Epidural abscess complicating epidural anesthesia and analgesia. An analysis of the literature.
BACKGROUND
Epidural abscess is a serious complication of epidural block. Because of its low incidence, the risk factors and the symptoms and cause of epidural abscess related to epidural anesthesia and analgesia are not well known by anesthesiologists.


METHODS
A computer-assisted search of the literature on epidural catheter-related abscess was performed to describe the clinical course and bacteriology of this complication, to determine possible risk factors, and to assess the index of suspicion among physicians.


RESULTS
Forty-two patients with a catheter-related epidural abscess were identified. Only in 15 patients was the correct diagnosis considered initially. The time from insertion of the epidural catheter to symptoms varied between 1 and 60 d. Initial symptoms included back pain, fever, and leukocytosis. The time from symptoms to treatment was a few hours to 108 d. Interval from first symptoms to treatment was significantly longer in patients with persistent neurologic deficits compared with patients who completely recovered. Staphylococcus aureus was the most common etiologic agent. Outcome was reported in 39 patients, but only 19 made a full recovery.


CONCLUSIONS
The index of suspicion among anesthesiologists, other physicians and nurses taking care of patients with epidural catheters must be increased for this complication; this should shorten the interval from symptoms to treatment and lower the incidence of neurological sequelae.
Department of Anesthesia, Kantonsspital, University of Basel, Switzerland.
C H
CH
Kindler
M D
MD
Seeberger
S E
SE
Staender
D000038:Abscess / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D015360:Analgesia, Epidural / Q000009:adverse effects*; D000767:Anesthesia, Epidural / Q000009:adverse effects*; D006801:Humans; D012307:Risk Factors; D013118:Spinal Cord Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy