The use of intraaortic balloon counterpulsation as an adjunct to reperfusion therapy in cardiogenic shock.
Modern coronary care unit interventions have not reduced the high mortality rate associated with cardiogenic shock due to acute myocardial infarction. Results with thrombolytic therapy have also been disappointing because of poor infarct artery patency rates in a low coronary flow state. Percutaneous transluminal coronary angioplasty appears to be a beneficial intervention, but the technique is not available at most hospitals. Intraaortic balloon counterpulsation provides temporary hemodynamic and clinical improvement in the majority of patients with cardiogenic shock. The use of intraaortic counterpulsation to augment patency rates with thrombolytic therapy or to stabilize patients for transfer to a hospital with angioplasty services appears to be a promising strategy for hospitals without an interventional cardiac catheterization laboratory.
Division of Cardiology, University of Michigan Medical Center, Ann Arbor 48109, USA.
E R
ER
Bates
R J
RJ
Stomel
J S
JS
Hochman
E M
EM
Ohman
D002986:Clinical Trials as Topic; D006439:Hemodynamics; D006801:Humans; D007423:Intra-Aortic Balloon Pumping; D009203:Myocardial Infarction / Q000150:complications* / Q000188:drug therapy / Q000503:physiopathology; D012770:Shock, Cardiogenic / Q000209:etiology / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D016019:Survival Analysis; D015912:Thrombolytic Therapy; D016896:Treatment Outcome