Chlorambucil-induced pulmonary disease: a case report and review of the literature.
A 77-year-old man developed pneumonitis while on chlorambucil therapy for chronic lymphocytic leukemia, with a cumulative dose of 2700 mg. The condition improved promptly with the discontinuation of the drug and initiation of steroids. A case report and review of the literature are presented in this paper.
Medicine Branch, National Cancer Institute, Bethesda, MD 20892, USA.
H T
HT
Khong
J
J
McCarthy
D000368:Aged; D018906:Antineoplastic Agents, Alkylating / Q000009:adverse effects* / Q000627:therapeutic use; D002699:Chlorambucil / Q000009:adverse effects*; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000188:drug therapy; D008171:Lung Diseases / Q000139:chemically induced*; D008297:Male
D018906:Antineoplastic Agents, Alkylating; D002699:Chlorambucil