title: Treatment of incomplete analgesia after placement of an epidural catheter and administration of local anesthetic for women in labor.
abstract: BACKGROUND
  Approximately 15% of women still have pain after placement of an epidural catheter and administration of local anesthetic for labor analgesia. Two techniques frequently used to treat this pain were compared: (1) withdrawal of the catheter 1 cm and repeated dosing with additional local anesthetic, and (2) repeated dosing with additional local anesthetic without any catheter manipulation.
  
  
  METHODS
  Fifteen minutes after placement of a multiple-orifice epidural catheter 5 cm into the epidural space and administration of 13 ml 0.25% bupivacaine to the parturient in labor, the adequacy of analgesia was assessed. All women who had incomplete analgesia were randomized (first intervention) to receive an additional 5 ml 0.25% bupivacaine (local-anestheticonly group) or to receive 5 ml 0.25% bupivacaine after first withdrawing the epidural catheter 1 cm (catheter-manipulation group). If after 15 min the woman still had pain, then (second intervention) the catheter was withdrawn 1 cm and an additional 5 ml 0.25% bupivacaine was administered to the local-anesthetic-only group, whereas 5 ml 0.25% bupivacaine was given to the catheter-manipulation group without further catheter manipulation. The success rate of the second intervention was assessed 15 min later.
  
  
  RESULTS
  Seventy-eight women were enrolled in the study, 39 to each group. In the local-anesthetic-only group, 29 (74%) women were successfully treated with the first intervention and the remaining 10 (100%) were successfully treated with the second intervention. In the catheter-manipulation group, 30 (77%) were successfully treated with the first intervention and 7 (100%; 2 patients were not studied because of investigator error) were successfully treated with the second intervention (P=NS).
  
  
  CONCLUSIONS
  Administration of additional local anesthetic without first withdrawing the epidural catheter will effectively treat most women for whom analgesia is incomplete after the placement of an epidural catheter during labor.
authors.affiliation: Department of Anesthesiology and Obstetrics, Mount Sinai School of Medicine, New York, New York, USA. ybeilin@smtplink.mssm.edu
authors.forename: Y
authors.initials: Y
authors.lastname: Beilin
authors.forename: J
authors.initials: J
authors.lastname: Zahn
authors.forename: H H
authors.initials: HH
authors.lastname: Bernstein
authors.forename: B
authors.initials: B
authors.lastname: Zucker-Pinchoff
authors.forename: W J
authors.initials: WJ
authors.lastname: Zenzen
authors.forename: L A
authors.initials: LA
authors.lastname: Andres
mesh_terms: D015360:Analgesia, Epidural / Q000295:instrumentation / Q000379:methods*; D016362:Analgesia, Obstetrical / Q000295:instrumentation / Q000379:methods*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D002045:Bupivacaine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007743:Labor, Obstetric; D011247:Pregnancy
chemical_list: D000779:Anesthetics, Local; D002045:Bupivacaine