Pathophysiology of diabetes mellitus.
The most common types of diabetes observed in a primary care practice are type 1, type 2, and gestational diabetes. Type 1 diabetes is an autoimmune disease characterized by total destruction of the pancreatic beta cells, whereas insulin resistance, impaired insulin secretion, and inappropriate hepatic glucose secretion characterize type 2 diabetes. Gestational diabetes is similar to type 2 diabetes, but is first diagnosed during pregnancy.
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Veterans Affairs Puget Sound Health Care System, Seattle Division, WA 98108, USA.
D001786:Blood Glucose / Q000378:metabolism; D003922:Diabetes Mellitus, Type 1 / Q000209:etiology / Q000378:metabolism* / Q000503:physiopathology; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology / Q000378:metabolism* / Q000503:physiopathology; D016640:Diabetes, Gestational / Q000209:etiology / Q000378:metabolism* / Q000503:physiopathology; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D007328:Insulin / Q000502:physiology; D007333:Insulin Resistance; D011247:Pregnancy; D012307:Risk Factors
D001786:Blood Glucose; D007328:Insulin