title: Are new antibiotics on the horizon?
abstract: BACKGROUND
  The development of new antimicrobials is driven by the emergence of resistant bacteria, a change in disease pattern such as that caused by opportunistic and nosocomial infections and a need for improved pharmacokinetics or reduced adverse reactions.
  
  
  OBJECTIVE
  This article looks at the emerging resistances of significance in the 1990s and then at the new antibiotics that are either to be released or are under development.
  
  
  CONCLUSIONS
  Although some of these antibiotics show great promise, their long term value will ultimately be determined by how appropriately they are used by the medical community.
authors.affiliation: Royal Perth Hospital, Western Australia.
authors.forename: K
authors.initials: K
authors.lastname: Christiansen
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D017714:Community-Acquired Infections / Q000188:drug therapy; D004352:Drug Resistance, Microbial; D015507:Drugs, Investigational; D016908:Gram-Positive Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D006801:Humans
chemical_list: D000900:Anti-Bacterial Agents; D015507:Drugs, Investigational