Dynamin and its partners: a progress report.
Dynamin's role in clathrin-mediated endocytosis is now well established. Here we review new evidence from the past two years for the function of dynamin and related GTPases in other Intracellular trafficking events. We then summarize current information on the domain structure and function of this multidomain GTPase. Finally, we describe dynamin partners and their function in the context of clathrin-mediated endocytosis.
Department of Cell Biology, Scripps Research Institute, La Jolla, CA 92037, USA.
S L
SL
Schmid
M A
MA
McNiven
P
P
De Camilli
D017398:Alternative Splicing; D000595:Amino Acid Sequence; D000818:Animals; D001665:Binding Sites; D034281:Dynamins; D004705:Endocytosis; D020558:GTP Phosphohydrolases / Q000378:metabolism / Q000502:physiology*; D006863:Hydrogen-Ion Concentration; D007425:Intracellular Membranes / Q000378:metabolism; D008969:Molecular Sequence Data; D010716:Phosphatidylinositols / Q000378:metabolism; D011506:Proteins / Q000378:metabolism
D010716:Phosphatidylinositols; D011506:Proteins; D020558:GTP Phosphohydrolases; D034281:Dynamins