[Comparative study of composite danshen droplet pills and sordi in treatment of patients with chronic stable angina].
OBJECTIVE
To observe the effect of Composite Dansen Droplet Pills (CDDP) in treating chronic stable angina.


METHODS
The effect of oral CDDP and Sordi were compared with those of placebo in 64 patients with chronic stable angina. Patients performed symptom limited multistage, supine bicycle ergometric exercise, while undergoing non-imaging radionuclide angiocardiographic examination after 8 week periods treatment of 10-15 pills, three times daily, 10-15 mg Sordi three times daily, and placebo. All drugs were given double blind and randomly. Adverse effects that occurred during drug treatment were minor and generally well tolerated.


RESULTS
CDDP not only appeared to be more effective than Sordi in increasing exercise duration and delaying time of onset of exercise angina or peak effort, but also seems to be superior to Sordi in improving either the stress-induced myocardial ischemia or the exercise left ventricular systolic function.


CONCLUSIONS
CDDP is a more effective drug in treating chronic stable angina.
Shi
Y H
YH
Fourth Affiliated Hospital of Hebei Medical College, Shijiazhuang.
D000328:Adult; D000787:Angina Pectoris / Q000188:drug therapy*; D004338:Drug Combinations; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D007548:Isosorbide Dinitrate / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010618:Phenanthrolines / Q000627:therapeutic use*; D010936:Plant Extracts; D027561:Salvia miltiorrhiza; D014665:Vasodilator Agents / Q000627:therapeutic use
D004338:Drug Combinations; D004365:Drugs, Chinese Herbal; D010618:Phenanthrolines; D010936:Plant Extracts; D014665:Vasodilator Agents; C028972:dan-shen root extract; D007548:Isosorbide Dinitrate