What are guanosine triphosphate-binding proteins doing in mitochondria?
The discovery of GTP-binding proteins in mitochondria is a recent event. These regulatory proteins may be participating in membrane fusion and thereby playing important roles in the physiology of the mitochondrion. So far, it has been proposed that GTP-binding protein mediated membrane fusion may be involved in protein import, steroid hormone production and mitochondrial amalgamation during spermatogenesis.
Thomson
M
M
School of Science-Biology, University of Western Sydney Nepean, PO Box 10, Kingswood, NSW 2747, Australia. m.thomson@uws.edu.au
D000818:Animals; D001692:Biological Transport; D019204:GTP-Binding Proteins / Q000378:metabolism / Q000502:physiology*; D008297:Male; D008561:Membrane Fusion / Q000502:physiology; D008928:Mitochondria / Q000378:metabolism / Q000502:physiology* / Q000648:ultrastructure; D011284:Pregnenolone / Q000096:biosynthesis; D011506:Proteins / Q000378:metabolism; D012270:Ribosomes / Q000378:metabolism; D013094:Spermatozoa / Q000502:physiology / Q000648:ultrastructure
D011506:Proteins; D011284:Pregnenolone; D019204:GTP-Binding Proteins