title: [Clinical, hemodynamic and angiographic results of total cavo-pulmonary connection].
abstract: The aim of the study was to assess the short and medium term results of total cavo-pulmonary connection based on analysis of the functional status, the cavo-pulmonary circulation and the surgical techniques, and the hepatic consequences. Fifteen patients with congenital defects beyond repair were treated by total cavo-pulmonary connection at Tours between March 1st 1992 and July 30th 1996. There were 12 children (mean age: 6.3 years) and 3 adults aged 25 to 28. Results were assessed by clinical examination, hepatic function tests and cardiovascular investigations including right heart catheterisation with angiography in 14 patients. There were no fatalities. Seven patients were in functional Class I and 8 in Class II at medium term (average follow-up of 33 months). Hepatic function was mildly abnormal in all patients with an increase in serum bilirubin and gamma GT, and a decrease in the coagulation factors. The mean pressures in the atrial channel were 12 mmHg (9-16 mmHg), in the superior vena 13.2 mmHg (10-18 mmHg), in the right pulmonary artery 9.5 mmHg (7-15 mmHg) and 11.6 mmHg (8-16 mmHg) in the left pulmonary artery. Significant residual stenosis of a pulmonary branch was observed in 2 cases. The cavo-pulmonary anastomoses were out of line, one from the other, in all cases. The atrial channel was tubular in 9 cases and dilated with slight stagnation of the contrast medium in its inferior region in 5 cases. Total cavo-pulmonary connection transformed the clinical status of these patients but was associated with minor abnormalities of liver function. The quality of the cavo-pulmonary circulation and the surgical anastomoses was estimated to be satisfactory in the majority of cases.
authors.affiliation: Service de pédiatrie A, CHU, hôpital Clocheville, Tours.
authors.forename: A C
authors.initials: AC
authors.lastname: Jimenez
authors.forename: P
authors.initials: P
authors.lastname: Neville
authors.forename: C
authors.initials: C
authors.lastname: Chamboux
authors.forename: R
authors.initials: R
authors.lastname: Crenn
authors.forename: M C
authors.initials: MC
authors.lastname: Vaillant
authors.forename: M
authors.initials: M
authors.lastname: Marchand
authors.forename: A
authors.initials: A
authors.lastname: Chantepie
mesh_terms: D000328:Adult; D000790:Angiocardiography; D002648:Child; D005260:Female; D006325:Heart Atria / Q000000981:diagnostic imaging; D018610:Heart Bypass, Right; D006330:Heart Defects, Congenital / Q000000981:diagnostic imaging* / Q000601:surgery; D006439:Hemodynamics; D006801:Humans; D008297:Male; D011651:Pulmonary Artery / Q000000981:diagnostic imaging; D016896:Treatment Outcome; D014683:Vena Cava, Superior / Q000000981:diagnostic imaging