title: Registration of synthetic tomographic projection data sets using cross-correlation.
abstract: Tomographic registration, a method that makes possible accurate patient registration directly from projection data, consists of three processing steps: (i) manual coarse positioning, (ii) tomographic projection set acquisition, and (iii) computer mediated refined positioning. In the coarse positioning stage, the degree of patient alignment is comparable with that achieved with the standard radiotherapy set-up. However, the accuracy requirements are somewhat more relaxed in that meticulous alignment of the patient using external laser indicators is not necessary. Instead, tomographic projection sets are compared with planning CTs in order to achieve improved patient set-up. The projection sets are cross-correlated to obtain the best-fit translation and rotation offsets. The algorithm has been tested on synthetic data with the incorporation of varying amounts of Gaussian pseudo-random noise. These tests demonstrate the algorithm's stability and also confirm that alignment can be achieved with an accuracy of less than one projection pixel.
authors.affiliation: Department of Medical Physics, University of Wisconsin-Madison, 53706, USA.
authors.forename: E E
authors.initials: EE
authors.lastname: Fitchard
authors.forename: J S
authors.initials: JS
authors.lastname: Aldridge
authors.forename: P J
authors.initials: PJ
authors.lastname: Reckwerdt
authors.forename: T R
authors.initials: TR
authors.lastname: Mackie
mesh_terms: D000465:Algorithms; D001699:Biometry; D055592:Biophysical Phenomena; D001703:Biophysics; D006801:Humans; D008962:Models, Theoretical; D009369:Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy; D019047:Phantoms, Imaging; D011880:Radiotherapy Planning, Computer-Assisted / Q000706:statistics & numerical data; D011882:Radiotherapy, High-Energy / Q000295:instrumentation / Q000706:statistics & numerical data; D013679:Technology, Radiologic; D014057:Tomography, X-Ray Computed / Q000706:statistics & numerical data*