Primary cutaneous T-cell lymphoma involving the cheek: an infant case with a unique clinicopathologic feature.
We report a clinicopathologic feature of primary cutaneous T-cell lymphoma (CTCL) in a five-year-old boy with increasing swelling of his cheek since two years of age. Histologically, an infiltrate of atypical lymphoid cells with mature T-cell phenotype and clonality was prominent from the dermis to the subcutaneous tissue of the cheek. Although little effect was seen with aggressive multidrug-combined chemotherapy, therapy with interferon-alpha and steroids achieved a prolonged remission. This patient may provide important clues to understanding the clinicopathologic feature of rare primary CTCL in young children.
Imaizumi
M
M
Department of Pediatrics, Tohoku University School of Medicine, Sendai, Japan. mimaizumi@ped.med.tohoku.ac.jp
Ichinohasama
R
R
Sato
A
A
Mikami
H
H
Abukawa
D
D
Asanuma
A
A
Aikawa
J I
JI
Tanida
M
M
Nakagawa
H
H
Iinuma
K
K
D002610:Cheek / Q000473:pathology*; D002675:Child, Preschool; D015321:Gene Rearrangement; D006801:Humans; D016130:Immunophenotyping; D016410:Lymphoma, T-Cell, Cutaneous / Q000188:drug therapy / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology*