title: Evaluation of a bioabsorbable physical barrier for guided bone regeneration. Part I. Material alone.
abstract: This study evaluates a prototype bioabsorbable physical barrier material for guided bone regeneration. Nonspacemaking dehiscence-type defects were surgically created in the right and left mandibles of six adult dogs. Each animal received six root-form threaded titanium implants. The osseous defects were randomized to receive treatment by either the prototype bioabsorbable barrier composed of a copolymer of lactide and glycolide, an expanded polytetrafluoroethylene nonresorbable barrier, or no barrier (control), Clinical and histologic results after 3.5 months of wound healing indicated that exposed threads were covered when treated with the expanded polytetrafluoroethylene barrier. Minimal thread coverage was evident with the bioabsorbable barrier and the control.
authors.affiliation: Periodontics Department, University of Texas Health Science Center at San Antonio 78284-7894, USA.
authors.forename: J T
authors.initials: JT
authors.lastname: Mellonig
authors.forename: M
authors.initials: M
authors.lastname: Nevins
authors.forename: R
authors.initials: R
authors.lastname: Sanchez
mesh_terms: D016301:Alveolar Bone Loss / Q000601:surgery; D000539:Alveolar Process / Q000502:physiology; D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry; D001673:Biodegradation, Environmental; D003758:Dental Implantation, Endosseous; D004285:Dogs; D005069:Evaluation Studies as Topic; D016557:Guided Tissue Regeneration, Periodontal / Q000295:instrumentation*; D019344:Lactic Acid / Q000737:chemistry; D008297:Male; D008336:Mandibular Diseases / Q000601:surgery; D008567:Membranes, Artificial; D011098:Polyglactin 910; D011100:Polyglycolic Acid / Q000737:chemistry; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011108:Polymers / Q000737:chemistry; D011138:Polytetrafluoroethylene; D014945:Wound Healing
chemical_list: D001672:Biocompatible Materials; D008567:Membranes, Artificial; D011108:Polymers; C094810:Resolut; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid; D011098:Polyglactin 910; D011138:Polytetrafluoroethylene