[Treatment of newly diagnosed patients with infiltrative and disseminated pulmonary tuberculosis].
To enhance the efficiency of treatment in new cases of infiltrative and disseminated destructive pulmonary tuberculosis, an intermittent (twice daily) regimen of intravenous dropwise administration of three drugs (isoniazid, rifampicin, PASK) was proposed. The immediate results of clinical observations suggest that intermittent 3-drug intravenous chemotherapy supplemented by collapse therapy in some indicated cases, provides a high control over the therapy, sparing drug load, good tolerance, and rather high efficiency: elimination of destructions in 81.4% (mean 4.2 months), cessation of bacterial isolation in 88.9% in the early (2.2 months) period.
Ursov
I G
IG
Krasnov
V A
VA
B1tashova
V A
VA
Kudelia
O A
OA
Volkova
Zh A
ZhA
Gromyko
N I
NI
Borovinskaia
T A
TA
D000293:Adolescent; D000328:Adult; D000904:Antibiotics, Antitubercular / Q000008:administration & dosage; D000995:Antitubercular Agents / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D007538:Isoniazid / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D012293:Rifampin / Q000008:administration & dosage; D013997:Time Factors; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
D000904:Antibiotics, Antitubercular; D000995:Antitubercular Agents; D007538:Isoniazid; D012293:Rifampin
Lechenie vpervye vyiavlennykh bol'nykh rasprostranennym infil'trativnym i disseminirovannym tuberkulezom legkikh.