Output-to-input approach to neural plasticity in vestibular pathways.
Some thoughts on current interpretations of available data regarding vestibular compensation at functional, network, and neural levels are presented. Basic concepts related to neural plasticity (or elasticity) underlying motor learning and regeneration also are discussed briefly. Modifiability in vestibular pathways, at both the functional and structural levels, after peripheral and central axotomy, and subsequent to transient or permanent chemical target removal, is presented as an experimental ground to explain similarities and differences between regenerative, compensatory, and adaptive mechanisms in the mammal central nervous system.
Delgado-García
J M
JM
Laboratorio de Neurociencia, Facultad de Biología, Universidad de Sevilla, Seville, Spain.
D000010:Abducens Nerve / Q000187:drug effects / Q000601:surgery; D000222:Adaptation, Physiological; D000818:Animals; D001905:Botulinum Toxins / Q000494:pharmacology; D002415:Cats; D007758:Ear, Inner / Q000601:surgery; D005133:Eye Movements / Q000502:physiology; D019416:Head Movements; D009046:Motor Neurons / Q000187:drug effects / Q000502:physiology; D009473:Neuronal Plasticity; D009801:Oculomotor Muscles / Q000294:innervation / Q000502:physiology; D014722:Vestibule, Labyrinth / Q000294:innervation*
D001905:Botulinum Toxins