[Clinical and experimental study for allergic rhinitis with treatment of biminkang mixture].
OBJECTIVE
To observe the efficacy of Biminkang in treating allergic rhinitis.


METHODS
One hundred and sixty-four cases of allergic rhinitis were treated with the Chinese medicine Biminkang mixture mainly consisted of the Kazak folk herb Artemisia rupestis L. and in 52 cases of allergic rhinitis were treated as the control with the patent medicine Biyankang.


RESULTS
The total effective rates in both groups are 93.9% and 69.2% respectively. After stopping the medications, the recurrence rates were 46.8% and 87.1%. Biminkang was better than Biyankang in short or long term of effectiveness (P < 0.01). Pharmacological study demonstrated Biminkang played a significant role of resisting histamine, inhibiting allergic reaction I and stabilizing cell membrane of mastocyte.


CONCLUSIONS
Biminkang mixture is an effective drug in treating allergic rhinitis.
Bao
L
L
Urumqi General Hospital of Lanzhou Military Region.
Sun
Q W
QW
Hu
L
L
D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D018926:Anti-Allergic Agents / Q000627:therapeutic use; D019306:Artemisia / Q000627:therapeutic use; D015549:Basophil Degranulation Test; D002648:Child; D002744:Chlorpheniramine / Q000627:therapeutic use; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006168:Guinea Pigs; D006801:Humans; D008297:Male; D008407:Mast Cells / Q000187:drug effects; D008875:Middle Aged; D008517:Phytotherapy; D010946:Plants, Medicinal; D051381:Rats; D017208:Rats, Wistar; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy*
D018926:Anti-Allergic Agents; D004365:Drugs, Chinese Herbal; D002744:Chlorpheniramine