A spherical dose model for radiosurgery plan optimization.
Conventional 3D dose calculations for stereotactic radiosurgery involve integration of individual static beams comprising a set of arcs. For iterative optimization of multiple isocentre treatment, which requires repetitive dose calculations at a large number of sample points, the conventional method is too slow. To overcome this problem spherically symmetric dose distributions are assumed. The authors describe a spherical dose model derived from a parametrized convolution of the collimator width and a dose spread kernel. The method is fast and easy to implement requiring just a single empirically derived value. Furthermore, the model is differentiable with respect to the parameters to be optimized. This property is useful when the optimization strategies rely on gradient information.
Cho
P S
PS
Department of Radiation Oncology, University of Washington, Seattle 98195-6043, USA.
Kuterdem
H G
HG
Marks
R J
RJ
D008962:Models, Theoretical; D011874:Radiometry; D016634:Radiosurgery; D013238:Stereotaxic Techniques