Pharmacotherapy of social anxiety disorder.
Antidepressants and high-potency benzodiazepines have been used successfully to treat patients with social anxiety disorder. This review considers the efficacy of irreversible and reversible inhibitors of monoamine oxidase, selective serotonin reuptake inhibitors, high-potency benzodiazepines, and beta-blockers and presents the response rates for each of these classes. Aspects of the social anxiety syndrome that are sensitive to drug treatment are discussed, and the data relating to relapse following treatment discontinuation are presented. Predictors for negative treatment outcome following completion of acute treatment trials are reviewed.
Davidson
J R
JR
Department of Psychiatry and Behavioral Science, Duke University Medical Center, Durham, North Carolina 27710, USA.
D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D001569:Benzodiazepines / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D008996:Monoamine Oxidase Inhibitors / Q000627:therapeutic use*; D015337:Multicenter Studies as Topic; D010698:Phobic Disorders / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D011379:Prognosis; D012008:Recurrence; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D016896:Treatment Outcome
D000319:Adrenergic beta-Antagonists; D001569:Benzodiazepines; D008996:Monoamine Oxidase Inhibitors; D017367:Selective Serotonin Reuptake Inhibitors