[Comparison of clinical and histological diagnosis in kidney post-transplantation period].
OBJECTIVE
To assess the agreement between clinical and histopathological diagnosis in a renal transplantation center, 40 episodes of acute renal failure were studied.


METHODS
Kidney biopsies were performed at the moment that a clinical diagnosis was made by the staff.


RESULTS
Nineteen episodes of acute tubular necrosis (ATN), eighteen episodes of acute cellular rejection (ACR), 2 humoral rejections and 1 acute cyclosporin nephrotoxicity episodes were diagnosed. ATN episodes were confirmed by renal biopsy in 84.21%, ACR episodes in 83.33%, humoral rejections in 100%. Renal biopsy showed ATN in the occurrence of clinical cyclosporin nephrotoxicity. Total agreement was 82.5%.


CONCLUSIONS
There is a good relationship between clinical and histopathological diagnosis in the post-transplantation period. Diagnostic mistakes occurred mainly when oliguria was present.
de Castro
M C
MC
Unidade de Transplante Renal, Faculdade de Medicina, Universidade de São Paulo.
Chocair
P R
PR
Saldanha
L B
LB
Nahas
W
W
Arap
S
S
Sabbaga
E
E
Ianhez
L E
LE
D001707:Biopsy, Needle; D016572:Cyclosporine / Q000627:therapeutic use; D006084:Graft Rejection / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000009:adverse effects* / Q000276:immunology; D007683:Kidney Tubular Necrosis, Acute / Q000473:pathology
D007166:Immunosuppressive Agents; D016572:Cyclosporine