[Percutaneous transhepatic portal vein embolization for hepatocellular carcinoma].
We report on the significance of percutaneous transhepatic portal vein embolization (PTPE) for hepatocellular carcinoma based on the results in 111 patients who underwent PTPE in our hospital. All patients tolerated the procedure without major complications, although transient elevations in serum transaminase levels were noted. Immediately after PTPE, the portal pressure increased. Portal venous flow at the main portal trunk decreased, but the flow in the nonembolized part of the liver increased. PTPE produced regenerative hypertrophy in the nonembolized part of the liver, which was mainly predicted by the volume of the embolized area and the morphological score of the hepatitis or cirrhosis. PTPE increased the safety of subsequent hepatectomy and expanded the indications for hepatectomy. PTPE is also useful as a type of multiplicative therapy for hepatocellular carcinoma.
Tanaka
H
H
Second Department of Surgery, Osaka City University Medical School, Japan.
Kinoshita
H
H
Hirohashi
K
K
Yamasaki
O
O
Kubo
S
S
Tsukamoto
T
T
Hamba
H
H
Shuto
T
T
Morimoto
Y
Y
Mikami
S
S
D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D003131:Combined Modality Therapy; D004621:Embolization, Therapeutic / Q000379:methods*; D006498:Hepatectomy; D006801:Humans; D008099:Liver / Q000503:physiopathology; D008102:Liver Circulation; D008113:Liver Neoplasms / Q000628:therapy*; D008115:Liver Regeneration; D011169:Portal Vein; D011300:Preoperative Care