title: [Incidence of tumors in renal transplant patients. Is there a changing tumor pattern in these patients?].
abstract: OBJECTIVE
  To analyze the incidence of tumors in renal graft recipients, the course, treatment and its effect on the graft and patient.
  
  
  METHODS
  We conducted a retrospective and prospective study on 477 renal transplants performed at our hospital from 1980 to 1996. The tumor type, course and possible tumor-related factors (immunosuppression, age, sex, graft rejection, virus) were analyzed.
  
  
  RESULTS
  57 tumors were found; 41 patients had at least one tumor. The most common were skin, renal and lung cancer. Age, sex and immunosuppression were found to be tumor-related factors in renal transplant recipients.
  
  
  CONCLUSIONS
  Patients undergoing renal transplantation are at a higher risk for developing a tumor, above all in the older male patients. A relationship was found for immunosuppression, the number of drugs received and the number of rejection episodes. Furthermore, the tumor pattern in these patients is different from the usual pattern.
authors.affiliation: Cátedra y Servicio de Urología, Servicio de Nefrología, Hospital Clínico San Carlos, Madrid, España.
authors.forename: J F
authors.initials: JF
authors.lastname: Hermida Gutiérrez
authors.forename: J
authors.initials: J
authors.lastname: Moreno Sierra
authors.forename: J
authors.initials: J
authors.lastname: Blázquez Izquierdo
authors.forename: A
authors.initials: A
authors.lastname: Gómez Vegas
authors.forename: A
authors.initials: A
authors.lastname: Silmi Moyano
authors.forename: D
authors.initials: D
authors.lastname: Prats Sánchez
authors.forename: C
authors.initials: C
authors.lastname: Fernández Pérez
authors.forename: L
authors.initials: L
authors.lastname: Resel Estévez
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D006084:Graft Rejection / Q000517:prevention & control; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D015994:Incidence; D016030:Kidney Transplantation / Q000276:immunology / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000453:epidemiology* / Q000276:immunology; D011446:Prospective Studies; D012189:Retrospective Studies; D012737:Sex Factors; D013030:Spain / Q000453:epidemiology
chemical_list: D007166:Immunosuppressive Agents