[Small retinal, cochlear, and cerebral infarctions in the young patient, "SICRET" syndrome of Susac syndrome].
A 22-year-old-lady presented with multiple occlusions of the branches of the central retinal artery, accompanied by neuro-encephalic disorders and deafness. This triad is known as SICRET Syndrome (Small Infarction of Cochlear, Retinal and Encephalic Tissue). This rare syndrome, as well referred to as Susac syndrome, affects only the women and the three tissues mentioned above: eye, ear, brain. The course was characterised by a series of partially regressive evolutive steps. A remission had been obtained since two years with immuno-supressor and anti-coagulant therapy. The neuro-encephalic and cochlear disorder regressed in contrast to the severe sequel on the right eye.
Mala
L
L
Service d'Ophtalmologie du Pr. A. Raspiller, Hôpital Central, Nancy.
Bazard
M C
MC
Berrod
J P
JP
Wahl
D
D
Raspiller
A
A
D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D001160:Arterioles / Q000473:pathology; D002544:Cerebral Infarction / Q000150:complications / Q000188:drug therapy; D003051:Cochlea / Q000098:blood supply*; D003638:Deafness / Q000209:etiology; D003937:Diagnosis, Differential; D004359:Drug Therapy, Combination; D005260:Female; D006261:Headache / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007238:Infarction / Q000150:complications / Q000188:drug therapy; D008279:Magnetic Resonance Imaging; D009925:Organ of Corti / Q000098:blood supply; D011239:Prednisolone / Q000627:therapeutic use; D015356:Retinal Artery Occlusion / Q000150:complications / Q000188:drug therapy; D020156:Salicylic Acid / Q000627:therapeutic use; D013577:Syndrome; D014717:Vertigo / Q000209:etiology; D014786:Vision Disorders / Q000209:etiology; D014859:Warfarin / Q000627:therapeutic use
D000925:Anticoagulants; D007166:Immunosuppressive Agents; D014859:Warfarin; D011239:Prednisolone; D020156:Salicylic Acid
Petits infarctus rétiniens, cochléaires et cérébraux du sujet jeune, ou "SICRET" syndrome ou syndrome de Susac.