Identification and synthesis of novel chlorinated p-anisylpropanoid metabolites from bjerkandera species
Analysis of the EtOAc extracts from the culture medium of Bjerkandera sp. BOS55 and B. fumosa revealed the presence of two novel chlorinated metabolites. Their structures were unambiguously established as erythro-1-(3',5'-dichloro-4'-methoxyphenyl)-1, 2-propanediol (2) and 1-(3'-chloro-4'-methoxyphenyl)-3-hydroxy-1-propanone (3) through synthesis of authentic samples and comparison of retention times and mass spectral data. The production of trametol (1) by Bjerkandera sp. BOS55 was also a new finding.
Swarts
HJ
Division of Industrial Microbiology, Department of Food Technology and Nutritional Science, Wageningen Agricultural University, P.O. Box 8129, 6700 EV Wageningen, The Netherlands, and Laboratory of Organic Chemistry, Wageningen Agricultural Uni.
Verhagen
FJM
Field
JA
Wijnberg
JBPA