[New allergens and pediatric allergology].
The first manifestation of allergies most often occurs in childhood. Prevention of atopic diseases is one of the very important tasks in pediatrics. Exact knowledge of allergens and the role of adjuvant factors in allergic sensitisation is necessary to define measures for allergy prevention aiming at a reduction of the worldwide increasing prevalence of atopic diseases. Indoor allergens and tobacco smoke exposure are risk factors for early sensitisation and asthma. In addition to house dust mites there are other indoor allergens like moulds, pet allergens, cockroaches and many more. Exact diagnosis and identification of the causative allergen allows therapy directing towards allergen avoidance and relieving symptoms without need of any additional pharmaceutical treatment. This cost-saving strategy helps to prevent disease-related long absences from school and work. Exact knowledge of the structure and biology of the etiologic allergens is a prerequisite for this treatment strategy. We review the great contribution of the Allergy Unit in Zurich to the identification and characterisation of environmental allergens.
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Kinderklinik Aarau und Ostschweizer Kinderspital St. Gallen.
D000328:Adult; D000485:Allergens / Q000009:adverse effects*; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000175:diagnosis / Q000209:etiology* / Q000534:rehabilitation; D008297:Male; D008875:Middle Aged
D000485:Allergens
Neue Allergene und pädiatrische Allergologie.