Combined blockade of CD28/B7 and CD40/CD40L costimulatory pathways prevents the onset of chronic rejection.
Subbotin
V
V
Thomas E. Starzl Transplantation Institute, Pittsburgh, PA 15213, USA.
Sun
H
H
Chen
C
C
Aitouche
A
A
Valdivia
L
L
Fung
J J
JJ
Starzl
T E
TE
Rao
A S
AS
D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology; D001011:Aorta / Q000637:transplantation*; D018122:B7-1 Antigen / Q000502:physiology*; D018106:CD28 Antigens / Q000502:physiology*; D019013:CD40 Antigens / Q000502:physiology*; D023201:CD40 Ligand; D002908:Chronic Disease; D006224:Cricetinae; D006084:Graft Rejection / Q000276:immunology* / Q000517:prevention & control*; D006801:Humans; D007132:Immunoglobulin Isotypes; D008562:Membrane Glycoproteins / Q000037:antagonists & inhibitors*; D051379:Mice; D008809:Mice, Inbred C3H; D008815:Mice, Inbred Strains; D014184:Transplantation, Homologous / Q000276:immunology*; D014185:Transplantation, Isogeneic / Q000276:immunology*
D000911:Antibodies, Monoclonal; D018122:B7-1 Antigen; D018106:CD28 Antigens; D019013:CD40 Antigens; D007132:Immunoglobulin Isotypes; D008562:Membrane Glycoproteins; D023201:CD40 Ligand