Histopathology of the eye in diffuse neonatal hemangiomatosis.
OBJECTIVE
To report the ocular presentation and histopathology of a patient with diffuse neonatal hemangiomatosis.


METHODS
Case report. A 3.7-kg female was born at term. Multiple hemangiomas were present, and the patient died 39 days after birth.


RESULTS
Widespread cutaneous and visceral hemangiomas were present. Ophthalmic examination disclosed bilateral eyelid and conjunctival hemangiomas. The right eye had multiple iris hemangiomas, hyphema, vitreous hemorrhage, and discrete subretinal lesions. Histopathology of the right eye demonstrated hemangiomas involving the iris, ciliary body, and ciliary processes.


CONCLUSIONS
Diffuse neonatal hemangiomatosis was associated with ophthalmic findings of multiple hemangiomas involving eyelid, conjunctiva, iris, ciliary body, and ciliary processes.
Chang
C W
CW
University of British Columbia, Faculty of Medicine.
Rao
N A
NA
Stout
J T
JT
D003230:Conjunctival Neoplasms / Q000473:pathology*; D005142:Eyelid Neoplasms / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006391:Hemangioma / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D015811:Iris Neoplasms / Q000473:pathology*; D009378:Neoplasms, Multiple Primary / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*