title: Absence of relationship between Schistosoma japonicum and hepatitis B virus infection in the Dongting lake region, China.
abstract: In order to determine whether infection with Schistosoma japonicum is related to a higher rate of infection with hepatitis B virus and/or to a higher probability of HBsAg chronic carriage, a population based survey was carried out in China in which HBV markers were studied in 112 subjects with long-lasting S. japonicum infection, and 93 subjects with no S. japonicum infection 37.5% of the cases and 40.9% of controls showed no markers of HBV infection. The prevalence rate of HBsAg was 12.5% in the cases and 12.9% in the controls. For anti-HBc and anti-HBs the figures were 59.8% and 59.8%, and 27.9% and 35.0%, respectively. These data do not support the hypothesis of an interaction between infection with hepatitis B virus and S. japonicum.
authors.affiliation: The Wellcome Trust Centre for the Epidemiology of Infectious Disease, University of Oxford, UK.
authors.forename: X P
authors.initials: XP
authors.lastname: Ye
authors.forename: Y L
authors.initials: YL
authors.lastname: Fu
authors.forename: R M
authors.initials: RM
authors.lastname: Anderson
authors.forename: D J
authors.initials: DJ
authors.lastname: Nokes
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D002353:Carrier State / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D006509:Hepatitis B / Q000150:complications* / Q000453:epidemiology*; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D006801:Humans; D007223:Infant; D008875:Middle Aged; D012549:Schistosoma japonicum / Q000276:immunology; D012554:Schistosomiasis japonica / Q000150:complications* / Q000453:epidemiology*; D016036:Seroepidemiologic Studies
chemical_list: D006514:Hepatitis B Surface Antigens