[Spontaneous rupture of the spleen in a patient treated with chemotherapy and growth factors for stem cell mobilization].
The Authors report a case of spontaneous spleen rupture in a woman with breast cancer treated with chemotherapy and growth factors for stem cell mobilization. After a wide review of the literature, they suppose this therapy, causing a considerable increase of immature cells, that promote the stasis of the splenic microcirculation, can sometime elicit a spontaneous rupture of the organ.
Rossitto
M
M
Clinica Chirurgica Generale, Università degli Studi di Messina.
Versaci
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Barbera
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Broccio
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Lepore
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V
Ciccolo
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D000328:Adult; D001943:Breast Neoplasms / Q000188:drug therapy / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D019650:Hematopoietic Stem Cell Mobilization; D006801:Humans; D012422:Rupture, Spontaneous; D013154:Spleen / Q000187:drug effects / Q000293:injuries*