Apoptosis in feline panleukopenia virus-infected lymphocytes.
Feline panleukopenia virus (FPLV) was shown to induce apoptosis to feline lymphoid cells and to reduce the expression of interleukin-2 receptor alpha on the cells. FPLV-induced apoptosis might be a key element in the pathophysiology of atrophy of lymphoid tissues associated with feline panleukopenia caused by FPLV.
Ikeda
Y
Y
Departments of Veterinary Microbiology, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113, Japan.
Shinozuka
J
J
Miyazawa
T
T
Kurosawa
K
K
Izumiya
Y
Y
Nishimura
Y
Y
Nakamura
K
K
Cai
J
J
Fujita
K
K
Doi
K
K
Mikami
T
T
D000818:Animals; D017209:Apoptosis; D002415:Cats; D002460:Cell Line; D004285:Dogs; D028301:Feline Panleukopenia Virus / Q000502:physiology*; D008214:Lymphocytes / Q000166:cytology* / Q000821:virology*