Experimental infection of dogs with the nasal mite Pneumonyssoides caninum.
A successful experimental transmission of the canine nasal mite, Pneumonyssoides caninum, is described. Some 11 weeks after repeated systemic ivermectin treatment, four Beagles were inoculated via the right nostril with 20 P. caninum mites of different sexes and life stages, obtained at the necropsy of an infected dog. The inoculated dogs and a matching uninoculated control were observed for clinical signs for 14 weeks and then euthanised. Vague upper respiratory signs and a transient minor increase in the number of eosinophils in peripheral blood were recorded in the inoculated dogs. At necropsy 4-12 P. caninum mites were found in the nasal cavities and sinuses of the inoculated dogs, but none in the control. In three out of the four infected dogs mites were found in both the right and left nasal cavities and sinuses of the skull. Since in no case more mites than the number used for inoculation were detected it is not clear if the mites managed to reproduce in the dogs. Inflammatory lesions were seen most consistently in the olfactory mucosa, respiratory mucosa and tonsils, and growth of opportunistic bacteria was observed in the tonsils of the infected dogs. The inflammatory lesions seen in the olfactory mucosa may explain why dogs infected with P. caninum sometimes appear to suffer from impaired scenting ability.
Gunnarsson
L
L
Department of Parasitology, National Veterinary Institute (SVA) and Swedish University of Agricultural Sciences (SLU), Uppsala. lotta.gunnarsson@sva.se
Zakrisson
G
G
Lilliehook
I
I
Christensson
D
D
Rehbinder
C
C
Uggla
A
A
D000818:Animals; D001419:Bacteria / Q000302:isolation & purification; D004283:Dog Diseases / Q000097:blood / Q000473:pathology; D004285:Dogs; D005260:Female; D006454:Hemoglobins / Q000032:analysis; D007958:Leukocyte Count / Q000662:veterinary; D008297:Male; D008924:Mite Infestations / Q000097:blood / Q000473:pathology / Q000662:veterinary*; D008925:Mites / Q000254:growth & development; D009296:Nasal Cavity / Q000469:parasitology / Q000473:pathology; D009668:Nose Diseases / Q000097:blood / Q000473:pathology / Q000662:veterinary*; D009831:Olfactory Mucosa / Q000382:microbiology / Q000473:pathology; D014066:Palatine Tonsil / Q000382:microbiology / Q000473:pathology; D010256:Paranasal Sinuses / Q000469:parasitology / Q000473:pathology
D006454:Hemoglobins