[Hyperthyroidism induced by iodinated roentgen contrast media].
Three patients with subclinical hyperthyroid goitre, women aged 63, 72 and 75 years following intravenous administration of an iodinated contrast medium developed hyperthyroidism with a marked rise of the concentration of free T4. Thyreostatic agents were unsuccessful in two patients, the third was left untreated. Hyperthyroidism improved spontaneously in all three. Iodine-induced hyperthyroidism is rare and is usually encountered in patients with a pre-existent autonomous thyroid function. Treatment of iodine-induced hyperthyroidism is essentially exclusively symptomatic. Prophylaxis with sodium perchlorate should be considered in cardiac patients with a goitre and a subnormal level of thyroid-stimulating hormone (TSH).
Academisch Ziekenhuis Vrije Universiteit, afd. Interne Geneeskunde, Amsterdam.
C
C
van Guldener
D M
DM
Blom
P
P
Lips
R J
RJ
Strack van Schijndel
D000368:Aged; D013956:Antithyroid Agents / Q000627:therapeutic use; D003287:Contrast Media / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology; D005260:Female; D006044:Goiter, Nodular / Q000175:diagnosis*; D006801:Humans; D006980:Hyperthyroidism / Q000139:chemically induced* / Q000628:therapy; D017613:Iodine Compounds / Q000009:adverse effects*; D008875:Middle Aged; D010472:Perchlorates / Q000627:therapeutic use; D012075:Remission, Spontaneous; D017670:Sodium Compounds / Q000627:therapeutic use
D013956:Antithyroid Agents; D003287:Contrast Media; D017613:Iodine Compounds; D010472:Perchlorates; D017670:Sodium Compounds; C031068:sodium perchlorate
Hyperthyreoïdie door jodiumhoudende röntgencontrastmiddelen.