Pyrrolizidine alkaloids from amphorogyne spicata
Four pyrrolizidine alkaloids, amphorogynines A-D (1-4), which belong to a new type having substituents at C-1 and C-6, were isolated from Amphorogyne spicata (Santalaceae). Their structures were elucidated by spectroscopic methods. The absolute stereochemistry (7aR) of the two main alkaloids, amphorogynines A and D, was determined using chemical correlations.
Thu Huong DT
Institut de Chimie des Substances Naturelles, CNRS, 911978 Gif-sur-Yvette Cedex, France.
Martin
MT
Litaudon
M
Sevenet
T
Pais
M