Postradiation morphea.
We describe a 54-year-old woman who developed right breast morphea after radiotherapy following a lumpectomy for infiltrating lobular carcinoma. Skin biopsy confirmed the histological features of morphea. Treatment was initiated with both topical and intralesional steroid, resulting in marked improvement. Morphea following radiotherapy is an infrequently recognized phenomenon. However, when diagnosed early it may be effectively managed with local steroid treatment.
Gollob
M H
MH
Department of Medicine, Sunnybrook Health Science Centre, Toronto, Ontario, Canada.
Dekoven
J G
JG
Bell
M J
MJ
Assaad
D
D
Rao
J
J
D000287:Administration, Topical; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D018275:Carcinoma, Lobular / Q000188:drug therapy / Q000532:radiotherapy / Q000601:surgery; D002990:Clobetasol / Q000031:analogs & derivatives / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D005938:Glucocorticoids; D006801:Humans; D008875:Middle Aged; D011832:Radiation Injuries; D012594:Scleroderma, Localized / Q000209:etiology* / Q000473:pathology
D000893:Anti-Inflammatory Agents; D005938:Glucocorticoids; D002990:Clobetasol