title: Body mass predicts the survival of patients with new International Federation of Gynecology and Obstetrics Stage IB1 and IB2 cervical carcinoma treated with radical hysterectomy.
abstract: BACKGROUND
  The authors evaluated the impact of body mass on survival and morbidity of patients with new International Federation of Gynecology and Obstetrics (FIGO) Stage IB1 and IB2 cervical carcinoma managed with radical hysterectomy.
  
  
  METHODS
  Two hundred twenty-nine patients with Stage IB1 or IB2 cervical carcinoma treated with radical hysterectomy were studied in a multivariate logistic regression analysis. The body mass index (BMI) and the ponderal index (PI) were used as measures of body mass and were analyzed as predictors of recurrence, survival, and complications in light of the new staging system.
  
  
  RESULTS
  Twenty-seven of 229 patients died of recurrent disease. A low BMI or a high PI were predictive of poor survival. Tumor greatest dimension, lymph node involvement, BMI, and PI were all independent predictors of survival (P=0.0006). The only independent predictor of complications was para-aortic lymph node dissection (P=0.0026).
  
  
  CONCLUSIONS
  Cervical carcinoma patients with a low body mass, as indicated by a low BMI or a high PI, were found to have poor survival after undergoing radical hysterectomy. Additional predictors of poor survival included lymph node metastases and increased tumor size. BMI and PI are more important predictors of survival than the new FIGO Stages IB1 and IB2. Body mass is not predictive of complications.
authors.affiliation: Department of Obstetrics and Gynecology, Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans, Louisiana 70121, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Finan
authors.forename: M S
authors.initials: MS
authors.lastname: Hoffman
authors.forename: R
authors.initials: R
authors.lastname: Chambers
authors.forename: J V
authors.initials: JV
authors.lastname: Fiorica
authors.forename: S
authors.initials: S
authors.lastname: DeCesare
authors.forename: R C
authors.initials: RC
authors.lastname: Kline
authors.forename: W S
authors.initials: WS
authors.lastname: Roberts
authors.forename: D
authors.initials: D
authors.lastname: Cavanagh
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D005260:Female; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000401:mortality / Q000601:surgery*