title: beta-Thalassaemia major in Kuwait.
abstract: A combined retrospective and prospective study of 129 beta-thalassaemia major patients seen between 1965 and 1995 in Sabah Hospital, Kuwait has been carried out. The age range at diagnosis was 2 to 84 months, median 9 months. In approximately 80 per cent, the patients were outcomes of first- or second-cousin marriages. Nine (7 per cent) of the patients were HBsAg positive, while 42 (33 per cent) were hepatitis C seropositive. Eleven (9 per cent) patients had had bone marrow transplantation (BMT). There was no BMT-related mortality, but there were three graft rejections and two cases of chronic graft-versus-host disease (GVHD).
authors.affiliation: Department of Paediatrics, Sabah Hospital Kuwait, Shuwaikh, Kuwait.
authors.forename: L
authors.initials: L
authors.lastname: al-Fuzae
authors.forename: K C
authors.initials: KC
authors.lastname: Aboolbacker
authors.forename: Q
authors.initials: Q
authors.lastname: al-Saleh
mesh_terms: D016026:Bone Marrow Transplantation; D002648:Child; D002675:Child, Preschool; D003241:Consanguinity; D005260:Female; D006508:Hepatitis Antibodies / Q000097:blood; D006801:Humans; D007223:Infant; D007730:Kuwait / Q000453:epidemiology; D008297:Male; D015995:Prevalence; D011446:Prospective Studies; D012189:Retrospective Studies; D017086:beta-Thalassemia / Q000453:epidemiology*
chemical_list: D006508:Hepatitis Antibodies