title: Transjugular intrahepatic portosystemic shunt for bleeding angiodysplasia-like lesions in portal-hypertensive colopathy.
abstract: Portal-hypertensive colopathy has attracted interest in recent years because such lesions can cause life-threatening hemorrhage. In contrast to upper gastrointestinal bleeding from varices, there is no established therapy for bleeding from angiodysplasia-like lesions. This case report describes the first successful use of transjugular intrahepatic portosystemic shunt (TIPS) for long-term control of bleeding from angiodysplasia-like colonic lesions in a patient with cirrhosis caused by chronic hepatitis B infection. During an 18-month course after TIPS, angiodysplasia-like lesions disappeared without any further evidence of recurrent hematochezia. TIPS may be helpful as second-line treatment in patients with recurrent portal-hypertensive bleeding from colonic angiodysplasia-like lesions who do not tolerate or are unresponsive to treatment with beta-adrenergic blockers.
authors.affiliation: First Department of Medicine, Martin-Luther-University Halle-Wittenberg, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Balzer
authors.forename: E
authors.initials: E
authors.lastname: Lotterer
authors.forename: G
authors.initials: G
authors.lastname: Kleber
authors.forename: W E
authors.initials: WE
authors.lastname: Fleig
mesh_terms: D000368:Aged; D016888:Angiodysplasia / Q000150:complications*; D003108:Colonic Diseases / Q000628:therapy*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000628:therapy*; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications*; D019168:Portasystemic Shunt, Transjugular Intrahepatic; D012008:Recurrence