[Treatment of keloid with intralesional bleomycin].
BACKGROUND
Treatment of keloids is often disappointing and sometime quite difficult to manage. In addition to unpleasant esthetic effects, treatment may also produce functional impairment due to pruritus and contraction of the scar tissue.


METHODS
We proposed a new treatment scheme using intralesional infiltrations of bleomycin.


RESULTS
We treated 31 keloids and 5 hypertrophic scars with 3 to 5 infiltrations with a 1-month period. Total regression was obtained in 25 keloids and hypertrophic scars. Important regression was obtained in 6 keloids (86% good results). Treatment was effective in all cases within the first 2 infiltrations evidenced by a reduction in the volume of the keloid and clear reduction of functional impairment in most patients.


CONCLUSIONS
Effective well-tolerated treatment without pain was achieved with infiltration suggesting that this treatment should be used as first line therapy for keloids.
Bodokh
I
I
Hôpital des Broussailles, Cannes.
Brun
P
P
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage* / Q000627:therapeutic use; D001761:Bleomycin / Q000008:administration & dosage* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D007627:Keloid / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
D000903:Antibiotics, Antineoplastic; D001761:Bleomycin
Traitement des chéloïdes par infiltrations de bléomycine.