title: [Vulvar Crohn disease: 3 cases].
abstract: BACKGROUND
  Vulvar involvement in Crohn's disease is uncommon. The elementary lesion is usually an ulceration: 44 cases have been reported in the literature. In 20 p. 100 of the cases, vulvar involvement is the only manifestation of the disease. We report 3 new cases of vulvar lesions in Crohn's disease.
  
  
  METHODS
  The first case had vulvar lesions which complicated ileocolic Crohn's disease, in the other two cases there were no digestive manifestations. One patient developed voluminous edema of the right labium. The diagnosis of Crohn's disease of the vulva was suggested by the characteristic lesions, presence of epithelioid and giant cell granuloma at histology examination of the vulva specimen and finally on rapidly favorable course after treatment with sulfasalazine. The ulcers regressed with medical treatment but remission was temporary with recurrence at treatment withdrawal.
  
  
  CONCLUSIONS
  These cases underline the difficulties encountered in establishing the diagnosis of Crohn's disease in patients who develop vulvar ulcerations alone with no signs of digestive disease and emphasize the difficult problem of long-term control.
authors.affiliation: Service de Dermatologie, Hôpital La Rabta, Tunis, Tunisie.
authors.forename: S
authors.initials: S
authors.lastname: Fenniche
authors.forename: M
authors.initials: M
authors.lastname: Mokni
authors.forename: S
authors.initials: S
authors.lastname: Haouet
authors.forename: A
authors.initials: A
authors.lastname: Ben Osman
mesh_terms: D000293:Adolescent; D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003424:Crohn Disease / Q000150:complications*; D005260:Female; D006801:Humans; D019804:Mesalamine / Q000627:therapeutic use; D008875:Middle Aged; D012883:Skin Ulcer / Q000188:drug therapy / Q000209:etiology*; D012460:Sulfasalazine / Q000627:therapeutic use; D016896:Treatment Outcome; D014845:Vulvar Diseases / Q000188:drug therapy / Q000209:etiology*
chemical_list: D000893:Anti-Inflammatory Agents; D012460:Sulfasalazine; D019804:Mesalamine