[A low dose of nalbuphine reverses respiratory depression but not analgesia induced by intraspinal morphine].
Postoperative pain management after scoliosis surgery is based in our institution on intrathecal morphine administration. This case report describes an immediate and major postoperative respiratory depression that occurred in the recovery room, requiring the maintenance of the endotracheal tube. This respiratory depression was reversed by i.v. administration of a low dose of nalbuphine, which allowed tracheal extubation without suppression of morphine-induced analgesia.
Paqueron
X
X
Service d'anesthésie-réanimation, hôpital d'enfants Armand-Trousseau, Paris, France.
Galinski
M
M
Boudet
L
L
Murat
I
I
D000293:Adolescent; D000762:Anesthesia Recovery Period; D000775:Anesthesia, Spinal / Q000379:methods*; D006801:Humans; D008297:Male; D009020:Morphine / Q000008:administration & dosage* / Q000009:adverse effects / Q000037:antagonists & inhibitors; D009266:Nalbuphine / Q000494:pharmacology*; D009292:Narcotic Antagonists / Q000494:pharmacology*; D010149:Postoperative Pain / Q000628:therapy; D012131:Respiratory Insufficiency / Q000209:etiology; D012600:Scoliosis / Q000601:surgery
D009292:Narcotic Antagonists; D009020:Morphine; D009266:Nalbuphine