Pediatric renal transplantation--Indian experience.
OBJECTIVE
To analyze our experience with renal transplantation in children with end-stage renal disease (ESRD) in India.


METHODS
Retrospective study.


METHODS
Over the last 7.5 years, 27 renal transplants were performed on children below 12 years of age, 8 children were less than 6 years old, 19 were between 6 and 12 years of age. Sixteen children had underlying glomerular disease while eleven had tubulointerstitial renal disease. Transperitoneal approach was used in smaller recipients weighing less than 12 kg. Extraperitoneal approach was used in the remainder. Triple immunosuppression with Cyclosporine, Azathioprine and Steroids was used in all cases.


RESULTS
Follow-up period ranged from 6 months to 7.5 years (mean 3.7 years). There were 10 episodes of acute rejection. Three cases of acute rejection failed to respond to therapy. No surgical complications were encountered. Graft survival was 73.2% at one year and 71% at two years. Satisfactory rehabilitation was achieved in children with functioning grafts.


CONCLUSIONS
Renal transplantation in children in India offers an acceptable choice in ESRD as anywhere in the world.
Department of Pediatrics, Manipal Hospital, Bangalore.
K
K
Phadke
S
S
Ballal
K
K
Venkatesh
S
S
Sundar
D002648:Child; D002675:Child, Preschool; D005260:Female; D005500:Follow-Up Studies; D006085:Graft Survival; D006801:Humans; D007194:India; D007223:Infant; D007676:Kidney Failure, Chronic / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D008297:Male; D012189:Retrospective Studies; D015996:Survival Rate