Pituitary apoplexy in an adolescent with prolactin-secreting adenoma.
A 14.8-year-old girl was treated with bromocriptine for a prolactin-secreting adenoma. She suddenly developed headaches, vomiting, fever and meningeal syndrome. This was associated with corticotropin, thyrotropin and gonadotropin deficiencies. Magnetic resonance imaging showed peripheral enhancement and a central hyposignal suggesting intra-adenoma hemorrhage and then disappearance of the adenoma. Hydrocortisone was initiated in emergency to prevent any risk to life.
Pinto
G
G
Pediatric Endocrinology Unit, Université Paris V and Hôpital Necker-Enfants Malades, Assistance-Publique-Hôpitaux de Paris, France.
Zerah
M
M
Trivin
C
C
Brauner
R
R
D000293:Adolescent; D001971:Bromocriptine / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006854:Hydrocortisone / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D010899:Pituitary Apoplexy / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D010911:Pituitary Neoplasms / Q000150:complications* / Q000188:drug therapy; D015175:Prolactinoma / Q000150:complications* / Q000188:drug therapy
D001971:Bromocriptine; D006854:Hydrocortisone