title: Mammographic appearance of recurrent breast carcinoma in six patients with TRAM flap breast reconstructions.
abstract: OBJECTIVE
  To determine the mammographic appearance of locally recurrent cancer in patients with breast reconstructions with transverse rectus abdominis musculocutaneous (TRAM) flaps after mastectomy for primary breast cancer.
  
  
  METHODS
  The mammograms and records of women treated for breast cancer with mastectomy and TRAM flap reconstruction who developed local recurrences from 1995 to 1997 were reviewed retrospectively. Eight cancers were identified in six women. Five women had palpable abnormalities, and the sixth had cancer detected at screening mammography at another institution. Mean age at recurrence was 48 years.
  
  
  RESULTS
  All eight cancers were visible on mammograms: four masses, two pleomorphic microcalcifications, and two masses with calcifications. Four of the eight were in the upper central portion of the breast. Before reconstruction, the original histologic diagnosis for all cases had been multifocal ductal carcinoma in situ. All recurrences were invasive cancer. Median time from the original diagnosis of breast cancer to diagnosis of recurrence was 42 months. Two of four patients who subsequently underwent axillary node dissection had metastatic disease in the lymph nodes. The single patient who underwent mammographic screening (elsewhere) had negative axillary lymph nodes.
  
  
  CONCLUSIONS
  The mammographic appearance of recurrent carcinoma in TRAM flap reconstructions is similar to that of primary breast cancer.
authors.affiliation: Department of Radiology, University of Michigan Hospitals, Taubman Center, Ann Arbor 48109-0326, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Helvie
authors.forename: T E
authors.initials: TE
authors.lastname: Wilson
authors.forename: M A
authors.initials: MA
authors.lastname: Roubidoux
authors.forename: E G
authors.initials: EG
authors.lastname: Wilkins
authors.forename: A E
authors.initials: AE
authors.lastname: Chang
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D005260:Female; D006801:Humans; D016462:Mammaplasty / Q000379:methods*; D008327:Mammography; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging*; D012189:Retrospective Studies; D013524:Surgical Flaps