Idiopathic pulmonary fibrosis and cyclosporine: a lesson from single-lung transplantation.
Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and therapeutic options are limited with a 5-year survival of less than 50%. This report includes a case of histologically confirmed IPF in a patient whose native lung showed objective improvement as measured by high-resolution CT while he was receiving cyclosporine-based immunosuppressive therapy after single-lung transplantation.
Lok
S S
SS
North West Lung Centre, Wythenshawe Hospital, Manchester, United Kingdom.
Smith
E
E
Doran
H M
HM
Sawyer
R
R
Yonan
N
N
Egan
J J
JJ
D016572:Cyclosporine / Q000627:therapeutic use*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008168:Lung / Q000000981:diagnostic imaging / Q000473:pathology; D016040:Lung Transplantation; D008297:Male; D008875:Middle Aged; D011658:Pulmonary Fibrosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery* / Q000628:therapy; D011859:Radiography
D007166:Immunosuppressive Agents; D016572:Cyclosporine