Holt-Oram syndrome and multiple ventricular septal defects: an association suggesting a possible genetic marker?
A family is described where the father has the many skeletal, but none of the cardiac abnormalities associated with the Holt-Oram syndrome. His two daughters have similar skeletal anomalies, but with identical cardiac lesions, as does another patient, raising the possibility of an associated genetic marker.
Department of Cardiology, Royal Children's Hospital, Melbourne, Australia.
R G
RG
Bennhagen
S
S
Menahem
D000328:Adult; D001132:Arm / Q000002:abnormalities*; D005260:Female; D005819:Genetic Markers; D006345:Heart Septal Defects, Ventricular / Q000235:genetics*; D006801:Humans; D007223:Infant; D008297:Male; D013577:Syndrome
D005819:Genetic Markers