title: Atomic force microscopy and other scanning probe microscopies.
abstract: The highlight of the past year is the unfolding and refolding of the muscle protein titin in the atomic force microscope. A related highlight in the intersection between experiment and theory is a recent review of the effects of molecular forces on biochemical kinetics. Other advances in scanning probe microscopy include entropic brushes, molecular sandwiches and applications of atomic force microscopy to gene therapy.
authors.affiliation: Department of Physics, University of California, Santa Barbara 93106, USA.
authors.forename: H G
authors.initials: HG
authors.lastname: Hansma
authors.forename: L
authors.initials: L
authors.lastname: Pietrasanta
mesh_terms: D017304:Annexin A5 / Q000737:chemistry; D001426:Bacterial Proteins / Q000737:chemistry; D010582:Bacteriophage lambda / Q000737:chemistry; D064211:Connectin; D004268:DNA-Binding Proteins; D012321:DNA-Directed RNA Polymerases / Q000737:chemistry; D007797:Laminin / Q000737:chemistry*; D016239:MEDLINE / Q000706:statistics & numerical data; D008564:Membrane Potentials; D008565:Membrane Proteins / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D009124:Muscle Proteins / Q000737:chemistry*; D009218:Myosins / Q000737:chemistry*; D017510:Protein Folding; D011494:Protein Kinases / Q000737:chemistry*; D051877:RNA Polymerase Sigma 54; D012808:Sigma Factor / Q000737:chemistry; D014481:United States
chemical_list: D017304:Annexin A5; D001426:Bacterial Proteins; D064211:Connectin; D004268:DNA-Binding Proteins; D007797:Laminin; D008565:Membrane Proteins; D009124:Muscle Proteins; D012808:Sigma Factor; D011494:Protein Kinases; D012321:DNA-Directed RNA Polymerases; D051877:RNA Polymerase Sigma 54; D009218:Myosins