title: Influence of growth mode and sucrose on susceptibility of Streptococcus sanguis to amine fluorides and amine fluoride-inorganic fluoride combinations.
abstract: This study evaluated the susceptibility to amine fluorides (AmFs) of planktonic and biofilm cultures of Streptococcus sanguis grown with and without sucrose. Cultures were incubated with AmFs (250 mg of fluoride liter-1) for 1 min. The susceptibility of biofilms was less than that of the planktonic form and was further decreased by growth in the presence of sucrose.
authors.affiliation: Departments of Microbiology, Eastman Dental Institute for Oral Health Care Sciences, University of London, London WC1X 8LD, United Kingdom.
authors.forename: J V
authors.initials: JV
authors.lastname: Embleton
authors.forename: H N
authors.initials: HN
authors.lastname: Newman
authors.forename: M
authors.initials: M
authors.lastname: Wilson
mesh_terms: D000588:Amines / Q000494:pharmacology*; D000818:Animals; D018441:Biofilms / Q000187:drug effects* / Q000254:growth & development; D002327:Cariostatic Agents / Q000494:pharmacology; D003470:Culture Media; D005459:Fluorides / Q000494:pharmacology*; D006863:Hydrogen-Ion Concentration; D008826:Microbial Sensitivity Tests; D013298:Streptococcus sanguis / Q000187:drug effects* / Q000254:growth & development; D013395:Sucrose / Q000378:metabolism*; D017967:Zinc Compounds / Q000494:pharmacology
chemical_list: D000588:Amines; D002327:Cariostatic Agents; D003470:Culture Media; D017967:Zinc Compounds; D013395:Sucrose; C038904:zinc fluoride; D005459:Fluorides