[Serum erythropoietin concentration in women with uterine or ovarian tumors].
Patients with uterine or ovarian tumors frequently develop anaemia. Causes of anaemia in these patients are still not fully understood. We assessed serum erythropoietin (EPO) concentration in 70 women with benign or malignant uterine or ovarian tumors and in 43 control women. Thirteen women out of 50 with benign and 7 out of 20 with malignant tumors (26% and 35% respectively) were anaemic. In patients with benign tumors serum EPO concentrations did not differ from that in control subjects. In patients with malignant tumors plasma EPO was inappropriately low with respect to the haemoglobin concentration. From results obtained in this study it seems, that uterine or ovarian malignancy exerts a suppressive effect on EPO secretion. Inappropriately low EPO plasma concentration may account for the anaemia frequently occurring in these women.
Kliniki Nefrologii, Endokrynologii i Chorób Przemiany Materii, Slaskiej Akademii Medycznej.
J
J
Chudek
A
A
Wiecek
F
F
Kokot
A
A
Grochal
J
J
Switała
J
J
Kanwiszer
D000328:Adult; D000740:Anemia / Q000097:blood* / Q000175:diagnosis / Q000209:etiology*; D004921:Erythropoietin / Q000097:blood*; D005260:Female; D006801:Humans; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000097:blood / Q000150:complications*; D014594:Uterine Neoplasms / Q000097:blood / Q000150:complications*
D004921:Erythropoietin