Computational analysis of bacterial sulfatases and their modifying enzymes.
The sequence analysis of enzymes that might modify bacterial sulfatases should be useful in the task of identifying the human sulfatase-modifying homologs--enzymes that are defective in the rare inherited disease multi-sulfatase deficiency.
Schirmer
A
A
Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, MA 02115, USA.
Kolter
R
R
D000595:Amino Acid Sequence; D001419:Bacteria / Q000201:enzymology*; D001665:Binding Sites; D019295:Computational Biology; D003545:Cysteine / Q000378:metabolism; D006801:Humans; D008969:Molecular Sequence Data; D012694:Serine / Q000378:metabolism; D013429:Sulfatases / Q000378:metabolism*
D012694:Serine; D013429:Sulfatases; D003545:Cysteine