Effect of intraocular acetylcholine and carbachol on the corneal endothelium. In vivo comparative study.
The purpose of this study is to evaluate differences in corneal endothelial cell loss after intraocular use of two different miotics in subjects who have undergone extracapsular cataract extraction with posterior chamber intraocular lens implantation. The patients were divided into two groups: the first received 1 ml of 1% acetylcholine chloride and the second 0.5 ml of 0.01% carbachol as intraocular miotics. The endothelial count was done preoperatively and then 1 month after cataract extraction. There were no statistically significant differences in the mean cell loss between both groups. The authors believe that both miotics could be used in cataract surgery.
Roszkowska
A M
AM
Institute of Ophthalmology, Messina, Italy.
Ferreri
G
G
Squeri
C A
CA
D'Angelo
P
P
Ferreri
F M
FM
D000109:Acetylcholine / Q000008:administration & dosage* / Q000627:therapeutic use; D000368:Aged; D002217:Carbachol / Q000008:administration & dosage* / Q000627:therapeutic use; D002387:Cataract Extraction; D002452:Cell Count; D004728:Endothelium, Corneal / Q000187:drug effects* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008916:Miotics / Q000008:administration & dosage* / Q000627:therapeutic use; D009883:Ophthalmic Solutions; D011182:Postoperative Care; D011184:Postoperative Period
D008916:Miotics; D009883:Ophthalmic Solutions; D002217:Carbachol; D000109:Acetylcholine