title: Primary adenocarcinoma of the urethra with metastasis to the glans penis: successful treatment with chemotherapy and radiation therapy.
abstract: Primary carcinoma of the male urethra accounts for less than 1% of malignancies in males. A 54-year-old man with primary adenocarcinoma of the urethra with metastasis to the glans penis and lymphadenopathy in the right groin was treated successfully by combined chemotherapy (5-fluorouracil and cis-platinum) and external beam radiotherapy (total dose of 75 Gy). Short-term remission using multimodal approach with penile preservation was achieved in the present case.
authors.affiliation: Department of Urology, Wayne State University School of Medicine and Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, USA.
authors.forename: M V
authors.initials: MV
authors.lastname: Tefilli
authors.forename: E L
authors.initials: EL
authors.lastname: Gheiler
authors.forename: B
authors.initials: B
authors.lastname: Shekarriz
authors.forename: J G
authors.initials: JG
authors.lastname: de Oliveira
authors.forename: R
authors.initials: R
authors.lastname: Tiguert
authors.forename: D
authors.initials: D
authors.lastname: Grignon
authors.forename: J E
authors.initials: JE
authors.lastname: Pontes
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary* / Q000628:therapy*; D003131:Combined Modality Therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010412:Penile Neoplasms / Q000556:secondary* / Q000628:therapy*; D012074:Remission Induction; D014523:Urethral Neoplasms / Q000473:pathology* / Q000628:therapy*