title: 99mTechnetium-dimercapto-succinic acid renal scan in the evaluation of potential long-term renal parenchymal damage associated with extracorporeal shock wave lithotripsy in children.
abstract: OBJECTIVE
  Extracorporeal shock wave lithotripsy (ESWL) has been reported as efficient and safe in children. Because of reports of renal parenchymal damage in adults, this study was designed to assess the effects of ESWL in pediatric kidneys evaluated before and after treatment with (99m)technetium dimercapto-succinic acid (DMSA) renal scan.
  
  
  METHODS
  A total of 15 children, 9 months to 15 years old (mean age 6.5 years), underwent ESWL treatment for urolithiasis. Evaluation imaging included plain abdominal radiography, excretory urogram and/or renal sonography. DMSA renal scan was performed 24 hours before ESWL and at least 6 months after treatment.
  
  
  RESULTS
  ESWL was performed in 1 session for 8 patients, 2 sessions for 6 and 3 sessions for 1, delivering a range of 600 to 3,000 shock waves per session. Treatment was successful in achieving stone-free status in 87% of the cases. Long-term followup (1 to 5 years) showed no blood pressure changes. On DMSA renal scan no acquired parenchymal scar was identified at least 6 months after ESWL treatment.
  
  
  CONCLUSIONS
  The efficacy of ESWL in treating pediatric urolithiasis is confirmed. Renal parenchymal trauma associated with ESWL does not appear to cause long-term lesions identifiable by DMSA renal scan.
authors.affiliation: Department of Pediatric Urology, Hôpital St. Joseph, Paris, France.
authors.forename: H B
authors.initials: HB
authors.lastname: Lottmann
authors.forename: F
authors.initials: F
authors.lastname: Archambaud
authors.forename: B
authors.initials: B
authors.lastname: Hellal
authors.forename: B M
authors.initials: BM
authors.lastname: Pageyral
authors.forename: M
authors.initials: M
authors.lastname: Cendron
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D007669:Kidney Calculi / Q000628:therapy; D007674:Kidney Diseases / Q000000981:diagnostic imaging* / Q000209:etiology*; D008096:Lithotripsy / Q000009:adverse effects*; D011446:Prospective Studies; D011866:Radioisotope Renography; D019275:Radiopharmaceuticals; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D013997:Time Factors
chemical_list: D019275:Radiopharmaceuticals; D019783:Technetium Tc 99m Dimercaptosuccinic Acid