Self-organizing molecular networks.
Strong diffusional mixing and short delivery times typical for micrometer and sub-micrometer reaction volumes lead to a special situation where the turnover times of individual enzyme molecules become the largest characteristic time scale of the chemical kinetics. Under these conditions, populations of cross-regulating allosteric enzymes form molecular networks that exhibit various kinds of self-organized coherent collective dynamics.
Stange
P
P
Abteilung Physikalische Chemie, Fritz-Haber-Institut der Max-Planck-Gesellschaft, Berlin, Germany.
Zanette
D
D
Mikhailov
A
A
Hess
B
B
D002468:Cell Physiological Phenomena; D004798:Enzymes / Q000737:chemistry / Q000378:metabolism*; D007700:Kinetics; D008432:Mathematical Computing; D009415:Nerve Net; D013816:Thermodynamics
D004798:Enzymes