1D Determination of Long-Range Heteronuclear Coupling Constants by Gradient Enhanced SIMBA.
Two 1H-detected one-dimensional gradient enhanced experiments and corresponding reference experiments are proposed for the measurement of heteronuclear long-range nJCH coupling constants in organic molecules. These experiments use inverse detection and selective carbon excitation, provide excellent suppression of protons not coupled to 13C, and are able to measure couplings from regions that are crowded in both the proton and carbon frequency ranges. The experiments are applied to determine the long-range nJCH couplings in the sucrose molecule, including coupling across the glycosidic linkage. These pulse sequences are shown to provide accurate and efficient measurements of coupling constants that would be difficult or time-consuming to measure by other techniques. Copyright 1998 Academic Press.
Vogt
FG
Department of Chemistry, Pennsylvania State University, University Park, Pennsylvania, 16802
Benesi
AJ