[Acquired cystic kidney disease in patients on long-term dialysis: a retrospective study of 125 autopsies. Part 2: tumors].
The possible relation of acquired cystic kidney disease to renal cell carcinoma resulted in an interdisciplinary concern about this disease. Kidneys from 125 autopsies of dialysis patients were studied. Twenty-four of the patients had tumors. Beside four renal adenocarcinomas and two urothelial carcinomas, incidental small tumor nodules were described in 15.1%. Men had more nodules than women. Patients with nodules had a higher average cyst count, often with multi-layered epithelium. There was no difference in age or time of dialysis. This suggests a factor which mediates cyst and tumor proliferation, independent from the time of dialysis. With the improvement in imaging techniques, an increasing number of small renal tumors will be found. Further studies are necessary to evaluate the risk of small kidney cell tumors and their association with acquired cystic kidney disease.
Segerer
S
S
Medizinische Poliklinik, LMU, München.
Meister
P
P
D000368:Aged; D001344:Autopsy; D002292:Carcinoma, Renal Cell / Q000209:etiology / Q000473:pathology*; D005260:Female; D006801:Humans; D052177:Kidney Diseases, Cystic / Q000473:pathology* / Q000628:therapy; D007680:Kidney Neoplasms / Q000209:etiology / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis / Q000009:adverse effects; D012189:Retrospective Studies
Die erworbene, zystische Nierenerkrankung bei chronischen Dialysepatienten: eine retrospektive Studie an 125 Autopsien. Teil 2: Tumoren.