title: Regional cerebral blood flow determination using 133Xe and a standard rotating gamma-camera.
abstract: While most of the methods for quantitative regional cerebral blood flow (rCBF) determination in man requires expensive fast devices, a method is proposed using single photon emission computed tomography with a conventional rotating gamma camera and 133Xe inhalation. It is tested using a computer simulation of a cerebral exam and a simplified CBF map as a model. The results obtained show that this method is relevant and can be tested in clinical studies.
authors.affiliation: Laboratoire de Biophysique, Faculté de Médecine Lyon-Sud, Pierre-Benite, France. pbruyant@rockefeller.univ-lyonl.fr
authors.forename: P
authors.initials: P
authors.lastname: Bruyant
authors.forename: J
authors.initials: J
authors.lastname: Sau
authors.forename: J J
authors.initials: JJ
authors.lastname: Mallet
authors.forename: A
authors.initials: A
authors.lastname: Bonmartin
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology; D001921:Brain / Q000098:blood supply*; D003198:Computer Simulation; D005260:Female; D015902:Gamma Cameras; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D008297:Male; D019047:Phantoms, Imaging; D012039:Regional Blood Flow / Q000502:physiology; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation*; D014980:Xenon Radioisotopes
chemical_list: D014980:Xenon Radioisotopes