Vesicle formation: dynamic dynamin lives up to its name.
The GTP-binding protein dynamin was initially thought to be required for just the final stages of clathrin-dependent vesicle formation, but recent results indicate that it can actually catalyse many of the essential steps in the vesiculation pathway.
Kirchhausen
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Department of Cell Biology and Center for Blood Research, Harvard Medical School, Boston, Massachusetts 02115, USA. kirchhausen@crystal.harvard.edu
D000818:Animals; D018699:Coated Vesicles / Q000502:physiology*; D034281:Dynamins; D020558:GTP Phosphohydrolases / Q000235:genetics / Q000502:physiology*; D019204:GTP-Binding Proteins / Q000235:genetics / Q000502:physiology*; D009419:Nerve Tissue Proteins / Q000378:metabolism; D013572:Synaptic Vesicles / Q000502:physiology*
D009419:Nerve Tissue Proteins; C075637:amphiphysin; D020558:GTP Phosphohydrolases; D019204:GTP-Binding Proteins; D034281:Dynamins