Cavitary pulmonary metastases of gallbladder cancer.
We report a case of multiple cavitary pulmonary metastases of gallbladder cancer. Radiologically, every cavity displayed a very thin wall containing only air inside. The postmortem histopathological examination showed that: (1) the cavities were surrounded by normal alveoli; (2) these walls were composed mostly of adenocarcinoma cells; (3) necrotic or mucous substance was sparse in the cavity space; (4) cancer cells infiltrated along the surface of the alveolar septa, and (5) the morphology of the cancer cells of the gallbladder and the lung was the same. It seemed likely that the thin-walled cavities in the lung might result from central breakdown of the tumor and subsequent expectoration of debris through the connected airways.
3rd Department of Internal Medicine, Aichi Medical University, Japan.
K
K
Baba
T
T
Hattori
I
I
Koishikawa
T
T
Kamiya
A
A
Noda
T
T
Kobayashi
K
K
Ikuta
D000230:Adenocarcinoma / Q000473:pathology / Q000556:secondary*; D005704:Gallbladder / Q000473:pathology; D005706:Gallbladder Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008168:Lung / Q000473:pathology; D008175:Lung Neoplasms / Q000473:pathology / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D009336:Necrosis; D014463:Ultrasonography