The hypothesis of an ambient level of acetylcholine in the central nervous system.
Recent ultrastructural data demonstrate the largely asynaptic character of the cholinergic innervation in many regions of adult rat brain. These data favour the hypothesis of a diffuse transmission/modulation by acetylcholine in the CNS and, by way of consequence, that of a persistent, low level of acetylcholine in the extracellular space.
Descarries
L
L
Département de pathologie, Faculté de médecine, Université de Montréal, Québec, Canada.
D000109:Acetylcholine / Q000378:metabolism*; D000818:Animals; D001481:Basal Metabolism; D001921:Brain / Q000378:metabolism*; D017729:Presynaptic Terminals / Q000378:metabolism*; D051381:Rats; D009435:Synaptic Transmission / Q000502:physiology
D000109:Acetylcholine