title: Flow visualization as a complementary tool to hemolysis testing in the development of centrifugal blood pumps.
abstract: With a 250% scaled-up pump model, high speed video camera, and argon ion laser light sheet, flow patterns related to hemolysis were visualized and analyzed with 4 frame particle tracking software. Different flow patterns and shear distributions were clarified by flow visualization for pumps modified to have different hemolysis levels. A combination of in vitro hemolysis tests, flow visualization, and CFD analysis suggested a close relationship between hemolysis and high shear caused by small impeller/casing gaps. Because arbitrary cross sections can be illuminated by laser light sheet, flow visualization is a useful tool in finding locations related to hemolysis in the design process of rotary blood pumps.
authors.affiliation: Mechanical Engineering Laboratory, Tsukuba, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Yamane
authors.forename: B
authors.initials: B
authors.lastname: Asztalos
authors.forename: M
authors.initials: M
authors.lastname: Nishida
authors.forename: T
authors.initials: T
authors.lastname: Masuzawa
authors.forename: K
authors.initials: K
authors.lastname: Takiura
authors.forename: Y
authors.initials: Y
authors.lastname: Taenaka
authors.forename: Y
authors.initials: Y
authors.lastname: Konishi
authors.forename: Y
authors.initials: Y
authors.lastname: Miyazoe
authors.forename: K
authors.initials: K
authors.lastname: Ito
mesh_terms: D001696:Biomechanical Phenomena; D001783:Blood Flow Velocity / Q000502:physiology; D006353:Heart-Assist Devices / Q000639:trends*; D006461:Hemolysis / Q000502:physiology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D007834:Lasers; D008962:Models, Theoretical