Catalytic antibodies.
Following the end of the first decade in catalytic antibody research, recent efforts are reflecting a more introspective view of the field. Notably, X-ray crystal structure analyses of antibody catalysts are permitting an increased understanding of the evolution and modus operandi of these remarkable biocatalysts. Additionally, the breadth and scope of new antibody-catalyzed reactions and novel hapten design strategies have continued to flourish with support from an increasing number of contributors to this ever expanding area.
Department of Chemistry (BCC582), The Scripps Research Institute, The Skaggs Institute for Chemical Biology, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA. paulw@scripps.edu
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D000906:Antibodies / Q000737:chemistry*; D001709:Biotechnology; D002384:Catalysis; D006801:Humans
D000906:Antibodies