Amplification of ABC transporter gene pgpA and of other heavy metal resistance genes in Leishmania tarentolae and their study by gene transfection and gene disruption.
Department of Microbiology, Université Laval, Québec, Canada.
M
M
Ouellette
A
A
Haimeur
K
K
Grondin
D
D
Légaré
B
B
Papadopoulou
D018528:ATP-Binding Cassette Transporters / Q000096:biosynthesis* / Q000235:genetics*; D000818:Animals; D018053:Arsenites / Q000494:pharmacology; D016054:DNA, Protozoan / Q000302:isolation & purification / Q000378:metabolism; D018432:Drug Resistance, Multiple / Q000235:genetics*; D005784:Gene Amplification; D017125:Genes, Protozoan; D007891:Leishmania / Q000187:drug effects / Q000235:genetics* / Q000502:physiology; D008562:Membrane Glycoproteins / Q000096:biosynthesis* / Q000235:genetics*; D019216:Metals, Heavy / Q000494:pharmacology*; D015800:Protozoan Proteins; D014162:Transfection / Q000379:methods
D018528:ATP-Binding Cassette Transporters; D018053:Arsenites; D016054:DNA, Protozoan; D008562:Membrane Glycoproteins; D019216:Metals, Heavy; C106891:PgpA protein, Leishmania; D015800:Protozoan Proteins; C015001:arsenite