[Protective effect of reduqing injection on rabbits with acute lung injury].
Acute lung injury (ALI) of rabbits was induced by endotoxin and the effects of Reduqing (RDQ) injection on the following indexes were studied. The results showed that the arterial blood pH, PCO2, lung/body index, lung wet/dry weight ratio, the protein and neutrophil contents in bronchoalveolar lavage fluid increased significently together with arterial PO2 marked drop, which were consistent with lung tissue damage, while administration of RDQ simultaneously ameliorated these changes. It is suggested that the Chinese herbal medicine RDQ injection could protect rabbit from the endotoxin-induced ALI.
Liu
H J
HJ
Department of Respiration, Union Hospital, Tongji Medical University, Wuhan.
Li
Y Q
YQ
Mao
W Q
WQ
D000818:Animals; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D004731:Endotoxins; D005260:Female; D008168:Lung / Q000473:pathology; D008297:Male; D009929:Organ Size; D011817:Rabbits; D012128:Respiratory Distress Syndrome / Q000139:chemically induced / Q000517:prevention & control*
D004365:Drugs, Chinese Herbal; D004731:Endotoxins