Systemic Fusarium oxysporum infection in an immunocompetent patient with an adult respiratory distress syndrome (ARDS) and extracorporal membrane oxygenation (ECMO).
We report a case of disseminated fusariosis in a 42-year-old patient with adult respiratory distress syndrome (ARDS) and extracorporal membrane oxygenation (ECMO), but without definite immunosuppression. Fusarium oxysporum was isolated from a bronchial lavage taken 6 days ante mortem. Despite antifungal treatment with amphotericin B and flucytosine the patient died in septic multiorgan failure. A post-mortem examination was performed. The patient's liver was found to contain fungus cells and F. oxysporum could be cultured from ascites.
Sander
A
A
Abteilung Mikrobiologie und Hygiene, Institut für Medizinische Mikrobiologie und Hygiene, Freiburg, Germany.
Beyer
U
U
Amberg
R
R
D000328:Adult; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D015199:Extracorporeal Membrane Oxygenation; D005670:Fusarium; D006801:Humans; D007121:Immunocompetence; D008107:Liver Diseases / Q000382:microbiology; D008172:Lung Diseases, Fungal / Q000382:microbiology; D008297:Male; D009181:Mycoses / Q000150:complications* / Q000188:drug therapy / Q000401:mortality; D012128:Respiratory Distress Syndrome / Q000150:complications* / Q000401:mortality
D000935:Antifungal Agents; D000666:Amphotericin B