Halawanones A-D, new polycyclic quinones from a marine-derived streptomycete
Four new quinone-containing metabolites, halawanones A-D (1-4), have been isolated along with the known compound nanaomycin D (5) from liquid cultures of a streptomycete obtained from a sediment sample collected in the estuarine environment at the mouth of Halawa stream, Oahu. The structures of the new compounds were determined through the interpretation of spectral data. The absolute stereochemistries were determined using a combination of CD and NMR.
Department of Chemistry and Biochemistry, Utah State University, Logan, Utah 84322-0300, and Department of Chemistry, University of Hawaii at Manoa, Honolulu, Hawaii 96822, USA.
PW
Ford
M
Gadepalli
BS
Davidson