title: Torg osteolysis syndrome.
abstract: We describe a 9-year-old girl who initially presented at age 4 with evidence of arthritis in her hands, feet, and large joints. Although she had a partial response to anti-inflammatory medications and had some laboratory results consistent with inflammatory disease, radiographs showed carpal and tarsal osteolysis associated with interphalangeal joint erosions. There was also widening of the shafts of the metacarpals and metatarsals with thinning of the cortices. Based on both the clinical progression of her illness and the radiologic characteristics, this child most likely has the Torg syndrome.
authors.affiliation: Department of Pediatric Immunology and Rheumatology, The Children's Memorial Medical Center and Northwestern University Medical School, Chicago, Illinois 60614, USA.
authors.forename: D M
authors.initials: DM
authors.lastname: Eisenstein
authors.forename: A K
authors.initials: AK
authors.lastname: Poznanski
authors.forename: L M
authors.initials: LM
authors.lastname: Pachman
mesh_terms: D000974:Antibodies, Antinuclear / Q000276:immunology; D001171:Arthritis, Juvenile / Q000000981:diagnostic imaging / Q000276:immunology; D001172:Arthritis, Rheumatoid; D002648:Child; D005260:Female; D005532:Foot Deformities, Congenital / Q000000981:diagnostic imaging; D006228:Hand Deformities, Congenital / Q000000981:diagnostic imaging; D006801:Humans; D007375:Interleukin-1 / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D010014:Osteolysis / Q000151:congenital* / Q000000981:diagnostic imaging; D011859:Radiography; D013577:Syndrome
chemical_list: D000974:Antibodies, Antinuclear; D007375:Interleukin-1; D015850:Interleukin-6