47,XYY karyotype in acute myeloid leukemia.
A case of acute myelomonocytic leukemia (AMMoL; M4) with a 47,XYY karyotype is reported. This chromosome aneuploidy was found in both bone marrow cells and mitogen-stimulated lymphocytes. The contribution of XYY chromosomal constitution in the pathogenesis of AMMoL is controversial.
Palanduz
S
S
Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University, Turkey.
Aktan
M
M
Ozturk
S
S
Tutkan
G
G
Cefle
K
K
Pekcelen
Y
Y
D006801:Humans; D015479:Leukemia, Myelomonocytic, Acute / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D014997:XYY Karyotype