Complete nucleotide sequence analysis of a Western Pacific dengue-1 virus strain.
We have determined the complete nucleotide sequence and the deduced amino acid polypeptide sequence of the genome of a dengue-1 (DEN-1) virus strain isolated from a patient on Nauru in the Western Pacific in 1974 (West Pac 74). The complete genome is 10,735 nucleotides in length and contains a single long open reading frame of 10,176 nucleotides encoding a polyprotein of 3392 amino acids. When compared to DEN-1 Singapore S275/90, the nucleotide and amino acid sequence homology are 94% and 97.8%, respectively.
Infectious Diseases Department, Naval Medical Research Institute, Bethesda, Maryland 20889-5607, USA. PURI@NMRIPO.NMRI.NNMC.NAVY.MIL
B
B
Puri
W
W
Nelson
K R
KR
Porter
E A
EA
Henchal
C G
CG
Hayes
D000595:Amino Acid Sequence; D001483:Base Sequence; D018076:DNA, Complementary / Q000737:chemistry / Q000235:genetics*; D003716:Dengue Virus / Q000737:chemistry / Q000235:genetics*; D008969:Molecular Sequence Data; D016366:Open Reading Frames / Q000235:genetics; D010139:Pacific Islands; D017422:Sequence Analysis, DNA; D014764:Viral Proteins / Q000235:genetics
D018076:DNA, Complementary; D014764:Viral Proteins