Black hair follicular dysplasia, an autosomal recessive condition in dogs.
Using histology, a coat color abnormality and the subsequent hair loss were diagnosed as black hair follicular dysplasia. A pedigree analysis of an affected litter and literature review suggests that this is inherited as an autosomal recessive trait. The melanocyte stimulating hormone receptor gene is ruled out by using linkage analysis.
Schmutz
S M
SM
Department of Animal and Poultry Science, University of Saskatchewan, Saskatoon.
Moker
J S
JS
Clark
E G
EG
Shewfelt
R
R
D000818:Animals; D002869:Chromosome Aberrations / Q000662:veterinary*; D025063:Chromosome Disorders; D004285:Dogs; D004476:Ectodermal Dysplasia / Q000235:genetics / Q000662:veterinary*; D005260:Female; D005808:Genes, Recessive; D006200:Hair Color / Q000235:genetics*; D006201:Hair Diseases / Q000235:genetics / Q000662:veterinary; D018859:Hair Follicle / Q000002:abnormalities*; D008297:Male; D010375:Pedigree