title: UV-Guided isolation of alantrypinone, a novel Penicillium alkaloid.
abstract: Fumiquinazoline F (1) and alantrypinone (2) have been isolated as the two major metabolites of Penicillium thymicola. The structure of 2, which contains a new ring structure, was elucidated by analysis of spectroscopic data including 2D NMR. The absolute configuration of 2 was established by a single-crystal X-ray diffraction study.
authors.affiliation: Mycology Group, Department of Biotechnology, Technical University of Denmark, DK-2800 Lyngby, Denmark. TOL@IBT.DTU.DK
authors.forename: T O
authors.initials: TO
authors.lastname: Larsen
authors.forename: K
authors.initials: K
authors.lastname: Frydenvang
authors.forename: J C
authors.initials: JC
authors.lastname: Frisvad
authors.forename: C
authors.initials: C
authors.lastname: Christophersen
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D002240:Carbohydrate Sequence; D018360:Crystallography, X-Ray; D007211:Indoles; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D008969:Molecular Sequence Data; D010407:Penicillium / Q000737:chemistry*; D011799:Quinazolines; D013056:Spectrophotometry, Ultraviolet
chemical_list: D000470:Alkaloids; D007211:Indoles; D011799:Quinazolines; C115545:alantrypinone