title: Laparoscopic versus conventional colorectal resection: a prospective randomised study of postoperative ileus and early postoperative feeding.
abstract: BACKGROUND
  A shorter duration of postoperative ileus and earlier oral alimentation of patients may be a clinically relevant benefit of laparoscopic compared with conventional colorectal resection.
  
  
  METHODS
  A total of 60 patients were randomised to either laparoscopic (n=30) or conventional (n=30) resection of colorectal tumours. Major endpoints were the postoperative time to the first bowel movement and the time until oral feeding without parenteral alimentation was tolerated. Minor endpoints were the postoperative interval to the first peristalsis and first passage of flatus, the distribution of radio-opaque markers in abdominal radiographs on day 3 and day 5 and the incidence of postoperative vomiting.
  
  
  RESULTS
  Age, gender. ASA-classification and type of resection were comparable in the two groups. Peristalsis was first noticed 26+/-9 h after laparoscopic and 38+/-17 h after conventional colorectal resection (P<0.01). First flatus occurred 50+/-19 h after laparoscopic and 79+/-21 h after conventional surgery (P<0.01). The incidence of postoperative vomiting was similar in both groups. Three days after surgery radio-opaque markers were found more often in the right colon (P<0.01) and less often in the small intestine (P<0.05) in laparoscopic compared with conventional patients. Five days after laparoscopic surgery, more markers had reached the left colon (P<0.05). The first bowel movement occurred 70+/-32 h after laparoscopic and 91+/-22 h after conventional resection (P<0.01). Oral feeding without additional parenteral alimentation was tolerated 3.3+/-0.7 days after laparoscopic and 5.0+/-1.5 days after conventional surgery (P<0.01).
  
  
  CONCLUSIONS
  The shorter duration of postoperative ileus allows earlier restoration of oral feeding after laparoscopic compared with conventional colorectal resection and therefore increases quality of life immediately after resection of colorectal tumours.
authors.affiliation: Department of Surgery, Medical Faculty of the Humboldt-University at Berlin, Charité, Germany.
authors.forename: W
authors.initials: W
authors.lastname: Schwenk
authors.forename: B
authors.initials: B
authors.lastname: Böhm
authors.forename: O
authors.initials: O
authors.lastname: Haase
authors.forename: T
authors.initials: T
authors.lastname: Junghans
authors.forename: J M
authors.initials: JM
authors.lastname: Müller
mesh_terms: D000368:Aged; D003082:Colectomy; D015179:Colorectal Neoplasms / Q000601:surgery*; D004750:Enteral Nutrition; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology*; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology*; D011446:Prospective Studies; D012086:Reoperation; D016896:Treatment Outcome