[Biochemical criteria for assessing the severity of the status of wounded patients with gunshot damages to the chest and abdomen].
The biochemical assessment of severity was made in 34 patients with thoracic and abdominal gunshot wounds (12 uncomplicated; 11 with purulent, and 11 non-purulent complications). The levels of hormones, biogenic amines, lipid peroxidation (LP) indices, and antioxidant system (AOS) in serum were studied in 1, 3, 7, 14 days after admission. It was documented that the integral indices: cortisol/insulin and LP/AOS ratios were the most informative biochemical criteria for the assessment of severity of the injured patients. A high informative significance of these indices in the assessment of severity of homeostatic disturbances is pathogenetically substantiated due to stress-realizing (cortisol and free-radical LP components) and stress-limiting (insulin and AOS components) factors.
Abakumov
M M
MM
Pogodina
A N
AN
Golikov
P P
PP
Davydov
B V
BV
Fedorova
N V
NV
Nikolaeva
N Iu
NIu
Marchenko
V V
VV
D000007:Abdominal Injuries / Q000097:blood / Q000175:diagnosis*; D000293:Adolescent; D000328:Adult; D000975:Antioxidants / Q000378:metabolism; D001679:Biogenic Amines / Q000097:blood; D015415:Biomarkers / Q000097:blood; D005260:Female; D006728:Hormones / Q000097:blood; D006801:Humans; D015227:Lipid Peroxidation; D008297:Male; D008875:Middle Aged; D009104:Multiple Trauma / Q000097:blood / Q000175:diagnosis*; D013898:Thoracic Injuries / Q000097:blood / Q000175:diagnosis*; D013997:Time Factors; D015599:Trauma Severity Indices; D014948:Wounds, Gunshot / Q000097:blood / Q000175:diagnosis*
D000975:Antioxidants; D001679:Biogenic Amines; D015415:Biomarkers; D006728:Hormones
Biokhimicheskie kriterii otsenki tiazhesti sostoianiia ranenykh s ognestrel'nymi povrezhdeniiami grudi i zhivota.