Lhermitte-Duclos disease: first report in Taiwan.
We report a case of Lhermitte-Duclos disease (dysplastic gangliocytoma of the cerebellum), an uncommon disorder of uncertain pathogenesis characterized by disarrangement of the normal cerebellar laminar cytoarchitecture. A 40-year-old man was admitted because of vomiting and syncope of a few days' duration, and a 2-month history of intermittent headaches and unsteady gait. A computed tomographic scan of the patient's head showed obstructive hydrocephalus due to displacement of the fourth ventricle by a large, nonenhancing cerebellar mass. The magnetic resonance images of the brain also revealed a space-occupying lesion within the right cerebellum with unusual septation. After surgery, the histologic examination confirmed the diagnosis of Lhermitte-Duclos disease. This is the first report of Lhermitte-Duclos disease in Taiwan.
Lee
J D
JD
Department of Neurology, Chang Gung Memorial Hospital, Taipei, Taiwan.
Ho
Y S
YS
Chen
S T
ST
Lin
T K
TK
Ro
L S
LS
Lee
T H
TH
D000328:Adult; D002528:Cerebellar Neoplasms / Q000175:diagnosis* / Q000601:surgery; D005729:Ganglioneuroma / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008297:Male