title: Ischemic choroidopathy in primary Sjögren's syndrome.
abstract: OBJECTIVE
  The authors describe a 68-year-old woman in whom ischemic choroidopathy and optic neuropathy developed in association with primary Sjögren's syndrome with central nervous system involvement.
  
  
  METHODS
  Diagnosis of primary Sjögren's syndrome was made upon the association of keratoconjunctivitis sicca, minor salivary gland biopsy and serologic abnormalities. Fluorescein angiography showed signs highly suggestive of ischemic choroidopathy. The authors discuss differential diagnosis and pathophysiology of such choroidal manifestations. Treatment consisted in massive steroid therapy. Secondarily, an immunosuppressant agent (azathioprine) was successfully added because of neurological recurrences.
  
  
  CONCLUSIONS
  Primary Sjögren's syndrome should be considered in the differential diagnosis of ischemic choroidopathy.
authors.affiliation: Department of Ophthalmology, Centre hospitalier universitaire de Fort de France.
authors.forename: P
authors.initials: P
authors.lastname: Rapoport
authors.forename: H
authors.initials: H
authors.lastname: Merle
authors.forename: D
authors.initials: D
authors.lastname: Smadja
mesh_terms: D000368:Aged; D002829:Choroid / Q000098:blood supply*; D003937:Diagnosis, Differential; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007511:Ischemia / Q000150:complications* / Q000175:diagnosis; D009422:Nervous System Diseases / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy; D018917:Optic Neuropathy, Ischemic / Q000150:complications / Q000175:diagnosis; D012008:Recurrence; D012470:Salivary Glands, Minor / Q000473:pathology; D012859:Sjogren's Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D007166:Immunosuppressive Agents