title: [Total intravenous anesthesia with propofol is advantageous than thiopental-sevoflurane anesthesia in the recovery phase].
abstract: A randomized, prospective and multi-institutional study was performed to investigate whether different anesthetic methods affected differently the quality of recovery from anesthesia. Two hundred and eleven patients were allocated to one of two groups; total intravenous anesthesia (TIVA) with propofol and fentanyl (group P, n = 107) and general anesthesia with thiopental, sevoflurane and nitrous oxide (group TS, n = 104). The rapidity of emergence from anesthesia and postoperative incidence of nausea, vomiting, and headache were compared between the two groups. The group P showed significantly shorter emergence times for verbal command responses (7.4 +/- 5.6 min), extubation (10.0 +/- 6.0 min) and orientation (13.1 +/- 7.8 min) than the group TS (9.1 +/- 5.0 min, 11.7 +/- 6.2 min, 16.4 +/- 7.9 min, respectively). The postoperative incidence of vomiting was not significantly different between the two groups (3.7% in the group P and 9.6% in the group TS), but the postoperative incidences of nausea and headache were significantly lower in the group P compared with the group TS (10.3%, 17.8%, respectively in the group P and 34.6%, 29.8%, respectively in the group TS). We conclude that TIVA with propofol is advantageous than thiopental-sevoflurane anesthesia in the recovery phase.
authors.affiliation: Department of Anesthesiology, Kansai Medical University, Moriguchi.
authors.forename: H
authors.initials: H
authors.lastname: Matsumoto
authors.forename: K
authors.initials: K
authors.lastname: Shingu
authors.forename: K
authors.initials: K
authors.lastname: Numata
authors.forename: S
authors.initials: S
authors.lastname: Ogura
authors.forename: K
authors.initials: K
authors.lastname: Hanaoka
authors.forename: H
authors.initials: H
authors.lastname: Ito
authors.forename: T
authors.initials: T
authors.lastname: Kugimiya
authors.forename: T
authors.initials: T
authors.lastname: Kazama
authors.forename: K
authors.initials: K
authors.lastname: Ikeda
authors.forename: M
authors.initials: M
authors.lastname: Murakawa
authors.forename: K
authors.initials: K
authors.lastname: Mori
authors.forename: T
authors.initials: T
authors.lastname: Mashimo
authors.forename: I
authors.initials: I
authors.lastname: Yoshiya
authors.forename: M
authors.initials: M
authors.lastname: Morio
authors.forename: M
authors.initials: M
authors.lastname: Nakao
authors.forename: A
authors.initials: A
authors.lastname: Sato
mesh_terms: D000328:Adult; D000368:Aged; D000762:Anesthesia Recovery Period; D000768:Anesthesia, General; D000771:Anesthesia, Intravenous; D019162:Anesthetics, Combined; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D005260:Female; D005283:Fentanyl; D006801:Humans; D015994:Incidence; D008297:Male; D008738:Methyl Ethers; D008875:Middle Aged; D009609:Nitrous Oxide; D011183:Postoperative Complications / Q000453:epidemiology; D015742:Propofol; D011446:Prospective Studies; D000077149:Sevoflurane; D013874:Thiopental
chemical_list: D019162:Anesthetics, Combined; D018685:Anesthetics, Inhalation; D018686:Anesthetics, Intravenous; D008738:Methyl Ethers; D000077149:Sevoflurane; D013874:Thiopental; D009609:Nitrous Oxide; D005283:Fentanyl; D015742:Propofol