[The factors of individual sensitivity to ultraviolet radiation].
Correlations between effective UVR doses for induction of skin erythema, premature aging and cancer, immunosuppression, vitamin D photobiosynthesis and cataract on the one hand and various ethnic signs, sex, age and metabolic states of organism on the other were considered. Individual UV sensitivity by all criteria mentioned with the exception of immunosuppression and cataract is conditioned by specificity of melanin and DNA metabolism, and risk of skin cancer incidence besides that depends of immune system state. Values of risk factors for UVR effects mentioned incidence in individuals of different sex and age with various ethnic and metabolic conditions are presented.
Strzhizhovskiĭ
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AD
State Research Centre of RF, Institute of Biomedical Problems, Moscow.
D000328:Adult; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008543:Melanins / Q000528:radiation effects; D009381:Neoplasms, Radiation-Induced / Q000209:etiology / Q000503:physiopathology; D011836:Radiation Tolerance / Q000502:physiology*; D012307:Risk Factors; D015595:Skin Aging / Q000528:radiation effects; D012878:Skin Neoplasms / Q000209:etiology / Q000503:physiopathology; D012880:Skin Pigmentation / Q000528:radiation effects; D013471:Sunburn / Q000209:etiology / Q000503:physiopathology; D014466:Ultraviolet Rays / Q000009:adverse effects*
D008543:Melanins