Primary cutaneous T-cell lymphoma involving the cheek: an infant case with a unique clinicopathologic feature.
We report a clinicopathologic feature of primary cutaneous T-cell lymphoma (CTCL) in a five-year-old boy with increasing swelling of his cheek since two years of age. Histologically, an infiltrate of atypical lymphoid cells with mature T-cell phenotype and clonality was prominent from the dermis to the subcutaneous tissue of the cheek. Although little effect was seen with aggressive multidrug-combined chemotherapy, therapy with interferon-alpha and steroids achieved a prolonged remission. This patient may provide important clues to understanding the clinicopathologic feature of rare primary CTCL in young children.
Department of Pediatrics, Tohoku University School of Medicine, Sendai, Japan. mimaizumi@ped.med.tohoku.ac.jp
M
M
Imaizumi
R
R
Ichinohasama
A
A
Sato
H
H
Mikami
D
D
Abukawa
A
A
Asanuma
J I
JI
Aikawa
M
M
Tanida
H
H
Nakagawa
K
K
Iinuma
D002610:Cheek / Q000473:pathology*; D002675:Child, Preschool; D015321:Gene Rearrangement; D006801:Humans; D016130:Immunophenotyping; D016410:Lymphoma, T-Cell, Cutaneous / Q000188:drug therapy / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology*