title: Synovial metaplasia in lipoma.
abstract: We present a unique case of a lipoma with widespread synovial metaplasia. A 52-year-old woman had a recurrence 1 year after excision of a subcutaneous lipoma of the neck. Histologically, the primary tumor was an ordinary lipoma. The recurrent tumor was a myxoid lipoma with synovial metaplasia. The synovial metaplastic process manifested as labyrinthlike clefts, which were lined by one or more synovial-like cell layers. Ultrastructurally, the synovial metaplastic cell had secretory, phagocytic, and fibroblastlike features.
authors.affiliation: Soft Tissue Tumor Registry, Sikl's Department of Pathology, Faculty Hospital, Pilsen, Czech Republic.
authors.forename: M
authors.initials: M
authors.lastname: Michal
authors.forename: M
authors.initials: M
authors.lastname: Zámecník
mesh_terms: D005260:Female; D006801:Humans; D008067:Lipoma / Q000150:complications / Q000473:pathology* / Q000648:ultrastructure; D008679:Metaplasia / Q000150:complications / Q000473:pathology; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012867:Skin / Q000473:pathology / Q000648:ultrastructure; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology* / Q000648:ultrastructure; D013583:Synovial Membrane / Q000473:pathology* / Q000648:ultrastructure