Recurrent nodular scleritis associated with varicella zoster virus.
OBJECTIVE
To describe a case of recurrent nodular scleritis that was apparently caused by reactivation of a varicella zoster virus infection.


METHODS
Case report. Immunohistochemistry and polymerase chain reaction were used to detect viral antigen and DNA in the biopsy specimen of inflamed sclera of a patient with a history of recurrent nodular scleritis.
Uveitis and Immunology Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston 02114, USA.
C
C
Livir-Rallatos
Y
Y
El-Shabrawi
P
P
Zatirakis
P E
PE
Pellett
F R
FR
Stamey
C S
CS
Foster
D015075:2-Aminopurine / Q000031:analogs & derivatives / Q000627:therapeutic use; D000956:Antigens, Viral / Q000032:analysis; D000998:Antiviral Agents / Q000627:therapeutic use; D017931:DNA Primers / Q000737:chemistry; D004279:DNA, Viral / Q000032:analysis; D000077595:Famciclovir; D005260:Female; D019084:Fluorescent Antibody Technique, Indirect; D006563:Herpes Zoster Ophthalmicus / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D014645:Herpesvirus 3, Human / Q000235:genetics / Q000254:growth & development* / Q000276:immunology; D006801:Humans; D008875:Middle Aged; D016133:Polymerase Chain Reaction; D012008:Recurrence; D012590:Sclera / Q000473:pathology / Q000821:virology; D015423:Scleritis / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D014775:Virus Activation
D000956:Antigens, Viral; D000998:Antiviral Agents; D017931:DNA Primers; D004279:DNA, Viral; D015075:2-Aminopurine; D000077595:Famciclovir