Repetitive exon 45/46-related sequences of human Ca2+ channel alpha1C subunit gene.
We found in the Ca2+ channel alpha1C subunit gene a new repetitive element of three paired exon 45/46-related sequences. We also identified a new exon 45/46-related sequence in the human genome and mapped it by fluorescence in situ hybridization to the 12p11.2 and 12p13.2-p13.1 bands. These positions are not recognized by DNA probes generated from the 5'- and 3'-terminal regions of the alpha1C gene. A possible existence of a new genomic homologue of the alpha1C subunit gene is discussed.
Soldatov
N M
NM
Department of Pharmacology, Georgetown University Medical Center, Washington, D.C., USA. Soldato@medlib.georgetown.edu
Raudsepp
T
T
Chowdhary
B P
BP
D001483:Base Sequence; D015220:Calcium Channels / Q000235:genetics*; D002874:Chromosome Mapping; D002881:Chromosomes, Human, Pair 12; D018076:DNA, Complementary; D005091:Exons; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D008969:Molecular Sequence Data; D012091:Repetitive Sequences, Nucleic Acid; D012689:Sequence Homology, Nucleic Acid
D015220:Calcium Channels; D018076:DNA, Complementary