[Pyelocaliceal urothelial carcinoma associated with pelvis lithiasis].
OBJECTIVE
Epithelial neoplasms of the upper collecting system account for less than 5 percent of all urothelial tumors and they are not histologically unlike those of the bladder. We report a case of pelviocaliceal urothelial carcinoma associated with a calculus in the renal pelvis.


METHODS
A 75-year-old man who presented with hematuria, fever and flank pain is described. The US and CT findings disclosed a calculus in the left renal pelvis and hydronephrosis nephrectomy was performed.


RESULTS
The pathological analysis revealed a pelviocaliceal urothelial carcinoma on an underlying stone and overexpression of the p53 protein.


CONCLUSIONS
Diagnostic imaging techniques may fail to detect tumors of the renal pelvis with a large underlying stone. The overexpression of the p53 protein may be involved in the malignant transformation of the urothelial cells.
Medina Pérez
M
M
Servicio de Anatomía Patológica, Hospital de La Merced, Sevilla, España.
Valpuesta Fernández
I
I
Valero Puerta
J
J
D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000150:complications* / Q000473:pathology; D006801:Humans; D007669:Kidney Calculi / Q000150:complications* / Q000473:pathology; D007680:Kidney Neoplasms / Q000150:complications* / Q000473:pathology; D007682:Kidney Pelvis / Q000473:pathology; D008297:Male
Carcinoma urotelial pielocalicial asociado a litiasis piélica.