[The energy parameters of the liver mitochondria under the prolonged action of halothane in vitro].
The effect of 10-, 30-, 60-, 90-, and 120-min exposure to halotane vapors on the energy parameters of mitochondria of the liver of albino rats was studied in in vitro experiments. In long-term contact of the mitochondria with halotane the respiratory and phosphorylation function of the mitochondria in oxidation of PAD- and NAD-dependent substrates was disturbed.
Ovchinnikov
I V
IV
Laboratory of Biochemistry, Uzbekistan Republic Ministry of Public Health, Tashkent.
Kim
N P
NP
Akhmerov
R N
RN
Ishankulova
G F
GF
D018685:Anesthetics, Inhalation / Q000494:pharmacology*; D000818:Animals; D004734:Energy Metabolism / Q000187:drug effects*; D006221:Halothane / Q000494:pharmacology*; D066298:In Vitro Techniques; D008930:Mitochondria, Liver / Q000187:drug effects* / Q000378:metabolism; D010085:Oxidative Phosphorylation / Q000187:drug effects; D051381:Rats; D013997:Time Factors
D018685:Anesthetics, Inhalation; D006221:Halothane
Energeticheskie parametry mitokhondriĭ pecheni pri prodolzhitel'nom deĭstvii galotana in vitro.