title: Sexually transmitted disease acquisition among women infected with human immunodeficiency virus type 1.
abstract: Recent evidence suggests that sexually transmitted diseases (STDs) enhance the transmission of human immunodeficiency virus (HIV) type 1. In 143 HIV-infected women enrolled in a university-based longitudinal HIV clinic over 16 months (mean), the STD point prevalence was examined at enrollment and the cumulative prevalence was calculated at follow-up. At enrollment, 35 women (25%) had > or = 1 STD. These included trichomoniasis in 16 women (11%); syphilis, 9 (6%); genital herpes, 8 (6%); gonorrhea, 5 (4%); chlamydia, 5 (4%); genital warts, 2 (1%); and pelvic inflammatory disease (PID), 1 (1%). STDs were found in 55 (42%) of the 125 patients who returned for at least one follow-up visit: trichomoniasis in 23 (18%); genital herpes, 20 (12%); gonorrhea, 9 (7%); syphilis, 7 (6%); genital warts, 7 (6%); chlamydia, 5 (4%); and PID, 4 (3%). Despite counseling at both enrollment and follow-up, these women had a very high cumulative prevalence of STDs, indicating persistent high-risk sexual behavior.
authors.affiliation: Washington University School of Medicine, Department of Internal Medicine (Infectious Disease Division), St. Louis, Missouri 63110, USA.
authors.forename: S J
authors.initials: SJ
authors.lastname: Bersoff-Matcha
authors.forename: M M
authors.initials: MM
authors.lastname: Horgan
authors.forename: V J
authors.initials: VJ
authors.lastname: Fraser
authors.forename: L M
authors.initials: LM
authors.lastname: Mundy
authors.forename: B P
authors.initials: BP
authors.lastname: Stoner
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D015658:HIV Infections / Q000150:complications*; D015497:HIV-1; D006801:Humans; D008137:Longitudinal Studies; D008875:Middle Aged; D008923:Missouri / Q000453:epidemiology; D012309:Risk-Taking; D012725:Sexual Behavior; D012749:Sexually Transmitted Diseases / Q000453:epidemiology* / Q000635:transmission; D015231:Sexually Transmitted Diseases, Bacterial / Q000453:epidemiology / Q000635:transmission; D015229:Sexually Transmitted Diseases, Viral / Q000453:epidemiology / Q000635:transmission; D014245:Trichomonas Infections / Q000453:epidemiology / Q000635:transmission