title: Triplet pregnancy complicated by a gradual decline in antithrombin-III activity and HELLP syndrome: a case report.
abstract: We prospectively evaluated the antenatal changes in antithrombin-III (AT-III) activity and liver enzymes in a woman with a triplet pregnancy. A gradual decline in AT-III activity occurred in the absence of clinical signs of preeclampsia and preceded the onset of the typical HELLP syndrome in this patient. Monitoring of AT-III activity might help to avoid the development of severe HELLP syndrome.
authors.affiliation: Department of Obstetrics and Gynecology, Jichi Medical School, Tochigi, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Izumi
authors.forename: H
authors.initials: H
authors.lastname: Minakami
authors.forename: S
authors.initials: S
authors.lastname: Matsubara
authors.forename: I
authors.initials: I
authors.lastname: Sato
mesh_terms: D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000990:Antithrombin III / Q000378:metabolism* / Q000494:pharmacology; D002585:Cesarean Section; D005260:Female; D005307:Fertilization in Vitro; D017359:HELLP Syndrome / Q000097:blood* / Q000201:enzymology / Q000628:therapy; D006242:Haptoglobins / Q000032:analysis; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008099:Liver / Q000201:enzymology; D008297:Male; D010976:Platelet Count; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood* / Q000201:enzymology; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple / Q000097:blood / Q000378:metabolism / Q000502:physiology*; D011446:Prospective Studies; D014310:Triplets; D014527:Uric Acid / Q000097:blood
chemical_list: D006242:Haptoglobins; D014527:Uric Acid; D000990:Antithrombin III; D007770:L-Lactate Dehydrogenase; D000410:Alanine Transaminase