[Activity of endogenous proteinases in glomerulonephritis in children].
Protease activities in serum and urine of 116 children with glomerulonephritis and 16 healthy children were tested using chromogenic peptide substrates Z-Dala_Leu-Arg-pNA and Glp-Ala-ALa-Leu-pNa. We found the dependence between activity of serine proteinases and clinical, morphological forms of primary glomerulonephritis and hypertension.
Department of Chemistry, Moscow State University, Moscow.
O V
OV
Chumakova
A V
AV
Kuznetsova
G N
GN
Rudenskaia
T V
TV
Sergeeva
V M
VM
Stepanov
T L
TL
Voiushina
T I
TI
Garankina
D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D002918:Chymotrypsin / Q000097:blood / Q000378:metabolism* / Q000652:urine; D005921:Glomerulonephritis / Q000097:blood / Q000150:complications / Q000201:enzymology*; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000201:enzymology; D013379:Substrate Specificity; D014357:Trypsin / Q000097:blood / Q000378:metabolism* / Q000652:urine
D002918:Chymotrypsin; D014357:Trypsin