title: Evaluation of a portable clinical analyzer in a veterinary hospital setting.
abstract: OBJECTIVE
  Evaluation of a portable clinical analyzer for determination of blood gas tensions, electrolyte and glucose concentrations, and Hct in a hospital setting.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  50 dogs, 50 cats, and 28 horses, all clinically normal.
  
  
  METHODS
  Blood samples were analyzed on a portable clinical analyzer to determine concentrations of sodium, potassium, chloride, BUN, glucose, and ionized calcium and values of Hct, pH, PCO2, and PO2. Values obtained were compared with those obtained from the same blood samples, using a standard automatic analyzer (serum sodium, potassium, chloride, BUN, and glucose concentrations), a cell counter (Hct), a blood gas analyzer (pH, PCO2, PO2), and a calcium-pH analyzer (ionized calcium). Bias (mean difference between values obtained on the same sample by different methods) and variability (SD of differences) were determined for all values. Data were also subjected to Deming regression analysis.
  
  
  RESULTS
  Correlation coefficients were > 0.90 for all values except potassium and ionized calcium concentrations. Bias and variability were within clinically acceptable limits (+/- 2 SD) for all but potassium, ionized calcium, and glucose concentrations and Hct. Species-dependent variability was observed for glucose concentration and Hct.
  
  
  CONCLUSIONS
  Most differences between values obtained with the portable clinical analyzer and standard clinical laboratory systems could be accounted for by differences in type of sample tested (blood vs serum). The portable clinical analyzer is suitable for point-of-care analysis in critical care situations and for routine blood biochemical analysis when extensive laboratory support is unavailable.
authors.affiliation: Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Ohio State University, Columbus 43210, USA.
authors.forename: D A
authors.initials: DA
authors.lastname: Grosenbaugh
authors.forename: J E
authors.initials: JE
authors.lastname: Gadawski
authors.forename: W W
authors.initials: WW
authors.lastname: Muir
mesh_terms: D000818:Animals; D015982:Bias; D001774:Blood Chemical Analysis / Q000295:instrumentation / Q000662:veterinary*; D001784:Blood Gas Analysis / Q000295:instrumentation / Q000662:veterinary*; D001786:Blood Glucose / Q000032:analysis; D002415:Cats / Q000097:blood*; D004285:Dogs / Q000097:blood*; D004573:Electrolytes / Q000097:blood; D005069:Evaluation Studies as Topic; D006400:Hematocrit / Q000295:instrumentation / Q000662:veterinary; D006736:Horses / Q000097:blood*; D019095:Point-of-Care Systems; D011446:Prospective Studies; D012016:Reference Values
chemical_list: D001786:Blood Glucose; D004573:Electrolytes