title: Absorbed dose determination at short distance from 60Co and 192Ir brachytherapy sources.
abstract: This paper presents two methods for absorbed dose determination with ionization chambers at short distance from 60Co and 192Ir brachytherapy sources. The methods are modifications of the Bragg-Gray and large cavity principles given in the IAEA code of practice for high- and medium-energy photon beams. A non-uniformity correction factor to account for the non-uniform electron fluence in the air cavity is introduced into the methods. The absorbed dose rates were determined from ionization chamber measurements at distances between 1.5 and 5.0 cm from the brachytherapy sources. The agreement between the two methods is excellent in 60Co brachytherapy dosimetry. For 192Ir dosimetry, the difference is less than 2.5% at all distances. In absorbed dose rate calculations with the 60Co brachytherapy source, the ratios between calculated and experimentally determined absorbed dose rates are 0.987 and 0.994 depending on the method used for absorption and scatter correction. In 192Ir dosimetry, the large cavity principle gives almost identical values to those which can be obtained with the AAPM recommendations. Using the chambers according to the Bragg-Gray principle in 192Ir dosimetry, the agreement with AAPM calculated absorbed dose rates is within 2.5% at all distances. The uncertainty, expressed as one standard deviation, in the experimentally determined absorbed dose is estimated to be between 3 and 4%.
authors.affiliation: Department of Radiation Physics, University of Göteborg, Sahlgrenska University Hospital, Sweden.
authors.forename: H
authors.initials: H
authors.lastname: Tölli
authors.forename: K A
authors.initials: KA
authors.lastname: Johansson
mesh_terms: D000465:Algorithms; D055592:Biophysical Phenomena; D001703:Biophysics; D001918:Brachytherapy / Q000706:statistics & numerical data; D003037:Cobalt Radioisotopes / Q000627:therapeutic use*; D005069:Evaluation Studies as Topic; D006801:Humans; D007496:Iridium Radioisotopes / Q000627:therapeutic use*; D011874:Radiometry / Q000295:instrumentation / Q000706:statistics & numerical data; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000706:statistics & numerical data
chemical_list: D003037:Cobalt Radioisotopes; D007496:Iridium Radioisotopes