Radiographic and histologic patterns of calcification in chondromyxoid fibroma.
OBJECTIVE
To evaluate the frequency of radiologic and histologic manifestations of matrix calcification in chondromyxoid fibromas.


METHODS
Forty-four cases of chondromyxoid fibroma were reviewed. The age range of the patients was 3-70 years (average 29 years).


RESULTS
Calcification was found microscopically in 15 cases (34.1%). In five cases (12.5%) it was demonstrated on plain films or CT. The age range of the patients with microscopic evidence of calcified matrix was 14-70 years (mean 46 years), while that of the patients with non-calcified lesions was 3-59 years (average 21 years). All but two of the patients who showed microscopic calcification in the tumors were over 40 years of age. Four microscopic patterns of calcification were observed: coarse granular, circumscribed, trabecular, and "chicken-wire."


CONCLUSIONS
Calcification in chondromyxoid fibroma was found more frequently than in previously reported studies. There was a tendency for this phenomenon to occur in the tumors of older patients, particularly those over 40 years old, and in chondromyxoid fibromas situated in flat bones, including ribs.
Yamaguchi
T
T
Department of Orthopaedic Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, Bronx, NY 10467-2490, USA.
Dorfman
H D
HD
D000293:Adolescent; D000328:Adult; D000368:Aged; D001859:Bone Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology*; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000473:pathology; D002114:Calcinosis / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D002804:Chondroblastoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology*; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011859:Radiography