Molecular cloning of a gene encoding phospholipase D from the pathogenic and dimorphic fungus, Candida albicans.
A phospholipase D gene (CaPLD) has been cloned from the Candida albicans genomic DNA library. The CaPLD is a member of a highly conserved gene family of PLD and has the highest homology to Saccharomyces cerevisiae PLD (SPO14) with an overall homology of 42%. Phylogenetic analysis indicated that fungus PLDs including CaPLD composed one of the three clusters of PLD genes.
Kanoh
H
H
Department of Dermatology, Gifu University School of Medicine, Tsukasamachi-40, Gifu 500-8076, Japan.
Nakashima
S
S
Zhao
Y
Y
Sugiyama
Y
Y
Kitajima
Y
Y
Nozawa
Y
Y
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D002176:Candida albicans / Q000201:enzymology* / Q000235:genetics; D003001:Cloning, Molecular; D004271:DNA, Fungal; D006801:Humans; D008969:Molecular Sequence Data; D010739:Phospholipase D / Q000145:classification / Q000235:genetics*; D017386:Sequence Homology, Amino Acid
D004271:DNA, Fungal; D010739:Phospholipase D