A trial to investigate the relationship between DFO pharmacokinetics and metabolism and DFO-related toxicity.
Porter
J B
JB
Department of Haematology, University College London, England. j.porter@ucl.ac.uk
Faherty
A
A
Stallibrass
L
L
Brookman
L
L
Hassan
I
I
Howes
C
C
D000293:Adolescent; D000328:Adult; D001299:Audiometry; D003676:Deferoxamine / Q000009:adverse effects* / Q000493:pharmacokinetics*; D004596:Electroretinography / Q000187:drug effects; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000139:chemically induced; D006801:Humans; D007502:Iron Chelating Agents / Q000009:adverse effects* / Q000493:pharmacokinetics*; D008297:Male; D008657:Metabolic Clearance Rate; D017086:beta-Thalassemia / Q000188:drug therapy*
D007502:Iron Chelating Agents; D003676:Deferoxamine