A comparison of prosthetic materials used to repair abdominal wall defects.
Large abdominal wall defects may require a prosthesis for closure. The aim of our study was to identify the best material for abdominoplasty in pediatric patients. One hundred twenty-eight Wistar KY strain male rats (3 weeks old) were used. All animals underwent celiotomy via a midline skin incision. They were divided into seven groups as follows: the animals in groups 1 through 6 underwent full-thickness abdominal wall excision 3 cm in diameter. The animals in group 1 underwent primary closure. In groups 2 through 6 the defect was closed with prosthetic material. In Group 7, a sham operation was performed. Daily weights were measured. The animals were killed after 3 and 9 weeks. Adhesion scores were assigned for each group. Vicryl mesh resulted in the fewest adhesions and had no effect on weight gain in the developing rats.
Mori
N
N
Second Department of Surgery, Yamanashi Medical University, Yamanashi, Japan.
Takano
K
K
Miyake
T
T
Nishio
T
T
Muto
S
S
Koshizuka
K
K
Nakagomi
H
H
Kubo
M
M
Tada
Y
Y
D000009:Abdominal Muscles / Q000002:abnormalities* / Q000601:surgery*; D000818:Animals; D001672:Biocompatible Materials; D008297:Male; D011093:Polyethylene Terephthalates; D011095:Polyethylenes; D011098:Polyglactin 910; D011126:Polypropylenes; D011138:Polytetrafluoroethylene; D051381:Rats; D011921:Rats, Inbred WKY; D013526:Surgical Mesh; D000267:Tissue Adhesions / Q000209:etiology; D015430:Weight Gain
D001672:Biocompatible Materials; C016674:Plastipore; D011093:Polyethylene Terephthalates; D011095:Polyethylenes; D011126:Polypropylenes; D011098:Polyglactin 910; D011138:Polytetrafluoroethylene