Pneumonyssoides caninum infection--a risk factor for gastric dilatation-volvulus in dogs.
The pathophysiology, clinical course and therapeutic management of gastric dilatation-volvulus (GDV) in dogs are well known. However, the aetiology remains elusive. Aerophagia has often been put forward as a contributing cause of GDV. The most common clinical sign in dogs with nasal mite (Pneumonyssoides caninum) infection is 'reversed sneezing', which may result in aerophagia. A prospective one-year necropsy study was conducted. Of 250 dogs, 17 were GDV cases and, of these, 35% had concurrent nasal mite infection compared to 5% in the control population. Multivariate logistic regression analyses performed using the 187 dogs with complete records included nasal mite infection status, age, weight and gender. Nasal mite infection was found to be the most important risk factor for GDV in this study, with an odds ratio and confidence interval of 27.6 (4.8-157.5). Other risk factors that were marginally significant included weight and age with odds ratios of 1.08 (1.02-1.13) and 1.37 (1.04-1.79), respectively. Gender was not found to be a significant risk factor for GDV. This study suggests that nasal mite infection may contribute to the development of GDV in otherwise predisposed dogs.
Department of Small Animal Clinical Sciences, Norwegian College of Veterinary Medicine, Oslo, Norway.
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D000334:Aerophagy / Q000150:complications / Q000209:etiology / Q000662:veterinary; D017677:Age Distribution; D000818:Animals; D001835:Body Weight; D016001:Confidence Intervals; D004283:Dog Diseases / Q000453:epidemiology / Q000209:etiology*; D004285:Dogs; D005260:Female; D013271:Gastric Dilatation / Q000453:epidemiology / Q000209:etiology / Q000662:veterinary*; D016015:Logistic Models; D008297:Male; D008924:Mite Infestations / Q000150:complications / Q000662:veterinary*; D008925:Mites; D015999:Multivariate Analysis; D009296:Nasal Cavity / Q000469:parasitology*; D009664:Norway / Q000453:epidemiology; D009668:Nose Diseases / Q000150:complications / Q000662:veterinary*; D016017:Odds Ratio; D011446:Prospective Studies; D012307:Risk Factors; D017678:Sex Distribution; D013277:Stomach Volvulus / Q000453:epidemiology / Q000209:etiology / Q000662:veterinary*