[Pancreas carcinoid with extensive liver metastasis--simultaneous excision].
This case report describes an unusually large islet cell tumour of the pancreas presenting clinically with extensive metastases in the liver. The patient involved was a 55-year-old woman. The leading symptom was severe, hardly tractable diarrhoea. Histological examination including immunohistochemistry and measurements of the proliferation index revealed a probable malignant Vipoma of low grade. It was treated by simultaneous R0 resection of the tumour masses; the postoperative course was unremarkable. This outcome is seen as a strong argument in favour of a radical surgical approach even if there is significant metastatic disease in the liver. The advantage of intraoperative ultrasound is discussed along with aspects of tumour classification and alternative therapeutic modalities.
Oettinger
W
W
Abteilung für Allgemein-, Unfall- und Gafässchirurgie.
Schneider
C
C
Franzen
S
S
Makuuchi
M
M
D005260:Female; D006498:Hepatectomy; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000601:surgery; D008303:Malignant Carcinoid Syndrome / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D010179:Pancreas / Q000473:pathology; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000601:surgery*; D014057:Tomography, X-Ray Computed; D003969:Vipoma / Q000175:diagnosis / Q000473:pathology / Q000556:secondary* / Q000601:surgery