Clostridium septicum infection and hemolytic uremic syndrome.
Five cases of Clostridium septicum infection secondary to Escherichia coli O157-induced hemolytic uremic syndrome have been reported. We report on three cases (one of which is included in the above five) of dual Cl. septicum and E. coil infection; all three patients were exposed to farm animals. A common zoonotic source for Cl. septicum and E. coli O157 infections should be considered. Patients with hemolytic uremic syndrome should be treated aggressively and monitored closely for Cl. septicum superinfection.
Barnham
M
M
Harrogate General Hospital, United Kingdom.
Weightman
N
N
D000368:Aged; D000818:Animals; D000829:Animals, Domestic; D002675:Child, Preschool; D003013:Clostridium / Q000302:isolation & purification; D003015:Clostridium Infections / Q000209:etiology* / Q000382:microbiology; D004927:Escherichia coli Infections / Q000150:complications* / Q000382:microbiology; D019453:Escherichia coli O157 / Q000302:isolation & purification; D006463:Hemolytic-Uremic Syndrome / Q000150:complications* / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015163:Superinfection / Q000209:etiology*; D015047:Zoonoses