[Incidence of tumors in renal transplant patients. Is there a changing tumor pattern in these patients?].
OBJECTIVE
To analyze the incidence of tumors in renal graft recipients, the course, treatment and its effect on the graft and patient.


METHODS
We conducted a retrospective and prospective study on 477 renal transplants performed at our hospital from 1980 to 1996. The tumor type, course and possible tumor-related factors (immunosuppression, age, sex, graft rejection, virus) were analyzed.


RESULTS
57 tumors were found; 41 patients had at least one tumor. The most common were skin, renal and lung cancer. Age, sex and immunosuppression were found to be tumor-related factors in renal transplant recipients.


CONCLUSIONS
Patients undergoing renal transplantation are at a higher risk for developing a tumor, above all in the older male patients. A relationship was found for immunosuppression, the number of drugs received and the number of rejection episodes. Furthermore, the tumor pattern in these patients is different from the usual pattern.
Hermida Gutiérrez
J F
JF
Cátedra y Servicio de Urología, Servicio de Nefrología, Hospital Clínico San Carlos, Madrid, España.
Moreno Sierra
J
J
Blázquez Izquierdo
J
J
Gómez Vegas
A
A
Silmi Moyano
A
A
Prats Sánchez
D
D
Fernández Pérez
C
C
Resel Estévez
L
L
D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D006084:Graft Rejection / Q000517:prevention & control; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D015994:Incidence; D016030:Kidney Transplantation / Q000276:immunology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology* / Q000276:immunology; D011446:Prospective Studies; D012189:Retrospective Studies; D012737:Sex Factors; D013030:Spain / Q000453:epidemiology
D007166:Immunosuppressive Agents