Linkage mapping of Lims1l, the murine homolog of the human LIM domain gene PINCH, to mouse chromosome 10.
The human LIM domain gene LIMS1 was used to identify a mouse homolog. The resulting mouse sequence was used to identify a polymorphism by SSCP analysis. Linkage studies performed in the EUCIB backcross placed Lims1l on the proximal portion of mouse Chromosome 10. This localisation makes it an interesting candidate for the deafness mutant, waltzer (v).
Action Research Laboratory for Fetal Development, Division of Paediatrics, Obstetrics and Gynaecology, Imperial College of Science, Technology and Medicine, Queen Charlotte's and Chelsea Hospital, London, UK.
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S
Abu-Hayyeh
J
J
Eddleston
J N
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Murdoch
M
M
Tham
A J
AJ
Copp
P
P
Stanier
D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D002874:Chromosome Mapping; D004268:DNA-Binding Proteins / Q000235:genetics*; D008040:Genetic Linkage; D006239:Haplotypes; D018398:Homeodomain Proteins / Q000235:genetics*; D006801:Humans; D060588:LIM Domain Proteins; D060850:LIM-Homeodomain Proteins; D008565:Membrane Proteins; D051379:Mice; D014157:Transcription Factors
D048868:Adaptor Proteins, Signal Transducing; D004268:DNA-Binding Proteins; D018398:Homeodomain Proteins; C085473:LHX1 protein, human; D060588:LIM Domain Proteins; D060850:LIM-Homeodomain Proteins; C088088:LIMS1 protein, human; C499523:Lhx1 protein, mouse; C490232:Lims1 protein, mouse; D008565:Membrane Proteins; D014157:Transcription Factors