title: In vitro study of BCX-34: a new human T-lymphocyte-specific purine phosphorylase inhibitor.
authors.affiliation: Department of Urology, Metic Transplantation Laboratories, University of Southern California School of Medicine, Los Angeles 90057, USA.
authors.forename: H
authors.initials: H
authors.lastname: Iwata
authors.forename: Y
authors.initials: Y
authors.lastname: Wada
authors.forename: M
authors.initials: M
authors.lastname: Walsh
authors.forename: J A
authors.initials: JA
authors.lastname: Montgomery
authors.forename: H
authors.initials: H
authors.lastname: Hirose
authors.forename: R
authors.initials: R
authors.lastname: Mendez
authors.forename: J
authors.initials: J
authors.lastname: Cicciarelli
authors.forename: Y
authors.initials: Y
authors.lastname: Iwaki
mesh_terms: D000818:Animals; D002461:Cell Line, Transformed; D003849:Deoxyguanosine / Q000494:pharmacology; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006147:Guanine / Q000031:analogs & derivatives* / Q000494:pharmacology; D006801:Humans; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007376:Interleukin-2 / Q000096:biosynthesis; D019169:Jurkat Cells; D007700:Kinetics; D007959:Lymphocyte Culture Test, Mixed; D051379:Mice; D008810:Mice, Inbred C57BL; D011683:Purine-Nucleoside Phosphorylase / Q000037:antagonists & inhibitors*; D051381:Rats; D011916:Rats, Inbred F344; D013154:Spleen / Q000276:immunology; D013601:T-Lymphocytes / Q000187:drug effects / Q000201:enzymology / Q000276:immunology*
chemical_list: D004791:Enzyme Inhibitors; D007166:Immunosuppressive Agents; D007376:Interleukin-2; D006147:Guanine; C104194:peldesine; D011683:Purine-Nucleoside Phosphorylase; D003849:Deoxyguanosine