title: [Continuous spike-wave activity during sleep. Electroencephalographic and clinical features].
abstract: Seventeen children were retrospectively evaluated. They exhibited continuous spike-wave activity during slow wave sleep (CSWS). Five of these had only speech problems and seizures (Landau-Kleffner syndrome) (group 1). The other cases had developmental milestones acquisition delay and/or mental retardation (group 2). Epileptic seizures were present in 11 of these, tetraparesis was observed in 5, hemiparesis in 2, microcephaly in 2 and behavior disturbances in 4 cases. The electroencephalogram showed in all cases diffuse CSWS. Group 1 showed diffuse activity, at times accentuated in the centrotemporal region (4/5). Group 2 had widespread discharges, including multifocal activity (5/12), sometimes with anterior predominance (7/12). We concluded that CSWS is a non specific electrographic pattern observed in some types of epilepsy in childhood that have different clinical presentation. It has however some topographic differentiation, depending upon the lesional sites.
authors.affiliation: Departamento de Neurologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HC/FMSUP), Brasil.
authors.forename: L M
authors.initials: LM
authors.lastname: Guilhoto
authors.forename: L R
authors.initials: LR
authors.lastname: Machado-Haertel
authors.forename: M L
authors.initials: ML
authors.lastname: Manreza
authors.forename: A J
authors.initials: AJ
authors.lastname: Diament
mesh_terms: D001921:Brain / Q000503:physiopathology*; D002648:Child; D002675:Child, Preschool; D004569:Electroencephalography; D005260:Female; D006801:Humans; D007223:Infant; D018887:Landau-Kleffner Syndrome / Q000175:diagnosis* / Q000503:physiopathology; D008297:Male; D012189:Retrospective Studies; D012890:Sleep / Q000502:physiology*
vernacular_title: Espícula-onda contínua durante o sono. Aspectos clínicos e eletrencefalográficos.