title: [Prevalence of uro-nephrologic complications of urinary bilharziasis in hyperendemic focus in Madagascar].
abstract: This prospective study was designed to look for and describe urologic and nephrologic consequences of urinary bilharziosis due to schistosoma haematobium in a hyperendemic hotbed in the middle west of Madagascar. Methodology included clinical examination, kidney and bladder ultrasonography, urine dipsticks and creatininemia. Amongst a population of 574 persons aged 5 years ore more, 436 (76%) had bilharziosis ova in the urine (filtration method). From the clinical point of view, 257 patients (58.9%) had microscopic hematuria, 178 (40.8%) had presently an hematuria; 111 patients (25.5%) suffered from dysuria; 18 patients (4.1%) had limb oedema when 3 patients had present oedema (0.7%). Among 436 checked people, 267 (61.2%) had an ultrasonography abnormality. In 252, it was bladder wall abnormalities (57.8%). They were wall irregularities in 182 cases (41.7%); vesico-ureteral reflux in 22 cases (5.3%); ureteral dilatations in 22 cases (5.3%) and pyelocalyceal dilatations in 61 cases (13.9%). Prevalence of proteinuria 75.2% (316 amongst 420 checked people) of whom 5.7% (24 cases) had 5 g/l or more. Hematuria was found in 352 patients (83.8%) of whom 238 (56.7%) had more than 250 erythrocytes per microliter. Prevalence of leucocyturia was 56.7% (238 cases). Creatininemia was measured in 140 people with positive filtration; it was normal in all except two patients. This study highlights the parallel evolution between parasitic infection and uronephrological manifestations of the disease.
authors.affiliation: Service de médecine interne, Centre hospitalier universitaire Befelatanana, Antananarivo.
authors.forename: M H
authors.initials: MH
authors.lastname: Rasendramino
authors.forename: H R
authors.initials: HR
authors.lastname: Rajaona
authors.forename: C E
authors.initials: CE
authors.lastname: Ramarokoto
authors.forename: V E
authors.initials: VE
authors.lastname: Ravaoalimalala
authors.forename: P
authors.initials: P
authors.lastname: Leutscher
authors.forename: D
authors.initials: D
authors.lastname: Cordonnier
authors.forename: P
authors.initials: P
authors.lastname: Esterre
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D002648:Child; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000453:epidemiology / Q000209:etiology*; D008270:Madagascar / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D012553:Schistosomiasis haematobia / Q000150:complications* / Q000453:epidemiology; D001745:Urinary Bladder Diseases / Q000453:epidemiology / Q000209:etiology*
vernacular_title: Prévalence des retentissements uro-néphrologiques de la bilharziose urinaire dans un foyer hyperendémique de Madagascar.