title: The hypothesis of an ambient level of acetylcholine in the central nervous system.
abstract: Recent ultrastructural data demonstrate the largely asynaptic character of the cholinergic innervation in many regions of adult rat brain. These data favour the hypothesis of a diffuse transmission/modulation by acetylcholine in the CNS and, by way of consequence, that of a persistent, low level of acetylcholine in the extracellular space.
authors.affiliation: Département de pathologie, Faculté de médecine, Université de Montréal, Québec, Canada.
authors.forename: L
authors.initials: L
authors.lastname: Descarries
mesh_terms: D000109:Acetylcholine / Q000378:metabolism*; D000818:Animals; D001481:Basal Metabolism; D001921:Brain / Q000378:metabolism*; D017729:Presynaptic Terminals / Q000378:metabolism*; D051381:Rats; D009435:Synaptic Transmission / Q000502:physiology
chemical_list: D000109:Acetylcholine