Lack of association between dopamine transporter gene polymorphisms and delusional disorder.
Potential contributions of dopamine transporter (DAT) gene variants to delusional disorder were investigated using association analysis. DAT gene VNTR polymorphisms were assessed in 61 delusional patients and 54 normal controls. No differences were found in either genotypic or allelic distributions. These findings do not support relevant contributions of DAT gene variants to the pathogenesis of delusional disorder.
Persico
A M
AM
Department of NeuroPsychiatric Sciences, S. Raffaele Hospital, Milan, Italy. liucbm@iasi.rm.cnr.it
Catalano
M
M
D000328:Adult; D000368:Aged; D000483:Alleles; D002352:Carrier Proteins / Q000235:genetics*; D016022:Case-Control Studies; D050483:Dopamine Plasma Membrane Transport Proteins; D005260:Female; D005838:Genotype; D006801:Humans; D008297:Male; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D008875:Middle Aged; D018598:Minisatellite Repeats; D009419:Nerve Tissue Proteins; D011110:Polymorphism, Genetic; D012563:Schizophrenia, Paranoid / Q000235:genetics*
D002352:Carrier Proteins; D050483:Dopamine Plasma Membrane Transport Proteins; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; C493214:SLC6A3 protein, human