Antiacetylcholine receptor Fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant specificities in serum and block the action of pathogenic serum antibodies.
Graus
Y F
YF
Department of Immunology, Scripps Research Institute, La Jolla, California 92037, USA.
de Baets
M H
MH
Burton
D R
DR
D000918:Antibody Specificity; D001323:Autoantibodies / Q000097:blood*; D001435:Bacteriophages; D002478:Cells, Cultured; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000276:immunology* / Q000302:isolation & purification; D009157:Myasthenia Gravis / Q000276:immunology*; D019151:Peptide Library; D011950:Receptors, Cholinergic / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology
D001323:Autoantibodies; D007140:Immunoglobulin Fab Fragments; D019151:Peptide Library; D011950:Receptors, Cholinergic