[Neuropeptides in the treatment of sensorineural hypoacusis in children].
The examination of 250 children with neurosensory hypoacusis (NSH) demonstrated a 78% efficacy of endaural phonophoresis with dalargin (DPP) and transcranial electrostimulation (TCE) for improvement of acoustic function in the presence of positive ultrasound prognosis. Rheoencephalography and biochemical tests show that neuropeptides improve cerebral hemodynamics and normalize metabolism. Both DPP and TCE promote normalization of protein spectrum of the serum. In addition, TCE normalizes serum magnesium levels and its renal elimination, while DPP normalizes serum content of cholesterol.
Pudov
V I
VI
Grigor'eva
I F
IF
Atamanova
N V
NV
Boronev
S A
SA
D000293:Adolescent; D001921:Brain / Q000187:drug effects / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D003131:Combined Modality Therapy; D004341:Drug Evaluation; D004599:Electric Stimulation Therapy; D016308:Enkephalin, Leucine-2-Alanine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D006319:Hearing Loss, Sensorineural / Q000097:blood / Q000188:drug therapy* / Q000503:physiopathology; D006439:Hemodynamics / Q000187:drug effects; D006801:Humans; D009479:Neuropeptides / Q000008:administration & dosage*; D015612:Phonophoresis
D009479:Neuropeptides; D016308:Enkephalin, Leucine-2-Alanine; C040996:enkephalin-Leu, Ala(2)-Arg(6)-