title: [Chronic, infantile, neurologic, cutaneous and articular syndrome (CINCA) in an infant].
abstract: BACKGROUND
  CINCA syndrome is a clinical syndrome of unclear etiology, characterized by a chronic multi-organ inflammatory process unsusceptible to treatment.
  
  
  METHODS
  An 18-month-old boy was admitted because he suffered, since the age of 2 months, from cutaneous, articular and neurological changes, lymphadenopathy, hepatosplenomegaly, choroiditis and psychosomatic development retardation. These clinical symptoms were unsusceptible to anti-inflammatory and antihistaminic drugs. Rehabilitation was not effective either.
  
  
  CONCLUSIONS
  A long-term clinical observation is required before sustained multi-organ changes beginning in early childhood and exclusion of other chronic inflammatory diseases enable the diagnosis of CINCA syndrome.
authors.affiliation: Clinique du nourrisson, institut Monument, centre de santé de l'enfant, Varsovie, Pologne.
authors.forename: B
authors.initials: B
authors.lastname: Milewska-Bobula
authors.forename: B
authors.initials: B
authors.lastname: Lipka
authors.forename: K
authors.initials: K
authors.lastname: Rowecka-Trzebicka
authors.forename: K
authors.initials: K
authors.lastname: Rostropowicz-Denisiewicz
authors.forename: A
authors.initials: A
authors.lastname: Romicka
authors.forename: J M
authors.initials: JM
authors.lastname: Witwicki
mesh_terms: D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D006634:Histamine H1 Antagonists / Q000627:therapeutic use; D006801:Humans; D007223:Infant; D007592:Joint Diseases / Q000175:diagnosis*; D008297:Male; D009422:Nervous System Diseases / Q000175:diagnosis*; D012871:Skin Diseases / Q000175:diagnosis*; D013577:Syndrome
chemical_list: D000893:Anti-Inflammatory Agents; D006634:Histamine H1 Antagonists