title: Effect of distance traveled and speed of racing on body weight and serum enzyme activity of sled dogs competing in a long-distance race.
abstract: OBJECTIVE
  To determine the relationship of serum biochemical values and change in body weight with finishing status (retired from or finished the race), finishing order of a team, and distance traveled for dogs participating in a long-distance sled dog race.
  
  
  METHODS
  262 of 848 dogs that participated in the 1995 Iditarod Trail sled dog race.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  Body weight was recorded for 261 dogs before the race and again when these dogs retired from or completed the race. Using a nonrandom convenience sample of participating dogs, blood samples were obtained from 151 dogs that retired from the race and 111 dogs that completed the race.
  
  
  RESULTS
  Serum biochemical indices of skeletal muscle damage were significantly higher in dogs retiring during the first 500 miles of the race than in dogs retiring in the last 638 miles or finishing the race. Serum sodium concentration was less than the reference range in a significantly greater proportion of dogs that retired from the race than of dogs that completed the race. There was little relationship between finishing order and serum biochemical values. Dogs completing the race lost a mean of 8.9% of body weight, and amount of weight lost was not related to finishing order.
  
  
  CONCLUSIONS
  Results indicated that exertional rhabdomyolysis develops more often in dogs that retire during the initial 500 miles of a long-distance race, compared with dogs that complete the race. There is no detectable relationship between the speed with which the race is run (finishing order) and body weight loss or serum biochemical values.
authors.affiliation: Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus 43210-1089, USA.
authors.forename: K W
authors.initials: KW
authors.lastname: Hinchcliff
authors.forename: L C
authors.initials: LC
authors.lastname: Shaw
authors.forename: N S
authors.initials: NS
authors.lastname: Vukich
authors.forename: K E
authors.initials: KE
authors.lastname: Schmidt
mesh_terms: D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood*; D001774:Blood Chemical Analysis / Q000662:veterinary; D001798:Blood Proteins / Q000032:analysis; D001806:Blood Urea Nitrogen; D001835:Body Weight; D003402:Creatine Kinase / Q000097:blood*; D003430:Cross-Sectional Studies; D004285:Dogs / Q000033:anatomy & histology / Q000097:blood / Q000502:physiology*; D004573:Electrolytes / Q000097:blood; D005260:Female; D008137:Longitudinal Studies; D008297:Male; D010805:Physical Conditioning, Animal / Q000502:physiology*; D011446:Prospective Studies; D012420:Running / Q000502:physiology
chemical_list: D001798:Blood Proteins; D004573:Electrolytes; D001219:Aspartate Aminotransferases; D003402:Creatine Kinase