Effect of minCD on FtsZ ring position and polar septation in Bacillus subtilis.
We examined the pattern of FtsZ localization in a Bacillus subtilis minCD mutant. When grown in minimal medium, the majority (approximately 89%) of the minCD mutant cells with an FtsZ ring had a single, medially positioned FtsZ ring. These results indicate that genes in addition to minCD function to restrict the number and position of FtsZ rings. When grown in rich medium, greater than 50% of the minCD mutant cells had multiple FtsZ rings, indicating significant differences in regulation of FtsZ ring formation based on growth medium.
Levin
P A
PA
Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Shim
J J
JJ
Grossman
A D
AD
D000251:Adenosine Triphosphatases / Q000235:genetics / Q000378:metabolism*; D001412:Bacillus subtilis / Q000235:genetics / Q000254:growth & development / Q000378:metabolism*; D001426:Bacterial Proteins / Q000235:genetics / Q000378:metabolism*; D017124:Conserved Sequence; D003470:Culture Media; D003598:Cytoskeletal Proteins; D029968:Escherichia coli Proteins; D005798:Genes, Bacterial; D009154:Mutation
D001426:Bacterial Proteins; D003470:Culture Media; D003598:Cytoskeletal Proteins; D029968:Escherichia coli Proteins; C071525:FtsZ protein, Bacteria; C080466:MinC protein, Bacteria; D000251:Adenosine Triphosphatases; C072069:MinD protein, E coli