Antagonistic effect of calcium, zinc and selenium against cadmium induced chromosomal aberrations and micronuclei in root cells of Hordeum vulgare.
The antagonistic effect of calcium (Ca2+), zinc (Zn2+) and selenium (Se4+) at different concentrations (10-2-10-6 M) against cadmium (Cd2+) induced genotoxic effects in root cells of Hordeum vulgare were studied. The results showed that 10-3-10-5 M could induce chromosomal aberrations and micronuclei formation. But in the treatment with 10-2-10-6 M of Ca2+, Zn2+ and Se4+ together with Cd2+ (10-3-10-5 M), respectively, the frequencies of chromosomal aberrations and micronuclei effectively decreased after 48 h of treatment. The treatment with 10-4-10-6 M of Ca2+ together with 10-4-10-5 M Cd2+, 10-6 M of Zn2+ together with 10-5 M Cd2+ and 10-6 M of Se4+ together with 10-5 M Cd2+ suggested rather obvious antagonistic effects. The order of the antagonisms of Ca2+, Se4+ and Zn2+ against Cd2+ toxicity was Ca2+>Se4+>Zn2+. The degree of antagonisms of Ca2+, Se4+ and Zn2+ against Cd2+ related to their concentration ratio.
Zhang
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Y
Department of Life Science, Shanxi University, Taiyuan 030006, China.
Xiao
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H
D002104:Cadmium / Q000037:antagonists & inhibitors / Q000633:toxicity*; D002118:Calcium / Q000494:pharmacology*; D002869:Chromosome Aberrations / Q000235:genetics*; D004396:Coloring Agents / Q000737:chemistry; D001467:Hordeum / Q000187:drug effects / Q000235:genetics* / Q000528:radiation effects; D048629:Micronuclei, Chromosome-Defective / Q000187:drug effects / Q000528:radiation effects*; D008940:Mitotic Index; D018517:Plant Roots / Q000166:cytology / Q000187:drug effects / Q000528:radiation effects; D012394:Rosaniline Dyes / Q000737:chemistry; D012643:Selenium / Q000494:pharmacology*; D015032:Zinc / Q000494:pharmacology*
D004396:Coloring Agents; D012394:Rosaniline Dyes; D002104:Cadmium; C006898:carbol-fuchsin solution; D012643:Selenium; D015032:Zinc; D002118:Calcium