title: SPECT electronic collimation resolution enhancement using chi-square minimization.
abstract: An electronic collimation technique is developed which utilizes the chi-square goodness-of-fit measure to filter scattered gammas incident upon a medical imaging detector. In this data mining technique, Compton kinematic expressions are used as the chi-square fitting templates for measured energy-deposition data involving multiple-interaction scatter sequences. Fit optimization is conducted using the Davidon variable metric minimization algorithm to simultaneously determine the best-fit gamma scatter angles and their associated uncertainties, with the uncertainty associated with the first scatter angle corresponding to the angular resolution precision for the source. The methodology requires no knowledge of materials and geometry. This pattern recognition application enhances the ability to select those gammas that will provide the best resolution for input to reconstruction software. Illustrative computational results are presented for a conceptual truncated-ellipsoid polystyrene position-sensitive fibre head-detector Monte Carlo model using a triple Compton scatter gamma sequence assessment for a 99mTc point source. A filtration rate of 94.3% is obtained, resulting in an estimated sensitivity approximately three orders of magnitude greater than a high-resolution mechanically collimated device. The technique improves the nominal single-scatter angular resolution by up to approximately 24 per cent as compared with the conventional analytic electronic collimation measure.
authors.affiliation: Department of Radiology, The University of Texas, Southwestern Medical Center at Dallas, 75235, USA.
authors.forename: J W
authors.initials: JW
authors.lastname: Durkee
authors.forename: P P
authors.initials: PP
authors.lastname: Antich
authors.forename: E N
authors.initials: EN
authors.lastname: Tsyganov
authors.forename: A
authors.initials: A
authors.lastname: Constantinescu
authors.forename: J L
authors.initials: JL
authors.lastname: Fernando
authors.forename: P V
authors.initials: PV
authors.lastname: Kulkarni
authors.forename: B J
authors.initials: BJ
authors.lastname: Smith
authors.forename: G M
authors.initials: GM
authors.lastname: Arbique
authors.forename: M A
authors.initials: MA
authors.lastname: Lewis
authors.forename: T
authors.initials: T
authors.lastname: Nguyen
authors.forename: A
authors.initials: A
authors.lastname: Raheja
authors.forename: G
authors.initials: G
authors.lastname: Thambi
authors.forename: R W
authors.initials: RW
authors.lastname: Parkey
mesh_terms: D000465:Algorithms; D016009:Chi-Square Distribution; D003198:Computer Simulation; D003952:Diagnostic Imaging / Q000379:methods* / Q000706:statistics & numerical data; D005720:Gamma Rays; D012542:Scattering, Radiation; D012984:Software; D014054:Tomography; D015899:Tomography, Emission-Computed, Single-Photon / Q000379:methods* / Q000706:statistics & numerical data