title: Response to venlafaxine in a previously antidepressant treatment-resistant combat veteran with post-traumatic stress disorder.
abstract: Post-traumatic stress disorder (PTSD) is frequently treated with antidepressant medications, especially the newer selective serotonergic antidepressants which have documented efficacy in PTSD. Analogous to depression, however, some PTSD patients may not have a satisfactory response to these agents. This case report describes a PTSD patient who did not respond to several serotonergic antidepressants, but did improve with venlafaxine which has both noradrenergic and serotonergic properties.
authors.affiliation: Ralph H. Johnson VA Medical Center and the Medical University of South Carolina, Charleston 29401, USA. hamner mark b@charlestonva.gov
authors.forename: M B
authors.initials: MB
authors.lastname: Hamner
authors.forename: B C
authors.initials: BC
authors.lastname: Frueh
mesh_terms: D018687:Antidepressive Agents, Second-Generation / Q000627:therapeutic use*; D003511:Cyclohexanols / Q000627:therapeutic use*; D004351:Drug Resistance; D006801:Humans; D008297:Male; D008875:Middle Aged; D017367:Selective Serotonin Reuptake Inhibitors / Q000627:therapeutic use*; D013313:Stress Disorders, Post-Traumatic / Q000188:drug therapy* / Q000523:psychology; D000069470:Venlafaxine Hydrochloride; D014728:Veterans
chemical_list: D018687:Antidepressive Agents, Second-Generation; D003511:Cyclohexanols; D017367:Selective Serotonin Reuptake Inhibitors; D000069470:Venlafaxine Hydrochloride