Insulin gene transfer compensates pancreatic beta-cell function in diabetic rats.
Yamaguchi
M
M
Department of Surgery, Showa University Fujigaoka Hospital, Yokohama, Japan.
Kuzume
M
M
Matsumoto
T
T
Shimura
H
H
Nakano
H
H
Kumada
K
K
Takeda
M
M
D000256:Adenoviridae; D000818:Animals; D001786:Blood Glucose / Q000378:metabolism; D002460:Cell Line; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D018014:Gene Transfer Techniques; D005822:Genetic Vectors; D006801:Humans; D007328:Insulin / Q000096:biosynthesis* / Q000097:blood / Q000235:genetics; D007515:Islets of Langerhans / Q000378:metabolism*; D007668:Kidney; D011384:Proinsulin / Q000235:genetics*; D011498:Protein Precursors / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics; D051381:Rats; D017207:Rats, Sprague-Dawley; D014162:Transfection / Q000379:methods
D001786:Blood Glucose; D007328:Insulin; D011498:Protein Precursors; D012333:RNA, Messenger; C013737:preproinsulin; D011384:Proinsulin