Cycle-specific replication of chromosomal and F-plasmid origins.
There have been various proposals for the pattern of F-plasmid replication during the division cycle. Here we show that the recent studies of Gordon et al. (Cell 90, 1113-1121, 1997) on the duplication and segregation of green fluorescent protein (GFP) labeled replication origins of the Escherichia coli chromosome and the F plasmid during the division cycle support the proposal that the F plasmid replicates with a cell-cycle-specific (artiocyclic) pattern.
Cooper
S
S
Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor 48109-0620, USA. cooper@umich.edu
Keasling
J D
JD
D002453:Cell Cycle / Q000502:physiology; D004261:DNA Replication; D004926:Escherichia coli / Q000235:genetics / Q000502:physiology*; D005144:F Factor / Q000502:physiology*; D049452:Green Fluorescent Proteins; D008164:Luminescent Proteins; D018741:Replication Origin
D008164:Luminescent Proteins; D049452:Green Fluorescent Proteins