[Method of diagnosing liver tumors].
The investigation is concerned with developing a model for using blood serum from patients with hepatic tumors to induce the activity of a gamma-glutamyl transferase enzyme in homogenized bovine hepatic tissue culture. An immunoglobulin protein was found to be responsible for the effect. The technique under discussion (Patent No. 2027997) provides a means for differential diagnosis of hepatoma and liver metastasis, on the one hand, and cholecystitis, pancreatitis, hepatitis, echinococcosis and hemangioma of the liver, on the other. The effectiveness of the method was 94.7; sensitivity--90.8 and specificity--97.9%.
Frantsiiants
E M
EM
Research Institute of Oncology, Rostov.
Krylova
M N
MN
Strokun
E G
EG
Verkhovtseva
A I
AI
Kholodnyĭ
M D
MD
D000818:Animals; D002417:Cattle; D003937:Diagnosis, Differential; D004790:Enzyme Induction; D006801:Humans; D008099:Liver / Q000201:enzymology*; D008107:Liver Diseases / Q000097:blood / Q000175:diagnosis; D008113:Liver Neoplasms / Q000097:blood* / Q000175:diagnosis* / Q000201:enzymology / Q000556:secondary; D009924:Organ Culture Techniques; D012680:Sensitivity and Specificity; D005723:gamma-Glutamyltransferase / Q000378:metabolism*
D005723:gamma-Glutamyltransferase