Serum lipoprotein(a) and cardiovascular disease in non-insulin-dependent diabetes mellitus.
OBJECTIVE
To examine whether lp(a) can explain a) the increased cardiovascular morbidity in patients with non-insulin-dependent diabetes mellitus (NIDDM) and b) the wide variation in the tendency for such complications to develop in the patients.


METHODS
Cross-sectional study.


METHODS
General practice in a local community in Norway.


METHODS
One hundred and thirty NIDDM patients and a reference group drawn from a twin study.


METHODS
Lp(a), self-reported cardiovascular disease, urinary albumin excretion.


RESULTS
The level of lp(a) was equally distributed in our NIDDM population and a reference group. We found no association between lp(a) and self-reported cardiovascular disease and urinary albumin excretion (UAE).


CONCLUSIONS
Lp(a) cannot explain the increased risk for cardiovascular disease in NIDDM patients, nor can it explain the variation in the tendency for such complications to develop.
Furuseth
K
K
Institute of General Practice and Community Medicine, University of Oslo, Norway.
Berg
K
K
Hanssen
K F
KF
Rutle
O
O
Bruusgaard
D
D
Vaaler
S
S
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000419:Albuminuria / Q000150:complications; D002318:Cardiovascular Diseases / Q000150:complications*; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D017270:Lipoprotein(a) / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009664:Norway / Q000453:epidemiology; D012307:Risk Factors
D017270:Lipoprotein(a)