Microcirculation architecture of metastases from primary ciliary body and choroidal melanomas.
OBJECTIVE
To describe the microcirculation architecture of metastatic choroidal and ciliary body melanoma.


METHODS
Histologic sections of 35 metastases from 19 primary melanomas were stained to demonstrate microcirculation.


RESULTS
The appearance of microcirculatory networks in metastases is independent of the target organ but associated with the size of the metastatic deposit (estimated coefficient = 0.5959; SE = 0.3024; P = .0488).


CONCLUSIONS
The microcirculatory patterns of primary uveal melanomas that are associated with metastatic behavior appear in foci of metastasis, regardless of the site of dissemination.
Rummelt
V
V
Department of Ophthalmology, University of Erlangen-Nürnberg.
Mehaffey
M G
MG
Campbell
R J
RJ
Pe'er
J
J
Bentler
S E
SE
Woolson
R F
RF
Naumann
G O
GO
Folberg
R
R
D002830:Choroid Neoplasms / Q000098:blood supply / Q000473:pathology*; D002924:Ciliary Body / Q000098:blood supply / Q000473:pathology*; D006801:Humans; D008545:Melanoma / Q000098:blood supply* / Q000473:pathology / Q000556:secondary*; D008833:Microcirculation