Mitochondrial oversight of cellular Ca2+ signaling.
Mitochondria, the metabolic powerhouses of the cell, can sequester and release large amounts of Ca2+. This import and export of Ca2+ helps to adjust energy production to cellular needs. Recent advances show that mitochondrial Ca2+ fluxes play a major role in normal Ca2+ signaling.
Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle 98195-7290, USA. donner@u.washington.edu
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D002118:Calcium / Q000502:physiology*; D015220:Calcium Channels / Q000502:physiology*; D008564:Membrane Potentials / Q000502:physiology; D008928:Mitochondria / Q000737:chemistry / Q000502:physiology*; D015398:Signal Transduction / Q000502:physiology*
D015220:Calcium Channels; D002118:Calcium