Transient hypocalcemia with elevated serum parathormone in an infant of a hyperparathyroid mother.
An infant presented at the age of 80 days with a hypocalcemic fit. The mother was found to have asymptomatic parathyroid adenoma. The infant's intact parathyroid hormone was high in the absence of hypomagnesemia, renal failure or overt rickets, which are known causes of secondary end-organ refractoriness. The patient was treated with calcium and 1-alpha-hydroxyvitamin D for only 2 weeks, but has remained asymptomatic and normocalcemic on follow-up to--the age of 2 years. It is believed that this has not been previously described and it is speculated that end-organ refractoriness, though brief, can account for all the symptoms.
Ismail
E A
EA
Department of Paediatrics, Farwaniya Hospital, Kuwait.
al-Shammari
N
N
Nadi
H
H
D017668:Age of Onset; D004830:Epilepsy, Tonic-Clonic / Q000209:etiology; D005260:Female; D006801:Humans; D006961:Hyperparathyroidism / Q000150:complications*; D006996:Hypocalcemia / Q000209:etiology*; D007011:Hypoparathyroidism / Q000150:complications / Q000209:etiology*; D007223:Infant; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications