Low symptomatic load in Crohn's disease with surgery and medicine as complementary treatments.
BACKGROUND
The treatment of Crohn's disease has changed owing to the recognition of its chronicity. Medical maintenance treatment and limited resections have evolved as major concepts of management, regarded as complementary, and both aim at reducing the symptoms.


METHODS
We investigated the symptomatic load in Crohn's disease as reflected in a cross-sectional study of the symptom index, physicians' assessment, and the patients' perception of health. A cohort of 212 patients from the primary catchment area and 125 referred patients were studied.


RESULTS
Of catchment area patients, 83% were receiving medication, and the annual rate of abdominal surgery was 5.7%. Corresponding figures for the referred patients were 82% and 10.3%. According to the symptom index, 87% of catchment area patients were in remission or had only mild symptoms; according to the physicians' assessment, 90% were. The patients' median perception of health was 90% of perfect health according to the visual analogue scale. The figures were similar for referred patients, except that referrals were considered more diseased by the physician.


CONCLUSIONS
The great majority of patients with Crohn's disease are able to live in remission or experience only mild symptoms.
Andersson
P
P
Dept. of Medico-Surgical Gastroenterology, University Hospital, Linköping, Sweden.
Olaison
G
G
Bodemar
G
G
Almer
S
S
Arvidsson
M
M
Dabrosin-Söderholm
J
J
Nyström
P O
PO
Smedh
K
K
Ström
M
M
Sjödahl
R
R
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D015331:Cohort Studies; D017281:Cost of Illness; D003424:Crohn Disease / Q000188:drug therapy* / Q000453:epidemiology / Q000523:psychology / Q000601:surgery*; D003430:Cross-Sectional Studies; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D015995:Prevalence; D011446:Prospective Studies; D012720:Severity of Illness Index; D013548:Sweden / Q000453:epidemiology; D016896:Treatment Outcome
D000893:Anti-Inflammatory Agents