Prevalence of astroviruses in a children's hospital.
An enzyme immunoassay for astrovirus was used to screen 357 stool samples from 267 symptomatic inpatients at a tertiary-care children's hospital. Thirty stool samples from 26 patients contained astrovirus antigen, while rotavirus was found in 34 samples and Clostridium difficile toxin was found in 40. Half of the astrovirus infections were nosocomial. Additional pathogens were identified in six of the astrovirus antigen-positive stool samples. Most (80%) of the astroviruses recovered were of serotype 1. Astrovirus infections were significantly more common than rotavirus or C. difficile infections in very young infants and in those with surgical short-bowel syndrome.
Department of Pediatrics and Center for Digestive Disease, Stanford University, Stanford, California 94305-5208, USA.
S
S
Shastri
A M
AM
Doane
J
J
Gonzales
U
U
Upadhyayula
D M
DM
Bass
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000940:Antigenic Variation; D000956:Antigens, Viral / Q000032:analysis; D019350:Astroviridae Infections / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D005243:Feces / Q000821:virology; D006776:Hospitals, Pediatric; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D001257:Mamastrovirus / Q000145:classification / Q000302:isolation & purification*; D015995:Prevalence; D012703:Serotyping
D000956:Antigens, Viral