Radiotherapy in vertebral tumors. Indications and limits: a report on 28 cases of Ewing's sarcoma of the spine.
After brief notes on techniques used to radiate the spine, its indications and the limits of doses required by its adjacency to the spinal cord, our experience in the treatment of 28 patients with a diagnosis of Ewing's sarcoma localized in the spine, not metastatic at onset, that came to our observation between 1980 and 1994 is reported. All of the patients were treated by chemotherapy. As for local treatment radiotherapy was performed in all of the cases, in 50% of cases it was associated with surgery (6 laminectomies, 6 excisions, and 2 vertebrectomies). Five-year survival rate was 43.5%. The prognosis of this group of patients was intermediate among forms localized in the limbs and those localized in the pelvis. There is a greater frequency of cerebral (20%) and skeletal metastases (55%) as compared to the disease that occurred in other sites where secondary pulmonary localizations generally prevailed. Local control was similar for disease occurring in other sites despite the need to deliver doses that were lower than those typically used for this pathology in regions above the cauda.
Istituto di Radioterapia L. Galvani, Università, Bologna.
E
E
Barbieri
G
G
Chiaulon
F
F
Bunkeila
C
C
Putti
G
G
Frezza
S
S
Neri
S
S
Boriani
M
M
Campanacci
L
L
Babini
D000293:Adolescent; D000328:Adult; D002574:Cervical Vertebrae; D002648:Child; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007796:Laminectomy; D008159:Lumbar Vertebrae; D008297:Male; D009362:Neoplasm Metastasis; D011879:Radiotherapy Dosage; D012447:Sacrum; D012512:Sarcoma, Ewing / Q000532:radiotherapy* / Q000601:surgery; D013125:Spinal Neoplasms / Q000532:radiotherapy* / Q000601:surgery; D013904:Thoracic Vertebrae; D013997:Time Factors