title: Rheumatic fever. The relationships between host, microbe, and genetics.
abstract: Acute rheumatic fever is a delayed, nonsuppurative sequela of a pharyngeal infection with the group A streptococcus. The onset of the disease is usually characterized by an acute febrile illness; however, there may be chronic involvement of the heart and/or central nervous system. The article explores the relationship between the initial infection and host-microbial interactions that may be operative in disease pathogenesis.
authors.affiliation: Hospital for Special Surgery, Cornell University Medical College, New York, New York, USA.
authors.forename: A
authors.initials: A
authors.lastname: Gibofsky
authors.forename: S
authors.initials: S
authors.lastname: Kerwar
authors.forename: J B
authors.initials: JB
authors.lastname: Zabriskie
mesh_terms: D000942:Antigens, Bacterial / Q000276:immunology; D006790:Host-Parasite Interactions / Q000276:immunology*; D006801:Humans; D012213:Rheumatic Fever / Q000235:genetics / Q000276:immunology / Q000382:microbiology
chemical_list: D000942:Antigens, Bacterial