[The prognostic importance of the immunohistochemical study of protein p53 in transitional-cell bladder tumors].
In an immunohistochemical investigation designed to study a mutated p53 protein in transitional-cell tumours (n = 44) we succeeded in identifying the presence of two types of transitional-cell tumours of human urinary bladder, such as p53 immunopositive and p53 immunonegative transitional-cell tumours. Thus, the results of the immunohistochemical investigation into the protein p53 were found out to directly correlate with the clinical course of transitional-cell tumours, that are held to be of great differential-diagnostic and prognostic significance.
Gaĭyrov
A G
AG
Romanenko
A M
AM
Klimenko
I A
IA
Sakalo
V S
VS
Grigorenko
V N
VN
Nepomniashchiĭ
V N
VN
D002295:Carcinoma, Transitional Cell / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D009154:Mutation / Q000502:physiology; D011379:Prognosis; D016159:Tumor Suppressor Protein p53 / Q000235:genetics / Q000378:metabolism*; D001743:Urinary Bladder / Q000378:metabolism; D001749:Urinary Bladder Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000378:metabolism
D016159:Tumor Suppressor Protein p53