title: Regional and distant metastases in laryngeal and hypopharyngeal sarcomas.
abstract: Cervical node and distant metastases are the most important prognostic factors in malignant laryngeal neoplasms. Owing to the unusual occurrence of laryngeal sarcomas, the prevalence of their metastases has never been analyzed in detail. We reviewed the laryngeal sarcomas reported in the literature and noticed that both regional and distant metastases are rare events and variable for different histotypes. These observations have obvious therapeutic and prognostic implications.
authors.affiliation: Department of Otolaryngology, University of Brescia, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Nicolai
authors.forename: G
authors.initials: G
authors.lastname: Caruso
authors.forename: L O
authors.initials: LO
authors.lastname: Redaelli de Zinis
authors.forename: K O
authors.initials: KO
authors.lastname: Devaney
authors.forename: A
authors.initials: A
authors.lastname: Rinaldo
authors.forename: M
authors.initials: M
authors.lastname: Berlucchi
authors.forename: A
authors.initials: A
authors.lastname: Ferlito
mesh_terms: D006801:Humans; D007012:Hypopharyngeal Neoplasms / Q000473:pathology*; D007822:Laryngeal Neoplasms / Q000473:pathology*; D011379:Prognosis; D012509:Sarcoma / Q000556:secondary*