[A case of left main bronchus obstruction due to recurrent esophageal cancer successfully treated by Nd-YAG laser followed by radiotherapy, low-dose CDDP and continuous infusion of 5-FU].
A 63-year-old female patient with obstruction of left main bronchus due to recurrent esophageal cancer was treated by emergency Nd-YAG laser therapy under bronchoscopy. Severe dyspnea subsided dramatically and she was the given radiotherapy with a total dose of 50 Gy (2 Gy/f and 25 f/5 wks). Concurrent chemotherapy was performed at the 3rd week of radiation therapy. In this chemotherapy of CDDP plus 5-FU, CDDP (10 mg/day) was given for 5 days by intravenous and 5-FU (500 mg/day) for 5 days by continuous infusion the same week. By this treatment, a partial response (PR) was obtained, and the patient returned to normal life. But after 4 months, she had a recurrent lesion at the same place, and underwent only palliative laser therapy. Nd-YAG laser therapy for obstructive lesion of trachea due to recurrent cancer is the most useful one, but some subsequent treatment is required.
First Dept. of Surgery, Nagasaki University School of Medicine.
S
S
Hara
N
N
Itoyanagi
C
C
Ryu
H
H
Fukuoka
H
H
Ayabe
H
H
Nakao
T
T
Nogawa
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001982:Bronchial Diseases / Q000532:radiotherapy*; D001984:Bronchial Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000532:radiotherapy*; D002294:Carcinoma, Squamous Cell / Q000556:secondary* / Q000628:therapy; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D003251:Constriction, Pathologic; D004938:Esophageal Neoplasms / Q000473:pathology* / Q000628:therapy; D005260:Female; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D053685:Laser Therapy; D008875:Middle Aged; D009360:Neoplastic Cells, Circulating
D002945:Cisplatin; D005472:Fluorouracil