title: MR of leptomeningeal spinal and posterior fossa amyloid.
abstract: We report an unusual cause of leptomeningeal MR enhancement, amyloid, along the surfaces of the spinal cord and brain stem and in the spinal subarachnoid space, with sacral intradural and epidural deposition. Type I familial amyloid polyneuropathy may cause amyloid deposition along the leptomeninges of the spinal cord and brain in addition to the visceral organs and the peripheral somatic and autonomic nerves.
authors.affiliation: Department of Radiology, Loyola University Medical Center, Maywood, Ill 60153, USA.
authors.forename: S
authors.initials: S
authors.lastname: Horowitz
authors.forename: C
authors.initials: C
authors.lastname: Thomas
authors.forename: G
authors.initials: G
authors.lastname: Gruener
authors.forename: S
authors.initials: S
authors.lastname: Nand
authors.forename: J F
authors.initials: JF
authors.lastname: Shea
mesh_terms: D000328:Adult; D000682:Amyloid / Q000378:metabolism*; D017772:Amyloid Neuropathies / Q000175:diagnosis / Q000378:metabolism* / Q000473:pathology; D001099:Arachnoid / Q000378:metabolism* / Q000473:pathology; D001933:Brain Stem / Q000378:metabolism* / Q000473:pathology; D003388:Cranial Fossa, Posterior; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010841:Pia Mater / Q000378:metabolism* / Q000473:pathology
chemical_list: D000682:Amyloid