title: [Results of the conservative surgical and irradiation treatment of 132 nonpalpable ductal carcinomas in situ of the breast].
abstract: OBJECTIVE
  Retrospective analysis of results of treatment of 132 subclinical ductal carcinomas in situ, non-palpable.
  
  
  METHODS
  Patients were treated with limited surgery and 70 Gy radiation therapy (70 Gy).
  
  
  RESULTS
  With a median follow-up of 7 years, the total recurrence rate was 6%, and the actuarial rate at 5 years 4% and at 10 years 13% at. These have no influence on recurrence on the specific actuarial survival rate which was 100% at 10 years. In spite of five infiltrating recurrences of seven, no metastasis appeared 48 months after the salvage surgery. The global rate of breast preservation was 92% at 7 years.
  
  
  CONCLUSIONS
  Therapeutic indications were developed taking into account the present analysis and a literature review (2,338 in situ ductal carcinomas, palpable or not, treated with conservative surgery, with or without adjuvant radio-therapy).
authors.affiliation: Académie méditerranéenne d'oncologie clinique, polyclinique Clairval, Marseille, France.
authors.forename: R
authors.initials: R
authors.lastname: Amalric
authors.forename: H
authors.initials: H
authors.lastname: Brandone
authors.forename: A
authors.initials: A
authors.lastname: Dubau
authors.forename: D
authors.initials: D
authors.lastname: Hans
authors.forename: J M
authors.initials: JM
authors.lastname: Brandone
authors.forename: F
authors.initials: F
authors.lastname: Robert
authors.forename: J F
authors.initials: JF
authors.lastname: Pollet
authors.forename: F
authors.initials: F
authors.lastname: Amalric
authors.forename: Y
authors.initials: Y
authors.lastname: Rouah
authors.forename: L
authors.initials: L
authors.lastname: Thomassin
authors.forename: D
authors.initials: D
authors.lastname: Giraud
authors.forename: A
authors.initials: A
authors.lastname: Henric
authors.forename: P M
authors.initials: PM
authors.lastname: Martin
authors.forename: S
authors.initials: S
authors.lastname: Romain
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D002278:Carcinoma in Situ / Q000532:radiotherapy* / Q000601:surgery*; D002285:Carcinoma, Intraductal, Noninfiltrating / Q000532:radiotherapy* / Q000601:surgery*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies; D016896:Treatment Outcome