[Geotyping of wild poliovirus strains on the territory of Russia and CIS countries in 1987-1995].
33 wild poliovirus strains isolated on the territory of the former USSR were subjected to the comparative sequence analysis of the 150 bp genome fragment VP1/2A on the junction of the genome regions coding basic capsid protein VP1 and viral protease 2A. The dendrograms characterizing the similarity of nucleotide sequences revealed the existence of 3 geographical genotypes (geotypes) of wild poliovirus strains of type 1 (A, G, T) and broad geotype (C) of wild poliovirus strains of type 3. The comparison of the analyzed strains with strains circulating in the neighboring countries at the same period provided information on their genetic relationship. The data thus obtained made it possible to establish the pathways of the transmission of wild poliovirus strains in the common epidemic area of the Russia u CIS.
Lipskaia
G Iu
GIu
Institute of Physico-Chemical Biology, Lomonosov State University, Chumakov Institute of Poliomyelitis and Viral Encephalitis, Moscow, Russia.
Cherkasova
E A
EA
Ivanova
O E
OE
Drozdov
S G
SG
D017517:Commonwealth of Independent States; D016679:Genome, Viral; D017955:Poliovirus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D012426:Russia; D017422:Sequence Analysis, DNA; D012703:Serotyping
Geotipirovanie dikikh shtammov virusa poliomielita, izolirovannykh na territorii Rossii i SNG v 1987-1995 gg.