A role for alpha(187-199) in the conversion of agonist binding energy to the opening of the acetylcholine receptor ion channel.
Fairclough
R H
RH
Department of Neurology, University of California, Davis 95616, USA.
Gudipati
E
E
Lin
M Y
MY
Twaddle
G M
GM
Richman
D P
DP
Burkwall
D A
DA
Josephs
R
R
D000818:Animals; D000911:Antibodies, Monoclonal / Q000494:pharmacology*; D002217:Carbachol / Q000494:pharmacology; D018679:Cholinergic Agonists / Q000494:pharmacology; D000939:Epitopes / Q000737:chemistry / Q000276:immunology*; D015640:Ion Channel Gating / Q000187:drug effects / Q000502:physiology; D007473:Ion Channels / Q000276:immunology / Q000502:physiology*; D007700:Kinetics; D008958:Models, Molecular; D010446:Peptide Fragments / Q000737:chemistry / Q000276:immunology; D011950:Receptors, Cholinergic / Q000737:chemistry / Q000276:immunology / Q000502:physiology*
D000911:Antibodies, Monoclonal; D018679:Cholinergic Agonists; D000939:Epitopes; D007473:Ion Channels; D010446:Peptide Fragments; D011950:Receptors, Cholinergic; D002217:Carbachol