Structure of the P-type ATPases.
Electron cryocrystallography of precipitant-induced two-dimensional surface crystals of the neurospora plasma membrane H+ - ATPase and tubular crystals of the sarcoplasmic reticulum Ca(2+)-ATPase has recently yielded structure maps for these ion transporters at a resolution of about 8 A. The membrane-embedded regions of these closely related enzymes are similar, but the cytoplasmic regions appear to be significantly different.
Kühlbrandt
W
W
Max-Planck-Institut für Biophysik, Abteilung Strukturbiologie, Frankfurt am Main, Germany. kuehlbrandt@biophys.mpg.de
Auer
M
M
Scarborough
G A
GA
D000252:Calcium-Transporting ATPases / Q000737:chemistry* / Q000378:metabolism; D008958:Models, Molecular; D011487:Protein Conformation; D006180:Proton-Translocating ATPases / Q000737:chemistry* / Q000378:metabolism
D006180:Proton-Translocating ATPases; D000252:Calcium-Transporting ATPases