Cerebellopontine angle lymphoma: a case report and review of the literature.
BACKGROUND
Although malignant lymphomas of the central nervous system have been reported to be increasing in frequency, cerebellopontine (CP) angle lymphoma is rare and only 13 cases have been reported previously in the literature.


METHODS
A 63-year-old woman had progressive dizziness and nausea for 2 months. Computed tomography scanning and magnetic resonance imaging (MRI) revealed a mass lesion in the left CP angle, that was compressing the lateral-dorsal aspect of the pons and the fourth ventricle. This tumor was avascular on angiography. The tumor was surgically removed through a left lateral suboccipital approach. It was considered to arise from the subarachnoid space of the CP angle cistern. For some reason, the histologic diagnosis was not definitively made, and therefore radiation therapy was not planned. The tumor recurred within 50 days after the tumor excision. Surgical excision of the recurrent tumor was performed again. The histologic diagnosis was B-cell type malignant lymphoma. Radiation therapy was performed. In the 27 months since irradiation, a recurrent tumor has not been detected on MRI.


CONCLUSIONS
Although erosion and expansion of the internal auditory canal suggest an acoustic neurinoma, CP angle lymphoma can, in rare circumstances, erode the internal auditory canal. There are three distinct patterns in which malignant lymphomas occupy the CP angle: (1) an extra-axial CP angle lymphoma, (2) an intra-axial lymphoma extending to the CP angle, and (3) a leptomeningeal lymphoma presenting as a CP angle lesion. Although malignant lymphomas rarely occupy the CP angle, it should be considered in the differential diagnosis of CP angle tumors. It is desirable to obtain a frozen section in all CP angle tumors during surgery to identify the tumor, because aggressive removal is not necessary, but radiation therapy should additionally be performed for malignant lymphomas.
Nishimura
T
T
Kochi Cerebrovascular Research Institute, Uchida Neurosurgery Clinic, Kochi-City, Japan.
Uchida
Y
Y
Fukuoka
M
M
Ono
Y
Y
Kurisaka
M
M
Mori
K
K
D002528:Cerebellar Neoplasms / Q000175:diagnosis* / Q000601:surgery; D002530:Cerebellopontine Angle / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008223:Lymphoma / Q000175:diagnosis* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012086:Reoperation; D014057:Tomography, X-Ray Computed