title: 1-[2(R)-(2-amino-2-methylpropionylamino)-3-(1H-indol-3-yl)propionyl]- 3-benzylpiperidine-3(S)-carboxylic acid ethyl ester (L-163,540): a potent, orally bioavailable, and short-duration growth hormone secretagogue.
authors.affiliation: Merck Research Laboratories, Rahway, New Jersey 07065, USA.
authors.forename: L
authors.initials: L
authors.lastname: Yang
authors.forename: G
authors.initials: G
authors.lastname: Morriello
authors.forename: A A
authors.initials: AA
authors.lastname: Patchett
authors.forename: K
authors.initials: K
authors.lastname: Leung
authors.forename: T
authors.initials: T
authors.lastname: Jacks
authors.forename: K
authors.initials: K
authors.lastname: Cheng
authors.forename: K D
authors.initials: KD
authors.lastname: Schleim
authors.forename: W
authors.initials: W
authors.lastname: Feeney
authors.forename: W W
authors.initials: WW
authors.lastname: Chan
authors.forename: S H
authors.initials: SH
authors.lastname: Chiu
authors.forename: R G
authors.initials: RG
authors.lastname: Smith
mesh_terms: D000284:Administration, Oral; D000818:Animals; D001682:Biological Availability; D018360:Crystallography, X-Ray; D004285:Dogs; D004952:Esters / Q000008:administration & dosage / Q000138:chemical synthesis* / Q000493:pharmacokinetics / Q000494:pharmacology; D013006:Growth Hormone / Q000097:blood / Q000378:metabolism*; D066298:In Vitro Techniques; D008297:Male; D010880:Piperidines / Q000008:administration & dosage / Q000138:chemical synthesis* / Q000493:pharmacokinetics / Q000494:pharmacology; D010902:Pituitary Gland / Q000166:cytology / Q000187:drug effects / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D013237:Stereoisomerism
chemical_list: D004952:Esters; C113159:L 163540; D010880:Piperidines; D013006:Growth Hormone