In vitro susceptibilities of Chlamydia pneumoniae strains recovered from atherosclerotic coronary arteries.
Chlamydia pneumoniae strains have been recovered from arteriosclerotic coronary arteries, but their antibiotic susceptibility profiles have not yet been examined. We report in vitro susceptibility data for five cardiovascular C. pneumoniae isolates. These strains did not differ significantly from respiratory strains in their patterns of susceptibility to azithromycin, erythromycin, roxithromycin, ofloxacin, doxycycline, rifampin, and penicillin G. Roxithromycin was the most active macrolide, and rifampin was the most effective drug overall.
Institute of Medical Microbiology and Hygiene, Medical University of Lübeck, D-23538 Lübeck, Germany. gieffers@hygiene.mu-luebeck.de
J
J
Gieffers
W
W
Solbach
M
M
Maass
D016993:Chlamydophila pneumoniae / Q000187:drug effects*; D003324:Coronary Artery Disease / Q000382:microbiology*; D003331:Coronary Vessels / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests