title: [Acute retinal necrosis syndrome. Argon laser coagulation for prevention of rhegmatogenic retinal detachment].
abstract: BACKGROUND
  ARN syndrome follows severeintraocular infection by herpes viruses and primarily affects the peripheral retina. Following scar formation, despite antiviral treatment, rhegmatogenous retinal detachment occurs very often. Prophylactic argon laser photocoagulation has therefore been proposed. We report our experience.
  
  
  METHODS
  We treated five patients presenting clinically with advanced unilateral ARN with acyclovir. All eyes received a prophylactic confluent double row of argon laser treatment (500 microns, 0.2 s, gray-white lesions) central to the affected area as soon as was possible, depending on the vitreous clouding. Four patients were treated with Aspirin.
  
  
  RESULTS
  One of the five patients had a peripheral rhegmatogenous retinal detachment that was limited by the argon laser row. Another patient had a tractional detachment needing vitreoretinal surgery. Two eyes developed vitreal hemorrhage of unknown origin.
  
  
  CONCLUSIONS
  A lower rate of rhegmatogenous retinal detachments than expected occurred post-laser treatment. Vitreal hemorrhage was more frequent than previously reported. The bleeding probably originated from anterior retinal neovascularization and may have been enhanced by Aspirin treatment. We recommend early prophylactic argon laser photocoagulation in all ARN patients in agreement with the results of previous studies.
authors.affiliation: Augenklinik, Heinrich-Heine-Universität Düsseldorf.
authors.forename: T
authors.initials: T
authors.lastname: Hudde
authors.forename: C
authors.initials: C
authors.lastname: Althaus
authors.forename: R
authors.initials: R
authors.lastname: Sundmacher
mesh_terms: D000212:Acyclovir / Q000008:administration & dosage; D000328:Adult; D000368:Aged; D000998:Antiviral Agents / Q000008:administration & dosage; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D017075:Laser Coagulation; D008297:Male; D008875:Middle Aged; D012163:Retinal Detachment / Q000175:diagnosis / Q000517:prevention & control* / Q000601:surgery; D015882:Retinal Necrosis Syndrome, Acute / Q000175:diagnosis / Q000601:surgery*; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D000212:Acyclovir