[Acquired toxoplasmosis with cerebral involvement and subsequent hearing loss].
In immunocompetent patients the postnatally acquired toxoplasmosis is usually a mild or asymptomatic disease. CNS manifestations are rare, e.g. in patients with HIV infection or in patients with other types of immunosuppression. We report on a 9-year old healthy boy, who was hospitalized after one week with subfebrile temperatures and headache with clinical signs of encephalitis and unilateral deafness. We diagnosed a toxoplasmosis and treated the patient with pyrimethamine and sulfadiazine. While most of the signs and symptoms disappeared rapidly the deafness persisted.
Rösch
D
D
Universitätskinderklinik, Universität Leipzig.
Handrick
W
W
Lietz
R
R
Blatz
R
R
König
E
E
D000890:Anti-Infective Agents / Q000627:therapeutic use; D001309:Auditory Threshold; D002648:Child; D005500:Follow-Up Studies; D006316:Hearing Loss, High-Frequency / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008297:Male; D016781:Toxoplasmosis, Cerebral / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
D000890:Anti-Infective Agents; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
Erworbene Toxoplasmose mit zerebraler Beteiligung und nachfolgender Hörstörung.