Multimodality magnetic resonance systems for studying free radicals in vivo.
The multimodality approach to in vivo detection of free radicals combines the relative benefits of three free radical detection modalities: conventional RF CW-ESR, LODESR and PEDRI. We have built apparatus capable of combining these modalities to allow sequential PEDRI and CW-ESR, sequential LODESR and proton NMR imaging and simultaneous LODESR and CW-ESR. These systems offer superior performance in terms of both the scope and quality of information over single-modality free radical detection systems.
Department of Biomedical Physics and Bioengineering, University of Aberdeen, Foresterhill, UK.
S J
SJ
McCallum
I
I
Nicholson
D J
DJ
Lurie
D000818:Animals; D055592:Biophysical Phenomena; D001703:Biophysics; D004578:Electron Spin Resonance Spectroscopy / Q000295:instrumentation / Q000379:methods*; D005609:Free Radicals / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy / Q000295:instrumentation / Q000379:methods*; D019047:Phantoms, Imaging; D011522:Protons
D005609:Free Radicals; D011522:Protons