[The Philadelphia chromosome: from the gene to therapeutic methods].
Pérez-Losada
J
J
Departamento de Proliferación y Diferenciación, CSIC, Universidad de Salamanca.
González-Sarmiento
R
R
Sánchez-García
I
I
D017209:Apoptosis / Q000502:physiology; D002455:Cell Division / Q000502:physiology; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D002892:Chromosomes, Human, Pair 22 / Q000235:genetics; D002899:Chromosomes, Human, Pair 9 / Q000235:genetics; D004273:DNA, Neoplasm / Q000235:genetics; D016044:Fusion Proteins, bcr-abl / Q000737:chemistry / Q000235:genetics* / Q000502:physiology; D015973:Gene Expression Regulation, Leukemic; D016313:Genes, abl; D015316:Genetic Therapy; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000378:metabolism; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics* / Q000628:therapy; D014411:Neoplastic Stem Cells / Q000378:metabolism / Q000473:pathology; D010677:Philadelphia Chromosome; D010766:Phosphorylation; D011499:Protein Processing, Post-Translational; D011505:Protein-Tyrosine Kinases / Q000737:chemistry / Q000502:physiology; D011518:Proto-Oncogene Proteins / Q000737:chemistry / Q000502:physiology; D016315:Proto-Oncogene Proteins c-abl / Q000737:chemistry / Q000502:physiology; D051562:Proto-Oncogene Proteins c-bcr
D004273:DNA, Neoplasm; D011518:Proto-Oncogene Proteins; D011505:Protein-Tyrosine Kinases; D016044:Fusion Proteins, bcr-abl; D016315:Proto-Oncogene Proteins c-abl; C496613:BCR protein, human; D051562:Proto-Oncogene Proteins c-bcr
El cromosoma Filadelfia: desde el gen hacia mecanismos terapéuticos.