title: JOY: protein sequence-structure representation and analysis.
abstract: BACKGROUND
  JOY is a program to annotate protein sequence alignments with three-dimensional (3D) structural features. It was developed to display 3D structural information in a sequence alignment and to help understand the conservation of amino acids in their specific local environments.
  
  
  RESULTS
  : The JOY representation now constitutes an essential part of the two databases of protein structure alignments: HOMSTRAD (http://www-cryst.bioc.cam.ac.uk/homstrad ) and CAMPASS (http://www-cryst.bioc.cam.ac. uk/campass). It has also been successfully used for identifying distant evolutionary relationships.
  
  
  BACKGROUND
  The program can be obtained via anonymous ftp from torsa.bioc.cam.ac.uk from the directory /pub/joy/. The address for the JOY server is http://www-cryst.bioc.cam.ac.uk/cgi-bin/joy.cgi.
  
  
  BACKGROUND
  kenji@cryst.bioc.cam.ac.uk
authors.affiliation: Department of Biochemistry, University of Cambridge, Tennis Court Road, Cambridge CB2 1GA, UK. kenji@cryst.bioc.cam.ac.uk
authors.forename: K
authors.initials: K
authors.lastname: Mizuguchi
authors.forename: C M
authors.initials: CM
authors.lastname: Deane
authors.forename: T L
authors.initials: TL
authors.lastname: Blundell
authors.forename: M S
authors.initials: MS
authors.lastname: Johnson
authors.forename: J P
authors.initials: JP
authors.lastname: Overington
mesh_terms: D000595:Amino Acid Sequence; D006860:Hydrogen Bonding; D008969:Molecular Sequence Data; D011487:Protein Conformation; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry*; D016415:Sequence Alignment; D012984:Software
chemical_list: D011506:Proteins