Effects of a hydrated sodium calcium aluminosilicate (T-Bind) on mycotoxicosis in young broiler chickens.
Experiments were conducted to determine the ability of a hydrated sodium calcium aluminosilicate (T-Bind) sorbent to reduce the toxicity of aflatoxins (AF) or T-2 toxin in male broiler chickens from day of hatch to 21 d of age. In Experiment 1, the sorbent was added at 0.250 or 0.375% to diets containing AF at 5 or T-2 toxin at 8 mg/kg of diet. When compared with controls, AF reduced BW gain by 27% and T-2 toxin reduced BW gain by 17%. The addition of the sorbent at 0.250 or 0.375%, in the absence of added mycotoxins, did not alter the performance of the chicks. The sorbent reduced the toxic effects of 5 mg AF/kg of diet on BW gain by 43% but did not significantly diminish the toxic effects of 8 mg T-2 toxin/kg of diet. The decreased efficiency of feed utilization and the increased relative organ weights caused by AF were significantly diminished to differing degrees by the sorbent. Oral lesions caused by T-2 toxin were not affected by the sorbent. In Experiment 2, the sorbent was added at 0.80% to a diet containing 8 mg T-2 toxin/kg of diet. The sorbent did not diminish the toxic effects of T-2 toxin when added at 0.80% of the diet. These data demonstrate that this specific sorbent can provide protection against the toxicity of AF, but not T-2 toxin, in young broiler chicks.
Kubena
L F
LF
USDA, Agricultural Research Service, Food Animal Protection Research Laboratory, College Station, Texas 77845, USA. kubena@usda.tamu.edu
Harvey
R B
RB
Bailey
R H
RH
Buckley
S A
SA
Rottinghaus
G E
GE
D000348:Aflatoxins / Q000032:analysis / Q000493:pharmacokinetics; D000538:Aluminum Silicates / Q000008:administration & dosage / Q000494:pharmacology*; D000821:Animal Feed; D000818:Animals; D002645:Chickens; D008297:Male; D015651:Mycotoxicosis / Q000517:prevention & control / Q000662:veterinary*; D011201:Poultry Diseases / Q000382:microbiology / Q000517:prevention & control*; D014018:Tissue Distribution; D015430:Weight Gain / Q000187:drug effects
D000348:Aflatoxins; D000538:Aluminum Silicates; C087965:sodium calcium aluminosilicate, hydrated