Evaluation of an avian-specific probiotic and Salmonella typhimurium-Specific antibodies on the colonization of Salmonella typhimurium in broilers.
Salmonella typhimurium colonizes the intestinal tract of poultry and causes food-borne illness in humans. Reduction of S. typhimurium colonization in the intestinal tract of poultry reduces potential carcass contamination during slaughter. The purpose of this study was to determine the effect of an avian-specific probiotic and S. typhimurium-specific antibodies on the colonization of S. typhimurium in broilers and on body weights. Broiler chicks were spray-vaccinated at the hatchery with the commercial product. Avian Pac Plus, which contains Lactobacillus acidophilus, Streptococcus faecium, ad S. typhimurium-specific antibodies. At placement, these chicks were administered Avian Pac plus in the water. Six hours postplacement, chicks were orally challenged with 1.8 x 10 (7) CFU of S. typhimurium. Chicks were administered Avian Pac Plus for two additional days postchallenge. Chicks were evaluated for S. typhimurium colonization and shedding every 3 to 4 days for the first 2 weeks and every 7 days for 6 weeks. The mean cecal and colonic concentration of S. typhimurium from the Avian Pac Plus-treated group was significantly lower at day 31 (P = 0.0001), day 38 (P = 0.0005), and day 43 (P = 0.0001) than the nontreated control group. These results indicated that a combination of Lactobacillus acidophilus, Streptococcus faecium, and S typhimurium-specific antibodies have a beneficial effect in reducing the colonization of S. typhimurium in market-aged broilers.
Department of Veterinary Preventive Medicine, Ohio State University, Columbia 43210, USA.
B
B
Promsopone
T Y
TY
Morishita
P P
PP
Aye
C W
CW
Cobb
A
A
Veldkamp
J R
JR
Clifford
D000003:Abattoirs; D000818:Animals; D000907:Antibodies, Bacterial / Q000008:administration & dosage*; D001835:Body Weight; D002645:Chickens; D015169:Colony Count, Microbial; D016984:Enterococcus faecium / Q000276:immunology*; D005766:Gastrointestinal Contents / Q000382:microbiology; D007116:Immunization, Passive; D007779:Lactobacillus acidophilus / Q000276:immunology*; D011201:Poultry Diseases / Q000517:prevention & control*; D011202:Poultry Products / Q000382:microbiology; D019936:Probiotics / Q000008:administration & dosage*; D012481:Salmonella Infections, Animal / Q000517:prevention & control*; D012486:Salmonella typhimurium / Q000276:immunology / Q000472:pathogenicity*
D000907:Antibodies, Bacterial