Autosomal dominant juvenile recurrent parotitis.
Juvenile recurrent parotitis is a common cause of inflammatory salivary gland swelling in children. A variety of aetiological factors has been proposed for the condition. Here we present a family where four members had juvenile recurrent parotitis and where two other family members may have had an atypical form of the condition. The segregation pattern in the family is consistent with autosomal dominant inheritance with incomplete penetrance and this suggests that, at least in some cases, genetic factors may be implicated in juvenile recurrent parotitis.
Reid
E
E
Department of Medical Genetics, University of Cambridge, Addenbrooke's NHS Trust, UK.
Douglas
F
F
Crow
Y
Y
Hollman
A
A
Gibson
J
J
D002648:Child; D002675:Child, Preschool; D005260:Female; D005799:Genes, Dominant; D006801:Humans; D008297:Male; D010309:Parotitis / Q000235:genetics*; D010375:Pedigree; D012008:Recurrence