Experimental transmission of dermal sarcoma to the sauger Stizostedion canadense.
Walleye dermal sarcoma virus (WDSV) has been identified as the causative agent of a benign neoplasia of walleye Stizostedion vitreum, walleye dermal sarcoma (WDS). We conducted an experimental transmission regimen to determine if WDSV is capable of inducing dermal sarcoma in the closely related sauger S. canadense. Nearly all of young-of-the-year saugers (96%) inoculated with filtrates of spring-collected tumors developed dermal sarcomas, while all of the inoculated walleyes developed tumors. Most of the sauger tumors were limited to the skin, but invasive tumors, similar to those previously observed in experimental walleyes, were observed in some fish.
Holzschu
D L
DL
Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA.
Wooster
G A
GA
Bowser
P R
PR
D000818:Animals; D004279:DNA, Viral / Q000032:analysis; D005393:Fish Diseases / Q000473:pathology / Q000635:transmission* / Q000821:virology; D005618:Fresh Water; D015683:Gene Products, gag / Q000235:genetics; D007087:Illinois; D018482:Muscle, Skeletal / Q000473:pathology; D009361:Neoplasm Invasiveness; D009518:New York; D010473:Perciformes; D016133:Polymerase Chain Reaction / Q000662:veterinary; D012190:Retroviridae / Q000235:genetics / Q000302:isolation & purification; D012192:Retroviridae Infections / Q000473:pathology / Q000635:transmission / Q000662:veterinary*; D012878:Skin Neoplasms / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D013131:Spine / Q000473:pathology; D014412:Tumor Virus Infections / Q000473:pathology / Q000635:transmission / Q000662:veterinary*
D004279:DNA, Viral; D015683:Gene Products, gag