Electrical connection of native and transplanted sinus nodes via atrial to atrial pacing improves exercise performance after cardiac transplantation.
Chronotropic incompetence limits exercise performance in cardiac transplant patients. Electrical linkage of the innervated native sinus node and the denervated donor atrium or direct donor atrium pacing improves exercise performance in patients early after transplant.
Beniaminovitz
A
A
Division of Circulatory Physiology, Columbia Presbyterian Medical Center, New York, New York 10032, USA.
Coromilas
J
J
Oz
M
M
Galantowicz
M
M
Donchez
L
L
Mancini
D
D
D000328:Adult; D000368:Aged; D002304:Cardiac Pacing, Artificial; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006325:Heart Atria / Q000503:physiopathology*; D006339:Heart Rate / Q000502:physiology*; D016027:Heart Transplantation / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000503:physiopathology*; D012815:Signal Processing, Computer-Assisted; D012849:Sinoatrial Node / Q000503:physiopathology / Q000637:transplantation*; D016896:Treatment Outcome