title: Serum zinc and copper concentrations and Cu/Zn ratios in patients with hepatopathies or diabetes.
abstract: The serum zinc and copper levels, as well as Zn/Cu ratios, were determined in 30 patients (18 with diabetes and 12 with hepatopathies) and compared to healthy-age matched controls by atomic absorption spectrometry. Serum Zn (0.946 +/- 0.302 mg/l) and Cu (0.952 +/- 0.355 mg/l) concentrations were not significantly different in patients with hepatopathies as compared to controls (p > 0.05). Serum Zn concentrations (0.778 +/- 0.164 mg/l) were significantly lower in diabetic patients than those determined in controls (p < 0.01). In contrast, Cu levels (0.987 +/- 0.305 mg/l) were not significantly different (p > 0.05) than in controls. Serum Cu/Zn ratios were not significantly different in patients with diabetes or hepatopathies than those measured in healthy controls (p > 0.05). In patients, no statistically significant differences were observed in the Zn, Cu and Cu/Zn with respect to sex (p > 0.05) or age (p > 0.05).
authors.affiliation: Department of Nutrition and Bromatology, Faculty of Pharmacy, University of Granada, Spain.
authors.forename: C
authors.initials: C
authors.lastname: Terrés-Martos
authors.forename: M
authors.initials: M
authors.lastname: Navarro-Alarcón
authors.forename: F
authors.initials: F
authors.lastname: Martín-Lagos
authors.forename: H
authors.initials: H
authors.lastname: López-G de la Serrana
authors.forename: V
authors.initials: V
authors.lastname: Pérez-Valero
authors.forename: M C
authors.initials: MC
authors.lastname: López-Martínez
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003300:Copper / Q000097:blood*; D003430:Cross-Sectional Studies; D003922:Diabetes Mellitus, Type 1 / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D005260:Female; D006509:Hepatitis B / Q000097:blood*; D006526:Hepatitis C / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D015032:Zinc / Q000097:blood*
chemical_list: D003300:Copper; D015032:Zinc