The concentration of immunoglobulins A, G, and M in serum of patients with periodontal disease.
The aim of this study was to assess if there are any significant differences of immunoglobulin A, G and M concentration in serum of persons with different stages of periodontal destruction. The study comprised 30 persons (21 female and 9 male) with a mean age of 37.5 years, in whom periodontitis was diagnosed after clinical examination and x-ray analysis. After that the selection of patients was made according to the following criteria: 1. no systemic disease; 2. no basic periodontal therapy undertaken in the last three months; 3. presence of at least 20 teeth; 4. no antibiotics taken in the last three months. The control group consisted of 30 healthy persons with a mean age of 23.0 years in whom healthy periodontium was diagnosed after clinical examination and x-ray analysis, and only 1, 3 and 4 of above-mentioned criteria had to be fulfilled. The seversity of clinical gingival inflammation was determined by gingival index after Loben (5). The severity of periodontal destruction was assessed by measuring the pocket depth. The immunoglobulin A, G and M concentration in serum was determined by method of nephelometry on the day obtaining the sample. The mean values of immunoglobulin A, G and M in serum of patients with periodontitis were in normal ranges and not significantly different compared to the control group (p > 0.05). There is no relationship between the serum immunoglobulins A, G and M and severity of gingival inflammation and periodontal destruction.
Bokor-Bratić
M
M
Klinika za stomatologiju, Medicinski fakultet, Novi Sad.
D000328:Adult; D005260:Female; D006801:Humans; D007136:Immunoglobulins / Q000097:blood*; D008297:Male; D010518:Periodontitis / Q000276:immunology*
D007136:Immunoglobulins