title: Effect of an alum-containing mouthrinse in children for plaque and salivary levels of selected oral microflora.
abstract: The purpose of the study was to assess the effect of daily supervised rinsing with a specially formulated, alum-containing mouthrinse on plaque and salivary levels of S. mutans, S. mitis and S. salivarius in caries susceptible children (12-14 years old) and to monitor the effect on the oral tissues and acceptability to subjects. Forty-five subjects were divided into 3 groups (n = 15). Group I received an experimental group with a mouthrinse containing hydrated aluminum potassium sulfate (alum). Group 2 received a vehicle control group containing the same mouthrinse, but without alum and Group 3 had a treatment control with distilled water. All subjects continued normal oral hygiene habits during the study. Salivary and plaque levels were obtained at base line, 2 weeks and 4 weeks and evaluated for microbiologic procedures. Also, potential adverse effects on oral tissues were performed during every visit. The mean plaque and salivary levels of oral Streptococcus (S. mutans, S. mitis, S. salivarius) for the experimental group were significantly reduced after 2 weeks and 4 weeks compared with baseline. The plaque and salivary levels of oral Streptococcus of experimental and vehicle control group differed statistically from each other after 4 weeks, with the strongest reduction in the experimental group and there was statistically difference between treatment control and vehicle control or experimental groups at each time interval. No evidence of deleterious effects to the oral tissues was observed. Daily use of an alum-containing mouthrinse was safe and produced significant reduction effect on plaque and salivary levels of oral Streptococcus and can be used in children for the preventive dentistry.
authors.affiliation: Gazi University, Faculty of Dentistry Department of Pedodontics, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Olmez
authors.forename: H
authors.initials: H
authors.lastname: Can
authors.forename: H
authors.initials: H
authors.lastname: Ayhan
authors.forename: H
authors.initials: H
authors.lastname: Okur
mesh_terms: D000293:Adolescent; D000534:Alum Compounds / Q000494:pharmacology* / Q000627:therapeutic use; D000704:Analysis of Variance; D002648:Child; D004245:DMF Index; D003773:Dental Plaque / Q000382:microbiology* / Q000628:therapy; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D008297:Male; D009067:Mouthwashes / Q000494:pharmacology* / Q000627:therapeutic use; D012463:Saliva / Q000382:microbiology*; D013291:Streptococcus / Q000187:drug effects* / Q000302:isolation & purification; D013295:Streptococcus mutans / Q000187:drug effects / Q000302:isolation & purification
chemical_list: D000534:Alum Compounds; D009067:Mouthwashes; C041524:aluminum sulfate