The nephrotoxicity of new and old immunosuppressive drugs.
The above snapshot of the relevant literature on chronic Cyclosporine and Tacrolimus nephropathy indicate fertile areas for further study. The reader is referred to recent reviews for a more in-depth analysis of this problem (2).
Division of Nephrology, Hypertension, and Clinical Pharmacology, Oregon Health Sciences University, Portland 97201, USA.
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Bennett
D000208:Acute Disease; D000818:Animals; D002908:Chronic Disease; D016572:Cyclosporine / Q000009:adverse effects / Q000633:toxicity; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000633:toxicity; D007668:Kidney / Q000187:drug effects*; D007674:Kidney Diseases / Q000139:chemically induced*; D016030:Kidney Transplantation; D011379:Prognosis; D020123:Sirolimus / Q000009:adverse effects / Q000633:toxicity; D016559:Tacrolimus / Q000009:adverse effects / Q000633:toxicity
D007166:Immunosuppressive Agents; D016572:Cyclosporine; D020123:Sirolimus; D016559:Tacrolimus