title: Finding evidence to support airway clearance techniques in cystic fibrosis.
abstract: Chest physiotherapy, aiming to clear bronchopulmonary secretions, has become a mainstay in the respiratory management of cystic fibrosis (CF). Early diagnosis and new therapeutic interventions have dramatically improved the outlook for patients with this disorder and it is no longer a disease of childhood. Along with these changes chest physiotherapy has also progressed, with the development of several treatment modalities that are more effective and can be performed by the patient without assistance. This allows older children and adults with CF to lead more normal and independent lifestyles. Despite this progress questions remain regarding the efficacy and consequences of airway clearance techniques, the scientific evidence available to support the selection of the most appropriate treatment modality and, not least, the problems associated with the treatment-related burden that is placed on patients and their families.
authors.affiliation: Cystic Fibrosis Unit, Great Ormond Street Hospital for Children NHS Trust, London, UK.
authors.forename: S A
authors.initials: SA
authors.lastname: Prasad
authors.forename: E
authors.initials: E
authors.lastname: Main
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003550:Cystic Fibrosis / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D019317:Evidence-Based Medicine; D006801:Humans; D008019:Life Style; D009079:Mucociliary Clearance; D012107:Research Design; D012138:Respiratory Therapy / Q000379:methods* / Q000639:trends