Bone marrow transplantation for the treatment of alpha-mannosidosis.
We report successful bone marrow transplantation in a child with a severe form of alpha-mannosidosis, type I. There was complete resolution of the recurrent sinopulmonary disease and organomegaly, improvement in the bony disease, and stabilization of neurocognitive function.
Wall
D A
DA
Department of Pediatrics, St Louis University School of Medicine, Missouri, USA.
Grange
D K
DK
Goulding
P
P
Daines
M
M
Luisiri
A
A
Kotagal
S
S
D016026:Bone Marrow Transplantation; D001842:Bone and Bones / Q000000981:diagnostic imaging; D006801:Humans; D007223:Infant; D008297:Male; D011859:Radiography; D008363:alpha-Mannosidosis / Q000000981:diagnostic imaging / Q000628:therapy*