[Adalat effects on clinical course of coronary heart disease, peripheral circulation and myocardial perfusion in patients with stenosing coronary atherosclerosis].
OBJECTIVE
To study adalate effects on the clinical picture, systemic microcirculation and myocardial blood flow in postmyocardial infarction patients.


METHODS
Adalate was given for two weeks in a daily dose 30 mg to 17 patients with angina of effort who had survived macrofocal myocardial infarction. The examination was made with tetrapolar chest rheography, polarography, biomicroscopy, computed tomography.


RESULTS
Positive clinical changes were seen in 92% of the treated patients: the need in nitroglycerine reduced 1.8 times, muscular performance rose by 24%, skin O2 tension increased by 37.5%, central hemodynamics, microcirculation and myocardial blood flow improved noticeably.


CONCLUSIONS
Adalate has a good antianginal and antiischemic action due to positive hemodynamic effects.
Garganeeva
A A
AA
Tepliakov
A T
AT
Chernov
V I
VI
Braslavskaia
T G
TG
D000328:Adult; D001783:Blood Flow Velocity / Q000187:drug effects; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D003326:Coronary Circulation / Q000187:drug effects; D005500:Follow-Up Studies; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D008875:Middle Aged; D017202:Myocardial Ischemia / Q000175:diagnosis / Q000188:drug therapy* / Q000503:physiopathology; D009543:Nifedipine / Q000627:therapeutic use*; D010992:Plethysmography, Impedance; D011048:Polarography; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
D002121:Calcium Channel Blockers; D009543:Nifedipine
Vliianie adalata na klinicheskoe techenie ishemicheskoĭ bolezni serdtsa, perifericheskoe krovoobrashchenie i perfuziiu miokarda u bol'nykh stenoziruiushchim koronarnym aterosklerozom.