title: [Pustular candidiasis in heroin addicts].
abstract: BACKGROUND
  Pustular candidiasis in heroin addicts is a rare entity in dermatology. We report a case.
  
  
  METHODS
  A 29-year-old female heroin addict developed a painful pustular growth on the scalp. There was no fever. Multiple follicular pustulae measuring 2 to 3 mm were associated with hyperesthesia of the scalp and painful cervical nodes. Biopsy showed acute ostiofolliculitis with a few blastospores and mycelial filaments. Candida albicans was isolated from the pustulae and the buccal cavity. Candida serology was positive (indirect immunofluorescence 1/100, coelectrosyneresis: 4 archs). Search for other localizations and HIV serology were negative. The last injection of brown heroin had been taken 15 days earlier; lemon had been added. Treatment with flucanazole (400 mg/d) led to improvement within 48 hours.
  
  
  CONCLUSIONS
  Sudden development of pustulae or nodules in pilous zones in a heroin addict should suggest the diagnosis. Outcome depends on early treatment after diagnosis and search for other localizations. Our case presented two particular aspects: ostiofollicular localization of the pustulae and a long delay (15 days) between the (presumably) last injection and the development of the lesion. Folliculitis develops almost exclusively in addicts who use brown heroin. Contamination by Candida albicans results from the lemon used to improve solubility at injection.
authors.affiliation: Service de Dermatologie. C.H.U. Angers.
authors.forename: C
authors.initials: C
authors.lastname: Leclech
authors.forename: B
authors.initials: B
authors.lastname: Cimon
authors.forename: J M
authors.initials: JM
authors.lastname: Chennebault
authors.forename: J L
authors.initials: JL
authors.lastname: Verret
mesh_terms: D000328:Adult; D002179:Candidiasis, Cutaneous / Q000209:etiology* / Q000473:pathology; D005260:Female; D006556:Heroin Dependence / Q000150:complications*; D006801:Humans; D012536:Scalp Dermatoses / Q000209:etiology / Q000473:pathology; D012872:Skin Diseases, Vesiculobullous / Q000209:etiology* / Q000473:pathology