title: Determination and estimation of water solubilities and octanol/water partition coefficients for derivates of benzanilides.
abstract: A shake-flask method was used to determine the water solubilities (Sw) and the octanol/water partition coefficients(Kow) of 14 derivates of benzanilides. The results showed that the octanol/water partition coefficients were correlated (r=-0.93) with Sw. The linear solvation energy relationship(LSER) and molecular connectivity methods have been used to establish correlation equation successfully. The LSER method was used to predict these partitioning properties more accurately. The estimated values were well fitted with observed ones.
authors.affiliation: Department of Environmental Science and Engineering, Nanjing University, P.R. China.
authors.forename: J
authors.initials: J
authors.lastname: Dai
authors.forename: L
authors.initials: L
authors.lastname: Jin
authors.forename: L
authors.initials: L
authors.lastname: Wang
authors.forename: Z
authors.initials: Z
authors.lastname: Zhang
mesh_terms: D001549:Benzamides / Q000737:chemistry*; D000442:Octanols / Q000737:chemistry; D010575:Pesticides / Q000737:chemistry; D012995:Solubility; D014874:Water Pollutants, Chemical / Q000493:pharmacokinetics*
chemical_list: D001549:Benzamides; D000442:Octanols; D010575:Pesticides; D014874:Water Pollutants, Chemical