title: Propagation and localization of Wnt signaling.
abstract: Cellular mechanisms for the transport and localization of Wnt signaling components are important for the propagation, distribution, and polarization of Wnt signals in embryonic tissues. Wnt signals are distributed through tissues by vesicular transport of Wnt proteins, localized in embryos by directed transport of cytoplasmic Wnt-signaling components, and propagated asymmetrically during cell division.
authors.affiliation: Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA. b-gumbiner@ski.mskcc.org
authors.forename: B M
authors.initials: BM
authors.lastname: Gumbiner
mesh_terms: D000818:Animals; D017173:Caenorhabditis elegans / Q000196:embryology; D002455:Cell Division; D004330:Drosophila / Q000196:embryology; D029721:Drosophila Proteins; D006023:Glycoproteins / Q000378:metabolism; D011518:Proto-Oncogene Proteins / Q000378:metabolism*; D015398:Signal Transduction; D051153:Wnt Proteins; D051155:Wnt1 Protein; D029867:Xenopus Proteins; D014982:Xenopus laevis / Q000196:embryology / Q000378:metabolism; D029961:Zebrafish Proteins
chemical_list: D029721:Drosophila Proteins; D006023:Glycoproteins; D011518:Proto-Oncogene Proteins; D051153:Wnt Proteins; D051155:Wnt1 Protein; D029867:Xenopus Proteins; D029961:Zebrafish Proteins; C074622:wg protein, Drosophila; C512785:wnt11b protein, Xenopus