3-Deoxy-D-myo-inositol 1-phosphate, 1-phosphonate, and ether lipid analogues as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell growth.
Drug Discovery Program, Georgetown University Medical Center, 3970 Reservoir Road NW, Washington, D.C., 20007, USA.
L
L
Qiao
F
F
Nan
M
M
Kunkel
A
A
Gallegos
G
G
Powis
A P
AP
Kozikowski
D000818:Animals; D002417:Cattle; D002455:Cell Division / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D004791:Enzyme Inhibitors / Q000138:chemical synthesis* / Q000494:pharmacology; D006801:Humans; D007295:Inositol Phosphates / Q000138:chemical synthesis* / Q000494:pharmacology; D008055:Lipids / Q000138:chemical synthesis* / Q000494:pharmacology; D051379:Mice; D009368:Neoplasm Transplantation; D063065:Organophosphonates / Q000138:chemical synthesis* / Q000494:pharmacology; D000081082:Phosphoinositide-3 Kinase Inhibitors; D015398:Signal Transduction / Q000502:physiology*; D014407:Tumor Cells, Cultured
D004791:Enzyme Inhibitors; D007295:Inositol Phosphates; D008055:Lipids; D063065:Organophosphonates; D000081082:Phosphoinositide-3 Kinase Inhibitors