Steroid withdrawal in renal transplant recipients: pro point of view.
Steroid-free immunosuppression remains an attractive goal in an era in which the transplant community should be promoting long-term allograft survival by reducing cardiovascular risk and maximizing long-term patient survival. In the cyclosporine era, the risks of steroid withdrawal outweighed the benefits of steroid withdrawal in a substantial minority of patients. A number of new immunosuppressants may prove to be more steroid sparing than cyclosporine alone and promise to increase the safety of steroid-free immunosuppression for renal transplant recipients.
Hricik
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Department of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
D003365:Costs and Cost Analysis; D004334:Drug Administration Schedule; D006084:Graft Rejection / Q000453:epidemiology / Q000517:prevention & control; D006801:Humans; D007165:Immunosuppression Therapy / Q000191:economics / Q000379:methods*; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016030:Kidney Transplantation / Q000191:economics / Q000276:immunology* / Q000401:mortality; D015166:Monitoring, Immunologic; D011183:Postoperative Complications; D012307:Risk Factors; D013256:Steroids / Q000008:administration & dosage / Q000627:therapeutic use*; D015996:Survival Rate
D007166:Immunosuppressive Agents; D013256:Steroids