Cytosines adjacent to methylated CpG sites can be partially resistant to conversion in genomic bisulfite sequencing leading to methylation artifacts.
Harrison
J
J
Kanematsu Laboratories, Royal Prince Alfred Hospital, Missenden Road, Camperdown, New South Wales, 2050, Australia.
Stirzaker
C
C
Clark
S J
SJ
D044503:5-Methylcytosine; D016477:Artifacts; D018899:CpG Islands; D003596:Cytosine / Q000031:analogs & derivatives / Q000378:metabolism*; D019175:DNA Methylation; D017422:Sequence Analysis, DNA; D013447:Sulfites / Q000737:chemistry
D013447:Sulfites; D044503:5-Methylcytosine; D003596:Cytosine