title: Development of a macromolecular prodrug of FK 506: III: In vivo disposition of FK 506-dextran conjugate.
authors.affiliation: Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Yoshimura
authors.forename: H
authors.initials: H
authors.lastname: Yura
authors.forename: T
authors.initials: T
authors.lastname: Hamashima
authors.forename: T
authors.initials: T
authors.lastname: Oka
authors.forename: Y
authors.initials: Y
authors.lastname: Takakura
authors.forename: M
authors.initials: M
authors.lastname: Hadhida
mesh_terms: D000818:Animals; D003911:Dextrans / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics; D007275:Injections, Intravenous; D008297:Male; D008657:Metabolic Clearance Rate; D011355:Prodrugs / Q000008:administration & dosage / Q000493:pharmacokinetics*; D051381:Rats; D011917:Rats, Inbred Lew; D016559:Tacrolimus / Q000008:administration & dosage / Q000097:blood / Q000493:pharmacokinetics*; D014018:Tissue Distribution
chemical_list: D003911:Dextrans; C112843:FK 506-dextran conjugate; D007166:Immunosuppressive Agents; D011355:Prodrugs; D016559:Tacrolimus