The correlation between the numbers of some bacteria in human oral cavity and blood neutrophil count.
The correlation between the number of blood polymorphonuclear granulocytes (PMNs) and the counts of oral bacteria in 92 children (33 girls and 59 boys), aged 4-15 was investigated. The groups of children comprised 44 healthy individuals and 48 children suffering from acute lymphoblastic leukaemia who were given intensive antileukaemic chemotherapy. It was found that while the number of PMNs in blood decreased, the counts of Streptococcus spp., Staphylococcus spp., mutans streptococci, Lactobacillus spp., and Actinomyces spp. in the saliva tended to increase. The similar reciprocal correlation between the number of blood PMNs and the counts of these bacteria in the saliva was found in the group of healthy children. We concluded that the blood PMNs, by influencing the number of oral PMNs which control bacteria in this habitat, influence also the number of some groups of bacteria there.
Majda-Stanislawska
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Department of Infectious Diseases, Medical University of Lodz, Poland. ewiga@psk2.am.lodz.pl
Krzeminski
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D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001419:Bacteria / Q000254:growth & development* / Q000302:isolation & purification; D002648:Child; D002675:Child, Preschool; D015169:Colony Count, Microbial; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D008297:Male; D009504:Neutrophils; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000097:blood* / Q000188:drug therapy / Q000382:microbiology*; D012463:Saliva / Q000382:microbiology*