title: Staphylococcal strains involved in bovine mastitis are inhibited by Staphylococcus aureus antimicrobial peptides.
abstract: The inhibitory activity of five bacteriocin (Bac)-producer strains of Staphylococcus aureus was tested against bacteria pathogenic for cattle. Sixty-five epidemiologically unrelated strains of Staph. aureus involved in bovine mastitis were used as indicators in an agar diffusion test. Bacteriocins produced by four strains could inhibit only a limited number of test organisms. However, all 65 indicator strains proved to be susceptible to the combined action of both bacteriocins encoded by pRJ9, a Bac plasmid found in strain A53. Therefore, the bacteriocins produced by this strain may represent new antimicrobial peptides with potential applications in the prevention and treatment of bovine mastitis.
authors.affiliation: Departamento de Microbiologia Geral, Universidade Federal do Rio de Janeiro, Brazil.
authors.forename: S S
authors.initials: SS
authors.lastname: de Oliveira
authors.forename: J
authors.initials: J
authors.lastname: Abrantes
authors.forename: M
authors.initials: M
authors.lastname: Cardoso
authors.forename: D
authors.initials: D
authors.lastname: Sordelli
authors.forename: M C
authors.initials: MC
authors.lastname: Bastos
mesh_terms: D000818:Animals; D000898:Antibiosis / Q000502:physiology*; D001430:Bacteriocins / Q000378:metabolism*; D002417:Cattle; D005260:Female; D008413:Mastitis / Q000382:microbiology*; D008892:Milk / Q000382:microbiology; D013211:Staphylococcus aureus / Q000378:metabolism / Q000502:physiology*
chemical_list: D001430:Bacteriocins