Immunotherapy and experimental approaches for metastatic melanoma.
This article reviews the clinical investigations involving recombinant cytokines (either alone or in combination with adoptive immunotherapy, toxicity reduction agents, or cytotoxic chemotherapy), vaccines, monoclonal antibodies or antibody conjugates, and gene therapy. These various approaches are reviewed for their current and potential roles in curing metastatic melanoma.
Atkins
M B
MB
Melanoma Program, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
D000912:Antibodies, Neoplasm / Q000276:immunology / Q000627:therapeutic use; D019496:Cancer Vaccines / Q000276:immunology / Q000627:therapeutic use; D006801:Humans; D007167:Immunotherapy; D008545:Melanoma / Q000276:immunology* / Q000628:therapy*; D009362:Neoplasm Metastasis; D012878:Skin Neoplasms / Q000276:immunology* / Q000628:therapy*
D000912:Antibodies, Neoplasm; D019496:Cancer Vaccines