title: Surgical and chemotherapeutic treatment of alveolar echinococcosis in a dog.
abstract: Surgical removal of macroscopically detectable metacestode tissue followed by postoperative chemotherapy according to established human protocols resulted in complete clinical remission and immediate normalization of hyperglobulinemia in a dog with alveolar echinococcosis (AE). The disease is caused by the metacestode stage of the cestode, Echinococcus multilocularis. In endemic areas, AE should be included in the differential diagnosis of polycystic liver masses, especially if concomitant hyperglobulinemia is present. However, the importance of AE is not only the disease of the single dog itself but also the potential risk of infection for humans in an endemic area.
authors.affiliation: Veterinary Teaching Hospital, Department of Veterinary Internal Medicine, University of Zürich.
authors.forename: M
authors.initials: M
authors.lastname: Haller
authors.forename: P
authors.initials: P
authors.lastname: Deplazes
authors.forename: F
authors.initials: F
authors.lastname: Guscetti
authors.forename: J C
authors.initials: JC
authors.lastname: Sardinas
authors.forename: I
authors.initials: I
authors.lastname: Reichler
authors.forename: J
authors.initials: J
authors.lastname: Eckert
mesh_terms: D015766:Albendazole / Q000627:therapeutic use; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use; D000909:Antibodies, Helminth / Q000097:blood; D001707:Biopsy, Needle / Q000662:veterinary; D017024:Chemotherapy, Adjuvant / Q000662:veterinary; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000601:surgery*; D004285:Dogs; D004444:Echinococcosis, Hepatic / Q000188:drug therapy / Q000601:surgery / Q000662:veterinary*; D004446:Echinococcus / Q000276:immunology / Q000302:isolation & purification; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005243:Feces / Q000469:parasitology; D006801:Humans; D008099:Liver / Q000469:parasitology / Q000473:pathology / Q000601:surgery; D008297:Male; D011223:Praziquantel / Q000627:therapeutic use; D015047:Zoonoses
chemical_list: D000871:Anthelmintics; D000909:Antibodies, Helminth; D011223:Praziquantel; D015766:Albendazole