Chronic rejection: increasing evidence for the importance of allogen-independent factors.
Chronic rejection is a process caused by an interplay of different risk factors. Early injury regardless of type, seems to be an important prognostic event. Later insults appear to contribute. As the individual components of the process are increasingly dissected and understood, means to modulate or normalize them will be forthcoming.
Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02150, USA.
M J
MJ
Wilhelm
M
M
Kusaka
J
J
Pratschke
N L
NL
Tilney
D000208:Acute Disease; D000917:Antibody Formation; D001926:Brain Death; D002908:Chronic Disease; D003586:Cytomegalovirus Infections / Q000276:immunology; D006084:Graft Rejection / Q000209:etiology* / Q000276:immunology / Q000473:pathology; D006650:Histocompatibility Testing; D006801:Humans; D007111:Immunity, Cellular; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D016030:Kidney Transplantation / Q000276:immunology* / Q000473:pathology; D009926:Organ Preservation; D011183:Postoperative Complications; D015427:Reperfusion Injury
D007166:Immunosuppressive Agents