Staphylococcal strains involved in bovine mastitis are inhibited by Staphylococcus aureus antimicrobial peptides.
The inhibitory activity of five bacteriocin (Bac)-producer strains of Staphylococcus aureus was tested against bacteria pathogenic for cattle. Sixty-five epidemiologically unrelated strains of Staph. aureus involved in bovine mastitis were used as indicators in an agar diffusion test. Bacteriocins produced by four strains could inhibit only a limited number of test organisms. However, all 65 indicator strains proved to be susceptible to the combined action of both bacteriocins encoded by pRJ9, a Bac plasmid found in strain A53. Therefore, the bacteriocins produced by this strain may represent new antimicrobial peptides with potential applications in the prevention and treatment of bovine mastitis.
de Oliveira
S S
SS
Departamento de Microbiologia Geral, Universidade Federal do Rio de Janeiro, Brazil.
Abrantes
J
J
Cardoso
M
M
Sordelli
D
D
Bastos
M C
MC
D000818:Animals; D000898:Antibiosis / Q000502:physiology*; D001430:Bacteriocins / Q000378:metabolism*; D002417:Cattle; D005260:Female; D008413:Mastitis / Q000382:microbiology*; D008892:Milk / Q000382:microbiology; D013211:Staphylococcus aureus / Q000378:metabolism / Q000502:physiology*
D001430:Bacteriocins