Effect of a high linoleic acid diet on delta 9-desaturase activity, lipogenesis and lipid composition of pig subcutaneous adipose tissue.
The effects of three diets were compared: a high linoleic acid diet (diet M containing 4% maize oil), diet T containing 4% beef tallow, and C, a conventional control diet, on delta 9-desaturase activity and lipogenesis in pig subcutaneous adipose tissue. Diet M increased lipogenesis (estimated from the activities of acetyl-CoA-carboxylase, malic enzyme and glucose-6-phosphate dehydrogenase), and decreased delta 9-desaturase activity, in comparison to the other diets. Linoleic acid content was higher in the pigs fed diet M than in the other pigs (amounting to 26% of total tissue fatty acids versus 15%, respectively). The lower monounsaturated fatty acid content in adipose tissue of pigs fed diet M compared to pigs fed other diets could be associated with the lower delta 9-desaturase activity and the lower oleic acid content of diet M. The present study suggests that delta 9-desaturase could be involved in the regulation of monounsaturated fatty acid content and hence in the quality of pig adipose tissue.
Kouba
M
M
Ensa de Rennes, France. kouba@st-gilles.rennes.inra.fr
Mourot
J
J
D000103:Acetyl-CoA Carboxylase / Q000378:metabolism; D000273:Adipose Tissue / Q000737:chemistry*; D000818:Animals; D004042:Dietary Fats, Unsaturated / Q000008:administration & dosage*; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D019787:Linoleic Acid / Q000008:administration & dosage*; D008041:Linoleic Acids; D008055:Lipids / Q000032:analysis* / Q000096:biosynthesis*; D008291:Malate Dehydrogenase / Q000378:metabolism; D008297:Male; D019301:Oleic Acid / Q000008:administration & dosage; D013230:Stearoyl-CoA Desaturase / Q000378:metabolism*; D013552:Swine / Q000378:metabolism*
D004042:Dietary Fats, Unsaturated; D008041:Linoleic Acids; D008055:Lipids; D019301:Oleic Acid; D019787:Linoleic Acid; D008291:Malate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D013230:Stearoyl-CoA Desaturase; D000103:Acetyl-CoA Carboxylase