Effect of temperature on motor responses in organophosphate intoxication.
We studied the effect of temperature on median motor responses in a 41-year-old man with organophosphate intoxication. At 32 degrees C, a normal amplitude compound motor action potential (CMAP) and a smaller spontaneous repetitive discharge (SRMAP) were present. With warming to 39 degrees C, the CMAP amplitude decreased 20%, while the SRMAP amplitude decreased 33%. With cooling to 14 degrees C, the CMAP amplitude decreased 9%, while the SRMAP became unobtainable. Possible mechanisms for these findings are discussed.
Rutchik
J S
JS
Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA.
Rutkove
S B
SB
D000328:Adult; D003080:Cold Temperature; D019054:Evoked Potentials, Motor / Q000502:physiology*; D006358:Hot Temperature; D006801:Humans; D007306:Insecticides / Q000633:toxicity*; D008297:Male; D008475:Median Nerve / Q000502:physiology; D009046:Motor Neurons / Q000502:physiology; D018482:Muscle, Skeletal / Q000294:innervation / Q000502:physiology; D009943:Organophosphorus Compounds; D011115:Polyneuropathies / Q000139:chemically induced* / Q000503:physiopathology
D007306:Insecticides; D009943:Organophosphorus Compounds