Solid-phase synthesis of single-chain monellin, a sweet protein.
Single-chain monellin, a sweet protein, was synthesized by stepwise solid-phase synthesis. After deprotection, and purification with HPLC, single-chain monellin was obtained in a yield of 0.3% based on the starting resin.
Ota
M
M
Central Research Laboratories, Ajinomoto Co., Inc., Kawasaki, Japan. flr.oota@te11.ajin.omoto.co.jp
Ariyoshi
Y
Y
D002851:Chromatography, High Pressure Liquid; D010940:Plant Proteins / Q000138:chemical synthesis*; D013549:Sweetening Agents / Q000138:chemical synthesis*
D010940:Plant Proteins; D013549:Sweetening Agents; C002541:monellin protein, Dioscoreophyllum cumminsii