title: Non steroidal anti-inflammatory drugs, cyclooxygenase selectivity and gastrointestinal toxicity.
authors.forename: M
authors.initials: M
authors.lastname: Jacob
authors.forename: R
authors.initials: R
authors.lastname: Simpson
authors.forename: I
authors.initials: I
authors.lastname: Bjarnason
mesh_terms: D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D051545:Cyclooxygenase 1; D051546:Cyclooxygenase 2; D004064:Digestive System / Q000098:blood supply / Q000187:drug effects* / Q000201:enzymology; D006801:Humans; D007413:Intestinal Mucosa / Q000098:blood supply / Q000187:drug effects / Q000201:enzymology; D007527:Isoenzymes / Q000096:biosynthesis / Q000187:drug effects*; D008565:Membrane Proteins; D015394:Molecular Structure; D011451:Prostaglandin-Endoperoxide Synthases / Q000096:biosynthesis / Q000187:drug effects*; D012039:Regional Blood Flow / Q000187:drug effects
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007527:Isoenzymes; D008565:Membrane Proteins; D051545:Cyclooxygenase 1; D051546:Cyclooxygenase 2; C496511:PTGS1 protein, human; C496540:PTGS2 protein, human; D011451:Prostaglandin-Endoperoxide Synthases