title: [Community-acquired Staphylococcus aureus bacteremia in children: analysis of mortality risk factors].
abstract: Sixty episodes of community-acquired Staphylococcus aureus bacteremia (SaCB) were prospectively analyzed between January 1990 and December 1994. The mean age of the patients was 78 (1-180) months. Thirteen (55%) of the children had underlying disease, the most frequent one being acute lymphoblastic leukemia. In 83% of the episodes a primary site of infection was observed. Skin and osteoarticular foci were the most frequently encountered. Only two patients had endocarditis. Arterial hypotension was detected in 17% of the patients. Ninety two percent of S. aureus isolated were penicillin-resistant. Only two strains were methicillin-resistant. In 24 (40%) episodes where metastatic foci were detected, osteoarticular infections were predominant. Mortality due to SaCB was 20%. Multivariate analysis by logistic regression revealed that arterial hypotension (RR = 24.8; 4.77-128.9), leucopenia (RR = 10.3; 1.25-86.2) and non hemato-oncologic diseases (RR = 10.0; 1.09-92.2) correlated with high mortality rate (p = < 0.001).
authors.affiliation: Servicio de Control Epidemiológico e Infectología, Hospital de Pediatria, Buenos Aires.
authors.forename: H R
authors.initials: HR
authors.lastname: Paganini
authors.forename: F
authors.initials: F
authors.lastname: González
authors.forename: L
authors.initials: L
authors.lastname: Casimir
authors.forename: M T
authors.initials: MT
authors.lastname: Rosanova
mesh_terms: D000293:Adolescent; D016470:Bacteremia / Q000401:mortality*; D002648:Child; D002675:Child, Preschool; D017714:Community-Acquired Infections / Q000401:mortality; D006801:Humans; D007223:Infant; D011446:Prospective Studies; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000401:mortality*
vernacular_title: Bacteriemias en niños por Staphylococcus aureus adquiridas en la comunidad: análisis de los factores de riesgo de mortalidad.