[Expression of the tumor suppressor gene p53 in superficial transitional carcinoma of the bladder].
Presentation of 113 cases of transitional cells surface tumours of the bladder where p53 protein expression has been used and compared to known prognostic factors. The existence of a statistically significant relationship between this expression and the tumoral grade and stage in all studied groups has been noticed. It can be concluded that the expression of this protein can be useful as a new prognostic factor, even though it is still necessary to conduct more studies, basically prospective.
Menéndez López
V
V
Servicio de Urología, Hospital General Universitario de Elche, Universidad Miguel Hernández.
Molina Porto
R
R
Alcaráz Asensio
A
A
Alvarez-Vijande García
R
R
Alcover García
J A
JA
Ballesta Gimeno
M A
MA
Carretero González
P
P
D000368:Aged; D000369:Aged, 80 and over; D002295:Carcinoma, Transitional Cell / Q000235:genetics*; D005260:Female; D015972:Gene Expression Regulation, Neoplastic / Q000235:genetics*; D016158:Genes, p53 / Q000235:genetics*; D006801:Humans; D008297:Male; D008875:Middle Aged; D001749:Urinary Bladder Neoplasms / Q000235:genetics*
Expresión del gen supresor tumoral p53 en los carcinomas transicionales superficiales de vejiga.