title: Comparative investigations of algorithms for the detection of breaths in newborns with disturbed respiratory signals.
abstract: The correct detection of the beginning of inspiration and expiration in the respiratory signals is an essential prerequisite for accurate lung function testing in newborns. Five algorithms for breath detection using pneumotachographically measured flow and volume signals were investigated with regard to the error rate. To compare and to evaluate the reliability of these algorithms 12 minimally and 12 severely disturbed flow and volume signals from spontaneously breathing newborns were used. With the exception of an algorithm based on Walsh-transformed signals, all algorithms work reliably (error rate <1.1%) if disturbances are minimal. In severely disturbed signals there is a great difference between the algorithms. The most robust algorithm tested (trigger of the flow signal with an additional plausibility check of the recognized breath) resulted in an error rate of <3.4%. Not all algorithms tested are suitable for real-time applications because they differ considerably in delay time for breath detection.
authors.affiliation: Department of Pediatrics (Charité), Humboldt University, Berlin, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Schmidt
authors.forename: B
authors.initials: B
authors.lastname: Foitzik
authors.forename: R R
authors.initials: RR
authors.lastname: Wauer
authors.forename: F
authors.initials: F
authors.lastname: Winkler
authors.forename: G
authors.initials: G
authors.lastname: Schmalisch
mesh_terms: D000465:Algorithms; D016477:Artifacts; D005069:Evaluation Studies as Topic; D006801:Humans; D007231:Infant, Newborn / Q000502:physiology*; D007234:Infant, Premature; D001239:Inhalation / Q000502:physiology; D012123:Pulmonary Ventilation / Q000502:physiology; D015203:Reproducibility of Results; D012129:Respiratory Function Tests; D012143:Respiratory Physiological Phenomena; D012140:Respiratory Tract Diseases / Q000175:diagnosis; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted; D013990:Tidal Volume / Q000502:physiology; D013997:Time Factors; D014160:Transducers, Pressure