[A case report: endometrial carcinoma response to intraperitoneal and intraarterial chemotherapy].
Intraperitoneal and arterial neo-adjuvant chemotherapy were given to one patient with endometrial carcinoma (clear cell adenocarcinoma). She was diagnosed as an inoperable advanced carcinoma (stage IV B) associated with direct invasion of the urinary bladder and pleural effusion. Intraperitoneal infusion therapy with CDDP 100 mg was given every 3 weeks. The patient was also given intra-uterine arterial infusion chemotherapy three times with CDDP and ADM. MRI, CT, and Cystoscopic examinations failed to detect any carcinoma. An optimal operation was performed. In a histological study, the uterine carcinoma was in complete remission. But a degenerative adenocarcinoma was shown at peritoneal dissemination.
Dept. of Obstetrics and Gynecology, Mito Red Cross Hospital.
T
T
Itagaki
Y
Y
Furusawa
Y
Y
Sasaki
H
H
Kurihara
G
G
Mitsukawa
D018262:Adenocarcinoma, Clear Cell / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D017024:Chemotherapy, Adjuvant; D002945:Cisplatin / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage; D004334:Drug Administration Schedule; D016889:Endometrial Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D007044:Hysterectomy; D007261:Infusions, Intra-Arterial; D007263:Infusions, Parenteral; D009361:Neoplasm Invasiveness; D016066:Pleural Effusion, Malignant / Q000473:pathology; D012074:Remission Induction; D001749:Urinary Bladder Neoplasms / Q000473:pathology
D004317:Doxorubicin; D002945:Cisplatin