title: [Current principles and methods of radical therapy for locally extensive esophageal and gastroesophageal cancer].
abstract: The results of radical surgical and combined treatment of 124 cases of esophageal and cardioesphageal tumors are presented. Extensive local disease (stage III, T2-4N0-2M0) was diagnosed in 113 patients (91.1%). Esophagoectomy with transmediastinal esophagogastroplasty and cervical esophagostomy proved most useful for esophageal tumor, while extensive surgery after Lewis in combination with extirpation or proximal resection of the stomach--for proximal gastric disease involving the esophagus. Combined surgery with resection of adjacent organs was carried out in 50%. Post-operative mortality rates were reduced to 7.1% due to application of effective surgical, anesthetic and intensive care procedures. The 3-year survival rate was 26.5%. Prognosis improved significantly when radiation was used prior to dissection of lymph nodes.
authors.affiliation: Prof. N.N. Petrov Research Institute of Oncology, Ministry of Health of the RF, St. Petersburg.
authors.forename: N N
authors.initials: NN
authors.lastname: Simonov
authors.forename: A V
authors.initials: AV
authors.lastname: Guliaev
authors.forename: O R
authors.initials: OR
authors.lastname: Mel'nikov
authors.forename: T K
authors.initials: TK
authors.lastname: Makeeva
authors.forename: S V
authors.initials: SV
authors.lastname: Kanaev
authors.forename: A V
authors.initials: AV
authors.lastname: Shulenov
authors.forename: M M
authors.initials: MM
authors.lastname: Konstantinova
authors.forename: A I
authors.initials: AI
authors.lastname: Evtiukhin
authors.forename: I V
authors.initials: IV
authors.lastname: Dunaevskiĭ
authors.forename: V M
authors.initials: VM
authors.lastname: Gel'fond
mesh_terms: D002299:Cardia; D013505:Digestive System Surgical Procedures / Q000379:methods* / Q000401:mortality; D004938:Esophageal Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D016629:Esophagectomy; D004944:Esophagoplasty; D004946:Esophagostomy; D005260:Female; D005743:Gastrectomy; D015391:Gastroplasty; D005774:Gastrostomy; D006801:Humans; D008197:Lymph Node Excision; D008297:Male; D009367:Neoplasm Staging; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery*; D016019:Survival Analysis; D016896:Treatment Outcome
vernacular_title: Sovremennye printsipy i metody radikal'nogo lecheniia mectorasprostranennogo raka pishchevoda i kardioèzofageal'noĭ zony.