Epidemiology of cleft lip and palate in Thailand.
During the years 1989 to 1991, a survey for the epidemiology of cleft lip and palate was carried out in Thailand using detailed forms. One thousand ninety-six patients were recorded and 593 patients were operated during that period. All records were analyzed. Six hundred forty-seven patients (59%) lived in northeastern Thailand. Of the 593 operated patients, 26% had cleft lip only, 48% had cleft lip and palate, and 25% had cleft palate only. Men predominated all groups except for the cleft palate-only group. Twenty-six of 593 patients had associated congenital anomalies. Two hundred thirty-seven of 1,096 patients had a history of cleft lip and palate in their first- and second-degree relatives (21.62%). Five hundred seventy-eight of 1,096 mothers (52.74%) had a history of taking drugs. Analgesics were among the drugs taken most often.
Department of Surgery, Siriraj Hospital Faculty of Medicine, Mahidol University, Bangkok, Thailand.
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Chuangsuwanich
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Aojanepong
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Muangsombut
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Tongpiew
D000014:Abnormalities, Drug-Induced / Q000453:epidemiology / Q000601:surgery; D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D002971:Cleft Lip / Q000139:chemically induced / Q000453:epidemiology* / Q000601:surgery; D002972:Cleft Palate / Q000139:chemically induced / Q000453:epidemiology* / Q000601:surgery; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D008423:Maternal Age; D010331:Paternal Age; D013785:Thailand / Q000453:epidemiology