title: Mini radial keratotomy reduces ocular integrity. Axial compression in a postmortem porcine eye model.
abstract: OBJECTIVE
  This study aimed to examine ocular rupture force in pig eyes after "minimally invasive radial keratotomy" (MRK) and standard radial keratotomy (SRK).
  
  
  METHODS
  Experimental study.
  
  
  METHODS
  A total of 71 pairs of pig eyes (51 control eyes) were examined.
  
  
  METHODS
  An axial-torsional Materials Testing System (MTS, Eden Prairie, MN) was used to apply blunt force to the corneal surface. A force transducer measured the rupture forces in control eyes and in eyes with MRK or SRK. Five groups of paired eyes were compared: 2.0-mm MRK versus control (N = 12), 3.5-mm MRK versus control (N = 21), 6.5-mm SRK versus control (N = 18), SRK versus 3.5-mm MRK versus 2.0-mm MRK (N = 10).
  
  
  METHODS
  Ocular rupture force (newtons) was measured.
  
  
  RESULTS
  The mean rupture force in newtons was 746.3 for control eyes, 514.2 for 2.0-mm MRK, 353.1 for 3.5-mm MRK, and 246.2 for SRK. Analysis of variance showed a statistically significant difference (P < or = 0.04) between paired comparisons.
  
  
  CONCLUSIONS
  The MRK and SRK significantly weakened ocular integrity compared with control eyes not operated on. MRK required significantly more force to rupture than SRK. MRK eyes, however, ruptured at 50% to 70% of the force required to rupture eyes not operated on. Any patient considering radial keratotomy should be counseled about the risk of greater ocular damage in trauma.
authors.affiliation: Jones Eye Institute, Department of Ophthalmology, University of Arkansas for Medical Sciences, Little Rock.
authors.forename: T L
authors.initials: TL
authors.lastname: Steinemann
authors.forename: T C
authors.initials: TC
authors.lastname: Baltz
authors.forename: B L
authors.initials: BL
authors.lastname: Lam
authors.forename: M
authors.initials: M
authors.lastname: Soulsby
authors.forename: R C
authors.initials: RC
authors.lastname: Walls
authors.forename: H H
authors.initials: HH
authors.lastname: Brown
mesh_terms: D000818:Animals; D003315:Cornea / Q000503:physiopathology / Q000601:surgery*; D065306:Corneal Injuries; D005131:Eye Injuries / Q000150:complications* / Q000503:physiopathology; D007646:Keratotomy, Radial / Q000009:adverse effects*; D008954:Models, Biological; D011312:Pressure; D012421:Rupture; D013529:Surgical Wound Dehiscence / Q000209:etiology* / Q000503:physiopathology; D013552:Swine; D014949:Wounds, Nonpenetrating / Q000150:complications* / Q000503:physiopathology