[Anesthetic management of a patient with protein C deficiency associated with pulmonary thromboembolism].
A patient with protein C deficiency associated with massive pulmonary embolism underwent open heart tromboembolectomy. The operation was successfully performed under cardiopulmonary bypass using a usual dose of heparin 3 mg.kg-1. The effect of heparin was successfully reversed by the administration of protamine sulfate 6 mg.kg-1. Perioperative administration of fresh frozen plasma or protein C concentrates might be necessary to manage hypercoagulability in a patient with protein C deficiency.
Kogure
S
S
Anesthetic Division, Omori Red Cross Hospital, Tokyo.
Makita
K
K
Saitoh
Y
Y
Nakazawa
K
K
Amaha
K
K
D000328:Adult; D000758:Anesthesia / Q000379:methods*; D002315:Cardiopulmonary Bypass; D017128:Embolectomy; D006801:Humans; D008297:Male; D020151:Protein C Deficiency; D011655:Pulmonary Embolism / Q000209:etiology / Q000601:surgery*; D017131:Thrombectomy