Fetal tissue transplantation [correction of transplanation] in Parkinson's disease.
Since the first successful attempts in 1990, human embryonic tissue transplantation has attracted the attention of multiple investigators and clinicians as a serious candidate therapy for Parkinson's disease. Although over two hundred patients have undergone the procedure, multiple issues and questions remain unresolved. We will address this topic emphasizing the recent advances in the technical aspects of the transplantation procedure in light of the limited animal and clinical experience available.
Tabbal
S
S
Department of Neurology, College of Physician and Surgeons of Columbia University New York, New York 10032, USA.
Fahn
S
S
Frucht
S
S
D002470:Cell Survival; D002986:Clinical Trials as Topic; D016332:Fetal Tissue Transplantation; D005818:Genetic Engineering; D006085:Graft Survival; D006801:Humans; D007165:Immunosuppression Therapy; D010300:Parkinson Disease / Q000601:surgery*; D014019:Tissue Donors