Improved myocardial ischemia detection by combined physical and mental stress testing.
The hypothesis that addition of mental stress to physical exercise would modify the circulation response to stress and improve noninvasive detection of myocardial ischemia was tested in a randomized, crossover radionuclide angiocardiographic study. Compared with physical exercise or mental stress alone, combined stress led to higher heart rates and rate-pressure products in early stress stages, to more pronounced symptoms, and to a better discrimination of subjects with and without coronary artery disease by radionuclide angiography.
Division of Cardiology, University Hospital, Basel, Switzerland.
P R
PR
Hunziker
C
C
Gradel
J
J
Müller-Brand
P
P
Buser
M
M
Pfisterer
D000328:Adult; D000368:Aged; D018592:Cross-Over Studies; D003937:Diagnosis, Differential; D005080:Exercise Test / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000000981:diagnostic imaging* / Q000209:etiology / Q000523:psychology*; D011877:Radionuclide Imaging; D013315:Stress, Psychological / Q000150:complications*