Effect of Nelumbo nucifera rhizome extract on the gastrointestinal tract of rat.
Extract of Nelumbo nucifera rhizome (RNN) was used as anti-diarrheal agent to combat the diarrhea in experimental rats. The RNN extract in graded doses (100, 200, 400 and 600 mg/kg body wt.) reduced not only the frequency of defecation, wetness of fecal dropping and PGE2 induced enteropooling but also the propulsive movements of charcoal meal significantly.
Talukder
M J
MJ
Department of Physiology, Bangladesh Agricultural University, Mymensingh.
Nessa
J
J
D000284:Administration, Oral; D000818:Animals; D000930:Antidiarrheals / Q000627:therapeutic use*; D001285:Atropine / Q000627:therapeutic use; D002400:Cathartics / Q000627:therapeutic use; D002432:Cecum / Q000187:drug effects; D003967:Diarrhea / Q000188:drug therapy*; D015232:Dinoprostone / Q000494:pharmacology; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects; D007413:Intestinal Mucosa / Q000187:drug effects; D007419:Intestinal Secretions / Q000187:drug effects; D008297:Male; D010276:Parasympatholytics / Q000627:therapeutic use; D008517:Phytotherapy; D010936:Plant Extracts / Q000008:administration & dosage / Q000627:therapeutic use*; D018517:Plant Roots / Q000627:therapeutic use*; D010946:Plants, Medicinal / Q000627:therapeutic use*; D011708:Pylorus / Q000187:drug effects; D051381:Rats; D020318:Rats, Long-Evans; D014144:Tragacanth / Q000627:therapeutic use
D000930:Antidiarrheals; D002400:Cathartics; D010276:Parasympatholytics; D010936:Plant Extracts; D001285:Atropine; D014144:Tragacanth; D015232:Dinoprostone