Triphasic waves associated with acute naproxen overdose: a case report.
Triphasic waves (TWs) can be recorded on EEG in the course of several metabolic disorders, mainly hepatic encephalopathy. A case of acute encephalopathy due to naproxen intoxication is reported, in the course of which diffuse, bilateral and symmetrical TWs were recorded. Biochemical mechanisms that might determine both a complex encephalopathy and TWs are discussed.
Bortone
E
E
Neurological Institute, University of Parma, Italy.
Bettoni
L
L
Buzio
S
S
Giorgi
C
C
Melli
G
G
Mineo
F
F
Mancia
D
D
D000140:Acidosis, Lactic / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D000328:Adult; D000641:Ammonia / Q000097:blood; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000506:poisoning*; D001928:Brain Diseases, Metabolic / Q000139:chemically induced* / Q000175:diagnosis / Q000503:physiopathology; D002540:Cerebral Cortex / Q000187:drug effects / Q000503:physiopathology; D062787:Drug Overdose / Q000175:diagnosis* / Q000503:physiopathology; D004569:Electroencephalography / Q000187:drug effects*; D005071:Evoked Potentials / Q000187:drug effects; D006801:Humans; D008297:Male; D009288:Naproxen / Q000506:poisoning*; D013406:Suicide, Attempted
D000894:Anti-Inflammatory Agents, Non-Steroidal; D009288:Naproxen; D000641:Ammonia