Livedo reticularis and Raynaud's phenomenon associated with cryoglobulinaemia but not related to hepatitis C virus in an HIV-1-positive patient.
Symptomatic cryoglobulinaemia is infrequent in HIV-1-infected patients, but a few cases have been described [1-3], occasionally associated with hepatitis C virus (HCV) infection [1, 3]. These cases showed rheumatologic [1] or neurologic manifestations [2, 3], but until now no cutaneous symptoms associated with cryoglobulinaemia in HIV-infected patients have been described. We report what we believe to be the first case of cutaneous, symptomatic cryoglobulinaemia in an HIV-1-positive patient, who, in addition, was HCV-negative.
Department of Dermatology, Virgen Macarena Hospi-tal, School of Medicine of Sevilla, Ave-nida Dr Fedriani s/n, 41009 Sevilla, Spain.
M A
MA
Muñoz-Pérez
A
A
Rodriguez-Pichardo
F
F
Camacho
M A
MA
Colmenero
D000328:Adult; D003449:Cryoglobulinemia / Q000150:complications*; D005260:Female; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1; D006526:Hepatitis C; D006801:Humans; D011928:Raynaud Disease / Q000150:complications*; D017445:Skin Diseases, Vascular / Q000150:complications*