Discordance between FDG uptake and technetium-99m-HMPAO brain perfusion in acute traumatic brain injury.
A 28-yr-old woman who sustained a mild traumatic brain injury had an 18F-fluorodeoxyglucose (FDG) PET brain study using coincidence imaging performed on a dual-head gamma camera (MCD version; ADAC, Milpitas, CA) followed 24 hr later by 99mTc-hexamethyl propyleneamine oxime SPECT brain perfusion imaging using a triple-head gamma camera (TRIONIX, Twinsburg, OH). The results of the SPECT brain perfusion study demonstrated decreased frontoparietal cortical brain perfusion, whereas 18F-FDG cerebral uptake was normal. Neuropsychological evaluation suggested frontal lobe involvement. This case demonstrates the possibility of discordance between brain perfusion and glucose uptake in acute mild traumatic brain injury.
Department of Radiology, St. Vincent's Hospital and Medical Center of New York, New York Medical College at Valhalla, 10011, USA.
H H
HH
Abu-Judeh
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M
Singh
J C
JC
Masdeu
H M
HM
Abdel-Dayem
D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging*; D001930:Brain Injuries / Q000000981:diagnostic imaging*; D002560:Cerebrovascular Circulation / Q000502:physiology; D005260:Female; D005462:Fluorine Radioisotopes; D019788:Fluorodeoxyglucose F18; D006801:Humans; D019275:Radiopharmaceuticals; D019690:Technetium Tc 99m Exametazime; D013997:Time Factors; D014055:Tomography, Emission-Computed; D015899:Tomography, Emission-Computed, Single-Photon
D005462:Fluorine Radioisotopes; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D019690:Technetium Tc 99m Exametazime