title: The yvsA-yvqA (293 degrees-289 degrees) region of the Bacillus subtilis chromosome containing genes involved in metal ion uptake and a putative sigma factor.
abstract: The region between yvsA (293 degrees) and yvqA (289 degrees) of the Bacillus subtilis chromosome has been sequenced within the framework of the B. subtilis 168 international sequencing programme. A primary analysis of the 42 ORFs identified in this 43 kb region is presented. The region included a high proportion of genes that did not show homology with genes in other bacteria. The identified ORFs showed homology to proteins involved in the transport of metal ions, two-component signal transducers, ATP-binding-cassette-type transporters and a sigma factor.
authors.affiliation: School of Microbiological, Immunological and Virological Sciences, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
authors.forename: Anil
authors.initials: A
authors.lastname: Wipat
authors.affiliation: School of Microbiological, Immunological and Virological Sciences, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
authors.forename: S Caroline
authors.initials: SC
authors.lastname: Brignell
authors.affiliation: School of Microbiological, Immunological and Virological Sciences, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
authors.forename: B Jane
authors.initials: BJ
authors.lastname: Guy
authors.affiliation: Johann Wolfgang Goethe-Universitaet Frankfurt, Institut für Mikrobiologie, Marie-Curie-Str., 9 Geb. N250, 60439 Frankfurt am Main, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Rose
authors.affiliation: Department of Biochemistry & Genetics, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
authors.forename: Peter T
authors.initials: PT
authors.lastname: Emmerson
authors.affiliation: School of Microbiological, Immunological and Virological Sciences, University of Newcastle upon Tyne, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
authors.forename: Colin R
authors.initials: CR
authors.lastname: Harwood
mesh_terms: D018528:ATP-Binding Cassette Transporters / Q000235:genetics; D001412:Bacillus subtilis / Q000235:genetics*; D001483:Base Sequence; D002874:Chromosome Mapping; D002876:Chromosomes, Bacterial / Q000235:genetics* / Q000378:metabolism; D008670:Metals / Q000378:metabolism*; D008969:Molecular Sequence Data; D016366:Open Reading Frames / Q000235:genetics*; D016133:Polymerase Chain Reaction; D017385:Sequence Homology; D012808:Sigma Factor / Q000235:genetics*; D015398:Signal Transduction
chemical_list: D018528:ATP-Binding Cassette Transporters; D008670:Metals; D012808:Sigma Factor