title: Neonatal management. Role for early intervention.
abstract: Although performing pyeloplasty on an infant with a relatively healthy kidney prior to the onset of renal damage is not as well-accepted as "aggressive observation," the authors argue that early intervention is the more "conservative" or safe method of treatment for infants with ureteropelvic junction (UPJ) obstruction. Using experimental and clinical data, the authors demonstrate that prolonged partial UPJ obstruction in the developing kidney causes significant renal morbidity with time.
authors.affiliation: Department of Urology, University of California, San Francisco, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: DiSandro
authors.forename: B A
authors.initials: BA
authors.lastname: Kogan
mesh_terms: D000818:Animals; D006168:Guinea Pigs; D006801:Humans; D006869:Hydronephrosis / Q000151:congenital / Q000175:diagnosis / Q000517:prevention & control*; D007231:Infant, Newborn; D051381:Rats; D014517:Ureteral Obstruction / Q000150:complications / Q000175:diagnosis / Q000601:surgery