Perthes disease affecting three female first-degree relatives.
Perthes disease has an incidence of 1 in 4,750 live births (1 in 3,000 boys, but only 1 in 11,800 girls). Although there is evidence for a genetic predisposition to Perthes disease, more than two family members are rarely affected. We report the first recorded case of Perthes disease affecting three female first-degree relatives.
Department of Paediatric Orthopaedics, Sheffield Children's Hospital, Western Bank, United Kingdom.
J P
JP
Livesey
S M
SM
Hay
M J
MJ
Bell
D002648:Child; D002675:Child, Preschool; D005260:Female; D006621:Hip Joint / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D007873:Legg-Calve-Perthes Disease / Q000000981:diagnostic imaging / Q000235:genetics* / Q000601:surgery; D010375:Pedigree; D011859:Radiography; D006113:United Kingdom