title: Outcome and influence of age after infrainguinal revascularisation in critical limb ischaemia. The Swedish Vascular Registry.
abstract: OBJECTIVE
  To evaluate whether revascularisation has any influence on the mortality rate, and the impact of old age in patients with critical limb ischaemia (CLI).
  
  
  METHODS
  Analysis of Swedish Vascular Registry (Swedvasc) data.
  
  
  METHODS
  During 1987-1995, 3730 surgical and 1199 endovascular (PTA) procedures below the groin due to CLI were reported. At 1 year three groups were defined: "occluded, amputated"; "occluded, not amputated" and "patent". Survival was also calculated. Clinical outcome at 1 month and at 1 year was defined as: patient "alive, improved", "alive, not improved", "alive, amputated" and "dead". Two age groups < or = 75 years or and > or = 76 years were compared.
  
  
  RESULTS
  The mortality rate for the whole group was 5.3% at 1 month and 22.9% at 1 year, with no difference between the Surgery and PTA groups. Significantly more patients were alive and improved after surgery than after PTA at 1 month (82.3% vs. 77.7%) and at 1 year (49.6% vs. 44.3%). The amputation rate was 5.6% at 1 month and 14.4% at 1 year; 17% for diabetics. After surgery, the cumulative mortality rate did not differ between patients with a salvaged limb, irrespectively of patency of the re-construction, but was significantly higher after amputation. After PTA, only a reconstruction reported as patent was linked to the most favourable survival rate. The older patient group had a mortality rate of 6.4% at 1 month and 26.4% at 1 year, significantly higher than the younger group (3.8% and 17.6%, respectively). The amputation rate did not differ according to age. Significantly more patients were alive but not improved in the older group.
  
  
  CONCLUSIONS
  The outcome of surgery vs. PTA was similar regarding survival and amputation, but surgery resulted in a greater improvement although this might be due to selection. Older patients and those with an amputation had higher mortality rates.
authors.affiliation: Department of Surgery, Lund University, Sweden.
authors.forename: Z
authors.initials: Z
authors.lastname: Zdanowski
authors.forename: T
authors.initials: T
authors.lastname: Troeng
authors.forename: L
authors.initials: L
authors.lastname: Norgren
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000671:Amputation, Surgical / Q000706:statistics & numerical data; D000800:Angioplasty, Balloon; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D007511:Ischemia / Q000401:mortality / Q000601:surgery / Q000628:therapy*; D007866:Leg / Q000098:blood supply*; D008297:Male; D010043:Outcome and Process Assessment, Health Care; D016016:Proportional Hazards Models; D012042:Registries / Q000706:statistics & numerical data