title: Stability of adenosine in infusion.
abstract: Using liquid chromatography the stability of adenosine in aqueous solution was investigated at five different temperatures, namely 4, 22, 37, 60 and 72 degrees C over a period of 6 months. At the three lowest temperatures, the initial concentration of the product was not altered, at the highest temperatures there was a significant decrease. From these data the shelf life (t90) at room temperature was estimated to be at least 5 years.
authors.affiliation: UZ Gasthuisberg Apotheek, Leuven, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Proot
authors.forename: A
authors.initials: A
authors.lastname: Van Schepdael
authors.forename: A A
authors.initials: AA
authors.lastname: Raymakers
authors.forename: J
authors.initials: J
authors.lastname: Hoogmartens
mesh_terms: D000241:Adenosine / Q000032:analysis / Q000737:chemistry*; D002853:Chromatography, Liquid; D004355:Drug Stability; D006863:Hydrogen-Ion Concentration; D012996:Solutions; D013696:Temperature; D013997:Time Factors
chemical_list: D012996:Solutions; D000241:Adenosine