title: Role of chemotherapy in the treatment of low-grade gliomas.
abstract: Being the most prevalent group of brain tumors in all age groups, low-grade gliomas still leave the question of the optimal treatment open. Despite the indolent, non-aggressive behavior of these tumors, there has been no dramatic improvement in treatment results. Surgery and radiotherapy have certain limitations in the treatment of patients with low-grade gliomas. The purpose of this review is to display a role of chemotherapy in overcoming these therapeutic obstacles. The recent reports of groups studying treatment for low-grade gliomas are analyzed.
authors.affiliation: Stephen D. Hassenfeld Children's Center for Cancer and Blood Disorders, New York University Medical Center, 317 East 34th Street, New York, NY 10016, USA
authors.initials: MM
authors.lastname: Doubrovin
authors.initials: JL
authors.lastname: Finlay