Giant cell tumour of bone with pulmonary metastases. A report of three cases.
Three cases of giant-cell tumour of bone with pulmonary metastases are reported. New metastases appeared and the existing nodules continued to progress after treatment in two patients who were kept under observation and no further treatment was given. When patients with giant cell tumours of bone present with lung metastases, it should be presumed that they are probably from the known tumour. However; tissue should be taken to establish the diagnosis and to exclude other concurrent lesions. Pulmonary metastases have a good long term prognosis, and so should be kept under observation, avoiding radical treatment such as lobectomy, chemotherapy and radiotherapy.
Sanjay
B K
BK
Department of Orthopaedic Surgery, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia.
Kadhi
S M
SM
D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000473:pathology*; D005260:Female; D018212:Giant Cell Tumor of Bone / Q000000981:diagnostic imaging / Q000556:secondary*; D006801:Humans; D007085:Ilium / Q000473:pathology; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D008297:Male; D008663:Metacarpus; D013977:Tibia / Q000473:pathology; D014057:Tomography, X-Ray Computed