title: Retrograde Purkinje potential activation during sinus rhythm following catheter ablation of idiopathic left ventricular tachycardia.
abstract: We describe two patients with idiopathic left ventricular tachycardia that were cured by radiofrequency catheter ablation. Tachycardia was inducible by ventricular stimulation and was verapamil sensitive. Two distinct presystolic potentials (P1 and P2) were recorded during tachycardia in the mid-septal or inferoapical area, but only one potential (P2) was recorded during sinus rhythm. After catheter ablation at this site, the P1 potential was noted after the QRS complex during sinus rhythm, while the P2 was still observed before the QRS complex. The P1 potential showed a decremental property during atrial or ventricular pacing. These data suggest that Purkinje tissue with decremental properties was responsible for the tachycardia mechanism, and that the reentry circuit involving this tissue is likely to be of considerable size.
authors.affiliation: Division of Cardiology, Gunma Prefectural Cardiovascular Center, Maebashi, Japan.
authors.forename: H
authors.initials: H
authors.lastname: Tada
authors.forename: A
authors.initials: A
authors.lastname: Nogami
authors.forename: S
authors.initials: S
authors.lastname: Naito
authors.forename: T
authors.initials: T
authors.lastname: Tomita
authors.forename: S
authors.initials: S
authors.lastname: Oshima
authors.forename: K
authors.initials: K
authors.lastname: Taniguchi
authors.forename: K
authors.initials: K
authors.lastname: Aonuma
authors.forename: Y
authors.initials: Y
authors.lastname: Iesaka
mesh_terms: D000889:Anti-Arrhythmia Agents; D002037:Bundle-Branch Block / Q000503:physiopathology; D017115:Catheter Ablation / Q000009:adverse effects*; D002648:Child; D004558:Electric Stimulation; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D011690:Purkinje Fibers / Q000502:physiology*; D012849:Sinoatrial Node / Q000502:physiology*; D017180:Tachycardia, Ventricular / Q000628:therapy*; D016277:Ventricular Function, Left; D014700:Verapamil
chemical_list: D000889:Anti-Arrhythmia Agents; D014700:Verapamil