title: Postdural puncture headache in paediatric oncology patients.
abstract: OBJECTIVE
  Previous studies have not determined the correlation between dural puncture and postural headache in paediatric patients. Furthermore, no studies have evaluated the correlation between atypical headache and dural puncture in the paediatric population. Therefore, we prospectively analyzed the incidence of typical postdural puncture headache (PDPHA) and atypical headache in paediatric oncology patients following dural puncture.
  
  
  METHODS
  The study population consisted of 66 paediatric patients undergoing 128 consecutive procedures, including 99 lumbar punctures and 29 bone marrow aspirations without concomitant lumbar puncture. Patients were prospectively randomized into four groups: Group I, preteens (< 13 yr) undergoing lumbar puncture, Group II, adolescents (13-21 yr) undergoing lumbar puncture, Group III, preteens undergoing bone marrow aspiration, and Group IV, adolescents undergoing bone marrow aspiration. The presence and description of headache was documented immediately after dural puncture or bone marrow aspiration, and on post-procedure days # 1, 3 and 5 by personnel blinded to the type of procedure.
  
  
  RESULTS
  There was an increase in the incidence of headache (9.1%) after lumbar puncture in patients < 21 yr relative to patients undergoing bone marrow aspiration (P < 0.05). No difference was found between the incidence of typical PDPHA after dural puncture in preteens and adolescents. There was also no difference in the incidence of atypical headache after dural puncture or after bone marrow aspiration among preteens and adolescents.
  
  
  CONCLUSIONS
  Paediatric patients experience an increased incidence of typical postdural puncture headache after dural puncture compared with age-matched patients undergoing bone marrow aspiration only. Atypical headache is relatively common in the paediatric population after dural puncture or bone marrow aspiration.
authors.affiliation: Department of Anesthesiology, Medical University of South Carolina, Charleston 29425-2207, USA. burtn@musc.edu
authors.forename: N
authors.initials: N
authors.lastname: Burt
authors.forename: B H
authors.initials: BH
authors.lastname: Dorman
authors.forename: S T
authors.initials: ST
authors.lastname: Reeves
authors.forename: P F
authors.initials: PF
authors.lastname: Rust
authors.forename: M L
authors.initials: ML
authors.lastname: Pinosky
authors.forename: M R
authors.initials: MR
authors.lastname: Abboud
authors.forename: J C
authors.initials: JC
authors.lastname: Barredo
authors.forename: J H
authors.initials: JH
authors.lastname: Laver
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D006261:Headache / Q000209:etiology*; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000601:surgery; D011446:Prospective Studies; D013129:Spinal Puncture / Q000009:adverse effects*