Adenosarcoma of the uterine cervix presenting as a cervical polyp.
A case of adenosarcoma arising from the uterine cervix of a 55-year-old female who complained of vaginal discharge is reported. A polyp, 6 x 2 x 1.5 cm in size, identified in the cervical canal was clinically diagnosed as benign cervical polyp and resected. Histologically, the polyp was composed of benign epithelial components and sarcomatous stroma wherein periglandular hypercellularity and some mitoses including atypical ones were noted. Immunohistochemically, stromal cells were positive for muscle-type actins, desmin and estrogen receptor. Adenosarcoma is a rare, biphasic tumor of the uterus and usually presents as a polypoid mass in the endometrial cavity. When they arise from the cervix, adenosarcomas may be confused with benign cervical polyps clinically and pathologically. As the former often recurs, microscopic differentiation is crucial for further treatment.
Hino
A
A
Department of Pathology, University of Tokushima School of Medicine, Japan. hinoako@medbasic.basic.med.tokushima-u.ac.jp
Hirose
T
T
Seki
K
K
Uehara
H
H
Sano
N
N
D000199:Actins / Q000378:metabolism; D018256:Adenomatous Polyps / Q000473:pathology; D018195:Adenosarcoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D014408:Biomarkers, Tumor / Q000378:metabolism; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D011127:Polyps / Q000473:pathology; D011960:Receptors, Estrogen / Q000378:metabolism; D002583:Uterine Cervical Neoplasms / Q000378:metabolism / Q000473:pathology* / Q000601:surgery
D000199:Actins; D014408:Biomarkers, Tumor; D011960:Receptors, Estrogen