title: The association between rates of wear in retrieved acetabular components and the radius of the femoral head.
abstract: Current evidence suggests that loosening of the acetabular socket is related to the volume of ultra-high molecular weight polyethylene wear debris generated at the articulating surfaces, through a process of bone resorption. Therefore it is important that the rate of volumetric wear is minimized in an attempt to extend the useful life of the procedure. Laboratory evidence indicates that a reduction in sliding distance would be beneficial in achieving this target and may be attained by a reduction in femoral head radius. To investigate the relationship between femoral head size and the rates of both volumetric wear and penetration, 200 acetabular components were retrieved at the time of revision surgery. The joints had femoral heads ranging in size from 11.1 to 19.8 mm radius. For those sockets that were loose at revision surgery, a significant correlation was observed, between the rate of volumetric wear and the radius of the femoral head. For this cohort an increase in radius of 1 mm resulted in an increased rate of volumetric wear of 5.1 (SE 1.4) mm3/yr. However, the explained variance in the regression was low and exemplifies the multifactorial nature of the wear process. In particular, it is anticipated that the activity of the patient will have a significant effect on the rate at which the debris is produced. No significant correlation was observed between the rate of linear wear and femoral head radius. These results would indicate a benefit in using head sizes of a smaller radius, which generate debris at a reduced rate, and therefore require more time to accumulate large volumes of wear products.
authors.affiliation: Centre for Biomedical Engineering, University of Durham.
authors.forename: R M
authors.initials: RM
authors.lastname: Hall
authors.forename: P
authors.initials: P
authors.lastname: Siney
authors.forename: A
authors.initials: A
authors.lastname: Unsworth
authors.forename: B M
authors.initials: BM
authors.lastname: Wroblewski
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D001862:Bone Resorption; D005270:Femur Head / Q000033:anatomy & histology* / Q000601:surgery; D006622:Hip Prosthesis / Q000592:standards*; D006801:Humans; D008875:Middle Aged; D010027:Osteotomy; D011095:Polyethylenes / Q000592:standards; D011475:Prosthesis Failure; D012044:Regression Analysis; D012086:Reoperation
chemical_list: D011095:Polyethylenes; C111601:ultra-high molecular weight polyethylene