In vitro drug assays and statistical analysis.
The development of in vitro drug tests to assess the efficacy of drugs against Pneumocystis carinii has been hindered by the lack of efficient methods for continuous cultivation of the microorganism. However, different short-term culture systems have been proposed by many teams. In the present contribution an in vitro microplate drug assay and two statistical programs allowing the analysis of results are presented.
Atzori
C
C
II Dept. Infect. Diseases, Sacco Hospital, Milan, Italy.
Angeli
E
E
Agostoni
F
F
Mainini
A
A
Filippini
M
M
Cargnel
A
A
D000465:Algorithms; D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology*; D006801:Humans; D008432:Mathematical Computing; D008826:Microbial Sensitivity Tests / Q000379:methods*; D011010:Pneumocystis / Q000187:drug effects*
D000935:Antifungal Agents