Pupil-sparing third nerve palsy associated with sildenafil citrate (Viagra).
OBJECTIVE
To report unilateral pupil-sparing third nerve palsy after use of sildenafil citrate (Viagra).


METHODS
Case report.


RESULTS
A 56-year-old man with a history of tobacco abuse was treated for erectile dysfunction. Viagra, 50 mg, was taken once without adverse effect. Three weeks later, the patient took a second dose of Viagra (50 mg); 36 hours later he experienced a complete pupil-sparing third nerve palsy. Erythrocyte sedimentation rate, blood glucose level, magnetic resonance imaging, and magnetic resonance angiography were normal.


CONCLUSIONS
In a patient with microvascular disease, use of sildenafil may be associated with pupil-sparing third nerve palsy.
Donahue
S P
SP
Department of Ophthalmology and Visual Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Taylor
R J
RJ
D001786:Blood Glucose / Q000032:analysis; D001799:Blood Sedimentation; D004791:Enzyme Inhibitors / Q000009:adverse effects*; D006801:Humans; D007498:Iris / Q000294:innervation*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015840:Oculomotor Nerve Diseases / Q000139:chemically induced*; D010879:Piperazines / Q000009:adverse effects*; D011680:Pupil; D011687:Purines; D000068677:Sildenafil Citrate; D013450:Sulfones
D001786:Blood Glucose; D004791:Enzyme Inhibitors; D010879:Piperazines; D011687:Purines; D013450:Sulfones; D000068677:Sildenafil Citrate