Long-term particulate and other air pollutants and lung function in nonsmokers.
The associations between lung function measures (spirometry and peak expiratory flow lability) and estimated 20-yr ambient concentrations of respirable particles, suspended sulfates, sulfur dioxide, ozone, and indoor particles were studied in a sample of 1,391 nonsmokers followed since 1977. Differences in air pollutants across the population were associated with decrements of lung function. An increase of 54 d/yr when particles < 10 micro(m) in diameter (PM10) exceeded 100 microg/m3 was associated with a 7.2% decrement in FEV1, as percent of predicted, in males whose parents had asthma, bronchitis, emphysema, or hay fever and with increased peak expiratory flow lability of 0.8% for all females and 0.6% for all males. An increase in mean SO4 concentration of 1.6 microg/m3 was associated with a 1.5% decrement in FEV1, as percent of predicted, in all males. An increase of 23 ppb of ozone as an 8-h average was associated with a 6.3% decrement in FEV1, as percent of predicted, in males whose parents had asthma, bronchitis, emphysema, or hay fever.
Abbey
D E
DE
Loma Linda University, School of Public Health, Loma Linda, California, USA. dAbbey@sph.llu.edu
Burchette
R J
RJ
Knutsen
S F
SF
McDonnell
W F
WF
Lebowitz
M D
MD
Enright
P L
PL
D000328:Adult; D000388:Air / Q000032:analysis; D000393:Air Pollutants; D015331:Cohort Studies; D005260:Female; D006801:Humans; D016014:Linear Models; D008168:Lung / Q000502:physiology*; D008297:Male; D010126:Ozone / Q000032:analysis; D010316:Particle Size; D010366:Peak Expiratory Flow Rate; D013431:Sulfates / Q000032:analysis; D013458:Sulfur Dioxide / Q000032:analysis; D014028:Tobacco Smoke Pollution
D000393:Air Pollutants; D013431:Sulfates; D014028:Tobacco Smoke Pollution; D013458:Sulfur Dioxide; D010126:Ozone