A population-based study on the prevalence of Hodgkin's disease in the region of Plovdiv.
The authors present the results of a ten-year cross sectional population-based epidemiologic study on the incidence-specific patterns of Hodgkin's disease. During the period 1986-1995 there were 259 new cases diagnosed with Hodgkin's disease in Plovdiv region which accounts for 26 new cases per year (range 16 to 37). There was a strong tendency towards steady increase in the HD incidence-specific rate with a median increase of 0.13 cases per year, rising from 1.05 in 1986 to 2.18 per 100.000 in 1995. The HD morbidity-specific incidence rate also increased with 1.07 new cases per year, rising from 12.41 to 21.80 cases per 100.000 in ten years. The age-specific incidence pattern shows a bimodal distribution, with the first peak occurring between the ages of 20 and 29, and the second--between 60 and 79 years of age and with a nadir of morbidity between 40 and 49 years of age. There is a strong male predominance with a male:female ratio of 1.3:1. The most common pathohistologic pattern was the nodular sclerosis type (56.75), followed by the mixed cellularity (32.05%), the lymphocyte predominance (6.18%) and the lymphocyte depletion patterns (5.02%).
Karnolski
I
I
Clinic of Hematology, Higher Medical Institute, Plovdiv, Bulgaria.
Ananoshtev
N
N
Nikolov
I
I
D000293:Adolescent; D000328:Adult; D000368:Aged; D002031:Bulgaria / Q000453:epidemiology; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006689:Hodgkin Disease / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012189:Retrospective Studies