Clarithromycin induced digoxin toxicity.
A case of digoxin poisoning following the co-administration of digoxin and clarithromycin in a 28 year old male is described. Since the aetiology of chronic digoxin poisoning is often unclear, clinicians should be aware of the potential drug-drug interaction between digoxin and clarithromycin.
Nordt
S P
SP
California Poison Control System-San Diego Division and Division of Medical Toxicology University of California, San Diego Medical Center, 92103-8925, USA. snordt@ucsd.edu
Williams
S R
SR
Manoguerra
A S
AS
Clark
R F
RF
D000328:Adult; D000855:Anorexia / Q000139:chemically induced; D000889:Anti-Arrhythmia Agents / Q000506:poisoning* / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D017291:Clarithromycin / Q000009:adverse effects* / Q000627:therapeutic use; D004077:Digoxin / Q000506:poisoning* / Q000627:therapeutic use; D004347:Drug Interactions; D004359:Drug Therapy, Combination; D004636:Emergency Service, Hospital; D006801:Humans; D008297:Male; D014839:Vomiting / Q000139:chemically induced
D000889:Anti-Arrhythmia Agents; D000900:Anti-Bacterial Agents; D004077:Digoxin; D017291:Clarithromycin