title: Internal jugular vein thrombosis in association with the factor V Leiden mutation.
abstract: We report an unusual case of internal jugular vein thrombosis in a 57-year-old female, with the recently discovered factor V Leiden (FVR506Q) mutation. The molecular basis of this mutation is described, and the importance of screening for hereditary venous thrombotic states is emphasized.
authors.affiliation: Department of Otolaryngology, Addenbrookes Hospital, Cambridge.
authors.forename: P
authors.initials: P
authors.lastname: Arullendran
authors.forename: P
authors.initials: P
authors.lastname: Jani
authors.forename: T
authors.initials: T
authors.lastname: Baglin
authors.forename: D A
authors.initials: DA
authors.lastname: Moffat
mesh_terms: D005165:Factor V / Q000235:genetics*; D005260:Female; D006801:Humans; D007601:Jugular Veins / Q000000981:diagnostic imaging* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D017354:Point Mutation; D011859:Radiography; D013927:Thrombosis / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000235:genetics*
chemical_list: D005165:Factor V