Binding of influenza and paramyxoviruses to Group B Streptococcus with the terminal sialyl-galactose linkage.
Using the virus-binding assay and scanning electron microscopy (SEM), influenza A and B type viruses and two paramyxoviruses, parainfluenza (Sendai) and mumps viruses, were found to bind to Group B Streptococcus (GBS), type Ia and II, with the terminal sialyl-galactose linkage, although some viruses detached during the sample processing for SEM, and mumps virus did not bind to GBSIa. Binding of viruses eluted from GBS at 37 degrees C depended on combination of virus and GBS. The biological significance of these findings is discussed.
Hosaka
Y
Y
Department of Virology and Immunology, Osaka University of Pharmaceutical Sciences, Japan.
Kuroda
K
K
Ikeura
A
A
Iwamoto
T
T
Suzuki
Y
Y
D016667:Bacterial Capsules / Q000737:chemistry / Q000378:metabolism; D006389:Hemagglutinins, Viral / Q000378:metabolism; D009980:Influenza A virus / Q000378:metabolism; D009981:Influenza B virus / Q000378:metabolism; D008855:Microscopy, Electron, Scanning; D009109:Mumps virus / Q000378:metabolism; D009439:Neuraminidase / Q000378:metabolism; D009975:Orthomyxoviridae / Q000378:metabolism*; D018098:Paramyxovirinae / Q000378:metabolism*; D011991:Receptors, Virus / Q000378:metabolism; D018108:Respirovirus / Q000378:metabolism; D012794:Sialic Acids / Q000737:chemistry* / Q000378:metabolism; D013292:Streptococcus agalactiae / Q000378:metabolism / Q000821:virology*
D006389:Hemagglutinins, Viral; D011991:Receptors, Virus; D012794:Sialic Acids; D009439:Neuraminidase