[Testosterone response (in blood serum and seminal plasma) to anti-estrogen stimulation test in fertile men and patients with disturbances of spermatogenesis].
Testosterone concentrations in blood serum and seminal plasma in basic conditions and in antiestrogen test (Clostilbegyt 100 mg daily for 10 days) were evaluated for 21 fertile males, 24 males with normogonadotropic oligozoospermia and 25 azoospermia patients. Average output testosterone concentration in blood serum of the analysed groups did not differ statistically significantly, but in antiestrogen test it increased statistically significantly. Average output testosterone concentration in semen plasma in fertile men was 0.66 +/- 0.26 ng/ml (about 10 times lower than in blood serum) and idiopatic oligozoospermic patients had a half of this number. Clostilbegyt test caused increase of testosterone concentration in semen plasma in all groups (except for normospermic) what proves the relation of hormonal reactions observed in blood serum with the ones in semen plasma.
Medraś
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Katedry i Kliniki Endokrynologii AM we Wrocławiu.
Kiełkiewicz
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D000328:Adult; D004965:Estrogen Antagonists; D006801:Humans; D008297:Male; D009845:Oligospermia / Q000175:diagnosis*; D012661:Semen / Q000737:chemistry; D013739:Testosterone / Q000032:analysis / Q000097:blood*
D004965:Estrogen Antagonists; D013739:Testosterone
Reakcja ze strony testosteronu na bodziec przeciwestrogenowy w surowicy oraz plazmie nasienia u osób płodnych i z zaburzeniami spermatogenezy.