title: Successful treatment of Grover's disease with calcipotriol.
abstract: We report the case of an 84-year-old man with clinical, histological and electron-microscopic features of a Darier-like pattern of Grover's disease. The lesions had a persistent course, with a 5-month history before diagnosis and a clinical onset 2 years after the surgical removal of a cholangiocarcinoma. A significant clinical improvement was observed after a three-week course of calcipotriol ointment applied as a monotherapy regimen. Clinical uses of topical calcipotriol in dermatological conditions are reviewed with emphasis on dyskeratotic disorders.
authors.affiliation: Department of Dermatology, Hospital de São João, Alameda Prof. Hernâni Monteiro, 4200 Porto, Portugal.
authors.forename: A V
authors.initials: AV
authors.lastname: Mota
authors.forename: T M
authors.initials: TM
authors.lastname: Correia
authors.forename: J M
authors.initials: JM
authors.lastname: Lopes
authors.forename: J M
authors.initials: JM
authors.lastname: Guimarães
mesh_terms: D000051:Acantholysis / Q000188:drug therapy* / Q000473:pathology*; D000287:Administration, Topical; D000368:Aged; D000369:Aged, 80 and over; D002117:Calcitriol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D016896:Treatment Outcome
chemical_list: D003879:Dermatologic Agents; C055085:calcipotriene; D002117:Calcitriol