A simple and regioselective synthesis of 13C-methyl-labeled thymidine.
A convenient and efficient procedure for the synthesis of 13C methyl- labeled thymidine by way of lithiation of t-butyldimethylsilyl protected 2'-deoxyuridine is described.
Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, W. Lafayette, IN 47907, USA.
M
M
Ahmadian
D E
DE
Bergstrom
D002247:Carbon Isotopes; D009682:Magnetic Resonance Spectroscopy; D008745:Methylation; D008956:Models, Chemical; D013936:Thymidine / Q000031:analogs & derivatives* / Q000138:chemical synthesis
D002247:Carbon Isotopes; D013936:Thymidine