Screening for the aneuploid fetus.
Advances in ultrasound technology have dramatically improved the detection of fetal defects. Although only an invasive test can provide a diagnosis, the incorporation of sonography into current biochemically based screening programs should significantly improve the detection of a host of other physically based fetal abnormalities. This article provides an overview and discussion of the prenatal sonographic features that may suggest the presence of a significant chromosomal abnormality.
Gross
S J
SJ
Department of Obstetrics & Gynecology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, New York, USA.
Bombard
A T
AT
D000782:Aneuploidy; D003937:Diagnosis, Differential; D004314:Down Syndrome / Q000000981:diagnostic imaging* / Q000196:embryology*; D005260:Female; D006801:Humans; D011247:Pregnancy; D012680:Sensitivity and Specificity; D016216:Ultrasonography, Prenatal / Q000379:methods