Natural killer cell lymphoma in cytology: breaking all the rules--a case report.
A testicular mass aspirate was received from a 22-yr-old patient with known non-Hodgkin's lymphoma. The cells were large and pleomorphic, occurring in syncytial fragments and demonstrating abundant cytoplasm. No lymphoglandular bodies were seen. As characteristic lymphoma criteria were not present, a cytodiagnosis of germ-cell tumor was suggested, and testicular biopsy advised. The final histopathology report, however, was of a CD 56-positive (large-cell) T-natural killer cell lymphoma, of which this appears to be the first example described and illustrated cytologically.
Wright
C A
CA
Department of Anatomical Pathology, School of Pathology, South African Institute for Medical Research, University of the Witwatersrand, Johannesburg, South Africa.
Cooper
K
K
Leiman
G
G
Davidge-Pitts
M
M
D000328:Adult; D001707:Biopsy, Needle; D019002:CD56 Antigen / Q000032:analysis; D003581:Cytodiagnosis; D003937:Diagnosis, Differential; D018237:Germinoma; D006801:Humans; D016130:Immunophenotyping; D007694:Killer Cells, Natural / Q000276:immunology / Q000473:pathology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis*; D016399:Lymphoma, T-Cell / Q000175:diagnosis*; D008297:Male; D012671:Seminiferous Tubules / Q000473:pathology; D013736:Testicular Neoplasms / Q000175:diagnosis* / Q000473:pathology; D013737:Testis / Q000473:pathology
D019002:CD56 Antigen