[Apoptosis in the male gonad].
Self-destruction of a cell following an internal or exogenous stimulus was a major concept which emerged in the early seventies. Such a phenomena is now reported to influence both embryonic development and tissue growth or renewing. Tumor growth as well as treatment may depend on apoptosis. This phenomena is identified using morphological as well as biochemical criteria. Spermatogenesis is a target for apoptosis which participate in the regulation of sperm production. Endocrine control of apoptosis in the seminiferous tubule was thoroughly studied, and some mechanistical studies dealing with oncogenes involved in apoptosis control have been done. Apoptosis is a key phenomenon in the control of sperm production.
Royère
D
D
Dept. Obs-Gyn & Reprod. Humaine, CHU, Faculté de Médecine, Tours.
Guerif
F
F
Rochereau de Reviers
M T
MT
Panthier
S
S
Lansac
J
J
D000818:Animals; D017209:Apoptosis / Q000235:genetics / Q000502:physiology*; D053938:DNA Fragmentation; D005640:Follicle Stimulating Hormone / Q000502:physiology; D006801:Humans; D008297:Male; D051381:Rats; D012671:Seminiferous Tubules / Q000502:physiology; D013091:Spermatogenesis / Q000502:physiology*; D013739:Testosterone / Q000502:physiology
D013739:Testosterone; D005640:Follicle Stimulating Hormone