Cisplatin-based chemotherapy for testicular cancer in a patient with spinal muscular atrophy: a case report.
Metastatic germ-cell tumors of the testis are highly curable with cisplatin-based chemotherapy. Although cisplatin-based chemotherapy is generally well tolerated and rarely causes severe neurotoxicity, there is little information to guide the treatment of patients with neuromuscular disorders. The authors report the successful treatment of a patient with testicular cancer and spinal muscular atrophy, an inherited degenerative neuromuscular disease.
Department of Medical Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA.
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Sokol
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Hudes
D000328:Adult; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002945:Cisplatin / Q000627:therapeutic use*; D018237:Germinoma / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D008297:Male; D009134:Muscular Atrophy, Spinal / Q000150:complications*; D013736:Testicular Neoplasms / Q000150:complications* / Q000188:drug therapy*
D000970:Antineoplastic Agents; D002945:Cisplatin