title: [Micromycetes extracellular proteinases with fibrinolytic and anticoagulant properties].
abstract: One hundred and sixteen strains of microscopic fungal belonging to different taxonomic groups were tested for their ability ti synthesize extracellular proteinases with caseinolytic, fibrinolytic, plasminogen activator-like, and anticoagulant (prolonging the partial thromboplastin time) activities. Several producers of anticoagulants prolonging the partial thromboplastin time, probably via the activation of the protein C system, were revealed. The effectiveness of the fungal anticoagulants was close to that of the protein C activators from Agkistrodon snake venom.
authors.affiliation: Moscow State University, Vorob'evy gory, Russia.
authors.forename: N S
authors.initials: NS
authors.lastname: Landau
authors.forename: A V
authors.initials: AV
authors.lastname: Kurakov
authors.forename: O M
authors.initials: OM
authors.lastname: Gulikova
authors.forename: B
authors.initials: B
authors.lastname: Batomunkueva
authors.forename: S M
authors.initials: SM
authors.lastname: Strukova
authors.forename: N S
authors.initials: NS
authors.lastname: Egorov
mesh_terms: D000925:Anticoagulants / Q000378:metabolism*; D002364:Caseins / Q000378:metabolism; D010450:Endopeptidases / Q000096:biosynthesis / Q000378:metabolism*; D005343:Fibrinolytic Agents / Q000378:metabolism*; D005658:Fungi / Q000145:classification / Q000201:enzymology*; D006868:Hydrolysis; D010960:Plasminogen Activators / Q000378:metabolism; D013045:Species Specificity
chemical_list: D000925:Anticoagulants; D002364:Caseins; D005343:Fibrinolytic Agents; D010450:Endopeptidases; D010960:Plasminogen Activators
vernacular_title: Ekstratselliularnye proteinazy mikromitsetov s fibrinoliticheskimi i antikoaguliantnymi svoĭstvami.