Risks of intravenous amiodarone in neonates.
The courses of two neonates treated with intravenous amiodarone for supraventricular tachyarrhythmia, both of whom developed significant adverse effects, are reported. A 13-day-old term newborn developed hypothyroidism after 27 days of mostly intravenous amiodarone for atrioventricular reciprocating tachycardia and severe heart failure. A one-day-old, 36 weeks' gestation newborn developed electromechanical dissociation after receiving an intravenous bolus of amiodarone for rapid atrial flutter. Judicious use of amiodarone is recommended.
Department of Pediatrics, University of Alberta, Edmonton.
J
J
Gandy
N
N
Wonko
M J
MJ
Kantoch
D000367:Age Factors; D000638:Amiodarone / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D006801:Humans; D007037:Hypothyroidism / Q000139:chemically induced; D007231:Infant, Newborn; D007275:Injections, Intravenous; D013617:Tachycardia, Supraventricular / Q000188:drug therapy*
D000638:Amiodarone