title: The effect of exercise training on the severity and duration of a viral upper respiratory illness.
abstract: OBJECTIVE
  The purpose of this investigation was to determine whether exercise training affects the severity and duration of a rhinovirus-caused upper respiratory illness (URI).
  
  
  METHODS
  Subjects who were rhinovirus 16 (RV 16) antibody-free completed a graded exercise test. Thirty-four individuals (ages 18-29 yr) of moderate fitness (32 mL.kg-1.min-1 to 60 mL.kg-1.min-1) were randomly assigned to the exercise group (EX) while 16 additional individuals of similar age and fitness served as a nonexercise (NEX) control group. All EX and NEX subjects were inoculated with RV 16 on 2 consecutive days. EX subjects completed 40 min of supervised exercise every other day at 70% of heart rate (HR) reserve for a 10-d period. Every 12 h, all subjects completed a 13-item symptom severity checklist and a physical activity log. Used facial tissues were collected and weighed (symptom severity measure) during these same reporting periods.
  
  
  RESULTS
  A two group by nine measure (2 x 9) repeated measures ANOVA procedure showed no difference in symptom questionnaire mean scores and the mucous weights of the EX and NEX groups for days 2-10 of the experiment. A two measure by five measure (2 x 5) repeated measures ANOVA procedure indicated no differences between the pre- and post-exercise questionnaire means for the five sessions that EX subjects exercised. Statistical significance was set at P < 0.05.
  
  
  CONCLUSIONS
  These results suggest that moderate exercise training during a rhinovirus-caused URI under the conditions of this study design do not alter the severity and duration of the illness.
authors.affiliation: School of Physical Education, Ball State University, Muncie, IN 47306, USA.
authors.forename: T G
authors.initials: TG
authors.lastname: Weidner
authors.forename: T
authors.initials: T
authors.lastname: Cranston
authors.forename: T
authors.initials: T
authors.lastname: Schurr
authors.forename: L A
authors.initials: LA
authors.lastname: Kaminsky
mesh_terms: D000293:Adolescent; D000328:Adult; D000704:Analysis of Variance; D016022:Case-Control Studies; D003139:Common Cold / Q000503:physiopathology*; D015444:Exercise / Q000502:physiology*; D005260:Female; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008297:Male; D009043:Motor Activity; D009093:Mucus / Q000378:metabolism; D010809:Physical Fitness; D012141:Respiratory Tract Infections / Q000821:virology*; D012229:Rhinovirus; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D013997:Time Factors