[Decreased content of non-heme iron in the blood of patients with peripheral tapetoretinal abiotrophy].
Measurement of non-heme iron in the sera of patients with peripheral tapetoretinal abiotrophy aged 10-72 years with stages I-IV of the disease showed a statistically significant (26-30%) decrease of this parameter in comparison with healthy controls. Total iron-binding capacity of the serum was unchanged. The results are discussed with regard for previous reports about changed iron homeostasis in animals with hereditary retinal degeneration (Campbell rats) and the role of iron in the development and formation of nervous tissues.
Pozdeev
N V
NV
Volkova
M V
MV
Efimova
M G
MG
Astakhov
Iu S
IuS
Etingof
R N
RN
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D002648:Child; D006706:Homeostasis; D006801:Humans; D007501:Iron / Q000097:blood* / Q000378:metabolism; D008875:Middle Aged; D051381:Rats; D012174:Retinitis Pigmentosa / Q000097:blood*; D014792:Visual Acuity
D007501:Iron