title: Three dimensional electron spin resonance (ESR) imaging of internal organs in living mice.
abstract: In vivo electron spin resonance imaging (ESR imaging) was applied to living mice after peroral administration of a nitroxide radical spin probe. A 3D ESR imaging procedure was applied in vivo in order to obtain the exact distribution of the spin probe in a living animal. The imaging pictures demonstrated that the administered spin probe was firstly located in the stomach, then delivered to the liver, kidney and heart of the animal.
authors.affiliation: ESR Application Laboratory, Application & Research Center, Analytical Instruments Division, JEOL LTD., Tokyo, Japan.
authors.forename: T
authors.initials: T
authors.lastname: Masumizu
authors.forename: K
authors.initials: K
authors.lastname: Fujii
authors.forename: M
authors.initials: M
authors.lastname: Kohno
authors.forename: S
authors.initials: S
authors.lastname: Nagai
authors.forename: Y
authors.initials: Y
authors.lastname: Odagaki
authors.forename: M
authors.initials: M
authors.lastname: Imanari
authors.forename: A
authors.initials: A
authors.lastname: Mori
authors.forename: L
authors.initials: L
authors.lastname: Packer
mesh_terms: D000818:Animals; D004578:Electron Spin Resonance Spectroscopy / Q000379:methods*; D005260:Female; D051379:Mice; D009589:Nitrogen Oxides / Q000493:pharmacokinetics; D013113:Spin Labels; D014018:Tissue Distribution
chemical_list: D009589:Nitrogen Oxides; D013113:Spin Labels; C039900:nitroxyl