title: [The incidence of bilateral multiple primary breast cancer among the female inhabitants of Crimea].
abstract: A method is proposed for calculation of PMSO frequency depending on succession of origination of polyneoplasias. The incidence rate of synchronous bilateral breast cancer (BC) was calculated in reference to all primary BC patients and came to 0.75%. The incidence rate of metachronous bilateral BC was calculated depending on the number of those BC patients having been registered every year of observation and it was found to be 5.4%. The total frequency of bilateral BC in a 20-year follow-up in the Crimean region appeared to be 6.15%. The incidence of metachronous bilateral BC was noted to be dependent on the length of follow-up: 1.27 percent and 4.14 percent in the 3- to 10- and 11- to 20-year periods respectively. The risk for the development of bilateral BC is conditioned by the time having elapsed since detection of the first tumor and increases after 10 and 18 years.
authors.forename: G N
authors.initials: GN
authors.lastname: Tel'kina
authors.forename: V M
authors.initials: VM
authors.lastname: Sorkin
mesh_terms: D001943:Breast Neoplasms / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D009367:Neoplasm Staging; D009378:Neoplasms, Multiple Primary / Q000453:epidemiology* / Q000473:pathology; D016609:Neoplasms, Second Primary / Q000453:epidemiology / Q000473:pathology; D013997:Time Factors; D014455:Ukraine / Q000453:epidemiology
vernacular_title: Chastota bilateral'nogo pervichno-mnozhestvennogo raka molochnoĭ zhelezy sredi zhitel'nits Kryma.