title: New 4-thiazoline-2-hydrazono-1H-2-indolinones as possible antimicrobial agents.
abstract: In order to test their antimicrobial activity a series of new 3-[(3-substituted-4-methyl-5-carboxy/carbetoxy-4-thiazolin-2 - ylidene)hydrazono]-1H-2-indolinones (3a-i/4) were synthesized from the reaction of 3-(4-substituted-3-thiosemicarbazono-1H-2-indolinones (1a-I) with 2-chloroacetoacetic acid ethyl ester (2). All synthesized compounds were characterized by IR, 1H-NMR, EIMS and elementary analysis.
authors.affiliation: Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Istanbul, Turkey.
authors.forename: N
authors.initials: N
authors.lastname: Karali
authors.forename: N
authors.initials: N
authors.lastname: Terzioglu
authors.forename: A
authors.initials: A
authors.lastname: Gürsoy
authors.forename: G
authors.initials: G
authors.lastname: Otük
authors.forename: M
authors.initials: M
authors.lastname: Kiraz
authors.forename: Y
authors.initials: Y
authors.lastname: Yegenoglu
mesh_terms: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects*; D005658:Fungi / Q000187:drug effects*; D007211:Indoles / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D013844:Thiazoles / Q000138:chemical synthesis* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D007211:Indoles; D013844:Thiazoles