title: [Hypoxic-ischemic encephalopathy in newborn infants. Acute period and outcome].
abstract: Ninety four neonates with hypoxic ischemic encephalopathy HIE attended at the University of Ribeirão Preto since 1982 were studied in terms of the neurological alterations during the acute phase and outcome over a mean period of 47 months. From 43 newborns with HIE I, 40 recovered within 96 hours and 3 died. Among 40 infants with HIE II, 37.5% recovered within the first week, and the others continued abnormal beyond the 7th day. All 11 infants with HIE III died before the second month of life. The HIE I group had no motor sequelae. Among the HIE II group, 34.5% showed cerebral palsy and 17.7% neuromotor retardation. 80.0% of those with sequelae persisted abnormal beyond 7th day of life, during the acute phase of the HIE. Epilepsy occurred in 17.5% of cases with HIE grade II, only among those with neuromotor sequelae. The IQ test did not show statistically significant difference between the HIE I, II without motor sequelae and the control groups. The authors reaffirm the value of the findings in the acute phase of HIE on the outcome of these patients.
authors.affiliation: Departamento de Neurologia, Psiquiatria e Psicologia Médica, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo (FMRP/USP), Brasil.
authors.forename: C A
authors.initials: CA
authors.lastname: Funayama
authors.forename: M V
authors.initials: MV
authors.lastname: de Moura-Ribeiro
authors.forename: A L
authors.initials: AL
authors.lastname: Gonçalves
mesh_terms: D000208:Acute Disease; D001034:Apgar Score; D001238:Asphyxia Neonatorum / Q000175:diagnosis*; D002545:Brain Ischemia / Q000150:complications / Q000175:diagnosis*; D002547:Cerebral Palsy / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D005311:Fetal Hypoxia / Q000175:diagnosis*; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D012307:Risk Factors
vernacular_title: Encefalopatia hipóxico-isquêmica em recém-nascidos a termo. Aspectos da fase aguda e evolução.