title: Treatment of peri-implant defects with guided bone regeneration: a comparative clinical study with various membranes and bone grafts.
abstract: In this clinical study, a bioabsorbable membrane (Biofix) and two augmentation membranes made of expanded polytetrafluoroethylene (Gore-Tex) were tested for their osteopromotive potential. Forty-six implants were augmented with Gore-Tex membranes, 45 implants with titanium-reinforced Gore-Tex membranes, and 38 peri-implant defects with a resorbable polyglycolid membrane (Biofix). Autogenous bone (n = 85) and bovine bone matrix (Bio-Oss, n = 16) were used as filling materials beneath membranes. The results showed that bone repair is significantly improved by the use of membrane techniques. The average rate of bone regeneration with non-resorbable membranes was 84% (GTAM) and 81% (TR-GTAM). The use of Biofix membranes resulted in an average bone gain of 60%. The differences in efficacy established for the three types of membranes were found to be statistically significant (P < .001). Barrier membranes represent a valid technique for the treatment of peri-implant defects. Clinical and histologic results showed that Bio-Oss is an osteoconductive scaffold that promotes new bone formation.
authors.affiliation: Department of Prosthodontics, School of Dentistry, University of Graz, Austria. Martin.Lorenzoni@kfunigraz.ac.at
authors.forename: M
authors.initials: M
authors.lastname: Lorenzoni
authors.forename: C
authors.initials: C
authors.lastname: Pertl
authors.forename: C
authors.initials: C
authors.lastname: Keil
authors.forename: W A
authors.initials: WA
authors.lastname: Wegscheider
mesh_terms: D020341:Absorbable Implants; D000328:Adult; D000368:Aged; D016301:Alveolar Bone Loss / Q000209:etiology / Q000601:surgery*; D000818:Animals; D001861:Bone Regeneration; D018786:Bone Substitutes; D016025:Bone Transplantation; D002417:Cattle; D003758:Dental Implantation, Endosseous; D015921:Dental Implants / Q000009:adverse effects*; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D006801:Humans; D008567:Membranes, Artificial; D008875:Middle Aged; D008903:Minerals; D011100:Polyglycolic Acid; D011138:Polytetrafluoroethylene; D016896:Treatment Outcome
chemical_list: C077540:Bio-Oss; D018786:Bone Substitutes; D015921:Dental Implants; D008567:Membranes, Artificial; D008903:Minerals; D011100:Polyglycolic Acid; D011138:Polytetrafluoroethylene