Usefulness of pindolol in neurocardiogenic syncope.
We prospectively studied the efficacy of pindolol, a beta-adrenergic blocker with intrinsic sympathomimetic activity (ISA), for the prevention of syncope recurrences in 31 patients with recurrent neurocardiogenic syncope. Pindolol proved to be an effective treatment, even in patients who had previously failed treatment with conventional beta blockers, suggesting a clinical benefit from addition of ISA to beta blockade in this setting.
Iskos
D
D
Cardiac Arrhythmia Center, Department of Medicine, University of Minnesota School of Medicine, Minneapolis 55455, USA.
Dutton
J
J
Scheinman
M M
MM
Lurie
K G
KG
D000293:Adolescent; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010869:Pindolol / Q000627:therapeutic use*; D011446:Prospective Studies; D019462:Syncope, Vasovagal / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control; D018667:Tilt-Table Test; D016896:Treatment Outcome
D000319:Adrenergic beta-Antagonists; D010869:Pindolol