title: [Spinal cord injury in multiple myeloma].
abstract: Myelomic spinal cord damage may be a result of both its compression and vascular disorders (squeezing of an artery, disorders of venous outflow). Diagnosis is based on evaluation of the following signs: normochromic anemia; increase of ESR, total protein and calcium levels; discovery of M-gradient in protein fractions of gamma-zone; multiple regions of destruction in spondylogramme. In doubtful cases magneto-resonance and computer tomography were the most informative. Highly effective was therapy with intensive chemoprogramme including either a range of preparations (alkeran, BGNU, cyclophosphan, adriblastina, prednisolon) or a combination of polychemotherapy with irradiation. The operation was indicated in both insufficiency of conservative therapy and increasing of the symptoms of the damage.
authors.forename: Iu S
authors.initials: IuS
authors.lastname: Martynov
authors.forename: V K
authors.initials: VK
authors.lastname: Orlov
authors.forename: D E
authors.initials: DE
authors.lastname: Iarikov
authors.forename: N E
authors.initials: NE
authors.lastname: Andreeva
authors.forename: E I
authors.initials: EI
authors.lastname: Sonina
authors.forename: E L
authors.initials: EL
authors.lastname: Sokov
authors.forename: E V
authors.initials: EV
authors.lastname: Malkova
authors.forename: N V
authors.initials: NV
authors.lastname: Norzdriukhina
authors.forename: N A
authors.initials: NA
authors.lastname: Shuvakhina
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009101:Multiple Myeloma / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D013117:Spinal Cord Compression / Q000150:complications* / Q000175:diagnosis / Q000628:therapy; D014057:Tomography, X-Ray Computed
vernacular_title: [Porazhenie spinnogo mozga pri mnozhestvennoĭ mielome]