A canine model of acute hydrocephalus with MR correlation.
Within 3 hours of induction of acute hydrocephalus in a canine model, lateral ventricular CSF pressure increased from an initial average of 14.6 +/- 2.8 cm H2O to 40.2 +/- 5.7 cm H2O. Ventricular volumes, as measured from MR images, increased 1.45 +/- 0.94 cm3, 1.92 +/- 0.82 cm3, and 2.24 +/- 0.60 cm3 after 6, 24, and 48 hours, of hydrocephalus, respectively. This canine model was reliable and consistent with clinical conditions.
Department of Radiology, The New York Hospital, Cornell University Medical College, New York 10021, USA.
T
T
Vullo
R
R
Manzo
D G
DG
Gomez
M D
MD
Deck
P T
PT
Cahill
D000208:Acute Disease; D000818:Animals; D002552:Cerebral Ventricles / Q000473:pathology; D015170:Cerebrospinal Fluid Pressure / Q000502:physiology; D004195:Disease Models, Animal; D004285:Dogs; D006849:Hydrocephalus / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D012826:Silicone Elastomers
D012826:Silicone Elastomers