Low molecular weight heparin-induced skin necrosis occurring distant from injection sites and without thrombocytopenia.
In this paper we report a case of 76-year-old white male patient with skin necrosis induced by subcutaneous prophylactic administration of low-molecular-weight heparin (LMWH). Skin necrosis occurred distant from heparin injection sites and without concomitant thrombocytopenia. This is the first reported case presenting these clinical findings.
Tietge
U J
UJ
Department of Gastroenterology and Hepatology, Medizinische Hochschule Hannover, Germany.
Schmidt
H H
HH
Jäckel
E
E
Trautwein
C
C
Manns
M P
MP
D000368:Aged; D005343:Fibrinolytic Agents / Q000009:adverse effects*; D006495:Heparin, Low-Molecular-Weight / Q000009:adverse effects*; D006801:Humans; D007279:Injections, Subcutaneous; D008297:Male; D009336:Necrosis; D012867:Skin / Q000187:drug effects* / Q000473:pathology*; D013921:Thrombocytopenia
D005343:Fibrinolytic Agents; D006495:Heparin, Low-Molecular-Weight