title: [Late cellular potentials in patients after myocardial infarction--a result of left ventricular diastolic disfunction?].
abstract: The link between left ventricular dysfunction and arrhythmogenesis is commonly known. However, so far, only the systolic left ventricular dysfunction has been evaluated. Because of the controversial results of those studies, we decided to assess if is there a link between late potentials (LP) and left ventricular diastolic dysfunction. Our material consisted of 56 patients: 11 women and 45 men, mean age was 61.12 +/- 10.07 years. Signal averaged ECG and ECHO were performed in each patient, 2-3 months after myocardial infarction. For high pass filter of 40 Hz, LP were defined as 2 or 3 abnormal SAECG variables (the averaged QRS > 114 ms, the low amplitude signal duration LAS > 38 ms and root mean square voltage of the terminal 40 ms RMS40 < 20 microV). During ECHO study, we assessed E and A waves E/A ratio, left ventricular end-diastolic volume (LVEDV), ejection fraction (EF), acceleration (AT) and deceleration times (DT). The patients were divided into 2 groups: group I-30 patients LP positive and group II-26 patients LP negative. There were no significant differences between the groups in terms of age, EF, and heart rate. We presented significant differences between group I and II in terms of E wave velocity (0.75 +/- 0.19 vs 0.64 +/- 0.19 p < 0.03) E/A ratio (2.13 +/- 1.56 vs 1.0 +/- 0.5 p < 0.05) respectively. We did not confirm significant differences as regards A wave velocity, AT, isovolumetric time (IVRT) and LVEDV between both tested groups. In group I we revealed a significant correlation between E wave (r = 0.45), E/A ratio (r = 0.62), AT (r = -0.42) E/A ratio (r = 0.56), DT (r = 0.55) and QRS, as well as DT and LPD (r = 0.40) and between IVRT and RMS40 (r = -0.43). The results of our study suggest that in patients after myocardial infarction: 1/incidence of LP depends on the degree of left ventricular filling pattern like in impaired relaxion, quite well correlated with filtered QRS time 3/in LP positive patients there was predominance of restrictive left ventricular filling pattern, quite well correlation with RMS40 amplitude.
authors.affiliation: Klinika Chorób Wewnetrznych i Kardyiologii CSK WAM.
authors.forename: L
authors.initials: L
authors.lastname: Kubik
authors.forename: A
authors.initials: A
authors.lastname: Cwetsch
authors.forename: A
authors.initials: A
authors.lastname: Skrobowski
authors.forename: M
authors.initials: M
authors.lastname: Cholewa
authors.forename: G
authors.initials: G
authors.lastname: Kade
authors.forename: G
authors.initials: G
authors.lastname: Kamiński
mesh_terms: D000328:Adult; D000368:Aged; D003971:Diastole; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000209:etiology*; D015995:Prevalence; D018487:Ventricular Dysfunction, Left / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology
vernacular_title: Późne potencjały komorowe u chorych po zawale serca--wynik upośledzenia funkcji rozkurczowej lewej komory?