Pain caused by herpes zoster infection.
Postherpetic neuralgia (PHN) is a neuropathic pain disorder that occurs most often in the elderly. This painful condition is uniquely suited for clinical research, resulting in an emerging understanding of the pathophysiology of the persistent pain. Until recently, only the tricyclic antidepressants proved effective for PHN. Controlled trials of a wide variety of therapeutic strategies are in progress or have been recently completed.
Cluff
R S
RS
Department of Neurology, Pain Clinical Research Center, University of California, San Francisco 94115, USA.
Rowbotham
M C
MC
D000700:Analgesics / Q000009:adverse effects / Q000627:therapeutic use; D000929:Antidepressive Agents, Tricyclic / Q000009:adverse effects / Q000627:therapeutic use; D002986:Clinical Trials as Topic; D006562:Herpes Zoster / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D009437:Neuralgia / Q000175:diagnosis* / Q000188:drug therapy; D010147:Pain Measurement
D000700:Analgesics; D000929:Antidepressive Agents, Tricyclic