The functional anatomy of attention to visual motion. A functional MRI study.
Attention can enhance or modulate neural responses to stimuli at early and late stages of sensory processing. We were interested in the modulatory effect of attention to visual motion on cortical responses as measured by functional MRI. Subjects were scanned during repeated presentations of identical stimuli (visual motion) while only the attentional component of the task was varied. Enhanced haemodynamic responses during attentive conditions defined an occipitoparietofrontal system, including sensory and association areas, as well as the medial thalamus and superior colliculus. Attentional modulation was not restricted to extrastriate areas (including V3a and the V5 complex) but was also evident, to a lesser degree, in early visual areas close to the calcarine fissure (V1/V2 border). Attention-related enhancement of cortical responsiveness is discussed in terms of data that implicate modulatory short-term changes in synaptic efficacy and reciprocal connections between striate, extrastriate, parietal and frontal areas. Given the similarity of our attentional network to that controlling eye movements, the results of this study are in accord with theories linking oculomotor control and attention.
The Wellcome Department of Cognitive Neurology, Institute of Neurology, London, UK. cbuechel@fil.ion.ucl.ac.uk
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C
Büchel
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O
Josephs
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Rees
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Turner
C D
CD
Frith
K J
KJ
Friston
D001288:Attention / Q000502:physiology*; D001921:Brain / Q000033:anatomy & histology* / Q000502:physiology*; D001931:Brain Mapping; D005260:Female; D005625:Frontal Lobe / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009039:Motion Perception / Q000502:physiology*; D009778:Occipital Lobe / Q000502:physiology; D010296:Parietal Lobe / Q000502:physiology; D010775:Photic Stimulation / Q000379:methods; D011601:Psychophysics / Q000379:methods; D014796:Visual Perception / Q000502:physiology*