Bone marrow transplantation for the treatment of alpha-mannosidosis.
We report successful bone marrow transplantation in a child with a severe form of alpha-mannosidosis, type I. There was complete resolution of the recurrent sinopulmonary disease and organomegaly, improvement in the bony disease, and stabilization of neurocognitive function.
Department of Pediatrics, St Louis University School of Medicine, Missouri, USA.
D A
DA
Wall
D K
DK
Grange
P
P
Goulding
M
M
Daines
A
A
Luisiri
S
S
Kotagal
D016026:Bone Marrow Transplantation; D001842:Bone and Bones / Q000000981:diagnostic imaging; D006801:Humans; D007223:Infant; D008297:Male; D011859:Radiography; D008363:alpha-Mannosidosis / Q000000981:diagnostic imaging / Q000628:therapy*