title: Preload and incident angle independent index of left ventricular contractility determined by continuous wave Doppler echocardiography.
abstract: Although left ventricular dP/dtmax can be accurately assessed using Doppler echocardiography, the fact that Doppler-derived dP/dtmax depends both on preload and Doppler incident angle limits its clinical value. We investigated the clinical usefulness of Doppler-derived (dP/dtmax)/IP (IP, isovolumic pressure), which is known to be relatively insensitive to preload and theoretically independent of the incident angle in 9 subjects. We conclude that Doppler-derived (dP/dtmax)/IP is relatively insensitive to both the incident angle and preload. In addition to its noninvasiveness, these unique features makes it very attractive as a clinical index of ventricular contractility.
authors.affiliation: The Cardiology Division of Medicine, National Cardiovascular Center, Suita, Osaka, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Nakatani
authors.forename: T
authors.initials: T
authors.lastname: Imanishi
authors.forename: I
authors.initials: I
authors.lastname: Nakasone
authors.forename: K
authors.initials: K
authors.lastname: Sunagawa
authors.forename: K
authors.initials: K
authors.lastname: Miyatake
mesh_terms: D015150:Echocardiography, Doppler; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D007866:Leg / Q000098:blood supply; D008297:Male; D008875:Middle Aged; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging*; D011187:Posture; D013599:Systole; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging*