[The POEMS syndrome--a rare multiorgan disease].
POEMS syndrome is a rare multisystemic disorder characterized by a variable constellation of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes. The syndrome is believed to be immune-mediated and is probably related to the pathological monoclonal component caused by a myeloma or a plasmocytoma. The treatment is aimed at the underlying plasma cell dyscrasia. We have studied three patients with this rare syndrome. This article presents the clinical picture of each one and a survey of the literature.
Nevrologisk avdeling, Haukeland Sykehus, Bergen.
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Storstein
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Gjerde
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Vedeler
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Nesthus
D000328:Adult; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D016878:POEMS Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000276:immunology
POEMS-syndromet--en sjelden multiorgansykdom.