Child and adolescent mood disorders--experience with serotonin-based therapies.
By most measures, child and adolescent depression is much like and continuous with adult depression. Aggregating all available data, much of which is relatively new, it seems most likely that noradrenergic and mixed serotonergic/noradrenergic tricyclic antidepressants are ineffective in child and adolescent depression, whereas serotonergic antidepressants (e.g., selective serotonin reuptake inhibitors) are probably effective).
Ryan
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ND
Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA.
Varma
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D
D000293:Adolescent; D000328:Adult; D002648:Child; D002997:Clomipramine / Q000627:therapeutic use; D003866:Depressive Disorder / Q000188:drug therapy*; D006801:Humans; D012701:Serotonin / Q000502:physiology; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*
D002997:Clomipramine; D012701:Serotonin; D017367:Selective Serotonin Reuptake Inhibitors