[State of local immunity in keratoconus].
Local immunity was studied in 81 patients (146 eyes) aged 11-49 with keratoconus at different stages of the disease running different course. The concentrations of IgG, IgM, secretory IgA, lysozyme, immune complexes, C3 component of the complement, transferrin, and alpha 1-antitrypsin are increased in tears of patients with keratoconus, reflecting the activation of local immunity in this condition.
Gorskova
E N
EN
Tarasova
L N
LN
Teplova
S N
SN
Sevost'ianov
E N
EN
Alekhina
T V
TV
D000293:Adolescent; D000328:Adult; D000936:Antigen-Antibody Complex; D002648:Child; D003176:Complement C3 / Q000032:analysis; D003627:Data Interpretation, Statistical; D006801:Humans; D007136:Immunoglobulins / Q000032:analysis; D007640:Keratoconus / Q000276:immunology*; D008875:Middle Aged; D009391:Nephelometry and Turbidimetry; D013666:Tears / Q000276:immunology; D014168:Transferrin / Q000032:analysis; D000515:alpha 1-Antitrypsin / Q000032:analysis
D000936:Antigen-Antibody Complex; D003176:Complement C3; D007136:Immunoglobulins; D014168:Transferrin; D000515:alpha 1-Antitrypsin