[Concentration of copper and ceruloplasmin in serum of patients treated for epilepsy].
In 54 epileptic patients (28 females and 26 males) aged 21-48, serum copper (Cu) and ceruloplasmin (Crl) concentrations were assessed. Comparing with control group mean serum Cu and Crl concentrations were significantly increased. We suspect that antiepileptic drugs may influence the serum Cu and Crl concentrations by hepatic enzymes induction. Clinical picture of epilepsy and treatment duration does not influence serum Cu and Crl concentrations.
Motta
E
E
II Katedry i Kliniki Neurologii, Slaskiej Akademii Medycznej, Katowicach.
Miller
K
K
Ostrowska
Z
Z
D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage*; D002570:Ceruloplasmin / Q000032:analysis* / Q000187:drug effects; D003300:Copper / Q000097:blood*; D004827:Epilepsy / Q000097:blood* / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008099:Liver / Q000187:drug effects / Q000201:enzymology; D008297:Male; D008875:Middle Aged
D000927:Anticonvulsants; D003300:Copper; D002570:Ceruloplasmin
Stezenie miedzi i ceruloplazminy w surowicy u chorych leczonych z powodu padaczki.