title: Tissue injury of Injection Gold Probe.
abstract: BACKGROUND
  The Injection Gold Probe, which incorporates an injection needle and a bipolar electrocoagulation probe, potentially offers better anchoring of the probe for electrocoagulation. This study compares the tissue injury caused by the Injection Gold Probe with or without protrusion of the needle.
  
  
  METHODS
  A 10F Injection Gold Probe was applied perpendicularly on the antrum of porcine stomach. At each site of testing, one pulse of treatment at 12 W was given for 10 seconds. The extent of tissue injury was studied under different forces of application (light touch or maximal force) and different probe conditions (needle-in, needle-out, needle-out plus 1 mL saline solution injection). Each maneuver was repeated 8 times. The depth and width of tissue injury were assessed histologically by a pathologist blinded to the treatment.
  
  
  RESULTS
  The depth and width of tissue injury did not differ significantly with needle-in, needle-out, or needle-out plus 1 mL saline solution injection on both light touch. But the tissue injury was significantly deeper and wider with maximal force applications than with light touch under the same probe condition.
  
  
  CONCLUSIONS
  The extent of tissue injury inflicted by electrocoagulation using the Injection Gold Probe is not affected by the position of the injection needle.
authors.affiliation: Department of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin.
authors.forename: L Y
authors.initials: LY
authors.lastname: Chan
authors.forename: J J
authors.initials: JJ
authors.lastname: Sung
authors.forename: F K
authors.initials: FK
authors.lastname: Chan
authors.forename: K G
authors.initials: KG
authors.lastname: To
authors.forename: J Y
authors.initials: JY
authors.lastname: Lau
authors.forename: S C
authors.initials: SC
authors.lastname: Chung
mesh_terms: D000704:Analysis of Variance; D000818:Animals; D046508:Culture Techniques; D004195:Disease Models, Animal; D004564:Electrocoagulation / Q000009:adverse effects* / Q000295:instrumentation; D006046:Gold / Q000008:administration & dosage / Q000009:adverse effects*; D015552:Injections, Intralesional / Q000009:adverse effects / Q000379:methods; D015601:Injury Severity Score; D009339:Needles; D013270:Stomach / Q000293:injuries* / Q000473:pathology / Q000601:surgery*; D013552:Swine
chemical_list: D006046:Gold