Porphyromonas (Bacteroides) endodontalis: its role in endodontal infections.
Porphyromonas endodontalis (formerly Bacteroides endodontalis) is a black-pigmented anaerobic Gram-negative rod which is associated with endodontal infections. It has been isolated from infected dental root canals and submucous abscesses of endodontal origin. The presence of P. endodontalis in infected dental root canals has been correlated with symptoms of an acute infection. It is occasionally found on oral mucous membranes and periodontal pockets. P. endodontalis has shown relatively low virulence in experimental monoinfections. In anaerobic mixed infections it can play an essential role. Differences in virulence between strains have been related to capsular material. On the basis of different types of capsules, three serotypes have been described. P. endodontalis is sensitive to a wide range of antibiotics, including the penicillins, the tetracyclines, and metronidazole.
van Winkelhoff
A J
AJ
Department of Oral Microbiology, Academic Center for Dentistry Amsterdam, The Netherlands.
van Steenbergen
T J
TJ
de Graaff
J
J
D016172:DNA Fingerprinting; D003788:Dental Pulp Diseases / Q000382:microbiology*; D006801:Humans; D008826:Microbial Sensitivity Tests; D010482:Periapical Abscess / Q000382:microbiology*; D017861:Porphyromonas / Q000145:classification / Q000472:pathogenicity*; D012703:Serotyping; D014774:Virulence