title: Mollenines A and B: new dioxomorpholines from the ascostromata of Eupenicillium molle.
abstract: Two new dioxomorpholines (1 and 2) have been isolated from the sclerotioid ascostromata of Eupenicillium molle (NRRL 13062). Their structures were determined by analysis of NMR data. Mollenine A (1) exhibited moderate cytotoxicity and antibacterial activity, but neither compound displayed significant antiinsectan activity.
authors.affiliation: Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA.
authors.forename: H j
authors.initials: Hj
authors.lastname: Wang
authors.forename: J B
authors.initials: JB
authors.lastname: Gloer
authors.forename: D T
authors.initials: DT
authors.lastname: Wicklow
authors.forename: P F
authors.initials: PF
authors.lastname: Dowd
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001203:Ascomycota / Q000737:chemistry / Q000378:metabolism*; D007306:Insecticides / Q000633:toxicity; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D009025:Morpholines / Q000302:isolation & purification / Q000494:pharmacology; D012988:Soil Microbiology; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000900:Anti-Bacterial Agents; D007306:Insecticides; D009025:Morpholines; C113219:mollenine A; C113220:mollenine B