title: [Malignant syphilis in human immunodeficiency virus infection].
abstract: BACKGROUND
  The associated infection with Treponema pallidum and human immunodeficiency virus (HIV) was responsible for the return of malignant syphilis.
  
  
  METHODS
  We report a case of malignant syphilis which revealed a HIV seropositivity. The lesions were typical. Serological features were in accordance with the diagnosis. A treatment with penicillin was prescribed and there was no relapse after five years.
  
  
  CONCLUSIONS
  The diagnosis of malignant syphilis in a HIV positive patient may be difficult. The course of the disease may be serious and a prolonged treatment with high doses of penicillin is often necessary. The occurrence of the malignant syphilis in HIV positive patients is not fortuitous and seems to be related to an abnormal immunity.
authors.affiliation: Clinique Dermatologique, Hôpital Edouard Herriot, Lyon, France.
authors.forename: L
authors.initials: L
authors.lastname: Misery
authors.forename: V
authors.initials: V
authors.lastname: Besnard
authors.forename: R
authors.initials: R
authors.lastname: Badel
authors.forename: E
authors.initials: E
authors.lastname: Marneffe-Delalande
authors.forename: M
authors.initials: M
authors.lastname: Faure
authors.forename: J
authors.initials: J
authors.lastname: Thivolet
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy / Q000473:pathology*; D000328:Adult; D005148:Facial Dermatoses / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D010400:Penicillin G / Q000627:therapeutic use; D013591:Syphilis, Cutaneous / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D010400:Penicillin G
vernacular_title: Syphilis maligne au cours de l'infection par le virus de l'immunodéficience humaine.