title: [Cloning and structure-function analysis of the human S26 ribosomal protein gene].
abstract: Gene HRPS26 encoding the S26 human ribosomal protein has been sequenced. Gene HRPS26 consists of four exons and three introns. Its size is 2027 bp; the size of its mRNA is 438 nucleotides. As most of the genes of ribosomal proteins of vertebrates, the HRPS26 gene has a short first exon, which corresponds to the 5'-untranslated region of mRNA; the origin of transcription is located in the polypyrimidine tract. The functional activity of the cloned HRPS26 promoter region has been confirmed by transcription of hybrid plasmids in HeLa cells.
authors.affiliation: Novosibirsk Institute of Bioorganic Chemistry, Russian Academy of Sciences, Russia.
authors.forename: M L
authors.initials: ML
authors.lastname: Filipenko
authors.forename: N A
authors.initials: NA
authors.lastname: Vinichenko
authors.forename: G G
authors.initials: GG
authors.lastname: Karpova
authors.forename: N P
authors.initials: NP
authors.lastname: Mertvetsov
authors.forename: F
authors.initials: F
authors.lastname: Amaldi
mesh_terms: D001483:Base Sequence; D015500:Chloramphenicol O-Acetyltransferase / Q000235:genetics; D003001:Cloning, Molecular; D004247:DNA; D006367:HeLa Cells; D006801:Humans; D008969:Molecular Sequence Data; D010957:Plasmids; D016133:Polymerase Chain Reaction; D011401:Promoter Regions, Genetic; D012269:Ribosomal Proteins / Q000235:genetics*; D014158:Transcription, Genetic
chemical_list: C489203:RPS26 protein, human; D012269:Ribosomal Proteins; D004247:DNA; D015500:Chloramphenicol O-Acetyltransferase
vernacular_title: Klonirovanie i strukturno-funktsional'nyĭ analiz gena ribosomnogo belka S26 cheloveka.