Successful steroid treatment of idiopathic thrombocytopenic purpura after orthotopic liver transplantation for primary biliary cirrhosis.
Primary biliary cirrhosis (PBC) is an autoimmune disease of the liver frequently associated with extrahepatic autoimmune phenomena. Specific antibodies against platelet glycoproteins may play an important role in the pathogenesis of thrombocytopenia associated with PBC. This is the first report of life-threatening idiopathic thrombocytopenic purpura successfully treated with steroids in a 62-yr-old woman 2 yr after liver transplantation for PBC.
Department of Medicine, Karl-Franzens University, Graz, Austria.
P
P
Fickert
M
M
Trauner
H
H
Sill
T A
TA
Hinterleitner
R E
RE
Stauber
D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000601:surgery*; D016031:Liver Transplantation; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy* / Q000276:immunology; D011239:Prednisolone / Q000627:therapeutic use*; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000188:drug therapy* / Q000276:immunology
D005938:Glucocorticoids; D011239:Prednisolone