GM1 does not affect PDGF-BB-stimulated [3H] thymidine incorporation or neuritogenesis in SH-SY5Y cells treated with phosphorothioate oligonucleotides antisense to PDGF-A.
Department of Pathology, Ohio State University College of Medicine, Columbus 43210, USA.
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Hynds
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Kniss
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Yates
D000077214:Becaplermin; D005677:G(M1) Ganglioside / Q000494:pharmacology*; D006801:Humans; D016501:Neurites / Q000187:drug effects* / Q000502:physiology; D009447:Neuroblastoma; D016376:Oligonucleotides, Antisense / Q000494:pharmacology*; D010982:Platelet-Derived Growth Factor / Q000235:genetics* / Q000494:pharmacology*; D020574:Proto-Oncogene Proteins c-sis; D011994:Recombinant Proteins / Q000494:pharmacology; D013873:Thionucleotides; D013936:Thymidine / Q000378:metabolism; D014407:Tumor Cells, Cultured
D016376:Oligonucleotides, Antisense; D010982:Platelet-Derived Growth Factor; D020574:Proto-Oncogene Proteins c-sis; D011994:Recombinant Proteins; D013873:Thionucleotides; D000077214:Becaplermin; D005677:G(M1) Ganglioside; D013936:Thymidine