Two cases of endometrial adenocarcinoma arising from atypical polypoid adenomyoma.
Atypical polypoid adenomyoma (APA) most frequently presents as an endometrial polyp in premenopausal women and is believed to follow a benign course. In hysterectomy specimens from postmenopausal Japanease women, the endometrium contained an APA with an area of endometrial adenocarcinoma. A convincing transition zone between the APA and the adenocarcinoma was seen in our cases, suggesting that APA may develop into endometrial adenocarcinoma in postmenopausal women.
Department of Obstetrics and Gynecology, Kurume University School of Medicine, 67 Asahi-machi, Kurume City, 830-0011, Japan.
T
T
Sugiyama
S
S
Ohta
T
T
Nishida
N
N
Okura
K
K
Tanabe
M
M
Yakushiji
D000230:Adenocarcinoma / Q000150:complications / Q000473:pathology*; D018194:Adenomyoma / Q000150:complications / Q000473:pathology*; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D016889:Endometrial Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged