title: Acute vision loss resulting from complications of ethanol abuse.
abstract: BACKGROUND
  Alcoholism affects about 10% of men and 3% to 5% of women in their lifetime. It is a primary chronic disease with genetic, psychosocial, and environmental factors that influence its development and manifestations.
  
  
  METHODS
  A 47-year-old alcoholic male manifested mild nutritional optic atrophy, chronic anemia, pancreatitis, and previous gastrojejunostomy and pancreaticojejunostomy. After an acute episode of hypovolemic blood loss from peptic ulceration, there was increased bi-temporal optic nerve head pallor with permanent vision loss, central scotoma, and an acquired red-green color vision defect.
  
  
  RESULTS
  The genetic, psychosocial, and systemic effects of ethanol abuse--including anemia, cardiomyopathy, gastric/duodenal ulceration, pancreatitis, and neurologic deficits--are reviewed. Appropriate treatment and management of ocular manifestations and complications from alcoholism are discussed. Prophylactic topical therapy may be indicated to restore the balance between intraocular tension and optic nerve head perfusion in an attempt to prevent further axonal loss.
  
  
  CONCLUSIONS
  Alcohol-induced nutritional optic neuropathy should not be viewed as an isolated ocular entity, but rather as a potentially treatable neurologic problem. An interdisciplinary approach is essential optimal in the management of the alcoholic patient.
authors.affiliation: Alpine Vision, Orem, Utah, USA.
authors.forename: M
authors.initials: M
authors.lastname: Shimozono
authors.forename: J C
authors.initials: JC
authors.lastname: Townsend
authors.forename: P F
authors.initials: PF
authors.lastname: Ilsen
authors.forename: D C
authors.initials: DC
authors.lastname: Bright
mesh_terms: D000208:Acute Disease; D000437:Alcoholism / Q000150:complications*; D003117:Color Vision Defects / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009748:Nutrition Disorders / Q000209:etiology; D009901:Optic Nerve Diseases / Q000209:etiology; D010437:Peptic Ulcer / Q000209:etiology; D012607:Scotoma / Q000209:etiology; D014786:Vision Disorders / Q000209:etiology*