SMC protein complexes and higher-order chromosome dynamics.
The structural maintenance of chromosome (SMC) family of proteins represents an expanding group of chromosomal ATPases that are highly conserved among Bacteria, Archaea and Eukarya. During the past year, significant progress has been made towards understanding the cellular functions and molecular activities of this new class of proteins. Emerging evidence suggests that eukaryotic SMC proteins form large protein complexes with non-SMC subunits and act as key components for a wide variety of higher-order chromosome dynamics.
Hirano
T
T
Cold Spring Harbor Laboratory, New York, USA. hirano@cshl.org
D000818:Animals; D002868:Chromosomal Proteins, Non-Histone; D002875:Chromosomes / Q000737:chemistry*; D019143:Evolution, Molecular; D006801:Humans
D002868:Chromosomal Proteins, Non-Histone