title: Chromosome 17-linked dementias.
abstract: Chromosome 17-linked dementias have been defined by linkage analysis. The most common of these syndromes has been estimated to be the cause of between 2 and 20% of all dementia and has alternately been called frontotemporal dementia, Pick's disease (without Pick bodies) and dementia lacking distinctive features [1-3]. The identification of the mutation responsible for these conditions in a group of clinically and pathologically heterogeneous disorders may allow us to gain broad insight into the processes of neurodegeneration.
authors.affiliation: Department of Neurology, University of California, San Francisco, USA. kirk@wildtype.ucsf.edu
authors.forename: K C
authors.initials: KC
authors.lastname: Wilhelmsen
mesh_terms: D002874:Chromosome Mapping; D002886:Chromosomes, Human, Pair 17 / Q000235:genetics*; D003704:Dementia / Q000453:epidemiology / Q000235:genetics* / Q000473:pathology; D008040:Genetic Linkage; D006801:Humans; D009154:Mutation; D009410:Nerve Degeneration / Q000235:genetics; D013577:Syndrome; D016875:tau Proteins / Q000235:genetics
chemical_list: D016875:tau Proteins