[Efficacy of ursodeoxycholic acid (UDCA) in the treatment of chronic alcoholic hepatitis].
Treatment for chronic alcoholic hepatitis with UDCA drug was performed in 76 patients. In development of this kind of hepatitis an essential role belongs to defects in the systems of lipid peroxidation and antioxidant defense. The UDCA drug produced stabilization of cell membranes, changed bile composition by effects on bile acids pool and micellar complex. Clinicomorphological remission was available in 88% of cases.
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D000328:Adult; D002756:Cholagogues and Choleretics / Q000008:administration & dosage / Q000627:therapeutic use*; D004305:Dose-Response Relationship, Drug; D005500:Follow-Up Studies; D006519:Hepatitis, Alcoholic / Q000188:drug therapy*; D006801:Humans; D008297:Male; D012074:Remission Induction; D016896:Treatment Outcome; D014580:Ursodeoxycholic Acid / Q000008:administration & dosage / Q000627:therapeutic use*
D002756:Cholagogues and Choleretics; D014580:Ursodeoxycholic Acid
Effektivnosyt' ursodezoksikholevoĭ kisloty v lechenii khronicheskogo alkogol'nogo gepatita.