Nephron-sparing surgery for renal cell carcinoma.
In summary, NSS is the indicated treatment for patients with localized RCC and an intercurrent urological or medical condition that poses a threat to overall renal function. Recent studies have clarified the role of NSS in patients with localized unilateral RCC and a normal contralateral kidney. Recent results indicate that radical nephrectomy and NSS provide equally effective curative treatment for patients who present with a single, small (< 4 cm), and clearly localized RCC. The long-term renal functional advantage of NSS with a normal opposite kidney requires further study.
Department of Urology, Cleveland Clinic Foundation, Ohio, USA.
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Novick
D002292:Carcinoma, Renal Cell / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications / Q000503:physiopathology / Q000601:surgery*; D009392:Nephrectomy / Q000379:methods*; D009399:Nephrons