title: Acute symptomatic seizure disorders in young children--a population study in southern Taiwan.
abstract: OBJECTIVE
  To determine the incidence, etiology, and prognosis of acute symptomatic seizures in children by age 3 years.
  
  
  METHODS
  In a population-based birth cohort study of all 15,209 neonatal survivors born in Tainan City between October 1989 and December 1991, parents or caretakers of 13,493 children aged 3 years were surveyed by telephone regarding any provoked convulsive disorder, particularly acute symptomatic seizure, in the children; medical records were reviewed.
  
  
  RESULTS
  Sixty-three children (39 boys, 24 girls) had acute symptomatic seizures (incidence 0.46 in 100). The leading causes of acute symptomatic seizures were acute gastroenteritis, encephalitis/encephalopathy, and bacterial meningitis. Age-specific incidence was highest in the group aged 1-12 months. Intracranial hemorrhage, bacterial meningitis, and metabolic disturbance were the major causes of acute symptomatic seizures in children aged 1-12 months. Acute gastroenteritis, encephalitis/encephalopathy, and bacterial meningitis accounted for 85% of the causes in children aged 13-24 months, and gastroenteritis and encephalitis/encephalopathy were the predominant causes in those aged 25-36 months. By age 5 years, subsequent unprovoked seizures developed in 14% of the survivors of acute symptomatic seizures.
  
  
  CONCLUSIONS
  Many acute symptomatic seizures are preventable. The risk of subsequent unprovoked seizures is determined by underlying precipitating factors. Public education regarding the danger of shaken-baby syndrome and excessive water supplement, as well as and nationwide vaccination against bacterial meningitis in young children, is necessary.
authors.affiliation: Department of Pediatrics, National Cheng Kung University Medical Center, Tainan, Taiwan.
authors.forename: C C
authors.initials: CC
authors.lastname: Huang
authors.forename: Y C
authors.initials: YC
authors.lastname: Chang
authors.forename: S T
authors.initials: ST
authors.lastname: Wang
mesh_terms: D000208:Acute Disease; D000367:Age Factors; D001927:Brain Diseases / Q000150:complications / Q000453:epidemiology; D002543:Cerebral Hemorrhage / Q000150:complications / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004660:Encephalitis / Q000150:complications / Q000453:epidemiology; D005260:Female; D005759:Gastroenteritis / Q000150:complications / Q000453:epidemiology; D006306:Health Surveys; D006801:Humans; D015994:Incidence; D008297:Male; D016920:Meningitis, Bacterial / Q000150:complications / Q000453:epidemiology; D008659:Metabolic Diseases / Q000150:complications / Q000453:epidemiology; D012640:Seizures / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology*; D012737:Sex Factors; D013624:Taiwan / Q000453:epidemiology