Expression of heterologous proteins in stable insect cell culture.
Stable transformed insect cell lines have been used for producing many highly processed heterologous proteins. Current research has focused on development of new expression and selection systems, and enhancement of vector stability. Defining the variation of modification and processing capabilities between cell lines will further enhance complex protein production from insect cells.
Pfeifer
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Department of Zoology, University of British Columbia, Vancouver, Canada. pfeifer@zoology.ubc.ca
D000818:Animals; D001709:Biotechnology; D002461:Cell Line, Transformed; D015870:Gene Expression; D005822:Genetic Vectors; D007313:Insecta; D017924:Nucleopolyhedroviruses / Q000235:genetics; D011499:Protein Processing, Post-Translational; D011994:Recombinant Proteins / Q000235:genetics*
D011994:Recombinant Proteins