Detection of designer drugs in human hair by ion mobility spectrometry (IMS).
Since its inception in the early 1970s under the name plasma chromatography, ion mobility spectrometry (IMS) has undergone great changes. It is now utilized more and more in forensic science laboratories where it is used to detect explosives and environmental pollutants [1-4] as well as its use in detecting drugs of abuse [5-8]. Although IMS is known for nearly 30 years now [9], relatively few cases of the application of ion mobility spectrometry to the analysis of human hair have been reported [10-12]. The authors report a new and quick method to rapidly screen and determine MDMA ('ecstasy', 'Adam') and MDEA ('Eve') in human hair. The proposed method using trihexylamine as internal standard resulted in a rapid procedure useful in screening human hair specimens for designer drugs.
Institute of Forensic Medicine, University of Salzburg, Austria.
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T
Keller
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A
Miki
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Regenscheit
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Dirnhofer
A
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Schneider
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Tsuchihashi
D015104:3,4-Methylenedioxyamphetamine / Q000031:analogs & derivatives / Q000032:analysis; D015198:Designer Drugs / Q000032:analysis*; D005554:Forensic Medicine; D006197:Hair / Q000737:chemistry*; D006213:Hallucinogens / Q000032:analysis; D006801:Humans; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000032:analysis; D012680:Sensitivity and Specificity; D018629:Spectrometry, Mass, Secondary Ion / Q000379:methods*; D019966:Substance-Related Disorders / Q000378:metabolism
D015198:Designer Drugs; D006213:Hallucinogens; D015104:3,4-Methylenedioxyamphetamine; D018817:N-Methyl-3,4-methylenedioxyamphetamine; C051800:3,4-methylenedioxyethamphetamine