Transendoscopic chemical ablation of progressive ethmoidal hematomas in standing horses.
OBJECTIVE
To examine the response of horses with progressive ethmoidal hematoma (PEH) to intralesional injection of 4% formaldehyde solution.


METHODS
Nasal passages of horses affected with PEH were examined endoscopically at different intervals to determine the effects of intralesional injection of formaldehyde solution.


METHODS
21 horses with PEH.


METHODS
PEHs were injected transendoscopically with 4% formaldehyde solution. Horses were examined endoscopically and retreated at different intervals until the PEH was eliminated or was so small that reinjection was not possible.


RESULTS
Lesions diminished significantly in size or were eliminated after 1 to 18 injections (median, 5; mean, 7.0 +/- 5.62). Seventeen lesions (60.7%) resolved completely after 1 to 18 injections (median, 5; mean, 7.2 +/- 5.71). Five lesions decreased markedly in size but did not resolve after receiving 1 to 18 injections (median, 5; mean, 7.6 +/- 6.66). Injection of these lesions was discontinued 4.0 to 25.1 months (median, 9.5; mean, 11.02 +/- 8.446) after the first injection. The PEH of one horse was removed surgically after one injection. Three horses, one with bilateral PEH, were lost to follow-up. One horse developed signs of laminitis. No other complications were observed.


CONCLUSIONS
Horses with a PEH can be treated effectively by transendoscopic, intralesional injection of 4% formaldehyde solution.


CONCLUSIONS
Ablation of PEH using formaldehyde solution avoids general anesthesia and problems associated with ablation by conventional surgery or laser.
Schumacher
J
J
Department of Large Animal Medicine and Surgery, Texas Veterinary Medical Center, College of Veterinary Medicine, College Station, USA.
Yarbrough
T
T
Pascoe
J
J
Woods
P
P
Meagher
D
D
Honnas
C
C
D000818:Animals; D004724:Endoscopy / Q000662:veterinary; D005005:Ethmoid Sinus; D005260:Female; D005557:Formaldehyde / Q000008:administration & dosage / Q000627:therapeutic use*; D006406:Hematoma / Q000628:therapy / Q000662:veterinary*; D006734:Horse Diseases / Q000628:therapy*; D006736:Horses; D015552:Injections, Intralesional / Q000662:veterinary; D008297:Male; D010254:Paranasal Sinus Diseases / Q000628:therapy / Q000662:veterinary*; D012996:Solutions; D016896:Treatment Outcome
D012996:Solutions; D005557:Formaldehyde