Serum interleukin-6 in congestive heart failure secondary to idiopathic dilated cardiomyopathy.
Increased serum interleukin-6 (IL-6) was associated with a higher incidence of New York Heart Association functional classes III to IV and worse left ventricular function during follow-up. Patients with elevated serum IL-6 had poor prognosis. These results reinforce the concept that increased serum IL-6 may also play an important role in disease progression.
Roig
E
E
Cardiovascular Institute, Hospital Clinic, University of Barcelona, Spain.
Orús
J
J
Paré
C
C
Azqueta
M
M
Filella
X
X
Perez-Villa
F
F
Heras
M
M
Sanz
G
G
D000328:Adult; D000368:Aged; D002311:Cardiomyopathy, Dilated / Q000276:immunology* / Q000401:mortality; D005260:Female; D005500:Follow-Up Studies; D006333:Heart Failure / Q000276:immunology* / Q000401:mortality; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction / Q000502:physiology; D011379:Prognosis; D016019:Survival Analysis; D018487:Ventricular Dysfunction, Left / Q000276:immunology / Q000401:mortality; D016277:Ventricular Function, Left / Q000502:physiology
D015850:Interleukin-6