title: Cerebral venous thrombosis in pregnancy: the role of protein S deficiency.
abstract: We report a 20 year-old, 28 week-pregnant woman, who developed superior sagittal sinus thrombosis, associated with a decreased free protein S level. Her father, who had been a stroke victim, had also significantly lower level of protein S. In very rare cases, a congenital or acquired protein S deficiency leads to cerebral venous thrombosis. The detection of such abnormalities has major practical consequences for the long-term management of patients to prevent further thrombotic episodes.
authors.affiliation: Department of Neurology, Gülhane Medical School, Ankara, Turkey.
authors.forename: Z
authors.initials: Z
authors.lastname: Gökçil
authors.forename: Z
authors.initials: Z
authors.lastname: Odabasi
authors.forename: O
authors.initials: O
authors.lastname: Vural
authors.forename: M
authors.initials: M
authors.lastname: Yardim
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic; D018455:Protein S Deficiency / Q000503:physiopathology*; D012851:Sinus Thrombosis, Intracranial / Q000175:diagnosis / Q000503:physiopathology*