[The effect of a combined transplant on reparative osteogenesis in experimental bone defects of the jaw (the immediate results)].
A combined transplant consisting of bone flour plus the sorption-antimicrobial complex polymethylsiloxane + furazolidone + metronidazole is proposed to be grafted into the bone periodontal pockets in patients with generalized parodontitis. Effects were studied of the above transplant on the experimental defects of the lower jaw--of albino rats (n = 36). Morphologic changes in the immediate periods of follow-up (at day 7, 14, and 21) were characterized by a poorly manifest and short-term reactive inflammatory process in the paratransplant tissues as well as by an earlier development of the osteoid tissue and early formation of the bone regenerate.
Borysenko
A V
AV
Nesin
O F
OF
Piechkovs'kyĭ
K Ie
KIe
D000818:Animals; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D016025:Bone Transplantation / Q000379:methods*; D003131:Combined Modality Therapy; D004337:Drug Carriers; D005664:Furazolidone / Q000627:therapeutic use*; D008334:Mandible / Q000473:pathology / Q000601:surgery; D008336:Mandibular Diseases / Q000473:pathology / Q000601:surgery*; D008795:Metronidazole / Q000627:therapeutic use*; D010012:Osteogenesis; D010514:Periodontal Pocket / Q000473:pathology / Q000601:surgery; D010518:Periodontitis / Q000473:pathology / Q000601:surgery; D051381:Rats; D012828:Silicones / Q000627:therapeutic use; D013997:Time Factors
D000890:Anti-Infective Agents; D004337:Drug Carriers; D012828:Silicones; C078211:polymethylsiloxane; D008795:Metronidazole; D005664:Furazolidone