title: [Computer-assisted analysis of mammograms in routine clinical diagnosis].
abstract: OBJECTIVE
  Computer-aided diagnosis in mammography is a topic many study groups have been concerned with since the first presentation of a system for computer-aided interpretation in 1967. Currently, there is only one system available for clinical use in mammaography, the CAD-System Image Checker (R2 Technology). The purpose of our prospective study was to evaluate whether the integration of the CAD-system into the routine of a radiological breast diagnosis unit is feasible.
  
  
  RESULTS
  After the installation of the CAD-system, 300 patients with 1110 mammograms were included for evaluation in the present study. In 54 of these cases histological examination was indicated due to suspect criteria on conventional mammography. In 39 of 54 cases (72.2%) malignancy could be proven histologically. The CAD-system marked 82.1% of the histologically verified carcinomas correctly. 94.3% of all 1797 marks made by the CAD-system indicated normal or benign structures. Routinely performed CAD analysis prolonged patients waiting time by about 15 min because the marks of the CAD system had to be interpreted in addition to the routine diagnostic investigations.
  
  
  CONCLUSIONS
  Our experience with the use of the CAD-system in daily routine showed that CAD analysis can easily be integrated into a preexisting mammography unit. However, the diagnostic benefit is not yet clearly established. Since the rate of false negative marks by the CAD-system Image Checker is still high, the results of CAD analysis must be checked and corrected by an observer well experienced in mammography reading.
authors.affiliation: Institut für Radiologische Diagnostik, Klinikum Grosshadern, Ludwig-Maximilians-Universität München.
authors.forename: H
authors.initials: H
authors.lastname: Sittek
authors.forename: C
authors.initials: C
authors.lastname: Perlet
authors.forename: R
authors.initials: R
authors.lastname: Helmberger
authors.forename: E
authors.initials: E
authors.lastname: Linsmeier
authors.forename: M
authors.initials: M
authors.lastname: Kessler
authors.forename: M
authors.initials: M
authors.lastname: Reiser
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D003936:Diagnosis, Computer-Assisted; D005260:Female; D006801:Humans; D008327:Mammography / Q000379:methods*
vernacular_title: Computerassistierte Analyse von Mammographien in der klinischen Routinediagnostik.