[Aspergillus antigen detection: comparison of a new sandwich ELISA with the latex agglutination test in patients with histologically proven invasive aspergillosis].
A new sandwich antigen enzyme-linked immunosorbent assay (ELISA) for the detection of Aspergillus galactomannan in blood plasma was compared with the latex-agglutination test by investigation of six patients with histologically proven invasive aspergillosis. The ELISA gave positive results in all six patients while the latex test recognized 5/6 as positive. On an average the antigen ELISA gave positive results 19 days earlier than the latex test.
Institut für Medizinische Mikrobiologie und Hygiene, Universität Freiburg, Deutschland, Germany.
J
J
Herrmann
A
A
Gugel
H
H
Freidank
H
H
Bertz
J
J
Finke
D000293:Adolescent; D000328:Adult; D000946:Antigens, Fungal / Q000097:blood*; D001228:Aspergillosis / Q000175:diagnosis* / Q000473:pathology; D001230:Aspergillus / Q000276:immunology*; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D005690:Galactose / Q000031:analogs & derivatives; D006801:Humans; D007841:Latex Fixation Tests; D008297:Male; D008351:Mannans / Q000097:blood; D008875:Middle Aged; D012189:Retrospective Studies
D000946:Antigens, Fungal; D008351:Mannans; C012990:galactomannan; D005690:Galactose