title: Excision and low-dose radiotherapy for refractory laryngeal granuloma.
abstract: Laryngeal granulomas are uncommon lesions of an inflammatory origin. They are conventionally managed by simple excision with the occasional use of adjuvant treatment depending on the aetiological factors. Unfortunately, recurrences can occur, requiring repeated excision. Some lesions are refractory to this approach and alternative management approaches include excision and immediate adjuvant radiotherapy. The use of radiotherapy in the management of benign disease can be limited by the risk of induction of late malignancy and informed consent of a patient must include an assessment of this risk. We describe a case of refractory laryngeal granuloma successfully treated by excision and immediate radiotherapy in a patient occupationally dependent upon his voice.
authors.affiliation: Head and Neck Unit, Royal Marsden Hospital NHS Trust, London, UK.
authors.forename: G
authors.initials: G
authors.lastname: Mitchell
authors.forename: C R
authors.initials: CR
authors.lastname: Pearson
authors.forename: J M
authors.initials: JM
authors.lastname: Henk
authors.forename: P
authors.initials: P
authors.lastname: Rhys-Evans
mesh_terms: D003131:Combined Modality Therapy; D006102:Granuloma, Laryngeal / Q000532:radiotherapy* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009784:Occupational Diseases / Q000532:radiotherapy* / Q000601:surgery*; D011879:Radiotherapy Dosage; D012008:Recurrence