Embryonic globins of the marsupial the Tammar Wallaby (Macropus eugenii): bird like and mammal like.
1. Tammar Wallaby embryonic blood has been shown to have three alpha-like and two beta-like globin chains in its four haemoglobin components and partial sequences of several chains have been determined. 2. The major embryonic beta-like chain (epsilon) is similar to other mammalian embryonic beta-like chains on the basis of sequencing its first 60 amino acids. 3. There is another embryonic beta-like chain present in one haemoglobin component. It was designated omega and, in its first 54 amino acids, it has features that are more like avian globins than mammalian globins. 4. The one alpha-like embryonic globin sequenced has mammalian rather than avian characteristics. 5. A provisional phylogenetic tree of beta-like globins has been determined. The Tammar epsilon-globin forms a monophyletic group with marsupial and other mammalian embryonic globins; the omega-globin forms a monophyletic group with bird adult and embryonic globins.
Holland
R A
RA
School of Physiology and Pharmacology, University of New South Wales, Australia. r.holland@unsw.edu.au
Gooley
A A
AA
Hope
R M
RM
D000595:Amino Acid Sequence; D000818:Animals; D006454:Hemoglobins / Q000502:physiology*; D006801:Humans; D046911:Macromolecular Substances; D007614:Macropodidae / Q000097:blood* / Q000196:embryology*; D008969:Molecular Sequence Data; D010802:Phylogeny; D017386:Sequence Homology, Amino Acid
D006454:Hemoglobins; D046911:Macromolecular Substances