title: [Neonatal lupus erythematosis and atrial-ventricular block. A case report and review of the literature].
abstract: Neonatal lupus erythematosus is a rare syndrome. It is characterized by a transient lupus dermatitis and congenital heart block. The immunopathogenesis of the disease has been linked to the presence of the SSA antibody. In this report, we describe a symptomatic congenital heart block in a 13-year-old male whose mother had documented systemic lupus erythematosus. We also discuss how to manage a woman with lupus erythematosus and positive antiSSA/Ro antibodies. We conclude that patients with neonatal lupus and their mothers should be observed closely before delivery and for prolonged periods for signs of active disease.
authors.affiliation: Service de Médecine interne, Université Saint-Joseph, Faculté de Médecine (USJ-FM), Beyrouth, Liban.
authors.forename: E
authors.initials: E
authors.lastname: Ghayad
authors.forename: F
authors.initials: F
authors.lastname: Haddad
authors.forename: A
authors.initials: A
authors.lastname: Tohme
authors.forename: E
authors.initials: E
authors.lastname: Salame
mesh_terms: D000293:Adolescent; D005260:Female; D006327:Heart Block / Q000151:congenital* / Q000276:immunology; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000151:congenital* / Q000276:immunology; D008180:Lupus Erythematosus, Systemic / Q000628:therapy; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000628:therapy