Fulminant hepatic failure secondary to herpes simplex virus infection in a neonate: A case report of successful treatment with liver transplantation and perioperative acyclovir.
Neonatal disseminated herpes simplex virus (HSV) infection, including fulminant hepatic failure (FHF), is lethal, and the patients rarely have a chance for liver transplantation because of the rapid development of the disease. We describe of a case of FHF secondary to HSV infection in a neonate successfully treated by aggressive intensive care followed by liver transplantation.
Egawa
H
H
Department of Transplant Surgery, Kyoto University Hospital, Kyoto, Japan.
Inomata
Y
Y
Nakayama
S
S
Matsui
A
A
Yamabe
H
H
Uemoto
S
S
Asonuma
K
K
Tanaka
K
K
D000212:Acyclovir / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000627:therapeutic use*; D003586:Cytomegalovirus Infections / Q000150:complications / Q000188:drug therapy; D005260:Female; D006501:Hepatic Encephalopathy / Q000209:etiology* / Q000601:surgery*; D006561:Herpes Simplex / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D007231:Infant, Newborn; D016031:Liver Transplantation; D016133:Polymerase Chain Reaction
D000998:Antiviral Agents; D000212:Acyclovir