Somatostatin immunoreactivity in esophageal premotor neurons of the rat.
Esophageal peristalsis is coordinated by premotor neurons localized to the central subnucleus of the nucleus of the solitary tract (NTScen). These premotor neurons project directly to motoneurons within the compact formation of the nucleus ambiguus (NAc). Somatostatin immunoreactive terminals have been previously demonstrated encircling motoneurons in the (NAc) (Cunningham, E.T., Jr. and Sawchenko, P.E., J. Neurosci., 9 (1989) 1668-1682). We combined transsynaptic tracing with pseudorabies virus and immunohistochemistry to localize somatostatin to premotor neurons within the NTScen.
Division of Gastroenterology and Nutrition, The Children's Hospital of Philadelphia, PA 19104, USA. broussard@email.chop.edu
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Broussard
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Bao
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Altschuler
D000818:Animals; D004947:Esophagus / Q000737:chemistry* / Q000166:cytology / Q000276:immunology; D007106:Immune Sera / Q000378:metabolism; D007124:Immunoenzyme Techniques; D007150:Immunohistochemistry; D008297:Male; D009046:Motor Neurons / Q000737:chemistry* / Q000276:immunology; D051381:Rats; D017207:Rats, Sprague-Dawley; D013004:Somatostatin / Q000032:analysis*
D007106:Immune Sera; D013004:Somatostatin