Isochromosome 7q and Wilms tumor.
Isochromosome 7q is a nonrandom cytogenetic abnormality in Wilms tumor. Two notable cases are described: (1) a case of bilateral Wilms tumor in which only the left-sided tumor contained isochromosome 7q and (2) a case of left-sided Wilms tumor in which the tumor contained isochromosome 7q, in addition to four other chromosomal abnormalities associated with Wilms tumor.
Sandoval
C
C
Department of Pediatrics, New York Medical College, Valhalla 10595, USA.
Stringel
G
G
Ozkaynak
M F
MF
Tugal
O
O
Jayabose
S
S
D002675:Child, Preschool; D002897:Chromosomes, Human, Pair 7 / Q000235:genetics*; D005260:Female; D006801:Humans; D018404:Isochromosomes / Q000235:genetics*; D007621:Karyotyping; D007680:Kidney Neoplasms / Q000235:genetics*; D008297:Male; D014178:Translocation, Genetic; D009396:Wilms Tumor / Q000235:genetics*