title: Effect of intra-arachnoid space perfusion on thromboxane A and prostacycline in experimental spinal cord injury.
abstract: In order to understand the relation between TXA2-PGI2 and secondary trauma and the effect of intra-arachnoid perfusion of dexamethasone and verapamil on alteration of TXA2-PGI2 following spinal cord injury, TXB2 and 6-keto-PGF alpha concentration and pathological changes in injured site 1, 2, 4, and 6 h after injury were studied using a rabbit spinal cord injury model by Allen's weight drop method.
authors.affiliation: Department of Orthopedics, Xiehe Hospital, Tongji Medical University, Wuhan.
authors.forename: Y
authors.initials: Y
authors.lastname: Tu
authors.forename: J
authors.initials: J
authors.lastname: Du
authors.forename: Z
authors.initials: Z
authors.lastname: Xia
authors.forename: L
authors.initials: L
authors.lastname: Wang
mesh_terms: D015121:6-Ketoprostaglandin F1 alpha / Q000378:metabolism*; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology; D002121:Calcium Channel Blockers / Q000494:pharmacology; D003907:Dexamethasone / Q000494:pharmacology*; D007278:Injections, Spinal; D008297:Male; D011817:Rabbits; D013119:Spinal Cord Injuries / Q000378:metabolism*; D013929:Thromboxane B2 / Q000378:metabolism*; D014700:Verapamil / Q000494:pharmacology
chemical_list: D000893:Anti-Inflammatory Agents; D002121:Calcium Channel Blockers; D013929:Thromboxane B2; D015121:6-Ketoprostaglandin F1 alpha; D003907:Dexamethasone; D014700:Verapamil