Description of two new isolates of Streptococcus pneumoniae in spain that are highly resistant to cefotaxime.
Two strains of Streptococcus pneumoniae isolated from sputum and bronchoalveolar samples with high-level resistance to cefotaxime (MIC = 8 to 16 microg/ml) are described. One of them, belonging to serogroup 19, was also highly resistant to penicillin (MIC = 16 microg/ml), while the other, of serogroup 14, was intermediate in its resistance to penicillin (MIC = 0.25 microg/ml). To our knowledge, these are the first two strains to be isolated in Spain with such high levels of resistance to cefotaxime.
Ruiz
J
J
Sección de Microbiología, Hospital Universitario Virgen de la Arrixaca, El Palmar 30120, Murcia, Spain. micro@isid.es
Sempere
M
M
Simarro
E
E
Fenoll
A
A
D000328:Adult; D000368:Aged; D002439:Cefotaxime / Q000494:pharmacology*; D002511:Cephalosporins / Q000494:pharmacology*; D004352:Drug Resistance, Microbial; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D013030:Spain; D013296:Streptococcus pneumoniae / Q000187:drug effects* / Q000302:isolation & purification
D002511:Cephalosporins; D002439:Cefotaxime