title: Value of Lesion Morphology and of Residual Stenosis in Predicting Late Clinical Outcomes and Restenosis Rate Post-PTCA in Single-Vessel Disease.
abstract: The study assessed an impact of stenosis morphology before coronary angioplasty (PTCA) and of residual diameter stenosis after the procedure on major adverse cardiac events and restenosis rate at 1 year after intervention in single-vessel disease. Visual analysis of stenoses, using the ABC lesion score system and on-line quantitative evaluation (ACA, DCI, Philips), was performed in 70 patients undergoing PTCA. Recurrence of angina at rest and/or positive treadmill exercise test (TET) >/=6 weeks after PTCA and/or major cardiac events were considered as evidence of restenosis. At 1 year follow-up 56 patients (80%) were event free, without angina at rest and without positive TET, with residual diameter (RD) after PTCA a mean of 2.00 +/- 0.48 mm. In the restenosis group (n = 14) RD was a mean of 1.58 +/- 0.43 mm (p < 0.01): there were three patients with angina at rest, five with Positive TET, and six with cardiac events. In this group, one-half of the stenoses was in class C of the lesion. Residual diameter stenosis, measured objectively after balloon angioplasty, and evaluation of lesion morphology before PTCA can predict late clinical outcomes after the procedure in single-vessel disease.
authors.affiliation: Clinic of Cardiology, Institute of Cardiology, Lodz, Poland
authors.initials: M
authors.lastname: Lelonek
authors.initials: A
authors.lastname: Machraoui