title: Enterotoxigenic Clostridium perfringens type A necrotic enteritis in a foal.
abstract: A Thoroughbred-Quarter Horse crossbred foal developed hemorrhagic enteritis and died < 48 hours after birth. Gross and histologic findings were suggestive of Clostridium perfringens type C infection, and large numbers of C perfringens were isolated from intestinal contents. However, genotyping of isolates indicated that they were enterotoxigenic C perfringens type A, and isolates were found to produce C perfringens enterotoxin in vitro. This case suggests that enterotoxigenic C perfringens type A may cause enteric disease in horses.
authors.affiliation: Department of Veterinary Science and Microbiology, University of Arizona, Tucson 85721, USA.
authors.forename: D
authors.initials: D
authors.lastname: Bueschel
authors.forename: R
authors.initials: R
authors.lastname: Walker
authors.forename: L
authors.initials: L
authors.lastname: Woods
authors.forename: J
authors.initials: J
authors.lastname: Kokai-Kun
authors.forename: B
authors.initials: B
authors.lastname: McClane
authors.forename: J G
authors.initials: JG
authors.lastname: Songer
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D015153:Blotting, Western / Q000662:veterinary; D003015:Clostridium Infections / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D003016:Clostridium perfringens / Q000145:classification* / Q000235:genetics / Q000378:metabolism; D004751:Enteritis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D004768:Enterotoxins / Q000032:analysis / Q000096:biosynthesis* / Q000235:genetics; D005838:Genotype; D006734:Horse Diseases / Q000382:microbiology* / Q000473:pathology; D006736:Horses; D007422:Intestines / Q000737:chemistry / Q000382:microbiology / Q000473:pathology; D009336:Necrosis
chemical_list: D004768:Enterotoxins; C035598:enterotoxin, Clostridium