title: Multi-anode detection in electrospray ionization time-of-flight mass spectrometry.
abstract: An electrospray ionization ion source coupled to a time-of-flight mass analyzer incorporating a multi-anode time-to-digital converter is described. High-speed data acquisition (kHz mass spectral acquisition) rates are achieved. The four-anode detector produces a significant increase in detection/counting efficiency over that for a single-anode detector. In this work a 2.5 times increase in detection efficiency is demonstrated. The multi-anode detector is also used as a diagnostic tool to optimize transmission of the ion optics.
authors.affiliation: Department of Chemistry, Texas A&M University, College Station 77843, USA.
authors.forename: D C
authors.initials: DC
authors.lastname: Barbacci
authors.forename: D H
authors.initials: DH
authors.lastname: Russell
authors.forename: J A
authors.initials: JA
authors.lastname: Schultz
authors.forename: J
authors.initials: J
authors.lastname: Holocek
authors.forename: S
authors.initials: S
authors.lastname: Ulrich
authors.forename: W
authors.initials: W
authors.lastname: Burton
authors.forename: M
authors.initials: M
authors.lastname: Van Stipdonk
mesh_terms: D003574:Cytochrome c Group / Q000737:chemistry; D003626:Data Display; D003627:Data Interpretation, Statistical; D004566:Electrodes; D006801:Humans; D013058:Mass Spectrometry / Q000295:instrumentation / Q000379:methods*
chemical_list: D003574:Cytochrome c Group