title: [Comparison between invasive tests for the diagnosis of Helicobacter pylori infections].
abstract: Helicobacter pylori is a Gram negative bacteria that colonizes gastric epithelial cells. It has been associated with several gastric disease including chronic gastritis and peptic ulcer. Helicobacter pylori infection diagnosis can be done with invasive and non-invasive methods. In invasive methods an endoscopic gastric mucosa biopsy specimen is used. In our study we compare the sensitivity, specificity, costs and applicability of four invasive diagnostic tests: culture, urease ultra-rapid test, histology (Giemsa and Hematoxilineosin stain) and fuchsin stained mucosal slides. Urease test was the easiest, fastest diagnostic test, with sensitivity of 86% and specificity of 100%, being also the cheapest test. We concluded that it should be the test of choice for Helicobacter pylori infection diagnosis.
authors.affiliation: Setor de Endoscopia Digestiva, Universidade Federal de São Paulo.
authors.forename: M
authors.initials: M
authors.lastname: Morais
authors.forename: E P
authors.initials: EP
authors.lastname: Macedo
authors.forename: M R
authors.initials: MR
authors.lastname: da Silva Júnior
authors.forename: M R
authors.initials: MR
authors.lastname: Rohr
authors.forename: M L
authors.initials: ML
authors.lastname: Ferraz
authors.forename: R R
authors.initials: RR
authors.lastname: Castro
authors.forename: E
authors.initials: E
authors.lastname: Della Libera
authors.forename: E S
authors.initials: ES
authors.lastname: Siqueira
authors.forename: C Q
authors.initials: CQ
authors.lastname: Brant
authors.forename: A P
authors.initials: AP
authors.lastname: Ferrari Junior
mesh_terms: D000328:Adult; D000368:Aged; D001706:Biopsy; D016145:Endoscopy, Digestive System; D005260:Female; D005753:Gastric Mucosa / Q000382:microbiology*; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012394:Rosaniline Dyes; D012680:Sensitivity and Specificity; D014510:Urease / Q000191:economics
chemical_list: D012394:Rosaniline Dyes; D014510:Urease
vernacular_title: Comparação entre testes invasivos para o diagnóstico da infecção pelo Helicobacter pylori.