Clonazepam as a therapeutic adjunct to improve the management of psychiatric disorders.
Clonazepam, which is a benzodiazepine structurally related to chlordiazepoxide hydrochloride, diazepam and nitrazepam, has been available for the treatment of seizure disorders in the USA since 1976 and in Japan since 1981. Increasingly, clonazepam has been used in the treatment of a variety of psychiatric disorders. Six representative case studies are presented and specific guidelines for the use of clonazepam are discussed.
Morishita
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Department of Psychiatry, Kawasaki Medical School, Kurashiki, Japan.
Aoki
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Watanabe
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D000328:Adult; D000368:Aged; D017109:Akathisia, Drug-Induced / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D000927:Anticonvulsants / Q000008:administration & dosage* / Q000009:adverse effects; D001714:Bipolar Disorder / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D002998:Clonazepam / Q000008:administration & dosage* / Q000009:adverse effects; D003702:Delusions / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D004359:Drug Therapy, Combination; D005260:Female; D018757:GABA Modulators / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D008875:Middle Aged; D011619:Psychotropic Drugs / Q000008:administration & dosage* / Q000009:adverse effects; D012563:Schizophrenia, Paranoid / Q000175:diagnosis / Q000188:drug therapy / Q000523:psychology; D016896:Treatment Outcome
D000927:Anticonvulsants; D018757:GABA Modulators; D011619:Psychotropic Drugs; D002998:Clonazepam