title: [Efficacy of lomefloxacin and ofloxacin in complex therapy of infections in patients with burns].
abstract: The experience with lomefloxacin and ofloxacin respectively in the complex therapy of 26 and 40 patients with burns is described. The drugs were shown to be highly active in the treatment of burn wound infections and infectious complications of burn disease. The clinical efficacy of lomefloxacin and ofloxacin amounted to 88 and 77.5 per cent and the bacteriological efficacy amounted to 81 and 80 per cent respectively.
authors.affiliation: A.V. Vishnevsky Institute of Surgery, Russian Academy of Medical Sciences, Moscow.
authors.forename: M G
authors.initials: MG
authors.lastname: Krutikov
authors.forename: A A
authors.initials: AA
authors.lastname: Alekseev
authors.forename: A E
authors.initials: AE
authors.lastname: Bobrovnikov
authors.forename: I A
authors.initials: IA
authors.lastname: Grishina
authors.forename: L V
authors.initials: LV
authors.lastname: Elagina
authors.forename: G N
authors.initials: GN
authors.lastname: Izotova
authors.forename: V P
authors.initials: VP
authors.lastname: Iakovlev
mesh_terms: D000293:Adolescent; D000328:Adult; D000890:Anti-Infective Agents / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D002056:Burns / Q000188:drug therapy* / Q000382:microbiology; D004352:Drug Resistance, Microbial; D018432:Drug Resistance, Multiple; D005260:Female; D024841:Fluoroquinolones; D006801:Humans; D008297:Male; D008875:Middle Aged; D015242:Ofloxacin / Q000008:administration & dosage / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D011552:Pseudomonas Infections / Q000188:drug therapy* / Q000382:microbiology; D015363:Quinolones / Q000009:adverse effects / Q000493:pharmacokinetics / Q000494:pharmacology / Q000627:therapeutic use*; D013203:Staphylococcal Infections / Q000188:drug therapy* / Q000382:microbiology
chemical_list: D000890:Anti-Infective Agents; D024841:Fluoroquinolones; D015363:Quinolones; D015242:Ofloxacin; C053091:lomefloxacin
vernacular_title: Effektivnost' lomefloksatsina i ofloksatsina v kompleksnom lechenii infektsiĭ u obozhzhennykh.