Neuropathic pain: new insights, new interventions.
The past decade has seen great progress in understanding its causes and in finding new drugs that promise great benefit. An early outcome of the research has been the observation that the new drugs do not blunt normal pain sensation--a pattern beginning to find explanation through the realization that neural pain circuits rewire themselves, both anatomically and biochemically, after nerve injury.
Bennett
G J
GJ
Allegheny University of the Health Sciences, Philadelphia, USA.
D000700:Analgesics / Q000494:pharmacology*; D006801:Humans; D009420:Nervous System / Q000187:drug effects / Q000503:physiopathology*; D009437:Neuralgia / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology*; D016194:Receptors, N-Methyl-D-Aspartate / Q000037:antagonists & inhibitors; D020196:Trauma, Nervous System
D000700:Analgesics; D016194:Receptors, N-Methyl-D-Aspartate