title: Parotid gland swelling in HIV diffuse infiltrative CD8 lymphocytosis syndrome.
abstract: HIV can affect salivary gland tissue. Parotid swellings have been observed in a subset of patients who are HIV-positive; the swellings are the result of a condition that has been termed diffuse infiltrative CD8 lymphocytosis syndrome. Initially the glandular enlargement results from a massive CD8 cell lymphoproliferation, but with time lymphoepithelial cysts become manifest. Two case reports are presented to illustrate this progression of diffuse infiltrative CD8 lymphocytosis.
authors.affiliation: Division of Oral and Maxillofacial Surgery, Columbia University School of Dental and Oral Surgery and Columbia Presbyterian Medical Center, New York, NY 10032, USA.
authors.forename: L
authors.initials: L
authors.lastname: Mandel
authors.forename: D
authors.initials: D
authors.lastname: Kim
authors.forename: C
authors.initials: C
authors.lastname: Uy
mesh_terms: D000328:Adult; D016516:CD4-CD8 Ratio; D018414:CD8-Positive T-Lymphocytes / Q000473:pathology*; D002455:Cell Division; D003560:Cysts / Q000473:pathology; D006679:HIV Seropositivity / Q000473:pathology*; D006801:Humans; D008218:Lymphocytosis / Q000473:pathology*; D008297:Male; D010309:Parotitis / Q000473:pathology*; D013577:Syndrome