Right-side neglect in Alzheimer's disease.
Unilateral neglect--the inability to pay attention to events occurring on one side of space--usually occurs for left-side events after focal right-hemisphere damage. We report a 73-year-old woman with probable AD and no evidence of focal brain lesions who showed signs of right-side neglect and extinction. Neglect was more severe after 1 year. Neuroimaging techniques demonstrated an asymmetry of cortical involvement, with cortical atrophy and hypoperfusion predominant in the left posterior regions. Unilateral neglect should be assessed systematically in AD.
Bartolomeo
P
P
INSERM Unit 324, Paris, France.
Dalla Barba
G
G
Boissé
M F
MF
Bachoud-Lévi
A C
AC
Degos
J D
JD
Boller
F
F
D000368:Aged; D000544:Alzheimer Disease / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology; D001288:Attention / Q000502:physiology*; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000503:physiopathology; D004292:Dominance, Cerebral / Q000502:physiology*; D005260:Female; D006801:Humans; D008609:Mental Status Schedule; D010468:Perceptual Disorders / Q000209:etiology* / Q000503:physiopathology; D011597:Psychomotor Performance; D013028:Space Perception / Q000502:physiology*; D015899:Tomography, Emission-Computed, Single-Photon