Systemic Fusarium oxysporum infection in an immunocompetent patient with an adult respiratory distress syndrome (ARDS) and extracorporal membrane oxygenation (ECMO).
We report a case of disseminated fusariosis in a 42-year-old patient with adult respiratory distress syndrome (ARDS) and extracorporal membrane oxygenation (ECMO), but without definite immunosuppression. Fusarium oxysporum was isolated from a bronchial lavage taken 6 days ante mortem. Despite antifungal treatment with amphotericin B and flucytosine the patient died in septic multiorgan failure. A post-mortem examination was performed. The patient's liver was found to contain fungus cells and F. oxysporum could be cultured from ascites.
Abteilung Mikrobiologie und Hygiene, Institut für Medizinische Mikrobiologie und Hygiene, Freiburg, Germany.
A
A
Sander
U
U
Beyer
R
R
Amberg
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D015199:Extracorporeal Membrane Oxygenation; D005670:Fusarium; D006801:Humans; D007121:Immunocompetence; D008107:Liver Diseases / Q000382:microbiology; D008172:Lung Diseases, Fungal / Q000382:microbiology; D008297:Male; D009181:Mycoses / Q000150:complications* / Q000188:drug therapy / Q000401:mortality; D012128:Respiratory Distress Syndrome / Q000150:complications* / Q000401:mortality
D000935:Antifungal Agents; D000666:Amphotericin B