[Evaluation of in vitro activity of ofloxacin against 73 strains of Chlamydia trachomatis isolated from gynecologic infections].
The in vitro activity of ofloxacin, levofloxacin, ciprofloxacin, doxycyclin, erythromycin and roxithromycin was determined against 73 recent clinical strains of Chlamydia trachomatis isolated from genital infections. The MICs 90% were: 0.4; 0.1; 1.6; 0.2; 1.6 and 0.1 mg/l respectively. 100% of strains were susceptible to ofloxacin, roxithromycin and doxycyclin. Erythromycin and ciprofloxacin had a lower in vitro activity against C. trachomatis.
Laboratoire d'Immunologie et d'Allergologie, Paris, France.
F
F
Catalan
A
A
Milovanovic
C
C
Prouteau
M
M
Soulignac
D000890:Anti-Infective Agents / Q000494:pharmacology*; D002692:Chlamydia trachomatis / Q000187:drug effects* / Q000302:isolation & purification; D005069:Evaluation Studies as Topic; D005260:Female; D005831:Genital Diseases, Female / Q000382:microbiology*; D006801:Humans; D064704:Levofloxacin; D008826:Microbial Sensitivity Tests; D015242:Ofloxacin / Q000494:pharmacology*; D013045:Species Specificity
D000890:Anti-Infective Agents; D064704:Levofloxacin; D015242:Ofloxacin
Evaluation de l'activité in vitro de l'ofloxacine vis-à-vis de 73 souches de Chlamydia trachomatis isolées d'infections gynécologiques.