Ethambutol-induced pulmonary infiltrates with fever and skin rash: a case report.
A 55-year-old man presented with the suspicion of pulmonary tuberculosis. He was treated with isoniazid, ethambutol, rifampicin and pyrazinamide. However, he developed high fever, skin rash and pulmonary infiltrates following 10 days of treatment. The above-mentioned conditions subsided promptly after stopping ethambutol therapy and reappeared after rechallenge, marking ethambutol as the offender. To present knowledge, this is the second case of an ethambutol-induced hypersensitivity lung reaction reported in English literature.
Chien
H P
HP
Taiwan Provincial Chronic Disease Control Bureau, Taipei, ROC.
Huang
S T
ST
Yu
M C
MC
Wu
I H
IH
Lin
T P
TP
D000995:Antitubercular Agents / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D004977:Ethambutol / Q000009:adverse effects*; D005076:Exanthema / Q000139:chemically induced*; D005334:Fever / Q000139:chemically induced*; D006801:Humans; D008171:Lung Diseases / Q000139:chemically induced*; D008297:Male; D008875:Middle Aged
D000995:Antitubercular Agents; D004977:Ethambutol