title: How significant is magnesium in thermoregulation?
abstract: Nine apparently healthy male subjects, mean age 22.8 yr, SD 4.1, free from disease, medication or addiction who gave informed consent, underwent acclimation process in a heat chamber; exposed during 2 h daily for 10 consecutive days to a temperature of 40 degrees C and 40% relative humidity while walking on a treadmill elevated by 3 degrees at a speed of 5 km/h (VO2 1.2 1.min-1). Serum, mononuclear and erythrocyte magnesium (S-Mg, M-Mg and E-Mg, respectively) were monitored on day 1, 5 and 10 before and after the heat exposure. S-Mg decreased while M-Mg increased after the heat exposures, suggesting a shift of S-Mg to mononuclear cells. The decrease of S-Mg was sustained at the end of the acclimation process. E-Mg increased up to day 5 and decreased gradually approximating the baseline by day 10. Mg appears to play a significant role in heat acclimation.
authors.affiliation: Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel-Aviv University, Tel Hashomer, Israel.
authors.forename: G
authors.initials: G
authors.lastname: Stendig-Lindberg
authors.forename: D
authors.initials: D
authors.lastname: Moran
authors.forename: Y
authors.initials: Y
authors.lastname: Shapiro
mesh_terms: D000328:Adult; D001833:Body Temperature Regulation / Q000502:physiology*; D004912:Erythrocytes / Q000378:metabolism; D015444:Exercise; D018882:Heat Stress Disorders / Q000097:blood*; D006801:Humans; D007963:Leukocytes, Mononuclear / Q000378:metabolism; D008274:Magnesium / Q000097:blood*; D008297:Male; D005082:Physical Exertion / Q000502:physiology
chemical_list: D008274:Magnesium