Benign spindle cell tumor of the breast with prominent adipocytic component.
We report a rare case of "benign spindle cell tumor of the breast with prominent adipocytic component" and present a review of the literature on the topic. The close morphologic resemblance with myofibroblastoma and spindle cell lipoma of the breast is emphasized and used as a starting point for diagnostic and histogenetic considerations. Although immunocytochemistry and electron microscopy showed features favoring a diagnosis of spindle cell lipoma, they were not conclusive. The tumor described here contributes to widen the spectrum of the benign spindle cell tumors of the breast variously named "benign spindle cell tumor," myofibroblastoma, spindle cell lipoma, and fibroma. It is important to distinguish this lesion from spindle cell metaplastic carcinoma and aggressive fibromatosis.
Magro
G
G
Servizio di Anatomia Patologica, Istituto di Anatomia Patologica, Catania, Italy.
Bisceglia
M
M
Pasquinelli
G
G
D017667:Adipocytes / Q000473:pathology* / Q000648:ultrastructure; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008067:Lipoma / Q000175:diagnosis / Q000473:pathology* / Q000648:ultrastructure; D008854:Microscopy, Electron; D008875:Middle Aged; D009379:Neoplasms, Muscle Tissue / Q000175:diagnosis / Q000473:pathology / Q000648:ultrastructure