title: Effects of dietary taurine on auditory function in full-term infants.
abstract: Three groups of neonates fed taurine supplemented infant formula, non-supplemented infant formula or breast milk, respectively, were studied from birth to 12 weeks of age. In addition to the measurement of whole blood taurine content, auditory function was monitored using auditory brainstem responses (ABRs) and transient evoked otoacoustic emissions (TEOAEs). The results showed a significant reduction in whole blood taurine concentration in the non-supplemented formula group. In addition, there was a significant drop in whole blood taurine levels in all 3 groups over the first four weeks of life. ABR wave latencies were significantly shorter in the non-supplemented group, with wave V showing the greatest reductions. Falling taurine levels after full-term birth may aid synaptic maturation/efficiency within the auditory system. TEOAE responses were significantly larger over the low to mid frequencies in the breast fed group suggesting improved middle ear function.
authors.affiliation: Hearing Services Centre City Hospital, Birmingham, England.
authors.forename: S K
authors.initials: SK
authors.lastname: Dhillon
authors.forename: W E
authors.initials: WE
authors.lastname: Davies
authors.forename: P C
authors.initials: PC
authors.lastname: Hopkins
authors.forename: S J
authors.initials: SJ
authors.lastname: Rose
mesh_terms: D001301:Audiometry, Pure-Tone; D016057:Evoked Potentials, Auditory, Brain Stem; D006801:Humans; D007223:Infant; D007225:Infant Food; D007231:Infant, Newborn; D013654:Taurine / Q000097:blood / Q000502:physiology*
chemical_list: D013654:Taurine