[The viral genome status studied under the conditions of a mixed infection in lymphoblastoid cells by adenovirus and the Epstein-Barr virus].
Some indices have been studied which characterized the state of Epstein-Barr virus genome and adenovirus in the implanted lines of lymphoblastoid cells of B and T phenotype under the mixed or monoinfection. It has been shown that super infection by type 2 adenovirus rather sharply affects the state of Epstein-Barr virus genome in the Raji cells containing integrated Epstein-Barr virus genome. The state of adenovirus genome in the studied cells is less subject to changes. Its early area is revealed by hybridization using DNA-DNA method in a form of two fragments of different intensity which is maximum in the Raji and Jurkat cells, which evidences for the more expressivity of adenovirus genome in these cells.
Nosach
L N
LN
Diachenko
N S
NS
Povnitsa
O Iu
OIu
Smirnova
I A
IA
Kishinskaia
E G
EG
Butenko
Z A
ZA
Panasenko
G V
GV
D000258:Adenovirus Infections, Human / Q000235:genetics* / Q000821:virology; D000260:Adenoviruses, Human / Q000235:genetics*; D000818:Animals; D001402:B-Lymphocytes / Q000821:virology*; D002144:Callithrix; D002460:Cell Line; D002478:Cells, Cultured; D004279:DNA, Viral / Q000235:genetics; D016679:Genome, Viral; D006566:Herpesviridae Infections / Q000235:genetics* / Q000821:virology; D004854:Herpesvirus 4, Human / Q000235:genetics*; D006801:Humans; D009693:Nucleic Acid Hybridization / Q000379:methods; D016133:Polymerase Chain Reaction / Q000379:methods; D013601:T-Lymphocytes / Q000821:virology*; D014412:Tumor Virus Infections / Q000235:genetics* / Q000821:virology; D014776:Virus Cultivation
D004279:DNA, Viral