Paraneoplastic encephalomyelitis and seminoma: importance of testicular ultrasonography.
We report two patients with paraneoplastic limbic and brainstem encephalitis associated with occult nonmetastatic testicular seminoma. In each patient, the neoplasm was detectable only by testicular ultrasonography. Male patients with this syndrome in whom lung cancer is not found should undergo testicular ultrasonography as part of the search for an extrapulmonary neoplasm. A normal clinical testicular examination is insufficient to exclude an occult seminoma.
Wingerchuk
D M
DM
Department of Neurology, Mayo Clinic and Foundation, Rochester, MN 55905, USA.
Noseworthy
J H
JH
Kimmel
D W
DW
D000328:Adult; D001921:Brain / Q000473:pathology*; D001933:Brain Stem / Q000473:pathology*; D002114:Calcinosis / Q000000981:diagnostic imaging; D003937:Diagnosis, Differential; D004679:Encephalomyelitis / Q000175:diagnosis* / Q000209:etiology; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009919:Orchiectomy; D010257:Paraneoplastic Syndromes / Q000175:diagnosis* / Q000209:etiology; D018239:Seminoma / Q000000981:diagnostic imaging* / Q000601:surgery; D013116:Spinal Cord / Q000473:pathology; D013736:Testicular Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D013737:Testis / Q000000981:diagnostic imaging* / Q000473:pathology; D014463:Ultrasonography