title: Recurrent deep venous thrombosis complicating PICC line placement in two patients with cystic fibrosis and activated protein C-resistance.
abstract: Two patients with cystic fibrosis and activated protein C-resistance experienced deep vein thrombosis complicating peripherally inserted central catheter (PICC) use. Cystic fibrosis patients may be at increased risk for catheter rotated thrombosis.
authors.affiliation: Department of Radiology, Columbus Children's Hospital, 700 Children's Drive, Columbus, OH 43205-2696, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Hogan
authors.forename: B D
authors.initials: BD
authors.lastname: Coley
authors.forename: W E
authors.initials: WE
authors.lastname: Shiels
authors.forename: E D
authors.initials: ED
authors.lastname: Allen
authors.forename: K S
authors.initials: KS
authors.lastname: McCoy
mesh_terms: D000293:Adolescent; D000328:Adult; D001132:Arm / Q000098:blood supply; D002406:Catheterization, Peripheral / Q000009:adverse effects*; D003550:Cystic Fibrosis / Q000150:complications / Q000628:therapy*; D005165:Factor V / Q000235:genetics; D005260:Female; D006801:Humans; D011486:Protein C / Q000378:metabolism*; D012008:Recurrence; D013350:Subclavian Vein; D019851:Thrombophilia / Q000150:complications*; D013927:Thrombosis / Q000209:etiology*
chemical_list: D011486:Protein C; C095381:factor V Leiden; D005165:Factor V