Apoptosis regulation and its applications to biotechnology.
Increased knowledge of the molecular interactions that characterize the control of apoptosis is identifying possible novel approaches to inhibit cell death and generate enhanced viable cell biomass. The application of such approaches to recombinant mammalian cells promises to improve the cost-effectiveness of industrial-scale protein expression.
Biochemistry Research Division, School of Biological Sciences, University of Manchester, UK. alan.dickson@man.ac.uk
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D000818:Animals; D017209:Apoptosis / Q000502:physiology*; D001709:Biotechnology / Q000639:trends*; D018929:Cell Culture Techniques / Q000639:trends*; D005057:Eukaryotic Cells / Q000166:cytology*