title: Case-control study on risk factors for testicular cancer.
abstract: Occupational exposures were assessed in a case-control study on testicular cancer using self administered questionnaires. Answers were obtained for 148 (91%) cases and 314 (87%) controls. Of the cases 101 had seminoma and 47 had embryonal testicular cancer. Occupational plastics work yielded odds ratio (OR) 2.9 with 95% confidence interval (CI) 1.3-6.5. Increased risk was found for embryonal cancer regarding farming (OR 3.1; CI 1.03-9.1) and contact with farm animals (OR 3.3; CI 1.00-10.9), but not for seminoma. For all testicular cancer exposure to insects repellents, mostly containing N,N-diethyl-m-toluamide (DEET) gave OR 1.7; CI 1.03-2.8, with a dose-response effect. Somewhat increased risks were found for amateur radio operators (OR 2.2; CI 0.7-6.6), work with radar equipment (OR 2.0; CI 0.3-14.2) and engineers in electronics and telecommunication industry (OR 2.3; CI 0.8-6.7) based on few exposed subjects, however. Video display unit work gave OR 1.5; CI 0.98-2.3 and for exposure 480 working days (median number) the risk increased further to OR 1.8; CI 1.1-3.2. Because of low numbers of exposed subjects in some calculations some of these results might be spurious and need to be further studied.
authors.affiliation: Department of Oncology, Orebro Medical Center, S-701 85 Orebro, Sweden.
authors.forename: L
authors.initials: L
authors.lastname: Hardell
authors.forename: A
authors.initials: A
authors.lastname: Näsman
authors.forename: C G
authors.initials: CG
authors.lastname: Ohlson
authors.forename: M
authors.initials: M
authors.lastname: Fredrikson
mesh_terms: D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016273:Occupational Exposure; D016017:Odds Ratio; D011143:Polyvinyl Chloride / Q000009:adverse effects; D012307:Risk Factors; D011795:Surveys and Questionnaires; D013736:Testicular Neoplasms / Q000453:epidemiology / Q000209:etiology*
chemical_list: D011143:Polyvinyl Chloride