title: [Vasculitis affecting the kidney: analysis of 18 patients].
abstract: OBJECTIVE
  Eighteen patients who were judged to have systemic vasculitis (1990 American College of Reumathology criteria) affecting the kidney, from January 1988 to August 1996, were reviewed.
  
  
  METHODS
  We analyzed characteristics of clinical, biochemical, histopathological features, the interval between the onset of the symptoms to a diagnosis of disease, treatment and overall outcome.
  
  
  RESULTS
  The principal mode of presentation of the vasculitis is general, renal and pulmonary symptoms. The discovery of ANCA has improved the diagnostic procedure in patients with these diseases. Renal biopsy facilitates early diagnosis, prognosis and treatment. The renal lesion typically shows a segmental necrotizing glomerulonephritis and extracapillary proliferation forming crescent.
  
  
  CONCLUSIONS
  The systemic vasculitis with renal involvement carries a poor prognosis and high mortality. A variety of treatment has been employed, but their precise role in the management of these vasculitis is still being elucidated.
authors.affiliation: Servicio Nefrología, Hospital General, Castellón.
authors.forename: A
authors.initials: A
authors.lastname: Sáez-Royuela
authors.forename: J
authors.initials: J
authors.lastname: Hdez-Jaras
authors.forename: C
authors.initials: C
authors.lastname: Calvo
authors.forename: V
authors.initials: V
authors.lastname: Navarro
authors.forename: F
authors.initials: F
authors.lastname: Maduell
authors.forename: H
authors.initials: H
authors.lastname: García
authors.forename: J
authors.initials: J
authors.lastname: Vera
authors.forename: E
authors.initials: E
authors.lastname: Simon
mesh_terms: D000368:Aged; D019268:Antibodies, Antineutrophil Cytoplasmic; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D014657:Vasculitis / Q000150:complications* / Q000175:diagnosis / Q000401:mortality
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic
vernacular_title: Vasculitis sistémica con afectación renal grave: descripción de 18 casos.