Nerve growth factor delivery systems.
Growth factors encourage tissue regeneration and differentiation, accelerate wound healing, and modulate neural repair. Thus, growth factor administration may become a useful treatment for neurodegenerative diseases, such as Alzheimer's disease or Parkinson's disease, which are characterized by the degeneration of neuronal cell populations. Controlled-release polymer delivery systems may be an important technology in enabling the prevention of neuronal degeneration, or even the stimulation of neuronal regeneration, by providing a sustained release of growth factors to promote the long-term survival of endogenous or transplanted cells.
Haller
M F
MF
School of Chemical Engineering, Cornell University, Ithaca, NY 14853, USA.
Saltzman
W M
WM
D000818:Animals; D017690:Cell Transplantation; D004337:Drug Carriers; D016503:Drug Delivery Systems; D006801:Humans; D009414:Nerve Growth Factors / Q000008:administration & dosage* / Q000627:therapeutic use; D019636:Neurodegenerative Diseases / Q000188:drug therapy; D011108:Polymers
D004337:Drug Carriers; D009414:Nerve Growth Factors; D011108:Polymers