Q-T interval prolongation and pleomorphic ventricular tachyarrhythmia ('Torsade de pointes') in organophosphate poisoning: report of a case.
1. A 63-year-old woman presented with drowsy consciousness and dyspnea, followed by respiratory failure, after taking a bottle of parathion for suicide. 2. Sinus tachycardia was noted initially by ECG and Q-T interval prolongation with pleomorphic ventricular tachyarrhythmia ('Torsade de pointes') occurred on the third day of admission. 3. Torsade de pointes was relieved by magnesium sulfate and atropine sulfate intravenously. Q-T interval returned to normal on the fifth day of admission. 4. Practicing physicians should be aware of this uncommon type of cardiac toxicity caused by organophosphate poisoning, Q-T interval prolongation and pleomorphic ventricular tachyarrhythmia.
Wang
M H
MH
Department of Internal Medicine, National Taiwan University Hospital, Taipei, ROC.
Tseng
C D
CD
Bair
S Y
SY
D001285:Atropine / Q000627:therapeutic use; D004562:Electrocardiography / Q000187:drug effects; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007306:Insecticides / Q000506:poisoning*; D008133:Long QT Syndrome / Q000139:chemically induced*; D008278:Magnesium Sulfate / Q000627:therapeutic use; D008875:Middle Aged; D010278:Parathion / Q000506:poisoning*; D013405:Suicide; D016171:Torsades de Pointes / Q000139:chemically induced* / Q000188:drug therapy
D007306:Insecticides; D010278:Parathion; D008278:Magnesium Sulfate; D001285:Atropine