title: Vascular interventions during post-chemotherapy retroperitoneal lymph-node dissection for metastatic testis cancer.
abstract: OBJECTIVE
  Complete excision of nodal masses during post-chemotherapy retroperitoneal lymph-node dissection (RPLND) for metastatic non-seminomatous germ-cell tumours (NSGCT) of the testis often requires vascular surgical intervention. We report our experience of vascular interventions and complications in a large series of men undergoing postchemotherapy RPLND.
  
  
  METHODS
  A retrospective review of vascular interventions during post-chemotherapy RPLND in 98 patients was undertaken (103 procedures).
  
  
  RESULTS
  Macroscopic tumour clearance was complete in 95/98 men (97%). Vascular intervention was required in all cases. Major complications included acute tubular necrosis in one patient who had undergone left nephrectomy and extensive dissection around the right renal artery, progressive atrophy of the ipsilateral kidney in three men and a colonic stricture and associated colocutaneous fistula in one patient after division of the inferior mesenteric artery. Iliac and femoral venous thrombosis developed in both patients in whom the inferior vena cava (IVC) was excised and in one patient after partial IVC excision. Eight of the 98 patients have died. No late vascular complications have occurred to date.
  
  
  CONCLUSIONS
  Complete tumour clearance can be achieved in most post-chemotherapy RPLNDs but invariably involves vascular intervention. Metastatic NSGCT should be treated by surgeons with the ability to undertake the vascular procedures required.
authors.affiliation: Department of Urology, Charing Cross Hospital, London. UK.
authors.forename: T J
authors.initials: TJ
authors.lastname: Christmas
authors.forename: G L
authors.initials: GL
authors.lastname: Smith
authors.forename: R
authors.initials: R
authors.lastname: Kooner
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D018237:Germinoma / Q000556:secondary / Q000601:surgery*; D006801:Humans; D008197:Lymph Node Excision / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012186:Retroperitoneal Neoplasms / Q000556:secondary / Q000601:surgery*; D012189:Retrospective Studies; D013736:Testicular Neoplasms / Q000473:pathology / Q000601:surgery*; D014656:Vascular Surgical Procedures