[Localized rhabdomyolysis after anaphylactic shock caused by suxamethonium].
A young woman without remarkable medical history, experienced a life threatening anaphylactoid reaction after induction of general anaesthesia for an emergency curettage. Hypersensitivity reaction involving IgE antibodies against suxamethonium was proven by positive skin test and detection of specific IgE by radio-immuno assay. After intensive therapy for 2 to 3 hours, the patient exhibited rhabdomyolysis localized on both calves. This complication, which required fasciotomies, did not result in renal failure. Local and general outcome was good. Rhabdomyolysis was due to compartmental ischaemia following shock and local external compression in the lithotomy position.
Perret
D
D
Département d'anesthésie-réanimation, CHU de Saint-Etienne, hôpital Nord, Saint-Etienne, France.
Mahul
P
P
Rochette
Y
Y
Auboyer
C
C
D000328:Adult; D000707:Anaphylaxis / Q000150:complications / Q000209:etiology*; D003646:Debridement; D005260:Female; D006801:Humans; D007866:Leg / Q000601:surgery; D009467:Neuromuscular Depolarizing Agents / Q000009:adverse effects*; D012206:Rhabdomyolysis / Q000139:chemically induced* / Q000628:therapy; D012882:Skin Tests; D013390:Succinylcholine / Q000009:adverse effects*
D009467:Neuromuscular Depolarizing Agents; D013390:Succinylcholine
Rhabdomyolyse localisée apés un choc anaphylactique au suxaméthonium.