Enterotoxigenic Clostridium perfringens type A necrotic enteritis in a foal.
A Thoroughbred-Quarter Horse crossbred foal developed hemorrhagic enteritis and died < 48 hours after birth. Gross and histologic findings were suggestive of Clostridium perfringens type C infection, and large numbers of C perfringens were isolated from intestinal contents. However, genotyping of isolates indicated that they were enterotoxigenic C perfringens type A, and isolates were found to produce C perfringens enterotoxin in vitro. This case suggests that enterotoxigenic C perfringens type A may cause enteric disease in horses.
Bueschel
D
D
Department of Veterinary Science and Microbiology, University of Arizona, Tucson 85721, USA.
Walker
R
R
Woods
L
L
Kokai-Kun
J
J
McClane
B
B
Songer
J G
JG
D000818:Animals; D000831:Animals, Newborn; D015153:Blotting, Western / Q000662:veterinary; D003015:Clostridium Infections / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D003016:Clostridium perfringens / Q000145:classification* / Q000235:genetics / Q000378:metabolism; D004751:Enteritis / Q000382:microbiology / Q000473:pathology / Q000662:veterinary*; D004768:Enterotoxins / Q000032:analysis / Q000096:biosynthesis* / Q000235:genetics; D005838:Genotype; D006734:Horse Diseases / Q000382:microbiology* / Q000473:pathology; D006736:Horses; D007422:Intestines / Q000737:chemistry / Q000382:microbiology / Q000473:pathology; D009336:Necrosis
D004768:Enterotoxins; C035598:enterotoxin, Clostridium