title: Novel pattern of Brachyury gene expression in hemichordate embryos.
abstract: Together with echinoderms and chordates, hemichordates constitute the third major group of the deuterostomes, which share a number of common developmental features. The Brachyury gene is responsible for the formation of notochord, the most defining feature of chordates. Therefore, isolation and characterization of the hemichordate homolog of Brachyury is key to understand the origin and evolution of chordates. Here we show that the hemichordate Brachyury gene (PfBra) is expressed in two regions of the gastrula and young tornaria larva, the archenteron invagination region and the stomodeum invagination region.
authors.affiliation: Department of Zoology, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Tagawa
authors.forename: T
authors.initials: T
authors.lastname: Humphreys
authors.forename: N
authors.initials: N
authors.lastname: Satoh
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002816:Chordata, Nonvertebrate / Q000196:embryology / Q000235:genetics*; D018076:DNA, Complementary / Q000737:chemistry / Q000235:genetics; D004268:DNA-Binding Proteins / Q000235:genetics*; D004625:Embryo, Nonmammalian / Q000737:chemistry / Q000378:metabolism*; D019143:Evolution, Molecular; D005326:Fetal Proteins; D018507:Gene Expression Regulation, Developmental; D017403:In Situ Hybridization; D008969:Molecular Sequence Data; D017422:Sequence Analysis, DNA; D020825:T-Box Domain Proteins; D014157:Transcription Factors / Q000235:genetics*; D014158:Transcription, Genetic; D000098908:Brachyury Protein
chemical_list: D018076:DNA, Complementary; D004268:DNA-Binding Proteins; D005326:Fetal Proteins; D020825:T-Box Domain Proteins; D014157:Transcription Factors; D000098908:Brachyury Protein