title: [Acute mast cell leukemia disclosed by vasomotor flushing].
abstract: BACKGROUND
  Acute mast cell leukemia is a rare and severe disease. We report herein a case associated with a flush syndrome.
  
  
  METHODS
  A 44-year-old man, presented with a flush of face and trunk. Bone marrow was infiltrated with immature mast cells. In spite of chemotherapy and bone marrow transplantation the patient deceased.
  
  
  CONCLUSIONS
  Pheochromocytoma, carcinoid tumor, and mastocytosis are associated with a flush syndrome. In our patient the diagnosis was an acute mast cell leukemia. Acute mast cell leukemia can follow systemic mastocytosis or occur de novo. This disease is of poor prognosis. No treatment is available.
authors.affiliation: Service de Dermatologie, Hôpital Henri-Mondor, Créteil.
authors.forename: M T
authors.initials: MT
authors.lastname: Le Cam
authors.forename: P
authors.initials: P
authors.lastname: Wolkenstein
authors.forename: A
authors.initials: A
authors.lastname: Cosnes
authors.forename: H
authors.initials: H
authors.lastname: Bocquet
authors.forename: P
authors.initials: P
authors.lastname: Gaulard
authors.forename: M
authors.initials: M
authors.lastname: Tulliez
authors.forename: C
authors.initials: C
authors.lastname: Cordonnier
authors.forename: J C
authors.initials: JC
authors.lastname: Roujeau
authors.forename: M
authors.initials: M
authors.lastname: Bagot
authors.forename: J
authors.initials: J
authors.lastname: Revuz
mesh_terms: D000328:Adult; D001856:Bone Marrow Examination; D004890:Erythema / Q000209:etiology; D005148:Facial Dermatoses / Q000209:etiology; D017809:Fatal Outcome; D005483:Flushing / Q000209:etiology*; D006801:Humans; D007946:Leukemia, Mast-Cell / Q000150:complications* / Q000175:diagnosis; D008297:Male; D013909:Thorax