Anaphylaxis to paracetamol.
We hereby present a patient suffering several episodes of anaphylaxis (generalized urticaria, dyspnea, wheezing and intense cough) a few minutes after taking different drugs containing paracetamol. Intradermal test with pure paracetamol (100 mg/ml) was positive. It was negative in six controls. Serum specific IgE anti-paracetamol (by RIA) was negative. Anaphylaxis from paracetamol is rare but has been reported. Positive skin test with paracetamol have only been rarely described.
Galindo
P A
PA
Allergy Section, Ciudad Real Hospital Complex, Spain.
Borja
J
J
Mur
P
P
Feo
F
F
Gómez
E
E
García
R
R
D000082:Acetaminophen / Q000009:adverse effects*; D000328:Adult; D000707:Anaphylaxis / Q000097:blood / Q000139:chemically induced* / Q000175:diagnosis; D004342:Drug Hypersensitivity / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D007428:Intradermal Tests
D000082:Acetaminophen; D007073:Immunoglobulin E