Terrien's marginal degeneration associated with erythema elevatum diutinum.
OBJECTIVE
To describe a patient with Terrien's marginal degeneration associated with a chronic skin disease, erythema elevatum diutinum.


METHODS
A 27-year-old woman with peripheral thinning of her left cornea associated with adjacent conjunctival and episcleral inflammation was clinically examined.


RESULTS
Episodes of worsening skin lesions were associated with development of inflammation in her left eye. Administration of sulfones was effective for reducing both skin and ocular inflammation.


CONCLUSIONS
Erythema elevatum diutinum should be considered an underlying systemic disease of Terrien's marginal degeneration.
Shimazaki
J
J
Department of Ophthalmology, Tokyo Dental College, Chiba, Japan.
Yang
H Y
HY
Shimmura
S
S
Tsubota
K
K
D000328:Adult; D002908:Chronic Disease; D003078:Colchicine / Q000627:therapeutic use; D003228:Conjunctiva / Q000473:pathology; D003229:Conjunctival Diseases / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D003315:Cornea / Q000473:pathology; D003320:Corneal Ulcer / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D004359:Drug Therapy, Combination; D004890:Erythema / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D005260:Female; D006801:Humans; D017444:Skin Diseases, Papulosquamous / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D012460:Sulfasalazine / Q000627:therapeutic use
D012460:Sulfasalazine; D003078:Colchicine