[Intracranial hypertension in the infant: from its physiopathology to its therapeutic management].
The pathophysiology of elevated intracranial pressure (ICP) is assessed from a three cerebral compartment model and from brain compliance. The mechanisms leading to elevated ICP (expanding process, cerebral edema, brain swelling, hydrocephalus) and their consequences (brain herniation, ischemia-anoxia phenomenon, Cushing reaction and neurogenic pulmonary edema) are overviewed. The causes of elevated ICP in children are reported with emphasis on traumatology. Diagnostic procedures include clinical assessment, fundoscopy, cerebral computerized tomography scan and specific problems of cerebrospinal fluid investigation. Methods and results of intracranial pressure monitoring are reported. The treatment of elevated ICP is based upon clinical follow-up and monitoring of ICP. General therapeutic rules consist of adequate position, suppression of any neck, skull and abdominal compression, stimuli limitation and fluid restriction. Specific treatments include mechanical ventilation, sedation and analgesia, barbiturates, anticonvulsant drugs, mannitol, corticosteroids, hypothermia, enteral nutrition, and antibiotics.
Service de pédiatrie, hôpital Jean-Bernard, CHU, Poitiers, France.
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Oriot
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Nassimi
D000698:Analgesia; D001929:Brain Edema / Q000150:complications; D015170:Cerebrospinal Fluid Pressure / Q000502:physiology; D002560:Cerebrovascular Circulation; D002648:Child; D006801:Humans; D019586:Intracranial Hypertension / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D007427:Intracranial Pressure; D012121:Respiration, Artificial
Hypertension intracrânienne de l'enfant: de la physiopathologie à la prise en charge thérapeutique.