title: Crack cocaine and schizophrenia as risk factors for PPD reactivity in the dually diagnosed.
abstract: We studied factors contributing to an increased risk of PPD positive status among 147 inpatients dually diagnosed for mental illness and substance abuse in a large urban hospital. Ninety-three percent (N = 137) were tested for PPD on admission. The rate of positive PPDs was 30.7%. Significant correlates of PPD positive status were the diagnosis of schizophrenia/psychosis NOS (p < .05), and crack cocaine use in the 30 days prior to admission (p < .01). A multiple logistic regression revealed a relative risk of 3.53 (p < .005) for PPD positive status for the crack using group and a relative risk of 2.16 (p < .06) for PPD positive status for the schizophrenic group. Reasons for why patients whose primary drug of abuse is crack cocaine and those whose diagnosis is schizophrenia/psychosis NOS may be at an increased risk for exposure to tuberculosis are discussed as are the implications for public health.
authors.affiliation: Department of Psychiatry, New York University Medical Center/Bellevue Hospital Center, NY, USA.
authors.forename: T
authors.initials: T
authors.lastname: Taubes
authors.forename: M
authors.initials: M
authors.lastname: Galanter
authors.forename: H
authors.initials: H
authors.lastname: Dermatis
authors.forename: L
authors.initials: L
authors.lastname: Westreich
mesh_terms: D000293:Adolescent; D000328:Adult; D019970:Cocaine-Related Disorders / Q000175:diagnosis* / Q000453:epidemiology; D015897:Comorbidity; D016578:Crack Cocaine; D017831:Diagnosis, Dual (Psychiatry); D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009519:New York City / Q000453:epidemiology; D012306:Risk; D012307:Risk Factors; D012559:Schizophrenia / Q000175:diagnosis* / Q000453:epidemiology; D014374:Tuberculin Test / Q000706:statistics & numerical data*; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000635:transmission; D014505:Urban Population / Q000706:statistics & numerical data
chemical_list: D016578:Crack Cocaine