Disseminated Fusarium solani infection with endocarditis in a lung transplant recipient.
Eleven days after double lung transplantation for cystic fibrosis, an 18-year-old patient developed a disseminated Fusarium solani infection with tricuspid valve endocarditis. This infection occurred under fluconazole and immunosuppressive therapy with cyclosporin, prednisone and azathioprine, with a normal leucocyte count. Liposomal amphotericin B allowed blood culture negativation. The patient died from a bacterial septic shock.
Guinvarc'h
A
A
Department of Cardiovascular Surgery, Broussais Hospital, Paris, France.
Guilbert
L
L
Marmorat-Khuong
A
A
Lavarde
V
V
Chevalier
P
P
Amrein
C
C
Guillemain
R
R
Berrebi
A
A
D000293:Adolescent; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D003550:Cystic Fibrosis / Q000601:surgery; D004696:Endocarditis / Q000382:microbiology*; D005260:Female; D016469:Fungemia / Q000188:drug therapy / Q000382:microbiology*; D005670:Fusarium / Q000187:drug effects / Q000302:isolation & purification*; D006801:Humans; D016867:Immunocompromised Host; D008081:Liposomes; D016040:Lung Transplantation / Q000009:adverse effects*; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology*; D009894:Opportunistic Infections / Q000188:drug therapy / Q000382:microbiology*
D000935:Antifungal Agents; D008081:Liposomes; D000666:Amphotericin B