Epithelioid haemangioendothelioma of the thyroid gland: a case report and review of literature.
OBJECTIVE
This is a hitherto unreported case of an epithelioid haemangioendothelioma of the thyroid gland.


RESULTS
The patient was a 44-year-old woman who presented with a right thyroid mass. A right subtotal thyroidectomy was performed. Histologically the lesion had characteristic epithelioid and spindle cell proliferation in a background of chondromyxoid stroma. Cytoplasmic vacuolization in the epithelioid and spindle cells was present. No atypical mitotic activity or necrosis was noted. The tumour cells were positive for factor VIII-related antigen, Ulex europeus and CD 31 and were negative for cytokeratin.


CONCLUSIONS
The patient has been followed for 24 months and is free of recurrent and metastatic disease, which is supportive of a benign course in the thyroid gland.
Siddiqui
M T
MT
Department of Pathology, The University of Texas, M.D. Anderson Cancer Center, Houston, USA.
Evans
H L
HL
Ro
J Y
JY
Ayala
A G
AG
D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D018323:Hemangioendothelioma, Epithelioid / Q000737:chemistry / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D013964:Thyroid Neoplasms / Q000737:chemistry / Q000473:pathology*
D014408:Biomarkers, Tumor