title: Endoscopic resection of small duodenal carcinoid tumors with strip biopsy technique.
abstract: BACKGROUND
  Most cases of duodenal carcinoid have conventionally been treated by surgical resection. The aim of our study was to explore the feasibility of endoscopic resection in small duodenal carcinoids.
  
  
  METHODS
  The study population consisted of seven patients with small duodenal carcinoids. The diagnosis was confirmed by preoperative biopsies. The depth of tumor invasion was evaluated by endosonography.
  
  
  RESULTS
  The carcinoid was detected by endosonography in all cases. Size ranged ultrasonographically from 1.5 mm to 7 mm. Tumor invasion was confined to the submucosa in all patients. Endoscopic resection was performed with the strip biopsy technique using a two-channel endoscope. In six patients, the specimens were resected without severe complications. Five of them were confirmed histologically to be typical carcinoids. In one patient, carcinoid was not detected histologically in the specimen. In the remaining patient, a perforation occurred. However, the huge ulcer was managed conservatively. Follow-up endoscopy revealed no evidence of recurrent or residual tumor in any patient.
  
  
  CONCLUSIONS
  Small duodenal carcinoids confined to the submucosa can be resected endoscopically and preoperative endosonography is necessary for the determination of endoscopic resectability.
authors.affiliation: Department of Internal Medicine, Handa City Hospital, Handa, Aichi, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Yoshikane
authors.forename: H
authors.initials: H
authors.lastname: Goto
authors.forename: Y
authors.initials: Y
authors.lastname: Niwa
authors.forename: M
authors.initials: M
authors.lastname: Matsui
authors.forename: S
authors.initials: S
authors.lastname: Ohashi
authors.forename: T
authors.initials: T
authors.lastname: Suzuki
authors.forename: E
authors.initials: E
authors.lastname: Hamajima
authors.forename: T
authors.initials: T
authors.lastname: Hayakawa
mesh_terms: D000368:Aged; D001707:Biopsy, Needle / Q000379:methods*; D002276:Carcinoid Tumor / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D004379:Duodenal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D004384:Duodenoscopy; D004724:Endoscopy / Q000379:methods*; D019160:Endosonography; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome