Pemphigus vulgaris associated with transient acanthosis nigricans like lesion.
A patient with pemphigus vulgaris was treated with predonisolone and cyclosporin. At the sites of healing erosions, hyperkeratotic, hyperpigmented plaques developed; they were clinically and histologically similar to acanthosis nigricans. These lesions regressed after a few months. This case and others described in the literature suggest that such dermatoses might be caused by immunologically as well as mechanically mediated epidermal injury.
Department of Dermatology, Jichi Medical School, Tochigi-ken, Japan.
K
K
Usui
A
A
Kondo
H
H
Nakagawa
D000052:Acanthosis Nigricans / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010392:Pemphigus / Q000150:complications* / Q000188:drug therapy / Q000473:pathology