The effect of morphology variety of EVAL membranes on the behavior of myoblasts in vitro.
Not only the surface morphology but also the surface chemistry can be changed during the fabrication of biomaterials. Therefore, the result of a biocompatibility test of one material may alter to a great extent, dependent on the fabrication process. In this paper, the in vitro interaction of myoblasts and EVAL membranes with different surface properties was investigated. It was observed that moderate contact angle and porous structure are favourable for the cell adhesion and growth. However, cell adhesion and growth were decreased on a porous structure with particulate morphology and higher contact angle.
Young
T H
TH
Center for Biomedical Engineering, College of Medicine, National Taiwan University, Taipei, Republic of China.
Yao
C H
CH
Sun
J S
JS
Lai
C P
CP
Chen
L W
LW
D000818:Animals; D001672:Biocompatible Materials / Q000494:pharmacology*; D002448:Cell Adhesion / Q000187:drug effects; D002455:Cell Division / Q000187:drug effects; D008297:Male; D008567:Membranes, Artificial; D009132:Muscles / Q000166:cytology* / Q000187:drug effects*; D011145:Polyvinyls / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D013499:Surface Properties
D001672:Biocompatible Materials; D008567:Membranes, Artificial; D011145:Polyvinyls; C020320:ethylene-vinyl alcohol copolymer