title: Two cases of idiopathic CD4+ T-lymphocytopenia in elderly patients.
abstract: We present 2 cases of idiopathic CD4+ T-lymphocytopenia (ICL) in elderly patients. Case 1, a 73-year-old man, with pneumonia had received several antibiotics with unsuccessful results at another hospital. On admission, his CD4+ T-lymphocyte count was 109/microl and Pneumocystis carinii was detected by bronchoalveolar lavage fluid staining. No evidence of human immunodeficiency virus (HIV) infection was found. Despite therapy, the patient died of respiratory failure. Case 2, a 72-year-old man, contracted severe pneumonia, and Hemophillus influenzae was believed to be the pathogen. On admission, his CD4+ T-lymphocyte count was 238/microl. No evidence of HIV infection was found. He received antibiotics and improved successfully. We suggest that ICL may currently be incubating in a number of elderly pneumonia patients.
authors.affiliation: Department of Respiratory Medicine, National Minami-kyushu Hospital, Kagoshima.
authors.forename: W
authors.initials: W
authors.lastname: Matsuyama
authors.forename: T
authors.initials: T
authors.lastname: Tsurukawa
authors.forename: F
authors.initials: F
authors.lastname: Iwami
authors.forename: J
authors.initials: J
authors.lastname: Wakimoto
authors.forename: A
authors.initials: A
authors.lastname: Mizoguchi
authors.forename: M
authors.initials: M
authors.lastname: Kawabata
authors.forename: M
authors.initials: M
authors.lastname: Osame
mesh_terms: D000368:Aged; D018791:CD4 Lymphocyte Count; D017809:Fatal Outcome; D006192:Haemophilus Infections / Q000150:complications; D006801:Humans; D008231:Lymphopenia / Q000097:blood / Q000150:complications / Q000188:drug therapy; D008297:Male; D009894:Opportunistic Infections / Q000150:complications; D018410:Pneumonia, Bacterial / Q000097:blood / Q000150:complications; D011020:Pneumonia, Pneumocystis / Q000097:blood / Q000150:complications*; D012008:Recurrence; D012131:Respiratory Insufficiency / Q000209:etiology