[HIV protease inhibitors (new possibilities in the treatment of HIV infection and AIDS)].
In HIV/AIDS illness the reverse transcriptase and protease enzymes of human immunodeficiency virus (HIV) are currently the agents of antiretroviral therapy. Nucleoside analogues were the first group of drugs which exerted antiviral activity in humans. More recently protease inhibitors have provided new approaches in the treatment of HIV-infection and AIDS. Impressive clinical results have been obtained with combined therapies of three antiretroviral drugs, including one protease inhibitor. It is worth to mention that apart from the above, many new compounds are under development, including the vaccine against HIV.
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Szent-Györgyi Albert Orvostudományi Egyetem Szeged, Ideg- és Elmegyógyászati Klinika.
D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy* / Q000201:enzymology; D005260:Female; D015658:HIV Infections / Q000188:drug therapy* / Q000201:enzymology; D017320:HIV Protease Inhibitors / Q000627:therapeutic use*; D006801:Humans; D008297:Male
D017320:HIV Protease Inhibitors
HIV-proteáz-gátló szerek (új lehetóség a szerzett immunhiányos tünetegyüttes gyógykezelésében).