[Muscular enzyme level disorders and a malignant hyperthermia susceptability test: postoperative study of a patient with elevated CPK].
The preoperative evaluation of the enzymatic level concerning the functioning of the neuromuscular system, is of particular importance. The diseases of these regions may lead to Malignant Hyperthermia (MH) in the course of general anaesthesia. The authors illustrate the case of a young asymptomatic patient with constantly high levels of CPK, who was later affected by Central Core Disease (CCD), a rare hereditary slow progressing myopathy strictly related to MH. The authors suggest tat preoperative CPK levels, though not predictive of a patient to develop MH, can allow identification of patients affected by clinically silent myopathies. This can also acquire legal importance in case of clinical MH manifestation.
Perugini
M
M
Servizio di Anestesia e Rianimazione, ASL 9, Macerata.
Montironi
C
C
Rocchi
S
S
D000328:Adult; D003402:Creatine Kinase / Q000378:metabolism*; D004798:Enzymes / Q000378:metabolism*; D005260:Female; D006801:Humans; D008305:Malignant Hyperthermia / Q000175:diagnosis*; D009135:Muscular Diseases / Q000150:complications / Q000201:enzymology*; D011184:Postoperative Period
D004798:Enzymes; D003402:Creatine Kinase
Valori costantemente alterati degli enzimi muscolari e test di suscettibilità all'ipertermia maligna: studio preoperatorio di un paziente con CPK elevato.