title: Protein patterning.
abstract: The current technology available for patterning proteins is reviewed. Examples of two-dimensional protein patterning using conventional photolithographic methods, photochemistry, and self-assembled monolayers are given. Consideration is also given to some major issues affecting protein patterning, including non-specific binding, protein pattern uniformity, and measurement techniques. S-layer nanopatterning and three-dimensional biochip patterning are discussed in possible future directions. In addition, a discussion of the impact of protein patterning technology on the field of biomaterials is discussed.
authors.affiliation: NSF/ERC Center For Emerging Cardiovascular Technologies, Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
authors.forename: A S
authors.initials: AS
authors.lastname: Blawas
authors.forename: W M
authors.initials: WM
authors.lastname: Reichert
mesh_terms: D001709:Biotechnology / Q000379:methods*; D011506:Proteins / Q000737:chemistry*
chemical_list: D011506:Proteins