title: The human serotonin-7 receptor pseudogene: variation and chromosome location.
abstract: We report a variation of the pseudogene for the serotonin-7 receptor in human DNA. Human genomic DNA was amplified, using the polymerase chain reaction method and degenerate oligonucleotide primers for serotonin receptor-like genes. A novel gene DNA sequence of 1325 bp was found. Based on nucleotides, this gene is 88% identical to the serotonin-7 receptor coding sequence. Compared with the previously known serotonin-7 receptor pseudogene, this pseudogene has 1 nucleotide deletion and 4 nucleotide mutations. The gene is located on human chromosome 12 at 12p12.3-p13.2.
authors.affiliation: Department of Pharmacology, Faculty of Medicine, University of Toronto, Ont.
authors.forename: D
authors.initials: D
authors.lastname: Nam
authors.forename: I H
authors.initials: IH
authors.lastname: Qian
authors.forename: I
authors.initials: I
authors.lastname: Kusumi
authors.forename: C
authors.initials: C
authors.lastname: Ulpian
authors.forename: T
authors.initials: T
authors.lastname: Tallerico
authors.forename: I S
authors.initials: IS
authors.lastname: Liu
authors.forename: P
authors.initials: P
authors.lastname: Seeman
mesh_terms: D002875:Chromosomes / Q000235:genetics / Q000648:ultrastructure*; D002881:Chromosomes, Human, Pair 12 / Q000235:genetics / Q000648:ultrastructure; D004247:DNA / Q000235:genetics; D006801:Humans; D011985:Receptors, Serotonin / Q000235:genetics*
chemical_list: D011985:Receptors, Serotonin; C104425:serotonin 7 receptor; D004247:DNA