title: Comparative effects of malononitriloamide analogs of leflunomide on whole blood lymphocyte stimulation in humans, rhesus macaques, cats, dogs, and rats.
authors.affiliation: Comparative Transplantation Laboratory, School of Veterinary Medicine, University of California, Davis 95616-8745, USA.
authors.forename: C R
authors.initials: CR
authors.lastname: Gregory
authors.forename: H T
authors.initials: HT
authors.lastname: Silva
authors.forename: J D
authors.initials: JD
authors.lastname: Patz
authors.forename: R E
authors.initials: RE
authors.lastname: Morris
mesh_terms: D000328:Adult; D000480:Alkynes; D000818:Animals; D001402:B-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D002415:Cats; D004285:Dogs; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007555:Isoxazoles / Q000494:pharmacology*; D000077339:Leflunomide; D008213:Lymphocyte Activation / Q000187:drug effects* / Q000276:immunology; D008253:Macaca mulatta; D008297:Male; D009570:Nitriles / Q000494:pharmacology*; D051381:Rats; D011917:Rats, Inbred Lew; D013045:Species Specificity; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*
chemical_list: D000480:Alkynes; D007166:Immunosuppressive Agents; D007555:Isoxazoles; D009570:Nitriles; C102911:X 910279; C115284:2-cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)-2-hepten-6-ynamide; D000077339:Leflunomide