[Omeprazole: a new treatment for paranasal sinus polyps in Widal syndrome. Preliminary study].
A preliminary report is made of the potential therapeutic effect of omeprazol in reducing nasosinusal polyps. This study is based on the empirical observation of nasal airflow improvement in patients suffering from nasosinusal polyposis after administering omeprazol. Different phases of the study suggested that patients with Widal's syndrome benefited the most. Based on the results of this study, we have undertaken a randomized, parallel, double-blind, placebo-controlled clinical trial.
Servicio de ORL, Hospital General Universitario Vall d'Hebron, Barcelona.
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Serra
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Piñas
J A
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Arnaiz
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Quesada
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Naches
J
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Lorente
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Carne
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000627:therapeutic use*; D004311:Double-Blind Method; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008875:Middle Aged; D009298:Nasal Polyps / Q000188:drug therapy*; D009853:Omeprazole / Q000627:therapeutic use*; D011282:Pregnenediones / Q000627:therapeutic use; D013577:Syndrome
D000893:Anti-Inflammatory Agents; D000897:Anti-Ulcer Agents; D011282:Pregnenediones; D009853:Omeprazole; C021988:deflazacort