title: [Transdermal fentanyl].
abstract: Fentanyl is a synthetic pure opioid agonist with a selective activity on mu receptors. Its high liposolubility allows a transdermal administration, using a Transdermal Therapeutic System (TTS). The clinical efficacy is widely demonstrated in the field of cancer pain control. The side effects are those observed with morphine but with less frequent constipation. The adjonction of a short acting morphine in case of acute pain is recommended.
authors.affiliation: Unité de Soins Supportifs, Soins Palliatifs et de Réhabilitation, Institut Jules Bordet, U.L.B.
authors.forename: D
authors.initials: D
authors.lastname: Lossignol
authors.forename: J
authors.initials: J
authors.lastname: Sternon
mesh_terms: D000279:Administration, Cutaneous; D000701:Analgesics, Opioid / Q000737:chemistry / Q000191:economics / Q000627:therapeutic use*; D016527:Drug Costs; D004359:Drug Therapy, Combination; D005283:Fentanyl / Q000737:chemistry / Q000191:economics / Q000627:therapeutic use*; D006801:Humans; D009020:Morphine / Q000627:therapeutic use; D017450:Receptors, Opioid, mu / Q000187:drug effects; D012995:Solubility; D013810:Therapeutic Equivalency
chemical_list: D000701:Analgesics, Opioid; D017450:Receptors, Opioid, mu; D009020:Morphine; D005283:Fentanyl
vernacular_title: Fentanyl (TTS).