Peptidomimetic growth hormone secretagogues. Design considerations and therapeutic potential.
Departments of Medicinal Chemistry, Clinical Pharmacology, Clinical Sciences, and Biochemistry and Physiology, Merck Research Laboratories, P.O. Box 2000, Rahway, New Jersey 07065, USA.
R P
RP
Nargund
A A
AA
Patchett
M A
MA
Bach
M G
MG
Murphy
R G
RG
Smith
D000595:Amino Acid Sequence; D000818:Animals; D015195:Drug Design; D013007:Growth Hormone-Releasing Hormone / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology / Q000502:physiology*; D006728:Hormones / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D019382:Human Growth Hormone / Q000378:metabolism* / Q000627:therapeutic use; D006801:Humans; D007030:Hypothalamo-Hypophyseal System / Q000502:physiology; D008969:Molecular Sequence Data; D009842:Oligopeptides / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology; D011487:Protein Conformation; D011986:Receptors, Somatotropin / Q000737:chemistry / Q000502:physiology*
D006728:Hormones; D009842:Oligopeptides; D011986:Receptors, Somatotropin; D019382:Human Growth Hormone; D013007:Growth Hormone-Releasing Hormone