[Pleural malignant mesothelioma with osseous cartilaginous and rhabdomyogenic differentiation].
A 63-year-old man, who was formerly an asbestos factory worker who had been followed due to asbestosis, and was admitted to our hospital with left chest pain and dyspnea on exertion. A chest X-ray and chest computed tomogram (CT) on admission revealed a large tumor in the left lung field. Percutaneous needle biopsy determined that the tumor was a sarcoma. No clinical response was obtained by systemic chemotherapy. The autopsy revealed diffuse malignant mesothelioma of sarcomatous type with osseous, cartilaginous and rhabdomyogenic differentiation. Osseous and cartilaginous differentiation in a malignant mesothelioma is rare, and the presence of a malignant rhabdomyogenic component is the first to be described in the Japanese literature.
Okamoto
T
T
Department of Respiratory Disease, National Toneyama Hospital.
Yokota
S
S
Shinkawa
K
K
Kimura
H
H
Nishino
K
K
Ito
M
M
Ogura
T
T
Hanada
M
M
D001195:Asbestosis / Q000150:complications; D001842:Bone and Bones / Q000473:pathology*; D002356:Cartilage / Q000473:pathology*; D002454:Cell Differentiation; D006801:Humans; D008297:Male; D008654:Mesothelioma / Q000473:pathology*; D008875:Middle Aged; D009132:Muscles / Q000473:pathology*; D010997:Pleural Neoplasms / Q000473:pathology*