title: Adenoid cystic carcinoma of the trachea.
abstract: OBJECTIVE
  Primary tracheal tumors are rare, occurring in 0.2 per 100,000 persons per year. Adenoid cystic carcinoma (ACC) is the second most common histologic type of tracheal malignancy. Its clinical behavior is different from the other tracheal neoplasms and thus should be studied separately.
  
  
  METHODS
  Retrospective review of the medical records of six patients with tracheal ACC who were treated at University Hospitals of Cleveland between 1971 and 1996 and literature review.
  
  
  CONCLUSIONS
  Tracheal ACC is an indolent tumor that affects people at any age but has a peak incidence in the fifth decade. There is a nearly equal male-to-female ratio. Almost half of tracheal ACCs occur in the proximal trachea, accounting for the most common presenting symptoms: dyspnea, cough, and hoarseness. Because of the hoarseness, patients are often referred to an otolaryngologist. Complete resection provides the best chance for increased survival. Neutron beam radiotherapy holds promise for adjuvant therapy.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Case Western Reserve University, Cleveland, Ohio, USA. azarmoody@juno.com
authors.forename: T
authors.initials: T
authors.lastname: Azar
authors.forename: F W
authors.initials: FW
authors.lastname: Abdul-Karim
authors.forename: H M
authors.initials: HM
authors.lastname: Tucker
mesh_terms: D000328:Adult; D003528:Carcinoma, Adenoid Cystic / Q000532:radiotherapy* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014134:Tracheal Neoplasms / Q000532:radiotherapy* / Q000601:surgery*