title: Syringoma: a review of twenty-nine cases.
abstract: The purpose of our study was to identify the clinical characteristics, epidemiologic data and histologic features in 29 cases of syringoma with a duration of lesions prior to the observation between 1 and 25 years. Only one patient complained of moderate itching. In two cases the lesion was solitary, in another the papules formed a lichenified plaque. In six patients only the eyelids were involved and in two patients a symmetrical localization on the forearms was observed. The other 18 patients showed generalized syringoma, 16 with an eruptive onset, 6 of which were familial. One of our cases showed lesions mimicking urticaria pigmentosa and two patients were affected by Down's syndrome. In two cases, histopathology showed association between syringoma and a melanocytic naevus and in one patient with a solitary lesion a clear cell syringoma was observed.
authors.affiliation: Department of Clinical and Experimental Medicine, University of Bologna, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Patrizi
authors.forename: I
authors.initials: I
authors.lastname: Neri
authors.forename: S
authors.initials: S
authors.lastname: Marzaduri
authors.forename: E
authors.initials: E
authors.lastname: Varotti
authors.forename: B
authors.initials: B
authors.lastname: Passarini
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D003937:Diagnosis, Differential; D004314:Down Syndrome / Q000150:complications; D005142:Eyelid Neoplasms / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D005542:Forearm / Q000473:pathology; D006801:Humans; D017495:Hyperpigmentation / Q000473:pathology; D017512:Lichenoid Eruptions / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary / Q000473:pathology; D009508:Nevus, Pigmented / Q000473:pathology; D011537:Pruritus / Q000473:pathology; D013544:Sweat Gland Neoplasms / Q000235:genetics / Q000473:pathology*; D018252:Syringoma / Q000235:genetics / Q000473:pathology*; D014582:Urticaria Pigmentosa / Q000175:diagnosis