[A case of mucocutaneous leishmaniasis treated with success with a low dose of pentavalent antimonial].
The authors report a case of a 89 years-old woman with mucocutaneous leishmaniasis and previous diabetes mellitus and high blood pressure, who had been treated with allopurinol for 10 months without healing of lesions. Afterwards, she has been treated with meglumine antimonate, "glucantime" for 4 days, with a total dose 2,380 mg of Sbv, but developed cardiac side effects and hypokalemia, hence the treatment was withdrawn. However, this patient developed total clinical regression of lesions, in spite of she has been received low dose of this drug.
Amato
V S
VS
Departamento de Doenças Infecciosas e Parasitárias do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo.
de Oliveira
L S
LS
Silva
A C
AC
Machado
F R
FR
Amato
J G
JG
Nicodemo
A C
AC
Amato Neto
V
V
D000368:Aged; D000369:Aged, 80 and over; D000981:Antiprotozoal Agents / Q000008:administration & dosage*; D005148:Facial Dermatoses / Q000097:blood / Q000188:drug therapy* / Q000469:parasitology; D005260:Female; D006801:Humans; D007897:Leishmaniasis, Mucocutaneous / Q000097:blood / Q000188:drug therapy*; D008536:Meglumine / Q000008:administration & dosage*; D000077485:Meglumine Antimoniate; D009942:Organometallic Compounds / Q000008:administration & dosage*
D000981:Antiprotozoal Agents; D009942:Organometallic Compounds; D008536:Meglumine; D000077485:Meglumine Antimoniate
Um caso de leishmaniose cutâneo-mucosa tratado com sucesso com baixa dose de antimonial pentavalente.