A comparison of prosthetic materials used to repair abdominal wall defects.
Large abdominal wall defects may require a prosthesis for closure. The aim of our study was to identify the best material for abdominoplasty in pediatric patients. One hundred twenty-eight Wistar KY strain male rats (3 weeks old) were used. All animals underwent celiotomy via a midline skin incision. They were divided into seven groups as follows: the animals in groups 1 through 6 underwent full-thickness abdominal wall excision 3 cm in diameter. The animals in group 1 underwent primary closure. In groups 2 through 6 the defect was closed with prosthetic material. In Group 7, a sham operation was performed. Daily weights were measured. The animals were killed after 3 and 9 weeks. Adhesion scores were assigned for each group. Vicryl mesh resulted in the fewest adhesions and had no effect on weight gain in the developing rats.
Second Department of Surgery, Yamanashi Medical University, Yamanashi, Japan.
N
N
Mori
K
K
Takano
T
T
Miyake
T
T
Nishio
S
S
Muto
K
K
Koshizuka
H
H
Nakagomi
M
M
Kubo
Y
Y
Tada
D000009:Abdominal Muscles / Q000002:abnormalities* / Q000601:surgery*; D000818:Animals; D001672:Biocompatible Materials; D008297:Male; D011093:Polyethylene Terephthalates; D011095:Polyethylenes; D011098:Polyglactin 910; D011126:Polypropylenes; D011138:Polytetrafluoroethylene; D051381:Rats; D011921:Rats, Inbred WKY; D013526:Surgical Mesh; D000267:Tissue Adhesions / Q000209:etiology; D015430:Weight Gain
D001672:Biocompatible Materials; C016674:Plastipore; D011093:Polyethylene Terephthalates; D011095:Polyethylenes; D011126:Polypropylenes; D011098:Polyglactin 910; D011138:Polytetrafluoroethylene