Holt-Oram syndrome and multiple ventricular septal defects: an association suggesting a possible genetic marker?
A family is described where the father has the many skeletal, but none of the cardiac abnormalities associated with the Holt-Oram syndrome. His two daughters have similar skeletal anomalies, but with identical cardiac lesions, as does another patient, raising the possibility of an associated genetic marker.
Bennhagen
R G
RG
Department of Cardiology, Royal Children's Hospital, Melbourne, Australia.
Menahem
S
S
D000328:Adult; D001132:Arm / Q000002:abnormalities*; D005260:Female; D005819:Genetic Markers; D006345:Heart Septal Defects, Ventricular / Q000235:genetics*; D006801:Humans; D007223:Infant; D008297:Male; D013577:Syndrome
D005819:Genetic Markers