[Distribution of the 32 bp deletion in the CCR5 chemokine receptor gene in populations of the Volga-Ural region].
Data on the frequency of the CCR5 chemokine receptor-gene 32-bp deletion in seven Turkic (Bashkir, Tatar, and Chuvash) and Finno-Ugric (Mari, Komi, Mordvinian, and Udmurt) populations of the Volga-Ural region, obtained by means of the PCR technique, are presented. The deletion frequency varied from 2.17% in the northwestern ethnogeographic group of Bashkirs to 13.44% in the Tatar population, with a mean frequency value of 7.02% for the region. The only deletion homozygote found belonged to the Udmurt population. The results indicate that the frequency distribution of the mutant allele in Volga-Ural populations coincided with that in European populations.
Department of Biochemistry and Cytochemistry, Ufa Scientific Center, Russian Academy of Sciences, Bashkortostan, Russia. molgen@chembia.ufanet.ru
A R
AR
Galeeva
E K
EK
Khusnutdinova
P A
PA
Slominskiĭ
S A
SA
Limborskaia
D020029:Base Pairing; D005260:Female; D017353:Gene Deletion; D005787:Gene Frequency; D018740:Genetic Heterogeneity; D005838:Genotype; D006801:Humans; D008297:Male; D016133:Polymerase Chain Reaction; D019707:Receptors, Chemokine / Q000235:genetics*; D012426:Russia
D019707:Receptors, Chemokine
Rasprostranennost' deletsii 32 pn v gene retseptora khemokinov CCR5 v populiatsiiakh Volgo-Ural'skogo regiona.