2C-B: a new psychoactive phenylethylamine recently discovered in Ecstasy tablets sold on the Swiss black market.
This study sought to identify, by means of several analytical methods (GC-MS, HPLC-DAD, CE-DAD, FTIR, and NMR), 4-bromo-2,5-dimethoxyphenethylamine (2C-B), which was found in two sets of tablets obtained from the Swiss black market. Unequivocal identification of 2C-B was only achieved by a combination of mass spectrometric and NMR analysis. Quantitation of 2C-B was performed by HPLC-DAD and CE-DAD. The amounts of 2C-B found in the tablets (3-8 mg) were in the range of the minimum quantity required to induce the effects characteristic of this drug.
Giroud
C
C
Laboratory of Analytical Toxicology, Institute of Legal Medicine, University of Lausanne, Switzerland.
Augsburger
M
M
Rivier
L
L
Mangin
P
P
Sadeghipour
F
F
Varesio
E
E
Veuthey
J L
JL
Kamalaprija
P
P
D002851:Chromatography, High Pressure Liquid; D004118:Dimethoxyphenylethylamine / Q000031:analogs & derivatives* / Q000032:analysis / Q000737:chemistry; D004563:Electrochemistry; D008401:Gas Chromatography-Mass Spectrometry; D006213:Hallucinogens / Q000032:analysis* / Q000737:chemistry; D013287:Illicit Drugs / Q000032:analysis* / Q000737:chemistry; D018817:N-Methyl-3,4-methylenedioxyamphetamine / Q000032:analysis* / Q000737:chemistry; D019906:Nuclear Magnetic Resonance, Biomolecular; D011619:Psychotropic Drugs / Q000032:analysis* / Q000737:chemistry; D013055:Spectrophotometry, Infrared; D013056:Spectrophotometry, Ultraviolet; D013607:Tablets
D004118:Dimethoxyphenylethylamine; D006213:Hallucinogens; D013287:Illicit Drugs; D011619:Psychotropic Drugs; D013607:Tablets; D018817:N-Methyl-3,4-methylenedioxyamphetamine; C079321:2-(4-bromo-2,5-dimethoxyphenyl)ethylamine