title: [Management of 29 children with thyroid cancer following the Chernobyl accident].
abstract: As a consequence of the Chernobyl nuclear power plant accident, a considerable increase of thyroid cancer among contaminated children has been reported in Ukraine, Belarus and Russia. A group of 29 children aged from 5 months to 10 years (mean 4.7 years) at the time of the accident, with a papillary thyroid cancer, have been examined at the Pitié-Salpêtrière hospital in Paris. The cancer was discovered by systematic ultrasonography in only 25% of cases. No reliable dosimetric estimation was achieved. The initial surgical treatment was performed in Ukraine. Cervical lymph node and pulmonary metastases were present in 24 and 11 cases respectively. A complementary surgical treatment was necessary for 9 children and one to four radioiodine treatments were given to 24 children. With a mean delay of 7 years after the cancer discovery, an apparent cure or a remission was obtained for 20 children, 6 children have cervical lymph node metastases requiring a surgical treatment and 3 have evolving lung metastases. The management of the great number of foreseeable cases of thyroid cancer requires an improved systematic screening, a large number of rooms dedicated to high activity radioiodine treatments, funds for disposable material and training missions.
authors.affiliation: Service Biophysique 2--Groupe hospitalier Pitié-Salpétrière, Paris.
authors.forename: A
authors.initials: A
authors.lastname: Aurengo
authors.forename: T
authors.initials: T
authors.lastname: Delbot
authors.forename: L
authors.initials: L
authors.lastname: Leenhardt
authors.forename: B
authors.initials: B
authors.lastname: Franc
authors.forename: O
authors.initials: O
authors.lastname: Epstein
authors.forename: M L
authors.initials: ML
authors.lastname: Simonet
authors.forename: A
authors.initials: A
authors.lastname: Moutet
mesh_terms: D002648:Child; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D009381:Neoplasms, Radiation-Induced / Q000453:epidemiology / Q000628:therapy*; D011210:Power Plants; D018788:Radioactive Hazard Release; D013964:Thyroid Neoplasms / Q000453:epidemiology / Q000628:therapy*; D014455:Ukraine / Q000453:epidemiology