Follicular pustulous granuloma annulare.
We report a 73-year-old woman presenting with recurrent eruptions of generalized follicular pustules. Histological examination revealed several palisading necrobiotic granulomas with mucin deposits, with a perifollicular distribution. A dense neutrophilic infiltrate in the upper portion of affected follicular structures gave rise to pustulous lesions. Scaly papules and pseudovesiculous lesions over the palms with deeper necrobiotic granulomas involving sweat glands and epidermal perforation coexisted in some of the eruptions with generalized pustules. We propose the term follicular pustulous granuloma annulare for this peculiar form of granuloma annulare, which widens the clinicopathological spectrum of presentation of this disease.
Vargas-Díez
E
E
Department of Dermatology, Hospital Universitario de la Princesa, Madrid, Spain.
Feal-Cortizas
C
C
Fraga
J
J
Fernández-Herrera
J
J
García-Díez
A
A
D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D005260:Female; D016460:Granuloma Annulare / Q000188:drug therapy / Q000473:pathology*; D018859:Hair Follicle / Q000473:pathology; D006801:Humans; D011241:Prednisone / Q000627:therapeutic use
D000893:Anti-Inflammatory Agents; D011241:Prednisone