[Striatal mechanisms of corticoliberin effect on the behavior of dogs with dopamine deficiency].
Interaction between dopaminergic and corticoliberinergic integrative systems in the process of situation alimentary conditioning, was studied in dogs with chemotrodes indwelled in the caudate nucleus head. Following the CRF administration, the cortisol and catecholamine levels were determined in the blood of intact dogs and in the dogs with 6-OHDA impairment of the substantia nigra. The findings suggest that an interaction between the CRF and dopaminergic systems occurs in the neostriatum.
Voĭlokova
N L
NL
Institute of Physiology of the Russian Acad. Sci., St. Petersburg, Russia.
Suvorov
N F
NF
Rakitskaia
V V
VV
Shaliapina
V G
VG
D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects / Q000502:physiology*; D003214:Conditioning, Classical / Q000187:drug effects / Q000502:physiology; D003346:Corticotropin-Releasing Hormone / Q000494:pharmacology / Q000502:physiology*; D004285:Dogs; D004298:Dopamine / Q000172:deficiency / Q000502:physiology*; D008297:Male; D008526:Medulla Oblongata / Q000187:drug effects; D017072:Neostriatum / Q000187:drug effects / Q000378:metabolism / Q000502:physiology*; D016627:Oxidopamine / Q000633:toxicity; D011930:Reaction Time / Q000187:drug effects / Q000502:physiology; D012018:Reflex / Q000187:drug effects / Q000502:physiology; D013378:Substantia Nigra / Q000187:drug effects / Q000378:metabolism
D016627:Oxidopamine; D003346:Corticotropin-Releasing Hormone; D004298:Dopamine
Striatnye mekhanizmy deĭstviia kortikoliberina na povedenie sobak pri defitsite dofamina.