Endoprosthetic treatment of metastatic pathological fractures.
Due to a prolonged time of survival patients with lowrisk skeletal dissemination may develop a local relapse after surgical treatment of a pathological fracture. In a series of 180 patients with bone metastases of breast cancer, a local metastatic recurrency was observed 8-36 months after operative treatment in 12 patients. All of them had a receptor-positive primary and were free from visceral metastases; only one had received radiotherapy postoperatively. Patients with low-risk disease therefore should undergo more radial surgical procedures than patients with poor prognosis, in whom reconstitution of stability represents the most important therapeutic goal. In cases with low-risk disease and histologically proven residual tumour a postoperative irradiation should be administered as a rule.
Abteilung für Unfallchirurgie, Hand- und Wiederherstellungschirurgie, Universität Ulm, Germany.
M
M
Schulte
E
E
Hartwig
M
M
Sarkar
M
M
Arand
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001843:Bone Cements; D001859:Bone Neoplasms / Q000150:complications* / Q000556:secondary* / Q000601:surgery; D001943:Breast Neoplasms / Q000473:pathology*; D005260:Female; D005598:Fractures, Spontaneous / Q000601:surgery*; D006801:Humans; D008875:Middle Aged; D019919:Prosthesis Implantation; D012307:Risk Factors
D001843:Bone Cements