Rhesus anti-D immunoglobulin in chronic autoimmune neuropathy.
OBJECTIVE
To investigate the effect of Rhesus anti-D immunoglobulin (anti-D) in patients with an autoimmune demyelinating neuropathy.


METHODS
Three patients with an autoimmune mediated neuropathy received 1000 IU anti-D weekly for 2 months.


RESULTS
Two patients worsened gradually during the treatment and 1 remained unchanged.


CONCLUSIONS
Rhesus anti-D immunoglobulin has no beneficial effect in patients with autoimmune neuropathy.
Department of Neurology, University Hospital Groningen, The Netherlands.
A E
AE
de Jager
C A
CA
Hazenberg
J H
JH
van der Hoeven
D000328:Adult; D001327:Autoimmune Diseases / Q000175:diagnosis / Q000276:immunology / Q000628:therapy*; D002908:Chronic Disease; D003711:Demyelinating Diseases / Q000175:diagnosis / Q000276:immunology / Q000628:therapy*; D006801:Humans; D007273:Injections, Intramuscular; D007518:Isoantibodies / Q000097:blood / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D016472:Motor Neuron Disease / Q000175:diagnosis / Q000276:immunology / Q000628:therapy*; D009046:Motor Neurons / Q000187:drug effects; D009460:Neurologic Examination / Q000187:drug effects; D012204:Rh-Hr Blood-Group System / Q000097:blood*; D018029:Rho(D) Immune Globulin; D011984:Sensory Receptor Cells / Q000187:drug effects; D016896:Treatment Outcome
D007518:Isoantibodies; C061961:RHO(D) antibody; D012204:Rh-Hr Blood-Group System; D018029:Rho(D) Immune Globulin