Xanthine urolithiasis in a dachshund.
Calculi were located in the kidneys, the ureters and the bladder of a two-year-old male dachshund. The yellow-greenish calculi developed as a result of impaired transformation of xanthine to uric acid resulting in an increased concentration of xanthine in the urine. The cause of the impaired catabolism of xanthine was probably a disorder of the xanthine oxidase enzyme, which catalyses the transformation of xanthine to uric acid.
Flegel
T
T
Department of Veterinary Surgery, School of Veterinary Medicine, Free University, Berlin, Germany.
Freistadt
R
R
Haider
W
W
D000818:Animals; D004283:Dog Diseases / Q000201:enzymology* / Q000473:pathology; D004285:Dogs; D008297:Male; D014527:Uric Acid; D014545:Urinary Calculi / Q000201:enzymology / Q000473:pathology / Q000662:veterinary*; D019820:Xanthine / Q000378:metabolism*; D014969:Xanthine Oxidase / Q000378:metabolism
D019820:Xanthine; D014527:Uric Acid; D014969:Xanthine Oxidase