title: Inhibition of demineralization in vitro around amalgam restorations.
abstract: OBJECTIVE
  The purpose of this in vitro study was to evaluate some forms of preventing or avoiding demineralization within enamel cavity walls adjacent to amalgam restorations.
  
  
  METHODS
  Third molar teeth were sectioned to obtain 72 specimens, divided into one control and five experimental groups: amalgam only; varnish plus amalgam; acidulated phosphate fluoride plus amalgam; adhesive amalgam; glass-ionomer cement plus amalgam; control (amalgam only, not subjected to a demineralization challenge). The experimental groups were subjected to PH and thermal cycling and then submitted to enamel hardness determinations.
  
  
  RESULTS
  Significant differences between the treatment groups revealed that the bonded amalgam technique offered the best resistance to demineralization. The use of cavity varnish resulted in greater mineral loss than amalgam placed alone.
  
  
  CONCLUSIONS
  The use of an adhesive system, glass-ionomer cement, or acidulated phosphate fluoride under amalgam restorations may interfere with development of secondary caries.
authors.affiliation: School of Dentistry of Piracicaba, UNICAMP, Piracicaba, São Paulo, Brazil.
authors.forename: L A
authors.initials: LA
authors.lastname: Pimenta
authors.forename: U F
authors.initials: UF
authors.lastname: Fontana
authors.forename: J A
authors.initials: JA
authors.lastname: Cury
authors.forename: M C
authors.initials: MC
authors.lastname: Serra
authors.forename: R J
authors.initials: RJ
authors.lastname: Elderton
mesh_terms: D000149:Acidulated Phosphate Fluoride; D003722:Dental Alloys; D003723:Dental Amalgam; D001840:Dental Bonding; D003731:Dental Caries / Q000209:etiology / Q000517:prevention & control; D003736:Dental Cavity Lining / Q000009:adverse effects; D003743:Dental Enamel / Q000737:chemistry; D003764:Dental Materials; D003793:Dental Restoration, Permanent / Q000009:adverse effects* / Q000379:methods; D005899:Glass Ionomer Cements; D006244:Hardness; D006801:Humans; D008963:Molar; D010710:Phosphates; D019279:Resin Cements; D012116:Resins, Plant; D017001:Tooth Demineralization / Q000209:etiology / Q000517:prevention & control*
chemical_list: D003722:Dental Alloys; D003764:Dental Materials; D005899:Glass Ionomer Cements; D010710:Phosphates; C088835:Photac-Bond; D019279:Resin Cements; D012116:Resins, Plant; C023806:Copalite; C033470:Dispersalloy; D000149:Acidulated Phosphate Fluoride; D003723:Dental Amalgam; C052304:Panavia EX