Analysis of HLA association in susceptibility to infection with Cryptococcus neoformans var. gattii in a Papua New Guinean population.
The possible association between susceptibility to infection with Cryptococcus neoformans var. gattii and HLA phenotype was examined in a group of Papua New Guinean patients. There was no evidence for a statistically significant association between susceptibility to infection and HLA class I and HLA class II phenotypes, although analysis of data which had not been subjected to the appropriate Bonferroni correction factor suggested a trend for susceptibility linked to HLA B*5601.
The Brent Laboratory, Tissue Typing, St Mary's Hospital, Praed Street, London.
M G
MG
Van Dam
R A
RA
Seaton
A J
AJ
Hamilton
D003453:Cryptococcosis / Q000235:genetics* / Q000276:immunology*; D003455:Cryptococcus neoformans; D020022:Genetic Predisposition to Disease / Q000276:immunology* / Q000382:microbiology; D006681:HLA-D Antigens / Q000276:immunology*; D015395:Histocompatibility Antigens Class I / Q000235:genetics*; D006801:Humans; D008285:Major Histocompatibility Complex; D010219:Papua New Guinea; D010641:Phenotype
D006681:HLA-D Antigens; D015395:Histocompatibility Antigens Class I