Comparative antibacterial and antifungal effects of some phenolic compounds.
The antimicrobial potential of eight phenolic compounds isolated from olive cake was tested against the growth of Escherichia coli, Klebsiella pneumoniae, Bacillus cereus, Aspergillus flavus and Aspergillus parasiticus. The phenolic compounds included p-hydroxy benzoic, vanillic, caffeic, protocatechuic, syringic, and p-coumaric acids, oleuropein and quercetin. Caffeic and protocatechuic acids (0.3 mg/ml) inhibited the growth of E. coli and K. pneumoniae. The same compounds apart from syringic acid (0.5 mg/ml) completely inhibited the growth of B. cereus. Oleuropein, and p-hydroxy benzoic, vanillic and p-coumaric acids (0.4 mg/ml) completely inhibited the growth of E. coli, K. pneumoniae and B. cereus. Vanillic and caffeic acids (0.2 mg/ml) completely inhibited the growth and aflatoxin production by both A. flavus and A. parasiticus, whereas the complete inhibition of the moulds was attained with 0.3 mg/ml p-hydroxy benzoic, protocatechuic, syringic, and p-coumaric acids and quercetin.
National Centre for Radiation Research and Technology, Nasr City, Cairo, Egypt.
N H
NH
Aziz
S E
SE
Farag
L A
LA
Mousa
M A
MA
Abo-Zaid
D016604:Aflatoxin B1 / Q000096:biosynthesis; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology; D001230:Aspergillus / Q000187:drug effects* / Q000254:growth & development / Q000378:metabolism; D001231:Aspergillus flavus / Q000187:drug effects / Q000254:growth & development / Q000378:metabolism; D001409:Bacillus cereus / Q000187:drug effects / Q000254:growth & development; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D002109:Caffeic Acids / Q000494:pharmacology; D002851:Chromatography, High Pressure Liquid; D003373:Coumaric Acids / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects / Q000254:growth & development; D005638:Fruit / Q000737:chemistry*; D005707:Gallic Acid / Q000031:analogs & derivatives / Q000494:pharmacology; D062385:Hydroxybenzoates / Q000494:pharmacology; D057888:Iridoid Glucosides; D039823:Iridoids; D007711:Klebsiella pneumoniae / Q000187:drug effects / Q000254:growth & development; D010226:Parabens / Q000494:pharmacology; D010636:Phenols / Q000494:pharmacology*; D011422:Propionates; D011714:Pyrans / Q000494:pharmacology; D011794:Quercetin / Q000494:pharmacology; D014641:Vanillic Acid / Q000494:pharmacology
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D000975:Antioxidants; D002109:Caffeic Acids; D003373:Coumaric Acids; D062385:Hydroxybenzoates; D057888:Iridoid Glucosides; D039823:Iridoids; D010226:Parabens; D010636:Phenols; D011422:Propionates; D011714:Pyrans; C002769:oleuropein; C009091:protocatechuic acid; D005707:Gallic Acid; D011794:Quercetin; D016604:Aflatoxin B1; C001945:syringic acid; D014641:Vanillic Acid; C495469:p-coumaric acid; C038193:4-hydroxybenzoic acid; C040048:caffeic acid