title: The agnogene of the human polyomavirus BK is expressed.
abstract: Primate polyomavirus genomes all contain an open reading frame at the 5' end of the late coding region called the agnogene. A simian virus 40 agnoprotein with unknown functions has previously been demonstrated. We now show that a BK virus agnoprotein appears in the perinuclear area and cytoplasm late in the infectious cycle. It is phosphorylated in vivo and coimmunoprecipitates with a subset of host cell proteins.
authors.affiliation: Department of Virology, Institute of Medical Biology, University of Tromso, N-9037 Tromso, Norway.
authors.forename: C H
authors.initials: CH
authors.lastname: Rinaldo
authors.forename: T
authors.initials: T
authors.lastname: Traavik
authors.forename: A
authors.initials: A
authors.lastname: Hey
mesh_terms: D001739:BK Virus / Q000737:chemistry* / Q000235:genetics; D006801:Humans; D010766:Phosphorylation; D011233:Precipitin Tests; D014764:Viral Proteins / Q000032:analysis* / Q000235:genetics / Q000378:metabolism; D054334:Viral Regulatory and Accessory Proteins; D000086082:Viroporin Proteins
chemical_list: D014764:Viral Proteins; D054334:Viral Regulatory and Accessory Proteins; C042559:agnoprotein, polyomavirus; D000086082:Viroporin Proteins