title: Antibiotic sensitivity of endemic Shigella in Mbarara, Uganda.
abstract: We analysed the chimio-sensitivity to antibiotics of endemic strains of Shigella isolated in Mbarara district, southwest Uganda. Twenty four strains were isolated, of which none was sensitive to cotrimoxazole and eight (33.4%, 95% CI [15.6-55.3]) to ampicillin, the two antibiotics recommended to treat dysentery during non epidemic periods in Uganda. Two isolates were resistant to nalidixic acid and none was resistant to the fluoroquinolones (Ciprofloxacin, Norfloxacin). It is concluded that the results of this survey could be used to facilitate the elaboration of a new treatment protocol to treat endemic dysentery cases in Uganda.
authors.affiliation: Epicentre, Kampala, Uganda.
authors.forename: D
authors.initials: D
authors.lastname: Legros
authors.forename: D
authors.initials: D
authors.lastname: Ochola
authors.forename: N
authors.initials: N
authors.lastname: Lwanga
authors.forename: G
authors.initials: G
authors.lastname: Guma
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D004352:Drug Resistance, Microbial; D004405:Dysentery, Bacillary / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology*; D019353:Endemic Diseases / Q000706:statistics & numerical data*; D005243:Feces / Q000382:microbiology; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D014454:Uganda / Q000453:epidemiology
chemical_list: D000900:Anti-Bacterial Agents