Methotrexate for resistant chronic uveitis in children with juvenile rheumatoid arthritis.
We used low-dose methotrexate to treat seven children with juvenile rheumatoid arthritis-associated uveitis complicated by cataract and glaucoma or resistant to topical corticosteroid. The use of methotrexate decreased the severity of uveitis in six of seven patients and allowed for the discontinuation or reduction of corticosteroid drops.
Weiss
A H
AH
Department of Ophthalmology, University of Washington, Seattle, USA.
Wallace
C A
CA
Sherry
D D
DD
D000293:Adolescent; D000328:Adult; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001171:Arthritis, Juvenile / Q000150:complications* / Q000188:drug therapy; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008727:Methotrexate / Q000627:therapeutic use*; D016896:Treatment Outcome; D014605:Uveitis / Q000150:complications / Q000188:drug therapy*
D018501:Antirheumatic Agents; D007166:Immunosuppressive Agents; D008727:Methotrexate