[Beta 2-microglobulin as a criterion of dysfunction in the regulation of proximal tubular activity in mercuric chloride-induced nephropathy].
Sublimate nephropathy--modelled pathology of proximal nephron--serves as illustration of a pathogenetic role in development of proximal tubular dysfunction of enhanced vasoconstrictive potential of angiotensin II in plasma, angiotensin II and thromboxane B2 in renal cortex. The multiple regression equation has been calculated. The proportional contribution of plasma angiotensin II, atrial natriuretic peptide of plasma, cortical angiotensin II, cortical thromboxane B2 to regulation of proximal nephron function was the following: 26.85, 32.72, 10.51 and 10.56%, respectively.
Rogovyĭ
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D000804:Angiotensin II / Q000032:analysis / Q000097:blood; D000818:Animals; D009320:Atrial Natriuretic Factor / Q000097:blood; D007672:Kidney Cortex / Q000737:chemistry; D007674:Kidney Diseases / Q000097:blood / Q000139:chemically induced* / Q000503:physiopathology; D007687:Kidney Tubules, Proximal / Q000503:physiopathology*; D008297:Male; D008627:Mercuric Chloride; D008962:Models, Theoretical; D051381:Rats; D012044:Regression Analysis; D013929:Thromboxane B2 / Q000032:analysis; D001613:beta 2-Microglobulin / Q000032:analysis*
D001613:beta 2-Microglobulin; D000804:Angiotensin II; D008627:Mercuric Chloride; D013929:Thromboxane B2; D009320:Atrial Natriuretic Factor
Beta2-mikroglobulin kak kriteriĭ disfunktsii reguliatsii deiatel'nosti proksimal'nykh kanal'tsev pri sulemovoĭ nefropatii.