title: Changes on the Temperament and Character Inventory after paroxetine treatment in volunteers with generalized anxiety disorder.
abstract: Previously untreated symptomatic volunteers with generalized anxiety disorder (GAD) performed the Temperament and Character Inventory at baseline and after 4 to 6 months of paroxetine treatment. Scores from 29 volunteers were analyzed with paired t-tests. A marked reduction was noted in Harm Avoidance and a marked increase was noted in Self-Directedness. Smaller changes were noted in Cooperativeness and Novelty Seeking. Overall, treatment was associated with a reduction in maladaptive personality traits.
authors.affiliation: Karolinska Institutet, Huddinge Hospital, Sweden.
authors.forename: C
authors.initials: C
authors.lastname: Allgulander
authors.forename: C R
authors.initials: CR
authors.lastname: Cloninger
authors.forename: T R
authors.initials: TR
authors.lastname: Przybeck
authors.forename: L
authors.initials: L
authors.lastname: Brandt
mesh_terms: D000328:Adult; D000379:Agoraphobia / Q000188:drug therapy* / Q000523:psychology*; D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use*; D002605:Character; D006801:Humans; D017374:Paroxetine / Q000627:therapeutic use*; D011569:Psychiatric Status Rating Scales; D013694:Temperament / Q000187:drug effects*
chemical_list: D018687:Antidepressive Agents, Second-Generation; D017374:Paroxetine