title: Chromosome abnormalities in peripheral blood lymphocytes from Cebus apella (Cebidae, Platyrrhini) after X-ray irradiation.
abstract: In this paper, we describe the results of a qualitative and quantitative study of chromosomal reorganizations observed in X-irradiated (1Gy and 2Gy) and cultured lymphocytes from Cebus apella. A total of 646 breakpoints have been detected, identified and localized in the ideogram of the species. The breakpoint distribution along chromosomes, p and q arms, and bands is not random. Chromosomes #11, #12 and chromosome arms 1p, 12p, 13p, 15p, 11q, and 12q are significantly more affected than expected, while chromosome #19 and chromosome arm 19q are less affected. Terminal regions of chromosome arms accumulate a higher number of breakpoints than the rest of the chromosome (37.82%). A high percentage (93.66%) of breakpoints is found in G negative bands.
authors.affiliation: Departament de Biologia Cellular i Fisiologia, Universitat Autònoma de Barcelona, E-08193 Bellaterra, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Borrell
authors.forename: M
authors.initials: M
authors.lastname: Ponsà
authors.forename: J
authors.initials: J
authors.lastname: Egozcue
authors.forename: A
authors.initials: A
authors.lastname: Rubio
authors.forename: M
authors.initials: M
authors.lastname: Garcia
mesh_terms: D000818:Animals; D002428:Cebus; D002478:Cells, Cultured; D002869:Chromosome Aberrations; D025063:Chromosome Disorders; D002874:Chromosome Mapping; D004307:Dose-Response Relationship, Radiation; D005260:Female; D007621:Karyotyping; D008214:Lymphocytes / Q000528:radiation effects*; D008297:Male; D014965:X-Rays