title: Bile acids, fibre and colon cancer: the story unfolds.
abstract: Are the changes in faecal bile acid concentrations the cause of colorectal cancer or one of its effects? This is an area of controversy mainly due to the lack of a clear explanation as to how the bile acid concentrations are controlled under different circumstances. This review presents an outline of the evidence that bile acids are both a causal factor in colorectal cancer and that their concentrations are affected by it in a synergistic manner. It also offers an explanation of how some dietary fibre protects against colorectal cancer.
authors.affiliation: Food Research Centre, South Bank University, London.
authors.forename: M F
authors.initials: MF
authors.lastname: Chaplin
mesh_terms: D001647:Bile Acids and Salts / Q000378:metabolism*; D002784:Cholesterol / Q000378:metabolism; D015179:Colorectal Neoplasms / Q000453:epidemiology / Q000209:etiology*; D004043:Dietary Fiber; D006801:Humans; D012307:Risk Factors
chemical_list: D001647:Bile Acids and Salts; D004043:Dietary Fiber; D002784:Cholesterol