title: Lung volume histograms after computed tomography of the chest with three-dimensional imaging as a method to substantiate successful surgical expansion of the rib cage in achondroplasia.
abstract: The authors describe a radiographic method to quantify a surgical procedure of thoracic expansion in a 2-year-old patient with achondroplasia, small chest cage, and severe restrictive lung disease. The patient had undergone three surgical procedures of thoracic expansion since birth. The authors utilized computer-generated lung volume histograms after spiral computed tomographic scanning and three-dimensional imaging of the lungs to calculate his lung volumes before and after the third surgical thoracic expansion. The lung volumes, calculated by the histograms, were 363 mL and 406 mL before and after surgery, respectively. This 40-mL difference in the patient's lung volumes (4 mL/kg) accounted for a significant clinical improvement. Lung volume histograms obtained by this radiographic method are very helpful in substantiating a successful surgical chest expansion or provide an explanation for an unsuccessful repair.
authors.affiliation: Division of Critical Care Medicine, Schneider Children's Hospital, New Hyde Park, NY 11040, USA.
authors.forename: N
authors.initials: N
authors.lastname: Lugo
authors.forename: J
authors.initials: J
authors.lastname: Becker
authors.forename: H
authors.initials: H
authors.lastname: Van Bosse
authors.forename: W
authors.initials: W
authors.lastname: Campbell
authors.forename: B
authors.initials: B
authors.lastname: Evans
authors.forename: M
authors.initials: M
authors.lastname: Sagy
mesh_terms: D000130:Achondroplasia / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D002675:Child, Preschool; D006801:Humans; D007231:Infant, Newborn; D008173:Lung Diseases, Obstructive / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery*; D008176:Lung Volume Measurements / Q000379:methods*; D008297:Male; D012127:Respiratory Distress Syndrome, Newborn / Q000000981:diagnostic imaging / Q000209:etiology / Q000628:therapy; D012272:Ribs / Q000002:abnormalities / Q000601:surgery*; D012680:Sensitivity and Specificity; D019616:Thoracic Surgical Procedures / Q000379:methods; D014057:Tomography, X-Ray Computed