Hemodynamic effects of arbutamine.
This study examined the hemodynamic effects of arbutamine, a synthetic catecholamine, in 12 patients with and 7 patients without coronary artery disease. Arbutamine produced a balanced positive inotropic (increase in left ventricular dp/dt) and chronotropic effect (increase in heart rate).
Ogilby
J D
JD
Department of Medicine, MCP, Hahnemann School of Medicine, Allegheny University of the Health Sciences, Philadelphia, Pennsylvania 19102, USA.
Molk
B
B
Iskandrian
A E
AE
D000328:Adult; D000787:Angina Pectoris / Q000175:diagnosis*; D006328:Cardiac Catheterization; D002316:Cardiotonic Agents / Q000008:administration & dosage; D002395:Catecholamines / Q000008:administration & dosage; D003327:Coronary Disease / Q000175:diagnosis*; D004305:Dose-Response Relationship, Drug; D004562:Electrocardiography / Q000187:drug effects; D005260:Female; D006339:Heart Rate / Q000187:drug effects; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D007260:Infusion Pumps; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000187:drug effects; D012680:Sensitivity and Specificity; D015899:Tomography, Emission-Computed, Single-Photon
D002316:Cardiotonic Agents; D002395:Catecholamines; C076559:arbutamine