title: Independent isolates of the emerging subgroup J avian leukosis virus derive from a common ancestor.
abstract: A new subgroup of avian leukosis virus (ALV) that includes a unique env gene, designated J, was identified recently in England. Sequence analysis of prototype English isolate HPRS-103 revealed several other unique genetic characteristics of this strain and provided information that it arose by recombination between exogenous and endogenous virus sequences. In the past several years, ALV J type viruses (ALV-J) have been isolated from broiler breeder flocks in the United States. We were interested in determining the relationship between the U.S. and English isolates of ALV-J. Based on sequence data from two independently derived U.S. field isolates, we conclude that the U.S. and English isolates of ALV-J derive from a common ancestor and are not the result of independent recombination events.
authors.affiliation: Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota Medical School, Minneapolis, Minnesota 55455, USA.
authors.forename: S J
authors.initials: SJ
authors.lastname: Benson
authors.forename: B L
authors.initials: BL
authors.lastname: Ruis
authors.forename: A L
authors.initials: AL
authors.lastname: Garbers
authors.forename: A M
authors.initials: AM
authors.lastname: Fadly
authors.forename: K F
authors.initials: KF
authors.lastname: Conklin
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D001353:Avian Leukosis / Q000821:virology; D001354:Avian Leukosis Virus / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D001483:Base Sequence; D002645:Chickens; D004279:DNA, Viral / Q000235:genetics; D004739:England; D019143:Evolution, Molecular; D020440:Gene Duplication; D015752:Genes, env; D015751:Genes, pol; D008969:Molecular Sequence Data; D011995:Recombination, Genetic; D017386:Sequence Homology, Amino Acid; D012689:Sequence Homology, Nucleic Acid; D014481:United States
chemical_list: D004279:DNA, Viral