title: Pulmonary sequestration: a review of 26 cases.
abstract: OBJECTIVE
  Pulmonary sequestration is a continuum of lung anomalies for which no single embryonic hypothesis is yet available. The aim of this study was to assess the diagnostic tools and treatment for the rare condition, pulmonary sequestration, in an unspecialised centre.
  
  
  METHODS
  We performed an analysis of 26 cases of pulmonary sequestration (paediatric and adult) operated at the Centre Hospitalier Universitaire Vaudois between May 1959 and May 1997. A review of the extralobar and intralobar types of sequestrations is discussed. Angiography is compared to other diagnostic tools in this condition, and treatment is discussed.
  
  
  RESULTS
  Twenty-six cases of pulmonary sequestrations, a rare congenital pulmonary malformation, were operated on in the defined time period. Seventy-three percent (19) of the cases were intralobar and 27% (seven) extralobar. Extralobar localisation was basal in 71% and situated between the upper and the lower lobe in 29%. In six cases, the diagnosis was made by exploratory thoracotomy. In the other 20 cases, diagnosis was evoked on chest X-ray and confirmed by angiography. Lobectomy (46%) was the most common treatment procedure. Segmental resection was performed in 30% of the cases and bilobectomy in 4%. Post-operative morbidity was low. The most significant complications were pleural empyema, haemothorax and haemopneumoperitoneum in case of extralobar sequestration. There was no evidence of metaplasia or pre-neoplastic changes.
  
  
  CONCLUSIONS
  Despite its rarity, some radiological features are sufficiently suggestive of diagnosis of pulmonary sequestration. Investigations are necessary in order to avoid unexpected pathology at the time of operation. Resection of the involved lung leads to excellent results and the long-term outcome is highly favourable.
authors.affiliation: Department of Surgery, CHUV, Lausanne, Switzerland.
authors.forename: N
authors.initials: N
authors.lastname: Halkic
authors.forename: P F
authors.initials: PF
authors.lastname: Cuénoud
authors.forename: M E
authors.initials: ME
authors.lastname: Corthésy
authors.forename: R
authors.initials: R
authors.lastname: Ksontini
authors.forename: M
authors.initials: M
authors.lastname: Boumghar
mesh_terms: D000328:Adult; D000792:Angiography; D001998:Bronchopulmonary Sequestration / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant; D008168:Lung / Q000473:pathology; D008297:Male; D011013:Pneumonectomy; D011183:Postoperative Complications / Q000453:epidemiology; D016896:Treatment Outcome