[Modulation of the long-term memory by delayed administration of the nootropic agent L-pyroglutamyl-D-alaninamide during spaced and massed training of rats].
L-pyroglutamyl-D-alanine amide significantly enhanced freezing response in the group of rats with massed training and reduced it in the group with spaced training. The control animals revealed a higher freezing response with the spaced training. No differences occurred between the groups in a cue test.
Vysotskiĭ
A L
AL
P. K. Anokhin Institute of Normal Physiology of the Russian Acad. Med. Sci., Moscow, Russia.
Vysotskiĭ
D L
DL
Gudasheva
T A
TA
Ostrovskaia
R U
RU
Anokhin
K V
KV
D000161:Acoustic Stimulation; D000818:Animals; D003213:Conditioning, Psychological / Q000187:drug effects* / Q000502:physiology; D004151:Dipeptides / Q000494:pharmacology*; D005239:Fear / Q000187:drug effects* / Q000502:physiology; D008568:Memory / Q000187:drug effects* / Q000502:physiology; D018697:Nootropic Agents / Q000494:pharmacology*; D011761:Pyrrolidonecarboxylic Acid / Q000031:analogs & derivatives; D051381:Rats; D017208:Rats, Wistar; D012018:Reflex / Q000187:drug effects* / Q000502:physiology
D004151:Dipeptides; D018697:Nootropic Agents; C054344:pyroglutamylalanine amide; D011761:Pyrrolidonecarboxylic Acid