title: [The approach of cloned method in a human retinoblastoma cell line SO-Rb50].
abstract: OBJECTIVE
  In order to obtain the same characteristic tumor cells in genetical and biological aspect, the cloned human retinoblastoma cell line SO-Rb50 established in our department is reported in this paper.
  
  
  METHODS
  SO-Rb50 cells were cloned in multi-well plates.
  
  
  RESULTS
  Non-rosette Rb cells were successfully cloned while rosette Rb cells failed.
  
  
  CONCLUSIONS
  The result suggested that high differentiated Rb cells were difficult to be cloned.
authors.affiliation: Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou, China.
authors.forename: J
authors.initials: J
authors.lastname: Zheng
authors.forename: G
authors.initials: G
authors.lastname: Feng
authors.forename: Y
authors.initials: Y
authors.lastname: Li
authors.forename: Y
authors.initials: Y
authors.lastname: Yi
mesh_terms: D002999:Clone Cells; D006801:Humans; D019572:Retinal Neoplasms / Q000473:pathology*; D012175:Retinoblastoma / Q000473:pathology*; D014407:Tumor Cells, Cultured