title: Paraganglioma of the vagina: the first report of a rare tumor in a child.
abstract: Paraganglioma (extra-adrenal pheochromocytoma) is a rare tumor, particularly in childhood. Those in the female genital tract are exceptionally rare, with only 9 cases reported in detail since 1926. All were seen in adults and only two arose in the vagina. This study examined the incidence of this tumor in the childhood population of the West Midlands region of the United Kingdom since 1957 and found 4 cases: 2 abdominal, 1 para-aortic, and 1 carotid body. A recent additional case is reported in the vagina of a child aged 11 years, who presented with heavy vaginal bleeding in the absence of hypertension. Initial diagnosis suggested rhabdomyosarcoma and near complete excision was carried out. Since this is the first such case to be described in a child, the outcome can only be assumed. Although histopathological examination suggested the benign nature of the tumor, implying that surgical excision was sufficient treatment, close follow-up is recommended.
authors.affiliation: West Midlands Regional Children's Tumour Research Group, Birmingham Children's Hospital NHS Trust, UK.
authors.forename: S E
authors.initials: SE
authors.lastname: Parkes
authors.forename: F
authors.initials: F
authors.lastname: Raafat
authors.forename: B J
authors.initials: BJ
authors.lastname: Morland
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D010235:Paraganglioma / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D012208:Rhabdomyosarcoma / Q000175:diagnosis; D014625:Vaginal Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology / Q000601:surgery