title: Images of psychopathology.
abstract: Brain imaging continues to provide important data about brain structure, neurotransmitter function and the physiological basis of cognitive processes, as these relate to schizophrenia and mood disorders. A unifying theoretical perspective, however, that can clarify the precise nature of the biological basis of these diverse psychiatric conditions is lacking. It is becoming increasingly evident that a lesion model is inappropriate and that a more relevant characterisation will be found in terms of disorders of functional interconnections between brain regions.
authors.affiliation: Wellcome Department of Cognitive Neurology, University College London, UK. cfrith@fil.ion.ucl.ac.uk
authors.forename: C
authors.initials: C
authors.lastname: Frith
authors.forename: R J
authors.initials: RJ
authors.lastname: Dolan
mesh_terms: D003863:Depression / Q000503:physiopathology; D003952:Diagnostic Imaging / Q000379:methods*; D004298:Dopamine / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D019964:Mood Disorders / Q000175:diagnosis* / Q000503:physiopathology; D012559:Schizophrenia / Q000175:diagnosis* / Q000503:physiopathology
chemical_list: D004298:Dopamine