Lithium enhancement of the prolactin response to 5-hydroxytryptophan is not reversible by inositol.
1. Two hundred male albino Sprague-Dawley rats were studied for the lithium and/or inositol effect on 5-HTP induced prolactin release. 2. Lithium demonstrated a clear augmentation of 5-HTP induced prolactin levels, however no effect of inositol was demonstrated on lithium augmentation of 5-HTP induced prolactin release.
Gavrilov
V
V
Ministry of Health Mental Health Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Levine
J
J
Agam
G
G
Belmaker
R H
RH
D006916:5-Hydroxytryptophan / Q000494:pharmacology*; D000818:Animals; D014150:Antipsychotic Agents / Q000494:pharmacology*; D004357:Drug Synergism; D007294:Inositol / Q000494:pharmacology*; D008094:Lithium / Q000494:pharmacology*; D008297:Male; D011388:Prolactin / Q000378:metabolism*; D051381:Rats; D017207:Rats, Sprague-Dawley
D014150:Antipsychotic Agents; D007294:Inositol; D011388:Prolactin; D008094:Lithium; D006916:5-Hydroxytryptophan