title: The clinical spectrum of post-streptococcal syndromes with arthritis in children.
abstract: Acute rheumatic fever (ARF) and post-streptococcal reactive arthritis (PSRA) are well known complications of streptococcal throat infections. We describe four children with arthritis following a streptococcal throat infection. In addition to arthritis, other clinical manifestations included erythema nodosum, livedo reticularis and cutaneous vasculitis. Because of the very diverse clinical manifestations that may appear after a streptococcal throat infection, we suggest a classification and treatment of post-streptococcal syndromes according to the severity of the disease.
authors.affiliation: Department of Pediatrics, Rijnstate Hospital, Arnhem, The Netherlands.
authors.forename: L
authors.initials: L
authors.lastname: Bont
authors.forename: F
authors.initials: F
authors.lastname: Brus
authors.forename: R H
authors.initials: RH
authors.lastname: Dijkman-Neerincx
authors.forename: T L
authors.initials: TL
authors.lastname: Jansen
authors.forename: J W
authors.initials: JW
authors.lastname: Meyer
authors.forename: M
authors.initials: M
authors.lastname: Janssen
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D016918:Arthritis, Reactive / Q000382:microbiology* / Q000473:pathology; D002648:Child; D002675:Child, Preschool; D004893:Erythema Nodosum / Q000150:complications / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D009336:Necrosis; D012213:Rheumatic Fever / Q000382:microbiology* / Q000473:pathology; D012867:Skin / Q000098:blood supply; D017445:Skin Diseases, Vascular / Q000150:complications / Q000473:pathology; D013290:Streptococcal Infections / Q000150:complications / Q000382:microbiology*; D013297:Streptococcus pyogenes / Q000302:isolation & purification; D013577:Syndrome; D014657:Vasculitis / Q000150:complications / Q000473:pathology