[Combined deficiency of thyroid stimulating hormone and growth hormone in a diabetic patient with Hashimoto thyroiditis].
We report the case of a 36-year-old female patient with insulin dependent diabetes who developed hypothyroidism of pituitary origin after giving birth. She had low levels of free T4 and TSH with no response to i.v. TRH. Antimicrosome antibodies were increased (1/25000), suggesting Hashimoto's thyroiditis. The other hormones were normal except for a low level of growth hormone and insulin growth factor 1. There were no antibodies against the pituitary. MRI of the pituitary was normal. We suspect a vascular origin for this partial pituitary deficiency.
Martin-Du Pan
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Wyss
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D000328:Adult; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000175:diagnosis*; D005260:Female; D019382:Human Growth Hormone / Q000172:deficiency*; D006801:Humans; D007018:Hypopituitarism / Q000097:blood / Q000175:diagnosis; D007037:Hypothyroidism / Q000097:blood / Q000175:diagnosis*; D007231:Infant, Newborn; D007334:Insulin-Like Growth Factor I / Q000172:deficiency; D008279:Magnetic Resonance Imaging; D010902:Pituitary Gland / Q000473:pathology; D011247:Pregnancy; D011254:Pregnancy in Diabetics / Q000097:blood / Q000175:diagnosis*; D011644:Puerperal Disorders / Q000097:blood / Q000175:diagnosis*; D013967:Thyroiditis, Autoimmune / Q000097:blood / Q000175:diagnosis*; D013972:Thyrotropin / Q000172:deficiency*
D019382:Human Growth Hormone; D007334:Insulin-Like Growth Factor I; D013972:Thyrotropin
Déficits combinés en thyréostimuline et en hormone de croissance chez une diabétique atteinte de thyroïdite de Hashimoto.