New polyketides from the sponge Plakortis sp.
Fractionation of the MeOH extract of the sponge Plakortis sp. collected around the Amirantes Islands yielded four novel polyketides (4-7). The structures have been established by a detailed highfield 2D NMR study.
Laboratory of Bio-organic Chemistry, Department of Organic Chemistry, Faculty of Sciences, CP 160/07, University of Brussels, 50 Av. F.D. Roosevelt, B-1050 Brussels, Belgium. braekman@ulb.ac.be
J C
JC
Braekman
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Daloze
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De Groote
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JB
Fernandes
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RW
Van Soest
D000818:Animals; D000970:Antineoplastic Agents / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity; D001156:Artemia; D004146:Dioxanes / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity; D004354:Drug Screening Assays, Antitumor; D005663:Furans / Q000302:isolation & purification* / Q000494:pharmacology / Q000633:toxicity; D007928:Lethal Dose 50; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D011161:Porifera / Q000737:chemistry*; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet
D000970:Antineoplastic Agents; D004146:Dioxanes; D005663:Furans