The effectiveness of intermittent hyperbaric oxygen in relieving drug-induced HIV-associated neuropathy.
This 3-month study evaluated the effects of hyperbaric oxygen on drug-induced neuropathies in 22 patients with human immunodeficiency virus. All patients included in the study had been taking an antiretroviral medication for at least 12 months and had subjective symptoms of numbness or tingling, lethargy, and a decrease in deep tendon reflex. Patients with an active substance abuse history or Kaposi's sarcoma were excluded. Of the 20 patients who completed the series, 17 had significant improvement, 2 had a demyelinating disorder that may have affected the outcome, and 1 had no change.
Jordan
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Department of Internal Medicine, Charles R. Drew University of Medicine and Science, King-Drew Medical Center, Los Angeles, California 90059, USA.
D019380:Anti-HIV Agents / Q000009:adverse effects* / Q000627:therapeutic use; D002908:Chronic Disease; D004359:Drug Therapy, Combination; D005221:Fatigue / Q000209:etiology / Q000628:therapy*; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D010523:Peripheral Nervous System Diseases / Q000139:chemically induced* / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome
D019380:Anti-HIV Agents