Chemiluminescence accompanying oxidation of bopindolol.
The oxidation of bopindolol using the Co-ethylenediaminetetraacetic acid (EDTA) + H2O2 system was investigated by spectrophotometric, chemiluminescence, and fluorescence methods. The effects of oxygen free radicals scavengers and 1O2 quenchers on the light emission were measured. The obtained results show the electronically excited products of the bopindolol degradation are involved in the oxidation process.
Biological & Medical Research Department, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia. enein@kfshrc.edu.sa
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Aboul-Enein
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Kruk
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Lichszteld
D000319:Adrenergic beta-Antagonists / Q000737:chemistry*; D002021:Buffers; D003035:Cobalt; D004492:Edetic Acid; D006861:Hydrogen Peroxide; D008163:Luminescent Measurements; D015394:Molecular Structure; D010084:Oxidation-Reduction; D010869:Pindolol / Q000031:analogs & derivatives* / Q000737:chemistry; D013050:Spectrometry, Fluorescence / Q000379:methods; D013053:Spectrophotometry / Q000379:methods
D000319:Adrenergic beta-Antagonists; D002021:Buffers; D003035:Cobalt; D004492:Edetic Acid; D006861:Hydrogen Peroxide; D010869:Pindolol; C018021:cobaltous chloride; C036007:bopindolol