Acetylator phenotypes: allele frequency in northwestern Argentina and review of acetylator distribution in the Americas.
We determined acetylator phenotypes by means of a sulfadimidine test and found that 39% of the native population of the province of Jujuy, in northwestern Argentina, have slow acetylators. The frequency of the allele controlling slow acetylation was estimated at q = 0.65 +/- 0.001. This estimate differs from those previously recorded in native and Mestizo American populations. A review of the literature on acetylator phenotypes in the Americas revealed that it is not possible to discern any clear pattern of distribution in relation to the geographic variability observed.
Instituto de Biología de la Altura, Universidad Nacional de Jujuy, San Salvador de Jujuy, Argentina.
J E
JE
Dipierri
E
E
Alfaro
I F
IF
Bejarano
A A
AA
Etchart
D000123:Acetyltransferases / Q000235:genetics*; D000293:Adolescent; D000328:Adult; D000569:Americas; D001118:Argentina; D005260:Female; D005787:Gene Frequency; D006801:Humans; D007199:Indians, South American / Q000235:genetics*; D008297:Male; D010641:Phenotype
D000123:Acetyltransferases