title: Neuroreceptor imaging: new developments in PET and SPECT imaging of neuroreceptor binding (including dopamine transporters, vesicle transporters and post synaptic receptor sites).
abstract: Positron emission tomography and single photon emission computed tomography have been used to measure receptor concentration and function through the use of a variety of radiotracers and data analysis techniques. Changes in presynaptic function and postsynaptic receptor concentration reflect both loss due to disease and compensatory responses.
authors.affiliation: Neurodegenerative Disorders Centre, University of British Columbia, Vancouver, Canada.
authors.forename: A J
authors.initials: AJ
authors.lastname: Stoessl
authors.forename: T J
authors.initials: TJ
authors.lastname: Ruth
mesh_terms: D001692:Biological Transport / Q000502:physiology; D002352:Carrier Proteins / Q000378:metabolism; D004298:Dopamine / Q000378:metabolism; D050483:Dopamine Plasma Membrane Transport Proteins; D006801:Humans; D008562:Membrane Glycoproteins / Q000378:metabolism; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins / Q000378:metabolism; D009479:Neuropeptides; D011954:Receptors, Dopamine / Q000378:metabolism; D011984:Sensory Receptor Cells / Q000378:metabolism*; D014055:Tomography, Emission-Computed; D015899:Tomography, Emission-Computed, Single-Photon; D050492:Vesicular Biogenic Amine Transport Proteins
chemical_list: D002352:Carrier Proteins; D050483:Dopamine Plasma Membrane Transport Proteins; D008562:Membrane Glycoproteins; D026901:Membrane Transport Proteins; D009419:Nerve Tissue Proteins; D009479:Neuropeptides; D011954:Receptors, Dopamine; D050492:Vesicular Biogenic Amine Transport Proteins; D004298:Dopamine