title: Uremic optic neuropathy. A uremic manifestation mandating dialysis.
abstract: A 41-year-old male patient in end-stage renal failure presented on two occasions, over an 18-month period, with painless unilateral visual deterioration and optic disc edema. Clinical findings were compatible with a diagnosis of uremic optic neuropathy. On his initial presentation, the patient refused the onset of dialysis, resulting in a permanent visual deficit of the left eye. On his subsequent admission with a similar clinical picture, this time of the right eye, dialysis combined with corticosteroid therapy was promptly instituted. This led to a rapid improvement of the visual acuity and visual field defects of the right eye concomitant with subsidence of the edema of the optic nerve head.
authors.affiliation: Department of Nephrology, Meir Hospital, Kfar-Saba, Israel.
authors.forename: Z
authors.initials: Z
authors.lastname: Korzets
authors.forename: E
authors.initials: E
authors.lastname: Zeltzer
authors.forename: M
authors.initials: M
authors.lastname: Rathaus
authors.forename: R
authors.initials: R
authors.lastname: Manor
authors.forename: J
authors.initials: J
authors.lastname: Bernheim
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008775:Methylprednisolone / Q000627:therapeutic use; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control; D018917:Optic Neuropathy, Ischemic / Q000175:diagnosis; D010211:Papilledema / Q000209:etiology / Q000517:prevention & control; D011241:Prednisone / Q000627:therapeutic use; D006435:Renal Dialysis; D014511:Uremia / Q000150:complications* / Q000628:therapy
chemical_list: D005938:Glucocorticoids; D011241:Prednisone; D008775:Methylprednisolone