title: The occurrence of Iso 24:0 (22-methyltricosanoic acid) fatty acid in sphingomyelin of rat tissues.
abstract: The occurrence of an unusual fatty acid, iso 24:0 (22-methyltricosanoic acid), has been shown to be present in the sphingomyelin from rat liver by gas liquid chromatography-mass spectrometry. The fatty acid is also present in the sphingomyelin of rat tissues tested, except for brain and fetal serum. Supplementation of diets with L-valine elevated the content of iso 24:0 in rat liver, heart, and kidney sphingomyelin. The fatty acid appears to be present in sphingomyelin of the sera of mice, dogs, and cats, but not humans.
authors.affiliation: Department of Human Biology and Nutritional Sciences, University of Guelph, Ontario, Canada. wbettger.ns@aps.uoguelph.ca
authors.forename: W J
authors.initials: WJ
authors.lastname: Bettger
authors.forename: C B
authors.initials: CB
authors.lastname: Blackadar
authors.forename: M L
authors.initials: ML
authors.lastname: McCorquodale
authors.forename: R
authors.initials: R
authors.lastname: Ewing
mesh_terms: D000818:Animals; D002415:Cats; D004285:Dogs; D005227:Fatty Acids / Q000032:analysis*; D008099:Liver / Q000737:chemistry*; D008297:Male; D008322:Mammals / Q000378:metabolism*; D013058:Mass Spectrometry; D051379:Mice; D009928:Organ Specificity / Q000502:physiology; D051381:Rats; D017208:Rats, Wistar / Q000378:metabolism*; D013045:Species Specificity; D013109:Sphingomyelins / Q000737:chemistry*
chemical_list: C113060:22-methyltricosanoic acid; D005227:Fatty Acids; D013109:Sphingomyelins