[Study of the relationship dengue-pregnancy in a group of cuban-mothers].
The current worldwide situation of dengue infection, and particularly in the American continent, is analyzed taking into account the increasing risk for infection during pregnancy which exists in endemic areas; the consequences of an eventual vertical transmission of the virus are practically unknown yet. We studied 59 women who gave birth to their children between 5 and 9 months after the "peak phase" of the type 2 dengue virus epidemic which broke out in Cuba in 1981. Sera of the mothers and newborns were studied through various serologic techniques in order to detect antibodies; in some cases we tried to isolate the virus, without success, from serum samples taken from the newborns; among these, we found 4 cases with positive IgM. These newborns showed neither apparent fetal damage at birth nor further alterations in a follow-up carried out when they reached 5 years of age. The need of carrying out further studies contributing to establish an adequate management of pregnant women infected by dengue virus is discussed.
Instituto de Medicina Tropical Pedro Kouri.
R
R
Fernández
T
T
Rodríguez
F
F
Borbonet
S
S
Vázquez
M G
MG
Guzmán
G
G
Kouri
D000914:Antibodies, Viral / Q000097:blood*; D003462:Cuba / Q000453:epidemiology; D003715:Dengue / Q000453:epidemiology / Q000276:immunology*; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood*; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000276:immunology*
D000914:Antibodies, Viral; D007075:Immunoglobulin M
Estudio de la relación dengue-embarazo en un grupo de madres cubanas.