title: Exercise training in female patients with a family history of hypertension.
abstract: The purpose of this study was to determine whether there are differences in the effects of exercise training between those with a parental history of hypertension and those without such a history. A group of 39 middle-aged hypertensive women were submitted to a 4-month exercise training programme. On the basis of their family histories, 18 individuals were classified as those having a positive parental history of hypertension (group P) and 21 individuals as those without such a history (group N). Both groups participated in a supervised training programme with the intensity set at the level producing the threshold lactate concentration for 90-120 min twice a week, together with self-determined aerobic exercise three times a week. Vital age was estimated to determine the health-fitness status. At the end of the training, group N exhibited reductions in the systolic and diastolic blood pressures at rest (12.6/ 8.0 mmHg) and increases in the peak oxygen uptake [VO2peak 21.1 (SD 5.2) vs 25.2 (SD 5.7) ml x kg(-1) x min(-1)] and oxygen uptake corresponding to lactate threshold [13.7 (SD 2.4) vs 17.0 (SD 2.0) ml x kg(-1) min(-1); P < 0.05]. Group P also showed reductions in the resting blood pressures (8.9/2.9 mmHg; P < 0.05), with no change in VO2peak (P > 0.05). There were no changes in the blood lipid and haematocrit variables in either group. The vital age decreased by approximately 4 and 7 years (P < 0.05) for groups P and N, respectively. These results would indicate that exercise training is a useful, nonpharmacological tool for the treatment of essential hypertension, especially in patients with no family history of arterial hypertension.
authors.affiliation: Doctoral Programme of Health and Sport Sciences, University of Tsukuba, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Nho
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.forename: H S
authors.initials: HS
authors.lastname: Kim
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
authors.forename: T
authors.initials: T
authors.lastname: Hiyama
mesh_terms: D001794:Blood Pressure; D015444:Exercise; D005260:Female; D006339:Heart Rate; D006400:Hematocrit; D006801:Humans; D006973:Hypertension / Q000235:genetics* / Q000628:therapy; D019344:Lactic Acid / Q000097:blood; D008055:Lipids / Q000097:blood; D008875:Middle Aged; D010101:Oxygen Consumption; D010809:Physical Fitness
chemical_list: D008055:Lipids; D019344:Lactic Acid