[The role of cell interaction in initiation of radiation-induced death of thymocytes and apoptosis].
The experimental evidence of crucial importance of cell interactions for initiation of radiation-induced thymocyte death was obtained. It has been proposed that ionizing radiation, in contrast to many other cytotoxic agents, initiates thymocyte death simultaneously by different independent pathways, affecting all cellular components. The concept of apoptosis as "programmed cell death" has been critically discussed.
Eĭdus
L Kh
LKh
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Russia.
D000818:Animals; D017209:Apoptosis / Q000502:physiology / Q000528:radiation effects*; D002450:Cell Communication / Q000528:radiation effects*; D016923:Cell Death / Q000502:physiology / Q000528:radiation effects; D008214:Lymphocytes / Q000378:metabolism / Q000528:radiation effects*; D013950:Thymus Gland / Q000166:cytology / Q000528:radiation effects*
Rol' mezhkletochnogo vzaimodeĭstviia v initsiatsii radiatsionnoĭ gibeli timotsitov i problema apoptoza.