Risperidone-induced galactorrhea associated with a prolactin elevation.
We report on the occurrence of galactorrhea associated with a prolactin elevation within weeks of treatment with risperidone. One of our patients was switched to a typical antipsychotic, with an improvement in the galactorrhea. The other patient was continued on risperidone due to a robust response, while her galactorrhea was partially treated with bromocriptine. The mechanism of prolactin elevation with risperidone is unclear. These cases suggest the need for further studies.
Popli
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Porter Starke Counseling Centers & Porter Memorial Hospital, Valparaiso, Indiana 46383, USA.
Gupta
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Rangwani
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D000328:Adult; D014150:Antipsychotic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D005260:Female; D005687:Galactorrhea / Q000097:blood / Q000139:chemically induced*; D006801:Humans; D011388:Prolactin / Q000097:blood / Q000187:drug effects*; D011618:Psychotic Disorders / Q000188:drug therapy*; D018967:Risperidone / Q000008:administration & dosage / Q000009:adverse effects*
D014150:Antipsychotic Agents; D011388:Prolactin; D018967:Risperidone