title: Nucleotide sequence of the gene encoding the RNA polymerase and the 3' non-coding region of a bovine enterovirus Japanese isolate: rapid synonymous substitutions between European and Japanese strains.
abstract: The nucleotide sequences of the genome RNA encoding the RNA polymerase and the 3' non-coding region (NCR) of bovine enterovirus (BEV) serotype I Japanese isolate, MZ468, were determined. The genetic distance between the two BEV serotype I strains, MZ468 and VG-5-27, was calculated by pairwise comparison of nucleotide sequences. The synonymous substitution rate was high (1.40 x 10(-2)/site/year), and of the same order as those of influenza virus HA, HIV-1 gag and env, and enterovirus 70 VP1 genes.
authors.affiliation: Department of Virology, Kurume University School of Medicine, Fukuoka, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Hamada
authors.forename: K
authors.initials: K
authors.lastname: Masunaga
authors.forename: Y
authors.initials: Y
authors.lastname: Ohtsu
authors.forename: H
authors.initials: H
authors.lastname: Kato
authors.forename: K
authors.initials: K
authors.lastname: Tsuji
authors.forename: H
authors.initials: H
authors.lastname: Maeda
authors.forename: M
authors.initials: M
authors.lastname: Shingu
authors.forename: T
authors.initials: T
authors.lastname: Toyoda
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002417:Cattle; D004279:DNA, Viral; D012321:DNA-Directed RNA Polymerases / Q000235:genetics*; D004770:Enterovirus / Q000145:classification / Q000201:enzymology* / Q000235:genetics / Q000302:isolation & purification; D005060:Europe; D007564:Japan; D008969:Molecular Sequence Data; D013045:Species Specificity
chemical_list: D004279:DNA, Viral; D012321:DNA-Directed RNA Polymerases