Preliminary evaluation of a prototype spatially resolved spectrometer.
Near infrared spectroscopy (NIRS) has become an established research tool and is now being explored in several clinical settings [7]. However, until recently NIRS has not been fully quantified and changes have been difficult to interpret [4]. A new development by Hamamatsu Photonics, called the Spatially Resolved Spectrometer (SRS), proposes to be able to give a quantitative measure of oxygen saturation. We have incorporated the SRS into a multimodality monitoring system in three different clinical situations: 1) patients undergoing routine cardiopulmonary bypass, 2) head injured patients and 3) patients undergoing right-sided carotid endarterectomy. The importance of this investigation is in the development of the SRS machine which shows potential as a useful clinical tool. The results demonstrated good correlation between SRS and jugular venous oximetry (SjO2) in about 50% of patients. Although these results are encouraging, this study suggests that the SRS, in its present form, is not a reliable clinical monitor of cerebral oxygen saturation.
University Department of Neurosurgery, Addenbrooke's Hospital, Cambridge, U.K.
P G
PG
al-Rawi
P
P
Smielewski
P J
PJ
Kirkpatrick
D001921:Brain / Q000098:blood supply*; D001925:Brain Damage, Chronic / Q000175:diagnosis* / Q000503:physiopathology; D001930:Brain Injuries / Q000503:physiopathology; D002545:Brain Ischemia / Q000175:diagnosis* / Q000503:physiopathology; D002315:Cardiopulmonary Bypass; D002540:Cerebral Cortex / Q000098:blood supply; D016894:Endarterectomy, Carotid; D006801:Humans; D016343:Monitoring, Intraoperative / Q000295:instrumentation; D008991:Monitoring, Physiologic / Q000295:instrumentation; D010101:Oxygen Consumption / Q000502:physiology; D012680:Sensitivity and Specificity; D019265:Spectroscopy, Near-Infrared / Q000295:instrumentation*