title: Outcome after operations for pulmonary atresia with intact ventricular septum.
abstract: OBJECTIVE
  Pulmonary atresia with intact ventricular septum is an anatomically heterogeneous anomaly with a variety of surgical strategies possible. We sought to compare the outcome of patients with a single ventricle approach to those with a biventricular repair and to compare outcome of patients with coronary abnormalities to those with normal coronary arteries.
  
  
  METHODS
  A retrospective review of our surgical database revealed 67 patients with pulmonary atresia with intact ventricular septum operated on between 1981 and 1998. Patients were categorized on the basis of initial surgical strategy: strategy A, aortopulmonary shunt alone (n = 31); strategy B, right ventricular recruitment (n = 32); strategy C, heart transplantation (n = 4). Tricuspid valve size (Z-score) and coronary anatomy were determined. Right ventricular-coronary artery dependency was noted in 8 patients.
  
  
  RESULTS
  Overall actuarial survivals at 1, 5, and 8 years were 82%, 76%, and 76%. Mortality was highest in infancy (10 of 16 deaths). Outcome was equivalent for all 3 strategies. There was no difference in tricuspid valve size between survivors and nonsurvivors (mean Z-score -2.0 (2.5) vs -2.0 (1.9), P =.83). There was no difference in survival based on severity of coronary abnormality. Only one third of patients had a successful biventricular repair, and the tricuspid valve was significantly larger in these than in patients who had Fontan operation (mean Z-score -0.53 [1.6], range -3.5 to 1, versus mean Z-score -3.03 [2.7], range -5.5 to 0, P =.002).
  
  
  CONCLUSIONS
  Surgical outcome for patients born with pulmonary atresia with intact ventricular septum is satisfactory. The strategies of biventricular repair, single ventricle palliation, and heart transplantation allow for equal outcome among all anatomic subtypes.
authors.affiliation: Divisions of Cardiology and Cardiothoracic Surgery, Children's Hospital of Philadelphia, PA 19104, USA.
authors.forename: J
authors.initials: J
authors.lastname: Rychik
authors.forename: H
authors.initials: H
authors.lastname: Levy
authors.forename: J W
authors.initials: JW
authors.lastname: Gaynor
authors.forename: W M
authors.initials: WM
authors.lastname: DeCampli
authors.forename: T L
authors.initials: TL
authors.lastname: Spray
mesh_terms: D017023:Coronary Angiography; D005500:Follow-Up Studies; D006346:Heart Septum; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D018633:Pulmonary Atresia / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D012189:Retrospective Studies; D015996:Survival Rate; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures