Pure yolk sac tumor of the ovary with mosaic 45X/46X + mar Turner's syndrome with a Y-chromosomal fragment.
A pure yolk sac tumor (endodermal sinus tumor) of the dysgenetic gonad developed in a 23-year-old woman whose karyotype was mosaic 45X/46X + mar Turner's syndrome is reported. Molecular biological studies showed that the patient's DNA contained a fragment of Y chromosome. This case seems to be extremely rare case of developing a pure yolk sac tumor in a patient with mosaic Turner syndrome with a Y-chromosomal fragment.
Ito
K
K
Department of Obstetrics and Gynecology, Chiba University School of Medicine, Japan.
Kawamata
Y
Y
Osada
H
H
Ijichi
M
M
Takano
H
H
Sekiya
S
S
D000328:Adult; D004247:DNA / Q000032:analysis; D004273:DNA, Neoplasm / Q000032:analysis; D018240:Endodermal Sinus Tumor / Q000150:complications / Q000235:genetics* / Q000473:pathology; D005260:Female; D006801:Humans; D007621:Karyotyping; D009030:Mosaicism; D010051:Ovarian Neoplasms / Q000150:complications / Q000235:genetics* / Q000473:pathology; D016133:Polymerase Chain Reaction; D014424:Turner Syndrome / Q000150:complications / Q000235:genetics*; D014998:Y Chromosome
D004273:DNA, Neoplasm; D004247:DNA