Agents; D006020:Glycopeptides; D007769:Lactams; D013256:Steroids