[Relationship between the onset and outcome of interstitial pneumonia associated with polymyositis and dermatomyositis].
We investigated the outcome of 12 patients with interstitial pneumonia (IP) associated with polymyositis and dermatomyositis (PM/DM). The mean age of the patients was 53. There were 3 cases of PM/DM preceding the respiratory symptoms (RS), 7 cases of simultaneous PM/DM and RS, and 2 cases of PM/DM delayed with RS. In these 3 groups, there was a tendency for cases with PM/DM preceding RS to be younger. Jo-1 antibody was positive in only one case of the simultaneous group. Patients in whom IP preceded PM/DM or was simultaneous with PM/DM showed a better response to corticosteroid. The chest CT findings and TBLB findings showed a BOOP pattern in these patients. TBLB findings are not useful for diagnosing the pathological type, however they are useful for evaluating the effectiveness of steroid therapy on IP in PM/DM.
Saku
N
N
Department of Pulmonary Medicine, Jichi Medical School, Tochigi, Japan.
Ohno
S
S
Sugiyama
Y
Y
Kitamura
S
S
D000328:Adult; D000368:Aged; D003882:Dermatomyositis / Q000150:complications*; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000150:complications* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D017285:Polymyositis / Q000150:complications*