Possible ventricular late potentials in Doberman pinschers with occult cardiomyopathy.
OBJECTIVE
To determine whether ventricular late potentials, detected by means of signal-averaged electrocardiography (SAECG), were associated with sudden death in Doberman Pinschers with occult cardiomyopathy.


METHODS
Case series.


METHODS
39 Doberman Pinschers with occult cardiomyopathy.


METHODS
Cardiomyopathy was diagnosed by means of serial echocardiography and ambulatory electrocardiography; SAECG was performed 1 or more times for each dog.


RESULTS
12 dogs died suddenly; the other 27 died after developing overt clinical signs of congestive heart failure. Results of SAECG were associated with outcome, and dogs in which ventricular late potentials were detected were more likely to die suddenly. however, 5 dogs for which results of SAECG were normal (n = 2) or equivocal (3) also died suddenly.


CONCLUSIONS
Results suggest that SAECG may be useful in predicting whether Doberman Pinschers with occult cardiomyopathy, confirmed on the basis of results of echocardiography, are at risk of dying suddenly. However, the possibility of sudden death cannot be ruled out simply because results of SAECG are normal.
Department of Small Animal Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602, USA.
C A
CA
Calvert
G J
GJ
Jacobs
M
M
Kraus
D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000627:therapeutic use; D009202:Cardiomyopathies / Q000401:mortality / Q000503:physiopathology / Q000662:veterinary*; D016757:Death, Sudden, Cardiac / Q000662:veterinary*; D004283:Dog Diseases / Q000188:drug therapy / Q000401:mortality / Q000503:physiopathology*; D004285:Dogs; D004562:Electrocardiography / Q000379:methods / Q000662:veterinary*; D015716:Electrocardiography, Ambulatory / Q000662:veterinary; D005260:Female; D008297:Male; D012815:Signal Processing, Computer-Assisted; D018487:Ventricular Dysfunction, Left / Q000401:mortality / Q000503:physiopathology / Q000662:veterinary*
D000889:Anti-Arrhythmia Agents