Human parvovirus B19 infection resembling systemic lupus erythematosus.
A 39-year-old female visited our hospital because of morning stiffness, arthralgia, skin rash of the extremities and general fatigue. On examination, she also had a malar rash and an oral ulcer. Laboratory findings revealed that antinuclear antibodies were positive and complement component levels (C3, C4, CH50) were all low. Serology for human parvovirus B19 (HPV-B19) was positive for both immunoglobulin (Ig)M and IgG. Gradually, her symptoms improved and laboratory data returned to normal range without medications. This case suggests that HPV-B19 infection may be attributed to the pathogenesis of systemic lupus erythematosus.
Tanaka
A
A
Department of Nephrology, Saiseikai Nakatsu Hospital, Osaka.
Sugawara
A
A
Sawai
K
K
Kuwahara
T
T
D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D003937:Diagnosis, Differential; D016731:Erythema Infectiosum / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D008180:Lupus Erythematosus, Systemic / Q000175:diagnosis* / Q000821:virology; D016732:Parvovirus B19, Human / Q000302:isolation & purification
D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M