title: Folliculosebaceous cystic hamartoma.
abstract: Although folliculosebaceous cystic hamartoma (FCH) is an uncommon cutaneous entity with distinct classical and variant histopathologic features, it lacks distinctive typifying clinical features. Since the original description of five cases of FCH by Kimura et al. in 1991, 12 cases have been documented. We report a further case of FCH presenting as facial lesion in a 35 year old African male. FCH comprises prominent epithelial and mesenchymal components. The epithelial component is characterised by folliculosebaceous proliferation with cyst-like infundibular dilatation, and the mesenchymal component exhibits variable fibroplasia, vascular and neural proliferation and adipocyte metaplasia. Awareness of the lesion is important to avoid confusion with other cystic or cyst-like cutaneous lesions that contain prominent epithelial folliculosebaceous and variable mesenchymal components.
authors.affiliation: Department of Anatomical Pathology, Faculty of Medicine, University of Natal, South Africa.
authors.forename: P K
authors.initials: PK
authors.lastname: Ramdial
authors.forename: V
authors.initials: V
authors.lastname: Chrystal
authors.forename: A
authors.initials: A
authors.lastname: Madaree
mesh_terms: D017667:Adipocytes / Q000473:pathology; D000328:Adult; D004439:Eccrine Glands / Q000473:pathology; D018859:Hair Follicle / Q000473:pathology; D006222:Hamartoma / Q000473:pathology*; D006801:Humans; D008297:Male; D008648:Mesoderm / Q000473:pathology; D012627:Sebaceous Glands / Q000473:pathology*; D012871:Skin Diseases / Q000473:pathology*