Neurodevelopmental outcome after open fetal surgery.
OBJECTIVE
This study examined the neurological and age-appropriate developmental outcomes of 11 children who underwent open fetal surgery.


RESULTS
Nine children have normal neurological outcomes, and nine have normal development.


CONCLUSIONS
Intensive postnatal care, intracranial hemorrhage, and requirement for prolonged respiratory support were associated with a worse neurological and developmental prognosis.
Gibbs
D L
DL
Fetal Treatment Center and the Department of Surgery, The University of California, San Francisco 94143-0570, USA.
Piecuch
R E
RE
Graf
J L
JL
Leonard
C H
CH
Farrell
J A
JA
Harrison
M R
MR
D002493:Central Nervous System Diseases / Q000175:diagnosis / Q000209:etiology; D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000601:surgery*; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D006548:Hernia, Diaphragmatic / Q000601:surgery*; D065630:Hernias, Diaphragmatic, Congenital; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009460:Neurologic Examination; D011247:Pregnancy; D011256:Pregnancy Outcome; D011379:Prognosis; D013514:Surgical Procedures, Operative / Q000009:adverse effects / Q000379:methods; D015996:Survival Rate; D016896:Treatment Outcome