[A case of ill-defined vitiliginous lesions in the posterior polar regions of both eyes].
In a 34-year-old man, who was examined for binocular visual disturbance as chief complaint at the department of ophthalmology, we found ill-defined vitiliginous lesions of a size about 1/5 approximately 1/7 the diameter of the papilla in the fundal posterior polar regions of both eyes. Fluorescein angiography (FA) revealed hyperfluorescence of the vitiligo. Blood tests showed increased herpes simplex and herpes zoster varicellosus antibody titers and positive antinuclear antibodies (spekled type). Following steroid treatment, the vitiligo remitted, but reappeared later. Indocyanine green infrared fluorescein angiography (IA) revealed hyperfluorescence of the vitiligo. Fundus findings suggested multiple evanescent white dot syndrome (MEWDS), but were judged to be negative because 1. the vitiliginous lesions were morphologically different; 2. the onset site of the vitiligo was more posterior and polar-sided, 3. onset of the vitiligo was binocular, 4. the vitiligo recurred and 5. late hypofluorescence was not observed in IA.
Abe
S
S
Department of Ophthalmology, Iwaki Kyoritsu General Hospital, Japan.
Nishikatsu
H
H
Yasui
T
T
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D004396:Coloring Agents; D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green; D008297:Male; D008775:Methylprednisolone / Q000008:administration & dosage; D014820:Vitiligo / Q000175:diagnosis* / Q000188:drug therapy
D000893:Anti-Inflammatory Agents; D004396:Coloring Agents; D007208:Indocyanine Green; D008775:Methylprednisolone