title: Microbial glycoconjugates.
abstract: The surfaces of all microbes are 'sugar coated' with molecules such as lipopolysaccharides in Gram-negative bacteria, capsular polysaccharides in bacteria, lipoarabinomannans in mycobacteria and lipophosphoglycan in Leishmania. The basic structures of these glycoconjugates are known and, in the case of pathogens, they can function as virulence determinants. Recent publications have refined some of these structures and have elucidated interesting genes and proteins responsible for their biosynthesis.
authors.affiliation: Department of Biochemistry, University of Kentucky Medical Center, Lexington 40536-0084, USA.
authors.forename: B J
authors.initials: BJ
authors.lastname: Mengeling
authors.forename: S J
authors.initials: SJ
authors.lastname: Turco
mesh_terms: D000818:Animals; D056890:Eukaryota / Q000378:metabolism* / Q000472:pathogenicity; D014453:Glucuronosyltransferase / Q000235:genetics; D006028:Glycosphingolipids / Q000096:biosynthesis; D017261:Glycosylphosphatidylinositols / Q000378:metabolism*; D016695:Glycosyltransferases; D000076002:Hyaluronan Synthases; D007891:Leishmania / Q000378:metabolism; D008070:Lipopolysaccharides / Q000737:chemistry* / Q000378:metabolism*; D008565:Membrane Proteins; D009161:Mycobacterium / Q000378:metabolism; D017862:Phycodnaviridae / Q000201:enzymology* / Q000235:genetics; D014166:Transferases; D029867:Xenopus Proteins
chemical_list: D006028:Glycosphingolipids; D017261:Glycosylphosphatidylinositols; D008070:Lipopolysaccharides; D008565:Membrane Proteins; D029867:Xenopus Proteins; C050016:lipoarabinomannan; C008290:lipophosphonoglycan; D014166:Transferases; D016695:Glycosyltransferases; D014453:Glucuronosyltransferase; C056944:HAS1 protein, Xenopus; D000076002:Hyaluronan Synthases