[Acute alveolitis after using a waterproofing aerosol: apropos of 2 cases].
BACKGROUND
Waterproofing sprays for leather clothing have seldom been involved in severe accidents. In some circumstances, their pulmonary toxicity is marked, as shown by two case reports and a review of the literature.


METHODS
Acute alveolitis is described in two young adults without previous respiratory illness, following the use of a waterproofing spray for leather clothing. Clinical features typical of a flu-like reaction (malaise, fever and chills) were associated with dyspnea and with hemoptysis in one patient. X-ray examination evidenced lesional edema which quickly resolved after symptomatic treatment. The toxic mechanism is debated, but experimental data and clinical findings suggest the causative role of recently introduced fluoropolymers.


CONCLUSIONS
Waterproofing sprays for leather clothing may induce severe respiratory illness after massive inhalation in confined area. Treatment is supportive.
Centre antipoisons, Hôpital Edouard-Herriot, Lyon, France.
F
F
Testud
L
L
Gabrielle
M L
ML
Paquin
J
J
Descotes
D000208:Acute Disease; D000328:Adult; D000336:Aerosols / Q000633:toxicity*; D003020:Clothing; D005260:Female; D005465:Fluorocarbon Polymers / Q000633:toxicity*; D005500:Follow-Up Studies; D006801:Humans; D008171:Lung Diseases / Q000139:chemically induced*; D008297:Male; D011650:Pulmonary Alveoli / Q000187:drug effects*; D013997:Time Factors
D000336:Aerosols; D005465:Fluorocarbon Polymers
Alvéolite aiguë après utilisation d'un aérosol imperméabilisant: à propos de deux observations.