Combinatorial chemistry using polymer-supported reagents.
During the past several years, the field of combinatorial chemistry has expanded to include not only solid- and solution-phase methods for expedited compound synthesis, but also hybrid approaches that span these two extremes. In particular, polymer-supported reagents have emerged as useful combinatorial chemistry tools for the discovery and optimization of new pharmaceutical leads.
Kaldor
S W
SW
Lilly Research Laboratories, Lilly Corporate Center, Eli Lilly and Company Indianapolis, IN 46285, USA. Kaldor@lilly.com
Siegel
M G
MG
D002625:Chemistry, Organic; D007202:Indicators and Reagents / Q000737:chemistry*; D055601:Organic Chemistry Phenomena; D011108:Polymers / Q000737:chemistry*
D007202:Indicators and Reagents; D011108:Polymers