title: Calculated dosimetric parameters of the IoGold 125I source model 3631-A.
abstract: Basic dosimetric parameters as recommended by the AAPM Task Group No. 43 (TG-43) have been determined for recently available IoGold 125I brachytherapy seeds. Monte Carlo methods (MCNP) were used in the calculation of these parameters in water, and results compared with soon to be published experimental parameters also for 125I IoGold seeds as well with parameters for model 6702 and 6711 125I seeds. These parameters were the radial dose function, anisotropy factor and constant, and the dose rate constant. Using MCNP, values for the radial dose function at 0.5, 2.0, and 5.0 cm were 1.053, 0.877, and 0.443, respectively. The anisotropy factor was 0.975, 0.946, 0.945, and 0.952 at 0.5, 1.0, 2.0, and 5.0 cm, respectively, with an anisotropy constant of 0.95. The IoGold dose rate constant was determined by excluding the low energy titanium characteristic x rays produced in the IoGold titanium capsule. Using this post TG-43 revised NIST air kerma methodology, the IoGold dose rate constant was 0.96 cGy h-1 U-1. These calculatively determined parameters for IoGold seeds were compared with those determined experimentally for IoGold seeds, and also compared with parameters determined for model 6702 and 6711 seeds as presented in TG-43.
authors.affiliation: Department of Radiation Oncology, Wayne State University, Detroit, Michigan 48201, USA. jwierzbi@smmcsag.org
authors.forename: J G
authors.initials: JG
authors.lastname: Wierzbicki
authors.forename: M J
authors.initials: MJ
authors.lastname: Rivard
authors.forename: D S
authors.initials: DS
authors.lastname: Waid
authors.forename: V E
authors.initials: VE
authors.lastname: Arterbery
mesh_terms: D016880:Anisotropy; D001918:Brachytherapy / Q000295:instrumentation* / Q000379:methods / Q000592:standards; D004867:Equipment Design; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use*; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D011786:Quality Control; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D014867:Water
chemical_list: D007457:Iodine Radioisotopes; D014867:Water