title: Treatment of hemoglobin Bart's hydrops with bone marrow transplantation.
abstract: A 21-month-old girl with hemoglobin Bart's hydrops received bone marrow transplantation (BMT) from a matched sibling. No major BMT-related complications developed. Hemoglobin levels remained greater than 10 gm/dl for 20 months without blood transfusion support despite the presence of residual host hemopoietic cells from 2 months after BMT. We suggest consideration of this therapeutic option for surviving patients.
authors.affiliation: Department of Pediatrics, Prince of Wales Hospital, Chinese University of Hong Kong.
authors.forename: K W
authors.initials: KW
authors.lastname: Chik
authors.forename: M M
authors.initials: MM
authors.lastname: Shing
authors.forename: C K
authors.initials: CK
authors.lastname: Li
authors.forename: T F
authors.initials: TF
authors.lastname: Leung
authors.forename: K S
authors.initials: KS
authors.lastname: Tsang
authors.forename: H L
authors.initials: HL
authors.lastname: Yuen
authors.forename: S B
authors.initials: SB
authors.lastname: Cheng
authors.forename: P M
authors.initials: PM
authors.lastname: Yuen
mesh_terms: D016026:Bone Marrow Transplantation; D005260:Female; D005914:Globins / Q000235:genetics; D006455:Hemoglobins, Abnormal / Q000235:genetics; D006801:Humans; D007223:Infant; D019172:Transplantation Conditioning; D017085:alpha-Thalassemia / Q000097:blood / Q000235:genetics / Q000628:therapy*
chemical_list: D006455:Hemoglobins, Abnormal; D005914:Globins; C030448:hemoglobin Bart's