Human somatostatin receptor mediated antiproliferative action evokes subtype selective cytotoxic and cytostatic signaling.
Srikant
C B
CB
Fraser Laboratories, Royal Victoria Hospital, Montreal, Quebec, Canada. mdcs@musica.mcgill.ca
D000818:Animals; D017209:Apoptosis / Q000187:drug effects / Q000235:genetics; D016466:CHO Cells / Q000187:drug effects / Q000378:metabolism; D002453:Cell Cycle / Q000187:drug effects / Q000235:genetics; D002455:Cell Division / Q000187:drug effects / Q000502:physiology*; D006224:Cricetinae; D004720:Endonucleases / Q000378:metabolism; D016193:G1 Phase / Q000187:drug effects / Q000235:genetics; D006801:Humans; D015282:Octreotide; D011518:Proto-Oncogene Proteins / Q000187:drug effects / Q000378:metabolism; D019253:Proto-Oncogene Proteins c-bcl-2; D017481:Receptors, Somatostatin / Q000187:drug effects / Q000502:physiology*; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction; D016159:Tumor Suppressor Protein p53 / Q000187:drug effects / Q000235:genetics / Q000378:metabolism; D051028:bcl-2-Associated X Protein
D011518:Proto-Oncogene Proteins; D019253:Proto-Oncogene Proteins c-bcl-2; D017481:Receptors, Somatostatin; D011994:Recombinant Proteins; D016159:Tumor Suppressor Protein p53; D051028:bcl-2-Associated X Protein; D004720:Endonucleases; D015282:Octreotide