Transplantation of unrelated cord blood cells.
A 43-year-old woman with Philadelphia chromosome (Ph) positive chronic myelogenous leukemia in acute phase received high-dose chemotherapy followed by transfusion of 12 randomly selected units of umbilical cord blood. HLA analysis showed cells of one donor from day +10 to day +43 post-transfusion. This unit was HLA class II identical with that of the patient.
Weinreb
S
S
Department of Medicine, Baystate Medical Center, Springfield, MA 01199, USA.
Delgado
J C
JC
Clavijo
O P
OP
Yunis
E J
EJ
Bayer-Zwirello
L
L
Polansky
L
L
Deluhery
L
L
Cohn
G
G
Yao
J T
JT
Stec
T C
TC
Higby
D
D
Anderzejewski
C
C
D000328:Adult; D005260:Female; D005312:Fetal Blood / Q000166:cytology; D016332:Fetal Tissue Transplantation; D006085:Graft Survival; D018380:Hematopoietic Stem Cell Transplantation; D006650:Histocompatibility Testing; D006801:Humans; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000628:therapy*; D014184:Transplantation, Homologous