title: Problem of amputations in patients with newly diagnosed diabetes mellitus.
abstract: A reduction of 50% or more in diabetes-related amputations is a primary target of the St Vincent Declaration. This is thought to be achievable because both primary and secondary preventative healthcare strategies are effective in reducing the incidence of diabetic foot ulceration and progression to amputation. Unfortunately there is a group who cannot benefit from preventative health care, that is, newly diagnosed diabetic patients with already established severe complications. Using our population-based district diabetes information system we investigated, during the period 1 January 1992 to 31 December 96, the incidence and prevalence of lower extremity amputations (LEAs) and the proportion occurring in patients newly or recently diagnosed as having diabetes. Seventy-nine diabetic patients (59 male, 20 female) were recorded as having had 94 LEAs, the incidence of diabetes-related LEA being 475 per 100,000 diabetic patient-years. Of these LEAs 16 (20.2%) were performed within 1 year of diabetes being diagnosed. This study highlights an appreciable and previously unrecognized problem: patients presenting with established complications of diabetes who cannot benefit from secondary preventative healthcare. These patients pose a potential obstacle to achieving targets for reductions in diabetes-related amputations.
authors.affiliation: Diabetes Centre, Hope Hospital, Manchester, UK.
authors.forename: J P
authors.initials: JP
authors.lastname: New
authors.forename: D
authors.initials: D
authors.lastname: McDowell
authors.forename: E
authors.initials: E
authors.lastname: Burns
authors.forename: R J
authors.initials: RJ
authors.lastname: Young
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000671:Amputation, Surgical; D003922:Diabetes Mellitus, Type 1 / Q000150:complications*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D017719:Diabetic Foot / Q000453:epidemiology / Q000209:etiology / Q000601:surgery*; D003929:Diabetic Neuropathies / Q000150:complications; D004739:England / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007511:Ischemia / Q000150:complications; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects; D013997:Time Factors; D014456:Ulcer / Q000150:complications