[Myositis proliferans: a pseudosarcomatous lesion in soft tissue].
Myositis proliferans is a reactive, intramuscular soft tissue disease characterized by fibroblast and myofibroblast proliferation, showing similarities to the phase-like development seen in the general pathology of wound healing and hypertrophic scars. Immunohistochemically, a combined expression of vimentin and alpha-sm actin is seen in the spindle-shaped cell formations. The decisive histological preparations is supported by immunohistochemical techniques, especially in the differentiation from sarcoma. If a definite diagnosis is made, incomplete excision may suffice.
Alex
O
O
Institut für Pathologie an den Berufsgenossenschaftlichen, Klinikum der Ruhruniversität Bochum.
Wiethege
T
T
Müller
K M
KM
D000199:Actins / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D002455:Cell Division / Q000502:physiology; D017439:Cicatrix, Hypertrophic / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D005350:Fibroma / Q000473:pathology*; D015726:Giant Cells / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D019042:Muscle Neoplasms / Q000473:pathology*; D018482:Muscle, Skeletal / Q000473:pathology; D009220:Myositis / Q000473:pathology*; D014746:Vimentin / Q000032:analysis; D014945:Wound Healing / Q000502:physiology
D000199:Actins; D014408:Biomarkers, Tumor; D014746:Vimentin