Production of nocardicyclins by clinical isolates of Nocardia pseudobrasiliensis and in vivo antitumor activity of the antibiotic.
Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Japan.
Y
Y
Tanaka
U
U
Gräefe
K
K
Yazawa
Y
Y
Mikami
D000818:Animals; D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic / Q000096:biosynthesis* / Q000494:pharmacology*; D002851:Chromatography, High Pressure Liquid; D004352:Drug Resistance, Microbial; D005285:Fermentation; D007942:Leukemia, Experimental / Q000188:drug therapy*; D051379:Mice; D009615:Nocardia / Q000145:classification / Q000302:isolation & purification / Q000378:metabolism*; D014407:Tumor Cells, Cultured / Q000378:metabolism
D018943:Anthracyclines; D000903:Antibiotics, Antineoplastic; C109702:nocardicyclin A; C109703:nocardicyclin B