[Excitation of the hydrogen bond by the energy of hydrolysis of adenosine-5'-triphosphate].
The model of muscle contraction suggested in [1] is based on the hypothesis that the first step of the conversion of chemical energy delta E (which is stored in adenosine-5'-triphosphate) is the excitation of the hydrogen bond in the actin-myosin system with a simultaneous hydrolysis of the adenosine-5'-triphosphate molecule. As a consequence, the potential barrier is decreased, and the break of the macroergic bond adenosine-5'-triphosphate-phosphate is facilitated. With the delta E value exceeding the excitation energy of the H-bond, this process represents an exothermic reaction. A simple model of this process is constructed, and its probability depending on temperature and the mutual position of the H-bond and the adenosine-5'-triphosphate molecule is estimated.
Bespalova
S V
SV
Donetsk State University, Ukraine.
Tolpygo
K B
KB
D000255:Adenosine Triphosphate / Q000378:metabolism*; D000818:Animals; D004734:Energy Metabolism; D006859:Hydrogen; D006868:Hydrolysis; D008954:Models, Biological; D008962:Models, Theoretical; D009119:Muscle Contraction
D006859:Hydrogen; D000255:Adenosine Triphosphate