Reactive Intestinal Dysfunction Syndrome (RIDS) caused by chemical exposures.
In this study, the authors describe a new "reactive syndrome," Reactive Intestinal Dysfunction Syndrome (RIDS), which has similarities to the previously described clinical syndromes Reactive Airway Dysfunction Syndrome (RADS) and Reactive Upper Airway Dysfunction Syndrome (RUDS). Given that at least 5 neuropeptides are common to both the respiratory tract and digestive tract, the authors propose that the abnormal secretion of these neuropeptides or the abnormal numbers of their receptors play a role in what is perceived clinically as RADS, RUDS, and RIDS. The relatively large surface areas of both the lungs and gut render them especially vulnerable to the environment to which they are exposed constantly.
Lieberman
A D
AD
Center for Occupational and Environmental Medicine, North Charleston, South Carolina 29420-4297, USA.
Craven
M R
MR
D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects; D003109:Colonic Diseases, Functional / Q000139:chemically induced* / Q000503:physiopathology; D005260:Female; D006801:Humans; D018836:Inflammation Mediators / Q000502:physiology; D008297:Male; D008875:Middle Aged; D018777:Multiple Chemical Sensitivity / Q000209:etiology* / Q000503:physiopathology; D009479:Neuropeptides / Q000502:physiology; D009784:Occupational Diseases / Q000139:chemically induced / Q000503:physiopathology; D012307:Risk Factors
D000395:Air Pollutants, Occupational; D018836:Inflammation Mediators; D009479:Neuropeptides