Computer-based image analysis of nucleoli in prostate carcinoma.
The authors have evaluated the nucleoli in 37 cases of prostatic carcinoma. The increase in Gleason's grade 1 correlated with an increase in the percentage of nucleolated nuclei. The increase in the percentage of bi- and trinucleolated nuclei was accompanied by a decrease of the uninucleated nuclei. The values of morphometrical parameters studied in the individual nucleoli (area, perimeter, diameters) increased in Gleason grade 2 tumors as compared with grade 1 tumors. In tumors higher grades there was, however, a progressive decrease of these values.
Olinici
C D
CD
Department of Morphopathology, University of Medicine and Pharmacy.
Crişan
D
D
Olinici
C I
CI
Vaida
M
M
D002466:Cell Nucleolus / Q000473:pathology*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008297:Male; D011471:Prostatic Neoplasms / Q000473:pathology* / Q000601:surgery