[Gamete interactions: which sperm ligands for the oocyte membrane?].
Fertilization includes sperm-oocyte recognition, adhesion, binding, fusion and egg activation. Integrin receptors which are adhesion molecules are expressed on unfertilized oocytes. By comparing to several cell-cell interactions such as lymphocyte activation, viral fusion, bacterial infection or macrophage phagocytosis, potential sperm ligands have been identified.
Fénichel
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Groupe de Recherche sur l'Interaction gamétique, CJF-INSERM 95-04, Faculté de Médecine, Nice.
D051722:ADAM Proteins; D020101:Acrosome Reaction / Q000502:physiology; D015703:Antigens, CD / Q000502:physiology; D018957:CD59 Antigens / Q000502:physiology; D004527:Egg Proteins / Q000032:analysis; D005260:Female; D000072196:Fertilins; D006801:Humans; D008297:Male; D051916:Membrane Cofactor Protein; D008562:Membrane Glycoproteins / Q000032:analysis / Q000502:physiology; D008666:Metalloendopeptidases / Q000502:physiology; D011956:Receptors, Cell Surface; D013084:Sperm-Ovum Interactions / Q000502:physiology*; D000072216:Zona Pellucida Glycoproteins
D015703:Antigens, CD; C497857:CD46 protein, human; D018957:CD59 Antigens; D004527:Egg Proteins; D051916:Membrane Cofactor Protein; D008562:Membrane Glycoproteins; D011956:Receptors, Cell Surface; D000072216:Zona Pellucida Glycoproteins; D051722:ADAM Proteins; D000072196:Fertilins; D008666:Metalloendopeptidases