title: Long-term effect of prophylactic endoscopic injection sclerotherapy on liver function.
abstract: OBJECTIVE
  The aim of this study was to investigate the long term effect of prophylactic endoscopic injection sclerotherapy (EIS) on liver function.
  
  
  METHODS
  This study was a retrospective investigation of seventy-eight patients with liver cirrhosis, whose liver function was classified as Child's A before follow-up. Laboratory data were retrospectively examined before and after follow-up, and a comparison was made between the EIS group (n=21) and the non-treated group (n=57).
  
  
  RESULTS
  In the 3 or more years of follow-up, cholinesterase and total cholesterol levels deteriorated in several severe-variceal cases. However, these levels did not deteriorate over the 3 or more years of follow-up in the EIS group.
  
  
  CONCLUSIONS
  Prophylactic endoscopic injection sclerotherapy among patients with early stage LC may prevent the deterioration of liver function.
authors.affiliation: The First Department of Internal Medicine, Mie University School of Medicine, Tsu. atarum@clin medic.mie-u.ac.jp
authors.forename: K
authors.initials: K
authors.lastname: Murata
authors.forename: K
authors.initials: K
authors.lastname: Sugimoto
authors.forename: K
authors.initials: K
authors.lastname: Okuda
authors.forename: A
authors.initials: A
authors.lastname: Shimizu
authors.forename: K
authors.initials: K
authors.lastname: Takase
authors.forename: T
authors.initials: T
authors.lastname: Nakano
authors.forename: Y
authors.initials: Y
authors.lastname: Tameda
mesh_terms: D000368:Aged; D002784:Cholesterol / Q000097:blood; D002802:Cholinesterases / Q000097:blood; D016099:Endoscopy, Gastrointestinal; D004932:Esophageal and Gastric Varices / Q000150:complications / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007267:Injections; D008099:Liver / Q000503:physiopathology*; D008103:Liver Cirrhosis / Q000097:blood / Q000150:complications; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015911:Sclerotherapy; D012709:Serum Albumin / Q000032:analysis
chemical_list: D012709:Serum Albumin; D002784:Cholesterol; D002802:Cholinesterases