Disseminated coccidioidomycosis associated with hypercalcemia.
This article describes a patient in whom disseminated infection with coccidioidomycosis was associated with hypercalcemia. The patient had a low level of 1,25-dihydroxyvitamin D and a suppressed parathyroid hormone value, an indication that the hypercalcemia was not mediated by vitamin D or parathyroid hormone. The episode resolved readily with administration of pamidronate, an outcome suggesting that this is effective treatment of hypercalcemia of this origin. On follow-up of the patient while he was receiving antifungal therapy for Coccidioides immitis, calcium values remained normal.
Westphal
S A
SA
Department of Medicine, Maricopa Medical Center, Phoenix, Arizona, USA.
D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use; D001842:Bone and Bones / Q000187:drug effects; D003047:Coccidioidomycosis / Q000150:complications* / Q000188:drug therapy; D004164:Diphosphonates / Q000627:therapeutic use; D006801:Humans; D006934:Hypercalcemia / Q000188:drug therapy / Q000382:microbiology*; D008297:Male; D000077268:Pamidronate
D000935:Antifungal Agents; D004164:Diphosphonates; D000077268:Pamidronate