Magnetic resonance imaging in a case of Wernicke's encephalopathy.
Wernicke's encephalopathy is an uncommon disorder caused by a thiamine deficiency which is clinically characterized by the triad of ophthalmoplegia, ataxia and disturbances of consciousness, each finding being variably present. The disease is caused by malnutrition or malabsorption, and is often associated with prolonged alcohol intake, neoplasm and extensive inflammatory processes of the digestive tract and parenteral hyperalimentation-induced gastrointestinal mucosal atrophy. Clinical diagnosis can be elusive and MRI may be the only imaging technique able to detect the cerebral lesions, whose type and distribution are characteristic of the Wernicke's encephalopathy, whereas CT is positive only in exceptional cases. We report a case of a 56-year-old woman who developed a Wernicke's encephalopathy 1 month after a colonic resection with signal intensity changes located in the mammillary bodies and in the medial thalamic nuclei.
Institute of Radiology, University of Trieste, Cattinara Hospital, Strada di Fiume, I-34 149 Trieste, Italy.
L
L
Pagnan
G
G
Berlot
R S
RS
Pozzi-Mucelli
D001921:Brain / Q000473:pathology; D003082:Colectomy; D003110:Colonic Neoplasms / Q000150:complications / Q000601:surgery; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011182:Postoperative Care; D014899:Wernicke Encephalopathy / Q000150:complications / Q000175:diagnosis*