Hypothesis: taste disorders in patients with liver disease may be mediated in the brain: potential mechanisms for a central phenomenon.
Patients with liver disease experience alterations in the sense of taste. There is increasing evidence to suggest that some of the symptoms associated with liver disease (e.g., pruritus) are mediated in the brain. A hypothesis for a brain-mediated mechanism underlying taste alterations in hepatic disorders is presented in this paper.
Division of Gastroenterology and Liver Disease, Beth Israel Medical Center, New York, New York 10003, USA.
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Bergasa
D000818:Animals; D001921:Brain / Q000503:physiopathology*; D006801:Humans; D008099:Liver / Q000294:innervation / Q000503:physiopathology; D008107:Liver Diseases / Q000150:complications* / Q000503:physiopathology; D013649:Taste / Q000502:physiology; D013651:Taste Disorders / Q000209:etiology* / Q000503:physiopathology