title: [Histopathology of the temporal bone in adhesive otitis media].
abstract: To understand the histopathological changes of adhesive otitis media (AOM) in human, temporal bone sections processed with the celloidin-embedding technique were reviewed. In the 338 pairs of temporal bone specimens, 20 cases (26 ears) showed characteristics of AOM. The results showed that the lesions of AOM were extensive, involving all middle ear structures including tympanic muscles, round and oval windows. There were various pathological changes, in every stage of inflammation and tissue repair. According to the main pathological characteristics, histopathological changes of the 26 ears were staged as exudation, inflammatory grannlation formation, histocyte response and collegen proliferation. As the process progressed, the amount of inflammatory cells and exudate decreased with the increase of fibroblasts. Certain factors were speculated to play an important role in the process of fibrosis. The authors analysed the difficulties in the management of AOM and causes of the unsatisfactory therapeutic results. Possible measures to improve treatment results were proposed.
authors.affiliation: PLA General Hospital, Beijing.
authors.forename: D
authors.initials: D
authors.lastname: Huang
authors.forename: S
authors.initials: S
authors.lastname: Jiang
authors.forename: W
authors.initials: W
authors.lastname: Yang
mesh_terms: D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010033:Otitis Media / Q000473:pathology*; D013701:Temporal Bone / Q000473:pathology*; D000267:Tissue Adhesions