Paget's disease of the scrotum: a case exhibiting positive prostate-specific antigen staining and associated prostatic adenocarcinoma.
A 75-year-old man with carcinoma of the prostate presented with a pruritic, erythematous plaque involving the scrotal skin. Histological examination revealed extramammary Paget's disease. The intraepidermal tumour cells expressed prostate-specific antigen in keeping with a prostatic origin.
Allan
S J
SJ
Department of Dermatology, Royal Infirmary of Edinburgh NHS Trust, U.K.
McLaren
K
K
Aldridge
R D
RD
D000230:Adenocarcinoma / Q000473:pathology; D000368:Aged; D000951:Antigens, Neoplasm / Q000032:analysis; D005834:Genital Neoplasms, Male / Q000473:pathology*; D006801:Humans; D008297:Male; D016609:Neoplasms, Second Primary / Q000473:pathology*; D010145:Paget Disease, Extramammary / Q000473:pathology*; D017430:Prostate-Specific Antigen / Q000032:analysis*; D011471:Prostatic Neoplasms / Q000473:pathology; D012611:Scrotum
D000951:Antigens, Neoplasm; D017430:Prostate-Specific Antigen