[Mitochondrial respiration and oxidative phosphorylation in the kidneys of white rats under conditions of hemic hypoxia and the use of different suture materials].
The activity of processes of mitochondrial respiration and oxidative phosphorylation has been studied in the experiment with white rats, which had been carried out nephrotomy with following use for suture such absorbable surgical threads as catgut plain biofil (of dura mater spinalis of the cattle) and biofil modified with succinate. The research proves the use of catgut plain decreases of biosynthetic processes and effectiveness of oxidative phosphorylation in 7 and 14 days of postoperative period shown more distinctively in condition of blood loss. The use of biofil modified with succinate results in the significant increase of oxidative phosphorylation in the sutured renal tissue. Following thing can be interred the investigation of influence of absorbable suture materials in metabolic processes in sutured tissues in condition of modelling of pathological processes, in particular of hypoxia, reflects the biological qualities of studied threads more distinctively, kidneys.
Kostenko
V O
VO
Medical Stomatological Academy, Ministry of Public Health of the Ukraine, Poltava.
D000818:Animals; D005260:Female; D000860:Hypoxia / Q000378:metabolism*; D007668:Kidney / Q000187:drug effects / Q000378:metabolism* / Q000601:surgery; D008297:Male; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism*; D010084:Oxidation-Reduction / Q000187:drug effects; D010085:Oxidative Phosphorylation / Q000187:drug effects; D011184:Postoperative Period; D051381:Rats; D017208:Rats, Wistar; D019802:Succinic Acid / Q000494:pharmacology; D013537:Sutures / Q000009:adverse effects*; D013997:Time Factors
D019802:Succinic Acid
Stan mitokhondrial'noho dykhannia ta okysliuval'noho fosforyliuvannia u nyrkakh bilykh shchuriv za umov hemichnoï hipoksi ta pry zastosuvanni riznoho shovnoho materialu.