title: Oesophageal transit time evaluated by a biomagnetic method.
abstract: The aim of this work was to determine the oesophageal transit time (OTT) of a bolus using the biomagnetic technique and compare the results to those obtained by means of scintigraphy. For the biomagnetic evaluation, a test meal (yoghurt) uniformly labelled with 5 g of powder ferrite was swallowed in a single gulp by 19 normal volunteers in the upright position. One sensor (first order gradiometer) was placed at the furcula and a second one at the xiphoid process to detect the passage of the test meal and the magnetic signal output was recorded in a computer. The OTT was determined by plotting the voltage signal against time. The scintigraphic technique was used in the same volunteers: the test meal was labelled with less than 350 MBq of 99mTc-phytate and swallowed in the same way. The bolus transit was recorded at 4 frames s(-1) (100-120 frames acquisition) and the OTT was determined by drawing two regions of interest in the same areas as the sensors. The results were determined by plotting counts against time. The averages for OTTs were 3.8 +/- 0.8 s for the scintigraphic technique and 4.6 +/- 0.9 s for the biomagnetic technique. Although scintigraphic OTT was significantly shorter than magnetic OTT, there was a significant correlation between them. We conclude that the biomagnetic study may be used to evaluate OTT.
authors.affiliation: Department of Physics and Mathematics-FFCLRP-USP, Ribeirão Preto, SP, Brazil. baffa@biomag.ffclrp.usp.br
authors.forename: N A
authors.initials: NA
authors.lastname: Daghastanli
authors.forename: F J
authors.initials: FJ
authors.lastname: Braga
authors.forename: R B
authors.initials: RB
authors.lastname: Oliveira
authors.forename: O
authors.initials: O
authors.lastname: Baffa
mesh_terms: D000328:Adult; D015374:Biosensing Techniques; D004935:Esophageal Diseases / Q000175:diagnosis*; D004947:Esophagus / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008280:Magnetics; D008297:Male; D008991:Monitoring, Physiologic / Q000295:instrumentation / Q000379:methods; D011877:Radionuclide Imaging / Q000379:methods*; D011930:Reaction Time