title: A finite-element model predicts thermal damage in cutaneous contact burns.
abstract: Thermal injury results from exposure of skin elements to an externally applied heat source. Finite-element analysis of heat transfer in cutaneous burns allows for an accurate prediction of tissue time-temperature relationships throughout the exposed tissue. A two-dimensional, axisymmetric, finite-element model of a contact burn was constructed, and damage integrals were calculated by applying the Arrhenius equation to the time-temperature profiles at each point. The epidermis, dermis, and subcutaneous fat were modeled as uniform elements with distinct thermal properties. Heated aluminum blocks were applied to Yorkshire pigs for 10 to 80 seconds to produce contact burns. Wound biopsies taken at 1, 24, and 48 hours were examined histologically and measured for the depth of burn. A significant deepening of the gelatinized tissue was observed in tissue taken from 1 hour to 24 hours. The finite-element prediction of cutaneous contact burn damage correlated well with histologic observations in this porcine model.
authors.affiliation: Brigham and Women's Hospital, Boston Massachusetts 02115, USA.
authors.forename: D P
authors.initials: DP
authors.lastname: Orgill
authors.forename: M G
authors.initials: MG
authors.lastname: Solari
authors.forename: M S
authors.initials: MS
authors.lastname: Barlow
authors.forename: N E
authors.initials: NE
authors.lastname: O'Connor
mesh_terms: D000818:Animals; D002056:Burns / Q000145:classification / Q000473:pathology*; D003094:Collagen / Q000378:metabolism; D006358:Hot Temperature; D006801:Humans; D008962:Models, Theoretical; D012867:Skin / Q000293:injuries* / Q000473:pathology; D013552:Swine
chemical_list: D003094:Collagen