[Technique for protecting the liver graft less tolerant than the small bowel to heat-induced ischemia in experimental liver + small bowel transplantation in swine].
Multivisceral and orthotopic liver/small bowel transplantations have been performed to treat patients with intestinal failure associated with liver failure induced by parenteral nutrition. The aim of this experimental study was to determine the experimental liver-small bowel harvesting and transplantation technique that achieves the best compromise between liver and intestine ischemia times in pigs. Initial portal revascularization of the liver which reduces the hepatic warm ischemia time after cold ischemia preparation of the graft immersed in lactated ringer's solution at 4 degrees C, reduce the risk of primary non function of the graft.
Richer
J P
JP
Faculté de Médecine de Poitiers, Service de Chirurgie Viscérale, Hôpital J.-Bernard.
Faure
J P
JP
Dugue
T
T
Journe
F
F
Bon
D
D
Maillot
N
N
Mothes
D
D
Barbier
J
J
Carretier
M
M
D000818:Animals; D007108:Immune Tolerance; D007421:Intestine, Small / Q000637:transplantation*; D016031:Liver Transplantation; D012106:Research; D013552:Swine
Technique visant à protéger le greffon hépatique moins tolérant à l'ischémie chaude que le grêle dans une transplantation expérimentale foie + grêle chez le porc.