Adaptation of a strain of Plasmodium vivax from Mauritania to New World monkeys and anopheline mosquitoes.
A strain of Plasmodium vivax from Mauritania was adapted to develop in Aotus lemurinus griseimembra, Aotus nancymai, Saimiri boliviensis, and hybrid Aotus monkeys. Infections were induced via the inoculation of sporozoites dissected from the salivary glands of Anopheles gambiae, Anopheles freeborni, and Anopheles stephensi mosquitoes or the intravenous passage of infected erythrocytes. Infections in 3 A. lemurinus griseimembra monkeys readily infected mosquitoes. Four lines of the Mauritania parasites have been stored frozen for further reference.
Collins
W E
WE
Division of Parasitic Diseases and Scientific Resources Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Department of Health and Human Services, Chamblee, Georgia 30341, USA.
Nguyen-Dinh
P
P
Sullivan
J S
JS
Morris
C L
CL
Galland
G G
GG
Richardson
B B
BB
Nesby
S
S
D000222:Adaptation, Physiological; D000818:Animals; D000852:Anopheles / Q000469:parasitology*; D000962:Antimalarials / Q000627:therapeutic use; D016645:Aotidae / Q000469:parasitology*; D002738:Chloroquine / Q000627:therapeutic use; D004195:Disease Models, Animal; D004359:Drug Therapy, Combination; D004912:Erythrocytes / Q000469:parasitology; D006801:Humans; D007303:Insect Vectors / Q000469:parasitology*; D016780:Malaria, Vivax / Q000188:drug therapy / Q000469:parasitology*; D008435:Mauritania; D010966:Plasmodium vivax / Q000502:physiology*; D011319:Primaquine / Q000627:therapeutic use; D012008:Recurrence; D012453:Saimiri / Q000469:parasitology*
D000962:Antimalarials; D002738:Chloroquine; D011319:Primaquine