Folic and folinic acid supplementation reduces methotrexate gastrointestinal side effects in rheumatoid arthritis.
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Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232-4500, USA.
D018501:Antirheumatic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D005492:Folic Acid / Q000008:administration & dosage / Q000627:therapeutic use*; D005767:Gastrointestinal Diseases / Q000139:chemically induced / Q000517:prevention & control*; D006801:Humans; D002955:Leucovorin / Q000008:administration & dosage / Q000627:therapeutic use*; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D016032:Randomized Controlled Trials as Topic
D018501:Antirheumatic Agents; D005492:Folic Acid; D002955:Leucovorin; D008727:Methotrexate