[Idiopathic CD4+ T-lymphocyte deficiency: the clinical evolution of a case].
The case of a patient with Salmonella arizonae sepsis, esophageal candidiasis, and a low CD4+ T lymphocyte count is presented. Follow-up continued for over 2 years after the patient was discharged from the hospital, and his clinical course and clinical-immunological examinations are described. After a period of several years during which the patient had recurrent acute infectious episodes, he improved markedly after cholecystectomy and toilette of the gingival inlets for severe parodontopathy. His CD4+ T cell count increased although it remained below normal values. This case points to possible hypothesis that chronic infective foci may further compromise the immune system when a congenital functional or numerical CD4+ T cell deficit is present.
Cattedra di Medicina Interna III, Università degli Studi La Sapienza di Roma.
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D000208:Acute Disease; D002177:Candidiasis / Q000150:complications / Q000175:diagnosis; D002908:Chronic Disease; D018450:Disease Progression; D004941:Esophagitis / Q000175:diagnosis / Q000209:etiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010510:Periodontal Diseases / Q000175:diagnosis / Q000209:etiology; D012008:Recurrence; D012480:Salmonella Infections / Q000150:complications / Q000175:diagnosis; D012476:Salmonella arizonae; D018344:T-Lymphocytopenia, Idiopathic CD4-Positive / Q000175:diagnosis* / Q000209:etiology
Deficit idiopatico di linfociti T CD4+: evoluzione clinica di un caso.