Postmortem diagnosis of accidental cocaine intoxication in a dog.
Despite an abundance of data on the experimental effects of cocaine in dogs, no detailed reports documenting accidental cocaine exposure in domestic pets have been reported in the veterinary literature. A case of cocaine intoxication is described in a 19-mo-old male catahoula hound in which the diagnosis was confirmed using histopathology, thin-layer chromatography and mass spectrometry. The case was presented as a possible intoxication of unknown etiology. Routine toxicologic screens and characteristic histologic lesions provided evidence for the diagnosis without prior suspicion of cocaine involvement.
Frazier
K
K
Veterinary Diagnostic and Investigational Laboratory, College of Veterinary Medicine, University of Georgia, Tifton 31793, USA.
Colvin
B
B
Hullinger
G
G
D000059:Accidents; D000818:Animals; D003042:Cocaine / Q000506:poisoning*; D004283:Dog Diseases / Q000139:chemically induced* / Q000175:diagnosis*; D004285:Dogs; D017809:Fatal Outcome; D006321:Heart / Q000187:drug effects; D008297:Male; D009206:Myocardium / Q000473:pathology; D011654:Pulmonary Edema / Q000473:pathology / Q000662:veterinary*; D012640:Seizures / Q000473:pathology / Q000662:veterinary*; D013270:Stomach / Q000187:drug effects / Q000473:pathology; D014661:Vasoconstriction / Q000187:drug effects; D014662:Vasoconstrictor Agents / Q000506:poisoning*
D014662:Vasoconstrictor Agents; D003042:Cocaine