title: [Investigations into the occurrence and the antibiotic susceptibility of gram negative anaerobes of the genera Bacteroides, Prevotella, Porphyromonas and Fusobacterium in specimens obtained from diseased animals].
abstract: From different samples of 247 diseased animals (cattle, sheep, goat, horse, pig, dog, cat, rodent, zoo-animals), 410 strains of gram-negative anaerobes were cultured. 297 isolates (72.4%) could be differentiated to the species level by using cultural-biochemical methods, gaschromatography and cell-wall-lipidanalysis. They belonged to 29 different species. For an additional 113 strains (27.6%) only the genus could be determined. Bacteria belonging to the genus Fusobacterium occurred with the highest isolation rates (36% of all strains) in the samples examined, followed by Bacteroides spp. (26.1%), Prevotella spp. (19.9%) and Prophyromonas spp. (17.8%). Fusobacterium necrophorum was the single species isolated most frequently. Antibiotic susceptibility tests by E-test were performed on 100 strains belonging to the the above mentioned genera. Of these strains 18% were resistant to penicillin and 20% to tetracycline. The resistant strains belonged mainly to the Bacteroides fragilis-group. Resistant rates to most other antimicrobial agents tested were Amoxicillin in combination with clavulanic acid: 1%, Chloramphenicol: 3%, Clindamycin:8%. All 100 selected strains proved to be susceptible to Metronidazol.
authors.affiliation: Institut für Mikrobiologie und Tierseuchen, Tierärztlichen Hochschule Hannover.
authors.forename: H
authors.initials: H
authors.lastname: Even
authors.forename: J
authors.initials: J
authors.lastname: Rohde
authors.forename: J
authors.initials: J
authors.lastname: Verspohl
authors.forename: M
authors.initials: M
authors.lastname: Ryll
authors.forename: G
authors.initials: G
authors.lastname: Amtsberg
mesh_terms: D000818:Animals; D000836:Animals, Zoo; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001439:Bacteroides / Q000187:drug effects / Q000302:isolation & purification; D002371:Cat Diseases / Q000382:microbiology; D002415:Cats; D002417:Cattle; D002418:Cattle Diseases / Q000382:microbiology; D004283:Dog Diseases / Q000382:microbiology; D004285:Dogs; D005673:Fusobacterium / Q000187:drug effects / Q000302:isolation & purification; D015511:Goat Diseases / Q000382:microbiology; D006041:Goats; D006089:Gram-Negative Anaerobic Bacteria / Q000187:drug effects* / Q000302:isolation & purification; D016905:Gram-Negative Bacterial Infections / Q000382:microbiology / Q000662:veterinary*; D006734:Horse Diseases / Q000382:microbiology; D006736:Horses; D008826:Microbial Sensitivity Tests; D017861:Porphyromonas / Q000187:drug effects / Q000302:isolation & purification; D018720:Prevotella / Q000187:drug effects / Q000302:isolation & purification; D012376:Rodent Diseases / Q000382:microbiology; D012377:Rodentia; D012756:Sheep; D012757:Sheep Diseases / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents
vernacular_title: Untersuchungen zum Vorkommen und zur Antibiotikaresistenz gramnegativer Anaerobier der Gattungen Bacteroides, Prevotella, Porphyromonas und Fusobacterium im Untersuchungsmaterial erkrankter Tiere.