title: MCG simulations with a realistic heart-torso model.
abstract: Magnetocardiograms (MCG's) simulated with a high-resolution heart-torso model of an adult subject were compared with measured MCG's acquired from the same individual. An exact match of the measured and simulated MCG's was not found due to the uncertainties in tissue conductivities and cardiac source positions. However, general features of the measured MCG's were reasonably represented by the simulated data for most, but not all of the channels. This suggests that the model accounts for the most important mechanisms underlying the genesis of MCG's and may be useful for cardiac magnetic field modeling under normal and diseased states. MCG's were simulated with a realistic finite-element heart-torso model constructed from segmented magnetic resonance images with 19 different tissue types identified. A finite-element model was developed from the segmented images. The model consists of 2.51 million brick-shaped elements and 2.58 million nodes, and has a voxel resolution of 1.56 x 1.56 x 3 mm. Current distributions inside the torso and the magnetic fields and MCG's at the gradiometer coil locations were computed. MCG's were measured with a Philips twin Dewar first-order gradiometer SQUID-system consisting of 31 channels in one tank and 19 channels in the other.
authors.affiliation: Department of Bioengineering, University of Washington, Seattle 98195, USA. ceon@u.washington.edu
authors.forename: C
authors.initials: C
authors.lastname: Ramon
authors.forename: P
authors.initials: P
authors.lastname: Czapski
authors.forename: J
authors.initials: J
authors.lastname: Haueisen
authors.forename: L L
authors.initials: LL
authors.lastname: Huntsman
authors.forename: H
authors.initials: H
authors.lastname: Nowak
authors.forename: G H
authors.initials: GH
authors.lastname: Bardy
authors.forename: U
authors.initials: U
authors.lastname: Leder
authors.forename: Y
authors.initials: Y
authors.lastname: Kim
authors.forename: J A
authors.initials: JA
authors.lastname: Nelson
mesh_terms: D000328:Adult; D055592:Biophysical Phenomena; D001703:Biophysics; D003198:Computer Simulation; D004553:Electric Conductivity; D020342:Finite Element Analysis; D006321:Heart / Q000502:physiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008280:Magnetics; D008297:Male; D008955:Models, Cardiovascular