title: [Sickle cell anemia and internal cerebral vein thrombosis].
abstract: Cerebrovascular disorders are frequently associated with sickle cell disease, mainly in homozygous children. We report the case a 25-old-patient with known sickle cell disease who presented with coma inaugurated by manifestations of intracranial hypertension. CT revealed bilateral thalamic infarcts and angiography confirmed the thrombosis of internal cerebral veins. Treatment included heparin and blood transfusion. Severe cerebral oedema resulted in the lethal outcome three days later.
authors.affiliation: Département anesthésie-réanimation, hôpital neurologique et neurochirurgical Pierre-Wertheimer, Lyon, France.
authors.forename: C
authors.initials: C
authors.lastname: Di Roio
authors.forename: C
authors.initials: C
authors.lastname: Jourdan
authors.forename: A
authors.initials: A
authors.lastname: Terrier
authors.forename: F
authors.initials: F
authors.lastname: Artru
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications*; D000925:Anticoagulants / Q000627:therapeutic use; D001803:Blood Transfusion; D001929:Brain Edema / Q000209:etiology; D002550:Cerebral Veins; D003128:Coma / Q000209:etiology; D017809:Fatal Outcome; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D002542:Intracranial Embolism and Thrombosis / Q000209:etiology*; D019586:Intracranial Hypertension / Q000209:etiology; D008297:Male; D013788:Thalamus / Q000098:blood supply
chemical_list: D000925:Anticoagulants; D006493:Heparin