title: Mesial temporal lobe measurements on magnetic resonance imaging scans.
abstract: Changes in the mesial temporal lobe, particularly in the hippocampus, amygdala, and entorhinal cortex, are reported to occur in several neuropsychiatric conditions. Neuroimaging provides a non-invasive means of studying these changes. We present a method for reliably measuring the hippocampus, amygdala, and entorhinal cortex on MRI. The advantages of our method include high reliability, the use of orthogonal views in delineating boundaries and circumscription of measurement such that no tissue of any one anatomic structure is included in the measurement of another structure.
authors.affiliation: Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD 21287-7362, USA. honey@welchlink.welch.jhu.edu
authors.forename: N A
authors.initials: NA
authors.lastname: Honeycutt
authors.forename: P D
authors.initials: PD
authors.lastname: Smith
authors.forename: E
authors.initials: E
authors.lastname: Aylward
authors.forename: Q
authors.initials: Q
authors.lastname: Li
authors.forename: M
authors.initials: M
authors.lastname: Chan
authors.forename: P E
authors.initials: PE
authors.lastname: Barta
authors.forename: G D
authors.initials: GD
authors.lastname: Pearlson
mesh_terms: D000679:Amygdala / Q000033:anatomy & histology; D019412:Anatomy, Cross-Sectional / Q000379:methods; D001699:Biometry / Q000379:methods*; D018728:Entorhinal Cortex / Q000033:anatomy & histology; D006624:Hippocampus / Q000033:anatomy & histology; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008032:Limbic System / Q000033:anatomy & histology*; D008279:Magnetic Resonance Imaging; D015588:Observer Variation; D013702:Temporal Lobe / Q000033:anatomy & histology*