Liver energy metabolism of Anguilla anguilla after exposure to fenitrothion.
This paper deals with the effect of fenitrothion (0.04 mg/liter) on the energy metabolism of the European eel, Anguilla anguilla, and its recovery from intoxication. Various parameters such as glycogen, lactate, proteins, total lipids, and glucose in eel liver and blood were analyzed after 2, 8, 12, 24, 32, 48, 56, 72, and 96 h of fenitrothion exposure. Subsequently, the fish were allowed recovery periods of 8, 12, 24, 48, 72, 96, 144, and 192 h in clean water, and the same parameters were evaluated. Liver glycogen and lipid contents decreased significantly during the exposure, while blood glucose levels increased markedly. Liver and blood lactate values increased during pesticide exposure, while proteins were decreased in comparison to unexposed controls. Most of the metabolic disorders did not persist after less than a week of recovery in clean water. The observed effects of fenitrothion on fish metabolism are discussed in relation to a stress syndrome, and probable reasons for alterations are also discussed.
Faculty of Biological Sciences, University of Valencia, Dr. Moliner 50, Valencia, Burjasot, 46100, Spain.
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Sancho
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Ferrando
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Fernández
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Andreu
D000811:Anguilla / Q000502:physiology*; D000818:Animals; D004734:Energy Metabolism / Q000187:drug effects*; D005278:Fenitrothion / Q000633:toxicity*; D007306:Insecticides / Q000633:toxicity*; D050356:Lipid Metabolism; D008099:Liver / Q000187:drug effects* / Q000378:metabolism; D013997:Time Factors; D014874:Water Pollutants, Chemical / Q000633:toxicity
D007306:Insecticides; D014874:Water Pollutants, Chemical; D005278:Fenitrothion