title: Systemic bone-seeking radionuclides for palliation of painful osseous metastases: current concepts.
abstract: Bone metastases require multidisciplinary treatment, the primary goal of which is to relieve pain and improve quality of life. Among the options available, bone-seeking radioisotopes are attractive because they can treat several symptomatic metastases simultaneously. This therapy may have antitumor efficacy in addition to analgesic properties. Although the ultimate place of systemic radionuclides in the treatment of bone metastases has not been firmly established, some patients clearly benefit from these modalities.
authors.affiliation: Oncology Services, North Oakland Medical Centers, Pontiac, MI, USA.
authors.forename: W C
authors.initials: WC
authors.lastname: Mertens
authors.forename: L A
authors.initials: LA
authors.lastname: Filipczak
authors.forename: E
authors.initials: E
authors.lastname: Ben-Josef
authors.forename: L P
authors.initials: LP
authors.lastname: Davis
authors.forename: A T
authors.initials: AT
authors.lastname: Porter
mesh_terms: D000700:Analgesics / Q000009:adverse effects / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy* / Q000556:secondary*; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D004359:Drug Therapy, Combination; D006801:Humans; D010146:Pain / Q000188:drug therapy*; D010166:Palliative Care / Q000379:methods*; D011868:Radioisotopes / Q000009:adverse effects / Q000627:therapeutic use*; D011877:Radionuclide Imaging
chemical_list: D000700:Analgesics; D011868:Radioisotopes