[Primary neuroendocrine carcinoma of the skin: clinical case].
A case of Merkel cell carcinoma of the skin is described. It is a rare primary skin tumor originating within the dermis with an aggressive biologic behavior. Clinical presentation of these tumors are not sufficiently distinctive to allow the preoperative diagnosis. Wide surgical excision with postoperative irradiation to the local site and regional lymphatics is recommended as the therapy of choice. Indications for chemotherapy are discussed and the guidelines for an appropriated follow-up are reported.
Tocchi
A
A
Istituto di I Clinica Chirurgica, Università degli Studi La Sapienza, Roma.
Maggiolini
F
F
Mazzoni
G
G
Liotta
G
G
Lepre
L
L
Costa
G
G
Miccini
M
M
D000368:Aged; D000369:Aged, 80 and over; D015266:Carcinoma, Merkel Cell / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D006801:Humans; D008297:Male; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery