The importance of systematic histological examination after loosening of an implant.
A 65-year-old man presented with a painful hip five years after a cemented replacement. Histological examination of a biopsy taken from tissue surrounding the femoral implant showed infiltration of a squamous-cell carcinoma. Further investigation revealed a primary growth in the left lung. This rare example of a metastasis in relation to a joint replacement illustrates the necessity for histological examination of the tissue adjacent to a loose prosthesis.
Allain
J
J
Service de Chirurgie Orthopédique, Hôpital Henri Mondor, Creteil, France.
Le Mouel
S
S
Voiçin
M C
MC
Delepine
G
G
Goutallier
D
D
D000368:Aged; D019644:Arthroplasty, Replacement, Hip; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000556:secondary*; D002484:Cementation; D005266:Femoral Neoplasms / Q000473:pathology / Q000556:secondary*; D005269:Femur / Q000473:pathology*; D006622:Hip Prosthesis; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology / Q000556:secondary; D008175:Lung Neoplasms / Q000473:pathology; D008207:Lymphatic Metastasis / Q000473:pathology; D008297:Male; D011475:Prosthesis Failure; D012086:Reoperation