title: Chlamydia trachomatis IncA is localized to the inclusion membrane and is recognized by antisera from infected humans and primates.
abstract: Chlamydia psittaci produces a collection of proteins, termed IncA, IncB, and IncC, that are localized to the chlamydial inclusion membrane. In this report we demonstrate that IncA is also produced by Chlamydia trachomatis. C. trachomatis IncA is structurally similar to C. psittaci IncA and is also localized to the inclusion membrane. Immunoblot analysis demonstrated that sera from C. trachomatis-infected patients and from experimentally infected monkeys both recognized C. trachomatis IncA.
authors.affiliation: Department of Microbiology, Oregon State University, Corvallis, Oregon 97331-3804, USA.
authors.forename: J P
authors.initials: JP
authors.lastname: Bannantine
authors.forename: W E
authors.initials: WE
authors.lastname: Stamm
authors.forename: R J
authors.initials: RJ
authors.lastname: Suchland
authors.forename: D D
authors.initials: DD
authors.lastname: Rockey
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000097:blood*; D001426:Bacterial Proteins; D002451:Cell Compartmentation; D002690:Chlamydia Infections / Q000097:blood; D002692:Chlamydia trachomatis / Q000276:immunology*; D002691:Chlamydophila psittaci; D006801:Humans; D008252:Macaca fascicularis; D008565:Membrane Proteins / Q000276:immunology* / Q000302:isolation & purification; D010750:Phosphoproteins / Q000276:immunology* / Q000302:isolation & purification; D017386:Sequence Homology, Amino Acid; D013045:Species Specificity
chemical_list: D000907:Antibodies, Bacterial; D001426:Bacterial Proteins; C094163:IncA protein, bacteria; D008565:Membrane Proteins; D010750:Phosphoproteins