Unusual presentation of multiple myeloma with "jumping translocation" involving 1q21. A case report and review of the literature.
We describe a case of multiple myeloma with unusual manifestations consisting of cutaneous xanthomatosis, temporal arteritis, retinal vasculitis with a complex karyotype, and a "jumping translocation" involving 1q21. The literature of cytogenetic studies of multiple myeloma and of jumping translocation is reviewed.
Keung
Y K
YK
Division of Oncology/Hematology, Cytogenetic Laboratory, Texas Tech University Health Sciences Center, Lubbock, USA.
Yung
C
C
Wong
J W
JW
Shah
F
F
Cobos
E
E
Tonk
V
V
D000368:Aged; D002878:Chromosomes, Human, Pair 1; D005260:Female; D006801:Humans; D007621:Karyotyping; D009101:Multiple Myeloma / Q000235:genetics*; D014178:Translocation, Genetic