title: [Acute ventricular septal perforation in a patient with autoimmune hemolytic anemia].
abstract: A 71-year-old woman with autoimmune hemolytic anemia underwent an emergency endocardial patch repair for ventricular septal perforation after acute myocardial infarction. Use of washed red blood cells was effective in averting hemolytic crisis throughout perioperative period. In spite of improvement of her hemodynamics, liver dysfunction which had been present preoperatively deteriorated after the operation. Finally she died of hepatic failure on the 21st postoperative day. Deterioration of liver function could not be associated with autoimmune hemolytic anemia. To date, little information is available concerning the influence of cardiopulmonary bypass on hemolysis in patients with autoimmune hemolytic anemia. Therefore, prudent management and use of washed red blood cells transfusion would prevent hemolytic aggravation even in open heart surgery.
authors.affiliation: Department of Cardiovascular Surgery, Miyazaki Prefectural Hospital, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Matsumoto
authors.forename: T
authors.initials: T
authors.lastname: Yuda
authors.forename: T
authors.initials: T
authors.lastname: Ueno
authors.forename: A
authors.initials: A
authors.lastname: Taira
mesh_terms: D000208:Acute Disease; D000368:Aged; D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications*; D006348:Cardiac Surgical Procedures / Q000379:methods; D004630:Emergencies; D005260:Female; D006801:Humans; D018658:Ventricular Septal Rupture / Q000150:complications / Q000601:surgery*