title: The results of trabeculectomy with and without mitomycin C in young patients.
abstract: The results of primary trabeculectomy with and without mitomycin C (MMC) were evaluated in young glaucoma patients. The patients, 15-40 years of age, were divided into two main groups and two subgroups. In group IA, primary Cairns type trabeculectomy was performed in 24 eyes of 24 patients with juvenile glaucoma; in group IB, trabeculectomy + MMC 0.4 mg/ml in 3 min was done in 20 eyes of 20 patients with juvenile glaucoma; in group IIA, primary trabeculectomy was performed in 20 eyes of 20 patients with developmental glaucoma, and in group IIB, trabeculectomy + MMC 0.4 mg/ml in 3 min was performed in 16 eyes of 16 patients with developmental glaucoma. The success rate of the surgery was 75% in group IA, 90% in group IB, 50% in group IIA, and 75% in group IIB. There was no statistically significant difference among the groups in terms of success rates of trabeculectomies (p > 0.05).
authors.affiliation: Eye Department, Ankara Hospital, Ankara, Turkey.
authors.forename: I S
authors.initials: IS
authors.lastname: Yalvac
authors.forename: A
authors.initials: A
authors.lastname: Nurözler
authors.forename: C
authors.initials: C
authors.lastname: Kahraman
authors.forename: R
authors.initials: R
authors.lastname: Kasim
authors.forename: S
authors.initials: S
authors.lastname: Duman
mesh_terms: D000293:Adolescent; D000328:Adult; D005901:Glaucoma / Q000188:drug therapy* / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D016685:Mitomycin / Q000627:therapeutic use*; D019384:Nucleic Acid Synthesis Inhibitors / Q000627:therapeutic use*; D011182:Postoperative Care; D014130:Trabeculectomy / Q000379:methods; D016896:Treatment Outcome
chemical_list: D019384:Nucleic Acid Synthesis Inhibitors; D016685:Mitomycin