Accelerated phase of chronic myeloid leukemia presenting with hypercalcemia and a mediastinal mass.
A patient with chronic myeloid leukemia developed hypercalcemia as a presenting sign of the accelerated phase of the disease. Ultrasound of the neck showed a large hypodense mass connected to the thyroid gland, which was thought to be a parathyroid tumor and the cause of the hypercalcemia. Histology of the surgically removed mass revealed a chloroma. The patient's course was complicated by respiratory failure and metastatic calcinosis of the lung, an unusual finding in hypercalcemia of short duration.
Quitt
M
M
Institute of Hematology, Lady Davis Carmel Hospital, Haifa, Israel.
Kelner
J
J
Sova
J
J
Froom
P
P
Aghai
E
E
D002114:Calcinosis / Q000209:etiology; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000209:etiology*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D008171:Lung Diseases / Q000209:etiology; D008482:Mediastinum / Q000473:pathology* / Q000601:surgery; D008875:Middle Aged