Verapamil prevents cyclosporine-induced hypertension by modulating endothelin A receptor expression in rat kidney membranes.
Department of Neuroscience (Pharmacology Section), University of Pisa, Italy.
L
L
Giovannini
M
M
Migliori
D
D
Taccola
V
V
Panichi
B
B
Andreini
S
S
De Pietro
C
C
Filippi
S
S
Del Ry
M G
MG
Andreassi
M G
MG
Colombo
A
A
Biagini
D
D
Giannessi
R
R
Palla
D000818:Animals; D001794:Blood Pressure / Q000187:drug effects; D002462:Cell Membrane / Q000378:metabolism; D016572:Cyclosporine / Q000633:toxicity*; D019332:Endothelin-1 / Q000378:metabolism; D005786:Gene Expression Regulation / Q000187:drug effects; D006973:Hypertension / Q000139:chemically induced* / Q000517:prevention & control*; D007457:Iodine Radioisotopes; D007668:Kidney / Q000187:drug effects* / Q000378:metabolism; D008297:Male; D011869:Radioligand Assay; D051381:Rats; D017208:Rats, Wistar; D044022:Receptor, Endothelin A; D017466:Receptors, Endothelin / Q000096:biosynthesis* / Q000235:genetics; D014700:Verapamil / Q000494:pharmacology*
D019332:Endothelin-1; D007457:Iodine Radioisotopes; D044022:Receptor, Endothelin A; D017466:Receptors, Endothelin; D016572:Cyclosporine; D014700:Verapamil