title: [Ossification of pulmonary tissue].
abstract: Two cases of pulmonary ossification found in postmortems were described. The first case, a 67-year-old stop-smoker with systemic hypertension died of a ruptured atherosclerotic aneurysm of the abdominal aorta. A well-defined subpleural mass (52 mm in max. dimension) was composed of monotonous mature trabecular osseous tissue with two focuses of cartilage up to 500 microns. There was no evidence of occluded blood supply and chronic passive congestion in the pulmonary parenchyma. A diagnosis of mesenchymoma (osteohamartoma) with the predominance of osseous tissue was made. The second case, a 72-year-old man non-smoker died of urosepsis. There were no pulmonary symptoms in patient's previous history. A well-defined ovoid mass (25 mm in diameter) was subpleurally located. Microscopically, it was formed of small nodules of mature lamellar bone together with branching bony deposits of trabecular character. Moreover, there were multiple smaller focuses scattered in the distant pulmonary tissue having appearance of nodular ossification. The evidence of chronic thromboembolic pulmonary disease together with ossification in microscopy permits the possibility that the nodular ossification may develop from pulmonary scarring or hemorrhagies as a late consequence of the thromboembolic pulmonary disease.
authors.affiliation: Fingerlandův ústav patologie LF UK, Hradec Králové.
authors.forename: M
authors.initials: M
authors.lastname: Resl
authors.forename: F
authors.initials: F
authors.lastname: Langr
authors.forename: I
authors.initials: I
authors.lastname: Farová
authors.forename: J
authors.initials: J
authors.lastname: Kudr
authors.forename: A
authors.initials: A
authors.lastname: Kohout
mesh_terms: D000368:Aged; D006801:Humans; D008168:Lung / Q000473:pathology*; D008297:Male; D009999:Ossification, Heterotopic / Q000473:pathology*