[The adjuvant and specific activity of transfer factors to Candida albicans antigens].
Activity of transfer-factor (TF) delayed type hypersensitivity in allogenic and xenogeneic have studied. Guinea pigs was been sensibilized Soluble antigens and whole cells Candida albicans for production TF. Both TF expressed non specific and specific activity in the guinea pig and mouse leucocytes inhibition migration in vitro and delayed type hypersensitivity in mica. Activity of TF to cellular antigen was lower then TF to soluble antigen in xenogeneic systems. However TF activity was some low for whole cells in xenogeneic systems.
Taras Shevchenko University, Kiev.
V A
VA
Borysov
Z V
ZV
Cheusova
O S
OS
Molozhava
D000276:Adjuvants, Immunologic / Q000032:analysis / Q000494:pharmacology*; D000818:Animals; D000946:Antigens, Fungal / Q000276:immunology*; D002176:Candida albicans / Q000276:immunology*; D002464:Cell Migration Inhibition; D004306:Dose-Response Relationship, Immunologic; D006168:Guinea Pigs; D006968:Hypersensitivity, Delayed / Q000276:immunology; D007111:Immunity, Cellular; D007114:Immunization / Q000379:methods; D051379:Mice; D014165:Transfer Factor / Q000032:analysis / Q000276:immunology*
D000276:Adjuvants, Immunologic; D000946:Antigens, Fungal; D014165:Transfer Factor