title: The mouse deafness locus (dn) is associated with an inversion on chromosome 19.
abstract: Recombination data for the mouse deafness locus (dn) on chromosome 19 are consistent with the presence of an inversion for which one of the breakpoints is between D19Mit14 and D19Mit96, a distance of less than 226 kb. Fluorescence in situ hybridization studies using a bacterial artificial chromosome on interphase (G1) nuclei provide additional support for the presence of an inversion. The dn gene is probably the orthologue of the human DFNB7/DFNB11 gene on chromosome 9.
authors.affiliation: Department of Biochemistry and Molecular Biology, Louisiana State University Medical Center, New Orleans 70112, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Viñas
authors.forename: S S
authors.initials: SS
authors.lastname: Drury
authors.forename: M M
authors.initials: MM
authors.lastname: DeAngelis
authors.forename: Z
authors.initials: Z
authors.lastname: Den
authors.forename: J M
authors.initials: JM
authors.lastname: Huang
authors.forename: C I
authors.initials: CI
authors.lastname: Berlin
authors.forename: J D
authors.initials: JD
authors.lastname: Hunt
authors.forename: M A
authors.initials: MA
authors.lastname: Batzer
authors.forename: P L
authors.initials: PL
authors.lastname: Deininger
authors.forename: B J
authors.initials: BJ
authors.lastname: Keats
mesh_terms: D000818:Animals; D007446:Chromosome Inversion; D003638:Deafness / Q000235:genetics*; D016650:Fluorescein-5-isothiocyanate; D005796:Genes; D005838:Genotype; D017404:In Situ Hybridization, Fluorescence; D007178:Inbreeding; D051379:Mice; D016133:Polymerase Chain Reaction; D012235:Rhodamines
chemical_list: D012235:Rhodamines; D016650:Fluorescein-5-isothiocyanate