[The effect of treatment on the course of invasion by Hymenolepis nana and the state of its population in white mice].
Leukinferon administered before infection affects the development of a Hymenolepis nana population in the murine intestine: in rodents, its defective forms predominate over mature ones. Leukinferon caused cell prestimulation in the immune system and activation of nonspecific defense factors. The cytokine properties of the agent appear to have an impact on parasitic growth and development by leading to formation of defective Hymenolepis forms directly and indirectly through the host's body due to the prestimulation and enhancement of nonspecific defense. There may be a concurrent influence of these factors on H. nana embryos in the murine intestine.
N S
NS
Malysheva
D000276:Adjuvants, Immunologic / Q000627:therapeutic use; D000818:Animals; D000923:Anticestodal Agents / Q000627:therapeutic use; D002733:Chlorophenols / Q000627:therapeutic use; D016207:Cytokines / Q000627:therapeutic use; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D004359:Drug Therapy, Combination; D006925:Hymenolepiasis / Q000188:drug therapy* / Q000469:parasitology / Q000517:prevention & control; D006926:Hymenolepis / Q000187:drug effects / Q000302:isolation & purification; D007370:Interferon Type I / Q000627:therapeutic use; D007421:Intestine, Small / Q000469:parasitology; D007814:Larva / Q000187:drug effects; D051379:Mice; D013997:Time Factors
D000276:Adjuvants, Immunologic; D000923:Anticestodal Agents; D002733:Chlorophenols; D016207:Cytokines; D004338:Drug Combinations; D007370:Interferon Type I; C062252:leukinferon; C003642:trichlorophene