Simvastatin-induced lupus erythematosus.
We report the case of a 79-year-old man who had onset of fatigue, myalgia, and pleuritic chest pain 3 months after initiation of therapy with simvastatin. He had signs of pleuropericarditis due to simvastatin-induced lupus erythematosus. This should alert clinicians to this possible adverse effect of simvastatin and other statins.
Khosla
R
R
Wright State University School of Medicine, Department of Medicine, Dayton, Ohio, USA.
Butman
A N
AN
Hammer
D F
DF
D000368:Aged; D000924:Anticholesteremic Agents / Q000009:adverse effects*; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000139:chemically induced*; D008297:Male; D019821:Simvastatin / Q000009:adverse effects*
D000924:Anticholesteremic Agents; D019821:Simvastatin