Minocycline-induced hepatitis with autoimmune features and neutropenia.
Minocycline can cause various types of hepatotoxicity. We report an 18-year-old male who developed a delayed onset of minocycline-induced cholestatic hepatitis with autoimmune features and neutropenia. He responded to withdrawal of the drug and a short course of corticosteroids. If minocycline is to be administered, then periodic monitoring for hepatoxicity is recommended.
Department of Medicine, Christ Hospital and Medical Center, Oak Lawn, IL 60453, USA.
G
G
Bhat
J
J
Jordan
S
S
Sokalski
V
V
Bajaj
R
R
Marshall
C
C
Berkelhammer
D000152:Acne Vulgaris / Q000188:drug therapy; D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D019693:Hepatitis, Autoimmune / Q000209:etiology*; D006801:Humans; D008297:Male; D008911:Minocycline / Q000009:adverse effects* / Q000627:therapeutic use; D009503:Neutropenia / Q000209:etiology
D000900:Anti-Bacterial Agents; D008911:Minocycline