title: [Treatment of male infertility after oncologic therapy: preventive autologous sperm preservation versus testicular biopsy and oocyte fertilization with testicular spermatozoa].
abstract: The prognosis of oncological therapy of some malignancies is favourable. Unfortunately the majority of young patients remain sterile. Sperm cryopreserved before treatment was successfully used in IVF-ICSI (in vitro fertilization-intracytoplasmic sperm injection) cycles. Testicular biopsy (TESE) was performed after successful oncological treatment in three men without previous sperm cryopreservation. No spermatozoa were found for oocyte fertilization. TESE could not ensure sperm recovery in all patients after oncological treatment. Sperm cryopreservation should be highly recommended to all patients before any treatment is offered.
authors.affiliation: FERTIMED-centrum pro lécbu neplodnosti, Olomouc.
authors.forename: A
authors.initials: A
authors.lastname: Sobek
authors.forename: Z
authors.initials: Z
authors.lastname: Mucha
authors.forename: K
authors.initials: K
authors.lastname: Hrbková
authors.forename: J
authors.initials: J
authors.lastname: Pernicka
authors.forename: F
authors.initials: F
authors.lastname: Zát'ura
authors.forename: J
authors.initials: J
authors.lastname: Vodicka
authors.forename: M
authors.initials: M
authors.lastname: Dokoupilová
authors.forename: J
authors.initials: J
authors.lastname: Scheinar
mesh_terms: D015925:Cryopreservation; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007248:Infertility, Male / Q000209:etiology* / Q000628:therapy; D008297:Male; D011247:Pregnancy; D012099:Reproductive Techniques; D012189:Retrospective Studies; D012662:Semen Preservation; D013737:Testis / Q000166:cytology*