Synthesis and biological activities of some 4,5-dihydro-1H-1,2,4-triazol-5-one derivatives.
Nine new 1,3,4-trisubstituted-4,5-dihydro-1H-1,2,4-triazol-5-ones were synthesized and characterized by elemental analysis, 1H NMR, IR and UV spectra. These new and 30 recently reported 3,4-disubstituted- and 1,3,4-trisubstituted-4,5-dihydro-1H-1,3,4-triazol-5-ones were screened for antibacterial, antitumor and anti-HIV activities.
Ikizler
A A
AA
Department of Chemistry, Karadeniz Technical University, Trabzon, Turkey.
Demirbas
A
A
Johansson
C B
CB
Celik
C
C
Serdar
M
M
Yuksek
H
H
D007659:Ketones / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D013329:Structure-Activity Relationship; D014230:Triazoles / Q000138:chemical synthesis* / Q000494:pharmacology
D007659:Ketones; D014230:Triazoles