title: Chemical basis for alkali cation selectivity in potassium-channel proteins.
abstract: The determination of the crystal structure of a K+-selective channel protein from Streptomyces lividans reveals how the rapid movement of K+ across membranes is catalyzed by a large family of pore-forming proteins. Many features of the structure mirror hypotheses, predictions and models of K+ channels developed over the past four decades of functional analysis.
authors.affiliation: Department of Pharmacology Department of Cellular and Molecular Physiology Yale University School of Medicine New Haven Connecticut 06520-8066 USA. edward.moczydlowski@yale.edu.
authors.forename: E
authors.initials: E
authors.lastname: Moczydlowski
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D002412:Cations; D006801:Humans; D008969:Molecular Sequence Data; D015221:Potassium Channels / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry
chemical_list: D002412:Cations; D015221:Potassium Channels; D011506:Proteins