Very low-dose cyclosporin treatment of steroid-resistant interstitial pneumonitis associated with Sjögren's syndrome.
Cyclosporin is known to be effective for both transplantation and a spectrum of immune-mediated diseases. Because this agent also causes severe adverse effects, especially nephrotoxicity, careful monitoring is required for the development of such reactions. Here we report the successful treatment with extremely low-dose cyclosporin (1 mg/kg/day) of a patient who had steroid-resistant interstitial pneumonitis and Sjögren's syndrome.
Ogasawara
H
H
Department of Internal Medicine, Juntendo University School of Medicine, Tokyo, Japan.
Sekiya
M
M
Murashima
A
A
Hishikawa
T
T
Tokano
Y
Y
Sekigawa
I
I
Iida
N
N
Hashimoto
H
H
Hirose
S
S
D016572:Cyclosporine / Q000008:administration & dosage*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000000981:diagnostic imaging / Q000188:drug therapy*; D014057:Tomography, X-Ray Computed
D016572:Cyclosporine