title: Cytomegalovirus iritis.
abstract: We describe a case of focal cytomegalovirus iritis in a patient with acquired immunodeficiency syndrome (AIDS) who had CMV retinitis. The autopsy showed histologic evidence of focal iritis in the left eye. This iritis was characterized by infiltration of acute inflammatory cells mixed with cytomegalic cells, which was confirmed by CMV-specific immunohistochemical staining. The case suggested that cytomegalovirus could be a direct causative agent of infectious iritis in AIDS patients.
authors.affiliation: Department of Ophthalmology, Shiley Eye Center, University of California, San Diego 92093-0946, USA.
authors.forename: L
authors.initials: L
authors.lastname: Cheng
authors.forename: N A
authors.initials: NA
authors.lastname: Rao
authors.forename: K S
authors.initials: KS
authors.lastname: Keefe
authors.forename: C P
authors.initials: CP
authors.lastname: Avila
authors.forename: J C
authors.initials: JC
authors.lastname: Macdonald
authors.forename: W R
authors.initials: WR
authors.lastname: Freeman
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000188:drug therapy / Q000821:virology; D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis; D000956:Antigens, Viral / Q000276:immunology; D000998:Antiviral Agents / Q000627:therapeutic use; D000077404:Cidofovir; D003587:Cytomegalovirus / Q000276:immunology / Q000302:isolation & purification; D003586:Cytomegalovirus Infections / Q000188:drug therapy / Q000473:pathology / Q000821:virology*; D017726:Cytomegalovirus Retinitis / Q000188:drug therapy / Q000821:virology; D003596:Cytosine / Q000031:analogs & derivatives / Q000627:therapeutic use; D017809:Fatal Outcome; D006801:Humans; D007150:Immunohistochemistry; D007498:Iris / Q000473:pathology / Q000821:virology*; D007500:Iritis / Q000188:drug therapy / Q000473:pathology / Q000821:virology*; D008297:Male; D063065:Organophosphonates; D009943:Organophosphorus Compounds / Q000627:therapeutic use
chemical_list: D000914:Antibodies, Viral; D000956:Antigens, Viral; D000998:Antiviral Agents; D063065:Organophosphonates; D009943:Organophosphorus Compounds; D003596:Cytosine; D000077404:Cidofovir