Bernard-Soulier syndrome in pregnancy: case report and review of the literature.
Bernard-Soulier Syndrome is a rare hereditary thrombocytopathy that manifests clinically by excessive bleeding out of proportion to the degree of thrombocytopenia. Only eight reports of Bernard-Soulier Syndrome in pregnancy have been previously described. In some patients the pregnancy course was smooth while in others post-partum haemorrhage was the most common complication. We present a primiparous female who had immediate and delayed post-partum haemorrhage that was managed conservatively. Review of the literature is also included.
Khalil
A
A
Department of Obstetrics and Gynaecology, American University of Beirut Medical Center, Lebanon.
Seoud
M
M
Tannous
R
R
Usta
I
I
Shamseddine
A
A
D000328:Adult; D001606:Bernard-Soulier Syndrome / Q000150:complications* / Q000235:genetics; D003241:Consanguinity; D000077324:Crystalloid Solutions; D015237:Dinoprost / Q000031:analogs & derivatives / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007552:Isotonic Solutions; D010121:Oxytocin / Q000627:therapeutic use; D010952:Plasma Substitutes / Q000627:therapeutic use; D006473:Postpartum Hemorrhage / Q000188:drug therapy / Q000209:etiology*; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic
D000077324:Crystalloid Solutions; D007552:Isotonic Solutions; D010952:Plasma Substitutes; D010121:Oxytocin; C030319:prostaglandin F2alpha 15-methyl ether; D015237:Dinoprost