title: Technetium-99m-dimercaptosuccinic acid renal scintigraphy in children over 5 years.
abstract: We retrospectively evaluated the frequency of renal scintigraphic abnormalities in children over 5 years admitted with a first symptomatic urinary tract infection (UTI). Among 261 children investigated, we found only 23 over 5 years having had technetium-99m-dimercaptosuccinic acid scintigraphy during the acute phase of a first UTI. Obvious scintigraphic abnormalities were detected in 14 children (15 kidneys): 12 kidneys showed focal cortical defects and 3 were small and deformed. Ultrasound was normal in 7 of the 15 kidneys with abnormal scintigraphy and in all the kidneys with normal scintigraphy. Among the 12 kidneys with focal cortical lesions, 8 kidneys returned to normal or improved considerably 2-12 months after initial work-up. In conclusion, in children over 5 years admitted with a first symptomatic UTI, the frequency of scintigraphic abnormalities is high and a strategy based only on ultrasound data would miss about 50% of the abnormal kidneys.
authors.affiliation: Department of Pediatrics, A.Z.-V.U.B. Free University, Brussels, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: Vanderfaeillie
authors.forename: P
authors.initials: P
authors.lastname: Flamen
authors.forename: A
authors.initials: A
authors.lastname: Wilikens
authors.forename: B
authors.initials: B
authors.lastname: Desprechins
authors.forename: A
authors.initials: A
authors.lastname: Piepsz
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007668:Kidney / Q000000981:diagnostic imaging* / Q000382:microbiology; D008297:Male; D011877:Radionuclide Imaging; D012189:Retrospective Studies; D019783:Technetium Tc 99m Dimercaptosuccinic Acid; D014552:Urinary Tract Infections / Q000000981:diagnostic imaging*
chemical_list: D019783:Technetium Tc 99m Dimercaptosuccinic Acid