Comparative efficacy of pyrethrum marc with albendazole against sheep gastrointestinal nematodes.
The efficacies of pyrethrum marc and of albendazole against experimental sheep gastrointestinal nematode infection were compared. Sheep was infected orally with 10,000 larvae (Haemonchus spp. (60.1%), Oesophagostomum spp. (13.9%), Trichostrongylus spp. (13.2%), Cooperia spp. (8.3%), Nematodirus spp. (3.5%), Strongyloides spp. (0.8%) and Ostertagia spp. (0.2%). Faecal egg count reduction in albendazole-treated sheep was 100% by day 4 following treatment, compared to 37.03%, 31.3%, 38.9% and 51.8% on days 4, 6, 8 and 10 in pyrethrum mare-treated sheep. These reductions were statistically significant on days 8 and 10 post-treatment (p < 0.05). The potential for using pyrethrins for helminth treatment is discussed.
University of Nairobi, Faculty of Veterinary Medicine, Department of Public Health, Pharmacology and Toxicology, Kenya.
J M
JM
Mbaria
T E
TE
Maitho
E S
ES
Mitema
D J
DJ
Muchiri
D015766:Albendazole / Q000627:therapeutic use*; D000818:Animals; D000871:Anthelmintics / Q000627:therapeutic use*; D011723:Chrysanthemum cinerariifolium / Q000627:therapeutic use*; D018592:Cross-Over Studies; D005243:Feces / Q000469:parasitology; D005260:Female; D007411:Intestinal Diseases, Parasitic / Q000188:drug therapy / Q000662:veterinary*; D008297:Male; D009349:Nematode Infections / Q000188:drug therapy / Q000662:veterinary*; D010270:Parasite Egg Count / Q000662:veterinary; D008517:Phytotherapy; D010936:Plant Extracts / Q000627:therapeutic use; D012756:Sheep; D012757:Sheep Diseases / Q000188:drug therapy*
D000871:Anthelmintics; D010936:Plant Extracts; D015766:Albendazole