Suspected chromium picolinate-induced rhabdomyolysis.
Rhabdomyolysis results from skeletal muscle injury and release of muscle cell contents into plasma. A number of etiologic factors have been reported for the condition, including strenuous exercise, weight lifting, trauma, seizure, sepsis, and alcohol and drug abuse. Hundreds of drugs also reportedly cause rhabdomyolysis. A 24-year-old body builder developed the disease after ingesting 1200 microg of chromium picolinate (6-24 times the daily recommended allowance of 50-200 microg) over 48 hours. We believe this to be the first reported case of chromium-induced rhabdomyolysis.
Martin
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College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, USA.
Fuller
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D000328:Adult; D062787:Drug Overdose; D006801:Humans; D007502:Iron Chelating Agents / Q000008:administration & dosage / Q000009:adverse effects*; D010848:Picolinic Acids / Q000008:administration & dosage / Q000009:adverse effects*; D012206:Rhabdomyolysis / Q000139:chemically induced*
D007502:Iron Chelating Agents; D010848:Picolinic Acids; C030614:picolinic acid