title: Cardiac manifestations in tuberous sclerosis: a 10-year review.
abstract: OBJECTIVE
  Tuberous sclerosis is a genetic disorder with multisystem involvement. The aim of this study was to focus primarily on the cardiac aspects of this condition.
  
  
  METHODS
  This review included 10 children with tuberous sclerosis presenting to our department during a 10-year period.
  
  
  RESULTS
  From our data, 80% were found to have cardiac involvement. There was an equal prevalence of neurologic complications.
  
  
  CONCLUSIONS
  Cardiac tumours and seizures were the most common problems encountered. Whereas most patients had no symptoms referable to the cardiovascular system and required no active intervention, many of those with neurologic involvement needed appropriate treatment.
authors.affiliation: Department of Paediatrics, National University of Singapore, Singapore.
authors.forename: S C
authors.initials: SC
authors.lastname: Quek
authors.forename: W
authors.initials: W
authors.lastname: Yip
authors.forename: S T
authors.initials: ST
authors.lastname: Quek
authors.forename: S K
authors.initials: SK
authors.lastname: Chang
authors.forename: M L
authors.initials: ML
authors.lastname: Wong
authors.forename: P S
authors.initials: PS
authors.lastname: Low
mesh_terms: D001921:Brain / Q000473:pathology; D001932:Brain Neoplasms / Q000175:diagnosis / Q000235:genetics*; D002648:Child; D002675:Child, Preschool; D003952:Diagnostic Imaging; D005260:Female; D006338:Heart Neoplasms / Q000175:diagnosis / Q000235:genetics*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009206:Myocardium / Q000473:pathology; D009460:Neurologic Examination; D012640:Seizures / Q000209:etiology; D014402:Tuberous Sclerosis / Q000175:diagnosis / Q000235:genetics*