Immunoproliferative small intestinal disease in a 16-year-old boy presenting as severe malabsorption with excellent response to tetracycline treatment.
Immunoproliferative small intestinal disease (IPSID) is a rare lympho-proliferative disorder of the upper small intestine. It is considered a special form of MALT lymphoma with propensity to malignant transformation. This disorder is rare in pediatric literature. We report a case of IPSID in a 16-year-old boy with low-grade malignant transformation, presenting as severe malnutrition and a possible association with Helicobacter pylori. The patient responded well to an extended treatment with tetracycline and eradication of H. pylori.
Department of Gastroenterology, Maimonides Medical Center, Brooklyn, NY 11219, USA.
A
A
Zamir
G
G
Parasher
A A
AA
Moukarzel
L
L
Guarini
L
L
Zeien
F
F
Feldman
D000293:Adolescent; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D007161:Immunoproliferative Small Intestinal Disease / Q000150:complications / Q000175:diagnosis* / Q000382:microbiology / Q000473:pathology; D007421:Intestine, Small / Q000473:pathology; D008286:Malabsorption Syndromes / Q000209:etiology*; D008297:Male; D013270:Stomach / Q000382:microbiology