[Clinical study on effect of xinjikang capsule in reversing left ventricular hypertrophy].
The study was conducted on the patients suffering from left ventricular hypertrophy (LVH). Ninety four cases of LVH were randomly divided into treated group (74 cases) and control group (20 cases) treated with Xinjikang capsule (XJK) and Metoprolo respectively. The results showed that XJK has remarkable reverse effects on LVH (P < 0.01). The control group although showed some effect of improvement, in comparison with pretreatmental measurement the difference was insignificanty (P > 0.05). While in comparing the two groups, the difference of effect was very significant (P < 0.01). XJK could also alleviate and eliminate to the cause of LVH, such as improving heart function and microcirculation, decreasing blood viscosity, apolipoprotein, myocardial oxygen consumption, increasing superoxide dismutase. All these parameters measured after XJK treatment were significantly different from that before treatment. The difference of them between XJK treated group and control group was also significant (P < 0.01 or P < 0.05). It suggested XJK capsule has reversing effect on LVH.
Affiliated Hospital, Anhui College of TCM, Hefei.
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Yan
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Xiao
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Wang
D000818:Animals; D000959:Antihypertensive Agents / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000188:drug therapy*; D008297:Male; D008790:Metoprolol / Q000627:therapeutic use; D008875:Middle Aged; D051381:Rats
D000959:Antihypertensive Agents; D004365:Drugs, Chinese Herbal; D008790:Metoprolol