Choreoathetoid movements associated with rapid adjustment to methadone.
Choreatiform hyperkinesias are known to be occasional movement abnormalities during intoxications with cocaine but not opiates. This is a case report of euphoria and choreoathetoid movements both transiently induced by rapid adjustment to the selective mu-opioid receptor agonist methadone in an inpatient previously abusing heroine and cocaine. In addition, minor EEG abnormalities occurred. Possible underlying neurobiological phenomena are discussed.
Bonnet
U
U
Department of General Psychiatry, University of Essen, Germany.
Banger
M
M
Wolstein
J
J
Gastpar
M
M
D000328:Adult; D001264:Athetosis / Q000139:chemically induced*; D002819:Chorea / Q000139:chemically induced*; D019970:Cocaine-Related Disorders / Q000188:drug therapy; D006556:Heroin Dependence / Q000188:drug therapy; D006801:Humans; D008297:Male; D008691:Methadone / Q000009:adverse effects* / Q000627:therapeutic use; D009294:Narcotics / Q000009:adverse effects* / Q000627:therapeutic use
D009294:Narcotics; D008691:Methadone