[The effect in vitro of permanent and variable magnetic fields on immunocompetent blood cells from patients with hemoblastoses and non-Hodgkin's malignant lymphoma].
Immunologic parameters were studied in 54 patients with myeloma multiplex (MM), acute leukosis (AL), non-Hodgkin's disease (NHD) before and after in vitro exposure of these patients' blood to weak constant magnetic field (CMF) and CMF in combination with variable magnetic field (VMF). Blood irradiation with CMF over 60 min in AL and MM patients brought about in some cases enhancement of the expression of +CD3, +CD4 and CD8 together with augmentation of the immunoregulatory index. At the same time phagocytic activity of leucocytes got increased as did digesting capability and index of completeness of phagocytosis, i.e. exposure to CMF prevents a blockade of receptors for neutrophilic complement, increases their phagocytic activity and antibody-dependent cellular cytotoxicity. In studying immunocompetent cells of NHD patients' blood, T-helpers were found out to be moderately decreased, with T-suppressors to a greater extent so. Study of CMF and VMF effects on MM and AL patients' blood has shown an immunocorrective action thereof though to a lesser extent so.
Bessmel'tsev
S S
SS
Abdulkadyrov
K M
KM
Lavrushina
T S
TS
Gonchar
V A
VA
Zamotina
T B
TB
D000208:Acute Disease; D015703:Antigens, CD / Q000276:immunology*; D016175:B-Lymphocyte Subsets / Q000276:immunology*; D016516:CD4-CD8 Ratio; D004864:Equipment and Supplies; D006801:Humans; D066298:In Vitro Techniques; D007938:Leukemia / Q000276:immunology / Q000628:therapy*; D008228:Lymphoma, Non-Hodgkin / Q000276:immunology / Q000628:therapy*; D008280:Magnetics / Q000627:therapeutic use*; D009101:Multiple Myeloma / Q000276:immunology / Q000628:therapy*; D010587:Phagocytosis; D016176:T-Lymphocyte Subsets / Q000276:immunology*
D015703:Antigens, CD