[Do some drugs have adverse effects on cartilage?].
The potential chondrotoxicity of drugs is very difficult to appreciate because of the difficulties involved in evaluating the evolution of cartilage in human beings. This article attempts to summarize the data from the literature concerning the hypothetical chondrotoxicity of non steroidal anti-inflammatory drugs, fluoroquinolones, intra-articular injections of corticosteroids, and other drugs.
Clinique Rhumatologique et Thérapeutique, CHU Dupuytren, Limoges, France.
P
P
Bertin
P
P
Gillet
R
R
Treves
P
P
Netter
D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000890:Anti-Infective Agents / Q000009:adverse effects*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D002356:Cartilage / Q000187:drug effects* / Q000473:pathology; D002358:Cartilage, Articular / Q000187:drug effects* / Q000473:pathology; D024841:Fluoroquinolones; D006801:Humans; D010003:Osteoarthritis / Q000188:drug therapy / Q000503:physiopathology
D000305:Adrenal Cortex Hormones; D000890:Anti-Infective Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D024841:Fluoroquinolones
Existe-t-il des effets indésirables des médicaments sur le cartilage?