title: [Allo-transfusion saving measures in maxillofacial surgery].
abstract: In terms of a prospective clinical study between June 1994 and May 1996, in 204 patients undergoing maxillo-facial surgeries with a expected blood loss of more than 500 ml a protocol of bloodsaving measures was followed. By means of an additional retrospective study, the consumption of homologous blood and the amount of bloodsaving measures between June 1990 and May 1994 was evaluated. Bloodsaving measures were consisting from acute normovolemic hemodilution, controlled moderate hypotension, cell saving, preoperative autologous blood donation, and administration of rh-erythropoetine. The methoda were applied isolated as well as in combination. Special concerns were given to a stable intraoperative homeostasis and to the acceptance of a low hematocrit perioperatively. Aim of the study was to investigate if, following the protocol, even in major maxillofacial procedures homologous blood transfusions almost completely can be avoided. Out of the 204 patients in the prospective study, only 30 received homologous blood. For the period June 94 to May 96, the reduction of the number of patients receiving homologous blood in relation to the period June 90 to May 94 was 83%. The results indicate that in the years 94 to 96 twice as much patients received bloodsaving measures. These led to a reduction of homologous blood consumption for 427 units in 1990 to 56 units 1996 (p < 0.001). If three measures, i.e. normovolemic hemodilution, cell saving, and hypotension were combined, the need of blood transfusion was at the minimum level. The effective reduction of homologous blood transfusion by consequent application of bloodsaving measures can with these data obviously be demonstrated.
authors.affiliation: Klinik und Poliklinik für Kiefer- und Gesichtschirurgie, Universitätsspital Zürich.
authors.forename: R G
authors.initials: RG
authors.lastname: Rohling
authors.forename: A P
authors.initials: AP
authors.lastname: Zimmermann
authors.forename: P E
authors.initials: PE
authors.lastname: Haers
authors.forename: M C
authors.initials: MC
authors.lastname: Locher
authors.forename: A
authors.initials: A
authors.lastname: Major
authors.forename: H F
authors.initials: HF
authors.lastname: Sailer
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016063:Blood Loss, Surgical / Q000503:physiopathology; D001804:Blood Transfusion, Autologous; D001810:Blood Volume / Q000502:physiology; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D006400:Hematocrit; D006438:Hemodilution; D006487:Hemostasis / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012189:Retrospective Studies; D013515:Surgery, Oral
vernacular_title: Fremdblutsparende Massnahmen in der Kiefer-und Gesichtschirurgie.