title: South Portuguese population data on the loci HLA-DQA1, LDLR, GYPA, HBGG, D7S8 and Gc.
abstract: Five South Portuguese Caucasian subpopulations were analyzed for the HLA-DQA1, LDLR, GYPA, HBGG, D7S8 and Gc loci. Genotype distributions for these loci did not deviate from Hardy-Weinberg expectations. The allele and genotype frequencies found have been compared with previously published data from North and Central Portugal. A total of 11 out of 138 chi-square comparisons of allele frequencies between different Portuguese populations showed a certain degree of divergence. Alentejo, Algarve, Madeira Island and Azores Islands populations might be considered as different groups in a database. For forensic casework, a composite South Portuguese Caucasian population database was obtained for estimating multiple locus profile frequencies using the six PCR-based loci studied.
authors.affiliation: Forensic Biology Laboratory, Institute of Legal Medicine, Lisbon, Portugal.
authors.forename: R M
authors.initials: RM
authors.lastname: Brito
authors.forename: T
authors.initials: T
authors.lastname: Ribeiro
authors.forename: R
authors.initials: R
authors.lastname: Espinheira
authors.forename: H
authors.initials: H
authors.lastname: Geada
mesh_terms: D000483:Alleles; D004247:DNA / Q000032:analysis; D016172:DNA Fingerprinting / Q000379:methods; D005260:Female; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D005838:Genotype; D005936:Glucans / Q000235:genetics*; D006021:Glycophorins / Q000235:genetics*; D006683:HLA-DQ Antigens / Q000235:genetics*; D059848:HLA-DQ alpha-Chains; D006801:Humans; D008297:Male; D011110:Polymorphism, Genetic; D011174:Portugal; D011933:Reagent Kits, Diagnostic; D011973:Receptors, LDL / Q000235:genetics*; D014809:Vitamin D-Binding Protein / Q000235:genetics*
chemical_list: D005819:Genetic Markers; D005936:Glucans; D006021:Glycophorins; D006683:HLA-DQ Antigens; D059848:HLA-DQ alpha-Chains; C069050:HLA-DQA1 antigen; D011933:Reagent Kits, Diagnostic; D011973:Receptors, LDL; D014809:Vitamin D-Binding Protein; D004247:DNA; C042659:hexa(beta-glucopyranosyl)glucitol