[Case report of a female patient with autoimmune hemolytic anemia and cold agglutinin antibodies].
We report a case of acute transient cold agglutinin disease, the etiology of which we could not determine with the available methods. Cold autoagglutinins had anti I specificity, high titers of the autoantibody (> 1:1,000) and the thermal range was relative wide. Our patient had severe haemolysis and immunosuppressive therapy with methylprednisolone and cyclophosphamide was administered. It is a question how much these immunosuppresive agents influenced the recovery, and in what extent it was a self limited disease with spontaneous recovery.
Konja
J
J
Klinika za pedijatriju Salata, Klinicki bolnicki centar, Zavod za hematologiju i onkologiju, Zagreb.
Jakovljević
G
G
Jaksić
B
B
Grgicević
D
D
Car
M
M
Glavas
B
B
D000373:Agglutinins / Q000276:immunology*; D000744:Anemia, Hemolytic, Autoimmune / Q000276:immunology* / Q000628:therapy; D001323:Autoantibodies / Q000032:analysis*; D002648:Child; D003080:Cold Temperature; D003450:Cryoglobulins; D005260:Female; D006801:Humans
D000373:Agglutinins; D001323:Autoantibodies; D003450:Cryoglobulins; C029443:cold agglutinins
Prikaz bolesnice s autoimunom hemolitickom anemijom s hladnim protutijelima.