title: Genotyping in clinical trials: towards a principle of informed request.
abstract: This paper reviews the usefulness of bioethical instruments such as the informed consent principle to handle ethical and political challenges of clinical trials in genotyping and DNA-banking and discusses an informed request model as well as other contractual relations between research institutions, patients, and their families.
authors.affiliation: Ruhr Universität Bochum, Germany.
authors.forename: H M
authors.initials: HM
authors.lastname: Sass
mesh_terms: D001675:Bioethics; D018070:Biological Specimen Banks; D002986:Clinical Trials as Topic; D003219:Confidentiality; D032962:Consent Forms; D032982:Contracts; D004247:DNA; D030561:Databases, Nucleic Acid; D030661:Genetic Privacy; D036281:Genetic Research; D005838:Genotype; D006801:Humans; D007258:Informed Consent; D008499:Medical Records; D026706:Paternalism; D010344:Patient Advocacy; D026684:Personal Autonomy; D035842:Research Subjects; D035844:Researcher-Subject Relations; D018570:Risk Assessment
chemical_list: D004247:DNA