[Effect of solution pH on the reactivity of the isolated segment of the rat mesenteric artery subjected stretching of various degree].
Experiments on the rat mesenteric artery's segments at different degrees of its stretching showed no influence of acidosis or alkalosis on the vessel wall tension within a wide range of pH (7.8-6.6). Acidification of the solution (7.0 or 6.6) inhibited the vessel response to noradrenaline or electrical field stimulation (EFS). On the contrary, the acidification potentiated a constriction caused by the EFS at a high level of vascular tone.
Iartsev
V N
VN
Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg, Russia.
Karachentseva
O V
OV
Dvoretskiĭ
D P
DP
D000818:Animals; D004558:Electric Stimulation; D004791:Enzyme Inhibitors / Q000494:pharmacology; D006863:Hydrogen-Ion Concentration; D066298:In Vitro Techniques; D008297:Male; D017538:Mesenteric Artery, Superior / Q000187:drug effects* / Q000502:physiology; D009119:Muscle Contraction / Q000187:drug effects; D009126:Muscle Relaxation / Q000187:drug effects; D009131:Muscle, Smooth, Vascular / Q000187:drug effects / Q000502:physiology; D009569:Nitric Oxide / Q000037:antagonists & inhibitors; D019335:Nitroarginine / Q000494:pharmacology; D009638:Norepinephrine / Q000494:pharmacology; D051381:Rats; D017208:Rats, Wistar; D012996:Solutions; D013314:Stress, Mechanical; D014662:Vasoconstrictor Agents / Q000494:pharmacology
D004791:Enzyme Inhibitors; D012996:Solutions; D014662:Vasoconstrictor Agents; D019335:Nitroarginine; D009569:Nitric Oxide; D009638:Norepinephrine
Vliianie pH rastvora na reaktivnost' isolirovannogo segmenta bryzheechnoĭ arterii krysy pri razlichnoĭ stepeni ego rastiazheniia.