Multiple coronary artery graft occlusion in a fatal case of heparin-induced thrombocytopenia.
Heparin-induced thrombocytopenia (HIT) is a potentially life-threatening condition when immune-mediated platelet aggregation results in thromboembolic complications. A case is detailed of multiple saphenous vein graft thromboses and cardiac mural thrombi in a patient who died from complications of HIT.
Burke
A P
AP
Department of Cardiovascular Pathology, Armed Forces Institute of Pathology, Washington, DC 20306-6000, USA. burke@email.afip.osd.mll
Mezzetti
T
T
Farb
A
A
Zech
E R
ER
Virmani
R
R
D001026:Coronary Artery Bypass; D017809:Fatal Outcome; D005260:Female; D005343:Fibrinolytic Agents / Q000009:adverse effects*; D006083:Graft Occlusion, Vascular / Q000139:chemically induced*; D006331:Heart Diseases / Q000139:chemically induced; D006493:Heparin / Q000009:adverse effects*; D006801:Humans; D008875:Middle Aged; D013921:Thrombocytopenia / Q000139:chemically induced*; D013927:Thrombosis / Q000139:chemically induced*
D005343:Fibrinolytic Agents; D006493:Heparin