Pseudoanaplastic chondromyxoid fibroma.
A 19-year-old man presented with a chondromyxoid fibroma of the distal phalanx of the great toe that was originally diagnosed as osteosarcoma rather than "dedifferentiated" chondrosarcoma. Radiographs showed a large, expansive, and calcified tumor of the distal phalanx. Although the tumor had the architectural and matrix patterns of a chondromyxoid fibroma, high-power examination demonstrated that the lesion had such severe nuclear pleomorphism that it was mistaken for high-grade sarcoma. The purpose of this report is to present the criteria used to differentiate a benign pseudoanaplastic chondromyxoid fibroma from chondrogenic high-grade sarcomas.
Bahk
W J
WJ
Orthopaedic Oncology, Orthopaedic Hospital, Los Angeles, CA, USA.
Mirra
J M
JM
Sohn
K R
KR
Shin
D S
DS
D000328:Adult; D000708:Anaplasia / Q000473:pathology; D001859:Bone Neoplasms / Q000175:diagnosis / Q000473:pathology*; D002804:Chondroblastoma / Q000175:diagnosis / Q000473:pathology*; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D012509:Sarcoma / Q000175:diagnosis / Q000473:pathology