title: Catch-up growth occurs after renal transplantation in children of pubertal age.
abstract: OBJECTIVE
  Assessment of growth after renal transplantation in children of pubertal age by analyzing the annual increment in height standard deviation score (Ht SDS) in all girls > or =10 years and boys > or =11 years of age at the time of transplantation until latest follow-up (minimum 2 years).
  
  
  METHODS
  A total of 59 grafts were placed in 54 recipients (30 boys) between December 1984 and January 1995. Mean (range) age at transplantation was 13.6 years (10.1 to 17.7 years). Fifty-one percent had congenital renal disease, 36% acquired renal disease, and 13% had hereditary nephropathies. Eighty-seven percent were first grafts; of these, 29% were performed pre-emptively, and 23% were from living related donors.
  
  
  RESULTS
  Mean (SD) Ht SDS at transplantation was -1.8 (0.2) and increased significantly thereafter, such that it was -1.6 (0.2) at 1 year, n = 52; -1.5 (0.2) at 2 years, n = 47; -1.0 (0.2) at 3 years, n = 27; -0.7 (0.3) at 4 years, n = 19; and -0.6 (0.3), n = 13, at 5 years after transplantation (analysis of variance, P < .001). The greatest improvement in Ht SDS in the first year was seen in children with the highest glomerular filtration rate (r = 0.429, P = .002) and in those who were shortest at the time of transplantation (r = -0.356, P = .009).
  
  
  CONCLUSIONS
  Catch-up growth occurs in children receiving renal transplants during the expected time of puberty.
authors.affiliation: Institute of Child Health, University of London, United Kingdom.
authors.forename: H
authors.initials: H
authors.lastname: Maxwell
authors.forename: D
authors.initials: D
authors.lastname: Haffner
authors.forename: L
authors.initials: L
authors.lastname: Rees
mesh_terms: D000293:Adolescent; D000704:Analysis of Variance; D001827:Body Height / Q000502:physiology; D002102:Cadaver; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D005544:Forecasting; D005919:Glomerular Filtration Rate / Q000502:physiology; D006128:Growth / Q000502:physiology*; D006801:Humans; D007674:Kidney Diseases / Q000151:congenital / Q000235:genetics / Q000601:surgery; D016030:Kidney Transplantation / Q000502:physiology*; D019520:Living Donors; D008297:Male; D011446:Prospective Studies; D011627:Puberty / Q000502:physiology*; D012189:Retrospective Studies