[Boundaries of structure-functional units (domains) of eukaryotic chromosomes].
Extensive evidence indicates that eukaryotic chromosomes are organized as sets of structural-functional units (domains) that form the basis of independent gene activity. At present, several types of chromosome regions have been suggested for the role of putative domain boundaries between structural-functional units in eukaryotic chromosomes. In this review, the experimental data on several chromosome elements as possible boundaries in eukaryotic chromosomes are presented. They are: scs/scs'-elements of the Drosophila heat-shock locus, DCR, LCR and the insulator of the human and chicken beta-globin locus, as well as MARs (SARs) of plant and animal chromosomes.
Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, Russia.
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MV
Glazkov
D000818:Animals; D002874:Chromosome Mapping; D002875:Chromosomes; D004330:Drosophila / Q000235:genetics; D006360:Heat-Shock Proteins / Q000235:genetics; D006801:Humans; D010944:Plants / Q000235:genetics
D006360:Heat-Shock Proteins