Visual improvement during octreotide therapy in a case of episellar meningioma.
Meningiomas of the tuberculum sellae can induce compression of the optic tract. We report the case of a 54-year-old female patient affected by a suspected pituitary macroadenoma with severe visual field defects, who experienced a significant clinical and visual improvement during short-term octreotide therapy, contrasting with the lack of neuroradiological evidence for tumor shrinkage. The patient subsequently underwent transcranial surgery with a final diagnosis of meningioma. The putative mechanisms of visual improvement during octreotide therapy are discussed.
Jaffrain-Rea
M L
ML
Dipartimento di Medicina Sperimentale, Università degli Studi, L'Aquila (AQ), Italy.
Minniti
G
G
Santoro
A
A
Bastianello
S
S
Tamburrano
G
G
Gulino
A
A
Cantore
G
G
D000236:Adenoma / Q000175:diagnosis*; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D008579:Meningioma / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D008875:Middle Aged; D015282:Octreotide / Q000627:therapeutic use*; D010911:Pituitary Neoplasms / Q000175:diagnosis*; D016896:Treatment Outcome; D014786:Vision Disorders / Q000188:drug therapy* / Q000209:etiology
D018931:Antineoplastic Agents, Hormonal; D015282:Octreotide