title: Microvascular tissue transfer in a pregnant patient.
abstract: Pregnancy is a relative contraindication for elective surgery. The primary concerns are for the safety of the fetus and the mother. However, there are particular problems involving microvascular surgery due to the pregnancy-associated hypercoagulable state. The authors were presented with a 35-year woman, 20 weeks pregnant, with a degloved foot and ankle associated with an open distal tibia/fibula fracture (Gustilo IIIB). Salvage of her leg required a microvascular tissue transfer. Accordingly, a combined latissimus dorsi-serratus anterior free flap was performed with a saphenous vein graft to the popliteal vessels. The patient was hypercoagulable and there were extensive platelet clots. Her consumption of heparin was enormous. Postoperatively, she was treated with intravenous dextran for 5 days and for 17 days with intravenous heparin. After discharge, she was placed on subcutaneous heparin until she delivered a healthy baby. The flap survived and her leg was salvaged. The hypercoagulable state of pregnancy, as well as thromboprophylaxis, are discussed.
authors.affiliation: Department of Surgery, Allegheny University of the Health Sciences, MCP--Hahnemann School of Medicine, Philadelphia, Pennsylvania 19129, USA.
authors.forename: M
authors.initials: M
authors.lastname: Leong
authors.forename: M S
authors.initials: MS
authors.lastname: Granick
mesh_terms: D000328:Adult; D016512:Ankle Injuries / Q000601:surgery*; D016267:External Fixators; D005260:Female; D005360:Fibula / Q000293:injuries / Q000601:surgery; D018409:Foot Injuries / Q000601:surgery*; D005597:Fractures, Open / Q000601:surgery*; D006493:Heparin / Q000008:administration & dosage; D006801:Humans; D008866:Microsurgery / Q000379:methods; D018482:Muscle, Skeletal / Q000637:transplantation*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000517:prevention & control; D011256:Pregnancy Outcome; D012501:Saphenous Vein / Q000601:surgery; D013524:Surgical Flaps; D013924:Thrombophlebitis / Q000517:prevention & control; D013978:Tibial Fractures / Q000601:surgery*
chemical_list: D006493:Heparin