Lower extremity purpura associated with new-onset autoimmune hepatitis: an unusual presentation.
Autoimmune hepatitis is a chronic necroinflammatory disorder of unknown cause. The morbidity and mortality of this potentially lethal disorder can be minimized by timely diagnosis and treatment. Patients can present with a wide variety of clinical and laboratory manifestations, including high titers of antinuclear antibody and other autoantibodies commonly associated with dermatologic disorders. Overt evidence of hepatic injury can be a late finding. An unusual presentation of autoimmune hepatitis and a brief review of its clinical features are presented, with an emphasis on those findings most relevant to a practicing dermatologist.
Powers
J C
JC
Brooke Army Medical Center, Fort Sam Houston, Texas, USA.
Hill
J C
JC
Grabski
W J
WJ
D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D019693:Hepatitis, Autoimmune / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007868:Leg Dermatoses / Q000276:immunology* / Q000473:pathology; D011693:Purpura / Q000276:immunology* / Q000473:pathology