Recognition memory for object form and object location: an event-related potential study.
In this study, the processes associated with retrieving object forms and object locations from working memory were examined with the use of simultaneously recorded event-related potential (ERP) activity. Subjects memorized object forms and their spatial locations and made either object-based or location-based recognition judgments. In Experiment 1, recognition performance was higher for object locations than for object forms. Old responses evoked more positive-going ERP activity between 0.3 and 1.8 sec poststimulus than did new responses. The topographic distribution of these old/new effects in the P300 time interval was task specific, with object-based recognition judgments being associated with anteriorly focused effects and location-based judgments with posteriorly focused effects. Late old/new effects were dominant at right frontal recordings. Using an interference paradigm, it was shown in Experiment 2 that visual representations were used to rehearse both object forms and object locations in working memory. The results of Experiment 3 indicated that the observed differential topographic distributions of the old/new effects in the P300 time interval are unlikely to reflect differences between easy and difficult recognition judgments. More specific effects were obtained for a subgroup of subjects for which the processing characteristics during location-based judgments presumably were similar to those in Experiment 1. These data, together with those from Experiment 1, indicate that different brain areas are engaged in retrieving object forms and object locations from working memory. Further analyses support the view that retrieval of object forms relies on conceptual semantic representation, whereas retrieving object locations is based on structural representations of spatial information. The effects in the later time intervals may play a functional role in post-retrieval processing, such as recollecting information from the study episode or other processes operating on the products of the retrieval process, and presumably are mediated by right frontal cortical areas. The results support the view of functionally dissociable object and spatial visual working memory systems.
Mecklinger
A
A
Max-Planck-Institute of Cognitive Neuroscience, Leipzig, Germany. meckling@cns.mpg.de
Meinshausen
R M
RM
D000328:Adult; D000704:Analysis of Variance; D001931:Brain Mapping; D002540:Cerebral Cortex / Q000502:physiology; D003071:Cognition / Q000502:physiology*; D018913:Event-Related Potentials, P300; D005260:Female; D005556:Form Perception / Q000502:physiology*; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology*; D011939:Mental Recall; D008959:Models, Neurological; D009949:Orientation; D010364:Pattern Recognition, Visual / Q000502:physiology; D011930:Reaction Time; D012016:Reference Values; D013028:Space Perception / Q000502:physiology*