Long-term results of intratumorous bleomycin-A5 injection for head and neck lymphangioma.
From June 1987 to June 1995, 200 patients with various types of head and neck lymphangioma were treated by intratumorous injection of bleomycin-A5. All 200 cases were followed from 2 to 10 years; 95 cases were followed for more than 5 years. The effective rate was 97%, and the curative rate was 86.5%. No pulmofibrosis or other serious complications were found. The relationships between the curative effect and tumor type, size, and side effect of bleomycin are discussed.
Department of Head and Neck, Cancer Hospital of Shandong, Linyi, China.
P Q
PQ
Zhong
F X
FX
Zhi
R
R
Li
J L
JL
Xue
G Y
GY
Shu
D000293:Adolescent; D000328:Adult; D000855:Anorexia / Q000139:chemically induced; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005334:Fever / Q000139:chemically induced; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015552:Injections, Intralesional; D008137:Longitudinal Studies; D008202:Lymphangioma / Q000188:drug therapy* / Q000473:pathology; D018191:Lymphangioma, Cystic / Q000188:drug therapy / Q000473:pathology; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D011658:Pulmonary Fibrosis / Q000517:prevention & control; D012074:Remission Induction
D000903:Antibiotics, Antineoplastic; D001761:Bleomycin