title: Pretreatment staging of endoscopically early gastric cancer with a 15 MHz ultrasound catheter probe.
abstract: BACKGROUND
  The usefulness of and problems associated with an ultrasound catheter probe in the pretreatment staging of endoscopically early gastric cancer remain unexplored.
  
  
  METHODS
  Endoscopic ultrasonography using a 15 MHz catheter probe of 2.6 mm diameter was performed in a prospective study to determine the pretherapy staging of endoscopically early gastric cancer in 78 patients. The results of the ultrasound images were compared with the histologic findings of the specimens obtained by endoscopic mucosal resection or surgical resection.
  
  
  RESULTS
  The accuracy of the catheter probe for depth of invasion of endoscopically early gastric cancers was 67% (52 of 78 patients). The accuracy in determining depth of invasion in relation to endoscopic type was significantly higher for the elevated type (91%) than for the depressed type of early cancer (56%) (p < 0.01). The staging accuracy classified by histologic type was significantly higher for differentiated (86%) than for undifferentiated (18%) cancer (p < 0.01). Staging accuracy decreased as tumor size increased. The accuracy, sensitivity, and specificity for nodal staging were 80%, 17%, and 90%, respectively.
  
  
  CONCLUSIONS
  A 15 MHz ultrasound catheter probe is most useful for determining depth of invasion when the tumor is histologically differentiated and endoscopically of the small elevated type early gastric cancer, but it is unreliable in the diagnosis of metastatic lymph nodes.
authors.affiliation: Third Department of Internal Medicine, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Akahoshi
authors.forename: Y
authors.initials: Y
authors.lastname: Chijiwa
authors.forename: S
authors.initials: S
authors.lastname: Hamada
authors.forename: I
authors.initials: I
authors.lastname: Sasaki
authors.forename: H
authors.initials: H
authors.lastname: Nawata
authors.forename: T
authors.initials: T
authors.lastname: Kabemura
authors.forename: D
authors.initials: D
authors.lastname: Yasuda
authors.forename: H
authors.initials: H
authors.lastname: Okabe
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019160:Endosonography / Q000295:instrumentation*; D005260:Female; D020699:Gastroscopes; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009367:Neoplasm Staging; D011446:Prospective Studies; D011846:Radio Waves; D012680:Sensitivity and Specificity; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*