title: Using computer databases to predict and avoid drug-drug interactions in the cancer patient requiring psychotropics.
abstract: Psychotropic drug interactions with medical prescriptions is an essential knowledge base for the practicing oncologist as well as the psychiatrist. This paper describes a method to identify, understand, and develop a conceptual framework to codify psychotropic-medical drug interactions; a systemic approach for updating this key database, and a software system to assist in the management of this ever unfolding sphere of knowledge; and, a set of instruments to provide ongoing developments in this important area. Since many of the trials either for oncological medications or psychotropic drugs did not include studies comparing these two domains, their interactions often only become known with their utilization and subsequent reporting.
authors.affiliation: Mount Sinai Medical Center, Department of Psychiatry, New York, NY 10029, USA.
authors.forename: J J
authors.initials: JJ
authors.lastname: Strain
authors.forename: G
authors.initials: G
authors.lastname: Caliendo
authors.forename: C
authors.initials: C
authors.lastname: Himelein
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems; D016208:Databases, Factual; D004347:Drug Interactions; D005544:Forecasting; D006801:Humans; D016239:MEDLINE; D001523:Mental Disorders / Q000188:drug therapy; D009369:Neoplasms / Q000150:complications / Q000523:psychology*; D011619:Psychotropic Drugs / Q000009:adverse effects* / Q000627:therapeutic use; D012984:Software
chemical_list: D011619:Psychotropic Drugs