Amyloid tumours in the soft tissues of the legs. Case report and review of the literature.
We present a case of multiple amyloidomas occurring in the calves of a 61-year-old woman, without systemic amyloidosis or plasma cell dyscrasia. The disappearance of Congo red positivity after potassium permanganate treatment and immunohistochemical results showed that this was a case of reactive AA amyloidosis. True soft tissue amyloidomas are extremely rare, and this is the first case of AA amyloidoma in the soft tissues of the legs.
Institute of Pathologic Anatomy and Histology, University of Perugia, Italy.
A
A
Sidoni
P F
PF
Alberti
S
S
Bravi
E
E
Bucciarelli
D000682:Amyloid / Q000032:analysis; D000686:Amyloidosis / Q000000981:diagnostic imaging / Q000473:pathology*; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007866:Leg; D008875:Middle Aged; D011859:Radiography; D012983:Soft Tissue Neoplasms / Q000737:chemistry / Q000000981:diagnostic imaging / Q000473:pathology*
D000682:Amyloid; D014408:Biomarkers, Tumor