NMR studies of salivary glands: from energy metabolism to morphology.
Nuclear magnetic resonance (NMR) spectroscopy has been used to study various physiological functions of salivary glands. This short review summarizes results on energy metabolism and acid-base balance (31P and 14N NMR), electrolytes transport (23Na, 39K, 35Cl and 87Rb NMR) and water transport (1H NMR). The latest development of 1H nuclear magnetic resonance imaging (MRI) allows the three-dimensional structure of salivary glands to be observed with ca. 60 microm resolution, and it is also possible to observe circulation, flow, and volume changes during secretion. The combination of NMR and MRI may open up new fields in the study of exocrine secretion.
Seo
Y
Y
Dept. Physiology, Kyoto Prefectural University of Medicine, Japan. yseo@phys.kpu-m.ac.jp
Murakami
M
M
D000136:Acid-Base Equilibrium / Q000502:physiology*; D000818:Animals; D004734:Energy Metabolism / Q000502:physiology*; D009682:Magnetic Resonance Spectroscopy; D011877:Radionuclide Imaging; D012469:Salivary Glands / Q000166:cytology / Q000000981:diagnostic imaging* / Q000378:metabolism*