Allergy in the airway.
BACKGROUND
Airway disease is responsible for significant morbidity worldwide and the role of allergies in the cause and persistence of airway symptoms is becoming increasingly appreciated.


OBJECTIVE
The exposure of the airway to allergens depends on the size of inhaled particles. Common allergens encountered in Australia include grass pollens, house dust mites and animal danders and sensitivity to each leads to a different clinical pattern of disease. The diagnosis of allergy requires a history of symptoms related to exposure to an allergen, together with detection of allergen-specific IgE. The evidence for the role of allergens in contributing to allergic airway disease is extensive.


CONCLUSIONS
Airway allergies are an important factor in the genesis of asthma and allergic rhinitis. There is increasing evidence that modification of exposure to allergens can improve allergic symptoms and may prevent allergic diseases. Methods of allergen avoidance are discussed.
Sutherland
M
M
Department of Allergy and Clinical Immunology, Alfred Hospital, Victoria.
Czarny
D
D
Douglass
J
J
D000485:Allergens / Q000276:immunology*; D004781:Environmental Exposure / Q000517:prevention & control; D006801:Humans; D006967:Hypersensitivity / Q000276:immunology* / Q000628:therapy; D008407:Mast Cells / Q000276:immunology; D012137:Respiratory System / Q000276:immunology*; D012140:Respiratory Tract Diseases / Q000276:immunology / Q000628:therapy; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology
D000485:Allergens