N-ethylmaliemide (NEM)-stimulated potassium transport in camel erythrocytes.
In this study N-ethylmaliemide (NME)-stimulated, ouabain-resistant potassium influx in camel erythrocytes was measured using the radioactive rubidium tracer 86Rb+. The results showed that camel erythrocytes responded to NEM pretreatment by a threefold increase in influx which was Cl- dependent. The anion dependence of K+ influx in pre-treated cells was Br- > Cl- > NO3-. The pH dependence curve for NEM-stimulated K+ influx and the combination between volume and NEM stimulation in camel erythrocytes were determined. The findings indicated that the camel erythrocytes potassium transport system has many similarities to that of other mammalian species.
Gharaibeh
N S
NS
Department of Physiology & Biochemistry, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
D000818:Animals; D002162:Camelus / Q000097:blood / Q000502:physiology*; D048429:Cell Size; D004912:Erythrocytes / Q000502:physiology*; D005033:Ethylmaleimide / Q000494:pharmacology*; D017136:Ion Transport; D011188:Potassium / Q000493:pharmacokinetics; D015221:Potassium Channels / Q000187:drug effects* / Q000502:physiology
D015221:Potassium Channels; D005033:Ethylmaleimide; D011188:Potassium