[The effect of cholisorb on liver exocrine function].
The effect of cholisorb and its salt (Na and K) forms on the external secretion of the liver was studied. The cholagogic effect of the H-form of cholisorb and its salt forms was demonstrated in dog experiments. The effect of the H-form proved to be stronger. This effect was associated with decreased absorption of bile acids and cholesterol in the intestine and disturbed hepato-intestinal biliary cycle as a result of which adaptation mechanisms directed at restoration of this cycle are apparently switched on.
Degtiarev
A N
AN
Institute of Physico-Chemical Medicine, Ministry of Public Health of the Russian Federation, Moscow, Russia.
Mikhaĭlovskaia
A Iu
AIu
Vasilevskaia
L S
LS
Sergienko
V I
VI
D000818:Animals; D001285:Atropine / Q000494:pharmacology; D001646:Bile / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism; D002756:Cholagogues and Choleretics / Q000008:administration & dosage / Q000494:pharmacology*; D004285:Dogs; D008099:Liver / Q000187:drug effects* / Q000378:metabolism*; D008298:Maleates / Q000008:administration & dosage / Q000494:pharmacology*; D011205:Povidone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology
D002756:Cholagogues and Choleretics; D008298:Maleates; C114335:maleic acid-vinylpyrrolidone copolymer; D001285:Atropine; D011205:Povidone