In vivo gradient echo microimaging of rodent spinal cord at 7 T.
An optimization scheme was developed for gradient echo imaging using a half-birdcage RF coil at 7 T to obtain maximal contrast between gray and white matter in the spinal cord of rodents. This optimization was combined with microimaging techniques to obtain in vivo pixel sizes of 78 x 78 x 700 microm. These techniques can be implemented in an in vivo study to investigate the myelin structure within the white matter of the rodent spinal cord.
Meyerand
M E
ME
Department of Radiology, Biomedical NMR Research Lab, Dartmouth-Hitchcock Medical Center, Hanover, New Hampshire 03755, USA.
Cremillieux
Y
Y
Wadghiri
Y Z
YZ
Azzawi
A
A
Hoopes
P J
PJ
Dunn
J F
JF
D000818:Animals; D007089:Image Enhancement / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D051381:Rats; D017207:Rats, Sprague-Dawley; D012680:Sensitivity and Specificity; D013116:Spinal Cord / Q000033:anatomy & histology*