[The reaction of the rat thymus to xenotransplantation and immunosuppression].
To the complex action of human embryonal neocortex transplanted into the eye anterior chamber and cyclosporin A injected daily to prevent graft rejection rat thymus reacts by accidental involution, layer inversion and vascular disturbances (without hematoma formation). After 3 wks reparative period sets in and by the end of 5th wk thymus approximates to the control in all parameters.
Puchkov
V F
VF
Department of Morphology, Russian Academy of Medical Sciences, St. Petersburg.
Smirnov
E B
EB
Otellin
V A
VA
D000818:Animals; D016380:Brain Tissue Transplantation / Q000473:pathology*; D016572:Cyclosporine / Q000627:therapeutic use; D006801:Humans; D007165:Immunosuppression Therapy; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D019579:Neocortex / Q000196:embryology / Q000637:transplantation*; D051381:Rats; D017208:Rats, Wistar; D013950:Thymus Gland / Q000187:drug effects / Q000473:pathology*; D013997:Time Factors; D014183:Transplantation, Heterologous
D007166:Immunosuppressive Agents; D016572:Cyclosporine
Reaktsiia timusa krysy na ksenotransplantatsiiu i immunosupressiiu.