title: Survey of anaerobic susceptibility patterns: a French multicentre study.
abstract: In 1996, the in vitro antibiotic susceptibility of 463 anaerobes was measured in five hospitals using the reference agar dilution method. None of the 209 B. fragilis group strains showed resistance to imipenem or ticarcillin-clavulanic acid. High resistance rates (29%) were observed for cefotetan and clindamycin. beta-Lactamase production was detected respectively in 64% of the Prevotella and 7% of the Fusobacterium strains. Because the same standardized methods were used for many years, the authors were able to evaluate the evolution of antibiotic resistance. Clindamycin resistance had increased within the B. fragilis group (from 14% in 1992 to 29% in 1996) and also among strains of clostridia (32%), P. acnes (18%) and Peptostreptococcus (28%). In the B. fragilis group multidrug resistance was unlikely to occur.
authors.affiliation: Chu de Nancy, France.
authors.forename: F
authors.initials: F
authors.lastname: Mory
authors.forename: A
authors.initials: A
authors.lastname: Lozniewski
authors.forename: S
authors.initials: S
authors.lastname: Bland
authors.forename: A
authors.initials: A
authors.lastname: Sedallian
authors.forename: G
authors.initials: G
authors.lastname: Grollier
authors.forename: F
authors.initials: F
authors.lastname: Girard-Pipau
authors.forename: M F
authors.initials: MF
authors.lastname: Paris
authors.forename: L
authors.initials: L
authors.lastname: Dubreuil
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001421:Bacteria, Anaerobic / Q000187:drug effects*; D001424:Bacterial Infections / Q000382:microbiology*; D001438:Bacteroidaceae / Q000187:drug effects; D004352:Drug Resistance, Microbial; D005602:France; D006095:Gram-Positive Cocci / Q000187:drug effects; D016987:Gram-Positive Rods / Q000187:drug effects; D006801:Humans; D008826:Microbial Sensitivity Tests
chemical_list: D000900:Anti-Bacterial Agents