Treatment of oral chronic graft-versus-host disease with PUVA therapy: case report and literature review.
Chronic graft-versus-host disease commonly appears with oral manifestations subsequent to allogeneic bone marrow transplantation. These manifestations include leukoplakia, mucosal atrophy, erythema, ulcers, and xerostomia. Some lesions are resistant to treatment with immunosuppressive medications. Ultraviolet A irradiation therapy with oral psoralen has been shown to be effective in treating these resistant lesions. This article presents a review of the literature and a case report.
Redding
S W
SW
Department of General Dentistry, University of Texas Health Science Center, San Antonio, USA.
Callander
N S
NS
Haveman
C W
CW
Leonard
D L
DL
D000284:Administration, Oral; D001284:Atrophy; D016026:Bone Marrow Transplantation / Q000009:adverse effects; D004351:Drug Resistance; D004890:Erythema / Q000188:drug therapy / Q000276:immunology; D011564:Furocoumarins / Q000008:administration & dosage / Q000627:therapeutic use; D006086:Graft vs Host Disease / Q000188:drug therapy*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007972:Leukoplakia, Oral / Q000188:drug therapy / Q000276:immunology; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000188:drug therapy* / Q000276:immunology; D009061:Mouth Mucosa / Q000473:pathology; D019226:Oral Ulcer / Q000188:drug therapy / Q000276:immunology; D011701:PUVA Therapy; D017319:Photosensitizing Agents / Q000008:administration & dosage / Q000627:therapeutic use; D014184:Transplantation, Homologous; D014987:Xerostomia / Q000188:drug therapy / Q000276:immunology
D011564:Furocoumarins; D007166:Immunosuppressive Agents; D017319:Photosensitizing Agents