Oscillations of the human sensorimotor system as revealed by magnetoencephalography.
Neurons in the human brain, especially in thalamic nuclei and the cerebral cortex, exhibit intrinsic membrane oscillations, which may be synchronized into network oscillations and form the macroscopic rhythms detectable with electroencephalography (EEG) and magnetoencephalography (MEG). Recent data also suggest that certain neurologic disorders may be associated with the occurrence of pathologically synchronized oscillatory brain activity. Human tremors may be the behavioral correlate of such abnormal brain rhythms. This article summarizes the current literature about sensorimotor oscillatory activity in people recorded by MEG and discusses the possible functional significance of the findings for motor control in health and disease.
Volkmann
J
J
Department of Neurology, Heinrich-Heine-University, Dusseldorf, Germany.
D001683:Biological Clocks / Q000502:physiology*; D002540:Cerebral Cortex / Q000502:physiology*; D004569:Electroencephalography; D004576:Electromyography / Q000379:methods; D006801:Humans; D015225:Magnetoencephalography / Q000379:methods*; D014202:Tremor / Q000175:diagnosis*