Xenopus eomesodermin is expressed in neural differentiation.
Our initial description of the Xenopus gene Eomesodermin (Eomes) indicated that it is expressed largely if not entirely in mesodermal cells of gastrula stage embryos. A more detailed examination, described here, shows that it continues to be expressed in the most anterior (future head) mesoderm during gastrula and neurula stages. However, during tail-bud stages, Eomes expression is re-born in the most anterior part of the brain, becoming strongly transcribed in the olfactory region of the telencephalon. This later Eomes expression marks a very localized region of the forebrain distinct from that of Otx-2, anterior to that of En-1 and overlapping that of Sox-3.
Ryan
K
K
Wellcome/CRC Institute, Tennis Court Road, Cambridge, CB2 1QR, UK.
Butler
K
K
Bellefroid
E
E
Gurdon
J B
JB
D000818:Animals; D002454:Cell Differentiation; D004268:DNA-Binding Proteins; D004625:Embryo, Nonmammalian / Q000378:metabolism; D047108:Embryonic Development; D018507:Gene Expression Regulation, Developmental; D006609:High Mobility Group Proteins; D018398:Homeodomain Proteins; D017403:In Situ Hybridization; D009419:Nerve Tissue Proteins / Q000235:genetics; D009420:Nervous System / Q000166:cytology / Q000196:embryology* / Q000378:metabolism; D051857:Otx Transcription Factors; D055748:SOXB1 Transcription Factors; D020825:T-Box Domain Proteins; D015534:Trans-Activators / Q000235:genetics; D014157:Transcription Factors / Q000235:genetics*; D014981:Xenopus / Q000196:embryology / Q000235:genetics*; D029867:Xenopus Proteins
D004268:DNA-Binding Proteins; C103223:EOMES protein, Xenopus; C081542:En1 protein, Xenopus; D006609:High Mobility Group Proteins; D018398:Homeodomain Proteins; D009419:Nerve Tissue Proteins; D051857:Otx Transcription Factors; D055748:SOXB1 Transcription Factors; C527788:Sox3 protein, Xenopus; D020825:T-Box Domain Proteins; D015534:Trans-Activators; D014157:Transcription Factors; D029867:Xenopus Proteins