[Comparative analysis of electroencephalographic effects of trimetidon and phenazepam on the brain function during emotional stress in cats].
Trimetidon decreased the high-frequency spectral power and enhanced theta-, alpha-band frequencies in recordings from parietal and visual areas as well as beta-1-band frequencies recorded from the sensomotor area during emotional stress in cats. Phenazepam desynchronised the EEG. The latter state alternated with sedation-associated spindles and slow waves. The trimetidon effect was similar to that of 1.4-benzodiazepines.
Kiroĭ
V N
VN
Rostov State University, Russia.
Belova
E I
EI
Gusach
Iu I
IuI
D000818:Animals; D014151:Anti-Anxiety Agents / Q000494:pharmacology*; D001569:Benzodiazepines; D002415:Cats; D004569:Electroencephalography / Q000187:drug effects*; D019579:Neocortex / Q000187:drug effects* / Q000502:physiology; D011619:Psychotropic Drugs / Q000494:pharmacology*; D011743:Pyrimidines / Q000494:pharmacology*; D013315:Stress, Psychological / Q000503:physiopathology*
D014151:Anti-Anxiety Agents; D011619:Psychotropic Drugs; D011743:Pyrimidines; C096687:trimetidon; D001569:Benzodiazepines; C017928:phenazepam