[Regional Centers of Pharmacovigilance: a complementary source of efficiency].
Spontaneous reporting remains so far the most used and cost-effective method for detecting new adverse reactions associated with marketed drugs. In France, this routine surveillance involves a network of 31 regional centres. In this study, the numbers of reported cases were compared between centres for three different drug-event associations having justified regulatory decisions. The number of reports differed greatly, both between centres and for the relative numbers of reports of each type in each centre. This study showed that the observed differences between centres probably resulted in a complementary and efficient surveillance of the whole French territory.
Mazé
F
F
Centre Régional de Pharmacovigilance et d'Information sur le Médicament de Bordeaux, France.
Bégaud
B
B
D016907:Adverse Drug Reaction Reporting Systems / Q000458:organization & administration* / Q000592:standards; D004358:Drug Therapy / Q000592:standards*; D064420:Drug-Related Side Effects and Adverse Reactions; D005602:France; D006801:Humans