Isolation of 2-(3'-bromo-4'-hydroxyphenol)ethanamine from the New Zealand ascidian Cnemidocarpa bicornuta.
From the ascidian Cnemidocarpa bicornuta, 2-(3'-bromo-4'-hydroxyphenol)ethanamine (3'-bromotyramine) (1) has been isolated along with the previously reported sponge metabolite, 1,3-dimethylisoguanine. The structure of 1 was confirmed by synthesis.
Lindsay
B S
BS
Department of Chemistry, University of Auckland, Private Bag 92019, Auckland, New Zealand.
Battershill
C N
CN
Copp
B R
BR
D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects; D002176:Candida albicans; D002851:Chromatography, High Pressure Liquid; D007941:Leukemia P388 / Q000188:drug therapy; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D051379:Mice; D008826:Microbial Sensitivity Tests; D009520:New Zealand; D051381:Rats; D013056:Spectrophotometry, Ultraviolet; D014439:Tyramine / Q000031:analogs & derivatives* / Q000302:isolation & purification / Q000494:pharmacology; D014561:Urochordata / Q000737:chemistry*
C113243:2-(3'-bromo-4'-hydroxyphenol)ethanamine; D000970:Antineoplastic Agents; D014439:Tyramine