Remodelling and restenosis: intravascular ultrasound studies.
Remodelling, defined as a change in total vessel area, was demonstrated to be another important mechanism of restenosis after coronary angioplasty in a study utilizing intravascular ultrasound. In this study, remodelling was also demonstrated to be bidirectional (constrictive modelling and adaptive remodelling). A recent serial intravascular ultrasound study revealed that time course of remodelling after coronary angioplasty was typically biphasic; early (post-procedure-1 month) adaptive remodelling and late (1 month-6 months) constrictive remodelling. Remodelling after coronary angioplasty should be regarded not only as a cause of restenosis but also as a mechanism maintaining patency.
Kimura
T
T
Department of Cardiology, Kokura Memorial Hospital, Kitakyushu, Japan.
Nobuyoshi
M
M
D015906:Angioplasty, Balloon, Coronary; D017225:Atherectomy, Coronary; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000503:physiopathology / Q000628:therapy; D003331:Coronary Vessels / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D012008:Recurrence; D018084:Ultrasonography, Interventional