title: Effectiveness of resins in neutralizing antibiotic activities in bactec plus Aerobic/F culture medium.
abstract: Incorporating resins in blood culture media can effectively reduce the activities of several antibiotics. It was shown that the activities of some generally used antibiotics decreased by 80 to 90% within 2 h in Bactec Plus Aerobic/F resin-containing culture medium. Bactec vials containing resins were still found to be positive for bacteria when antibiotics were present. The addition of beta-lactamase shortened the detection time irrespective of the presence of resins.
authors.affiliation: Department of Medical Microbiology, Leiden University Medical Centre, 2300 RC, Leiden, The Netherlands.
authors.forename: J
authors.initials: J
authors.lastname: Spaargaren
authors.forename: C P
authors.initials: CP
authors.lastname: van Boven
authors.forename: G P
authors.initials: GP
authors.lastname: Voorn
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification*; D016470:Bacteremia / Q000382:microbiology*; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification*; D003470:Culture Media; D006801:Humans; D012116:Resins, Plant / Q000494:pharmacology*
chemical_list: D000900:Anti-Bacterial Agents; D003470:Culture Media; D012116:Resins, Plant