[Effects of antihypertensive therapy on renal function in nephrogenic hypertension].
Radionuclide tracing was performed to study renal function before and after hypotensive therapy in 95 patients suffering from nephrogenic hypertension with renal failure. It is shown that if hypotensive therapy in such patients brings about a blood pressure fall more than 25% of the initial blood pressure, renal function declines, the suppression being especially evident in severe renal insufficiency.
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D000328:Adult; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage / Q000494:pharmacology; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000494:pharmacology*; D001794:Blood Pressure / Q000187:drug effects*; D002216:Captopril / Q000008:administration & dosage / Q000494:pharmacology; D004232:Diuretics / Q000008:administration & dosage / Q000494:pharmacology; D004359:Drug Therapy, Combination; D005665:Furosemide / Q000008:administration & dosage / Q000494:pharmacology; D006801:Humans; D006852:Hydrochlorothiazide / Q000008:administration & dosage / Q000494:pharmacology; D006977:Hypertension, Renal / Q000188:drug therapy* / Q000503:physiopathology; D007668:Kidney / Q000187:drug effects*; D007676:Kidney Failure, Chronic / Q000150:complications*; D008875:Middle Aged; D011433:Propranolol / Q000008:administration & dosage / Q000494:pharmacology; D011866:Radioisotope Renography; D049993:Sodium Chloride Symporter Inhibitors / Q000008:administration & dosage / Q000494:pharmacology
D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D004232:Diuretics; D049993:Sodium Chloride Symporter Inhibitors; D006852:Hydrochlorothiazide; D005665:Furosemide; D002216:Captopril; D011433:Propranolol
Vliianie gipotenzivnoĭ terapii na funktsiiu pochek pri nefrogennoĭ gipertenzii.