Cell death precedes rod neurogenesis in embryonic teleost retinal development.
We measured cell death in the retinas of embryonic and adult teleost fish using TUNEL staining. Following a wave of cell birth during embryogenesis that generates all retinal cell types except rods, cell death occurs in all three nuclear layers. The lack of a corresponding pattern of cell death in the growing adult margin suggests different roles for death during embryogenesis and adult neurogenesis.
Hoke
K L
KL
Program in Neuroscience, Jordan Hall, Building 420, Stanford University, Stanford, CA 94305, USA.
Fernald
R D
RD
D000818:Animals; D016923:Cell Death / Q000502:physiology; D002454:Cell Differentiation / Q000502:physiology; D004625:Embryo, Nonmammalian / Q000166:cytology / Q000502:physiology; D010471:Perches / Q000196:embryology*; D012160:Retina / Q000166:cytology / Q000196:embryology* / Q000502:physiology; D017948:Retinal Rod Photoreceptor Cells / Q000166:cytology / Q000196:embryology* / Q000502:physiology