[Gonorrhea caused by fluoroquinolone resistant gonococci].
We describe a case of 4-fluoroquinolone resistant gonorrhoea where treatment failed on several occasions and where there may have been reinfections. Since 1995 peroral single dose 4-fluoroquinolones have been recommended as first preference treatment for uncomplicated gonorrhoea in Norway. However, Neisseria gonorrhoeae has a high ability to create resistance, and the emergence of 4-fluoroquinolone resistant strains is causing worldwide concern. An increasing number of 4-fluoroquinolone resistant gonococcal strains have also been observed in Norway, and the number of failures in the recommended treatment regime are increasing. It is proposed that 4-fluoroquinolone resistant strains be reported nationally.
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Avdeling for sos og hiv, Ullevål sykehus, Oslo.
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D000890:Anti-Infective Agents / Q000627:therapeutic use*; D016358:Contact Tracing; D004352:Drug Resistance, Microbial; D005260:Female; D024841:Fluoroquinolones; D006069:Gonorrhea / Q000188:drug therapy* / Q000276:immunology / Q000635:transmission; D006801:Humans; D008297:Male; D009344:Neisseria gonorrhoeae / Q000187:drug effects / Q000276:immunology; D009664:Norway
D000890:Anti-Infective Agents; D024841:Fluoroquinolones