Histoplasmin reaction. Comparison of a polysaccharide antigen to the filtrate antigen.
This work was planned by taking into account all the knowledge accumulated from the immunological study of paracoccidioidomycosis. It aimed at comparing a polysaccharide antigen from Histoplasma capsulatum to a classic histoplasmin with the help of intradermal tests of delayed type of hypersensitivity. Tests were applied to 115 individuals in Santo Amaro, a town in the State of São Paulo. Positive results using classic histoplasmin were obtained in 46.0% cases whereas positive results using the polysaccharide antigen at its highest concentration were obtained in 51.30% cases. The major conclusion in this investigation is that it is possible to use the polysaccharide antigen as histoplasmin instead of the filtrate antigen.
Fava S di
C
C
Medical School, Universidade de Santo Amaro, UNISA, São Paulo, Brasil.
Rivitti
E A
EA
Cucé
L C
LC
Weiss
S
S
Rigone
G
G
Fava-Netto
C
C
D000293:Adolescent; D000328:Adult; D000368:Aged; D000946:Antigens, Fungal / Q000276:immunology*; D005260:Female; D006658:Histoplasma / Q000276:immunology*; D006659:Histoplasmin / Q000276:immunology*; D006801:Humans; D006967:Hypersensitivity; D007428:Intradermal Tests; D008297:Male; D008875:Middle Aged; D010229:Paracoccidioidomycosis / Q000276:immunology; D011134:Polysaccharides / Q000276:immunology*
D000946:Antigens, Fungal; D011134:Polysaccharides; D006659:Histoplasmin