title: [Endoscopic diagnosis of early cancer in the esophagogastric junctional region].
abstract: The endoscopic diagnosis of early esophageal and gastric cancers located within 2 cm above and below the esophagogastric junction (EGJ) is discussed. We reviewed 25 cases (10 mucosal cancers and 15 submucosal cancers). Histologically, early cancers frequently appeared as type IIc lesions (16/25: 64%). There was no relationship between tumor size and the depth of invasion of cancer lesions, and most of the lesions were well or moderately differentiated carcinomas. Endoscopically, homogenous redness with a thin white coating, some granular appearance, and easy bleeding were very important factors for the diagnosis of early gastric cancer. For superficial esophageal cancer, differential diagnosis from reflux esophagitis is correctly performed with the endoscopic dye (lugol)-staining method and biopsy. In order not to overlook early cancer at the EGJ, this area should be observed with sufficient air inflation by the U-turn or J-turn method using a frontal-view panendoscope.
authors.affiliation: Department of Endoscopic Diagnosis and Therapy, Tokyo Medical and Dental University School of Medicine, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Takeshita
authors.forename: T
authors.initials: T
authors.lastname: Kawano
authors.forename: N
authors.initials: N
authors.lastname: Saito
authors.forename: K
authors.initials: K
authors.lastname: Nagai
authors.forename: M
authors.initials: M
authors.lastname: Tani
authors.forename: T
authors.initials: T
authors.lastname: Honda
authors.forename: H
authors.initials: H
authors.lastname: Inoue
authors.forename: K
authors.initials: K
authors.lastname: Yano
authors.forename: S
authors.initials: S
authors.lastname: Hayashi
authors.forename: I
authors.initials: I
authors.lastname: Saeki
authors.forename: T
authors.initials: T
authors.lastname: Iwai
mesh_terms: D000328:Adult; D000368:Aged; D003937:Diagnosis, Differential; D016099:Endoscopy, Gastrointestinal; D004938:Esophageal Neoplasms / Q000473:pathology*; D004942:Esophagitis, Peptic / Q000473:pathology; D004943:Esophagogastric Junction; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D013274:Stomach Neoplasms / Q000473:pathology*