title: [Study of gastric emptying by dual isotopes. Corrections due to contamination].
abstract: The evaluation of gastric emptying by the double isotope technique involves some methodologic conditioning. Among them contamination correction or interference in the energy windows of the activity of the two isotopes used in the marking of the solids and fluids of the test food are important. The results of an experiment in which a phantom was used to evaluate the contamination between indio 111 (DTPA-Ca111In) and technecium 99m (colloid99mTc). Three test studies were posteriorly performed in healthy volunteers and 27 studies in a control group (13 males, mean age of 33 years, mean body mass index 39.02 kg/m). In these studies the contamination was corrected with the acquisition, following an initial swallow of juice marked with 111In, of activity in the windows of both isotopes. The contamination of 111In (isotope of greatest radiation energy) in the window of 99mTc was 24% in the phantom and 20%, 23% and 26% in the three initial study tests. The mean contamination in the control group was of 22% with limits of 19% to 29% and a standard deviation of 3%. Despite the comparable results, the usefulness of the individualized contamination calculation in the studies of gastric emptying with dual isotope to minimize the methodologic errors of this technique is discussed.
authors.affiliation: Servicio de Medicina Digestiva, Hospital La Fe, Valencia.
authors.forename: P
authors.initials: P
authors.lastname: Nos
authors.forename: V
authors.initials: V
authors.lastname: Garrigues
authors.forename: E
authors.initials: E
authors.lastname: Caballero
authors.forename: M C
authors.initials: MC
authors.lastname: Cano
authors.forename: R
authors.initials: R
authors.lastname: Sopena
authors.forename: J
authors.initials: J
authors.lastname: Ponce
mesh_terms: D000328:Adult; D005502:Food; D005746:Gastric Emptying / Q000502:physiology*; D006801:Humans; D007205:Indium Radioisotopes; D007553:Isotope Labeling / Q000592:standards*; D008297:Male; D013667:Technetium
chemical_list: D007205:Indium Radioisotopes; D013667:Technetium
vernacular_title: Estudio del vaciamiento gástrico mediante técnica con doble isótopo. Consideraciones con respecto a la corrección de la contaminación.