No evidence for linkage of a novel CA repeat polymorphism for apoptosis antigen 1 (APO-1 or fas) with type I diabetes in a Caucasian population.
A novel microsatellite marker was found within 48.5 kb of the Fas gene. The observed heterozygosity in 160 healthy unrelated controls was 0.78. There was no evidence of linkage to type I diabetes mellitus in 120 diabetic children using the transmission disequilibrium test.
Sangthongpitag
K
K
Garvan Institute of Medical Research, St. Vincent's Hospital, University of New South Wales, Sydney, Australia.
Moore
K R
KR
Lapsys
N M
NM
Bao
F
F
Babu
S R
SR
Fain
P R
PR
Verge
C F
CF
D001483:Base Sequence; D002648:Child; D017931:DNA Primers; D003922:Diabetes Mellitus, Type 1 / Q000235:genetics*; D005787:Gene Frequency; D008040:Genetic Linkage; D006579:Heterozygote; D006801:Humans; D018895:Microsatellite Repeats; D011110:Polymorphism, Genetic; D044465:White People / Q000235:genetics*; D019014:fas Receptor / Q000235:genetics*
D017931:DNA Primers; D019014:fas Receptor