title: [The characteristics of the development of postvaccinal diphtheria immunity in children under elevated technogenic environmental pollution in the region near the Dnieper River].
abstract: Condition was studied of collective specific immunity against diphtheria in vaccinated children who ranged from 2 to 15 years old, living in the industrial region of Pridneprovye, with special reference for the degree of the technogenous environmental pollution. To determine specific cellular sensibilization to diphtherial antigen. LAIT was used for the first time. The studies made showed that in a region under health-hazard conditions lower level of antitoxic antidiphtherial immunity occurs more frequently than in non-polluted areas (twice as much of the values), which fact suggests that technologeous pollution may have a suppressive effect on formation of postvaccinal immunity. Apart from measuring the level of specific antibodies for control of the formation of the immune responsiveness to be monitored you may use LAIT and measure levels of R-proteins.
authors.forename: L R
authors.initials: LR
authors.lastname: Shostakovich-Koretskaia
authors.forename: O M
authors.initials: OM
authors.lastname: Iakunina
authors.forename: V V
authors.initials: VV
authors.lastname: Mavrutenkov
mesh_terms: D000293:Adolescent; D000907:Antibodies, Bacterial / Q000097:blood; D000917:Antibody Formation; D002648:Child; D002675:Child, Preschool; D003353:Corynebacterium diphtheriae / Q000276:immunology; D004165:Diphtheria / Q000517:prevention & control*; D004168:Diphtheria Toxoid / Q000276:immunology*; D004787:Environmental Pollution / Q000009:adverse effects*; D006801:Humans; D007111:Immunity, Cellular; D007223:Infant; D011897:Random Allocation; D014455:Ukraine; D014505:Urban Population
chemical_list: D000907:Antibodies, Bacterial; D004168:Diphtheria Toxoid
vernacular_title: Osobennosti formirovaniia postvaktsinal'nogo protivodifteriĭnogo immuniteta u deteĭ v usloviiakh povyshennogo tekhnogennogo zagriazneniia okruzhaiushcheĭ sredy Pridneprovskogo regiona.