A canine model of acute hydrocephalus with MR correlation.
Within 3 hours of induction of acute hydrocephalus in a canine model, lateral ventricular CSF pressure increased from an initial average of 14.6 +/- 2.8 cm H2O to 40.2 +/- 5.7 cm H2O. Ventricular volumes, as measured from MR images, increased 1.45 +/- 0.94 cm3, 1.92 +/- 0.82 cm3, and 2.24 +/- 0.60 cm3 after 6, 24, and 48 hours, of hydrocephalus, respectively. This canine model was reliable and consistent with clinical conditions.
Vullo
T
T
Department of Radiology, The New York Hospital, Cornell University Medical College, New York 10021, USA.
Manzo
R
R
Gomez
D G
DG
Deck
M D
MD
Cahill
P T
PT
D000208:Acute Disease; D000818:Animals; D002552:Cerebral Ventricles / Q000473:pathology; D015170:Cerebrospinal Fluid Pressure / Q000502:physiology; D004195:Disease Models, Animal; D004285:Dogs; D006849:Hydrocephalus / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D012826:Silicone Elastomers
D012826:Silicone Elastomers