Experimental infection in SPF kittens with a particular calicivirus strain originally isolated from lion.
Two SPF kittens were experimentally infected via the intranasal route with a strain of calicivirus originally isolated from sick lion suffering from vesicular disease. Fever, 40.3 degrees C and 40.7 degrees C, and vesicular formation in tongue and snout were reproduced in both kittens. The infected virus was recovered from nasal, oral and rectal swabs. A longer duration of virus recovery was proved with oral swab samples taken from 1 to 10 and 12 days post infection. This suggests that tongue and oral tissues are the main tissues for virus multiplication.
Department of Veterinary Medicine, College of Bioresource Sciences, Nihon University, Kanagawa, Japan.
K
K
Kadoi
H
H
Kamata
S
S
Ohba
T
T
Satoh
Y
Y
Inaba
D000281:Administration, Intranasal; D000367:Age Factors; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D000918:Antibody Specificity; D002139:Caliciviridae / Q000145:classification / Q000302:isolation & purification; D017250:Caliciviridae Infections / Q000276:immunology / Q000662:veterinary* / Q000821:virology; D002371:Cat Diseases / Q000821:virology*; D002415:Cats; D005334:Fever / Q000662:veterinary / Q000821:virology; D008045:Lions / Q000821:virology; D009666:Nose / Q000473:pathology / Q000821:virology; D013047:Specific Pathogen-Free Organisms; D013997:Time Factors; D014059:Tongue / Q000473:pathology
D000914:Antibodies, Viral