Incidence of spikes and paroxysmal rhythmic events in overnight ambulatory computer-assisted EEGs of normal subjects: a multicenter study.
The incidences of spikes and paroxysmal rhythmic events (PREs) in 10-h overnight EEGs of normal adult volunteers (n=135) were studied at 11 sites with a computer-assisted ambulatory EEG monitoring system with automatic spike and PRE detection. Spikes were evident in the overnight EEG of 1 subject (0.7%), and PREs were apparent in the overnight EEG of the same subject (0.7%). The incidences of spikes of 24 other subjects with a history of migraine and/or a family history of epilepsy were 12.5 and 13.3%, respectively. The overnight EEGs of these subjects were significantly more likely to show spikes than the overnight EEGs of subjects without migraine or a family history of epilepsy.
Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, USA.
S C
SC
Schachter
M
M
Ito
B B
BB
Wannamaker
I
I
Rak
K
K
Ruggles
F
F
Matsuo
A
A
Wilner
R
R
Jackel
F
F
Gilliam
G
G
Morris
J
J
Skantz
M
M
Sperling
J
J
Buchhalter
F W
FW
Drislane
J
J
Ives
D L
DL
Schomer
D000293:Adolescent; D000328:Adult; D000368:Aged; D000553:Ambulatory Care; D001931:Brain Mapping / Q000295:instrumentation; D002540:Cerebral Cortex / Q000503:physiopathology; D004569:Electroencephalography / Q000295:instrumentation*; D004827:Epilepsy / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology; D005071:Evoked Potentials / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008881:Migraine Disorders / Q000175:diagnosis* / Q000235:genetics / Q000503:physiopathology; D008991:Monitoring, Physiologic / Q000295:instrumentation*; D012016:Reference Values; D012815:Signal Processing, Computer-Assisted / Q000295:instrumentation*