Congenital insensitivity to pain with anhidrosis. A case report.
We present a five-year-old girl with congenital insensitivity to pain with anhidrosis. A skeletal radiographic survey revealed several old fractures. Application of pilocarpine showed anhidrosis and nerve biopsy revealed a significant decrease in the number of myelinated and unmyelinated nerve fibres.
Herdem
M
M
Department of Orthopaedics and Traumatology, Faculty of Medicine, University of Cukurova, Adana, Turkey.
Polat
S
S
Ozbarlas
S
S
Onaç
E
E
D002675:Child, Preschool; D005260:Female; D050723:Fractures, Bone / Q000000981:diagnostic imaging / Q000209:etiology; D006801:Humans; D007007:Hypohidrosis / Q000150:complications*; D009412:Nerve Fibers / Q000473:pathology / Q000648:ultrastructure; D010019:Osteomyelitis / Q000000981:diagnostic imaging / Q000209:etiology; D000699:Pain Insensitivity, Congenital / Q000150:complications* / Q000473:pathology; D011859:Radiography; D014457:Ulna / Q000000981:diagnostic imaging