[Dynamic changes in soluble interleukin-2 receptor levels after rat corneal allograft].
OBJECTIVE
To evaluate the diagnostic utility of serum IL-2R level test in corneal allograft rejection.


METHODS
Serum soluble IL-2R was detected by radioimmunoassay in rat corneal allograft model.


RESULTS
Levels of soluble IL-2R were markedly elevated prior to the clinical diagnosis of rejection.


CONCLUSIONS
Marked elevations of soluble IL-2R are associated with rejection, measurement of soluble IL-2R may have a useful value in the early diagnosis of corneal allograft rejection.
Li
Z
Z
Department of Ophthalmology, Jinan University, Guangzhou, China.
Li
C
C
Shen
J
J
Xu
J
J
D000818:Animals; D003315:Cornea / Q000473:pathology*; D006084:Graft Rejection; D015948:Keratoplasty, Penetrating; D051381:Rats; D011917:Rats, Inbred Lew; D015375:Receptors, Interleukin-2 / Q000097:blood*; D014184:Transplantation, Homologous; D014185:Transplantation, Isogeneic
D015375:Receptors, Interleukin-2