[13C-urea breath test as diagnostic method in Helicobacter pylori infection].
We have evaluated a 13C-urea breath test for the diagnosis of Helicobacter pylori infection. The 13C-test was analyzed with isotope-selective nondispersive infrared spectrometry and compared with a 14C-urea breath test and the urease test in gastric mucosal biopsies. 46 patients were analyzed with breath tests; 23 patients were negative and 22 patients were positive with both methods. One patient was positive with the 14C-method and negative with the 13C-urea breath test. 61 patients were analyzed with the 13C-urea breath test and the urease test. 30 patients were negative and 30 patients were positive with both methods, whereas one patient with a negative urease test had a positive breath test. 13C-urea breath test analyzed with isotope-selective non-dispersive infrared spectrometry is a fast, simple, non-radioactive, non-invasive, convenient and reliable method for the diagnosis of Helicobacter pylori infection.
Dahlberg
M
M
Sentrallaboratoriet, Aker sykehus, Oslo.
Schjønsby
H
H
D000328:Adult; D000368:Aged; D001944:Breath Tests; D002247:Carbon Isotopes; D004381:Duodenal Ulcer / Q000382:microbiology; D004415:Dyspepsia / Q000382:microbiology*; D005260:Female; D005756:Gastritis / Q000382:microbiology*; D016481:Helicobacter Infections / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D010437:Peptic Ulcer / Q000382:microbiology*; D013276:Stomach Ulcer / Q000382:microbiology; D014508:Urea / Q000032:analysis*
D002247:Carbon Isotopes; D014508:Urea
13C-urea-pusteprøve som diagnostisk metode ved Helicobacter pylori-infeksjon.