A syntaxin-SNAP 25-VAMP complex is formed without docking of synaptic vesicles.
We show herein that syntaxin is already associated with SNAP 25 and VAMP during fast axonal transport, and in isolated synaptic vesicles, before docking of these secretory organelles at the active zones.
Morel
N
N
Laboratoire de Neurobiologie Cellulaire et Moleculaire, CNRS, Gif-sur-Yvette, France.
Taubenblatt
P
P
Synguelakis
M
M
Shiff
G
G
D000818:Animals; D001370:Axonal Transport / Q000502:physiology; D008565:Membrane Proteins / Q000378:metabolism*; D009419:Nerve Tissue Proteins / Q000378:metabolism*; D011233:Precipitin Tests; D050765:Qa-SNARE Proteins; D050683:R-SNARE Proteins; D050600:SNARE Proteins; D013572:Synaptic Vesicles / Q000378:metabolism / Q000502:physiology*; D050825:Synaptosomal-Associated Protein 25; D014101:Torpedo; D033921:Vesicular Transport Proteins
D008565:Membrane Proteins; D009419:Nerve Tissue Proteins; D050765:Qa-SNARE Proteins; D050683:R-SNARE Proteins; D050600:SNARE Proteins; D050825:Synaptosomal-Associated Protein 25; D033921:Vesicular Transport Proteins