Membrane fusion: all done with SNAREpins?
SNARE proteins are sufficient to fuse artificial membranes together. In the cell, vesicle transport may rely on fusion mediated by interaction between vesicle (v) and target (t) SNAREs, whereas the homotypic fusion of organelle biogenesis may be mediated by t-SNARE-t-SNARE interaction.
Edwardson
J M
JM
Department of Pharmacology, University of Cambridge, UK. jme1000@cus.cam.ac.uk
D002352:Carrier Proteins / Q000502:physiology; D046911:Macromolecular Substances; D008561:Membrane Fusion / Q000502:physiology*; D008565:Membrane Proteins / Q000737:chemistry / Q000502:physiology*; D008954:Models, Biological; D052066:N-Ethylmaleimide-Sensitive Proteins; D050600:SNARE Proteins; D012441:Saccharomyces cerevisiae / Q000502:physiology; D033921:Vesicular Transport Proteins
D002352:Carrier Proteins; D046911:Macromolecular Substances; D008565:Membrane Proteins; D050600:SNARE Proteins; D033921:Vesicular Transport Proteins; D052066:N-Ethylmaleimide-Sensitive Proteins