Modeling measles, mumps, and rubella: implications for the design of vaccination programs.
Mathematical models of disease transmission are being used increasingly in the design of population-based vaccination programs. Their use is illustrated in a review of some modeling studies that have implications for the use of measles, mumps, and rubella vaccine. Investigations of vaccination strategy options yield predictions for effectiveness and cost-effectiveness analyses. A quantitative understanding of the factors affecting disease transmission enables the setting of targets for vaccination programs and underpins disease elimination initiatives.
Gay
N J
NJ
Immunisation Division, Public Health Laboratory Service Communicable Disease Surveillance Centre, London, UK. ngay@phls.co.uk
D002353:Carrier State; D015988:Cohort Effect; D004198:Disease Susceptibility / Q000276:immunology; D005260:Female; D014943:Global Health; D006801:Humans; D017589:Immunization Programs / Q000379:methods*; D007115:Immunization Schedule; D008457:Measles / Q000517:prevention & control* / Q000635:transmission; D008954:Models, Biological; D009107:Mumps / Q000517:prevention & control* / Q000635:transmission; D011247:Pregnancy; D012409:Rubella / Q000517:prevention & control* / Q000635:transmission