Serum uric acid levels in cardiovascular diseases.
OBJECTIVE
Comparison of the serum uric acid levels of healthy people (n=71) and patients with cardiovascular diseases (CVD) (n=62).


METHODS
The patients included had either experienced acute myocardial infarction (AMI) (n=31), atherosclerosis (AT) (n=23) or ischaemia (n=8). The mean values (x+/-SD) of serum uric acid levels of the control group, the patients with CVD as a whole, and patients with AMI, AT and ischaemia were 4.15+/-0.45 mg%, 5.6+/-2.06 mg%, 5.96+/-2.60 mg%, 5.38+/-1.22 mg% and 4.94+/-1.40 mg%, respectively. A statistically higher level of serum uric acid was found in the controls compared to the CVD patients (P < 0.05).


CONCLUSIONS
The higher serum uric acid levels found in CVD patients suggests that any protective antioxidant effect which uric acid has is overwhelmed by other negative effects on pathogenesis.
Department of Biochemistry, Faculty of Pharmacy, Gazi University, Ankara, Turkey.
M
M
Torun
S
S
Yardim
B
B
Simsek
S
S
Burgaz
D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000097:blood*; D003324:Coronary Artery Disease / Q000097:blood; D005260:Female; D006801:Humans; D008074:Lipoproteins / Q000097:blood; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood; D017202:Myocardial Ischemia / Q000097:blood; D014280:Triglycerides / Q000097:blood; D014527:Uric Acid / Q000097:blood*
D008074:Lipoproteins; D014280:Triglycerides; D014527:Uric Acid