Manganese induced parkinsonism: a case report.
Manganese (Mn) intoxication is known to induce parkinsonism. Mn-induced parkinsonism preferentially affect the globus pallidus in contrast to idiopathic parkinsonism where degeneration predominantly involves the nigral pars compacta. We describe a 51-year-old man who had been occupationally exposed to Mn. He had parkinsonian features including masked face, resting tremor, and bradykinesia. He also had a cock walk and a particular propensity to fall in a backward gait. There was no sustained therapeutic response to levodopa. A fluorodopa PET scan was normal. This case indicates that Mn-induced parkinsonism can be differentiated from idiopathic parkinsonism in that the former has unique clinical features and a normal fluorodopa PET scan.
Kim
J W
JW
Department of Neurology, Dong-A University College of Medicine, Pusan, Korea. jwkim1@seunghak.donga.ac.kr
Kim
Y
Y
Cheong
H K
HK
Ito
K
K
D006801:Humans; D008297:Male; D008345:Manganese; D008875:Middle Aged; D010302:Parkinson Disease, Secondary / Q000139:chemically induced* / Q000000981:diagnostic imaging; D011859:Radiography; D014055:Tomography, Emission-Computed
D008345:Manganese