The clinical use of androgens in female sexual disorders.
Sexual health is an important component of overall health and well being. Multiple factors clearly influence an individual's sexuality; however, there is a general trend in Western societies to blame psychosocial factors for diminished sexuality in women. Sex steroid hormones are important determinants of sexual function in women and men, and there is increasing agreement that androgens play a key role in female sexuality. Androgen levels in women decline substantially during the reproductive years, with little change subsequent to spontaneous menopause. The most common complaint of women experiencing androgen deficiency is loss of sexual desire, and several studies have now shown improvements in a number of parameters of sexuality in postmenopausal women treated with exogenous testosterone.
Jean Hailes Foundation, Clayton, Victoria, Australia.
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Davis
D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D007989:Libido / Q000187:drug effects / Q000502:physiology; D008875:Middle Aged; D017698:Postmenopause; D012725:Sexual Behavior / Q000187:drug effects / Q000523:psychology; D020018:Sexual Dysfunctions, Psychological / Q000188:drug therapy*; D013739:Testosterone / Q000378:metabolism / Q000627:therapeutic use*
D013739:Testosterone