title: [Use of exogenous ribonuclease for improvement of Lactobacillus biological properties].
abstract: The influence of exogenous RNAse on the dynamics of the acid formation by the industrial strain 8R-A3 of Lactobacillus plantarum, its antibiotic sensitivity and antagonistic activity was studied. In the presence of the RNAase growth stimulating dose both a decrease of the culture lag-phase and a more intensive accumulation of lactic acid in the incubation medium resulting in an increase of the Lactobacillus antagonistic activity were observed. It was shown that RNAase increased the Lactobacillus stability to tetracycline and erythromycin by 32 to 57 per cent as compared to the control.
authors.affiliation: Kazan State University.
authors.forename: A I
authors.initials: AI
authors.lastname: Kolpakov
authors.forename: D V
authors.initials: DV
authors.lastname: Iunusov
authors.forename: A V
authors.initials: AV
authors.lastname: Garusov
authors.forename: F G
authors.initials: FG
authors.lastname: Kupriianova-Ashina
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D003470:Culture Media; D004305:Dose-Response Relationship, Drug; D004722:Endoribonucleases / Q000494:pharmacology*; D004917:Erythromycin / Q000494:pharmacology; D019344:Lactic Acid / Q000378:metabolism*; D007778:Lactobacillus / Q000187:drug effects* / Q000378:metabolism; D008826:Microbial Sensitivity Tests; D013752:Tetracycline / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D003470:Culture Media; D019344:Lactic Acid; D004917:Erythromycin; D004722:Endoribonucleases; C022543:ribonuclease T(2); D013752:Tetracycline