[Mechanisms of the calcium influx across the plasma membrane].
The Ca2+ influx is mainly mediated by voltage-dependent Ca2+ channels and store depletion-dependent Ca2+ channels. The former, which mainly acts to regulate Ca2+ influx in excitable cells, is relatively clear; However, the later, which mainly functions in nonexcitable cells, remains enigmatically complicated. Following activation of the intracellular Ca2+ store, the depletion of the store provides a signal for activating Ca2+ entry across the plasma membrane via presently unknown mechanisms. This paper reviews the rapid progress in this field.
Institute of Vascular Medicine, Third Hospital, Beijing Medical University.
H W
HW
Li
Q D
QD
Han
D000818:Animals; D001693:Biological Transport, Active; D002118:Calcium / Q000378:metabolism*; D015220:Calcium Channels / Q000378:metabolism; D002462:Cell Membrane / Q000378:metabolism
D015220:Calcium Channels; D002118:Calcium