[Benign intracranial hypertension and chronic hypervitaminosis A].
We report a case of benign intracranial hypertension due to chronic A-hypervitaminosis and a review of literature with 30 cases in adults and adolescents. The most prominent clinical features are: predominance of young women with normal weight and cured for acne; benign intracranial hypertension without other symptoms in half of cases; wide difference of daily doses and time of continuous intake. Prognosis for vitamin A intoxication is good, when intake of vitamin is discontinued. We reviewed five cases of benign intracranial hypertension due to retinoic acid. The mechanism of vitamin A neurotoxicity is still unknown.
Service de Neurologie, H.I.A Desgenettes, Lyon.
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Drouet
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D000293:Adolescent; D000328:Adult; D001921:Brain / Q000473:pathology; D005260:Female; D006801:Humans; D006986:Hypervitaminosis A / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D011559:Pseudotumor Cerebri / Q000175:diagnosis* / Q000209:etiology* / Q000503:physiopathology
Hypertension intracrânienne bénigne et hypervitaminose A chronique.