A brief survey of aberration origin theories.
The salient points of three currently debated theories for chromosomal aberration origins (the Classic Breakage-and-Reunion theory, the Exchange theory, and the Molecular theory) are outlined, and some comments are made on each in the light of recent research.
Savage
J R
JR
MRC Radiation and Genome Stability Unit, Harwell, Didcot, OX11 0RD, UK.
D002842:Chromatids / Q000378:metabolism; D002869:Chromosome Aberrations / Q000235:genetics*; D019457:Chromosome Breakage / Q000235:genetics; D004260:DNA Repair; D004307:Dose-Response Relationship, Radiation; D017404:In Situ Hybridization, Fluorescence; D018499:Linear Energy Transfer; D011995:Recombination, Genetic / Q000235:genetics; D014965:X-Rays