Gene therapy for melanoma in humans.
As melanoma evolves, it interacts with the immune system. Based on this immunobiology, there are now a number of rationally designed attempts to develop genetically modified melanoma vaccines. This article outlines immunologic and other strategies in gene therapy for melanoma and provides an overview of current clinical trials.
Division of Hematology/Oncology, University of Pennsylvania School of Medicine, Philadelphia, USA.
R
R
Gutzmer
D
D
Guerry
D015316:Genetic Therapy / Q000379:methods*; D006801:Humans; D008545:Melanoma / Q000235:genetics / Q000276:immunology / Q000628:therapy*; D012878:Skin Neoplasms / Q000235:genetics / Q000276:immunology / Q000628:therapy*