Indication for isolated hyperthermic liver perfusion: a surgeon's view.
Isolated hyperthermic liver perfusion is a transitional therapy, i.e. a therapy between evidence based, standard therapy and experimental therapy. It appears to provide distinct benefits in a number of situations but the scientific evidence is still incomplete. In our view the present indications for use of isolated hyperthermic perfusion of the liver are: to gain more knowledge; nonresectable liver metastases without proven extrahepatic growth from: uveal melanoma, colorectal carcinoma, and ovarian cancer; symptoms related to hepatic metastases from endocrine tumors. A multicenter study aimed at gaining more knowledge is recommended.
Scherstén
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University of Göteborg, Sahlgrenska Hospital, Department of Surgery, Sweden.
D010478:Chemotherapy, Cancer, Regional Perfusion / Q000379:methods*; D004644:Emotions; D019317:Evidence-Based Medicine; D013502:General Surgery; D019456:Health Transition; D006805:Human Experimentation; D006801:Humans; D006979:Hyperthermia, Induced