No association between tacrine transaminitis and the glutathione transferase theta genotype in patients with Alzheimer's disease.
De Sousa
M
M
Department of Pharmacology and Therapeutics, The University of Liverpool, UK.
Pirmohamed
M
M
Kitteringham
N R
NR
Woolf
T
T
Park
B K
BK
D000544:Alzheimer Disease / Q000188:drug therapy / Q000201:enzymology* / Q000235:genetics; D056486:Chemical and Drug Induced Liver Injury; D002800:Cholinesterase Inhibitors / Q000009:adverse effects* / Q000627:therapeutic use; D017931:DNA Primers; D005787:Gene Frequency; D005838:Genotype; D005982:Glutathione Transferase / Q000235:genetics*; D006801:Humans; D008107:Liver Diseases / Q000097:blood; D013619:Tacrine / Q000009:adverse effects* / Q000627:therapeutic use; D000637:Transaminases / Q000097:blood*
D002800:Cholinesterase Inhibitors; D017931:DNA Primers; D013619:Tacrine; D005982:Glutathione Transferase; D000637:Transaminases