Activation of opioid receptors inhibits neuronal-like calcium channels, distal steps of secretion, and cell proliferation in human small cell lung carcinoma cells.
Codignola
A
A
CNR Cellular and Molecular Pharmacology Center, Milan, Italy.
Missale
C
C
Spano
P
P
Clementi
F
F
Carbone
E
E
Sher
E
E
D019900:3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer / Q000494:pharmacology; D000700:Analgesics / Q000494:pharmacology*; D003994:Bucladesine / Q000494:pharmacology; D015220:Calcium Channels / Q000187:drug effects / Q000502:physiology*; D018288:Carcinoma, Small Cell; D002455:Cell Division / Q000187:drug effects; D000242:Cyclic AMP / Q000378:metabolism; D020875:Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; D020881:Enkephalin, D-Penicillamine (2,5)-; D004745:Enkephalins / Q000494:pharmacology; D006801:Humans; D007700:Kinetics; D008175:Lung Neoplasms; D009270:Naloxone / Q000494:pharmacology; D009474:Neurons / Q000502:physiology*; D017465:Receptors, Opioid, delta / Q000187:drug effects / Q000502:physiology*; D012701:Serotonin / Q000494:pharmacology*; D019284:Thapsigargin / Q000494:pharmacology; D013997:Time Factors; D014407:Tumor Cells, Cultured
D000700:Analgesics; D015220:Calcium Channels; D004745:Enkephalins; D017465:Receptors, Opioid, delta; D020875:Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; D012701:Serotonin; D009270:Naloxone; D003994:Bucladesine; D019900:3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; D019284:Thapsigargin; D020881:Enkephalin, D-Penicillamine (2,5)-; D000242:Cyclic AMP