title: Laparoscopic ovarian transposition for pelvic malignancies: indications and functional outcomes.
abstract: OBJECTIVE
  To assess the indications and effectiveness of laparoscopic ovarian transposition before pelvic irradiation for a gynecologic cancer.
  
  
  METHODS
  Prospective study.
  
  
  METHODS
  A gynecologic oncology department in a French anti-cancer center.
  
  
  METHODS
  Twenty-four patients treated for pelvic cancer.
  
  
  METHODS
  Laparoscopic ovarian transposition to paracolic gutters. Uterine conservation in 18 patients.
  
  
  METHODS
  Clinical and laboratory follow-up tests of ovarian function.
  
  
  RESULTS
  Bilateral laparoscopic ovarian transposition was achieved in 22 patients (94%). Twelve patients were treated for clear cell adenocarcinoma of the cervix and/or upper vagina, 6 patients for invasive squamous cervical carcinoma, 3 patients for pelvic sarcoma, 1 patient for recurrent cervical cancer to the upper vagina, 1 patient for ependymoma of the cauda equina, and 1 patient for ovarian dysgerminoma. Ovarian preservation was achieved in 79%. Three pregnancies were obtained.
  
  
  CONCLUSIONS
  Laparoscopic ovarian transposition is a safe and effective procedure for preserving ovarian function. Bilateral ovarian transposition should be performed. The main indications for laparoscopic ovarian transposition are a patient with a small invasive cervical carcinoma (<2 cm) in a patient <40 years of age who is treated by initial laparoscopically assisted vaginal radical hysterectomy and a patient with a clear cell adenocarcinoma of the cervix and upper vagina.
authors.affiliation: Institut Gustave Roussy, Villejuif, France.
authors.forename: P
authors.initials: P
authors.lastname: Morice
authors.forename: D
authors.initials: D
authors.lastname: Castaigne
authors.forename: C
authors.initials: C
authors.lastname: Haie-Meder
authors.forename: P
authors.initials: P
authors.lastname: Pautier
authors.forename: J
authors.initials: J
authors.lastname: El Hassan
authors.forename: P
authors.initials: P
authors.lastname: Duvillard
authors.forename: A
authors.initials: A
authors.lastname: Gerbaulet
authors.forename: G
authors.initials: G
authors.lastname: Michel
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D006801:Humans; D010535:Laparoscopy; D010053:Ovary / Q000601:surgery*; D010386:Pelvic Neoplasms / Q000601:surgery*; D011446:Prospective Studies; D016896:Treatment Outcome