New antiepileptic drugs and psychopathology.
The literature on the effects of anticonvulsant drugs on behaviour is reviewed, with particular attention to the new agents. Positive psychotropic effects, and negative influences on behaviour are noted. The latter include depression and psychoses. The drugs most involved seem to be those with GABAergic properties, and the role of forced normalisation is discussed.
Trimble
M R
MR
Institute of Neurology, London, UK.
D000927:Anticonvulsants / Q000009:adverse effects*; D003863:Depression / Q000139:chemically induced*; D004569:Electroencephalography / Q000187:drug effects; D004827:Epilepsy / Q000188:drug therapy*; D018682:GABA Agents / Q000009:adverse effects; D006801:Humans; D011605:Psychoses, Substance-Induced
D000927:Anticonvulsants; D018682:GABA Agents