[Rhino-orbito-cerebral mucormycosis: clinical presentation].
BACKGROUND
Rhino-orbito-cerebral mucormycosis is an opportunistic rapidly progressive infection affecting almost exclusively diabetic or immunocompromised patients.


METHODS
Three cases are reported. For one patient mucormycosis was the first manifestation of juvenile diabetes and the evolution was favorable. In the second case the infection affected a known diabetic patient and the clinical course was fatal. The third patient was immunocompromised, showed mild clinical features and a rapidly fatal evolution, the diagnosis being made only postmortem.


CONCLUSIONS
These three cases illustrate the wide clinical spectrum of rhino-orbito-cerebral mucormycosis, its serious nature and difficult diagnosis.
Hôpital Ophtalmique Jules Gonin, Lausanne. fborruat@hola.hospvd.ch
J S
JS
Borruat
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Borruat
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Ducrey
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S
Uffer
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Pasche
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Maire
D000293:Adolescent; D003922:Diabetes Mellitus, Type 1 / Q000175:diagnosis / Q000473:pathology; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis / Q000473:pathology; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D016921:Meningitis, Fungal / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D009091:Mucormycosis / Q000175:diagnosis* / Q000473:pathology; D009668:Nose Diseases / Q000175:diagnosis* / Q000473:pathology; D009894:Opportunistic Infections / Q000175:diagnosis* / Q000473:pathology; D009916:Orbital Diseases / Q000175:diagnosis* / Q000473:pathology; D010254:Paranasal Sinus Diseases / Q000175:diagnosis* / Q000473:pathology; D010256:Paranasal Sinuses / Q000473:pathology