Adenosine receptors: new opportunities for future drugs.
This review summarises current knowledge on adenosine receptors, an important G protein-coupled receptor. The four known adenosine receptor subtypes A1, A2A, A2B, and A3 are discussed with special reference to the opportunities for drug development.
Poulsen
S A
SA
Queensland Pharmaceutical Research Institute, Griffith University, Brisbane, Australia.
Quinn
R J
RJ
D000241:Adenosine / Q000378:metabolism / Q000502:physiology; D000818:Animals; D019204:GTP-Binding Proteins / Q000378:metabolism*; D006801:Humans; D008024:Ligands; D008958:Models, Molecular; D004364:Pharmaceutical Preparations / Q000737:chemistry / Q000378:metabolism; D018047:Receptors, Purinergic P1 / Q000737:chemistry / Q000187:drug effects* / Q000502:physiology; D013329:Structure-Activity Relationship
D008024:Ligands; D004364:Pharmaceutical Preparations; D018047:Receptors, Purinergic P1; D019204:GTP-Binding Proteins; D000241:Adenosine