title: Prevalence of herpes B virus antibody in nonhuman primates reared at the National University of Japan.
abstract: A serological investigation by means of an enzyme immuno assay test for herpes B virus (cercopithecine herpesvirus 1) was performed on 961 sera of healthy nonhuman primates reared in laboratory animal facilities which belong to the Association of Laboratory Animal Facilities of the National University of Japan. An antibody prevalence of 40% (384/ 961) was demonstrated. The antibody titer was shown to be higher among macaques (60% of cynomolgus monkeys, 53% of rhesus monkeys, and 34% of Japanese monkeys) than among non-macaque species (21%). These data indicate that nonhuman primates reared in animal facilities may present an occupational health problem and a potential zoonotic biohazard as demonstrated in limited cases in the United States.
authors.affiliation: Nagasaki University School of Medicine, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Sato
authors.forename: J
authors.initials: J
authors.lastname: Arikawa
authors.forename: M
authors.initials: M
authors.lastname: Furuya
authors.forename: J
authors.initials: J
authors.lastname: Kitoh
authors.forename: K
authors.initials: K
authors.lastname: Mannen
authors.forename: Y
authors.initials: Y
authors.lastname: Nishimune
authors.forename: K
authors.initials: K
authors.lastname: Ohsawa
authors.forename: T
authors.initials: T
authors.lastname: Serikawa
authors.forename: T
authors.initials: T
authors.lastname: Shibahara
authors.forename: Y
authors.initials: Y
authors.lastname: Watanabe
authors.forename: K
authors.initials: K
authors.lastname: Yagami
authors.forename: H
authors.initials: H
authors.lastname: Yamamoto
authors.forename: Y
authors.initials: Y
authors.lastname: Yoshikawa
mesh_terms: D000818:Animals; D000830:Animals, Laboratory / Q000276:immunology*; D000914:Antibodies, Viral / Q000097:blood*; D002521:Cercopithecus / Q000276:immunology; D006568:Herpesvirus 1, Cercopithecine / Q000276:immunology*; D006922:Hylobates / Q000276:immunology; D007564:Japan; D008251:Macaca / Q000276:immunology; D002679:Pan troglodytes / Q000276:immunology; D010215:Papio / Q000276:immunology; D015995:Prevalence; D011323:Primates / Q000276:immunology*; D016036:Seroepidemiologic Studies; D015047:Zoonoses
chemical_list: D000914:Antibodies, Viral