[Use of doxazosin (Cardura-Pfizer), alpha 1-adrenoreceptor antagonist, in treatment of hypertension in patients with diabetes].
Doxazosin (Cardura-Pfizer) is a alpha 1-adrenoreceptor antagonist. This drug significantly decreases the blood pressure in subjects with hypertension. Despite decreasing blood pressure, doxazosin has a beneficial effect on many disorders observed in subjects with diabetes mellitus. Doxazosin 1) improves the regulation of lipids disturbances, 2) improves tissue sensitivity to insulin, 3) decreases the frequency of sexual disorders. In this situation Doxazosin is a good choice in the treatment of hypertension in diabetic subjects, in subjects with hypertension and hypercholesterolemia, with left ventricular hypertrophy, in old male subjects with hypertension and benign prostatic hypertrophy.
Katedry i Kliniki Chorób Wewnetrznych i Diabetologii, Slaskiej Akademii Medycznej w Katowicach.
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Grzeszczak
D000317:Adrenergic alpha-Antagonists / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D000818:Animals; D003925:Diabetic Angiopathies / Q000150:complications / Q000188:drug therapy*; D017292:Doxazosin / Q000627:therapeutic use*; D006801:Humans; D006937:Hypercholesterolemia / Q000150:complications; D006973:Hypertension / Q000150:complications / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011470:Prostatic Hyperplasia / Q000150:complications
D000317:Adrenergic alpha-Antagonists; D017292:Doxazosin