Muir-Torre syndrome.
Muir-Torre syndrome is a rare autosomal dominant disorder characterized by unusual sebaceous neoplasms and visceral malignancy. Excluding sebaceous hyperplasia and sebaceous nevus of Jadassohn, sebaceous neoplasms occur so rarely that the presence of a sebaceous neoplasm mandates consideration of Muir-Torre syndrome. Sebaceous neoplasms precede or are synchronous with visceral malignancies in up to 40% or more of patients with Muir-Torre syndrome, and the presence of such a lesion warrants an evaluation for visceral malignancy.
Johnson
P J
PJ
Section of Plastic and Reconstructive Surgery, University of Nebraska Medical Center, Omaha 68198-3335, USA.
Heckler
F
F
D000230:Adenocarcinoma / Q000601:surgery*; D018266:Adenocarcinoma, Sebaceous / Q000473:pathology / Q000601:surgery*; D000328:Adult; D001415:Back; D005260:Female; D006801:Humans; D016609:Neoplasms, Second Primary / Q000601:surgery*; D012004:Rectal Neoplasms / Q000601:surgery*; D012626:Sebaceous Gland Neoplasms / Q000473:pathology / Q000601:surgery*; D013577:Syndrome