title: Trypanosoma cruzi: compromise of reproductive system in acute murine infection.
abstract: Infection of isolated organs of the reproductive system by Trypanosoma cruzi has been described since Chagas' disease was first studied. A detailed histopathological analysis of mice acutely infected with T. cruzi CL strain showed colonization of male (preputial glands and skin, penis, testicular albuginea, epididymis, vas deferens, seminal vesicles, prostate, coagulative, bulbo urethral and urethral glands) and female (vagina, uterus, oviduct, ovary, mesovary, clitoris and mammary glands) structures of the reproductive system. The results presented herein demonstrated invasion of epithelial cells, pronounced colonization of the epididymis and male genital adnexa, but absence of parasitism in penile corpora cavernosa.
authors.affiliation: Department of Pathology, Instituto Oswaldo Cruz, FIOCRUZ, Rio de Janeiro, Brazil. hlenzi@gene.dbbm.fiocruz.br
authors.forename: H L
authors.initials: HL
authors.lastname: Lenzi
authors.forename: M T
authors.initials: MT
authors.lastname: Castelo-Branco
authors.forename: M
authors.initials: M
authors.lastname: Pelajo-Machado
authors.forename: D N
authors.initials: DN
authors.lastname: Oliveira
authors.forename: C R
authors.initials: CR
authors.lastname: Gattass
mesh_terms: D000818:Animals; D014355:Chagas Disease / Q000469:parasitology*; D005260:Female; D005836:Genitalia, Female / Q000469:parasitology* / Q000648:ultrastructure; D005837:Genitalia, Male / Q000469:parasitology* / Q000648:ultrastructure; D008297:Male; D008321:Mammary Glands, Animal / Q000469:parasitology; D051379:Mice; D008807:Mice, Inbred BALB C; D018613:Microscopy, Confocal; D014349:Trypanosoma cruzi / Q000302:isolation & purification*