title: A vitamin, anabolic, stimulant mixture. Is this form of medication advantageous for debilitated geriatric patients?
abstract: Of 32 underweight geriatric patients in a double-blind study, 24 were given a therapeutic mixture containing, per dose, 10 mg of methylphenidate, 2.5 mg of methandrostenolone, and a mixture of B vitamins; 8 patients were given placebo only. After eight weeks of this therapy, there was a significant weight gain in the treated patients. In some cases, this was associated with increased bromsulphalein retention. The number of patients who showed clinically evident increases in strength and vitality was no greater than in the control group. The results lend no support to the use of tonic mixtures instead of separate drugs.
authors.affiliation: Radioisotope Department, Methodist Hospital, Houston, Texas, USA.
authors.forename: P C
authors.initials: PC
authors.lastname: Johnson
authors.forename: J
authors.initials: J
authors.lastname: Shaw
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D045930:Anabolic Agents / Q000008:administration & dosage*; D001835:Body Weight / Q000187:drug effects; D000697:Central Nervous System Stimulants / Q000008:administration & dosage*; D003221:Confusion / Q000188:drug therapy; D004311:Double-Blind Method; D004338:Drug Combinations; D016330:Frail Elderly; D006801:Humans; D008696:Methandrostenolone / Q000008:administration & dosage*; D008774:Methylphenidate / Q000008:administration & dosage*; D008875:Middle Aged; D009735:Nursing Homes; D014815:Vitamins / Q000008:administration & dosage*
chemical_list: D045930:Anabolic Agents; D000697:Central Nervous System Stimulants; D004338:Drug Combinations; D014815:Vitamins; D008774:Methylphenidate; D008696:Methandrostenolone