Parallel projection of amplitude and phase information from the hindbrain to the midbrain of the African electric fish Gymnarchus niloticus.
Two distinct sensory cues in electrosensory signals, amplitude modulation and differential phase modulation, are essential for an African wave-type electric fish, Gymnarchus, to perform the jamming avoidance responses. Individual neurons in the first brain station for central processing, the electrosensory lateral line lobe (ELL), were investigated by the in vivo whole-cell recording and labeling technique for their physiological responses, location, morphology, and projection areas. Neurons in the dorsal zone of the ELL responded selectively to amplitude modulation. Neurons in the outer cell layer of the medial zone were categorized physiologically into two groups: amplitude-sensitive and differential phase-sensitive. All but one neuron in the inner cell layer of the medial zone responded exclusively to differential phase modulation. All neurons recorded and labeled in the ELL had pyramidal morphology with large and extensive apical dendrites and less extensive basal dendrites. They were found to project to two midbrain nuclei: the nucleus praeeminentialis and the torus semicircularis. Amplitude-sensitive neurons in the dorsal zone projected exclusively to the lateral posterior subdivision, the torus semicircularis. Neurons in the medial zone projected to the medial dorsal and lateral anterior subdivisions of the torus semicircularis. Although some neurons in the ELL responded to both amplitude and differential phase modulation, they did not differentiate between temporal patterns of the two cues that encode necessary information for the jamming avoidance response. Overlapping projection of amplitude and differential phase-sensitive neurons to the torus semicircularis suggests integration of the two sensory cues in this nucleus.
Kawasaki
M
M
Department of Biology, University of Virginia, Charlottesville, Virginia 22903, USA.
Guo
Y X
YX
D000818:Animals; D001362:Avoidance Learning / Q000502:physiology; D048429:Cell Size / Q000502:physiology; D004555:Electric Fish / Q000502:physiology*; D004558:Electric Stimulation; D008636:Mesencephalon / Q000166:cytology* / Q000502:physiology*; D009434:Neural Pathways; D009474:Neurons / Q000166:cytology / Q000502:physiology; D018408:Patch-Clamp Techniques; D012249:Rhombencephalon / Q000166:cytology* / Q000502:physiology*; D013017:Sound Localization / Q000502:physiology