title: A three-year follow-up on standard versus thin wall ePTFE grafts for hemodialysis.
abstract: OBJECTIVE
  Expanded polytetraflouroethylene (ePTFE) grafts are the most popular prosthetic grafts for hemodialysis patients in whom autogenous fistulas cannot be constructed. Long-term studies to study the durability and complication rate of the different wall configurations of ePTFE grafts have not been carried out. The primary, secondary, and cumulative patency and other complications between standard thickness (STD) and thin wall (THN) 6 mm stretch ePTFE grafts (WL Gore & Assoc, Flagstaff, AZ) was prospectively evaluated.
  
  
  METHODS
  From September 1993 to August 1995, 108 patients receiving new grafts were randomized into 2 groups: those receiving STD grafts (n = 56) or those receiving THN (n = 52) grafts. Data prospectively collected included day of first access, primary patency, interventions required, and long-term results. Infections, pseudoaneurysms, and mortality were also documented. Student's unpaired t-test was used to compare the 2 groups, and log-rank life tables were constructed and compared.
  
  
  RESULTS
  Mean follow-up examination time was 38.1 +/- 0.8 months for STD grafts and 35.1 +/- 1.0 months for THN grafts (P<.03). Longer patency was noted in the STD group of grafts (18.2 months for STD vs. 12.1 months for THN). Biographical data and complications, including pseudoaneurysm (6% vs. 5%), infection (2% vs. 3%), and mortality (22% vs. 19%), between STD and THN groups were not different statistically. Mean primary (18.2 months vs. 12.1 months), secondary (20.9 months vs. 13.7 months), and cumulative patency times (22.2 months vs. 15.2 months) for the STD group were significantly more than those for the THN group (P<.000 by log rank of life tables). Other complications were not different between groups.
  
  
  CONCLUSIONS
  Standard thickness ePTFE is the graft of choice when placing ePTFE arteriovenous grafts for hemodialysis.
authors.affiliation: Department of Surgery, University of Florida Health Science Center, Jacksonville 32209, USA.
authors.forename: B J
authors.initials: BJ
authors.lastname: Lenz
authors.forename: H C
authors.initials: HC
authors.lastname: Veldenz
authors.forename: J W
authors.initials: JW
authors.lastname: Dennis
authors.forename: S
authors.initials: S
authors.lastname: Khansarinia
authors.forename: L R
authors.initials: LR
authors.lastname: Atteberry
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017541:Aneurysm, False / Q000209:etiology; D001166:Arteriovenous Shunt, Surgical; D019917:Blood Vessel Prosthesis Implantation; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007239:Infections / Q000209:etiology; D008297:Male; D008875:Middle Aged; D011138:Polytetrafluoroethylene; D011183:Postoperative Complications; D011474:Prosthesis Design; D006435:Renal Dialysis; D014654:Vascular Patency
chemical_list: D011138:Polytetrafluoroethylene