title: A study of allergy to penicillin antibiotics in 1995 in the Child Allergy Department of the Gregorio Marañón University hospital.
abstract: We present 219 cases of adverse reactions to penicillin and related antibiotics during 1995 in the Child Allergy Department of Gregorio Marañón University Hospital. Amoxicillin was the most frequent cause of the reaction. The most common clinical symptom was urticaria followed by angio-edema and other characteristic exanthemas. A diagnosis of allergy to penicillin and related drugs was only made in 20 cases in which the predominant symptomatology was urticaria and the antibiotic most commonly involved was again amoxicillin. Diagnosis was confirmed by a skin test, specific IgE determination and controlled provocation. In 3 of the 20 cases diagnosis was made in the reassessment or second study, which was carried out in all cases in which more than one year had passed between the reaction and the initial allergological study.
authors.affiliation: Child Allergy Department of Gregorio Marañón University Hospital, Madrid, España.
authors.forename: M A
authors.initials: MA
authors.lastname: Mínguez
authors.forename: L
authors.initials: L
authors.lastname: Zapatero
authors.forename: M
authors.initials: M
authors.lastname: Caloto
authors.forename: M I
authors.initials: MI
authors.lastname: Martínez-Molero
mesh_terms: D002648:Child; D004342:Drug Hypersensitivity / Q000175:diagnosis* / Q000209:etiology; D006748:Hospital Departments; D006801:Humans; D010406:Penicillins / Q000009:adverse effects*; D013030:Spain
chemical_list: D010406:Penicillins