CPT (8-cyclopentyl theophylline) corrects CFTR antibody inhibited mucin secretion.
Pereira
M M
MM
Department of Medical Biochemistry, University of Wales College of Medicine, Cardiff, U.K.
Dormer
R L
RL
McPherson
M A
MA
D000318:Adrenergic beta-Agonists / Q000494:pharmacology; D000818:Animals; D000906:Antibodies / Q000276:immunology*; D002478:Cells, Cultured; D000242:Cyclic AMP / Q000378:metabolism; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000235:genetics / Q000276:immunology*; D007545:Isoproterenol / Q000494:pharmacology; D009077:Mucins / Q000378:metabolism*; D058915:Purinergic P1 Receptor Antagonists; D051381:Rats; D013363:Submandibular Gland / Q000187:drug effects / Q000378:metabolism; D013805:Theobromine / Q000031:analogs & derivatives / Q000494:pharmacology; D013806:Theophylline / Q000031:analogs & derivatives* / Q000494:pharmacology
D000318:Adrenergic beta-Agonists; D000906:Antibodies; D009077:Mucins; D058915:Purinergic P1 Receptor Antagonists; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; C053907:8-cyclopentyl-1,3-dimethylxanthine; C057837:3,7-dimethyl-1-propargylxanthine; D013806:Theophylline; D000242:Cyclic AMP; D007545:Isoproterenol; D013805:Theobromine