title: External quality assessment of molecular biology-based methods used in laboratories of clinical chemistry and human genetics.
abstract: The Reference Institute of Bioanalysis of the German Society of Clinical Chemistry has performed the first external assessment of molecular genetics methods used in medical diagnosis. The following procedures were tested: (I) DNA preparation from whole blood, (II) PCR amplification using "standard" primers, and (III) submarine agarose gel electrophoresis. Out of 50 participants, 45 returned samples for evaluation.
authors.affiliation: Abteilung für Klinische Chemie und Biochemie, Dr. von Haunersches Kinderspital, Ludwigs-Maximilians-Universität, München, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Braun
authors.forename: T
authors.initials: T
authors.lastname: Deufel
authors.forename: W J
authors.initials: WJ
authors.lastname: Geilenkeuser
authors.forename: M
authors.initials: M
authors.lastname: Neumaier
authors.forename: G
authors.initials: G
authors.lastname: Röhle
authors.forename: A
authors.initials: A
authors.lastname: Roscher
authors.forename: C
authors.initials: C
authors.lastname: Wagener
mesh_terms: D002624:Chemistry, Clinical / Q000592:standards*; D004247:DNA / Q000235:genetics / Q000302:isolation & purification; D005826:Genetics, Medical / Q000592:standards*; D005858:Germany; D006801:Humans; D007753:Laboratories / Q000592:standards*; D008967:Molecular Biology / Q000592:standards; D016133:Polymerase Chain Reaction / Q000592:standards; D011786:Quality Control
chemical_list: D004247:DNA