[A basic study of photodynamic therapy of experimental hepatoma with ME 2906].
We have studied effects of photodynamic diagnosis (PDD) and photodynamic therapy (PDT) in hepatoma as confirmed by the existence of hepatoma when using a new photosensitizer mono-L-aspartyl chlorin e6. Japanese white rabbits were selected to perform abdominal incision under intravenous anesthesia and transplant VX2 tumor cells into the liver left lobe for the hepatoma model. Hepatoma of 1 cm in diameter (at one week after transplantation) was used experimentally to radiate a semiconductor laser (664 nm, 200 J/cm2) for treatment.
Nakamura
J
J
3rd Dept. of Surgery, Toho University School of Medicine.
Kajiwara
H
H
Nakamura
M
M
Watanabe
M
M
Naganuma
K
K
Tanaka
H
H
Usui
S
S
Sumiyama
Y
Y
Saito
K
K
Aizawa
K
K
D000818:Animals; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D008114:Liver Neoplasms, Experimental / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D010778:Photochemotherapy; D017319:Photosensitizing Agents / Q000627:therapeutic use*; D011166:Porphyrins / Q000627:therapeutic use*; D011817:Rabbits
D000970:Antineoplastic Agents; D017319:Photosensitizing Agents; D011166:Porphyrins; C053434:Talaporfin