Gonadotropin-releasing hormone deficiency in the human (idiopathic hypogonadotropic hypogonadism and Kallmann's syndrome): pathophysiological and genetic considerations.
Seminara
S B
SB
Department of Medicine, Massachusetts General Hospital, Boston 02114, USA.
Hayes
F J
FJ
Crowley
W F
WF
D000818:Animals; D057137:DAX-1 Orphan Nuclear Receptor; D004268:DNA-Binding Proteins / Q000737:chemistry; D003937:Diagnosis, Differential; D016326:Extracellular Matrix Proteins; D005260:Female; D008040:Genetic Linkage; D007987:Gonadotropin-Releasing Hormone / Q000172:deficiency* / Q000235:genetics / Q000502:physiology; D006062:Gonadotropins / Q000378:metabolism*; D006801:Humans; D007006:Hypogonadism / Q000235:genetics* / Q000503:physiopathology; D017436:Kallmann Syndrome / Q000235:genetics* / Q000503:physiopathology; D007986:Luteinizing Hormone / Q000378:metabolism; D008297:Male; D009419:Nerve Tissue Proteins / Q000737:chemistry; D000857:Olfaction Disorders / Q000235:genetics / Q000503:physiopathology; D010375:Pedigree; D011247:Pregnancy; D018168:Receptors, Retinoic Acid / Q000737:chemistry; D012097:Repressor Proteins; D014157:Transcription Factors / Q000737:chemistry; D014960:X Chromosome / Q000235:genetics / Q000502:physiology
C076266:ANOS1 protein, human; D057137:DAX-1 Orphan Nuclear Receptor; D004268:DNA-Binding Proteins; D016326:Extracellular Matrix Proteins; D006062:Gonadotropins; C539965:NR0B1 protein, human; D009419:Nerve Tissue Proteins; D018168:Receptors, Retinoic Acid; D012097:Repressor Proteins; D014157:Transcription Factors; D007987:Gonadotropin-Releasing Hormone; D007986:Luteinizing Hormone