Influence of sperm surface antibodies on spontaneous pregnancy rates.
OBJECTIVE
To determine the rates of spontaneous pregnancies among women whose infertile male partners had sperm surface antibodies.


METHODS
Retrospective analysis.


METHODS
Infertility clinic of a university referral center.


METHODS
One hundred fifty-seven infertile couples; the male partner had IgA and/or IgG sperm surface antibody concentrations of >10%.


METHODS
None.


METHODS
Spontaneous pregnancy rates (PRs) over 6 years.


RESULTS
Spontaneous PRs correlated negatively with antibody concentrations.


CONCLUSIONS
Although the chance of spontaneous pregnancy among women whose partners had sperm antibody concentrations of <50% was good, intracytoplasmic sperm injection should be recommended to patients with concentrations of >90%.
Abshagen
K
K
Institute of Reproductive Medicine, University of Münster, Germany.
Behre
H M
HM
Cooper
T G
TG
Nieschlag
E
E
D005260:Female; D006801:Humans; D007248:Infertility, Male / Q000276:immunology*; D008297:Male; D011247:Pregnancy; D018873:Pregnancy Rate; D011947:Receptors, Antigen, B-Cell / Q000276:immunology*; D012189:Retrospective Studies; D013094:Spermatozoa / Q000276:immunology*
D011947:Receptors, Antigen, B-Cell