Retinoids and vitamin D analogues: action on nuclear transcription.
Receptors for retinoids and vitamin D belong to the superfamily of ligand-dependent nuclear transcription factors. Development of topical and systemic retinoids and topical vitamin D3 analogues is revolutionizing dermatological therapy, particularly the management of acne, psoriasis, ichythyoses, photoageing and skin cancer.
Griffiths
C E
CE
Section of Dermatology, University of Manchester, Hope Hospital, Salford.
D006801:Humans; D008024:Ligands; D012176:Retinoids / Q000009:adverse effects / Q000627:therapeutic use*; D012871:Skin Diseases / Q000188:drug therapy*; D012878:Skin Neoplasms / Q000188:drug therapy; D014157:Transcription Factors; D014158:Transcription, Genetic; D014801:Vitamin A / Q000031:analogs & derivatives / Q000627:therapeutic use*; D014807:Vitamin D / Q000031:analogs & derivatives / Q000627:therapeutic use*
D008024:Ligands; D012176:Retinoids; D014157:Transcription Factors; D014801:Vitamin A; D014807:Vitamin D