title: Detection of enteroviral sequence in endomyocardial tissues from patients with cardiac diseases in northern Brazil.
abstract: In the present report we describe the results from a pilot study aimed at detecting enterovirus sequence in cardiac tissues, obtained through endomyocardial biopsies, from patients suffering from cardiac diseases in the Amazon region. Six samples that were collected from three patients were analysed by RT-PCR showing 3 positive and 3 negative results. These preliminary findings suggest the participation of enteroviruses in the etiology of cardiac diseases, mainly myocarditis, and warrant further and broader local studies on this subject.
authors.affiliation: Instituto Evandro Chagas, Fundação Nacional de Saúde, Belém, Brasil.
authors.forename: M de L
authors.initials: Mde L
authors.lastname: Gomes
authors.forename: H
authors.initials: H
authors.lastname: Kopecka
authors.forename: A G
authors.initials: AG
authors.lastname: Ferreira Júnior
authors.forename: S M
authors.initials: SM
authors.lastname: Ferreira
authors.forename: L A
authors.initials: LA
authors.lastname: Maneschy
authors.forename: A C
authors.initials: AC
authors.lastname: Linhares
mesh_terms: D000328:Adult; D000368:Aged; D001938:Brazil; D004279:DNA, Viral / Q000032:analysis; D004770:Enterovirus / Q000235:genetics / Q000302:isolation & purification*; D004769:Enterovirus Infections / Q000150:complications* / Q000473:pathology; D005260:Female; D006321:Heart / Q000821:virology*; D006331:Heart Diseases / Q000209:etiology / Q000473:pathology / Q000821:virology*; D006801:Humans; D008297:Male; D009206:Myocardium / Q000473:pathology*; D016133:Polymerase Chain Reaction
chemical_list: D004279:DNA, Viral