Geotrichum capitatum septicaemia in neutropenic patients: case report and review of the literature.
We report a case of systemic infection with Geotrichum capitatum in a patient with acute myeloid leukaemia. Three days before death, the patient developed acute renal failure, probably caused by occlusion of glomerula with hyphae of G. capitatum. Up until now, prophylaxis and treatment of infections caused by Geotrichum capitatum have not been established. However, the prophylactic administration of high-dose itraconazole and the therapeutic use of liposomal amphotericin B are subjects of discussion.
Medizinische Klinik, Rheinische Friedrich-Wilhems-Universität Bonn, Germany.
R
R
Schiemann
A
A
Glasmacher
E
E
Bailly
R
R
Horré
E
E
Molitor
C
C
Leutner
M T
MT
Smith
R
R
Kleinschmidt
G
G
Marklein
T
T
Sauerbruch
D000208:Acute Disease; D058186:Acute Kidney Injury; D001769:Blood / Q000382:microbiology; D016469:Fungemia / Q000150:complications* / Q000188:drug therapy; D005847:Geotrichosis / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D007678:Kidney Glomerulus / Q000473:pathology; D007951:Leukemia, Myeloid / Q000150:complications*; D008002:Libya / Q000208:ethnology; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009503:Neutropenia / Q000150:complications*; D011859:Radiography; D014054:Tomography