Epithelioid leiomyosarcoma of the larynx.
BACKGROUND
Tumors of smooth muscle origin are rare in the upper aerodigestive tract, due to the paucity of smooth muscle in the area. A review of the literature revealed 34 reported cases of leiomyoma, 9 cases of leiomyosarcoma, and only 2 cases of epithelioid leiomyoma arising in the larynx.


METHODS
A case report of an epithelioid leiomyosarcoma arising in the right piriform fossa of a 38-year-old man is presented.


RESULTS
The tumor was treated with conservative surgical resection and postoperative radiotherapy. There was no evidence of locoregional recurrence 2 years postsurgery, and laryngeal function was preserved.


CONCLUSIONS
To our knowledge, this is the third case of a laryngeal epithelioid smooth muscle tumor to be reported in the world literature and the only documentation of an epithelioid leiomyosarcoma arising in the larynx.
Department of Otolaryngology, St. Joseph's Health Centre, University of Western Ontario, London, Canada.
R
R
Sindwani
T W
TW
Matthews
J
J
Thomas
V M
VM
Venkatesan
D000328:Adult; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D007822:Laryngeal Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D007825:Laryngectomy; D007890:Leiomyosarcoma / Q000175:diagnosis* / Q000556:secondary / Q000628:therapy*; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary; D008279:Magnetic Resonance Imaging; D008297:Male; D018714:Radiotherapy, Adjuvant; D014057:Tomography, X-Ray Computed