Two cases of chronic arthritis of the forearm due to Mycobacterium tuberculosis.
In the absence of coexisting active pulmonary disease, tuberculosis is frequently not considered in the differential diagnosis of chronic inflammation of the joints. The cases of two immigrant patients with tuberculous arthritis involving the forearm are reported. In both cases non-specific arthritis or trauma was suspected, resulting in a delay between the onset of symptoms and institution of specific therapy of 21 and 24 months, respectively. Diagnosis was achieved by histological and microbiological examination of synovial biopsy material. Polymerase chain reaction for Mycobacterium tuberculosis complex was positive in only one patient. Treatment consisted of antituberculosis chemotherapy, surgical synovectomy, and debridement of the affected joints. These cases serve as a reminder that, although rare, tuberculosis can cause chronic arthritis.
Institut für Medizinische Mikrobiologie, Zentrum der Hygiene, Johann-Wolfgang-Goethe Universität, Frankfurt/Main, Germany.
K P
KP
Hunfeld
M
M
Rittmeister
T A
TA
Wichelhaus
V
V
Brade
R
R
Enzensberger
D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D001170:Arthritis, Infectious / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy; D004359:Drug Therapy, Combination; D005260:Female; D005542:Forearm; D006801:Humans; D008297:Male; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D013582:Synovial Fluid / Q000382:microbiology; D016896:Treatment Outcome; D014394:Tuberculosis, Osteoarticular / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy
D000995:Antitubercular Agents