title: Pyrexia, anaemia and acute renal failure secondary to omeprazole.
abstract: We present the case of a 77-year-old woman who initially presented with pyrexia of unknown origin, anaemia and mild renal impairment. When her omeprazole was stopped she improved rapidly. When omeprazole was re-started she developed fever and acute renal failure, which again settled quickly on discontinuation of omeprazole. This case demonstrates how drugs can cause severe multisystem disorders that may appear to be infective or inflammatory.
authors.affiliation: Department of Medicine, Horton General Hospital, Banbury, Oxfordshire, UK.
authors.forename: M J
authors.initials: MJ
authors.lastname: Landray
authors.forename: T
authors.initials: T
authors.lastname: Ringrose
authors.forename: R E
authors.initials: RE
authors.lastname: Ferner
authors.forename: I R
authors.initials: IR
authors.lastname: Arnold
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced*; D000368:Aged; D000740:Anemia / Q000139:chemically induced*; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000009:adverse effects*; D001799:Blood Sedimentation; D004415:Dyspepsia / Q000188:drug therapy; D005260:Female; D005334:Fever / Q000139:chemically induced*; D006801:Humans; D009853:Omeprazole / Q000009:adverse effects*; D011239:Prednisolone / Q000627:therapeutic use; D012008:Recurrence
chemical_list: D000893:Anti-Inflammatory Agents; D000897:Anti-Ulcer Agents; D011239:Prednisolone; D009853:Omeprazole