[Personal experience with diagnosis of complete hydatidiform mole based on DNA].
In our study we analyzed 13 cases of histologically defined complete hydatidiform mole (CHM), by using cytogenetic and molecular genetic methods. There were seven homozygous and six heterozygous CHM. In one case of heterozygous CHM we found a biparental contribution to genomic DNA. This is evidence of a more heterogeneous etiopathogenesis of hydatidiform mole.
Repiská
V
V
Ustav lekárskej biológie, Bratislava.
Vojtassák
J
J
Korbel
M
M
Danihel
L
L
Zajac
V
V
D004273:DNA, Neoplasm / Q000235:genetics*; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000175:diagnosis* / Q000235:genetics; D007621:Karyotyping; D012150:Polymorphism, Restriction Fragment Length; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000235:genetics
D004273:DNA, Neoplasm
Nase skúsenosti s diagnostikou kompletnej moly hydatidózy na úrovni DNA.