Monte Carlo calculation of single-beam dose profiles used in a gamma knife treatment planning system.
The accuracy of single-beam dose profiles used in the algorithm of the Gamma Knife treatment planning system (Leksell GammaPlan) is verified. EGS4 Monte Carlo calculation was employed to calculate the dose distributions of single-beams in a spherical water phantom with diameter 160 mm. The beams were directed to the center of the phantom. Collimators of 4, 8, 14, and 18 mm sizes were studied. The single-beam dose profiles provided by Elekta (Manufacturer of Leksell Gamma Knife) were excellently consistent with the results of Monte Carlo for the 4, 14, and 18 mm collimators. The maximum discrepancy was less than 3% at all radial distances. For the 8 mm collimator, the maximum discrepancy was 8% in the relative dose in the radial distance range from 4.3 mm to 5.2 mm. Excellent agreement in dose profiles along x, y, and z axes for all collimator helmets by summing over all 201 sources was observed between the cases using the default single-beam dose profiles and the calculated Monte Carlo results, except for the 8 mm collimator helmet along z axis. Such difference may however be too small to give a clinical significance.
Department of Physics and Materials Science, City University of Hong Kong, Kowloon Tong, Hong Kong.
J Y
JY
Cheung
K N
KN
Yu
C P
CP
Yu
R T
RT
Ho
D000465:Algorithms; D055592:Biophysical Phenomena; D001703:Biophysics; D001932:Brain Neoplasms / Q000601:surgery; D006801:Humans; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D016634:Radiosurgery / Q000379:methods* / Q000706:statistics & numerical data; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods* / Q000706:statistics & numerical data; D013679:Technology, Radiologic