Laparoscopic gonadectomy in two patients with gonadal dysgenesis.
Individuals with androgen insensitivity syndrome have a high risk (20-30%) of developing malignancy in their gonads. Accordingly, bilateral gonadectomy is recommended. In a 17-year-old woman with Swyer syndrome gonads were located as streaks above the pelvic brim. In a 13-year-old with Morris syndrome they were located within the inguinal canals. Bilateral laparoscopic gonadectomy was performed under general anesthesia in both patients without complications. We suggest that in phenotypic females with 46,XY karyotype, the procedure may be performed safely, even with gonads located in inguinal canals.
Campo
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Department of Obstetrics and Gynecology, Catholic University of the Sacred Heart, Largo A. Gemelli 8, 00168 Rome, Italy.
Garcea
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N
D000293:Adolescent; D005260:Female; D006061:Gonadal Dysgenesis, 46,XY / Q000601:surgery*; D006066:Gonads / Q000601:surgery*; D006801:Humans; D007621:Karyotyping; D010535:Laparoscopy; D008297:Male; D010641:Phenotype