Subacute cutaneous lupus erythematosus associated with cinnarizine and thiethylperazine therapy.
We report the case of a woman who developed subacute cutaneous lupus erythematosus (SCLE) after exposure to the sun while taking cinnarizine and thiethylperazine. The patient recalled that 10 years previously, a similar eruption had appeared after sunbathing, while she was taking only cinnarizine. SCLE development in this patient was probably drug related and there is some evidence that cinnarizine played an important pathogenic role.
Dermatology Department, Institut D'Investigacions Biomèdiques August Pi i Sunyer, Hospital Clinic, Faculty of Medicine, University of Barcelona, Spain.
A
A
Toll
P
P
Campo-Pisa
J
J
González-Castro
A
A
Campo-Voegeli
A
A
Azón
P
P
Iranzo
M
M
Lecha
C
C
Herrero
D000328:Adult; D000932:Antiemetics / Q000009:adverse effects*; D002936:Cinnarizine / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced* / Q000473:pathology; D010777:Photochemistry; D013847:Thiethylperazine / Q000009:adverse effects*
D000932:Antiemetics; D002936:Cinnarizine; D013847:Thiethylperazine