Morphometry of fine structural alterations of hepatocytes of Japanese monkeys under fasting stress.
The fine structural alterations of hepatocytes of Japanese monkeys under 4 days of fasting stress were analyzed morphometrically. One of the conspicuous alterations was the enlargement of mitochondria. The average diameter of mitochondria in fasting group increased to approximately 1.89-fold of that in control group, though their number did not change. The number of peroxisomes was 1.36-fold of that in control, though their area did not change. In addition, many of r-ER were swollen and were vesiculated. The appearance of bundle of actin-like stress fiber also increased in the fasting animals. The glycogen area as well as liver weight decreased in fasting group.
Yang
Y G
YG
Department of Veterinary Anatomy, Faculty of Agriculture, Yamaguchi University, Japan.
Makita
T
T
D000818:Animals; D018870:Endoplasmic Reticulum, Rough / Q000473:pathology / Q000648:ultrastructure; D005215:Fasting / Q000009:adverse effects*; D007564:Japan; D008099:Liver / Q000473:pathology / Q000648:ultrastructure*; D008251:Macaca; D008930:Mitochondria, Liver / Q000473:pathology / Q000648:ultrastructure*; D012016:Reference Values; D013312:Stress, Physiological / Q000209:etiology / Q000473:pathology*