title: Cerebral blood flow measurements by magnetic resonance imaging bolus tracking: comparison with [(15)O]H2O positron emission tomography in humans.
abstract: In six young, healthy volunteers, a novel method to determine cerebral blood flow (CBF) using magnetic resonance (MR) bolus tracking was compared with [(15)O]H2O positron emission tomography (PET). The method yielded parametric CBF images with tissue contrast in good agreement with parametric PET CBF images. Introducing a common conversion factor, MR CBF values could be converted into absolute flow rates, allowing comparison of CBF values among normal subjects.
authors.affiliation: Department of Neuroradiology, Arhus University Hospital, Denmark.
authors.forename: L
authors.initials: L
authors.lastname: Ostergaard
authors.forename: P
authors.initials: P
authors.lastname: Johannsen
authors.forename: P
authors.initials: P
authors.lastname: Høst-Poulsen
authors.forename: P
authors.initials: P
authors.lastname: Vestergaard-Poulsen
authors.forename: H
authors.initials: H
authors.lastname: Asboe
authors.forename: A D
authors.initials: AD
authors.lastname: Gee
authors.forename: S B
authors.initials: SB
authors.lastname: Hansen
authors.forename: G E
authors.initials: GE
authors.lastname: Cold
authors.forename: A
authors.initials: A
authors.lastname: Gjedde
authors.forename: C
authors.initials: C
authors.lastname: Gyldensted
mesh_terms: D000328:Adult; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010104:Oxygen Radioisotopes; D012016:Reference Values; D014055:Tomography, Emission-Computed / Q000379:methods*; D014867:Water / Q000378:metabolism
chemical_list: D010104:Oxygen Radioisotopes; D014867:Water