Multivariate analyses of DNA index, p62c-myc, and clinicopathological status of patients with ovarian cancer.
OBJECTIVE
To determine if either DNA index or p62c-myc is an independent prognostic variable in ovarian cancer.


METHODS
Multivariate and univariate analyses of the relation between DNA index, p62c-myc, FIGO stage, histological type, tumour grade, completeness of surgery, and patient survival in ovarian cancer were examined.


RESULTS
Multivariate analysis showed significant association of survival only with stage and grade. There was no relation between survival and DNA index.


CONCLUSIONS
DNA index is not an independent prognostic variable in ovarian cancer.
Clinical Oncology Unit, Medical School, Cambridge, UK.
M
M
Curling
S
S
Stenning
C N
CN
Hudson
J V
JV
Watson
D000704:Analysis of Variance; D014408:Biomarkers, Tumor / Q000032:analysis*; D018269:Carcinoma, Endometrioid / Q000235:genetics / Q000401:mortality / Q000473:pathology; D018291:Cystadenoma, Mucinous / Q000235:genetics / Q000401:mortality / Q000473:pathology; D018292:Cystadenoma, Papillary / Q000235:genetics / Q000401:mortality / Q000473:pathology; D018293:Cystadenoma, Serous / Q000235:genetics / Q000401:mortality / Q000473:pathology; D004273:DNA, Neoplasm / Q000032:analysis*; D003625:Data Collection; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D015999:Multivariate Analysis; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000235:genetics* / Q000401:mortality / Q000473:pathology; D011379:Prognosis; D016271:Proto-Oncogene Proteins c-myc / Q000032:analysis*; D015996:Survival Rate
D014408:Biomarkers, Tumor; D004273:DNA, Neoplasm; D016271:Proto-Oncogene Proteins c-myc