[Study on the immune state of patients with laryngeal carcinoma].
The authors have carried out the immunoassay on 68 patients with laryngeal carcinoma in order to investigate the relationship between the occurrence and development of the tumour and the body immune state by using the methods of R1D, APAAP and LDH. The results showed that, in comparison with the normal group, CD3+, CD4+ cell and NK cell activity were much lower (P < 0.01), CD8+ cell slightly increased (P > 0.05). IgG, IgA and IgM were also lower (P < 0.05). It indicates that the lower level of cellular immunity, the descent of the ratio of CD4+/CD8+ and the condition which suppresses the body immune system are the interior factors which make the laryngeal carcinoma happening and developing easily. With the development of tumor, the increase of various suppressor factors and the immune system suppressed further the tumor can spread and shift much more easily.
Li
Y
Y
Department of Otolaryngology, Shandong Provincial Hospital, Jinan.
Che
Z
Z
Liang
M
M
D000328:Adult; D000368:Aged; D016516:CD4-CD8 Ratio; D002294:Carcinoma, Squamous Cell / Q000276:immunology*; D006801:Humans; D007694:Killer Cells, Natural / Q000276:immunology; D007822:Laryngeal Neoplasms / Q000276:immunology*; D008297:Male; D008875:Middle Aged; D016176:T-Lymphocyte Subsets / Q000276:immunology*