Synthesis of arylidenehydrazono- and glycopyranosylhydrazino-sulfonylbenzylidene-2,4-imidazolidinediones as potential antiviral and antitumoral agents.
A series of 5-[(Z)-(4-(2-(E)-arylidene)hydrazonosulfonylbenzylidene)]-2, 4-imidazolidinediones 6a-h and 5-[(Z)-(4-(2-beta-D-glycopyranosyl) hydrazinosulfonylbenzylidene)]-2,4-imidazolidinediones 10a-j were synthesized via two different routes. The compounds did not display any antiviral and antitumoral activity.
Chemistry Department, Faculty of Education, Tanta University (Kafr El-Sheikh Branch), Egypt. ahmed.khodair@mailexcite.com
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D000970:Antineoplastic Agents / Q000138:chemical synthesis*; D000998:Antiviral Agents / Q000138:chemical synthesis*; D001597:Benzylidene Compounds / Q000138:chemical synthesis; D006027:Glycosides / Q000737:chemistry; D006834:Hydrazines / Q000138:chemical synthesis; D007093:Imidazoles / Q000138:chemical synthesis*
D000970:Antineoplastic Agents; D000998:Antiviral Agents; D001597:Benzylidene Compounds; D006027:Glycosides; D006834:Hydrazines; D007093:Imidazoles