Granulomatous inflammation and the transmission of infection: schistosomiasis--and TB too?
Immune-dependent granulomatous inflammation is important in the pathogenesis of both schistosomiasis and tuberculosis. A case has previously been made for a role for schistosome egg-induced granulomas in the onward transmission of infection. Here, Mike Doenhoff suggests that a similar hypothesis applies to tuberculosis.
Doenhoff
M J
MJ
School of Biological Sciences, University of Wales, Bangor, Gwynedd, UK. m.doenhoff@bangor.ac.uk
D017088:AIDS-Related Opportunistic Infections / Q000382:microbiology / Q000469:parasitology; D000818:Animals; D006099:Granuloma / Q000382:microbiology* / Q000469:parasitology* / Q000473:pathology; D006801:Humans; D051379:Mice; D009169:Mycobacterium tuberculosis; D010270:Parasite Egg Count; D011817:Rabbits; D012550:Schistosoma mansoni; D012555:Schistosomiasis mansoni / Q000276:immunology / Q000473:pathology / Q000635:transmission*; D014376:Tuberculosis / Q000150:complications / Q000276:immunology / Q000473:pathology / Q000635:transmission*