title: Mortality and morbidity in patients operated on for ruptured intracranial aneurysms.
abstract: It is generally agreed, mortality and morbidity rates, in patients operated on for ruptured intracranial aneurysm, strictly depend upon the state at admission. Nevertheless, a precise definition of surgical mortality is still not available. Even the term morbidity still remains rather controversial for the lack of accurate evaluation scales. The wide range of parameters, affecting the composition of sample and outcome of patients, such as age, blood at CT scan and atherosclerosis at angiography, makes harder a correct statistical analysis of mortality and morbidity. Moreover, the gap between bleeding and admission, the management and choice of treatment, the selection of unicentric or multicentric studies, the level of the hospital introduce even more striking bias errors. Recent papers reported concrete improvements obtained by means of both aggressive therapeutical behaviour and adequate intensive care management. Among factors, producing improvement of the overall outcome, have to be also reported the encouraging preliminary results supplied by the interventional neuroradiological techniques. However, the overall mortality rate of SAH remains high. Thus, a coded scheme for detection and prevention of risk factors significatively associated to mortality and outcome can be only worked out by employing an appropriate therapeutical behaviour and an adequate intensive care management. Furthermore, employment of feasible evaluation scales will be essential to point out the most accurate procedure for management and treatment of patients with intracranial ruptured aneurysm. We think CESE, developed by one of the authors, to be considered as an adequate method for the assessment of results at follow-up.
authors.affiliation: Institute of Neurosurgery, University of Milan, Milan, Italy.
authors.forename: R M
authors.initials: RM
authors.lastname: Villani
authors.forename: A
authors.initials: A
authors.lastname: De Santis
authors.forename: L
authors.initials: L
authors.lastname: Bello
authors.forename: G
authors.initials: G
authors.lastname: Ceccarelli
authors.forename: A
authors.initials: A
authors.lastname: Lanterna
authors.forename: D
authors.initials: D
authors.lastname: Spagnoli
mesh_terms: D017542:Aneurysm, Ruptured / Q000453:epidemiology / Q000401:mortality* / Q000601:surgery*; D006801:Humans; D002532:Intracranial Aneurysm / Q000453:epidemiology / Q000401:mortality* / Q000601:surgery*; D009017:Morbidity; D013345:Subarachnoid Hemorrhage / Q000401:mortality