[The action of an aqueous extract of Aloe barbadensis Miller in an in-vitro culture of Trichomonas vaginalis].
The antiparasitic action of an aqueous extract of Aloe barbadensis Miller against and in vitro culture of Trichomonas vaginalis was studied for the first time. Three strains of this parasite were used for the study. Taking an initial concentration of 400 mg/mL of the extract, double serial dilutions were performed, and final concentrations based on the dried weight of the extract were 10.4, 20.8, 41, 83, and 160 mg/mL. Within 24 hours, percentages of inhibition greater than 50% were obtained from concentrations of 20.8 micrograms/mL. Similar results were obtained at 48, and 72 hours, with a lower concentration, the inhibition of growth was greater than 50%.
Rojas
L
L
Instituto de Medicina Tropical Pedro Kourí.
Matamoros
M
M
Garrido
N
N
Finlay
C
C
D000504:Aloe; D000818:Animals; D000994:Antitrichomonal Agents / Q000494:pharmacology*; D003864:Depression, Chemical; D004305:Dose-Response Relationship, Drug; D005260:Female; D006801:Humans; D010936:Plant Extracts / Q000494:pharmacology; D010946:Plants, Medicinal; D013997:Time Factors; D014246:Trichomonas vaginalis / Q000187:drug effects* / Q000302:isolation & purification
D000994:Antitrichomonal Agents; D010936:Plant Extracts