The Bactrocera tryoni homologue of the Drosophila melanogaster sex-determination gene doublesex.
A homologue of the bifunctional sex-determining gene, doublesex (dsx), has been identified in the tephritid fruit fly, Bactrocera tryoni, and has been found to be expressed in a sex-specific manner in adult flies. The male- and female-specific cDNAs are identical at their 5' ends but differ at their 3' ends and appear to be the products of alternate splicing. The level of identity of the sex-specific DSX proteins of B. tryoni with the D. melanogaster DSX proteins, across the region corresponding to the DNA binding domain and the oligomerization domains, is greater than 85%. Four sequence motifs which are ten to thirteen bases identical to the TRA/TRA-2 binding sites (thirteen-nucleotide repeat sequences) are present in the female-specific exon of the B. tryoni dsx gene.
Fruit Fly Research Centre, School of Biological Sciences, University of Sydney, New South Wales, Australia. dshearma@bio.usyd.edu.au
D C
DC
Shearman
M
M
Frommer
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D001665:Binding Sites; D015152:Blotting, Northern; D018076:DNA, Complementary; D004268:DNA-Binding Proteins / Q000235:genetics*; D004175:Diptera / Q000235:genetics*; D029721:Drosophila Proteins; D004331:Drosophila melanogaster / Q000235:genetics; D005091:Exons; D005260:Female; D019476:Insect Proteins / Q000235:genetics*; D008297:Male; D008969:Molecular Sequence Data; D012261:Ribonucleoproteins; D017386:Sequence Homology, Amino Acid; D019849:Sex Determination Processes
D018076:DNA, Complementary; D004268:DNA-Binding Proteins; C070369:DSX protein, Drosophila; D029721:Drosophila Proteins; D019476:Insect Proteins; D012261:Ribonucleoproteins; C066174:tra2 protein, Drosophila