Cerebral blood flow measurements by magnetic resonance imaging bolus tracking: comparison with [(15)O]H2O positron emission tomography in humans.
In six young, healthy volunteers, a novel method to determine cerebral blood flow (CBF) using magnetic resonance (MR) bolus tracking was compared with [(15)O]H2O positron emission tomography (PET). The method yielded parametric CBF images with tissue contrast in good agreement with parametric PET CBF images. Introducing a common conversion factor, MR CBF values could be converted into absolute flow rates, allowing comparison of CBF values among normal subjects.
Ostergaard
L
L
Department of Neuroradiology, Arhus University Hospital, Denmark.
Johannsen
P
P
Høst-Poulsen
P
P
Vestergaard-Poulsen
P
P
Asboe
H
H
Gee
A D
AD
Hansen
S B
SB
Cold
G E
GE
Gjedde
A
A
Gyldensted
C
C
D000328:Adult; D002560:Cerebrovascular Circulation / Q000502:physiology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D010104:Oxygen Radioisotopes; D012016:Reference Values; D014055:Tomography, Emission-Computed / Q000379:methods*; D014867:Water / Q000378:metabolism
D010104:Oxygen Radioisotopes; D014867:Water