Glycopeptide-induced vasculitis--cross-reactivity between vancomycin and teicoplanin.
Teicoplanin has been suggested for use in patients suffering complications from vancomycin. We describe two patients who developed a vasculitic rash whilst on vancomycin with recrudescence of the rash with subsequent teicoplanin therapy.
Marshall
C
C
Pharmacy Department, Royal Melbourne Hospital, Victoria, Australia.
Street
A
A
Galbraith
K
K
D000900:Anti-Bacterial Agents / Q000009:adverse effects* / Q000627:therapeutic use; D016470:Bacteremia / Q000188:drug therapy* / Q000382:microbiology; D003429:Cross Reactions; D004342:Drug Hypersensitivity; D006801:Humans; D008297:Male; D016106:Methicillin Resistance; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000188:drug therapy*; D013211:Staphylococcus aureus; D017334:Teicoplanin / Q000009:adverse effects* / Q000627:therapeutic use; D014640:Vancomycin / Q000009:adverse effects* / Q000627:therapeutic use; D014657:Vasculitis / Q000139:chemically induced*; D014946:Wound Infection / Q000382:microbiology
D000900:Anti-Bacterial Agents; D017334:Teicoplanin; D014640:Vancomycin