Necrotizing genital ulcerations in a premenarcheal female with mononucleosis.
BACKGROUND
Two cases of genital ulcerations caused by Epstein-Barr virus have been reported previously, one in a sexually active 23-year-old and another in a 14-year-old practicing cunnilingus.


METHODS
We report a case of Epstein-Barr virus genital ulcerations in a premenarcheal virgin. Her systemic symptoms were atypical for mononucleosis. Necrotizing genital ulcerations preceded pharyngitis and oral lesions. Cervical adenopathy, fever, and splenomegaly never developed despite serologic evidence of acute mononucleosis.


CONCLUSIONS
Genital ulcerations can be the initial manifestation of Epstein-Barr virus in adolescents who are neither sexually active nor immunocompromised.
Department of Obstetrics and Gynecology, United States Air Force Academy, Colorado Springs, Colorado, USA.
L B
LB
Hudson
S E
SE
Perlman
D000293:Adolescent; D005260:Female; D004854:Herpesvirus 4, Human; D006801:Humans; D007244:Infectious Mononucleosis / Q000150:complications*; D009336:Necrosis; D014456:Ulcer / Q000473:pathology / Q000821:virology*; D014845:Vulvar Diseases / Q000473:pathology / Q000821:virology*