TRP, TRPL and trouble in photoreceptor cells.
Calcium influx through the TRP and TRPL light-activated channels triggers a complex regulatory hierarchy resulting in positive and negative feedback regulation of the phototransduction cascade. Recent studies have begun to elucidate the function of TRP and TRPL in vivo, and to examine their relationship to intracellular calcium changes during the light response.
Howard Hughes Medical Institute, University of California at San Diego, La Jolla 92093-0649, USA. kristin@flyeye.ucsd.edu
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Scott
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Zuker
D000818:Animals; D015220:Calcium Channels / Q000502:physiology*; D002148:Calmodulin-Binding Proteins / Q000502:physiology*; D004330:Drosophila / Q000502:physiology*; D029721:Drosophila Proteins; D008565:Membrane Proteins / Q000502:physiology*; D017956:Photoreceptor Cells, Invertebrate / Q000737:chemistry / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*; D050052:TRPC Cation Channels; D050051:Transient Receptor Potential Channels
D015220:Calcium Channels; D002148:Calmodulin-Binding Proteins; D029721:Drosophila Proteins; D008565:Membrane Proteins; D050052:TRPC Cation Channels; D050051:Transient Receptor Potential Channels; C096351:transient receptor potential cation channel, subfamily C, member 1; C074192:trpl protein, Drosophila