[Antithrombin-III in preeclampsia-eclampsia. Pilot study].
The functional levels of AT-III were determined to the following groups: A. Eleven healthy non pregnant women B. Thirteen healthy pregnant women (third trimester). C. Six preeclamptic patients. D. Five patients with eclampsia and/or HELP syndrome. The results were as follows: [table: see text] A different grade of DIC may explain the low activity of AT-III in preeclampsia and a more severe coagulation disorder in eclampsia and HELP syndrome. Our preliminary results encourage other prospective studies including larger populations to determine its usefulness as early diagnostic test and severity marker of the disease.
Verduzco Rodríguez
L
L
Hospital Regional de Río Blanco, Veracruz.
González Puebla
E
E
López Ariza
B
B
Manffrini Madrid
F
F
D000328:Adult; D000990:Antithrombin III / Q000032:analysis*; D004461:Eclampsia / Q000097:blood*; D005260:Female; D006801:Humans; D010865:Pilot Projects; D011225:Pre-Eclampsia / Q000097:blood*; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011446:Prospective Studies; D015842:Serine Proteinase Inhibitors / Q000097:blood*
D015842:Serine Proteinase Inhibitors; D000990:Antithrombin III