Autoimmunity in diabetic autonomic neuropathy: does the immune system get on your nerves?
Symptomatic autonomic neuropathy is a devastating occasional complication of diabetes mellitus, especially Type 1. Although the full-blown clinical syndrome is not common, dysfunction of the autonomic nerves is detectable in up to 40% of Type 1 diabetic patients but its aetiopathogenesis is poorly understood. There is evidence to suggest that the damage to the autonomic nerves may be immune-mediated. This evidence is reviewed in the following article.
Ejskjaer
N T
NT
Department of Diabetes, King's College School of Medicine and Dentistry, London, UK.
Zanone
M M
MM
Peakman
M
M
D015551:Autoimmunity; D001342:Autonomic Nervous System Diseases / Q000276:immunology*; D003929:Diabetic Neuropathies / Q000276:immunology*; D006801:Humans; D007107:Immune System / Q000276:immunology