Efficacy of moxidectin 2% oral gel against second- and third-instar Gasterophilus intestinalis De Geer.
In a trial designed to evaluate the efficacy of the recommended dosage of moxidectin 2% oral gel against the gastric stages of Gasterophilus spp., 14 ponies were selected from a herd on the basis of the inclusion criterion of the presence of Gasterophilus spp. eggs attached to their hair coats. After random allocation, the ponies were treated with 1 of 2 treatments, moxidectin 2% equine gel in a single dose at the commercial dosage of 400 microg moxidectin/kg body weight or placebo gel. The animals were necropsied 14 days posttreatment. Efficacies against second- and third-instar Gasterophilus intestinalis De Geer were 100% and 99.5%, respectively.
Scholl
P J
PJ
Fort Dodge Animal Health, Princeton, New Jersey 08543-0400, USA.
Chapman
M R
MR
French
D D
DD
Klei
T R
TR
D000284:Administration, Oral; D000704:Analysis of Variance; D000818:Animals; D000900:Anti-Bacterial Agents; D004175:Diptera; D005260:Female; D005782:Gels; D006734:Horse Diseases / Q000188:drug therapy*; D006736:Horses; D007306:Insecticides / Q000008:administration & dosage / Q000627:therapeutic use*; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy / Q000662:veterinary*; D007814:Larva; D018942:Macrolides / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D013270:Stomach / Q000469:parasitology*
D000900:Anti-Bacterial Agents; D005782:Gels; D007306:Insecticides; D018942:Macrolides; C027837:moxidectin