Lymphocytic interstitial pneumonitis preceding polyarticular juvenile rheumatoid arthritis.
We describe the case of a 12-year-old girl who developed lymphocytic interstitial pneumonitis at 2 years of age which preceded polyarticular rheumatoid factor (RF) positive juvenile arthritis. Her disease had a chronic active course, but showed a good response to combination therapy. The pathogenesis of these two immune processes and of the lung involvement in juvenile arthritis is discussed.
Department of Pediatrics, Sapir Medical Center, Kfar Saba, Israel.
Y
Y
Uziel
B
B
Hen
M
M
Cordoba
B
B
Wolach
D000893:Anti-Inflammatory Agents; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001171:Arthritis, Juvenile / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D001706:Biopsy; D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008218:Lymphocytosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008727:Methotrexate / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
D000893:Anti-Inflammatory Agents; D018501:Antirheumatic Agents; D006886:Hydroxychloroquine; D011241:Prednisone; D008727:Methotrexate