New diketopiperazines from the sponge Dysidea chlorea.
Twelve new polychlorinated diketopiperazines (7-18), along with six known ones (1-6) and a known sterol (19), were isolated from the sponge Dysidea chlorea, collected from Yap, Federated States of Micronesia. The structures of dysamides I-T (7-18) were elucidated by spectroscopic methods, and one (8) was confirmed by chemical conversion. The stereochemistry of the dysamides is discussed.
Fu
X
X
Department of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma 73019, Zealand, USA.
Ferreira
M L
ML
Schmitz
F J
FJ
Kelly-Borges
M
M
D000818:Animals; D015394:Molecular Structure; D010879:Piperazines / Q000737:chemistry / Q000302:isolation & purification*; D011161:Porifera / Q000737:chemistry*
D010879:Piperazines