title: Normal intrasylvian anatomical asymmetry in children with developmental language disorder.
abstract: Symmetry of posterior intrasylvian cortices (e.g., planum temporale, planum parietale) has been suggested to represent a risk factor for developmental disorders of language and reading. Using high-resolution magnetic resonance morphometry, we studied 21 right-handed children with developmental language disorder of the phonologic-syntactic type, and found normal left-right asymmetry of the planum temporale and planum parietale when compared with 21 matched controls. The planum temporale was bilaterally smaller in the affected children, a finding accounted for by their approximately 7% smaller forebrain size. Our data do not support a role of gross visible unilateral or bilateral abnormalities of posterior intrasylvian ontogenesis in this disorder.
authors.affiliation: Department of Pediatrics, Heinrich-Heine-Universität, Düsseldorf, Germany. preis@uni-duesseldorf.de
authors.forename: S
authors.initials: S
authors.lastname: Preis
authors.forename: L
authors.initials: L
authors.lastname: Jäncke
authors.forename: P
authors.initials: P
authors.lastname: Schittler
authors.forename: Y
authors.initials: Y
authors.lastname: Huang
authors.forename: H
authors.initials: H
authors.lastname: Steinmetz
mesh_terms: D000704:Analysis of Variance; D000886:Anthropometry; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007805:Language Development Disorders / Q000145:classification / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D010296:Parietal Lobe / Q000473:pathology*; D016548:Prosencephalon / Q000473:pathology; D012044:Regression Analysis; D013702:Temporal Lobe / Q000473:pathology*