title: Evidence of Epstein-Barr virus in lymphoepithelioma-like carcinoma of the uterine cervix: a case report.
abstract: Lymphoepithelioma-like carcinoma of the uterine cervix is very rare. A 71-year-old woman, who had cervical cancer stage IB, presented lymphoepithelioma-like carcinoma pathologically. The neoplasm revealed an undifferentiated, nonkeratinizing carcinoma, which contained prominent vesicular nucleoli histologically. Epstein-Barr virus (EBV) DNA and HPV-16 DNA were demonstrated in cancer cells when using polymerase chain reaction. The patient underwent a radical hysterectomy with bilateral pelvic lymph node dissection and bilateral salpingooophorectomy. Her postoperative course was uneventful. The literature and pathologic findings are reviewed and discussed.
authors.affiliation: Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: L H
authors.initials: LH
authors.lastname: Tseng
authors.forename: C J
authors.initials: CJ
authors.lastname: Tseng
authors.forename: Y K
authors.initials: YK
authors.lastname: Soong
authors.forename: S
authors.initials: S
authors.lastname: Hsueh
authors.forename: C C
authors.initials: CC
authors.lastname: Pao
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000821:virology*; D004279:DNA, Viral / Q000032:analysis; D005260:Female; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D016133:Polymerase Chain Reaction; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000821:virology*
chemical_list: D004279:DNA, Viral