Intermittent-low dose G-CSF treatment in a patient with chronic neutropenia.
Chronic neutropenia in childhood has many definable causes and thus a clear cause cannot be identified in a large group of patients. Since the committed stem cell is involved in this disorder, growth factors such as granulocyte colony-stimulating factor (G-CSF) may play an important role in the treatment of severely affected children. Because of the side effects and cost, the use of G-CSF should be restricted to a minimum dose. Here we report a child with chronic neutropenia in whom intermittent-low doses of G-CSF were successfully used over a long period.
Department of Pediatrics, Hacettepe University, Faculty of Medicine, Ankara.
S
S
Yetgin
N
N
Ozbek
D002452:Cell Count; D002675:Child, Preschool; D002908:Chronic Disease; D016179:Granulocyte Colony-Stimulating Factor / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D008297:Male; D009503:Neutropenia / Q000188:drug therapy*; D009504:Neutrophils; D011994:Recombinant Proteins
D011994:Recombinant Proteins; D016179:Granulocyte Colony-Stimulating Factor