Delayed hypoglycemia in a child after ingestion of a single glipizide tablet.
This is the first report to describe the delayed onset of hypoglycemia in a child after ingestion of one tablet of glipizide. A 2-year-old boy was observed to ingest 5 mg glipizide and 25 mg hydrochlorothiazide. Activated charcoal was administered within 35 minutes of ingestion. Hypoglycemia (serum glucose 49 mg/dL) developed 11 hours later. Emergency physicians must be aware of the potential for delayed hypoglycemia in children with single-tablet ingestions of glipizide. Prolonged monitoring of glucose levels is warranted.
Szlatenyi
C S
CS
Division of Emergency Medicine, Brown University School of Medicine, Providence, RI, USA.
Capes
K F
KF
Wang
R Y
RY
D000959:Antihypertensive Agents / Q000506:poisoning; D001786:Blood Glucose / Q000187:drug effects; D002606:Charcoal / Q000008:administration & dosage; D002675:Child, Preschool; D005913:Glipizide / Q000506:poisoning*; D005947:Glucose / Q000008:administration & dosage; D006801:Humans; D006852:Hydrochlorothiazide / Q000506:poisoning; D007003:Hypoglycemia / Q000139:chemically induced* / Q000188:drug therapy; D007004:Hypoglycemic Agents / Q000506:poisoning*; D007262:Infusions, Intravenous; D008297:Male; D013997:Time Factors
D000959:Antihypertensive Agents; D001786:Blood Glucose; D007004:Hypoglycemic Agents; D006852:Hydrochlorothiazide; D002606:Charcoal; D005947:Glucose; D005913:Glipizide