title: Hyperhidrosis treated by botulinum A exotoxin.
abstract: BACKGROUND
  Hyperhidrosis, or excessive sweating, can be emotionally challenging and socially and professionally disruptive, and there have been few effective treatments. Recently, botulinum toxin has been demonstrated to be an effective treatment for hyperhidrosis of the axillae and palms and for gustatory sweating.
  
  
  OBJECTIVE
  This article reviews the current treatments and outcomes achieved with chemodenervation of the eccrine sweat glands.
  
  
  RESULTS
  The antihydrotic response lasted 6-17 months for gustatory sweating, 2-8 months for axillary sweating, and 13 weeks to 12 months for palmar sweating.
  
  
  CONCLUSIONS
  Intracutaneous injections of botulinum toxin offer a simple, safe, and effective alternative to other conservative and surgical options.
authors.affiliation: Department of Rehabilitation Medicine, University of Washington, Seattle, USA.
authors.forename: I R
authors.initials: IR
authors.lastname: Odderson
mesh_terms: D019274:Botulinum Toxins, Type A; D006801:Humans; D006945:Hyperhidrosis / Q000628:therapy*; D009465:Neuromuscular Agents; D013545:Sweat Glands / Q000294:innervation*; D013563:Sympathectomy, Chemical; D016896:Treatment Outcome
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A