[Changes in biochemical parameters of erythrocytes in workers engaged in pyromellitic dianhydride production].
The article presents data of research concerning levels of adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP), activity of Na, K- and Ca, Mg-dependent adenosine triphosphatases, glucose-6-phosphate dehydrogenase, concentrations of sodium, potassium, calcium, magnesium and phosphorus in workers contacting some chemicals (pseudocumene, durene, dioxane-1,4, pyromellitic dianhydride, etc.) at work. All examinees were divided into 3 groups in consideration with intensity of chemical exposure: group 1--workers free of the exposure, group 2--workers exposed to the chemicals 2-3 times a week, group 3--workers exposed to the chemicals constantly at work during 3-5 years. Healthy individuals having no occupational exposure to the chemicals formed a reference group. Members of the groups 2 and 3 demonstrated lower levels of ATP, potassium, magnesium, calcium, decreased activity of Ca, Mg-dependent adenosinetriphosphatase and higher levels of ADP, AMP, Na, P and increased activity of Na, K-dependent adenosinetriphosphatase and glucose-6-phosphate dehydrogenase.
Shakirov
D F
DF
Kamilov
F Kh
FKh
Farkhutdinov
R R
RR
Likhovskikh
V A
VA
D000244:Adenosine Diphosphate / Q000097:blood; D000249:Adenosine Monophosphate / Q000097:blood; D000255:Adenosine Triphosphate / Q000097:blood; D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D001555:Benzene Derivatives / Q000009:adverse effects*; D004573:Electrolytes / Q000097:blood; D004912:Erythrocytes / Q000187:drug effects* / Q000378:metabolism; D006801:Humans; D009784:Occupational Diseases / Q000175:diagnosis*; D013997:Time Factors
D000395:Air Pollutants, Occupational; D001555:Benzene Derivatives; D004573:Electrolytes; C023973:durene; C010313:pseudocumene; D000249:Adenosine Monophosphate; D000244:Adenosine Diphosphate; D000255:Adenosine Triphosphate
Izmeneiia biokhimicheskikh pokazateleĭ éritrotsitov u rabochikh proizvodstva piromellitovogo diangidrida.