title: Computer-based image analysis of nucleoli in prostate carcinoma.
abstract: The authors have evaluated the nucleoli in 37 cases of prostatic carcinoma. The increase in Gleason's grade 1 correlated with an increase in the percentage of nucleolated nuclei. The increase in the percentage of bi- and trinucleolated nuclei was accompanied by a decrease of the uninucleated nuclei. The values of morphometrical parameters studied in the individual nucleoli (area, perimeter, diameters) increased in Gleason grade 2 tumors as compared with grade 1 tumors. In tumors higher grades there was, however, a progressive decrease of these values.
authors.affiliation: Department of Morphopathology, University of Medicine and Pharmacy.
authors.forename: C D
authors.initials: CD
authors.lastname: Olinici
authors.forename: D
authors.initials: D
authors.lastname: Crişan
authors.forename: C I
authors.initials: CI
authors.lastname: Olinici
authors.forename: M
authors.initials: M
authors.lastname: Vaida
mesh_terms: D002466:Cell Nucleolus / Q000473:pathology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery