Nuclear matrix of human ovarian cancer cells in vitro.
The epithelial neoplasia constitute 60% of all primary tumors of the ovary and 90% of these are malignant. Nuclear matrix has been found to be involved in normal and abnormal nuclear activities. Previously, we have identified tumor-associated nuclear matrix proteins in cancers of human liver, nasopharynx and cervix. In this study, we compared nuclear matrices of immortalized ovarian and cancer cell lines by morphometric and 2-D gel electrophoresis analysis.
Yang
L
L
Department of Anatomy, Chinese University of Hong Kong, China.
Yam
G H
GH
Fey
E G
EG
Cheng-Chew
S B
SB
Tsao
G S
GS
Wang
Z H
ZH
Chew
E C
EC
D015180:Electrophoresis, Gel, Two-Dimensional; D004591:Electrophoresis, Polyacrylamide Gel; D005260:Female; D006801:Humans; D007382:Intermediate Filaments / Q000473:pathology / Q000648:ultrastructure; D015530:Nuclear Matrix / Q000737:chemistry / Q000473:pathology* / Q000648:ultrastructure; D009687:Nuclear Proteins / Q000032:analysis*; D010051:Ovarian Neoplasms / Q000737:chemistry / Q000648:ultrastructure*; D014407:Tumor Cells, Cultured
D009687:Nuclear Proteins