title: The analysis of driving mode influence on energy dissipation in pneumatic artificial heart chambers.
abstract: The energy dissipated in blood or on a total artificial heart (TAH) chamber's elements directly or indirectly decreases the biological or technical safety of the TAH's work. The energetic analysis of the Polish total artificial heart (POLTAH) external work with the objective of estimating the valve and membrane roles in energy dissipation has been performed. The simulation of left and right artificial heart chamber work under physiological conditions using a self-constructed physical model of the circulatory system has been performed for the full systole percent and frequency range and for different valves. The total energy dissipated on valves equals 15-30% of the chambers' work value. Energy losses on valves are influenced by the driving mode. The usage of inappropriate systolic and diastolic times increases the value of the energy dissipated on the membrane and on valves in the overall energy balance. The absolute value of the energy dissipated on the valves increases with the increase of the cycle time and depends on the valve type. The energy dissipated on the outlet valve decreases with the frequency (if the remaining driving parameters are kept constant) and for 150 bpm is nearly 3 times lower than that for 30 bpm. The energy dissipated on the membrane equals 10-50% of the TAH's work during systole, depending on the driving parameters. The filling process is assisted by the pressure from the atrium, and a great amount of energy during the diastolic period is consumed by the start of the membrane movement. We have also estimated the influence of the driving parameters on the valves' functions, measuring the acoustic wave intensity. The conclusions drawn are of a general character; they are applicable to all membrane, pneumatically powered blood pumps.
authors.affiliation: Foundation for Development of Cardiac Surgery and Silesian Medical Academy, Zabrze, Poland.
authors.forename: Z
authors.initials: Z
authors.lastname: Nawrat
authors.forename: Z
authors.initials: Z
authors.lastname: Malota
mesh_terms: D000162:Acoustics; D000388:Air; D001769:Blood; D001794:Blood Pressure; D002302:Cardiac Output; D003971:Diastole; D004735:Energy Transfer; D004867:Equipment Design; D006351:Heart Valves; D006354:Heart, Artificial; D006801:Humans; D008567:Membranes, Artificial; D012449:Safety; D013599:Systole; D013997:Time Factors
chemical_list: D008567:Membranes, Artificial