title: Collagenous spherulosis: an ultrastructural study.
abstract: Ultrastructural findings are described in two cases of collagenous spherulosis associated with intraductal hyperplasia and sclerosing adenosis. The spherules showed a variable composition of basement membrane, banded collagen, and mineral deposition. Some spherules were connected to the periacinal stroma by a thin pedicle. The authors propose that spherules represent a peculiar form of stromal invagination that could be seen in a variety of breast lesions, rather than a form of intraductal hyperplasia.
authors.affiliation: Department of Pathology, University of Tennessee, Memphis, USA.
authors.forename: H M
authors.initials: HM
authors.lastname: Maluf
authors.forename: F C
authors.initials: FC
authors.lastname: Koerner
authors.forename: G R
authors.initials: GR
authors.lastname: Dickersin
mesh_terms: D001940:Breast / Q000648:ultrastructure*; D001941:Breast Diseases / Q000473:pathology*; D003094:Collagen / Q000648:ultrastructure*; D005260:Female; D006801:Humans; D008854:Microscopy, Electron; D008875:Middle Aged
chemical_list: D003094:Collagen