title: [Late-occurrence hemolytic anemia after mitral valve bioprosthesis. 2 cases].
abstract: The authors report the cases of two patients admitted to hospital for investigation of haemolytic anaemia. Both had undergone, 10 and 12 years previously, mitral valve replacement with a Ionescu-Shiley bioprosthesis. In both cases, in the absence of signs of cardiac failure, Doppler echocardiography showed mitral regurgitation. The association of haemolytic anaemia and dysfunction of the bioprosthesis led to redux valve replacement and correction of the anaemia. Haemolytic anaemia was the presenting sign of bioprosthetic valve dysfunction requiring replacement of the prosthesis. This complication is common with mechanical valve prostheses but much more rare in bioprosthetic valves.
authors.affiliation: Service de médecine interne A, Tours.
authors.forename: R
authors.initials: R
authors.lastname: Piquemal
authors.forename: L
authors.initials: L
authors.lastname: Fauchier
authors.forename: C
authors.initials: C
authors.lastname: Regimbeau
authors.forename: D
authors.initials: D
authors.lastname: Babuty
authors.forename: P
authors.initials: P
authors.lastname: Neville
authors.forename: J P
authors.initials: JP
authors.lastname: Renard
mesh_terms: D000368:Aged; D000743:Anemia, Hemolytic / Q000209:etiology*; D001705:Bioprosthesis / Q000009:adverse effects*; D015150:Echocardiography, Doppler; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008943:Mitral Valve / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology; D011474:Prosthesis Design; D011475:Prosthesis Failure; D012086:Reoperation