title: Total simultaneous repair of coarctation and intracardiac pathology in adult patients.
abstract: BACKGROUND
  Thoracic aortic coarctation accompanied by a second surgically reparable lesion is a rare combination in the adult patient. The simultaneous operative management of both lesions is desirable because of the higher morbidity and mortality that would occur with staged procedures.
  
  
  METHODS
  We describe the simultaneous operative management in three adult patients with coarctation and a second cardiac lesion. All 3 patients had intrapericardial ascending aorta-descending aorta bypass and concomitant repair of a cardiac lesion. The attendant repairs in the 3 patients, respectively, were aortic valve replacement, orthotopic heart transplantation, and coronary artery bypass grafting.
  
  
  RESULTS
  Double arterial cannulation, retrograde cardioplegia, large-bore aorto-aortic bypass grafts, and early use of alpha-agonists to stabilize systemic pressure were all key to ensuring safe conduct of the operation. Each patient had an essentially uneventful postoperative course.
  
  
  CONCLUSIONS
  Thoracic coarctation and concomitant cardiac pathology can be safely and readily managed with a single-stage approach involving cardiac repair and extraanatomic ascending aorta-descending aorta bypass grafting. A review of the English-language literature of patients managed similarly is included.
authors.affiliation: Department of Cardiothoracic Surgery, Allegheny University of the Health Sciences-Hahnemann, Philadelphia, Pennsylvania 19102-1192, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Morris
authors.forename: L E
authors.initials: LE
authors.lastname: Samuels
authors.forename: S K
authors.initials: SK
authors.lastname: Brockman
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000627:therapeutic use; D000368:Aged; D001013:Aorta, Thoracic / Q000002:abnormalities / Q000601:surgery; D001017:Aortic Coarctation / Q000601:surgery*; D001021:Aortic Valve / Q000601:surgery; D001024:Aortic Valve Stenosis / Q000601:surgery; D001794:Blood Pressure / Q000187:drug effects; D019917:Blood Vessel Prosthesis Implantation; D002303:Cardiac Output, Low / Q000601:surgery; D002404:Catheterization; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000601:surgery; D006324:Heart Arrest, Induced / Q000379:methods; D006331:Heart Diseases / Q000601:surgery*; D016027:Heart Transplantation; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D008297:Male; D008875:Middle Aged; D012449:Safety
chemical_list: D000316:Adrenergic alpha-Agonists