title: Influence of lipid composition on pediocin PA-1 binding to phospholipid vesicles.
abstract: Pediocin PA-1 bound to anionic lipid vesicles with saturated or unsaturated fatty acid chains in a lipid concentration-dependent fashion. Little change in binding parameters was observed for zwitterionic lipid vesicles. Decreasing the anionic lipid content of the vesicles gave a higher relative dissociation constant for the peptide-lipid interactions and further supports the electrostatic interaction model of binding.
authors.affiliation: Department of Food Science, Cook College, Rutgers, The State University of New Jersey, New Brunswick, New Jersey 08901, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Chen
authors.forename: R D
authors.initials: RD
authors.lastname: Ludescher
authors.forename: T J
authors.initials: TJ
authors.lastname: Montville
mesh_terms: D001430:Bacteriocins / Q000737:chemistry / Q000378:metabolism*; D001665:Binding Sites; D005227:Fatty Acids / Q000032:analysis*; D008081:Liposomes / Q000737:chemistry* / Q000378:metabolism*; D000070017:Pediocins; D010743:Phospholipids / Q000032:analysis*; D011485:Protein Binding
chemical_list: D001430:Bacteriocins; D005227:Fatty Acids; D008081:Liposomes; D000070017:Pediocins; D010743:Phospholipids; C074288:pediocin PA-1