[Incidence of CIN in HIV-positive women].
BACKGROUND
The aim of this study was to evaluate the incidence of CIN in HIV-seropositive women.


METHODS
A group of 23 women with a mean age of 28 years was recluted. Three of them were clinically affected, and 20 were non-AIDS HIV-seropositive. The patients underwent cervical cytology, colposcopically directed biopsy and T-cell studies. In addition, HPV using the in vitro hybridization, was investigated.


RESULTS
Eight of 23 patients (24.78%) had CIN. Patients with CIN had significantly lower CD4 cell counts and CD4/CD8 ratios than those without CIN. Patients with AIDS had higher grade lesions than those non-AIDS HIV-sero-positive.


CONCLUSIONS
The data obtained suggest that abnormal cervical pathology is common among HIV seropositive women, and so cervical colposcopy should be part of the routine management of HIV-seropositive women.
Zarcone
R
R
II Università degli Studi-Napoli.
Bellini
P
P
Carfora
E
E
Longo
M
M
Monarca
M
M
Tomasillo
G
G
Lizza
R
R
D000328:Adult; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006679:HIV Seropositivity / Q000175:diagnosis*; D006801:Humans; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000821:virology; D002578:Uterine Cervical Dysplasia / Q000150:complications*