Endothelial study of iris-claw phakic lens: four year follow-up.
OBJECTIVE
To study quantitative and morphometric endothelial changes in phakic eyes implanted with the Worst iris-claw lens to correct high myopia.


METHODS
Department of Ophthalmology, University Hospital "La Fe", Valencia, Spain.


METHODS
This retrospective study involved 111 phakic eyes (73 patients) implanted with the Worst iris-claw lens. Noncontact specular microscopy and computer-assisted analysis was performed preoperatively and 6 months and 1, 2, 3, and 4 years postoperatively.


RESULTS
The mean cell loss was 3.85% at 6 months, 6.59% at 1 year, 9.22% at 2 years, 11.68% at 3 years, and 13.42% at 4 years. At 2 years, the hexagonality and coefficient variation in cell size were close to the preoperative levels. No major complications were seen; early postoperative corneal touch required intraocular lens (IOL) removal in 1 case (0.9%). Four eyes (3.6%) needed a reoperation because of poor IOL fixation (2 eyes), traumatic subluxation of the IOL (1 eye), and miscalculation of the IOL power (1 eye).


CONCLUSIONS
Although there was a slight progressive cell loss after IOL implantation, the morphometric changes recovered and were close to the preoperative levels. This suggests that endothelial damage occurred primarily during the surgical procedure.
Department of Ophthalmology, University Hospital La Fe, University of Valencia, Spain.
J L
JL
Menezo
A L
AL
Cisneros
V
V
Rodriguez-Salvador
D000328:Adult; D000867:Anterior Chamber / Q000601:surgery*; D002452:Cell Count; D048429:Cell Size; D003316:Corneal Diseases / Q000209:etiology / Q000473:pathology; D004728:Endothelium, Corneal / Q000473:pathology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007498:Iris / Q000601:surgery; D019654:Lens Implantation, Intraocular / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000601:surgery*; D011183:Postoperative Complications; D012086:Reoperation; D012189:Retrospective Studies; D014792:Visual Acuity