Combinatorial chemistry using polymer-supported reagents.
During the past several years, the field of combinatorial chemistry has expanded to include not only solid- and solution-phase methods for expedited compound synthesis, but also hybrid approaches that span these two extremes. In particular, polymer-supported reagents have emerged as useful combinatorial chemistry tools for the discovery and optimization of new pharmaceutical leads.
Lilly Research Laboratories, Lilly Corporate Center, Eli Lilly and Company Indianapolis, IN 46285, USA. Kaldor@lilly.com
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D002625:Chemistry, Organic; D007202:Indicators and Reagents / Q000737:chemistry*; D055601:Organic Chemistry Phenomena; D011108:Polymers / Q000737:chemistry*
D007202:Indicators and Reagents; D011108:Polymers