[The effect of weak electromagnetic fields and ionizing radiation on the regeneration of the murine sciatic nerve].
The influence of X-ray impulses (dose 0.003 cGy, longitudity 10 ns) and EM impulses (induction 0.003 mT) on sciatic nerve regeneration in mice after crush lesion was studied. Limb jerk amplitude at electric stimulation of nerve and postural reflex in thin rod in X + EM and EM groups were restored within 13th days after lesion, in control group within 15 days (p < 0.05). The beginning of repairing of postural reflex was early in X + EM group than on EM group, rehabilitation of limb jerk amplitude--in EM group. Histological examination demonstrated that myelin degenerated in EM group more rapidly as compared with X + EM and control groups. This data suppose different effects of EM and X + EM impulses on nerve-regenerating processes.
Dudkin
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AO
Petersburg Nuclear Physics Institute, Department of Radiation and Molecular Biophysics, Russian Academy of Science. dudkin@OMRB.PNPT.SPB.RU
Zamuraev
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IN
D000818:Animals; D004307:Dose-Response Relationship, Radiation; D004558:Electric Stimulation; D004574:Electromagnetic Fields; D006614:Hindlimb; D007537:Isometric Contraction; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D008808:Mice, Inbred CBA; D009416:Nerve Regeneration / Q000528:radiation effects*; D012584:Sciatic Nerve / Q000502:physiology* / Q000528:radiation effects*; D013997:Time Factors