[The content of the protein markers of hemato-encephalic barrier permeability in the cerebrospinal fluid in severe craniocerebral trauma].
The CSF levels of albumin, alpha 2-microglobulin and IgG were studied in patients with severe brain injury. Elevated CSF levels of albumin and alpha 2-microglobulin were found in more severe patients. The level of IgG level was within the normal range. Endogenic protease-bound alpha 2-microglobulin may cause secondary cerebral tissue lesion, by closing the vicious circle.
Kuksinskiĭ
V A
VA
Lutsik
A A
AA
Churliaev
Iu A
IuA
Lykova
O F
OF
Nikiforova
N V
NV
Martynenkov
V Ia
VIa
Bykov
K V
KV
D000208:Acute Disease; D000418:Albumins / Q000134:cerebrospinal fluid*; D015415:Biomarkers / Q000134:cerebrospinal fluid; D001812:Blood-Brain Barrier; D001930:Brain Injuries / Q000134:cerebrospinal fluid*; D002463:Cell Membrane Permeability; D002556:Cerebrospinal Fluid Proteins / Q000032:analysis*; D006801:Humans; D007074:Immunoglobulin G / Q000134:cerebrospinal fluid*; D000511:alpha-Macroglobulins / Q000134:cerebrospinal fluid*
D000418:Albumins; D015415:Biomarkers; D002556:Cerebrospinal Fluid Proteins; D007074:Immunoglobulin G; D000511:alpha-Macroglobulins