Transient expression of calretinin in the trout habenulo-interpeduncular system during development.
Calcium-binding proteins control calcium homeostasis during neural development. The expression of one of these proteins, calretinin (CR), was monitored by immunohistochemistry in the developing habenulo-interpeduncular system of the rainbow trout, a conserved region of the brain along vertebrate phylogeny that undergoes a neurochemical reorganization in late development. No CR-immunoreactivity was observed in the habenulo-interpeduncular system during the embryonic development. CR-immunolabeling appeared in newly hatched fry and during the fry development the number of CR-immunostained elements increased progressively. During the juvenile stages (from 30 days post-hatching onwards) a gradual decrease in the number of CR-immunostained cells occurred, until its complete disappearance in adults. These variations in CR expression may represent the variable calcium-buffering needs during different developmental stages.
Departamento de Biología Celular y Patología, Universidad de Salamanca, Facultad de Medicina, Spain.
A
A
Porteros
J G
JG
Briñón
R
R
Arévalo
C
C
Crespo
J
J
Aijón
J R
JR
Alonso
D000367:Age Factors; D000818:Animals; D000831:Animals, Newborn; D064032:Calbindin 2; D004625:Embryo, Nonmammalian; D019262:Habenula / Q000196:embryology / Q000254:growth & development / Q000378:metabolism*; D007150:Immunohistochemistry; D008636:Mesencephalon / Q000196:embryology / Q000254:growth & development / Q000378:metabolism*; D017686:Oncorhynchus mykiss; D064030:S100 Calcium Binding Protein G / Q000096:biosynthesis*
D064032:Calbindin 2; D064030:S100 Calcium Binding Protein G