title: Risk factors in the surgical management of perforated duodeno-pyloric ulcer.
abstract: The election of the treatment in the pyloric-duodenal perforations pursues a double objective: to reduce the operative mortality and to reduce the risk of ulcerous relapse in the long run. The authors carry out a retrospective study of 100 pyloric-duodenal perforations treated in 12 years. Three risk factors of immediate mortality are demonstrated: the age, 70 years or older; elapsed time, equal or superior to 24 hours and the existence of a situation of preoperative hemodynamic shock. The global mortality of the series was of 12% and the index of relapses of 12%. The authors outline a therapeutic management in which the election of the treatment was modulated for the factors of mortality risk. Thus, the presence of one of these factors must lead to the accomplishment of single treatment in treating only the perforation. The absence of risk factors must lead to accomplish a definitive treatment through the resection or the suture of the perforation followed by any type of vagotomy and eventually a drainage operation. The results obtained with Taylor's vagotomy, as well as with laparoscopic methods have not yet been validated although, probably, in a near future they will be integrated in the first management of pyloric-duodenal perforations.
authors.affiliation: Service of Surgical, University Clinical Hospital, Zaragoza, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Deus Fombellida
authors.forename: I
authors.initials: I
authors.lastname: Gil Romea
authors.forename: M J
authors.initials: MJ
authors.lastname: Moreno Mirallas
authors.forename: A
authors.initials: A
authors.lastname: Urieta Carpi
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D004381:Duodenal Ulcer / Q000150:complications* / Q000601:surgery; D004630:Emergencies; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D010439:Peptic Ulcer Perforation / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D011706:Pyloric Antrum / Q000601:surgery; D012307:Risk Factors; D014628:Vagotomy