[The effect of gidazepam on the level of monoamines in the brain of BALB/c mice].
The authors studied the content of norepinephrine, dopamine, serotonin, and their metabolites in the hypothalamus and striatum of BALB/c mice after injection of tranquilizers phenazepam (0.05 mg/kg) and hydazepam (1 mg/kg). The drugs differed in their effect on the monoamine content in the brain structures under study, which was evidence of the difference in the mechanisms of their action.
Lapitskaia
A S
AS
Laboratory of Pharmacologic Genetics, Russian Academy of Medical Sciences, Moscow, Russia.
Kudrin
V S
VS
Blednov
Iu A
IuA
D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001569:Benzodiazepines; D015306:Biogenic Monoamines / Q000378:metabolism*; D001921:Brain / Q000187:drug effects* / Q000378:metabolism; D001923:Brain Chemistry / Q000187:drug effects; D008297:Male; D051379:Mice; D008807:Mice, Inbred BALB C / Q000378:metabolism*
D014151:Anti-Anxiety Agents; D015306:Biogenic Monoamines; D001569:Benzodiazepines; C017928:phenazepam; C077010:gidazepam
Vliianie gidazepama na soderzhanie monoaminov v mozge mysheĭ linii BALB/c.