title: [Prognostic factors in colorectal adenocarcinoma].
abstract: Aim of this study was to analyse prognostic factors of improved survival after resection of colorectal cancer. We studied 715 patients by retrospective review operated for colorectal adenocarcinoma. Survival was analyzed by the Kaplan-Maier method. Comparisons were made by log rank analysis. The overall survival is 75% at 1 years, 41.0% at 5 years, 29.7% at 10 years. A significant difference was noted in the survival rate according to age of the patients (p < 0.01), preoperative serum level of carcinoembryonic antigen (CEA) (p < 0.05), the performance status (p < 0.05), intestinal obstruction (p < 0.01), clinicopathological stage of the tumour (p < 0.05). Other factors including the sex, the clinical diagnosis of anaemia, the site of the tumour and histological grade had no apparent influence on survival. To define high-risk groups of recurrence is important for adjuvant therapy and follow-up study.
authors.affiliation: Istituto di Chirurgia Generale e Toracica, Ospedale Universitario di Nizza.
authors.forename: F
authors.initials: F
authors.lastname: Lagautrière
authors.forename: L
authors.initials: L
authors.lastname: Valvano
authors.forename: M
authors.initials: M
authors.lastname: Chaazl
authors.forename: D
authors.initials: D
authors.lastname: Benchimol
authors.forename: J L
authors.initials: JL
authors.lastname: Bernard
authors.forename: A
authors.initials: A
authors.lastname: Bourgeon
authors.forename: H
authors.initials: H
authors.lastname: Richelme
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012307:Risk Factors; D017678:Sex Distribution; D016019:Survival Analysis
vernacular_title: Fattori prognostici dell'adenocarcinoma colorettale.