title: MRI findings in a neonate with cerebellar agenesis.
abstract: Cerebellar agenesis is a rarely observed malformation that is frequently associated with other defects. We describe a neonate with an isolated cerebellar agenesis. In addition to the absence of recognizable cerebellar tissue, cranial magnetic resonance imaging demonstrated a hypoplastic base of the pons and absence of the normal outline of the inferior olives. Other major cerebral malformations were not found. As a developmental defect, cerebellar agenesis is heterogeneous because it occurs either as an anatomically isolated anomaly or as part of a more complex cerebral malformation. The pathogenesis and molecular basis of isolated cerebellar agenesis is unknown.
authors.affiliation: Division of Pediatric Neurology, University Hospital Gent, Belgium.
authors.forename: R N
authors.initials: RN
authors.lastname: Van Coster
authors.forename: C M
authors.initials: CM
authors.lastname: De Praeter
authors.forename: P J
authors.initials: PJ
authors.lastname: Vanhaesebrouck
authors.forename: J G
authors.initials: JG
authors.lastname: Leroy
mesh_terms: D002531:Cerebellum / Q000002:abnormalities* / Q000473:pathology*; D000013:Congenital Abnormalities / Q000175:diagnosis; D006801:Humans; D007231:Infant, Newborn; D008279:Magnetic Resonance Imaging; D011149:Pons / Q000002:abnormalities / Q000473:pathology