Acetazolamide in the treatment of acute mania. A case report.
Several antiepileptic drugs are also being used in affective disorders. There are some hints that also the carbonic anhydrase inhibitor acetazolamide might be useful in the treatment of bipolar affective disorder. We report a 39-year-old male patient with a history of bipolar affective disorder who presented with his second manic episode. Acetazolamide was added to a low dose of valproic acid and to perazine. A marked decrease of the BRMAS score was achieved. The implications of this case are discussed.
Brandt
C
C
Department of Psychiatry, University of Freiburg and University of Munich, Germany.
Grunze
H
H
Normann
C
C
Walden
J
J
D000086:Acetazolamide / Q000627:therapeutic use*; D000328:Adult; D018692:Antimanic Agents / Q000627:therapeutic use*; D001714:Bipolar Disorder / Q000188:drug therapy*; D002257:Carbonic Anhydrase Inhibitors / Q000627:therapeutic use*; D006801:Humans; D008297:Male
D018692:Antimanic Agents; D002257:Carbonic Anhydrase Inhibitors; D000086:Acetazolamide