Oxidative stress and coronary artery disease.
Over the past 10 years, research into oxidative processes in the vascular wall has taken two parallel tracks that are beginning to merge. One of the tracks concerns the oxidation of lipids, and the other is the impact of oxidative reactions on nitric oxide biology. This update focuses on data implicating oxidative inactivation of nitric oxide in atherosclerosis and hypercholesterolemia.
Emory University School of Medicine, Department of Internal Medicine, Atlanta, GA 30322, USA. dharr02@emory.edu
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D001161:Arteriosclerosis / Q000503:physiopathology*; D003327:Coronary Disease / Q000503:physiopathology*; D006801:Humans; D006937:Hypercholesterolemia / Q000503:physiopathology*; D018384:Oxidative Stress