[Secondary mitochondrial diseases].
OBJECTIVE
To analyze the secondary mitochondriopathies, which are processes characterized by the presence of structural and/or functional abnormalities of mitochondria whose causes may be assumed to be situated outside these organella.


METHODS
These processes will be categorized in the following groups; 1. Specific deficiency of a intermediate metabolite or cofactor; 2. Endocrinopathies; 3. Ischemia-reperfusion; 4. Sepsis; 5. Toxins; 6. Drugs; 7. Mitochondrial respiratory chain deficiency; 8. Ageing, and 9. Oncogenesis and apoptosis.


CONCLUSIONS
The better understanding of secondary mitochondriopathies may allow to eliminate the cause of them and sometimes to establish the appropriate treatment.
Cardellach
F
F
Servicio de Medicina Interna General, Hospital Clinic, Universidad de Barcelona, España. cardell@medicina.ub.es
Casademont
J
J
Urbano-Márquez
A
A
D004579:Electron Transport / Q000502:physiology; D006801:Humans; D017240:Mitochondrial Myopathies / Q000175:diagnosis / Q000209:etiology*; D009097:Multienzyme Complexes / Q000378:metabolism
D009097:Multienzyme Complexes