[Comparative analysis of the action of antibodies to dopamine and serotonin on the functional activity of T- and B-lymphocytes and peritoneal macrophages].
As shown in experiments on mice C57B1/6, systemic intraperitoneal injection of serotonin antibodies in a dose 25 mg/kg or their introduction into cell culture in a dose 10(-7)M attenuates proliferative response of lymphocytes on PWM-induced stimulation, while functional activity of macrophages is stimulated. Antibodies to dopamine neither in systemic nor in cell culture introduction cause noticeable changes in lymphocytes proliferative response to their PWM and ConA mitogen stimulation. Phagocytic activity of peritoneal macrophages was also unchanged.
Davydova
T V
TV
Evseev
V A
VA
Fomina
V G
VG
Basharova
L A
LA
Mikovskaia
O I
OI
D000818:Animals; D000906:Antibodies / Q000276:immunology*; D001402:B-Lymphocytes / Q000276:immunology*; D004298:Dopamine / Q000276:immunology*; D017737:Macrophages, Peritoneal / Q000276:immunology*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D012701:Serotonin / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*
D000906:Antibodies; D012701:Serotonin; D004298:Dopamine
Sravnitel'nyĭ analiz deĭstviia antitel k dopaminu i serotoninu na funktsional'nuiu aktivnost' T-, B-limfotsitov i peritoneal'nykh makrofagov.