[Secondary kidney amyloidosis and mucoviscidosis].
BACKGROUND
Due to the improvement in cystic fibrosis management, life expectancy has risen; on the other hand, longer survival has led to new complications, including secondary renal amyloidosis, which has been so far very uncommonly reported.


METHODS
Secondary nephropathic amyloidosis was seen in two 25-year and 22-year-old adults with cystic fibrosis. Both had developed recurrent pulmonary infections due to Pseudomonas aeruginosa over several years. One patient died after 2 years of progressive kidney failure.


CONCLUSIONS
Severe renal insufficiency due to secondary amyloidosis may complicate the course of cystic fibrosis and become the main prognosis factor in adults.
Guillot
M
M
Service de pédiatrie et centre de soins mucoviscidose, centre hospitalier général, Lisieux, France.
Drut-Desombre
B
B
Amiour
M
M
Aljazayri
Z
Z
Eckart
P
P
Dominique
S
S
Grateau
G
G
D000293:Adolescent; D000328:Adult; D000686:Amyloidosis / Q000473:pathology*; D001706:Biopsy; D002648:Child; D003550:Cystic Fibrosis / Q000473:pathology*; D017809:Fatal Outcome; D005500:Follow-Up Studies; D006801:Humans; D007674:Kidney Diseases / Q000473:pathology*; D007676:Kidney Failure, Chronic / Q000473:pathology; D007678:Kidney Glomerulus / Q000473:pathology; D008297:Male
Amylose rénale secondaire et mucoviscidose.