title: Erbium: YAG laser trabecular ablation (LTA) in the surgical treatment of glaucoma.
abstract: OBJECTIVE
  Laser trabecular ablation (LTA) aims to remove trabecular tissue and to open Schlemm's canal in order to improve outflow facility in glaucomatous eyes. The purpose of our study was to investigate the pressure-reducing effect of LTA in chronic open-angle glaucoma 1 year following laser surgery.
  
  
  METHODS
  Eleven eyes of 11 patients with chronic open-angle glaucoma were treated by circumscribed laser ablation of the trabecular meshwork. We used an Erbium:YAG laser (2.94 microm) with a quartz fiber contact endoprobe (320 microm core-diameter, 385 microm coating-diameter) applying 11-30 single neighbouring laser pulses (5-7 mJ) to the trabecular meshwork by an ab-interno approach. Laser procedure was gonioscopically visualized.
  
  
  RESULTS
  Mean maximum intraocular pressure (IOP) of all 11 patients before LTA was 36 mmHg and dropped down to 22 mmHg after a mean follow-up of 12 months following LTA; this represents an IOP decrease of 38% (P=0.008). The average number of medications per eye dropped from 2.8 to 1.5 per eye (P=0.021).
  
  
  CONCLUSIONS
  Although IOP lowering effect of Erbium:YAG laser trabecular ablation did not prove as effective as in filtering procedures, LTA might be a valuable alternative in glaucoma surgery especially in order to avoid conjunctival scarring and postoperative hypotony.
authors.affiliation: Department of Ophthalmology, University of Cologne, Germany.
authors.forename: T S
authors.initials: TS
authors.lastname: Dietlein
authors.forename: P C
authors.initials: PC
authors.lastname: Jacobi
authors.forename: G K
authors.initials: GK
authors.lastname: Krieglstein
mesh_terms: D000368:Aged; D005260:Female; D005902:Glaucoma, Open-Angle / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D011446:Prospective Studies; D018709:Statistics, Nonparametric; D014129:Trabecular Meshwork / Q000601:surgery; D014130:Trabeculectomy / Q000379:methods*; D016896:Treatment Outcome