title: Granuloma faciale: an ultrastructural study.
abstract: Granuloma faciale is an uncommon process that can easily be confused with other skin diseases. To avoid incorrect treatment, correct diagnosis is of primary importance. A diagnosis of granuloma faciale can be made by a microscopic study of the dense granulomatous infiltrate in the reticular dermis with abundant polynuclear eosinophils and by an ultrastructural study of the eosinophils, which show characteristic alterations in their cytoplasmatic granules. The absence of Langerhans granules differentiates granuloma faciale from histiocytosis X.
authors.affiliation: Department of Pathology, Faculty of Medicine, University of Murcia, Spain.
authors.forename: V
authors.initials: V
authors.lastname: Vicente Ortega
authors.forename: P
authors.initials: P
authors.lastname: Sánchez-Pedreño
authors.forename: J
authors.initials: J
authors.lastname: Rodríguez Vicente
mesh_terms: D001706:Biopsy; D004804:Eosinophils / Q000648:ultrastructure*; D005148:Facial Dermatoses / Q000276:immunology / Q000473:pathology*; D005260:Female; D019085:Fluorescent Antibody Technique, Direct; D006099:Granuloma / Q000276:immunology / Q000473:pathology*; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D008854:Microscopy, Electron; D008875:Middle Aged; D012867:Skin / Q000276:immunology / Q000473:pathology / Q000648:ultrastructure
chemical_list: D007136:Immunoglobulins