A cytotoxic pennogenin glycoside from Majanthemum dilatatum.
A cytotoxic pennogenin glycoside, pennogenin 3-O-alpha-L-rhamnopyranosyl-(1-->4)-alpha-L-rhamnopyranosyl-(1-->4)-[ alpha-L-rhamnopyranosyl-(1-->2)]-beta-D-glucopyranoside (1) was isolated from the whole herb of Majanthemum dilatatum. Compound 1 showed potent cytotoxic activity against human cancer cell lines.
E R
ER
Woo
J M
JM
Kim
H J
HJ
Kim
S H
SH
Yoon
H
H
Park
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002240:Carbohydrate Sequence; D006801:Humans; D008969:Molecular Sequence Data; D010944:Plants / Q000737:chemistry; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D014407:Tumor Cells, Cultured
D000972:Antineoplastic Agents, Phytogenic; D012503:Saponins; C113878:pennogenin 3-O-rhamnopyranosyl-1-4-rhamnopyranosyl-1-4-(rhamnopyranosyl-1-2)-glucopyranoside