Laparoscopic surgery for pheochromocytoma: adrenalectomy, partial resection, excision of paragangliomas.
OBJECTIVE
Surgical treatment of pheochromocytoma includes adrenalectomy, adrenal sparing surgery and excision of extraadrenal paragangliomas. We report our experience using laparoscopy for these procedures.


METHODS
Between June 1992 and November 1997, 19 patients underwent laparoscopic surgery for pheochromocytoma. Of the patients 14 had solitary tumors, and 4 presented with bilateral pheochromocytomas and 1 or 2 additional paragangliomas. In 1 patient a recurrent pheochromocytoma was found in the contralateral adrenal following previous right adrenalectomy. One patient each had myocardiopathy, amaurosis and stroke secondary to severe hypertension. Two patients were pregnant.


RESULTS
All solitary tumors were treated with laparoscopic adrenalectomy. Laparoscopic adrenal sparing surgery (4 cases, 2 bilateral) and bilateral adrenalectomy (1) were performed for multiple familial pheochromocytoma, and all paragangliomas were excised simultaneously. The pregnant patients underwent surgery at 16 and 20 weeks of gestation, respectively. All procedures were completed as planned. The rate of minor intraoperative and postoperative complications was 11% and 16%, respectively, and there were no major complications. In all patients the catecholamine levels returned to normal and no residual tumors were found at followup. None of the patients undergoing partial resection required steroid replacement therapy.


CONCLUSIONS
In experienced hands, laparoscopic surgery for solitary and multiple pheochromocytoma and paraganglioma is feasible and safe, and does not increase the specific risks associated with pheochromocytoma surgery.
Department of Urology, University of Innsbruck, Austria.
G
G
Janetschek
G
G
Finkenstedt
R
R
Gasser
U G
UG
Waibel
R
R
Peschel
G
G
Bartsch
H P
HP
Neumann
D000310:Adrenal Gland Neoplasms / Q000235:genetics / Q000601:surgery*; D000311:Adrenal Glands / Q000601:surgery; D000315:Adrenalectomy / Q000009:adverse effects / Q000379:methods*; D000328:Adult; D000368:Aged; D001766:Blindness / Q000209:etiology; D009202:Cardiomyopathies / Q000150:complications; D002395:Catecholamines / Q000032:analysis; D002561:Cerebrovascular Disorders / Q000209:etiology; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000150:complications; D007431:Intraoperative Complications; D010535:Laparoscopy / Q000009:adverse effects / Q000379:methods; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D010235:Paraganglioma / Q000601:surgery*; D010673:Pheochromocytoma / Q000235:genetics / Q000601:surgery*; D011183:Postoperative Complications; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000601:surgery; D012449:Safety
D002395:Catecholamines