[Which treatment should children with recurrent urinary infections, without anatomical anomalies, receive?].
OBJECTIVE
To determine the best treatment for children with recurrent infection of the lower urinary tract and without anatomical abnormalities.


METHODS
A clinical study was conducted on 150 children (30 boys and 120 girls), aged 4 to 36 months (mean 16), with recurrent urinary tract infections (UTI) and no radiological evidence of anatomical abnormalities. They were divided into three groups: group I was treated with a single nightly prophylactic dose of an antibiotic; group II received a single nightly dose of oxybutinin, or divided in 2-4 doses; group III received a single nightly prophylactic dose of an antibiotic and oxybutinin as in group II.


RESULTS
There were more episodes of UTI in group I (44/50), more hospitalizations and problems of malnutrition, and a longer period of treatment was required. In group II, 14/50 children had episodes of UTI, their nutritional status improved and there were less hospitalizations. In group III, 3/50 children had episodes of UTI; they were the best responders and required a shorter duration of treatment.


CONCLUSIONS
Prophylactic therapy requires a longer period of treatment. The use of oxybutinin is an alternative modality in the treatment of these children. Combination therapy with a single nightly dose of an antibiotic and anticholinergic (oxybutinin) appears to be the best therapeutic modality for children with recurrent UTI and no anatomical abnormality.
Granados
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EA
Clínica y Hospital de Especialidades, Quetzaltenango, Guatemala.
D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012008:Recurrence; D014552:Urinary Tract Infections / Q000188:drug therapy*
Qué tratamiento deben de recibir los niños con infecciones de orina recurrentes, sin anomalías anatómicas?