title: Analysis of testicular migration during the fetal period in humans.
abstract: OBJECTIVE
  We present an analysis concerning the testicular migration and its position correlated to body weight, crown-rump length and gestational age during the fetal period in humans without congenital abnormalities.
  
  
  METHODS
  We studied bilaterally 142 testes taken from 71 fresh human fetuses between 10 and 35 weeks after conception. The fetuses were also evaluated in regard to crown-rump length and body weight. The position of the testes was correlated to the fetal parameters.
  
  
  RESULTS
  In 37 fetuses (74 testes) at 10 to 23 weeks after conception only 7 testes (9.45%) had migrated from the abdomen and were situated in the inguinal canal, in 19 fetuses (38 testes) at 24 to 26 weeks after conception 22 testes (57.9%) had migrated from the abdomen and in 9 fetuses (18 testes) at 27 to 29 weeks after conception only 3 testes (16.7%) had not descended to the scrotum. The testes had not descended into the scrotum in any fetus weighing 990 gm. or less and with a crown-rump length of 24.5 cm. or less. On the other hand, in all fetuses weighing more than 1,220 gm. and with a crown-rump length of more than 27.5 cm. the testis was in the scrotum.
  
  
  CONCLUSIONS
  Until 23 weeks after conception the majority of testes remain in the abdomen. The more intense migration of the testes through the inguinal canal occurred between 21 and 25 weeks after conception. After 30 weeks after conception all testes were descended to the scrotum in all fetuses.
authors.affiliation: Urogenital Research Unit, State University of Rio de Janeiro, Brazil.
authors.forename: F J
authors.initials: FJ
authors.lastname: Sampaio
authors.forename: L A
authors.initials: LA
authors.lastname: Favorito
mesh_terms: D005314:Embryonic and Fetal Development; D005865:Gestational Age; D006801:Humans; D008297:Male; D013737:Testis / Q000196:embryology*