Flow cytometry detection of intracytoplasmic cytokines after Neoral or sirolimus intake is an informative tool for monitoring in vivo immunosuppressive efficacy in renal transplant recipients.
Immunology Department, Rangueil University Hospital, Toulouse, France.
J
J
Tkaczuk
L
L
Rostaing
O
O
Puyoo
C
C
Peres
M
M
Abbal
D
D
Durand
E
E
Ohayon
D002478:Cells, Cultured; D016572:Cyclosporine / Q000627:therapeutic use*; D016207:Cytokines / Q000096:biosynthesis*; D016903:Drug Monitoring; D005434:Flow Cytometry / Q000379:methods; D006801:Humans; D007165:Immunosuppression Therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D015759:Ionomycin / Q000494:pharmacology; D016030:Kidney Transplantation / Q000276:immunology*; D007700:Kinetics; D015166:Monitoring, Immunologic; D011090:Polyenes / Q000627:therapeutic use*; D012016:Reference Values; D020123:Sirolimus; D013755:Tetradecanoylphorbol Acetate / Q000494:pharmacology; D018417:Th1 Cells / Q000187:drug effects / Q000276:immunology*; D018418:Th2 Cells / Q000187:drug effects / Q000276:immunology*; D013997:Time Factors
D016207:Cytokines; D007166:Immunosuppressive Agents; D011090:Polyenes; D015759:Ionomycin; D016572:Cyclosporine; D013755:Tetradecanoylphorbol Acetate; D020123:Sirolimus