Familial mediterranean fever and acute myocardial infarction secondary to coronary vasculitis.
OBJECTIVE
We report a case study to elucidate the pathogenesis of polyarteritis nodosa (PAN) type vasculitis, a rare complication of familial mediterranean fever (FMF).


RESULTS
A woman with amyloidosis complicating FMF underwent a cadaveric renal transplantation and 5 years later suffered an acute myocardial infarction secondary to an isolated coronary vasculitis.


CONCLUSIONS
The histopathological findings of the vasculitis were not in keeping with PAN. We postulated that the pathogenesis of vasculitis in FMF is different from that of the classic PAN and might be similar to the mechanism of the serosal inflammation.
Department of Pathology, Hospital 12 de Octubre, Madrid, Spain.
R
R
Serrano
M A
MA
Martínez
A
A
Andrés
J M
JM
Morales
R
R
Samartin
D000328:Adult; D000686:Amyloidosis / Q000150:complications / Q000473:pathology; D003331:Coronary Vessels; D010505:Familial Mediterranean Fever / Q000209:etiology* / Q000473:pathology; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007668:Kidney / Q000473:pathology; D009203:Myocardial Infarction / Q000150:complications* / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D010488:Polyarteritis Nodosa / Q000150:complications / Q000473:pathology*; D013154:Spleen / Q000473:pathology