Immunocytochemistry of fine-needle aspirates from central giant cell granuloma.
Fine needle aspiration biopsy (FNAB) is an important technique in the diagnosis of oral and maxillofacial conditions. We describe here the cytological and immunocytological findings in four patients with central giant cell granuloma. All the aspirates showed mononuclear cells associated with many giant cells. We conclude that immunocytochemical examination of FNAB specimens helps to confirm the provisional clinical diagnosis of central giant cell granuloma.
Castro
W H
WH
Department of Oral Surgery and Pathology, Minas Gerais Federal University, School of Dentistry, Brazil.
Filho
E C
EC
de Souza
P E
PE
Gomez
R S
RS
D000293:Adolescent; D000328:Adult; D015703:Antigens, CD / Q000032:analysis; D015214:Antigens, Differentiation, Myelomonocytic / Q000032:analysis; D001707:Biopsy, Needle; D002467:Cell Nucleus / Q000648:ultrastructure; D002648:Child; D002843:Chromatin / Q000648:ultrastructure; D003593:Cytoplasm / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005260:Female; D015726:Giant Cells / Q000473:pathology; D006101:Granuloma, Giant Cell / Q000473:pathology*; D006684:HLA-DR Antigens / Q000032:analysis; D006801:Humans; D007124:Immunoenzyme Techniques; D007150:Immunohistochemistry; D008264:Macrophages / Q000473:pathology; D008336:Mandibular Diseases / Q000473:pathology*; D008439:Maxillary Diseases / Q000473:pathology*; D000097382:CD68 Molecule
D015703:Antigens, CD; D015214:Antigens, Differentiation, Myelomonocytic; D002843:Chromatin; D006684:HLA-DR Antigens; C067980:CD68 antigen, human; D000097382:CD68 Molecule