Comparison of the DNA content in recurrent and nonrecurrent basaliomas of the face.
The ploidy status of 5 recurrent and 7 nonrecurrent basaliomas was investigated using a CAS 200 image analyser. All recurrent basaliomas were aneuploid in contrast to nonrecurrent ones representing the euploid status. The percentage of cells in S phase in recurrent basaliomas was twice as high as in nonrecurrent ones. The authors conclude that aneuploidy in primary tumour can be a warning signal for recurrences and these patients should undergo special control.
Brinck
U
U
Department of Pathology, Georg August University, Goettingen, Germany.
Korabiowska
M
M
Knapik
J
J
Ruschenburg
I
I
Trybus-Gałuszka
H
H
Bartkowski
S B
SB
Stachura
J
J
D000368:Aged; D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000235:genetics* / Q000473:pathology; D005153:Facial Neoplasms / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000235:genetics*; D009669:Nose Neoplasms / Q000235:genetics* / Q000473:pathology; D011003:Ploidies