title: Tumor stage in the proximal colon under conditions of a proximal shift of colorectal cancer with age.
abstract: OBJECTIVE
  Although the incidence of proximal colon cancer is known to increase with age, the prognosis of proximal colon cancer remains unclear.
  
  
  METHODS
  One thousand two hundred and five patients with colorectal cancer were analyzed with regard to tumor location, age and Duke's stage.
  
  
  RESULTS
  When Duke's stage was compared with tumor location, an advanced Duke's stage was found more frequently in the proximal colon than in the distal colorectum (p<0.01). In Duke's A colorectal cancer, the incidence of tumors limited to within the submucosal layer decreased from 73.1% in patients under 65 years of age to 60.9% in patients over 65 years of age.
  
  
  CONCLUSIONS
  Since advanced stage cancer was more frequently found in the proximal colon than in the distal colorectum, careful examination for the early detection of proximal colon cancer, particularly in the elderly, is called for.
authors.affiliation: Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Ikeda
authors.forename: N
authors.initials: N
authors.lastname: Koyanagi
authors.forename: M
authors.initials: M
authors.lastname: Mori
authors.forename: S
authors.initials: S
authors.lastname: Minagawa
authors.forename: T
authors.initials: T
authors.lastname: Toyomasu
authors.forename: T
authors.initials: T
authors.lastname: Ezaki
authors.forename: H
authors.initials: H
authors.lastname: Tateishi
authors.forename: K
authors.initials: K
authors.lastname: Sugimachi
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D003106:Colon / Q000473:pathology*; D015179:Colorectal Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged