Relation between bone mineral content and clinical, hormonal and biochemical parameters in postmenopausal women.
We studied factors related to bone mass after a natural or surgical menopause in 73 healthy women attending the menopause clinic of a university hospital. In the natural menopause group we found inverse correlations between bone mineral density (BMD) vs. menopausal duration; BMD vs. body mass index (BMI) and BMI vs. inorganic phosphate (Pi), borderline correlations between weight vs. thyroxin (T4) and weight vs. luteinising hormone (LH) and a positive correlation between androstenedione (D4A) vs. urinary calcium (Uca). In the surgical menopause group we found some negative correlations (BMD vs. menopausal duration, BMI vs. Pi; BMI vs. dehydroepiandrosterone sulphate (DS), weight vs. DS and cortisol vs. Uca) and some positive correlations (BMD vs. free testosterone (fT), BMD vs. calcium (Ca), and BMD vs. Uca). We concluded that the serum hormone levels we measured were not useful markers of current bone mineral status.
Acar
B
B
Department of Obsteterics and Gynaecology, University of Dokuz Eyll, Faculty of Medicine, Izmir, Turkey.
Uslu
T
T
Topuz
A
A
Osma
E
E
Ercal
T
T
Posaci
C
C
Erata
Y
Y
Mumcu
A
A
D000328:Adult; D015992:Body Mass Index; D001835:Body Weight / Q000502:physiology; D015519:Bone Density / Q000502:physiology*; D002979:Climacteric / Q000502:physiology*; D005260:Female; D012739:Gonadal Steroid Hormones / Q000097:blood; D006728:Hormones / Q000097:blood*; D006801:Humans; D008594:Menopause, Premature / Q000502:physiology; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000175:diagnosis / Q000503:physiopathology*; D012307:Risk Factors; D012680:Sensitivity and Specificity
D012739:Gonadal Steroid Hormones; D006728:Hormones