Genes for polymorphic H1 histones are linked in the Japanese quail genome.
In a previous report (Pałyga, J., Biochem. Genet. 29, 431-445, 1991), three subtypes of erythrocyte histone H1 were found to vary in a Japanese quail population. While H1.b and H1.z histones were each represented by two electromorphs differing in apparent molecular weights, a polymorphism of histone H1.a was connected with a lack of this protein in some birds. As a genetic basis for this variability was demonstrated only in H1.b, here genetic data are provided which indicate that both H1.a and H1.z are encoded by two codominant alleles at a locus. A linkage analysis of family data in 13 quail pedigrees has revealed a significant linkage between H1.a and H1.z and between H1.b and H1.z (lod scores about 12 and 5, respectively). Thus, a gene for histone H1.z is located between H1.a and H1.b in the quail genome.
Department of Genetics, Wyzsza Szkoła Pedagogiczna, Kielce, Poland.
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Pałyga
D000483:Alleles; D000818:Animals; D003370:Coturnix / Q000097:blood / Q000235:genetics*; D004591:Electrophoresis, Polyacrylamide Gel; D004912:Erythrocytes / Q000378:metabolism; D005260:Female; D008040:Genetic Linkage; D005838:Genotype; D006657:Histones / Q000235:genetics* / Q000378:metabolism; D008126:Lod Score; D008297:Male; D011110:Polymorphism, Genetic
D006657:Histones