Recent advances in site-directed spin labeling of proteins.
Site-directed spin labeling of proteins is experiencing a phase of rapid technical evolution, application and evaluation. New strategies have been introduced for determining membrane protein topography, electrostatic potentials, the orientation of proteins at membrane surfaces and inter-residue distances. New applications include studies of beta strands, structure mapping using spin-spin interactions, domain motions in soluble proteins and extensive structural analysis of a number of membrane and soluble proteins.
Hubbell
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Jules Stein Eye Institute, University of California, Los Angeles 90095, USA. hubbellw@jsei.ucla.edu
Gross
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Langen
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Lietzow
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D002462:Cell Membrane / Q000737:chemistry; D011487:Protein Conformation; D017433:Protein Structure, Secondary; D011506:Proteins / Q000737:chemistry*; D013113:Spin Labels; D055672:Static Electricity
D011506:Proteins; D013113:Spin Labels