title: Eight-and-a-half syndrome: one-and-a-half syndrome plus cranial nerve VII palsy.
abstract: Three cases of isolated one-and-a-half syndrome with facial nerve palsy related to infarction are presented. Magnetic resonance imaging in cases 1 and 2 was unremarkable, whereas magnetic resonance angiography demonstrated pathophysiologically significant vertebral basilar disease. Case 3 is unique due to its association with giant cell arteritis. Ipsilateral adduction improved to a greater extent than abduction in each case, perhaps providing insight into the exact localization of these lesions or selective vulnerability of the ocular motor structures within the pons. This combination of clinical findings, termed the 8-1/2 syndrome (cranial nerve 7 + 1-1/2), allows precise localization, and magnetic resonance angiography appears to be the imaging study of choice.
authors.affiliation: Unit for Neuro-Visual Disorders, Michigan State University College of Osteopathic Medicine, East Lansing 48824-1313, USA.
authors.forename: E
authors.initials: E
authors.lastname: Eggenberger
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D001488:Basilar Artery / Q000473:pathology*; D002561:Cerebrovascular Disorders / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D003389:Cranial Nerve Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D004172:Diplopia / Q000209:etiology; D005154:Facial Nerve / Q000473:pathology*; D005158:Facial Paralysis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D013700:Giant Cell Arteritis / Q000150:complications; D006801:Humans; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D009759:Nystagmus, Pathologic / Q000209:etiology; D009886:Ophthalmoplegia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D013577:Syndrome
chemical_list: D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors; D011241:Prednisone