title: Heparin cofactor II: a new marker for pre-eclampsia.
abstract: The plasma levels of heparin cofactor II were determined in pregnant women who were either normotensive, or had essential hypertension, gestational hypertension or pre-eclampsia during the third trimester and 72 h after delivery. Heparin cofactor II levels in the pre-eclampsia group were depressed. The clinical relevance of this finding is the potential utility of heparin cofactor II plasma levels in the differential diagnostic between non-proteinuric hypertension and pre-eclampsia.
authors.affiliation: Unitat de Medicina Materno-fetal, Hospital Universitari de Tarragona Joan XXIII, Universitat Rovira i Virgili, Spain. jbellarta@meditex.es
authors.forename: J
authors.initials: J
authors.lastname: Bellart
authors.forename: R
authors.initials: R
authors.lastname: Gilabert
authors.forename: L
authors.initials: L
authors.lastname: Cabero
authors.forename: J
authors.initials: J
authors.lastname: Fontcuberta
authors.forename: J
authors.initials: J
authors.lastname: Monasterio
authors.forename: R M
authors.initials: RM
authors.lastname: Miralles
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D003937:Diagnosis, Differential; D005260:Female; D015844:Heparin Cofactor II / Q000378:metabolism*; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000150:complications; D011225:Pre-Eclampsia / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D011237:Predictive Value of Tests; D011247:Pregnancy
chemical_list: D015415:Biomarkers; D015844:Heparin Cofactor II