title: Endoscopic sinus surgery and postoperative intravenous aminoglycosides in the treatment of atrophic rhinitis.
abstract: A total of 29 atrophic rhinitis patients were treated by endoscopic sinus surgery between 1990 and 1995. After the surgery, a 7 to 10-day course of systematic aminoglycoside was administered. Two cases were excluded, due to later occurrence of nasal lymphoma in one patient and incompleteness of postoperative antibiotic therapy in the other. Among those included, atrophic rhinitis occurred in the absence of prior surgery in 24 patients, and the condition was secondary to a previous intranasal surgery in the other three patients. After a 1 to 6-year follow-up (mean: 63.4 months), seven patients were successfully managed without any characteristic symptom or sign of atrophic rhinitis. Another 18 patients felt improved. Only two patients did not have any improvement. The rate of improvement was 92.6%. Overall, one patient suffered from a left retrobulbar hematoma after operation. Exposed orbital fat was observed in the other patient. The orbital complication rate was therefore 7.4%. No other major complication occurred in this series. The bacteriologic, radiological, antroscopic, and pathologic findings are also included here. It is concluded that endoscopic sinus surgery in combination with adequate postoperative antibiotic therapy can significantly treat atrophic rhinitis.
authors.affiliation: Department of Otolaryngology, Taichung Veterans' General Hospital, Taiwan, Republic of China.
authors.forename: R S
authors.initials: RS
authors.lastname: Jiang
authors.forename: C Y
authors.initials: CY
authors.lastname: Hsu
authors.forename: C C
authors.initials: CC
authors.lastname: Chen
authors.forename: Y J
authors.initials: YJ
authors.lastname: Jan
authors.forename: J W
authors.initials: JW
authors.lastname: Jang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000617:Aminoglycosides; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D001706:Biopsy; D017024:Chemotherapy, Adjuvant; D002908:Chronic Disease; D004724:Endoscopy / Q000379:methods*; D015521:Ethmoid Sinusitis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D015523:Maxillary Sinusitis / Q000150:complications* / Q000175:diagnosis / Q000628:therapy*; D008875:Middle Aged; D011182:Postoperative Care / Q000379:methods*; D012222:Rhinitis, Atrophic / Q000382:microbiology*; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents