[Quantitative characteristics of radiation sickness clinical manifestations in large-sized laboratory animals exposed to extra-lethal radiation doses. The endocrine system reactions in dogs and monkeys].
The dynamics of cortisol, insulin and triiodothyronine content of the blood has been studied in dogs and two monkey species exposed to electron and gamma-neutron radiations in a wide supralethal--dose range. A calculated value--index of the endocrine status--has been used for integral estimation the function of the endocrine system. A considerable disintegration of the functions of separate endocrine glands has been observed, which correlates with degree of clinical manifestations in animals and radiation dose.
State Research Center of Russia-Institute of Biophysics, Moscow.
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Korotkevich
D000818:Animals; D004285:Dogs; D004703:Endocrine System / Q000378:metabolism* / Q000503:physiopathology / Q000528:radiation effects*; D000882:Haplorhini; D006854:Hydrocortisone / Q000097:blood*; D007328:Insulin / Q000097:blood*; D011829:Radiation Dosage; D011833:Radiation Injuries, Experimental / Q000097:blood* / Q000503:physiopathology; D014284:Triiodothyronine / Q000097:blood*
D007328:Insulin; D014284:Triiodothyronine; D006854:Hydrocortisone
Kolichestvennye zakonomernosti klinicheskikh proiableniĭ luchevoĭ bolezni u krupnykh laboratornykh zhivotnykh pri vozdeĭstvii izlucheniia v sverkhletal'nykh dozakh. Reaktsiia éndokrinnoĭ sistemy sobak i obez'ian.