[Bronchial asthma due to Stronger Neo-Minophagen C].
A 24-year-old woman who visited our hospital because of urticaria had a bronchial asthma attack about 5 min. after receiving Stronger Neo-Minophagen C (SNMC) intravenously. A skin test for SNMC and its components (glycyrrhizin, L-cystein, aminoacetic acid, and sodium sulfite) was positive for SNMC and borderline for sodium sulfite after 15 min. A skin test for mixtures of L-cystein and sodium sulfite was also positive. Inhalation provocation tests for SNMC and mixtures of L-cystein and sodium sulfite were positive after 5 min. An inhalation provocation test for sulpyrin was also positive. The patient's bronchial asthma attack was ascribed to SNMC. Type I allergy to mixtures of L-cystein and sodium sulfite was the suspected cause.
Nakatsumi
Y
Y
Department of Respiratory Medicine, Kanazawa Municipal Hospital, Japan.
Abe
T
T
Nomura
G
G
Fujimura
M
M
Matsuda
T
T
D000328:Adult; D000893:Anti-Inflammatory Agents / Q000009:adverse effects*; D001249:Asthma / Q000139:chemically induced*; D003545:Cysteine / Q000009:adverse effects*; D004338:Drug Combinations; D005260:Female; D005998:Glycine / Q000009:adverse effects*; D006034:Glycyrrhetinic Acid / Q000009:adverse effects / Q000031:analogs & derivatives*; D006801:Humans; D013256:Steroids
D000893:Anti-Inflammatory Agents; D004338:Drug Combinations; D013256:Steroids; C083319:stronger neominophagen C; D003545:Cysteine; D006034:Glycyrrhetinic Acid; D005998:Glycine