[Clinical studies of Olbas oil tolerance and its effect on nasal mucosa in healthy volunteers].
The aim of the study was the clinical examinations of the tolerance and effect of Olbas oil on nasal mucosa in healthy volunteers during permanent 4 weeks administration. 23 healthy volunteers both sexes in the age between 20-50 were investigated. This investigations consisted of: history data, general and otorhinolaryngological examination, with particular evaluation of nasal mucosa, anterior rhinomanometry, olfactometry, saccharin translocation time, microbiological cultures, histamine nasal provocation test. Besides, each patient has follow up self evaluating chart of symptoms and adverse effect from the eyes, nose, pharynx and others. All the examined persons showed a very good tolerance of Olbas oil after 28 days of inhalation.
Kliniki Otolaryngologicznej Instytutu Chirurgii WAM w Lodzi.
A
A
Olszewska-Ziaber
P
P
Zalewski
J
J
Olszewski
H
H
Zielińska-Bliźniewska
P
P
Pietkiewicz
D000328:Adult; D004361:Drug Tolerance; D005260:Female; D006801:Humans; D008297:Male; D008365:Manometry / Q000379:methods; D008875:Middle Aged; D009297:Nasal Mucosa / Q000187:drug effects*; D015508:Nasal Obstruction / Q000188:drug therapy; D010938:Plant Oils / Q000494:pharmacology* / Q000627:therapeutic use
D010938:Plant Oils
Badania kliniczne nad tolerancja i wpływem olejku Olbas na błone şluzowa nosa u zdrowych ochotników.