[Antidepressants and sexual stimulation: the correlation].
The purpose of this study is to correlate antidepressant treatment with sexual stimulation. The first part of this paper tries to describe some physiologic aspects of the sexual function. This complex subject includes several neuromediators which belong to adrenergic, cholinergic, dopaminergic and serotoninergic systems. A double-blind study shows that viloxazine, an atypical antidepressant, could act specifically on sex drive by desinhibiting effect. A precise study concludes that moclobemide improve significantly all components of sexual function. The numerous side effects of doxépine is a hindrance to its prescription. More precise studies about viloxazine and moclobemide suggest that both could have a specific effect on different components of sexual activity. In the second part of this paper, we consider the concept of "corrector". These drugs are numerous, however their prescriptions are not very wide spread: yohimbine, cyproheptadine, amantadine, bethanechol.
Psychiatre des Hôpitaux, EPS Ville Evrard, Neuilly-sur-Marne.
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S
Chebili
A
A
Abaoub
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B
Mezouane
J F
JF
Le Goff
D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D001549:Benzamides / Q000009:adverse effects / Q000627:therapeutic use; D003866:Depressive Disorder / Q000188:drug therapy* / Q000523:psychology; D004316:Doxepin / Q000009:adverse effects / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007989:Libido / Q000187:drug effects*; D008297:Male; D020912:Moclobemide; D012725:Sexual Behavior / Q000187:drug effects*; D020018:Sexual Dysfunctions, Psychological / Q000139:chemically induced* / Q000188:drug therapy; D013268:Stimulation, Chemical; D014745:Viloxazine / Q000009:adverse effects / Q000627:therapeutic use
D000928:Antidepressive Agents; D001549:Benzamides; D004316:Doxepin; D014745:Viloxazine; D020912:Moclobemide