Minor salivary gland hyalinisation and amyloidosis in low-grade lymphoma of MALT.
Two patients with low-grade lymphoma of mucosa-associated lymphoid tissue (MALT) arising in primary Sjögren's syndrome developed solitary nodules in their lips. Histologically both lesions showed enlargement and hyalinisation of single minor salivary glands with acinar atrophy, loss of most ducts and conversion into almost acellular sclerotic eosinophilic masses. In one case the lesion was shown to contain an amyloid component. No amyloid was detected in the second case but deposition of collagen and basement membrane and sclerotic neoplasm were excluded.
Department of Oral Medicine and Pathology, United Medical and Dental Schools, Guy's Hospital, London, UK.
E W
EW
Odell
T
T
Lombardi
P J
PJ
Shirlaw
C A
CA
White
D000682:Amyloid / Q000032:analysis; D000686:Amyloidosis / Q000150:complications / Q000473:pathology*; D001284:Atrophy; D001485:Basement Membrane / Q000473:pathology; D003094:Collagen / Q000032:analysis; D004802:Eosinophilia / Q000473:pathology; D005260:Female; D006801:Humans; D006818:Hyalin / Q000737:chemistry*; D008047:Lip Diseases / Q000150:complications / Q000473:pathology*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications*; D008875:Middle Aged; D018987:Salivary Ducts / Q000473:pathology; D012466:Salivary Gland Diseases / Q000150:complications / Q000473:pathology; D012470:Salivary Glands, Minor / Q000473:pathology*; D012598:Sclerosis; D012859:Sjogren's Syndrome / Q000150:complications
D000682:Amyloid; D003094:Collagen