Possible biochemical mode of anti-inflammatory action of Azadirachta indica A. Juss. in rats.
The water soluble part of alcoholic extract of A. indica leaves at a dose of 200 mg/kg, p.o., exerted significant antiinflammatory activity in cotton pellet granuloma assay in rats. The extract also inhibited significantly the biochemical parameters (viz. DNA, RNA, lipid peroxide, acid phosphatase and alkaline phosphatase) studied in cotton pellet exudate.
Biometry Research Unit, Indian Statistical Institute, Calcutta, India.
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Chattopadhyay
D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000494:pharmacology*; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry*; D051381:Rats; D017208:Rats, Wistar
D000894:Anti-Inflammatory Agents, Non-Steroidal; D010936:Plant Extracts