title: Postradiation morphea.
abstract: We describe a 54-year-old woman who developed right breast morphea after radiotherapy following a lumpectomy for infiltrating lobular carcinoma. Skin biopsy confirmed the histological features of morphea. Treatment was initiated with both topical and intralesional steroid, resulting in marked improvement. Morphea following radiotherapy is an infrequently recognized phenomenon. However, when diagnosed early it may be effectively managed with local steroid treatment.
authors.affiliation: Department of Medicine, Sunnybrook Health Science Centre, Toronto, Ontario, Canada.
authors.forename: M H
authors.initials: MH
authors.lastname: Gollob
authors.forename: J G
authors.initials: JG
authors.lastname: Dekoven
authors.forename: M J
authors.initials: MJ
authors.lastname: Bell
authors.forename: D
authors.initials: D
authors.lastname: Assaad
authors.forename: J
authors.initials: J
authors.lastname: Rao
mesh_terms: D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D018275:Carcinoma, Lobular / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D002990:Clobetasol / Q000031:analogs & derivatives / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D005938:Glucocorticoids; D006801:Humans; D008875:Middle Aged; D011832:Radiation Injuries; D012594:Scleroderma, Localized / Q000209:etiology* / Q000473:pathology
chemical_list: D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D002990:Clobetasol