[A pharmacokinetic study of lidocaine in patients undergoing liposuction with tumescent technique].
The purpose of this study was to evaluate the pharmacokinetics of lidocaine in the patients undergoing liposuction after subcutaneous infiltration of 0.06% lidocaine. It was found that the absorption of lidocaine was slow. The mean peak concentration of lidocaine that was 1.16 ug/mg with a range of 0.67 to 2.84 ug/mg occurred 4-13 hours after lidocaine administration. The peak concentration (Y) was correlated with the dose (X) of lidocaine, which was drawn as Y = -0.494 + 0.071X (r = 0.934, P < 0.001). We concluded that the tumescent technique is an effective and safe method for the patients undergoing liposuction.
Zhao
Y
Y
Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Beijing.
Song
Y
Y
Xue
F
F
D000328:Adult; D000779:Anesthetics, Local / Q000493:pharmacokinetics*; D005260:Female; D006801:Humans; D007279:Injections, Subcutaneous; D008012:Lidocaine / Q000493:pharmacokinetics*; D015187:Lipectomy / Q000379:methods; D008875:Middle Aged
D000779:Anesthetics, Local; D008012:Lidocaine