Models for the in-host dynamics of malaria revisited: errors in some basic models lead to large over-estimates of growth rates.
The mathematical model of the in-host dynamics for malaria parasites of Anderson, R. M., May, R. M. & Gupta, S. (1989), Parasitology 99 (Suppl.) S59-S79, and subsequently used by other authors, contains an error. This leads to very substantial over-estimates in parasite growth rates. A corrected form of the model is presented in this paper.
Saul
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Queensland Institute of Medical Research, Royal Brisbane Hospital, Australia. allanS@qimr.edu.au
D000818:Animals; D004912:Erythrocytes / Q000469:parasitology*; D006790:Host-Parasite Interactions / Q000502:physiology; D016778:Malaria, Falciparum / Q000469:parasitology*; D008962:Models, Theoretical; D010963:Plasmodium falciparum / Q000254:growth & development* / Q000502:physiology