title: Pancreatic leiomyosarcoma. Case report with immunohistochemical and flow cytometric studies.
abstract: A leiomyosarcoma originating from the pancreas of a 57-year-old man is presented. A 6x5x4 cm tumour was located in the head region, and the patient underwent surgical palliation. Immunohistochemical studies excluded an epithelial origin; a myogenic origin was suggested by strong vimentin and smooth muscle actin positivity. Flow cytometric analysis revealed an aneuploid pattern (DNA index: 1,561). The patient died with widespread metastases 7 month after the operation.
authors.affiliation: 1st Institute of Pathology and Experimental Cancer Research, Semmelweis University of Medicine, Budapest, Hungary. zalatnai@korb1.sote.hu
authors.forename: A
authors.initials: A
authors.lastname: Zalatnai
authors.forename: M
authors.initials: M
authors.lastname: Kovács
authors.forename: L
authors.initials: L
authors.lastname: Flautner
authors.forename: B
authors.initials: B
authors.lastname: Sipos
authors.forename: E
authors.initials: E
authors.lastname: Sarkady
authors.forename: J
authors.initials: J
authors.lastname: Bocsi
mesh_terms: D000199:Actins / Q000378:metabolism; D000782:Aneuploidy; D004273:DNA, Neoplasm / Q000378:metabolism; D017809:Fatal Outcome; D005434:Flow Cytometry; D006801:Humans; D007150:Immunohistochemistry; D007890:Leiomyosarcoma / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D014746:Vimentin / Q000378:metabolism
chemical_list: D000199:Actins; D004273:DNA, Neoplasm; D014746:Vimentin