title: [Captopril use in pregnancy and its effects on the fetus and the newborn: case report].
abstract: Angiotensin-converting enzyme (ACE) inhibitors have been widely used to control hypertension, but their use during gestation may result in fetal death, intra-uterine growth retardation, oligoamnium sequence, hypotension, acute renal failure and ductus arteriosus patency in the newborn. The aim of this case report is to highlight the risks of using this drug during gestation. The authors present a case of captopril use during pregnancy, whose newborn developed acute renal failure and ductus arteriosus patency early in the newborn period. This presentation strengthens the importance of not only monitoring amniotic fluid volume and fetal growth, but also, during the newborn period, control the weight gain, diuresis, systemic arterial pressure and renal function, mainly in the first 72 hours of life.
authors.affiliation: Berçário Anexo à Maternidade, Instituto da Crianca Prof. Pedro de Alcântara, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo.
authors.forename: L S
authors.initials: LS
authors.lastname: Sadeck
authors.forename: M
authors.initials: M
authors.lastname: Fernandes
authors.forename: S M
authors.initials: SM
authors.lastname: Silva
authors.forename: A A
authors.initials: AA
authors.lastname: Trindade
authors.forename: C Y
authors.initials: CY
authors.lastname: Chia
authors.forename: J L
authors.initials: JL
authors.lastname: Ramos
authors.forename: C R
authors.initials: CR
authors.lastname: Leone
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D000328:Adult; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000009:adverse effects*; D000959:Antihypertensive Agents / Q000009:adverse effects*; D002216:Captopril / Q000009:adverse effects*; D004374:Ductus Arteriosus, Patent / Q000139:chemically induced*; D005260:Female; D005333:Fetus / Q000187:drug effects*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy
chemical_list: D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D002216:Captopril
vernacular_title: Uso de captopril durante a gestação e suas repercussões sobre o feto e o recém-nascido: relato de caso.