title: Annular elastolytic giant cell granuloma.
abstract: A 49-year-old woman had large annular lesions with raised erythematous borders and atrophic, hypopigmented central regions on her neck, trunk, and proximal upper extremities. Examination of a biopsy specimen demonstrated a granulomatous infiltrate in the upper dermis that surrounded areas lacking elastic fibers; elastic fibers were present within the multinucleated giant cells. The clinical presentation and pathologic findings were consistent with a diagnosis of annular elastolytic giant cell granuloma (AEGCG). The clinical description and pathologic differential diagnosis of AEGCG are reviewed.
authors.affiliation: Vascular Cell Biology Laboratory, Texas Heart Institute, Houston, USA.
authors.forename: C L
authors.initials: CL
authors.lastname: Tock
authors.forename: P R
authors.initials: PR
authors.lastname: Cohen
mesh_terms: D001132:Arm; D003937:Diagnosis, Differential; D005260:Female; D016460:Granuloma Annulare / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D008875:Middle Aged; D009333:Neck; D013909:Thorax