title: Combination laser conization as treatment of microinvasive carcinoma of the uterine cervix.
abstract: During the period June 1985 to August 1992 combination laser conization was considered definite therapy in 41 patients with microinvasive carcinoma of the cervix. Selection criteria for conservative, fertility-saving therapy were: invasion 3 mm or less, no lymphovascular involvement and horizontal spread of 7 mm or less. After treatment patients were followed for 5 to 12 years, mean follow-up 81 months, and mean number of examination was 10. In one cases, adenocarcinoma in situ was diagnosed during follow-up. In all other cases persistent or recurrent disease was not diagnosed during follow-up. By thorough histopathologic evaluation and strict criteria for selection of patients, it was possible to perform conservative treatment with no observed risk of undertreatment. Combination laser conization was a useful treatment modality. A follow-up regimen based on colposcopy and cytology proved sufficient.
authors.affiliation: Department of Obstetrics and Gynecology, Aalborg Hospital, Denmark.
authors.forename: E S
authors.initials: ES
authors.lastname: Andersen
authors.forename: K
authors.initials: K
authors.lastname: Nielsen
authors.forename: B
authors.initials: B
authors.lastname: Pedersen
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002277:Carcinoma / Q000473:pathology / Q000601:surgery*; D019092:Conization; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D053685:Laser Therapy; D008875:Middle Aged; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*