title: Depression subtyping: treatment implications.
abstract: The complexity of subtyping depression and the implications that such subtyping has on treatment choices are discussed in this article. The most recent edition of the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) directs clinicians to classify the mood disorders in depressed patients as unipolar, bipolar, due to a general medical condition, or due to substance abuse. The focus of this article is unipolar (major depression and dysthymia) and bipolar I and II disorders with and without feature specifiers for atypical depression, seasonal affective disorder, psychotic depression, and postpartum depression. Anxious depression, which is not a DSM-IV classification, is also reviewed.
authors.affiliation: Department of Psychiatry, University of Minnesota, Minneapolis 55455, USA.
authors.forename: P J
authors.initials: PJ
authors.lastname: Clayton
mesh_terms: D000928:Antidepressive Agents / Q000627:therapeutic use*; D001008:Anxiety Disorders / Q000145:classification / Q000188:drug therapy; D001714:Bipolar Disorder / Q000145:classification / Q000175:diagnosis / Q000188:drug therapy; D015897:Comorbidity; D003866:Depressive Disorder / Q000145:classification* / Q000175:diagnosis / Q000188:drug therapy*; D019263:Dysthymic Disorder / Q000145:classification / Q000175:diagnosis / Q000188:drug therapy; D006801:Humans; D008996:Monoamine Oxidase Inhibitors / Q000627:therapeutic use; D010789:Phototherapy; D016574:Seasonal Affective Disorder / Q000145:classification / Q000175:diagnosis / Q000188:drug therapy; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use; D012892:Sleep Deprivation; D016896:Treatment Outcome
chemical_list: D000928:Antidepressive Agents; D008996:Monoamine Oxidase Inhibitors; D017367:Selective Serotonin Reuptake Inhibitors