Use of remifentanil in infants.
We describe the use of remifentanil in three infants with complex medical issues (hepatic failure, cyanotic heart disease and renal compromise). The short duration of opioid effect even after a long period of drug infusion (18 h) suggests this drug may be useful in some infants. Continued study is warranted.
Eck
J B
JB
Department of Anesthesiology, University of Washington School of Medicine, Seattle, USA.
Lynn
A M
AM
D000701:Analgesics, Opioid / Q000627:therapeutic use*; D004314:Down Syndrome / Q000503:physiopathology; D004374:Ductus Arteriosus, Patent / Q000150:complications / Q000503:physiopathology / Q000601:surgery; D004694:Endocardial Cushion Defects / Q000150:complications / Q000503:physiopathology; D006333:Heart Failure / Q000150:complications / Q000503:physiopathology; D006439:Hemodynamics; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007442:Intubation, Intratracheal; D007674:Kidney Diseases / Q000150:complications / Q000503:physiopathology; D017093:Liver Failure / Q000150:complications / Q000503:physiopathology; D008297:Male; D010880:Piperidines / Q000627:therapeutic use*; D000077208:Remifentanil; D012415:Rubinstein-Taybi Syndrome / Q000150:complications / Q000503:physiopathology
D000701:Analgesics, Opioid; D010880:Piperidines; D000077208:Remifentanil