A proposed mechanism for the induction of activator protein 1 (AP-1) binding by HIV-1 negative factor(Nef) in the macrophage cell line RAW267.4 cells.
Department of Biochemistry, University of Southampton, UK.
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Biggs
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Barton
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Mann
D000818:Animals; D016227:Benzoquinones; D017871:Calcium-Calmodulin-Dependent Protein Kinases / Q000378:metabolism; D002460:Cell Line; D004791:Enzyme Inhibitors / Q000494:pharmacology; D005419:Flavonoids / Q000494:pharmacology; D015693:Gene Products, nef / Q000235:genetics / Q000378:metabolism*; D015497:HIV-1 / Q000235:genetics / Q000378:metabolism*; D047029:Lactams, Macrocyclic; D008264:Macrophages; D019950:Mitogen-Activated Protein Kinase 1; D048052:Mitogen-Activated Protein Kinase 3; D020928:Mitogen-Activated Protein Kinases; D008954:Models, Biological; D011809:Quinones / Q000494:pharmacology; D017828:Rifabutin / Q000031:analogs & derivatives; D018808:Transcription Factor AP-1 / Q000378:metabolism*; D054311:nef Gene Products, Human Immunodeficiency Virus
D016227:Benzoquinones; D004791:Enzyme Inhibitors; D005419:Flavonoids; D015693:Gene Products, nef; D047029:Lactams, Macrocyclic; D011809:Quinones; D018808:Transcription Factor AP-1; D054311:nef Gene Products, Human Immunodeficiency Virus; D017828:Rifabutin; C020754:herbimycin; D017871:Calcium-Calmodulin-Dependent Protein Kinases; D019950:Mitogen-Activated Protein Kinase 1; D048052:Mitogen-Activated Protein Kinase 3; D020928:Mitogen-Activated Protein Kinases; C093973:2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one