title: Philadelphia positive acute lymphoblastic leukemia 16 years after the apparent cure of acute lymphoblastic leukemia. New leukemia or late relapse?
abstract: A Philadelphia-positive ALL in an adult occurring 21 years after the initial diagnosis is reported here. This case raises the question as to whether or not this event is a relapse or a new leukemia. A possible role of interferon-alpha previously administered to the patient for a chronic viral hepatitis is discussed too.
authors.forename: J L
authors.initials: JL
authors.lastname: Navarro
authors.forename: J
authors.initials: J
authors.lastname: de Blas Orlando
authors.forename: E
authors.initials: E
authors.lastname: Ríos Herranz
authors.forename: J
authors.initials: J
authors.lastname: González Campos
authors.forename: R
authors.initials: R
authors.lastname: Parody
authors.forename: J M
authors.initials: JM
authors.lastname: Rodríguez Fernández
mesh_terms: D000328:Adult; D000998:Antiviral Agents / Q000009:adverse effects; D002051:Burkitt Lymphoma / Q000175:diagnosis*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006526:Hepatitis C / Q000188:drug therapy; D006521:Hepatitis, Chronic / Q000188:drug therapy; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D016609:Neoplasms, Second Primary / Q000175:diagnosis*; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D012008:Recurrence; D013997:Time Factors
chemical_list: D000998:Antiviral Agents; D016898:Interferon-alpha