title: Blood flux and venoarteriolar response of the skin in legs with chronic venous insufficiency measured at two different depths by using a double-wavelength laser Doppler technique.
abstract: The laser Doppler flux (LDF) and the venoarteriolar response (VAR) of the skin in legs with chronic venous insufficiency (CVI) was measured by using a new double-wavelength probe technique (543 nm and 780 nm). The recordings were taken in a recumbent and in a sitting position. Ten patients with CVI and 20 control subjects with healthy legs were investigated. The LDF was found to be significantly enhanced in a recumbent position at 543 nm and in a sitting position at 780 nm in legs with CVI compared with healthy legs (P<0.05 and P=0.02, respectively). The authors could not find the VAR to be impaired in either wavelength in legs with CVI compared with healthy legs. The double-wavelength probe technique makes it possible to record simultaneously the LDF in the superficial and deep layers of the skin on the same place in the leg.
authors.affiliation: The Medical Center of Lappeenranta, Finland.
authors.forename: K
authors.initials: K
authors.lastname: Malanin
authors.forename: P
authors.initials: P
authors.lastname: Vilkko
authors.forename: P J
authors.initials: PJ
authors.lastname: Kolari
mesh_terms: D000368:Aged; D002908:Chronic Disease; D005260:Female; D006801:Humans; D017078:Laser-Doppler Flowmetry / Q000379:methods*; D007866:Leg / Q000098:blood supply*; D008297:Male; D008875:Middle Aged; D012867:Skin / Q000098:blood supply* / Q000503:physiopathology; D014689:Venous Insufficiency / Q000503:physiopathology*