Erythrokeratoderma variabilis: case report and review of the literature.
We report two patients, mother and daughter, with Erythrokeratoderma variabilis (EV). This rare genodermatosis is characterized by the presence of two components: migratory erythema and fixed hyperkeratosis. Our patients experienced symptomatic relief of pruritus associated with erythema with the use of an oral, low-sedating H1-antihistamine. Revision of the literature in order to allocate the frequency of pruritus in EV and discussion of this association will follow.
Dermatology Department, Churchill Hospital, Headington, Oxford, UK.
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Papadavid
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Koumantaki
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Dawber
D000293:Adolescent; D000328:Adult; D004890:Erythema / Q000150:complications* / Q000235:genetics / Q000473:pathology; D005260:Female; D006801:Humans; D007642:Keratosis / Q000150:complications* / Q000235:genetics / Q000473:pathology; D012867:Skin / Q000473:pathology