Deep breathing and awake apnoea in a patient who had recurrent hypoxaemia and hypercapnia without sleep apnoea.
A 21 yr old with deep breathing and awake apnoea, who had recurrent hypoxaemia and hypercapnia without sleep apnoea, was presented. Although the organic abnormality responsible for the breathing disturbance was not found, administration of acetazolamide facilitated several breaths between sighs, and the patient's hypoxaemia with hypercapnia improved. Some patients who have abnormalities in the cortical control of breathing that cannot be detected by present methods of examination may experience some improvement in breathing with the administration of chemical stimulants such as acetazolamide.
Dept of Clinical Physiology, Chest Disease Research Institute, Kyoto University, Japan.
K
K
Chin
Y
Y
Oku
K
K
Nishimura
M
M
Ohi
D000086:Acetazolamide / Q000627:therapeutic use; D000328:Adult; D001049:Apnea / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D006935:Hypercapnia / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D000860:Hypoxia / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D008297:Male; D012119:Respiration; D012129:Respiratory Function Tests; D012891:Sleep Apnea Syndromes / Q000175:diagnosis; D016896:Treatment Outcome
D000086:Acetazolamide