Delaying surgery for thyroid cancer in pregnancy. A case report.
BACKGROUND
Management of thyroid cancer in pregnancy is controversial, as evidenced by disagreement in recommendations cited in leading obstetrics textbooks. Most thyroid carcinomas are well differentiated and pursue an indolent course. Many physicians recommend delay in surgical therapy until after delivery because of operative morbidity.


METHODS
A 27-year-old primigravida was found to have a solitary thyroid nodule at her initial obstetrics appointment. Fine needle aspiration was consistent with papillary carcinoma. Although detected at 8 weeks' estimated gestational age (EGA), the decision was made to defer surgical therapy until postpartum. The patient was referred to a tertiary care facility at 24 weeks' EGA secondary to rapid growth of the nodule. Surgery performed at that time revealed invasive disease.


CONCLUSIONS
Review of the literature suggests that delay in definitive therapy stems from early reports of fetal loss related to surgery, but contemporary data suggest that the risk of fetal loss related to surgery is minimal.
Driggers
R W
RW
Department of Obstetrics and Gynecology, National Naval Medical Center, Bethesda, MD 20889-5600, USA.
Kopelman
J N
JN
Satin
A J
AJ
D000328:Adult; D002291:Carcinoma, Papillary / Q000601:surgery*; D005260:Female; D005313:Fetal Death; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000601:surgery*; D012307:Risk Factors; D013964:Thyroid Neoplasms / Q000601:surgery*; D013997:Time Factors