title: Treatment of villous hypertrophy of the choroid plexus by endoscopic contact coagulation.
abstract: Villous hypertrophy of the choroid plexus (VHCP) is a condition characterized by overproduction of cerebrospinal fluid by bilaterally symmetric and enlarged, yet histologically normal, choroid plexi. Medical and surgical therapy have been met with variable success. Traditional shunting procedures often result in failure to correct the underlying problem as well as failure to absorb the large volume of fluid produced. Craniotomy for open surgical resection of the choroid is associated with considerable morbidity. The authors describe a technique of endoscopic contact coagulation as an effective and safe treatment of VHCP. A 14-month-old hydrocephalic girl with VHCP who failed ventriculoperitoneal shunting as the sole treatment of her hydrocephalus presented with increasing ascites. She was successfully treated with ventriculoperitoneal shunting and endoscopic Bugby wire-directed monopolar contact coagulation of the hyperplastic choroid plexus. Postoperatively her head circumference and cognitive development is normal for her age, and her ascites has resolved. Endoscopic contact coagulation of the hyperplastic choroid plexus is a minimally invasive surgical method which treats the cause of the CSF production while avoiding the operative complications of open choroid plexus resection.
authors.affiliation: The Children's Hospital of Philadelphia, One Children's Center, Philadelphia, Pa., USA. philipsm@mail.med.upenn.edu
authors.forename: M F
authors.initials: MF
authors.lastname: Philips
authors.forename: G
authors.initials: G
authors.lastname: Shanno
authors.forename: A C
authors.initials: AC
authors.lastname: Duhaime
mesh_terms: D002831:Choroid Plexus / Q000473:pathology* / Q000601:surgery*; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D006849:Hydrocephalus / Q000601:surgery; D006984:Hypertrophy / Q000473:pathology / Q000601:surgery; D007223:Infant; D008279:Magnetic Resonance Imaging