[Colonic Crohn's disease: results of treatment].
Sixty patients with Crohn's colitis were separated into 2 groups: A) without perianal lesions, 12 patients; B) with perianal lesions, 48 patients. The mean age at the beginning of symptomatology was 41.4 years in group A and 31.7 in B. The number of patients that underwent surgical treatment were similar in both groups. Fifty eight operations were performed in 29 patients, mean 0.33 operations/patient in group A and 2.16 in B. Ileal pouch anal anastomosis were performed in 5 patients, with loss of reservoir in one. There was no difference in need of hospitalization between the 2 groups. At mean follow-up of 8.9 years, 37 patients presented at least one extra-intestinal manifestation, 21 a perianal lesion, 39 were taking drugs and 31 were symptomatic. In the group of 31 patients that received only medical treatment, 24 (77.4%) are still on drugs and only 9 are assymptomatic. In the group of 29 patients that were operated on, 12 (41.4%) are taking drugs and 19 (65.5%) are assymptomatic. The difference concerning results of treatment between patients on medical treatment and operated were statistically significant. A permanent ileostomy was performed in 19(65.5%) patients. Two patients died during clinical treatment and one of postoperative complications.
Departamento de Gastroenterologia, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo.
M G
MG
Teixeira
A
A
Habr-Gama
C
C
Takiguti
J E
JE
Calache
M G
MG
Almeida
W G
WG
Teixeira
H W
HW
Pinotti
D000328:Adult; D003424:Crohn Disease / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011446:Prospective Studies; D011788:Quality of Life; D016896:Treatment Outcome