title: Daily air pollution levels and acute asthma in southern Sweden.
abstract: This study aimed to investigate the association between daily air pollution levels and the occurrence of acute respiratory signs and symptoms among people with asthma or asthma-like problems. Thirty eight subjects in the southern Swedish city of Landskrona kept a daily diary for 10 weeks. The daily prevalence of symptoms, supplementary bronchodilator use and peak flow deviations were compared with measurements of environmental nitrogen dioxide (NO2), sulphur dioxide, temperature and humidity in the city. The occurrence of severe asthma, both during the day and during the evening, was significantly positively associated with the concurrent 24 h average concentration of NO2, which never exceeded 72 microg x m(-3). A correlation of borderline significance was found between the use of on-demand medication and the NO2 level. However, peak flow deviations were not associated with air pollution or weather conditions, which may be explained by the beneficial effect of bronchodilators used by 28 of the subjects. The results of this study confirm those of some earlier studies and suggest that aggravation of asthma is related to daily variations in air quality, as indicated by relatively low ambient concentrations of nitrogen dioxide. These results also indicate that it may be appropriate to examine severe asthma symptoms separately.
authors.affiliation: Dept of Environmental Health, Umeå University, Sweden.
authors.forename: B
authors.initials: B
authors.lastname: Forsberg
authors.forename: N
authors.initials: N
authors.lastname: Stjernberg
authors.forename: R
authors.initials: R
authors.lastname: Linné
authors.forename: B
authors.initials: B
authors.lastname: Segerstedt
authors.forename: S
authors.initials: S
authors.lastname: Wall
mesh_terms: D000208:Acute Disease; D000393:Air Pollutants / Q000009:adverse effects* / Q000032:analysis; D001249:Asthma / Q000139:chemically induced / Q000175:diagnosis / Q000453:epidemiology*; D004784:Environmental Monitoring; D062665:Epidemiological Monitoring; D005260:Female; D006306:Health Surveys; D006801:Humans; D015994:Incidence; D016014:Linear Models; D008297:Male; D009585:Nitrogen Dioxide / Q000009:adverse effects* / Q000032:analysis; D012129:Respiratory Function Tests; D012307:Risk Factors; D012494:Sampling Studies; D013458:Sulfur Dioxide / Q000009:adverse effects* / Q000032:analysis; D013548:Sweden / Q000453:epidemiology; D014505:Urban Population
chemical_list: D000393:Air Pollutants; D013458:Sulfur Dioxide; D009585:Nitrogen Dioxide