[Temporal lobe epilepsy and ganglioglioma in children. Clinical aspects, imagery and neuropathology; nosological discussion of six cases].
BACKGROUND
Gangliogliomas belong to debated nosological entity. They are classified as neuronal or neuroglial tumors.


METHODS
Six children aged from 4 months to 15 years (mean age: 4 years and 6 months) were initially seen for partial seizures resistant to treatment. Tumoral resection was performed in all six. Diagnosis was made from immunohistological study of the tumor.


CONCLUSIONS
Gangliogliomas are non-malignant, with a good prognosis, even if inaugural clinical manifestations are severe. Neuroradiological diagnosis with astrocytomas and cortical dysplasia is not easy, and pathological distinction from cortical dysplasia is difficult.


CONCLUSIONS
The immunohistochemical confirmation of diagnosis permits a logical therapeutic attitude: complete resection of tumor is followed by an excellent outcome.
Brissaud
O
O
Unité de neurologie pédiatrique, hôpital des enfants Pellegrin, Bordeaux, France.
Pedespan
J M
JM
Chateil
J F
JF
Loiseau
H
H
Dautheribes
M
M
Wardi
Y
Y
Brun
M
M
Rougier
A
A
D000293:Adolescent; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D004833:Epilepsy, Temporal Lobe / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D005260:Female; D018303:Ganglioglioma / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D006801:Humans; D007223:Infant; D008297:Male; D014057:Tomography, X-Ray Computed