Neoclerodane diterpenoids from teucrium massiliense
A reinvestigation of the diterpene metabolites of Teucrium massiliense L. allowed the isolation of four new neoclerodane derivatives, teumassilenins A-D, together with all the diterpenoids previously reported as constituents of this plant. The structures of the new compounds (1-4) were established by chemical and spectroscopic means. A plausible biogenetic relationship between several of these substances is briefly discussed, and some unpublished physical and spectroscopic data of the previously known diterpenoid teumassin (5) are now reported.
Dipartimento di Chimica Organica, Universita di Palermo, Via Archirafi 20, I-90123 Palermo, Italy, and Instituto de Quimica Organica, Consejo Superior de Investigaciones Cientificas (CSIC), Juan de la Cierva 3, E-28006 Madrid, Spain.
G
Fontana
MP
Paternostro
G
Savona
B
Rodriguez
de la Torre MC