Differential approach to psychosurgery of obsessive disorders.
One of the most frequent indications of psychosurgical treatment is incurable obsessions. Up to now, capsulotomy or cingulotomy has been preferred. In our opinion, the variety of obsessive conditions require a more thorough approach to the selection of interbrain targets. Forty-seven patients with pure obsessive-compulsive disorders as well as disorders connected with depressions, epileptic syndrome, schizophreniform state and Gilles de la Tourette's syndrome with extremely severe resistance to medical therapy were examined. Eighteen patients were operated on. Surgical treatment is permissible only in cases fulfilling the three following criteria: (1) clinicopsychopathological permissibility (duration of disease, resistance to medication, psychopathological status); (2) physiological permissibility (the presence of a brain target, defining the psychopathological status), and (3) technical permissibility (the availability of proper stereotactic, imaging, electrophysiological and other apparatus necessary to carry out the surgical treatment). One supposes that the outcome of surgical treatment is determined by all three criteria. For the purpose of improving the efficiency of stereotactic treatment, a number of methods of surgical treatment depending on the psychopathological status are suggested. For example, in case of comorbidity of obsession with the epileptiform syndrome, we suggest cingulotomy (capsulotomy) and amygdalotomy; in case of comorbidity with depression we suggest cingulotomy and innominatotomy. The long-term observation of the outcome of stereotactic treatment covers a period from 2 up to 9 years.
Korzenev
A V
AV
Bechterev Psychoneurological Research Institute, Russian Academy of Sciences, Saint Petersburg, Russia.
Shoustin
V A
VA
Anichkov
A D
AD
Polonskiy
J Z
JZ
Nizkovolos
V B
VB
Oblyapin
A V
AV
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000601:surgery*; D003342:Corpus Striatum / Q000601:surgery; D003452:Cryosurgery; D005500:Follow-Up Studies; D006179:Gyrus Cinguli / Q000601:surgery; D006801:Humans; D008875:Middle Aged; D009771:Obsessive-Compulsive Disorder / Q000601:surgery*; D011612:Psychosurgery; D012720:Severity of Illness Index; D013238:Stereotaxic Techniques; D013787:Thalamic Nuclei / Q000601:surgery; D005879:Tourette Syndrome / Q000601:surgery*; D016896:Treatment Outcome