Polyneural innervation in the psoas muscle of the developing rat.
Polyneural innervation was studied in the psoas muscle in developing rats from P4 till P25 and at adult age, with the combined silver-acetylcholinesterase technique. Nerve endings were counted, and end-plates were measured. These data were compared with such data in the human. The end of polyneural innervation in the rat (around P20) and in the human (around 12 weeks postterm age) in both cases coincides with a transformation in motor behavior and postural control. The rat's psoas muscle at early stages is less heavily innervated than this muscle in the human. Up to three axons per motor end-plate were counted at P4, but in the human up to five axons at 25 weeks of post menstrual age. This difference might be related to the lower percentage of type I muscle fibers in the rat.
Ijkema-Paassen
J
J
Medical Physiology, Groningen, The Netherlands. j.ijkema-paassen@med.rug.nl
Gramsbergen
A
A
D000818:Animals; D002802:Cholinesterases / Q000032:analysis; D009045:Motor Endplate / Q000737:chemistry / Q000201:enzymology; D009046:Motor Neurons / Q000737:chemistry / Q000502:physiology*; D024510:Muscle Development; D018485:Muscle Fibers, Skeletal / Q000737:chemistry / Q000201:enzymology; D010525:Peripheral Nerves / Q000737:chemistry / Q000166:cytology* / Q000502:physiology; D016658:Psoas Muscles / Q000254:growth & development* / Q000294:innervation* / Q000502:physiology; D051381:Rats; D011919:Rats, Inbred Strains
D002802:Cholinesterases