[Eukaryotic DNA topoisomerase and in vitro recombination between circular supercoiled plasmid DNA's in an in vitro system].
Eukaryotic DNA topoisomerase II was shown to catalyze recombination between circular supercoiled plasmid DNAs in vitro. The results obtained are discussed with regard to the organization of eukaryotic chromosomes in the form of topologically independent domains (loops).
Glazkov
M V
MV
Vavilov Institute of General Genetics, Russian Academy of Sciences, Russia.
Meshcheriakova YuA
D002384:Catalysis; D004250:DNA Topoisomerases, Type II / Q000235:genetics*; D004270:DNA, Circular / Q000235:genetics*; D004278:DNA, Superhelical / Q000235:genetics*; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics*; D010957:Plasmids / Q000235:genetics*; D011995:Recombination, Genetic
D004270:DNA, Circular; D004278:DNA, Superhelical; D004250:DNA Topoisomerases, Type II