[Rat testicular germ cells as a new source of estrogens].
The presence of estrogens, their function and targets in male reproductive tract are still not fully understood. Recent studies, basic and clinical indicate an important role of estrogens during germ cell development. In this study the efforts have been made to immunolocalize aromatase P450 as well as estrogen receptors within rat testis. Spermatids and spermatozoa have been found as aromatase immunopositive cells. Colocalization of estrogen receptors have also been observed. To prove the site of functional aromatase the authors used molecular complementary techniques, as described previously. In the light of literature, this article discusses also a novel, nontraditional site of estrogen synthesis and potential estrogen action within male reproductive tract.
Pracowni Endokrynologii i Hodowli Tkanek Zakładu Fizjologii Zwierzat, Instytut Zoologii, Uniwersytet Jagielloński, Kraków.
B
B
Bilińska
S
S
Carreau
D000818:Animals; D001141:Aromatase / Q000378:metabolism; D004967:Estrogens / Q000032:analysis*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D013094:Spermatozoa / Q000737:chemistry* / Q000201:enzymology; D013737:Testis / Q000737:chemistry*
D004967:Estrogens; D001141:Aromatase