title: Structure-activity relationship studies of dynorphin A and related peptides.
abstract: An up-to-date review is presented covering all the available information concerning the isolation, discovery, synthesis, conformation, receptor binding characteristics, pharmacological properties and SAR studies of dynorphin A and related peptides. The potential of dynorphin A and its analogs has yet to be fully realized.
authors.affiliation: Division of Biopolymers, Central Drug Research Institute, Lucknow, India.
authors.forename: T
authors.initials: T
authors.lastname: Naqvi
authors.forename: W
authors.initials: W
authors.lastname: Haq
authors.forename: K B
authors.initials: KB
authors.lastname: Mathur
mesh_terms: D000698:Analgesia; D000818:Animals; D002319:Cardiovascular System / Q000187:drug effects; D004399:Dynorphins / Q000737:chemistry / Q000302:isolation & purification / Q000378:metabolism / Q000494:pharmacology; D006801:Humans; D007107:Immune System / Q000187:drug effects; D017473:Receptors, Opioid, kappa / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D017473:Receptors, Opioid, kappa; D004399:Dynorphins