title: Electrodermal activity and obstetric complications in schizophrenia.
abstract: The pregnancy and birth records of 79 schizophrenic patients, from whom adult electrodermal data were available, were systematically evaluated for obstetric complications using 34 criteria of nonoptimality in pregnancy, delivery, and postpartum periods. Patients with many obstetric complications had lower levels of electrodermal activity. For frequency of skin conductance responses and spontaneous fluctuations in skin conductance, the association was more evident for women than for men. However, the ratio of stimulus-elicited to spontaneous skin conductance responses showed a reliable association with obstetric complications without any gender differences. The relationship between obstetric complications and electrodermal activity was interpreted in terms of neurodevelopmental insults resulting in structural brain abnormalities interfering with orienting and electrodermal activity.
authors.affiliation: Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden. arneo@psyk.ks.se
authors.forename: A
authors.initials: A
authors.lastname: Ohman
authors.forename: C M
authors.initials: CM
authors.lastname: Hultman
mesh_terms: D000293:Adolescent; D000328:Adult; D001143:Arousal / Q000502:physiology*; D001921:Brain / Q000503:physiopathology; D005260:Female; D005712:Galvanic Skin Response / Q000502:physiology*; D006801:Humans; D007231:Infant, Newborn; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D019965:Neurocognitive Disorders / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology; D007744:Obstetric Labor Complications / Q000503:physiopathology*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D011446:Prospective Studies; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis / Q000503:physiopathology*; D012565:Schizophrenic Psychology