title: Residual host cell protein from continuous cell lines. Effect on the safety of protein pharmaceuticals.
abstract: The presence of residual host cell proteins in protein pharmaceuticals obtained from continuous mammalian cell lines has been a point of concern. Clinical experience with different biopharmaceuticals shows that residual protein in these highly purified products does not represent a danger to the health of the patients.
authors.affiliation: Sanofi Recherche, Centre de Labège, France.
authors.forename: J H
authors.initials: JH
authors.lastname: Lupker
mesh_terms: D000818:Animals; D018929:Cell Culture Techniques / Q000592:standards*; D002460:Cell Line; D006801:Humans; D009857:Oncogenes; D011506:Proteins / Q000235:genetics; D013678:Technology, Pharmaceutical / Q000592:standards*
chemical_list: D011506:Proteins