title: Fulminant hepatic failure secondary to herpes simplex virus infection in a neonate: A case report of successful treatment with liver transplantation and perioperative acyclovir.
abstract: Neonatal disseminated herpes simplex virus (HSV) infection, including fulminant hepatic failure (FHF), is lethal, and the patients rarely have a chance for liver transplantation because of the rapid development of the disease. We describe of a case of FHF secondary to HSV infection in a neonate successfully treated by aggressive intensive care followed by liver transplantation.
authors.affiliation: Department of Transplant Surgery, Kyoto University Hospital, Kyoto, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Egawa
authors.forename: Y
authors.initials: Y
authors.lastname: Inomata
authors.forename: S
authors.initials: S
authors.lastname: Nakayama
authors.forename: A
authors.initials: A
authors.lastname: Matsui
authors.forename: H
authors.initials: H
authors.lastname: Yamabe
authors.forename: S
authors.initials: S
authors.lastname: Uemoto
authors.forename: K
authors.initials: K
authors.lastname: Asonuma
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use*; D000998:Antiviral Agents / Q000627:therapeutic use*; D003586:Cytomegalovirus Infections / Q000150:complications / Q000188:drug therapy; D005260:Female; D006501:Hepatic Encephalopathy / Q000209:etiology* / Q000601:surgery*; D006561:Herpes Simplex / Q000150:complications* / Q000188:drug therapy*; D006801:Humans; D007231:Infant, Newborn; D016031:Liver Transplantation; D016133:Polymerase Chain Reaction
chemical_list: D000998:Antiviral Agents; D000212:Acyclovir