Inhibition of amyloid formation: a strategy to delay the onset of Alzheimer's disease.
Converging evidence suggests that the formation of amyloid plaques may play a central role in the pathogenesis of Alzheimer's disease and that blocking amyloid formation may be an effective therapeutic strategy.
Lansbury
P T
PT
Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA 02115, USA. lansbury@cnd.bwh.harvard.edu
D000544:Alzheimer Disease / Q000188:drug therapy* / Q000378:metabolism; D016229:Amyloid beta-Peptides / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006801:Humans; D058225:Plaque, Amyloid / Q000187:drug effects* / Q000378:metabolism
D016229:Amyloid beta-Peptides