title: [Gonorrhea caused by fluoroquinolone resistant gonococci].
abstract: We describe a case of 4-fluoroquinolone resistant gonorrhoea where treatment failed on several occasions and where there may have been reinfections. Since 1995 peroral single dose 4-fluoroquinolones have been recommended as first preference treatment for uncomplicated gonorrhoea in Norway. However, Neisseria gonorrhoeae has a high ability to create resistance, and the emergence of 4-fluoroquinolone resistant strains is causing worldwide concern. An increasing number of 4-fluoroquinolone resistant gonococcal strains have also been observed in Norway, and the number of failures in the recommended treatment regime are increasing. It is proposed that 4-fluoroquinolone resistant strains be reported nationally.
authors.affiliation: Avdeling for sos og hiv, Ullevål sykehus, Oslo.
authors.forename: L K
authors.initials: LK
authors.lastname: Døsen
authors.forename: H
authors.initials: H
authors.lastname: Moi
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D016358:Contact Tracing; D004352:Drug Resistance, Microbial; D005260:Female; D024841:Fluoroquinolones; D006069:Gonorrhea / Q000188:drug therapy* / Q000276:immunology / Q000635:transmission; D006801:Humans; D008297:Male; D009344:Neisseria gonorrhoeae / Q000187:drug effects / Q000276:immunology; D009664:Norway
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones