Testicular relapse after 13 years of complete remission of acute lymphoblastic leukemia.
Girls with acute lymphoblastic leukemia appear to have a higher cure rate than boys. This is in part attributable to the reoccurrence of testicular disease in boys. Although the frequency of testicular relapse is less than 5% with current intensive therapy regimens, testicular disease remains of apparent clinical importance. Here we report an unusually late testicular relapse in an 18-year-old male after 12.7 years of continuous complete remission, and review the literature regarding this late failure.
Franck
P
P
University Children's Hospital, Department of Urology, Freiburg Medical School, Freiburg, Germany. franck@kkl200.ukl.uni-freiburg.de
Duffner
U
U
Schulze-Seemann
W
W
Riede
U
U
Dördelmann
M
M
Niemeyer
C M
CM
D000328:Adult; D006801:Humans; D008297:Male; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology* / Q000628:therapy; D012008:Recurrence; D013736:Testicular Neoplasms / Q000473:pathology* / Q000628:therapy; D013737:Testis / Q000473:pathology; D013997:Time Factors