title: Light microscopy of uveoscleral drainage routes after gelatine injections into the suprachoroidal space.
abstract: OBJECTIVE
  To visualize the suprachoroidal space and to study the morphology of possible uveoscleral drainage routes in the human eye.
  
  
  METHODS
  Indian ink stained gelatine was injected directly into the suprachoroidal space of 7 human donor eyes. Those quadrants where gelatine appeared in the episcleral venous network were cut in their entirety in consecutive sections and examined by light microscopy.
  
  
  RESULTS
  Gelatine was observed in the connective tissue surrounding scleral vessels and nerves. Gelatine was also traceable in fine, endothelium-lined channels at the inner aspect of the anterior sclera. These channels seemed to originate at the inner surface of the sclera, close behind the scleral spur, and communicate with the intrascleral venous plexus.
  
  
  CONCLUSIONS
  Fluid is drained from the suprachoroidal space through the perivascular and perineural spaces of scleral blood vessels and nerves. In addition, this study indicates that there are preformed channels at the inner aspect of the anterior sclera, capable of draining fluid directly into scleral veins.
authors.affiliation: Department of Ophthalmology, University of Bergen, Norway.
authors.forename: J
authors.initials: J
authors.lastname: Krohn
authors.forename: T
authors.initials: T
authors.lastname: Bertelsen
mesh_terms: D000368:Aged; D001082:Aqueous Humor / Q000502:physiology; D002102:Cadaver; D002244:Carbon; D002829:Choroid / Q000098:blood supply* / Q000166:cytology; D004396:Coloring Agents; D003238:Connective Tissue / Q000033:anatomy & histology; D005780:Gelatin / Q000008:administration & dosage; D006801:Humans; D007267:Injections; D008833:Microcirculation; D008875:Middle Aged; D012039:Regional Blood Flow / Q000502:physiology; D012590:Sclera / Q000098:blood supply* / Q000166:cytology / Q000294:innervation; D014602:Uvea / Q000098:blood supply* / Q000166:cytology / Q000294:innervation; D014680:Veins / Q000502:physiology
chemical_list: D004396:Coloring Agents; C028433:chinese ink; D002244:Carbon; D005780:Gelatin