Transfusion-related acute lung injury associated with an NA1-specific antigranulocyte antibody.
Transfusion-related acute lung injury (TRALI) is an infrequent complication of hemotherapy. Antigranulocyte antibodies, most of them present in donor's serum, have been implicated in its pathogenesis. We describe a case of TRALI, following red blood cell transfusion, associated with an antigranulocyte antibody with NA1 specificity in the patient's serum.
Santamaría
A
A
Moya
F
F
Martinez
C
C
Martino
R
R
Martinez-Pérez
J
J
Muñiz-Díaz
E
E
D000368:Aged; D000906:Antibodies / Q000276:immunology; D019644:Arthroplasty, Replacement, Hip; D017707:Erythrocyte Transfusion / Q000009:adverse effects*; D005260:Female; D006801:Humans; D007519:Isoantigens / Q000276:immunology*; D008171:Lung Diseases / Q000276:immunology* / Q000473:pathology; D009504:Neutrophils / Q000276:immunology* / Q000473:pathology
D000906:Antibodies; D007519:Isoantigens; C067704:neutrophil-specific antigen NA1, human