title: Highly destructive perianal Crohn's disease.
abstract: This article reports a case of highly destructive perianal Crohn's disease in a 15-year-old boy who presented with fecal impaction and incontinence. Both upper and lower gastrointestinal tract endoscopy were unrevealing. Treatment with intravenous prednisolone and broad-spectrum antibiotics supplemented by enteral feeding with an elemental diet resulted in prompt recovery. However, healing of his perianal lesions began only after a diverting colostomy. Awareness of this uncommon entity is important because prompt recognition can lead to early institution of appropriate treatment and avoid further morbidity.
authors.affiliation: Department of Pediatrics, Children's Hospital of New Orleans, Louisiana, USA.
authors.forename: A K
authors.initials: AK
authors.lastname: Shetty
authors.forename: J
authors.initials: J
authors.lastname: Udall
authors.forename: E
authors.initials: E
authors.lastname: Schmidt-Sommerfeld
mesh_terms: D000293:Adolescent; D000890:Anti-Infective Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001004:Anus Diseases; D002939:Ciprofloxacin / Q000627:therapeutic use; D003125:Colostomy; D003424:Crohn Disease / Q000150:complications* / Q000601:surgery / Q000628:therapy; D004750:Enteral Nutrition; D005244:Fecal Impaction / Q000209:etiology; D005242:Fecal Incontinence / Q000209:etiology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008795:Metronidazole / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D008795:Metronidazole; D002939:Ciprofloxacin; D011239:Prednisolone