[Use of an antioxidant complex in the treatment of endotoxicosis in reconstructive surgery of lower limb arteries].
During a dynamic examination of 69 patients with obliterating atherosclerosis of the lower extremity vessels who were subjected to different reconstructive operations on the distal portion of the aorta and arteries the content of the dienic conjugate and malonic dialdehyde was studies both before the operation and during different stages of the latter, as well as at the postoperative period. It was found that the patients had higher content of these substances both before and after operations. A scheme is proposed for the complex antioxidant therapy which allows the degree of endotoxicosis resulting from the activation of lipid peroxidation to be decreased.
Gavrilenko
G A
GA
Demin
V V
VV
D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000627:therapeutic use*; D001162:Arteriosclerosis Obliterans / Q000601:surgery*; D004731:Endotoxins / Q000378:metabolism; D006801:Humans; D007866:Leg / Q000098:blood supply*; D015227:Lipid Peroxidation; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D011183:Postoperative Complications / Q000378:metabolism; D013997:Time Factors; D014810:Vitamin E / Q000627:therapeutic use
D000975:Antioxidants; D004731:Endotoxins; D014810:Vitamin E; D008315:Malondialdehyde