title: Primary surgical cure of stage III-B cervical carcinoma with adnexal metastasis.
abstract: Management of patients with advanced stage cervical carcinoma remains suboptimal. Primary radiation therapy has been the standard treatment for years. Despite some changes in radiation technique, cure rates for advanced stage cervical cancer remain disappointing. Radiation complications in those patients can also be severe. We report here a case of a patient who presented with renal failure from bilateral ureteral obstruction from stage III-B cervical squamous carcinoma. The patient underwent a primary total pelvic exenteration with low rectosigmoid reanastomosis, urinary conduit construction, and cecal neovagina construction as definitive treatment. She was found to have metastasis to the broad ligament, ovary, and fallopian tube. Surgical margins and lymph nodes were negative. The patient did not receive any radiation therapy or chemotherapy. The patient is alive, healthy, and without evidence of disease 8 years following treatment.
authors.affiliation: Gynecologic Oncology Associates, Hoag Hospital Cancer Center, 351 Hospital Road, Suite 507, Newport Beach, California, 92663, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Micha
authors.forename: J V
authors.initials: JV
authors.lastname: Brown
mesh_terms: D000291:Adnexal Diseases / Q000601:surgery*; D005260:Female; D005833:Genital Neoplasms, Female / Q000556:secondary*; D006801:Humans; D007044:Hysterectomy; D008875:Middle Aged; D009367:Neoplasm Staging; D010385:Pelvic Exenteration; D002583:Uterine Cervical Neoplasms / Q000473:pathology / Q000601:surgery*