title: Recent advances in gene expression using alphavirus vectors.
abstract: Alphavirus vectors use RNA replication in the cell cytoplasm to direct gene expression. New developments of vectors put persistency of expression and infection of specific cells in focus. Furthermore, a new application shows that the system can be used for production of retrovirus vectors carrying genes with introns and control/regulatory regions.
authors.affiliation: Department of Biosciences at Novum, Huddinge, Sweden. henrik.garoff@cbt.ki.se
authors.forename: H
authors.initials: H
authors.lastname: Garoff
authors.forename: K J
authors.initials: KJ
authors.lastname: Li
mesh_terms: D000524:Alphavirus / Q000235:genetics*; D000818:Animals; D001709:Biotechnology; D003588:Cytopathogenic Effect, Viral; D004274:DNA, Recombinant / Q000235:genetics; D015870:Gene Expression; D005822:Genetic Vectors; D006801:Humans; D012313:RNA / Q000235:genetics; D012093:Replicon; D012190:Retroviridae / Q000235:genetics
chemical_list: D004274:DNA, Recombinant; C039919:RNA, recombinant; D012313:RNA