Morphine accelerates the progression of sepsis in an experimental sepsis model.
Roy
S
S
Department of Pharmacology, Veterans Administration Medical Center, Minneapolis, Minnesota, USA.
Cain
K J
KJ
Charboneau
R G
RG
Barke
R A
RA
D000818:Animals; D002455:Cell Division / Q000187:drug effects; D004195:Disease Models, Animal; D018450:Disease Progression; D007107:Immune System / Q000187:drug effects; D007166:Immunosuppressive Agents / Q000494:pharmacology*; D007375:Interleukin-1 / Q000235:genetics / Q000378:metabolism; D007376:Interleukin-2 / Q000096:biosynthesis; D008070:Lipopolysaccharides; D051379:Mice; D008813:Mice, Inbred ICR; D009020:Morphine / Q000494:pharmacology*; D009929:Organ Size / Q000187:drug effects; D010641:Phenotype; D010902:Pituitary Gland / Q000187:drug effects / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D018805:Sepsis / Q000139:chemically induced / Q000276:immunology*; D016019:Survival Analysis; D013950:Thymus Gland / Q000166:cytology / Q000187:drug effects
D007166:Immunosuppressive Agents; D007375:Interleukin-1; D007376:Interleukin-2; D008070:Lipopolysaccharides; D012333:RNA, Messenger; D009020:Morphine