Nonsteroidal anti-inflammatory drug use in adolescence.
Nonsteroidal anti-inflammatory drugs (NSAIDs) have been recently released as over-the-counter drugs making them more widely available to the general public. We present five cases of adolescents with complications, including acute and chronic renal failure, related to the use of NSAIDs. Risk factors for NSAID nephrotoxicity include chronic illness, dehydration, ethanol and use of other medications. Adolescents should be educated about the risks and prevention of NSAID toxicity.
Nakahura
T
T
Department of Pediatrics, UCSD School of Medicine, La Jolla, California 92093, USA.
Griswold
W
W
Lemire
J
J
Mendoza
S
S
Reznik
V
V
D058186:Acute Kidney Injury / Q000139:chemically induced*; D000293:Adolescent; D000295:Adolescent Medicine; D000328:Adult; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007668:Kidney / Q000187:drug effects; D007676:Kidney Failure, Chronic / Q000139:chemically induced*; D008297:Male; D010353:Patient Education as Topic; D012307:Risk Factors
D000894:Anti-Inflammatory Agents, Non-Steroidal