title: FAIR excluding radiation damping (FAIRER).
abstract: It is shown that the flow-sensitive alternating inversion recovery (FAIR) technique is complicated by the effect of radiation damping, leading to problems in calibrating this method on phantoms and to inaccuracies in measured flows. A modified scheme called FAIRER (FAIR excluding radiation damping) is proposed, which suppresses the damping effects by employing very weak magnetic field gradients (0.06 G/cm) during the inversion recovery, spin-echo, and predelay periods. Results on phantoms and in vivo on cat brain are presented that demonstrate that FAIRER effectively solves these problems.
authors.affiliation: Johns Hopkins University Medical School, Department of Radiology, Baltimore, Maryland 21205-2195, USA.
authors.forename: J
authors.initials: J
authors.lastname: Zhou
authors.forename: S
authors.initials: S
authors.lastname: Mori
authors.forename: P C
authors.initials: PC
authors.lastname: van Zijl
mesh_terms: D000818:Animals; D001783:Blood Flow Velocity; D001921:Brain / Q000033:anatomy & histology / Q000098:blood supply* / Q000000981:diagnostic imaging; D002138:Calibration; D002415:Cats; D002560:Cerebrovascular Circulation; D017352:Echo-Planar Imaging / Q000295:instrumentation* / Q000379:methods*; D066298:In Vitro Techniques; D008955:Models, Cardiovascular; D019047:Phantoms, Imaging; D011877:Radionuclide Imaging; D012542:Scattering, Radiation; D012680:Sensitivity and Specificity; D013113:Spin Labels
chemical_list: D013113:Spin Labels