title: [Effect of adrenomedullin on mesenteric microvessels and microlymphatics in rat].
abstract: The dilatant effect of adrenomedullin (ADM), a novel peptide of 52 amino acids, on the mesenteric microvessels and microlymphatics was investigated under microscopic observation. 10(-6) mol/L ADM could also ameliorate alteration of the hemorheology induced by 10(-5) mol/L norepinephrine (NE) or 10(-7) mol/L endothelin (ET). However, this ameliorative response was markedly inhibited in the presence of NG-nitro-L-arginine (L-NNA), an inhibitor for production of nitric oxide.
authors.affiliation: Department of Pathophysiology, Zhangjiakou Medical College.
authors.forename: G
authors.initials: G
authors.lastname: Fan
authors.forename: C Y
authors.initials: CY
authors.lastname: Niu
authors.forename: M
authors.initials: M
authors.lastname: Han
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.forename: Y J
authors.initials: YJ
authors.lastname: Wei
authors.forename: S S
authors.initials: SS
authors.lastname: Tang
authors.forename: J
authors.initials: J
authors.lastname: Tang
mesh_terms: D053607:Adrenomedullin; D000818:Animals; D002196:Capillaries / Q000187:drug effects; D016232:Endothelins / Q000494:pharmacology; D008208:Lymphatic System / Q000187:drug effects; D008297:Male; D008643:Mesentery / Q000098:blood supply*; D019335:Nitroarginine / Q000494:pharmacology; D009638:Norepinephrine / Q000494:pharmacology; D010455:Peptides / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D014665:Vasodilator Agents / Q000494:pharmacology*
chemical_list: D016232:Endothelins; D010455:Peptides; D014665:Vasodilator Agents; D053607:Adrenomedullin; D019335:Nitroarginine; D009638:Norepinephrine