Baló's concentric sclerosis in a 4-year-old Japanese infant.
We report the youngest known case with Baló's concentric sclerosis (Baló's disease), a variant of multiple sclerosis. This 4-year-old Japanese boy was diagnosed by clinical manifestations and by characteristic findings on magnetic resonance imaging (MRI). Dexamethasone was given intravenously, 3 mg twice daily for 10 days. The clinical manifestations were resolved within 2 weeks, and the MRI findings were markedly improved after 3 weeks. Following the initiation of steroid therapy, he showed remarkable clinical and physical improvement. It cannot be excluded that the clinical improvement resulted from the steroid therapy.
Murakami
Y
Y
Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume City, Japan.
Matsuishi
T
T
Shimizu
T
T
Yamashita
Y
Y
Nagamitsu
S
S
Kojima
K
K
Kato
H
H
Tabira
T
T
D001921:Brain / Q000473:pathology; D002675:Child, Preschool; D003907:Dexamethasone / Q000627:therapeutic use; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007275:Injections, Intravenous; D007564:Japan; D008279:Magnetic Resonance Imaging; D008297:Male; D016896:Treatment Outcome
D005938:Glucocorticoids; D003907:Dexamethasone