Ultrasound-guided fine-needle aspiration diagnosis of adenocarcinoma of esophagus with signet-ring cell features arising in Barrett's esophagus: a case report.
We report a rarely documented case of adenocarcinoma of esophagus with signet-ring cell features arising in a Barrett's esophagus. This was diagnosed by employing combined endosonography and fine-needle aspiration cytology. The patient had progressive dysphagia and a poorly circumscribed mass involving the distal esophagus and gastroesophageal junction. An incisional biopsy was performed which showed Barrett's esophagus with highly atypical glands suspicious for adenocarcinoma. Following that, an ultrasound-guided endoscopic fine-needle aspiration revealed a cellular specimen with multiple groups and singly dispersed atypical glandular cells with a predominance of signet-rings features. These findings represented an adenocarcinoma with signet-ring cell features arise in Barrett's esophagus.
Baloch
Z
Z
Department of Pathology, Hospital of the University of Pennsylvania, Philadelphia 19104, USA. baloch@mail.med.upenn.edu
Lyle
S
S
Hoda
R S
RS
Gupta
P K
PK
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000209:etiology* / Q000473:pathology; D000368:Aged; D001471:Barrett Esophagus / Q000150:complications*; D001707:Biopsy, Needle; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D014463:Ultrasonography