Pneumonia in the compromised host including cancer patients and transplant patients.
Pneumonia remains a major cause of morbidity and mortality in the immunocompromised host. The type and timing of immunosuppression will predispose the patient to infections with certain pathogens. This article discusses the types of immunosuppression and their infectious and noninfectious implications. Key points of the most commonly involved pathogens are mentioned. Finally, an approach to diagnosis and empiric therapy is discussed.
Department of Medicine, University of Florida, Gainesville, USA.
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Collin
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Ramphal
D001424:Bacterial Infections / Q000150:complications; D016026:Bone Marrow Transplantation; D006801:Humans; D016867:Immunocompromised Host; D009181:Mycoses / Q000150:complications; D009369:Neoplasms / Q000150:complications; D009503:Neutropenia / Q000150:complications; D016377:Organ Transplantation; D010272:Parasitic Diseases / Q000150:complications; D011014:Pneumonia / Q000209:etiology* / Q000628:therapy; D013997:Time Factors; D014777:Virus Diseases / Q000150:complications