[Factor VIII inhibitor appearing in women during delivery].
Factor VIII inhibitor is rare, but very serious postpartum complication. Bleeding diathesis caused by this inhibitor is called acquired haemophilia. Three women with postpartum inhibitor to factor VIII and life threatening bleeding were described. In two patients bleeding was controlled by treatment with high doses of human and porcine factor VIII concentrates. One patient died presenting uncontrolled haemorrhagic diathesis. This work presents the problems of the diagnosis, treatment and also the elimination of the factor VIII inhibitor.
Kliniki Chirurgicznej Instytutu Hematologii i Transfuzjologii w Warszawie.
W
W
Kucharski
R
R
Scharf
J M
JM
Ziemski
W
W
Jaśkowiak
S
S
Lopaciuk
S
S
Sikora
P
P
Siekierski
D000328:Adult; D005169:Factor VIII / Q000502:physiology*; D005260:Female; D006467:Hemophilia A / Q000175:diagnosis*; D006801:Humans; D007744:Obstetric Labor Complications; D011247:Pregnancy
D005169:Factor VIII
Inhibitor czynnika VIII pojawiajacy sie u kobiet w okresie okołoporodowym.