[Effect of preoperative administration of Lugol's solution on thyroid blood flow in hyperthyroidism].
A study of 50 patients with hyperthyroidism was conducted to evaluate the effect of preoperative administration of Lugol's iodine solution on thyroid blood flow. Highly significant reductions in diameter, time-averaged velocity, and volume flow of the superior thyroid artery were demonstrated after administration of Lugol's solution. The Duplex ultrasound scanning used in this study is a noninvasive, inexpensive, accurate, and reproducible technique suitable for analysis of thyroid blood flow in hyperthyroidism. On the basis of current ultrasonographic results and low postoperative morbidity in patients, Lugol's solution is well tolerated and may be recommended for use before thyroidectomy, especially for diffuse toxic goiters and Graves disease.
Rodier
J F
JF
Département de Chirurgie Oncologique, Centre Régional de Lutte Contre le Cancer Paul-Strauss, Strasbourg.
Janser
J C
JC
Petit
H
H
Schneegans
O
O
Ott
G
G
Kaissling
A
A
Grob
J C
JC
Velten
M
M
D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000601:surgery*; D007454:Iodides / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011292:Premedication; D012039:Regional Blood Flow / Q000187:drug effects; D013961:Thyroid Gland / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000187:drug effects; D013965:Thyroidectomy; D014463:Ultrasonography
D007454:Iodides; C010389:Lugol's solution