Effects of GB virus-C/hepatitis G virus on hepatitis B and C viremia in multiple hepatitis virus infections.
We found that patients with dual HBV and GBV-C/HGV infection had comparable serum HBV DNA positivity and mean virus concentration compared with age-matched HBV carriers, and those with triple infection had a significantly lower HBV DNA positivity. Serum HCV RNA positivity and mean virus titer were similar between HCV carriers with or without GBV-C/HGV co-infection, and those with GBV-C/HGV co-infection seemed to have a lower serum ALT level. These data suggest that GBV-C/HGV infection exerts no significant suppression on levels of chronic hepatitis B or hepatitis C viremia.
Kao
J H
JH
Department of Internal Medicine, National Taiwan University College of Medicine, Taipei.
Chen
P J
PJ
Lai
M Y
MY
Chen
W
W
Chen
D S
DS
D000328:Adult; D004279:DNA, Viral / Q000097:blood; D005260:Female; D018067:Flaviviridae / Q000502:physiology*; D005500:Follow-Up Studies; D006514:Hepatitis B Surface Antigens / Q000097:blood; D019694:Hepatitis B, Chronic / Q000150:complications / Q000453:epidemiology / Q000821:virology*; D006526:Hepatitis C / Q000150:complications / Q000453:epidemiology / Q000821:virology*; D006525:Hepatitis, Viral, Human / Q000453:epidemiology / Q000821:virology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D015163:Superinfection / Q000821:virology; D013624:Taiwan / Q000453:epidemiology; D014766:Viremia / Q000821:virology*; D014779:Virus Replication
D004279:DNA, Viral; D006514:Hepatitis B Surface Antigens