Co-administration of cyclosporin enables oral therapy with paclitaxel.
Meerum Terwogt
J M
JM
Beijnen
J H
JH
ten Bokkel Huinink
W W
WW
Rosing
H
H
Schellens
J H
JH
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1 / Q000037:antagonists & inhibitors; D000284:Administration, Oral; D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000008:administration & dosage* / Q000493:pharmacokinetics; D001682:Biological Availability; D016572:Cyclosporine / Q000008:administration & dosage*; D004359:Drug Therapy, Combination; D006801:Humans; D007262:Infusions, Intravenous; D051379:Mice; D018345:Mice, Knockout; D009369:Neoplasms / Q000188:drug therapy; D017239:Paclitaxel / Q000008:administration & dosage* / Q000493:pharmacokinetics
D020168:ATP Binding Cassette Transporter, Subfamily B, Member 1; D000972:Antineoplastic Agents, Phytogenic; D016572:Cyclosporine; D017239:Paclitaxel