The efficacy of an intraoral fluoride-releasing system in irradiated head and neck cancer patients: a preliminary study.
This study compared the anticaries effectiveness of an intraoral fluoride-releasing system, or IFRS, with a standard regimen of daily application of a 1.1 percent neutral sodium fluoride gel in custom trays. Caries protection in subjects in the IFRS group was comparable to that in subjects in the 1.1 percent neutral sodium fluoride group. The subjects all had head or neck cancer and had received radiation therapy, but no more recently than three months before taking part in the study. Overall, IFRS devices were well-tolerated and patient satisfaction was high. The IFRS appears to offer several advantages over the daily application of fluoride gels in custom trays.
Meyerowitz
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Eastman Department of Dentistry, University of Rochester, N.Y. 14642, USA.
Watson
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GE
D000284:Administration, Oral; D000328:Adult; D002327:Cariostatic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D003731:Dental Caries / Q000000981:diagnostic imaging / Q000517:prevention & control*; D016503:Drug Delivery Systems; D005260:Female; D005459:Fluorides / Q000008:administration & dosage*; D005460:Fluorides, Topical / Q000008:administration & dosage / Q000627:therapeutic use; D005500:Follow-Up Studies; D005782:Gels; D006258:Head and Neck Neoplasms / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D010865:Pilot Projects; D011859:Radiography; D017213:Root Caries / Q000000981:diagnostic imaging / Q000517:prevention & control; D016037:Single-Blind Method; D012969:Sodium Fluoride / Q000008:administration & dosage / Q000627:therapeutic use
D002327:Cariostatic Agents; D005460:Fluorides, Topical; D005782:Gels; D012969:Sodium Fluoride; D005459:Fluorides