title: [Treatment of post-traumatic acute anemia by recombinant human erythropoietin in Jehovah's Witnesses].
abstract: A 20-year-old Jehovah's witness patient experienced a femur fracture, with a section of the femoral artery and vein. On admission, haemoglobin concentration was 5.6 g.dL-1 and haematocrit 17%. Because of aponevrotomy, blood losses persisted. As the patient refused blood transfusion, recombinant human erythropoietin and parenteral iron were administered, associated with mild hypothermia, sedation and mechanical ventilation. After 21 days, the haemoglobin concentration increased to 10.9 g.dL-1 and haematocrit to 33% Recombinant human erythropoietin and parenteral iron may provide an alternative safe and effective therapy in life-threatening anaemia when blood transfusions are not accepted by the patient.
authors.affiliation: Service d'anesthésie chirurgicale, hôpitaux urbains, CHU, hôpital central, Nancy, France.
authors.forename: C
authors.initials: C
authors.lastname: Streef
authors.forename: C
authors.initials: C
authors.lastname: Charpentier
authors.forename: G
authors.initials: G
authors.lastname: Audibert
authors.forename: M C
authors.initials: MC
authors.lastname: Laxenaire
mesh_terms: D000208:Acute Disease; D000328:Adult; D000747:Anemia, Hypochromic / Q000188:drug therapy* / Q000209:etiology; D016063:Blood Loss, Surgical; D002835:Christianity; D004921:Erythropoietin / Q000627:therapeutic use*; D005263:Femoral Artery / Q000293:injuries* / Q000601:surgery; D005264:Femoral Fractures / Q000628:therapy; D005268:Femoral Vein / Q000293:injuries* / Q000601:surgery; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D008297:Male; D011994:Recombinant Proteins; D013997:Time Factors
chemical_list: D006454:Hemoglobins; D011994:Recombinant Proteins; D004921:Erythropoietin
vernacular_title: Traitement d'une anémie aiguë post-traumatique par érythropoïétine humaine recombinante chez un témoin de Jéhovah.