[Postural hypotension with non-neurogenic triggers in the elderly].
BACKGROUND
Orthostatic hypotension (OH) symptoms are the most frequent reason for patients to undergo an autonomic examination. The incidence of these symptoms is greater in two groups: young people with neurally mediated syncope, and adults older than 60 years, all who have normal results in the EKG and EEG test. The baroreflex afferents induce a continuous blood pressure adjustment through the heart rate variation. There are functional changes with aging which reduce this baroreflex sensitivity and therefore the accommodation to the haemodynamic requirements is frequently impaired. A number of no neurogenic triggers can be implicated in the development of OH symptoms such as electrolytic disorders, arrhythmia with low stroke volume and drugs side effects.


METHODS
To study the influence of these factors in the elderly suffering from OH, we reviewed patients older than 60 years sent to our laboratory during the last three years. In 40 out of 207 cases we found the existence of some of the above mentioned factors as possible trigger of the symptoms, since no autonomic abnormality was present. After arrhythmia correction, in two cases, and the pharmacologic agent suppression, in four more patients, symptoms disappeared and no OH was found in a second tilting test. OH is a frequent problem in the elderly and requires a careful review of the numerous causes that could contribute to develop the symptoms.


CONCLUSIONS
To take the proper therapeutic decision, a long term monitoring seems to be necessary for the main parameters: blood pressure and EKG.
Padrino
C
C
Servicio de Neurofisiología Clínica, Hospital General La Paz, Madrid, España.
García-García
D
D
Belda
V
V
Ferrer
T
T
D000368:Aged; D000375:Aging / Q000502:physiology; D000928:Antidepressive Agents / Q000009:adverse effects / Q000494:pharmacology; D001145:Arrhythmias, Cardiac / Q000150:complications; D017704:Baroreflex / Q000502:physiology*; D004232:Diuretics / Q000009:adverse effects; D004357:Drug Synergism; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D007024:Hypotension, Orthostatic / Q000139:chemically induced / Q000209:etiology* / Q000503:physiopathology; D008875:Middle Aged; D012021:Reflex, Abnormal; D012189:Retrospective Studies; D018667:Tilt-Table Test; D014665:Vasodilator Agents / Q000009:adverse effects / Q000494:pharmacology
D000928:Antidepressive Agents; D004232:Diuretics; D014665:Vasodilator Agents
Hipotensión postural con desencadenantes no neurogénicos en la vejez.