Relationship between left ventricular hypertrophy and renal and retinal damage in untreated patients with essential hypertension.
We examined the relationship between left ventricular hypertrophy (LVH) and renal and retinal damage in 174 untreated patients with essential hypertension. As an index of renal and retinal damage, we examined proteinuria and retinal vascular change. LVH was diagnosed according to left ventricular mass obtained from echocardiography. Of the hypertensive patients, 111 patients (64%) had LVH. The incidences of proteinuria and advanced retinal vascular change were higher in patients with LVH than in those without LVH. In a multiple regression model, there was a significant positive correlation between left ventricular mass and proteinuria, as well as diastolic blood pressure, sex, age and body mass index. In conclusion, proteinuria is related to elevated left ventricular mass in patients with essential hypertension.
The Department of Internal Medicine, Nishio Municipal Hospital.
M
M
Saitoh
K
K
Matsuo
S
S
Nomoto
T
T
Kondoh
T
T
Yanagawa
Y
Y
Katoh
K
K
Hasegawa
D001794:Blood Pressure; D015992:Body Mass Index; D004452:Echocardiography; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000503:physiopathology; D017379:Hypertrophy, Left Ventricular / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D007674:Kidney Diseases / Q000150:complications* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011507:Proteinuria / Q000150:complications / Q000503:physiopathology; D012164:Retinal Diseases / Q000150:complications* / Q000503:physiopathology; D012171:Retinal Vessels / Q000473:pathology