Primary antiphospholipid syndrome with recurrent transient ischemic attacks: report of a case and its successful treatment.
A 35-year-old woman was admitted to our hospital with complaints of a two-year history of recurrent, daily episodes of transient ischemic attacks; the symptoms consisted of scotoma of her left eye, vertical diplopia, and paresthesia of her right arm. The presence of lupus anticoagulants and anticardiolipin antibodies led to the diagnosis of antiphospholipid syndrome (APS). After thrombotest values had decreased to 30% (international normalized ratio: 1.5) with warfarin, her symptoms did not recur. This suggests that anticoagulant therapy is effective for the prevention of recurrence of ischemic events complicated by primary APS, even when they occur repeatedly.
Ihara
M
M
Department of Neurology, Nishi-Kobe Medical Center, Kobe, Hyogo.
Tanaka
H
H
Nishimura
Y
Y
D000328:Adult; D017153:Antibodies, Anticardiolipin / Q000097:blood; D000925:Anticoagulants / Q000627:therapeutic use*; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D005260:Female; D006801:Humans; D002546:Ischemic Attack, Transient / Q000209:etiology*; D016682:Lupus Coagulation Inhibitor / Q000097:blood; D012008:Recurrence; D014859:Warfarin / Q000627:therapeutic use*
D017153:Antibodies, Anticardiolipin; D000925:Anticoagulants; D016682:Lupus Coagulation Inhibitor; D014859:Warfarin