title: Clinical application of a flat-panel X-ray detector based on amorphous silicon technology: image quality and potential for radiation dose reduction in skeletal radiography.
abstract: OBJECTIVE
  The purpose of this study was to compare images obtained with a self-scanning, flat-panel X-ray detector based on amorphous silicon technology with conventional screen-film radiographs and to evaluate the possibility of radiation dose reduction in skeletal radiography.
  
  
  METHODS
  One hundred twenty patients were examined prospectively using a conventional screen-film system (speed, 400; detector dose, 2.5 microGy) and a prototype digital amorphous silicon detector (simulated speed, 400 and 800, n = 120; simulated speed, 1600, n = 40). The resulting 400 images were evaluated independently by six radiologists using a subjective five-point preference scale that rated overexposure, underexposure, contrast resolution, spatial resolution, and soft-tissue presentation. Image quality was ranked on a scale from 0 to 10 according to subjective criteria. Statistical significance of differences was determined using Student's t test and confidence intervals (95% confidence level).
  
  
  RESULTS
  Comparison of conventional radiographs with digital images revealed a statistically significant preference for the digital system for soft-tissue presentation (speed 400 and 800) and visualization of osteoarthrotic changes (speed 400). A small but statistically significant preference for conventional images was found with respect to contrast and spatial resolution when digital speed was 800 or 1600; and the visibility of arthrosis at digital speed 1600, osteolysis at digital speed 800 and 1600, and fractures at digital speed 1600.
  
  
  CONCLUSIONS
  The amorphous silicon-based system with a simulated speed of 400 provided images equivalent to screen-film radiographs. For clinical tasks such as routine follow-up studies, assessment of instability, or orthopedic measurements, a radiation dose reduction of up to 75% may be possible.
authors.affiliation: Department of Diagnostic Radiology, University Hospital of Regensburg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Strotzer
authors.forename: J
authors.initials: J
authors.lastname: Gmeinwieser
authors.forename: M
authors.initials: M
authors.lastname: Völk
authors.forename: R
authors.initials: R
authors.lastname: Fründ
authors.forename: J
authors.initials: J
authors.lastname: Seitz
authors.forename: C
authors.initials: C
authors.lastname: Manke
authors.forename: H
authors.initials: H
authors.lastname: Albrich
authors.forename: S
authors.initials: S
authors.lastname: Feuerbach
mesh_terms: D000368:Aged; D001847:Bone Diseases / Q000000981:diagnostic imaging; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D010003:Osteoarthritis / Q000000981:diagnostic imaging; D011446:Prospective Studies; D011829:Radiation Dosage; D011835:Radiation Protection; D011856:Radiographic Image Enhancement; D012825:Silicon; D013679:Technology, Radiologic / Q000295:instrumentation*; D014963:X-Ray Intensifying Screens
chemical_list: D012825:Silicon