Adenosine receptors: new opportunities for future drugs.
This review summarises current knowledge on adenosine receptors, an important G protein-coupled receptor. The four known adenosine receptor subtypes A1, A2A, A2B, and A3 are discussed with special reference to the opportunities for drug development.
Queensland Pharmaceutical Research Institute, Griffith University, Brisbane, Australia.
S A
SA
Poulsen
R J
RJ
Quinn
D000241:Adenosine / Q000378:metabolism / Q000502:physiology; D000818:Animals; D019204:GTP-Binding Proteins / Q000378:metabolism*; D006801:Humans; D008024:Ligands; D008958:Models, Molecular; D004364:Pharmaceutical Preparations / Q000737:chemistry / Q000378:metabolism; D018047:Receptors, Purinergic P1 / Q000737:chemistry / Q000187:drug effects* / Q000502:physiology; D013329:Structure-Activity Relationship
D008024:Ligands; D004364:Pharmaceutical Preparations; D018047:Receptors, Purinergic P1; D019204:GTP-Binding Proteins; D000241:Adenosine