title: [Possibilities and limits of electron beam tomography].
abstract: Electron beam CT, which does not require mechanical movement of an X-ray tube, has a temporal resolution which exceeds that of conventional computed tomography by a factor of about ten. Axial images of the heart can be acquired within 50 to 100 ms with a spatial resolution below 0.5 mm2 and permit precise visualization of all cardiac structures. ECG-triggered acquisition of 30 to 40 axial images (3 mm slice thickness) in a short inspiratory breathhold allows one to sample a 3-dimensional volume data set which covers the complete heart. Overall acquisition times are approximately 30 to 50 seconds. While electron beam CT in general permits a complete cardiac investigation, including morphology, function, and perfusion, the method's most important application is non-invasive imaging of the coronary arteries. Without contrast enhancement, coronary calcifications by EBCT currently constitutes the most sensitive non-invasive marker for the presence even of very early forms of coronary atherosclerosis. Intravenous injection of contrast agent during image acquisition additionally permits the selective visualization of the coronary artery lumen and detection of significant stenoses. This method is especially well suited in the follow-up of coronary interventions and coronary bypass grafting. Breathhold and movement artifacts, superposition of coronary arteries and veins, as well as severe coronary calcifications currently constitute the method's main problems. In spite of these limitations, electron beam CT has been shown to permit clinically valuable non-invasive investigations of the coronary arteries, which may be further refined as technology progresses.
authors.affiliation: Medizinische Klinik II mit Poliklinik Friedrich-Alexander-Universität Erlangen-Nürnberg.
authors.forename: W
authors.initials: W
authors.lastname: Moshage
authors.forename: S
authors.initials: S
authors.lastname: Achenbach
authors.forename: K
authors.initials: K
authors.lastname: Bachmann
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017023:Coronary Angiography / Q000295:instrumentation; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000000981:diagnostic imaging* / Q000601:surgery; D005260:Female; D006083:Graft Occlusion, Vascular / Q000000981:diagnostic imaging; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D008297:Male; D008875:Middle Aged; D012680:Sensitivity and Specificity; D015898:Tomography Scanners, X-Ray Computed