Has psoriasis its own characteristic trichogram?
The aim of this study was to determine if there were characteristic trichogram changes in scalp psoriasis in patients without clinically evident effluvium or alopecia. A total of 45 patients (17 men and 28 women, aged from 15 to 73 years) with clinically and histologically confirmed psoriasis vulgaris with scalp involvement were included. The control group consisted of 60 volunteers (23 males and 37 females aged from 15 to 74 years) with no scalp involvement. Our results from the psoriatic group showed highly increased proportions of dysplastic hair roots. Median proportion was 50% with 95% confidence interval (CI) for median 30-60%, whereas telogen hair ratio was slightly increased-median proportion was 16% with 95% CI for median 15-20%. Within the psoriasis patients' group no statistically significant correlations were found between the proportion of dysplastic hairs and the patients' age, sex, and the intensity and duration of disease. According to the results of this study, the dysplastic hairs in scalp psoriasis are statistically significant much more frequently compared with the control group. Thus, the increased proportion of dysplastic hairs in scalp psoriasis without effluvium or alopecia might be its characteristic trichogram sign.
Deutsches Medizinisches Zentrum, Ein Bokek, Dead Sea, Israel.
A
A
Stanimirović
M
M
Skerlev
T
T
Stipić
T
T
Beck
A
A
Basta-Juzbasić
D
D
Ivanković
D000293:Adolescent; D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007633:Keratins / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000378:metabolism*; D012536:Scalp Dermatoses / Q000378:metabolism*
D007633:Keratins