title: Structure of the P-type ATPases.
abstract: Electron cryocrystallography of precipitant-induced two-dimensional surface crystals of the neurospora plasma membrane H+ - ATPase and tubular crystals of the sarcoplasmic reticulum Ca(2+)-ATPase has recently yielded structure maps for these ion transporters at a resolution of about 8 A. The membrane-embedded regions of these closely related enzymes are similar, but the cytoplasmic regions appear to be significantly different.
authors.affiliation: Max-Planck-Institut für Biophysik, Abteilung Strukturbiologie, Frankfurt am Main, Germany. kuehlbrandt@biophys.mpg.de
authors.forename: W
authors.initials: W
authors.lastname: Kühlbrandt
authors.forename: M
authors.initials: M
authors.lastname: Auer
authors.forename: G A
authors.initials: GA
authors.lastname: Scarborough
mesh_terms: D000252:Calcium-Transporting ATPases / Q000737:chemistry* / Q000378:metabolism; D008958:Models, Molecular; D011487:Protein Conformation; D006180:Proton-Translocating ATPases / Q000737:chemistry* / Q000378:metabolism
chemical_list: D006180:Proton-Translocating ATPases; D000252:Calcium-Transporting ATPases