Apoptosis detection: an overview.
As the analysis of apoptosis is of interest in many basic and clinically oriented investigations, we intend to give a brief overview on the recently most-used methods for detection of apoptotic cells, including the study of morphology, analysis of DNA degradation, DNA end-labeling techniques, flow cytometric analysis, and nuclease assays. Features and advantages of the different methods are discussed.
Sgonc
R
R
Institute for General and Experimental Pathology, University of Innsbruck, Medical School, Austria. roswitha.sgonc@uibk.ac.at
Gruber
J
J
D017209:Apoptosis; D053938:DNA Fragmentation; D004720:Endonucleases / Q000032:analysis; D005434:Flow Cytometry; D006801:Humans; D020287:In Situ Nick-End Labeling
D004720:Endonucleases