title: Metastatic hepatocellular carcinoma presenting as hemocholecyst with perforation: a case report.
abstract: In case of hepatocellular carcinoma (HCC), the gallbladder is less frequently involved and metastasis to the gallbladder, together with its significant clinical manifestations, is rarely discussed in the literature in detail. HCC with metastasis to the gallbladder, initially presenting as gallbladder intraluminal hemorrhage and perforation, has not been previously reported. We present a case of HCC disclosed by emergency cholecystectomy for hemocholecyst with perforation. Evaluation of the possible metastatic mechanisms is also discussed.
authors.affiliation: Department of Pathology, Mackay Memorial Hospital, Taipei, Taiwan, ROC.
authors.forename: K M
authors.initials: KM
authors.lastname: Chang
authors.forename: K S
authors.initials: KS
authors.lastname: Jeng
authors.forename: F S
authors.initials: FS
authors.lastname: Yang
authors.forename: B F
authors.initials: BF
authors.lastname: Chen
mesh_terms: D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D005705:Gallbladder Diseases / Q000209:etiology*; D005706:Gallbladder Neoplasms / Q000150:complications / Q000556:secondary*; D006470:Hemorrhage / Q000209:etiology*; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male