title: [Hospital results of angioplasty in multiple coronary vessel disease in 1990-1991 and 1994-1995. What conclusions should be drawn about the improvement of results with respect to the relevance of data of randomized trials comparing angioplasty and surgery].
abstract: The aim of this study was to determine whether advances in angioplasty techniques have improved results in multiple vessel coronary disease and to compare present results with those reported in randomised trials comparing angioplasty and surgery. The hospital results of two cohorts of multivessel coronary patients treated by angioplasty during two different periods were compared (group 1: 1990-1991. group 2: 1994-1995). The first period corresponded to the inclusion period of randomised trials comparing surgery and angioplasty. The patients in group 2 (n = 449) were older than those in group 1 (n = 424), had more triple vessel disease, more severe angina and more previous angioplasty attempts. Moreover, there were more cases of unfavourable lesions. Nevertheless, the clinical success rate was high in group 2 (92% vs 84%; p < 0.001) and the major complication rate (death, myocardial infarction or emergency bypass surgery) was lower (2.9% vs 6.1%; p = 0.02). The main technical difference between the two periods concerned the use of coronary stents (12% vs 8%; p < 0.001). The fact of being in group 2 was identified by multivariate analysis as an independent predictor for clinical success and a lower major complication rate. The authors conclude that, since the publication of randomised trials comparing angioplasty with coronary surgery, the hospital results of angioplasty have significantly improved. This should be taken into account in considering the clinical applications of the results of these trials.
authors.affiliation: Service de cardiologie, CHU de Nancy, hôpital de Brabois, Vandoeuvre-lès-Nancy.
authors.forename: M
authors.initials: M
authors.lastname: Angioï
authors.forename: N
authors.initials: N
authors.lastname: Danchin
authors.forename: L
authors.initials: L
authors.lastname: Jacquemin
authors.forename: P
authors.initials: P
authors.lastname: Houriez
authors.forename: J P
authors.initials: JP
authors.lastname: Preiss
authors.forename: M
authors.initials: M
authors.lastname: Cuillière
authors.forename: Y
authors.initials: Y
authors.lastname: Juillière
authors.forename: G
authors.initials: G
authors.lastname: Ethevenot
authors.forename: F
authors.initials: F
authors.lastname: Cherrier
mesh_terms: D000368:Aged; D000800:Angioplasty, Balloon / Q000639:trends; D006348:Cardiac Surgical Procedures / Q000639:trends; D003327:Coronary Disease / Q000628:therapy*; D005260:Female; D005602:France; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010043:Outcome and Process Assessment, Health Care; D016032:Randomized Controlled Trials as Topic