title: [Primary large cell carcinoma of the lung in the patients undergoing pulmonary resection: a comparison between pre- and post-operative diagnosis].
abstract: Between 1981 and 1995, 591 patients with primary lung cancer underwent operations. Of these, 19 patients (3.2%) was diagnosed as a large cell carcinoma pathologically. Clinicopathologically, we analyzed a discrepancy between pre- and post-operative diagnosis of these patients. This study showed as follows: 1) Accuracy of preoperative diagnosis was 73.7%; 2) No patients with primary site in right upper lobe had a correct diagnosis; 3) Accuracy of preoperation was not depending on tumor size; 4) In retrospective findings of the biopsied specimens, 'incomplete glandular differentation' caused preoperative diagnosis to adenocarcinoma, and modification of the specimens by pneumonia caused it to squamous cell carcinoma; 5) Inadequatespecimens originated from the right upper lobe or pneumonia lobe; 6) The five-survival rate was 27.3%.
authors.affiliation: Department of Surgery, National Sanatorium Nishi-Gunma Hospital, Shibukawa, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kamiyoshihara
authors.forename: T
authors.initials: T
authors.lastname: Hirai
authors.forename: O
authors.initials: O
authors.lastname: Kawashima
authors.forename: Y
authors.initials: Y
authors.lastname: Morishita
authors.forename: A
authors.initials: A
authors.lastname: Maeshima
mesh_terms: D000328:Adult; D000368:Aged; D018287:Carcinoma, Large Cell / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011013:Pneumonectomy; D011379:Prognosis; D015996:Survival Rate