[Incidence and pattern of recurrent side effects in persons with different haptoglobin phenotypes during chemotherapy of pulmonary tuberculosis].
A total of 197 patients with pulmonary tuberculosis who had different haptoglobin phenotypes (Hp) were examined. Antituberculous agents were found to cause side effects in 145 patients during chemotherapy. In 82.7% of cases, adverse reactions occurred in patients with Hp 2-2 and Hp 1-1. Relapsing adverse reactions occurred mainly as allergic skin reaction and mixed syndrome. In 89% of cases, the pattern of relapsing adverse reactions did not coincide with the initial manifestations.
A M
AM
Ubaĭdullaev
F K
FK
Tashpulatova
K S
KS
Kazakov
D000293:Adolescent; D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000009:adverse effects*; D005260:Female; D006242:Haptoglobins / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D012008:Recurrence; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
D000995:Antitubercular Agents; D006242:Haptoglobins
Chastota i kharakter retsidivov pobochnykh reaktsiĭ u lits s raznymi fenotipami gaptoglobina pri khimioterapii tuberkuleza legkikh.