A distinct Mendelian autosomal recessive syndrome involving the association of anotia, palate agenesis, bifid tongue, and polydactyly in the dog.
A presumed genetic syndrome is described in a family of St. Bernards. Four identically affected littermates presented the association of palate agenesis, anotia, incomplete bifid tongue, preaxial hind paw polydactyly, and an extra thoracic vertebra and rib. Pedigree analysis is compatible with an autosomal recessive gene.
Villagómez
D A
DA
Centro de Biotecnología Animal, Universidad de Guadalajara, México.
Alonso
R A
RA
D000818:Animals; D002869:Chromosome Aberrations / Q000662:veterinary*; D025063:Chromosome Disorders; D004283:Dog Diseases / Q000235:genetics*; D004285:Dogs; D005260:Female; D005808:Genes, Recessive; D008297:Male; D009056:Mouth Abnormalities / Q000235:genetics / Q000662:veterinary*; D010159:Palate / Q000002:abnormalities; D010375:Pedigree; D017689:Polydactyly / Q000235:genetics / Q000662:veterinary*; D014059:Tongue / Q000002:abnormalities