The acetylcholine, GABA, glutamate triangle in the rat forebrain.
The present overview demonstrates that stress, fear, novelty, and learning processes are associated with arousal and increases of extracellular levels of cortical and hippocampal ACh, independently of increases of motor activity. Forebrain cholinergic systems appears to be regulated by GABAergic and glutamatergic inputs. However, several other neurotransmitter systems play a role.
Pepeu
G
G
Department of Preclinical and Clinical Pharmacology, University of Florence, Italy.
Blandina
P
P
D000109:Acetylcholine / Q000378:metabolism*; D000818:Animals; D003071:Cognition / Q000502:physiology; D018698:Glutamic Acid / Q000378:metabolism*; D009474:Neurons / Q000502:physiology; D016548:Prosencephalon / Q000166:cytology / Q000378:metabolism*; D051381:Rats / Q000378:metabolism*; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid; D000109:Acetylcholine