[Chronic, infantile, neurologic, cutaneous and articular syndrome (CINCA) in an infant].
BACKGROUND
CINCA syndrome is a clinical syndrome of unclear etiology, characterized by a chronic multi-organ inflammatory process unsusceptible to treatment.


METHODS
An 18-month-old boy was admitted because he suffered, since the age of 2 months, from cutaneous, articular and neurological changes, lymphadenopathy, hepatosplenomegaly, choroiditis and psychosomatic development retardation. These clinical symptoms were unsusceptible to anti-inflammatory and antihistaminic drugs. Rehabilitation was not effective either.


CONCLUSIONS
A long-term clinical observation is required before sustained multi-organ changes beginning in early childhood and exclusion of other chronic inflammatory diseases enable the diagnosis of CINCA syndrome.
Milewska-Bobula
B
B
Clinique du nourrisson, institut Monument, centre de santé de l'enfant, Varsovie, Pologne.
Lipka
B
B
Rowecka-Trzebicka
K
K
Rostropowicz-Denisiewicz
K
K
Romicka
A
A
Witwicki
J M
JM
D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007592:Joint Diseases / Q000175:diagnosis*; D008297:Male; D009422:Nervous System Diseases / Q000175:diagnosis*; D012871:Skin Diseases / Q000175:diagnosis*; D013577:Syndrome
D000893:Anti-Inflammatory Agents; D006634:Histamine H1 Antagonists