Hydropic degenerating leiomyoma presenting as pseudo-Meigs syndrome with elevated CA 125.
BACKGROUND
Leiomyomas rarely cause pseudo-Meigs syndrome. Increased levels of CA 125 often are associated with some types of malignancy. No reported case of pseudo-Meigs syndrome presenting with hydropic degeneration of uterine leiomyoma and an elevated CA 125 level could be found on a MEDLINE search.


METHODS
A 46-year-old woman presented with a pleural effusion and a pelvic mass measuring 30 x 18 cm. Preoperative evaluation was remarkable for a CA 125 level of 254 U/mL. At laparotomy, the diagnosis was a benign leiomyoma with focal hyaline and extensive hydropic degeneration. Her pleural effusion resolved completely by 4 months postoperatively.


CONCLUSIONS
Pseudo-Meigs syndrome can present with an elevated CA 125 level.
Dunn
J S
JS
Department of Obstetrics and Gynecology, Keesler Medical Center, Kessler Air Force Base, Mississippi 39534, USA. jameydunn@aol.com
Anderson
C D
CD
Method
M W
MW
Brost
B C
BC
D018394:CA-125 Antigen / Q000097:blood*; D004487:Edema / Q000097:blood* / Q000150:complications; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000097:blood* / Q000150:complications / Q000175:diagnosis*; D008539:Meigs Syndrome / Q000097:blood* / Q000209:etiology*; D008875:Middle Aged; D014594:Uterine Neoplasms / Q000097:blood* / Q000150:complications / Q000175:diagnosis*
D018394:CA-125 Antigen