Cicatricial pemphigoid (benign mucous membrane pemphigoid).
Cicatricial pemphigoid is a chronic mucocutaneous bullous condition. It is a heterogenous autoimmune disease, characterized by the production of autoantibodies against basement membrane zone antigens. The target antigens in cicatricial pemphigoid appear to be lamina lucida proteins involved in human keratinocyte adhesion to extracellular matrix. Cicatricial pemphigoid primarily affects persons older than 40 years and appears to have a 2:1 predilection for women, without racial or geographic bias.
Terezhalmy
G T
GT
Department of Dentistry, Cleveland Clinic Foundation, Ohio 44195, USA.
Bergfeld
W F
WF
D000328:Adult; D000890:Anti-Infective Agents / Q000627:therapeutic use; D003622:Dapsone / Q000627:therapeutic use; D003937:Diagnosis, Differential; D016107:Epidermolysis Bullosa Acquisita / Q000175:diagnosis; D005260:Female; D005447:Fluocinonide / Q000627:therapeutic use; D005455:Fluorescent Antibody Technique; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010348:Patient Care Team; D010390:Pemphigoid, Benign Mucous Membrane / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D010391:Pemphigoid, Bullous / Q000175:diagnosis; D011241:Prednisone / Q000627:therapeutic use; D012744:Sex Ratio; D012872:Skin Diseases, Vesiculobullous / Q000175:diagnosis
D000890:Anti-Infective Agents; D005938:Glucocorticoids; D005447:Fluocinonide; D003622:Dapsone; D011241:Prednisone