[Tearing in a patient with glaucoma].
Lacrimal secretion analysis in glaucoma patients shows several changes depending on the kind of local treatment. The study shows: a. timolol induces: decreasing of the lacrimal secretion (Schirmer's test), decreasing of the basic lacrimal secretion (between 10-25%), the change of the stability and composition of the tears (tear film break-up time is reduced); b. pilocarpine induces: lacrimal puncta occlusion, increased lacrimal secretion, orbicular spasms and palpebral myoclonias. All this changes justify the careful follow-up of the glaucoma patients, specially of the patients of full age, in which normally appear a decrease of lacrimal secretions and of the patients using beta blockers, neuroleptics and other drugs with a known effect of decreasing lacrimal secretion.
Clinica Oftalmologie-Spitalul Universitar Bucureşti.
D P
DP
De Popa
G
G
Andreescu
C
C
Albu
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D000367:Age Factors; D000368:Aged; D002908:Chronic Disease; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010277:Parasympathomimetics / Q000627:therapeutic use; D010862:Pilocarpine / Q000627:therapeutic use; D012727:Sex Characteristics; D013666:Tears / Q000187:drug effects / Q000378:metabolism*; D013999:Timolol / Q000627:therapeutic use
D000319:Adrenergic beta-Antagonists; D010277:Parasympathomimetics; D010862:Pilocarpine; D013999:Timolol