A superfamily of proteins that contain the cold-shock domain.
Members of a family of cold-shock proteins (CSPs) are found throughout the eubacterial domain and appear to function as RNA-chaperones. They have been implicated in various cellular processes, including adaptation to low temperatures, cellular growth, nutrient stress and stationary phase. The discovery of a domain--the cold-shock domain--that shows strikingly high homology and similar RNA-binding properties to CSPs in a growing number of eukaryotic nucleic-acid-binding proteins suggests that these proteins have an ancient origin.
Graumann
P L
PL
Biological Laboratories, Harvard University, Cambridge, MA 02138, USA. graumann@fas.harvard.edu
Marahiel
M A
MA
D001426:Bacterial Proteins / Q000737:chemistry / Q000502:physiology*; D003080:Cold Temperature; D005057:Eukaryotic Cells / Q000502:physiology; D019143:Evolution, Molecular; D015964:Gene Expression Regulation, Bacterial; D008958:Models, Molecular; D011487:Protein Conformation; D012323:RNA Processing, Post-Transcriptional; D016601:RNA-Binding Proteins / Q000737:chemistry / Q000502:physiology*; D014157:Transcription Factors / Q000737:chemistry / Q000502:physiology; D029867:Xenopus Proteins
D001426:Bacterial Proteins; D016601:RNA-Binding Proteins; D014157:Transcription Factors; D029867:Xenopus Proteins; C075593:YBX2 protein, Xenopus; C077188:cold-shock protein CspB, Bacteria