Complex partial seizures and aphasia as initial manifestations of non-ketotic hyperglycemia. Case report.
We describe a case of non-ketotic hyperglycemia (NKH), heralded by complex partial seizures and aphasia of epileptic origin, besides versive and partial motor seizures. This clinical picture was accompanied by left fronto-temporal spikes in the EEG. The seizures were controlled by carbamazepine only after the control of the diabetes. A month later, carbamazepine was discontinued. The patient remained without seizures, with normal language, using only glybenclamide. Complex partial seizures, opposed to simple partial seizures, are rarely described in association to NKH. Epileptic activity localized over language regions can manifest as aphasia.
Batista
M S
MS
Escola Paulista de Medicina (EPM)/Universidade Federal de São Paulo (UNIFESP), Brasil.
Silva
D F
DF
Ferraz
H B
HB
de Andrade
L A
LA
D000927:Anticonvulsants / Q000627:therapeutic use; D001037:Aphasia / Q000209:etiology*; D002220:Carbamazepine / Q000627:therapeutic use; D017029:Epilepsy, Complex Partial / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D005905:Glyburide / Q000627:therapeutic use; D006801:Humans; D006944:Hyperglycemic Hyperosmolar Nonketotic Coma / Q000150:complications* / Q000175:diagnosis* / Q000188:drug therapy; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D008875:Middle Aged
D000927:Anticonvulsants; D007004:Hypoglycemic Agents; D002220:Carbamazepine; D005905:Glyburide