title: [Primary pediatric tumours of the central nervous system. Anatomopathological study of 623 cases].
abstract: Tumours of central nervous system (CNS) represent the second most frequent malignancy in children under 15 years of age but are the commonest cause of death. The authors present the epidemiologic and histopathologic analysis of 623 primary tumours of CNS occurring during the period 1990 to 1996 in paediatric patients. In this period 3318 biopsies of CNS were analyzed. In this total were included 623 paediatric tumours (18 7%). The age of patients ranged from 5 months to 15 years, 325 tumours occurred in males and 298 in females. The majority affected the posterior fossa. The majority of paediatric neoplasias were of glial origin (n = 277). The most frequent tumours were: astrocytoma (27.9%), medulloblastoma (9.95%), craniopharyngioma (5.93%), ependymoma (4.97%) and glioblastoma (3.37%).
authors.affiliation: Serviço de Anatomia Pathólogica, Hospital de Clínicas, Universidade Federal do Paraná (HC/UFPR), Curitiba, Brasil.
authors.forename: L F
authors.initials: LF
authors.lastname: Torres
authors.forename: G V
authors.initials: GV
authors.lastname: Jacob
authors.forename: J S
authors.initials: JS
authors.lastname: Reis-Filho
authors.forename: L
authors.initials: L
authors.lastname: de Noronha
mesh_terms: D000293:Adolescent; D000367:Age Factors; D001254:Astrocytoma / Q000453:epidemiology / Q000473:pathology*; D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000453:epidemiology / Q000473:pathology*; D001938:Brazil / Q000453:epidemiology; D002528:Cerebellar Neoplasms / Q000453:epidemiology / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008527:Medulloblastoma / Q000453:epidemiology / Q000473:pathology; D012737:Sex Factors
vernacular_title: Tumores pediátricos primários do sistema nervoso central. Estudio anatomopatológico de 623 casos.