Completing the sequence of the Sulfolobus solfataricus P2 genome.
The Sulfolobus solfataricus P2 genome collaborators are poised to sequence the entire 3-Mbp genome of this crenarchaeote archaeon. About 80% of the genome has been sequenced to date, with the rest of the sequence being assembled fast. In this publication we introduce the genomic sequencing and automated analysis strategy and present intial data derived from the sequence analysis. After an overview of the general sequence features, metabolic pathway studies are explained, using sugar metabolism as an example. The paper closes with an overview of repetitive elements in S. solfataricus.
Sensen
C W
CW
National Research Council of Canada, Institute for Marine Biosciences, Halifax, NS, Canada. sensencw@niji.imb.nrc.ca
Charlebois
R L
RL
Chow
C
C
Clausen
I G
IG
Curtis
B
B
Doolittle
W F
WF
Duguet
M
M
Erauso
G
G
Gaasterland
T
T
Garrett
R A
RA
Gordon
P
P
de Jong
I H
IH
Jeffries
A C
AC
Kozera
C
C
Medina
N
N
De Moors
A
A
van der Oost
J
J
Phan
H
H
Ragan
M A
MA
Schenk
M E
ME
She
Q
Q
Singh
R K
RK
Tolstrup
N
N
D001483:Base Sequence; D050260:Carbohydrate Metabolism; D002874:Chromosome Mapping; D003001:Cloning, Molecular; D019641:DNA, Archaeal / Q000235:genetics; D019766:Genes, Archaeal; D016678:Genome; D010802:Phylogeny; D012091:Repetitive Sequences, Nucleic Acid; D017422:Sequence Analysis, DNA; D012984:Software; D016944:Sulfolobus / Q000145:classification / Q000235:genetics* / Q000378:metabolism
D019641:DNA, Archaeal