Thrombomodulin levels in Behçet's disease with and without the factor V Leiden mutation.
The plasma levels of thrombomodulin (TM) in 34 patients with Behçet's disease and 79 healthy control subjects were studied. Eight patients had the factor V Leiden (FVL) mutation. The TM level was significantly lower in patients with the FVL mutation than in patients without the mutation and in the healthy controls (p < 0.05 and p < 0.01). However, there was no difference in overall mean plasma TM concentration between the patients without the mutation and the healthy controls.
Gürgey
A
A
Department of Pediatric Hematology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Gurler
A
A
Oner
A F
AF
Mesci
L
L
Kirazli
S
S
D001528:Behcet Syndrome / Q000097:blood* / Q000235:genetics*; D016009:Chi-Square Distribution; D004797:Enzyme-Linked Immunosorbent Assay; D005165:Factor V / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D009154:Mutation / Q000235:genetics*; D012016:Reference Values; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric; D018180:Thrombomodulin / Q000097:blood* / Q000235:genetics
D018180:Thrombomodulin; C095381:factor V Leiden; D005165:Factor V