[A case of successful hypospadias repair without infection using recombinant human granulocyte-colony stimulating factor (rhG-CSF) for idiopathic neutropenia].
A boy aged 1 year 8 months, who was referred to our hospital because of hypospadias, was followed for 17 months under a diagnosis of idiopathic neutropenia. He was given recombinant human granulocyte colony-stimulating factor (rhG-CSF) at a dosage of 37.5 micrograms/day for 2 days preoperatively. His absolute neutrophil count in peripheral blood increased to more than 500/microliter, and hypospadias repair (free graft method) was performed. RhG-CSF was administered on the first, sixth, and eleventh days after the operation, and the postoperative course was uneventful. During pediatric surgery in patients with neutropenia, appropriate administration of rhG-CSF may be useful for preventing infection.
Department of Urology, Nagoya City University Medical School.
Y
Y
Kojima
Y
Y
Hayashi
Y
Y
Umemoto
T
T
Sakakura
S
S
Sasaki
K
K
Kohri
F
F
Kato
D016179:Granulocyte Colony-Stimulating Factor / Q000627:therapeutic use*; D006801:Humans; D007021:Hypospadias / Q000601:surgery*; D007223:Infant; D008297:Male; D009503:Neutropenia / Q000628:therapy*; D011183:Postoperative Complications / Q000517:prevention & control*; D011994:Recombinant Proteins; D013521:Urologic Surgical Procedures, Male / Q000379:methods
D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor