Microsatellites in the HLA region: 1998 update.
In order to update the review published in Tissue Antigens in 1997, we present here a new overview on microsatellites in the HLA region, including additional information, with focus on the following points: * Description of 103 microsatellite characteristics in the HLA region, 50 markers having been newly described since 1996. * An integrated map of the HLA region, including microsatellites and some HLA genes, revealing an important microsatellite density in the MHC (Class I, Class II and Class III regions). * A synthesis of microsatellite analysis in disease studies, summarizing results of microsatellite approaches in 24 pathologies, including autoimmune diseases, HLA-associated or HLA-linked diseases and cancers. * Other applications of HLA region microsatellites in population or transplantation studies.
Foissac
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Département d'Epidémiologie, Economie de la Santé et Santé Communitaire, Faculté de Médecine, Toulouse, France.
Cambon-Thomsen
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D002874:Chromosome Mapping; D016208:Databases, Factual; D005260:Female; D006680:HLA Antigens / Q000235:genetics*; D006801:Humans; D020407:Internet; D008297:Male; D018895:Microsatellite Repeats / Q000235:genetics*
D006680:HLA Antigens