title: Early post-radiation changes of red blood cell shape in rats.
abstract: Scanning electron microscopy (SEM) of red blood cells in whole blood samples from rats was performed following acute gamma-irradiation of animals with 0.25 to 1 Gy. Increased incidence of echinocytosis was observed and found to be dose- and time-dependent. At a higher radiation dose (1 Gy), echinocytosis was revealed within 5 minutes after treatment and persisted up to 3 weeks. The data demonstrate the applicability of SEM for detecting minimal radiation-induced lesions of red blood cells.
authors.affiliation: Primorsky Health Rehabilitation Center, St. Petersburg, Russia. vna@camt.spb.su
authors.forename: V D
authors.initials: VD
authors.lastname: Zharskaya
authors.forename: A B
authors.initials: AB
authors.lastname: Chukhlovin
mesh_terms: D000818:Animals; D004307:Dose-Response Relationship, Radiation; D004912:Erythrocytes / Q000528:radiation effects* / Q000648:ultrastructure; D005720:Gamma Rays; D008855:Microscopy, Electron, Scanning; D051381:Rats; D017208:Rats, Wistar