Vanadium haloperoxidases.
The nature of the oxidized halogen intermediate in vanadium bromoperoxidase has recently been shown to depend on the nature of the organic substrate. For example, in the presence of indoles, vanadium bromoperoxidase does not release a freely diffusible oxidized halogen intermediate (such as HOBr+/-BR2+/-Br3-). Regioselective investigations are, therefore, now feasible.
Butler
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Department of Chemistry, University of California Santa Barbara, CA 93106-9510, USA. Butler@chem.ucsb.edu
D001665:Binding Sites / Q000502:physiology; D017605:Bromine Compounds / Q000378:metabolism; D017606:Chlorine Compounds / Q000378:metabolism; D017613:Iodine Compounds / Q000378:metabolism; D007700:Kinetics; D008667:Metalloproteins / Q000737:chemistry*; D010544:Peroxidases / Q000737:chemistry*; D013379:Substrate Specificity; D014639:Vanadium / Q000737:chemistry*
D017605:Bromine Compounds; D017606:Chlorine Compounds; D017613:Iodine Compounds; D008667:Metalloproteins; D014639:Vanadium; D010544:Peroxidases