Heat shock protects synaptic transmission in flight motor circuitry of locusts.
We investigated the effects of heat shock on the temperature sensitivity of synaptic transmission in the motor circuit for flight in Locusta migratoria. In heat shocked animals synaptic transmission failed at 5-6 degrees C higher than in control animals and recovery of transmission was more than three times faster upon return to room temperature. We also found that synaptic delay was rendered insensitive to increases in temperature by heat shock. Thus we have shown in the locust that heat shock has important protective effects on synaptic transmission, thereby extending the upper temperature limit for the motor patterns that generate flight. This is the first description of an effect of heat shock that preserves neuronal communication under subsequent stressful conditions.
Dawson-Scully
K
K
Department of Biology, Queen's University, Kingston, Ontario, Canada.
Meldrum Robertson
R
R
D000818:Animals; D004558:Electric Stimulation; D004594:Electrophysiology; D019706:Excitatory Postsynaptic Potentials / Q000502:physiology; D005426:Flight, Animal / Q000502:physiology*; D017952:Ganglia, Invertebrate / Q000166:cytology / Q000502:physiology; D006110:Grasshoppers / Q000502:physiology*; D006358:Hot Temperature; D066298:In Vitro Techniques; D007395:Interneurons / Q000502:physiology; D009046:Motor Neurons / Q000502:physiology*; D009132:Muscles / Q000294:innervation / Q000502:physiology*; D019581:Neuropil / Q000502:physiology; D013569:Synapses / Q000502:physiology; D009435:Synaptic Transmission / Q000502:physiology*