[Stereotaxic brain biopsy in AIDS patients with neurological manifestations].
Prospective series showing the importance of computerized stereotactic brain biopsy in the management of AIDS patients neurologically symptomatic and confirmed by images. Patients undergone an algorithm step by step done by their own doctors and referred to us for stereotactic biopsy. Our protocol was opened in August 1995 and closed in December 1996. Twenty patients were biopsied. This protocol is similar to the Levy's one (Chicago IL, USA). We have got diagnosis in all cases. Lymphoma was predominant and followed by toxoplasmosis, progressive multifocal leukoencephalopathy and HIV encephalopathy. We included one patient with diploic giant cells lymphoma. Our mortality and morbidity was zero. By these results we conclude that stereotactic biopsy in AIDS patients is safe and effective.
Nasser
J A
JA
UNIFESP-Escola Paulista de Medicina, São Paulo-SP, Neurolife Laboratórios, Estereolife Neurocirurgia funcional e Estereotáxica (NLL/ELNFE), Brasil.
Confort
C I
CI
Ferraz
A
A
Esperança
J C
JC
Duarte
F
F
D015526:AIDS Dementia Complex / Q000473:pathology*; D000163:Acquired Immunodeficiency Syndrome / Q000473:pathology*; D000328:Adult; D001706:Biopsy; D006801:Humans; D007968:Leukoencephalopathy, Progressive Multifocal / Q000473:pathology*; D008223:Lymphoma / Q000473:pathology*; D016483:Lymphoma, AIDS-Related / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011446:Prospective Studies; D013238:Stereotaxic Techniques; D014057:Tomography, X-Ray Computed; D016781:Toxoplasmosis, Cerebral / Q000473:pathology*