Lymphocytic interstitial pneumonitis preceding polyarticular juvenile rheumatoid arthritis.
We describe the case of a 12-year-old girl who developed lymphocytic interstitial pneumonitis at 2 years of age which preceded polyarticular rheumatoid factor (RF) positive juvenile arthritis. Her disease had a chronic active course, but showed a good response to combination therapy. The pathogenesis of these two immune processes and of the lung involvement in juvenile arthritis is discussed.
Uziel
Y
Y
Department of Pediatrics, Sapir Medical Center, Kfar Saba, Israel.
Hen
B
B
Cordoba
M
M
Wolach
B
B
D000893:Anti-Inflammatory Agents; D018501:Antirheumatic Agents / Q000627:therapeutic use; D001171:Arthritis, Juvenile / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D001706:Biopsy; D002648:Child; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000627:therapeutic use; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D017563:Lung Diseases, Interstitial / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008218:Lymphocytosis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D008727:Methotrexate / Q000627:therapeutic use; D011241:Prednisone / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
D000893:Anti-Inflammatory Agents; D018501:Antirheumatic Agents; D006886:Hydroxychloroquine; D011241:Prednisone; D008727:Methotrexate