Variant in the regulatory subunit of phosphatidylinositol 3-kinase (p85alpha): preliminary evidence indicates a potential role of this variant in the acute insulin response and type 2 diabetes in Pima women.
Baier
L J
LJ
Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, Arizona 85016, USA. lbaier@phx.niddk.nih.gov
Wiedrich
C
C
Hanson
R L
RL
Bogardus
C
C
D000328:Adult; D001130:Arizona; D001786:Blood Glucose / Q000187:drug effects / Q000378:metabolism; D003924:Diabetes Mellitus, Type 2 / Q000201:enzymology* / Q000453:epidemiology / Q000235:genetics*; D005260:Female; D014644:Genetic Variation; D005838:Genotype; D005947:Glucose / Q000378:metabolism; D005951:Glucose Tolerance Test; D006801:Humans; D007198:Indians, North American / Q000235:genetics*; D007328:Insulin / Q000097:blood / Q000494:pharmacology*; D007333:Insulin Resistance / Q000235:genetics*; D046911:Macromolecular Substances; D019869:Phosphatidylinositol 3-Kinases / Q000737:chemistry / Q000235:genetics*; D017354:Point Mutation; D011110:Polymorphism, Genetic; D015995:Prevalence
D001786:Blood Glucose; D007328:Insulin; D046911:Macromolecular Substances; D019869:Phosphatidylinositol 3-Kinases; D005947:Glucose