title: A mathematical model for the assessment of hemodynamic parameters using quantitative contrast echocardiography.
abstract: A mathematical model for the assessment of hemodynamic parameters using quantitative echocardiography is presented. The method involves the intravenous injection of an ultrasonic echo contrast agent. The relative enhancement of the backscattered ultrasound intensity is measured as a function of time (the time-intensity curve). From this measurement, the volume flow rate (cardiac output) and the mixing volume are calculated. Relevant acoustic properties of the ultrasound contrast agent are discussed. An in vitro experiment is performed to corroborate the theory presented.
authors.affiliation: Department of Medicine, University of Rochester, NY 14642, USA. xucai_chen@urmc.rochester.edu
authors.forename: X
authors.initials: X
authors.lastname: Chen
authors.forename: K Q
authors.initials: KQ
authors.lastname: Schwarz
authors.forename: D
authors.initials: D
authors.lastname: Phillips
authors.forename: S D
authors.initials: SD
authors.lastname: Steinmetz
authors.forename: R
authors.initials: R
authors.lastname: Schlief
mesh_terms: D002138:Calibration; D003287:Contrast Media; D004452:Echocardiography; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008955:Models, Cardiovascular; D017711:Nonlinear Dynamics; D019047:Phantoms, Imaging; D015203:Reproducibility of Results
chemical_list: D003287:Contrast Media