[Three adults with mild varicella and bronchial mucosal lesions].
We encountered three adults with varicella and bronchial mucosal lesions. Respiratory symptoms were minimal in all three. Chest X-ray films showed bilateral, diffuse, small, nodular shadows. Small, elevated lesions with white plaque's were seen on the bronchial mucosa bronchoscopically. Transbronchial lung biopsy, bronchial mucosal biopsy, and bronchoalveolar lavage were also done. The lung-biopsy specimen showed infiltration of lymphocytes into the interstitial space: VZV antigen was found by immunohistochemical staining of the lesion in one case. Analysis of bronchoalveolar lavage fluid revealed abnormally low CD 4/8 ratios in three cases. These findings suggest a high incidence of respiratory complications, especially bronchial lesions, despite the lack of respiratory symptoms, in adults with varicella.
Department of Internal Medicine, Konan Hospital, Toyohira-ku Sapporo, Hokkaido, Japan.
S
S
Konno
Y
Y
Tsuneta
E
E
Jinushi
H
H
Ukita
T
T
Harada
A
A
Aida
Y
Y
Nishiura
W
W
Takahashi
T
T
Kawai
D000328:Adult; D001980:Bronchi / Q000473:pathology* / Q000821:virology; D001995:Bronchography; D002644:Chickenpox / Q000000981:diagnostic imaging / Q000473:pathology* / Q000821:virology; D005260:Female; D014645:Herpesvirus 3, Human / Q000302:isolation & purification; D006801:Humans; D008297:Male; D009092:Mucous Membrane / Q000473:pathology / Q000821:virology; D011024:Pneumonia, Viral / Q000000981:diagnostic imaging / Q000473:pathology* / Q000821:virology