[The clinical significance of disorders in the hemostatic system in infectious endocarditis].
OBJECTIVE
Study of blood clotting to evaluate hemostatic disorders in infectious endocarditis (IE).


METHODS
The trial included 124 patients with IE (61 males and 63 females aged 15-70 years). Primary and secondary IE was in 38 and 62% of patients, respectively.


RESULTS
Clinically evident hemostatic disorders were observed in 93(74.2%) cases. They manifested as intravascular platelet activation with development of hypercoagulatory status and chronic DIC-syndrome.


CONCLUSIONS
A differentiated approach is advisable to correction of thrombotic disorders in IE basing on the severity of blood coagulation impairment.
A S
AS
Mil'to
D000293:Adolescent; D000328:Adult; D000368:Aged; D001778:Blood Coagulation Disorders / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D001780:Blood Coagulation Tests; D004697:Endocarditis, Bacterial / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000097:blood / Q000150:complications / Q000175:diagnosis*; D013212:Staphylococcus epidermidis
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