title: [Chronic depigmentation due to positive patch tests for methacryate derivatives].
abstract: BACKGROUND
  Many chemical products are known to induce depigmentation. This phenomenon was never reported with methacrylates which are components of acrylic resine.
  
  
  METHODS
  A female patient with artificial nails developed contact dermatitis. Localized depigmentation at the site of positive patch tests to methacrylates derivatives was observed.
  
  
  CONCLUSIONS
  The chemical substance could have a direct influence either by its toxic effect or by the induced inflammatory reaction.
authors.affiliation: Service de Dermatologie, Hôpital Robert Debré, Reims.
authors.forename: V
authors.initials: V
authors.lastname: Casse
authors.forename: V
authors.initials: V
authors.lastname: Salmon-Ehr
authors.forename: C
authors.initials: C
authors.lastname: Mohn
authors.forename: B
authors.initials: B
authors.lastname: Kalis
mesh_terms: D000328:Adult; D002484:Cementation / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D017496:Hypopigmentation / Q000139:chemically induced*; D008689:Methacrylates / Q000009:adverse effects*; D009259:Nail Biting / Q000628:therapy; D010328:Patch Tests / Q000009:adverse effects*; D019919:Prosthesis Implantation / Q000009:adverse effects
chemical_list: D008689:Methacrylates