The impact of intrauterine contraceptive devices on cytological findings from routine Pap smear testing.
OBJECTIVE
To evaluate the impact of intrauterine contraceptive device (IUCD) use on the interpretation of routine Pap smears.


METHODS
A retrospective case-control study.


METHODS
During a 2-year period, we evaluated the Papanicolaou (Pap) tests of 452 consecutive asymptomatic women of childbearing age who used a copper IUCD (study group), and 452 matched controls who practiced no contraceptive methods (control group).


RESULTS
Inflammatory exudate, inflammatory epithelial changes or extensive metaplastic cells were more commonly encountered among the IUCD user as compared with non-users (p < 0.05). No difference was noted in the detection rates of cervical squamous intraepithelial lesions in the two study groups.


CONCLUSIONS
It can therefore be concluded that the use of an IUCD does not increase the incidence of squamous intraepithelial lesions. Any abnormal Pap smear in an IUCD user should first be repeated after local vaginal treatment, if only to temporarily palliate the inflammatory cellular reaction which impedes unequivocal interpretation of the routine Pap smear.
Kaplan
B
B
Department of Obstetrics and Gynecology, Rabin Medical Center, Petah Tikva, Israel.
Orvieto
R
R
Hirsch
M
M
Rabinerson
D
D
Braslavski
D
D
Bar-Hava
I
I
Ben-Rafael
Z
Z
D000328:Adult; D016022:Case-Control Studies; D003300:Copper; D005260:Female; D006801:Humans; D007434:Intrauterine Devices / Q000009:adverse effects*; D007557:Israel; D065006:Papanicolaou Test; D012189:Retrospective Studies; D014599:Uterus / Q000166:cytology*; D014626:Vaginal Smears; D016387:Women's Health
D003300:Copper