Second primary tumours in more than 2-year disease-free survivors of small-cell lung cancer in Japan: the role of smoking cessation.
Patients with small-cell lung cancer who survive more than 2 years have a significantly increased risk (relative risk of 3.6) of developing a second primary tumour. The cessation of cigarette smoking after successful therapy is associated with a significantly decreased risk of a second primary tumour.
National Kinki Central Hospital for Chest Diseases, Sakai, Osaka, Japan.
M
M
Kawahara
S
S
Ushijima
T
T
Kamimori
N
N
Kodama
M
M
Ogawara
K
K
Matsui
N
N
Masuda
M
M
Takada
T
T
Sobue
K
K
Furuse
D000368:Aged; D018288:Carcinoma, Small Cell / Q000453:epidemiology*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000453:epidemiology*; D012306:Risk; D016540:Smoking Cessation