title: Herpes simplex virus 1 pneumonia: patterns on CT scans and conventional chest radiographs.
abstract: OBJECTIVE
  The goal of our study was to describe the herpes simplex virus type 1 (HSV 1) pneumonia patterns on CT scans and chest radiographs.
  
  
  METHODS
  We retrospectively reviewed clinical records and chest radiographs of 24 patients with HSV 1 pneumonia and 10 with pneumonia from combined HSV and mixed flora infection. We also reviewed CT scans available for eight patients with HSV pneumonia and four with mixed pneumonia.
  
  
  RESULTS
  CT scans of eight patients with HSV pneumonia demonstrated multifocal segmental and subsegmental ground-glass opacities (n = 8), additional focal areas of consolidation (n = 6), scattered distribution (n = 6), and pleural effusions (n = 7). Chest radiographs (23 patients) showed patchy segmental and subsegmental ground-glass opacities and consolidation (n = 23), scattered distribution (n = 20), and pleural effusions (n = 12). Radiographic patterns for isolated HSV pneumonia and mixed flora pneumonia were not significantly different.
  
  
  CONCLUSIONS
  With a growing population of at-risk immunosuppressed patients, it is important to recognize CT and chest radiography patterns consistent with, although nonspecific for, HSV 1 pneumonia.
authors.affiliation: Department of Radiology, Wake Forest University School of Medicine, Winston-Salem, NC 27157-1088, USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Aquino
authors.forename: D P
authors.initials: DP
authors.lastname: Dunagan
authors.forename: C
authors.initials: C
authors.lastname: Chiles
authors.forename: E F
authors.initials: EF
authors.lastname: Haponik
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001992:Bronchoalveolar Lavage Fluid / Q000382:microbiology / Q000821:virology; D001999:Bronchoscopy; D005260:Female; D005336:Fiber Optic Technology; D006561:Herpes Simplex / Q000000981:diagnostic imaging* / Q000382:microbiology / Q000821:virology; D018259:Herpesvirus 1, Human / Q000302:isolation & purification; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging / Q000821:virology; D008297:Male; D008875:Middle Aged; D011024:Pneumonia, Viral / Q000000981:diagnostic imaging* / Q000382:microbiology / Q000821:virology; D011379:Prognosis; D013902:Radiography, Thoracic / Q000706:statistics & numerical data; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000706:statistics & numerical data