title: Botulinum toxin type A for facial rejuvenation. United States and United Kingdom perspectives.
abstract: BACKGROUND
  Botulinum A toxin has been well documented as a successful treatment for hyperfunctional upper facial expression lines. Currently, there are two commercial sources for botulinum toxin--Botox and Dysport. Only Botox is currently available in the United States; however, both Botox and Dysport are available in a number of European and other countries.
  
  
  OBJECTIVE
  There are several differences between these two sources of botulinum toxin, including different potency of their dosage units. This article will review the uses of these two sources of botulinum toxin and discuss the dilution and dosing of botulinum toxin for facial expression lines.
  
  
  RESULTS
  One unit of Botox is approximately equivalent in potency to 4 U of Dysport.
  
  
  CONCLUSIONS
  Both commercial types of botulinum toxin can be used interchangeably with appropriate dosage selection.
authors.affiliation: Department of Dermatology, University of California, Los Angeles, School of Medicine, USA.
authors.forename: N J
authors.initials: NJ
authors.lastname: Lowe
mesh_terms: D019274:Botulinum Toxins, Type A / Q000008:administration & dosage*; D005152:Facial Muscles / Q000187:drug effects* / Q000294:innervation; D006801:Humans; D007273:Injections, Intramuscular / Q000379:methods; D009121:Muscle Denervation; D009465:Neuromuscular Agents / Q000008:administration & dosage*; D012060:Rejuvenation; D015595:Skin Aging / Q000187:drug effects*; D006113:United Kingdom; D014481:United States
chemical_list: D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A