[The frequency of detection of and criteria for primary multiple malignant tumors in patients with mammary gland cancer].
The method of calculation of the primarily-multiple malignant tumors (PMMT) frequency depending on their occurrence succession was supposed. The frequency of synchronous PMMT calculated in relation to total quantity of patients with mammarial gland cancer (MGC) was 1.5%. The frequency of metachronous PMMT was calculated basing on the MGC patients quantity in every year of observation. The summary frequency of metachronous PMMT for last 20 years of observation of 11512 MGC patients was 16.2%, the total PMMT frequency-17.7%, approximating to the true frequency at the end of life in all the MGC patients. The differences of metachronous PMMT revealing were established, witnessing the existence of at least two heterogenic groups of patients, in one of which the influence of some etiological factors with the determined term of the cancerogenic effect realization, causing the PMMT occurrence frequency rising were established.
Sorkin
V M
VM
Efetov
V M
VM
Tel'kieva
G N
GN
D000818:Animals; D001943:Breast Neoplasms / Q000453:epidemiology* / Q000601:surgery*; D005260:Female; D006801:Humans; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology* / Q000601:surgery*; D012189:Retrospective Studies; D013997:Time Factors