Intrapericardial interferon in the management of malignant pericardial effusion.
A patient with pericardial tamponade secondary to malignant pericardial effusion underwent pericardiocentesis followed by intrapericardial instillation of recombinant interferon alfa-2b (INTRON A; Schering-Plough; Kenilworth, NJ). The patient subsequently received a full course of chemotherapy and radiation therapy for her primary malignant tumor and experienced no recurrence of the pericardial effusion.
Wilkins
H E
HE
Department of Surgery, Columbus-Cabrini Medical Center, Chicago, USA.
Cacioppo
J
J
Connolly
M M
MM
Marquez
G
G
Grays
P
P
D000230:Adenocarcinoma / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002305:Cardiac Tamponade / Q000209:etiology / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007267:Injections; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000008:administration & dosage / Q000627:therapeutic use*; D008175:Lung Neoplasms / Q000150:complications* / Q000188:drug therapy / Q000532:radiotherapy; D008875:Middle Aged; D019152:Paracentesis; D010490:Pericardial Effusion / Q000209:etiology / Q000628:therapy*; D010496:Pericardium; D011994:Recombinant Proteins
D000970:Antineoplastic Agents; D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins