Reversible activation of prophenoloxidase with 2-propanol in Drosophila melanogaster.
In Drosophila melanogaster, activation of prophenoloxidase with 2-propanol was analyzed. Prophenoloxidases A1 and A3 were activated within 1 sec after addition of 2-propanol. Activation of prophenoloxidase with 2-propanol is considered to be a reversible conformational change of the prophenoloxidase protein.
Biological Laboratory, Faculty of Science, Okayama University of Science, Japan. asada@das.ous.ac.jp
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Asada
D019840:2-Propanol / Q000494:pharmacology*; D000818:Animals; D004156:Catechol Oxidase / Q000378:metabolism*; D004331:Drosophila melanogaster; D004792:Enzyme Precursors / Q000378:metabolism*; D007527:Isoenzymes / Q000378:metabolism*; D007700:Kinetics; D011487:Protein Conformation
D004792:Enzyme Precursors; D007527:Isoenzymes; C038451:pro-phenoloxidase; D004156:Catechol Oxidase; D019840:2-Propanol