title: Bronchial carcinoid tumours in southern Saudi Arabia.
abstract: Clinical presentation, pathology, surgical management and follow-up of ten bronchial carcinoid tumour (BCT) patients are described. There were five male and five female patients with age range between 5 to 85 years (mean 39.2 +/- 21.5, SD). Pathology revealed BCT on the right side in seven and on left side in three patients. The tumour was an incidental finding in four while the other six had respiratory symptoms. Cough was present in all of the later group and hemoptysis was present in four patients. Recurrent chest infections were seen in two patients. Symptoms ranged from 1 week to 15 years. Successful surgical resection was done in nine with the longest follow-up of 80 months (mean: 23 months +/- 26.3, SD) without recurrence or metastasis. Histopathological examination of these tumours revealed classical morphological features in all but one case. Grimelius stain positivity for argyrophilia confirmed the diagnosis in all the patients in this study. Electron microscopic examination was done in patient no. 9 which showed atypical morphological features and neurosecretory granules. BCT may present like pneumonias or bronchial asthma. Although BCTs have low-grade malignancy, early diagnosis and surgical resection yield curative results almost in all cases.
authors.affiliation: Department of Surgery, College of Medicine King Saud University, Abha, Saudi Arabia.
authors.forename: T S
authors.initials: TS
authors.lastname: Malatani
authors.forename: A
authors.initials: A
authors.lastname: Batouk
authors.forename: B
authors.initials: B
authors.lastname: Teklu
authors.forename: C
authors.initials: C
authors.lastname: Irani
authors.forename: M
authors.initials: M
authors.lastname: Dewan
authors.forename: A H
authors.initials: AH
authors.lastname: Softah
authors.forename: B H
authors.initials: BH
authors.lastname: al-Ghamdi
authors.forename: I A
authors.initials: IA
authors.lastname: Grillo
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001984:Bronchial Neoplasms / Q000175:diagnosis / Q000453:epidemiology* / Q000601:surgery; D002276:Carcinoid Tumor / Q000175:diagnosis / Q000453:epidemiology* / Q000556:secondary / Q000601:surgery; D002648:Child; D002675:Child, Preschool; D003906:Developing Countries; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012529:Saudi Arabia / Q000453:epidemiology; D015996:Survival Rate