[Adoption and chronic hepatitis B carrier state].
OBJECTIVE
Because there are few adoptable children in France, parents, for the last 20 years, have turned to international adoption. Alerted by the generally poor health of these children, we paid particular attention to their health problems and especially to infection by hepatitis B virus (HBV).


METHODS
The 60 internationally-adopted children seen from June 1993 to June 1997 were included in this study. All had hemogram and serum iron dosage, and search for intestinal parasites and tuberculosis was performed in each child, as were HBs antigen and HBs antibody screening. When HBs antigen was positive, HBe antigen and antibodies, HBV DNA and hepatitis C and delta serology were also studied.


RESULTS
Six out of the 60 children were HBV chronic carriers. The six presented HBs antigen and five out of the six presented viral DNA. One child was co-infected with delta virus. Serum aminotransferase was normal in three children and increased in the three others.


CONCLUSIONS
Some internationally adopted children are exposed to chronic infection by HBV. This concerns children coming from countries known for the high frequency of the disease, but also children with long stay in Eastern European nurseries. Chronic HBV carriage puts the child, as well as the family and other children in institutions and/or schools at risk, thus necessitating preventive measures.
Service de pédiatrie, centre hospitalier général de Pau, France.
J J
JJ
Choulot
S
S
Mechain
J
J
Saint Martin
V
V
Doireau
A
A
Mensire
D000300:Adoption; D002353:Carrier State / Q000175:diagnosis / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D003906:Developing Countries; D005260:Female; D005602:France; D019694:Hepatitis B, Chronic / Q000175:diagnosis / Q000453:epidemiology*; D019698:Hepatitis C, Chronic / Q000175:diagnosis / Q000453:epidemiology; D003699:Hepatitis D / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D007223:Infant; D008297:Male; D008403:Mass Screening
Adoption et portage chronique du virus B.