[The course and outcome of drug addiction based on long-term catamnesis].
The paper reports 20-year follow-up results (from 1976-1977 to 1996-1997) of 175 patients with drug addiction that began at the young age. The patients with opiate addiction prevailed. Structural-dynamic alterations of the main clinic symptom complexes, the validity of the factors that are essential for the reduction of pathological drive are analyzed. There was a tendency to progressive decrease of narcotics administration as the severity of somatic pathology increased. Episodes of narcotics administration were permanent by the end of the second decade of the disease in less than 20% of the patients from the primary cohort; alcohol and psychotropic drug (hypnotics, tranquilizers) dependence has developed in about 1/3 of the patients. The most influence on the regress of pathologic drive had the factors related with both the duration of the isolation from narcotics and the development of schizophrenic process; therapeutic regress was observed much rarer. High lethality of the patients with drug addiction was found: more than 46% during 20 years of the disease.
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Chirko
D000293:Adolescent; D000328:Adult; D000437:Alcoholism / Q000628:therapy; D002648:Child; D005500:Follow-Up Studies; D006556:Heroin Dependence / Q000628:therapy; D006801:Humans; D008297:Male; D002189:Marijuana Abuse / Q000628:therapy; D009293:Opioid-Related Disorders / Q000628:therapy; D017063:Outcome Assessment, Health Care; D019966:Substance-Related Disorders / Q000401:mortality / Q000628:therapy*; D013997:Time Factors