[Clinical and experimental observation of xilixin granule combined with radiotherapy in treating malignant-tumors].
Thirty six patients of pulmonary or nasopharyngeal carcinoma were treated with Xilixin granule (XLXG) combined with radiotherapy and compared their efficacy with that of 31 patients treated by Zhenqi Fuzheng granule combined with radiotherapy for control. Results showed that the symptoms of Yin Deficiency syndrome in treated group were obviously improved, the leucocyte decreased by 5.6%, while in control group it reached 25.8%, the 3 year survival rate was significantly higher in treated group (75.0%) than that in control group (51.6%). Animal experiment revealed that XLXG had the effects of tumor inhibition, it could increase white blood cells, platelets and hemoglobin of patients, especially in using large dosage. These results suggested that XLXG have some protective effect against radiotherapeutic damage in patients with malignant tumor.
Ren
H Y
HY
Hunan Provincial Hospital of Oncology, Changsha.
Xi
X P
XP
Liao
Y P
YP
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D003131:Combined Modality Therapy; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007958:Leukocyte Count; D007970:Leukopenia / Q000517:prevention & control*; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy; D008297:Male; D051379:Mice; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000188:drug therapy* / Q000401:mortality / Q000532:radiotherapy; D012510:Sarcoma 180 / Q000188:drug therapy; D015996:Survival Rate
D004365:Drugs, Chinese Herbal