title: Molecular basis of beta-thalassemia in Thai Muslim patients in the the south of Thailand.
abstract: Among a sample of 29 unrelated Thai Muslim children, a total of 37 beta thalassemia genes was identified and 33 out of 37 mutations (89%) were characterized giving 6 different mutations. Four mutations [IVS-1 nt 5 (G-C), codon 19 (A-G), codons 41/42 (-CTTT) and IVS-1 nt 1 (G-T)] account for 86%. IVS-1 nt 5 (G-C) is the most common mutation found in Thai Muslim patients. Thai Muslim patients share the four most common mutations with Malays.
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Prince of Songkhla University, Thailand. lvichai@ratree,psu,ac.th
authors.forename: V
authors.initials: V
authors.lastname: Laosombat
authors.forename: C
authors.initials: C
authors.lastname: Nopparatana
authors.forename: M
authors.initials: M
authors.lastname: Wongchanchailert
authors.forename: A
authors.initials: A
authors.lastname: Wiriyasateinkul
mesh_terms: D002648:Child; D006801:Humans; D007514:Islam; D009154:Mutation; D013785:Thailand; D017086:beta-Thalassemia / Q000235:genetics*