title: Cloning, characterisation and expression of the apolipoprotein A-I gene in the sea bream (Sparus aurata).
abstract: A full length cDNA clone representing apolipoprotein A-I was isolated from a sea bream (Sparus aurata) liver library. The clone encodes a 261 amino acid protein which shows highest amino acid identity (38%) with salmon apolipoprotein A-I. Northern blot analysis showed strong expression of a 1.4 kb transcript in liver with lower expression in intestine. Expression of apolipoprotein A-I in intestine was markedly reduced by treatment with triiodothyronine (T3).
authors.affiliation: School of Molecular and Medical Biosciences, University of Wales, P. O. Box 911, Cardiff CF1 3US, UK.
authors.forename: L
authors.initials: L
authors.lastname: Llewellyn
authors.forename: V P
authors.initials: VP
authors.lastname: Ramsurn
authors.forename: T
authors.initials: T
authors.lastname: Wigham
authors.forename: G E
authors.initials: GE
authors.lastname: Sweeney
authors.forename: D M
authors.initials: DM
authors.lastname: Power
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D016632:Apolipoprotein A-I / Q000096:biosynthesis / Q000737:chemistry / Q000235:genetics*; D001483:Base Sequence; D002645:Chickens / Q000235:genetics; D003001:Cloning, Molecular; D018076:DNA, Complementary; D006801:Humans; D008969:Molecular Sequence Data; D010473:Perciformes / Q000235:genetics*; D014176:Protein Biosynthesis; D011817:Rabbits; D011994:Recombinant Proteins / Q000096:biosynthesis / Q000737:chemistry; D012156:Reticulocytes / Q000378:metabolism; D012474:Salmon / Q000235:genetics; D016415:Sequence Alignment; D017386:Sequence Homology, Amino Acid; D014337:Trout / Q000235:genetics
chemical_list: D016632:Apolipoprotein A-I; D018076:DNA, Complementary; D011994:Recombinant Proteins