title: Radiographic and clinical responses to periodontal therapy.
abstract: Mechanical periodontal therapy is widely used for a variety of periodontal conditions. While the clinical efficacy of this treatment has been validated, the radiographic response has not been studied in depth. The purpose of the present study was to examine the clinical and radiographic response to mechanical periodontal therapy, and assess the factors associated with these changes. One hundred and eight patients, with established periodontitis, received oral hygiene instruction and mechanical periodontal therapy for a period of 4 to 5 weeks. Scheduled maintenance visits were performed at 3, 6, 9, and 15 months. Probing depth (PD) and attachment level (AL) measurements were performed at baseline, and at 3 and 15 months. Intraoral radiographs were taken at baseline and 12 to 15 months postsurgery using a Rinn alignment system. Alveolar crestal height (ACH) measurements were performed on a pair of digitized images of the previously taken radiographs. An overall mean of patients' changes for PD, AL, and ACH was initially computed. Active sites (gainers and losers) were determined using a threshold method, and expressed as patient's percentage of active sites (number of active sites of the total sites measured in each patient). Mean overall probing reduction and AL gain was 0.5 mm and 0.44 mm, respectively. Of all sites measured, 16.6% exhibited AL gain, while only 6.2% of all sites exhibited AL loss. Mean overall change in ACH was -0.07 mm, of which 11.8% of all sites exhibited ACH gain, while 15.1% exhibited loss beyond the threshold. Non-smokers presented no change in bone loss, while smokers continued to lose bone at an annual rate of 0.17 mm, despite treatment (P <0.005). Likewise, the average percent of sites per patients showing attachment gain beyond the threshold were much greater in non-smokers (13.9%) compared to 9.0% in smokers (P <0.01). Mean probing reduction was 50% greater among non-smokers (0.6 mm) when compared to smokers (0.4 mm), which was also statistically significant (P <0.05). A positive and significant correlation was established between the percentage of sites with AL gain and sites with ACH gain (Rho =0.40; P=0.0001). It is suggested that monitoring sites for AL and ACH gain expressed as changes beyond a selective threshold is an important outcome variable in treatment studies.
authors.affiliation: Periodontal Disease Research Center, Department of Oral Biology, School of Dental Medicine, State University of New York, Buffalo 14214-3092, USA. Machtei@rambam.health.gov.il
authors.forename: E E
authors.initials: EE
authors.lastname: Machtei
authors.forename: E
authors.initials: E
authors.lastname: Hausmann
authors.forename: M
authors.initials: M
authors.lastname: Schmidt
authors.forename: S G
authors.initials: SG
authors.lastname: Grossi
authors.forename: R
authors.initials: R
authors.lastname: Dunford
authors.forename: R
authors.initials: R
authors.lastname: Schifferle
authors.forename: K
authors.initials: K
authors.lastname: Munoz
authors.forename: G
authors.initials: G
authors.lastname: Davies
authors.forename: J
authors.initials: J
authors.lastname: Chandler
authors.forename: R J
authors.initials: RJ
authors.lastname: Genco
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging*; D000539:Alveolar Process / Q000000981:diagnostic imaging; D001861:Bone Regeneration; D012534:Dental Scaling; D004522:Educational Status; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009811:Odontometry; D017063:Outcome Assessment, Health Care; D017622:Periodontal Attachment Loss / Q000000981:diagnostic imaging* / Q000628:therapy*; D010512:Periodontal Index; D010518:Periodontitis / Q000000981:diagnostic imaging* / Q000628:therapy*; D011859:Radiography; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects; D018709:Statistics, Nonparametric