title: Hypersensitive allergic reactions to bismuth-iodoform-paraffin paste following ear surgery.
abstract: The case notes of 185 patients who had bismuth-iodoform-paraffin paste (BIPP) impregnated ribbon gauze used for packing following ear surgery were analysed retrospectively. The incidence of hypersensitive allergic reactions to BIPP was 5.9 per cent and a five-fold increase risk of developing allergic reactions was found in those with previous exposure to BIPP. Where temporalis fascia was used to repair tympanic membrane defects, the incidence of tympanic membrane graft perforations was higher when allergic reactions to BIPP developed post-operatively, compared to non-allergic cases.
authors.affiliation: Department of Otorhinolaryngology, Burton Hospital, UK. paul@medicine.med.um.edu.my
authors.forename: P V
authors.initials: PV
authors.lastname: Lim
authors.forename: R G
authors.initials: RG
authors.lastname: Hughes
authors.forename: J
authors.initials: J
authors.lastname: Oates
mesh_terms: D001729:Bismuth / Q000009:adverse effects*; D004338:Drug Combinations; D004342:Drug Hypersensitivity / Q000453:epidemiology* / Q000209:etiology; D006801:Humans; D006847:Hydrocarbons, Iodinated / Q000009:adverse effects*; D015994:Incidence; D008416:Mastoid / Q000601:surgery*; D009225:Myringoplasty; D011183:Postoperative Complications / Q000517:prevention & control*; D012086:Reoperation; D012189:Retrospective Studies; D014433:Tympanoplasty
chemical_list: D004338:Drug Combinations; D006847:Hydrocarbons, Iodinated; C045757:bismuth iodoform paraffin paste; D001729:Bismuth