title: Mechanical properties of bioactive glasses, glass-ceramics and composites.
abstract: The application of bioactive glass and glass-ceramics has been widely documented over the past twenty years but the high modulus and low fracture toughness has made them less applicable for clinical, load bearing, applications. The development of non-resorbable polyethylene and polysulphone matrices for these materials has improved the mechanical properties. However, the primary concern of whether the bioactivity of the composites is reduced is still unresolved. The more recent development of resorbable carrier systems, dextran and collagen, for bioactive glasses does not introduce such problems, hence making this form of composite suitable for novel soft tissue applications. The development of a simple quality index has enabled some of the materials described within this paper to be ranked by their ability to replace bone, thus enabling possible new research directions to be emphasized.
authors.affiliation: Imperial College of Science, Technology and Medicine, London.
authors.forename: I D
authors.initials: ID
authors.lastname: Thompson
authors.forename: L L
authors.initials: LL
authors.lastname: Hench
mesh_terms: D001672:Biocompatible Materials; D001696:Biomechanical Phenomena; D002516:Ceramics / Q000737:chemistry; D003188:Composite Resins / Q000737:chemistry; D005898:Glass / Q000737:chemistry; D008422:Materials Testing; D013718:Tensile Strength
chemical_list: D001672:Biocompatible Materials; D003188:Composite Resins