Live birth from a zygote cryopreserved for 8 years.
After a cryopreservation period of 8 years, four zygotes were thawed and transferred to the patient's uterine cavity. A singleton pregnancy resulted in the delivery of a normal male. This case report offers evidence that long terms of cryopreservation are consistent with full developmental potential post-thaw, and encourages further examination of imposing limits on length of storage of frozen concepti.
Go
K J
KJ
Pennsylvania Reproductive Associates, Pennsylvania Hospital, Department of Obstetrics and Gynecology, Philadelphia 19107, USA.
Corson
S L
SL
Batzer
F R
FR
Walters
J L
JL
D000328:Adult; D015925:Cryopreservation; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D007231:Infant, Newborn; D007247:Infertility, Female / Q000628:therapy; D008297:Male; D008875:Middle Aged; D011247:Pregnancy; D011256:Pregnancy Outcome; D013997:Time Factors; D015053:Zygote