The SSCP phenomenon: addition of HEPES buffer dramatically affects electrophoretic mobility.
City of Hope Nat'l Med Ctr/Beckman Research Inst., Department of Molecular Genetics, Duarte, CA 91010-3000, USA.
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Liu
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D002021:Buffers; D004247:DNA / Q000032:analysis* / Q000737:chemistry / Q000187:drug effects; D004586:Electrophoresis; D006531:HEPES / Q000737:chemistry / Q000494:pharmacology; D002836:Hemophilia B / Q000235:genetics; D006801:Humans; D017354:Point Mutation / Q000235:genetics; D018807:Polymorphism, Single-Stranded Conformational; D012680:Sensitivity and Specificity
D002021:Buffers; D004247:DNA; D006531:HEPES