title: Optic neuropathy in a child with primary Sjögren's syndrome.
abstract: An eight-year-old girl developed optic neuritis followed by primary Sjögren's syndrome confirmed by a lip biopsy. Glucocorticoid therapy combined during six months with monthly intravenous pulse cyclophosphamide ensured resolution of the sicca syndrome but failed to improve the visual impairment. This is the second pediatric case of optic neuritis associated with primary Sjögren's syndrome, and the first pediatric case in which optic neuritis was the only neurologic manifestation.
authors.affiliation: Department of Rheumatology, Specialties Hospital, Manuel Avila Camacho National Medical Center, Puebla, Mexico.
authors.forename: J
authors.initials: J
authors.lastname: Rojas-Rodriguez
authors.forename: M
authors.initials: M
authors.lastname: Garcia-Carrasco
authors.forename: E S
authors.initials: ES
authors.lastname: Ramirez
authors.forename: F
authors.initials: F
authors.lastname: Romero-Rodriguez
authors.forename: M
authors.initials: M
authors.lastname: Ramos-Casals
authors.forename: J
authors.initials: J
authors.lastname: Rojas-Serrano
authors.forename: A
authors.initials: A
authors.lastname: Terrazas-Ramirez
mesh_terms: D000293:Adolescent; D001707:Biopsy, Needle; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D019586:Intracranial Hypertension / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D009902:Optic Neuritis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D011239:Prednisolone / Q000627:therapeutic use; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis
chemical_list: D005938:Glucocorticoids; D011239:Prednisolone