Identifying proteins and post-translational modifications by mass spectrometry.
Major recent advances in hardware performance, sample-handling procedures and software algorithms now allow reliable and sensitive mass spectrometric identification of proteins. Mass spectrometry vastly outperforms traditional sequencing technologies and thereby greatly facilitates the elucidation of the functions of individual proteins as well as multiprotein complexes and larger protein assemblages.
Küster
B
B
Center for Experimental BioInformatics, Odense University, Denmark. kuster@cebi.ou.dk
Mann
M
M
D000595:Amino Acid Sequence; D000818:Animals; D013058:Mass Spectrometry / Q000379:methods; D010446:Peptide Fragments / Q000737:chemistry; D010449:Peptide Mapping; D011499:Protein Processing, Post-Translational; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism*
D010446:Peptide Fragments; D011506:Proteins