title: Focal grey matter heterotopias in monozygotic twins with developmental language disorder.
abstract: We describe 9-year-old monozygotic male twins with a developmental language disorder of the phonologic-syntactic type and learning difficulties. High-resolution MRI revealed bilateral parieto-temporal grey matter heterotopias in both twins, on the left more than on the right, and more pronounced in the more affected twin. This suggests a causal relationship between the heterotopias and the neuropsychological findings in this twin pair.
  
  
  CONCLUSIONS
  Neuronal migration defects and ensuing focal heterotopias may be causally related to developmental language disorders.
authors.affiliation: Department of Paediatrics, University of Düsseldorf, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Preis
authors.forename: V
authors.initials: V
authors.lastname: Engelbrecht
authors.forename: Y
authors.initials: Y
authors.lastname: Huang
authors.forename: H
authors.initials: H
authors.lastname: Steinmetz
mesh_terms: D002540:Cerebral Cortex / Q000473:pathology*; D002648:Child; D002828:Choristoma / Q000473:pathology*; D004200:Diseases in Twins; D006801:Humans; D007806:Language Disorders / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D010296:Parietal Lobe / Q000473:pathology; D013702:Temporal Lobe / Q000473:pathology; D014430:Twins, Monozygotic