title: [Langerhans cell histiocytosis. Report of four cases].
abstract: Langerhans cell histiocytosis implies the proliferation and accumulation of anomalous, cytologically benign tissue macrophages in a given site. In the Hospital General y Universitario of Alicante, Spain, from 1975 to 1996 four patients presented with granulomatosis and otorhinolaryngological signs and symptoms: a 7-year-old girl with a right mastoid eosinophil granuloma, a 2-month-old boy with Letterer-Siwe syndrome whose illness started as acute mastoiditis, a 23-month-old boy who developed eosinophil granulomas of both mastoids and one ischium, and an 8-month-old girl with a right zygomatico-temporal eosinophil granuloma. The treatment and clinical course of each case is described and compared with the results of other authors.
authors.affiliation: Servicio de ORL, Hospital General, Alicante.
authors.forename: M I
authors.initials: MI
authors.lastname: Menaches
authors.forename: A
authors.initials: A
authors.lastname: Burgos
authors.forename: M
authors.initials: M
authors.lastname: Sancho
authors.forename: J R
authors.initials: JR
authors.lastname: Gras
authors.forename: P
authors.initials: P
authors.lastname: Marco
mesh_terms: D002648:Child; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007223:Infant; D008297:Male; D008416:Mastoid / Q000000981:diagnostic imaging / Q000601:surgery; D014057:Tomography, X-Ray Computed
vernacular_title: Histiocitosis de células de langerhans. A propósito de cuatro casos.