Fine needle aspiration cytology of a solid papillary carcinoma of the breast. A case report with immunohistochemical studies.
BACKGROUND
Solid papillary carcinoma of the breast was recently described. This tumor display distinctive clinical and morphologic features. It is an intraductal papillary carcinoma frequently associated with mucinous carcinoma and infiltrating ductal carcinoma not otherwise specified.


METHODS
Fine needle aspiration cytology (FNAC) of a solid papillary carcinoma of the right breast in an 82-year-old female, demonstrated a cellular specimen of discohesive, small, uniform and ovoid tumor cells, with occasional loose cluster. The cytoplasm was abundant and finely granular. The nuclei were round, without marked atypia. The nucleoli were inconspicuous. SCant mucinous material was present. The diagnosis was confirmed histologically and immunohistochemically.


CONCLUSIONS
The cytologic aspects of solid papillary carcinoma of the breast suggest a carcinoma with endocrine differentiation and a weak mucinous component.
Boran
M D
MD
Department of Pathology, Hôpital de la Croix Rousse, Lyon, France.
de Saint Hilaire
P J
PJ
Leveugle-Pin
J
J
Patricot
L M
LM
Thivolet-Béjui
F
F
D000368:Aged; D000369:Aged, 80 and over; D001707:Biopsy, Needle; D001940:Breast / Q000473:pathology*; D001943:Breast Neoplasms / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D002291:Carcinoma, Papillary / Q000737:chemistry / Q000175:diagnosis / Q000473:pathology*; D002454:Cell Differentiation; D005260:Female; D006801:Humans; D009077:Mucins / Q000032:analysis; D009363:Neoplasm Proteins / Q000032:analysis; D014411:Neoplastic Stem Cells / Q000473:pathology
D009077:Mucins; D009363:Neoplasm Proteins