[Hypoglycemic activity of Bouvardia terniflora, Brickellia veronicaefolia, and Parmentiera edulis].
OBJECTIVE
To evaluate the hypoglycemic activity of the hexane, chloroform and methanol extracts of Bouvardia terniflora, Brickelia veronicaefolia and Parmentiera edulis.


METHODS
Normal and alloxan-induced diabetic mice were administered these plant extracts (intraperitoneal 100, 200 and 300 mg/kg).


RESULTS
The administration of 300 mg/kg of chloroform extracts from P. edulis and B. terniflora and hexane from B. veronicaefolia to diabetic mice decreased the blood glucose levels in 43.75, 58.56 and 72.13%, respectively. These extracts administered to normal mice reduced blood glucose levels in 29.61, 33.42 and 39.84%, respectively.


CONCLUSIONS
The hypoglycemic effect of these plant extracts used in traditional medicine for diabetes treatment is confirmed.
Laboratorio de Investigación de Productos Naturales, Escuela Superior de Ingeniería Química e Industrias Extractivas, Instituto Politécnico Nacional, México, D.F., México.
R M
RM
Pérez-Gutiérrez
C
C
Pérez-González
M A
MA
Zavala-Sánchez
S
S
Pérez-Gutiérrez
D000496:Alloxan; D000818:Animals; D003921:Diabetes Mellitus, Experimental / Q000139:chemically induced / Q000188:drug therapy*; D004353:Drug Evaluation, Preclinical; D005260:Female; D007004:Hypoglycemic Agents / Q000494:pharmacology*; D008297:Male; D051379:Mice; D010936:Plant Extracts / Q000494:pharmacology
D007004:Hypoglycemic Agents; D010936:Plant Extracts; D000496:Alloxan
Actividad hipoglucemiante de Bouvardia terniflora, Brickellia veronicaefolia y Parmentiera edulis.