title: Irinotecan and 5-fluorouracil in colorectal cancer: time for a pause?
authors.affiliation: Oncology Centre, Addenbrooke's Hospital, Cambridge, U.K.
authors.forename: V R
authors.initials: VR
authors.lastname: Bulusu
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D002453:Cell Cycle / Q000187:drug effects; D017322:Clinical Trials, Phase II as Topic; D015179:Colorectal Neoplasms / Q000188:drug therapy*; D004273:DNA, Neoplasm / Q000096:biosynthesis; D004357:Drug Synergism; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D000077146:Irinotecan; D016896:Treatment Outcome
chemical_list: D004273:DNA, Neoplasm; D000077146:Irinotecan; D005472:Fluorouracil; D002166:Camptothecin