Antimicrobial susceptibility of subgingival bacterial flora in cats with gingivitis.
The aerobic and anaerobic flora from gingival pockets of 40 cats with established gingivitis were cultured. The susceptibility of each isolate to four antimicrobial agents currently approved for use in cats (amoxicillin-clavulanic acid; clindamycin; cefadroxil; enrofloxacin) was determined. Amoxicillin-clavulanic acid (Clavamox) had the highest in-vitro susceptibility against all isolates (92%) and all anaerobes (99% [co-equal with clindamycin]) tested; enrofloxacin (Baytril) had the highest in-vitro susceptibility against all aerobes (90%) tested.
Harvey
C E
CE
Veterinary Hospital of the University of Pennsylvania, Philadelphia 19104, USA.
Thornsberry
C
C
Miller
B R
BR
Shofer
F S
FS
D019980:Amoxicillin-Potassium Clavulanate Combination / Q000494:pharmacology / Q000627:therapeutic use; D000704:Analysis of Variance; D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology / Q000627:therapeutic use; D000890:Anti-Infective Agents; D001420:Bacteria, Aerobic / Q000187:drug effects; D001421:Bacteria, Anaerobic / Q000187:drug effects; D002371:Cat Diseases / Q000188:drug therapy / Q000382:microbiology*; D002415:Cats; D002434:Cefadroxil / Q000494:pharmacology / Q000627:therapeutic use; D002981:Clindamycin / Q000494:pharmacology / Q000627:therapeutic use; D000077422:Enrofloxacin; D024841:Fluoroquinolones; D005891:Gingivitis / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D008826:Microbial Sensitivity Tests / Q000662:veterinary; D010514:Periodontal Pocket / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D015363:Quinolones / Q000494:pharmacology / Q000627:therapeutic use; D018709:Statistics, Nonparametric
D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015363:Quinolones; D002434:Cefadroxil; D000077422:Enrofloxacin; D002981:Clindamycin; D019980:Amoxicillin-Potassium Clavulanate Combination