Haemoglobin Le Lamentin (alpha 20 (B1) His-->Gln) in a British family: identification by electrospray mass spectrometry.
The first identification of haemoglobin Le Lamentin (alpha 20 (B1) His-->Gln) in a British patient is described. The patient was a 69 year old asymptomatic white male being screened for diabetes, whose blood was undergoing its first ever analysis for glycated haemoglobin using a Glycomat II analyser. Identification of the haemoglobin variant was by electrospray mass spectrometry.
Queen's Hospital, Burton-on-Trent, Staffordshire, UK Clinical Chemistry Department. Burton.ClinChem@Zoo.co.uk
T M
TM
Reynolds
F
F
McMillan
A
A
Smith
A
A
Hutchinson
B
B
Green
D000368:Aged; D003920:Diabetes Mellitus / Q000097:blood; D006452:Hemoglobinometry / Q000379:methods; D006455:Hemoglobins, Abnormal / Q000032:analysis*; D006801:Humans; D008297:Male; D013058:Mass Spectrometry / Q000379:methods; D006113:United Kingdom
D006455:Hemoglobins, Abnormal; C035852:hemoglobin Le Lamentin