Appearance of primary endometrial and ovarian clear cell adenocarcinoma 17 months postpartum. A case report.
BACKGROUND
Rare cases of endometrial cancer have been reported within two years postpartum. However, clear cell adenocarcinoma of the endometrium does not appear to have been reported before as occurring in the early postpartum period.


METHODS
A 33-year-old-female experienced abnormal uterine bleeding 17 months after the delivery of her second child by cesarean section. Computed tomography indicated the presence of tumors in the uterus and cul-de-sac. Preoperative evaluation of endometrial cytology revealed adenocarcinoma cells. These cells demonstrated a centrally located nucleus and translucent, clear cytoplasm, with the so-called mirror ball pattern of cell clusters. The cytologic diagnosis was clear cell adenocarcinoma. Postoperative histologic evaluation verified the presence of a solid type of clear cell adenocarcinoma. The patient was considered to have simultaneous primary clear cell adenocarcinoma of the endometrium and ovary.


CONCLUSIONS
Preoperative endometrial cytology correctly suggested the histologic type of cancer.
Ohwada
M
M
Department of Obstetrics and Gynecology, Jichi Medical School, Tochigi, Japan.
Suzuki
M
M
Ohno
T
T
Saito
K
K
Sato
I
I
D018262:Adenocarcinoma, Clear Cell / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood; D002585:Cesarean Section; D016889:Endometrial Neoplasms / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008796:Metrorrhagia / Q000209:etiology; D009378:Neoplasms, Multiple Primary / Q000097:blood / Q000175:diagnosis / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D013997:Time Factors; D014592:Uterine Hemorrhage / Q000209:etiology
D014408:Biomarkers, Tumor