title: [HIV-1 proteinase mutant with an altered region of the active center].
authors.forename: N I
authors.initials: NI
authors.lastname: Dergousova
authors.forename: L D
authors.initials: LD
authors.lastname: Rumsh
authors.forename: N S
authors.initials: NS
authors.lastname: Andreeva
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D001665:Binding Sites; D002384:Catalysis; D003001:Cloning, Molecular; D017931:DNA Primers; D004591:Electrophoresis, Polyacrylamide Gel; D004926:Escherichia coli / Q000235:genetics; D016333:HIV Protease / Q000235:genetics / Q000302:isolation & purification / Q000378:metabolism*; D015497:HIV-1 / Q000201:enzymology*; D006801:Humans; D007328:Insulin / Q000378:metabolism; D008969:Molecular Sequence Data; D016297:Mutagenesis, Site-Directed; D011487:Protein Conformation; D011994:Recombinant Proteins / Q000378:metabolism
chemical_list: D017931:DNA Primers; D007328:Insulin; D011994:Recombinant Proteins; D016333:HIV Protease