title: Toxoplasmic retinochoroiditis: resolution without treatment of the perilesional satellite dark dots seen by indocyanine green angiography.
abstract: OBJECTIVE
  Satellite dark dots (SDD) seen by indocyanine green angiography (ICGA) around the main retinochoroiditis focus are described in 75% of cases. Whether SDDs represent subclinical infectious foci or just a perilesional inflammatory reaction is not known. The purpose here was to report a case giving additional information on this question.
  
  
  METHODS
  We analysed the evolution of ICGA SDDs in a patient with recurrent toxoplasmic retinochoroiditis who received no antitoxoplasmic treatment because the lesion was located outside the areas where treatment is classically recommended.
  
  
  RESULTS
  The patient had a recurrence of retinochoroiditis on the nasal aspect of the disc about 2 disc diameters away from the disc. It was decided to observe the recurrence before introducing treatment. Diminution of SDDs occurred by 3 weeks after the initial ICGA, and complete resolution was observed on a follow-up ICG angiogram obtained 8 weeks after the initial visit.
  
  
  CONCLUSIONS
  Resolution of ICGA SDDs in toxoplasmic retinochoroiditis seems to occurring a similar fashion whether or not the retinochoroiditis is treated by anti-toxoplasmic drugs, indicating that SDDs probably represent a non-infectious perilesional inflammatory reaction.
authors.affiliation: Department of Ophthalmology, Hôpital Jules Gonin, University of Lausanne, Switzerland.
authors.forename: Y
authors.initials: Y
authors.lastname: Guex-Crosier
authors.forename: C
authors.initials: C
authors.lastname: Auer
authors.forename: O
authors.initials: O
authors.lastname: Bernasconi
authors.forename: C P
authors.initials: CP
authors.lastname: Herbort
mesh_terms: D000208:Acute Disease; D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis; D002825:Chorioretinitis / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D002829:Choroid / Q000473:pathology; D004396:Coloring Agents; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D012008:Recurrence; D012075:Remission, Spontaneous; D012160:Retina / Q000473:pathology; D014122:Toxoplasma / Q000276:immunology; D014126:Toxoplasmosis, Ocular / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology*
chemical_list: D000913:Antibodies, Protozoan; D004396:Coloring Agents; D007208:Indocyanine Green