title: Acute airway obstruction in a child with acute lymphoblastic leukaemia during central venous catheterization.
abstract: We report the case of a seven-year-old girl with recently diagnosed acute lymphoblastic leukaemia (ALL) who suffered acute airway obstruction during insertion of a central venous catheter under general anaesthesia. The central airway obstruction was due to a mixture of leukaemic cells, blood clot and fibrin. There is discussion about airway obstruction both as a complication of central line insertion and secondary to ALL. The pulmonary complications of ALL, with particular reference to pulmonary haemorrhage, are detailed. The management of blood clot obstructing the central airway is discussed.
authors.affiliation: Department of Anaesthesia, British Columbia's Children's Hospital, Vancouver, Canada.
authors.forename: P M
authors.initials: PM
authors.lastname: Sanderson
authors.forename: E
authors.initials: E
authors.lastname: Hartsilver
mesh_terms: D000402:Airway Obstruction / Q000209:etiology*; D000768:Anesthesia, General; D001980:Bronchi / Q000473:pathology; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D002648:Child; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal; D017254:Leukemic Infiltration / Q000150:complications; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications*; D013350:Subclavian Vein; D013927:Thrombosis / Q000150:complications; D014132:Trachea / Q000473:pathology