title: The effect of triiodothyronine on cell oxidative capacity in regenerating rat liver.
abstract: The recovery of total DNA content and recovery of total cytochrome c oxidase activity in the rat liver after partial hepatectomy is accelerated by triiodothyronine applied in three doses, two before and one immediately after liver resection. Triiodothyronine-treated animals already have higher cytochrome c oxidase activity before resection. The recovery of the tissue oxidative capacity after partial hepatectomy is more rapid in triiodothyronine-treated animals. These data indicate that hormonal activation of the liver regeneration process is involved.
authors.affiliation: Department of Physiology, Medical Faculty, Charles University, Hradec Králové, Czech Republic.
authors.forename: R
authors.initials: R
authors.lastname: Svátková
authors.forename: Z
authors.initials: Z
authors.lastname: Cervinková
authors.forename: M
authors.initials: M
authors.lastname: Kalous
authors.forename: H
authors.initials: H
authors.lastname: Rauchová
authors.forename: Z
authors.initials: Z
authors.lastname: Drahota
mesh_terms: D000818:Animals; D004247:DNA / Q000378:metabolism; D003576:Electron Transport Complex IV / Q000378:metabolism; D004734:Energy Metabolism; D006498:Hepatectomy; D008099:Liver / Q000166:cytology / Q000187:drug effects / Q000378:metabolism*; D008115:Liver Regeneration; D008297:Male; D010084:Oxidation-Reduction; D051381:Rats; D017208:Rats, Wistar; D014284:Triiodothyronine / Q000494:pharmacology*
chemical_list: D014284:Triiodothyronine; D004247:DNA; D003576:Electron Transport Complex IV