title: Intralymphatic embolic cells with cutaneous endometriosis in the umbilicus.
abstract: Endometriosis is defined as the presence of both functioning endometrial glands and stroma outside their usual location lining the uterine cavity. It has been identified in virtually all tissues and organs of the female body with the exception of the spleen. There have been many theories proposed regarding the etiology and pathogenesis of endometriosis. One is the transport of cells through lymphatics and blood vessels. A 44-year-old female suffering from an episode of endometriosis of the umbilicus, left inguinal, uterus, and bilateral ovaries in association with a Múllerian anomaly is presented. Histopathological findings of a skin biopsy from her umbilicus showed aggregated cells within the lymphatic vessel of the upper dermis. This case provides evidence suggesting that cutaneous endometriosis could occur by transport of endometrial cells through lymphatics or blood vessels.
authors.affiliation: Department of Dermatology, Yamaguchi University School of Medicine, Ube, Japan.
authors.forename: M
authors.initials: M
authors.lastname: Ichimiya
authors.forename: T
authors.initials: T
authors.lastname: Hirota
authors.forename: M
authors.initials: M
authors.lastname: Muto
mesh_terms: D004715:Endometriosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis / Q000473:pathology*; D008875:Middle Aged; D009360:Neoplastic Cells, Circulating / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*; D014472:Umbilicus / Q000473:pathology*