Cellular mechanisms of aquaporin trafficking.
Aquaporins (AQPs) are a family of functionally important water channel proteins that are of special cell biological interest because of their diverse intracellular targeting and trafficking properties. AQPs have been found in many different cells and tissues. This short review summarizes recent work that addresses the regulation of AQP2 trafficking in response to vasopressin.
Brown
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Renal Unit and Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129, USA.
Katsura
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Gustafson
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D000818:Animals; D051399:Aquaporin 2; D051403:Aquaporin 6; D020346:Aquaporins; D017868:Cyclic AMP-Dependent Protein Kinases / Q000378:metabolism; D003599:Cytoskeleton; D006706:Homeostasis; D006801:Humans; D007473:Ion Channels / Q000378:metabolism*; D007684:Kidney Tubules / Q000378:metabolism; D010766:Phosphorylation; D014667:Vasopressins / Q000494:pharmacology
C496023:AQP2 protein, human; D051399:Aquaporin 2; D051403:Aquaporin 6; D020346:Aquaporins; D007473:Ion Channels; D014667:Vasopressins; D017868:Cyclic AMP-Dependent Protein Kinases