[Extradural temporopolar approach for giant pituitary adenomas invading the cavernous sinus and parasellar regions].
OBJECTIVE
An extradural temporopolar approach has recently been used in the treatment of the parasellar, infrachiasmatic, or intracavernous regions. In this approach, the temporal (superficial) dural layer is separated from the deep layer (inner cavernous membrane) to expose the cavernous sinus extradurally. We report our experiences with 5 cases in which a giant pituitary adenoma invading the cavernous sinus and parasellar regions was resected via the extradural temporopolar approach.


METHODS
Between January 1995 and December 1997, 60 patients with pituitary adenomas were operated on at Okayama University Hospital. The extradural temporopolar approach was used for 5 patients who had a giant pituitary adenoma invading the cavernous sinus and parasellar regions. The 5 patients were women aged from 32 to 62 years and presented with a visual dysfunction. Four patients had hormonally non-functioning pituitary adenomas and one had a growth-hormone secreting pituitary adenoma.


RESULTS
The operations resulted in 1 total, 3 subtotal and 1 partial removal. There was no operative mortality or major morbidity. Transient oculomotor palsy occurred in 2 cases postoperatively. This approach provided excellent exposure of the tumor, relevant cranial nerves and arteries in and around the cavernous sinus through extradural retraction of the temporal lobe, allowing for sufficient resection of the intracavernous and parasellar portion of the tumor. Tumors invading the inferior portion of the clivus or the contralateral cavernous sinus could not be removed through this approach.


CONCLUSIONS
Our findings suggest that the extradural temporopolar approach is useful for resection of giant pituitary adenomas invading the cavernous sinus and parasellar regions.
Department of Neurological Surgery, Okayama University Medical School, Japan.
T
T
Tamiya
Y
Y
Ono
I
I
Date
M
M
Kawauchi
K
K
Matsumoto
T
T
Ohmoto
D000236:Adenoma / Q000473:pathology / Q000601:surgery*; D000328:Adult; D002426:Cavernous Sinus / Q000473:pathology; D005260:Female; D006801:Humans; D007016:Hypophysectomy / Q000379:methods*; D008866:Microsurgery / Q000379:methods; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D010911:Pituitary Neoplasms / Q000473:pathology / Q000601:surgery*; D019292:Skull Base Neoplasms / Q000473:pathology / Q000601:surgery; D019043:Vascular Neoplasms / Q000473:pathology / Q000601:surgery