Pyrrolizidine alkaloid-induced depletion of taurine from rat liver in vivo and in vitro.
Sun
Y
Y
Department of Pharmacology, University of Arizona, College of Medicine, Tucson 85724, USA.
Hasal
S J
SJ
Yan
C C
CC
Brendel
K
K
Huxtable
R J
RJ
D000818:Animals; D066298:In Vitro Techniques; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D016686:Monocrotaline / Q000008:administration & dosage / Q000494:pharmacology*; D010477:Perfusion; D011763:Pyrrolizidine Alkaloids / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D017207:Rats, Sprague-Dawley; D013654:Taurine / Q000378:metabolism*; D014118:Toxins, Biological / Q000008:administration & dosage / Q000494:pharmacology*
D011763:Pyrrolizidine Alkaloids; D014118:Toxins, Biological; D013654:Taurine; D016686:Monocrotaline; C003300:retrorsine