Survey of anthelmintic resistance on Danish horse farms, using 5 different methods of calculating faecal egg count reduction.
This study reports on the prevalence of anthelmintic resistance in strongyles of horses in Denmark. Of 5 methods used for the calculation of faecal egg count reduction (FECR) the method recommended by the World Association for the Advancement of Veterinary Parasitology, for the detection of resistance in sheep was the most sensitive procedure for detecting resistance. Using this method benzimidazole resistance was detected on 33 of 42 farms (79%) examined. Pyrantel was tested on 15 farms and FECR tests indicate resistance on 3 (30%) farms. On 2 farms on which resistance to pyrantel was detected resistance to benzimidazoles was also detected. On one of 16 farms examined ivermectin resistance was indicated at Day 14 but not at Day 19. On the 15 remaining farms ivermectin was effective. Due to the high prevalence of anthelmintic resistance in Danish horse herds it is recommended that tests of anthelmintic efficacy be conducted routinely to monitor the effectiveness of the strongyle control programmes.
Danish Veterinary Laboratory, Copenhagen V.
J
J
Craven
H
H
Bjørn
S A
SA
Henriksen
P
P
Nansen
M
M
Larsen
S
S
Lendal
D000818:Animals; D000871:Anthelmintics / Q000494:pharmacology* / Q000627:therapeutic use; D003718:Denmark; D004351:Drug Resistance; D005243:Feces / Q000469:parasitology*; D005273:Fenbendazole / Q000494:pharmacology / Q000627:therapeutic use; D005500:Follow-Up Studies; D006736:Horses; D007559:Ivermectin / Q000494:pharmacology / Q000627:therapeutic use; D010270:Parasite Egg Count / Q000379:methods / Q000662:veterinary*; D011716:Pyrantel Pamoate / Q000494:pharmacology / Q000627:therapeutic use; D013319:Strongyle Infections, Equine / Q000188:drug therapy* / Q000469:parasitology; D013320:Strongyloidea / Q000187:drug effects*
D000871:Anthelmintics; D005273:Fenbendazole; D007559:Ivermectin; D011716:Pyrantel Pamoate