The physiologic response of domestic animals to ionizing radiation: a review.
With respect to clinical signs of the radiation syndromes, some remarkable species variations exist. For example the marked delayed reaction of the acute hematologic response in cows. An unusually high sensitivity of the central nervous system is found in burros, which is probably caused by acute vascular and/or metabolic changes in the brain. The species-specific number of intestinal crypt and hemopoietic stem cells may explain the early survival differences among species after high doses of irradiation. Mortality due to acute radiation syndromes is lowest in chickens. Regarding late effects, various neoplasms are typical in dogs, and cattle more commonly develop cataracts.
von Zallinger
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C
Institut für Pharmakologie, Toxikologie und Pharmazie der Tierärztlichen Fakultät der Universität München, Germany.
Tempel
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K
D000208:Acute Disease; D000818:Animals; D000829:Animals, Domestic / Q000293:injuries; D001921:Brain / Q000098:blood supply / Q000378:metabolism / Q000528:radiation effects; D002386:Cataract / Q000662:veterinary; D002417:Cattle; D002645:Chickens; D004285:Dogs; D018397:Equidae; D006402:Hematologic Diseases / Q000662:veterinary; D006412:Hematopoietic Stem Cells / Q000528:radiation effects; D007413:Intestinal Mucosa / Q000528:radiation effects; D009381:Neoplasms, Radiation-Induced / Q000662:veterinary; D011829:Radiation Dosage; D011830:Radiation Effects; D011832:Radiation Injuries / Q000662:veterinary*; D011836:Radiation Tolerance; D011839:Radiation, Ionizing; D013045:Species Specificity; D015996:Survival Rate