title: F-18 FDG whole-body positron emission tomography scan in primary breast sarcoma.
abstract: Three patients with primary breast sarcoma showed intense F-18 FDG breast uptake on the whole-body scan. In two patients the uptake was irregular and associated with cold foci that corresponded to hypodense lesions noted on the chest CT; these represented areas of pathologically demonstrated tumor necrosis. There was also intense FDG uptake in pulmonary, axillary, and supraclavicular lymph node metastases. All lesions were confirmed by CT scan of the chest. Thus F-18 FDG positron emission tomographic scanning accurately staged the tumors in these two patients, and it documented local recurrence in the third patient. Histopathologic examination showed evidence of a high-grade sarcoma, a primary rhabdomyosarcoma, and a malignant cystosarcoma phyllodes of the breast. Similar to breast carcinoma, F-18 FDG whole-body positron emission tomographic imaging could be useful in diagnosing and staging primary breast sarcomas.
authors.affiliation: Department of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.
authors.forename: S M
authors.initials: SM
authors.lastname: Bakheet
authors.forename: J
authors.initials: J
authors.lastname: Powe
authors.forename: A
authors.initials: A
authors.lastname: Ezzat
authors.forename: H
authors.initials: H
authors.lastname: Al Suhaibani
authors.forename: A
authors.initials: A
authors.lastname: Tulbah
authors.forename: A
authors.initials: A
authors.lastname: Rostom
mesh_terms: D000293:Adolescent; D000328:Adult; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D008207:Lymphatic Metastasis; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D003557:Phyllodes Tumor / Q000000981:diagnostic imaging; D019275:Radiopharmaceuticals; D018232:Rhabdomyosarcoma, Alveolar / Q000000981:diagnostic imaging; D012509:Sarcoma / Q000000981:diagnostic imaging*; D014055:Tomography, Emission-Computed; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18