title: [Comparative analysis of changes in respiration and systemic hemodynamics during activation of GABA receptors in cats and rats].
abstract: Effects of alpha-hydroxybutyrate (GHB) involved a decrease in the respiration rate and subsequent periodic breathing in anesthetised cats and rats. No considerable changes occurred in systemic circulation. There were, however, some differences between the species in the patterns of respiratory arrest. Possible mechanisms of the similarity and difference are discussed.
authors.affiliation: Research Institute of General Pathology and Pathophysiology, Russia.
authors.forename: I A
authors.initials: IA
authors.lastname: Tarakanov
authors.forename: V A
authors.initials: VA
authors.lastname: Safonov
mesh_terms: D000818:Animals; D002415:Cats; D005260:Female; D018755:GABA Agonists / Q000494:pharmacology; D006439:Hemodynamics / Q000187:drug effects* / Q000502:physiology; D006885:Hydroxybutyrates / Q000494:pharmacology; D008297:Male; D009942:Organometallic Compounds / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D018079:Receptors, GABA / Q000187:drug effects* / Q000502:physiology; D012119:Respiration / Q000187:drug effects* / Q000502:physiology; D012131:Respiratory Insufficiency / Q000139:chemically induced / Q000503:physiopathology; D013045:Species Specificity
chemical_list: D018755:GABA Agonists; D006885:Hydroxybutyrates; D009942:Organometallic Compounds; D018079:Receptors, GABA; C022826:lithium hydroxybutyrate; C031570:2-hydroxybutyric acid