Clocks regulating developmental processes.
Developmental clocks are hypothetical embryonic time-measuring devices--some are run by oscillators, whereas others depend on rate-limiting processes. Their existence has been deduced from recent studies of the timing of the midblastula transition, the opening of the Hox cluster during organogenesis, and oligodendrocyte progenitor differentiation; however, the mechanisms underlying their function remain largely unknown.
Pourquié
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Laboratoire de Génétique et de Physiologie du Développement (LGPD), CNRS-INSERM-Université de la Méditerranée-AP de Marseille, France. pourquie@ibdm.univ-mrs.fr
D000818:Animals; D001683:Biological Clocks / Q000502:physiology*; D005314:Embryonic and Fetal Development / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental; D005801:Genes, Homeobox / Q000502:physiology*