Spiral CT angiography of the renal arteries: should a scan delay based on a test bolus injection or a fixed scan delay be used to obtain maximum enhancement of the vessels?
OBJECTIVE
The purpose of this work was to assess the optimal scan delay for spiral CT angiography (SCTA) of the renal arteries in achieving optimal vascular contrast enhancement and to compare the utility of a delay based on these bolus injection versus that of a fixed scan delay.


METHODS
Seventy patients underwent renal artery SCTA with a 140 ml bolus of contrast agent injected a 3 ml/s. In 35 patients (Group A), a fixed scan delay of 27 s was used; in the other 35 (Group B), the scan delay was based on the transit time (TTest) of a test bolus injection. The scan delays in this group were set at TTest + 5 s (n = 5), TTest + 10 s (n = 8), TTest + 15 s (n = 4), or TTest + 20 s (n = 18). For all 70 patients, the time intervals between TRA (time to scanning the renal arteries) and TMax (time to maximum aortic enhancement after 140 ml bolus injection) were calculated, after which it was determined in which group of patients TRA occurred closest to TMax. Linear regression and mean squared error (MSE) were used for statistical analysis.


RESULTS
For Group A, mean TRA and TMax were 38 and 50 s, respectively. Mean (TRA - TMax) was -12 s with MSE of 185.76. For Group B, mean TRA and Tmax were 45 and 52 s. Mean (TRA - TMax) values were -15, -12, -11, and -1 s for scan delays of TTEST + 5 s, TTEST + 10 s, TTest + 15 s, and TTEST + 20 s, respectively, with MSEs of 253.80, 158.00, 137.50, and 30.00.


CONCLUSIONS
SCTA of the renal arteries was best performed with a scan delay of TTEST + 20 s. However, analysis of our data showed that similar results could be expected with a delay of 44 s.
Department of Radiology, University Hospital Utrech, The Netherlands.
R
R
Kaatee
M S
MS
Van Leeuwen
E E
EE
De Lange
J E
JE
Wilting
F J
FJ
Beek
J J
JJ
Beutler
W P
WP
Mali
D000293:Adolescent; D000328:Adult; D000368:Aged; D003287:Contrast Media / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D011856:Radiographic Image Enhancement / Q000295:instrumentation / Q000379:methods*; D012077:Renal Artery / Q000000981:diagnostic imaging*; D013997:Time Factors; D015898:Tomography Scanners, X-Ray Computed / Q000706:statistics & numerical data; D014057:Tomography, X-Ray Computed / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data
D003287:Contrast Media