[Indocyanine green angiography in "multiple evanescent white dot syndrome" (MEWDS)].
OBJECTIVE
Multiple evanescent white dot syndrome (MEWDS) is a benign acquired chorioretinal disorder occurring mostly in young adults. Its pathophysiology is unknown. To describe the results of indocyanine green angiography (ICGA) in MEWDS.


METHODS
Four patients with MEWDS were investigated by ICGA.


RESULTS
In all cases, ICGA revealed numerous choroidal hypofluorescent lesions that largely outnumbered the lesions visible with either fundoscopy or fluorescein angiography. Three cases showed a blind spot enlargement on perimetry associated with the presence of a large peripapillary hypofluorescent zone on ICGA. Three cases showed macular granularity on fundoscopy correlating with a significant subfoveal hypfluorescent lesion on ICGA. Evolution was always favorable with disappearance of the hypofluorescent choroidal lesions.


CONCLUSIONS
Our results confirm that MEWDS is primarily a choroidal disorder. The blind spot enlargement and the macular granularity, frequently detected in MEWDS, result from larger peripapillary and subfoveal choroidal lesions.
Hôpital Ophtalmique Jules Gonin, Lausanne.
A B
AB
Desarnaulds
F X
FX
Borruat
C P
CP
Herbort
C
C
de Courten
D000328:Adult; D015862:Choroid Diseases / Q000175:diagnosis*; D003287:Contrast Media; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D012164:Retinal Diseases / Q000175:diagnosis*; D013577:Syndrome; D014794:Visual Fields / Q000502:physiology
D003287:Contrast Media; D007208:Indocyanine Green