[A case of report--interferon therapy is useful for chronic hepatitis C with human immunodeficiency virus infection].
A 42-year-old male type A hemophiliae who been using coagulates since 1971 was diagnosed Human Immunodeficiency Virus (HIV) positive in 1993. Medical history included liver disfunction in 1987, with chronic hepatitis C (CHC) diagnosed in 1989. He was admitted to the hospital in October, 1994 because of general fatigue. Serum transaminase was elevated, CD4 was 221/micro L, and CD8 was 990. CD4/CD8 ratio was 0.2. HCV was of genotype 2b and 10(6) copies/50 microL, 8 week-Interferon (IFN)-beta treatment was started. HCV RNA was eliminated by week 8 and was sustained for one year with no severe side effects. With careful patient screening, IFN therapy for CHC with HIV may be an effective treatment.
Department of General Medicine, Kyushu University Hospital.
K
K
Yamashita
J
J
Hayashi
T
T
Yamamoto
Y
Y
Pei
K
K
Ise
S
S
Kashiwagi
D000328:Adult; D015658:HIV Infections / Q000150:complications*; D006467:Hemophilia A / Q000150:complications; D019698:Hepatitis C, Chronic / Q000628:therapy*; D006801:Humans; D016899:Interferon-beta / Q000627:therapeutic use*; D008297:Male
D016899:Interferon-beta