Clinical features and long-term follow-up of 20 cases of parakeratosis pustulosa.
We report the clinical features and long-term follow-up of 20 pediatric patients with parakeratosis pustulosa (PKP). In eight children PKP was considered as a clinical manifestation of psoriasis. Of these, three children had skin psoriasis at the time of our observation, two developed nail psoriasis, and three developed psoriatic pitting during follow-up. Parakeratosis pustulosa was considered a symptom of allergic contact dermatitis in four patients, whereas atopic dermatitis was possibly responsible for PKP in two patients. A complete recovery from disease was observed in 11 patients. The results of our study suggest that PKP is not a single entity but rather represents a nail symptom that can be produced by several inflammatory diseases, including nail psoriasis, atopic dermatitis, and contact dermatitis.
Department of Dermatology, University of Bologna, Italy.
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Tosti
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Peluso
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Zucchelli
D000293:Adolescent; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D008297:Male; D009260:Nail Diseases / Q000175:diagnosis*; D010241:Parakeratosis / Q000175:diagnosis*; D011565:Psoriasis / Q000175:diagnosis; D012867:Skin / Q000473:pathology; D013997:Time Factors