Vestibulocollic reflexes evoked by short-duration galvanic stimulation in man.
1. Vestibular-dependent responses in leg muscles following transmastoid galvanic stimulation have been well characterized. Here we describe the properties of vestibulocollic responses evoked by transmastoid galvanic stimulation. 2. In twelve healthy human subjects we examined the averaged responses in unrectified sternocleidomastoid (SCM) EMG evoked by transmastoid stimulation using current pulses of 4 mA intensity and 2 ms duration. In ten subjects we also examined the effects of unilateral vestibular stimulation with the indifferent electrode at the vertex. In further experiments we studied the effects of different levels of background muscle activation, head position, current intensity and current duration. We compared these responses with click-evoked vestibulocollic responses in SCM. 3. A clearly defined biphasic response, beginning with a surface positivity, was recorded in the SCM ipsilateral to the side of cathode placement in all subjects. We refer to this as the p13/n23 [g] (galvanic) response, given the close similarity, in terms of waveform and latencies, to the previously described click-evoked p13/n23 vestibulocollic response. The amplitude of this response was linearly related to background muscle activation, current intensity and current duration, but independent of head position. Unilateral galvanic stimulation revealed the p13/n23 [g] response to be solely generated by the cathode. 4. A biphasic response beginning with a surface negativity (n12/p20 [g]) contralateral to the cathode was seen in all subjects and was generated by both the cathode contralaterally and the anode ipsilaterally. 5. Both the p13/n23 [g] and n12/p20 [g] potentials were abolished by selective vestibular nerve section and unaffected by severe sensorineural deafness. 6. We conclude that galvanic stimulation evokes short-latency vestibulocollic reflexes. These vestibulocollic reflexes have properties that are distinct from those described for galvanic-evoked vestibular reflexes in leg muscles, and which may be related to their differing physiological roles.
Watson
S R
SR
Institute of Neurological Sciences, Prince of Wales Hospital, Randwick, Sydney 2031, Australia.
Colebatch
J G
JG
D000161:Acoustic Stimulation; D000328:Adult; D000368:Aged; D003638:Deafness / Q000503:physiopathology; D004558:Electric Stimulation / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009333:Neck / Q000502:physiology*; D009334:Neck Muscles / Q000502:physiology; D011184:Postoperative Period; D012018:Reflex / Q000502:physiology*; D013997:Time Factors; D014725:Vestibular Nerve / Q000601:surgery; D014722:Vestibule, Labyrinth / Q000294:innervation / Q000502:physiology* / Q000601:surgery