title: Prevalence of micro- and macroalbuminuria in a Canarian population of type 2 diabetic patients. Relationship with blood pressure, lipid profile, obesity and metabolic control.
abstract: We performed a cross-sectional study on the prevalence of micro- and macroalbuminuria in a population of 288 Type 2 diabetic patients from Northern Gran Canaria Island (age 59 +/- 9.5, years; 48% male): 179 unselected patients referred by their family physicians, and 109 from our diabetes clinic. Sex, age, duration of diabetes and hypertension, blood pressure, body mass index, waist-hip ratio, HbA1c, creatinine, cholesterol (total and HDL), triglycerides, lipoprotein (a), and the presence of retinopathy, polyneuropathy, and coronary and cerebrovascular disease were assessed. The prevalences of micro- and macroalbuminuria were 28.5% and 11.8%. Among the patients referred by their family physicians, 32.4% were micro- and 6.1% macroalbuminuric. In our diabetes clinic, there were respectively 22% and 21% (with a higher prevalence of macroalbuminuria than in primary care, p < 0.05). Seventy-three percent were hypertensive in both settings. Prevalence was 31.5% for diabetic retinopathy, 21.0% for diabetic polyneuropathy, 8.1% for cerebrovascular disease, and 20.2% for coronary heart disease. The albumin excretion rate was significantly correlated with plasma creatinine levels, diastolic blood pressure, total cholesterol and the presence of coronary heart disease and diabetic retinopathy, but not with age, duration of diabetes or hypertension, body mass index, waist/hip ratio, glycated haemoglobin or triglycerides.
authors.affiliation: Endocrinology Dpt, Hospital, Las Palmas, Spain.
authors.forename: P L
authors.initials: PL
authors.lastname: De Pablos
authors.forename: J
authors.initials: J
authors.lastname: Martinez
authors.forename: M P
authors.initials: MP
authors.lastname: Martinez
authors.forename: J A
authors.initials: JA
authors.lastname: Doreste
mesh_terms: D000419:Albuminuria / Q000453:epidemiology*; D001266:Atlantic Islands / Q000453:epidemiology; D001786:Blood Glucose / Q000378:metabolism*; D001794:Blood Pressure; D001824:Body Constitution; D015992:Body Mass Index; D002561:Cerebrovascular Disorders / Q000453:epidemiology; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D003327:Coronary Disease / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000097:blood / Q000503:physiopathology* / Q000652:urine; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000503:physiopathology* / Q000652:urine; D003925:Diabetic Angiopathies / Q000453:epidemiology; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008055:Lipids / Q000097:blood*; D017270:Lipoprotein(a) / Q000097:blood; D008297:Male; D008875:Middle Aged; D009765:Obesity; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D002784:Cholesterol; D008076:Cholesterol, HDL; D006442:Glycated Hemoglobin; D008055:Lipids; D017270:Lipoprotein(a); D014280:Triglycerides