title: When placebo controlled trials are essential and equivalence trials are inadequate.
authors.affiliation: Pain Research and Nuffield Department of Anaesthetics, University of Oxford, Oxford Radcliffe Hospital, The Churchill, Headington, Oxford OX3 7LJ. martin.tramer@hcugh.ch
authors.forename: M R
authors.initials: MR
authors.lastname: Tramèr
authors.forename: D J
authors.initials: DJ
authors.lastname: Reynolds
authors.forename: R A
authors.initials: RA
authors.lastname: Moore
authors.forename: H J
authors.initials: HJ
authors.lastname: McQuay
mesh_terms: D000932:Antiemetics / Q000627:therapeutic use; D035061:Control Groups; D018849:Controlled Clinical Trials as Topic; D003627:Data Interpretation, Statistical; D019317:Evidence-Based Medicine; D006801:Humans; D009325:Nausea / Q000517:prevention & control; D017294:Ondansetron / Q000627:therapeutic use; D010919:Placebos; D018570:Risk Assessment; D014839:Vomiting / Q000517:prevention & control
chemical_list: D000932:Antiemetics; D010919:Placebos; D017294:Ondansetron