title: Prevalence and correlates of aggressive behavior in Alzheimer's disease.
abstract: The authors assessed a consecutive series of 196 patients with probable Alzheimer's disease (AD) for the presence of aggressive behavior, using a standardized neurological, neuropsychiatric, and neuropsychological battery that included both the Overt Aggression Scale and the Irritability Scale. Twelve percent of patients showed aggressive episodes (5% with verbal aggression, 7% with physical aggression) during the 4 weeks preceding the psychiatric evaluation. Physical aggression was significantly associated with more frequent delusions and more severe irritability.
authors.affiliation: Department of Neuropsychiatry, Raúl Carrea Institute of Neurological Research, Buenos Aires, Argentina. eran@fleni.org.ar
authors.forename: E
authors.initials: E
authors.lastname: Chemerinski
authors.forename: G
authors.initials: G
authors.lastname: Petracca
authors.forename: A
authors.initials: A
authors.lastname: Tesón
authors.forename: L
authors.initials: L
authors.lastname: Sabe
authors.forename: R
authors.initials: R
authors.lastname: Leiguarda
authors.forename: S E
authors.initials: SE
authors.lastname: Starkstein
mesh_terms: D000368:Aged; D000374:Aggression / Q000523:psychology*; D000544:Alzheimer Disease / Q000188:drug therapy / Q000523:psychology*; D000928:Antidepressive Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D010554:Personality Disorders / Q000523:psychology; D010556:Personality Tests; D011569:Psychiatric Status Rating Scales; D011597:Psychomotor Performance / Q000502:physiology
chemical_list: D000928:Antidepressive Agents