Toxoplasmic retinochoroiditis: resolution without treatment of the perilesional satellite dark dots seen by indocyanine green angiography.
OBJECTIVE
Satellite dark dots (SDD) seen by indocyanine green angiography (ICGA) around the main retinochoroiditis focus are described in 75% of cases. Whether SDDs represent subclinical infectious foci or just a perilesional inflammatory reaction is not known. The purpose here was to report a case giving additional information on this question.


METHODS
We analysed the evolution of ICGA SDDs in a patient with recurrent toxoplasmic retinochoroiditis who received no antitoxoplasmic treatment because the lesion was located outside the areas where treatment is classically recommended.


RESULTS
The patient had a recurrence of retinochoroiditis on the nasal aspect of the disc about 2 disc diameters away from the disc. It was decided to observe the recurrence before introducing treatment. Diminution of SDDs occurred by 3 weeks after the initial ICGA, and complete resolution was observed on a follow-up ICG angiogram obtained 8 weeks after the initial visit.


CONCLUSIONS
Resolution of ICGA SDDs in toxoplasmic retinochoroiditis seems to occurring a similar fashion whether or not the retinochoroiditis is treated by anti-toxoplasmic drugs, indicating that SDDs probably represent a non-infectious perilesional inflammatory reaction.
Guex-Crosier
Y
Y
Department of Ophthalmology, Hôpital Jules Gonin, University of Lausanne, Switzerland.
Auer
C
C
Bernasconi
O
O
Herbort
C P
CP
D000208:Acute Disease; D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis; D002825:Chorioretinitis / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D002829:Choroid / Q000473:pathology; D004396:Coloring Agents; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D012008:Recurrence; D012075:Remission, Spontaneous; D012160:Retina / Q000473:pathology; D014122:Toxoplasma / Q000276:immunology; D014126:Toxoplasmosis, Ocular / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*
D000913:Antibodies, Protozoan; D004396:Coloring Agents; D007208:Indocyanine Green