title: Hot water swallows improve symptoms and accelerate esophageal clearance in esophageal motility disorders.
abstract: Cold liquid ingestion may precipitate episodes of dysphagia and chest pain in patients with spastic esophageal motility disorders. The effect of hot liquids on esophageal symptoms, esophageal peristalsis, and clearance and any potential therapeutic benefit in such patients has not been examined. Using esophageal scintigraphy and manometry, we have investigated the effects of hot water swallows on dysphagia, chest pain, and esophageal motility and clearance in patients with esophageal motility disorders. We studied 48 men and women with intermittent dysphagia to both solids and liquids, chest pain, and/or regurgitation. All patients underwent upper endoscopy, barium swallow, and esophageal manometry using standard techniques. Esophageal scintigraphy assessed esophageal transit time (ETT) and retrograde intraesophageal movement of bolus at baseline (22 degrees C) and after hot (60 degrees C) water swallows. Esophageal manometry assessed the amplitude and duration of esophageal contractions in response to baseline and hot water swallows. Patients were followed clinically for as long as 6 months to assess symptomatic response. We found that baseline esophageal scintigraphy revealed a mean ETT of 48.5 seconds; after hot water swallow, mean ETT was 27.8 seconds (p < 0.001). The number of secondary peaks at baseline was 3.5; after hot water swallow, it was 2.1 (p < 0.001). Baseline esophageal manometry showed a mean esophageal body contraction amplitude of 188 mm Hg (mean duration, 11.8 seconds) in response to wet swallows and 125 mm Hg (mean duration, 5.7 seconds) with hot water swallows (p < 0.001). Clinically, 28 (58%) of 48 patients noted significant (>50%) improvement of their symptoms and have been ingesting hot water or other hot liquids regularly with their meals. We conclude that hot water accelerates esophageal clearance, decreases the amplitude and duration of esophageal body contractions, and improves symptoms in patients with esophageal motility disorders. Because of its safety and simplicity, it may have an important role in the management of these chronic conditions.
authors.affiliation: Division of Gastroenterology, Veterans Affairs Health Care System, Palo Alto, California 94304, USA.
authors.forename: G
authors.initials: G
authors.lastname: Triadafilopoulos
authors.forename: H P
authors.initials: HP
authors.lastname: Tsang
authors.forename: G M
authors.initials: GM
authors.lastname: Segall
mesh_terms: D003679:Deglutition / Q000502:physiology; D004327:Drinking Behavior; D015154:Esophageal Motility Disorders / Q000175:diagnosis / Q000517:prevention & control*; D004945:Esophagoscopy; D004947:Esophagus / Q000503:physiopathology; D005260:Female; D006358:Hot Temperature; D006801:Humans; D008297:Male; D008365:Manometry; D008875:Middle Aged; D010528:Peristalsis; D019275:Radiopharmaceuticals; D013671:Technetium Tc 99m Sulfur Colloid; D014867:Water
chemical_list: D019275:Radiopharmaceuticals; D014867:Water; D013671:Technetium Tc 99m Sulfur Colloid