title: [A case of hepatocellular carcinoma with reduction of primary tumor and disappearance of multiple lung metastasis].
abstract: A 56-year-old male had suffered from hepatocellular carcinoma treated by operation, PHoT and TAE since 1994. In December 1995, he had multiple metastases of lung in addition to recurrence of primary hepatic lesions. We discontinued treatment of TAE and decided to administer UFT (400 mg/day) orally as an outpatient. After seven months, the primary hepatic lesions were decreased in size, and metastatic lesions of lung were completely eliminated with reduction of AFP level. Generally, hepatocellular carcinoma with metastasis is refractory to treatment. However, this result suggests that UFT is one of the effective treatments for such advanced cases as having lung metastasis.
authors.affiliation: Second Dept. of Internal Medicine, Shiga University of Medical Science.
authors.forename: N
authors.initials: N
authors.lastname: Asano
authors.forename: M
authors.initials: M
authors.lastname: Fukano
authors.forename: M
authors.initials: M
authors.lastname: Kubo
authors.forename: J
authors.initials: J
authors.lastname: Sato
authors.forename: A
authors.initials: A
authors.lastname: Ito
authors.forename: T
authors.initials: T
authors.lastname: Inoue
authors.forename: T
authors.initials: T
authors.lastname: Tsujikawa
authors.forename: A
authors.initials: A
authors.lastname: Ando
authors.forename: M
authors.initials: M
authors.lastname: Sasaki
authors.forename: U
authors.initials: U
authors.lastname: Yoshioka
authors.forename: S
authors.initials: S
authors.lastname: Koyama
authors.forename: Y
authors.initials: Y
authors.lastname: Fujiyama
authors.forename: T
authors.initials: T
authors.lastname: Bamba
mesh_terms: D000284:Administration, Oral; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D014408:Biomarkers, Tumor / Q000097:blood; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy* / Q000556:secondary*; D004334:Drug Administration Schedule; D004338:Drug Combinations; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy* / Q000473:pathology; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D005641:Tegafur / Q000008:administration & dosage / Q000627:therapeutic use*; D014498:Uracil / Q000008:administration & dosage / Q000627:therapeutic use*; D000509:alpha-Fetoproteins / Q000032:analysis
chemical_list: D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D004338:Drug Combinations; C096910:UFT(R) drug; D000509:alpha-Fetoproteins; D005641:Tegafur; D014498:Uracil