[A case of report--interferon therapy is useful for chronic hepatitis C with human immunodeficiency virus infection].
A 42-year-old male type A hemophiliae who been using coagulates since 1971 was diagnosed Human Immunodeficiency Virus (HIV) positive in 1993. Medical history included liver disfunction in 1987, with chronic hepatitis C (CHC) diagnosed in 1989. He was admitted to the hospital in October, 1994 because of general fatigue. Serum transaminase was elevated, CD4 was 221/micro L, and CD8 was 990. CD4/CD8 ratio was 0.2. HCV was of genotype 2b and 10(6) copies/50 microL, 8 week-Interferon (IFN)-beta treatment was started. HCV RNA was eliminated by week 8 and was sustained for one year with no severe side effects. With careful patient screening, IFN therapy for CHC with HIV may be an effective treatment.
Yamashita
K
K
Department of General Medicine, Kyushu University Hospital.
Hayashi
J
J
Yamamoto
T
T
Pei
Y
Y
Ise
K
K
Kashiwagi
S
S
D000328:Adult; D015658:HIV Infections / Q000150:complications*; D006467:Hemophilia A / Q000150:complications; D019698:Hepatitis C, Chronic / Q000628:therapy*; D006801:Humans; D016899:Interferon-beta / Q000627:therapeutic use*; D008297:Male
D016899:Interferon-beta