title: Glucosamine in osteoarthritis and gastrointestinal disorders: an exemplar of the need for a paradigm shift.
abstract: Glucosamine, after a latent period, is rapidly developing a position in the treatment of osteoarthritis, as well as a potential therapeutic place in wound healing and gastrointestinal disorders. Although recognized for a great many years, the association of gastrointestinal disorders and arthritis has been looked on as an unexplained oddity. Could this be indicative of a common etiology in the rate-limiting production of glucosamine? Could diverse presentations and pathology be due to a common-stem biochemical defect?
authors.affiliation: Brampton Pain Clinic, Bramalea, Ontario, Canada.
authors.forename: A L
authors.initials: AL
authors.lastname: Russell
mesh_terms: D000818:Animals; D005944:Glucosamine / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000188:drug therapy / Q000209:etiology; D010003:Osteoarthritis / Q000188:drug therapy* / Q000209:etiology; D014945:Wound Healing / Q000187:drug effects
chemical_list: D005944:Glucosamine