[The effect of trental and thiotriazoline on tissue blood flow, oxygen tension and vascular reactivity in the pancreas in acute experimental pancreatitis].
It was established while experiments on dogs that in an acute pancreatitis the vessels reactivity is changing, the tissue blood flow and oxygen pressure (pO2) are lowering in pancreatic tissue. Infusion of trental and thiotriazolinum didn't impede the tissue blood flow lowering but reduced significantly the oxygen consumption by pancreatic tissue.
Fomochkin
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II
D000208:Acute Disease; D000818:Animals; D004195:Disease Models, Animal; D004285:Dogs; D004353:Drug Evaluation, Preclinical; D006439:Hemodynamics / Q000187:drug effects*; D010101:Oxygen Consumption / Q000187:drug effects*; D010179:Pancreas / Q000098:blood supply / Q000187:drug effects* / Q000378:metabolism; D010195:Pancreatitis / Q000188:drug therapy* / Q000503:physiopathology; D010431:Pentoxifylline / Q000494:pharmacology / Q000627:therapeutic use*; D012039:Regional Blood Flow / Q000187:drug effects; D014230:Triazoles / Q000494:pharmacology / Q000627:therapeutic use*; D014665:Vasodilator Agents / Q000494:pharmacology / Q000627:therapeutic use
D014230:Triazoles; D014665:Vasodilator Agents; D010431:Pentoxifylline
Vliianie trentala i tiotriazolina na tkanevyĭ krovotok, napriazhenie kisloroda i reaktivnost' sosudov v podzheludochnoĭ zheleze pri ostrom éksperimental'nom pankreatite.