A unique, naturally occurring single-amino acid mutation in HIV type 1 V3 loop can discriminate between its cytopathicity and replication in vivo and in vitro.
Retroviral Genetics Laboratory, Center for Virus Research, WIHR, Westmead Hospital, Sydney University, NSW, Australia.
B
B
Wang
R
R
Jozwiak
Y C
YC
Ge
N K
NK
Saksena
D000595:Amino Acid Sequence; D003545:Cysteine; D018450:Disease Progression; D015699:HIV Envelope Protein gp120 / Q000737:chemistry*; D015658:HIV Infections / Q000821:virology; D015497:HIV-1 / Q000235:genetics / Q000472:pathogenicity / Q000502:physiology*; D006801:Humans; D008969:Molecular Sequence Data; D009154:Mutation; D010446:Peptide Fragments / Q000737:chemistry*; D014779:Virus Replication
D015699:HIV Envelope Protein gp120; C059762:HIV envelope protein gp120 (305-321); D010446:Peptide Fragments; D003545:Cysteine