Unusual accumulation of glycogen in liver parenchymal cells in a patient with anorexia nervosa.
Anorexia nervosa is an eating disorder characterized by a fear of weight gain and a preoccupation with body image. Although hepatic involvement has been reported in patients with anorexia nervosa, the mechanism is not fully understood. We describe a patient with anorexia nervosa with liver function abnormalities. Light and electron microscopic observations revealed a remarkable accumulation of glycogen in hepatocytes. These results suggest that adaptive responses to starvation may alter carbohydrate metabolism in patients with anorexia nervosa.
Komuta
M
M
Second Department of Medicine, Kurume University School of Medicine.
Harada
M
M
Ueno
T
T
Uchimura
Y
Y
Inada
C
C
Mitsuyama
K
K
Sakisaka
S
S
Sata
M
M
Tanikawa
K
K
D000328:Adult; D000856:Anorexia Nervosa / Q000378:metabolism* / Q000473:pathology; D005260:Female; D006801:Humans; D008099:Liver / Q000378:metabolism / Q000648:ultrastructure; D008112:Liver Glycogen / Q000378:metabolism*
D008112:Liver Glycogen