title: Novel therapeutic strategies for colorectal cancer.
abstract: Advanced colorectal cancer is a significant cause of cancer mortality in industrialized countries. 5-fluorouracil has remained the principal drug used in treating this disease, and although it has tangibly improved patient outcome, further gains can potentially be made. This review focuses on the current development of novel therapeutic agents which have potential in the treatment of colorectal cancer.
authors.affiliation: CRC Institute for Cancer Studies, University of Birmingham.
authors.forename: D J
authors.initials: DJ
authors.lastname: Kerr
authors.forename: D R
authors.initials: DR
authors.lastname: Ferry
mesh_terms: D015179:Colorectal Neoplasms / Q000188:drug therapy* / Q000628:therapy; D004791:Enzyme Inhibitors / Q000627:therapeutic use*; D015316:Genetic Therapy; D006801:Humans; D007167:Immunotherapy; D013940:Thymidylate Synthase / Q000037:antagonists & inhibitors*; D059004:Topoisomerase I Inhibitors
chemical_list: D004791:Enzyme Inhibitors; D059004:Topoisomerase I Inhibitors; D013940:Thymidylate Synthase