[Good response in case of hepatocellular carcinoma; a case report of interdisciplinary local therapy].
A 47-year-old male patient with chronic hepatitis had a high AFP level during the follow-up period. Abdominal CT revealed at S5, which led to a diagnosis of hepatocellular carcinoma. In August 1992, partial resection of S5 was performed, and ethanol was injected into the tumor at S2. In July 1993, recurrent tumors were observed at S5 and S3. PEIT was performed for each lesion. In December 1994, multiple recurrence was observed and 4 mg SMANCS was injected through the proper hepatic artery. In July 1995, another 4 mg of SMANCS was injected into the tumors. In June 1996, only a 20 mm lesion at S5 remained while the other lesions disappeared. Under general anesthesia, the patient underwent percutaneous microwave tumor coagulation. In December 1997, the AFP level was normal, and imaging revealed disappearance of the recurrent tumor. Selection of local therapy for hepatocellular carcinoma achieved long survival in our case considering the QOL and frequent therapy administration.
Dept. of Surgery, Toyonaka Municipal Hospital.
T
T
Niinobu
T
T
Shibata
N
N
Shibata
T
T
Takada
M
M
Kitada
Y
Y
Tsukahara
S
S
Hata
K
K
Ikeda
H
H
Hayashida
M
M
Ogawa
N
N
Hayashi
K
K
Akazawa
M
M
Takami
D000970:Antineoplastic Agents / Q000008:administration & dosage*; D006528:Carcinoma, Hepatocellular / Q000601:surgery / Q000628:therapy*; D003131:Combined Modality Therapy; D004564:Electrocoagulation / Q000379:methods; D000431:Ethanol / Q000008:administration & dosage*; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D015552:Injections, Intralesional; D008113:Liver Neoplasms / Q000601:surgery / Q000628:therapy*; D008297:Male; D008299:Maleic Anhydrides / Q000008:administration & dosage*; D008872:Microwaves / Q000627:therapeutic use; D008875:Middle Aged; D011137:Polystyrenes / Q000008:administration & dosage*; D009353:Zinostatin / Q000008:administration & dosage / Q000031:analogs & derivatives*
D000970:Antineoplastic Agents; D008299:Maleic Anhydrides; D011137:Polystyrenes; C035755:poly(maleic acid-styrene)neocarzinostatin; D000431:Ethanol; D009353:Zinostatin