title: Treatment of spider veins with the 595 nm pulsed-dye laser.
abstract: BACKGROUND
  Previous attempts to treat spider veins with the conventional 585 nm pulsed-dye laser with a 0.5-ms pulse duration have been relatively ineffective. Recently, a new pulsed-dye laser that is tunable from 585 to 600 nm with a pulse duration 3 times longer than previously available lasers has preliminarily been shown to be effective for treatment of spider veins.
  
  
  OBJECTIVE
  Our purpose was to evaluate the effectiveness of multiple treatments with the tunable long-pulse dye laser in treatment of spider veins of the lower extremity.
  
  
  METHODS
  Ten female volunteers were treated in two separate areas containing blue or red linear spider veins less than 1.5 mm in diameter. Treatments were administered with the pulsed-dye laser with a 1.5-ms pulse duration and 595-nm light at fluences of 15 and 20 J/cm2, and each subject received a total of 3 treatments at each site, administered at 6-week intervals. Photographs were taken before and 6 weeks after the last treatment.
  
  
  RESULTS
  Computer-based image analysis showed clearing of more than three fourths of veins after 3 treatments with 15 or 20 J/cm2. Side effects were minimal and the treatments were well tolerated.
  
  
  CONCLUSIONS
  The 595 nm, 1.5 ms pulse duration, pulsed-dye laser is safe and effective for treating blue or red spider veins of the lower extremities less than 1.5 mm in diameter in nontanned patients with Fitzpatrick skin types I and II. Multiple treatments improve on the results obtained after a single treatment.
authors.affiliation: Department of Dermatology and Cutaneous Biology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania 19107-5541, USA. Bernste1@jeflin.tju.edu
authors.forename: E F
authors.initials: EF
authors.lastname: Bernstein
authors.forename: J
authors.initials: J
authors.lastname: Lee
authors.forename: J
authors.initials: J
authors.lastname: Lowery
authors.forename: D B
authors.initials: DB
authors.lastname: Brown
authors.forename: R
authors.initials: R
authors.lastname: Geronemus
authors.forename: G
authors.initials: G
authors.lastname: Lask
authors.forename: J
authors.initials: J
authors.lastname: Hsia
mesh_terms: D000328:Adult; D000368:Aged; D004487:Edema / Q000209:etiology; D005069:Evaluation Studies as Topic; D005260:Female; D006801:Humans; D017495:Hyperpigmentation / Q000209:etiology; D017496:Hypopigmentation / Q000209:etiology; D007091:Image Processing, Computer-Assisted; D017075:Laser Coagulation / Q000009:adverse effects / Q000379:methods*; D007866:Leg / Q000098:blood supply*; D008875:Middle Aged; D010149:Postoperative Pain / Q000209:etiology; D011693:Purpura / Q000209:etiology; D012449:Safety; D013684:Telangiectasis / Q000473:pathology / Q000601:surgery*; D013997:Time Factors; D014680:Veins / Q000473:pathology