title: [An experimental and clinical study of Ossocol, a compound of hydroxylapatite and collagen].
abstract: Experiments on white rats revealed that introduction of Ossocol, a sponge with a composition of hydroxyl apatite with collagen, into a removed tooth well prevented mandibular atrophy and was conducive to a more smooth defect filling with better compact bone tissue. Ossocol use in 214 patients with bone tissue defects developing after tooth removal, of odontogenic cysts, sequestra, and after radical surgery for periodontal diseases demonstrated a positive effect of this agent on the course of the postoperative period: the defect was more rapidly replaced by bone tissue. No unfavorable local or general reactions to Ossocol implantation were observed.
authors.forename: M M
authors.initials: MM
authors.lastname: Solov'ev
authors.forename: T M
authors.initials: TM
authors.lastname: Alekhova
authors.forename: L G
authors.initials: LG
authors.lastname: Vladimirova
authors.forename: G M
authors.initials: GM
authors.lastname: Mel'tsova
authors.forename: I A
authors.initials: IA
authors.lastname: Ganiev
authors.forename: T D
authors.initials: TD
authors.lastname: Fedosenko
authors.forename: O E
authors.initials: OE
authors.lastname: Khorovskiĭ
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D001861:Bone Regeneration / Q000187:drug effects; D018786:Bone Substitutes / Q000494:pharmacology / Q000627:therapeutic use*; D003094:Collagen / Q000494:pharmacology / Q000627:therapeutic use*; D000075202:Contraindications; D004338:Drug Combinations; D004341:Drug Evaluation; D004353:Drug Evaluation, Preclinical; D017886:Durapatite / Q000494:pharmacology / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008297:Male; D008334:Mandible / Q000473:pathology / Q000601:surgery; D008875:Middle Aged; D051381:Rats; D017208:Rats, Wistar; D013997:Time Factors; D014081:Tooth Extraction / Q000379:methods
chemical_list: D018786:Bone Substitutes; D004338:Drug Combinations; D003094:Collagen; D017886:Durapatite
vernacular_title: Izuchenie v éksperimente i klinike kompozitsii gidroksilapatita c kollagenom--"Ossokola".