Antiacetylcholine receptor Fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant specificities in serum and block the action of pathogenic serum antibodies.
Department of Immunology, Scripps Research Institute, La Jolla, California 92037, USA.
Y F
YF
Graus
M H
MH
de Baets
D R
DR
Burton
D000918:Antibody Specificity; D001323:Autoantibodies / Q000097:blood*; D001435:Bacteriophages; D002478:Cells, Cultured; D006801:Humans; D007140:Immunoglobulin Fab Fragments / Q000276:immunology* / Q000302:isolation & purification; D009157:Myasthenia Gravis / Q000276:immunology*; D019151:Peptide Library; D011950:Receptors, Cholinergic / Q000276:immunology*; D013601:T-Lymphocytes / Q000276:immunology*; D013950:Thymus Gland / Q000276:immunology
D001323:Autoantibodies; D007140:Immunoglobulin Fab Fragments; D019151:Peptide Library; D011950:Receptors, Cholinergic