title: Successful management of stage 4S neuroblastoma and severe hepatomegaly using absorbable mesh in an infant.
abstract: This report describes the use of an absorbable mesh in an infant with stage 4S neuroblastoma who required decompressive laparotomy. At the time of laparotomy, a SILASTIC silo was placed. After 12 days, the liver had not reduced in size despite chemotherapy and radiation therapy. Because of concern for infection, the silo was removed, and an absorbable polygalactin (Vicryl) mesh was placed. Wet-to-dry dressings were used to manage the mesh. A granulation base developed that provided a physiological closure of the abdominal cavity. Forty-two days after placement of the absorbable mesh, the liver had reduced to a size that permitted mobilization of skin flaps for a surgical abdominal closure. The liver continued to reduce in size, allowing the fascial edges to draw together. The patient is now 2 years old with no signs of residual tumor or ventral hernia.
authors.affiliation: Department of Surgery, University of Virginia Health Sciences Center, Charlottesville 22908, USA.
authors.forename: E D
authors.initials: ED
authors.lastname: McGahren
authors.forename: B M
authors.initials: BM
authors.lastname: Rodgers
authors.forename: P E
authors.initials: PE
authors.lastname: Waldron
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000601:surgery*; D019299:Decompression, Surgical / Q000379:methods*; D006529:Hepatomegaly; D006801:Humans; D007231:Infant, Newborn; D008113:Liver Neoplasms / Q000601:surgery*; D008297:Male; D009447:Neuroblastoma / Q000601:surgery*; D013526:Surgical Mesh