title: Evolution of chromosome Y in primates.
abstract: We have investigated, by fluorescence in situ hybridization (FISH), the cytogenetic evolution of the Y chromosome in primates using 17 yeast artificial chromosomes, representative of the Y-specific euchromatic region of the human chromosome Y. The FISH experiments were performed on great apes (Homo sapiens, Pan troglodytes, Gorilla gorilla and Pongo pygmaeus pygmaeus), and on two Old World monkeys species as an outgroup (Cercopitecidae Macaca fascicularis and Papio anubis). The results showed that this peculiar chromosome has undergone rapid and unconstrained evolution both in sequence content and organization.
authors.affiliation: Istituto di Genetica, Via Amendola 165/A, I-70126 Bari, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Archidiacono
authors.forename: C T
authors.initials: CT
authors.lastname: Storlazzi
authors.forename: C
authors.initials: C
authors.lastname: Spalluto
authors.forename: A S
authors.initials: AS
authors.lastname: Ricco
authors.forename: R
authors.initials: R
authors.lastname: Marzella
authors.forename: M
authors.initials: M
authors.lastname: Rocchi
mesh_terms: D000818:Animals; D002520:Cercopithecidae / Q000235:genetics; D018244:Chromosomes, Artificial, Yeast; D004303:Dosage Compensation, Genetic; D019143:Evolution, Molecular; D006071:Gorilla gorilla / Q000235:genetics; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008252:Macaca fascicularis / Q000235:genetics; D002679:Pan troglodytes / Q000235:genetics; D010215:Papio / Q000235:genetics; D011148:Pongo pygmaeus / Q000235:genetics; D011323:Primates / Q000235:genetics*; D011544:Pseudogenes; D012689:Sequence Homology, Nucleic Acid; D013045:Species Specificity; D014960:X Chromosome / Q000235:genetics; D014998:Y Chromosome / Q000235:genetics*