Cytokines and asthma.
Some of the main cytokines involved in the pathophysiology of bronchial asthma, their pathogenic role, and evidence concerning the importance of their action in asthma exacerbations and in perpetuating airway inflammation are reviewed. Therapeutic approaches using cytokines which counteract the inflammatory process of asthma are also examined.
Ferreira
M B
MB
Immunoallergology Unit, Hospital de Santa María School of Medicine, Lisbon, Portugal.
Carlos
A G
AG
D000818:Animals; D001249:Asthma / Q000276:immunology* / Q000503:physiopathology / Q000628:therapy; D018925:Chemokines / Q000276:immunology; D016207:Cytokines / Q000276:immunology* / Q000627:therapeutic use; D004804:Eosinophils / Q000737:chemistry / Q000502:physiology; D016178:Granulocyte-Macrophage Colony-Stimulating Factor / Q000276:immunology; D006801:Humans; D006969:Hypersensitivity, Immediate / Q000276:immunology / Q000503:physiopathology; D007073:Immunoglobulin E / Q000502:physiology; D007371:Interferon-gamma / Q000276:immunology / Q000627:therapeutic use; D007378:Interleukins / Q000276:immunology / Q000627:therapeutic use; D014409:Tumor Necrosis Factor-alpha / Q000276:immunology
D018925:Chemokines; D016207:Cytokines; D007378:Interleukins; D014409:Tumor Necrosis Factor-alpha; D007073:Immunoglobulin E; D007371:Interferon-gamma; D016178:Granulocyte-Macrophage Colony-Stimulating Factor