Gastro-intestinal complications following neonatal cardiac catheterisation.
BACKGROUND
Infants with congenital cyanotic heart disease are at increased risk of developing necrotising enterocolitis (NEC). We examined a cohort of infants with congenital cyanotic heart disease in order to assess the role of cardiac catheterisation in the pathogenesis of NEC.


METHODS
Sixty-five infants with congenital cyanotic heart disease were assessed in a retrospective study. The incidence of gastrointestinal complications was compared between infants who required cardiac catheterisation and those who did not.


RESULTS
There were 38 infants who required cardiac catheterisation and 27 who did not. Both groups were similar for known risk factors for NEC. Eleven of the catheterised infants developed bloody stools versus 4 of the non-catheterised infants (OR 2.34; 95% CI 0.65-8.36). Five of the catheterised infants developed classical NEC versus none of the non-catheterised infants (OR 4.24; 95% CI 0.47-38.5). Four of the five infants who developed NEC did so during re-introduction of feeds following cardiac catheterisation.


CONCLUSIONS
Infants with congenital cyanotic heart disease appear to be at a greater risk of gastrointestinal complications including necrotising enterocolitis in the days following cardiac catheterisation. We suggest a more cautious approach to feeding is required during this period.
Royal Maternity Hospital, Belfast, Northern Ireland. dsweet@dnet.co.uk
D G
DG
Sweet
B
B
Craig
H L
HL
Halliday
C
C
Mulholland
D006328:Cardiac Catheterization / Q000009:adverse effects*; D003490:Cyanosis / Q000150:complications / Q000151:congenital / Q000628:therapy*; D020345:Enterocolitis, Necrotizing / Q000209:etiology*; D006330:Heart Defects, Congenital / Q000150:complications / Q000628:therapy*; D006801:Humans; D007231:Infant, Newborn; D012189:Retrospective Studies; D012307:Risk Factors