[Functional characteristics of foot skin mechanoreceptors and afferent nerve fibers of the sciatic nerve after central axotomy of sensory neurons].
The activity of mechanoreceptors was studied in normal rats' hindfoot and compared with that of rhizotomised animals. Evoked nerve impulses were recorded from afferent fibres of the n.tibialis. A possible autonomous functioning of decentralised mechanoreceptors, even though in an altered fashion, was shown. The registered shifts comprised a decrease in sensitivity to mechanical stimulation and lower adaptive properties. The findings suggest that the underlying mechanism involves a probable lack of trophic interaction leading to interruption of a link between the CNS and the peripheral nervous system.
Kolosova
L I
LI
Pavlov Institute of Physiology of the Russian Acad. Sci., St. Petersburg, Russia.
Akoev
G N
GN
Moiseeva
A B
AB
Riabchikova
O V
OV
D000344:Afferent Pathways / Q000502:physiology*; D000818:Animals; D019771:Axotomy; D004594:Electrophysiology; D005727:Ganglia, Spinal / Q000502:physiology*; D006614:Hindlimb / Q000502:physiology; D008297:Male; D008465:Mechanoreceptors / Q000502:physiology*; D009412:Nerve Fibers / Q000502:physiology*; D009475:Neurons, Afferent / Q000502:physiology* / Q000648:ultrastructure; D010812:Physical Stimulation; D051381:Rats; D017208:Rats, Wistar; D012584:Sciatic Nerve / Q000502:physiology* / Q000648:ultrastructure; D012879:Skin Physiological Phenomena
Issledovanie funktsional'nykh kharakteristik retseptorov kozhi stopy i afferentnykh nervnykh volokon sedalishchnogo nerva krysy posle tsentral'noĭ aksotomii sensornykh neĭronov.