title: The effects of early and sustained intervention on the long-term morbidity of schizophrenia.
abstract: By examining the literature concerning early intervention with antipsychotic medications, and how it affects long-term morbidity, this article will review the concept that early intervention with antipsychotic medications improves the long-term course of schizophrenia. It also looks at the potential long-term effects of discontinuing antipsychotic medications early in the course of schizophrenia. It appears that early intervention with antipsychotic medications decreases some of the long-term morbidity associated with schizophrenia. Some of the implications of this finding are discussed in the context of both clinical practice and clinical research.
authors.affiliation: Neuropsychiatry Branch NIMH-NIH Neuroscience Center at St Elizabeths, Washington, D.C. 20032, USA.
authors.forename: R J
authors.initials: RJ
authors.lastname: Wyatt
authors.forename: I D
authors.initials: ID
authors.lastname: Henter
mesh_terms: D014150:Antipsychotic Agents / Q000627:therapeutic use*; D018450:Disease Progression; D006801:Humans; D012559:Schizophrenia / Q000188:drug therapy*; D013997:Time Factors
chemical_list: D014150:Antipsychotic Agents