title: Depressive symptoms and Depo-Provera.
abstract: Women enrolled in a multicenter prospective study were evaluated to identify any possible relationship between depressive symptoms and the use of contraceptives. Women choosing Depo-Provera (n = 495) were evaluated before starting these contraceptives and were reinterviewed 1 year later. Women who continued the method had lower depressive symptom scores at baseline than did the women who discontinued the method or who were lost to follow-up. Among the continuing Depo-Provera users, the depressive symptom scores improved slightly at 1 year (7.4 vs 6.7). Those subjects with the highest (i.e., worst) scores at enrollment demonstrated improved scores at follow-up.
authors.affiliation: College of Physicians and Surgeons, Columbia University, New York, New York, USA.
authors.forename: C
authors.initials: C
authors.lastname: Westhoff
authors.forename: C
authors.initials: C
authors.lastname: Truman
authors.forename: D
authors.initials: D
authors.lastname: Kalmuss
authors.forename: L
authors.initials: L
authors.lastname: Cushman
authors.forename: A
authors.initials: A
authors.lastname: Davidson
authors.forename: M
authors.initials: M
authors.lastname: Rulin
authors.forename: S
authors.initials: S
authors.lastname: Heartwell
mesh_terms: D000293:Adolescent; D000328:Adult; D003271:Contraceptive Agents, Female / Q000009:adverse effects*; D003863:Depression / Q000139:chemically induced*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D017258:Medroxyprogesterone Acetate / Q000009:adverse effects*; D019964:Mood Disorders / Q000139:chemically induced; D011446:Prospective Studies; D011795:Surveys and Questionnaires
chemical_list: D003271:Contraceptive Agents, Female; D017258:Medroxyprogesterone Acetate