title: Patients with Hashimoto's disease treated with L-thyroxine and followed for three years.
abstract: This study investigated the effectiveness of L-thyroxine management in 32 patients (mean age 11 years and 2 months; M:F = 1:5) with Hashimoto's disease followed annually for 3 years. One (8%) of the 12 patients, euthyroid at the onset, never required treatment; of the four (33%) who began treatment immediately, two were able to stop at the 1st or 2nd follow-up, whereas two had to continue. The other seven (59%) who did not begin treatment immediately had to start at the 1st, 2nd or 3rd follow-up. The findings in this small series suggest that hormone management may prove effective to a certain extent in euthyroid Hashimoto patients, primarily as a means of prevention.
authors.affiliation: Department of Paediatrics, University of Turin, Italy.
authors.forename: G C
authors.initials: GC
authors.lastname: Mussa
authors.forename: A
authors.initials: A
authors.lastname: Corrias
authors.forename: M
authors.initials: M
authors.lastname: Mostert
authors.forename: D
authors.initials: D
authors.lastname: Pellegrino
authors.forename: L
authors.initials: L
authors.lastname: Silvestro
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D013967:Thyroiditis, Autoimmune / Q000188:drug therapy*; D013974:Thyroxine / Q000627:therapeutic use*
chemical_list: D013974:Thyroxine