Suggested ultrasound parameters for the assessment of fetal well-being during chronic hemodialysis.
There are no published guidelines on how to assess fetal well-being during hemodialysis. We have developed a specific protocol of renal and obstetric interventions to ensure that hemodialysis is associated with minimal changes in fetal status. We tested this protocol serially over a 9-week period in a pregnant patient who was undergoing chronic hemodialysis for end-stage renal disease. Testing involved serial assessments of uterine and umbilical artery blood flow with Doppler velocimetry and continuous fetal heart rate tracings, before, during and after each hemodialysis session. We found that, by strict adherence to these guidelines, there were no significant alterations in maternal mean arterial blood pressure, continuous fetal heart rate tracings, uterine artery systolic/diastolic ratios, or umbilical artery systolic/diastolic ratios. We conclude that stable uteroplacental and fetal perfusion can be maintained during chronic hemodialysis in pregnancy by adhering to a specific set of precautions.
Division of Maternal-Fetal Medicine, Tufts University School of Medicine, New England Medical Center, Boston, Massachusetts 02111, USA.
F D
FD
Malone
S D
SD
Craigo
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I
Giatras
J
J
Carlson
A
A
Athanassiou
M E
ME
D'Alton
D000328:Adult; D001795:Blood Pressure Determination; D005314:Embryonic and Fetal Development / Q000502:physiology*; D005260:Female; D005323:Fetal Monitoring / Q000379:methods*; D005328:Fetal Viability; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy; D011256:Pregnancy Outcome; D018566:Pregnancy, High-Risk; D011295:Prenatal Care; D006435:Renal Dialysis / Q000009:adverse effects; D016216:Ultrasonography, Prenatal / Q000379:methods*; D014469:Umbilical Arteries / Q000000981:diagnostic imaging