[Endo- and ectoparasites as factors influencing variability of the humoral immunity response in a natural population of red vole (Clethrionomys rutilus)].
Based on the five-year population study of red voles Clethrionomys rutilus Pallas in southern West Siberia, we analysed the distribution of two predominating species of parasites (tapeworms Hymenolepis horrida and immature instars of ticks Ixodes persulcatus) in different demographic groups of the host, and seasonal changes of their incidence in the population. We assessed primary humoral immune response of the voles (splenic antibody-forming cells) to antigenic challenge (injection of sheep erythrocytes) in respect to occurrence of these parasites. It was revealed that infection with H. horrida significantly reduced the numbers of antibody-forming cells in immature summer-born voles. In contrast, immune responses in immature and mature voles, which where parasitized by I. persulcatus at the moment of capture, were significantly higher as compared to non-infected hosts. The possible mechanisms of influence of parasites on variability of immune reactions of voles in the population under study are discussed.
Dobrotvorskiĭ
A K
AK
Moshkin
M P
MP
Chechulin
A I
AI
Panov
V V
VV
Mak
V V
VV
D000818:Animals; D000909:Antibodies, Helminth / Q000096:biosynthesis*; D000917:Antibody Formation; D003411:Arvicolinae / Q000276:immunology / Q000469:parasitology*; D004912:Erythrocytes / Q000276:immunology; D006926:Hymenolepis / Q000276:immunology*; D018884:Ixodes / Q000276:immunology*; D012307:Risk Factors; D012756:Sheep; D013045:Species Specificity
D000909:Antibodies, Helminth