Diphenylhydantoin-induced hepatitis: a case report.
This case report is of a 25-year old man with severe diphenylhydantoin-induced hepatitis, fever, rash and generalized lymphadenopathy. Hepatic histology and lymphocyte transformation tests strongly supported the diagnosis. He made an uneventful recovery with supportive therapy.
Gloria
L
L
Liver Unit, University Hospital of Santa Maria, Lisbon, Portugal.
Serejo
F
F
Cruz
E
E
Freitas
J
J
Costa
A
A
Ramalho
F
F
Batista
A
A
de Moura
M C
MC
D000328:Adult; D000927:Anticonvulsants / Q000009:adverse effects* / Q000627:therapeutic use; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D003875:Drug Eruptions / Q000209:etiology; D006801:Humans; D008206:Lymphatic Diseases / Q000139:chemically induced; D008297:Male; D010672:Phenytoin / Q000009:adverse effects* / Q000627:therapeutic use; D012640:Seizures / Q000188:drug therapy; D013997:Time Factors
D000927:Anticonvulsants; D010672:Phenytoin