Cystoid macular edema associated with latanoprost in aphakic and pseudophakic eyes.
OBJECTIVE
To describe four patients who developed cystoid macular edema shortly after onset of treatment with latanoprost.


METHODS
Retrospective review of medical records of patients with open-angle glaucoma who developed cystoid macular edema shortly after starting latanoprost.


RESULTS
The use of topical latanoprost was temporally related to the development of cystoid macular edema in four patients (six eyes; two aphakic eyes and four pseudophakic eyes). Cystoid macular edema resolved in all patients after latanoprost was discontinued.


CONCLUSIONS
Cystoid macular edema is a potential complication of latanoprost therapy. Further observations are needed to determine if the risk of cystoid macular edema is limited to or greatest in patients who are pseudophakic or aphakic.
Department of Ophthalmology, University of South Florida, Tampa, USA. rsayyala@hotmail.com
R S
RS
Ayyala
D A
DA
Cruz
C E
CE
Margo
L E
LE
Harman
S E
SE
Pautler
D M
DM
Misch
J A
JA
Mines
D W
DW
Richards
D000368:Aged; D000369:Aged, 80 and over; D001036:Aphakia, Postcataract / Q000150:complications*; D005902:Glaucoma, Open-Angle / Q000188:drug therapy; D006801:Humans; D000077338:Latanoprost; D008269:Macular Edema / Q000139:chemically induced*; D008297:Male; D009883:Ophthalmic Solutions; D011461:Prostaglandins F, Synthetic / Q000009:adverse effects*; D019591:Pseudophakia / Q000150:complications*; D012189:Retrospective Studies; D014792:Visual Acuity
D009883:Ophthalmic Solutions; D011461:Prostaglandins F, Synthetic; D000077338:Latanoprost