[Electron microscopy of the nervous apparatus of the heart sinoauricular zone in patients with idiopathic syndrome of long Q-T interval].
All nerve components of the sinus node (SN), adjacent working myocardium and nervous ganglions of 12 patients, from 9 to 50 years old, with an idiopathic syndrome of a long Q-T interval were studied electron-microscopically. Quantitative evaluation of the myocardium innervation density in this heart region was performed. Destructive changes of the myelinated and non-myelinated nervous fibers and gliocytes in the conductive myocardium of SN and working myocardium as well as in the neurocytes of the adjacent nervous ganglions were observed. Possible causes of the ultrastructural pathology in the heart sinoauricular region are discussed.
Pavlovich
E R
ER
A. L. Myasnikov Institute of Clinical Cardiology, Moscow.
D000293:Adolescent; D000328:Adult; D001283:Atrioventricular Node / Q000648:ultrastructure*; D002648:Child; D005260:Female; D005725:Ganglia, Autonomic / Q000648:ultrastructure; D006321:Heart / Q000294:innervation*; D006801:Humans; D008133:Long QT Syndrome / Q000473:pathology* / Q000503:physiopathology / Q000601:surgery; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology* / Q000648:ultrastructure; D009412:Nerve Fibers / Q000648:ultrastructure