Acute or chronic administration of okadaic acid to rats induces brain damage rather than Alzheimer-like neuropathology.
Research Institute Neurosciences Free University, Medical Faculty, Department of Pharmacology, Amsterdam, The Netherlands.
A M
AM
Van Dam
J G
JG
Bol
R
R
Binnekade
F L
FL
van Muiswinkel
D000544:Alzheimer Disease / Q000139:chemically induced* / Q000473:pathology; D000818:Animals; D001925:Brain Damage, Chronic / Q000139:chemically induced* / Q000473:pathology; D004791:Enzyme Inhibitors / Q000008:administration & dosage / Q000633:toxicity*; D007276:Injections, Intraventricular; D019319:Okadaic Acid / Q000008:administration & dosage / Q000633:toxicity*; D051381:Rats; D017208:Rats, Wistar
D004791:Enzyme Inhibitors; D019319:Okadaic Acid