Ropivacaine-induced seizure after extradural anaesthesia.
Ropivacaine is considered safer than bupivacaine, on the basis of experimental and human data that indicate a lower systemic toxicity. Here we report the occurrence of a single seizure after i.v. administration of ropivacaine 120 mg intended for extradural block in a patient having postpartum, tubal ligation. The only prodromal symptom was nervousness, and the only cardiovascular manifestation was sinus tachycardia. Systemic toxicity, although less than that expected with bupivacaine, can occur with ropivacaine.
Department of Anesthesiology, Medical School, University of Texas Health Science Center-Houston, USA.
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Abouleish
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Elias
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Nelson
D000328:Adult; D000577:Amides / Q000009:adverse effects*; D000767:Anesthesia, Epidural / Q000009:adverse effects*; D000773:Anesthesia, Obstetrical; D000779:Anesthetics, Local / Q000009:adverse effects*; D004830:Epilepsy, Tonic-Clonic / Q000139:chemically induced*; D005260:Female; D006801:Humans; D007275:Injections, Intravenous; D008508:Medication Errors; D011247:Pregnancy; D000077212:Ropivacaine; D013246:Sterilization, Tubal
D000577:Amides; D000779:Anesthetics, Local; D000077212:Ropivacaine