Risk factors in the pathogenesis of coronary artery disease.
In men, plaque rupture is strongly correlated with total cholesterol, and smoking is a predictor of acute thrombosis. In women younger than 50, plaque erosion correlates with smoking, whereas in women older than 50, thrombosis is secondary to plaque rupture and correlates with total cholesterol.
Virmani
R
R
Armed Forces Institute of Pathology, Department of Cardiovascular Pathology, Washington, DC 20306-6000, USA.
Farb
A
A
Burke
A P
AP
D000367:Age Factors; D002784:Cholesterol / Q000097:blood; D003327:Coronary Disease / Q000097:blood / Q000209:etiology* / Q000473:pathology*; D006801:Humans; D012307:Risk Factors; D012737:Sex Factors; D012907:Smoking / Q000009:adverse effects
D002784:Cholesterol