title: A single amino acid change in turnip crinkle virus movement protein p8 affects RNA binding and virulence on Arabidopsis thaliana.
abstract: Comparison of the symptoms caused by turnip crinkle virus strain M (TCV-M) and TCV-B infection of a resistant Arabidopsis thaliana line termed Di-17 demonstrates that TCV-B has a greater ability to spread in planta. This ability is due to a single amino acid change in the viral movement protein p8 and inversely correlates with p8 RNA binding affinity.
authors.affiliation: Waksman Institute and Department of Molecular Biology and Biochemistry, Rutgers, the State University of New Jersey, Piscataway, New Jersey 08854-8020, USA.
authors.forename: K K
authors.initials: KK
authors.lastname: Wobbe
authors.forename: M
authors.initials: M
authors.lastname: Akgoz
authors.forename: D A
authors.initials: DA
authors.lastname: Dempsey
authors.forename: D F
authors.initials: DF
authors.lastname: Klessig
mesh_terms: D017360:Arabidopsis / Q000821:virology*; D019184:Carmovirus / Q000235:genetics / Q000472:pathogenicity*; D053830:Plant Viral Movement Proteins; D012367:RNA, Viral / Q000378:metabolism*; D013329:Structure-Activity Relationship; D014764:Viral Proteins / Q000737:chemistry / Q000502:physiology*; D014774:Virulence
chemical_list: D053830:Plant Viral Movement Proteins; D012367:RNA, Viral; D014764:Viral Proteins