Ptosis in Waldenström's macroglobulinemia.
OBJECTIVE
To report a case of chronic, progressive unilateral blepharoptosis in a 73-year-old woman with Waldenström's macroglobulinemia.


METHODS
Case report. A biopsy was performed on a thickened and indurated tarsal plate that we believed had resulted in mechanical blepharoptosis.


RESULTS
Histologic and immunohistochemistry studies of the biopsy specimen demonstrated a lymphoplasmacytoid cell infiltrate with monoclonal antibodies consistent with Waldenström's macroglobulinemia.


CONCLUSIONS
Involvement of the tarsal conjunctiva and tarsus in Waldenstrom's macroglobulinemia is a newly recognized cause of eyelid thickening and ptosis.
Klapper
S R
SR
University of Ottawa Eye Institute, Ontario, Canada.
Jordan
D R
DR
Pelletier
C
C
Brownstein
S
S
Punja
K
K
D000368:Aged; D001763:Blepharoptosis / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D002908:Chronic Disease; D018450:Disease Progression; D005143:Eyelids / Q000473:pathology / Q000503:physiopathology; D005260:Female; D006801:Humans; D008258:Waldenstrom Macroglobulinemia / Q000150:complications* / Q000175:diagnosis