The areA(r) mutation of Aspergillus nidulans confers low pH sensitivity in the presence of ammonium as the only nitrogen source.
The utilization of nitrogen sources by the fungus Aspergillus nidulans is controlled by a mechanism mediated by areA, a wide domain regulatory gene. It has been verified that the strains carrying the mutant allele areAr are inhibited when growing at low pH in the presence of ammonium as the only nitrogen source. The genetic analysis of this marker showed that it apparently maps at the areA locus.
Departamento de Genetica, Faculdade de Medicina de Ribeirao Preto, Universidade de Sao Paulo, Brazil.
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Pereira
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Martinez-Rossi
D001233:Aspergillus nidulans / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism*; D002874:Chromosome Mapping; D005656:Fungal Proteins / Q000235:genetics*; D005800:Genes, Fungal; D005809:Genes, Regulator; D006863:Hydrogen-Ion Concentration; D009154:Mutation; D009584:Nitrogen / Q000378:metabolism; D000644:Quaternary Ammonium Compounds / Q000378:metabolism; D014157:Transcription Factors / Q000235:genetics*
C079728:AreA protein, Aspergillus nidulans; D005656:Fungal Proteins; D000644:Quaternary Ammonium Compounds; D014157:Transcription Factors; D009584:Nitrogen