Hydroxychloroquine myopathy.
A woman with systemic lupus erythematosus developed severe myopathy after a septicemic episode, and her treatment before admission was hydroxychloroquine sulfate and prednisolone. A muscle biopsy revealed no evidence of vasculitis and creatine kinase was normal. She continued taking maintenance prednisolone and with intensive physiotherapy her muscle strength slowly returned. It is possible that the hydroxychloroquine was responsible for the myopathy.
Richards
A J
AJ
Department of Rheumatology, Worthing Hospital, West Sussex, UK.
D000368:Aged; D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000009:adverse effects* / Q000627:therapeutic use; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000188:drug therapy; D017696:Myopathies, Nemaline / Q000139:chemically induced* / Q000473:pathology
D018501:Antirheumatic Agents; D006886:Hydroxychloroquine