title: Visual improvement during octreotide therapy in a case of episellar meningioma.
abstract: Meningiomas of the tuberculum sellae can induce compression of the optic tract. We report the case of a 54-year-old female patient affected by a suspected pituitary macroadenoma with severe visual field defects, who experienced a significant clinical and visual improvement during short-term octreotide therapy, contrasting with the lack of neuroradiological evidence for tumor shrinkage. The patient subsequently underwent transcranial surgery with a final diagnosis of meningioma. The putative mechanisms of visual improvement during octreotide therapy are discussed.
authors.affiliation: Dipartimento di Medicina Sperimentale, Università degli Studi, L'Aquila (AQ), Italy.
authors.forename: M L
authors.initials: ML
authors.lastname: Jaffrain-Rea
authors.forename: G
authors.initials: G
authors.lastname: Minniti
authors.forename: A
authors.initials: A
authors.lastname: Santoro
authors.forename: S
authors.initials: S
authors.lastname: Bastianello
authors.forename: G
authors.initials: G
authors.lastname: Tamburrano
authors.forename: A
authors.initials: A
authors.lastname: Gulino
authors.forename: G
authors.initials: G
authors.lastname: Cantore
mesh_terms: D000236:Adenoma / Q000175:diagnosis*; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D008579:Meningioma / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D008875:Middle Aged; D015282:Octreotide / Q000627:therapeutic use*; D010911:Pituitary Neoplasms / Q000175:diagnosis*; D016896:Treatment Outcome; D014786:Vision Disorders / Q000188:drug therapy* / Q000209:etiology
chemical_list: D018931:Antineoplastic Agents, Hormonal; D015282:Octreotide