title: [Clinical thinking and decision making in practice. A patient with decreased vision and a skin disorder].
abstract: In a 48-year-old man who suffered from progressive loss of vision in his left eye and metamorphopsia, pseudoxanthoma elasticum was diagnosed. Angioid streaks were observed in both eyes and the skin showed small yellow papules in a linear pattern. The right retina was twice treated by laser coagulation which resulted in temporary regression of neovascularization. Pseudoxanthoma elasticum is a genetic disorder with variable penetrance. There is no treatment. Patients should be told to refrain from contact sports and to avoid using aspirin.
authors.affiliation: Afd. Oogheelkunde, Academisch Ziekenhuis, Groningen.
authors.forename: J M
authors.initials: JM
authors.lastname: Hooymans
authors.forename: M F
authors.initials: MF
authors.lastname: Jonkman
authors.forename: W M
authors.initials: WM
authors.lastname: Molenaar
mesh_terms: D000793:Angioid Streaks / Q000175:diagnosis / Q000601:surgery; D006801:Humans; D017075:Laser Coagulation; D008297:Male; D008875:Middle Aged; D011561:Pseudoxanthoma Elasticum / Q000175:diagnosis*; D014786:Vision Disorders / Q000209:etiology
vernacular_title: Klinisch denken en beslissen in de praktijk. Een patiënt met visusdaling en huidafwijkingen.