Blood pressure in children exposed prenatally to cocaine.
Prenatal exposure to cocaine may alter autonomic nervous system function resulting in hypertension. Blood pressure was measured oscillometrically in a convenience sample of cocaine-exposed (n = 32) and nonexposed (n = 23) children, aged 8 to 26 months, by examiners unaware of exposure status. The exposed and nonexposed groups did not differ in systolic pressure (mean +/- SD 102.3 +/- 9.9 mmHg vs 119.1 +/- 19.4). Prenatal exposure to cocaine does not appear to be associated with elevated blood pressure in young children.
Needlman
R
R
Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Frank
D A
DA
Cabral
H
H
Mirochnick
M
M
Kwon
C
C
Zuckerman
B
B
D001341:Autonomic Nervous System / Q000187:drug effects; D001794:Blood Pressure / Q000187:drug effects; D002675:Child, Preschool; D003042:Cocaine / Q000009:adverse effects*; D005260:Female; D005315:Fetal Diseases / Q000139:chemically induced; D005333:Fetus / Q000187:drug effects*; D006801:Humans; D006973:Hypertension / Q000139:chemically induced*; D007223:Infant; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced*; D011297:Prenatal Exposure Delayed Effects
D003042:Cocaine