[Osteomalacia cured by resection of cutaneous neurinoma].
BACKGROUND
Regression of osteomalacia after exeresis of a skin tumor is unusual.


METHODS
A 62-year-old man had suffered from bone and joint symptoms for several years due to osteomalacia which was confirmed both biologically and histologically. The patient also had a plantar neurinoma. After exeresis of the tumor the biological results returned to normal levels within one week followed by regression of the clinical signs of osteomalacia.


CONCLUSIONS
The neurinoma in this patient was apparently the cause of osteomalacia, since signs of the disease disappeared after exeresis. To date, three cases of neurinoma associated with osteomalacia have been published, including a single case with skin localization. The tumor would secrete a substance which inhibits the synthesis of vitamin D and enhances phosphorus excretion.
Caille
A
A
Service de Dermatologie, Centre Hospitalier Gilles de Corbeil, Corbeil-Essonnes.
Crouzet
J
J
Mimoune
H
H
Duterque
M
M
Perrin
P
P
Verola
O
O
D005533:Foot Dermatoses / Q000150:complications* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D009442:Neurilemmoma / Q000150:complications* / Q000473:pathology / Q000601:surgery; D010018:Osteomalacia / Q000209:etiology* / Q000628:therapy; D010758:Phosphorus / Q000097:blood; D012074:Remission Induction; D012878:Skin Neoplasms / Q000150:complications* / Q000473:pathology / Q000601:surgery; D014807:Vitamin D / Q000097:blood
D014807:Vitamin D; D010758:Phosphorus
Ostéomalacie guérie par résection d'un neurinome cutané.