Insights into the pathogenesis of psoriasis and psoriatic arthritis.
Psoriasis and its related arthritis are chronic inflammatory disorders affecting predominantly the skin and synovium. Although their etiology remains to be established, multiple factors seem to play important roles in their pathogenesis. These environmental (eg, infectious agents and trauma), genetic, and immunologic factors are reviewed in this article.
Department of Medicine, Louisiana State University School of Medicine, New Orleans 70112-2822, USA.
L R
LR
Espinoza
R
R
van Solingen
M L
ML
Cuellar
J
J
Angulo
D015535:Arthritis, Psoriatic / Q000209:etiology* / Q000276:immunology / Q000503:physiopathology; D006680:HLA Antigens / Q000235:genetics; D006801:Humans; D007249:Inflammation; D011565:Psoriasis / Q000209:etiology* / Q000235:genetics / Q000276:immunology
D006680:HLA Antigens