A new variant chromosomal translocation t(2;2)(p23;q23) in CD30+/Ki-1+ anaplastic large cell lymphoma.
A case with a complex chromosome abnormality with a t(2;2)(p23;q23) in CD30+/Ki-1+ anaplastic large cell lymphoma (ALCL) is described. This chromosome aberration has not been reported previously in neoplastic diseases and was associated with T-cell phenotype and involvement of the nasopharynx by the tumour.
Mitev
L
L
Department of Cytogenetics, Military Medical Academy, Faculty of Medicine, National Centre of Oncology, Sofia, Bulgaria.
Christova
S
S
Hadjiev
E
E
Guenova
M
M
Oucheva
R
R
Valkov
I
I
Manolova
Y
Y
D000368:Aged; D002889:Chromosomes, Human, Pair 2; D006801:Humans; D007621:Karyotyping; D017728:Lymphoma, Large-Cell, Anaplastic / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic