Radioimmunoassisted surgery for lung metastases from colorectal cancer: results and perspectives.
The high incidence of resectable lung metastases from colorectal cancer and the very poor prognosis of untreated patients (less than 24-month survival) has promoted the surgical approach to treatment. Since the main aims of this kind of surgery are the complete resection of the tumor, the preservation of tumor-free parenchyma, and a minimal surgical trauma, innovative surgical techniques have been developed. We report on our experience in the radioimmunoassisted pulmonary metastasectomy by the use of a hand-held gamma-detecting probe (GDP) and describe the application of the intraoperative radioimmunolocalization of tumor to video-assisted minimally invasive surgery.
Prati
U
U
Department of Surgery, University of Pavia IRCCS Policlinico San Matteo, Italy.
Roveda
L
L
Scoppetta
N
N
Ngntejeu
S T
ST
Trotta
F
F
Valsecchi
P
P
Zonta
A
A
D000911:Antibodies, Monoclonal; D002272:Carcinoembryonic Antigen / Q000276:immunology; D015179:Colorectal Neoplasms / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D007432:Intraoperative Period; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary* / Q000601:surgery*; D019060:Minimally Invasive Surgical Procedures; D016719:Radioimmunodetection; D016019:Survival Analysis
D000911:Antibodies, Monoclonal; D002272:Carcinoembryonic Antigen