Herpes simplex virus type 2 DNA detected in cerebrospinal fluid of 9 patients with Mollaret's meningitis.
We present clinical and virological data on 9 patients, 7 women and 2 men aged 31-56 years, with recurrent aseptic meningitis (Mollaret's meningitis). Polymerase chain reaction detected Herpes simplex virus type 2 DNA in cerebrospinal fluid samples from all patients collected during their latest attacks of meningitis. Six patients had no history of genital herpes. Only 1 patient was offered prophylactic antiviral treatment during the study period (45 months).
Jensenius
M
M
Department of Internal Medicine, Aker University Hospital, Oslo, Norway.
Myrvang
B
B
Størvold
G
G
Bucher
A
A
Hellum
K B
KB
Bruu
A L
AL
D000328:Adult; D004279:DNA, Viral / Q000134:cerebrospinal fluid*; D005260:Female; D006558:Herpes Genitalis / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000821:virology; D018258:Herpesvirus 2, Human / Q000235:genetics*; D006801:Humans; D008297:Male; D008582:Meningitis, Aseptic / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000821:virology; D008587:Meningitis, Viral / Q000134:cerebrospinal fluid / Q000175:diagnosis / Q000821:virology; D008875:Middle Aged; D012008:Recurrence
D004279:DNA, Viral