A case of coumarin necrosis with penile and pedal involvement.
A 57-year-old male patient with advanced adenocarcinoma of the lung, who was administered oral anticoagulant therapy because of pulmonary embolism, developed coumarin necrosis confined to the penis and feet. To our knowledge, this patient showing acral involvement is the seventh case of coumarin-induced penile necrosis reported to date.
Harmanyeri
Y
Y
Department of Dermatology-Allergy, Gülhane Military Medical Academy, Istanbul, Turkey.
Taşkapan
O
O
Doğan
B
B
Baloğlu
H
H
Başak
M
M
D000230:Adenocarcinoma / Q000150:complications; D000925:Anticoagulants / Q000009:adverse effects*; D003374:Coumarins / Q000009:adverse effects*; D005533:Foot Dermatoses / Q000139:chemically induced / Q000473:pathology; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D010409:Penile Diseases / Q000139:chemically induced / Q000473:pathology; D011655:Pulmonary Embolism / Q000188:drug therapy* / Q000209:etiology; D012871:Skin Diseases / Q000139:chemically induced* / Q000473:pathology*
D000925:Anticoagulants; D003374:Coumarins; C030123:coumarin