Cytosines adjacent to methylated CpG sites can be partially resistant to conversion in genomic bisulfite sequencing leading to methylation artifacts.
Kanematsu Laboratories, Royal Prince Alfred Hospital, Missenden Road, Camperdown, New South Wales, 2050, Australia.
J
J
Harrison
C
C
Stirzaker
S J
SJ
Clark
D044503:5-Methylcytosine; D016477:Artifacts; D018899:CpG Islands; D003596:Cytosine / Q000031:analogs & derivatives / Q000378:metabolism*; D019175:DNA Methylation; D017422:Sequence Analysis, DNA; D013447:Sulfites / Q000737:chemistry
D013447:Sulfites; D044503:5-Methylcytosine; D003596:Cytosine