title: Primary lymphoma of the heart: report of a case with histological diagnosis of the transvenously biopsied intracardiac tumor.
abstract: Primary cardiac lymphoma is an extremely rare disease and is associated with a high mortality. In most cases, lymphomatous involvement of the heart and/or pericardium occurs as a late manifestation of disseminated disease. Primary cardiac lymphoma is treatable when appropriately diagnosed. We report the case of an immunocompetent 69-year-old patient who presented with signs of dyspnea and a transmural mass infiltrating the apical section of both ventricles. Examination of the tissue obtained by transvenous biopsy revealed high-grade non-Hodgkin's lymphoma of B-cell lineage. The patient was treated successfully with CHOP chemotherapy. This case demonstrates that early diagnosis and intensive chemotherapy might contribute to a better prognosis for patients with malignant lymphoma of the heart.
authors.affiliation: Department of Internal Medicine I, University Hospital, Homburg/Saar, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Daus
authors.forename: W
authors.initials: W
authors.lastname: Bay
authors.forename: S
authors.initials: S
authors.lastname: Harig
authors.forename: G
authors.initials: G
authors.lastname: Schneider
authors.forename: W
authors.initials: W
authors.lastname: Feiden
authors.forename: H
authors.initials: H
authors.lastname: Schieffer
mesh_terms: D000368:Aged; D001706:Biopsy / Q000379:methods; D006338:Heart Neoplasms / Q000473:pathology*; D006801:Humans; D008223:Lymphoma / Q000473:pathology*; D008297:Male