[Uterus and diethylstilbestrol: which examinations, which antecedents for an active management? Which treatments?].
Diethylstilbestrol (DES) was widely prescribed to pregnant women from 1946 to 1977. This resulted in multiple abnormalities of the genital tract. Many studies show an increased incidence of infertility, ectopic pregnancy, spontaneous abortions and premature delivery. For women with certain abnormalities such as a construction of the upper uterine cavity, with or without a T configuration of the uterus, hysteroscopic metroplasty is feasible with good anatomic and functional results.
Aubriot
F X
FX
Groupe hospitalier Cochin, Service de Gynécologie II, Paris.
Chapron
C
C
Dubuisson
J B
JB
Hamou
J E
JE
D002273:Carcinogens / Q000009:adverse effects*; D004054:Diethylstilbestrol / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007047:Hysterosalpingography; D007247:Infertility, Female / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D009153:Mutagens / Q000009:adverse effects*; D010808:Physical Examination; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects; D014463:Ultrasonography; D014599:Uterus / Q000000981:diagnostic imaging / Q000187:drug effects*
D002273:Carcinogens; D009153:Mutagens; D004054:Diethylstilbestrol