An unusual exposure to methyl bromide leading to fatality.
BACKGROUND
Methyl bromide has been responsible for deaths that usually occur from its accidental inhalation during fumigation.


METHODS
We report an accidental fatality that occurred after methyl bromide seeped through underground conduits from a fumigated building to an adjacent guest house on the same property. The patient developed refractory seizures, intermittent fever, and multiorgan system failure before dying 19 days after exposure. The initial serum bromide was 27 mg/dL. Postmortem analysis detected methyl bromide concentrations of 2.9 mg/dL in the blood, 1.7 mg/dL in the bile, 24 micrograms/g in the liver, and 28 micrograms/g in the adipose tissue.


CONCLUSIONS
Methyl bromide, although applied under acceptable safety standards, led to the inadvertent death of a young woman. Extreme care must be used when fumigating to insure no unsuspected seepage routes exist.
California Poison Control System, Sacramento Division, University of California Davis Medical Center, USA. horowiza@ohsu.edu
B Z
BZ
Horowitz
T E
TE
Albertson
M
M
O'Malley
E J
EJ
Swenson
D000328:Adult; D017809:Fatal Outcome; D005260:Female; D005651:Fumigation / Q000009:adverse effects*; D006801:Humans; D006842:Hydrocarbons, Brominated / Q000032:analysis / Q000506:poisoning*; D009102:Multiple Organ Failure / Q000139:chemically induced*; D012640:Seizures / Q000139:chemically induced
D006842:Hydrocarbons, Brominated; C005218:methyl bromide