title: A novel member of the bombyxin gene family: structure and expression of bombyxin G1 gene, an insulin-related peptide gene of the silkmoth Bombyx mori.
abstract: Bombyxin G1 gene, a novel insulin-related peptide gene of the silkmoth Bombyx mori, has been identified. The G1 gene encodes a precursor peptide which shows 41-56% and 28% sequence identities with preprobombyxins previously characterized and human preproinsulin, respectively. The G1 gene forms a pair with bombyxin C2 gene with opposite transcriptional orientation in a bombyxin gene cluster. The bombyxin G1 mRNA in Bombyx brain was shown to locate in four pairs of medial neurosecretory cells.
authors.affiliation: Department of Biology, Faculty of Science and Graduate School of Natural Science and Technology, Kanazawa University, Kanazawa 920-1192, Japan.
authors.forename: I
authors.initials: I
authors.lastname: Yoshida
authors.forename: K
authors.initials: K
authors.lastname: Moto
authors.forename: S
authors.initials: S
authors.lastname: Sakurai
authors.forename: M
authors.initials: M
authors.lastname: Iwami
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D012831:Bombyx / Q000235:genetics* / Q000254:growth & development; D001923:Brain Chemistry; D018507:Gene Expression Regulation, Developmental; D017344:Genes, Insect / Q000235:genetics*; D007814:Larva; D008969:Molecular Sequence Data; D005810:Multigene Family / Q000235:genetics; D009479:Neuropeptides / Q000235:genetics*; D012333:RNA, Messenger / Q000032:analysis; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid; D014158:Transcription, Genetic
chemical_list: D009479:Neuropeptides; D012333:RNA, Messenger; C075028:bombyxins