title: A surprising function for the PTEN tumor suppressor.
authors.forename: K
authors.initials: K
authors.lastname: Hopkin
mesh_terms: D000818:Animals; D017209:Apoptosis; D002455:Cell Division; D016147:Genes, Tumor Suppressor; D006801:Humans; D051379:Mice; D009154:Mutation; D009369:Neoplasms / Q000378:metabolism / Q000473:pathology*; D051059:PTEN Phosphohydrolase; D018129:Phosphatidylinositol Phosphates / Q000378:metabolism*; D010744:Phosphoric Monoester Hydrolases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D010766:Phosphorylation; D017346:Protein Serine-Threonine Kinases; D011518:Proto-Oncogene Proteins / Q000378:metabolism; D051057:Proto-Oncogene Proteins c-akt; D015398:Signal Transduction; D014407:Tumor Cells, Cultured; D025521:Tumor Suppressor Proteins
chemical_list: D018129:Phosphatidylinositol Phosphates; D011518:Proto-Oncogene Proteins; D025521:Tumor Suppressor Proteins; C060974:phosphatidylinositol 3,4,5-triphosphate; D017346:Protein Serine-Threonine Kinases; D051057:Proto-Oncogene Proteins c-akt; D010744:Phosphoric Monoester Hydrolases; D051059:PTEN Phosphohydrolase; C494929:PTEN protein, human