title: [A case of miliary tuberculosis with brain tuberculoma, following intraocular tuberculosis].
abstract: A 52-year-old woman with visual loss of her left eye consulted a ophthalmology clinic. She was conducted left vitrectomy and administered corticosteroid under the diagnosis of uveitis of unknown cause. But her visual acuity was not improved. Although re-surgery was planned, pus retention was found in her left eye. After her left eye was resected, fever and general malaise appeared suddenly. Her chest X-ray film revealed diffuse micronodular opacities. Acid-fast bacilli were detected from her sputum and identified to be Mycobacterium tuberculosis. She was diagnosed miliary tuberculosis, and then antituberculous chemotherapy consisting of 4 drugs was started. Granulomatous inflammation destructing retina and numerous acid-fact bacilli were found in histologic examination of the resected eye. This case was thought to be miliary tuberculosis disseminated from intraocular tuberculosis. After 2 months of therapy, neurologic symptoms which might be caused by brain tuberucloma appeared and deteriorated rapidly. But by adding corticosteroid to antituberculous therapy, symptoms were diminished gradually.
authors.affiliation: Department of Pulmonary Medicine, Kobe City General Hospital, Japan.
authors.forename: S
authors.initials: S
authors.lastname: Takakura
authors.forename: E
authors.initials: E
authors.lastname: Tanaka
authors.forename: T
authors.initials: T
authors.lastname: Kimoto
authors.forename: I
authors.initials: I
authors.lastname: Watanabe
authors.forename: H
authors.initials: H
authors.lastname: Matsumoto
authors.forename: K
authors.initials: K
authors.lastname: Tsuyuguchi
authors.forename: A
authors.initials: A
authors.lastname: Niimi
authors.forename: K
authors.initials: K
authors.lastname: Suzuki
authors.forename: R
authors.initials: R
authors.lastname: Amitani
authors.forename: F
authors.initials: F
authors.lastname: Kuze
mesh_terms: D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D000995:Antitubercular Agents / Q000008:administration & dosage; D001623:Betamethasone / Q000008:administration & dosage; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D008875:Middle Aged; D016862:Tuberculoma, Intracranial / Q000188:drug therapy / Q000209:etiology*; D014391:Tuberculosis, Miliary / Q000188:drug therapy / Q000209:etiology*; D014392:Tuberculosis, Ocular / Q000150:complications* / Q000188:drug therapy
chemical_list: D000893:Anti-Inflammatory Agents; D000995:Antitubercular Agents; D001623:Betamethasone