[Malignant mesodermal (Mullerian) mixed tumor of the ovary: histologic, immunohistochemical and cytologic study].
A rare case of aggressive ovarian tumor in a 38-year-old female is described. Cytological diagnosis of the intraoperative smears was difficult because of the presence of the epithelial and non-epithelial components. The latter consisted of two types: spindle cells and roundish undifferentiated cells with multinuclear forms. Histologically, it was a malignant mesodermal (Mullerian) mixed tumor. Round mesenchymal cells expressed desmin and vimentin while spindle cells expressed myoglobin. Non-epithelial component was verified as leiomyosarcoma and rhabdomyosarcoma. Cells of the epithelial component expressed cytokeratins and epithelial membrane antigen.
Research Institute of Clinical Oncology, Cancer Research Center, Moscow.
V D
VD
Ermilova
A V
AV
Smirnov
V K
VK
Sokolova
A M
AM
Kovrigina
S O
SO
Nikokgosian
D000328:Adult; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D007430:Intraoperative Care; D018200:Mixed Tumor, Mullerian / Q000737:chemistry / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000737:chemistry / Q000473:pathology*