Genetic mapping of mouse centromere protein (Incenp and Cenpe) genes.
Inner centromere protein (INCENP) and centromere protein E (CENPE) are two functionally important proteins of the higher eukaryotic centromere. Using a mouse Incenp genomic DNA and a mouse Cenpe cDNA to analyze recombinant inbred mouse sets, as well as interspecific backcross panels, we have mapped these genes to the proximal regions of mouse Chromosomes 19 and 6, respectively. Comparison of Cenpe and human CENPE, which maps to chromosome region 4q24-->q25, has further identified a new region of homology between the two species.
The Murdoch Institute, Royal Children's Hospital, Parkville, Victoria, Australia. fowlerk@cryptic.rch.unimelb.edu.au
K J
KJ
Fowler
R
R
Saffery
B T
BT
Kile
D V
DV
Irvine
D F
DF
Hudson
H E
HE
Trowell
K H
KH
Choo
D000818:Animals; D002503:Centromere / Q000235:genetics*; D002868:Chromosomal Proteins, Non-Histone / Q000235:genetics*; D002874:Chromosome Mapping; D018076:DNA, Complementary; D006239:Haplotypes; D051379:Mice
D002868:Chromosomal Proteins, Non-Histone; D018076:DNA, Complementary; C513185:Incenp protein, mouse; C068688:centromere protein E