Effectiveness of resins in neutralizing antibiotic activities in bactec plus Aerobic/F culture medium.
Incorporating resins in blood culture media can effectively reduce the activities of several antibiotics. It was shown that the activities of some generally used antibiotics decreased by 80 to 90% within 2 h in Bactec Plus Aerobic/F resin-containing culture medium. Bactec vials containing resins were still found to be positive for bacteria when antibiotics were present. The addition of beta-lactamase shortened the detection time irrespective of the presence of resins.
Spaargaren
J
J
Department of Medical Microbiology, Leiden University Medical Centre, 2300 RC, Leiden, The Netherlands.
van Boven
C P
CP
Voorn
G P
GP
D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D016470:Bacteremia / Q000382:microbiology*; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification*; D003470:Culture Media; D006801:Humans; D012116:Resins, Plant / Q000494:pharmacology*
D000900:Anti-Bacterial Agents; D003470:Culture Media; D012116:Resins, Plant