Successful treatment of Grover's disease with calcipotriol.
We report the case of an 84-year-old man with clinical, histological and electron-microscopic features of a Darier-like pattern of Grover's disease. The lesions had a persistent course, with a 5-month history before diagnosis and a clinical onset 2 years after the surgical removal of a cholangiocarcinoma. A significant clinical improvement was observed after a three-week course of calcipotriol ointment applied as a monotherapy regimen. Clinical uses of topical calcipotriol in dermatological conditions are reviewed with emphasis on dyskeratotic disorders.
Mota
A V
AV
Department of Dermatology, Hospital de São João, Alameda Prof. Hernâni Monteiro, 4200 Porto, Portugal.
Correia
T M
TM
Lopes
J M
JM
Guimarães
J M
JM
D000051:Acantholysis / Q000188:drug therapy* / Q000473:pathology*; D000287:Administration, Topical; D000368:Aged; D000369:Aged, 80 and over; D002117:Calcitriol / Q000031:analogs & derivatives* / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D016896:Treatment Outcome
D003879:Dermatologic Agents; C055085:calcipotriene; D002117:Calcitriol