[Spontaneous rupture of the spleen in a patient treated with chemotherapy and growth factors for stem cell mobilization].
The Authors report a case of spontaneous spleen rupture in a woman with breast cancer treated with chemotherapy and growth factors for stem cell mobilization. After a wide review of the literature, they suppose this therapy, causing a considerable increase of immature cells, that promote the stasis of the splenic microcirculation, can sometime elicit a spontaneous rupture of the organ.
Clinica Chirurgica Generale, Università degli Studi di Messina.
M
M
Rossitto
A
A
Versaci
A
A
Barbera
M
M
Broccio
V
V
Lepore
A
A
Ciccolo
D000328:Adult; D001943:Breast Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D019650:Hematopoietic Stem Cell Mobilization; D006801:Humans; D012422:Rupture, Spontaneous; D013154:Spleen / Q000187:drug effects / Q000293:injuries*