[Primary hyperparathyroidism].
Primary hyperparathyroidism was initially regarded as a rare and severe disease. In recent years, introduction of routine screening of serum calcium has contributed to a dramatic increased rate of detection of primary hyperparathyroidism in the population, and asymptomatic forms of this disease are now the rule. Surgery remains the only curative treatment. However a medical follow-up may be justified in asymptomatic patients whose serum calcium levels are only midly elevated and whose renal and bone status are close to normal. The medical follow-up is considered to be safe only with conscientious long-term monitoring. Surgery becomes mandatory if the follow-up shows worsening hypercalcemia, bone deterioration, renal impairment, calcium stone, or increased hypercalciuria.
Service de physiologie: explorations fonctionnelles et radio-isotopes, Hôpital Broussais, Paris.
M
M
Paillard
D005260:Female; D006801:Humans; D006934:Hypercalcemia; D006961:Hyperparathyroidism / Q000175:diagnosis / Q000601:surgery; D008297:Male; D009154:Mutation; D044169:Receptors, Calcium-Sensing; D011956:Receptors, Cell Surface / Q000235:genetics
D044169:Receptors, Calcium-Sensing; D011956:Receptors, Cell Surface
Hyperparathyroïdie primitive.