Anticomplementary activity of constituents from the heartwood of Caesalpinia sappan.
The anticomplementary activity of compounds isolated from the heartwood of Caesalpinia sappan L. (Leguminosae) was investigated. The sterol mixture (campesterol 11.2%, stigmasterol 18.9% and beta-sitosterol 69.9%) was most potent and brazilin, brazilein, and protosappanin E showed a new anticomplementary activity on the complement system in vitro.
S R
SR
Oh
D S
DS
Kim
I S
IS
Lee
K Y
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Jung
J J
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Lee
H K
HK
Lee
D000818:Animals; D003169:Complement Inactivator Proteins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D007887:Fabaceae / Q000737:chemistry*; D006801:Humans; D010936:Plant Extracts / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal; D012756:Sheep
D003169:Complement Inactivator Proteins; D010936:Plant Extracts