Innovative pharmacologic approaches to cardiopulmonary resuscitation.
The survival rate of patients undergoing cardiopulmonary resuscitation (CPR) is 5% to 15%. New treatment approaches under investigation for CPR include the use of vasopressin as a vasopressor, amiodarone for the treatment of ventricular tachyarrhythmia, and adenosine antagonists (i.e., theophylline) for bradyasystolic rhythms. More innovative approaches include the use of thyroid hormone and endothelin.
Frishman
W H
WH
Department of Medicine, New York Medical College/Westchester Medical Center, Valhalla 10595, USA.
Vahdat
S
S
Bhatta
S
S
D000638:Amiodarone / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D000889:Anti-Arrhythmia Agents / Q000494:pharmacology / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000494:pharmacology / Q000627:therapeutic use; D016887:Cardiopulmonary Resuscitation / Q000379:methods*; D019332:Endothelin-1 / Q000494:pharmacology / Q000627:therapeutic use; D006323:Heart Arrest / Q000188:drug therapy* / Q000628:therapy; D006801:Humans; D014662:Vasoconstrictor Agents / Q000494:pharmacology / Q000627:therapeutic use; D014667:Vasopressins / Q000494:pharmacology / Q000627:therapeutic use
D000889:Anti-Arrhythmia Agents; D000959:Antihypertensive Agents; D019332:Endothelin-1; D014662:Vasoconstrictor Agents; D014667:Vasopressins; D000638:Amiodarone