Technology and biopharmaceutical availability of solid ocular inserts containing sulfadicramide and some promoters.
Technology for obtaining solid ocular inserts made of poly(vinyl alcohol), containing sulfadicramide and some sorption promoters, was worked out. The rate of drug release was studied by assuming the pseudo-first order kinetics to hold true. An isolated animal cornea was used to measure the coefficients of permeability and the efficiency of sulfadicramide penetration through these corneas.
Grześkowiak
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Department of Physical Chemistry, K. Marcinkowski University of Medical Sciences, Poznań, Poland.
D000577:Amides / Q000493:pharmacokinetics*; D000818:Animals; D001682:Biological Availability; D004304:Dosage Forms; D005123:Eye / Q000378:metabolism*; D066298:In Vitro Techniques; D013552:Swine
D000577:Amides; D004304:Dosage Forms