title: Pachymeningitis with multiple cranial neuropathies and unilateral optic neuropathy secondary to Pseudomonas aeruginosa: case report and review.
abstract: Hypertrophic cranial pachymeningitis is a rare disorder that frequently presents with multiple cranial neuropathies. This disorder, which is characterized by thickening and infiltration of the cranial dura, can result from a variety of inflammatory and infectious conditions. A patient with hypertrophic cranial pachymeningitis is described in whom meningeal biopsy and bacterial cultures of the biopsy specimen revealed Pseudomonas aeruginosa. The authors believe this to be the first documented case of pachymeningitis secondary to this organism.
authors.affiliation: Department of Ophthalmology, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Girkin
authors.forename: J D
authors.initials: JD
authors.lastname: Perry
authors.forename: N R
authors.initials: NR
authors.lastname: Miller
authors.forename: S G
authors.initials: SG
authors.lastname: Reich
mesh_terms: D002442:Ceftazidime / Q000627:therapeutic use; D003389:Cranial Nerve Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D006801:Humans; D006984:Hypertrophy; D008279:Magnetic Resonance Imaging; D008297:Male; D008578:Meninges / Q000382:microbiology / Q000473:pathology; D016920:Meningitis, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D008875:Middle Aged; D009901:Optic Nerve Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D010243:Paralysis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D011552:Pseudomonas Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification*; D014031:Tobramycin / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D002442:Ceftazidime; D014031:Tobramycin