title: [Pathology of the ureterovesical junction in neurogenic bladders in children and adolescents. A retrospective study of 119 patients].
abstract: Ureterovesical junction dysfunction in congenital or acquired neurogenic bladders represents a threat for the renal parenchyma. In order to evaluate the incidence, mechanisms of development and preventive and curative treatments proposed in diseases of the ureterovesical junction associated with neurogenic bladders, the files of 119 children were retrospectively evaluated. 68 patients suffered from congenital neurogenic bladder and 51 had an acquired neurogenic bladder. In the congenital neurogenic bladder group, vesico-ureteric reflux was observed in 22 cases (32%) and dilatation was observed in 18 cases (26.5%), while 21 patients had both dilatation and reflux. In the acquired neurogenic bladder group, reflux was observed in 8 cases (16%) and dilatation was observed in 3 cases (10%), one of whom had both reflux and dilatation. The predominant mechanism of decompensation of the ureterovesical junction in the two groups was a combination of low compliance and high peripheral resistance. In patients with abnormalities of the ureterovesical junction, the incidence of associated parenchymal lesions was similar (30%) whether neurogenic bladder was congenital or acquired. The disparities between these two comparable patient groups, the preventive and curative treatments proposed and their results are analysed in comparison with the data reported in the literature.
authors.affiliation: Service d'Urologie de l'Enfant et de l'Adolescent, Hôpital Saint-Joseph, Paris.
authors.forename: H
authors.initials: H
authors.lastname: Lottmann
authors.forename: G
authors.initials: G
authors.lastname: Rousseau
authors.forename: M J
authors.initials: MJ
authors.lastname: Rouffet
authors.forename: D
authors.initials: D
authors.lastname: Yepremian
authors.forename: M
authors.initials: M
authors.lastname: Bernuy
mesh_terms: D000293:Adolescent; D002648:Child; D004108:Dilatation, Pathologic / Q000473:pathology; D006801:Humans; D011859:Radiography; D012189:Retrospective Studies; D014513:Ureter / Q000473:pathology*; D001743:Urinary Bladder / Q000473:pathology*; D001750:Urinary Bladder, Neurogenic / Q000151:congenital / Q000000981:diagnostic imaging / Q000473:pathology* / Q000628:therapy; D014718:Vesico-Ureteral Reflux / Q000473:pathology