Amino acid substitutions at positions 69, 165, 244 and 275 of the PER-1beta-lactamase do not impair enzyme inactivation by clavulanate.
Bouthors
A T
AT
Jarlier
V
V
Sougakoff
W
W
D019943:Amino Acid Substitution; D019818:Clavulanic Acid / Q000494:pharmacology*; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D004794:Enzyme Repression; D004926:Escherichia coli / Q000201:enzymology / Q000235:genetics; D009154:Mutation; D065093:beta-Lactamase Inhibitors; D001618:beta-Lactamases / Q000235:genetics
D004791:Enzyme Inhibitors; D065093:beta-Lactamase Inhibitors; D019818:Clavulanic Acid; D001618:beta-Lactamases