Methods for the determination of organochlorine pesticide residues in human serum.
The effectiveness of solid-phase extraction with Florisil for the determination of 12 organochlorine pesticide residues from human serum was examined. Recoveries greater than 84% and coefficients of variation better than 19% were obtained. Others methods, such as column partition and matrix solid-phase dispersion, were compared. The better method provides quantification limits ranging from 1.08 microg/l for gamma-HCH and 37.5 microg/l for p,p'-DDT when capillary gas-liquid chromatography with electron-capture detection is used for the final determination.
Lino
C M
CM
Laboratory of Bromatology and Hydrology, Faculty of Pharmacy, University of Coimbra, Portugal.
Azzolini
C B
CB
Nunes
D S
DS
Silva
J M
JM
da Silveira
M I
MI
D000096:Acetone; D002849:Chromatography, Gas / Q000379:methods*; D006586:Hexanes; D006801:Humans; D007202:Indicators and Reagents; D007306:Insecticides / Q000097:blood*; D017633:Magnesium Silicates; D008752:Methylene Chloride; D010573:Pesticide Residues / Q000097:blood*; D012680:Sensitivity and Specificity
D006586:Hexanes; D007202:Indicators and Reagents; D007306:Insecticides; D017633:Magnesium Silicates; D010573:Pesticide Residues; C005013:Florisil; D000096:Acetone; C026385:n-hexane; D008752:Methylene Chloride