[Detection of HIV antibodies in pooled sera].
The use of sera mixtures for the detection of HIV antibodies was studied in a population of low prevalence (0.006%), using the diagnosis systems of national production: Recombinant HIV UMELISA and RECHIV 1 + 2. The systems were evaluated with individual samples and mixtures of 5 and 10 sera from healthy blood donors and from HIV-1 and/or HIV-2 positive and undetermined persons. It was observed that the utilization of mixtures of 10 sera is not feasible; however, the use of mixtures of 5 affects neither the specificity nor the sensitivity of the systems studied.
Centro de Investigaciones Científicas de la Defensa Civil.
G
G
López
C
C
Silva
J
J
Benítez
D015492:AIDS Serodiagnosis / Q000191:economics / Q000379:methods*; D001782:Blood Donors; D003906:Developing Countries; D004797:Enzyme-Linked Immunosorbent Assay; D005240:Feasibility Studies; D015483:HIV Antibodies / Q000097:blood*; D015528:HIV Seroprevalence; D015497:HIV-1 / Q000276:immunology*; D015498:HIV-2 / Q000276:immunology; D006801:Humans; D012680:Sensitivity and Specificity
D015483:HIV Antibodies