The mouse deafness locus (dn) is associated with an inversion on chromosome 19.
Recombination data for the mouse deafness locus (dn) on chromosome 19 are consistent with the presence of an inversion for which one of the breakpoints is between D19Mit14 and D19Mit96, a distance of less than 226 kb. Fluorescence in situ hybridization studies using a bacterial artificial chromosome on interphase (G1) nuclei provide additional support for the presence of an inversion. The dn gene is probably the orthologue of the human DFNB7/DFNB11 gene on chromosome 9.
Viñas
A M
AM
Department of Biochemistry and Molecular Biology, Louisiana State University Medical Center, New Orleans 70112, USA.
Drury
S S
SS
DeAngelis
M M
MM
Den
Z
Z
Huang
J M
JM
Berlin
C I
CI
Hunt
J D
JD
Batzer
M A
MA
Deininger
P L
PL
Keats
B J
BJ
D000818:Animals; D007446:Chromosome Inversion; D003638:Deafness / Q000235:genetics*; D016650:Fluorescein-5-isothiocyanate; D005796:Genes; D005838:Genotype; D017404:In Situ Hybridization, Fluorescence; D007178:Inbreeding; D051379:Mice; D016133:Polymerase Chain Reaction; D012235:Rhodamines
D012235:Rhodamines; D016650:Fluorescein-5-isothiocyanate