title: Validation of protein models derived from experiment.
abstract: The growing number of protein structures solved at atomic resolution holds the promise of further improvements in geometry-based validation parameters. Additionally, the estimated standard uncertainties of the atomic coordinates have been computed for a number of X-ray structures, providing a measure of the coordinate precision. In NMR spectroscopy, a measure analogous to the crystallographic R-factor has been developed.
authors.affiliation: Department of Crystallography, Birkbeck College, University of London, UK. roman@biochem.ucl.ac.uk
authors.forename: R A
authors.initials: RA
authors.lastname: Laskowski
authors.forename: M W
authors.initials: MW
authors.lastname: MacArthur
authors.forename: J M
authors.initials: JM
authors.lastname: Thornton
mesh_terms: D018360:Crystallography, X-Ray; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular; D011487:Protein Conformation; D011506:Proteins / Q000737:chemistry*; D015203:Reproducibility of Results
chemical_list: D011506:Proteins