Triterpenes and saponins from Rudgea viburnioides.
A novel triterpene, viburgenin (1), has been isolated from an extract of the ripe fruit rinds of Rudgea viburnioides, together with the known saponins, arjunglucoside I and trachelosperosides B-1 and E-1, and the triterpenes trachelosperogenin B (2) and arjungenin. Compound 2 was previously obtained as a product from enzymatic hydrolysis, and it is reported for the first time as a natural product. The structure of compound 1 was determined as 2alpha,3beta, 19alpha,23,24-pentahydroxyurs-12-ene by extensive use of 1D and 2D NMR spectroscopic methods. Compound 1 exhibited moderate antifungal activity against Cladosporium cladosporioides.
Young
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MC
Seção de Fisiologia e Bioquímica de Plantas, Instituto de Botânica, CP. 4005, 01061-970, São Paulo, SP, Brazil.
Araújo
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AR
da Silva
C A
CA
Lopes
M N
MN
Trevisan
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LM
Bolzani
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VS
D000935:Antifungal Agents / Q000302:isolation & purification* / Q000494:pharmacology; D001938:Brazil; D002855:Chromatography, Thin Layer; D002963:Cladosporium / Q000187:drug effects; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D008826:Microbial Sensitivity Tests; D010946:Plants, Medicinal / Q000737:chemistry*; D012503:Saponins / Q000302:isolation & purification* / Q000494:pharmacology; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D014315:Triterpenes / Q000302:isolation & purification* / Q000494:pharmacology
D000935:Antifungal Agents; D012503:Saponins; D014315:Triterpenes; C113739:viburgenin