Brachytherapy in the presence of pyuria after pelvic irradiation for cervical cancer.
Little is known about the effects of intracavitary brachytherapy (ICB) performed in the presence of pyuria resulting from external beam pelvic irradiation for cervical cancer (CC). A retrospective study of one decade of ICB for CC showed that brachytherapy was performed in the presence of pyuria in 26 women. Twelve women without pyuria during ICB served as a control group. Antibiotic therapy was routinely administered during intracavitary application. The crude survival rate at 5 years was 39% in patients with pyuria and 42% in women without pyuria; the corresponding local recurrence rates were 23% and 17%; the serious complication rates were 12% and 0% respectively. Intracavitary brachytherapy in the presence of pyuria may have a limited adverse effect on the outcome of women with cancer of the cervix.
Ampil
F L
FL
Department of Radiology, Louisiana State University Medical Center, Shreveport 71130-3932, USA.
Bell
M C
MC
D000328:Adult; D001918:Brachytherapy / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011776:Pyuria / Q000150:complications* / Q000401:mortality; D012189:Retrospective Studies; D015996:Survival Rate; D002583:Uterine Cervical Neoplasms / Q000150:complications / Q000401:mortality / Q000532:radiotherapy*