title: Detection of human chorionic gonadotrophin misuse in sports.
abstract: The peptide hormone human chorionic gonadotrophin (hCG) was measured in the urine of 5663 male athletes collected for doping analysis in Flanders during the period 1993-1996. Using the Abbott IMx hCG procedure, the free and whole molecule associated beta-subunit of human chorionic gonadotrophin was determined. Statistical evaluation of the data results in a far outside value of 2.28 mIU/ml. The decision limit, i.e. the concentration at which a sportsman will be considered positive, is set at 5 mIU/ml to ensure with the greatest possible degree of certainty that no false positive results are reported.
authors.affiliation: Dept. Pharmacology and Toxicology, Faculty of Veterinary Medicine, University Gent, Belgium.
authors.forename: F T
authors.initials: FT
authors.lastname: Delbeke
authors.forename: P
authors.initials: P
authors.lastname: Van Eenoo
authors.forename: P
authors.initials: P
authors.lastname: De Backer
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D018997:Chorionic Gonadotropin, beta Subunit, Human / Q000652:urine*; D004300:Doping in Sports; D006801:Humans; D007124:Immunoenzyme Techniques / Q000295:instrumentation* / Q000592:standards; D008297:Male; D008875:Middle Aged; D012016:Reference Values
chemical_list: D018997:Chorionic Gonadotropin, beta Subunit, Human