Acute stroke following cisplatin therapy.
Cisplatin is a very effective drug in modern chemotherapy practice. It has many side effects, including neurotoxicity, and has been tentatively implicated in acute stroke. We describe a 21-year-old woman who presented with an acute stroke, confirmed on MRI as a cerebral infarction.
Gamble
G E
GE
Stroke Unit, Department of Geriatric Medicine, Hope Hospital, Salford, UK.
Tyrrell
P
P
D000208:Acute Disease; D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects*; D002544:Cerebral Infarction / Q000139:chemically induced* / Q000175:diagnosis; D002945:Cisplatin / Q000009:adverse effects*; D005260:Female; D018237:Germinoma / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D010051:Ovarian Neoplasms / Q000628:therapy
D000970:Antineoplastic Agents; D002945:Cisplatin