Partitioning of dioxins, dibenzofurans, and coplanar PCBS in blood, milk, adipose tissue, placenta and cord blood from five American women.
Partitioning of dioxins, dibenzofurans and the dioxin-like coplanar PCBs was determined by congener-specific high resolution gc-ms analysis of compounds in 6 tissue samples each from 5 women. Samples were whole blood obtained prior to delivery; maternal adipose tissue, cord blood and placenta obtained during cesarean section delivery; and whole blood and milk taken at the time of first obstetrical follow-up examination, one to two months following delivery. All women lived in upstate New York. Specimens were collected in late 1995 and early 1996. Mean measured levels of total PCDDs, PCDFs and coplanar PCBs were 352 pg/g for adipose tissue, 526 pg/g for predelivery blood, 182 pg/g for placenta, 165 pg/g for cord blood, 352 pg/g for postpartum blood and 220 pg/g for milk. Mean total TEQ levels were 11.6 pg/g TEQ for adipose tissue, 12.1 pg/g TEQ for predelivery blood, 10.5 pg/g TEQ for placenta, 5.8 pg/g TEQ for cord blood, 10.0 pg/g TEQ for postpartum blood and 10.2 pg/g TEQ for milk.
Schecter
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Department of Preventive Medicine, SUNY Health Science Center, Binghamton 13903, USA.
Kassis
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I
Päpke
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O
D000273:Adipose Tissue / Q000737:chemistry; D000328:Adult; D001572:Benzofurans / Q000097:blood / Q000493:pharmacokinetics*; D004147:Dioxins / Q000097:blood / Q000493:pharmacokinetics*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D006801:Humans; D008431:Maternal-Fetal Exchange; D008895:Milk, Human / Q000737:chemistry*; D010920:Placenta / Q000737:chemistry; D011078:Polychlorinated Biphenyls / Q000097:blood / Q000493:pharmacokinetics*; D011247:Pregnancy; D014018:Tissue Distribution
D001572:Benzofurans; D004147:Dioxins; D011078:Polychlorinated Biphenyls