[The separation of 10-alkyl derivatives and the hydrolysis products of 10-acyl derivatives of phenothiazine by an extraction method].
Hydrophobic characteristics of phenothiasine 10-acyl derivatives obtained by alkaline hydrolysis of native compounds permit their separation from native phenothiasine 10-alkyl derivatives during re-extraction from organic phase by 0.5 N solution of sulfuric acid. Separation of the two main groups of phenothiasine derivatives during the re-extraction phase improves the specificity of their further detection by thin-layer chromatography, spectrophotometry, and staining reactions.
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Egorov
D014150:Antipsychotic Agents / Q000032:analysis / Q000302:isolation & purification*; D006863:Hydrogen-Ion Concentration; D006868:Hydrolysis; D008722:Methods; D010640:Phenothiazines; D012996:Solutions
D014150:Antipsychotic Agents; D010640:Phenothiazines; D012996:Solutions