title: Synthesis and pharmacology of a new AMPA-kainate receptor agonist with potent convulsant activity.
authors.affiliation: Istituto di Chimica Farmaceutica e Tossicologica, Università di Milano, v.le Abruzzi, 42-20131 Milano, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Conti
authors.forename: M
authors.initials: M
authors.lastname: De Amici
authors.forename: G
authors.initials: G
authors.lastname: De Sarro
authors.forename: T B
authors.initials: TB
authors.lastname: Stensbøl
authors.forename: H
authors.initials: H
authors.lastname: Bräuner-Osborne
authors.forename: U
authors.initials: U
authors.lastname: Madsen
authors.forename: C
authors.initials: C
authors.lastname: De Micheli
mesh_terms: D000818:Animals; D003292:Convulsants / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology / Q000633:toxicity; D018690:Excitatory Amino Acid Agonists / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology / Q000633:toxicity; D007555:Isoxazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology / Q000633:toxicity; D051379:Mice; D011758:Pyrroles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology / Q000633:toxicity; D018091:Receptors, AMPA / Q000819:agonists*; D018092:Kainic Acid Receptors / Q000819:agonists*; D012640:Seizures / Q000139:chemically induced; D013237:Stereoisomerism; D013329:Structure-Activity Relationship
chemical_list: D003292:Convulsants; D018690:Excitatory Amino Acid Agonists; D007555:Isoxazoles; D011758:Pyrroles; D018091:Receptors, AMPA; D018092:Kainic Acid Receptors; C114806:3a,5,6,6a-tetrahydro-4H-pyrrolo(3,4-d)isoxazole-3,4-dicarboxylic acid