title: Pleural and bone marrow metastasis from supratentorial oligoastrocytoma grade III.
abstract: We report a 62-year-old man with symptomatic metastasis to the pleural cavity and the bone marrow from a supratentorial oligoastrocytoma grade III, 24 years after the initial symptoms. Before tumor dissemination, the patient underwent brain surgery four times in 5 years. Six months after the last treatment, extraneural dissemination to the right pleural cavity was discovered. Despite resection of the pleural metastasis, local and distant spread to the bone marrow developed. The patient died 5 months after the occurrence of extraneural tumor metastasis. It is speculated that repeated brain surgery and extended survival may promote extraneural dissemination of supratentorial oligoastrocytoma grade III.
authors.affiliation: Ludwig Boltzmann Institute for Research in Epilepsy and Neuromuscular Disorders, Vienna, Austria.
authors.forename: J
authors.initials: J
authors.lastname: Finsterer
authors.forename: S
authors.initials: S
authors.lastname: Breiteneder
authors.forename: M R
authors.initials: MR
authors.lastname: Mueller
authors.forename: C
authors.initials: C
authors.lastname: Wogritsch
authors.forename: M
authors.initials: M
authors.lastname: Vesely
authors.forename: R
authors.initials: R
authors.lastname: Kleinert
authors.forename: G
authors.initials: G
authors.lastname: Pendl
authors.forename: B
authors.initials: B
authors.lastname: Mamoli
mesh_terms: D001254:Astrocytoma / Q000473:pathology / Q000556:secondary*; D019046:Bone Marrow Neoplasms / Q000556:secondary*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010997:Pleural Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D015173:Supratentorial Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D014057:Tomography, X-Ray Computed