title: Comment on the cylindrical capacitor electrospray interface.
abstract: Wang and Hackett have recently proposed (Anal. Chem. 1998, 70, 205-212) a new electrospray interface described as a "concentric cylindrical capacitor". Excellent spectra were obtained, especially in the negative ion mode, with lipid A, a 15-mer oligonucleotide, and a series of proteins. We find that similar results can be obtained merely by ensuring a direct electrical contact between the analyte inside a fused-silica capillary and the high-voltage supply. No capacitor effect need be invoked.
authors.forename: S
authors.initials: S
authors.lastname: König
authors.forename: H M
authors.initials: HM
authors.lastname: Fales
authors.forename: K D
authors.initials: KD
authors.lastname: Haegele
mesh_terms: D008050:Lipid A / Q000737:chemistry; D013058:Mass Spectrometry / Q000295:instrumentation*; D009841:Oligonucleotides / Q000737:chemistry; D011506:Proteins / Q000737:chemistry; D012822:Silicon Dioxide
chemical_list: D008050:Lipid A; D009841:Oligonucleotides; D011506:Proteins; D012822:Silicon Dioxide