The potential role of interleukin-1 in the ovulatory process: an evolving hypothesis.
Despite the apparent preliminary nature of the observations cited herein, there is every reason to believe that continued investigation will provide new and meaningful insight relevant to the understanding of the complex interactions between the various cellular components of the ovary. If recent progress is any indication, the next decade may reveal that intraovarian cytokine messengers, as well as a host of growth factors, have major roles throughout the ovarian life cycle.
Adashi
E Y
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Department of Obstetrics and Gynecology, University of Utah Health Services Center, Salt Lake City 84108, USA. eadashi@hsc.utah.edu
D000818:Animals; D005260:Female; D006801:Humans; D053590:Interleukin 1 Receptor Antagonist Protein; D007375:Interleukin-1 / Q000037:antagonists & inhibitors / Q000235:genetics / Q000502:physiology*; D010053:Ovary / Q000166:cytology / Q000502:physiology*; D010060:Ovulation / Q000502:physiology*; D011453:Prostaglandins / Q000096:biosynthesis; D012795:Sialoglycoproteins / Q000502:physiology; D015398:Signal Transduction
C507763:IL1RN protein, human; D053590:Interleukin 1 Receptor Antagonist Protein; D007375:Interleukin-1; D011453:Prostaglandins; D012795:Sialoglycoproteins