[Iatrogenic extravasations of cytotoxic or hyperosmolar aqueous solutions. Value of surgical emergency by aspiration and lavage].
Iatrogenic extravasations are characterized by their unpredictable course, the possible repercussions of functional, cosmetic and psychological sequelae, and the absence of a therapeutic consensus. The authors present the protocol used in Hôpital Saint-Louis, based on a synthesis of current procedures, consisting of emergency conservative surgical aspiration and lavage, performed in a context of close collaboration with oncolosits, intensive care physicians and radiologists. From 1994 to March 1997, fifteen patients were operated following extravasation during seven chemotherapeutic protocols, three radiographic examinations with injection of contrast agents and five resuscitation procedures. This simple protocol, applied systematically, achieved cure without cutaneous or functional sequelae in all patients. Aspiration-lavage during the first twelve hours therefore constitutes the treatment of choice of iatrogenic extravasation with cytotoxic or hyperosmolar aqueous solutions.
Service de Chirurgie Plastique, Hôpital Saint-Louis, Paris, France.
F
F
Lambert
B
B
Couturaud
E
E
Arnaud
F
F
Champeau
M
M
Revol
J M
JM
Servant
D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects*; D004638:Emergency Treatment; D005119:Extravasation of Diagnostic and Therapeutic Materials; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009994:Osmolar Concentration; D012189:Retrospective Studies; D012996:Solutions; D013396:Suction; D013514:Surgical Procedures, Operative / Q000379:methods*; D007507:Therapeutic Irrigation
D000903:Antibiotics, Antineoplastic; D012996:Solutions
Extravasations iatrogènes de solutés cytotoxiques ou hyperosmolaires. Intérêt du traitement chirurgical en urgence par aspiration et lavage.