title: Obstruction of the renal pelvis due to an insoluble blood clot after epsilon-aminocaproic acid therapy: resolution with intraureteral streptokinase instillations.
abstract: OBJECTIVE
  We demonstrate the effectiveness of intraureteral streptokinase instillations for the resolution of an insoluble blood clot in the renal pelvis.
  
  
  METHODS
  A patient with renal adenocarcinoma had prolonged hematuria related to involvement of the "pyelum" by the tumor. An insoluble blood clot obstruction of the left renal collecting system developed as a consequence of epsilon aminocaproic acid therapy, which was treated with low dose streptokinase through a ureteral catheter.
  
  
  RESULTS
  Complete resolution of the clot and obstruction occurred within 3 days of therapy.
  
  
  CONCLUSIONS
  This relatively simple approach should be used for the treatment of obstruction before radical surgery is performed.
authors.affiliation: Department of Urology, Nij Smellinghe Hospital, Drachten, The Netherlands.
authors.forename: L F
authors.initials: LF
authors.lastname: Wymenga
authors.forename: W J
authors.initials: WJ
authors.lastname: van der Boon
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015119:Aminocaproic Acid / Q000009:adverse effects*; D000933:Antifibrinolytic Agents / Q000009:adverse effects*; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D007322:Instillation, Drug; D007674:Kidney Diseases / Q000209:etiology; D007682:Kidney Pelvis; D013300:Streptokinase / Q000008:administration & dosage*; D013927:Thrombosis / Q000139:chemically induced* / Q000150:complications / Q000188:drug therapy*
chemical_list: D000933:Antifibrinolytic Agents; D005343:Fibrinolytic Agents; D013300:Streptokinase; D015119:Aminocaproic Acid