[Lead intoxication and amyotrophic lateral sclerosis].
A seventy-six-year-old patient developed a bulbar form of amyotrophic lateral sclerosis, after chronic lead intoxication from drinking water. Treatment with 2,3 dimercaptosuccinic acid was administered for six months and had no effect on clinical course. We discuss the imputability of lead as a possible etiological factor.
Service de Neurologie, CHU Dupuytren, Limoges.
P
P
Couratier
P
P
Bernet-Bernady
T
T
Truong
E
E
Lagrange
P M
PM
Preux
G
G
Lachatre
J M
JM
Vallat
D000368:Aged; D000690:Amyotrophic Lateral Sclerosis / Q000139:chemically induced / Q000503:physiopathology*; D002614:Chelating Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007855:Lead Poisoning / Q000150:complications* / Q000188:drug therapy / Q000209:etiology; D004113:Succimer / Q000627:therapeutic use*; D016896:Treatment Outcome; D014881:Water Supply
D002614:Chelating Agents; D004113:Succimer
Intoxication au plomb et sclérose latérale amyotrophique.