[Pneumococcal infections in the adult population observed at the Poitiers University Hospital. Epidemiologic and clinical study].
OBJECTIVE
The aim of this study was to assess the prevalence of penicillin-nonsusceptible pneumococcus (PNSP) infections and their clinical and microbiological features among an adult population hospitalized at the Poitiers University Hospital.


METHODS
A prospective study was conducted between November 1994 and October 1995 and included all pneumococcus infections.


RESULTS
Fifty-three adults with one pneumococcal strain were included. The overall rate of PNSP strains was 28%. Infections with PNSP strains were more resistant than penicillin-susceptible pneumococcus to other antibiotics. The most frequent infection was pneumonia (36 infections, 28% PNSP).


CONCLUSIONS
The rate of PNSP in pneumococcal infections was the same in the Poitiers University Hospital as in national surveys in France. The high percentage of multiresistant strains (86.5%) limit the use of antibiotics other than beta-lactams. Surveys of pneumococcal resistance to antibiotics are needed to adapt antibiotic strategies to the local epidemiological situation.
Service des Maladies infectieuses, CHU, Poitiers.
T
T
Pasdeloup
F
F
Roblot
P
P
Aucher
J L
JL
Fauchère
B
B
Becq-Giraudon
D000328:Adult; D000367:Age Factors; D005260:Female; D005602:France / Q000453:epidemiology; D006785:Hospitals, University; D006801:Humans; D008297:Male; D011018:Pneumonia, Pneumococcal / Q000453:epidemiology* / Q000382:microbiology; D012744:Sex Ratio; D013296:Streptococcus pneumoniae / Q000302:isolation & purification; D011795:Surveys and Questionnaires
Infections à pneumocoques observées au CHU de Poitiers dans la population adulte. Etude épidémiologique et clinique.