[Classification of cell-surface receptors based on molecular structures and functions].
The majority of cell-surface receptor proteins belong to one of three main families: ionotropic receptors, G protein-coupled receptors, and enzyme-containing receptors. Additionally, recent studies have revealed the existence of receptors which couple to nonreceptor protein tyrosine kinases. These receptors could be classified as a fourth family. In this review, we summarize structural and functional characteristics of each receptor family.
Department of Biophysical Genetics, Kanazawa University Graduate School of Medicine.
S
S
Yokoyama
H
H
Higashida
D000818:Animals; D019204:GTP-Binding Proteins / Q000378:metabolism; D006801:Humans; D007473:Ion Channels / Q000378:metabolism; D008024:Ligands; D011485:Protein Binding; D011505:Protein-Tyrosine Kinases / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000737:chemistry / Q000145:classification* / Q000502:physiology
D007473:Ion Channels; D008024:Ligands; D011956:Receptors, Cell Surface; D011505:Protein-Tyrosine Kinases; D019204:GTP-Binding Proteins