title: Adrenal cortical epithelial cysts in two saddleback tamarins (Saguinus fuscicollis).
abstract: Adrenal cysts of epithelial origin were found incidentally in the adrenal cortical tissues of two adult female saddleback tamarins. In one case, a small cluster of minor cysts was located at the cortico-medullary border. The cysts were filled with a periodic acid-Schiff (PAS)-positive, amorphous substance and lined by a cuboidal PAS-negative epithelium, which resembled morphologically the ascending Henle's loops of the kidney. These microcysts were thought to be mesonephric remnants. In the second case, two large cysts of 1 to 3 mm diameter extended throughout the entire cortex. The cysts were filled by a watery, PAS-negative fluid and lined by a bi- to multi-layered, cytokeratin-positive epithelium. The basal epithelial layer consisted of cuboidal cells, which became cylindrical to drop-like in appearance towards the cyst lumen. The cysts closely resembled mesothelium-derived adrenal cysts in man. This is the first report of adrenal cysts in non-human primates.
authors.affiliation: Deutsches Primatenzentrum, Göttingen, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Brack
mesh_terms: D000302:Adrenal Cortex / Q000473:pathology*; D000307:Adrenal Gland Diseases / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D003560:Cysts / Q000473:pathology / Q000662:veterinary*; D004848:Epithelium / Q000473:pathology; D005260:Female; D008992:Monkey Diseases / Q000473:pathology*; D010503:Periodic Acid-Schiff Reaction / Q000662:veterinary; D012452:Saguinus