Oocyte donation: does a previous attempt affect a subsequent attempt?
OBJECTIVE
To analyze the effect of a previous donor oocyte cycle on the outcome of subsequent attempts.


METHODS
Retrospective study.


METHODS
Oocyte donation program at The New York Hospital/Cornell Medical Center.


METHODS
Two hundred sixty-seven patients undergoing 354 fresh cycles of oocyte donation.


METHODS
None.


METHODS
Clinical outcomes were divided into groups based on the attempt number of each cycle for each patient. Results were calculated for each recipient cycle.


RESULTS
A clinical pregnancy rate of 56.2% and ongoing pregnancy/delivery rate per retrieval of 50.3% were noted. No statistically significant differences in clinical outcomes were found between the first, second, and third attempts. A significant increase was noted in the ongoing pregnancy/delivery rate per recipient cycle for the second attempt in those patients who had a delivery after the first attempt compared with those who did not.


CONCLUSIONS
We demonstrated an overall clinical pregnancy rate of 56.2% and an ongoing pregnancy/delivery rate of 50.3% per retrieval. Outcome for the second attempt was associated with success or failure during an initial attempt at oocyte donation.
Spandorfer
S D
SD
The Center for Reproductive Medicine and Infertility, Department of Obstetrics and Gynecology, The New York Hospital/Cornell Medical Center, New York 10021, USA.
Moomjy
M
M
Davis
O K
OK
Barmat
L I
LI
Cholst
I
I
Rosenwaks
Z
Z
D000328:Adult; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D008875:Middle Aged; D009865:Oocytes; D011247:Pregnancy; D011256:Pregnancy Outcome; D019233:Retreatment; D012189:Retrospective Studies; D014019:Tissue Donors