[Effects of ATP on intracellular free [Ca2+]i in isolated cochlear OHC].
The effect of adenosine triphosphate (ATP) upon intracellular free calcium concentration ([Ca2+]i) of cochlear outer hair cell (OHC) isolated from guinea pigs was studied. Stained with fluorescence, [CA2+]i was measured using ACAS 570. ATP significantly increased the [Ca2+]i level, which then dropped rapidly from the peak value it rose again reaction after readdtion of ATP. This result indicates that ATP is a nerve transmitter acting on the outer hair cells.
Li
Y
Y
Zhujiang Hospital, First Military Medical University, Guangzhou.
Huang
Y
Y
D000255:Adenosine Triphosphate / Q000494:pharmacology*; D000818:Animals; D002118:Calcium / Q000378:metabolism*; D002478:Cells, Cultured; D005260:Female; D006168:Guinea Pigs; D018072:Hair Cells, Auditory, Outer / Q000378:metabolism*; D008297:Male
D000255:Adenosine Triphosphate; D002118:Calcium