title: Intraductal carcinoma of the prostate metastatic to the penile urethra: a rare demonstration of two morphologic patterns of tumor growth.
abstract: Penile metastases from prostate cancer are rare and are usually a manifestation of wide-spread cancer dissemination. Isolated urethral metastases form a small fraction of these cases, have a longer survival rate and may represent spread by implantation following instrumentation. We report a case of prostatic carcinoma presenting with an isolated metastasis to the penile urethra after catheterisation and transurethral prostatectomy. The primary tumor had a prominent intraductal component whose architectural features were mimicked in the metastasis. The possible mechanisms of spread and the diverse appearances of cancer associated with an intraductal component are discussed.
authors.affiliation: Department of Pathology, University of Auckland, New Zealand.
authors.forename: G B
authors.initials: GB
authors.lastname: Taylor
authors.forename: J E
authors.initials: JE
authors.lastname: McNeal
authors.forename: R J
authors.initials: RJ
authors.lastname: Cohen
mesh_terms: D000368:Aged; D002277:Carcinoma / Q000737:chemistry / Q000556:secondary*; D006801:Humans; D007150:Immunohistochemistry; D007633:Keratins / Q000032:analysis; D008297:Male; D017430:Prostate-Specific Antigen / Q000032:analysis; D011471:Prostatic Neoplasms / Q000737:chemistry / Q000473:pathology*; D014523:Urethral Neoplasms / Q000737:chemistry / Q000556:secondary*
chemical_list: D007633:Keratins; D017430:Prostate-Specific Antigen