Cutaneous Rosai-Dorfman disease.
We report a patient with purely cutaneous Rosai-Dorfman disease (RDD) who presented with a solitary, asymptomatic plaque on the back of her left thigh, with characteristic, large histiocytoid cells exhibiting emperipolesis histologically. Cutaneous lesions occur in 27% of patients with lymph node involvement in RDD however purely cutaneous disease has only been reported on 18 previous occasions. The aetiology is unknown, although it is though to be a reactive disorder rather than neoplastic, possibly an immunological response to an infectious agent.
Child
F J
FJ
Department of Dermatology, King's College Hospital, London, U.K.
Fuller
L C
LC
Salisbury
J
J
Higgins
E M
EM
D000328:Adult; D005260:Female; D015618:Histiocytosis, Sinus / Q000473:pathology*; D006801:Humans; D012871:Skin Diseases / Q000473:pathology*; D013848:Thigh