title: Optimal selection and preparation of fresh frozen corticocancellous allografts for cervical interbody spinal fusion.
abstract: METHODS
  Iliac crest corticocancellous allografts for anterior interbody fusion were harvested from six cadavers. The grafts were cut sequentially from left and right crests and randomly assigned to tricortical or bicortical preparations. Their compression strengths then were determined and compared by matched pair analysis.
  
  
  OBJECTIVE
  To quantify the failure strength of the grafts from different iliac locations and determine the optimal type of preparation of the grafts for anterior interbody fusion.
  
  
  BACKGROUND
  Iliac crest corticocancellous autografts and allografts commonly are used for interbody cervical fusions. However, graft strengths for specific sites have not been determined fully.
  
  
  METHODS
  Six paired, fresh frozen, iliac crests were sectioned using a customized miter box into multiple 1-cm-thick grafts 1.5 cm in depth to simulate cervical interbody grafts. The left and right sides of each pair were randomly assigned to tricortical and bicortical preparations. The samples were tested by applying a compressive load to failure using a specialized fixture to simulate vertebral body loading.
  
  
  RESULTS
  The grafts closer to the anterosuperior iliac spine had significantly higher failure loads and failure strengths than those closer to the posterosuperior iliac spine. The strengths of the bicortical grafts were 72 +/- 14% of the strengths of the tricortical grafts (P < 0.001).
  
  
  CONCLUSIONS
  Anterior iliac crest grafts were stronger in compression, even after removal of one cortical surface, than posterior iliac crest grafts.
authors.affiliation: Musculoskeletal Research Center, Hospital for Joint Diseases Orthopedic Institute, New York, New York, USA.
authors.forename: F J
authors.initials: FJ
authors.lastname: Kummer
authors.forename: D
authors.initials: D
authors.lastname: Chen
authors.forename: J M
authors.initials: JM
authors.lastname: Spivak
mesh_terms: D000328:Adult; D015519:Bone Density; D016025:Bone Transplantation / Q000379:methods*; D002102:Cadaver; D002574:Cervical Vertebrae / Q000601:surgery*; D015925:Cryopreservation; D005260:Female; D006801:Humans; D007085:Ilium / Q000637:transplantation*; D008297:Male; D013123:Spinal Fusion / Q000379:methods*; D013314:Stress, Mechanical; D013997:Time Factors; D009927:Tissue and Organ Procurement; D014184:Transplantation, Homologous; D016474:Weight-Bearing