[Botulism. Summary based on six cases].
Botulism is a rare neuroparalytic disease caused by neurotoxins of Clostridium species. In Hungary it most commonly occurs as a foodborne illness with ocular and bulbar paralysis, muscle weakness and gastrointestinal symptoms. Six cases of botulism were observed by the authors, first in 1993 five members of a family, then in 1997 a patient with sporadic illness. The diagnosis was confirmed by toxin tests in addition to the symptoms and food history. Recognition of the epidemiologic associations proved very useful in the confirmation of outbreak-related cases. The illness was moderately serious at three patients and mild at two patients. One of the patients had a cirrhosis of the liver, and her status became critical because of the repeated bleeding from oesophagus varicose vein. The patient with sporadic illness had a serious gastric dilatation and palsy of bowels causing paralytic ileus at the start of the illness. The symptoms regressed slowly, roughly in three weeks, at all patients. Death did not happened. After the case reports the authors review the disease-microorganism, toxin, clinical entities, incidence, symptoms, diagnosis, differential-diagnosis, and finally the treatment.
Adorján
T
T
Felsö-Szabolcsi Kórház, Kisvárda, II. Belgyógyászati Osztály.
Farkas
M
M
Boros
L
L
Czeglédi
Z
Z
D000109:Acetylcholine / Q000378:metabolism*; D000293:Adolescent; D000328:Adult; D001906:Botulism / Q000150:complications / Q000453:epidemiology* / Q000378:metabolism / Q000382:microbiology; D003014:Clostridium botulinum; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D008297:Male; D009422:Nervous System Diseases / Q000209:etiology; D010243:Paralysis / Q000209:etiology
D000109:Acetylcholine