title: Radical trachelectomy: a way to preserve fertility in the treatment of early cervical cancer.
abstract: In the Centenary year of Wertheim's hysterectomy for the treatment of invasive cervical cancer, it is appropriate to look at less radical methods of managing early stage disease. Radical trachelectomy with pelvic lymphadenectomy is a conservative but locally radical procedure, preserving the corpus uteri and therefore fertility potential. The first 10 cases in a pilot study are presented. One patient has required post-operative radiotherapy and another a completion radical hysterectomy. Three live births by caesarean section and three other pregnancies have resulted. Careful selection within strict criteria may allow this more conservative approach without compromising cure. These procedures should be carried out in referral centres with continuing follow up and review.
authors.affiliation: Department of Gynaecological Oncology, St Bartholomew's Hospital, London, UK.
authors.forename: J H
authors.initials: JH
authors.lastname: Shepherd
authors.forename: R A
authors.initials: RA
authors.lastname: Crawford
authors.forename: D H
authors.initials: DH
authors.lastname: Oram
mesh_terms: D000328:Adult; D002584:Cervix Uteri / Q000601:surgery*; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000379:methods*; D006801:Humans; D007247:Infertility, Female / Q000517:prevention & control*; D014594:Uterine Neoplasms / Q000473:pathology / Q000601:surgery*