title: Outcomes of ultrarapid opiate detoxification combined with naltrexone maintenance and counseling.
abstract: Combining naltrexone and clonidine under general anesthesia is being used to shorten opiate detoxification. This study determined the one-year relapse rate of persons detoxified using this ultrarapid method in conjunction with naltrexone maintenance and counseling. Structured telephone interviews were held with 83 out of a random sample of 113 male patients who were detoxified via the ultrarapid method more than one year before the interview (average 1.5 years) and their significant others. Relapse was defined as at least two weeks of daily opiate use. According to patients and significant others, 57 percent of patients had not relapsed. This rate is better than rates obtained in studies of other detoxification methods.
authors.affiliation: School of Social Work, Bar Ilan University, Ramat Gan, Israel. rabinowz@ashur.cc.biu.ac.il
authors.forename: J
authors.initials: J
authors.lastname: Rabinowitz
authors.forename: H
authors.initials: H
authors.lastname: Cohen
authors.forename: M
authors.initials: M
authors.lastname: Kotler
mesh_terms: D000328:Adult; D000768:Anesthesia, General; D003000:Clonidine / Q000008:administration & dosage* / Q000009:adverse effects; D003131:Combined Modality Therapy; D003376:Counseling; D005500:Follow-Up Studies; D006801:Humans; D007362:Intensive Care Units; D007557:Israel; D008297:Male; D008875:Middle Aged; D009271:Naltrexone / Q000008:administration & dosage* / Q000009:adverse effects; D009292:Narcotic Antagonists / Q000008:administration & dosage* / Q000009:adverse effects; D009293:Opioid-Related Disorders / Q000534:rehabilitation*; D012008:Recurrence; D013565:Sympatholytics / Q000008:administration & dosage* / Q000009:adverse effects; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D009292:Narcotic Antagonists; D013565:Sympatholytics; D009271:Naltrexone; D003000:Clonidine