title: The effect of sodium lauryl sulfate on recurrent aphthous ulcers: a clinical study.
abstract: This study measured the incidence of recurrent aphthous ulcers during the use of dentifrices with and without sodium lauryl sulfate (SLS). A single-blind, crossover design was used. A statistically significant reduction in recurrent aphthous ulcers was observed during 2 months' use of SLS-free dentifrice compared to 2 months' use of the SLS-containing dentifrice. These results support the results of an earlier independent study, and suggest that use of an SLS-free dentifrice should be considered for individuals suffering from recurrent aphthous ulcers.
authors.forename: L
authors.initials: L
authors.lastname: Chahine
authors.forename: N
authors.initials: N
authors.lastname: Sempson
authors.forename: C
authors.initials: C
authors.lastname: Wagoner
mesh_terms: D000328:Adult; D018592:Cross-Over Studies; D003802:Dentifrices / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016037:Single-Blind Method; D012967:Sodium Dodecyl Sulfate / Q000009:adverse effects*; D013281:Stomatitis, Aphthous / Q000139:chemically induced*; D013501:Surface-Active Agents / Q000009:adverse effects*
chemical_list: D003802:Dentifrices; D013501:Surface-Active Agents; D012967:Sodium Dodecyl Sulfate