title: [Computer-assisted training in genetically-induced neuropsychological deficits. A case report of a patient with de Grouchy syndrome I (chromosome 18 p syndrome)].
abstract: The present case study is a report on computer-based training approach in a male patient suffering from the de-Grouchy syndrome I (with a characteristic chromosomal deletion pattern), who along with psychotic symptoms displayed neuropsychological deficits. Participating in a well-established intervention programme aimed at a broad spectrum of psychological functions, the patient went through 36 training sessions. With regard to outcome assessments one focus was on improved performance in the training tasks, while the other one referred to transfer effects, as indexed by a neuropsychological test battery which was given before and after the entire programme. In both areas substantial gains from training emerged according to the collected data. In view of these results neuropsychological training approaches appear to have a perspective even in behavioural deficits with a genetic basis.
authors.affiliation: Zentralinstitut für Seelische Gesundheit, Mannheim.
authors.forename: R
authors.initials: R
authors.lastname: Olbrich
authors.forename: C
authors.initials: C
authors.lastname: Wöhrle
authors.forename: S
authors.initials: S
authors.lastname: Cohen
mesh_terms: D000328:Adult; D002872:Chromosome Deletion; D002887:Chromosomes, Human, Pair 18; D003072:Cognition Disorders / Q000235:genetics* / Q000523:psychology / Q000534:rehabilitation; D003194:Computer-Assisted Instruction; D006801:Humans; D008297:Male; D019965:Neurocognitive Disorders / Q000235:genetics* / Q000523:psychology / Q000534:rehabilitation; D009483:Neuropsychological Tests; D013813:Therapy, Computer-Assisted; D016896:Treatment Outcome
vernacular_title: Computergestütztes Training bei genetisch bedingten neuropsychologischen Defiziten. Eine kasuistische Darstellung bei einem Patienten mit de-Grouchy-Syndrom I (Chromosom 18 p-Syndrom).