P300 amplitude and antidepressant response to Sudarshan Kriya Yoga (SKY).
BACKGROUND
There is evidence that Sudarshan Kriya Yoga (SKY) has significant antidepressant effects.


OBJECTIVE
The present study examined whether pretreatment P300 ERP amplitude predicts antidepressant response to SKY.


METHODS
Consenting, drug-free depressed patients (n = 30; dysthymics, 15, melancholics, 15) who received SKY as the sole treatment were assessed clinically at pretreatment, 1 month and 3 months. Auditory P300 was recorded before treatment.


RESULTS
Twenty-two patients responded favourably to SKY. The pretreatment P300 amplitude neither distinguished responders and non-responders nor was associated with differential rates of response.


CONCLUSIONS
It is concluded that SKY therapy is uniformly effective regardless of the pretreatment P300 amplitude.
Naga Venkatesha Murthy
P J
PJ
Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, India.
Janakiramaiah
N
N
Gangadhar
B N
BN
Subbakrishna
D K
DK
D000328:Adult; D003866:Depressive Disorder / Q000503:physiopathology / Q000628:therapy*; D018913:Event-Related Potentials, P300; D005260:Female; D006801:Humans; D008297:Male; D015013:Yoga