title: Radiocontrast-induced nephropathy.
abstract: Radiocontrast-induced nephropathy (RCIN) is a common cause of acute renal failure. It results from an ischemic injury to the medullary portion of the kidney secondary to intense renal vasoconstriction. Patients with pre-existing renal insufficiency, diabetes, congestive heart failure, taking certain medications, and exposed to large volumes of high osmolar contrast are at increased risk of developing RCIN. Prophylaxis of high-risk patients by careful hydration and avoidance of exacerbating factors can minimize the incidence of RCIN.
authors.affiliation: Harvard Medical School, and the Renal Division, Beth Israel Deaconess Medical Center, Boston, MA, USA.
authors.forename: R
authors.initials: R
authors.lastname: Solomon
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced* / Q000517:prevention & control; D003287:Contrast Media / Q000009:adverse effects*; D006801:Humans
chemical_list: D003287:Contrast Media