title: [A successful case report on intralesional OK-432 therapy for cystic mediastinal lymphangiomas].
abstract: A 42-years-old female was referred to the university hospital because of cystic lesions of the right superior mediastinum. Drainage tube was found at right supraclavicular fossa with prolonged lymphatic discharge. We diagnosed this case as a benign cystic lymphangiomas with CT scan and CT scan with cystography and chemical analysis of the contents of the cyst. Intralesional OK-432 therapy for cystic mediastinal lymphangioma was performed. OK-432 was administered through intralesionally placed drainage tube. Excellent result was obtained. A few weeks later, residual lymphatic discharge through drainage tube became stopped. No expansion of the mediastinal cyst was found after drainage tube removal. Intralesional OK-432 therapy for cystic mediastinal lymphangioma was very effective and useful, it should be recommended for the management of the first choice of therapeutic method for cystic mediastinal lymphangioma because of no neurological deficit after this treatment.
authors.affiliation: Second Department of Surgery, Hokkaido University School of Medicine, Sapporo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Okubo
authors.forename: T
authors.initials: T
authors.lastname: Shimada
authors.forename: Y
authors.initials: Y
authors.lastname: Narita
authors.forename: T
authors.initials: T
authors.lastname: Okushiba
authors.forename: M
authors.initials: M
authors.lastname: Douke
authors.forename: T
authors.initials: T
authors.lastname: Takahashi
authors.forename: S
authors.initials: S
authors.lastname: Okushiba
authors.forename: T
authors.initials: T
authors.lastname: Motohara
authors.forename: H
authors.initials: H
authors.lastname: Katou
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D015552:Injections, Intralesional; D018191:Lymphangioma, Cystic / Q000188:drug therapy*; D008479:Mediastinal Neoplasms / Q000188:drug therapy*; D010844:Picibanil / Q000008:administration & dosage*
chemical_list: D000970:Antineoplastic Agents; D010844:Picibanil