Herbal medicine for periodontal diseases.
Traditional Chinese Medicine (TCM) is a treasure-house which has shown miraculous clinical effects. It has aroused tremendous interests in elucidating its mechanisms both in China and abroad. This paper presents a review of published articles on the effects and mechanisms of herbal medicine on periodontal disease. Specifically, two modifications of an ancient compound prescription were serially studied, Guchiwan (Tooth-firming pills) and Guchigao (Tooth-firming extract). Some in vitro studies have shown suppressive effects of various herbal extracts on bone resorption by isolated osteoclasts. TCM should be intensively studied for their possible use in periodontics.
Department of Periodontology, School of Stomatology, Beijing Medical University, China.
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Cao
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Sun
D000818:Animals; D000890:Anti-Infective Agents / Q000627:therapeutic use; D001862:Bone Resorption / Q000473:pathology / Q000503:physiopathology; D002478:Cells, Cultured; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D008516:Medicine, Chinese Traditional; D010010:Osteoclasts / Q000187:drug effects; D010510:Periodontal Diseases / Q000188:drug therapy*; D010518:Periodontitis / Q000188:drug therapy; D008517:Phytotherapy; D010936:Plant Extracts / Q000494:pharmacology / Q000627:therapeutic use
D000890:Anti-Infective Agents; D004365:Drugs, Chinese Herbal; D010936:Plant Extracts