title: Recovery of minimal change nephrotic syndrome and acute renal failure in a patient withRenal cell carcinoma.
abstract: We describe a 78-year-old patient with nephrotic syndrome due to minimal-change glomerulopathy, associated with a renal adenocarcinoma. Oliguric acute renal failure requiring hemodialysis was also observed. Surgical removal of the tumor and corticosteroid therapy resulted in resolution of the nephrotic state and improvement of the renal function. Nephrotic syndrome is an unusual complication of renal cell carcinomas, and the association of minimal-change glomerulopathy (MCG) and solid tumors is particularly uncommon. In spite of this, MCG should be considered in the nephropathies causing nephrotic syndrome and acute renal failure in patients with renal malignancies.
authors.affiliation: Department of Internal Medicine, Hospital Universitari Joan XXIII, Rovira i Virgili University, Tarragona, Spain.
authors.forename: T
authors.initials: T
authors.lastname: Auguet
authors.forename: A
authors.initials: A
authors.lastname: Lorenzo
authors.forename: E
authors.initials: E
authors.lastname: Colomer
authors.forename: A
authors.initials: A
authors.lastname: Zamora
authors.forename: C
authors.initials: C
authors.lastname: García
authors.forename: A
authors.initials: A
authors.lastname: Martínez-Vea
authors.forename: C
authors.initials: C
authors.lastname: Richart
authors.forename: J A
authors.initials: JA
authors.lastname: Oliver
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology* / Q000628:therapy; D000368:Aged; D002292:Carcinoma, Renal Cell / Q000150:complications* / Q000601:surgery; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications* / Q000601:surgery; D008297:Male; D009402:Nephrosis, Lipoid / Q000188:drug therapy / Q000209:etiology*; D011379:Prognosis