From "magic bullet" to "specially engineered shotgun loads": the new genetics and the need for individualized pharmacotherapy.
Steady progress in the identification of human pharmacogenetic variants and new discoveries of disease susceptibility genes makes the old notion of one disease/one drug untenable. Advances in the ability to rapidly identify these variants, when coupled with appropriate drug delivery systems, should revolutionize pharmacotherapy.
Erickson
R P
RP
Angel Charity for Children-Wings for Genetic Research, Steele Memorial Children's Research Center, Department of Pediatrics, University of Arizona College of Medicine, Tucson 85724-5073, USA. erickson@peds.arizona.edu
D020022:Genetic Predisposition to Disease; D015316:Genetic Therapy / Q000379:methods / Q000639:trends; D006801:Humans; D010597:Pharmacogenetics / Q000379:methods* / Q000639:trends