Inherited retinal telangiectasia with glial proliferation.
We describe five patients from a family of Pakistani origin with inherited retinal telangiectasia and glial proliferation. Characteristics of this condition include: variable visual loss; peripapillary retinal telangiectasia with vascular incompetence on fluorescein angiography; glial proliferation; cystoid macular edema or altered macular pigment; retinal hemorrhage; and abnormal electroretinopathy. We discuss the similarities with and distinguishing features from other documented conditions and the mode of inheritance.
Department of Ophthalmology, Royal Infirmary, Bradford, England.
M
M
McKibbin
W
W
Amoaku
J A
JA
Bradbury
D000328:Adult; D002648:Child; D002675:Child, Preschool; D002874:Chromosome Mapping; D002897:Chromosomes, Human, Pair 7; D004276:DNA, Satellite; D004739:England; D005260:Female; D005451:Fluorescein Angiography; D006239:Haplotypes; D006801:Humans; D008297:Male; D009457:Neuroglia / Q000473:pathology; D009898:Optic Disk / Q000473:pathology; D010154:Pakistan / Q000208:ethnology; D010781:Photography; D013683:Telangiectasia, Hereditary Hemorrhagic / Q000235:genetics* / Q000473:pathology
D004276:DNA, Satellite