Role of chemotherapy in the treatment of low-grade gliomas.
Being the most prevalent group of brain tumors in all age groups, low-grade gliomas still leave the question of the optimal treatment open. Despite the indolent, non-aggressive behavior of these tumors, there has been no dramatic improvement in treatment results. Surgery and radiotherapy have certain limitations in the treatment of patients with low-grade gliomas. The purpose of this review is to display a role of chemotherapy in overcoming these therapeutic obstacles. The recent reports of groups studying treatment for low-grade gliomas are analyzed.
Doubrovin
MM
Stephen D. Hassenfeld Children's Center for Cancer and Blood Disorders, New York University Medical Center, 317 East 34th Street, New York, NY 10016, USA
Finlay
JL