[Superficial cancer of the stomach: evolution of their characteristics over a 20 year period in one population].
OBJECTIVE
The aim of this study was to analyse the incidence, treatment and prognosis of early gastric cancer in a population-based series and to draw a picture of time trends.


METHODS
Over a 20-year period (1976-1995), 80 early gastric cancers were diagnosed in the Côte-d'Or area (493,000 residents). Incidence rates were calculated by sex, age groups and 5-year periods. Prognostic factors were determined using the Kaplan-Meier method and the Cox model.


RESULTS
Age-standardized incidence rates were 0.8/100,000 in men and 0.3/100,000 in women. Incidence increased slightly over time (NS) and their proportion among gastric cancers increased from 3.4% (1976-1980) to 7.9% (1991-1995) (P < 0.01). Among these cancers, 25 were intramucosal (31.3%), 55 were submucosal (68.8%) and 8 had lymph node metastases (10.0%). Overall 21 patients (24.1%) had already been treated for a peptic ulcer. The 5-year crude survival rate was 63.1% and the corresponding net survival rate was 86.3%. Lymph node metastases, location, sex and cancer extension and age were independent prognostic factors.


CONCLUSIONS
Though it is on the increase, the proportion of early gastric cancers remains low among gastric cancers. This study confirms the importance of performing a gastroscopy with biopsy upon each bout of ulcer and that the prognosis is lower than suggested by hospital based series.
Benhamiche
A M
AM
Registre des Cancers Digestifs (Registre associé INSERM-DGS CRI 95 05).
Faivre
J
J
Tazi
M A
MA
Darsouni
R
R
Villing
A L
AL
Couillault
C
C
D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D011230:Precancerous Conditions / Q000473:pathology; D011379:Prognosis; D013274:Stomach Neoplasms / Q000453:epidemiology / Q000473:pathology* / Q000628:therapy
Les cancers superficiels de l'estomac: évolution de leurs caractéristiques sur une période de 20 ans dans une population.