Dual renal grafts: expansion of the donor pool from an overlooked source.
This is a review of the emerging practice of dual renal allografting. In the setting of the expanded criteria cadaveric (and usually older) donor with inadequate function to allow single kidney transplantation, both kidneys have been transplanted into a single recipient. The recipient and donor have often been matched for age and size as dictated by the concept of nephron dosing. The reported results of dual grafting are excellent and statistically comparable to contemporaneous single cadaveric grafts. Criteria are evolving regarding when to apply single or dual grafting. Wider acceptance of dual renal grafting could have a significant impact on the cadaver kidney shortage.
Dafoe
D C
DC
Department of Surgery, Stanford University School of Medicine, CA 94305-5342, USA.
Alfrey
E J
EJ
D006801:Humans; D016030:Kidney Transplantation / Q000379:methods*; D014019:Tissue Donors