title: Pathobiology and clinical significance of molecular genetic findings in childhood tumors.
abstract: Molecular genetic determinants of malignant diseases in children are providing insights into the mechanisms of malignancies. These findings have improved diagnosis, treatment, and prognosis.
authors.affiliation: Department of Pediatrics, University of Tennessee, College of Medicine, Memphis, USA.
authors.forename: J E
authors.initials: JE
authors.lastname: Rubnitz
authors.forename: J R
authors.initials: JR
authors.lastname: Downing
authors.forename: W M
authors.initials: WM
authors.lastname: Crist
mesh_terms: D002648:Child; D016147:Genes, Tumor Suppressor / Q000235:genetics; D006801:Humans; D007951:Leukemia, Myeloid / Q000175:diagnosis / Q000235:genetics; D008223:Lymphoma / Q000175:diagnosis / Q000235:genetics; D009369:Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000473:pathology; D009447:Neuroblastoma / Q000175:diagnosis / Q000235:genetics; D009857:Oncogenes / Q000235:genetics; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis / Q000235:genetics