title: [Pretibial epidermolysis bullosa. A rare form of epidermolysis bullosa simplex].
abstract: BACKGROUND
  Pretibial epidermolysis bullosa had been classified as a rare localized form of autosomal dominant dystrophic epidermolysis bullosa.
  
  
  METHODS
  We report a sporadic case of a patient suffering from bullous lesions induced by minor trauma on pretibial skin. The lesions healed with atrophic scars. No milia formation was observed. The mapping of dermoepidermal junction by LH 7:2 and GB3 monoclonal antibodies was normal. By electron microscopy, numerous perinuclear vacuoles were observed and the cleavage occurred within the basal keratinocytes.
  
  
  CONCLUSIONS
  This patient had clinical features in accordance with a diagnosis of pretibial epidermolysis bullosa. However, in contrast to previous case reports, the ultrastructural pattern was this of an epidermolysis bullosa of simplex type.
authors.affiliation: Polyclinique de Dermatologie, Hôpital Saint-Louis, Paris.
authors.forename: P
authors.initials: P
authors.lastname: Tsianakas
authors.forename: S
authors.initials: S
authors.lastname: Fraitag
authors.forename: A
authors.initials: A
authors.lastname: Archimbaud
authors.forename: O
authors.initials: O
authors.lastname: Verola
authors.forename: C
authors.initials: C
authors.lastname: Paul
authors.forename: C
authors.initials: C
authors.lastname: Prost
mesh_terms: D000328:Adult; D016110:Epidermolysis Bullosa Simplex / Q000209:etiology / Q000473:pathology*; D006801:Humans; D015603:Keratinocytes / Q000648:ultrastructure; D007868:Leg Dermatoses / Q000209:etiology / Q000473:pathology*; D007869:Leg Injuries / Q000150:complications; D008297:Male; D013977:Tibia