Adjusting immunosuppression to the identification of T-cell activating mediators in rejecting transplants: a novel approach to rejection diagnosis and treatment.
Department of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
J
J
Strehlau
W
W
Maslinski
D
D
Chae
M
M
Pavlakis
J H
JH
Ehrich
T B
TB
Strom
D000069594:Abatacept; D000328:Adult; D015703:Antigens, CD; D000943:Antigens, Differentiation / Q000235:genetics / Q000502:physiology; D060908:CTLA-4 Antigen; D002478:Cells, Cultured; D016207:Cytokines / Q000235:genetics / Q000494:pharmacology / Q000502:physiology*; D003907:Dexamethasone / Q000494:pharmacology; D053222:Fas Ligand Protein; D005786:Gene Expression Regulation / Q000187:drug effects; D006084:Graft Rejection / Q000175:diagnosis / Q000276:immunology* / Q000628:therapy; D053804:Granzymes; D006801:Humans; D018796:Immunoconjugates; D007165:Immunosuppression Therapy / Q000379:methods*; D007166:Immunosuppressive Agents / Q000494:pharmacology; D019409:Interleukin-15 / Q000235:genetics / Q000494:pharmacology / Q000502:physiology; D007376:Interleukin-2 / Q000494:pharmacology / Q000502:physiology; D015851:Interleukin-7 / Q000494:pharmacology / Q000502:physiology; D007700:Kinetics; D008213:Lymphocyte Activation / Q000187:drug effects; D008562:Membrane Glycoproteins / Q000235:genetics; D054353:Perforin; D011090:Polyenes / Q000494:pharmacology*; D016133:Polymerase Chain Reaction; D052899:Pore Forming Cytotoxic Proteins; D011994:Recombinant Proteins / Q000494:pharmacology; D012016:Reference Values; D012697:Serine Endopeptidases / Q000235:genetics; D020123:Sirolimus; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology*; D014158:Transcription, Genetic / Q000187:drug effects*
D015703:Antigens, CD; D000943:Antigens, Differentiation; D060908:CTLA-4 Antigen; C556706:CTLA4 protein, human; D016207:Cytokines; C505661:FASLG protein, human; D053222:Fas Ligand Protein; D018796:Immunoconjugates; D007166:Immunosuppressive Agents; D019409:Interleukin-15; D007376:Interleukin-2; D015851:Interleukin-7; D008562:Membrane Glycoproteins; D011090:Polyenes; D052899:Pore Forming Cytotoxic Proteins; D011994:Recombinant Proteins; D054353:Perforin; D000069594:Abatacept; D003907:Dexamethasone; C509213:GZMB protein, human; D053804:Granzymes; D012697:Serine Endopeptidases; D020123:Sirolimus