title: [The prevention of autoimmune kidney lesions developing in long-term exposure to epoxy compounds].
abstract: Clinical and biochemical, immunological and histological studies made in animals under inhalation exposure to volatile components of a new epoxy resin have yielded evidence in support of the development of autoimmune pathology (glomerulonephritis). One-stage determination of the amount of the blood serum circulating immune complexes and of the degree of sensibilization of bodily immunocompetent cells to a chemical (epichlorhydrin) and tissue (kidney) allergens in whole blood are regarded as a test for early diagnosis of glomerulonephritis. The enterosorbent "Ensoral" inhibits the development of those autoimmune processes being caused by bodily exposure to high concentrations of volatile components of epoxy resins.
authors.forename: Ia B
authors.initials: IaB
authors.lastname: Li
mesh_terms: D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D000818:Animals; D000936:Antigen-Antibody Complex / Q000097:blood / Q000187:drug effects; D001327:Autoimmune Diseases / Q000139:chemically induced / Q000276:immunology / Q000517:prevention & control*; D004231:Diuresis / Q000187:drug effects; D016061:Enterosorption; D004852:Epoxy Compounds / Q000009:adverse effects*; D005260:Female; D005921:Glomerulonephritis / Q000139:chemically induced / Q000276:immunology / Q000517:prevention & control*; D006168:Guinea Pigs; D007136:Immunoglobulins / Q000097:blood / Q000187:drug effects; D013997:Time Factors
chemical_list: D000395:Air Pollutants, Occupational; D000936:Antigen-Antibody Complex; D004852:Epoxy Compounds; D007136:Immunoglobulins