title: Multiple myeloma-associated amyloidosis and giant cell arteritis.
abstract: Primary systemic amyloidosis has been associated with the development of symptoms and clinical features characteristic of polymyalgia rheumatica and/or giant cell arteritis (GCA). Case reports of this clinical entity have been published, stating that the amyloid deposition leads to the symptoms of vasculitis. In this report, we present a second case in the English literature of a patient presenting with multiple myeloma-associated amyloidosis and GCA. This is the first case in which the histopathologic findings are described in enough detail to suggest a pathogenic relationship between the two diseases.
authors.affiliation: Duke University Medical Center, Durham, North Carolina 27710, USA.
authors.forename: A
authors.initials: A
authors.lastname: Estrada
authors.forename: T T
authors.initials: TT
authors.lastname: Stenzel
authors.forename: J L
authors.initials: JL
authors.lastname: Burchette
authors.forename: N B
authors.initials: NB
authors.lastname: Allen
mesh_terms: D000368:Aged; D000686:Amyloidosis / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D001402:B-Lymphocytes / Q000166:cytology; D017809:Fatal Outcome; D005260:Female; D013700:Giant Cell Arteritis / Q000175:diagnosis* / Q000276:immunology / Q000473:pathology; D006801:Humans; D007124:Immunoenzyme Techniques; D008264:Macrophages / Q000166:cytology; D009101:Multiple Myeloma / Q000175:diagnosis*; D013601:T-Lymphocytes / Q000166:cytology