[Current concepts of digestion and absorption of carbohydrates].
The aim of this paper is to review recent aspects of digestion and absorption of carbohydrates that are the main source of energy in human diets. Recent researches have found that starch is not largely hydrolysed and absorbed in the small bowel but one part of it is resistant to digestion. Several food factors may be responsible for digestion and absorption velocity and totality of carbohydrates. Therefore, carbohydrate classification must be based not only on molecular size to express the real carbohydrates utilization as an energy source by humans. In agreement with molecular size of carbohydrate, its classification can be: a) monosaccharides; b) disaccharides; c) oligosaccharides; d) polysaccharides. In agreement with carbohydrate digestibility or availability, its classification can be: a) digestible carbohydrates; b) undigestable carbohydrates (NSP). Carbohydrate digestibility can be altered by several factors like: Intrinsic factors: a) physical structure; b) molecular physical distribution; c) physical state of food; d) food antinutrients. Extrinsics factors: a) chewing; b) transit time of food; c) amount of starch present; d) diet antinutrients. Under influence of this factors, process of digestion happen by enzymatic activity a long the gastrointestinal tract. Salivary and pancreatic amylase; glycosidases of the duodenal enterocyte brush border (lactase, sacarase and maltase), whose activity happen by close interaction of digestive breakdown with transport. The summarized pathways of the absorptive process: 1. movement from the bulk phase of the lumenal or mucosal fluid to enterocyte surface; 2. movement across the brush border membrane through specific transporters: a) SGLT1; b) GLUT 5; c) passive diffusion. 3. movement across the basolateral membrane by the GLUT 2.
Luz
S dos S
Sdos S
Depto. de Alimentos e Nutrição Experimental, Faculdade de Ciências Farmacêuticas, São Paulo.
de Campos
P L
PL
Ribeiro
S M
SM
Tirapegui
J
J
D050260:Carbohydrate Metabolism; D002241:Carbohydrates / Q000145:classification; D004040:Dietary Carbohydrates / Q000378:metabolism; D004063:Digestion; D006801:Humans; D007408:Intestinal Absorption
D002241:Carbohydrates; D004040:Dietary Carbohydrates
Aspectos atuais da digestão e absorção de carboidratos.