title: [Functional characteristics of foot skin mechanoreceptors and afferent nerve fibers of the sciatic nerve after central axotomy of sensory neurons].
abstract: The activity of mechanoreceptors was studied in normal rats' hindfoot and compared with that of rhizotomised animals. Evoked nerve impulses were recorded from afferent fibres of the n.tibialis. A possible autonomous functioning of decentralised mechanoreceptors, even though in an altered fashion, was shown. The registered shifts comprised a decrease in sensitivity to mechanical stimulation and lower adaptive properties. The findings suggest that the underlying mechanism involves a probable lack of trophic interaction leading to interruption of a link between the CNS and the peripheral nervous system.
authors.affiliation: Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg, Russia.
authors.forename: L I
authors.initials: LI
authors.lastname: Kolosova
authors.forename: G N
authors.initials: GN
authors.lastname: Akoev
authors.forename: A B
authors.initials: AB
authors.lastname: Moiseeva
authors.forename: O V
authors.initials: OV
authors.lastname: Riabchikova
mesh_terms: D000344:Afferent Pathways / Q000502:physiology*; D000818:Animals; D019771:Axotomy; D004594:Electrophysiology; D005727:Ganglia, Spinal / Q000502:physiology*; D006614:Hindlimb / Q000502:physiology; D008297:Male; D008465:Mechanoreceptors / Q000502:physiology*; D009412:Nerve Fibers / Q000502:physiology*; D009475:Neurons, Afferent / Q000502:physiology* / Q000648:ultrastructure; D010812:Physical Stimulation; D051381:Rats; D017208:Rats, Wistar; D012584:Sciatic Nerve / Q000502:physiology* / Q000648:ultrastructure; D012879:Skin Physiological Phenomena
vernacular_title: Issledovanie funktsional'nykh kharakteristik retseptorov kozhi stopy i afferentnykh nervnykh volokon sedalishchnogo nerva krysy posle tsentral'noĭ aksotomii sensornykh neĭronov.