[Detection of anti-Cryptococcus neoformans antibodies in 3 groups of human sera].
The tube agglutination (TA) technique was normalized in order to determine anti-Cryptococcus neoformans antibodies, according to Palmer et al., by employing positive and negative control sera and an antigenic suspension prepared from an autochtonous strain of Cryptococcus neoformans varneofornnans. Three groups of human sera were studied and the role of TA in detecting antibodies in the group of sera from patients with active cryptococcosis (100%) was shown. In sera from banks positiveness was only 6%, while in the group of fowl breeders, considered to be "exposed", positiveness was found to be 16%, although with low titres. A discussion is carried out about the value of this technique as a complement in the diagnosis and prognosis of cryptococcosis.
Martínez Machín
G
G
Instituto de Medicina Tropical Pedro Kouri Laboratorio de Micologia.
Alvarez Bernal
L P
LP
Fernández Andreu
C
C
Llop Hernández
A
A
D000371:Agglutination; D000908:Antibodies, Fungal / Q000097:blood*; D003455:Cryptococcus neoformans / Q000276:immunology*; D006801:Humans
D000908:Antibodies, Fungal
Detección de anticuerpos anti-Cryptococcus neoformans en 3 grupos de sueros humanos.