Modeling measles, mumps, and rubella: implications for the design of vaccination programs.
Mathematical models of disease transmission are being used increasingly in the design of population-based vaccination programs. Their use is illustrated in a review of some modeling studies that have implications for the use of measles, mumps, and rubella vaccine. Investigations of vaccination strategy options yield predictions for effectiveness and cost-effectiveness analyses. A quantitative understanding of the factors affecting disease transmission enables the setting of targets for vaccination programs and underpins disease elimination initiatives.
Immunisation Division, Public Health Laboratory Service Communicable Disease Surveillance Centre, London, UK. ngay@phls.co.uk
N J
NJ
Gay
D002353:Carrier State; D015988:Cohort Effect; D004198:Disease Susceptibility / Q000276:immunology; D005260:Female; D014943:Global Health; D006801:Humans; D017589:Immunization Programs / Q000379:methods*; D007115:Immunization Schedule; D008457:Measles / Q000517:prevention & control* / Q000635:transmission; D008954:Models, Biological; D009107:Mumps / Q000517:prevention & control* / Q000635:transmission; D011247:Pregnancy; D012409:Rubella / Q000517:prevention & control* / Q000635:transmission