title: Biological and clinical study kinetics of biodegrading apatite-collagen implant for substituting bone tissue defects.
abstract: We studied kinetics of biotransformation synthetic implant for substituting defects of the bone tissue using methods of computer tomography, scintigraphy and morphology in vivo and in vitro. We found that the character of biotransformation is dependent on the degree of loaded or unloaded bone tissue.
authors.affiliation: Department of Pharmacy, Samara State Medical University, Russia.
authors.forename: S D
authors.initials: SD
authors.lastname: Litvinov
mesh_terms: D020341:Absorbable Implants; D000818:Animals; D001031:Apatites / Q000378:metabolism*; D001673:Biodegradation, Environmental; D001711:Biotransformation; D015519:Bone Density; D018786:Bone Substitutes / Q000378:metabolism*; D001133:Bones of Upper Extremity / Q000000981:diagnostic imaging / Q000601:surgery; D003094:Collagen / Q000378:metabolism*; D004285:Dogs; D006801:Humans; D007700:Kinetics; D011859:Radiography
chemical_list: D001031:Apatites; D018786:Bone Substitutes; D003094:Collagen