Xanthogranulomatous cystitis associated with malignant neoplasms of the bladder.
OBJECTIVE
Two cases of xanthogranulomatous cystitis in conjunction with malignant neoplasms of the bladder are described.


RESULTS
A partial cystectomy [corrected] specimen from a 55-year-old man showed a urachal adenocarcinoma partly surrounded by a large xanthogranulomatous inflammatory mass. Multiple resections of the locally recurring tumour over the subsequent 10 years did not show further xanthogranulomatous changes. In the second case, a 76-year-old woman, a focus of xanthogranulomatous cystitis was present near a moderately differentiated transitional-cell carcinoma of the vesico-ureteric junction.


CONCLUSIONS
Xanthogranulomatous inflammation is associated with malignant neoplasms in the bladder as it is in the kidney and extra-urinary sites, as well as with benign neoplasms and non-neoplastic conditions such as urachal diverticula. The presence of a concomitant neoplasm should therefore be considered when the diagnosis of xanthogranulomatous cystitis is made.
Department of Morbid Anatomy, St Bartholomew's, Queen Mary and Westfield College, London, UK.
A W
AW
Bates
A W
AW
Fegan
S I
SI
Baithun
D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology; D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000150:complications / Q000473:pathology; D003556:Cystitis / Q000150:complications / Q000473:pathology*; D005260:Female; D006099:Granuloma / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000150:complications / Q000473:pathology*; D014973:Xanthomatosis / Q000150:complications / Q000473:pathology*