Synaptic plasticity: keeping synapses under control.
Recent studies have confirmed that a retrograde signal is produced at the neuromuscular junction that can adjust the efficacy of transmission to meet long-term changing needs. Genetic manipulations in Drosophila have begun to define the circumstances in which such signals are generated and how they act.
Department of Neurosciences Case Western Reserve University School of Medicine 10900 Euclid Avenue, Cleveland, Ohio, 44106, USA.
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Landmesser
D000818:Animals; D004330:Drosophila / Q000235:genetics / Q000502:physiology; D008959:Models, Neurological; D009469:Neuromuscular Junction / Q000502:physiology*; D009473:Neuronal Plasticity / Q000502:physiology*; D013569:Synapses / Q000502:physiology*; D009435:Synaptic Transmission / Q000502:physiology