title: Xenotransplantation and the risk of retroviral zoonosis.
abstract: It is hypothesized that xenotransplantation could facilitate the emergence of new human pathogens. Retroviruses might pose the greatest public health risk because of the possibility of undetected transmission within a population. Evidence from naturally occurring retroviral zoonoses and cross-species infections by animal retroviruses provides a basis for reasoned speculation on the risks posed by xenotransplantation.
authors.affiliation: HIV/Retrovirus Diseases Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
authors.forename: J
authors.initials: J
authors.lastname: Brown
authors.forename: A L
authors.initials: AL
authors.lastname: Matthews
authors.forename: P A
authors.initials: PA
authors.lastname: Sandstrom
authors.forename: L E
authors.initials: LE
authors.lastname: Chapman
mesh_terms: D000818:Animals; D002986:Clinical Trials as Topic; D020077:Endogenous Retroviruses; D006801:Humans; D011634:Public Health; D012192:Retroviridae Infections; D012307:Risk Factors; D014183:Transplantation, Heterologous; D015047:Zoonoses