[The reaction of the nasal mucosa in allergic rhinitis to cold saline stimulus].
To clarify the nature of the reaction pattern of the nasal mucosa in allergic rhinitis, nasal lavage using a cold saline solution of 4 degrees C and a warm saline solution was attempted in 8 patients with nasal allergy to the pollen of the Japanese cedar and cypress in a non-scatter season, and the concentration of protein contents in the nasal washings was determined. The concentrations of total protein, albumin and 26 kD protein were higher in cold saline than in the warm saline lavage. In particular, the concentration of 26 kD protein was 5.3 times higher. However, the concentration was not very high compared with the value obtained by warm saline lavage in the scatter season. These findings indicate that the nasal mucosa of patients with allergic rhinitis is reactive to cold saline stimuli even in the non-scatter season.
Department of Otorhinolaryngology, Kitasato University, School of Medicine, Kanagawa.
Y
Y
Iguchi
K
K
Yao
M
M
Okamoto
M
M
Majima
D000328:Adult; D000418:Albumins / Q000032:analysis; D003080:Cold Temperature / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008970:Molecular Weight; D009093:Mucus / Q000737:chemistry; D009297:Nasal Mucosa / Q000378:metabolism / Q000503:physiopathology*; D011506:Proteins / Q000032:analysis; D006255:Rhinitis, Allergic, Seasonal / Q000378:metabolism / Q000503:physiopathology*; D012965:Sodium Chloride
D000418:Albumins; D011506:Proteins; D012965:Sodium Chloride