Mono-inverted reciprocation of segments from two chromatids.
The paper discusses a mechanism for reciprocal translocation of midsegments between two chromatids so that one of the segments is restacked in inverted configuration. Regarding malignant cells, such process could derive from anachronistic assembly of the nuclear envelope.
USC Medical School, Los Angeles, CA 90033, USA.
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Matioli
D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D002842:Chromatids / Q000235:genetics*; D002869:Chromosome Aberrations; D008677:Metaphase; D008957:Models, Genetic; D014178:Translocation, Genetic