title: Phyllodes tumour: an update of 40 cases.
abstract: This is a retrospective study of 40 cases of phyllodes tumour treated at the National University Hospital since 1985. The mean age of presentation was 37.8 years, with a range of 15 to 58 years [standard deviation (SD) 11.22 years]. Ninety per cent of the patients were premenopausal. The mean size of tumours was 52 mm, with a range of 10 to 220 mm. Preoperative diagnosis was correct in only five patients, the lesion most commonly being mistaken as a fibroadenoma. Initial surgical treatment was by simple excision in 80% of cases. Histologically, the ratio of benign, intermediate and malignant tumours was 82.5%, 12.5% and 5% respectively. Recurrences occurred in only four patients (10%), all of whom were initially treated by simple excision. The diagnosis of phyllodes tumour continues to be difficult even with newer modalities of preoperative investigations, resulting in simple excision as initial treatment of these tumours. Expectant follow-up should be continued for these patients, with wide excision of future recurrences.
authors.affiliation: Department of Surgery, National University Hospital, Singapore.
authors.forename: P T
authors.initials: PT
authors.lastname: Iau
authors.forename: T C
authors.initials: TC
authors.lastname: Lim
authors.forename: D J
authors.initials: DJ
authors.lastname: Png
authors.forename: W T
authors.initials: WT
authors.lastname: Tan
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003937:Diagnosis, Differential; D005260:Female; D018226:Fibroadenoma / Q000175:diagnosis; D005348:Fibrocystic Breast Disease / Q000175:diagnosis; D005500:Follow-Up Studies; D006801:Humans; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D003557:Phyllodes Tumor / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D017697:Premenopause; D012189:Retrospective Studies; D012509:Sarcoma / Q000175:diagnosis; D012846:Singapore