Antibiotic resistance pattern of enterotoxigenic Escherichia coli isolated from infants and young adults in Israel.
The aim of this study was to describe antibiotic resistance rates of enterotoxigenic Escherichia coli in Israel in order to facilitate the empirical choice of antibiotic treatment or prophylaxis for traveler's diarrhea and infantile diarrhea in our region. A total of 281 enterotoxigenic Escherichia coli isolates were tested: 144 from Bedouin infants and 137 from Israeli soldiers. Antibiotic-resistant isolates were prevalent in both groups, but higher resistance rates were found in the pediatric group. Strains producing heat-labile toxin showed higher resistance rates than strains producing heat-stable toxin. The results obtained in Israel preclude the use of many commonly used antibiotics for the treatment of traveler's diarrhea. Quinolones, however, are still effective.
Turner
D
D
Pediatric Infectious Disease Unit, Soroka Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Porat
N
N
Cohen
D
D
Yavzori
M
M
Fraser
D
D
Peled
N
N
Ohana
O
O
Dagan
R
R
D000293:Adolescent; D000328:Adult; D001427:Bacterial Toxins / Q000096:biosynthesis*; D003967:Diarrhea / Q000382:microbiology*; D003968:Diarrhea, Infantile / Q000382:microbiology; D004352:Drug Resistance, Microbial; D004768:Enterotoxins / Q000096:biosynthesis*; D004926:Escherichia coli / Q000187:drug effects* / Q000302:isolation & purification / Q000378:metabolism; D004927:Escherichia coli Infections / Q000382:microbiology*; D029968:Escherichia coli Proteins; D005006:Ethnicity; D006801:Humans; D007223:Infant; D007557:Israel; D008889:Military Personnel; D014195:Travel; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology
D001427:Bacterial Toxins; D004768:Enterotoxins; D029968:Escherichia coli Proteins; C034151:heat stable toxin (E coli); D015662:Trimethoprim, Sulfamethoxazole Drug Combination; C027538:heat-labile enterotoxin, E coli