Phosphorylcholine-coated metallic stents in rabbit iliac and porcine coronary arteries.
The arterial wall reaction to phosphorylcholine-coated metal stents was examined in rabbits and pigs. Compared to non-coated stents, no significant difference was found by angiography and histology. We conclude that although phosphorylcholine-coating does not provoke arterial neointima formation or decrease luminal diameter compared to stainless steel stents, the coating does not seem to reduce restenosis.
Kuiper
K K
KK
Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.
Robinson
K A
KA
Chronos
N A
NA
Cui
J
J
Palmer
S J
SJ
Nordrehaug
J E
JE
D000792:Angiography; D000818:Animals; D001158:Arteries / Q000473:pathology* / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation* / Q000379:methods; D020099:Coated Materials, Biocompatible; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000473:pathology / Q000601:surgery; D046508:Culture Techniques; D004195:Disease Models, Animal; D007083:Iliac Artery / Q000000981:diagnostic imaging / Q000601:surgery; D008297:Male; D008422:Materials Testing; D008670:Metals; D010767:Phosphorylcholine / Q000737:chemistry; D011817:Rabbits; D012016:Reference Values; D015607:Stents; D013552:Swine; D013556:Swine, Miniature
D020099:Coated Materials, Biocompatible; D008670:Metals; D010767:Phosphorylcholine