title: [Digestive hemorrhage disclosing an angiodysplasia and von Willebrand disease type 2].
abstract: The authors report a case of a 76-year-old man, with not past history of abnormal bleeding, who suffered an acute, recurrent, intestinal haemorrhage from extensive angiodysplasia of the colon. Intestinal bleeding and angiodysplasia were associated with a von Willebrand's disease. Genetic analysis showed a point mutation in arginine 611 of the mature von Willebrand's factor subunit (A1 loop) confirming a von Willebrand's disease type 2.
authors.affiliation: Département d'anesthésie-réanimation chirurgicale, hôpital de Bicêtre, France.
authors.forename: C
authors.initials: C
authors.lastname: Lefrançois
authors.forename: L
authors.initials: L
authors.lastname: Dubus
authors.forename: J
authors.initials: J
authors.lastname: Maurel
authors.forename: L
authors.initials: L
authors.lastname: Chiche
authors.forename: J M
authors.initials: JM
authors.lastname: Lavergne
authors.forename: A
authors.initials: A
authors.lastname: Borel-Derlon
mesh_terms: D000368:Aged; D016888:Angiodysplasia / Q000150:complications / Q000175:diagnosis*; D003106:Colon / Q000098:blood supply; D004241:Diverticulum, Colon / Q000150:complications; D006471:Gastrointestinal Hemorrhage / Q000209:etiology*; D006801:Humans; D008297:Male; D020125:Mutation, Missense; D010375:Pedigree; D012008:Recurrence; D014842:von Willebrand Diseases / Q000097:blood / Q000145:classification / Q000150:complications / Q000175:diagnosis* / Q000235:genetics