title: Sir Vincent Wigglesworth and the coming of age of insect development.
abstract: Sir Vincent Wigglesworth (1899-1994), a founder of the discipline of Insect Physiology, was a central figure in the emergence of the concept of postembryonic insect development as sequential polymorphism regulated by endocrine signals. At a time in mid-century when genetics and developmental physiology were severely compartmentalized, he made the conceptual linkage with the recognition that sequential polymorphism must have a genetic basis with gene activation regulated by internal signals.
authors.affiliation: Department of Zoology, University of Washington, Seattle 98195, USA. hardsnow@u.washington.edu
authors.forename: J S
authors.initials: JS
authors.lastname: Edwards
mesh_terms: D000818:Animals; D015509:Developmental Biology / Q000266:history*; D004739:England; D018507:Gene Expression Regulation, Developmental; D049673:History, 20th Century; D007313:Insecta / Q000254:growth & development*; D008967:Molecular Biology / Q000266:history*; D015533:Transcriptional Activation