title: Kinematic analysis of the reach to grasp movement in Parkinson's and Huntington's disease subjects.
abstract: This experiment investigates the kinematic characteristics of the reach to grasp movement of Parkinson's and Huntington's disease subjects under two different experimental conditions. In the first condition subjects were required to perform the movement at a normal speed, while in the second condition they were required to perform the movement as fast as possible. Results showed that the kinematic parameterization of movement in Parkinson's disease subjects did not differ from that of age-matched control subjects for both the normal and the fast condition. However, the performances of Huntington's disease subjects appeared to be different when compared to the other two groups. Differences were mainly related to Huntington's disease patients' inability to properly define the temporal features of the movements.
authors.affiliation: Dipartimento di Psicologia, Universita' di Bologna, European Medical Center, Italy. pan3720@iperbole.bologna.it
authors.forename: C
authors.initials: C
authors.lastname: Bonfiglioli
authors.forename: G
authors.initials: G
authors.lastname: De Berti
authors.forename: P
authors.initials: P
authors.lastname: Nichelli
authors.forename: R
authors.initials: R
authors.lastname: Nicoletti
authors.forename: U
authors.initials: U
authors.lastname: Castiello
mesh_terms: D000328:Adult; D017668:Age of Onset; D000368:Aged; D000704:Analysis of Variance; D000978:Antiparkinson Agents / Q000627:therapeutic use; D001479:Basal Ganglia / Q000503:physiopathology*; D002746:Chlorpromazine / Q000627:therapeutic use; D005260:Female; D006220:Haloperidol / Q000627:therapeutic use; D018737:Hand Strength / Q000502:physiology*; D006801:Humans; D006816:Huntington Disease / Q000235:genetics / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009068:Movement / Q000502:physiology*; D009460:Neurologic Examination; D010300:Parkinson Disease / Q000503:physiopathology*
chemical_list: D000978:Antiparkinson Agents; D006220:Haloperidol; D002746:Chlorpromazine