Effect of guarana on exercise in normal and epinephrine-induced glycogenolytic mice.
The tonic action of water Guarana extract, (Paullinia cupana MART.), was investigated in normal, exercised, and epinephrine-induced glycogenolytic mice. A water extract of Guarana (GW) (500 mg/kg) increased the blood glucose level (p < 0.001) and decreased the liver glycogen contents of mice 60 min after oral maltose administration (p < 0.05). GW also significantly suppressed exercise-induced hypoglycemia (60 min: p < 0.05). However, GW did not affect the blood glucose in epinephrine-induced glycogenolytic and exercise mice. These findings indicate that the suppressive mechanism of hypoglycemia might be due to the promotion of glycogen resolution.
Miura
T
T
Department of Clinical Nutrition, Suzuka University of Medical Science, Faculty of Health Science, Mie, Japan.
Tatara
M
M
Nakamura
K
K
Suzuki
I
I
D000818:Animals; D001786:Blood Glucose / Q000032:analysis; D002110:Caffeine / Q000494:pharmacology*; D004338:Drug Combinations; D004837:Epinephrine / Q000494:pharmacology*; D005215:Fasting; D006003:Glycogen / Q000378:metabolism*; D008297:Male; D008320:Maltose; D051379:Mice; D010805:Physical Conditioning, Animal; D012639:Seeds / Q000737:chemistry*; D013805:Theobromine / Q000494:pharmacology*; D013806:Theophylline / Q000494:pharmacology*
D001786:Blood Glucose; D004338:Drug Combinations; C092099:guarana powder; D002110:Caffeine; D008320:Maltose; D006003:Glycogen; D013806:Theophylline; D013805:Theobromine; D004837:Epinephrine