[PGE2 and induction of labor. Authors' experience].
BACKGROUND
The aim of this work is to contribute to the evaluation of the dinoprostone clinical value (PGE2) in labor induction. Special attention is paid to the evaluation of the effectiveness and safety of the method employed, as well as to the singling out of possible predictive factors of success.


METHODS
The study was carried out on a sample of 85 women, who underwent labor induction by intracervical application of a gel containing 0.5 mg of dinoprostone. The following parameters were evaluated: 1) percentage of spontaneous deliveries within 24 hours from the administration of dinoprostone; 2) kind of delivery (comparison with women who delivered without labor induction); 3) characteristics of the cardiotocogram performed soon after the application of the gel; 4) prognostic value of some factors (maternal age, parity, gestational age, Bishop score).


RESULTS
The difference between the two categories compared according to susceptibility of a positive answer to the treatment with PGE2 is mainly the consequence of different Bishop scores. The Bishop score was the only examined having an autonomous prognostic value and a real indicator of success prospects of an attempt to induce, labor by administration of PG.


CONCLUSIONS
In personal experience, the una tantum intracervical application of dinoprostone is an effective method and, at the same time, it is free from any major risk.
Scuola Autonoma di Ostetricia, Università degli Studi di Roma La Sapienza.
S R
SR
Indraccolo
F
F
Rech
S
S
Lojodice
A
A
Patella
D000328:Adult; D015232:Dinoprostone / Q000008:administration & dosage* / Q000494:pharmacology; D005260:Female; D006801:Humans; D007751:Labor, Induced / Q000379:methods*; D011247:Pregnancy
D015232:Dinoprostone