Plasmodium vivax: rapid detection by polymerase chain reaction and restriction fragment length polymorphism of the key mutation in dihydrofolate reductase-thymidylate synthase gene associated with pyrimethamine resistance.
Centre de Génétique Moléculaire, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France. Rachida.Tahar@cgm.cnrs-gif.fr
R
R
Tahar
P E
PE
de Pecoulas
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A
Mazabraud
L K
LK
Basco
D000595:Amino Acid Sequence; D000818:Animals; D000962:Antimalarials / Q000494:pharmacology*; D001483:Base Sequence; D003062:Codon / Q000737:chemistry / Q000235:genetics; D016054:DNA, Protozoan / Q000737:chemistry; D004351:Drug Resistance / Q000235:genetics; D005838:Genotype; D006801:Humans; D016780:Malaria, Vivax / Q000453:epidemiology / Q000469:parasitology; D008969:Molecular Sequence Data; D010966:Plasmodium vivax / Q000187:drug effects / Q000201:enzymology / Q000235:genetics*; D017354:Point Mutation; D016133:Polymerase Chain Reaction; D012150:Polymorphism, Restriction Fragment Length; D011739:Pyrimethamine / Q000494:pharmacology*; D015203:Reproducibility of Results; D016415:Sequence Alignment; D013762:Tetrahydrofolate Dehydrogenase / Q000235:genetics*; D013940:Thymidylate Synthase / Q000235:genetics*
D000962:Antimalarials; D003062:Codon; D016054:DNA, Protozoan; D013762:Tetrahydrofolate Dehydrogenase; D013940:Thymidylate Synthase; D011739:Pyrimethamine