[The contribution of experimental models to the physiopathology and treatment of infectious endocarditis].
The model of experimental endocarditis can be used for the investigation of the different steps in the physiopathologic process leading to the formation of the infected cardiac vegetation. It has also greatly contributed to the knowledge of the characteristics of the infected vegetation. These data allow a better understanding of the therapeutic consequences (both preventive and curative) of the physiopathologic process.
Fantin
B
B
INSERM Unité 13 Hôpital Bichat-Claude Bernard, Paris.
D000818:Animals; D019072:Antibiotic Prophylaxis; D001422:Bacterial Adhesion; D004195:Disease Models, Animal; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000503:physiopathology* / Q000517:prevention & control; D004727:Endothelium / Q000503:physiopathology; D005337:Fibrin / Q000502:physiology; D006351:Heart Valves / Q000503:physiopathology; D006801:Humans; D011817:Rabbits; D013290:Streptococcal Infections / Q000188:drug therapy / Q000503:physiopathology; D013291:Streptococcus / Q000502:physiology; D013927:Thrombosis / Q000503:physiopathology
D005337:Fibrin
Apports des modèles expérimentaux à la physiopathologie et au traitement des endocardites infectieuses.