An outbreak of Bacillus species in a cancer hospital.
Bacillus species were recovered from the blood cultures of 39 oncology patients over 14 weeks. A matched case-control study showed a strong association of Bacillus species bacteremia with use of calcium gluconate solution (odds ratio=25.0) and of central venous lines (odds ratio=8.8). Stopping use of the implicated calcium gluconate vials controlled the outbreak.
Thuler
L C
LC
Hospital Infection Control Committee, Hospital of Cancer, National Cancer Institute, Rio de Janeiro, Brazil.
Velasco
E
E
de Souza Martins
C A
CA
de Faria
L M
LM
da Fonseca
N P
NP
Dias
L M
LM
Gonçalves
V M
VM
D000293:Adolescent; D000328:Adult; D000368:Aged; D016863:Bacillaceae Infections / Q000453:epidemiology* / Q000209:etiology; D001938:Brazil / Q000453:epidemiology; D002125:Calcium Gluconate; D002173:Cancer Care Facilities / Q000706:statistics & numerical data*; D016022:Case-Control Studies; D002405:Catheterization, Central Venous / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000453:epidemiology* / Q000209:etiology; D004196:Disease Outbreaks; D004340:Drug Contamination; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D016555:Matched-Pair Analysis; D008875:Middle Aged; D016017:Odds Ratio; D012996:Solutions
D012996:Solutions; D002125:Calcium Gluconate