[Study of immune status indices, levels of alpha-1-thymosin and autoantibodies to thymic epithelial cells in persons who worked in the 30-kilometer zone of the Chernobyl AES depending on the radiation dose].
The indices of immune status, concentration of alpha 1-thymosin and level of thymus epithelial cell autoantibodies in human blood of persons, who had worked in 30-km zone Chernobyl NPP were studied. The decrease in mean number of leukocytes, lymphocytes, CD5+, CD4+, CD8+ cells, content of serum alpha 1-thymosin and increased level of autoantibodies were detected in workers, whose dose rates irradiation were greater than 25 cSv. So, the quality differences in the changes of immune system, which were induced by low dose chronic irradiation were obtained.
Titova
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LD
Institute of Immunology, Ministry of Health of Russian Federation, Moscow.
Sharova
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NI
D001323:Autoantibodies / Q000032:analysis*; D003627:Data Interpretation, Statistical; D004848:Epithelium / Q000276:immunology; D005434:Flow Cytometry; D005455:Fluorescent Antibody Technique; D006801:Humans; D007109:Immunity / Q000528:radiation effects*; D007136:Immunoglobulins / Q000032:analysis; D007962:Leukocytes / Q000276:immunology / Q000528:radiation effects; D016131:Lymphocyte Subsets / Q000276:immunology / Q000528:radiation effects; D008214:Lymphocytes / Q000276:immunology / Q000528:radiation effects; D011210:Power Plants; D011829:Radiation Dosage; D018788:Radioactive Hazard Release; D012397:Rosette Formation; D012984:Software; D013947:Thymosin / Q000097:blood*; D013950:Thymus Gland / Q000276:immunology*; D014455:Ukraine
D001323:Autoantibodies; D007136:Immunoglobulins; D013947:Thymosin
Issledovanie pokazateleĭ immunnogo statusa, soderzhaniia al'fa1-timozina i autoantitel k épitelial'nym kletkam timusa u personala 30-kilometrovoĭ zony Chernobyl'skoĭ AES v zavisimosti ot dozovoĭ nagruzki.