[Association of Biermer's anemia and gastric carcinoid tumors].
BACKGROUND
The occurrence of gastric carcinoid tumors during the cure of pernicious anemia has been reported in the literature. Concerning a new case, we review physiopathological data of this infrequent association.


METHODS
We report the case of a 47-year-old women with pernicious anemia in which gastroscopy found two small tumors developed from enterochromaffin-like cells.


CONCLUSIONS
These tumors are usually latent and developed from enterochromaffin-like cells. The pathologic and histologic diagnosis is based on positive chromogranin A immunomarking. The physiopathological mechanism studies are in favour of the predominant part of hypergastrinemia following achlorhydria. Usually, evolution is benign and surgical or endoscopic resection recommended.
Boudray
C
C
Service de médecine interne, centre hospitalier Lyon-Sud, Pierre-Bénite, France.
Grange
C
C
Durieu
I
I
Levrat
R
R
D000752:Anemia, Pernicious / Q000150:complications* / Q000188:drug therapy; D002276:Carcinoid Tumor / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D053379:Chromogranin A; D002864:Chromogranins / Q000032:analysis; D019861:Enterochromaffin-like Cells / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D005773:Gastroscopy; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D013997:Time Factors; D014805:Vitamin B 12 / Q000627:therapeutic use
D053379:Chromogranin A; D002864:Chromogranins; D014805:Vitamin B 12
Association d'une anémie de Biermer et de tumeurs carcinoïdes gastriques.