Risk features for surgical-site infections in coronary artery bypass surgery.
OBJECTIVE
To identify preoperative and perioperative features that may lead to a risk of surgical-site infection (SSI) after coronary artery bypass surgery.


METHODS
884 patients who underwent coronary artery bypass grafting in 1992 and 1993 were studied. The associations between 23 preoperative and perioperative features and the presence of SSI at the donor site or in the chest area were evaluated by univariate analysis followed by multivariate logistic regression analysis.


METHODS
A university hospital.


RESULTS
172 patients (19.5%) either had an SSI recorded before discharge or had received antibiotics prescribed for a suspected SSI during the 1-month surveillance period after discharge. Multivariate logistic regression analysis showed an extreme body mass index (BMI; P=.015), female gender (P=.023), and chronic obstructive pulmonary disease (COPD; P=.030) to be independent risk features for SSI. The donor site was infected in 136 patients (15.4%), an event for which female gender (P=.003) was the only independent risk feature. Forty-seven patients (5.3%) had an SSI of the chest area, with diabetes (P=.003) and extreme BMI (P=.010) as independent risk features.


CONCLUSIONS
Extreme BMI, female gender, and COPD are highly significant independent predictors of the development of SSI. Female gender is a risk feature specifically for SSI at the donor site, whereas diabetes and extreme BMI predict it in the chest area.
Vuorisalo
S
S
Department of Surgery, University of Oulu, Finland.
Haukipuro
K
K
Pokela
R
R
Syrjälä
H
H
D019072:Antibiotic Prophylaxis; D015992:Body Mass Index; D001026:Coronary Artery Bypass; D003920:Diabetes Mellitus; D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D016015:Logistic Models; D008173:Lung Diseases, Obstructive; D008297:Male; D015999:Multivariate Analysis; D012307:Risk Factors; D012737:Sex Factors; D013503:Surgery Department, Hospital; D013530:Surgical Wound Infection / Q000453:epidemiology* / Q000517:prevention & control