Chromatin remodeling and transcription.
The chromatin structure is essential not only for the compact packaging of the eukaryotic genome but also for regulation of transcription. This article provides an overview of chromatin modification upon transcriptional activation or repression, and chromatin remodeling. Interestingly, recent data demonstrate that chromatin remodeling in the promoter region is necessary for transcription.
Hirose
S
S
Department of Developmental Genetics, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka, 411-8540, Japan. shirose@lab.nig.ac.jp
D000107:Acetylation; D000818:Animals; D002843:Chromatin / Q000737:chemistry* / Q000235:genetics* / Q000648:ultrastructure; D006801:Humans; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism; D014158:Transcription, Genetic; D015533:Transcriptional Activation; D015003:Yeasts / Q000235:genetics
D002843:Chromatin; D009687:Nuclear Proteins; D014157:Transcription Factors