Biologic prognostic factors in ovarian cancer: a review.
The need of foreseeing the prognosis of ovarian cancer beyond the limits of classical methods based on clinical and histopathological staging has recently caused great interest in a large number of biologic prognostic markers. Studies concern proliferation associated proteins, suppressor genes, abnormal expressions of growth factors, cytokins, and many more. Here some of the most recent and promising factors being studied are described together with their significance for future clinical application.
Framarino dei Malatesta
M L
ML
III Clinica Ostetrica e Ginecologica, Università la Sapienza-Umberto I, Roma, Italy.
Veneziano
M
M
Peppicelli
M
M
Lanzi
G
G
Marzetti
L
L
D014408:Biomarkers, Tumor / Q000032:analysis*; D002277:Carcinoma / Q000737:chemistry / Q000175:diagnosis* / Q000401:mortality; D005260:Female; D005786:Gene Expression Regulation; D006801:Humans; D007150:Immunohistochemistry; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000737:chemistry / Q000175:diagnosis* / Q000401:mortality; D017354:Point Mutation; D011379:Prognosis; D012680:Sensitivity and Specificity; D015996:Survival Rate; D014407:Tumor Cells, Cultured / Q000737:chemistry
D014408:Biomarkers, Tumor