Long-term effect of prophylactic endoscopic injection sclerotherapy on liver function.
OBJECTIVE
The aim of this study was to investigate the long term effect of prophylactic endoscopic injection sclerotherapy (EIS) on liver function.


METHODS
This study was a retrospective investigation of seventy-eight patients with liver cirrhosis, whose liver function was classified as Child's A before follow-up. Laboratory data were retrospectively examined before and after follow-up, and a comparison was made between the EIS group (n=21) and the non-treated group (n=57).


RESULTS
In the 3 or more years of follow-up, cholinesterase and total cholesterol levels deteriorated in several severe-variceal cases. However, these levels did not deteriorate over the 3 or more years of follow-up in the EIS group.


CONCLUSIONS
Prophylactic endoscopic injection sclerotherapy among patients with early stage LC may prevent the deterioration of liver function.
Murata
K
K
The First Department of Internal Medicine, Mie University School of Medicine, Tsu. atarum@clin medic.mie-u.ac.jp
Sugimoto
K
K
Okuda
K
K
Shimizu
A
A
Takase
K
K
Nakano
T
T
Tameda
Y
Y
D000368:Aged; D002784:Cholesterol / Q000097:blood; D002802:Cholinesterases / Q000097:blood; D016099:Endoscopy, Gastrointestinal; D004932:Esophageal and Gastric Varices / Q000150:complications / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D007267:Injections; D008099:Liver / Q000503:physiopathology*; D008103:Liver Cirrhosis / Q000097:blood / Q000150:complications; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015911:Sclerotherapy; D012709:Serum Albumin / Q000032:analysis
D012709:Serum Albumin; D002784:Cholesterol; D002802:Cholinesterases