title: Radiation-induced optic neuropathy 4 years after radiation: report of a case followed up with MRI.
abstract: We report a case of radiation-induced optic neuropathy in a 32-year-old man with Cushing's disease and a recurrent tumour of the left cavernous sinus. The patient experienced rapid, painless loss of vision 4 years after treatment without recurrence of tumour or other visual disorder. MRI showed enlargement and contrast enhancement of the optic chiasm. A year later the patient was almost blind and MRI showed atrophy and persistent contrast enhancement of the chiasm.
authors.affiliation: Service de Medecine Interne A, Hôpital Bretonneau, CHRU de Tours, France.
authors.forename: R
authors.initials: R
authors.lastname: Piquemal
authors.forename: J P
authors.initials: JP
authors.lastname: Cottier
authors.forename: S
authors.initials: S
authors.lastname: Arsène
authors.forename: E
authors.initials: E
authors.lastname: Lioret
authors.forename: C
authors.initials: C
authors.lastname: Rospars
authors.forename: D
authors.initials: D
authors.lastname: Herbreteau
authors.forename: M
authors.initials: M
authors.lastname: Jan
authors.forename: J P
authors.initials: JP
authors.lastname: Renard
mesh_terms: D000236:Adenoma / Q000532:radiotherapy; D000328:Adult; D001766:Blindness / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009897:Optic Chiasm / Q000528:radiation effects*; D009901:Optic Nerve Diseases / Q000209:etiology* / Q000473:pathology; D010911:Pituitary Neoplasms / Q000532:radiotherapy; D011832:Radiation Injuries / Q000473:pathology*; D013997:Time Factors