title: Diclofenac analgesia following cleft palate surgery.
abstract: OBJECTIVE
  This prospective study looked at the postoperative hemorrhage risk associated with the use of diclofenac following cleft palate repair.
  
  
  METHODS
  Twenty consecutive children (6 months to 9 years of age) requiring repair of the hard or soft palate were included.
  
  
  METHODS
  Single per rectum doses of diclofenac were given at 1 mg/kg following cleft palate repair, with additional doses every 12 hours.
  
  
  CONCLUSIONS
  The use of the nonsteroidal anti-inflammatory drug, diclofenac, for postoperative analgesia is well established for many types of surgery. The authors find that twice daily diclofenac rectal suppositories provide very good analgesia postcleft palate repair. This, combined with supplemental oral paracetamol, obviates the need for opiates, resulting in alert infants who feed well and are suitable for early discharge.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Norfolk and Norwich Hospital, United Kingdom.
authors.forename: P
authors.initials: P
authors.lastname: Sylaidis
authors.forename: T J
authors.initials: TJ
authors.lastname: O'Neill
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage; D000285:Administration, Rectal; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects; D002648:Child; D002675:Child, Preschool; D002972:Cleft Palate / Q000150:complications / Q000601:surgery*; D004008:Diclofenac / Q000008:administration & dosage / Q000009:adverse effects; D004359:Drug Therapy, Combination; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011182:Postoperative Care / Q000009:adverse effects; D019106:Postoperative Hemorrhage / Q000139:chemically induced; D013488:Suppositories
chemical_list: D018712:Analgesics, Non-Narcotic; D000894:Anti-Inflammatory Agents, Non-Steroidal; D013488:Suppositories; D004008:Diclofenac; D000082:Acetaminophen