title: [Nasal scleroma (rhinoscleroma): pathological and clinical results].
abstract: Histologic, immunohistochemical and ultrastructural results of a rhinoscleroma diagnosed bioptically on a 38 aged man are demonstrated. The characteristic light microscopic sign is a plasmocytic inflammatory infiltrate with dense packed foamy transformed macrophages (Mikulicz cells) ultrastructurally containing diplobacilli (Klebsiella rhinoscleromatis, gram negative agent of the lesion). The lesion has to be differentiated as of other inflammatory diseases as of plasmocytoma. A local application of acriflavin solution 2% was of therapeutical benefit.
authors.affiliation: Institut für Pathologie, Westfälischen Wilhelms-Universität Münster.
authors.forename: C
authors.initials: C
authors.lastname: August
authors.forename: B
authors.initials: B
authors.lastname: Hustert
mesh_terms: D000167:Acriflavine / Q000627:therapeutic use; D000328:Adult; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D009669:Nose Neoplasms / Q000175:diagnosis / Q000473:pathology; D010954:Plasmacytoma / Q000175:diagnosis / Q000473:pathology; D012226:Rhinoscleroma / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology*
chemical_list: D000167:Acriflavine
vernacular_title: Die nasale Skleromkrankheit (Rhinosklerom). Pathologie und Klinik.