Role of cardiac troponin I in the evaluation of myocardial injury.
Cardiac troponin I (cTnl) is highly specific for cardiac muscle. In this study, we compared the utility of CK and CK-MB index versus cTnl in the assessment of myocardial infarction in 155 patients being evaluated for myocardial damage. As a cardiac marker for MI, Troponin I seems to be superior to CK-MB. In the subset of patients with renal disease, cTnl has definite advantages over CK-MB. In addition, the use of cTnl has the potential to replace the measurement of lactate dehydrogenase isoenzymes.
Bhagavan
N V
NV
John A. Burns School of Medicine, Department of Pathology, Honolulu, Hawaii 96822, USA. bhagavan@jabsom.biomed.hawaii.edu
Goldstein
A P
AP
Honda
S A
SA
Uyehara
J
J
Blaisdell
J
J
Sugiyama
C
C
Murakami
L
L
Kang
L
L
Fujitani
G
G
D015415:Biomarkers / Q000097:blood; D003402:Creatine Kinase / Q000097:blood*; D006801:Humans; D007527:Isoenzymes; D007676:Kidney Failure, Chronic / Q000097:blood; D007770:L-Lactate Dehydrogenase / Q000097:blood; D017202:Myocardial Ischemia / Q000097:blood / Q000175:diagnosis*; D012372:ROC Curve; D012189:Retrospective Studies; D019210:Troponin I / Q000097:blood*
D015415:Biomarkers; D007527:Isoenzymes; D019210:Troponin I; D007770:L-Lactate Dehydrogenase; D003402:Creatine Kinase