Motor neurone disease in South Estonia. Diagnosis and incidence rate.
The current study evaluated the diagnostic standards of MND and epidemiological markers of MND in Estonia. A total of 108 patients were referred to the University Hospital from 1986 to 1995 with the first suggested diagnosis or final diagnosis of amyotrophic syndrome, amyotrophic lateral sclerosis (ALS), progressive bulbar paralysis (PBP) or progressive muscular atrophy (PMA). In addition neurologists of the region and the National Society of Neuromuscular disorders were contacted. Some 94 patients satisfied the diagnostic criteria. The annual incidence rate in South Estonia and in the city of Tartu ranged from 0.5 to 2.8 per 100,000. The mean annual incidence rate in Tartu is 1.98 and in South Estonia in general 1.3. The highest incidence rate was 8.3 for men in the age group 60 to 64 years and 7.49 in the age group 70-74; among female patients the highest incidence rate -4.6 was in the age group from 65 to 69.
Gross-Paju
K
K
Tartu University Hospital, Department of Neurology, Estonia.
Oöpik
M
M
Lüüs
S M
SM
Kalbe
I
I
Puksa
L
L
Lepik
T
T
Kaasik
A E
AE
D000328:Adult; D000368:Aged; D000690:Amyotrophic Lateral Sclerosis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D001921:Brain / Q000473:pathology; D010244:Bulbar Palsy, Progressive / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D003430:Cross-Sectional Studies; D003906:Developing Countries; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D004957:Estonia / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D016472:Motor Neuron Disease / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology; D009134:Muscular Atrophy, Spinal / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D009460:Neurologic Examination; D011785:Quality Assurance, Health Care