Identification and in situ hybridization mapping of a mouse Tpd52l1 (D53) orthologue to chromosome 10A4-B2.
We report the identification of a mouse cDNA Tpd52l1 (tumor protein D52-like 1), which represents the first demonstrated orthologue of the human TPD52L1 (alias D53) gene, a member of the breast carcinoma-associated TPD52 (alias D52) gene family. In situ hybridization mapping located the Tpd52l1 gene to chromosome 10A4-10B2. Since the TPD52L1 gene is found at human chromosome 6q22-->q23, the mouse and human TPD52L1 loci are syntenically conserved.
Byrne
J A
JA
Children's Medical Research Institute, Wentworthville, NSW Australia. JennifeB@nch.edu.au
Mattei
M G
MG
Basset
P
P
Gunning
P
P
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D001943:Breast Neoplasms / Q000235:genetics; D002874:Chromosome Mapping; D005260:Female; D015723:Gene Library; D006801:Humans; D008297:Male; D051379:Mice / Q000235:genetics*; D008969:Molecular Sequence Data; D005810:Multigene Family; D009363:Neoplasm Proteins / Q000737:chemistry / Q000235:genetics*; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D013234:Stem Cells
D009363:Neoplasm Proteins; C114751:TPD52 protein, human; C486416:TPD52L1 protein, human; C486415:Tpd52 protein, mouse