Pleuropulmonary blastoma: diagnosis by fine-needle aspiration cytology: a case report.
Pleuropulmonary blastoma (PPB) is an unusual pleural-based blastoma presenting in childhood composed by undifferentiated sarcomatous tissue with divergent differentiation and occasional benign epithelial-lined structures. We are presenting the cytologic features of PPB as diagnosed by fine-needle aspiration cytology (FNAC) of the lower lobe of the right lung in a 4-year-old girl. The smears showed highly malignant cells with hyperchromatic oval or multilobulated pleomorphic nuclei strongly suggesting an aggressive sarcoma. Histology of the aspirated material also revealed small fragments of a myxoid sarcoma with some pleomorphic anaplastic cells. Lobectomy and surgical pathologic investigation confirmed the diagnosis. PPB seems to be another tumor in which accurate diagnosis may be achieved by FNAC.
Department of Pathology, Hospital de Niños Superiora Sor María Ludovica, La Plata, Argentina. patologi@netverk.com.ar
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D001707:Biopsy, Needle; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010997:Pleural Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D018202:Pulmonary Blastoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery