Interstrain variation in the deoxynucleotide composition of Cryptococcus neoformans: nucleotide composition of Cryptococcus neoformans.
The deoxynucleotide (dNMP) composition of ten strains of C. neoformans was analysed by 32P-labelling and two-dimensional thin-layer chromatography. This technique is very sensitive for detecting rare deoxynucleotide adducts and analogues (minor bases) in DNA. The results indicate considerable variation among strains in DNA nucleotide composition.
Albert Einstein College of Medicine, Bronx, New York, USA.
D
D
Podwall
E
E
Yador
S
S
Miller
J
J
Pena
S P
SP
Franzot
J
J
Lipetz
A
A
Casadevall
J J
JJ
Steinberg
D001345:Autoradiography; D001482:Base Composition; D001938:Brazil; D002855:Chromatography, Thin Layer / Q000379:methods; D003455:Cryptococcus neoformans / Q000235:genetics* / Q000302:isolation & purification; D004271:DNA, Fungal / Q000737:chemistry* / Q000235:genetics / Q000302:isolation & purification; D003854:Deoxyribonucleotides / Q000032:analysis*; D014644:Genetic Variation; D016919:Meningitis, Cryptococcal / Q000134:cerebrospinal fluid / Q000382:microbiology; D015203:Reproducibility of Results; D013045:Species Specificity
D004271:DNA, Fungal; D003854:Deoxyribonucleotides