Inhibition of amyloid formation: a strategy to delay the onset of Alzheimer's disease.
Converging evidence suggests that the formation of amyloid plaques may play a central role in the pathogenesis of Alzheimer's disease and that blocking amyloid formation may be an effective therapeutic strategy.
Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA. lansbury@cnd.bwh.harvard.edu
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Lansbury
D000544:Alzheimer Disease / Q000188:drug therapy* / Q000378:metabolism; D016229:Amyloid beta-Peptides / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006801:Humans; D058225:Plaque, Amyloid / Q000187:drug effects* / Q000378:metabolism
D016229:Amyloid beta-Peptides