title: Vancomycin resistant enterococcus in a hospital-based dialysis unit.
abstract: OBJECTIVE
  The emergence of vancomycin resistant enterococcus (VRE) poses a serious threat to the health care community. Reservoirs of VRE are thought to exist in certain high-risk patient groups who reintroduce the organism into the hospital environment. The frequent use of vancomycin in dialysis patients may place this population at higher risk of developing VRE. This article describes the development of VRE and a point prevalence study conducted in a hospital-based dialysis unit.
  
  
  METHODS
  A dialysis unit of a tertiary care center in the eastern United States was selected as the study site. Patients who agreed to participate in the study after giving informed consent were included. Of the 85 members of this target population 33 (38.8%) agreed to participate in the study. The duration of the study was 30 days.
  
  
  METHODS
  After the literature was reviewed, a point prevalence study was completed at the study site. Stool samples or rectal swabs were collected from the study participants and analyzed for the presence of VRE. A chart review of patient demographic and prior treatment information was completed in order to help identify factors that correlate to the presence of VRE.
  
  
  METHODS
  Stool or rectal swab samples were cultured on selective media and sensitivity to vancomycin was measured.
  
  
  RESULTS
  A 9.1% prevalence of VRE was detected within the study group. The number of VRE positive subjects (3) did not allow statistically significant correlation with the demographic and prior treatment data collected.
  
  
  CONCLUSIONS
  Although VRE remains a serious threat to the health care community, the prevalence of VRE within the study group does not vary markedly from rates previously reported.
authors.affiliation: Georgetown University Medical Center, Washington, DC, USA.
authors.forename: A
authors.initials: A
authors.lastname: Korff
authors.forename: E
authors.initials: E
authors.lastname: Larson
authors.forename: P
authors.initials: P
authors.lastname: Kumar
authors.forename: S
authors.initials: S
authors.lastname: Peters
authors.forename: D
authors.initials: D
authors.lastname: Jackson
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016000:Cluster Analysis; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology*; D016983:Enterococcus; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology*; D006436:Hemodialysis Units, Hospital; D006801:Humans; D017053:Infection Control; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D020713:Vancomycin Resistance