title: Constant hierarchic patterns of physical functioning across seven populations in five countries.
abstract: This research was aimed at identifying critical steps in the decline in physical function that often parallels aging. Six basic and nine instrumental activities of daily living (ADLs) were classified into four domains of disability characterized by specific underlying physical impairment. The hierarchical order of this classification was verified in two random samples representative of the older home-dwelling population. The concordance level of disability and results of performance-based measures of physical function were also tested. Finally, the cross-cultural reliability of the model was verified in seven population-based samples of older persons living in five European countries. In older persons the disabling process follows a general pattern of progression based on a typical sequence of impairments.
authors.affiliation: INRCA Geriatric Department I Fraticini, Firenze, Italy. ferrucci@dada.it
authors.forename: L
authors.initials: L
authors.lastname: Ferrucci
authors.forename: J M
authors.initials: JM
authors.lastname: Guralnik
authors.forename: F
authors.initials: F
authors.lastname: Cecchi
authors.forename: N
authors.initials: N
authors.lastname: Marchionni
authors.forename: B
authors.initials: B
authors.lastname: Salani
authors.forename: J
authors.initials: J
authors.lastname: Kasper
authors.forename: R
authors.initials: R
authors.lastname: Celli
authors.forename: S
authors.initials: S
authors.lastname: Giardini
authors.forename: E
authors.initials: E
authors.lastname: Heikkinen
authors.forename: M
authors.initials: M
authors.lastname: Jylhä
authors.forename: A
authors.initials: A
authors.lastname: Baroni
mesh_terms: D000203:Activities of Daily Living; D000368:Aged / Q000706:statistics & numerical data*; D000369:Aged, 80 and over; D000704:Analysis of Variance; D003431:Cross-Cultural Comparison; D005060:Europe / Q000453:epidemiology; D005163:Factor Analysis, Statistical; D016330:Frail Elderly / Q000706:statistics & numerical data*; D006304:Health Status; D006801:Humans; D008875:Middle Aged; D015203:Reproducibility of Results