Nutritional modulation of gut inflammation.
Nutritional therapy is an important component of the management of gastrointestinal inflammation, which disrupts the gut mucosal barrier leading to sepsis, SIRS and MODS. Future studies will be needed to define the role of specific nutrients in enhancing mucosal barrier function and supporting general immune function, and how this affects morbidity and mortality of critically-ill patients.
Rowlands
B J
BJ
Queens Medical Centre, Nottingham, UK. bjr.surgery@nottingham.ac.uk
Gardiner
K R
KR
D000818:Animals; D018988:Bacterial Translocation; D004750:Enteral Nutrition; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000150:complications / Q000178:diet therapy*; D007413:Intestinal Mucosa / Q000382:microbiology / Q000503:physiopathology; D009102:Multiple Organ Failure / Q000209:etiology / Q000503:physiopathology; D018805:Sepsis / Q000209:etiology / Q000503:physiopathology; D018746:Systemic Inflammatory Response Syndrome / Q000209:etiology / Q000503:physiopathology