[The effect of chaihu qingxin yin on left cardiac function and T-cell subgroup in peripheral blood in children with viral myocarditis].
OBJECTIVE
To observe the effect of Caihu Qingxin Yin (CHQXY) in treating viral myocarditis.


METHODS
CHQXY was used to treat 52 cases of acute viral myocarditis in children, compared with the routine method using energy mixture in 32 patients.


RESULTS
(1) The total effective rate of 52 patients using CHQXY was 71.2% which was higher than that of the control group in 32 patients with 53.1%, Ridit analysis, P < 0.01. (2) Functional shortaxial shortening rate (FS) and ejecting fraction (EF) in CHQXY group were superior to those of the control group, P < 0.01. (3) CHQXY might modulate the immune function of T lymphocyte, enabled the CD3 and ratio of CD4/CD8 tended to normalize.


CONCLUSIONS
CHQXY played an important role in the treatment of viral myocarditis with the mechanism of improving the left cardiac function and modulating celluar immune function.
Wang
X F
XF
Liaoning College of Traditional Chinese Medicine, Shenyang.
Yan
W C
WC
Guo
Z W
ZW
D000293:Adolescent; D000998:Antiviral Agents / Q000494:pharmacology; D016516:CD4-CD8 Ratio; D002648:Child; D002675:Child, Preschool; D003384:Coxsackievirus Infections / Q000276:immunology / Q000503:physiopathology*; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D029822:Enterovirus B, Human; D005260:Female; D006801:Humans; D008297:Male; D009205:Myocarditis / Q000276:immunology / Q000503:physiopathology* / Q000821:virology; D016176:T-Lymphocyte Subsets / Q000187:drug effects*; D016277:Ventricular Function, Left / Q000187:drug effects*
D000998:Antiviral Agents; D004365:Drugs, Chinese Herbal