title: Chronic hepatitis C: early intervention.
abstract: Chronic hepatitis C infection is the most common liver disease in the United States; it accounts for up to 12,000 deaths annually and is the most common referral for liver transplantation. Recognition of acute infection is desirable because treatment may prevent chronicity. Interferon remains the primary treatment, but new agents and combinations are being developed.
authors.affiliation: University of Massachusetts Medical School, Department of Medicine, Framingham, USA.
authors.forename: R S
authors.initials: RS
authors.lastname: Koff
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use*; D003362:Cost-Benefit Analysis; D003663:Decision Trees; D018450:Disease Progression; D005260:Female; D019698:Hepatitis C, Chronic / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D006801:Humans; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000627:therapeutic use*; D016031:Liver Transplantation; D011994:Recombinant Proteins; D012008:Recurrence; D065227:Transfusion Reaction
chemical_list: D000998:Antiviral Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins