[Experimental reconstruction of the sheep orbit with biodegradable implants].
In a complex animal model in sheep, polydioxanone (PDS) and polylactic membranes were used for the reconstruction of large orbital-wall defects. In a long-term experiment over 1 year, polylactic implants alone showed the best performance as compared with combinations involving autogenous bone grafts and titanium miniplate fixation. As soon as these polylactic implants are approved for human surgery, they will be used to solve the still challenging problem of anatomical reconstruction of large comminuted fractures of more than one orbital wall.
de Roche
R
R
Universitätsklinik für Wiederherstellende Chirurgie, Basel.
Kuhn
A
A
de Roche-Weber
P
P
Gogolewski
S
S
Printzen
G
G
Geissmann
A
A
De Jager
M
M
Hammer
B
B
Prein
J
J
Rahn
B
B
D000818:Animals; D001672:Biocompatible Materials; D001673:Biodegradation, Environmental; D005549:Foreign-Body Reaction / Q000473:pathology; D019344:Lactic Acid; D008422:Materials Testing; D009915:Orbit / Q000473:pathology / Q000601:surgery*; D016687:Polydioxanone; D011091:Polyesters; D011108:Polymers; D019919:Prosthesis Implantation; D012756:Sheep
D001672:Biocompatible Materials; D011091:Polyesters; D011108:Polymers; D016687:Polydioxanone; D019344:Lactic Acid; C033616:poly(lactide)
Experimentelle Rekonstruktion der Orbita beim Schaf mit biodegradablen Implantaten.