Occurrence of coagulase serotype among Staphylococcus aureus strains isolated from healthy individuals--special reference to correlation with size of protein-A gene--.
One-hundred-and-nineteen strains of Staphylococcus aureus isolated from healthy individuals for 3 years between 1991 and 1993 were subjected to an investigation on the producibility of proteins including protein A, coagulase, enterotoxins and toxic-shock syndrome toxin-1. Especially, protein A was the center of our interest. Among these strains, 69, 43, 3 and 1 strains were found to have the protein-A gene containing 5, 4, 3 and 2 IgG-binding domains, respectively. On the other hand, only one strain was devoid of the protein-A gene. There were some differences in the profile of the coagulase serotype between the group with 4 IgG-binding domains and that with 5 IgG-binding domains. Differences in the profile of toxin production were also observed between the two groups.
Seki
K
K
Department of Microbiology, The Jikei University School of Medicine, Tokyo, Japan.
Sakurada
J
J
Seong
H K
HK
Murai
M
M
Tachi
H
H
Ishii
H
H
Masuda
S
S
D003030:Coagulase / Q000378:metabolism; D004768:Enterotoxins / Q000378:metabolism; D006801:Humans; D016133:Polymerase Chain Reaction; D012703:Serotyping; D013205:Staphylococcal Protein A / Q000235:genetics* / Q000378:metabolism; D013211:Staphylococcus aureus / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism*; D014118:Toxins, Biological / Q000378:metabolism
D003030:Coagulase; D004768:Enterotoxins; D013205:Staphylococcal Protein A; D014118:Toxins, Biological