[Association of amyotrophic lateral sclerosis with scleroderma. Study of 2 cases].
We report a clinical association of diffuse scleroderma and amyotrophic lateral sclerosis (ALS) in two patients. Scleroderma was diagnosed on skin, digestive, osteoarticular, pulmonary lesions and inflammatory syndrome. ALS was suspected on the association of diffuse amyotrophy, fasciculations, pyramidal tract involvement and electrophysiological data. Chronic medulla ischemia and or immune abnormalities are proposed as potential pathological mechanisms for ALS but fortuitous association can not be excluded.
Service de Neurologie, Hôpital Militaire d'Instruction Mohamed V, Rabat, Maroc.
H
H
Ouhabi
A
A
Bourazza
A
A
Rouimi
N
N
Boutaleb
R
R
Mosseddaq
D000690:Amyotrophic Lateral Sclerosis / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000150:complications* / Q000175:diagnosis