title: Changes in core temperature and thermoeffector thresholds in exercise-trained rats.
abstract: Spontaneous running in a running wheel has emerged as an alternative method of exercise in small animals. The present study investigated how exercise training with a running wheel affects core temperature level and thermoeffector thresholds in rats. Female rats were allowed to run freely in the wheel for 6 months. Sedentary controls did not exercise during the same period. After the exercise training period, they were loosely restrained and their threshold core temperatures for tail skin vasodilation and cold-induced thermogenesis were determined by warming or cooling the animals by use of a chronically implanted intravenous thermode. Resting and threshold core temperatures of the exercise-trained rats were higher than those of the sedentary controls. The results suggest that in rat, exercise training with a running wheel shifts threshold temperatures for heat loss and heat production to high levels, which may result in a rise in core temperature level.
authors.affiliation: Department of Physiology, School of Medicine, Kanazawa University, Kanazawa, 920-8640, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Sugimoto
authors.forename: O
authors.initials: O
authors.lastname: Shido
authors.forename: S
authors.initials: S
authors.lastname: Sakurada
authors.forename: S
authors.initials: S
authors.lastname: Ito
authors.forename: T
authors.initials: T
authors.lastname: Nagasaka
mesh_terms: D000818:Animals; D001831:Body Temperature / Q000502:physiology*; D001833:Body Temperature Regulation / Q000502:physiology*; D004056:Differential Threshold / Q000502:physiology; D005260:Female; D009043:Motor Activity / Q000502:physiology; D010805:Physical Conditioning, Animal; D051381:Rats; D017208:Rats, Wistar; D012016:Reference Values