title: Surgical management of local and regional recurrent head and neck squamous cell carcinoma.
abstract: During 1997 more than 40,000 Americans developed a squamous cancer of the upper aerodigestive tract. Surgery and radiation therapy may have been used alone or together, with reasonable prospects for curing them of disease. The majority of patients whose cancer cannot be controlled are confronted with local or regional recurrence. Such recurrences often occur in sites of the head and neck that are suited to early detection during an office examination. Hence, many are treatable with curative intent. This review addresses various surgical approaches to these difficult management problems.
authors.affiliation: Fox Chase Cancer Center, Department of Surgical Oncology, Philadelphia, PA 19111, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Watson
authors.forename: J A
authors.initials: JA
authors.lastname: Ridge
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000601:surgery* / Q000628:therapy; D003131:Combined Modality Therapy; D006258:Head and Neck Neoplasms / Q000401:mortality / Q000601:surgery* / Q000628:therapy; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery; D007825:Laryngectomy; D008207:Lymphatic Metastasis; D009062:Mouth Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery; D009303:Nasopharyngeal Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery; D037981:Neck Dissection; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery*; D010166:Palliative Care; D010610:Pharyngeal Neoplasms / Q000401:mortality / Q000532:radiotherapy / Q000601:surgery; D018714:Radiotherapy, Adjuvant; D012074:Remission Induction; D016879:Salvage Therapy