title: The association between selected metabolic parameters and left abomasal displacement in dairy cows.
abstract: The objective of this study was to examine the association between selected metabolic parameters and subsequent left displaced abomasum (LDA) diagnosis in dairy cows. Forty-four LDA cows sampled in the third week ante partum (a.p.) which was at a median of 34 days prior to LDA diagnosis, 36 LDA cows sampled in the first week post partum (p.p.) which was at a median of 14 days prior and 28 LDA cows sampled in the second week p.p., which was at a median of 9 days prior to LDA diagnosis were used. Each case was matched to 3 controls by herd and calving date. Data were available from a large field study. Aspartate-aminotransferase (AST) activity, the concentrations of beta-hydroxybutyrate (BHB), glucose, calcium and urea in blood, and the body condition score (BCS) were studied. Logistic regression was used to analyse the association between these parameters and subsequent LDA, adjusting for the effects of parity and pretreatment. A separate model was used for each sampling week and each parameter. In the third week a.p. none of the parameters were significantly associated with LDA. AST and BHB sampled in the first week p.p. and in the second week p.p. were significantly associated with LDA diagnosis. The higher the AST and BHB, the higher the odds of being diagnosed subsequently with LDA. The lower glucose and Ca in the second week p.p. the higher the odds of subsequent LDA diagnosis. Urea and BCS were not significantly associated with LDA in any of the weeks examined. We conclude that AST and BHB in the first and second week p.p. might be used as tests for subsequent LDA. Glucose, calcium, urea and body condition were either not significantly associated with LDA or significantly associated only in the second week p.p.; this may limit their use as tests for LDA.
authors.affiliation: Department of Population Medicine, Ontario Veterinary College, University of Guelph, Canada.
authors.forename: T
authors.initials: T
authors.lastname: Geishauser
authors.forename: K
authors.initials: K
authors.lastname: Leslie
authors.forename: T
authors.initials: T
authors.lastname: Duffield
authors.forename: D
authors.initials: D
authors.lastname: Sandals
authors.forename: V
authors.initials: V
authors.lastname: Edge
mesh_terms: D020155:3-Hydroxybutyric Acid / Q000097:blood; D000018:Abomasum / Q000002:abnormalities*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood; D001786:Blood Glucose / Q000378:metabolism; D002118:Calcium / Q000097:blood; D002417:Cattle / Q000002:abnormalities*; D002418:Cattle Diseases / Q000517:prevention & control; D003692:Delayed-Action Preparations; D005260:Female; D007662:Ketosis / Q000517:prevention & control / Q000662:veterinary; D008985:Monensin / Q000008:administration & dosage / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000517:prevention & control / Q000662:veterinary*; D014508:Urea / Q000097:blood
chemical_list: D001786:Blood Glucose; D003692:Delayed-Action Preparations; D014508:Urea; D008985:Monensin; D001219:Aspartate Aminotransferases; D002118:Calcium; D020155:3-Hydroxybutyric Acid