Flow cytometry detection of intracytoplasmic cytokines after Neoral or sirolimus intake is an informative tool for monitoring in vivo immunosuppressive efficacy in renal transplant recipients.
Tkaczuk
J
J
Immunology Department, Rangueil University Hospital, Toulouse, France.
Rostaing
L
L
Puyoo
O
O
Peres
C
C
Abbal
M
M
Durand
D
D
Ohayon
E
E
D002478:Cells, Cultured; D016572:Cyclosporine / Q000627:therapeutic use*; D016207:Cytokines / Q000096:biosynthesis*; D016903:Drug Monitoring; D005434:Flow Cytometry / Q000379:methods; D006801:Humans; D007165:Immunosuppression Therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D015759:Ionomycin / Q000494:pharmacology; D016030:Kidney Transplantation / Q000276:immunology*; D007700:Kinetics; D015166:Monitoring, Immunologic; D011090:Polyenes / Q000627:therapeutic use*; D012016:Reference Values; D020123:Sirolimus; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D018417:Th1 Cells / Q000187:drug effects / Q000276:immunology*; D018418:Th2 Cells / Q000187:drug effects / Q000276:immunology*; D013997:Time Factors
D016207:Cytokines; D007166:Immunosuppressive Agents; D011090:Polyenes; D015759:Ionomycin; D016572:Cyclosporine; D013755:Tetradecanoylphorbol Acetate; D020123:Sirolimus