Non-insulin dependent diabetes mellitus in a prepubertal child with Prader-Willi syndrome.
Diabetes mellitus has only rarely been reported in prepubertal children with Prader-Willi syndrome. All reported children have required insulin therapy. We report the development of a previously unrecognized association of non-insulin dependent diabetes mellitus in an obese 6 year-old child with Prader-Willi syndrome. She has never developed ketosis or acidosis, and she has been treated with oral hypoglycemic medication.
Sills
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Division of Pediatric Endocrinology, Morristown Memorial Hospital, Atlantic Health Care System, New Jersey 07962, USA.
Rapaport
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D002648:Child; D002872:Chromosome Deletion; D002884:Chromosomes, Human, Pair 15; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D005260:Female; D006801:Humans; D011218:Prader-Willi Syndrome / Q000150:complications* / Q000235:genetics