title: Ventricular tachycardia after oxytocin injection in patients with prolonged Q-T interval syndrome--report of two cases.
abstract: Oxytocin is widely used in obstetric settings to stimulate uterine contraction and prevent postpartum hemorrhage. Its adverse effects which include transient hypotension and increase heart rate could be life-threatening in patients with fixed cardiac output or hypotension resulting from hemorrhage. We reported two cases suspected to have preexisting prolonged Q-T interval syndrome (PQTS) who developed ventricular tachycardia immediately after intravenous injection of oxytocin. Anesthetic management of and use of oxytocic agents in patients with PQTS were discussed.
authors.affiliation: Department of Anesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan, R.O.C.
authors.forename: S C
authors.initials: SC
authors.lastname: Liou
authors.forename: C
authors.initials: C
authors.lastname: Chen
authors.forename: S Y
authors.initials: SY
authors.lastname: Wong
authors.forename: K M
authors.initials: KM
authors.lastname: Wong
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008133:Long QT Syndrome / Q000150:complications*; D010121:Oxytocin / Q000009:adverse effects*; D017180:Tachycardia, Ventricular / Q000139:chemically induced*
chemical_list: D010121:Oxytocin