[Recurrence after treatment of breast intraductal carcinoma].
OBJECTIVE
To assess the risk of local recurrence of intraductal carcinoma of the breast with a large series and a review of literature.


METHODS
We present a retrospective study of 331 cases treated for intraductal carcinoma of the breast. Only patients with at least 5 years follow-up were selected. We were specially interested in recurrence risk factors. In these patients with a long follow-up; pathology was reevaluated with new investigation technique.


RESULTS
After a median follow-up of 109 months, 40 local recurrences were observed; these lesions were invasive in 23 cases. Only one patient had recurrence after mastectomy. For the others, they had lumpectomy associated with radiotherapy in 12 cases. Histologic features, grade and therapeutic options were evaluated as risk factors of local recurrence.


CONCLUSIONS
Follow-up after lumpectomy for intraductal carcinoma was studied. The status of tumor margins was important; irradiation appeared useful, specially in case of high grade carcinoma but further large prospective randomized studies are needed. The use of prognostic index is interesting, but there are still unanswered questions.
Institut Bergonié, Bordeaux.
O
O
Jourdain
C
C
Tunon de Lara
N
N
Quenel
E
E
Stöckle
E
E
Bussières
A
A
Faucher
V
V
Acharian
C
C
Vilbas-Guegan
I
I
de Mascarel
M
M
Trojani
J M
JM
Dilhuydy
A
A
Avril
D001943:Breast Neoplasms / Q000473:pathology* / Q000628:therapy*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000473:pathology* / Q000628:therapy*; D005260:Female; D006801:Humans; D008408:Mastectomy; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000628:therapy*; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D017211:Treatment Failure