Mollenines A and B: new dioxomorpholines from the ascostromata of Eupenicillium molle.
Two new dioxomorpholines (1 and 2) have been isolated from the sclerotioid ascostromata of Eupenicillium molle (NRRL 13062). Their structures were determined by analysis of NMR data. Mollenine A (1) exhibited moderate cytotoxicity and antibacterial activity, but neither compound displayed significant antiinsectan activity.
Wang
H j
Hj
Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA.
Gloer
J B
JB
Wicklow
D T
DT
Dowd
P F
PF
D000900:Anti-Bacterial Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001203:Ascomycota / Q000737:chemistry / Q000378:metabolism*; D007306:Insecticides / Q000633:toxicity; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D008968:Molecular Conformation; D009025:Morpholines / Q000302:isolation & purification / Q000494:pharmacology; D012988:Soil Microbiology; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000900:Anti-Bacterial Agents; D007306:Insecticides; D009025:Morpholines; C113219:mollenine A; C113220:mollenine B