title: Indocyanine green angiographic findings of lacquer cracks in pathologic myopia.
abstract: Lacquer cracks are thought to represent healed mechanical breaks in the retinal pigment epithelium, Bruch's membrane, and choriocapillaris complex. In this study, we analyzed the indocyanine green (ICG) angiographic features of lacquer cracks and compared them with findings using fluorescein angiography. Complete ophthalmologic examinations, fluorescein angiography, and ICG angiography were performed in 29 consecutive patients (37 eyes) with lacquer cracks. Fluorescein angiograms of the cracks revealed linear hyperfluorescence in all 37 eyes. Using ICG angiography, we observed linear hypofluorescence in all 37 eyes. In 15 of 37 eyes, the length of the hypofluorescent lesion detected by ICG angiography was longer than the hyperfluorescent lesion observed by fluorescein angiography. In 17 of 37 eyes, more lacquer cracks were observed by ICG angiography than by fluorescein angiography. These findings indicate that ICG angiography can detect the development of the lesion more precisely, and may provide useful information for diagnosing pathologic myopia.
authors.affiliation: Department of Ophthalmology, School of Medicine, Tokyo Medical and Dental University, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Ohno-Matsui
authors.forename: N
authors.initials: N
authors.lastname: Morishima
authors.forename: M
authors.initials: M
authors.lastname: Ito
authors.forename: T
authors.initials: T
authors.lastname: Tokoro
mesh_terms: D000293:Adolescent; D000328:Adult; D016570:Bruch Membrane / Q000473:pathology*; D002829:Choroid / Q000098:blood supply; D004396:Coloring Agents / Q000008:administration & dosage; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D005654:Fundus Oculi; D006801:Humans; D007208:Indocyanine Green / Q000008:administration & dosage; D007262:Infusions, Intravenous; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000150:complications*; D010857:Pigment Epithelium of Eye / Q000473:pathology; D012162:Retinal Degeneration / Q000209:etiology / Q000473:pathology; D012167:Retinal Perforations / Q000209:etiology* / Q000473:pathology; D012189:Retrospective Studies; D014741:Video Recording
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green