title: Severe cytomegalovirus hepatitis in a pregnant woman treated with ganciclovir.
abstract: Severe cytomegalovirus (CMV) infection rarely occurs in immunocompetent patients, and the use of specific antiviral therapy in such patients has not been established. Here, we describe an unusual case of severe CMV hepatitis in an apparently immunocompetent pregnant woman treated with parenteral ganciclovir. The drug was well tolerated and progressive, improvement of liver function was observed after antiviral therapy. Aspects related with the use of ganciclovir in the immunocompetent host and in the pregnancy are discussed.
authors.affiliation: Hospital Nuestra Señora de la Candelaria, Tenerife, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Miguelez
authors.forename: A
authors.initials: A
authors.lastname: Gonzalez
authors.forename: F
authors.initials: F
authors.lastname: Perez
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000627:therapeutic use*; D003586:Cytomegalovirus Infections / Q000188:drug therapy*; D005260:Female; D015774:Ganciclovir / Q000627:therapeutic use*; D006525:Hepatitis, Viral, Human / Q000188:drug therapy*; D006801:Humans; D007121:Immunocompetence; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000188:drug therapy*; D011256:Pregnancy Outcome; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D015774:Ganciclovir