title: [Propofol anesthesia for craniotomy in patients who are awake].
abstract: During craniotomy, the patient's cooperation is needed during procedures in which continuous neurological examination and mapping of crucial regions close to the area to be resected area are required. We report our experience in 9 patients who underwent such procedures under intravenous propofol as the main sedating agent. This short-acting hypnotic was administered prior to and during the painful stages of the procedure. Patients were fully asleep when the skull was opened and the dural flap raised or excised. During the rest of the operation patients were lightly sedated but remained responsive and cooperative. This enabled precise intra-operative mapping of the brain and surgery-related neurological deficits were avoided. Respiratory depression or hemodynamic compromise were not encountered. All patients were comfortable during the operation and there were no additional neurological deficits after operation. We believe that propofol should be the main sedating agent used for these procedures.
authors.affiliation: Dept. of Anesthesia and Intensive Care, Chaim Sheba Medical Center, Tel Hashomer.
authors.forename: R
authors.initials: R
authors.lastname: Ben Abraham
authors.forename: N
authors.initials: N
authors.lastname: Lieberman
authors.forename: Z
authors.initials: Z
authors.lastname: Ram
authors.forename: S
authors.initials: S
authors.lastname: Klempner
authors.forename: A
authors.initials: A
authors.lastname: Perel
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000771:Anesthesia, Intravenous / Q000379:methods*; D003399:Craniotomy; D005260:Female; D006801:Humans; D006993:Hypnotics and Sedatives; D008297:Male; D008875:Middle Aged; D010146:Pain; D015742:Propofol; D014851:Wakefulness
chemical_list: D006993:Hypnotics and Sedatives; D015742:Propofol