A structural tree for proteins containing S-like beta-sheets.
A structural tree for proteins and domains containing S-like beta-sheets has been constructed. An S-like beta-sheet is taken as a starting structure in modelling or as a root structure of the tree. Larger structures are obtained by a stepwise addition of beta-strands and/or alpha-helices to the root S-like beta-sheet in accordance with a restricted set of rules inferred from known principles of protein structure. Applications of the structural tree to structure comparison, protein classification and protein folding are described.
Efimov
A V
AV
Institute of Protein Research, Russian Academy of Sciences, Pushchino, Moscow Region. efimov@protres.ru
D000465:Algorithms; D000818:Animals; D006801:Humans; D008954:Models, Biological; D008958:Models, Molecular; D017510:Protein Folding; D017433:Protein Structure, Secondary; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry*
D011506:Proteins