title: Real-time evaluation of the effectiveness of microwave coagulation therapy for hepatocellular carcinoma using color Doppler imaging.
abstract: Percutaneous microwave coagulation therapy (PMCT) is a new technique for the treatment of hepatocellular carcinoma (HCC). However, it is difficult to distinguish those lesions in which necrosis has been induced from the viable residual lesions during the procedure, because the margin of the tumor becomes unclear during PMCT. We determined the area of necrotic lesions during the procedure using color Doppler imaging. PMCT was performed on 10 patients (17 lesions) with recurrent HCC. The electrode of the microwave delivery system was moved around the tumor and the surrounding area until color mosaic images disappeared from the entire area of the tumor. The areas in which necrotic tissue was indicated by color Doppler imaging were later confirmed by other modalities such as angiography or contrast-enhanced computed tomography. This leads us to believe that real-time, effective evaluation of PMCT is possible with color Doppler imaging.
authors.affiliation: Department of Surgery, Iwakuni National Hospital, Yamaguchi, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Takeuchi
authors.forename: R
authors.initials: R
authors.lastname: Tamura
authors.forename: T
authors.initials: T
authors.lastname: Baba
authors.forename: T
authors.initials: T
authors.lastname: Kawashima
authors.forename: T
authors.initials: T
authors.lastname: Fukazawa
authors.forename: Y
authors.initials: Y
authors.lastname: Yunoki
authors.forename: K
authors.initials: K
authors.lastname: Tanakaya
authors.forename: Y
authors.initials: Y
authors.lastname: Yasui
authors.forename: E
authors.initials: E
authors.lastname: Konaga
mesh_terms: D000368:Aged; D000792:Angiography; D000818:Animals; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging / Q000601:surgery*; D002417:Cattle; D003199:Computer Systems; D004564:Electrocoagulation / Q000379:methods*; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008872:Microwaves / Q000627:therapeutic use*; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D018615:Ultrasonography, Doppler, Color