Eosinophilia in the returning traveler.
Eosinophilia is one of the most common laboratory abnormalities seen in the returning traveler. Although elevations in peripheral eosinophil levels can occur in a wide variety of disease processes, worldwide, helminth parasites are the major group of infectious agents responsible for eosinophilia. While often directed at helminth infections in their early stages of clinical evolution, the approach to the evaluation of the returning traveler with eosinophilia must consider the many causes of eosinophilia including those not casually related to travel. This article reviews the major parasitic causes of eosinophilia and provides a systematic approach to the evaluation of eosinophilia following travel.
Moore
T A
TA
Helminth Immunology Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Nutman
T B
TB
D004802:Eosinophilia / Q000175:diagnosis / Q000209:etiology*; D004804:Eosinophils; D006373:Helminthiasis / Q000150:complications / Q000175:diagnosis; D006801:Humans; D010272:Parasitic Diseases / Q000150:complications / Q000175:diagnosis; D014195:Travel