Evolving views of protein glycosylation.
The composition, biosynthesis and known roles of oligosaccharides that are attached to glycoproteins suggest that multiple forces have driven the evolution of proteins that create and recognize these structures. The evolution of glycoprotein biosynthesis and recognition mechanisms can be best understood as a sequential development of functions associated with oligosaccharides.
Drickamer
K
K
Dept of Biochemistry, University of Oxford, UK. kd@glycob.ox.ac.uk
Taylor
M E
ME
D000818:Animals; D002240:Carbohydrate Sequence; D019143:Evolution, Molecular; D006023:Glycoproteins / Q000737:chemistry / Q000378:metabolism*; D006031:Glycosylation; D008969:Molecular Sequence Data; D009844:Oligosaccharides / Q000737:chemistry / Q000378:metabolism
D006023:Glycoproteins; D009844:Oligosaccharides