title: Nasal allergen challenge and immunotherapy control.
abstract: Nasal allergen challenges, despite not reproducing exactly natural allergen exposure, are a very useful method to understand the complex cellular kinetics and cellular interactions that occur in allergic rhinitis. Cell-specific soluble mediator measurements can give useful diagnosis information as well as complementary information regarding the monitoring of specific immunotherapy. In this article we present data concerning eosinophil cationic protein and tryptase measurements after nasal allergen and the influence of specific immunotherapy on nasal peak flow before and 1, 2 and 3 years after starting immunotherapy.
authors.affiliation: Clinica Universitaria de Medicina I, Faculdade de Medicina de Lisboa, Portugal.
authors.forename: A G
authors.initials: AG
authors.lastname: Palma-Carlos
authors.forename: M L
authors.initials: ML
authors.lastname: Palma-Carlos
authors.forename: M
authors.initials: M
authors.lastname: Branco-Ferreira
authors.forename: A
authors.initials: A
authors.lastname: Spinola
authors.forename: M C
authors.initials: MC
authors.lastname: Santos
authors.forename: A
authors.initials: A
authors.lastname: Lopes-Pregral
mesh_terms: D000485:Allergens / Q000008:administration & dosage / Q000276:immunology*; D001798:Blood Proteins / Q000378:metabolism; D053818:Chymases; D047091:Eosinophil Granule Proteins; D004804:Eosinophils / Q000378:metabolism; D006801:Humans; D007167:Immunotherapy; D018836:Inflammation Mediators / Q000378:metabolism; D008407:Mast Cells / Q000378:metabolism; D009297:Nasal Mucosa / Q000276:immunology; D009299:Nasal Provocation Tests; D012220:Rhinitis / Q000276:immunology* / Q000628:therapy; D012260:Ribonucleases; D012697:Serine Endopeptidases / Q000378:metabolism; D053802:Tryptases
chemical_list: D000485:Allergens; D001798:Blood Proteins; D047091:Eosinophil Granule Proteins; D018836:Inflammation Mediators; D012260:Ribonucleases; D012697:Serine Endopeptidases; C083294:chymase 2; D053818:Chymases; D053802:Tryptases