Development of a macromolecular prodrug of FK 506: II: In vitro study for FK 506-dextran conjugate.
Yura
H
H
Department of Drug Delivery Research, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan.
Yoshimura
N
N
Hamashima
T
T
Oka
T
T
Takakura
Y
Y
Hashida
M
M
D000818:Animals; D002478:Cells, Cultured; D003911:Dextrans / Q000494:pharmacology*; D007166:Immunosuppressive Agents / Q000494:pharmacology; D008213:Lymphocyte Activation / Q000187:drug effects*; D008214:Lymphocytes / Q000187:drug effects / Q000276:immunology*; D011355:Prodrugs / Q000494:pharmacology*; D051381:Rats; D016559:Tacrolimus / Q000494:pharmacology*
D003911:Dextrans; C112843:FK 506-dextran conjugate; D007166:Immunosuppressive Agents; D011355:Prodrugs; D016559:Tacrolimus