title: Failure of psyllium mucilloid to hasten evaluation of sand from the equine large intestine.
abstract: OBJECTIVE
  To examine the efficacy of psyllium mucilloid in evacuating sand from the equine large intestine.
  
  
  METHODS
  12 clinically healthy pony geldings.
  
  
  METHODS
  Twelve ponies were assigned to 2 groups of six each. One group was treated with psyllium and the second was a control group. All ponies had an exploratory celiotomy and 10 g/kg body weight of sand was placed into the cecum. Ponies were fed a grain mixture alone at 1 g/kg (controls), a grain mixture plus psyllium pellets, each at 1 g/kg body weight (3 ponies), or fed a grain mixture and given psyllium powder by nasogastric tube at 1 g/kg body weight divided into two daily doses in 3 L of water (3 ponies). Radiographs were taken on days 1 (3 per group), 5 (all ponies), and 11 (3 per group) to monitor sand transit through the large intestine. Ponies were euthanatized 11 days after surgery. Sand was collected from the contents of the cecum, ventral colon, dorsal colon, and small colon. Dry weight of the recovered sand was compared between the two treatment groups as a percentage of the dry weight of sand placed in the cecum.
  
  
  RESULTS
  No significant differences were detected in the mean percentage of sand recovered between the two treatment groups (P < .05), with 39.2% recovered in ponies treated with psyllium and 27.4% recovered in control ponies.
  
  
  CONCLUSIONS
  Psyllium mucilloid had no apparent effect on sand evacuation from the equine large intestine. When intake of sand is prevented, the equine large intestine can reduce and possibly eliminate its sand burden.
authors.affiliation: Department of Veterinary Clinical Medicine, University of Illinois, College of Veterinary Medicine, Urbana 61802, USA.
authors.forename: P D
authors.initials: PD
authors.lastname: Hammock
authors.forename: D E
authors.initials: DE
authors.lastname: Freeman
authors.forename: G J
authors.initials: GJ
authors.lastname: Baker
mesh_terms: D000284:Administration, Oral; D000818:Animals; D002400:Cathartics / Q000008:administration & dosage / Q000627:therapeutic use*; D006734:Horse Diseases / Q000517:prevention & control*; D006736:Horses; D007415:Intestinal Obstruction / Q000517:prevention & control / Q000662:veterinary*; D007420:Intestine, Large / Q000000981:diagnostic imaging; D008297:Male; D011620:Psyllium / Q000008:administration & dosage / Q000627:therapeutic use*; D011859:Radiography; D012822:Silicon Dioxide / Q000009:adverse effects
chemical_list: D002400:Cathartics; D012822:Silicon Dioxide; D011620:Psyllium