Palliative management of brain metastases.
The development of brain metastases in patients with advanced cancer is associated with increased morbidity and diminished longevity. Palliative treatment modalities focus predominantly on improving quality of life. Well-established beneficial treatments include the use of corticosteroids, radiotherapy, and surgery. Management issues that require further exploration and clarification include the dosages of glucocorticoids, the prophylactic use of anticonvulsants and the indications for radiosurgery.
Oneschuk
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D
Edmonton Regional Palliative Care Programme, Grey Nuns Community Health Centre, Canada.
Bruera
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E
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000970:Antineoplastic Agents / Q000627:therapeutic use; D001932:Brain Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000556:secondary* / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D010166:Palliative Care / Q000379:methods*; D011878:Radiotherapy / Q000379:methods; D013514:Surgical Procedures, Operative; D015996:Survival Rate
D000305:Adrenal Cortex Hormones; D000970:Antineoplastic Agents