Clinical regeneration with guided tissue barriers.
This review of the current periodontal literature evaluates clinical regeneration with guided tissue barriers in infrabony defects and furcations. A meta-analysis was conducted by calculating weighted means with confidence intervals for each treatment group. Clinical improvement in infrabony defects was best for polylactic acid/polyglactin (PLA/PGA) barriers, with a mean pocket reduction of 5.3 mm and a mean gain in clinical probing attachment level of 4.7 mm. For furcations, special attention was given to the frequency of either complete or partial (> or = 50%) furcation closure. Complete furcation closure was an infrequent result of guided tissue regeneration, occurring in only 7% to 19% of furcations treated with barriers. For the time period reported, the best clinical results in furcations and infrabony defects occurred with PLA/PGA-type barriers. However, there were no statistically significant differences among the various barriers in infrabony defects or furcations.
Evans
G H
GH
Louisiana State University, School of Dentistry, New Orleans 70119, USA.
Yukna
R A
RA
Cambre
K M
KM
Gardiner
D L
DL
D016301:Alveolar Bone Loss / Q000601:surgery*; D003094:Collagen; D017823:Furcation Defects / Q000601:surgery*; D016557:Guided Tissue Regeneration, Periodontal / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D019344:Lactic Acid; D007840:Latex; D008567:Membranes, Artificial; D011091:Polyesters; D011108:Polymers; D011138:Polytetrafluoroethylene
D007840:Latex; D008567:Membranes, Artificial; D011091:Polyesters; D011108:Polymers; D019344:Lactic Acid; C033616:poly(lactide); D011138:Polytetrafluoroethylene; D003094:Collagen