Lymphoma associated bone marrow necrosis with raised anticardiolipin antibody.
A case of high grade B cell lymphoma presented with bone marrow necrosis, followed by development of extensive marrow fibrosis, the evolution of which was documented by serial magnetic resonance imaging and bone marrow trephine histology. A markedly raised anticardiolipin antibody titre at diagnosis suggests that lymphoma associated antiphospholipid syndrome may have contributed to the aetiology of the bone marrow necrosis.
Department of Haematology, Leicester Royal Infirmary, UK.
P T
PT
Murphy
M
M
Sivakumaran
M C
MC
Casey
A
A
Liddicoat
J K
JK
Wood
D000368:Aged; D016736:Antiphospholipid Syndrome / Q000209:etiology*; D001853:Bone Marrow / Q000473:pathology*; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications*; D008228:Lymphoma, Non-Hodgkin / Q000150:complications*; D008279:Magnetic Resonance Imaging; D008297:Male; D009336:Necrosis; D010257:Paraneoplastic Syndromes / Q000209:etiology*