title: i-STAT hand-held point-of-care analyzer for dialysis units.
abstract: The i-STAT hand-held analyzer assays ten tests including electrolytes, gases, urea, glucose, ionized calcium, and hematocrit. Eight different cartridges assay one to eight tests. We have previously confirmed or demonstrated that accuracy and precision for blood assays are comparable to accepted laboratory methods. We now report similar results for hemodialysis dialysate and peritoneal dialysis effluent. The i-STAT analyzer is simple to use, and dialysis nurses produced accurate results with 20 min training. The results are viewed digitally on the analyzer and automatically on a small attachable printer. i-STAT blood analysis is most valuable when results are desired immediately, anywhere, including before, during and after dialysis in hemodialysis units. Hemodialysate analysis using i-STAT can be most valuable for rapidly checking dialysis machine function such as dialysate mixing and conductivity and ramping results and dialysate concentrations prepared in the unit. Peritoneal effluent analysis is useful for rapid evaluation of membrane function.
authors.affiliation: Memorial University and Dialysis Unit of the General Hospital, St. John's, Nfld., Canada.
authors.forename: M H
authors.initials: MH
authors.lastname: Gault
authors.forename: C E
authors.initials: CE
authors.lastname: Harding
authors.forename: S
authors.initials: S
authors.lastname: Duffett
authors.forename: L
authors.initials: L
authors.lastname: Longerich
mesh_terms: D002118:Calcium / Q000032:analysis; D002624:Chemistry, Clinical / Q000295:instrumentation*; D002712:Chlorides / Q000032:analysis; D016001:Confidence Intervals; D015314:Dialysis Solutions / Q000737:chemistry; D005947:Glucose / Q000032:analysis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D010530:Peritoneal Dialysis / Q000295:instrumentation*; D019095:Point-of-Care Systems / Q000191:economics / Q000706:statistics & numerical data*; D011188:Potassium / Q000032:analysis; D006435:Renal Dialysis / Q000295:instrumentation*; D015203:Reproducibility of Results; D012964:Sodium / Q000032:analysis; D013997:Time Factors; D014508:Urea / Q000032:analysis; D014556:Urine / Q000737:chemistry
chemical_list: D002712:Chlorides; D015314:Dialysis Solutions; D014508:Urea; D012964:Sodium; D005947:Glucose; D011188:Potassium; D002118:Calcium