Nodular amyloidosis of the tongue.
Amyloidosis is a rare disease in otorhinolaryngology. It presents a wide range of clinical manifestations and its deposits can be found in various organs. In the paper, a case of a 73-year-old female patient with macroglossia, as a symptom of nodular amyloidosis is reported. The predominant features were dysphagia and speech impairment caused by the tongue protruding beyond the teeth. The histologic appearance consisted of a nodular pattern of amyloid deposition. The amyloid was of an AL (lambda-light chain) type as shown immunohistochemically. The presented case shows the importance of investigating the patient for co-existing disease.
Niemann
A M
AM
Dept. of Otorhinolaryngology, Head and Neck Surgery, University of Kiel, Germany.
Werner
J A
JA
D000368:Aged; D000686:Amyloidosis / Q000473:pathology*; D005260:Female; D006801:Humans; D008260:Macroglossia / Q000473:pathology; D008279:Magnetic Resonance Imaging; D014060:Tongue Diseases / Q000473:pathology*