[The morphological characteristics of cell death in different forms of acute tick-borne encephalitis].
The study was aimed to identify different types of cell death in monkey brain in flavivirus experimental encephalitis. 10 brain areas most vulnerable ("indicator") of the disease in its different forms (symptomless, intermediate and severe) were examined in animals infected intracerebrally with viruses of tick-borne encephalitis. Cells of ectodermal and mesenchymal origin displayed apoptosis that was most pronounced in intermediate form of the severity of the disease. Apoptosis was not characteristic for the symptomless form of tick-borne encephalitis. Two types of apoptosis morphological manifestations in nerve cells were described.
Kamalov
N I
NI
Laboratory of Electron Microscopy and Histochemistry, Military Medical Academy, St. Petersburg.
Novozhilova
A P
AP
Kreĭchman
G S
GS
Sokolova
E D
ED
D000208:Acute Disease; D000818:Animals; D017209:Apoptosis; D001921:Brain / Q000473:pathology; D016923:Cell Death; D004195:Disease Models, Animal; D004675:Encephalitis, Tick-Borne / Q000473:pathology*; D016591:Histocytological Preparation Techniques; D008854:Microscopy, Electron; D009336:Necrosis; D009474:Neurons / Q000648:ultrastructure; D010215:Papio; D013116:Spinal Cord / Q000473:pathology
Morfologicheskie osobennosti kletochnoĭ gibeli pri razlichnykh formakh ostrogo kleshchevogo éntsefalita.