Optic neuritis following albendazole therapy for orbital cysticercosis.
OBJECTIVE
To report the occurrence of optic neuritis following oral albendazole therapy for orbital cysticercosis.


METHODS
Two patients having definitively diagnosed orbital cysticercosis at the orbital apex developed an acute visual loss 1 week after initiation of oral albendazole. Ultrasonography and magnetic resonance imaging determined that the cause was optic neuritis due to disorganization of the cyst with inflammation of the adjacent optic nerve.


RESULTS
Oral corticosteroids (prednisolone 1 mg/kg per day) given for a period of 4 weeks led to resolution of the optic neuritis, with full visual recovery.


CONCLUSIONS
Corticosteroids should be given in addition to albendazole in the treatment of orbital cysticercosis when cysts are in close proximity to the optic nerve.
Tandon
R
R
Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi. radhika@medinst.ernet.in
Sihota
R
R
Dada
T
T
Verma
L
L
D000284:Administration, Oral; D000328:Adult; D015766:Albendazole / Q000008:administration & dosage / Q000009:adverse effects*; D000818:Animals; D000909:Antibodies, Helminth / Q000032:analysis; D000923:Anticestodal Agents / Q000008:administration & dosage / Q000009:adverse effects*; D003551:Cysticercosis / Q000175:diagnosis / Q000188:drug therapy* / Q000469:parasitology; D003552:Cysticercus / Q000276:immunology; D015822:Eye Infections, Parasitic / Q000175:diagnosis / Q000188:drug therapy* / Q000469:parasitology; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009902:Optic Neuritis / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy; D009916:Orbital Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000469:parasitology; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D014792:Visual Acuity
D000909:Antibodies, Helminth; D000923:Anticestodal Agents; D005938:Glucocorticoids; D011239:Prednisolone; D015766:Albendazole