Focal ischemic injury of middle cerebral artery in newborn infants.
Three full term newborns with focal ischemic injury of the middle cerebral artery (MCA) were observed. Diagnosis was suspected by cerebral ultrasonography (US) in the first year of life and then was confirmed by CT-scan and/or MRI. All children had a history of pre-perinatal risk factors of fetal impairment. Neuropsychological outcome, ranging from normal to severe, was evaluated in all three patients; it appears to be related to the type and extension of cerebral injury. In full-term neonates with discrete, moderate or severe neurologic symptoms the possibility of focal ischemic injury in the MCA territory should be considered.
Department of Neonatology, University of Chieti, Italy.
S
S
Domizio
A
A
Verrotti
F
F
Chiarelli
G
G
Sabatino
D002536:Cerebral Arteries / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D002546:Ischemic Attack, Transient / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D008297:Male; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography