Aino virus antigen in brain lesions of a naturally aborted bovine fetus.
A bovine fetus aborted at 187 days of gestation was serologically and immunohistopathologically examined. Serum and cerebrospinal fluid samples had high titers of virus-neutralizing antibody for Aino virus. A severe necrotizing encephalopathy was noted. Aino virus antigen was demonstrated in neuroglial cells within the brain lesion. The destruction of developing neuronal cells appeared to be a significant feature of the pathogenesis of lesions due to Aino virus infection in the central nervous system.
Noda
Y
Y
Ryochiku Livestock Hygiene Service Center, Kurume, Fukuoka, Japan.
Uchinuno
Y
Y
Shirakawa
H
H
Nagasue
S
S
Nagano
N
N
Ohe
R
R
Narita
M
M
D000034:Abortion, Veterinary / Q000473:pathology / Q000821:virology*; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood / Q000134:cerebrospinal fluid; D000956:Antigens, Viral / Q000032:analysis*; D001927:Brain Diseases / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D002044:Bunyaviridae Infections / Q000473:pathology / Q000662:veterinary* / Q000821:virology; D002417:Cattle; D002418:Cattle Diseases / Q000473:pathology / Q000821:virology*; D005260:Female; D005333:Fetus / Q000821:virology; D007124:Immunoenzyme Techniques / Q000662:veterinary; D009457:Neuroglia / Q000473:pathology / Q000821:virology; D011247:Pregnancy; D012840:Simbu virus / Q000276:immunology*
D000914:Antibodies, Viral; D000956:Antigens, Viral