Site-directed mutagenesis of the quinoprotein glucose dehydrogenase of Escherichia coli; the role of His262 in PQQ binding and determination of substrate specificity.
Division of Biochemistry and Molecular Biology, School of Biological Sciences, University of Southampton, UK.
G E
GE
Cozier
R A
RA
Salleh
C
C
Anthony
D001665:Binding Sites; D003067:Coenzymes / Q000378:metabolism; D004926:Escherichia coli / Q000201:enzymology*; D005948:Glucose Dehydrogenases / Q000737:chemistry / Q000378:metabolism*; D006639:Histidine; D008958:Models, Molecular; D008968:Molecular Conformation; D016297:Mutagenesis, Site-Directed; D045542:PQQ Cofactor; D011487:Protein Conformation; D015363:Quinolones / Q000737:chemistry* / Q000378:metabolism*; D011809:Quinones / Q000737:chemistry* / Q000378:metabolism*; D011994:Recombinant Proteins / Q000737:chemistry / Q000378:metabolism; D013379:Substrate Specificity
D003067:Coenzymes; D015363:Quinolones; D011809:Quinones; D011994:Recombinant Proteins; D006639:Histidine; D045542:PQQ Cofactor; D005948:Glucose Dehydrogenases; C033955:glucose dehydrogenase (pyrroloquinoline-quinone)