title: [Spontaneous subdural hematoma in a 18-day-old male newborn infant with severe hemophilia A].
abstract: Most intracranial bleedings in hemophiliacs occur in patients more than 6 months of age. In the neonatal period, this complication is rare and almost always observed in the first week of life. Based on a review of the literature, intracranial hemorrhage is an exceedingly rare occurrence in infants with hemophilia aged 2 weeks-6 months. We report on a male infant with hemophilia A who was referred to our hospital on day 18 because of pallor and jaundice. The neurological examination was normal. A cerebral ultrasound showed a left sided subdural hematoma with a shift of the midline structures to the right. Packed red blood cells (10 ml/kg) and factor VIII replacement (250 IU) were rapidly instituted and a craniotomy with evacuation of the hematoma was performed. The postoperative course was uneventful. On discharge, the neurological examination was considered normal.
authors.affiliation: Klinik mit Poliklinik für Kinder und Jugendliche, Universität Erlangen-Nürnberg.
authors.forename: M
authors.initials: M
authors.lastname: Ries
authors.forename: J
authors.initials: J
authors.lastname: Klinge
authors.forename: R
authors.initials: R
authors.lastname: Rauch
authors.forename: C
authors.initials: C
authors.lastname: Chen
authors.forename: K H
authors.initials: KH
authors.lastname: Deeg
mesh_terms: D004453:Echoencephalography; D006408:Hematoma, Subdural / Q000175:diagnosis / Q000235:genetics*; D006467:Hemophilia A / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D009460:Neurologic Examination; D010375:Pedigree; D014057:Tomography, X-Ray Computed
vernacular_title: Spontanes Subduralhämatom bei einem 18 Tage alten männlichen Neugeborenen mit schwerer Hämophilie A.