[Effects of Hirudo therapy on lipid peroxidation and catalase activity of the rabbit retina after light-induced eye injuries].
Effect of Hirudo therapy on the level of lipid peroxidation (LPO) products and catalase activity in the retina and pigmented epithelium (PE) after exposure to intensive illumination is assessed. Light injury to the eye (100,000 lux in 90 min) leads to accumulation of LPO products and suppression of catalase activity. Hirudo therapy after potent light exposure of the eye decreased the level of hydroperoxide and malonic dialdehyde and normalized retinal and PE catalase activity, thus exerting a therapeutic antioxidant effect. Hirudo therapy before illumination did not notably protect the eye as regards the content of LPO products and catalase activity.
Musaev Galbinur
P I
PI
Magomedov
N M
NM
Kulieva
S A
SA
Babaev
Kh F
KhF
D000818:Animals; D002374:Catalase / Q000378:metabolism*; D005131:Eye Injuries / Q000209:etiology / Q000378:metabolism / Q000628:therapy*; D007865:Leeches; D008027:Light / Q000009:adverse effects*; D015227:Lipid Peroxidation; D008315:Malondialdehyde / Q000378:metabolism; D010857:Pigment Epithelium of Eye / Q000201:enzymology / Q000378:metabolism; D011817:Rabbits; D012160:Retina / Q000201:enzymology / Q000378:metabolism*
D008315:Malondialdehyde; D002374:Catalase