Philadelphia positive acute lymphoblastic leukemia 16 years after the apparent cure of acute lymphoblastic leukemia. New leukemia or late relapse?
A Philadelphia-positive ALL in an adult occurring 21 years after the initial diagnosis is reported here. This case raises the question as to whether or not this event is a relapse or a new leukemia. A possible role of interferon-alpha previously administered to the patient for a chronic viral hepatitis is discussed too.
Navarro
J L
JL
de Blas Orlando
J
J
Ríos Herranz
E
E
González Campos
J
J
Parody
R
R
Rodríguez Fernández
J M
JM
D000328:Adult; D000998:Antiviral Agents / Q000009:adverse effects; D002051:Burkitt Lymphoma / Q000175:diagnosis*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D006526:Hepatitis C / Q000188:drug therapy; D006521:Hepatitis, Chronic / Q000188:drug therapy; D006801:Humans; D016898:Interferon-alpha / Q000009:adverse effects / Q000627:therapeutic use; D008297:Male; D016609:Neoplasms, Second Primary / Q000175:diagnosis*; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis*; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology; D012008:Recurrence; D013997:Time Factors
D000998:Antiviral Agents; D016898:Interferon-alpha