Lipid A-induced oxidative stress requires protein tyrosine kinases and protein kinase C activation, but not intracellular calcium mobilization in human polymorphonuclear leukocytes.
Benquet
C
C
Maisonneuve-Rosemont Hospital, Research Center, Montreal, Canada.
Kouassi
E
E
D000328:Adult; D002118:Calcium / Q000378:metabolism*; D002614:Chelating Agents / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D006801:Humans; D066298:In Vitro Techniques; D008050:Lipid A / Q000009:adverse effects*; D009504:Neutrophils / Q000378:metabolism*; D018384:Oxidative Stress / Q000502:physiology; D011493:Protein Kinase C / Q000037:antagonists & inhibitors / Q000378:metabolism*; D011505:Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism*; D019311:Staurosporine / Q000494:pharmacology; D013997:Time Factors
D002614:Chelating Agents; D008050:Lipid A; D017382:Reactive Oxygen Species; D011505:Protein-Tyrosine Kinases; D011493:Protein Kinase C; D019311:Staurosporine; D002118:Calcium