Facilitation of chromatin dynamics by SARs.
Metaphase chromosome condensation is a dynamic process that must utilize cis elements to form and maintain the final structure. Likewise, cis elements must regulate the accessibility of chromatin domains to protein machines involved in processes such as transcription. Scaffold associated regions appear to play important roles in both of these dynamic processes.
Hart
C M
CM
Departments of Biochemistry and Molecular Biology University of Geneva 30 Quai Ernest-Ansermet, CH-1211, Geneva 4, Switzerland.
Laemmli
U K
UK
D000818:Animals; D002467:Cell Nucleus / Q000648:ultrastructure; D002843:Chromatin / Q000235:genetics / Q000502:physiology*; D004247:DNA / Q000737:chemistry* / Q000235:genetics*; D005786:Gene Expression Regulation; D008677:Metaphase; D008938:Mitosis; D009690:Nucleic Acid Conformation; D014158:Transcription, Genetic
D002843:Chromatin; D004247:DNA