title: Lidocaine toxicity.
abstract: Local anesthetics are the most commonly used drugs in dentistry. The number of adverse reactions reported, particularly toxic reactions, are extraordinarily negligible. This article reports a case of lidocaine toxicity with its typical manifestation in a 37-yr-old healthy male. The toxic reaction followed transoral/transpharyngeal topical spraying of lidocaine preoperatively during preparation for general anesthesia. A review of dosages of the most commonly used local anesthetic drugs in dentistry and the management of a toxic reaction is presented. Clinicians need to be in a position to recognize and successfully manage this potential adverse reaction.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Boston University School of Dental Medicine, Massachusetts 02118, USA.
authors.forename: P
authors.initials: P
authors.lastname: Mehra
authors.forename: A
authors.initials: A
authors.lastname: Caiazzo
authors.forename: P
authors.initials: P
authors.lastname: Maloney
mesh_terms: D000287:Administration, Topical; D000328:Adult; D000766:Anesthesia, Dental; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D062787:Drug Overdose; D004830:Epilepsy, Tonic-Clonic / Q000139:chemically induced; D005597:Fractures, Open / Q000601:surgery; D006801:Humans; D007442:Intubation, Intratracheal; D008012:Lidocaine / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D008337:Mandibular Fractures / Q000601:surgery; D012307:Risk Factors; D014081:Tooth Extraction
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine