title: Acute myeloblastic leukemia with trilineage myelodysplasia and CD34+ blast cells with abnormal chromatin clumping.
abstract: Abnormal chromatin clumping can be observed in myelodysplastic syndromes, myeloproliferative syndromes, acute leukemias and the abnormal chromatin clumping syndrome. It occurs mainly in mature and semimature blood cells. We report a case of acute myeloid leukemia with trilineage myelodysplasia (AML/TMDS) in which there was chromatin clumping in blast cells.
authors.forename: S
authors.initials: S
authors.lastname: Gil
authors.forename: E
authors.initials: E
authors.lastname: Luño
authors.forename: J A
authors.initials: JA
authors.lastname: Rodriguez
mesh_terms: D000208:Acute Disease; D000368:Aged; D001853:Bone Marrow / Q000473:pathology*; D019070:Cell Lineage; D002843:Chromatin / Q000648:ultrastructure*; D005260:Female; D006412:Hematopoietic Stem Cells / Q000473:pathology*; D006801:Humans; D007951:Leukemia, Myeloid / Q000473:pathology*; D009190:Myelodysplastic Syndromes / Q000473:pathology*; D014411:Neoplastic Stem Cells / Q000648:ultrastructure*
chemical_list: D002843:Chromatin