Dual isotope SPECT in malignant Jacod's syndrome.
A case is presented of metastatic tumor causing Jacod's syndrome: total ophthalmoplegia, blindness, and trigeminal neuralgia. Abnormal soft tissue invading the orbital apex, anterior clinoid process, and cavernous sinus was difficult to assess by CT and MRI, but dual-isotope SPECT including Tc-99m HMDP bone imaging and Tl-201 tumor imaging strongly suggested that the cause of this rare syndrome was a small metastatic tumor. Although the therapeutic effect was also difficult to assess by anatomic imaging alone, dual-isotope SPECT after radiation therapy showed a decline of tumor viability.
Department of Radiology, Kochi Medical School, Japan.
M
M
Fukumoto
N
N
Tsuboi
N
N
Yoshimura
A
A
Kurohara
D
D
Yoshida
T
T
Inomata
S
S
Yoshida
D000368:Aged; D001766:Blindness / Q000000981:diagnostic imaging*; D002289:Carcinoma, Non-Small-Cell Lung / Q000000981:diagnostic imaging* / Q000532:radiotherapy / Q000556:secondary; D002426:Cavernous Sinus / Q000000981:diagnostic imaging; D005500:Follow-Up Studies; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D009886:Ophthalmoplegia / Q000000981:diagnostic imaging*; D009918:Orbital Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D019275:Radiopharmaceuticals; D019292:Skull Base Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy / Q000556:secondary; D013100:Sphenoid Bone / Q000000981:diagnostic imaging; D013577:Syndrome; D013669:Technetium Tc 99m Medronate / Q000031:analogs & derivatives*; D013794:Thallium Radioisotopes; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods*; D014057:Tomography, X-Ray Computed; D014277:Trigeminal Neuralgia / Q000000981:diagnostic imaging*
D019275:Radiopharmaceuticals; D013794:Thallium Radioisotopes; C024226:technetium Tc 99m hydroxymethylene diphosphonate; D013669:Technetium Tc 99m Medronate