Ile50Val variant of IL4R alpha upregulates IgE synthesis and associates with atopic asthma.
Mitsuyasu
H
H
Izuhara
K
K
Mao
X Q
XQ
Gao
P S
PS
Arinobu
Y
Y
Enomoto
T
T
Kawai
M
M
Sasaki
S
S
Dake
Y
Y
Hamasaki
N
N
Shirakawa
T
T
Hopkin
J M
JM
D019943:Amino Acid Substitution; D000818:Animals; D001249:Asthma / Q000150:complications / Q000276:immunology*; D006801:Humans; D006967:Hypersensitivity / Q000150:complications / Q000276:immunology; D007073:Immunoglobulin E / Q000096:biosynthesis*; D007532:Isoleucine / Q000235:genetics / Q000276:immunology*; D051379:Mice; D008807:Mice, Inbred BALB C; D019948:Receptors, Interleukin-4 / Q000235:genetics / Q000276:immunology*; D015854:Up-Regulation; D014633:Valine / Q000235:genetics / Q000276:immunology*
D019948:Receptors, Interleukin-4; D007532:Isoleucine; D007073:Immunoglobulin E; D014633:Valine