[Risks in late diagnosis of retinoblastoma and their prevention].
The study of the therapy of 57 patients with retinoblastoma and their 30-year follow-up a very significant problem of the delayed assessment of the diagnosis in this disease. The age of patients at the point of assessment of the diagnosis was delayed in average for 3 months after the appearance of first symptoms being especially leucocoria and strabismus, in hereditary Rb it yielded 10 months and in non-hereditary 36 months. The study emphasizes the risks of achieving lower therapeutic success rates and higher lethality in patients in very advanced stages of the disease. An improvement in parental care is assumed to represent a significant preventive measure against the late assessment of the diagnosis. The authors suggest an improvement in erudition of regional paediatrists together with fast provision of clinical care with the use of all diagnostic and therapeutic possibilities provided by modern medicine. (Fig. 4, Ref. 6.)
Klinika detskej oftalmológie Lekárskej fakulty Univerzity Komenského v Bratislave, Slovakia.
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Gerinec
D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D011379:Prognosis; D019572:Retinal Neoplasms / Q000175:diagnosis* / Q000628:therapy; D012175:Retinoblastoma / Q000175:diagnosis* / Q000628:therapy; D012307:Risk Factors; D013997:Time Factors; D017211:Treatment Failure