Composition and susceptibility to chlorhexidine of multispecies biofilms of oral bacteria.
Using a constant-depth film fermentor, we have grown a six-membered biofilm community with a bacterial composition similar to that found in supragingival dental plaque. Cryosectioning revealed the distribution of bacteria throughout the biofilm. Exposure to 0.2% chlorhexidine for up to 5 min had little effect on biofilm viability.
Pratten
J
J
Department of Microbiology, Eastman Dental Institute, University of London, London WC1X 8LD, United Kingdom. jpratten@eastman.ucl.ac.uk
Barnett
P
P
Wilson
M
M
D018441:Biofilms / Q000187:drug effects* / Q000254:growth & development; D002710:Chlorhexidine / Q000494:pharmacology*; D003773:Dental Plaque / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D008854:Microscopy, Electron; D009067:Mouthwashes / Q000494:pharmacology*
D009067:Mouthwashes; D002710:Chlorhexidine