Molecular cloning and sequence determination of a novel aspartic proteinase from Antarctic fish.
In the present report, we describe a novel aspartic proteinase from the liver of two Antarctic fish species. The nucleotide sequences of the cDNA obtained from the two fishes show 90% identity with each other but only 58% identity with aspartic proteinases from other sources. Sequence analysis shows features for the Antarctic enzymes which are not present in related enzymes of other organisms.
Capasso
C
C
Institute of Protein Biochemistry and Enzymology, via Marconi, 10, I-80125 Naples, Italy.
Riggio
M
M
Scudiero
R
R
Carginale
V
V
di Prisco
G
G
Kay
J
J
Kille
P
P
Parisi
E
E
D000595:Amino Acid Sequence; D000818:Animals; D000864:Antarctic Regions; D016282:Aspartic Acid Endopeptidases / Q000737:chemistry*; D001483:Base Sequence; D003001:Cloning, Molecular; D005399:Fishes; D008099:Liver / Q000201:enzymology; D008969:Molecular Sequence Data; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
D016282:Aspartic Acid Endopeptidases