A novel simian immunodeficiency virus (SIVdrl) pol sequence from the drill monkey, Mandrillus leucophaeus.
The drill monkey has been shown by serology and PCR to harbor a unique simian immunodeficiency virus (SIVdrl). A pol sequence, amplified from uncultured peripheral blood cells, is most closely related to the equivalent SIV sequences from the red-capped mangabey (SIVrcm), the sabaeus African green monkey (SIVagmSAB), and the chimpanzee (SIVcpz) and to the human immunodeficiency virus type 1 (HIV-1) sequence of humans. It is as yet unclear whether SIVdrl has a mosaic genome like SIVrcm and SIVagmSAB, is a member of the SIVcpz/HIV-1 lineage, or represents a novel primate lentivirus lineage.
Clewley
J P
JP
Virus Reference Division, Central Public Health Laboratory, London, United Kingdom. jclewley@hgmp.mrc.ac.uk
Lewis
J C
JC
Brown
D W
DW
Gadsby
E L
EL
D000595:Amino Acid Sequence; D000818:Animals; D001483:Base Sequence; D016664:Cercocebus / Q000821:virology; D002522:Chlorocebus aethiops / Q000821:virology; D017931:DNA Primers / Q000235:genetics; D015751:Genes, pol; D016679:Genome, Viral; D015497:HIV-1 / Q000235:genetics; D006801:Humans; D008969:Molecular Sequence Data; D009030:Mosaicism; D002679:Pan troglodytes / Q000821:virology; D010215:Papio / Q000821:virology*; D010802:Phylogeny; D017386:Sequence Homology, Amino Acid; D015302:Simian Immunodeficiency Virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D013045:Species Specificity
D017931:DNA Primers