title: [A sibling of delayed post-anoxic encephalopathy after strangulation].
abstract: A sibling of three year old girl and a year old boy, showed delayed post-anoxic encephlopathy after strangulation. After three days of the accident, the girl developed tetraplegia and choreo-athetosis. Her brother also developed choreo-athetosis two weeks after strangulation. T2 weighted MRI revealed a high signal intensity in the bilateral putamen and caudate nucleus. After hyperbaric oxygen therapy for two months, their symptoms diminished. We hypothesize that the functional damage of the neurons occurred in the bilateral basal ganglia as delayed neuronal death because of their vulnerability and peculiarity of the local circulation. Hyperbaric oxygen therapy may be effective in rescuing the neurons from hypoxia.
authors.affiliation: Department of Child Development, Kumamoto University Medical School.
authors.forename: M
authors.initials: M
authors.lastname: Matsui
authors.forename: K
authors.initials: K
authors.lastname: Kimoto
authors.forename: A
authors.initials: A
authors.lastname: Tomoda
authors.forename: M
authors.initials: M
authors.lastname: Matsukura
authors.forename: Y
authors.initials: Y
authors.lastname: Ohtani
authors.forename: T
authors.initials: T
authors.lastname: Miike
mesh_terms: D001237:Asphyxia / Q000150:complications*; D001264:Athetosis / Q000209:etiology; D002675:Child, Preschool; D002819:Chorea / Q000209:etiology; D005260:Female; D006801:Humans; D002534:Hypoxia, Brain / Q000209:etiology* / Q000473:pathology; D007223:Infant; D008297:Male; D013406:Suicide, Attempted; D013997:Time Factors; D016896:Treatment Outcome