title: Results of fibrin glue application therapy in testicular hydrocele.
abstract: Nine patients, mean age 55 years, with testicular hydroceles, were treated by aspiration and two-component fibrin glue injection. One patient was treated twice. The glue contains 70-110 mg fibrinogen and 500 IU human thrombin in 0.5- and 2-ml injections, respectively (Tisseel duo quick, Immune AB). The smaller glue volume was used in 4 cases and the larger volume in 6 cases. The average volume of hydrocele fluid was 77 (range 60-120) ml. Treatment caused no pain or discomfort other than puncture of the skin and no pain-relieving medication was required afterwards. In this series there were no infections but one conservatively treated hematoma. The hydrocele of that patient disappeared. Although the hydroceles recurred in 9 cases during the mean follow-up of 3.5 months, in 2 patients the hydroceles were clinically smaller than the original one and symptoms were milder subjectively. Our findings suggest that fibrin-adhesive glue is not sufficiently effective in treatment of testicular hydroceles.
authors.affiliation: Department of Urology, Kuopio University Hospital, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Sirpa
authors.forename: A O
authors.initials: AO
authors.lastname: Martti
mesh_terms: D000368:Aged; D015718:Fibrin Tissue Adhesive / Q000008:administration & dosage*; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D008875:Middle Aged; D013733:Testicular Diseases / Q000175:diagnosis / Q000628:therapy*; D006848:Testicular Hydrocele / Q000175:diagnosis / Q000628:therapy*; D014014:Tissue Adhesives; D016896:Treatment Outcome
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives