title: Herd size and sero-prevalence of Salmonella enterica in Danish swine herds: a random-effects model for register data.
abstract: The association between herd size and sero-prevalence of Salmonella was assessed in a random-effects model with herd size, county and date of slaughter as fixed effects. A total of 510,915 meat-juice samples from 14,593 herds located in 13 counties in Denmark was included in the study. A random-effects model was developed from separate models for smaller strata of data from herds with approximately equal sizes. The combined model was analysed and the results reported. Herd size was positively associated with the sero-prevalence of Salmonella enterica, but the size of the association was biologically of little importance, because the within-herd and the between-herd variations were relatively large in comparison. The relative magnitudes of the variance components indicated that factors associated with both the herd level and the pig level could be important in the prediction of seroprevalence of S. enterica.
authors.affiliation: Danish Veterinary Laboratory, Copenhagen, Denmark. bxc@svs.dk
authors.forename: B
authors.initials: B
authors.lastname: Carstensen
authors.forename: J
authors.initials: J
authors.lastname: Christensen
mesh_terms: D000704:Analysis of Variance; D000822:Animal Husbandry / Q000379:methods; D000818:Animals; D000907:Antibodies, Bacterial / Q000032:analysis*; D003430:Cross-Sectional Studies; D003627:Data Interpretation, Statistical; D003718:Denmark / Q000453:epidemiology; D008460:Meat / Q000382:microbiology; D015233:Models, Statistical; D011159:Population Surveillance; D012042:Registries; D012481:Salmonella Infections, Animal / Q000453:epidemiology*; D019779:Salmonella enterica / Q000276:immunology; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology*
chemical_list: D000907:Antibodies, Bacterial