Irritant and allergic reactions are additive, not synergistic.
Shuster
S
S
D000485:Allergens / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000209:etiology; D017453:Dermatitis, Irritant / Q000209:etiology; D004357:Drug Synergism; D006801:Humans; D007509:Irritants / Q000009:adverse effects*
D000485:Allergens; D007509:Irritants