Bladder involvement in systemic sclerosis: urodynamic and histological evaluation in 23 patients.
Lower tract involvement of systemic sclerosis is an uncommon manifestation. In this study we have evaluated the functional and morphologic vesical changes in 23 female patients with systemic sclerosis to investigate if bladder dysfunction was correlated with an extended skin sclerosis and/or a more serious organ involvement. Urodynamic alterations were observed in only 3 cases. Urinary symptoms and urodynamic features were correlated neither with severity of vesical fibrosis nor with visceral involvement. Autonomic dysfunction was detected in 13 patients.
Department of Urology, University of Pisa, Italy. rminervi@dc.med.unipi.it
R
R
Minervini
G
G
Morelli
A
A
Minervini
S
S
Pampaloni
A
A
Tognetti
L
L
Fiorentini
M L
ML
Ciompi
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001341:Autonomic Nervous System / Q000503:physiopathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D012595:Scleroderma, Systemic / Q000150:complications* / Q000473:pathology; D012867:Skin / Q000473:pathology; D001743:Urinary Bladder / Q000473:pathology; D001745:Urinary Bladder Diseases / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000503:physiopathology; D014563:Urodynamics