Transition mutations at CpG dinucleotides are the most frequent in vivo spontaneous single-based substitution mutation in the human HPRT gene.
O'Neill
J P
JP
Department of Medicine, University of Vermont College of Medicine, Burlington, USA. patrick.oneill@uvm.edu
Finette
B A
BA
D044503:5-Methylcytosine; D000328:Adult; D002648:Child; D018899:CpG Islands / Q000235:genetics*; D003596:Cytosine / Q000031:analogs & derivatives / Q000737:chemistry; D004252:DNA Mutational Analysis; D005260:Female; D006801:Humans; D007041:Hypoxanthine Phosphoribosyltransferase / Q000235:genetics*; D007231:Infant, Newborn; D007926:Lesch-Nyhan Syndrome / Q000235:genetics*; D008297:Male; D017354:Point Mutation
D044503:5-Methylcytosine; D003596:Cytosine; D007041:Hypoxanthine Phosphoribosyltransferase