Felodipine-induced gingival hyperplasia.
Felodipine is a calcium channel blocking agent used in the management of hypertension and angina. We report a case of gingival hyperplasia in a patient with chronic use of this drug. Gingival changes occurred soon after initiation of felodipine and improved upon its discontinuation. The clinical characteristics, inciting agents, proposed pathogenetic mechanisms, as well as prevention and treatment of drug-induced gingival hyperplasia are briefly reviewed.
Dermatology Service, Walter Reed Army Medical Center, Washington, DC., USA.
P C
PC
Young
G W
GW
Turiansky
P
P
Sau
M D
MD
Liebman
P M
PM
Benson
D000368:Aged; D002121:Calcium Channel Blockers / Q000009:adverse effects*; D015736:Felodipine / Q000009:adverse effects*; D005260:Female; D005885:Gingival Hyperplasia / Q000139:chemically induced*; D006801:Humans
D002121:Calcium Channel Blockers; D015736:Felodipine