The human serotonin-7 receptor pseudogene: variation and chromosome location.
We report a variation of the pseudogene for the serotonin-7 receptor in human DNA. Human genomic DNA was amplified, using the polymerase chain reaction method and degenerate oligonucleotide primers for serotonin receptor-like genes. A novel gene DNA sequence of 1325 bp was found. Based on nucleotides, this gene is 88% identical to the serotonin-7 receptor coding sequence. Compared with the previously known serotonin-7 receptor pseudogene, this pseudogene has 1 nucleotide deletion and 4 nucleotide mutations. The gene is located on human chromosome 12 at 12p12.3-p13.2.
Nam
D
D
Department of Pharmacology, Faculty of Medicine, University of Toronto, Ont.
Qian
I H
IH
Kusumi
I
I
Ulpian
C
C
Tallerico
T
T
Liu
I S
IS
Seeman
P
P
D002875:Chromosomes / Q000235:genetics / Q000648:ultrastructure*; D002881:Chromosomes, Human, Pair 12 / Q000235:genetics / Q000648:ultrastructure; D004247:DNA / Q000235:genetics; D006801:Humans; D011985:Receptors, Serotonin / Q000235:genetics*
D011985:Receptors, Serotonin; C104425:serotonin 7 receptor; D004247:DNA