title: Self-organizing molecular networks.
abstract: Strong diffusional mixing and short delivery times typical for micrometer and sub-micrometer reaction volumes lead to a special situation where the turnover times of individual enzyme molecules become the largest characteristic time scale of the chemical kinetics. Under these conditions, populations of cross-regulating allosteric enzymes form molecular networks that exhibit various kinds of self-organized coherent collective dynamics.
authors.affiliation: Abteilung Physikalische Chemie, Fritz-Haber-Institut der Max-Planck-Gesellschaft, Berlin, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Stange
authors.forename: D
authors.initials: D
authors.lastname: Zanette
authors.forename: A
authors.initials: A
authors.lastname: Mikhailov
authors.forename: B
authors.initials: B
authors.lastname: Hess
mesh_terms: D002468:Cell Physiological Phenomena; D004798:Enzymes / Q000737:chemistry / Q000378:metabolism*; D007700:Kinetics; D008432:Mathematical Computing; D009415:Nerve Net; D013816:Thermodynamics
chemical_list: D004798:Enzymes