Disseminated histoplasmosis in an 'immunocompetent' child.
A rare case of severe disseminated histoplasmosis in a 7-year-old boy with apparently normal immune function is described. Current recommendations for diagnostic investigations, monitoring and the treatment of this disease with amphotericin B and itraconazole are reviewed.
Daubenton
J D
JD
Department of Paediatrics and Child Health, University of Cape Town.
Beatty
D W
DW
D000666:Amphotericin B / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002648:Child; D006658:Histoplasma / Q000302:isolation & purification; D006660:Histoplasmosis / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology*; D006801:Humans; D007121:Immunocompetence; D017964:Itraconazole / Q000627:therapeutic use; D007654:Ketoconazole / Q000627:therapeutic use; D008297:Male; D014640:Vancomycin / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D017964:Itraconazole; D014640:Vancomycin; D000666:Amphotericin B; D007654:Ketoconazole