title: [Comparison of primary angioplasty and prehospital thrombolysis in the acute phase of myocardial infarction. CAPTIM Study Group].
abstract: The "Comparison of Primary Angioplasty and Prehospital Thrombolysis in the Acute Phase of Myocardial Infarction" (CAPTIM) trial compares the two best strategies of revascularisation in the acute phase of myocardial infarction. CAPTIM is a prospective, randomised, multicenter, open trial. The patients treated by the emergency ambulance service and presenting the criteria of inclusion were randomised and treated either by rtPA instituted at the pick-up point or taken to hospital for primary angioplasty. The main criterion was composite associating death, recurrent myocardial infarction and cerebrovascular accidents identified at 1 month. These events were validated by a committee independent of the study. The number of required patients was assessed to be 1,200 patients to be recruited in 2 years. CAPTIM started in June 1997 and will finish in June 1999. This study, associating the emergency ambulance service and the coronary care unit of 11 different French cities, should help define the priorities in the actions to be undertaken to optimise the treatment of acute myocardial infarction.
authors.affiliation: Hôpital Louis-Pradel, Bron.
authors.forename: P
authors.initials: P
authors.lastname: Touboul
authors.forename: E
authors.initials: E
authors.lastname: Bonnefoy
mesh_terms: D015906:Angioplasty, Balloon, Coronary; D004632:Emergency Medical Services; D005602:France; D006801:Humans; D009203:Myocardial Infarction / Q000628:therapy*; D011446:Prospective Studies; D015912:Thrombolytic Therapy