title: Two factors of experienced deficits in schizophrenia and their relationships with positive, negative, and depressive symptoms.
abstract: Eighty inpatients and 20 outpatients with ICD-10 schizophrenia were assessed with the Manchester Scale (MS) and the scale for the assessment of Subjective Experience of Deficits in Schizophrenia (SEDS). A factor analysis on MS scores yielded a three-factor solution: negative symptoms, positive symptoms, and anxious-depressive factor. On the other hand, a factor analysis on SEDS scores provided a seven-factor solution. The first factor, "awareness of social incompetence (ASI)," positively correlated with the anxious-depressive factor. ASI may reflect a negative cognitive attitude of persons who easily become depressive. The second factor, "subjective cognitive disturbance (SCD)," positively correlated with the positive-symptoms factor. SCD might represent a subtle disturbance, which can also produce positive symptoms. We found no factor on SEDS that correlated with the negative-symptoms factor. It was noted that a selection and comparison of items and the cultural background of subjects should be considered.
authors.affiliation: Department of Neuropsychiatry, School of Medicine, Tokyo Medical and Dental University, Japan.
authors.forename: A
authors.initials: A
authors.lastname: Iwawaki
authors.forename: K
authors.initials: K
authors.lastname: Narushima
authors.forename: K
authors.initials: K
authors.lastname: Ota
authors.forename: T
authors.initials: T
authors.lastname: Okura
authors.forename: K
authors.initials: K
authors.lastname: Tsuchiya
authors.forename: A
authors.initials: A
authors.lastname: Takashima
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D014150:Antipsychotic Agents / Q000627:therapeutic use; D001008:Anxiety Disorders / Q000150:complications / Q000175:diagnosis / Q000523:psychology; D002746:Chlorpromazine / Q000627:therapeutic use; D003866:Depressive Disorder / Q000150:complications / Q000175:diagnosis / Q000523:psychology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D012565:Schizophrenic Psychology
chemical_list: D014150:Antipsychotic Agents; D002746:Chlorpromazine