title: Baló's concentric sclerosis in a 4-year-old Japanese infant.
abstract: We report the youngest known case with Baló's concentric sclerosis (Baló's disease), a variant of multiple sclerosis. This 4-year-old Japanese boy was diagnosed by clinical manifestations and by characteristic findings on magnetic resonance imaging (MRI). Dexamethasone was given intravenously, 3 mg twice daily for 10 days. The clinical manifestations were resolved within 2 weeks, and the MRI findings were markedly improved after 3 weeks. Following the initiation of steroid therapy, he showed remarkable clinical and physical improvement. It cannot be excluded that the clinical improvement resulted from the steroid therapy.
authors.affiliation: Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume City, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Murakami
authors.forename: T
authors.initials: T
authors.lastname: Matsuishi
authors.forename: T
authors.initials: T
authors.lastname: Shimizu
authors.forename: Y
authors.initials: Y
authors.lastname: Yamashita
authors.forename: S
authors.initials: S
authors.lastname: Nagamitsu
authors.forename: K
authors.initials: K
authors.lastname: Kojima
authors.forename: H
authors.initials: H
authors.lastname: Kato
authors.forename: T
authors.initials: T
authors.lastname: Tabira
mesh_terms: D001921:Brain / Q000473:pathology; D002675:Child, Preschool; D003907:Dexamethasone / Q000627:therapeutic use; D002549:Diffuse Cerebral Sclerosis of Schilder / Q000175:diagnosis* / Q000188:drug therapy* / Q000503:physiopathology; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D007275:Injections, Intravenous; D007564:Japan; D008279:Magnetic Resonance Imaging; D008297:Male; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D003907:Dexamethasone