title: 99mTc-MIBI uptake in a primitive leptomeningeal melanoma.
abstract: Primitive leptomeningeal melanoma is a rare and aggressive condition. The authors report on a case of primitive leptomeningeal melanoma imaged with 99mTc-Sestamibi (MIBI). There was an intense accumulation of the radiotracer in the frontal and parietal leptomeningeal regions and even after injections of gadolinium the MRI continued to reveal a cystic image of the brain. In view of the diagnosis, MRI demonstrated only limited usefulness. On the other hand, this case highlights the important role of MIBI for the imaging of malignant tumors.
authors.affiliation: Department of Nuclear Medicine, Hôpital Bellevue, CHU, 42055 Saint-Etienne Cedex, France. Claude.Soler@univ.st.etienne.fr
authors.forename: C
authors.initials: C
authors.lastname: Soler
authors.forename: P
authors.initials: P
authors.lastname: Beauchesne
authors.forename: M
authors.initials: M
authors.lastname: Moncet
authors.forename: J L
authors.initials: JL
authors.lastname: Perrot
authors.forename: J F
authors.initials: JF
authors.lastname: Mosnier
authors.forename: M J
authors.initials: MJ
authors.lastname: Fotso
authors.forename: J C
authors.initials: JC
authors.lastname: Antoine
authors.forename: J
authors.initials: J
authors.lastname: Brunon
authors.forename: F
authors.initials: F
authors.lastname: Dubois
mesh_terms: D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008545:Melanoma / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D011877:Radionuclide Imaging; D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi
chemical_list: D019275:Radiopharmaceuticals; D017256:Technetium Tc 99m Sestamibi