[Enzymatic activity in cerebrospinal fluid in the monitoring of the brain lesions following intracranial tumors].
After intracranial tumour surgery edema, ischaemic and haemorrhagic changes are developing in the brain. It causes leakage of certain intracellular components and enzymes into extracellular and cerebrospinal fluid. This study includes 46 patients operated on for cerebral tumours. Lumbar CSF was obtained in postoperative course and the activity of AST, ALT, LDH, alpha HBDH, CK, gamma GT and oxygen concentration were estimated. In the control group were 10 patients suffering from sciatic pain and CSF was obtained during radiculography. For diagnostic and prognostic purposes of biochemical markers statistical analyse methods were employed and comparisons with clinical factors were carried out. In conclusions we suggest that enzymes AST, alpha HBDH, CK and oxygen content give valuable additional information of postoperative brain damage.
R
R
Zukiel
S
S
Nowak
R
R
Jankowski
J
J
Moczko
S
S
Michalak
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000201:enzymology*; D001932:Brain Neoplasms / Q000201:enzymology* / Q000601:surgery; D002555:Cerebrospinal Fluid / Q000737:chemistry / Q000201:enzymology*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D010100:Oxygen / Q000032:analysis; D011184:Postoperative Period; D012189:Retrospective Studies
D010100:Oxygen
Aktywność enzymów w płynie mózgowo-rdzeniowym po operacjach guzów wewnatrzczaszkowych.