[Ampicillin resistance mediated by the R plasmid in strains of Shigella flexneri].
Forty Shigella flexneri strains isolated from children attended to at the Children's Hospital of Camagüey during an outbreak of acute diarrheal disease were studied; the minimal inhibitory concentration of ampicillin was determined. 33 strains (82.5%) were resistant to higher concentrations: 8 to 16 micrograms/mL, and 7 were susceptible to 4 micrograms/mL concentrations. Resistance plasmid (R) extraction was carried out in all the isolated strains and a common plasmid was found this plasmid was purified and transferred to Escherichia coli HE 101. Resistance transmission was tested.
Instituto de Medicina Tropical Pedro Kouri.
M M
MM
Ramírez
M
M
Marrero
R J
RJ
Monté
J L
JL
Maestre
L
L
Bravo
D000668:Ampicillin Resistance / Q000235:genetics*; D002648:Child; D004926:Escherichia coli / Q000235:genetics; D006801:Humans; D011815:R Factors / Q000235:genetics*; D012763:Shigella flexneri / Q000187:drug effects* / Q000235:genetics; D014169:Transformation, Bacterial / Q000235:genetics
Resistencia a la ampicilina mediada por plásmido R en cepas de Shigella flexneri.