Genotyping in clinical trials: towards a principle of informed request.
This paper reviews the usefulness of bioethical instruments such as the informed consent principle to handle ethical and political challenges of clinical trials in genotyping and DNA-banking and discusses an informed request model as well as other contractual relations between research institutions, patients, and their families.
Sass
H M
HM
Ruhr Universität Bochum, Germany.
D001675:Bioethics; D018070:Biological Specimen Banks; D002986:Clinical Trials as Topic; D003219:Confidentiality; D032962:Consent Forms; D032982:Contracts; D004247:DNA; D030561:Databases, Nucleic Acid; D030661:Genetic Privacy; D036281:Genetic Research; D005838:Genotype; D006801:Humans; D007258:Informed Consent; D008499:Medical Records; D026706:Paternalism; D010344:Patient Advocacy; D026684:Personal Autonomy; D035842:Research Subjects; D035844:Researcher-Subject Relations; D018570:Risk Assessment
D004247:DNA