Nonlinear characteristics of electrically evoked otoacoustic emissions.
To further our knowledge of outer hair cell nonlinearities, we measured the dependence of the electrically-evoked otoacoustic emissions (EEOEs) on current level for a wide range of electrical frequencies. Alternating electrical current was delivered into the scala media of the gerbil cochlea while the EEOE was measured with a probe-tube microphone. While the EEOE scaled linearly with current level for many frequencies and current levels, notable exceptions occurred. For frequencies below 300 Hz and currents above 20-30 microA(peak), the gain (primary EEOE magnitude divided by the current level) increased abruptly. For higher frequencies, the gain often increased slightly with increasing current of up to 30-50 microA(peak), but decreased at even higher current levels. We also investigated the enhancement of the EEOE due to simultaneous acoustic stimulation. The enhancement of the EEOE was relatively insensitive to current level with little change in enhancement for current levels up to 20 microA(peak). For current levels above approximately 40 microA(peak), the enhancement decreased slightly.
Hearing Research Center and Department of Biomedical Engineering, Boston University, MA 02215, USA. hhn@enga.bu.edu
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D000161:Acoustic Stimulation; D000818:Animals; D003054:Cochlear Implants; D004558:Electric Stimulation; D016057:Evoked Potentials, Auditory, Brain Stem / Q000502:physiology*; D005849:Gerbillinae; D018072:Hair Cells, Auditory, Outer / Q000502:physiology*; D017084:Otoacoustic Emissions, Spontaneous