[Acetylcholinesterase-positive innervation in the regenerated thymus in old rats after surgical and chemical castration].
Surgical and chemical castrations in old rats result in the regeneration of the involuted thymus. The distribution of ACHE-positive nerves did not differ in the regenerated thymi after surgical and chemical castrations. A number of ACHE-positive nerves were detected not only in perivascular topography but also in the functioning thymus parenchyma. A marked difference in thymus density of ACHE-positive nerves was found in rats without castration. We assume that our findings represent an indirect evidence that cholinergic nerves stimulate lymphopoiesis in the thymus. (Fig. 6, Ref. 16.)
Ustav anatómie Lekárskej fakulty UPJS v Kosiciach, Slovakia.
F
F
Dorko
M
M
Kocisová
S
S
Rybárová
E
E
Dorko
D000110:Acetylcholinesterase / Q000032:analysis*; D000375:Aging; D000818:Animals; D007987:Gonadotropin-Releasing Hormone / Q000494:pharmacology; D008297:Male; D009412:Nerve Fibers / Q000737:chemistry*; D009919:Orchiectomy; D051381:Rats; D012038:Regeneration; D013737:Testis / Q000187:drug effects*; D013950:Thymus Gland / Q000294:innervation* / Q000502:physiology
D007987:Gonadotropin-Releasing Hormone; D000110:Acetylcholinesterase