Serum uric acid levels in cardiovascular diseases.
OBJECTIVE
Comparison of the serum uric acid levels of healthy people (n=71) and patients with cardiovascular diseases (CVD) (n=62).


METHODS
The patients included had either experienced acute myocardial infarction (AMI) (n=31), atherosclerosis (AT) (n=23) or ischaemia (n=8). The mean values (x+/-SD) of serum uric acid levels of the control group, the patients with CVD as a whole, and patients with AMI, AT and ischaemia were 4.15+/-0.45 mg%, 5.6+/-2.06 mg%, 5.96+/-2.60 mg%, 5.38+/-1.22 mg% and 4.94+/-1.40 mg%, respectively. A statistically higher level of serum uric acid was found in the controls compared to the CVD patients (P < 0.05).


CONCLUSIONS
The higher serum uric acid levels found in CVD patients suggests that any protective antioxidant effect which uric acid has is overwhelmed by other negative effects on pathogenesis.
Torun
M
M
Department of Biochemistry, Faculty of Pharmacy, Gazi University, Ankara, Turkey.
Yardim
S
S
Simsek
B
B
Burgaz
S
S
D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000097:blood*; D003324:Coronary Artery Disease / Q000097:blood; D005260:Female; D006801:Humans; D008074:Lipoproteins / Q000097:blood; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood; D017202:Myocardial Ischemia / Q000097:blood; D014280:Triglycerides / Q000097:blood; D014527:Uric Acid / Q000097:blood*
D008074:Lipoproteins; D014280:Triglycerides; D014527:Uric Acid