title: Genetic polymorphisms of apolipoproteins A-IV, E and H in Koreans.
abstract: A South Korean population from Kongju (n = 350) was screened by isoelectric focusing and immunoblotting procedures to determine the distribution of genetic variations in 3 apolipoprotein genes including APOA-IV, APOE and APOH. Although the known APOA-IV protein polymorphism was not observed, sporadic examples of 2 putative new variants were identified. The frequencies of the APOE*2, APOE*3 and APOE*4 alleles were 0.069, 0.823 and 0.107, respectively. At the APOH structural locus 3 common alleles, APOH*1 (0.010), APOH*2 (0.913) and APOH*3 (0.073) were observed. In addition, a unique APOH allele designated APOH*3 Kongju was identified in this Korean population.
authors.affiliation: Department of Biology Education, College of Education, Kongju National University, Kongju, Republic of Korea. hskim@knu.kongju.ac.kr
authors.forename: H S
authors.initials: HS
authors.lastname: Kim
authors.forename: M I
authors.initials: MI
authors.lastname: Kamboh
mesh_terms: D000328:Adult; D001054:Apolipoproteins A / Q000235:genetics*; D001057:Apolipoproteins E / Q000235:genetics*; D005260:Female; D005787:Gene Frequency; D006023:Glycoproteins / Q000235:genetics*; D006801:Humans; D007723:Korea / Q000208:ethnology; D008297:Male; D008875:Middle Aged; D010641:Phenotype; D011110:Polymorphism, Genetic; D053482:beta 2-Glycoprotein I
chemical_list: D001054:Apolipoproteins A; D001057:Apolipoproteins E; D006023:Glycoproteins; C022205:apolipoprotein A-IV; D053482:beta 2-Glycoprotein I