title: [Pitfalls in treatment with oral antidiabetic agents].
abstract: In the treatment of type 2 diabetes (NIDDM) we possess three groups of oral hypoglycaemic drugs: sulfonyl urea derivatives, biguanides (metformin) and alpha-glucosidase (acarbose) inhibitors. Oral treatment of diabetes has a favourable impact on the patients metabolic deviations but it involves also certain dangers and pitfalls. The side-effects of oral antidiabetics can be reduced to a minimum by respecting consequentially contraindications of administration of different preparations, knowledge of their mechanism of action and individual selection of a suitable antidiabetic for every patient.
authors.affiliation: Diabetologické centrum VFN, interní oddĕlení FP, Praha.
authors.forename: J
authors.initials: J
authors.lastname: Perusicová
mesh_terms: D020909:Acarbose; D000284:Administration, Oral; D001645:Biguanides / Q000008:administration & dosage / Q000009:adverse effects; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D013453:Sulfonylurea Compounds / Q000008:administration & dosage / Q000009:adverse effects; D014312:Trisaccharides / Q000008:administration & dosage / Q000009:adverse effects
chemical_list: D001645:Biguanides; D007004:Hypoglycemic Agents; D013453:Sulfonylurea Compounds; D014312:Trisaccharides; D020909:Acarbose