title: A novel ETA-AAS background reduction method for determination of lead and cadmium in urine.
abstract: Urinary lead and cadmium level were determined in double diluted urine samples using two modifiers: 1% HNO3 (own modification) and 1.6% NH4H2PO4 that is generally used for matrix modification. The background signal is reduced in the samples diluted with 1% HNO3 because of the modifying effect of nitric acid. Lower variation coefficients were obtained in a run of 10 determinations of each of the samples processed by our method which is an advantageous feature compared with the method using 1.6% NH4H2PO4 as a modifier. Recovery is between 95 and 105% for both methods. The analytical performance, flexible pre-instrumental preparation and minimized risk of sample contamination make the use of 1% HNO3 modifier a reliable method in the routine practice of determination of the urinary Pb and Cd level.
authors.affiliation: Department of Clinical Laboratory, Higher Medical Institute, Plovdiv, Bulgaria.
authors.forename: Z
authors.initials: Z
authors.lastname: Tarulov
authors.forename: T
authors.initials: T
authors.lastname: Kotzev
authors.forename: T
authors.initials: T
authors.lastname: Tsvetkova
mesh_terms: D002104:Cadmium / Q000652:urine*; D006801:Humans; D007854:Lead / Q000652:urine*; D013054:Spectrophotometry, Atomic / Q000379:methods*
chemical_list: D002104:Cadmium; D007854:Lead