Efficacy of low-dose combination of bisoprolol/hydrochlorothiazide compared with amlodipine and enalapril in men and women with essential hypertension.
The efficacy of the low-dose combination of bisoprolol/hydrochlorothiazide was compared with amlodipine and enalapril. The low-dose combination was found to be at least as effective as amlodipine and more effective than enalapril in both men and women.
Papademetriou
V
V
Hypertension Research Clinic, Veterans Affairs Medical Center and Georgetown University, Washington, DC 20422, USA.
Prisant
L M
LM
Neutel
J M
JM
Weir
M R
MR
D000328:Adult; D000368:Aged; D017311:Amlodipine / Q000008:administration & dosage* / Q000009:adverse effects; D000959:Antihypertensive Agents / Q000008:administration & dosage* / Q000009:adverse effects; D017298:Bisoprolol / Q000008:administration & dosage* / Q000009:adverse effects; D001794:Blood Pressure / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D004656:Enalapril / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D006801:Humans; D006852:Hydrochlorothiazide / Q000008:administration & dosage* / Q000009:adverse effects; D006973:Hypertension / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged
D000959:Antihypertensive Agents; D006852:Hydrochlorothiazide; D017311:Amlodipine; D004656:Enalapril; D017298:Bisoprolol