[Clinical experience with enzymes (collagenase, protease) in the treatment of skin lesions caused by CO2-laser surgery].
The authors applied collagenase and protease in lipofil solution for the treatment of skin lesions caused by CO2 laser interventions. 354 surgical interventions were performed on 91 patients (43 verruca vulgaris, 32 naevus intradermalis, 16 keratosis). The laser methods were excision or/and vaporisation of the lesion. The authors created methodological groups and all of the patients had a control laser wounds without enzymatic treatment. The patients were controlled periodically from the 1st to the 56th postoperative day. The first experience shows that, the use of enzymatic treatment is advantageous for the laser wounds healing. The colour, scar formation and other aspects proved to be better after the enzymatic treatment. The optimal method was the use of the cream for 2-4 postoperative days on very thin layer, without bandage. The result seemed to be better compared with the enzymatically untreated cases.
Gáspár
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MH Központi Honvédkórház, Budapest, Szájsebészeti Osztály.
Bogdányi
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E
D000293:Adolescent; D000328:Adult; D017364:Collagenases / Q000627:therapeutic use*; D010450:Endopeptidases / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007642:Keratosis / Q000601:surgery*; D053685:Laser Therapy / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D009506:Nevus / Q000601:surgery*; D011182:Postoperative Care; D012867:Skin / Q000293:injuries; D014860:Warts / Q000601:surgery*
D010450:Endopeptidases; D017364:Collagenases
Enzimatikus sebkezeléssel (kollagenáz, proteáz) szerzett klinikai tapasztalataink brön végzett CO2-laser-sebészeti mütéteket követöen.