Drug-induced ocular cicatricial pemphigoid: a series of clinico-pathological reports.
Ocular cicatricial pemphigoid is a slowly progressive disease of mucous membranes and skin of unknown but presumed autoimmune aetiology. We describe eight cases of presumed drug-induced cicatrising conjunctival changes simulating ocular cicatricial pemphigoid, following the chronic use of topical glaucoma medication. In three of four patients who underwent conjunctival biopsy of the inferior fornix, this revealed histopathological changes similar to ocular cicatricial pemphigoid.
Butt
Z
Z
Department of Ophthalmology, Royal Victorian Eye and Ear Hospital, Melbourne, Australia.
Kaufman
D
D
McNab
A
A
McKelvie
P
P
D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D003228:Conjunctiva / Q000473:pathology; D003231:Conjunctivitis / Q000139:chemically induced* / Q000473:pathology; D005260:Female; D005901:Glaucoma / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010390:Pemphigoid, Benign Mucous Membrane / Q000139:chemically induced* / Q000473:pathology
D000959:Antihypertensive Agents