[17-ketosteroid sulfates and its application to kampo-medicine].
Traditional oriental medicine tells us that everything is interrelated and consists of combinations of opposing factors, "Yin-Yang". So we need to evaluate the normal state and pathologic condition from the perspective of dynamic hormone balance between cortisol and DHEA which are opposing and physiologically very important. Cortisol has a more functional side and is considered Yang, while DHEA has a more material side and is considered Yin. We tried to explain the concepts of KAMPO which include SHO (Yin-Yang. Excess-Deficiency), the 6 Stages of Disease and Deficiency of the Kidney, by measuring urinary 17-OHCS and 17-KS-S, metabolites of cortisol and DHEA. We think our effort may develop a good objective indicator of KAMPO's diagnosis and be useful for selecting of treatment.
Taketani
T
T
Department of Pediatrics, Kurobe City Hospital.
Furuya
E
E
Nishikaze
O
O
D015065:17-Hydroxycorticosteroids / Q000652:urine; D015068:17-Ketosteroids / Q000652:urine*; D000293:Adolescent; D002648:Child; D006801:Humans; D016709:Yin-Yang
D015065:17-Hydroxycorticosteroids; D015068:17-Ketosteroids