title: Influence of body composition on the bone mass of postmenopausal women.
abstract: OBJECTIVE
  To investigate the influence of body weight (BW), fat mass (FM) and lean mass (LM) on the bone mineral density (BMD) of several areas of the skeleton.
  
  
  METHODS
  Sixty one white postmenopausal women (50.1 +/- 4.8 years).
  
  
  METHODS
  Measurement of BMD by dual energy x-ray absorptiometry. The results were analyzed by linear regression and the slopes of each curve were compared.
  
  
  RESULTS
  The results showed that the correlations between BW, FM and LM to BMD were positive, whilst the correlations between age and years since menopause to BMD were negative. LM was the main factor that influence BMD in almost all areas.
  
  
  CONCLUSIONS
  FM and LM present a positive effect on BMD, although LM is the main determinant of bone mass. Moreover, higher values of LM and FM present a protective effect against the reduction of BMD combined with menopause. Therefore postmenopausal women with low BW, especially low LM, present serious risk for developing osteoporosis.
authors.affiliation: Departamento de Fisiologia e Biofísica do ICB-USP, São Paulo, Brazil.
authors.forename: M M
authors.initials: MM
authors.lastname: Marone
authors.forename: C H
authors.initials: CH
authors.lastname: Gouveia
authors.forename: S
authors.initials: S
authors.lastname: Lewin
authors.forename: S
authors.initials: S
authors.lastname: Wehba
authors.forename: L F
authors.initials: LF
authors.lastname: Malvestiti
authors.forename: A C
authors.initials: AC
authors.lastname: Bianco
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D000367:Age Factors; D001823:Body Composition; D001835:Body Weight; D015519:Bone Density; D005260:Female; D006801:Humans; D016014:Linear Models; D008875:Middle Aged; D015663:Osteoporosis, Postmenopausal / Q000209:etiology / Q000378:metabolism; D017698:Postmenopause / Q000378:metabolism*; D012307:Risk Factors