[The effect of gidazepam on the level of monoamines in the brain of BALB/c mice].
The authors studied the content of norepinephrine, dopamine, serotonin, and their metabolites in the hypothalamus and striatum of BALB/c mice after injection of tranquilizers phenazepam (0.05 mg/kg) and hydazepam (1 mg/kg). The drugs differed in their effect on the monoamine content in the brain structures under study, which was evidence of the difference in the mechanisms of their action.
Laboratory of Pharmacologic Genetics, Russian Academy of Medical Sciences, Moscow, Russia.
A S
AS
Lapitskaia
V S
VS
Kudrin
Iu A
IuA
Blednov
D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001569:Benzodiazepines; D015306:Biogenic Monoamines / Q000378:metabolism*; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D001923:Brain Chemistry / Q000187:drug effects; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C / Q000378:metabolism*
D014151:Anti-Anxiety Agents; D015306:Biogenic Monoamines; D001569:Benzodiazepines; C017928:phenazepam; C077010:gidazepam
Vliianie gidazepama na soderzhanie monoaminov v mozge mysheĭ linii BALB/c.