title: Cytostatic activity of some compounds from the unsaponifiable fraction obtained from virgin olive oil.
abstract: Oleuropein, tyrosol, squalene and the fraction of sterols and triterpenoid dialcohols from the unsaponifiable fraction obtained from virgin olive oil have been tested for possible cytostatic activity against McCoy cells, using 6-mercaptopurine as a positive control. The samples of sterols and triterpenic dialcohols showed a strong activity.
authors.affiliation: Laboratori do Farmacognosia, Universidad de Sevilla, 41012 Seville, Spain
authors.forename: M T
authors.initials: MT
authors.lastname: Saenz
authors.forename: M D
authors.initials: MD
authors.lastname: Garcia
authors.forename: M C
authors.initials: MC
authors.lastname: Ahumada
authors.forename: V
authors.initials: V
authors.lastname: Ruiz
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000302:isolation & purification / Q000494:pharmacology*; D002455:Cell Division / Q000187:drug effects; D002460:Cell Line; D006801:Humans; D057888:Iridoid Glucosides; D039823:Iridoids; D000069463:Olive Oil; D010626:Phenylethyl Alcohol / Q000031:analogs & derivatives / Q000494:pharmacology; D010938:Plant Oils / Q000737:chemistry*; D011714:Pyrans / Q000494:pharmacology; D013185:Squalene / Q000494:pharmacology; D013261:Sterols / Q000494:pharmacology; D014315:Triterpenes / Q000494:pharmacology
chemical_list: D000972:Antineoplastic Agents, Phytogenic; D057888:Iridoid Glucosides; D039823:Iridoids; D000069463:Olive Oil; D010938:Plant Oils; D011714:Pyrans; D013261:Sterols; D014315:Triterpenes; C011867:4-hydroxyphenylethanol; C002769:oleuropein; D013185:Squalene; D010626:Phenylethyl Alcohol