Long-term treatment with CsA decreases INF-gamma mRNA and increases pre-pro-ET-1 mRNA in rat kidneys.
Murer
L
L
Department of Pediatrics, University of Padova, Italy.
Giacomini
A
A
Gambaro
G
G
Del Prete
D
D
Dall'Amico
R
R
Pagetta
E
E
Zacchello
G
G
Anglani
F
F
D000818:Animals; D016572:Cyclosporine / Q000494:pharmacology*; D004334:Drug Administration Schedule; D019332:Endothelin-1; D016232:Endothelins / Q000096:biosynthesis*; D007150:Immunohistochemistry; D007371:Interferon-gamma / Q000096:biosynthesis*; D007668:Kidney / Q000187:drug effects / Q000276:immunology* / Q000502:physiology; D008297:Male; D011498:Protein Precursors / Q000096:biosynthesis*; D012333:RNA, Messenger / Q000096:biosynthesis; D051381:Rats; D017208:Rats, Wistar; D014158:Transcription, Genetic / Q000187:drug effects / Q000276:immunology*; D016212:Transforming Growth Factor beta / Q000096:biosynthesis
D019332:Endothelin-1; D016232:Endothelins; D011498:Protein Precursors; D012333:RNA, Messenger; D016212:Transforming Growth Factor beta; D007371:Interferon-gamma; D016572:Cyclosporine