Antipruritic dinaphthofuran-7,12-dione derivatives from the pericarp of Impatiens balsamina.
Dinaphthofuran-7,12-dione derivatives named balsaminones A (1) and B (2) were isolated from the pericarp of Impatiens balsamina L. together with the known compound 2-methoxy-1,4-naphthoquinone (3). Their structures were elucidated by spectral techniques. These compounds have significant antipruritic activity.
Ishiguro
K
K
School of Pharmaceutical Sciences, Mukogawa Women's University, Koshien Kyuban-cho, Nishinomiya, 663-8179, Japan. ishiguro@mwu.mukogawa-u.ac.jp
Ohira
Y
Y
Oku
H
H
D000818:Animals; D000982:Antipruritics / Q000302:isolation & purification / Q000494:pharmacology*; D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D013058:Mass Spectrometry; D051379:Mice; D008815:Mice, Inbred Strains; D009285:Naphthoquinones / Q000302:isolation & purification / Q000494:pharmacology*; D019441:Plant Epidermis / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet
D000982:Antipruritics; D004365:Drugs, Chinese Herbal; D009285:Naphthoquinones; C115539:balsaminone A; C115540:balsaminone B; C096118:2-methoxy-1,4-naphthoquinone