title: De novo desmoplastic neurotropic melanoma of the lower lip: a neoplasm with ominous behavior.
abstract: Desmoplastic neurotropic melanoma represents a rare histologic variant of malignant melanoma that is characterized by a proliferation of spindle cells in a densely collagenous stroma with pronounced neurotropism. A 60-year-old man appeared for evaluation of a mass in the lower lip. The labial mucosa was intact, and the lesion had been present for 2 months. The tumor was surgically removed, and after immunohistochemical and ultrastructural analysis it was diagnosed as desmoplastic neurotropic melanoma. The tumor recurred 6 months later, with involvement of the inferior alveolar nerve.
authors.affiliation: Hospital Covadonga (HCA), University of Oviedo.
authors.forename: B
authors.initials: B
authors.lastname: Madrigal
authors.forename: M F
authors.initials: MF
authors.lastname: Fresno
authors.forename: L
authors.initials: L
authors.lastname: Junquera
authors.forename: M
authors.initials: M
authors.lastname: Veiga
authors.forename: P
authors.initials: P
authors.lastname: Ablanedo
authors.forename: A
authors.initials: A
authors.lastname: Herrero
mesh_terms: D003390:Cranial Nerve Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D006801:Humans; D007150:Immunohistochemistry; D008048:Lip Neoplasms / Q000473:pathology* / Q000648:ultrastructure; D008297:Male; D008340:Mandibular Nerve / Q000473:pathology*; D008545:Melanoma / Q000473:pathology* / Q000648:ultrastructure; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009364:Neoplasm Recurrence, Local