title: Effect of contrast medium dose and image acquisition timing on ureteral opacification in the normal dog as assessed by computed tomography.
abstract: Computed tomography (CT) excretory urography was performed in five adult female dogs after intravenous injection of a bolus of four different doses of water-soluble iodinated contrast medium (100, 200, 400, and 800 mgI/kg). CT images centered over the urinary bladder were performed before injection and 1, 3, 5, 7, 9, 11, 15, 20, 25, 30, 40, 50, and 60 minutes after injection. Opacification of both ureters was evaluated by measuring maximum CT number of individual ureters at each time. Time opacification curves were generated for each dose. Best opacification of the ureters was obtained with 400 and 800 mgI/kg, with a constant peak at 3 minutes and durable opacification for 1 hour. Insufficient opacification was obtained with lower dose of 100 and 200 mgI/kg.
authors.affiliation: Department of Veterinary Clinical Sciences, College of Veterinary Medicine, The Ohio State University, Columbus 43210-1089, USA.
authors.forename: P Y
authors.initials: PY
authors.lastname: Barthez
authors.forename: D
authors.initials: D
authors.lastname: Begon
authors.forename: F
authors.initials: F
authors.lastname: Delisle
mesh_terms: D000818:Animals; D003287:Contrast Media / Q000008:administration & dosage*; D004285:Dogs / Q000033:anatomy & histology*; D005260:Female; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D007275:Injections, Intravenous; D007482:Iothalamate Meglumine / Q000008:administration & dosage*; D011856:Radiographic Image Enhancement / Q000379:methods; D013997:Time Factors; D014057:Tomography, X-Ray Computed / Q000379:methods / Q000662:veterinary*; D014513:Ureter / Q000033:anatomy & histology / Q000000981:diagnostic imaging*; D001743:Urinary Bladder / Q000000981:diagnostic imaging; D014567:Urography / Q000379:methods / Q000662:veterinary
chemical_list: D003287:Contrast Media; C001694:meglumine ioxithalamate; D007482:Iothalamate Meglumine