title: Postoperative respiratory function in children after abdominal surgery. A comparison of epidural and intramuscular morphine analgesia.
abstract: Thirty children undergoing urological and abdominal surgery were entered into a randomised trial comparing the effects of epidural and intramuscular morphine on postoperative respiratory function. The forced vital capacity and the forced expired volume in 1 s were measured before and 6 h after surgery and on each of the following seven days. Significant decreases (p < 0.01) in forced vital capacity and forced expired volume in 1 s were seen after surgery. After the first postoperative day, a gradual recovery in pulmonary function was observed but the measured parameters had not returned to their pre-operative control values by the end of the study. There were no statistically significant differences between the two groups during the study with respect to forced vital capacity and forced expired volume in 1 s. The quality of analgesia was better in the epidural morphine group than in the intramuscular morphine group. The incomplete recovery of pulmonary function suggests that pain is not the only cause of postoperative respiratory changes in these patients.
authors.affiliation: Department of Anaesthesia, Hospital Clinic, Barcelona, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Chabas
authors.forename: C
authors.initials: C
authors.lastname: Gomar
authors.forename: A
authors.initials: A
authors.lastname: Villalonga
authors.forename: X
authors.initials: X
authors.lastname: Sala
authors.forename: P
authors.initials: P
authors.lastname: Taura
mesh_terms: D000005:Abdomen / Q000601:surgery*; D000293:Adolescent; D015360:Analgesia, Epidural; D000701:Analgesics, Opioid / Q000008:administration & dosage* / Q000627:therapeutic use; D002648:Child; D005260:Female; D005541:Forced Expiratory Volume / Q000187:drug effects; D006801:Humans; D007273:Injections, Intramuscular; D008297:Male; D009020:Morphine / Q000008:administration & dosage* / Q000627:therapeutic use; D010149:Postoperative Pain / Q000188:drug therapy* / Q000503:physiopathology; D011184:Postoperative Period; D015656:Respiratory Mechanics / Q000187:drug effects*; D014797:Vital Capacity / Q000187:drug effects
chemical_list: D000701:Analgesics, Opioid; D009020:Morphine