Biclonal primary plasma cell leukemia.
Authors present a multiparameter pathological study in a case of rapid biclonal primary plasma cell leukemia. The immunohistochemical data revealed aberrant phenotypes (monocyte, epithelial and T-cell) probably in connection with microenvironmental influences. Biclonality can be attributed to class switching during malignant transformation. Static image cytometry showed aneuploidy. The blasts of this process are active immunoregulatory cells.
Department of Pathology, County Hospital of Zala, Zalaegerszeg, Hungary.
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Tóth
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Sipos
D000328:Adult; D006801:Humans; D019044:Image Cytometry; D007952:Leukemia, Plasma Cell / Q000473:pathology* / Q000503:physiopathology; D008297:Male; D010950:Plasma Cells / Q000473:pathology*