[Pregnancy in corrected transposition of great arteries and therapy with ACE inhibitors].
A pregnancy after Mustard repair for transposition of the great arteries and ventricular septal defect with pulmonary stenosis is reported. The 23-year-old gravida 1 was treated with ACE inhibitors up to 26 weeks of gestation until cardiac medication was changed to dihydralazine. At 28 weeks of gestation the patient developed cardiac decompensation leading to caesarean section for maternal indication at 29 weeks of gestation. The neonate did not show any congenital malformation nor anuria. The patient was moved to a normal ward six days after delivery. A cardiac follow-up examination showed no difference to the condition before pregnancy.
Wacker
J
J
Frauenklinik, Ruprecht-Karls-Universität Heidelberg. juergen-wacker@krzmail.krz.uni-heidelberg.de
Unkels
R
R
Bode
C
C
Werner
P
P
Bastert
G
G
D000328:Adult; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000008:administration & dosage* / Q000009:adverse effects; D002216:Captopril / Q000008:administration & dosage* / Q000009:adverse effects; D002585:Cesarean Section; D004078:Dihydralazine / Q000008:administration & dosage; D005260:Female; D006333:Heart Failure / Q000175:diagnosis; D006345:Heart Septal Defects, Ventricular / Q000175:diagnosis; D006801:Humans; D011183:Postoperative Complications / Q000175:diagnosis*; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000175:diagnosis*; D011256:Pregnancy Outcome; D018566:Pregnancy, High-Risk; D011666:Pulmonary Valve Stenosis / Q000175:diagnosis; D014188:Transposition of Great Vessels / Q000601:surgery*
D000806:Angiotensin-Converting Enzyme Inhibitors; D002216:Captopril; D004078:Dihydralazine