Eletefine, a stephaoxocane alkaloid from cissampelos glaberrima
A novel isoquinoline alkaloid bearing an oxocane ring (stephaoxocane type (Kashiwaba, N.; Morooka, S.; Kimura, M.; Ono, M.; Toda, J.; Suzuki, H.; Sano, T. J. Nat. Prod. 1996, 59, 803)), has been isolated from the roots of Cissampelos glaberrima. This compound was given the trivial name eletefine (1) and its structure assigned on the basis of spectroscopic data and conversion to the corresponding ketone (2).
da-Cunha
EVL
Laboratorio de Tecnologia Farmaceutica, Universidade Federal da Paraiba, Cx. Postal 5009, 58051-970, Joao Pessoa, PB, Brazil, Universidade Estadual do Norte Fluminense, 28015-620, Campos, RJ, Brazil, and Phytochemistry Research Laboratori.
Cornelio
ML
Barbosa-Filho
JM
Braz-Filho
R
Gray
AI