Magnesium silicate treatment of dietary heated fats: effects on rat liver enzyme activity.
In an effort to reduce the deleterious nutritional effects of oxidation products generated in heated fats, a partially hydrogenated soybean oil (PHSBO) used 7 d (7-DH) for frying foodstuffs was obtained from a commercial deep-fat frying operation. The used fat was treated with magnesium silicate (T-7DH). Isocaloric diets containing 15% of either 7-DH or T-7-DH fats were prepared and fed to male weanling rats for 10 wk in a pair-feeding experiment and compared to control rats fed nonheated PHSBO (NH). Animals fed the 7-DH diet showed higher liver enzyme cytochrome b5 and P450 activity than the T-7DH diet compared to the NH group, suggesting a positive effect of the treatment. These results suggested the presence of lower amounts of harmful compounds in the diet containing the heated used oil which had been treated with the active adsorbent.
Department of Food Science and Human Nutrition, University of Illinois at Urbana-Champaign, Urbana 61801, USA. eperkins@uiuc.edu
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D000818:Animals; D002334:Carnitine O-Palmitoyltransferase / Q000378:metabolism; D004041:Dietary Fats / Q000378:metabolism / Q000494:pharmacology*; D005954:Glucosephosphate Dehydrogenase / Q000378:metabolism; D006865:Hydrogenation; D007521:Isocitrate Dehydrogenase / Q000378:metabolism; D017633:Magnesium Silicates; D008297:Male; D008862:Microsomes, Liver / Q000187:drug effects / Q000201:enzymology*; D009251:NADPH-Ferrihemoprotein Reductase / Q000378:metabolism; D051381:Rats; D017207:Rats, Sprague-Dawley; D013024:Soybean Oil / Q000494:pharmacology
D004041:Dietary Fats; D017633:Magnesium Silicates; C005013:Florisil; D013024:Soybean Oil; D007521:Isocitrate Dehydrogenase; D005954:Glucosephosphate Dehydrogenase; D009251:NADPH-Ferrihemoprotein Reductase; D002334:Carnitine O-Palmitoyltransferase