[Study of the relationship dengue-pregnancy in a group of cuban-mothers].
The current worldwide situation of dengue infection, and particularly in the American continent, is analyzed taking into account the increasing risk for infection during pregnancy which exists in endemic areas; the consequences of an eventual vertical transmission of the virus are practically unknown yet. We studied 59 women who gave birth to their children between 5 and 9 months after the "peak phase" of the type 2 dengue virus epidemic which broke out in Cuba in 1981. Sera of the mothers and newborns were studied through various serologic techniques in order to detect antibodies; in some cases we tried to isolate the virus, without success, from serum samples taken from the newborns; among these, we found 4 cases with positive IgM. These newborns showed neither apparent fetal damage at birth nor further alterations in a follow-up carried out when they reached 5 years of age. The need of carrying out further studies contributing to establish an adequate management of pregnant women infected by dengue virus is discussed.
Fernández
R
R
Instituto de Medicina Tropical Pedro Kouri.
Rodríguez
T
T
Borbonet
F
F
Vázquez
S
S
Guzmán
M G
MG
Kouri
G
G
D000914:Antibodies, Viral / Q000097:blood*; D003462:Cuba / Q000453:epidemiology; D003715:Dengue / Q000453:epidemiology / Q000276:immunology*; D005260:Female; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood*; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology / Q000276:immunology*
D000914:Antibodies, Viral; D007075:Immunoglobulin M
Estudio de la relación dengue-embarazo en un grupo de madres cubanas.