title: Comparison of two-dimensional MR digital subtraction angiography of the lower extremity with x-ray angiography.
abstract: OBJECTIVE
  To perform a preliminary evaluation of the diagnostic accuracy of contrast-enhanced, two-dimensional (2D) magnetic resonance (MR) digital subtraction angiography (DSA) of the lower extremity by comparison with x-ray angiography (XRA).
  
  
  METHODS
  Forty lower extremities in 22 patients were imaged at multiple levels with both XRA and 2D MR DSA. Images were retrospectively analyzed by three radiologists in a randomized blinded manner. Seventeen vascular segments were graded as an insignificant lesion, a significant lesion, or as an occlusion. With the use of segments well depicted with XRA as the gold standard, the sensitivity, specificity, and accuracy of 2D MR DSA, as compared with XRA, were evaluated. The McNemar-Stuart-Maxwell test was performed to determine the significance of any differences found.
  
  
  RESULTS
  Three hundred eighty-three arterial segments were evaluated with both techniques. Three hundred one segments were well depicted with XRA. There was no significant difference between 2D MR DSA and XRA for assessing the degree of occlusive disease in these 301 segments (.25 < P < .5). The sensitivity, specificity, and diagnostic accuracy of 2D MR DSA were found to be 90%, 98%, and 93%, respectively.
  
  
  CONCLUSIONS
  Two-dimensional MR DSA is an accurate method for assessing arterial lesions in the lower extremity.
authors.affiliation: Department of Radiology, Cornell University Medical College, New York, NY 10021, USA.
authors.forename: P A
authors.initials: PA
authors.lastname: Winchester
authors.forename: H M
authors.initials: HM
authors.lastname: Lee
authors.forename: N M
authors.initials: NM
authors.lastname: Khilnani
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.forename: D W
authors.initials: DW
authors.lastname: Trost
authors.forename: H L
authors.initials: HL
authors.lastname: Bush
authors.forename: T A
authors.initials: TA
authors.lastname: Sos
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015901:Angiography, Digital Subtraction; D001157:Arterial Occlusive Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D003287:Contrast Media; D005240:Feasibility Studies; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000473:pathology; D005360:Fibula / Q000098:blood supply; D005528:Foot / Q000098:blood supply; D006801:Humans; D007083:Iliac Artery / Q000000981:diagnostic imaging / Q000473:pathology; D007866:Leg / Q000098:blood supply* / Q000000981:diagnostic imaging; D018810:Magnetic Resonance Angiography; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery / Q000000981:diagnostic imaging / Q000473:pathology; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D016037:Single-Blind Method; D013382:Subtraction Technique; D016909:Tibial Arteries / Q000000981:diagnostic imaging / Q000473:pathology
chemical_list: D003287:Contrast Media