Evidence for person-to-person transmission of Candida lusitaniae in a neonatal intensive-care unit.
Candida lusitaniae is an increasingly important nosocomial bloodstream pathogen. Epidemiological investigation and molecular typing techniques identified three neonates infected with identical strains of C lusitaniae that were distinguished readily from epidemiologically unrelated strains from other locations in the hospital. The results of this study provide evidence for nosocomial transmission of C lusitaniae in a neonatal intensive-care unit and suggest that these infants are at increased risk for infection with this agent.
Fowler
S L
SL
Department of Pediatrics, Medical University of South Carolina, Charleston 29425-3312, USA. fowlers1@musc.edu
Rhoton
B
B
Springer
S C
SC
Messer
S A
SA
Hollis
R J
RJ
Pfaller
M A
MA
D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D002175:Candida / Q000187:drug effects / Q000235:genetics*; D002177:Candidiasis / Q000188:drug therapy / Q000453:epidemiology / Q000635:transmission*; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology / Q000635:transmission*; D004352:Drug Resistance, Microbial; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal; D008826:Microbial Sensitivity Tests; D017720:Molecular Epidemiology
D000935:Antifungal Agents; D000666:Amphotericin B; D015725:Fluconazole