Juvenile pemphigus foliaceus.
A 7-year-old girl with generalized erythematous, scaling plaques and vesiculobullous lesions on the extremities was diagnosed as having pemphigus foliaceus. Lesional direct immunofluorescence revealed intercellular IgG, IgA and C3 deposition. The patient's serum gave positive reactions against one epitope of desmoglein 3 and the epitope of desmoglein 1 in enzyme-linked immunosorbent assays, but the blood sample for indirect immunofluorescence did not display any circulating antibodies. The patient was successfully treated systemically with prednisolone and dapsone. Currently, she is taking dapsone, 12.5 mg daily. She has been free of lesions for the last 3 years.
Mehravaran
M
M
Department of Dermatology, Albert Szent-Györgyi Medical University, H-6701 Szeged, Korányi fasor 6, PO Box 480, Szeged, Hungary. ME@derma.szote.u-szeged.hu
Morvay
M
M
Molnár
K
K
Oláh
J
J
Korom
I
I
Husz
S
S
Dobozy
A
A
D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001327:Autoimmune Diseases / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D002648:Child; D003622:Dapsone / Q000627:therapeutic use; D005260:Female; D019085:Fluorescent Antibody Technique, Direct; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D010392:Pemphigus / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D011239:Prednisolone / Q000627:therapeutic use
D000894:Anti-Inflammatory Agents, Non-Steroidal; D005938:Glucocorticoids; D003622:Dapsone; D011239:Prednisolone