[Contrast analysis of brainstem auditory evoked potential in untreated and treated hepatolenticular degeneration patients with treatment of combining traditional Chinese and Western medicine].
OBJECTIVE
To observe the effect of combination therapy of traditional and Western medicine (TCM-WM) on brainstem auditory evoked potential (BAEP) in hepatolenticular degeneration patients.


METHODS
BAEP was recorded and analyzed in 65 patients with hepatolenticular degeneration (HLD) before and after decoppered TCM-WM treatment.


RESULTS
The peak latency (PL) and interpeak latency (IPL) of BAEP in untreated patients were greatly increased compared with those of control group, especially in the prolongations of III, V, III- V and I-V. The PL and IPL improved as improvement of clinical symptoms in HLD patients treated with TCM-WM than that in untreated patients. The abnormal rates of men and women in BAEP were decreased from 21.97% and 19.05% in untreated patients to 9.09% and 6.75% in treated patients respectively.


CONCLUSIONS
BAEP not only has an complementary diagnosis but also judge the efficacy of treatment on the HLD disease.
Xu
S H
SH
Institute of Neurology, Anhui College of TCM, Hefei.
Cai
Y L
YL
Yang
R M
RM
D000293:Adolescent; D000328:Adult; D002614:Chelating Agents / Q000627:therapeutic use; D002648:Child; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D016057:Evoked Potentials, Auditory, Brain Stem / Q000187:drug effects*; D005260:Female; D006527:Hepatolenticular Degeneration / Q000188:drug therapy / Q000503:physiopathology*; D006801:Humans; D008297:Male; D010396:Penicillamine / Q000627:therapeutic use; D004113:Succimer / Q000627:therapeutic use
D002614:Chelating Agents; D004365:Drugs, Chinese Herbal; D004113:Succimer; D010396:Penicillamine