Association of excess sulfur intake and an increase in hydrogen sulfide concentrations in the ruminal gas cap of recently weaned beef calves with polioencephalomalacia.
During a 2-week period, 16 of 150 recently weaned calves developed signs of polioencephalomalacia (PEM). One calf was examined and treated at our veterinary teaching hospital and a necropsy was performed on a calf that died. During the peak of the outbreak, clinicians visited the ranch. Ruminal hydrogen sulfide (H2S) and blood thiamine concentrations were measured in 10 clinically normal penmates of PEM-affected calves. Ruminal H2S concentrations were high (> 0.695 mg/L [> 500 ppm]) in all cattle (mean, 12.19 mg/L [8,770 ppm]). All blood thiamine values were within the reference range. Within 12 hours after measurement of blood thiamine concentrations, 2 of the calves from which samples were obtained developed clinical signs of PEM. Dietary analysis revealed an estimated sulfur intake of 0.9% per calf on a dry-matter basis. Hay contributed most of this sulfur. In the investigation reported here, an outbreak of PEM was associated with high ruminal H2S concentrations and excess sulfur intake without evidence of thiamine deficiency.
Loneragan
G H
GH
Department of Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins 80523-1620, USA.
Gould
D H
DH
Callan
R J
RJ
Sigurdson
C J
CJ
Hamar
D W
DW
D000821:Animal Feed / Q000032:analysis; D000818:Animals; D001921:Brain / Q000473:pathology; D002417:Cattle; D002418:Cattle Diseases / Q000209:etiology* / Q000473:pathology; D004678:Encephalomalacia / Q000209:etiology / Q000473:pathology / Q000662:veterinary*; D005260:Female; D006862:Hydrogen Sulfide / Q000032:analysis*; D008297:Male; D018482:Muscle, Skeletal / Q000473:pathology; D006109:Poaceae / Q000737:chemistry; D012417:Rumen / Q000737:chemistry*; D013455:Sulfur / Q000008:administration & dosage* / Q000009:adverse effects / Q000032:analysis; D014867:Water / Q000032:analysis; D014886:Weaning
D014867:Water; D013455:Sulfur; D006862:Hydrogen Sulfide