title: Squamous cell carcinoma arising from a nonhealing wound and osteomyelitis treated with Mohs micrographic surgery: a case study.
abstract: The treatment of choice for squamous cell carcinoma arising from chronic ulcer at the lower extremity has traditionally been amputation. Recently, Mohs micrographic surgery has been used as a limb-saving option in selected patients. One of these patients, a 69 year-old white male, presented with a two-year history of a progressive non-healing would and osteomyelitis. A four-month history of an enlarging mass within the ulcer suggested squamous cell carcinoma, which was confirmed by biopsies. The patient was treated with Mohs micrographic surgery for local eradication of the tumor, intravenous antibiotics, and skin grafting.
authors.affiliation: Department of Dermatology & Cutaneous Surgery, University of Miami, FL 33136, USA.
authors.forename: A
authors.initials: A
authors.lastname: Chang
authors.forename: J M
authors.initials: JM
authors.lastname: Spencer
authors.forename: R S
authors.initials: RS
authors.lastname: Kirsner
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000209:etiology* / Q000601:surgery*; D006801:Humans; D008297:Male; D015580:Mohs Surgery / Q000379:methods*; D010019:Osteomyelitis / Q000150:complications*; D012878:Skin Neoplasms / Q000209:etiology* / Q000601:surgery*; D014945:Wound Healing