Further analysis of the genome of porcine epidemic diarrhoea virus.
We report here the continued determination and analysis of the nucleotide sequence of both wild type (wt) and cell culture adapted (ca) porcine epidemic diarrhoea coronavirus (PEDV). These studies were undertaken with two objectives in mind: the identification of common and divergent features in the genomic sequences of wt and ca PEDV which can explain the differences in virulence of these isolates and the further exploration of the relationship of PEDV to other coronaviruses.
Institute of Virology, University of Zurich, Switzerland.
A
A
Bridgen
R
R
Kocherhans
K
K
Tobler
A
A
Carvajal
M
M
Ackermann
D000818:Animals; D018929:Cell Culture Techniques; D003001:Cloning, Molecular; D017934:Coronavirus / Q000235:genetics*; D016679:Genome, Viral; D016366:Open Reading Frames; D016133:Polymerase Chain Reaction; D013552:Swine; D014158:Transcription, Genetic