title: [Splenic infarct in heterozygote sickle cell trait (Hb AS)].
abstract: We present a carrier of the sickle cell trait who developed a serious splenic infarction. An antecedent hypoxaemic event and a blood coagulation disorder were ruled out. The observation shows that the sickle cell trait can represent a risk factor for a life-threatening thrombotic event, even in the absence of a predisposing condition.
authors.affiliation: Kantonsspital Olten.
authors.forename: R
authors.initials: R
authors.lastname: von Känel
authors.forename: M
authors.initials: M
authors.lastname: Pirovino
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D006580:Genetic Carrier Screening; D006451:Hemoglobin, Sickle / Q000235:genetics*; D006801:Humans; D007238:Infarction / Q000097:blood / Q000175:diagnosis / Q000235:genetics*; D008297:Male; D012307:Risk Factors; D012805:Sickle Cell Trait / Q000097:blood / Q000175:diagnosis / Q000235:genetics*; D013154:Spleen / Q000098:blood supply*
chemical_list: D006451:Hemoglobin, Sickle
vernacular_title: Milzinfarkt bei heterozygoter Sichelzellanlage (Hb AS).