[Influence of various microbial contents in drinking water on cellular composition of lymphoid plaque in the small intestine of the rat].
Morphological investigations of rats after extended period of drinking water with varying amounts of conventionally pathogenic microflora revealed changes in the cellular composition of different morphological/functional sections of lymphoid plaques in the small intestine which depended on concentrations of microorganisms. Comparing with the control, sites of lymphoid node reproduction were significantly richer in the relative number of plaques and large lymphocytes when water contained 1,000 microbial bodies in 1 cm3. Concentrations of microorganisms higher, the parameters tended down to referential levels. Rise in water concentrations of microorganisms was associated with a decrease in the relative number of small lymphocytes, i.e. main members of the cell in lymphoid nodule mantle with the reproduction site, and an increase in the number of plasmatic cells and macrophages in the diffuse lymphoid tissue. Lymphoid nodes lacking the reproduction sites were observed in the control and in the group of animals who drank minimum microbes (100 cells in 1 cm3). These nodules were viewed again in the rats who had drunk maximum antigens (1 000,000 cells in 1 cm3). These changes point to proliferation and differentiation of lymphoid cells driven by water microorganisms, and inhibition of these processes by water concentrations of conventionally pathogenic microflora above 1,000 microbial bodies in 1 cm3.
Maslenikov
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D000818:Animals; D004755:Enterobacteriaceae / Q000302:isolation & purification*; D007421:Intestine, Small / Q000382:microbiology* / Q000473:pathology*; D008214:Lymphocytes / Q000382:microbiology*; D008221:Lymphoid Tissue / Q000382:microbiology*; D008264:Macrophages / Q000382:microbiology*; D051381:Rats; D014871:Water Microbiology
Vliianie razlichnogo soderzhaniia mikroorganizmov v pit'evoĭ vode na kletochnyĭ sostav limfoidnykh bliashek tonkoĭ kishki krys.