Natural killer cell lymphoma in cytology: breaking all the rules--a case report.
A testicular mass aspirate was received from a 22-yr-old patient with known non-Hodgkin's lymphoma. The cells were large and pleomorphic, occurring in syncytial fragments and demonstrating abundant cytoplasm. No lymphoglandular bodies were seen. As characteristic lymphoma criteria were not present, a cytodiagnosis of germ-cell tumor was suggested, and testicular biopsy advised. The final histopathology report, however, was of a CD 56-positive (large-cell) T-natural killer cell lymphoma, of which this appears to be the first example described and illustrated cytologically.
Department of Anatomical Pathology, School of Pathology, South African Institute for Medical Research, University of the Witwatersrand, Johannesburg, South Africa.
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Wright
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Cooper
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Leiman
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Davidge-Pitts
D000328:Adult; D001707:Biopsy, Needle; D019002:CD56 Antigen / Q000032:analysis; D003581:Cytodiagnosis; D003937:Diagnosis, Differential; D018237:Germinoma; D006801:Humans; D016130:Immunophenotyping; D007694:Killer Cells, Natural / Q000276:immunology / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis*; D016399:Lymphoma, T-Cell / Q000175:diagnosis*; D008297:Male; D012671:Seminiferous Tubules / Q000473:pathology; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000473:pathology; D013737:Testis / Q000473:pathology
D019002:CD56 Antigen