title: [Intra-arterial antiblastic treatment of breast carcinoma].
abstract: OBJECTIVE
  To report our personal experience with the locoregional treatment of breast cancer.
  
  
  METHODS
  Eighteen patients aged 33-67 years (mean: 54 years) were treated with 31 sessions of intra-arterial antiblastic infusion, 5 of them for neoadjuvant purposes (Group 1), 5 for palliation in unresectable tumors (Group 2) and 8 for cutaneous recurrences after mastectomy (Group 3).
  
  
  RESULTS
  2/5 CR and 3/5 PR were obtained in Group 1; 2/5 lesions were made resectable and 3/5 RP obtained in stage III or unresectable lesions (Group 2). Finally, 3/8 CR, 3/8 PR, 1/8 SD and 1/8 PD were observed in Group 3. An objective response according to WHO criteria was demonstrated in 15/18 cases (88%). We had no post-treatment hematologic complications, but one patient presented focal subcutaneous sclerosis and one cutaneous necrosis.
  
  
  CONCLUSIONS
  The morphological efficacy of intraarterial antiblastic infusion in our series was similar to that of other series. No definitive conclusions can be drawn yet about clinical results and long-term survival. This poorly invasive and low risk procedure, which should be combined with other treatments, permits to reduce the extent of surgery and to treat skin recurrences.
authors.affiliation: Servizio di Radiologia Diagnostica, Ospedale Bellaria C. A. Pizzardi, Bologna.
authors.forename: R
authors.initials: R
authors.lastname: Roversi
authors.forename: G
authors.initials: G
authors.lastname: Rossi
authors.forename: S
authors.initials: S
authors.lastname: Ricci
authors.forename: M
authors.initials: M
authors.lastname: Roversi
authors.forename: G
authors.initials: G
authors.lastname: Pinelli
authors.forename: G
authors.initials: G
authors.lastname: Cavallo
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007261:Infusions, Intra-Arterial; D008875:Middle Aged
chemical_list: D000970:Antineoplastic Agents
vernacular_title: Terapia antiblastica per via intrarteriosa del carcinoma della mammella.