Is monoamine oxidase activity elevated in Prader-Willi syndrome?
The platelet contents of monoamine oxidase (MAO-B) were analyzed in 17 children and young adults with Prader-Willi syndrome and 18 non-PWS comparison cases. MAO-B activity was significantly higher in the former group, suggesting monoamine dysfunction in Prader-Willi syndrome.
Akefeldt
A
A
Department of Child and Adolescent Psychiatry, Göteborg University, Annedals Clinics, Sweden.
Månsson
J E
JE
D000293:Adolescent; D000294:Adolescent Behavior / Q000523:psychology; D000328:Adult; D001792:Blood Platelets / Q000201:enzymology*; D015992:Body Mass Index; D016022:Case-Control Studies; D002648:Child; D002652:Child Behavior / Q000523:psychology; D002675:Child, Preschool; D006801:Humans; D007223:Infant; D008995:Monoamine Oxidase / Q000097:blood*; D011218:Prader-Willi Syndrome / Q000201:enzymology* / Q000378:metabolism / Q000523:psychology; D012701:Serotonin / Q000378:metabolism
D012701:Serotonin; D008995:Monoamine Oxidase