title: [Paranasal mucormycosis with involvement of the sphenoid sinus].
abstract: Mucormycosis with hemipansinusitis and left orbital involvement was observed in a 66-year-old diabetic woman. Diagnosis was confirmed by mycology and pathology examinations. The patient was treated surgically with wide exeresis of necrotic tissue and medically with amphotericin B and insulin. Cure was obtained after three months of treatment at the cost of retraction of the left nostril due to infectious lysis and resection of the nasal infrastructure. The sinus involvement was exceptional compared with reports in the literature. Mucormycosis is an uncommon condition caused by opportunistic infection in immunodepressed subjects. The causal agent is a fungus belonging to the Rhizopus, Absidia or Mucor genera. Prognosis is poor with overall mortality reaching 50%.
authors.affiliation: Service de chirurgie maxillo-faciale, Chirurgie Plastique et Esthétique, Stomatologie, CHU St Etienne, Hôpital de Bellevue.
authors.forename: R
authors.initials: R
authors.lastname: Sokolo
authors.forename: T
authors.initials: T
authors.lastname: Lefort
authors.forename: F
authors.initials: F
authors.lastname: Soulhiard
authors.forename: J M
authors.initials: JM
authors.lastname: Dumollard
authors.forename: P
authors.initials: P
authors.lastname: Seguin
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000188:drug therapy; D005260:Female; D006801:Humans; D007328:Insulin / Q000627:therapeutic use; D007654:Ketoconazole / Q000627:therapeutic use; D009091:Mucormycosis / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D009668:Nose Diseases / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D009916:Orbital Diseases / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D015524:Sphenoid Sinusitis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery
chemical_list: D000935:Antifungal Agents; D007328:Insulin; D000666:Amphotericin B; D007654:Ketoconazole
vernacular_title: Mucormycose para-nasale avec atteinte du sinus sphénoïdal.