Xenopus cadherin-11 is expressed in different populations of migrating neural crest cells.
We cloned the Xenopus homologue of cadherin-11 and studied its spatiotemporal expression pattern during early development. The messenger RNA is present from the mid-gastrulation through embryo development. It is expressed in different neural crest cell populations, during their migration and differentiation. This pattern, unexpected for an adhesion molecule, reinforces the idea of novel functions for type II cadherins.
Vallin
J
J
Laboratoire de Morphogenèse Cellulaire et Progression Tumorale, UMR 144, CNRS/Institut Curie, 26 rue d'Ulm, 75248, Paris Cedex 05, France. jvallin@curie.fr
Girault
J M
JM
Thiery
J P
JP
Broders
F
F
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D015820:Cadherins / Q000235:genetics*; D018076:DNA, Complementary / Q000737:chemistry / Q000235:genetics; D004625:Embryo, Nonmammalian / Q000378:metabolism; D047108:Embryonic Development; D018507:Gene Expression Regulation, Developmental; D017403:In Situ Hybridization; D008969:Molecular Sequence Data; D009432:Neural Crest / Q000166:cytology / Q000254:growth & development / Q000378:metabolism*; D012333:RNA, Messenger / Q000032:analysis / Q000235:genetics; D017422:Sequence Analysis, DNA; D014981:Xenopus / Q000196:embryology / Q000235:genetics*
D015820:Cadherins; D018076:DNA, Complementary; D012333:RNA, Messenger; C086960:osteoblast cadherin