Actin cytoskeleton: the Arp2/3 complex gets to the point.
Actin filament polymerization results primarily from the addition of monomers to pre-existing filaments. Recent studies have revealed that the Arp2/3 protein complex, which includes two actin-related proteins, can nucleate new actin filaments, and this capacity can be enhanced by ActA, a protein used by Listeria to polymerize actin.
Zigmond
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SH
Biology Department, University of Pennsylvania, Philadelphia 19104-6018, USA.
D051377:Actin-Related Protein 2; D051378:Actin-Related Protein 3; D000199:Actins / Q000737:chemistry / Q000502:physiology* / Q000648:ultrastructure; D000818:Animals; D001426:Bacterial Proteins / Q000737:chemistry / Q000502:physiology; D003598:Cytoskeletal Proteins; D003599:Cytoskeleton / Q000502:physiology* / Q000648:ultrastructure; D006801:Humans; D008087:Listeria / Q000502:physiology; D046911:Macromolecular Substances; D008565:Membrane Proteins / Q000737:chemistry / Q000502:physiology; D008958:Models, Molecular
C495926:ACTR2 protein, human; C495928:ACTR3 protein, human; D051377:Actin-Related Protein 2; D051378:Actin-Related Protein 3; D000199:Actins; D001426:Bacterial Proteins; D003598:Cytoskeletal Proteins; D046911:Macromolecular Substances; D008565:Membrane Proteins; C072980:actA protein, Listeria monocytogenes