title: Native valve staphylococcal endocarditis: etiology, risk factors and outcome in 53 cases.
abstract: Fifty-three cases of staphylococcal endocarditis from a national endocarditis survey were analyzed for risk factors and outcome. Thirty of 53 patients had predisposing heart disease (39.6% rheumatic fever) but only 3 were on dialysis, only 2 had central venous catheter, only 2 intravenous drug abuse but 7 had prior cardiosurgery. Mortality was 39.6%. In analyzing risk factors for death, attributable mortality was significantly associated with skin infections (P < 0.05), embolization (P < 0.02), inappropriate therapy (P < 0.005) either because of too short therapy (P < 0.003) or wrong antibiotic combination (P < 0.01). Surgical therapy was associated with better outcome (4.8% deaths vs. 31.2% survivors, P < 0.04).
authors.affiliation: National Institute of Cardiovascular Disease, Bratislava, Slovakia.
authors.forename: V
authors.initials: V
authors.lastname: Hricak
authors.forename: F
authors.initials: F
authors.lastname: Matejicka
authors.forename: T
authors.initials: T
authors.lastname: Sedlák
authors.forename: I
authors.initials: I
authors.lastname: Duris
authors.forename: V
authors.initials: V
authors.lastname: Milovský
authors.forename: J
authors.initials: J
authors.lastname: Kovacik
authors.forename: P
authors.initials: P
authors.lastname: Marks
authors.forename: D
authors.initials: D
authors.lastname: West
authors.forename: V
authors.initials: V
authors.lastname: Krcméry
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents; D004359:Drug Therapy, Combination / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000188:drug therapy / Q000209:etiology*; D005260:Female; D006349:Heart Valve Diseases / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011446:Prospective Studies; D012307:Risk Factors; D013203:Staphylococcal Infections / Q000188:drug therapy / Q000209:etiology*
chemical_list: D000900:Anti-Bacterial Agents