title: The lesions of the pterygopalatine and infratemporal spaces: Computed tomography evaluation.
abstract: OBJECTIVE
  The purpose of this study was to categorize the computed tomography features of lesions affecting the pterygopalatine fossa and infratemporal fossa and thus aid in the diagnosis of these lesions.
  
  
  METHODS
  Eighty-six patients with lesions of the pterygopalatine fossa and infratemporal fossa were examined with computed tomography; the lesions were confirmed by both surgery and biopsy. The patients were divided into three groups: group I consisted of patients in whom the lesions had originated in one or both fossae; group II, of patients in whom the lesions originated in other oral and maxillofacial regions but showed extension into the pterygopalatine and infratemporal fossae; and group III, of patients in whom the lesions had multicentric origins.
  
  
  RESULTS
  Of the 11 cases in group I, demarcation was confined to both fossae in 4 patients, and involvement of the adjacent structures was shown on computed tomography images in 7 patients. Involved structures included the maxillary sinus (4 sides), nasal cavity (3 sides), mandibular ramus (6 sides), buccal space (2 sides), base of the skull (5 sides), palate (3 sides), and parapharyngeal space (5 sides). In the 70 cases in group II, computed tomography images showed that lesions had invaded both fossae via following routes: (1) 40 lesions in the maxillary sinus had infiltrated posterolaterally into 26 pterygopalatine and 39 infratemporal fossae; (2) two nasal cavity and three nasopharynx tumors had infiltrated laterally or lateroanteriorly into five pterygopalatine and one infratemporal fossae; (3) lesions originating in mandibular rami (9 lesions), buccal regions (4 lesions), parapharyngeal spaces (1 lesion) and parotid glands (1 lesion) had intruded medially into 15 infratemporal fossae; (4) two temporal bone tumors had encroached inferiorly on two infratemporal fossae; (5) four palate tumors had led to involvement of three pterygopalatine and four infratemporal fossae; and (6) four inflammatory diseases of the facial spaces involved two pterygopalatine and four infratemporal fossae. Group III lesions (5 cases) affecting one pterygopalatine and five infratemporal fossae were hemangiomas; one was a malignant lymphoma.
  
  
  CONCLUSIONS
  Group I lesions may involve the adjacent anatomic structures of both pterygopalatine and infratemporal fossae in every direction. Group II lesions that correspond to the various origins of the maxillofacial region have different pathways of infiltration into the pterygopalatine or infratemporal fossae. Computed tomography examination is very important in the evaluation of lesions involving the pterygopalatine and infratemporal fossae.
authors.affiliation: Department of Radiology, Ninth People's Hospital, School of Stomatology, Shanghai Second Medical University, People's Republic of China.
authors.forename: Q
authors.initials: Q
authors.lastname: Yu
authors.forename: P
authors.initials: P
authors.lastname: Wang
authors.forename: H
authors.initials: H
authors.lastname: Shi
authors.forename: J
authors.initials: J
authors.lastname: Luo
authors.forename: D
authors.initials: D
authors.lastname: Sun
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D014057:Tomography, X-Ray Computed