[Models of arterial pressure using a Windkessel type model: role of the functional arterial properties].
The Windkessel model is a linear model which does not take into account the structural and functional variations of the arteries related to the pulsatility of the blood pressure (BP) and its variations between systole and diastole.


OBJECTIVE
To analyse the performance of a BP modelisation where the parameters of AC are adjusted in a dynamic fashion according to a curvilinear relationship of the arterial properties (compliance) in relationship to the BP between systole and diastole.


METHODS
9 control subjects (age 25 +/- 3). The non invasive measures of the radial BP waveform (Millar tonometry) was compared to that constructed by an electric simulator reproducing the model in a sysmetrical network subdivised into 121 segments where we introduced for each subject: at cardiac level, the aortic stroke volume (Doppler echocardiography), and at the radial level, the dynamic values of compliance and diameter according to an arc-tangent model (measured by arterial echography NiUS02).


RESULTS
The BP obtained by the adjusted model, where the AC parameter follows the curvilinear, relationship dV/dP measured experimentally, was not significantly different from the experimental, while in the constant model (AC at mean BP level) the systolic BP was different.


CONCLUSIONS
This work shows in an experimental way the limits inherent in simplification in the Windkessel modelisation of the vascular system with constant parameters. It shows in a conduction artery the influence of the functional properties of the arterial wall on the level of systolic and diastolic BP.
Diourté
B
B
Service de médecine interne et de cardiologie, CHU, Grenoble.
Siché
J P
JP
Comparat
V
V
Baguet
J P
JP
Mallion
J M
JM
D000328:Adult; D001158:Arteries / Q000502:physiology*; D001794:Blood Pressure; D003187:Compliance; D003971:Diastole; D004452:Echocardiography; D005260:Female; D006801:Humans; D016014:Linear Models; D008297:Male; D008955:Models, Cardiovascular; D013599:Systole