[Spinal metastases of malignant gliomas].
OBJECTIVE
Extracranial metastases of malignant gliomas are rare. We report 2 cases with spinal metastases in patients suffering from glioma.


METHODS
Two patients (33 and 57 years old) developed spinal canal metastases of a glioblastoma multiforme and anaplastic astrocytoma Grade III respectively 25 and 9 months after surgical resection and radiotherapy. Both metastases were confirmed pathohistologically.


RESULTS
Intraspinal metastases were irradiated with a total dose of 12.6 Gy and 50 Gy. Treatment withdrawal was necessary in one patient due to reduced clinical condition. Regression of neurological symptoms was observed in the second patient.


CONCLUSIONS
Spinal spread of malignant glioma should be considered during care and follow-up in glioma patients with spinal symptoms.
Klinik für Strahlentherapie und Nuklearmedizin, Medizinischen Universität zu Lübeck.
B
B
Materlik
U
U
Steidle-Katic
B
B
Wauschkuhn
T
T
Feyerabend
E
E
Richter
D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology*; D005260:Female; D005909:Glioblastoma / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging / Q000532:radiotherapy* / Q000556:secondary*
Spinale Metastasierung bei malignen Gliomen. Zwei Fallbeschreibungen.