Psammocarcinoma with an aggressive course.
BACKGROUND
Psammocarcinoma is an unusual variant of serous cystadenocarcinoma characterized by heavy deposits of psammoma bodies. This disease has been suggested to be similar to carcinomas of low malignant potential in its indolent clinical course. We present this case report of an aggressive course of this disease to alert others that psammocarcinoma may not always follow a benign course.


METHODS
A 66-year-old woman underwent staging laparotomy for bilateral ovarian cystadenofibromata with rare foci of borderline serous tumors and several small bowel peritoneal surface nodules showing infiltrating psammocarcinoma. She was not recommended for adjuvant therapy because of the previously reported indolent course of this disease. Eighteen months later she represented with small bowel obstruction and underwent an exploratory laparotomy that demonstrated diffuse recurrence of the psammocarcinoma.


CONCLUSIONS
Psammocarcinoma may have a more aggressive course than has been suggested. Patients with this disease should have optimal tumor debulking. There may be a role for adjuvant therapy in its treatment.
Department of Obstetrics and Gynecology, UCLA School of Medicine, Los Angeles, California 90027, USA. spoggi@ucla.edu
S H
SH
Poggi
R E
RE
Bristow
R K
RK
Nieberg
J S
JS
Berek
D000368:Aged; D018284:Cystadenocarcinoma, Serous / Q000601:surgery; D005260:Female; D006801:Humans; D007414:Intestinal Neoplasms / Q000601:surgery; D009364:Neoplasm Recurrence, Local; D010051:Ovarian Neoplasms / Q000601:surgery; D010534:Peritoneal Neoplasms / Q000601:surgery