title: The coexistence of thyroid autoimmunity in children and adolescents with various allergic diseases.
abstract: The aim of our study was to investigate the coexistence of thyroid autoimmunity and allergic diseases. The prevalence of thyroid autoantibodies was studied in sera from 140 children with different kinds of allergic diseases, 370 11-13-y-old schoolchildren without allergic diseases serving as controls. The prevalence of thyroid peroxidase autoantibodies was found to be higher among the patients than in the control group, 11.4% vs 5.4% (p < 0.05). Ultrasound investigation identified autoimmune thyroiditis in 4.3% (6/140) of the series, which was later confirmed with fine needle aspiration in all six cases, four of which were unknown prior to the study. Our findings may be useful to alert clinicians that thyroid diseases may be superimposed on allergic children.
authors.affiliation: Department of Paediatrics, Malmö University Hospital, University of Lund, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Lindberg
authors.forename: U B
authors.initials: UB
authors.lastname: Ericsson
authors.forename: B
authors.initials: B
authors.lastname: Fredriksson
authors.forename: P
authors.initials: P
authors.lastname: Nilsson
authors.forename: C M
authors.initials: CM
authors.lastname: Olsson
authors.forename: E
authors.initials: E
authors.lastname: Svenonius
authors.forename: S A
authors.initials: SA
authors.lastname: Ivarsson
mesh_terms: D000293:Adolescent; D001323:Autoantibodies / Q000032:analysis; D001327:Autoimmune Diseases / Q000150:complications* / Q000453:epidemiology / Q000276:immunology; D002648:Child; D015897:Comorbidity; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000150:complications* / Q000453:epidemiology / Q000276:immunology; D007453:Iodide Peroxidase / Q000276:immunology; D008297:Male; D018709:Statistics, Nonparametric; D013954:Thyroglobulin / Q000276:immunology; D013959:Thyroid Diseases / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000276:immunology; D013967:Thyroiditis, Autoimmune / Q000150:complications / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000276:immunology; D014463:Ultrasonography
chemical_list: D001323:Autoantibodies; D013954:Thyroglobulin; D007453:Iodide Peroxidase