Catalytic antibodies.
Following the end of the first decade in catalytic antibody research, recent efforts are reflecting a more introspective view of the field. Notably, X-ray crystal structure analyses of antibody catalysts are permitting an increased understanding of the evolution and modus operandi of these remarkable biocatalysts. Additionally, the breadth and scope of new antibody-catalyzed reactions and novel hapten design strategies have continued to flourish with support from an increasing number of contributors to this ever expanding area.
Wentworth
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Department of Chemistry (BCC582), The Scripps Research Institute, The Skaggs Institute for Chemical Biology, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. paulw@scripps.edu
Janda
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D000906:Antibodies / Q000737:chemistry*; D001709:Biotechnology; D002384:Catalysis; D006801:Humans
D000906:Antibodies