title: The call of the sirens: ethically navigating the sea of nonvalidated therapies.
abstract: Medical research and innovation are vital to the advancement of medicine and, ultimately, benefit society and individual patients. However, the ethical principles of beneficence, respect for persons, and justice must guide the development and implementation of new practices. Ethical codes governing clinical practice and research already warn practitioners to avoid the use of nonvalidated practices outside of controlled clinical trials. Nonetheless, lack of compliance with these codes places many patients at risk for harm. Ophthalmologists, as well as all physicians, must recommit themselves to these ethical principles and codes and establish more vigorous peer-review methods to protect patients from nonvalidated practices that are implemented without a scientific basis.
authors.affiliation: Bascom Palmer Eye Institute, University of Miami, School of Medicine, FL, USA.
authors.forename: M R
authors.initials: MR
authors.lastname: Grimmett
authors.forename: D P
authors.initials: DP
authors.lastname: Sulmasy
mesh_terms: D002986:Clinical Trials as Topic; D000529:Complementary Therapies; D004992:Ethics, Medical; D006801:Humans; D007258:Informed Consent; D008490:Medical Informatics; D013508:Ophthalmologic Surgical Procedures / Q000592:standards