Molecular events involved in differentiation of thyroid follicular cells.
Organogenesis is a complex event, often dependent on inductive tissue interactions, that ultimately promote expression and activation of a combinatorial sequence of transcription factors which are involved in controlling migration, growth and differentiation.
Missero
C
C
Stazione Zoologica A. Dohrn Villa Comunale, Naples, Italy.
Cobellis
G
G
De Felice
M
M
Di Lauro
R
R
D000818:Animals; D002454:Cell Differentiation; D002471:Cell Transformation, Neoplastic; D004268:DNA-Binding Proteins / Q000502:physiology; D051858:Forkhead Transcription Factors; D018507:Gene Expression Regulation, Developmental; D018398:Homeodomain Proteins / Q000502:physiology; D006801:Humans; D009687:Nuclear Proteins / Q000502:physiology; D000072636:PAX8 Transcription Factor; D051761:Paired Box Transcription Factors; D013961:Thyroid Gland / Q000166:cytology / Q000254:growth & development* / Q000378:metabolism; D013964:Thyroid Neoplasms / Q000235:genetics / Q000473:pathology; D000074482:Thyroid Nuclear Factor 1; D015534:Trans-Activators / Q000502:physiology; D014157:Transcription Factors / Q000235:genetics / Q000502:physiology*
D004268:DNA-Binding Proteins; D051858:Forkhead Transcription Factors; D018398:Homeodomain Proteins; D009687:Nuclear Proteins; D000072636:PAX8 Transcription Factor; C083325:PAX8 protein, human; D051761:Paired Box Transcription Factors; D000074482:Thyroid Nuclear Factor 1; D015534:Trans-Activators; D014157:Transcription Factors