title: Different therapeutic approaches and outcome in the treatment of pterygium.
abstract: OBJECTIVE
  This study was initiated to investigate the role of different therapeutic modalities in the outcome of the surgical treatment of pterygium.
  
  
  METHODS
  The results of treatment of pterygia with a variety of surgical techniques were studied in 56 eyes (49 patients) operated on at Bristol Eye Hospital during a period of five years. The surgical techniques included simple excision; bare sclera; conjunctival autograft; sliding conjunctival flap; lamellar keratoplasty and penetrating keratoplasty. Twelve eyes received additional beta irradiation in a fractionated total dose of 40 Gys.
  
  
  RESULTS
  The incidence of recurrence was 23.2% for the 43 treated primary pterygia, and 23% for the 13 recurrent pterygia. All recurrences occurred between 2.5 and 11 months postoperatively. None of the 11 cases where additional beta irradiation was used showed any recurrence or other complication within the study period. In the recurrent pterygia group, the cases treated with a combination of surgical excision and beta irradiation, showed significantly lower recurrence rate (p < 0.001) compared to those cases treated with surgical excision alone.
  
  
  CONCLUSIONS
  Beta irradiation as a complement to surgical treatment of pterygium, is successful in treating high risk cases such as reoperations, whereas for the majority of primary pterygia surgical excision alone is adequate. Additionally, follow up of one year will reveal any recurrences.
authors.affiliation: University of Bristol, Department of Ophthalmology, Bristol Eye Hospital, U.K.
authors.forename: C H
authors.initials: CH
authors.lastname: Karabatsas
authors.forename: G W
authors.initials: GW
authors.lastname: Marsh
authors.forename: A M
authors.initials: AM
authors.lastname: Cook
authors.forename: S D
authors.initials: SD
authors.lastname: Cook
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D003228:Conjunctiva / Q000528:radiation effects / Q000601:surgery* / Q000637:transplantation; D016039:Corneal Transplantation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D013508:Ophthalmologic Surgical Procedures / Q000379:methods; D011625:Pterygium / Q000532:radiotherapy / Q000601:surgery*; D018714:Radiotherapy, Adjuvant; D012008:Recurrence; D012189:Retrospective Studies; D012590:Sclera / Q000601:surgery; D013524:Surgical Flaps; D016896:Treatment Outcome