Epithelioid leiomyosarcoma of the larynx.
BACKGROUND
Tumors of smooth muscle origin are rare in the upper aerodigestive tract, due to the paucity of smooth muscle in the area. A review of the literature revealed 34 reported cases of leiomyoma, 9 cases of leiomyosarcoma, and only 2 cases of epithelioid leiomyoma arising in the larynx.


METHODS
A case report of an epithelioid leiomyosarcoma arising in the right piriform fossa of a 38-year-old man is presented.


RESULTS
The tumor was treated with conservative surgical resection and postoperative radiotherapy. There was no evidence of locoregional recurrence 2 years postsurgery, and laryngeal function was preserved.


CONCLUSIONS
To our knowledge, this is the third case of a laryngeal epithelioid smooth muscle tumor to be reported in the world literature and the only documentation of an epithelioid leiomyosarcoma arising in the larynx.
Sindwani
R
R
Department of Otolaryngology, St. Joseph's Health Centre, University of Western Ontario, London, Canada.
Matthews
T W
TW
Thomas
J
J
Venkatesan
V M
VM
D000328:Adult; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D007825:Laryngectomy; D007890:Leiomyosarcoma / Q000175:diagnosis* / Q000556:secondary / Q000628:therapy*; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008297:Male; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed