title: Ossified and de novo cavernous malformations in the same patient.
abstract: We report the case of a 44-year-old patient with a MRI scan showing a newly developed cavernoma after two highly calcified lesions had been excised surgically. Six other cavernous malformations had been followed by MR imaging over a 2-year period. The coexistence of the two extremes of cavernous malformations in terms of lesions development--de novo and ossified lesions has not been reported previously and has implications for both the follow-up and the natural history of these malformations. The potential for developing new cavernous malformations persists and does not seem to be related to the evolutional stage of pre-existing lesions. It is suggested that these patients need to be followed up by MRI on a regular basis.
authors.affiliation: Department of Neurosurgery, Nordstadt Hospital, Hannover, Germany. rosahl@t-online.de
authors.forename: S K
authors.initials: SK
authors.lastname: Rosahl
authors.forename: P
authors.initials: P
authors.lastname: Vorkapic
authors.forename: R
authors.initials: R
authors.lastname: Eghbal
authors.forename: H
authors.initials: H
authors.lastname: Ostertag
authors.forename: M
authors.initials: M
authors.lastname: Samii
mesh_terms: D000328:Adult; D002114:Calcinosis; D006392:Hemangioma, Cavernous / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D002538:Intracranial Arteriovenous Malformations / Q000150:complications / Q000175:diagnosis / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D009999:Ossification, Heterotopic