Demyelinating inflammatory neuropathies, including Guillain-Barré syndrome.
The highly complex and multiple mechanisms responsible for the development of demyelinating neuropathies are reviewed, in particular Guillain-Barré syndrome and its variant Miller Fisher syndrome, chronic inflammatory demyelinating neuropathy, multifocal motor neuropathy, anti-myelin-associated glycoprotein neuropathy, as well as experimental models. Recent investigations into the role of auto antibodies against myelin proteins, or glycolipids have given insights into the pathogenesis of demyelinating inflammatory neuropathies.
Steck
A J
AJ
Department of Neurology, University of Basel, Switzerland. steck@ubaclu.unibas.ch
Schaeren-Wiemers
N
N
Hartung
H P
HP
D001327:Autoimmune Diseases / Q000276:immunology; D002908:Chronic Disease; D003711:Demyelinating Diseases / Q000276:immunology / Q000503:physiopathology*; D006801:Humans; D019846:Miller Fisher Syndrome / Q000276:immunology; D016472:Motor Neuron Disease / Q000276:immunology; D009186:Myelin Sheath / Q000276:immunology; D009443:Neuritis / Q000276:immunology; D011129:Polyradiculoneuropathy / Q000276:immunology / Q000503:physiopathology*