[Multiple and de novo aneurysms in Ehlers-Danlos syndrome].
OBJECTIVE
In 1964, the first case of "de novo" aneurysm has been reported by Graf and Hamby. The risk of late formation of aneurysm is unknown. Some factors could influence risk: history of hypertension, oral contraceptives, cigarette smoking. We report a rare case of "de novo" aneurysm associated with Ehlers-Danlos syndrome.


RESULTS
A 35-year-old female developed a subarachnoid hemorrhage (SAH). Angiography demonstrated 4 aneurysms. Five years before, she presented a SAH. At that time, four vessels angiography demonstrated only one PICA aneurysm. A Ehlers-Danlos syndrome was suspected, which was demonstrated on skin biopsies.


CONCLUSIONS
At our knowledge, this is the first case of "de novo" aneurysm associated with a Ehlers-Danlos syndrome.
De Witte
O
O
Service de Neurochirurgie, Hôpital Erasme, Bruxelles, Belgique.
Noterman
J
J
Oulad Ben Taib
N
N
Abramowicz
M
M
Balériaux
D
D
Vandesteene
A
A
Brotchi
J
J
D000328:Adult; D000783:Aneurysm / Q000209:etiology* / Q000503:physiopathology; D017542:Aneurysm, Ruptured / Q000209:etiology; D004535:Ehlers-Danlos Syndrome / Q000150:complications* / Q000503:physiopathology; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000209:etiology; D012008:Recurrence