Heterogeneity of the PorB protein in serotype 22 Neisseria meningitidis.
The genetic diversity of porB genes from meningococcal isolates characterized as serotype 22 was investigated by gene sequencing. This procedure identified seven distinct porB sequences, demonstrating variation in the PorB protein recognized by the serotype 22 monoclonal antibody. This is consistent with the genetic heterogeneity of serotype 22 meningococci reported previously.
Urwin
R
R
Wellcome Trust Centre for the Epidemiology of Infectious Disease, Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom.
Fox
A J
AJ
Musilek
M
M
Kriz
P
P
Maiden
M C
MC
D000595:Amino Acid Sequence; D001425:Bacterial Outer Membrane Proteins / Q000737:chemistry / Q000235:genetics* / Q000276:immunology; D008969:Molecular Sequence Data; D009345:Neisseria meningitidis / Q000737:chemistry / Q000235:genetics* / Q000276:immunology; D018272:Porins; D012703:Serotyping
D001425:Bacterial Outer Membrane Proteins; D018272:Porins; C057699:porin protein, Neisseria