[Erythermalgias].
Erythermalgia is an unfrequent disorder characterised by recurrent, red, warm and painful extremities. Classification of erythermalgia is clinical: primary erythermalgia usually starting during childhood; erythromelalgia secondary to myeloproliferative disorders (especially thrombocytosis or polycythaemia vera); erythermalgia seconndary to drugs or vasculitis. Intravascular platelet activation and aggregation with plugging of the arterioles has been suggested as the mechanism of secondary erythromelalgia; aspirin is an effective treatment. Conversely, as yet unelucidated pathophysiologic events underlie primary erythermalgia, which usually fails to respond to aspirin.
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Département de médecine interne, CHU Rouen-Boisguillaume.
D003937:Diagnosis, Differential; D004916:Erythromelalgia / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006801:Humans