title: Aural symptoms and hearing loss in patients with lupus.
abstract: OBJECTIVE
  Systemic lupus erythematosus causes widespread tissue injury from deposition of immune complexes. The prevalence of aural symptoms in this disease was evaluated.
  
  
  METHODS
  The presence of tinnitus, hearing loss, and fluctuating hearing was evaluated by a self-directed questionnaire in patients aged 65 or less from a lupus clinic. Patients reporting aural symptoms were compared with those reporting none, by use of demographics and disease duration. Comparison was also made with historic serologic data. Audiometry was offered to all patients with lupus reporting aural symptoms and was completed in 10.
  
  
  RESULTS
  Twenty-six (31%) of 84 patients with lupus reported aural symptoms. Patients reported a combination of symptoms: unilateral hearing loss with or without tinnitus in 13 (15%) of 84 and bilateral hearing loss with or without tinnitus in 14 (17%) of 84. No statistical difference was measured between symptomatic and asymptomatic patients when compared by average age, duration of disease, history of noise exposure, head trauma, and infectious ear diseases. Statistically significant differences were detected only when comparing average creatinine and C3 levels. Of those patients tested by audiometry, 7 of 10 had abnormal pure-tone thresholds. Asymmetric findings were present in 6 of these 7 patients tested.
  
  
  CONCLUSIONS
  Aural symptoms are prevalent among patients with lupus. Asymmetric symptoms and hearing loss are most common. The cause may relate to immune-complex disease and/or vasculitis.
authors.affiliation: Department of Otolaryngology, SUNY-Health Science Center at Brooklyn, New York 11203, USA.
authors.forename: N M
authors.initials: NM
authors.lastname: Sperling
authors.forename: K
authors.initials: K
authors.lastname: Tehrani
authors.forename: A
authors.initials: A
authors.lastname: Liebling
authors.forename: E
authors.initials: E
authors.lastname: Ginzler
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D034381:Hearing Loss / Q000209:etiology*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008875:Middle Aged; D014012:Tinnitus / Q000209:etiology*