Acanthosterol sulfates A-J: ten new antifungal steroidal sulfates from a marine sponge Acanthodendrilla sp.
Ten new steroidal sulfates, acanthosterol sulfates A-J (1-10), have been isolated from a marine sponge, Acanthodendrilla sp., collected in western Japan. Acanthosterol sulfates I and J (9 and 10) showed antifungal activity against the yeast Saccharomyces cerevisiae A364A and its mutants at 0.1 mg/disk.
Tsukamoto
S
S
Laboratory of Aquatic Natural Products Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Matsunaga
S
S
Fusetani
N
N
van Soest
R W
RW
D000818:Animals; D000935:Antifungal Agents / Q000302:isolation & purification / Q000494:pharmacology*; D009682:Magnetic Resonance Spectroscopy; D008826:Microbial Sensitivity Tests; D011161:Porifera / Q000737:chemistry*; D012441:Saccharomyces cerevisiae / Q000187:drug effects; D016339:Spectrometry, Mass, Fast Atom Bombardment; D013256:Steroids / Q000302:isolation & purification / Q000494:pharmacology*; D013463:Sulfuric Acid Esters / Q000302:isolation & purification / Q000494:pharmacology*
D000935:Antifungal Agents; D013256:Steroids; D013463:Sulfuric Acid Esters