title: Pneumoperitoneum for laparoscopic cholecystectomy is not associated with compromised splanchnic circulation.
abstract: OBJECTIVE
  To investigate the influence of increased intra-abdominal pressure during pneumoperitoneum on splanchnic circulation.
  
  
  METHODS
  Open study.
  
  
  METHODS
  University hospital, Sweden.
  
  
  METHODS
  Five otherwise healthy patients (mean age of 34 years), undergoing laparoscopic cholecystectomy.
  
  
  METHODS
  Arterial and hepatic vein catheterization and simultaneous arterial and hepatic vein blood gas sampling in the awake state, during anaesthesia, after the establishment of pneumoperitoneum (intra-abdominal pressure level 11-13 mmHg) and after 30 and 60 minutes of pneumoperitoneum.
  
  
  METHODS
  Hepatic blood flow was estimated by the continuous infusion method and used as a measure of splanchnic blood flow. Splanchnic oxygen consumption was calculated according to the Fick principle.
  
  
  CONCLUSIONS
  Splanchnic blood flow and splanchnic oxygen consumption were not affected by pneumoperitoneum at this level of intra-abdominal pressure.
authors.affiliation: Department of Anaesthesiology and Intensive Care, Huddinge Hospital, Sweden.
authors.forename: S
authors.initials: S
authors.lastname: Odeberg
authors.forename: O
authors.initials: O
authors.lastname: Ljungqvist
authors.forename: A
authors.initials: A
authors.lastname: Sollevi
mesh_terms: D000005:Abdomen; D000328:Adult; D017081:Cholecystectomy, Laparoscopic; D002769:Cholelithiasis / Q000601:surgery*; D005260:Female; D006801:Humans; D010101:Oxygen Consumption; D011028:Pneumoperitoneum, Artificial; D011312:Pressure; D013152:Splanchnic Circulation