Renal lupus in pregnancy.
The outlook of pregnancy for women with lupus nephritis is usually favourable if the disease has been quiescent for at least 3 months before pregnancy, and if, at conception, serum creatinine is less than 140 mumol/l, proteinuria less than 3 grams/25 hours and blood pressure controlled. The risk of fetal loss is, however, 2-3 times higher than in the normal population and pre-eclampsia, prematurity and fetal growth retardation frequently complicate these pregnancies. Pregnancies in women with lupus nephritis are high-risk pregnancies and they require intense fetal and maternal surveillance.
Department of Internal Medicine, Peijas Hospital, Vantaa, Finland.
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Julkunen
D005260:Female; D006801:Humans; D008181:Lupus Nephritis / Q000150:complications* / Q000453:epidemiology*; D011225:Pre-Eclampsia / Q000150:complications* / Q000453:epidemiology*; D011247:Pregnancy; D011256:Pregnancy Outcome; D015995:Prevalence