Relapsing cutaneous polyarteritis nodosa associated with streptococcal infections.
BACKGROUND
Polyarteritis nodosa is an aggressive, often fatal form of vasculitis associated with multi-organ involvement. Cutaneous polyarteritis nodosa is purported to be a more benign form of this disorder with involvement limited to the skin.


METHODS
The identification of a female patient from childhood to adulthood documenting repeated episodes of cutaneous polyarteritis nodosa following bouts of recurrent streptococcal pharyngitis.


RESULTS
Repeated bouts of streptococcal pharyngitis at ages 11, 28, and 33 years were followed by episodes of cutaneous polyarteritis nodosa, documented by histopathologic skin changes and clinical presentation, and confirmed by therapeutic management.


CONCLUSIONS
Various infectious and non-infectious conditions have been linked both to the initiation and relapse of this disease. We describe a patient with recurrent episodes of cutaneous polyarteritis nodosa spanning a period of over 20 years with each episode appearing to be linked to a prior streptococcal infection.
Department of Internal Medicine, Mercy Catholic Medical Center, Darby, Pennsylvania, USA.
M A
MA
Albornoz
A V
AV
Benedetto
M
M
Korman
S
S
McFall
C D
CD
Tourtellotte
A R
AR
Myers
D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D010612:Pharyngitis / Q000150:complications; D010488:Polyarteritis Nodosa / Q000209:etiology / Q000382:microbiology / Q000473:pathology*; D012008:Recurrence; D012867:Skin / Q000473:pathology*; D013290:Streptococcal Infections / Q000150:complications* / Q000382:microbiology