title: [Perforating necrobiosis lipoidica: 2 cases].
abstract: BACKGROUND
  Perforating necrobiosis lipoidica is a rare clinical form of necrobiosis lipoidica and is almost always associated with diabetes. Necrotized tissue is usually eliminated via transfollicular perforations.
  
  
  METHODS
  We report two cases of perforating necrobiosis lipoidica associated with type II diabetes mellitus. The characteristic clinical feature was the presence of keratotic plugs around the periphery of the lesions. Transfollicular perforation predominated in the first case. The second also presented epidermal perforation.
  
  
  CONCLUSIONS
  There have been only 6 cases of perforating necrobiosis lipoidica in the literature. To our knowledge, this is the first case report of transepidermal elimination. We confirmed the constant association between this perforation type and diabetes mellitus.
authors.affiliation: Service de Dermatologie, Hôpital des maladies cutanées et venériennes, Thessaloniki, Grèce.
authors.forename: I
authors.initials: I
authors.lastname: Lefaki
authors.forename: G
authors.initials: G
authors.lastname: Vakali
authors.forename: O
authors.initials: O
authors.lastname: Mourelou
authors.forename: M
authors.initials: M
authors.lastname: Stefanidou
authors.forename: E
authors.initials: E
authors.lastname: Kapetis
mesh_terms: D003920:Diabetes Mellitus / Q000473:pathology; D005260:Female; D006229:Hand Dermatoses / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007868:Leg Dermatoses / Q000175:diagnosis* / Q000628:therapy; D008875:Middle Aged; D009335:Necrobiosis Lipoidica / Q000175:diagnosis* / Q000628:therapy
vernacular_title: Nécrobiose lipoïdique perforante: deux observations.