Acute lung injury after inhalation of water-proofing spray while smoking a cigarette.
A 34-year-old Japanese woman developed acute lung injury soon after inhaling a water-proofing spray which she applied onto her ski suit while smoking a cigarette at the same time. She initially demonstrated arterial hypoxemia (PaO2 = 59 mm Hg) and ground-glass opacities in both lung fields on the CT scan, which both returned to normal without any medication. Several water-proofing sprays, which are easily obtainable in Japan, contain 1,1,1-trichloroethane, liquefied petroleum gas and fluoride resin. Although these components have not been reported to be toxic to the lung yet, high concentrations of these components and/or the pyrolytic products of fluoride resin may have caused acute lung injury in this case.
Jinn
Y
Y
Second Department of Internal Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Akizuki
N
N
Ohkouchi
M
M
Inase
N
N
Ichioka
M
M
Marumo
F
F
D000208:Acute Disease; D000328:Adult; D003020:Clothing; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000139:chemically induced; D008171:Lung Diseases / Q000139:chemically induced*; D010578:Petroleum / Q000506:poisoning; D012907:Smoking / Q000009:adverse effects*; D012997:Solvents / Q000506:poisoning*; D014240:Trichloroethanes / Q000506:poisoning*
D010578:Petroleum; D012997:Solvents; D014240:Trichloroethanes; C024566:1,1,1-trichloroethane