Polymerase chain reaction and other molecular techniques used in the diagnosis of tuberculosis.
The new techniques of molecular biology using nucleic acid probes and genic amplification as the ligase chain reaction and the polymerase chain reaction, are routinely used for the detection and rapid identification of M. tuberculosis. The higher costs of these methods as compared to the conventional biochemical test is compensated for because rapid identification allows early implementation of prevention measures.
Istituto di Microbiologia, Università Cattolica del S. Cuore, Policlinico A. Gemelli, Roma, Italy.
G
G
Fadda
M
M
Sanguinetti
D015342:DNA Probes; D005784:Gene Amplification; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D014376:Tuberculosis / Q000175:diagnosis*
D015342:DNA Probes