Transient neurotoxicity associated with FK506: MR findings.
We report a patient presenting with transient neurotoxicity who developed edema in the cerebral and cerebellar cortex following bone marrow transplant and administration of FK506, a widely used immunosuppresive agent.
Tomura
N
N
Department of Radiology, Akita UNiversity School of Medicine, Japan.
Kurosawa
R
R
Kato
K
K
Takahashi
S
S
Watarai
J
J
Takeda
O
O
Watanabe
A
A
Takada
G
G
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001929:Brain Edema / Q000139:chemically induced* / Q000175:diagnosis; D002526:Cerebellar Diseases / Q000139:chemically induced* / Q000175:diagnosis; D002540:Cerebral Cortex / Q000187:drug effects* / Q000473:pathology; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006086:Graft vs Host Disease / Q000517:prevention & control; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008279:Magnetic Resonance Imaging; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000628:therapy; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000628:therapy; D012640:Seizures / Q000139:chemically induced; D016559:Tacrolimus / Q000009:adverse effects*
D007166:Immunosuppressive Agents; D016559:Tacrolimus