Long-term results of intratumorous bleomycin-A5 injection for head and neck lymphangioma.
From June 1987 to June 1995, 200 patients with various types of head and neck lymphangioma were treated by intratumorous injection of bleomycin-A5. All 200 cases were followed from 2 to 10 years; 95 cases were followed for more than 5 years. The effective rate was 97%, and the curative rate was 86.5%. No pulmofibrosis or other serious complications were found. The relationships between the curative effect and tumor type, size, and side effect of bleomycin are discussed.
Zhong
P Q
PQ
Department of Head and Neck, Cancer Hospital of Shandong, Linyi, China.
Zhi
F X
FX
Li
R
R
Xue
J L
JL
Shu
G Y
GY
D000293:Adolescent; D000328:Adult; D000855:Anorexia / Q000139:chemically induced; D000903:Antibiotics, Antineoplastic / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D001761:Bleomycin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005334:Fever / Q000139:chemically induced; D005500:Follow-Up Studies; D006258:Head and Neck Neoplasms / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D015552:Injections, Intralesional; D008137:Longitudinal Studies; D008202:Lymphangioma / Q000188:drug therapy* / Q000473:pathology; D018191:Lymphangioma, Cystic / Q000188:drug therapy / Q000473:pathology; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D011658:Pulmonary Fibrosis / Q000517:prevention & control; D012074:Remission Induction
D000903:Antibiotics, Antineoplastic; D001761:Bleomycin