title: Susceptibilities of Candida species isolated from the lower gastrointestinal tracts of high-risk patients to the new semisynthetic echinocandin LY303366 and other antifungal agents.
abstract: Fifty-two percent of stool specimens collected from 1,200 high-risk patients were colonized with yeasts, primarily Candida albicans (53. 6%) and Candida glabrata (35.7%). Susceptibilities to all antifungal agents tested, including LY303366, were similar to those reported previously for Candida species isolated from blood.
authors.affiliation: Department of Medical Microbiology, University of Manitoba, Canada ggzhanel@pcs.mb.ca
authors.forename: G G
authors.initials: GG
authors.lastname: Zhanel
authors.forename: J A
authors.initials: JA
authors.lastname: Karlowsky
authors.forename: S A
authors.initials: SA
authors.lastname: Zelenitsky
authors.forename: M A
authors.initials: MA
authors.lastname: Turik
authors.forename: D J
authors.initials: DJ
authors.lastname: Hoban
mesh_terms: D000077612:Anidulafungin; D000935:Antifungal Agents / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects*; D004064:Digestive System / Q000382:microbiology*; D054714:Echinocandins; D006801:Humans; D008826:Microbial Sensitivity Tests; D010456:Peptides, Cyclic / Q000494:pharmacology*; D012306:Risk
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D010456:Peptides, Cyclic; D000077612:Anidulafungin