Four new sesquiterpenes from Petasites formosanus.
Four new eremophilane-type sesquiterpenes, petasones A (1) and B (2), S-petasitin (3), and petasinol (4), were isolated from the aerial parts of Petasites formosanus. Their structures were elucidated by spectroscopic and chemical methods as 3alpha-[(Z)-3-methylsulfinylacryloxy]eremophila-7(11), 9-dien-8-one; 3alpha-[(E)-3-methylsulfinylacryloxy]eremophila-7(11), 9-dien-8-one; 3alpha-[(Z)-3-methylthioacryloxy]-11-hydroxyeremophila -6, 9-dien-8-one; and 3alpha-[(E)-3-methylsulfinylacryloxy]-8beta-hydroxy eremophila-9, 11-diene, respectively.
National Research Institute of Chinese Medicine, Taipei 112, Taiwan, and Department of Chemistry, National Taiwan University, Taipei 106, Taiwan. yllin@cma23.nricm.edu.tw
Y L
YL
Lin
C H
CH
Mei
S L
SL
Huang
Y H
YH
Kuo
D002240:Carbohydrate Sequence; D002851:Chromatography, High Pressure Liquid; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008969:Molecular Sequence Data; D010084:Oxidation-Reduction; D010946:Plants, Medicinal / Q000737:chemistry*; D012717:Sesquiterpenes / Q000032:analysis*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013624:Taiwan
D012717:Sesquiterpenes