Early life markers of atopy and asthma.
Since early intervention could modulate the natural course of atopic disease, the availability of predictive markers is of considerable interest. As long as specific genetic markers are not available, early IgE-responses (hen's egg) together with a positive family history of atopy can be proposed as highly specific and predictive markers, which could define subgroups as potential candidates for secondary prevention.
Wahn
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Department of Paediatric Pneumology and Immunology, Humboldt-Universitaet zu Berlin, Germany.
Bergmann
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RL
Nickel
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D001249:Asthma / Q000276:immunology*; D015415:Biomarkers / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology*; D007073:Immunoglobulin E / Q000097:blood; D007223:Infant; D007231:Infant, Newborn
D015415:Biomarkers; D007073:Immunoglobulin E