Comparison of ceftriaxone, amikacin, and ciprofloxacin in treatment of experimental Yersinia enterocolitica O9 infection in mice.
Ceftriaxone and ciprofloxacin were effective in the treatment of Yersinia enterocolitica O9 intestinal infection in mice. Amikacin was less effective. The impact of these drugs on indigenous bacteria from the intestinal microbiota was studied.
Jiménez-Valera
M
M
Department of Microbiology, Faculty of Pharmacy, University of Granada, Granada, Spain.
Gonzalez-Torres
C
C
Moreno
E
E
Ruiz-Bravo
A
A
D000583:Amikacin / Q000627:therapeutic use*; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002443:Ceftriaxone / Q000627:therapeutic use*; D002939:Ciprofloxacin / Q000627:therapeutic use*; D005243:Feces / Q000382:microbiology; D005260:Female; D007410:Intestinal Diseases / Q000188:drug therapy*; D051379:Mice; D008807:Mice, Inbred BALB C; D015009:Yersinia Infections / Q000188:drug therapy*; D015008:Yersinia enterocolitica
D000900:Anti-Bacterial Agents; D002939:Ciprofloxacin; D002443:Ceftriaxone; D000583:Amikacin