Olfactory G proteins: simple and complex signal transduction.
In both vertebrates and invertebrates, olfactory perception is mediated by G-protein-coupled receptors. Recent work, in both mouse and Caenorhabditis elegans, sheds light on the role of specific G proteins in olfactory signal transduction, neuronal morphology and axon guidance.
Ebrahimi
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FA
Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, USA.
Chess
A
A
D000818:Animals; D001369:Axons / Q000502:physiology; D017173:Caenorhabditis elegans / Q000235:genetics; D029742:Caenorhabditis elegans Proteins; D044385:GTP-Binding Protein alpha Subunits; D019206:GTP-Binding Protein alpha Subunits, Gi-Go; D019204:GTP-Binding Proteins / Q000235:genetics / Q000502:physiology*; D015801:Helminth Proteins / Q000235:genetics / Q000502:physiology*; D020962:Heterotrimeric GTP-Binding Proteins; D006801:Humans; D051379:Mice; D009024:Morphogenesis; D016296:Mutagenesis; D009833:Olfactory Pathways / Q000502:physiology*; D018035:Receptors, Odorant / Q000235:genetics / Q000502:physiology*; D015398:Signal Transduction
D029742:Caenorhabditis elegans Proteins; D044385:GTP-Binding Protein alpha Subunits; D015801:Helminth Proteins; D018035:Receptors, Odorant; C110666:odr-3 protein, C elegans; C084618:olfactory G protein subunit alpha olf; D019204:GTP-Binding Proteins; D019206:GTP-Binding Protein alpha Subunits, Gi-Go; D020962:Heterotrimeric GTP-Binding Proteins