Contact dermatitis due to sodium colistimethate.
Colistin methanesulfonate sodium (CLMS) is a widely-used antibiotic. To our best knowledge, only two cases of contact allergy to CLMS have been reported. We described a 4-year-old girl with contact dermatitis evoked by CLMS that had been applied as an ophthalmic solution. The dermatitis started after administration for 21 days. The diagnosis was confirmed by as is and constituent patch tests. We reviewed the literature in which contact allergy due to CLMS and colistin sulfate is described.
Department of Dermatology, Yamagata University School of Medicine, Japan.
S
S
Sasaki
Y
Y
Mitsuhashi
S
S
Kondo
D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D002675:Child, Preschool; D003091:Colistin / Q000008:administration & dosage / Q000009:adverse effects / Q000031:analogs & derivatives*; D003877:Dermatitis, Contact / Q000209:etiology*; D003875:Drug Eruptions / Q000209:etiology*; D015817:Eye Infections / Q000517:prevention & control; D005137:Eye, Artificial; D005148:Facial Dermatoses / Q000175:diagnosis*; D005260:Female; D006801:Humans; D009883:Ophthalmic Solutions; D010328:Patch Tests
D000900:Anti-Bacterial Agents; D009883:Ophthalmic Solutions; C004691:colistinmethanesulfonic acid; D003091:Colistin