Control of poststroke involuntary and voluntary movement disorders with deep brain or epidural cortical stimulation.
The effects of deep brain or epidural cortical stimulation on poststroke involuntary and voluntary movement disorders were analyzed in a total of 64 patients. Among them, 22 patients underwent either deep brain or epidural cortical stimulation in order to control their poststroke involuntary movements. The remaining 42 underwent epidural cortical stimulation for the purpose of controlling their poststroke pain. In the latter group of patients, we analyzed the changes in coexistent involuntary or voluntary movement disorders during stimulation for pain control. Stimulation of either the thalamic nucleus ventralis intermedius or the motor cortex proved to be useful in 13 (59%) of the patients who underwent deep brain or epidural cortical stimulation for control of poststroke involuntary movements. Satisfactory control was often achieved in patients with hemiballismus, hemichorea or resting tremor. In 8 (19%) of the patients who underwent epidural cortical stimulation for pain control, stimulation of the motor cortex improved motor performance which had been impaired in association with hemiparesis. Such an effect was independent of pain control and apparently resulted from an inhibition of their rigidity. We believe that these findings justify further clinical studies on deep brain or epidural cortical stimulation for the control of poststroke movement disorders.
Katayama
Y
Y
Department of Neurological Surgery, Nihon University School of Medicine, Tokyo, Japan.
Fukaya
C
C
Yamamoto
T
T
D001921:Brain / Q000502:physiology*; D002561:Cerebrovascular Disorders / Q000150:complications* / Q000534:rehabilitation; D004599:Electric Stimulation Therapy; D004567:Electrodes, Implanted; D006801:Humans; D008297:Male; D008875:Middle Aged; D009044:Motor Cortex / Q000502:physiology*; D009069:Movement Disorders / Q000209:etiology / Q000534:rehabilitation / Q000628:therapy*; D059408:Pain Management; D013238:Stereotaxic Techniques; D013787:Thalamic Nuclei / Q000502:physiology; D016896:Treatment Outcome; D014202:Tremor / Q000628:therapy