title: Computer analysis system of blood oxygen saturation in an animal hypoxia model.
abstract: An experimental animal hypoxia model has been developed. It consists of two sensors (an in vitro and in vivo model), an experimental device and a computer signal processing system. This method can easily be applied to determine and analyse blood oxygen saturation at various hypoxia levels. It can also be used to evaluate the accuracy of pulse oximetry over a wide range of oxyhemoglobin desaturation levels. The DC and AC components of recorded red and infra-red signals, the dual-wavelength ratio R12 and the reading of a pulse oximeter (SpO2) can be automatically calculated and displayed on a computer screen. Preliminary results of the animal hypoxia test indicate that the measurements made by the instrument correlate well with the oxygen saturation readings of the automatic blood gas analyser AVL945. The computer analysis system is suitable for repeated estimations in the animal model.
authors.affiliation: Department of Biological Engineering, Huazhong University of Science & Technology, Wuhan, Peoples Republic of China. yxyang@blue.hust.edu.cn
authors.forename: Y X
authors.initials: YX
authors.lastname: Yang
authors.forename: B S
authors.initials: BS
authors.lastname: Xie
authors.forename: Z X
authors.initials: ZX
authors.lastname: Zhou
authors.forename: J N
authors.initials: JN
authors.lastname: Liu
authors.forename: Y Y
authors.initials: YY
authors.lastname: Xue
authors.forename: G L
authors.initials: GL
authors.lastname: Lv
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D001330:Electronic Data Processing; D000860:Hypoxia / Q000097:blood*; D010092:Oximetry; D011817:Rabbits; D012680:Sensitivity and Specificity