[Changes in small-angle light scattering by platelets during their activation and aggregation].
Small-angle light scattering (0.5-7 degrees) platelets is enhanced upon the adenosine-5'-diphosphate-induced formation of microaggregates of platelets. The intensity of the scattered light, measured within a short period of time after stimulation of platelets, may by used as a nephelometric quantitative index of their initial aggregation. The light transmittance of platelet suspensions decreases after stimulation due to both the rounding of cell body and the initial aggregation of cells. Sodium hypochlorite at concentrations corresponding to its content in tap water inhibits the Ca(2+)-induced aggregation of isolated rabbit platelets. The tap water causes the transition of platelets to a state that is refractory with respect to CaCl2.
Roshchupkin
D I
DI
Russian State Medical University, Moscow, Russia.
Berzhitskaia
V V
VV
Sokolov
A Iu
AIu
D000818:Animals; D001792:Blood Platelets / Q000737:chemistry* / Q000502:physiology; D008027:Light; D009391:Nephelometry and Turbidimetry; D010974:Platelet Aggregation; D011817:Rabbits; D051381:Rats; D012542:Scattering, Radiation