title: Effect of creatine loading on endurance capacity and sprint power in cyclists.
abstract: The effect of creatine loading on endurance capacity and sprint performance was investigated in elite cyclists according to a double-blind cross-over study design. Subjects (n = 12) underwent on 3 occasions and separated by 5 week wash-out periods, a 2 h 30 min standardized endurance protocol on their own race bicycle, which was mounted on an electromagnetically braked roller-system, whereupon they cycled to exhaustion at their predetermined 4 mmol lactate threshold. Immediately thereafter they performed 5 maximal 10 second sprints, separated by 2 min recovery intervals, on a Monark bicycle ergometer at 6 kg resistance on the flywheel. Before the exercise test, subjects were either creatine loaded (C: 25 g creatine monohydrate/day, 5 days) or were creatine loaded plus ingested creatine during the exercise test (CC: 5 g/h), or received placebo (P). Compared with P, C but not CC increased (p<0.05) peak and mean sprint power output by 8-9% for all 5 sprints. Endurance time to exhaustion was not affected by either C or CC. It is concluded that creatine loading improves intermittent sprint capacity at the end of endurance exercise to fatigue. This ergogenic action is counteracted by high dose creatine intake during exercise.
authors.affiliation: Faculty of Physical Education and Physiotherapy, Department of Kinesiology, Katholieke Universiteit Leuven, Belgium.
authors.forename: F
authors.initials: F
authors.lastname: Vandebuerie
authors.forename: B
authors.initials: B
authors.lastname: Vanden Eynde
authors.forename: K
authors.initials: K
authors.lastname: Vandenberghe
authors.forename: P
authors.initials: P
authors.lastname: Hespel
mesh_terms: D000293:Adolescent; D000328:Adult; D001642:Bicycling / Q000502:physiology*; D003401:Creatine / Q000494:pharmacology*; D018592:Cross-Over Studies; D019587:Dietary Supplements; D004311:Double-Blind Method; D005080:Exercise Test; D006801:Humans; D008297:Male; D010807:Physical Endurance / Q000502:physiology*
chemical_list: D003401:Creatine