title: [Dose and contrast medium reduction in intravenous digital subtraction angiography by bolus sequence].
abstract: OBJECTIVE
  This study evaluates the dose area product, the amount of contrast media and the examination quality of the bolus chasing technique compared to the single-step technique in intravenous digital subtraction angiography.
  
  
  METHODS
  15 examinations each with bolus chasing and single-step technique were compared. The dose area product and the volume of contrast media were recorded. The examination quality was scored by two examiners.
  
  
  RESULTS
  With bolus chasing the volume of the administered contrast media could be decreased on average by 114 ml (43%). The difference between the dose area product of bolus chasing (722 dGy/cm2) and single-step technique (1910 dGy/cm2) was significant. No significant difference in examination quality was found.
  
  
  CONCLUSIONS
  The intravenous bolus chasing technique is a practicable method. Compared to the single-step technique it allows a remarkable dose reduction and a low consumption of contrast media without restriction of examination quality.
authors.affiliation: Klinik für Radiologische Diagnostik, RWTH Aachen.
authors.forename: J
authors.initials: J
authors.lastname: Rückforth
authors.forename: K
authors.initials: K
authors.lastname: Schürmann
authors.forename: D
authors.initials: D
authors.lastname: Vorwerk
authors.forename: R W
authors.initials: RW
authors.lastname: Günther
mesh_terms: D015901:Angiography, Digital Subtraction / Q000379:methods*; D001157:Arterial Occlusive Diseases / Q000000981:diagnostic imaging*; D001783:Blood Flow Velocity / Q000502:physiology; D003287:Contrast Media / Q000008:administration & dosage*; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D006801:Humans; D007262:Infusions, Intravenous; D007866:Leg / Q000098:blood supply*; D011829:Radiation Dosage; D012680:Sensitivity and Specificity
chemical_list: D003287:Contrast Media
vernacular_title: Dosis- und Kontrastmitteleinsparung bei der intravenösen digitalen Subtraktionsangiographie durch Bolusverfolgung.