[Response of respiratory muscles to microinjections of acetylcholine and propranolol into the rat solitary nucleus].
Unilateral microinjections of acetylcholine into the rat solitary tract nucleus evoked inhibitory effects in electrical activity of symmetrical portions of the diaphragm and external intercostal muscles. Administration of propranolol exerted excitatory respiratory responses. The findings suggest participation of cholin- and noradrenergic systems in inhibitory mechanisms of respiratory control. Different roles of the right and left solitary tract nuclei in their involvement in formation of efferent impulses to bilateral inspiratory muscles, are discussed.
Sergeeva
L I
LI
State University, Samara, Russia.
Vediasova
O A
OA
Krasnov
D G
DG
D000109:Acetylcholine / Q000494:pharmacology / Q000502:physiology*; D000319:Adrenergic beta-Antagonists / Q000494:pharmacology*; D000818:Animals; D004525:Efferent Pathways / Q000502:physiology; D004576:Electromyography; D007839:Functional Laterality / Q000502:physiology; D008845:Microinjections; D009046:Motor Neurons / Q000502:physiology; D009638:Norepinephrine / Q000502:physiology*; D011433:Propranolol / Q000494:pharmacology*; D051381:Rats; D012132:Respiratory Muscles / Q000187:drug effects / Q000294:innervation / Q000502:physiology*; D017552:Solitary Nucleus / Q000187:drug effects / Q000502:physiology*
D000319:Adrenergic beta-Antagonists; D011433:Propranolol; D000109:Acetylcholine; D009638:Norepinephrine
Reaktsii inspiratornykh myshts u krys pri mikroin''ektsiiakh atsetilkholina i propranolola v iadro solitarnogo trakta.