Synthesis of beta-tetrazolyl DL-alanine derivatives.
Interest in non-natural alpha-amino acids is growing because of their potential biological activity. We describe, in this paper, a synthesis of beta-tetrazolyl alpha-amino esters by action of 5-aryl tetrazoles, 2, on N-benzyloxycarbonyl di-dehydro methylalaninate, 3.
Alami
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Laboratoire de Chimie Organique, Faculté des Sciences Dhar El Mehraz, Université Sidi Mohamed Ben Abdellah, Fes Atlas, Morocco.
el Hallaoui
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A
Elachqar
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el Hajji
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S
Roumestant
M L
ML
Viallefont
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P
D000409:Alanine / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D000596:Amino Acids / Q000138:chemical synthesis*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D013777:Tetrazoles / Q000138:chemical synthesis*
D000596:Amino Acids; D013777:Tetrazoles; D000409:Alanine