title: [Sicca symptoms and hearing loss in Behçet's syndrome].
abstract: METHODS
  A 39-year-old woman sustained an irreversible hearing loss in the left ear, followed 6 months later by a left facial paresis. Oral aphthous ulcers frequently recurred with fever of up to 39.5 degrees C. Her general condition was noticeably poor.
  
  
  METHODS
  An inflammatory disease was suggested by an increased erythrocyte sedimentation rate (70/100 mm), leucocytosis (18,500/microliter), decreased haemoglobin (10.2 g/l) and leftward shift of the neutrophil granulocytes. Diagnostic tests for an infectious, autoimmune or haemato-oncological disease were negative.
  
  
  METHODS
  Antibiotic and antimycotic treatment failed to bring lasting improvement. Thrombophlebitis and venous thrombosis developed in both upper limbs and acute episcleritis (scleritis) in the left eye. Behçet's disease with oral, ocular, neurological, cutaneous and vascular involvement was diagnosed and treated with chlorambucil (variable dosage around 7 mg/d orally), with rapid regression of symptoms. 3 months later joint pains set in, and another 18 months later she developed sicca symptoms (xerostomia with dry eyes): both responded to symptomatic treatment.
  
  
  CONCLUSIONS
  The combination of loss of hearing, sicca syndrome and Behçet's syndrome has not been previously reported.
authors.affiliation: Rehabilitationsklinik Nordfriesland, St. Peter-Ording. Reha.NF@t-online.de
authors.forename: A
authors.initials: A
authors.lastname: Eichhorn
authors.forename: W
authors.initials: W
authors.lastname: Kirch
mesh_terms: D000328:Adult; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D001799:Blood Sedimentation; D005158:Facial Paralysis / Q000150:complications; D005260:Female; D034381:Hearing Loss / Q000150:complications*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D007958:Leukocyte Count; D009504:Neutrophils / Q000166:cytology; D015423:Scleritis / Q000150:complications; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D013281:Stomatitis, Aphthous / Q000150:complications; D013924:Thrombophlebitis / Q000150:complications
chemical_list: D006454:Hemoglobins
vernacular_title: Sicca-Symptomatik und Hörverlust beim Behçet-Syndrom.