T cell repertoire of human umbilical cord blood.
Umbilical cord blood T cells are less functional. Different explanations have been proposed. In this study we analyze the Vbeta T cell cord blood repertoire. All the Vbeta families are expressed. We found only the overexpression of three Vbeta: Vbeta 5-1, Vbeta 5-2, Vbeta 21-2.
Cell Therapy Unit, ETS St-Louis, Paris, France.
J P
JP
Marolleau
B
B
Ternaux
L
L
Dal Cortivo
Y
Y
Brossard
E
E
Gluckman
M
M
Benbunan
D000328:Adult; D005312:Fetal Blood / Q000737:chemistry / Q000166:cytology*; D006801:Humans; D007231:Infant, Newborn; D016693:Receptors, Antigen, T-Cell, alpha-beta / Q000032:analysis; D013601:T-Lymphocytes / Q000737:chemistry / Q000166:cytology*
D016693:Receptors, Antigen, T-Cell, alpha-beta