[Lipid peroxidation and the role of quaternary ammonium compounds in normalizing this process].
Regulation of lipid peroxidation is realized not only by antioxidant enzymes but by natural antioxidants as well. We have lately succeeded, together with the students, in identifying antioxidant properties of quaternary ammonium compounds, which fact makes it possible for the above properties to gain extensive applicability in a setting where there is this variety of disbolism. One of such drug preparations is ethonium. The article contains information about uses of ethonium in the tablet dose form. The tablets are of little toxicity, they stimulate the oxidation-reduction processes and proved to be effective in experimental gastric and duodenal ulcers.
Pis'ko
G T
GT
Kolomoets
M Iu
MIu
Meshchishen
I F
IF
Vasiliuk
V N
VN
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000897:Anti-Ulcer Agents / Q000008:administration & dosage / Q000494:pharmacology*; D000975:Antioxidants / Q000008:administration & dosage / Q000494:pharmacology*; D002908:Chronic Disease; D004341:Drug Evaluation; D004381:Duodenal Ulcer / Q000188:drug therapy / Q000201:enzymology; D005260:Female; D005753:Gastric Mucosa / Q000187:drug effects / Q000201:enzymology; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D000644:Quaternary Ammonium Compounds / Q000008:administration & dosage / Q000494:pharmacology*; D013276:Stomach Ulcer / Q000188:drug therapy / Q000201:enzymology; D013607:Tablets
D000897:Anti-Ulcer Agents; D000975:Antioxidants; D000644:Quaternary Ammonium Compounds; D013607:Tablets; C004921:Ethonium