Chronic intrauterine pulmonary hypertension increases preproendothelin-1 and decreases endothelin B receptor mRNA expression in the ovine fetal lung.
Ivy
D D
DD
Pediatric Heart Lung Center, Department of Pediatrics, University of Colorado School of Medicine and the Children's Hospital, Denver, USA.
Le Cras
T D
TD
Horan
M P
MP
Abman
S H
SH
D000818:Animals; D002908:Chronic Disease; D004195:Disease Models, Animal; D019332:Endothelin-1; D016232:Endothelins / Q000378:metabolism*; D005315:Fetal Diseases / Q000378:metabolism*; D006976:Hypertension, Pulmonary / Q000378:metabolism*; D008168:Lung / Q000378:metabolism*; D011498:Protein Precursors / Q000378:metabolism*; D012333:RNA, Messenger / Q000378:metabolism*; D017466:Receptors, Endothelin / Q000378:metabolism*; D012756:Sheep; D014661:Vasoconstriction
D019332:Endothelin-1; D016232:Endothelins; D011498:Protein Precursors; D012333:RNA, Messenger; D017466:Receptors, Endothelin