Triplet pregnancy complicated by a gradual decline in antithrombin-III activity and HELLP syndrome: a case report.
We prospectively evaluated the antenatal changes in antithrombin-III (AT-III) activity and liver enzymes in a woman with a triplet pregnancy. A gradual decline in AT-III activity occurred in the absence of clinical signs of preeclampsia and preceded the onset of the typical HELLP syndrome in this patient. Monitoring of AT-III activity might help to avoid the development of severe HELLP syndrome.
Izumi
A
A
Department of Obstetrics and Gynecology, Jichi Medical School, Tochigi, Japan.
Minakami
H
H
Matsubara
S
S
Sato
I
I
D000328:Adult; D000410:Alanine Transaminase / Q000097:blood; D000990:Antithrombin III / Q000378:metabolism* / Q000494:pharmacology; D002585:Cesarean Section; D005260:Female; D005307:Fertilization in Vitro; D017359:HELLP Syndrome / Q000097:blood* / Q000201:enzymology / Q000628:therapy; D006242:Haptoglobins / Q000032:analysis; D006801:Humans; D007770:L-Lactate Dehydrogenase / Q000097:blood; D008099:Liver / Q000201:enzymology; D008297:Male; D010976:Platelet Count; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood* / Q000201:enzymology; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple / Q000097:blood / Q000378:metabolism / Q000502:physiology*; D011446:Prospective Studies; D014310:Triplets; D014527:Uric Acid / Q000097:blood
D006242:Haptoglobins; D014527:Uric Acid; D000990:Antithrombin III; D007770:L-Lactate Dehydrogenase; D000410:Alanine Transaminase