title: Mitral valve operation via Port Access versus median sternotomy.
abstract: OBJECTIVE
  The advantages and disadvantages of minimally invasive Port Access mitral valve operation have not been defined relative to standard median sternotomy. A study was therefore designed to delineate differences in outcome from mitral operation via Port Access versus sternotomy in comparable patients.
  
  
  METHODS
  The records of 41 consecutive patients undergoing isolated mitral valve replacement (n = 14) or repair (n = 27) were examined. All operations were performed using cardioplegic arrest through either median sternotomy (n = 20) or a small right anterolateral thoracotomy using an endoaortic clamp and catheter system (Heartport, Redwood City, CA) to arrest and decompress the heart (Port Access, n = 21).
  
  
  RESULTS
  Both groups were well matched for age, mitral pathology, ejection fraction, and comorbidity. except that Port Access patients were less likely to be female. Three patients had undergone previous cardiac operations. Surgical procedure time was longer for Port Access patients (384+/-80 vs. 263+/-41 min, P < 0.05). Port Access provided significantly smaller incision length (8+/-2 vs. 26+/-2 cm, P < 0.01) and similar or shorter hospital stay (6+/-4 vs. 7+/-3 days). Port Access provided excellent visualization of the mitral valve and subvalvular apparatus, generally better than sternotomy, to allow complex mitral valve repairs. The greatest advantage of Port Access mitral operation was that Port Access patients returned to normal activity more rapidly (4+/-2 vs. 9+/-1 weeks, P = 0.01) than did patients undergoing standard median sternotomy.
  
  
  CONCLUSIONS
  By avoiding a sternotomy, Port Access mitral valve operation provided a smaller incision and a dramatically more rapid return to normal activity than did median sternotomy. Port Access cardioplegic arrest with the Heartport system allowed visualization of the mitral valve superior to median sternotomy and has become the standard approach at this institution.
authors.affiliation: Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA. glowe001@mc.duke.edu
authors.forename: D D
authors.initials: DD
authors.lastname: Glower
authors.forename: K P
authors.initials: KP
authors.lastname: Landolfo
authors.forename: F
authors.initials: F
authors.lastname: Clements
authors.forename: N P
authors.initials: NP
authors.lastname: Debruijn
authors.forename: M
authors.initials: M
authors.lastname: Stafford-Smith
authors.forename: P K
authors.initials: PK
authors.lastname: Smith
authors.forename: F
authors.initials: F
authors.lastname: Duhaylongsod
mesh_terms: D016022:Case-Control Studies; D005260:Female; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000295:instrumentation / Q000379:methods; D008943:Mitral Valve / Q000601:surgery*; D013249:Sternum / Q000601:surgery*; D013908:Thoracotomy / Q000379:methods; D013997:Time Factors