False family history of breast cancer in the family cancer clinic.
OBJECTIVE
Awareness of hereditary breast and ovarian cancer in both the general public and the medical profession is increasing. Individuals who may be at risk on the basis of a family history are requesting risk determination and appropriate management in a variety of settings. Risk determination relies largely on pedigree analysis and epidemiological data.


METHODS
We describe five individuals presenting in the family cancer or genetic counselling clinic where a factitious family or personal history led to erroneous risk estimation. Common factors in these families are a history of benign breast disease, poor communication within families, long survival with early onset or bilateral disease, a lack of detailed knowledge of the illness and treatment in close relatives and inconsistencies in the history in repeated consultations.
Kerr
B
B
Department of Medical Genetics, St Mary's Hospital, Manchester.
Foulkes
W D
WD
Cade
D
D
Hadfield
L
L
Hopwood
P
P
Serruya
C
C
Hoare
E
E
Narod
S A
SA
Evans
D G
DG
D000328:Adult; D001943:Breast Neoplasms / Q000235:genetics*; D005195:Family Relations; D005260:Female; D005817:Genetic Counseling / Q000379:methods; D006801:Humans; D010375:Pedigree; D012306:Risk; D006113:United Kingdom; D014481:United States