Pemphigus vulgaris associated with transient acanthosis nigricans like lesion.
A patient with pemphigus vulgaris was treated with predonisolone and cyclosporin. At the sites of healing erosions, hyperkeratotic, hyperpigmented plaques developed; they were clinically and histologically similar to acanthosis nigricans. These lesions regressed after a few months. This case and others described in the literature suggest that such dermatoses might be caused by immunologically as well as mechanically mediated epidermal injury.
Usui
K
K
Department of Dermatology, Jichi Medical School, Tochigi-ken, Japan.
Kondo
A
A
Nakagawa
H
H
D000052:Acanthosis Nigricans / Q000209:etiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010392:Pemphigus / Q000150:complications* / Q000188:drug therapy / Q000473:pathology