Solitary rectal ulcer syndrome accompanied by submucosal invasive carcinoma.
We report a case of carcinoma in solitary rectal ulcer syndrome. The diagnosis was made by colonoscopic appearance and biopsy. A tumor measuring 0.9 x 0.6 cm was found in a resected solitary rectal ulcer. The lesion exhibited typical histological features of solitary rectal ulcer syndrome, with a well differentiated adenocarcinoma invading submucosal layers and some dysplastic glands. We believe that the adenocarcinoma represents a malignant transformation from solitary rectal ulcer syndrome, because similar to longstanding chronic idiopathic colitis, colorectal dysplasia and carcinoma may develop.
Tsuchida
K
K
First Department of Internal Medicine, Nagoya City University Medical School, Nagoya, Japan.
Okayama
N
N
Miyata
M
M
Joh
T
T
Yokoyama
Y
Y
Itoh
M
M
Kobayashi
K
K
Nakamura
T
T
D000230:Adenocarcinoma / Q000473:pathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012002:Rectal Diseases / Q000473:pathology*; D012004:Rectal Neoplasms / Q000473:pathology*; D014456:Ulcer / Q000473:pathology*