Studies on pyrazine derivatives. XXXII. Synthesis and tuberculostatic activity of acetylpyrazine thiosemicarbazone derivatives.
Syntheses of 4-N-substituted thiosemicarbazoic acetylpyrazine derivatives have been described. The in vitro microbiological investigations of the 25 synthesized compound were carried out.
Milczarska
B
B
Department of Organic Chemistry, Medical University of Gdańsk, Poland.
Foks
H
H
Trapkowski
Z
Z
Milzyńska-Kołaczek
A
A
Janowiec
M
M
Zwolska
Z
Z
Andrzejczyk
Z
Z
D000995:Antitubercular Agents / Q000138:chemical synthesis* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009169:Mycobacterium tuberculosis / Q000187:drug effects; D011719:Pyrazines / Q000138:chemical synthesis* / Q000494:pharmacology; D013882:Thiosemicarbazones / Q000138:chemical synthesis* / Q000494:pharmacology
D000995:Antitubercular Agents; D011719:Pyrazines; D013882:Thiosemicarbazones