title: Selective use of cutaneous vesicostomy in prenatally detected and clinically presenting uropathies.
abstract: OBJECTIVE
  To determine if the indications for cutaneous vesicostomy have changed with the advent of prenatal diagnosis and to assess if temporary vesicostomy remains an effective measure in preventing urinary infection and stabilising renal function in children with severe uropathy.
  
  
  METHODS
  Retrospective case note review.
  
  
  RESULTS
  Nineteen patients underwent temporary cutaneous vesicostomy over a 12-year period. Of these, 10 had a prenatally detected uropathy. Children with prenatal findings were diverted at a significantly younger age than cases presenting clinically (33 (range 10-240) vs. 182 days (range 28-425), p = 0.02). In addition, there were significantly more boys diverted in the prenatally detected group (p = 0.02). The majority of clinically presenting infants were diverted because of severe or recurrent urosepsis whereas most prenatally detected cases underwent surgery for progressive renal impairment. In both groups vesicostomy was successful in preventing further urosepsis and resulted in improved renal function. Follow-up data, however, revealed 9 (50%) of 18 patients with chronic renal failure. One patient died prior to stoma closure from septicaemia and renal disease.
  
  
  CONCLUSIONS
  The timing and indications for vesicostomy may be changing in the light of prenatal diagnosis. Temporary vesicostomy diversion remains a simple, effective and easily reversible method of preventing urosepsis and stabilising upper tract function. The poor renal outcome on follow-up may reflect the fact vesicostomy is reserved for infants and children with severe disease.
authors.affiliation: Department of Paediatric Urology, St. James's University Hospital, Leeds, UK.
authors.forename: K A
authors.initials: KA
authors.lastname: Hutton
authors.forename: D F
authors.initials: DF
authors.lastname: Thomas
mesh_terms: D003559:Cystostomy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007676:Kidney Failure, Chronic / Q000517:prevention & control; D007677:Kidney Function Tests; D008297:Male; D011247:Pregnancy; D012189:Retrospective Studies; D013997:Time Factors; D016896:Treatment Outcome; D016216:Ultrasonography, Prenatal; D001743:Urinary Bladder / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D001745:Urinary Bladder Diseases / Q000151:congenital / Q000000981:diagnostic imaging / Q000601:surgery*; D014552:Urinary Tract Infections / Q000517:prevention & control