[The anti-inflammatory action of the mineral bischofite].
The anti-inflammatory effect of local application of a solution of the mineral bischofite was demonstrated in experiments with edema of the rat foot caused by phlogogenic agents serotonin, histamine, carragheenin, and formaldehyde. Per os administration of the solution increased the survival of mice with burns of the skin on the hind part of the body and reduced 1.74-fold the time of healing of a burn ulcer of the oral mucosa in a rabbit. The mineral bischofite stimulates phagocytizing activity of neutrophils and produces a bacteriostatic effect.
Spasov
A A
AA
Department of Pharmacology, Volgograd Medical Academy, Russia.
Ostrovskiĭ
O V
OV
Smirnova
L A
LA
Gerchikov
L V
LV
Temkin
E S
ES
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology / Q000627:therapeutic use*; D002056:Burns / Q000188:drug therapy; D002351:Carrageenan; D004338:Drug Combinations; D004353:Drug Evaluation, Preclinical; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D005557:Formaldehyde; D006632:Histamine; D015636:Magnesium Chloride / Q000494:pharmacology / Q000627:therapeutic use*; D051379:Mice; D008826:Microbial Sensitivity Tests; D008903:Minerals; D011817:Rabbits; D051381:Rats; D012701:Serotonin; D013997:Time Factors
D000894:Anti-Inflammatory Agents, Non-Steroidal; D004338:Drug Combinations; D008903:Minerals; C072517:bishofit; D015636:Magnesium Chloride; D005557:Formaldehyde; D012701:Serotonin; D006632:Histamine; D002351:Carrageenan