[Epidemiology of systemic inflammatory response syndrome, infection and septic shock in surgical intensive care patients].
This paper uses definitions of a consensus conference (ACCP/CCM) describing the epidemiology of SIRS, sepsis and septic shock in surgical ICU patients. During a period of 2 years a total of 656 patients were prospectively enrolled into the study. 335 patients (51.1% of the total population) developed SIRS (systemic inflammatory response syndrome); in 65 of these patients infection could be documented, i.e. they met the criteria of sepsis, 47 of these 65 septic patients developed septic shock, with mortality of 53.2%. SIRS is associated with a high sensitivity but a low specificity in predicting the outcome of ICU patients. Moreover, SIRS and sepsis appear to be of minor clinical relevance. On the contrary, septic shock describes a very high risk group of patients which should be characterized more closely in future studies.
Wade
S
S
Klinik für Allgemeinchirurgie, Johann Wolfgang Goethe Universität, Frankfurt/Main.
Büssow
M
M
Hanisch
E
E
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D003430:Cross-Sectional Studies; D005260:Female; D005858:Germany / Q000453:epidemiology; D017052:Hospital Mortality; D006801:Humans; D015994:Incidence; D007362:Intensive Care Units / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000175:diagnosis / Q000401:mortality*; D011446:Prospective Studies; D012772:Shock, Septic / Q000175:diagnosis / Q000401:mortality*; D013530:Surgical Wound Infection / Q000175:diagnosis / Q000401:mortality*; D015996:Survival Rate; D018746:Systemic Inflammatory Response Syndrome / Q000175:diagnosis / Q000401:mortality*