Sorption of non-narcotic analgetic drugs of medicinal charcoal.
Adsorption of four 5-pyrazolone derivatives and two carboxylic acids from aqueous solutions was studied. Partition coefficients for the analyzed drugs were calculated. Good corelation between log(k1, k2) (Langmuir constants) and log (octanol-water partition coefficient) of the drugs were found. The higher log(k1k2) value the higher solubility of the non-narcotic and analgetic drugs.
Sobczak
H
H
Department of Inorganic and Analytical Chemistry, Karol Marcinkowski University of Medical Sciences, Poznań, Poland.
Pawlaczyk
J
J
D000327:Adsorption; D000701:Analgesics, Opioid / Q000737:chemistry*; D002606:Charcoal; D055598:Chemical Phenomena; D002627:Chemistry, Physical; D007202:Indicators and Reagents; D013816:Thermodynamics
D000701:Analgesics, Opioid; D007202:Indicators and Reagents; D002606:Charcoal