T-cell malignant lymphoma with conjunctival involvement.
OBJECTIVE
To report a rare case of T-cell malignant lymphoma involving the conjunctiva.


METHODS
A 63-year-old woman had rapid onset of bilateral perilimbal congestion and chemosis. Perilimbal thickening with corneal infiltration developed 20 days later. Computed tomography incidentally disclosed a right maxillary sinus mass. Biopsy specimens from the maxillary sinus mass and the left limbus were subjected to histopathologic examination and immunohistochemical study.


RESULTS
T-cell malignant lymphoma of diffuse large cell type, stage IV, was diagnosed. The patient was treated with combination chemotherapy plus 13-cis-retinoic acid and remained in remission 1 1/2 years after diagnosis.


CONCLUSIONS
Conjunctival involvement with T-cell lymphoma may present as episcleritis and chemosis.
Hu
F R
FR
Department of Ophthalmology, National Taiwan University Hospital, Taipei. fungrong@ha.mc.ntu.edu.tw
Lin
J C
JC
Chiang
I P
IP
Yeh
K H
KH
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003230:Conjunctival Neoplasms / Q000737:chemistry / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D016130:Immunophenotyping; D015474:Isotretinoin / Q000627:therapeutic use; D017493:Leukocyte Common Antigens / Q000032:analysis; D016403:Lymphoma, Large B-Cell, Diffuse / Q000737:chemistry / Q000188:drug therapy / Q000473:pathology*; D016399:Lymphoma, T-Cell / Q000737:chemistry / Q000188:drug therapy / Q000473:pathology*; D008444:Maxillary Sinus Neoplasms / Q000737:chemistry / Q000188:drug therapy / Q000473:pathology*; D008875:Middle Aged; D009367:Neoplasm Staging; D014057:Tomography, X-Ray Computed
D017493:Leukocyte Common Antigens; D015474:Isotretinoin