Epstein-Barr virus-associated lymphoproliferative disorder after autologous bone marrow transplantation: report of two cases.
Epstein-Barr virus-associated lymphoproliferative disorders have been frequently reported as a complication of solid organ and allogeneic bone marrow transplantation. Their occurrence is rare after autologous bone marrow transplantation (BMT) with only five published reports in the literature. We report two cases of post-transplant lymphoproliferative disorder occurring after autologous BMT for Hodgkin's disease and non-Hodgkin's lymphoma. Post-transplant lymphoproliferative disorders can occur after autologous BMT and should be included in the differential diagnosis of patients with persistent fever, adenopathy or pulmonary infiltrates.
Hauke
R J
RJ
Department of Medicine, University of Nebraska Medical Center, Omaha 68198-8065, USA.
Greiner
T C
TC
Smir
B N
BN
Vose
J M
JM
Tarantolo
S R
SR
Bashir
R M
RM
Bierman
P J
PJ
D000328:Adult; D000368:Aged; D016026:Bone Marrow Transplantation / Q000009:adverse effects*; D005260:Female; D006566:Herpesviridae Infections / Q000209:etiology*; D004854:Herpesvirus 4, Human; D006801:Humans; D008232:Lymphoproliferative Disorders / Q000209:etiology*; D008297:Male; D014182:Transplantation, Autologous; D014412:Tumor Virus Infections / Q000209:etiology*