[The induction and the prevention of Vi antigen of S.typhi loss by three metalic ions of salts].
Three metalic salts Ferrous, Mgnesium and Calcium were used to induce and to prevent Vi antigen of S. typhi loss. All of the 96 Vi-II phage typing standard strains belonged to V type (a recovery rate of 100%). Out of 1320 local strains, 1292 were type V (a recovery rate of 97.7%) and 28 remained type W with a Vi loss rate of 2.1%. The results showed that induction and prevention of Vi antigen of S. typhi loss by the three metalic salts was higher than that of other reports which showed a loss rate of 5% Vi antigen of S. typhi.
Zhang
J X
JX
Dept. of Microboilogy, Beijing Medical University.
Cao
J
J
Tu
J
J
D000818:Animals; D000940:Antigenic Variation / Q000187:drug effects*; D000942:Antigens, Bacterial / Q000187:drug effects* / Q000276:immunology; D002118:Calcium / Q000494:pharmacology*; D003470:Culture Media; D005296:Ferrous Compounds / Q000494:pharmacology; D006801:Humans; D008278:Magnesium Sulfate / Q000494:pharmacology*; D011135:Polysaccharides, Bacterial / Q000187:drug effects* / Q000276:immunology; D012485:Salmonella typhi / Q000276:immunology*
D000942:Antigens, Bacterial; D003470:Culture Media; D005296:Ferrous Compounds; D011135:Polysaccharides, Bacterial; C020748:ferrous sulfate; D008278:Magnesium Sulfate; D002118:Calcium