Typing of human Mycobacterium avium isolates in Italy by IS1245-based restriction fragment length polymorphism analysis.
All but 2 of 63 Mycobacterium avium isolates from distinct geographic areas of Italy exhibited markedly polymorphic, multibanded IS1245 restriction fragment length polymorphism (RFLP) patterns; 2 isolates showed the low-number banding pattern typical of bird isolates. By computer analysis, 41 distinct IS1245 patterns and 10 clusters of essentially identical strains were detected; 40% of the 63 isolates showed genetic relatedness, suggesting the existence of a predominant AIDS-associated IS1245 RFLP pattern.
Lari
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Dipartimento di Patologia Sperimentale, Biotecnologie Mediche, Infettivologia ed Epidemiologia, Università di Pisa, I-56127 Pisa, Italy.
Cavallini
M
M
Rindi
L
L
Iona
E
E
Fattorini
L
L
Garzelli
C
C
D000163:Acquired Immunodeficiency Syndrome / Q000382:microbiology; D015373:Bacterial Typing Techniques; D004251:DNA Transposable Elements; D006801:Humans; D009162:Mycobacterium avium / Q000145:classification*; D012150:Polymorphism, Restriction Fragment Length
D004251:DNA Transposable Elements