title: Economising vein-graft surveillance programs.
abstract: OBJECTIVE
  To investigate the effectiveness of two alternative vein-graft surveillance strategies. In the first strategy surveillance was restricted to patients with a possible higher risk of significant stenosis development, i.e., those with a moderate stenosis identified early after the operation. In the second strategy the effects of reducing the number of duplex tests per patient was examined.
  
  
  METHODS
  In a prospective study in three vascular surgical departments 300 patients (300 femoropopliteal or distal grafts) underwent duplex surveillance during the first year after the operation. The duplex-derived PSV-ratio was considered to represent the degree of stenosis. Arteriographic confirmation of suspected stenoses was routinely obtained, and patients without a suspected graft stenosis underwent a consented arteriogram during the first postoperative year. The decision to perform a graft revision was taken on the basis of an arteriographic stenosis of at least 70% diameter reduction. In the first strategy graft categories were defined on the basis of the first postoperative duplex examination: grafts with a PSV-ratio < 1.5, grafts with a PSV-ratio < 1.5-2.0, grafts with a PSV-ratio of 2.0-2.5, grafts with PSV-ratios 2.5-3.0, and grafts with PSV-ratios > 3.0. The primary patency rate at 12 months was compared for these categories. In the second alternative strategy the number of examinations and the percentage of event causing de novo stenoses were analysed per surveillance interval.
  
  
  RESULTS
  The presence of moderate abnormalities at the initial duplex scan did not identify patients with a high risk of an event, as initial PSV-ratios of 1.5-2.0 and 2.0-2.5 (early mild-moderate lesions) had comparable 12-month primary patencies to patients with a PSV-ratio < 1.5 (completely normal grafts): (63%, 73%, and 71%, respectively). The interval incidence of event causing de novo stenoses was 8% of the total number of duplex tests performed at 3 months, and 8% at 6 months after the operation. In patients who had no previous intervention for stenosis and had a normal bypass during the first 6 months postoperatively, a sharp drop in this incidence was seen at 9 and 12 months, with event causing de novo stenoses observed in only 2% and 1% of all duplex tests.
  
  
  CONCLUSIONS
  All patients should be included in a surveillance program, as the presence of a normal vein graft at the first duplex examination does not rule out the subsequent development of graft stenosis. The duration of the surveillance period may be restricted to the first 6 months after operation in patients who have a normal bypass during that time period, as only few stenoses will be missed by this policy.
authors.affiliation: Department of Surgery, Catharina Hospital Eindhoven, The Netherlands.
authors.forename: M M
authors.initials: MM
authors.lastname: Idu
authors.forename: J
authors.initials: J
authors.lastname: Buth
authors.forename: P
authors.initials: P
authors.lastname: Cuypers
authors.forename: W C
authors.initials: WC
authors.lastname: Hop
authors.forename: E D
authors.initials: ED
authors.lastname: van de Pavoordt
authors.forename: J M
authors.initials: JM
authors.lastname: Tordoir
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000792:Angiography; D003251:Constriction, Pathologic / Q000000981:diagnostic imaging / Q000209:etiology; D003363:Cost Control; D005260:Female; D005263:Femoral Artery / Q000601:surgery; D005500:Follow-Up Studies; D006083:Graft Occlusion, Vascular / Q000000981:diagnostic imaging* / Q000209:etiology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery / Q000601:surgery; D011159:Population Surveillance; D011446:Prospective Studies; D012086:Reoperation; D012307:Risk Factors; D018608:Ultrasonography, Doppler / Q000191:economics*; D014654:Vascular Patency; D014680:Veins / Q000000981:diagnostic imaging / Q000637:transplantation*