Distribution of amiloride-sensitive sodium channels in the oral cavity of the hamster.
The distribution of amiloride-sensitive sodium channels (ASSCs) in taste buds isolated from the oral cavity of hamsters was assessed by patch clamp recording. In contrast to the case for rats, taste cells from the fungiform, foliate and vallate papillae and from the soft palate all contain functional ASSCs. The differential distribution of ASSCs between the hamster and the rat may be important for understanding the physiology underlying the differing behavioral responses of these species to sodium salts.
Gilbertson
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Pennington Biomedical Research Center, Louisiana State University, Baton Rouge 70808-4124, USA. tim.gilbertson@tasteful.com
Fontenot
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D000584:Amiloride / Q000494:pharmacology*; D000818:Animals; D006224:Cricetinae; D008297:Male; D008647:Mesocricetus; D018408:Patch-Clamp Techniques; D015222:Sodium Channels / Q000187:drug effects* / Q000378:metabolism; D013650:Taste Buds / Q000378:metabolism*
D015222:Sodium Channels; D000584:Amiloride