The effects of early and sustained intervention on the long-term morbidity of schizophrenia.
By examining the literature concerning early intervention with antipsychotic medications, and how it affects long-term morbidity, this article will review the concept that early intervention with antipsychotic medications improves the long-term course of schizophrenia. It also looks at the potential long-term effects of discontinuing antipsychotic medications early in the course of schizophrenia. It appears that early intervention with antipsychotic medications decreases some of the long-term morbidity associated with schizophrenia. Some of the implications of this finding are discussed in the context of both clinical practice and clinical research.
Wyatt
R J
RJ
Neuropsychiatry Branch NIMH-NIH Neuroscience Center at St Elizabeths, Washington, D.C. 20032, USA.
Henter
I D
ID
D014150:Antipsychotic Agents / Q000627:therapeutic use*; D018450:Disease Progression; D006801:Humans; D012559:Schizophrenia / Q000188:drug therapy*; D013997:Time Factors
D014150:Antipsychotic Agents