[Development of non-iodized oily agent in targeting chemoembolization for hepatocellular carcinoma].
The purpose of this study was to evaluate a new oily agent in targeting chemoembilization for hepatocellular carcinoma. The oily preparation was made by mixing non-iodinated poppy seed oil and a thickener to obtain the same viscosity as Lipiodol. The oily preparation and Lipiodol were compared by injecting them into the hepatic artery of rabbits inoculated with VX 2 carcinoma in their liver. On the CT scan following intra-arterial injection, tumors were visibly stained in the non-iodinated preparation group, whereas the Lipiodol group was not evaluable because of excessively high attenuation. The non-iodinated oily preparation was concluded to be of clinical significance.
Hamuro
M
M
Department of Radiology, Osaka City University Medical School.
Nakamura
K
K
Sakai
Y
Y
Kobashi
S
S
Iuchi
T
T
Nanata
M
M
Nishida
N
N
Kaminou
T
T
Matsuoka
T
T
Takashima
S
S
Yamada
R
R
D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000628:therapy*; D016461:Chemoembolization, Therapeutic; D008113:Liver Neoplasms / Q000628:therapy*; D009821:Oils / Q000008:administration & dosage; D011817:Rabbits
D009821:Oils