title: Biotransformation of shiromodiol diacetate, myli-4(15)-en-9-one and myliol by Aspergillus niger.
abstract: Microbiol biotransformation of shiromodiol diacetate from Neolitsea serisea koids, and of myli-4(15)-en-9-one and myliol from the liverwort Mylia taylorii, were carried out with Aspergillus niger IFO 4407. A. niger hydroxylated the allyl position (C-2) of shiromodiol diacetate, and one of the geminal dimethyl groups of myli-4(15)-en-9-one and myliol regioselectively. The structures of these transformants were elucidated by spectral analysis and confirmed by X-ray analysis.
authors.affiliation: Department of Biochemistry, Faculty of Science, Okayama University of Science, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Hayashi
authors.forename: K
authors.initials: K
authors.lastname: Asano
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.forename: D
authors.initials: D
authors.lastname: Takaoka
authors.forename: H
authors.initials: H
authors.lastname: Nozaki
mesh_terms: D001234:Aspergillus niger / Q000378:metabolism*; D001711:Biotransformation; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry / Q000493:pharmacokinetics*; D013237:Stereoisomerism
chemical_list: D012717:Sesquiterpenes; C113439:myli-4(15)-en-9-one; C113438:shiromodiol diacetate; C113437:myliol