[A little known cause of chronic renal insufficiency in the adult: systemic tuberous sclerosis].
BACKGROUND
Angiomyolipomas and renal cysts are commonly observed in patients with systemic tuberous sclerosis. Hemorrhagic complications related to the angiomyolipomas are well known.


METHODS
A 63-year old woman was hospitalized for severe chronic renal failure. Physical examination revealed skin manifestations of systemic tuberous sclerosis, which the patient had hidden to date. The radiographic work-up demonstrated complete disorganization of the renal parenchyma in both kidneys due to multiple cysts and angiomyolipomas.


CONCLUSIONS
Chronic renal failure can be the inaugural manifestation in low-grade cases of systemic tuberous sclerosis which may go undiagnosed for years allowing progressive destruction of the kidneys.
Poux
J M
JM
Service de Néphrologie, Centre Hospitalier Général, Ajaccio.
Tifoura
A
A
Leroux-Robert
C
C
D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000209:etiology*; D008875:Middle Aged; D014402:Tuberous Sclerosis / Q000150:complications*