Chronic renal failure: an overview from a pediatric perspective.
We present data on the costs and impact of chronic renal failure, the primary renal diseases leading to end-stage renal disease in children, and review the adaptive responses and the pathophysiology and complications of uremia in experimental animals and in man. A treatment strategy is summarized.
Saborio
P
P
Nephrology Division, Department of Pediatrics and Department of Biochemistry and Molecular Biophysics, Virginia Commonwealth University's Medical College of Virginia, Richmond, Va., USA.
Hahn
S
S
Hisano
S
S
Latta
K
K
Scheinman
J I
JI
Chan
J C
JC
D000222:Adaptation, Physiological; D000818:Animals; D002648:Child; D003365:Costs and Cost Analysis; D006801:Humans; D007676:Kidney Failure, Chronic / Q000150:complications / Q000191:economics* / Q000503:physiopathology / Q000628:therapy; D014481:United States; D014511:Uremia / Q000150:complications; D014883:Water-Electrolyte Imbalance / Q000503:physiopathology