title: An informant interview for the diagnosis of dementia and depression in older adults (IDD-GMS).
abstract: BACKGROUND
  There has been no instrument developed for the differential diagnosis of psychiatric conditions using an informant. The present study describes the development and validation of an informant interview for the diagnosis of dementia and depression in older adults (IDD-GMS). The IDD-GMs, as its name indicates, is based upon the well-established Geriatric Mental State Schedule (GMS).
  
  
  METHODS
  Thirty older adults with psychiatric illnesses were identified. An informant/career was interviewed using the IDD-GMS. Questions from the GMS were altered to reflect the informant nature of interview. Validity was compared to ICD-10 diagnoses. Interrater reliability was determined.
  
  
  RESULTS
  Using a hierarchical diagnostic system, receiver operating characteristics demonstrated one optimal cutpoint for sensitivity, > 13 for dementia and > 16 for depression, and one for specificity, > 13 for dementia and > 10 for depression.
  
  
  CONCLUSIONS
  The validity and reliability of the IDD-GMS falls within acceptable limits and indicates that the IDD-GMS can be used as a diagnostic instrument for dementia and depression. The IDD-GMS represents the first informant interview to achieve this.
authors.affiliation: Department of Psychiatry and Behavioural Sciences, University College London Medical School, UK.
authors.forename: S
authors.initials: S
authors.lastname: Lewis
authors.forename: K
authors.initials: K
authors.lastname: Hinchcliffe
authors.forename: C
authors.initials: C
authors.lastname: Katona
authors.forename: G
authors.initials: G
authors.lastname: Livingston
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017028:Caregivers / Q000523:psychology*; D003704:Dementia / Q000175:diagnosis* / Q000523:psychology; D003863:Depression / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D015577:Geriatric Assessment; D006801:Humans; D007406:Interview, Psychological / Q000379:methods / Q000592:standards*; D008131:London; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011569:Psychiatric Status Rating Scales / Q000592:standards*; D011594:Psychometrics / Q000379:methods / Q000592:standards*; D012372:ROC Curve; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012938:Social Perception