Using fast sequential asymmetric fanbeam transmission CT for attenuation correction of cardiac SPECT imaging.
The objective of this study was to determine the feasibility of using a fast (short-duration) transmission computed tomogram (TCT), acquired immediately before or after the emission CT, to correct for photon attenuation in cardiac SPECT.


METHODS
The asymmetric fanbeam geometry with a 99mTc line source was used to acquire TCTs after conventional cardiac emission CT imaging on a triple-head SPECT system. The TCTs were reconstructed to generate patient-specific attenuation maps, which were used with an iterative maximum likelihood algorithm to reconstruct attenuation-corrected cardiac SPECT studies. The results of attenuation correction based on TCTs as short as 1 min were compared with long-duration transmission imaging for a phantom and several human studies.


RESULTS
Attenuation correction based on asymmetric fanbeam TCT significantly improves the uniformity of images of a uniform tracer distribution in a cardiac-thorax phantom configured to simulate a large patient. By using a high-activity line source and a rapid camera rotation, a suitable attenuation map for this phantom can be obtained from a 4-min TCT. A similar result is obtained for patients with thorax widths of <40 cm.


CONCLUSIONS
A sequential imaging protocol for acquiring a fast TCT can be used for attenuation correction of cardiac SPECT imaging. The sequential TCT can be acquired without significantly extending the duration of the imaging study. This method provides a way to perform attenuation correction on existing triple-head SPECT systems without extensively modifying the system.
Hollinger
E F
EF
Department of Diagnostic Radiology and Nuclear Medicine, Rush-Presbyterian-St. Luke's Medical Center, Chicago, Illinois 60612, USA.
Loncaric
S
S
Yu
D C
DC
Ali
A
A
Chang
W
W
D000328:Adult; D000465:Algorithms; D005240:Feasibility Studies; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008297:Male; D019047:Phantoms, Imaging; D012680:Sensitivity and Specificity; D013794:Thallium Radioisotopes; D013997:Time Factors; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*
D013794:Thallium Radioisotopes