title: Pleural carcinosis confirmed by adjuvant cytological methods: a case report.
abstract: We describe a case of a 43-yr-old woman presenting a progressive pleural effusion. The patient was known to have an acute myeloid leukemia in complete remission after allogenic bone marrow transplantation. Suspicion of pleural carcinosis was raised cytologically and confirmed by immunocytochemistry, DNA-cytometry, and atomic force microscopy. We emphasize the use of these additional methods for the distinction of adenocarcinoma cells in effusions from reactive mesothelial cells.
authors.affiliation: Institute of Cytopathology, Heinrich Heine University, Düsseldorf, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Motherby
authors.forename: B
authors.initials: B
authors.lastname: Ross
authors.forename: M
authors.initials: M
authors.lastname: Kube
authors.forename: U
authors.initials: U
authors.lastname: Germing
authors.forename: A
authors.initials: A
authors.lastname: Heyll
authors.forename: C
authors.initials: C
authors.lastname: Aul
authors.forename: S
authors.initials: S
authors.lastname: Braunstein
authors.forename: H E
authors.initials: HE
authors.lastname: Gabbert
authors.forename: A
authors.initials: A
authors.lastname: Böcking
mesh_terms: D000208:Acute Disease; D000230:Adenocarcinoma / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism; D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D004273:DNA, Neoplasm / Q000032:analysis; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D019044:Image Cytometry / Q000379:methods; D007150:Immunohistochemistry; D007951:Leukemia, Myeloid / Q000150:complications; D018625:Microscopy, Atomic Force / Q000379:methods; D016066:Pleural Effusion, Malignant / Q000473:pathology*; D010997:Pleural Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; D004273:DNA, Neoplasm