[Blood cell count, sodium, potassium, calcium, osmolality and viscosity during pediatric angiocardiography with ioxaglate].
OBJECTIVE
Children's blood changes during angiocardiography may not be only due to the contrast media (CM).


METHODS
We studied the presence and severity of changes in those parameters in 35 pediatric patients undergoing angiocardiography with ioxaglate aiming to identify independent variable responsible for those changes. Blood samples were taken at the beginning of the procedure (SI), at the end (S2) and two hours later (S3).


RESULTS
Hematocrit: S1 = 47.3 +/- 6.9%; S2 = 40.7 +/- 7.4% (p < 0.001), (related to the CM volume r=0.37, (p < 0.05). Hemoglobin: S1 = 15 +/- 2.1g%; S2 = 13.2 +/- 2.4g% (p < 0.001), and S3 = 12.7 +/- 2.5g% (NS). White blood cell count: S1 = 7940 +/- 3040 leukocytes/mm3; S2 = 6950 +/- 2700/mm3 (NS); S3 = 10830 +/- 4690 leukocytes/mm3 (p < 0.001). Procedure duration (r = 0.83, p < 0.05) and 5% glucose fluid given between S2 and S3 (r = 0.49, p < 0.05) were isolated. Sodium: S1 = 134.5 +/- 0.4mEq/L, S2 = 130.7 +/- 0.4mEq/L (p < 0.001) (due to 5% glucose fluid injected, r = 0.61, p < 0.01). Potassium: S1 = 4.22 +/- 0.45mEq/L, S2 = 300.6 +/- 13.3mOsm/kg (p < 0.001). Calcium: S1 = 9.13 +/- 1.03mg%; S2 = 8.4 +/- 0.91 mg/dL. (related to the CM, r = 0.43, p < 0.01.) Osmolality: S1= 293.3 +/- 12.5mOsm/kg; S2 = 3.83 +/- 0.4mEq/L (p<0.001). Viscosity: S1 = 3.36 +/- 0.81; S2 = 3.09 +/- 0.74 (p < 0.01); S3 = 3.87 +/- 0.89, p < 0.001. There was an indirect linear regression with the CM.


CONCLUSIONS
There were profound differences among the dependent variables observed but the ioxaglate was partially related to changes in hematocrit/hemoglobin, total calcium and viscosity. We failed to demonstrate significant regression coefficient between CM and changes in leukocytes, sodium, potassium, and osmolality.
Moura
M R
MR
Instituto de Cardiologia do Rio Grande do Sul/Fundação Universitária de Cardiologia.
Leboute
F
F
Gottschall
C A
CA
D000790:Angiocardiography; D001772:Blood Cell Count; D001809:Blood Viscosity; D002118:Calcium / Q000097:blood*; D002648:Child; D002675:Child, Preschool; D003287:Contrast Media / Q000009:adverse effects*; D005260:Female; D006330:Heart Defects, Congenital / Q000097:blood; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007485:Ioxaglic Acid / Q000009:adverse effects*; D008297:Male; D009994:Osmolar Concentration; D011188:Potassium / Q000097:blood*; D011446:Prospective Studies; D012964:Sodium / Q000097:blood*
D003287:Contrast Media; D012964:Sodium; D011188:Potassium; D002118:Calcium; D007485:Ioxaglic Acid