title: The interleukin-17 gene of herpesvirus saimiri.
abstract: In comparison to wild-type herpesvirus saimiri, viral interleukin-17 gene knockout mutants have unaltered behavior regarding viral replication, T-cell transformation in vitro, and pathogenicity in cottontop tamarins. Thus, this gene is not required for T-cell lymphoma induction but may contribute to apathogenic viral persistence in the natural host, the squirrel monkey.
authors.affiliation: Institut für Klinische und Molekulare Virologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, D-91054 Erlangen, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Knappe
authors.forename: C
authors.initials: C
authors.lastname: Hiller
authors.forename: H
authors.initials: H
authors.lastname: Niphuis
authors.forename: F
authors.initials: F
authors.lastname: Fossiez
authors.forename: M
authors.initials: M
authors.lastname: Thurau
authors.forename: S
authors.initials: S
authors.lastname: Wittmann
authors.forename: E M
authors.initials: EM
authors.lastname: Kuhn
authors.forename: S
authors.initials: S
authors.lastname: Lebecque
authors.forename: J
authors.initials: J
authors.lastname: Banchereau
authors.forename: B
authors.initials: B
authors.lastname: Rosenwirth
authors.forename: B
authors.initials: B
authors.lastname: Fleckenstein
authors.forename: J
authors.initials: J
authors.lastname: Heeney
authors.forename: H
authors.initials: H
authors.lastname: Fickenscher
mesh_terms: D000818:Animals; D005814:Genes, Viral; D006567:Herpesvirus 2, Saimiriine / Q000235:genetics*; D020381:Interleukin-17; D007378:Interleukins / Q000235:genetics*; D008213:Lymphocyte Activation; D012452:Saguinus; D013601:T-Lymphocytes / Q000276:immunology; D014779:Virus Replication
chemical_list: D020381:Interleukin-17; D007378:Interleukins