[Pre-implantation genetic diagnosis: indications, techniques, and results].
The combination of the technique of In Vitro Fertilization (IVF) and molecular genetics has led to the development of Preimplantation Genetic Diagnosis (PGD). Oocyte and embryo biopsy, Fluorescent in situ Hybridization (FISH) and Polymerase Chain Reaction (PCR) allow diagnostic procedures in couples with high risk and also certain IVF couples. We present a review of PGD indications, techniques and results.
Veiga
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A
Dpt. Obst. Gynec., Institut Universitari Dexeus, Barcelona, Spain.
Boada
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M
Barri
P N
PN
D001706:Biopsy / Q000379:methods; D005260:Female; D030342:Genetic Diseases, Inborn / Q000175:diagnosis*; D008040:Genetic Linkage; D006579:Heterozygote; D006801:Humans; D017404:In Situ Hybridization, Fluorescence; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D019836:Preimplantation Diagnosis / Q000379:methods*; D012729:Sex Chromosome Aberrations / Q000175:diagnosis; D014960:X Chromosome