title: Lipoprotein A levels after intestinal bypass operation for morbid obesity.
abstract: BACKGROUND
  Serum Lipoprotein A [Lp(a)] is considered an independent risk factor for cardiovascular disease. Reduction of other risk factors such as serum triglycerides and serum cholesterol is seen after weight reduction but it has been difficult to demonstrate a similar reduction of Lp(a). In this study Lp(a) is studied following weight reduction after intestinal bypass surgery for obesity.
  
  
  METHODS
  A cross-sectional study was performed in which Lp(a) levels were compared between patients operated with intestinal bypass surgery for obesity (bilio-intestinal bypass) and a closely matched control group. The controls were chosen so as to correspond to the operated patients' preoperative body mass indices.
  
  
  RESULTS
  The operated group had reduced their body mass index from a mean of 42 kg/m2 to a mean of 29 kg/m2 and had a significantly lower mean serum Lp(a) level (113 mg/l, SEM 34) than controls (207 mg/l, SEM 37), p < 0.05.
  
  
  CONCLUSIONS
  Lowered Lp(a) levels are correlated to substantial weight loss following intestinal bypass surgery for obesity.
authors.affiliation: Department of Surgery, Lycksele Hospital, Sweden.
authors.forename: L
authors.initials: L
authors.lastname: Boman
authors.forename: M
authors.initials: M
authors.lastname: Ericson
mesh_terms: D000328:Adult; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007581:Jejunoileal Bypass; D017270:Lipoprotein(a) / Q000097:blood*; D008297:Male; D009767:Obesity, Morbid / Q000097:blood* / Q000601:surgery; D013997:Time Factors; D015431:Weight Loss
chemical_list: D017270:Lipoprotein(a)