Surgical approach of an early mammalian embryo: the rabbit model.
We describe an experimental surgical model in early rabbit embryo (12.5 days of gestation). Twenty-one embryos were operated, of which 9 survived the first postoperative week and 5 had normal further growth until term. As far as we can ascertain, this is the first successful report of a surgical approach in early mammalian embryos. We think that this model may be useful for workers involved in the study of early congenital malformations.
Beaudoin
S
S
Department of Pediatric Surgery, Hôpital Saint-Vincent de Paul, Paris, France.
Simon
L
L
Simeoni
J
J
Sacquin
P
P
Bargy
F
F
D000818:Animals; D000013:Congenital Abnormalities; D004622:Embryo, Mammalian / Q000601:surgery*; D005314:Embryonic and Fetal Development; D005240:Feasibility Studies; D005260:Female; D005865:Gestational Age; D008954:Models, Biological; D011247:Pregnancy; D011817:Rabbits