Increased proliferation of myoblasts after cyclic plasma perfusion of tumor-bearing rabbits.
Rabbits implanted with VX2 carcinoma and treated by cyclic plasma perfusion showed lower weight loss and longer survival than untreated rabbits. The urinary 3-methylhistidine/creatine ratio was less elevated in the treated rabbits than in the untreated rabbits. Myoblasts from untreated rabbits with VX2 carcinoma showed lower proliferation than those from normal rabbits, while those from rabbits treated by cyclic plasma perfusion showed intermediate proliferation. Furthermore, the DNA synthesis rate of myoblasts from treated rabbits was much better maintained than in the case of untreated rabbits.
Department of Obstetrics and Gynecology, Osaka City University Medical School.
S
S
Nakata
O
O
Ishiko
K
K
Honda
K
K
Hirai
M
M
Deguchi
S
S
Ogita
D000818:Animals; D001835:Body Weight; D002277:Carcinoma / Q000401:mortality / Q000473:pathology*; D002455:Cell Division; D004247:DNA / Q000096:biosynthesis; D008297:Male; D009132:Muscles / Q000166:cytology*; D009368:Neoplasm Transplantation; D010477:Perfusion; D010949:Plasma; D011817:Rabbits; D013997:Time Factors; D014407:Tumor Cells, Cultured
D004247:DNA