Effect of the extract of Annona muricata and Petunia nyctaginiflora on Herpes simplex virus.
Annona muricata (Annonaceae) and Petunia nyctaginiflora (Solanaceae) were screened for their activity against Herpes simplex virus-1 (HSV-1) and clinical isolate (obtained from the human keratitis lesion). We have looked at the ability of extract(s) to inhibit the cytopathic effect of HSV-1 on vero cells as indicative of anti-HSV-1 potential. The minimum inhibitory concentration of ethanolic extract of A. muricata and aqueous extract of P. nyctaginiflora was found to be 1 mg/ml.
Padma
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P
Department of Pharmaceutics, IT, Banaras Hindu University, Varanasi, India.
Pramod
N P
NP
Thyagarajan
S P
SP
Khosa
R L
RL
D000818:Animals; D002522:Chlorocebus aethiops; D018259:Herpesvirus 1, Human / Q000187:drug effects* / Q000302:isolation & purification / Q000472:pathogenicity; D006801:Humans; D007194:India; D008826:Microbial Sensitivity Tests; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal; D014709:Vero Cells / Q000187:drug effects / Q000821:virology
D010936:Plant Extracts