[The clinico-genetic characteristics of the origin and manifestation of colorectal cancer].
A clinical and genealogical investigation has been carried out in 169 subjects of both sexes, presenting with colorectal oncopathology. Particular features of the colorectal carcinoma in the patients have been recognized. The frequency of the tumours spread in the relatives of the probands is determined as is the spectrum of aggregation of large intestine carcinoma with neoplasia of other genesis in the pedigrees. The data obtained suggest an important contribution of genetic factors into the origination of colorectal carcinoma.
Nalieskina
L A
LA
Polishchuk
L Z
LZ
Oliĭnichenko
P I
PI
Hanina
K P
KP
Oliĭnichenko
H P
HP
Kukhar
I V
IV
Hlushchenko
N M
NM
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003111:Colonic Polyps / Q000175:diagnosis / Q000209:etiology / Q000235:genetics; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000209:etiology / Q000235:genetics*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000209:etiology / Q000235:genetics; D010375:Pedigree; D012737:Sex Factors
Kliniko-henetychni osoblyvosti vynnyknennia ta manifestatsiï kolorektal'noho raku.