[Preoperative CEA level predicts outcomes of hepatic resection for liver metastases from colorectal cancer].
We analyzed patients receiving hepatic resection for liver metastases from colorectal cancer to determine prognostic factors. Seventy-one patients underwent curative hepatic resection for liver metastases and 32 of them were treated with arterial infusion chemotherapy (AIC) using implantable port. Five-year survival rates in the AIC group and non-AIC group calculated by the method of Kaplan-Meier were 43% and 22%, respectively (p < 0.01, logrank test). By multivariate analysis calculated by the Cox proportional hazard model, the preoperative CEA level (cut point 10 ng/dl) and existence of AIC predicted survival.
Dept. of Surgery, Tokyo Metropolitan Bokutoh Hospital.
N
N
Umekita
T
T
Maeshiro
S
S
Miyamoto
T
T
Suzuki
S
S
Inoue
Y
Y
Awane
D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002272:Carcinoembryonic Antigen / Q000097:blood*; D015179:Colorectal Neoplasms / Q000473:pathology*; D003131:Combined Modality Therapy; D004317:Doxorubicin / Q000008:administration & dosage; D005472:Fluorouracil / Q000008:administration & dosage; D006498:Hepatectomy; D006499:Hepatic Artery; D006801:Humans; D007261:Infusions, Intra-Arterial; D008113:Liver Neoplasms / Q000188:drug therapy / Q000276:immunology / Q000556:secondary* / Q000601:surgery*; D011379:Prognosis; D015996:Survival Rate; D016896:Treatment Outcome
D002272:Carcinoembryonic Antigen; D004317:Doxorubicin; D005472:Fluorouracil