Multiresidue supercritical fluid extraction method for the recovery at low ppb levels of three sulfonamides from fortified chicken liver.
A supercritical fluid extraction (SFE) method is proposed for the recovery of three sulfonamides from chicken liver. Samples were extracted at 680 bar and 40 degrees C using unmodified carbon dioxide and were collected free of co-extracted artifactual material on an in-line neutral alumina sorbent bed. High recoveries of sulfamethazine (SMZ), sulfadimethoxine (SDM) and sulfaquinoxaline (SQX) were obtained from chicken liver samples fortified at levels from 1000 to 50 ppm.
Maxwell
R J
RJ
U.S. Department of Agriculture, Agricultural Research Service, Eastern Regional Research Center, Wyndmoor, PA 19038, USA.
Lightfield
A R
AR
D000818:Animals; D002645:Chickens; D002845:Chromatography / Q000379:methods*; D008099:Liver / Q000737:chemistry*; D012680:Sensitivity and Specificity; D013056:Spectrophotometry, Ultraviolet; D013412:Sulfadimethoxine / Q000032:analysis*; D013418:Sulfamethazine / Q000032:analysis*; D013428:Sulfaquinoxaline / Q000032:analysis*
D013412:Sulfadimethoxine; D013418:Sulfamethazine; D013428:Sulfaquinoxaline