[Morphologic criteria of the adaptation of the vascular bed of the myocardial ventricles in acute massive embolism of the pulmonary arteries in an experiment].
Acute massive pulmonary embolism was induced in 94 random-bred dogs. There were 3 groups of the time control (0, 1 and 6 hrs) and 4 experimental groups (1- and 6-hrs compensated, 1- and 6-hrs decompensated). Favorable signs of the vascular adaptation: moderate arterial plasmorrhagia; lack of blood stasis, heterogeneity of metabolic profiles of arteries; prevalence of anaerobic glycolysis; some prevalence of catabolic reactions over anabolic reactions. Non-favorable signs: considerable plasmorrhagia; perivascular edema; multiple stases and hemorrhages; venous thrombosis; a dramatic decrease of the enzymatic activity in the arterial wall.
State Medical University of Russian Federation, Moscow.
O D
OD
Mishnev
V V
VV
Karpova
D S
DS
Mel'chenko
M S
MS
Tverskaia
D000222:Adaptation, Physiological; D000818:Animals; D003326:Coronary Circulation / Q000502:physiology*; D003331:Coronary Vessels / Q000473:pathology*; D004285:Dogs; D005260:Female; D006352:Heart Ventricles / Q000473:pathology*; D008297:Male; D011655:Pulmonary Embolism / Q000473:pathology*