The persistence of leptospiral agglutinins titers in human sera diagnosed by the microscopic agglutination test.
The persistence of agglutinins detected by MAT has created some problems to the interpretation of the results. The aim of this study was to examine the data of serology from 70 patients with serologically confirmed diagnosis of leptospirosis by during 3-13 months after being affected with leptospires in order to elucidate the interpretation of the persistence of agglutinins detected by MAT. Sixty-one patients sera (87.14%) had titers equal or greater than 800. Of these, two individuals maintained titers of 800 thirteen months after the onset. This study showed that only one sample of sera with high titers is not reliable to determine the time at which infection occurred.
Romero
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EC
Adolfo Lutz Institute, Department of Medical Biology, São Paulo, Brazil.
Caly
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CR
Yasuda
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PH
D000372:Agglutination Tests / Q000379:methods*; D000373:Agglutinins / Q000097:blood*; D000907:Antibodies, Bacterial / Q000097:blood*; D006801:Humans; D007919:Leptospira / Q000276:immunology*; D007922:Leptospirosis / Q000097:blood / Q000276:immunology* / Q000382:microbiology; D015203:Reproducibility of Results; D013997:Time Factors
D000373:Agglutinins; D000907:Antibodies, Bacterial