Mania associated with codeine and paracetamol.
OBJECTIVE
We describe a patient in whom a manic episode was precipitated by use of panadeine forte, a preparation containing codeine and paracetamol.


METHODS
The patient developed a discrete manic psychotic episode.


METHODS
The treatment consisted of cessation of the Panadeine forte and antipsychotic medication.


RESULTS
The patient made a complete recovery after 1 week.


CONCLUSIONS
Mania can be induced by large doses of Panadeine forte, particularly if there is a biological predisposition.
Armadale Clinic, Perth, Australia.
K G
KG
Orr
J
J
Mostert
D J
DJ
Castle
D000082:Acetaminophen / Q000009:adverse effects*; D018712:Analgesics, Non-Narcotic / Q000009:adverse effects*; D000701:Analgesics, Opioid / Q000009:adverse effects*; D001714:Bipolar Disorder / Q000139:chemically induced*; D003061:Codeine / Q000009:adverse effects*; D004338:Drug Combinations; D006801:Humans; D017116:Low Back Pain / Q000188:drug therapy; D008297:Male; D008875:Middle Aged
D018712:Analgesics, Non-Narcotic; D000701:Analgesics, Opioid; D004338:Drug Combinations; D000082:Acetaminophen; D003061:Codeine