Bacteriology of tonsil and adenoid and sampling techniques of adenoidal bacteriology.
The value of pernasal swabs and direct adenoid swabs in chronic adenoid and adenotonsillar disease was assessed in 175 patients. Prior to adenoidectomy (53 patients) or adenotonsillectomy (122 patients), pernasal and direct adenoid swabs were taken. Adenoid currettings and tonsil tissue were cultured. Haemophilus influenzae was the bacterium most frequently isolated from adenoid currettings and from the centre (core) of the resected tonsil. There was a close relationship between the bacteriology of the pernasal swab and the adenoid tissue and tonsil core in 72 and 71% of patients, respectively. There was an identical profile of pathogens in 52 and 49%, respectively. We suggest that in children with adenoiditis or adenotonsillitis and hypertrophy of the adenoid, a pernasal swab should be used in preference to a throat swab in selecting appropriate antimicrobial therapy. Penicillin and ampicillin are not appropriate blind therapy in chronic adenoid and adenotonsillar infections because of the prevalence of beta-lactamase-producing aerobes (40%) in adenoid and tonsil core in these conditions.
Gaffney
R J
RJ
Department of Otalaryngology/Head and Neck Surgery, Beaumont Hospital, Dublin, Ireland.
Timon
C I
CI
Freeman
D F
DF
Walsh
M A
MA
Cafferkey
M T
MT
D000233:Adenoidectomy; D000234:Adenoids / Q000382:microbiology*; D000293:Adolescent; D000667:Ampicillin; D001431:Bacteriological Techniques; D002648:Child; D002675:Child, Preschool; D002908:Chronic Disease; D000075202:Contraindications; D046508:Culture Techniques; D005260:Female; D006192:Haemophilus Infections / Q000175:diagnosis; D006193:Haemophilus influenzae / Q000201:enzymology / Q000302:isolation & purification; D006801:Humans; D006984:Hypertrophy; D008297:Male; D009666:Nose / Q000382:microbiology; D014066:Palatine Tonsil / Q000382:microbiology*; D010406:Penicillins; D010614:Pharynx / Q000382:microbiology; D011008:Pneumococcal Infections / Q000175:diagnosis; D013203:Staphylococcal Infections / Q000175:diagnosis; D013211:Staphylococcus aureus / Q000302:isolation & purification; D013290:Streptococcal Infections / Q000175:diagnosis; D014068:Tonsillectomy; D014069:Tonsillitis / Q000188:drug therapy / Q000382:microbiology; D001618:beta-Lactamases / Q000378:metabolism
D010406:Penicillins; D000667:Ampicillin; D001618:beta-Lactamases