[The corrective action of antibodies in experimental intestinal dysbacteriosis].
As shown in this work, antisera obtained after the immunization of animals with vaccines, prepared from Salmonella minnesota strain R595 (Re mutant) or Escherichia coli O14 having enterobacterial common antigen (ECA), as well as human antisera with elevated titers of antibodies to Re glycolipid or to LPS O14 (ECA), inhibited the development of experimental intestinal dysbacteriosis in white mice, induced by the administration of ampyox in large doses. The degree of the inhibiting action of the antisera was proportional to antibody titers, which was indicative of the fact that antibodies possibly played some role in the regulation of the amount of intestinal microflora.
Chkhaidze
I G
IG
Centre Hydrobios, Institute of Human Morphology, Moscow, Russia.
Likhoded
V G
VG
Likhoded
N V
NV
Lobova
E A
EA
Iakovlev
M Iu
MIu
D000667:Ampicillin; D000818:Animals; D000907:Antibodies, Bacterial / Q000627:therapeutic use*; D000942:Antigens, Bacterial / Q000276:immunology; D001428:Bacterial Vaccines / Q000627:therapeutic use*; D004306:Dose-Response Relationship, Immunologic; D004353:Drug Evaluation, Preclinical; D004359:Drug Therapy, Combination; D004926:Escherichia coli / Q000276:immunology*; D004927:Escherichia coli Infections / Q000139:chemically induced / Q000382:microbiology / Q000628:therapy*; D005260:Female; D006017:Glycolipids / Q000276:immunology; D006801:Humans; D007114:Immunization / Q000379:methods; D007410:Intestinal Diseases / Q000139:chemically induced / Q000382:microbiology / Q000628:therapy*; D008070:Lipopolysaccharides / Q000276:immunology; D008297:Male; D051379:Mice; D010068:Oxacillin; D011817:Rabbits; D012475:Salmonella / Q000276:immunology*; D013997:Time Factors
D000907:Antibodies, Bacterial; D000942:Antigens, Bacterial; D001428:Bacterial Vaccines; D006017:Glycolipids; D008070:Lipopolysaccharides; C055264:Re-glycolipid; D000667:Ampicillin; C000307:broadcillin; D010068:Oxacillin
Korektiruiushchee deĭstvie antitel pri éksperimental'nom kishechnom disbakterioze.