title: Changing HIV infection rates and risk in an African-American community cohort.
abstract: This longitudinal study of a homogeneously urban African-American community cohort drawn from the metropolitan New York area (USA) analyzed three-year change in HIV-1 antibody prevalence and self-reported risk practices separately for men and women. Specifically, risk practices reported on personal interviews and results from blood sero-assay in 1989-1990 were compared to similar interview reports of risk practices and HIV assay from saliva samples in 1993. Results showed: (1) women's infection rates increased more than men's, resulting in a male to female infection ratio of 1.5:1; (2) heterosexual transmission accounted for most of women's new infection; (3) in multivariate analysis, multiple partners was a significant heterosexual risk indicator for both men and women, increasing infection odds five-fold; and (4) buying sex also increased heterosexual men's infection odds approximately five-fold. Results document increasing rates of African-American HIV infection linked largely to heterosexual exposure risk, that the African-American male-female infection ratio resembles the global rather than North American one, and also the utility of an expanded classification of heterosexual exposure risk.
authors.affiliation: Columbia University, New York, NY 10032, USA.
authors.forename: A F
authors.initials: AF
authors.lastname: Brunswick
authors.forename: M J
authors.initials: MJ
authors.lastname: Flory
mesh_terms: D000328:Adult; D001741:Black or African American / Q000706:statistics & numerical data*; D003625:Data Collection / Q000592:standards; D005260:Female; D015483:HIV Antibodies / Q000032:analysis; D015658:HIV Infections / Q000453:epidemiology / Q000208:ethnology* / Q000276:immunology; D015528:HIV Seroprevalence; D020010:Heterosexuality; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009518:New York / Q000453:epidemiology; D015995:Prevalence; D018570:Risk Assessment; D012309:Risk-Taking; D012747:Sexual Partners; D015819:Substance Abuse, Intravenous / Q000208:ethnology
chemical_list: D015483:HIV Antibodies