[Mucocutaneous fungal infection in AIDS patients].
Human immunodeficiency virus (HIV) infection is unique among the cutaneous fungal infections caused by defects of the cell-mediated immune system. A complex interplay exists in the host between fungal virulence factors favoring disease, and immune and non-immune host mechanisms defending against disease. Cell-mediated immunity appears of paramount importance in defense against histoplasmosis, cryptococcosis, mucocutaneous candidiasis, and dermatophytosis. Mucocutaneous candidiasis is especially common in patients with HIV infection. Anti-fungal medicines were effective against candidiasis. However, anti-fungal medicine-resistant candida has been observed. Anti-fungal ointment was effective against dermatophytosis and seborrheic dermatitis. No cases of cutaneous fungal infection resistant to anti-fungal medicine have been observed.
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Department of Dermatology, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama 236-0004.
D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy*; D002178:Candidiasis, Chronic Mucocutaneous / Q000188:drug therapy*; D003881:Dermatomycoses / Q000188:drug therapy*; D006801:Humans