Interstrain variation in the deoxynucleotide composition of Cryptococcus neoformans: nucleotide composition of Cryptococcus neoformans.
The deoxynucleotide (dNMP) composition of ten strains of C. neoformans was analysed by 32P-labelling and two-dimensional thin-layer chromatography. This technique is very sensitive for detecting rare deoxynucleotide adducts and analogues (minor bases) in DNA. The results indicate considerable variation among strains in DNA nucleotide composition.
Podwall
D
D
Albert Einstein College of Medicine, Bronx, New York, USA.
Yador
E
E
Miller
S
S
Pena
J
J
Franzot
S P
SP
Lipetz
J
J
Casadevall
A
A
Steinberg
J J
JJ
D001345:Autoradiography; D001482:Base Composition; D001938:Brazil; D002855:Chromatography, Thin Layer / Q000379:methods; D003455:Cryptococcus neoformans / Q000235:genetics* / Q000302:isolation & purification; D004271:DNA, Fungal / Q000737:chemistry* / Q000235:genetics / Q000302:isolation & purification; D003854:Deoxyribonucleotides / Q000032:analysis*; D014644:Genetic Variation; D016919:Meningitis, Cryptococcal / Q000134:cerebrospinal fluid / Q000382:microbiology; D015203:Reproducibility of Results; D013045:Species Specificity
D004271:DNA, Fungal; D003854:Deoxyribonucleotides