Delayed delivery of multiple gestations: maternal and neonatal outcomes.
OBJECTIVE
The study's aims were to compare neonatal outcomes and to describe maternal complications in patients who underwent delayed delivery of twins or triplets in a preterm gestation.


METHODS
A retrospective review was performed on 5 sets of twins and 2 sets of triplets. Maternal morbidity was described. Neonatal outcomes were compared in the initial and subsequent delivery groups.


RESULTS
The percentage of surviving firstborns was 57%, compared with 78% among latter-born infants. The average gestational age of the initial delivery group was 22.6 weeks (18.9-24.7 weeks); gestational age was 27.4 weeks (19.3-37.9 weeks) for the subsequent group (P <.05), a difference of 32.6 days. The average weight gain was 556.1 g. Serious neonatal complications were less frequent among the subsequently delivered siblings (P <.05), and the mean difference in neonatal hospital stay was 77.3 days, with a range of 62.5 to 139.8 (P <.5). Adverse maternal outcomes were represented by 3 patients with abruptio placentae and 3 patients with intra-amniotic infection, 2 of whom had positive blood culture results.


CONCLUSIONS
On the basis of our experience with 7 multifetal pregnancies, delayed delivery has been demonstrated to increase the likelihood of survival and decrease morbidity among the latter-born siblings. Despite the risk of complications, these data support therapeutic interventions aimed at delayed delivery of subsequent fetuses in cases with the potential for significant morbidity and mortality.
Kalchbrenner
M A
MA
Maternal-Fetal Medicine Department, Rockford Regional Perinatal Center, University of Illinois, Rockford, IL 61103, USA.
Weisenborn
E J
EJ
Chyu
J K
JK
Kaufman
H K
HK
Losure
T A
TA
D015331:Cohort Studies; D036861:Delivery, Obstetric; D005260:Female; D017048:Health Care Costs; D006801:Humans; D015994:Incidence; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology; D007902:Length of Stay; D008429:Maternal Welfare; D007744:Obstetric Labor Complications / Q000453:epidemiology; D011247:Pregnancy; D011256:Pregnancy Outcome; D011272:Pregnancy, Multiple; D012189:Retrospective Studies; D013997:Time Factors; D014310:Triplets; D014427:Twins; D015430:Weight Gain / Q000502:physiology