title: Reduction of intraocular pressure in a glaucoma patient undergoing hormone replacement therapy.
abstract: OBJECTIVE
  To show the reducing effect of estrogens and progestins on the elevated intraocular pressure (IOP) in the case of a 56-year-old woman showing typical climacteric complaints, who was admitted to the menopause outpatient unit. She also suffered from a primary open-angle glaucoma treated with betaophtiole eye drops with intraocular pressures of 16-20 mmHg under this local therapy.
  
  
  METHODS
  IOP patterns were monitored by means of standardised daily pressure profiles four times a day before as well as 4 and 12 weeks after the beginning of hormone replacement therapy (HRT). The local glaucoma therapy remained unchanged.
  
  
  RESULTS
  During HRT, IOP levels were reduced from 16-20 mmHg before therapy to 12-15 mmHg at week 4 and to 13-15 mmHg at week 12 after the beginning of HRT.
  
  
  CONCLUSIONS
  The finding of a close chronological relationship between the onset of menopause and the development of a glaucoma is a potentially new indication for HRT.
authors.affiliation: Department of Obstetrics and Gynecology, General Hospital, University of Vienna, Austria. Michael.Sator@akh-wien.ac.at
authors.forename: M O
authors.initials: MO
authors.lastname: Sator
authors.forename: J
authors.initials: J
authors.lastname: Akramian
authors.forename: E A
authors.initials: EA
authors.lastname: Joura
authors.forename: A
authors.initials: A
authors.lastname: Nessmann
authors.forename: A
authors.initials: A
authors.lastname: Wedrich
authors.forename: D
authors.initials: D
authors.lastname: Gruber
authors.forename: M
authors.initials: M
authors.lastname: Metka
authors.forename: J C
authors.initials: JC
authors.lastname: Huber
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D004958:Estradiol / Q000627:therapeutic use*; D015914:Estrogen Replacement Therapy; D005260:Female; D005901:Glaucoma / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D007429:Intraocular Pressure / Q000187:drug effects*; D014290:Metipranolol / Q000627:therapeutic use; D008875:Middle Aged; D017698:Postmenopause; D011374:Progesterone / Q000627:therapeutic use*
chemical_list: D000959:Antihypertensive Agents; D011374:Progesterone; D004958:Estradiol; D014290:Metipranolol