title: The influence of somatostatin on postoperative outcome after elective pancreatic surgery.
abstract: A series of 34 patients with pancreatic resections was evaluated with respect to the occurrence of local and general complications. Two groups were compared, depending on whether or not treatment with somatostatin was instituted. Postoperative morbidity and mortality were less frequent when somatostatin was given (resp. 50.0 and 5.5%) than when it was omitted (resp. 68.7 and 31.2%). Less complications were observed after resections performed for chronic pancreatitis than for pancreatic cancer in the non somatostatin-treated group. It is concluded that somatostatin treatment may be beneficial in preventing complications after elective pancreatic surgery.
authors.affiliation: Department of Surgery, Academic Surgical Centre Stuivenberg, Antwerpen, Belgium.
authors.forename: R
authors.initials: R
authors.lastname: Van Hee
authors.forename: I
authors.initials: I
authors.lastname: De Laet
authors.forename: R
authors.initials: R
authors.lastname: Salgado
authors.forename: D
authors.initials: D
authors.lastname: Ysebaert
mesh_terms: D000328:Adult; D000368:Aged; D017558:Elective Surgical Procedures; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010180:Pancreatectomy; D011183:Postoperative Complications / Q000517:prevention & control; D013004:Somatostatin / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D013004:Somatostatin