[Results of the conservative surgical and irradiation treatment of 132 nonpalpable ductal carcinomas in situ of the breast].
OBJECTIVE
Retrospective analysis of results of treatment of 132 subclinical ductal carcinomas in situ, non-palpable.


METHODS
Patients were treated with limited surgery and 70 Gy radiation therapy (70 Gy).


RESULTS
With a median follow-up of 7 years, the total recurrence rate was 6%, and the actuarial rate at 5 years 4% and at 10 years 13% at. These have no influence on recurrence on the specific actuarial survival rate which was 100% at 10 years. In spite of five infiltrating recurrences of seven, no metastasis appeared 48 months after the salvage surgery. The global rate of breast preservation was 92% at 7 years.


CONCLUSIONS
Therapeutic indications were developed taking into account the present analysis and a literature review (2,338 in situ ductal carcinomas, palpable or not, treated with conservative surgery, with or without adjuvant radio-therapy).
Amalric
R
R
Académie méditerranéenne d'oncologie clinique, polyclinique Clairval, Marseille, France.
Brandone
H
H
Dubau
A
A
Hans
D
D
Brandone
J M
JM
Robert
F
F
Pollet
J F
JF
Amalric
F
F
Rouah
Y
Y
Thomassin
L
L
Giraud
D
D
Henric
A
A
Martin
P M
PM
Romain
S
S
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D002278:Carcinoma in Situ / Q000532:radiotherapy* / Q000601:surgery*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000532:radiotherapy* / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies; D016896:Treatment Outcome