title: Molecular cloning and sequence determination of a novel aspartic proteinase from Antarctic fish.
abstract: In the present report, we describe a novel aspartic proteinase from the liver of two Antarctic fish species. The nucleotide sequences of the cDNA obtained from the two fishes show 90% identity with each other but only 58% identity with aspartic proteinases from other sources. Sequence analysis shows features for the Antarctic enzymes which are not present in related enzymes of other organisms.
authors.affiliation: Institute of Protein Biochemistry and Enzymology, via Marconi, 10, I-80125 Naples, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Capasso
authors.forename: M
authors.initials: M
authors.lastname: Riggio
authors.forename: R
authors.initials: R
authors.lastname: Scudiero
authors.forename: V
authors.initials: V
authors.lastname: Carginale
authors.forename: G
authors.initials: G
authors.lastname: di Prisco
authors.forename: J
authors.initials: J
authors.lastname: Kay
authors.forename: P
authors.initials: P
authors.lastname: Kille
authors.forename: E
authors.initials: E
authors.lastname: Parisi
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D000864:Antarctic Regions; D016282:Aspartic Acid Endopeptidases / Q000737:chemistry*; D001483:Base Sequence; D003001:Cloning, Molecular; D005399:Fishes; D008099:Liver / Q000201:enzymology; D008969:Molecular Sequence Data; D010802:Phylogeny; D017422:Sequence Analysis, DNA; D017386:Sequence Homology, Amino Acid
chemical_list: D016282:Aspartic Acid Endopeptidases