Transmissible venereal tumor: a retrospective study of 29 cases.
Twenty-nine cases of naturally occurring, transmissible venereal tumor were studied retrospectively. The external genitalia was the primary site of tumor involvement in 27 dogs, with the remaining two dogs having primary intranasal involvement. Extragenital tumor involvement was identified in six cases, including five cases with metastatic disease. Fifteen cases were treated effectively with radiation therapy alone. Radiation therapy also was effective in four cases that were resistant to chemotherapy. Four of five cases treated with at least four doses of vincristine as a solitary agent also achieved complete remissions. Transmissible venereal tumor remains a unique canine tumor that often is curable despite the development of extragenital primary lesions or metastasis.
Rogers
K S
KS
Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, Texas A&M University, College Station 77843-4474, USA.
Walker
M A
MA
Dillon
H B
HB
D000818:Animals; D000972:Antineoplastic Agents, Phytogenic / Q000627:therapeutic use; D004283:Dog Diseases / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D004285:Dogs; D005260:Female; D008297:Male; D009362:Neoplasm Metastasis; D012189:Retrospective Studies; D016896:Treatment Outcome; D014685:Venereal Tumors, Veterinary / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy; D014750:Vincristine / Q000627:therapeutic use
D000972:Antineoplastic Agents, Phytogenic; D014750:Vincristine