Population genetic study of the simultaneously amplified loci HLA DQA1, LDLR, GYPA, HBGG, D7S8, and GC in a German population sample.
A population genetic study of the HLA DQA1 and the "Polymarker" loci LDLR, GYPA, HBG, D7S8, and GC has been performed in a German Caucasian population (Frankfurt am Main area). All loci are in Hardy-Weinberg equilibrium and no unexpected association of loci has been observed. The data of the allele distributions are similar to those of other Caucasian populations. All six loci together have a power of discrimination (PD) of 0.9996 and an exclusion chance in paternity testing of 0.81.
Zentrum der Rechtmedizin, J. W. Goethe-Universitat, Frankfurt, Germany.
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D000483:Alleles; D004247:DNA / Q000032:analysis*; D016172:DNA Fingerprinting / Q000379:methods; D005784:Gene Amplification; D008040:Genetic Linkage; D005828:Genetics, Population; D005858:Germany; D005936:Glucans / Q000235:genetics; D006683:HLA-DQ Antigens / Q000235:genetics; D059848:HLA-DQ alpha-Chains; D006801:Humans; D016133:Polymerase Chain Reaction; D011933:Reagent Kits, Diagnostic; D011973:Receptors, LDL / Q000235:genetics
D005936:Glucans; D006683:HLA-DQ Antigens; D059848:HLA-DQ alpha-Chains; C069050:HLA-DQA1 antigen; D011933:Reagent Kits, Diagnostic; D011973:Receptors, LDL; D004247:DNA; C042659:hexa(beta-glucopyranosyl)glucitol