Nevus with fat: clinical characteristics of 100 nevi containing mature adipose cells.
BACKGROUND
The presence of mature adipose cells among the dermal melanocytes of nevi (nevi with fat) has previously been reported. However, its clinical features are not well characterized.


OBJECTIVE
Our goal was to develop a better clinical understanding and insight into the histogenesis of nevi with fat by characterizing the patients' age, sex, height, weight, and location of lesion.


METHODS
This was a prospective study of 100 nevi with fat from 89 patients over an 18-month period.


RESULTS
Nevi with fat occur 4 times more commonly in women than men. They were diagnosed most often in patients between the ages of 40 to 49 years. The most frequent location is the head and neck. Most nevi with fat are intradermal.


CONCLUSIONS
The appearance of fat within nevi is probably a multifactorial process. Age, weight, and sun exposure may be factors associated with the occurrence of nevi with fat.
Eng
W
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Department of Pathology, University of Texas-Houston Medical School, USA.
Cohen
P R
PR
D017667:Adipocytes / Q000473:pathology*; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001827:Body Height; D001835:Body Weight; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology; D006801:Humans; D008297:Male; D008544:Melanocytes / Q000473:pathology; D008875:Middle Aged; D009506:Nevus / Q000473:pathology*; D018330:Nevus, Intradermal / Q000473:pathology; D011446:Prospective Studies; D012737:Sex Factors; D012878:Skin Neoplasms / Q000473:pathology*; D013472:Sunlight / Q000009:adverse effects