[The combined action of ionizing radiation and nitro compounds on the activity of the basic enzymes of glutamic acid metabolism].
The activity of aspartate aminotransferase, glutamate dehydrogenase in the liver of rats in 1, 7 and 15 days after gamma irradiation effect of the dose of 0.5 Gy on the background of consumption by animals of sodium nitrate, sodium nitrite and nitrosodiethylamine was studied. The combined influence of chemical agents and gamma irradiation modified the effects of nitro compounds-xenobiotics on processes of the synthesis and dissociation of the glutamic acid as well as the intensity of transamination of the reamination by aspartate aminotransferase.
Byelorussian State University, Minsk.
T N
TN
Zyrianova
V M
VM
Lavrova
D000586:Amination / Q000187:drug effects / Q000528:radiation effects; D000704:Analysis of Variance; D000818:Animals; D001219:Aspartate Aminotransferases / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects*; D003641:Deamination / Q000187:drug effects / Q000528:radiation effects; D005720:Gamma Rays; D005969:Glutamate Dehydrogenase / Q000187:drug effects* / Q000378:metabolism / Q000528:radiation effects*; D018698:Glutamic Acid / Q000378:metabolism* / Q000528:radiation effects*; D008099:Liver / Q000187:drug effects / Q000201:enzymology / Q000528:radiation effects; D008297:Male; D009574:Nitro Compounds / Q000494:pharmacology*; D051381:Rats; D013997:Time Factors
D009574:Nitro Compounds; D018698:Glutamic Acid; D005969:Glutamate Dehydrogenase; D001219:Aspartate Aminotransferases