title: Mortality from lower respiratory infection in nursing home residents. A pilot prospective community-based study.
abstract: BACKGROUND
  Lower respiratory infections (LRI) are an important cause of morbidity, mortality, and hospitalization of nursing home residents, yet treatment recommendations have primarily been based on the minority who are hospitalized. We sought to prospectively evaluate risk factors for mortality from LRI in community nursing home residents.
  
  
  METHODS
  We studied residents of 10 central Missouri nursing homes (910 beds) from January 1994 to September 1994. Attending physicians authorized nurse evaluations of ill residents who showed symptoms of an LRI. Those residents who met the study definition of LRI received a more detailed assessment and follow ups at 30 and 90 days.
  
  
  RESULTS
  The 231 evaluations identified 141 LRIs in 121 individuals. Sixteen (11%) residents died within 30 days of evaluation. The most important univariate predictor of 30-day mortality was severe activities of daily living (ADL) dependency (relative risk = 8.8, 95% confidence interval, 2.55-30.1). Several other clinical and laboratory findings were also significant predictors. In multivariable logistic regression, ADL dependency, respiratory rate, and pneumonia on chest radiograph independently predicted mortality; the model showed good discriminating ability (c = .83).
  
  
  CONCLUSIONS
  For nursing home residents with LRI, ADL dependency is an important mortality predictor. Further research with a larger sample should lead to a useful prediction rule for outcome from nursing home-acquired LRI.
authors.affiliation: Department of Family and Community Medicine, Sinclair School of Nursing, University of Missouri-Columbia 65212, USA. MehrD@health.missouri.edu
authors.forename: D R
authors.initials: DR
authors.lastname: Mehr
authors.forename: S C
authors.initials: SC
authors.lastname: Zweig
authors.forename: R L
authors.initials: RL
authors.lastname: Kruse
authors.forename: L
authors.initials: L
authors.lastname: Popejoy
authors.forename: D
authors.initials: D
authors.lastname: Horman
authors.forename: D
authors.initials: D
authors.lastname: Willis
authors.forename: M E
authors.initials: ME
authors.lastname: Doyle
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D005544:Forecasting; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D008923:Missouri / Q000453:epidemiology; D009735:Nursing Homes / Q000706:statistics & numerical data*; D010865:Pilot Projects; D011014:Pneumonia / Q000401:mortality / Q000503:physiopathology; D011446:Prospective Studies; D012119:Respiration; D012141:Respiratory Tract Infections / Q000209:etiology / Q000401:mortality* / Q000503:physiopathology; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents