Right-side neglect in Alzheimer's disease.
Unilateral neglect--the inability to pay attention to events occurring on one side of space--usually occurs for left-side events after focal right-hemisphere damage. We report a 73-year-old woman with probable AD and no evidence of focal brain lesions who showed signs of right-side neglect and extinction. Neglect was more severe after 1 year. Neuroimaging techniques demonstrated an asymmetry of cortical involvement, with cortical atrophy and hypoperfusion predominant in the left posterior regions. Unilateral neglect should be assessed systematically in AD.
INSERM Unit 324, Paris, France.
P
P
Bartolomeo
G
G
Dalla Barba
M F
MF
Boissé
A C
AC
Bachoud-Lévi
J D
JD
Degos
F
F
Boller
D000368:Aged; D000544:Alzheimer Disease / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D001288:Attention / Q000502:physiology*; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000503:physiopathology; D004292:Dominance, Cerebral / Q000502:physiology*; D005260:Female; D006801:Humans; D008609:Mental Status Schedule; D010468:Perceptual Disorders / Q000209:etiology* / Q000503:physiopathology; D011597:Psychomotor Performance; D013028:Space Perception / Q000502:physiology*; D015899:Tomography, Emission-Computed, Single-Photon