Peritoneal dialysis is not a risk factor for primary vascular graft thrombosis after renal transplantation.
OBJECTIVE
To find out if patients undergoing peritoneal dialysis (PD) have an increased risk of primary vascular thrombosis of the renal allograft, compared with patients on hemodialysis (HD).


METHODS
Observational, retrospective cohort study.


METHODS
Tertiary care hospital, covering an approximate population of 2,000,000. Extensive use of suboptimal donors for renal transplantation.


METHODS
The study included 827 patients receiving a cadaveric renal transplantation (RTx) in our center between 1988 and 1997 (700 on HD and 127 on PD). We searched for a potential difference in the incidence of graft thrombosis, according to the pretransplant dialysis modality and taking into consideration the main reported risk factors for this complication of RTx.


RESULTS
The accumulated incidence of primary graft thrombosis was 4.7% in PD patients, and 6.1% in HD patients (NS). Arterial and venous thrombosis were also similar in both groups. Logistic regression analysis demonstrated that extremes of age of the donor, use of the right kidney, protracted cold ischemia, delayed graft function, and transplantation to a hypersensitized recipient independently predicted graft thrombosis. Peritoneal dialysis was not independently associated with the complication under study (adjusted odds ratio HD/PD = 2.5, 95% CI = 0.8-7.7).


CONCLUSIONS
Peritoneal dialysis is not associated with an increased risk of primary vascular thrombosis of the renal allograft.
Pérez Fontán
M
M
Division of Nephrology, Hospital Juan Canalejo, A Coruña, Spain.
Rodríguez-Carmona
A
A
García Falcón
T
T
Tresancos
C
C
Bouza
P
P
Valdés
F
F
D000328:Adult; D002102:Cadaver; D016022:Case-Control Studies; D015331:Cohort Studies; D005260:Female; D006085:Graft Survival; D006801:Humans; D015994:Incidence; D016030:Kidney Transplantation; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D010530:Peritoneal Dialysis; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology; D006435:Renal Dialysis; D012189:Retrospective Studies; D012307:Risk Factors; D013927:Thrombosis / Q000453:epidemiology* / Q000209:etiology