Killing of Pseudomonas pseudomallei by polymorphonuclear leukocytes and peritoneal macrophages from chicken, sheep, swine and rabbits.
Differences in the kinetics of Pseudomonas pseudomallei killing by peritoneal macrophages (PM) and polymorphonuclear leucocytes (PMNL) from chickens, sheep, swine and rabbits were found. P. pseudomallei was rapidly killed by porcine PM and PMNL. However the bacterial killing by ovine and lapine PM and PMNL proceeded at a slower rate. In contrast, chicken PM and PMNL ingested and killed the lowest number of P. pseudomallei bacteria. The differences in the bactericidal activity of PM and PMNL from different animal species correlated with the level of their acid phosphatase and glycolytic activity.
Markova
N
N
Institute of Microbiology, Bulgarian Academy of Sciences, Sofia, Bulgaria.
Kussovski
V
V
Radoucheva
T
T
D000135:Acid Phosphatase / Q000378:metabolism; D000818:Animals; D000829:Animals, Domestic / Q000276:immunology*; D016957:Burkholderia pseudomallei / Q000276:immunology*; D002645:Chickens / Q000276:immunology; D006019:Glycolysis; D017737:Macrophages, Peritoneal / Q000201:enzymology / Q000276:immunology* / Q000378:metabolism; D009504:Neutrophils / Q000201:enzymology / Q000276:immunology* / Q000378:metabolism; D010587:Phagocytosis; D011817:Rabbits / Q000276:immunology; D012756:Sheep / Q000276:immunology; D013045:Species Specificity; D013552:Swine / Q000276:immunology
D000135:Acid Phosphatase