Generalized infantile myofibromatosis in a patient with Turner's syndrome: a trial of interferon-alpha.
A patient with Turner's syndrome was found to have generalized infantile myofibromatosis with visceral involvement at birth. The infant was treated with interferon-alpha because of the size of the lesions. Two months after treatment, the lesions appeared to have decreased in size and showed evidence of maturation with decreased apoptosis on histologic examination. Interferon-alpha treatment might induce regression of myofibromatosis.
Savaşan
S
S
Barbara Ann Karmanos Cancer Institute, Detroit, Michigan, USA.
Fulgenzi
L A
LA
Rabah
R
R
Mohamed
A N
AN
Ravindranath
Y
Y
D003952:Diagnostic Imaging; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007279:Injections, Subcutaneous; D000077190:Interferon alpha-2; D016898:Interferon-alpha / Q000008:administration & dosage*; D018224:Myofibromatosis / Q000175:diagnosis / Q000235:genetics / Q000628:therapy*; D011994:Recombinant Proteins; D014424:Turner Syndrome / Q000175:diagnosis / Q000235:genetics / Q000628:therapy*
D000077190:Interferon alpha-2; D016898:Interferon-alpha; D011994:Recombinant Proteins