Mononucleosis syndrome and coincidental human herpesvirus-7 and Epstein-Barr virus infection.
Two girls (a 5 year old and a 21 month old) experiencing mononucleosis syndrome with coincidental human herpesvirus (HHV)-7 and Epstein-Barr virus (EBV) infections are described. One patient had primary HHV-7 infection and reactivated EBV infection. The other had primary HHV-7 and EBV infections. These cases indicated that HHV-7 is capable of inducing infectious mononucleosis-like illness. Multiple herpesvirus infection in one of the patients also suggests that interaction among herpesviruses can occur in vivo. The consequence of this interaction may have clinical implications.
Chiu
H H
HH
Department of Pediatrics, National Taiwan University Hospital, Taipei, Republic of China.
Lee
C Y
CY
Lee
P I
PI
Lin
K H
KH
Huang
L M
LM
D002675:Child, Preschool; D005260:Female; D006566:Herpesviridae Infections / Q000150:complications; D004854:Herpesvirus 4, Human / Q000254:growth & development; D016199:Herpesvirus 7, Human; D006801:Humans; D007223:Infant; D007244:Infectious Mononucleosis / Q000821:virology*; D014775:Virus Activation