The distribution of calcitonin gene-related peptide in gastric vagal circuit of rats.
In the present study, we performed the retrograde tracing method using the neurotropic pseudorabies virus bartha strain (PRV-Ba) and immunohistochemistry against CGRP, to identify whether CGRP exists in the gastric monosynaptic vagal circuit between dorsal motor nucleus of vagus nerve (DMV) and nucleus tractus solitarius (NTS). At the results, PRV immunoreactive neurons were found in both DMV and NTS. However, CGRP-immunoreactive cells were present only in NTS, which contained no double-labeled neurons for PRV and CGRP. These results suggest that CGRP may not have a neuronal function in gastric vagal circuit of rat.
Lee
H S
HS
Department of Anatomy, College of Veterinary Medicine, Seoul National University, Suwon, Republic of Korea.
Lee
I S
IS
Kang
T C
TC
Seo
J
J
Lee
B H
BH
D000818:Animals; D001370:Axonal Transport; D015740:Calcitonin Gene-Related Peptide / Q000032:analysis*; D011558:Herpesvirus 1, Suid; D007150:Immunohistochemistry; D009474:Neurons / Q000166:cytology* / Q000502:physiology; D051381:Rats; D017207:Rats, Sprague-Dawley; D017552:Solitary Nucleus / Q000033:anatomy & histology* / Q000166:cytology / Q000502:physiology; D013270:Stomach / Q000294:innervation; D013569:Synapses / Q000648:ultrastructure; D014630:Vagus Nerve / Q000033:anatomy & histology* / Q000166:cytology / Q000502:physiology
D015740:Calcitonin Gene-Related Peptide