Molecular characterization of a TEM-21 beta-lactamase in a clinical isolate of Morganella morganii.
A clinical isolate of Morganella morganii, with reduced susceptibility to expanded-spectrum cephalosporins and aztreonam, was found to produce an extended-spectrum beta-lactamase with a pI of 6.4. The nucleotide sequence of the encoding gene was that of the gene encoding TEM-21. This is the first molecular characterization of an extended-spectrum beta-lactamase in M. morganii.
Tessier
F
F
Laboratoire de Microbiologie, Université de Bordeaux 2, Bordeaux, France. Tessier@bacterio.u-bordeaux2.fr
Arpin
C
C
Allery
A
A
Quentin
C
C
D001483:Base Sequence; D006801:Humans; D008826:Microbial Sensitivity Tests; D008969:Molecular Sequence Data; D011511:Proteus / Q000187:drug effects / Q000201:enzymology*; D001618:beta-Lactamases / Q000235:genetics*
D001618:beta-Lactamases