[The effect of chemotherapeutic drugs on free-radical oxidation of lipids in the lymph of lung cancer patients].
Indices of lipid peroxidation in lymph from lung cancer patients before and after chemotherapy were studied. Chemotherapeutic drugs were shown to exert a moderate stressor effect on lymph by triggering oscillating reactions of endogenous antioxidant systems. Stress releases a pool of low-molecular weight antioxidants. Absence of catalase activity in plasma and lymphocytes is a peculiar feature of lymph in lung cancer patients.
Sidorenko
Iu S
IuS
Research Institute of Oncology, Rostov.
Frantsiiants
E M
EM
Tkacheva
E M
EM
Musienko
N V
NV
Kartashov
S Z
SZ
D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000494:pharmacology* / Q000627:therapeutic use; D005260:Female; D005609:Free Radicals; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects*; D008175:Lung Neoplasms / Q000188:drug therapy / Q000378:metabolism*; D008196:Lymph / Q000378:metabolism*; D008297:Male; D008875:Middle Aged
D005609:Free Radicals