Sarcoidosis with orbital tumor outside the lacrimal gland: initial manifestation in 2 elderly white women.
Two elderly white women (aged 72 and 87 years) were first seen with painless, unilateral orbital swelling. Orbital scanning revealed masses infiltrating the soft tissue around the eye. Biopsy results showed nodular, noncaseating granulomas consistent with sarcoidosis. One patient's workup revealed systemic manifestations of sarcoidosis at the time of examination with hilar lymphadenopathy noted on gallium scan; the other refused a complete systemic workup. The orbital tumors resolved with systemic prednisone therapy. To our knowledge, our 87-year-old patient is the oldest to be seen with orbital sarcoidosis. These 2 patients demonstrate that this diagnosis must be considered with orbital tumors in the elderly and in unusual locations, such as these which occurred outside the lacrimal gland.
Peterson
E A
EA
Department of Ophthalmology, John A. Moran Eye Center, University of Utah Health Sciences Center, Salt Lake City 84132, USA.
Hymas
D C
DC
Pratt
D V
DV
Mortenson
S W
SW
Anderson
R L
RL
Mamalis
N
N
D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008206:Lymphatic Diseases / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D008279:Magnetic Resonance Imaging; D009916:Orbital Diseases / Q000150:complications / Q000188:drug therapy / Q000473:pathology; D016727:Orbital Pseudotumor / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D011241:Prednisone / Q000627:therapeutic use; D012507:Sarcoidosis / Q000150:complications* / Q000188:drug therapy / Q000473:pathology; D014057:Tomography, X-Ray Computed
D005938:Glucocorticoids; D011241:Prednisone