title: PM and D1S80 loci gene frequencies in the Zaragoza population of northern Spain.
abstract: LDLR, GYPA, HBGG, D7S8, GC (PM loci) and D1S80 are widely used in forensic casework analyses and population data are required to estimate the frequency of a DNA profile. This paper presents the results of a survey aimed at investigating the allele and genotype frequency distribution of these loci in an important Spanish population (Zaragoza, North Spain). Statistical analysis to determine whether allele frequencies were in Hardy-Weinberg equilibrium was carried out as well as to obtain some parameters of medicolegal interest. There was no evidence of association between the alleles of the loci. The Zaragoza sample does not differ substantially from other Caucasian populations.
authors.affiliation: Department of Legal Medicine, University of Zaragoza, Spain.
authors.forename: B
authors.initials: B
authors.lastname: Martinez-Jarreta
authors.forename: B
authors.initials: B
authors.lastname: Budowle
authors.forename: E
authors.initials: E
authors.lastname: Abecia
authors.forename: B
authors.initials: B
authors.lastname: Bell
authors.forename: Y
authors.initials: Y
authors.lastname: Casalod
authors.forename: M
authors.initials: M
authors.lastname: Castellano
mesh_terms: D000483:Alleles; D004247:DNA / Q000032:analysis*; D016172:DNA Fingerprinting / Q000379:methods; D005787:Gene Frequency; D008040:Genetic Linkage; D005819:Genetic Markers; D014644:Genetic Variation; D006801:Humans; D018598:Minisatellite Repeats / Q000235:genetics*; D016133:Polymerase Chain Reaction; D044469:Racial Groups / Q000235:genetics; D013030:Spain; D014809:Vitamin D-Binding Protein / Q000235:genetics*
chemical_list: D005819:Genetic Markers; D014809:Vitamin D-Binding Protein; D004247:DNA