Reproducibility of automatic standard digital analysis of lens opacities.
OBJECTIVE
This study was designed to assess the repeatability of the standard analysis of images taken with the Nidek EAS-1000 anterior segment analysis system (Nidek Co. Ltd, Japan).


METHODS
Participants in a large clinical trial (the vitamin E, cataract and age-related maculopathy study) were asked to undergo two independent examinations to assess the repeatability of primary outcome measures. After pupil dilatation to at least 6.5 mm, 104 eyes were photographed using the retro-illumination method and the slit-beam method.


RESULTS
Intra-class correlation coefficients were: slit images, R = 0.982; retro-illumination images, R = 0.978.


CONCLUSIONS
Repeatability of measurement of lens opacity from EAS-1000 images using automated standard analysis was high.
Monash University, Department of Epidemiology and Preventive Medicine, Prahran, Victoria, Australia. sinead.garrett@med.monash.edu.au
S K
SK
Garrett
L D
LD
Robman
C A
CA
McCarty
A P
AP
Thomas
J J
JJ
McNeil
H R
HR
Taylor
D000368:Aged; D002386:Cataract / Q000145:classification* / Q000473:pathology; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000592:standards*; D008297:Male; D010781:Photography / Q000592:standards; D015203:Reproducibility of Results