title: Caries prevention in the 21st century.
abstract: While the incidence of caries has decreased during the past 50 years because of the introduction of water fluoridation and fluoride toothpastes, it is still widespread. Improved therapies, using topical treatments to replace lost calcium and phosphate minerals from early carious lesions, will reduce the need for surgical intervention in the future. Early caries detection techniques currently being developed will allow dentists to maximize the usefulness of these treatments.
authors.affiliation: Technology and Clinical Research, Enamelon Inc., Brunswick, N.J. 08816, USA.
authors.forename: A E
authors.initials: AE
authors.lastname: Winston
authors.forename: S N
authors.initials: SN
authors.lastname: Bhaskar
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002118:Calcium / Q000008:administration & dosage / Q000627:therapeutic use; D002327:Cariostatic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D003731:Dental Caries / Q000175:diagnosis / Q000517:prevention & control*; D005457:Fluoridation; D005459:Fluorides / Q000008:administration & dosage / Q000627:therapeutic use; D005544:Forecasting; D006801:Humans; D015994:Incidence; D008875:Middle Aged; D010710:Phosphates / Q000008:administration & dosage / Q000627:therapeutic use; D018570:Risk Assessment; D012463:Saliva / Q000502:physiology; D014089:Tooth Remineralization / Q000379:methods; D014100:Toothpastes / Q000627:therapeutic use
chemical_list: D002327:Cariostatic Agents; D010710:Phosphates; D014100:Toothpastes; D005459:Fluorides; D002118:Calcium