title: [Normal term delivery after adrenalectomy for Cushing syndrome in a pregnant patient--a case report].
abstract: This is a case of a 29-year-old female. She visited our hospital with the chief complaint of swelling of the legs and abdominal bloating at the 10th week of pregnancy. Edema and central obesity were observed in the lower extremities. Hematological and biochemical tests revealed hypokalemia. Gynecologically, she was normal. Elevated blood cortisol levels were identified on the hormonal tests, which suggested the existence of Cushing's syndrome. Ultrasound revealed the presence of a tumor in the left adrenal gland, and she was referred to our department for surgery. On September 13, 1994, left adrenalectomy was performed in a right lateral position under inhalation anesthesia and epidural anesthesia. Adjuvand steroid therapy was initiated during surgery and the blood cortisol levels were normalized within 2 months. She delivered a baby girl weighing 2,722 g at the 40th week of pregnancy via a normal transvaginal delivery. Pregnancy rarely occurs in patients with Cushing's syndrome. We think she was the first case in Japan who had normal 40th week transvaginal delivery after adrenalectomy during pregnancy. We present a description of our case here with reference to the relevant literature.
authors.affiliation: First Department of Urology, Toho University School of Medicine.
authors.forename: K
authors.initials: K
authors.lastname: Ueda
authors.forename: K
authors.initials: K
authors.lastname: Nakajima
authors.forename: E
authors.initials: E
authors.lastname: Nozawa
authors.forename: D
authors.initials: D
authors.lastname: Nishimi
authors.forename: K
authors.initials: K
authors.lastname: Nagao
authors.forename: H
authors.initials: H
authors.lastname: Hara
authors.forename: T
authors.initials: T
authors.lastname: Kuwabara
authors.forename: K
authors.initials: K
authors.lastname: Kuroda
authors.forename: M
authors.initials: M
authors.lastname: Takanami
authors.forename: N
authors.initials: N
authors.lastname: Ishii
authors.forename: K
authors.initials: K
authors.lastname: Miura
authors.forename: M
authors.initials: M
authors.lastname: Shirai
mesh_terms: D000315:Adrenalectomy; D000328:Adult; D003480:Cushing Syndrome / Q000601:surgery*; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D007743:Labor, Obstetric; D011247:Pregnancy; D011248:Pregnancy Complications / Q000601:surgery*