Development of a cavernous malformation of the brain.
We report the appearance of a cavernous malformation associated with a developmental venous anomaly in a young boy 3 years after radiation therapy for a posterior fossa medulloblastoma. The presence of a stenosis of the venous drainage of the anomaly led us to postulate that venous restrictive disease, induced by radiation therapy, resulted in increased venous pressure and caused the formation of the cavernous malformation.
Department of Radiology/Interventional Radiology, CHUV, University Hospital, Lausanne, Switzerland.
P
P
Maeder
F
F
Gudinchet
R
R
Meuli
N
N
de Tribolet
D000293:Adolescent; D015901:Angiography, Digital Subtraction; D001932:Brain Neoplasms / Q000175:diagnosis*; D002528:Cerebellar Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D002533:Cerebral Angiography; D002543:Cerebral Hemorrhage / Q000175:diagnosis; D002550:Cerebral Veins / Q000002:abnormalities / Q000528:radiation effects; D003131:Combined Modality Therapy; D016371:Cranial Irradiation; D006392:Hemangioma, Cavernous / Q000175:diagnosis*; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008297:Male; D008527:Medulloblastoma / Q000532:radiotherapy* / Q000601:surgery; D009381:Neoplasms, Radiation-Induced / Q000175:diagnosis*; D011832:Radiation Injuries / Q000175:diagnosis*; D018714:Radiotherapy, Adjuvant