title: Aspiration cytology of tubular adenomas of the breast. An analysis of eight cases.
abstract: OBJECTIVE
  To analyze fine needle aspirates from tubular adenomas of the breast and elucidate cytologic features unique to these tumors.
  
  
  METHODS
  Fine needle aspiration (FNA) cytology smears from eight tubular adenomas were reviewed, with special attention given to architectural features and individual cell characteristics. Smears were then compared with those from 25 fibroadenomas and 2 tubular carcinomas for analyzing the distinguishing features.
  
  
  RESULTS
  Aspirates from tubular adenomas revealed cells arranged as small, three-dimensional balls or clusters, tubules of different shapes and less frequently as closely approximated acini. Cells were uniform, with pale cytoplasm, which showed magenta granules in the Giemsa smears from two tumors. Straight tubules, closely approximated acini and intracytoplasmic granules were not seen in aspirates from fibroadenomas. The tubules in tubular adenomas always showed myoepithelial cells and were more open than the angulated tubules of tubular carcinoma.
  
  
  CONCLUSIONS
  Tubular adenomas on FNA cytology specifically show cells arranged as small, three-dimensional balls, tubules or closely approximated acini. Cells are uniform and sometimes show intracytoplasmic granules in Giemsa-stained smears.
authors.affiliation: Department of Pathology, T.N. Medical College, Bombay Central, India.
authors.forename: T M
authors.initials: TM
authors.lastname: Shet
authors.forename: J D
authors.initials: JD
authors.lastname: Rege
mesh_terms: D000236:Adenoma / Q000175:diagnosis / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D001707:Biopsy, Needle; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology*; D003594:Cytoplasmic Granules / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000175:diagnosis; D006801:Humans; D012189:Retrospective Studies