title: Blood pressure in children exposed prenatally to cocaine.
abstract: Prenatal exposure to cocaine may alter autonomic nervous system function resulting in hypertension. Blood pressure was measured oscillometrically in a convenience sample of cocaine-exposed (n = 32) and nonexposed (n = 23) children, aged 8 to 26 months, by examiners unaware of exposure status. The exposed and nonexposed groups did not differ in systolic pressure (mean +/- SD 102.3 +/- 9.9 mmHg vs 119.1 +/- 19.4). Prenatal exposure to cocaine does not appear to be associated with elevated blood pressure in young children.
authors.affiliation: Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
authors.forename: R
authors.initials: R
authors.lastname: Needlman
authors.forename: D A
authors.initials: DA
authors.lastname: Frank
authors.forename: H
authors.initials: H
authors.lastname: Cabral
authors.forename: M
authors.initials: M
authors.lastname: Mirochnick
authors.forename: C
authors.initials: C
authors.lastname: Kwon
authors.forename: B
authors.initials: B
authors.lastname: Zuckerman
mesh_terms: D001341:Autonomic Nervous System / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D002675:Child, Preschool; D003042:Cocaine / Q000009:adverse effects*; D005260:Female; D005315:Fetal Diseases / Q000139:chemically induced; D005333:Fetus / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000139:chemically induced*; D007223:Infant; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced*; D011297:Prenatal Exposure Delayed Effects
chemical_list: D003042:Cocaine