title: [A case of pulmonary infiltration with eosinophilia caused by Ascaris suum].
abstract: A 46-year old man was admitted to our hospital with dry cough and diarrhea. His chest CT showed diffuse subpleural small nodular shadows. Eosinophilia and an increase of serum IgE were detected. Eosinophils were also increased in BALF. An antibody against Ascaris suum was positive in serum while other causes of eosinophilia (e. g., drugs, fungus, collagen disease) were absent. Ivermectin was administered and the diarrhea improved within 3 days. The abnormal chest shadows and dry cough disappeared 3 months later. Pulmonary infiltration with eosinophilia (PIE) syndrome caused by Ascaris suum was diagnosed because of the clinical course and serum examination results. Recently, zoonoses are increasing with the boom of oversea travel and "natural" foods. We report a case of PIE syndrome caused by Ascaris suum and describe the clinical features and the social significance including the origin of this disease.
authors.affiliation: Department of Respiratory Medicine, Minami-kyushu National Hospital, Kagoshima, Japan.
authors.forename: W
authors.initials: W
authors.lastname: Matsuyama
authors.forename: A
authors.initials: A
authors.lastname: Mizoguchi
authors.forename: F
authors.initials: F
authors.lastname: Iwami
authors.forename: M
authors.initials: M
authors.lastname: Kawabata
authors.forename: M
authors.initials: M
authors.lastname: Osame
mesh_terms: D000818:Animals; D000909:Antibodies, Helminth / Q000032:analysis; D001196:Ascariasis / Q000175:diagnosis; D017165:Ascaris suum / Q000276:immunology; D004797:Enzyme-Linked Immunosorbent Assay; D016266:Food Parasitology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011657:Pulmonary Eosinophilia / Q000469:parasitology*
chemical_list: D000909:Antibodies, Helminth