title: Diagnostic quality in hysterosalpingography. Comparison between iodixanol and iotrolan.
abstract: OBJECTIVE
  To compare the diagnostic quality and adverse events of the water-soluble, non-ionic, iso-osmolar, dimeric contrast media iodixanol and iotrolan in hysterosalpingography (HSG).
  
  
  METHODS
  One hundred and twenty patients participated in a double-blind randomized parallel-group phase-III study. Questionnaires and patient interviews were used. Diagnostic quality was assessed using a visual analogue scale and the quality in specific regions was rated using a categorical scale.
  
  
  RESULTS
  Overall diagnostic quality was equal for the two groups. There was no statistically significant difference between the two groups in diagnostic quality in the specific regions of interest. No differences between the contrast media were found with regard to adverse events.
  
  
  CONCLUSIONS
  Both contrast media provided images of high diagnostic quality in HSG.
authors.affiliation: Department of Radiology, Esbjerg Central Hospital, Denmark.
authors.forename: S
authors.initials: S
authors.lastname: Lindequist
authors.forename: F
authors.initials: F
authors.lastname: Rasmussen
authors.forename: H H
authors.initials: HH
authors.lastname: Madsen
authors.forename: A
authors.initials: A
authors.lastname: Naeser
authors.forename: K
authors.initials: K
authors.lastname: Bjartveit
authors.forename: D T
authors.initials: DT
authors.lastname: Kristoffersen
authors.forename: A J
authors.initials: AJ
authors.lastname: Klaveness
mesh_terms: D003287:Contrast Media / Q000008:administration & dosage*; D004311:Double-Blind Method; D005187:Fallopian Tubes / Q000473:pathology*; D005260:Female; D006801:Humans; D007047:Hysterosalpingography / Q000379:methods / Q000592:standards; D007247:Infertility, Female / Q000000981:diagnostic imaging*; D007267:Injections; D015203:Reproducibility of Results; D012449:Safety; D011795:Surveys and Questionnaires; D014283:Triiodobenzoic Acids / Q000008:administration & dosage; D014599:Uterus / Q000473:pathology*
chemical_list: D003287:Contrast Media; D014283:Triiodobenzoic Acids; C033300:iotrolan; C044834:iodixanol