[The role of protein C in the pathogenesis of stroke].
This paper presents the role of inhibitory protein C in the haemostatic processes, types of its deficiency and current opinions concerning the role of protein C deficiency in the pathogenesis of stroke. Deficiency of protein C (PC) or activated protein C resistance (both hereditary and acquired) play a role in pathogenesis of stroke, but not so great as it was thought until quite lately. Isolated protein C deficiency in old patients does not increase the risk of stroke. But in children hereditary deficiency of PC or activated PC resistance are of great importance in pathogenesis of ischaemic or venous stroke. In the presence of additional risk factors both in children and in adults deficiency of PC may be an important condition leading to stroke occurrence.
Katedry i Kliniki Neurologii A.M., Lublinie.
J
J
Wojczal
H
H
Bartosik-Psujek
M
M
Dziduch
D000328:Adult; D001921:Brain / Q000098:blood supply; D002545:Brain Ischemia / Q000150:complications*; D006801:Humans; D020151:Protein C Deficiency / Q000150:complications*
Rola białka C w patogenezie udaru mózgu.