Antihyperlipidemic effect of hydroalcoholic extract, and polyphenolic fraction from Dracocephalum kotschyi Boiss.
Blood lipid levels in rats with hyperlipidemia resulting from high-fat feeding were determined after oral administration of hydroalcoholic extract and polyphenolic fraction of Dracocephalum kotschyi leaves. Administration of the hydroalcoholic extract and polyphenolic fraction produced a significant decrease of blood triglyceride, total cholesterol and LDL-cholesterol levels. HDL-cholesterol level was significantly increased.
Department of Pharmacognosy, Faculty of Pharmacy, Isfahan University of Medical Sciences, Iran.
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Ebrahim Sajjadi
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Movahedian Atar
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Yektaian
D000284:Administration, Oral; D000818:Animals; D005419:Flavonoids; D000960:Hypolipidemic Agents / Q000737:chemistry / Q000494:pharmacology*; D008055:Lipids / Q000097:blood; D008297:Male; D010636:Phenols; D010936:Plant Extracts / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*; D011108:Polymers; D059808:Polyphenols; D051381:Rats; D017208:Rats, Wistar
D005419:Flavonoids; D000960:Hypolipidemic Agents; D008055:Lipids; D010636:Phenols; D010936:Plant Extracts; D011108:Polymers; D059808:Polyphenols