Presence of nuclear grooves in the cytology of malignant melanoma.
Nuclear grooves have been described as a cytologic feature in a variety of extrathyroid lesions. When a cytologic specimen demonstrates prominent longitudinal nuclear grooving, a wide range of pathologic lesions should be considered. To our knowledge, the two cases presented are the first report of longitudinal nuclear grooving described in cytologic preparations of malignant melanoma.
Outpatient Cytopathology Center, Johnson City, Tennessee 37601, USA. outpatientcyto@worldnet.att.net
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Rollins
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Berardo
D000368:Aged; D001707:Biopsy, Needle; D002467:Cell Nucleus / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000648:ultrastructure; D008207:Lymphatic Metastasis / Q000648:ultrastructure*; D008545:Melanoma / Q000648:ultrastructure*; D008875:Middle Aged