title: Surgical approach of an early mammalian embryo: the rabbit model.
abstract: We describe an experimental surgical model in early rabbit embryo (12.5 days of gestation). Twenty-one embryos were operated, of which 9 survived the first postoperative week and 5 had normal further growth until term. As far as we can ascertain, this is the first successful report of a surgical approach in early mammalian embryos. We think that this model may be useful for workers involved in the study of early congenital malformations.
authors.affiliation: Department of Pediatric Surgery, Hôpital Saint-Vincent de Paul, Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Beaudoin
authors.forename: L
authors.initials: L
authors.lastname: Simon
authors.forename: J
authors.initials: J
authors.lastname: Simeoni
authors.forename: P
authors.initials: P
authors.lastname: Sacquin
authors.forename: F
authors.initials: F
authors.lastname: Bargy
mesh_terms: D000818:Animals; D000013:Congenital Abnormalities; D004622:Embryo, Mammalian / Q000601:surgery*; D005314:Embryonic and Fetal Development; D005240:Feasibility Studies; D005260:Female; D005865:Gestational Age; D008954:Models, Biological; D011247:Pregnancy; D011817:Rabbits