Diagnosis and treatment in utero of goiter with hypothyroidism caused by iodide overload.
A fetal goiter was detected by ultrasonography in a woman receiving potassium iodide. After this medication was discontinued at 29 weeks, a fetal hypothyroidism was confirmed by cordocentesis, and two doses of levothyroxine were administered by amniocentesis. At 34 weeks repeated cordocentesis showed fetal euthyroidism and ultrasonography shrinkage of the goiter. Growth and development normal at 1 year.
Hospital Universitario Materno-Infantil Vall D'Hebron, Barcelona, Spain.
E
E
Vicens-Calvet
N
N
Potau
E
E
Carreras
J
J
Bellart
M A
MA
Albisu
A
A
Carrascosa
D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000139:chemically induced / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006042:Goiter / Q000139:chemically induced / Q000000981:diagnostic imaging*; D006801:Humans; D007037:Hypothyroidism / Q000139:chemically induced / Q000188:drug therapy; D011193:Potassium Iodide / Q000008:administration & dosage / Q000009:adverse effects*; D011247:Pregnancy; D013974:Thyroxine / Q000627:therapeutic use; D016216:Ultrasonography, Prenatal
D011193:Potassium Iodide; D013974:Thyroxine