title: [Radiotherapy of cancer of the anal canal. 15 years experience at the Lyon civil hospices and brief review of the literature].
abstract: OBJECTIVE
  Retrospective analysis of a series of 287 anal canal carcinomas seen during a 15-year period in the Department of Radiotherapy Oncology of Hospices Civils de Lyon.
  
  
  METHODS
  Between 1980 and 1995, 287 patients were managed in the radiotherapy department of Hospices Civils de Lyon. In 25 cases, the patients were referred for recurrence. Post or preoperative irradiation was performed in 12 and 23 cases. Palliative treatment was given to 15 cases and simple follow-up in 7 cases. Radiotherapy was given to 205 patients. In 71 cases irradiation alone and in 134 concomitant radiochemotherapy was given.
  
  
  RESULTS
  The 5-year overall survival of the group treated by radiotherapy (205 patients) was 71.5% and the 10 year-overall survival was 60.8%. The specific survival at 5 and 10 years was 81.9% and 74.7% respectively. At 5 years the overall survival was 78% for the group treated by concomitant radiochemotherapy and 60% for the group treated by irradiation alone.
  
  
  CONCLUSIONS
  Radiotherapy is the standard treatment for anal canal carcinoma. Radiochemotherapy seems to improve results in advanced cases. The best irradiation of technique has yet to be defined.
authors.affiliation: Service de Radiothérapie-Oncologie, Centre Hospitalier Lyon Sud, Pierre-Bénite.
authors.forename: J P
authors.initials: JP
authors.lastname: Gérard
authors.forename: E
authors.initials: E
authors.lastname: Morignat
authors.forename: P
authors.initials: P
authors.lastname: Romestaing
authors.forename: F
authors.initials: F
authors.lastname: Mornex
authors.forename: J M
authors.initials: JM
authors.lastname: Ardiet
authors.forename: L
authors.initials: L
authors.lastname: Ayzac
authors.forename: P
authors.initials: P
authors.lastname: Roy
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001005:Anus Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D005260:Female; D006738:Hospices; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010166:Palliative Care; D018714:Radiotherapy, Adjuvant; D012004:Rectal Neoplasms / Q000401:mortality / Q000473:pathology / Q000532:radiotherapy*; D015996:Survival Rate