Nitro-polycyclic aromatic hydrocarbon contents of fumes from heated cooking oils and prevention of mutagenicity by catechin.
According to earlier studies, fumes from cooking oils were found to be mutagenic and several polycyclic aromatic hydrocarbons (PAHs), (benzo(a)pyrene (B(a)P), benz(a)antracene (B(a)A), and dibenz(a,h)anthracene (DB(ah)A)) were identified. Fume samples from three different commercial cooking oils frequently used in Taiwan were collected and nitro-polycyclic aromatic hydrocarbons (NPAHs) were extracted from the samples and identified by HPLC chromatography. Extracts from three cooking oil fumes contained 1-nitropyrene (1-NP) and 1,3-dinitropyrene (1,3-DNP). Concentrations of 1-NP and 1,3-DNP were 1.1 +/- 0.1 and 0.9 +/- 0.1 micrograms/m3 in fumes from lard oil, 2.9 +/- 0.3 and 3.4 +/- 0.2 micrograms/m3 in soybean oil, 1.5 +/- 0.1 and 0.4 +/- 0.1 micrograms/m3 in peanut oil, respectively. The preventive effect of three natural antioxidants (gamma-tocopherol (TOC), lecithin (LEC), and catechin (CAT)) for the reduction of mutagenicity and amounts of PAHs and NPAHs of fumes from cooking oils were evaluated. Mutagenicity of cooking oil fumes occurred, and the concentration of B(a)P were significantly reduced (p < 0.05), by adding CAT into cooking oils before heating. B(a)A, DB(ah)A, and two NPAHs were not detected when the concentration of CAT was 500 ppm in all three cooking oil fumes. These results indicate that fumes of cooking oils contained PAHs and NPAHs that may be a risk factor for lung cancer among cooks and the carcinogens could be reduced by adding the natural antioxidant, catechin.
Wu
P F
PF
Department of Industrial Safety and Hygiene, Ta-Jen Junior College of Pharmacy, Ping-Tung, Taiwan.
Chiang
T A
TA
Wang
L F
LF
Chang
C S
CS
Ko
Y C
YC
D016587:Antimutagenic Agents / Q000494:pharmacology; D000975:Antioxidants / Q000494:pharmacology; D010367:Arachis; D002392:Catechin / Q000494:pharmacology*; D004041:Dietary Fats; D005260:Female; D006358:Hot Temperature; D006801:Humans; D008175:Lung Neoplasms / Q000209:etiology / Q000517:prevention & control; D009152:Mutagenicity Tests; D009153:Mutagens / Q000032:analysis* / Q000633:toxicity*; D009821:Oils / Q000032:analysis* / Q000633:toxicity; D000074241:Peanut Oil; D010938:Plant Oils / Q000032:analysis* / Q000633:toxicity*; D011084:Polycyclic Aromatic Hydrocarbons / Q000032:analysis* / Q000633:toxicity*; D012486:Salmonella typhimurium / Q000187:drug effects / Q000235:genetics; D013024:Soybean Oil / Q000032:analysis / Q000633:toxicity; D013624:Taiwan
D016587:Antimutagenic Agents; D000975:Antioxidants; D004041:Dietary Fats; D009153:Mutagens; D009821:Oils; D000074241:Peanut Oil; D010938:Plant Oils; D011084:Polycyclic Aromatic Hydrocarbons; D013024:Soybean Oil; D002392:Catechin; C029310:lard