Chromatin structure: linking structure to function with histone H1.
A recent study has determined the position and orientation in the nucleosome of the H1 variant 'linker histone' H5; the results focus attention on the unknown function of this highly abundant nuclear protein, and highlight the question of whether H1 is primarily an architectural or a gene-regulatory protein.
Widom
J
J
Department of Biochemistry, Northwestern University, Evanston, Illinois 60208-3500, USA. j-widom@nwu.edu
D000818:Animals; D002843:Chromatin / Q000737:chemistry* / Q000502:physiology; D004247:DNA / Q000737:chemistry* / Q000378:metabolism; D006657:Histones / Q000737:chemistry* / Q000235:genetics / Q000378:metabolism; D009690:Nucleic Acid Conformation; D009707:Nucleosomes / Q000378:metabolism; D011487:Protein Conformation
D002843:Chromatin; D006657:Histones; D009707:Nucleosomes; D004247:DNA