title: Computational analyses and annotations of the Arabidopsis peroxidase gene family.
abstract: Classical heme-containing plant peroxidases have been ascribed a wide variety of functional roles related to development, defense, lignification, and hormonal signaling. More than 40 peroxidase genes are now known in Arabidopsis thaliana for which functional association is complicated by a general lack of peroxidase substrate specificity. Computational analysis was performed on 30 near full-length Arabidopsis peroxidase cDNAs for annotation of start codons and signal peptide cleavage sites. A compositional analysis revealed that 23 of the 30 peroxidase cDNAs have 5' untranslated regions containing 40-71% adenine, a rare feature observed also in cDNAs which predominantly encode stress-induced proteins, and which may indicate translational regulation.
authors.affiliation: Department of Protein Chemistry, Institute of Molecular Biology, University of Copenhagen, Denmark.
authors.forename: L
authors.initials: L
authors.lastname: Ostergaard
authors.forename: A G
authors.initials: AG
authors.lastname: Pedersen
authors.forename: H M
authors.initials: HM
authors.lastname: Jespersen
authors.forename: S
authors.initials: S
authors.lastname: Brunak
authors.forename: K G
authors.initials: KG
authors.lastname: Welinder
mesh_terms: D000225:Adenine / Q000032:analysis; D000595:Amino Acid Sequence; D017360:Arabidopsis / Q000201:enzymology* / Q000235:genetics; D003062:Codon; D018076:DNA, Complementary / Q000737:chemistry; D008969:Molecular Sequence Data; D009195:Peroxidase / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D011061:Poly A / Q000378:metabolism; D014176:Protein Biosynthesis; D021382:Protein Sorting Signals / Q000737:chemistry / Q000378:metabolism; D012333:RNA, Messenger / Q000737:chemistry / Q000378:metabolism; D013379:Substrate Specificity
chemical_list: D003062:Codon; D018076:DNA, Complementary; D021382:Protein Sorting Signals; D012333:RNA, Messenger; D011061:Poly A; D009195:Peroxidase; D000225:Adenine