title: [Successful multidisciplinary treatment for bladder cancer with priapism. A case report].
abstract: A 44-year-old man suspected of having transitional cell carcinoma (TCC) of the prostate was referred to our hospital. He had a painful semi-erect penis at his first visit. Then needle biopsy of the corpus cavernosum histologically revealed metastatic TCC. CT of the pelvis showed bilateral ureteral obstruction caused by the advanced tumor but no lymph node swelling was found. Under the diagnosis of prostatic TCC with penile metastasis, bilateral percutaneous nephrostomy followed by two courses of combination chemotherapy (IFEP regimen) was carried out, which resulted in the disappearance of priapism. Radical cystectomy with total penectomy was performed. The final pathological diagnosis was corrected to TCC of the urinary bladder with invasion to the prostate and metastasis of the corpus cavernosum and the right obturator lymph node. Enlargement of the prostate proved to be caused by glandular hyperplasia with atypical hyperplasia of the prostate gland. Three courses of adjvent IFEP chemotherapy was given post-operatively and he has been alive with no evidence of the disease for 10 months.
authors.forename: S
authors.initials: S
authors.lastname: Kitsukawa
authors.forename: T
authors.initials: T
authors.lastname: Kinn
authors.forename: T
authors.initials: T
authors.lastname: Yoshida
authors.forename: J
authors.initials: J
authors.lastname: Yonese
authors.forename: T
authors.initials: T
authors.lastname: Izutami
authors.forename: I
authors.initials: I
authors.lastname: Fukui
authors.forename: Y
authors.initials: Y
authors.lastname: Ishikawa
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002295:Carcinoma, Transitional Cell / Q000556:secondary* / Q000628:therapy*; D002945:Cisplatin / Q000008:administration & dosage; D003131:Combined Modality Therapy; D015653:Cystectomy; D005472:Fluorouracil / Q000008:administration & dosage; D006801:Humans; D007069:Ifosfamide / Q000008:administration & dosage; D008207:Lymphatic Metastasis; D008297:Male; D009361:Neoplasm Invasiveness; D010412:Penile Neoplasms / Q000556:secondary* / Q000628:therapy*; D011317:Priapism / Q000209:etiology*; D011470:Prostatic Hyperplasia / Q000473:pathology; D011471:Prostatic Neoplasms / Q000473:pathology; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000628:therapy
chemical_list: D002945:Cisplatin; D005472:Fluorouracil; D007069:Ifosfamide