title: [Infantile acne and isotretinoin].
abstract: We report a case of severe infantile cystic acne, which required a treatment with oral isotretinoin.
  
  
  METHODS
  The patient, a 22-month-old boy, presented cystic acne since 6 months of age. The child was otherwise healthy and endocrine evaluation was normal. Previous treatments had no effect, oral isotretinoine led to cure without secondary effects.
  
  
  CONCLUSIONS
  The etiology of infantile acne is not clearly defined, but may result from a persisting androgen-driven stimulation of sebaceous glands. Oral isotretinoin is safe and effective in case of recalcitrant infantile acne, but close monitoring is necessary because of the well-known side effects of oral retinoids.
authors.affiliation: Unité de Dermatologie Pédiatrique, Hôpital Pellegrin-Enfants, Bordeaux.
authors.forename: C
authors.initials: C
authors.lastname: Léauté-Labrèze
authors.forename: C
authors.initials: C
authors.lastname: Gautier
authors.forename: L
authors.initials: L
authors.lastname: Labbé
authors.forename: A
authors.initials: A
authors.lastname: Taieb
mesh_terms: D000152:Acne Vulgaris / Q000188:drug therapy* / Q000209:etiology / Q000473:pathology; D000284:Administration, Oral; D000728:Androgens / Q000009:adverse effects; D016903:Drug Monitoring; D006801:Humans; D007223:Infant; D015474:Isotretinoin / Q000627:therapeutic use*; D007641:Keratolytic Agents / Q000627:therapeutic use*; D008297:Male
chemical_list: D000728:Androgens; D007641:Keratolytic Agents; D015474:Isotretinoin