Butyl-2-cyanoacrylate fixation of mandibular osteotomies.
Butyl-2-cyanoacrylate is an easily applied, bioresorbable, noninfective glue that may provide an alternative to conventional craniofacial fixation techniques. Recent studies have demonstrated that the healing and strength of glue fixation of bone fragments in the craniofacial skeleton is equivalent to that of plate and screw fixation. We sought to determine if this glue could also provide strength and healing in a more stressed environment, that of the mandible. Fourteen New Zealand White rabbits underwent mandibular osteotomies at the angle. The osteotomy was fixed with either a microplate (n = 4) or glue (n = 10). Mandibles were assessed 10 weeks postoperatively and classified according to bone healing, condylar morphology, and dental morphology. Callus and nonunion were more prevalent in the glued group, whereas condylar resorption was similar in both experimental groups. Despite the poor bony healing in the glued group, the teeth did not decay but modified their standard form to meet the demands of the anatomic deformity. Butyl-2-cyanoacrylate does not offer the biomechanical stability afforded by plates and screws in bone subject to large forces.
Division of Plastic and Reconstructive Surgery, Johns Hopkins Hospital, Baltimore, MD, USA.
M A
MA
Shermak
L
L
Wong
N
N
Inoue
E Y
EY
Chao
P N
PN
Manson
D000818:Animals; D001696:Biomechanical Phenomena; D001843:Bone Cements / Q000494:pharmacology*; D001860:Bone Plates; D001862:Bone Resorption / Q000473:pathology; D001863:Bone Screws; D004659:Enbucrilate / Q000494:pharmacology*; D005260:Female; D008334:Mandible / Q000473:pathology / Q000601:surgery*; D008422:Materials Testing; D010027:Osteotomy / Q000379:methods*; D011183:Postoperative Complications / Q000473:pathology; D011817:Rabbits; D013718:Tensile Strength; D014945:Wound Healing / Q000187:drug effects*
D001843:Bone Cements; D004659:Enbucrilate