Preventing breast cancer with tamoxifen.
Tamoxifen offers protection against the development or recurrence of breast cancer in a range of clinical circumstances, while simultaneously helping to prevent osteoporosis and perhaps coronary heart disease. The most serious side effects of this antiestrogen are thromboembolism and accelerated development of endometrial carcinoma; they occur primarily in postmenopausal women.
Jordan
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Northwestern University Medical School, Chicago, USA.
D000328:Adult; D000368:Aged; D000465:Algorithms; D016588:Anticarcinogenic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D001943:Breast Neoplasms / Q000517:prevention & control*; D017024:Chemotherapy, Adjuvant; D004965:Estrogen Antagonists / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008875:Middle Aged; D012307:Risk Factors; D013629:Tamoxifen / Q000494:pharmacology / Q000627:therapeutic use*
D016588:Anticarcinogenic Agents; D004965:Estrogen Antagonists; D013629:Tamoxifen