[Recent findings in the etiopathogenesis of caries].
Caries have three main interrelated etiological factors: 1) a bacteriological factor represented by cariogen oral bacteria, mainly Streptococcus mutans, which adhere to the dental surface and initiate the decalcification of the enamel by producing an acid environment through carbohydrate degradation; 2) the quality of the oral biofilm which is colonized more or less rapidly by bacteria after brushing, leading to an adhesive and aggressive dental plaque; 3) the quality of enamel which is reinforced by fluor ion, and of saliva. The early superficial phase of carie constitution is reversible through remineralisation from calcium, phosphate and fluor ions present in the oral cavity. In the absence of remineralisation the destructive and infectious process extends to the inner part of the tooth leading, to its progressive destruction. Prevention is based upon the following pathophysiological data, mainly: 1) family education on oral hygiene by regular brushing, and avoidance of foods or fluids containing sugars between meals; 2) fluoride intake starting at birth and being adapted to age, the prescription of fluoride supplementation, taking into account possible other sources of fluor (salt, water).
Farge
P
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Faculté d'odontologie, université Claude-Bernard, Lyon I, France.
D001422:Bacterial Adhesion; D001424:Bacterial Infections / Q000150:complications; D018441:Biofilms; D002648:Child; D003731:Dental Caries / Q000209:etiology* / Q000503:physiopathology* / Q000517:prevention & control; D003773:Dental Plaque / Q000503:physiopathology; D006801:Humans; D012463:Saliva / Q000502:physiology; D013290:Streptococcal Infections / Q000150:complications; D013295:Streptococcus mutans