Cytometric DNA ploidy after different types of urinary diversions.
Patients undergoing uterosigmoidostomy (USS) have a high risk of developing colon cancer, while no evidence of an increased risk associated with rectal bladder (RB) has been reported. The purpose of the present study was to monitor the presence of aneuploidy by flow cytometry in patients who have undergone USS and RB as a possible basis for the identification of patients with an increased risk of malignant tumor occurrence. We have observed that 31% Of USS and 27% of RB cases were aneuploid. Data from the present investigation confirm that follow up studies may be useful in patients after urinary diversion.
Departments of Urology, Cristo Re Hospital, Rome, Italy.
M
M
Gallucci
P
P
Eleuteri
M G
MG
Grollino
D
D
Forte
R
R
De Vita
D000293:Adolescent; D000328:Adult; D000368:Aged; D000782:Aneuploidy; D003110:Colonic Neoplasms / Q000209:etiology; D005434:Flow Cytometry; D006801:Humans; D008875:Middle Aged; D012306:Risk; D014547:Urinary Diversion / Q000379:methods*