May-Hegglin anomaly: a case of vaginal delivery when both mother and fetus are affected.
May-Hegglin anomaly is a rare, autosomal dominant disorder characterized by thrombocytopenia and a variable bleeding tendency. In almost all the case reports in the recent literature, platelet transfusion and cesarean section were performed to avoid maternal and neonatal bleeding. We present a case of a woman with May-Hegglin anomaly who had no history of a bleeding tendency. She had a vaginal delivery and a platelet count of 16,000/mm3; the neonate's platelet count was 35,000/mm3. There were no complications. We advocate a reappraisal of basing platelet transfusion and mode of delivery on the platelet count in patients with May-Hegglin anomaly.
Urato
A C
AC
Brigham and Women's Hospital, Boston, Massachusetts, USA.
Repke
J T
JT
D000328:Adult; D001760:Bleeding Time; D036861:Delivery, Obstetric / Q000379:methods*; D005260:Female; D005315:Fetal Diseases / Q000235:genetics / Q000628:therapy*; D005799:Genes, Dominant; D006801:Humans; D010976:Platelet Count; D017713:Platelet Transfusion; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000628:therapy*; D013921:Thrombocytopenia / Q000235:genetics / Q000628:therapy*; D014621:Vagina