title: MRI of focal cortical dysplasia.
abstract: We studied nine cases of focal cortical dysplasia (FCD) by MRI, with surface-rendered 3D reconstructions. One case was also examined using single-voxel proton MR spectroscopy (MRS). The histological features were reviewed and correlated with the MRI findings. The gyri affected by FCD were enlarged and the signal of the cortex was slightly increased on T1-weighted images. The gray-white junction was indistinct. Signal from the subcortical white matter was decreased on T1- and increased on T2-weighted images in most cases. Contrast enhancement was seen in two cases. Proton MRS showed a spectrum identical to that of normal brain.
authors.affiliation: Department of Radiology, St. Louis Children's Hospital, MO 63110, USA. benlee@mirlink.wustl.edu
authors.forename: B C
authors.initials: BC
authors.lastname: Lee
authors.forename: R E
authors.initials: RE
authors.lastname: Schmidt
authors.forename: G A
authors.initials: GA
authors.lastname: Hatfield
authors.forename: B
authors.initials: B
authors.lastname: Bourgeois
authors.forename: T S
authors.initials: TS
authors.lastname: Park
mesh_terms: D002540:Cerebral Cortex / Q000737:chemistry / Q000473:pathology*; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007223:Infant; D008279:Magnetic Resonance Imaging; D009682:Magnetic Resonance Spectroscopy