[Cost-effectiveness of hip fracture prevention].
We estimated the Cost Per Avoided Hip Fracture (CPAHF, millions Lira) by osteoporosis treatment, on the basis of a review on randomized controlled trials. Prevention with vitamin D3 in institutionalized elderly women is cost-neutral (CPAHF = -4; 95% CI = -9, +5). Prevention with alendronate in non-institutionalized women screened on bone mineral density generates doubts (CPAHF = 275; 95% CI = 146, 19.426). The cost-effectiveness analyses can strengthen or weaken conclusions of the clinical trials and discourage the use of economically unsustainable preventive treatments whose efficacy is unproven.
Visentin
P
P
U.O.A.D.U. Geriatria Azienda Ospedaliera San Giovanni Battista, Torino.
Ciravegna
R
R
Corcelli
F
F
Fabris
F
F
D000368:Aged; D000369:Aged, 80 and over; D003362:Cost-Benefit Analysis; D003365:Costs and Cost Analysis; D005260:Female; D006620:Hip Fractures / Q000191:economics* / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007558:Italy; D010024:Osteoporosis / Q000150:complications / Q000628:therapy
Costo-efficacia della prevenzione delle fratture di femore.