Transgenic animal models for mutagenesis studies: role in mutagenesis research and regulatory testing.
MacGregor
J T
JT
Center for Drug Evaluation and Research, Food and Drug Administration, Rockville, Maryland 20857, USA.
D000818:Animals; D030801:Animals, Genetically Modified / Q000235:genetics*; D002274:Carcinogens, Environmental / Q000633:toxicity; D008322:Mammals / Q000235:genetics; D016296:Mutagenesis; D009152:Mutagenicity Tests / Q000191:economics / Q000379:methods*; D009153:Mutagens / Q000633:toxicity; D012107:Research Design; D014116:Toxicology / Q000331:legislation & jurisprudence*; D019076:Transgenes / Q000187:drug effects / Q000528:radiation effects
D002274:Carcinogens, Environmental; D009153:Mutagens