Cervical cancer: developments in screening and evaluation of the abnormal Pap smear.
Of the more than 50 million Pap smears performed annually in the United States, about 5% of them are abnormal. Although the need for treatment of high-grade lesions is clear, the appropriate management of low-grade lesions remains controversial. New methods of screening for cervical cancer have become available, including testing for the human papilloma virus and improved methods of administering and evaluating the Pap smear. This review addresses new developments in cervical cancer screening and management strategies for when an abnormality is detected.
Walsh
J M
JM
UCSF/Division of General Internal Medicine 94115, USA. jmwalsh@itsa.ucsf.edu
D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D006801:Humans; D008403:Mass Screening / Q000379:methods; D065006:Papanicolaou Test; D027383:Papillomaviridae / Q000302:isolation & purification; D030361:Papillomavirus Infections / Q000175:diagnosis; D014412:Tumor Virus Infections / Q000175:diagnosis; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000628:therapy; D014626:Vaginal Smears / Q000145:classification / Q000379:methods; D002578:Uterine Cervical Dysplasia / Q000175:diagnosis