[Association of Biermer's anemia and gastric carcinoid tumors].
BACKGROUND
The occurrence of gastric carcinoid tumors during the cure of pernicious anemia has been reported in the literature. Concerning a new case, we review physiopathological data of this infrequent association.


METHODS
We report the case of a 47-year-old women with pernicious anemia in which gastroscopy found two small tumors developed from enterochromaffin-like cells.


CONCLUSIONS
These tumors are usually latent and developed from enterochromaffin-like cells. The pathologic and histologic diagnosis is based on positive chromogranin A immunomarking. The physiopathological mechanism studies are in favour of the predominant part of hypergastrinemia following achlorhydria. Usually, evolution is benign and surgical or endoscopic resection recommended.
Service de médecine interne, centre hospitalier Lyon-Sud, Pierre-Bénite, France.
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Boudray
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Grange
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Durieu
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Levrat
D000752:Anemia, Pernicious / Q000150:complications* / Q000188:drug therapy; D002276:Carcinoid Tumor / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D053379:Chromogranin A; D002864:Chromogranins / Q000032:analysis; D019861:Enterochromaffin-like Cells / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D005773:Gastroscopy; D006801:Humans; D007150:Immunohistochemistry; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D013997:Time Factors; D014805:Vitamin B 12 / Q000627:therapeutic use
D053379:Chromogranin A; D002864:Chromogranins; D014805:Vitamin B 12
Association d'une anémie de Biermer et de tumeurs carcinoïdes gastriques.