title: Exertional compartment syndrome of the upper extremity.
abstract: Exertional compartment syndrome is characterized by intracompartmental pressures that rise transiently following repetitive motion or exercise, thereby producing temporary, reversible ischemia, pain, weakness, and, occasionally, neurologic deficits. The exact cause or pathogenesis remains unclear; a disturbance of microvascular flow caused by elevated intramuscular pressure leads to tissue ischemia, depletion of high-energy phosphate stores, and cellular acidosis. Anatomic contributing factors may include a limited compartment size, increased intracompartmental volume, constricted fascia, loss of compartment elasticity, poor venous return, or increased muscle bulk. The diagnosis is suspected based on history and confirmed with physical examination and intramuscular pressure evaluation before and after exercise (stress test). Differential diagnosis includes claudication or other vascular abnormalities, myositis, tendinitis, periostitis, chronic strains or sprains, stress fracture, other compression or systemic neuropathies, and cardiac abnormalities with angina or referred extremity pain. Initial treatment includes activity modification; refractory symptoms can be managed with elective fasciotomy.
authors.affiliation: Hand Surgery Section, La Jolla, California, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Botte
authors.forename: J
authors.initials: J
authors.lastname: Fronek
authors.forename: R A
authors.initials: RA
authors.lastname: Pedowitz
authors.forename: H R
authors.initials: HR
authors.lastname: Hoenecke
authors.forename: R A
authors.initials: RA
authors.lastname: Abrams
authors.forename: M L
authors.initials: ML
authors.lastname: Hamer
mesh_terms: D002908:Chronic Disease; D003161:Compartment Syndromes / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000601:surgery; D012090:Cumulative Trauma Disorders / Q000150:complications; D015444:Exercise; D000071938:Fasciotomy; D006801:Humans; D012008:Recurrence