[Effect of a bioactive food supplement from selenium enriched baker's yeast autolysate on the status of the intestinal barrier in rats with anaphylaxis].
Rat's intestinal barrier permeability disturbed in consequence of intestinal anaphylaxis reaction was almost completely normalized in animals fed with baker's yeast autolysate "Vitasil" enriched with selenium on a level of 3 mg Se/day during 29 days. These rats showed in comparison to Se-unsupplemented animals a significant elevation of Se level in red blood cells and plasma together with a decrease of intestinal mucosal TCA-soluble thiol compounds. Urinary Se excretion was significantly elevated in comparison to unsensitized rats both in Se-supplemented and unsupplemented animals with anaphylaxis. It's concluded that "Se-Vitasil" may be successfully used in antioxidative therapy of food allergy, malabsorption, inflammatory bowel diseases and intestinal infection.
Golubkina
N A
NA
Gmoshinskiĭ
I V
IV
Zorin
S N
SN
Danilina
L L
LL
Chistiakov
A V
AV
Mazo
V K
VK
D000707:Anaphylaxis / Q000178:diet therapy*; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001329:Autolysis; D002199:Capillary Permeability; D005527:Food, Fortified; D007422:Intestines / Q000098:blood supply*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D012440:Saccharomyces; D012643:Selenium / Q000494:pharmacology*
D000975:Antioxidants; D012643:Selenium