Adenocarcinoma in an ileal pouch after prior proctocolectomy for carcinoma in a patient with ulcerative pancolitis.
We report the first known case of pouch carcinoma in a 35-year-old female patient following proctocolectomy for adenocarcinoma in ulcerative pancolitis with backwash ileitis. Pouch cancer was diagnosed 2 years after the pelvic pouch procedure, illustrating that there might be a risk of pouch cancer in such patients. Adenocarcinoma arising in an ileoanal reservoir is rare. Two other cases have been reported: both patients concerned were believed to have developed cancer in small areas of residual remaining rectal mucosa.
Institut für Pathologie, Klinikum Bayreuth, Germany. vieth.lkpathol@uni-bayreuth.de
M
M
Vieth
M
M
Grunewald
C
C
Niemeyer
M
M
Stolte
D000230:Adenocarcinoma / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D000293:Adolescent; D000714:Anastomosis, Surgical; D003093:Colitis, Ulcerative / Q000150:complications*; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D007079:Ileitis / Q000150:complications / Q000473:pathology; D007413:Intestinal Mucosa / Q000473:pathology; D016609:Neoplasms, Second Primary / Q000209:etiology* / Q000473:pathology; D016737:Proctocolectomy, Restorative / Q000009:adverse effects*