title: Long-term fate of Plastipore in the middle ear.
abstract: Four Plastipore prostheses, removed at revision surgery 7-10 years after implantation, have been examined. The gross appearance of the prostheses was preserved. The prostheses were surrounded by a fibrous tissue capsule and showed fibrous tissue ingrowth localized in peripheral zones. Foreign-body giant cells and macrophages were detected in small numbers. Histologic evidence of breakdown of the prostheses, in the form of microdisintegration of the walls of micropores, was detected on a small scale. Compared to the massive foreign-body reactions reported in short-term studies, the tissue reaction apparently subsides with time and becomes insignificant. Strict criteria for insertion should be regarded.
authors.affiliation: Military Medical Academy, Kobba Air Hospital, Cairo, Egypt.
authors.forename: A
authors.initials: A
authors.lastname: el-Seifi
authors.forename: B
authors.initials: B
authors.lastname: Fouad
mesh_terms: D000328:Adult; D001672:Biocompatible Materials; D002648:Child; D002675:Child, Preschool; D004429:Ear Ossicles / Q000473:pathology* / Q000601:surgery*; D005549:Foreign-Body Reaction / Q000473:pathology*; D006801:Humans; D008297:Male; D009998:Ossicular Prosthesis; D019933:Ossicular Replacement; D011095:Polyethylenes; D011475:Prosthesis Failure; D013997:Time Factors
chemical_list: D001672:Biocompatible Materials; D011095:Polyethylenes