Sugarhydrazones of 2-hydrazinoquinolines and their antimicrobial activity.
Sugar hydrazones from 2-hydrazinoquinoline, 2-hydrazino-6-methyllepidine, 6-chloro-2-hydrazino lepidine, 7-chloro-2-hydrazinolepidine, and 7-chloro-2-hydrazino-3-nitroquinoline were prepared. Their acetylation, benzoylation, periodate oxidation, oxidation with lead tetraacetate and bromination have been investigated. The antimicrobial activities of the hydrazones were evaluated. Some compounds showed moderate activity.
Khodair
A I
AI
Chemistry Department, Faculty of Science, Suez Canal University, Ismailia, Egypt.
Ibrahim
E S
ES
Diab
A M
AM
Abd-el Aziz
M M
MM
Omar
B M
BM
el Ashry
E S
ES
D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D003470:Culture Media; D006835:Hydrazones / Q000138:chemical synthesis* / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D011804:Quinolines / Q000138:chemical synthesis* / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D003470:Culture Media; D006835:Hydrazones; D011804:Quinolines