Binding, gating, affinity and efficacy: the interpretation of structure-activity relationships for agonists and of the effects of mutating receptors.
Colquhoun
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University College London.
D000494:Allosteric Regulation; D000818:Animals; D004252:DNA Mutational Analysis; D004305:Dose-Response Relationship, Drug; D019204:GTP-Binding Proteins / Q000378:metabolism; D006801:Humans; D015640:Ion Channel Gating; D007473:Ion Channels / Q000819:agonists / Q000235:genetics; D011487:Protein Conformation; D011956:Receptors, Cell Surface / Q000819:agonists* / Q000235:genetics*; D016194:Receptors, N-Methyl-D-Aspartate / Q000235:genetics; D013329:Structure-Activity Relationship
D007473:Ion Channels; D011956:Receptors, Cell Surface; D016194:Receptors, N-Methyl-D-Aspartate; D019204:GTP-Binding Proteins