The expression patterns of endothelin-A receptor and endothelin 1 in the avian embryo.
We investigated the expression pattern of the endothelin-A receptor and endothelin 1 genes, the mutations of which affect the development of the mesectodermal derivatives of the neural crest. We show here that endothelin 1 is expressed by the environment of the cephalic neural crest cells invading branchial arches. Later on, while the neural crest-derived tissues of the head continue to express endothelin-A receptor, endothelin 1 is no longer expressed in their environment.
Nataf
V
V
Institut d'Embryologie Cellulaire et Moléculaire du Centre National de la Recherche Scientifique et du Collège de France, 49 bis Avenue de la Belle Gabrielle, 94736, Nogent-sur-Marne Cedex, France.
Grapin-Botton
A
A
Champeval
D
D
Amemiya
A
A
Yanagisawa
M
M
Le Douarin
N M
NM
D000818:Animals; D002642:Chick Embryo; D004625:Embryo, Nonmammalian / Q000378:metabolism*; D019332:Endothelin-1 / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental; D017403:In Situ Hybridization; D044022:Receptor, Endothelin A; D017466:Receptors, Endothelin / Q000235:genetics*
D019332:Endothelin-1; D044022:Receptor, Endothelin A; D017466:Receptors, Endothelin