title: [Fibrinogen as independent risk factor for ischemic stroke].
abstract: We have studied fibrinogen levels (Clauss technique) in atherothrombotic ischemic stroke patients, in order to determine its role as a thrombogenic risk factor. Twenty nine patients (20 men and 9 women) between 25 and 79 years old were studied; they all have had a atherothrombotic stroke. They were classified into two groups according to the result of their carotid doppler ultrasonography: gl-without carotid flow reduction (n = 19) and g2-with carotid flow reduction (n = 10). The fibrinogen mean value was 269 mg/dl in gl and 353 mg/dl in g2. There were 47% of patients in gl and 80% of patients in g2 who presented levels > 300 mg/dl. The proportions of the groups were significantly different (p < 0.05). Considering the epidemiological value of 300 mg/dl, we conclude that the fibrinogen can be an independent risk factor for ischemic atherothrombotic stroke, specially in those whose carotid flow is reduced.
authors.affiliation: Universidade Federal de São Paulo, Disciplina de Neurologia, Brasil. Maiumi@sti.com.br
authors.forename: M M
authors.initials: MM
authors.lastname: Fukujima
authors.forename: T L
authors.initials: TL
authors.lastname: Martinez
authors.forename: L E
authors.initials: LE
authors.lastname: Pinto
authors.forename: C do R
authors.initials: Cdo R
authors.lastname: Auriemo
authors.forename: L A
authors.initials: LA
authors.lastname: de Andrade
mesh_terms: D000328:Adult; D000368:Aged; D002545:Brain Ischemia / Q000097:blood; D002561:Cerebrovascular Disorders / Q000097:blood / Q000453:epidemiology*; D005260:Female; D005340:Fibrinogen / Q000032:analysis* / Q000502:physiology; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000097:blood; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D018709:Statistics, Nonparametric
chemical_list: D005340:Fibrinogen
vernacular_title: Fibrinogênio como fator de risco independente de doença vascular cerebral.