New goals for the U.S. Human Genome Project: 1998-2003.
The Human Genome Project has successfully completed all the major goals in its current 5-year plan, covering the period 1993-98. A new plan, for 1998-2003, is presented, in which human DNA sequencing will be the major emphasis. An ambitious schedule has been set to complete the full sequence by the end of 2003, 2 years ahead of previous projections. In the course of completing the sequence, a "working draft" of the human sequence will be produced by the end of 2001. The plan also includes goals for sequencing technology development; for studying human genome sequence variation; for developing technology for functional genomics; for completing the sequence of Caenorhabditis elegans and Drosophila melanogaster and starting the mouse genome; for studying the ethical, legal, and social implications of genome research; for bioinformatics and computational studies; and for training of genome scientists.
Collins
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National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA. fc23a@nih.gov
Patrinos
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Jordan
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Chakravarti
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A
Gesteland
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Walters
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D000818:Animals; D001675:Bioethics; D019295:Computational Biology; D016208:Databases, Factual; D030561:Databases, Nucleic Acid; D035082:Federal Government; D036281:Genetic Research; D014644:Genetic Variation; D016678:Genome; D015894:Genome, Human; D016045:Human Genome Project / Q000191:economics / Q000458:organization & administration; D006801:Humans; D033181:Information Dissemination; D007391:International Cooperation; D038622:Internationality; D008967:Molecular Biology / Q000193:education; D017354:Point Mutation; D011110:Polymorphism, Genetic; D017422:Sequence Analysis, DNA / Q000191:economics / Q000379:methods; D012961:Sociology; D013045:Species Specificity; D013997:Time Factors; D014481:United States