Comment on the cylindrical capacitor electrospray interface.
Wang and Hackett have recently proposed (Anal. Chem. 1998, 70, 205-212) a new electrospray interface described as a "concentric cylindrical capacitor". Excellent spectra were obtained, especially in the negative ion mode, with lipid A, a 15-mer oligonucleotide, and a series of proteins. We find that similar results can be obtained merely by ensuring a direct electrical contact between the analyte inside a fused-silica capillary and the high-voltage supply. No capacitor effect need be invoked.
König
S
S
Fales
H M
HM
Haegele
K D
KD
D008050:Lipid A / Q000737:chemistry; D013058:Mass Spectrometry / Q000295:instrumentation*; D009841:Oligonucleotides / Q000737:chemistry; D011506:Proteins / Q000737:chemistry; D012822:Silicon Dioxide
D008050:Lipid A; D009841:Oligonucleotides; D011506:Proteins; D012822:Silicon Dioxide