Inflammatory leiomyosarcoma may be characterized by specific near-haploid chromosome changes.
Identical near-haploid karyotypes with 28, X, +5, +18, +20, +21, +22 were found in two cases of inflammatory leiomyosarcoma, one of which had been reported previously as malignant fibrous histiocytoma. This abnormality may identify these tumours as a separate entity within this group of sarcomas.
Dal Cin
P
P
Centre for Human Genetics, University of Leuven, Belgium.
Sciot
R
R
Fletcher
C D
CD
Samson
I
I
De Vos
R
R
Mandahl
N
N
Willén
H
H
Larsson
O
O
Van den Berghe
H
H
D000328:Adult; D003937:Diagnosis, Differential; D006238:Haploidy; D018219:Histiocytoma, Benign Fibrous / Q000175:diagnosis / Q000235:genetics; D006801:Humans; D007621:Karyotyping; D007890:Leiomyosarcoma / Q000175:diagnosis / Q000235:genetics* / Q000648:ultrastructure; D008297:Male; D012983:Soft Tissue Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000648:ultrastructure