Vulvar intraepithelial neoplasia and carcinoma.
This report describes the classification, clinical profile, etiology, and management of high-grade squamous vulvar intraepithelial-neoplasia (VIN). Recent studies have better defined the progressive potential of high-grade VIN and the relationship of such lesions to squamous vulvar carcinoma. The histologic classification and descriptions have undergone significant refinement over the past decade. The increasing use of more conservative therapeutic approaches to high-grade VIN has demanded greater expertise in clinical evaluation to ensure invasive disease is not missed or undertreated.
Campion
M J
MJ
Gynecological Cancer Center, Royal Hospital for Women, Randwick, Sydney, Australia.
Hacker
N F
NF
D002278:Carcinoma in Situ / Q000145:classification / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000145:classification / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000601:surgery; D003127:Colposcopy; D005260:Female; D006801:Humans; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D014846:Vulvar Neoplasms / Q000145:classification / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000601:surgery