[Human rotavirus infection in perinatal transmission].
OBJECTIVE
To investigate the perinatal infection of human rotavirus (HRV) in pregnant women and the effect on their neonates.


METHODS
HRV was examined by RT-PCR in cervical secretion and feces of 250 pregnant women and fecal samples of their neonates on the third postpartum day.


RESULTS
In pregnant women the HRV prevalence was 26.0% in feces and 8.8% in cervical secration, respectively. The infection rate of the 250 neonates in the first three days after birth was 4.4%, 15.6% and 22.0%, respectively. The HRV infection rate in neonates of infected mothers was 52.31%.


CONCLUSIONS
The infected mothers may be an important source for HRV infection of neonates. HRV transmitted via the labor tract and intrahospital transmission were the main sources for the neonatal infection.
Nanfang Hospital, First Military Medical University, Guangzhou.
M
M
Zhong
P
P
Yan
M
M
Xie
D005260:Female; D006801:Humans; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious; D012400:Rotavirus Infections / Q000635:transmission*