title: Gender and survival after AIDS in Rio de Janeiro, Brazil.
abstract: The relation between gender and survival after a diagnosis of AIDS was studied in a cohort of patients with HIV infection in Rio de Janeiro, Brazil. During the study period, 124 of 617 patients (20%) developed AIDS. Of this group, 91 patients were men and 33 were women. There were no gender related differences regarding the access to antiretroviral therapy or to prophylaxis for Pneumocystis carinii pneumonia. Survival was shorter among women (hazard ratio [HR] = 4.43; p < .001) after adjustment for age and AIDS-defining condition. Adjusting for CD4+ and CD8+ counts reduced the difference between genders (HR = 3.33; p = .017). These results suggest that survival after an AIDS diagnosis may be shorter among women than men in Brazil. Further studies are needed to determine the factors that may be negatively influencing the prognosis of women with AIDS in Brazil.
authors.affiliation: Department of Preventive Medicine, Hospital Universitário Clementino Fraga Filho, Federal University of Rio de Janeiro, Brazil.
authors.forename: G
authors.initials: G
authors.lastname: Santoro-Lopes
authors.forename: L H
authors.initials: LH
authors.lastname: Harrison
authors.forename: L H
authors.initials: LH
authors.lastname: Moulton
authors.forename: L A
authors.initials: LA
authors.lastname: Lima
authors.forename: A M
authors.initials: AM
authors.lastname: de Pinho
authors.forename: C
authors.initials: C
authors.lastname: Hofer
authors.forename: M
authors.initials: M
authors.lastname: Schechter
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology; D000163:Acquired Immunodeficiency Syndrome / Q000188:drug therapy / Q000401:mortality*; D000328:Adult; D019380:Anti-HIV Agents / Q000627:therapeutic use; D001938:Brazil / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000401:mortality*; D006801:Humans; D008297:Male; D011020:Pneumonia, Pneumocystis / Q000453:epidemiology; D011379:Prognosis; D016016:Proportional Hazards Models; D017678:Sex Distribution; D015996:Survival Rate; D014505:Urban Population / Q000706:statistics & numerical data*
chemical_list: D019380:Anti-HIV Agents