[Finger tip necroses after dihydroergotamine medication in limited systemic scleroderma].
A 78 year old women developed acute fingertip necrosis just a few days after starting dihydroergotamine. The lesions healed in 3 weeks after the medication was stopped. The patient had suffered from Raynaud syndrome for 5 years and limited systemic sclerosis was diagnosed during the necrotic episode. Advanced age and microangiopathies are contraindications to the use of ergot-containing preparations.
Hahne
T
T
Klinik für Dermatologie und Allergologie, Augsburg.
Balda
B R
BR
D000368:Aged; D000075202:Contraindications; D004087:Dihydroergotamine / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005385:Fingers / Q000473:pathology*; D006801:Humans; D008881:Migraine Disorders / Q000188:drug therapy*; D009336:Necrosis; D011928:Raynaud Disease / Q000139:chemically induced* / Q000175:diagnosis; D012307:Risk Factors; D012595:Scleroderma, Systemic / Q000150:complications* / Q000175:diagnosis
D004087:Dihydroergotamine