Two neuronal retinal components of the electroretinogram c-wave.
Although the rising phase of the b-wave seems to be generated mainly in the rod bipolar cells and the cone on-bipolar cells, the slow component of the electroretinogram, the c-wave, evidently originates in the Müller cells and the pigment epithelium. The c-wave has three components. One cornea-positive component derives from the pigment epithelium, while a distal cornea-negative component (slow PIII) and a proximal slow component originate in the Müller cells. This third proximal component of the c-wave differs between mammalian species: it is negative in the rat retina, positive in the rabbit and human retina and may be lacking in the cat retina.
Carl-Ludwig-Institute of Physiology, University of Leipzig, Germany.
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Hanitzsch
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Lichtenberger
D000818:Animals; D002415:Cats; D004596:Electroretinography; D006801:Humans; D066298:In Vitro Techniques; D007395:Interneurons / Q000502:physiology*; D008564:Membrane Potentials; D009457:Neuroglia / Q000502:physiology*; D010857:Pigment Epithelium of Eye / Q000502:physiology; D011817:Rabbits; D051381:Rats; D012160:Retina / Q000502:physiology*; D017949:Retinal Cone Photoreceptor Cells / Q000502:physiology