title: Comparable efficacy of hydrogenated versus nonhydrogenated plant sterol esters on circulating cholesterol levels in humans.
abstract: A recent study in The Netherlands compared the effects of margarine enriched with different vegetable oil sterols with margarine containing sitostanol-ester on plasma total, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) cholesterol concentrations. Margarine with sterolesters from soybean oil (mainly esters from sitosterol, campesterol, and stigmasterol) was as effective as a margarine with sitostanol-ester in lowering blood total and LDL cholesterol levels without affecting HDL cholesterol levels.
authors.affiliation: School of Dietetics and Human Nutrition, McGill University, Quebec, Canada.
authors.forename: P J
authors.initials: PJ
authors.lastname: Jones
authors.forename: F
authors.initials: F
authors.lastname: Ntanios
mesh_terms: D000328:Adult; D000368:Aged; D008076:Cholesterol, HDL / Q000097:blood / Q000187:drug effects*; D008078:Cholesterol, LDL / Q000097:blood / Q000187:drug effects*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D006865:Hydrogenation; D008297:Male; D008383:Margarine; D008875:Middle Aged; D010938:Plant Oils / Q000008:administration & dosage / Q000494:pharmacology*; D016032:Randomized Controlled Trials as Topic; D013261:Sterols / Q000008:administration & dosage / Q000494:pharmacology*
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D010938:Plant Oils; D013261:Sterols; D008383:Margarine