Pathobiology and clinical significance of molecular genetic findings in childhood tumors.
Molecular genetic determinants of malignant diseases in children are providing insights into the mechanisms of malignancies. These findings have improved diagnosis, treatment, and prognosis.
Rubnitz
J E
JE
Department of Pediatrics, University of Tennessee, College of Medicine, Memphis, USA.
Downing
J R
JR
Crist
W M
WM
D002648:Child; D016147:Genes, Tumor Suppressor / Q000235:genetics; D006801:Humans; D007951:Leukemia, Myeloid / Q000175:diagnosis / Q000235:genetics; D008223:Lymphoma / Q000175:diagnosis / Q000235:genetics; D009369:Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D009447:Neuroblastoma / Q000175:diagnosis / Q000235:genetics; D009857:Oncogenes / Q000235:genetics; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis / Q000235:genetics