Respiratory syncytial virus RNA in cells from the peripheral blood during acute infection.
It is not known whether respiratory syncytial virus spreads beyond the respiratory tract. With the use of reverse transcriptase polymerase chain reaction, we found viral and transcribed RNA in cells from the arterial blood of four children with bronchiolitis but none in serum or cerebrospinal fluid. Respiratory syncytial virus might therefore spread outside the respiratory tract.
O'Donnell
D R
DR
National Heart and Lung Institute, London, United Kingdom.
McGarvey
M J
MJ
Tully
J M
JM
Balfour-Lynn
I M
IM
Openshaw
P J
PJ
D001990:Bronchiolitis, Viral / Q000097:blood*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007963:Leukocytes, Mononuclear / Q000821:virology; D008297:Male; D016133:Polymerase Chain Reaction; D012333:RNA, Messenger / Q000097:blood; D012367:RNA, Viral / Q000097:blood*; D018357:Respiratory Syncytial Virus Infections / Q000097:blood*; D018113:Respiratory Syncytial Virus, Human / Q000235:genetics*
D012333:RNA, Messenger; D012367:RNA, Viral