Clinical and stabilometric monitoring in a case of cerebellar atrophy with vitamin E deficiency.
The authors describe a case of early onset ataxia with cerebellar atrophy and vitamin E deficiency, treated with alpha-tocopherol supplementation and physically rehabilitated by postural biofeedback. Clinical assessments, serum vitamin E levels and postural evaluation by means of a stabilometric platform continued for about 2 years and significant clinical improvement was recorded. Our study confirms that combined physical therapy and vitamin E supplementation may result in improvement of cerebellar function. Motor improvement is directly related to vitamin E serum levels, providing further confirmation that normal vitamin E levels are crucial for proper brain functions.
Battisti
C
C
Institute of Neurological Sciences, Unit of Neurometabolic Diseases, University of Siena, Italy.
Toffola
E D
ED
Verri
A P
AP
Serra
E
E
Dotti
M T
MT
Formichi
P
P
Federico
A
A
D000293:Adolescent; D001284:Atrophy; D001676:Biofeedback, Psychology; D002526:Cerebellar Diseases / Q000175:diagnosis* / Q000209:etiology*; D002531:Cerebellum / Q000473:pathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D026741:Physical Therapy Modalities; D011187:Posture / Q000502:physiology; D014810:Vitamin E / Q000627:therapeutic use; D014811:Vitamin E Deficiency / Q000150:complications* / Q000503:physiopathology / Q000534:rehabilitation
D014810:Vitamin E