Testicular histology in experimental uremic rats.
Testicular histology in chronic renal failure was studied using stepwise-nephrectomized and adenine-treated rats. Serum levels of urea nitrogen and creatinine were significantly higher than those in sham-operated and control rats (P < .001). However, the mean tubular diameter was not different among the 4 groups. Numbers of A-spermatogonia, preleptotene and pachytene spermatocytes, and spermatids per 100 Sertoli cells were not different among the 4 groups. It would appear that testicular histology is not influenced by chronic renal failure in rats.
Adachi
Y
Y
Department of Urology, Yamagata University School of Medicine, Japan.
Sasagawa
I
I
Tateno
T
T
Tomaru
T
T
Kubota
Y
Y
Nakada
T
T
D000818:Animals; D004195:Disease Models, Animal; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013737:Testis / Q000473:pathology*; D014511:Uremia / Q000473:pathology*