title: Juvenile symptomatic Rathke's cleft cyst--case report.
abstract: A 14-year-old girl presented with a rare symptomatic Rathke's cleft cyst manifesting as diabetes insipidus and growth retardation. Neuroimaging demonstrated the suprasellar cyst. Computed tomography showed the cyst as an isodense area with enhancement, and magnetic resonance imaging showed an hyperintense area on both T1- and T2-weighted images. Histological examination showed the cyst was consistent with Rathke's cleft cyst. Symptomatic Rathke's cleft cysts usually occur in middle-aged adults. Juvenile cases tend to present with diabetes insipidus, and the cyst content may include more mucopolysaccharides or hemosiderin degradation products.
authors.affiliation: Department of Neurosurgery, Kitasato University School of Medicine, Kanagawa.
authors.forename: T
authors.initials: T
authors.lastname: Tanaka
authors.forename: H
authors.initials: H
authors.lastname: Oka
authors.forename: N
authors.initials: N
authors.lastname: Kawano
authors.forename: I
authors.initials: I
authors.lastname: Kobayashi
authors.forename: H
authors.initials: H
authors.lastname: Saegusa
authors.forename: K
authors.initials: K
authors.lastname: Fujii
mesh_terms: D000293:Adolescent; D000328:Adult; D003397:Craniopharyngioma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D003919:Diabetes Insipidus / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D010902:Pituitary Gland / Q000473:pathology / Q000601:surgery; D010911:Pituitary Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D014057:Tomography, X-Ray Computed