As-triazine derivatives with potential therapeutic action. XXVI. Syntheses of 5-substituted-6-azauracil acyclonucleosides.
5-Substituted 6-azauracils were alkylated with (2-acetoxyethoxy)methly bromide to give protected acyclic nucleosides which were protected to afford acyclonucleosides of 5-substituted 6-azauracils. Their structures have been established by the UV and 1H-NMR spectra and by elemental analysis.
Chemical Pharmaceutical Research Institute, Bucharest, Romania.
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Cristescu
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Czobor
D000998:Antiviral Agents / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D014227:Triazines / Q000138:chemical synthesis* / Q000737:chemistry* / Q000494:pharmacology; D014498:Uracil / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
D000998:Antiviral Agents; D014227:Triazines; D014498:Uracil; C100248:azauracil