[Ability of erythrocytes to deposit thyroid hormones: regulatory role of physico-chemical factors in vitro].
Data obtained suggest the existence of regulation mechanism controlling parameters of thyroid status, that does not require any modification of thyroid gland secretory function. The realisation of this mechanism can involve hormone-depositing function of blood erythrocytes, which is sensitive to a) change of regional or systemic pH and b) change of hematocrit. Results of the present study indicate that mammalian erythrocytes are able to bind considerable quantities of T3 and T4 and, T3 binding is preferable.
Dolomatov
S I
SI
Bucovina State Medical Academy, Chernovtsy, Ukraine.
Pishak
V P
VP
Slipeniuk
T S
TS
Meshchishen
I F
IF
Okopnaia
T V
TV
D000818:Animals; D001665:Binding Sites; D002417:Cattle; D004912:Erythrocytes / Q000378:metabolism*; D006400:Hematocrit; D006863:Hydrogen-Ion Concentration; D013963:Thyroid Hormones / Q000378:metabolism*
D013963:Thyroid Hormones
Sposobnost' éritrotsitov deponirovat' tireoidnye gormony: reguliatornaia rol' fiziko-khimicheskikh faktorov in vitro.