Atypical cervico-facial mycobacterial infections in childhood.
We describe three patients who presented with atypical mycobacterial infection. Although antituberculous drugs are ineffective, combination treatment with clarithromycin or amikacin and ciprofloxacin (with or without cotrimoxazole) leads to eventual resolution of the lesions. The treatment of choice, however, remains complete excision of the affected area which obviates the need for prolonged chemotherapy and minimizes the scarring which may otherwise develop after conservative treatment.
Makhani
S
S
Department of Maxillofacial Surgery, Newcastle General Hospital, Newcastle upon Tyne, UK.
Postlethwaite
K R
KR
Renny
N M
NM
Kerawala
C J
CJ
Carton
A T
AT
D000465:Algorithms; D000583:Amikacin / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002939:Ciprofloxacin; D017291:Clarithromycin / Q000627:therapeutic use; D003937:Diagnosis, Differential; D004338:Drug Combinations; D005145:Face; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D008199:Lymphadenitis / Q000382:microbiology*; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000628:therapy*; D009333:Neck; D009170:Nontuberculous Mycobacteria / Q000302:isolation & purification; D012882:Skin Tests; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000627:therapeutic use
D000900:Anti-Bacterial Agents; D004338:Drug Combinations; D002939:Ciprofloxacin; D015662:Trimethoprim, Sulfamethoxazole Drug Combination; D000583:Amikacin; D017291:Clarithromycin