Unilateral retinoblastoma with acquired monosomy 7 and secondary acute myelomonocytic leukemia.
Patients with a nongenetic form of retinoblastoma are not particularly at high risk of developing second malignant neoplasms. We report here a case of treatment-related leukemia (secondary leukemia) with acquired monosomy 7, in a child with unilateral retinoblastoma.
Department of Pediatrics, Medical College of Ohio, Toledo 43699, USA.
E
E
Bayar
M G
MG
Robinson
T W
TW
Kurczynski
D001853:Bone Marrow / Q000473:pathology; D002675:Child, Preschool; D002897:Chromosomes, Human, Pair 7 / Q000235:genetics*; D005260:Female; D006801:Humans; D015479:Leukemia, Myelomonocytic, Acute / Q000175:diagnosis / Q000235:genetics* / Q000628:therapy; D009006:Monosomy / Q000175:diagnosis / Q000235:genetics*; D016609:Neoplasms, Second Primary / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D019572:Retinal Neoplasms / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D012175:Retinoblastoma / Q000235:genetics* / Q000473:pathology / Q000628:therapy