title: Spanish and African contribution to the genetic pool of the Canary islanders: data from GM and KM haplotypes and RFLPs in the immunoglobulin IGHG loci.
abstract: Data on the GM and KM haplotypes and RFLPs in the immunoglobulin IGHG loci are reported intending to evaluate the genetic contribution of the different populations (Europeans and Africans) who settled Tenerife Island. The GM and KM allotypic systems reveal an estimated European genetic admixture of 88%. The only possible African contribution is the presence of the GM*1,17;...;5* haplotype (2.5%), but no other traces of Black African characteristic haplotypes are found. Although new RFLP haplotypes are described, DNA variation is similar to that reported in Caucasoids with a marked absence of restriction fragments characteristic of Black Africans.
authors.affiliation: Departament de Biologia Animal, Facultat de Biologia, Universitat de Barcelona, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Esteban
authors.forename: J M
authors.initials: JM
authors.lastname: Dugoujon
authors.forename: N
authors.initials: N
authors.lastname: Valveny
authors.forename: E
authors.initials: E
authors.lastname: Gonzalez-Reimers
authors.forename: P
authors.initials: P
authors.lastname: Moral
mesh_terms: D000349:Africa; D001266:Atlantic Islands; D044383:Black People / Q000235:genetics*; D015245:Deoxyribonuclease BamHI; D015252:Deoxyribonucleases, Type II Site-Specific; D005803:Genes, Immunoglobulin; D006239:Haplotypes; D006801:Humans; D007126:Immunoglobulin Allotypes / Q000235:genetics*; D007127:Immunoglobulin Constant Regions / Q000235:genetics; D007129:Immunoglobulin Gm Allotypes / Q000235:genetics; D007143:Immunoglobulin Heavy Chains / Q000235:genetics*; D012150:Polymorphism, Restriction Fragment Length; D013030:Spain / Q000208:ethnology; D044465:White People / Q000235:genetics*
chemical_list: D007126:Immunoglobulin Allotypes; D007127:Immunoglobulin Constant Regions; D007129:Immunoglobulin Gm Allotypes; D007143:Immunoglobulin Heavy Chains; D015245:Deoxyribonuclease BamHI; C024408:endodeoxyribonuclease SacI; D015252:Deoxyribonucleases, Type II Site-Specific; C032823:GGTNACC-specific type II deoxyribonucleases