Budd-Chiari syndrome during nephrotic relapse in a patient with resistance to activated protein C clotting inhibitor.
It has long been known that patients with nephrotic syndrome have a hypercoagulable state, which explains the association between nephrotic syndrome, renal vein thrombosis, and thromboembolism. However, the Budd-Chiari syndrome has never been reported in nephrotic patients. This is the first report of such an association that, most likely, depended on a primary resistance to activated protein C.
Gambaro
G
G
Institute of Internal Medicine, Division of Nephrology, University of Padua, Italy. giga@ux1.unipd.it
Patrassi
G
G
Pittarello
F
F
Nardellotto
A
A
Checchetto
S
S
D'Angelo
A
A
D000328:Adult; D001777:Blood Coagulation; D006502:Budd-Chiari Syndrome / Q000150:complications* / Q000378:metabolism*; D006801:Humans; D008297:Male; D009401:Nephrosis / Q000150:complications* / Q000378:metabolism*; D011486:Protein C / Q000378:metabolism*; D012008:Recurrence
D011486:Protein C