Severe hyponatremia, neuroleptic malignant syndrome, rhabdomyolysis and acute renal failure: a case report.
Acute renal failure secondary to myoglobinuria is a rare yet possible complication of malignant neuroleptic syndrome associated with the use of dopamine antagonists. We describe the case of a 42-year-old schizophrenic man who presented with severe hyponatremia, and proceeded to acute malignant neuroleptic syndrome, rhabdomyolysis, and acute renal failure. We contend that the acute hyponatremia may have served as a precipitating factor.
Elizalde-Sciavolino
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C
Department of Medicine, Staten Island University Hospital, NY, USA.
Racco
A
A
Proscia-Lieto
T
T
Kleiner
M
M
D058186:Acute Kidney Injury / Q000150:complications*; D000328:Adult; D014150:Antipsychotic Agents / Q000009:adverse effects*; D006801:Humans; D007010:Hyponatremia / Q000150:complications*; D007177:Inappropriate ADH Syndrome / Q000150:complications*; D008297:Male; D009212:Myoglobinuria / Q000150:complications*; D009459:Neuroleptic Malignant Syndrome / Q000150:complications*
D014150:Antipsychotic Agents