[Use of an indirect immunofluorescence probe for early detection of latent malaria].
We followed up the values of the titres of malaria antibodies by the indirect immunofluorescence (IFI) technique in 52 patients: 27 Cubans and 25 foreigners with malaria. All the subjects had previously been in endemic zones. The diagnosis of the disease was based upon the thick drop test. The prevailing species was Plasmodium falciparum. The IFI technique was used at the beginning of the treatment, weekly and after 3 months. Four patients had recurrences in the 3 first weeks of the follow-up, with increased levels of the antibody titres before parasitaemia appeared. Those titres decreased with the specific treatment. We propose that the patients with increasing antibody titres in spite of the negative results of the thick drop test be considered as having a risk of developing malaria.
Instituto de Medicina Tropical Pedro Kouri.
E
E
Peláez Castro
C
C
Saladrigas Socarrás
A
A
Ruiz Pérez
J
J
Pérez Avila
D000818:Animals; D000913:Antibodies, Protozoan / Q000032:analysis; D019353:Endemic Diseases; D019084:Fluorescent Antibody Technique, Indirect; D006801:Humans; D008288:Malaria / Q000175:diagnosis*; D016778:Malaria, Falciparum / Q000175:diagnosis; D010963:Plasmodium falciparum / Q000276:immunology
D000913:Antibodies, Protozoan
Utilidad de la prueba de inmunofluorescencia indirecta en la detección precoz de recidivas palúdicas.