Re-irradiation for locally recurrent nasopharyngeal carcinoma.
Since 1989, 17 patients have undergone re-irradiation for locally recurrent nasopharyngeal cancer (NPC). The dose currently administered externally is 39.6 Gy in 36 fractions (BID) followed by an intracavitary boost (15-20 Gy). Disease persisted in five out of five patients treated palliatively. Eleven of 12 patients treated with curative intent achieved local control.
Department of Radiation Oncology, Princess Margaret Hospital/University of Toronto, Ontario, Canada.
M
M
McLean
E
E
Chow
B
B
O'Sullivan
A
A
Munro
P M
PM
Leung
D A
DA
Loblaw
T
T
Panzarella
D000328:Adult; D000368:Aged; D001918:Brachytherapy / Q000379:methods; D002277:Carcinoma / Q000532:radiotherapy*; D002423:Cause of Death; D019583:Dose Fractionation, Radiation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy*; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy*; D010166:Palliative Care; D011879:Radiotherapy Dosage; D011882:Radiotherapy, High-Energy; D015996:Survival Rate