[Antisecretory effects of quamatel and gastrocepin in duodenal ulcer: comparison with intragastric pH-metry].
Antisecretory effect of intravenous quamatel (Q) and gastrocepin (G) was studied in 59 patients with duodenal ulcer. Mean maximal pH and delta-pH in antral portion of the stomach and its body were similar for Q and G, but pH responded to Q administration faster. The antisecretory effect of Q was more pronounced in males and young patients and was inversely proportional to initial acidity.
Sheptulin
A A
AA
Okhlobystin
A V
AV
D000293:Adolescent; D000328:Adult; D000368:Aged; D000897:Anti-Ulcer Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D004381:Duodenal Ulcer / Q000188:drug therapy* / Q000378:metabolism; D015738:Famotidine / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D005753:Gastric Mucosa / Q000187:drug effects / Q000378:metabolism; D006635:Histamine H2 Antagonists / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D006863:Hydrogen-Ion Concentration / Q000187:drug effects; D007275:Injections, Intravenous; D007419:Intestinal Secretions / Q000187:drug effects*; D008297:Male; D008875:Middle Aged; D010890:Pirenzepine / Q000008:administration & dosage / Q000627:therapeutic use*
D000897:Anti-Ulcer Agents; D006635:Histamine H2 Antagonists; D010890:Pirenzepine; D015738:Famotidine
Sravnitel'naia otsenka antisekretornogo deĭstviia kvamatela i gastrotsepina u bol'nykh iazvennoĭ bolezn'iu dvenadtsatiperstnoĭ kishki s pomoshch'iu vnutrizheludochnoĭ pH-metrii.