title: [Efficacy and efficiency of antitubercular treatment in health jurisdictions of Morelos].
abstract: OBJECTIVE
  To evaluate the efficacy and efficiency of tuberculosis treatment administered by the Secretaría de Salud (SSA) in the sanitary jurisdictions of Cuernavaca and Cuautla, Morelos, for the 1992-1996 period by retrospectively reviewing tuberculosis treatment control cards.
  
  
  METHODS
  Official Norm for Tuberculosis Prevention and Control in Primary Care Units outcome definitions were used. Data was collected on standardized forms and analyzed with SAS and Epi Info programs; 149 primary care units and 4 hospitals in the study area were visited.
  
  
  RESULTS
  There were found 288 patients cards, of which 260 were new cases. These patients received 311 treatments of which 85% were directly observed. Reviewed cards represented 60% of SSA notified cases for this period. There were analyzed 246 treatments of which 32% were bacteriological cures, 26% probable cures, 18% dropouts, 1% failures and 3% deaths. In 20% of treatments the outcome was unknown. Cure rate was better in new cases (61%) than in retreatments (38%), p < 0.01. Efficacy of treatment was 71% and efficiency 58%. Patients receiving retreatment abandoned it more frequently (32%) than new cases (16%), p < 0.01. A statistically significant association was found between abandoned treatment and being retreated (OR = 3.3, CI 95% 1.3-8.5, p = 0.01) or belonging to a lower socioeconomic level (OR = 2.3, CI 95% 1.0-4.9, p = 0.04). In the 34 retreatment programs, 22 were initiated after abandonment, failure or relapse.
  
  
  CONCLUSIONS
  Proportion of cure rate (58%) compares unfavorably with WHO recommendations (85%). Implications of a high dropout rate and probability of circulation of resistant strains of M tuberculosis are discussed. Creative strategies to reinforce patient compliance which take into account the patient and not only the health services, extension of cultures to known M. tuberculosis drug resistance and evaluation of modifications to drug regimens are proposed. Review of treatment control cards is a useful tool for program evaluation.
authors.affiliation: Instituto Nacional de Salud Pública, México.
authors.forename: M L
authors.initials: ML
authors.lastname: García-García
authors.forename: M E
authors.initials: ME
authors.lastname: Mayar-Maya
authors.forename: L
authors.initials: L
authors.lastname: Ferreyra-Reyes
authors.forename: M
authors.initials: M
authors.lastname: Palacios-Martínez
authors.forename: C
authors.initials: C
authors.lastname: Alvarez-García
authors.forename: J L
authors.initials: JL
authors.lastname: Valdespino-Gómez
mesh_terms: D000328:Adult; D018563:Disease Notification / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D008800:Mexico / Q000453:epidemiology; D010349:Patient Compliance; D012189:Retrospective Studies; D012959:Socioeconomic Factors; D016896:Treatment Outcome; D014376:Tuberculosis / Q000188:drug therapy* / Q000453:epidemiology
vernacular_title: Eficacia y eficiencia del tratamiento antituberculoso en jurisdicciones sanitarias de Morelos.