title: Expression of the GPDH-4 isozyme of sn-glycerol-3-phosphate dehydrogenase in three Drosophila species.
abstract: A fourth recently discovered isozyme of sn-glycerol-3-phosphate dehydrogenase (GPDH-4) in Drosophila melanogaster is shown to be a translational product of the Gpdh transcript which contains exons 1 through 7. This transcript was also found in two other Drosophila species, D. busckii and D. virilis. In contrast to D. melanogaster and D. busckii, the Gpdh transcript containing exons 1-6 is absent in D. virilis adults. The reason for this difference between D. virilis and the two other species is intriguing but remains elusive. We have ruled out the possibility that a replacement of an amino acid residue in exon 7 played any role in generating this interspecific variation.
authors.affiliation: Molecular Genetics and Evolution Group, Research School of Biological Sciences, Australian National University, Canberra, ACT, Australia. tomasz@rsbs.anu.edu.au
authors.forename: T M
authors.initials: TM
authors.lastname: Wilanowski
authors.forename: S H
authors.initials: SH
authors.lastname: Yoong
authors.forename: S
authors.initials: S
authors.lastname: Bartoszewski
authors.forename: J B
authors.initials: JB
authors.lastname: Gibson
mesh_terms: D000818:Animals; D004251:DNA Transposable Elements; D004330:Drosophila / Q000201:enzymology* / Q000235:genetics* / Q000254:growth & development; D004331:Drosophila melanogaster / Q000201:enzymology / Q000235:genetics; D005091:Exons; D018507:Gene Expression Regulation, Developmental; D050536:Glycerol-3-Phosphate Dehydrogenase (NAD+); D005993:Glycerolphosphate Dehydrogenase / Q000235:genetics* / Q000378:metabolism; D007527:Isoenzymes; D007814:Larva / Q000201:enzymology; D014170:Transformation, Genetic
chemical_list: D004251:DNA Transposable Elements; D007527:Isoenzymes; D005993:Glycerolphosphate Dehydrogenase; D050536:Glycerol-3-Phosphate Dehydrogenase (NAD+)