Analysis of surface markers on CD34+ cells, isolated from cord blood and G-CSF primed peripheral blood.
We report a comparative study of the expression of multilineage and adhesion molecules on CD34+ cells isolated from human umbilical cord blood (CB) and G-CSF-mobilized peripheral blood progenitor cells (PBPC) from healthy volunteers. The major difference found between the two sources of CD34+ populations was the expression of CD54 molecule, which was higher in CB in comparison to PBPC.
Barbosa
I L
IL
Serviço de Imuno-Hemoterapia, Instituto Português de Oncologia, Porto.
de Sousa
M E
ME
Godinho
M I
MI
Teixeira
A M
AM
Carvalhais
A
A
D015703:Antigens, CD / Q000032:analysis; D018952:Antigens, CD34 / Q000032:analysis*; D015415:Biomarkers; D005312:Fetal Blood / Q000737:chemistry / Q000166:cytology*; D016179:Granulocyte Colony-Stimulating Factor / Q000494:pharmacology*; D006684:HLA-DR Antigens / Q000032:analysis; D006412:Hematopoietic Stem Cells / Q000187:drug effects*; D006801:Humans; D013499:Surface Properties
D015703:Antigens, CD; D018952:Antigens, CD34; D015415:Biomarkers; D006684:HLA-DR Antigens; D016179:Granulocyte Colony-Stimulating Factor