[Treatment results in children with B-cell lymphomas using a modified BFM protocol].
OBJECTIVE
Trial of the modified protocol BFM in the treatment of children with B-cell lymphomas.


METHODS
26 children with B-cell lymphoma were treated. Of them 2 children were treated according to the program for risk 2 group and 24 children were treated as risk 3 group.


RESULTS
Complete remission was achieved in 23 patients. Two children were resistant. There were 2 cases of early recurrence, 1 case of early death, 1 case of death in remission. 20 patients are in complete remission. The 4-year survival is 78%.


CONCLUSIONS
The modified protocol BFM proved to be highly effective against B-cell lymphoma in children. Its drawback is high toxicity.
Belogurova
M B
MB
Raulesku
G G
GG
Kirichenko
M M
MM
Viktorovich
T D
TD
Goroshko
G N
GN
Chavpetsova
E D
ED
Kolygin
B A
BA
D000293:Adolescent; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D009367:Neoplasm Staging; D012074:Remission Induction; D012307:Risk Factors