Practical synthesis of 2,6-dideoxy-D-lyxo-hexose ("2-deoxy-D-fucose") from D-galactose.
2,6-Dideoxy-D-lyxo-hexose was prepared efficiently from D-galactose in eight steps (25% overall yield). The synthesis is amenable to multigram scale-up.
Shafer
C M
CM
Department of Chemistry, University of California, Davis 95616, USA.
Molinski
T F
TF
D005643:Fucose / Q000031:analogs & derivatives* / Q000138:chemical synthesis; D005690:Galactose / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism
C035338:2-deoxy-L-fucose; D005643:Fucose; D005690:Galactose