Kimura's disease of the lacrimal gland.
A 33-year-old Japanese woman had bilateral eyelid swelling and soft tumor of the right orbit. Increased serum IgE and eosinophilia in the peripheral blood was observed. Magnetic resonance imaging of the lesion showed hypointense orbital fat on T1-weighted image and isointense orbital fat on T2-weighted image. Gd-DTPA T1-weighted images demonstrated marked enhancement. The histopathological appearance of the tumor was consistent with Kimura's disease. On a regimen of 60 mg of prednisone per day, the orbital mass reduced in size. A review of the recent literature indicated that corticosteroids rather than surgery might be tried at least initially as treatment.
Department of Ophthalmology, Shimane Medical University, Izumo, Japan.
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Kodama
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Kawamoto
D000328:Adult; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism; D015415:Biomarkers / Q000032:analysis; D004802:Eosinophilia / Q000175:diagnosis; D005141:Eyelid Diseases / Q000175:diagnosis; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007124:Immunoenzyme Techniques; D007766:Lacrimal Apparatus Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000378:metabolism; D008279:Magnetic Resonance Imaging; D009916:Orbital Diseases / Q000175:diagnosis; D011241:Prednisone / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
D015415:Biomarkers; D005938:Glucocorticoids; D011241:Prednisone