title: New ceramide from marine sponge Haliclona koremella and related compounds as antifouling substances against macroalgae.
abstract: A new ceramide N-docosanoyl-d-erythro-(2S, 3R)-16-methyl-heptadecasphing-4(E)-enine (C22 ceramide) was isolated from the marine sponge Haliclona koremella as an antifouling substance against macroalgae. The structure of this substance was elucidated by spectral means. Antifouling activity of several related compounds was also examined.
authors.affiliation: Marine Biotechnology Institute, Shimizu Laboratories, 1900 Sodeshi, Shimizu, Shizuoka 424, Japan. hatto@shimizu.mbio.co.jp
authors.forename: T
authors.initials: T
authors.lastname: Hattori
authors.forename: K
authors.initials: K
authors.lastname: Adachi
authors.forename: Y
authors.initials: Y
authors.lastname: Shizuri
mesh_terms: D000818:Animals; D002518:Ceramides / Q000302:isolation & purification* / Q000494:pharmacology; D056890:Eukaryota / Q000187:drug effects* / Q000235:genetics; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011161:Porifera / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
chemical_list: D002518:Ceramides; C113227:N-docosanoyl-16-methylheptadecasphing-4-enine