Very high cytochrome P4501A2 activity and nonresponse to clozapine.
Bender
S
S
Eap
C B
CB
D000328:Adult; D014150:Antipsychotic Agents / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D003024:Clozapine / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D019388:Cytochrome P-450 CYP1A2 / Q000187:drug effects / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D011569:Psychiatric Status Rating Scales; D012559:Schizophrenia / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy*; D012907:Smoking / Q000378:metabolism; D016896:Treatment Outcome
D014150:Antipsychotic Agents; D019388:Cytochrome P-450 CYP1A2; D003024:Clozapine