Contact pemphigus induced by dihydrodiphenyltrichlorethane.
We describe a case of contact pemphigus, a new subgroup of induced pemphigus. The disease is provoked by a chlorinated hydrocarbon pesticide: dihydrodiphenyltrichlorethane. We suspect that systemic absorption after the topical contact is responsible for the alteration of skin structure and activation of immunological mechanisms leading to blister formation and acantholysis.
Tsankov
N
N
Department of Dermatology, Medical University, 1, G. Sofiiskistr, Sofia, Bulgaria.
Kazandjieva
J
J
Gantcheva
M
M
D000382:Agricultural Workers' Diseases / Q000139:chemically induced*; D003634:DDT / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007306:Insecticides / Q000009:adverse effects*; D008775:Methylprednisolone / Q000008:administration & dosage; D008875:Middle Aged; D010328:Patch Tests; D010392:Pemphigus / Q000139:chemically induced* / Q000175:diagnosis
D007306:Insecticides; D003634:DDT; D008775:Methylprednisolone