[The tissue reaction to acrylic plastics modified by supercritical extraction with carbon dioxide].
The process of extraction of admixtures from acryl plastic widely used in dentistry by means of supercritical carbon dioxide (sc-CO2) was studied and effects of extraction conditions on biocompatibility and toxicity of resultant materials assessed, sc-CO2 effectively purified the specimens from toxic compounds (monomers and low-molecular oligomers, methylmethacrylate, dichloroethane) and notably improved the biocompatability of polymer implants. Tissue reaction to ethacryl and protacryl depends on the degree of implant polymerization and duration of extraction of toxic substances from polymer.
Volozhin
A I
AI
Shekhter
A B
AB
Karakov
K G
KG
Sukhanov
Iu P
IuP
Gavril'chak
A V
AV
Popov
V K
VK
Antonov
E N
EN
Karrot
M
M
D000180:Acrylic Resins / Q000032:analysis / Q000302:isolation & purification / Q000633:toxicity*; D000818:Animals; D002245:Carbon Dioxide; D003764:Dental Materials / Q000032:analysis / Q000302:isolation & purification / Q000633:toxicity*; D004343:Drug Implants; D008401:Gas Chromatography-Mass Spectrometry; D007202:Indicators and Reagents; D008422:Materials Testing; D051381:Rats; D012867:Skin / Q000187:drug effects* / Q000473:pathology; D013997:Time Factors
D000180:Acrylic Resins; D003764:Dental Materials; D004343:Drug Implants; D007202:Indicators and Reagents; D002245:Carbon Dioxide