title: Two cases of sleep-disordered breathing in climacteric.
abstract: Two cases of sleep disordered-breathing in climacteric were reported. Polysomnography including esophageal pressure (Pes) measurement was performed. Case 1 was diagnosed as upper airway resistance syndrome. Case 2 was diagnosed as obstructive sleep apnea syndrome, while many episodes of upper airway resistance also existed. Hormone replacement therapy improved clinical symptoms, and in case 1, Pes nadir was improved but incidence of arousals which was induced by breathing disturbances was not significantly changed. Sleep disordered-breathing should be suspected as a cause of sleep disorder even in females, especially in climacteric age. Pes measurement and evaluation of arousals is required. Hormone replacement therapy may release the upper airway resistance.
authors.affiliation: Department of Neuropsychiatry, Osaka University Medical School, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Watanabe
authors.forename: A
authors.initials: A
authors.lastname: Mikami
authors.forename: M
authors.initials: M
authors.lastname: Motonishi
authors.forename: H
authors.initials: H
authors.lastname: Honda
authors.forename: K
authors.initials: K
authors.lastname: Kyotani
authors.forename: S
authors.initials: S
authors.lastname: Uruha
authors.forename: K
authors.initials: K
authors.lastname: Terashima
authors.forename: Y
authors.initials: Y
authors.lastname: Teshima
authors.forename: Y
authors.initials: Y
authors.lastname: Sugita
mesh_terms: D000403:Airway Resistance / Q000187:drug effects / Q000502:physiology; D001143:Arousal / Q000187:drug effects / Q000502:physiology; D002979:Climacteric / Q000187:drug effects / Q000502:physiology*; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D008875:Middle Aged; D017286:Polysomnography; D012891:Sleep Apnea Syndromes / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*