title: [Preventive effects of tetrandrine on pulmonary hypertension and right ventricular hypertrophy in rats induced by monocrotaline].
abstract: Pulmonary hypertension and right ventricular hypertrophy in rats were developed 3 weeks after administration of monocrotaline 50 mg/kg i.p. Tetrandrine 10 mg/kg and 15 mg/kg bid p.o. could prevent the above-said effects produced by monocrotaline.
authors.affiliation: Pharmacology Department, China Medical University, Shenyang.
authors.forename: X
authors.initials: X
authors.lastname: Jin
authors.forename: X
authors.initials: X
authors.lastname: Zhang
authors.forename: J
authors.initials: J
authors.lastname: Xing
authors.forename: K
authors.initials: K
authors.lastname: Liu
authors.forename: H
authors.initials: H
authors.lastname: Wang
mesh_terms: D000470:Alkaloids / Q000627:therapeutic use*; D000818:Animals; D044182:Benzylisoquinolines; D001794:Blood Pressure / Q000187:drug effects; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D006976:Hypertension, Pulmonary / Q000139:chemically induced / Q000517:prevention & control*; D017380:Hypertrophy, Right Ventricular / Q000139:chemically induced / Q000517:prevention & control*; D008297:Male; D016686:Monocrotaline; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000470:Alkaloids; D044182:Benzylisoquinolines; D002121:Calcium Channel Blockers; C009438:tetrandrine; D016686:Monocrotaline