title: Lhermitte-Duclos disease: first report in Taiwan.
abstract: We report a case of Lhermitte-Duclos disease (dysplastic gangliocytoma of the cerebellum), an uncommon disorder of uncertain pathogenesis characterized by disarrangement of the normal cerebellar laminar cytoarchitecture. A 40-year-old man was admitted because of vomiting and syncope of a few days' duration, and a 2-month history of intermittent headaches and unsteady gait. A computed tomographic scan of the patient's head showed obstructive hydrocephalus due to displacement of the fourth ventricle by a large, nonenhancing cerebellar mass. The magnetic resonance images of the brain also revealed a space-occupying lesion within the right cerebellum with unusual septation. After surgery, the histologic examination confirmed the diagnosis of Lhermitte-Duclos disease. This is the first report of Lhermitte-Duclos disease in Taiwan.
authors.affiliation: Department of Neurology, Chang Gung Memorial Hospital, Taipei, Taiwan.
authors.forename: J D
authors.initials: JD
authors.lastname: Lee
authors.forename: Y S
authors.initials: YS
authors.lastname: Ho
authors.forename: S T
authors.initials: ST
authors.lastname: Chen
authors.forename: T K
authors.initials: TK
authors.lastname: Lin
authors.forename: L S
authors.initials: LS
authors.lastname: Ro
authors.forename: T H
authors.initials: TH
authors.lastname: Lee
mesh_terms: D000328:Adult; D002528:Cerebellar Neoplasms / Q000175:diagnosis* / Q000601:surgery; D005729:Ganglioneuroma / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008297:Male