Two cases of endometrial adenocarcinoma arising from atypical polypoid adenomyoma.
Atypical polypoid adenomyoma (APA) most frequently presents as an endometrial polyp in premenopausal women and is believed to follow a benign course. In hysterectomy specimens from postmenopausal Japanease women, the endometrium contained an APA with an area of endometrial adenocarcinoma. A convincing transition zone between the APA and the adenocarcinoma was seen in our cases, suggesting that APA may develop into endometrial adenocarcinoma in postmenopausal women.
Sugiyama
T
T
Department of Obstetrics and Gynecology, Kurume University School of Medicine, 67 Asahi-machi, Kurume City, 830-0011, Japan.
Ohta
S
S
Nishida
T
T
Okura
N
N
Tanabe
K
K
Yakushiji
M
M
D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology*; D018194:Adenomyoma / Q000150:complications / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged