[Monoclonal antibodies which recognize herpes simplex virus and their possible diagnostic application].
It is reported the obtention of monoclonal antibodies, which are capable of recognizing HSV-1 and HSV-2 viruses, by the conventional technology of cellular fusion. The monoclonal antibodies of highest positivity according to the indirect immunofluorescence technique were partially characterized. It was determined the neutralizing capacity of 2 of them (278-F7 and 70-G10), which were used to identify isolations of clinical specimens by indirect immunofluorescence. These monoclonal antibodies recognized HSV-1 up to a dilution of 1:2 560.
Instituto de Medicina Tropical Pedro Kourí, Ciudad de La Habana, Cuba.
M
M
Pupo Antúnez
C
C
Hermida Díaz
L
L
Morier Díaz
S
S
García Infante
S
S
Resik Aguirre
D000818:Animals; D000914:Antibodies, Viral / Q000276:immunology*; D000918:Antibody Specificity; D002522:Chlorocebus aethiops; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006561:Herpes Simplex / Q000175:diagnosis*; D006801:Humans; D006825:Hybridomas / Q000276:immunology; D051379:Mice; D008807:Mice, Inbred BALB C; D018139:Simplexvirus / Q000276:immunology*; D014709:Vero Cells
D000914:Antibodies, Viral