Energetics of the adsorption of some drug onto the sclerotium of Pleurotus tuber-regium.
The thermodynamic parameters of the adsorption of iodine, acetyl-salicylic acid [aspirin] sodium salicylate and pyridoxine hydrochloride onto the powder of sclerotium of pleurotus tuber-regium has been studied. Negative delta G values were obtained for the adsorption of the drugs onto the powdered sclerotium. The negative delta G values show that adsorption is favoured in this spontaneous process, that is, the process led to a decrease in the free energy of the system. The free energy of segregation or surface enrichment factor caused by combination of the material was 46. delta H values calculated for the adsorption of the drugs onto the sclerotium were all negative as well as the delta S values. All these indicate that the adsorption was an exothermic process.
Department of Pharmaceutics Faculty of Pharmaceutical Sciences, University of Nigeria, Nsukka.
M U
MU
Adikwu
K C
KC
Ofokansi
D000327:Adsorption; D000363:Agaricales / Q000737:chemistry*; D004735:Energy Transfer; D004364:Pharmaceutical Preparations / Q000737:chemistry*
D004364:Pharmaceutical Preparations