Severe antecollis during antipsychotics treatment: a report of three cases.
1. The authors report on three patients with severe antecollis that developed after chronic treatment with antipsychotics. These patients had been treated with neuroleptics for their delusions and hallucinations. Antecollis is a rare form of tardive dystonia that has drawn little attention. To our knowledge, there have been no reports on this disorder. 2. The patients developed the symptom after receiving a number of antipsychotics for 4 months to 14 years. Neither discontinuation of antipsychotics nor administration of anticholinergic agents affected the symptom. 3. Although spontaneous improvement of dystonia was obtained after several months without any specific treatment in one patient, the symptom persisted for several years in another. The last patient could not be followed after discharge from our hospital since she and her family did not come to the hospital. 4. Severe antecollis may cause disturbances in various functions, such as vision, speaking and swallowing. Forward bending of the neck may cause inspiratory obstruction. Severe antecollis may not be unusual and psychiatrists should be aware of this symptom in routine clinical practice.
Hyogo Institute for Aging Brain and Cognitive Disorders, Himeji, Japan. maeda@hiabcd.go.jp
K
K
Maeda
T
T
Ohsaki
K
K
Kuki
K
K
Kin
M
M
Ikeda
Y
Y
Matsumoto
D000368:Aged; D014150:Antipsychotic Agents / Q000009:adverse effects*; D004409:Dyskinesia, Drug-Induced / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000523:psychology*; D005260:Female; D019416:Head Movements / Q000187:drug effects / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D009334:Neck Muscles / Q000000981:diagnostic imaging / Q000503:physiopathology; D011859:Radiography
D014150:Antipsychotic Agents