Description of two new isolates of Streptococcus pneumoniae in spain that are highly resistant to cefotaxime.
Two strains of Streptococcus pneumoniae isolated from sputum and bronchoalveolar samples with high-level resistance to cefotaxime (MIC = 8 to 16 microg/ml) are described. One of them, belonging to serogroup 19, was also highly resistant to penicillin (MIC = 16 microg/ml), while the other, of serogroup 14, was intermediate in its resistance to penicillin (MIC = 0.25 microg/ml). To our knowledge, these are the first two strains to be isolated in Spain with such high levels of resistance to cefotaxime.
Sección de Microbiología, Hospital Universitario Virgen de la Arrixaca, El Palmar 30120, Murcia, Spain. micro@isid.es
J
J
Ruiz
M
M
Sempere
E
E
Simarro
A
A
Fenoll
D000328:Adult; D000368:Aged; D002439:Cefotaxime / Q000494:pharmacology*; D002511:Cephalosporins / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D013030:Spain; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000302:isolation & purification
D002511:Cephalosporins; D002439:Cefotaxime