Tic disorders: new developments in Tourette syndrome and related disorders.
The constellation of motor and vocal tics and certain of the other neuropsychiatric symptoms seen in Tourette syndrome are thought to have an organic basis, although the nature of the neurobiological lesion is uncertain. The syndrome is usually familial but the presumed genetic substrate has not been identified. A number of models currently under debate include a proposed autoimmune contribution.
Robertson
M M
MM
Academic Department of Psychiatry and Behavioural Sciences, University College London Medical School, UK.
Stern
J S
JS
D001921:Brain / Q000473:pathology; D003131:Combined Modality Therapy; D020022:Genetic Predisposition to Disease; D006801:Humans; D015995:Prevalence; D016032:Randomized Controlled Trials as Topic; D005879:Tourette Syndrome / Q000453:epidemiology / Q000503:physiopathology* / Q000628:therapy; D006113:United Kingdom / Q000453:epidemiology