title: Asbestos-related pericardial thickening detected by magnetic resonance imaging.
abstract: Magnetic resonance imaging was performed in four male asbestos workers in whom the chest radiograph revealed pleural but not pulmonary or pericardial disease. Patients underwent thoracic multislice spin echo imaging, with measurement of left and right ventricular volumes at end-diastole and end-systole, and a study of the flow in the superior vena cava as an indirect measure to the filling of the right ventricle. Patients also underwent respiratory function tests and high-resolution computed tomography (HRCT). Magnetic resonance, but not HRCT, showed pericardial thickening in two patients. Magnetic resonance demonstrated reduced diastolic flow in the superior vena cava in one patient, reflecting impaired right ventricular filling. All other magnetic resonance measurements of cardiac function were normal. HRCT demonstrated mild asbestosis in three patients in which neither the chest radiograph nor magnetic resonance showed signs of parenchymal disease, and pericardiac calcification without thickening in one patient. It is concluded that magnetic resonance is superior to HRCT in identifying pericardial thickening, but that HRCT is superior to magnetic resonance in identifying asbestos-related pleural and pulmonary disease.
authors.affiliation: London Chest Hospital, U.K.
authors.forename: N A
authors.initials: NA
authors.lastname: Jarad
authors.forename: S R
authors.initials: SR
authors.lastname: Underwood
authors.forename: R M
authors.initials: RM
authors.lastname: Rudd
mesh_terms: D000328:Adult; D001194:Asbestos / Q000009:adverse effects*; D001195:Asbestosis / Q000175:diagnosis / Q000000981:diagnostic imaging; D002302:Cardiac Output / Q000502:physiology; D002306:Cardiac Volume / Q000502:physiology; D005541:Forced Expiratory Volume / Q000502:physiology; D006331:Heart Diseases / Q000175:diagnosis; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010496:Pericardium / Q000473:pathology*; D010995:Pleural Diseases / Q000000981:diagnostic imaging; D012039:Regional Blood Flow / Q000502:physiology; D012115:Residual Volume / Q000502:physiology; D014057:Tomography, X-Ray Computed; D014109:Total Lung Capacity / Q000502:physiology; D014683:Vena Cava, Superior / Q000502:physiology; D016278:Ventricular Function, Right / Q000502:physiology; D014797:Vital Capacity / Q000502:physiology
chemical_list: D001194:Asbestos