title: [Clinical and laboratory study of cefodizime (Modivid) in prophylaxis and treatment of surgical patients].
abstract: The results of the clinical and laboratory study of the efficacy of the prophylactic and therapeutic use of cefodizime (modivid) in patients with chronic calculous cholecystitis and burns are presented. Expediency of the preoperative prophylactic use of the drug and its significance in the treatment of infectious complications of the burn disease were verified. The immunological investigation gave evidence of an increase of the phagocytosis functional activity when cefodizime (modivid) was used prophylactically in cholecystectomy.
authors.affiliation: A.V. Vishnevsky Institute of Surgery, Russian Academy of Medical Sciences, Moscow.
authors.forename: E P
authors.initials: EP
authors.lastname: Khlebnikov
authors.forename: V P
authors.initials: VP
authors.lastname: Iakovlev
authors.forename: L V
authors.initials: LV
authors.lastname: Elagina
authors.forename: V A
authors.initials: VA
authors.lastname: Kubyshkin
authors.forename: M G
authors.initials: MG
authors.lastname: Krutikov
authors.forename: M V
authors.initials: MV
authors.lastname: Pavlova
authors.forename: I A
authors.initials: IA
authors.lastname: Grishina
authors.forename: A A
authors.initials: AA
authors.lastname: Alekseev
authors.forename: A I
authors.initials: AI
authors.lastname: Kurochkina
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019072:Antibiotic Prophylaxis; D000917:Antibody Formation / Q000187:drug effects; D002056:Burns / Q000188:drug therapy* / Q000276:immunology / Q000382:microbiology; D002439:Cefotaxime / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000627:therapeutic use; D018550:Cephalosporin Resistance; D002511:Cephalosporins / Q000008:administration & dosage / Q000627:therapeutic use*; D002764:Cholecystitis / Q000150:complications / Q000276:immunology / Q000601:surgery; D002769:Cholelithiasis / Q000150:complications / Q000276:immunology / Q000601:surgery; D015169:Colony Count, Microbial; D006801:Humans; D007111:Immunity, Cellular / Q000187:drug effects; D008297:Male; D008875:Middle Aged; D013530:Surgical Wound Infection / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control*
chemical_list: D002511:Cephalosporins; D002439:Cefotaxime; C033356:cefodizime
vernacular_title: Kliniko-laboratornaia otsenka tsefodizima (modivida) pri profilakticheskom i lechebnom primenenii v khirurgii.