Experimental infection in SPF kittens with a particular calicivirus strain originally isolated from lion.
Two SPF kittens were experimentally infected via the intranasal route with a strain of calicivirus originally isolated from sick lion suffering from vesicular disease. Fever, 40.3 degrees C and 40.7 degrees C, and vesicular formation in tongue and snout were reproduced in both kittens. The infected virus was recovered from nasal, oral and rectal swabs. A longer duration of virus recovery was proved with oral swab samples taken from 1 to 10 and 12 days post infection. This suggests that tongue and oral tissues are the main tissues for virus multiplication.
Kadoi
K
K
Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Kanagawa, Japan.
Kamata
H
H
Ohba
S
S
Satoh
T
T
Inaba
Y
Y
D000281:Administration, Intranasal; D000367:Age Factors; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D000918:Antibody Specificity; D002139:Caliciviridae / Q000145:classification / Q000302:isolation & purification; D017250:Caliciviridae Infections / Q000276:immunology / Q000662:veterinary* / Q000821:virology; D002371:Cat Diseases / Q000821:virology*; D002415:Cats; D005334:Fever / Q000662:veterinary / Q000821:virology; D008045:Lions / Q000821:virology; D009666:Nose / Q000473:pathology / Q000821:virology; D013047:Specific Pathogen-Free Organisms; D013997:Time Factors; D014059:Tongue / Q000473:pathology
D000914:Antibodies, Viral