title: Active site mutants of a cyclosporin A-insensitive cyclophilin from Brugia malayi: effect on catalysis and drug binding.
authors.affiliation: New England Biolabs, Beverly, MA 01915, USA.
authors.forename: D
authors.initials: D
authors.lastname: Ma
authors.forename: C K
authors.initials: CK
authors.lastname: Carlow
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites / Q000235:genetics; D017178:Brugia malayi / Q000201:enzymology / Q000235:genetics*; D002384:Catalysis / Q000187:drug effects; D016572:Cyclosporine / Q000494:pharmacology*; D017931:DNA Primers; D004351:Drug Resistance / Q000235:genetics; D008969:Molecular Sequence Data; D016296:Mutagenesis; D019696:Peptidylprolyl Isomerase / Q000737:chemistry / Q000187:drug effects / Q000235:genetics* / Q000378:metabolism; D017386:Sequence Homology, Amino Acid; D013329:Structure-Activity Relationship
chemical_list: D017931:DNA Primers; D016572:Cyclosporine; D019696:Peptidylprolyl Isomerase