Ureteral obstruction secondary to indinavir in the pediatric HIV population.
Indinavir sulfate is a protease inhibitor used in the treatment of the human immunodeficiency virus (HIV). This case report describes the radiographic and urologic manifestations of indinavir urolithiasis in two pediatric patients with acquired immunodeficiency syndrome (AIDS). Management involves aggressive hydration and surgical intervention when indicated.
Noble
C B
CB
Department of Radiology, Babies & Children's Hospital of New York, 3959 Broadway, BHN 3-318, New York, NY 10032, USA.
Klein
L T
LT
Staiman
V R
VR
Neu
N
N
Hensle
T W
TW
Berdon
W E
WE
D000293:Adolescent; D003460:Crystallization; D015658:HIV Infections / Q000188:drug therapy*; D017320:HIV Protease Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D019469:Indinavir / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D011859:Radiography; D014514:Ureteral Calculi / Q000139:chemically induced* / Q000150:complications / Q000000981:diagnostic imaging; D014517:Ureteral Obstruction / Q000000981:diagnostic imaging / Q000209:etiology*
D017320:HIV Protease Inhibitors; D019469:Indinavir