[The effect of hormone substitution therapy on body weight].
BACKGROUND
The influence of hormone replacement therapy on the body weight has been studied.


METHODS
For this purpose, a group of 205 women in spontaneous menopause, were selected at the Menopause Centre in Suzzara: they were given a continuative replacement therapy for a period of 12 months (estradiol 50/60 micrograms and medroxyprogesterone acetate, 5/10 micrograms twelve days a month).


RESULTS
After twelve months, 30% of the 200 patients who completed the study, showed a weight increase which was significant only in 20%, with no variation of the Body Mass Index.


CONCLUSIONS
From the data obtained, two remarks can be done: the HRT contributes in an insignificant way to the body weight and probably these results must also be ascribed to the choice of neutral progestinics which do not possess androgenical mineralcorticoid effects.
Menozzi
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Reparto di Ostetricia e Ginecologica, Azienda USSL 22-Suzzara (Mantova).
D015992:Body Mass Index; D001835:Body Weight / Q000187:drug effects*; D004305:Dose-Response Relationship, Drug; D004958:Estradiol / Q000008:administration & dosage / Q000494:pharmacology; D015914:Estrogen Replacement Therapy; D005260:Female; D006801:Humans; D017258:Medroxyprogesterone Acetate / Q000008:administration & dosage / Q000494:pharmacology; D008593:Menopause; D008875:Middle Aged; D017698:Postmenopause
D004958:Estradiol; D017258:Medroxyprogesterone Acetate