Changes in the level of sialic acid in plasma, brain and liver of inherently scorbutic rats during vitamin C and E deficiencies.
The plasma level of sialic acid (NeuAc) in inherently scorbutic [Osteogenic Disorder Shionogi (ODS)] rats was increased by 21 days of vitamin C deficiency. The brain content of NeuAc was decreased by deficiencies of these vitamins. The NeuAc level in the liver was not affected significantly by these deficiencies.
Department of Food Science and Nutrition, Nara Women's University, Japan.
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Tanaka
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Tokumaru
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Kojo
D000821:Animal Feed; D000818:Animals; D001206:Ascorbic Acid Deficiency / Q000378:metabolism*; D001921:Brain / Q000378:metabolism*; D002845:Chromatography; D008099:Liver / Q000378:metabolism*; D008297:Male; D019158:N-Acetylneuraminic Acid / Q000097:blood / Q000378:metabolism*; D018384:Oxidative Stress; D051381:Rats; D012614:Scurvy / Q000378:metabolism; D014811:Vitamin E Deficiency / Q000378:metabolism*
D019158:N-Acetylneuraminic Acid