Cat-scratch disease simulating Histiocytosis X.
Cat-scratch disease is a self-limited condition commonly causing a benign chronic lymphadenopathy in children. Osteolytic lesions are a rare complication, but have been previously reported. We report a case of a solitary osteolytic lesion of the skull whose clinical, radiographic and pathological features were initially interpreted as being consistent with Histiocytosis X. Subsequently, positive serological titers for Bartonella, a history of a cat-scratch antecedent to the onset of clinical symptoms and review of the original histopathology confirmed the diagnosis of cat-scratch disease. We reviewed the English language literature on osteolytic lesions associated with cat-scratch disease and compare the current case with those previously reported.
Berg
L C
LC
Department of Pathology, Gunderson Clinic, Ltd, LaCrosse, WI 45601, USA.
Norelle
A
A
Morgan
W A
WA
Washa
D M
DM
D000907:Antibodies, Bacterial / Q000032:analysis; D018416:Bartonella henselae / Q000276:immunology; D002372:Cat-Scratch Disease / Q000175:diagnosis*; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006099:Granuloma / Q000473:pathology; D006646:Histiocytosis, Langerhans-Cell / Q000175:diagnosis*; D006801:Humans; D010014:Osteolysis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000382:microbiology; D012886:Skull / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology*; D014057:Tomography, X-Ray Computed
D000907:Antibodies, Bacterial